Query Results 

------------------------------------TAEERQNLYTFRDYVTKILDP---
---TYILS-------YMAPWFKEDEVQYIQAEKNNKGTVEAASLFLRFLLELQEEGWFRG
FMDALNHAGYSGLYEAIENWDFQKIEKLEEYRLLLRRLQPEFKTRIIPNDILPDISECLL
DQECEEIIQIC---SNKGPMAGAEKMVECLLRSDKENWPKSLKLALEKEES-KFSELWII
EKGAKDVALQDLE---DEEMKTSEVQIFYKEEPECQ-NLSENSCPPSEVSH-----THSP
MKP

PF00270 // ENSGT00510000046789_1_Domain_3 (304, 488)

RGYQLELALPAKNGKNTIICAPT-GCGKTFVSLLICEHHLQ-KFPQGQKGKVVFFAV
QIPVYEQQKSVF------SKYFERRGYKVSGISGATAENVSVEQIIEDNDIIILTPQILV
NSLKSGTVPSLSVFTLMIFDECHNTSKHHPYNMIMFNYLDQKLGGSSDSLPQVVGLTASV
GVGDAKS

ENSGT00510000046789_1_Linker_3_4 (488, 755)

TGEALEYICKLCASLDISVVATVKDNLEELEEVVYKPQKFFRKVESRTTDRFK
CIISQLMKETESLAKSIFDKLGTITLGNFSQIQNRNFGTQKYEQWIVAVQKKCMVLKMPD
KDEESRICKALFLYTSHLRKFNDALIISEHARMKDALDYLKD-FFRNV------------
-----------RTAGFDETEQD--LTRRFEEKLQELE-SISMDPSNENPKLKD---LCFV
LQEEYHLNPETRTILFVKTRALVDALKKWIEENP

PF00271 // ENSGT00510000046789_1_Domain_4 (755, 837)

KLSFLKPGILTGRGRTKQNIGMTLPA
QKDVLHTFKTSGDNKILIATSVADEGIDIAQCNLVILYEYVGNVIKMIQTRGRGRARGSK
CFLLTSNSDVIEKEKINIYKEKMMNDSILRLQTWDEAVFKEKVRQ---IQIHEKFIRDSQ
SK-VKPILDKENKKLLCRKCKTFACYTADIRVVEECHYTVVGDAFKKCFVSKLHPKPKNV
GSFEKKAKIFCARQDCCHDWGIHVKYKTFE-IPFIKIESFVVEDIATGVQTLYAKWRDFH
FEKLPFDAAEMPK--------------

-----------------------------------

PF16739 // ENSGT00510000046789_1_Domain_0 (36, 140)

MTAEQRRNLWAFHDYVRKTLDP---
---TYILA-------YMAPWLGEDQMQYIQAQKDSKGPMEAASLFLEFLLNLKEEGWFRG
FLDALFQAGYSGLYEAIET

ENSGT00510000046789_1_Linker_0_2 (140, 148)

WDFQKIEK

PF16739 // ENSGT00510000046789_1_Domain_2 (148, 233)

LEEHRSLLRRLQPEFKDRIIPTDILSDMSECLI
SQECEEIKQIC---SNKGMMAGAEKMVECLIRSDKENWPKILKLALEKEEN-

ENSGT00510000046789_1_Linker_2_3 (233, 313)

TFSQLWCV
GEGLIKVRD---V--EDDRIEASSIQIFFREDPDCL-NLSQNSCPPSDMTH---TNLNSP
LKPRNYQLELAL

PF04851 // ENSGT00510000046789_1_Domain_3 (313, 478)

PAKKGKNTIICAPT-GCGKTFVSLLICEHHLK-QFPEGQKGKVAFFAN
QVPVYLQQKSVF------SMYFERLGYKVAGISGATAESVPVQQTIENNDIIILTPQILV
NSLKQGSILSVSVFTLMIFDECHNTSKHHPYNMIMFSYLDQKLGGPSDPLPQVVGLT

ENSGT00510000046789_1_Linker_3_4 (478, 719)

ASV
GVGDATTVEEAMLYICRLCAALDASVIATVRENVEELEEVVYKPQKFFRKVESRTTDKFK
FIISQLIKETECLAKNVSEQL-----GHLFEIQNREIGTQKYEQWIVGVHKECMVFQMAD
KEEESRICKALFLYTSHLRRYNDALIISEHAQMKDALNYLKD-FFNNV------------
-----------RSAGFDEIEQD--LTRRFEEKVPELE-SISLDPSNENPKLKD---LY

PF00271 // ENSGT00510000046789_1_Domain_4 (719, 836)

LI
LQEEYHVNPETKTILFVKTRALVDALKNWIEENSALNFLKPGILTGRGRTGEVTGMTLPA
QKCVLDAFRANSNNNILIVTSVADEGIDIAQCNLIILYEYVGNVIKMIQTRGRGR

ENSGT00510000046789_1_Linker_4_5 (836, 914)

ARGSK
CFLLTSNADVIEKEQMNMYKEKMMNESISRLQAWDVAQFEKTVHR---IQIDEKFSRDSQ
QK-PKPAPVKENK

PF11648 // ENSGT00510000046789_1_Domain_5 (914, 1030)

KLLCGKCKGLACYTAEVRVIEDCHYTVVGNAFKERFVIKPHPKPKTY
GSFVKKAKIFCARPDCNHDWGIHVKYNAFE-IPVIKIQSFVVEDVATRAQTWFSRWKDFN
YEWTQFAPAEMSI--------------

-----------------------------------MTTEQRRSLLAFQDYIRKTLDP---
---TYILS-------YMAPWFREEEVQYIQAEKNNKGPMEAATLFLKFLLELQEEGWFRG
FLDALDHAGYSGLYEAIESWDFKKIEKLEEYRLLLKRLQPEFKTRIIPTDILSDLSECLI
NQECEEILQIC---STKGMMAGAEKLVECLLRSDKENWPKTLKLALERERN-KFSELWTV
EKGVKDVETEDLE---D-KMETSDIQIFYQEDPECQ-NLSENSCPPSEVSD---TNLYSP
FKPRNYQLELALPA

PF04851 // ENSGT00510000046789_1_Domain_3 (315, 456)

KKGKNTIICAPT-GCGKTLVSVLICEHHLK-KFPPGQKGKVVFFAN
QIPVYEQQESVF------SKYFERLGYRVTGISGATAENVPVEQIVENNDIIILTPQILV
NNLKKGTIPSLSVFTLMIFDECHNTSKQHPYNMIM

ENSGT00510000046789_1_Linker_3_4 (456, 775)

FNYLDQKLGGSSGPLPQVIGLTASV
GVGDAKDTDEALDYICKLCASLDASVIATVKDNLEELEQVVYKPQKFFRKVESRVSDKFK
CIIAQLMRDTESLAKRICKDL-----ESFSQIQNREFGTQKYEQWIVTVQKACMVFQMPD
KDEESRICKALFLYTSHLRKYNDALIISEHARMKDALDYLKD-FFSNV------------
-----------RAAGFDETEQD--LTQRFEEKLQELE-SVSRDPSNENPKLED---LCFI
LQEEYHLNPETITILFVKTRALVDALKNWIEGNPKLSFLKPGILTGRGKTNQNT

PF00271 // ENSGT00510000046789_1_Domain_4 (775, 836)

GMTLPA
QKCILDAFKVNGDHNILIATSVADEGIDIAQCNLVILYEYVGNVIKMIQTRGRGR

ENSGT00510000046789_1_Linker_4_5 (836, 911)

ARGSK
CFLLTSNAGVIEKEQINMYKEKMMNDSILRLQTWDEAVFREKILH---IQTHEKLIRDSQ
EK-PKPVPDK

PF11648 // ENSGT00510000046789_1_Domain_5 (911, 1032)

ENKKLLCGKCKALVCYTADIRVIEECHYTVLGDAFKECFVSRPHPKPKKF
SNFDKRGKIFCARQNCSHDWGIHVKYKIFE-IPVIKIESFVVEDIATGVQTLYSKWKDFH
FERIPFDPAEMAK--------------

-----------------------------------

PF16739 // ENSGT00510000046789_1_Domain_0 (36, 140)

MTAEQRRNLFAFENYIRKILDP---
---TYILS-------YMAPWLDDDKMQYIQAEKNNKGPMEAASLFLQFLLELQGTDWFRG
LLDALCHAGYSGLYEALES

ENSGT00510000046789_1_Linker_0_2 (140, 148)

WDFLKIEK

PF16739 // ENSGT00510000046789_1_Domain_2 (148, 237)

LEEHRLLLKRLQPELKAKIIPTDILPDISQCLI
PQECEEIRQIC---TNKGMIAGAEKLVECLQRSDKENWPKTLKLALEKE---GYDE

ENSGT00510000046789_1_Linker_2_3 (237, 307)

LWIV
DEGMKNMEKKAVE---DDEMEISSIQIFYQEEQECQ-NLSQNSSPPPDNSY---TNLYDP
LKPRNY

PF04851 // ENSGT00510000046789_1_Domain_3 (307, 478)

QLELALPAKKGKNTIICAPT-GCGKTFVSLLICEHHLK-KFPPGQ-GKVVFFAN
QIPVYEQQASVF------SRYFQRLGYRVVGISGATAENTPVKQTIENNDIIILTPQILV
NNLKNGTIPSVSVFTLMIFDECHHTNKHHPYNMIMFSYLDQKLGGASAPLPQIIGLT

ENSGT00510000046789_1_Linker_3_4 (478, 723)

ASV
GVGDAKTIEDATSYICKLCAALDVTVIATVRDNLEELEQVVYKPQKISRKVESRATNTFK
LIISQLMKETENLAKNVSVEL-----GKLFQIQNRQFGTQKYEQWIVAVHHACKVFQMAD
KEEESRVCKALFLYTSHLRKYNDALIINEDAQMKDALKYLKD-FFNNL------------
-----------REATFDEIEQD--LTRRFEEKLEELE-NVSMDPSNENPKLRD---LYLI
LQ

PF00271 // ENSGT00510000046789_1_Domain_4 (723, 832)

EEYHLNPDTKTILFVKTRALVDALKKWIEENSALSFLKPGILTGRGRTKQVTGMTLPA
QKCVLEAFRASSDNNILIATSVADEGIDIAECNLVILYEYVGNVIKMIQTRGLGGCIFAH
SPL---------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------

------------------------------------------------------------
--------------------------------------MEAATLFLKFLLELQEEGWFRG
FLDALDHAGYSGLYEAIESWDFKKIEKLEEYRLLLKRLQPEFKTRIIPTDIISDLSECLI
NQECEEILQIC---STKGMMAGAEKLVECLLRSDKENWPKTLKLALEKERN-KFSELWIV
EKGIKDVETEDLE---D-KMETSDIQIFYQEDPECQ-NLSENSCPPSEVCD---TNLCSP
FKSRNYQLELALPAM

PF04851 // ENSGT00510000046789_1_Domain_3 (316, 456)

KGKNTIICAPT-GCGKTFVSLLICEHHLK-KFPQGQKGKVVFFAN
QIPVYEQQKSVF------SKYFERHGYRVTGISGATAENVPVEQIVENNDIIILTPQILV
NNLKKGTIPSLSIFTLMIFDECHNTSKQHPYNMIM

ENSGT00510000046789_1_Linker_3_4 (456, 775)

FNYLDQKLGGSSGPLPQVIGLTASV
GVGDAKNTDEALDYICKLCASLDASVIATVKHNLEELEQVVYKPQKFFRKVESRISDTFK
YIIAQLMRDTESLAKRICKDL-----ENLSQIQNREFGTQKYEQWIVTVQKACMVFQMPD
KDEESRICKALFLYTSHLRKYNDALIINEHARMKDALDYLKD-FFSNV------------
-----------RAAGFDEIEQD--LTQRFEEKLQELE-SVSRDPSNENPKLED---LCFI
LQEEYHLNPETITILFVKTRALVDALKNWIEGNPKLSFLKPGILTGRGKTNQNT

PF00271 // ENSGT00510000046789_1_Domain_4 (775, 836)

GMTLPA
QKCILDAFKANGNHNILIATSVADEGIDIAQCNLVILYEYVGNVIKMIQTRGRGR

ENSGT00510000046789_1_Linker_4_5 (836, 911)

ARGSK
CFLLTSNAGVIEKEQINMYKEKMMNDSILRLQTWDEAVFREKILH---IQTHEKFIRDSQ
EN-PKPVPDK

PF11648 // ENSGT00510000046789_1_Domain_5 (911, 1032)

ENKKLLCRKCKALACYTADIRVIEECHYTVLGDAFKECFVSRPHPKPNKF
SSFEKRAKIFCARQNCSHDWGIHVKYKTFE-IPVIKIESFVVEDIATGVQTLYSKWKDFH
FEKIPFDPAEMSK--------------

-----------------------------------

PF16739 // ENSGT00510000046789_1_Domain_0 (36, 140)

MTAEQRQNLQAFRDYIKKILDP---
---TYILS-------YMNTWLEDGEVQYIQAEKNNKGPMEAASLFLQYLVKLQSEGWFQA
FLDALYHAGYCGLCEAIKS

ENSGT00510000046789_1_Linker_0_2 (140, 148)

WDFQKIEQ

PF16739 // ENSGT00510000046789_1_Domain_2 (148, 239)

LEEHRSLLRRLEPEFKATVDPKDILPEISECLI
NQEYEEIMQIR---HNKGRMASAEKMAQCLIRSDKENWPKVLQLALEKDDS-KFSELW

ENSGT00510000046789_1_Linker_2_3 (239, 307)

NV
DKGFKRAESKAVE---DDGAEASSIQIFIQEEPECQ-NLSQNPGPPSEAPS---NTSHSP
LKPRNY

PF00270 // ENSGT00510000046789_1_Domain_3 (307, 481)

QLELALPAKKGKNTIICAPT-GCGKTFVSLLICEHHLK-KFPCGQKGKVVFFAN
QIPVYEQQATVF------SRYFERLGYNIASISGATSDSVSVQHIIEGNDIIILTPQILV
NNLNNGAIPSLSVFTLMIFDECHNTSKNHPYNQIMFRYLDHKLGESPDPLPQVIGLTASV
GVGDAKTTEEAMQHICKLCAALDASVIATVRDNVAELEQVVYKPQKISRKVESRTSNTFK
CIISQLMKETEKLAKDVSEEL-----GKLFQIQNREFGTQRYEQWIVGVHKACSVFQMSD
KEEESRVCKALFLYTSHLRKYNDALIISEDAQMTDALNYLKA-FFHDV------------
-----------REAAFDETEQD--LTRRFEEKLEDLE-KVSRDPSNENPKLRD---LYLV
LQEEYHLKPETKTILFVKTRALVDALKKWIEENPALSFLKPGILTGRGRTNQAT------
---------------------------------------------------GRGRARDSK
CFLLTSSADVIEKEKANMVKEKIMNESILRLQTWDEMKFEKTVRR---IQLNEKLLRDSQ
HK-PQPVPDKENK

PF11648 // ENSGT00510000046789_1_Domain_5 (914, 1030)

KLLCGKCKTFACYTADIRVVETSHYTVLGNAFKEHFVCKPHPKPKIY
DSFEKKAKIFCAKQNCSHDWGIFVRYKTFE-IPVIKIESFVVEDIASGVQNRHSKWKDFH
FERIQFDPAEMSI--------------

-----------------------------------

PF16739 // ENSGT00510000046789_1_Domain_0 (36, 140)

MTTEQRRSLLAFQDYIRKTLDP---
---TYILS-------YMAPWFREEEVQYIQAEKNNKGPMEAATLFLKFLLELQEEGWFRG
FLDALDHAGYSGLYEAIES

ENSGT00510000046789_1_Linker_0_2 (140, 148)

WDFKKIEK

PF16739 // ENSGT00510000046789_1_Domain_2 (148, 240)

LEEYRLLLKRLQPEFKTRIIPTDIISDLSECLI
NQECEEILQIC---STKGTMAGAEKLVECLLRSDKENWPKTLKLALERERN-KFSELWT

ENSGT00510000046789_1_Linker_2_3 (240, 307)

V
EKGIKDVETEDLE---D-KMETSDIQIFYQEDPECQ-NLSENSCPPSEVSD---TNLHSP
FKLRNY

PF00270 // ENSGT00510000046789_1_Domain_3 (307, 481)

QLELALPAKKGKNTIICAPT-GCGKTLVSVLICEHHLK-KFPPGQKGKVVFFAN
QIPVYEQQQSVF------SKYFERLGYRVTGISGATAENVPVEQIVENNDIIILTPQILV
NNLKKGTIPSLSVFTLMIFDECHNTSKQHPYNMIMFNYLDQKLGGSSGPLPQVIGLTASV

ENSGT00510000046789_1_Linker_3_4 (481, 729)

GVGDAKDTDEALDYICKLCASLDASVIATVKDNLEELEQVVYKPQKFFRKVESRVSDKFK
CIIAQLMRDTESLAKRICKDL-----ESFSQIQNREFGTQKYEQWIVTVQKACMVFQMPD
KDEESRICKALFLYTSHLRKYNDALIISEDARVKDALDYLKD-FFSNV------------
-----------RAAGFDETEQD--LTQRFEEKLQELE-SVSRDPSNENPKLED---LRFI
LQEEYHLN

PF00271 // ENSGT00510000046789_1_Domain_4 (729, 836)

PETITILFVKTRALVDALKNWIEGNPKLSFLKPGILTGRGKTNQNTGMTLPA
QKCILDAFKVNGDHNILIATSVADEGIDIAQCNLVILYEYVGNVIKMIQTRGRGR

ENSGT00510000046789_1_Linker_4_5 (836, 914)

ARGSK
CFLLTSNAGVIEKEQINMYKEKMMNDSILRLQTWDEAVFREKILH---IQTHEKLIRDSQ
EK-PKPVPDKENK

PF11648 // ENSGT00510000046789_1_Domain_5 (914, 1030)

KLLCGKCKALVCYTADIRVIEECHYTVLGDAFKECFVRRPHPKPKKF
PNFDKREKIFCARQNCSHDWGIHVKYKTFE-IPVIKIESFVVEDIATGVQTLYSKWKDFH
FEKIPFDPAEMAK--------------

-----------------------------------MSAEDRQNLHAFRDYVVKTLDP---
---TYILS-------YMAPWFKDDKVQHIQAEKNNKGTTEAASLFLKFLLELQEEGWFRG
FLDALGHAGYSGLYEAIETWDFRKIESLEEYRLLLKRLQPEFKTTVNPKDILPEISGCLI
SQECEEIIQVC---SNKGLMAGAEKMAECLLRSDKENWPKTLKLALEIEES-QFSQLWIM
DKDAKNVEPKVLE---DDEIETSDIQIFYKEEPECQ-NLSQNPSPPSEGHQ---NSCHC

PF04851 // ENSGT00510000046789_1_Domain_3 (300, 482)

Q
LKPRNYQLELALPAKEGKNTIICAPT-GCGKTFVSLLICEHHLK-KFPQGQKGKVVFFAI
QLPVYEQQKSVF------SKYFEKLGYKVAGVSGATSEIVSVEEIVENYDIIILTPQILV
NSLRKGTVPSLSVFTLMIFDECHNTGKHHPYNMIMFNYLDQKLGGSSDPLPQVIGLTASV
G

ENSGT00510000046789_1_Linker_3_4 (482, 755)

TGDAKNTTEAMEYICKLCASLDTSVIATVKDNLEELEEIVYKPQKFFRKVKLRTTDRFK
CIISQLMRETESLAKKIFDELSTVTLENVFQIQNRNFGTQKYEQWILSVQKTCILFQLPD
KEEESRICKALYLYTSHLRKYNDALIINEHARMKDALDYLKD-FFANV------------
-----------RAAGFDEIEQH--LTWRFEEKLRELE-SVSMDPGNENPKLQD---LSFI
LQEEYHLNPESRTILFVKTRALVDALKKWIEENS

PF00271 // ENSGT00510000046789_1_Domain_4 (755, 837)

ELSFLKPGILTGRGKTNQNTGMTLPA
QKCALDAFRTDGDKKILIATSVADEGIDIAQCNLVILYEYVGNVIRMIQTRGRGRARGSK
CFLLTSNADVIEKEKINIHKEKMMNDSILRLQTWNEAVFKEKVLQ---IQIQEKLIRDSQ
GK-VERVPDKENKKLLCRKCKGFACYTADIRVVEDCHYTVVGDDFRKCYVSKLHPKPKSF
GYFEKTAKIFCSREDCSHDWGIHVKYKTFE-IPVIKIESFVVEDIATGAQKLYAKWRDFP
LQKIPFDAAEMSK--------------

-----------------------------------M

PF16739 // ENSGT00510000046789_1_Domain_0 (37, 140)

TSEQRRSLQAFQDYIRKTLDP---
---TYILS-------YMAPWFREEEVQYIQAEKNNKGPMEAATLFLKFLLELQEEGWFRG
FLDALDHAGYSGLYEAIES

ENSGT00510000046789_1_Linker_0_2 (140, 148)

WDFKKIEK

PF16739 // ENSGT00510000046789_1_Domain_2 (148, 238)

LEEYRLLLKRLQPEFKTRIIPTDIISDLSECLI
NQECEEILQIC---STKGMMAGAEKLVECLLRSDKENWPKTLKLALEKERN-KFSEL

ENSGT00510000046789_1_Linker_2_3 (238, 306)

WIV
EKGIKDVETEDLE---D-KMETSDIQIFYQEDPECQ-NLSENSCPPSEVSD---TNLYSP
FKPRN

PF00270 // ENSGT00510000046789_1_Domain_3 (306, 481)

YQLELALPAMKGKNTIICAPT-GCGKTFVSLLICEHHLK-KFPQGQKGKVVFFAN
QIPVYEQQKSVF------SKYFERHGYRVTGISGATAENVPVEQIVENNDIIILTPQILV
NNLKKGTIPSLSIFTLMIFDECHNTSKQHPYNMIMFNYLDQKLGGSSGPLPQVIGLTASV

ENSGT00510000046789_1_Linker_3_4 (481, 727)

GVGDAKNTDEALDYICKLCASLDASVIATVKHNLEELEQVVYKPQKFFRKVESRISDKFK
YIIAQLMRDTESLAKRICKDL-----ENLSQIQNREFGTQKYEQWIVTVQKACMVFQMPD
KDEESRICKALFLYTSHLRKYNDALIINEHARMKDALDYLKD-FFSNV------------
-----------RAAGFDEIEQD--LTQRFEEKLQELE-SVSRDPSNENPKLED---LCFI
LQEEYH

PF00271 // ENSGT00510000046789_1_Domain_4 (727, 836)

LNPETITILFVKTRALVDALKNWIEGNPKLSFLKPGILTGRGKTNQNTGMTLPA
QKCILDAFKASGDHNILIATSVADEGIDIAQCNLVILYEYVGNVIKMIQTRGRGR

ENSGT00510000046789_1_Linker_4_5 (836, 914)

ARGSK
CFLLTSNAGVIEKEQINMYKEKMMNDSILRLQTWDEAVFREKILH---IQTHEKFIRDSQ
EK-PKPVPDKENK

PF11648 // ENSGT00510000046789_1_Domain_5 (914, 1030)

KLLCRKCKALACYTADVRVIEECHYTVLGDAFKECFVSRPHPKPKQF
SSFEKRAKIFCARQNCSHDWGIHVKYKTFE-IPVIKIESFVVEDIATGVQTLYSKWKDFH
FEKIPFDPAEMSK--------------

-----------------------------------MTAEERRNLHAFRDYVTKILDP---
---TYILS-------YMSPWFKEDEVQYIQAEKNNKGVMEAATLFLKFLLELQEEGWFRG
FLDALHHAGYSGLYEAIESWDFHKIEKLEEHRSLLRRLQPEFKTRINPNDILPEVSECLI
NQECEEIRQVC---SNKGPMAGAEKMVECLLRSDKENWPKYLKLALEKEES-NFSELWII
EKGAKEE-TKELE---DGEIETSDVQIFYKEEPECQ-NLSQNSCPPSEASC-----TQSP
IKP

PF00270 // ENSGT00510000046789_1_Domain_3 (304, 488)

RNYQLELARPALEGKNTIICAPTEGCGKTFVALLICEHHLQ-KFPQGQKGKIVFFAN
QLPVYEQQKSVF------LKYFERHGYKIAGVSGATVENISVDQIVENNDIIILTPQILV
NSLKNGTIPSLSVFTLMIFDECHNTSKLHPYNVIMFHYLDQKLGGSSDPLPQVIGLTASV
GVGDAKN

ENSGT00510000046789_1_Linker_3_4 (488, 755)

TTEATEYICKLCASLDTSVVATVKDNLEELEEIVYKPQKFFRKVKSRTTNRFK
CIISELMKETESLAKSIFGELGTISLENLSQIQNRNYGTQKYEQWIVAVQKKCAVLHLPD
KDKESRICTALFLYTSHLRKFNDALLINEHARTKDALDYLKD-FFSNV------------
-----------RSAGFDEIEQD--LTRRFEEKLQELE-SISMDPSNENPKLKD---LCFI
LQEEYHLNPETRTILFVKTRALVDALKKWIEENS

PF00271 // ENSGT00510000046789_1_Domain_4 (755, 837)

ILSFLKPDILTGRGKTSQNIGMTLPA
QKCVLDAFRASGDKKILIATSVADEGIDIAQCNLVILYEYVGNVIKMIQTRGRGRARGSK
CFLLTSNDDVIEKEKINIYKEKMMNDSILSLQAWDETVFKKKIHQ---IQIHEKFIRDSQ
GK-AEPALDKKNKKLLCRKCKAFACHTADIRVIEECHYTVVGDAFKECFVTKAHPRPKSV
GIFEKKAKVFCARQNCSHDWGIHVKYKTFE-IPIIKIESFVVEDIATGEQRLYAKWRDFH
FEKLPFDPAEMS---------------

-----------------------------------MTAEQKANLQCYRQYIEKTLNP---
---AYVVG-------NMKEWLPDDVSERIQI--EQKGLTAAAQFFVDSLLQLESEGWFRG
FLDALHEAGYTGLREAIENWDFQKLENLEIHRQLLKRIEATLR-KIDTDQIIPLVYTCLI
DRECQEIKQVK---EHKGPMAGAVKLIECLCRSDKENWPKTFHLALDRAGYDEASKLWNM
KEGNDTDMDVEMM---DEQNRTLDINVQYSEEAEVH-NFSERPCSP--SEV-SEQPTYEP
KKA

PF04851 // ENSGT00510000046789_1_Domain_3 (304, 478)

RSYQIELAQPAISGKNTIICAPT-GSGKTFVSLLICDNHLR-NLSQDQKGKIVFLAT
KVPVYEQQKKVF------TQHFERTRYKVAGISGETAGDVSSARVIEGNDIIVLTPQILV
NSLKDGTIPSLAIFTLIIFDECHNTTGNHPYNVLMTSYLNLKYDSAAKQLPQIVGLT

ENSGT00510000046789_1_Linker_3_4 (478, 775)

ASV
GVGSAKTTEETIEYICTLCACLDIQVISTVRENTDELEKIVYKPKKSIRHVGNRPKNRFM
DIISVLMSETEALARKVYPI------DALSHIKTKSFGTQCYEQWIVDTQKKCRMLQLPD
KEEESRICRALFIYTEHLRKYNDTLIINEDARTCDALVYLTE-FFNDI------------
-----------RSGGFDETDQQ--LTANFEAKQQELK-AASEDELSENPKLEE---LTFI
LDEEYRLNPETRTILFVKTRALVAALKKWIDENPALSYLKPDTLMGRSKRNEQT

PF00271 // ENSGT00510000046789_1_Domain_4 (775, 837)

GMTLSN
QKGVLDSFRSNGDSKILIATAVADEGIDIAQCNLVLLYEYSGNVTKMIQVRGRGRA

ENSGT00510000046789_1_Linker_4_5 (837, 914)

KDSK
CILVTSKSEVVENERNNIYREEMMNQAIEQLQEWDEDRFARKISN---LQNKEKAMRDCR
KREKKQKPLGGNR

PF11648 // ENSGT00510000046789_1_Domain_5 (914, 1032)

ELLCGKCKTYVCNTEDIRVIAESHHTVVDAQFKERFITKPHKRPKRY
GQFEKKCKMHCQDAKCQHDWGITVKYMEFDDCPVIKIESFVVRDITTGKLSNFRRWKDVD
FAMKEFDTNEMLVILC-----------

-----------------------------------MTF

PF16739 // ENSGT00510000046789_1_Domain_0 (39, 140)

EQRRSLRAFRDYIRKTLDP---
---TYILS-------YMAPWFREEEVQYIQAEKNNKGPMEAATLFLKILLDLQEEGWFRG
FLDALDHAGYSGLYEAIES

ENSGT00510000046789_1_Linker_0_2 (140, 148)

WDFQKIEK

PF16739 // ENSGT00510000046789_1_Domain_2 (148, 236)

LEEYRLLLKRLQPEFKSRIIPTDILPDLSECLI
NQECEEITQIC---STKGMMAGAEKLVECLLRSDKENWPKTLKFALEKERN-QFS

ENSGT00510000046789_1_Linker_2_3 (236, 306)

ELWII
EKGIKDVETEDLE---E-KMETSDIQIFYQEDPECQ-NLSENSCLPSEVSD---TDLYSP
FKTRS

PF00270 // ENSGT00510000046789_1_Domain_3 (306, 481)

YQLELAVPAKKGKNTIICAPT-GCGKTFVALLICEHHLK-KFPQGQKGKVVFFAN
QIPVYEQQKSVF------SEYFERLGYRVTGISGATAENVPVKQIVENNDIIVLTPQILV
NNLKNGTIPSLSIFTLMIFDECHNTSKQHPYNMIMFNYLDQKLGGSSGPLPQVIGLTASV

ENSGT00510000046789_1_Linker_3_4 (481, 726)

GVGDAKDTGEALDYICKLCASLDASVIATVQDNLEELEQVVYKPQKFFRKVESRVSDKFK
CIIAQLMRETESLAKRICKDF-----ENLSKIQNREFGTQKYEQWIVTVQKACMVLQMPD
KEEESRICKALFLYTSHLRKYNDALIISEDARMKDALQYLKD-FFSNV------------
-----------RAARFDETEQD--LTQRFEEKLQELE-SVSRDPSNENPKLED---LCFI
LQEEY

PF00271 // ENSGT00510000046789_1_Domain_4 (726, 836)

HLNPETITILFVKTRALVDALKNWIEGNSKLSFLKPGILTGRSKTNQNTGMTLPA
QKCILDSFKAHGDHNILIATSVADEGIDIAQCNLVILYEYVGNVIKMIQTRGRGR

ENSGT00510000046789_1_Linker_4_5 (836, 914)

ARGSK
CFLLTSSAAVIEKENINMYKEKMMNDSILCLQKWDEAVFKEKILH---IQIDEKFIRDSQ
EK-TKPVPDKENK

PF11648 // ENSGT00510000046789_1_Domain_5 (914, 1031)

KLLCRKCKAFACYTADIRVIEESHYTVLGDAFKACFVSRPHPKPIQF
SNFYKRAKIFCARQDCSHDWGIHVKYKTFE-IPVIKIESFVVEDIATGVQTLYSKWKDFH
FEKIPFDAAEMSK--------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------IC---SNKGLMAGAEKMVECLLRSDKENWPKTLKPALEKEES-KFSELWMV
EKGAKDVKMKDLE---DDEMKTLDVQVFYREEPENQ-NLSQNSCPSSEVPH-----TYSP
LKP

PF00270 // ENSGT00510000046789_1_Domain_3 (304, 488)

RNYQLELALPAQKGKNTIMCAPT-GCGKTFVSLLICEHHLK-KFPQGQKGKAVFFAM
QLSVYGQQKSVF------SKYFGRLGYKVVGISGVTCDNVSVEQTVENNGIIILTPQILV
NNLKNGTIPSLSVF--MIFDECHNTSKHHPYNMIMFNCLDQKFGGSSDSLPQVIGLTASV
GTGDARN

ENSGT00510000046789_1_Linker_3_4 (488, 755)

TAEATEYICKLCASLATSVVA--KDNLEELEEIVYKPKKFFRKVESRTTNRFK
CNISQLMI--ESLVKSIFEEL-----ENLSHIPNRNFGTQRYEQWIIALQKACMVFQMPD
--EESRICKALFFYTSHLWRYNDALIINEHARMKDALDYLKD-FFRNV------------
-----------QAEGFDEIEQA--LTQRFEENLVDL---ISMDPMNDNPILKD---LCFI
L-EEYHLSPETRIILFVKTRALMDALKKRLEENP

PF00271 // ENSGT00510000046789_1_Domain_4 (755, 837)

KLSFLKPGILTGRGRTNQKIGMTLPV
QKCVLDAFRTDGDNKILIATSVADEGIVIAQCNLVLLYEYVGNVAKMIQTRGRGRARGSK
CFLLTSNADVIEKEKINIYEEKMMNDSILSLQT-DEAVFKEKVCQ---IQIHEKFIRDNQ
GK-VKPVLDKENKKLLCRKCKTFACYTADIRVMEECHFTMVGVAFREHFVSKLHPRPKSF
GSFEKRAKIFCAREDCSYDWGIHVKYKVFE-IPVIKTESFVVEDVATGVQTLYAKWKDFH
FEKIPFDAAEMST--------------

-----------------------------------M

PF16739 // ENSGT00510000046789_1_Domain_0 (37, 141)

TSEQRRNLLTFQDYVRKILDP---
---THILC-------YMAPWFREDKMQYIQAEKNNRGPMEAASLFLQFLLELQEEGWFRG
FLDALNQAGYSGLYEAIENW

ENSGT00510000046789_1_Linker_0_2 (141, 148)

DFNKIEK

PF16739 // ENSGT00510000046789_1_Domain_2 (148, 238)

LEVYRTLLKRLQPEFKNRIIPLEILPELAECLI
SQECEEIRQTC---YNKGMIAGSEKLIECLLKSDKENWPKVLKLALEKEQN-NLSEM

ENSGT00510000046789_1_Linker_2_3 (238, 314)

WLV
EKGEKDIENKDLE---DDEMETSEIHIFFQEDPEHQ-NLSQNSQAPSEMSR-------TN
LKPRNYQLELALP

PF04851 // ENSGT00510000046789_1_Domain_3 (314, 478)

AKEGKNTIICAPT-GCGKTLVSLLICEHHLK-NFPQGRKGKVAFFAN
HVPVYEQQKSVF------LSYFERLGYSVAGISGATTENVPVEQTIKNNDIIILTPQIIV
NNLKNGTIPSLSVFTLMIFDECHNTNKHHPYNMIMFNYLDQKLGGSSDPLPQVVGLT

ENSGT00510000046789_1_Linker_3_4 (478, 727)

ASV
GVGDAKTTDEAMLYICKLCASLDATVIATVRDNLEELEQVVYKPQKFSRKVESRTTNKFK
FIVSQLMRDIESLARNICAEF-----GNLFQTQNGDFGTQKYEQRIVGVHKAGMVFRLPD
KEEESRICKALFLYTSYLRKYNDSLIISEDAQMKDALNYLKD-FFNNV------------
-----------RTAGFDETEQD--LTWRFEEKLEELE-SVCRDPSNENPKLND---LCLI
LQEEYH

PF00271 // ENSGT00510000046789_1_Domain_4 (727, 836)

LYPETRTILFVKTRALVDALKKWIKENAALNFLKPGVLTGRGRTNQNTGMTLPA
QKCALDAFREDKD-NILIVTSVADEGIDIAQCNLVILYEYVGNVIKMIQTRGRGR

ENSGT00510000046789_1_Linker_4_5 (836, 914)

ARGSK
CYLLTSNADVIEKENINMYREEMMNDSISKLQTWDKTEFEKKVHS---IQIHDKFIRDSQ
PK-SKPVPDKKNK

PF11648 // ENSGT00510000046789_1_Domain_5 (914, 1031)

KLLCGKCKTLACYTADVRVVETCHYTVVGDDFKERFVRKPHPRPKNY
GGFEKKAKIFCAKESCRHDWGIHVKYKEFE-IPVIKIESFVVEDIATGVQTRYSKWKDFH
FEKIQFDAAEYPNDFRA----------

-----------------------------------

PF16739 // ENSGT00510000046789_1_Domain_0 (36, 140)

MTTEQRRSLLAFQDYIRKTLDP---
---TYILS-------YMAPWFREEEVQYIQAEKNNKGPMEAATLFLKFLLELQEEGWFRG
FLDALDHAGYSGLYEAIES

ENSGT00510000046789_1_Linker_0_2 (140, 148)

WDFKKIEK

PF16739 // ENSGT00510000046789_1_Domain_2 (148, 240)

LEEYRLLLKRLQPEFKTRIIPTDILSDLSECLI
NQECEEILQIC---STKGMMAGAEKLVECLLRSDKENWPKTLKLALERERN-KFSELWT

ENSGT00510000046789_1_Linker_2_3 (240, 307)

V
EKGIKDVETEDLE---D-KMETSDIQIFYQEDPECQ-NLSENSCPPSEVSD---TNLYSP
FKPRNY

PF00270 // ENSGT00510000046789_1_Domain_3 (307, 481)

QLELALPAKKGKNTIICAPT-GCGKTLVSVLICEHHLK-KFPPGQKGKVVFFAN
QIPVYEQQESVF------SKYFERLGYRVTGISGATAENVPVEQIVENNDIIILTPQILV
NNLKKGTIPSLSIFTLMIFDECHNTSKQHPYNMIMFNYLDQKLGGSSGPLPQVIGLTASV

ENSGT00510000046789_1_Linker_3_4 (481, 727)

GVGDAKDTDEALDYICKLCASLDASVIATVKDNLEELEQVVYKPQKFFRKVESRVSDKFK
CIIAQLMRDTESLAKSICKDL-----ESFSQIQNREFGTQKYEQWIVTVQKACMVFQMPD
KDEESRICKALFLYTSHLRKYNDALIISEHARVKDALDYLKD-FFSNV------------
-----------RAAGFDETEQD--LTQRFEEKLQELE-SVSRDPSNENPKLED---LCFI
LQEEYH

PF00271 // ENSGT00510000046789_1_Domain_4 (727, 836)

LNPETITILFVKTRALVDALKNWIEGNPKLSFLKPGILTGRGKTNQNTGMTLPA
QKCILDAFKVSGDHNILIATSVADEGIDIAQCNLVILYEYVGNVIKMIQTRGRGR

ENSGT00510000046789_1_Linker_4_5 (836, 914)

ARGSK
CFLLTSNAGVIEKEQINMYKEKMMNDSILRLQTWDEAVFREKILH---IQTHEKLIRDSQ
EK-PKPVPDKENK

PF11648 // ENSGT00510000046789_1_Domain_5 (914, 1030)

KLLCGKCKALVCYTADIRVIEECHYTVLGDAFKECFVSRPHPKPKKF
SNFDKRAKIFCARQNCSHDWGIHVKYKTFE-IPVIKIESFVVEDIATGVQTLYSKWKDFH
FEKIPFDPAEMAK--------------

------------------------------------------------------------
------------------------------------------------------------
LFDPFFPEGYTGLAEAIENWDFSKLEKLELHRQLLKRIEATML-EVDPVALIPYISTCLI
DRECEEIQQIS---ENRSKAAGITKLIECLCRSDKEHWPKSLQLALDTTGYYRASELWDI
REVFS--SGDEMT---DASEDCLEASMTYSEEAEPDDNLSENLGSAA-GIG-KPPPVYET
KKA

PF00270 // ENSGT00510000046789_1_Domain_3 (304, 488)

RSYQIELAQPAINGKNALICAPT-GSGKTFVSILICEHHFQ-NMPAGRKAKVVFLAT
KVPVYEQQKNVF------KHHFERQGYSVQGISGENFSNVSVEKVIEDSDIIVVTPQILV
NSFEDGTLTSLSIFTLMIFDECHNTTGNHPYNVLMTRYLEQKFNS-ASQLPQILGLTASV
GVGNAKN

ENSGT00510000046789_1_Linker_3_4 (488, 755)

IEETIEHICSLCSYLDIQAISTVRENIQELQRFMNKPEIDVRLVKRRIHNPFA
AIISNLMSETEALMRTIYSV------DTLSQNSKKDFGTQNYEHWIVVTQRKCRLLQLED
KEEESRICRALFICTEHLRKYNDALIISEDARIIDALSYLTE-FFTNV------------
-----------KNGPYTELEQH--LTAKFQEKEPELI-ALSKDETNENPKLEE---LVCI
LDDAYRYNPQTRTLLFAKTRALVSALKKCMEENP

PF00271 // ENSGT00510000046789_1_Domain_4 (755, 837)

ILNYIKPGVLMGRGRRDQTTGMTLPS
QKGVLDAFKTSKDNRLLIATSVADEGIDIVQCNLVVLYEYSGNVTKMIQVRGRGRAAGSK
CILVTSKTEVVENEKCNRYKEEMMNKAVEKIQKWDEETFAKKIHN---LQMKERVLRDSR
RKEIKPKVVEGQKNLLCGKCKAYACSTDDIRIIKDSHHIVLGEAFKERYTTKPHKKPMQF
DGFEKKSKMYCRNNNCQHDWGITVKYLTFDNLPVIKIKSFVMESTATGTQMDFQKWKSIN
SSLKNFDVEEMSN--------------

-----------------------------------MTTEQRLNLHAFGDYVRKTLDP---
---THILS-------YMAPWFREDEVQYIQAEKNNKGPMEAATLFLKLLLELQEEGWFRA
FLDALNQAGYSGLYEAIESWDFQKIEKLEDYRSLLKRLQPEFKARIIPTEILSEISECLI
NQECEEIIHVC---TNKGMMAGAEKMVECLLRSDKENWPKTLKLALEREQN-KFSELWII
DEGGQDFEIKDLE---DDDIETSEVQIFYQEDPESR-NLSQNAHPPSEISH---TDLYSP
FKPRNYQLELALPA

PF04851 // ENSGT00510000046789_1_Domain_3 (315, 478)

KKGKNTIICAPT-GCGKTFVSLLICEDHLK-KFSQGQRRKVVFFAN
QIPVYEQQKSVF------SKYFERLGYKVAGISGATAENAPVEQIVENNDIIFLTPQILV
NNLKNGTIPSLSVFTLMIFDECHNTSKQHPYNMIMFNYLDQKLGGSSDPLPQVIGMT

ENSGT00510000046789_1_Linker_3_4 (478, 777)

ASV
GVGDAKNTDEAMDYICRLCASLDVSEIVTVKDNLEELEQIVYKPQKYFRKVESRTTDPFK
CIISELMRETESLAKSICGEL-----ETLSPIQNREFGTQKYEQWISTVQKACTVFRLPD
RDEESRICKALFLYTSHLRKYNDALIINEHARMKDALDYLKD-FFSNV------------
-----------RAAGFDETEQD--LTRRFEEKLQELE-TISVDPNNENPKLED---LCFI
LQEEYHLNPETRTILFVKTRALVDALKKWIEGNSRLNFLKPDILTGRCKTNQNIGM

PF00271 // ENSGT00510000046789_1_Domain_4 (777, 836)

TLPA
QKCVLNTFGTNGANNILIATSVADEGIDIVQCNLVILYEYVGNVIKMIQTRGRGR

ENSGT00510000046789_1_Linker_4_5 (836, 912)

ARGSK
CFLLTSNADVIEKEKINLYKEKMMNDSILNLQAWNEAVFKRKILD---IQIHEKFLRDSQ
AK-PKPVLDKK

PF11648 // ENSGT00510000046789_1_Domain_5 (912, 1032)

NKKLLCKKCKALACYTADIRVIEDSHYTVVGDAFKERFVSKPHPKPKIF
SSFEKRAKIYCARQDCGHDWGIHVKYKTFE-IPVIKIESFVVEDIATGAQRLYSKWKEFH
FEKTPFHAVEMYK--------------

-----------------------------------

PF16739 // ENSGT00510000046789_1_Domain_0 (36, 141)

MTAEQRHNLQAYSDYVRKSLDP---
---THILS-------YMTPWLPENEVQSIQAEKNNKGPMEAASLFLRLLLELQVEGWFRG
FLDALNHAGYSGLYEAIENW

ENSGT00510000046789_1_Linker_0_2 (141, 148)

DFQNLEK

PF16739 // ENSGT00510000046789_1_Domain_2 (148, 231)

LEDYRTLLRRLEPEFKARIIPTEILPEIADCLI
TQDCEEIWQVC---TTKGPMAGAEKLAECLLRSDKGSWPKTLKLALEKDG

ENSGT00510000046789_1_Linker_2_3 (231, 314)

N-IFNDLWII
DEGMKDVESEELE---DNRMEHSDIQIFYQEDPEDQ-NLSQNSCPPSEVSH---TNLCSP
LKARNYQLELALP

PF04851 // ENSGT00510000046789_1_Domain_3 (314, 478)

AKEGKNTIICAPT-GCGKTFVSLLICEHHLL-KFPQGRKGKVVFFAN
HVPVYEQQKTVF------SRYFERLGYSVTGISGATAEKVPVAETIENNDIIVLTPQILV
NNLKNGTIPSLSVFTLMIFDECHNTSKHHPYNMIMFNYLDQKLGESSDPLPQVIGLT

ENSGT00510000046789_1_Linker_3_4 (478, 726)

ASV
GVGDAKNIEEAMAYICKLCASLDASVIATVKENLEELEQVVYKPQKISRKVEPRTTNKFK
LILCELMKETEYLAKSISEEL-----GYLFQIQDRVFGTQKYEQWIVAVHKACRLFQMPD
KEEESRICKAMYLYTSHLRKYNDTLIISEDAQMKDALNYLKD-FFSNV------------
-----------RTAAFDDIEQD--LTRRFEGEGC-----------FQNRKPLE---THLI
LQEEY

PF00271 // ENSGT00510000046789_1_Domain_4 (726, 836)

HLNPETRTILFVKTRALVDALKKWIEENSALNFLKPGILTGRGKTSNKTGMTLPA
QKCVLDTFRSNGD-NILIATSVADEGIDIAQCNLVILYEYVGNVIRMIQTRGRGR

ENSGT00510000046789_1_Linker_4_5 (836, 914)

AKGSK
CYLLSSNADVIEKEHINIIKEKMMNDSISRLQTWDEVTFQKRIYH---IQNQEKFIRDSQ
PK-SKFVPDKENK

PF11648 // ENSGT00510000046789_1_Domain_5 (914, 1031)

RLLCAKCKVLACYTADIRVIEESHYTVIGDAFKEHFVSKPHPKPLSY
GNFEKKEKIFCARQNCGHDWGIHVRYKTFE-IPVIKIESFVVEDIVTGLQKQYPRWKAFP
FKKIEFDATEMSK--------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------GPMVSVEKITECLLRSDKENWPKILKTALDMGDCDVVSKLWTL
DQDASGKQDIEVEGEQDEESGTFYVSGSYEEEPEKQ-NFSETLFSSAGVM----KTTYSP
QNAR

PF00270 // ENSGT00510000046789_1_Domain_3 (305, 480)

SYQMELAKPALVGKNTIICAPT-GCGKTFVAIMICKNHLQ-NMPNGQRGKVVFLVT
KVPVYEQQKAVF------IEQFERESYTVAGISGETAGNTPVEHVIKNSDIIVLTPQILV
NSLKNGTVPSLSMFTLMIFDECHNTDKSHPYNKIMINYLDNKLGTSACQLPQIVGLTAS

ENSGT00510000046789_1_Linker_3_4 (480, 775)

V
GVGDAKNKNEAIQHICKLCACLDAPIISTVRENLDDLEKIVFKPQKLFRKVETRRVNLFK
DIVSQLMAETEKLAKNVHSKT-----RCLFEVQNRSFGTQKYEQWIVNIQKICKVFQIPD
KEEERRICKTLFIYTSHLRKYNDALIIHEDARTTDALDYLED-FFNHV------------
-----------KSGEVDKIEQY--LIQRFEEKQQELK-NISRNEQNDNPKLKE---LCFL
LEEEYHLNPESRTILFVKTRALANALKRWIEENPKLDYLKSDVLMGRGKRNQAT

PF00271 // ENSGT00510000046789_1_Domain_4 (775, 837)

GMTLPL
QKDVLETFKASGETKVLIATSVADEGIDIAQCNVVILYEYIGNVIKMIQTRGRGRA

ENSGT00510000046789_1_Linker_4_5 (837, 913)

KDSK
CFLVSSKEELIEREKTNMIQEVMMNESILEMQKWDEGELVKRIHS---LQIQEKTIRDNK
TE-IIPEPEVNK

PF11648 // ENSGT00510000046789_1_Domain_5 (913, 1031)

WKLLCGKCKVLACYANDIRIVEESHHTVIGETFKNRFVAEPHPKQKRY
GNFEKIMKIYCKERECHHDWGIFVRYKIFE-MPIIKIESFVVEDIFTGAQHVCSKWKTFN
FVRIPFDAAEIST--------------

-----------------------------------MTAEERRNLHRVGEYVRKILDP---
---TYLLS-------YMAPWLREDVMQYIQAEKNNKGTTEAASLFLKFLLELKEEGWFRG
FLDALRHAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XX----XXXXX---XXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXX----XXXXX
XXXXXXXXXXXXX---XXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXVPHTS
LKPRNYQLELAFPANNGKNTLICAPT-GCGKTFVSILICEQHLKKKFPQGQKGKIIFFAA
QIPVYEQQKSVF------SKYFERLGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXYLDQKLGGSSDPLPQVVGLTASV
GVGDAKNTAEAMAHICKLCASLDTSVIATVKDNLKELEEVVYKPEKFFRKVEAQSTDKFK
CIISELMMEIQDMAKSVFEKLGTVTLENLFHIPNVNFGTQKYEQWIIAVQKACVVFQMPD
KNEESRICKALFLYTSHLRKYNDALIISEHARIKDALDYLED-FFTNV------------
-----------RAAGFDEIERH--LTQRFEAKLKELA-DISKDPSSENPKLRD---LCFI
LQEEYHVNPESRTILFVKTRALVDALKKWIEENP

PF00271 // ENSGT00510000046789_1_Domain_4 (755, 837)

ELSFLKPGILTGRGRTSQKVGMTLPA
QKCVLDTFRSDGDSKMLIATSVADEGIDIAQCNLVILYEYVGNVIKMIQTRGRGRAKDSK
CFLVTSNAEVIEKEKINMYQEKLMNESILKLQELDEAQFKRK------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------

-----------------------------------MTAEERRNLHAFRDYVIKTLDP---
---AYILS-------YMAPWFKDDEVQYIQAEKNNKGTMEAASLFLKCLLELQEEGWFRG
FLDALGHAGYSGLYEAIESWNFQKIESLEEYRLLLKRLQPEFKTTVNPNDILPKISECLI
SQECEEIIQIC---SNKGLMAGAEKMVECLLRSDKENWPKTLKLALETEES-KFSQLWIV
DKSHTDVELKVLE---DEEIETSEVQIFYKEEPECQ-NLSQDPCPPSEVAS-----TCTP
LKPRNYQLEL

PF00270 // ENSGT00510000046789_1_Domain_3 (311, 484)

ALPAKEGKNTIICAPT-GCGKTFVALLICEHHLK-KFPQGQKGKIVFFAI
QIPVYEQQNSVF------SKYFERLGYKVAGISGATSENISVEQIVENNDIIVLTPQILV
NCLRNGTIPSLSVFTLMIFDECHNTSKHHPYNMIMFNYLDQKLGGSSDPLPQVVGLTASV
GIG

ENSGT00510000046789_1_Linker_3_4 (484, 774)

DAKNTMEAMEYICKLCASLDTSVIATVKDNLEELEEIVYKPQKFFRKVESRTTDRFK
CIISQLMRETESLAKNIFDELGTITLENVSQIQNRNFGTQKYEQWIVSVQKACMVFQLPN
KDEESRICKALFLYTSHLRKYNDALIINEHARMKDALDYLKD-FFTDV------------
-----------RAAGFDEIEQH--LTYRFEEKLQELE-SISMDLSNENPKLKD---LSFI
LQEEYHLNPESRTILFVKTRALVDALKKWIEENSELSFLKPGILTGRGKTNHN

PF00271 // ENSGT00510000046789_1_Domain_4 (774, 836)

TGMTLPA
QKCALDAFRTDGDKKILIATSVADEGIDIAQCNLVILYEYVGNVIRMIQTRGRGR

ENSGT00510000046789_1_Linker_4_5 (836, 911)

ARGSK
CFLLTSNADVIKKEKLNIYKEKIMNDSILSLQMWNEAVFKEKVLQ---IQIQEKNIRDSQ
EK-VELVPDK

PF11648 // ENSGT00510000046789_1_Domain_5 (911, 1026)

ENKKLLCRKCKAFACYTADIRVVEECHYTVVGDAFTKCFVSKLHPKPKSF
GHFEKRAKIFCARRNCGHDWGIHVKYKTFE-IPVIKIESFVVEDIATGAQKLYAKWKDFP
FEKIPFGSPEIPE--------------

-----------------------------------MTAEERQNLRTVGAYVRRLLDP---
---TYILS-------YMAPWFKEEEMQSIQAEKNNKGTMEAASLFLKFLLELKEEGWFRG
FLDALNHAGYTGLYEAFESWDFQKLENLEEHRLLLRRLQPEFKARIIPTDILPEISQCLI
NQECEEIEQVC---SNKGMMAGAEKMVECLLRSDKENWPKILKLALEKEEC-QLSEIWTI
EKGENDVEVKDTE---MDEMETSYV-YSYQEEPEYQ-NLSQNSCPPSEVPH---INLYNP
LKPR

PF00270 // ENSGT00510000046789_1_Domain_3 (305, 480)

DYQLELALPAMKGKNTIICAPTEGCGKTFVSLLICEHHLK-NF--GQKGKVVFFAI
QIPVYEQQKSVF------SKHFERCGYRVAGISGATSESYPVEEIVANNDIIILTPQILV
NNLKNGIIPSLSVFTLMIFDECHNTSKHHPYNMIMFNYLDQKLGGSSGPLPQIIGLTAS

ENSGT00510000046789_1_Linker_3_4 (480, 775)

V
GIGNANNKCEAMDYICKLCASLDTSVIATVKDNLEELEQIVYKPQKFFRKVEARTNSKFK
CIISQLMKEIENLAESIFEELGTVTLENLSQIQNRTFGTQKYEQWIIAIQKACAVFHMPD
KEKESKICKALFLYTSHLRKYNDALIISEDAQIKDGLDYLKD-FFRNV------------
-----------QAAGFDETEQD--LTRRFEEKLQELE-DISMDPDNENPKLGD---LGFI
LKEEYHLNPETKTILFVKTRALADALKKWIQQNSNL-FLKPGILTGRGKTNQNT

PF00271 // ENSGT00510000046789_1_Domain_4 (775, 837)

GMTLPA
QKSVLDTFRTNGD-KILIATSVADEGIDIAQCNLVILYEYVGNVIKMIQTRGRGRA

ENSGT00510000046789_1_Linker_4_5 (837, 912)

KGSK
CFLLTSNADVIEKEKINMYKENLMNESISSLQTWDEAKFKDKIHQ---IQIQEKFFRESQ
EK-VEPEPDKK

PF11648 // ENSGT00510000046789_1_Domain_5 (912, 1032)

NKKLLCRKCKAFACYTADIRVVEESHYTVVGAAFKECFVRVPHPKPKQC
GSFEKREKIFCARQNCRHDWGICVRYKTFD-IPVIKIHSFVVEDIATGVQMAYDKWKDFH
PEKIPFDVGEMSK--------------

-----------------------------------

PF16739 // ENSGT00510000046789_1_Domain_0 (36, 141)

MTAEQRQNLQAFRDYVRKTLDP---
---TYILS-------YMSPWLQDDEVQYIQAEKNNKGPMEAASLFLQYLLQLQTDGWFQA
FLDALYHAGYCGLHEAIENW

ENSGT00510000046789_1_Linker_0_2 (141, 148)

DFQKIEK

PF16739 // ENSGT00510000046789_1_Domain_2 (148, 238)

LEEHRLLLRRLQPEFKARINPTDILSEMSECLI
NQECEEIRQIC---FTKGMMAGAEKMVECLLRSDKENWPKVLKFALEKEDN-KFSEL

ENSGT00510000046789_1_Linker_2_3 (238, 303)

WIV
DEGFKGLESKAVE---DDGMEISSIQIFIQEEPECQ-VLSQNPCLPSDESC---NNLHSS
LK

PF04851 // ENSGT00510000046789_1_Domain_3 (303, 478)

PRNYQLELALPAQKGKNTIICAPT-GCGKTFVSLLICEHHLR-SFPHGQKGKVVFFAN
QIPVYEQQETVF------SRHFERLGYSVAGVSGATTENVSVQHIIENYDIIILTPQILV
NSLNNGTIPSLSVFTLMIFDECHNTSKNHPYNQIMFRYLDHKLGQSPDPLPQVIGLT

ENSGT00510000046789_1_Linker_3_4 (478, 776)

ASV
GVGDAKTVDEAMLHICKLCAALHVSVIATTWKNWSRL--FISPRKVIFRKVESRTTNTFK
SIISQLMRETEKLAKNVSEEL-----GKSVLNHSEI-NL----IFCVCVPST--FSLVSF
QFNGEILSRLLFLYTSHLRKYNDALIISEDAQMKDALNYLKA-FFHDV------------
-----------REAAFDETEQD--LTRNFEGKGDLEV-A-GIW------GLDG---VWL-
-QK--NL----------IPMNTSVALKKWIEENPALSFLKPGILTGRGKTNQATG

PF00271 // ENSGT00510000046789_1_Domain_4 (776, 836)

MTLPA
QKYALEAFRASGDNNILIATSVADEGIDIAQCNLVILYEYVGNVIKMIQTRGRGR

ENSGT00510000046789_1_Linker_4_5 (836, 914)

ARDSK
CFLLTSNADVIEKEKANMFKEKIMNESISRLQAWDKIKFEEKVHH---IQMQEKLIRDSQ
HK-PQPVPDKENK

PF11648 // ENSGT00510000046789_1_Domain_5 (914, 1030)

KLLCGKCKAFACYTADVRVVEKSHYTVLGEAFKERFVSKPHPKPKIY
DSFEKKAKIFCAIQNCRHDWGIHVKYKTFE-IPVIKIESFVVEDIASGAQNRHSKWKDFR
FERIQFDPAEMSN--------------

-----------------------------------

PF16739 // ENSGT00510000046789_1_Domain_0 (36, 140)

MTTEQRRSLLAFQDYIRKTLDP---
---TYILS-------YMAPWFGEEEVQYIQAEKT-----------TRFLLELQEEGWFRG
FLDALDHAGYSGLYEAIES

ENSGT00510000046789_1_Linker_0_2 (140, 148)

WDFKKIEK

PF16739 // ENSGT00510000046789_1_Domain_2 (148, 240)

LEEYRLLLKRLQPEFKTRIIPTDILSDLSECLI
NQECEEILQIC---STKGMMAGAEKLVECLLRSDKENWPKTLKLALERERN-KFSELWT

ENSGT00510000046789_1_Linker_2_3 (240, 307)

V
ENGIKDVETEDLE---D-KMETSDIQIFYQEDPECQ-NLSENSCPPSEVSD---TNLYSP
FKPRNY

PF00270 // ENSGT00510000046789_1_Domain_3 (307, 481)

QLELALPAKKGKNTIICAPT-GCGKTLVSILICEHHLK-KFPQGQKGKVVFFAN
QIPLYEQQESIF------SKYFERLGYRVTGISGATAENVPVEQIVENNDIIILTPQILV
NNLKKGTIPSLSVFTLMIFDECHNTSKQHPYNMIMFNYLDQKLGGSSGPLPQVVGLTASV

ENSGT00510000046789_1_Linker_3_4 (481, 729)

GVGDAKDTDEALDYICKLCASLDASVIATVKDNLEELEQVVYKPQKFFRKVESRISDKFK
CIIAQLMRDTESLAKRICKDL-----ENFSQIQNREFGTQKYEQWIVTVQKACMVFQMPD
KDEESRICKALFLYTSHLRKYNDALIISEHARMKDALDYLKD-FFSNV------------
-----------RAAGFDEIEQD--LTQRFEEKLQELE-SVSRDPSNENPKLED---LRFI
LQEEYHLN

PF00271 // ENSGT00510000046789_1_Domain_4 (729, 836)

PETITILFVKTRALVDALKNWIEGNPKLSFLKPGILTGRGKTNQNTGMTLPA
QKCILDAFKVNGDHNILIATSVADEGIDIAHCNLVILYEYVGNVIKMIQTRGRGR

ENSGT00510000046789_1_Linker_4_5 (836, 914)

ARGSK
CFLLTSNAGVIEKEQINMYKEKMMNDSILRLQTWDEAVFREMILH---IQTHEKLIRDSQ
EK-PKPVPDKENK

PF11648 // ENSGT00510000046789_1_Domain_5 (914, 1030)

KLLCGKCKALVCYTADIRVIEECHYTVLGDAFKECFVSRPHPKPKKF
SNFEKRAKIFCARQNCSHDWGIHVKYKTFE-IPVIKIESFVVEDIATGVQTLYSKWKDFH
FEKIPFDPAEMSK--------------

------------------------------------------------------------
------------------------EVQHIQAEKNNKGPMEAASLFLQFLLELQEEGWFRA
FLDALNQAGYSGLYEAIESWDFQKIEKLEEYRSLLRRLQPEFKTTINPKDILPEISECLI
SQECEEIMQVC---SNKGLMAGAEKMVECLLRSDKENWPKTLKLALEKEES-KFSELWMV
ENGAKGVEMKDLE---DDEMKTFDVQIFYKEEPENQ-NLSQNSHPSSEAPH-----IYS

PF04851 // ENSGT00510000046789_1_Domain_3 (300, 482)

P
VKPRNYQLELALPAQKGKNTIICAPT-GCGKTFVSLLICEHHLK-KFPQGQKGKVVFFAV
QLPVYEQQKSVF------SQHFERLGYKVAGISGATSDNVSVEQIVENNDIIILTPQILV
NSLKNGTVPSLSVFTLMIFDECHNTSKHHPYNMIMFNYLDQKLGGSSDSLPQVVGLTASV
G

ENSGT00510000046789_1_Linker_3_4 (482, 753)

VGDARNTAEATEYLCQLCACLDTSVVATVKDNLEELEEMVYKPQKFFRKVKSRTANRFK
SVISQLMLETEGLAKSIFEEL-----ENLFHVQNREFGTQKYEQWIIAVQKVCMLFQMPD
KDEESRICQALFLYTSHLRXXXXXXXXXXXXXXXXXXXXXKD-FFTNV------------
-----------RAAGFDEIEQD--LTRRFEEKLQELE-SISMDPSNENPKLED---LCFI
LKEEYHINPETRTILFVKTRALVDALKRWIEE

PF00271 // ENSGT00510000046789_1_Domain_4 (753, 837)

SPTLSFLKPGILTGRGKTSQNTGMTLLA
QKCVLDTFRTNGDNKILIATSVADEGIDIAQCNLVILYEYVGNVIKMIQTRGRGRARGSK
CFLLTSD--DIEKEKINIYKEKMMNDSIVNVQTWDEAAFKEKIHQ---IQIHEKFIRDNQ
GK-AMPVPDKKNKKLLCRKCKAFACYTADIRVVEACHFTVIGDAFRERFVSKLHPRPKNY
GSFEKKAKIFCARPNCSHDWGIHVRYRAFE-IPVIKIESFVVEDVETGVQTLYARWRDFH
FEKIPFDAAEMSRC-------------

------------------------------------------------------------
------------------------------------GGGGGGALFLDAVLLLEAEGWLRG
FLDALVAAGYTGLAEAIENWDFSKLEKLELHRQLLKRIEATML-EVDPVAIMPYINTCLI
ERDCDEILQIS---EYRSKAAGITKLIECLCRSDKENWPKSLQLALDNAGYYNASELWNI
REENGKDVDGEMT---DASENYFETMVTFSEEAECD-NLSENLSSVSESTY-ESSSVYKP
KKA

PF04851 // ENSGT00510000046789_1_Domain_3 (304, 478)

RSYQIELAQPAIDGKNTMICAPT-GSGKTFVALMICEHHLQ-NVPSGQKAKVVFLAT
KVPVYEQQKNVF------RQHFERSGYSVQGICGETVANMSVENVIQDSDIIVLTPQILV
NSMEKGILSSLSIFTLMIFDECHNTTGNHPYNVLMTRYLDQKFDSSAKQLPQIVGLT

ENSGT00510000046789_1_Linker_3_4 (478, 775)

ASV
GVGSAKSTNETVEHICTLCSYLDIQAISTVRENKQDLQRFGNKPETHIRWVKMRAQNRFA
DIISGLMSETEVLMRKIYSV------DTISQINKNYLGTQRYEQWIVSTQKKCRLLQLED
KEKESSICRDLFICTEHLRKFNDALIISEDARIEDALAYLNE-FFTNV------------
-----------KNGPYTELEKQ--LTEKFQEKEPELT-ALSKDESNENPKLEE---LACI
LDEAYRYNPETRTILFAKTRALVAALKKWIEANPVLSHIKPDVLMGRARRDHKT

PF00271 // ENSGT00510000046789_1_Domain_4 (775, 836)

GMTLPM
QKGVLDAFRNDKDIRLLIATSVADEGIDITECNLVVLYEYFGNVTKMIQVRGRGR

ENSGT00510000046789_1_Linker_4_5 (836, 913)

ARDSK
CILVTSKTEVVENEKLNRYKEEMMNAAIEKLQNWDETTFARTICR---LQRREKVLRDSK
KNETKPEVLKGK

PF11648 // ENSGT00510000046789_1_Domain_5 (913, 1030)

KNLLCGKCKVYVCSTDDIRIIKESHHTVLGDTFKERYITKPHRKPVQF
DGFEKKSKMHCQNAECQHDWGITVKYKTFDNLPVIKIKSFVLEDIETGTQMDFQKWKSIN
LSLKNFDEETFRLQNGHPPV-------

-----------------------------------MTAEEKENLLRFRHYIQKTLNP---
---VYILS-------YMKDWLPDDMVEKIQGLKD--NPTTAAEIFLQSIVELTSDGWFRG
FLNALSAAGYTGLHHAIENWNFEMIENLAPHRALLNVIEPSLR-VVDPEQVFPHMTDCLR
DQEWEEIRQFM---NIPTLATLVLDTIICLLRIDKNVYLKTYSLHANNSEI-TFFILCAD
NDNGRDVEM---M-DEDENSHVIDINVQYSEEPESD-NLSASPCSPSKMLQ---ESIYVP
KEA

PF04851 // ENSGT00510000046789_1_Domain_3 (304, 478)

RNYQKELAQPALNGKHTIICAPT-GSGKTFVSVMICDHHLQ-KMPPGMKGKVVFLAT
KVPVYEQQKKVF------QEYFKRSGYKVSGICGDTVANSPVEMIVEGNDIIVMTPQILV
NCLNDGTLASLSLFTLMIFDECHNTIGNHPYHILMSKYLDLKFDQPTTPLPQIVGLT

ENSGT00510000046789_1_Linker_3_4 (478, 775)

ASL
GVGSAKNLNETIKYICEICASLNAEVISTVKENIQELEEIVYKPQKSIRLVQKRPQNCFV
DIILQMMSETEELARKVYAIGKNIELV-----RGIYLTT---------------------
----SSNLSDFFVYQEQLEKLQVASVVRELAVCKGLVQGTPGCFYHPVGGFSHVQSKQKW
LELHLKMFLFQFKCKFDKKNKQINVYNQFIKKTQIWNTYVIKGRKNPNPTLMTEVVLCSI
GSQSHHMYVVT---ERATSRFMQKALKNWIEESPQLQHLNPEVLMGRGKRNQKT

PF00271 // ENSGT00510000046789_1_Domain_4 (775, 837)

GMTLPN
QKGVLDSFKTTGDSKILIATSVADEGIDIAQCNLVLLYEYTGNVIKMIQVRGRGRA

ENSGT00510000046789_1_Linker_4_5 (837, 913)

KYSK
CILVTSKKEQEENERYNMMKEELMNKAIKEVQDWKEEVFAQKIRE---LQKTEKQLQDSK
KKEPQRRLLSGN

PF11648 // ENSGT00510000046789_1_Domain_5 (913, 1031)

RRLLCSKCKIFACDTDDIRVIEESHHTVIDENFIKRYITKPHEKPSCY
GNFEKRCKLHCA--KCQHDWGITVKYKAFDDLPIIKIDSFSVEDVSTGRQHYFRKWKNAN
FAMKEFDIEEM----------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------METSDVQIFYQEDPEYQ-NLSQNSC----------------
-----------------------PPS

PF04851 // ENSGT00510000046789_1_Domain_3 (327, 478)

-GCGKTFVSLLICEHHLE-KFSQGQKGKVVFLAN
QIPVYEQQKSVF------SKYFEKLGYRVTGISGETAENVPVEQIVENNDIVFLTPQILV
NNLKNGTIPSLSVFTLMIFDECHNTSKQHPYNMIMFNYLDQKLGGSLDPLPQVIGLT

ENSGT00510000046789_1_Linker_3_4 (478, 718)

ASV
GVGDAKNTDEAMDHICKLCASLDVSVIATVKENLEELEQIVYKPQKFFRKVESRTLDQFK
FIVSQLMRETECLAKSIHGDL-----GKLFQIQNREFGTQKYEQWIVTVQKACMVFQMPD
KDEERRICKALFLYTSHLRKYNDALIINEHARMKDALDYLKD-FFSNV------------
-----------RAAGFDEIEQD--LTWRFEGKLQELE-SVSMDPSKENPKLED---L

PF00271 // ENSGT00510000046789_1_Domain_4 (718, 836)

CFI
LQEEYHLNPETRTILFVKTRALVDALKKWIEGNSKLSFLKPGILTGRCRTNQNIGMTLPA
QKCILDAFRTSGDNNILIATSVADEGIDIAQCNLVILYEYVGNVIKMIQTRGRGR

ENSGT00510000046789_1_Linker_4_5 (836, 914)

ARGSK
CFLLTSNADVIEKEKINIYKEKMMNESILSLQTWDEAVFKEKILR---IQIHEKFIRDSQ
GK-AKPVLDKENK

PF11648 // ENSGT00510000046789_1_Domain_5 (914, 1031)

KLLCRKCKALACYTADVRVIEDSHYTVVGDAFKKCFVSKPHPKPKKF
CGFEKRAKIFCARQDCSHDWGIHVKYRTFE-IPVIKIESFVVEDVATGAQRLYSKWKDFH
FEKIPFDAAEMPRRL------------

-----------------------------------

PF16739 // ENSGT00510000046789_1_Domain_0 (36, 141)

MTAEQRQNLQAFRDYVRKTLDP---
---TYILS-------YMSPWLQDDEVQYIQAEKNNKGPMEAASLFLQYLLQLQTDGWFQA
FLDALYHAGYCGLHEAIENW

ENSGT00510000046789_1_Linker_0_2 (141, 148)

DFQKIEK

PF16739 // ENSGT00510000046789_1_Domain_2 (148, 238)

LEEHRLLLRRLQPEFKARINPTDILSEMSECLI
NQECEEIRQIC---FTKGMMAGAEKMVECLLRSDKENWPKVLKFALEKEDN-KFSEL

ENSGT00510000046789_1_Linker_2_3 (238, 303)

WIV
DEGFKGLESKAVE---DDGMEISSIQIFIQEEPECQ-VLSQNPCLPSDESC---NNLHSS
LK

PF04851 // ENSGT00510000046789_1_Domain_3 (303, 478)

PRNYQLELALPAQKGKNTIICAPT-GCGKTFVSLLICEHHLR-SFPHGQKGKVVFFAN
QIPVYEQQETVF------SRHFERLGYSVAGVSGATTENVSVQHIIENYDIIILTPQILV
NSLNNGTIPSLSVFTLMIFDECHNTSKNHPYNQIMFRYLDHKLGQSPDPLPQVIGLT

ENSGT00510000046789_1_Linker_3_4 (478, 722)

ASV
GVGDAKTVDEAMLHICKLCAALDVSVIATVRDNVEELEQVVYKPQKIFRKVESRTTNTFK
SIISQLMRETEKLAKNVSEEL-----GKLFQIQNREFGTQKYEQWIVDVHKACMVFQMAD
KEEESRICRVLFLYTSHLRKYNDALIISEDAQMKDALNYLKA-FFHDV------------
-----------REAAFDETEQD--LTRNFEEKLEELE-NVSMDPSNENPKLRD---LYLI
L

PF00271 // ENSGT00510000046789_1_Domain_4 (722, 836)

QEEYHLKPETKTILFVKTRALVDALKKWIEENPALSFLKPGILTGRGKTNQATGMTLPA
QKYALEAFRASGDNNILIATSVADEGIDIAQCNLVILYEYVGNVIKMIQTRGRGR

ENSGT00510000046789_1_Linker_4_5 (836, 914)

ARDSK
CFLLTSNADVIEKEKANMFKEKIMNESISRLQAWDKIKFEEKVHH---IQMQEKLIRDSQ
HK-PQPVPDKENK

PF11648 // ENSGT00510000046789_1_Domain_5 (914, 1030)

KLLCGKCKAFACYTADVRVVEKSHYTVLGEAFKERFVSKPHPKPKIY
DSFEKKAKIFCAIQNCRHDWGIHVKYKTFE-IPVIKIESFVVEDIASGAQNRHSKWKDFR
FERIQFDPAEMSN--------------

-----------------------------------

PF16739 // ENSGT00510000046789_1_Domain_0 (36, 140)

MTAEQRQNLQAFRDYIKKILDP---
---TYILS-------YMSSWLEDEEVQYIQAEKNNKGPMEAASLFLQYLLKLQSEGWFQA
FLDALYHAGYCGLCEAIES

ENSGT00510000046789_1_Linker_0_2 (140, 148)

WDFQKIEK

PF16739 // ENSGT00510000046789_1_Domain_2 (148, 238)

LEEHRLLLRRLEPEFKATVDPNDILSELSECLI
NQECEEIRQIR---DTKGRMAGAEKMAECLIRSDKENWPKVLQLALEKDNS-KFSEL

ENSGT00510000046789_1_Linker_2_3 (238, 313)

WIV
DKGFKRAESKADE---DDGAEASSIQIFIQEEPECQ-NLSQNPGPPSEASS---NNLHSP
LKPRNYQLELAL

PF04851 // ENSGT00510000046789_1_Domain_3 (313, 478)

PAKKGKNTIICAPT-GCGKTFVSLLICEHHLK-KFPCGQKGKVVFFAN
QIPVYEQQATVF------SRYFERLGYNIASISGATSDSVSVQHIIEDNDIIILTPQILV
NNLNNGAIPSLSVFTLMIFDECHNTSKNHPYNQIMFRYLDHKLGESRDPLPQVVGLT

ENSGT00510000046789_1_Linker_3_4 (478, 726)

ASV
GVGDAKTAEEAMQHICKLCAALDASVIATVRDNVAELEQVVYKPQKISRKVASRTSNTFK
CIISQLMKETEKLAKDVSEEL-----GKLFQIQNREFGTQKYEQWIVGVHKACSVFQMAD
KEEESRVCKALFLYTSHLRKYNDALIISEDAQMTDALNYLKA-FFHDV------------
-----------REAAFDETERE--LTRRFEEKLEELE-KVSRDPSNENPKLRD---LYLV
LQEEY

PF00271 // ENSGT00510000046789_1_Domain_4 (726, 836)

HLKPETKTILFVKTRALVDALKKWIEENPALSFLKPGILTGRGRTNRATGMTLPA
QKCVLEAFRASGDNNILIATSVADEGIDIAECNLVILYEYVGNVIKMIQTRGRGR

ENSGT00510000046789_1_Linker_4_5 (836, 914)

ARDSK
CFLLTSSADVIEKEKANMIKEKIMNESILRLQTWDEMKFGKTVHR---IQVNEKLLRDSQ
HK-PQPVPDKENK

PF11648 // ENSGT00510000046789_1_Domain_5 (914, 1030)

KLLCGKCKNFACYTADIRVVETSHYTVLGDAFKERFVCKPHPKPKIY
DNFEKKAKIFCAKQNCSHDWGIFVRYKTFE-IPVIKIESFVVEDIVSGVQNRHSKWKDFH
FERIQFDPAEMSV--------------

-----------------------------------MTAEEKQNLRFYRRYIERSLNP---
---VYILS-------NMTEWLSDEMEERVRKE-EEKGVTAAAALFLDAVLLLEAEGWFRG
FQDALAAAGYTGLAEAIENWDFGKLEKLELHRQLLKRIESTML-EIDPVAIMPYINTCLI
ERECDEILQVC---EYRSKAAGITKLIECLCRSDKENWPKSLQLALDSAGYYNASELWNI
REDNGKDVDGEMT---DASENNFETIMTFSEEAECD-NLSKNLSSVSEC---SSSSVYEP
KKA

PF04851 // ENSGT00510000046789_1_Domain_3 (304, 478)

RSYQIELAQPAIDGKNTLICAPT-GSGKTFVAVLICEHHFQ-NIPSGRKAKVVFLAT
KMPVYEQQKNVF------RQHFERSGYFVQGICGETVANISVENVIQDSDIIVLTPQILV
NIMDKGILSSLSIFTLMIFDECHNTAGNHPYNVLMTRYLDQKFDSSAKQLPQIVGLT

ENSGT00510000046789_1_Linker_3_4 (478, 770)

ASV
GVGNAKSTKETVEHICTLCSYLDIQAISTVRENKQDLQRFANKPEIHIRWVKMRAQNRFA
DIISGLMSETEVLMRKIYSV------DTISQINKIYFGTQRYEHWIVSTQKKCRLLQLED
KEKESSICRDLFICTEHLRKFNDALIISEDARIEDALAYLNE-FFTNV------------
-----------KNGPYTELEKQ--LTEKFQEIEQELT-ALSKDESNENPKLEE---LACI
LDEAYHYNPQTRTILFAKTRALVAALKKWVEANPLLSHIKPDVMMDLKY

PF00271 // ENSGT00510000046789_1_Domain_4 (770, 837)

YIGTVGMTLPM
QKGVLDAFRNDKDIRLLIATSVADEGIDITECNLVVLYEYFGNVTKMIQVRGRGRA

ENSGT00510000046789_1_Linker_4_5 (837, 913)

KDSK
CILVTSKTEVVENEKLNTYKEEMMNAAIEKLQNWDETTFARKIRG---LQMKEKMLRDSR
KNETKHELVEGK

PF11648 // ENSGT00510000046789_1_Domain_5 (913, 1016)

KKLYCGKCKAYACSTDDIRIIKGSHHIVLGNAFQERYTTKPHRKPVQF
DDFVKKSKMHCRNTECQHDWGIIVKYKIFDNLPVIKIRSFVLEDVESGSQMDFQKWR---
---------------------------

------------------------------------------------------------
--------------------------------------

PF16739 // ENSGT00510000046789_1_Domain_1 (99, 140)

MEAASLFLKLLLEVQVEGWFRG
FLDALNHAGYSGLYEAIES

ENSGT00510000046789_1_Linker_1_2 (140, 148)

WDFQNLEK

PF16739 // ENSGT00510000046789_1_Domain_2 (148, 231)

LEDHRTLLRRLEPEFKARVIPTEILPEIAECLI
AQDCEEIWQVC---ASKGPMAGAEKLAECLLRSDKENWPKALKLALERNG

ENSGT00510000046789_1_Linker_2_3 (231, 314)

N-IFSELWII
DEGVKDVEMKVIE---DDSMENSEVQIFYREDPEEQ-SLSQSPCPPAEMPS---TNLYSP
LKPRNYQLELAFP

PF04851 // ENSGT00510000046789_1_Domain_3 (314, 478)

AKEGKNTIICAPT-GCGKTFVSLLICEHHLQ-KFSQGRKGKVVFFAN
HVPVYEQQKTVF------SRHFDRLGYRVTGISGATAENVPVAQTIENSDIIVLTPQILV
NNLKNGTVPSLSVFTLMIFDECHNTSKHHPYNVIMFNYLDQKLGGFSDPLPQVIGLT

ENSGT00510000046789_1_Linker_3_4 (478, 726)

ASV
GVGDAGNVEEAMAHICKLCASLDASVIATVRENLEELEQVVSKPQKISRKVEPRTTNRFK
LILCQLMQETEHLAENVSEEL-----GYLFRIQDRVFGTQKYEQWIVAVHKACMVFRAPD
REEESRICKAMYLYTSHLRKYNDTLIISEDAQIKDALNYLKD-FFNNV------------
-----------RAAAFDETEQD--LTRRFEEKLPELE-RVCMDPSNENPKLRD---LHLI
LQEEY

PF00271 // ENSGT00510000046789_1_Domain_4 (726, 836)

HLNPETRTILFVKTRALVDALKKWIEENPALNFLKPGILTGRGKTNDKTGMTLPA
QKCVLDTFRANGD-NILIATSVADEGIDIAQCNLVILYEYVGNVIRMIQTRGRGR

ENSGT00510000046789_1_Linker_4_5 (836, 914)

AKGSK
CYLLSSNADVIAKENINLYKEQMMNDSISRLQTWDEAIFQERIHR---IQNQEKLIRDSQ
PK-PELVPDKENK

PF11648 // ENSGT00510000046789_1_Domain_5 (914, 1030)

RLLCGKCKVLACHTADIRVIEESHYTVIGDAFKKCFVRKPHPKPRSY
GGFEKKEKIFCARENCGHDWGIRVRYKTFE-IPVIKIESFVVEDTVTGLQKQYPRWKDFP
LEKIQFDAKELSQ--------------

-----------------------------------

PF16739 // ENSGT00510000046789_1_Domain_0 (36, 131)

MTAEQRQNLQAFGDYVRKTLDP---
---TYILS-------YMSPWLQDDEVQYIQAEKNNKGPMEAASLFLRYLLQLQTDGWFQA
FLDALYHAD-

ENSGT00510000046789_1_Linker_0_2 (131, 188)

SGLRAIETKWSLQKVEGGTKEINYT------------------SSVKAEL
TDHCICL

PF16739 // ENSGT00510000046789_1_Domain_2 (188, 231)

AQIC---FTKGMMAGAEKMVECLLRSDKENWPKVLKFALEKED

ENSGT00510000046789_1_Linker_2_3 (231, 300)

N-KFGDLWIV
DEGSKRLESKAVE--DDDGMEMSSIQIFIQEEPECQ-DLSQNPCLPSEESC---NNLHS

PF04851 // ENSGT00510000046789_1_Domain_3 (300, 478)

S
LKPRNYQLELALPAQKGKNTLICAPT-GCGKTFVSLLICEHHLK-KFPHGQKGKVVFFAN
QIPVYEQQATVF------SRHFERLGYSVAGVSGATTENVSVQHIIENNDIIILTPQILV
NSLNNGTIPSLSVFTLMIFDECHNTSKHHPYNQIMFRYLDQKLGQSPDPLPQVIGLT

ENSGT00510000046789_1_Linker_3_4 (478, 722)

ASV
GVGDAKTVDEAMFHICRLCAALDVSVIATVRDNAEELEQVVYKPQKVFRKVESRTANTFK
SIISQLMRETEKLAKNASEEL-----GKLFQIQNREFGTQKYEQWIVAVHKACMVFQMPD
KEEESRICRALFLYTSHLRKYNDALIISEDAQMKDALNYLKA-FFHDV------------
-----------REAAFDETEQD--LTRNFEEKLEELE-KVSMDPSNENPKLRD---LYLI
L

PF00271 // ENSGT00510000046789_1_Domain_4 (722, 836)

QEEYHLKPETKTILFVKTRALVDALKKWIEENPALGFLKPGILTGRGKTNQTTGMTLPA
QKCVLEAFRTSGDNNILIATSVADEGIDIAQCNLVILYEYVGNVVKMIQTRGRGR

ENSGT00510000046789_1_Linker_4_5 (836, 914)

ARDSK
CFLLTSSADVIEKEKANMFKEKIMNESISRLQAWDEMQFEKKVHQ---IQLDEKFIRDSQ
HK-PQPAPDKENK

PF11648 // ENSGT00510000046789_1_Domain_5 (914, 1030)

KLLCGKCKAFACYTADIRVVEKSHYTVVGKAFKERFVSKPHPKPKVY
DGFKKDAKIFCAIQNCCHDWGIQVKYKMFE-IPVIKIESFVVEDIASGAQNRHSKWKDFH
FERIQFDPAEMSN--------------

-----------------------------------MTAEQRRNLHAFRGYVSKILDP---
---TYILS-------YMTPWFRDDVVQRIQAEKNNKGPMEAASLFLQVLLELQEEGWFRG
FLDALHQAGYSGLCEAIESWDFQKIEKLEEYRLLLKRLQPEFKTTINPKDILPEISGCLI
SQECEEIIQIS---SNKGLMAGAEKMTECLLRSDKENWPKTLKLALEKEES-KFSELWMV
EKGAENVQMKDLE---DDEMKTLDIQIVYKEEPENQ-NLSQNPCPSSEVPP-----AYSP
LKPRNFQL

PF00270 // ENSGT00510000046789_1_Domain_3 (309, 480)

ELALPAQKGKNTIICAPT-GCGKTFVALLICEHHLK-QFPQGRKGKVVFFAV
QLPLYEQQKSAF------SEYFERLGYKVSGISGEIADSVSVEQIVENNDIIILTPQILV
NSLKDGTIPSLSIFTLMIFDECHNTNKNHPYNMIMFNYLDQKLGGSSDSLPQVVGLTAS

ENSGT00510000046789_1_Linker_3_4 (480, 775)

V
GVGDAKNEAEATEYICRLCASLDTSVLTTVRDNLEELEEVFYKPQKLFRKVESRTTDKFK
CVISQLMAETEALAKSIFEELGTVTLENLSRIQNRNFGTQKYEQWIIAVQKACMVFQMPD
KDEESRICKALFLYTSHLRKYNDALIISEDARMKDALNYLKN-FFSNV------------
-----------RAAGFDAIEQD--LTQRFEEKLVELE-DISVDPSNENPKLKD---LCFI
LQEEYHLNPETRTILFVKTRALVDALKKWIEENPKLSLLKPCILTGRGRTNQTM

PF00271 // ENSGT00510000046789_1_Domain_4 (775, 836)

GMTLPA
QKCALDAFRTNRDSKILIATSVADEGIDIAQCNLVILYEYVGNVIKMIQTRGRGR

ENSGT00510000046789_1_Linker_4_5 (836, 912)

ARGSK
CFLLTSNADVIEKEQLNICKEKMMNDSISSLQRWNEAVFKEKIHQ---IQVQEKLIRDNQ
GK-VKPVVDKN

PF11648 // ENSGT00510000046789_1_Domain_5 (912, 1033)

NKKLLCGKCKTFACYTADIRVVEECHFTVVRDAFRECFVTKSHPSPKKF
GNFEKKSKIFCARKDCLHDWGIHMTYRTFE-IPVIKIGSFVVEDVATGAQTLYSKWKDFN
FEKIPFDAAEMSAGAQDLNLQAMNGLE

-----------------------------------

PF16739 // ENSGT00510000046789_1_Domain_0 (36, 140)

MTTEQRRSLLAFQDYIRKTLDP---
---TYILS-------YMAPWFREEEVQYIQAEKNNKGPMEAATLFLKFLLELQEEGWFRG
FLDALDHAGYSGLYEAIES

ENSGT00510000046789_1_Linker_0_2 (140, 148)

WDFKKIEK

PF16739 // ENSGT00510000046789_1_Domain_2 (148, 240)

LEEYRLLLKRLQPEFKTRIIPTDILSDLSECLI
NQECEEILQIC---STKGMMAGAEKLVECLLRSDKENWPKTLKLALERERN-KFSELWT

ENSGT00510000046789_1_Linker_2_3 (240, 307)

V
EKGIKDVETEDLE---D-KMETSDIQIFYQEDPECQ-NLSENSCPPSEVSD---TNLYSP
FKLRNY

PF00270 // ENSGT00510000046789_1_Domain_3 (307, 481)

QLELALPAKKGKNTIICAPT-GCGKTLVSVLICEHHLK-KFPPGQKGKVVFFAN
QIPVYEQQESVF------SKYFERLGYRVTGISGATAENVPVEQIVENNDIIILTPQILV
NNLKKGTIPSLSVFTLMIFDECHNTSKQHPYNMIMFNYLDQKLGGSSGPLPQVIGLTASV

ENSGT00510000046789_1_Linker_3_4 (481, 729)

GVGDAKDTDEALDYICKLCASLDASVIATVKDNLEELEQVVYKPQKFFRKVESRVSDKFK
CIIAQLMRDTESLAKRICKDL-----ESFSQIQNREFGTQKYEQWIVTVQKACMVFQMPD
KDEESRICKALFLYTSHLRKYNDALIISEHARVKDALDYLKD-FFSNV------------
-----------RAAGFDETEQD--LTQRFEEKLQELE-SVSRDPSNENPKLED---LRFI
LQEEYHLN

PF00271 // ENSGT00510000046789_1_Domain_4 (729, 836)

PETITILFVKTRALVDALKNWIEGNPKLSFLKPGILTGRGKTNQNTGMTLPA
QKCILDAFKVNGDHNILIATSVADEGIDIAQCNLVILYEYVGNVIKMIQTRGRGR

ENSGT00510000046789_1_Linker_4_5 (836, 914)

ARGSK
CFLLTSNAGVIEKEQINMYKEKMMNDSILRLQTWDEAVFREKILH---IQTHEKLIRDSQ
EK-PKPVPDKENK

PF11648 // ENSGT00510000046789_1_Domain_5 (914, 1030)

KLLCGKCKALVCYTADIRVIEECHYTVLGDAFKECFVRRPHPKPKKF
PNFDKREKIFCARQNCSHDWGIHVKYKTFE-IPVIKIESFVVEDIATGVQTLYSKWKDFH
FEKIPFDPAEMAK--------------

-----------------------------------MTAEQRRNLHAFRDYVRKILDP---
---TYILS-------YMTPWFRDDVVQHIQAKKNNKGPMEAASLFLQVLLELQEEGWFRG
FLDALQQAGYSGLYEAIESWDFQKLEKLEEYRLLLKRLQPEFKTTINPEDILPEISGCLL
NQECEEIIQIS---SNKGLMAGAEKMVECLLRSDKENWPKTLKLALEKEES-KFSELWMV
EKGAENVQMKDLE---DDEMKTLDVHIVYKEEPESQ-NLSQNSCS-SEVPP-----TYSP
LKPRNY

PF00270 // ENSGT00510000046789_1_Domain_3 (307, 481)

QLELALPAQKGKNTIICAPT-GCGKTFVSLLICEHHLK-KFPQGRKGKVVVFAV
QVPLYEQQKSVF------SEYFERFGYKVSGISGETADNISVEQIVENNDIIILTPQILV
NSLKDGTIPSLSIFTLMIFDECHNTNKHHPYNMIMFHYLDQKLGGSSDSLPQVIGLTASV

ENSGT00510000046789_1_Linker_3_4 (481, 775)

GVGDAKNTAEATEYICKLCASLDTAVVTTVRDNLEELEEVVYKPQKFFRKVESRTTDRFK
RIISQLMAETEALAKSIFEELGTVTLENLSRIQNRNFGTQKYEQWIIAVQKACMVFQMPD
KEEESRICKALFLYTSHLRKYNDALIINEDARMKDALNYLKN-FFKNV------------
-----------RAAGFDAIEQD--LTQRFEEKLLELE-GISMDPSNENAKLKD---LCFI
LQEEYHLNPETRTILFVKTRALFQALKNWIEENPKLSFLKPGILTGRGRTNQTM

PF00271 // ENSGT00510000046789_1_Domain_4 (775, 836)

GMTLPA
QKCALDAFRTNRDSKILIATSVADEGIDIAQCNLVILYEYVGNVIKMIQTRGRGR

ENSGT00510000046789_1_Linker_4_5 (836, 912)

ARGSK
CFLLTSNADVIEKEKLNICQEKMMNESISRLQGWNEAVFKEKIRQ---IQIQEKLIRDSQ
GK-VKPVVDKK

PF11648 // ENSGT00510000046789_1_Domain_5 (912, 1032)

NKKLLCGKCKTFACYTADIRVVEECHFTVVRDAFRECFVTKLHPRPKKF
GSFDKKAKIFCARKDCLHDWGIHMKYKTFE-IPVIKIESFVVEDVATGAQTLYAKWKDFN
FEKIPFDAAEMSPWAQDLNLQGVDGLE

-----------------------------------

PF16739 // ENSGT00510000046789_1_Domain_0 (36, 141)

MTAEQRHNLQAFSDYVRKSLDP---
---THILS-------YMTPWLREDEVQYIQAEKNNKGPMEAASLFLKLLLELQVEGWFRG
FLDALNHAGYSGLYEAIENW

ENSGT00510000046789_1_Linker_0_2 (141, 148)

NFQNLEK

PF16739 // ENSGT00510000046789_1_Domain_2 (148, 231)

LEDHRTLLRRLEPEFKARIIPTEILPELAECLI
TQDYEEIWQVC---TNKGPMAGAEKMAECLLRSDKENWPKTLKLALEKDG

ENSGT00510000046789_1_Linker_2_3 (231, 306)

N-IFNELWII
DEGMKAVEMKNVE---DDRMENSDIQIFYREDPEDQ-NLSQNSCPPSEVSH---TNLYNP
LKPRN

PF00270 // ENSGT00510000046789_1_Domain_3 (306, 480)

YQLELARPAQEGKNTIICAPT-GCGKTFVSLLICKHHLL-TSPQGRKGKVVFFAN
HVPVYEQQKTVF------SRYFERLGYRVAGISGATAENVPVAQTIENNDIIILTPQILV
NNLKNGTIPSLSLFTLMIFDECHNTSKNHPYNMIMFSYLDQKLGGFPDRLPQVIGLTAS

ENSGT00510000046789_1_Linker_3_4 (480, 726)

V
GVGDAKNTEEAMAYICKLCASLDASVIATVKENVEELEQVVYKPQK--------------
--------------------------SYLFQVQDRVFGTQKYEQRIVAVHKACRVFRMPD
KEEESRICKAMYLYTSHLRKYNDTLIISEDAQMKDALNYLKD-FFNNV------------
-----------RAAAFGEIEQE--LTRRFEEKLPELE-SVSLDPSNENPKLKD---LHLI
LQEEY

PF00271 // ENSGT00510000046789_1_Domain_4 (726, 836)

HLNPETRTILFVKTRALVDALKKWIEENSALNFLKPGILTGRGKTNNKTGMTLPA
QKCVLDTFRASGD-NILIATSVADEGIDIAQCNLVILYEYVGNVIRMIQTRGRGR

ENSGT00510000046789_1_Linker_4_5 (836, 914)

AKGSK
CYLLSSNADVIEKEDINLYKEKMMNDSISRLQTWDETVFQERIHH---IQNQEKLIRDSQ
LK-PELVPDKQIK

PF11648 // ENSGT00510000046789_1_Domain_5 (914, 1031)

RLLCGKCKVLACNTADIRVIEESHYTVIGDDFKKRFVSKPHPKPRSY
GGFEKKEKIFCARQDCGHDWGIHVRYKTFE-IPVIKIESFVVEDITTGLQQHYPKWKDFP
LEKIQFDAKEMSK--------------

-----------------------------------

PF16739 // ENSGT00510000046789_1_Domain_0 (36, 140)

MTAEQRRNLHAFRGYVSKILDP---
---TYILS-------YMTPWFRDDVVQHIQAEKNNKGPMEAASLFLQVLLELQEEGWFRG
FLDALHQAGYSGLCEAIES

ENSGT00510000046789_1_Linker_0_2 (140, 148)

WDFQKIEK

PF16739 // ENSGT00510000046789_1_Domain_2 (148, 239)

LEEYRLLLKRLQPEFKTTINPKDILPEISGCLI
SQECEEIIQIS---SNKGLMAGAEKMIECLLRSDKENWPKTLKLALEKEES-KFSELW

ENSGT00510000046789_1_Linker_2_3 (239, 315)

MV
EKGAENVQMKDLE---DDEMKTLDIQIVYKEEPENQ-NLSQNPCPSS-VPP-----AYSP
LKPRNFQLELALPA

PF04851 // ENSGT00510000046789_1_Domain_3 (315, 478)

QKGKNTIICAPT-GCGKTFVALLICEHHLK-QFPQGRKGKVVFFAV
QLPLYEQQKSAF------SEYFERLGYKVSGISGEIADSVSVEQIVENNDIIILTPQILV
NSLKDGTIPSLSIFTLMIFDECHNTNKNHPYNMIMFNYLDQKLGGSSDSLPQVVGLT

ENSGT00510000046789_1_Linker_3_4 (478, 720)

ASV
GVGDAKNEAEATEYICRLCASLDTSVLTTVRDNLEELEEVFYKPQKFFRKVESRTTDKFK
CVISQLMAETEALAKSIFEELGTVTLENLSRIQNRNFGTQKYEQWIIAVQKACMVFQMPD
KDEESRICKALFLYTSHLRKYNDALIISEDARMKDALNYLKN-FFSNV------------
-----------RAAGFDAIEQD--LTQRFEEKLVELE-DISVDPSNENPKLKD---LCF

PF00271 // ENSGT00510000046789_1_Domain_4 (720, 836)

I
LQEEYHLNRETRTILFVKTRALVDALKKWIEENPKLSFLKPCILTGRGRTNQTMGMTLPA
QKCALDAFRTNRDSKILIATSVADEGIDIAQCNLVILYEYVGNVIKMIQTRGRGR

ENSGT00510000046789_1_Linker_4_5 (836, 914)

ARGSK
CFLLTSNADVIEKEQLNICKEKMMNDSISSLQRWNEAVFKEKIHQ---IQVQEKLIRDNQ
GK-VKPVVDKNNK

PF11648 // ENSGT00510000046789_1_Domain_5 (914, 1031)

KLLCGKCKTFACYTADIRVVEECHFTVVRDAFRECFVTKSHPKPKKF
GNFEKKSKIFCARKDCLHDWGIHMTYKTFE-IPVIKIESFVVEDVATGAQTLYSKWKDFN
FEKIPFDAAEMSAGAQDLNLQAMNGLE

-----------------------------------

PF16739 // ENSGT00510000046789_1_Domain_0 (36, 140)

MTTEQRRSLLAFQDYIRKTLDP---
---TYILS-------YMAPWFREEEVQYIQAEKNNKGPMEAATLFLKFLLELQEEGWFRG
FLDALDHAGYSGLYEAIES

ENSGT00510000046789_1_Linker_0_2 (140, 148)

WDFKKIEK

PF16739 // ENSGT00510000046789_1_Domain_2 (148, 240)

LEEYRLLLKRLQPEFKTRIIPTDILSDLSECLI
NQECEEILQIC---STKGMMAGAEKLVECLLRSDKENWPKTLKLALERERN-KFSELWT

ENSGT00510000046789_1_Linker_2_3 (240, 307)

V
ENGIKDVETEDLE---D-KMETSDIQIFYQEDPECQ-NLSENSCPPSEVSD---TNLYSP
FKPRNY

PF00270 // ENSGT00510000046789_1_Domain_3 (307, 481)

QLELALPAKKGKNTIICAPT-GCGKTQVSILICEHHLK-KFPQGQKGKVVFFAN
QIPLYEQQESMF------SKYFERLGYRVTGISGATAENVPVEQIVENNDIIILTPQILV
NNLKKGTIPSLSIFTLMIFDECHNTSKQHPYNMIMFNYLDQKLGGSSGPLPQVVGLTASV

ENSGT00510000046789_1_Linker_3_4 (481, 729)

GVGDAKDTDEALDYICKLCASLDASVIATVKDNLEELEQVVYKPQKFFRKVESRISDKFK
CIIAQLMRDTESLAKRICKDL-----ENFSQIQNREFGTQKYEQWIVTVQKACMVFQMPD
KDEESRICKALFLYTSHLRKYNDALIISEHARIKDALDYLKD-FFSNV------------
-----------RAAGFDEIEQD--LTQRFEEKLQELE-SVSRDPSNENPKLED---LRFI
LQEEYHLN

PF00271 // ENSGT00510000046789_1_Domain_4 (729, 836)

PETITILFVKTRALVDALKNWIEGNPKLSFLKPGILTGRGKTNQNTGMTLPA
QKCILDAFKVNGDHNILIATSVADEGIDIAQCNLVILYEYVGNVIKMIQTRGRGR

ENSGT00510000046789_1_Linker_4_5 (836, 914)

ARGSK
CFLLTSNAGVIEKEQINMYKEKMMNDSILRLQTWDEAVFREMILH---IQTHEKLIRDSQ
EK-PKPVPDKENK

PF11648 // ENSGT00510000046789_1_Domain_5 (914, 1030)

KLLCGKCKALVCYTADVRVIEECHYTVLGDAFKECFVSRPHPKPKKF
SNFEKRAKIFCARQNCSHDWGIHVKYKTFE-IPVIKIESFVVEDIATGVQTLYSKWKDFH
FEKTPFDPAEMSK--------------

------------------------------------------------------------
------------------------------------------------------------
---------YSGLYEAIENWDFQNLEKQALM----APPPNDFLNQIV--------FELIF
LQICICC

PF16739 // ENSGT00510000046789_1_Domain_2 (188, 231)

EQVC---TTKGPMAGAEKMAECLLRSDKGSWPKTLKLALEKDG

ENSGT00510000046789_1_Linker_2_3 (231, 329)

N-IFNDLWII
DEGMKDVESEELE---DNRMEHSDIQIFYQEDPEDQ-NLSQNSCPPSGTCF---LL----
------DSKVALPA--DQECVCNTQM-C

PF04851 // ENSGT00510000046789_1_Domain_3 (329, 478)

CGKTFVSLLICEHHLL-KFPQGRKGKVVFFAN
HVPVYEQQKTVF------SRYFERLGYSVTGISGATAEKVPVAETIENNDIIVLTPQILV
NNLKNGTIPSLSVFTLMIFDECHNTSKHHPYNMIITGXXXXXX--XXXXSLQVIGLT

ENSGT00510000046789_1_Linker_3_4 (478, 727)

ASV
GVGDAKNIEEAMAYICKLCASLDASVIATVKENLEELEQVVYKPQKSKWVPSDKPL----
-------------------EL-----HY--------------------------------
----SRLTP--PSSFSFKQKYNDTLIISEDAQMKDALNYLKD-FFSNV------------
-----------RTAAFDDIEQD--LTRRFEGEGCFQN-RKPLESCS---GNLE---LYLF
VNEEYH

PF00271 // ENSGT00510000046789_1_Domain_4 (727, 836)

LNPETRTILFVKTRALVDALKKWIEENSALNFLKPGILTGRGKTSNKTGMTLPA
QKCVLDTFRANGD-NILIATSVADEGIDIAQCNLVILYEYVGNVIRMIQTRGRGR

ENSGT00510000046789_1_Linker_4_5 (836, 914)

AKGSK
CYLLSSNADVIEKEHINIIKEKMMNDSISRLQTWDEVTFQKRIYH---IQNQEKFIRDSQ
PK-SKFVPDKENK

PF11648 // ENSGT00510000046789_1_Domain_5 (914, 1031)

RLLCAKCKVLACYTADIR---ESHYTVIGDAFKERFVSKPHPKPLSY
GXXXKKEKIFCARQNCGHDWGIHVRYKTFE-IPVIKIESFVVEDIVTGLQKQYPRWKAFP
FKKIEFDATEMSK--------------

-----------------------------------MSQEDKERLKLYSDYITGILRP---
---TYVID-------CMSTWFSTDVIEKIKAE-ESNGPTQAASFFIKHLLELEERGWYQG
FLDVLEATGYTGLCQALTMSDFHHIEALDHPKRLLKTIHSTVKNNITPSEFVNHFTDCLM
SREIEEIKQVRLEITNKGEIAGAEKFIDILLRSDKQEWPKVFTLALQDEGHLEILGLWSD
KERRSVAENVEEE-----TSAFS--NLQYSVIPEQE-NLDYSVG--------SVSQSIS

PF04851 // ENSGT00510000046789_1_Domain_3 (300, 482)

T
VKLRKYQEELAKPAFTGKNTMICAPT-GSGKTLVSLVICKHHLE-CMPNGKKGKVLFMAT
KVPVYEQQKDVF------CKYFEGSRYKVEGVSGETAENFPVGLVIENSDIIILTPQILV
NCLQSGTVPSISVFSMMIFDECHNTIGNHPYNVLMFSYLDLKLNMPGVALPQIIGLTASV
G

ENSGT00510000046789_1_Linker_3_4 (482, 755)

TGKAKSLPEAIHYITRLCASLNIEVISTVKEHKEELAETVFKPTKSISIAPQRENDSFT
AIMSEIMSETEKMAKDFYPEL-----YSMSNIQNRSYGTQKYEQWIVDTQKKCCVLQMDD
KNKEMRICSSLFTYTEHLRKYNDSIMINDDARTKDALDFLEN-FFNNM------------
-----------KNGSFNEIEQK--LYNMFQDKLPQLL-DISK--NNINPKLEE---LQFI
LDESYHENPETRSLLFVKTRSLVSALKTWIEENP

PF00271 // ENSGT00510000046789_1_Domain_4 (755, 837)

LLQFLKPEILIGRSKRNESLGMTLSS
QKGALEAFKNSAESKLLIATSVADEGIDIQACNLVLLYEYVGNVTKMIQVRGRGRAKDSK
CFLITSKGEEAIKEENNLLREKLMNEAVTVLQKEEPESFVNKILE---IQKEEKHIRDMK
KLFERPKATEGNRKLLCKKCKTYACNTDDIRVIKDSHHMIIDKTFKDRYITKKHPKPRTF
EGYKKMYKIFCKRPECHEDWGVSGTYQGFQDLPLIKIEQFVIENP-DGTQEYKDKWVDVH
FTMKKLSTEEFLS--------------

-----------------------------------

PF16739 // ENSGT00510000046789_1_Domain_0 (36, 140)

MTTEQRRSLLAFQDYIRKTLDP---
---TYILS-------YMAPWFREEEVQYIQAEKNNKGPMEAATLFLKFLLELQEEGWFRG
FLDALDHAGYSGLYEAIES

ENSGT00510000046789_1_Linker_0_2 (140, 148)

WDFKKIEK

PF16739 // ENSGT00510000046789_1_Domain_2 (148, 240)

LEEYRLLLKRLQPEFKTRIIPTDILSDLSECLI
NQECEEILQIC---STKGMMAGAEKLVECLLRSDKENWPKTLKLALERERN-KFSELWT

ENSGT00510000046789_1_Linker_2_3 (240, 307)

V
EKGIKDVETEDLE---D-KMETSDIQIFYQEDPECQ-NLSENSCLPSEVSD---TNLYSP
FKLRNY

PF00270 // ENSGT00510000046789_1_Domain_3 (307, 481)

QLELALPAKKGKNTIICAPT-GCGKTLVSVLICEHHLK-KFPPGQKGKVVFFAN
QIPVYEQQESVF------SKYFERLGYRVTGISGATAENVPVEQIVENNDIIILTPQILV
NNLKKGTIPSLSVFTLMIFDECHNTSKQHPYNMIMFNYLDQKLGGSSGPLPQVIGLTASV

ENSGT00510000046789_1_Linker_3_4 (481, 726)

GVGDAKDTDEALDYICKLCASLDASVIATVKDNLEELEQVVYKPQKFFRKVESRVSDKFK
CIIAQLMKDTESLAKRICKDL-----ESFSQIQNREFGTQKYEQWIVTVQKACMVFQMPD
KDEESRICKALFLYTSHLRKYNDALIISEHARVKDALDYLKD-FFSNV------------
-----------RAAGFDETEQD--LTQRFEEKLQELE-SVSRDPSNENPKLED---LCFI
LQEEY

PF00271 // ENSGT00510000046789_1_Domain_4 (726, 836)

HLNPETITILFVKTRALVDALKNWIEGNPKLRFLKPGILTGRGKTNQNTGMTLPA
QKCILEAFKVSGDHNILIATSVADEGIDIAQCNLVILYEYVGNVIKMIQTRGRGR

ENSGT00510000046789_1_Linker_4_5 (836, 914)

ARGSK
CFLLTSNAGVIEKEQINMYKEKMMNDCILHLQTWDEAVFREKILH---IQTHEKLIRDSQ
EK-PKPVPDKENK

PF11648 // ENSGT00510000046789_1_Domain_5 (914, 1030)

KLLCGKCKALVCYTADIRVIEECHYTVLGDAFKECFVRRPHPKPKKF
SNFDKREKIFCARQNCSHDWGIHMKYKTFE-IPVIKIESFVVEDIATGVQTLYSKWKDFH
FEKIPFDPAEMAK--------------

-----------------------------------

PF16739 // ENSGT00510000046789_1_Domain_0 (36, 140)

MTTEQRRNLQAFGDYVRKILDP---
---TYILS-------YMTSWFREDEVQCIQAERNNKGPTEAATLFLKYLLELQEEGWFRG
FLDALAHAGYSGLYEAIES

ENSGT00510000046789_1_Linker_0_2 (140, 148)

WDFQKIEK

PF16739 // ENSGT00510000046789_1_Domain_2 (148, 233)

LEEYRLLLKRLQPEFKTRINPEDILPEISECLI
KQECEEIVQVC---SNKGTMAGAEKMVECLLRSDKENWPKTLTFALEKEES-

ENSGT00510000046789_1_Linker_2_3 (233, 314)

RFSELWIV
GKDIKDAEMKDLE---DERLETSEVQIFYQEDPEYQ-NLSQNSCLPSEESH---TSWHSP
FKPRNYQLELALP

PF04851 // ENSGT00510000046789_1_Domain_3 (314, 478)

AKEGKNTIICAPT-GCGKTFVSLLICEHHFN-NFPQGQKGKVVFFAN
QIPVYEQQKSVF------SKYFERLGYKVTGISGATTENIPVKQMVENNDIIILTPQILV
NNLKNGTIPSLSIFTLMIFDECHNTSKQHPYNMIMFHYLDQKLGGSSGPLPQVIGLT

ENSGT00510000046789_1_Linker_3_4 (478, 725)

ASV
GVGDAKNTEEAIDYICKLCASLDASVIATVKDNLEELEQVVHKPQKFFRKVESRTTDKFK
CIMSQLMRAIENLAKSIYEDI-----ESLSQIKNREFGTQKYEQWIVTIQKECSVFKMPD
KDEESRICKALFLYTSHLRKYNDALIINEHARMKDALDYLKH-FFSNV------------
-----------RAAGFNEIEQD--LTRRFEEKLQELE-SISRDPSNENPKLED---LCFV
LQEE

PF00271 // ENSGT00510000046789_1_Domain_4 (725, 836)

YHFNQETKTILFVKTRALVDALKKWIEENSNLSFLKPGILTGHGKTNQNIRMTLPA
QKCILDSFRASGDNNILIATSVADEGIDIAQCNLVILYEYVGNVIKMIQTRGRGR

ENSGT00510000046789_1_Linker_4_5 (836, 914)

AKGSK
CFLLTSNNDVIEKEKINICKEKMMNDSILNLQKWDEAVFKEKILY---IQNQEKLLRDSQ
EK-AKPIPDKENK

PF11648 // ENSGT00510000046789_1_Domain_5 (914, 1031)

KLLCRKCKTLACFTADIRVVEESHYTVLGGAFKECFVTKPHPRPKTY
MNFEKRAKIFCARQDCCHDWGIFVKYKTFE-IPVIKIESFVVEDVATGIQMLYPKWKNFH
FEKIPFDAAEMSK--------------

-----------------------------------

PF16739 // ENSGT00510000046789_1_Domain_0 (36, 140)

MTAEQRRNLHAFGDYVRKTLDP---
---TFILS-------YMAPWFRDDEVQHIQAEKNNKGPTEAASLFLQFLLELQEEGWFRG
FLDALNQAGYCGLCEAIES

ENSGT00510000046789_1_Linker_0_2 (140, 148)

WDFQKIEK

PF16739 // ENSGT00510000046789_1_Domain_2 (148, 237)

LEEYRSLLRRLQPEFKTTINPKDILPEIAECLI
SQECEEILQIC---SSKGLMAGAEKMVECLLRSDKENWPKTLKLALEKEES-RFSE

ENSGT00510000046789_1_Linker_2_3 (237, 306)

LWMV
DKGAEDVKMKDLE---DDEMKTCDVQIFYKEEPENQ-NLSQNSCSSSEAPH-----TYSP
LKPRK

PF00270 // ENSGT00510000046789_1_Domain_3 (306, 480)

YQLELALPAQNGKNTIICAPT-GCGKTFVSLLICEHHLK-KFPRGRKGKVVFFAI
QLPVYEQQKSVF------SKHFERLGYKVAGISGATSDTVCVEQIVENNDIIILTPQILV
NCLTNGTIPSLSVFTLMIFDECHNTSKQHPYNVIMFNYLDRKLGGSSDSLPQVIGLTAS

ENSGT00510000046789_1_Linker_3_4 (480, 721)

V
GVGDAKNKAEATEYICKLCASLDTSVIATVRDNLEELEEVVYKPQKFFRKVELRTTDRFK
CIISQLMMEIESLAKSIFEELGTITLGGLFQIQNSNFGTQKYEQWIVKVQKECAVFQMPD
KDKESRICKALFSYMSHLRIYNDALIINEHARMKDALDYLKD-FFRNI------------
-----------RAAGFDEIEQD--LTQRFEEKLQELE-SISIDPSNENPKLRD---LCFI

PF00271 // ENSGT00510000046789_1_Domain_4 (721, 836)

LQEEYHLNPETRTILFVKTRALVDALKKWIKENPKLSFLKPSILTGRGKTNQNIGMTLPA
QKCVLDTFRTDKDNKILITTSVADEGIDIAQCNLVILYEYVGNVIKMIQTRGRGR

ENSGT00510000046789_1_Linker_4_5 (836, 914)

ARGSK
CFLLTANADLIDKEKMNMYKEEMMNGAILILQTWDEAVFKEKIHQ---IQIREKIIRDNQ
GK-PEPVPDKKTK

PF11648 // ENSGT00510000046789_1_Domain_5 (914, 1031)

KLLCKKCKAFACYTADIRMVENCHFTVVGDAFRERFVSKLHPKPKSF
GNIEKRAKIYCARPDCSHDWGIYVRYKAFE-MPFIKIESFVVEDIATGVQTVHAKWKDFN
FEKLSFDAAEMAGGAQDLGLQGMGNLE

-----------------------------------

PF16739 // ENSGT00510000046789_1_Domain_0 (36, 140)

MTTEQRRSLQAFQDYIRKTLDP---
---TYILS-------YMAPWFREEEVQYIQAEKNNKGPMEAATLFLKFLLELQEEGWFRG
FLDALDHAGYSGLYEAIES

ENSGT00510000046789_1_Linker_0_2 (140, 148)

WDFKKIEK

PF16739 // ENSGT00510000046789_1_Domain_2 (148, 238)

LEEYRLLLKRLQPEFKTRIIPTDIISDLSECLI
NQECEEILQIC---STKGMMAGAEKLVECLLRSDKENWPKTLKLALEKERN-KFSEL

ENSGT00510000046789_1_Linker_2_3 (238, 306)

WIV
EKGIKDVETEDLE---D-KMETSDIQIFYQEDPECQ-NLSENSCPPSEVSD---TNLYSP
FKPRN

PF00270 // ENSGT00510000046789_1_Domain_3 (306, 481)

YQLELALPAMKGKNTIICAPT-GCGKTFVSLLICEHHLK-KFPQGQKGKVVFFAN
QIPVYEQQKSVF------SKYFERHGYRVTGISGATAENVPVEQIVENNDIIILTPQILV
NNLKKGTIPSLSIFTLMIFDECHNTSKQHPYNMIMFNYLDQKLGGSSGPLPQVIGLTASV

ENSGT00510000046789_1_Linker_3_4 (481, 727)

GVGDAKNTDEALDYICKLCASLDASVIATVKHNLEELEQVVYKPQKFFRKVESRISDKFK
YIIAQLMRDTESLAKRICKDL-----ENLSQIQNREFGTQKYEQWIVTVQKACMVFQMPD
KDEESRICKALFLYTSHLRKYNDALIISEHARMKDALDYLKD-FFSNV------------
-----------RAAGFDEIEQD--LTQRFEEKLQELE-SVSRDPSNENPKLED---LCFI
LQEEYH

PF00271 // ENSGT00510000046789_1_Domain_4 (727, 836)

LNPETITILFVKTRALVDALKNWIEGNPKLSFLKPGILTGRGKTNQNTGMTLPA
QKCILDAFKASGDHNILIATSVADEGIDIAQCNLVILYEYVGNVIKMIQTRGRGR

ENSGT00510000046789_1_Linker_4_5 (836, 914)

ARGSK
CFLLTSNAGVIEKEQINMYKEKMMNDSILRLQTWDEAVFREKILH---IQTHEKFIRDSQ
EK-PKPVPDKENK

PF11648 // ENSGT00510000046789_1_Domain_5 (914, 1030)

KLLCRKCKALACYTADVRVIEECHYTVLGDAFKECFVSRPHPKPKQF
SSFEKRAKIFCARQNCSHDWGIHVKYKTFE-IPVIKIESFVVEDIATGVQTLYSKWKDFH
FEKIPFDPAEMSK--------------

-----------------------------------MT

PF16739 // ENSGT00510000046789_1_Domain_0 (38, 140)

VEQRSSLRAFRDYIRKTLDP---
---TYIMS-------YMAPWLREEEMQYIQAEKNNKGPVEAATLFLKILLELQEEGWFRG
FLDALDHAGYSGLYEAIES

ENSGT00510000046789_1_Linker_0_2 (140, 148)

WDFQKIEK

PF16739 // ENSGT00510000046789_1_Domain_2 (148, 238)

LEEYRLLLKRLQPEFKSRIIPTDILPDLSECLI
NQECEEIIQIC---STKGMMAGAEKLVECLLRSDKENWPKTLKLALEKDRN-KFSEL

ENSGT00510000046789_1_Linker_2_3 (238, 307)

WIV
EKGIKDVETEDLE---E-KLETSDIQIFYQEDPECQ-NLSENSCLPSEVSD---TNLYSP
FKPRSY

PF00270 // ENSGT00510000046789_1_Domain_3 (307, 481)

QLELALPAKKGKNTIICAPT-GCGKTLVALLICEHHLK-KFPQGQKGKVVFFAN
QIPVYEQQKSVF------SKYFERLGYRVTGISGATAENVPVKQIVENNDIIILTPQILV
NNLKNGTIPSLSIFTLMIFDECHNTSKQHPYNMIMFNYLDQKLGGSSGPLPQVIGLTASV

ENSGT00510000046789_1_Linker_3_4 (481, 726)

GVGDAKNTDEALDYICKLCASLDASVIATVQDNLKELEQVVYKPQKFFRKVESRISDKFK
CIIAQLMRETEGLAKRICKDL-----ENLSQIQNREFGTQKYEQWIVTVQKACMVFQMPD
KDEESRICKALFLYTSHLRKYNDALIISEHARMKDALHYLKD-FFSNV------------
-----------RAAGFDETEQD--LTQRFEEKLQELE-SISRDPSNENPKLED---LCFI
LREEY

PF00271 // ENSGT00510000046789_1_Domain_4 (726, 836)

HLNPETITILFVKTRALVDALKNWIEGNSKLSFLKPGILTGRSKTNQNTGMTLPA
QKCILDSFKAHGDHNILIATSVADEGIDIAQCNLVILYEYVGNVIKMIQTRGRGR

ENSGT00510000046789_1_Linker_4_5 (836, 914)

ARGSK
CFLLTSNAAVIEKENINMYKEKMMNDSILRLQTWDEEVFKEKILH---IQIHEKFIRDSQ
EK-PKPVPDKENK

PF11648 // ENSGT00510000046789_1_Domain_5 (914, 1031)

KLLCRKCKAFACYTADIRVIEESQFTVLGDAFKECFVSRPHPKPKQF
SNFYKRAKIFCARQDCSHDWGIHVKYKTFE-IPVIKIESFVVEDIATGVQTLYSKWKDFH
FEKIPFDAAEMSK--------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------VIGLTASV
GVGDAKNTEEAIAYICKLCASLDTLVIATVKENLEELEQVVYKPQKISRKVEPRTTNIFK
SIISQLMKETEYLAKNISEEL-----GYLFQIQDRVYGTQKYEQWIVAIHKECRVFQLPD
KEEESRICKAMYLYTSHLRKYNDALIISEDAQMKDALDYLKD-FFNNV------------
-----------RAAAFDEIEQD--LTRRFEEKLPELE-NVSMDPSNENPKLKD---LHLI
LQ

PF00271 // ENSGT00510000046789_1_Domain_4 (723, 836)

EEYHVNAETRTILFVKTRALVDALKKWIEESSALKFLKPGILTGRGKTSNKTGMTLPA
QKYVLDAFRANGD-NILIATSVADEGIDIAQCNLVILYEYVGNVIKMIQTRGRGR

ENSGT00510000046789_1_Linker_4_5 (836, 914)

AKGSK
CYLLSSNADVIEKENINLHKEKMMNDSISSLQTWDEVTFQKRIRH---IQDQEKFIRDSH
PK-PKVVPDKGNS

PF11648 // ENSGT00510000046789_1_Domain_5 (914, 1030)

RLLCGKCKVLACYTADIRVIEESHHTVIGDAFKECFVSKPHPKPRSY
GNFEKKDKIFCARQNCGHDWGIHGRYMTFE-IPVIKIESFVVEDIVTGLQKQYTKWKDFP
FEKIEFYATEMSK--------------

-----------------------------------

PF16739 // ENSGT00510000046789_1_Domain_0 (36, 140)

MTTEQRRSLQAFQDYIRKTLDP---
---TYILS-------YMAPWFREEEVQYIQAEKNNKGPMEAATLFLKFLLELQEEGWFRG
FLDALDHAGYSGLYEAIES

ENSGT00510000046789_1_Linker_0_2 (140, 148)

WDFKKIEK

PF16739 // ENSGT00510000046789_1_Domain_2 (148, 238)

LEEYRLLLKRLQPEFKTRIIPTDIISDLSECLI
NQECEEILQIC---STKGMMAGAEKLVECLLRSDKENWPKTLKLALEKERN-KFSEL

ENSGT00510000046789_1_Linker_2_3 (238, 306)

WIV
EKGIKDVETEDLE---D-KMETSDIQIFYQEDPECQ-NLSENSCPPSEVSD---TNLYSP
FKPRN

PF00270 // ENSGT00510000046789_1_Domain_3 (306, 481)

YQLELALPAMKGKNTIICAPT-GCGKTFVSLLICEHHLK-KFPQGQKGKVVFFAN
QIPVYEQQKSVF------SKYFERHGYRVTGISGATAENVPVEQIVENNDIIILTPQILV
NNLKKGTIPSLSIFTLMIFDECHNTSKQHPYNMIMFNYLDQKLGGSSGPLPQVIGLTASV

ENSGT00510000046789_1_Linker_3_4 (481, 727)

GVGDAKNTDEALDYICKLCASLDASVIATVKHNLEELEQVVYKPQKFFRKVESRISDKFK
YIIAQLMRDTESLAKRICKDL-----ENLSQIQNREFGTQKYEQWIVTVQKACMVFQMPD
KDEESRICKALFLYTSHLRKYNDALIISEHARMKDALDYLKD-FFSNV------------
-----------RAAGFDEIEQD--LTQRFEEKLQELE-SVSRDPSNENPKLED---LCFI
LQEEYH

PF00271 // ENSGT00510000046789_1_Domain_4 (727, 836)

LNPETITILFVKTRALVDALKNWIEGNPKLSFLKPGILTGRGKTNQNTGMTLPA
QKCILDAFKASGDHNILIATSVADEGIDIAQCNLVILYEYVGNVIKMIQTRGRGR

ENSGT00510000046789_1_Linker_4_5 (836, 914)

ARGSK
CFLLTSNAGVIEKEQINMYKEKMMNDSILRLQTWDEAVFREKILH---IQTHEKFIRDSQ
EK-PKPVPDKENK

PF11648 // ENSGT00510000046789_1_Domain_5 (914, 1030)

KLLCRKCKALACYTADVRVIEECHYTVLGDAFKECFVSRPHPKPKQF
SSFEKRAKIFCARQNCSHDWGIHVKYKTFE-IPVIKIESFVVEDIATGVQTLYSKWKDFH
FEKIPFDPAEMSK--------------

-----------------------------------

PF16739 // ENSGT00510000046789_1_Domain_0 (36, 140)

MTAEQRHNLRAYSDYVRKSLDP---
---THILS-------YMTAWLREDEVQYIQAEKNNKGPMEAASLFLKLLLELQVEGWFRG
FLDALNHAGYSGLYEAIER

ENSGT00510000046789_1_Linker_0_2 (140, 148)

WDFQNLEK

PF16739 // ENSGT00510000046789_1_Domain_2 (148, 231)

LEDHRSLLRRLEPEFKARIIPTEILPEIAECLI
TQDCEEIRQVC---ISRGPMAGAEKMAECLLRSDKENWPKILKLALEKDG

ENSGT00510000046789_1_Linker_2_3 (231, 313)

N-IFNELWII
EEGMKDFEIKDLE---DDKIEHSDIQIFYQEDPGDQ-NLSQNPCSPSEVSH---TNLYSP
LKPRSYQLELAL

PF04851 // ENSGT00510000046789_1_Domain_3 (313, 478)

PAKEGKNTIIYAPT-GCGKTFVSLLICEHHLQ-KFSQGRKGKVVFFAN
QVPVYEQQKTVF------SRYFERLGYRVTGISGATAENVPVAQTIESNDIIILTPQILL
NNLKNGTVPSLSIFTLMIFDECHNTSKHHPYNMIMFNYLEQKLGGSSDPLPQVIGLT

ENSGT00510000046789_1_Linker_3_4 (478, 722)

ASV
GVGDAKNTEEAIAYICKLCASLDASVIATVKENLEELEQVVYKPQKISRKVKPRTTNRFK
LIISQLMKETEHMAKIISEEL-----GYLFEIQDRVFGTQKYEQWIVEVHKACRVFQLPD
KEEESRICKAMYLYTSHLRKYNDTLIISEDAQMKAGLDYLKD-FFNNV------------
-----------RAAAFDEIEQD--LTRRFEEKLPELE-NVSMDPSNENPKLKD---LHLI
L

PF00271 // ENSGT00510000046789_1_Domain_4 (722, 836)

QEEYHVNPKTRTILFVKTRALVDALKKWIEENSALNFLKPGILTGRGRTSNKTGMTLPA
QKCVLDSFRANGD-NILIATSVADEGIDIAQCNLVILYEYVGNVIKMIQSRGRGR

ENSGT00510000046789_1_Linker_4_5 (836, 914)

AKGSK
CYLLSSNADVIEKENTNLYKEKMMNDSISILQTWDEATFQKRIHH---IQGQEKFIRDSQ
PK-PKPVPDKGNK

PF11648 // ENSGT00510000046789_1_Domain_5 (914, 1030)

RLLCGKCKVLACYTDDIRVIEESHHTVIGDAFKECFVSKPHPKPRSY
GNFEKKEKIFCASQNCGHDWGIHGKYKTFE-IPVIKIESFVVEDIVTGLQKQYTKWKDFP
YKKIEFHATEMSK--------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------P-DCVR-----------------------------
---TFHLCGSLFTSWLVIWNFCHFPGIEFTGISGATAENVPVEQIVENNDIIILTPQILV
NNLKKGTIPSLSIFTLVIFDECHNPTKQHPYNMIMFNYLDQKLGGSSGPLPQVIGLTALV
GVGDAKNTDEALDYICKLCASLDASVIATVKHNLEELEQVVYKPQKFFRKVESWIIDKFK
CSIAQLMRDTE-----ICKDL-----SEIN------LIFCKYEQWIVTVQKACMVFQMPD
KDEESRICKALFLYTSHLRKYNDALIISEHARMKDALDYLKD-FFSNV------------
-----------QAAGFDEIEQD--LTQRFEEKLQELE-SVSRDPSNENPKLED---LCFI
LQEEYHL

PF00271 // ENSGT00510000046789_1_Domain_4 (728, 836)

NPETITILFVKTRALVDALKNWIEGNPKLSFLKPGILTGCGKTNQNTGMTLLA
QKCILDAFKANGDHNILIATSVADEGIDIAQCNLVILYEYVGNVIKMIQTRGRGR

ENSGT00510000046789_1_Linker_4_5 (836, 914)

ARGSK
CFLLTSNAE------------KMMNDSILPV-------------------FREKVSLDSQ
EK-PKPVPDKENK

PF11648 // ENSGT00510000046789_1_Domain_5 (914, 1020)

KLLCRKCKALACYTADVRVIEECHYTVLGDAFKECLVSRPHPKPKQF
SNFEKR--------NCSHDWGIHVKYKTFE-IPVIKIESFVVEDIATGIQTLYSKWKDFR
EDTI-----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------METSDIQIFYQEDPECQ-NLSENSCLPSEVSD---TNLYSP
FKLRNY

PF00270 // ENSGT00510000046789_1_Domain_3 (307, 481)

QLELALPAKKGKNTIICAPT-GCGKTLVAVLICEHHLK-KFPPGQKGKVVFFAN
QIPVYEQQESVF------SKYFERLGYRVTGISGATAENVPVEQIVENNDIIILTPQILV
NNLKKGTIPSLSVFTLMIFDECHNTSKQHPYNMIMFNYLDQKLGGSSGPLPQVIGLTASV

ENSGT00510000046789_1_Linker_3_4 (481, 727)

GVGDAKDTDEALDYICKLCASLDASVIATVKDNLEELEQVVYKPQKFFRKVESRVSDKFK
CIIAQLMRDTESLAKRICKDL-----ESFSQIQNREFGTQKYEQWIVTVQKACMVFQMPD
KDEESRICKALFLYTSHLRKYNDALIISEHARVKDALDYLKD-FFSNV------------
-----------RAAGFDETEQD--LTQRFEEKLQELE-SVSRDPSNENPKLED---LCFI
LQEEYH

PF00271 // ENSGT00510000046789_1_Domain_4 (727, 836)

LNPETITILFVKTRALVDALKNWIEGNPKLHFLKPGILTGRGKTNQNTGMTLPA
QKCILEAFKVNGDHNILIATSVADEGIDIAQCNLVILYEYVGNVIKMIQTRGRGR

ENSGT00510000046789_1_Linker_4_5 (836, 914)

ARGSK
CFLLTSNAGVIEKEQINMYKEKMMNDCILHLQTWDEAVFREKILH---IQTHEKLIRDSQ
EK-PKPVPDKENK

PF11648 // ENSGT00510000046789_1_Domain_5 (914, 1030)

KLLCGKCKALVCYTADIRVIEECHYTVLGDAFKECFVRRPHPKPKKF
SNFDKREKIFCARQNCSHDWGIHMKYKTFE-IPVIKIESFVVEDIATGVQTLYSKWKDFH
FEKIPFDPAEMAK--------------

-----------------------------------

PF16739 // ENSGT00510000046789_1_Domain_0 (36, 140)

MTAEQRQNLQAFRDYIKKILDP---
---TYILS-------YMSSWLEDEEVQYIQAEKNNKGPMEAASLFLQYLLKLQSEGWFQA
FLDALYHAGYCGLCDAIES

ENSGT00510000046789_1_Linker_0_2 (140, 148)

WDFSKIEK

PF16739 // ENSGT00510000046789_1_Domain_2 (148, 238)

LEEHRLLLRRLEPGFKATVDPNDILPEISECLI
NQECEEIRQIC---DTKGRMAGAEKMAECLIRSDKENWPKVLKLALEKDNS-KFSEL

ENSGT00510000046789_1_Linker_2_3 (238, 313)

WIV
DKGFKRAESKADE---DDGAEASSIEIFIQEEPECQ-NLSQNPGPPSEASS---NNLHSP
LKPRNYQLELAL

PF04851 // ENSGT00510000046789_1_Domain_3 (313, 478)

PAKKGKNTIICAPT-GCGKTFVSLLICEHHLK-KFPCGQKGKVVFFAN
QIPVYEQQATVF------SRYFERLGYNIASISGATSDSVSVQHIIEDNDIIILTPQILV
NNLNNGAIPSLSVFTLMIFDECHNTSKNHPYNQIMFRYLDHKLGESRDPLPQVVGLT

ENSGT00510000046789_1_Linker_3_4 (478, 726)

ASV
GVGDAKTAQEAMQHICKLCAALDASMIATVRDNVAELEQVVYKPQKISRKVASRTSNTFK
CIISQLMKETEKLAKGVSEEL-----GKLFQIQNREFGTQKYEQWIVGVHKACSVFQMAD
KEEESRVCKALFLYTSHLRKYNDALIISEDAQMTDALNYLKA-FFHDV------------
-----------REAAFDETEQE--LTRRFEEKLEELE-KVSRDPSNENPKLRD---LYLV
LQEEY

PF00271 // ENSGT00510000046789_1_Domain_4 (726, 836)

HLKPETKTILFVKTRALVDALKKWIEENPALSFLKPGILTGRGRTNQATGMTLPA
QKCVLEAFRASRDNNILIATSVADEGIDIAECNLVILYEYVGNVIKMIQTRGRGR

ENSGT00510000046789_1_Linker_4_5 (836, 914)

ARDSK
CFLLTSSVDVIEKEKANMIKEKIMNESILRLQTWDEMKFEKTVHH---IQLNEKLLRDSQ
HK-PQPVPDKENK

PF11648 // ENSGT00510000046789_1_Domain_5 (914, 1030)

KLLCGKCKNFACYTADIRVVETSHYTVLGDTFKERFVCKPHPKPKIY
DNFEKKAKIFCAKQNCSHDWGIFVRYKTFE-IPVIKIESFVVEDIVSGVQNRHSKWKDFH
FERIQFDPAEMSV--------------

-----------------------------------

PF16739 // ENSGT00510000046789_1_Domain_0 (36, 140)

MTDEQRRNLHAFRDYVRRTLDP---
---THILS-------YMGTWLGEDEVQYIQAEKNNKGTMEAASLFLQCLLQLQTDGWFRA
FLDALYHAGYCGLYEAIES

ENSGT00510000046789_1_Linker_0_2 (140, 148)

WDFKKIEK

PF16739 // ENSGT00510000046789_1_Domain_2 (148, 238)

LEEHRLLLRRLQPEFKARIIPTDILPEISECLI
NQECEEIKQIC---CTKGMMAGAEKMVDCLLKSDKENWPKALKLALEKENS-KFSEL

ENSGT00510000046789_1_Linker_2_3 (238, 312)

WMA
DEGIRNIEAKAVE---DDGMEISNIQIFIQEEPESQ-NFSANSLLPSEVPF---NNSYSP
LKPRNYQVELA

PF04851 // ENSGT00510000046789_1_Domain_3 (312, 478)

LPAKKGKNTIICAPT-GCGKTFVSLLICEHHLK-QFSHGRQGKIVFFAN
HIPVYEQQANVF------SRYFERLGYRVAGISGANADSIPVQHTIENNDIIILTPQILV
NNLKNGTIPSVSVFTLMVFDECHNTNKHHPYNQIMFSYLDQKLGGSADPLPQVVGLT

ENSGT00510000046789_1_Linker_3_4 (478, 723)

ASV
GVGDAKTVEEAMFHICRLCAALDASVIATVRHNVEELEQVVYKPEKISRKVESRTTNTFK
SIISQLMKETEHLAKNVSAEL-----GMLFQIQNREFGTQKYEQWIVAVHKACMVFRMPD
KEEESRICKALFLYTSHLRKYNDALIISEDAQMKDALNYLKH-FFQDV------------
-----------RAAAFDETEQD--LTRRFEEKLEELE-KVSVDPSNENPKLKD---LYLI
LQ

PF00271 // ENSGT00510000046789_1_Domain_4 (723, 836)

EEYHLNPETKTILFVKTRALVDALKKWIEENSALSFLKPGILTGRGKTNQATGMTHPA
QKCALETFRASGDN-ILIATSVADEGIDIAQCNLVILYEYVGNVIKMIQTRGRGR

ENSGT00510000046789_1_Linker_4_5 (836, 914)

ARGSK
CFLLTSNADVIEKENVNVFKEKMMNESISRLQMWDEMKFAETVRC---IQTDEKLTRDSQ
HK-PQPVPDRENK

PF11648 // ENSGT00510000046789_1_Domain_5 (914, 1030)

KLLCGKCKALACYTADIRVVEKSHYTVLGNAFKERFVYKLHPKPKIY
DSFEKKAKIFCARQNCGHDWGIHVRYKAFE-IPVIKIESFVVEDIATGAQNRHSKWKDFH
FDRIQFDATDMSK--------------

-----------------------------------

PF16739 // ENSGT00510000046789_1_Domain_0 (36, 140)

MTAEQRHNLRAYSDYVRKSLDP---
---THILS-------YMTAWLREDEVQYIQAEKNNKGPMEAASLFLKLLLELQVEGWFRG
FLDALNHAGYSGLYEAIER

ENSGT00510000046789_1_Linker_0_2 (140, 148)

WDFQNLEK

PF16739 // ENSGT00510000046789_1_Domain_2 (148, 231)

LEDHRSLLRRLEPEFKARIIPTEILPEIAECLI
TQDCEEIRQVC---ISRGPMAGAEKMAECLLRSDKENWPKILKLALEKDG

ENSGT00510000046789_1_Linker_2_3 (231, 313)

N-IFNELWII
EEGMKDFEIKDLE---DDKIEHSDIQIFYQEDPGDQ-NLSQNPCSPSEVSH---TNLYSP
LKPRSYQLELAL

PF04851 // ENSGT00510000046789_1_Domain_3 (313, 478)

PAKEGKNTIIYAPT-GCGKTFVSLLICEHHLQ-KFSQGRKGKVVFFAN
QVPVYEQQKTVF------SRYFERLGYRVTGISGATAENVPVAQTIESNDIIILTPQILL
NNLKNGTVPSLSIFTLMIFDECHNTSKHHPYNMIMFNYLEQKLGGSSDPLPQVIGLT

ENSGT00510000046789_1_Linker_3_4 (478, 722)

ASV
GVGDAKNTEEAIAYICKLCASLDASVIATVKENLEELEQVVYKPQKISRKVKPRTTNRFK
LIISQLMKETEHMAKIISEEL-----GYLFEIQDRVFGTQKYEQWIVEVHKACRVFQLPD
KEEESRICKAMYLYTSHLRKYNDTLIISEDAQMKAGLDYLKD-FFNNV------------
-----------RAAAFDEIEQD--LTRRFEEKLPELE-NVSMDPSNENPKLKD---LHLI
L

PF00271 // ENSGT00510000046789_1_Domain_4 (722, 836)

QEEYHVNPKTRTILFVKTRALVDALKKWIEENSALNFLKPGILTGRGRTSNKTGMTLPA
QKCVLDSFRANGD-NILIATSVADEGIDIAQCNLVILYEYVGNVIKMIQSRGRGR

ENSGT00510000046789_1_Linker_4_5 (836, 914)

AKGSK
CYLLSSNADVIEKENTNLYKEKMMNDSISILQTWDEATFQKRIHH---IQGQEKFIRDSQ
PK-PKPVPDKGNK

PF11648 // ENSGT00510000046789_1_Domain_5 (914, 1030)

RLLCGKCKVLACYTDDIRVIEESHHTVIGDAFKECFVSKPHPKPRSY
GNFEKKEKIFCASQNCGHDWGIHGKYKTFE-IPVIKIESFVVEDIVTGLQKQYTKWKDFP
YKKIEFHATEMSK--------------

-----------------------------------MTAEERRNLRTFGDYVRKTLDP---
---TYILG-------YMTPWLREDEMQYIQAEKNNKGTVEAASAFFNFLVELKEEGWFRG
FLDALQRAGYTGLYEAFESWDFQKIEKLEEHRLLLRRLQPEFKTSINPLDILPEISQCLI
NQECEEIRQVC---FNKGSMAGAEKMVECLVRSDKENWPKALKLALEKEEC-NFNELWIV
EKGAEDVEIKDLG---DGEMETSEVQIFYQEEPEYQ-NLSQSSCPPSEVSH---TNLYSP
LKP

PF00270 // ENSGT00510000046789_1_Domain_3 (304, 488)

RNYQLELALPAQNGKNTIICAPT-GCGKTFVSILICEHHLK-KFPQGQKGKIVFFAV
QIPVYEQQKSVF------SKYFERLGYTVAGISGATSEEVPVRQIVENNDIIVLTPQILV
NNLKDGIIPSLSVFTLMIFDECHNTSKHHPYNMIMFNYLDQKLGGSSDPLPQVIGLTASV
GVGDAKD

ENSGT00510000046789_1_Linker_3_4 (488, 755)

ITDAKMYICKLCAALDTSVIATVKDNLKELEEIVNKPQKFFRKVETRTTNKFK
CIISQLMVEIEKMAESVFEELGTLTLESLSHIQNREYGTQKYEQWIIAVQKACMVFQMPD
KNEESRICKALFLYTSHLRKYNDALMINEDARIKDALDFLKD-FFTNV------------
-----------RAAGFDEIEQD--LTQRFEEKLQELE-YVSMDPNNENPKLQD---LSFI
LQEEYHVNPDSRTILFVKTRALVDALKKWIEENP

PF00271 // ENSGT00510000046789_1_Domain_4 (755, 837)

KLSFLKPGILTGRGRTNQKIGMTLPA
QKCVLDTFRSNSDSKILIATSVADEGIDIAQCNLVILYEYVGNVIKMIQTRGRGRARGSK
CFLVTSKADVIEKEKINIYKEKLMNDSILSLQELDEAEFKKKIHRLLIIQNQEKFIRDNE
GK-AKPEPDKKNKKLLCRKCKAFACYTVDIRVVEESHYTVVGDAFRECFVSKPHPKPRTY
GSFEKKAKIHCARQGCSHDWGIYVKYRTFE-IPVIKIESFVVEDIATGAQSLYAKWKDFH
FEKIPFDAAEMSK--------------

-----------------------------------

PF16739 // ENSGT00510000046789_1_Domain_0 (36, 140)

MTTEQRRSLLAFQDYIRKTLDP---
---TYILS-------YMAPWFGEEEVQYIQAEKNNKGPMEAATLFLKFLLELQEEGWFRG
FLDALDHAGYSGLYEAIES

ENSGT00510000046789_1_Linker_0_2 (140, 148)

WDFKKIEK

PF16739 // ENSGT00510000046789_1_Domain_2 (148, 240)

LEEYRLLLKRLQPEFKTRIIPTDILSDLSECLI
NQECEEILQIC---STKGMMAGAEKLVECLLRSDKENWPKTLKLALERERN-KFSELWT

ENSGT00510000046789_1_Linker_2_3 (240, 307)

V
ENGIKDVETEDLE---D-KMETSDIQIFYQEDPECQ-NLSENSCPPSEVSD---TNLYGP
FKPRNY

PF00270 // ENSGT00510000046789_1_Domain_3 (307, 481)

QLELALPAKKGKNTIICAPT-GCGKTLVSILICEHHLK-KFPQGQKGKVVFFAN
QIPLYEQQESIF------SKYFERLGYRVTGISGATAENVPVEQIVENNDIIILTPQILV
NNLKKGTIPSLSVFTLMIFDECHNTSKQHPYNMIMFNYLDQKLGGSSGPLPQVVGLTASV

ENSGT00510000046789_1_Linker_3_4 (481, 729)

GVGDAKDTDEALDYICKLCASLDASVIATVKDNLEELEQVVYKPQKFFRKVESRISDKFK
CIIAQLMRDTESLAKRICKDL-----ENFSQIQNREFGTQKYEQWIVTVQKACMVFQMPD
KDEESRICKALFLYTSHLRKYNDALIISEHARMKDALDYLKD-FFSNV------------
-----------RAAGFDEIEQD--LTQRFEEKLQELE-SVSRDPSNENPKLED---LRFI
LQEEYHLN

PF00271 // ENSGT00510000046789_1_Domain_4 (729, 836)

PETITILFVKTRALVDALKNWIEGNPKLSFLKPGILTGRGKTNQNTGMTLPA
QKCILDAFKVNGDHNILIATSVADEGIDIAHCNLVILYEYVGNVIKMIQTRGRGR

ENSGT00510000046789_1_Linker_4_5 (836, 914)

ARGSK
CFLLTSNAGVIEKEQINMYKEKMMNDSILRLQTWDEAVFREMILH---IQTHEKLIRDSQ
EK-PKPVPDKENK

PF11648 // ENSGT00510000046789_1_Domain_5 (914, 1030)

KLLCGKCKALVCYTADIRVIEECHYTVLGDAFKECFVSRPHPKPKKF
SNFEKRAKIFCARQNCSHDWGIHVKYKTFE-IPVIKIESFVVEDIATGVQTLYSKWKDFH
FEKIPFDPAEMSK--------------

------------------------------------------------------------
------------------------NIQSIQAMKTNKGVTAAATLFLEYLLKFEETGWFRG
FLDALHGAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-----XXXXXXXXXXXXXXX
XXXXXXXXXXX---XXXTGIAGADKLVEYLLRSDKENWPKVLKLALEAEEY-EFSKLWIL
EEGTKDVEMENSQ---SEESGMSAVQICYKEESEQQ-NLSENPCSFSEIPE---KPLYSP
LKP

PF00270 // ENSGT00510000046789_1_Domain_3 (304, 488)

RSYQLELASPALEGKNTIICAPT-GCGKTFVALLICENHLT-NNPAGQKRKVVFLAT
HLPVYEQQKSVF------TKHFERLGYKVAGICGEIAEDAPVEHVVDNNDIIVLTPQILV
NNIKSGTIQSLSVFTLMIFDECHNTSKKHPYNVLMISYLDQKLGRSASPLPQIIGLTASV
GVGNAKD

ENSGT00510000046789_1_Linker_3_4 (488, 755)

KSDTIEHICQLCACLDASVISTVKKNVNDLEQVVYKPEKVFRKIEPQPVNKLK
FVISKLMEDIENLIEMTFKEFXXXXXXXXXXXXXXXXXXXXXXXX-----XXXXXXXXXX
XXXXXXXXXXXXXXXXXXXKYNDALIISEDARIQDAVRYLKE-FFRE-------------
------------AESFDETEKH--LTHQFEXXXXXXX-XXXXXXXXXXXXXXX---XXXX
XXXXXXXXXXXXXXXXXXXXXXXXALKKWMEENP

PF00271 // ENSGT00510000046789_1_Domain_4 (755, 833)

KLSYLKPVVLTGRGKRNQNSGMTLPS
QKGVLDSFRTSGENKILIATSVADEGIDIAQCNLVILYEYVGNVIKMIQTRXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---XXXXXXXXXXXX
XX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDTHHVVIGDAFKESFVTEPHPKPKCF
GLLEKTGKIFCAERSCHHDWGIFARYKTFD-VPVIKIDSFVVEDVATGLQTLYSKWKYCN
FIMIPFDAREMSN--------------

-----------------------------------MT

PF16739 // ENSGT00510000046789_1_Domain_0 (38, 140)

VEQRRSLRAFCDYIRKTLDP---
---TYILS-------YMAPWFREEEVQYIQAEKNNKGPMEAATLFLNILLELQEEGWFRG
FLDALAHAGYSGLYEAIES

ENSGT00510000046789_1_Linker_0_2 (140, 148)

WDFQKIEK

PF16739 // ENSGT00510000046789_1_Domain_2 (148, 239)

LEEHRLLLKRLQPEFKSRIIPTDILPDLSECLI
NQECEEIIQIC---STKGMMAGAEKLVECLLRSDKENWPKTLKLALEKERN-NFSELW

ENSGT00510000046789_1_Linker_2_3 (239, 329)

NV
EKGIKDVE----------------------------------------------------
---------------------------K

PF04851 // ENSGT00510000046789_1_Domain_3 (329, 478)

CGKTFVALLICEHHLK-KFPQGQKGKVVFFAN
QIPVYEQQKSVF------STYFERLGYRVTGISGATAEDVPVKQIVENNDIIILTPQILV
NNLKNGTIPSLLVFTLMIFDECHNTSKQHPYNMIMFNYLDQKLGGSSGPLPQVIGLT

ENSGT00510000046789_1_Linker_3_4 (478, 726)

ASV
GVGDAKNTDEALDYICKLCASLDASVIATVQDNLEELEQVVYKPQKFFRKVESRISNKFK
CIIAQLMRETESLAKRICKDL-----ENLSQIQNREFGTQKYEQWIVTVQKACMVFQMPD
KDEESRICKALFLYTSHLRKYNDALIISEHARVKDALHYLKD-FFSNV------------
-----------RAAGFDETEQD--LTQRFEEKLQELE-SVSRDPSNENPKLED---LCFI
LREEY

PF00271 // ENSGT00510000046789_1_Domain_4 (726, 836)

HLNPETITILFVKTRALVDALKNWIEGNSKLSFLKPGILTGRSKTNQNTGMTLPA
QKCILDSFKAHGDHNILIATSVADEGIDIAQCNLVILYEYVGNVIKMIQTRGRGR

ENSGT00510000046789_1_Linker_4_5 (836, 914)

ARGSK
CFLLTSNAAVIEKERINMYKEKMMNDSILRLQTWDEAVFKEKILH---IQIDEKFIRDSQ
EK-PKPVPDKENK

PF11648 // ENSGT00510000046789_1_Domain_5 (914, 1031)

KLLCRKCKAFACYTADIRVIEESHYTVLGDAFKECFVSRPHPQPKQF
SNFYKRAKIFCARQDCSHDWGIHVKYKTFE-IPVIKIESFVVEDIATGVQTLYSKWKDFH
FEKIPFDAAEMSR--------------

-----------------------------------MTAEQRRNLQAFGDYLRKMLDP---
---TCILS-------YMAPWLSEDKVQCIQAEKNNKGAMEAASLFLRCLLELQEDGWFQA
FLDALGHAGYSGLCEAIESWDFQKIDQLEDYRSLLKRLQPEFKNRINPRDILPDISGCLI
SQECEEILQXX---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXX
XXXXXXXXXXXXX---X-XXXXXXX-XXXXXXXXXX-XXXXXXXXXXXXXX---XXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXCGKTFISVLICEHHLG-NFPQGKKGKVVFFAN
KLPVYEQQKFVF------SKYFERRGYKVAGVCGATVESISVEQIVENNDIIILTPQILV
NSLNHRTIPSLSVFTLMIFDECHNTSKLHPYNMIMFNYLDQKLGGSSEPLPQILGLTASV
GVGNARNKTEAMEYILKVCASLDVSAIATVKDNLKELEEIVYKPQKFSRKVQSRTSDRFK
SIICQLMKETENLAKNVFEEF-----DKLSQYQSRDFGTQKYEQWIMKVQKMCAVFKMSD
KDEESRICKALFLYTSHLRKYNDALIIYEDARIKDALDYLTD-FFNEV------------
-----------RAAGFDEIEQD--LTRRFEEKLPELE-MVSMDPSNENPKLRD---LCFI
LLEEYHLKPDTRTILFVKTRALVNALKKWIEGNS

PF00271 // ENSGT00510000046789_1_Domain_4 (755, 837)

QLSFLKPGILTGRSKTSQTIGMTLPA
QKSALDTFRTNDNNKILIATSVADEGIDIAQCNLVILYEYVGNVIKMIQTRGRGRAKGSK
CYLLTSNDEVIEKEDMNICKEKMMNEAILYLQKLDDAVFKETXXXXXXXXXXXXXXXXXX
XX-X---XXXXXXXXXXXXXXXXXXXXXXXXXXXQCHYTVIGNSFKECFARKSHSKPENC
GSFEKKEKIFCV--KCNHDWGIHVKYKTFE-IPFIKIQGFVVEDILTGIQTPYTRWRDFD
FDKKTFDAAEMSN--------------

-----------------------------------

PF16739 // ENSGT00510000046789_1_Domain_0 (36, 140)

MTTEQRRSLLAFQDYIRKTLDP---
---TYILS-------YMAPWFREEEVQYIQAEKNNKGPMEAATLFLKFLLELQEEGWFRG
FLDALDHAGYSGLYEAIES

ENSGT00510000046789_1_Linker_0_2 (140, 148)

WDFKKIEK

PF16739 // ENSGT00510000046789_1_Domain_2 (148, 240)

LEEYRLLLKRLQPEFKTRIIPTDILSDLSECLI
NQECEEILQIC---STKGMMAGAEKLVECLLRSDKENWPKTLKLALERERN-KFSELWT

ENSGT00510000046789_1_Linker_2_3 (240, 307)

V
EKGIKDVETEDLE---D-KMETSDIQIFYQEDPECQ-NLSENSCLPSEVSD---TNLYSP
FKLRNY

PF00270 // ENSGT00510000046789_1_Domain_3 (307, 481)

QLELALPAKKGKNTIICAPT-GCGKTLVAVLICEHHLK-KFPPGQKGKVVFFAN
QIPVYEQQESVF------SKYFERLGYRVTGISGATAENVPVEQIVENNDIIILTPQILV
NNLKKGTIPSLSVFTLMIFDECHNTSKQHPYNMIMFNYLDQKLGGSSGPLPQVIGLTASV

ENSGT00510000046789_1_Linker_3_4 (481, 720)

GVGDAKDTDEALDYICKLCASLDASVIATVKDNLEELEQVVYKPQKFFRKVESRVSDKFK
CIIAQLMRDTESLAKRICKDL-----ESFSQIQNREFGTQKYEQWIVTVQKACMVFQMPD
KDEESRICKALFLYTSHLRKYNDALIISEHARVKDALDYLKD-FFSNV------------
-----------RAAGFDETEQD--LTQRFEEKLQELE-SVSRDPSNENPKLED---LCF

PF00271 // ENSGT00510000046789_1_Domain_4 (720, 836)

I
LQEEYHLNPETITILFVKTRALVDALKNWIEGNPKLHFLKPGILTGRGKTNQNTGMTLPA
QKCILEAFKVNGDHNILIATSVADEGIDIAQCNLVILYEYVGNVIKMIQTRGRGR

ENSGT00510000046789_1_Linker_4_5 (836, 914)

ARGSK
CFLLTSNAGVIEKEQINMYKEKMMNDCILHLQTWDEAVFREKILH---IQTHEKLIRDSQ
EK-PKPVPDKENK

PF11648 // ENSGT00510000046789_1_Domain_5 (914, 1030)

KLLCGKCKALVCYTADIRVIEECHYTVLGDAFKECFVRRPHPKPKKF
SNFDKREKIFCARQNCSHDWGIHMKYKTFE-IPVIKIESFVVEDIATGVQTLYSKWKDFH
FEKIPFDPAEMAK--------------

-----------------------------------MTPGERENLIAFRDYVIKILDP---
---TYIQC-------YVATWLSEEKLQFIQTEKNNKGATEAASIFFKYLLELQEEGWFRA
FLDALHQAGYSGLCEAFENWDFKKIDDLEDYRLLLRRLQPEFKTIVDPLDLLPHIDECLI
TQEYEEISQIC---SSKGRMAGAEKLVDCLIRSDKSNWPKMLQLALERENS-KFSELWIV
EKGAKKAEVEDLK---DDEVETFDVHFVYQEEAENQ-NLSQNPCPPSEAVEAEVSQTYC

PF04851 // ENSGT00510000046789_1_Domain_3 (300, 461)

P
LKPRNYQLELALPAKEEKNTIICAPT-GCGKTFVSLLICEHHLK-KFPQGQKGKVVFLAN
KLPVYEQQKSVF------SKYFERYGYRVAGICGSTTMTIVVEEVIKSNDIIILTPQILV
NALKNGTVPSLSIFTLMIFDECHNTNKLHPYNMIMFSYLD

ENSGT00510000046789_1_Linker_3_4 (461, 753)

QKLGKSSDPLPQXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXFRKVEARTNNRFK
CIIIQLMREIENLAKKVFKKF-----ENLSQLQTRDFGTQKYEQWIMIVQKVCSVLQMPD
KNEESRICKALFLYTSHLRKYNDALIISEDAQLMDALDYLKD-FYSEV------------
-----------RSAGFDEIEQD--LTRRFEEKLPELE-SLSVDPCNENPKLSD---LCFI
LQEEYHVNPDTRTLLFVKTRALVKALKKWIEG

PF00271 // ENSGT00510000046789_1_Domain_4 (753, 837)

NSQLNFLNPGILTGRGKTSENLGMTLPA
QKCVLDAFKTNGESKILIATSVAEEGIDIAQCNLVILYEYVGNVIKMIQTRGRGRAKGSR
AYLLTSSEEVIEKGN-DMYNVKMMNXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---XXX
XX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDNHHTVVGKAFKECFESKLHPKPGTY
GSFEKKEKIFCG--KCKLDWGIHVKYKTFE-IPVIKIQGFVVEDLETGQQRSYTKWKDFE
FDKKQFDDAD-----------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------METSGVQIFYQEDPECQ-NLSQNSCSPSDVSY---TDVNSR
FKPRNYQLELAL

PF04851 // ENSGT00510000046789_1_Domain_3 (313, 478)

PAKKGKNTIICAPT-GCGKTFVSLLICEHHLE-KFSQGQKGKVVFFAN
QIPVYEQQKSVF------SKYFERLGYRVTGISGATAENVPVEQIVENNDIIFLTPQILV
NNLKNGTIPSLSVFTLMIFDECHNTSKQHPYNMIMFNYLDQKLGGSVDPLPQVIGLT

ENSGT00510000046789_1_Linker_3_4 (478, 725)

ASV
GVGDAKNIDEAMEHICKLCAALDASVISTIKENLEELEQVVYKPQKFFRKVESRTTDPFK
FIISQLMRETESLAKNIHGHL-----GKLFQIQNREFGTQKYEQWIVQVQKACMVFRMPD
KNEESRICKALFLYTSHLRKYNDALIINEHARMKDALDYLKD-FFSNV------------
-----------RAAGFDEIEQD--LTWRFEEKLQELE-SVSMDPSKENPKLED---LCFV
LQEE

PF00271 // ENSGT00510000046789_1_Domain_4 (725, 836)

YHLNPGTRTILFVKTRALVDALKKWIEGNSKLSFLKPGILTGRCRTNQDIGMTLPA
QKCILDAFRTSGDNNILIATSVADEGIDIAQCNLVILYEYVGNVIKMIQTRGRGR

ENSGT00510000046789_1_Linker_4_5 (836, 914)

AKGSK
CFLLTSNADVIEKEQINMYKEKMMDESILSLQTWDEAEFKEKILH---IQIHEKFIRDSQ
GK-AKPVLDKENK

PF11648 // ENSGT00510000046789_1_Domain_5 (914, 1031)

KLLCRKCKTLACYTADVRVIEDTHYTVVGDAFKKCFVSKPHPKPKKF
CDFEKRAKIFCARQDCSHDWGIHVKYRTFE-IPVIKIESFVVEDVATGVQRLYSKWKDFH
FEKIPFDAAEMSR--------------

-----------------------------------MTAEERRNLQAFSDYVKRILDP---
---THILS-------YMNSWLGEDEVQYIQAEKNNKGPMEAASLFLKYLLQLKEEGWFRG
FLDALNNAGYSGLYEAIANWNFQKIEKLEEYRALLKRLQPAFKDRIDPTCILPEMSDCII
SQEYEEIMQVC---SNKGIMAGAEKMAECLLRSDKENWPKTLKLALDNDNN-SFSELWMV
EKDAKDVEAEDLE---EDDMGTSSIHIVYQEDPQLE-NLSQNSCTPAEVSR---AKLCSQ
LKPRNYQLELALPA

PF04851 // ENSGT00510000046789_1_Domain_3 (315, 478)

MKGKNTIICAPT-GCGKTFVSLLICEHHLK-TFPQGQKGKVVFFAN
HVPVYEQQKSVF------SEYFERLGYSVAGIAGATVENVPVQQIVENNDIIVLTPQILV
NNLKDGTIPSLSVFTLMIFDECHNTCKQHPYNKIMFYYLDQKLGGSSDPLPQVVGMT

ENSGT00510000046789_1_Linker_3_4 (478, 775)

ASV
GVGDAKNTDEAVEYICKLCASLDASVIATVKENLEELQEIVYTPQKISRRVESRTTNGFK
RIISQLMRETESLAKDVFEEL-----ENLSQIQNREFGTQKYEQWIVEVHKACRTFQLPD
KDEESRICKALYLYTSHLRKYNDALIISEHAQMKDALNYLNN-FFKDV------------
-----------RAAGFDETEQD--LTRRFEGKVQELE-TVSMDPSNENPKLKD---LYLI
LQEEYHVNPETKTILFVKTRALVDAIKKWIEENSKLSFLKPGILTGRGKTSQTT

PF00271 // ENSGT00510000046789_1_Domain_4 (775, 837)

GMTLPA
QKCVLDAFRSNGDHNILIATSVADEGIDIAQCNLVILYEYVGNVIKMIQTRGRGRA

ENSGT00510000046789_1_Linker_4_5 (837, 912)

KGSK
CLLLTSNADVIEKENINMYKEKMMNESILRLQTCDEAKFKKKLLC---IQTGEKIIRDNQ
QN-FKPKLDKQ

PF11648 // ENSGT00510000046789_1_Domain_5 (912, 1031)

NKKLLCAKCKALACYTSEIRMVKSDTTCMLSDSHCTLGICSPHPHPHNC
GDFDKIGKIFCARQDCSHDWGIRAKVNAFE-IPLIKIQSFVVEDTVTGKQMCPSKWKDFN
FEKIPFNPEELSE--------------

-----------------------------------

PF16739 // ENSGT00510000046789_1_Domain_0 (36, 140)

MTAEQRQNLQAFRNYVRKTLDP---
---TYILS-------YMGPWLQDEVVQFIQAEKNNKGPMEAASLFLQYLLQLQTEGWFRA
FLDALYSAGYCGLYEAIES

ENSGT00510000046789_1_Linker_0_3 (140, 176)

WDFQKLEKLEEHRLLLQRLQPEFKTRINPTDILPEL

PF04851 // ENSGT00510000046789_1_Domain_3 (176, 478)

SECLI
NQ----------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------GRKGKVVFFAN
QIPVYEQQATVF------SRYFERLGYSVAGVSGARADNVSMQDIIENKDIIILTPQILV
NSLNDGTIPSLSVFTLMIFDECHNTSKHHPYNQIMFRYLDHKLGGSPGPLPQVIGLT

ENSGT00510000046789_1_Linker_3_4 (478, 726)

ASV
GVGDAKTVEEAMLHICKLCAALDTSVIATVRDNVEELEQFVYKPQKFFRKVESRTTNTFK
SIISQLMKETEGLAKNVSEEL-----GKLFQIQNREFGTQRYEQWIVAVHKACMVFQMPD
KEKESSICRALFLYTSHLRKYNDALIISEHAQMKDALHYLKA-FFHDV------------
-----------KNAAFDETEQD--LTRRFEEKLEELE-EVSKDPSNENPKLRD---LYLI
LQEEY

PF00271 // ENSGT00510000046789_1_Domain_4 (726, 836)

HLKLETKTILFVKTRALVDALKKWIEENPALSFLKPGILTGRGRTNQATGMTLPA
QKCALEAFRASGDNNILIATSVADEGIDIAQCNLVILYEYVGNVIKMIQTRGRGR

ENSGT00510000046789_1_Linker_4_5 (836, 914)

ARDSK
CFLLTSNADVIEKEKVNMFKEKIMNESISMLQTWDEMKFEKTVQR---IQLDEKFIRDSQ
RK-PQPAPDKENK

PF11648 // ENSGT00510000046789_1_Domain_5 (914, 1030)

RLLCGKCKAFACYTADIRVVEKSHYTVLGNAFKERFVSKPHPKPKIY
DSFEKKAKIFCAIQKCCHDWGIHVKYKTFE-IPVIKIESFVVEDIASGVQRRHAKWKDFH
FERIQFDPAEMPI--------------

MGSQQPPGSPLSREEGEAPPPAPAPEGRRRSRRVRLRGSCRHRPSFLGRRELGTSAPAGT
ASVSEIMASAAKEFKMDNFSPKADEVQHIQAEKNNKGTMEAASLFLKFLLERQEEGWFRG
FLDALGHAGYSGLYEAIETWDFQKIESLEEYRSLLKRLQPEFKTTVNPKDILPEISQCLI
SQECEEIIQVC---SNKGLMAGAEKMVECLLRSDKENWPKTLKLALEMEES-KFSELWIV
DKDAKNVEPKVLE---DDEMETSDIQIFYKEESECQ-NLSQSSSPPSAASP-----TCRP
LKPRNYQLELTLPA

PF04851 // ENSGT00510000046789_1_Domain_3 (315, 468)

KEGKNTLICAPT-GCGKTLVSLLICEHHLK-KFPQERKGKVVFFAI
QLPLYEQQKSIF------SDYFEKLGYKVAGISGVTAETVSVEQIVENNDIIILTPQILV
NSLRNGTLPSLSVFTLMIFDECHNTGKNHPYNMIMFNYIDQKLGGSS

ENSGT00510000046789_1_Linker_3_4 (468, 775)

DPLPQVIGLTASV
GTGDAKNTKEAMEYICKLCASLDTAVIATVKDNLEELEEVAYKPQKFFRKVESRTTDRFK
CIISQLMRETESLAKSIFDELGTVTLENVSQIQNRSFGTQKYEQWIVSVQKACMVVQLPD
KDEESRICKALYLYTSHLRKYNDALMINEHARMKDALDYLKD-FFADV------------
-----------RSAGFDETEQD--LTRRFEEKLKELE-SVSMDLSNENPKLKD---LSFI
LQEEYHLNPESRTILFVKTRALVDALKKWIEENSELSFLNPGILTGRGKTNQNT

PF00271 // ENSGT00510000046789_1_Domain_4 (775, 837)

GMTLPA
QKCALDAFRTDGDKKILIATSVADEGIDIAECNLVILYEYVGNVIRMIQTRGRGRA

ENSGT00510000046789_1_Linker_4_5 (837, 911)

KGSK
CFLLTSNADVIEKEKINIYKENMMNESILRLQTWNEAVFKEKILQ---IQMQEKFIRDSQ
AK-VEPVPDK

PF11648 // ENSGT00510000046789_1_Domain_5 (911, 986)

ENKKLLCRKCKGFACYTADIRVVEDCHYAVVGDAFRKCYVSKLHPKPKTY
GHFEKKAKIFCARENCCHDWGIHVNVDPSK-GT---------------------------
---------------------------

-----------------------------------

PF16739 // ENSGT00510000046789_1_Domain_0 (36, 140)

MTAEQRRSLGAFRDYIRKTLDP---
---TYILS-------YMAPWIREEEVQYIQAEKNNKGPMEAATLFLKILLELQEEGWFRG
FLDALDHAGYSGLYEAIES

ENSGT00510000046789_1_Linker_0_2 (140, 148)

WDFQKIEK

PF16739 // ENSGT00510000046789_1_Domain_2 (148, 238)

LEEYRLLLKRLQPEFKSRIIPIDILPDLSECLI
NQECEEITQIC---STKGMMAGAEKLVECLLRSDKENWPKTLKFALEKERN-KFSEL

ENSGT00510000046789_1_Linker_2_3 (238, 307)

WII
EKGIKDVETEDLE---E-KMETSDIQIFYQEDPECQ-NLSENSCLPSEVSD---TDLYSP
FKLRSY

PF00270 // ENSGT00510000046789_1_Domain_3 (307, 480)

QLELALPAKKGKNTIICAPT-GCGKTFVALLICEHHLK-KFPQGQKGKVVFFAN
QIPVYEQQKSVF------SKYFERLGYRVTGISGATADNAPVKQMVENNDIIILTPQILV
NNLKNGTIPSLSVFTLMIFDECHNTSKQHPYNMIMFNYLDQKLGGSSGPLPQVIGLTAS

ENSGT00510000046789_1_Linker_3_4 (480, 727)

V
GVGDAKSTDEALDYICKLCASLDASVIATVRDNLEELEQVVYKPQKFFRKVESRINDKFK
CIIAQLMRETESLAKRICKDL-----ENLSQIQNREFGTQKYEQWIVTVQKACMVFQMPD
KDEESRICKALFLYTSHLRKYNDALIINEDARMKDALHYLKD-FFSNV------------
-----------RAAGFDETEQD--LTQRFEEKLQELE-SVSRDPSNENPKLED---LCFI
LREEYH

PF00271 // ENSGT00510000046789_1_Domain_4 (727, 836)

LNPETITILFVKTRALVDALKNWIEGNPQLSFLKPGILTGRSKTNQNTGMTLPA
QKCILDSFKAHGDHNILIATSVADEGIDIAQCNLVILYEYVGNVIKMIQTRGRGR

ENSGT00510000046789_1_Linker_4_5 (836, 914)

ARGSK
CFLLTSSAAVIEKENINMYKETMMNDSILRLQTWDEAEFKEKILH---IQIHEKFIRDSQ
EK-TKPVPDKENK

PF11648 // ENSGT00510000046789_1_Domain_5 (914, 1031)

KLLCRKCKAFACYTADIRVIEESHYTVLGDAFKECFVSRPHPKPTQF
SNFHKRAKIFCARRDCSHDWGIHVKYKTFE-IPVIKMESFVVEDIATGVQTLYSKWKDFH
FEKIPFDAAEMSTISEPQPSASGNE--

-----------------------------------

PF16739 // ENSGT00510000046789_1_Domain_0 (36, 140)

MTTEQRRSLQAFQDYIRKTLDP---
---TYILS-------YMAPWFREEEVQYIQAEKNNKGPMEAATLFLKFLLELQEEGWFRG
FLDALDHAGYSGLYEAIES

ENSGT00510000046789_1_Linker_0_2 (140, 148)

WDFKKIEK

PF16739 // ENSGT00510000046789_1_Domain_2 (148, 238)

LEEYRLLLKRLQPEFKTRIIPTDIISDLSECLI
NQECEEILQIC---STKGMMAGAEKLVECLLRSDKENWPKTLKLALEKERN-KFSEL

ENSGT00510000046789_1_Linker_2_3 (238, 306)

WIV
EKGIKDVETEDLE---D-KMETSDIQIFYQEDPECQ-NLSENSCPPSEVSD---TNLYSP
FKPRN

PF00270 // ENSGT00510000046789_1_Domain_3 (306, 481)

YQLELALPAMKGKNTIICAPT-GCGKTFVSLLICEHHLK-KFPQGQKGKVVFFAN
QIPVYEQQKSVF------SKYFERHGYRVTGISGATAENVPVEQIVENNDIIILTPQILV
NNLKKGTIPSLSIFTLMIFDECHNTSKQHPYNMIMFNYLDQKLGGSSGPLPQVIGLTASV

ENSGT00510000046789_1_Linker_3_4 (481, 726)

GVGDAKNTDEALDYICKLCASLDASVIATVKHNLEELEQVVYKPQKFFRKVESRISDKFK
YIIAQLMRDTESLAKRICKDL-----ENLSQIQNREFGTQKYEQWIVTVQKACMVFQMPD
KDEESRICKALFLYTSHLRKYNDALIISEHARMKDALDYLKD-FFSNV------------
-----------RAAGFDEIEQD--LTQRFEEKLQELE-SVSRDPSNENPKLED---LCFI
LQEEY

PF00271 // ENSGT00510000046789_1_Domain_4 (726, 836)

HLNPETITILFVKTRALVDALKNWIEGNPKLSFLKPSILTGRGKTNQNTGMTLPA
QKCILDAFKASGDHNILIATSVADEGIDIAQCNLVILYEYVGNVIKMIQTRGRGR

ENSGT00510000046789_1_Linker_4_5 (836, 914)

ARGSK
CFLLTSNAGVIEKEQINMYKEKMMNDSILRLQTWDEAVFREKILH---IQTHEKFIRDSQ
EK-PKPVPDKENK

PF11648 // ENSGT00510000046789_1_Domain_5 (914, 1030)

KLLCRKCKALACYTADVRVIEECHYTVLGDAFKECFVSRPHPKPKQF
SSFEKRAKIFCARQNCSHDWGIHVKYKTFE-IPVIKIESFVVEDIATGVQTLYSKWKDFH
FEKIPFDPAEMSK--------------

-----------------------------------

PF16739 // ENSGT00510000046789_1_Domain_0 (36, 140)

MTAEQRQNLQAFREYVRKTLDP---
---TYILS-------YMGPWLQEDEVQYIQAEKNNKGPMEAASLFLQYLLQLRSDGWFRA
FLDALYHAGYCGLYEAIES

ENSGT00510000046789_1_Linker_0_2 (140, 148)

WDFQKIEK

PF16739 // ENSGT00510000046789_1_Domain_2 (148, 238)

LEEHRLLLRRLQPEFKARINPTDILSELSECLI
NQECEEIRQIC---FTKGMMAGAEKMVECLLRSDKENWPKVLKLALEKEDN-KFSEL

ENSGT00510000046789_1_Linker_2_3 (238, 314)

WIV
DEGLKRVESKAAE---DDGTEMSSIQIFIQEEPECQ-ILSQNPCPPSEASS---NNLNSP
LKPRNYQLELALP

PF04851 // ENSGT00510000046789_1_Domain_3 (314, 478)

AEKGKNTIICAPT-GCGKTFVSLLICEHHLK-RFPRGQKGKVVFFAN
QIPVYEQQATVF------SRYFERLGYNVAGISGATTDNVSVQPIIENNDIIILTPQILV
NNLNNGTIPSLSVFTLMIFDECHNTSKHHPYNQIMFRYLDHKLGESPDPLPQVIGLT

ENSGT00510000046789_1_Linker_3_4 (478, 722)

ASV
GVGDAKTVEEAILHICKLCAALDVSVIATVRDNVEELEQVVYKPQKIFRKVESRTVNTFK
SIISQLMKETEKLAKNVSEEL-----GKFFQIQNREFGTQKYEQWIVAVHKACMVFQMPD
KEEESRICRALFLYTSHLRKYNDALIISEDAQMKDALNYLKA-FFHDV------------
-----------REAAFDETEQD--LTRRFEEKLEDLE-KVSTDPSNENPKLRD---LYLI
L

PF00271 // ENSGT00510000046789_1_Domain_4 (722, 836)

QEEYHLKPETKTILFVKTRALVDALKKWIEENPGLGFLKPGILTGRGKTNQATGMTLPA
QKCALEAFRASGDNNILIATSVADEGIDIAQCNLVILYEYVGNVIKMIQTRGRGR

ENSGT00510000046789_1_Linker_4_5 (836, 914)

ARDSK
CFLLTSNADVIEKEKVNMFKERIMNESISRLQTWDETKFEKMVRH---IQLDEKFIRDSQ
HK-PPPVPDKENK

PF11648 // ENSGT00510000046789_1_Domain_5 (914, 1030)

KLLCGKCKTFACYTADIRVVEQSHYTVLGEAFKERFVSKPHPKPKTY
DSFEKKAKIFCAIQNCRHDWGIHVRYKTFE-IPVIKIESFVVEDIASGAQNRHSKWKDFH
FDRKQFDPAEMSI--------------

-----------------------------------

PF16739 // ENSGT00510000046789_1_Domain_0 (36, 140)

MTAEQRQNLQAFRDYIKKILDP---
---TYILS-------YMSSWLRDDEVQCIQAEKNNKGPIEAASLFLRYLLELQTEGWFRA
FLDALYHAGYCGLYEAIET

ENSGT00510000046789_1_Linker_0_2 (140, 148)

WDFQKLEK

PF16739 // ENSGT00510000046789_1_Domain_2 (148, 234)

LEEHRLLLRRLEPEFKATVSPTDILSEISECLI
NQECEEIRQIC---FTKGRMAGAEKMVQCLLRSDKENWPKVLQFALEKDNS-K

ENSGT00510000046789_1_Linker_2_3 (234, 314)

FSELWLV
DKGVRRVDCKAVE---DDGTEMASIQIFIQEEPECQ-NLSQNPGPPSEASP---NNSHSP
LKPRNYQLELALP

PF04851 // ENSGT00510000046789_1_Domain_3 (314, 478)

AKKGKNTVICAPT-GCGKTFVSLLICEHHLK-NFPHGQKGKVVFFAN
QIPVYEQQATVF------SRYFERFGYNVAGISGATADNVSVQHIIENNDIVILTPQILV
NSLNNGAIPSLSVFTLMIFDECHNTSKHHPYNQIMFRYLDHKLGGSPDPLPQVIGLTASV
GVGDAKTVEEAMLHICKLCAALDASVIATVRDNVEELEQVVYKPQKISRKVESRASNTFK
CIISQLMREAERLAKNVSEEL-----GKFFQIQNREFGTQKYEQWIVAVHKACTVFQMPD
KDEESRICKALFLYTSHLRKYNDALIISEDAQMKDALNYLKA-FFHDV------------
-----------REAAFDETEQD--LTRRFEGFEEMD------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------

-----------------------------------MTAEQRRNLHAFGDYVRKTLDP---
---THILS-------YMAPWFRDDMVQYVQAEKNNKGTMEAASLFLRYLLELQEEGWFRG
FLDALDQAGYSGLYEAIESWDFQKIEKLEEHRALLRRLQPVFKTRVNPKDILPDISECLI
DQECEEIIQVC---SNKGLMAGAEKMVECLLRSDKENWPKTLKLALEKEES-VFSELWTV
EQGAKGVETKDLG---DEEIETSEIQIFYKEEPEYQ-NLSQNSSPPSAAQH---LNLLAP
LKIRNY

PF00270 // ENSGT00510000046789_1_Domain_3 (307, 480)

QLELALPAKEGKNTIICAPT-GCGKTLVSLLICEHHLK-KFPQGRKGKVVFFAI
HLPLYEQQKSVF------SQYFERRGYKVAGISGATSENVVVDQIVENNDIIILTPQILV
NSLKDGTIPSLSVFTLMMFDECHNTSKHHPYNMIMFNYLDQKLGGSSDPLPQVVGLTAS

ENSGT00510000046789_1_Linker_3_4 (480, 775)

V
GVGDAKNRDEAMEHICKLCASLDASVISTVKDNLQELTEVVYKPEKNFRKVESRTTDGFK
CIISQLMRETESLAKSIFDEL-----ENLSRFQNRDFGTQKYEQWIIAVQKACIVFQLPD
KAEESRICKALYLYTSHLRKYNDALIISEHARMKDALDYLKD-FFNNV------------
-----------RAAGFDETEQD--LTRRFEEKLPELE-SVSMDPSNENPKLKD---LCFI
LQEEYHLNPETRTILFVKTRALVDALKKWIEENPKLSFLKPGILTGRGKTTNNT

PF00271 // ENSGT00510000046789_1_Domain_4 (775, 837)

GMTLPA
QKCALDAFRTNGDNKILIATSVADEGIDIAQCNLVILYEYVGNVIKMIQTRGRGRA

ENSGT00510000046789_1_Linker_4_5 (837, 912)

KGSK
CFLLTSNADVIEKEKMNMYKEKMMNDSILSLQAWDEAIFKEKVCQ---IQIHEKSIRDSQ
GK-AKPVLDKK

PF11648 // ENSGT00510000046789_1_Domain_5 (912, 1032)

NKKLLCRKCKAFACYTADIRVVEECHYTVVGNAFRECFVCRSHPKPKIF
GSFEKKAKIYCAREDCSHDWGICVKYKTFE-IPVIKIESFVVEDIATRVQTLYAKWRDFN
FEKIPFDAAEMSN--------------

-----------------------------------

PF16739 // ENSGT00510000046789_1_Domain_0 (36, 140)

MTAEQRQNLQAFRNYIKKILDP---
---TYILS-------YMSSWLEDEEVQYIQAEKNNKGPMEAASLFLQYLLKLQSEGWFQA
FLDALYHAGYCGLCEAIES

ENSGT00510000046789_1_Linker_0_2 (140, 148)

WDFQKIEK

PF16739 // ENSGT00510000046789_1_Domain_2 (148, 238)

LEEHRLLLRRLEPGFKATVDPNDILSDLSECLI
DQECEEIRQIR---DTKGRMAGAEKMAECLIRSDKENWPKVLQLALEKDNS-KFSEL

ENSGT00510000046789_1_Linker_2_3 (238, 308)

WIV
DKGFKRAESKADE---DDGAEASSIQIFIQEEPECQ-NLSQNPGLPSEASS---NNLHSP
LKARNYQ

PF04851 // ENSGT00510000046789_1_Domain_3 (308, 478)

LELALPAKKGKNTIICAPT-GCGKTFVSLLICEHHLK-KFPRGQKGKVVFFAN
QIPVYEQQATVF------SRYFERLGYNIASISGATSDSVSVQHIIEDNDIIILTPQILV
NNLNNRAIPSLSVFTLMIFDECHNTSKNHPYNQIMFRYLDHKLGESRDPLPQVVGLT

ENSGT00510000046789_1_Linker_3_4 (478, 723)

ASV
GVGDAKTAEEAMQHICKLCAALDASEIATVRDNVAELEQVVYKPQKISRKVASRTSNTFK
CIISQLMKETEKLAKDVSEEL-----GKLFQIQNREFGTQKYEQWIVGVHKACSVFQMAD
KEEESRVCKALFLYTSHLRKYNDALIISEDAQMTDALNYLKA-FFRDV------------
-----------REAAFDETEQE--LTRRFEEKLEELE-KVSRDPSNENPKLRD---LYLV
LQ

PF00271 // ENSGT00510000046789_1_Domain_4 (723, 836)

EEYHLKPETKTILFVKTRALVDALKKWIEENPALSFLKPGILTGRGRTNQATGMTLPA
QKCVLEAFRASGDNNILIATSVADEGIDIAECNLVILYEYVGNVIKMIQTRGRGR

ENSGT00510000046789_1_Linker_4_5 (836, 914)

ARDSK
CFLLTSSADVIEKEKANMIKEKIMNESILRLQTWDEMKFGKTVHR---IQLNEKLLRDSQ
HK-PQPVPDKENK

PF11648 // ENSGT00510000046789_1_Domain_5 (914, 1030)

KLLCGKCKNFACYTADIRVVEMSHYTILGDAFKERFVCKPHPKPKIY
DNFEKKAKIFCAKQNCSHDWGIFVRYKTFE-IPVIKIESFVVEDIVSGVQNRHSKWKDFH
FERIQFDPAEMSV--------------

------------------------------------------------------------
--------------------------------------

PF16739 // ENSGT00510000046789_1_Domain_1 (99, 140)

MEAASLFLKFLLELQEEGWFRG
FLDALAHAGYSGLYEAIES

ENSGT00510000046789_1_Linker_1_2 (140, 148)

WDFQTIER

PF16739 // ENSGT00510000046789_1_Domain_2 (148, 239)

LEEYRSLLKRLQPEFKTTVNPKDILPEVSKCLI
SQECEEIMQVC---SNKGLMAGAEKMVECFLRSDKENWPKTLKLALDKEES-KFSELW

ENSGT00510000046789_1_Linker_2_3 (239, 307)

TV
DKGAKNIDVKVLE---DDEMETSDIQIFYKEESECQ-NLSQNSCPSSEVSH-----IYTP
VKPRNY

PF00270 // ENSGT00510000046789_1_Domain_3 (307, 480)

QLELALPAKEGKNTIICAPT-GCGKTFVSLLICEHHLK-NFPQGQKGKVVFFAV
QLPVYEQQKSVF------SNYFERLGYKVAGVSGATSENVSVKQIVENNDIIILTPQILV
NSLKNGTIPSLSVFTLMIFDECHNTGKHHPYNMIMFNYLDQKLGGSSDPLPQVIGLTAS

ENSGT00510000046789_1_Linker_3_4 (480, 720)

V
GIGDAKSTAEAVEYICRLCASLDTSVIATVKDNLEELEEIVYKPQKFFRKVESRTTDRFK
CIISQLMRETESLAKSIFDEIGTITLEGISQIRNREFGTQKYEQWIVTVQKACTVFQLPD
KDEESRICKALFLYTSHLRKYNDALIINEHARMKDALDYLKD-FFTNV------------
-----------RAAGFDEIEQD--LTRRFEEKLQKLE-SVSMDPSNENPKLKD---LCF

PF00271 // ENSGT00510000046789_1_Domain_4 (720, 836)

I
LQEEYHLNPESRTILFVKTRALVDALKKWIEENSELSFLKPGILTGRGKTNQNTGMTLPA
QKCALDAFRTNGDKKILIATSVADEGIDIAECNLVILYEYVGNVIKMIQTRGRGR

ENSGT00510000046789_1_Linker_4_5 (836, 914)

ARGSK
CFLLTSNAVVIEKEKINIYKEKMMNDSISMLQTWNEAVFKEKVLQ---IQIQEKVIRDSQ
GK-VEPVPDKENK

PF11648 // ENSGT00510000046789_1_Domain_5 (914, 1031)

KLLCRKCKAFACYTVDIRVVEECHYTVVGDAFRKCFVSKLHPKPKSF
GYFEKRAKIFCARPNCSHDWGIHVKYKIFE-IPVIKIESFVVEDIATGAQKLYAKWKDFH
FEKIPFDAKEMPK--------------

-----------------------------------MTAEERRDLHAVGDYVRKILDP---
---TYVLN-------FMAPWFKEEDMQFVQAEKNNKGTTEAASLFLKLLLELKEEGWFRG
FLDALNQAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXVC---SNKGMMAGAEKMIECLLRSDKENWPKTLKLALEKEEC-PFSELWTV
GKGEDDVEVKEPE---MDEMETSNV-LFYQEEPEYQ-NLSQNSCPPSEVSH---TNLGS

PF04851 // ENSGT00510000046789_1_Domain_3 (300, 482)

P
LKLRNYQLELALPAKEGKNTIICAPT-GCGKTFVALLICEHHLK-KFPQGQKGKVVFFAI
QLPVYEQQKSVF------SKHFERLGYKVAAISGATAEKVPVKAIVENNDIIILTPQILV
NNLKNGIIPSLSVFTLMIFDECHNTSKNHPYNMIMFNYLDQKLGGSSGPLPQIVGLTASV
G

ENSGT00510000046789_1_Linker_3_4 (482, 755)

IGDANDKCAAVEYICKLCASLDISVIATVKDNLEELEQIVYKPQKFFRKVEERTNNKFK
CIISQLMKETENLAESIIEELGTVTLENLSQIQNREFGTQRYEQWIIAVQKACAVFHMPD
KEKESRICKALFLYTSHLRKYNDALIISEHARIKDGLDHLKT-FFSNV------------
-----------RAAGFDETEQD--LTRRFEEKLQELE-CISMDPKNENPKLSD---LAFI
LQEEYHLNPETRTILFVKTRALVDALKKWIEENC

PF00271 // ENSGT00510000046789_1_Domain_4 (755, 833)

KLSSLKPGILTGHGKTSQKIGMTLPA
QKSVLDTFRTNGDNKILIATSVADEGIDIAQCNLVILYEYVGNVIKMIQTRXXXXXXXXX
XXXLTSNADVIAKEEINMYKEKLMNDSILSLQEWDEAVFQEKXXXXXXXXXXXXXXXX--
-X-XXXXXXXXXXXXXXXXXXXXXCGGIHIRVIEDSHYTVVGAAFKESFKRKPHPNPKSY
GSFEKREKIFCARQDCQHDWGIHVRYKTFE-IPIIKIEGFVVEDVATGHQMLYPRWKDFH
PEKIAFNAAEMFT--------------