Query Results 

-----------MNPREEKVKIITEEFIENDED----ADMERQK-------RNSKVRRQP-
-RKKQPPTA-VPKEMVSEESQLGNQP------E--------PVQEEPKTHLLSMTVRRGP
R----------SLPPIPSTS-RTGFAEFSMRGRMREKLQAARSKAESALLQEIPTPRPRR
LRSPS-KKELETE--FGTEPGKEVERTQQEI-DSQSYSRVKFRDSARKIKPKPQVPPGFP
SPEEAYNFFTFNFDPEPEESEEKP---KARHTVGTNQGEEEG--EEEEPPTRGRG---KE
MDEEELLTGDDAEDFLLGLDHMADDFVAVRPADYESIHDRLQMEREMLFIPSRQT----V
PTYKKLPENV-QPR-FLEDEGLYTG-VRPEVARTNQNIMENRLLMQDPERRWFGDDGRIL
ALPNPIKPFPSRRPVLTQEQSIKAELETLYKKAVKYVHS-SQHMIRSGDPP--GNFQLDI
-DISGLIF-THHPCF-SREHVLAAK----LAQLYDQYLA---------------------
----------RHQRNKAKFLTDKLQALRNAVQTGVDPEKPHSSLDTIQKTINEYKSEIRQ
TRKFRDAEQEKDRTLLKTIIKVWK-EMKSLREFQRFTNTPLKLVLRKEKVDQKTDE----
----------EAYEAEIQAEI-SELLEEHTEEYAQKM-EEYRTSLHQWKAWRKAQRAKKK
KR---KQAAEDHP-----DDEIEEPHPEEDLVKPTPPEPTNRAVIEQEVRERAAQNRRRP
W-

PF15625 // ENSGT00510000046611_0_Domain_0 (783, 967)

EPTLVPELSLAGSVTPSDQ-CPRAEVSRREDVKKRSVYLKVLFNNKEVSRTVSRPLGA
DFRVHFGQ---IFNLQIVNWPESLTLQVYE-TIGHSSPTLLA-EVFLPIPETTVVTGRAP
IE-EVEFSSNQHVTLDHEGVGSGVPFSFEADGSNQLILMT-----SGKVSHSVAWAIGEN
GIPLIP

ENSGT00510000046611_0_Linker_0_1 (967, 1210)

PLSQQNIGFRSALKRADAISSIGTSGLMDMKKLAKWAAESKLDPN-DPNNAPLM
QLISVATSGESYVPDFFRLEQLQQEFNFVSDQELNRSKRFRLLCLRSQEVPEFRNYKQVP
VYDREIMEKVFQDYEKRLRDRSVIETKEHIDTHRAIVAKYLQQVRESVINRFLIAKQYFL
LADMIVEEEVPNIS-----ILGL-SLFKLAEQKRPLRPRR-----KGRKKVTAQN-----
--LSDGDIK

PF00168 // ENSGT00510000046611_0_Domain_1 (1210, 1375)

LLVNIVRAYDIPVRKPAMSKFQQPSKSSRMFSEKRAASPSTHSPTHNADYP
LSQVLVRPFVEVSFQRTVCHTTTAEGPNPSWNEELELPF---RAPNGDYSTASLQSVKDI
VFINIFDEVLHDVLEDDRERGSG-IHTRIERHWLGCVKIPFSTIYFQARIDGTFKIDIPP
VLLGYSKERNMILERGFDSVRSLSEGSYITLFITIEPQLVPGESIRE------------K
FESQEDEKLLQATEKFQAECALKFPNRQCLTTVTDISGKTVFITRYLKPLNPPQELLNVY
PNNLQATAELVARYVSLIPFLPDTVSFGGICDLWSTSD---QFLDLLAGDEEEHAVLLCN
YFLSLGKKAWLLMGNAIPEGPTAYVLTWEQGHYLIWNPCSGHFYGQFDTFCPLKNVGCLI
GPDNIWFNIQRYDSPLRINFDVTKPKLWKSFFSRS-LPYPGLSSVQPEELIYQRSDKAAA
AELQD--RIEKILKEKIMDWRPRHLTRWNRYCTSTLRHFLPLLEKSQGEDVEDDHRAELL
KQLGDYRFSGFPLHMPYSEVKSLIDAVYSTGVHNIDVPNVEFALAVYIHPYPKNVLSVWI
YVASLTRNR

-----------MNPREEKVKIITEEFIENDED----ADMGRQN-------KNSKVRRQP-
-RKKQPPTA-VPKEMVSEKSHLGNPQ------E--------PVQEEPKTRLLSMTVRRGP
R----------SLPPIPSTS-RTGFAEFSMRGRMREKLQAARSKAESALLQEIPTPRPRR
LRSPS-KKELETE--FGTEPGKEVERTQQEV-DSQSYSRVKFHDSARKIKPKPQVPPGFP
SAEEAYNFFTFNFDPEPEGSEEKP---KARHRAGTNQEEEEG--EEEEPPAQGGG---KE
MDEEELLNGDDAEDFLLGLDHVADDFVAVRPADYESIHDRLQMEREMLFIPSRQT----V
PTYKKLPENV-QPR-FLEDEGLYTG-VRPEVARTNQNIMENRLLMQDPERRWFGDDGRIL
ALPNPIKPFPSRPPVLTQEQSIKAELETLYKKAVKYVHS-SQHVIRSGDPP--GNFQLDI
-DISGLIF-THHPCF-SREHVLAAK----LAQLYDQYLA---------------------
----------RHQRNKAKFLTDKLQALRNAVQTGLDPEKPHQSLDTIQKTINEYKSEIRQ
TRKFRDAEQEKDRTLLKTIIKVWK-EMKSLREFQRFTNTPLKLVLRKEKADQKADE----
----------EAYEAEIQAEI-SELLEEHTEEYAQKM-EEYRTSLQQWKAWRKVQRAKKK
KR---KQAAEEHP-----GDEIAEPYPEEDLVKPSPPEPTDRAVIEQEVRERAAQSRRRP
W-

PF15625 // ENSGT00510000046611_0_Domain_0 (783, 967)

EPTLVPELSLAGSVTPNDQ-CPRAEVSRREDVKKRSVYLKVLFNNKEVSRTVSRPLGA
DFRVHFGQ---IFNLQIVNWPESLTLQVYE-TVGHSSPTLLA-EVFLPIPETTVVTGRAP
TE-EVEFSSNQHVTLDHEGVGSGVPFSFEADGSNQLTLMT-----SGKVSHSVAWAIGEN
GIPLIP

ENSGT00510000046611_0_Linker_0_1 (967, 1210)

PLSQQNIGFRSALKKADAISSIGTSGLTDMKKLAKWAAESKLDPN-DPNNAPLM
QLISVATSGESYVPDFFRLEQLQQEFNFVSDQELNRSKRFRLLHLRSQEVPEFRNYKQVP
VYDREIMEKVFQDYEKRLRDRNVIETKEHIDTHRAIVAKYLQQVRESVINRFLIAKQYFL
LADMIVEEEVPNIS-----ILGL-SLFKLAEQKRPLRPRR-----KGRKKVTAQN-----
--LSDGDIK

PF00168 // ENSGT00510000046611_0_Domain_1 (1210, 1374)

LLVNIVRAYDIPVRKPAVSKFQQPSRSSRMFSEKHAASPSTYSPTHNADYP
LGQVLVRPFVEVSFQRTVCHTTTAEGPNPSWNEELELPF---RAPNGDYSTASLQSVKDV
VFINIFDEVLHDVLEDDRERGSG-IHTRIERHWLGCVKMPFSTIYFQARIDGTFKIDIPP
VLLGYSKERNMILERGFDSVRSLSEGSYITLFITIEPQLVPGESIRE------------K
FESQEDEKLLQATEKFQAECALKFPNRQCLTTVIDISGKTVFITRYLKPLNPPQELLNVY
PNNLQATAELVARYVSLIPFLPDTVSFGGICDLWSTSD---QFLDLLAGDEEEHAVLLCN
YFLSLGKKAWLLMGNAIPEGPTAYVLTWEQGRYLIWNPCSGHFYGQFDTFCPLKNVGCLI
GPDNIWFNIQRYESPLRINFDVTRPKLWKSFFSRS-LPYPGLSSVQPEELIYQRSDKAAA
AELQD--RIEKILKEKIMDWRPRHLTRWNRYCTSTLRHFLPLLEKSQGEDVEDDHRAELL
KQLGDYRFSGFPLHMPYSEVKPLIDAVYSTGVHNIDVPNVEFALAVYIHPYPKNVLSVWI
YVASLIRNR

------------------------------------------------------------
--------AGGPARLLSLFPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
X----------XLPPIPSAS-RTGFAEFSMRERMREKLQAARSKAESALLQEISTPRPRR
LHSPR-ERESETE--FGTELGKEERRSQQED-NSHHYSRVKFRDSVRKIKSKPQVPPGFP
SAEEAYHFFTFNFDPEPEEPEENP---QLKSRDGTNREGAAG--EGGPPEQQGDEAXXXX
XXXXXXXXXXXXXXXXXXX-----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----X
PTYKKLPENV-QPR-FLEDEGLYIG-ARPQVARATENIMENRLLVQELERGWFGDDGRIL
ALPNPIRPFPARPPVLPPGQDTTAELETLYKKAVKYVHS-GQHMVVSGDPP--GNFQVDI
-DISGLIF-THHPCF-SREHVLAAK----LAQLYDQYLA---------------------
----------RQQRNKAKFLTDKLHALRNAVQTGVNPEKPHQSLETTQKAIKEYKSEIRX
XXXXXXXXXXXXXXXXXTIIKVWK-EIKSLREFQRFTNTPLKLVLRKEKVDPKTEE----
----------EAFEAEIQAEI-SELLEEHTEEYEQKM-EEYRAAHQRWKAWKRAQRARKK
KK----HVAEEHP-----DEEIEEPLPEEEPVKPTAPEPTDRAALEQQVRERMARSRRRP
G-EPTLIPELSLVGSVTPNDQ-CPRVEVLRREDVRRRSVYLKVLFNNKEVSRTVSRQLAA
DFRVHFGQ---IFNLQIFNWPESLALQVYE-TVGHSSATLLA-EVFLPIPETTVVSGRAP
LE-EVEFSSDQHITLDHEGVGSGVPFSFEADGSNQLTLMT-----SGKVSHSVAWATGES
GIPLIPPLSQQNIGFRSALKRADAISSIGTSGLTDMKKLAKWATESKLDPN-DPNNAPLM
QLIS--------------------------------------------------------
------------DYEKRLRDRSIIETKDHIDTHRAMVAQYLQQVRESVINRFLIAKHHFL
PADLIVEEEVPN-----ISILGL-SLFKLAEQKRPLRPRR-----KGRKKVTAQN-----
--LSDGDIK

PF00168 // ENSGT00510000046611_0_Domain_1 (1210, 1334)

LLVNIIRAYDIPVRKPAPSKFQQPSRSSRSFMEKQAASPNTHSPSHSADYP
LGQVLVRPFVEVSFQRTVCHTTTAEGPNPSWNEELELPF---RAPNGDYSTASLQAVKDD
VFINIFDEVLYDVLEDDRERGSG-THTRIERHWLGCVKIPFSTIYFQA------------
-----------------------------------------------------------R
FDSQEDEKLLQATEKFQAECALKFANRQCLTTVTDISGKTVFITRYLRPLNPPEELLSAC
PNNPQATAELVARYVSLIPFLPDAVSFAGVCDLWTTSD---QFLDLLAGDEEEHAVLLCN
YFLSLGKKAWLVMGSAIPEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXVWFNIQHYDSPLRINFDVTKPKLWKPFFSRN-FPYPGLSSVQPEELIYQRTDKAAA
AELQD--RIEKILKEKIMDWRPRHLTRWNRYCTSTLRHFLPLLERSQGEDMEDDHRAELV
KQLGDYRFSGFPLHMAYSEMKPLVDAVYSTGVHSIDVPNVEFALAVYIHPYPKNVLSVWI
YVASLIRSR

-----------MNPKEEEVKIISEEFTGDDVD----ADAGRRK-------KNSKVQRKQ-
-RKKKPPST-TPEKMVSDKFQDSGQP------E--------MVEEEPETNLLSLTARRGP
R----------SLPPIPSAS-RTGFAEFSMRERMREKLQAARSKAESALLRDAPTPRPRR
LHSAS-ERETETE--FGTEASKEVGRTQQED-DSQSHSRFKLRDSAQKIKSKPQPPPGFP
TAEEAYNFFTFNFDPEPEEPEGKTQV---KGGDRAHPEDQEG--E--GACAQERT---KK
TEEEELLNGKDAEDLLLGLDPTAHDFVVVRAAEYESSHIQLQKEKEILFTPSRLT----V
PTYKKLPENV-QPR-FLEDEGLYIG-ARPEVARTNENIMENRLLIQEPGRKWFGDDGRIL
ALPSPIKPFPSRPSLSTQEQSTKAELETLYKKAVKYVHS-KQHMIGSGDPP--GNFQLDI
-DILGLIF-SHHPCF-SREHVLASK----LAQLYDQYLA---------------------
----------RQQRNKTKFLTDKLQALRKAVQTGLNPEKPHQSLDTTQKTINEYKSEIRQ
TRKLRDAEQEKDRTLLKTIIKVWK-EMKSLREFQRFTNTSLKLVLRKEKVDQKADE----
----------DEYEAEIQAEI-HELLEEDTEDYTKKL-EEYRALHQQWKAWRKTQRAKKK
KR---KQTAEEHPE---EEE-VEEPFPEEEIKKPIPPEPTDPAVIEQQVRERVAHSRRR

PF15625 // ENSGT00510000046611_0_Domain_0 (780, 967)

P
G-EPMLLPELSLAGNVTPNDQ-CPRVEVLRREDVRRRSVYLKVVFNSKEVSRTVSRPLGA
DFRVHFGQ---IFNLQIFNWPESLMLQVYE-TIGHSGTILLA-EVFLPIPETTLVTGRAP
IE-EVEFSSNQHVTLDHEGVGSGVPFSFEADGSNQLTLMT-----SGKVSHSVTWAVGEN
GIPLIP

ENSGT00510000046611_0_Linker_0_1 (967, 1210)

PLSQQNIGFRSALKSADAISSIGTSGLTDMKKLAKWAAESKLDPN-DPNNAPLM
QLISVATSGESYVPDFFRLEQLQQEFNFVSEEELNRSKRFRLLRLRSQEVPEFRNYKQIP
VYDREIMEKVFQDYEKRLRDRNIIETKDHLDAHRATVAKYLQQVRDSVVNRFLTAKHHFL
LTDLVVEEEVPNISSEGSGILGL-SLFKLAEQKRPLRPRR-----KGRKKVTAQN-----
--LCDGDIK

PF00168 // ENSGT00510000046611_0_Domain_1 (1210, 1375)

LLVNIIRAYDIPVRKPIVSKFQQPSRSSRTFSEKQTASPNTHSPVHNTDYP
LGQVLVRPFVEVSFQRTICHTTTAEGPNPSWNEELELPF---RAPNGDYSTASLQSVKDD
VYINIFDEVLYDILEDDRERGSG-IHTRIERHWLGCVKIPFSTIYFQARIDGTFKIDIPP
VLLGYSKERNIIMERTFDSARSLSEGSYITLFITIEPQLVPGEPIREKMSD----MLK-K
FDSQEDEKLLQATEKFQAECALRFPQRQCLTTVIDMSGKTVFITRFLKPLNPPQELLSVY
PNNPQATAELVARYVSLIPFLPDTVSFAGICDLWSTSD---QFLDLLAGDEEEHAVLLCN
YFLFLGKKAWLMMGNAIPEGPTAYVLTWEKNYYLIWNPCSGHCYGQFDTFCPLKSVGCLI
GPDNIWFNIQHHDSPLRINFDVTKPKLWKSFFSRS-LPYPGLSSVQPEELIYQRTDKAAA
AELQD--RIEKILKEKIMDWRPRHLTRWNRYCTSTLRHFLPLLERSQGEDIEDDHRAELL
KQLGDYRFSGFPLHMPYSEVKPLIEAVYSTGVHNIDVPNVEFALAVYIHPYPKNVLSVWI
YVASLVRNR

-----------MNPREEKVKIITEEFIENDED----ADMGGQK-------RNSKVRRQP-
-RKKQPPTA-VPKEMVSKESHFGNQP------E--------PVQEEPKTHLLSMTVRRGP
R----------SLPPIPSTS-RTGFAEFSMRGRMREKLQAARSKAESALLQEIPTPRPRR
LRSPS-KKELETE--FGTEPGKEVERTQQEI-DSQSYSRVKFHDSARKIKPKPQVPPGFP
SPEEAYNFFTFNFDHEPEESEEKP---KARHRAGTNQGEEEG--EEEEPTARGRG---KE
MDEEELLNGDDAEDFLLGLDHMADDFVAVRPADYESIHDRLQMETEMLFIPSRQT----V
PTYKKLPENV-QPR-FLEDEGLYTG-VRPEVARTNQNIMENRLLMQDPERRWFGDDGRIL
ALPNPIKPFPSRRPVLTQEQSIKAELETLYKKAVKYVHS-SQHMIRSGDPP--GNFQLDI
-DISGLIF-THHPCF-SREHVLAAK----LAQLHDQYLA---------------------
----------RHQRNKAKFLTDKLQALRNAVQTGIDPEKPHSSLDTIQKTINEYKSEIRQ
TRKFRDAEQEKDRTLLKTIIKVWK-EMKSLREFQRFTNTPLKLVLRKEKADQKADE----
----------EAYEAEIQAEI-SELLEEHTEEYAQKM-EEYRTSLHQWKAWRKAQRAKKK
KR---KQAAEDHP-----DDEIEEPHPEEDFVKPTPPEPTNRAVIEQEVRERAAQSRRRP
W-

PF15625 // ENSGT00510000046611_0_Domain_0 (783, 967)

EPTLVPELSLAGSVTPNDQ-CPRAEVSRREDVKKRSVYLKVLFNNKEVSRTVSRPLGA
DFRVHFGQ---IFNLQIVNWPQSLTLQVYE-TIGHSSPTLLA-EVFLPIPETTVVTGRAP
IE-EVEFSSNQHVTLDHEGVGSGVPFSFEADGSNQLILMT-----SGKVSHSVAWAIGEN
GIPLIP

ENSGT00510000046611_0_Linker_0_1 (967, 1210)

PLSQQNIGFRSALKRADAISSIGTSGLTDMKKLAKWAAESKLDPN-DPNNAPLM
QLISVATSGESYVPDFFRLEQLQQEFNFVSDQELNRSKRFRLLRLRSQKVPEFRNYKQVP
VYDREIMEKVFQDYEKRLRDRSVIETKEHIDTHRAIVAKYLQQVRESVINRFLIAKQYFL
LADMIVEEEVPNIS-----ILGL-SLFKLAEQKRPLRPRR-----KGRKKVTAQN-----
--LSDGDIK

PF00168 // ENSGT00510000046611_0_Domain_1 (1210, 1375)

LLVNIVRAYDIPVRKPAMSKFQQPSKSSRMFSEKRAASPSTHSPTHNAAYP
LGQVLVRPFVEVSFQRTVCHTTTAEGPNPSWNEELELPF---RAPNGDYSTASLQSVKDT
VFINIFDEVLHDVLEDDRERGSG-IHTRIERHWLGCVKIPFSTIYFQARIDGTFKIDIPP
VLLGYSKERNMILERGFDSVRSLSEGSYITLFITIEPQLVPGESIRE------------K
FESQEDEKLLQATEKFQAECALKFPNRQCLTTVIDISGKTVFITRYLKPLNPPQELLNVY
PNNLQATAELVARYVSLIPFLPDTVSFGGICDLWSTSD---QFLDLLAGDEEEHAVLLCN
YFLSLGKKAWLLMGNAIPEGPTAYVLTWEQGHYLIWNPCSGHFYGQFDTFCPLKNVGCLI
GPDNIWFNIQRYDSPLRINFDVTKPKLWKSFFSRS-LPYPGLSSVQPEELIYQRSDKAAA
AELQD--RIEKILKEKIMDWRPRHLTRWNRYCTSTLRHFLPLLEKSQGEDVEDDHRAELL
KQLGDYRFSGFPLHMPYSEVKPLIDAVYSTGVHNIDVPNVEFALAVYIHPYPKNVLSVWI
YVASLTCNR

------------------------------------------------------AGSTPC
KVNLIRPPTADLEEMVSQKPQEEDQQEP--------------TQEEPETRLLSMTARQGP
R----------SLPPIPAAS-RTGFAEFSMRERMREKLQAARL-------SQIPTTRPRR
LQSPG-DAELETE--FGMEPGKEVLRVQQED-DPQSYSRVKFRDSIQKSKYKPSVPPGFP
SAEEAYNFFTFNFEPEPEEPEEKP---KARSRDETKQEEKEE-REEEEPAVQEE---VNK
TXXXXXXXXXXXEDFLLGLDYTVGDFLAVRPAEYESIHTRVQVEKEILFVPSRWT----V
PTYKKLPENV-QPR-FLEDEGLYTG-ERPEVTCRNQNIVENRLLTQEPGRGWFGDDGRIL
ALPNPIKPFPAKSPVLKQGQDTHAELEIIYKKAVKYISS-SQHMIGTGDPS--GNFQLDI
-DISGLIF-THHPCF-SREHVLAAK----LAQLYDQYLA---------------------
----------RHQRNKAKFLTDKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQ
TRRLRDAEQEKDRMLLKTIIKVWK-EMKSLRDFQRFTNTPLKLVLRKEKIDQKADE----
----------EAYEAEIQAEI-SELLEEHLEDYEQKM-DEYRTTYQQWKAWKKAQXXXXX
XXXXXXXXXXXXXX---XXXXXXXXXXXXXXXXXX----XXXXXXXXXXXXXXXXX-XXX
X-XXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXX---XXXXXXXXXXXXXXXXXXX-XXXXXXXXXXX-XXXXXXXXXXXXXXXXX
XX-XXXXXXXXXXXXXXXXXXXXVPFSFEADGSNQLILMT-----SGKVSNSVAWAIGEN
GVPLIPPLSQQNVGVRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXDYEKRFRDRNVIETKDHIDTHRAVVAKYLQQXXXXXXXXXXXXXXXXX
-----XXXXXXXXXXXXXXILGL-SLFKLAEQKRPLRPRR-----KGRKKVTAQN-----
--LSDGDIK

PF00168 // ENSGT00510000046611_0_Domain_1 (1210, 1334)

LLVNIIRAYDIPVRKPAPSKFQQPSRSSRTFREKHAASPAMHSPADSADYP
FGQVLVRPFVEVSFQRTVCHTTTAEGPNPSWNEELELPF---RAPNGDYSTASLQSVKDD
VFINIFDEVLFDVLEDDRERGSG-IHTRIERHWLGSVKIPFSTIYFQA------------
-----------------------------------------------------------R
FDSQEDEKLLQATEKFQAECALKFPNRQCLMTVIDISGKTVFVTRYLRPLNPPQELLNIH
PKNAQATAELVARYVSLIPFLPDTVSFAGICDLWSTSD---QFLDLLAGDEEEHAVLLCN
YFLFLGKKAWLLMGNAIPEGPTAYVLTWEQNHYLIWNPCSGQFYGQFDTFCPLKSVGCLI
GPDNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---XXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXIEKILKEKLMDWRPRHLTRWNRYCTSTLRHFLPLLERSQGEEVADDHRAELL
KQLGDYRFSGFPLHMPYSEVKPLIEAVYSTGVHNIDVPNVEFALAVYVHPYPKNVLSVWI
YVASLIRNR

-----------MNPKEEKVKIITEEFSENNEV----AEVGRQK-------KTSKVARQK-
-RKKRLPTA-GPEEMVSENPHLGGQQEPEQ------------ED--SDTRPLSMMSRRGP
R----------SLPPIPSAS-RTGFAEFSMRERMREKLQAARSKAESTLLQEIPTTRPRR
LQSPS-KKELETE--FGTEPGEKVQRTKQED-DSQSYSRVKFRDSAQKIKSKPPVPPGFP
SAEEAYNFFTFNYDPEPEESEEKS---QTRNRDETNQEEEEG--EEEEPTVHGEHK-TVM
QDEEELLSAKDAEDFLLGLDHAAEDFVAVRPADYESVHVRLQREKELLFVPSRLT----V
PTYKKLPENV-QPR-FLEDEGLYIG-ARPEVPRTCQNIVENRLLTQDPGRKWFGDDGRIL
ALPNPTKGFPSRPPMLTQEQDIKAELETLYKKAIKYVHR-SQHMIGSGDTP--GNFQLDI
-DILGLIF-THHPCF-SREHVLAAK----LAQLYDQYLA---------------------
----------RHQRNKAKFLTDKLQALRIAVQTGLNPAKTHKSLDTTQKTINEYKSEIRQ
TRKLRDAEQEKDRTLLKTIIKVWK-EMKSLREFQRFTNTPLKLVLRKEKVDQKADE----
----------EAYEAEIQAEI-SELLEEHMEEHEQKM-EAYRAAYQQWKAWKKAQRAKKK
KKK---QAVEEHP-----DEEMEEPYPGEEPVKPVPPEPTDRALIEQQVRERAARSRR

PF15625 // ENSGT00510000046611_0_Domain_0 (779, 963)

RP
G-EPTLVPELSLAGSVTPNEQ-CPRVEVLRREDVKKRSVYLKVIFNDKEVSRTDSRPLGA
DFRVHFGQ---IFNLQIFNWPESLTLQVYE-TVGHSGTTLLA-EVFLPIPETTVVTGRAP
IE-EVEFSSNQHVTLDHEGVGSGVPFSFEADGSNQLILMT-----SGKVSNSVAWAIGEN
GIPLIPPLSQQNIGFRSALKRADAISSIGTSGLTDLKKLAKWAAESKLDPN-DPNNAPLM
QLISVATSGESYVPDFFRLEQLQQEFNFVSDEELNRSKRFRLLCLRSQEVPEFRNYKQIP
AYDREIMEKVFQDYEKRLQDRNVIETKDHIDTHRAIVAKYLQQVRESVINRFLIAKHHFL
LSDLIVEEE-----VPNISILGL-SLFKLAEQKRPLRPRR-----KGRKKVTAQN-----
--LSDGDIKVLVNIIRAYDIPVRKPTTSKFQQPSRSSRTFSEKRAASPTTHSPTHSSDYP
LGQVLVRPFVEVSFQRTICHTTTAEGPNPSWNEELELPF---RAPNGDYSTTSLQSVKDD
VFINIFDEVLYDVLEDDRERGSG-IHTRIERHWLGSVKIPFSTIYFQAKIDGTFKIDIPP
VLLGYSKERSMIMERGFDSVRSLSEGSYITLFITIEPQLVPGELVRE------------K
FDSQEDEKLLQATEKFQTECALKFPHRQCLTTVTDISGKTVFVTRYLKPLNPPQELLDAC
PNNPQATAELVARYVSLIPFLPDTVSFAGICDLWSTSD---QFLDLLAGDEEEHAVLLCN
YFLFLGKKAWLMMGNAIPEGPTAYVLTREQSHYLIWNPCSGHFYGQFDTFCPLKSVGCLI
GPDNIWFNTQRYDSPLRINFDVTKPKLWKSFFSRS-LPYPGLSSIQPEELIYQRTDKAAA
AELQD--RIEKILKEKIMDWRPRHLTRWNRYCTSALRHFLPVLERSRGEDVEDDHRAELL
KQLGDYRFSGFPLHMPYSELKPLIEAVYSTGVHNIDVPNVEFALAVYIHPYPKNVLSVWI
YVASLIRNR

-----------MTAKEEKVKIISEDFTGDGVD----TEAGRWK-------KNSKVRRQQ-
-RKKKPPAS-PPEEMVSDKFQDGGQQ------E--------VVEEEAETNLLSLTARRGP
R----------SLPPIPSAS-RTGFAEFSMRERMREKLQAARSKAESALLRDVPTPRPRR
LRSPSRERETETE--FGTEPSTEVQDIQKED-DTKIYSRIKFRDSVRKIKSKPQLPPGFP
SAEEAYNFFTFNFDPEPEESEEKSPV---KGGERAHQEDQGR--E-EGAQAQERA---KK
TEEEELLNGKDAEDFLLGLDPTAHDFVAVRAAEYKSAHIQLQKEKEILFTPSRLT----V
PTYKKLPENI-QPR-FLEDEGLYIG-ARPEVARTNENIMENRLLIQEPGSKWFGDDGRIL
ALPSPIKPFPSRPSLSTRDHSPKAELETLYKKAEKYVH--RQHMIGSGDPP--GNFQLDI
-DISGLIF-THHPCF-SREHVLASK----LAQLYDQYLA---------------------
----------RQQRNKTKFLTDKLQALRKAVQTSLNPEKPHPSLDTTQKTINEYKSEIRQ
TRKLRDAEQEKDRTLLKTIIKVWK-EMKSLREFQRFTNTPLKLVLRKEKVDPKLDE----
----------DAYEAEIQAEI-RELLEEHMEEYATKM-EEYRASHQQWKAWRKTQRAKKK
KK---KQTAEEHPE---E-EEDEEPFPEEEVKKPIPPEPADPAVIEQQVRERVAHSRRR

PF15625 // ENSGT00510000046611_0_Domain_0 (780, 967)

P
G-EPTLVPELSLAGNVTPNDQ-CPRVEVSRREDVRRRSVYLKVVFNGKEVSRTVSRPLGA
DFRVHFGQ---IFNLQIFNWPESLMLQVYE-TTGHSGTTLLA-EVFLPIPETTLVTGRAP
IE-EVEFSSNQHVTLDHEGVGSGVPFSFEADGSNQLTLMT-----SGKVSHSVAWAIGEN
GIPLIP

ENSGT00510000046611_0_Linker_0_1 (967, 1210)

PLSQQNIGFRSALKRADAISSIGTSGLTDMKKLAKWAAESKLDPN-DPNHAPLM
QLISVATSGESYVPDFFRLEQLQQEFNFVSEEELNRSKRFRLLHLRSQEVPEFRNYKQIP
AYDREIMEKVFQDYEKRLRDRNVIETKDHLDMHRAAVAKYLQQVREAVVNRFLTAKHHFL
LTDLVVEEEVPNISSEGSGILGL-SLFKLAEQKRPLRPRR-----KGRKKVTAQN-----
--LSDGDIK

PF00168 // ENSGT00510000046611_0_Domain_1 (1210, 1375)

LLVNIIRAYDIPVRKPVVSKFQQPSRSSRTFSEKQTASPSTHSPLHNADYP
LGQVLVRPFVEVSFQRTICHTTTAEGPNPSWNEELELPF---RAPNGDYSTASLQSVKDD
VYINIFDEVLYDILEDDRERGSG-IHTRIERHWLGCVKIPFSTIYFQARIDGTFKIDIPP
VLLGYSKERNIIMERAFDSARSLSEGSYITLFITIEPQLVPGEPIREKMSD----MLK-K
FDTQEDEKLLQATEKFQAECALKFPQRQCLTTVTDMTGKTVFITRYLKPLNPPQELLNVY
PNNPQATAELVARYVSLIPFLPDSVSFAGVCDLWSTSD---QFLDLLAGDEEEHAVLLCN
YFLFLGKKAWLVMGSAIPEGPTAYVLTWEKNYYLIWNPCSGHCYGQFDAFCPLKSVGCLI
GPDNIWFNIQHHDSPLRINFDVTKPKLWKSFFSRS-LPYPGLSSVQPGELIYQHTDKAAA
AELQD--RIEKILKEKIMDWRPRHLTRWNRYCTSTLRHFLPLLERSQGEDIEDDHRAELL
KQLGDYRFSGFPLHMPYSEVKPLVEAVYSTGVHNIDLPNVEFALAVYIHPYPKNVLSVWI
YVASLVRNR

-----------MNPREEKVKIITEEFIENDED----ADMGRQK-------RNSKVRRQP-
-RKKQPPTA-LPKEMVSEESHLGNQP------E--------PVQEEPNTHLLSMTVRRGP
R----------SLPPIPSTS-RTGFAEFSMRGRMREKLQAARSKAESALLQEIPTPRPRR
LRSPS-KKELETE--FGTEPGKEVESTQQEI-DSRSYSRVKFRDSARKIKPKPQVPPGFP
SPEEAYNFFTFSFDPEPEESEEKP---KARHRAGTNQEEEEG--EEEEPPARGRG---KE
MDEEELLNGDDAEDFLLGLDHMADDFVAVRPADYESIHDRLQMETEMLFIPSRQT----V
PTYKKLPENV-QPR-FLEDEGLYTG-VRPEVARTNQNIMENRLLMQDPERRWFGDDGRIL
ALPNPIKPFPSRRPVLTQEQSIKAELETLYKKAVKYVHS-SQHMISSGDHP--GNFQLDI
-DISGLIF-THHPCF-SREHVLAAK----LAQLYDQYLA---------------------
----------RHQRNKAKFLTDKLQALRNAVQTGVDPEKPHSSLDTIQKTINEYKSEIRQ
TRKFRDAEQEKDRTLLKTIIKVWK-EMKSLREFQRFTNTPLKLVLRKEKVDQKADE----
----------EAYEAEIQAEI-SELLEEHTEEYAQKM-EEYRTSLHQWKAWRKAQRAKKK
KR---KQAAEDHP-----DDEIEEPHPEEDLVKPTPPEPTDRAVIEHEVRERAAQSRRRP
W-

PF15625 // ENSGT00510000046611_0_Domain_0 (783, 967)

EPMLVPELSLAGSVTPSDQ-CPRAEVSRREDVKKRSVYLKVLFNNKEVSRTVSRPLGA
DFRVHFGQ---IFNLQIVNWPESLTLQVYE-TIGHSSPTLLA-EVFLPIPETTVVTGRAP
IE-EVEFSSNQHVTLDHEGVGSGVPFSFEADGSNQLILMT-----SGKVSHSVAWAIGEN
GIPLIP

ENSGT00510000046611_0_Linker_0_1 (967, 1210)

PLSQQNIGFRSALKRADAISSIGTSGLTDMKKLAKWAAESKLDPN-DPNNAPLM
QLISVATSGESYVPDFFRLEQLQQEFNFVSDQELNRSKRFRLLRLRSQEVPEFRNYKQVP
VYDREIMEKVFQDYEKRLQDRSVIETKEHIDTHRAIVAKYLQQVRESVINRFLIAKQYFL
LADMIVEEEVPNIS-----ILGL-SLFKLAEQKRPLRPRR-----KGRKKVTAQN-----
--LSDGDIK

PF00168 // ENSGT00510000046611_0_Domain_1 (1210, 1375)

LLVNIVRAYDIPVRKPAVSKFQQPSKSSRMFSEKRAASPSTHSPTHNADYP
LGQVLVRPFVEVSFQRTVCHTTTAEGPNPSWNEELELPF---KAPNGDYSTASLQSVKDI
VFINIFDEVLHDVLEDDRERGSG-IHTRIERHWLGCVKIPFSTIYFQARIDGTFKIDIPP
VLLGYNKERNMILERGFDSVRSLSEGSYITLFITIEPQLVPGESIRE------------K
FESQEDEKLLQATEKFQAECALKFPNRQCLTTVIDISGKTVFITRYLKPLNPPQELLNVY
PNNLQATAELVARYVSLIPFLPDTVSFGGICDLWSTSD---QFLDLLAGDEEEHAVLLCN
YFLSLGKKAWLLMGNAIPEGPTAYVLTWEQGHYLIWNPCSGHFYGQFDTFCPLKNVGCLI
GPDNIWFNIQRYDSPLRINFDVTKPKLWKSFFSRS-LPYPGLSSVQPEELIYQRSDKAAA
AELQD--RIEKILKEKIMDWRPRHLTRWNRYCTSTLRHFLPLLEKSQGEDVEDDHRAELL
KQLGDYRFSGFPLHMPYSEVKPLIDAVYSTGVHNIDVPNVEFALAVYIHPYPKNVLSVWI
YVASLIRNR

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------KKK---KKKKKKEEEEEKEKE--KEKSKEETEKRK-REN
EDEEELLSAKDDEDFLLGLDHTAEDFVAVRPSDYESVHVRLQMEKELLFVPSRLT----V
PTYKKLPENV-QPR-FLEDEGLYIG-ARPEVPRACQNIMENRLLTQEPGRKWFGDDGRIL
ALPNPTKGFPSRPPMLTREQDIKAELETLYKKAVKYVHR-SQHMIGSGDPP--GNFQLDI
-DISGLIF-THHPCF-SREHVLAAK----LAQLYDQYLA---------------------
----------RHQRNKAKFLTDKLQALRNAVQTGLNPAKPHKSLDTTQKAINEYKSEIRQ
TRKLRDAEQEKDRTLLKTIIKVWK-EMKSLREFQRFTNTPLKLVLRKEKVDQKADE----
----------EAFEAEIQAEI-SELLEEHMEEYDQKM-EGYRAAYQQWKAWKKAQRAKKK
KKK---QAVEEHP-----HGEVEQPCPGEEPVKPVPPEPTDRALVEQQVRERAARSRRRP
G-EPTLVPELSLAGSISPNEQ-CPRAEVLRREDVKRRSVYLKVIFNDKEVSRTDSRPLGA
DFRVHFGQ---IFNLQIFNWPESLTLQVYE-TVGHSGTTLLA-EVFLPVPETTVVTGRAP
IE-EVEFSSNQHVTLDHEGVGSGVPFSFEADGSNQLVLMT-----SGKVSNSVSWAIGEN
GIPLIPPLSEQNIGFRSALKRADAISSIGTSGLTDLKKLAKWAAESRLDPN-DPNNAPLM
QLISVATSGESYVPEFFRLEQLQQEFNFVSDEELNRSKRFRLLCLRSQEVPEFRNYKQIP
AYDREIMEKVFQDYEKRLRDRNVIETKDHIDTHRAIVAKYLQQVRKIILQ----SPHRFI
ISGIILNFSCTSLSSEGSGILGL-SLFKLAEQKRPLRPRR-----KGRKKVTAQT-----
--LSDGDIK

PF00168 // ENSGT00510000046611_0_Domain_1 (1210, 1334)

VLVNVIRAYDIPVRKPTASKFQQPARSSRTFSEKRAASPTTRSPTHSADYP
LGQVLVRPFVEVSFQRTMCHTTTAEGPNPSWNEELELPF---RAPNGDYSTASLQSVKDD
VFINIFDEVLYDVLEDDRERGRG-IHTRIERHWLGSVKIPFSTIYFQAKIDGTFKIDIPP
VLLGYSKERSLILERGFDAARSLSAGSYITLFITIEPQLVPGESVREKMSD----ML-KK
FDSQEDEKLLQATEKFQTECALKFPHRQCLTTVTDISGKTVFVTRYLKPLSPPQELLDAH
PNDPQATAELVARYVSLIPFLPDTVSFAGICDLWSTSD---QFLDLLAGDEEEHAVLLCN
YFLSLGKKAWLMMGSAIPEGPTAYVLTREQSHYLIWNPCTGHFYGQFDTFCPLKSVGCLI
GPDNIWFNTQRYDSPLRINFDVTKPKLWKSFFSRS-LPYPGLSSVQPEELIYQCTDKAAA
AELQD--RIEKILKEKIMDWRPRHLTRWNRYCTSALRHFLPVLERSRGEDAEDDHRAELL
KQLGDYRFSGFPLHMPYSELKPLTEAVYSTGVHNIDVPNVEFALAVYIHPYPKNVLSVWI
YVASLIRNR

-----------MNPREEKVSIITEESTANDED----AEVGRRE-------KSSKVQRQQ-
-RKKQPPRA-DSEEMVTGKA------QP--------------GQEEPEMHLLSMPARRGP
R----------SLPPIPSMS-RTGFAEFSMRERLREKLQAARSKAESALLQEIPTPRPRR
LRSPS-EKELETE--FGPEVRNNLKN-----------------------SHLKRAPPGFP
SAEEAYNFFTFSFDPEPEEPTVKA---RANNRDGTHQE-EE---GEEESPAG----GVNK
MDEEELLGSQDAKDFLLGLDPAPDEFVVVRPAEYEGTHTWLEKEKELLFFPSRRA----V
PTWKKLPENV-QPR-FLEDEGLYTG-ARPEVARAQQNVVENRLLRQEPGRKWFGDDGRIL
ALPSPIKPFSSRPPPLAQEPSAQAGLETHYKKAVKYVHR-TQHVVGSADPP--GSFQLDI
-DISGLIF-THHPCF-SREHVLAAK----LAQLYDQYLA---------------------
----------RHQRSKAKFLTDKVH------------------------TIKEYKSEIRE
TRKLRDAEQEKDRTLLKTIVKVWK-EMKSLREFQRFTNTPLKLVLRKEKVDQKADE----
----------EAYEAEIQAEI-SELMEEHTEEYEQRL-GEYRASYQQWKAWKKAQKAKKK
KKKQ----AEEHPE----GEAEEELYPGEEPVKPIPPELLDRAVLEQQARERAAHSRRR

PF15625 // ENSGT00510000046611_0_Domain_0 (780, 967)

P
G-EPVLLPELSLTGSVTPDDQ-CPRAEVLRREDVKRRSVYLKVLFNSKEVSRTVSRQLGA
DFCVHFGQ---IFNLQIFNWPESLTLQVYE-TVGHSSTTLLA-EVFLPIPETTTVTGRAP
VE-EVEFSSSQHVTLDHEGVGSGVPFSFEADGSNQLILMT-----SGRVSHSVAWATGDN
GTPLIP

ENSGT00510000046611_0_Linker_0_1 (967, 1252)

PPSQQSLGFRSALKRADAISSIGTSGLTDMKKLAKWAAESKLDPN-DPNNAPLM
QLISIATSGESYVPDFFRLEQLQQEFNFVTSEELNRSKRFRLLCLRSQEVPEFRNYKQIP
AYDREILEKVFQDYEKRLRDKSVIETKDHIDTHRAIVAKYLQQVRESVVNRFLIAKHHFL
LSDLVVEEEVPNMSSEGSGILGL-SLFKLAEQKRPLRPRR-----KGRKKVTAQN-----
--LSDGDIKLLVNICRAYDIPVRKPPASKSQQPARSSRTFSDRHAASPGAH

PF00168 // ENSGT00510000046611_0_Domain_1 (1252, 1304)

SPPHSPDTP
LSQVSVRPFVEVSFQRTICHTTTAEGPNPSWNEELEFPF---RAPNGDYSTASLQSVKDD
VFINIFDEVLHDILEDDRERGSG-IHTRNVYHV-----------TFSSQIDGTFKINTPP
VLLGYSKERNVLLERGLDSVRSLSEGSYLTLFITIEPQLVPGESVREKC------FFL-K
FDSQEDEKLLQATEKFQAECALKFPTRQCLTTVTDISGKTVFVTRYLKPLNPPEELLNAY
PNNPQATAELVARYVSLIPFLPDTVSFAGICDLWSTSD---QFLDLLAGDEEEHAVLLCD
YFLFLGKKAWLVMGNAIPEGPTAYVLTWEQNHYLIWNPCSGHFYAQFDTFCPLKSVSCLI
GPDNIWFNIQQYDSPLRINFDVTKPKLWKSFFSRS-LPYPGLSSVQPEELIYQRTDKAAA
AELQD--RIEKMLKEKIMDWRPRHLTRWNRHCTSTLRHFLPLLERSQGEDVEDEHRAELQ
KQLGDYRFSGFPLHMPYSEVKPLIEAVYSTGVHNTDVPNVEFALAVYIHPYPKNVLSVWI
YVASLIRNR

-----------MNPREEKVKIITEEFIENDED----ADMGRQN-------KNSKVRRQP-
-RKKQPPTA-VPKEMVSEKSHLGNPQ------E--------PVQEEPKTRLLSMTVRRGP
R----------SLPPIPSTS-RTGFAEFSMRGRMREKLQAARSKAESALLQEIPTPRPRR
LRSPS-KKELETE--FGTEPGKEVERTQQEI-DSQSYSRVKFHDSARKIKPKPQVPPGFP
SAEEAYNFFTFNFDPEPEGSEEKP---KARHRAGTNQEEEEE--EEEEPPAQGGG---KE
MDEEELLNGDDAEDFLLGLDHVADDFVAVRPADYESIHDRLQMEREMLFIPSRQT----V
PTYKKLPENV-QPR-FLEDEGLYTG-VRPEVARTNQNIMENRLLMQDPERRWFGDDGRIL
ALPNPIKPFPSRPPVLTQEQSIKAELETLYKKAVKYVHS-SQHVIRSGDPP--GNFQLDI
-DISGLIF-THHPCF-SREHVLAAK----LAQLYDQYLA---------------------
----------RHQRNKAKFLTDKLQALRNAVQTGLDPEKPHQSLDTIQKTINEYKSEIRQ
TRKFRDAEQEKDRTLLKTIIKVWK-EMKSLREFQRFTNTPLKLVLRKEKADQKADE----
----------EAYEAEIQAEI-SELLEEHKEEYAQKM-EEYRTSLQQWKAWRKAQRAKKK
KR---KQAAEEHP-----GDEIAEPYPEEDLVKPSPPEPTDRAVIEQEVRERAAQSRRRP
W-

PF15625 // ENSGT00510000046611_0_Domain_0 (783, 967)

EPTLVPELSLAGSVTPNDQ-CPRAEVSRREDVKKRSVYLKVLFNNKEVSRTVSRPLGA
DFRVHFGQ---IFNLQIVNWPESLTLQVYE-TIGHSSPTLLA-EVFLPIPETTVVTGRAP
TE-EVEFSSNQHVTLDHEGVGSGVPFSFEADGSNQLTLMT-----SGKVSHSVAWAIGEN
GIPLIP

ENSGT00510000046611_0_Linker_0_1 (967, 1210)

PLSQQNIGFRSALKKADAISSIGTSGLTDMKKLAKWAAESKLDPN-DPNNAPLM
QLISVATSGESYVPDFFRLEQLQQEFNFVSDQELNRSKRFRLLHLRSQEVPEFRNYKQVP
VYDREIMEKVFQDYEKRLRDRNVIETKEHIDTHRAIVAKYLQQVRESVINRFLIAKQYFL
LADMIVEEEVPNIS-----ILGL-SLFKLAEQKRPLRPRR-----KGRKKVTAQN-----
--LSDGDIK

PF00168 // ENSGT00510000046611_0_Domain_1 (1210, 1375)

LLVNIVRAYDIPVRKPAVSKFQQPSRSSRMFSEKHAASPSTYSPIHNADYP
LSQVLVRPFVEVSFQRTVCHTTTAEGPNPSWNEELELPF---RAPNGDYSTASLQSVKDV
VFINIFDEVLHDVLEDDRERGSG-IHTRIERHWLGCVKIPFSTIYFQARIDGTFKIDIPP
VLLGYSKERNMILEWGFDSVRSLSEGSYITLFITIEPQLVPGESIREKMSN----MLK-K
FESQEDEKLLQATEKFQAECALKFPNRQCLTTVIDISGKTVFITRYLKPLNPPQELLNVY
PNNLQATAELVARYVSLIPFLPDTVSFGGICDLWSTSD---QFLDLLAGDEEEHAVLLCN
YFLSLGKKAWLLMGNAIPEGPTAYVLTWEQGRYLIWNPCSGHFYGQFDTFCPLKNVGCLI
GPDNIWFNIQRYDSPLRINFDVTRPKLWKSFFSRS-LPYPGLSSVQPEELIYQRSDKAAA
AELQD--RIEKILKEKIMDWRPRHLTRWNRYCTSTLRHFLPLLEKSQGEDVEDDHRAELL
KQLGDYRFSGFPLHMPYSEVKPLIDAVYSTGVHNIDVPNVEFALAVYIHPYPKNVLSVWI
YVASLIRNR

------------------------------------------------------------
-----QLHTAGPKEMVSGKPHSGSQQEPAQ------------EDQDPDTHLLSMPTQRGP
R----------SLPPLPSAS-RTGFAEFSMRERMREKLKAARSKAESALLQEIPTPRPRR
LRSPS-EKELETE--FGVEPGRETQRTAQDD-DSQSYPRVKFRDCVRKIKSKPPLPPGFP
SAEEAYNFFTFTFDPEPEELEEKP---KAKHREGANQEEAEG--EEEGPPVQG----VNK
TDEEALLNGRDAEHFLLGLDHGAEDFVAVRPAYYESVHIRLQKEKELLFIPSRLT----V
PTYKKLPENV-QPR-FLEDEGLYIG-TRPEVPRATQNIMENRLLVQESDRRWFGDDGRIL
ALPNPIRPSPSRPPALTQEQNIHAELETLYKKAVRYVQK-TQHMIGSGEVP--ENFQLDI
-DISGLIF-THHPCF-SREHVLAAK----LAQLYDQYLA---------------------
----------RRQRNKAQFLTDKLQALRNAVQMGLDPAKSHKSVDITPKAINEYKSEIRQ
TRKLRDAEQETDRTLLKTIIKVWK-EMKSLREFQRFTNTPLKLVLRKEKVDQKADE----
----------EAYEAEIQAEI-SELLEEHSEAYEQKM-EEYRTEYQQWKAWRKAQRAKKK
KKK---QATEEHP-----DEEVEEPSPGEGPVKPIPPEPTQRAVLEQQVRERAARSRRRP
G-EPTLVPELSLAGSVTPNDQ-CPRAEVLRREDVKRRSVYLKVIFNGKEVSRTQGRPLGA
DFRVHFGQ---IFSLQIVNWPESLMLQVYE-TVGHSGTTLLA-EVFLPIPETTVVTGRAP
IE-EVEFSSNQHVALDHEGVGSGVPLSFEADGSNQLILMT-----SGKVSHSVSWAVGEN
GTPLIPPLSQQNTGFRSALKRADAISSIGTSGLTDMKKLAKWAAESKLDPN-DPNNAPLM
QLISVATSGESYVPDFFRLEQLQREFNFVSDEELNRAKRFRLLCLRSQEVPEFRNYKPIP
AYDREIMEKVFQDYEKRLRDRNVIETKGHIDSHRAVVAKYLQQVRESVLNRFLIAKHHFL
LTDLIVEEEVPN-----ISILGL-SLFKLAEQKRPLRPRR-----KGRKKVTAQN-----
--LSDGDIK

PF00168 // ENSGT00510000046611_0_Domain_1 (1210, 1334)

LLVNIIRAYDIPVRRPTTSKFQQPTRSSRTFRERHAASPTTHSPTHSADYP
LGQVLVRPFVEVSFQRTICHTTTAEGPNPSWNEELELPF---RAPNGDYSTTSLQSVKDD
VFINIFDEVLFDVLEDDRERGSG-IHTRIERHWLGCVKIPFSTIYCQARIDGTFKIDIPP
VLLGYSKERSVVTERGFDSVRSLSEGSYITLFITIEPQLVPGESVRE------------K
FDSQEDEKLLQATEKFHAECTLKFPNRQCLTTVIDISGKTVFVTRYLKPLNPPQELLDAY
PNDPQATAELVARYVSLIPFLPDAVSFAGICDLWSTSD---QFLDLLAGDEEEHAVLLCN
YFLSLGKKAWLMMGNAIPEGPTVYVLTREQSHYLIWNPCSGHFYGQFDTFCPLKSVGCLI
GPDN------------------------------------------PEELVYQRTDKAAA
AELQD--RIEKILKEKVMDWRPRHLTRWNRYCTSTLRHFLPLLESSRGEEVEEDHRAELL
RQLGDYRFSGFPLHMPYSELKPLIEAVYSTGVHNIDVPNVEFALAVYIHPYPKNVLSVWI
YVASLIRNR

-----------MNPREEKVKIITEEFIENDED----ADMGGQK-------RNSKVRRQP-
-RKKQPPTA-VPKEMVSKESHFGNQP------E--------PVQEEPKTHLLSMTVRRGP
R----------SLPPIPSTS-RTGFAEFSMRGRMREKLQAARSKAESALLQEIPTPRPRR
LRSPS-KKELETE--FGTEPGKEVERTQQEI-DSQSYSRVKFHDSARKIKPKPQVPPGFP
SPEEAYNFFTFNFDHEPEESEEKP---KARHRAGTNQGEEEG--EEEEPTARGRG---KE
MDEEELLNGDDAEDFLLGLDHMADDFVAVRPADYESIHDRLQMETEMLFIPSRQT----V
PTYKKLPENV-QPR-FLEDEGLYTG-VRPEVAHTNQNIMENRLLMQDPERRWFGDDGRIL
ALPNPIKPFPSRRPVLTQEQSIKAELETLYKKAVKYVHS-SQHMIRSGDPP--GNFQLDI
-DISGLIF-THHPCF-SREHVLAAK----LAQLHDQYLA---------------------
----------RHQRNKAKFLTDKLQALRNAVQTGIDPEKPHSSLDTIQKTINEYKSEIRQ
TRKFRDAEQEKDRTLLKTIIKVWK-EMKSLREFQRFTNTPLKLVLRKEKVDQKADE----
----------EAYEAEIQAEI-SELLEEHTEEYAQKM-EEYRTSLHQWKAWRKAQRAKKK
KR---KQAAEDHP-----DDEIEEPHPEEDFVKPTPPEPTNRAVIEQEVRERAAQSRRRP
W-

PF15625 // ENSGT00510000046611_0_Domain_0 (783, 967)

EPTLVPELSLAGSVTPNDQ-CPRAEVSRREDVKKRSVYLKVLFNNKEVSRTVSRPLGA
DFRVHFGQ---IFNLQIVNWPQSLTLQVYE-TIGHSSPTLLA-EVFLPIPETTVVTGRAP
IE-EVEFSSNQHVTLDHEGVGSGVPFSFEADGSNQLILMT-----SGKVSHSVAWAIGEN
GIPLIP

ENSGT00510000046611_0_Linker_0_1 (967, 1210)

PLSQQNIGFRSALKRADAISSIGTSGLTDMKKLAKWAAESKLDPN-DPNNAPLM
QLISVATSGESYVPDFFRLEQLQQEFNFVSDQELNRSKRFRLLRLRSQKVPEFRNYKQVP
VYDREIMEKVFQDYEKRLRDRSVIETKEHIDTHRAIVAKYLQQVRESVINRFLIAKQYFL
LADMIVEEEVPNIS-----ILGL-SLFKLAEQKRPLRPRR-----KGRKKVTAQN-----
--LSDGDIK

PF00168 // ENSGT00510000046611_0_Domain_1 (1210, 1375)

LLVNIVRAYDIPVRKPAMSKFQQPSKSSRMFSEKRAASPSTHSPTHNAAYP
LGQVLVRPFVEVSFQRTVCHTTTAEGPNPSWNEELELPF---RAPNGDYSTASLQSVKDT
VFINIFDEVLHDVLEDDRERGSG-IHTRIERHWLGCVKIPFSTIYFQARIDGTFKIDIPP
VLLGYSKERNMILERGFDSVRSLSEGSYITLFITIEPQLVPGESIRE------------K
FESQEDEKLLQATEKFQAECALKFPNRQCLTTVIDISGKTVFITRYLKPLNPPQELLNVY
PNNLQATAELVARYVSLIPFLPDTVSFGGICDLWSTSD---QFLDLLAGDEEEHAVLLCN
YFLSLGKKAWLLMGNAIPEGPTAYVLTWEQGHYLIWNPCSGHFYGQFDTFCPLKNVGCLI
GPDNIWFNIQRYDSPLRINFDVTKPKLWKSFFSRS-LPYPGLSSVQPEELIYQRSDKAAA
AELQD--RIEKILKEKIMDWRPRHLTRWNRYCTSTLRHFLPLLEKSQGEDVEDDHRAELL
KQLGDYRFSGFPLHMPYSEVKPLIDAVYSTGVHNIDVPNVEFALAVYIHPYPKNVLSVWI
YVASLTRNR

------------------------------------------------------------
--------------MVSEKSHVDSQQ------E--------PRQEEPETGLLNMPARRGP
R----------SLPPIPSAS-RTGFAEFSMRERMREKLQAARSKAESALLQEIPTPRPRR
LRSPK-ERESETE--FGTEPGKEVQSIQQKD-DAQSYSRVKFREQ--KIKSKSQAPPDFP
SAEEAYNFFTFNFDPEPEEPEEKT---KMKARDGTSQEEEAG--EEEEPPVQGG----SK
MDEEGLLNGKDAEDFLLGLEHVANDFVAVRPADYESVHVWLQKEKEILFIPSRLT----V
PTYKKLPENV-QPR-FLEDEGLYIG-ARPEVAPTNQNIMENRLLVQEPGRRWFGDDGRIL
ALPSPIRPFPCRPLLSTREQSTKAELETLYRKAVKYVHS-SKHMVGSGDPP--GNFQLDI
-DISGLLF-THHPCF-SREHVLAAK----LAQLYDQYLA---------------------
----------RQQRNKAKFLTDKLQALRNAVQASLSPETPQQSLDTNQKTIKEYKYEIRQ
TRKLRDAEQEKDRNLLKTLIKVWK-EMKSLREFQRFTNTPLKLVLRKEKFDQKADE----
----------EAYEAEIQAEI-NELLEEHTEEYEQKM-EEYRASYQQWKAWKKAQRAKKR
KK---KEAAEEHP-----EEEAEEAPPGEEPVKPVPPEPTDPGELEQKVRERAAHSRRR

PF15625 // ENSGT00510000046611_0_Domain_0 (780, 967)

P
G-EPLLLPELSLAGSVTPNEQ-CPRVEVLRREDVRRRCVYLKVLFNNKEVSRTVSRQLGA
DFRVHFGQ---IFNLQIFNWPESLTLQVYE-TIGHSSTTLLA-EVFLPIPETTVVTGRAP
IE-EVEFSSNQHVTLDHEGVGSGVPFSFEADGSNQLTLMT-----SGKVSHSVAWAVGEN
GIPLIP

ENSGT00510000046611_0_Linker_0_1 (967, 1211)

PLSQQNIGFRSALKRADAISSIGTSGLTDMKKLAKWAAESKLDPN-DPNNAPLM
QLISVATSGESYVPDFFRLEQLQQEFNFVSDEELNRSKRFRLLCLRSQEVPEFRNYKQIP
VYDREIMEKIFQEYEKRLRDRNVIETKDHIDTHRAIVAKYLQQVRDSVINRFLVAKHHFL
LTDLVVEEEVPNISSEGSGILGL-SLFKLAEQKRPLRPRR-----KGRKKVTAQN-----
--LSDGDIKL

PF00168 // ENSGT00510000046611_0_Domain_1 (1211, 1375)

LVNIVRAYDIPVRKPPASKFQPPSRSARAFSEKHVASPSTHSPAHSPDYA
LGQVLVRPFVEVSFQRTICHTTTAEGPNPSWNEELELPF---RAPNGDYSTASLQSVKDD
VFINIFDEVLYDVSEDDRERGSG-IHTRIERHWLGCVKIPFSTIYFQARIDGTFKIDIPP
VLLGYSKERNMILERGFDSVRSLSEGSYITLFITIEPQLVPGESVREKLS-----MLK-K
FESQEDEKLLQATEKFQAECALKFPNRQCLTTVIDISGKTVFVTRYLKPLNPPKELLNAY
PSNPQATAELVARYVSLIPFLPDTVSFASICDLWSTSD---QFLDLLAGDEEEHAVLLCN
YFLFLGKKAWLVMGNAIPEGPTAYVLTWEQNHYLIWNPCSGHFYGQFDTFCPLKSVGCLI
GPDNIWFNIQQYDSPLRINFDVTKPKLWKSFFSRS-LPYPGLSSVQPEELIYQRTDKAAA
AELQD--RIEKILKEKIMDWRPRHLTRWNRYCTSTLRHFLPLLERSQGEDVEDDHRAELL
KQLGDYRFSGFPLHMPYSEVKPLIEAVYSTGVHNIDVPNVEFALAVYIHPYPKNVLSVWI
YVASLIRNR

-----------MNPREEKVKIITEEFIENDED----ADMGRQK-------RNSKVRRQP-
-RKKQPPTA-LPKEMVSEESHLGNQP------E--------PVQEEPKTHLLSMTVRRGP
R----------SLPPIPSTS-RTGFAEFSMRGRMREKLQAARSKAESALLQEIPTPRPRR
LRSPS-KKELETE--FGTEPGKEVESTQQEI-DSRSYSRVKFRDSARKIKPKPQVPPGFP
SPEEAYNFFTFSFDPEPEESEEKP---KARHRAGTNQEEEEG--EEEEPPARGRG---KE
MDEEELLNGDDAEDFLLGLDHMADDFVAVRPADYESIHDRLQMETEMLFIPSRQT----V
PTYKKLPENV-QPR-FLEDEGLYTG-VRPEVARTNQNIMENRLLMQDPERRWFGDDGRIL
ALPNPIKPFPSRRPVLTQEQSIKAELETLYKKAVKYVHS-SQHMIRSGDHP--GNFQLDI
-DISGLIF-THHPCF-SREHVLAAK----LAQLYDQYLA---------------------
----------RHQRNKAKFLTDKLQALRNAVQTGVDPEKPHSSLDTIQKTINEYKSEIRQ
TRKFRDAEQEKDRTLLKTIIKVWK-EMKSLREFQRFTNTPLKLVLRKEKIDQKADE----
----------EAYEAEIQAEI-SELLEEHTEEYAQKM-EEYRTSLHQWKAWRKAQRAKKK
KR---KQAAEDHP-----DDEIEEPHPEEDLVKPTPPEPTDRAVIEHEVRERAAQSRRRP
W-

PF15625 // ENSGT00510000046611_0_Domain_0 (783, 967)

EPTLVPELSLAGSVTPSDQ-CPRAEVSRREDVKKRSVYLKVLFNNKEVSRTVSRPLGA
DFRVHFGQ---IFNLQIVNWPESLTLQVYE-TIGHSSPTLLA-EVFLPIPETTVVTGRAP
IE-EVEFSSNQHVTLDHEGVGSGVPFSFEADGSNQLILMT-----SGKVSHSVAWAIGEN
GIPLIP

ENSGT00510000046611_0_Linker_0_1 (967, 1210)

PLSQQNIGFRSALKRADAISSIGTSGLTDMKKLAKWAAESKLDPN-DPNNAPLM
QLISVATSGESYVPDFFRLEQLQQEFNFVSDQELNRSKRFRLLRLRSQEVPEFRNYKQVP
VYDREIMEKVFQDYEKRLQDRSVIETKEHIDTHRAIVAKYLQQVRESVINRFLIAKQYFL
LADMIVEEEVPNIS-----ILGL-SLFKLAEQKRPLRPRR-----KGRKKVTAQN-----
--LSDGDIK

PF00168 // ENSGT00510000046611_0_Domain_1 (1210, 1375)

LLVNIVRAYDIPVRKPAVSKFQQPSKSSRMFSEKRAASPSTHSPTHNADYP
LGQVLVRPFVEVSFQRTVCHTTTAEGPNPSWNEELELPF---KAPNGDYSTASLQSVKDI
VFINIFDEVLHDVLEDDRERGSG-IHTRIERHWLGCVKIPFSTIYFQARIDGTFKIDIPP
VLLGYNKERNMILERGFDSVRSLSEGSYITLFITIEPQLVPGESIREKMSN----MLK-K
FESQEDEKLLQATEKFQAECALKFPNRQCLTTVIDISGKTVFITRYLKPLNPPQELLNVY
PNNLQATAELVARYVSLIPFLPDTVSFGGICDLWSTSD---QFLDLLAGDEEEHAVLLCN
YFLSLGKKAWLLMGNAIPEGPTAYVLTWEQGHYLIWNPCSGHFYGQFDTFCPLKNVGCLI
GPDNIWFNIQRYDSPLRINFDVTKPKLWKSFFSRS-LPYPGLSSVQPEELIYQRSDKAAA
AELQD--RIEKILKEKIMDWRPRHLTRWNRYCTSTLRHFLPLLEKSQGEDVEDDHRAELL
KQLGDYRFSGFPLHMPYSEVKPLIDAVYSTGVHNIDVPNVEFALAVYIHPYPKNVLSVWI
YVASLIRNR

MRTGSRWQCRITNPRELPLSSLQARIPFPSEPVANPWLRGCWLSLPRLCKSSSLGWDEI-
-NLCEPPTA-GPKEMLSEKAHGGSQQEL--------------GQEEPETHLLSVPARRGA
R----------GLPPIPSVS-RTGFAEFSMRERLREKLQAARSKAESVLLQDIPTPRPRR
LRSPT-EKESETG--FGTEPSKEIQAAPHED-DSQSYSRAKFRDAARKIKSKPQAPPGFP
SAEEAYNFFTFNFDPEPEKPTEKA---KAKDRDGTNQEE--DEGEEEESPAG----GVNK
TDEEELLSGKEAKDFLLGLDAAADDFVAVQPAEYESIHTWLEKEKEMLFIPSRQA----V
PTYKKLPENV-QPR-FLEDEGLYTG-ARPEVARASQNIAENRLLRQEHGRKWFGDDGRIL
ALPSPIKPFPSRPPPLAQEPRAMAGLETLYKKAVKYVHR-TQHMIGSGDPP--GNFQLDI
-DISGLIF-THHPCF-SREHVLAAK----LAQLYDQYLA---------------------
----------RHQRNKAKFLTDKLQALRNAVRTGLHPEKPHQSLDATQKTIDEYKSEIRE
TRKLRDAEQEKDRTLLKTIIKVWK-EMKSLREFQRFTNTPLKLVLRKEKVDQKADE----
----------EAYEAEIQAEI-REWMEEHTEEYEQKM-EDYRASYQQWKAWKKAQKAKKK
KKKQ----AEEHPE----EETEEEPYPGEEPVKPVPPGPPDQAVLEQQAREHAAHTRRR

PF15625 // ENSGT00510000046611_0_Domain_0 (780, 967)

P
G-EPMLLPELSLAGSVTPSDQ-CPRAEVLRREDVKRRLVYLKVLFNSKEVSRTVSRQLGA
DFRVHFGQ---IFNLQIFNWPESLTLQVYE-TVGHTSTALLA-EVFLPIPETTIVTGRAP
LE-EVEFSSNQHVTLDHEGVGSGVPFSFEADGSNQLILMT-----SGRVSHSVTWAVGEN
GTPLIP

ENSGT00510000046611_0_Linker_0_1 (967, 1210)

PLSQQNIGFRSALKRADAISSIGTSGLMDMKKLAKWAAESKLDPN-DPNNAPLM
QVISVATSGESYVPDFFRLEQLQQEFNFVTSEELNRSKRFRLLHLRSQEVPEFRNYKQIP
AYDREIMEKVFQDYEKRLRDKSVIETKDHIDTHRAIVAKYLQQVRESVVNRFLIAKHHFL
LADLVVEEEVPNIS-----ILGL-SLFKLAEQKRPLRPRR-----KGRKKVTAQN-----
--LSDGDIK

PF00168 // ENSGT00510000046611_0_Domain_1 (1210, 1375)

LLVNICRAYDIPVRKPTASKSQQPARASRTLGEKHAASPSAHS----PDSP
LGQVLVRPFVEVSFQRTVCHTTTAEGPNPSWNEELEFPF---RAPNGDYSTASLQSVKDD
VFINIFDEVLHDILEDDRERGSG-IHTRIERHWLGCVKFPFSTIYSQARIDGTFKIDIPP
VLLGYSKERNMIIERGLDPVRSLSESSYITLFITIEPQLVPGESVRE------------K
FDSQEDEKLLQATEKFQTECALKFPNRQCLTTVIDINGKTVFITRYLKPLNPPQELLNAY
PNNPQATAELVARYVSLIPFLPDTVSFAGVCDLWSTSD---QFLDLLAGDEEEHAVLLCN
YFLFLGKKAWLVMGNAIPEGPTAYVLTWEQNHYLIWNPCSGHFYGQFDTFCPLKSVSCLI
GPDNIWFNIQQYDSPLRINFDVTKPKLWKSFFSRK-LPYPGLSSVQPEELIYQHTDKAAA
AELQD--RIEKMLKEKIMDWRPRHLTRWNRHCTSTLRHFLPLLERSHGEDMEDDHRAELQ
KQLGDYRFSGFPLHMPYSEVKPLIEAVYSTGVHNIDVPNAEFALAVYIHPYPKNVLSVWI
YVASLIRNR

-----------MNPKEEKVKIITEEFIENDED----ANVGKRK-------KNSKVQRQP-
-RKKQPPTT-GPDKMMLEESHLGNQQ------E--------LVQDEPQTRLLSVTARRGP
R----------SLPPIPSAS-RTGFAEFSMRERMREKLQAARSKAESALLQEIPTPRPQR
LRSPT-VKELETE--FGTESGKEVGSTQQED-DTQSYARVKFHVSARKIKSKPQVPPGFP
SAEEAYNFFTFTFDPEPEEAEEKP---K--HGDGTHQEEEEG--E-EEPPTEEGA---NR
MDEEELLHGKDAEDFLLGLDHTADEFLAVRPAHYESVHVRLQREKEMLFIPSRLT----V
PTYKKLPENV-QPR-FLEDEGLYIG-ERPEVARTNQNIMENRLLTQESGRRWFGDDGRIL
ALPNPIKPFPSRPPVFMQEQSIKAELETLYKKAVKYVHR-SQHMIGSGDPA--GNFQLDI
-DISGLIF-THHPCF-SREHVLAAK----LAQLYDQYLA---------------------
----------RHQRNKAKFLTDKLQALRNAVQTGLNPEKPHQSLDTIQKTINEYKSEIRQ
TRKLRDAEQERDRTLLKTIIKVWK-EMKSLREFQRFTNTPLKLVLRKEKVDQKTDE----
----------EAYEAEIQAEI-SELLEEHTEEYEQKM-EEYRTSYQQWKAWKKAQRAKKK
KK---KQATEEHP-----EEETEEPYPEEDPVKPSPPEPTDRAAVEQQVRERAAQSRRR

PF15625 // ENSGT00510000046611_0_Domain_0 (780, 967)

P
G-EPTLLPELSLAGSVTPNDQ-CPRAEVWRREDVKRRSVYLKVLFNNKEVSRTVSRQLGT
DFRVHFGQ---IFNLQIFNWPESLTLQVYE-TVGHSSPTLLA-EVFLPIPETTIVTGRAP
IE-EVEFSSNQHVTLDHEGVGSGVPFSFEADGSNQLILMT-----SGKVSHSVAWAIGEN
GIPLIP

ENSGT00510000046611_0_Linker_0_1 (967, 1210)

PLSQQNIGFRSALKRADAISSIGTSGVTDMKKLAKWAAESKLDPN-DPNNAPLM
QLISVATSGESYVPDFFRLEQLQQEFNFVSDEELNRSKRFRLLHLRSQQVPEFRNYKQIP
VYDREIMEKVFQDYEKRLRDRNVIETKDHIDTHRAVVAKYLQQVRESVINRFLIAKQHFL
LADLVVEEEVPNIS-----ILGL-NLFKLAEQKRPLRPRR-----KGRKKVTAQN-----
--LSDGDIR

PF00168 // ENSGT00510000046611_0_Domain_1 (1210, 1375)

LLVNIIRAYDLPVRKPTASKFQQPSRSSRTFREKHAASPDTRSPTHSADYP
LGQVLVRPFVEVSFQRTICHTTTAEGPNPSWNEELELPF---RAPNGDYSTASLQSVKDV
VFINIFDEVLYDVLEDDRERGNG-IHTRIERHWLGCVKIPFSTIYFQARIDGTFKIDIPP
VLLGYSKEQNMIIERDFDSVRSLSEGSYITLFITIEPQLVPGESVRE------------K
FDSQEDEKLLQATEKFQAECALKFPKRQCLATVIDISGKTVFITRYLKPLNPPQELLNIY
PNNPQATAELVARYVSLIPFLPDTVSFAGLCDLWSTSD---QFLDLLAGDEEEHAVLLCN
YFLFLGKKAWLVMGNAIPEGPTAYVLTWEKSHYLIWNPCSGNFYGQFDTFCPLKNVGCLI
GPDNIWFNIQQYDSPLRINFDVTKHKLWKSFFSRS-LPYPGLSSVQPEELIYQNTDKAAA
AELQD--RIEKILKEKIMDWRPRHLTRWNRYCTSTLRHFLPLLESSQGEDIEDDHRAELL
KQLGDYRFSGFPLHMPYSEVKPLIDAVYSTGVHNIDVPNVEFALAVYIHPYPKNVLSVWI
YVASLIRNR

-----------MNPREEKVKIITEEFIENDED----ADMGRQK-------RNSKVRRQP-
-RKKQPPTA-LPKEMVSEESHLGNQP------E--------PVQEEPKTHLLSMTVRRGP
R----------SLPPIPSTS-RTGFAEFSMRGRMREKLQAARSKAESALLQEIPTPRPRR
LRSPS-KKELETE--FGTEVRNTLSTLSLK-----------------PKACLYRVPPGYP
SPEEAYNFFTFSFDPEPEESEEKP---KARHRAGTNQEEEEG--EEEEPPARGRG---KE
MDEEELLDGDDAEDFLLGLDHMADDFVAVRPADYESVHDRLQMETEMLFIPSRQT----V
PTYKKLPENV-QPR-FLEDEGLYTG-VRPEVARTNQNIMENRLLMQDPERRWFGDDGRIL
ALPNPIKPFPSRRPVLTQEQSIKAELETLYKKAVKYVHS-SQHMIRSGDHP--GNFQLDI
-DISGLIF-THHPCF-SREHVLAAK----LAQLYDQYLA---------------------
----------RHQRNKAKFLTDKLQALRNAVQTGVDPEKPHSSLDTIQKTINEYKSEIRQ
TRKFRDAEQEKDRTLLKTIIKVWK-EMKSLREFQRFTNTPLKLVLRKEKVDQKADE----
----------EAYEAEIQAEI-SELLEEHTEEYAQKM-EEYRTSLHQWKAWRKAQRAKKK
KR---KQAAEDHP-----DDEIEEPHPEEDLVKPTPPEPTDRAVIEHEVRERAAQSRRRP
W-

PF15625 // ENSGT00510000046611_0_Domain_0 (783, 967)

EPTLVPELSLAGSVTPSDQ-CPRAEVSRREDVKKRSVYLKVLFNNKEVSRTVSRPLGA
DFRVHFGQ---IFNLQIVNWPESLTLQVYE-TIGYSSPTLLA-EVFLPIPETTVVTGRAP
IE-EVEFSSNQHVTLDHEGVGSGVPFSFEADGSNQLILMT-----SGKVSHSVAWAIGEN
GIPLIP

ENSGT00510000046611_0_Linker_0_1 (967, 1210)

PLSQQNIGFRSALKRADAISSIGTSGLTDMKKLAKWAAESKLDPN-DPNNAPLM
QLISVATSGESYVPDFFRLEQLQQEFNFVSDQELNRSKRFRLLHLRSQEVPEFRNYKQVP
VYDREIMEKVFQDYEKRLQDRSVIETKEHIDTHRAIVAKYLQQVRESVINRFLIAKQYFL
LADMIVEEEVPNIS-----ILGL-SLFKLAEQKRPLRPRR-----KGRKKVTAQN-----
--LSDGDIK

PF00168 // ENSGT00510000046611_0_Domain_1 (1210, 1375)

LLVNIVRAYDIPVRKPAVSKFQQPSKSSRMFSEKRAASPSTHSPTHNADYP
LGQVLVRPFVEVSFQRTVCHTTTAEGPNPSWNEELELPF---KAPNGDYSTASLQSVKDT
VFINIFDEVLHDVLEDDRERGSG-IHTRIERHWLGCVKIPFSTIYFQARIDGTFKIDIPP
VLLGYNKERNMILERGFDSVRSLSEGSYITLFITIEPQLVPGESIRE------------K
FESQEDEKLLQATEKFQAECALKFPNRQCLTTVIDISGKTVFITRYLKPLNPPQELLNVY
PNNLQATAELVARYVSLIPFLPDTVSFGGICDLWSTSD---QFLDLLAGDEEEHAVLLCN
YFLSLGKKAWLLMGNAIPEGPTAYVLTWEQGHYLIWNPCSGHFYGQFDTFCPLKNVGCLI
GPDNIWFNIQRYDSPLRINFDVTKPKLWKSFFSRS-LPYPGLSSVQPEELIYQRSDKAAA
AELQD--RIEKILKEKIMDWRPRHLTRWNRYCTSTLRHFLPLLEKSQGEDVEDDHRAELL
KQLGDYRFSGFPLHMPYSEVKPLIDAVYSTGVHNIDVPNVEFALAVYIHPYPKNVLSVWI
YVASLIRNR

-----------MNPKEEKVKIISQEFTEDGVEVDAE---VERR-------KKSRIQRQQ-
-KKKKP-PTTAPEEMVSDKSHEEYQQKMQE-----------TVEEEPESHLLSVTTRRGP
R----------SLPPIPSAS-RTGFAEFSMRERMREKLQAARSKAESALLQEIPTPRPRR
LQSPS-ERESETE--FGPEPSKEVQGTRQED-DSQSCSRVKFRDSVRKIKSKPQAPAGFP
SAEEAYNFFTFNFDHEPEEPEDKS---NAKDRDRAQE--DEGREEE--T----PAGRAKK
TEEEELLNGKDAEDFLLGLDPTVHNVVAVKPAEYKSAHVRLQKEKETLFTPSRLA----G
TCSVYFPAQL-GHVHFREDEIRLAGIKGLAVSRAGTNFSSD---LIIKVGKWFGDDGRIL
ALPSPIKPFPSRPSLSTQEQSAKAELETLYKKAMKYVHS-NQRMIGSGDPP--GNFQLDI
-DISGLIF-THHPCF-SREHVLASK----LALLYDQYLA---------------------
----------RQQRNKAKFLTDKLQALRNAVQRGFNPEEPHQTLDATQKTINEYKSEIRQ
TRKLRDTEQEKDRTLLKTLLKVWK-EMKSLREFQRFTNTPLKLVLRKGKVDQKADE----
----------EAYEAEIQAEI-QELLEEHTEDYKKKM-EEYRASHQQWKAWRKAQRAKKK
KKKKAA---EE----HTDEEEAEEPFPEEDVVKPIPPEPTDPGLIEQQVRERAAHSRRR

PF15625 // ENSGT00510000046611_0_Domain_0 (780, 962)

P
G-EPMLVPELSLAGNVTPSDQ-CPRVEVSRREDVKRRSVYLKVLFNGKEVSRTVTRQLGA
DFRVHFGQ---IFNLQIFNWPESLMLQVYE-TVGHSSTTLLA-EVFLPIPETTIVTGRAP
ME-EVEFSSNQHVTLDHEGVGSGVPFSFEADGSNQLTLMT-----SGKVSHSVAWAIGEN
A

ENSGT00510000046611_0_Linker_0_1 (962, 1210)

FF---------------------------------------------------------
-----SLFGESYVPDFFRLEQLQQEFNFVSDEELNRSKRFRLLHLRSQEVPEFRNYKQIP
VYDREIMEKVFQDYEKRLRDRNVIETKDHLDTHRATVAKYLQQVRESVINRFLIAKHHFL
LTDLVVEEEVPNISSEGSGILGL-SLFKLAEQKRPLRPRR-----KGRKKVTAQN-----
--LSDGDIK

PF00168 // ENSGT00510000046611_0_Domain_1 (1210, 1375)

LLVNIIRAYDIPVRKPMVSKFQQPSRSSRTFNEKHSASPSGHSPGHSADYP
LGQVLVRPFVEVSFQRTICHTTTAEGPNPSWNEELELPF---RAPNGDYSTASLQSVKDD
VYINIFDEVLYDVLEDDRERGSG-IHTRIERHWLGCVKIPFSTIYFQARIDGTFKIDIPP
VLLGYSKERHIIMERAFDSARSLSEGSYITLFITIEPQLVPGEPIREKTTD----MLK-K
FDSQEDEKLLQAAEKFQAECNLKFPCRHCLTTVIDLSGKTVFITRYLKPLNPPQELLNVY
PNNPQATAELVARYVSLIPFLPDTVSFAGICDLWSTSD---QFLDLLAGDEEEHAVLLCN
YFLSLDKKAWLVMGSAIPEGPTAYVLTWEKNHYLIWNPCSGHCYGQFDTFCPLKSVSCLI
GPDNIWFNIQHYDSPLRINFDVTKPKLWKSFFSRS-LPYPGLSSVQPEELLYQHTDKAAA
AELQD--RIEKILKEKIMDWRPRHLTRWNRYCTSTLRHFLPLLERSQGEGIEEDHRAELL
KQLGDYRFSGFPLHMPYSEVKPLIEAVYSTGVHNIDVPNVEFALAVYIHPYPKNVLSVWI
YVASLIRNR

-----------MNPREEKVSIITEESTANDED----AEVGRRE-------KSSKVQRQQ-
-RKKQPPRA-DSEEMVTGKA------QP--------------GQEEPEMHLLSMPARRGP
R----------SLPPIPSMS-RTGFAEFSMRERLREKLQAARSKAESALLQEIPTPRPRR
LRSPS-EKELETE--FGPEPCKESQATSHRN-DSQSYSRVKFHDAVQKIKSKPQAPPGFP
SAEEAYNFFTFSFDPEPEEPTVKA---RAKNRDGTHQE-EE---GEEESPAG----GMNK
MDEEELLGSQDAKDFLLGLDPAPDEFVVVRPAEYEGTHTWLEKEKELLFFPSRRA----V
PTWKKLPENV-QPR-FLEDEGLYTG-ARPEVARAQQNVVENRLLRQEPERKWFGDDGRIL
ALPSPIKPFSSRPRPLAQEPSAQAGLETHYKKAVKYVHR-TQHVVGSADPP--GSFQLDI
-DISGLIF-THHPCF-SREHVLAAK----LAQLYDQYLA---------------------
----------RHQRSKAKFLTDKLQALRNAVQTGLYPEKPHQSLDATQKTIKEYKSEIRE
TRKLRDAEQEKDRTLLKTIVKVWK-EMKSLREFQRFTNTPLKLVLRKEKVDQKADE----
----------EAYEAEIQAEI-SELMEEHTEEYEQRL-GEYRASYQQWKAWKKAQKAKKK
KKKQ----AEEHPE----GEAEEELYPGEEPVKPIPPELLDHAVLEQQARERAAHSRRR

PF15625 // ENSGT00510000046611_0_Domain_0 (780, 967)

P
G-EPVLLPELSLTGSVTPDDQ-CPRAEVLRREDVKRRSVYLKVLFNSKEVSRTVSRQLGA
DFCVHFGQ---IFNLQIFNWPESLTLQVYE-TVGHSSTTLLA-EVFLPIPETTTVTRRAP
VE-EVEFSSSQHVTLDHEGVGSGVPFSFEADGSNQLILMT-----SGRVSHSVAWATGDN
GTPLIP

ENSGT00510000046611_0_Linker_0_1 (967, 1253)

PPSQQSLGFRSALKRADAISSIGTSGLTDMKKLAKWAAESKLDPN-DPNNAPLM
QLISIATSGESYVPDFFRLEQLQQEFNFVTSEELNRSKRFRLLCLRSQEVPEFRNYKQIP
AYDREILEKVFQDYEKRLRDKSVIETKDHIDTHRAIVAKYLQQVRESVVNRFLIAKHHFL
LSDLVVEEEVPNMSSEGSGILGL-SLFKLAEQKRPLRPRR-----KGRKKVTAQN-----
--LSDGDIKLLVNICRAYDIPVRKPPASKSQQPARSSRTFSDRHAASPGAHS

PF00168 // ENSGT00510000046611_0_Domain_1 (1253, 1375)

PPHSPDTP
LSQVSVRPFVEVSFQRTICHTTTAEGPNPSWNEELEFPF---RAPNGDYSTASLQSVKDD
VFINIFDEVLHDILEDDRERGSG-IHTRIERHWLGCVKIPFSTIYSQARIDGTFKINTPP
VLLGYSKERNVLLERGLDSVRSLSEGSYLTLFITIEPQLVPGESVREKTSD----LLK-K
FDSQEDEKLLQATEKFQAECALKFPTRQCLTTVTDISGKTVFVTRYLKPLNPPEELLNVY
PNNPQATAELVARYVSLIPFLPDTVSFAGICDLWSTSD---QFLDLLAGDEEEHAVLLCD
YFLFLGKKAWLVMGNAIPEGPTAYVLTWEQNHYLIWNPCSGHFYAQFDTFCPLKSVSCLI
GPDNIWFNIQQYDSPLRINFDVTKPKLWKSFFSRS-LPYPGLSSVQPEELIYQRTDKAAA
AELQD--RIEKMLKEKIMDWRPRHLTRWNRHCTSTLRHFLPLLERSQGEDVEDEHRAELQ
KQLGDYRFSGFPLHMPYSEVKPLIEAVYSTGVHNTDVPNVEFALAVYIHPYPKNVLSVWI
YVASLIRNR

-----------MNPREEKVKIITEEFIENDED----ADMGRQK-------RNSKVRRQP-
-RKKQPPTA-LPKEMVSEESHLGNQP------E--------PVQEEPKTHLLSMTVRRGP
R----------SLPPIPSTS-RTGFAEFSMRGRMREKLQAARSKAESALLQEIPTPRPRR
LRSPS-KKELETE--FGTEPGKEVESTQQEI-DSRSYSRVKFRDSARKIKPKPQVPPGFP
SPEEAYNFFTFSFDPEPEESEEKP---KARHRAGTNQEEEEG--EEEEPPARGRG---KE
MDEEELLNGDDAEDFLLGLDHMADDFVAVRPADYESIHDRLQMETEMLFIPSRQT----V
PTYKKLPENV-QPR-FLEDEGLYTG-VRPEVARTNQNIMENRLLMQDPERRWFGDDGRIL
ALPNPIKPFPSRRPVLTQEQSIKAELETLYKKAVKYVHS-SQHMIRSGDHP--GNFQLDI
-DISGLIF-THHPCF-SREHVLAAK----LAQLYDQYLA---------------------
----------RHQRNKAKFLTDKLQALRNAVQTGVDPEKPHSSLDTIQKTINEYKSEIRQ
TRKFRDAEQEKDRTLLKTIIKVWK-EMKSLREFQRFTNTPLKLVLRKEKVDQKADE----
----------EAYEAEIQAEI-SELLEEHTEEYAQKM-EEYRTSLHQWKAWRKAQRAKKK
KR---KQAAEDHP-----DDEIEEPHPEEDLVKPTPPEPTDRAVIEHEVRERAAQSRRRP
W-

PF15625 // ENSGT00510000046611_0_Domain_0 (783, 967)

EPTLVPELSLAGSVTPSDQ-CPRAEVSRREDVKKRSVYLKVLFNNKEVSRTVSRPLGA
DFRVHFGQ---IFNLQIVNWPESLTLQVYE-TIGHSSPTLLA-EVFLPIPETTVVTGRAP
IE-EVEFSSNQHVTLDHEGVGSGVPFSFEADGSNQLILMT-----SGKVSHSVAWAIGEN
GIPLIP

ENSGT00510000046611_0_Linker_0_1 (967, 1210)

PLSQQNIGFRSALKRADAISSIGTSGLTDMKKLAKWAAESKLDPN-DPNNAPLM
QLISVATSGESYVPDFFRLEQLQQEFNFVSDQELNRSKRFRLLRLRSQEVPEFRNYKQVP
VYDREIMEKVFQDYEKRLRDRSVIETKEHIDTHRAIVAKYLQQVRESVINRFLIAKQYFL
LADMIVEEEVPNIS-----ILGL-SLFKLAEQKRPLRPRR-----KGRKKVTAQN-----
--LSDGDIK

PF00168 // ENSGT00510000046611_0_Domain_1 (1210, 1375)

LLVNIVRAYDIPVRKPAVSKFQQPSKSSRMFSEKRAASPSTHSPTHNADYP
LGQVLVRPFVEVSFQRTVCHTTTAEGPNPSWNEELELPF---KAPNGDYSTASLQSVKDI
VFINIFDEVLHDVLEDDRERGSG-IHTRIERHWLGCVKIPFSTIYFQARIDGTFKIDIPP
VLLGYNKERNMILERGFDSVRSLSEGSYITLFITIEPQLVPGESIRE------------K
FESQEDEKLLQATEKFQAECALKFPNRQCLTTVIDISGKTVFITRYLKPLNPPQELLNVY
PNNLQATAELVARYVSLIPFLPDTVSFGGICDLWSTSD---QFLDLLAGDEEEHAVLLCN
YFLSLGKKAWLLMGNAIPEGPTAYVLTWEQGHYLIWNPCSGHFYGQFDTFCPLKNVGCLI
GPDNIWFNIQRYDSPLRINFDVTKPKLWKSFFSRS-LPYPGLSSVQPEELIYQRSDKAAA
AELQD--RIEKILKEKIMDWRPRHLTRWNRYCTSTLRHFLPLLEKSQGEDVEDDHRAELL
KQLGDYRFSGFPLHMPYSEVKPLIDAVYSTGVHNIDVPNVEFALAVYIHPYPKNVLSVWI
YVASLIRNR

------------------------------------------------------------
------------------------------------------------------------
------------LPPVPSTS-RMGFSELSIRERMREKLRAARSKAEASLSQEDLGPRPRH
LKSIRQ-RKAELRLDKGVQAGDKLGE--MQRDESLLSSKMKFSDSVKELKQKSQAQNDYP
SAEEAYNFFTLSFDPEPEGIKAGA-----RKRSELNEEE--AE---EYVETNEEEQEEDE
MDEDALL---VKDTDLFIMGQTDEDFLVMKPADCERYSEQLQKEKEFLFVPSMQT----V
PTSQKMPENV-QPR-YIEDEGLYAE-ERPFVSPSNQNILENRILRQEQGKEWFGDDGRIL
ALPNPIRQSSTRPPVFSLEEGIAPELETIYRKAIKTTAA-NQYLVGPGDFQ--GPFQLDI
-DISGLIF-THHPCF-SREHVLAAK----LAQLYDQYLA---------------------
----------RKQKNLTELLTDKLRALRNAVQCSADS--AGASGPTAQQSIPEYKIEIRQ
TRRLRDAEQEKDRMLLKSIIKVWK-EMKSLREFQKFTNTPMKLCLRKEEVDHRSDE----
----------KAYEAEIQAEI-SELQEEYMEEYEKKM-EEYKSELQEWKSWKKAQKSKKK
KKRKDLQ------E---E-ESVEDYDLGEEPMKPIPPKMVDSLEIEQQVREKANNFRRKP
G-EPALIPELVLSGSITPSEQ-CPRAEVLRREDVNKRSAFIKVFFNSKEVSRTVTRPLSS
DFRVHFGQ---IFNLQIFNWPESLKLQIYE-TTGLSSTTLLA-EVFIPVPETTVLTGSAP
ME-EIEFSSNQRVRLDHEGVGSDVSFSFEADGSNQMTLMT-----SGKVSNSVSWAVGEK
GIPLIPPVSQQNTGIPSALKNIDAIASIGTSGLTDMKKLAKWAAETKLDPN-DPNNAALM
QMIMVASSGEANIPDFFRLEQLQQEFNFVSDEEFNRSKRFRLLQLRNEEVAEFRNYKQVP
LHEREISEKLFQEYEKRLRERDVIDNKHYLDARRAVVASYLQKVRESVINRFLIAKHHFL
LSDLVNEEEIPTLGSEGPGILGL-GLFKLAEPKRPLKPRR-----KERKKVTAQN-----
--LSDGDIK

PF00168 // ENSGT00510000046611_0_Domain_1 (1210, 1334)

LLVNIIRAYDIPVRKPVTSKL-QPSKSSRSFNEMFAASPSAQSPTNNVDWA
FDQVLVRPFVEVSFQRTVCRTTTAEGPNPNWNEELEFPF---RAPNGDYSTHSLQSVKDE
VFINIFDEVLHDVTEDDRDRGSG-IHTRVERHWLGCVKIPFTTIYFQARIDGTFKVNIPP
VLLGYSKEKNLGMERGYDSVRNLSEGSYITLFITIEPQLVPGESVREKMNE----MLK-K
FDTQEDEKLLQAAEKYEVECTSKFPNRQCLTTVIDLNGKTVFITRYIKPLNPPQELLDAL
PNSSQTTAELVARYVALIPFLPDSVSFAGICDLWCTSD---QFLDLLAGDEEEHAVLLCN
YFLGMGKKAWLVIGNAIPEGQTTYVLTLEQSQYVIWNPSTGCFYRHYDTFCPLQNVYCLI
SCDNIWFNIQQWDSPARISFDISKPKLWKPFFSRS-LPYPGLCSVQPEELVYQHSDKAAA
VELQG--RIEKILKEKIMEWRPRHLTRWNRYCTSTLRNFLPLLEQNQGKDVEDDHQAELQ
KQLGDYRVSGFPIHMPFSEVRPLVEAVHSTGVHTIDVSNVEFALAVYVHPYPQNVLSTWI
YVASLVRNR

-----------MNPKEEKVKIISEEFTVDDGD----TEVGRRK-------KNSKIQRQQ-
-RKKKPPAT-TPEEMVSDKFQGSGQP------E--------MMEEEPETNLLSLTARRGP
R----------SLPPIPSAS-RTGFAEFSMRERMREKLQAARSKAESALLRDAPTPRPRR
LRSSS-ERETETE--FGTEPSEEIGGTQQED-NPQSHARFKFRDSVRKIKSKPQLPPGFP
SAEEAYNFFTFNFDPEPEQSEGKTQA---KGGARAHQEDQEG--E-EGTHVQETT---EK
TEEEELLNGKDAEDFLLGLDPTAHDFVSVRAAEYESAHVRLQKEKEILFTPSRLA----V
PTYKKLPENVLQPR-FLEDEGLYIG-ARPEVARTNENIMENRLLIQEPGRKWFGDDGRIL
ALPSPIKPYPSRPSLSTREQNTKAELETLYKKAVKYVHS-RQRMIGSGDPP--GNFQLDI
-DISGLIF-SHHPCF-SREHVLASK----LAQLYDQYLA---------------------
----------RQQRNKTKFLTDKLQALRKAVQTGLNPETSHQSLDTTQKTINDYKSEIRQ
TRKLRDAEQEKDRALLKTIIKVWK-EIKSLREFQRFTNTSLKLVLRKEKVDQKVDE----
----------DAYESEIQAEI-HELLEEHAEEYTKKM-EEYRALHQQWKAWRKAQRAKKK
KK---KQTAQEPA-----EEEVEEHFPEEEVEKPIPPELTDPAVIEEQVRERVAHSRRR

PF15625 // ENSGT00510000046611_0_Domain_0 (780, 967)

P
G-EPTLVPELSLAGNVTPNDQ-CPRAEVSRREDVRRRSVYLKVVFNSKEVSRTVSRPLGA
DFRVHFGQ---IFNLQIFNWPESLMLQVYE-TIGHSGTTLLA-EVFLPIPETTLVTGRAP
IE-EVEFSSDQHVTLDHEGVGSGVPFSFEADGSNQLTLMT-----SGKVSHSVAWAIGEN
GIPLIP

ENSGT00510000046611_0_Linker_0_1 (967, 1210)

PLSQQNIGFRSALKRADAISSIGTSGLTDMKKLAKWAAESKLDPN-DPNNAPLM
QLISVATSGESYVPSFFRLEQLQQEFNFTSEEELNRSKRFRLLCLRSQEVPEFRNYKQIP
VYDREIMEKVFQDYEKRLRDRNVIETKDHLDAHRATVAKYLQQVRESVVNRFLTAKHHFL
LTDLVVEEEVPNISSEGSGILGL-SLFKLAEQKRPLRPRR-----KGRKKVTAQN-----
--LSDGDIK

PF00168 // ENSGT00510000046611_0_Domain_1 (1210, 1375)

LLVNIIRAYDIPVRKPAVSKFQQQSRSSRTFSEKQTAAPNMHSPVHSTDYP
LGQVLVRPFVEVSFQRTICHTTTAEGPNPSWNEELELPF---RAPNGDYSTASLQSVKDD
VYINIFDEVLYDILEDDRERGSG-MHTRIERHWLGCVKIPFSTIYFQARIDGTFKIDIPP
VLLGYSKERNIIMERAFDSARSLSEGSYITLFITIEPQLVPGEPMREKMSD----MLK-K
FDSQEDEKLLQAAEKFQAECASRFPQRQYLTTVIDMSGKTVFVTRFLKPLNPPQELLSVH
PNDPQATAELVARYVSLIPFLPDTVSFAGICDLWSTSD---QFLDLLAGDEEEHAVLLCN
YFLSLGKKAWLVMGNAIPEGPTAYVLTWEKNYYLIWNPCSGHCYGQFDTFCPLKSVGCLI
GTDNIWFNIQHHDSPLRINFDVTKPKLWKSFFSRS-LPYPGLSSVQPEELIYQHTDKTAA
AELQD--RIEKILKEKIMDWRPRHLTRWNRYCTSTLRHFLPLLERSQGEDIEDDHRAELL
RQLGDYRFSGFPLHMPYSEVKPLIEAVYSTGVHNIDVPNVEFALAVYIHPYPKNVLSVWI
YVASLVRNR

-----------MNPEEEKANIISEDFTGDGVD----TEAGRQK-------KNLKVQKKQ-
-KKKRPPTT-PPEEMVSDKFQDGGQQ------E--------MVEEEPETNLLSLPARRGP
R----------SLPPIPSAS-RTGFVEFSMRERMREKLQAARSKAESALLRDVPTPRPRR
LRSP-RERETETE--FGTEPSTEVQGTQQED-DTRSYSRIKLRDSVQKIKSKPQPPPGFP
SAEEAYNFFTFNFDPEPEEPEEKTPV---KGGDGAHQEEQEG--E-EGTHTQERE---KK
MEEEELLDGKDAEDFLLGLDPTAHDFVAVRAAEYKSAHLQLQKEKEILFTPSRLT----V
PTYKKLPENI-QPR-FLEDEGLYTG-ARPEVARTNENIMENRLLIQEPERKWFGDDGRIL
ALPSPIKPFPSRPSLSTQERSPKAELETLYKKAEKYVHS-RQHMIASGEPP--GNFQLDI
-DISGLIF-THHPCF-SREHVLASK----LAQLYDQFLA---------------------
----------RQQRNKTKFLTDKLQALRRAVETSLNPEKPHQSLDTTQKTINEYKSEIRQ
TRKLRDAEQEKDRTLLKTIIKVWK-EMKSLREFQRFTNTPLKLVLRKERVDQKLDE----
----------EVYEAEIQAEI-RELLEEHMEEYALKM-EEYRASRQHWKAWRKAQKAKKK
KK---KQTAEEHPE---E-EEAEEPFPEEEVKKPIPPEPTDPADIEQQVRERVAHSRRR

PF15625 // ENSGT00510000046611_0_Domain_0 (780, 967)

P
G-EPALIPELSLAGNVTPNDQ-CPRVEVSRREDVRRRSVYLKVVFNNKEVSRTVSRPLGA
DFRVHFGQ---IFNLQIFNWPESLMLQVYE-TIGHSGATLLA-EVFLPIPETTLVTGRAP
IE-EVEFSSNQHVTLDHEGVGSGVPFSFEADGSNQLTLMT-----SGKVSHSVAWAVGEN
GIPLIP

ENSGT00510000046611_0_Linker_0_1 (967, 1210)

PLSQQNIGFRSCLRNSVFISHLG-SGLADTKLYVHWPGESSLQLH-DPKHTYFI
FLGSVATSGESYVPDFFRLEQLQQEFNFVSEEELNRSKRFRLLQLRNQEVPEFRNYKQIP
VYDREIMEKVFQDYEKRLRDRNVIETKDHLDTHRATVAKYLQQVRESVVNRFLTAKHHFL
LTDLVVEEEVPNISSEGSGILGL-SLFKLAEQKRPLRPRR-----KGRKKVTAQN-----
--LSDGDIK

PF00168 // ENSGT00510000046611_0_Domain_1 (1210, 1375)

LLVNIIRAYDIPVRKPVVSKFQQPSRSSRTFSEKQTASPSTHSPLHNDDYP
LSQVLVRPFVEVSFQRTICHTTTAEGPNPSWNEELELPF---RAPNGDYSTASLQSVKDD
VYINIFDEVLYDILEDDRERGSG-IHTRIERHWLGCVKIPFSTIYFQARIDGTFKIDIPP
VLLGYSKERNIIMERAFDSARSLSEGSYITLFITIEPQLVPGEPIREKMSG----MLK-K
FDTQEDEKLLQATEKFQAECALKFPQRQCLTTVTDMNGKTVFITRYLKPLNPPQELLNVY
PNNPQATAELVARYVSLIPFLPDSVSFAGVCDLWSTSD---QFLDLLAGDEEEHAVLLCN
YFLFLGKKAWLVMGNAIPEGPTAYVLTWEKNYYLIWNPCSGHCYGQFDAFCPLKSVGCLI
GPDNIWFNIQHHDSPLRINFDVTKPKLWKSFFSRS-LPYPGLSSVQPEELIYQHTDKATA
AELQD--RIEKILKEKIMDWRPRHLTRWNRYCTSTLRHFLPLLERSQGEDIEDDHRAELL
KQLGDYRFSGFPLHMPYSEVKPLIEAVYSTGVHNIDLPNVEFALAVYIHPYPKNVLSVWI
YVASLVRNR

---------------------------------------------------------QT-
-RLSCPPVHS--SIFQSGFPPLSLSQE--------------------------PQTHLHQ
D----------SLPPIPSAS-RTGFAEFSMRERMREKLQAARRVA-----ARNPPPRPRR
LRSPG-EKEVETE--FGTEPGGETQRAQPED-DSQGHSRVKFHDSVRKIKSKPTVPPGFP
SAEEAYNFFTFNFDPEPEDSEEKP---RAKNRDGTNQEEKEG--EEEEPPVQEG---VNQ
TDEEELLEGKDAEDLLLGLDQAAEDFVAVRPADYESIHVQLQMEKELLFIPSRLT----V
PTYKKLPENV-QPR-FLEDEGLYIG-VRPEVPRTNQNIMENRLLTQDPGRRWFGDDGRIL
ALPNPIKPFPSRPPVSPREQDLKAELETLYKKAVKYVHR-SQHMIGAGDLP--GNFQLDI
-DISGLIF-THHPCF-SREHVLAAK----LAQLYDQYLA---------------------
----------RRQRNKAQFLTDKLQALRNAVHMGLHPAKAPKSLETTSKAINEYKSEIRQ
TRKLRDAEQEKDRALLKTIIKVWK-EMKSLREFQRFTNTPLKLVLRKEKVDQRAED----
----------EAYEAEIQAEI-SELLEEHAEEYERKM-EEYRAAQQQWKAWKKAQRAKKK
KKK---QAAEEHA-----DEEMEEPDPGEEPVKPIPPEPMDRAVLEQQVRERAAQSRRR

PF15625 // ENSGT00510000046611_0_Domain_0 (780, 967)

P
G-EPTLVPELSLAGSVTPNDQ-CPRVEVLRREDVRRRSVHLKVIFNNKEVSRTD------
NFRVHFGQ---IFNLQIFNWPESLTLQVYE-TIGHSGTSLLA-EVFLPIPETTVVTGRAP
VE-EVEFSSNQHVTLDHEGVGSGVPFSFEADGSNQLILMT-----SGKVANSVAWAIGEN
GIPLIP

ENSGT00510000046611_0_Linker_0_1 (967, 1210)

PLSQQNIGFRSALKRADAISSIGTSGLTDMKKLAKWAAESKLDPN-DPSNGPLM
QLISVATSGESYVPDFFRLEQLQQEFNFVSDEELNRSKRFRLLRLRSQEVPEFRNYKQIP
IYDREIMEKVFQDYEKRLRDRNVIETKDHIDTHRAIVAKYLQQVRESVINRFLIAKHHFL
LSDLIVEEEVPTCSV-IISILGL-SLFKLAEQKRPLRPRR-----KGRKKVTAQN-----
--LSDGDIK

PF00168 // ENSGT00510000046611_0_Domain_1 (1210, 1375)

LLVNIIRAYDIPVRKPTTSKFQQPSRSSRTFGEKHAASPTTHSPTHSADYP
LGQVLVRPFVEVSFQRTICHTTTAEGPNPSWNEELELPF---RAPNGDYSTTSLQSVKDD
VFINIFDEVLYDVLEDDRERGSG-IHTRIERHWLGCVKIPFSTIYFQARIDGTFKIDIPP
VLLGYSKERSVTADRGFDPVRSLSAGSYLTLFITLEPQLVPGESVREKV----------L
FDSQEDEKLLQAAEKFQAECALKFPNRQCLTTVIDISGKTVFITRYLKPLNPPQELLGAY
PNNPQATAELVARYVSLIPFLPDTVSFAGICDLWSTSD---QFLDLLAGDEEEHAVLLCN
YFLSLGKKAWLVMGNAIPEGPTAYVLTQEQSHYLIWNPCSGHFYGQFDTFCPLKSVGCLI
GPDNIWFNIQRYDSPLRINFDVTKPKLWKSFFSRS-LPYPGLSSVQPEELIYQRTDKVAA
AELQD--RIEKILKEKIMDWRPRHLTRWNRYCTSTLRHFLPLLERNQGEDVEDDHRAELL
RQLGDYRFSGFPLHMPYSEVKPLIEAVYSTGVHNIDAPNVEFALAVYIHPYPKNVLSVWI
YVASLIRNR

-----------MNPREEKVKIITEEFIENDED----ADMGRQN-------KNSKVRRQP-
-RKKQPPTA-VPKEMVSEKSHLGNPQ------E--------PVQEEPKTHLLSMTVRRGP
R----------SLPPIPSTS-RTGFAEFSMRGRMREKLQAARSKAESALLQEIPTPRPRR
LRSPS-KKELETE--FGTEPGKEVERTQQEI-DSQSYSRVKFRDSARKIKPKPRVPPGFP
SAEEAYNFFTFNFDPEPEGSEEKP---KARHRAGTNQEEEEE--EEEEPPAQGGG---KE
MDEEELLNGDDAEDFLLGLDHVADDFVAVRPADYESIHDRLQMEREMLFIPSRQT----V
PTYKKLPENV-QPR-FLEDEGLYTG-VRPEMARTNQNIMENRLLMQDPERRWFGDDGRIL
ALPNPIKPFPSRPPVLTQEQSIKAELETLYKKAVKYVHS-SQHVIRSGDPP--GNFQLDI
-DISGLIF-THHPCF-SREHVLAAK----LAQLYDQYLA---------------------
----------RHQRNKAKFLTDKLQALRNAVQTGLDPEKPHQSLDTIQKTINEYKSEIRQ
TRKFRDAEQEKDRTLLKTIIKVWK-EMKSLREFQRFTNTPLKLVLRKEKADQKADE----
----------EAYEAEIQAEI-SELLEEHKEEYAQKM-EEYRTSLQQWKAWRKAQRAKKK
KR---KQAAEEHP-----GDEIAEPYPEEDLVKPSPPEPTDRAVIEQEVRERAAQSRRRP
W-

PF15625 // ENSGT00510000046611_0_Domain_0 (783, 967)

EPTLVPELSLAGSVTPNDQ-CPRAEVSRREDVKKRSVYLKVLFNNKEVSRTVSRPLGA
DFRVHFGQ---IFNLQIVNWPESLTLQVYE-TIGHSSPTLLA-EVFLPIPETTVVTGRAP
TE-EVEFSSNQHVTLDHEGVGSGVPFSFEADGSNQLTLMT-----SGKVSHSVAWAIGEN
GIPLIP

ENSGT00510000046611_0_Linker_0_1 (967, 1210)

PLSQQNIGFRSALKKADAISSIGTSGLTDMKKLAKWAAESKLDPN-DPNNAPLM
QLISVATSGESYVPDFFRLEQLQQEFNFVSDQELNRSKRFRLLHLRSQEVPEFRNYKQVP
VYDREIMEKVFQDYEKRLRDRNVIETKEHIDTHRAIVAKYLQQVRESVINRFLIAKQYFL
LADMIVEEEVPNIS-----ILGL-SLFKLAEQKRPLRPRR-----KGRKKVTAQN-----
--LSDGDIK

PF00168 // ENSGT00510000046611_0_Domain_1 (1210, 1375)

LLVNIVRAYDIPVRKPAVSKFQQPSRSSRMFSEKHAASPSTYSPTHNADYP
LSQVLVRPFVEVSFQRTVCHTTTAEGPNPSWNEELELPF---RAPNGDYSTASLQSVKDV
VFINIFDEVLHDVLEDDRERGSG-IHTRIERHWLGCVKIPFSTIYFQARIDGTFKIDIPP
VLLGYSKERNMILEWGFDSVRSLSEGSYITLFITIEPQLVPGESIREKMSN----MLK-K
FESQEDEKLLQATEKFQAECALKFPNRQCLTTVIDISGKTVFITRYLKPLNPPQELLNVY
PNNLQATAELVARYVSLIPFLPDTVSFGGICDLWSTSD---QFLDLLAGDEEEHAVLLCN
YFLSLGKKAWLLMGNAIPEGPTAYVLTWEQGRYLIWNPCSGHFYGQFDTFCPLKNVGCLI
GPDNIWFNIQRYDSPLRINFDVTRPKLWKSFFSRS-LPYPGLSSVQPEELIYQHSDKAAA
AELQD--RIEKILKEKIMDWRPRHLTRWNRYCTSTLRHFLPLLEKSQGEDVEDDHRAELL
KQLGDYRFSGFPLHMPYSEVKPLIDAVYSTGVHNIDVPNVEFALAVYIHPYPRNVLSVWI
YVASLIRNR

-----------MNPREEKVKIITEEFTEND----EEADVGRWKKN-------SKAERHR-
-KKKQPPTA-GPGEMVSEKAHGSSQQEP--------------GQEESQTRLVSVPARRGP
R----------SLPPIPSTS-RTGFAEFSMRERMREKLQAARSKAESALLQEIPTPRPRR
LRSPR-EKETETA--FGTEPGKEIQATHQEE-DSQSYSRVKFHDAVRKIKSKPQAPPGYP
SAEEAYNFFTFNFDPEPEEPEVKA---KVRARDGTNQKEEEEEGEEEESPAG----GVNK
TDEEELLSGKDAEDLLLGLDPAADDSVAVRPAEYESIHTWLEKEKEILFIPSRQA----V
PICEKLPENV-QPR-FPEDEGLYTG-ARPEVTRANQNVAESRLLRQESGRKWFGDDGRIL
ALPSPIRPFPSRPPRLAQEPSAKAGLETLYRKAVKYVHR-TQHMIGSGDPP--GNFQLDI
-DISGLIF-THHPCF-SREHVLAAK----LAQLYDQYLA---------------------
----------RHRRNKAKFLTDKLQALRNAVQTGLHPEKPHQSLDATQKTVNEYKSEIRE
TRKMRNAEQEKDRTLLKTIIKVWK-EIKSLREFQRFTNTSLRLVLRKEKVDQKADE----
----------EAYEAEIQAEI-SELMEEHTEEYEQKM-EAYRASYQQWRAWKKAQKVKKK
KKKQ----AEEHPE----GQAEEESYPGEEPAKPVPPELPDQVALEQQVRERAAHSRRR

PF15625 // ENSGT00510000046611_0_Domain_0 (780, 967)

P
S-EPVLLPELSLAGSVTPNDQ-CPRVEVLRREDVKRRSVYLKVLFNSKEVSRTVSRQLGA
DFRVHFGQ---IFNLQIFNWPESLTLQVYE-TVGHSSTTLLA-EVFLPIPETTVVTGRAP
TE-EVEFSSNQHVTLDHEGVGSGVPFSFEADGSNQLTLMT-----SGKVSHSVAWAVGDN
GVPLIP

ENSGT00510000046611_0_Linker_0_1 (967, 1211)

PVSQQNAGFRSALKRADAISSIGTSGLTDMKKLAKWVAESKLDPN-DPNNAPLM
QLISVATSGESYVPDFFRLEQLQQEFNFVSDEELNRSKRFRLLRLRSQEVPEFRNYKQIP
AYDREIMERVFQDYEKRLRDKSVIETKDHMDTHRAIVAKYLQQVRESVVNRFLIAKHHFL
LADLVVEEEVPNISSEGSGSLGL-SLFKLAEQKRPLRPRR-----RGRKKVTAQN-----
--LSDGDIKL

PF00168 // ENSGT00510000046611_0_Domain_1 (1211, 1374)

LVNICRAYDIPVRKPSASKFQQPSRSSRTFSEKHAASPSAHSPNQSPDNP
LGQVLVRPFVEVSFQRTICHTTTAEGPNPSWNEELEFPF---RAPNGDYSSASLQSVKDD
VFINIFDEVLCDVLEDDRERGSG-IHTRIERHWLGCVKIPFSTIYFQGRIDGTFKIDTPP
VLLGYSKERNMLIERGFDSVRSLSEGSYITLFITIEPQLVPGESIQEKMSD----MLK-K
FDSQEDEKLLQATEKFQVECALKFPSRQCLTTVIDISGKTVFITRYLKPLNPPQELLNAY
PSNPQATAELVARYVSLIPFLPDTVSFAGICDLWSTSD---QFLDLLAGDEEEHAVLLCN
FFLFLGKKAWVVMGNAIPEGPTAYVLTWEQNHYLIWNPCSGHFYGQFDTFCPLKSVGCLI
GPDNIWFNIQQYDSPLRINFDVTKPKLWKPFFSRS-LPYPGLSSVQPEELIYQHTDKTAA
AELQD--RIEKMLKEKIMDWRPRHLTRWNRHCISTLRHFLPLLERSQGEGVDDDHRAELL
KQLGDYRFSGFPLHMPYSEVKPLIEAVYSTGVHNIDVPNVEFALAVYIHPYPKNVLSVWI
YVASLIRNR

--------------------VLTKEFTGDDVD----AEVGRRK-------KNSKVQRKQ-
-KKKKPPTT-PPEKMVSDKFQDGGQP------E--------MVEEEPETKLLSLTARRGA
R----------SLPPIPSAS-RTGFAEFSMRERMREKLQAARSKAESALLRDAPTPRPRR
LQSPS-ERETETE--FGTEPSKEVGGTQQED-NTQSHSRFKLHDSARKIKSKPQPPPGFP
SAEEAYNFFTFNFDPEP---EGRTQV---KGGDKAHQKDQEG--E-EGTHAQERT---KK
MEEEELLNGKDAEDFLLGLASTAHDFVSVRAAEYESVHIRLEKEKEILFTPSRLT----V
PTYKKLPENV-QPR-FLEDEGLYIG-ARPEVARTNENIMENRLLIQEPGRKWFGDDGRIL
ALPSPIKPFPSRPSLATQEQSTKAELETLYKKAVKYVHS-RQRMIGSGDPP--GNFQLDI
-DISGLIF-SHHPCF-SREHVLASK----LAQLYDQYLA---------------------
----------RQQRNKTQFLTDKLQALRKAIQTGLNPEKPHQSLDTTQKTINEYKSEIRQ
TRKLRDAEQEKDRTLLKTIIKVWK-EMKSLREFQRFTNTPLKLVLRKEKVDQKADE----
----------DEYEAEIQAEI-HELLEEHMEEYTRKM-EEYRALHQQWKAWRKAQRAKKK
KK---KQTAEEHPE---EEEEAEEPFP-EEIKKPIPPELTDPAVIEQQVRERVAHSRRR

PF15625 // ENSGT00510000046611_0_Domain_0 (780, 967)

P
G-EPTLVPELSLAGNVTPNDQ-CPRVEVLRREDVRRRSVYLKVVFNSKEVSRTVSRPLGA
DFRVHFGQ---IFNLQIFNWPESLMLQVYE-TIGHSGTILLA-EVFLPIPETTIVTGRAP
IE-EVEFSSNQHVTLDHEGVGSGVPFSFEADGSNQLTLMT-----SGKVSHSVAWAVGEN
GIPLIP

ENSGT00510000046611_0_Linker_0_1 (967, 1210)

PLSQQNIGFRSVLKRADAISSIGTSGLTDIKKLAKWAAESKLDPN-DPNNAPLM
QLISVATSGESYVPDFFRLEQLQQEFNFVSEEELNRSKRFRLLRLRSEEVPEFRNYKQIP
VYDREIMEKVFQDYEKRLRDRNVIETKDHLDAHRATVAKYLQQVRESVVNRFLIAKHHFL
LTDLVVEEEVPNISSEGSGILGL-SLFKLAEQKRPLRPRR-----KGRKKVTAQN-----
--LCDGDIK

PF00168 // ENSGT00510000046611_0_Domain_1 (1210, 1375)

LLVNIIRAYDIPVRKPIASKFQQTSRSSRTFSEKQTASPNTHSPVHSTDYP
LDQVLVRPFVEVSFQRTICHTTTAEGPNPSWNEELELPF---RAPNGDYSTASLQAVKDD
VYINIFDEVLHDILEDDRERGSG-IHTRIERHWLGCVKIPFSTIYFQARIDGTFKIDIPP
VLLGYSKERNITMERTFDSARSLSEGSYITLFITIEPQLVPGEPIREKMSD----MLK-K
FDSQEDEKLLQATEKFQAECALRFPQRQCLTTVIDMRGKTVFITRFLKPLNPPQELLNVY
PNNPQATAELVARYVSLIPFLPDTVSFAGICDLWSTSD---QFLDLLAGDEEEHAVLLCN
YFLSLGKKAWLMMGNAIPEGPTAYVLTWEKNYYLIWNPCSGHCYGQFDTFCPLKSVGCLI
GPDNIWFNIQHHDSPLRINFDVTKPKLWKSFFSRS-LPYPGLSSVQPEELIYQRTDKVAA
AELQD--RIEKILKDKIMDWRPRHLTRWNRYCTSTLRHFLPLLERSQGEDIEDDHRAELL
KQLGDYRFSGFPLHMPYSEVKPLIEAVYSTGVHNIDVPNVEFALAVYIHPYPKNVLSVWI
YVASLVRNR

-----------MNPREEKVKIITEEFIENDED----ADMGRQN-------KNSKVRRQP-
-RKKQPPTA-VPKEMVSEKSHLGNPQ------E--------PVQEEPKTRLLSMTVRRGP
R----------SLPPIPSTS-RTGFAEFSMRGRMREKLQAARSKAESALLQEIPTPRPRR
LRSPS-KKELETE--FGTEPGKEVERTQQEV-DSQSYSRVKFHDSARKIKPKPQVPPGFP
SAEEAYNFFTFNFDPEPEGSEEKP---KARHRAGTNQEEEEG--EEEEPPAQGGG---KE
MDEEELLNGDDAEDLLLGLDHVADDFVAVRPADYESIHDRLQMEREMLFIPSRQT----V
PTYKKLPENV-QPR-FLEDEGLYTG-VRPEVARTNQNIMENRLLMQDPERRWFGDDGRIL
ALPNPIKPFPSRPPVLTQEQSIKAELETLYKKAVKYVHS-SQHVIRSGDPP--GNFQLDI
-DISGLIF-THHPCF-SREHVLAAK----LAQLYDQYLA---------------------
----------RHQRNKAKFLTDKLQALRNAVQTGLDPEKPHQSLDTIQKTINEYKSEIRQ
TRKFRDAEQEKDRTLLKTIIKVWK-EMKSLREFQRFTNTPLKLVLRKEKADQKADE----
----------EAYEAEIQAEI-SELLEEHTEEYAQKM-EEYRTSLHQWKARRKAQRAKKK
KR---KQAAEEHP-----GDEIAEPYPEEDLVKPSPPEPTDRAVIEQEVRERAAQSRRRP
W-

PF15625 // ENSGT00510000046611_0_Domain_0 (783, 967)

EPTLVPELSLAGSVTPNDQ-CPRAEVWRREDVKKRSVYLKVLFNNKEVSRTVSRPLGA
DFRVHFGQ---IFNLQIVNWPESLTLQVYE-TIGHSNPTLLA-EVFLPIPETTVVTGRAP
TE-EVEFSSNQHVTLDHEGVGSGVPFSFEADGSNQLTLMT-----SGKVSHSVAWAIGEN
GIPLIP

ENSGT00510000046611_0_Linker_0_1 (967, 1210)

PLSQQNIGFRSALKKADAISSIGTSGLTDMKKLAKWAAESKLDPN-DPNNAPLM
QLISVATSGESYVPDFFRLEQLQQEFNFVSDQELNRSKRFRLLHLRSQEVPEFRNYKQVP
VYDREIMEKVFQDYEKRLRDRNVIETKEHIDTHRAIVAKYLQQVRESVINRFLIAKQYFL
LADMIVEEEVPNIS-----ILGL-SLFKLAEQKRPLRPRR-----KGRKKVTAQN-----
--LSDGDIK

PF00168 // ENSGT00510000046611_0_Domain_1 (1210, 1375)

LLVNIVRAYDIPVRKPAVSKFQQLSRSSRMFSEKHAASPSTYSPTHNADYP
LGQVLVRPFVEVSFQRTVCHTTTAEGPNPSWNEELELPF---RAPNGDYSTASLQSVKDV
VFINIFDEVLHEVLEDDRERGSG-IHTRIERHWLGCVKIPFSTIYFQARIDGTFKIDIPP
VLLGYSKEQNMILERGFDSVRSLSEGSYITLFITIEPQLVPGESIRE------------K
FESQEDEKLLQATEKFQAECALKFPNRQCLTTVIDISGKTVFITRYLKPLNPPQELLNVY
PNNLQATAELVARYVSLIPFLPDTVSFGGICDLWSTSD---QFLDLLAGDEEEHAVLLCN
YFLSLGKKAWLLMGNAIPEGPTAYVLTWEQGRYLIWNPCSGHFYGQFDTFCPLKNVGCLI
GPDNIWFNIQRYDSPLRINFDVTRPKLWKSFFSRS-LPYPGLSSVQPEELIYQRSDKAAA
AELQD--RIEKILKEKIMDWRPRHLTRWNRYCTSTLRHFLPLLEKSQGEDVEDDHRAELL
KQLGDYRFSGFPLHMPYSEVKPLIDAVYSTGVHNIDVPNVEFALAVYIHPYPKNVLSVWI
YVASLIRNR

----------------------------------------------------ARSIPCK-
-VNLLQLQTAGPEEMVSEKPRLGSQQEPVQ------------EDPHPDTRALSMPARRGP
R----------NLPPIPSAS-RTGFAEFFMRGRMREKLQAARSKAENALLQDIPTPRPRR
LRSPS-EKDSETD--FGTEPDRAVQRTQRED-DSQSYSRVKFRDSVRKIKSKPQVPPGFP
SAEEAYNFFTFNFDPEPEESEEKP---KAKNKDGTNQMEEEG--EEEEPPVPER---VNK
PDEEEMLNGKDAEDFLLGVEHAAGEFVAVRPADYESVHVRLQKEREILFVPSRLT----V
PTCKKLPENV-QPR-FLEDEGLYIG-TRPEVPRTAQNIVENRLLEQESGRKWFGDDGRIL
ALPNPIKPFPSRPPVLTQEQDVKAELETLYKKAVRYVHR-SPHMIGSGDSP--GNFQLDI
-DISGLIF-THHPCF-SREHVLAAK----LAQLYDQYLA---------------------
----------RCQRSKAKFLTDKLQALRNAVQTGLDPAKTHKSVDITPKAIKEYKSEIRX
XXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXEKVDQKADK----
----------EAYEAEIQAEI-SELLEERSEEYERAM-ASYRAAYQHWRAWKKGHKARKK
KKK---QAVKEHL-----DEEMEEPYPREEPVKPVPPEPIDPAVMEQQVRERAAQG-RRP
G-EPTLVPELSLAGSVTPNDQ-CPRAEVLRREDVKKRSVYLKVIFNEKEVSRTNSRPLGA
DFRVHFGQ---IFNLQIVNWPESLTLQVYE-TVGHSGTTLLA-EVFLPIPETTVVSGRAP
IE-EVEFSSDQHVTLDHEGVGSGVPFSFEADGSNQLILMT-----SGKVSNSVAWAVGEN
GIPLIPPLSQQNTGFRSALKRADAISSIGTSGLMDMKKLAKWAAESKLDPN-DPNNAPLM
QLISVATSGESYVPDFFRLEQLQQEFNFVSDEELNRSKRFRLLRLRSQEVPEFRNYKQVP
AYDREIMEKVFQDYEKRLRDRNVIETKEHIDTHRATVAKYLQQVRESVINRFLIAKHHFL
LTDLIVEEEVPN-----ISILGL-SLFKLAEQKRPLRPRR-----KGRKKVTAQN-----
--LSDGDIK

PF00168 // ENSGT00510000046611_0_Domain_1 (1210, 1334)

LLVNIIRAYDIPVRRPTASRFQQPSRSSRTFSEKRAASPTTHSPTHSADYP
LGQVLVRPFVEVSFQRTICHTTTAEGPNPSWNEELELPF---RAPNGDYSTTSLQSVKDD
VFINIFDEVLYDVLEDNRERGSG-IHTRIERHWLGCVKIPFSTIYSQA------------
-----------------------------------------------------------R
FDSQEDEKLLQATEKFQAECALKFPSRQCLTTVIDMSGKTVFITRYLKPLNPPQELLSAY
PDNPQATAELLARYVALIPFLPDTVSFAGICDLWSTSD---QFLDLLAGDEEEHAVLLCN
YFLSLGKKAWLVMGTAIPEGPTAYVLTREQSHYLIWNPCSGHFYGQFDTFCPLKSVGCLI
GPDNXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXPEELIYQRTDKAAA
AELQD--RIEKILREKIMGWRPRHLTRWNRHCTATLRHFLPLLEESRGEDVEDGHRAGLL
KQLGDYRFSGFPLHMAYSELRPLVEAVYSTGVHNIDVPSVEFALAVYIHPYPKNVLSVWI
YVASLIRNR

-----------MNPKEEKVKIISEEFTGEDVD----AEVGRQK-------KNSKVQRQQ-
-RKKKPPAT-PPEEMVSNKFQDGGQQ------E--------MVEEEPETNLLSLTARRGP
R----------SLPPMPSAS-RTGFAEFSMRERMREKLQAARSKAESALLRDVPTPRPRR
LRSPS-ERETETE--FGTEPSKEVGGTQQED-DSQSHARFKLRGSAQKIKSKPQPPPGFP
SAEEAYNFFTFNFDPEPEESEGKAQV---KGGGRARQEDQEG--E-EEACAQERA---KK
TEEEELLDGKDAEDFLLGLDPAAHDFVSVRAAEYESAHVRLQKEKEILFTPSRLT----V
PTYKKLPENV-QPR-FLEDEGLYIG-ERPEVARTNENIMENRLLIQEPGRKWFGDDGRIL
ALPSPIKPFPSRPSLPTQEQSTKAELETLYKKAVKYVHS-RQHMIGSGDPP--GNFQLDI
-DISGLIF-SHHPCF-SREHVLASK----LAQLYDQYLA---------------------
----------RQQRNKTKFLTDKLQALRKAVQAGLNPEKAHQSLDTTQKTINEYKSEIRQ
TRKLRDAEQEKDRTLLKTIIKVWK-EMKSLREFQRFTNTPLKLVLRKEKVDQKVDE----
----------DVYEAEIQAEI-HELLEEHTEEYTKKM-EEYRTSYQQWKAWRKAQRAKKK
KK---KETAEEHPE---EEEGVEEPFPEEELTKPVPPELTDPAVIEQQVRERVAHSRRK

PF15625 // ENSGT00510000046611_0_Domain_0 (780, 967)

P
G-EPRLVPELSLAGNVTPNDQ-CPRAEVSRREDVRRRSVYLKVVFNSKEVSRTVSRPLGA
DFRVHFGQ---IFNLQIFNWPESLMLQVYE-TIGHSGTSLLA-EVFLPIPETTLVTGRAP
IE-EVEFSSSQHVTLDHEGVGSGVPFSFEADGSNQLTLMT-----SGKVSHSVAWAIGEN
GIPLIP

ENSGT00510000046611_0_Linker_0_1 (967, 1210)

PLSQQNIGFRSALKRADAISSIGTSGLTDMKKLAKWAAESKLDPN-DPNNGPLM
QLISVATSGESYVPDFFRLEQLQQEFNFVSEEELNRSKRFRLLRLRSQEVPEFRNYKQIP
VYDREIMEKVFQDYEKRLRDRNVIETKDHLDTHRATVAKYLQQVRESVVNRFLTAKHHFL
LTDLVVEEEVPNISSEGSGILGL-SLFKLAEQKRPLRPRR-----KGRKKVTAQN-----
--LSDGDIK

PF00168 // ENSGT00510000046611_0_Domain_1 (1210, 1375)

LLVNIIRAYDIPVRKPTVSKFQQPSRSSRTFSEKQTASPGTHSPVHSTDYP
LGQVLVRPFVEVSFQRTICHTTTAEGPNPSWNEELELPF---RAPNGDYSTASLQSVKDD
VYINIFDEVLYDILEDDRERGSG-IHTRIERHWLGCVKIPFSTIYFQARIDGTFKIDIPP
VLLGYSKERNIIMERAFDSARSLSEGSYITLFITIEPQLVPGEPIREKMSG----MLK-K
FDSQEDEKLLQATEKFQAECALRFPRRQCFPTVIDMSGKTVFVTRFLKPLNPPQELLSVY
PNDPQATAELVARYVSLIPFLPDTVSFAGICDLWSTSD---QFLDLLAGDEEEHAVLLCN
YFLSLGKKAWLVMGNAIPEGPTAYVLTLEKNYYLIWNPCSGHCYGQFDTFCPLKSVGCLI
GPDNIWFNIQHHDSPLRINFDVTKPKLWKSFFSRS-LPYPGLSSVQPEELIYQRTDKAAA
AELQD--RIEKILKEKIMDWRPRHLTRWNRHCTSTLRHFLPLLERSQGEDIEDDHRAELL
KQLGDYRFSGFPLHMPYSEVKPLIEAVYSTGVHNIDVPNVEFALAVYIHPYPKNVLSVWI
YVASLVRNR

------------------------------------------------------------
--------------MVSEKAPGGSQQKP--------------GQEEPETQLLSVPSRRGP
R----------SLPPIPSAS-RTGFAEFSMRERMREKLQAARSKAESALLQEIPTPRPRR
LRSPR-EKESETE--FRTEPGKEIQATQHEE-DSRSHSRVKFHDAVQKIKSKPQAPPGFP
SAEEAYNFFTFNFDPEPEEPEVKA---KVRARDGANQEEEEEEGVEDESPTG----GLNR
KDEEELLSGKDAEDFLLGLDPAADDFVAVRPAEYESIHTWLEKEKEVLFIPSRQA----V
PTYKKLPENV-QPR-FPEDEGLYTG-ARPQVTRSNQNVAESRLLRQEPGRKWFGDDGRIL
ALPSPIKPFPTRPPRLAQEPSAKEGLETLYKKAVKYVHR-TQHMIGSGDPP--GYFQLDI
-DISGLIF-THHPCF-SREHVLAAK----LAQLYDQYLA---------------------
----------RHQRNKAKFLTDKLQALRNAVQTGLHPEKPHQSLDATQKTISEYKSEIRE
TRKLRDAEQEKDRTLLKTIIKVWK-EMKSLREFQRFTNTSLRLILRKGKVDQKADE----
----------EAYEAEIQAEV-RELLAEHTEEYGQKM-EAYRASYQHWKARGKAQKARKK
KKKQ----AEERPE----GEDDEAPDPGEESVKPVPPELPDRVALEQQVRERAAHSRRQ

PF15625 // ENSGT00510000046611_0_Domain_0 (780, 967)

P
S-EPVLLPELSLAGSVTPSDQ-CPRAEVSRREDVKRRSVYIKVLFNGKEVSRTVSRQLGA
DFRAHFGQ---IFNLQIFNWPESLTLQVYE-TVGHSSTTLLA-EVFLPIPETTVVTGRAT
IE-EVEFSSNQRVTLDHEGVGSGVPFSFEADGSNQMILMT-----SGKVSHSVAWAVGDN
GVPLIP

ENSGT00510000046611_0_Linker_0_1 (967, 1242)

PPSQQNAGFRSALKRADAISSIGTSGLTDMKKLAKWAAESKLDPN-DPNNAPLM
QLISVATSGESYVPDFFRLEQLQQEFNFVSDEELNRSKRFRLLRLRNQEVPEFRNYKQIP
AYDREIMERVFQDYEKRLRDKSVVETKDHIDAHRAIVAKYLQQVRESVVNRFLIAKHHFL
LADLVVEEEVPNISSEGSGILGL-SLFKLAEQKRPLRPRR-----KGRKKVTAQN-----
--LSDGDIKLLVNICRAYDIPVRRPTASKFQQPSRSSRTFS

PF00168 // ENSGT00510000046611_0_Domain_1 (1242, 1375)

EKRAASPSAHSPTHSPDSP
LGQVLVRPFVEVSFQRTICHTSTAEGPNPSWNEELAFPF---RAPNGDYSTASLQSVKDD
VFINIFDEVLYDVLEDDRERGSG-IHTRIERHWLGCVKIPFSTIYFQARIDGTFKIDIPP
VLLGYSKERNMIIERGFDSVRSVSKGSYITLFISVEPQLVPGEPIRE------------K
FDSQEDEKLLHATEKFQAECALKFPSRQCLTTVTDLSGKTVFITRYLKPLNPPQELLNAC
PSNPQATAELVARYVALIPFLPDTVSFAGICDLWSTSD---QFLDLLAGDEEEHAVLLCN
YFLFLGKKAWLVMGNAIPEGPTAYVLTWEQNHYLIWNPCSGHFYGQFDTFCPLKSVSCLI
GPDNIWFNIQQYDSPLRINFDVTKPKLWKSFFSRS-LPYPGLSSVQPEELIYQRTDKTAA
AELQD--RIEKMLKDKIMDWRPRHLTRWNRHCTSTLRHFLPLLERSHGEGVEDEHRAELL
KQLGDYRFSGFPLHMPYSEVNPLIEAVYSTGVHNIDVPNVEFALAVYVHPYPKNVLSVWI
YVASLIRNR

-----------MNTNDEKMKIISEDFTGDGVD----TEAGRRK-------KNSKVRRQQ-
-RKKKPPAS-PPEEMVSDKFQDGGQQ------E--------VVEEEPETNLLSLTARRGP
R----------SLPPIPSAS-RTGFAEFSMRERMREKLQAARSKAESALLRDVPTPRPRR
LRSPSREKETETE--FGTEPSTEVQDTQKED-DTKSYSRIKFRDSVRKIKSKPQLPPGFP
SAEEAYNFFTFNFDPEPEESEEKSPV---KGGERAHHEDQEG--E-EGTQAQERA---KK
TEEEELLNGKDAEDFLLGLDPTAHDFVAVRAAEYKSARIQLQKEKEILFTPSRLT----V
PTYKKLPENI-QPR-FLEDEGLYIG-ARPEVARTNENIMENRLLIQEPGSKWFGDDGRIL
ALPSPIKPFPSRPSLTTREQSPKAGLETLYKKAEKYVHS-RQHMIGSGDPP--GNFQLDI
-DISGLIF-THHPCF-SREHVLASK----LAQLYDQYLA---------------------
----------RQQRNKTKFLTDKLQALRKAVQTSLNPEKPHQSLDTTQKTINEYKSEIRQ
TRKLRDAEQEKDRTLLKTIIKVWK-EMKSLREFQRFTNTPLKLVLRKEKVDPKLDE----
----------DAYEAEIQAEI-HELLEEHMEEYATKM-EEYRTSHQQWKAWRKAQRAKKK
KK---KQTTEEHLE---E-EEAEESFPEEEVTKPIPPEPTDPAVIEQQVRERAAHSRRR

PF15625 // ENSGT00510000046611_0_Domain_0 (780, 967)

P
G-EPTLIPELSLAGNVTPNDQ-CPRVEVSRREDVRRRSVYLKVVFNSKEVSRTVSRPLGA
DFRVHFGQ---IFNLQIFNWPESLMLQVYE-TIGHSGTTLLA-EVFLPIPETTLVTGRAP
IE-EVEFSSNQHVTLDHEGVGSGVPFSFEADGSNQLTLMT-----SGKVSHSVAWAVGEN
GIPLIP

ENSGT00510000046611_0_Linker_0_1 (967, 1210)

PLSQQNIGFRSALRRADAISSIGTSGLTDMKKLAKWAAESKLDPN-DPNHAPLM
QLISVATSGESYVPDFFRLEQLQQEFNFVSEEELNRSKRFRLLHLRSQEVPEFRNYKQIP
AYDREIMEKVFQDYEKRLRDRNVIETKDHLDMHRATVAKYLQQVREAVVNRFLTAKHHFL
LTDLVVEEEVPNISSEGSGILGL-SLFKLAEQKRPLRPRR-----KGRKKVTAQN-----
--LSDGDIK

PF00168 // ENSGT00510000046611_0_Domain_1 (1210, 1375)

LLVNIIRAYDIPVRKPVVSKFQQPSRSSRTFSEKQTASPSTHSPLHNADYP
LGQVLVRPFVEVSFQRTICHTTTAEGPNPSWNEELELPF---RAPNGDYSTASLQSVKDD
VYINIFDEVLYDILEDDRERGSG-IHTRIERHWLGCVKIPFSTIYFQARIDGTFKIDIPP
VLLGYSKERNIIMERAFDSARSLSEGSYITLFITIEPQLVPGEPMREKMSD----MLK-K
FDTQEDEKLLQATEKFQAECALKFPQRQCLTTVTDMTGKTVFITRYLKPLNPPQELLHVY
PNNPQATAELVARYVSLIPFLPDSVSFAGVCDLWSTSD---QFLDLLAGDEEEHAVLLCN
YFLFLGKKAWLVMGSAIPEGPTAYVLTWEKNYYLIWNPCSGHCYGQFDAFCPLKSVGCLI
GPDNIWFNIQHHDSPLRINFDVTKPKLWKSFFSRS-LPYPGLSSVQPEELIYQHTDKAVA
AELQD--RIEKILKEKIMDWRPRHLTRWNRYCTSTLRHFLPLLERSQGEDIEDDHRAELL
KQLGDYRFSGFPLHMPYSEVKPLVEAVYSTGVHNIDLPNVEFALAVYIHPYPKNVLSVWI
YVASLVRNR

-----------MNPREEKVKIITEEFIENDED----ADMGRQK-------RNSKVRRQP-
-RKKQPPTA-LPKEMVSEESHFGNQP------E--------PVQEEPKTHLLSMTVRRGP
R----------SLPPIPSTS-RTGFAEFSMRGRMREKLQAARSKAESALLQEIPTPRPRR
LRSPS-KKELETE--FGTEPGKEVESTQQEI-DSRSYSRVKFRDSARKIKPKPQVPPGFP
SPEEAYNFFTFSFDPEPEESEEKP---KARHRAGTNQEEEEG--EEEEPPAGGRG---KE
MDEEELLNGDDAEDFLLGLDHMADDFVAVRPADYESIHDRLQMETEMFFIPSRQT----V
PTYKKLPENV-QPR-FLEDEGLYTG-VRPEVARTNQNIMENRLLMQDPERRWFGDDGRIL
ALPNPIKPFPSRRPVLTQEQSIKAELETLYKKAVKYVHS-SQHMIRSGDHP--GNFQLDI
-DISGLIF-THHPCF-SREHVLAAK----LAQLYDQYLA---------------------
----------RHQRNKAKFLTDKLQALRNAVQTGVDPEKPHSSLDTIQKTINEYKSEIRQ
TRKFRDAEQEKDRTLLKTIIKVWK-EMKSLREFQRFTNTPLKLVLRKEKVDQKADE----
----------EAYEAEIQAEI-SELLEEHTEEYAQKM-EEYRTSLHQWKAWRKAQRAKKK
KR---KQAAEDHP-----DDEIEEPHPEEDLVKPTPPEPTDRAVIEHEVRERAAQSRRRP
W-

PF15625 // ENSGT00510000046611_0_Domain_0 (783, 967)

EPTLVPELSLAGSVTPSDQ-CPRAEVSRREDVKKRSVYLKMLFNNKEVSRTVSRPLGA
DFRVHFGQ---IFNLQIVNWPESLTLQVYE-TIGHSSPTLLA-EVFLPIPETTVVTGRAP
IE-EVEFSSNQHVTLDHEGVGSGVPFSFEADGSNQLILMT-----SGKVSHSVAWAVGEN
GIPLIP

ENSGT00510000046611_0_Linker_0_1 (967, 1210)

PLSQQNIGFRSALKRADAISSIGTSGLTDMKKLAKWAAESKLDPN-DPNNAPLM
QLISVATSGESYVPDFFRLEQLQQEFNFVSDQELNRSKRFRLLHLRSQEVPEFRNYKQVP
VYDREIMEKVFQDYEKRLRDRSVIETKEHIDTHRAIVAKYLQQVRESVINRFLIAKQYFL
LADMIVEEEVPNIS-----ILGL-SLFKLAEQKRPLRPRR-----KGRKKVTAQN-----
--LSDGDIK

PF00168 // ENSGT00510000046611_0_Domain_1 (1210, 1375)

LLVNIVRAYDIPVRKPAMSKFQQPSKSSRMFTEKRAASPSTHSPTHNADYP
LGQVLVRPFVEVSFQRTVCHTTTAEGPNPSWNEELELPF---KAPNGDYSTASLQSVKDI
VFINIFDEVLHDVLEDDRERGSG-IHTRIERHWLGCVKIPFSTIYFQARIDGTFKIDIPP
VLLGYNKERNMILERGFDSVRSLSEGSYITLFITIEPQLVPGESIRE------------K
FESQEDEKLLQATEKFQAECALKFPNRQCLTTVIDISGKTVFITRYLKPLNPPQELLNVY
PNNLQATAELVARYVSLIPFLPDTVSFGGICDLWSTSD---QFLDLLAGDEEEHAVLLCN
YFLSLGKKAWLLMGNAIPEGPTAYVLTWEQGHYLIWNPCSGHFYGQFDTFCPLKNVGCLI
GPDNIWFNIQRYDSPLRINFDVTKPKLWKSFFSRS-LPYPGLSSVQPEELIYQRSDKAAA
AELQD--RIEKILKEKIMDWRPRHLTRWNRYCTSTLRHFLPLLEKSQGEDVEDDHRAELL
KQLGDYRFSGFPLHMPYSEVKPLIDAVYSTGVHNINVPNVEFALAVYIHPYPKNVLSVWI
YVASLIRNR

------------------------------------------------------------
------------------------------------------------------------
------------LPPIPSAF-RTGFAEFSMRERMREKLQAARSKAESALLQEIPTPRPRR
SRSPS-EKQVETE--FGTEXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXVPPGFP
SAEEAYNFFTFNFDPEPEESEEKP---KAKHRGGTNQEEKEG--EEEEPPVREGA---NK
TGEEELLEGKDAEDLLLGLDHADADFVAVRPADYEGVRVRLQMEKELLFTPSRLT----V
PTYKKLPENV-QPR-YLEDEGLYIG-ARPEVPRTNQNIMENRLLTQEPGRRWFGDDGRIL
ALPNPIRPFPSRPPVLTQEQDIKAELETLYTKAVKYIHR-SQHMIGSGDPP--GNFQLDI
-DISGLIF-THHPCF-SREHVLAAK----LAQLYDQYLA---------------------
----------RRQRNKAKFLTDKLQALRNAVQMGLNPAKSPKSLKTTPKAINEYKSEIRQ
TRRLRDAEQEKDRTLLKTIIKVWK-EMKSLREFQRFTNTPLKLVLRREKVDQKADE----
----------EAYEAEIQAEI-RELLEEHTEDYEQKM-EEYRTAHQQWKAWKKAQXXXXX
XXXXXXXXXXXXXX---XXXXXXXXXXXXXXXXXX----XXXXXXXXXXXXXXXXX-XXX
X-XXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXE-VSRLSRPLGA
DFGVHGQI-----NLQ-LVWPESLTQQVYE-TVGHSGATLLA-EVFLPIPETTVVTGRAP
IE-EVEFSSNQHVTPDHEGVGSGVPFSFEADGSNQLTLMT-----SGRVSNSVAWAIGEN
GIPLIPPLSQQNIGFRSALKRADAISSIGTSGLTDMKKLAKWAAESKLDPN-DPSNAPLM
QLISVATSGESYVPDFFRLEQLQQEFNFVSDEELNRSRRFRLLRLRSQEVPEFRNYKQIP
LYDREIMEKVFQDYEKRLRDRNVIETKDHIDINRATVAKYFQQVRDSVINRFLVAKHHFL
LSDLIVEEEVPNIS-----ILGL-SLFKLAEQKRPLRPRR-----KGRKKVTAQN-----
--LSDGDIK

PF00168 // ENSGT00510000046611_0_Domain_1 (1210, 1334)

LLVNIIRAYDIPVRKPTTSKFQQPSRSSRAFGEKHAASPTARSPTHSADYP
LGQVLVRPFVEVSFQRTICHTTTAEGPNPSWNEELELPF---RAPNGDYSTTSLQSVKDD
VFINIFDEVLQDVLEXXXXXXXX-XXXXXXXXXXXX------------------------
-------------------------------------------XXXXXXXX----XXXXX
FDSQEDEKLLQATEKFQAECALKFPNRQCLTTVIDISGKTVFITRYLKPLNPPQELLNAY
PNNPQATAELVARYVSLIPFLPDSVSFAGICDLWSTSD---XXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXGPTAYVLTREQSHYLIWNPCSGHFYGQFDTFCPLKSVGCLI
GPDNIWFNIQRYDSPLRINFDVTKPKLWKSFFSRS-LPYPGLSSVQPEELIYQRTDKVAA
AELQD--RIEKILKEKIMDWRPRRLTRWNRYCASTLRHFLPLLERSQGEGAEDDHRAELL
RQLGDYRFSGFPLHMPYSEVKPLIEAVYSTGVHSIDAPNAEFALAVYIHPYPKNVLSVWI
YVASLILIK

-----------MKSKEEKVKIITEEYIDDGED----AEEERQK-------KPSKVPRQK-
-RKKQLPAAG-REEMVSENSPVDDQQEPVQ------------EG--SDTHLLGVMSRRGP
R----------SLPPIPSAS-RTGFAEFSMRERMREKLQAARSKAESALLQEIPTPRPRR
LRSPT-EKESETE--FGTELDREVQRTQQEH-DSQGHSRVKFHDSVRKIKSKPLVPPGFP
SAEEAYNFFTFNFDPEPEEPEEKP---KAKNRHGANREEKEG--EEEEPPVQEG------
-DEEEWLDGRDAEDLLLGLDHAAEDFVAVRPADYESVHVRLQREKELLFVPSRRT----V
PTYKKLPENV-QPR-YLEDEGLYIG-ARPEVPRTNQNIMENRLLTQEPGRRWFGDDGRIL
ALPNPIKPVPSRPPMFTQAQDIKPELETLYKKAVKYIHR-SQHLIGSGDSP--GNFQLDI
-DISGLIF-THHPCF-SREHVLAAK----LAQLYDQYLA---------------------
----------RRQRNKAKFLTDKLHALRNAVQMGLNPAKTPKTLETTSKTINEYKSEIRE
TRKLRDAEQEKDRMLLKTIIKVWK-EMKSLREFQRFTNTPLKLVLRKEKVDQKADE----
----------EAYEAEIQAEI-NELLEEHTEEYEQKM-EVYRVMLQQWKAWKKAQRAKKK
KKKQ-EV-EEHPA-----DEEREEPGPGEEPEKPAPPEPVDRAVIEQQVRERAAQSRRR

PF15625 // ENSGT00510000046611_0_Domain_0 (780, 967)

P
G-EPTLVPELSLAGSVTPNDQ-CPRVEVLRREDVKRRSLFLKVTFNNKEVSRTESRPLGA
DFRVHFGQ---IFNLQIFNWPESLTLQVYE-TVGHSGTTLLA-EVFLPIPETTVVSGRAP
IE-EVEFSSNQHVTLDHEGVGSGVPFSFEADGGNQLILMT-----SGKVSNNVAWAIGEN
GIPLIP

ENSGT00510000046611_0_Linker_0_1 (967, 1210)

PLSQQNIGFRSALKRADAISSIGTSGLTDMKKLAKWAAESKLDPN-DPSNGPLM
QLISVATSGESYIPDFFRLEQLQQEFNFVSDEELNRSKRFRLLLLRSQEVPEFRHYKQIP
LYDREIMEKVFQDYEKRLRDRNVIETKDHIDSHRATVAKYLQQVRESVINRFLIAKHHFL
LSDLVVEEEVPNIS-----ILGL-SLFKLAEQKRPLRPRR-----KGRKKVTAQN-----
--LSDGDIK

PF00168 // ENSGT00510000046611_0_Domain_1 (1210, 1375)

LLVNIIRAYDIPVRKPTASKFHQTSRSSRTFTEKHAASPTTHSPAHSADYP
LGQALVRPFVEVSFQRTICHTTTAEGPNPSWNEELELPF---RAPNGDYSTTSLQSVKDD
VFINIFDEVLYDVLEDDRERGSG-IHTRIERHWLGCVKIPFSTIYFQARIDGTFKIDIPP
VLLGYSKERSVMMDRGFDSVRSLSEGSYITLFITLEPQLVPGESVRE------------K
FDSQEDEKLLQATEKFRAECALKFPNRQCLTTVVDVSGKTVFVTRYLKPLNPPQELLNAY
PNNLQATAELVARYVSLIPFLPDTVSFAGVCDLWSTSD---QFLDLLAGDEEEHAVLLCN
YFLSMGKKAWLVTGNAIPEGPTAYVLTQEQSHYLIWNPCSGHFYGQFDTFCPLKSVSCLI
GPDNIWFNIQQYDSPLRINFDVTKPKLWKSFFSRS-LPYPGLSSVQPEELIYQRTDQVAA
AELQD--RIEKILKEKIMDWRPRHLTRWNRYCTSTLRHFLPLLERNQ-EDVEDDHRAELL
KQLGDYRFSGFPLHMPYSEVKPLIEAVYSTGVHNIDAPNVEFALAVYVHPYPKNVLSVWI
YVASLIRNR

-----------MRHSEEKQRMVTQDYVDNEEAEVEQL-----K-------KKLRAQRHRR
KKAKLPPKIKSYRDTVIP-AHLTDHDEE-------------IQTEDPVED--LTATVRGQ
R----------SLPPLAASTPVPSAAEASMRERLRERLKAARSKAESTLQDESPVVSPQR
LPKSKH-ADSFRR--FNEEDSFQLDR--VREAETELTSRVRFREAVKTVQKKSQAQDGYP
SAEESYNFFTFDFETDMDNKKHDVPEK-----------EDVEEGESSIK-------PLEE
EDQEEAENGMVPEDDLFVIDQTLRDFIELLPAEYEGYRNQLQKELDCFFIPSIQP----V
PTSKKVPENM-QPR-FLEDEGLYTG-ERPKITQTNQNILENRILRQEESKKWFGDDGKIL
ALANPIKQSSTRPPIFSLHEGIDQALETIYVKAGPPKEE-NRYAVGS------GEYQLDI
-DISGIVF-THHPLF-SREHVLASK----LAQLYDQYLG---------------------
----------RKQKNLSGLLTDKLHALRNAVQNIYGIRAANSSRTFVEQSISEYKLEISG
SNAKRKGESGPWLTLLKQVTLVWQ-HLQSIAIHQSY--SPLYSTCTREDVNKKSDE----
----------EAHEAEIQAEI-QELIEEYMEDYEKDM-VQYKSDLQKWKSWRKAQKLKKK
KKKEG-------AD---EEEELGASHTGEELPKPVPPEIIDKKDVEQQVREKAAHIRRKP
G-EPILIPEMNLSGAVTPNEL-CPRVEVQRREDIQKHSLFIRILFNNKEVSRTIAKRLGS
DFRVHLGE---IFNLQIFNLPESIKLEIYE-TVRHGATTLLA-DAFIPIPETTVHTGRAP
VE-EIEFSSNQRVMHDHEGVGSDVPFSFEADGSNKMILMT-----SGKVSYAASWGVGDN
GVPLVPPILQYNTGIQRAFNNMDAVASIGASGLTDMKKLAKWAAESKLDPN-DPNNAALM
QLVMTASNGEASVPEFFRLEHLQKEFNFTSEEELRRSKRFRLLQLRNQEVAEFRNYKQIP
LKDREIPDKLFQDYEKKLREQDTITAESHLDKHRVLVAKYLQRVRESVINRFLVAKHHFI
LSDLVIEEDIPSL-----GILGM-SLFKLAEPKRPLKPRR-----KERKKVTAQN-----
--LSDGDIK

PF00168 // ENSGT00510000046611_0_Domain_1 (1210, 1327)

VLVNVIRAYDIPVRKQVTSKPAQQPRSARSFNEMFTSAASPQGQTPTPEST
VNQVLVRPFVEVSFQRTVCQTTTADGPNPNWNEELVLPF---RAPNSDYSTASLQSVKDD
VFINVFDEVSYDILEDDRERGHG-IHTRIERHWLGSVRIPFTTIYFQARIDGTFLIETPP
VLLGYSKQRSAGIEGGYDATRGLSQGSFLTLFITIEPQLVPGEPVREK-----------K
FESREDEKLLQAAEKYQSEGVQKYPNRQCLTTVTDINGTTVFVTRYIKPLNPPQELLDAH
PNNTQAASELVAHYVSLIPFLPDNVSFAGICNLWSTAD---QFLDLLAGDEEEHAVLLCN
YFLAMGKKAWLLIGNAVPEGPTTYVLTLEQNQYIIWNPSTGRFYGQYDTFCPLQSVGCLI
NADNIWFNTQQYDAPVSMTFDTSRTNMWKPFFSRS-YPHPGLSSVQPEELMYQRIDKAAA
AELQD--RIEKILKEKIMEWRPRHPTRWNRFCTSTLRHFLPLLELNRGRDVEEDHRAELQ
RQLGDYRFSGFPIHMAFSEVRPLIEAVYSTGVQNSEVPNVEFALAVYVHPYPKNIYSVWV
YVASLVRNR

------------------------------------------------------------
-----------------------------------------------MATAPAAAAPPAP
R----------SLPPVPSTS-RMGFSELSVRERMREKLKAARSKAEATLSQEDLGPRPRH
LKSIRE-RKAELRLDKG--SGDQLGE--LQRDESLLSSKIKFSDSVKKLKQKSQAQSDYP
SAEEAYNFFTLNFDPEPESIKAGA-----RKRSELNEEE--AE---EYVETHEEEQEEDE
TDEDAHL---VKDADLFIMGQTDEDFLVTKPAECERYSEQLQKEKEFLFIPSMQT----V
PTSQKMPENM-QPR-YLEDEGLYAE-ERPFVSPSNQNILENRILRQEKGKEWFGDDGRIL
ALPNPIKQSSTRPPVFSLEEGIAPELETIYRKAIRTTAA-NQYLIGPGDFQ--GPFQLDI
-DISGLIF-THHPCF-SREHVLAAK----LAQLYDQYLA---------------------
----------RKQKNLTELLTDKLRALRNAVQCSMDS--AAASGPTAQQSIPEYKIEIRQ
TRRLRDAEQEKDRMLLKSIIKVWK-QMKSLREFQKFTNTPMKLYLRKEEVDQRSDE----
----------KAYEAEIQAEI-NELQEEYMEEYEKKM-EEYKTELQEWKSWKKAQKSKKK
-KKKDLR------E---E-ESVEDYDVGEEPVKPVPPKMVDSLEIEQQVREKANNFRRK

PF15625 // ENSGT00510000046611_0_Domain_0 (780, 967)

P
G-EPALIPELVLSGSITPSEQ-CPRAEVLRREDVNKRSAFIKVFFNSKEVSRTVTRPLSS
DFRVHFGQ---IFNLQIFNWPESLKLQIYE-TTGMSSTTLLA-EVFIPVPETTVLTGSAP
ME-EIEFSSNQRVMLDHEGVGSDVSFSFEADGSNQMTLMT-----SGKVSNSVSWAVGEK
GIPLVP

ENSGT00510000046611_0_Linker_0_1 (967, 1210)

PVSQQNTGIPSALKNIDAIASIGTSGLTDMKKLAKWAAETRLDPN-DPNNAALM
QMIMVASSGEAHVPDFFRLEQLQQEFNFVSDEEFNRSKRFRLLQLRNEEVAEFRNYKQVP
LHEREISEKLFQEYEKRLHERDVIDSKHYLDARRAVVANYLQKVRESVINRFLIAKHHFL
LSDLVNEEEIPTLG-----ILGL-GLFKLAEPKRPLKPRR-----KERKKVTAQS-----
--LSDGDIK

PF00168 // ENSGT00510000046611_0_Domain_1 (1210, 1375)

LLVNIIRAYDIPVRKPVTSKLQQPSKSSRSFNEMFAASPSAQSPTNNVDWA
FDQVLVRPFVEVSFQRTVCRTTTAEGPNPNWNEELEFPF---RAPNGDYSTHSLQSVKDE
VFINVFDEVLHDVTEDDRDRGSG-IHTRIERRWLGCVKIPFTTIYFQARIDGTFKVNIPP
VLLGYSKEKNLGIERGYDSVRNLSEGSYITLFITIEPQLIPGESVREKMNE----MLK-K
FDTQEDEKLLQAAEKYEAECTSKFPSRQCLTTVIDLSGKTVFITRYIKPLNPPQELLDAL
PNSSQTTAELVARYVALIPFLPDSVSFAGICDLWCTSD---QFLDLLAGDEEEHAVLLCN
YFLGMGKKAWLIIGNAIPEGQTAYVLTLEQSQYVIWNPSTGCFYRQYDTFCPLQSVYCLI
SCDNIWFNIQQWDSPVRISFDISKPKLWKPFFSRS-LPYPGLCSVQPEELVYQHSDKAAA
VELQG--RIEKILKEKIMEWRPRHLTRWNRYCTSTLRNFLPLLEQNQGKDVEDDHQAELQ
KQLGDYRVSGFPIHMPFSEVRPLVEAVHSTGVHTIDVSNVEFALAVYVHPYPQNVLSTWI
YVASLVRNR

-----------MNPREEKVKIITEEFIENDED----ADMERQK-------KNPKVRRQP-
-RKKQPPTA-VRKEMVSEKSHLGNQQ------E--------PVQEEPKTCLLSMTARRGP
Q----------SLPPIPSTS-RTGFAEFSMRGRMREKLQAARSKAESALLQEIPTPWPRR
LRSPS-KKELETE--FGTEPGKEVESTQQEI-DSQSHSRVKFHDSARKIKPKPQVPPGFP
SAEEAYNFFTFNFDPEPEESEKKP---KARHREGTNLEQEEG--E-EEPPAHGGG---KE
TDEEELLNGDDAEDFLLGLDHMADDFVAVRPADYESIHDRLQMEREMLFIPSRQT----V
PTYKKLPENV-QPR-FLEDEGLYTG-VRPEVSRTNQNIMENRLLVQDPERRWFGDDGRIL
ALPNPIKPFPSRLPVETQELSIKAELETMYKKAVKYVHS-SQHVIRSGDPP--GNFQLDI
-DISGLLF-THHPCF-SREHVLAAK----LAQLYDQYLA---------------------
----------RHQRNKAKFLTEKLQALRNAVQTGLDPEKPHQSLDTIQKTINDYKSEIRQ
TRKLRDAEQEKDRTLLKTIIKVWK-EMKSLREFQRFTNTPLKLVLRKEKGDQKADE----
----------EAYEAEIQVEI-SELLEEHTEEYTQKM-EEYRTSLQQWKAWRKAQRAKKK
KR---KQAAEEHS-----YDETEEPHPEEDLVKPIPPEPTDRAVIEQEVRERATQSRRR

PF15625 // ENSGT00510000046611_0_Domain_0 (780, 967)

P
G-EPMLVPELSLAGSITPNNQ-CPRAEVLRREDVKKRSLYLKVLFNNKEVSRTVTRPLGA
DFRVHFGQ---IFNLQIVNWPESLALQVYE-TIGHSGPTLLA-EVFLPVPETTVVAGRAP
IE-EVEFSSNQHVTLDHEGVGSGVPFSFEADGSNQLILMT-----SGKVSHSVAWAIGEN
GIPLIP

ENSGT00510000046611_0_Linker_0_1 (967, 1243)

PLSQQNIGFRSALKRADAISSIGTSGLTDMKKLAKWAAESKLDPN-DPNNAPLM
QLISVATSGESYVPDFFRLEQLQQEFNFVSDQELSRSKRFRLLLLRSQEVPEFRNYKQIP
VYDREIMEKVFQDYEKRLRDRNVIETKEHIDTHRAMVAKYLQQVRESVINRFLIAKQHFL
LADMIVEEEVPNISSEGSGILGL-SLFKLAEQKRPLRPRR-----KGRKKVTAQN-----
--LSDGDIKLLVNIVRAYDIPVRKPAVSKFQQPSRSSRMFSE

PF00168 // ENSGT00510000046611_0_Domain_1 (1243, 1375)

KHAASPSTHSPNHNADYP
LGQVSVRPFVEVSFQRTVCHTTTAEGPNPSWNEELELPF---RAPNGDYSTASLQSVKDV
VFINIFDEVLHDVLEDDRERGSG-IHTRIERHWLGCVKIPFSTIYFQARIDGTFKIDIPP
VLLGYSKEQNMILERGFDSVRNLSEGSYITLFITIEPQLVPGESVQEKMSN----MLK-K
FESQEDEKLLQASEKFQAECAFKFPNRQCLTTVIDINGKTVFITRYLKPLNPPEELLNVY
PNNLQATAELVARYVSLIPFLPDTVSFAGICDLWSTSD---QFLDLLAGDEEEHAVLLCN
YFLSLGKKAWLVMGNAIPEGPTAYVLTWEQGHYLIWNPCSGHFYGQFDTFCPLKNVGCLI
GPDNIWFNIQRYDSPLRINFDVTKPKLWKSFFSRS-LPYPGLSSVQPEELIYQRSDKAAA
AELQD--RIEKILKEKIMDWRPRHLTRWNRYCTSTLRHFLPLLEKSQGEDVEDDHRAELL
KQLGDYRFSGFPLHMPYSEVKPLIDAVYSTGVHNIDVPNVEFALAVYIHPYPKNVLSVWI
YVASLIRNR

------------------CLFI---FERDRDR----AQLGEGQ-------RERETQNL--
-KQAPGPELSAQSLMRGSNPQAVRSPEPKS----------------------DAQPTEPP
R----------RLPPIPSAS-RTGFAEFSMRERMREKLQAARSKAESTLLQEIPTPRPRR
LQSPG-EKELETE--FGAEPGEEAQKTQQED-DSQSRSRVKFRDSVRKIKTKPPVPPGFP
SAEEAYNFFTFNFDPEPEESEEKP---KAKNRDGTTQE-EEG--EEEEPPVQGIHK----
----------TAEAFLWGLDHAAADFVAVRPADYESAHVRLQMEKELLFVPSRLT----V
PTYKKLPENV-QPR-YLEDEGLYIG-TRPDVPRTCQNIMENRLLTQEPGRRWFGDDGRIV
ALPNPIKPFPSRPPVLTQEQDFRAELETLYKKAVKYVHR-SQHMIGSGDSP--GNFQLDI
-DISGLIF-THHPCF-SREHVLAAK----LAQLYDQYLA---------------------
----------RHQRNKAKFLTDKLQALRNAVQTGLNPEKTHKSLDTTQKTINEYKSEIRQ
TRKLRDAEQEKDRMLLKTIIKVWK-EMKSLREFQRFTNTPLKLVLRKEKVDQKADE----
----------EAYEAEIQAEI-SELLEEHMEEHEQKM-EAYRAAYQQWKAWKKAQRAKKK
KKK---QAVEEHP-----EEEMGEPYPEEDPVKPVPPEPTDRALMEHQVRERAARSRRR

PF15625 // ENSGT00510000046611_0_Domain_0 (780, 967)

P
G-EPLLVPELSLAGSVTPNEQ-CPRVEVLRREDVKRRSIYLKVIFNDKEVSRTDSRPLGA
DFRVHFGQ---IFNLQIFNWPESLTLQVYE-TVGHSGTTLLA-EVFLPIPETTIVTGRAP
IE-EVEFSSNQHVTLDHEGVGSGMPFSFEADGSNQLILMT-----SGKVSNSVAWAIGEN
GIPLIP

ENSGT00510000046611_0_Linker_0_1 (967, 1212)

PLSQQNIGFRSALKRADAISSIGTSGLTDLKKLAKWAAESKLDPN-DPNNAPLM
QLISVTCPGESLLPGFPSARR-----------------RFPLTEH--------------P
-AEGQADARESVDYEKRLRDRNVIETKDHIDPHRAMVAKYLQQVRESVINRFLIAKHHFL
LSDLIVEEEVPN-----ISILGL-SLFKLAEQKRPLRPRR-----KGRKKVTAQN-----
--LSDGDIKVL

PF00168 // ENSGT00510000046611_0_Domain_1 (1212, 1375)

VNIIRAYDIPVRKPTASKFQQPSRSSRTFSEKHAASPTTHSPTHSADYP
LGQVLVRPFVEVSFQRTICHTTTAEGPNPSWNEELELPF---RAPNGDYSTSSLQSVKDD
VFINIFDEVLYDVLEDDRERGSG-IHTRIERHWLGCVKIPFSTIYFQAKIDGTFKIDIPP
VLLGYSKERSMIIERGFDSVRSLSEGSYITLFITMEPQLVPGEPVREKSLF-------VK
FDSQEDEKLLQATEKFQAECALKFPHRQCLTTVTDISGKTVFITRYLKPLNPPQELLEAC
PNNPQATAELVARYVSLIPFLPDTVSFAGICDLWSTSD---QFLDLLAGDEEEHAVLLCN
YFLSLGKKAWLVMGSAIPEGPTAYVLTREQSHYLIWNPCSGHFYGQFDTFCPLKSVGCLI
GPDNIWFNIQRHDSPLRINFDVTKPKLWKSFFSRS-LLYPGLSSVQPEELIYQRTDKAAA
AELQD--RIEKILKEKIMDWRPRHLTRWNRYCTSALRHFLPLLERSRGEDVEDDHRGELL
KQLGDYRFSGFPLHMPYSELKPLIEAVYSTGVHNIDVPNVEFALAVYIHPYPKNVLSVWI
YVASLIRNR

-----------MNPREEKVKIITEEFIENDED----ADMERQK-------KNSKVRRQP-
-RKKQPPTA-VPEEMVSEKSHLGNQE------E--------PVQEEPKTCLLSMTAQRGP
R----------SLPPIPSTS-RTGFAEFSMRGRMREKLQAARSKAESALLQEIPTPRPRR
LRSPR-KEELETE--FGTEPGKEVESTQQEI-DSQSHSRVKFRDSARKIKPKPQVPPGFP
SAEEAYNFFTFNFDPEPEESEKKP---KARHREGTNLKEEEG--EEEEPPAHRGE---KE
TDEEELLNGDDAEDFLLGLDHVADDFVAVRPADYESIHDRLQMEREMLFIPSRQT----V
PTYKKLPENV-QPR-FLEDEGLYTG-VRPEVSRTNQNIMENRLLVQDPERRWFGDDGRIL
ALPNPIKPFPSRPQVKTQELSIKAELETMYKKAVKYVHS-NQHMIRSGDPP--GNFQLDI
-DISGLLF-THHPCF-SREHVLAAK----LAQLYDQYLA---------------------
----------RHQRNKAKFLTDKLQALRYAVQTGLDPEKPHQSLDTIQKTINDYKSEIRQ
TRKLRDAEQEKDRTLLKTIIKVWK-EMKSLREFQRFTNTPLKLVLKKEKVDQKADE----
----------EAYEVEIQVEI-SELLEEHTEEYAQKM-EEYRTSLQQWKAWRKAQRAKKK
KR---KQAAEEHP-----DDETEEPYPEEDLVKPIPPEPIDRAVIEQEVRERATQSRRR

PF15625 // ENSGT00510000046611_0_Domain_0 (780, 967)

P
G-EPMLVPELSLAGSITPNNQ-CPRAEVLRREDVKKRSLYLKVLFNNKEVSRTVTRPLGA
DFRVHFGQ---IFNLQIVNWPESLALQVYE-TIGHSGPTLLA-EVFLPIPETTVVTGRAP
IE-EVEFSSNQHVTLDHEGVGSGVPFSFEADGSNQLILMT-----SGKVSHSVAWAIGEN
GIPLIP

ENSGT00510000046611_0_Linker_0_1 (967, 1211)

PLSQQNIGFRSALKRADAISSIGTSGLTDMKKLAKWAAESKLDPN-DPNNAPLM
QLISVATSGESYVPDFFRLEQLQQEFNFVSDQELNRSKRFRLLLLRSQEVPEFRNYKQIP
VYDREIMEKVFQDYEKRLRDRNVIETKEHIDTHRAIVAKYLQQVRESVINRSLIAKQYFL
LADMIVEEEVPNIS-----ILGL-SLFKLAEQKRPLRPRR-----KGRKKVTAQN-----
--LSDGDIKL

PF00168 // ENSGT00510000046611_0_Domain_1 (1211, 1375)

LVNIVRAYDIPVRKLAVSKLQQPSRSSRMFSEKRAASPSIHSPNHNADYP
LGQVLVRPFVEVSFQRTVCHTTTAEGPNPSWNEELELPF---RAPNGDYSTASLQSVKDV
VFINIFDEVLHDVLEDDRERGSG-IHTRIERHWLGCVKIPFSTIYFQARIDGTFKIDIPP
VLLGYSKERNTILERGFDSVRNLSEGSYITLFITIEPQLVPGESVQG------------K
FESQEDEKLLQASEKFQAECAFKFPNRQCLTTVIDINGKTVFITRYLKPLNPPEELLNVH
PNNLQATAELVARYVSLIPFLPDTVSFAGICDLWSTSD---QFLDLLAGDEEEHAVLLCN
YFLSLGKKAWLVMGNAIPEGPTAYVLTWEQGHYLIWNPCSGHFYGQFDTFCPLKNVGCLI
GPDNIWFNIQRYDSPLRINFDVTKPKLWKSFFSRS-LPYPGLSSVQPEELIYQRSDKAAA
AELQD--RIEKILKEKIMDWRPRHLTRWNRYCTSTLRHFLPLLEKSHGEDVEDDHRAELL
KQLGDYRFSGFPLHMPYSEVKPLIDAVYSTGVHNTDVPNVEFALAVYIHPYPKNVLSVWI
YVASLIRNR

-----------MNPREEKVKIITEEFTEND----EEADVGRWKKN-------SKAERHR-
-KKKQPPTA-GPGEMVSEKAHGSSQQEP--------------GQEESQTRLVSVPARRGP
R----------SLPPIPSTS-RTGFAEFSMRERMREKLQAARSKAESALLQEIPTPRPRR
LRSPR-EKETETA--FGTEPGKEIQATHQEE-DSQSYSRVKFHDAVRKIKSKPQAPPGYP
SAEEAYNFFTFNFDPEPEEPEVKA---KVRARDGTNQKEEEEEGEEEESPAG----GVNK
TDEEELLSGKDAEDLLLGLDPEADDSVAVRPAEYESIHTWLEKEKEILFIPSRQA----V
PICEKLPENV-QPR-FPEDEGLYTG-ARPEVTRANQNVAESRLLRQESGRKWFGDDGRIL
ALPSPIRPFPSRPPRLAQEPSAKAGLETLYRKAVKYVHR-TQHMIGSGDPP--GNFQLDI
-DISGLIF-THHPCF-SREHVLAAK----LAQLYDQYLA---------------------
----------RHRRNKAKFLTDKLQALRNAVQTGLHPEKPHQSLDATQKTVNEYKSEIRE
----RNAEQEKDRTLLKTIIKVWK-EIKSLREFQRFTNTSLRLVLRKEKVDQKADE----
----------EAYEAEIQAEI-SELMEEHTEEYEQKM-EAYRASYQQWRAWKKAQKVKKK
KKKQ----AEEHPE----GQAEEESYPGEEPAKPVPPELPDQVALEQQVRERAAHSRRR

PF15625 // ENSGT00510000046611_0_Domain_0 (780, 967)

P
S-EPVLLPELSLAGSVTPNDQ-CPRVEVLRREDVKRRSVYLKVLFNSKEVSRTVSRQLGA
DFRVHFGQ---IFNLQIFNWPESLTLQVYE-TVGHSSTTLLA-EVFLPIPETTVVTGRAP
TE-EVEFSSNQHVTLDHEGVGSGVPFSFEADGSNQLTLMT-----SGKVSHSVAWAVGDN
GVPLIP

ENSGT00510000046611_0_Linker_0_1 (967, 1239)

PVSQQNAGFRSALKRADAISSIGTSGLTDMKKLAKWVAESKLDPN-DPNNAPLM
QLISVATSGESYVPDFFRLEQLQQEFNFVSDEELNRSKRFRLLRLRSQEVPEFRNYKQIP
AYDREIMERVFQDYEKRLRDKSVIETKDHMDTHRAIVAKYLQQVRESVVNRFLIAKHHFL
LADLVVEEEVPNISSEGSGSLGL-SLFKLAEQKRPLRPRR-----RGRKKVTAQN-----
--LSDGDIKLLVNICRAYDIPVRKPAASKFQQPSRSSR

PF00168 // ENSGT00510000046611_0_Domain_1 (1239, 1374)

TFSEKHAASPSAHSPNQSPDNP
LGQVLVRPFVEVSFQRTICHTTTAEGPNPSWNEELEFPF---RAPNGDYSSASLQSVKDD
VFINIFDEVLCDVLEDDRERGSG-IHTRIERHWLGCVKIPFSTIYFQGRIDGTFKIDTPP
VLLGYSKERNMLIERGFDSVRSLSEGSYITLFITIEPQLVPGESIQEKMSD----MLK-K
FDSQEDEKLLQATEKFQVECALKFPSRQCLTTVIDISGKTVFITRYLKPLNPPQELLNAY
PSNPQATAELVARYVSLIPFLPDTVSFAGICDLWSTSD---QFLDLLAGDEEEHAVLLCN
FFLFLGKKAWVVMGNAIPEGPTAYVLTWEQNHYLIWNPCSGHFYGQFDTFCPLKSVGCLI
GPDNIWFNIQQYDSPLRINFDVTKPKLWKPFFSRS-LPYPGLSSVQPEELIYQHTDKTAA
AELQD--RIEKMLKEKIMDWRPRHLTRWNRHCISTLRHFLPLLERSQGEGVDDDHRAELL
KQLGDYRFSGFPLHMPYSEVKPLIEAVYSTGVHNIDVPNVEFALAVYIHPYPKNVLSVWI
YVASLIRNR

-----------MNPREEKVKIITEQFIENDED----ADMESQK--------SSKVRRRP-
-RKKQPPTA-VPEEMVSEKSHLGNQQ------E--------PVQEKPKTCLLSMTARRGP
R----------SLPPIPSTS-RTGFAEFSMRGRMREKLQAARSKAESALLQEIPTPRPRR
LRSPS-KKELETE--FGTEPGKEVESAEQEI-DSQSHSRVKFRDSARKSKPKPQVPPGFP
SAEEAYNFFTFNFDPEPEDSEKKT---KARHREGTHQEEEEG--EEEEPPAQGRG---KE
TDEEEFLNGDDAEDFLLGLDHMADDFVAVIPADYESIHDRLQMEREMLFIPSRQT----V
PTYKKLPENV-QPR-FLEDEGLYTG-VRPEVSRTNQNIMENRLLVQDPERRWFGDDGRIL
ALPNPIKPFPSRPPVETQELSIKAELEIMYKKAVKYVHS-SQHMIRSGDPP--GNFQLDI
-DISGLLF-THHPCF-SREHVLAAK----LAQLYDQYLA---------------------
----------RHQRNKAKFLTDKLQALRNAVQTGLDPEKPHQSLDTIQKTINDYKSEIRQ
TRKLRDAEQEKDRTLLKTIIKVWK-EMKSLREFQRFTNTPLKLVLRKEKVDQKADE----
----------EAYEAEIQVEI-SELLEEHTEEYAQKM-EEYRTSLQQWKAWRKAQRAKKK
KR---KQAAEEHP-----YDETEESYPEEDLVKPIPPEPTDRAVIEQEVRERATQSRRR

PF15625 // ENSGT00510000046611_0_Domain_0 (780, 967)

P
G-EPMLVPELSLAGSITPNNQ-CPRAEVLRREDVKKRSLYLKVLFNNKEVSRTVTRPLGA
DFRVHFGQ---IFNLQIVNWPESLALQVYE-TIGHSGPTLLA-EVFLPIPETTVVTGRAP
IE-EAEFSSNQHVTLDHEGVGSGVPFSFEADGSNQLILMT-----SGKVSHSVAWAIGEN
GIPLIP

ENSGT00510000046611_0_Linker_0_1 (967, 1210)

PLSQQNIGFRSALKRADAISSIGTSGLTDMKKLTKWAAESKLDPN-DPNNAPLM
QLISVATSGESYVPDFFRLEQLQQEFNFVSDQELNRSKRFRLLLLRSQEVPEFRNYKQIP
IYDREIMEKVFQDYEKRLQDRNVIETKEHIDTHRAIVAKYLQQVRESVINRFLIAKQYFL
LADMIVEEEVPNIS-----ILGL-SLFKLAEQKRPLRPRR-----KGRKKVTAQN-----
--LSDGDIK

PF00168 // ENSGT00510000046611_0_Domain_1 (1210, 1375)

LLVNIVRAYDIPVRKPAVSKFQQPSRSSRMFSEKHAASPSTHSPNHNADYP
LSQVLVRPFVEVSFQRTVCHTTTAEGPNPSWNEELELPF---KAPNGDYSTASLQSVKDV
VFINIFDEVLHDVLEDDRERGSG-IHTRIERHWLGCVKIPFSTIYFQARIDGTFKIDIPP
VLLGYSKERNMILERGFDSVRNLSEGSYITLFITIEPQLVPGESVQE------------K
FESQEDEKLLQASEKFQAECAFKFPNRQCLTTVIDINGKTVFITRYLKPLNPPEELLNVY
PNNLQATAELVARYVSLIPFLPDTVSFAGICDLWSTSD---QFLDLLAGDEEEHAVLLCN
YFLSLGKKAWLVMGNAIPEGPTAYVLTWEQGHYLIWNPCSGHFYGQFDTFCPLKNVGCLI
GPDNIWFNIQRYDSPLRINFDVTKSKLWKSFFSRS-LPYPGLSSVQPEELIYQHSDKAAA
AELQD--RLEKILKEKIMDWRPRHLTRWNRYCTSTLRHFLPLLEKSHGEDVEDDHRAELL
KQLGDYRFSGFPLHMPYSEVKPLIDAVYSTGVHNIDVPNVEFALAVYIHPYPKNVLSVWI
YVASLIRNR

-----------RTGNNSSSNIISYGCYT-EHAD--V---GRRK-------KNSKAQRRQ-
-RKKQP-PTTDPEDMVSEKSHNGSQQ---E-----------PAQEEPETHLLGMTAKRGP
R----------SLPPIPSAS-RTGFAEFSMRERMREKLQAARSKAESALLQEIPIPKPRR
LRSPS-SRELETE--FGTEPGKEVQG-TQQE-DSQSYSRVKFRDPVRKTKSKTQAPPGFP
SAEEAYNFFTFNFDPEPEELEGKK---QIKGRDGSDQEEESGEE----L--PVQGKERRG
RKEEEE--KKKGEQQ---------------KEE-------KETRKRILLGEEE-------
-VYIQVC---------HQGRNWF-C-TRLHIPR--KKYSGCSLMLNPQERKWFGDDGRIL
ALPSPIKPFSSRPPLFTPAQSIKAELETLYKKAVKYVHS-SQHMIGSGDPP--GNFQLDI
-DISGLIF-THHPCF-SREHVLASK----LAQLYDQYLA---------------------
----------RHQRNKAKFLTDKLQALRNAVQTGLDPEKLHQPLDTTQKTINEYKSEIRQ
TRKLRDAEQERDRTLLKTIIKVWK-EMKSLREFQRFTNTPLKLVLKKEKVDKKADE----
----------EVYEAEIQAEI-RELLEEHTEAYEQKM-EEYRTSHQQWKAWKKAQRAKKK
KKKQAA---EE----DLDEE-TEELPAEEGPVKPIPPEPTDPAAIEQRVRERAAHSRRR

PF15625 // ENSGT00510000046611_0_Domain_0 (780, 967)

P
G-EPMLVPELSLAGSVTPNDQ-CPRVEVLRRDDVKRRSVYLKVLFNSKEVSRTVSRQLGP
DFRVHFGQ---IFNLQIFNWPESLTLQVYE-TVGYSSTSLLA-EVFLPIPETTVVTGRAP
TE-EVEFSSNQHVTLDHEGVGSGVPFSFEADGSNQLILMT-----SGKVSHSVAWAIGEN
GIPLIP

ENSGT00510000046611_0_Linker_0_1 (967, 1210)

PLSHQNIGCRSALKRADAISSIGTSGLTDMKKLAKWAAESKLDPN-DPSNAPLM
QLISVATSGESYVPDFFRLEQLQQEFNFISDEELNRSKRFRLLHLRNQEVPEFRNYKQIP
AYDREIMEKIFQDYEKRLRDRNVIETKDHVDTHRAMVAKYLQQVRESVVNRFLIAKHHFL
LTDLVVEEEVPNIS-----ILGT-SLFKLAEQKRPLRPRR-----KGRKKVTAQN-----
--LSDGDIK

PF00168 // ENSGT00510000046611_0_Domain_1 (1210, 1375)

LLVNIVRAYDIPVRKPTASKFQQPSRSSRTFSEKHVTSPSPHSPTPSADFP
LSQVLVRPFVEVSFQRTICHTTTAEGPNPSWNEELELPF---RAPNGDYSTASLQSVKDD
VYINIFDEVVYDILEDDRERGSG-IHTRIERHWLGCVKIPFSTIYFQARVDGTFKIDIPP
VLLGYSKERNMFMERGFDAVRSLSDGSYITLFITIEPQLVPGESVREKV----------S
FESQEDEKLLQATEKFQAECALKFPNRRCLTTVIDISGKTVFITRYLKPLNPPQELLNFY
PDNQQATAELVARYVSLIPFLPDTVSFAGICDLWSTSD---QFLDLLAGDEEEHAVLLCN
YFLWLGKKAWLLMGSAIPEGPTAYVLTWEKNHYLIWNPCSGHFYGQFDTFCPLKSVGCLI
GPDNVWFNIQQYDSPLRINFDVTKPKLWKSFFSRS-LPYPGLSSVQPEELIYQRTDKAAA
AELQD--RIEKILKEKIMDWRPRYLTRWNRYCTSTLRHFLPLLESSQGEDVEDDHQAELL
KQLGDYRLSGFPLHMPYSEVKPLIEAVYSTGVHNIDVPNVEFALAVYIHPYPKNVLSVWI
YVASLVRNR

------------------------------------------------------------
------------------------------------------------------------
------------LPPAPSTS-RAGFAERSVRERMREKIKAARSKAEVTLSQDDHSPRPRR
LKNIRE-RKTEVSLDE-S-DSDKFRE--MQEDESRILSKVKFRDSVKKMKQKSSVQNDFP
SAEEAYNFFTFNFDSEPENGA--------------------------------GAQKMSE
LDEDVRL---VKDDL-FNIGQTAEDLLVMKPAECESYSEQVQKEKEFLFIPSRLT----V
PTSQKMPGNV-QPR-YLEDEGLYTG-ERPFVSPSNQNIVENRLLRQEQGKGWFGDDGKIL
ALPNPIKQSSMRLPIFSLEEGIAPELETVYRKAIKMTAA-NQYLVAPGDFQ--GPFQLDI
-DISGLIF-THHPCF-SREHVLAAK----LAQLYDQYLA---------------------
----------RKQKNLTKLLTDKLHALRNAVQCRVGSGGAGAPGPIAQQSIPEYKFEIRQ
TRRLRDAEQEKDRMLLKTIIKVWK-QMKSLRDFQKFTNTPMKLYLRKEEVDQRSDE----
----------KAYEAEIQAEI-SELIEEYMEEYDKKM-EEYRTELKEWKSWRKAQKSRKK
KKKKDLQ------E---EKDSVEDCDLGEEPVKPIPPKMVNNLEIEQQVREKADNLRRKP
G-EPALIPELVLSGSITPSEL-CPRAEVLRREDVKKRSVFIKVLFNSKEVSRTVTRPISS
DFRVHFGQ---IFNLQIFNWPESLKLQIYE-TTGMSSTTLLA-EVFIPVPETTVLTGSAP
ME-EIEFSSNQRVVLDHEGVGSDVSFSFEADGSNQMTLMT-----SGKVSNSVSWAVGEK
GIPLIPPVSQQTTGIPSALKNIDAIASIGTSGLNDMKKLAKWAAEAKLDPN-DPNNAALM
QMIMVATSGEAHVPDFFRLEQLQQEFNFVSDEEFNRSKRFRLLQLRNEEVAEFRNYKQVP
LHEREISEKLFQDYEKRLHERNVIDSKHYLDARRAVVANYLQKVRESVINRFLVAKHHFL
LSDLVNEEEIPSLGSEGPGILGL-GLFKLAEPKRPLKPRR-----KERKKVTAQN-----
--LSDGDIK

PF00168 // ENSGT00510000046611_0_Domain_1 (1210, 1334)

LLVNVIRAFDIPVRKPVMSKPQQPSKSSRSFNEMFAASPSAQSPTDSVDWA
FDQVLVRPFVEVSFQRTVCRTTTAEGPNPNWNEELELPF---RAPNGDYSTHSLQSVKDE
VFINVFDEVLHDVTEDDCDRRSG-IHTCVERRWLGCVKIPFTTIYFQAKIDGTFKVDIPP
VLLGYSKEKNLGMERGYDSVRNLSEGSYITLFITIEPQLVPGESVREKMNE----MLK-K
FDTQEDEKLLQAAEKYEAECTSKFPSRQCLTTVIDLNGKTVFITRYVKPLNPPQELLDAY
PDSSQTTAELVARYVALIPFLPDSVSFAGICDLWSTSD---QFLDLLAGDEEEHAVLLCN
YFLGMGKKAWLIIGNAIPEGQTAYVLTLEQSQYVIWNPSTGSFYRQYDTFCPLQNVYCLI
SCDNIWFNIQEHDSPVRISFDISKPKLWKPFFSRS-LPYPGLSSVQPEELVYQHSDKAAA
VELQG--RIEKILKEKIMEWRPRHLTRWNRYCTSTLRNFLPLLEQNQGKDVEDDHQAELQ
KQLGDYRVSGFPIHMPFSEVRSLVEAVHSTGVHTIDVSNVEFALAVYIHPYPQSVLSVWI
YVASLVRNR

-----------MNPKEEKVKIITEEFLENEEE----AHAGRQK-------KSSKDKRQK-
-RKKQPPTA-DSEEMVSPKPHDDNQQEPTQ------------EE--PETRLLSTTTRRGP
Q----------SLPPIPAAS-RTGFAEFSMRERMREKLQAARSKAESALLQEIPTPRPRR
LRSPS-EKESETE--FGMEPGKEVLRVQQEN-DSQSYSRVKFRDSARKSKSKPPVPPGFP
SAEEAYNFFTFNFDPEPEEPEEKP---NAKVRDEVNQEEEEG--DEEEPPVQE--E-IKK
TDEEGLLNGKDAEDFLLGLDHMAEDFVVVRPADYESLHVQMQMEKGILFIPSSLT----V
PTYKKLPENV-QPR-FLEDEGLYIG-ERPEVPRTNQNIMENRLLTQEPGRGWFGDDGRIL
ALPNPVKPFPARSPALKQEQNIKAELEMVYKKAVKYVSN-SPHMIGAGDPP--GNFQLDI
-DIVGLIF-THHPCF-SREHVLAAK----LAQLYDQHLA---------------------
----------RRQRNKAKFLTDKLQALRNAVQTGLNPAKPHKSLDTAQRAIKEYKSEIRQ
TRKLRDAEQEKDRTLLKAIIKVWK-EMKSLREFQRFTNTPLKLVLRKEKVDQKADE----
----------EAYEAEIQAEI-RELLEEHMEDYEQKM-EEYRRAHQQWKAWKKAQRAKKK
KKK---QTAEERP-----DEETEEPCPGEDPVKPVPPELTDQAVIEEQVRERAAQSRRKP
G-EPMLVPELSLAGTMTPNDQ-CPRVEVLRREDVKRRSVHLKVLFNKKEVSRTVSRPLGA
DFRVHFGQ---IFNLQIFNWPESLTLQVYE-TVGHSGTTLLA-EVFLPIPETTVVSGRAP
IE-EVEFSSNQHVTLDHEGVGSGVPFSFEADGSNQLILMT-----SGKVSNSVAWATGEN
GVPLIPPLSQQNTGFRSALKRADAISSIGTSGLTDMKKLAKWAAESKLDPN-DPNNAPLM
QLISVATSGESYVPDFFRLEQLQQEFNFVSDEELNRSKRFRLLHLRSQAVPEFRNYKQIP
AYDREIMEKVFQDYEKRLRDRKVIETKDHIDTHRAVVAKYLQQVRESVVHRFQIAKHHFL
LSDLIVEEEVPNISSEGSGVLGL-SLFKLAEQKRPLRPRR-----KGRKKVTAQN-----
--LSDGDIK

PF00168 // ENSGT00510000046611_0_Domain_1 (1210, 1334)

LLVNIIRAYDIPVRKPTASKFQQPSRSSRTVSEKHAASPTTHSPAHGADYP
LSQVLVRPFVEVSFQRTICHTTTAEGPNPSWNEELELPF---RAPNGDYSTASLQSVKDD
VFINIFDEVLYDVLEDDRERGSG-IHTRIERHWLGCVKIPFSTIYFQARIDGTFKIDIPP
VLLGYSKERN-IIERGFDPVRSLSEGSYITLFITIEPQLVPGESVREKMSV----MLKKK
FDSQEDEKLLQATEKFQAECALKFPNRQCLTTVIDISGKTVFITRYLKPLNPPQELLNVY
PSNSQATAELVARYVSLIPFLPDTVSFAGICDLWSTSD---QFLDLLAGDEEEHAVLLCN
YFLFLGKKAWLMMGNAIPEGPTAYVLTWEQSHYLIWNPCSGHFYGQFDTFCPLKSVGCLI
GPDNIWFNIQRYDSPLRINFDVTKPKLWKSFFSRS-LPYPGLSSVQPEELIYQGTDKMAA
AELQD--RIEKILKEKIMDWRPRHLTRWNRYCTSTLRHFLPLLERSQGEDVEDDHGAELL
KQLGDYRFSGFPLHMPYSEMKPLIEAVYSTGVHNIDVPNVEFALAVYIHPYPKNVLSVWI
YVASLIRNR

-----------MNPREEKVKIITEEFIENDED----ADMERQK-------KNSKVRRQP-
-RKKQPPTT-VPEEMVSEKSHLGNQQ------E--------PVQEEPKTYLLSMTARRGP
R----------SLPPIPSTS-RTGFAEFSMRGRMREKLQAARSKAESALLQEMPTPRPRR
LRSPS-KKELETE--FGTEPGKKVESTQQEI-DSQSHSRVKFRDSARKIKPKPQVPPGFP
SAEEAYNFFTFNFDPEPEDSEKKT---KASHREGTNQEEEEG--EEEEPPAQGGG---KE
TDEEELLNGDDAEDFLLGLDHMVDDFIAVRPADYESIHDRLQMEREMLFIPSRQA----V
PTYKKLPENV-QPR-FLEDEGLYTG-VRPEVSRTNQNIMENRLLVQDPERRWFGDDGRIL
ALPNPIKPFPSRPPVETQELSIKGELETMYKKAVKYVHS-SQHMIRSGDPP--GNFQLDI
-DISGLLF-THHPCF-SREHVLAAK----LAQLYDQYLA---------------------
----------RHQRNKAKFLTDKLQALRNAVQTGLDSEKPHQSPDTIQKTINDYKSEIRQ
TRKLRDAEQEKDRTLLKTIIKVWK-EMKSLREFQRFTNTPLKLVLRKEKVDQKADE----
----------EAYEAEIQVEI-SELLEEHTEEYAQKM-EEYRTSLQQWKAWRKAQKAKKK
KR---KQAAEEHP-----YDETEEPYPEEDLVKPIPPEPTDRAVIEQEVRERATQSRRR

PF15625 // ENSGT00510000046611_0_Domain_0 (780, 967)

P
G-EPMLVPELSLAGSITPNNQ-CPRAEVLRREDVKKRSLYLKVLFNNKEVSRTVTRPLGA
DFRVHFGQ---IFNLQIVNWPESLALQVYE-TIGHSGPTLLA-EVFLPIPETTVFTGRAP
IE-EMEFSSNQHVTLDHEGVGSGVPFSFEADGSNQLILMT-----SGKVSHSVAWAIGEN
GIPLIP

ENSGT00510000046611_0_Linker_0_1 (967, 1211)

PLSQQNIGFRSALKRADAISSIGTSGLTDMKKLAKWAAESKLDPN-DPNNAPLM
QLISVATSGESYVPDFFRLEQLQQEFNFVSDQELNRSKRFRLLLLRSQEVPEFRNYKQIP
VYDREIMEKVFQDYEKRLRDRNVIETKEHIDTHRAIVAKYLQQVRESVINRFLIAKQYFL
LADMIVEEEVPNIS-----ILGL-SLFKLAEQKRPLRPRR-----KGRKKVTAQN-----
--LSDGDIKL

PF00168 // ENSGT00510000046611_0_Domain_1 (1211, 1375)

LVNIVRAYDIPVRKPAVSKFQQPSRSSRMFSEKHAASPSTHSPNHNADYP
LGQVLVRPFVEVSFQRTVCHTTTAEGPNPSWNEELELPF---RAPNGDYSTASLQSVKDV
VFINIFDEVLHDVLEDDRERGSG-IHTRIERHWLGCVKIPFSTIYFQARIDGTFKIDIPP
VLLGYSKERNMILERGFDSVRNLSEGSYITLFITIEPQLVPGESVQE------------K
FESQEDEKLLQASEKFQAECAFKFPNRQCLTTVIDINGKTVFITRYLKPLNPPEELLSVY
PNNLQATAELVARYVSLIPFLPDTVSFAGICDLWSTSD---QFLDLLAGDEEEHAVLLCN
YFLSLGKKAWLVMGNAIPEGPTAYVLTWEQGHYLIWNPCSGHFYGQFDTFCPLKNVGCLI
GPDNIWFNIQRYDSPLRINFDVTKPKLWKSFFSRS-LPYPGLSSVQPEELIYQRSDKAAA
AELQD--RLEKILKEKIMDWRPRHLTRWNRYCTSTLRHFLPLLEKSQGDDVEDDHRAELL
KQLGDYRFSGFPLHMPYSEVKPLIDAVYSTGVHNIDVPNVEFALAVYIHPYPKNVLSVWI
YVASLIRNR

-----------MNPREEKVKIITEEFIENDGD----ADMGRQN-------KTSKVRRQP-
-RKKQPPTA-VPKEMVSEKSHLGNQQ------V--------PVQEEPKTRLLSMTVRRGP
R----------SLPPIPSTS-RTGFAEFSMRGRMREKLQAARSKAESALLQEIPTPRPRR
LRSPS-KKELETE--FGTEPGEEVERTQQEV-DSQSYSRVKFRDSARKIKPKPQVPPGFP
SAEEAYNFFTFNFDPEPEGSEEKP---KARHRAGTNQEEEEG--EEEEPPAQGGG---KE
MDEEELLNGDDAEDFLLGLDHVADDFVAVRPADYESIHDRLQMEREMLFIPSRQT----V
PTYKKLPENV-QPR-FLEDEGLYTG-VRPEVARTNQNIMENRLLMQDPERRWFGDDGRIL
ALPNPIKPFPSRPPVLTQEQSIKAELETLYKKAVKYVHS-SQHVIRSGDPP--GNFQLDI
-NISGLIF-THHPCF-SREHVLAAK----LAQLYDQYLA---------------------
----------RHQRNKTKFLTDKLQALRNAVQTSLDPEKPHQSLDTIQKTINEYKSEIRQ
TRKFRDAEQEKDRTLLKTIIKVWK-EMKSLREFQRFTNTPLKLVLRKEKADQKADE----
----------EAYEAEIQAEI-SELLEEHTEEYAQKM-EEYRTSLHQWKAWRKAQRAKKK
KR---KQAAEEHP-----DDEIAEPYPEEDLVKPSPPEPTDRAVIEQEVRERAAQSRRRP
W-

PF15625 // ENSGT00510000046611_0_Domain_0 (783, 967)

EPTLVPELSLAGSITPNDQ-CPRAEVSRREDVKKRSVYLKVLFNNKEVSRTVSRPLGA
DFRVHFGQ---IFNLQIVNWPESLTLQVYE-TIGHSSPTLLA-EVFLPIPETTVVTGRAP
TE-EVEFSSNQHVTLDHEGVGSGLPFSFEADGSNQLTLMT-----SGKVSHSVAWAIGEN
GIPLIP

ENSGT00510000046611_0_Linker_0_1 (967, 1210)

PLSQQNIGFRSALKKADAISSIGTSGLTDMKKLAKWAAESKLDPN-DPNNAPLM
QLISVATSGESYVPDFFRLEQLQQEFNFVSDQELNRSKRFRLLHLRSQEVPEFRNYKQVP
VYDREITEKIFQDYEKRLRDRNVIETKEHIDTHRAIVAKYLQQVRESVINRFLIAKQYFL
LADMIVEEEVPNIS-----ILGL-SLFKLAEQKRPLRPRR-----KGRKKVTAQN-----
--LSDGDIK

PF00168 // ENSGT00510000046611_0_Domain_1 (1210, 1375)

LLVNIVRAYDIPVRKPAVSKFQQPSRSSRTFSEKRAASPSTYSPTHNADYP
LSQVLVRPFVEVSFQRTVCHTTTAEGPNPSWNEELELPF---RAPNGDYSTASLQSVKDV
VFITIFDEVLHDVLEDDRERGSG-IHTRIERHWLGCVKIPFSTIYFQARIDGTFKIDIPP
VLLGYSKERNMILERGFDSVRSLSEGSYITLFITIEPQLVPGESIRE------------K
FESQEDEKLLQATEKFQAECALKFPNRQCLTTVIDISGKTVFITRYLKPLNPPQELLNVY
PNNLQATAELVARYVSLIPFLPDTVSFGGICDLWSTSD---QFLDLLAGDEEEHAVLLCN
YFLSLGKKAWLLMGNAIPEGPTAYVLTWEQGHYLIWNPCSGHFYGQFDTFCPLKNVGCLI
GPDNIWFNIQRYDSPLRINFDVTRPKLWKSFFSRS-LPYPGLSSVQPEELIYQRSDKAAA
AELQD--RIEKILKEKIMDWRPRHLTRWNRYCTSTLRHFLPLLEKSQGEDVEDDHRAELL
KQLGDYRFSGFPLHMPYSEVKPLIDAVYSTGVHNIDVPNVEFALAVYIHPYPKNVFSVWI
YVASLIHNR

-----------MNANDEKVKIISEDFTGDGAD----TEAGRRK-------KNSKVRRQQ-
-RKKKPPAS-PPEEMVSDKFQDGGQQ------E--------VVEEEPETNLLSLTARWGP
R----------SLPPIPSAS-RTGFAEFSMRERMREKLQAARSKAESALLRDVPTPRPRR
LRSPSREKETETE--FGTEPSTEVQDTQKEDDDTKSYSRIKFRDSVRKIKSKPQLPPGFP
SAEEAYNFFTFNFDPEPEESEEKSPV---KGGERAHQEDQEG--E-EGTQAQERA---KK
TEEEELLNGKDAEDFLLGLDPTAHDFVAVRAAEYKSARIQLQKEKEILFTPSRLT----V
PTYKKLPENI-QPR-FLEDEGLYIG-ARPEVARTNENIMENRLLIQEPGSKWFGDDGRIL
ALPSPIKPFPSRPSLSTWEQSPKAGLETLYKKAEKYVHS-RQHMIGSGDPP--GNFQLDI
-DISGLIF-THHPCF-SREHVLASK----LAQLYDQYLA---------------------
----------RQQRNKTKFLTDKLQALRKAVQTSLNPEKPHQSLDTTQKTINEYKSEIRQ
TRKLRDAEQEKDRTLLKTIIKVWK-EMKSLREFQRFTNTPLKLVLRKEKVDPKLDE----
----------DAYEAEIQAEI-HELLEEHMEEYATKM-EEYRTSHQQWKAWRKAQRAKKK
KK---KQTAEEHLE---E-EEAEEPFPEEEVTKPIPPEPTDPAVIEQQVRERAAHSRRR

PF15625 // ENSGT00510000046611_0_Domain_0 (780, 967)

P
G-EPTLIPELSLAGNVTPNDQ-CPRVEVSRREDVRRRSVYLKVVFNSKEVSRTVSRPLGA
DFRVHFGQ---IFNLQIFNWPESLMLQVYE-TIGHSGTTLLA-EVFLPIPETTIVTGRAP
IE-EVEFSSTQHVTLDHEGVGSGVPFSFEADGSNQLTLMT-----SGKVSHSVAWAVGEN
GIPLIP

ENSGT00510000046611_0_Linker_0_1 (967, 1210)

PLSQQNIGFRSALKRADAISSIGTSGLTDMKKLAKWAAESKLDPN-DPNHAPLM
QLISVANSGESYVPDFFRLEQLQQEFNFVSEEELNRSKRFRLLHLRSQEVPEFRNYKQIP
VYDREIMEKVFQDYEKRLRDRNVIETKDHLDMHRATVAKYLQQVREAVVNRFLTAKHHFL
LTDLVVEEEVPNISSEGSGILGL-SLFKLAEQKRPLRPRR-----KGRKKVTSQN-----
--LSDGDIK

PF00168 // ENSGT00510000046611_0_Domain_1 (1210, 1375)

LLVNIIRAYDIPVRKPVVSKFQQPSRSSRTFSEKQTASPSTHSPLHNADYP
LGQVLVRPFVEVSFQRTICHTTTAEGPNPSWNEELELPF---RAPNGDYSTASLQSVKDD
VYINIFDEVLYDILEDDRERGSG-IHTRIERHWLGCVKIPFSTIYFQARIDGTFKIDIPP
VLLGYSKERNIIMERAFDSARSLSEGSYITLFITIEPQLVPGEPMREKMSD----MLK-K
FDTQEDEKLLQATEKFQAECALKFPQRQCLTTVTDMTGKTVFITRYLKPLNPPQELLHVY
PNNPQATAELVARYVSLIPFLPDSVSFAGVCDLWSTSD---QFLDLLAGDEEEHAVLLCN
YFLFLGKKAWLVMGSAIPEGPTAYVLTWEKNYYLIWNPCSGHCYGQFDAFCPLKSVGCLI
GPDNIWFNIQHHDSPLRINFDVTKPKLWKSFFSRS-LPYPGLSSVQPEELIYQHTDKAVA
AELQD--RIEKILKEKIMDWRPRHLTRWNRYCTSTLRHFLPLLERSQGEDIEDDHRAELL
KQLGDYRFSGFPLHMPYSEVKPLVEAVYSTGVHNIDLPNVEFALAVYIHPYPKNVLSVWI
YVASLVRNR

-----------MNPEEEKVKIITEESTEDDQE----ADVGRRR-------KSSKVQRQR-
-RKRQPPTA-DPKEMVSEKAHVGSQQEL--------------GQEEPETHLLSMPARRGP
R----------SLPPIPSMS-RTGFAEFSMRERLREKLQAARSKAESVLLQEIPTPRPRR
LRSPG-EKVSETG--LGTEPSEEVQAAHHRD-DSTSYSRIKFRDAVQKIKSKPQAPPGFP
SAEEACNFFTFNFDPEPEQPALKA---KGKDRDGAKQEEEE---GEEESPAG----GVSR
TDDEELLGDRDTKDFLLGLDPAAEDFVAIRPAEYEGVHTRLEKEKEILFVPSRRA----V
PTYKKLPENV-QPR-FLEDEGLYTG-ARPEMSRTNQNIMENRLLQQDPGRKWFGDDGRIL
ALPSPIKPFPSRPPPLAQELSDKAGLETLYKKAVKYAHR-TQHTIGSGDPL--GNFQLDI
-DVSGLIF-THHPCF-SREHVLAAR----LAQLYDQYLA---------------------
----------RHQRNKAKFLTDKLQALRNAVRSGLHPEKPHQSLDATQRTINEYKSEIRE
TRKLRDAEQEKDRTLLRTIIKVWK-EMKALREFQRFTNTPLKLVLRKEKVNQKAEE----
----------EAYEAEIQAEV-SELMEEHTEEYEQKM-EEYRASYQQWKVWRRAQKAKKK
KKKQ----VEECPE----GETEDELSPGEEPTKPALPEPPDRAALEQQARERAAHIRRR

PF15625 // ENSGT00510000046611_0_Domain_0 (780, 967)

P
G-EPALLPELSLAGSVTPSDQ-CPRAEVLRREDVKRRMVYLKILFNSKEVSRTVNRQLGA
DFRVHFGQ---IFNLQIFNWPESLLLQVYE-TVGHTSTVLLA-EVFLPVPETTVVTGRAP
ME-EVEFSSSQHVTLDHEGVGSGVPFSFEADGSNQLTLMT-----SGRVSHSVAWAVGDN
GTPLIP

ENSGT00510000046611_0_Linker_0_1 (967, 1210)

PLSQQNIGFRSALKRADAISSIGTSGLTDMKKLAKWAAESKLDPN-DPNNAPLM
QLISVATSGESYVPDFFRLEQLQQEFNFVTNEELNRSKRFRLLCLRSQEVPEFRNYKQIP
AYDREIMEKVFQDYEKRLRDKSVIETRDHIDTHRAVVAKYLQQVRESVVNRFLTAKHHIL
LTDLVVEDEVPNISSEGSGIWGL-SLFKLAEQKRPLRPRR-----KGRKKVTAQN-----
--LSDGDIK

PF00168 // ENSGT00510000046611_0_Domain_1 (1210, 1376)

LLVNICRAYDIPVRKPTASKAQQPSRSSRTLSEKRAASPSAH----SPDNA
LGQVLVRPFVEVSFQRTVCRTATAEGPNPSWNEELEFPF---RAPNGDYSTASLQSVKDE
VFINVFDEVLHDILEDDRERGSG-IHTRIERHWLGCVKIPFSTIYSQARIDGTFKIDIPP
VLLGYCKERSVTAERGLDSVRSLSEGSYLTLFITIEPQLVPGQPVREKLSG----MLT-K
FDSQEDEKLLQATEKFQAECALKFPNRQCFTTVIDLSGKTVFITRYLKPLNPPEELLNAY
PSNPQAIAELAARYVSLIPFLPDTASFTGVCDLWSTSD---QFLDLLAGDEEEHAVLLCN
YFLFLGKKAWLVMGNAIPEGPTVYVLTWEQNHYFIWNPCSGHFYGQFDTFCPLKSVSCLI
GPDNIWFNIQQYDSPLRINFDVTKPKLWKSFFSRS-LPYPGLSSVQPEELIYQRTDKAAA
AELQD--RIEKMLKEKIMDWRPRHLTRWNRHCTSTLRHFLPLLERSHGEDVEDDHRAELQ
RQLGDYRFSGFPLHLSYSEVKPLIEAVYSTGVHNIDVPNAEFALAVYIHPYPKNVLSVWI
YVASLIRNR

-------------------------FTGDDVD----AEVGRRK-------KNSKVQRKQ-
-KKKKPPTT-PPEKMVSDKFQDGGQP------E--------MVEEEPETKLLSLTARRGA
R----------SLPPIPSAS-RTGFAEFSMRERMREKLQAARSKAESALLRDAPTPRPRR
LHSPS-ERETETE--FGTEPSKEVGGTQQED-NTQSHSRFKLHDSARKIKSKPQPPPGFP
SAEEAYNFFTFNFDPEP---EGRTQV---KGGDKAHQEDQEG--E-EGTHAQERT---KK
MEEEELLNGKDAEDFLLGLASTAHDFVSVRAAEYESVHIRLEKEKEILFTPSRLT----V
PTYKKLPENV-QPR-FLEDEGLYIG-ARPEVARTNENIMENRLLIQEPGRKWFGDDGRIL
ALPSPIKPFPSRPSLATQEQSTKAELETLYKKAVKYVHS-RQRMIGSGDPP--GNFQLDI
-DISGLIF-SHHPCF-SREHVLASK----LAQLYDQYLA---------------------
----------RQQRNKTQFLTDKLQALRKAIQTGLNPEKPHQSLDTTQKTINEYKSEIRQ
TRKLRDAEQEKDRTLLKTIIKVWK-EMKSLREFQRFTNTPLKLVLRKEKVDQKADE----
----------DEYEAEIQAEI-HELLEEHMEEYTRKM-EEYRALHQQWKAWRKAQRAKKK
KK---KQTAEEHPE---EEEEVEEPFP-EEIKKPIPPELTDPAVIEQQVRERVAHSRRR

PF15625 // ENSGT00510000046611_0_Domain_0 (780, 967)

P
G-EPTLVPELSLAGNVTPNDQ-CPRVEVLRREDVRRRSVYLKVVFNSKEVSRTVSRPLGA
DFRVHFGQ---IFNLQIFNWPESLMLQVYE-TIGHSGTILLA-EVFLPIPETTIVTGRAP
IE-EVEFSSNQHVTLDHEGVGSGVPFSFEADGSNQLTLMT-----SGKVSHSVAWAVGEN
GIPLIP

ENSGT00510000046611_0_Linker_0_1 (967, 1210)

PLSQQNIGFRSVLKRADAISSIGTSGLTDIKKLAKWAAESKLDPN-DPNNAPLM
QLISVATSGESYVPDFFRLEQLQQEFNFVSEEELNRSKRFRLLRLRSEEVPEFRNYKQIP
VYDREIMEKVFQDYEKRLRDRNVIETKDHLDAHRATVAKYLQQVRESVVNRFLIAKHHFL
LTDLVVEEEVPNISSEGSGILGL-SLFKLAEQKRPLRPRR-----KGRKKVTAQN-----
--LCDGDIK

PF00168 // ENSGT00510000046611_0_Domain_1 (1210, 1375)

LLVNIIRAYDIPVRKPIASKFQQTSRSSRTFSEKQTASPNTHSPVHSTDYP
LDQVLVRPFVEVSFQRTICHTTTAEGPNPSWNEELELPF---RAPNGDYSTASLQAVKDD
VYINIFDEVLHDILEDDRERGSG-IHTRIERHWLGCVKIPFSTIYFQARIDGTFKIDIPP
VLLGYSKERNITMERTFDSARSLSEGSYITLFITIEPQLVPGEPIREKMSD----MLK-K
FDSQEDEKLLQATEKFQAECALRFPQRQCLTTVIDMRGKTVFITRFLKPLNPPQELLNVY
PNNPQATAELVARYVSLIPFLPDTVSFAGICDLWSTSD---QFLDLLAGDEEEHAVLLCN
YFLSLGKKAWLMMGNAIPEGPTAYVLTWEKNYYLIWNPCSGHCYGQFDTFCPLKSVGCLI
GPDNIWFNIQHHDSPLRINFDVTKPKLWKSFFSRS-LPYPGLSSVQPEELIYQRTDKVAA
AELQD--RIEKILKDKIMDWRPRHLTRWNRYCTSTLRHFLPLLERSQGEDIEDDHRAELL
KQLGDYRFSGFPLHMPYSEVKPLIEAVYSTGVHNIDVPNVEFALAVYIHPYPKNVLSVWI
YVASLVRNR

-----------MNPREEKVKIITEEFIENDED----ADMGRQK-------RNSKVRRQP-
-RKKQPPTA-LPKEMVSEESHLGNQP------E--------PVQEEPKTHLLSMTVRRGP
R----------SLPPIPSTS-RTGFAEFSMRGRMREKLQAARSKAESALLQEIPTPRPRR
LRSPS-KKELETE--FGTEPGKEVESTQQEI-DSRSYSRVKFRDSARKIKPKPQVPPGFP
SPEEAYNFFTFSFDPEPEESEEKP---KARHRAGTNQEEEEG--EEEEPPARGRG---KE
MDEEELLNGDDAEDFLLGLDHMADDFVAVRPADYESIHDRLQMETEMLFIPSRQT----V
PTYKKLPENV-QPR-FLEDEGLYTG-VRPEVARTNQNIMENRLLMQDPERRWFGDDGRIL
ALPNPIKPFPSRRPVLTQEQSIKAELETLYKKAVKYVHS-SQHMIRSGDHP--GNFQLDI
-DISGLIF-THHPCF-SREHVLAAK----LAQLYDQYLA---------------------
----------RHQRNKAKFLTDKLQALRNAVQTGVDPEKPHSSLDTIQKTINEYKSEIRQ
TRKFRDAEQEKDRTLLKTIIKVWK-EMKSLREFQRFTNTPLKLVLRKEKVDQKADE----
----------EAYEAEIQAEI-SELLEEHTEEYAQKV-EEYRTSLHQWKAWRKAQRAKKK
KR---KQAAEDHP-----NDEIEEPHPEEDLVKPTPPEPTDRAVIEHEVRERAAQSRRRP
W-

PF15625 // ENSGT00510000046611_0_Domain_0 (783, 967)

EPTLVPELSLAGSVTPSDQ-CPRAEVSRREDVKKRSVYLKVLFNNKEVSRTVSRPLGA
DFRVHFGQ---IFNLQIVNWPESLTLQVYE-TIGHSSPTLLA-EVFLPIPETTVVTGRAP
IE-EVEFSSNQHVTLDHEGVGSGVPFSFEADGSNQLILMT-----SGKVSHSVAWAIGEN
GIPLIP

ENSGT00510000046611_0_Linker_0_1 (967, 1210)

PLSQQNIGFRSALKRADAISSIGTSGLTDMKKLAKWAAESKLDPN-DPNNAPLM
QLISVATSGESYVPDFFRLEQLQQEFNFVSDQELNRSKRFRLLRLRSQEVPEFRNYKQVP
VYDREIMEKVFQDYEKRLRDRSVIETKEHIDTHRAIVAKYLQQVRESVINRFLIAKQYFL
LADMIVEEEVPNIS-----ILGL-SLFKLAEQKRPLRPRR-----KGRKKVTAQN-----
--LSDGDIK

PF00168 // ENSGT00510000046611_0_Domain_1 (1210, 1375)

LLVNIVRAYDIPVRKPAVSKFQQPSKSSRMFSEKRAASPSTHSPTHNADYP
LGQVLVRPFVEVSFQRTVCHTTTAEGPNPSWNEELELPF---KAPNGDYSTASLQSVKDI
VFINIFDEVLHDVLEDDRERGSG-IHTRIERHWLGCVKIPFSTIYFQARIDGTFKIDIPP
VLLGYNKERNMILERGFDSVRSLSEGSYITLFITIEPQLVPGESIRE------------K
FESQEDEKLLQATEKFQAECALKFPNRQCLTTVIDISGKTVFITRYLKPLNPPQELLNVY
PNNLQATAELVARYVSLIPFLPDTVSFGGICDLWSTSD---QFLDLLAGDEEEHAVLLCN
YFLSLGKKAWLLMGNAIPEGPTAYVLTWEQGHYLIWNPCSGHFYGQFDTFCPLKNVGCLI
GPDNIWFNIQRYDSPLRINFDVTKPKLWKSFFSRS-LPYPGLSSVQPEELIYQRSDKATA
AELQD--RIEKILKEKIMDWRPRHLTRWNRYCTSTLRHFLPLLEKSQGEDVEDDHRAELL
KQLGDYRFSGFPLHMPYSEVKPLIDAVYSTGVHNIDVPNVEFALAVYIHPYPKNVLSVWI
YVASLIRNR

-----------MNANDEKMKIISEDFTGDGVD----TEAGRRK-------KNSKVRRQQ-
-RKKKPPAS-PPEEMVSDKFQDGGQQ------E--------VVEEEPETNLLSLTARRGP
R----------SLPPIPSAS-RTGFAEFSMRERMREKLQAARSKAESALLRDVPTPRPRR
LRSPSREKETETE--FGTEPSTEVQDTQKED-DTKSYSRIKFSDSVRKIKSKPQLPPGFP
SVEEAYNFFTFNFDPEPEESEEKSPV---KGGERAHQEDQEG--E-EGTQAQERA---KK
TEEEELLNGKDAEDFLLGLDPTAHDFVAVRAAEYKSARIQLHKEKEILFTPSRLT----V
PTYKKLPENI-QPR-FLEDEGLYIG-ARPEVAHTNENIMENRLLIQEPGSKWFGDDGRIL
ALPSPIKPFPSRPSLSTREQSPKAGLETLYKKAEKYVHS-RQQMIGSGGPP--GNFQLDI
-DISGLIF-THHPCF-SREHVLASK----LAQLYDQYLA---------------------
----------RQQRNKTKFLTDKLQALRKAVQTSLNPEKPHQSLDTTQKTINEYKSEIRQ
TRKLRDAEQEKDRTLLKTIIKVWK-EMKSLREFQRFTNTPLKLVLRKEKVDLKLDE----
----------DAYEAEIQAEI-HELLEEHMEEYATKM-EEYRTSHQQWKAWRKAQRAKKK
KK---KQTTEEHLE---E-EEAEEPFPEEEVTKPIPPEPTDPAVIEQQVRERAAHSRRR

PF15625 // ENSGT00510000046611_0_Domain_0 (780, 967)

P
G-EPTLIPELSLAGNVTPNDQ-CPRVEVSRREDVRRRSVYLKVVFNSKEVSRTVSRPLGA
DFRVHFGQ---IFNLQIFNWPESLMLQVYE-TIGHSGTTLLA-EVFLPIPETTLVTGRAP
IE-EVEFSSTQHVTLDHEGVGSGVPFSFEADGSNQLTLMT-----SGKVSYSVAWAVGEN
GIPLIP

ENSGT00510000046611_0_Linker_0_1 (967, 1210)

PLSQQNIGFRSALRRADAISSIGTSGLTDMKKLAKWAAESKLDPN-DPNHAPLM
QLISVATSGESYVPDFFRLEQLQQEFNFVSEEELNRSKRFRLLHLRSQEVPEFRNYKQIP
AYDREIMEKVFQDYEKRLRDRNVIETKDHLDMHRATVAKYLQQVREAVVNRFLTAKHHFL
LTDLVVEEEVPNISSEGSGILGL-SLFKLAEQKRPLRPRR-----KGRKKVTAQN-----
--LSDGDIK

PF00168 // ENSGT00510000046611_0_Domain_1 (1210, 1375)

LLVNIIRAYDIPVRKPVVSKFQQPSRSSRTFSEKQTASPSTHSPLHNADYP
LGQVLVRPFVEVSFQRTICHTTTAEGPNPSWNEELELPF---RAPNGDYSTASLQSVKDD
VYINIFDEVLYDILEDDRERGSG-IHTRIERHWLGCVKIPFSTIYFQARIDGTFKIDIPP
VLLGYSKERNIIMERAFDSARSLSEGSYITLFITIEPQLVPGEPMREKMSD----MLK-K
FDTQEDEKLLQATEKFQAECALKFPQRQCLTTVTDMTGKTVFITRYLKPLNPPQELLHVY
PNNPQAAAELVARYVSLIPFLPDSVSFAGVCDLWSTSD---QFLDLLAGDEEEHAVLLCN
YFLFLGKKAWLVMGSAIPEGPTAYVLTWEKNYYLIWNPCSGHCYGQFDAFCPLKSVGCLI
GPDNIWFNIQHHDSPLRINFDVTKPKLWKSFFSRS-LPYPGLSSVQPEELIYQHTDKAVA
AELQD--RIEKILKEKIMDWRPRHLTRWNRYCTSTLRHFLPLLERSQGEDIEDDHRAELL
KQLGDYRFSGFPLHMPYSEVKPLVEAVYSTGVHNIDLPNVEFALAVYIHPYPKNVLSVWI
YVASLVRNR

-----------MNPREEKVKIITEEFIENDED----ANVGKRK-------KNSKVQRQP-
-RKKQPPTT-GPDKMVSEESHLGNQQ------E--------PAQDKPQTRLLSVTARRGP
R----------SLPPIPSAS-RIGFAEFSMRERMREKLQAARSKAESALLQEIPTPRPRR
LRSPS-VKELETE--FGTESGKEVGSTQQED-DSQSYSRVKFHVSARKIKSKPQVPPGFP
SAEEAYNFFTFTFDPEPEEAEEKP---K--HQDGTNQEEEEG--E-EEPPAQEGA---NR
MDEEELPHGKDAENFLLGLDHTANEFLAVRPADYESVHVRLQREKEMLFIPSRLT----V
PTYKKLPENV-QPR-FLEDEGLYIG-ERPEVARTNQNIMENRLLTQEPGRRWFGDDGRIL
ALPNPIKPFPSRPPVLTQEQSIKTELETLYKKAVKYVHR-SQHMIGSGDPS--GNFQLDI
-DISGLIF-THHPCF-SREHVLAAK----LAQLYDQYLA---------------------
----------RHQRNKAKFLTDKLQALRNAVQTGLNPEKPHQSLDMIQKTINEYKSEIRQ
TRKLRDAEQERDRTLLKTIIKVWK-EMKSLREFQRFTNTPLKLVLRKEKVDQKADE----
----------EAYEAEIQAEI-SELLEEHTEEYEQKM-EEYRTSYQQWKAWKKAQVCKHR
PDQAGSGRAEEHP-----EEETEEPYPEEDPVKPTPPEPTDQAAIEQQVRERAAQSRRR

PF15625 // ENSGT00510000046611_0_Domain_0 (780, 967)

P
G-EPTLLPELSLAGSVTPNDQ-CPRAEVWRREDVKRRSVYLKVLFNNKEVSRTVSRQLGT
DFRVHFGQ---IFNLQIFNWPESLTLQVYE-TVGHSSPTLLA-EVFLPIPETTVVTGRAP
IE-EVEFSSNQHVTLDHEGVGSGVPFSFEADGSNQLILMT-----SGKVSHSVAWAVGEN
GIPLIP

ENSGT00510000046611_0_Linker_0_1 (967, 1209)

PLSQQNIGFRSALKRADAISSIGTSGVTDMKKLAKWAAESKLDPN-DPNNGPLM
QLISVATSGESYVPDFFRLEQLQQEFNFVSDEELNRSKRFRLLHLRSQQVPEFRNYKQIP
IYDREIMEKVFQDYEKRLRDRNVIETKDHIDTHRAVVAKYLQQVRESVINRFLIAKHHFL
LADLVVEEEVPNIS-----ILGL-NLFKLAEQKRPLRPRR-----KGRKKVTAQN-----
--LSDGDI

PF00168 // ENSGT00510000046611_0_Domain_1 (1209, 1375)

KLLVNIIRAYDLPVRKPTASKFQQPSRSSRTFREKHAASPDTRSPTHSADYP
LGQVLVRPFVEVSFQRTICHTTTAEGPNPSWNEELELPF---RAPNGDYSTASLQSVKDV
VFINIFDEVLYDVLEDDRERGNG-IHTRIERHWLGCVKIPFSTIYFQARIDGTFKIDIPP
VLLGYSKEQNMIIERDFDSVRSLSEGSYITLFITIEPQLVPGESVRE------------K
VTVRRHH-----------------------------------------------------
-----------------INFWPGAV---SMYVFFSFRQ---QFLDLLAGDEEEHAVLLCN
YFLFLGKKAWLVIGNAIPEGPTAYVLTWEKSHYFIWNPCSGHFYGQFDTFCPLKNVGCLI
GPDNIWFNIQQYDSPLRINFDVTKPKLWKSFFSRS-LPYPGLSSIQPEELIYQNTDKVAA
AELQDS-RIEKILKEKIMDWRPRHLTRWNRYCTSTLRHFLPLLESSQGEDVEDEHRAELL
KQLGDYRFSGFPLHMPYSELKPLIDAVYSTGVHNIDVPNVEFALAVYIHPYPKNVLSVWI
YVASLIRNR

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------PGKEVETTQQED-DSQSYSRVKFR---------SCVPPGFP
SAEEAYNFFTFNFNPEPEESEEKP---KAKHRDGSHQEEEDR--EEEESPTQEGG---DE
TDEEELLSGKDAEDFLLGLDPAAGDFVAVRPADYESVHVRLQKEREMLFVPSRQT----V
PTYKKLPENV-QPR-FLEDEGLYIG-ERLEMAHSHQNIMENRLLTQEPGRRWFGDDGRIL
AMPNPIKPFPSRPPVLTQEQSIKAELETLYKKAVKYVHS-SQHMIGSGDPP--GNFQLDI
-DISGLIF-THHPCF-SREHVLAAK----LAQLYDQYLA---------------------
----------RHQRNKAKFLTDKLQALRNAVHTGLNQEKPHQSLDAIKKTIKEYKSEIRQ
TRKLRDAEQEKDRTLLKTIIKVWK-EMKSLREFQRFTNTPLKLVLRKEKVDQKADE----
----------DAYEAEIQAEI-SELLEEHAEEYEWMM-EEYRMSYQQWKARKKAQRAKKK
KR---KPTAEERS-----DEETEEPCPEEELVKPTPPEPADRAVIEQQVRERAAHSRRR

PF15625 // ENSGT00510000046611_0_Domain_0 (780, 967)

P
G-EPTLVPELSLAGSLTPNDQ-CPRVEVLRREDVKRRSVYLKVLFNNKEVSRTVSRQLGA
DFRVHFGQ---IFNLQIFNWPESLTLQVYE-TVGHGSPTLLA-EVFLPIPETTIVTGRAP
VE-EVEFSSNQHVTLDHEGVGSGVPFTFEADGSNQLILMT-----SGKVSHSVAWAIGEN
GIPLIP

ENSGT00510000046611_0_Linker_0_1 (967, 1210)

PLSQQNIGFRSALKRADAISSIGTSGLTDMKKLAKWAAESKLDPN-DPNNAPLM
QLISVATSGESYVPDFFRLEQLQQEFNFVSDEELNRSKRFRLLHLRNQEVPEFRNYKQIP
VYDREIMEKVFQDYEKRLQDRNVIETKEHIDTHRAIVAKYLQQVRESVINRFLVAKHHFL
LADLVVEEEVPNIS-----ILGL-SLFKLAEQKRPLRPRR-----KGRKKVTAQN-----
--LSDGDIK

PF00168 // ENSGT00510000046611_0_Domain_1 (1210, 1375)

LLVNIIRAYDIPVRKPTASKFQQPSRSSRTFSEKHAAPLSTNSPTHSADYP
LGQVLVRPFVEVSFQRTICHTTTAEGPNPSWNEELELPF---RAPNGDYSTASLQSVKDD
VFINIFDEVLYDVLEDDRERGSG-IHTRIERHWLGCVKIPFSTIYFQARIDGTFKIDIPP
VLLGYSKERNMILERGFDSVRSLSEGSYITLFITIEPQLVPGQSVRE------------K
FDSQEDEKLLQATEKFQAECALKFPNRQCLTTVIDISGKTVFITRYLKPLNPPQELLDVY
PNNPQATAELVARYVSLIPFLPDSVSFAGICDLWSTSD---QFLDLLAGDEEEHAVLLCN
YFLSLGKKVWLVMGNAIPEGSTAYVLTWEQTHYLIWNPCSGHFYGQFDTFCPLKSVGCLI
GPDNIWLNIQQYDSPLRINFDVTKPKLWKPFFSRS-LPYPGLSSVQPEELIYQHTDKAAA
AELQD--RIEKILKEKIMDWRPRHLTRWNRYCTSTLRHFLPLLERSQGEDVEDDHRAELL
KQLGDYRFSGFPLHMPYSEVKPLIDAVYSTGVHNIDVPNVEFALAVYIHPYPKNVLSVWI
YVASLIRNR

--------------------MLTKEFTENDED----AQVRRQK-------KKSRAQRQQ-
-RKKQPRTP-GPEEMVSENCHVGP------PLE--------PGEEKPDTHLLSTTARRGP
R----------SLPPVPSTS-RTGFAEFSMRERMREKLQAARSKAESALLQEIPTPRPRR
LRSPS-ERESETE--FGTEPSKEIQGTQQED-DLKSYTRVKFHDSVRKLKSKSQAPPGFP
SAEEAYNFFIFNFDPGPEEQEEKP---TVICRDGANQEEEEG--EEE-----------AR
RKEREFQNGKDAEDFLLGLDPAAHNFVTVRAAEYESTHIRLQKEKEVLFVPSRLT----V
PTYKKLPENV-QPR-FLEDEGLYIG-ARPEVARNNQNIMENRLLMQESGRKWFGDDGRVL
ALPSPIKPSPSRPPQFTQELSNKAELETLYKKATKYIHR-HQHMIGSGDPP--GNFQLDI
-DISGLIF-THHPCF-SREHVLASK----LAQLYDQYLA---------------------
----------RHQRNKAKFLTDKLQALRNAVQTGLNPEKSHHSLDTTQTNINEYKSEIRQ
TRKLRDAEQEKDRTLLKNIIKVWK-EMKSLREFQRFTNTPLKLVLRKEKVDQKADE----
----------EAYEAEIQAEI-NELLEEHAEEYAQKM-EEYKTSHQQWKAWKKAQRAKKK
KN---KQAAEENP-----DEEGGEPFPEEEPVKPIPPEPTDTAIIEQQVRERAVHSRRR

PF15625 // ENSGT00510000046611_0_Domain_0 (780, 967)

P
G-EPKLVPELTLAGNTTPNEQ-CPRVEVLRREDVKRRSVYLKVLFNNKEVSRTVSRQLGA
DFRVHFGQ---IFNLQIFNWPESLTLQVYE-TVGHSSTTLLA-EVFLPIPETTLVTGRAP
IE-EVEFSSSQHVTLDHEGVGSGVPFSFEADGSNQLILMT-----SGKVSHSVAWAIGEN
GIPLIP

ENSGT00510000046611_0_Linker_0_1 (967, 1210)

PLSQQNIGFRSALKRADAISSIGTSGLTDMKKLAKWAAESKLDPN-DPNNAPLM
QLISIATSGESYIPNFFRIEQLQQEFNFVSDEELSRSKRFRLLSLRSQEVPEFRNYKQIP
IYDREIMEKVFQDYEKRLRDRNVIETKDHLDAHRATVAKYLQQVRESVVNRFLLAKHHFL
LTDLVAEEEVPNIS-----ILGL-SLFKLAEQKRPLKPRR-----KGRKKVTAQN-----
--LSDGDIK

PF00168 // ENSGT00510000046611_0_Domain_1 (1210, 1375)

LLVNIIRAYDIPVRKPIVSKFQQPSRSSRTFREPHAASPSAHSPAHSADYP
LSQVLVRPFVEVSFQRTICHTTTAEGPNPSWNEELELPF---RAPNEDYSTASLQSVKDD
VYINIFDEVLYDVLEDDRERGSG-IHTRIERHWLGCVKIPFSTIYFQTRIDGTFKIDIPP
VLLGYSKEHNMIMERGFDYARSLSEGSYITLFITIEPQLVPAEPVREKMSD----MLK-K
FDSQEDEKLLQATEKFQAECALKFPHRQCLTTVIDISGKTVFITRYLKPLNPPPELLNVY
PNNSQATTELVARYVSLIPFLPDSVSFAGICDLWSTSD---QFLDLLAGDEEEHAVLLCN
YFLSLGKKAWLVMGNAIPEGPTAYVLSREKNHYLIWNPCSGHCYGQYDTFCPLKTVGCLI
GPDNIWFNIQEHDSPLRINFDVTKPKLWKSFFSRS-LPYPGLSSVQPEELIYQRTDKAAV
AELQD--RIEKILKEKIMDWRPRHLTRWNRYCTSTLRHFLPLLESSQGDDVEEEHRAELL
KQLGDYRFSGFPLHMPYSEVKPLIEAVYSTGVHNIDVPNVEFALAVYIHPYPKNVLSVWI
YVASLIRNR