Query Results 

MDGSGAGL--------------------------------SAGSGSDGDRRDGTECGGFS
DQLDWSQSHKDLMVMIQEIKKCLPEEKRSSSKPSTISALNYALRCVQQVRANNEFFQALN
D-RRMFQTDVMTYSTEELVTLASERTPKNN----------------DTFVAVFS-LLSGR
IVHISEQAASILNYKKQVLESSRFVELLAPQDASVFYAHTDQSHLPLWNTESQT-ASLYE
YAQ-VKSFFCRIRGGKDQ-EQEMHWYPFRITPYLVHVCTSVHVD----AESCCLALAEKI
HSGYE------APRIPMDKRIFTTTHTPGCVF

PF08447 // ENSGT00510000046467_0_Domain_0 (333, 421)

LEIDDRAVPLLGYLPQDLIGTSILMYLH
PEDRPLMIAIHRK-ILKFAGQPPFEYLPIRFCTQNGDYVILDTSWSSFVNPWSRKVAFII

ENSGT00510000046467_0_Linker_0_1 (421, 1197)

GRHKVRTSPLNEDVFATRSQEASSVEKEIKELQGQIYKLLLQPVHSNV--SSGYGSLGSS
GSYEHYISVASSSDSNGNCAE------ETQEPMTLQQVCADVNRIKNLGQQLYIASRSKP
QNGN-DQPMSSEMLE-------------GKRHNASCFLPTLGSDSTEELGHALYDDLKKT
PHVPSYQQINCVDSIIR--YLESCSIPLLKRKCKSSTNTSSSSSEGDKKNQQRLQEIKAL
GGNGKDPGNYTADPSSVNSRTPVFADQEEVLKKQTNEGIVGAPLPDLTLSNRSPSVVSAT
SQCSYSSTIVHVPHPESEVTTVENTP------VGNEHIELP-PPNA----QNLVAVTEGL
KPVGLTKETLSAHTQKEEQNYVDKFRRRILLSPLRTYLQQDGRSN---IGRFCDQG-SSP
SKEMAQASCKNGKKGKFKHQKPQRRSSDRRSCSKNRN--GL---PCEKRRIQKQSLSPSE
VSHLSSSSMNFFPPVG-YP---VYSDALSSFPA-----SSVGEELAICSSKPEPTSLSQL
C-CGAPSFPGLSSPNIGMFMAVFFHSFPIYTQVPQYA---FLPSTQNVYLPS-YPCTAVP
PAPPPPAPSP------IAPNSVDQSCPASSATSTEEQLEGQHGRALQL-SSSRSSSPLQL
NLLQEELPESAEPSLSTDVKA-CAEAN--CD-----------------------------
--------------------------------------------NSLEDSGNSASS

PF12114 // ENSGT00510000046467_0_Domain_1 (1197, 1386)

HCAS
SECTDRLLHEDSQSGTGSAASGSGLALSSSLGS----------------HSCETSGGGTA
DSGKNSNCFASNDSSE-TSKAE-TDQEA-KEKETPHKSKYESAWVMMDHTPEQVLMTYQM
PNRVKE--EVLKEDMEKLIVMRKQQPWFSDRQKRELAEVHTWIRTQTVPLQINTQGCVTC
DIREATCESA-------MADD--NMENKGKPLPVLEH---------------

------LDSRGSEPRE--PQAC----C-----SEALGKGQEEVWSEKSQLQSPQVESTNS
EQQDRNRVSEELVMVVQEMKKYFPSGR--HSKPSTLDALNYALRCVHSVQASSEFFQILS
Q-SGTLQTDATVYSLEELATLASGYTSKNT----------------DTFVAVFS-FLSGR
LVHVSEQATLILNCKKDFLESSHFMELLAPQDVRVFCAHTAHTQLPLWNNWTQRAS-QYE
FAP-VKSFFCRIRGGKDA-EQEKHYYPFRIIPYLIHVHRAAQPE----PEPCCLTLVEKI
HSGYE------APRIPVDKRI

PF14598 // ENSGT00510000046467_0_Domain_0 (322, 425)

FTTTHTPGCVFLEIDERAVPLLGYLPQDLMGRSVLTYLH
PEDRSLMLTVHQK-VLKYAGHPPFEHSPIRFCTQNGDYIILDSSWSSFVNPWSRKVSFII
GRHK

ENSGT00510000046467_0_Linker_0_1 (425, 1074)

VRMSPLNEDVFATRIKKMNSNDKDVTELQEQIHKLLLQPVPASA--SSGFGSLGSG
DSQEPRASLASSRESGGPRGE-----AARRAPTALQRVCASVNKMKKLGGQLHIESAAAR
SV-KRFNSSVPQPEACSEQ-------------KASSPLQTLKNNS---VHMESCEGWRKD
QHSPSYQQINCIDSVIR--YLKSYNIPALKRKCISCTNTTSSSSEEDGQNH-KAHHAQAL
Q---------------GNTN-ALLTNLEIPTAWQSTHATEGTP---RTLAPAALSLGSGM
SQCSYSSTMVLAPPPESAEVTPTEDAA--------PVCEPW-TLST----SPAPLMSEEF
KHIGLTKAVLSAHTQKEEQNYVDKLREKIFLSPYRSCLQQESRS--R-AKHLYVQG-DCA
GKQTRSTGCKKGKSKQKKLPVLSDSRGT------QDTFCPH----FGGESESRQPWGPAL
SSCLQAPGLSF-PAAMMVPSLAPY--FVPALRIP-ALPSVQREPGASLTTLD-YLLKPPL
L-NGLHSFPALPSPSSDTVMTTFLPDPTGCPLLSP----SFC--------PYAFLGAAGS
SGTPP-FVSA------VAP-HLEQLSSVLSQRQAEGRWEMPHG-EHHC-INSR

PF12114 // ENSGT00510000046467_0_Domain_1 (1074, 1386)

SSSPLQL
NLLQEDMLRSCESSDQVRGDI-YQKLNMEGV-------------LGRSGSKKNPFT----
--A------------SELSMALLPE-----------------------------------
----------ESPSG---------------------------------------AGSTAS
GSSDSSIYLASSDYSSEITSNGQQFQGV-QGKETFPGLAEESMWRMIKQTPECILMTYQV
PERVTE--AVLREDLEKLASMQGQQPWFSRGQRQELASVHSWIQSQTVPQGIDIQDCVTC
ESKESVRV-FAESCGHTPA-----ANSS------------------------

----------RRAPPGPRGQAA----G-----GAALCGE-AETRSPGFRLQRGHVERSHS
PRQDRNRVSEELIMVVQEMKKCFPSER--HRKPSTLDALNYALRCVHSVQANSEFFSVLH
Q-EGASVREETLCNLEELAALASEHTSKNT----------------DTFVAVFS-FLSGR
LVHISAQAASILNCKKDFLETFHFVDLLGPQDVRVFYAHTARAQLPSWNNWTQRAS-QYE
YAP-VKSFFCRIRGGEDR-EREKYYSPFRIIPYLIHVHSSAQPE----SEPCCLTLVEKI
HSGYE------APRIPVDKRIFTTTHTPGCVF

PF08447 // ENSGT00510000046467_0_Domain_0 (333, 421)

LEVDERAVPLLGYLPQDLIGTSILTHLH
PEDRSLMVAIHQK-VLKYAGHSPFEHLPVRFCTQNGDYVILDSSWSSFVNPWSRKISFII
GRHKVRT-----------------------------------------------------
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MEPRGDLEMPRGEPPGPGGRGA----E-----DKALDEESGERWSPEFHLQRKLAESSHS
EQQDRNRVSEELIMVVQEMKKYFPSER--RNKPSTLDALNYALRCVHSVQANGEFFQILS
Q-NGAPQADVTMYSLEELATIASEHTSKNT----------------DTFVAVFS-FLSGR
LVHISEQAALILNRKKDVLASSHFVDLLAPQDVRVFYAHTARAQLPFWNNWTRR-APRYE
CAP-VKPFFCRIRGGEDR-KQEKRHSPFRIIPYLIYVHRPGQPELE--SEPCCLTVVEKI
HSGYE------APRIPVNKRIFTTTHTPGCVF

PF08447 // ENSGT00510000046467_0_Domain_0 (333, 421)

LEVDERAVPLLGYLPQDLIGTSILSYLH
PEDRSLMVAIHQK-VLKYAGHPPFEHSPIRFCTQNGDYIILDSSWSSFVNPWSRKVSFII

ENSGT00510000046467_0_Linker_0_1 (421, 1183)

GRHKVRTSPLNEDVFATEIKKMNNNDKDVTELQEQIYKLLLQPVHVSV--SSGYGSLGSS
GSQEQLVSIASSSEASGHCVE-----ETKAEQMTLQQVYASVNKIKNLGQQLYIESMAKS
SF-KPVTGTRTERNGGGESAN-----DDGDYKTFTSFHQTLKNNS---VYTEPYEDLRND
EHSPSYQQINCIDSVIR--YLKSYNIPALKRKCISCTNTTSSSSEEDKQNH-KADDVQAL
Q---------------AGLQIPTIPKSEMPTNGRSIDAGGGAP---QILSTAVLSLGSGI
SQCGYSSTIVHVP-PETA-----RDAT--------LVCEPW-TLNM----QPAPLTSEEF
KHVGLTAAVLSAHTQKEEQNYVDKFREKILSSPYSSYLQQESRS--K-AKYSYFQG-DYT
SKQTQLAGCRKGKHKRKKLPEPPDSSSS------NAGSGP-----HRGARQNAQPCCPST
ASSPHTSGPTF-PPAAMVPSQAPY--LIPAFPLP-AATCPGREYATPGTAPE-GLHGQPL
S-KGLQPYPAFSSPYLDTFMTVFLPDPHVCPLLSP----SFF--------PCPFLGATAS
SAISPSMSSA------MTP-AVDPPASVTNRTREEEKWEAQSE-GHPF-ITSRSSSPLQL
NLLQEEMPRSSESPDQMRRST-CPQAEY-CV-------------TGNSGSESSPAT----
--T------------GALSTGPPPRENPSHPTASTLSMGSPP

PF12114 // ENSGT00510000046467_0_Domain_1 (1183, 1390)

SGTPSH---------PTA
SVLSAGSPPSESPSGTGSA---------------------------------------AS
GSSDSSIYFTSSVYS-KITQNEQQSQDV-QKKETFPNVAEESIWRMIRQTPECVLMTYQV
PERVKE--VVLKEDLEKLETMRQQQPQFSHGQKEELAKVYNWIQSQTVPQEIDIQACVTC
KNEDSADG-AATSCSQALA-----EDSS------------------------

--------MPRGEAPGPGRRGA----E-----DEALGEESGEPCSPEFHLQRKLADSSHS
EQQDRNRVSEELTMVVQEMKKYFPSER--RNKASTLDALNYALRCVHSVQANSEFFQILS
Q-NGAPQADVTMYSLEELATIASEHTSKNT----------------DTFVAVFS-FLSGR
LVHISEQAALILNRKKDVLASSHFVDLLAPQDVRVFYAHTARAHLPFWNNWTQRAAPRYE
CAP-VKPFFCRIRGGEDR-KQEKCHSPFRIIPYLIHVHHPAQPESE--SEPCCLTVVEKI
HSGYE------APRIPVNKRIFTTTHTPGCVF

PF08447 // ENSGT00510000046467_0_Domain_0 (333, 421)

LEVDERAVPLLGYLPQDLIGTSILSYLH
PEDRSLMVAIHQK-VLKYAGHPPFEHSPIRFCTQNGDYIILDSSWSSFVNPWSRKVSFII

ENSGT00510000046467_0_Linker_0_1 (421, 1259)

GRHKVRTSPLNEDVFATKIKKMNNNDKDITELQEQIYKLLLQPVHVSV--SSGYGSLGSS
GSQEQLVSIASSSEASGHCVE-----ETKAEQMTLQQVYASVNKIKNLGQQLYIESMTKS
SF-KPVTGTRTEPNGGGESAN-----GGGECKTFTSFHQTLKNNS---VYTEPCEDLRND
EHSPSYQQINCIDSVIR--YLKSYNIPALKRKCISCTNTTSSSSEEDRQNH-KADDVQTL
Q---------------AGLQIPAIPKSEMPTNGQSVDTG-GAP---QILSTAMLSLGSGI
SQCSYSSTIVHVPPPETA-----RDAT--------LFCEPW-TLNM----QPAPLTSEEF
KHVGLTAAVLSAHTQKEEQNYVDKFREKILSSPYSSYLQQESRS--K-AKYSYFQG-DST
SKQTWSAGCRKGKHKRKKLPEPPDSSSS------NWGSGP-----RRGAHQNAQPCCPSA
ASSPHTSSLTF-PPAAMVPSQAPY--LVPAFPLP-AATSPGREYAAPGTAPE-GLHGPPL
S-EGLQPYPAFPFPYLDTFMTVFLPDPPVCPLLSP----SFF--------PCPFLGATAS
SVVSPSMSSA------MSP-TLNPPPSVTNQRREEEKWEAQSE-GHPF-ITSRSSSPLQL
NLLQEEMPRPSESADQMRRNT-CPQAEYQCV-------------TGNNGSESSPAT----
--T------------GALSTGSPPRENPSHPTASTLSMGLPPSRLHPI---------LL-
---------------------------------------PVFS--------HCSLKLL

PF12114 // ENSGT00510000046467_0_Domain_1 (1259, 1390)

GS
RSSDSSIYFTSSVYSSKISPNGQQSQDV-QKKETFPDVTEEPIWRMIRQTPERNSTTL--
--EVKE--VVLKEDLEKLESMRQQQPQFSQGQKEELAKMYKWIQSQTITQEIDIQACVTC
ENEDSADG-AATSCDQVLA-----EDSS------------------------

MEPRGDLETPRGEPPGTGGRGA----E-----DEALGEESGERWSPEFHLQRKLAESSHS
EQQDRNRVSEELIMVVQEMKKYFPSER--RNKPSTLDALNYALRCVHSVQANGEFFQILS
Q-NGAPQADVTMYSLEELATIASEHTSKNT----------------DTFVAVFS-FLSGR
LVHVSEQAALILNRKKDVLASSHFVDLLAPQDVRVFYAHTARAQLPFWNNWTQR-APRYE
CAP-VKPFFCRIRGGEDR-KQEKRHSPFRIIPYLIYVHRPGQPESE--SEPCCLTVVEKI
HSGYE------APRIPVNKRIFTTTHTPGCVF

PF08447 // ENSGT00510000046467_0_Domain_0 (333, 421)

LEVDERAVPLLGYLPQDLIGTSILSYLH
PEDRSLMVAIHQK-VLKYAGHPPFEHSPIRFCTQNGDYIILDSSWSSFVNPWSRKVSFII

ENSGT00510000046467_0_Linker_0_1 (421, 1187)

GRHKVRTSPLNEDVFATKIKKTNNNDKDVTELQEQIYKLLLQPVHVSV--SSGYGSLGSS
GSQEQLVSIASSSEASGHCVE-----ETKAEQMTLQQVYASVNKIKNLGQQLYIESMTKS
SF-KPVTGTRTELNGGGESAN-----DGGEYKTFTSFHQTLKNNS---VYTEPYEDLRND
EHSPSYQQINCIDSVIR--YLKSYNIPALKRKCISCTNTTSSSSEEDKQNH-KADDVEAL
Q---------------AGLQISTIPKSEMPTNGPSIDAGGGAP---QILSTAVLSLGSGI
SQCGYSSTIVHVP-PETA-----RDAT--------LVCEPW-TLNM----QPAPLTSEEF
KHVGLTAAVLSAHTQKEEQNYVDKFREKILSSPYSSYLQQESRS--K-AKYSYFQG-DYT
SKQTQLAGCRKGKHKRKKLPEPPDSNSS------NAGSGP-----HRGARQNAQPCCPST
ASSLHTLGPTF-PPAAMVPSQAPY--LVPAFPLP-AATCPGREYAVPGTVPE-GLHGPPL
S-KDLQPYPAFPSPYLDTFMTVFLPDPPVCPLLSP----SFF--------PCPFLGATAS
SAISPSMSSA------MTP-TLDPPASVTNQRREEEKWEAQSE-GHPF-ITSRSSSPLQL
NLLQEEMPRRSESPDQMRRNT-CPQAEY-CV-------------AGNSSSESSPAT----
--T------------GALSMGSPPRENPSHPTASTLSMGSPPSRTP

PF12114 // ENSGT00510000046467_0_Domain_1 (1187, 1388)

SH---------PTA
SVLSTGSPPCESLSGTGSA---------------------------------------AS
GSSDSSIYFTSSVYS-KISQNGQQSQDV-QKKETFPNDAEESIWRMIRQTPECVLMTYQV
PERVKE--VVLKEDLEKLESMRQQQPQFSHGQKEELAKVYNWIQSQTVPQEINIQACVTC
ENEDSADG-AATSCGQALA-----EDSS------------------------

MEPRGDLEMPRGEPPGPGGRGA----E-----DKALDEESGERWSPEFHLQRKLAESSHS
EQQDRNRVSEELIMVVQEMKKYFPSER--RNKPSTLDALNYALRCVHSVQANGEFFQILS
Q-NGAPQADVTMYSLEELATIASEHTSKNT----------------DTFVAVFS-FLSGR
LVHISEQAALILNRKKDVLASSHFVDLLAPQDVRVFYAHTARAQLPFWNNWTQR-APRYE
CAP-VKPFFCRIRGGEDR-KQEKRHSPFRIIPYLIYVHRPGQPESE--SEPCCLTVVEKI
HSGYE------APRIPVNKRIFTTTHTPGCVF

PF08447 // ENSGT00510000046467_0_Domain_0 (333, 421)

LEVDERAVPLLGYLPQDLIGTSILSYLH
PEDRSLMVAIHQK-VLKYAGHPPFEHSPIRFCTQNGDYIILDSSWSSFVNPWSRKVSFII

ENSGT00510000046467_0_Linker_0_1 (421, 1183)

GRHKVRTSPLNEDVFATEIKKMNNNDKDVTELQEQIYKLLLQPVHVSV--SSGYGSLGSS
GSQEQLVSIASSSEASGHCVE-----ETKAEQMTLQQVYASVNKIKNLGQQLYIESMTKS
SF-KPVTGTRTERNGGGESAN-----DDGEYKTFTSFHQTLKNNS---VYTEPYEDLRND
EHSPSYQQINCIDSVIR--YLKSYNIPALKRKCISCTNTTSSSSEEDKQNH-KADNVQAL
Q---------------AGLQIPTIPKSEMPTNGRSIDAGGGAP---QILSTAVLSLGSGI
SQCGYSSTIVHVP-PETA-----RDAT--------LVCEPW-TLNM----QPAPLTSEEF
KHVGLTAAVLSAHTQKEEQNYVDKFREKILSSPYSSYLQQESRS--K-AKYSYFQG-DYT
SKQTQLAGCRKGKHKRKKLPEPPDSSSS------NAGSGP-----HRGARQNAQPCCPST
ASSPHTSGPTF-PPAAVVPSQAPY--LIPAFPLP-AATCPGREYATPGTAPE-GLHGQPL
S-KGLQPYPAFSSPYLDTFMTVFLPDPHVCPLLSP----SFF--------PCPFLGATAS
SAISPSMSSA------MTP-AVDPPASVTNRTREEEKWEAQSE-GHPF-ITSRSSSPLQL
NLLQEEMPRSSESPDQMRRNT-CPQAEYQCV-------------TGNSGSESSPAT----
--T------------GALSTGPPPRENPSHPTASTLSMGSPP

PF12114 // ENSGT00510000046467_0_Domain_1 (1183, 1390)

SGTPSH---------PTA
SVLSAGSPPSESPSGTGSA---------------------------------------AS
GSSDSSIYFTSSVYS-KITQNEQQSQDV-QKKETFPNVAEESIWRMIRQTPECVLMTYQV
PERVKE--VVLKEDLEKLETMRQQQPQFSHGQKEELAKVYNWIQSQTVPQEIDIQACVTC
KNEDSADG-AATSCSQALA-----EDSS------------------------

-------------------RAA----E-----DEAQGEDSGERWSPEFHLQRKLADPSHS
EQQDRNRVSEELIMVVQEMKKYFPSER--RNKPSTLDALNYALRCVHSVQANSEFFQILS
Q-NGAPQADVTMYSLEELATIASEHTSKNT----------------DTFVAVFS-FLSGR
LVHISEQASLILNRKKDVLASSHFVDLLAPQDVRVFYAHTARAQLPFWNNWTQRAAPRYE
CAP-VKPFFCRIRGGEDR-EQEKRPSPFRIIPYLIHVHHPAQPESE--SEPCCLTVVEKI
HSGYE------GKSYINYRNYLTSVTYATCV-

PF08447 // ENSGT00510000046467_0_Domain_0 (333, 421)

VYLYPRAVPLLGYLPQDLIGTSILTYLH
PEDRSLMVAIHQK-VLKYAGHPPFEHSPIRFCTQNGDYIILDSSWSSFVNPWTRKVSFII

ENSGT00510000046467_0_Linker_0_1 (421, 1184)

GRHKVRTSPLNEDVFATKIKKMNNNDKDITELQEQIYKLLLQPVHMSV--SSGYGSLGSS
GSQEQLVSMASSSEASGQCLE-----ETKAEQMTLQQVYASVNKIKNRGQQLYIESRTKS
SI-KPVTGRCTEPNGGGE-------------SACTSFHQTMKNNS---MYTEPHEDLRND
EHSPSYQQINCIDSVIR--YLKSYNIPALKRKCISCTNTTSSSSEEDKQNH-KADDIQAL
Q---------------AGLQIPAIPKPEMPTNGRSTDTGGGAP---QILSTTVLSLGSGM
SQCGYSSTIVHVPPPETA-----RDAT--------LMCEPW-TLNM----RPAPLTSEEF
KHVGLTAAVLSAHTQKEEQNYVDKFREKILSSPYSSYLQQESRS--K-AKYSYFQG-DST
SKQTRSAGCRKGKHKRKKLPKPPDSSSS------NAGSGP-----LRGAHLNAQPCCPSA
ASSLHSSGPTF-PPAAMVPSQAPY--LVPAYPLP-AVTCPGREYAAPGTTSE-VLPGPSS
S-KDQQTCPAFPSPYLDTFMTVFLPNPSVCPLLS----------------PCPFLGVTAS
SAISPSM-SA------MTP-HLDPPP-VTNQRRGEEKWEAQSE-GHPF-ISSRSSSPLQL
NLLQEEMPRPSESPDEIRRNM-CPQAAYQCV-------------IGNSGSESNPAT----
--T------------PALSTGSPPRETPSHPTASALSPGSPPR

PF12114 // ENSGT00510000046467_0_Domain_1 (1184, 1391)

ETPSG---------TGS
AASGSG------------------SGQPMFQTPFTA-GLKLLTSGDPPT-------SASQ
RSSDCSMYFTGSAYSSEISQNGQQSQDV-QKKEIFPNVAEESIWRMIRQTPECILMTYQV
PKRVKE--VVLKEDLERLESMKQQQPQFSHGQQEELAKVYNWIQSQAIPQEIDVQACVTC
ESADSADD-AATSSGQAED-----SS--------------------------

--------MPGGESPDPRRLEA----D-----EEALGGE-SEMWRPRFQLQRKYVESSNS
EQQDRNRVSEELIMVVQEMKKYFPSER--HSKPSTLDALNYALRCVHSVQANSEFFQILS
Q-SGAPQADVTMYSLEELATIASEHTSKNT----------------DTFVAVFS-FLSGR
LVHISEQATVILNYKKDCLESSQFVDLLAPQDVRVFYMHTARAQLPFWNNWTQRAS-QYD
CAP-VKSFFCRIRGGEGRREQEKYYSPFRIIPYLIHVRGSAHPE----PEPCCLTLAEKI
HSGYE------APRIPVDKRIFTTTHTPGCVF

PF08447 // ENSGT00510000046467_0_Domain_0 (333, 421)

LEVDERAVPLLGYLPQDLIGTSILTYLH
PEDRSLMVAIHQK-VLKYAGHPPFEHSPIRFCTQNGDYIILDSSWSSFVNPWSRKVSFII
GRHKVQT-----------------------------------------------------
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MDPCEDRPAPGGHAL-------------------------EGPWGSWAQLQGTDGDSSHS
EQEDRKRVSEELIMVVQEMKKYLPAEK--HSKPSTLDALNYALRCVHNVQANSEFFQILS
G-NGLPQTGVTAYSPKELATIAAEHTSKNT----------------DTFVAVFS-FLSGR
LVHVSEQSTSILNCEKDFLESSHFVDLLAPQDVRVFYKHTARAQLTFWNDWTQRAS-QYE
YAP-VKSFFCRIHGGGDR-EQEKYYSPFRIIPYLVHVHSSALPE----LEPCCLALVEKI
HSGYE------APRIPVDKRIFTTTHTPECVF

PF08447 // ENSGT00510000046467_0_Domain_0 (333, 421)

LEVDERAVPLLGYLPQDLIGTSILTYLH
PEDRPLMVAIHQK-VLKHAGHPPFEHSPVRFCAQNGDFVILDSSWSSFVNPWSRKVSFVI

ENSGT00510000046467_0_Linker_0_1 (421, 1249)

GRHKVRTSPLNEDVFATRVKKINSNDKDITELQEQIHKLLLQPVHGSA--SSGYSSLGSS
GSQEQQVSAASSSESSRHCAE-----GAHKEPMTLQQVYTSVNKIKNLGQQLYIESVTKS
PV-RPMKEVRTEPSDRGEH-------------KAFSSSQLLNSKS---MYPESSEGLRKD
QHSPSYQQINCIDSVIR--YLQSCSVPALKRKCVSCTNTTSSSSEEDRQHH-GTDSAQAL
Q---------------AAAQIPAAPTPQVPAVAQSTDAKEGTT---QSLSTAALSLRSGV
SQCSCSSTLVHVPPLES------EDAT--------LACEPW-ALGA----QPAALASEEL
ACAGLTKAALSAHTQKEEQDYVDRFRERILSSPYSCYLQQDSRS--T-AEPSCVQG-DST
SKQTRSAGCKKGKHRRKKLTMPPGSSSS------DGSMCPR----TKGLLQGVQPWCPPA
APAPQASGLALSPTAVMLTSQASY--FLPTVPLS-AVTSLGAGDSAAWGAAPASLPTPPW
P-GGLHALPAVPAPYLDAFMTVLLHAPPICPPWSP----SSC--------PHSPLG----
-----------------AP-SLEPPPPVDSQGRAEDKWEARSE-EPPY-MNSRSSSPLQL
NLLQEEMPGLWASPGPARRDS-CPEAEGHRV-------------G-ESGAH---------
---------------SDLSVAPIP------------------------------------
------------------------------------------------

PF12114 // ENSGT00510000046467_0_Domain_1 (1249, 1382)

EASPSGTGAAAS
GSSGSGVHFSSSDCCSELSEDGWQSPDV-QWKEAHPNRAEDSIWRMIEQVPEQVLMTYQV
PERVKE--VVLKEDLKKLESMRQQQPQFSPGQKEELAKVHSWIQGQQVPPETRSQSCAAW
EGRGPGDEGAAESPGQHPA-----EGPPGAP---------------------

MEPRGDLETPRGEPPGPGGRGA----E-----DEALGEESGERWSPEFHLQRKLAESSHS
EQQDRNRVSEELIMIVQEMKKYFPSER--RNKPSTLDALNYALRCVHSVQANGEFFQILS
Q-NGAPQADVTMYSLEELATIASEHTSKNT----------------DTFVAVFS-FLSGR
LVHASEQAALILNRKKDVLASSHFVDLLAPQDVRVFYAHTARAQLPFWNNWTQRAAPRYE
CAP-VKPFFCRIRGGEDR-KQEKRHSPFRIIPYLIYVHRPGQPESE--SEPCCLTVVEKI
HSGYE------APRIPVNKRIFTTTHTPGCVF

PF08447 // ENSGT00510000046467_0_Domain_0 (333, 421)

LEVDERAVPLLGYLPQDLIGTSILSYLH
PEDRSLMVAIHQK-VLKYAGHPPFEHSPIRFCTQNGDYIILDSSWSSFVNPWSRKVSFII

ENSGT00510000046467_0_Linker_0_1 (421, 1180)

GRHKVRTSPLNEDVFATKIKKTNNNDKDVTELQEQIYKLLLQPVHVSV--SSGYGSLGSS
GSQEQLVSIASSSEASGHCVE-----ETKAEQMTLQQVYASVNKIKNLGQQLYIKSMTKS
SF-RPVTGTCTELNGGGESAN-----DGGEYKTFTSFHQTLKNNS---VYTEPYEDLRND
EHSPSYQQINCIDSVIR--YLKSYNIPALKRKCISCTNTTSSSSEEDKQNH-KADDVQAL
Q---------------AGLQISTIPKSEMPTNGLSIDAGGGAP---QILSTAVLSLGSGI
SQCGYSSTIVHVP-PETA-----RDAT--------LICEPW-TLNM----QPAPLTSEEF
KHVGLTAAVLSAHTQKEEQNYVDKFREKILSSPYSSYLQQESRS--K-AKYSYFQG-DYT
SKQTQLAGCRKGKHKRKKLPEPPDSSSS------NAGSGP-----HREVCQNAQPCCPST
ASSPHTLGPTF-PPAAMVPSQSPY--LVPAFPLP-AATCPGREYAAPGTVPE-GLHGPPL
S-KDLQPYPAFPSPYLDTFMTVFLPDPPVCPLLSP----SFF--------PCPFLGATAS
SAISPSMS-A------MTP-TLDPPASVTNQRREEEKWEAQSE-GHPF-ITSRSSSPLQL
NLLQEEMPRRSESPDQMRRNT-CPQAEYQCV-------------AGNSSSESSPAT----
--T------------GALSMGSPPRENPSHPTASTLSMG

PF12114 // ENSGT00510000046467_0_Domain_1 (1180, 1388)

SPPSGTPSY---------PTA
SVLSTGSPPCESLSGTGSA---------------------------------------AS
GSSNSSLYFTSSVYS-KISQNGQQSQDV-QKKETFPNVAEESIWRMIRQTPECVLMTYQV
PERVKE--VVLKEDLEKLENMRQQQPQFSHGQKEELAKVYNWIQSQTVPQEINIQACVTC
ENEDSVDG-AATSCGQALA-----EDSS------------------------

MDPGEGRLAPGARAL-------------------------EGPSGSETPLQGTDGDSGHR
-----GKLGGGLSTVLLELG-------------------------RGEGKANSEFFQILG
G-HELPLADATVYSPKELAAVAAELTCKNT----------------DTFVAVFS-FLSGR
LVHVSEQSTSILKCKKDFLESSHFVDLLAPQDVRVFYTHTARAHLPFWNNWTQRAS-QYE
SAP-VKSFFCRIQGATPRF----------GSSRLVHVHSPALSE----SEPCCLALVEKI
HSGYE------APQIPMDERIFTTTHTPGCVF

PF08447 // ENSGT00510000046467_0_Domain_0 (333, 421)

LEVDERAVPLLGYLPQDLIGTSVLTYLH
PEDRPVMVAIHQK-VLKYAGHPPFEHSPVRFRAQDGDFIILDSSWSSFVNPWSWKVSFII

ENSGT00510000046467_0_Linker_0_1 (421, 1135)

GRHKVRTRPLNEDVFATRISKMNNNDRDITELQEQIHKLLLQPVHGRS--SSSYGSLGSS
RSQEQLLSTASSSKSSGHHAEK----GTRRGPTTLQQVYARVSKMKNLGQQLCTEPTTRS
PA-EPTKGTLTELAGG-------------DAREALSSSQRLSHGV---TYTESCAGLRKG
QRSPSYQQINCIHSVIR--YLESCSAPDLKRKYVSRRNTASSSSEEDRPLH-SAHSAQAL
QGAGTG-------------------------------APASGAARTLTLSTAALSV----
GPCSCCSTLVHSPRVESE------DAS--------LACGPGGALGT----QPAALASEGL
RCTGLSQAALLAHTQKEGQDYVARFRERLLSSPCSCCLQQESGST---AESCRVQG-S--
-----------GRHKRKKLPAPPGCCSS------GSSVCPH----HKGLLYRAQPWGPAA
APAPQAPGLALPTTTVLLPGQDTR--LLPPLPVP-AMTSLGTEDAAAWGAAPAGLPTAPW
PSSGLHAPPAFPAPYSDTSMAILLHAPPICLPWSL----PFS--------PHPRSGAAGA
SEMPPAA-PA------VAP-NLEPPPSIDSQGREDDKWETHSE-EPPC-LNSRSSSPLQL
NLLQEEVPGLWLSPAPARRDL-HPKAEGISD---------------------AC

PF12114 // ENSGT00510000046467_0_Domain_1 (1135, 1367)

CQ----
--H---------------------------------------------------------
------------TSG---------------------------------KASSTSRSCGLA
GSSGSSVPLTRSDCSSELSEDKRQSPEG-QQEEARGCVPDDSIWRVIEWMPEHVLMTYQV
PVKE----VVLREDLERLESMRAQQPQFSPGQKEELAKVRPWIQGQSVLQE---------
----------------------------------------------------

MDPCGDPAVPGGDCPQTRGPGL------------------QGASGQEGPLQGTCVDSSHS
EHEDRNRMSEELIMVVQEMKKYFPAER--HTKPSTLDALNYALRCVHSVQANSDFFQSLG
P-RGAHQADVTVYSLEDLTALASEHTSKNT----------------DTFAAVFS-FLSGR
LVHISEQAALILNSKRGFLKSVHFVDLLAPQDVRAFYAHTAPTQLPFWNNWTQRAS-QYE
CAP-AKPFFCRICGGGDR--EKRHYSPFRILPYLVHVHSSAQPE----PEPCCLTLVEKI
HSGYE------APRIPVDKRIFTTTHTPGCVF

PF08447 // ENSGT00510000046467_0_Domain_0 (333, 421)

LEVDERAVPLLGYLPQDLIGTSILTYLH
PEDRPLMVAIHQK-VLKYAGHPPFEHSPVRFCTQNGEYVILDSSWSSFVNPWSRKVSFII

ENSGT00510000046467_0_Linker_0_1 (421, 1107)

GRHKVRTSPLNEDVFATRIKKAASNDKDIAELQEQIHKLLLQPVHASA--SSGYGSLGSS
GSQEQHVSITSSSESSGHCPE-----EGQHEQMTLQQVYASVNKIKNVGQQLYIESMARS
SV-KPVAETCVEPQGG-------------DEQKDFSSSQTLKNKS--TTDTGSGGNLQQE
QPSSSYQQMNCIDSVIR--YLTSYSLPALKRKCISCTNTSSS-SEEAKPIP-EVDS--SQ
R---------------DTEQLLDIRKQE--TTGPSTDIEGGAA---RTLSTAALSVASGI
SQCSCSSTSGHAPPLQSE------SVA--------VACKPW-ALRT----KASHLAAGGF
KHVGLTAAVLSAHTQKEEQNYVDRFREKILTSPYGCYLQQESRNR---AQYSCVQ-AGST
AKHSRCAGSERQKHKRKKLPAPVDTSSP------GAHLCPH----VTGLLPDEQHWGPSA
SPSPLGAGLAF-PSALVVPSQTPY--LLPSFPLQ-DMASQGVGVSAAWGAAAG---CPPL
S-AGPQAVAAFPSAYVDTLMTIFLHNAPLFPLWPP----SFS--------PYPSLGAAGS
SELAPLV-PA------MAP-NPEPTTSGHSQRRVEENWEAHSE-ELPF-ISSRSSSPLQL
NLLQEEMPAPSESADAVRRGA-GPDA

PF12114 // ENSGT00510000046467_0_Domain_1 (1107, 1387)

KHHCV-------------TGPSGSRSRHCT----
--S------------GELATATAQQES---------------------------------
--------------------------------------------------------AAAS
GSSASSIYFSSTDYASEVSENRQRPQDR-QRDEALPGAAEESIWRMIERTPECVLMTYQV
PERGRE--EVLKQDLEKLQSMEQQQPLFSPAQREELAKVRSWIHSHTAPQEGHLQSCVAC
EDRGSVGDT-AEVLEQHPAED--TS---------------------------

MEACEDLEMSRSKSQNPRGNQRPELEGPQASGPEALGKDSAEMWHQKHQLQGKYTETSHS
EQQDRDRVFEELITVVQEMKTHFPSAR--HSKPSTLDALNYALRCVHSVQANSEFFQSLR
QNNGAPQADVTVYRPEELATIASEHASKNT----------------DTFVAVFS-FLSGR
LVHISEQAPSVLNCRKELLESSPFAELLAPQDVGVFYSHTAHAQLPFWNNWTQRAS-PHD
LAP-VKSFFCRIRGGDAG-KPERLYGPFRIVPYLIHLHSPARPE----PEPCCLLLVEKV
RSGYT------APRIPENKRVFTTTHTPGCVF

PF08447 // ENSGT00510000046467_0_Domain_0 (333, 421)

LEIDERAVPLLGYLPQDLIGTSILTHLH
PEDAALMLAVHQK-VLKLAGQPPFDHSPIRFCSQNGDYIILDSSWSSFVNPWSRKISLII

ENSGT00510000046467_0_Linker_0_1 (421, 1132)

GQHQVRTSPLNEDVFATRIKKMNSNDKDITELQEQIHKLLLQPVRGGSPADGGCGSLGSS
GSPEHPVSLASSSGSSGRCEE-----EPRA-ASTLQQVHASVDKVKTPGQQLYSESMTKS
PK-KQVTGTRTAGPG--------------GEQEAFSSFQTLKNDR---MCTESCEDLETD
QHSPSYQQINCIDSVIR--FLKSHDMPALKRKCRSYTNTASSSSGEDGPNP-GAGEAPAQ
P---------------AASRIPATPASGVPATGWPIDAVGGAP---GPVDTTALDL--DV
SQSSDCSTIVHILPPES-ELTAAVDGT--------PACEPW-TLNR----HPAPLLPEDF
KHRGLTEAVPSAHMQKEEQSYVDKFREKVPSSPYSLCLQQENGG--K-TKYAHGQG-DPA
PPPTRSAGCKKGKPRRKKLLLLSDSKGA------EDSICPP----LRPEVQAGQPWCPAS
ASSPQASGLSL-AAAVMVPSPAPY--MFPALSLP-AVTSVGGEGAASGPAPP-GPPEPPV
P-RGSWSLPALPSACLDPFMNLFLHDPPVCALLSP----SFA--------SDPFLGAPGT
SELPPSV-SA------LAA-DLDAASSFISERPGEEKWGAQSE-AHPL-GLSGASSPLQL
SLLRGDRPRSGEASGPVRSDV-CLEAE-RCV-------------GGPSGNK

PF12114 // ENSGT00510000046467_0_Domain_1 (1132, 1374)

NSYFT----
--A------------SDLPTVSLHKTSPP-------------------------------
-----------------------------------------------------ETG----
----------------SAATGGQQSQDE-QRKETFPGLADDSIWRMIEQTPECVLMTYQV
PKRVKE--IVLREDLEKLESMRRRQPHFSHGQRKELAAVYAWIQSQTVPQERDTQI----
----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------APRIPMDKRIFTTTHTPGCVF

PF08447 // ENSGT00510000046467_0_Domain_0 (333, 421)

LDIDDRAVPLLGYLPQDLIGTSILMYLH
PEDRPLMITIHRK-ILKFAGQPPFEHLPIRFCTQNGDYVILDTSWSSFVNPWSRKVVFII
GRHKVRTSPLNEDVFAPRSKETSSVEKEIRELQGQIYKLLLQPVHSNV--SSGYGSLGSS
GSYEHYISIASSSDSNGNCAE------ETQEPMTLQQVCADVNRIKNLGQQLYIASRSKP
QNAS-EQAVSSEVLG-------------GKRHPASCFLQTLRGDST-EPGNTFYDDPKKT
PHIPSYQQINCVDSIIRLSYLISCIVTDLMNWELGTE---------FHVETLSFADTAML
SA--------------VESHTPISAGLEETLKDQTTAGMVGAPLADLTLSNKAPSVISVT
SQCSYSSTIVHVPHPESEVTTMEDAA------VGSEQVEPP-PVNA----PSLTVLPEDL
KPVGLTKETLSAHTQKEEQNYVDKFRQRVLLSPFRTYLQQGSGSN---NRHSCAQG-DSP
SKQMSPASYKKGKHGKFKRQKPQRQCLDSHSSSKNRN--SL---PCEKRRNQKQLFSPSE
VSYLRSSSLNVHPPVG-FP---AYSNPVSTFPT-----SSGGEQLALRSLQPQSMSSSQL
C-CGTQSYPVFYPPSIGTFMAVFFQGFPMYAQMPQHV---FLPSPPCVYPPSSYPCTTLP
PAPPPCAPSP------VAPPSVDQPFPASPHSSLEDQQEGQCDQALLL-SSSRSSSPLQL
NLLQEELPKPMELSISADVK----------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------

MDPCGDLGVPRGDGPQGLR-------------------------GASVQLQGTYADSSHS
-EPDRNRVCEELIMVVQEMKKYFPAER--HNKPSTLDALNYALGCVHSVQANSEFFQILS
P-NGAPQATVTAYSLEELASVASEHTSKNT----------------DTFVAVFS-FLSGR
LVHISEQATLILNCKKDFLKSSHFVDLLAPQDVRVFYLHTARTQLPFWNNWTQRAS-QYD
CAP-VKSFFCRIRGGGDK-EQKKYYSPFRILPYLIHVHSSGQPE----SEPCCLTLVEKI
HSGYE------APRIPVDKRIFTTTHTPGCVF

PF08447 // ENSGT00510000046467_0_Domain_0 (333, 421)

LEVDERAVPLLGYLPQDLIGTSILSYLH
PEDRPLMVAIHQK-VLKYAGHPPFEHSPVRFCTQNGDYIILDSSWSSFVNPWSRKVSFII
GRHKVRTSPLNEDVFAARVKKMNNNDKDITELQEQIHKLLLQPVHASA--SSGYGS---S
GSQEHHVSIASSSESSGHGVE-----EAQKEPMTLQQVYASVSEIKNLGQQLYIESMTRL
PV-KPVVVTHMELQGAGESAN-----TKPCTHTSAFYISSFAHKA---AMIL--------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------

------------------------------------------------------------
--------SEELLMVVQEMKKYFPSGR--HSKPSTVDALNYALCCIHSVQANSEFFQTLS
Q-RGAPCAAATAYGLEELATAALGYASKNP----------------ETFVAVFS-FLSGR
LVHISEQATSVP----NFLESSHFVELLAPQDVRVFCAHTGPAQLPAWNPKSQAAS-QYE
FAP-VKSFFCRIRGGQDT-EQEKHYCPFWIIRSVMHVHRSPQPE----SEPCCLPLVGRI
HSGYE------APRIPVDKRIFTTTHTPGCV

PF08447 // ENSGT00510000046467_0_Domain_0 (332, 429)

FLETDERAGPLLGYLRQDLMGTSVLAFLH
PEDRSLMLAVHQK-VSKYAGHPPFEHSSIRFCTQNGDDVILDSSWSSFVSP-SWKVSFIM
GGHKLRRSPLNEDVFATRKRKANSNDKDITELQEQIHRLLLQPVPASA--ASGYGSWAAS
RRPTSS----SSSVRKNVCKKKIPPSEVLFPAWTLQQVYASVNKIKNPGQQLYIESVAKS
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------

-------------------------------------EESGKRWSPEFHLQRKLADSSHS
EQQDRNRVSEELIMVVQEMKKYFPSER--RNKPSTLDALKYALRCVHSVQANSEFFQILS
Q-NGAPQADVSMYSLEELAAIASEHTSKNT----------------DTFVAVFS-FLSGR
LVHISEQAALILNRKKDVLASSHFVDLLAPQDVRVFYAHTARAQLPFWNNWTQRAAARYE
CAP-VKPFFCRIRGGEDR-KQEKCHSPFRIIPYLIHVHHPAQPESE--SEPCCLTVVEKI
HSGYE------APRIPVNKRIFTTTHTPGCVF

PF08447 // ENSGT00510000046467_0_Domain_0 (333, 421)

LEVDEKAVPLLGYLPQDLIGTSILSYLH
PEDRSLMVAIHQK-VLKYAGHPPFEHSPIRFCTQNGDYIILDSSWSSFVNPWSRKVSFII

ENSGT00510000046467_0_Linker_0_1 (421, 1242)

GRHKLVCLL--------------------------------LPIHVTA--SCGMERD---
-------------------------------------------------QPVYVLNYMLG
TF-N-----------CTSLYS-----VSGECKTFTSFHQTLKNNS---VYTEPCEDWRND
EHSPSYQQINCIDSVIR--YLKSYSIPALKRKCISCTNTTSSSSEEDKQNH-KADDVQAL
Q---------------AGLQIPAIPKSEMPTNGRSIDTGGGAP---QILSTAMLSLGSGI
SQCGYSSTIVHVPPPETA-----RDAT--------LFCEPW-TLNM----QPAPLTSEEF
KHVGLTAAVLSAHTQKEEQNYVDKFREKILSSPYSSYLQQESRS--K-AKYSYFQG-DST
SKQTRSAGCRKGKHKRKKLPEPPDSSSS------NTGSGP-----RRGAHQNAQPCCPSA
ASSPHTSSPTF-PPAAMVPSQAPC--LVPAFPLP-AATSPGREYAAPGTAPE-GLHGPPL
S-EGLQPYPAFPFPYLDTFMTVFLPDPPVCPLLSP----SFF--------PCPFLGATAS
SAISPSMSSA------MSP-TLDPPASVTSQRREEEKWEAQSE-GPPF-ITSRSSSPLQL
NLLQEEMPRPSESPDQMRRNT-CPQAEY-CV-------------TGNNGSESSPAT----
--T------------GALSTGSPPRENPSHPTASALSTGSPPMENPSH---------PTA
STLSMGLPPSGT----------------------------V

PF12114 // ENSGT00510000046467_0_Domain_1 (1242, 1388)

LSTGSPPSESPSRTGSAAS
GSSDSSIYLTSSVYSSKISQNGQQSQDV-QKKETFPNVAEEPIWRMIRQIPERILMTYQV
PERVKE--VVLKEDLEKLESMRQQQPQFSHGQKEELAKVYNWIQSQTVTQEIDIQACVTC
ENEDSADG-AATSCGQVLV-----EDSS------------------------

MDPCEDRPAPGGHAL-------------------------EGRWGSCARLQGTHGDGSRS
EQEDRKRVSEELRMVVQEMKKYLPAER--HSKPSTLDVLTYALRCVRNVQANSEFFQILS
G-NGLPQTDVTVYSPKELAAVAAEHTSKNT----------------DTFVAVFS-FLSGK
LVHISEQSASILNCEKDFLESRRFVDLLAPQDVRVFCTHTARAQLPFWNNWTQRAS-QYE
YAP-VKSFFCRIHRGGDR-EQEKSYSPFRLLPYLVHVHSSALPG----LEPCCLALLEKM
RSGYE------APRIPANKRIFTTTHTPGCVF

PF08447 // ENSGT00510000046467_0_Domain_0 (333, 421)

LEVDERAVPLLGYLPQDLIGTSILTYVH
PEDRPLMVAIHQK-VLKYAGHPPFEHSPIRFCAQNGDFVILDSSWSSYVNPWSRKVSFII

ENSGT00510000046467_0_Linker_0_1 (421, 1260)

GRHKVRTSPLNEDVFAARIKKMNNNEKDITELQEQIHKLLLQPVHGSG-YGSGYGSLGSS
GSQEQQVSVTSSSECSGHCVE-----GTRKEPMTLQQVYASVNKIKNLGQQLYIESRTRS
PA-R------TEPSG------------GGESHKAFSSFQMLNNKN---LTTESCEDLRKD
QHSPSYQQINCIDSVIR--YLKSCSVPALKRKCVSCTNTASSSSEEDRQLI-PESCFY--
--------------------ITVLWLVGFNFERPVHGCRGGAA---LS--LPPAALSSGV
SWCSCSSTLVHVPRLDS------EFAA--------LPCEP------------GALSTAES
RGPGLTTAALSAHTQREEQDYVDRFLERLLSRPYGRCLQRESRS--EKAECSCARA-AST
SKQSRPAGCRKEKHKRQKLPTPLGGSSS------DSSMSPR----SRGLLPGTQPCCPPA
GPAARPSGLALPCTTVMLPSPAPH--LL---ALP-AVTSLGAQSTEAWGPAPVSLPTPPW
P-SGLHTLPAPPAPSLDTFMTILLHAPPICPPWSP----SFS--------PHPTWGASGA
SEMPPAA-SQ------VAA-NLETPCSVESHRREEDKWEACSE-EPPS-VNSRSSSPLQL
NLLQEEMPEPGASRDSMRRDI-CPEAEGVT------------------------------
------------------------------------------------------------
-----------------------------------------------------------

PF12114 // ENSGT00510000046467_0_Domain_1 (1260, 1376)

A
GSSGSGAHLTSSDRSSERSEKAWQSPGA-QQEGAQPPLAEDSIWRMIEQMPERVLMTYQV
PARVKE--VVLKEDLAKLESMRRQQPQFSPRQKEELAKMHLWIQGQSIPQEAHVRVSVGT
AVFIGAALGGLS----------------------------------------

------------------------------------------------------------
------------MMMIQEMKRCLPEEKRSSNKPSTISALNYALQCVQQVQANNDFFQAFN
D-RRAFQADVVTYSIEELVAVASEHTPKNT----------------DTFVAVFS-LLSGR
IVHISEQAASILNCKKKVLDSSRFVELLVPQDVSVFYTHTDQSHLPLWNMESQT-ASPYE
YAQ-VKSFFCRIRGGKDQ-EQEARCYPFRITPYLVHVCTSVRVD----AESCCLALAEKI
HSGYE------APRIPMDKRIFTTTHTPGCVF

PF00989 // ENSGT00510000046467_0_Domain_0 (333, 420)

LDIDDRAVPLLGYLPQDLIGTSILMYLH
PEDRPLMITIHRK-ILKFAGQPPFEHLPIRFCTQNGDYVILDTSWSSFVNPWSRKIVFI

ENSGT00510000046467_0_Linker_0_1 (420, 1194)

I
GRHKVRTSPLNEDVFAPRSKEMSSVEKEIRELQGQIYKLLLQPVHSNV--SSGYGSLGSS
GSYEHYISIASSSDSNGNCAE------ETQEPMTLQQVCADVNRIKNLGQQMYIASRSK-
-NAN-EQAVSSDILG-------------GKRHTASCFLQTLRGDSTDDPGNTFYDGPKKT
PHVPSYQQINCVDSIIR--YLESCSIPALKRKCKSSANTSSSSSEDDKQVQQSQQQVRAL
EA--------------VESHTPISAGLEETLKDQTTAGMVGAPLADLTLSNKAPSVISVT
SQCSYSSTIVHVPHPESEVTTMEDAA------VGSEQIELP-PVNA----QSLAVLPEDL
KPVGLTKETLSAHTQKEEQNYVDKFRQRVLLSPFRTYLQQGSRSN---NRHSCGQG-DSP
AKQMSPASCKKGKHGKFKRQKPQRQCSDSHSSSKNRN--SL---PCEKKTNQKQLFSPSE
VSYLSSSSLNVHPPVG-FP---AYSNPVSTFPA-----SSGGEQLALRSLQPQSMSSSQL
Y-CGTQSYPVFYPPNIGTFMAVFFQGFPMYAQMPQHV---FLPSPQCVYPPSSYPCTTLP
PAPPPCAPSP------AAPHSVDQPFPASPHSSVEDQQEGQCDQALLL-SSSRSSSPLQL
NLLQEELPKPMELSVSADVKP-QAEDK--CD-----------------------------
--------------------------------------------NDPEDNGNN

PF12114 // ENSGT00510000046467_0_Domain_1 (1194, 1387)

AA-----
LEFPDRSLYEDSQLGSGSAASGSGSALSGSLSS----------------SFNETSGHGTA
S------------------KEE-KNQEA-EEKGTAYKSKHESACVMMDYTPERVLMNYQM
PNRVKE--EVLKQDLEKLAVMQKQQPWFTDGQKKELAEVHSWIRTQTVPLQISTQGCVTC
DSREASCEAA-------VADD--SMENKGEPPPVLPR---------------

------------------------------------------------------------
---------------------------------------------------NSEFFQILG
G-HELPLADATVYSPKELAAVAAELTCKNT----------------VRTTSLAVSALVTF
PKAFSVPPLKKQKCKKSLVDKLHIVLLE----IIVQVTKAGAGDLAQWHKH-MPSS-QYE
SAP-VKSFFCRIQGATPRF----------GSSRLVHVHSPALSE----SEPCCLALVEKI
HSGYE------G-------KIFTTTHTPGCVF

PF08447 // ENSGT00510000046467_0_Domain_0 (333, 421)

LEVDERAVPLLGYLPQDLIGTSVLTYLH
PEDRPVMVAIHQK-VLKYAGHPPFEHSPVRFRAQNGDFIILDSSWSSFVNPWSRKVSFII

ENSGT00510000046467_0_Linker_0_1 (421, 1135)

GRHKVRTRPLNEDVFATRISKMNNNDRDITELQEQIHKLLLQPVHGRS--SSSYGSLGSS
RSQEQLLSTASSSKSSGHHAEK----GTRRGLTTLQQVYARVSKMKNLGQQLCTEPTTRS
PA-EPTKGTLTELAGG-------------DAREALSSSERLSHGV---TYTESCAGLRKG
QRSPSYQQINCIHSVIR--YLESCSAPDLKRKYVSCRNTASSSSEEDRPLH-SADSAQAL
QGDGTG-------------------------------APASGAARTLTLSTAALSV----
GPCSCCSTLVHSPP---E------DAS--------LACGPGGALGT----QPAALASEGL
RCTGLSQAALLAHTQKEEQDYVARFPERLLSSPCSCCLQQESRSR---AESCRVQG-AAA
SRHSRPAGCRKGRHKRKKLPAPPGRCSS------GSSVCPH----HKGLLYRAQPWGPAX
XXAPQAPGLALPSTTVLLPSQDTR--LLPPLPVP-AMTSLGTEDAAAWGAAPAGLPTAPW
PSSGLHAPPAFPAPYSDTSMAILLHAPPICLPWSL----PFS--------PHPRSGAAGA
SEMPPAA-PA------VAP-NLEPPPSIDSQGREDDKWETHSE-EPPC-LNSRSSSPLQL
NLLQEEVPGLWLSPAPARRDL-HPKAEGISD---------------------AC

PF12114 // ENSGT00510000046467_0_Domain_1 (1135, 1367)

CQ----
--H---------------------------------------------------------
------------TSG---------------------------------KASSTSRSCGLA
GSSGSSVPLTRSDCSSEPSEDERQSPEG-QQEEARGCVPDDSIWRVIERMPEHVLMTYQV
PARGRGVHFFSLEDLERLESMRAQQPQFSPGQKEELAEVRPWIQGQSVLQE---------
----------------------------------------------------

MDLCGDLETPSRKSPESGATEPRDIPG-----PRARGEEPGTKWSQKHLLAAEFGAGNNS
EQQDRNRVSEELMMVVKEMKKYFPSER--HSKPSTLDALTYALRCVNSVQANSEFFPILG
Q-NGTPQTDVTTYSLEELATIASEHTSKNT----------------DTFVAVFS-FLSGR
LVHISEQATSILNCERDFLESSHFVELLAPQDVRVFYAHTAHAQLPAWNSWTRKAASQYD
YAP-VKSFFCRIRGGAVR--EQRYYCPFRIIPYLIHVHRPVQPE----AEPCCLTLVEKI
HSGYE------APRIPVDKRIFTTTHTTGCIF

PF08447 // ENSGT00510000046467_0_Domain_0 (333, 421)

LEVDERAVPLLGYLPQDLVGTSLLMYLH
PEDRSLMVAIHQK-VFQYAGQPPFEHSPIRFCTQNGDYIILDSSWSSFVNPWSRKVSFII
GRHKVRMSPLNEDVFATRVKKMNSKDKDIAELQEQIHKLLLQPVHISA--SSGYGSLGSS
GSQEHHISVASSSESSGHCVE-----EPQKEPMTLQQVYANVNKIKNLGQQLYIDSLTKS
PN-KQVMGTSTGLHS-------------GDQQKAFSSFQTLKHNS---MYTESCEDLRKD
QHNPSYQQINCIDSIIR--YLKSYNIPALKRKCISCTNTTSSSSEDDRQNH-KADIK-AL
P---------------AVSQTPVMAASEVKTPGPSTDTEEGVP---RTLSTRALSWVSGV
SQCSYSSTMVHAPPPESGTM----------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------

MDPCGDPAKPGGDCPHSRGQGL------------------QGAAGQEGPLLGTSVDSSHS
EHEDRNRMSEELLKVVQEMKKSFPAER--HTKPSTLDALNYALRCVLSVQANSGFFPSLG
P-HGAPQTDVTAYSPEELASITSELASKNTFQYLLPQVVTAGFVEQDTFVAVFS-FLSGR
LVHISEQAALILNSKKDTLESSHFVDLLAPQDVSVFYTHTAPTQLPFWNNWTQRAS-QCE
YAP-VKSFFCRICGG-GDRAQKKLCSPFRILPYLVHVQNSAQPE----PEPCCLALAEKI
HSGYE------APRIPVDKRIFTTTHTPGCVF

PF08447 // ENSGT00510000046467_0_Domain_0 (333, 421)

LEVDDRAVPLLGYLPQDLIGTSILTYLH
PEDRPLMFAIHQK-VLKYVGHPPFEHLPIRFCTQNGDYIILDSSWSSFVNPWSRKVSFII
GRHKVRTSPLNEDVFATRIKKATNNDKDITELQEQIHRLLLQPVHARA--SSGYGSLGSS
GSQEQHISIASSSESSGHCVE-----EAQKEQVTLQQVYASVNKIKNVGQQLYIESMSR-
SV-KPVMDTRMELQGG-------------DEQKDFSPSQTL---KNKYMCTGSCDDLRRE
QHSSSYQQMNCIDSVIR--YLRSYSLPALKRKCISYTNTSSS-SEEAKQNH-EADCSTAL
Q---------------DTEQILDIHKSETPATGPSTDADGGAA---WTLSTAALSMGSGI
SQCNCSSTAVHAPPLHSE------GAV--------LVCKPW-SPRT----QPSPLTAEEF
RHVGLTAAVLSAHTQKEEQNYVDRFRERILTSPYSCYLQQESRNN---AKCSSV--QGSP
PKQSRCAGKERRKHKRKRLPVPLGTSSS------SANFCSH----IRGLLPDVQPWSPSI
VCSPHAESLAF-PAALVAPSQAPY--VLSSFPFP-DVASLGVGDSAGWGAAVE---CPPL
S-TGPQSVPAFPSAYLDTFTTIFLHNSPIFPLWSA----SFP--------SYPFLGATAS
SGMTPLV-PA------MAP-HLEPTSSDHSQRRVGESWETHGE-EHPF-ISSRSSSPLQL
NLLQEEMPAPSESPDPVRKGI-GPESECVSV-------------ST--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------

------------------------------------------------------------
-------------MVVQEMKKYFPAER--RSKPSTLDALNYALRCVRSVQANSEFFQIHN
L-NGAPEREVTVYSLKELATVASELTSKNT----------------DTFVAVFS-FLSGR
LVHISEQAALILNCKKDFLKSCHFVDLLAPQDVRVFYTHTARAQLPFWSSWSQRAS-QYE
CAP-VKPFFCRIRGGGGR-EHEKHYSPFRIIPYLVHVHSSTQPE----SEPCCLTLVEKI
HSGYE------APRIPVDKRIFTTTHTPGCVF

PF08447 // ENSGT00510000046467_0_Domain_0 (333, 421)

LEIDERAVPLLGYLPQDLTGTSVLACLH
PEDRPLMVTMHQK-VLKYAGHPPFEHSPIRFCTQNGDYIILDSSWSSFVNPWSRKVSFII

ENSGT00510000046467_0_Linker_0_1 (421, 1104)

GRHKVRTSPLNEDVFATRIKKTNSNEKDITELQEQIHRLLLQPVHVST--SSGYGSLGSS
GSQELQVSVDSSSESSGHCLE-----EVQKEPMTLKQVYSSVNKIKNLGQQLYIDSMARS
SV-KPVMGTCPEPSG-------------GDEQKASSSSLTLKNKC---TCTEFCEDLRKD
QHSSSYQQMNCIDSVIR--YLKSYHIPALKRKCVSSTNTMASSSEEEKPSH-QADDTQAV
Q---------------AVAQTPAMPQPKVPTNGRPTEAEADLA---GTLSTATLSLGSGT
SQCSCSSTIVHVPPPEPA-----EDAA--------LGCEPW-TLNT----QPAPFTAEEF
KHVGLTTASLSAHTQREEQDYVDRFRKKILSSPYSCCLHRESSS--K-ARRSCVQG-DFT
SKQSRLAGCRKGKHKRTKPPVPLGSSSS------SDSFHSQ----AGGPLQDVLPWCPST
PSSACASGLGF-PAAVMVPSQSSY--LLPAFPLP-A-----------WAATPECPPKPPV
S-SGLQHLPALPSLHVDTLMTFFLHNPRICPLWSP----SFS--------PYPFLGATDS
SEILPSV-SA------VAP-NLEPPPSVNS-GRVEENWEMQKE-EHLF-ISSRSSSPLQL
DLLHEDMPASPEPPDAVRRDA-G

PF12114 // ENSGT00510000046467_0_Domain_1 (1104, 1386)

PEATDHCV-------------SGGGGSRSSS-A----
--A------------GDLSPAPPH------------------------------------
------------------------------------------------KVSPSGAGSAAS
GSSSSCIFFTSTDYSSESSENGQQSQDT-QKTSAFHSLAEDPIWKMIAQTPECVLMTYQV
PERVKE--VVLKEDLEKLESLRQQQPQFSPGQKEELAKVHPWIQSQTVPGGMHVQSCATC
EDGGSAGDT-AEAPGRIQEKT--AAEPP------------------------

------MQCSKSDGN---DSSGNEFNGPESNGTDSLDKESDEIWKQSFKQQNKTVTD-NS
EQQDRNKTSEELMMVVREMKKYLPSER--NHKPSILDALNYALRCVNSVQANNEFFQILR
P-NGAHQTDVTKYSLKELATIASEHTSKNT----------------DTFVAVFS-FLSGK
LVHVSEQAALILNRKKNSLASSPFVELLDPQDVRVFYAHTAQAHLPFWNVSTQTAS-QYE
YSQ-VKPFFCRIRGGKDR-EQETYYYPFRITPYLINVYNSTDTE----SEPCCLALVEKI
HSGYE------APRIPVNKRIFTTTHTPGCMF

PF00989 // ENSGT00510000046467_0_Domain_0 (333, 420)

LEVDERAVPLLGYLPQDLIGTSILMYLH
PEDRPLMFAVHQK-ILKYAGQPPFEHSPIRFCTQNGDYVILDSSWSSFVNPWSRKVSFI

ENSGT00510000046467_0_Linker_0_1 (420, 1132)

I
GRHKVRTSPLNEDVFATRIKNMSSIDKDIMELQDQIYKLLLQPVHVGG--SSGYGSLGSN
GSQEHYISIASSSESSGNCVE-----EIQKEPMTLQQVCATVNRIKNLGQQLYIESRTKL
SN-QQFTISNTEQQG--------------NKKPSHPSSQELRNSS---LGTDSCDDLRKD
QHVPSYQQINCVDSIIR--YLESYNIPALKRKCISCTNTTSSSSE-EDHISQRPAGAQAL
E---------------SIPQIPVLATPARAD------------NEELALSPKAMSVLSAT
SQCSYRSTLVHVPHPESEV-TAGDDVI-----AGNEQAEAR-SLSL----QTFPVAPEEF
KQVGLTKAVLSAHTQKEEKNYVDRFREKILSSPYCSYLQPDGKSK---MKYATIQG-DAP
SKQATSAGCKKGKHKRQKLPISSCSSDS------RENFPSL----LGKPPPGRPPWLPSD
LTPPHPCGLLH-PPLAGVPMQAPS--PVTGFPALPSMSSLRTQYTASAPELG-PQPGLHP
S-YRMQPLPAFPSPYVGAFMTIILHNPPPYPQTCQ----PFS-------PPCPFSCVPGS
SEIPPPPPPPSSPALPVED-LPEPPSPTSSQRSAEEEWALQSEQEHPLFSHSRSSSPLQL
NLLQEEMPGAPEP-LQYTGSEADPGAQHQSK-------------AG-DNKK

PF12114 // ENSGT00510000046467_0_Domain_1 (1132, 1386)

SHNSV----
--A------------KELFTLLLQKDSP--------------------------------
-------------AGAGSVASGSGSVKSNSS------------GSDANGSFSHGTSGCGT
GSSDSSKYFASSDYSSETSQNRQKSE----EKETPHKSGRDAIWGMIKQTPECVLMTYQV
PERVKE--DVLKEDLEKLESMRQHQPHFTDGQKEELAEVHPWIQSQMVPREIDTHGCVTC
DNKHSLGVGPLP-YEKSLEEDIWVTDQ--EDLPAQP-------FQDRK-L--

--------MPRGEAPGPGRRGA----K-----DEALGEESGERWSPEFHLQRKLADSSHS
EQQDRNRVSEELIMVVQEMKKYFPSER--RNKPSTLDALNYALRCVHSVQANSEFFQILS
Q-NGAPQADVSMYSLEELATIASEHTSKNT----------------DTFVAVFS-FLSGR
LVHISEQAALILNRKKDVLASSHFVDLLAPQDMRVFYAHTARAQLPFWNNWTQRAAARYE
CAP-VKPFFCRIRGGEDR-KQEKCHSPFRIIPYLIHVHHPAQPELE--SEPCCLTVVEKI
HSGYE------APRIPVNKRIFTTTHTPGCVF

PF08447 // ENSGT00510000046467_0_Domain_0 (333, 421)

LEVDEKAVPLLGYLPQDLIGTSILSYLH
PEDRSLMVAIHQK-VLKYAGHPPFEHSPIRFCTQNGDYIILDSSWSSFVNPWSRKISFII

ENSGT00510000046467_0_Linker_0_1 (421, 1243)

GRHKVRTSPLNEDVFATKIKKMNDNDKDITELQEQIYKLLLQPVHVSV--SSGYGSLGSS
GSQEQLVSIASSSEASGHRVE-----ETKAEQMTLQQVYASVNKIKNLGQQLYIESMTKS
SF-KPVTGTRTEPNGGGESAN-----GGGECKTFTSFHQTLKNNS---VYTEPCEDLRND
EHSPSYQQINCIDSVIR--YLKSYNIPALKRKCISCTNTTSSSSEEDKQNH-KADDVQAL
Q---------------AGLQIPAIPKSEMPTNGRSIDTGGGAP---QILSTAMLSLGSGI
SQCGYSSTIVHVPPPETA-----RDAT--------LFCEPW-TLNM----QPAPLTSEEF
KHVGLTAAVLSAHTQKEEQNYVDKFREKILSSPYSSYLQQESRS--K-AKYSYFQG-DST
SKQTRSAGCRKGKHKRKKLPEPPDSSSS------NTGSGP-----RRGAHQNAQPCCPSA
ASSPHTSSPTF-PPAAMVPSQAPY--LVPAFPLP-AATSPGREYAAPGTAPE-GLHGLPL
S-EGLQPYPAFPFPYLDTFMTVFLPDPPVCPLLSP----SFL--------PCPFLGATAS
SAISPSMSSA------MSP-TLDPPPSVTSQRREEEKWEAQSE-GHPF-ITSRSSSPLQL
NLLQEEMPRPSESPDQMRRNT-CPQTEYQCV-------------TGNNGSESSPAT----
--T------------GALSTGSPPRENPSHPTASALSTGSPPMKNPSH---------PTA
SALSTGSPPMKNPSHPTASTLSMGLP--PSRTPSHPTATV-L

PF12114 // ENSGT00510000046467_0_Domain_1 (1243, 1388)

STGSPPSESPSRTGSAAS
GSSDSSIYLTSSVYSSKISQNGQQSQDV-QKKETFPNVAEEPIWRMIRQTPERILMTYQV
PERVKE--VVLKEDLEKLESMRQQQPQFSHGQKEELAKVYNWIQSQTVTQEIDIQACVTC
ENEDSADG-AATSCGQVLV-----EDSC------------------------

------------------------------------------------------------
-----NKVSGELITVVQEMKKYLPAER--RNKPSTLDALNYALRCVHSVQANSEFFQILS
P-YGAARADMTAYSLEELATVVSQHTFKNT----------------DSFAAVFS-FLSGR
LVHISEQAALILNCKKDFLESSHFVDLLAPQDVKVFYTHTARAQLPVWNSWTRGAS-QYE
YTP-VKPFFCRIRGGRDK-VQEKHYSPFRILPYLVHVHSSAQPE----SEPCCLTLIEKT
HSGYE------APRIPVGKRIFTTTHTPGCVF

PF08447 // ENSGT00510000046467_0_Domain_0 (333, 421)

LEVDERAVPLLGYLPQDLIGTSILTYLH
PEDRPLMFAMHQK-VLKYVGHPPFEHSPVRFRTQNGDYIILDSSWSSFVNPWSRKVSFII

ENSGT00510000046467_0_Linker_0_1 (421, 1125)

GRHKVRTSPLNEDVFATRIKQTNSSDKDITELQEQIHKLLLKPVHASA--SSGYGSLGSS
GSQEQLVSITSSSESSGHWAE-----DMPKEPMTLEQVYANVNEIKNLGQQLYIESKTKS
SSVKPGMRMRTEL--------------QGDAQKAFISSQTLENKS---MHTEPCEDLREE
QHSPSYQQINCIDSVIR--YLKSYSIPTLKRKCISCTNTTSSSSEEDRQSH-KADSGQTP
Q---------------------------------GNSTTGGGA---WTMSMAALSVGSAV
SPCRSSSIASQAPSLTSA-----EDAT--------MVCEPW-ALEA----RPVPLTAEEM
RHVGLTAAVLSAHTQKEEQNYVDSFREKILASPYSCYLQQESRS--K-AKYSYVQA--SP
SKQSRSTWSKKGQHKRQRLPVPLDASSC------GPGLCPH----AGALLPGVQPWGPPT
AASPSASGLPS-PSTLLVPSQAPY--LLPVCPLL-ALTSVGGGSLTAWAAAP----GCPL
A-SSRQAPPAPPPPHVDTRMTIVLPSPAVCSLWPP----PSS--------PYLFLGDPGS
PEVPTPI---------PAP-NLEPPTYASNQRRAEEKWETQSG-EHLL-LGSRSSSPLQL
NLLQEEMPASSESARPAGRGA-CPDIMPFFT-------------

PF12114 // ENSGT00510000046467_0_Domain_1 (1125, 1388)

GSK----SRHAL----
--A------------SES----LA------------------------------------
-------------------------------------------------ACAAARPRNAV
SSSGSSMSFISSDYSLEISRNGQQSQGV--QEKALPRPAAESIWRMIEQTPERVLMTYQM
PERVKD--AVLKEDLERLESMRRHQPHFSPGQKEELAKVHSWIQSQNIPPGSRV----AC
ANRSSAEH-SAEPVGCIQEKT--SA---------------------------

------MQSSKSDSN---DSNGNEFNEPESSGTDSLNKESHERWNKDFRRQGKDSTDNNS
EQQDRNKTSEELMMVVREMKKYFPSEK--NHKPSILDALNYALRCVHSVQANNEFFQILG
P-NGAHQTDVTKYSLEELVTIASEHTSKNT----------------DTFVAVFS-FLSGK
LVHVSEQAPLILNCKKNSLASSPFVELLAPQDVRVFCTHTAQAHLPFWNVSTQTAS-QYE
YSQ-VKPFFCRIRGGKDR-EHEALYYPFRITPYMINVHSSADTE----SEPCCLALVEKI
HSGYE------APRIPVNKRIFTTTHTPGCV

PF00989 // ENSGT00510000046467_0_Domain_0 (332, 420)

FLEVDERAVPLLGYLPQDLIGTSVLMYLH
PEDRPLMFAVHQK-ILKYAGQPPFEHSPIRFCTQNGDYVVLDSSWSSFVNPWSRKVSFI

ENSGT00510000046467_0_Linker_0_1 (420, 1134)

I
GRHKVRTSPLNEDVFATRIKKMSSIDKDIMELQDQIYKLLLQPVHIGG--SSGYGSLGSN
GSQEHYISIASSSESSGNCVE-----EMQKEPMTLQQVCATVNQIKNVGQQLYIESRTKV
SN-QQQFAGSESRGG--------------DKKSSHPSSQELRNGS---LGTDSCDDLRKD
QHIPSYQQINCVDSIIR--YLKSYNIPALKRKCISCTNTTSSSSEEDQHISQRPAGAQAL
D---------------AFPQIPVLDTPVGTED----------DRPALALSPKAMSVLSTT
SQCSYRSTLVHVPHPESEV-TAGDDAA-----VGPDQAEAR-SLSL----QACSAVPEGF
RQLGLTKAVLSAHTQKEEKNYVDRFREKILSSPYCSYLQPDGKSR---PHYPLVPG-EAA
SKQMPSASGKKGRHKRLKLPASSHNSGS------WE----------NSLPLGRPPWPPAD
VASPS----------------APS--LLAGFPVLPSVSPVGAQCPALMPGLR-PQPGPNP
S-CRVPPLLAFPSPYMGAFMTIVLHSPPACPQMCP----PFS-------SPCPFLSVPGC
AEAAPV-PPPSPPVLPQEP-PPELPSLASSQRSAKEEWALQSEQEHPLFSHSRSSSPLQL
NLLQEEMPGATEPPLPALGQEAEAGAQHR-Q-------------AG-DSERGR

PF12114 // ENSGT00510000046467_0_Domain_1 (1134, 1372)

DSA----
--T------------QGLFTLLLPKDSV--------------------------------
-------------VGAGSAALGSGSVSS-----------------EAMGSLPHDMSGCGT
GSNDSSRYFASSDYSSETSQNEQKSE----EKEAPHKSGRDAVWGMIEQTPESILMTYQV
PERVRE--DVLKEDLEKLESMRQQQPRFTDGQKEELAEVHPWIQSQGVPRETGSPVSSP-
-ESYRRGGDPLP-R--------WGEGRDGPGLPHCPP------AAGRR----

--------MPRGEAPGPGRRGA----E-----DEALGEESGERWSPEFHLQRKLADSSHS
EQQDRNRVSEELIMVVQEMKKYFPSER--RNKPSTLDALNYALRCVHSVQANSEFFQILS
Q-NGAPQADVSMYSLEELAAIASEHTSKNT----------------DTFVAVFS-FLSGR
LVHISEQAALILNRKKDVLASSHFVDLLAPQDVRVFYAHTARAQLPFWNNWTQRAAARYE
CAP-VKPFFCRIRGGEDR-KQEKCHSPFRIIPYLIHVRHPAQPESE--SEPCCLTVVEKI
HSGYE------APRIPVNKRIFTTTHTPGCVF

PF08447 // ENSGT00510000046467_0_Domain_0 (333, 421)

LEVDEKAVPLLGYLPQDLIGTSILSYLH
PEDRSLMVAIHQK-VLKYAGHPPFEHSPIRFCTQNGDYIILDSSWSSFVNPWSRKVSFII

ENSGT00510000046467_0_Linker_0_1 (421, 1241)

GRHKVRTSPLNEDVFATKIKKMNNNDKDITELQEQIYKLLLQPVHVSV--SSGYGSLGSS
GSQEQLVSIASSSEASGHCVE-----ETKAEQMTLQQVYASVNKIKNLGQQLYIESMTKS
SF-KPVTGTRTEPNGGGESAN-----GGGECKAFTSFHQTLKNNS---VYTEPCEDLRND
EHSPSYQQINCIDSVIR--YLKSYNIPALKRKCISCTNTTSSSSEEDKQNH-KADDVQAL
Q---------------AGLQIPAIPKSEVPTNGRSIDTGGGAP---QILSTAMLSLGSGI
SQCGYSSTIVHVPPPETA-----RDAT--------LFCEPW-TLNM----QPAPLTSEEF
KHVGLTAAVLSAHTQKEEQNYVDKFREKILSSPYSSYLQQESRS--K-AKYSYFQG-DST
SKQTRSAGCRKGKHKRKKLPEPPDSSSS------NTGSGP-----RRGAHQNAQPCCPSA
ASSPHTSSLTF-PPAAMVPSQAPY--LVPAFPLP-AATSPGREYAAPGTAPE-GLHGPPL
S-EGLQPYPAFPFPYLDTFMTVFLPDPPVCPLLSP----SFF--------PCPFLGATAS
SAISPSMLSA------MSP-TLDPTPSVTSQRREEEKWEAQSE-GHPF-ITSRSSSPLQL
NLLQEEMPRPSESPDQMRRNT-CPQAEY-CV-------------TGNNGSESSPAT----
--T------------GALSTGSPPRENPSHPTASALSTG---------------------
------SPPMENPSHPTASTLSMGLP--PSGTPSHPTATV

PF12114 // ENSGT00510000046467_0_Domain_1 (1241, 1388)

-LSTGSPPSKSPSRTGSAAS
GSSDSSIYLTSSVYSSKISQNGQQSQDV-QKKETFPNVAEEPIWRMIRQTPERILMTYQV
PERVKE--VVLKEDLEKLESMRQQQPQFSHGQKEELAKVYNWIQSQTVTQEIDIQACVTC
GNEDSADG-AATSCGQVLV-----EDSS------------------------

MDPCGDPAVPGGDCPHSRRQEL------------------QGASDREGPLLGTLVDSSHS
KQEDRNRMSEELLMVVQEMKRSFPAER--CTKPSTLDALNHALRCVLSVQANSGFFPSLS
P-HGAPQADVTVYSPEELASLASELASKNT----------------DTFVAAFS-FLSGR
LVHVSKQAASILDSKEDALKSSHFVDLLAPQDVSVFYAHTVRSQLPFWNNWTQRAS-QCE
CAP-VKSFFCRICGG-GDRAQKKLCSPFRILPYMVHVQSSAQPE----AEPCCLALAQKI
RSGYE------APRIPVDKRIFTTTHTPGCVF

PF08447 // ENSGT00510000046467_0_Domain_0 (333, 421)

LEVDDRAVPLLGYLPQDLIGTSILTYLH
PEDRPLMVAIHQK-VLKYVGHPPFEHSPIRFCTQNGDYVILDSSWSSFVNPWSRKVSFII
GRHKVRTSPLNEDVFATRIKKATNNDRDITELQEQIHKLLLQPVHASA--SSGYGSLGSS
GSQEQHISIASSSEGSGPCGE------ASKEQMTLQQVYASVNEIKTVGQQLYIESMAR-
SV-KPVMDTCMALQGK-------------STEWPSAAPESLFTDSSVYAC----------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------

------------------------------------------------------------
--------------------------------------------------ANSEFFQILS
Q-NGAPPTDVTMYSLEKLSTIASEHTSKNT----------------DTFMAVVS-FLSGR
LVHISEQATSILNYEKDFLESFHFVELLAPQDVRVFYAHTAHAQLPFWNNWTQRAASQYE
FAP-VKSFFCRIRGGEGG-EQEKNYRPFRVISYLIHVRSPTQPG----AEPCCLMLVEKI
HSGYE------APRIPVDKRIFTTMHTPGCV

PF08447 // ENSGT00510000046467_0_Domain_0 (332, 429)

FLEVDERAVPLLGYLPQDLIGTSILMYLH
PEDRSLMVAIHQK-VLKYAGQPPFEHLPIRFCTQNGDYIILDSSWSSFVNPWSRKVSFII
GRHKVRTSPLNEDVFATRVKKVNSNDKDITELQEQIHKLLLQPVHVGD--SSGYGSLESS
GSQEHYVSIESSSESSGHCVE-----EIQKEPMTLQQVCASVNKIKNRGQQLYIESMTKS
PNKPAADGTADGKTQL---------LECISDNKKCEVKHTSKNHS---THTASSKDLRKD
GHSPSYQQINSIDSVLR--YLKSCSFPDLKRKCVSCTNTNSSSSEDGRQ-----------
----------------ILSQIPVIAKSEMTTAGQSTDAEEGVL---QTPSAKALSLVSGM
SQCSYSSTIVHVPPPEPVPGSDMHMHEQLSGLARGRMYSGG-PGCT----EAASLTSEGF
KHVGLTKAVLSAHTQKEEQNYVDKFREKILSSPYSSYLQQESTS--K-AKCSHVQG-DST
SRQTKSARWKKGKHKRKKLPVPSDSNRC------A-DICPH----FREGVQDAQPWWPPR
DFLPHSPGLSF-PSTVVMPSQAPY--LTPPP-----------------------------
P-GSLMSVPAFPAPYLDTFMTVFLHAPPACPLLPP----SFS--------PYPLLGAAGS
PEIPPSS-SP------EAP-GLEPPSSVTNQRRVAERWETHGE-EHPF-ISSRSSSPLQL
DLLQEEMPGSSQSPDQMKRDV-CSEAEVQEV-------------CN-SGNNNNCCP----
--A------------SELSTVLLRQNSP--------------------------------
-------------SGTHSAASGNGFGTGVGVKYFSSL--------------FASSIGRLS
GSSDSSIYFASSDYSSEISQNGHITQDA-QKKETAPNSVQESIWRMIEQTPERILMTYQV
PERVKE--VVLKEDLEKLESMRQGQPQFSREQREELAKVHSWIQSQTVPQEIDMQGCVTC
----------------------------------------------------

--------VSGGKSQDSRRRQP---------KDEALGKDSAEMWSRKYQLRSKYVQTSNS
EPQDQNRVSKDLITVVQEMKKYFPSER--QSKPSTLDALNYALRCVHSVQANSEFFQILN
Q-NGAPQADVTMYSLEELAAVASEHTSKNT----------------DTFVAVFS-FLSGR
LVHVSEQAPLILHCKKEFLESSHFVELLAPQDVRVFYTHTAHAQLPFWNNWTQRAASRYE
FAP-VKSFFCRIRGGEAQ-ELRQPYCPFRIIPYLIHVHSSARPE----PEPCCLTLVEKI
HSGYE------APRIPVDKRIFTTTHTPGCV

PF08447 // ENSGT00510000046467_0_Domain_0 (332, 373)

FLEIDERAVPLLGYLPQDLIGTSILTYLH
PEDRSLMVAIHQK-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSFVPWSRKVSFII
GRHKVRTSPLNENVFATGIKKMNSNDKDITELQEQIHRLLLQPVHGSA--SSGYGSLGSS
GSQEHHLSIASSSESSEHCME-----EVQKAPLTLQQVYASVNKIKNLGQRLYIESRAKS
PK-KQVMETDPGQRGG-----------ESAEQKTFSSFQTLKNNS---MYPESCEDLRRC
QHSPSYQQINCIDSVVR--YLKSYDIPALKRKCISCTNTTSSSSEEDGQSH-RADDVQAL
Q---------------AVSQIPAVPTSEMPANGRSTDAEGGAP---QALTKEALSL--DG
RQCSCSSTVVHMPPLESA-----ELGI--------LPCEPW-TLST----HPAALASEQF
KHTGLTKAVLSAHTQKEEPSYVDQFRDRILSSPYGSYLQQESRS--K-PTYSDVQG-DSA
SKPTRSAGCRKGKHKRKKLLMWSDSKGT------KDDFCPH----LIGETQDGQPWCPSS
TSSPYASGPLL-QAAVVVPSQAPC--LVQALPLP-TMTSLGRERAASETALQ-SLPEPPF
P-NGLQSFPALPSACLGTFMNIFLHDAPICPLLLP----PFS--------PYPFLGAAGS
SEIPASV-SA------VPP-NPGPPSSAISQRSGEGKWGTQNE-GHPL-INSKSSSPLQL
DLLQENRPRSCASPEA-----------------------------------EYHFT----
--T------------SELSTVSLHEAS---------------------------------
---------------------------------------------------PPGAGSAAA
GSSGSSINFATSDYSSEIFQNGQQSQDV-QKKETFPNLAEESIWRMIEQTPECILMTYQV
PERVKE--IVLKEDLENLESMRRRQPQFSHGQREELANVRSWIQSQTIPQEIDIQGCVTC
ENGDSAGD-AAESCRPDPAES--S----------------------------

---------------------------------------------------------SYR
EQQDRNRVSEELRMVVQEMVKYLPSER--HSKRSTLDALNYALRCVHSVQANSEFFQILS
Q-NGAPQADVTGYSLEELATIASGHTSKNT----------------DTFVAVFS-FLSGR
VVHISEQAASILNCKKAFLESSHFVELLAPRDVRVFYTHTAHAQLPFWNNWTQRAA-QYD
YAP-AKSFFCRIRGGEDS-KQEKRYSPFQILPYLIHVHSPAQLE----SEPCCLMLVEKV
HSGYE------APRIPVDKRIFTTTHSPGCVF

PF00989 // ENSGT00510000046467_0_Domain_0 (333, 420)

LEIDERAVPLLGYLPQDLIGTSVLTYLH
PEDRSLMVAIHQK-VLKYAGHPPFEHSPIRFCTQNGDYIILDSSWSSFVNPWSRKVSFI

ENSGT00510000046467_0_Linker_0_1 (420, 1106)

I
GRHKVRTSPLNEDVFATRIKKMNSNDKDITELQEQIHKLLLQPVHVSA--SSGYESLGSS
GSQEYHLSAASSSESSGHCAE-----EAQKEPLTLQQVYASVNKIKNLGQQLYIESMTRS
PD-KQVMGTRVGQLG--------------DEQKAFSSFRTLKNNS---VYTESCEDLRKD
QHSPSYQQISCIDSVIR--YLKSYNIPALKRKCISCANTTSSSSEEDRENH-QADDVQAS
Q---------------------AIPKSEMPTSGRCTDTEAGAP---QTLSAAALGLGSGI
SQCSYSSAIIHVPPLES------EDAP--------QALEPW-TLST----HPAPLTSEER
RHGGLTQAVLSAHTQKEEQNYVDKFREKMLSSPYSSYLQQESGS--K-AQYSHVQG-NST
SRQTRSAGCRKGKHKWKKLPVPSDGRSS------KDTFCPH----CRGEVQNVQPHCPAP
ALPPPATGLSF-PAAVMVPGQAPY--LIPAFPLP-AVSPLGREHTASGAALE-CLPKPLL
S-SSSQSVPALPSPHLDTFLTIFLHDPPMCPLLSP----SFS--------PYPLLGATGF
SEIPS-SVSA------MAP-NLEPPSSVVSQRRDEEKWETQSE-EHPF-LSSRSSSPLQL
DLLQEALSRSWEFSDPTRRDV-CPE

PF12114 // ENSGT00510000046467_0_Domain_1 (1106, 1386)

AEYQSV-------------TGSSGNSNSHFM----
--A------------GELSMVLLRQES---------------------------------
---------------------------------------------------PSGTGSAAS
GSSDSSIYFATSDFSSEITPNGQQSQDCSQRKETLPAVAEESIWRMIERTPECVLMTYQV
PERVKE--IVLKEDLAKLESMRRQQPQFSHGQREELAQVHSWVQSQTVPQDIDIRGCVTC
TNKGSLGD-ATESCGQDAS-----EDTS------------------------

MDPCEDVERSSGKSENPRVNQRHELEGQQASGPEAPENDAAELWSQKCELRSKFVQTTNS
EQQNRNRVSEELIMVVQEMKKYFPSER--HGKPNTLDALNYALLCVHSVQANNESSQILS
Q-NGAPQGDVTLCSLEELATIASGHTSKTT----------------GTFVAVFS-FLSGR
LVHISEQAPSILNCQKEFLESCHFVELLAPQDMRVFYTHTAHAQLPFWNNWTQREASQYE
LAP-VKSFFCRIGGGEAG-EPQRPYCPFRITPNLIHVHSSALME----PEPCCLLLAEKI
HSGYQ------APQIPADRRIFTTTHTPGCVF

PF08447 // ENSGT00510000046467_0_Domain_0 (333, 421)

LEIDERAVPFLGYLPQDLIGTSILAYLH
PEDRPLMLAVHQK-VLKYAGHPPFEHLPIRFCCQNGDYVILDSSWSSFVNPWSRQVSFII

ENSGT00510000046467_0_Linker_0_1 (421, 1071)

GRHIVRTSPPNKDVFATRVKKVSNDDKDTTELQEQIQKLLLQPVHGSK--SGGYGSLGSS
RSQEPQVSLASSSESSGHGVD-----EVPEAPLTLQQICASVNKVKNLGQQLYVESRTKS
AN-KPVLGTGSRRP--------------GDEQKTSSSFQTVKNNS---IYTESCEDLRKV
QRSPSYQQINCIDSVIR--YLKSYHIPVLKRKCISSTNTTSSSSEEDRQSH-RADDIQAL
Q---------------AVSQIPAVPASEMPTKGQSTDAEGGAP---WTLSTVTLSL--DT
SQCSSSSVLVDIPPPDSEELTPAEHIP--------LACEPW-TLST----HPAPLAAEAF
KHSGLTKAVLSAHTQKEEQSYVDKFREKILSSPYSSYLQQESRS--K-AKYLYVQG-GSA
SRPTRSAGCKKGKHKRKKPLVWSDDRSA------KDHFCPH---------QDGQPWCPSS
ASCPHASGPSL-PATVMVPSPAPC--LVPALPLP-ATTSLGREHEALITVLP-RLPEPPL
P-SSLQYFPALPSAYFDTFVNIFLHDPSLSPLSSL----SFS--------PYPFLGAAPS
SEILSSV-SA------VAP-NPGPLSSTINPRSREEKWETRNE-GHPL-I

PF12114 // ENSGT00510000046467_0_Domain_1 (1071, 1387)

NSGSSSMLQL
DLLQEDRPRSCASPETV-----------CGV-------------RGSSGTEIDGFT----
--I------------KKPSIASLHS-----------------------------------
-------------------------------------------------VSPPGTGPAAS
GSSGSSINFAPSDDSSEISENGQQSQDI-QEKGTFPKLAEESIWRMIKQTPDHILMTYQV
PERVKE--IVLKEDLEKLESMRRQQPQFSRGQREEIANVHSWIHSQAIPREIDTQGCVTC
GHRDSAGDAADPMVRIQQKQQ--PSDSEGPALPPQTCWTAPPPCDSL-----

MEPRGDLETPRGEPPGTGGRGA----E-----DEALGEESGERWSPEFHLQRKLAESSHS
EQQDRNRVSEELIMVVQEMKKYFPSER--RNKPSTLDALNYALRCVHSVQANGEFFQILS
Q-NGAPQADVTMYSLEELATIASEHTSKNT----------------DTFVAVFS-FLSGR
LVHVSEQAALILNRKKDVLASSHFVDLLAPQDVRVFYAHTARAQLPFWNNWTQRAAPRYE
CAP-VKPFFCRIRGGEDR-KQEKRHSPFRIIPYLIYVHRPGQPESE--SEPCCLTVVEKI
HSGYE------APRIPVNKRIFTTTHTPGCVF

PF08447 // ENSGT00510000046467_0_Domain_0 (333, 421)

LEVDERAVPLLGYLPQDLIGTSILSYLH
PEDRSLMVAIHQK-VLKYAGHPPFEHSPIRFCTQNGDYIILDSSWSSFVNPWSRKVSFII

ENSGT00510000046467_0_Linker_0_1 (421, 1180)

GRHKVRTSPLNEDVFATKIKKTNNNDKDVTELQEQIYKLLLQPVHVSV--SSGYGSLGSS
GSQEQLVSIASSSEASGHCVE-----ETKAEQMTLQQVYASVNKIKNLGQQLYIESMTKS
SF-KPVTGTRTELNGGGESAN-----DGGEYKTFTSFHQTLKNNS---VYTEPYEDLRND
EHSPSYQQINCIDSVIR--YLKSYNIPALKRKCISCTNTTSSSSEEDKQNH-KADDVEAL
Q---------------AGLQISTIPKSEMPTNGPSIDAGGGAP---QILSTAVLSLGSGI
SQCGYSSTIVHVP-PETA-----RDAT--------LVCEPW-TLNM----QPAPLTSEEF
KHVGLTAAVLSAHTQKEEQNYVDKFREKILSSPYSSYLQQESRS--K-AKYSYFQG-DYT
SKQTQLAGCRKGKHKRKKLPEPPDSNSS------NAGSGP-----HRGARQNAQPCCPST
ASSLHTLGPTF-PPAAMVPSQAPY--LVPAFPLP-AATCPGREYAVPGTVPE-GLHGPPL
S-KDLQPYPAFPSPYLDTFMTVFLPDPPVCPLLSP----SFF--------PCPFLGATAS
SAISPSMSSA------MTP-TLDPPASVTNQRREEEKWEAQSE-GHPF-ITSRSSSPLQL
NLLQEEMPRRSESPDQMRRNT-CPQAEYQCV-------------AGNSSSESSPAT----
--T------------GALSMGSPPRENPSHPTASTLSMG

PF12114 // ENSGT00510000046467_0_Domain_1 (1180, 1388)

SPPSGTPSH---------PTA
SVLSTGSPPCESLSGTGSA---------------------------------------AS
GSSDSSIYFTSSVYS-KISQNGQQSQDV-QKKETFPNDAEESIWRMIRQTPECVLMTYQV
PERVKE--VVLKEDLEKLESMRQQQPQFSHGQKEELAKVYNWIQSQTVPQEINIQACVTC
ENEDSADG-AATSCGQALA-----EDSS------------------------

MDPCEDRHAL------------------------------QGPWGSGAPLHRTEGDTSRS
-EQDRKRVSEELKMVVQEMKKYLPVER--HSKPSTLDALNYALRCVHSVQANSEFFHILS
G-NGFPEIDMTMYGPEELATVAAEHTSKNT----------------DTFVAVFS-FLSGR
LVHISEQSALILKCKKDFLESSHFVDLLAPQDVRVFYMHTARAQLPLWNSNGLMPG----
----------YVRGGG--REQEKHYSPFRIIPYLVHAHSSAHPE----PEPCCLALVEKT
HSGYE-----------VDKRIFTTTHIPGCVF

PF08447 // ENSGT00510000046467_0_Domain_0 (333, 421)

LEVDERAVPLLGYLPQDLIGTSILAYLH
PEDCPLMVAIRQK-VLKYAGHPPFEHSPVRFCVQNGDFIVLDSSWSSFVNPWSRKVSFII

ENSGT00510000046467_0_Linker_0_1 (421, 1260)

GRHKVRTGPLNEDVFATRIKKMNNNDKDVTELEKQIHRLLLQPVHGSA--SSGYSSLGNS
GSQEQQVSVASSSESSGHCVD----------AMTLQQVYAIVNKIKNLGQQLYIESMTKS
PV-QPMMGACAGPPGGGES-------------ATFSSSQMLNNKN---MCTESCEGLRKD
QHSPSYQQIHCIDSVIR--YLKSCHVPVLKRKCVSRTNTASSSS-EDRQHH-SMDSAQAL
Q-----------------------GDSKVPENIRPTAVEGGAT---QTVSTTALSLASDT
SRCSCSSTLIHIPPLESAS-------------------NIW-AKR--------------G
KKQMKARGSLSAHTQKEEQDCVDGFRERILSSPYSCQLLKISHSR-------VLFS-CSA
SKQSRSAGCKEVRHKRKKLPMLLSGSSL------DASMCPL----NKQLLQDVWPWCPPA
APAPQAPGLALPSTVTTLPSQASH--LLPALGLP-ALAFLGAGDPAACGTAPVHLPKPPC
R-SGLHTLPAFPAPHLGTFVTILLHSTPICPPWSP----SS---------PHLSLGASGS
SEMLPAA-SA------VAP-DLEPPS-VDSQGRVEGTWEDQSE-ESGH-MNLRSSSPLQL
NL-QEEMPGSWAPPDPARRDI-TPEAECART-------------TAGPASL---------
---------------G--------------------------------------------
---------------------------------------------------QVSSDLPL

PF12114 // ENSGT00510000046467_0_Domain_1 (1260, 1366)

T
GSSASNIHFTSSDYSSEISEGGQPSQGI-QRKEAHPTLAEDAIWRMTEQTPQCILMTYQV
PQRVKE--VVLKEDLEKLESRRQQQPRFSPGQKEELAKVHSWIQGQSGPQ----------
----------------------------------------------------

------------------------------------------------------------
------------MMMIQEMKRCLPEEKRNSNKPSTISALNYALQCVQQVQANNDFFQALN
D-RRAFQADVVTYSIEELVAVASEHTPKNT----------------DTFVAVFS-LLSGR
IVHISEQAASILNCKKKVLDSSRFVELLVPQDVSVFYTHTDQSHLPLWNMENQT-ASPYE
YAQ-VKSFFCRIKGGKDQ-EQEARCYPFRITPYLVHVCTSVHVD----AESCCLALAEKI
HSGYE------APRIPMDKRIFTTTHTPGCVF

PF00989 // ENSGT00510000046467_0_Domain_0 (333, 419)

LDIDDRAVPLLGYLPQDLIGTSILMYLH
PEDRPLMITIHRK-ILKFAGQPPFEHLPIRFCTQNGDYVILDTSWSSFVNPWSRKVVF

ENSGT00510000046467_0_Linker_0_1 (419, 1192)

II
GRHKVRTSPLNEDVFAPRSKETSSVEKEIRELQGQIYKLLLQPVHSNV--SSGYGSLGSS
GSYEHYISIASSSDSNGNCAE------ETQEPMTLQQVCADVNRIKNLGQQLYIASRSKP
QNAS-EQAVSSEVLG-------------GKSHPASCFLQTLRGDST-EPGNTFYDDPKKT
PHIPSYQQINCVDSIIR--YLESCSIPALKRKCKSSANTSSSSSEDDKQVQQSQQEVRAL
E---------------------VSAGLEETLKDQTTAGMVGAPLADLTLSNKAPSVISVT
SQCSYSSTIVHVPHPESEVTTMEDAA------VGSEQVEPP-PVNA----QSLTVLPEDL
KPVGLTKETLSAHTQKEEQNYVDKFRQRVLLSPFRTYLQQGSGSN---NRHSCGQG-DSP
SKQMSPASYKKGKHGKFKRQKPQRQCLDSHSSSKNRN--SL---PCEKRRNQKQLFSPSE
VSYLRSSSLNVHPPVG-FP---AYSNPVSTFPT-----SSGGEQLALRSLQPQSMSSSQL
C-CGTQSYPVFYPPSIGTFMAVFFQGFPMYAQMPQHV---FLPSPPCVYPPSSYPCTTLP
PAPPPCAPSP------VAPPSVDQPFPASPHSSLEDQQEGQCDQALLL-SSSRSSSPLQL
NLLQEELPKPMELSISADVKP-HAEDK--HD-----------------------------
--------------------------------------------NDPEDSG

PF12114 // ENSGT00510000046467_0_Domain_1 (1192, 1386)

NSAA-----
LEFPDRALYEDSQLGSGSAASGSGSALSASLGS----------------SFNETSGHGTE
---------------------E-GNREA-EEKGTAYKSKHESAWVMMDHTPERFLMNYQM
PNRIKE--EVLKQDLEKLAVMQKQQPWFTDGQKEELAEVHSWIRTQTVPLQISTQGCVTC
DSREASCEAA-------VAAD--SMENKGEPPPVL-----------------

MDPCGNPAVPGGDCPQTRGPGL------------------QGSSGQEGPLQGICVDSSHS
EHEDRNRMSEELIMVVQEMKKYFPAER--HTKPSTLDALNYALRCVHSVQANSEFFQSLS
P-RGARQAEATVYNLEELTSLASEHTSKNT----------------DTFVAVFS-FLSGR
LVHISEQAAWILNSKKGFLKSLHFVDLLAPRDVRVFYAHTAPTQLPFWNTWTQRAS-QYE
CAP-VKPFFCRICGG-GDREQKRHYSPFRILPYLVHVHSPAQPE----PEPCCLTLVEKI
HSGYE------APRIPVDKRVFTTTHTPGCVF

PF08447 // ENSGT00510000046467_0_Domain_0 (333, 421)

LEVDERAVPLLGFLPQDLIGTSILTYLH
PEDRPLMVAVHQK-VLKYVGHPPFEHSPIRFCTQNGDYVILDSSWSSFVNPWSRKVSFII

ENSGT00510000046467_0_Linker_0_1 (421, 1124)

GRHKVRTSPLNEDVFATRIKKATSHDEDITELQEQIHRLLLQPVHASA--SSGYGSLGSS
GSQEQHISVTSSSESSGHCVE-----EAQQEQMTLQQVYASVNKIKNVGQQLYIESMARS
SV-KPVMETCTEPQGS-------------DEQKDFSSSQTLKNKS---TDTGSGGDLRPE
QHSSSYQQMNCIDSVIR--YLTSYSFPALKRKCISCTNTSSS-SEEAKPNP-EADG--SL
R---------------DTEQLLDIPEQE--TTAPSADAEGGVA---RTLSTAALSMASGV
SQCSCSSTTDHVPPLQSE------SVA--------GACEPW-ALRT----KA-HVTAEGF
KPVGLTAAVLSAHTQKEEQNYVDRFREKILTSPYGCYLQQEGRNH---AKYACVVGAGAT
PKHSRCAGSERRKHKRKKLPTPVDSSSS------SAHLCPH----VRGLLPDVQHWSASV
-TSPCATGLAL-PSALVVPSQTPY--LLSSFPLQ-DMAPQGVGDSAAWGAAAE---CPPL
S-AGPQPVSTFPSAYMGTFMTVLLHNSPLFPLWPA----SFS--------PYPFLGATGP
SQMAPLV-PA------MAP-DLEPTPSDHGPRRVEENWETHSEEEHPF-ISSRSSSPLQL
NLLQEEMPAPSEYADAVRRGA-CPDAKQLCV------------

PF12114 // ENSGT00510000046467_0_Domain_1 (1124, 1379)

-TGNSGSRSPPCA----
--T------------GELATASVQQESS--------------------------------
-------------------------------------------------------SAAAS
GSSASSVHGSGSDYTSEVSENGQRSQDR-QRDRAFSGAAEESIWRMIERTPECVLMTYQV
PERGRD--TVLREDLEKLHSMERQQPQFSSAQKEELAKVRSWIHSRPAPEERQLQRAMSP
VKTE----V-QLVTLQRPVNS--VQQK----TPVEQL---------------

MEPRGDLETPRGEAPGPGGRGA----E-----DKALDEESGERWSPQFHLQRKLAESSHS
EQQDRNRVSEELITVVQEMKKYFPSER--RNKPSTLDALNYALRCVHSVQANGEFFQILS
Q-NGAPQADVTMYSLEELAIIASEHTSKNT----------------DTFVAVFS-FLSGR
LVHISEQAALILNRKKDVLVSSHFVDLLAPQDVRVFYAHTARAQLPFWNNWTQRAAPRYE
CAP-VKPFFCRIRGGEDR-KQEKRHSPFRIIPYLIYVHRPGQPESE--SEPCCLTVVEKI
HSGYE------APRIPVNKRIFTTTHTPGCVF

PF08447 // ENSGT00510000046467_0_Domain_0 (333, 421)

LEVDERAVPLLGYLPQDLIGTSILSYLH
PEDRSLMVAIHQK-VLKYAGHPPFEHSPIRFCTQNGDYIILDSSWSSFVNPWSRKVSFII

ENSGT00510000046467_0_Linker_0_1 (421, 1183)

GRHKVRTSPLNEDVFAAKIKKMNSNDKDVAELQEQIYRLLLQPVHVSV--SSGYGSLGSS
GSQEQLVSIASSSEASGHCVG-----ETKAEQMTLQQVYASVNKIKNLGQQLYIESMTKS
SF-KPVTGTCTERNGGGKSAD-----DGGEYKTFTSFHQTLKNNS---VYTEPYEDLRND
EHSPSYQQINCIDSVIR--YLKSYNIPVLKRKCISCTNTTSSSSEEDKQNH-KADDIQAL
Q---------------AGLQIPTIPKSEMPTNGRSIDAGGGAP---QILSTAVLSLGSGI
SQCSHSSTIVHVP-PETA-----MDAT--------LVCEPW-TLNM----QPAPLTSEEF
KHVGLTAAVLSAHTQKEEQNYVDKFREKILSSPYSSYLQQESRS--K-AKYSYFQG-DYT
SKQTQLASCRKGKHKRKKLPEPPDSSSS------NVGCGPHRGGPHRGARQNAQPCCPST
ASSPHTSGPTF-PPAAMVPSQAPY--LIPAFPLP-AATCPGREYATPGTAPE-GLHGPPL
S-KGLQPYPAFPSPYLDTFMTVFLPDPHVCPLLSP----SFF--------PCPFLGATAS
SAISPSMSSA------MTP-TVDPPASVTNQRREEEKWEAQSE-GHPF-ITSRSSSPLQL
NLLQEEMPRSSESPDQMRRNT-CPQAEYQCV-------------TGNSGSESSPAT----
--T------------GALSTGSPPRENPSHPTASTLSMGSPP

PF12114 // ENSGT00510000046467_0_Domain_1 (1183, 1388)

SGTPSH---------PTA
SVLSTGSPPSESPSGTGSA---------------------------------------AS
GSSDSSMYFTSSVYS-KISQNEQQSQDV-QKKETFPNVAEESIWRMIQQTPECVLMTYQV
PERVKE--VVLKEDLEKLETMRQQQPQFSHGQKEELAKVYNWIQSQTVPQEIDIQACVTC
ENEDSADG-AATSCGQALA-----EDSS------------------------

MEPCGDLETPLGEPPGPGGRAA----E-----DEALGEDFGERWSPEFHLQRKLADPSHS
EQQDRNRVSEELIMVVQEMKKYFPSER--RNKPSTLDALNYALRCVHSVQANSEFFQILS
Q-NGAPQADVTMYSLEELATIASEHTSKNT----------------DTFVAVFS-FLSGR
LVHVSEQAALILNRKKDVLATSRFVDLLAPQDVRVFYAHTARAQLPFWNDWTQR-APRYE
CAP-VKPFFCRIRGGEDR-EQEKRPSPFRIIPYLIHVHHPAQPELE--SEPCCLTVVEKI
HSGYE------APRIPVNKRIFTTTHTPGCVF

PF08447 // ENSGT00510000046467_0_Domain_0 (333, 421)

LEVDERAVPLLGYLPQDLIGTSILSYLH
PEDRSLMVAIHQK-VLKYAGHPPFEHSPIRFCTQNGDYIILDSSWSSFVNPWTRKVSFVI

ENSGT00510000046467_0_Linker_0_1 (421, 1240)

GRHKVRMSPLNEDVFATKIKKMNNNDKDITELQEQIYKLLLQPVHMSV--SSGYGSLGST
GSQEQLVSMASSSEASGQCME-----ETKAEQMTLQQVYASVNKIKNRGQQLYIESRTKS
SI-KPVTGMCTELNG------------GGEYKACTSFHQTLKNNS---MYTEPHKDLRNE
EHSPSYQQINCIDSVIR--YLKSYNIPALKRKCISCTNTTSSSSEEDKQNH-KADDVPAL
Q---------------AGLQIPAIPKPEMPTNARSTDAGGAAP---QILSTTVLSLGSGM
SQCSYGSTTVHIPPPETA-----RDAT--------LMCEPW-TLNM----RPAPLTSEEF
KHVGLTAAVLSAHTQKEEQNYVDKFREKILSSPYSSYLQQESRS--K-AKYAYFQG-DST
SKQTRSAGCRKGKHKRKKLLEPPDSSSS------NTGSGP-----RRGAHLNAQPCCPSA
ASSPHSSGPTF-PPAAMVPSHAPY--LI-----P-AVTCPGREYAAPGTAPE-VLPGPSS
S-KDQQTCPAFPSPYLDTFMTVFLPDPSVCPLLSP----SFF--------PCPFLGVTAC
SAISPSM-SA------VTP-NLDTPPSITNQRREEEKWEAQSE-GHPF-ISSRSSSPLQL
DLLQEEMPRPSESSDEIRRNR-SPQAEY-CV-------------IGNSGSEGSPAA----
--T------------HALSMGSPPRETPSH------------------------------
-----------------------------------P-TA

PF12114 // ENSGT00510000046467_0_Domain_1 (1240, 1388)

GVLSTGSPPRETPSGTGSAAS
GSSDCSIYFTSSAYSSEISQNGQQSQDV-QKKEIFPNVAEESIWRMIRQTPECILMTYQV
PERVKE--VVLKEDLERLESMKQQQPQFSQGQQEELAKVYNWIQSQAIPQEIDVQACVTC
ESADSADD-GATSSGQAED-----CS--------------------------

--------MPRGEAPGPGRRGA----E-----DEALGEESGERWSPEFHLQRKLADSSHS
EQQDRNRVSEELIMVVQEMKKYFPSER--RNKPSTLDALNYALRCVHSVQANSEFFQILS
Q-NGAPQADVSMYSLEELAAIASEHTSKNT----------------DTFVAVFS-FLSGR
LVHISEQAALILNRKKDVLASSHFVDLLAPQDVRVFYAHTARAQLPFWNNWTQRAAARYE
CAP-AKPFFCRIRGGEDR-KQEKCHSPFRIIPYLIHVRHPAQPESE--SEPCCLTVVEKI
HSGYE------APRIPVNKRIFTTTHTPGCVF

PF08447 // ENSGT00510000046467_0_Domain_0 (333, 421)

LEVDEKAVPLLGYLPQDLIGTSILSYLH
PEDRSLMVAIHQK-VLKYAGHPPFEHSPIRFCTQNGDYIILDSSWSSFVNPWSRKVSFII

ENSGT00510000046467_0_Linker_0_1 (421, 1211)

GRHKVRTSPLNEDVFATKIKKMNNNDKDITELQEQIYKLLLQPVHVSV--SSGYGSLGSS
GSQEQLVSIASSSEASGHCVE-----ETKAEQMTLQQVYASVNKIKNLGQQLYIESMTKS
SF-KPVTGTRTEPNGGGESAN-----GGGECKTFTSFHQTLKNNS---VYTEPCEDLRND
EHSPSYQQINCIDSVIR--YLKSYNIPALKRKCISCTNTTSSSSEEDKQNH-KADDVQAL
Q---------------AGLQIPAIPKSEVPTNGRSIDTGGGAP---QILSTAMLSLGSGI
SQCGYSSTIVHVPPPETA-----RDAT--------LFCEPW-TLNM----QPAPLTSEEF
KHVGLTAAVLSAHTQKEEQNYVDKFREKILSSPYSSYLQQESRS--K-AKYSYFQG-DST
SKQTRSAGCRKGKHKRKKLPEPPDSSSS------NAGSGP-----RRGAHQNAQPCCPSA
ASSPHTSSPTF-PPAAMVPSQAPY--LVPAFPLP-AATSPGREYAAPGTAPE-GLHGPPL
S-EGLQPYPAFPFPYLDTFMTVFLPDPPVCPLLSP----SFF--------PCPFLGATAS
SAISPSMLSA------MSP-TLDPTPSVTSQRREEEKWEAQSE-GHPF-ITSRSSSPLQL
NLLQEEMPRPSESPDQMRRNT-CPQAEYQCV-------------TGNNGSESSPAT----
--T------------GALSTGSPPRENPSHPTASALSTGSPPMENPSH---------PTA
TVLSTGSPPS

PF12114 // ENSGT00510000046467_0_Domain_1 (1211, 1388)

KSPSRTGSAASGSGSGQLMFQTPLPGIHYVLSSHGDPPALAS--QSAGIT
GSSDSSIYLTSSVYSSKISQNGQQSQDV-QKKETFPNVAEEPIWRMIRQTPERILMTYQV
PERVKE--VVLKEDLEKLESMRQQQPQFSHGQKEELAKVYNWIQSQTVTQEIDIQACVTC
GNEDSADG-AATSCGQVLV-----EDSS------------------------

--------TPRGEPPGPGGRGA----E-----DEALGEESAERWSPEFHLQRKLAESSHS
EQQDRNRVSEELIMVVQEMKKYFPSER--RNKPSTLDALNYALRCVHSVQANGEFFQILS
Q-NGAPQADVTMYSLEELATIASEHTSKNT----------------DTFVAVFS-FLSGR
LVHVSEQAALILNRKKDVLTSSHFVDLLAPQDVRVFYAHTARAQLPFWNNWTQRAAPRYE
CAP-VKPFFCRIRGGEDR-KQEKRHSPFRIIPYLIYVHRPGQPESE--SEPCCLTVVEKI
HSGYE------APRIPVNKRIFTTTHTPGCVF

PF08447 // ENSGT00510000046467_0_Domain_0 (333, 421)

LEVDERAVPLLGYLPQDLIGTSILSYLH
PEDRSLMVAIHQK-VLKYAGHPPFEHSPIRFCTQNGDYIILDSSWSSFVNPWSRKVSFII

ENSGT00510000046467_0_Linker_0_1 (421, 1180)

GRHKVRTSPLNEDVFATKIKKTNNNDKDVTELQEQIYKLLLQPVHVSV--SSGYGSLGSS
GSQEQLVSIASSSEASGHCVE-----ETKAEQMTLQQVYASVNKIKNLGQQLYIKSMTKS
SF-KPVTGTRTELNGGGESAN-----DGGEYKTFTSFHQTLKNNS---VYTEPYEDLRND
EHSPSYQQINCIDSVIR--YLKSYNIPALKRKCISCTNTTSSSSEEDKQNH-KADDVQAL
Q---------------AGLQISTIPKSEMPTNGPSIDAGGGAP---QILSTAVLSLGSGI
SQCGYSSTIVHVP-PETA-----RDAT--------LVCEPW-TLNM----QPAPLTSEEF
KHVGLTAAVLSAHTQKEEQNYVDKFREKILSSPYSSYLQQESRS--K-AKYSYFQG-DYT
YKQTQLAGCRKGKHKRKKLPEPPDSSSS------NAASGP-----HRGVRQNAQPWCPST
ASSPHTLGPTF-PPAAMVPSQAPY--LVPAFPLP-AATCPGREYAAPGTVPE-GLHGPPL
S-KDLQPYPAFPSPYLDTFMTVFLPDPPVCPLLSP----SFF--------PCPFLGATAS
SAISPSMS-A------MTP-TLDPPASVTNQRREEEKWEAQSE-GHPF-ITSRSSSPLQL
NLLQEEMPRRSESLYQMRRNT-CPQAEYQCV-------------AGNSSSESSPAT----
--T------------GALSMGSPPRENPSHPTASTLSMG

PF12114 // ENSGT00510000046467_0_Domain_1 (1180, 1388)

SPPSGTPSY---------PTA
SVLSTGSPPCESLSGTGSA---------------------------------------AS
GSSDSSIYFTSSVYS-KISQNGQQSQDV-QKKETFPNVAEESIWRMIRQTPECVLMTYQV
PERVKE--VVLKEDLEKLENMRQQQPQFSHGQKEELAKVYNWIQSQTVPQEINIQACVTC
ENEDSADG-AATSCGQALA-----EDSS------------------------

--------MPRGEAPGPGRRGA----E-----DEALGEESGERWSPEFHLQRKLADSSHS
EQQDRNRVSEELIMVVQEMKKYFPSER--RNKPSTLDALNYALRCVHSVQANSEFFQILS
Q-NGAPQADVTMYSLEELATVASEHTSKNT----------------DTFVAVFS-FLSGR
LVHISEQAALILNRKKDVLASSHFVDLLAPQDVRVFYEHTARAQLPFWNNWPQRAAARYE
CAP-VKPFFCRIRGGEDR-KQEKRHSPFRIIPYLIHVHRPAQPQSE--SEPCCLTVVEKI
HSGYE------APRIPVNKRIFTTTHTPGCVF

PF08447 // ENSGT00510000046467_0_Domain_0 (333, 421)

LEVDERAVPLLGYLPQDLIGTSILSYLH
PEDRSLMVAIHQK-VLKYAGHPPFEHSPIRFCTQNGDYIILDSSWSSFVNPWSRKVSFII

ENSGT00510000046467_0_Linker_0_1 (421, 1167)

GRHKVRTSPLNEDVFATKIKKMNNNDKDITELQEQIYKLLLQPVHVSV--SSGYGSLGSS
GSQEQLVSIASSSEASGHCVE-----ETKAEQMTLQQVYASVNKIKNMGQQLYIESMTKS
SF-KPVTGTCTEPNG------------GGECKTFTSFHQTLKNNS---VYTEPCEDLRND
EHSPSYQQINCIDSVIR--YLKSYNIPALKRKCISCTNTTSSSSEEDKQNH-KADDVQAL
Q---------------AGLQIPAIPKSEMPTNGRSIDTGGGAP---QILSTAMLSLGSGI
SQCGYSSTIVHVPPPETA-----RDAT--------LFYEPW-TVNM----QPAPLTSEEF
KHVGLTAAVLSAHTQKEEQNYVDKFREKILSSPYSSYLQQESRS--K-AKYSYFQG-DST
SKQTRSAGCRKGKHKRKKLPEPPDSSSS------NAGSGP-----RRGAHQNAQPCCPSA
ASSPHTSSPTF-PPAAMVPSQAPY--LVPAFPLP-AATSPGREYAAPGTAPE-GPHGPPL
P-EGLQPYPAFPFPYLDTFMTVFLPDPPVCPLLSP----SFF--------PCPFLGATAS
SAISPSMSSA------MSP-TLDPPSSVTNQRREEEKWEAQSE-GHPF-ITSRSSSPLQL
NLLEEEMPRPSGSPDQMRRNM-CPQAKY-CV-------------TGNNGSESSPAT----
--T------------GALSTGSPPRE

PF12114 // ENSGT00510000046467_0_Domain_1 (1167, 1386)

NPSHPTASTLSMGLPPSRTPSH---------PAA
SVLSMGSPPSESP---------------------------------------SRTGSAAS
GSSDSSIYFTSSVYSSKISQNGQQSQDV-QKKETFPNVAEEPIWRMIRQTPERILMTYQV
PERVKE--VVLKEDLEKLESMRQQQPQFSHGQKEELAKVYNWIQSQTITQEVDIQACVTC
ENEDSADG-AATSCGQILV-----EDSS------------------------

-----------------------------------------------------------S
DRLDWGQSHKDLMVMIQEIKKCLPEEKRSSSKPSTISALNYALRCVQQVRANNEFFQALS
D-RRVFQMDVMTYSIEELVTVASEHTPKNN----------------DTFVAVFS-LLSGR
ILHISEQAASILNHKKKVLESSRFVELLAPQDASVFYAHTDQSHLPLWYTESQTVASLYD
YAQ-VKSFFCRIRGGKDQ-EQEMHWYPFRITPYLVHVCTSVHVD----AESCCLALAEKI
HSGYE------APRIPMDKRIFTTTHTPGCV

PF08447 // ENSGT00510000046467_0_Domain_0 (332, 429)

FLEIDDRAVPLLGYLPQDLIGTSILMYLH
PEDRPLMITIHRK-ILKFAGQPPFEYLPIRFCTQNGDYVILDTSWSSFVNPWSRKVAFII
GRHRVRTSPLNEDVFATRGQETSSVEKEIKELQGQIYKLLLQPVHSNV--SSGYGSLGSS
GSYEHYISVASSSDSNGNCAE------ETQEPVTLQQVCADVNRIKNLGQQLYIASRSKP
QNGN-EQPMGSEVLEG----K------------------TLRSDSTEELGNALYDDSKKT
PHVPSYQQINCVDSIIR--YLESCSVPVLKRKSKSSTNTSSSSDGD-KKN----QEIGAL
G---------------VNSQTPVFADQEEMLKKQTNEGIVGAPLPDLTLSNKSLSVGSAS
SQCSYSSTIVHVPHPESVPCFPLRCN-----------FTTY-FSNA----PNPVTVAEEL
KPVGLTKEALSVHTQKEEQNYVDRFRRRILLSPFRTCLQWDSRSN---NGHSYDQG-NSP
SKEMTPTSCKNGKKGKFKHWKPQRQSSDRRSRSKNRN--SF---PCEKRRIQKQSLSPSE
MSCLRSSSTNCFPPVG-FP---VYSDALSSFQA-----SSIGEELAIYSTKPEPTSLSQL
C-CGAPSIPALSPPNMGMFMAAFFHNFPIYAQMPQYA---FLPSPQNVYLPSSYPCTTLP
PAPPPSAPSA------IAPVSVGQSYPAFSAASTEEQPEGQHGWALQL-SSSRSSSPLQL
NLLQEELPESAEPLVNADVKV-YAEAK--CG-------------TNNTGGRETTFEPMGT
CSSAELVLSKSHSALAMLSLFFSPLNCESHSLCGELKQRKPPGDNSREDSGNSASSHCAS
CECTDRLLREDSQSGAGSAASA--------------------------------------
GSRKSSKYFASNDSSE-TSKTD-TNQEA-KEKQTSHKSKHESAWVTMDRTPEQVLMTYQM
PNRIKE--EVLKEDMEKLIVMRQQQPWFSDRQKRELAEVHTWLQTQTVPLQINIQGCVTC
DIREATCEAA-------MADD--NM---------------------------

MDPCEDRHAL------------------------------QGPWGSGAPLHRTEGDTSRS
-EQDRKRVSEELKMVVQEMKKYLPVER--HSKPSTLDALNYALRCVHSVQANSEFFHILS
G-NGFPEIDMTMYGPEELATVAAEHTSKNT----------------DTFVAVFS-FLSGR
LVHISEQSALILKCKKDFLESSHFVDLLAPQDVRVFYMHTARAQLPLWNSNGLMPG----
----------YVRGGG--REQEKLYSPFRIIPYLVHAHSSAHPE----PEPCCLALVEKT
HSGYE-----------VDKRIFTTTHIPGCVF

PF08447 // ENSGT00510000046467_0_Domain_0 (333, 421)

LEVDERAVPLLGYLPQDLIGTSILAYLH
PEDCPLMVAIRQK-VLKYAGHPPFEHSPVRFCVQNGDFIVLDSSWSSFVNPWSRKVSFII

ENSGT00510000046467_0_Linker_0_1 (421, 1260)

GRHKVRTGPLNEDVFATGIKKMNNNDKDVTELEKQIHRLLLQPVHGSA--SSGYSSLGNS
GSQEQQVSVASSSESSGHCVD----------AMTLQQVYAIVNKIKNLGQQLYIESMTKS
PV-QPMMGACAGPPGGGES-------------ATFSSSQMLNNKN---MCTESCEGLRKD
QHSPSYQQIHCIDSVIR--YLKSCHVPVLKRKCVSRTNTASSSS-EDRQHH-SMDSAQAL
Q-----------------------GDSKVPENIRPTAVEGGAT---QTVSTTALSLASDT
SRCSCSSTLVHIPPLESAS-------------------NIW-AKR--------------G
KKQMKARGSLSAHTQKEEQDCVDGFRERILSSPYSCQLLKISHSR-------VLFS-CSA
SKQSRSAGCKEVRHKRKKLPMLLSGSSL------DASMCPL----NKQLLQDVWPWCPPA
APAPQAPGLALPSTVTTLPSQASH--LLPALGLP-ALAFLGAGDPAACGTAPAHLPKPPC
R-SGLHTLPAFPAPHLGTFVTILLHSTPICPPWSP----SS---------PHLSLGASGS
SEMLPAA-SA------VAP-DLEPPS-VDSQGRVEGTWEDQSE-ESGH-MNLRSSSPLQL
NL-QEEMPGSWAPPDPARRDI-TPEAECART-------------TAGPASL---------
---------------G--------------------------------------------
---------------------------------------------------QVSSDLPL

PF12114 // ENSGT00510000046467_0_Domain_1 (1260, 1366)

T
GSSASNIHFTSSDYSSEISEGGQPSQGI-QRKEAHPTLAEDAIWRMTEQTPQCILMTYQV
PQRVKE--VVLKEDLEKLESRRQQQPRFSPGQKEELAKVHSWIQGQSGPQ----------
----------------------------------------------------

MDPCEDVERSSGKSENPRGNQRHELEGQQASGPEAPENDAAELWSQKCELRSKFVQTSNS
EQQNRNRVSDELITVVQEMKKYFPSER--HGKPNTLDALNYALLCVHSVQANNESFQILS
Q-NGAPQGDVTLCSLEELATIASGHTSKTT----------------GTFVAVFS-FLSGR
LVHISEQAPSILNCQKEFLESCHFVELLAPQDMRVFYTHTAHAQLLFWNNWTQREASQYE
LAP-VKSFFCRIGGGEAG-ELQRPYCPFRITPNLIHVHSSALME----PEPCCLLLAEKI
HSGYQ------APQIPADKRIFTTTHTPGCVF

PF08447 // ENSGT00510000046467_0_Domain_0 (333, 421)

LEIDERAVPFLGYLPQDLIGTSILAYLH
PEDRPLMLAMHQK-VLKYAGHPPFEHLPIRFCCQNGDYVILDSSWSSFMNPWSRKVSFII

ENSGT00510000046467_0_Linker_0_1 (421, 1132)

GRHKVRTSPLNKDVFATRVKKVSNDDKDTTELQEQIQKLLLQPVHGSK--SSGYGSLGSS
GSQEPQVSLASSSESSGHGVD-----EVPEAPLTLQQICASVNKIKNLGQQLYVESRAKS
AN-KPVSGTRSGRP--------------GDEQKTSSSFQTVKNNS---MYTESCEDLRKV
QRSPSYQQINCIDSVTR--YLKSYHIPVLKRKCISSTNTTSSSSEEDRQSH-RADDIQAL
Q---------------AISQIPTVPASEMPTKGQSTDAEGGAP---WTLSTVTLSL--DT
SQCSSSSVLVDIPPPDS-ELTPAEHVP--------LACEPW-TLST----HPAPLAAEAF
KHSGLAKAVLSAHAQKEEQSYVDKFQEKILSSPCSFYLQQESRS--K-AKYLYVQG-GSA
SRLARSAGCRKGKHKRKKPLMWSDGRSA------KDHFCPH---------QDGQPWCPSS
ASCPHASGPSL-PATVMVPSPAPC--LVPALRLP-ATTSLGREHEALITVLP-RLPEPPL
P-SSLQYFPALPSAYFNTFVNLFLHDPSLSPLSSL----SFS--------PYPFLGAAPS
SEILSSV-SA------VAP-NPGPLSSTINPRSREEKWETRNE-GHPL-INSGSSSMLQL
DLLQGDRPRSCASPETV-----------CGV-------------RGSSGTE

PF12114 // ENSGT00510000046467_0_Domain_1 (1132, 1398)

IDGFT----
--I------------KKPSIASLHS-----------------------------------
-------------------------------------------------VSPPGTGPAAS
GSSGSSINFAPSDDSSEISENGQQSQDI-QKKGTFPKLAEESIWRMIKQTPDRILMTYQV
PERVKE--IVLKEDLEKLESMRRQQPQFSRGQREEIANVHSWIHSRAIPREIDTQGCVTC
GHRDSAGDAADPTVRIQQKQQ--PSDSEGPALPLQTCWTAPPPCDSLRTLAA

MDPCEDLEMPGGQTPDPGRLEA--------------GGE-AERWSPQFQLQRKFVESSNR
EQQDRNRVSEELVMVVQEMKKYFPSER--HNKPSTLDALNYALRCVHSVQANSGFFQTLS
Q-NGASQADVTTYSLEELATIASEHTSKNT----------------DTFVAVFS-FLSGR
LVHISEQAALTLNCKKGCLESSHFVDLLAPQDVRVFYTHTARAQLPFWNNWTQRAASQCE
PAL-VKSFFCRIRGGEDRRKQEKYYYPFRIIPYMIHVRSSAQPE----SEPCCLTLVEKI
HSGYE------APRIPVDKRIFTTTHSPGCV

PF00989 // ENSGT00510000046467_0_Domain_0 (332, 420)

FLEVDERAVPLLGYLPQDLIGTSILTYLH
PEDRSLMIAVHQK-VLKYAGHPPFEHSPIRFCTQNGDYIILDSSWSSFVNPWSRKVSFI

ENSGT00510000046467_0_Linker_0_1 (420, 1128)

I
GRHKVQTSPLNEDVFATRIKKMNNNDKDITELQEQIHKLLLQPVHVSA--SSGYGSLGSS
GSQEQHVSAASSSESSGHCAE-----EPRKEPMTLQQVYASVNKIKNLGQQLYIESMTRS
SV-KPVTGTCTEPLSA------------DEQKAFS-SFQTLRNNS---LCTESCEDLRKG
QHSPSYQQINCIDSVIR--YLKSYNIPALKRKYVSCANTTSSSSEDDKQNL-KADDVQAL
H---------------------AIPKSEMPANEWSTDAEVGAP---RTLSTAALSLGSGI
SQCSYSSTMVHVPPTEAA-----EDAT--------LACEPW-TLNT----QPVPLTSDEF
KPIGLTKAVLSAHTQKEEQNYVDKFRERILSSPYSSYLQQESRN--E-AKYSFVPG-DST
SKQTRSAGCKKGKHKRKKVPAPSASSSS------DAGSRPH----TRGTLGRTQPQYPPA
ASCPHALGLSF-PSSVMIPSQAPY--LTPAFPLP-PVTSLGRGDAAVGTALD-HLPEPPS
A-SGLQPLPAFPPPYLDTVMTIFLHSPPVCPLLSS----SFF--------PYPFLGATDS
SEIPPPT-AA------VAP-YPEPSPSVTIQTGVEEQWETGGE-GHPF-ISSRSSSPLQL
NLLQEEMPKSSEFSDHMKRDI-CPKPEYQCV-------------TGK

PF12114 // ENSGT00510000046467_0_Domain_1 (1128, 1385)

SENKNSRPP----
--A------------SELSPLSPHK-----------------------------------
----------ESQS----------------------------------------GARFLI
GSSDSSTYFASSDYSSGISPNGQQSQDT-QKKEAFPSSAEEPIWRMIREVPESILMTYQV
PERVKE--VVLKEDLEKLERMRQQQPRFSHGQKEELAKIYSWVQSQTVPQEADIQDCATG
ENKGSIDA-AAESCGQDPA-----EDSS------------------------

---------------------------------------------------------SYS
ERQDRNRVSEELITVVQE-KKYFPSGR--HHKPSTLDALNYA-RCVHSVQASSEFFQILS
P-NGAPQADVTMYSLEELASMAAEHTSKNT----------------DTFVAVFS-LVSGR
VVHISEQAPSILSCRRESLASSHFAELLAPQDVRVFYTHTAHAQLPVWSSWTQRAS-QYE
LAP-VKSFFCRIREGGSR---GQRYAPFRVIPYLIHVRPQSEPE----PEPCCLALAEKM
HSGYE------APRIPVDKRIFTTTHTPGCV

PF08447 // ENSGT00510000046467_0_Domain_0 (332, 429)

FLEIDDRAVPLLGYLPQDLVGTSILAHLH
PEDRALMVAVHQE-VLRSAGRAPSEHRAVRFCTHNGDYVILDSSWSGFVDPWSRKVSFIM
GRHKVRTSPLNEDVFAARISKMDNNDKDITELQEQIHKLLLQPVHGST--SSGYSSLGSS
GSQEQHVSVASSGESSGPGAE-----DAQKEPLTLQQVYASVNKIKTLGQQLYIESMTKP
PN-KPAVGTRTGRPS--------------GEQEAFSPVRPWKNES---VRTESCQGLRKD
QHRPSYQQINCIDGVIR--YLRSCRTPALKRKCISCTNTASS-SEDDRQAH-KADDAHAV
R--------------------------EVPARGRSTGAEGGAS---RTEARAAPSLGSGI
SQCSYSSTMVHAPPPEPAEPTPAEDAA--------PACEPW-APGT----LPAPLTAEEF
QHVGLTTAVLSAHTQREEQDYVDRFREKMLSSPYSSYLQHEGRG--Q-ATCSDGQG-ASS
PGQARSPGGKKGKHKRKKLPEPLGSRCA------EDACCPH----FGRDVQDAQPWSLPP
ASPLHAPGLAFPAAVVAPGQALPY--LMPALPLP-TVAPGGH------------------
----CPPFPDVPSPYAETFLTIVLPGPSVCPLWAP----SFS--------PYLYLGAAGP
SETPPSV-PT------AAP-SVEPPFPVTTQRGAGQSWEMQSA-GCPG-PSSRGSSPLQL
ALLQEDRPPSCESAEQVR------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------

MEPRGDLETPRGEPPGPGGRGA----E-----YEALGEESGERWSPEFHLQRKLAESSHS
EQQDRNRVSEELIMVVQEMKKYFPSER--RNKPSTLDALNYALRCVHSVQANGEFFQILS
Q-NGAPQADVTMYSLEELATIASEHTSKNT----------------DTFVAVFS-FLSGR
LVHVSEQAALILNRKKDVLASSHFVDLLAPQDVRVFYAHTARAQLPFWNNWTQRAAPRYE
CAP-VKPFFCRIRGGEDR-KQEKRHSPFRIIPYLIYVHRPGQPESESEPEPCCLTVVEKI
HSGYE------APRIPVNKRIFTTTHTPGCVF

PF08447 // ENSGT00510000046467_0_Domain_0 (333, 421)

LEVDERAVPLLGYLPQDLIGTSILSYLH
PEDRSLMVAIHQK-VLKYAGHPPFEHSPIRFCTQNGDYIILDSSWSSFVNPWSRKVSFII

ENSGT00510000046467_0_Linker_0_1 (421, 1164)

GRHKVRTSPLNEDVFATKIKKTNNNDKDVTELQEQIYKLLLQPVHVSV--SSGYGSLGSS
GSQEQLVSIASSSEASGHCVE-----ETKAEQMTLQQVYASVNKIKNLGQQLYIESMTKS
SF-KPVTGTRTELNGGGESAN-----DGGEYKTFTSVHQTLKNNS---VYTEPYEDLRND
EHSPSYQQINCIDSVIR--YLKSYNIPALKRKCISCTNTTSSSSEEDKQNH-KANDVQAL
Q---------------AGLQIPTIPKPEMPTNGRSIDAGGGAP---QILSTAVLSLGSGI
SQCGYSNTIVHVP-PETA-----RDAT--------LVCEPW-TLNM----QPAPLTSEEF
KHVGLTAAVLSAHTQKEEQNYVDKFREKILSSPYSSYLQQESRS--K-AKYSYFQG-DYT
SKQTQLAGCRKGKHKRKKLPEPPDSSSS------NAGSGP-----HRGARQNAQPCCPST
ASSPHTSGRTF-PPAAMVPSQAPY--LVPAFPLP-AATCPGREYAAPGTVPE-GLHGPPL
S-KDLQPYPAFPSPYLDTFMTVFLPDPPVCPLLSP----SFF--------LCPFLGATAS
SGISPSMSSG------MTP-TLDPPASVTNQRREEEKWEAQSE-GHPF-ITSRSSSPLQL
NLLQEEMPRRSESPDQMRRNT-CPQAEYQCV-------------AGNSGSESSPAT----
--T------------GALSTGSP

PF12114 // ENSGT00510000046467_0_Domain_1 (1164, 1386)

PRENPSHPTASTLSMGSPPSGTPSH---------PTA
SVLSTGSPPSESPSGTGSA---------------------------------------AS
GSSDSSIHFTSSVYS-KISQSGQQSQDV-QKKETFPNVAEESIWRMIRQTPECVLMTYQV
PERVKE--VVLKEDLEKLESMRQQQPQFSHGQKEELAKMYNWIQSQTLSQEINIQACVTC
ENEDSADG-AAISCGQALA-----EDSS------------------------

--------TAGKKPADLKGQAPKDQ-------APGRWAEGLELWSPEFQLQRTSLDDSHS
EQQDWKRVSEELVMVVQEMKKYFPSER--HKKPSTLDALHYALRCVHSVQANSEFFQILS
P-NGTPQADVTKYSLEELATIASEHTSKNT----------------DTFVAVFS-FLSGR
LVHISEQATLILNCKKDFLASSHFVDLLAPQDVRVFYMHTAHAQLPFWNNWTRRAASQYE
YAP-VKSFFCRIHGGEDR-EKRKYYSPFRIIPYLIHVHSSAQPE----WEACCLTLVEKI
HSGYE------XXXXXXXXXXXXXXXXXXXXX

PF08447 // ENSGT00510000046467_0_Domain_0 (333, 429)

XXXXXXAVPLLGYLPQDLIGTSILKYLH
PEDRSLMVALHQK-ILKYVGHPPFEHSPIRFCTQNGDYIILDSSWSSFVNPWSRKVSFII
GRHKVRTGPLNEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPVHASA--SSGYGSLGSS
GSQEHHISVASSSECSGHGAE-----EPQKEPMTLKQVYASVNKIKNLGQQLYIESMRSS
-I-KPVXXXXXXXXXX------XXXXXXXXEQKASSSLQTLQNNS---MYTEPYEDLRKD
QHSPSYQQINCIDSVIR--YLKSYXXXXXXXXXXXXXXXXXXXXX-XXXXX-XXXXXXXX
XX--------------XVSQIPAIPESKMPTNGQSTDAEGGVP---RTMSTTALNLGSGI
SQYSYSSTIVHVPPVESA-----ENAT--------LACEPW-TLNT----QPAPLASEEL
KHVGLTKAVLSAHTQKEEQNYVDKFREKILSSPYISYLHQESRS--K-AKYSYVQG-EST
SKQTSSAGYKKGKHKRKKLPVLWDSNSQ------SPTSVP-----SRGELQNMQPWDPPA
ASSPHASGLAF-PSAMMIPSQVPY--LIPAFPLP-SMSSLEREHAASGAVLE-CLPKPLL
P-SGLQSFPAFPSPNLDTFMTIFLHGPAISPLSSP----SFS--------PYSFLGATGS
PDMPPSV-ST------VTP-DLEPPFSGINQRRVQEKWETQSE-DHPF-INSRSSSPLQL
NLLQEEMPRSSESSDWMKKDT-CL--EYQHV-------------TGNRGNKIHHPA----
--A------------GKLSAVLHK-ES---------------------------------
------------PSGTGSTASXXXXXXXXX------------------------------
---------XXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXDKE--VVLKDDLQKLERMRQQQPKFSLGQKEELAKVRSWIQSQTLPQEMGIQGCDAC
ENKNSVDA--AESSGQDPA-----EDSS------------------------

MDPCGDPAVPGGDCPQTRGPGL------------------QGASGQEGPLQGTCVDSSHS
EHEDRNRMSEELIMVVQEMKKYFPAER--HTKPSTLDALNYALRCVHSVQANSDFFQSLG
P-RGAHQADVTVYSLEDLTALASEHTSKNT----------------DTFVAVFS-FLSGR
LVHISEQAALILNSKKGFLKSLHFVDLLAPQDVRAFYAHTAPTQLPFWNNWTQRAS-QYE
CAP-AKPFFCRICGGGDR--EKRHYSPFRILPYLVHVHSSAQPE----PEPCCLTLVEKI
HSGYE------APRIPVDKRIFTTTHTPGCVF

PF08447 // ENSGT00510000046467_0_Domain_0 (333, 421)

LEVDERAVPLLGYLPQDLIGTSILTYLH
PEDRPLMVAIHQK-VLKYAGHPPFEHSPVRFCTQNGDYVILDSSWSSFVNPWSRKVSFII

ENSGT00510000046467_0_Linker_0_1 (421, 1106)

GRHKVRTSPLNEDVFATRIKKAASNDKDIAELQEQIHKLLLQPVHASA--SSGYGSLGSS
GSQEQHVSITSSSESSGHCPE-----EGQHEQMTLQQVYASVNKIKNVGQQLYIESMARS
SV-KPVAETCVEPQGG-------------DEQKDFSSSQTLKNKS--TTDTGSGGDLQQE
QPSSSYQQMNCIDSVIR--YLTSYSLPALKRKCISCTNTSSS-SEEAKPIP-EADS--SQ
R---------------DTEQLLDIQKQE--TTGPSTDIEGGAA---RTLSTAALSVASGI
SQCSCSSTSGHVPPLQSE------SVA--------MACKPW-ALRT----KASHLAAGGF
KHMGLTAAVLSAHTQKEEQNYVDRFREKILTSPYGCYLQQESRNR---AQYSCVQ-AGST
AKHSRCAGSERQKHKRKKLPAPVDTSSP------SAHLCPH----VTGLLPDEQYWSPSA
SPAPLGAGLAF-PSALVVPSQTPY--LIPSFPLQ-DMASQGVGDSAAWGAAAG---CPPL
S-AGPQAVAAFPSTYMDTLMTIFLHNAPLFPLWPP----SFS--------PYPSLGAAWS
SELAPLV-PA------MAP-NPEATTSDHSQRRVEENWEAHSE-ELPF-ISSRSSSPLQL
NLLQEEMPAPSESADAVRRGA-GPD

PF12114 // ENSGT00510000046467_0_Domain_1 (1106, 1387)

AKHHCV-------------TGPSGSRSRHRT----
--S------------GELATATAQQECP--------------------------------
-------------------------------------------------------SAAAS
GSSASSIYFRSTDYASEVSENRQRPQDR-QRDKALPGAAEESIWRMIERTPECVLMTYQV
PERGRE--EVLKQDLEKLQSMEQQQPLFSPAQREELAKVRSWIHSHTAPQEGHLQSCVAC
EGRGSVGDT-AEVLEQHPAED--TS---------------------------

MDPCGDPAKPGGDCPHSRGQGL------------------QGAAGQEGPLLGTSVDSSHS
EHEDRNRMSEELLKVVQEMKKSFPAER--HTKPSTLDALNYALRCVLSVQANSGFFPSLG
P-HGAPQTDVTAYSPEELASITSELASKNTFQYLLPQVVTAGFVEQDTFVAVFS-FLSGR
LVHISEQAALILNSKKDTLESSHFVDLLAPQDVSVFYTHTAPTQLPFWNNWTQRAS-QCE
YAP-VKSFFCRICGG-GDRAQKKLCSPFRILPYLVHVQNSAQPE----PEPCCLALAEKI
HSGYE------APRIPVDKRIFTTTHTPGCVF

PF08447 // ENSGT00510000046467_0_Domain_0 (333, 421)

LEVDDRAVPLLGYLPQDLIGTSILTYLH
PEDRPLMFAIHQK-VLKYVGHPPFEHLPIRFCTQNGDYIILDSSWSSFVNPWSRKVSFII

ENSGT00510000046467_0_Linker_0_1 (421, 1107)

GRHKVRTSPLNEDVFATRIKKATNNDKDITELQEQIHRLLLQPVHARA--SSGYGSLGSS
GSQEQHISIASSSESSGHCVE-----EAQKEQVTLQQVYASVNKIKNVGQQLYIESRSR-
SV-KPVMDTRMELQGG-------------DEQKDFSPSQTL---KNKYMCTGSCDDLRRE
QHSSSYQQMNCIDSVIR--YLRSYSLPALKRKCISYTNTSSS-SEEAKQNH-EADCSTAL
Q---------------DTEQILDIHKSETPATGPSTDADGGAA---WTLSTAALSMGSGI
SQCNCSSTAVHAPPLHSE------GAV--------LVCKPW-SPRT----QPSPLTAEEF
RHVGLTAAVLSAHTQKEEQNYVDRFRERILTSPYSCYLQQESRNN---AKCSSV--QGSP
PKQSRCAGKERRKHKRKRLPVPLGTSSS------SANFCSH----IRGLLPDVQPWSPSI
VCSPHAESLAF-PAALVAPSQAPY--VLSSFPFP-DVASLGVGDSAGWGAAVE---CPPL
S-TGPQSVPAFPSAYLDTFTTIFLHNSPIFPLWSA----SFP--------SYPFLGATAS
SGMTPLV-PA------MAP-HLEPTSSDHSQRRVGESWETHGE-EHPF-ISSRSSSPLQL
NLLQEEMPAPSESPDPVRKGI-GPES

PF12114 // ENSGT00510000046467_0_Domain_1 (1107, 1396)

ECHCI-------------TGNSGSRSGPCA----
--T------------GELAAASVHQESQ--------------------------------
-------------------------------------------------------SAAAS
GSSASSMYFSSSDYS-EFSENGQKSQDR-QRDEAFPGVAEESIWRMIEQTPECVLMTYQV
PKRGRE--EVLREDLEKLSSMEQQQPQFSPAQKEELAKVRSWIHSQTAPQGRHLQNCVAC
EDRGSAGNT-AEAHEQHPGED--TS---------------------------

MDPCGDPAVPSGDCPHSGGPGL------------------QGTSDQEGPLQGTCVDSSHS
EHEDRNRISEELIMVVQEMKKYFPAER--RTKPSTLDALNYALRCVHSVQANP----RLS
P-HGVPQADVTAYSLEELASLASEHASNNTVRVHE-------------FL----------
----------IINKYLCFLFHLHL----------------LGHSQPFHTGLSA-------
SGP--ALMTFDLFSGGEDRAQKKHYSPFRILPYLVHVHSSAQPE----PEPCCLALVERI
HSGYE------APRIPVDKRIFTTTHTPGCVF

PF08447 // ENSGT00510000046467_0_Domain_0 (333, 421)

LEVDERAVPLLGYLPQDLIGTSILTYLH
PEDRPLMVAIHQK-VLKYVGHPPFEHSPIRFCTQNGDYVILDSSWSSFVNPWSRKVSFII
GRHRVRTSPLNEDVF---------------------------PVHASA--SSGYGSLGSS
GSQEQHISITSSSEASGHCME-----EAQKEQMTLQQVYASVNKIKNVGQQLYIESMAR-
SV-KPVMDTCMELQGG-------------GKSLTVVIY---------WLCSSVCFNK---
--------------ELA--F----------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------

MDPCGDPAVPGGDCLQTRGAGL------------------QGASGQEGPLQGTCVDSSHS
EHEDRNRMSEDLLMVVQEMKKYFPAER--HTKPTTLDALNYALRCVHSVQANSEFFQSLS
P-HGARQADVTVYSLEDLTSLASEHTSKNT----------------DTFVAVFS-FLSGR
LVHISEQAALVLNSKKGFLKSLHFVDLLAPQDVRVFYAHTAPTQLPFWNNWTQRDS-QYE
CAP-VKPFFCRICGG-GDREQKRHYSPFRILPYLVHVHSSAQPE----PEPCCLTLVEKI
HSGYE------APRIPVDKRIFTTTHTPGCVF

PF08447 // ENSGT00510000046467_0_Domain_0 (333, 421)

LEVDERAVPLLGYLPQDLIGTSILTYLH
PEDRPLMVAIHQK-VLKYAGHPPFEHSPVRFCTQNGDYVILDSSWSSFVNPWSRKVSFII

ENSGT00510000046467_0_Linker_0_1 (421, 1106)

GRHKVRTSPLNEDVFATRIKKAASNDKDIAELQEQIHKLLLQPVHANA--SSGYGSLGSS
GSQEQHISITSSSESSGHCPE-----EGQHEQMTLQQVYASVNKIKNVGQQLYIETMARS
SV-KPVTETCVELQGG-------------DEQKDFSSSQTLKNKS--TTDTGSGGDLRQE
QDSSSYQQMNCIDSVIR--YLTSYSLPALKRKCISCTNTSSS-SEEAKPIP-EADS--SQ
R---------------DTEQLLDIPKQE--TTEPSTDVEGGVA---QTLSTATLSVVSGI
SQCSCSSITDHAPPLQSE------SVA--------VACKPW-ALRT----KASHLSAGRF
KHVGLTAAVLSEHTQKEEQNYVDRFREKILTSPYGCYLQQESRNH---AQCSCAQ-AGST
SQHSRCAGSERRKHKRKKLPAPVDTSSS------GAHLCPH----VRGLLPDEQHWSLSA
SPSPVGAGLAF-P------SQTPY--LLPSFPLQ-DMASQGVGDSGAWGAAAG---CPPL
S-TGPQSVSAFPSAYLDTLMTIFLHNTPLFPLWPP----SFS--------PYPFLGAAGS
SELAP---------------NLEPTTSDHSQRREEENWETHSE-ELPF-FSSRSSSPLQL
NLLQEEMPAPSESADAVRRGA-GPD

PF12114 // ENSGT00510000046467_0_Domain_1 (1106, 1386)

AKHHCV-------------TGPSGNRSRHCA----
--S------------GELATATAQQESP--------------------------------
-------------------------------------------------------SAAAS
ESSTSSINFSSSDYASEGSENSQRPQDR-QRDEALPGTAEESIWRMIARTPECVLMTYQV
PERGRD--EVLKQDLEKLHRMEQQQPLFSPAQREELAKVRSWIHSHTAPQERCLQSCVAC
EDRGSVGDT-TEVLEQHPAED--TS---------------------------

MEPCGDLETPLGEPSGPGGRAV----E-----DEALGEDTGERWSPECHLQRKLADPSHS
EQQDRNRVSEELIMVVQEMKKCFPSER--RNKPSTLDALNYALRCVHSVQANSEFFQILS
Q-NGAPQADVTMYSLEELATIASEHTSKNT----------------DTFVAVFS-FLSGR
LVHISEQAALILNHKKDVLASSHFVDLLAPQDVRVFYAHTARAQLPFWNNWTQRAAPRYE
CAP-VKPFFCRIRGGEDR-EQEKRPSPFRIIPYLIHVHHPAQPESE--SEPCCLTVVEKI
HSGYE------APRIPVNKRIFTTTHTPGCVF

PF08447 // ENSGT00510000046467_0_Domain_0 (333, 421)

LEVDERAVPLLGYLPQDLIGTSILTYLH
PEDRSLMVAIHQK-VLKYAGHPPFEHSPIRFCTQNGDYIILDSSWSSFVNPWTRKVSFVI

ENSGT00510000046467_0_Linker_0_1 (421, 1243)

GRHKVRTSPLNEDVFATKIKKMNNNDKDITELQEQIYKLLLQPVHVSV--SSGYGSLGSS
GSQEQLVSMASSSEASGQCVE-----ETKAEQMTLQQVYASVNKIKIRGQQLYIESRTKS
SV-KPVTGTCTEPNG------------GGDYTACTSFHQTLKNNS---TYTEPHEDWRNE
EHSPSYQQINCIDNVIR--YLKSYNIPALKRKCISCTNTTSSSSEEDKQNH-KVDDVQAL
Q---------------AGLQIPAIPKPEMPTNGWSTDAGGGAP---QILSTTVLSLGSGM
SQCGYSSTTVHVPPPETA-----RDAT--------LMCEPW-TLNM----QPASLTSEEF
QHVGLTAAVLSAHTQKEEQNYVDKFREKILSSPYSSYLQQESRS--K-AKYSYFQG-DSS
SKQTRSAGCRKGKHKRKKLLEPPASSSS------NTGSGP-----RRGAHLNALPCCPSA
ASSPHSSGPTF-PPAAMVPSQAPC--LVPAFPLP-AVTCPGREYAAPGSAPE-VLLGPSA
S-KDLQTCPAFLSPYLATFMTVFLPDPSVCSLLSP----SFF--------PRPFLGVTAS
SAISPSM-SA------MTP-NLDPPPSVTNQRREEEKWEAQSE-GHPF-ISSRSSSPLQL
NLLQEEMPRPSESPDEIRRNR-CPQAEYQCV-------------IGNSGSEGSPAT----
--T------------PTLSTGSPPRETPSHPTAGVLSPGSPPRETPSR---------PTA
SVLSPG--------------------SPPRETPSHP-TAGVL

PF12114 // ENSGT00510000046467_0_Domain_1 (1243, 1387)

SRGSPPRETPSRTGSSAS
GSSDCSIYFTSSAYSSEIPQNGQQSQDV-QKKEIFPSVTEESIWRMIQQTPECILMTYQV
PERVKE--VVLKEDLERLESMKQQQPQFSHGQQEELAKVYNWIQSQAIPQEIDVQACDTC
ESADSADD-VATSSGQAED-----SS--------------------------

MDPCEDLEKSSHKSLDSRETGPPELEGPRACDPEALEKGHEEMWSQKYHLQSPRSESSNS
ERQDRNRVSEELMMVVQEMKKYFPSER--PNKPSTLDALNYALRCVHSVP----------
-------VDVTTYSLEELSTVASEHASKNT----------------DTFVAVFS-FLSGR
LVHVSEQATSILNCKKDFLESSHFVELLAPQDVRVFCAHTVHAQLPFWNSWTQRAS-QYE
FAP-VKSFFCRIRGGEVR-EQEKHYYPFRIIPYLMRVHVSTQRE----PESCCLTLVEKV
RSGYEVFLFFITPRIPMDKRIFTTTHTPGCFLFSCPARLTQ-------------------
---ASL------------------------------------------------------
-MAAARPSPLNEDVFATRIKKTNHNDKDVTELQEQIHKLLLQTHSGCQPL---CLSPGGS
TWQEQRVGGASSGEAGGPRAA-----HAHGEPLTLQQVSASLNKIKNLGQQLYIESMAKS
PD-KQVTAMRTGRLGGESA--------GQHEQKVSSAFLTLKDNS---MHVESSEDWRKD
QYSPSYQQINFIDSVIR--YLRSCDVPALKRKSA------SSSSSEDRQSH-KANDAQTL
H---------------AAPQTPATAHLEMSTARRSADAAGRDP---RSLSPAALSLGSGT
SQCSYGRTVVHAPPPESV--TLAEDAV--------PACEPW-TPCS----HPGLRTSEEF
QHVGLTKAVLSAHAQKEEQNYVDKFREKILSSPYRACLPQESRSK---PKHLYVQG-SSA
YKQSSAAGGKKGKHKGKKLPQLPGSSGT------KDAFCPH----LRGDVQDTQPWGPSL
ASSPWASGLSFPAPS----------------PVP-ALPRGGGGHVAA-VAPFECLSEPRL
P-NCLQSFPAPPPLYLDTLMTIFLHEPPVCPLLSP----SFP--------PYPFLGAPDS
SEIPPSA-SA------VAA-SLEPPWSVLSRRRAEGKWETPRE-ERAL-TTSRSSSPLWL
NLLQEDTLRSRESSDQMRRGI-CPEAEDVNVKNLFLWPSLLQRVVGNSGNKNSY------
-------------------TALL

PF12114 // ENSGT00510000046467_0_Domain_1 (1164, 1385)

HE-----------------------------------
-------------------------------------------------ESPSRTGSAAS
GSSDHSIYSTSGDYSSEITSEGQQSQDV-QKKETFPNFAEESVWRMIKQTPECILMTYQV
PERVKE--TVLKGDLERLVGTRPRQPRFSRAQREELAKVHSWIQSQTVPREIDIQGCVTC
ESKDSLGD-AAESCGQAPAAN--GS---------------------------

----------------------------------------------------------YS
DQLDWSQSHEDLMTMIQEMKKCLPEDKRSSSKPSTISALNYALQCVQQVQANKEFFQALN
D-RRVFQTDVTTYSIEELVTVASEHTPKNS----------------DTFVAVFS-LLSGR
IVHISKQAASILNCKKKVLDSSRFVELLAPEDVSVFYTHTDQSHLPLWNVENQT-DSLFE
YAQ-VKSFFCRLRGGKDQ-EQEKHCYPFRITPYLVHVCTSVHID----AESCCLALAEKI
HSGYE------APRIPMEKRIFTTTHTPGCV

PF08447 // ENSGT00510000046467_0_Domain_0 (332, 429)

FLEIDDRAVPLLGYLPQDLIGTSMLMYLH
PEDRPLMIAVHRK-ILKFAGQSPFEHLPIRFCTQNGDYVILDTSWSSFVNPWSRKVVFII
GRHKVRTSPLNEDVFAARNKEASSVEKEIRELQGQIYKLLLQPVHSSI--SSGYDSLGSS
GSYEHYISISSSSDSNGNCAD------ETQEPITLQQVCADVNRIKNLGQQLYIASWSKP
QNGN-EQAMSSEMLGG----ELIISSFLGRRHSASCFLQRVRSDSTEEPGNILYDDSKRT
PLVPSYQQINCVDSIIR--YLESCSIPVLKRKCKSSTNTSSSSSDDDKKTQQTQQEFKAL
E---------------VNSQTPVSADWEEMLKKQTTAGVVGAPLADLTLS-KSPSVVSAT
SQCSYSSTIVHVPHPQSEVTTMEDAA------VGNEQMELP-PVN------ELIMVPEEL
KPVGLTKETLSAHTQKEEQNYVDKFHQRILLSPFRTYLQQGSRSN---NGHSCGQG-DSP
SLERSTASCKKGKHGKFKCPKPQRQPLDSHSHSKNRNTCSL---PREKRTIQKQSFFPSE
VSCQSSSTMNVFPPVG-FP---VYSDPRSSFPA-----SLVGEELALHSLKPEPTSLSQL
S-CEAPSFPALYPPNLGTFMAVFFHSYPMYSQLPQYA---FLPSPQYIYPPSSYPCATLR
-LAPPPAPSA------VAPNSVNQPFPASSATSTEEQQEGRHHWALQL-SSSRGSSPLQL
DLLQEELPKPVE------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------

--------MPGGKAPDPRRLEA----H-----EEALCGE-SEMWSPKFQLQRKYVESSNS
EQQDRNRVSEELIMVVQEMKKYFPSER--HSKPSTLDALNYALRCVHSVQANSEFFQLLS
Q-NGAPQADVTMYSLEELATIASEHTSKNT----------------DTFVAVFS-FLSGR
LVHISEQATLILNYKKDCLESSHFVDLLAPQDVRVFYTHTARAQLPFWNNWTQRAS-QHN
YAP-VKSFFCRIRGGEGRREQEKYYSPFRIIPYLIHVHSPTHPE----PEPCCLTLAEKI
HSGYE------APRIPVDKRIFTTTHTPGCVF

PF08447 // ENSGT00510000046467_0_Domain_0 (333, 421)

LEVDERAVPLLGYLPQDLIGTSILTYLH
PEDRSLMVAIHQK-VLKYAGHPPFEHSPIRFCTQNGDYIILDSSWSSFVNPWSRKVSFII
GRHKVRT-----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------MSASSSYGSLGGS
GSQEQQVNITSSSESSGHCVE-----EAQKE-----PIYASVNKIKNLGQQLYIESMTRS
SV-KSVMGTCMELQGG-------------DKQKDFASSQTLKNKS---------------
----------------I--YLKSYSIPALKRKCISCTNTASSSSKEDKQTH-KAMTSQHY
V-----------------------------------------------------------
--------------------------A--------LSCKPW-TPKT----QPGALTEEEF
EQVGLTAAVLSAHTQKEEQNYVDRFREKILASPYGCHLQENRNK----AKCSCVQV-DST
SKQSRSAGGKKWKHRH-KTPTPLDASSS------NTAFCPR----VRGSFRMYS------
------------PGAL----------LLPPLPTPQAMTSLG---GGAWGAAPA---RLPV
S-TTTQSLPAHPSPYLDTLMTIFLQNTPIFPLWSP----SFS--------PCPFLEDTGS
SETTLPV-PA------VAP-NLEPPSSVSIQRRVEDRWETERE-EHPW-VSSKKSLSLQL
NQLQEKVPGCSQSPDAVRRNV-CPETECPHV-------------TD-NGNR

PF12114 // ENSGT00510000046467_0_Domain_1 (1132, 1394)

IGHST----
--R------------GELSTASVYKDSP--------------------------------
-------------------------------------------------------SGAGS
GSSNSSIYFTKSEYSSEISESEQRPQDI-QKTEAFPKLVEESIWKMIEQTPECILMTYQL
PARAKE--AVLKEDLEKLESMKLCQPHFSSGQKEELAKAHSWIQSHAVPQEVHPQSCVAC
EDTCSADDT-AESHEVNTSVE-------------------------------

MDPCGDPAVPGGDCPQTRGPGL------------------QGASGQEGPLQGTCVDSSHS
EHEDRNRMSEELIMVVQEMKKYFPAER--HTKPSTLDALNYALRCVHSVQANSEFFQSLS
P-RGAHQADVTVYSLEDLTALASDHTSKNT----------------DTFVAVFS-FLSGR
LVHISEQAALILNSKKGFLKSLHFVDLLAPQDVRVFYAHTAPTQLPFWNNWTQRAS-QYE
CAP-AKPFFCRICGGGGDREQKRLYSPFRILPHLVHVHSAAQPE----PEPCCLTLVEKI
HSGYE------APRIPVDKRIFTTTHTPGCVF

PF08447 // ENSGT00510000046467_0_Domain_0 (333, 421)

LEVDERAVPLLGYLPQDLIGTSILTYLH
PEDRPLMVAIHQK-VLKYAGHPPFEHSPVRFCTQNGDYVILDSSWSSFVNPWSRKVSFII

ENSGT00510000046467_0_Linker_0_1 (421, 1106)

GRHKVRTSPLNEDVFATRIKKAASNDKDIAELQEQIHKLLLQPVHASA--SSGYGSLGSS
GSQEQHVSITSSSESSGHCPE-----EGQHEQMTLQQVYASVNKIKNVGQQLYIESMARS
SV-KPVTETCVEPQGG-------------DEQKDFSSSQTLKNKS--TTDTGSGGDLQQE
QRSSSYQQMNCIDSVIR--YLTSYSLPALKRKCISCTNTSSS-SEEAKPIP-EADS--SQ
R---------------DTEQLLDIRKQE--TTGPSTDIEGGAA---RTLSTAALSVASGI
SQCSCSSTSGHVPPLQSE------SVA--------AACKPW-ALRT----KASHLAAGGF
KHVGLTAAVLSAHTQKEEQSYVDRFREKILTSPYGCYLQQESRNR---AQYPCVQ-AGST
AKHSRCAGSERQKHKRKKLPAPVDTSSS------GAHLCPH----VTGFLPDEQHWSPST
SPSPLGAGLAF-PSALIVPSQTPY--LLPSFPLQ-AMASQGVGDSAAWGAAAG---CPPL
S-AGPQAVSAFPSAYVDTLMTIFLHNAPLFPLWPP----SFS--------PYPSLGAAGS
SELAPLL-PA------MAP-NPEPTTSDHNQRRVEENWEAHSE-ELPF-ISSRSSSPLQL
NLLQEEMPAPSESADAVRRGA-GPD

PF12114 // ENSGT00510000046467_0_Domain_1 (1106, 1386)

AKHHCV-------------TGPSGSRSHHCT----
--S------------GEPATATAQQECP--------------------------------
-------------------------------------------------------SAAAS
GSSASSIYFSSSDYASEVSENRQRPQDR-QRDQALPGAAEESIWRMIERTPECVLMTYQV
PERGRE--EVLKQDLEKLQSMEQQQPLFSPAQREELAKVRSWIHSHTAPQEGHLQSCVAC
EVRGSVGDT-AEVLEQRPAED--TS---------------------------

MDPCGDPAV-GGDCPHNRG--------------------------QEGPLLGTFVDSSHS
EHEDRNRISEELIMIVQEMKKYFPAER--HTKPSTLDALNYAVRCVHSVQANRDFFSNLS
P-HGAPQTDVSAHGLEELAGLTSEHASKNT----------------DTFVAVFS-LVSGR
LVHISEQAASILNSKKDFLTSSRFVDLLAPQDVRVFYTHTIQSQLPFWSNRTQRAS-QYG
YAS-VKSFFCRICGG-GDRAQKKHYSPFWILPYLVHVHSSAQPE----PEPCCLALAEKI
HSGYE------APRIPVNKRIFTTTHTPGCVF

PF08447 // ENSGT00510000046467_0_Domain_0 (333, 421)

LEVDERAVPLLGYLPQDLIGTSILTYVH
PEDRPLMVAIHQK-VLKYVGHPPFEHLPIRFCTQNGDYVILDTSWSSFVNPWSRKVSFII
GRHKVRTSPLNEDVFATKIKKAPNNDKDIADLQEQIHRLLLQPIHASA--SSGYGSLGSS
GSQEQHVSIPSSSESSGHCVE-----EAQKEQMTLQQVYTCVNKIKNVGQQLYLESMAR-
SV-KPVMDMCVELQGG-------------AACMHSEVQ--LLSS----------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------

------------------------------------------MWSQKFQLQSLQVESSNS
EQQDRNRVSEELVMLVQEMKKYFPSGR--HSKPSTVDALNYALRCVHRVQANSGFSQTLS
Q-SGAPQAAATTYSLEELGMATSGYPSKNT----------------DTFVAVFS-FLSGR
LVHISEQAASILNCKNDFLESSHFVELLAPQDVRVFCAHTAHARLPLWNSWAQTAS-QYD
STP-VKSFFCRIRGGQDT-EQEKHYCPVRIIPYLLHVCSSAQLE----SEPCCLILVEKI
HSGYE------APRIPVDKRIFTTTHTPGCVF

PF00989 // ENSGT00510000046467_0_Domain_0 (333, 420)

LEIDERAVPLLGYLPQDLMGTSVLAYLH
PEDHSLMLTVHQK-VLKYAGHPPFEYLPIRFCTQNGDYVILDSSWSSFVNPWSRKVSFI

ENSGT00510000046467_0_Linker_0_1 (420, 1104)

I
GRHKVRTSPLNEDVFATRKRKTNSHDKDITELQEQIHKLLLQPVHRGA--SSGFGSLGGS
GSHAPCVRLAASRKSSGPRAE-----AAPGTELPPQQVCASGNKTTTLGQQLYVESTAKP
PG-LKSKGDTC------------ISIEVSDEQKASSTFQTLKNNS---MPLESYEDWRKD
QHNPSHQQINCIDSVIR--YLKSYNIPALKRKCISCTNTTSSSSEKDRHNH-KPNDAEDL
H---------------------AIANLEMPTTGRPALAAGGTP---RTLAPTALSLGSGL
NQCSYRSTLIPAPPPETG------AAF--------TFCSQW-QIRK----NNEHTKEGQK
RRKRATAMTTRGRMSNEVHSYIRKWTDRVDEVLYACCCNNSCKNLLKYASLSMVAG-DSA
SKQAGSAGCKKGKPGRKKPSGPWNSRDA------QDTFCPR----LGGDGRHRQPWSPSL
ASSLPS------PAALMAPDLATY--LVPALP------SVGRDHAVSLTALN-RLPKATL
W-NDLQTFPALPS-SLDTVMTIFLPDPHGCPLLSP----SFC--------PYDFLGTAGS
SGTLASL-SA------VAP-HLEPLSSVPGRRRAEGKWEMRCG-EHPC-VNSGSSSPLQL
NLLQADMLGSCESSDQTRRDI-C

PF12114 // ENSGT00510000046467_0_Domain_1 (1104, 1386)

PEAKSNRI-------------SGSRGK-SSGFA----
--T------------GELSTALLHEEP---------------------------------
---------------------------------------------------PSGTGSAAS
GSRDSSVDFASTDC-PETTSNGQQSEDA-QEEETFPGLADEAMWRRRKQTPERVLMTYQV
PERVTE--AVLSEDLEKLAGLQGRQPRFLCGQREELAKVHSWIQSQTVPQGIDIQGCVTC
ESQDSPGD-TAEPCGQAPA-----ANSG------------------------

------------------------------------------------------------
EQQDRNKTSEELMMVVREMKRHFPSER--SHKPSTLEALNYALRCVHSVQXXXXXXXXXX
X-XXXXXXXXXXXXXXXXXXXXXXXXXXXX----------------DTFVAVFS-FLSGK
LVHVSEQATLILNCKKNSLASSPFVELLAPQDVRVFYANTAQAHLPFWNVSTQTXX-XXX
XXXXXXXXXXXXXGGKDR-EQEAHYYPFRITPYVINVYSSADAE----AEPCCLTVVEKI
HSGYE------APRIPVNKRIFTTTHTPGCV

PF08447 // ENSGT00510000046467_0_Domain_0 (332, 429)

FLEVDERAVPLLGYLPQDLIGTSVLMYLH
PDDRPLMFAVHQK-ILKYAGQTPFEHSPVRFCTQNGDYVILDSSWSSFVNPWSRKVSFII
GRHKVRTXXXXXXXXXXXXXKMSSIDKDIIELQDQIYKLLLQPVHVSG--SSGYGSLGSN
GSQEHYVSIASSSESSGNCVE-----EIQKEPMTLQQVCATVNRIKNLGQQLYIESRTKL
SN-QQFVGSGTEQQGG-E----------LNKKSSHPSFQELRNSS---LGTDSCDDLRKD
QHTPSYQQINCVDSIIX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
X-------------------X-XXXX-XXXX------------XXXXXX---XXXXXXXX
XXXXXXXXXXXXXXXXXXX-XXXXXXX-----XXXXXXXXX-SLSL----QTLPVAPEGF
RQVGLTKAVLSAHTQKEEKNYVDRFREKILSSPYCSYLQPDGRSK---MRYPLIPG-DTP
SKQAPSAGCKKGKHKRLKLPVSSHSSGS------TICL--L----CWKHHPGRPPWLPSD
MTSWL---------MWGCTLLAPS--PATGFPVLPPMSPVRAQCTASVPGLG-PHPELSP
A-YRMQPLPTFPSPYVGAFMTIILHNTPACPQMCQ----PFS-------SPCPFWGVPGC
SEIVPAPLPSSSPVQPQED-LPELPSPASSQRSAEEEWVLQSDQEHPLFSHSRSSSPLQL
NLLQEEMPGAPEP-LPPMRQEADTGV--------------------------QNSM----
--A------------KGLFTLLLHKDSP--------------------------------
-------------TGADSAA---------------------------------------S
GSSDSSRYFASSDSSSEISQNGQKSE----KKEAPHKSGRDAIWGMIEQTPKCILMTYQV
PERVKE--DVLKEDLEKLESMKQHQPQFTEGQKEELAEVHPWIQSHTVPREIDTHGCVTC
DSKRSLGVGALP-YEKSLEEHSW-----------------------------

--------TPRGEPPGPGGRGT----E-----DEALGEESGERWSPEFHLQRKLAESSHS
EQQDRNRVSEELIMVVQEMKKYFPSER--RNKPSTLDALNYALRCVHSVQANGEFFQILS
Q-NGAPQADVTMYSLEELATIASEHTSKNT----------------DTFVAVFS-FLSGR
LVHVSEQAALILNRKKDVLASSHFVDLLAPQDVRVFYAHTARAQLPFWNNWTQRAAPRYE
CAP-VKPFFCRIRGGEDR-KQEKRHSPFRIIPYLIYVHRPGQPESE--SEPCCLTVVEKI
HSGYE------APRIPVNKRIFTTTHTPGCVF

PF08447 // ENSGT00510000046467_0_Domain_0 (333, 421)

LEVDERAVPLLGYLPQDLIGTSILSYLH
PEDRSLMVAIHQK-VLKYAGHPPFEHSPIRFCTQNGDYIILDSSWSSFVNPWSRKVSFII

ENSGT00510000046467_0_Linker_0_1 (421, 1180)

GRHKVRTSPLNEDVFATKIKKTNNNDKDVTELQEQIYKLLLQPVHVSV--SSGYGSLGSS
GSQEQLVSIASSSEASGHCVE-----ETKAEQMTLQQVYASVNKIKNLGQQLYIKSMTKS
SF-KPVTGTRTELNGGGESAN-----DGGEYKTFTSFHQTLKNNS---VYTEPYEDLRND
EHSPSYQQINCIDSVIR--YLKSYNIPALKRKCISCTNTTSSSSEEDKQNH-KADDIQAL
Q---------------AGLQISTIPKSEMPTNGPSIDAGGGAP---QILSTAVLSLGSGI
SQCGYSSTIVHVP-PETA-----RDAT--------LVCEPW-TLNM----QPAPLTSEEF
KHVGLTAAVLSAHTQKEEQNYVDKFREKILSSPYSSYLQQESRS--K-AKYSYFQG-DYT
SKQTQLAGCRKGKHKRKKLPEPPDTSSS------NAGSGP-----HRGVRQNAQPCCPST
ASSPHTLGPTF-PPAAMVPSQAPY--LVPAFPLP-AATCPGREYAAPGTVPE-GLHGPPL
S-KDLQPYPAFPSPYLDTFMTVFLPDPPVCPLLSP----SFF--------PCPFLGATAS
SAISPSMS-A------MTP-TLDPPASVTNQRREEEKWEAQSE-GHPF-ITSRSSSPLQL
NLLQEEMPRRSESPDQMRRNT-CPQAEYQCV-------------AGNSSSESSPAT----
--T------------GALSMGSPPRENPSHPTAGTLSMG

PF12114 // ENSGT00510000046467_0_Domain_1 (1180, 1388)

SPPSGTPSY---------PTA
SVLSTGSPPCESLSGTGSA---------------------------------------AS
GSSDSSIYFTSSVYS-KISQNGQQSQDV-QKQETFPNVAEESIWRMIRQTPECVLMTYQV
PERVKE--VVLKEDLEKLENMRQQQPQFSHGQKEELAKVYNWIQSQTVPQEINIQACVTC
ENEDSADG-AATSCGQALA-----ES--------------------------

--------MSSGKSHGSRGRRT----R-----GETLGKDPEELWRQKYQPQSKYLESSNS
EQQDRNRVSEELITVVQEMKKYFPSEK--HNKPSTLDALNYALRCVHSVQANSEFFQILS
Q-NGAPPADVTAYSLEELASIASEHTSKNT----------------DTFVAVFS-FLSGR
LVHISEQATSILNCKKDFLESSHFVELLAPQDVRVFCTHTAHAQLPFWDNWIRRAASQRE
YPP-EKPFFCRIRGGEDR-KQEKHCYPFRIIPYLDHVQNSAGRE----PEPCCLTLAEKI
HSGYE------APRIPVDKRIFTTTHTPGCV

PF08447 // ENSGT00510000046467_0_Domain_0 (332, 429)

FLEIDERAVPLLGYLPQDLVGMSVLTYLH
PEDRPLMVAIHQK-VLKYAGRPPFEHSPVRFCTQNGDYIRLDSSWSSFVNPWSRKVSFII
GRHKVRTSPLNEDVFANRIKKTNNIDKDITELQEQIHKLLLQPVPMSA--SSGYGSLGSS
GSQEQQVSVASSSESSGHCAE-----DARKEPLTLQQVYASVNKIKNLGQQLYIESMTRS
PS-QQATGVHGP---------------AGKQK-AFSSFQTLKNNS---TYTESYEDLRKE
QHSPSYQQINCIDSVIR--YLRSYSIPALKRKCISWTNTTSSS-EEDRHNH-KAGAGQAS
QA--------------ADPQIPAAPTSEPPPNGPAPDAKGRAA---RTPSTAAPSLGSGV
SQCSYSSTIVHAPPPESA-----RDTT--------PACEAW-PPSA----HPAPLTPDEF
RHVGLTKAVLSAHTQKEEQNYVDKFREKILSPPYSSYLQQEGRG--K-AKYSYVQG-ESS
SKQSRPAAGRKGKHKRKKLL-PTDSCSA------RDACCPH----LTARVQDAQPWWPAA
TP---APGLSF-PAAVLVPSPAPC--LVPAVPAL-PAVXXXXXXXXXXXXXXXXXXXXXX
X-XXXXXXXXXXXXXXXXFVTVFLPDPPIWPLAPS---------------CTPFLGAADS
S-ITPCLVSA------AAA-NQEPPFSVIDRSRPRGPEETRSE-GCLS-VPSGTSSPLQL
SFLGEVAPGARE-------PA-GPHTQCQCV-------------TGNGGKKNCGFT----
--A------------SDLSAASLHKEAPC-------------------------------
-----------------------------------------------------RLDSAAA
GSSDSSVYFTSSDDSPDIPPNGQPSRDA-LETAAFP-VAEESIWTMIKQTPECILMTYQV
PERVKE--IVLREDLGKLDSMRQQQPQFSPGQRAELAAEHPWLQSQTIPPEIDTQGCVTC
KQEDSTGE-AADLYGQVPA-----GDSS------------------------

-------------------RAA----E-----DEALGEDSGEWWSPEFHLQRKLADPSHS
EQQDRSRVLEELTMIVQEMKKYFPSER--RNKPSTLDALNYALHCVHSVQANSEFFQILS
Q-NGAPQADVTMYSLEELATIASEHTSKNT----------------DTFVAVFS-FLSGR
LVHISEQAALILNRKKDVLASSHFVDLLAPQDVRVFYAYTARAQLPFWNNWTQRAAPRYE
CAP-VKPFFCRIRGGEDR-EQEKRPSPFRIIPYLIHVHHPAQPESE--SEPCCLTVVEKI
HSGYE------APRIPVNKRIFTTTHTPGCVF

PF08447 // ENSGT00510000046467_0_Domain_0 (333, 421)

LEVDEKAVPLLGYLPQDLIGTSILTYLH
PEDRSLMVAIHQK-VLKYAGHPPFEHSPIRFCTQNGDYIILDSSWSSFVNPWTRKVSFII

ENSGT00510000046467_0_Linker_0_1 (421, 1234)

GRHKVRTSPLNEDVFATKIKKMNNNDKDITELQEQIYKLLLQPVHVSV--SSGYGSLGSS
GSQEQLVSMASSSESSGHCAE-----ETKAEQMTLQQVYASVNKIKNRGQQLYIESRTKS
SV-KPVTGMCAELNGGGESENLLNPGGGGEYKACTSFHQILKNNS---MYAEPHEDLRND
EHSPSYQQINCIDSVIR--YLKSYNIPALKRKCISCTNTTSSSSEEDKQNH-KADDVQAL
Q---------------AGLQIPVIPKPEMPANGRSTDTGGGAP---QILSTTVLSLGSGM
SQCGYSSTIVHIPPAETA-----RDAT--------LMCEPR-TLNM----RPAPLTSEEF
KHVGLTAAVLSAHTQKEEQNYVDKFREKILSSPYSSYLQQESRS--K-AKYSYFQG-DST
FKQTWSACCRKRKHKRKKMLEPPGSSSS------NAGSGH-----RRGAHLNAQPCCPSV
ASSPHSSGPTF-PLAAMVPSQAPY--LVPAFPLP-AVTCPGREYAVPGTAPE-VLPGPSS
S-KDQQTCLGFPSPCLDTFMTVFLPDPSVCPLLSP----SFF--------PCPFLGETAS
SAILPSM-SA------MTP-NLDPPPSVTNQRREEEKWEAQRK-GHPF-ISSRSSSPLQL
NLLQEEMPRPSESPDEM-----CPQAEY-CV-------------IDNSGSEGSPAA----
--T------------PALFTGSSPRETPSHPTAGVLSPGSPPRETPSH---------PTA
SVLSTG--------------------SPPRETT

PF12114 // ENSGT00510000046467_0_Domain_1 (1234, 1392)

SHP-TASILSPESPPRETPSRTGSAAS
GSSDCSIYFTGSAYSSEISQNGQQSQDI-QKKEIFPNVAEESIWRMIQQTPECILMTYQV
PERVKE--VVLREDLERLESMKQQQPQFSHGQQEELAKVYNWIQSQAIPQEIDVQACVTC
ESADSGDD-AATSSGQAED-----SS--------------------------

-----------------------------------------------------------S
DQMDRTRSHKELMSMVQEMKRRLPHEKFNRNKPSTVDALNYALKCVRQVQANSAFFQVLS
D-SGTCRMDSAVHTIEDLETITSEHPPKNT----------------DTFVIVFS-LTSGK
MVYISEQAAYILNCKKKLLDSSRFVELLAPQDVSVFYKHTTQSHLLPWNIGAETAS-LYE
YTQ-VKSFFCRIRGGKDR-EHEIRYNPYRMTPYSVKVRSSDNAE----PEPCCLALV

PF00989 // ENSGT00510000046467_0_Domain_0 (298, 426)

EKI
HSGYE------APRIPLDKRIFTTTHTPGCVFLEVDDRAAPLLGYLPQDLVGTSVLMYLH
PEDRPLMLAMHKKVVLKYAGQPPFEHSPIRFCTQNGDYITLDTSWSSFVNPWSRKVAFII
GRHKVRTGPLNEDVFSAPSREILSTDKEIKELQGQIYKVLLQPVHNNG--SSGYGSLGSN
GSYEHYISIASSSDSNGNCVD-----ETQKEPMTLKQVCTDINRIKNIGQQVYIDTRSHS
TG-KPNTNTFVKPQL---------------------------ENTMEGQTTSTCDTSRKG
QHIPSYQQINCVDSIIR--YLESYNIPALKRKCESSTNTTSSSSEDDRVPI-DTSQLSAE
S--------------------------MVTTDAQTTAAVVGAPLTDLTLSIKAMSVVSVT
SQCSYSSTIVHVPQPESEL----------------LVCEVW-YEEVTAIEDAAGGTPEEF
KQIGLTKEVLSAHTQKEEQEYVDRFRQRILQSPYSSYLQQDSRS----KGCSHEQGM--L
EK----KYCFPHNRKKKQLK-DVSTRAP------GSHSAP-----IILENPNRHQWPPSI
IVNILLNRLLL----LLLKRERNKVNTSVRNPLP-PVTG---NNAASAIASESSPQQSNM
S-YNLPAFPGFASPYMGTFMAVLLPNYNMYPQMNPQIPPPFFPTQFPLSSSYPYAGMSSA
PQSMPSQ---------VPT-DFVDPTSRASSPMSADGLEVQSEDPQMF-SNSRSSSPLQL
VLLQEELPKAMEQAEGTNEES-QVDI--KCV-------------SYIFGNSAISCL----
--R------------GRKACPYSQQS----------------------------------
---------------------------------FKA------------------ATHSWS
LENASFLLWSNRFYI----------MELQKRSLLLPVRTGIFLWV------KNLLFVSGL
LCRDKE--TLLKEDLEKLTAMRNKQPWFTEEQKEELAEVHSWIRNRTIPQEIDTQGCVMC
LKSSTKDEKHVQRKDGDPKED--AA---------------------------

MEPRGDLETPRGEPPGPGGRGA----E-----DEALGEESGERWSPEFHLQRKLAESSHS
EQQDRNRVSEELIMVVQEMKKYFPSER--RNKPSTLDALNYALRCVHSVQANGEFFQILS
Q-NGAPQADVTMYSLEELATIASEHTSKNT----------------DTFVAVFS-FLSGR
LVHVSEQAALILNRKKDVLASSHFVDLLAPQDVRVFYAHTARAQLPFWNNWTQRAAPRYE
CAP-VKPFFCRIRGGEDR-KQEKRHSPFRIIPYLIYVHRPGQPESE--SEPCCLTVVEKI
HSGYE------APRIPVNKRIFTTTHTPGCVF

PF08447 // ENSGT00510000046467_0_Domain_0 (333, 421)

LEVDERAVPLLGYLPQDLIGTSILSYLH
PEDRSLMVAIHQK-VLKYAGHPPFEHSPIRFCTQNGDYIILDSSWSSFVNPWSRKVSFII

ENSGT00510000046467_0_Linker_0_1 (421, 1179)

GRHKVRTSPLNEDVFATKIKKTNNNDKDVTELQEQIYKLLLQPVHVSV--SSGYGSLGSS
GSQEQLVSITSSSEASGHCVE-----ETKAEQMTLQQVYASVNKIKNLGQQLYIESMTKS
SF-KPVTGTRTELNGGGESAN-----DGGECKTFTSFHQTLKNNS---VYTEPYEDLRND
EHSPSYQQINCIDSVIR--YLKSYNIPALKRKCISCTNTTSSSSEEDKQNH-KADDVEAL
Q---------------AGLQISTIPKSEMPTNGPSIDAGGGAP---QILSTAVLSLGSGI
SQCGYSSTIVHVP-PETA-----RDAT--------LLCEPW-TLNM----QPAPLTSEEF
KHVGLTAAVLSAHTQKEEQNYVDKFREKILSSPYSSYLQQESRS--K-AKYSYFQG-DYT
SKQTQLAGCRKGKHKRKKLPEPLDSNSS------NAGSGP-----HRGARQNAQPCCPST
ASSLHTLGPTF-PPAAMVPSQAPY--LVPAFPLP-AATCPGREYAVPGTVPE-GLHGPPL
S-KDLQPYPAFPSPYLDTFMTVFLPDPPVCPLLSP----SFF--------PSPFLGATAS
SAISPSMSSA------MTP-TLDPPASVTNQRREEEKWEAQSE-GHPF-ITSRSSSPLQL
NLLQEEMPRRSESPDQMRRNT-CPQAEYQCV-------------AGNSSSESSPAT----
--T------------DALSMGSPPRENPSHPTASTLSM

PF12114 // ENSGT00510000046467_0_Domain_1 (1179, 1388)

GSPPSGTPSH---------PTA
SVLSTGSPPCESLSGTGSA---------------------------------------AS
GSSDSSIYFTSSVYS-KISQNGQQSQDV-QKKETFPNVAEESIWRMIRQTPECVLMTYQV
PERVKE--VVLKEDLEKLESMRQQQPQFSHGQKEELATVYNWIQSQTVPQEINIQACVTC
ENEDSADG-AATSCGQALA-----EDSS------------------------

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----------------MVPSQAPC--PVPAFPLP-AMASLESEYTALVAALE-RPPAPPL
P-SSLQSLPAFPSPYVNPFVTIFLHEAPPYPLL------SFS--------PCPFLGATGS
SEMPPSV-SS------ETP-NLEPPSSVSP-QGVEEKWEAQSE-EHPC-TE

PF12114 // ENSGT00510000046467_0_Domain_1 (1072, 1386)

SSCSSPLQL
NLLQEEMPRSSESSDQLKRDI-CPETEYQYI-------------TGNGGNKGNHST----
--A------------SELSSVLLHKDS---------------------------------
---------------------------------------------------PFRTGSAAS
GSSDSSIYSTSSDSSSEISQNEQKSQDV-QEKEPFPNLAEESIWRMVEQTPERILMTYQV
PERVKE--VVLKEDLEKLKSMRRQQPHFSLGQKKELAQVHSWIQSQTIPQEIDIQGCVTC
KNKGSVGG-SAQSCEQGPAVD--SS---------------------------