Query Results 

------------------------------------------------------------
-----------------------------------------------------W--GSQA
RPG-----SRNC-I--LGFC----------------------------------------
----F--PG

PF07686 // ENSGT00470000042273_0_Domain_0 (190, 350)

CF---S-----------LQGPE-SVRG------LVGGSVTMQCYYTPGWKA
Y-EKWWCRG---AE--W----NSCQ-ILVQT-NGSEQ--EVKGDRVSIRDNQRHGLLTVT
MEEVRRDDTDTYWCGISRNGP-------------DLGA-S--VKV--TIDPGTWPTQSSS
GHSTVP------------------------------------------------------
------------------------------------------------------------
--------LLS-GPP-----------ASLPSAFGGCRRMSKELEGPQ-----------KG
LELT--VDHYILLAFLKV-----PVLLV------LVGAVL-CLKGS---------QQRPS
I--------------S------MNLPSDL--HR---------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
-----------------------------------------------------------M
SRRGRVPWLSWA-------LLLLW------------------------------------
----V--PGCWS---L-----------

PF07686 // ENSGT00470000042273_0_Domain_0 (208, 343)

RGPR-SVTG------TVGGSVSVQCQYEEKFTE
N-DKYWCKN---LC--------VWK--MVKT-EGANR--EVRSGRVSIRDHPANLTFTVT
LERLTEDDAGTYRCGIDSSGLPGY--------LFDHTS-Q--VVL--SVTPGVG-SSAQK
ARCT--------------------------------------------------------
---------KERGSTLVP-ALRIQR--AAL---WEGG-----------------------
---------------------SRVERQAPAQQLAL-------------------------
SKLQ---------VLLSL-LALLLLLLG------GSSLLA-WRMVRR--RLKS--GENPK
QLRS---------PSQ-----VRQQG-----EPHYA------NLELQT-----WP-----
---LREE--PMHPRQPE-VEYSTVK----------------------AP------REEPY
YSTVVFD--FQSGGSEANSIRS------QRTRD----EET--QYSVIKKT----------
----------------------

------------------------------------------------------------
-----------------------------------------------------------M
TWQGRVAWLPWA-------LLLVW------------------------------------
----G--PG

PF07686 // ENSGT00470000042273_0_Domain_0 (190, 348)

SWS---L-----------SGPN-SMTG------TVGRSLSVQCRYEEKYRE
N-AKYWCKN---RC--------VWK--IVET-KAADR--EVRKNRVSIRDHRANLTFTVT
LESLTKGDAGTYWCGIDTSWLSGH--------FRDPTL-R--VVV--SVSPGEL-CTPPP
PAPA--------------------------------------------------------
---------PG-L--------------LQG---SQSSSTAPTT---------------M-
-------GAT---H-----SASSQEEFPPSQ---G-------------------------
LGLQ---------ILLSL-LALLLLLLG------GSSLLA-WRMVRR--RVKS--GKNPE
PLRT---------PSQ-----ATQQG-----EPHYA------NLELQM-----WP-----
---LRGE--PVHPRQAE-VEYSTVK----------------------AP------GEEPH
YSSVVFD--FQNEGSKASRIRS------QRTLE----EET--QYSVIKKTHSPGLLDDFI
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MWLPWA-------LLLLW------------------------------------
----V--PGCFA---L-----------SH

PF07686 // ENSGT00470000042273_0_Domain_0 (210, 318)

PR-TVAG------PLGGSLSVQCHYKKEHRS
L-NKYWCRP---PQI-----FL-CD-KIVET-EGSAG--K-RNGRVSIRDSPANLSFTVT
LENLTEEDAGTYWCGVD

ENSGT00470000042273_0_Linker_0_1 (318, 554)

TPWLRDF---------HDPIV-K--VEV--SVFPAST-SMTPA
SITA--------------------------------------------------------
---------A-KTSTITT-A---------F---PPVSSTTLFS---------------V-
-------GAT---H-----SASIQEENEEVVN----------------------------
SQLP---------

PF15330 // ENSGT00470000042273_0_Domain_1 (554, 730)

LLLSL-LALLLLLLV------GASLLA-WRMFQK--RIKA--GDHSE
LSQN---------PKQ-----AAKQS-----ELHYA------NLELLM-----WP-----
---LQEK--PAPPREVE-VEYSTVA----------------------SP------REELH
YASVVFD--S-----NTNRIAA------QRPRE----EEPDSDYSVIRKT----------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MRLLFL----------LWGCLVL-------------------------------
-------PG

PF07686 // ENSGT00470000042273_0_Domain_0 (190, 348)

YG--------------TLVGPK-EISG------FAGESVTLQCTYGDELKK
Y-PKYWCKD---VGVFV----SRCS-TTVYA-GEDGR--ESSKDRVSILDSRRDRTLTVT
LRELTPTDTGKYLCGISKLGF-------------DKTF-Q--VSL--HVFSG--------
--PCCTPSPIPSLQPL----ATRSLQPKAKTWQTQPPE--LTSPALRLPTVTAKQGKMGA
EASPSTGTTLHG---------------------------HSH-----EGTSLYAGT-SP-
-----H-TATS-PPA----GAY-----RL-ATQLS--STSRED---TSLV-PSSSSSRPR
VSIPLVRILAPVLVLLTLLL----F--T------GLAVIGRCMFQW-KK--EAQLAEDT-
-LEK----------EKVHLS---HVNS---------------------------------
--------------------------------------------------------EEDE
--ASLQG-------LERSVILG----PPLHMSGE---ALDFSQSVLP-------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
-----MP-LLML-Y--PLLF---W------------------------------------
----L--SGY---------SI--ATDISG

PF07686 // ENSGT00470000042273_0_Domain_0 (210, 349)

PM-TVNG------LERGSLIVQCVYNSGWET
Y-LKWWCRG---AI--W----KGCK-ILVKT-TGSEQ--EVKRDRVSIKDNQKNHTFTVT
MEGLMQTDADTYWCGIERTGT-------------DLGV-T--VQV--T

ENSGT00470000042273_0_Linker_0_1 (349, 542)

VDPAST----AA
PT--------------TST-------------------------------S---------
---------------TT----------------FTAPVIPEETS-----------N-SP-
-------TLTG-HHL---------DK---------------------------RHNLLKL
S

PF15330 // ENSGT00470000042273_0_Domain_1 (542, 732)

VLL--PLIFTILLLLLV-----AA-----------SLLA-WRIMKCQQ--KA--AGMS-
-------------SEQ------VPQPLEG--DLCYA------DLTLQLTR--TSP-----
QKATTKLSFSAQADQVE-VEYVTMAP---------------------FP------KEDIS
YASLTLAA-EDQEPTYCNMGPL-SSHIPSVGPE----DPT--EYSIIRRP----------
----------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------LCF-----------------------------------
-------PG

PF07686 // ENSGT00470000042273_0_Domain_0 (190, 344)

SLS---L-----------MGPS-SVTG------TLGGSLRVRCQYEELYQR
H-KKYWCRG---PYD------ATCE-KIVET-NGEEK--EERSGRVSIRDHADKLTFIVT
MENLTADDAGPYWCRIQTTWFLDVW-------SRDPSL-P--VNV--SVSAVPVVLGRAY
DEGR--------------------------------------------------------
--------------LP-----------CTM---SRPTSQNPHP---------------W-
----------------------------------T--HLKIRE----EPVISCPYVHPHR
SLLS--SVHFLLLVFLKL-----PLFLT------LVGAVL-WVNRPLRG--SG--GRVLF
PCLE---------GE---------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------Y--------SIA---TEITGPT-MVNG------L-----E----RGSQWET
N

PF07686 // ENSGT00470000042273_0_Domain_0 (242, 348)

-LTWWCRG---AI--W----SSCE-ILVKT-TRSEQ--EVKGDWLSIRDDQKNHTFTVT
MKDLRRDDADTYWCGIERTGT-------------DLGV-K--VQV--TIDPTQ-NSAPEW
TTTTASLAPT----AA--------------------------------------------
------------------------------------------------------------
-------------------------------------------------ATPKTATPLTR
SLFS--STHFLVLVLLEV-----PLLLS------MLGAIL-WVNRLQRR--S--------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MPLLML-F--SLFF---W------------------------------------
----I--SGC---------PI--ATEIT

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 348)

GPT-TVNG------LERGSLTVRCAYGSQWET
Y-LKWWCRG---AI--W----SNCE-ILVKT-TGSEQ--EVKGDRLSIRDDQKKHTFTVT
MKDLRRDDADTYWCGIERTGT-------------DLGV-K--VQV--

ENSGT00470000042273_0_Linker_0_1 (348, 542)

TIDPAST----AT
PT--------------TPT-------------------------------F---------
---------------TT----------------FTALVTLEETS-----------S-SP-
-------TLNS-YHL---------DN---------------------------RYKLLKL
R

PF15330 // ENSGT00470000042273_0_Domain_1 (542, 732)

VLL--PLVFSILLLLLV-----AA-----------SLLV-WRTMKRQK--KA--AGMS-
-------------SEQ------VLQSPES--DLCYA------NLTLQQTR--ASP-----
KKATTKPSSSVQADQVD-VEYVTMAP---------------------VL------REDIS
YASLTLAA-EDQEPTYCNTGQL-TSPIPSGGPE----ESL--EYSTIRRP----------
----------------------

------------------------------------------------------------
-----------------------------------------------------------M
TARAWASWWPSA-------LLLLLV-----------------------------------
-------PGCFA---L-----------S

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 332)

GPR-TVAG------PLGGSLSVQCGYEEEHRT
L-NKYWCRV---RWT-----I-GCA-KIVET-KGSAG--KLRNGRVSIRDRPANLSFTVT
LENLTEDDAGAYWCGVDTPLLHN--------F-HDRFI-Q--VEV--SVFPALTT-----
----------------------------------------------------TAS-----
---------SPQSSTGTW-G---------P---PT--KLPVHT---------------W-
-------P-----------------------SP-------------TREDSPD-PSPRPG
SLLS--SPHFLLLVFLEL-----PLLLS------MLGAVL-WVNRPQRS--SR--S----
-----------------------RWS-----RPDGE------NQ----------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
----------------MSKTLRGNLDKQNESAEISR--ALGIPLRFGFAAGCS-SRSAAK
WEGRT-MWLSPA-L--LLLS----------------------------------------
----F--PGCL--------------SI

PF07686 // ENSGT00470000042273_0_Domain_0 (208, 348)

QGPA-LVRG------PEQGSVTVQCRYSSRWQT
N-KKWWCRG---AS--W----STCR-VLIRS-TGSEK--ETKSGRLSIRDNQKNHSFQVT
MEMLRQNDTDTYWCGIEKFGT-------------DRGT-R--VKV--NVYSVGKDTMSTS
NQ-LPW------------------------------------------------------
----------------------------------------------------------P-
-------TV------------------------------------------DGSTDMVSS
DLQK--RTYYMLLVFVKV-----PALLI------LVGAVL-WLKRSTQK--VP--EEQW-
-----------------------RHTLCS--DLDSEL--LAKDISP--------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
-----------------------------------------------------------M
TQLASAVWLPTLLL----LLLLFW------------------------------------
----L--PGCVP---L-----------H

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 320)

GPS-TMSG------SVGESLSVSCRYEEKFKT
K-DKYWCRV---S-L-----KILCK-DIVKT-SSS-E--EARSGRVTIRDHPDNLTFTVT
YESLTLEDADTYMCAVDIS

ENSGT00470000042273_0_Linker_0_1 (320, 555)

LFDG-------SLGFDKYF-K--IEL--SVVPSED----PV
SS----------------------------------------------------------
---------P-----GPT-L---------E---TPVVSTSLPT---------------K-
-------GPA---L-----GSNTEGHREHDYSQ-G-------------------------
LRLP---------A

PF15330 // ENSGT00470000042273_0_Domain_1 (555, 732)

LLSV-LALLLFLLV------GTSLLA-WRMFQK-RLVKA--DRHPE
LSQN---------LRQ-----ASEQN-----ECQYV------NLQLHT-----WS-----
---LREE--PVLPSQVEVVEYSTLAL---------------------PQ-------EELH
YSSVAFN--SQRQDSHANGDSL------HQPQD----QKA--EYSEIQKPRKGLSDLYL-
----------------------

MVADRKVFLKSLLMITVTCFIARCLEISPVLR--------PSAFC---------------
-------------LFTGGKWPKEEVQEREKAEGLED---------AGAESELTG--STEG
GPGKDKMHGFLF-F--LFLF---Q------------------------------------
----L--AGS--------------SDISG

PF07686 // ENSGT00470000042273_0_Domain_0 (210, 350)

PE-AVRG------LVGGSLTVQCHYVRTWKN
S-KKWWCRG---AN--W----GNCH-ILVKT-NGSEQ--EVQRKNVSIKDNQKNLIFTVT
MEKLKQTDANIYWCGIERYGI-------------DLGV-Q--VKV--TV

ENSGT00470000042273_0_Linker_0_1 (350, 542)

HPAPTTVST--
------------------T-------------------------------S---------
---------------SN----------------AHVSTTPAETK-----------G-PP-
-------TMTS-HHY---------DG---------------------------SADSINL
S

PF15330 // ENSGT00470000042273_0_Domain_1 (542, 732)

ILL--PLIFAVLLLLLV-----AA-----------SLLA-LRMMKQQK--KA--AGPS-
-------------PEQ------GMQPLEG--DLCYA------NLTLQPTG--TSHG-SSQ
KKACTKPSSSALENQKE-VDYVTMAS---------------------FP------KENIS
YAALSWEL-LDQEPTYSNTDVL-VTHVPRRNPE----ESM--EYSTIRKP----------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MRPLVL----------LWSCLVL-------------------------------
-------PGYE--------------ALK

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 336)

GPK-EVSG------FEGDSVSLQCSYEKKVRG
R-RKYWCRK---GGLIL----SRCS-DIVYS-E-QNQ--EVVRGRMSIRDRPRELSMTVT
MRNLTVKDSGKYWCGIDRLGF-------------DESF-E--VSL--IVFPGRRDSPT-P
TGTCCPTSPNPSFQPLTATRI---LQPKAIAWQTQLPE--LTSPGLHPTVVTVKQGKTEV
KAPVFTEEAPAW-SSGTSQVLPGTSPYAGNAPHTTTPAWSAGTSP-SPGTSPYAGS-SP-
-----H-TATS-PHA----GSS-----RP-VIWPL--SITPKD---STT----SRVLTSS
VSIPIVRMMAPVWVLLSLLL----A--T------GLIAFGSHMLQW-RK--KAWLAVET-
-QRN----------EKVYLP---ASPPGNNWVPEDA------MINLAAP-----PE----
---CLSNPKASTVPFTE-TQYLGQA------------------------------TEEEA
--APSLD-----AKEDEDAMAA----PPLQVSAQ---ELA-SEFISV-------------
----------------------

------------------------------------------------------------
--------------------MTQAL-----------------LHILGFQLGPRF--AEDG
SQGDRTMWLLPA-------LLLLCF-----------------------------------
-------SGCLS---L-----------T

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 316)

GPD-SVTG------TVGGSLRVWCQYESTYKG
Y-NKYWCRG---QYD------TSCE-SIVET-KGEEK--VERNGRVSIRDHPEALAFTVT
MQNLNEDDAGSYWCKIQTVWILDSW-------SRDPSA-L--VRV--YVSPATR-----T
TRPA--------------------------------------------------------
--------------TT-----------PIF---LVVNPG---------------------
----------------------------------R--NLGTG------EVL----TKNSG
FRLS--SPHFLLVVLLKL-----PLLLS------MLGAVF-WVNRPQRA--PA--GR---
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MHLSLL-V--PFLF---W------------------------------------
----I--TGC--------CTA--EDPVT

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 319)

GPE-EVSG------QEQGSLTVQCRYTSGWKD
Y-KKYWCQG---VP--Q----RSCK-TLVET-DASEQ--LVKKNRVSIRDNQRDFIFTVT
MEDLRMSDAGIYWCGITK

ENSGT00470000042273_0_Linker_0_1 (319, 542)

GGL-------------DPMF-K--VTV--NIGPAIQVPITVP
TM-------P----PITST-------------------------------T---------
---------------TI----------------FTVTTTVKETS-----------M-FP-
-------TLTS-YYS---------D-NGHGGGDS----------GGG--EDGVGDGFLDL
S

PF15330 // ENSGT00470000042273_0_Domain_1 (542, 731)

VLL--PVISAVLLLLLL-----VA-----------SLFA-WRMVRRQK--KA--AGPP-
-------------SEQ-----A--QSLEG--DLCYA------DLSLKQPR--TSPG-SSW
KKGSSMS-SSGKDHQEE-VEYVTMAP---------------------FP------REEVS
YAALTLAG-LGQEPTYGNTGCP-ITHVPRTGLEE---ETT--EYSSIRRPLPAAMP----
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MWLSIG-------LFLLCF-----------------------------------
-------QGCLS---L-----------T

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 324)

GPG-SVSG------YVGGSLRVQCQYAQSYKG
Y-TKYWCRG---PHD------KGCK-SIVET-DGSER--EKKNGRVSIRDHAGNSTITVT
MENLSEDDAGSYWCKIQTVFIWDFL-------SRDPSV-R--VKV--HVFPATT-PM-ET
TLPA--------------------------------------------------------
--------------IT-----------PFL---PLVDPG---------------------
----------------------------------Q--NLRIRS----STMLIFQLW----
SLLS--SVHFQVLVFLKL-----PLFLS------MLCAIF-WVSRKI----PE--GM---
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MRLLVL----------LWGCLLL-------------------------------
-------PGYE--------------ALE

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 319)

GPE-EISR------FEGDTVSLQCTYREELRD
H-RKYWCRK---GGILF----SRCS-GTIYA-EEEGQ--ETMKGRVSIRDSRQELSLIVT
LWNLTLQDAGEYWCGVEKRGP-------------DESL-L--ISL--FVFPG--------
--PCCPPSPSPTFQPL----ATTRLQPKAKAQQTQPPG--LTSPGLYPAVTTAKQGKTGA
EAPPLPGTSQYG---------------------------HERTS-------QYTGT-SP-
-----H-PATS-PPA----G-----SSRP-PMQLD--STSAED---ASPA-LSSGSSKPR
VSIPMVRILAPVLVLLSLLS----A--A------GLIAFCSHLLLW-RK--EAQQATET-
-QRN----------EKVCLS---HLT----------------------------------
-------------------------------------------------------TEEKE
--APSQA-------PEGDVISM----PPLHTSEE---ELGFSKFVSV-------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MRSLVL----------LWGCLAL-------------------------------
-------PGYE--------------AMK

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 349)

GPK-EISG------FEGDTVSLKCTYETKLRE
H-RKYWCRQ---VGLVV----SRCS-GTIYT-R-DEQ--EVGQGRTSIRDRRQELSVTVT
MRSLTLQDAGIYWCGIDRLGF-------------DDGF-Q--VKL--TVFPGKGDSAS-Q
AGVCCPPSPSPSFQPLTATRS---LQPKAHAWQTQPPE--LTSPDLRPTVATAEQEKSGV
KVPAFIGATSAP---------------------------SAGTSR-FPGASRNAGS-PP-
-----H-TATS-PHA----GSS-----RP-AIWLP--T-TPKD---PGLD-PGRSSSQPR
ASIPAVRMLAPALVVLGLLL----A--A------GLIAFGSHILRR-WK--NACPMTET-
-PQN----------EKVYLP---TSPLGNGWAT-DA------MINLAAP-----PE----
---PLSSPTLSADPCAE-VQYLNQT------------------------------TEEAL
C-------------QHAEDLVA----SPLQIPEE---ELRFSEFISV-------------
----------------------

------------------------------------------------------------
----------------------------------------------------------EW
GGQ--------N-F--ALFC----------------------------------------
----F--SGC--------FSAPPVPALT

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 335)

TQG-EVRG------TLGGSVSVPCQYQKVYQG
N-PKYWCRG---AE--W----STCS-KVIET-AGLEA--EVKRGSVSIQDNHTLNTFTVT
MENLTLGDAGTYWCGINKSGR-------------DRNS-R--VNV--MVLPALSTAVMVT
TGSL--------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
-----MPLLM-L-Y--PLLF---W------------------------------------
----L--SGY---------SI--ATDISG

PF07686 // ENSGT00470000042273_0_Domain_0 (210, 318)

PM-TVNG------PERGSLMVQCVYNSGWET
Y-LKWWCRG---AT--W----YGCK-ILVKT-TGSEQ--EVKRDRVSIKDNQKNHTFTVT
MEDLMQTDADTYWCGIE

ENSGT00470000042273_0_Linker_0_1 (318, 542)

RTGT-------------DLGV-T--VQV--IIDPA--------
------------------------------------------------------------
------------------------------------PVTPEETS-----------N-SP-
-------TLTG-HHL---------DK---------------------------RHNLLKL
S

PF15330 // ENSGT00470000042273_0_Domain_1 (542, 732)

VLL--PLIFTILLLLLV-----AA-----------SLLA-WRIMKCQQ--KA--AGMS-
-------------PEQ------VPQPLEG--DLCYA------DLTQQLTR--TSP-----
QKATTKLSFSAQADQVE-VEYVAMAP---------------------FP------KEDIS
YASLTLAA-EDQEPTYCNMGPL-SSHIPSGGPE----DPT--EYSIIRRP----------
----------------------

------------------------------------------------------------
-------------------------MHRRCKTELRQNF----QSASGIRICHWLQIRWTR
SREGRAMWLSPA-L--LLLS----------------------------------------
----L--SGCF--------------SIRG

PF07686 // ENSGT00470000042273_0_Domain_0 (210, 349)

PV-SVRG------PEKGSVKVQCHYKRGWET
H-VKWWCRG---AR--W----VSCE-ILIQT-RGSEQ--EEKKDLVSIKDSHTDCTFTVT
MEGLRQNDSNIYWCGIQRRGP-------------DLGT-Q--VQL--TVDPEGAASAPAN
S-----------------------------------------------------------
------------------------------------------------------------
--------S------------------------------------------VNSNIRVSI
STHK--RNHYMLLVFVKV-----PILLI------LVGAIL-WLKGF-QR--VP--EEPG-
-----------------------DQPIYM--NFS-EL--LTKDMAA--------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------

PF07686 // ENSGT00470000042273_0_Domain_0 (190, 431)

CWS---L-----------RGPR-RVTG------VVGGSLSVQCRYKKEFID
H-IKYWCKS---PYF-------LPW-SIVKT-TKSER--EVRKDRVSIRDHPANLTFTVT
LESLRMDDAGTYCCGIDK-S-------------XXXXX-X--XXX--XXXXXXXXX----
ASLT--------------------------------------------------------
---------TTKTSTTTN-R---------M---SALSSTAPATV-----------S----
--------AT---Y-----IASSQEESQPVLD----------------------------
-QX-----XXXXXXXXXXXXXXXXXXXX------XXXXXX-XXXX----X--X--GKN--
-------------PE------V--------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MRPLVL----------LWGCLVL-------------------------------
-------PGYE--------------ALK

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 338)

GPK-EISG------FEGDTVSLQCTYEEKMKE
Y-RKYWCRQ---GGILV----SRCG-DIVYT-N-QDQ--KVTRGTMSIRDSPQVLSMTVT
MRDLTLKDSGKYWCGIDRLGR-------------DESF-E--VTL--IVFPGKRDSAV-P
AGTRCPSSPTPSLQPLTPTRS---LQPKPKAWQTQLPE--PTPPGLHPTVVTAKQGKTGV
KAPVFTEAAPAR-SAGTSQVPPGISPYAGSSPHTATPARSAGTSQVPPGISPYAGR-SP-
-----H-TATS-PHA----GSS-----RP-LIWLP--LTTPQD---SRAV-A-SSVSKPS
VSIPMVRMMAPVLVLLSLLL----A--A------GLIAFGSHMLRW-RK--KAWLATET-
-QKN----------EKVYLE---TSLPGNGWTPEDL------TIDLAVS-----PG----
---CLGNPDPSAVPPPE-TQNLSQS------------------------------TE-EA
A-ARSLDN-DDAAAAEEGVMAP----PPLQTSAE---ELAFSEFISV-------------
----------------------

------------------------------------------------------------
-----------------------------------------------------------M
IPRVIRLWLPSA-------LLLSQV-----------------------------------
-------PGCVP---L-----------H

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 318)

GPS-TVTG------TVGESLSVSCQYEEKFKT
K-NKFWCRVSL---K-----G-LCK-DIVKT-SSSE---EARNGRLTIRDHPDNLTFTVT
FESLTLEDADTYLCVVELPFFH-------------KFF-M--IEL--SVVPSEDP--D--
----------------------------------------------------LCG-----
------------------------------------------------------------
--------------------------------------------------------HRPG
SLLS--SPHFWVLVSLEL-----PLFLS------MLGAVL-WVNRPQRW--SG--R----
-----------------------SSP-----RPCYE------NQ----------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MWRPPA-L--LFLS----------------------------------------
----L--SGCF--------------SIY

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 318)

GPE-SVRG------PEQGSVAVKCHYDQKWET
H-NKWWCRG---EN--W----DLCN-ILIRT-RGSEQ--EEKSDRVSIRDNQREHWFTVT
MEGLRRDDTDIYWCGIQKFGT-------------DLGV-R--VKV--IIDPVGATSTSTG
T-----------------------------------------------------------
------------------------------------------------------------
--------S------------------------------------------SNSNTGVTS
SSHK--RTHYILLVFVKV-----PILLI------LVGAIL-WLKGF-QR--VP--EETW-
-----------------------RQPVYM--NLSSDL--LTKD-----------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MWLLLP-------LLLFCL-----------------------------------
-------PGCLS---L-----------T

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 318)

GPS-SITG------PMGGSLLVQCRYEKMYKG
H-NKYWCRG---QHD------TTCE-SIVEI-EGGAQ--EERNGRVSIRDHPEALTFTVT
IENLNADDAGSYWCKIRTIWILDVW-------SRDPSV-L--VKV--CVSPATTTPR-RA
SQPA--------------------------------------------------------
--------------IP-----------PVF---PLVNPR---------------------
----------------------------------Q--NSSAK------DMS----TQHPG
SLLS--SVHFLLLIFLKL-----PLFLG------MLGAIL-WVNRPQRS--SV--GRQ--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
-----MP-LLML-Y--PLLF---W------------------------------------
----L--SGY---------SI--ATDISG

PF07686 // ENSGT00470000042273_0_Domain_0 (210, 349)

PM-TVNG------LERGSLIVQCVYKSGWET
Y-LKWWCRG---AI--W----HGCK-ILVKT-TGSEQ--EVKRDRVSIKDNQKNHTFTVT
MEGLMQTDADTYWCGIERTGT-------------DLGV-T--VQV--T

ENSGT00470000042273_0_Linker_0_1 (349, 542)

VDPAST----AA
PT--------------TST-------------------------------S---------
---------------TT----------------FTAPVTPEETS-----------N-SP-
-------TLTG-HHL---------DK---------------------------RHNPLKL
S

PF15330 // ENSGT00470000042273_0_Domain_1 (542, 732)

VLL--PLIFTILLLLLV-----AA-----------SLLA-WRIMKCQQ--KA--AGMS-
-------------PEQ------VLQPLEG--DLCYA------DLTLQLTR--TSP-----
QKATTKRSFSGQADQVE-VEYVAMAP---------------------FP------KEDIS
YASLTLAA-EDQEPTYCNMGPL-SSHIPSGGPE----DPT--EYSIIRRP----------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MWQFSA-L--LLFF----------------------------------------
----L--PGC--------CTA--QDSVT

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 319)

GPE-EVSG------QEQGSLTVQCRYSSYWKG
Y-KKYWCRG---VP--Q----RSCD-ILVET-DKSEQ--LVKKNRVSIRDNQRDFIFTVT
MEDLRMSDAGIYWCGITKGGP-------------DPMF-K--VNV--NIDQAPKSSMMTT
TATVLKSIQP--------------------------------------------------
------------------------------------------------------------
-------------SAE------NTGK---------------E--QVTQSKEVTQSRPHTR
SLLS--SIYFLLMVFVEL-----PLLLS------MLSAVL-WVTRPQRC--FG--RGEND
LVKT-----HS-----------------P--VA---------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
-----------------------------------------------------------M
TLRHVAVWLPSA-------LLLLQI-----------------------------------
-------PGCFL---L-----------S

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 317)

SPS-TVTG------TVGGSLSVQCQYEEEDKA
R-DKYWCRG---SLA-----V-LCD-KIVET-KDSVR--EVRSGRVTIRDHPANLSFTVT
LESLSLQDTGSYWCGVDAPWQED--------P--AVKF-M--V----SVLPG---ETGS-
------------------------------------------------------------
---------FLEGIRSTT-G---------P---PL--FLSVYT---------------W-
-------R-----------------------ST-------------TRGDTSN-PSPQPR
PLFS--SIHFLLLVFLKV-----PLLLS------MLSAIL-WVNRPQRG--SG--W----
-----------------------RS------HPEYE------NQ----------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---

PF07686 // ENSGT00470000042273_0_Domain_0 (184, 350)

CY--KGT----------------------QRSC------RSLESLTVTCDYGPAV--
--QKWWCRG---ET--L----NGCW-NWVKT-SGAEP--VVRKDRVTIRDDQSQHRFTVT
MEQLMDSDAGMYWCGIERVGH-------------YVGF-Q--VRV--TISPAAASTEETT
DA----------------------------------------------------------
------------------------------------------TS----------------
------------------------------------------------------VTRALS
NTLL--PVISAVLL-LLL-----AA-----------ALLA-WRKLKRQR--TA--TGVP-
-------------PEP----------AQE--EVSYT------HLSLRP------------
------------------------------------------------------------
---------HDPEPIYANADAG-AGPSADRISE----VAT--EYSSIRKLR---------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MRLTWA-L--LLLS----------------------------------------
----L--PGCF--------------SLR

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 316)

GPA-SVRG------SEGGSVTVQCHYSSRWKT
Y-NKWWCRG---RR--R----RVCS-VLVKT-RGSEQ--EEKSGRVSIRDNQTYWSFKVT
MEGLRQDDAGTYWCGIERSFT-------------DPGV-P--VKL--IIDPAGMVNLTSK
----PLD-----------------------------------------------------
--------------------------------------G-------------------P-
--------S------------------------------------------DESSFGVSF
GSHS--RTHYLLLAFVKV-----PILLI------VAGAVL-WLKGL-QR--VP--QE---
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
-----------------------------------------------------------M
MARAWASWRPSA-------LLLLLV-----------------------------------
-------PGCFA---L-----------S

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 316)

GPH-TVAG------PLGGSLSVQCGYEVEHRT
L-NKYWCRA---PWT-----I-RCA-KIVET-RGSAG--KLRNGRVSIMDHPANLSFTVT
LENLTEDDAGTYWCGVDLPWLRD--------L-HDPFI-K--VEV--SVFPALTT-----
----------------------------------------------------TAS-----
---------SPQSSMGTW-G---------P---PT--KLHVHT---------------W-
-------P-----------------------NP-------------TREDSPD-PSPHPG
SLLS--SPHFLLLVFLKL-----PLLLS------MVGAVL-WVNRPQRS--SR--S----
-----------------------RRS-----RPEGE------NQ----------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MRPLVL----------LWSCLVL-------------------------------
-------PGYE--------------ALK

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 340)

GPK-EISG------FEGDSVSLQCTYEKRVRG
H-RKYWCRE---GGLVL----SRCS-DIVYS-S-QNQ--DVARGRMSIRDSPRELSMTVT
MRDLTLKDSGKYWCGIDRLGF-------------DESF-E--VSL--IVFPGKRDSPI-P
TGTCCPSTPNPSFQPLTATRS---LQPKAKAWQTQVPE--LTSPGLHPTVVTAKQGKTGV
KAPVFTEVALLAGSAGTSQVLPGTSPYAGSSPHTATPARSPGTSP-SPGTSPYAGS-SP-
-----H-TATS-PHA----GSS-----RP-GIWLA--PTTAKD---SKA----GSVSKAS
VSIPMVRMMAPVWVLLSLLL----A--A------GLIAFGSHMLQW-RK--KAWLATGT-
-QGK----------EKIHLP---ASPPGNSWAPEDA------MINLAAP-----PE----
---YLGNPKPSAVPSTE-TQQLGQT------------------------------TEEEA
--APPLD-----SE--EDKMAA----PPLQMSAE---ELAFSEFISV-------------
----------------------

------------------------------------------------------------
-----------------------------------------------------------M
TARAWASWRPSA-------LLLLLV-----------------------------------
-------PG-FA---L-----------R

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 318)

GPS-TVDG------PVGGSLSVQCWYEEEHKT
L-NKYWCRP---PRV-----L-RCD-KIVET-KGPAG--E-MNGRVSIRDSPENLSFTVT
LENLTEEDAGTYWCGVDTPWHQE--------L-RDPYA-Q--VEV--SVFPGEPLLF---
--------------------------------------------------LAPAS-----
---------SSQSSMGTS-G---------P---PP--KLPVHT---------------W-
-------P-----------------------SV-------------TRKDSPE-PSPHPG
SLFS--NVRFLLLVLLEL-----PLLLS------MLGAIL-WVNRPQRS--SR--S----
-----------------------RQS-----WPEGE------NQ----------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------

PF07686 // ENSGT00470000042273_0_Domain_0 (190, 350)

SLS---L-----------SGPS-TVEG------TVGGSLTVQCRYEKKHR-
K-IKYWRRE---ILD-------LL------T-VLTTE--SERNGHVSIRDHPANLTFTVT
LENLAKDDEGTYECGIDVPW-------------LDPTS-K--VVV--SVFPXXXXX----
XXXX--------------------------------------------------------
---------XXXXXXXXX-X---------X---XXXXXXXXXXX-----------X-XX-
-------XXX---X-----XXXXXXXXXXXXX----------------------------
-XL-----HVLLS-LLAIL----LLLLG------GTSLLA-WSRR----WTRA--GGNPE
PPQN---------PRQ-----GPQQT-----EPCYA------NMELQT-----QR-----
---LWAE--PEWPRQAE-TEYSTAG----------------------AP------REELH
YSSIVVN--NQSQDSK-DTIPH------QRPPP----QEP--AYSVIRKT----------
----------------------

------------------------------------------------------------
-----------------------------------------------------------M
TLKDQAARLPSA-------LLFLLV-----------------------------------
-------PGSLS--

PF07686 // ENSGT00470000042273_0_Domain_0 (195, 343)

-L-----------SGPR-TVTG------TIGGSLSVQCRYDEEYRE
H-KKYWCQN---SKW-----P-PWRRKIVET-TESER--EASRGRVSIRDHPANLTFTVT
LESLTEADTGTYCCGIDTRWSGG--------VLRDSTF-Q--VEV--SVLPGETQAA---
-----------------------------------------------------PT-----
---------PK-IFTSTP-G---------P---PT--TLPATT---------------R-
-------SST------------------------------------TRQETAD-PSQHHR
SLLS--SVRFLLLVFLEV-----PLLLS------MLSAVL-WVNRPLRG--CG--Q----
-----------------------RRS-----QPDCE------NQ----------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
-------------M----FSLLSWV-----------------------------------
---LI--PGYWA---L-----------

PF07686 // ENSGT00470000042273_0_Domain_0 (208, 345)

SGPN-EVHG------DVGASLSVKCCYDKDYEN
Q-SKYWCKF---KTFLKVFSELYCA--VLIR-SELDK--KVEDSRISIQDSKKTLCFKVN
MNNLTLKDAGLYQCGITHRIFPDS------------TH-N--IKV--IIYQDPEEESTI-
TEQP--------------------------------------------------------
---------E-KISNTEQ-D-------------ERLSSTKTS------------------
---------D---P--------------------G--RIAEDTDESSSSPIPT-E-----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
-------MRFLL----------LWGWIII-------------------------------
-------PGYG--------------AMVG

PF07686 // ENSGT00470000042273_0_Domain_0 (210, 344)

PK-EVSG------PEGSSLSVQCSYEDKHRE
R-KKYWCKN---NGLIF----SPCA-TVIIT-E-AGK--EETNGEVSIKDNPQNGTFTVI
MRKVTQKDAGKYQCGISIFGF-------------DEIF-E--VTV--VVFSGLES-----
-----SDSLNPSLQPP----STRSDQQGVKVWETRSPE--LHIPQTFPSASLYKKGPAGS
KSSVKSDHPHPGKDKA-SNIH-------KCGDQGCSPSKGPRDSSD----------KNP-
--RSLLCPFLS-PFS------------LS-NI----------------PL-PPSSLSVPR
ISIPLIRILAPCIILLLLLV----VAIA------TLLILLARR-----K--KAQLVVES-
-GKN----------GQFHYS---NSVKESQD-----------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MWLSPA-L--LLLS----------------------------------------
----L--S--------------------------------------

PF07686 // ENSGT00470000042273_0_Domain_0 (227, 349)

SVKVQCHYKRGWET
H-VKWWCRG---AR--W----VSCE-ILIQT-RGSEQ--EEKKDLVSIKDSHTDCTFTVT
MEGLRQNDSNIYWCGIQRLGP-------------DLGT-Q--VQL--TVDPEGAASAPAS
S-----------------------------------------------------------
------------------------------------------------------------
--------S------------------------------------------VNSSIRVSI
STHK--RNHYMLLVFVKV-----PILLI------LVGAIL-WLKGS-QR--VP--EEPG-
-----------------------DQPIYM--NFS-EL--LTKDMAA--------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MYLLML-L--PLLF---Q------------------------------------
----L--SGS--------------SPVT

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 349)

GPK-ALRG------QERGSLTVQCRYTPGWES
H-GKWWCRG---AD--W----SSCK-ILVQT-TASEP--EVKRDRVSIRDDRENRTITVT
TEQLRLDDAGIYWCGIARVGT-------------DHGA-Q--VRV--T

ENSGT00470000042273_0_Linker_0_1 (349, 543)

VDPAPTTVPTT-
----------------TSA-------------------------------I---------
---------------NT----------------FTAPVTSGD-------------D-SL-
-------NMTS-HGP------------NG------------------------SSIFGNL
ST

PF15330 // ENSGT00470000042273_0_Domain_1 (543, 726)

LL--PLIFAVLLLLLV-----VA-----------SVVV-WRMVKQQK--KG--AATS-
-------------PE---------QPLES--DLCYA------NLNLQEPN----SG-SSQ
RKASTQPSSSAQGRPKD-VEYVTMAP---------------------FP------REDIA
YAALSLGDNENQEATYSNMGDL-LAHDPSRSHE----EPT--EYSAVKKA----------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------

PF07686 // ENSGT00470000042273_0_Domain_0 (204, 344)

SAAITGPK-AVRG------LEQGSLTVQCRYGPGWET
H-VKWWCRG---AH--W----GSCK-FVVET-TGSEK--EVKKDRVSIKDNQKNRSFTVT
MEKLRLNDADTYWCGIERFGT-------------DLGV-P--VKV--TVDPXXXXXXXXX
--------------XXXXX-------------------------------X---------
---------------XX----------------XXXX-----------------------
-------------XX----------------------------------------XXXXX
XXXX--XXXXXXXXXXXX-----XX-----------XXXX-XXXXXXXX--XX--AEIS-
-------------AEQ------VLQPLES--DICYA------NLSLQQTG--NSSG-SSR
KKASEL--SSAQANQVE-VEYVTMAP---------------------FP------REDIA
YAALSLDT-SDQEPTYSNMGYL-STHVPSSSHE----EPT--EYSTIRKP----------
----------------------

------------------------------------------------------------
------------------------------------------------------------
-------------M--KVLCGLIWT-----------------------------------
---LS--QVCWA---L-----------E

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 336)

GPQ-RVSA------PHGSSISLQCKYTKEDKE
Y-VKFWCRE---QSHRFC----CHS-HLVQT-TGSEA--EVKVNKTSIKDNHIFHEFRVT
IENVTEVDAGTYLCGVERW-------------NYDISH-Q--VEI--IITTASLSPF---
--SV--------------------------------------------------------
---------L------VR-NRE--------------------------------------
---------Q---E-------TN---HST-------------------GSTIA-PESIQS
SNTD--F---LFTVILKI-P---ICLI-------MIAAVV-WVNIWYKK-GRCPRTKTQQ
--------------------------N-E--KSNFK------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
---GRTMWLPPA-L--LLLS----------------------------------------
----L--PGYL--------------S

PF07686 // ENSGT00470000042273_0_Domain_0 (207, 319)

IQGPK-FVRG------SERGSVTVECRYKPRWET
Y-TKWWCQG---AS--W----ESCK-ILLQT-TGSEQ--EVKTDRMSIRDNQSNHSLTVT
MTQLRRDDTDIYWCGIERLGP-------------DLGV-Q--INV--TVDPEARATVSKE
TK-LPI------------------------------------------------------
----------------------------------------------------------P-
-------GE------------------------------------------GGLLGSDHS
ASSH--RTRYMLLVFVKV-----PVLLI------LVGAVL-WLK----------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------LSGQVL-------GSDLCF-----------------------------------
-------PGCWS--

PF07686 // ENSGT00470000042273_0_Domain_0 (195, 345)

-L-----------TGPS-SVAG------TMGSSLHVRCQYEKAYKG
H-NKYWCRG---KYG------TVCR-KIVET-KGEEK--ERRNGRVSIRDQADNLTFTVI
MENLSTNDAGSYWCRIQTVWILDVL-------SWDPSV-Q--VEV--SVSPGKSSAAGKR
VGLG--------------------------------------------------------
--------------QR-----------FCF---QELPVGSVGG---------------F-
-------D--------------------------P--ELSRGR----QLISS--HCVSHR
SELS--NVHFLLLVFLKL-----PLFLG------MVGAVL-WVNRPQRR--PG--GRKRQ
LDQG---------GRP-----CSVLS----------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
-----------ARG--WCSWRQSTA-----------------------------------
---LC--LP

PF07686 // ENSGT00470000042273_0_Domain_0 (190, 353)

GRA---V-----------RGPG-TVVG------YIGESLSVSCSYQKGYEK
Y-PKYWCYP---GR--LNT-CLYKT-HIVIT-SEKQP--WAQWHRTSIRDNRTERVFTVT
MRDLTAGDAGTYRCGVQTSL------------WQKDVADM--VRV--TVFSVPASRADTA
LPRT--------------------------------------------------------
---------T------TQ---PLPM--GAN---APIGTPAPAT---------------Y-
-------TAP---G---------TD-------T--------------------APDHRC-
---S-----LPLFPLLAG-LQM-LALL-------AMSAAV-L----WLN-LR--------
SGCT---------RSR------P-------------------------------------
------------AAPHR-------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------------MR--LLPLLCCTA-----------------------------------
---LC--LP

PF07686 // ENSGT00470000042273_0_Domain_0 (190, 350)

GRA---V-----------RGPG-TVVG------YIGETLSVSCSYQKGYEK
Y-PKYWCYP---GR--LNT-CSYNT-HIVIT-SEKQP--WAQWHRTSIRDNRTERVFTVT
MRDLTAEDAGTYRCGVQTSL------------WQKDVADM--VRV--TVVSEN-SKSSAS
SFTS--------------------------------------------------------
---------A------VT---PGPI--LG------------PT---------------W-
-------KPL---Q---------QE-------TAE----------Q--TARPTSPGDLSE
GQLD--IVMGILIPCIAV-V---LFFL-------TLAATI-LVILSWKR-KKALAGAPIE
MGSI---------RGT------ANV---E--VLQYV------DISHVG-----M-E----
QSRLDSNVRAAPASPQAATEYSEVKK---------------------PCQNLEG-NTESL
YAQVCKIPPEEQEQLYANMAPR------QQRAA----Q----------------------
----------------------

------------------------------------------------------------
-------------------------MCTRCKLGPGRAS----RVQLGSAFA-TDADQVMR
SREGRAMWLSPA-L--LLLS----------------------------------------
----L--SGCF--------------SIH

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 349)

SQE-SVRA------PEQGSVTVQCHYQQRWET
Y-VKWWCRG---VR--W----DSCT-ILVQT-RGSEQ--EEKRDRVLIKDNQRDHVFTVT
MEGLRRNDTDIYWCGIKRLGT-------------DLGT-Q--VKV--IVDPVGAASTPAS
SS---S------------------------------------------------------
--------------------------------------K-------------------L-
--------T------------------------------------------TNRNMGVFI
SSHK--RTHYVLLVFVKV-----PILLI------LFGTIL-WLKES-QR--VP--EKPW-
-----------------------EQPIYM--NLSSKH--LNKDMAA--------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MRLLVL----------LWGCLVL-------------------------------
-------PGYE--------------ALE

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 319)

GPK-EISR------FEGDTVSLRCTYREELRD
H-RKYWCRK---GGLLF----PRCS-GTIYA-GKEGQ--ETTEGRVSIHDNRQELSLIVT
LWNLTLQDAGKYWCGVEKRGP-------------DESL-L--ISL--FVFPG--------
--PCCPPSPSPTFQLL----ATTRLQPKAKTQQTQPPG--LTSPGLYPAGTTAKQGKTGA
EATPFPGTSRYG---------------------------HERSS-------QYAAT-SP-
-----H-AATS-PPA----G-----SSRP-PKQLD--STSAED---ASPA-LSSGSSKPR
VSIPMVRILAPVLVLLSLLS----A--A------GLIAFSSHLLLW-RK--EARQDMET-
-QRN----------EKVYLS---HLPLGNGRDTEDA------VINIAGS-----MG----
---PLTIPEPSPGLHTE-IQYLSQT------------------------------TEEEE
--APSQD-------PEGDVISM----PPLYTSEE---ELGFSKFVSV-------------
----------------------

------------------------------------------------------------
-----------------------------------------------------------M
IPRVMAVWLPSA-------LLLLQV-----------------------------------
-------PGCVP---L-----------R

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 348)

GPS-SMTG------TVGESLRVRCQYEEKHKA
N-SKTWCRGSL---L-----P-YCR-NIVKT-RASK---EARNGRVSIRDDPATLTFTVT
LDNLTLEDAGTYMCGITP------------SLGIDSYS-K--VVV--SVVPGKPLMSW--
----------------------------------------------------HSE-----
---------SQPNRTNTL-G---------S---LT--SSLVHT---------------Q-
-------PS----------------------VT-------------TEDTTPG-PSPHPR
SLLS--SIYFQLLVFLEV-----PLLLS------MLSAVL-WVNRPQGC--SG--E----
-----------------------KRH-----CPDYE------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------AWLGSD-R--CMYL---C------------------------------------
----F--SGY--------SSV--GSA

PF07686 // ENSGT00470000042273_0_Domain_0 (207, 335)

LSGPG-KVSG------PEWGSLTVQCHYDSGWES
Y-RKWWCRG---AH--W----SSCK-IVIVT-SGSED--EVKIDHLSIRDSHKDLRFTVT
MEDLRKDDADTYWCGIERSGT-------------DLGV-Q--VKV--IITPGERVWVFGC
VSQ---------------------------------------------------------
----------------------------------------AVLC-----------C-PP-
-------AVSG-HQE---------RSRASQC---------------------GWDTWWEK
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MWLLPA-------LLLLCF-----------------------------------
-------SGCLS---L-----------T

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 316)

GPD-SVTG------TVGGSLRVWCQYESTYKG
Y-NKYWCRG---QYD------TSCE-SIVET-KGEEK--VERNGRVSIRDHPEALAFTVT
MQNLNEDDAGSYWCKIQTVWILDSW-------SRDPSA-L--VRV--YVSPATR-----T
TRPA--------------------------------------------------------
--------------TT-----------PIF---LVVNPG---------------------
----------------------------------R--NLSTR------EVL----TKNSG
FRLS--SPHFLLVVLLKL-----PLLLS------MLGAVF-WVNRPQRA--PA--GR---
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
--------------------LCLCF-----------------------------------
-------PGCLS---L-----------T

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 318)

GPG-YVTG------TVGGSLCVQCQYEQSYKN
S-KKYWCRG---QFD------TQCD-IIVEA-LGGK---KGRSDRVSITDHTDDLTMTVT
MEDLSEDDAGSYWCKIQTFWILDAW-------SRDPSV-K--VQV--YVYPGEM-LL-AP
AI----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------GLWIVTAWDKSG
SLLS--SFHFQVLVFLKL-----PLFLS------MLCAVF-WVNTL--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MHLPTL-F--LLLF---W------------------------------------
----L--SGY--------STA--GYPVTG

PF07686 // ENSGT00470000042273_0_Domain_0 (210, 316)

PG-AARG------PEQGSLTVQCRYEPGWET
H-KKWWCRG---AH--C----RSCR-ILVMT-TGSEQ--EVKKDRMSIRDSHKNHTFTVT
MEELRRDDADTYWCG

ENSGT00470000042273_0_Linker_0_1 (316, 542)

MERTGI-------------DPGV-P--VEV--TIDPATTTVS---
--------------TAAPT-------------------------------T---------
---------------NT----------------FTALVTLEKTA-----------S-SP-
-------MVTS-YQS------------GN------------------------RPGIMKL
S

PF15330 // ENSGT00470000042273_0_Domain_1 (542, 728)

VLL--PLIFAILLLLLV-----AV-----------SLLA-WRMVKRRK--NA--SGLP-
-------------PEQ------VSQPLED--ELCYA------NLTLQRTG--TSRS-SSR
KKACTEPSSSAQ---EE-VEYVTMAP---------------------FP------REEVS
YASLTLGD-LDQEATYSNTGQL-TTHIPGASHE----DPT--EYSTLRSP----------
----------------------

------------------------------------------------------------
----------------------------------------------------------MR
SREGGAMWLSPA-L--LLLS----------------------------------------
----L--SGCF--------------SI

PF07686 // ENSGT00470000042273_0_Domain_0 (208, 349)

QGPE-SVRA------PEKGFVKVQCHYKQGWET
H-IKWWCRG---AH--W----VSCE-ILIQT-RGSEQ--EEKKDHVSIKDSHTDCTFTVT
MEGLRQNDSNTYWCGIQRLGP-------------DLGI-P--VQL--TVDPEGAASAPTS
S-----------------------------------------------------------
------------------------------------------------------------
--------S------------------------------------------VNSNIRVSI
SSQK--RNHYMLLVFVKV-----PILLI------LVGAIL-WLKGS-QR--VS--EEPG-
-----------------------NQPIYM--NFS-EL--LTKDMDA--------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MWLPWA-------LLLLW------------------------------------
----V--PGCFA---LR------GFALR

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 318)

GPS-TVDG------PVGGSLSVQCRYEEKHKT
F-NKYWCRP---PRV-----LR-CA-KIVET-EGPAG--K-MNGRVSIMDCPQNLSFTVT
LENLTEEDAGTYWCGVD

ENSGT00470000042273_0_Linker_0_1 (318, 554)

TPWHQDL---------YDPYA-Q--VEV--SVFPAST-SMTPT
SITA--------------------------------------------------------
---------A-KTSTITT-V---------F---PPVSSTSLFA---------------V-
-------SAT---H-----STSNWGENEEVVS----------------------------
SQLP---------

PF15330 // ENSGT00470000042273_0_Domain_1 (554, 730)

LLLSL-LALLLLLLM------GASLLA-WRMFWK--RIKA--GEHSE
LSQN---------PKQ-----AAEQS-----ELHYA------NLELLS-----WP-----
---LQEE--PAPPREVQ-VEYSTVA----------------------AP------REELH
YASVVFD--S-----NTNRIAA------QRPRE----KEPDSHYSVIKKT----------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------SVALRPE

PF07686 // ENSGT00470000042273_0_Domain_0 (212, 348)

-EVMG------Q-WKKLTVTCDYNIEYKK
H-RKWWCRK---TV--L----MHCH-NRVHT-TGAEQ--VVRKNRVTIRDDQGQHRFTVT
MERLRDNDAGTYWCGVDTDKF-------------DLAF-P--VRV--TIAPXXXXXXXXX
XXXXX-------------------------------------------------------
----------------X----------------XXXXXXXX-------------------
--------------------------------------------XXX--XXXXXXSLLSS
VQFL--LLVFLKVPLLLF-----LM-----------GALV-WASWPQRG--PR-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MWLPWT-------LLLLW------------------------------------
----V--PGCFA---L-----------S

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 319)

GPH-TVAG------PLGGSLSVQCGYEEEHRT
L-NKYWCRA---PWT-----IR-CT-KIVET-RGSAE--KVGNSRVSIKDHPANLSFTVT
LENLTEDDAGTYWCGVDT

ENSGT00470000042273_0_Linker_0_1 (319, 554)

PLLQDL---------RDPFI-K--VEV--SVFPAST-SVTPT
SVTA--------------------------------------------------------
---------A-RISTITT-A---------F---PPVPSTTLLT---------------V-
-------SAT---H-----STSIQGDNEEVVN----------------------------
LQLP---------

PF15330 // ENSGT00470000042273_0_Domain_1 (554, 731)

LLLSL-LALLLILLV------GASLLV-WRMFQK--WVKA--GEHSE
LSQN---------HRQ-----AAEES-----EQHYA------NLELLT-----WP-----
---LQEE--PTPPTQVE-VEYSTVA----------------------AP------REELH
YASVVFD--SRTQNSEANRIAA------QRPRE----EEPDSNYSVIRKT----------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------T

PF07686 // ENSGT00470000042273_0_Domain_0 (214, 318)

VTG------LVGGSLTVWCRYQEGWES
S-EKYWCRG---KV--WE----SCT-IIIST-SKSGG--ERRNDRVSIKDNHQGHIFTVT
MNRLQEGDAGIYWCGMKSI-------------WLDPKH-L--VNV--TISPARTSLLP--
-RSP--------------------------------------------------------
---------F------QK-KIP-------------------TL---------------C-
-------TSP---P-------PQKSAMAAGRGMGN----------G--GAGER-TGEPVR
SSLE--F---LLPLVFGV-L---LVVL-------VGVSIA-WRMVRQRE-GSGAGEEEER
--------------------------K-D--VSTWM------SARHLK-----LN-----
--MSKTELLIFPPKPGPLPDFSTVDG---------------------TTILPVS-RARNL
GVILDSS-----------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
---MWLPQLDLM-R--VISA---K------------------------------------
----S--QGY---------SI--AT

PF07686 // ENSGT00470000042273_0_Domain_0 (206, 319)

QITGPT-TVNG------LERGSLTVQCVYSSGWET
Y-LKWWCRG---AI--W----HDCK-ILVKT-TRSEQ--EVKRDRVSIKDNRKNHTFTVT
MEDLMKTDADIYWCGIEKTGT-------------DLGV-P--VQV--TIDPA--------
------------------------------------------------------------
------------------------------------PVTQEETS-----------S-SP-
-------TLTG-HHL---------DN---------------------------SGRNVPR
AGTA--AAGG--------------------------P------LLCRPD--PA--AGRN-
-------------LPP------KGYHEAL--LLCPG------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MWLPWA-------LLLLW------------------------------------
----V--PGCFA---L-----------SKCR

PF07686 // ENSGT00470000042273_0_Domain_0 (212, 318)

-TVAG------PVGGSLSVQCPYEKEHRT
L-NKYWCRP---PQI-----FL-CD-KIVET-KGSAG--K-RNGRVSIRDSPANLSFTVT
LENLTEEDAGTYWCGVD

ENSGT00470000042273_0_Linker_0_1 (318, 554)

TPWLRDF---------HDPVV-E--VEV--SVFPAST-SMTPA
SITA--------------------------------------------------------
---------A-KTSTITT-A---------F---PPVSSTTLFA---------------V-
-------GAT---H-----SASIQEETEEVVN----------------------------
SQLP---------

PF15330 // ENSGT00470000042273_0_Domain_1 (554, 730)

LLLSL-LALLLLLLV------GASLLA-WRMFQK--WIKA--GDHSE
LSQN---------PKQ-----AATQS-----ELHYA------NLELLM-----WP-----
---LQEK--PAPPREVE-VEYSTVA----------------------SP------REELH
YASVVFD--S-----NTNRIAA------QRPRE----EEPDSDYSVIRKT----------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MWQFPA-L--LFLF----------------------------------------
----L--PGC--------CTA--QDSVT

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 336)

GPV-EVSG------QEQGSVTVQCRYDSGWKY
Y-KKYWCQG---AH--Q----KSCE-ILVET-DKSEQ--LVKKNRVSIRDDQTDFIFTVT
MEDLRMIDAGIYWCGITKVGQ-------------DLFF-R--VNV--NIDPAPKSSVMTT
IATVLKSIQP--------------------------------------------------
------------------------------------------------------------
-------------TTE------NTGK---------------E--QVTQSKQVTQSRPHTR
SLLS--SIYFLLMVFVEL-----PLLLS------MLSAVL-WVTRPQRC--FG--RGEND
LVKT-----HS-----------------P--VA---------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MVLSPA-------LLLLCL-----------------------------------
-------PGCLS---L-----------TC

PF07686 // ENSGT00470000042273_0_Domain_0 (210, 320)

PR-SVTG------TVGGSLHVQCHYEKSYEA
N-NKYWCQG---NDD------IECR-TIVET-KGKE-----RNGRVSIRDDAGDHTLTVT
MENLSEDDAGSYWCKIQTYWIWDSL-------SRDPSV-L--VKV--YVSPATT-PM-ET
TLPA--------------------------------------------------------
--------------TT-----------STF---PLVNAG---------------------
----------------------------------Q--SLNVST----KKMFIPQLW----
SLLS--SIHFLVLVFLKL-----PLLLS------MLCAVF-WVNRP--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
-----------------------------------------------------------M
GGRITCLLPALF-L--LV------------------------------------------
---------I--------PGS---SAIS

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 349)

GPR-AVRG------VEQGSLTVRCQYDPGYEP
Y-VKWWCRG---AD--W----SSCC-FVVKTNLGSEK--EVKQGRVSIKDNWKDRSFTVT
MEKLRVDDSDTYWCGTERTGV-------------DLGD-D--VDV--TIDPAPTV-----
-----SISTR--------------------------------------------------
--------------------------------------------A-------TSSA-NM-
--------FTA-SVAP----EEN---------------------------------QRQL
PLLG--SVHFLVLVFLKV-----PLFLG------MLGAVL-WVNRPLRS--SR--GKPQE
NQQ----------------------PPCS--STLSR----EKDPQTEEKGIFLRQ-----
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------

PF07686 // ENSGT00470000042273_0_Domain_0 (190, 348)

SG--------------ALTGPK-EVSG------FEGASVSVQCSYKEELKQ
H-QKYWCKE---VGFFL----SRCS-HTVYS-GADGQ--EVTSGKVTIRDNLRELAFTVT
LRDLALEDGGKYWCGVRRLGT-------------DDTV-K--VSL--VVFPG--------
--PCCLLSPPPSFQPL----ATRSLEPKANAWHTQSPE--LTSPGLHLRVTTAKQGKTGA
TAPPHTGTSLRV---------------------------PAGP--------QYTEA-PP-
-----H-AATS-PSA----GSS-----HL-TMQLD--STSAKG---TSPI-PSS-SSKSR
VSVPLVRILAPVLVLLGLVL----A--A------SLVAVGSCVLRR-RG--E--------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------C--------YTA--QDPVT

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 317)

GPE-EVSG------QEQGSLTVQCRYDSGWKD
Y-KKYWCQG---VP--Q----RSCD-ILVET-DKSEQ--LVKKNRVSIRDNQRDFIFTVI
MEDLRMSDAGIYWCGITKVGT-------------D-------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MWLPWA-------LLLLW------------------------------------
----V--PGCFA---L-----------R

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 324)

GPG-TVDG------HVGRSLSVQCHYEEEHKT
L-NKYWCRP---PRV-----LP-CD-KIVET-KGPAG--K-MNGRVSIRDCPANLSFTVT
LENLTEEDAGTYWCGVDTPWHQD

ENSGT00470000042273_0_Linker_0_1 (324, 554)

F---------HDPVV-Q--VEV--SMFPASM-SMTPT
SITA--------------------------------------------------------
---------A-KTSTITT-A---------F---PPVSSTSLFA---------------V-
-------SAT---H-----STSNQEENEEVVS----------------------------
SQLP---------

PF15330 // ENSGT00470000042273_0_Domain_1 (554, 727)

LLLSL-LALLLLLLM------GASLLA-WRMLQK--WIKA--GEHSE
LSQN---------PKQ-----AAEQS-----ELHYA------NLELLS-----WP-----
---LQEE--PA-PREAQ-VEYSTVA----------------------AP------REELH
YASVVFD--S-----NTNRIAA------QRPQE----KEP--YYSVIKKT----------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MHLSLL-V--PFLF---W------------------------------------
----I--TGC--------YTA--QDPVT

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 320)

GPE-EVSG------QEQGSLTVQCRYDSGWKD
Y-KKYWCQG---VP--Q----RSCD-ILVET-DKSEQ--LVKKNRVSIRDNQRDFIFTVI
MEDLRMSDAGIYWCGITKV

ENSGT00470000042273_0_Linker_0_1 (320, 542)

GT-------------DPMF-K--VTV--NIGPAIQVPITVP
TM-------P----PITST-------------------------------T---------
---------------TI----------------FTVTTMVKETS-----------M-FP-
-------TLTS-YYS---------D-NGHGGGDS----------GGG--EDGVGDGFLDL
S

PF15330 // ENSGT00470000042273_0_Domain_1 (542, 731)

VLL--PVISAVLLLLLL-----VA-----------SLFA-WRMVRRQK--KA--AGPP-
-------------SEQ-----A--QSLEG--DLCYA------DLSLKQPR--TSPG-SSW
KKGSSMS-SSGKDHQEE-VEYVTMAP---------------------FP------REEVS
YAALTLAG-LGQEPTYGNTGCP-ITHVPRTGLEE---ETT--EYSSIRRPLPAAMH----
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MPLLTL-Y--LLLF---W------------------------------------
----L--SGY---------SI--ATQIT

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 349)

GPT-TVNG------LERGSLTVQCVYRSGWET
Y-LKWWCRG---AI--W----YDCK-ILVKT-TGSEQ--EVKRDRVSIKDNQKNRTFTVT
MEDLMKTDADTYWCGIEKTGN-------------DLGV-T--VQV--T

ENSGT00470000042273_0_Linker_0_1 (349, 542)

IDPAPT----PA
PT--------------TPT-------------------------------S---------
---------------TT----------------FTAPVTQEETS-----------S-SP-
-------TLTG-HHL---------DN---------------------------RHKLLKL
S

PF15330 // ENSGT00470000042273_0_Domain_1 (542, 732)

VLL--PLIFTILLLLSV-----AT-----------SLLA-WRMMKRQQ--KA--AGMS-
-------------PEQ------VLQPLEG--DLCYA------DLTLQLAG--TSP-----
RKATTKLS-SAQVDQVE-VEYVTMAP---------------------LP------KEDIS
CASLTLGA-EDQEPTYCNMGHL-SSHLPGRGPE----EPT--EYSTISRP----------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MWLPPA-L--LLLS----------------------------------------
----L--PGCL--------------SIR

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 318)

GPK-AVSC------QEWESVTLHCDYDPGWET
Y-RKWWCRG---AD--W----RTCR-ILVRT-DRSER--EVKKGRVSIRDHQSNRSFSVT
MENLRRNDTGTYWCGIEKIGV-------------DLGF-Q--VTV--TVGSGTAWKDLTA
SIPPDT------------------------------------------------------
----------------------------------------------------------R-
-------PM------------------------------------------DN--SVARV
SPFI--RTHYVLLVFVKV-----PILLI------LLGVIL-WLKEA-QK--VP--TKQW-
-----------------------SLPL---------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
--------------------MPQAL-----------------SQTPGFQLEPGF--AGDT
SERDRTMWLSLV-------LLLLYL-----------------------------------
-------SGSLS--

PF07686 // ENSGT00470000042273_0_Domain_0 (195, 345)

-L-----------TGPD-SVMG------TLGGSLSVQCQYEKKYQE
Y-NKYWCRG---NYD------ITCE-NIVET-KGKEK--EERSGRVTIRDHAVNLTFIVT
MENLTADDAGSYWCKIQKIWLLDMW-------SYDPSV-Q--VKV--SVFEAPSKTTERT
TCRA--------------------------------------------------------
--------------AS-----------AGF---LGPNTK---------------------
----------------------------------Q--NLST------EEVLT---C--SG
SLLS--SIHFLLLVFLKL-----PLFLT------LVGAVL-WVNRPQKG--CG--GSQP-
-DEK---------TPQ-----HSAPLP-G--MPCPG------I-----------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MWLLLV-L--FLPV----------------------------------------
----V--QGS--------------ALRAV

PF07686 // ENSGT00470000042273_0_Domain_0 (210, 320)

SS-AVSG------PLQGSLTVQCRYEPGWET
Y-HKWWCQG---AK--W----SDCH-ILVQT-DGSEQ--EVKGDRVSIKDNWKSRTFTVT
MEDLRWNSADTYWCGIEKSGT-------------DLGV-D--VKV--TIDPVTVQCHYSP
AW----------------------------------------------------------
---------------ET----------------FVKSWCPDRDLN-------SCRI-LV-
-------QTTG-PEL---------RKN-----------------------------Q--L
SIDQ--K---------KR-----TF-----------SMTI-WGE----------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
----------------------------------------------------------MT
QRAG-AAGLPSA-------LLLLYV----PG-----------------------------
---------CLT---V-----------S

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 317)

GPS-TVTG------TVGSSLSVQCQYEEKYKM
F-NKYWCRQ---PCL-----P-FWH-ETVET-TGSET--VVRSDRVIITDHPGDRTFTVT
LENLTAEDAGKYRCGIATILQEDGL----SGLLPEPFF-Q--VQV--LVSSSS-------
------------------------------------------------------------
---------GTENFVKTP-G---------S---P--------------------------
---------------------------------------------------TR-PGQCQG
V--F--C--HLCSFFPRV-----PLFLS------TLGAIL-WVSRPWRT--PW--T----
-----------------------EPW-----TGELT------T--PYDH----WC-----
---P-----AWRHN-------------------------------------------LPD
Y-RKDF------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MWPLPV-L--FLLI----------------------------------------
----I--QGHF---S-----------KCQDG

PF07686 // ENSGT00470000042273_0_Domain_0 (212, 317)

-VVRG------TAKGTLTTYCMYGQGWES
Y-NKWWCRG---EN--W----MSCK-ILVKT-TGSEQ--LVKKGRASIQDNASQRKFTMT
LEDLRYDDAGTYWCGIERIGS-------------DLGS-K--FSV--IIDPVSICKYASS
------------------------------------------------------------
-----------------------------------MPE--GNG-----------------
----------M-GIL---------------------------------------------
LASK--SLHFVLLTFVKV-----PRLGV------LLWTVV-GLSQG---------QRDPG
R--------------E------QSQSEQE--NHSSH------DTDAPVP-----------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
----------------SRKWTPQSL-----------------SQTPGLQRGPGF--AGDA
SQRDRTMWLSPV-------LLLLCL-----------------------------------
-------SGSLS---L-----------MG

PF07686 // ENSGT00470000042273_0_Domain_0 (210, 318)

PS-SVTG------TLGSSLCVQCRYEEVYQR
Y-NKYWCRG---QYD------TTCE-KIVET-KGEEK--EERSGRVSIRDHADHLTFIVT
MENLTADDAGSYWCRIQTVWLLDVW-------SHDPSF-H--VNV--FVSTAPSKTTGRT
TCQA--------------------------------------------------------
--------------VP-----------AAF---PGLNTK---------------------
----------------------------------Q--NLST------EELLT--CC--SG
SLLS--SVHFLLLVFLKL-----PLFLT------LVGAVL-WVNRPLRG--CG--GIKP-
-KED---------NPQ-----CSAPSP-G--RPCPG------T-----------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MQLLLL-V--PILF---W------------------------------------
----V--SGF--------STA--KDPIT

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 345)

GSS-TVSG------QERGSLTVWCRYDPHWKG
Y-KKYWCRG---AD--W----GTCA-TLVKT-DTSEK--LVEKNRVSIRDNQTDFIFIVT
MEDLRISDAGIYWCGIQKIGS-------------DPGF-K--VN

ENSGT00470000042273_0_Linker_0_1 (345, 542)

V--NVDPAPQAPTTAL
TT-------L----PITST-------------------------------T---------
---------------TM----------------FTESTAGKGTS-----------I-LP-
-------PVSS-PYS---------AVSL---------DGSGGDSDGG--EDSGGSGLLDL
S

PF15330 // ENSGT00470000042273_0_Domain_1 (542, 732)

VLL--PVISAVLLLLLL-----VA-----------SLFA-WRMVRRQK--KA--AGPH-
-------------SEQ-----VS-QSLEG--DVCYA------NLSLKQPR--PSRG-PSW
KKGSSMS-SSGKAHQEE-VEYVTMAP---------------------FP------RQEIS
YAALSLAA-LGQEPIYNNTGS-LGTHVPSASLE----EST--QYSSIKRPPVAM-P----
----------------------

------------------------------------------------------------
---------------------------------------------------------FDL
SASGRLLWR--D-------TWNLCL-----------------------------------
-------PGCCS---L-----------T

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 316)

GPG-SVTG------TEGGSLRVQCRYDEGYRG
Y-NKYWCKG---EHD------TACE-SIVQT-HGKEE--EVRSGRVSIRDNGADATMVVT
IRDLREEDAGPYWCKIQTIWILDEL-------SRDPAV-A--VTV--YVSPGKSSLGVGG
------------------------------------------------------------
------------------------------------------------------------
----------------------------------G--NLSS----------------NSV
SLFS--SIYVQILITLKL-----LLLLG------VLCAVV-WVNR---------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

---------------------------------------------MPRKAEEGDGVSG-P
QMRRLQL-------------------------------------------------QLET
HQWDKTMRLPLA-------LLFLCV----PG-----------------------------
---------SLS--

PF07686 // ENSGT00470000042273_0_Domain_0 (195, 318)

-L-----------SGPS-TVMG------TVGGSLSVQCQYEEEYKT
F-TKYWCRQ---PCL-----L-LWN-PTVAT-GRSEE--KMRSGRVSIVDHAEDLTFTVT
LENLTADDAGKYRCGIATILQEEGL----HGFLPDLFF-Q--VQV--SVSPRSL------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--LS--NVHFLLLILLKV-----PLFLM------MLSAVL-WVNRPQWA--IC--G----
-----------------------TQS-----RPDED------NMQPYLSI--DIL-----
---SRDT--ATHTRRGR-TSGSL---------------------------------VPKN
W-----------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
----------------MVIC----------------------------------------
----C--PGSP-------------ALMAVSD-A

PF07686 // ENSGT00470000042273_0_Domain_0 (214, 319)

VSG------PVRGSLTVQCRYEPGWET
Y-NKWWCQG---AE--L----KSCR-ILVQT-DGSER--EARGDRVSIKDNQKLRVFTVT
MEELRWNNADTYWCGIERYGP-------------DLGV-K--VKV--TIDPVTEQCHYSP
GW----------------------------------------------------------
---------------ET----------------FMKSWCPDADLD-------TCTI-FV-
-------ETTG-SEF---------KVN-----------------------------I--L
SINK--K---------KH-----TF-----------SMIT-LGE----------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MRLLRI-L--LLLV----------------------------------------
----I--QGHF---S----------

PF07686 // ENSGT00470000042273_0_Domain_0 (206, 319)

-ISQEA-TVRG------TEGGTLTAYCEYSPGWES
Y-KKWWCRG---KY--W----NSCR-MLVKT-TGSEQ--LVKKGRASIQDNHSRHTITMT
LENLWYDDADIYWCGIERTGS-------------DLGY-K--FSM--VVDPEGKAGSTSS
------------------------------------------------------------
------------------------------------------A-----------------
----------S-GPF-----------SLLSN--------------------------IQT
HSHA--DNSFVLLTSVKG-----SLLGF------LLCTVM-WRQGT---------QR---
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MRLCAG-------LLLLCF-----------------------------------
-------QGCLS---L-----------T

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 343)

GPG-SVSG------YVGGSLRVQCQYSPSYKG
Y-RKYWCRG---PHD------TTCK-TIVET-DGSEK--EKRSGPVSIRDHAANSTITVI
MENLSEDDAGSYWCKIQTSFIWDSW-------SRDPSV-S--VRV--NVFPATT------
TLPA--------------------------------------------------------
--------------TT-----------AIL---PLVNSG---------------------
----------------------------------Q--NLRIST----NVMFIFQLW----
SLLS--SIQFQVLVFLKL-----PLFLS------MLCAIF-WVNRL--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MHLSLL-V--PFLF---W------------------------------------
----I--SGC--------CTA--QDPVT

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 321)

GPA-EVSG------QEQGSLTVQCRYTSGWKD
Y-KKYWCRG---VP--Q----RSCD-ILVET-DTSEQ--LVKKNRVSIRDNQRDFIFTVT
MKDLRMSDAGIYWCGITKNG

ENSGT00470000042273_0_Linker_0_1 (321, 542)

F-------------DPMF-K--VTV--NIDPAIQVPITVP
TM-------P----PITST-------------------------------T---------
---------------TI----------------FTVTTTVKETS-----------M-FP-
-------TLTS-YYS---------D-NGHGGGDSGSGDDGGGDSGGG--KGGVGDGFLDL
R

PF15330 // ENSGT00470000042273_0_Domain_1 (542, 732)

VLL--PVISAVLLLLLL-----VA-----------LLFA-WRMVRRQK--KA--AGPP-
-------------SEQ-----A--QSLEG--DLCYA------NLSLKQPR--TSPG-SSW
KKGSSMS-SSGKDHQEE-VEYVTMAP---------------------FP------REEVS
YAALTLAS-LGQEPTYGNTGCP-ITHVPRAGLEE---EAT--AYSSIRRPLPAATP----
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MWLCPA-L--LLVI----------------------------------------
----L--SGY--------STV--GNPLIG

PF07686 // ENSGT00470000042273_0_Domain_0 (210, 340)

PG-TARG------PERGSLTVQCRYGPGWET
H-RKWWCRG---AR--W----GRCK-MLVET-TGSEQ--EVRKGHVSIRDNQKNHMFTVT
MEGLRRDDADTYWCGIERTGA-------------DHGV-R--VEV--TVDPDTQNSAPER
TTTVASVAFT----SS--------------------------------------------
------------------------------------------------------------
-------------------------------------------------TSTKTTSPLTR
SLLG--STYFLLLVLLEL-----PLILS------MLGAVL-WVNRPWRS--CA--GRPGW
RADE-----NQ-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------LHSIL------VPP---F------------------------------------
----L--PCC--------STA--QDAIT

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 318)

GPS-MVRG------QERGSLTVRCRYKSKWKD
Y-KKYWCQG---AD--W----RTCE-TLVKT-DASEK--LVKKNRVSIRDNQTDLIFTVT
LEDLRISDAGVYWCGID

ENSGT00470000042273_0_Linker_0_1 (318, 621)

RVGY-------------DHMF-K--VNV--NIDPV-------L
TT-------L----PTTST-------------------------------T---------
---------------TM----------------FTESGAVNGTS-----------S-FP-
-------PMTS-LDV---------AVLC-----------G--LVS----PKSSKSGVFEV
SS-----------------------------------------SICRVK--DA--GPLN-
-------------LPS----

PF15330 // ENSGT00470000042273_0_Domain_1 (621, 732)

-VS-QSLEG--DVCYA------NLSLQQPR--PSHG-SSQ
KKGSSMS-SSGKAHQEE-VEYVTMAP---------------------FP------REEIS
YAALTLAA-LGQEPIYNNTGSSLPGAMP--------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MMRLLL----------LWGWIII-------------------------------
-------PGYG--------------AMVG

PF07686 // ENSGT00470000042273_0_Domain_0 (210, 319)

PK-EVSG------PEGSSLSVQCFYEDKHEE
N-SKYWCKV---TGLFF----QRCI-TIITT-E-SGK--EETDGKMSIMDNPQSRTFTVI
MRNLTLKDAGQYQCGISRFGV-------------DEVF-E--VTV--VVFSGLGS-----
-----SVSPNPSLQSL----STRSVHRGAKVWGTRSPE--LSSRPS---ILLWKSE----
---------------------------------KCSPSLSPISSPLYPVPSPMSLCISP-
--VPLSLPSPS-PFP------------IS-HLLLP--LPSPSF---PLPF-FSSLSSVPR
PSIPLIRILAPCIILLLLLV----VVIA------TLLSFFSYFLNW--R--KEDVEIET-
-SR---------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
-----------------------------------------------------------E
SPAGRTMWLLPA-L--LLLI----------------------------------------
----I--PG

PF07686 // ENSGT00470000042273_0_Domain_0 (190, 349)

CF---S-----------MSGPW-SVSG------PRGGSATIQCRYDPGWES
Y-SKWWCRG---ES--W----GSCD-TLLKT-TGSEW--KVQSGRMSIQDDHWRHRFTVT
IEELRASDEDVYWCGIEKAST-------------PSPH-SSHHSL--VGSPKSRVRLPSH
PGSSLSG-----------------------------------------------------
----------------------------------LPSIGSLPCS---------S-P-SP-
-------SFFE-GPT-----------IAPS----------YTIPGGR----------PRW
FLLC--NLHVVLLTVIKV-----PLLGC------LLCTLM-WLSRS---------QGDPK
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MWLSPV-L--LLLI----------------------------------------
----L--LGY--------STA--SGQIT

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 320)

GPV-TVSG------SEQGSLTVTCHYDPYWTT
H-KKWWCRG---AD--W----GSCV-ILVMT-TGSNQ--KVKKDRVSIRDYQKKLTFTVT
MENLRRDDADTYWCGIEKDGP-------------DHRV-K--VEV--TIVS---------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
----------SA-------LLLLLV-----------------------------------
-------PGYFP---L-----------SH

PF07686 // ENSGT00470000042273_0_Domain_0 (210, 318)

PR-TAAG------PVGGSLSVQCRYEKEHRT
L-NKFWSRP---PQI-----F-LCD-KIVET-KGSAG--K-RNGRVSIRDSPANLSFTVT
LENLTEEDAGTYWCGVDTPWLRD--------F-HDPIV-K--VEV--SVFPAGTT-----
----------------------------------------------------TAS-----
---------SPQSSMGTS-V---------P---PT--KLPVHT---------------W-
-------P-----------------------SV-------------TRKDSPE-PSPHPG
SLFS--NVRFLLLVLLEL-----PLLLS------MLGAVL-WVNRPQRS--SR--S----
-----------------------RQN-----WP---------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MQLL-----------LLCGCLVLPASLDLRGAP-ALLLQDPRAFSQEMPGFHPQ
PVDSG--PGYG--------------AVV

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 319)

GPK-EVSG------FEGDTVSLQCSYGEERRT
F-RKYWCRI---GGIFI----SRCS-GRVYA-GGDSQ-----EGRVSVRDRRKELRFTVT
LRNLTLQDAGQYWCGVQRLGF-------------DETF-L--VSL--LVFPG--------
--PCCPSSPSPSFQPL----TTTRLQPKAKAWQTQPPELRIAYP----------------
------------------------------------------------------------
------------------------------ATQLH--ATSTKG---PGPRSSSSSSSRPR
VSIPIARILAPVLILLALLL----A--T------ALAALGSHVLCR-RK--EVPLAKET-
-ERR----------EKVDFA---HSPPGNSWVPEYA------VINLAGT-----SG----
---PPLSPQPSASAYKD-IQLLSQT------------------------------SVEEE
--V-PQD-------PEGDRIPV----PPAPGSGE---EPGLPKLTSV-------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MWLSQA-L--LLLI----------------------------------------
----L--AGY--------SIA---TE

PF07686 // ENSGT00470000042273_0_Domain_0 (207, 335)

ITGPT-TVNG------LEWGSLTVQCAYGSGWET
Y-LKWWCRG---AD--W----NGCN-ILVQT-NGSEQ--EVKKNRVSIRDNQKNRLFTVT
MENLKRDDADSYWCGIQKTGI-------------DLGV-N--VQV--TIKPDTQTPALEW
TTATASLAFT----PA--------------------------------------------
------------------------------------------------------------
-------------------------------------------------ATQKTSSPFTR
SLLS--STHFLFLLLLEL-----PLLLG------MLGAVL-WVNRPQRR--S--------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
-----------------------------------------------------------M
TQLASAVWLPTLLL-----LLLFW------------------------------------
----V--PGCVP---L-----------RGPA-V-KE------TVGESLEVELVSMKERFK
M-NKKWCRE---V-T-----CLLCK-IIVIP-GGS-E--EARNGRVSIRNRD-NLAFTS-
GTYLTLEDAGTYMCAVDIPLID-------------HSF-K--VEL--SVVPGNI----PV
SS----------------------------------------------------------
---------P-----GTT-R---------E---TTVVPTSFST---------------K-
-------GPT---Q-----GSIPEGHHEHYEPQ-G-------------------------
LSLP---------V

PF15330 // ENSGT00470000042273_0_Domain_1 (555, 733)

LLSV-LALLLLLLV------GTSLLA-WRMFQK-RSVKA--DKHPE
MSQN---------LRQ-----AEEQS-----ESQYV------NLQLHT-----LP-----
---LREE--PVPPSQVE-VEYSTLAL---------------------PQ-------EELH
YTSVVFD--SQRQNSHANGDPP------CQSPD----QKT--EYSEIRKPREGLSDPHP-
----------------------

------------------------------------------------------------
-----------------------------------------------------------M
TLREGAWWLPSV-------LLLLQ------------------------------------
----V--PG

PF07686 // ENSGT00470000042273_0_Domain_0 (190, 348)

CVS---L-----------SGPG-YVTG------TVGGALRVQCRYEEEYRD
H-LKYWCKR---PFL-------RWV-KIVVT-KVS----ERRSGRVTIRDNPATLTFIVT
WRNISEDNAGIYQCGIDF-L-------------RDPTI-P--VTV--SVXXXXXXX----
XXXX--------------------------------------------------------
---------XXXXXXXXX-X---------X---XXXX-XXXXXX-----------X----
--------XX---X-----XXXXXXXXXSLLS----------------------------
-SV-----PFLLLVFPKISL------LS------MLSVIL-WVHR----P--R--GDSQS
RENQ---------PQ------G--------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
-----------------------------------------------------------M
TARAWASWRPSA-------LLLLLV-----------------------------------
-------PGCFP---L----------

PF07686 // ENSGT00470000042273_0_Domain_0 (207, 332)

-RGPS-TVDG------PVGGSLSVQCRYEEKHKT
L-NKYWCRP---PRA-----L-QCD-KIVET-QGPAG--E-MNGRVSIRDSPGNLSFTVT
LENLTEEDAGIYWCGVDTPLLQE--------F-HDPYV-Q--VEV--SVFPGGALAQ---
------------------------------------------------------D-----
---------RPQSSMGTS-G---------P---PT--KLPVHT---------------W-
-------P-----------------------SV-------------TRKDNPE-PSPHPG
SLFS--NVRFLLLVLLEL-----PLLLS------MLGAIL-WVNRPQRS--SR--S----
-----------------------RQS-----WPVGE------NQ----------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
----------------MSKTLTGNLDNRRGQLGSPG--L---WNPAGIWICCWLRVKGVE
REGETMWWLSPA-L--LLLG----------------------------------------
----F--PGCF--------------SI

PF07686 // ENSGT00470000042273_0_Domain_0 (208, 348)

QGPA-LVRG------PENGSVTIRCRYSSRWRT
Y-NKWWCRG---AD--W----ITCR-VLIRT-KGSEE--EKKSGRLSIRDNWRDNSLLVT
MEMLTQNDTDTYWCGIEKFGT-------------DRGT-R--VKV--TVYSVGKDSMSSN
-GLSTM------------------------------------------------------
----------------------------------------------------------S-
-------TM------------------------------------------DSSAYMMSS
DLHN--RTHYILLMFVKV-----PVLLI------LAGVVL-WLKGSTQK--VS--EEQW-
-----------------------KHTLCS--NLDSEL--LIKDIAP--------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MWLSQA-L--LLLI----------------------------------------
----L--PGY--------SIA---TEIT

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 318)

GPT-TVNG------SEWGSLTVQCAYGSGWET
Y-LKWWCRG---AD--W----YGCN-TLVKT-NGSEQ--EVRKNRVSIRDNQKNRMFTVT
MENLKRDDADSYWCGIQRTGI-------------DLGV-N--VQV--IIKPDTQTPVPEW
TTATASLAFT----PA--------------------------------------------
------------------------------------------------------------
-------------------------------------------------ATQKTSSPLTR
SLLS--STHFLFLFLLEL-----PLLLG------MLGAIL-WVNRPQRR--S--------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
EMSQGVVGLPVA-------LLLLCI----PG-----------------------------
---------CLP---L-----------ICSS

PF07686 // ENSGT00470000042273_0_Domain_0 (212, 318)

-PVMG------TVGESLSVQCWYEQKYKM
F-KKYWCRQ---PCL-----P-LWH-QVVET-RGSDG--EVRSGRVSITDHSGNLTFTVT
MENLTADDEGKYRCGIATILKEEGF----HGFLPDLFF-Q--VQV--LVSPGESLLS---
------------------------------------------------------------
---------LARGEKESE-L---------L---ST-E-----------------------
------------------------Q---P-RKL-------------AQEQQIK-PTPRVR
SLLG--SVHFLLLVFLKV-----PVFLS------MLGAVL-WVSRPQRA--PW-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MWLSPA-L--LLLI----------------------------------------
----L--PGY--------SIA---AKIT

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 348)

GPT-TVNG------SERGSLTVQCAYGSGWET
Y-LKWWCQG---AD--W----NYCN-ILVKT-NGSEQ--EVKKNRVSIRDNQKNHMFTVT
MENLKRDDADSYWCGTERPGI-------------DLGV-K--VQV--TINPGTQTAVPEW
TTTTTSLAFT----AA--------------------------------------------
------------------------------------------------------------
-------------------------------------------------ATQRTSSPLTR
SPLK--STHFLFLFLLEL-----PLLLS------MLGTVL-WVNRPQRR--S--------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MRLLVL----------LWGCLVL-------------------------------
-------PGYE--------------ALD

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 318)

GPE-EISG------FEGDTVSLKFTYKEELRD
Y-RKYWCRN---VGLFF----SRCA-GTIYS-GEEGQ--ETTEGRVSIRDSRQELSFTVT
LRNLTLKDAGKYWCGVKGV---------------NKHL-L--ITL--VIFPA--------
--S----------------------------------------PGLYPAVTTAKQGKTVA
KATPFPGTSRYG---------------------------HEGNS-------QCTGT-SP-
-----H-AATS-PPA----G-----SSRP-IMHLD--STSAED---ASPA-LSNGSSKPR
LSIPLVRILAPVLVLLSLLG----A--A------GLITFSSHLLRW-RK--EAQLATET-
-QRN----------E-VYLS---HLNALMF------------------------------
---SLSLPWL--------------------------------------------------
------------------------------------------------------------
----------------------

---ERTAPGPGHVQPATPCSSPRLLHSDPLEFKSNVRVAQGAERL----GGSRSETRTQT
PLRRLEPVA---------------------------------------------------
-GWEGAAVLPAA-------LFLLHV-----------------------------------
-------PGCLA---L-----------

PF07686 // ENSGT00470000042273_0_Domain_0 (208, 336)

WGPS-NVTG------TEGGSLSVQCHYEEKFKV
L-NKYWCRR---HLF-----L-QCN-KIVET-EGSDS--EVRKGRVSIRDYPANLTFTMT
VGNLIADDGGQYWCGVETPWLSR----------FDPVV-E--IVV--TVSPASIAKS---
-----------------------------------------------------NP-----
---------G--SPSGTP-N---------F---PT--SMPAPN---------------G-
-------P-----------------------RT-------------TEEEPPA-TSPYPR
SLLS--SVHFLLLVFLEV-----PLLLG------MLSAVL-WVNRPQRG--S--------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
-----------LKL--PVVLVLCTA-----------------------------------
---PCPSAG

PF07686 // ENSGT00470000042273_0_Domain_0 (190, 350)

GRA---V-----------RGPG-TVHG------YLGGSLSVSCSYWHGYKN
N-SKFWCRL---GE--VRR-CDFDG-YIIAT-SESNP--QVQRGRFSIWDNRSQRVFTVT
IQNLKAEDAGTYRCGVRKLF------------FYFGNSDD--VEV--IVTPDPT--PTAS
PSTL--------------------------------------------------------
---------A------TS---PGST--LG------------ST---------------Q-
-------LPP---Q---------QE-------GTQ----------V--TA---SPSATPG
HGLD--IALVVLTPCIAV-V---LFLL-------AVAAGV-LVVLSRKR-KQAFSGAAVE
MDRI---------RGT------PNVGA-D--VLHYA------EIGHPD-----SAD----
ESQPYGNVEALRPSANAATDYTEVKR---------------------PSQNLDK-KNEPT
YAMVRKS--QQEEQLYANMLPA------RQRAA----Q----------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MWLPLA-L--LLLS----------------------------------------
----L--SGSL--------------S

PF07686 // ENSGT00470000042273_0_Domain_0 (207, 345)

IQAPE-FVRA------PERGVVVVQCRYDQGWET
H-EKWWCRG---VI--W----HSCK-ILIQT-RGSEQ--EVKSDRVSIRDSWTDRTFTVT
MKGLRQGDADTYWCGIKKIGT-------------DLGT-Q--VKV--IIDP-------AS
FSSKPFV-----------------------------------------------------
--------------------------------------M-------------------P-
--------P------------------------------------------VNINTGMSS
GSNK--RTYYLLLAFVKV-----PILLI------LAGAVL-WLKES-QR--VP--QE---
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
-----MPLLM-L-Y--PLLF---W------------------------------------
----L--SGY---------SI--ATDISG

PF07686 // ENSGT00470000042273_0_Domain_0 (210, 316)

PM-TVNG------PERGSLMVQCVYNSGWET
Y-LKWWCRG---AT--W----YGCK-ILVKT-TGSEQ--EVKRDRVSIKDNQKNHTFTVT
MEDLMQTDADTYWCG

ENSGT00470000042273_0_Linker_0_1 (316, 542)

IERTGT-------------DLGV-I--VQV--IIDPAST----AA
PT--------------TSA-------------------------------S---------
---------------TT----------------FTAPVTPEETS-----------N-SP-
-------TLTG-HHL---------DK---------------------------RHNLLKL
S

PF15330 // ENSGT00470000042273_0_Domain_1 (542, 732)

VLL--PLIFTILLLLLV-----AA-----------SLLA-WRIMKCQQ--KA--AGMS-
-------------PEQ------VPQPLEG--DLCYA------DLTLQLTT--TSP-----
QKATTKLSFSAQADQVE-VEYVAMAP---------------------FP------KEDIS
YASLTLAA-EDQEPTYCNMGPL-SSHIPSGGPE----DPM--EYSIIRRP----------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MRPLVL----------LWGCLVL-------------------------------
-------PG

PF07686 // ENSGT00470000042273_0_Domain_0 (190, 411)

YE--------------ALEGPK-EVSG------FEGDTVSLQCTYGEELKK
Y-RKYWCRE---SGFLI----SRCS-GTVYS-GEYGQ-----EGRVSVHDNPRQLRFEVT
LRNLTLKDVGQYWCGAKRMGF-------------DKTF-S--VSL--LVFPA--------
------------------------------------------SAGLHLTVTTAKLGKTGA
EVSPFTGTSPSE---------------------------HAGTSP-YAGTSPHPAT----
----------S-PPA----GIS-----RQ-ATRLD--STSTED---TSFV-PIRSSSKTR
VSVPMTRMLAPVLVLLALLL----A--T------GLAALGSYMLQW-RK--KAQLATET-
-QRK----------EKVHLS---HLT----------------------------------
-------------------------------------------------------SKEDE
--ASWQT-------PEGDMTPG----PPLPVSGD---EPDFSKFISV-------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MRLLVL----------IWGCLVL-------------------------------
-------PGYE--------------ALE

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 319)

GPK-EISR------FEGDTVSLRCTYREELRD
H-RKYWCRK---GGLLF----PRCS-GTIYA-GKEGQ--ETTEGRVSIHDNRQELSLIVT
LWNLTLQDAGKYWCGVEKRGP-------------DESL-L--ISL--FVFPG--------
--PCCPPSPSPTFQLL----ATTRLQPKAKTQQTQPPG--LTSPGLYPAGTTAKQGKTGA
EATPFPGTSRYG---------------------------HERTS-------QYAAT-SP-
-----H-AATS-PPA----G-----SSRP-PKQLD--STSAED---ASPA-LSSGSSKPR
VSIPMVRILAPVLVLLSLLS----A--A------GLIAFSSHLLLW-RK--EARQDMET-
-QRN----------EKVYLS---HLT----------------------------------
-------------------------------------------------------TEEEE
--APSQA-------PEGDVISM----PPLHTSEE---ELGFSKFVSV-------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MRPLVL----------LWGCLVF-------------------------------
-------PGYE--------------ALE

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 316)

GPK-AVSG------FEGDTVSLRCTYREELRT
H-RKYWCRQ---GGLLF----SRCA-GTLYV-S-GGQ--ETTAGRVSLSDNPQELALTVT
LRDLSLSDAGKYWCGVDRLGI-------------DESL-L--VSL--VVFTG--------
--PCCPPSPSPSLQPL----ATRSPQPEARPGHTRRPE--WTSAALSPAVTTATQGKTGA
GARPFTGTPR-----------------------------HAGTS-------PYAGT-PP-
-----H-TGTP-PHV----GTSHAGSSPL-AVPLD--STTARD---TSVA-PRSGSSKPR
TSIPMVRILAPVLVLLALLL----A--A------GLIAVGSHVLRG-RK--EAQLAAET-
-QRN----------EKVYLS---HLTP---------------------------------
--------------------------------------------------------GEEE
--APFQD-------PEGSVIPM----PPLHMSEE---ELGFSRFVSV-------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MHLALL-V--PVLF---W------------------------------------
----I--SGC--------STA--QDPIT

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 338)

GPA-TVSS------QERGSLTVQCSYESSWKN
K-KKYWCQG---AV--W----KTCE-ILIKT-DASEQ--LVKKDRMSIRDDQTDFIFTVT
MEDLRISDAGIYWCGIERSGY-------------DPY

ENSGT00470000042273_0_Linker_0_1 (338, 542)

F-K--VNV--NIDPAPQAPTTVL
TT-------L----PITST-----------------------------------------
---------------TM----------------STVSVAVNKTS-----------M-FP-
-------MTSS-RYS------------D---------DRPGGDGDGG--GGDGGGGFLEL
S

PF15330 // ENSGT00470000042273_0_Domain_1 (542, 732)

VLL--PVISGVLLLLLL-----VA-----------SIFA-WRMVRRQK--KA--AGPH-
-------------SEQ-----VPQQSLEG--ELCYA------NLSLQQPR--PSHG-SSR
NKGSSMS-ASGKAHEEE-VEYVTMAP---------------------FP------REEIS
YAALSLVT-LGQEPIYNNTGC----HIPSTSLE----EST--QYSSIRRPPVAL-R----
----------------------

MVRTDPPGCVARGMVKTPCKG------------------TGWEKCTEGKAEA----PSGP
ALGRRGVTRAAPPLPSSSASPLE-------EVEAPRSAA--VERSSQLPVCAP-------
ARPALTMRPLVL----------LWACLVL-------------------------------
-------PGYG--------------TLV

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 335)

GPK-EISG------FVGDTVSLQCTYGEALKT
H-RKYWCRK---IGYLI----ARCS-GTVFS-GEYGQ-----EGRVSVHDSPWELRFKVI
LRNLTLEDEGQYFCGIQRLGL-------------DDSF-S--VSL--HVFPG--------
------------------------------------------------------------
-------------------------------------------------TTPHPAT----
----------S-PPA----GIS-----RP-TTQLD--STSAKD---TSLV-RRSSTAKSG
TSIPMTRILAPVLVLLALLL----A--T------GLAALGSWVLQR-RK--EAQLTAET-
-ERK----------EKLQLS---HSPLESSWVPEYT------AINPAGP-----TG----
---PPASP------NTE-IRCLSQA------------------------------SEEDG
--ACLRD-------PEGDVTPG----PPLPVSGE---GPGLSEFISG-------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
-----SHLSLLV-P--LRFR----------------------------------------
----V--TDT--------PNP--PDPVT

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 318)

GPE-EVRS------HEQGSLTVQCQYASCWKG
Y-RKYWCRG---SG--W----RTCV-ILIET-DASER--LVKENRVSIRDDQTNFIFTVT
MEDLRMSNPDIYWCGIMRVGY-------------DHLF-K--VWV--SIDRG--------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----F--PGS--------------SA

PF07686 // ENSGT00470000042273_0_Domain_0 (207, 345)

ISGPR-AVRG------VEQGSLTVQCQYDPGYEH
Y-VKWWCRG---AA--W----NNCR-FVVKT-TGSEK--EVKAGRVSIRDNQKDRSFTVT
MEELRLDDSDTYWCGIERTGT-------------DLGN-K--VEV--TIDPAVPIAPTTV
PTTP--------------------------------------------------------
----------------P----------------TASTVNTKDNI-----------R-FS-
-------AATG-HHS---------NDRLET---------------------TALHDGLKL
SVLL--PLIFAVLLLLFM-----VA-----------SLVA-WRMAKRPK--KG--KGPCS
RKGDETDINQIP-WE------PVLQPLGS--DICYA------DLNLQQIE--KPSD-SSR
KKASGRAPSSPQAYSGD-GDYANTAE---------------------VS------RDSIT
YAALSLDT-SDEQPTYSNMEHL-NNPPPSRILE----KST--VYSTIRKP----------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MWLPSA-------LLLLW------------------------------------
----V--PGCFS---L-----------GG

PF07686 // ENSGT00470000042273_0_Domain_0 (210, 349)

ST-TVTG------SVGGSLSVQCRYEEEYST
A-KKYWCKR---RFV-----VL-CD-KIVET-KDSER--EARTSRVSITDHPANLTFTVT
MRSLRVEDTGTYWCGVNR-Q---L---------FDLTS-E--FEV--SVSPAST-PVVPM
TITT--------------------------------------------------------
---------A-RTSTVTT-E---------V---PAVPSTALSA---------------V-
-------SAT---G-----GASIQDEPQKSSS----------------------------
PRLP---------LLLSL-LAFLLLLLV------GTSLLS-WRMFQK--QVRA--GEPLQ
LSQG---------PRQ-----AAEQG-----EQHYV------NLELLT-----RP-----
---LREE--PVPPRQVE-VEYSTLV----------------------AP------REELH
YTSVAFD--RQTRDSNAHGIPA------QRPGE----QEH--EYSVIRKK----------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MWQFPA-L--LFLF----------------------------------------
----L--PGC--------CTA--QDPVT

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 321)

GPE-EVSG------QEQGSLTVQCRYDSGWKD
Y-KKYWCRG---AY--W----KSCE-ILVET-DASEQ--LVKENRVSIRDDQTDFIFTVT
MEDLRMSDADIYWCGITKAGT-------------DPMF-K--VNV--NIDPEISTTIMTT
TATVLPSTVL----TSTVL-----------------------------------------
-----------------------------------------------------TST-VL-
-------TPTT-PTTE------SIGT---------------E-----NIGQVTQNSLFIW
SLLS--SISFLLMVFVVV-----PLLLS------MLSAVL-WVNRPQRH--YG--GGEIG
LVET-----HR-----------------S--DALDG----EKHFPGDEK-----------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MRPLVL----------LWSCLVL-------------------------------
-------PGYE--------------ALK

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 349)

GPR-EISG------FEGDSVSLQCTYEKKVRT
H-RKYWCRE---GGFML----SRCS-DIVYS-S-QNQ--EVARGRMSIRDTPRELSMTVT
MRDLTLEDSGKYWCGIDRLGL-------------DESF-E--VSL--TVFPGKRDSPI-P
TGTCCPSSPNPSSPPLTATRS---LQPKAKAWQTRVPE--LTSPGLHPTVVTAKQGKTGV
KAPVFTEAAPLAGSAGTSQVLPGTSPYAGSSPHTATPGSSAGTSP-SPGTSPYAGS-SP-
-----H-TATS-PHA----GSS-----RP-VIWPS--PTTAKD---SKA----SSVSKFS
VSIPMVRMMAPVWVLLSLLL----A--A------GLIAFSSHMLQW-RR--KAWLATET-
-QRN----------EKVHLP---ASLPGNSWVPEDA------MINLAAP-----PE----
---YLGNPKLSAVLSTE-TQHLGQT------------------------------TEEEA
--TPPLN-----TE--EDTMAA----PPLQISAE---GLAFSEFISV-------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MHLALL-V--LVLS---W------------------------------------
----I--SGC--------STA--QDKITG

PF07686 // ENSGT00470000042273_0_Domain_0 (210, 321)

PN-MVSG------HEQGSLTVRCRYASYWKE
S-KKYWCRG---AD--W----KTCE-TLVET-DM-EQ--VVKKDRVSIRDDRTDSVITVT
MRELRISDGGVYWCAIERFG

ENSGT00470000042273_0_Linker_0_1 (321, 542)

S-------------DHKF-K--VNV--NIGPA---PTTAL
TT-------L----PITST-------------------------------T---------
---------------TM----------------FTETVAANT-T-----------M-FS-
-------MKTS-YYS---------DGSSV--------SDNGDSGDDS--SDRGGGNVLSL
S

PF15330 // ENSGT00470000042273_0_Domain_1 (542, 732)

VLL--PVVSAVLLLLLL-----VT-----------SLFA-WRMMRRQK--KA--AGPH-
-------------PEQ-----VS-QSLEG--DLCYA------NLSLQQPR--PS----SQ
KNGSSMT-SSGKAHQEE-VEYVTMAP---------------------FP------REEIS
YAALSLVA-LGQEPIYNNTGSH-VTCLPSSSLE----EST--QYSSIKRPPVAM-P----
----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------

PF07686 // ENSGT00470000042273_0_Domain_0 (204, 344)

SMALRGPE-TVVG------TEGGSLDVHCEYEEEFKG
N-DKYWCRT---PRV-----RL-CQ-KLVMT-AGPAR---GRKGPVSIRDEPAQLSFTVT
LRNLTEDDQGAYWCGIHATLWMEE---------CDPTF-Q--VVV--SVSPAPK-SSTPV
STTL--------------------------------------------------------
---------T-TTLTPTM-E---------H---LSVSSTPLPT---------------E-
-------AVT---P-----SRSSLGNPSQSQP----------------------------
PGXX---------XXXXX-XXXXXXXXXXXXXXXXXXXXX-XXXXAQ--RAQ--------
LSRN---------HSL-----LDEPG-----EPCYA------NLELQT-----WP-----
---SGTA--PEQQRDVE-VEYSTVA----------------------AP------MDEVD
YTSVTFA--LPSQGPEAPSTAL------ERPRE----E-P--EYSVVKKPS---------
----------------------

------------------------------------------------------------
------------------------------------------------------------
--------MLLL-F--SIILAFLQG-----------------------------------
-CSIQ--DSS--------------SA

PF07686 // ENSGT00470000042273_0_Domain_0 (207, 317)

ISGPR-AVTG------VEQGSLTVRCRYDPGYER
Y-VKWWCRG---AD--W----SSCR-FVVKTNHGSEK--EVKQSRVSIKDNWKDRSFTMT
MQKLRLDDSDTYWCGIERVGA-------------DLGD-D--VDV--TIDPGKTIAPTTV
PTTI--------------------------------------------------------
----------------P----------------TTSTVNTKDNI-----------R-SS-
-------AATG-HHS---------KDS---------------------------NDGLGL
SVLL--PLIFAVLLLLFM-----VA-----------SLVA-WRMAKRLK--KA--AGTSP
--------------V------EVLQPPGS--DICYA------DLNLQQIE--KPSG-SSR
KKASERAPSSPQAYSGD-GDYANTAE---------------------VS------RDSIT
YAALSLDT-SDEQPTYSNMEHL-NTRPPSRILE----KST--EYSTVRKP----------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------CLS---L-----------S

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 348)

GPR-TVTG------TVGGSLNVQCQYEATYRS
S-SKYWCRK---VVY-----KL-CE-KVVET-KEPER--EERHGRVSIRDHPAQLAFMVT
MWNLTEEDADTYWCQINKN----L---------LDLSF-Q--VKV--SVFPAFT-PTTPT
GTTV--------------------------------------------------------
---------A-KTWTITT-T---------G---PPESPTTLSA---------------V-
-------SPT---H-----SASFQGDHEQRPR----------------------------
SQLP---------LLLSL-LALLLLLLV------GTSLMA-WGLLQK--QLKA--GESSA
LSQN---------PRQ-----VTERS-----ERCYE------NVELLA-----CP-----
---PRKE----SPRRAE-LESDTVA----------------------AP------REELH
YASVVFD--SQSQGS--NRISV------QRTQE----EEP--EYSVIRKTQ---------
----------------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------------RDGR-VPRLP----CSRAEPPALTR
PHPRV--SASA--------------ALTC

PF07686 // ENSGT00470000042273_0_Domain_0 (210, 316)

PE-EESA------FEGDTVTLRCTYEGALRT
R-PKYWCRE---VGVFI----SRCA-NKIFS-GEDGQ--EVRQGRASILDRPGELALVVT
LRGLTLQDSGKYWCGAQKLGP-------------DDAC-L--VAL--AVLPG--------
------------------------------------------------------------
------------------------------------------------------------
-------------------------SSRP-AVLPD--SSTAGD---PGPV-SSSHSSVPS
VSIPTARLLAPILVILSLLL----A--A------GLIALGAHVLQG-RR--PALWAEDT-
-QRG----------KKLYFP---AAPLEASWVPKDT------VVSLARH-----PN----
---PLTSS--SLGSTME-ICYLNQA------------------------------RGEEE
--ALSQA-------PEAAETPV----Q-CRMSEE----PDLAEFIAV-------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------F--------STA--QYAITG

PF07686 // ENSGT00470000042273_0_Domain_0 (210, 321)

PN-MVSG------HEQGSLTVRCRYDSHWKD
Y-KKFWCRG---AD--W----KTCE-ILVRT-DM-EQ--VVKKDRVSIRDDRTDSVITVT
MRELRKSDAGIYWCTIERFGS-------------DHKF-K--VNV--NIDP---------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------VTW
FVMS--SIYFKILVFLEM-----PLFLS------MLSAVL--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
-------------M--LGFC----------------------------------------
----L--LG

PF07686 // ENSGT00470000042273_0_Domain_0 (190, 348)

HF---S-----------ICQER-TVRG------TEGGTLTVNCGYGRGWES
Y-KKWWCRG---RN--K----NSCR-ILVKT-AGTDQ--LVKKDRASIQDNRSQRSFTVT
LEGLQRDDADTYWCGIERTGE-------------DLGY-K--ISV--IVDPEGKADSTRA
Q-----------------------------------------------------------
------------------------------------------------------------
------------GPP-----------LSLPLSL-------GGDSG---------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
-----------------------------------------------------------R
QPRQQDMWLLPV-L--FLPV----------------------------------------
----V--QG

PF07686 // ENSGT00470000042273_0_Domain_0 (190, 348)

HF---S-----------ICQEG-LVRG------TEGGTLTAYCEYTPGWES
Y-KKWWCRG---KN--W----ISCR-ILVKT-NGTDE--LVKKDRASIQDNSNRRTFTMI
LEKLRRDDADTYWCGIERTGV-------------DPVY-K--LSV--IVDPGRHDSLLCS
G-----A-----------------------------------------------------
----------------------------------LVPP--AEG-----------------
----------S-GLF-----------LCLPKGW-------RRDPLPAPS--------FFP
SLLC--SLHFALLTFVKV-----SLLGV------LPCTVV-WLSCS---------QGDPG
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MWLPWA-------LLLLW------------------------------------
----V--PGCFA---LR------GFALR

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 320)

GPS-TVDG------PVGGSLSVQCRYEEKHKI
F-NKYWCRP---PRV-----LR-CA-KIVET-EGPAG--K-MNGRVSIMDCPQNLSFTVT
LENLTEEDAGTYWCGVDTP

ENSGT00470000042273_0_Linker_0_1 (320, 554)

WHQDL---------YDPYA-Q--VEV--SVFPAST-SMTPT
SITA--------------------------------------------------------
---------A-KTSTITT-V---------F---PPVSSTSLFA---------------V-
-------SAT---H-----STSNWKENEEVVS----------------------------
SQLP---------

PF15330 // ENSGT00470000042273_0_Domain_1 (554, 730)

LLLSL-LALLLLLLM------GASLLA-WRMFWK--RIKA--GEHSE
LSQN---------PKQ-----AAEQS-----ELHYA------NLELLS-----WP-----
---LQEE--PAPPREVQ-VEYSTVA----------------------AP------REELH
YASVVFD--S-----NTNRIAA------QRPRE----KEPDSHYSVIKKT----------
----------------------

------------------------------------------------------------
-----------------------------------------------------------M
IRRGIGLWLPSV-------LLLSR------------------------------------
----V--PGCVP---L-----------R

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 343)

GPS-SVTG------TEGESLSVTCPYEERFKS
T-IKYWCRG---SLI------LLCE-DIVMT-RGS-E--EARNGRVSIRDDPDNLTFTVT
LQSLTLEDTGTYMCGVGTPFPYHP-------FGNKMSF-R--VEV--SVVPGSS----PG
SSIK--------------------------------------------------------
---------I-LEP------------------------TR-ST---------------A-
-------SYI---Q-----PSVTTNETIPAPSP-Q-------------------------
TRLI----VFLYMCLLSF-LKLIFLC-F------LFCAVV-WM---NLHQHWSD------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MWLLPV-L--FLPV----------------------------------------
----V--QGS---------

PF07686 // ENSGT00470000042273_0_Domain_0 (200, 350)

-S---VLVAVPN-AVSG------PARGSLTVQCRYEPGWET
Y-SKWWCRE---VE--S----SKCY-ILVQT-NGSEQ--EVKDDRVSIKDDQKLRTFTVT
MEELRWNDADTYWCGIERSGP-------------NPAA-K--VKV--TVDPGKSMCV---
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
-----------------------------------------------------------M
SKQERLPLLLLLPL----SSILLFL-----------------------------------
---CP--KDCLS--

PF07686 // ENSGT00470000042273_0_Domain_0 (195, 318)

-L-----------SGPS-EVTG------IVGKSLIVQCSYEEQYKT
K-HKYWCKS---SYY------IFCE-NY-------------PDSRVSIRDNQENLTFTIT
IKNITEADTGKYFCGIDGLL-------------LDSKF-P--VTI--IISPASTV-V-PN
RYIY--------------------------------------------------------
---------ISITTSPTN-KITS---------------KN-EI---------------G-
-------------G-----EKTSKEINDL-------------------MQLPR-SGVLDK
SV-----------LLLLI-LGLLIILLV------GALCLA-WKMRQKKAREK------SK
VFLD---------SGQ---------PI-N--ELCYK------NLKLQE-----RP-----
---SNQD--PLIQS--N-PEYNTVID---------------------DQ------DQSVT
YSILNFP--PDNQNIAL---ET------QKDLE----EKT--VYDTIKLT----------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------

PF07686 // ENSGT00470000042273_0_Domain_0 (190, 348)

SLP---L-----------TALH-SVSG------TIGSSLTVRCHYETQYKG
Y-NKYWCRG---PDA------PDCT-KIVET-HGKER--EVRSGRVTIRDHAKSLTFTVT
IEDLSAQDAGPYWCRIQTVWILDIW-------SYDPSV-D--VHV--SVFPATTVPPTTT
I-----------------------------------------------------------
------------------------------------------------------------
----------------------------------L--DLCTEE----EEVQT--HC--PG
SLLS--STPFLLLVFLKV-----PLLLI------MLSAVL-WVNRPLRN--PA--AQ---
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
---------------TSGRWVTRAL-----------------LSTPRLQLGPGS--SGAT
CQGDRTMWLPSA-------LLLLCL-----------------------------------
-------PGCLS--

PF07686 // ENSGT00470000042273_0_Domain_0 (195, 343)

-L-----------TGPG-SVAG------TMGSSLRVRCQYEKAYKG
H-NKYWCRG---KYG------RVCR-KIVET-EGEEK--EKRNGRVSIRDHADNLTFTVT
MENLNMNDAGSYWCRIQTIWILDVL-------SWDPSA-Q--VEV--SVFPAPSTTPGST
ACLA--------------------------------------------------------
--------------VP-----------DTL---QTVSDG---------------------
----------------------------------Q--NLST------KEMLA--HC--LG
SRLS--NIHFLLLVFLKL-----PLFLG------MVGAVL-WVNRPQRH--PG--GR---
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
-----------------------------------------------------------M
TPRSGAMWLPSA-------LLLLQV----PG-----------------------------
---------

PF07686 // ENSGT00470000042273_0_Domain_0 (190, 348)

CLS---L-----------SCPR-RVTG------TVGGSLSVQCRYEKKYTD
H-NKYWCKG---PWL-----P-SLTKKTVET-TESER--EVRSGRVSIRDHPATLTFTVT
LESLTEGDEGTYWCGMDRPWTEE--------P-FVPTF-P--VVV--SVSSVQAPLG---
-----------------------------------------------------ST-----
---------STLGPPSTL-G---------P---PS--SLPVTT---------------G-
------------------------------PSM-------------TSQETPV-ANQHPR
SLLS--SVHFLLLIFLKV-----PLFLS------MLSAVL-WVNRPQRA--TC--E----
-----------------------ETQ----------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
----------------MSKTLTGNLDNRRGQLGSPG--L---WNPAGIWICCWLRVKGVE
REGETMWWLSPA-L--LLLG----------------------------------------
----F--PGCF--------------SI

PF07686 // ENSGT00470000042273_0_Domain_0 (208, 349)

QGPA-LVRG------PDNGSVTIRCRYSSRWRT
Y-NKWWCRG---AD--W----ITCR-VLIRT-KGSEE--EKKSGRLSIRDNWRDNSLLVT
MEMLTQNDTDTYWCGIEKFGT-------------DRGT-R--VKV--TVYSVGKDSMSSN
-GLSTM------------------------------------------------------
----------------------------------------------------------S-
-------TM------------------------------------------DSSAYMMSS
DLHN--RTHYILLMFVKV-----PVLLI------LAGVVL-WLKGSTQK--VS--EEQW-
-----------------------KHTLCS--NLDSEL--LIKDIAP--------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
-----------------------------------------------------------M
TARDWATWLPPA-------LLLLHV-----------------------------------
-------PGGFS---L-----------SCPY

PF07686 // ENSGT00470000042273_0_Domain_0 (212, 345)

-SVTG------TVGGSLSVQCQYEKEFRT
G-NKIWSTY--------------RD-DIVAT-GWSER--EVRNGRVSIKDYPESLTFRVT
LDNLTMEDSGNYWCGIQSRPIDG--------S-HQ-AC-Q--VKV--SVFPDDSSLKSPA
LASWEPNQGD----PSRRI------------------FPVFSSAFLLSRTSTAAP-----
---------SPDSVTGTE-G---------P---PT--FLPAGT---------------R-
-------P-----------------------SS-------------SGQDSPD-PSPHPR
CLLD--RSYFLLLVLLKL-----PLLVG------ALGAVL-WVGGPWGS--LR--A----
-----------------------RQC-----RPSDE------AQ----------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MWQWS--I--V-FY----------------------------------------
----F--PGF--------STA--KDQIT

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 319)

GPS-MVSG------QERGSLTVRCRYDPHWKG
H-KKYWCRG---AD--W----GTCA-TLVQT-DTSEK--LVEKNRVSIRDNQTDFIFVVT
MEDLRTSDASIYWCGIERIGN-------------DPGF-K--VNV--NIDPGKKKN-S--
RMTT--------------------------------------------------------
-----------------------------------------------------TAP-VL-
-------TSTP-STRE------NTGN---------------H--------GETQTNPPTW
SLLS--SIYFLILVFLEL-----PLLLS------MLSAVL-WVSRPQRC--SG--GGEVG
LEKF-----QS-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------C------------------------------------
----F--PGY-------------

PF07686 // ENSGT00470000042273_0_Domain_0 (204, 348)

-STLSGPK-AVSG------PKGGSLTVRCSYGPGWET
Y-YKWWCRG---AV--W----NSCK-ILVKT-TGSEK--EEKKGGISIRDSQKNRTFDVT
MEKLKEGDADVYWCGIERIGT-------------DLGV-Q--VEV--SVGPGQAPTTMW-
---------T----TTTST-------------------------------N---------
---------------TT----------------FTVPATPEETT-----------A-SP-
-------TMTS-QRS---------DLYRVNV-------------YLA--GTVLNSVFLDL
KILI--PLVCAVLLLLLV-----AV-----------SLLA-WSMMKRQK--KG--TKPTW
GQGDACTLVHHPPKPT------SLQPLES--DLCYA------HLTLHHAG--TSLV-SSR
KKASTMSASSAQANQAE-VEYVTMAP---------------------FP------REEIS
YASLPLDT-LNQEPTYTNMGHH-TARIPTRSHE----EPT--EYSSIR------------
----------------------

-----MSQGPS---------FPHFLTNHE---NSTKRLMQEAEKCQEKQKRERERVHG-S
CMKRLQP-------------------------------------------LDAP--PLES
SPWGLAMRLLAA-------LLLLWV----PG-----------------------------
---------SLC---L-----------SG

PF07686 // ENSGT00470000042273_0_Domain_0 (210, 317)

PS-TVSG------AVGGSLSVQCRYKEEYKE
F-DKYWCRQ---PCL-----L-IWH-QAVET-RGANV--EVRSGRVSIVDRPEDLTFTVT
LENLTAQDAGKYRCGVATILQEEGL----LGFLPDPFF-Q--VQV--IVPPASSSNS---
------------------------------------------------------------
---------STGMP----------------------------------------------
---------------------------------------------------EP-LSRQQG
SQLS--SIHFLLLVFLKV-----PLLLG------MLSAVL-WVHRPQGA--IC--G----
-----------------------ETQ-----PA---------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------

PF07686 // ENSGT00470000042273_0_Domain_0 (127, 359)

MYLLLL-F--PLLF---W------------------------------------
----D--PEH--------SCS--SDPIMGPE-EVRG------LERGVLTVQCRYDPGWVT
Y-RKWWCRG---AE--Y----GSCK-ILVKT-NGSAF---GVKERVSIRDYKTNHTFTVT
MKELRREDTDTYWCGIERTGT-------------DHAV-P--VKV--TIEPV------LT
PT-------P----AIAST-------------------------------A---------
---------------NA----------------FTVPDTPENST-----------G-FL-
-------NVTS-QHS---------DG---------------------------SGVSPNL
FILL--PLLFTLLLLLLV-----AA-----------SLLV-WRMVRRQR--KA--AGIS-
-------------PEQ------VLQPPED--NICYA------NLNLKQTG--ASPS-SPR
KRGPTQPSSSAQDDQGE-VEYITMAP---------------------FL------DTDIC
YAALSLDT-SDQDSIYINTQDL-TTPLPSRSQE----ELI--QYSAIRKP----------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MY-LQL-F--CLLF---W------------------------------------
----F--SGF--------SAE--KKRITG

PF07686 // ENSGT00470000042273_0_Domain_0 (210, 349)

PG-TARG------QERGSLTVQCQYSSQWKS
Y-RKWWCRG---AD--W----STCK-MLIET-DGSER--LVKEERLSIRDYQKDLMFNVT
LGDLRRDDADSYWCGIEKFGI-------------DLGD-K--VKV--T

ENSGT00470000042273_0_Linker_0_1 (349, 542)

IVPAPPAVPTAL
ST------------TSVST-------------------------------T---------
---------------NT----------------FTVPVTVEETI-----------S-VL-
-------TSTN-DHF------------------------------------SDGYSVTNL
S

PF15330 // ENSGT00470000042273_0_Domain_1 (542, 732)

ILL--PLVCAVLFLLLV-----AA-----------TLLA-WRMMKQQK--KD--RALAA
QIGDVS-----TGALS------SEQPKED--DLCYA------NLSLHQSG--TSPG-SFW
PKAFNKS-SSAQANEEE-VEYVTMAP---------------------VK------REEIS
YASLCLDA-LNQEPTYSNTG-----HTRSRGRE----GAT--EYTSIRKP----------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MWLLPA-------LLLLCF-----------------------------------
-------SGCLS---L-----------T

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 316)

GPG-SVTG------TMGGSLRVWCQYESTYKG
Y-NKYWCQG---QYD------TSCE-SIVET-KGEEN--VEWNGRVSIRDHPEALAFTVT
MQNLNEDDAGSYWCKIQTVWILDSW-------SHDPSD-L--VRV--YVSPATKTPR-RT
TRPA--------------------------------------------------------
--------------TT-----------PIF---LVVNPG---------------------
----------------------------------R--NLSTR------EVL----TKNSG
FRLS--SPHFLLVVLLKL-----PLLLS------MLGAVF-WVNRPPRA--PA--GR---
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MWQFPA-L--LILF----------------------------------------
----L--PGC--------CTA--QDPVT

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 335)

GPE-EVSG------QEQGSLTVQCRYDSGWKD
Y-KKYWCRG---AY--W----KSCE-ILVET-DASEQ--LVKENRVSIRDDQTDFIFTVT
MEDLRMSDADIYWCGITKSGY-------------DPMF-K--VNV--NIDPEISTTIMTT
TATVLPSTVV----PSTVL-----------------PCTVVPSTVLTSTVLTSTVLP---
-STVLTSTVLPSTVLTST-VLPSTV--RTS---TVLPSTVLPSTV-------RTST-VR-
-------TSTT-PTME------SIGT---------------E-----NIGQVTQNTLFIW
SLLS--SISFLLMVFVVV-----PLLLS------RLCAVH-WVNRPQRH--YG--EVEIG
LVET-----HR-----------------S--DAQDE----EKHFPGDEK-----------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
-----------------------------------------------------------M
VRLASAVWLML--F---------W------------------------------------
----L--PGCVL---L-----------R

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 348)

GPS-SMTG------TVGESLRVQCQYEEKHKA
Y-SKYWCRV---S-R-----LRSCQ-NTVKT-RAS-K--EARNGRVSIRDDPATLTFTVT
LDNLTLEDAGTYMCGITPS------------LGIDSYS-K--VVV--

ENSGT00470000042273_0_Linker_0_1 (348, 555)

SVVPDKH----LV
SRTS--------------------------------------------------------
---------A-----MTT-S---------L---ATSLTTSLAT---------------E-
-------GPT---E-----GSTMKEHLEHSEPT-G-------------------------
LSLP---------V

PF15330 // ENSGT00470000042273_0_Domain_1 (555, 733)

LLSV-LALLLFLLA------GASLLV-WRMFQK-RQVKA--AKYPE
LSQN---------LRQ-----AAEQS-----ECQYV------NLQLHT-----WP-----
---LREE--PEPPSQVE-VEYSTVMF---------------------PK-------EELH
YASVAFD--SQRQGSHANGNSP------CLPQD----QKA--EYSEVRKPREGLSDPHL-
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MWLLPA-------LLLLCF-----------------------------------
-------SGCLS---L-----------T

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 316)

GPD-SVTG------TVGGSLRVWCQYESTYKG
Y-NKYWCRG---QYD------TSCE-SIVET-KGEEK--VERNGRVSIRDHPEALAFTVT
MQNLNEDDAGSYWCKIQTVWILDSW-------SRDPSA-L--VRV--YVSPATR-----T
TRPA--------------------------------------------------------
--------------TT-----------PIF---LVVNPG---------------------
----------------------------------R--NLSTG------EVL----TKNSG
FRLS--SPHFLLVVLLKL-----PLLLS------MLGAVF-WVNRPQRA--PA--GR---
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
-----------------------------------------------------------T
PSRRRAVWLSPP-------LLLLLI-----------------------------------
Q-------GCFC---L----------

PF07686 // ENSGT00470000042273_0_Domain_0 (207, 337)

-SGPS-TVSG------TEGGSLSVQCRYQEELRM
R-AKFWCSH---PCL-----P-AQE--IVKT-KLPEE--EARSGRVSIRDHPANLTFTVT
LENLSIQDAGTYQCGVNEPWKWD--------I----FF-L--VMV--LVSPETAPESG--
------------------------------------------------------C-----
---------SPGQGVGSY-G---------G---PT---IPAMT---------------L-
-------P-----------------------AH-------------TGEKPPE-PSPHPG
SLLG--SVHGLLLVFLKL-----PLLLA------MLAAVL-WVNRPQRG--PG--R----
-----------------------GQT-----PWPWP------CFAVL-------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
-----------------MRIVLVWM-----------------------------------
---LF--PGIWA---V-----------SG

PF07686 // ENSGT00470000042273_0_Domain_0 (210, 349)

PS-QVTA------HWGSSLSVSCSYQQGYKL
H-SKVWCKT---YF--FKI---FCT-YMAQT-DGSEA--AVTQGRVSIRDNHTALAFTVT
MRDVTAKDTGWYSCGAVKSL------------WNNQWH-K--TEV--LVSKGKAE-GARG
WCWR--------------------------------------------------------
---------R------QR--ED------G-------------------------------
------------------------K-------HCT----------E--QNLSLTPW----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------AGGQA---V----------

PF07686 // ENSGT00470000042273_0_Domain_0 (207, 338)

-TGPK-QVTV------EQGSSLAVSCSYKPRYKL
N-SKYWCRK---SS--PGF---CLT-YIIQT-DGSEV--TVTQDRVSIRDNHTANSFTVT
LSSVTLADAGRYSCGVRRKL------------GIKRWH-S--TKV--MSIPASRMRRGRG
SAS---------------------------------------------------------
------------------------------------------------------------
------------------------------------------------PAAGTAP-----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
-----------MRL--LAL-L-AWA-----------------------------------
---LL--PGCGA---V-----------MG

PF07686 // ENSGT00470000042273_0_Domain_0 (210, 343)

PG-EVRG------FPGGSLSVTCTYEPGQEE
H-PKFWCKA---RT--ILLFISCGV-DIIMT-SESDP--KAQKGRYSIRDNYTHQAFTVT
VDGLSKEDEGTFLCGVENTY------------LNDKHA----VKV--IVDTASSRLPSST
CTTT--------------------------------------------------------
---------T------FS-DLTLSV--TG------------YT---------------Q-
-------TVS---Q---------GE-------IVQ----------S--TSNPSTPQ----
-VLN--LVEHVLTPAVIV-V---LFLL-------VVAAGV-LVILSRKK--KALSSTDIE
MDRT---------RRM-----SPTQDA-G--ALNYA------DINL-G-----LGG----
AESPYSNAGAVRPLETPPMEYVEVRQ---------------------SAQPLED-EREAL
YAKVQKP-VPQQEQVYANVPAA------PRPSE----E----LYSTVWGR----------
----------------------

------------------------------------------------------------
------------------------------------------------------------
----LGLLGLFV-I--NTGL---C------------------------------------
----F--PGS--------------SDITGPE-AVRG------PV

PF00047 // ENSGT00470000042273_0_Domain_0 (225, 316)

GGSLTVQCRYGPKWKA
Y-IKWWCRG---AR--W----SGCH-ILIQT-SGSEQ--EVKGDRTSIQDDQKSFTFTVT
MEELRWNDADTYWCGIERTGT-------------DLGV-K--VKV--TIDPAPT---TVS
TTI---------------T-------------------------------T---------
---------------TS----------------TTVSTEPAETK-----------G-PP-
-------TETS-HHS---------RGRIWL--------G----GPNS----SIPTNSLKL
SILI--PLILAVLLLLLV-----MA-----------SLLA-LRRMKRQE--RA--AGTS-
-------------PEQVRESPRVLQPPEG--DLCYA------NLALQSTG--TSHD-PSQ
RKACTKPTSSALDDQRE-VEYVTMAP---------------------FP------KEDIS
YAALSWEL-LNQEPTYCNMNYH-VARVPSRSHE----ESM--EYSSIRRP----------
----------------------

------------------------------------------------------------
----------------MSQKIKGNLDSRSGEPGLSQSL----DSPAG----------SSS
EQESRTMWLPPA-L--LLLS----------------------------------------
----L--TGCF--------------SL

PF07686 // ENSGT00470000042273_0_Domain_0 (208, 320)

QGPE-SVRG------SAGGSVTVQCHYSPRWKT
H-NKWWCRG---AS--W----YVCE-ILVKT-RGSEK--EEKNGRVSIRDNQRAQAFQVT
MEGLRQDDSDTYWCGIQRSGT-------------DQGI-P--VKV--AIDPGKNLLICTT
----RP------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------WC
LEWK--KTHYILLVFVKL-----PILLI------LVGAVL-WLKGS-QR--VP--KEQC-
-----------------------RHPICR--NLNSEL--LTKDMTP--------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MRLCAG-------LLLLCF-----------------------------------
-------QGCLS---L-----------T

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 343)

GPG-SVSG------YVGGSLRVQCQYSPSYKG
Y-MKYWCRG---PHD------TTCK-TIVET-DGSEK--EKRSGPVSIRDHASNSTITVI
MEDLSEDNAGSYWCKIQTSFIWDSW-------SRDPSV-S--VRV--NVFPATT-P----
TLPA--------------------------------------------------------
--------------TT-----------AIL---PLVNSG---------------------
----------------------------------Q--NLRIST----NVMFIFQLW----
SLLS--SIQFQVLVFLKL-----PLFLS------MLCAIF-WVNRL--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MRLCPA-------LLLLCL-----------------------------------
-------RGCLS---L-----------T

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 323)

GPG-SVSG------YVGGTVHVRCQYGKSYKD
H-VKYWCRG---KHD------TDCK-TIVEI-KRNGE--EKKNGRVSIRDHAENFSMTVT
MENLSEDDAGSYWCKIQTFFIWDSW-------SRDPAV-L--VKV--HVFPATT-LM-ET
TLPA--------------------------------------------------------
--------------TT-----------PFL---PLVNTG---------------------
-------------------------------------HLRIST----SEVFLLQLW----
PLLS--SVHFQVLVFLKL-----PLFLS------MLCAVF-WVNRLQ-------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MWLPSA-L--LLLI----------------------------------------
----L--PGCL--------------SLRG

PF07686 // ENSGT00470000042273_0_Domain_0 (210, 349)

PV-SVWG------REWESVSVQCHYDPGWET
H-KKWWCRG---AQ--W----ASCR-ILVQT-QGSER--EESGARVSIMDDQRNHSFTVT
MQELRQDDADTYWCGIENPGA-------------NLGT-Q--IKV--TVAPREAALTIVG
SQVS--------------------------------------------------------
----------------------------------------------------------R-
-------RT------------------------------------------TTSRLAASS
RPHS--RTHYVLLVFLKV-----PFLLG------LVGAVL-WLEER-QR--DP--AAQW-
-----------------------EEPIYA--NLSSEL--LTKDAPV--------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--NKFWCES---PCW-----D-RWN-KVVET-SATHR--EAR

PF07686 // ENSGT00470000042273_0_Domain_0 (283, 344)

RGRVTIRDEPANLTFTVT
LENLTEADAGTYQCGVL-YWSTR--------L-QDLHV-S--VVL--SVS----------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------------P
SLLS--SVHLWLLIFLKV-----PLLLG------MMGAVL-RASWPRRG--PR--R----
-----------------------R------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MWLLPV-L--LLLV----------------------------------------
----I--QGRG---NSLCNYK--

PF07686 // ENSGT00470000042273_0_Domain_0 (204, 352)

EPQKSKER-TVRG------TEGGNLTVNCGYGRGWES
Y-KKWWCRG---DD--W----DSCR-IIVKT-TGSEK--LVKKGRASIQDNHSRHKFTMT
LERLQYDDADTYWCGIEKIGN-------------DIGF-K--FYV--AVDPGRHYSFLYS
G-----A-----------------------------------------------------
----------------------------------LVPP--A-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
-------LTVPQ-L--IRLL----------------------------------------
----G--LCS---------

PF07686 // ENSGT00470000042273_0_Domain_0 (200, 348)

-S---ALVAVSD-AVSG------PARGSLTVQCRYEPGWET
Y-SKWWCRG---AE--W----KDCH-ILVQT-NGSEQ--EVKSDRTSIQDDQKSFTFTVT
MEELRWNDADTYWCGIERTGA-------------DLGV-E--VQV--TIDPGKSM-----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
--------MVQECS--LETRAFLLL-----------------------------------
---CL--PGCFA---M-----------SIPG-ILNG------TVA

PF07686 // ENSGT00470000042273_0_Domain_0 (226, 334)

GTLVVKCMYREGEEG
H-RKFLCRG---PD--RR----RCV-RVIET-ALGAGQE-VRRGRVTLKDSPSEHMFLVV
MKDLEVGDADTYWCGVDK---------------NVPQV-P--VAV--TVFPGNECLPSPF
AWQW--------------------------------------------------------
---------L------KS-GSG-------------------SL---------------W-
-------LRG---G-------VGSSPGPRTA------------------FLGG-EGGKEG
PCVH--AHACVR-AGLRA-C---V------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
-----------------------------------------------------------M
TARAWASWRPSA-------LLLLLV-----------------------------------
-------PGCFP---L-----------R

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 352)

GPS-TVDG------PVGGSLSVQCWYEEKYKT
L-NKYWCRP---LLV-----L-QCD-KIVET-EGPAG--K-MNGRVSIRDSPENLSFTVT
LESLTEEDA------------------------------------------AS-------
------------------------------------------------------------
---------SPQSSMGTS-G---------P---PT--KLPVHT---------------W-
-------P-----------------------SV-------------TRKDSPE-PSPHPG
FLFS--NVRFLLLVLLEL-----PLLLS------MLGAIL-WVNRPQRS--SR--S----
-----------------------RQS-----WPEGE------NQ----------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MWLCPA-------LLLLCL-----------------------------------
-------QGCSS---L-----------T

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 323)

GPG-SVSG------YVGGTVHVQCQYGKSYKD
H-VKYWCRG---KSD------TKCK-TIVEI-KGNGE--VKKSGRVSMRDHAGNFSMTVT
MENLSEDDAGSYWCKIQTFFIWDSW-------SRDPAV-L--VKV--HVLPATT-PM-AT
TLAV--------------------------------------------------------
--------------TT-----------ASL---PLVNTG---------------------
-------------------------------------HLRIST----SESFLLQLW----
PLLS--TIHFQILVLLKL-----PLFLS------MLCAVF-WVNRLQKI--PG--GN---
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
-----------------------------------------------------------M
TARAWASWRPSA-------LLLLLV-----------------------------------
-------PGCFP---L-----------RG

PF07686 // ENSGT00470000042273_0_Domain_0 (210, 319)

PG-TVYG------PVGGSLSVQCHYEEEHKT
L-NKYWCRP---PRV-----L-LCD-KIVET-KKPAG--K-MNGRVSIRDSPENLSFTVT
LENLTEEDAGTYWCGVNTPWLQD--------L-HDPIV-Q--VEV--FVFPAS-------
------------------------------------------------------------
---------SPQSSMGTS-G---------P---PT--KLPVHT---------------W-
-------P-----------------------SV-------------TRKDGPE-PSPHPG
SLFS--NVRLLLLVFLEL-----PLLLS------MLGAVL-WVNRPQRS--SR--S----
-----------------------RQS-----WPEGE------NQ----------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
-----------------------------------------------------------M
IRLASAVWLLV--L-----NVGLC------------------------------------
----F--PGCVP---L-----------R

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 343)

GPR-KVEG------TVGESLSVQCQYEEKYRA
N-NKYWCRV---S-L-----IRYCR-DVVKT-RAS-R--EARNGHVSIRDDPANLTFTVT
LENLIPEDAGTYMCGVDIPF----------INGIDSYF-R--

ENSGT00470000042273_0_Linker_0_1 (343, 555)

VEV--SVVPGNL----AP
------------------------------------------------------------
---------S-----LAP-S---------L---APSLAPSLAT---------------K-
-------GPT---R-----GPTMKEHHEHSKPQ-G-------------------------
LSLP---------V

PF15330 // ENSGT00470000042273_0_Domain_1 (555, 733)

LLSV-LALLLFLLV------GTSLLA-WRMFQQ-RQVKG--LHGW-
KTLG---------LAQ-----AAEPR-----ESQYV------NLQLHA-----WP-----
---LGEE--PAPPSQVE-AEYSMVML---------------------PK-------EDLH
YASVAFD--SQRQGSQANGNSP------CLPQN----QEA--EYSEVRKPRKGLSDPHL-
----------------------

------------------------------------------------------------
-----------------------------------------------------------M
PQLTSAVWLPKILL-----LLLFW------------------------------------
----L--PGCVP---L-----------SG

PF07686 // ENSGT00470000042273_0_Domain_0 (210, 332)

PS-TVTG------AVGASLSVQCQYEEKYKS
N-AKYWCRD---S-L-----L-LCK-QIVET-RPP-K--EARSGRVSIRDHPATLTFTVT
MENLTLEDAGTYKCGVDIPITDY-------S

ENSGT00470000042273_0_Linker_0_1 (332, 555)

LGIDDSF-K--VVV--SVVPNKH----P-
-ETL--------------------------------------------------------
---------L-----VPT-S---------L---ATSLITSLNT---------------E-
-------GPT---Q-----GSVKEHHEHP-VPP-S-------------------------
LSLP---------V

PF15330 // ENSGT00470000042273_0_Domain_1 (555, 733)

LLSV-LALLLFLLV------GTSLLA-WRMFQK-RQFKA--AKHPE
VSQN---------LRQ-----AAEQS-----ESQYV------NLQLHT-----LS-----
---LREE--PAPPRQVE-VEYSTVGF---------------------PQ-------EELH
YASMAFD--SERQDSHTNGNSP------RPPQN----TEA--EYSEVRKPKGRPL-----
----------------------

------------------------------------------------------------
----------------MSKTLRGNLDKQSESAEISR--ALGIPLRFGFAAGCS-SRGAAK
WEGRT-MWLSPA-L--FLLS----------------------------------------
----F--PGCL--------------SI

PF07686 // ENSGT00470000042273_0_Domain_0 (208, 345)

QGPA-LVRG------PEQGSVTVRCRYSSRWQT
Y-KKWWCRG---AS--W----STCR-VLIRS-TGSEK--ETKSGRLSIRDNQKNNSFQVT
MEMLRQNDTDTYWCGIEKFGT-------------DRGT-R--VKV--NVYSVGKDTTSTS
NQ-RPW------------------------------------------------------
----------------------------------------------------------P-
-------TV------------------------------------------DSSTDIVSS
DLQK--RTYYMLLVFLKV-----PALLI------LVGAVL-WLKRSTQK--VP--EEQW-
-----------------------RHTLCS--DLDSEL--LAKDISP--------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
-----------------------------------------------------------M
NPREIRLWLPSA-------LLLSLV-----------------------------------
-SDTH--GGHFP---V-----------R

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 320)

GPS-NVTG------TVGESLSVSCQYEEKLKT
K-NKIWCRLKP---N-----L-VCK-DIVKT-SGSE---EARNGRVTIRDHPDNLTFTVT
LENLTLEDAGTYKCAVDIRFFYDA------YLWIGNSF-K--VEL--FVVP------V--
----------------------------------------------------KGS-----
---------SPGNGMNIP-A---------S---PT--SSPVHT---------------Q-
-------PN----------------------VT-------------TDDTIPA-PSPELR
SLLS--SPHFWILVSLKL-----PLFLS------MLGAVL-WVNRPQRS--SG--G----
-----------------------SSS-----WPCYE------NQ----------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
---GGTMWLPSA-L--LLLI----------------------------------------
----L--PGCL--------------SLRGPV-

PF07686 // ENSGT00470000042273_0_Domain_0 (213, 344)

SVCG------RESESVSVQCHYDSGWET
H-KKWWCRG---AQ--W----ASCR-ILVQT-QGSER--EESGARVSITDDQRNHSFTVT
MQELRQDDTDTYWCGIENPGA-------------NLRT-Q--IKV--TVAPKRGETRGTA
ARERKPP-----------------------------------------------------
--------------------------------------GPGEG------------C-LP-
-------RG------------------------------------------LSAVGHGEG
STHP--RTHYVLLVFLKV-----PFLLG------LVGAVL-WLE----------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MWLSPS-L--LLLI----------------------------------------
----L--PGY--------SIA---AKIT

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 348)

GPT-TVNG------SEQGSLTVQCAYGSGWET
Y-LKWRCQG---AD--W----NYCN-ILVKT-NGSEQ--EVKKNRVSIRDNQKNHVFTVT
MENLKRDDADSYWCGTERPGI-------------DLGV-K--VQV--TINPGTQTAVSEW
TTTTASLAFT----AA--------------------------------------------
------------------------------------------------------------
-------------------------------------------------ATQKTSSPLTR
SPLK--STHFLFLFLLEL-----PLLLS------MLGTVL-WVNRPQRR--S--------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------CSS--VQNPT

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 317)

GPK-LVIG------QEKGSLIVKCHYGSSWKT
Y-TKYWCQG---PD--W----KSCR-TLVTT-N-SEQ--LVKKDRVSIKDNQKSLVFTVT
MENLRRSDAGTYWCGIERTGV-------------DPGF-E--VNV--VIDPGKNSSLMYH
TAVDLLW--P--------------------------------------------------
------------------------------------------------------------
------------PYAR------TVGT---------------P-------------ACTRT
SPLN--SVFFQILVFLEL-----PLLLS------MLSAVL-WVNRPQTC--SE--NQ---
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
---------------------------------------------------------GAR
SW-EGTMWLPGA-L--LLLS----------------------------------------
----L--AGCF--------------SI

PF07686 // ENSGT00470000042273_0_Domain_0 (208, 349)

QGPK-HVQG------REQGSLTVQCHYSPQWTN
Y-QKWWCRG---RY--W----RTCH-ILVQT-RGSEQ--EEKQGRVSIVDDQRDHSFTVT
MEKLQRDDMDTYWCGIKKSGT-------------DLGT-R--VRV--TVYP---------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------THYVLLVFLKV-----PILLV------LVSVIL-WLKGS-QR--TP--QEQE-
------------------------PSVLR--DLNFEL--LTRDLAP--------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
----------IV-L--PMP----WF-----------------------------------
-S--F--TGI--------------RCLTGP

PF07686 // ENSGT00470000042273_0_Domain_0 (211, 353)

ASPVPV------HSRESLTVRCSYQTGFET
H-KKYWCKG---GF--W----KNCD-IVIKT-SGTEG--ETTSGRFSIRDEQTQQTFSVT
MTGVTQEDEDTYFCGVERFWT------------ADDMY-E--IKV--TVLPGKVHIGARG
PH----------------------------------------------------------
------------------------------------------------------------
--------------W----------------------------------------RRARL
GVSS--PLSYNLTF------------------------IL-W------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MWLSQA-L--LLLI----------------------------------------
----L--AGY--------SIA---TEIT

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 343)

GPT-TVNG------LEWGSLTVQCAYGSGWET
Y-LKWWCRG---AD--W----NGCN-ILVRT-NGSEQ--EVKKNRVSIRDNQKNRIFTVT
MENLKRDDADSYWCGIEKTGI-------------DLGV-N--VQV--TIKPDTQTPVLEW
TTATASLAFT----PA--------------------------------------------
------------------------------------------------------------
-------------------------------------------------ATQKTSSPLTR
SLLS--STHFLFLLLLEL-----PLLLG------MLGAVL-WVNRPQRR--S--------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MYL-LL-L--VSFL---W------------------------------------
----M--SGC--------STA--QDEVT

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 338)

GPK-EARG------QEQGSLAVQCHYASSWKT
Y-KKYWCQG---AN--W----SSCR-ILVKT-DETET--LMKTDRVSIRDNKTDFIFTVT
MEDLRRSDADIYWCGIERSGI-------------DHR

ENSGT00470000042273_0_Linker_0_1 (338, 542)

S-K--VNV--IIDPALT---TVS
TT-------F----PTTS--------------------------------T---------
---------------TM----------------FTAPITEKETN-----------V-LP-
-------TMTS-YHS---------D---------------------------GRQGIMEL
S

PF15330 // ENSGT00470000042273_0_Domain_1 (542, 732)

VLL--PVISAVLLLLLV-----VA-----------SLFA-WRMMRQQK--KK--ATRS-
-------------PPE-----QVLQSLEG--DLCYA------NLTLQEPR--TFPG-NSW
EQTTTKP-S--SSSQME-VEYVSMAP---------------------FP------RE-VC
YAAVSLAA-LDQEPTYGNVVS----HVPSSSHE----EST--EYSIIKKPKPVAVP----
----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------PT

PF07686 // ENSGT00470000042273_0_Domain_0 (212, 318)

-TVFA------VVGTSVYVNCTYDQKYEA
N-VKYWCRR---MN--RD-----CP-IIVQT-SGSEK--LEKVERISIRDNHALLQFTVT
MDNLTSMDTGTYNCGVN

ENSGT00470000042273_0_Linker_0_1 (318, 443)

VNG------------GPNQLAPV---DS--ASFYI--------
--SG--------------------------------------------------------
---------Y------FC-DLN

PF07686 // ENSGT00470000042273_0_Domain_1 (443, 670)

GPT--TVF---AVVGTSVYVN---------------C-
-------TYD---Q---------KY-EANVKYWCR----------RMNRDCPIIVQTSGS
EKLE--KVER----------------------------------ISIRD-NHALLQFTVT
MDNL---------TSM-----DTGT---------------------YN-----C------
--------GVN-------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
-------------------------MHRRCKPELRQNF----QSASGIRICHWWQIRWTR
SREGRAMWLSPA-L--LLLS----------------------------------------
----L--SGCF--------------SIR

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 349)

GPV-SVRA------PEKGFVKVRCHYKRGWET
H-VKWWCRG---AR--W----VSCE-ILIQT-TGSEQ--EEKKDLVSIKDSHTDCTFTVT
MEGLRQNDSNIYWCGIQRLGP-------------DLGT-Q--VQL--TVDPGKNFLIYTT
R-----------------------------------------------------------
------------------------------------------------------------
--------P------------------------------------------G----SDHC
VPFP--RNHYMLLVFVKV-----PILLI------LVGAIL-WLKGS-QR--VP--EEPG-
-----------------------DQPIYM--NFS-EL--PTKDMA---------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MWLPWA-------LLLLW------------------------------------
----V--LGCFA---L-----------R

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 335)

GPS-TVDG------PVGGSLSVQCCYEEKHKT
L-NKYWCRP---PRV-----LR-CD-KIVET-KGPAG--K-MNGRVSIRDSPGNLSFTVT
LENLTEEDTGTYWCGVDTPLLQDL---------YDPYV-Q--VKV--SVFPASM-SMTPT
SITA--------------------------------------------------------
---------A-KTSTITT-V---------F---PPVSSTSLFA---------------V-
-------SAT---H-----STSNWEENEEVVS----------------------------
SQLP---------LLLSL-LALLLLLLV------GASLLA-WRMFQK--RIKG--GEHSE
LSQN---------PKQ-----AAEQS-----ELHYA------NLELLS-----WP-----
---LQEE--PAPPREVQ-VEYSTVA----------------------AP------REELH
YASVVFD--S-----NR---AA------QRPRE----KEPDSHYSEIKKT----------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MPLLTL-Y--LLLF---W------------------------------------
----L--SGY---------SI--ATQIT

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 349)

GPT-TVNG------LERGSLTVQCVYRSGWET
Y-LKWWCRG---AI--W----YDCK-ILVKT-TGSEQ--EVKRDRVSIKDNQKNRTFTVT
MEDLMKTDADTYWCGIEKTGN-------------DLGV-T--VQV--T

ENSGT00470000042273_0_Linker_0_1 (349, 542)

IDPAPT----PA
PT--------------TPT-------------------------------S---------
---------------TT----------------FTAPVTQEETS-----------S-SP-
-------TLTG-HHL---------DN---------------------------RHKLLKL
S

PF15330 // ENSGT00470000042273_0_Domain_1 (542, 732)

VLL--PLIFTILLLLSV-----AA-----------SLLA-WRMMKRQQ--KA--AGMS-
-------------PEQ------VLQPLEG--DLCYA------DLTLQLAG--TSP-----
RKATTKLS-SAQVDQVE-VEYVTMAP---------------------LP------KEDIS
YASLTLGA-EDQEPTYCNMGHL-SSHLPGRGPE----EPM--EYSTISRP----------
----------------------

------------------------------------------------------------
------------------------------------------------------------
--MSPGRGLPWA-------LLLLR------------------------------------
----L--PGCLL---L-----------SGPS-I

PF07686 // ENSGT00470000042273_0_Domain_0 (214, 318)

VIG------TVGESLSVRCWYDEEDRT
R-NKYWCRE---SFM-----VL-CD-HIVET-KGSMR--VVRRGRVTIRDHPANLSFTVT
LENLTLQDTGSYQCGVD

ENSGT00470000042273_0_Linker_0_1 (318, 555)

VSW---Q---------KDPTV-D--VIV--SVLPATS-EKP-T
SYII--------------------------------------------------------
---------A-RTSTTTA-K---------V---PAISFTSQRN-----------------
--------TT---H-----TSSSQENQQVVQD----------------------------
SRLP---------V

PF15330 // ENSGT00470000042273_0_Domain_1 (555, 733)

LLSL-LGVLLLLLM------GLSLLT-WKILQK--EVKG--GEHSR
PGRN---------PRQ-----AVEQC-----EPHYA------NLQLHT-----WS-----
---LREE--PATPRQVD-VEYSTVA----------------------TA------EEDLH
YSSVVFD--SQKQNSNANGVFS------QRPQE----EEP--EYSVVKKPKNHLLSPCPP
QSAASVGTNRQLSSQQAVPPMP

------------------------------------------------------------
-----------------------------------------------------------M
IPRVMAVWLPSS-------LLLLQV-----------------------------------
-------PGCVP---L-----------R

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 349)

GPS-SMTG------TVGESLRVQCQYEEKYKA
Y-SKYWCRVSR---L-----R-SCQ-NTVKT-RASK---EARNGRVSIRDDPATLTFTVT
LDNLTLEDADTYMCGITP------------SLGIDSYS-K--VVV--SVVPASAAVT---
-----------------------------------------------------GS-----
---------VPENRTNTL-G---------S---LT--SSLVHT---------------Q-
-------PS----------------------VT-------------TEDTTPG-PSPHPR
SLLS--SIYFQLLVFLEV-----PLLLS------MLSAVL-WVNRPQGC--SG--E----
-----------------------KRH-----CPDYE------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
-----MPLLM-L-Y--PLLF---W------------------------------------
----L--SGY---------SI--ATDISG

PF07686 // ENSGT00470000042273_0_Domain_0 (210, 316)

PM-TVNG------PERGSLMVQCVYNSDWET
Y-LKWWCRG---AT--W----YGCK-ILVKT-TGSEQ--EVKRDRVSIKDNQKNHTFTVT
MEDLMQTDADTYWCG

ENSGT00470000042273_0_Linker_0_1 (316, 542)

IERTGT-------------DLGV-I--VQV--IIDPAST----AA
PT--------------TSA-------------------------------S---------
---------------TT----------------FTAPVTPEETS-----------N-SP-
-------TLTG-HHL---------DK---------------------------RHNLLKL
S

PF15330 // ENSGT00470000042273_0_Domain_1 (542, 732)

VLL--PLIFTILLLLLV-----AA-----------SLLA-WRIMKCQQ--KA--AGMS-
-------------PEQ------VPQPLEG--DLCYA------DLTLQLTR--TSP-----
QKATTKLSFSAQADQVE-VEYVAMAP---------------------FP------KEDIS
YASLTLAA-EDQESPYCNMGPL-SSHIPSGGPE----DPM--EYSIIRRP----------
----------------------

------------------------------------------------------------
-----------------------------------------------------------M
TARAWASWRPSA-------LLLLLV-----------------------------------
-------PGCFP---L-----------R

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 323)

GPS-TVDG------PVGGSLSVQCWYEEKYKT
L-NKYWCRP---LLV-----L-QCD-KIVET-EGPAG--K-MNGRVSIRDSPENLSFTVT
LENLTEEDAGTYWCGVDTPWHQD--------F-HDPIV-Q--VEV--SVFPAS-------
------------------------------------------------------------
---------SPQSSMGTS-G---------P---PT--KLPVHT---------------W-
-------P-----------------------SV-------------TRKDSPE-PSPHPG
SLFS--NVRFLLLVLLEL-----PLLLS------MLGAIL-WVNRPQRS--SR--S----
-----------------------RQS-----WPEGE------NQ----------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MRLLIL----------LWGCLLL-------------------------------
-------PGYE--------------AL

PF07686 // ENSGT00470000042273_0_Domain_0 (208, 319)

QGPE-EISS------FEGDTVSLQCTYREELRD
H-RKYWCRK---SGILF----SRCS-GTIYA-EEEGQ--ETMKSRVSVRDSRQELSLIVT
LWNLTLQDAGKYWCGVEKRGP-------------DESL-L--ISL--FVFPG--------
--PCCPPSPSPTFQPL----ATTCLQPKAKAQQTQPPG--FTSPGLYPAVTTAKQGKTGA
ETPPLPGTSQYG---------------------------HERTS-------QYTGT-SP-
-----H-PATS-PPA----G-----SSRP-PMQLD--STSAED---ASPP-LSSGSSKPR
VSIPMVRILAPVLVLLSLLS----A--A------GLIAFCSHLLLW-RK--EAQQATET-
-QRN----------EKVCLS---HLT----------------------------------
-------------------------------------------------------TEEKE
--APSQA-------PEGDVISM----PPLHTSEE---ELGFSKFVSV-------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
----AVLTLKLI-L--STIL---Y------------------------------------
----Y--RGC--------------LSI

PF07686 // ENSGT00470000042273_0_Domain_0 (208, 321)

HGPK-AVSG------PQKGLLTLDCKYDQGWEF
N-KKWWCRG---AD--W----GSCR-ILIKT-KESEQ--EVKVGRMSIRDNQKSRTFTVT
MVDLREEDADTYWCGIERTGP-------------DLGF-Q--VKV--TIDPVWTTAST--
----------------TTT-------------------------------T---------
---------------TT----------------FTTQATSEKTT-----------G-SP-
-------AMTG-PSA------------RG------------------------SLGRMTL
STLL--PLIFAVLLLLLV-----AA-----------SFLA-WRILKRQK--KA--AGTP-
-------------SEQ------VLQVLEG--DSCYA------NLTLQQSG--TSRA-SSR
KKASTKSP-SVRADQAE-VDYVTMAS---------------------LP------EEEVS
YAALCLDT-SYQEPTYGNTGPF-PAQGPTHHHK----EST--EYSTIRKH----------
----------------------

------------------------------------------------------------
------------------------------------------------------------
-----------RRM--GVRPGWTWL-----------------------------------
---LL--PV

PF07686 // ENSGT00470000042273_0_Domain_0 (190, 350)

CQA---L-----------VVPK-EVSG------REGETLSLHCWYARGYEG
Y-NKYWCRG---AA--RG----SCH-KVVET-AGREV--PRRHGRISITDNHLFCVVLLT
VEKLSTEDAGSYWCGVERA-------------GRDIME-P--VTV--RVRPGAAEGN---
--TS--------------------------------------------------------
---------L------QK-GQE--------------------------------------
---------Q---P-------PS-----------------------------S-PPSLSR
PTLQ--V---L----LPT-V---VLLF-------LLAVA-----------G---------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
-----------------------------------------------------------M
SPWALAVWLPLN-------LLLLWL-----------------------------------
-------PGCCL---L-----------R

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 317)

GPS-RVTG------TQGGSLSLQCWYEEKYKT
Y-NKYWCRS---SSV-----LGRCE-NTVKT-KDSER--EVSRGRMSISDHPENLTFTVT
FKNLSLEDSGSYWCGIHIPWHEG--------P--DDSF-L--VSV--SVLPYEPP-----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MHLLPL-F--CLLLR---------------------------------------
----L--SGS--------------SAIS

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 349)

GPR-AVRG------VEQGSLTVRCQYDRGYEP
Y-VKWWCRG---AG--W----SSCR-FVVKTNLGSEK--EVKQGRVSIKDNWKDRSFTVT
MEKLRLDDSDAYWCGIERTGV-------------DLGD-D--VDV--T

ENSGT00470000042273_0_Linker_0_1 (349, 542)

IDPA----PTTV
PTTI--------------------------------------------------------
----------------P----------------TTSTVNTKDNI-----------R-SS-
-------AVTG-HHS---------KDS---------------------------NDGLGL
S

PF15330 // ENSGT00470000042273_0_Domain_1 (542, 701)

VLL--PLIFAVLLLLFM-----VA-----------SLVA-WRMAKRLK--KA--AGTSP
--------------V------EVLQPPGS--DICYA------DLNLQQIE--KPSG-SSR
KKASERAPSSPQAYSGD-GDYANTADVFRDNIPYTPLTPKTSSLQAEVS------RDSIT
YAALSLDT-SDEQPTYSNMEHL-NTRPPSRILE----KST--EYSTVRKP----------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MWLPPA-L--LLLV----------------------------------------
----L--PGS--------SNA--

PF07686 // ENSGT00470000042273_0_Domain_0 (204, 344)

-YPVTGPA-RVSG------LERGSLSVQCHCEHGWEN
H-SKWWCRG---AD--W----ASCI-ILIQT-TGSEQ--EVKKDRVSIRDDQENRTFTVT
MEALRRGDADTYWCGIERAGT-------------SYGV-H--VEV--TIYPATT-NLPTV
RTITPSLAFT----LE--------------------------------------------
------------------------------------------------------------
-------------------------------------------------TTEKTTSTFTR
SLLS--SMHFLLPVFLKL-----LLLLG------LLSAVL-WVNWPLRA--PR-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MWLLPA-------LLLLCL-----------------------------------
-------SGCLS---L-----------T

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 316)

GPG-SVTG------TAGGSLTVWCQYESMYKG
Y-NKYWCRG---QYD------TSCE-SIVET-KGEEK--LERNGRVSIRDHLEALAFTVT
MQNLNEDDAGSYWCKIQTLWILDSW-------SRDPSA-L--VRV--YVSPAITAPR-RT
THPV--------------------------------------------------------
--------------TP-----------PIF---PVVNPG---------------------
----------------------------------R--NLSTG------EVL----TQNSG
FRLS--SPHFLLMVLLKL-----PLLLS------MLGAVF-WVNRP-WA--PA--RR---
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
-----------------------------------------------------------M
TSRSGAMWLPSA-------LVLLQV----PGVRGSARRRFD---SESKACTWAHESG---
LGASH--TR

PF07686 // ENSGT00470000042273_0_Domain_0 (190, 350)

CLS---L-----------SGPR-RVTG------TVGGSLSVQCRYKKEYTD
H-NKYWCND---PCL-----P-SLRMKIVET-TESER--EVRIGRVSIRDEPANLTFTVT
LERLTEGDEGKYMCGIDTPWAER--------Q-IDLIF-P--VEV--SVSPAPTLKT---
-----------------------------------------------------VT-----
---------STLGPPSTL-G---------P---PS--SLPVTT---------------G-
------------------------------PSM-------------TSQETPD-ASQHPR
SLLS--SVHFLLLTFLKV-----PLFLS------MLSAVL-WVNRPQRA--TC--E----
-----------------------ETQ----------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------LHSIL------VPP---F------------------------------------
----L--PCC--------STA--QDAIT

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 319)

GPS-MVRG------QERGSLTVRCRYKSKWKD
Y-KKYWCQG---AD--W----RTCE-TLVKT-DASEK--LVKKNRVSIRDNQTDLIFTVT
LEDLRISDAGVYWCGIDR

ENSGT00470000042273_0_Linker_0_1 (319, 542)

VGY-------------DHMF-K--VNV--NIDPV-------L
TT-------L----PTTST-------------------------------T---------
---------------TM----------------FTESGAVNGTS-----------S-FP-
-------QRSS-PYS---------TLSD---------DGG--DSD----GGSGGSGLLDL
S

PF15330 // ENSGT00470000042273_0_Domain_1 (542, 732)

VLL--PVISAVLLLLLL-----VA-----------SLFA-WRMVRRQN--KA--AGPH-
-------------SEQ-----VS-QSLEG--DVCYA------NLSLQQPR--PSHG-SSQ
KKGSSMS-SSGKAHQEE-VEYVTMAP---------------------FP------REEIS
YAALTLAA-LGQEPIYNNTGSSLVTHIPSTTFE----EST--QYCSIKRP----------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MWPLLL----------LWGCLVL-------------------------------
-------PGHK--------------AL

PF07686 // ENSGT00470000042273_0_Domain_0 (208, 318)

QGPK-EIRG------FEGGTVTLQCSYSEELKA
H-RKYWCRE---VGFVV----YRCS-STIYA-R-KGQ--ETTQGRVSIHDSPQELVFTVT
LRDLTLQDTGKYWCGVQKVGR-------------DEAV-L--ISL--LVSPG--------
--PCCPPSPSPPFQPL----TTRSLQPKAKVWQTQAPG--LTSPGLYPTITTAKQRKT--
------GTSLYG---------------------------HTGTSP-YAGTSPHAGT-SP-
-----H-AATS-PHA----GTSHAESSYP-TTQLD--SISAKG---THPV-PSSSRSKPR
VSIPMVRMLAPVLVLFTLLL----A--T------GLIALGSRALRW-RK--EAQLASKT-
-QGN----------EKVYLS---HMTI---------------------------------
--------------------------------------------------------EEEE
--ATSPA-------PEGDLIPM----SPLHMCEE---KLGFSKFISV-------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MQLLVL----------LWGCLVL-------------------------------
-------PGLG--------------AL

PF07686 // ENSGT00470000042273_0_Domain_0 (208, 319)

QGPK-EISG------FEGDTVSLQCTYDEEQQE
L-PKYWCRE---AGFLL----SRCS-NTVYA-AQDGQ--ETTVGRVSVRDSPQERVLTVT
LRNLTLQDAGMYWCGAKRLGF-------------HKTF-S--VKL--LVFQG--------
--PCCPLSPTASSQPL----VTWSLQPKAKAWPTQPPDPRTAAP----------------
------------------------------------------------------------
-------------AR----------GSSP-TVQLH--APSAED---AMPA-PSSGSSQLR
VSIPTVRMLAPFLVLLTLLV----A--A------GLITVGSHLLPW-RK--EAQPAAET-
-EKSKG--------TQVCLS---ALAP---------------------------------
--------------------------------------------------------EEET
--APSQA-------PEGHMIPA----PTLRKSEE---ELALSKFISG-------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------C--------STA--QDAIT

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 319)

GPS-MVRG------QERGSLTVRCRYDSSWKD
Y-NKYWCQG---AD--W----RTCE-TLVKT-DASEK--LVKKNRVSIRDDQTDLIFTVT
LEDLRISDAGVYWCGIDRIGY-------------DPNF-E--VNV--NIDP--EVSTV--
IMTT--------------------------------------------------------
-----------------------------------------------------TAP-FL-
-------TSTP-STTE------NIGN---------------H--------GETQTSAPTW
SLLS--SIYFQLLVFLEV-----PLLLS------MLSAAL-WVNRPQRC--SG--GGEAG
LEKV-----QS-----------------S--DAWYR----EEHFYVDRK-----------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
-----------------------------------------------------------M
IRRGIGLWLPSA-------LLLSR------------------------------------
----V--PGCVP---L-----------R

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 345)

GPS-SVTG------TVGESLSVTCPYKEKFKS
T-IKYWCRG---SHV------LLCE-DIVMT-RGS-E--EARNGRVSIRDHPDNLTFTVT
LQSLTLEDAGTYICGVDTPFPYYR-------FRNRESF-R--VEV--SVIPGSS----PG
SSIK--------------------------------------------------------
---------I-LEP------------------------TR-ST---------------A-
-------SYT---Q-----PSVTTNETIPAPSP-Q-------------------------
TR----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
--------------------------------------------------------MLLS
HLSILKTFLFIY-L--YMDL---C------------------------------------
----F--PGC---------ST--AQDLSGLA-V

PF07686 // ENSGT00470000042273_0_Domain_0 (214, 316)

VRG------QEKGFLTVDCRYDSSWRT
Y-RKYWCQG---AR--W----SSCR-ILVTT--DSEQ--LVKKDRVSIKDNQTSLMFTVT
MENLRRSDAGTYWCG

ENSGT00470000042273_0_Linker_0_1 (316, 543)

IERTGV-------------DPGF-E--VNV--IIDPGKTPTTVLT
TLPTT------------TT-------------------------------T---------
---------------AT----------------TTAPILAV-----------------R-
-------SLAH-VH----------SLR------------------------CCRHGSLGL
SA

PF15330 // ENSGT00470000042273_0_Domain_1 (543, 732)

LL--PAVAAVLLLLLA-----LA-----------SLLA-WRMKRRLK--KG--PPSV-
------------------LRPQALQSLDA--DLCYA------NLTLQQPR--TSPD-SSR
KKTATKTCSSGQADQAE-VAYVTMAP---------------------FP------KEEVS
YAALSLNN-LDQEPVYSNTGHL-VTHIPSSSQE----VST--EYSTTP------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MWLLPA-------LLLLCL-----------------------------------
-------SGCLS---L-----------K

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 316)

GPG-SVTG------TAGDSLTVWCQYESMYKG
Y-NKYWCRG---QYD------TSCE-SIVET-KGEEK--VERNGRVSIRDHPEALAFTVT
MQNLNEDDAGSYWCKIQTVWVLDSW-------SRDPSD-L--VRV--YVSPAITTPR-RT
THPA--------------------------------------------------------
--------------TP-----------PIF---LVVNPG---------------------
----------------------------------R--NLSTG------EVL----TQNSG
FRLS--SPHFLLVVLLKL-----PLLLS------MLGAVF-WVNRPQWA--PP--GR---
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------

PF07686 // ENSGT00470000042273_0_Domain_0 (190, 431)

SSA---L-----------WGPS-AVSG------PEGGSLSVQCGYDATFKT
Y-NKWWCRPAQ---------------ILVQT-TGSA---GVKKDRVSIRDNHKNLTFTVT
MEKLREADADVYWCGIQRTGTRCR---------PDDSL-K--AQVTGCLSPTT-------
-----------------------------------------------------VS-----
---------SSVTIRMTT-G---------P---PM--FMPATS---------------R-
-------P-----------------------ST-------------TRQETPG-PGQHSQ
SLLS--SVHFLLLVFLKV-----PLFLI------MLSAAF-WVNRHQRV--PR--T----
-----------------------MLG-----HPNQE------HL----------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MWLLPA-------L-LLCF-----------------------------------
-------SGCLS---L-----------T

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 316)

GPG-SVTG------TVGGSLRVWCQYESTYKG
Y-NKYWCRG---QYD------TSCE-SIVET-KGEEN--VERNGRVSIRDHPEALAFTVT
MQNLNEDDAGSYWCKIQTVWILDSW-------SRDPSA-L--VRV--YVSPATKTPR-RT
TRPA--------------------------------------------------------
--------------PT-----------PIF---LVANPG---------------------
----------------------------------R-------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MWLSPA-L--LLLS----------------------------------------
----L--S--------------------------------------

PF07686 // ENSGT00470000042273_0_Domain_0 (227, 349)

SVKVQCHYKRGWET
H-VKWWCRG---AR--W----VSCE-ILIQT-RGSEQ--EEKKDLVSIKDSHTDCTFTVT
MEGLRQNDSNIYWCGIQRRGP-------------DLGT-Q--VQL--TVDPEGAASAPAN
S-----------------------------------------------------------
------------------------------------------------------------
--------S------------------------------------------VNSNIRVSI
STHK--RNHYMLLVFVKV-----PILLI------LVGAIL-WLKGF-QR--VP--EEPG-
-----------------------DQPIYM--NFS-EL--LTKDMAA--------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------APLVTN-H--YFHE----------------------------------------
----Y--PNFW---S-----I--VEN

PF07686 // ENSGT00470000042273_0_Domain_0 (207, 343)

LWGPP-EVTG------TEGESLTVSCQYNLHWER
N-GKWWCRG---ED--W----KSCK-IIVGT-SGSR----EDSGAVSIKDSPRKQTFTVV
MDNVTARDTDTYWCGIEREGD-------------PLRA-Q--VRV--TISTGKISGMEGS
LSLS--------------------------------------------------------
------------------------------------------------------------
--------VIL-GRS-----------------LD------------------------NS
GKSL--HVDVLLLLFLKV-----PTLLG------MVGAVI-WVNRP---------QRAQT
G--------------V------HGSSKRE--S-----------LQPPGP---------HC
Y-----------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
-----------------------------------------------------------M
TARAWASWRPSA-------LLLLLV-----------------------------------
-------PGCFA---L-----------R

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 323)

GPS-TVDG------PEGGSLSVQCWYEEKYKT
L-NKYWCRP---LRV-----L-LCD-KIVET-EGPAG--K-MNGRVSIRDSPENLSFTVT
LENLTEEDAGTYWCGVDTPLLQD--------F-RDPIV-Q--VEV--SVFPAS-------
------------------------------------------------------------
---------SPQSSMGTS-G---------P---PP--KLPVHT---------------W-
-------P-----------------------SV-------------TRKDSPE-PSPHPG
SLFS--NVRFLLLLLLEL-----PLLLS------MLGAIL-WVNRPRRS--SR--S----
-----------------------RQS-----WPEGE------NQ----------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------QPGLTRCFASSVQLRFVFAAGCR-------
SEGVRTMWLSPA-L--LLLS----------------------------------------
----F--PGYL--------------SI

PF07686 // ENSGT00470000042273_0_Domain_0 (208, 345)

QGPA-SVRG------PEQGSVTVQCRYGPRWKN
Y-NKWWCRG---TT--W----NTCR-ILIQT-TSLEK--EKTIGRLSIRDNQRDN-FQVT
MEMLEQNDTGTYWCGIQKTGI-------------DRGV-R--VTV--TVDPGKNFLICTM
SFRGPW------------------------------------------------------
----------------------------------------------------------P-
-------EG------------------------------------------YG-------
-DTS--LTHYVLLVFVKV-----PALII------LAGAVL-WMKRSQRG---C--GEQW-
-----------------------GQSLCR--TSDSEL--LTKDMAP--------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
-----------------------------------------------------------M
VRLASAVWLML--F---------W------------------------------------
----L--PGCVL---L-----------R

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 349)

GPS-SMTG------TVGESLRVQCQYEEKHKA
Y-SKYWCRV---S-R-----LRSCQ-NTVKT-RAS-K--EARNGRVSIRDDPATLTFTVT
LDNLTLEDAGTYMCGITPS------------LGIDSYS-K--VVV--S

ENSGT00470000042273_0_Linker_0_1 (349, 555)

VVPDKH----LV
SRTS--------------------------------------------------------
---------A-----MTT-S---------L---ATSLTTSLAT---------------E-
-------GPT---E-----GSTMKEHLEHSEPT-G-------------------------
LSLP---------V

PF15330 // ENSGT00470000042273_0_Domain_1 (555, 733)

LLSV-LALLLFLLA------GASLLV-WRMFQK-RQVKG--T--PR
MTLD---------LVQ-----AAEQS-----ECQYV------NLQLHT-----WP-----
---LREE--PEPPSQVE-VEYSTVMF---------------------PK-------EELH
YASVAFD--SQRQGSHANGNSP------CLPQD----QKA--EYSEVRKPREGLSDPHL-
----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------SVE

PF07686 // ENSGT00470000042273_0_Domain_0 (207, 349)

VRSPG-QVSG------LAGGSLVLQCHYDKGWEN
Y-RKWWCRG---AL--W----LSCE-ILVTT-TVS-----QRDKRVSIRDDHGARTITVT
MENLRESDTDTYWCGIERSSD-------------DLGA-H--VRV--KVFPGKIPVMGTS
F-----------------------------------------------------------
-----------------------------------SPPHCCHYAG-------PR-P-GP-
-------WLSL-SPL-----------HA--------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
----------------MSKTLRGNLDKQNESAEISR--ALGIPLRFGFAAGCS-SRGAAK
WEGRT-MWLSPA-L--LLLS----------------------------------------
----F--PGCL--------------SI

PF07686 // ENSGT00470000042273_0_Domain_0 (208, 345)

QGPA-LVRG------PEQGSVTVQCRYSSRWQT
N-KKWWCRG---AS--W----STCR-VLIRS-TGSEK--ETKSGRLSIRDNQKNNSFQVT
MEMLRQNDTDTYWCGIEKFGT-------------DRGT-R--VKV--NVYSVGKDTMSTS
NQ-LPW------------------------------------------------------
----------------------------------------------------------P-
-------TV------------------------------------------DGSTDIVSS
DLQK--RTYYMLLVFVKV-----PALLI------LVGAVL-WLKRSTQK--VP--EEQW-
-----------------------RHTLCS--DLDSEL--LAKDISP--------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
----------------MXLF----------------------------------------
----L--PGC--------CTA--QDPVT

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 335)

GPE-EVSG------QEQGSLTVQCRYDSGWKD
Y-KKYWCRG---VP--Q----RSCA-FLIET-DKSEQ--LVKKNRVSIRDNQRDFIFTVT
MEDLRMSDAGIYWCGITKSGY-------------DPMF-K--VNV--NIDQAQKSSVVTT
TATVLKSIQP--------------------------------------------------
------------------------------------------------------------
-------------SAE------NTGK---------------E--QVTQSKEVTQSRPHTR
SLLS--SIYFLLMVFVEL-----PLLLS------MLSAVL-WVTRPQRC--FG--RGEND
LVKT-----HS-----------------P--VA---------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MRLYAG-------LLLLCF-----------------------------------
-------QGCLS---L-----------T

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 343)

GPG-SVSG------YVGGSLRVQCQYSPSYKG
Y-MKYWCRG---PHD------TTCK-TIVET-DGSEK--EKRSGPVSIRDHAANSTITVI
MEDLSEDDAGSYWCKIQTSFIWDSW-------SRDPSV-S--VRV--NVFPATT-P----
TLPA--------------------------------------------------------
--------------TT-----------AIL---PLVNSG---------------------
----------------------------------Q--NLRIST----NVMFIFQLW----
SLLS--SIQFQVLVFLKL-----PLFLS------MLCAIF-WVNRL--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
-----------------------------------------------------------M
IPRGIRLWLPSA-------LLLSQV-----------------------------------
-------PGCVP---L-----------H

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 318)

GPS-TVTG------TVGESLSVSCQYEEKFKT
K-DKFWCRVSL---K-----V-LCK-DIVKT-SGSE---EARNGRVTIRDHPDNLTFTVI
YESLTLEDADTYMCVVDIPFFDAPLG-------LDKYF-K--IEL--SVVPSEDP--V--
----------------------------------------------------TGS-----
---------SLESGRDIL-E---------S---PT--SSVGHT---------------H-
-------PS----------------------VT-------------TDDTIPA-PCPQPR
SLRS--SLYFWVLVSLKL-----FLFLS------MLGAVL-WVNRPQRC--SG--G----
-----------------------SST-----QPCYE------NQ----------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
----SSPWVVRI---------------------------------------IFTHIT---
LLSTL--GS

PF07686 // ENSGT00470000042273_0_Domain_0 (190, 348)

CLM---L-----------SGPS-TVTG------IVGETLSVQCRYEEKFKE
S-DKFWCRE---PAL-----R-PCY-KIVET-SGSER--EKRRGRVSISDHPAQLSFTVT
MTKLTVEDAGKYWCGIDITWLRDAR------LPFDPTF-Q--VVV--SVSPAEPHPH---
-----------------------------------------------------TS-----
---------TRTAGTSSV-P---------A---PR-SSTPTST-----------------
--------------------------------T-------------TSTTTTD-CPIPSK
SPLR--SVHFLLLIFLKV-----PLFLS------ILSAVL-WVNRPQRG--PR--G----
-----------------------RWS-----QPNYE------NQ----------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------TPALI-------------------------------
-------LGYE--------------ALE

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 319)

GPK-EISG------FEGDTVSLRCTYREELRD
H-RKYWCRK---GGILF----SRCS-GTIYA-GKEGQ--ETTEGRVSIHDSRQELSLIVT
LWNLTLQDAGKYWCGVEKRGP-------------DESL-L--ISL--FVFPG--------
--PCCPPSPSPTFQLL----ATTRLQPKAKTQQTQSPG--LTSPGLYPAGTTAKQGKTGA
EATPFPGTSRYG---------------------------HERTS-------QYAAT-SP-
-----H-AATS-PPA----G-----SSRP-PKQLD--STSAED---ASPA-LSSSSSKPR
VSIPMVRVLAPVLVLLSLLS----A--A------GLIAFSSHLLLW-RK--EARQAMET-
-QRN----------EKVYLS---HLPLENGRDTEDA------VINIAGS-----MG----
---PLTVPEPSPSLFTE-IQYLSQT------------------------------TEKEE
--APSQA-------PKEDVISM----PPLHTSEE---ELGFSKCVSV-------------
----------------------

------------------------------------------------------------
-----------------------------------------------------------M
TARAWASWRPSA-------LLLLLV-----------------------------------
-------PGCFA---L-----------R

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 322)

GPG-TVDG------HVEGSLSVQCHYEEEHKT
L-NKYWCRP---PRV-----L-PCD-KIVET-KGPAG--K-MNGRVSIRDCPANLSFTVT
LENLTEEDAGTYWCGVDTPWLQD--------F-HDPVV-Q--VEV--SMFPAS-------
------------------------------------------------------------
---------SPQSSMGTS-G---------P---PT--KLPVHT---------------W-
-------P-----------------------SV-------------TRKDGPE-PSPHPG
SLFS--NVRFLLLVFLEL-----PLLLS------MLGAVL-WVNRPQRS--SR--S----
-----------------------RQS-----WPESE------NQ----------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MYLLLF-F--PLFF---W------------------------------------
----F--SGF--------SAA--QKDIT

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 348)

GPN-AVSG------QERGSLTVQCRYTSKWKT
S-RKWWCRG---AA--W----SSCK-IQIQT-DGSEK--EQKKERLSIRDYQKELMFRVT
LEDLRRDDADNYWCGIERFGT-------------DPGL-K--VKV--

ENSGT00470000042273_0_Linker_0_1 (348, 542)

TVVPAPTTVPTTV
STTTTTTTST----TSVST-------------------------------M---------
---------------NT----------------FTAPVTAEENI-----------S-LL-
-------SPTI-YHF------------------------------------SGRYGITNL
S

PF15330 // ENSGT00470000042273_0_Domain_1 (542, 732)

ILL--PLIFAVLLLLLV-----VA-----------SLLA-WRMRKQQK--KA--A----
-------------ALS------SEQPVEG--DICYA------NLSLHQSG--TFPG-SSQ
QKASTKS-SSAQADQGE-VEYVTMAP---------------------SW------RQEIS
YASLCLDI-LNQEPTYSNTG-----HAPRRGCE----DST--EYTSIRRP----------
----------------------

------------------------------------------------------------
---------------------LTQA-----------------VLTPGFQPGPGF--SGDT
SQGDRTMWLSPA-------LLLLCL-----------------------------------
-------PG

PF07686 // ENSGT00470000042273_0_Domain_0 (190, 348)

CLC---M-----------KSPS-SVMG------TMGGSLRVWCQYEKAYKG
Y-NK-WCRG---KYD------TSRD-VIVET-KGEEK--EERNGRVSIRDYADDLTFTVT
MENLNANDAGS-WCRIQRVWILDVL-------SYDPSV-Q--VKV--SVFP---------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MPLPWA-------LLLLFL----PG-----------------------------
---------CVL---A-----------RNFT-

PF07686 // ENSGT00470000042273_0_Domain_0 (213, 319)

EVKG------IVGEPLSVQCPYKEEYKM
Y-GKYWCRG---NFW-----V-SCS-IIIKT-ESKEG--EVKSGRVAISDSHRNLTFTVT
MENLTADDAGSYACGINKGLIIS-------------WF-R--VSI--S--QGKCLLL---
------------------------------------------------------------
---------PA------P-G---------V---LN-L-----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------EWVTPY-L--Y-LN----------------------------------------
----F--TCY--------STS--SNPLTGPG-AA

PF07686 // ENSGT00470000042273_0_Domain_0 (215, 317)

RG------RERGSLTVQCRYEPGLER
H-RKWWCRG---AH--W----RSCR-ILVMT-TGSEQ--EVKKDRVSIRDSHKNHTFTVT
MEELRRDDADTYWCGIERTGI-------------DFAV-P--VEV--TIAPGKRV--RGR
TTMAASVAFT----PS--------------------------------------------
------------------------------------------------------------
-------------------------------------------------TSMKTTSSVTR
SLLG--STYFLLLVLLEL-----PLILS------MLGVVL-WVNRPWRG--S--------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MYLLLS-F--LFLF---R------------------------------------
----L--AGS--------------AD

PF07686 // ENSGT00470000042273_0_Domain_0 (207, 319)

ITGPA-EVRG------PVGGRLAVHCRYEPWWKI
Y-RKWWCRG---AV--W----SSCR-ILVRT-DGSEQ--EAKRDQVSIKDDWKSQMFTVT
MEKLRWNDTDAYWCGIERTGV-------------DSGV-V--VKV--VIDPATTTVPTS-
------------------T-------------------------------I---------
---------------PS----------------TTMSTGTAETA-----------S----
-------------------------------------------SY----QSSDSSNSLKL
SILI--PLTVAVLLLLLV-----AA-----------SFLA-LRKMRQPN--EA--AGVS-
-------------PEQVVQPPE----REA--DICYA------NLALQSTS--TSHK-SSQ
KKGCTKPSSSAQDDQPE-VEYVTMGP---------------------LQ------KEEIP
YADLSWEL-LNQDATYCNMSFH-VAHVPSRSHE----ESM--EYSSIRRSKPGLQAPLAH
PT--------------------

------------------------------------------------------------
------------------------------------------------------------
----------------MHWIRCGGL-----------------------------------
---CF--SGYFT---L-----------SIPR-

PF07686 // ENSGT00470000042273_0_Domain_0 (213, 337)

ILKG------TTGGTLVMECRYNVGEEG
H-RKFWCRG---PN--WT----DCV-RVIET-EQMAGQE-VRRGRVTLRDNPREHLFHVI
TEDLEEGDADTYWCGVDRA-------------TSVPQA-P--VAV--TVFPGSATVSMMT
TETL--------------------------------------------------------
---------A------SM-GAP-------------------AL-----------------
--------TS---H-------MA-SPG-----------------------------LPAW
PFLF--FASFLFLVLLKV-S---LFLS-------FSYAAI-WLAWLQRH-L---------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
----------------ARKTPTGNLDKQKGSAGLSG--ALHIQLGFGFAAGCPSR-----
--GGRTMWLTPA-L--LLLS----------------------------------------
----F--PGCF--------------AI

PF07686 // ENSGT00470000042273_0_Domain_0 (208, 348)

QGPA-WVRG------PEKGSVTIQCRYSSRWQA
Y-NKWWCRG---AN--W----KTCR-VLIRT-TGSEK--ERKSGRLSIRDNWRENTLLVT
MEMLRQNDTDTYWCGIEKFGT-------------DRGT-R--VKV--TVYP-GKDTMSSQ
L----D------------------------------------------------------
----------------------------------------------------------S-
-------SM------------------------------------------DSNTHVISS
DLYK--RTHYILLAFLKV-----PALLI------LTGVVL-WLKRSTRK--VP--EEQR-
-----------------------RHTLSS--NSDSEI--LDKDIAP--------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------

PF07686 // ENSGT00470000042273_0_Domain_0 (205, 348)

YSTVGPS-AVSG------PKGGSLTVWCSYDPGWEH
F-YKWWCRG---AH--W----NSCR-ILVKT-TGSEK--EVKNDHVSIRDSHKERTFTVT
MEKLREEDAGFYWCGIEKIGT-------------DLGV-Q--VEV--SIDPAQATS----
------------------------------------------------------------
----------------------------------------EETT-----------G-FP-
-------AMTS-QHS------------------------------------YVRPKIMEL
QILI--PLVITLLLLLLM-----AV-----------SLLA-WRMVTQKK--KA--AET--
------------SSEQ------MIQTLDG--GICYA------HLTLQHSG--TSPD-SSW
IKTSTKSASSVQANQAE-VEYVTMAP---------------------IQ------RKDIL
YASLTLDT-SNHEPTYSNMSQL-MVHIPPGNYE----EPT--EYSCIMRS----------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MWLPWT-------LLLLW------------------------------------
----A--PGCFA---L-----------S

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 324)

GPR-TVAG------PLGGSLSVQCGYEEEHRT
L-NKYWCRV---RWT-----IG-CA-KIVET-KGSAG--KLRNGRVSIRDHPANLSFTVT
LENLTEDDAGAYWCGVDTPLLHN

ENSGT00470000042273_0_Linker_0_1 (324, 554)

F---------HDRFI-Q--VEV--SVFPAST-SMTPT
SVTV--------------------------------------------------------
---------A-RTSTITT-A---------F---PPVPSTTLLT---------------V-
-------SAT---H-----STSIQEDNEEVMN----------------------------
LQLP---------

PF15330 // ENSGT00470000042273_0_Domain_1 (554, 733)

LLLSL-LALLLLLLV------GASLLV-WRMFQK--RVKA--GEHSE
LSQS---------HRQ-----AAEES-----EQYYA------NLELLT-----WP-----
---LQEK--PTPSPQVE-VEYSTVA----------------------AP------REELH
YASVVFD--SQSQNSNANRIAA------QRPRE----EEPDSNYSVIRKT----------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MWLLPA-------LLLLCF-----------------------------------
-------SGCLS---L-----------MG

PF07686 // ENSGT00470000042273_0_Domain_0 (210, 318)

PG-SVTG------TVGGSLTVWCQYESTYKG
Y-NKYWCRG---QYD------TSCE-SVVET-KGEEK--VERNGRVSIRDHPEALAFTVT
MQNLNEDDAGSYWCKIQTVWILDSW-------SRDPSD-L--VRV--YVSPATKTPR-RT
TRPA--------------------------------------------------------
--------------TT-----------PIF---LMVNSG---------------------
----------------------------------R--NLSTG------EVL----TKNSG
FRLS--SPHFLLVVLLKL-----PLLLS------MLGAVF-WVNRPQRA--PA--GR---
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
----------------------------------------------------PW--VDQ-
----------RS-G--WGLC----------------------------------------
----V--SGCF---SLT---D--SKEV

PF07686 // ENSGT00470000042273_0_Domain_0 (208, 321)

RSPG-CVSG------PDGGSFTMQCHYDHGWET
Y-VKWWCRG---AN--W----NSCR-IMVRT-TGSES--EQKNGSVSIRDNRQDCMITVT
MENLRAGDADTYWCGIEKAGT-------------DLGA-H--VVV--TINTV-FP-----
------------------------------------------------------------
--------------------------------------FCQLNNS-------TS----P-
-------SLHL-HQL-----------INSPH--KGSGRNQP-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MWQFPA-L--LILF----------------------------------------
----L--PGC--------CTA--QDPVT

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 321)

GPE-EVSG------QEQGSLTVQCRYDSGWKD
Y-KKYWCRG---AY--W----KSCE-ILVET-DASEQ--LVKENRVSIRDDQTDFIFTVT
MEDLRMSDADIYWCGITKAGT-------------DPMF-K--VNV--NIDPEISTTIMTT
TATVLPSTVL----TSTVL-----------------------------------------
-----------------------------------------------------TST-VL-
-------TPTT-PTTE------SIGT---------------E-----NIGQVTQNSLFIW
SLLS--SISFLLMVFVVV-----PLLLS------MLSAVL-WVNRPQRH--YG--GGEIG
LVET-----HR-----------------S--DALDG----EKHFPGDEK-----------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MWLSPA-L--LLLS----------------------------------------
----L-

PF07686 // ENSGT00470000042273_0_Domain_0 (187, 349)

-S-----------------------------------EKGFVKVRCHYKRGWET
H-VKWWCRG---AH--W----VSCK-ILIQT-RGSEQ--EEKKDHVSIKDSHTDCTFTVT
MEGLRQNDSDIYWCGIQRLGP-------------DLGI-P--VQL--TVDPEGAASAPAS
P-----------------------------------------------------------
------------------------------------------------------------
--------S------------------------------------------VNSNIRVSI
SSHK--RNHYMLLVFVKV-----PILLI------LVGAIL-WLKGS-QR--VP--EEPG-
-----------------------NQPIYM--NFS-EL--LIKDMDA--------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MWLPPA-L--LLLS----------------------------------------
----L--SGCF--------------SI

PF07686 // ENSGT00470000042273_0_Domain_0 (208, 348)

QGPE-SVRA------PEQGSLTVQCHYKQGWET
Y-IKWWCRG---VR--W----DTCK-ILIET-RGSEQ--GEKSDRVSIKDNQKDRTFTVT
MEGLRRDDADVYWCGIERRGP-------------DLGT-Q--VKV--IVDPEGAASTTAS
S-----------------------------------------------------------
------------------------------------------------------------
--------P------------------------------------------TNSNMAVFI
GSHK--RNHYMLLVFVKV-----PILLI------LVTAIL-WLKGS-QR--VP--EEPG-
-----------------------EQPIYM--NFS-EP--LTKDMAT--------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
-----------------------------------------------------------M
TQLASALWRPTL-L-----LLLFW------------------------------------
----L--PDCVP---L-----------H

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 316)

GPS-EVTG------TVGESLSVRCQYEEKYKS
N-NKYWCRG---S-L-----LLSCK-EIVRT-RAS-K--EAGNGRVSIRDHPANLTFTVT
LENLTLEDAGTYKCAVDRRLFDDSLGIR-ASLGIDDSF-K--VVV--SVVPEPA----P-
-RTP--------------------------------------------------------
---------T-----MPT-S---------L---TTSLTTSLTT---------------E-
-------CST---Q-----GSIMKGHDEDPESK-G-------------------------
ALVPDLEVATPAMWFPQE-KALLLFLLV------GTSLLA-WRMFRK-HQIKA--DKHPE
LSQN---------LRQ-----AAEES-----ESQYV------NLQLHT-----LP-----
---LREE--PALPSQVE-VEYSTVTF---------------------PQ-------KELH
YTSVVFD--SQSQDSSANGTSP------WSSQN----QEA--EYSEVRKPREGLAHSHL-
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MRLLIL----------LWGYLVL-------------------------------
-------PGHK--------------ALK

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 319)

GPK-EISG------FEGDTVTLQCTYEKTLKE
H-RKYWCQQ---GGILV----SRCS-GIIYT-R-EDQ--EVTEGRVSIRDSPQDLLVTVT
MRGLTLKDAGKYWCGVDRVGF-------------DEAF-E--VSL--IVFPGKGDSPS-T
TGA----SPFPSFQFLIATTY---LQPSAKAWQTQPPE--LTSPDL-PTVTTAKQGKTGV
EAPVFTRVLPTW---------------------------STGTSP-PPGTSPHAGS-SP-
-----H-TVTS-PHS----GSS-----RP-IIWLP--PISPKG---SSDV-TGSSVSNPS
VSIPMVRMLAPVLVLLSLLL----A--A------GLIAFSSHMLRW-RN--KAWLATET-
-QRN----------EKIYLP---TSKLGNGWVSEDA------RINLVAS-----PG----
---PLGSPKLSAGPFAE-IQYRSQT------------------------------TEEEA
--APSQD--------SEDDMVA----TPPLMSSE---ELGFSEFISV-------------
----------------------

------------------------------------------------------------
MIP--R------------------------------------------------------
---GIGLWLPSA-------LL---------------------------------------
-LSGV--PGCFP---L-----------R

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 325)

GPS-SVTG------TVGESLSVTCQYEERFKM
N-KKHWCRGSH---V-----L-LCE-DIVMT-RGSE---EARNGRVSIRDHPDNLTFTVT
LQSLTLEDAGTYMCGVGTPFPYHRF-------WNKESF-R--VEV--SVI----------
----------------------------------------------------PGS-----
---------SLWSSTTVP-E---------T---IR--SSLVHT---------------Q-
-------PS----------------------VT-------------TEDTIPA-PSARPR
SLLS--SLYFWVLVFLEL-----PLFLC------MISAVL-WVNRPR-C--SG--R----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
--IRMETW-----------DVGLC------------------------------------
----L--PG

PF07686 // ENSGT00470000042273_0_Domain_0 (190, 344)

CQS---L-----------MGPG-TVNG------ITGGPVSMYCLYEKVYKE
Y-NKYWCQG---QYD------TTCD-IIMET-KGEEK--EERNGYVTIRDRADNLALLVT
MENLNADD-TVYWCRIQTVWILDV-------LSHGPLV-Q--AKV--SVSPGKT----PL
VYIT--------------------------------------------------------
---------L--L---C---------------------FYLT------------------
--------------------KTTQDIRQE-P-----------------------------
-SIS-----F------------LLYL----------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------TWLPPA-------LLLLW------------------------------------
----V--PG

PF07686 // ENSGT00470000042273_0_Domain_0 (190, 348)

CLS---L-----------WGPS-RVTG------VVGGSLSVECRYTEQYKD
N-SKYWCKA---PCL-----LP-WK--IVET-KEPER--EVMQGHVSIRDHPANLTFTVT
LESLREDQAGKYVCGRSH--------------FRDPTV-Q--VVV--SVFPASV-PP-PT
AV-A--------------------------------------------------------
---------K--TSTITI-S---------I---STMSFTALAM---------------A-
-------SPS---Y-----SANNEEE----------------------------------
---------------AAG-VGLLLLLLG------GISLLA-WRMVQR--RIKS--GENPE
PPQN---------PSQ-----AAELS-----EPCYE------NLELPM-----WP-----
---LLEQ--PVRPTQEE-VEYSNLG----------------------LP------RENLH
YTSVVFD--SRSQDSKTDGIPS------QKPQT----QQP--VYSVVKKT----------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------CLS---L-----------TGPS-SVTG------STGGSLRV

PF07686 // ENSGT00470000042273_0_Domain_0 (231, 316)

WCQYER----
------------QYN------TSCE-SIVET-KGEEK--VERNGRVSIRDHPEALAFTVT
MQNLNEDDAGSYWCEIQTVWILDSW-------SRDPSA-L--VRV--YVSPATTTPR-RT
TRPA--------------------------------------------------------
--------------TP-----------PIF---LVVKPG---------------------
----------------------------------T------G------EVL----TQNS-
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
--MRENTKKTWT-S---RKWMTQAL-----------------LHILGFQLGPRF--AEDG
SQGDRTMWLLPA-------LLLLCF-----------------------------------
-------SGCLS---L-----------T

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 316)

GPD-SVTG------TVGGSLRVWCQYESTYKG
Y-NKYWCRG---QYD------TSCE-SIVET-KGEEK--VERNGHVSIRDHPEALAFTVT
MQNLNEDDAGSYWCKIQTVWILDSW-------SRDPSA-L--VRV--YVSSATKTPR-TT
TRPA--------------------------------------------------------
--------------TT-----------PIF---LVVNPG---------------------
----------------------------------R--NLSTG------EVL----TKNSG
FRLS--SLHFLLVVLLKL-----PLLLS------MLGAIF-WVNRPQRA--PA--GR---
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
-----------------------------------------------------------M
TPRGRAGWLPSA-------LLLLQL----PASRRVQGMKQGPASGIRLTQAHLMESQ---
TRLCF--PGCLS--

PF07686 // ENSGT00470000042273_0_Domain_0 (195, 318)

-L-----------SGPR-RVTG------IVGRSLSVECQYQEEFIN
N-TKYWCKP---PCV-----L-SWR--MVET-TESER--EVRRGRVSIRDHPASLTFTVT
LENLREEDAGTYWCGIDVLS------------TFDPIF-E--VEV--SVITAPATAS---
-----------------------------------------------------GP-----
---------E--RPTGSP-G---------A---PT--TLSVPT---------------W-
-------S-----------------------TA-------------SAQETPD-PGQPPR
PLLG--RAHFLLLVFLKV-----PLLLG------MLGAVL-WVHRPLRS--SA--D----
-----------------------RQR-----QSIYE------NQ----------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
-----MPLLM-L-Y--PLLF---W------------------------------------
----L--SGY---------SI--ATDISG

PF07686 // ENSGT00470000042273_0_Domain_0 (210, 319)

PM-TVNG------PERGSLMVQCVYNSGWET
Y-LKWWCRG---AT--W----YGCK-ILVKT-TGSEQ--EVKRDRVSIKDNQKNHTFTVT
MEDLMQTDADTYWCGIER

ENSGT00470000042273_0_Linker_0_1 (319, 542)

TGT-------------DLGV-T--VQV--IIDPAST----AA
PT--------------TST-------------------------------S---------
---------------TT----------------FTAPVTPEETS-----------N-SP-
-------TLTG-HHL---------DK---------------------------RHNLLKL
S

PF15330 // ENSGT00470000042273_0_Domain_1 (542, 732)

VLL--PLIFTILLLLLV-----AA-----------SLLA-WRIMKCQQ--KA--AGMS-
-------------PEQ------VPQPLEG--DLCYA------DLTLQLTR--TSP-----
QKATTKLSFSAQADQVE-VEYVAMAP---------------------FP------KEDIS
YASLTLAA-EDQEPTYCNMGPL-SSHIPSGGPE----DPM--EYSIIRRP----------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MWLGPG-------LLLLCL-----------------------------------
-------RGCFS---L-----------T

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 323)

GPG-SVSG------YVGGSLHVQCQYGESYKD
H-VKYWCRG---PHD------TECE-TLVEI-KGNGE--EKKNGRVSIRDHAENFTVTVT
MEDLSLDDAGSYWCKIQTFFIWDSW-------SRDPAV-L--VKV--HVFPAPT-TV-ET
TLPA--------------------------------------------------------
--------------TT-----------PIL---PLVNAG---------------------
-------------------------------------YLRVSF----IEVFLLQVW----
SLLS--SIHFQVLVFLKL-----PLLLS------MLCAVF-WVNRLQ-------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
--------------------------LRRCELRPRLAS-------PGI----WACCSVGG
TRSGRTMWLSPA-L--LLLS----------------------------------------
----L--PG

PF07686 // ENSGT00470000042273_0_Domain_0 (190, 348)

CF--------------SIQGPK-SVRG------PEQGSVTLQCHYDAEWEN
Y-RKWWCRG---AN--W----GSCN-ILIRT-NQSSK--AGKRGRVSIRDYPEKLSFAVT
MENLRRDDADTYWCGIERVGT-------------DLGY-R--VKV--TVDP---------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-PFI--RTHYVLLIFVKF-----PILLI------LLGAIL-WLKES-QR--Q--------
-------------------------AVYA--NLS--------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MWLSQA-L--LLLI----------------------------------------
----L--AGY--------SIA---TEIT

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 321)

GPT-TVNG------LEWGSLTVQCAYGSGWET
Y-LKWWCRG---AD--W----NGCN-ILVRT-NGSEQ--EVKKNRVSIRDNQKNRIFTVT
MENLKRDDADSYWCGIEKTGI-------------DLGV-N--VQV--AIKPDTQTPVLEW
TTATASLAFT----PA--------------------------------------------
------------------------------------------------------------
-------------------------------------------------ATQKTSSPLTR
SLLS--STHFLFLLLLEL-----PLLLG------MLGAVL-WVNRPQRR--S--------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------LWQSSP-V--IFLG----------------------------------------
----S--PNA--------EIR--EDP

PF07686 // ENSGT00470000042273_0_Domain_0 (207, 321)

ITGPG-AVSG------PEGGSLTVRCHYNPEWKT
H-RKLWCRG---AE--W----AACK-ILVET-AGTEE--EVKKDRVSIRDSWKDYTFNVT
MEVLRRDDADTYWCIIQRTGI-------------DKGV-Q--VKV--TIDPVPQSSAPER
TTTAARTTTG----SSPTV-----------------------------------------
--------------------------------------------I-------SSTR-VL-
-------KLGP-PHVA----SLMCP----------------------HTSKVTVKSEVSL
SFLT--SPFFLILVLLEL-----PLLLS------MLSAVL-WVNRPQRS--SA--G----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
----------------------------------------------------------MT
QRAG-AAMLPSA-------LLLLCV----PG-----------------------------
---------CLT---V-----------S

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 318)

GPS-TVMG------AVGESLSVQCRYEEKYKT
F-NKYWCRQ---PCL-----P-IWH-EMVET-GGSEG--AVRSDRVIITDHPGDLTFTVT
LENLTADDAGKYRCGIATILQEDGL----SGFLPDPFF-Q--VQV--LVSSAS-------
------------------------------------------------------------
---------STENSVKTP-A---------S---P--------------------------
---------------------------------------------------SR-PSQCQG
SLPS--NTCFLLLPLLKV-----PLLLS------ILGAIL-WVNRPWRT--PW--T----
-----------------------ES-----------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MWLLPA-------LLLLCF-----------------------------------
-------SGCLS---L-----------SG

PF07686 // ENSGT00470000042273_0_Domain_0 (210, 316)

PD-SVTG------TVGGSLRVWCQYESTYKG
Y-NKYWCRG---QYD------TSCE-SIVET-KGEEK--VERNGHVSIRDHPEALAFTVT
MQNLNEDDAGSYWCKIQTVWILDSW-------SRDPSA-L--VRV--YVSPATKTPR-RT
TRPA--------------------------------------------------------
--------------TT-----------PIF---LVVNPG---------------------
----------------------------------R--NLSTR------EVL----TKNSG
FQLS--SLHFLLVVLLKL-----PLLLS------MLGAIF-WVNRPQRA--PA--GK---
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MRLLVL----------LWGCLVL-------------------------------
-------PGYE--------------ALE

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 319)

GPK-EISG------FEGDTVSLRCTYREELRD
H-RKYWCRK---GGLLF----PRCS-GTIYA-GKEGQ--ETTEGRVSIRDSHQELSLIVT
LWNLTLQDAGKYWCGVEKRGP-------------DESL-L--ISL--FIFPG--------
--PCCPPSPSPTFQLL----ATTRLQPKAKTQQTQPPG--LTSPGLYPAGTTTKQGKTGA
EATPFPGTSRYG---------------------------HERTS-------QYAAT-SP-
-----H-AATS-PPA----G-----SSRP-PKQLD--STSAED---ASPA-LSSGSSKPR
VSIPMVRILAPVLVLLSLLS----A--A------GLIAFSSHLLLW-RK--EARQDMET-
-QRN----------EKVYLS---HLT----------------------------------
-------------------------------------------------------TEEEE
--APSQA-------PEGDVISM----PPLHTSEE---ELGFSKFVSV-------------
----------------------

------------------------------------------------------------
-------------------------MHRRCKPELRQNF----QSASGIRICHWLQIRWTR
SREGRAMWLSPA-L--LLLS----------------------------------------
----L--SGCF--------------SIRG

PF07686 // ENSGT00470000042273_0_Domain_0 (210, 349)

PV-SVRG------SEKGSVKVQCHYKRGWET
H-VKWWCRG---AR--W----VSCE-ILIQT-RGSEQ--EEKKDLVSIKDSHTDCTFTVT
MEGLRQNDSNIYWCGIQRLGP-------------DLGT-Q--VQL--TVDPEGAASAPAS
S-----------------------------------------------------------
------------------------------------------------------------
--------S------------------------------------------VNSSIRVSI
STHK--RNHYMLLVFVKV-----PILLI------LVGAIL-WLKGS-QR--VP--EEPG-
-----------------------DQPIYM--NFS-EL--LTKDMAA--------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
----MQ--------------------------------------------L---------
---------LVV-------LLLLCI----PG-----------------------------
---------SLS---L-----------S

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 319)

GPS-TVTG------AVGDSLSVECRYEEEYRA
F-HKYWCRQ---PRF-----P-LWQ-RTVQT-SGPEV--EAKSGRVSITDPPEDLAFTVT
LESLTADDAGKYRCGVATSLKEEGL----LSFLPDPFF-Q--VQV--IVSPASIAAS---
------------------------------------------------------------
---------SSNSSAWTS------------------------------------------
---------------------------------------------------GS-PSQQQG
PLLG--SAHFLLLVFLKV-----PLLLG------MLGAVL-CVHRPLRS--SA--D----
-----------------------RQS-----VHL--------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MRLLVL----------LWGCLVL-------------------------------
-------PGYE--------------ALE

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 319)

GPK-EISG------FEGDTVSLRCTYREELRD
H-RKYWCRK---GGLLF----PRCS-GTIYA-GKEGQ--ETTEGRVSIYDSRQELSLIVT
LWNLTLQDAGKYWCGIEKRGP-------------DESL-L--ISL--FVFPG--------
--PCCPPSPSPTFQLL----ATTRLQPKAKTQQTQPPG--LTSPGLYPAGTTAKQGKTGA
EATPFPGTSRYR---------------------------HERTS-------QYAAT-SL-
-----H-AATS-PPA----G-----SSRP-PKQLD--STSAED---ASPA-LSSGSSKPR
VSIPMVRILAPVLVLLSLLS----A--A------VLIAFSNHLLLW-RK--EAPQATET-
-QRN----------EKVYLS---HLPLGNGRDTEDA------VINTAGS-----MG----
---PLTIPEPSPNLHTE-IQYLSQT------------------------------TEEEE
--APSQA-------PEGDVISM----PPVHTSEE---ELGFSKFVSV-------------
----------------------

------------------------------------------------------------
-----------------------------------------------------------M
SPGHLALWLPSA-------LLLLQV-----------------------------------
-------PGCLL---L-----------T

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 317)

GPR-TVNG------TVGGSLSVQCQYEERYEK
H-GKYWFRD---SV------L-LYG-KIVET-TASSR--EARKGRVTIRDHPANLSFTVT
LENLTLQDAGSYWCGINVPWRQD--------P--DFEL-K--V----SVLPGEPLPLRVR
N----------------------------------------------------SS-----
---------KIPGTR---------------------------------------------
-------------------------------AP-------------SSEDAHC-HCVPCR
CLFS--SIHFLLLVFLKV-----PLFLS------MLSAIL-WVNRPQRG--SA--R----
-----------------------RPS-----HPEYE------NQ----------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
-----------------------VCKKRKGDRG----K----QKGPG----------QGQ
EREGRTMWLPPA-L--LLLS----------------------------------------
----L--PGCF-------------FSILG

PF07686 // ENSGT00470000042273_0_Domain_0 (210, 321)

PV-SVRG------PEQGSVTVKCHYNPRWKA
Y-NKWWCQG---AN--W----NVCR-ILVQT-TRSEK--ERKSGRVSISDNQRNHSFEVT
MERLRQEDTDTYWCGIEKRGT-------------DLGV-K--VIV--TVDPGKDCTCESD
YW--EPD-----------------------------------------------------
--------------------------------------G-------------------S-
--------T---------------------------------------------------
DAKS--LTHYMLLVFVKV-----PALLI------LAGAVL-WLKTP-LK--VP--KEQW-
-----------------------RQPIRM--NLNSER--LTKDTAP--------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MRLSLL-V--PFLF---W------------------------------------
----I--SGC--------CTA--QNPIT

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 335)

GPA-EVSG------QEQGSLTVQCRYTSDWKD
F-KKYWCRG---VP--Q----RKCD-ILVET-DTSEQ--LVEKNRVSIRDNQRDFIFTVT
MVDLRMSDAGIYWCGITKSGY-------------

ENSGT00470000042273_0_Linker_0_1 (335, 543)

DPMF-K--VIV--NIDPATQVPITVP
TT-------P----PITST-------------------------------T---------
---------------TI----------------FTVTTMVKETS-----------M-FP-
-------TLTS-YYY---------SDNGQ---------------GGG--DGGIGDGFLDL
SV

PF15330 // ENSGT00470000042273_0_Domain_1 (543, 727)

IL--PVTSAALLLLLL-----VA-----------SLFA-WRMVRRKK--KA--AEPP-
-------------SEQ-----A--QSLEG--DLCYA------NLSLKQPR--TSPG-S--
----SMS-SSGKDHQEE-VEYVTMAP---------------------FP------REEIS
YAALTLAG-FGQEPTYGNTGYL-VTQVPRTGLEE---ETT--EYSSIKRPLPAAMP----
----------------------

------------------------------------------------------------
----------------------------------------------------------MT
QRAG-AALLPSA-------LLLLCV----PG-----------------------------
---------CLT---V-----------SG

PF07686 // ENSGT00470000042273_0_Domain_0 (210, 317)

PS-TVMG------TVGESLSVQCQYEEKYKT
F-NKYWCRQ---PCL-----P-IWH-EMVET-RGSEG--MVRSDRVVITDHPGDLTFTVT
LENLTADDAGKYRCGIATILQEDGL----SGFLPDPFF-Q--VQV--LVSSAS-------
------------------------------------------------------------
---------STENSVKTP-G---------S---P--------------------------
---------------------------------------------------TR-PSQCEG
SLPS--CAYFLLLPLLKV-----PLLLS------ILGAIL-WVNRPWRT--P--------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
----------------MSKTLRGNLDKQSESAGVCR--ALGILPRFGFAAGCS-SRGAAK
WEGRT-MWLSLA-L--LLLS----------------------------------------
----F--PGCL--------------SI

PF07686 // ENSGT00470000042273_0_Domain_0 (208, 345)

QGPA-LVRG------PEQGSVTVQCRYSSRWQT
N-KKWWCRG---AN--W----STCR-VLIRS-TGSEK--ETKSGRLSIKDNQKNNSFQVT
MEMLRQNDTDTYWCGIEKFGT-------------DRGT-R--VKV--SVYSVGKDTMSTS
NQ-LSW------------------------------------------------------
----------------------------------------------------------S-
-------TV------------------------------------------DSGANMVSS
DLQK--RNHYMLLAFVKV-----PALLI------LAGAVL-WLKKSTQK--VP--EEQW-
-----------------------RHTLCS--DLDSEL--LAKDISP--------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MRLLVL----------LWGCLVL-------------------------------
-------PGYE--------------ALE

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 319)

GPK-EISG------FEGDTVSLRCTYREELRD
H-RKYWCRK---GGLLF----PRCS-GTIYA-GKEGQ--ETTEGRVSIHDSRQELSLIVT
LWNLTLQDAGKYWCGVEKRGP-------------DESL-L--ISL--FVSSG--------
--PCCPPSPSPTFQLL----ATTRLQPKAKTQQTQPPG--LTSPGLYPAGTTAKQGKTGA
EATPFPGTSRYG---------------------------HERTS-------QYAAT-SP-
-----H-AATS-PPA----G-----SSRP-PKQLD--STSAED---ASPA-LSSGSSKPR
VSIPMVRILAPVLVLLSLLS----A--A------GLIAFSSHLLLW-RK--EARQDMET-
-QRN----------EKVYLS---HLT----------------------------------
-------------------------------------------------------TEEEE
--APSQA-------PEGDVISM----PPLHISEE---ELGFSKFVSV-------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
-----MPLLM-L-Y--PLLF---W------------------------------------
----L--SGY---------SI--ATDISG

PF07686 // ENSGT00470000042273_0_Domain_0 (210, 319)

PM-TVNG------PERGSLMVQCVYNSGWET
Y-LKWWCRG---AT--W----YGCK-ILVKT-TGSEQ--EVKRDRVSIKDNQKNHTFTVT
MEDLMQTDADTYWCGIER

ENSGT00470000042273_0_Linker_0_1 (319, 542)

TGT-------------DLGV-T--VQV--IIDPAST----AA
PT--------------TSI-------------------------------S---------
---------------TT----------------FTAPVTPEETS-----------N-SP-
-------TLTG-HHL---------DK---------------------------RHNLLKL
S

PF15330 // ENSGT00470000042273_0_Domain_1 (542, 732)

VLL--PLIFTILLLLLV-----AA-----------SLLA-WRIMKCQQ--KA--AGMS-
-------------PEQ------VPQPLEG--DLCYA------DLTQQLTR--TSP-----
QKATTKLSFSAQADQVE-VEYVAMAP---------------------FP------KEDIS
YASLTLAA-EDQEPTYCNMGPL-SSHIPSRGPE----DPT--EYSIIRRP----------
----------------------

------------------------------------------------------------
------------------------------------------------------------
-------------M--YLSRTFLLL-----------------------------------
---CL--LGYLT---L----------

PF07686 // ENSGT00470000042273_0_Domain_0 (207, 319)

-STPR-ILEA------TVGGILVVKCQYGVDDEG
Y-GKFWCRG---AT--WQ----DCA-RVIET-EQLAEEEVVRRGRVTLRHIPSQRSFQVI
VVDLEEGDAGTYWCGVDKP-------------GSGPQA-P--VAV--TVF----------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
----------------------------------------------------------MT
QRAG-AAMLPSA-------LLLLWV----PG-----------------------------
---------CLT---V-----------S

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 318)

GPS-TVMG------AVGESLSVQCRYEGKYKT
F-NKYWCRQ---PCL-----P-IWH-EMVET-GGSEG--AVRSDRVIITDHPGDLTFTVT
LENLTADDAGKYRCGIATILQEDGL----SGFLPDPFF-Q--VQV--LVSSSS-------
------------------------------------------------------------
---------STENSVKTP-A---------S---P--------------------------
---------------------------------------------------TR-PSQCQG
SLPS--NTCFLLLPLLKV-----PLLLS------ILGAIL-WVNRPWRT--PW--T----
-----------------------ES-----------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MRLLLL----------LWGCLVL-------------------------------
-------PGYE--------------ALE

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 319)

GPK-EISG------FEGDTVSLRCTYREELRD
H-RKYWCRK---GGILF----SRCS-GTIYA-GKEGQ--ETTEGRVSIHDSRQELSLIVT
LWNLTLQDAGKYWCGVEKRGP-------------DESL-L--ISL--FVFPG--------
--PCCPPSPSPTFQLL----VTTRLQPKAKTQQTQPPG--LTSPGLYPAGTTAKQGKTGA
EATPFPGTSQYG---------------------------HERTS-------QYAAT-SP-
-----H-AATS-PPA----G-----SSRP-PKQLD--STSAED---ASPA-LSSSSSKPR
VSIPMVRILAPVLVLLSLLS----A--A------GLITFSSHLLLW-RK--EARQAMET-
-QRN----------EKVYLS---HLT----------------------------------
-------------------------------------------------------TEEEE
--APSQA-------PEGDVISM----PPLHTSEE---ELGFSKCVSV-------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MWLLPA-L--L-LI----------------------------------------
----L--SGC--------STA--QDAITG

PF07686 // ENSGT00470000042273_0_Domain_0 (210, 321)

PN-MVSG------HEQGSLTVRCRYDSSWKD
Y-KKYWCRG---AD--W----KTCE-ILVRT-DM-EQ--LMKKDRVSIRDDQTDFTVTVT
MEELRISDADIYWCAIERFGS-------------DHKF-K--VNV--NIDPET--TTV--
ILTT--------------------------------------------------------
-----------------------------------------------------MAP-VL-
-------TSAL-TTRK------SIAN---------------H--------GETQTSTLTW
SLLS--SIYFNLLVFLEL-----PLILS------MLSAVL-WVNRPQRC--SG--GGEVG
LGKV-----QS-----------------S--DAVDR----EKHLPVYRK-----------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
----------SS-I--LGFC----------------------------------------
----F--PGCL--------------SL

PF07686 // ENSGT00470000042273_0_Domain_0 (208, 335)

QGPE-SVRG------PERGSVTVQCHYNQGWET
Y-EKWWCRG---VK--W----HLCK-VLVQT-GGSEQ--EEKSGRVSIRDSWRDRSFTVT
MEGLRQDDADTYWCGIQKVGT-------------DLGT-R--VKV--ITDGEGSESTSLS
CTPG--------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------SDGI
VTCH--RTHYMLLAFVKV-----PILLI------LVGAVL-WLKGS-QR--VP--EE---
-------------------------LIYT--NLSSEL--PAKDTAP--------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
-----------------------------------------------------------R
HQKDGTMWLPSA-------LLLFSV----PGERGWAGLLTAAPLNPKSVSG--GPQA---
GAFSS--LG

PF07686 // ENSGT00470000042273_0_Domain_0 (190, 344)

SLS---L-----------SGPS-TVMG------TVGGSLGVQCRYEEKYKT
F-TKYWCRQ---PCL-----P-LWN-QLVAT-GQSEE--EMRSGRVSIVDHSGDLTFTVT
LENLTAADAGKYRCGIATIMHEEGL----HGFLPDLFF-Q--VQV--FVSPRALEEI---
------------------------------------------------------------
---------SSQGKRTRP-G---------V---WA-S----DT---------------W-
-------DQVG-----------WVG---V-SAW-------------EINSCLS-LCPSYR
SPLG--SVHILLLILLKV-----PF-LM------MLSAVL-WVNRPQWA--VC--G----
-----------------------ARS-----RPAED------KL----------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
-----MP-LLML-Y--PLLF---W------------------------------------
----L--SGY---------SI--ATDISG

PF07686 // ENSGT00470000042273_0_Domain_0 (210, 349)

PM-TVNG------LERGSLIVQCVYNSGWET
Y-LKWWCRG---AI--W----KGCK-ILVKT-TGSEQ--EVKRDRVSIKDNQKNHTFTVT
MEGLMQTDADTYWCGIERAGT-------------DLGV-T--VQV--T

ENSGT00470000042273_0_Linker_0_1 (349, 542)

VDPAST----AA
PT--------------TST-------------------------------S---------
---------------TT----------------FTAPVIPEETS-----------N-SP-
-------TLTG-HHL---------DK---------------------------RHNLLKL
S

PF15330 // ENSGT00470000042273_0_Domain_1 (542, 732)

VLL--PLIFTILLLLLV-----AA-----------SLLA-WRIMKCQQ--KA--AGMS-
-------------SEQ------VPQPLEG--DLCYA------DLTLQLTR--TSP-----
QKATTKLSFSAQADQVE-VEYVTMAP---------------------FP------KEDIS
YASLTLAA-EDQEPTYCNMGPL-SSHIPSVGPE----DPT--EYSIIRRP----------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MRLLVL----------LWGCLLL-------------------------------
-------PGYE--------------ALE

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 319)

GPE-EISG------FEGDTVSLQCTYREELRD
H-RKYWCRK---GGILF----SRCS-GTIYA-EEEGQ--ETMKGRVSIRDSRQELSLIVT
LWNLTLQDAGEYWCGVEKRGP-------------DESL-L--ISL--FVFPG--------
--PCCPPSPSPTFQPL----ATTRLQPKAKAQQTQPPG--LTSPGLYPAATTAKQGKTGA
EAPPLPGTSQYG---------------------------HERTS-------QYTGT-SP-
-----H-PATS-PPA----G-----SSRP-PMQLD--STSAED---TSPA-LSSGSSKPR
VSIPMVRILAPVLVLLSLLS----A--A------GLIAFCSHLLLW-RK--EAQQATET-
-QRN----------EKFCLS---RLT----------------------------------
-------------------------------------------------------AEEKE
--APSQA-------PEGDVISM----PPLHTSEE---ELGFSKFVSA-------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MWLPSA-------LLCLCL-----------------------------------
-------PGCLS---L-----------T

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 317)

GPG-YVNG------IEGTTLRVHCQYDKGYKG
Y-NKYWCRG---QND------IECE-SIVET-KGGEK--VEQNGRVSIRDHAHNLTMTVT
IEDLQEYDAGTYWCKIQTVWIWDAW-------SRDPAE-Q--VKV--HVTLATTAPL-GT
TLPP--------------------------------------------------------
--------------TTPT-TLPLRT--PAL---RLVIIR---------------------
----------------------------------R--NISTDM----E-TS----TCYPW
CLIS--SLHFLLLVFLKL-----PLFLC------MLCAVF-WVNRPQRA--AG--ER---
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MWLRSA-L--FLLI----------------------------------------
----L--PGCL---S----------

PF07686 // ENSGT00470000042273_0_Domain_0 (206, 321)

-ICGPK-AVSG------PERGSVTLQCCYDQGWED
Y-KKWWCPG---AD--W----GSCK-ILIKT-KESEP--EEKEGHLSIRDNKKSHTFTMT
MEDLREKDADTYWCGTERTGI-------------DLGF-Q--VEV--TLVPQSPTNAPEH
VTASTTE-----------------------------------------------------
----------------------------------LVRTDTATTS---------N-K-LR-
-------TFTS-SLI-----------RALPARLEQQE---RKFALPSSPF-F-----LPK
SLLC--NIYFLFLMCLKV-----TQLGG------LLFAIM-WLSRI---------QRTSG
A--------------T------ESQP----------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MHLLLL-F--PF-----W------------------------------------
----L--SGT--------ASQ--

PF07686 // ENSGT00470000042273_0_Domain_0 (204, 348)

MVRHTGPE-MVRG------WERNSVTVICRYGRGWDT
Y--KYWCRG---AK--W----NHCK-ILVQT-SGSEE--EVKKDRVSIRDNHRTKTFTVT
MKELRLNDTDTYWCGIERIGR-------------DHRH-Q--IQV--TVDSATPEETK--
------------------------------------------------------------
-------------------------------------------------------S-SS-
-------TVIS-RYT---------NG----------------------------XXXXXX
XXXX--XXXXXVLLLLLV-----AV-----------LLLK-WRMLKRQK--EA--AGRS-
-------------PEQ------ELQHPEG--E-IYT------NLTLQQTE--ASLS-SPQ
KKATD--PSLAQGDQEE-VDYTIIAS---------------------FQ------KEDIS
YATLSLDT-SNPEPTYGNMDYF-STHTPSRSQE----EHI--EYSIIRRT----------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------P---L-----------

PF07686 // ENSGT00470000042273_0_Domain_0 (208, 318)

QGPS-TVTG------TVGESLSVQCQYEEKYKS
N-VKYWCRRSL---L-------WCK-QIVKT-RPGK---EARSGRVSIRDHPPTLTFTVT
LENLSLEDAGIYNCGVDLPFINNSLGI-DHPLGIDDF--K--IMV--SVVPGKPTSC---
------------------------------------------------------------
---------------------------------------PDIL---------------C-
-------PG----------------------VS-------------FPHERRK-LDTIAG
CLLS--SIYFQLLVFLEL-----PLLLS------MLSAVL-WVNRPQRC--FG--E----
-----------------------KQH-----LPNYE------NQ----------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------YRKLLL-L--CVIV---WV-----------------------------------
-SSRS--AGS--------------

PF07686 // ENSGT00470000042273_0_Domain_0 (205, 318)

SAVSGPR-AVRG------VEQGSLTVRCRYDPGYEP
F-VKWWCRG---AD--W----SSCR-FIVKTNHGSEK--EVKQGRVSIKDNRKDRSFTVT
VEKLRVDDSDTYWCGIERVGV-------------DLGD-D--VDV--TIDPGKTMCVRGR
ILVF--------------------------------------------------------
----------------W----------------IS-SVFIQ-------------------
------------------------------------------------------------
QVIQ--PCCYCS---------------------------L-WPS----------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
----------------------------------------------------------MT
QRAG-APGLPSA-------LLLLCV----PG-----------------------------
---------CLT---V-----------SG

PF07686 // ENSGT00470000042273_0_Domain_0 (210, 317)

PS-TVMG------TVGSSLSVQCRYEEKYKM
F-NKYWCRQ---PCL-----P-FWH-ETVET-TGSET--VVRSDRVIITDHPGDRTFTVT
LENLTAEDAGKYRCGIATILQEDGL----SGLLPEPFF-Q--VQV--LVSSSS-------
------------------------------------------------------------
---------GTENSVKTS-G---------S---P--------------------------
---------------------------------------------------TG-PGQCQG
F--S--NVYFLLLLLLKV-----PLLLS------TLGAIL-WVSRPWRT--PW--T----
-----------------------EPW-----TGELI------I--PCDR----WY-----
---P-----AWRHN-------------------------------------------PSD
Y-RKDF------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-YMK

PF07686 // ENSGT00470000042273_0_Domain_0 (245, 317)

WWSQG---AD--C----DSCQ-FAVKT--PSEK--EVKKDHVSIKDNWEDHSVTMT
REKLRLDDSDTYWCGIERIGP-------------DLGD-D--VDV--TIVPGKSICCGYD
SSGP--------------------------------------------------------
---------------AL----------------SRDPAAPQREC----------------
----------------------------------------------------PRGGVA--
TYHL--ILVFSKFLLYCS-----QA-----------TRTL-WVSLPNLR--VS-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
-----------------------------------------------------------T
VNLCLLLWLSRK-ATTAILS----------------------------------------
----F--AGC--------------WAL

PF07686 // ENSGT00470000042273_0_Domain_0 (208, 340)

TGPE-EASG------PLGGSLSVQCQYKERYQK
Y-KKYWCRG---IF--L----FSCS-IVIQT-EGSEE--KLAGNRVSIHDNHTQSTFTVT
MESLAWNDTDTYWCGIDRPGF-------------DSMI-N--VNV--LVFSGKSFNSQTL
RPATQKS-----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
---------RDS-------CAGYLN-----------------------------------
-------LGCLA---L-----------T

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 318)

GPG-YVKG------IEGTTLHVHCRYDVGYKG
Y-KKYWCRG---EHD------IGCK-NIVGT-KGGET--VERNGRVSIRDHADDLTMTVT
IEDLQEDDAGTYWCKIQTMWIWDEL-------SRDVAE-M--VKV--NVILATTPVV-ST
LLPT--------------------------------------------------------
--------------THTS--------------------R---------------------
----------------------------------Q----NVSI----E-VS----TLYTR
SPLT--GLHLLLLVFLKL-----PVFLS------ILCAVF-WVNR---------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MRLLPA-------LLLLCL-----------------------------------
-------PGCLS--

PF07686 // ENSGT00470000042273_0_Domain_0 (195, 345)

-L-----------TGPS-YVMG------TTGGSLSVQCHYEEMYKG
Y-NKYWCRG---QYD------TACN-IIVET-KGEER--EERNGRVSIRDCADKLTFTVT
MENLNADDAGTYWCRIQTVWILDAW-------SYDPSV-Q--VKV--FVFPASSTTTGRT
TRPA--------------------------------------------------------
--------------AP-----------ATL---PVVNTR---------------------
----------------------------------Q--NVST------GEVLT--HS--SG
SPLS--NIHFLLLVFLKL-----PLFLS------MLAAVL-WVNRPQRG--PG--GR---
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MRPLVL----------LWSCLVL-------------------------------
-------PGYE--------------ALK

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 340)

GPK-EISG------FEGDSVSLQCTYEKRVRG
H-RKYWCRE---GGLVL----SRCS-DIVYS-S-QNQ--DVARGRMSIRDSPRELSMTVT
MRDLTLKDSGKYWCGIDRLGF-------------DESF-E--VSL--IVFPGKRDSPI-P
TGTCCPSTPNPSFQPLTATRS---LQPKAKAWQTQVPE--LTSPGLHPTVVTAKQGKTGV
KAPVFTEVALLAGSAGTSQVLPGTSPYAGSSPHTATPARSPGTSP-SPGTSPYAGS-SP-
-----H-TATS-PHA----GSS-----RP-GIWLA--PTTAKD---SKA----GSVSKAS
VSIPMVRMMAPVWVLLSLLL----A--A------GLIAFGSHMLQW-RK--K--------
-------------------------PPGNSWAPEDA------MINLAAP-----PE----
---YLGNPKPSAVPSTE-TQQLGQT------------------------------TEEEA
--APPLD-----SE--EDKMAA----PPLQMSAE---ELAFSEFISV-------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MWLFPA-L--L-LF----------------------------------------
----L--PGC--------STA--QDAIT

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 319)

GPS-MVRG------QERGSLTVRCRYDSSWKD
Y-NKYWCQG---AD--W----RTCE-TLVKT-DASEK--LVKKNRVSIRDDQTDLIFTVT
LEDLRISDAGVYWCGIDRIGY-------------DPNF-E--VNV--NIDP--EVSTV--
IMTT--------------------------------------------------------
-----------------------------------------------------TAP-FL-
-------TSTP-STTE------NIGN---------------H--------GETQTSAPTW
SLLS--SIYFQLLVFLEV-----PLLLS------MLSAAL-WVNRPQRC--SG--GGEAG
LEKV-----QS-----------------S--DAWYR----EEHFYVDRK-----------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
---------SWD-------GCGLCF-----------------------------------
-------PG

PF07686 // ENSGT00470000042273_0_Domain_0 (190, 348)

CLS---L-----------VGPR-FVTG------TTGDSLTVRCRYEQDYKG
Y-NKYWCRG---QYD------TDCN-KIVET-QGTER--EERSGRVSIRDNADSLTLTVT
MENLNAADAGSYWCKIQTVWILDEW-------SRDPSF-Q--VQV--SVSPAPRTTTRRT
THPA--------------------------------------------------------
--------------TP-----------ATF---PTVTAG---------------------
----------------------------------Q--NFST----------N--HC--PG
VPLS--TVHFLLLIFLKL-----PLFLG------VLGAVL-WVSRCQKG--PG--GR---
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MWLPWA-------LLLLW------------------------------------
----V--PGCFA---L-----------R

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 321)

GPG-TVAG------PVGGSLSVQCWYEEKHKT
L-NKYWCRQ---RWL-----LP-CD-KIVDT-KGSAE--E-MNGRVSIRDCPANLSFTVT
LKNLTEEDAGTYWCGVDTPW

ENSGT00470000042273_0_Linker_0_1 (321, 554)

HK------------DPIV-Q--VEV--SMSPAST-SMTPT
SITA--------------------------------------------------------
---------A-KTSTITT-V---------F---PPVSSTSLFA---------------V-
-------SAT---H-----STSNWKENEEVVS----------------------------
SQLP---------

PF15330 // ENSGT00470000042273_0_Domain_1 (554, 730)

LLLSL-LALLLLLLM------GASLLV-WRMFQK--WIKA--GEHSE
LSQN---------PKQ-----AAEQS-----ELHYV------NLELRS-----WP-----
---LQEE--PAPPREVQ-VEYSTVA----------------------AP------REELH
YASVVFD--S-----NTNRIAA------QRPRE----KEPDSHYSVIKKT----------
----------------------

------------------------------------------------------------
--MSENTKETWT-S---RKWMTQAL-----------------LHILGFQLGPRF--AEDG
SQGDRTMWLLPA-------LLLLCL-----------------------------------
-------SGCLS--

PF07686 // ENSGT00470000042273_0_Domain_0 (195, 318)

-L-----------TGPG-SVNG------TAGGSLRVRCQYESMYEG
Y-NKYWCRG---QYD------TSCE-SIVET-KGEEK--VERNGRVSIRDHPEAFAFTVT
MQNLNEDDAGSYWCKIQTVWILDSW-------SRDPSA-L--VRV--YVSSATTTPR-RT
TRPA--------------------------------------------------------
--------------TP-----------PIF---LVVNPG---------------------
----------------------------------Q--NLSTG------EVL----TQNSG
FRLS--SPHFLLVVLLKL-----PLLLS------MLGAVF-WVNRPQWV--PA--GR---
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MRPLVL----------LWGCLLL-------------------------------
-------PG

PF07686 // ENSGT00470000042273_0_Domain_0 (190, 345)

YE--------------ALMGPK-KIRG------FEGDTVSLQCTYEEKLRE
H-KKYWCKK---GGILV----SRCS-GIIYA-REDGE--ERTEGRVSIQDDPQKLTLTVT
LRELT-QDSGDYWCGVNILGI-------------DETF-L--VSL--LVLPG--------
--PCCPPSPTPSFQPL----AT-SLQPKAKAWQTQPPA--STSPGAHPTVT--KQGKTEA
EASPFTGTSPPE---------------------------PAGTSL-YTGTSPYAGN-TPN
EERPLH-RATS-PHA----GTS-----RP-STYLD--STSTED---PTSS-ALDTQSHPR
ASHSKAHILVPVLVLLVLLL----A--A------GLAVVGRCVLRC-RK--EVQLDPKT-
-Q-N----------EKVHLS---HLAL---------------------------------
--------------------------------------------------------KEEE
--ASFQD-------PAGAAKPG----PPLHMSEE---ELRSSVFIPV-------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MWPLTV----------LWGCLLL-------------------------------
-------PGYR--------------AMVG

PF07686 // ENSGT00470000042273_0_Domain_0 (210, 319)

PK-EISG------FEGDTVSLQCTYREELKT
Y-SKYWCRE---RGIFV----SHCS-NTIYA-REDGQ--ETTEGRVSIQDSPQTLTLSVT
LRKLTLQDAGKYFCGVSKLGR-------------DESF-L--VSL--LVFPGNKCLSFPQ
VGPCCPPSPTPSFQPL----ATTSLQPKAKAWQTQPPELR--------------------
------------------------------------------------------------
-------------------------TSRL-SKRPD--SSSAED---TTLA-PSSSSSVSR
VSIPMVRILAPVLVLLALLL----A--A------GLAALGSYLLRW-RK--EAHLAAET-
-QRN----------EKVHLS---HSHSSCGWPLEYP------VINPTGP-----SG----
---PHASPEPAASPCTE-IQCLSQS------------------------------SEESE
--APLQD-------PEENIIPG----PPLHMSEE---ELCFSKFISV-------------
----------------------

------------------------------------------------------------
-------------------------MHRRCKPELRQNF----QSASGIRICHWLQIRWTR
SREGRAMWLSPA-L--LLLS----------------------------------------
----L--SGCF--------------SIRG

PF07686 // ENSGT00470000042273_0_Domain_0 (210, 349)

PV-SVRG------PEKGSVKVQCHYKRGWET
H-VKWWCRG---AR--W----VSCE-ILIQT-RGSEQ--EEKKDLVSIKDSHTDCTFTVT
MEGLRQNDSNIYWCGIQRRGP-------------DLGT-Q--VQL--TVDPEGAASTPAN
S-----------------------------------------------------------
------------------------------------------------------------
--------S------------------------------------------VNSNIRVSI
STHK--RNHYMLLVFVKV-----PILLI------LVGAIL-WLKGF-QR--VP--EEPG-
-----------------------DQPIYM--NFS-EL--LTKDMAA--------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MWLSPA-L--LLLS----------------------------------------
----L--SGCF--------------SIY

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 344)

SQE-SVRA------PEQGSVTVQCHYQQRWET
Y-VKWWCRG---VH--W----DSCT-ILVQT-RGSEQ--EEKRDRVLIKDNQRDHVFTVT
MEELRQNDTDIYWCGIKRLGT-------------DLGT-Q--VKV--IIDPVGAASTPAS
SS---S------------------------------------------------------
--------------------------------------K-------------------L-
--------T------------------------------------------TNRNMGVFI
SSHK--RTHYVLLVFVKV-----PILLI------LVGTIL-WLKGS-QR--VP--EKPW-
-----------------------EQPIYM--NLSSKH--LNKDMAA--------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MRLPPA-L--LLLS----------------------------------------
----L--PGCL---S-----------IRG

PF07686 // ENSGT00470000042273_0_Domain_0 (210, 349)

PE-SVWG------RERESLSVQCHYDSGWET
S-KKWWCRG---AW--W----ASCR-ILVET-QGLER--EEKGARVSIKDNQRNRSFTVT
MQELRPDDADTYWCGIENPGA-------------NLGT-Q--IKV--TVGPSKSLLSTLR
G-----------------------------------------------------------
-------------------------------------PGAQDWKN-------EV-P-SP-
-------PLPE-GRRERMVSESECEQDQGTDGWGGRGRDQGRASLPSPAA-HR----IPE
VSLR--PLQ---------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MRPLLM----------LWGCLVL-------------------------------
-------PGYG--------------SVV

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 319)

NPK-EISG------FEGDTVSLQCTYEEELKK
H-QKYWCRE---AGLFI----SRCT-GTVFS-GEYGQ-----EGRVSVHDNPRENRFTVI
LRNLTLKDRGKYLCGVKRLGF-------------DKTM-S--VSL--LVFPG--------
------------------------------------------------------------
-------------------------------------------------TSLHPAT----
----------S-PPA----GIS-----QP-ATQLD--STSTED---TSFV-PSS-SSKSR
VSIPLIRILAPVLVLLALLL----A--T------GLAALGNYMFQR-RE--KAQLASET-
-QKK----------DKVHLS---HLT----------------------------------
-------------------------------------------------------SEDDE
--ASWRD-------PKGDMTPA----STLPMSGD---EPGFSKFSSV-------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------VWLPSA-------LLLLG------------------------------------
----V--PG

PF07686 // ENSGT00470000042273_0_Domain_0 (190, 350)

CMM---L-----------RGSH-T-IG------IVGESLSVQCPYEKKYEE
N-DKYWCRG---STF-----AL-CD-KIVET-RGSEK--EKRNGRVSIRDHPAWLYFTVN
VTNLTVEDADVYWCGIDKMWLDDS-------------I-Q--VVV--SVSPAPK----SS
TPTR--------------------------------------------------------
---------T-RTSTTTT-E---------D---PPVPSTVLIT---------------T-
-------GAT---H-----STSLEILS--EPE----------------------------
SGLS---------VLLAF-LVALLLLLV------GASLMV-WRMVRR--RAKA--AENTE
LPLK---------PSQ-----AAALS-----EPCYA------NLELQT-----PL-----
---KEP------PRDTE-VEYSTV------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MWLSPA-L--LLLS----------------------------------------
----L--S------------------------------------

PF07686 // ENSGT00470000042273_0_Domain_0 (225, 345)

HGSMTVQCHYQQRWET
Y-VKWWCRG---MH--W----DSCT-ILIQT-DGSEQ--EEKRDRVLIKDNQRDHVFTVT
MGGLRQNDTDIYWCGIERIGT-------------DLGT-Q--VKV--IVDPVRAASTPAS
SS---S------------------------------------------------------
--------------------------------------K-------------------L-
--------T------------------------------------------TNRNMGVLI
SSHK--RTYYVLLVFVKV-----PILLI------LVGTIL-WLKGS-QR--VP--EKPW-
-----------------------EQPIYM--NLSSKH--LNKDMAA--------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MRLLVL----------LWGCLVL-------------------------------
-------PGYE--------------ALE

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 319)

GPK-EISG------FEGDTVSLRCTYREELRD
H-RKYWCRK---GGLLF----PRCS-GTIYA-GKEGQ--ETTEGRVSIRDSRQELSLIVT
LWNLTLQDAGKYWCGVEKRGP-------------DESL-L--ISL--FVFPG--------
--PCCPPSPSPTFQLL----ATTRLQPKAKTQQTQPPG--LTSPGLYPAGTTAKQGKTGA
EATPFPGTSRYG---------------------------HERTS-------QYAAT-SP-
-----H-AATS-PPA----G-----SSRP-PKQLD--STSAED---ASPA-LSSGSSKPR
VSIPMVRILAPVLVLLSLLS----A--A------GLIAFSSHLLLW-RK--EARQDMET-
-QRN----------EKVYLS---HLT----------------------------------
-------------------------------------------------------TEEEE
--APSQA-------PEGDVISM----PPLHTSEE---ELGFSKFVSV-------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MWLSPA-L--LLLS----------------------------------------
----L--S------------------------------------

PF07686 // ENSGT00470000042273_0_Domain_0 (225, 349)

HGSVSVQCHYQQRWET
Y-VKWWCRG---VH--W----DSCT-ILIQT-RGSEQ--EEKRGRVVIKDNQRDHVFTVT
MGGLRRNDTDIYWCGIKRRGT-------------DLGT-Q--VKV--IVDPVGAASTPAS
SS---S------------------------------------------------------
--------------------------------------K-------------------L-
--------T------------------------------------------TNRNMSVFI
SSHK--RTHYVLLVFVKV-----PILLI------LVGAIL-WLKGS-QR--VP--EKPW-
-----------------------EQPIYM--NLSSKH--PNKDMAA--------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
-----------------------------------------------------------M
TARAWASWRPSA-------LLLLLV-----------------------------------
-------PGCFP---L-----------R

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 345)

GPS-TVDG------PVGGSLSVQCWYEEKHKT
L-NKYWCRP---PRV-----L-QCN-KIVET-KGPAG--K-MNSRVSIRDSPENLSFTVT
LENLTEEDAGTYWCGVNTPWLQD--------L-YDPTV-Q--VEV--SVFPAS-------
------------------------------------------------------------
---------SPQSSMGTS-G---------P---PP--KLPVHT---------------W-
-------P-----------------------SV-------------TRKDSPE-PSPHPG
SLFS--NVRFLLLVLLEL-----PLLLS------MLGAIL-WVNRPRRS--SR--S----
-----------------------RQS-----WPEGE------NQ----------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
-----------------------------------------------------------M
TLGNGRAWLPTA-------LLLLQV-----------------------------------
-------PGCSS---I-----------S

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 316)

GPT-SVTG------TVGGSLSVQCSYEEQLRE
H-SKYWCKR---PCF--------WK-TV-ET-KRSNR--EVRNGHVSIRDHPASLTFTVT
LENLTEDDAGIYRCGIDTSWLGG--------YLEDPAV-H--IVV--SVTPGSTEAP---
-----------------------------------------------------SI-----
---------M--RSTSPP-G---------L---HK--TLPAP------------------
---------------------------TG-STA-------------IQQETPS-PSRHPG
SLLS--SVYFLLLVFLEV-----PLLLS------MLSVVL-LVTRPQRG--SG--G----
-----------------------WAE-----SA---------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MPLLTL-Y--LLLF---W------------------------------------
----L--SGY---------SI--VTQIT

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 349)

GPT-TVNG------LERGSLTVQCVYRSGWET
Y-LKWWCRG---AI--W----RDCK-ILVKT-SGSEQ--EVKRDRVSIKDNQKNRTFTVT
MEDLMKTDADTYWCGIEKTGN-------------DLGV-T--VQV--T

ENSGT00470000042273_0_Linker_0_1 (349, 542)

IDPAST----PA
PT--------------TPT-------------------------------S---------
---------------TT----------------FTAPVTQEETS-----------S-SP-
-------TLTG-HHL---------DN---------------------------RHKLLKL
S

PF15330 // ENSGT00470000042273_0_Domain_1 (542, 732)

VLL--PLIFTILLLLLV-----AA-----------SLLA-WRMMKYQQ--KA--AGMS-
-------------PEQ------VLQPLEG--DLCYA------DLTLQLAG--TSP-----
QKATTKLS-SAQVDQVE-VEYVTMAS---------------------LP------KEDIS
YASLTLGA-EDQEPTYCNMGHL-SSHLPGRGPE----EPT--EYSTISRP----------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------Y--------SIA---TEITGPT-TVNG------L----

PF07686 // ENSGT00470000042273_0_Domain_0 (228, 348)

-ELRCAYGSQWET
Y-LKWWCRG---AV--W----SSCE-ILVKT-TGSEQ--EVKRDRLSIRDDQKNHAFTVT
MKDLRRDDADTYWCGIERTGT-------------DLGV-K--VQV--TIDPGK-RESPEW
TTTTASLART----AA--------------------------------------------
------------------------------------------------------------
-------------------------------------------------ATPKTTAPITR
SLLR--STHFLVLVLLEL-----PLFLS------MLGAIL-WVNRSPRR--S--------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
-----------------------------------------------------------M
TARAWASWQSSA-------LLLLLV-----------------------------------
-------PGYFP---L-----------SH

PF07686 // ENSGT00470000042273_0_Domain_0 (210, 318)

PR-TVAG------PVGGSLSVQCHYEKEHRT
L-NKFWCRP---PQI-----F-LCD-KIVET-KGSAG--K-RNGRVSIRDSPANLSFTVT
LENLTEEDAGTYWCGVDTPWLRD--------F-HDPVV-E--VEV--SVFPAGTT-----
----------------------------------------------------TAS-----
---------SPQSSMGTS-G---------P---PT--KLPVHT---------------W-
-------P-----------------------SV-------------TRKDSPE-PSPHPG
SLFS--NVRFLLLVLLEL-----PLLLS------MLGAVL-WVNRPQRS--SR--S----
-----------------------RQN-----WPDGE------NQ----------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------G

PF07686 // ENSGT00470000042273_0_Domain_0 (210, 321)

PK-DISG------FEGDTVSLKCTYRKEERE
R-KKYWCKQ---IGFLV----HRCS-STIYS-GEDGQ--VITQGRVSICDNPQELAFTVT
LRDLTLQDAGKYWCGADKLGF-------------DETF-L--VSL--TVFPGNKLLSLP-
-RPCCPPSPTLFLQPL----STASLQPQAKARQTQPPPERPAPPDLHLAVTTAKQGKTGT
EASPVTGTVPLQ---------------------------HAGTTT-HTGTSPYAGT-SA-
-----H-TATS-PHA----GSS-----RP-PMPLD--STLAED---TSPV-PISHSSRSR
VSIPMVRILAPVLVLLSLLL----A--A------GLIASGSLLLRW-RK--KAQLALET-
-QKN----------EKVHLP---TLVRTEADKSTSW------DSCGAGD-----LL----
---------GSAHLCLP-PDPRGRT------------------------------TEELE
--APSLD-------PMESTIPD----PLPLMSEE---ELGFSKFISV-------------
----------------------

------------------------------------------------------------
-----------------------------------------------------------M
NKQERFPLSPLLLL----PSLLLFL-----------------------------------
---CP--EDCLS---L----------

PF07686 // ENSGT00470000042273_0_Domain_0 (207, 335)

-SGTR-EVIG------TVGETLTVQCFYEKAYKN
A-MKYWCRK---QML------ILCD-KTVIS-TS------NGNGRVSVRDHPENQTFIIT
MKNLTEADEGAYWCGIDILG-------------LDSLN-T--ITV--SVVPAPRV-T-PN
TYTT--------------------------------------------------------
---------TLP-----T-EIPM---------------TN-ET---------------E-
-------------R-----EKTSEEISDH-------------------KKLQR-PWILEK
PG-----------ILLSV-LGFLIILLV------GALFLT-WRLIVRQKKGEC--ATSGH
IFF---------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
--------------------MTQAL-----------------LQTSGFYLGPGF--AKNA
SQGDRTMWLLLA-------LLLFFL-----------------------------------
-------PG

PF07686 // ENSGT00470000042273_0_Domain_0 (190, 348)

CLS---L-----------TGPS-FVTG------TAGSSLTVRCRYDQAYKG
Y-NKYWCRG---EYD------TDCH-TIVET-KGEER--EERNGWVSIRDSADDLAFTVT
MRNLDAADAGPYWCKIQTVWILDAW-------SRDPSF-Q--VQV--SVSPARTTT-RRI
TRLT--------------------------------------------------------
--------------TP-----------AAF---SAVITT---------------------
-------------------------------------------------VRT--H--HSG
IPLS--TVHFLFPIFLKL-----PLFLS------MLGAVL-YMSRRQRG--RG--RW---
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------M

PF07686 // ENSGT00470000042273_0_Domain_0 (225, 319)

GESLNVQCPYEEEYKM
S-DKYWCKG---SF--RV----SCS-PIVEI-KGSQE--EAKKDRVSIRDSRQNRTFTVT
MENLAAEDAGSYACGIDKFL------------KFDPLL-W--FTV--SISQVPEVRSTTI
TQSP--------------------------------------------------------
---------S------AA-A----------------------------------------
-------------E-------TSVTSTSAHRI-GG----------E--TAFPT-SG----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MWLFPA-L--L-LF----------------------------------------
----L--PGC--------STA--QGAITG

PF07686 // ENSGT00470000042273_0_Domain_0 (210, 319)

PS-IVRG------QERGSLTVRCRYDSRWKD
N-KKYWCRG---AD--L----NACE-ILVKT-NTSEK--LV-KNRVSIRDDQIDLIFTVT
MEDLRISDAGIYWCGIDRVGY-------------DPSF-K--VNV--NIDPAPEVSTV--
IMTT--------------------------------------------------------
-----------------------------------------------------MAP-VL-
-------TPTL-STRE------NTGN---------------H--------GETQTSAPTW
ALLS--SIYFQLLVFLEV-----PLLLS------MLSAAL-WVNRPQRC--SG--GGEVG
LEKV-----QS-----------------S--DVR--------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------SWLPEDPE--ALTGSPDSF-----------------------------------
---IH--SSVQA---L-----------

PF07686 // ENSGT00470000042273_0_Domain_0 (208, 337)

SGPE-EAEG------PEGGSLTLRCVYKDGMQS
A-PKYWCRA---GGLFLT----RCS-QSVKT-SGSEV--EATNGPMSIRDSHRDRAFTVT
MKELTTQDAGHYLCGVERF-------------GFDDTL-R--VTV--TV-----------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
----------------------------------------------------------MT
QRAG-AALLPSA-------LFLLCV----PG-----------------------------
---------CLT---V-----------S

PF00047 // ENSGT00470000042273_0_Domain_0 (209, 319)

GPS-TVMG------TVGESLSVQCQYEEKYKM
F-NKYWW---------------------------SEG--VVRSDRVAITDHPGDLTFTVT
LENLTVDNAGKYRCGIATILQEDGL----SGLLPDPFF-Q--VQV--LVSSGE-------
------------------------------------------------------------
---------PPFT-----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MWLPWT-------LLLLW------------------------------------
----V--PGCFA---L-----------SG

PF07686 // ENSGT00470000042273_0_Domain_0 (210, 318)

PS-TVAG------PLGGSLSVQCGYEEEHRT
L-NKYWCRV---RWT-----IR-CD-KIVET-KESAG--KLRNSRVSIRDHPANLSFTVT
LENLTEDDAGTYWCGVD

ENSGT00470000042273_0_Linker_0_1 (318, 554)

TPLLRDL---------HDPII-K--VEV--SVFPAST-SATLT
SVTA--------------------------------------------------------
---------A-RTSAITT-A---------F---PPVPSTTLLT---------------V-
-------SAT---H-----STGIQGDNEEVVN----------------------------
FKLP---------

PF15330 // ENSGT00470000042273_0_Domain_1 (554, 733)

LLLSL-LALLLLLLV------GASLLV-WRMFQK--RVKA--GEHSE
LSQN---------HRQ-----AVEES-----EQHYA------NLELLT-----WP-----
---LQEE--PALPTQVE-VEYSTVA----------------------AP------REELH
YASVVFD--SQSQNSNANRIAA------QRPRE----EEPDSNYSVIRKT----------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------

PF07686 // ENSGT00470000042273_0_Domain_0 (190, 348)

CLP---L-----------TGPD-SVTG------APGGSVSVQCRYEEVYRG
S-NKYWCRG---PYD------LSCD-TVVET-KGGAR--EERNGRVSIRDHAENLTFTVT
MENLTAGDDGPYWCRIQSTWILDVL-------SYDPSV-R--VNV--SVS--ASAPE-NT
IPAV--------------------------------------------------------
--------------TP-----------PTF---LLGTAG---------------------
----------------------------------Q--NLSTC------EMF----THHPQ
SLLC--SVHFLLL-----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--LCL--PGCLM---L-----------IGPS-MVTG------AV

PF00047 // ENSGT00470000042273_0_Domain_0 (225, 316)

GESLSVHCQYEEKFKE
N-DKYWCRE---QLF-----K-PCD-KIVET-RGLER--EKAKGRVSLRDHPSQLNFTVT
LRNLTVEDEGIYWCGIHVTWAKDGL------LLFDPIF-R--VVV--SVSPASALTT---
-----------------------------------------------------AS-----
---------SSESSTRTL-G---------P---PT--SLPAHT---------------R-
-------P-----------------------ST-------------TGQETSE-LRPKLR
SLLS--SIHFLLLVFLKV-----PLLLS------MLSAVL-WVNRPLWG--PR--G----
-----------------------KQC-----QPGSK------SQ----------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MRLLVL----------LWGCLVL-------------------------------
-------PGYE--------------ALKC

PF07686 // ENSGT00470000042273_0_Domain_0 (210, 316)

PE-EISG------FEGDTVSLECTYREELRD
H-PKYWCRE---AGLLF----SRCA-GTIYS-GEEGQ--ETTEGRVSIRDSRQELSFTVT
LRDLTLKDAGKYWCGVKKLGG-------------DKYL-P--ITL--VVFPA--------
--S----------------------------------------PGLYPAVTTAKQGKTVA
KATPFPGTSRYG---------------------------HEGNS-------QCTGT-SP-
-----H-AATS-PPA----G-----SSRP-VMHLD--STSAED---ASPA-LSSGSSKPR
LSIPLVRILAPVLVLLSLLG----A--A------GLIAFSSHLLRW-RK--KAQLATET-
-QRN----------EKVYLS---HLPLGNSQDPEDA------RSSLAGP-----MG----
---PLTIPEPSASLYTE-IQYLSQT------------------------------TEKEE
--APSQA-------REGDVVSP-----PLHTSEEDQEDLGFSKFVSA-------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MWLPSA-------LLLLW------------------------------------
----V--PGCFS---L-----------GG

PF07686 // ENSGT00470000042273_0_Domain_0 (210, 349)

SN-TVTG------SVGGSLSVQCPYKEEYRT
A-KKYWCKG---RFA-----VL-CD-KIVET-KDSER--EARTSRVSITDHPENLNFTVT
MRSLTVEDTGTYWCGVDK-Q---F---------LDVTS-E--FEV--T

ENSGT00470000042273_0_Linker_0_1 (349, 554)

VSPAST-PVVPT
TITI--------------------------------------------------------
---------V-TTLTVTT-E---------V---PTVPSTALSA---------------V-
-------SAT---C-----SASIQDEPQKSFG----------------------------
PRLS---------

PF15330 // ENSGT00470000042273_0_Domain_1 (554, 732)

LLLSL-LAFLLLLLV------GISLLA-WRMFQK--QVKA--GEPPA
LSQG---------PRQ-----AAEQS-----EQHYV------NLELLT-----RP-----
---LREE--PVPARQVE-VEYSTLA----------------------AP------REEPH
YTSVVFD--HQSQGSNAHGISA------QRPRE----KEP--EYSVIRKK----------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MRLLVL----------LWGCLLL-------------------------------
-------PGYE--------------ALE

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 319)

GPE-EISR------FEGDTVSLQCTYREELRD
H-RKYWCRK---GGILF----SRCS-GTIYA-EEEGQ--ETMKGRVSIRDSRQELSLIVT
LWNLTLQDAGEYWCGVEKRGP-------------DESL-L--ISL--FVFPG--------
--PCCPPSPSPTFQPL----ATTRLQPKAKAQQTQPPG--LTSPGLYPAVTTAKQGKTGA
EAPPLPGTSQYG---------------------------HERTS-------QYTGT-SP-
-----H-PATS-PPA----G-----SSRP-PMQLD--STSAED---ASPA-LSSGSSKPR
VSIPMVRILAPVLVLLSLLS----A--A------GLIAFCSHLLLW-RK--EAQQATET-
-QRN----------EKVCLS---HLT----------------------------------
-------------------------------------------------------TEEKE
--APSQA-------PEGDVISM----PPLHTSEE---ELGFSKFVSV-------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MRPLLM----------LWGCFVL-------------------------------
-------PGYG--------------SVV

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 321)

DPK-EISG------FEGDTVSLQCTYGEELKK
H-QKYWCRE---AGLFI----SRCT-GTVFS-GEYGQ-----EGRVSVHDNPRENRFTVI
LRNLTLKDTGKYWCGVKKLGF-------------DKTM-S--VSL--LVFPV--------
------------------------------------------QHKRGVPEA---------
-TSPFARIS--P---------------------------HPAASP-YAGTSLHPAA-SP-
-----F-ARIS-PHP----GIS-----QP-ATQLD--STSTED---TSFV-PSS-SSKSR
VSVPLIRILAPVLVLLALLL----A--T------GLAALGSCMFQW-RE--KAQLASET-
-QKK----------DNVHLS---HLALGNSCVPEST------VIKLAEP-----TG----
---PPASPEPSASSNTE-IWCLSQT------------------------------SEDDE
--ASWRD-------HKGDMTPA----STLPMSGD---SWAFQSSAQSSHRTLSLN-----
---LWKG---------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------IRG

PF07686 // ENSGT00470000042273_0_Domain_0 (210, 321)

PK-VMRG------PERGSLTVRCCYGQGWKT
Y-RKWWCRG---AD--W----ASCK-ILVIT-TGSEQ--EVKQDRVSIRDDQRNLTFTVT
MEELRRDDEDTYWCGIKRTGT-------------DPGF-Q--VKV--TIDPAPVT-----
------------------------------------------------------------
---------------------------------------PEKIQ-----------V-SP-
-------TVTS-HHS------------ES------------------------SSVSLKL
SVLI--PLIFAVLLLLSV-----AA-----------SLLA-WRMVKQRE--KA--PEIS-
-------------QEQ------VLQPLES--DVCYA------NLTLQHTG--TSSG-PSR
KKASRKPSYFAQVDQVE-GEYVTMDS---------------------IP------REDIS
YPALSLDT-LDQEPTYSNTSHL-VAHSPSGSHA----EPT--EYSTIRKP----------
----------------------

------------------------------------------------------------
-----------------------------------------------------------M
TQLASAVWLPMLLL----LLLLFW------------------------------------
----L--PGCVP---L-----------H

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 318)

GPS-TVTG------TVGESLSVSCQYEEKFKT
K-NKFWCRV---S-L-----KGLCK-DIVKT-SSS-E--EARNGRLTIRDHPDNLTFTVT
FESLTLEDADTYLCVVE

ENSGT00470000042273_0_Linker_0_1 (318, 555)

LPFF-------------HKFF-M--IEL--SVVPSED----PV
SS----------------------------------------------------------
---------P-----GPT-L---------E---TPVVSTSLST---------------K-
-------GPL---Q-----GSITEGRHEHHDPQ-G-------------------------
LRLP---------V

PF15330 // ENSGT00470000042273_0_Domain_1 (555, 733)

LLSV-LALLLFLLL------GTSLLA-WRMFQK-RLVKA--DRHPE
LSQN---------LRQ-----ASEQN-----ECQYV------NLQLHT-----WS-----
---LREE--PVLPSQVEVVEYSTLAL---------------------PQ-------EELH
YSSVAFN--SQRQDSHANGDSL------HQPQD----QKA--EYTEIRKPRKGLSDPHL-
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MRPLVL----------LWGCLVL-------------------------------
-------PGYG--------------VLVG

PF07686 // ENSGT00470000042273_0_Domain_0 (210, 318)

PK-EISG------FEGDTLSLQCTYGEELKK
H-KKYWCRE---GGLLI----SRCS-GTIYA-EEDGQ--ERTAGRVSVWDSPEELTLTVT
LRNLTLQDAGKYWCGVSRLGF-------------DWSF-L--VSL--RVLPGNTSSLL-P
LGPCCLPSPTPSFQPL----ATRSLQPKAKTWQTQPPELR--------------------
------------------------------------------------------------
-------------------------TSRP-ATQLD--STSAE----TSLV-PSSRSSKSR
VSIPMVRILAPVLVLLSLLL----T--A------GLAALSRYLLRR-RK--EAQLAAET-
-QRM----------EKVHL-----------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MTLSRA-------LLLLCL-----------------------------------
-------PG

PF07686 // ENSGT00470000042273_0_Domain_0 (190, 348)

CLS---L-----------TGPG-SVSG------TVGGSLSVQCRYDAKYKG
Y-NKYWCRG---QHD------TSCT-HIVET-GGEER--ERRNGRVSIRDQASSLTFTVT
MEDLRADDAGHYWCRIQTIWIFDEW-------SRDPSV-A--VMV--FVSPXXXXXXXXX
XXXX--------------------------------------------------------
--------------XX-----------XXX---XXX----------------------X-
-------X--------------------------X--XLGSEG----LPILSC-------
--RF--GSHFVLLVCLKL-----PLLLI------MLSAVL-WVNRPQRA--PG--GR---
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
--HANRLRKQKW-------ARLLW------------------------------------
----V--SGCLS--

PF07686 // ENSGT00470000042273_0_Domain_0 (195, 318)

-L-----------SGPS-RVTG------IVGRSLSVECRYQKKFIS
N-NKYWCKP---FCL-----LS-PK--IVET-TESQR--EVTRGRVSIRDRPANLTFTVT
LKSLREEDAGTYECGINVPV------------SIDPTF-E--VEV--SVIPAPS-ASP-T
PR-P--------------------------------------------------------
---------I--PPTVAA-K---------V---STVSFTTLTT---------------E-
-------SAT---H-----SASSQEEYEPTQNW---------------------------
-RLH---------ALLIS-LALLLLLLG------GFSLLA-WRMVQR--RAKA--GEKPE
LPQS---------RSQ-----AAEQT-----EPSYA------NLELQT-----WP-----
---LSGK--PVQPTRAE-VEYSTVG----------------------PP------SDDLH
YTSIVFD--SRSQDSKADRIPS------ET---------P--VYSVVKKT----------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MWLPWA-------LLLLW------------------------------------
----V--PGCFA---P-----------SDRR

PF07686 // ENSGT00470000042273_0_Domain_0 (212, 318)

-TVAG------PVGGSLRVQCRYEEAHRT
L-NKYWCRP---PQI-----FL-CD-KIVET-KGSAR--K-RNGRVSIRDSPANLSFTVT
LENLTEEDAGTYWCGVD

ENSGT00470000042273_0_Linker_0_1 (318, 554)

TPWLRDF---------HDPVV-E--VEV--SVFPAST-SMTPA
SITA--------------------------------------------------------
---------A-KTSTITT-A---------F---PPVSSTTLFA---------------V-
-------GAT---H-----SASIQEENEEVVN----------------------------
SQLP---------

PF15330 // ENSGT00470000042273_0_Domain_1 (554, 730)

LLLSL-LALLLLLLV------GASLLA-WRMFQK--WIKA--GDHSE
LSQN---------PKQ-----AAKQS-----ELHYA------NLELLM-----RP-----
---LQEK--PAPPREVE-VEYSTVA----------------------SP------REELH
YASVVFD--S-----NTNRIAA------QRPRE----EEQDSDYSVIRKT----------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MQLLVL----------LWGCLLL-------------------------------
-------PGYE--------------ALE

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 319)

GPK-EISG------FEGDTVSLQCIYREELRD
H-RKYWCRK---GGILF----ARCS-GTIYA-GEEGQ--ETTEGRVSIRDSRQELSLIVT
LWNLTLQDAGKYWCGVEKRGP-------------DESL-L--ISL--FVFPG--------
--PCCPPSPSPTFQPL----ATTRLQPKAKAQQAQPPG--LTSPGLYPAITTAKQGKTGA
EATPFSGTSQYG---------------------------HERTS-------QYTGT-SP-
-----Q-AATS-PPA----G-----SSRP-PMQLD--STSAED---ASPA-LSSGSSKPR
VSIPTVRILAPVLVLLSLLS----A--A------GLIAFGSHLLLW-RK--EAQQATET-
-QRN----------EKVCLS---HLT----------------------------------
-------------------------------------------------------TEEKE
--APSQA-------PEGDVISM----PPLHTSEE---ELGFSKFVSV-------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MWALIL----------VWGCLLL-------------------------------
-------PGYG--------------AMVG

PF07686 // ENSGT00470000042273_0_Domain_0 (210, 319)

PK-EISG------FEGDTVSLQCTYQEELRT
H-QKYWCKQ---GGFLL----SRCS-NTIYA-GEDGQ--ETTEGRVSIQDSPQTLTLHVT
LRKLTLQDSGKYYCGVSKLGR-------------DESV-L--VSL--LVFP---------
-GPCCPLSPTPSFQPL----TTRSFQPKAKAWQTQPPELR--------------------
------------------------------------------------------------
-------------------------TSRP-PTQPD--FTSAED---TPLS-PSSSSSVSS
VSIPTVRILAPVFVLLALLL----A--A------GLAALGSCVLRW-RK--EVHLATET-
-QRN----------GKVHLS---H------LPLEYT------VINLAGP-----PG----
---PQASP----SPCTE-TQGLSQT------------------------------SEEDE
--APSQD-------PERDMIPE----PPLHMSGE---ELGFSKFISV-------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
--------------------MNLCF----PG-----------------------------
---------CLT---V-----------SG

PF07686 // ENSGT00470000042273_0_Domain_0 (210, 318)

PS-TVMG------TMGESLSVQCQYEEKYKT
F-NKYWCRQ---PCL-----P-IWH-EMVET-RGSER--MVRSDRVVITDHPGDLTFTVT
LENLTADDAGKYRCGIATILQEDGL----SGFLPDPFF-Q--VQV--LVSSAS-------
------------------------------------------------------------
---------STENSVKTP-G---------S---P--------------------------
---------------------------------------------------TR-PSQCEG
SLPS--CAYFLLLPLLKV-----PLLLS------ILGAIL-WVNRPWGT--PW--T----
-----------------------ESM-----NRRTC------H--TPCPL--EPC-----
---P-----ETQP-----------------------------------------------
-----L------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------VN---Y------------------------------------
----I--TGYDLIRSLNAEIR--EDP

PF07686 // ENSGT00470000042273_0_Domain_0 (207, 336)

ITGPG-AVSG------PEGGSLTVQCCYNPEWRT
H-KKWWCRG---AD--W----GPCK-ILVET-TGTEE--EVKKDRVSIRDSWKDYTFNVT
MEALRRDDADTYWCGIERTGI-------------DKGV-Q--VKV--TIDPDFCDSSDE-
------------------------------------------------------------
-------------------------------------------S-----------D-SP-
-------VSLG-SHM---------EAKCR------------------------VLGITRL
SILL--PLIFAIVLLLLV-----AI-----------SLLA-WRVMKKQK--KA--SGVS-
-------------PEQ------ALQPLEG--EICYA------NLTLQQNG--ASSN-FSR
KKASVKPPSASQ---VE-VEYVTMHP---------------------VP------RQEVS
YASLSFGI-LDQEPTYSNTGQH-TTHVSGGSHQ----ELT--EYSTVRRP----------
----------------------

------------------------------------------------------------
------------------------------------------------------------
-----MPLLM-L-Y--PLLF---W------------------------------------
----L--SGY---------SI--ATDI

PF07686 // ENSGT00470000042273_0_Domain_0 (208, 319)

SGPM-TVNG------PERGSLMVQCIYNSGWET
Y-LKWWCRG---AI--W----HDCK-ILVKT-TRSEQ--EVKRDRVSIKDNQKNHTFTVT
MEDLMQTDADTYWCGIERTGT-------------DLGV-K--VQV--IIDPA--------
------------------------------------------------------------
------------------------------------PVTPEETS-----------N-SP-
-------TLTG-HHL---------DK---------------------------RHNLLKL
SVLL--PLIFTILLLLLV-----AA-----------SLLA-WRIMKCQQ--KA--VGMS-
-------------PEQ------VLQPLEG--DLCYA------DLTVQLTR--TSP-----
QKATTKLSFSAQADQVE-VEYVAMAP---------------------FP------KEDIS
YASLTLAA-EDQEPTYCNMGPL-SSHIPSGGPE----DPT--EYSIIRRP----------
----------------------

------------------------------------------------------------
-----------------------------------------------------------M
TPGVTGVWLPSA-------LLLLQV-----------------------------------
-------PGCVP---L-----------H

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 324)

GPS-KVTG------TVGESLSVRCQYEEEHKT
N-DKYWCRVTM---L-----P--CK-GLVKT-RASK---EAGKGRVSIRDHPATLTFTVT
LENLTLEDAGTYKCGVDIGE--DMEWRSL---------------G--QSVFPS-FAPV--
----------------------------------------------------TGS-----
---------SPENRANTL-G---------S---PT--SSPVHT---------------Q-
-------PS----------------------VT-------------TEDTTPG-PSLQP-
-VLS--SIYFKVLVFLEV-----PLLLS------MLSAVL-WVNRPQRC--SG--K----
-----------------------KQH-----CPDYE------NQ----------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MRLLVL----------LWGCLLL-------------------------------
-------PGYE--------------ALE

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 319)

GPK-EISG------FEGDTVSLQCTYREELRD
H-RKYWCRK---GGFLL----SRCS-GTIYA-GEEGQ--ETTKGRVSIRDSHQELSLIVT
LWNLTLQDAGKYWCGVDKRGL-------------DESL-L--ISL--FVFPG--------
--S---------------------------------------------------------
------------------------------------------------------------
--------------------------SRP-PMQLD--STSAED---TSPA-LSSGSSKPR
VSIPMVRILAPVLVLLSLLS----A--A------GLIAFSSHLLLW-RK--EAQRATET-
-QRN----------EKVCLS---HLNHRTSELDPDE------ASEIS--------S----
---PTFI-----------------------------------------------------
---------------------------------------------SV-------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MWLSPA-L--LLLI----------------------------------------
----L--PGY--------SIA---AKIT

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 349)

GPT-TVNG------SEQGSLTVQCAYGSGWET
Y-LKWWCQG---AD--W----NYCN-ILVKT-NGSEK--EVKKNRVSIRDNQKNHMFTVT
MENLKRDDADSYWCGIERPGI-------------DLGV-K--VQV--TINPGTQTAVPEW
TTTTASLAFT----AA--------------------------------------------
------------------------------------------------------------
-------------------------------------------------ATQKTSSPLTG
SLLS--STHFLFLFLLEL-----PLLLS------MLGTVL-WVNRPQRR--S--------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MWLSQA-L--LLLI----------------------------------------
----L--AGY--------SIA---TEIT

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 348)

GPA-TVNG------LEWGSLTVQCAYSSGWET
Y-LKWWCRG---AD--W----NGCN-ILVRT-NGSEQ--EVKKNRVSIRDNQKNRIFTVT
MENLKRDDADSYWCGIEKTGI-------------DLGV-N--VQV--TIKPDTKTPVLEW
TTATGSLAFT----PA--------------------------------------------
------------------------------------------------------------
-------------------------------------------------ATQ-TSSPLTR
SLLS--STHFLFLLFLEL-----PLLLG------MLGAVL-WVNRPQRR--S--------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
----------------MGKTLTGNLNNRRGQLGSPA--L---WNPAGIWIFCWLWVKGVE
WEGEAMWRLSSA-L--LLLS----------------------------------------
----F--PGCF--------------SI

PF07686 // ENSGT00470000042273_0_Domain_0 (208, 349)

QGPA-SVRG------PENGSVTIRCRYSSRWQM
Y-NKYWCRG---AD--W----STCR-VLIRT-RGSEK--EKKSGRLSLRDNWRDNSLLVT
MEMLTQNDTDTYWCGIEKFGT-------------DRGT-R--IKV--TVYSEGKDTMSSK
-MLSTM------------------------------------------------------
----------------------------------------------------------P-
-------TM------------------------------------------DSNAYVMSS
DLHK--RTHYLLLVFVKV-----PVLLI------LAGVVL-WLKGSTQK--VS--EEEW-
-----------------------RHTFCS--NLDSEL--TVKDIAP--------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
-------------M--RLFPVLLWI-----------------------------------
---LF--PGCQAVL

PF07686 // ENSGT00470000042273_0_Domain_0 (195, 349)

VV-----------TGPR-AVRG------QPGGLVTVRCQYNRGFEA
L-PKFWCGG---RT--WHC---SNG-RIVET-TGSQA--VVKQGRVSIRDNHTQRVFTVT
MENLTLADAGTYQCGVLKTG------------HPDPRN-S--VKV--IVSSGLTKQPDAP
SS----------------------------------------------------------
------------------------------------------------------------
----------------------------------L----------N--TDLNFSPTTVIN
DTRF--IILFLLLLLLKG-L---IFLS-------IIGATI-WVSMLYQ------------
-SSC---------REM-----KPDGQA-H-------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MRPLLM----------LWGCLVL-------------------------------
-------PGYG--------------SVVD

PF07686 // ENSGT00470000042273_0_Domain_0 (210, 335)

PK-EISG------FEGDTVSLQCTYGEELKK
H-QKYWCRE---AGLFI----SRCA-GTVFS-GEYGQ-----EGRVSVHDNPRENRFTVI
LRNLTLKDMGKYWCGVKKLGF-------------DKTM-S--VSL--LVFPG--------
------------------------------------------------------------
-------------------------------------------------TSLHPAT----
----------S-PPA----GIS-----QP-ATQLD--STSTED---TSFV-PSS-SSKSR
VSVPLIRILAPVLVLLALLL----A--T------GLAALGSCMFQW-RE--KAQLASET-
-QKK----------DNVHLS---HLT----------------------------------
-------------------------------------------------------SEDDE
--ASWRD-------HKGDMTPA----STLPMSGD---EPGFSKFSSV-------------
----------------------

-----------------------------------RHTKNRTEQCPQSLSPEQQQMHR-D
GSARLSP-------------------------------------------LALS--PKPQ
CG-------GLL-------AGAFRP----FR-----------------------------
---------SLS--

PF07686 // ENSGT00470000042273_0_Domain_0 (195, 318)

-L-----------SGPS-TVTG------AVGESLSVECRYEEEYRA
F-HKYWCRQ---PCF-----P-LWQ-RTVQT-SGPEV--EVKSGRVSITDHPEDLAFTVT
LESLTADDAGKYRCGVATILKEEGL----LSFLPDPFF-Q--VQV--IVSPGASQEF---
------------------------------------------------------------
---------SASGRGTGA-G---------V---CV-S----EL---------------Q-
-------GQVH--------------------CV-------------HVSVCLV-TASSHR
PLLG--STHFLLLVFLKV-----PLLLG------MLGAVL-WVNRPQRA--VC--G----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MWLPWA-------LLLLW------------------------------------
----V--PGCFA---P-----------SDRR

PF07686 // ENSGT00470000042273_0_Domain_0 (212, 318)

-TVAG------PVGGSLRVQCRYEEAHRT
L-NKYWCRP---PQI-----FL-CD-KIVET-KGSAR--K-RNGRVSIRDSPANLSFTVT
LENLTEEDAGTYWCGVD

ENSGT00470000042273_0_Linker_0_1 (318, 554)

TPWLRDF---------HDPVV-E--VEV--SVFPAST-SMTPA
SITA--------------------------------------------------------
---------A-KTSTITT-A---------F---PPVSSTTLFA---------------V-
-------GAT---H-----SASIQEENEEVVN----------------------------
SQLP---------

PF15330 // ENSGT00470000042273_0_Domain_1 (554, 730)

LLLSL-LALLLLLLV------GASLLA-WRMFQK--WIKA--GDHSE
LSQN---------PKQ-----AAKQS-----ELHYA------NLELLM-----WP-----
---LQEK--PAPPREVE-VEYSTVA----------------------SP------REELH
YASVVFD--S-----NTNRIAA------QRPRE----EEQDSDYSVIRKT----------
----------------------

------------------------------------------------------------
--------------------MTQFL------------------LISR-FPGPN---VAER
SQGVRTMWLPAT-------LLLLCL-----------------------------------
-------PG

PF07686 // ENSGT00470000042273_0_Domain_0 (190, 344)

CLS---L-----------TGPG-SVSG------ITGSSVTVQCRYAKAYKG
Y-TKYWCRG---QYD------TACD-RIVET-NGNEQ--EVRNGRVTIRDHAHNLTLMVT
MENLNIDDAGSYWCKIRTVWILDVF-------SRDPAV-Q--VKV--SVSPVFLAPMRTT
PLGE--------------------------------------------------------
--------------VP--------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MHLLML-F--FLLF---W------------------------------------
----L--AGN--------STA--KSQIT

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 319)

GPG-TVSG------PERGLLTVKCCYDPKWKT
H-KKWWCRG---AD--W----NSCE-ILVQT-NGSEN--EVKKGRVSIRDDQENLTFTVT
MENLRRDDADTYWCGIER

ENSGT00470000042273_0_Linker_0_1 (319, 542)

FGT-------------DPGV-I--VEV--TIDPVSTAIPMTS
--------------TSTST-------------------------------T---------
---------------SM----------------STAPVTLEESN-----------N-SQ-
-------IITS-YHF------------SG------------------------RQNPMKL
T

PF15330 // ENSGT00470000042273_0_Domain_1 (542, 732)

ILL--PLIFAVLLLLLV-----VV-----------SILA-WRMAKHQK--KE--TGIS-
-------------PEQ------VLQPLEG--EICYA------NLTLQQTG--STPG-SSQ
KKASTRPSSSVQDNQET-VEYVTMAP---------------------FP------REDIS
YASLSLDA-GDQEQTYCNTGHH-IAHIPDRVPE----EST--EYSTIRRP----------
----------------------

------------------------------------------------------------
-----------------------------------------------------------M
RRPDQAVWLPLA-------LLLLW------------------------------------
----V--PGCSS---I-----------S

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 316)

GPT-SMTG------TLGSSLIVQCSYEEQLRT
H-FKYWCKK---PC--------FWK--TVET-KQSSK--EVRNGRVSIRDHPANLTFIVT
LENLTEDDAGTYRCGIDTSWLGGY--------LQDPAV-H--IVV--SVIPATT-SAPPA
NITV--------------------------------------------------------
---------TQ-ISTITA-GIT-----TTS---SSSSPTVPIT---------------M-
-------GAT---H-----SASSQEEFQQSQ---G-------------------------
VGLQ---------VLLSL-LALLLLLLG------GSLFLA-WRIVRK--RVKA--GENPK
PLRT---------HSQ-----NTLQG-----ELYYA------NLELQT-----RT-----
---LQGE--PTQPRQEE-VEYSTVKK---------------------PS------LEELH
YSLVAFD--PESQDSKANRIPS------RRTLE----QEP--EYSVIKKT----------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------

PF07686 // ENSGT00470000042273_0_Domain_0 (190, 348)

YR--------------ALQGPK-EVTG------LEGNSVSVQCTYGDELRA
H-SKYWCRE---AGMFL----SRCS-GTIHA-AKDGS--ETTEGRVSIRDSPEERLFTVT
LRALTPTDTGEYWCGARTLRS-------------HKFF-R--VFV--RVIPXXXXXXXXX
XXXXX----------------XXXXXXXXXXXXXXXXXXXXXSAGLHPTVATTKQGNGAA
KTSSIAGTSLYG---------------------------QAASTP-YPGTSLPTRF-PI-
--------------------------------QAG--S--AP-----------GTQAPLC
VTIPTARMLSPFLVLLSLLL----A--A------GLIALGSHMLGC-GK--EAPPVSET-
-XXX----------XXXXXX---XXA----------------------------------
-------------------------------------------------------PEEVT
--TPSQF-------AEEDRITG----DPPCTPEE---QQAFSKFVSV-------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MWLPWA-------LLLLW------------------------------------
----V--PGCFA---L-----------R

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 319)

GPG-TVDG------HVGGSLSVQCHYEEEHKT
L-NKYWCRP---PRV-----LR-CD-KIVET-KGPAG--K-MNGRVSIRDCPANLSFTVT
LENLTEEDAGTYWCGVDT

ENSGT00470000042273_0_Linker_0_1 (319, 554)

PWLRDF---------HDPVV-Q--VEV--SMFPASM-SMTPT
SITA--------------------------------------------------------
---------A-KTSTITT-A---------F---PPVSSTSLFA---------------V-
-------SAT---H-----STSNQEENEEVVS----------------------------
SQLP---------

PF15330 // ENSGT00470000042273_0_Domain_1 (554, 730)

LLLSL-LALLLLLLM------GASLLA-WRMFQK--WIKA--GEHSE
LSQN---------PKQ-----AAKQS-----ELHYA------NLELLS-----WP-----
---LQEE--PAPPREAQ-VEYSTVA----------------------AP------REELH
YASVVFD--S-----NTNRIAA------QRPQE----KEPDSYYSVIKKT----------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MWLPWA-------LLLLW------------------------------------
----V--PGCFA---L-----------RG

PF07686 // ENSGT00470000042273_0_Domain_0 (210, 323)

PG-TMAG------PVGGSLSVQCWYEEKHKT
L-NKYWCRP---PRV-----LR-CD-KIVET-KGPAG--E-MNGRVSIRDCPQNLSFTVT
LENLTEEDAGIYWCGVDTPLLQ

ENSGT00470000042273_0_Linker_0_1 (323, 554)

DF---------HDPYV-Q--VEV--SVFPAST-SMTPT
SITA--------------------------------------------------------
---------A-KTSTITT-A---------F---PPVSSTSLFT---------------V-
-------SAT---H-----STSNREENEEVVS----------------------------
SQLP---------

PF15330 // ENSGT00470000042273_0_Domain_1 (554, 730)

LLLSL-LALLLLLLM------GASMLA-WRMFQK--RIKA--GEHSE
LSQN---------PKQ-----AAEQS-----ELYYT------NLELLS-----WP-----
---LQEE--PAPPREVQ-VEYSTVA----------------------AP------REELH
YASVVFD--S-----NTNRIAA------QRPRE----KEPDSHYSVIKKT----------
----------------------

------------------------------------------------------------
-------------------------MHRRCKPELRQNF----QSASGIRICHWLQIRWMR
SREGRAMWLSPA-L--LLLS----------------------------------------
----L--SGCF--------------SIRG

PF07686 // ENSGT00470000042273_0_Domain_0 (210, 349)

PV-SVRG------PEKGSVKVQCQYKRGWET
H-VKWWCRG---AR--W----VSCE-ILIQT-RGSEQ--EEKKDLVSIKDSHTDCTFTVT
MEGLRQNDSNIYWCGIQRLGP-------------DLGT-Q--VQL--TVDPEGAASAPAS
S-----------------------------------------------------------
------------------------------------------------------------
--------S------------------------------------------VNSNIRVSI
STHK--RNHYMLLVFVKV-----PILLI------LVGAIL-WLKGS-QR--VP--EEPG-
-----------------------DQPIYM--NFS-EL--LTKDMAA--------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MWLSPA-L--LLLS----------------------------------------
----F--PGCL--------------SI

PF07686 // ENSGT00470000042273_0_Domain_0 (208, 345)

QGPE-LVRG------PEQGSVTVQCHYSSRWQT
N-RKWWCRG---AH--W----STCR-ILIRT-TGSEK--EMKSGRLSIRDNQKNNSFQVT
MEMLKQNDTDTYWCGIEKFGT-------------DRGT-R--VKV--IVYS-GKATMSTS
KQ-LSW------------------------------------------------------
----------------------------------------------------------P-
-------TV------------------------------------------DSRADMASS
DLQK--RTHYMLLVFVKV-----PVLLI------LAGVVL-WLKQSTQK--VP--EEEW-
-----------------------RHTLCS--NLDSVP--LAKDISP--------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
-----------------------------------------------------------M
SPWALAVWLPLN-------LLLLW------------------------------------
----L--PGCCL---L-----------R

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 316)

GPS-RVTG------TQGGSLSLQCWYEEKYKT
Y-NKYWCRS---SSV-----LGRCE-NTVKT-KDSER--EVSRGRMSISDHPENLTFTVT
FKNLSLEDSGSYWCG

ENSGT00470000042273_0_Linker_0_1 (316, 555)

IHIPWH----------EGPDDSF-L--VSV--SVLPYEP----PS
Y-----------------------------------------------------------
----------------QP-G---------A---PTVPPTSPAE---------------N-
-------RPT---Q-----GSSSQGNNHKG--Q-G-------------------------
PKLV----SWGLLT

PF15330 // ENSGT00470000042273_0_Domain_1 (555, 733)

LLSL-LMLLLLLFV------ATALLV-CRMLQR-R-VKA--REPPD
LSQN---------LRQ-----AAEPS-----EPQYA------NLQLHT-----WA-----
---LREG--PAPPRPAE-VEYSTVAC---------------------PT------TEDLH
YSSVVFN--AEKQDSNTKR------------PQ----EEA--EYSMIQEPGK--------
----------------------

------------------------------------------------------------
------------------------------------------------------------
-------THLAT-L--VMNL---C------------------------------------
----F--PGF--------SAA--WKDIT

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 340)

GPE-TVSG------LERGSLTVQCRYTSMWKT
Y-TKWWCRG---AV--W----SSCR-ILIKT-NGSEK--EVKEERLSIRDYQKNLMFSVT
MEDLRGDDADGYWCGIERTGS-------------DLGV-

ENSGT00470000042273_0_Linker_0_1 (340, 542)

Q--VKV--TIDPAPTTVPTTV
PTT----APT----TSVST-------------------------------M---------
---------------NT----------------FTAPATTEETR-----------S-LL-
-------TPTN-SYH---------STRSHA---------------------AVLSGSIDL
R

PF15330 // ENSGT00470000042273_0_Domain_1 (542, 732)

VLL--PLIFAVLLLVLV-----AA-----------SLLA-WRMMK------G--ERAW-
-----P-----YEPSE------VRVPVEG--DLCYA------NLSMHQPG--T-----SW
QKPSTKS-SSAQANQGE-VECVIMAP---------------------FP------REEIS
YASLCLDI-LDQEPTYSNTD-----HTPSRAYE----EST--EYTSIRRP----------
----------------------

------------------------------------------------------------
----------------------------------------------------------MT
QRAG-AAMLPSA-------LLLLCV----PG-----------------------------
---------CLT---V-----------S

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 318)

GPS-TVMG------AVGESLSVQCRYEGKYKT
F-NKYWCRQ---PCL-----P-IWH-EMVET-GGSEG--VVRSDRVIITDHPGDLTFTVT
LENLTADDAGKYRCGIATILQEDGL----SGFLPDPFF-Q--VQV--LVSSAS-------
------------------------------------------------------------
---------STENSVKTP-A---------S---P--------------------------
---------------------------------------------------TR-PSQCQG
SLPS--NTCFLLLPLLKV-----PLLLS------ILGATL-WVNRPWRT--PW--T----
-----------------------ES-----------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
-----------------------------------------------------------M
TARAWASWRSSV-------LLLLLV-----------------------------------
-------PGYFP---L-----------SH

PF07686 // ENSGT00470000042273_0_Domain_0 (210, 318)

PR-TVAG------PVGGSLSVQCHYEKEHRT
L-NKFWCRP---PQI-----F-LCD-KIVET-KGSAG--K-RNG-VSIRDSPANLSFTVT
LENLTEEDAGTYWCGVDTPWLRD--------F-HDPVV-E--VEV--SVFPAGTT-----
----------------------------------------------------TAS-----
---------SPQSSMGTS-G---------P---PT--KLPVHT---------------W-
-------P-----------------------SV-------------TRKDSPE-PSPHPG
SLFS--NVRFLLLVLLEL-----PLLLS------MLGAVL-WVNRPQRS--SR--S----
-----------------------RQN-----WPEGE------NQ----------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MWLSPA-L--LLLI----------------------------------------
----L--PGY--------SIA---AKIT

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 348)

GPT-TVNG------SERGSLTVQCAYGSGWET
Y-LKWWCQG---AD--W----NYCN-ILVKT-NGSEQ--EVKKNRVSIRDNQKNHMFTVT
MENLKRDDADSYWCGTERPGI-------------DLGV-K--VQV--TINPGTQTAVPEW
TTTTASLDFT----AA--------------------------------------------
------------------------------------------------------------
-------------------------------------------------ATQKTSSPLTR
SPLK--STHFLFLFLLEL-----PLLLS------MLGTVL-WVNRPQRR--S--------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MWLLPA-------LLLLCL-----------------------------------
-------SGCLS---L-----------T

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 316)

GPG-SVTG------TAGGSLTVWCQYESMYKG
Y-NKYWCRG---QYD------TSCE-SIVET-KGEEK--LERNGRVSIRDHPEALAFTVT
MQNLNEDDAGSYWCKIQTVWVLDSW-------SRDPSD-L--VRV--YVSPAITTPR-RT
THPA--------------------------------------------------------
--------------TP-----------PIF---LVVNPG---------------------
----------------------------------R--NLSTG------EVL----TQNSG
FRLS--SPHFLLVVLLKL-----PLLLS------MLGAVF-WVNRP-WA--PA--GRY--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------TRRRRQSF-----KHPGIPVCHLWQ--RVR
SQGSWAMWLPSA-L--LFLS----------------------------------------
----L--PG

PF07686 // ENSGT00470000042273_0_Domain_0 (190, 348)

CF--------------TIRGPT-SVSG------TELGSVTVQCDYDAGWET
N-RKWWCRG---KS--W----G-CK-VLIRS-TGTEQ--EVKAGRVSIKDNHRSHFFTVT
MDKLRRDDANTYWCGIAKSGT-------------DLGV-Q--VQV--TVGS---------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------THYVLLAFVKV-----PFLLV------VLGVIL-WLKGS-QR--AP--KEQR-
-----------------------GQPDNA--DFSTDR--LAKGTAPC-------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MQGLVL----------LWACLVL-------------------------------
-------PGNG--------------AMK

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 320)

GPK-EISG------FEGDTLAVRCTYSQEWIK
H-GKYWCKQ---GGLLI----SRCS-NTIYT-R-GDQ--EVTQDRLSIRDSPQELAFTVT
VKHLTLEDTGKYWCGVNILGP-------------DKIF-E--VTL--IVFPGNRDSAS-T
TGHCCPP-PTPSFQPLTAVPSLQRPQPKSKGWRTQPPE--LMSSDLRLTNTTVKQGKTGI
EATPSTGVAPKW---------------------------PATPSP-YPGTSPQAET-SP-
-----H-TTTS-PHA----GSS-----HP-AILVD--STTAED---TNPV-PSSSRSKHS
VTIPMVRKLAPVLVILSLLL----A--T------GLIAFGSCIFQWRKK--G-----ET-
-GCS----------DKCLL-----QALGNGWVPEDA------MISLAGP-----IR----
---PDDKPEPSASPCKE-IQSLRQT------------------------------TEEEE
A--PSED-------PKGNMILA----PPLQMSQE---ELDFSEFIPV-------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MHRLLL-L--PLFF---C------------------------------------
----L--SGS-------------

PF07686 // ENSGT00470000042273_0_Domain_0 (204, 348)

-SAIWGPS-NVSG------PEGGSLSVLCGYDATFKT
Y-NKWWCRG---AV--W----RPCQ-ILVQT-TGSEQ--EVKKDRVSIRDNHKNLTFTVT
MEKLRKDDADVYWCGIQRTGT-------------DDGV-Q--MTV--SVDPXXXXXXXXX
XXX---------------------------------------------------------
-------------------------------------------------------X--X-
-------XXX---XX------------------------------------XXXXXXXXX
XXXX--XXXCAGFLLLLV-----GA-----------SLVV-WRMMKLQK--KX--XXXXX
XXXXXXXXXX----------------------XXXX------XXXXX-------XX-XXX
XXXXXXXXXXXXXXXXX-XXXXXXDP---------------------FP------KEEVC
YASLSMNA-SDQELIYSNMYPG---GPRSLSQE----EPT--EYSAIKRA----------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MRPLVL----------LWGCLVL-------------------------------
-------PGYE--------------AL

PF07686 // ENSGT00470000042273_0_Domain_0 (208, 319)

QGPK-EISG------FEGDTVSLQCTYSEELRA
Y-KKYWCRQ---AGFLL----LRCS-GIIYA-GEEGQ--ETTQGRVSIRDRPQELALTVT
LRNLTLQDAGKYWCGVKKLGF-------------DESF-L--VSL--LVFQG--------
--PCCPPSPTPSFQPL----ATRSPKPKAKAWQTQPPE--PTSPGRYPTVTTAKQGKTGA
QASPVTGTSPYG---------------------------HAGPS-------LHTGT-SP-
-----H-AATS-PHA----GSS-----RP-TMQLD--STRAKD---TRSV-PSRSISKSR
VSIPLVRMLAPVLVLFGLLL----A--T------GLIGLGSRMLRR-RK--QAQLAVET-
-QRN----------EKVYPS---HLTT---------------------------------
--------------------------------------------------------EEEE
--PPSQD-------LEGDMIPV----PPFHMSEE---DLGFSKFISV-------------
----------------------

------------------------------------------------------------
-----------------------------------------------------------M
TARAWSSWWPSA-------LLLLLV-----------------------------------
-------PGCFA---L-----------SG

PF07686 // ENSGT00470000042273_0_Domain_0 (210, 318)

PS-TVAG------PVGGSLSVQCGYEEEHRR
L-NKYWCRA---RWT-----I-GCV-TIVET-RGSAG--KVRNGRVSIRDHPTNLSFTVT
LKNLTEDDAGTYWCGVDTPWLRD--------L-EDPVI-E--VEV--AVFPALTT-----
----------------------------------------------------TAS-----
---------SPQSSTGTW-G---------P---PT--KLLVHT---------------W-
-------P-----------------------IP-------------TREDSPD-PSPQPG
SLLS--SPHFLLLVFLKL-----PLLLS------MLGTVL-WVNRPQRS--SR--S----
-----------------------RQS-----QPDGE------NQ----------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MWLPSA-------LLLLSV----PG-----------------------------
---------FSS---L-----------S

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 316)

GPS-TVTG------IEGGSLSVQCWYEEKYKA
F-TKYWCRQ---PCL-----L-LWN-QMVET-RGSEG--EVRSGRVSIMDHSADFAFTVT
LENLTTDDAGKYRCGIATILREEGL----NGFLPDLFF-Q--VQV--FVSPRSL------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--PD--RVHFLLLIFLKV-----PLLLI------MLSAVL-WVNRPQWA--IC--G----
-----------------------KHS-----QPDDD------GLQPSLPI--DIL-----
---SRDI--TVQTTEGG-TSA------------------------------------PKL
YFSSHFI--AK------NL-----------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------IT

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 320)

GPD-TVSG------QQQGSLTVQCRYDSSWKK
H-KKYWCQG---AD--W----STCE-ILLKT-NASEQ--LVKKDRVSIRDDQTGFIVTVT
MEDLRISDAGIYWCGIERSGR-------------DLHF-E--VNV--NIDPVS-------
---I--------------------------------------------------------
-----------------------------------------------------MAP-VL-
-------TTTA-STME------NTGN---------------Y--------GGTQTNTHTW
SLLS--SIYFKLLVFLEV-----PLLLG------MLSAVL-WVNRPQRY----------G
LVKD-----QS-----------------S--DAQ--------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MWLPSA-------LLFLCL-----------------------------------
-------PGCLS---L-----------T

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 318)

GPG-YVTG------IEGTTLRVQCQYAEGYKG
Y-KKYWCRG---EYD------IECK-SIVET-EGGDA--VKRNGRVSIRDYENDLTLTVT
IEDLQQYDAGTYWCKIQTSWIFDSW-------SRDPLE-Q--VKV--YVIQA--------
------------------------------------------------------------
--------------TTTT-RIPLTT--PAL---PLVITR---------------------
----------------------------------Q--NIRTE-------VS----TLYPR
SLLS--SLHFLLLVFLKL-----PLFLS------MLGAVF-WVNRPQRT--AG--ERVSL
SRSP---------A--------VHRPR-R--ALCPD------A-ALQT------------
-----GL-----DK--S-LVLERLA----------------------GRQR---------
------------------------------------------------------------
----------------------

------------------------------------------------------------
---------------------------------------------------LWWR-----
-------ETPPQLL--PRFC----------------------------------------
----F--PGCF--------------S

PF07686 // ENSGT00470000042273_0_Domain_0 (207, 345)

IKGPE-SVRG------LEGGSVSVQCQYTPGWEN
Y-KKWWCRG---AE--W----ESCH-NLVET-DGSEQ--EKKVDRVSIRDNQSHLLFTVT
MEEVRQSDTDTYWCGINRSGP-------------DLGA-S--IKV--TIDPVDMVLSTLA
SP---RS-----------------------------------------------------
--------------------------------------R-------------------T-
--------T------------------------------------------TSRRTEGTS
DSYI--RNHYILLVFLKA-----PVLLM------LVVAVL-WLKGS-QQ--RL-------
-------------------------SVYR--NLSSDL--VGDTAP---------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
-----------------------------------------------------------M
IPRVMAVWLPSS-------LLLLQV-----------------------------------
-------PGCVP---L-----------R

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 348)

GPS-SMTG------TVGESLRVQCQYEEKHKA
Y-SKYWCRVSR---L-----R-SCQ-NTVKT-RASK---EARNGRVSIRDDPATLTFTVT
LDNLTLEDADTYMCGITP------------SLGIDSYS-K--VVV--SVVPASAAVT---
-----------------------------------------------------GS-----
---------VPENRTNTL-G---------S---LT--SSLVHT---------------Q-
-------PS----------------------VT-------------TEDTTPG-PSPHPR
SLLS--SIYFQLLVFLEV-----PLLLS------MLSAVL-WVNRPQGC--SG--E----
-----------------------KRH-----CPDYE------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
-----------------------------------------------------------M
TPGDGRPWLPAA-------LLLLQV-----------------------------------
-------PGCWS---L-----------

PF07686 // ENSGT00470000042273_0_Domain_0 (208, 319)

RGPT-SVMS------TVGGSVSVQCQYEEEFRE
N-DKYWCKS---PCV--------WS-LV-KT-KGADR--EVRKGRVSIRDHPANLTFTVT
LENLTEDDAGTYKCGIDTSVLQG--------YFRDR------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
-----------------------------------------------------------M
TPGDGRLWLPAA-------LLLLQV-----------------------------------
-------PGCSC---L----------

PF07686 // ENSGT00470000042273_0_Domain_0 (207, 322)

-SGPT-SVTG------TVGGSLSVQCQYEEEFTE
N-VKYWCKS---PCL--------GD-IV-VT-KEADI--EVRSGRVSIRDHPANLTFTVT
LENLTESDTGTYRCGIDTSLLPE--------YLLDLNF-R--VVL--SVTPGLHWTL---
-----------------------------------------------------PD-----
---------P--T-QKTA-T---------S---QE---SPSSR---------------Q-
-------H-----------------PGSS-PRS-------------HPIEDQA-SKGEER
SLLS--SIYFQLLVFLEV-----PLILS------MLSAVL--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
-----------------------------------------------------------M
TQEDWALWLPSA-------LLLLW------------------------------------
----V--PG

PF07686 // ENSGT00470000042273_0_Domain_0 (190, 348)

CLM---L-----------SGPS-TVTG------IVGESLSVQCRYEEKFKE
S-NKYWCRE---PAL-----RP-CY-KIVET-SGSER--EKRRRRVSISDHPAQLSFTVT
MTNLTVEDAGKYWCGIDITWLRDAL------LPFDPTF-Q--VVV--SVSPAPA----RM
SSTP--------------------------------------------------------
---------T-STT--TS-T---------T---TTVLFTRLAT---------------A-
-------GAT---H-----SRSSQEKSSQSQG----------------------------
PGIL---------VLLSL-LAVLLLLLV------GASLLV-WRMVRR--QVKV--AENAE
LSQN---------SSW-----GNEPS-----EPCYE------NLELQT-----HP-----
---PEG---TLKQRDME-VEYSLVA----------------------VP------RAEPY
YASVTFV--CQSQDSEATSMPP------KRPQE----E-P--EYSVIKK-----------
----------------------

------------------------------------------------------------
------------------------------------------------------------
-------------------DGVKEF-----------------------------------
---CF--SGCYL---L-----------GG

PF07686 // ENSGT00470000042273_0_Domain_0 (210, 319)

PK-ELRG------IVGESLRVQCRYEEEHRM
S-GKYWCRR---GY--WL----ACS-KIVET-RGSGE--EVTIGRMSIRDDPRDLTFFVT
MKHLVEDDSGSYACGINTT-------------RKDPKF-W--IMV--LVSKGPQILSVLT
HPES--------------------------------------------------------
---------I------PL-FIL--------------------------------------
---------A---S-------PLRSLHSKACF-CS----------T--Q-----SSQFRR
SFLG--NIHIQILVFLKV-P---IFLS-------LLCAVF-WVNRPWRT-LRK-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------VWVSSR-S--AVVL----------------------------------------
----L--WDF--------PGS---

PF07686 // ENSGT00470000042273_0_Domain_0 (205, 291)

SAVSGPR-AVRG------VEQGSLTVRCRYDPGYEP
F-VKWWCRG---AD--W----SSCR-FIVKTNHGSEK--EVKQGRVSIKDNWKDRPCDH-
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MRPLVL----------LWGCLVL-------------------------------
-------PGYE--------------ALT

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 337)

GPK-EISG------FEGDTVSLRCTYKKEMKV
H-RKYWCRQ---GGILL----SRCG-DTVYT-N-QDQ--EVTRGKMSIRDSLQDLWVTVT
MRDLTLKDSGKYWCGIDRLGR-------------DESF-E--VKL--IVFPGKRDSPV-P
TGTCCPSSPTPSFQPLTPTRR---LQPKAKAWLTQLPE--LTSPGLHPTVVTTKQGKTRV
KAPVFTEAAPAW-STGTSQVPSGISPHAGSSPHTATPARSAGTSQVPPGISPYAGR-SP-
-----H-TATS-PHA----GSS-----RP-VIWPP--LTTPKD---SRAV-T-SSVSKSS
VSIPMVRIMAPVLVLLSLLL----A--A------GLIAIGSHMLRRQRK--KSWLATET-
-QKN----------EKVYLE---TSLPGNGWTSEDS------MIDLAVP-----PE----
---CLRNPNPSAEKHNL-SQSLSSL------------------------------QSAEE
EAAPS-------LDAEEDVVVA----PPLHMSAE---ELAFSEFISV-------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
--KHLGLLELFL-M--HLGL---C------------------------------------
----F--PGS--------------YE

PF07686 // ENSGT00470000042273_0_Domain_0 (207, 320)

ITGPN-AVRG------LVGGSLTVECCYASTWKT
Y-SKWWCRG---SI--W----RRCN-ILVQT-TGSEQ--KVKKNKVSIRDNQKNFTFSVT
MEELTETDTDIYWCGIEKS

ENSGT00470000042273_0_Linker_0_1 (320, 542)

GT-------------DLGV-E--VKV--TIDPVCLAPTTVS
TTTTT------------TT-------------------------------T---------
---------------SK----------------ANMSTAPAETK-----------D-PP-
-------TVTS-SHS---------NDRNST--------D----GFNG--SDGVKDNAMTL
S

PF15330 // ENSGT00470000042273_0_Domain_1 (542, 733)

VLI--PTILAVLLLLLV-----AA-----------SLLT-LRIMKQQK--KA--AEMS-
-------------PEQ------VLQPQEG--DLCYA------NLTLQPTQ--ISRN-SSK
KKACAKPSLSVLDDQLE-VEYVTMAP---------------------LS------KEDIS
YAALSWEL-SNQEPTYCNMGHP-DTHVPSRSQQ----EHM--EYSTIKRP----------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MWLPWA-------LLLLW------------------------------------
----V--PGCFA---L-----------RG

PF07686 // ENSGT00470000042273_0_Domain_0 (210, 318)

PG-TMAG------PVGGSLSVQCWYEEKHKT
L-NKYWCRP---PRV-----LQ-CN-KIVET-KGPAG--K-MNSRVSIRDSPENLSFTVT
LENLTEEDAGTYWCGVD

ENSGT00470000042273_0_Linker_0_1 (318, 554)

TPWLQDL---------HDPIV-Q--VEV--SVFPAST-SMTPT
SITA--------------------------------------------------------
---------A-KTSTITT-V---------F---PPVSSTSLFA---------------V-
-------SAT---H-----STSNWEENEEVVS----------------------------
SQLP---------

PF15330 // ENSGT00470000042273_0_Domain_1 (554, 730)

LLLSL-LALLLPLLI------GASLLA-WRMFQK--RIKA--GKHSE
LSQN---------PKQ-----AAEQS-----ELHYA------NLELLS-----WP-----
---LQEE--PAPPREVQ-VEYSTVA----------------------AP------REELH
YASVVFD--S-----NTNRIAA------QSSGE----KKPDSHYSVIKKT----------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MWLCPA-------LLLLCL-----------------------------------
-------QGCSS---L-----------T

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 323)

GPG-SVSG------YVGGTVHVQCQYGKSYKD
H-VKYWCRG---KSD------TKCK-TIVEI-KGNGE--VKKSGRVSMRDHAGNFSMTVT
MENLSEDDAGSYWCKIQTFFIWDSW-------SRDPAV-L--VKV--HVLPATT-PM-AT
TLAV--------------------------------------------------------
--------------TT-----------ASL---PLVNTG---------------------
-------------------------------------HLRIST----SESFLLQLW----
PLLS--TIHFQILVLLKL-----PLFLS------MLCAVF-WVNRLQ-------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
----------------------------------------------------------MT
RRAG-AAGLPSA-------LLLLCV----PG-----------------------------
---------CLT---V-----------SG

PF07686 // ENSGT00470000042273_0_Domain_0 (210, 317)

PS-TVMG------TVGSSLSVQCQYEEKYKM
F-NKYWCRQ---PCL-----P-FWH-ETVET-TGSET--VVRSDRVIITDHPGDRTFTVT
LENLTAEDAGKYRCGIATILQEDGL----SGLLPEPFF-Q--VQV--LVSSASTTGS---
------------------------------------------------------------
---------RAENSVKTP-G---------S---P--------------------------
---------------------------------------------------TG-PGQCRG
S--S--NVYFLLLLLLKV-----PLLLS------TLGAIL-WLSRPWRT--PW--T----
-----------------------EPR-----AGELT------T--PYDH----WC-----
---P-----AWRHN-------------------------------------------PSD
Y-RKDF------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------C--------CTA--ERDIS

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 348)

GPR-TVSG------PEQGSLTVQCPYASLWKT
Y-NKWWCQG---AG--W----SSCR-ILVQT-SAEEQ--KVKRGRVSITDDQINFLIMVT
MEDLRMSDADVYWCGIERTGT-------------DLGV-K--VQV--TIDP---------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
----------------------------------------------------------MT
QRAG-AALLPSA-------LLLLCF----PG-----------------------------
---------CLT---V-----------SG

PF07686 // ENSGT00470000042273_0_Domain_0 (210, 318)

PS-TVMG------TVGESLSVQCQYEEKYKT
F-NKYWCRQ---PCL-----P-IWH-EMVET-RGSEG--MVRSDRVVITDHPGDLTFTVT
LENLTADDAGKYRCGIATILQEDGL----SGFLPDPFF-Q--VQV--LVSSAS-------
------------------------------------------------------------
---------STENSVKTP-G---------S---P--------------------------
---------------------------------------------------TR-PSQCEG
SLPS--CAYFLLLPLLKV-----PLLLS------ILGAIL-WVNRPWRT--PW--T----
-----------------------ESM-----NRRTC------H--TPCPL--EPC-----
---P-----ETQP-----------------------------------------------
-----F------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MPLLTL-F--SLFF---L------------------------------------
----L--SGY---------SI--ATEIT

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 321)

GPT-TVNG------LERGSLTVLCAYGSQWEA
Y-LKWWCRG---AV--W----GSCE-ILVKT-TGSEQ--EVKRGRLSIRDNQKNHTFTVT
MKDLRRDDADIYWCGIEKIG

ENSGT00470000042273_0_Linker_0_1 (321, 542)

T-------------DPGV-E--VQV--TIDPA--------
------------------------------------------------------------
------------------------------------LVTLEETS-----------S-SP-
-------TLSN-HHS---------DD---------------------------RHKLLKL
S

PF15330 // ENSGT00470000042273_0_Domain_1 (542, 732)

VLL--PLIFSILLLLLV-----AT-----------SLLV-WRMMKRQK--KA--AGMS-
-------------SEQ------VLQPLES--DLCYA------NLTRQQTQ--DFP-----
KKATTKPSSSAQADQLE-VEYVTMAP---------------------LL------REDIS
YASLTLAA-EDQEPTYCNTGRL-TSPISGGGPE----ESP--EYSTIRRH----------
----------------------

------------------------------------------------------------
MIP--R------------------------------------------------------
---GIGLWLPSA-------LL---------------------------------------
-LSRV--PGCFP---L-----------R

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 322)

GPS-SVTG------TVGESLSVTCQYEERFKM
N-KKYWCRGSH---V-----L-LCK-DIVKT-GGSE---EARNGRVSIRDDPDNLTFTVT
LESLTLEDAGTYMCGVDIPFTNHPL-------GIDEFF-K--VEL--SVVP------V--
----------------------------------------------------TGS-----
---------SLWSITTVP-E---------T---IR--SSLVHA---------------Q-
-------PS----------------------VT-------------TEDTIPA-PRARPW
SLLG--SLYLCILVFLEL-----PVFLC------MLCAVL-WVNRPQRC--CG-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
-----------------------------------------------MAASDTC--AGDT
PSRRRAVWLSPP-------LLLLLI-----------------------------------
Q-------GCFC---L----------

PF07686 // ENSGT00470000042273_0_Domain_0 (207, 319)

-SGPS-TVSG------TEGGSLSVQCRYEEEHRT
R-AKFWCRR---WCL-----P-GWE--IVMT-KPPEV--EARSGRVSIRDHPANLTFTVT
LEKLSMQDAGTYQCGVDEPWKWD--------I----FL-V---MV--LVSPAPATAL---
------------------------------------------------------------
------------TPAPSY-G---------G---PT---IPAMT---------------L-
-------P-----------------------AH-------------TGEKTPE-PSPHPR
SLLG--SVHGLLLVFLKL-----PLLLA------MLAAVL-WVNRPQRG--PG--R----
-----------------------GQV-----S----------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
-------MQLLL-I--PLLF---C------------------------------------
----L--SGS--------SVA--EEQISSLT

PF07686 // ENSGT00470000042273_0_Domain_0 (212, 317)

-TVSG------PEQGLLSVKCHYAPGWQL
Y-KKYWCQG---KA--W----SNCK-ILVIT-DGSER--EAKNGRVAIRDDQSSRVFTVT
VQQLRQDDAGIYWCGIERIWA-------------DPGF-R--IAV--TVGPASTTASTTA
-P-------R----TFTAT-------------------------------T---------
---------------AT----------------FTAPATQEKTE-----------G-SP-
-------TVSS-HHL-------------G------------------------ARPKMKL
STLL--PLLFAVLLLLLV-----VA-----------SLLA-WRMMKRQD--HA--AGTR-
-------------PEQ------TLQSLES--DLCYV------NLTLPQTG--SSPG-SSQ
RKAPRRS-ASAQAGQEE-VEYVTMAP---------------------VP------RGEIS
YASLSLGI-LDQEPTYSNASHF-ISHGAGRGHE----EST--EYSIIRKP----------
----------------------

------------------------------------------------------------
-----------------------------------------------------------M
TARAWASWRSSA-------LLLLLV-----------------------------------
-------PGYFP---L-----------SH

PF07686 // ENSGT00470000042273_0_Domain_0 (210, 318)

PM-TVAG------PVGGSLSVQCRYEKEHRT
L-NKFWCRP---PQI-----L-RCD-KIVET-KGSAG--K-RNGRVSIRDSPANLSFTVT
LENLTEEDAGTYWCGVDTPWLRD--------F-HDPIV-E--VEV--SVFPAGTT-----
----------------------------------------------------TAS-----
---------SPQSSMGTS-G---------P---PT--KLPVHT---------------W-
-------P-----------------------SV-------------TRKDSPE-PSPHPG
SLFS--NVRFLLLVLLEL-----PLLLS------MLGAVL-WVNRPQRS--SR--S----
-----------------------RQN-----WPKGE------NQ----------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
--MSPGRGLPWA-------LLLLW------------------------------------
----L--PGCFL---L-----------SG

PF07686 // ENSGT00470000042273_0_Domain_0 (210, 317)

SS-TMTG------TVGGSLRVQCQYEEEDKA
H-DKYWCRG---SLA-----VL-CD-KIVET-KDSVR--EVRSGRVTIRDHPANLSFTVT
LESLSLQDTGSYWCGV

ENSGT00470000042273_0_Linker_0_1 (317, 554)

DAPW---Q---------EDPAV-K--VMV--SVLPAPS-SKPPT
SVAV--------------------------------------------------------
---------A-RTSTTTT-K---------V---PAMSFTSHGG---------------G-
-------SST---H-----SSSSQENQQNVQD----------------------------
SRLL---------

PF15330 // ENSGT00470000042273_0_Domain_1 (554, 671)

VLLSL-LAVLLLLLV------GLSLLA-WQIWQR--WVKG--GEHSG
LSQN---------SSQ-----ASEQC-----EPQYA------NLQLLP-----WS-----
---LREE--PVTPRQVE-VEYSTVA----------------------IG------GEDLH
YTSVVFH--SQKQESNANGAPS------QGPQK----EEP--EYSVVKKPGNCLLGPSPL
VCSLHGDS--------------

------------------------------------------------------------
------------------------------------------------------------
------MYLLLL-F--PLLF---W------------------------------------
----V--SXX---------XX--

PF07686 // ENSGT00470000042273_0_Domain_0 (204, 348)

XXXITGPE-EVSG------MERGSLTVPCRYDPEWKT
--RKWWCRG---AA--W----SSCQ-ILVQT-TGSER--KVRKGRVSIMDSQGNFTFTVT
MEELRLDDADTYWCGIERTGV-------------DPGV-T--VKV--TIGPAPVT-----
------------------------------------------------------------
---------------------------------------PEGTT-----------G-SP-
-------TVSS-HYS------------VD------------------------SSDSMKL
SVLL--PLVFAVLLLFLV-----AA-----------SVLA-WKTAKRQK--KA--AGIS-
-------------PEQ------VLQPLES--DLCYA------NLTLQQTG--TAPS-SSR
KKTSTKLCPSAREDKAE-VEYITMAS---------------------LP------KEDIS
YAALSLDT-PDQELIYSNMDGL-ITHLHCGSHE----ETT--EYSTIMKP----------
----------------------

------------------------------------------------------------
-----------------------------------------------------------M
AQPHRAMWLPPA-------LLLLW------------------------------------
----V--PGCLS--

PF07686 // ENSGT00470000042273_0_Domain_0 (195, 333)

-L-----------SGPH-RVRG------IVGGSLSVECRYQEKFRN
N-NKYWCKN---SCL-----LS-PN--IVAT-TESKT--EVTQGHVSIRDHPANLTFTVT
LESLREEDAGTYRCGIDVSY------------KFDPTF-E--VEV--SVTPAPR-PTRPT
VT-V--------------------------------------------------------
---------K--TSTITT-K---------V---STVSFTTLAT---------------E-
-------GTT---H-----STSSQEEYDPTQTW---------------------------
-RLH---------ALLIS-LALLLLLLG------GISLLA-WRMVQR--WVKA--GEKPE
PPQS---------RSQ-----AAEQT-----ELCYA------NLELQT-----WP-----
---LSGK--PVQPTQAE-VEYSTVG----------------------PP------SGDLH
YSSIVFD--PRSQDSKADRIPS------EM---------P--VYSMVKKT----------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MWLPWV-------LLLLW------------------------------------
----V--PGCFA---L-----------RG

PF07686 // ENSGT00470000042273_0_Domain_0 (210, 318)

PG-TVYG------PVGGSLSVQCWYEEKHKT
L-NKYWCRS---PWV-----LR-CD-KIVET-KKPAG--K-VKGRVSIRDCPANLSFTVT
LESLTEEDAGTYWCGVD

ENSGT00470000042273_0_Linker_0_1 (318, 554)

TPWLQDL---------HDPYV-Q--VEV--SVLPAST-SMPPT
SITA--------------------------------------------------------
---------A-KTSTITT-V---------F---PSVSSTSMFA---------------V-
-------SAT---H-----STSNRKENEEVVS----------------------------
SQLP---------

PF15330 // ENSGT00470000042273_0_Domain_1 (554, 730)

LLLSL-LALLLLLLM------GASLLA-WRMFQK--RIKA--GEHSE
LSQK---------PKQ-----AAEQS-----ELHYA------NLELLS-----WP-----
---LQEE--PAPPREVQ-VEYSTVA----------------------AP------REELH
YASVVFD--S-----NTNRLAA------QRPQE----KEPDSYYSVIKKT----------
----------------------

------------------------------------------------------------
-----------------------------------------------------------M
IPRVMAVWLPSA-------LLLLQV-----------------------------------
-------PGCVP---L-----------R

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 349)

GPS-SMTG------TVGESLRVRCQYEEKHKA
N-SKTWCRGSL---L-----P-YCR-NIVKT-RASK---EARNGRVSIRDDPATLTFTVT
LDNLTLEDAGTYMCVITP------------SLGIDSYS-K--VVV--SVVPGKPLMSW--
----------------------------------------------------HSE-----
---------SQPNRTNTL-G---------S---LK--SSLVHT---------------Q-
-------PS----------------------VT-------------TEDTTPG-PSPHPR
SLLS--SIYFQLLVFLEV-----PLLLS------MLSAVL-WVNRPQRC--SG--E----
-----------------------KRH-----CPDYE------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MSLLTL-F--S-LF---W------------------------------------
----L--SGY---------SI--ATEIT

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 348)

GPT-TVNG------LERGSLTLRCAYGSQWET
Y-LKWWCRG---AV--W----SSCQ-ILVKT-TGSEQ--EVKRGRLSIRDDQKNHTFTVT
MKDLRRDDADTYWCGIERTGT-------------DLGV-K--VQV--

ENSGT00470000042273_0_Linker_0_1 (348, 542)

TIDPAST----AT
PT--------------MPT-------------------------------S---------
---------------TT----------------FTALVTLQETS-----------S-FP-
-------TLNS-HHL---------DN---------------------------RHKVLKL
S

PF15330 // ENSGT00470000042273_0_Domain_1 (542, 731)

VLL--PLVFSILLLLLV-----AA-----------SLLV-WRMMKRQK--KA--AGMS-
-------------SEQ------VLQSLES--DLCYA------NLTLQQTR--ASP-----
KKATTKPSSSAQADQVE-VEYVTMAP---------------------LL------REDIS
YASLTLAA-EDREPTYCNTDQL-TSPIPGRVPE----ESP--EYTTIRRH----------
----------------------

------------------------------------------------------------
-----------------------------------------------------------M
IPRVMDTWLPTA-------LLLLQA-----------------------------------
-------PGCVP---L-----------SG

PF07686 // ENSGT00470000042273_0_Domain_0 (210, 344)

PG-TVTG------IVGRSLSVQCQYEEKYKT
Y-NKYWCRKSL---L-------LCS-TIVKT-KSSG---EVRKDRVSIRDHPANLTFTVT
LEHLTLNDADTYECGLDTPWTEGF----------DKSV-E--VMV--FIVPEPNA-----
-----------------------------------------------------DS-----
---------SPGNNTSTQ-E---------P---ST--SPSVNT---------------Q-
-------PS----------------------DT-------------TED-TSE-PSPQPR
SLLS--SIYFRLLVFLEF-----PLLLS------MLSAIL-WVDRPQRY--PR--G----
-----------------------RQN-----QADYE------NQ----------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
-------------------YPLA-------GKGLPA-----LR--GQPQEGVR-------
EEASCGLDPGTC-----IQGIPTSVPALV-------------------------------
-------AGCG--------------ALVG

PF07686 // ENSGT00470000042273_0_Domain_0 (210, 318)

PK-EISG------FEGDTVSLQCTYREELRK
H-KKYWCKE---SGFII----SRCS-STVYA-GDNGQ--ERTEGRVSLQDNPQELTLKVT
LRKLTLQDAGKYFCGVSKLGR-------------DESF-L--VSL--LVFP---------
-GPCCPPSPTPSFQPL----ATRSLQPQAKAWQTPLPELR--------------------
------------------------------------------------------------
-------------------------TLRP-STQPE--PAWTED---TRLA-PS-RTSLSR
VSIPMVRILAPVLVLLSLLL----A--A------GLAALGSYLLRW-RK--EAQLATET-
-QRS----------EKVHLS---H------LSLDYA------VINLAGP-----PG----
---PRASPEPSVNPCTE-IRGLSQT------------------------------SEEEE
--VYFQD-------QEGDMIPG----PPLHMSGE---ELGFSKFISV-------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------

PF07686 // ENSGT00470000042273_0_Domain_0 (207, 345)

VTGPQ-SVRV------PLGGSLTVRCQYKQEWKS
N-VKWWCRG---EQ--W----SSCQ-FMAKS-SGF-----ETSGRTSIQDRRGNLTFIVT
IVNLEAGDTDTYWCGIEKALR-------------DHGH-R--VKV--TVSPPTTRMTVTT
KG--TPK-----------------------------------------------------
----------------------------------LTSS-AQESSN-------T-------
---------DS-GS-------SECCYIILVV-YSNDQQCSGGSSGGRNTG-FSGEIVKDL
RLLL--PLIFAILLILLV-----GI-----------SLVA-WRMVLSQK--KV--LQPPT
DQI------------S------LGFSSQF--SGMSL------KKTQPGK---------AE
WSGGRSINQSTQSSYDE-VEYAIMGS---------------------IQ------TKDIS
YASLTQLT-PGSNPTYDNVKPF-NSTHPRQDWQ----VET--EYSVIQ------------
----------------------

------------------------------------------------------------
-------------------MVHASL-----------------VTF---PLGF----KQ--
TAAGGASWDRVL-------GSDLCF-----------------------------------
-------PGCLS---L-----------T

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 320)

GPG-SVAG------TTGSSLRVRCQYEKAYKG
H-NKYWCRG---KYG------RVCR-KIVET-KGEEK--EKRNGRVSIRDHTDNLTFTVT
MENLNMNDAGSYWCRIQTIWILDVL-------SWDPSV-Q--VEV--SVFPAPSTTPGST
ACLA--------------------------------------------------------
--------------VP-----------DTL---QTVNDG---------------------
----------------------------------Q--NLST------KEMLT--HC--PG
SRLS--NIHFLLLVFLKL-----PLFLG------MVGAVL-WVNRPQRH--PG--GRERQ
LDPG---------SPP-----CSVLFP-G--MPCPG------I-QLFR------------
-----LD-----KRDLQ-ILCSRAG----------------------GQQLLDSGRTQVF
WGHWSRE-------------------------------GP-------------GS-----
----------------------

------------------------------------------------------------
------------------------------------------------------------
-----------MRL--LLLLLCCAA-----------------------------------
---LC--HPGWA---V-----------R

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 319)

GPG-TVEG------YIGGSLSVSCSYQEGYEM
K-PKFWCYP---GT--VRS-CSH---DIVIT-SEKEP--GVKQGRTSIWDNRTQRVFTVT
MKDLTARDHGTYRCGVRTDL------------LRWDVTDT--VRV--IVSSGPKSKPSAS
PSAW--------------------------------------------------------
---------T------VP---PDPI--SG------------PT---------------W-
-------TSP---Q---------QE-------TAK----------Q--TARPTSPEDLSE
EQLD--VVTGILIPCIAV-V---LFFL-------ALAAAV-LVILSWKR-KKALAGAPIE
MGST---------RGT------ANA---E--VLQYA------DISHAG-----E-E----
QSHLYSNIGAAPVSPQAATEYSEVKK---------------------PGQNLEG-NTETL
NTQVSRIPLEEQEQLYTNVVPR------RQRAA----Q----------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------T-EMKG------IMRK

PF07686 // ENSGT00470000042273_0_Domain_0 (227, 319)

SLRVQCQYKKEYRT
C-GKYWCKG---PS--RL----DCP-TIVET-KGSEE--EVKNGRVSIRDNRLNRRFTVT
VENLTAED-ASYACGIVKNF------------DLDLLL-W--FTV--SISQAQRGTVP--
-PSP--------------------------------------------------------
---------F------SQ-R----------------------------------------
-------------A-------LLQEIESAPTI-CQ----------S--FSFPS-RSGFQK
PEI---LLPL---VLTVL-S---LLLV-------GVSLLS-WRVVLRRK-KG--------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------T-EV

PF07686 // ENSGT00470000042273_0_Domain_0 (215, 319)

KG------IMGGSLSMQCPYEEKHRT
H-GKSWCKG---SS--LV----FCI-TLLET-NGSEG--EVKKGRVAIRDNHQNLIFSVT
MENLSADDAASYACGIDEPF------------SFEPLL-W--FTV--SISQETVVKTSKA
ATWT--------------------------------------------------------
---------A------E-------------------------------------------
-----------------------ITNTTQGLL-D--------------GNLPK-DKNSPR
SNV---FVVLIFLTSLKL-P---IFLS-------LVSMVI-WMKRLQRR-Q---------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MHLSLL-A--LFLF---W------------------------------------
----I--SGC--------FTA--QDPVT

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 336)

GPE-EVSG------YEQGSLTVWCRYGSWWKD
Y-SKYWCRG---PK--R----SSCE-IRVET-DASER--LVKENHVSIRDDQTNFTFTVT
MEDLRMSDAGIYWCGITKAGY-------------D

ENSGT00470000042273_0_Linker_0_1 (336, 542)

HMF-K--VHV--SINPV-------P
TT-------P----TTTST-------------------------------T---------
---------------TI----------------FTVTTTVKETS-----------T-LS-
-------TQTS-HYS---------DNRYDS----------------G--GVGDGNGFLDL
S

PF15330 // ENSGT00470000042273_0_Domain_1 (542, 732)

VLL--PVISAALLLLLL-----VV-----------SLIA-WRMVRRQK--KA--AGPP-
-------------SG---------QPLED--DLCYA------NLSLQQPR--TSP----L
KKGSSMS-SSGKDHQEE-VEYVTMAP---------------------FP------REEIS
YAALSLAS-LGQEPTYSNTACL-VTHGPRTNLGE---ETT--EYSSIRRPMP--------
----------------------

------------------------------------------------------------
-----------------------------------------------------------M
TPRGRAGWLPSA-------LLLLQL-----------------------------------
-------PGCLS--

PF07686 // ENSGT00470000042273_0_Domain_0 (195, 334)

-L-----------SGPR-SVTG------IVGGSLRVECRYQEAFVD
E-IKYWCKH---PCV-----S-PWK--IVET-RESER--EVRRGRVSIRDRPASLTFTVT
LESLREEDAGTYGCGIYVPL------------SRDPTF-Q--VEV--SVIPGSMTPT---
-----------------------------------------------------SS-----
---------K--RSTSTP-E---------S---PT--SLPVPT---------------W-
-------S-----------------------TM-------------SRQEAPD-PGQAHR
PLLG--SAHFLLLVFLKV-----PLLLG------MLGAVL-WVHRPLRS--SA--D----
-----------------------QQN-----VKQPG------PGELQPLL--CWK-----
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MRPLVL----------LWGCLVL-------------------------------
-------PGYE--------------ALK

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 336)

GPK-EISG------FEGDTVSLRCTYVEKMKE
H-RKYWCRQ---GGILV----SRCG-DIVYA-N-QDQ--EVTRGRMSIRDSPQELSMTVI
MRDLTLKDSGKYWCGIDRLGR-------------DESF-E--VTL--IVFPGKRDNAV-P
AGTCCPSSPTPSFQPLTPTRS---LQPKAKAWQTQLPE--PTSPGLHPTVVTAKQGKTGV
KAPVFTEAAPAW-STGTSQVPPGISPYAGSSPHTATPARSAGTSQVPPGISPYTGR-SP-
-----H-TATS-PHA----GSS-----RP-VVWLP--LTTPQD---SRAV-G-SSVSKPS
VSIPMVRMMAPVLVLLSLLL----A--A------GLIAFGSHMLRW-RK--KAWLATET-
-QKN----------EKVYLE---TSLPGNGWTTEDS------TIDLAVT-----PE----
---CLRNPNPSAVPSPE-TQNLSQS------------------------------TE-EE
EAARSLDD-D-----KEDVMEP----PPLQMSAE---ELAFSEFISV-------------
----------------------

------------------------------------------------------------
----------------------------------------------------------MR
SREGGAMWLSPA-L--LLLS----------------------------------------
----L--SGCF--------------SI

PF07686 // ENSGT00470000042273_0_Domain_0 (208, 349)

QGPE-SVRA------PEKGFVKVQCHYKQGWET
H-IKWWCRG---AH--W----VSCE-ILIQT-RGSEQ--EEKKDHVSIKDSHTDCTFTVT
MEGLRQNDSNTYWCGIQRLGP-------------DLGI-P--VQL--TVDPEGAASAPTS
S-----------------------------------------------------------
------------------------------------------------------------
--------S------------------------------------------VNSNIRVSI
SSQK--RNHYMLLVFVKV-----PILLI------LVGAIL-WLKGS-QR--VS--EEPG-
-----------------------NQPIYM--NFS-EL--LTKDMDA--------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MPLLTL-Y--LLLF---W------------------------------------
----L--SGY---------SI--ATEIT

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 349)

GPT-TVNG------LERGSLTVQCVYRSGWET
Y-LKWWCRG---AI--W----HDCK-ILVKT-TGSEQ--EVKRDRVSIKDNQKNRTFTVT
MEDLMKTDADTYWCGIEKTGN-------------DLGV-T--VQV--T

ENSGT00470000042273_0_Linker_0_1 (349, 542)

IDPAPT----PA
PT--------------TPT-------------------------------S---------
---------------AT----------------FTAPVTQEETS-----------S-SP-
-------TLTG-HHL---------DN---------------------------RHKLLKL
S

PF15330 // ENSGT00470000042273_0_Domain_1 (542, 732)

VLL--PLIFTILLLLSV-----AA-----------SLLA-WRMMKRQQ--KA--AGMS-
-------------PEQ------VLQPLEG--DLCYA------DLTLQLAG--ISP-----
QKATTKLS-SAQADQVE-VEYVTMAP---------------------LP------KEDIS
YASLTLGA-EDQEPTYCNMGHL-SSHLPGRGPE----EPK--EYSTISRP----------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MWLCAG-------LLLLCF-----------------------------------
-------QGCLS---L-----------SG

PF07686 // ENSGT00470000042273_0_Domain_0 (210, 343)

PG-SVSG------YVGGSLRVQCQYSPSYKG
Y-RKYWCRG---PHD------TTCK-TIVET-DGSEK--EKRSGQVSIRDHAANSTITVI
MENLSEDDAGSYWCKIQTSFIWDSW-------SRDPSV-S--VRV--HVFPATT-PM-ET
TLPA--------------------------------------------------------
--------------TT-----------AIL---PLVNSV---------------------
----------------------------------Q--NLRIST----NVMFLFQLW----
SLLS--SIQFQVLVFLKL-----PLFLS------MLCAIF-WVNRL--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
-------------L--LLLVLCCPT-----------------------------------
---PL--TGGWA---V----------

PF07686 // ENSGT00470000042273_0_Domain_0 (207, 336)

-RGPR-QVTV------GQGSSLTVSCSYKPRYKL
N-SKYWCRK---NF--PWF---CLT-YIIQT-DGSEG--TVTRDRVSIRDNHTANSFTVT
LSSVTPGDAGRYSCGVRKNV------------GTRRWH-N--TKV--MSIPASRMRRSRG
SAS---------------------------------------------------------
------------------------------------------------------------
------------------------------------------------PAAGTAP-----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
-----------------------------------------------------------M
TVRDWATWLPPA-------LLLLH------------------------------------
----I--LGCFS---L-----------RS

PF07686 // ENSGT00470000042273_0_Domain_0 (210, 348)

PN-TVMG------IVGGSLSVQCEYEEDYRA
A-KSVQCSY---IF------------NIVMT-EGSEK--EVRYGRLSIKNYSAHLTIEVT
LDNLTREDSSTYWCVFGRGH------------GLKYIT-E--VTV--LVSPAMIKASSPL
NSTG--------------------------------------------------------
---------I-------A-GLP----------------MTLTV---------------H-
--------TP---P-----RSTAQDSPGPSPQ----------------------PRCLLD
------SAPFLILVLLK-----LLLLFS------ALGGIL-WASRPQRSQGAG--QHRPD
D----------------------EDG----------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
----TCLLPALF-L--LVIP----------------------------------------
--------GE--------WGS---SA

PF07686 // ENSGT00470000042273_0_Domain_0 (207, 319)

ISGPR-AVRG------VEQGSLTVRCQYDPRYER
Y-VKWWCRG---AA--W----NNCR-FVVKT-TGSEK--EVKEGRVSIRDNQKDRSFTVT
MKELRLDDSDTYWCGIEIPGP-------------DLGN-P--VEV--TIDPGKSTCVC--
--------GR--------------------------------------------------
--------------------------------------------V-------SSGP-AL-
--------SRD-PTVP--------------------------------------QRECPR
PLLG--SVHFLLLVFLKV-----PLFLG------MLGAVL-WVNRPLRS--S--------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
-----------------------------------------------------------M
IPRGIRLWLPSA-------LLLSQI-----------------------------------
-------PGCVP---V-----------H

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 318)

GPS-TVTG------TVGESLSVSCQYEEKFKT
M-DKYWCRESL---K-----I-LCK-DSVMT-SGSE---EARNGRVTIRDHPDNLTFTVT
LEKLTLEDAGTYMCGVGRPFINGPFRIAD-DLWLTKTF-R--VEL--STVPGKPP--F--
----------------------------------------------------KGS-----
---------SPGNGINIP-E---------S---PT--SSLVHT---------------Q-
-------PN----------------------VT-------------TDNTIPA-PSPQPR
PLLS--SPHFWVLVSLEL-----PLFLT------MLGAVL-WVNRPQRC--YG--G----
-----------------------SSP-----RPCYE------NQ----------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
----------------------------------------------------------KW
DDLRKLLLLCVS-V--CVSS----------------------------------------
--------RS--------SGS---SA

PF07686 // ENSGT00470000042273_0_Domain_0 (207, 319)

ISGPR-AVRG------VERGSLTVRCRYDPGYEC
Y-VKWWCRG---AA--W----NNCH-FVIKT-TGSEK--EVKKGRVSIRDNQKDRLFTVT
MEELRLDDSDTYWCRIERTGP-------------DLGN-P--VEV--TIDPAPTVSIS--
--------TL--------------------------------------------------
--------------------------------------------A-------TSNA-NM-
--------FTA-PVAP----KENQGQ---------------LPAQESSEDLTSCPHVPHR
PLLG--SVHFLLLVFLKM-----PLLLG------MLGAVL-WVNRPLRS--SG-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
--MSPGRGLPWA-------LLLLWF-----------------------------------
-------PGCFL---L-----------SG

PF07686 // ENSGT00470000042273_0_Domain_0 (210, 318)

PS-KVTG------TVGGSLSVQCRYEEEHET
H-DKYWCRR---SHV-----L-LCD-KIVET-KGSMR--KATSGRVTIRDHPANRSFTVT
LESLTLEDEGTYSCGVDKPWLDS--------T---FKV-V--V----SVLPASATATAS-
------------------------------------------------------------
---------YLEGIRSTV-G---------P---PL--FLSMHT---------------W-
-------H-----------------------SS-------------TKQDTSR-PSPQPW
SLFS--SIHFLLLVFLKV-----PLFLS------MLSAVL-WVNRPQRG--SG--W----
-----------------------RD------TMMRL------PTLKTKI-----------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MWLPPA-L--LLLS----------------------------------------
----L--PGCF--------------SL

PF07686 // ENSGT00470000042273_0_Domain_0 (208, 345)

QGPE-SVRG------TEGGFVTVQCHYHPRWKT
Y-NKWWCRG---AR--R----HACK-ILVKT-RGSEQ--EEKSGRVSIKDNQRNLSFEVT
MEGLRQGDADTYWCGIERSFT-------------DPGT-P--VKV--TIDPAGTITTSSK
----PPD-----------------------------------------------------
--------------------------------------G-------------------P-
--------S------------------------------------------DESSIGVSS
GSYK--RTYYLLLVFVKV-----PILLV------LAGAVL-WLKGS-QR--VP--EEQW-
-----------------------GHPICK--NLNSEL--LTKDMTP--------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MRLLVL----------LWGCLVL-------------------------------
-------PGYE--------------ALK

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 318)

GPK-EISG------FEGDTVSLKCTYGEELRD
H-RKYWCRE---VGLFI----SRCA-GTIYS-GEEGQ--EITEGRVSIRDSRQELSFTVT
LQDLTLKDAGKYWCGVKKLGV-------------DEFI-P--ITL--TIFAG--------
--PCCPPSPS---------------------------------PTTTSLQPKAKQGKTVA
KTTPFPGTSRYG---------------------------HKRNS-------QCTGT-SP-
-----H-TATS-PPS----G-----SSRP-IMYLD--STSAED---ASPA-LSSGSSKPR
LSIPLVRILAPVLVLLSLLG----A--A------GLITFSSHLLRW-RK--EAQLATET-
-QRN----------EKVYLS---HLT----------------------------------
-------------------------------------------------------TEKEE
--ASSQA-------PEWDVVSP-----PLHTSEE----PGFSRFVSA-------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MWLPPA-------LLLLW------------------------------------
----V--SGCCS---L----------

PF07686 // ENSGT00470000042273_0_Domain_0 (207, 319)

-TGPD-TMTG------TVGGSLSVQCQYEEDYRD
A-QKYWCRK---KIVSL---LP-CD-KIVET-QIPDR--ERRINRVFIRDNPANLTFTVT
MEHLTVTDTGTYWCGINIPG---M---------FDPNF-K--VKV--SVSPASI-PVVPT
RITT--------------------------------------------------------
---------A-QTSTATS-E---------D---PTVPSTTLCA---------------V-
-------SAT---H-----SASIQEDSKQSPW----------------------------
SSLA---------LLLSF-LVILLLLLV------GTSLIL-WRKFQK--PVRA--GEHLE
LSQG---------PRQ-----AAEQS-----EEHYV------NLELLA-----WP-----
---LREE--PAPPKQVE-VEYSTVG----------------------AP------MEDPH
YSLVVFD--HQD--ATANGMSV------QRPRD----VEP--EYSVIRKP----------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MRLLVL----------LWGCLVL-------------------------------
-------PGYE--------------ALE

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 319)

GPK-EISG------FEGDTVSLRCTYREELRD
H-RKYWCRK---GGILF----SRCS-GTIYA-GKEGQ--ETTEGRVSIHDSRQELSLIVT
LWNLTLQDAGKYWCGVEKRGP-------------DESL-L--ISL--FVFPG--------
--PCCPPSPSPTFQLL----ATTRLQPKAKTQQTQPPG--LTSPGLYPAGTTAKQGKTGA
EATPFPGTSRYG---------------------------HERTS-------QYAAT-SP-
-----H-AATS-PPA----G-----SSRP-PKQLD--STSAED---ASPA-LSSSSSKPR
VSIPMVRVLAPVLVLLSLLS----A--A------GLIAFSSHLLLW-RK--EARQAMET-
-QRN----------EKVYLS---HLT----------------------------------
-------------------------------------------------------TEKEE
--APSQA-------PKEDVISM----PPLHTSEE---ELGFSKCVSV-------------
----------------------

------------------------------------------------------------
-----------------------------------------------------------M
GGRTTCLLLALF-L--LI------------------------------------------
---------I--------PGS---SAVS

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 316)

GPR-TVRG------VEQGSLTVRCRYDPGYEP
Y-VKWWCRG---AD--L----SSCR-FVVKTNLGSEK--EVKQGRVSIKDNWKDRSFTVT
MEKLRLDDSDTYRCGIERVGV-------------DLWD-D--VDV--TIDPAPTV-----
-----SISTR--------------------------------------------------
--------------------------------------------A-------TSNA-NM-
--------FTA-SVPP----EEN---------------------------------QGQL
PLLG--SVHFLLLVFLKV-----PLLLS------MLGAIV-WVNRPLRS--SR--GKPQE
NQ----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
--------------------------CRRCEPGCRSCS-----QGAGICAGCCVR----A
RREERTMQLLPA-L--LLFG----------------------------------------
----L--PGYC-------------

PF07686 // ENSGT00470000042273_0_Domain_0 (205, 350)

-FIQGPR-TVTG------GKQESTFVRCHYSSGLET
Y-NKWWCQG---RI--W----TFCR-VLVQT-SGTEQ--EV-RDHVSIRVNQKDHVVTVT
LKGLRREDAGTYWCGIEKPGV-------------DHGA-R--VKV--NVDPEEAATAISS
NSPARP------------------------------------------------------
------------------------------------------------------------
--------N------------------------------------------VTSNMGMSS
GSQR--LTHYVLLVFVKV-----PILLV------LVSVVL-WLRGT-RR--VP--EEQW-
-----------------------ILVAHG--NFHGPL--DVGP-----------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
----------------------------------------------------------RT
DSRGESLFPETW-------DSGLCF----PG-----------------------------
---------CLT---V-----------SG

PF07686 // ENSGT00470000042273_0_Domain_0 (210, 317)

PS-TVMG------TVGESLSVQCQYEEKYKM
F-NKYWCRQ---PCL-----P-IWH-EMVET-RGSEG--VVRSDRVVITDHPGDLTFTVT
LENLTADDAGKYRCGIATIVQEDGL----SGLLPDPFF-Q--VQV--LVSSAS-------
------------------------------------------------------------
---------STENSVKTP-G---------S---P--------------------------
---------------------------------------------------TR-PSQCQG
SLPS--CAYFLLLPLLKV-----PLLLS------ILGAIL-WVNRPWRT--PW--T----
-----------------------ESM-----NRRTC------H--TPHPL--EPC-----
---P-----EKQP-----------------------------------------------
-----L------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MWLSLA-L--LLLI----------------------------------------
----L--PGY--------SIA---AK

PF07686 // ENSGT00470000042273_0_Domain_0 (207, 319)

ITGPT-IVNG------SERGSLTVQCAYGSGWET
Y-LKWWCQG---AD--W----NYCN-ILVKT-NGSEQ--EVKKNRVSIRDNQKNHMFTVT
MENLKRDDADSYWCGIERPGI-------------DLGV-K--VQV--TINPDTQTAVPEW
TTTTASLAFT----AA--------------------------------------------
------------------------------------------------------------
-------------------------------------------------ATQKTSSPLTR
SPLS--STHFLFLFLLEL-----PLLLS------MLGTVL-WVNRPQRR--S--------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
-----------------------------------------------------------M
MPRVTKVWLPSA-------LLLLQV-----------------------------------
-------LGCVP---L-----------R

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 318)

GPR-KVAG------TVGESLSVQCQYEEKYRA
I-NKYWCRVSL---I-----R-YCQ-DVVKT-RASK---EARNGHVSIRDDPATLTFTVT
LENLIPEDAGTYMCGVDIPFINGSWVEV-------------------SVAPGK-------
-----------------------------------------------------HP-----
---------HVMNRTNTL-R---------L---PT--SSPVHT---------------Q-
-------SS----------------------VT-------------TEDTTPD-PTPPPR
SLLS--SIYFLILVFLEL-----PLLLS------MLSAVL-WVSRPQRC--SG--E----
-----------------------KRH-----CPDYE------NQ----------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
----------------------------------------------------------MT
QRAG-AAMLPSA-------LLLLCV----PG-----------------------------
---------CLT--

PF07686 // ENSGT00470000042273_0_Domain_0 (195, 318)

-V-----------SGPS-TVMG------AVGETLSVQCRYEEKYKT
F-NKYWCRQ---PCL-----P-IWQ-EMVET-RGSEG--AVRSDRVIITDHPGDLTFTVT
LENLTADDAGKYRCGIATILQEESL----FGFLPDPFF-Q--VQV--LVSSAS-------
------------------------------------------------------------
---------STENSVKTP-G---------S---P--------------------------
---------------------------------------------------TR-PSQCQG
SLPS--NTCFLLLPLLKV-----PLLLS------ILGAIL-WVNRPWRT--PW--T----
-----------------------ES-----------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MWLPPA-L--LLLS----------------------------------------
----L--SGCF--------------SI

PF07686 // ENSGT00470000042273_0_Domain_0 (208, 348)

QGPE-SVRA------PEQGSLTVQCHYKQGWET
Y-IKWWCRG---AR--W----DTCK-ILIET-RGSEQ--GEKSDRVSIKDNQKDRTFTVT
MEGLRRDDADVYWCGIERRGP-------------DLGT-R--VKV--IVDPEGAASTTAS
S-----------------------------------------------------------
------------------------------------------------------------
--------P------------------------------------------TNSNMAVFI
GSHK--RNHYMLLVFVKV-----PILLI------LVTAIL-WLKGS-QR--VP--EEPG-
-----------------------EQPIYM--NFS-KL--LTKDMAT--------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MWLPPA-L--LLLS----------------------------------------
----L--SGCF--------------SI

PF07686 // ENSGT00470000042273_0_Domain_0 (208, 337)

QGPE-SVKA------LEQGSLTVQCHYKQGWET
N-IKWWCRG---AR--W----DTCK-ILTRT-TGSEQ--GEKSDRVSIKDNQKDRMFTVT
MEGLRRDDADVYWCGIERTGP-------------DLGT-R--VKV--IIDPEGAASTTAS
S-----------------------------------------------------------
------------------------------------------------------------
--------P------------------------------------------TDSNMGVFI
GSHK--RNHYMLLVFVKV-----PILLI------LVTAIL-WLKGS-QR--VP--EEPG-
-----------------------EQPIYM--NFS-KL--LTKDMAT--------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MHLLLL-F--YLLR---R------------------------------------
----L--AGS-------------

PF07686 // ENSGT00470000042273_0_Domain_0 (204, 348)

-SAITGPG-AVSG------PEGGSLTVKCQYSPGWET
Y-EKWWCRG---AA--W----SSCK-FVVKT-TEPEK--EVKEGRVSIRDNRKSRTIAVT
MEKLRLNDADSYWCGIEKFGT-------------DLGV-R--VKV--TINPVSVNLE---
------------------------------------------------------------
-----------------------------------------ETS-----------D-SL-
-------AVTS-PDS------------NS------------------------GSVFLKA
NTLL--PFIFAVLLLLLM-----VT-----------SLVV-WRMMKQQK--KA--AEIS-
-------------PEQ------VLQPKEG--DMCYA------NLSLQQTE--N-SG-SSQ
KKASTRSSSPAQANAEE-VEYVTMTP---------------------FL------REGIA
CAALSLET-SDQEPTYSNMECF-ITRIPSRSHE----EPT--EYSAIRKP----------
----------------------

------------------------------------------------------------
-----------------------------------------------------------M
VWNGGVAWLPWA-------LLLLW------------------------------------
----V--PGCSS--

PF07686 // ENSGT00470000042273_0_Domain_0 (195, 317)

-L-----------RGPD-SVLG------TVGGSLSVRCQYKEGFRD
H-DKYWCKS---PC--------VWK-KIVET-TKSQR--EVTKGRVSIRDHPADLTFTVT
LKNLTEGDAGTYKCGI

ENSGT00470000042273_0_Linker_0_1 (317, 554)

DILWVD-------------PTF-S--VVV--SVNPATM-STSSA
SITV--------------------------------------------------------
---------TQ-ISTITA---EMKT--KLY---WSSSSPAPTT---------------T-
-------GAT---H-----SASSQEELQPSQ---S-------------------------
LGLQ---------

PF15330 // ENSGT00470000042273_0_Domain_1 (554, 731)

VLLSL-LALLLLLLG------GSSLLA-WRMIRRHRRVKA--GENSE
PLRT---------PGQ-----ATQQG-----ELCYA------NLELPM-----WP-----
---LRAE--PVQPRQVE-VEYSTVQK---------------------AS------REEPY
YSSVVFD--FQSEDSKANRIRS------QRTLE----QET--QYSMIKNT----------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MWLLSV-L--LLPV----------------------------------------
----V--QGSP-------------ALMAVSD-AV

PF07686 // ENSGT00470000042273_0_Domain_0 (215, 319)

SG------PMRGSLTVQCRYEPGWET
Y-NKWWCQG---AE--W----KSCH-ILVQT-DGSER--EARGDRVSIKDNQKLRVFTVT
MEELRWNNADTYWCGIERSGT-------------DLGV-E--VKV--TIDPVIVQCHYGP
GW----------------------------------------------------------
---------------ET----------------FVKSWCPDADLN-------SCAI-LV-
-------QTTG-SQL---------KKN-----------------------------Q--L
SIDQ--K---------KQ-----TF-----------SMAI-WGE----------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
MAADRAIWMETW-------DSGLCF-----------------------------------
-------PGCLS---L-----------T

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 316)

GPG-SVTG------TVGGSLRVWCQYESTYKG
Y-NKYWCQG---QYD------TSCE-SIVET-KGEEN--VEWNGRVSIRDHPEALAFTIT
MQNLNEDDAGSYWCKIQTVWILDSW-------SHDPLD-L--VRV--YVSPATKTPR-RT
TRPA--------------------------------------------------------
--------------TT-----------PIF---LVVNPG---------------------
----------------------------------R--NLSTR------EVL----TKNSG
FRLS--SPHFLLVVLLKL-----PLLLS------MLGAVF-WVNRPPRA--PA--GR---
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
--------LSPP-------LLLLLI-----------------------------------
QGLCL--PGCFC---L----------

PF07686 // ENSGT00470000042273_0_Domain_0 (207, 344)

-SGPS-TVSG------TEGGSLSVQCRYEEEHRM
Q-AKFWCRH---RCL-----P-GRE--IVMT-KPPEV--EARSGRVSIRDHPANLTFTVT
LENLSIQDAGTYQCGVDVPQGWD--------I----FF-L--VTV--LVSPGESPVIRPL
GE--------------------------------------------------GGP-----
---------GTCSGPRSG-G---------G---PT---IPAMT---------------L-
-------P-----------------------AH-------------TGEKPPE-PSPHPR
SLLG--SVHGLLLVFLKL-----PLLLA------MLAAVL-WVNRPQRG--PG--R----
-----------------------GQA-----APRGH------NP----------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------LMGPP

PF07686 // ENSGT00470000042273_0_Domain_0 (212, 320)

-EARG------PLGEDLTVQCWYGKGYEN
Y-IKYWCRG---TT--W----TSCH-IVVKT--GSEA--TVKSDRVSIRDIHTFCMFVVT
MRNLTVEDSGTYWCGIERPAM-------------DLMF-S--VKV--NVLPGNQTSLLQW
T-----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
MIP--RVI----------------------------------------------------
-----WLWLPSV-------LL---------------------------------------
-LSQV--PGCVP---L-----------H

PF07686 // ENSGT00470000042273_0_Domain_0 (209, 318)

GPS-SVTG------TVGESLSVTCQYEEGFKT
N-KKYWCRGSL---V-----L-LCE-DIVMT-GGSE---EDRNGRVSIRDDPDNLIFTVT
LESLTMEDAGTYMCAVDIPLIDHSF-------GIDKFF-K--VEL--FMVPGLRP--G--
----------------------------------------------------SS------
--------------TKIP-E---------P---TR--SSPADP---------------Q-
-------PS----------------------MT-------------TNDTIPA-PSPQPR
SLLS--SPYFCILVFLEL-----PLFLC------MLSAVL-WVNRPQRC--SG-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------VWLAPV-L--LLLF----------------------------------------
----L--PGE--------KTA---AKPGG

PF07686 // ENSGT00470000042273_0_Domain_0 (210, 321)

PK-VMRG------PERGSLTVRCRYGQGWKT
H-RKWWCRG---VD--W----ASCK-ILVIT-TGSEQ--EVKRDRVSIRDDQRNLTFTVT
MEELRRDDEDTYWCGIERTGT-------------DPGF-Q--VKV--TIDPGKSVSLSSW
AASTT-DVY---------------------------------------------------
------------------------------------------------------------
----------------------FCAA--------------------LEARSRS--FPVTM
SLLS--SVHFLLLLFLEV-----PLLLT------MLSAVL-WVNRPQRS--SW--GTQSQ
LGHE-----NQ-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MWLSSA-L--LLLS----------------------------------------
----F--PGCL--------------SI

PF07686 // ENSGT00470000042273_0_Domain_0 (208, 349)

QGPA-LVRG------PEKGSVTVLCRYSSRWQG
N-NKWWCRG---AN--W----NTCR-VLIRT-NGSEK--ERRSGRLSIRDNWRDNSLLVT
MEMLKQNDTDTYWCGIERFGT-------------DRGT-R--VKV--TVYSVGKDTTSSS
KLPSAL------------------------------------------------------
----------------------------------------------------------P-
-------TV------------------------------------------DSSAYMMSS
DLHK--RTHYILLVFVKV-----PVLLI------LAGVVL-WLKGSTQK--VP--EEHW-
-----------------------RDTLCS--SLDSEP--LAKDIDP--------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
-------RVPHVSS--TWNSHWPHW-----------------------------------
---EV--PGGSK--

PF07686 // ENSGT00470000042273_0_Domain_0 (195, 345)

-L-----------WGPQ-TVTS------TEGKSLKVSCQYNPDWER
N-RKLWCRG---AE--WR----SCK-IIIRT-SKSGG----NKGTVVIRDSPRYQTFTVT
MENVTEGDTDTYWCGIERA-------------ENDIGA-R--VRV--TIYKESLSLSVIP
GRSP--------------------------------------------------------
---------L------PR-PHQ-------------------PL---------------E-
-------SRD---LA----TASSSSPHSPHLPSTG----------W--TLISL-QTQPAR
SFLE--DVGILVLLFLKM-P---ILLG-------LAGAII-WMKRPQRA-RDGENGSRKC
--------------------------D-G--F----------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
-------------------------TSRRCKSGLKQSF----KP-AGILVCPQLRVRGAM
SRRDRTMWLSPA-L--LLLG----------------------------------------
----L--PG

PF07686 // ENSGT00470000042273_0_Domain_0 (190, 348)

CL--------------SIRGPE-SVRG------LERGSLTVRCRYDPGWEA
N-SKWWCRG---QF--W----SLCE-ILVQT-TQSAR--GE-LGRVSIRDNQKDRLITVT
MKELKRDDQDTYWCGISRVGT-------------DRGV-S--VKV--IIVPEGTTATAEN
CST---------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------NSH-TALF
GSHI--RTHYVLLVFVKV-----PILLI------LVGAVL-WLKEP-QS--DP--KEHL-
-----------------------EQPIYK--NLSSDL--TKDTIP---------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------

PF07686 // ENSGT00470000042273_0_Domain_0 (207, 348)

ISGPK-EVRG------GEWHSLSVQCHYDPGWET
Y-RKWWCRG---HD--W----ISCE-ILVIT-NGSEM---VKKNRVSIRDHPRSLMFTVI
MKELRREDTDTYWCGIERTGS-------------DPGV-P--VKV--IIEPGQAATTVPT
PT-------P----TITST-------------------------------A---------
---------------NA----------------F--TDTPEDSS-----------G-FL-
-------NVTS-LHP---------DDRAESVGDGGAGSQ----GRGH--GQVSSGDSLTL
CISL--PLFIVLLLLVLV-----VV-----------SLLV-WRVVKRQK--EA--AGIP-
-------------PEQ------VLQPPED--NVCYA------NLPWKQTG--ASLS-SFR
KRAPTEPSSSAQDDQGE-VEYITMAP---------------------FL------GTEVF
YEALSLDT-LDQDSIYSNTQDL-ITPLPSRSQE----ELI--QFSAIRKP----------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------MWLPPA-L--LLLG----------------------------------------
----L--SGCL--------------SI

PF07686 // ENSGT00470000042273_0_Domain_0 (208, 344)

QGPE-FVRG------PEQGLVTVQCRYNQGWET
Y-SKWWCRG---AK--W----NLCK-VLVQT-RGSQQ--EEKSGRVSIRDSWRDLSFTVT
MEGLRPDDTDTYWCGIRKVGT-------------DLGT-Q--VKV--IVESVGTASSSAS
SSSKPFA-----------------------------------------------------
--------------------------------------R-------------------P-
--------P------------------------------------------ANSNMGESS
DSSK--RTHYVLLAFVKV-----PILLI------LVGAIL-WLKGS-QR--VP--EE---
-------------------------PQET--DLHQLV--L--------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
-----------------------------------------------------------M
TARAWASWRPSA-------LLLLLV-----------------------------------
-------PGCFP--

PF07686 // ENSGT00470000042273_0_Domain_0 (195, 320)

-L-----------SGPS-TVAG------PVGGSLSVQCYYEEEHRT
R-NKFWCRP---PQI-----L-RCD-KIVET-EGPAG--K-RNGRVSIRDSPANLSFTVT
LENLTEEDAGTYWCGVDTPLLRD--------F-HDPVV-E--VEV--SVFPARTT-----
----------------------------------------------------TAS-----
---------SPQSSMDTS-G---------P---PT--QLPVHT---------------W-
-------H-----------------------SV-------------TRKDSPE-PSPHPG
SLFS--NVRFLLLVLLEL-----PLLLS------MLGAVL-WVNRPQRS--SR--S----
-----------------------RQS-----WPEGE------NQ----------------
------------------------------------------------------------
------------------------------------------------------------
----------------------