Query Results 

-------------------------MLQTTQLNCESPKMSACSDFVEHIWKPGSCKNCFC
LRSDHQLAAGHPQPRT-----GSLPA-PPR--LPPRS----VEDEGV--NGSPYCKPTIA
VKPTMMSSEASDVWTEASLS---AEVPQVIWRRAPSKLPLPK--QEDVPIVYLGSFRGVQ
KPASPSACTD-GSSHCPPAYAMVGLHSLQARGERNMAFHPVGFPDEKAGQEGKPTFPSQE
-LPSAQESFRQKLAAFAE-MTSGCHKGPRPCPSPQPPQ--ESLPSEDESDQRCSPSGDSE
GGEYCSI-LDCCPRTPAAKETIHAEGSQGRCGGGNSSP-MCWERGTSARSPEE-------
-------EKRSLSFPRD--------CCGQGPSA-NPAHLGPKKLSLNSEAA-SSDGLSCG
S-G--SSGTSSPFAPHLENDYCSLMKEA----------VLPGKQQDSDCHVVTSSRCP--
--EFQPPAHPREAAHLEPIYAESTKRKKAVSVPS-RPQAKAKQAPTA--------QGQVW
-TGDGRAQKTKSVWSRDKEGSDTAPQVLATITVMAAHPEEDHRTIYLSSPDSAVGVQWPQ
GPVGQDLE--A------GEEETVA----GQRPSSKESH-----PLDRSENTPKGRPAIPP
KLSKSSPGGSPASPSA-----SSLTDPSEG--TS-G-----------SRAPHSTS-----
------------------------------------------------------------
-------------RGSADPTSSCPTN-------DPARWPPPAA--ST--SALDQRRPRYQ
TGAWSRQCRIEEEEEVEQEM-SQ----SWGREMDNG---TVDHSNSSTWHRFHSTDIS--
SGQNSKIGSGMSKSASFAFEFPKDRSRLEAF-SPPPPPPK--SRHLLKMNKSSSDLEKVS
QGSAESLSPS-FRG-----VHISFTTSSTDSLASDSRTCSDGGQSSEP-----------T
HSPTLGG---KKLFAP-VPFPSGSTENMSPSGP-VQPPPLPQKKIVSRAAS-SPDGVFWT
QGSPKPRT---ASPKLTLSHSETNVSAHDESHFSCSVSPGNRHHPVFS-SEPLEKAFKD-
SGHWVPAPG--LVGSKSSCGSPSLQCKAAPS--TSSSQLSVSSQASSSST-QLQLHSLLS
SISSKEGTYAKLGGLYTQSLARLVAKCEDLFMGGQKKEL-HFNENNW-SLFKLTCNKPCC
D----SGDAIYYCATCSEDPSSTYAVKICKTPEPNT-ASYC-SPSVPVHFNIQQDCGHFV
ASVPSSMLTSP--NT-TKDPL-PVAPSQPPAQEQDCVVVITREVPYQTASDFVCDSAASH
QAEP

PF00069 // ENSGT00460000041554_1_Domain_1 (1385, 1623)

EVYERRVCFLLLQLCNGLEHLKEHGIIHRDLCLENLLLVHCSPQASPGPSHATPAL
S----------------------AATSPC-SPAVPSSTATPS-----LLTGTTCQGVPSE
KHLPRLIISNFLKAKQKPGG----TTNLQQKKSQARLAPEIVSASQYRKFDEFQTGILIY
ELLHQPNPFEVRAQLRERDYRREDLPPIPTLSLYSP---GLQQLAHLLLEADPIKRIRIG
EAKRVLQCLLWGPRRELVEPPGPSEEVLSSTLHNWIDMKRALMMMKFAEKAVDRRRGVEL
EDWLCCQYLAAAQPTALLQSLRLLQLL---------

-------------------------TREALGLSRKDLKMSACSDFVEHVWKPGSCKNCFS
PKSSHRLQTPPDVGAC-----GVLP-----NGVRTKAESPALEDEGV--NTPV-SKPTIA
VKPTMINSDVSDTWADVNMN---ADLSQVSWGMVSGKHLLLKSGDAQRLCRDNFGNGGVR
KPFLHGPPGE-CLSCCSPSYSMVGLRSLEGRVERNVSIHSLVLLGEVGKQESRAKDKLA-
-LLHQHQPLCPNPPALGDRGVGSSARNPS----SH-GREGAALPSEGDRA-RGSSSFEGE
GGEYCSI-TDCRREGSAP---RCAEGKGAWCEKESPAP-RGWRQRDAPEAARPSGRAVKF
SEEERRAASVAFCIAKE-----------QGDPSA--PSSERKKSSLC-------------
------AEAAAACALCQDKED--------------------------ADAAGGTSGPQQA
LVEPQC-------SRGDPIYAESTKRKKAQLKGL-SGAVSVEKPAHSPGTEQ--------
-ADGTW-RDGGWAWGTEKEYQDPATQVAAKITVMTAHTEDDHKTIFLSSPDSAVGVQWPC
VSSASHPDFGTSPPAVEPGEVFQAS----GSENGLRLH-----FAAPPKSSVTESPAIPP
KMSKNSQQGSEGSCVL--PASSPLARLGDGNNHDGA-------------GAHPLP-----
--------RSCVDTGG--------------------------------------------
--------------FGVSPSPCAHINGAS-----------VEESGRGLAGLSYDRRQKHY
TPTWAKQCRK-----------QALSTHPWAVGAEVGRADA----------------DPVD
ECPMVESQPGISKSS--SFEFPKEKSNGTEF-APPPPPPKKQSRRALKMNPNNAELERGS
NSSTESLSPP-FRS-----IHVSFTAGSTDSLSSDTQTGSDGRHSSEP-----------N
HSPPPAE---SQVFPS-GSFLPTSSEDALSAGP-SCPPPLPQKKMMSRTVS-SPDGFFGS
QTSSGRAA-GTASPRLNVSHSESNFCLREEPPFIHPAGLGGP-GTF--SSESLERASKG-
NSYWGSATSK-----STGACIPSR---NQQS--LSSSQLSVSSQVSSSSS--LHLHNLLS
NIDSKEGVYAKLGALYAESLRRLVAKCEDCFMREQKNEL-RFSENNW-SLFKLACNKPCC
D----SGDAIYYCATCSKDPSTTYAVKICKSQESKVAASYC-SPAVPVHFNIQQDCGHFV
ASVPSSMLLAS--DVEKSV-PGDGLRASRAASEHDCVVVITREVPSQTTADFVRDSVMLH
QAKPELYERRVCFLL

PF07714 // ENSGT00460000041554_1_Domain_2 (1396, 1422)

LQLCNGLEHLKEHGIIHRDLCLENLLLVPCKP-------------
--------------------------------------------------PMSCVKAKDD
KHLPRLIISNFLKAKQKPGS-----GDSKLKKSQARLAPEIVSASQYKKFDEFQTGILIY
ELLHQPNPFEEKVHLKEQEYSPEDLPALPSLSIYSR---GLQQLAHLLLEADPIKRVRIT
EAKRMLQCLLWGPRRELTEQPLSHEEALCQVLQNWVDMKRALLMMKFAERAVDTERSVEL
EDWLCCQYLASAEPASLSHTLKLLQLL---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------TTSGCHQGPGPLRESLTKRKKAAPVPS-KSQAKIEHAAAAQG------QGQVC
-TGNAWAQKTASGWGRDS--PDPTPQVSATITVMAAHPEEDHRTIYLSSPDSAVGVQWPR
GPVSQNSEVGE------EE--TSA----GQGLSSRQSH-----AHSASESKPKERPAIPP
KLSKSSPVGSPVSPSAGGPPVSPLADLSDGSSGG------------SSIGPQPPS-----
------------------------------------------------------------
-------------QGPADPAPSCRTNGVT--ISDPSRCPQPAA-----SSASEQRRPRFQ
AGTWSRQCRIEEEEEVEQELLSH----SWGRETKNG---PTDHSNSTTWHRLHPTDGS--
SGQNSKVGTGMSKSASFAFEFPKDRSGIETF-SPPPPPPK--SRHLLKMNKSSSDLEKVS
QGSAESLSPS-FRG-----VHVSFTTGSTDSLASDSRTCSDGGPSSEL-----------A
HSPTNSG---KKLFAP-VPFPSGSTEDVSPSGP-LQPPPLPQKKIVSRAAS-SPDGFFWT
QGSPKPRT---ASPKLNLSHSETN--VHDESHFSYSLSPGNRHHPVFSSSDPLEKAFKG-
SGHWLPAAG--LAGNRGGCGSPGLQCKGAPS--ASSSQLSVSSQASTGST-QLQLHGLLS
NISSKEGTYAKLGGLYTQSLARLVAKCEDLFMGGQKKEL-HFNENNW-SLFKLTCNKPCC
D----SGDAIYYCATCSEDPGSTYAVKICKTPEPKT-VSYC-SPSVPVHFNIQQDCGHFV
ASVPSSMLSSP--VA-PKDPV-PALPAQPPAQEQDCVVVITREVPHQTASDFVRDSAASH
QAEPE

PF00069 // ENSGT00460000041554_1_Domain_1 (1386, 1623)

AYERRVCFLLLQLCNGLEHLKEHGIIHRDLCLENLLLVHCXXXXXXXHQQL----
------------------------------------------------------------
-----------FEGQAEAGR----HPKPAAAEEPGPAGPEIVSASQYRKFDEFQTGILIY
ELLHQPNPFEVRAQLRERDYRREDLPPLPALSLYSP---GLQQLAHLLLEADPIKRIRIG
EAKRVLQCLLWGPRRELVQQPGTSEEALCGTLHNWIDMKRALMMMKFAEKAVDRRRGVEL
EDWLCCQYLASAEPGALLQSLKLLQLL---------

-------------------------MQRAIEVKRGGLKMSACSDFVEHIWKPGSCKNCFC
PRNFHQLPTSTPLTPLDLAGSGGL-I-QNLNGTRAKGESTPLEGDGI--ISLPYSKPTIA
VKPTMINSDVADVWADGNLN---ADNPQVTKRTAFRKHALMKPGEEQSACLEKYSQIISR
KPVIQNAPND-CNSHSPQVPSLISLSGLEGRADKSLTFRNMTFPSDAGTHEDGVQKPSNE
KLVLPYLGLCHKSSMFSDQCINSSLNS-EKYPHFHQ-RA-E-RSHLEKTSLSHSSDLESE
GGEYCSI-TNYCAEPPNHQSLDNTKNKVSWLGNENPTSTFQRQEAVV-------------
---NGRTESTGMGFNERGNRPLNSETDFQGEKR-YPHDYIYN--HLCSE-----TNVSAF
P-PDTILKSRSPFSSPQGNHSIALVREQ---------------EQAEGKHIENVSN----
--SVQQELSSQVDSQNEPIYAESTKRKKVQLNNS-NICARSDPSPYSP------------
------SHEKNPHLSCGREFQESTTQVAATITIMAAHGEDDNRTIFLSSPDSAVGVQWPC
VSPISNPESGKASPFFEPKELPQANREMASKENSLDLH-----SQITCKKVVGDTPAIPP
KLSKGSLPWG---EGSLLPPVSPTAEISDGKDHEDLD-TPRHGGNSPVFG----------
------------------------------------------------------------
---------------PSSSQS-SHV----------NRIF-PEEAGKGPVSSTAERRQKYY
NLAWSKQCRIEEEEEEEQGLLKI----AQKVEMENGAISP---SSPSDCHQ-----GEKC
S-LQENKPRGMSKSASFAFDFPKEKNGIE-F-SPPPPPPKKQSRHFLNMNQSKSEFERHS
SDSVENLTAP-CQG-----IHVTFQAGSTDSLNLETNAFTNGGQPCKM------------
---SRAG---KQVFPS-APFSSCSNKDRTPCKD-LQPPPLPQKKTVSRAVS-SPDGFYWG
PASPARAAIPPTSPKLNFSQSESNVCVREESSFGSNLGV---NHRTFSSSESFEKAFKGS
NFPFPCSGQN-----SNACC---SQNKNLPT--RSSSQHSMSTQVSSSGS-SLQLHNLLS
NIDNKEGVYAKLGGLYAESLRRLVSKCEDCFMRDQKSEL-HFSENNW-SLFKLICNKPCC
D----SGDAIYYCATCSKDPLSTYAVKICKSQDTKAATSCC-SPSVPVHFNIQQDCGHFV
ASVPSSMLKSAPVE---------SQGSSHVASE

PF00069 // ENSGT00460000041554_1_Domain_1 (1354, 1623)

QDCVVVITREVPQQTAADFVRESRAFH
QAKPELYERRVCFLLLQLCNGLEHLKEYSVIHRDLCLENLLLVHCGTR------------
--------------------------------------------------PGGCNKTKED
KHLPRLIISNFLKAKQKPAA----T-ESKGKKNQARLAPEIVSASQYKKFDEFQTGILIY
ELLHQPNPFEVKAHLRGQEYSPDDLPPLPNFSIYSR---GLQQLAHLLLEADPIKRIRIG
EAKRILQCLLWGPRKDLTDQLLNHEEALRGALYNWIDMKRALLMMKFAERAVDTERRIEL
EDWLCCQYLASADPLSLSKSLKLLQLL---------

-------------------------MHQTLQLNPESLKMSACSDFVEHIWKPGSCKNCFC
LRSDHPLAAGQPQPRA-----GNLP--PPR--LPPRPEHCRLEDEGV--NSSPYSKPTIA
VKPTMMSSEASEVWTEANLS---AEVSKVIW---PGKLPLPK--QEDVPIVYRGSFRSVQ
KPAGPSASAD-GNARCPPAYAMVGL---EARGEKSLAFHPVSFPDEKGGREDRPSVPYQD
-LPSAQESFRQKLAAFAG-TTSGCHKSP--YPSPQPLR--ESLPSEDDSDQRCSPSGDSE
GGEYCSI-LDCCPGSPSSKDVSQAE----RRGRGDCSPRRCWEQGPCARPTEE-------
-------KKHVLSLSRE--------CCNQGLPA-NPTRLGPKKSSLTLEAASSSDGLSCG
S-G--SSRASSPCAPHLESDYCSLVKEA-----------VPGKQQDPGCHEVTSSRCLGA
ASEPQPLAHPREATQPEPIYAESTKRKKAVPVSS-RPQPKAEQTSAAQSQAQ--A--QVR
TGHNTWSQKTASGWGQNS--PDLAPQVAATITVMAAHPEEDHRTIYLSSPDSAVGVQWPR
GPVSQDSQ---A-----GEGETSA----RQGLSSRESR-----RS---------------
---------------------------------GSG----------SGSGSQPAS-----
------------------------------------------------------------
-------------RGAVDAASFCRANS------DPARYPPPAAAS---SSALDQRRPRFQ
TGTWSRQCRIEEEEEVGQELLSQ----SWGRGTKNI---ITDHLHSTTWHRLNPADGS--
SGQNSKVGSGMSKSASFAFEFPKDRSGIEAF-SPPPPPPK--SRHLLKMNKSSSDLEKVS
QGSAESLSPS-FRG-----AHVSFTTGSTDSLASDSRTCSDGGPSYEP-----------A
HSPTISG---KKLFAP-VPFPSGSTEDVSPSGP-LQPPPLPQKKIVSRAAS-SPDGFFWT
QGSSKPRP---ASPKLSLSHSETN--VHDESHFSYSLNSGSRHHHVFS-SEPLEKAFKG-
NGHWVPAPG--LAGNKSGRGSPGPQCKGAPS--ASSSQLSVSSQASTCST-QLQLHSLLS
SISSKEGTYTKLGGLYTQSLARLVAKCEDLFMGGQKKEL-HFNENNW-SLFKLTCNKPCC
D----SGDAIYYCATCSEDPGSTYAVKICKTPEPKT-ASYG-CPSVPVHFNIQQDCGHFV
ASVPSSMLTSP--EA-PKDPA-CAPPAQPPAPEQDCVVVITREVPHQT

PF00069 // ENSGT00460000041554_1_Domain_1 (1369, 1623)

ASDFVRDSAASH
QAEPEAYERRVCFLLLQLCNGLEHLKEHGVIHRDLCLENLLLVHCAPQAAPAAAA-----
--------------------------------------------------SSAAAGAPAE
KQLPRLIISNFLKAKQKPGG----APNPQQQKSQARLAPEIVSASQYRKFDEFQTGILIY
ELLHQPNPFEVRARLRERDYRPEDLPPLPARSLYSP---GLQQLAHLLLEADPIKRVRIG
EAKRVLQCLLWGPRRELVEQPGTSEEALCATLHNWIDVKRALVMMKFAEKAVDRRRGVEL
EDWLCCQYLASAEPGALLQSLKLLQLL---------

--------------------------------------MSACSDFVEHIWKPGSCKNCFG
LRSDHQLAAGRPQPRA-----GSLPP-PPR--LPPRPENCRPEDEGV--NGSGYSKPTIA
VKPTMMSSEGSDVWTEASLS---TEVPQVIWRRTPGKLQLPK--KEDVPVVYLGSFRGVQ
KPSGPPACTD-GNPRCPPAYAMVGLHSLEARGERNTTFHPVSFPEEKE------------
-PPLAQDSFRQKLAAFTG-MTSGCHKGPRPCPSPQPLQG-ESLPSEDDSDQRCSPSGDSE
GGEYCSI-LDCCPGGPAISDA--VDGSRGRLGGGDCMP-ECWEQGTCAGPQQE-------
-------EKQVLNVPRE--------CCVQGPTA-TPPRLRPKNPSLTSEAA-SSDGLSCV
SGG--SSGASSPLAPHLESDYCSLVKEP-----------APGKQPDSGCHVATSSKCPGI
PEEPQPLAHPREALQPEPIYAESSKRKKAVPSAK-A-----EQAAAA--QAP--GQHQVW
-TGDARVQKTSSGWGQGRDSPDVAPHVATTITVIAAHPEEDHRTIYLSSPDSAVGVQWPR
GPVGQDLE---A-----SEEEPAT----GQGRGSKESH-----PHDVTENTPKGRPAIPP
KLSKSSPGGSPASPST-----SPLADLGEGS--SGG----------SNTGPQPLS-----
------------------------------------------------------------
-------------RIPADLTSSCQTDCVA--ANDSAKCPSPAT--SS--SALDQRRPKYQ
TGAWSHQCRIEEEEEVEQELLSQ----SWGRDVESCT---KN--------------HSNS
SGQSCKAGTGMSKSASFAFEFPKDRSRVEMF-SPPPPPPK--SRHLLKMNKSSSDLEKVS
QGSAESLSPS-FRG-----VHVSFTTGSSDSLASDSRTCSDGGPSYEP-----------T
HSPTING---KKLFAP-VPFPSGSTEDVSPSGS-VQPPPLPQKKIVSRAAS-SPDGFFWT
QGSPKPRT---ASPKLNLSHSETNVCVHDEAPFSYSLGSGNRHHHIFSSSEPLEKAFKG-
SGPWAPMLG--LAGNKGGCGSPSLQCRAATS--ASSSQLSVSSQASSGST-QLQLHSLLS
SISSKEGTYAKLGGLYTQSLARLVTKCEDLFMGGQKKEL-RFNENNW-SLFKLTCNKPCC
D----SGDAIYYCATCSEDPGSIYAVKICKTPEPKT-ASYC-SPSVPVHFNIQQDCGHFV
ASVPSSMLTSP--DTTSKDPL-PGPPSHPPAQEQDCVVVITREVPHQTASDFVRDSAASH
RAEPE

PF00069 // ENSGT00460000041554_1_Domain_1 (1386, 1623)

AYERRVCFLLLQLCNGLEHLKEHGVIHRDLCLENLLLAHCSPPAPPAPSSSATPA
PAP--------------------------------PTAPSAT-----PPAAPACQGGPGD
KHLPRLIISNFLKAKQKPGG----TSNLQQKKSQARLAPEIVSASQYRKFDEFQTGILIY
ELLHQPNPFEVRAQLREREYRREDLPPLPALSLYSP---GLQQLAHLLLEADPIKRIRIG
EAKRVLQCLLWGPRKELVEHPGTSEEALSSTLHNWIDMKRALMMMKFAEKAVDRRRGVEL
EDWLCCQYLASAEPGALLQSLKLLQLL---------

-------------------------MLQATQLNCESPKMSACSDFVEHIWKPGSCKNCFC
LRSDHQLAAGRPQPRT-----SSLPP-PPR--LPPKS----VEDESV--NGSPYCKPTIA
VKPTMMSSEASDVWTEASLS---TEVPQVIWRRAHGKLPLPK--QEDVPIVYLGSFRGVQ
KPASPSACKD-GSSHCPPAYAMVGLHSLQAQGERNMAFHPVGFPDEKAGQEGKPTFPCQE
-LPSAQESFRQKLAAFAG-MTSGCHKGPRPCPSPQPLQ--ESLPSEDESDQRCSPSGDSE
GGEYCSI-LDCCPRSSAAKDTAHSESSQGRCGRGSSSP-MCWEQGSCARPPEE-------
-------EKQSPSFPRE--------CCGQGPSA-HPPHLGPKKPSLNSEAASSSDGLSCG
S-G--SSGASSPFTPHLESDYCSLMKEA----------VPPGKQQDSACRVITSSRCT--
--ESQPPAHPREAAQPEPIYAESTKRKKAVPVPS-RPQAKAEQAAAA--------QGQVR
-TGDARAQKTPCVWSRDREGSDMAPQVSATITVMATHPEEDHRTIYLSSPDSAVGVQWPR
GPVGQDLE---A-----GKEEPVA----GQGPSSKESH-----PPDRSENTPQGRPAIPP
KLSKSSPSGSPASPSA-----SSLADPNEGSSG--------------SSKPQSSS-----
------------------------------------------------------------
-------------RDLADPTSSCRTS-------DLARGPPPAAS----TSASDQRWPRYQ
TSAWSRQCRIEEEEEVEQELLSQ----SWGREMDNG---TVDHSNSSTWHRLHPTDGS--
SGQNSKVGTGMSKSASFAFEFPKDRSRMEAF-SPPPPPPK--SRHLLKMNKSSSDLEKVS
QGSAESLSPS-FRG-----VHISFATSSTDSLASDSRTCSDGGPSSEP-----------A
HSPTISG---KKLFAP-VPFPLGSTENVSPSGS-VQPPPLPQKKIVSRAAS-SPDGVFWT
QGSPKPRT---ASPKLNLSHSETNVSAQDESHFGYSLSPGSR-HPIFSSSEPLEKAFKG-
SSPWVPAPG--LAGSKSSCGSPSLQCRAAPS--TSSSQLSVSSQASSSST-QLQLHSLLS
SISSKEGTYAKLGGLYTQSLARLVAKCEDLFMGGQKKEL-HFNENNW-SLFKLTCNKPCC
D----SGDAIYYCATCSEDPGSTYAVKICKTPEPKT-TSYS-SPSVPVHFNIQQDCGHFV
ASVPSSMLTSS--DT-TKDHL-PAAVSQPPAQEQDCVVVITREVPYQTASDFVRDSATSH
QA

PF00069 // ENSGT00460000041554_1_Domain_1 (1383, 1624)

EPEVYERRVCFLLLQLCNGLEHLKEHGIIHRDLCLENLLLVHCSPQACPGPSSAASTL
S----------------------TATSAC-SPAVPPSTVAPN-----PLAASTCQVVPSE
KHLPRLIISNFLKAKQKPGG----TANLQKKKSQARLAPEIVSASQYRKFDEFQTGILIY
ELLHQPNPFEVRAQLREQDYRREDLPPLPALSLYSP---GLQQLAHLLLEADPIKRIRIG
EAKHVLQCLLWGPRRELVEQPGSSEEVLCSTLHNWIDMKRALMMMKFAEKAVDRRRGVEL
EDWLCCQYLAAAEPAALLQSLKLLQLL---------

------------------------------------------------IWKPGSCKNCFC
LRSDHQLAPGHSLPRT-----GNLPP-PPR--LPPRPEVSRLEDEGV--NSSPYSKPTIA
VKPTMMNSETSDVWTEANMS---AEVSQVIWRRAPGKLPIPK--QEDVPIAYLGNVRGIQ
KPAGPPATTD-GQSRCPPAYTMISLHSLEARGERSTAFHPLIFHDEKAGREDKPTLSYPE
-LPSTQDSFRQKLATFAG-MTSVCHKGPG------PLR--ESLPSEDDCDQRCSPSGDSE
GGEYCSI-LDCCPGSPVAKDAAQTEGSQHRHGRVDCPP-ICWGQGRCSGPSEE-------
-------EKQTLNFPRE--------CCGQGSTE-NVPHLGPKKPSLTSEMASSSDGLSCG
S-G--SSGTSSPFAPHLESDYCSLMKEP----------TLGKQQDSSNCHGVTSSKCHGL
SGEPQTAAQPKETVQPEPIYAESTKRKKSIPAPS-RPQAKAEQPTPAQ------GQSQIR
-TANTWAQKTASGWGQGREGPDMISQVAATITVMAAHPEEDHRTIYLSSPDSAVGVQWPH
GPVSQDSE--A------GEE-TST----GQGHGSREDH-----RPDANENSPKRRPAIPP
KLSKSSPGGSPVSPST-----SPLSKLSEV-NSS-G-----------SIGPQLPS-----
------------------------------------------------------------
-------------RVPSDPASSCRANGVT--SNDSIRCPPPAT--SA--STLDQRRPRYQ
TGAWNRQCRIEEEEEVEQELLSQ----SWGSEMENG---TPDPSSSSTWHRIHPTDSS--
SEQNIKVGTGMSKSASFAFEFPKDRSGIETF-SPPPPPPK--SRHLLKMNKSSSDLEKVS
QGSAESLSPS-FRG-----IHVSFTTGSTDSLASDTRTCSDGGPSSEP-----------A
HSPTSSG---KKLFAP-VPFPSGSTEDVSPGNSQQQPPPLPQKKIVSRAAS-SPDGFFWT
QGSPKPRT---ASPKLNLSHSETNVCVHEESPFSYSSSPGSRHHHIFS-SEPLEKAFKG-
NGHWVPPAG--LLGSKNISRSSSLQNKGAPS--ASSSQLSVSSQASSSST-QLQLHSLLS
SISSKEGTYAKLGGLYAQSLVRLVAKCEDLFMGGQKKEL-HFNENNW-SLFK

PF00069 // ENSGT00460000041554_1_Domain_1 (1253, 1626)

LTCNKPCC
D----SGDAIYYCATCSEDPGNTYAVKICKTPEPKT-SSYC-SPSVPVHFNIQQDCGHFV
ASVPSSMLTSP--DT-LKDPP-PALPSQLPAQEQDCVVVITREVPHQTASDFVRDSVTSH
QCEPEVYERRVCFLLLQLCNGLEHLKEHGIIHRDLCLENLLLVHCIPQTTPGPSAATHCA
PVFPATSSA-----------------SPI-SSAPLPTSGTPC-----PPGTPACQGVPPE
KHLPRLIISNFLKAKQKPGS----TTNLQQKKSQARLAPEIVSASQYRKFDEFQTGILIY
ELLHQPNPFEVRAQLREQDYRQEDLPPLPTLSLYSP---GLQQLAHLLLEADPIKRICIG
EAKHVLQCLLWGPRRELVEQPGTSEEALCSTLHNWIDMKRALMMMKFAEKAVDRRRGVEL
EDWLCCQYLASAEPGALLQSLKLLQLL---------

-------------------------MHTAITLNSQGVKMSVCSEFVEHIWKPGSCKNCFH
PRSDHRQLQPLSDGKN-----GNLPALHSLNGIKLKPDISQDEDT---VIASLYTKPTIA
VKPTMLTSD-NEMWTEINST---ETLTQVSWKMSQTSNSLLKSGDISKSIL--DNF---N
KPFNQKFS---AFNDNTPSYVFNGLKSPDRKMG-INAVNNLTYVSHFSGQSDKATFIKEK
-LPITFEQTTN------GNLVNGDIKKL------SCIQE-ESTLLSLKSSSGCSS-----
-GTLSSTDRNTPPGTLLTRGTSVPQ-GTGKSGMGLC------------------------
--------------------------NLDNPTPIKPARKFQDKNCLKSLELGSSKNLNCS
SPKVTLHSESDALTNNLS--YT-FTKDNPLGSPPYKDSQISEFHLSKDCRKNLVKHSQRL
THPEEHLQFQAEGTNREPIYAESTKRKGVLGRLEIKPQSQRNS-----------------
-EKNVIHQDSPVG---EEKQEITTTQVAAKITVMAAHTEEDNRTIFLSSPDSAVGVQWTC
SSPLSSSENANMSPFVWGERIQGRQ-EIK----AVEVN----------------KRYL--
---------------------GPLSPKSQGNSITAVSS--------MLVKPEE-------
------------------------------------------------------------
-------------CASLKLSSPTHTAGILHLSSQKKESL--EV--NDRCLQSTERRHRYY
QAQWSRQCKIDEEEEEEVSVSQP----SRINVVSNGQLTK------SSFN---Y--EEKS
SVEEQRIRKGMSKSASCPVELSKANHEQDDASQPPPPPPKK--QTRLKMKKSSTELEVAS
LGSVESLGES-FKATNVSNVNVSFSTGSVDSL--DSRTCSETGHSYEA-----------V
NSPSVSPGGEKKHFTKILSLDSG--Q-DSQHG-AIQPPPLPMKKSMNRASS-VPDNSALG
RTNVSRTLLNLNNQRYNLSQSENNVCGEIATQSSLLLSPGEK-HVMFSSSESLEKCCRG-
SGHRNEVRS-----------RNSVQGKGPHA--FSSSQLSVSSH-STSGS-SLQLHHLLS
NIDSKEGMYGKLSGLYAQSMRRLVNKCENHFMRGQKQEH-HFNENNW-SLFKLTSNKPCC
I----AGDAIYYCVTCSRDPNNSYSVKMCKAEDTKS---QS-NLSLPVHFNIQQDCGNFV
ATVPSSMLHPPNIPKGPSSN--ESSQTVGPASEQECVVVITREVPYLTAAEFVEESGSTH
QLQPEVYERQVCLLL

PF07714 // ENSGT00460000041554_1_Domain_2 (1396, 1422)

LQLCNGLEHLKEHGIIHRDLCLENLLLVHWQNSP-----------
------------------------------------------------------EKIKDV
KYVPRLIVSNFSKAKQRSGC----E-ESKPRRDKTRLAPEIMAASQYKKFDEFQTGILIY
ELLHQPNPFEVRASLHEHDYSQKDLPSLPALSVYSR---GLQHLAHLLLEADPIKRIRIS
EAKRVLQCLLWGPRKDLTDQPFSHEEAFHCALQNWIDMKRALLMMKFAEQALEPQQNISL
EDWLCCQYLASADPCYLYKTLKLIKLI---------

-------------------------MHQTVRLNPESPKMSACSDFVEHIWKPGSCKNCFC
LRSDHQLAPGQPQPRA-----GHLPP-PPR--LPPRPDNCRLEDEGV--NGSPYSKPTIA
VKPTMMSSDASEVWTEANLS---ADVSQAGWLAGSQGGLLEQ------------GSRGLA
SRQP--APAE-NHPSSPSRGLGYGLNYVSGDAQKCSFLKKIFFQVFS-----CLDFSSFD
-LGSLETVISLEIKPF-------CSSRKSPS------Q----------------------
-GDQPTS-LSQSSTSPATL----AETRSNGTAKGGSIA-PSWTVALGAPLPRT-------
-------PHRLRVLSA------------DLAEG-SAHHCAGSRLSLTSEAASSSDGLSCG
S-A--SSGASSPFTPHLESDYCSLMKEP-----------MPGKQQDSGCHVVTSN-----
----------REAVQPEPIYAESTKRRKAVPAPS-KPQATVEQAAAARGQ----GQGQVR
-TANAWA------------------QVAATITVMAAHPEEDHRTIYLSSPDSAVGVQWPR
GPVSQDSE---A-----GDEEASA----GQGLSSRESH-----RLDASENTPKGKPAIPP
KLSKSSPGGSPVSPSP-----SPLSDLSEGSSTG--------------------------
------------------------------------------------------------
---------------------------------DSVPCHLPAATA----STLDQRRPRYQ
TGAWSRQCRIEEEDEVEQELLSQ----SWGREMENG---TPDPTNSSTWHRLRPMDSS--
SGQSGKVGTGMSKSASFAFEFPKDRSGIEVF-SPPPPPPK--SRFSRHLLKMNSDLEKVS
QGSAESLSPP-CRG-----VHVSFTTGSTDSLASDSRTCSDGGPSSEP-----------A
HSPTSSG---KKLFAP-VPFPSGSIEDVSPSGP-LQPPPLPQKKLVSRAAS-SPDGFFWT
QGSPKPRT---ASPKLNLSHSETNVCAHEEPRFSYSSSPGSRHHPIFSSSEPLEKTFKG-
NGHWVPIPG--LAGSKSGRG-------------ASSSQLSVSSQASTSST-QLQLHSLLS
SISSKEGTYAKLGGLYAQSLVRLVAKCEDLFMGGQKKEL-HFNENNW-SLFK

PF00069 // ENSGT00460000041554_1_Domain_1 (1253, 1626)

LTCNKPCC
D----SGDAIYYCATCSEDPGSTYAVKICKTPEPKT-ASYC-SPSVPVHFNIQQDCGHFV
ASVPSSMLTSP--DA-PKDSQ-PALPSHPPAQEQDCVVVITPEVPHQTASDFVRDSATSH
QSEPEAYERRVCFLLLQLCNGLEHLKEHGIIHRDLCLENLLLVHCAPQAS----------
-------------------------------------------------------EAPSE
KYLPRLIISNFLKAKQKPGG----TANLQQKKSQARLAPEIVSASQYRKFDEFQTGILIY
ELLHQPNPFEVRAQLREQDYRQEDLPPLPALSLYSP---GLQQLAHLLLEADPIKRIRIG
EAKRVLQCLLWGPRRELVEQPGTSEEVLCGTLHNWIDMKRALMMMKFAERAVDRRRGVEL
EDWLCCQW----------------------------

-------------------------MQRAICVNQEGLKMSVCSHFVEHVWKPGSCKNCFC
PKRSHRLQASL-EPEA-----SNLPS-RNLNGIRTKAEAAPPEDESG--VASPYSKPTIA
VKPTRINPDVSDAWADVNMN---ADISQVSWRMASENQPLAKPGEAQRTGLDHFSSSAVR
KPFLHATPND----CVPPCRQGCSRGGLESRGERAVPFRSLALEG---GWEDRAVLRNKE
KFAFPQRGLCQPPSALADSSPASTPDST-GWPRLGQGE--GTTLSSVSSDGRSSPGTESE
SGDYCSI-ARCSMESPAPSPQG----RVAWSDGGKPAP-RFWGWQDAAASPQAKARAVQR
CEEEGKRLDVDSGFQRE--------RCLRDSPQKN-ARPQRNPLALLPGAAALSDGVLS-
-----RSGSSSPLALPQENDYCALLEPS----------PLPRGSPVENA-----SDVPSP
A-PASRPAQHAQPAPGEPIYAESTKRKKVQPNSS-GAPSKREGPARSP------LREQAW
---SLW-REGPQGPSNGREYQDPATQVAAKITIMAAHTEEDNRTIFLSSPDSAVGVQWPC
ASPTSHPDFAMPSPSFGHREGSQAGREMGSGESSPWFH-----QPTQTQGIANESPTVPP
KLPTSSPSGSEGVQVPSV--SCPGTEIWGGN--------------------HPSD-----
------------------------------------------------------------
-------------ASTQFSSQNCPEPGPS--GAPPSLCSPAEEPSRGAPGPAYERRQKYS
GTAWSRQCRIEEEEEEGPGFLTG----MQAREAENGAACL------------QH--VEGC
SGQGK--KPGMSKSASFAFDFPKDRSETEEF-APPPPPPKKQPRHALKMNKSSSELEKVS
NGSAE--SPP-FRE-----SHVRFVAGSTDSLSSDTRTASEEGST---------------
-------------------------QDRSLDA-PEQPPPLPQKKTVSRALS-SPDGFFWG
PASPGRTA-NPSSPRLNLSHSESNVCVRRDSPFSCSSHVGGSHP--AASSESLEKACKG-
NGPWGPASNQ--SGR---ARLPNRAGQAFPS-----SPL-LASGPVPSVS-SLQLHTLLH
NIDSKEGVYAKLGGLYAESLRRLVAKCEDCFMRDQKTEL-RFHEKNW-SLFKLTCNKPCC
V----SGDAVYYCATCAKDPASTYAVKICKTPESKVSASYH-SPSVPVHFNIQQDCGHFV
ASVPSSMLLSA--DVANSTPPSDGPGLSRSSSEQDC

PF00069 // ENSGT00460000041554_1_Domain_1 (1357, 1623)

VVVITREVPQQTAADFVRETAAYH
QSKPELYERRVTFLLLQLCHGLEHLKDHSIIHRDLCLENLLLVHCKPLAGGG--------
-------------------------------------------------------KAKEE
KHLPRLIVSNFLKAKQKPGT----G-DSKLKKNQARLAPEIVSASQYKKFDEFQTGILIY
ELLHRPNPFEVRPHLREQDYSRDDLPPLPSLSIYSR---GLQQLAHLLLEADPIKRVCIT
EAKRMLQCLLWGPRKDLTDQPRNHEEVLCSALQNWIDMKRALLMMKFAERAVDTERSVEL
EDWLCCQYLASADPASLLNTLKLLQLL---------

-------------------------MHQTLRLNPESPKMSACSDFVEHIWKPGSCKNCFC
LRSDHQLVAGPPQPRV-----GSLPP-PPR--QPPRPENGRLEDEGV--NSSPYSKPTIA
VKPTMMSSEASDVWTEASLS---AEVSQVIWRRAPGKLPLPK--QEDAHVVYLGSFRSVQ
KPAGPSASPDGNA-RCPPAYTMVGLHNLEPHGEKNIAFHPVSFPDEKAGHKEKPSFSYQD
-RPSAQESFRQKLAAFSG-TTSSCHQSPA------PLR--ESLPSEDDSDQRCSPSGDSE
GGEYCSI-LDCCPGSPVAKAASQAAGSRGRHSDRDCSP-TCWEREKCAGSSEQ-------
-------EKQGPSFPRE--------CCSQGTTA-HSSRLGPKKPSLTSEAATSSDGLSCG
SG----SGASSPFIPHLESEYCSLIKEP-----------APGKQQDPGCPGVVSSRCLGP
MGESPPPAHPREATQPEPIYAESTKRKKPTPVPS-KPQAKTEHAAAAQG----QGQGQVW
-MGNVWAQKTASGWGQDS--PDPAPQVAATITVMAAHPEEDHRTIYLSSPDSAVGVQWPR
GPVSQDSEVGE------EETETSA----GQGLNSRESH-----AHSASESKPKGRPAIPP
KLSKSSPGGSPVSPS-----ASPLADLSDGSSSG------------SGIGPQPPS-----
------------------------------------------------------------
-------------RGPAEPAPPCRTNSVT--ISDPSRCPHPAA-----SSALDQRRPRFQ
AGTWSRQCRIEEEEEVEQELLSH----SWGRETKNG---PTDRSNTTTWHRLCPTNGS--
SGQNSKVGTGMSKSASFAFEFPKDRSGIETF-SPPPPPPK--SRHLLKMNKSSSDLEKVS
QGSAESLSPS-FRG-----VHISFTTGSTDSLASDSRTCNDGGPSSEL-----------A
HSPTNSG---KKLFAP-VPFPSGSTEDVSSSGP-LQPPPLPQKKIVSRAAS-SPDGFFWT
QGSPKPRT---ASPKLNLSHSETN--VHDESHFSRSLSSGNRHHPAFSSSEPLEKAFKG-
SGHWVSAAG--LSGSRSGCRSPGLQCKGDPS--ASSSQLSVSSQASTGST-QLQLHGLLS
SISSKEGTYAKLGGLYTQSLARLVAKCEDLFMGGQKKEL-HFNENNW-SLFKLTCNKPCC
D----SGDAIYYCATCSEDAGSTYAVKICKTPEPKT-VSYC-SPSVPVHFNIQQDCGHFV
ASVPSSMLTSH--DP-PKDPV-PALPAHPPAQEQDCVVVITREVPHQTASDFVRDSAATH
QAEPE

PF00069 // ENSGT00460000041554_1_Domain_1 (1386, 1623)

AYERRVCFLLLQLCNGLEHLKEHGIIHRDLCLENLLLVHCTPPAAPAPAA-----
-------------------AAP-----PC-SSGALPAGGAPSPA-----AGPACQGGPGE
KQLPRLIISNFLKAKQKPGG----TPNLQQKKSQARLAPEIVSASQYRKFDEFQTGILIY
ELLHQPNPFEVRAQLRERDYRQEDLPPLPALSLYSP---GLQQLAHLLLEADPIKRIRIG
EAKRVLQCLLWGPRRELVQQPGTSEEALCGTLHNWIDMKRALMMMKFAEKAVDRRRGVEL
EDWLCCQYLASAEPGALLQSLKLLQLL---------

------------------------------------------------------------
------------------------------------------------------------
----------------------------VIWRRAPGKLPLPK--EEDVPVVYLGSFRGIQ
KPVGPSAPAD-GHPRCPPACAMVSLQSPEPRGEQNAALHPVSFLDDKLGREAKTTIPYQE
-LTSAQESFRQKLATFAG-MTSGCHKGPG------PLR--ESLPSEDDSDQRCSPSGDSE
GGEYCSI-LDCCPGSPGTGNASQANGSRHGHGGGDCAP-VCWEPTMFSRA-SK-------
-------GKRALSFPKE--------CCIQGPTE-NPPRLGPKKQSLTSDAACSSDGLSCS
AN----SREGCPSAPHFESNYCSLLREP----------XXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---X-XXX-XXXXXX--------XXXXX
-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXX-----XXXXXXX----GQGLSSREGH-----HQAASENMPKGRPAIPP
KLSKSSPGGSPVSSSA-----SPLSDLSEGNSG-------------GGTGLQPPS-----
------------------------------------------------------------
-------------RSLADSASSCRAKGVP--TSDSVKGPPPATTT----SALDQRRPWYQ
TGAWSRQCRIEEEEEVEQDLLSQ----SWGREVENG---PTDPSNSSTWHRLRPTDSS--
SGQNSKIGTGMSKSASFAFEFPKDRSGIEAF-SPPPPPPK--SRHLLKMNKSSSDLEKVS
QGSAESLSPS-FRG-----VHVGFTTGSTDSLASDSRTCSDGGPSSEP-----------T
HSPTS-G---KKLFAP-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXX
XXXXXXXX------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-
XXXXXXXXX--XXXXX-----XXXXXXXXXX--XXXXXXXXXXXXXXXXX-XXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXICKTPEPKT-ASYC-SPSVPVHFNIQQDCGHFV
ASVPSSMLTSP--DA-PKDPL-SALPSHPPAQEQDCVVVITREVPHQTALDFVRGSATSH
QSEPEVYERRVCFLL

PF07714 // ENSGT00460000041554_1_Domain_2 (1396, 1422)

LQLCNGLEHLKEHGIIHRDLCLENLLLVHCTPQASPAHPTPPV--
--S-----------------SAASSAPPC-PSATPSSGPSPT-----PPAAPACQGGPSE
KHLPRLIISNFLKAKQKPGG----TTNLQQKKSQARLAPEIVSASQYRKFDEFQTGILIY
ELLHQPNPFEVRAQLREQDYRQENL-PLPALSLYSP---GLQQLAHLLLEADPIKRFRIE
P--KRVQYLLWGPRRELVEQPGTSEEVLCTTLNNWIDMKRALMMM-FAEKAVDRRRGVEL
EDWLCCQYLASAEPGALLQSLKLLQLL---------

--------------------------------------MSACSDFVEHIWKPGSCKNCFC
LRSDHQLTAGHPKARA-----SSLPA-GAR--LPARPEICRLEDEGV--NGLAYSKPTIA
VKPTMMTSETADLWTEASLS---AEVPKVNWRRTPGKLLLQK--QEDGPIVYLGSFRGMQ
KAAGPLACTD-SNSRCPPAYTMVGLHNLEARVDRNTALQPVNFQEEKAGREE--------
-LPSAQESFRQKLAAFTG-MTSSCLKGPRPCTSPQPLR--ESLPSEDDSDQRCSPSGDSE
GGEYCSI-LDCRPESRDAVHNTEG--S--GRRRGDCSP-ICWEQGTCTRPTEE-------
-------EKQALNFPRE--------CCGQGSTA-NPPHLGPKKPSLNSEAASSSDGLSCG
S-S--RSGANSPFAPHLENDYCSLVKEP-----------TSVKQQDSGCHLVNSGKYVGQ
AVDLQPPALPREAVQPEPIYAESAKRKKAAPVPQ-RPEPKKEQV----------SSGQVW
-TGDTWSQKTPSGWSQEREGPNAAPQVATTITVIAAHPEEDHRTIYLSSPDSAVGVQWPR
GSLNQDLH---G-----SGEEPLV----VQGLSSRESH-----PHNMTENSSKEKPAIPP
KLSKSSPGGSPVSPAA-----PPLTDHSDGNTSG------------SSVGSQPSS-----
------------------------------------------------------------
-------------RVPTNLTSSCQTNGVAA--GDPAKCPPQA-NS----SVLDQRRPRYQ
TGAWSRQCRIEEEEEVGQELLSQ----SWGRELENG---IADHSNSSTWHRLHPI-D-GA
SGQNGKTNSGMSKSASFAFEFPKDRGRLESF-SPPPPPPK--SRHLLKMNKSSSDLEKVS
QSSAESLSPS-FRG-----AHVSFTTGSTDSLASDSRTCSDGGPSCEA-----------T
HSPTISG---KKLFAP-VPFPSGSTEDVSPS-GPAQPPPLPQKKIVSRAAS-SPDGFFWT
QGSPKPRT---ASPKLNLSHSETNVCAHDEPPLSYSLNSGNHPHHVFSSSEPLEKAFKG-
SVPWAPALG--PANSKGGCGSPNLQGRAATS--TSSSQLSVSSQASTGSS-QLQLHSLLS
SISSKEGTYAKLGGLYTQSLARLVTKCEDLFMGGLKTEL-RFDENSW-SLFKLICNKPCC
D----SGDAIYYGATCSKDPDSIYAVKICKTPEPKS-ASYC-SPSVPVHFNIQQDCGHFV
ASVPSSMLAF--PDTSSKDPA-PAAPSHTPAQEQDCVVVITREVPHQTASDFVRDSVASH
RA

PF00069 // ENSGT00460000041554_1_Domain_1 (1383, 1623)

EPEVYERRVCFLLLQLCNGLEHLKEHGIIHRDLCLENLLLVHCNPQSSPGPSANPSVP
T------------------------------------TTSRCP-SAAPAATTACQGGPGE
KHLPRLIISNFLKAKQKPGG----TTNLQQKKSQARLAPEIVSASQYRKFDEFQTGILIY
ELLHQPNPFEVRAQLRERDYRREDLPPLPTLSLYSP---GLQQLAHLLLEADPIKRIRIG
EAKRVLQCLLWGPRRELVEQPCPSEEVLCNTLHNWIDMKRALMMMKFAEKAVERRRGVEL
EDWLCCQYLASAEPGALLQSLKLLQLL---------

--------------------------------------MSACSDFVEHIWKPGSCKNCFC
LRSDHQLATGLPKARA-----SSLPA-VSR--LPARPENCRLEDEGV--NGLAYSKPTIA
VKPTMMSSETSDLWTEASLS---AEVPKVNWRRSPGKLPLQK--QEDGPIVYLGSFRGMQ
KPAGSLACTD-GNSCCPPAYAMVGLHSLEARVEKNTAFQPVNFQEEKAGREE--------
-LPSAQESFRQKLAAFAG-LTSSCPKGPRPCPSPQPLR--ESLPSEDDSDQRCSPSGDSE
GGEYCSI-LDCCPEAKNAVLSTES--P--GRRGGACSP-VCWEQRTCTKGTEE-------
-------EKRVLNSPRE--------CCGQGSTA-NPPRLGPKKPSLNSEAASSSDGLSCG
S-R--SSGASSPFAPHPENDYCSLVKEP-----------GPGKQQDSGCHVITAGKCVGQ
AGELQPPALPREAVQPEPIYAESTKRKKAVPVPS-RSETKAEQVAADH------SQGQVW
-TGDTWAQKPSSGWSQDKEGTSMAPQVATTITVIAAHSEEDHRTIYLSSPDSAVGVQWPH
GSLTQDIQ---A-----GEEEPSV----VQGLSSRESH-----PHNVTENLPKEKPAIPP
KLSKSSPGGSPASPAA-----SPLTDHSEGNTGC------------ISVGPQLLS-----
------------------------------------------------------------
-------------RVPTNRTSSCQTNGVA--TGDLAKCPPPATSS----SALDQRRPRYQ
TGAWSRQCRIEEEKEVGQELLSQ----SWGKEVGNG---TTDHSNSSTWHRLHPTDG-SS
-GHYNKASTGMSKSASFAFEFPKDRSRMEAF-SPPPPPPK--SRHLLKMNKSSSDLEKVS
QGSAESLSPS-FRG-----AHVSFTTGSTDSLASDSRTCSDGGPSYEP-----------A
HSPTISG---KKLFAP-VPFPSGSTEDVSPS-GPAQPPPLPQKKIVSRAAS-SPDGFFWT
QGSPKPRT---TSPKLNLSHSDTNVCVHDEPPFSYSLNSGDHPHPVFSSSEPLEKAFKG-
SAPWGPALG--LASSKGSCGSPSLPCRAATS--TSSSQLSVSSQASSGST-QLQLHSLLS
SISSKEGTYAKLGGLYTQSLARLVTKCEDLFMGGQKKEL-RFNENNW-SLFKLTCNKPCC
D----SGDAIYYCATCSEDPGSTYAVKICKTPEPKS-ASYC-SPSVPVHFNIQQDCGHFV
ASVPSSMLASP--DTSSKDPAVPAAPSHSPAQEQDCVVVITREVPHQTASDFVRDSTASH
RA

PF00069 // ENSGT00460000041554_1_Domain_1 (1383, 1623)

EPEVYERRVCFLLLQLCNGLEHLKEHGIIHRDLCLENLLLAHCSPQGSPGPSGTPTAP
TTT---T-----------------------------TTTSRCS-SATPTATTACQGGPGE
KHLPRLIISNFLKAKQKPGS----TTNLQQKKSQARLAPEIVSASQYRKFDEFQTGILIY
ELLHQPNPFEVRAQLRERDYRREDLPPLPTLSLYSP---GLQQLAHLLLEADPIKRIRIG
EAKRVLQCLLWGPRRELVEQPCTSEEVLCSTLHNWIDMKRALMMMKFAEKAVDRRRGVEL
EDWLCCQYLASAEPGALLQSLKLLQLL---------

-------------------------MLQTTQLNCESPKMSACSDFVEHIWKPGSCKNCFC
LRSDHQLAAGGPQPRT-----GSLPP-PPR--LPPKS----VEDEGV--NGSPYCKPTIA
VKPTMMSSETSDVWTEASLS---AEVPQVIWSRAHGKLPLPK--QEDVPIVYLGSFRGVQ
KPAGPSACTD-GSSHCPPAYAMVGLHSLQARGERNMAFHPVGFPDEKAGQEGKPTFPCQE
-LPSAQESFRQKLAAFAE-MTSSCHKSPRPCPSPQPVQ--ESLPSEDESDQRCSPSGDSE
GGEYCSI-LDCCPRSLAAKDPTHVESLQGRCGGGNSSP-MCWEQGTCAGPPEE-------
-------EKQSPSFPRE--------CCGQGLSA-NPPHLGPQKPSLNSEAASSSDGLSYG
S-S--SSGASSPFTPHLESDYCSLVKEA----------VLPGKQQDSVCHAVTSSRCS--
--ESQPPAQPREAAQPEPIYAESSKRKKAVPVPS-RPQAKAEQATAA--------QGQVW
-TSDARAQKTPSVWSRDREGSDMAPQVSTTITVMAAHPEEDHRTIYLSSPDSAVGVQWPR
GPVGQDLE--A------GKEETVS----GHGPSSKESH-----PHGRAENMPKGRPAIPP
KLSKSSPGS-PASRSA-----SPPANPAEG--SS-G-----------SRGPQPAS-----
------------------------------------------------------------
-------------KDSAEPASSCRTN-------DLSRCPPPAP--ST--SALDPRRPRYQ
TGAWSRQCRIEEEEEVEQELLSQ----SWGREMENG---TVDHSNSSTWHRLHPADGS--
SGQNSKVGTGMSKSASFAFEFPKDRSRTETF-SPPPPPPK--SRHLLKMNKSSSDLEKVS
QSSAESLSPS-FRG-----VHVSFTTSSTDSLASDSRTCSDGGPASEP-----------A
HSPTISG---KKLFAP-VPFPSGSTENVSPSGP-VQPPPLPQKKIVSRAAS-SPDGVFWN
QGSPKPRT---ASPKLNLSHSETNVSVHDEAHFGYFLSTGSRHPPAFS-SEPLEKAFKG-
SAPWVPAPG--LAGSKSSCGSPGLQCRAAPS--TSSSQLSVSSQASSSST-QLQLHSLLS
SISSKEGTYAKLGGLYTQSLARLVAKCEDLFMGGQK-EL-HFNENNW-SLFKLTCNKPCC
D----SGDAIYYCATCSEDPGSTYAVKICKTPEPKT-SSYC-SPSVPVHFNIQQDCGHFV
ASVPSSMLTSP--DT-TRDPL-PAAPAQPPAQEQDCVVVITREVPYQTASDFVRHSAASH
QDDPEA

PF00069 // ENSGT00460000041554_1_Domain_1 (1387, 1623)

YERRVCFLLLQLCNGLEHLKEHGVIHRDLCLENLLLVHCSPQTCPGPSPASA--
-------------------------ASSC-STAVPPSTVTPS-----PLAAPTCQGVPSE
KHLPRLIISNFLKAKQKPGG----TTNLQQKKSQARLAPEIVSASQYRKFDEFQTGILIY
ELLHQPNPFEVRTQLREQDYRQEDLPAIPTLSLYSP---GLQQLAHLLLEADPIKRIRIG
EAKRVLQCLLWGPRRELVEQPGSSEEVLCSTLHNWIDMKRALMMMKFAEKAVDRRRGVEL
EDWLCCQYFAAAEPAALLQSLKLLQLL---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------MTSNCHKGTRPCPSPQPLR--ESLPSEDDSDQRCSPSGDSE
GGEYCSI-LDCCPGTPGAKDAVHATKGSGRH-GGDCSP-MSWEQETCAGSTEE-------
-------EKRVLSFPRE--------CCGQGPTV-NPPRLGPKKPSLNSEAANSSDGLSCG
G-G--SSGASSPLAPHLESDYCSLVKEP-----------APGKQQDSSCRMYTSRKCVGQ
PGELHPPAHPREAVQPEPIYAESTKRKKAVPVPS-RPQAKAEEAAAAQ------GQGQVW
-AGDAWAQKTPSGWGREKEGSEVVPQVAATITVIAAHPEEDHRTIYLSSPDSAVGVQWPR
GPLNQDLE--V------GQEESPA----AQGLSTKESH-----SHNVTENTPKGRPAIPP
KLSKSSPGGSPVSPSA-----SPLTDLSDGS-SG-G----------SSTGPQLSS-----
------------------------------------------------------------
-------------RVPADPTSSCQTNGIA--VSDPAKCPPPTA--SS--SALDQRRPRYH
TGTWSRQCRIEEEEEVEQELLTQ----SWEIEVENG---ALDRSNSSTWHHLHPTDGS--
SGQNSKVSTGMSKSASFAFEFPKDRSRMDAF-SPPPPPPK--SRHLLKMNKSSSDLEKVS
QSSAESLSPS-FRG-----VHVSFTTGSTDSLASDSRTCSDGGPSYEP-----------T
HSPSISG---KQLFAP-VPLLSGSTEDVSPSGP-TQPPPLPQKKIVSRAAS-SPDGFFWT
QGSPKPRT---ASPKLNLSHSETNVCVHDESPFSYSLNSGNHSHHAFS-SEPLEKAFKG-
SVSWTPALG--LVGSKGGCGSPSLQCRAAAS--TSSSQLSVSSQASSNST-QLQLHSLLS
SISSKEGTYAKLGGLYTQSLARLVIKCEDLFMGRQKKEL-HFNENNW-SLFKLTCNKACC
D----SGDAIYYCATCSEDPGSTYAVKICKTPEPKT-ASYC-SPSVPVHFNIQQDCGHFV
ASVPSSMLTST--DTSVKDPL-PAPPPHPPAQEQDCVVVITREVPHQTASDFVRDSVATH
RA

PF00069 // ENSGT00460000041554_1_Domain_1 (1383, 1623)

EPEVYERRVCFLLLQLCNGLEHLKEHGIIHRDLCLENLLLAHCSPQGSPGPSSTAPAI
TTST----------------------SWC-PSG--------L-----PPAALTCQGRPGE
KQLPRLIISNFLKAKQKPGS----TTNLQQKKSQARLAPEIVSASQYRKFDEFQTGILIY
ELLHQPNPFEVRAQLREQDYRREDLPPLPTLSLYSP---GLQQLAHLLLEADPIKRIRIG
EAKRVLQCLLWGPRRELVEQPSISEEALCSTLHNWIDMKRALMMMKFAEKAVDRRRGVEL
EDWLCCQYLASAEPGALLQSLKLLQLF---------

--------------------------------------MSACSDFVEHVWKPGSCKNCFC
LRSDHQLTAGHPKARA-----SSLPA-ITR--LPARPENCRLEDEGV--NGLSYSKPTIA
VKPTMMSSEASDLWTEASLS---AEVPKVSWRRAPGKLPFQK--QEDGPIVYLGSFRGMQ
KSSGALACTD-SNSCCPPAYTMVGLHNLDAQVDRSPAFQPVSFQEEKAGREE--------
-LPSAQESFRQKLAAFAG-MTSSCPKSPRPCPSPQPPR--ESLPSEDDSDQRCSPSGDSE
GGEYCSI-LDCCPESKEAVHSTEG--S--GRRGGDFSP-MCWEQGTCTRPTEE-------
-------EKRLLNLPRE--------CCGQGSTS-NPPRLGPKKPSLNSEAASSSDGLSCG
S-G--SSGASSPFAPHLENDHCSLVKEP-----------VLGKQQDSSCPVITSGKCVGQ
AGELQPPALPREAVQPEPIYAESTKRKKAVPVPS-RPETKAEQVAAGH------SQGQVR
-TGDTWAQKTSSGWSQDREGTNMAPQVATTITVIAAHPEEDHRTIYLSSPDSAVGVQWPH
GPSSQDLQ---A-----GEEESLV----IQGLSSRESH-----PHNVTENTPKEKPAIPP
KLSKSSPGGSPASPAA-----SPLADHSDGNTGS------------SCSGPQLLS-----
------------------------------------------------------------
-------------RVPTNRTSSCQTNGVA--TGDPAKCPPPVTSS----SALDQRRPRYQ
TGAWSRQCRIEEEKEVGQELLSQ----SWGREVENG---NTDHLNSSTWHRLYPT-D-GF
SGQNSKTSSGMSKSASFAFEFPKDRGRMEAF-SPPPPPPK--SRHLLKMNKSSSDLEKVS
QSSAESLSPS-FRG-----AHVSFTTGSTDSLASDSRTCSDGGPSYES-----------A
HSPTISG---KKLFAP-VPFPSGSTEDVSPS-GPAQPPPLPQKKIVSRAAS-SPDGFFWT
QGSPKPPT---ASPKLNVSHSETNVCVHDELPFSYSLNSGDPTHRVFS-SEPLEKAFKG-
SGPWAPALG--LAGSKGGCGSPGLQGRTATS--SSSSQLSVSSQASSSST-QLQLHSLLS
SISSKEGTYAKLGGLYTQSLARLVTKCEDLFMGGQKKEL-RFNENNW-SLFKLTCNKPCC
D----SGDAIYYCATCSEDPGSTYAVKICKTPEPKS-ASYC-SPSVPVHFNIQQDCGHFV
ASVPSSMLASP--DTSSKDNV-QPAPSHSPSQEQDCVVVITREVPHQTASDFVRDSTASH
RA

PF00069 // ENSGT00460000041554_1_Domain_1 (1383, 1623)

EPEVYERRVCFLLLQLCNGLEHLKEHGIIHRDLCLENLLLAHCSPQGSPGPSATPTAP
TTTTTTTT----------------------------TTTSRCP-SATPTATAACQGGPGE
KHLPRLIISNFLKAKQKPGG----TTNLQQKKSQARLAPEIVSASQYRKFDEFQTGILIY
ELLHQPNPFEVRAQLRERDYRREDLPPIPTLSLYSP---GLQQLAHLLLEADPIKRIRIG
EAKRVLQCLLWGPRRELVEQPCTSEEVLCNTLNNWIDMKRALMMMKFAEKAVDRRRGVEL
EDWLCCQYLASAEPGALLQSLKLLQLL---------

-------------------------MHQTLRLNPESPKMSACSDFVEHIWKPGSCKNCFC
LRSDHQLVAGPPQPRE-----GSLPP-PPR--QPSRPENGRLEDEGV--NSSPYSKPTIA
VKPTMMSSEASDVWTEASLS---AEVSQVIWRRAPGKLPLPK--QEDAHVVYLGSFRSVQ
KPAGPSASPDGNA-RCPPAYTMVGLHNLEPHGEKNIAFHPVSFPDEKVGHKEKPSFSYQD
-RPSAQESFRQKLAAFSG-TTSSCHQSPG------PLR--ESLPSEDDSDQRCSPSGDSE
GGEYCSI-LDCCPGSPVAKAASQAAGSRGRHGDRDCSP-TCWEQGRCAGPSEK-------
-------EKQGPSFPRE--------CCGQGPAA-HSSRLGPKKPSLTSEAATSSDGLSCG
SG----SGASSPFIPHLESEYCSLMKEP-----------ALGKQQDPGCLGVASSRCLGP
MGESQPPAHPREATQPEPIYAESTKRKKPTPVPS-KPQAKTEHAATAQGQGQGQGQGQVW
-TGNARAQKTASGWGQDS--PDPAPQVAATITVMAAHPEEDHRTIYLSSPDSAVGVQWPR
GPVSQDSEVGE------EE--TSA----GQGLNSRESH-----AHSASQSKPKGRPAIPP
KLSKNSPGGSPVSPS-----ASPLADLSDGSSSC------------SGIGPQPPS-----
------------------------------------------------------------
-------------GGPAEPAPPCRTNGVT--ISDPSRCPHPAA-----SSALDQRRPRFQ
AGTWSRQCRIEEEEEVEQELLSH----SWGRETKNG---PMDRSNTTTWHRLCPTDGS--
SGQNSKVGTGMSKSASFAFEFPKDRSGIETF-SPPPPPPK--SRHLLKMNKSSSDLEKVS
QGSAESLSPS-FRG-----VHVSFTTGSTDSLASDSRTCSDGGPSSEL-----------A
HSPTNSG---KKLFAP-VPFPSGSTEDVSSSGP-LQPPPLPQKKIVSRAAS-SPDGFFWT
QGSPKPRT---ASPKLNLSHSETN--VHDESHFSYSLSSGNRHHPVFS-SEPLEKAFKG-
SGHWVPAAG--LSGSRSGCGSPGLQCKGAPS--ASSSQLSVSSQASTGST-QLQLHGLLS
SISSKEGTYAKLGGLYTQSLARLVAKCEDLFMGGQKKEL-HFNENNW-SLFKLTCNKPCC
D----SGDAIYYCATCSEDPGSTYAVKICKTPEPKA-VSYC-SPSVPVHFNIQQDCGHFV
ASVPSSMLTSH--DA-PKDPA-PALPAHPPAQEQDCVVVITREVPHQTASDFVRDSAASH
QAEPE

PF00069 // ENSGT00460000041554_1_Domain_1 (1386, 1623)

AYERRVCFLLLQLCNGLEHLKEHGIIHRDLCLENLLLVHCTPPAAPAPAATP---
-------PV----------AAP-----PC-PSGALPAA--PSPA-----AGPACQGGPGE
KQLPRLIISNFLKAKQKPGG----TPNLQQKKNQARLAPEIVSASQYRKFDEFQTGILIY
ELLHQPNPFEVRAQLRERDYRQEDLPPLPPLSLYSP---GLQQLAHLLLEADPIKRIRIG
EAKRVLQCLLWGPRRELVQQPGTSEEALCGTLHNWIDMKRALMMMKFAEKAVDRRRGVEL
EDWLCCQYLASAEPGALLQSLKLLQLL---------

-------------------------MHQTLCLNPESPKMSACSDFVEHIWKPGSCKNCFC
LRSDHQLVAGPPQPRA-----GSLPP-PPR--QPPRPENGRQEDEGV--NSSPYSKPTIA
VKPTMMSSEASDVWTEASLS---AEVSQVIWRRAPGKLPLPK--QEDAHVVYLGSFRSVQ
KPTGPSASPDGNA-RCPPAYTMVGLHNLEPHGEKNIAFHPVSFPDEKVGHKEKPSFSYQD
-RPSAQESFRQKLAAFSG-ATSSCHQSPG------PLR--ESLPSEDDSDQRCSPSGDSE
GGEYCSI-LDCCPGSPVAKAASQAAGSRGRHGDRDCSS-TCWERGKCAGPSEQ-------
-------EKRGPSFPRE--------CCSQGPTA-HSSRLGPKKPSLTSEAATSSDGLSCG
SG----SGTSSPFIPHLESEYCSLMKEA-----------APGKQQDPGCPGVASSRCLGP
MGESQPPAHPREATQPEPIYAESTKRKKPTPVPS-KPQAKTEHAAAA------QGQGQVW
-TGNAWAQKTASGWGQDS--PDPAPQVAATITVMAAHPEEDHRTIYLSSPDSAVGVQWPR
VPVSQDSEVGE------EE--TSA----GQGLNPRESH-----AHSASESKPRGRPAIPP
KLSKSSPGGSPASPS-----ASPLADLSDGSSGS------------SGTGPQPPS-----
------------------------------------------------------------
-------------RGPAEPAPPCRTNGVT--ISDPSRCPLPAA-----SSALDQRRPRLQ
AGTWSRQCRIEEEEEVEQELLSH----SWGRETKNG---PTARSNTTTWHRLCPTNGS--
SGQNSKVGTGMSKSASFAFEFPKDRSGIETF-SPPPPPPK--SRHLLKMNKSSSDLEKVS
QGSAESLSPS-FRG-----VHVSFTTGSTDSLASDSRTCSDGGPSSEL-----------A
HSPTNSG---KKLFAP-VPFPSGSTEDVSSSGP-LQPPPLPQKKIVSRAAS-SPDGFFWT
QGSPKPRT---ASPKLNLSHSETN--VHDESHFSYSLSSGNRHHPVFSSSEPLEKAFKG-
SGHWVPAAG--LSGSRSGCGSPGLQCKGAPS--ASSSQLSVSSQASTGST-QLQLHGLLS
SISSKEGTYAKLGGLYTQSLARLVAKCEDLFMGGQKKEL-HFNENNW-SLFKLTCNKPCC
D----SGDAIYYCATCSEDPGSTYAVKICKTPEPKT-VSYC-SPSVPVHFNIQQDCGHFV
ASVPSSMLTAH--DA-PKDPV-PALPAHPPAQEQ

PF07714 // ENSGT00460000041554_1_Domain_0 (1355, 1423)

DCVVVITREVPHQTASDFVRDSAASH
QAEPEAYERRVCFLLLQLCNGLEHLKEHGIIHRDLCLENLLLVHCTXXXXXXXXXXXX--
-------XX----------XXX-----XX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXX----TPNLQQKKNQARLAPEIVSASQYRKFDEFQTGILIY
ELLHQPNPFEVRAQLRERDYRQEDLPPLPALSLYSP---GLQQLAHLLLEADPIKRIRIG
EAKRVLQCLLWGPRRELVQQPGTSEEALCCTLHNWIDMKRALMMMKFAEKAVDRRRGVEL
EDWLCCQYLASAEPGALLQSLKLLQLL---------

--------------------------------------MSACSDFVEHIWKPGSCKNCFC
LRSDHQPTTGHPKARA-----NSLPA-GTR--LPARPENCRLDDEGV--NGLAYSKPTIA
VKPTMMTSETSDLWTEASLS---AEVPKVNWRRTPGKLLLPK--QEDEPIVYLGSFRGLQ
KPASPLACTD-GNSRCPPAYTMVGLHNLEARVDRNTAFQPVSFQEEKAGREE--------
-LPSAHESFRQKLAAFAG-MTSSCPKGPRPCTSPQPLR--ESLPSEDDSDQRCSPSGDSE
GGEYCSI-LDCCPESKDAVHSTEG--S--GRRGGDCSP-MCREQGPRTRPTEE-------
-------EKQGLSFPRE--------CCGQGSTA-NPPRLGPKKPSLNSEAASSSDGLSCG
S-S--RSGASSPFAPHLENDYCSLVKEP-----------ASGKQQDLSGHFLTSGKCVGQ
AAELQPASLLRDPVQPEPIYAESAKRKKAAPGPP-RPEPKKEQVPAGH------SQGQVW
-TGDTWIQKTTPSWSQDREGANPAPQVATTITVIAAHPEEDHRTIYLSSPDSAVGVQWPR
H-SNQDLQ---A-----SEEEPLV----VQGLTSRESH-----PHNVTENTSKEKPAIPP
KLSKSSPGGSPVSPAA-----PPLTDHSDGNTGG------------SSVGPQLLS-----
------------------------------------------------------------
-------------RVPANLTSSCHTNGVAT-ASDTAKCPPPATSS----SVLDQRRPRYQ
TGAWSRQCRIEEEEEVGQEL-SQ----SWGRELENG---TADHSNSSTWHRLHPI-D-GT
SGQNSKTNSGMSKSASFAFEFPKDRGRLEAF-SPPPPPPK--SRHLLKMNKSSSDLEKVS
QSSAESLSPS-FRG-----AHVSFTTGSTDSLASDSRPCSDGGPSYEP-----------T
HSPTISG---KKLFAP-VPFPSGSTEDVSPGGGPAQPPPLPQKKIVSRAAS-SPDGFFWT
QGSPKPRT---ASPKLNLSHSETNVCAHDESPFNCSLNSGNRSHHVFSSSEPLEKAFKG-
NAPWAPALG--LANSKGGCGSPSLQCRTATS--TSSSQLSVSSQASSSST-QLQLHSLLS
SISSKEGTYAKLGGLYTQSLARLVTKCEDLFMGGQKKEL-RFNENYW-SRFKLTCNKPCC
D----SGDAIYYCATCTEDPGSIYAVKICKTPEPKS-ASYC-SPSVPVHFNIQQDCGHFV
ASVPSSMLAS--PDTSSKDTA-PAVSPQPPAQEQDCVVVITREVPHQTASDFVRDSMASH
RA

PF00069 // ENSGT00460000041554_1_Domain_1 (1383, 1623)

EPEVYERRVCFLLLQLCNGLEHLKEHGIIHRDLCLENLLLAHCNPQSSPGPSATPTVP
T------------------------------------TTSRCP-SAVPAATTACQGGPGE
KQLPRLIISNFLKAKQKPGG----TTNLQQKKSQARLAPEIVSASQYRKFDEFQTGILIY
ELLHQPNPFEVRAQLRERDYRREDLPPLPTLSLYSP---GLQQLAHLLLEADPIKRIRIG
EAKRVLQCLLWGPRRELVEQPCPSEEVLCNTLHNWIDMKRALMMMKFAEKAVDRRRGVEL
EDWLCCQYLASAEPGALLQSLKLLQLL---------

--------------------------------------MSACSDFVEHIWKPGSCKNCFC
LRSDHQLAGGRTQPRT-----GSLPA-PPR--PPPRS----VEDEGV--NGSPYCKPTIA
VKPTMMSSEASDLWTEASLS---AEVPQVIWRRAPGKLSLPK--QEDVPIVYLGSFRGVQ
KPAGPSACTD-GSSHCPPAYAMVGLHSLQARGERNLAFHPVGFPDEK-------------
-LPSAQESFRQKLAAFAE-MTSGCHKGPRPCPSPQPLQ--ESLPSEDESDQRCSPSGDSE
GGEYCSI-LDCCPRSPATKDIVHTEGSQGRCEG-GNSS-MCWEQGTSTEPPEE-------
-------EKRSLSFPRD--------CCDQGPSA-NPPHLGPKKLSANSEAA-SSDGLSCG
S-G--SSGASSPFAPHLENDYCSLVKEA----------VLPGKQQDSDCHVVTSTRCP--
--ESQPPAHPREAAQPEPIYAESTKRKKAVSVPS-RPQAKQAPA----------TQSQVW
-TGDVRAQKTPSVWNRDREGSDMAPPVAATITVMAAHPEEDHRTIYLSSPDSAVGVQWPQ
GPVGQDVE--A------GEEETIA----GQRLSSKESH-----PHDRSENVPKGRPAIPP
KLSKSSPGGSPASPSA-----SALADSSEG-NS--G-----------SRAPQSTC-----
------------------------------------------------------------
-------------RGSADPTTSCWTN-------DPTRCPPPAA--ST--SALDQRRPRYQ
TGAWSRQCRIEEEEEVEQELLGQ----SWGREMDNG---TVDHSNSSTWHRLHPTDVS--
SGQNSKVRTGMSKSASFAFEFPKDRSRMEAF-SPPPPPPK--SRHLLKMNKSSSDLEKVS
QGSAESLSPS-FQG-----VPISFTTSSTDSLASDSRTCSDGGPSSEP-----------T
HSPTLSG---KKLFAP-VPFPLGSTENVSPSGP-VQPPPLPQKKIVSRAAS-SPDGVFWT
HGSPKPRT---GSPKLNLSHSETNVSTHDESHLSCSMSPRNRHHPVFSSSEPLEKAFKG-
SGHWVPALG--LAGSKSSCGSPSLQCKTAAS--TSSSQLSVSSQASSSST-QLQLHSLLS
SISSKEGTYAKLGGLYTQSLARLVAKCEDLFIGGQKKEL-HFNENNW-SLFKLTCNKPCC
D----SGDAIYYCATCSEDPSSTYAVKICKTPEPKT-ASYC-SPSVPVHFNIQQDCGHFV
ASVPSSMLSSP--DT-TKDPL-PAAPSQPPAQEQDCVVVITREVPYQTASDFVRDSAASH
QAAPE

PF00069 // ENSGT00460000041554_1_Domain_1 (1386, 1623)

VYERRVCFLLLQLCNGLEHLKEHGIIHRDLCLENLLLVHCGLQASPGPSPANPSL
A----------------------G----------PPSTVAPG-----SLTAPAYRGVPSE
KHLPRLIISNFLKAKQKPGG----TTNLQQKKSQARLAPEIVSASQYRKFDEFQTGILIY
ELLHQPNPFEVRAQLREQDYRQEDLPPLPTLSLYSP---GLQQLAHLLLEADPIKRIRIG
EAKRVLQCLLWGPRRELVEQPSPSEEVLCSTLHNWIDMKRALMMMKFAEKAVDRRRGVEL
EDWLCCQYLAAAEPTVLLQSLKLLQLL---------

--------------------------------------MSACNDFVEHIWKPGSCKNCFC
LRSDHQLAIGHPQSRT-----GSLPP-PPR--LPPRPENCRLDDDG-----SPYSKPTIA
VKPTMMSSEASDVWAEASLS---AEVSQVIWRRAPSKLPLPK--QDDVPIVYLGSFRGVQ
KPAGPVACTE-GSSHCPPAYAMVGLHSLD-QGERSIAFHPVSYPEEKARREE--------
-LSSAQESFRQKLAAFSG-MTSGCHKGPRPCPSPQPLR--ASLPSEDDSDQRCSPSGDSE
GGEYCSI-LDCCPGSPVAKDTMNAEGSLGRHGGGDCSP-TCWEQGMCAQPGQE-------
-------EKRVLNFPRE--------FCGQGPTT-NPPHLVSKKLTS---EAASSDGLSCG
S-S---SGTSSPFTPHLESDYCSLMKEP-----------VPGKQQDSGCHVMTSNKCLGL
AVEPQSPAQPREAVQPEPIYAESTKRKKAVPVPS-RPQAKAEQATAAPGQTH--G-HQAW
-AGDTWAQKIPSGWSRDKEGPDKAPQVATTITVMAAHPEEDHRTIYLSSPDSAVGVQWPH
GPVNQDLE--A------GTEETSA----RQGPSSRESQ-----AHGLTETTPRGRPAIPP
KLSKSSPGGSPASPSA-----LTLADVGDGSSNG-S-----------GSGSQLSS-----
------------------------------------------------------------
-------------RGPAELTASCRANSAT--VSEPARCPPA-V--SS--SAVDQRRPKYQ
TGAWS---RIEEEEEVEQELLNQ----SWGRKTENG---TAALSNSSTWHRLHPSDGS--
SGQNGKVGTGMSKSASFAFEFPKDRSGLETF-SPPPPPPK--SRHLLKMNKSSSDLEKAS
QGSAESLSPS-FRS-----VHVSFTSGSTDSLASDSRTCSDGGPSYEP-----------T
HSPTISG---KKLFAP-VPFPSGSTEDVCPSGP-AQPPPLPQKKIVSRAAS-SPDGFFWT
QGSPKPRT---ASPKLNLSHSETNVCVHDDAPFSYSLSSGNRHPHVFSSSEPLEKAFKG-
NGHWVPASG--LASPKSDCVNPNFQCTVAVT--TSSSQLSVASQASSGST-QLQLHSLLN
SISSKEGTYAKLGGLYTQSLARLVAKCEDLFMGGQKREL-HFNENNW-SLFKLTCNKPCC
D----SGDAIYYCATCSEDPGSTYAVKICKTPEPKT-ASYC-SPSVPVHFNIQQDCGHFV
ASVPSSMLTSP--DA-SKDPL-PALPSHLPSQEQDCVVVITREVPHQTASDFVRDSVASH
SA

PF00069 // ENSGT00460000041554_1_Domain_1 (1383, 1623)

EPEVYERRVCFLLLQLCNGLEHLKEHGIIHRDLCLENLLLVHCSPQASPGLPSASPAP
LAPTTI-------------------------PTPAPASGPPG-----PAAVPACQAAPGE
KQLPRLIISNFLKAKQKPGG----TSNLQQKKSQARLAPEIVSASQYRKFDEFQTGILIY
ELLHQPNPFEVRAQLREQDYRREDLPPLPTLSLYSP---GLQQLAHLLLEADPIKRIRIG
EAKRVLQCLLWGPRRELVEQPATSEEALCSTLHNWIDMKRALMMMKFAEKAVDRRRGVEL
EDWLCCQYLAAAEPGALLQSLKLLQLL---------

------------------------------------------------------------
-----------PPPRA-----GSQ-P-PPR--LPPRPENCRLEDEGV--NSSPYCKPTIA
VKPTMMSSEASDVWTEAGIG---AEVSQVIWRRVPSKLSLPLAKQDDTPMVFLGGVRGP-
----------CGHARSPPGYAMVGLPSPEPRAERSLAFHPMGFTSEKARQEEKASFPYQE
-LPPTXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXX----XXXX
XXXXXXX-XXXXXXXXXXXXX-XXXXXXXXXXXXXXXX-XXXXXXXX-XX--X-------
-------XXXXXXXXXX--------XXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXX
X-X--XXXXXXXXXXXXXXXXXXXXXXX-----------XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXX---X--XXXXXX
-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXX--XX-----XXXXXXX----XXXXXXXXXX-----XXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXX-----XXXXXXXXXXXXX-X-----------XXXXXXXX-----
------------------------------------------------------------
-------------XXXXXXXXXXXXXXXX--XXXXXXXXXXXX--XX--XXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXX----XXXXXXXXX---XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXX--XXH-LTIEKSRFVXXXXX
XXXXXXXXXX-XXX-----XXXXXXXXXXXXXXXXXXXXXXXXPSYEP-----------T
HSPTGSG---KKLFAP-VPFPSGSTEDVSPTGP-LRPPPLPQKKIVSRAAS-SPDGFFWT
QGSPKPRA---SSPKLNLSHSETSVCVHEESHLSHPLGSGKHHHYVFSSSEPLEKAFKG-
SGHWGPAPGL-----RGGCGSPSLQGRGAPS--TSSSQLSVSSQASTSST-HLQLHSLLS
SISSKEGTYAKLGGLYTQSLARLVAKCEDLFMDGQKKEL-HFNENNW-SLFKLTCNRPCC
D----SGDAIYYCATCSEDPGSTYAVKICKTPEPKA-ASYC-SPSVPVHFNIQQDCGHFV
ASVPSSMLAPP--EA-PKDPL-PTLPSHTPAQEQDCVVVITREVPHQTALDFVRDSVASH
RAEPEAYERRVCFLL

PF07714 // ENSGT00460000041554_1_Domain_2 (1396, 1422)

LQLCNGLEHLKEHRVIHRDLCLENLLLVHCAPPAASPAPAPGPAP
-G-------------------P-TATPPG-PSAAFPASTAPS-----PAAAPACQGVPSD
KQLPRLIISNFLKAKQKPGS----ATNLQQKKSQARLAPEIVSASQYRKFDEFQTGILIY
ELLHQPNPFEVRAQLREQDYRQEDLPSLPALSLYSP---GLQQLAHLLLEADPIKRIRIG
EAKRVLQCLLWGPRRELVGQPGASEETLCSMLHNWIDMKRALMMMKFAEKAVDRRRGVEL
EDWLCCQYLASAEPAALLQSLKLLQLL---------

--------------------------------------MSACSDFVEHIWKPGSCKNCFC
LRSDHQLAAGGPQPRT-----GSLPP-PPR--LPPKS----VEDEGV--NGSPYCKPTIA
VKPTMMSSETSDVWTEASLS---AEVPQVIWSRAHGKLPLPK--QEDVPIVYLGSFRGVQ
KPAGPSACTD-GSSHCPPAYAMVGLHSLQARGERNMAFHPVGFPDEK------------E
-LPSAQESFRQKLAAFAE-MTSSCHKSPRPCPSPQPVQ--ESLPSEDESDQRCSPSGDSE
GGEYCSI-LDCCPRSLAAKDPTHVESLQGRCGGGSSSP-MCWEQGTRAGPPEE-------
-------EKQSPSFPRE--------CCGQGPSA-NPPHLGPQKPSLSSEAASSSDGLSYG
S-S--SSGASSPFTPHLESDYCSLVKEA----------VLPGKQQDSVCHVVTSSRCS--
--ESQPPAQPREAAQPEPIYAESSKRKKAVPVPS-RPQAKAEQATAA--------QGQVW
-TSDARAQKTPSVWSRDREGSDMAPQVSTTITVMAAHPEEDHRTIYLSSPDSAVGVQWPR
GPVGQDLE--A------GKEETVS----GHGPSSKESH-----PHGRAENMPKGRPAIPP
KLSKSSPGS-PASRAA-----SPLANPAEG--SP-G-----------SRGPQPAS-----
------------------------------------------------------------
-------------KDSAEPASSCRTS-------DLSRCPPPAP--ST--SALDPRRPRYQ
TGAWSRQCRIEEEEEVEQELLSQ----SWGREMENG---TADHSNSSTWHRLHPADGS--
SGQNSKVGTGMSKSASFAFEFPKDRSRTETF-SPPPPPPK--SRHLLKMNKSSSDLEKVS
QSSAESLSPS-FRG-----VHVSFTTSSTDSLASDSRTCSDGGPASEP-----------A
HSPTISG---KKLFAP-VPFPSGSTENVSPSGP-VQPPPLPQKKIVSRAAS-SPDGVFWN
QGSPKPRT---ASPKLNLSHSETNVSVHDEAHLGYFLSTGSRHPPAFS-SEPLEKAFKG-
SAPWGPAPG--LAGSKSSCGSPGLQCRAAPA--TSSSQLSVSSQASSSST-QLQLHSLLS
SISSKEGTYAKLGGLYTQSLARLVAKCEDLFMGGQK-EL-HFSENNW-SLFKLTCNKPCC
D----SGDAIYYCATCSEDPGSTYAVKICKTPEPKT-SSYC-SPSVPVHFNIQQDCGHFV
ASVPSSMLTSP--DA-TRDPL-PAAPAQPPAQEQDCVVVITREVPYQTASDFVRHSAASH
QDDPEA

PF00069 // ENSGT00460000041554_1_Domain_1 (1387, 1622)

YERRVCFLLLQLCNGLEHLKEHGVIHRDLCLENLLLVHCSPQTCPGP-------
------------------------------------------------LAAPTCQGVPSE
KHLPRLIISNFLKAKQKPGG----TTNLQQKKSQARLAPEIVSASQYRKFDEFQTGILIY
ELLHQPNPFEVRTQLREQDYRQEDLPAIPTLSLYSP---GLQQLAHLLLEADPIKRIPIG
EAKRVLQCLLWGPRRELVEQPGSSEEVLCSTLHNWIDMKRALMMMKFAEKAVDRRRGVEL
EDWLCCQYFAAAEPAALLQSLKLLQLL---------

-------------------------MHQTLLLKPESLKMSACSDFVEHIWKPGSCKNCFC
LRSDHQLVADPPQPRA-----GSLPP-PPR--LPPRPENCRLEDEGV--NSSPYSKPTIA
VKPTMMSSEASDVWTEASLS---AEVSQVIWRRAPGKLPLPK--QEDAPVVYLGSFRGVQ
KPAGPSASPDGNSPRCPPAYTMVGLHNLEPRGERNIAFHPVSFPDEKAGHKEKPSFPYQD
-RPSTQESFRQKLAAFAG-TTSGCHQGPG------PLR--ESLPSEDDSDQRCSPSGDSE
GGEYCSI-LDCCPGSPVAKAASQAAGSRGRHSGRDGSP-TCWEQGKCAGPTEQ-------
-------EKRGLSFPKE--------CCSQGPTA-HPSCLGPKKASFTSEAATSSDGLSCG
SG----SGASKPFVPHLESDYCSLMKEP-----------APEKQQDLGCPGVASSRCLGL
TGEPQPPAHPREATQPEPIYAESTKRKKAAPVPS-KPQAKTEHAAAAQGQGHSQGQGQVW
-TGNAWTQKTASGWGQDS--PDPTPQVAATITVMAAHPEEDHRTIYLSSPDSAVGVQWPR
GPVSQNSEVGE------EE--TLA----RQGLSSRESH-----AHSANESKPKERPAIPP
KLSKSSPGGSPVSSSAGGPPVSPLADLSDGSSGS------------SGIGHQPPS-----
------------------------------------------------------------
-------------RGPADPVPPCRTNGVT--LSDPSRCPQPVT-----SSALDQRRPRFQ
AGTWSRQCRIEEEEEVEQELLSH----SWGRETKNG---PTDHSNSTTWHRLPPTDGS--
SGQNSKVGTGMSKSASFAFEFPKDRSGIETF-SPPPPPPK--SRHLLKMNKSSSDLEKVS
QGSAESLSPS-FRG-----VHVSFTAGSTDSLASDSRTCSDGGPSSEL-----------A
HSPTNSG---KKLFAP-VPFPSGSTEDVSPSGP-LQPPPLPQKKIVSRAAS-SPDGFFWT
QGSPKPQT---ASPKLNLSHSETN--VHDESHFSYSLSPGNRHHAVFSSSDPLEKAFKG-
SGHWVPVAG--LAGNRGGCGSPGLQCKGTPS--ASCSQLSVSSQASTGST-QFQLHGLLS
NISSKEGTYAKLGGLYTQSLARLVAKCEDLFMGGQKKEL-HFNENNW-SLFKLTCNKPCC
D----SGDAIYYCATCSEDPGSTYAVKICKTPEPKT-VSYC-SPSVPVHFNIQQDCGHFV
ASVPSSMLTSP--DA-PKDPV-PALPAHPPAQEQDCVVVITREVPHQTASDFVRDSTASH
QAQPE

PF00069 // ENSGT00460000041554_1_Domain_1 (1386, 1622)

AYERRVCFLLLQLCNGLEHLKEHGIIHRDLCLENLLLVHCTPAAAPGPTPAT---
-------------------AAP-----PC-SSAALPAGGTLGPA-----AGPASPEGPRE
KQLPRLIISNFLKAKQKSGG----TPNLQQKKSQARLAPEIVSASQYRKFDEFQTGILIY
ELLHQPNPFEVRAQLRERDYRQEDLPPLPALSLYSP---GLQQLAHLLLEADPIKRIRIG
EAKCVLQCLLWGPRRELVQQPGTSEEALCGTLHNWIDMKRALMMMKFAEKAVDRRRGVEL
EDWLCCQYLASAEPRALLQSLKLLQLL---------

-------------------------MHQTLRLNSESPKMSACSDFVEHIWKPGSCKNCFC
LRSDHQLVAGPPQPRA-----GSLPP-PPR--LPPRPENCRLEDEGV--NTSPYSKPTIA
VKPTMMSSEASDVWTEANLS---AEVSQVIWRRAPGKLPLPK--QEDASVVYLGSFRGVQ
KPAGPSTSPDGNS-RCPPAYTMVGLHNLEPRGERNIAFHPVRFPDEKAGHKEKPSFPYQD
-RPSTQESFRQKLAAFAG-TTSGCHQGPG------PLR--ESLPSEDDSDQRCSPSGDSE
GGEYCSI-LDCCPGSPVAKAASQTAGSRGRHGGRDCSP-TCWEQGKCSGPAEQ-------
-------EKRGPSFPKE--------CCSQGPTA-HPSCLGPKKLSLTSEAAISSDGLSCG
SGSGSGSGASSPFVPHLESDYCSLMKEP-----------APEKQQDPGCPGVTPSRCLGL
TGEPQPPAHPREATQPEPIYAESTKRKKAAPVPS-KSQAKIEHAAAAQGQGQGPGQGQVC
-TGNAWAQKTASGWGRDS--PDPTPQVSATITVMAAHPEEDHRTIYLSSPDSAVGVQWPR
GPVSQNSEVGE------EE--TSA----GQGLSSRQSH-----AHSASESKPKERPAIPP
KLSKSSPVGSPVSPSAGGPPVSPLADLSDGSSGG------------SSIGPQPPS-----
------------------------------------------------------------
-------------QGPADPAPSCRTNGVT--ISDPSRCPQPAA-----SSASEQRRPRFQ
AGTWSRQCRIEEEEEVEQELLSH----SWGRETKNG---PTDHSNSTTWHRLHPTDGS--
SGQNSKVGTGMSKSASFAFEFPKDRSGIETF-SPPPPPPK--SRHLLKMNKSSSDLEKVS
QGSAESLSPS-FRG-----VHVSFTTGSTDSLASDSRTCSDGGPSSEL-----------A
HSPTNSG---KKLFAP-VPFPSGSTEDVSPSGP-LQPPPLPQKKIVSRAAS-SPDGFFWT
QGSPKPRT---ASPKLNLSHSETN--VHDESHFSYSLSPGNRHHPVFSSSDPLEKAFKG-
SGHWLPAAG--LAGNRGGCGSPGLQCKGAPS--ASSSQLSVSSQASTGST-QLQLHGLLS
NISSKEGTYAKLGGLYTQSLARLVAKCEDLFMGGQKKEL-HFNENNW-SLFKLTCNKPCC
D----SGDAIYYCATCSEDPGSTYAVKICKTPEPKT-VSYC-SPSVPVHFNIQQDCGHFV
ASVPSSMLSSP--DA-PKDPV-PALPAHPPAQEQDCVVVITREVPHQTASDFVRDSAASH
QAEPE

PF00069 // ENSGT00460000041554_1_Domain_1 (1386, 1623)

AYERRVCFLLLQLCNGLEHLKEHGIIHRDLCLENLLLVHCTLQAGPAPAP-----
---APAPAA----------AAP-----PC-SSAAPPAGGTLSPA-----AGPASPEGPRE
KQLPRLIISNFLKAKQKPGG----TPNLQQKKSQARLAPEIVSASQYRKFDEFQTGILIY
ELLHQPNPFEVRAQLRERDYRQEDLPPLPALSLYSP---GLQQLAHLLLEADPIKRIRIG
EAKRVLQCLLWGPRRELVQQPGTSEEALCGTLHNWIDMKRALMMMKFAEKAVDRRRGVEL
EDWLCCQYLASAEPGALLQSLKLLQLL---------

-------------------------MLETIPLNPESPKMSACSDFVEHIWKPGSCKNCFC
LRSDHQLVPGRPQPRA-----GCLPP-PPR--LHPRPESGRPEDDSL--SGSPYSKPTIA
VKPTMMSSEASDGWTEAGVS---ADVAQVIWRRAPGKLPVPK--QEDAPVVYLGSFRGVQ
KPAGPSGPKDRGHPRNPPAYAMVGLHSLEPRGDRSAAFHPVSFPDEKLGRDDKPVIPYQE
-LNSPQESFRHKLAAFSG-MTSGCHKGLGPYPSAQPLR--ESLPSEDDSDQRCSPSGDSE
GGEYCSI-LDCCPGSPGAEDAARSGGSRHRQGGRDCSA-ACWEPRVCARPPEE-------
-------EKRALSFPRD--------CCSQGPTE-STPHLGPKKQSLASEAASSSDGLSCG
S-A--NSRASSPLAPHPESDYCSLRKEP-----------GPGKQQDSGCHGVASSRCPGQ
TGEPQPPAHSREAAQSEPIYAESTKRKKAVPVPS-RLQAKAEQGAGTP------GQAQVR
-TVNTRAQKAASGCGQDREGPEVAPKMAATITVMAAHPEEDHRTIYLSSPDSSVGVQWPR
GPPSQQAP--EA-----GGEEPSA----GQGLGSRESR-----HRSASETTAKGRPAIPP
KMSRSSPGGSPVSPSA-----SPLSDLSEGNSG--------------IPGPQPPS-----
------------------------------------------------------------
-------------RAPADPASSCRANGIP--ASDSARGPPPATST----SVLEQRRPRPQ
AGAWSRQCRIEEEDEVEQDLLSQ----SWGREVENG---PLDPASSSAWHRLCSTDG---
SGQNSKAGTGMSKSASFAFEFPKDRSGIEVF-SPPPPPPK--SRHLLKMNKSSSDLEKVS
QGSAES-----LRG-----VHVSFTTGSTDSLASDSRTCSDGGPSSEP-----------A
HSPTNSR---KKLFAP-VPFPSGSTEDVSPGDP-LQPPPLPQKKLVSRAAS-SPDGFFWP
QGSPKPRT---ASPKLNLSHSETNVCAHEDSHFSYASGPGGRHQHVFSASEPLEKTSKG-
SGHRGPTPG--LG------GSKGLQGKGVSS--TSSSQLSVSSQASAGST-QLQLHSLLN
SISSKEGTYAKLGGLYAQSLVRLVARCEDLFMGGQKKEL-HFSENNW-SLFKLTCNKPCC
D----SGDAIYYCATCSEDPGSTYAVKICKTPEPKA-ASYC-SPSVPVHFNIQQDCGHFV
ASVPSSMLTSP--DA-HKDPL-SALPSHPPAQEQDC

PF07714 // ENSGT00460000041554_1_Domain_0 (1357, 1423)

VVVITREVPHQTASDFVRDLATSH
QSEPEVYERRVCFLLLQLCNGLEHLKEHGIIHRDLCLENLLLVHCAPQASPEPSPAASVP
PTT--------------TSPAPAATPSSG-PSATVPTSVTPT-----PPAAPAFQGGSSE
KHLPRLIISNFLKAKQKPGG----TANLQQKKSQARLAPEIVSASQYRKFDEFQTGILIY
ELLHQPNPFEVRAQLREQDYRQEDLPPLPALSLYSP---GLQRLAHLLLEADPIKRIRIG
EAKRVLQCLLWGPRRELVEPPGTSEEALCATLHNWIDMKRALMMMKFAEKAVDRRRGVEL
EDWLCCQYLASAEPAALLQSLKLLQLL---------

-------------------------MHQTLRLKPESLKMSACSDFVEHIWKPGSCKNCFC
LRSDHQLVAGPPQPRA-----GSLPP-PPR--LPPRPENCRLEDEGV--NSSPYSKPTIA
VKPTMMSSEASDVWTEASLS---AEVSQVIWRRAPGKLPLPK--QEDAPVVYLGSFRGVQ
KPAGPSTSPDGNSPRCPPAYTMVGLHNLEPRGERNIAFHPVSFPDDKAGHKEKPSFPYQD
-RPSAQESFRQKLAAFAG-TTSGCHQGPG------PLR--ESLPSED--DQRCSPSGDSE
GGEYCSI-LDCCPGSPVAKAASQAAGSRGRHSGRDGSP-TCWEQGKCAGPTEQ-------
-------EKRGPSFPKE--------CCSQGPTA-HPSCLGPKKASFTSEAATSSDGLACG
SGSGSGSGASNPFVPHLESDYCSLMKEP-----------APEKQQDLGCPGVASSRCLGL
TGEPQPPAHPREATQPEPIYAESTKRKKAAPVPS-KPQAKTEHAAAAQ------GQGQVW
-TGNAWAQKTASGWGQDS--PDPTPQVAATITVMAAHPEEDHRTIYLSSPDSAVGVQWPP
GPGSQNSEVGE------EE--TLA----RQGLSSRESH-----AHSAKESKPKERPAIPP
KLSKSSPGGSPVSPSAGGPPVSPLADLSDGSSGS------------SGIGPQPPS-----
------------------------------------------------------------
-------------RGPADPVPPCRTNGVT--LSDPSRCPQPVT------SALDQRRPRFQ
AGTWSRQCRIEEEEEVEQELLSH----SWGRETKNG---PTDHSNSTTWHRLHATDGS--
SGQNSKVGTGMSKSASFAFEFPKDRSGIETF-SPPPPPPK--SRHLLKMNKSSSDLEKVS
QSSAESLSPS-FRG-----VHVSFTTGSTDSLASDSRTCSDGGPSSEL-----------A
HSPTNSG---KKLFAP-VPFPSGSTEDVSPSGP-RQPPPLPQKKIVSRAAS-SPDGFFWT
QGSPKPQT---AGPKLNLSHSETN--VHDECHFSSSLSPGNRHHAVFSSSDPLEKAFKG-
SGHWVPAAG--LAGNRGGCGSPGLQCKGTPS--ASSSQLSVSSQASTGST-QFQLHGLLS
NISSKEGTYAKLGGLYTQSLARLVAKCEDLFMGGQKKEL-HFNENNW-SLFKLTCNKPCC
D----SGDAIYYCATCSEDPGSTYAVKICKTPEPKT-VSYC-SPSVPVHFNIQQDCGHFV
ASVPSSMLTSP--DA-PKDPV-PTLPAHPPAQEQDCVVVITREVPHQTASDFVRDSAASH
QAEPE

PF00069 // ENSGT00460000041554_1_Domain_1 (1386, 1623)

AYERRVCFLLLQLCNGLEHLKEHGIIHRDLCLENLLLVHCTPQAAPGPTPAT---
-------------------AAP-----PC-SSAALPAGGTLSPA-----AGPASPEGPRE
KQLPRLIISNFLKAKQKPGG----TPNLQQKKSQARLAPEIVSASQYRKFDEFQTGILIY
ELLHQPNPFEVRAQLRERDYRQEDLPPLPALSLYSP---GLQQLAHLLLEADPIKRIRIG
EAKRVLQCLLWGPRRELVQQPGTSEEALCGTLHNWIDMKRALMMMKFAEKAVDRRRGVEL
EDWLCCQYLASAEPGALLQSLKLLQLL---------

--------------MQNEHWRAVQKTKWALSLTHEDLKMSACSDFVEHVWKPGSCKNCFN
PKSSHQLQTPADVGAC-----GVLP-----DGARTKSESLVLEDEGV--NTFHFSKPTIA
VKPTTINSDVSNTWADTNMN---ADLSQVRWGMISGKQLLLKSGDAQRICLDNFANDGVR
QPFLHNQPND-CLSCCPPRYSMVGLHGLESRVERSVSIHSLVLVGEVGKQEDGVKDKFA-
-LP--HQVPCPNLSALGDRSTTNSSKNTS----SQ--ARGVVLPSGCDCG-HISSIFESE
GGEYCSI-TNYLKEHPVPWKPCCTEEKAAQCE-ESHIP-SGRKQQDALEIPRPSSRAVKF
SEEEHRAVNTAFCATED-----------QSDPLPYAFCLDKKNLSLHTKLATLPKSTG--
------SCKAAALALSQEDEDLPLTGEPF---------------VTAGLCTESSSTPQEA
LVEPQCPR-LTEPAHGDPIYAESTKRRKAQLKAV-GSQAKTEKLAHSTAKEK--------
-ADGLW-RDGGWISGGEKEHQDSTGQVAAKITIMTAHTEDDHKTIFLSSPDSAVGVQWPY
ISPTSHPDFGTSSPAIESGQIFQAS----GYENSTRFH-----LAAPVKTSVSESPAIPP
KMSKNSQPGSEGRHVS--PVSSHMGRFGDDNSHDGA-------------GVQLLP-----
--------RSYTDTDA--------------------------------------------
--------------FGVTPSPSTHVNGVS-----------VEESSRGVAGPSYDRRQKYC
NPMWTKQCRIEEEE------EQGVLNHPWTVGAASGRTGS----------------GFVD
DGPILKSQIGMTKSSSFSFDFPKDKSNGVEF-APPPPPPKKQSR--LKMNPSNTELETVS
NSSAESLSPP-FRS-----GHISFTAGSSDSLNSDTQTGSDGRHSSEP-----------N
HSPPPAA---SQVLPP-VPFLSVSTVDGSSSAP-SCPPPLPQKKTVIRTVS-SPDGFFGG
QASSGKAA-GAASPRLNVSHSESNVCLGEEPLFTHLASLGDR-PGTFSSSESLEKRSKG-
NSYWGSNTGK-----STGACGPSR---NLQS--LSSSQLSVSSQVSSACS----LHNLLS
NIDSKEGVYSKLGALYAESLRRLVTKCEDCFMREQKNEL-HFSENNW-SLFKLTCNKPCC
D----SGDAIYYCATCSKDPSTTYAVKICKTQESKVAASYC-SPAVPVHFNIQQDCGHFV
ASVPSSMLLAS--DVGKSM-PGDGFHPSHTASEHDCVVVITREVPSQTTADFVRDSV

PF07714 // ENSGT00460000041554_1_Domain_1 (1378, 1621)

MLH
QAKPELYERRVCFLLLQLCNGLEHLKEHGIIHRDLCLENLLLVPCKP-------------
--------------------------------------------------PMSCVKAKDD
KLLPRLIISNFLKAKQKTGT-----GDSKLKKSQARLAPEIVSASQYKKFDEFQTGILIY
ELLHQPNPFEEKVHLREQEYSPEDLPALPSLSIYSR---GLQQLAHLLLEADPIKRVRIT
EAKRMLQCLLWGPRKDLMEQPLSHEETLCQVLQNWVDMKRALLMMKFAERAVDMERSIEL
EDWLCCQYLASAKPTSLLHTLKLLQLL---------

-------------------------TRWALALSLQDLKMSACSDFVEHVWKPGSCKNCFN
PKSSHRLQTPPDVGAC-----GVIP-----NGGRSKPESSALEDESI--NTSVFSKPTIA
VKPTMINSDVSDTWADVNMN---SDLSQVGWGMVSGKHLLL-------------------
-----NPPRD-CLSCCTPSYSMVGLRGLESHVERNVSIHSLVLVGEVGKQEERAKEKSA-
-LP--HRPLCPN---LGDRGVVSSGRNSS--------------PSEGDCG-RLCSGVEGE
GGEYCSI-AESH--------------------RESPAP-RSWRQRDAVELSRLSSRAVKF
SEEEHRAVNVAFCIAKE-----------QSDLLPYTLCAESKKLTRQSDSVALPE--S--
------SSKMAASAPCREKDDLPLPRD-----------------MDGGSRPEGLNAPQQA
LVEPQRAR-LTEPPRGDPIYAESTKRKKAQLKGV-GGCVDAEKL--ASSKEQ--------
-ADGTW-RDGSWLLGAEKEQQDSTAQVAAKITIMAAHTEDDHKTIFLSSPDSAVGVQWPC
VSPASHPDFGTSSPTVEPGETFQAS----GSENAPRFH-----LAAPTKNTVMESPAIPP
KMSKNSQQGSETS-----------------------------------------------
------------------------------------------------------------
------------------SSPCTHVNGIS-----------VEESSRGLAGSPYDRRQKYY
TPTWAKQCRIEEEEE--EEEEQELSTHQWTMGAENGRTGA----------------DLVE
DCPVLESQAGISKSLSFSFDFPKDKSNGVEF-APPPPPPKKQSRHTLKMNPNNAELERAS
NSSAESLSPP-FRS-----VHVSFTAGSSDSLNSDTQAGSDGRHSSEP-----------N
HSPPPAE---SLAFPP-VPFPPASGDDSLSSVS-SRPPPLPQKKTVSRTVS-SPDGFFVG
QGSSGRAA-GTACPRLNVSHSESNVCLHEDSPFLHLASLRGH-PSIFSSSESLEKGSKG-
NGYWGSTTSK-----NTGTCVPSR---NLQS--RSSSQLSMSSQVSSGSS--LQLHNLLS
NIDSKEGVYAKLGALYAESLRRLVAKCEDCFMREQKNEL-HFNENNW-SLFKLACNKPCC
D----SGDAIYYCATCSKDPSTTYAVKICKTQESKVAASYC-SPPVPVH

PF00069 // ENSGT00460000041554_1_Domain_1 (1310, 1626)

FNIQQDCGHFV
ASVPSSMLLAS--NVGKSV-SGDGLRPSRTTSEHDCVVVITREVPSQTTADFVRESVALH
QAKPEMYERRVCFLLLQLCNGLEHLKEHGIIHRDLCLENLLLVPCKP-------------
--------------------------------------------------PMSCAKARDD
RNLPRLIISNFLKAKQKPGS-----GDSKLKKSQARLAPEIVSASQYKKFDEFQTGILIY
ELLHQPNPFEEKVHLKEQEYSPEDLPSLPSLSIYSR---GLQQLAHLLLEADPIKRVRIT
EAKRMLQCLLWGPRKDLTEQPLSHEEALHQVLQNWVDMKRALLMMKFAERAVDTERSVEL
EDWLCCQYLASAEPVSLSHTLKLLQLL---------

------------------------------------------------------------
------------------------------------------------------------
----------------------------VIWRRTPGKHPLPKP-QEDVPIVYLGSFRGVQ
RPPASPTSTD-GHTRCPPAYTMVGLQSLEARGS--PTFHPTGYPAEKAGRDEKPAGSHSD
-LPAAQDSFRQKLATFAG-LPSVGSPGPG------PQP--ESLASEDDSDQRCSPSGDSE
GGEYCSI-LDCCPGSPAGPDAPPAQGSQA-RGRRDCPP-ARWKQAPEE------------
-------E-------GM--------RWGTGPPE-TPPRLGSRRAPLTCEAFTSSDGRSCG
S-R--SSGSSSLFALHLDSDYCSLVKEL----------ALGMSR--PGDSLGTSSRSPGL
LAPPR--------APLELIYAESTKRKKAVLALA-KAQAKAELVSHV----S--GQGLVR
-ISNAWDSQRAAGWVRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXX-----XXXXXXX----XXXXXXXXXX-----XXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXX-----XXXXXXXXXXXXX-X----------XXXXXXXXX-----
------------------------------------------------------------
-------------XXXXXXXXXXXXXXXX--XXXXXXXXXXXX--XX--XXXXXXXXXXX
XGPWSRQCRIER--EVEQDLLSQ----SWAREKENA----PDHSSSSTWHRLRPPDGT--
AEPNGKVGVGMSKSASFAFEFPKDRSGMETF-SPPPPPPK--SRHLLKMNKSSSDLEKVS
QGSTESLSPS-FRG-----AQVSFTAGSTDSLASDSRTCSDGGPSSEP-----------T
HSPTHSG---KKLFTP-VPFPSSSAEDVSPSGP-LQPPPLPQKKLVSRAAS-SPDGFFWT
HGSPKPRT---ASPKLNLSHSETNVCAPEEPPFSYSCSPGNFQHPLFSSSEPLEKAFKG-
NSPWGRASG--L---------AGSPCRGGPS--AASSQLSVSSQASSSST-QLQLHSLLS
SIGSKEGTYAKLGALYAQSLVRLGAKCEDLFLGGQKKEL-HFDENNW-SLFK

PF00069 // ENSGT00460000041554_1_Domain_1 (1253, 1626)

LTCNKPCC
D----SGDAIYYCATCSEDPGSTYAVKICKTPEPKS-AASC-SPSVPVHFNIQQDCGHFV
ASVPSSMLTSP--DA-PKAPL-PALSSHPPAQEQDCVVVITREVPHQTASDFVRDSAASH
QAEPEAYERRVCFLLLQLCNGLEHLKEHGVIHRDLCLENLLLVHCTPPATPCHTPAPPPA
P----------------------------------AAASPPR-----ALPPPVCGGAPGE
KHLPRLIISNFLKAKQKPGS----IPNQQQKKSQARMAPEIVSASQYRKFDEFQTGILIY
ELLHQPNPFEVRAQLREQDYRQEDLPPLPGLSLYSP---GLQRLAHLLLEADPIKRIRIG
EAKRVLQCLLWGPRRDLLEQPGGSEEALRATLHNWIDMKRALMMMKFAEKAVDRRRGLEL
EDWLCCQYLAAAEPSALLQSLKLLQLL---------

-------------------------MHQTLRLKPGSLKMSACSDFVEHIWKPGSCKNCFC
LRSDHQLVAGPPQPRA-----GSLPP-PPR--LPPRPENCRLEDEGV--NSSPYSKPTIA
VKPTMMSSEASDVWTEAGLS---AEVSQVIWRRAPGKLPLPK--QEDAPVVYLGSFRGVQ
KPAGPSTSPDGNSPRCPPAYTMVGLHNLEPRGERNIAFHPVSFPDDKAGHKEKPSFPYQD
-RSSTQGSFRQKLAAFAG-TTSGCHQGPG------PLR--ESLPSEDDGDQRCSPSGDSE
GGEYCSI-LDCCPGSPVAKAASQAAGSRGRHSGRDGSP-TCWEQGKCAGPTEQ-------
-------EKRGLSFPKE--------CCSQGPTA-HPSCLGPKKASFTSEAATSSDGLACG
SGS--GSGASNPFVPHLESDYCSLMKEP-----------TPEKQQDLGCPGVASSRCLGL
TGEPQPPAHPREATQPEPIYAESTKRKKAAPLPS-KPQAKTEHAAAAQGQGQGQGQGQVW
-TGNAWAQKTASGWGQDS--PDPTPQVAATITVMAAHPEEDHRTIYLSSPDSAVGVQWPP
GPGSQNSEVGE------EE--TLA----RQGLSSRESH-----THSAKESKPKERPAIPP
KLSKSSPGGSPVSPSAGGPPVSPLADLSDGSSGS------------SGIGPQPPS-----
------------------------------------------------------------
-------------RGPADPIPPCRTNGVT--LSDPSRCPQPVT------SALDQRRPRFQ
AGTWSRQCRIEEEEEVEQELLSH----SWGRETKNG---PTDHSNSTTWHRLHPTDGS--
SGQNSKVGTGMSKSASFAFEFPKDRSGIETF-SPPPPPPK--SRHLLKMNKSSSDLEKVS
QGSAESLSPS-FRG-----VHVSFTTGSTDSLASDSRTCSDGGPSSEL-----------A
HSPTNSG---KKLFAP-VPFPSGSTEDVSPSGP-RQPPPLPQKKIVSRAAS-SPDGFFWT
QGSPKPQT---ASPKLNLSHSETN--VHDESHFSSSLSPGNRHHAVFSSSDPLEKAFKG-
SGHWVPAAG--LAGNTGGCGSPGLQCKGTPS--ASSSQLSVSSQASTGST-QFQLHGLLS
NISSKEGTYAKLGGLYTQSLARLVAKCEDLFMGGQKKEL-HFNENNW-SLFKLTCNKPCC
D----SGDAIYYCATCSEDPGSTYAVKICKTPEPKT-VSYC-SPSVPVHFNIQQDCGHFV
ASVPSSMLTSP--DA-PKDPV-PTLPAHPPAQEQDCVVVITREVPHQTASDFVRDSAASH
QAEPE

PF00069 // ENSGT00460000041554_1_Domain_1 (1386, 1623)

AYERRVCFLLLQLCNGLEHLKEHGIIHRDLCLENLLLVHCTPQAAPGPTPAT---
-------------------AAP-----PC-SSAALPAGGTLSPA-----AGPASPEGPRE
KQLPRLIISNFLKAKQKPGG----TPNLQQKKSQARLAPEIVSASQYRKFDEFQTGILIY
ELLHQPNPFEVRAQLRERDYRQEDLPPLPALSLYSP---GLQQLAHLLLEADPIKRIRIG
EAKRVLQCLLWGPRRELVQQPGTSEEALCGTLHNWIDMKRALMMMKFAEKAVDRRRGVEL
EDWLCCQYLASAEPGALLQSLKLLQLL---------

-------------------------MHQTLLLKPESLKMSACSDFVEHIWKPGSCKNCFC
LRSDHQLVAGPPQPRA-----GSLPP-PPR--LPPRPENCRLEDEGV--NSSPYSKPTIA
VKPTMMSSEASDVWTEASLS---AEVSQVIWRRAPGGC----------PVVYLGSFRGVQ
KPAGPSASPDGNSPRCPPAYTMVGLHNLEPRGERNIAFHPVSFPDEKAGHKEKPSFPYQD
-RPSTQESFRQKLAAFAG-TTSGCHQGPG------PLR--ESLPSEDDSDQRCSPSGDSE
GGEYCSI-LDCCPGSPVAKAASQAAGSRGRHSGRDGSP-TCWEQGNCAGPTEQ-------
-------EKRGLSFPKE--------CCSQGPTA-HPSCLGPKKASFTSEAATSSDGLSCG
SG----SGASKPFVPHLESDYCSLMKEP-----------APEKQQDLGCPGVASSRCLGL
TGEPQPPAHPREATQPEPIYAESTKRKKAAPVPS-KPQAKTEHAAAAQ------GQGQVW
-TGNAWTQKTASGWGQDS--PDPTPQVAATITVMAAHPEEDHRTIYLSSPDSAVGVQWPR
GPVSQNSEVGE------EE--TLA----RQGLSSRESH-----AHSANESKPKERPAIPP
KLSKSSPGGSPVSSSAGGPPVSPLADLSDGSSGS------------SGIGHQPPS-----
------------------------------------------------------------
-------------RGPADPVPPCRTNGVT--LSDPSRCPQPVT-----SSALDQRRPRFQ
AGTWSRQCRIEEEEEVEQELLSH----SWGRETKNG---PTDHSNSTTWHRLPPTDGS--
SGQNSKVGTGMSKSASFAFEFPKDRSGIETF-SPPPPPPK--SRHLLKMNKSSSDLEKVS
QGSAESLSPS-FRG-----VHVSFTAGSTDSLASDSRTCSDGGPSSEL-----------A
HSPTNSG---KKLFAP-VPFPSGSTEDVSPSGP-LQPLHSP-EKIVSRAAS-SPDGFFWT
QGSPKPQT---ASPKLNLSHSETN--VHDESHFSYSLSPGNRHHAVFSSSDPLEKAFKG-
SGHWVPVAG--LAGNRGGCGSPGLQCKGTPS--ASCSQLSVSSQASTGST-QFQLHGLLS
NISSKEGTYAKLGGLYTQSLARLVAKCEDLFMGGQKKEL-HFNENNW-SLFKLTCNKPCC
D----SGDAIYYCATCSEDPGSTYAVKICKTPEPKT-VSYC-SPSVPVHFNIQQDCGHFV
ASVPSSMLTSP--DA-PKDPV-PALPAHPPAQEQ

PF07714 // ENSGT00460000041554_1_Domain_0 (1355, 1423)

DCVVVITREVPHQTASDFVRDSTASH
QAEPEAYERRVCFLLLQLCNGLEHLKEHGIIHRDLCLENLLLVHCTPGRPAPPPPPPRSL
S------------------PAP-----PL-HAWWPP---------LGPAAGPASPEG---
---------------RKSGG----TPNLQQKEEPGRLAPEIVAASQVPQRSI--------
-EFQTPNPFR----------GAETWPPLPALSLYSPGSPGLQQLAHLLLEADPIKRIRIG
EAKCVLQCLLWGPRRELVQQPGTSEEALCGTLHNWIDMKRALMMMKFAEKAVDRRRGVEL
EDWLCCQYLASAEPRALLQSLKLLQLL---------

MLGGVNLLVKTLIRQLAELRRTVQKTHWALALSLQDLKMSACSDFVEHVWKPGSCKNCFN
PKSSHRLQTSPDVGAC-----GVLP-----NGGRSKPESPALEDEGV--NTSVFSKPTIA
VKPTMINSDVSDTWADVNMN---ADLSQVGWGMVSGKHLLLKSGDSQRICLDGFGASGVR
KPFLQSPPRD-CLSCCTPSYSMVGLRSLESHVERNVSIHSLVLVGEVGKQEERAKEKSA-
-LP--HRPLCPN---VGDRSVVSSGRNPS--------------PSEGDCG-LLSSGIEGE
GGEYCSI-AESH--------------------GESPAP-RSWRQRDAVELPRPSGRAVKF
SEEERRAVNVAFCIAKE-----------RSDLLPYTPCAESKKLTHQSNTTALPE--G--
------SSKMAASAPCREKDDLPLPRD-----------------LDGGPRPEGLNAPQQA
LVEPQRAR-LTEPARGDPIYAESTKRKKAQLKGV-GGCVDAEKL--AGGKEQ--------
-ADGTW-RDGSWLLGAEKEHQDSTAQVAAKITIMAAHTEDDHKTIFLSSPDSAVGVQWPC
ISPASHPDFGTSSPAVEPGEIFQAS----GSENGPRFH-----LAAPTKNVVMESPAIPP
KMSKNSQQGSEGSHVP--PVSSSVTKLGDTISQDGA-------------AAQLLP-----
--------RSCADAST--------------------------------------------
--------------FRTSPSLCTHVNGIS-----------MEESSRGLAGSPYDRRQKYY
TPTWAKQCRIEEEEEEEEEEEQELSTHPWAVGAESGRAGA----------------DLIE
DCPVLESQAGISKSLSFSFDFPKDKSNGMEF-APPPPPPKKQSRHAPKMNPNNAELERAS
NSSAESLSPP-FRS-----IRVSFTAGSSDSLDSDVQTGSDGRHSSEP-----------N
HSPPPAE---SLAFPP-VPFPPASGDDSLSSVS-SRPPPLPQKKTVSRTVS-SPDGFFGG
QGSSGRAA-GTACPRLNVSHSESNVCLREESPFLHPASFRGH-PSIFSSSESLEKGSKG-
NGYWGSATSK-----STGTCVPSR---NLQS--RSSSQLSMSSQVSSGSS--LQLHNLLS
NIDSKEGVYAKLGALYAESLRRLVAKCEDCFMREQKNEL-HFSENNW-SLFKLACNKPCC
D----SGDAIYYCATCSKDPSTTYAVKICKTQESKVAASYC-SPPVPVHFNIQQDCGHFV
ASVPSSMLLAS--DVGKSV-SGDGLRPSRTASEHDCVVVITREVPSQTTADFVRDSVTLH

PF00069 // ENSGT00460000041554_1_Domain_1 (1381, 1624)

QAKPEMYERRVCFLLLQLCNGLEHLKEHGIIHRDLCLENLLLVPCKP-------------
--------------------------------------------------LMSCAKAKDD
RNLPRLIISNFLKAKQKPGS-----GDSKLKKSQARLAPEIVSASQYKKFDEFQTGILIY
ELLHQPNPFEEKVHLKEQEYSPEDLPSLPSLSIYSR---GLQQLAHLLLEADPIKRVRIT
EAKRMLQCLLWGPRKDLTEQPLSHEEALHQVLQNWVDMKRALLMMKFAERAVDTERGVEL
EDWLCCQYLASAEPVSLSHTLKLLQLL---------

-------------------------MHQTVRLSAESPKMSACSDFVEHIWKPGSCKNCFC
LRSDHQLAPGQPQPRA-----GHLPP-PPR--LPPRPDTCRLEDEAV--NGSPYSKPTIA
VKPTMMNADASDVWTEANLS---ADVSQVIWRRAPGKLPLPQ--QDDVPIVYLGSFRGVQ
KAAGPSASTD-GHTRCPPAYAMVGLHSLEARGERPTAFHPVSFSPEKAGREEKPMFPYQE
-LTSAQESFRQKVAAFAG-MTSGCHKGPGPCPSPQPLR--ESLPLEGDSDQRCSPSGDSE
GGEYCSI-LDCCPGSPIATDTSQAESSRCRPGRGDRSP-PCWAQGVCAGPPEE-------
-------EKRALGFRRE--------GSA-----ENPPRLAPKKLSLTSEAASSSDGLSCG
S-A--SSGASSPFAPHLDSDYCSLTKEP-----------VPGKPQDSGCHLATSNRGLGL
TGEPQPPAHLQEAVQPEPIYAESTKRKKVAPAPS-KPQAAVEQAAAARGQGQ--GQGQVR
-TANAWAQKSASGWGRDREGPDRAPPVAATITVMAAHPEEDHRTIYLSSPDSAVGVQWPR
GPMSQDSE---A-----GEEEASA----GQGTSSREGA-----RPDASENTPKGKPAIPP
KLSKSSPGGSPVSPST-----SPFSDLSEGSSTG-------------GPGPQASS-----
------------------------------------------------------------
-------------RAPTDSAASCRANSVTA-TSDSARCPPPAAAA----STLDQRRPRYQ
TGAWSRQCRIEEEEEVEHELLSK----SWGREMENG---TVEPSSSSTWHRLRPTDSS--
SAQSSKVGTGMSKSASFAFEFPKDRSGIEVF-SPPPPPPK--SRHLLKMNKSSSDLEKVS
QGSAESLSSP-CRG-----VHVSFNTGSTDSLASDSRTCSDGGPSSEP-----------A
HSPTSSG---KKLFAP-VPFPSGSTEDVSPSGP-LQPPPLPQKKLVSRAAS-SPDGFFWT
QGSPKPRT---ASPKLNLSHSETNVCAHEDPHFSYSSSPGSRHHPIFSSSEPLEKTFRS-
NGHWVPAPG--LAGSKSSCGSPSLRCRGVPS--ATSSQLSVSSQASASST-QLHLHSLLS
SISSKEGTYAKLGGLYAQSLVRLAAKCEDLFMGGQKKEL-HFNENNW-SLFKLTCNKPCC
D----SGDAIYYCATCSEDPGSTYAVKICKTPEPKT-ASYC-SPSVPVHFNIQQDCGHFV
ASVPSSMLTSP--DA-LKDPL-PAPPSHPPAQEQDC

PF07714 // ENSGT00460000041554_1_Domain_0 (1357, 1423)

VVVITPEVPHQTASDFVRNSATSH
QSEPEAYERRVCFLLLQLCNGLEHLKEHGIIHRDLCLENLLLVHCSPQASPRPARAXXXX
XXXXXXXXXXXXXXXXXXXPLPPLARLPLPPSVALPASRWPPP-ARTGPVRSACPGSSSA
TS----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------

-------------------------MHQAVPLNPGGPKMSACSEFVEHIWKPASCKNCFC
LRSEHPPAAGRP---------GSLPP-PPR--LPPRPEACRPEDEGV--SGSPYSKPTIA
VKPTMMSAEGPDVWLEAAPG---ADVPQVIWRAAPSK-------QEEAPRAYLSSFRAAP
KPGAA--PAD-GGPRCPPAYALVGLHSLELRAERSAAFHPVGFPDQNGGREAGATFSYQE
-LTATQESFRQKLAAFAG-MASGCAKGPGPCFSAQPLR--GSVPSEDDSDQRHSPSGDSD
GGEYCSI-LDCCPGSPIADDPSATEGSRARHGGGDRSP-SHWDPGTRAGPPAG-------
-------EK-HLSLPRE--------RCSQDLPE-GPGRLAPRQRSPPLEAASSCDGLSCD
SS-------SSGSAPHLDSDYCSLVKEP-----------TPGKQPGLDRHGGMSSRCPGL
SGEPQLPAHPRGA-TLEPIYAESTKRRKAGPPPS-RPQAEAEQAR---------------
-TGSARAQRAAPGWARDGEGPEAGAQVAATITVMAAHPEEDHRTIYLSSPDSAVGVQWPR
RPGSQDCE---A-----GDSGASA----GQGPGCRDGR-----AHEARESVPTARPAIPP
KLSRGSSGGSPVPPSA-----SLLADLSDRSASGALRPQPVPRGPANPVGPHPVPRGPAD
PVGSHPVPRGPADPVGLHSVPKGPADPMGSHPVPRGPANSVGPQPVPRGPANPMGSHPVP
RGPADPMGSHPVPRGPADPTSSCRVDA--------GRASP------PIASTMDQRWPRLQ
AAAWSHQCRIVEEEELGQALPGR----GRAGGVDAG---PAGPSSSSTWHRLRPPEAA--
CGQSSKAGAGMSKSASFAFEFPKDRSGLEAF-SPPPPPPK--SRHLLKMNKSSSDLEKAS
QGSAESLSPS-FRG-----VHVSFTAGSSDSLASDSRTCSDGGPPYEP-----------A
PSPTNSG---KQLFPP-VPFPSGSTEDVSPRGT-LQPPPLPQKKVVSRTAS-SPDG-FWT
QGSPKPRA---ASPKLNLSHSETNICVHEDPRF-YPSSPGSRPQHAS----PSEKPSRG-
SGPWAPAPP------------------------AASSPLSMASQAAAAGS-QLQLHSLLG
SVSSREATCAKLGELYAQSLLRLAAKCEDLFMGGQKTEL-HFSENNW-SLFKLTCNKPCC
D----SGDAIYYCATCSEDPGSTYAVKICKTPEPKA-ASCC-SPSVPVHFNIQQDCGHFV
ASVPSSMLGPP--DA-PRD----APPAPAPAQEQDCVVVITREVPHQTAADFVRGSAASH
QAEP

PF07714 // ENSGT00460000041554_1_Domain_1 (1385, 1568)

DAYERRVCLLLLQLCHGLEHLKEHRVIHRDLCLENLLLVHCAPRPTPGP-------
------------------------------------------------PGPAACRGAPAE
KRLPRLIISNFLRAKQKPGG----AASPQQQKSQARLAPEIVSATQYRKFDEFQTGILIY
ELLHQPNPFEVRAQLRERDYRREDLPPLPALSLYSP---GLQRLAHLLLEADPARRIGIG
EAKRALQCLLWGPRRELAEQLGTPEEALRGALQNWIDVKRALMMVKFAEKAVERRREVEL
EDWLCCQYLVPAQPAALLQTLKLLQLL---------

-------------------------MHQTLCLNPESLKMSACSDFVEHIWKPGSCKNCFC
LRSDHQLVAGPPQPRA-----GSLPP-PPR--LPPRPENCRLEDEGV--NSSPYSKPTIA
VKPTMMSSEASDVWTEANLS---AEVSQVIWRRAPGKLPLPK--QEDAPVVYLGSFRGVQ
KPAGPSTSPDGNS-RCPPAYTMVGLHNLEPRGERNIAFHPVSFPEEKAVHKEKPSFPYQD
-RPSTQESFRQKLAAFAG-TTSGCHQGPG------PLR--ESLPSEDDSDQRCSPSGDSE
GGEYCSI-LDCCPGSPVAKAASQTAGSRGRHGGRDCSP-TCWEQGKCSGPAEQ-------
-------EKRGPSFPKE--------CCSQGPTA-HPSCLGPKKLSLTSEAAISSDGLSCG
SGSGSGSGASSPFVPHLESDYCSLMKEP-----------APEKQQDPGCPGVTPSRCLGL
TGEPQPPAHPREATQPEPIYAESTKRKKAAPVPS-KSQAKIEHAAAAQG------QGQVC
-TGNAWAQKAASGWGRDS--PDPTPQVSATITVMAAHPEEDHRTIYLSSPDSAVGVQWPR
GPVSQNSEVGE------EE--TSA----GQGLSSRESH-----AHSASESKPKERPAIPP
KLSKSSPVGSPVSPSAGGPPVSPLADLSDGSSGG------------SSIGPQPPS-----
------------------------------------------------------------
-------------QGPADPAPSCRTNGVA--ISDPSRCPQPAA-----SSASEQRRPRFQ
AGTWSRQCRIEEEEEVEQELLSH----SWGRETKNG---PTDHSNSTTWHRLHPTDGS--
SGQNSKVGTGMSKSASFAFEFPKDRSGIETF-SPPPPPPK--SRHLLKMNKSSSDLEKVS
QGSAESLSPS-FRG-----VHVSFTTGSTDSLASDSRTCSDGGPSSEL-----------A
HSPTNSG---KKLFAP-VPFPSGSTEDVSPSGP-QQPPPLPQKKIVSRAAS-SPDGFFWT
QGSPKPGT---ASPKLNLSHSETN--VHDESHFSYSLSPGNRHHPVFSSSDPLEKAFKG-
SGHWLPAAG--LAGNRGGCGSPGLQCKGAPS--ASSSQLSVSSQASTGST-QLQLHGLLS
NISSKEGTYAKLGGLYTQSLARLVAKCEDLFMGGQKKEL-HFNENNW-SLFKLTCNKPCC
D----SGDAIYYCATCSEDPGSTYAVKICKAPEPKT-VSYC-SPSVPVHFNIQQDCGHFV
ASVPSSMLSSP--DA-PKDPV-PALPTHPPAQEQDCVVVITREVPHQTASDFVRDSAASH
QAEPE

PF00069 // ENSGT00460000041554_1_Domain_1 (1386, 1623)

AYERRVCFLLLQLCNGLEHLKEHGIIHRDLCLENLLLVHCTLQAGPGPAPAPA--
--PAPAPAA----------AAP-----PC-SSAAPPAGGTLSPA-----AGPASPEGPRE
KQLPRLIISNFLKAKQKPGG----TPNLQQKKSQARLAPEIVSASQYRKFDEFQTGILIY
ELLHQPNPFEVRAQLRERDYRQEDLPPLPALSLYSP---GLQQLAHLLLEADPIKRIRIG
EAKRVLQCLLWGPRRELVQQPGTSEEALCGTLHNWIDMKRALMMMKFAEKAVDRRRGVEL
EDWLCCQYLASAEPGALLQSLKLLQLL---------

-------------------------MHQTLRLKPESLKMSACSDFVEHIWKPGSCKNCFC
LRSDHQLVAGPPQPRA-----GSLPP-PPR--LPPRPENCRLEDEGV--NSSPYSKPTIA
VKPTMMSSEASDVWTEASLS---AEVSQVIWRRAPGKLPLPK--QEDAPVVYLGSFRGVQ
KPAGPSTSPEGNSPRCPPAYTMVGLHNLEPRAERNIAFHPVSFPDDKAGHKEKPSFPYQD
-RPSTQESFRQKLAAFAG-TTSGCHQGPG------PLR--ESLPSED--DQRCSPSGDSE
GGEYCSI-LDCCPGSPVAKAASQAAGSRGKHSGRDGSP-TCWEQGKCAGPTEQ-------
-------EKRGPSFPKE--------CCSQGPTA-HPSCLGPKKASFTSEAATSSDGLACG
SGS--GSGASNPFVPHLESDYCSLMKEP-----------APEKQQDLGCPGVASSRCLGL
TGEPQPPAHPREATQPEPIYAESTKRKKAAPVPS-KSQAKTEHAAAAQGQGQGQGQGQVW
-TGNAWAQKTASGWGQDS--PDPAPQVAATITVMAAHPEEDHRTIYLSSPDSAVGVQWPP
GPGSQNSEVGE------EE--TWA----RQGLSSRESH-----AHSAKESKPKERPAIPP
KLSKSSPGGSPVSPSAGGPPVSPLAHLSDGSSGS------------SGIGPQPPS-----
------------------------------------------------------------
-------------RGPADPVPPCRTNGVT--LSDPSRCPQPVT------SALDQRRPRFQ
AGTWSRQCRIEEEEEVEQELLSH----SWGRETKNG---PTDHSNSTTWHRLHPTDGS--
SGQNSKVGTGMSKSASFAFEFPKDRSGIETF-SPPPPPPK--SRHLLKMNKSSSDLEKVS
QGSAESLSPS-FRG-----VHVSFTTGSTDSLASDSRTCSDGGPSSEL-----------A
HSPTNSG---KKLFAP-VPFPSGSTEDVSPSGP-RQPPPLPQKKIVSRAAS-SPDGFFWT
QGSPKPQT---ASPKLNLSHSETN--VHDESHFSSSLSPGNRHHAVFSSSDPLEKAFKG-
SGHWVPAAG--LAGNRGGCGSPGLQCKGTPS--ASSSQLSVSSQASTGST-QFQLHGLLS
NISSKEGTYAKLGGLYTQSLARLVAKCEDLFMGGQKKEL-HFNENNW-SLFKLTCNKPCC
D----SGDAIYYCATCSEDPGSTYAVKICKTPEPKT-VSYC-SPSVPVHFNIQQDCGHFV
ASVPSSMLTSP--DA-PKDPV-PTLPAHPPAQEQDCVVVITREVPHQTASDFVRDSAASH
QAEPE

PF00069 // ENSGT00460000041554_1_Domain_1 (1386, 1623)

AYERRVCFLLLQLCNGLEHLKEHGIIHRDLCLENLLLVYCTPQAAPGPTPAT---
-------------------AAP-----PC-SSAALPAGGTLSPA-----AGPASPEGPRE
KQLPRLIISNFLKAKQKPGG----TPNLQQKKSQARLAPEIVSASQYRKFDEFQTGILIY
ELLHQPNPFEVRAQLRERDYRQEDLPPLPALSLYSP---GLQQLAHLLLEADPIKRIRIG
EAKRVLQCLLWGPRRELVQQPGTSEEALCGTLHNWIDMKRALMMMKFAEKAVDRRRGVEL
EDWLCCQYLASAEPGALLQSLKLLQLL---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------MTSGCHKGSGSYPSAQPLR--ESLPSEDDSDQRCSPSGDSE
GGEYCSI-LECCPGSPGVEDTSQAEGSRHRHGGRDCLP-ACWEQGVCARPTPE-------
-------EKRALSFPRE--------CCSQGPAE-NPPRLGPKKQSLTSEAASSSDGLSCG
S-V--SSRASSPLSPHVESDYCSLMKEP-----------GSGKQQDPGCHRVASSRCLGL
TVEPQPPAPSREAAQPEPIYAESTKRKKAVSMPS-RPQAKAEQAAAAP---G--P---GA
-DSKYLGSENSPGRGQDKEGSDMAPQVAATITVMAAHPEEDHRTIYLSSPDSSVGVQWPR
GPPSQTPE--A------GEESPSA----GQGLSSRESH-----HLGASENTPKGRPAIPP
KLSRSSPGGSPVSPSA-----SPLSDLSEG-NS--G-----------VPGPQRPS-----
------------------------------------------------------------
-------------RGPADPTSSCQANSVP--TSDSVRGPPSGT--------TTSRRPRYQ
TGAWSRQCRIEEEEEVEQDLLSQ----SWGREVENG---PTDPSNSSTLHHLRPTDGT--
SGQNNKAGTGMSKSASFAFEFPKDRSGIETF-SPPPPPPK--SRHLLKMNKSSSDLEKVS
HGSAESLSPS-FRG-----IHVSFTTGSTDSLASDSRTCSDGGTSSEP-----------P
HSPISSG---KKLFAP-VPFPSGSAEDMAPSGP-LQPPPLPQKKLVSRAAS-SPDGFFWT
QGSPKPRT---ASPRLNLSHSETNVCVHEESHFGDSSGPGHHHQHIFSASEPLEKTFKG-
SGHWGPARG--LAGS------GSLQGKGVTS--ASASQLSVSGQASAGST-QLQLHSLLS
SIGSREGTYAKLGGLYAQSLVRLVAKCEDLFMGGQKKEL-HFSENNW-SLFKLTCNKPCC
D----SGDAIYYCATCSEDPGSTYAVKICKTPEPKA-ASYC-SPSVPVHFNIQQDCGHFV
ASVPSSMLTSP--DA-PKVPL-PALPSHPPSQEQDCVVVITREVPHQTASDFVRDSATSH
QS

PF00069 // ENSGT00460000041554_1_Domain_1 (1383, 1623)

EPEVYERRVCFLLLQLCNGLEHLKEHGIIHRDLCLENLLLVAPPT-------------
----------------TISPAPAATPSSC-PSAALPA------------TAPACQGGPSE
KHLPRLIISNFLKAKQKPGS----TTNLQQKKSQARLAPEIVSASQYRKFDEFQTGILIY
ELLHQPNPFEVRAQLREQDYRQEDLPPLPALSLYSP---GLQRLAHLLLEADPIKRIRIN
EAKRVLQCLLWGPRRELVEQPGTSEEVLCTTLNNWIDMKRALMMMKFAEKAVDRRRGVEL
EDWLCCQYLASAEPVALLQSLKLLQLL---------

-------------------------MHQALRLNPESPKMSACSDFVEHIWKPGSCKNCFC
LRSDHQLAAGHPQPRA-----GNPPP-PPR--LPPRPENCRPDDEGV--NSSPYSKPTIA
VKPTMMSSDASDVWTEANLS--TADVSQVIWRRAPGKLPLPK--QDDVPIVYLGSFRGVQ
KAPGPAASSE-GHSRGPPAYAMLGLHSLEARGERSTAFHPVSFSSDKVGREDKPMFSYQE
-LTSTQESFRQKVAAFAG-TTSGCHKGPGPCPAAQPLR--ESLPSLDDSDQRCSPSGDSE
GGEYCSI-LDCCPASPVAADTPQAEGSGCGPGRGDCPP-LCWEQGLCAGPPDE-------
-------ETRGLSFPRE--------CCSQGPAE-KPPRLGPKKLSLTSEAASSSDGLSCG
S-A--SSGASSPFAPHLDSDYCSLMKEP-----------VPGKQQDSGCHAVTSSRCLGL
PGEPQPAAHPSEAAQPEPIYAESTKRKKAVPAPS-KPQATAEQAAAARGQGQ--GQGQVR
-TATTWAQKAASGWGRDREGPDMAPQVAATITVMAAHPEEDHRTIYLSSPDSAVGVQWPR
RPVSQDSE--A------GEEEVSA----GQALSSRESH-----RPDASENSLKGKPAIPP
KLSKSSPGGSPVSPSA-----SPLSDLSEG-SSS-G-----------GTGPQASS-----
------------------------------------------------------------
-------------RGPTDSASSCRANGIA--ASDSVRCHLPAA--TS--SALDQRRPRYQ
TGAWSRQCRIEEEEEVEQELLSQ----SWGRELENG---TTDPSTSSTWHRLRPTDGS--
SGQSSKVGTGMSKSASFAFEFPKDRSGIEVF-SPPPPPPK--SRHLLKMNKSSSDLEKVS
QGSAESLSPP-CRG-----VHVNFTTGSTDSLASDSRTCSDGGPSSEP-----------A
HSPTNSG---KKLFAP-VPFPSGFTEDVSPGGP-LQPPPLPQKKLVSRAAS-SPDGFFWT
QGSPKPRT---ASPKLNLSHSESNVCAHEESHFSYSSSPGSRHHHIFSSSEPLEKTFKG-
SGHWVPAPG--LVGSKSGCGSPGLQCKGVPS--ASASQLSVSSQASTGST-QLHLHSLLS
SISSKEGTYTKLGGLYAQSLVRLSAKCEDLFMGGQKKEL-RFNENNW-SLFKLTCNKPCC
D----SGDAIYYCATCSEDPGSTYAVKICKTPEPRA-ASYC-SPSVPVHFNIQQDCGHFV
ASVPSSMLTSP--DA-PKDPL-PAPPSQPPAQEQDCVV

PF00069 // ENSGT00460000041554_1_Domain_0 (1359, 1423)

VITPEVPHQTASDFVRDSAASH
QSEPEVYERRVCFLLLQLCNGLEHLKEHGIIHRDLCLENLLLVHCFPQAPPGPSSATPAP
PVSSATPSAP----ATATSPSPAAAPSPC-PPATLPAGVPPS-----SSAAPACQAAPGE
KYLPRLIISNFLKAKQKPGG----TANLQQKKSQARLAPEIVSASQYRKFDEFQTGILIY
ELLHQPNPFEVRAQLREQDYRQEDLPALPALSLYSP---GLQQLAHLLLEADPIKRIRIG
EAKRVLQCLLWGPRRELLEQPGSSEEVLCGTLHNWIDMKRALMMMKFAERAVDRRRGVEL
EDWLCCQYLAAAEPGALLQSLKLLQLL---------

--------------------------------------MSACSDFVEHIWKPGSCKNCFC
LRSDHQLTAGHPKARA-----NSLPA-GSR--LPARPENCRLEDEGV--NGVAYTKPTIA
VKPTMMSSEAADVWTEASLS---AEVPKVNWRRAPGKLPLQK--QDDGPIVYLGSFRGMQ
KPPGSLACAD-GSSCCPPAYTMVGLHNLEARVERNAAFQPVSFQEEKPAREE--------
-LPSAQESFRQKLAAFAG-MTSSCPKGPRPCPSPQPLR--ESLPSEDDSDQRCSPSGDSE
GGEYCSI-LDCCPESKDAAHSTEG--S--GRRGGDCSP-MCWEKGTCTRPTEE-------
-------EKRALNFPRE--------CCVQGSTA-NPSCLGPKKPSLHSEAASSSDGLSCG
S-S--RSGASSPFAPHLDNDYCSLVKEP-----------ALGKQQDSSCHAITSGKCGGQ
AGEPQPPALPREAVPPEPIYAESTKRKKAVPVPS-RSEIKAEPGAAGH------SQGPVW
-TGDTWAQKAPSGWSQDREGTNVAPQVATTITVIAAHPEEDHRTIYLSSPDSAVGVQWPR
GPVNQDTQ---A-----GEEESSA----VKGLSSRESH-----PHNATENMPKEKPAIPP
KLSKSSPGGSPASPAA-----SPLADHSDGNMGG------------SSVGPQLLS-----
------------------------------------------------------------
-------------RVPTNRTSSCQTNGVA--AGDPAKCPPPATSS----SALDQRRPRYQ
TGAWSRQCRIEEEKEVGQELLSQ----SWGREVENG---TADHSNSSTWHRLHPTDG-SS
SGQSGKAGTGMSKSASFAFEFPKDRGRMEAF-SPPPPPPK--SRHLLKMNKSSSDLEKVS
QSSAESLSPS-FRG-----AHVSFTTGSTDSLASDSRTCSDGGPSYEP-----------A
HSPTISG---KKLFAP-VPFPSGSTEDVSPS-GPALPPPLPQKKIVSRAAS-SPDGFFWT
QGSPKPRT---ASPKLNLSHSETNVCVHDEPPFSYSLNSGDHSHPAFSSSEPLEKAFKG-
SAPWGPALG--LVGSKGGCGSPSLQCRAATS--TSSSQLSVSSQTSSSST-QLQLHSLLS
SISSKEGTYAKLGGLYTQSLARLVTKCEDLFMGGQKKEL-RFNENNW-SLFKLTCNKPCC
D----SGDAIYYCATCSEDPGSTYAVKICKTPEPKS-ASYC-SPSVPVHFNIQQDCGHFV
ASVPSSMLASP--DTSSKDPA-PAAPSHSPAQEQDCVVVITREVPHQTASDFVRDSTASH
RA

PF00069 // ENSGT00460000041554_1_Domain_1 (1383, 1623)

EPEVYERRVCFLLLQLCNGLEHLKEHGIIHRDLCLENLLLAHCNPQGSPGPSATPTVP
TTT---TT----------------------------TTTSRCP-SATSTATAPCPGGPGE
KHLPRLIISNFLKAKQKPGG----TTNLQQKKSQARLAPEIVSASQYRKFDEFQTGILIY
ELLHQPNPFEVRAQLRERDYRREDLPPLPTLSLYSP---GLQQLAHLLLEADPIKRIRIG
EAKRVLQCLLWGPRRELVEQPCTSEEVLCSTLHNWIDMKRALMMMKFAEKAVDRRRGVEL
EDWLCCQYLASAEPGALLQSLKLLQLL---------

-------------------------IHQALRLNPESLKMSACSDFVEHIWKPGSCKNCFC
LRGDHQLSPTCPQPRA-----GGLP--PPR--LPPRPEHCRLEDEGV--NSSPYSKPTIA
VKPTMLSSDASDVCTEANMS---PNASQDIWRWAPSKLPFPK--QEDAPMVCLGSFRGVQ
KPAVPAAPAD-GHPRCSPVYAMVSLHSPGARGERTTAFHPLSFPEEKAGREGKPTFPHQE
-PTSAQESRHQKLSGLGSRTTPGCAKDPGTHPSPQPPR--ESLPSEDDSDQRCSPSGDSE
GGEYCSI-LDCCPRSPAAT--SQGEGPRHRPGGGDRSP-TCWEQGLCGGPAED-------
-------VKQVLGFPRE--------CCGQGPAQ-TPPHPGPRKLSLPSEAASSSDGLSCG
S-A--SSGASSPFAPHLESDYCSLVKEP-----------VPGKQQDSGCHAVASNRCLGP
TGEPQPPTHPREAVQPEPIYAESTKRKKAVPVPS-RPQGKAEQPAAGP--------GQGR
-MVSTWTQKTASGGSRDREGPDAGPKVPATITIMAASPKEDHRTIYLSSPDSAVGVQWLR
PSVSQDSG---A-----GDQETSA----GQGKGSREGH-----HHAASQNVPKGRPAIPP
KLSKGSPGGSPVSPSP-----SPLSDLSEGSSG-------------GSTGPQPSS-----
------------------------------------------------------------
-------------RCPADPASSCRANGVA--NHDSAKCPPPATTA----SAADQRRPRYQ
TGAWSRQCRIEEEEEVEQNLLSQ----SWGGETMAKG--TADPSSSSTWHHLCPTDRA--
SGQNDKAGTGMSKSASFAFEFPKDRHGIEAF-SPPPPPPK--SRHLLKMNKSSSDLEKVS
QGSAESLSPS-FRS-----VHVSFTTGSTDSLASDSRTGSDGGPSSEP-----------P
HSPTNSG---KKLFAP-VPFPSGSTEDVSRSSP-LQPPPLPQKKLVSRAAS-SPDGFFWT
QGSPKPRA---ASPKLNLSHSEINVRAHEESHFG----HGNRHHHAFS-SEPLEKTFKG-
NGPA-----PRLAGGRSGSGSPSLQCKGMPS--ASSSQLSVASQASTSSN-QPQLHSLLS
SISSKEGTHAKLVGLYAQSLIRLGAKCEDLFMGRQKKEL-HFNENNW-SLFK

PF00069 // ENSGT00460000041554_1_Domain_1 (1253, 1626)

LTCNKPCC
D----SGDAIYYCATCSEDPGSTYAVKICKTPEPKV-ASYC-SPAVPVHFNIQQDCGHFV
ASVPSSMLAAP--DA-PKDPA-PAPPAPPPAQEQDCVVVITREVPHQTASDFVRDSVGSH
RSEPEAYERRVCFLLLQLCNGLEHLKEHRVIHRDLCLENLLLVHCAPQASPGPPASSA--
-----TASAP----PSTTCTAPAAGPAPG-PSTTLPASITPS-----PPTAPTCEGVPSE
KHLPRLIISNFLKAKQKPGG----TANLQQKKSQARLAPEIVSASQYSKFDEFQTGILIY
ELLHQPNPFEVRAQLWEQDYRREDLPPLPTLSLYSP---GLQQLAHLLLEADPIKRIRIG
EAKRVLQCLLWGPRRELVEQRGTSEEALSSALHNWIDMKRALMMLKFAEKAVDRQRGVEL
EDWLCCQYLASAEPSALLQSLKLLQLL---------

--------------------------------------MSACSDFVEHIWKPGSCKNCFC
LLSDHQPTAGHHKARA-----NSLPA-GTR--LPARPENCRLDDEGV--NGLAYSKPTIA
VKPTMMTSETSDLWTEASLS---AEVPKVNWRRTPGKLLLPK--QEDEPIVYLGSFRGLQ
KPASPLACTD-GNSRCPPAYTMVGLHNLEARVDRNTAFQPVSFQEEKAGREE--------
-LPSAHESFRQKLAAFAG-MTSSCPKGPRPCTSPQPLR--ESLPLEDDSDQRCSPSGDSE
GGEYCSI-LDCCPESKDAVHSTEG--S--GRRGGDCSP-TCREQGPRTRPTEE-------
-------EKQGLSFPRE--------CCGQGSTA-NPPRLGPKKPSLNSEAASSSDGLSCG
S-S--RSGASSPFAPHLENDYCSLMKEP-----------ASGKQQDPSCHFLTSGKCVGQ
AAELQPASLPRDPVQPEPIYAESAKRKKAAPGPP-RPEPKKEQVPAGH------SQGQVW
-TGDTWIQKTPPNWSQDREGAKPASQVAATITVIAAHPEEDHRTIYLSSPDSAVGVQWPR
GPSNQDLQ---A-----SEEEPLV----VQGLTSRESH-----PHNVTENTSKEKPAIPP
KLSKSSPGGSPVSPAA-----PPLTDHSDG----------------SSVGPQLLS-----
------------------------------------------------------------
-------------RVPANLTSSCHTNGVAT-AGDSAKCPPPATSY----SALDQRRPRYQ
TGAWSRQCRIEEEEEVGQEL-SQ----SWGRELENG---TADHSNSSTWHRLHPI-D-GT
SGQNSKTNSGMSKSASFAFEFPKDRGRLEAF-SPPPPPPK--SRHLLKMNKSSSDLEKVS
QSSAESLSPS-FRG-----AHVSFTTGSTDSLASDSRPCSDGGPSYEP-----------T
HSPTISG---KKLFAP-IPFPSGSTEDVSPGGGPAQPPPLPQKKIVSRAAS-SPDGFFWT
QGSPKPRT---ASPKLNLSHSETNVCAHDEPPFNCSLNSGNRSHHVFSSSEPLEKAFKG-
NAPWAPALG--LANSKGGCGSPSLQCRAATS--TSSSQLSVSSQASSSST-QLQLHSLLS
SISSKEGTYAKLGGLYTQSLARLVTKCEDLFMGGQKKEL-RFNENYW-SLFKLTCNKPCC
D----SGDAIYYCATCSEDPGSIYAVKICKTPEPKS-ASYC-SPSVPVHFNIQQDCGHFV
ASVPSSMLAS--PDTSSKDAV-PAASPQPPAQEQDCVVVITREVPHQTASDFVRDSMASH
RA

PF00069 // ENSGT00460000041554_1_Domain_1 (1383, 1623)

EPEVYERRVCFLLLQLCNGLEHLKEHGIIHRDLCLENLLLAHCNPQSSPGPSATPTVP
T------------------------------------TTSRCP-SAAPAATTACQGGPGE
KHLPRLIISNFLKAKQKPGG----TTNLQQKKSQARLAPEIVSASQYRKFDEFQTGILIY
ELLHQPNPFEVRAQLRERDYRREDLPPLPTLSLYSP---GLQQLAHLLLEADPIKRIRIG
EAKRVLQCLLWGPRRELVEQPCTSEEVLCNTLHNWIDMKRALMMMKFAEKAVDRRRGVEL
EDWLCCQYLASAEPGALLQSLKLLQLL---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------SPSVPVHFNIQQDCGHFV
ASVPSSMLTSP--DA-PKAPL-PAPPSHPPAQEQDCV

PF00069 // ENSGT00460000041554_1_Domain_1 (1358, 1623)

VVITREVPHQTASDFVRDSATSH
QSEPEVYERRVCFLLLQLCNGLEHLKEHGIIHRDLCLENLLLVHS---------------
--------------------------------------------------ARACQGVPSE
KHLPRLIISNFLKAKQKPGG----TTNLQQKKSQARLAPEIVSASQYRKFDEFQTGILIY
ELLHQPNPFEVRAQLREQDYRQEDLPPLPTLSLYSP---GLQQLAHLLLEADPIKRIRIG
EAKRVLQCLLWGPRRELVEQPGTSEEVLCGTLHNWIDMKRALMMMKFAEKAVDRRRGVEL
EDWLCCQYLAAAEPGALLQSLRLLQLLASVSLVSKI

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------MSKSASFAFEFPKDRSGIEAF-SPPPPPPK--SRHLLKMNKSSSDLEKVS
QGSAES-----LRG-----VHVSFTTGSTDSLASDSRTCSDGGPSSEP-----------A
HSPTNSR---KKLFAP-VPFPSGSTEDVSPGDP-LQPPPLPQKKLVSRAAS-SPDGFFWP
QGSPKPRT---ASPKLNLSHSETNVCAHEDSHFSYASGPGGRHQHVFSAPEPLEKTSKG-
SGHRGPTPG--LG------GSKGLQGKGVSS--ASSSQLSVSSQASAGST-QLQLHSLLN
SISSKEGTYAKLGGLYAQSLVRLVARCEDLFMGGQKKEL-HFSENNW-SLFKLTCNKPCC
D----SGDAIYYCATCSEDPGSTYAVKICKTPEPKA-ASYC-SPSVPVHFNIQQDCGHFV
ASVPSSMLTSP--DA-HKDPL-SALPSYPPAQEQDCVV

PF07714 // ENSGT00460000041554_1_Domain_0 (1359, 1423)

VITREVPHQTASDFVRDLATSH
QSEPEVYERRVCFLLLQLCNGLEHLKEHGIIHRDLCLENLLLVHCAPQASPEPSPAASIP
PTTTSPXSIP----PPTTSPAPTATPSSG-PSATVPSSVTPT-----PPAAPALQGGSSE
KHLPRLIISNFLKAKQKPGG----TTNLQQKKSQARLASLISCASQYRKFDEFQTGILIY
ELLHQPNPFEVRAQLREQDYRQEDLPPLPA------------------------------
--------------RERVEPPGTSEEALCATLHNWIDMKRALMMMKFAEKAVDRRRGVE-
EDWLCCQYLASAEPAALLQSLKLLQLL---------

-------------------------MHQTVRLSPASPKMSACSDFVEHIWKPGSCKNCFC
LRSDHQLAPGHPQPRA-----GSLPP-PPR--LPPRAETCRQEDDAV--NSSPYSKPTIA
VKPTMMSSDASDVWTEANLS---AEVSQVIWRRAPGKLPLPK--QDDVPIVYLGSFRGVQ
KPAGPSVSAD-GHSRCPPAYAMVGLHSLEARGERSTAFHPVSFPNEKGGREDKPVFPYQE
-LTSTQESFRQKVAAFAG-MTSGCHKGAGPCPSPQPLR--ESLASEDDSDQRCSPSGDSE
GGEYCSI-LDCCPGSPTATATSQAASSRCRPGGGDCPA-VCWGQAVCAGSTEE-------
-------QKHVVSFPRE--------CCSQGPAE-NPPRLGPKKLSLPSEAAGSSDGLSCG
S-P--SSGASSPFAPHLESDYCSLMKEP-----------VPGKQQDAG-----SNRCLGL
TGEPQPPAHPREAVQPEPIYAESTKRKKAVPAPS-KPQATAEHAAAAA---R--GQGQVR
-TANAWAPKAPSGWGRDREGPDKVPQVAATITVMAAHPEEDRRTIYLSSPDSAVGVQWPR
GPLSQDSE--A------GEEETSA----GQGLSSRDSH-----RPDASENTPKGKPAIPP
KLSKSSPGGSPVSPSA-----SPLSDLSEG-STG-G-----------GPGPQALA-----
------------------------------------------------------------
-------------GGPTDSASSCRANGVA--TNDSVWCHPPAA--TA--SALDQRRPRYQ
TGAWSRQCRIEEEEEVEQELLSQ----SWGREMENSS--ATDPSNSSAWHRLRPTDGS--
SGQSSKVGTGMSKSASFAFEFPKDRSGIEVF-SPPPPPPK--SRHLLKMNKSSSDLEKVS
QGSAESLSPP-CRG-----VHVGFTTGSTDSLASDSRTCSDGGPSSEP-----------A
HSPTSSG---KKLFAP-VPFPSGSTEDVSPSGP-LQPPPLPQKKLVSRAAS-SPDGFFWT
QGSPKPRT---ASPKLNLSHSETNVCAHEESHFSYSSSPGSRHHHIFSSSEPLEKTFKG-
NGHWVPAPG--LAGGQSGFGSPSLQCKGVPS--A--SQLSVSSQASTGST-QLQLHSLLG
SISSKEGTYAKLGGLYAQSLVRLAAKCEDLFMGGQKKEL-HFNENNW-SLFKLTCNRPCC
D----SGDAIYYCATCSEDPGSTYAVKICKTPEPKA-APYC-SPSVPVHFNIQQDCGHFV
ASVPSSMLTSP--DA-PKDPQ-PAPPSHPPAQEQDCVVVITPEVPHQTASDFVRDSASSH
QS

PF00069 // ENSGT00460000041554_1_Domain_1 (1383, 1623)

EPEVYERRVCFLLLQLCNGLEHLKEHGIIHRDLCLENLLLVHCSPQASPGASPAA---
----------------PS-PSPAGAPAAC-PSASLAAAA-PV-----PAPAPACQGVPSE
KYLPRLIISNFLKAKQKPGG----TTNLQQKKSQARLAPEIVSASQYRKFDEFQTGILIY
ELLHQPNPFEVRARLREQDYRQEDLPPLPALSLYSP---GLQQLAHLLLEADPIKRIRIG
EAKRVLQCLLWGPRRELVEQPGTSEEVLCGTLHNWIDMKRALMMMKFAERAADRRRGVEL
EDWLCCQYLAAAEPGALLQSLKLLQLL---------

-------------------------MHQTLRLNPESLKMSACSDFVEHIWKPGSCKNCFC
LRSDHQLVAGPPQPRA-----GSLPP-PPR--LPPRPENCRLEDEGV--NSSPYSKPTIA
VKPTMMSSEASDVWTEANLS---AEVSQVIWRRAPGKLPLPK--QEDAPVVYLGSFRGVQ
KPAGPSTSPDGNS-RCPPAYTMVGLHNLEPRGERNIAFHPLSFPDEKAGHKEKPSFPYQD
-RPSTQESFRQKLAAFAG-TTSGCHQGPG------PLR--ESLPSEDDSDQRCSPSGDSE
GGEYCSI-LDCCPGSPVAKAASQSAGSRGRHGGRDCSP-TCCEQGKCAGPAEQ-------
-------EKRGPSFPKE--------CCSQGPTA-HPSCLGPKKPSLTSEAAISSDGLSCG
SGS--GSGASSPFVPHLESDYCSLMKEP-----------APEKQQDPGCPGVTPSRCIGL
TGEPQPPAHPREDTQPEPIYAESTKRKKAAPVPS-KPQTKTEHAAAAQG------QGQVW
-TGNAWAQKTASGWGRDS--PDPTLQVSATITVMAAHPEEDHRTIYLSSPDSAVGVQWPR
GPVSQNSEVGE------EE--TSA----EQGLSSRESH-----AHSASESKPKERPAIPP
KLSKSSPGGSPVSPSAGGPPVSPLADLSDGSSGG------------SGIGPQPPS-----
------------------------------------------------------------
-------------RSPADPAPPCRTNGVT--ISDPSRCPQPAA-----SAALEQRRPRFQ
AGTWSRQCRIEEEEEVEQELLSH----SWGRETKNG---PTDHSNSTTWHRLHPTGGS--
SGHNSKVGTGMSKSASFAFEFPKDRSGIETF-SPPPPPPK--SRHLLKMNKSSSDLEKVS
QGSAESLSPS-FRG-----VHVSFTTGSTDSLASDSRTCSDGGPSSEL-----------A
HSPTNSG---KKLFAP-VPFPSGSPADVSPSGP-LQPPPLPQKKIVSRAAS-SPDGFFWT
Q--------------------ETN--VHDESHFSYLLSPGNRHRPVFSSSDPLEKAFKG-
SGHWVPAAG--LAGNRGGCRSPGLQCKGAPS--ASSSQLSVSSQASTGST-QLQLHGLLS
NISSKEGTYAKLGGLYTQSLARLVAKCEDLFMGGQKKEL-HFNENNW-SLFKLTCNKPCC
D----SGDAIYYCATCSEDPGSTYAVKICKTPEPKT-VSYC-SPSVPVHFNIQQDCGHFV
ASVPSSMLTSP--DA-PKDPV-PAVSAHAPAQ

PF07714 // ENSGT00460000041554_1_Domain_0 (1353, 1423)

EQDCVVVITREVPHQTASDFVRDSAASH
QAEPEAYERRVCFLLLQLCNGLEHLKEHGIIHRDLCLENLLLVHCTLQAAPGPVPAPAPA
A-------A----------AAP-----TC-SSAALPAGGTLSPA-----AGPASPEGPRE
KQLPRLIISNFLK----PGG----TPNLQQKKSQARLAPEIV------------------
SLLHQPNPFEVRAQLRERDYRQEDLPPLPAVSLYSP---GLQQLAHLLLEADPIKRIRIG
EAKRVLQCLLWGPRRELVQQPGTSEEALCGTLHNWIDMKRALMMMKFAEKAVDRRRGVEL
EDWLCCQYLASAEPGALLQSLKLLQLL---------

------------------------------------------------------------
------------------------------------------------------------
----------------------------VVWRPAPSKLPLQK--QEDTPRAYLSSFRGAQ
KPRGPLASAD-SSPRCPPDYTTVSLHSPESRGERNLTFLPVSVPDEKGGREDKTTFSYQE
-SPSAQESFRQKLAAFAG-MASGCSKGSGPQ-----LPR-ESLPSEEDSDQRCSPSGDSE
GGEYCSI-LDCCPRSPVAKVTSQAEGSRPRPGGGARSP-MPWERGTRPLPPVE-------
-------EKRVLSFPRE--------CCNQDLTENASSRPGPKKPALM-EAASSSDGLSCG
SG---SSGASSPFAPALESDYCSLIKDP-----------KPEKQVESACHTGISSRCPGL
TGELQPPAHPREAVQPDPIYAESTRGETV-PELS-XXWARAE------------------
-QINTWAQKTVPGWGQGREGPERAAQVAATITVMAAHPEEDHRTIYLSSPDSAVGVQWPR
GPVSQDCEA--------GEEATPA----GQGLSPGDSR-----PHDASENLPTGRPAIPP
KLSRSSPGGSPVSPST-----SPLADPSEGSSSG-------------APGPQPAP-----
------------------------------------------------------------
-------------IGPADPAPCCHTNGLA--TSDPGRRLPPAAT-----PTADQRRPRYQ
TGAWSRQCRIEEEEEVEQELLSR----SWGREMGNG---LPDSSSSSTWHRLRPAAAS--
CGQNGKAGAGMSKSASFAFEFPKDRSGIEAF-SPPPPPPK--SRHLLKMNKSSSDLEKVS
QGSAESLSPS-FRG-----VHVSFTAGSTDSLASDSRTCSDGGPSYEP-----------I
HSPTNSG---KKLFAP-VPFPSGSTEDVSPSGP-LQPPPLPQKKVVSRTAS-SPDGVFWT
QGSSKPRT---ASPKLNLSHSETNVCVHDESPF-YSPSPVSRQHRVFS-SEPLEKAFKG-
HGHWAPAPXXXXXXXXXXXXXXXXXXXXXXX---------XXXXXXXXXX-XXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXCSE--PGSYAVKICKTPEPKA-TSCC-SPSVPVHFNIQQDCGHFV
ASVPSSMLGSP--NV-PRDPL-PALPAQTPAQEQDCVVVITREVPHQTAADFVRESAASH
RAEPEVYERRVCFLL

PF07714 // ENSGT00460000041554_1_Domain_2 (1396, 1422)

LQLCNGLEHLKEHSIIHRDLCLENLLLVHCTPQASPVPLPAPSAA
PTAIP---------------------STG-PSAALPANVTPG-----LPAAPTCRGGPGE
KHLPRLIISNFLKAKQKPGG----TANPQQKKSQARLAPEIVSASQYRKFDEFQTGILIY
ELL-QPTRLEVRAQLRRDYRQRLPLP----------------------------------
------------------------------------------------------------
------------------------------------

-------------------------MHQTLQLNPESPKMSACSDFVEHIWKPGSCKNCFC
LRSDHQLVASHPQPRA-----GSLPP-PPR--LPPRPEHCRLEDEGV--NSSPYSKPTIA
VKPTMMSSEASDVWTEANLS---AEVSQVIWRQAPGKLPLPK--QEDVPIVYLGSFRSVQ
KPAGPSASAD-GSARCPPAYAMVGLHNLDARGERSMAFHPVNFPDDKGRREDKPSVPYQD
-LPSAQESFRQKLAAFAG-TTSGCHKGPS-----QPLR--ESLPSEDDSDQRCSPSGDSE
GGEYCSI-LDYCPGSPVAKDASQAEGHRGRRGGGDCSP-TCWEPGTCARPAED-------
-------KKRVLSFPRE--------CCSQGQPA-NPTCLGPKKPSLTLEAATSSDGLSCG
S-G--SSRASSPCAPHLESDYCSLMKEP-----------TPGKQQDAGCHGVTSSRCLGL
AGEPPPPAHPREAAQPEPIYAESTKRKKAVPVPS-RPQAKAEQAPAAQAQGQ----GRT-
-GNSVWSQKTAPGWGRDS--PDPAPQVATTITVMAAHPEEDHRTIYLSSPDSAVGVQWPR
GPVSQDSE---V-----GQEETSA----RQGLSSRESR-----AQDASRNTPKGRPAIPP
KLSKSSPGGSPVSPSA-----SPLADLSEGSSGGGG----------GGVGPQPAS-----
------------------------------------------------------------
-------------RGPTDPASSCRTNG------DPARCPPPASASSS--STLDQRRPRFQ
TGTWSRQCRIEEEEEVEQELLSQ----SWGREMKNG---TMDHSHSTTWHRLHLTDGS--
SGQNSKVGTGMSKSASFAFEFPKDRSGIETF-SPPPPPPK--SRHLLKMNKSSSDLEKVS
QGSAESLSPS-FRG-----VHVSFTTGSTDSLASDSRTCSDGGPSYEP-----------A
HSPTISG---KKLFAP-VPFPSGSTEDVSPGGP-LQPPPLPQKKIVSRAAS-SPDGFFWT
QGSPKPRT---ASPKLNLSHSETN--VHDESHFSYSFSPGNRHRHGFSSSEPLEKAFKG-
SGHWVPAPG--LAGNKSSCGSPGLQCKGAAS--ASSSQLSVSSQASSGSA-QLQLHSLLS
SISSKEGTYAKLGGLYTQSLARLVAKCEDLFMGGQKKEL-HFNENNW-SLFKLTCNKPCC
D----SGDAIYYCATCSEDPGSTYAVKICKTPEPKT-ASYC-SPSVPVHFNIQQDCGHFV
ASVPSSMLTSP--DA-PKDPA-PAPPSQPPAQEQDCVVVITREVPHQTASDFVRDSVASH
QVEPEA

PF00069 // ENSGT00460000041554_1_Domain_1 (1387, 1623)

YERRVCFLLLQLCNGLEHLKEHGIIHRDLCLENLLLVHCAPQAAPATNAPPAS-
-----------------------VPAAPG-PSATVPAGATPS-----PAAGPAAEGAPGE
KQLPRLIISNFLKAKQKPGG----TPNLQQQKSQARLAPEIVSASQYRKFDEFQTGILIY
ELLHQPNPFEVRARLRERDYRQEDLPPLPALSLYSP---GLQQLAHLLLEADPIKRIRIG
EAKRVLQCLLWGPRRELVEPPAASEEALCGTLHNWIDVKRALVMMKFAEKAVDRRRGVEL
EDWLCCQYLASAEPGALLQSLK--------------

-------------------------MHQTLCLNPESLKMSACSDFVEHIWKPGSCKNCFC
LRSDHQLVAGPPQPRA-----GSLPP-PPR--LPPRPENCRLEDEGV--NSSPYSKPTIA
VKPTMMSSEASDVWTEANLS---AEVSQVIWRRAPGKLPLPK--QEDAPVVYLGSFRGVQ
KPAGPSTSPDGNS-RCPPAYTMVGLHNLEPRGERKIAFHPVSFPDEKAGHKENPSFPYQD
-RPSTQESFRQKLAAFAG-TTSGCHQGPG------PLR--ESLPSEDDGDQRCSPSGDSE
GGEYCSI-LDCCPGSPVAKAASQTAGSRGRHGGRDCSP-TCWEQGKCSGPADQ-------
-------EKRGPSFPKE--------CCSQGPTA-HPSCLGPKKLSLTSEAAISSDGLSCG
SGS--GSGASSPFVPHLESDYCSLMKEP-----------APEKQQDLGCPGVTPSRCLGL
TGEPQPLAHPREATQPEPIYAESTKRKKAAPVPS-KSQAKIEHAAAAQG------QGQVC
-TGNAWAQKTASGWGRDS--PDPTPQVSATITVMAAHPEEDHRTIYLSSPDSAVGVQWPR
GPVSQNSELGE------EE--TSA----GQGLSSRESH-----AHSASESKPKERPAIPP
KMSKSSPVGSPVSPSAGGPPVSPLADLSDGSSGG------------SSIGPQPPS-----
------------------------------------------------------------
-------------QGPADPAPSCGTNGVT--ISDPSRCPQPAA-----SSALEQRRPRFQ
AGTWSRQCRIEEEEEVEQELLSH----SWGRETKNG---PTDHSNTTTWHRLHPTDGS--
SGQNSKVGTGMSKSASFAFEFPKDRSGIETF-SPPPPPPK--SRHLLKMNKSSSDLEKVS
QGSAESLSPS-FRG-----VHVSFTTSSTDSLASDSRTCSDGGPSSEL-----------A
HSPTNSG---KKLFAP-VPFPSGSTEDVSPSGP-LQPPPLPQKKTVSRAAS-SPDGFFWT
QGSPKPRT---ASPKLNLSHSETN--VHDESHFSYSLSPGNRHHPVFSSTDPLEKAFKG-
SGHWLPAAG--LAGNRGGCGSPGLQCKGAPS--ASSSQLSVSSQASTGST-QLQLHGLLS
NISSKEGTYAKLGGLYTQSLARLVAKCEDLFMGGQKKEL-HFNENNW-SLFKLTCNKPCC
D----SGDAIYYCATCSEDPGSTYAVKICKTPEPKT-VSYC-SPSVPVHFNIQQDCGHFV
ASVPSSMLSSP--DA-PKDPV-PALPAHPPAQEQD

PF07714 // ENSGT00460000041554_1_Domain_0 (1356, 1423)

CVVVITREVPHQTASDFVRDSAVSH
QAEPEAYERRVCFLLLQLCNGLEHLKEHGIIHRDLCLENLLLVHCTLQAGPGPAPAPAPA
PAPAPAPAA----------AAP-----PC-SSAAPPAGGTLSPA-----AGPASPEGPRE
KQLPRLIISNFLKAKQKPGG----TPNLQQKKSQARLAPEIVSASQYRKFDEFQTGILIY
ELLHQPNPFEVRAQLRERDYRQEDLPPLPALSLYSP---GLQQLAHLLLEADPIKRIRIG
EAKRVLQCLLWGPRRELVQQPGTSEEALCGTLHNWIDMKRALMMMKFAEKAVDRRRGVEL
EDWLCCQYLASAEPGALLQSLKLLQLL---------

-------------------------MHQTIPVNPESPKMSACSDFVEHIWKPGSCKNCFC
LRTDHQPAPGRPQPRA-----GSLPP-PPR--LPPRPESGRPEDEGL--SSSPYSKPTIA
VKPTMMSSDASDGWTEAGVS---ADVAQVIWRRAPGKLPLPK--QEDVPVVYLGSFRGVQ
KPAGPLAPADGGHPRCPPAYAMVGLHSLEPRGERSVAFHPVSLPDEKLGREDKPTIPYQE
-LTSPQESFRQKLAAFAE-MTSGCHKGPR------PLR--ESLPSEDDSDQRCSPSGDSE
GGEYCSI-LDCCPGSPGGQDASQAEDSGRRQGCGDCSP-ACWEQGMCSKPTEE-------
-------ERRALSFPRE--------CRSQGPTE-NPPRLGPKKQSLTSEAASSSDGLSCG
S-A--SSRASSPLVPQHESDSCSLMKAP-----------GPGKQQDSGCHGVASSRCLGL
TGEPQAPSHPGETAQPEPIYAESTKRKKAVPVPS-RPQAKAEQAAAAQ------GQGQVR
-MANTWAQKTTSGWGQDREGPEVAPQVAATITVMAAHPEEDHRTIYLSSPDSSVGVQWPR
GPLSQAPE--A------GEGEPSA----GQGLSSRESR-----HHGASESTPKGRPAIPP
KLSKSSPAGSPVSPPP-----QP--SLSEG-N-S-G-----------VTGPQPPS-----
------------------------------------------------------------
-------------RGPADPASSCRANGVP--ASDSARGPPPAT--AT--SASDQRRPRYQ
TGAWSRQCRIEEEEEVEQDLLSQ----SWGRGVDGG---PMGPCSSSTWLRPRPTDGA--
SGPKSKAGTGMSKSASFAFEFPKDKSGIEAF-SPPPPP-P--SRHLLKMNKSSSDLEKVS
QGSAESLSPS-FRG-----VHVSFTTGSTDSLASDSRTCSDGGPSSEL-----------T
HSPTSSG---KELFSP-VPFPSGSTEDVSPSGP-LQPPPLPQKKLVSRAAS-SPDGFFWT
QGSPKPRT---AGPKLNLSHSETNVCVHDESHFSYSSGPGSRLQHTFSASEPLEKTFKD-
NGPWGPAPG--LAGS------QSLQGKGVSS--AAASQLSVSSQASAGSA-QLQLHSLLS
SISSKEGTYTKLGGLYAQSLVRLVARCEDLFMGGQKKGL-HFSENNW-SLFKLACNKPCC
D----SGDAIYYCATCSEDPGSTYAVKICKTPEPKA-ASYC-SPSVPVHFNIQQDCGHFV
ASVPSSMLTSP--DA-PKDLL-SALPSHPPAQEQDCVVVITREVPHQTASDFVQDSATSH
QSEPEVYERRVCFLL

PF07714 // ENSGT00460000041554_1_Domain_2 (1396, 1422)

LQLCNGLEHLKEHGIIHRDLCLENLLLVHCAPQASPDPSS-----
----------------ALAPAPAATPSSC-PSAALPAGVTPT-----PPAGPACQGGPGE
KHLPRLIISNFLKAKQKPGG----STNLQQKKSQARLAPEIVSASQYRKFDEFQTGILIY
ELLHQPNPFEVRAQLREQDYRQEDLPPLPALSLYSP---GLQRLAHLLLQADPIKRIRIG
EAKRVLQCLLWGPRRELVEQPGTSEEALCATLSNWIDMKRALMMMKFAEKAVDRRRGVEL
EDWLCCQYLASAEPGALLQSLKLLQLL---------

-------------------------MHQTLRLKPGSLKMSACSDFVEHIWKPGSCKNCFC
LRSDHQLVAGPPQPRA-----GSLPP-PPR--LPPRPENCRLEDEGV--NSSPYSKPTIA
VKPTMMSSEASDVWTEAGLS---AEVSQVIWRRAPGKLPLPK--QEDAPVVYLGSFRGVQ
KPAGPSTSPDGNSPRCPPAYTMVGLHNLEPRGERNIAFHPVSFPDDKAGHKEKPSFPYQD
-RPSTQGSFRQKLAAFAG-TTSGCHQGPG------PLR--ESLPSEDDGDQRCSPSGDSE
GGEYCSI-LDCCPGSPVAKAASQVAGSRGRHSGRDGSP-TCWEQGKCAGPTEQ-------
-------EKRGLSFPKE--------CCSQGPTA-HPSCLGPKKASFTSEAATSSDGLACG
SGS--GSGASNPFVPHLESDYCSLMKEP-----------TPEKQQDLGCPGVASSRCLGL
TGEPQPPAHPREATQPEPIYAESTKRKKAAPLPS-KPQAKTEHAAAAQ------GQGQVW
-TGNAWAQKTASGWGQDS--PDPTPQVAATITVMAAHPEEDHRTIYLSSPDSAVGVQWPP
GPGSQNSEVGE------EE--TLA----RQGLSSRESH-----THSAKESKPKERPAIPP
KLSKSSPGGSPVSPSAGGPPVSPLADLSDGSSGS------------SGIGPQPPS-----
------------------------------------------------------------
-------------RGPADPIPPCRTNGVT--LSDPSRCPQPVT------SALDQRRPRFQ
AGTWSRQCRIEEEEEVEQELLSH----SWGRETKNG---PTDHSNSTTWHRLHPTDGS--
SGQNSKVGTGMSKSASFAFEFPKDRSGIETF-SPPPPPPK--SRHLLKMNKSSSDLEKVS
QGSAESLSPS-FRG-----VHVSFTTGSTDSLASDSRTCSNGGPSSEL-----------A
HSPTNSG---KKLFAP-VPFPSGSTEDVSPSGP-RQPPPLPQKKIVSRAAS-SPDGFFWT
QGSPKPQT---ASPKLNLSHSETN--VHDESHFSSSLSPGNRHHAVFSSSDPLEKAFKG-
SGHWVPAAG--LAGNRGGCGSPGLQCKGTPS--ASSSQLSVSSQASTGST-QFQLHGLLS
NISSKEGTYAKLGGLYTQSLARLVAKCEDLFMGGQKKEL-HFNENNW-SLFKLTCNKPCC
D----SGDAIYYCATCSEDPGSTYAVKICKTPEPKT-VSYC-SPSVPVHFNIQQDCGHFV
ASVPSSMLTSP--DA-PKDPV-PTLPAHPPAQEQDCVVVITREVPHQTASDFVRDSAASH
QAEPE

PF00069 // ENSGT00460000041554_1_Domain_1 (1386, 1623)

AYERRVCFLLLQLCNGLEHLKEHGIIHRDLCLENLLLVHCTPQAAPGPTPAT---
-------------------AAP-----PC-SSAALPAGGTLSPA-----AGPASPEGPRE
KQLPRLIISNFLKAKQKPGG----TPNLQQKKSQARLAPEIVSASQYRKFDEFQTGILIY
ELLHQPNPFEVRAQLRERDYRQEDLPPLPALSLYSP---GLQQLAHLLLEADPIKRIRIG
EAKRVLQCLLWGPRRELVQQPGTSEEALCGTLHNWIDMKRALMMMKFAEKAVDRRRGVEL
EDWLCCQYLASAEPGALLQSLKLLQLL---------

--------------------------------------MSACSDFVEHIWKPGSCKNCFC
LRSDHQPTAGHPKARA-----NSLPA-GTR--LPARPENCRLDDEGV--NGLAYSKPTIA
VKPTMMTSETSDLWTEANLS---AEVPKVNWRRTPGKLLLPK--QEDEPIVYLGSFRGLQ
KPAGPLACTD-GNSRCPPAYTMVGLHNLETRVDRNTAFQPVSFQEEKAGRGE--------
-LPSAHESFRQKLAAFAG-MTSSCPKGPRPCTSPQPLQ--ESLPSEDDSDQRCSPSGDSE
GGEYCSI-LDCCPEPKDTVHSTEG--S--GRRGGDCSP-TYREQGPHTRPTEE-------
-------EKQGLNFPRE--------CCGQGSTA-NPPRLGPKKPSLNSEAASSSDGMSCG
S-S--RSGASSPFAPHLENDYCSLVKEP-----------ATGKQQDSSCHFLASGKCVGQ
AVELQPPALPRDAVQPEPIYAESAKRKKAAPGPP-RPEPKKEQVAASH------SQGQVW
-TGDSWVQKTPPSWSQDREGANPAPQVATTITVIAAHPEEDHRTIYLSSPDSAVGVQWPR
GPSNQDLQ---A-----SEEEPLV----VQGLTSRESH-----PHVVTENTSKEKPAIPP
KLSKSSPGGSPVSPAA-----PPLTDHSDGNTGG------------SSVG-QLLS-----
------------------------------------------------------------
-------------RVPANLTSSCHTNGVAT-GGDPAKCPPPATSS----SVLDQRRPRYQ
TGAWSRQCRIEEEEEVGQELLSQ----SWGRELENG---TVDHSNASTWHRLHPI-D-GS
SGQNSKTNSGMSKSASFAFEFPKDRGRLEAF-SPPPPPPK--SRHLLKMNKSSSDLEKVS
QSSAESLSPS-FRG-----AHVSFTTGSTDSLASDSRPCSDGGPSYEP-----------S
HSPTISG---KKLFAP-VPFPSGSTEDVSPGGGPAQPPPLPQKKIVSRAAS-SPDGFFWT
QGSPKPRT---ASPKLNLSHSETNVCAHDEPPFNSSLNSGNRSHHVFSSSEPLEKAFKG-
NAPWAPALG--LANSKGGCGSPGLQCRAATS--TSSSQLSVSSQASSSST-QLQLHSLLS
SISSKEGTYAKLGGLYTQSLARLVTKCEDLFMGGQKKEL-RFNENNW-SLFKLTCNKPCC
D----SGDAIYYCATCSEDPGSIYAVKICKTPEPKS-ASYC-SPSVPVHFNIQQDCGHFV
ASVPSSMLASPSPDTSSKDTA-PAASPQHPAQEQDCVVVITREVPHQTASDFVRDSMVSH
R

PF00069 // ENSGT00460000041554_1_Domain_1 (1382, 1623)

TEPEVYERRVCFLLLQLCNGLEHLKEHGIIHRDLCLENLLLAHCNPQSSPGPSATPTVP
T------------------------------------ATSRCP-SAAPAATTACQGGPGE
KHLPRLIISNFLKAKQKPGG----TTNLQQKKSQARLAPEIVSASQYRKFDEFQTGILIY
ELLHQPNPFEVRAQLRERDYRREDLPPLPTLSLYSP---GLQQLAHLLLEADPIKRIRIG
EAKRVLQCLLWGPRRELVEQPCTSEEVLCNTLHNWIDMKRALMMMKFAEKAVDRRRGVEL
EDWLCCQYLASAEPAALLQSLKLLQLL---------

-------------------------MHQTLRLNPESPKMSACSDFVEHIWKPGSCKNCFC
LRSDHQLVAGPPQPRA-----GSLPP-PPR--LPPRPENCRLEDEGV--NSSPYSKPTIA
VKPTMMSSEASDVWTEANLS---AEVSQVIWRRAPGKLPLPK--QEDAPVVYLGSFRGVQ
KPAGPSTSPDGNS-RCPPAYTMVGLHNLEPRGERNIAFHPVSFPDEKAGHKEKPSFPYQD
-RPSTQESFRQKLAAFAG-TTSGCHQGPG------PLR--ESLPSEDDSDQRCSPSGDSE
GGEYCSI-LDCCPGSPVAKAASQTAGSRGRHGGRDCSP-TCWEQGKCSGPAEQ-------
-------EKRGPGFPKE--------CCSQGPTA-HPSCLGPKKPSLTSEAAISSDGVSCG
SGSRSGSGASSPFVPHLESDYCSLMKEP-----------APEKQQDPGCPGVTPSRCLGL
TGEPQPPAHPREAPQPEPIYAESTKRKKAAPVPS-KSQAKTEHAAAAQGQGQGQGQGQVC
-TGNAWAQKTPSGWGRDS--PDPTPQVSATITVMAAHPEEDHRTIYLSSPDSAVGVQWPR
GPVSQNSEVGE------EE--TSA----GQGLSSRESH-----AHSARESKPKERPAIPP
KLSKSSPVGSPVSPSAGGPPVPPLADLSDGSSGG------------SSIGPQPPS-----
------------------------------------------------------------
-------------RGPADPAPPCRTNGVT--ISDPSRCPQPAA-----SSALEQRRPRFQ
AGTWSRQCRIEEEEEVEQELLSH----SWGRETKNG---PTDHSNSTTWHRLHPTDGS--
SGQNSKVGTGMSKSASFAFEFPKDRSGIETF-SPPPPPPK--SRHLLKMNKSSSDLEKVS
QGSAESLSPS-FRG-----VHVSFTTGSTDSLASDSRTCSDGGPSSEL-----------A
HSPTNSG---KKLFAP-VPFPSGSTEDVSPSGP-LQPPPLPQKKIVSRAAS-SPDGFFWT
QGSPKPRT---ASPKLNLSHSETN--VHDESHFSYSLSPGNRHHPVFSSSDPLEKAFKG-
SGHWVPAAG--LAGNRGGCGIPGLQCKGAPS--ASSSQLSVSSQASTGST-QLQLHGLLS
NISSKEGTYAKLGGLYTQSLARLVAKCEDLFMGGQKKEL-HFNENNW-SLFKLTCNKPCC
D----SGDAIYYCATCSEDPGSTYAVKICKTPEPKT-VSYC-SPSVPVHFNIQQDCGHFV
ASVPSSMLTSP--DA-PKDPV-PALPAHLPAQEQDC

PF07714 // ENSGT00460000041554_1_Domain_0 (1357, 1423)

VVVITREVPHQTASDFVRDSEASH
QAEPEAYERRVCFLLLQLCNGLEHLKEHGIIHRDLCLENLLLVHCTLQAAP--------------APAA----------AAP-----PC-SSAATPAGGTLSPA-----AGPASPEGPREKQLPRLIISNFLKAKQKPGG----TPNLQQKKSQARLAPEIVSASQYRKFDEFQTGILIYELLHQPNPFEVRAQLRERDYRQEDLPPLPALSLYSP---GLQQLAHLLLEADPIKRIRIGEAKRVLQCLLWGPRRELVQQPGTSEEALCGTL

PF00069 // ENSGT00460000041554_1_Domain_1 (1359, 1623)

VITREVPHQTASDFVRDSEASHQAEPEAYERRVCFLLLQLCNGLEHLKEHGIIHRDLCLENLLLVHCTLQAAP---------
-----APAA----------AAP-----PC-SSAATPAGGTLSPA-----AGPASPEGPRE
KQLPRLIISNFLKAKQKPGG----TPNLQQKKSQARLAPEIVSASQYRKFDEFQTGILIY
ELLHQPNPFEVRAQLRERDYRQEDLPPLPALSLYSP---GLQQLAHLLLEADPIKRIRIG
EAKRVLQCLLWGPRRELVQQPGTSEEALCGTLHNWIDMKRALMMMKFAEKAVDRKRGVEL
EDWLCCQYLASAEPGALLQSLKLLQLL---------

--------------------------------------MSACSDFVEHVWKPGSCKNCFC
LRSDHQLTAGHPKARA-----SSLPA-ITR--LPARPENCRLEDEGV--NGLSYSKPTIA
VKPTMMSSEASDLWTEASLS---AEVPKVSWRRAPGKLPFQK--QEDGPIVYLGSFRGMQ
KSSGALACTD-SNSCCPPAYTMVGLHNLDAQVDRSPAFQPVSFQEEKAGREE--------
-LPSAQESFRQKLAAFAG-MTSSCPKSPRPCPSPQPPR--ESLPSEDDSDQRCSPSGDSE
GGEYCSI-LDCCPESKEAVHSTEG--S--GRRGGDFSP-MCWEQGTCTRPTEE-------
-------EKRLLNLPRE--------CCGQGSTS-NPPRLGPKKPSLNSEAASSSDGLSCG
S-G--SSGASSPFAPHLENDHCSLVKEP-----------VLGKQQDSSCPVITSGKCVGQ
AGELQPPALPREAVQPEPIYAESTKRKKAVPVPS-RPETKAEQVAAGH------SQGQVR
-TGDTWAQKTSSGWSQDREGTNMAPQVATTITVIAAHPEEDHRTIYLSSPDSAVGVQWPH
GPSSQDLQ---A-----GEEESLV----IQGLSSRESH-----PHNVTENTPKEKPAIPP
KLSKSSPGGSPASPAA-----SPLADHSDGNTGS------------SCSGPQLLS-----
------------------------------------------------------------
-------------RVPTNRTSSCQTNGVA--TGDPAKCPPPVTSS----SALDQRRPRYQ
TGAWSRQCRIEEEKEVGQELLSQ----SWGREVENG---NTDHLNSSTWHRLYPT-D-GF
SGQNSKTSSGMSKSASFAFEFPKDRGRMEAF-SPPPPPPK--SRHLLKMNKSSSDLEKVS
QSSAESLSPS-FRG-----AHVSFTTGSTDSLASDSRTCSDGGPSYES-----------A
HSPTISG---KKLFAP-VPFPSGSTEDVSPS-GPAQPPPLPQKKIVSRAAS-SPDGFFWT
QGSPKPPT---ASPKLNVSHSETNVCVHDELPFSYSLNSGDPTHRVFS-SEPLEKAFKG-
SGPWAPALG--LAGSKGGCGSPGLQGRTATS--SSSSQLSVSSQASSSST-QLQLHSLLS
SISSKEGTYAKLGGLYTQSLARLVTKCEDLFMGGQKKEL-RFNENNW-SLFKLTCNKPCC
D----SGDAIYYCATCSEDPGSTYAVKICKTPEPKS-ASYC-SPSVPVHFNIQQDCGHFV
ASVPSSMLASP--DTSSKDNV-QPAPSHSPSQEQDCVVVITREVPHQTASDFVRDSTASH
RA

PF00069 // ENSGT00460000041554_1_Domain_1 (1383, 1623)

EPEVYERRVCFLLLQLCNGLEHLKEHGIIHRDLCLENLLLAHCSPQGSPGPSATPTAP
---------------------------------------SCCP-SATPTATAACQGGPGE
KHLPRLIISNFLKAKQKPGG----TTNLQQKKSQARLAPEIVSASQYRKFDEFQTGILIY
ELLHQPNPFEVRAQLRERDYRREDLPPIPTLSLYSP---GLQQLAHLLLEADPIKRIRIG
EAKRVLQCLLWGPRRELVEQPCTSEEVLCNTLNNWIDMKRALMMMKFAEKAVDRRRGVEL
EDWLCCQYLASAEPGALLQSLKLLQLL---------

-----------------------------------IPKMSACSDFVEHIWKPGSCKNCFC
LWSDHQLAAGCAQPRA-----GSLPP-PPR--LPPRPENCRLEDDSV--NSSPYSKPTIA
VKPTMMSSEASDVWTEASLS---AEVSQVIWRRPSGKLSLPK--QEDVPIVYVGSFRGVQ
KPAGPSVSPDSNSRCSPPAYTMVGLHNLEARGERNITFHPVSFPDEKVGREDKPSFPHPV
-LPSAQESFRQKLAALAG-ATSGCHQGPG------PLR--ESLPSEDDSDQRCSPSGDSE
GGEYCSI-LDCCPESTVTKD--QTEGSRGRRGTGDCSP-TCWEQRTCAGPTEE-------
-------EKQAPSFPRE--------CCSQGTTA-NLPRLGPKKPSLTSDAATSSDGLSCG
S-G--SSGASSPFAPHLESDYCSLMKEP-----------LPGKEQDPGCHGVTSSKCLGL
TGESQSQAHPKEPAQPEPIYAESTKRKKAVPAPS-RPQAKAEQGAAAQ------GKGQVW
-TSKPWALKTASGWSQDS--PDPALQVAATITVMAAHPEEDHRTIYLSSPDSAVGVQWPR
GPVSQDPE--A------GQEETST----GQVLSSRNSH-----AHHAIENTPKGKPAIPP
KLSKSSPGGSPVSPSA-----FPLTDLSEGSSGG-G----------SGSGLPPAS-----
------------------------------------------------------------
-------------RGPTDPVSSCRTNGIT--ASDPARCPPPAA--TS--SASDQRRPRFQ
TSTWSRQCRIEEEEEVEQELLSQ----SWGREMKNG---PTDHSNSTTWHRLHYPAE-GS
SGQNSKVGTGMSKSASFAFEFPKDRSRIETF-SPPPPPPK--SRHLLKMNKSSSDLEQVS
QGSAESLSPS-FRG-----VHVSFTTGSTDSLASDSRTCSDGGPSYEP-----------A
HSPTNGG---KKLFAL-VPFTSGSTEDVSPSGP-VKPPPLPQKKIVSRAAS-SPDGFFWT
QGSPKPRT---TSPRLNLSHSETN--VHDESHFSCSLSSGSRHHHTFSSSEPLEKAFKG-
NGHWVPAAG--LVGSRSGCGSPSLQCKGAPS--ASSSQLSVSSQTSTGST-QLQLHSLLS
SISSKEGTYAKLGGLYTQSLARLVAKCEDLFMGGQKKEL-HFNENNW-SLFKLTCNKPCC
D----SGDAIYYCATCSEDPGSTYAVKICKTPEPKT-ASYC-SPSVPVHFNIQQDCGHFV
ASVPSSMLASP--DA-PKDPA-PALPSHPPAQEQDCVVVITREVPRQTASDFVRDWAASH
QAEPE

PF00069 // ENSGT00460000041554_1_Domain_1 (1386, 1623)

AYERRVCFLLLQLCNGLEHLKEHGIIHRDLCLENLLLVHCSPQAAPGPCPAAPAP
-------------------------------AATLPASGAPG-----PPAGPPCPEGPGD
KQLPRLIISNFLKAKQKPGG----TSNLQQKKSQARLAPEIVSASQYRKFDEFQTGILIY
ELLHQPNPFEVRTQLRERDYRQEDLPPLPALSLYSP---GLQQLAHLLLEADPIKRIRIG
EAKRVLQCLLWGPRRELVGQPGASEEALCGTLHNWIDMKRALMMMKFAEKAVDRRRGVEL
EDWLCCQYLASAEPGALLQSLKLLQLL---------

--------------------------------------MSACSDFVEHIWKPGSCKNCFC
LRSDHQLAAGRPQPRT-----GSLPP-PPR--LPPKS----VEDEGV--NGSPYCKPTIA
VKPTMMSSEAADVWTEAGLG---AEASQVIWRRAHGKLPLPK--QEDVPIVYLGSFRGIQ
KPAGPSVCKD-GSSHCPPAYAMVGLHSLQAQGERNMAFHPVSFPDDKA------------
-LPSAQESFRQKLAAFAG-MTSGCHKGSRPCPSPQPLQ--ESLPSEDESDQRCSPSGDSE
GGEYCSI-LDCCPRSPVTKDTTHAESSQGRCGGGSSSP-MCWEQGTCAGPPEE-------
-------GKQSPSSPRE--------CCGQSPSA-NAPHLGPKKLSLNSEAASSSDGLSCG
S-G--SSGASSPFTPHLESEYCSLVKEA----------VLPGKQQDSVCHVVTSDRCP--
--DSQPPAHPKEAAQPEPIYAESTKRKKAVPVPS-RAQVKAEQSAPA--------QGQVR
-TGDARAQKTPYVWSRDREGSDMAPQVSATITVMATHPEEDHRTIYLSSPDSAVGVQWPR
GPVGQDLE---A-----GKEGTAV----GQGPSSKESH-----PQHRSENAPQARPAIPP
KLSKSSPCGSPASPST-----SAMADPSEGSSD--------------SKGPQSSS-----
------------------------------------------------------------
-------------RALADPLSSHRNS-------DLARCPPPAAS----TSALDQRRPRYQ
TGAWSRQCRIEEEEEVEQELLSQ----SWGREMDNC---SVDHSNSSTWHRLHPTDSS--
SGQNSKVGTGMSKSASFAFEFPKDRSRIEVF-SPPPPPPK--SRHLLKMNKSSSDLEKVS
QGSAESLSPS-FRG-----VHVSFTTSSTDSLASDSRTCSDGGPSSEP-----------T
HSPTISG---KKLFAP-VPFPLGSTENVSPSGS-VQPPPLPQKKIVSRAAS-SPDGVFWT
QGSPKPRA---ASPKLNLSHSETNVSVHDESHFGYSLSPGSRHHPIFSSSEPLEKAFKG-
SGSWVPALG--LSGSKSSCGSPSLQCGAAPS--TSSSQLSVSSQVSSSST-QLQLHSLLS
SISSKEGTYAKLGGLYTQSLARLVAKCEDLFMGGQKKEL-HFNENNW-SLFKLTCNKPCC
D----SGDAIYYCATCSEDPGSTYAVKICKTPEPKT-ASYC-SPSVPVHFNIQQDCGHFV
ASVPSSMLTSP--DM-TKDPL-PAAASQPPAQEQDCVVVITREVPYQTASDFVRDSAASH
QAEPE

PF00069 // ENSGT00460000041554_1_Domain_1 (1386, 1624)

AYERRVCFLLLQLCNGLEHLKEHGVIHRDLCLENLLLVHCSPQACPASCPATPAL
S----------------------TAASA-----------------------RPTTGAPSE
KHLPRLIISNFLKAKQKPGC----TSNLQQKKSQARLAPEIVSASQYRKFDEFQTGILIY
ELLHQPNPFEVRAQLREQDYRREDLPPLPTLSLYSP---GLQQLAHLLLEADPIKRIRIG
EAKHVLQCLLWGPRRELVEQPGSSEEVLCGTLHNWMDMKRALMMMKFAEKAVDRRRGVEL
EDWLCCQYLAAAEPVGLLQSLKLLQLL---------

-------------------------MHQAIPVTSRLPKMSACNEFVEHIWKPGSCKNCFC
LQSAHQQSPAP---TA----------------QPVRPGRTPPEEEGF--NLSPCSKPTIA
VKPTMMSAEGADMGSEAPQPSLTLGLAQVLWRPTPSKLPLQEPRDAL------RTFSGRD
-----------LGPCSLAASSRLGLLRLARPGSRDAP------SPDSGGHVEGASPPGQE
SVLPAYQSFHQKLATFLERAGGSA--APH---------SGIVPTALRAKELQSSPQRDPE
GGEYCSI-ADCCPTSTLPPAAGP--GPGRGHGKDGPVPRGA---DEAVSPSE--------
-------EGWGPSL------RK-EHCCQSRPEHVHPLALAQRKLPQALEAASLSDGPS--
----------SLTAGYMDGDYCSLSRQPEPRW-----------PCGPGPRGESPSR----
--SPGSPTQSSECSPPEPIYAEVTKRKKPYSASSDLP-GTNKQSGCDPGQG---------
--------LASDIWGQGRARPDTGAQVAATVTIVAAHPEDDRRTICLRSPDSAVGVQWPC
EHVGPGLDDTPT--QI-------------L-----ELPPHNHLPGPRGEDVERRCPAIPP
KVCKGSPGGAHGSPEG-----SPLVQFKDGHWNQPAVS-----------GLTDVS-----
------------------------------------------------------------
-----------------A---SLSSPG----TRDLIRGLLPAQ-----SSSWDQRRPRFQ
VGARSYQGRIEEEEEEEQQLDSGPSSLGTAREMETTS--------HTRRPRAESI-SEQP
SRGDRGTGLGMSKSASFAFEFPKDRSEVEKF-CPPPPPPK--SRHLLRMNKSSPDLEQAS
HGVAESLSPPGFGG-----LHVHFTTGSTDSLTSDSQSCSEGGLS-----------LEPA
CCPSS--------AP--VASPVQPEEDESTHGP-LQPPPLPQKRTVSRAAS-SPDGLFLT
QGSLVHRT---TSPRLNPSHSETSICFPEDSRSTG-----R-----------------G-
---------------------PEAQLPGSQGLSLASSQLSVSSQTSASSCPPQQQPSLLA
SIASKEATYAKLSDLYTQSLLRLAARCEQHFMGDQGSEPLRFSENSW-SLFKLTRNQPCC
R----SGDAVYYCATCSQDPSRAYAVKICKMLVSKE-APYSDDLSVPIHFNLQQDCGHFV
ASVPSSMLLCA-----------------GEPQD

PF00069 // ENSGT00460000041554_1_Domain_1 (1354, 1624)

QDCVVVITREVPHQTAADFVKDSASRH
WAEPEAYERRVCLLLLQLCQGLESLKEQSITHRALCLENLLLVPCPG-------------
-------------------------------------------------------TSPGD
QSLPRLLISNFLQAKQQPRGGG--GVDEQQRRTQARLAPEIVAAAQYKKFDEFQTGILIY
ELLHQPNPFEEQAQLQRQDYQAEDLPPVPTLSLYSA---GLQRLAHRLLEADPIKRLHIA
EAKRALQCLLWGPRRELL----------QGQLQNWLHMKRALLLMKLAEKALDEQATIEL
EDWLCCQYLASSEPGALQQTLRLLQPL---------

-------------------------MHQTLRLKPESLKMSACSDFVEHIWKPGSCKNCFC
LRSDHQLVAGPPQPRA-----GSLPP-PPR--LPPRPENCRLEDEGV--NSSPYSKPTIA
VKPTMMSSEASDVWTEASLS---AEVSQVIWRRAPGKLPLPK--QEDAPIIYLGSFRGVQ
KPAGPSASPDGNSPRCPPAYTMVGLHNLEPRGERNIAFHPVSFPDEKAGHKEKPSFPYQD
-RPSTQESFRQKLAAFAG-TTSGCHQGPG------PLR--ESLPSEDDGDQRCSPSGDSE
GGEYCSI-LDCCPGSPVAKAASQAAGSRGRHSGRDGSP-TCWEQRKCAGPTEQ-------
-------EKRGLSFPKE--------CCSQGPTA-HPSCLGPKKASFTSEAATSSDGLSCG
SG----SSASNPFVPHLESDYCSLMKEP-----------APEKQQDLGCPGVASSRCLGL
TGEPQPPAHPREATQPEPIYAESTKRKKAALVPS-KPQAKTEHAAAAQGQ----GQGQVW
-TGNAWAQKTASGWGQDS--PDPTPQVAATITVMAAHPEEDHRTIYLSSPDSAVGVQWPR
GPVSQNSEVGE------EE--TLA----RQGLSSRESH-----AHSANESKPKERPAIPP
KLSKSSPGGSPVSPSAGGPPVSPLADLSDGSSGS------------SGTGPQPAS-----
------------------------------------------------------------
-------------RGPADPVPPCRTNGVT--LSDPSRCPQPVT-----SSALDQRRPRFQ
AGTWSRQCRIEEEEEVEQELLSH----SWGRETKNG---PTDHSNSTTWHRLHPTDGS--
SGQNGKVGTGMSKSASFAFEFPKDRSGIETF-SPPPPPPK--SRHLLKMNKSSSDLEKVS
QGSAESLSPS-FRG-----VHVSFTTGSTDSLASDSRTCSDGGPSSEL-----------A
HSPTNSG---KKLFAP-VPFPSGSTEHVSPSGP-LQPPPLPQKKIVSRAAS-SPDGFFWT
QGSPKPQT---ASPKLNLSHSETN--VHDESHFSYSLSPGNRHHAVFSSSDPLEKAFKG-
SGHWVPAAG--LAGNRGGCGSPGLQCKGTPS--ASSSQLSVSSQASTGST-QFQLHSLLS
NISSKEGTYAKLGGLYTQSLARLVAKCEDLFMGGQKKEL-HFNENNW-SLFKLTCNKPCC
D----SGDAIYYCATCSEDPGSTYAVKICKTPEPKT-VSYC-SPSVPVHFNIQQDCGHFV
ASVPSSMLTCP--DA-PKDPV-PALPAHPPAQEQDCVVVITREVPHQTASDFVRDSAASH
QAEPE

PF00069 // ENSGT00460000041554_1_Domain_1 (1386, 1623)

AYERRVCFLLLQLCNGLEHLKEHGIIHRDLCLENLLLVHCTPQXXXXXXXXXX--
--XXXXXXX----------XXX-----XX-XXXXXPAGGALSPA-----AGPASPEGPRE
KQLPRLIISNFLKAKQKSGG----TPNLQQKKSQARLAPEIVSASQYRKFDEFQTGILIY
ELLHQPNPFEVRAQLRERDYRQEDLPPLPALSLYSP---GLQQLAHLLLEADPIKRIRIG
EAKRVLQCLLWGPRRELVQQPGTSEEALCGTLHNWIDMKRALMMMKFAEKAVDRRRGVEL
EDWLCCQYLASAEPGALLQSLKLLQLL---------

--------------------------------------MSACSDFVEHIWKPGSCKNCFC
LRSDHQLAAGHPQPRT-----GSLPA-PPR--LPPRS----VEDEGV--NGSPYCKPTIA
VKPTMMSSEASDVWTEASLS---AEVPQVIWRRAPSKLPLPK--QEDVPIVYLGSFRGVQ
KPASPSACTD-GSSHCPPAYAMVGLHSLQARGERNMAFHPVGFPDEKAGQ---------E
-LPSAQESFRQKLAAFAE-MTSGCHKGPRPCPSPQPPQ--ESLPSEDESDQRCSPSGDSE
GGEYCSI-LDCCPRTPAAKETIHAEGSQGRCGGGNSSP-MCWERGTSARSPEE-------
-------EKRSLSFPRD--------CCGQGPSA-NPAHLGPKKLSLNSEAA-SSDGLSCG
S-G--SSGTSSPFAPHLENDYCSLMKEA----------VLPGKQQDSDCHVVTSSRCP--
--EFQPPAHPREAAHLEPIYAESTKRKKAVSVPS-RPQAKAKQAPTA--------QGQVW
-TGDGRAQKTKSVWSRDKEGSDTAPQVLATITVMAAHPEEDHRTIYLSSPDSAVGVQWPQ
GPVGQDLE--A------GEEETVA----GQRPSSKESH-----PLDRSENTPKGRPAIPP
KLSKSSPGGSPASPSA-----SSLTDPSEG--TS-G-----------SRAPHSTS-----
------------------------------------------------------------
-------------RGSADPTSSCPTN-------DPARWPPPAA--ST--SALDQRRPRYQ
TGAWSRQCRIEEEEEVEQEM-SQ----SWGREMDNG---TVDHSNSSTWHRFHSTDIS--
SGQNSKIGSGMSKSASFAFEFPKDRSRLEAF-SPPPPPPK--SRHLLKMNKSSSDLEKVS
QGSAESLSPS-FRG-----VHISFTTSSTDSLASDSRTCSDGGQSSEP-----------T
HSPTLGG---KKLFAP-VPFPSGSTENMSPSGP-VQPPPLPQKKIVSRAAS-SPDGVFWT
QGSPKPRT---ASPKLTLSHSETNVSAHDESHFSCSVSPGNRHHPVFS-SEPLEKAFKD-
SGHWVPAPG--LVGSKSSCGSPSLQCKAAPS--TSSSQLSVSSQASSSST-QLQLHSLLS
SISSKEGTYAKLGGLYTQSLARLVAKCEDLFMGGQKKEL-HFNENNW-SLFKLTCNKPCC
D----SGDAIYYCATCSEDPSSTYAVKICKTPEPNT-ASYC-SPSVPVHFNIQQDCGHFV
ASVPSSMLTSP--NT-TKDPL-PVAPSQPPAQEQDCVVVITREVPYQTASDFVCDSAASH
QAEP

PF00069 // ENSGT00460000041554_1_Domain_1 (1385, 1623)

EVYERRVCFLLLQLCNGLEHLKEHGIIHRDLCLENLLLVHCSPQASPGPSHATPAL
S----------------------AATSPC-SPAVPSST-----------------GVPSE
KHLPRLIISNFLKAKQKPGG----TTNLQQKKSQARLAPEIVSASQYRKFDEFQTGILIY
ELLHQPNPFEVRAQLRERDYRREDLPPIPTLSLYSP---GLQQLAHLLLEADPIKRIRIG
EAKRVLQCLLWGPRRELVEPPGPSEEVLSSTLHNWIDMKRALMMMKFAEKAVDRRRGVEL
EDWLCCQYLAAAQPTALLQSLRLLQLL---------

-------------------------MHQTLRLKPESLKMSACSDFVEHIWKPGSCKNCFC
LRSDHQLVAGPPQPRA-----GSLPP-PPR--LPPRPENCRLEDEGV--NSSPYSKPTIA
VKPTMMSSEASDVWTEASLS---AEVSQVIWRRAPGKLPLPK--QEDAPVVYLGSFRGVQ
KPAGPSTSPDSNSPRCPPAYTMVGLHNLEPRSERNVAFHPVSFPDDKAGHKEKPSFPYQD
-RPSTQESFRQKLAAFAG-TTSGSHQGPG------PLR--ESLPSEDDGDQRCSPSGDSE
GGEYCSI-LDCCPGSPVAKAASQAAGSRGRHSGRDGSP-TCWGQGKCAGPTEQ-------
-------EKPGPSFPKE--------CCSQGPTA-HPSCLGPKKASFTSEAAASSDGLACG
SGS--GSGASNPFVPHLESDYCSLMKEP-----------APEKQQDLGCPGVASSRCLGL
TGEPQPPAHPREATQPEPIYAESTKRKKAAPVPS-KPQAKTEHAAAAQGQ----GQGQVW
-TGNAWAQKTASGWGQDS--PDPTPQVAATITVMAAHPEEDHRTIYLSSPDSAVGVQWPP
GPGSQNSEVGE------EE--TLA----RQGLSSRESH-----AHSAKESKPKERPAIPP
KLSKSSPGGSPVSPSAGGPLVSPLADLSDGSSGS------------SGIGPQPPS-----
------------------------------------------------------------
-------------RGPADPVPPCRTNGVT--LSDPSRCPQTVT-----SSALDQRRPRFQ
AGTWSRQCRIEEEEEVEQELLSH----SWGRETKNG---PTDHSNSTTWHRLHPTDGS--
SGQNSKVGTGMSKSASFAFEFPKDRSGIETF-SPPPPPPK--SRHLLKMNKSSSDLEKVS
QGSAESLSPS-FRG-----VHVSFTTGSTDSLASDSRTCSDGGPSSEL-----------A
HSPTNSG---KKLFAP-VPFPSGSTEDVSPRGP-RQPPPLPQKKIVSRAAS-SPDGFFWT
QGSPKPQT---ASPKLNLSHSETN--VHDESHFSSSLSPGNRHHAVFSSSDPLEKAFKG-
SGHWVPAAG--LAGNKGGCGSPGLQCKGTPS--ASSSQLSVSSQASTGST-QFQLHGLLS
NISSKEGTYAKLGGLYTQSLARLVAKCEDLFMGGQKKEL-HFNENNW-SLFKLTCNKPCC
D----SGDAIYYCATCSEDPGSTYAVKICKTPEPKT-VSYC-SPSVPVHFNIQQDCGHFV
ASVPSSMLTSP--DA-PKDPV-PALPAHPPAQEQDC

PF07714 // ENSGT00460000041554_1_Domain_0 (1357, 1423)

VVVITREVPHQTASDFVRDSAASH
QAEPEAYERRVCFLLLQLCNGLEHLKEHGIIHRDLCLENLLLVHCTPQAAPGPTPAT----------------------AAP-----PC-SSAALPAGGTLSPA-----AGPASPEGPREKQLPRLIISNFLKAKQKPGG----TPNLQQKKSQARLAPEIVSASQYRKFDEFQTGILIYELLHQPNPFEVRAQLRERDYRQEDLPPLPALSLYSP---GLQQLAHLLLEADPIKRIRIGEAKRVLQCLLWGPRRELVQQPGTSEEALCGTL

PF00069 // ENSGT00460000041554_1_Domain_1 (1359, 1623)

VITREVPHQTASDFVRDSAASHQAEPEAYERRVCFLLLQLCNGLEHLKEHGIIHRDLCLENLLLVHCTPQAAPGPTPAT---
-------------------AAP-----PC-SSAALPAGGTLSPA-----AGPASPEGPRE
KQLPRLIISNFLKAKQKPGG----TPNLQQKKSQARLAPEIVSASQYRKFDEFQTGILIY
ELLHQPNPFEVRAQLRERDYRQEDLPPLPALSLYSP---GLQQLAHLLLEADPIKRIRIG
EAKRVLQCLLWGPRRELVQQPGTSEEALCGTLHNWIDMKRALMMMKFAEKAVDRRRGVEL
EDWLCCQYLASAEPGALLQSLKLLQLL---------

-------------------------VHQAVRLNLQRPKMSACSDFVEHIWKPGSCKNCFC
LRSDHLLVAGRPQPRA-----GSVPP-PPR--LPPRPENCHLEDEGV--NGVPYSKPTIA
VKPTMMSSEASEVWAEAGVS---SDVSQLIWRRSPSKLPILK--QEEAPRTYLSSFGGGH
KPGGPSNPAD-GSARCPPPYAVVGLHGLETRGERNTALHPLS----KGGREGKPAFPYRE
-LTATHESFRQKLAAFAG-MTSGCSRDPG------PLR--ESLPSEDDSDQRCSPSGDSE
GGEYCSI-LDCCPGSPVARDASQAEDSRRRHAGGVCSP-ACWDQTACAGSPDE-------
-------DMRCPAFLME--------CSALDSVGARPPYLKPSXXXXXXXXXXXXXXXXXX
XXX--XXXXX---XXXXXXXXXXXXXXX-----------XXXXXXXXXXXXXXXXXXXXX
XXXXX----XXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXX------XXXXXX
-XXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXX-----XXXXXXX----XXXXXXXXXX-----XXXXXENTPKGRPAIPP
KLSKSSPAGSPVSPSP-----SPLADLSESSSS-------------SGTGPQPSS-----
------------------------------------------------------------
-------------QGPADFVSSCQTNGVT--ASDTARCLPSTA------LALDQRRPRYQ
TGAWSRQCRIEEEEEVHQEPLGQ----GWGRGVENGSEDTGDPAQASTWHRLHPPDGS--
SGQKSKPSTGMSKSASFAFEFPKDRSGMEAF-SPPPPPPK--SRHLLKMNKSSSDLEKVS
QGSAESLSPS-FRG-----VHVTFTTGSTDSLASDSKTCSDGGPSYEP-----------V
HSPTVGG---KAVLTP-VPFPPGSTEDASPQGP-LQPPPLPQKKIVSRAASFPPDGFFWP
QGSQKPRA---ASPKLKL-HSETSVCVRDGSAFGHPASAGNR-HPVFASSEPLEKSFKG-
NSHWAPAAG--LVGSRSGRGSPGLQGRGTPS--ASGTQLSTPSQASTSNS-QLHLHSLLS
SISSKEGTYAKMGGLFAQSLLRLVAKCEDLFMGGQKKEL-HFNENNW-SLFK

PF00069 // ENSGT00460000041554_1_Domain_1 (1253, 1626)

LTCNKPCC
D----SGDAIYYCATCSKDPGSTYAVKICITPEPKA-ASYC-NPSVPVHFNIQQDCGHFV
ASVPSSMLVSP--DV-PKDSL-PALPSHPPAQEQDCVVVITREVPHQTAADFVRDSASSH
RAEPEVYERRVCFLLLQLCNGLEHLKEHGIIHRDLCLENLLLVHCTPQAGPGPAITPASA
---------------------PAATPSPS-SSAVPSTSVTPS-----ASVASTCRGMPGD
KYLPRLIISNFLKAKQKPGG----TTNLQQKKSQARLAPEIVSASQYRKFDEFQAGILIY
ELLHQPNPFEVRAQLREQDYRQEDLPPLPALSLYSP---GLQQLAHLLLEADPIKRIRIG
EAKRVLQCLLWGPRRELVE-PGCPEEALRGTLQNWIDMKRALMMVKFAEKAVDRRRGVEL
EDWFCCQYLASAEPGAVLQTLKLLALL---------

--------------------------------------MSACSDFVEHIWKPGSCKNCFC
LRSDHQPTAGHPKARA-----NSLPA-GTR--LPARPENCRLDDEGV--NGLAYSKPTIA
VKPTMMTSETSDLWTEASLS---AEVPKVNWRRTPGKLLLPK--QEDEPIVYLGSFRGLQ
KPASPLACTD-GNSRCPPAYTMVGLHNLEARVDRNTAFQPVSFQEEKAGREE--------
-LPSAHESFRQKLAAFAG-MTSSCPKGPRPCTSPQPLR--ESLPSEDDSDQRCSPSGDSE
GGEYCSI-LDCCPESKDAVHSTEG--S--GRRGGDCSP-TCREQGPRTRPTEE-------
-------EKQGLSFPRE--------CCGQGSTA-NPPRLGPKKPSLNSEAASSSDGLSCG
S-S--RSGASSPFAPHLENDYCSLVKEP-----------ASGKQQDLSGHFLTSGKCVGQ
AAELQPASLLRDPVQPEPIYAESAKRKKAAPGPP-RPEPKKEQVPAGH------SQGQVW
-TGDTWIQKTPPSWSQDREGANPAPQVATTITVIAAHPEEDHRTIYLSSPDSAVGVQWPR
GPSNQDLQ---A-----GEEEPLV----AQGLTSRESH-----PHNVTENTAKEKPAIPP
KLSKSSPGGSPVSPA------PPLTDHSDGNTGG------------SSVGPQLLS-----
------------------------------------------------------------
-------------RVPANLTSSCHTNGVAT-AGDSAKCPPPATSS----SVLDQRRPRYQ
TGAWSRQCRIEEEEEVGQEL-SQ----SWGRELENG---TADHSNSSTWHRLHPI-D-GT
SGQNSKTNSGMSKSASFAFEFPKDRGRLEAF-SPPPPPPK--SRHLLKMNKSSSDLEKVS
QSSAESLSPS-FRG-----AHVSFTTGSTDSLASDSRPCSDGGPSYEP-----------T
HSPTISG---KKLFAP-VPFPSGSTEDVSPGGGPAQPPPLPQKKIVSRAAS-SPDGFFWT
QGSPKPRT---ASPKLNLSHSETNVCAHDEPPFNCSLNSGNRSHHVFSSSEPLGKAFKG-
NAPWAPALG--LANSKGGCGSPSLQCRAATS--TSSSQLSVSSQASSSST-QLQLHSLLS
SISSKEGTYAKLGGLYTQSLARLVTKCEDLFMGGQKKEL-RFNENYW-SLFKLTCNKPCC
D----SGDAIYYCATCSEDPGSIYAVKICKTPEPKS-ASYC-SPSVPVHFNIQQDCGHFV
ASVPSSMLAS--PDTSSKDTA-PAVSPQPPAQEQDCVVVITREVPHQTASDFVRDSMASH
RA

PF00069 // ENSGT00460000041554_1_Domain_1 (1383, 1623)

EPEVYERRVCFLLLQLCNGLEHLKEHGIIHRDLCLENLLLAHCNPQSSPGPSATPTVP
T------------------------------------TTSRCP-SAAPAATTACQGGPGE
KQLPRLIISNFLKAKQKPGG----TTNLQQKKSQARLAPEIVSASQYRKFDEFQTGILIY
ELLHQPNPFEVRAQLRERDYRREDLPPLPTLSLYSP---GLQQLAHLLLEADPIKRIRIG
EAKRVLQCLLWGPRRELVEQPCTSEEVLCNTLHNWIDMKRALMMMKFAEKAVDRRRGVEL
EDWLCCQYLASAEPGALLQSLKLLQLL---------

-------------------------MYQAIRLNPESPKMSACSDFVEHIWKPGSCKNCFC
LRSDHQLSPGHHQPRA-----GSLHP-PPR--PSPRPEYCRLEDEGV--NSSPYSKPTIA
VKPTMLSSDASDVWTEANMN---ADVSKVIWRRPPGKLPLPK--QEDLPVVYLGSFRGVQ
KPAGPSASAD-VHPHCPPAYAMVGLHSLEARGEHNTAFHPVSFPDEKAGRENKPVFSYQE
-LNSTQESFRQKLAAFGG-KTSGCHKGPG------PLR--ESLPTEDDSGPRRSPSGDSE
GGEYCSL-LDCRPGSPGTEDTPQAEGPRRRHGGEGR------------SPAEE-------
-------EKRVSSFPRE--------CCSQGLTE-NSSHLGPKQLSLASEAASSSDGLSCG
S-A--SSGTSSPFASHLESDYCSLMKEP-----------VLGKQQDSGCHVVTSSRCLGL
TGEPQPTAHSRESVQPEPIYAESTKRKKAVPAPS-RPQAA-----------A--AQGQVR
-TANTWAQKTTSGWGRDREGPDMGPKVAATITVMAAHPEEDHRTIYLSSPDSAVGVQWPR
RPVSQDSE--A------GDEETSD----GQGMSSREGH-----CHDASEHMSKGRPAIPP
KLSRSSPGGSPVSPSA-----SPLSDVNEG-SSG-G-----------GTGPQPSS-----
------------------------------------------------------------
-------------RGPSDPAPSCRANGVT--DRDSVKCPGPAS--TA--SALDQRRPRYH
TGAWSRQCRIEEEEEVEQDLLSQ----GWGREMENG---TTDPSNSSTWHRLCPTDGS--
SGQNNKAITGMSKSASFAFEFPKDRNGIEAF-SPPPPPPK--SRHLLKMNKSSSDLEKVS
QGSAESLSPS-FRG-----VHVSFTTGSTDSLASDSRTCSDGGPSSEP-----------T
HSPTNSG---KKLFAP-VPFPSGSTEDVSPSGP-VQPPPLPQKKLVSRAAS-SPDGFFWP
QGCPKPRT---ASPKLNLSHSETNVCAREESHFSFSSSPGNRHHHIFSSSEPLEKTFKG-
NGHWVPTSG--LPGSRSGSGSPSLQYRGVPS--ASSSQLSVASQASTSST-QLQLHSLLS
SISSKEGTYTKLVGLYAQSLVRLVAKCEDLFMGGQKKEL-HFNENNW-SLFKLTCNKPCC
D----SGDAIYYCATCSEDPGSTYAVKICKTPEPKT-ASYC-SPSVPVHFNIQQDCGHFV
ASVPSSMLTSP--DT-PKDPL-PALPSHPPAQEQDCVVVITREVPHQTASDFVRDSATSH
QSEPEVYERRVCFLL

PF07714 // ENSGT00460000041554_1_Domain_2 (1396, 1422)

LQLCNGLEHLKEHRVIHRDLCLENLLLVHCTPQATPSPSPAT---
----------------STTPVAAATPCPC-PSATLPVGATPS-----APAAPACQRVPSE
KHLPRLIISNFLKAKQKPGG----TTNLQQKKNQARLAPEIVSASQYSKFDEFQTGILIY
ELLHQPNPFEVRAQLREKDYRQEDLPPLPTLSLYSP---GLQQLAHLLLEADPIKRIRIG
EAKRVLQCLLWGPRRELVEQRGTSEEALCSTLHNWIDMKRALMMMKFAEKAVDRRRGVEL
EDWLCCQYLASAEPGALLQSLKLLQLL---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------MASGCAKDPGPCSSSQALR--ESLPSEDDSDQRCSPSGDSE
GGEYCSI-LDCCPGSPVAKDASQAESSRLRHGGGDCSP-ACWDQAVCAGSAEE-------
-------DKRVPGFLRE--------CHAQDPAE-PPSRLGPKKPSLTSEAASSSDGISCG
S-G--SSGTSSPFAPHLESDYCSLIKEP-----------VLEKPQEAGCHVVNSSRCLGL
SGEVQPPDPSREALQPEPIYAESTKRKKAGPAPP-RPQAKAGQAAPAQ------GQGQGR
-TGNTWAQKTACVWGRDREGPDVGTQVTATITVMAAHPEEDHRTIYLSSPDSAVGLQWPR
GPASQDSE---A-----GEEETST----GQGLSSRDSH-----SHDVGENTPKGRPAIPP
KLSKSSPCGSPVSPSA-----SPLPDLSEGSS---G----------SGVGPQPSS-----
------------------------------------------------------------
-------------RGPADPAPSCRTNGVT--ANDTVRCPPPPSTSTSATVPSDQRRPRYQ
IGAWSRQCRIEEEEEVEQELLGP----GWGREMENG---TTDASHSSTWHRLHPTDGP--
SSQNSKAGTGMSKSASFAFEFPKDRSGIEVF-SPPPPPPK--SRHLLKMNKSSSDLEKVS
QGSAESLSPS-FRG-----VHVSFTTGSTDSLASDSRTCSDGGPPYEP-----------A
QSPTNSG---KKLFAP-VPFPSGSTEDVSPSSP-LQPPPLPQKKLVSRAAS-SPDGFFWT
QGSSKPRA---ASPKLNLSHSETSVCVHDESPFSYALSTGNRHHHVFSSSEPLEKTFKG-
NGHWAPAAG--LAGSKSGRRSPSLQGKGAPS--ASASQLSVSSQASTASS-QRQLPSLLS
SISSKEGTYAKMAGLFAQSLLRLVAKCEDLFMGGQKKEL-HFNENNW-SLFK

PF00069 // ENSGT00460000041554_1_Domain_1 (1253, 1629)

LTCNKPCC
D----SGDAIYYCATCSEDPGSTYAVKICKTPEPKA-ASYC-SPSVPVHFNIQQDCGHFV
ASVPSSMLTSP--DA-PKDPP-PALPPHPPAQEQDCVVVITREVPHQTAADFVRDSATSH
RAEPEAYERRVCFLLLQLCNGLEHLKEHGVIHRDLCLENLLLVHCTPQASQPAT------
----------------------PGTPSTC-SSTTLSTSVTPS-----LPAAATCRGVPGG
KHLPRLIISNFLKAKQKPGG----TGNLQQKKSQARLAPEIVSASQYRKFDEFQAGILIY
ELLHQPNPFEVRAQLREQDYRQEDLPPLPALSLYSP---GLQQLAHLLLEANPIKRIRIS
EATRVLQCLLWGPRRELVEQPGSPEEALCGILQNWIDMKRALMMMKFAEKAVDRRRGVEL
EDWLCCQYLASAEPRALLQTLKLLQLL---------

-------------------------MQQSIRLNPEPLKMSACSDFVEHIWKPGSCKNCFC
LRSDHQLAAGRPQPRA-----GSLP---------PRPDNGRLEDDGV--SSSPYSKPTIA
VKPTMMSSEAPDVWTEAGVS---TEVSQVIWRRAPGKLPLPK--QEDVPVVYLGSFRGVP
KPVGPCASAE-GGPRCPPAYAVVGLHSLETRGDRSPAFHPVSFPDDKVGREEKA-----E
-LPSAQESFRQKLAAFAG-LS----------------R--GSLPSEDDSDQRCSPSGDSE
GGEYCSI-LDCCPGSPAAQGA--------LPAGGDCSP-PRWEPTAA-----E-------
-------ERRAL-------------SGSPGPAA-YPPRLGPKKPSLTSEAASSSDGLSCC
S-R--SSGTSSPFAPHLDSDYCSLVKDP----------APAKHQDSGGCH-VTPSRCLGP
AGEPQ----PREAVLPEPIYAESTKRKKAPPGPP-RSQAKAEQTAAA--------QGQVW
-TSEARAHKVAAGWSQDREGSDMAPQVGATITVMATHPEEDHRTIYLSSPDSAVGVQWPR
GHGSQDSD--V------GQDETSA----RQCLSSREGH-----AHDTSESGLKGRPAIPP
KLSKSSPGGSPVSSSP-----SPLADLGEG-----------------SLGPAPVS-----
------------------------------------------------------------
-------------RGPAEPTPSCRTNGAA--ASDPVRCPPPAA--TP--SAVDQRRPRYQ
PGAWSRQCRIEEEEEAEQELLSH----SWGRETENG---PMAPSSASTWHRVHPTDGSSS
SGQHGKASTGMSKSASFAFEFPKDRSRMETF-SPPPPPPK--SRHLLKMNKSSSDLEKVS
QGSAESLSPS-FRG-----VQVSFTTGSTDSLASDSRTASDGGTPWVM-----------S
HLCTG-----Y-RWLS-VSVHSGSEQQSFPDSY-HLPFPIPLCKKSHETDY-PRK--GWP
SAPSVPGL-VSVPGTMGLRHRPH-PGVGEERHSG---CPGRKYWERLLEEKETNEGPES-
AFHWKCASTFRLQGQASGLALPGRRSKATGH--VSGTPFRLSPCVSQGYR-NCNLCKLFG
NL---SGLVVKVSDLKFKTKKRSFKFCRNDILEILNREV-DTRGRRWVRLFKILALIPVC
FPAGIPSDSLLHHSACPHNPGSPADLTICKTPEPKA-ASYC-SPSVPVHFNIQQDCGHFV
ASVPSSMLAPP--DA-PKDPQ-PALPAQPPAQEQDC

PF07714 // ENSGT00460000041554_1_Domain_1 (1357, 1570)

VVVITREVPHQTASDFVRDSAASH
RAEPEAYERRVCFLLLQLCNGLEHLKEHGVIHRDLCLENLLLVRC---------------
--------------------------------------------------APQCQGVPGD
KQLPRLIISNFLKAKQKPGG----STNLQQKKSQARLAPEIVSASQYRKFDEFQTGILIY
ELLHQPNPFEVRAQLREQDYRQEDLPPLPALSLYSP---GLQQLAHLLLEADPIKRIRIG
EAKRVLQCLLWGPRRELVEQPGPSEEALCSTLHNWIDMKRALMMMKFAEKAVDRRRGVEL
EDWLCCQYLASAEPRAVLQSLKLLQLL---------

-------------------------MHQTLRLKPESLKMSACSDFVEHIWKPGSCKNCFC
LRSDHQLVAGPPQPRA-----GSLPP-PPR--LPPRPENCRLEDEGV--NSSPYSKPTIA
VKPTMMSSEASDVWTEAGLS---AEVSQVIWRRAPGKLPLPK--QEDAPVVYLGSFRGVQ
KPAGPSTSPDGNSPRCPPAYTMVGLHNLEPRGERNVAFHPVSFPDDKAGHKEKPSFPYQD
-RPSTQGSFRQKLAAFAG-TTSGCHQGPG------PLR--ESLPSEDDGDQRCSPSGDSE
GGEYCSI-LDCCPGSPVAKAASQAAGSRGRHSGRDGSP-TCWEQGKCAGPTEQ-------
-------EKRGLSFPKE--------CCSQGPTA-HPSCLGPKKASFTSEAATSSDGLACG
SGS--GSGASNPFLPHLESDYCSLMKEP-----------TPEKQQDLGCPGVASSRCLGL
TGEPQPPAHPREATQPEPIYAESTKRKKAAPLPS-KPQAKTEHAAAAQGQGQGQGQGQVW
-TGNAWAQKTASGWGQDS--PDPTPQVAATITVMAAHPEEDHRTIYLSSPDSAVGVQWPP
GPGSQNSEVGE------EE--TLA----RQGLSSRESH-----AHSAKESKPKERPAIPP
KLSKSSPGGSPVSPSAGGPPVSPLADLSDGSSGS------------SGIGPQPPS-----
------------------------------------------------------------
-------------RGPADPIPPCRTNGVT--LSDPSRCPQPVT------SALDQRRPRFQ
AGTWSRQCRIEEEEEVEQELLSH----SWGRETKNG---PTDHSNSTTWHRLHPTDGS--
SGQNSKVGTGMSKSASFAFEFPKDRSGIETF-SPPPPPPK--SRHLLKMNKSSSDLEKVS
QGSAESLSPS-FRG-----VHVSFTTGSTDSLASDSRTCSDGGPSSEL-----------A
HSPTNSG---KKLFAP-VPFPSGSTEDVSPSGP-RQPPPLPQKKIVSRAAS-SPDGFFWT
QGSPKPQT---ASPKLNLSHSETN--VHDESHFSSSLSPGNRHHAVFSSSDPLEKAFKG-
SGHWVPAAG--LAGSTGGCGSPGLQCKGTPS--ASSSQLSVSSQASTGST-QFQLHGLLS
NISSKEGTYAKLGGLYTQSLARLVAKCEDLFMGGQKKEL-HFNENNW-SLFKLTCNKPCC
D----SGDAIYYCATCSEDPGSTYAVKICKTPEPKT-VSYC-SPSVPVHFNIQQDCGHFV
ASVPSSMLTSP--DA-PKDPV-PTLPAHPPAQEQDCVVVITREVPHQTASDFVRDSVASH
QAEPE

PF00069 // ENSGT00460000041554_1_Domain_1 (1386, 1623)

AYERRVCFLLLQLCNGLEHLKEHGIIHRDLCLENLLLVHCTPQAAPGPTPAT---
-------------------AAP-----PC-SSAALPAGGTLSPA-----AGPASPEGPRE
KQLPRLIISNFLKAKQKPGG----TPNLQQKKSQARLAPEIVSASQYRKFDEFQTGILIY
ELLHQPNPFEVRAQLRERDYRQEDLPPLPALSLYSP---GLQQLAHLLLEADPIKRIRIG
EAKRVLQCLLWGPRRELVQQPGTSEEALCGTLHNWIDMKRALMMMKFAEKAVDRRRGVEL
EDWLCCQYLASAEPGAVLQSLKLLQLL---------

-------------------------MHQTLQLNPESPKMSACSDFVEHIWKPGSCKNCFC
LRSDHQLVASHPQPRA-----GSLPP-PLR--LPPRPEHCRLEDEGV--NSSPYSKPTIA
VKPTMMSSEASDVWTEANLS---AEVSQVIWRQAPGKLPLPK--QED---VYLGSFRSAQ
KSAGPSAAAN-GNARCPPAYAMVGLHSLEARGERSVAFHPVSFPEDKGRREDKPSVPYPD
-LPSAQESFRQRLAAFAG-TTSGCHKGAS----PQPLR--ESLPSEDDSDQRCSPSGDSE
GGEYCSI-LDCCPGSPVAKDACQAEGHRGRRGGGDCSP-TCWEQGTCARPAED-------
-------KKRVLSFPRD--------FCSQGQPA-NPPCLGPKKPSLSLEAATSSDGLSCG
S-S--SSRASSPCPPHLESDYCSLMKEP-----------APGKQQDPGCHGATSSRRLGL
AGDAPPPAHPREAAQPEPIYAESTKRKKAVPAPS-RPQAKAEQASAAQGQGQ--GQVRT-
-GNSVWSQKTAPGWGRDS--PDPAPQVAATITVMAAHPEEDHRTIYLSSPDSAVGVQWPR
GPVSQDSE---V-----GQEETSA----RQGRSSRESR-----SHDASRNTPKGRPAIPP
KLSKSSPGGSPVSPSA-----SPLADLSEGSSGGGG----------GGIGPPPAS-----
------------------------------------------------------------
-------------RGPTDPASSCRANS------DPARCPLPAAASSS--STLDQRRPRFQ
TGTWSRQCRIEEEEEVEQELLSQ----SWGRELKNG---TMDHSHSTTWHRLHTTDGS--
SGQNSKVGTGMSKSASFAFEFPKDRSGIETF-SPPPPPPK--SRHLLKMNKSSSDLEKVS
QGSAESLSPS-FRG-----AHVSFTTGSTDSLASDSRTCSDGGPSYEA-----------A
HSPTISG---KKLFAP-MPFPSGSTEDVSPSGS-LQPPPLPQKKIVSRAAS-SPDGFFWT
QGSPKPRT---ASPKLNLSHSETN--VHDESHFSYSLNPGNRHRHGFSSSEPLERAFKG-
NGPWVPVPG--PAGNRSGGGSPGPQCRGAAS--ASSSQLSVSSQASSGSA-QLQLHSLLS
SISSKEGTYAKLGGLYTQSLARLVAKCEDLFMGGQKKEL-HFNENNW-SLFKLTCNKPCC
D----SGDAIYYCATCSEDPGSAYAVKICKTPEPKT-ASYC-SPSVPVHFNIQQDCGHFV
ASVPSSMLNSP--DA-PKDPA-PAPPSQPPAQEQDCVVVITREVPHQTASDFVRDSAASH
QAEPE

PF00069 // ENSGT00460000041554_1_Domain_1 (1386, 1623)

AYERRVCFLLLQLCNGLEHLKEHGIIHRDLCLENLLLVHCAPPAAPATNAPPAP-
-----------------------APAAQG-PSAAVPAGA-----------------VPGE
KQLPRLIISNFLKAKQKPGG----TPNLQQQKSQARLAPEIVSASQYRKFDEFQTGILIY
ELLHQPNPFEVRARLRERDYRQEDLPPLPALSLYSP---GLQQLAHLLLEADPIKRIRIG
EAKRVLQCLLWGPRRELVEPPAASEEALCGTLHNWIDVKRALVMMKFAEKAVDRRRGVEL
EDWLCCQYLASAEPGALLQSLKLLQLL---------

-------------------------MLETIPLNPESPKMSACSDFVEHIWKPGSCKNCFC
LRSDHQLVPGRPQPRV-----GCLPP-PPR--LHPRPESDRPEDDGL--SGSPYSKPTIA
VKPTMMSSEASDGWTEAGMS---ADVAQVIWRRAPGKLPLPK--QEDGPVVYLGSFRGVQ
KPAGPSGPTDGGHPRSPPAYAMVGLHSLEPRGDRSAAFHPVSFPDEKLGRDDKPVIPYQE
-LNSPQESFRQKLAAFSG-MTSGCLKGLGPYPSAQPMR--ESLPSEDDSDQRCSPSGDSE
GGEYCSI-LDCCPGSPGAEDAARAGGSRHRQGGRDCSA-ACWEPRVCARPPEE-------
-------EKQALSFPRD--------CCSQGPTE-SPPRLGPKKQSLASEAASSSDGLSCG
S-A--NSRASSPLAPHPESDYCSLRKEP-----------GLGKQQDSGCHGVASSRRLGQ
TGETQPPAHSREAAQSEPIYAESTKRKKAVPVPS-RPQAKAEQGAGAP------GQAQVR
-TVNTWAQKAASGWGQVREGPDAAPQMAATITVMAAHPEEDHRTIYLSSPDSSVGVQWPR
GPPSQQAP--EA-----GGEEPSA----GQGLGSRESR-----HRSASETTAKGRPAIPP
KMSRSSPGGSPVSPSA-----YPLSDLSEGNSG--------------TPGPQPPS-----
------------------------------------------------------------
-------------KGPADPASSCRANGIP--SSDSARGPPPATST----SALEQRRPRPQ
AGAWSRQCRIEEEDEVEQDLLSQ----SWGREVENG---PLDPASSSAWHRLRPTDGS--
SGQNSKAGTGMSKSASFAFEFPKDRSGIETF-SPPPPPPK--SRHLLKMNKSSSDLEKVS
QGSAESLSPS-FRG-----VHVSFTTGSTDSLASDSRTCSDGGPSSEP-----------A
HSPTNSR---KKLFAP-VPFPSGSTEDVSPGDP-LQPPPLPQKKLVSRAAS-SPDGFFWT
QGSPKPRT---ASPKLNLSHSETNVCAHEDSHFSYASGPGGRHQHVFSASEPLEKTSKG-
SGHRGPVLG--LG------GSKGLQGKGVSS--ASSSQLSVSSQASAGST-QLQLHSLLN
SISSKEGTYAKLGGLYAQSLVRLVARCEDLFMGGQKKEL-HFSENNW-SLFKLTCNKPCC
D----SGDAIYYCATCSEDPGSTYAVKICKTPEPKA-ASYC-SPSVPVHFNIQQDCGHFV
ASVPSSMLTSP--DA-HKDPL-SALPSHPPAQEQDCVV

PF07714 // ENSGT00460000041554_1_Domain_0 (1359, 1423)

VITREVPHQTASDFVRDLAASH
QSEPEVYERRVCFLLLQLCNGLEHLKEHGIIHRDLCLENLLLVHCAPQASPEPSTAASLPPTT--------------TSPAPAATPSSG-PSATVPTSVNPT-----PPAAPAFQGGSSEKHLPRLIISNFLKAKQKPGG----TTNLQQKKSQARLAPEIVSASQYRKFDEFQTGILIYELLHQPNPFEVRAQLREQDYRQEDLPPLPALSLYSP---GLQRLAHLLLEADPIKRIRIGEAKRVLQCLLWGPRRELVEPPGASEEVLCTTLH

PF00069 // ENSGT00460000041554_1_Domain_1 (1360, 1623)

ITREVPHQTASDFVRDLAASHQSEPEVYERRVCFLLLQLCNGLEHLKEHGIIHRDLCLENLLLVHCAPQASPEPSTAASLP
PTT--------------TSPAPAATPSSG-PSATVPTSVNPT-----PPAAPAFQGGSSE
KHLPRLIISNFLKAKQKPGG----TTNLQQKKSQARLAPEIVSASQYRKFDEFQTGILIY
ELLHQPNPFEVRAQLREQDYRQEDLPPLPALSLYSP---GLQRLAHLLLEADPIKRIRIG
EAKRVLQCLLWGPRRELVEPPGASEEVLCTTLHNWIDMKRALMMMKFAEKAVDRRRGVEL
EDWLCCQYLASAEPTALLQSLKLLQLL---------

-------------------------MHQTLRLKPESLKMSACSDFVEHIWKPGSCKNCFC
LRSDHQLVAGPPQPRV-----GSLPP-PPR--LPPRPENCRLEDEGV--NSSPYSKPTIA
VKPTMMSSEASDVWTEASLS---AEVSQVIWRRAPGKLPLPK--QEDAPVVYLGSFRGVQ
KPAGPSTSPDGNSPRCPPAYTMVGLHNLEPRGERNIAFHPVSFPDEKAGHKEKPSFPYQD
-RPSTQGSFRQKLAAFAG-TTSGCHQGPG------PLR--ESLPSEDDGDQRCSPSGDSE
GGEYCSI-LDCCPGSPVAKAASQAAGSRGRHSGRDGSP-TCWEQGKCAGPTEQ-------
-------EKRGPSFPKE--------CCSQGPTA-HPSCLGPKKASFTSEAATSSDGLACG
SGS--GSGASNPFVPHLESDYCSLMKEP-----------APEKQQDLGCPGVASSRCLGL
TGEPQPPAHPREATQPEPIYAESTKRKKAAPVPS-KPQAKTEHAAAAQGQGQGQGQGQVW
-TGNAWAQKTASGWGQDS--PDPTPQVAATITVMAAHPEEDHRTIYLSSPDSAVGVQWPR
GPVSQNSEVGE------EE--TLA----RQGLSSRESH-----AHSAKESKPKERPAIPP
KLSKSSPGGSPVSPSAGGPPVSPLADLSDGSSGS------------SGIGPQPPS-----
------------------------------------------------------------
-------------RGPADPVPPCRTNGVT--LSDPSRCPQPVT------SALDQRRPRFQ
AGTWSRQCRIEEEEEVEQELLSH----SWGRETKNG---PTDHSNSTTWHRLHPTDGS--
SGQNSKVGTGMSKSASFAFEFPKDRSGIETF-SPPPPPPK--SRHLLKMNKSSSDLEKVS
QGSAESLSPS-FRG-----VHVSFTTGSTDSLASDSRTCSDGGPSSEL-----------A
HSPTNSG---KKLFAP-VPFPSGSTEDVSPSGP-RQPPPLPQKKIVSRAAS-SPDGFFWT
QGSPKPQT---ASPKLNLSHSETN--VHDESHFSSSLSPGNRHHAVFSSSDPLEKAFKG-
SGHWVPAAG--LAGNRGGCGSPGLQCKGTPS--ASSSQLSVSSQASTGST-QFQLHGLLS
NISSKEGTYAKLGGLYTQSLARLVAKCEDLFIGGQKKEL-HFNENNW-SLFKLTCNKPCC
D----SGDAIYYCATCSEDPGSTYAVKICKTPEPKT-VSYC-SPSVPVHFNIQQDCGHFV
ASVPSSMLTSP--DA-PKDPV-PTLSAQPPAQEQDCVVVITREVPHQTASDFVRDSAASH
QAEPE

PF00069 // ENSGT00460000041554_1_Domain_1 (1386, 1623)

AYERRVCFLLLQLCNGLEHLKEHGIIHRDLCLENLLLVHCTPQAAPGPTPAT---
-------------------AAP-----PC-SSAALPAGGTLSPA-----AGPASPEGPRE
KQLPRLIISNFLKAKQKPGG----TPNLQQKKSQARLAPEIVSASQYRKFDEFQTGILIY
ELLHQPNPFEVRAQLRERDYRQEDLPPLPALSLYSP---GLQQLAHLLLEADPIKRIRIG
EAKRVLQCLLWGPRRELVQQPGTSEEALCGTLHNWIDMKRALMMMKFAEKAVDRRRGVEL
EDWLCCQYLASAEPGALLQSLKLLQLL---------

--------------------------------------MSACSDFVEHVWKPGSCKNCFC
LRSDHQLTTGHPKARA-----SSLPA-VTR--LPARPENCRLEDDGV--NGFSYSKPTIA
VKPTMMSSETSDLWAEASLS---AEVPKVSWRRAPGKLPFQK--QEDGPIVYLGSFRGMQ
KPSGTLACTD-GNS-CPPAYTMVGLHNLDARVDRSTAFQPVSFQEEKAGRED--------
-LPSAQQSFRQKLAAFAG-MTSSCSKGPRPCPSPQPPR--ESLPSEDDSDQRCSPSGDSE
GGEYCSI-LDCCPESKDAVHNPEG--S--GRRGGDLSP-MCWEQGTCTRPTEE-------
-------EKRLLDFPRE--------CCGQGSTT-NPPRLGPKKLSLNSEAASSSDGLSCG
S-G--SSGASSPFAPHLENDHCSLVKEP-----------AAGKQQDSGCHGITSGKCVGQ
VGELQPPALPREAVQPEPIYAESTKRKKAVPVPS-RPETKAEQVAAGH------SQGQVW
-TGDTWAQKT--------SGTNMPPQVATTITVIAAHPEEDHRTIYLSSPDSAVGVQWPN
GPSSQDAQ---A-----GEEEPLA----MQGLSSRESH-----PHNVTENTPKEKPAIPP
KLSKSSPGGSPASPAA-----SPLTDHSDGNVGG------------SCAGPQPLS-----
------------------------------------------------------------
-------------RVPTNRTSSCQTNGVAAAAGDPAKCPPPATSS----SALDQRRPRYQ
TGAWSRQCRIEEENEVGQELLSQ----SWGREVENG---TTDHSNSSTWHRFHPTTD-GS
SGQNSKASSGMSKSASFAFEFPKDRGRMEAF-SPPPPPPK--SRHLLKMNKSSSDLEKVS
QSSAESLSPS-FRG-----AHVSFTTGSTDSLASDSRTCSDGGPSYEP-----------A
HSPTISG---KKLFAP-VPFPSGSTEDVSPS-GPAQPPPLPQKKIVSRAAS-SPDGFFWT
QGSPKPRT---ASPKLNVSHSETNVCVHDELLFSYSLNSGDAAHHVFSSSEPLEKAFKG-
SGPWGPALG--LAGSKGGCGSPGLQCRTAASASASSSQLSVSSQASSSST-QLQLHSLLS
SISSKEGTYAKLGGLYTQSLARLVTKCEDLFMGGQKKEL-RFNENNW-SLFKLTCNKPCC
D----SGDAIYYCATCSEDPGSTYAVKICKTPEPKS-ASYC-SPSVPVHFNIQQDCGHFV
ASVPSSMLASP--DTSSKDPA-PAAASHSPSQEQDCVVVITREVPHQTASDFVRDSTASH
RA

PF00069 // ENSGT00460000041554_1_Domain_1 (1383, 1623)

EPEVYERRVCFLLLQLCNGLEHLKEHGIIHRDLCLENLLLAHCSPQGSPGPSATPTT-
-----TTT----------------------------TTTPRCP-SATPTATAACQGGPGE
KHLPRLIISNFLKAKQKPGG----TTNLQQKKSQARLAPEIVSASQYRKFDEFQTGILIY
ELLHQPNPFEVRAQLRERDYRREDLPPLPTLSLYSP---GLQQLAHLLLEADPIKRIRIG
EAKRVLQCLLWGPRRELVEQPCSSEEVLCNTLNNWIDMKRALMMMKFAEKAVDRRRGVEL
EDWLCCQYLASAEPGALLQSLKLLQLL---------

-------------------------MHQTLRLNPESPKMSACSDFVEHIWKPGSCKNCFC
LRSDHQLVAGPPQPRA-----GSLPP-PPR--QPPRPESGRLEDEGV--NSSPYSKPTIA
VKPTMMSSEASDVWTEASLS---AEVSQVIWRRAPGKVPLSK--QEDAHVVYLGSFRSVQ
KPAGPSASPDGNA-CCPPAYTMVGLHNLEPHGEKNVAFHPVSFPDEKVGHKEKPSFSYQD
-RPPAQESFRQKLAAFSG-TTSSCHQSPG------PLR--ESLPSEDDSDQRCSPSGDSE
GGEYCSI-LDCCPGSPVAKAASQAAGSRGRHGDRDCSP-TCWERGKCAGPSEQ-------
-------EKQGLSLPRE--------CCSQGPTA-HSSRLGPKKPSLTSETANSSDGLSCG
SS----SGASSPFIPHLESEYCSLMKEP-----------APGKQQDPGCLGVASSRCLGP
MGESQPPAHPREATQPEPIYAESTKRKKPTPVTS-KPQAKKELAAAAQGQGQGQGQGQVW
-TGNAWAQKTASGWGQDS--PDPAPQVAATITVMAAHPEEDHRTIYLSSPDSAVGVQWPR
GPVSQDSEVGE------EE--TSA----GPGLNSRESH-----AHSTSESKPKGRPAIPP
KLSKNSPGGSPVSPS-----ASPLADLSDGSPSG------------SGIGPQPPS-----
------------------------------------------------------------
-------------RGPAEPAPPCRTNGVT--ISDPSRCPHPAA-----SSALEQRRPRFQ
AGTWSRQCRIEEEEEVEQELLSH----SWGRETKNG---PTDRSNTTTWHRFCPTDGS--
SVQNSKVGTGMSKSASFAFEFPKDRSGIETF-SPPPPPPK--SRHLLKMNKSSSDLEKVS
QGSAESLSPS-FRG-----VHVSFTTGSTDSLASDSRTCSDGGPSAEL-----------A
HSPTNSG---KKLFAP-VPFPSGSTEDVSSSGP-LQPPPLPQKKIVSRAAS-SPDGFFWT
QGSPKPRT---ASPKLNLSHSETN--VHDESHFSYSLSSGNRHHPVFSSSEPLEKAFKG-
NGHWVPAAG--LLGSRSGRGSPGLQCKGAPS--ASSSQLSVSSQASTGST-QLQLHGLLS
SISSKEGTYAKLGGLYTQSLARLVAKCEDLFMGGQKKEL-HFNENNW-SLFKLTCNKPCC
D----SGDAIYYCATCSEDPGSTYAVKICKTPEPKT-VSYC-SPSVPVHFNIQQDCGHFV
ASVPSSMLTSH--DA-PKDPV-PALPSHPPAQEQDCVVVITREVPHQTASDFVRHSAASH
QAEPE

PF00069 // ENSGT00460000041554_1_Domain_1 (1386, 1623)

AYERRVCFLLLQLCNGLEHLKEHGIIHRDLCLENLLLVHCTPPAAPAPAAAPP--
-------PA----------AAP-----PC-SSGALPASGSPSPA-----AGPACPGRPGE
KQLPRLIISNFLKAKQKPGG----TPNLQQKKSQARLAPEIVSASQYRKFDEFQTGILIY
ELLHQPNPFEVRAQLRERDYRQEDLPPLPALSLYSP---GLQQLAHLLLEADPIKRIRIG
EAKRVLQCLLWGPRRELVQQPGTSEEALCGTLHNWIDMKRALMMMKFAEKAVDRRRGVEL
EDWLCCQYLASAEPGALLQSLKLLQLL---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------TITVMAAHPEEDHRTIYLSSPDSAVGVQWPQ
GPVCQDIE---A-----GEDETPA----VSY--RESQH-----PHGAGNSTPRRKPAIPP
KLSRSSPGGSPVSPSA-----SPLADLSDGSPGS------------GSLGLAPAC-----
------------------------------------------------------------
-------------KGPADPTPACRTNGVA--ASNSVRQHAP--------SAVDPRRPRFQ
TGAWSRQCRIEEEEEAGHELLSH----SWGRELN-------GPSSSSTWHRVQPPDAA--
SGPHGKASTGMSKSASFAFEFPMDRSEMETF-SPPPPPPK--ARHLLKMNKSSSDLEKVS
QGSAESLSPS-FRG-----VHVSFTTGSTDSLASDSRTGSDGGPSSEP-----------T
HSPTISG---KKLFAP-VPFPSGSTEDMFPSGP-AQPPPLPQKKIVSRAAS-SPDGFFWT
QGSPKPRT---TSPKLNLSHSDTNVCVQDEPHLSSSLNSGGHHHHVFSSSEPLEKAFRG-
TGHWAPAS---LAGSHSRCGSPGPQGKGLPC--ASSSQLSVSSQASSNST-QLQLHSLLS
SISSKEGTYAKLGGLYTQSLARLVSKCEDLFMGGQKNEL-HFNENNW-SLFKLTCNKPCC
D----SGDAIYYCATCSEDPGSTYAVKICKTPEPKA-ASYC-SPSVPVHFNIQQDCGHFV
ASVPSSMLAPP--EA-PKDPP-PALTAQPPAQEQDCVVVITREVPHQTASDFVRDSAASH
RAEPEAYERRVCFLL

PF07714 // ENSGT00460000041554_1_Domain_2 (1396, 1422)

LQLCNGLEHLKEHGVIHRDLCLENLLLVRCMPQATPTPNPAPALA
PTTATT-------------PGP-AAPSSA-STSAAGAGATPS-----PAATPACQGAPGD
KQLPRLIISNFLKAKQKPGG----STNLQQKKNQARLAPEIVSASQYRKFDEFQTGILIY
ELLHQPNPFEVRAQLREQDYRQEDLPPLPALSLYSP---GLQQLAHLLLEADPIKRIRIG
EAKRVLQCLLWGPRRELVEQPGPSEEALCSTLHNWIDMKRALMMMKFAEKAVDRRRGVEL
EDWLCCQYLASAEPRALLQSLKLLQLL---------

--------------------------------------MSACSDFVEHIWKPGSCKNCFC
LRSDHQLAAGCPQPRA-----GSLPP-PPR--LPPRPENCRLEDEGV--NSSPYSKPTIA
VKPTMMSSETSDVWTEANLS---ADVQQALWRRAPGKLPLPK--QESMPIVYLGSFRGIQ
KPAAPPACAD-GGPRCPPAYAMVGLHNLEARGERNIAIHPGSFPDEKPGREEKPPFPYPE
-LPTAQESFRQKLAAFAG-MTSGCPKSPRPCPSPQPLR--ESLPSEDDSDQRCSPSGDSE
GGEYCSI-VDCCPGSPVAKDAALAEGSRGRPGAGTCSP-TCWEQGTCAGPKDE-------
-------EKRVLSFPSE--------CCGQGPTA-NRPHLGPKKLSLASDAASSSDGLSCG
S-T--HSGASSPFAAHLESDYCSLVKEP-----------ESGKQQDSGCHLATSSRCPGL
AAEPQAPPHPREAVQPEPIYAESTKRKKPVPVPS-RPQAKAEQA-------A--GQGQVW
-TGDVWTQKTVSGWSQDREGSDRTPQVSATITVMAAHPEEDHRTIYLSSPDSAVGVQWPR
GPVSQNSE--A------GEEQTPD----GQGPSSSESH-----PHDATESTPKARPAIPP
KLSKSSPGASPS---S-----SPLADPGEGGSSG-S-----------GLGPQPSS-----
------------------------------------------------------------
-------------QGPTDPASSCRINGIV--SNEPARCLPPAT---S--SALDQRRPRFQ
TGAWSRQCRIEEEEEVEQELLSQ----SWGRETENG---IMDHSNSSTWHRLHSMDGS--
SGQNSKAGTGMSKSASFAFEFPKDRSRMEAF-SPPPPPPK--SRHLLKMNKSSSDLEKVS
QSSAESLSPS-FRG-----VPISFTTGSTDSLASDSRTCSDGGPPYEP-----------T
HSPTISG---KKLFAP-VPFPSGSTEDVTHSGP-AQPPPLPQKKLVSRAAS-SPDGFFWT
QGSPRTRT---TSPKLNLSHSETNVCVHDETHFSYSLSPGNRHHHVFSSSEPLEKAFKG-
NGHWVPVPG--LAGGKGSCGSPSLQCKAATS--TSSSQLSVCSQASSSST-QLQLHSLLS
SISSKEGTYAKLGGLYTQSLARLVAKCEDLFMGGQKKEL-HFNENNW-SLFKLTCNKPCC
D----SGDAIYYCATCSEDPGSTYAVKICKTPEPKT-ASYC-SPSVPVHFNIQQDCGHFV
ASVPSSMLTSP--DA-PKDSL-PAPPLQPPAQEQDCVVVITREVPHQTASDFVRDSAASH
RAEPE

PF00069 // ENSGT00460000041554_1_Domain_1 (1386, 1623)

AYERRVCFLLLQLCNGLEHLKEHRIIHRDLCLENLLLVHCSPQASPGPSPNVPAP
PTTT------------------------------------SP-----SPSASQASGVPSE
KQLPRLIISNFLKAKQKPGS----TTNLQQKKSQARLAPEIVSASQYSKFDEFQTGILIY
ELLHQPNPFEVRTQLREQDYRREDLPPLPTLSLYSP---GLQQLAHLLLEADPIKRIRIG
EAKRVLQCLLWGPRRELVEQPGTSEEVLCSTLHNWIDMKRALMMMKFAEKAVDRRRGVEL
EDWLCCQYLASAEPGALLQSLKLLQLL---------