Query Results 

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-------------MDSEIGCLIRFY--AGKPHSTGSSERIQLSGMYNVRKGKM

PF00169 // ENSGT00440000037833_1_Domain_0 (654, 738)

QLPVNRW
TRRQVILCGTCLIVSSVKDSLTGKMHVLPLIGGKVEEVKKH-QHCLAFSSSGPQSQTYYI
CFDTFTEYLRWLRQVSKVASQRISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLRQNP
SLPAARGLNELQRF-

PF13516 // ENSGT00440000037833_1_Domain_3 (796, 810)

TKLKSLNLSNNHLG

ENSGT00440000037833_1_Linker_3_4 (810, 819)

DFPLAVCSI

PF13855 // ENSGT00440000037833_1_Domain_4 (819, 876)

PTLAELNVSCNALRSVPAAVGV
MHNLQTFLLDGNFLQTLPAELENMKQLSYLGLSFNEFTDIPEVLEKLTAVDKLCMSGNCM
ETLRLQALRKMPHIKHVDLRLNIIRKLIA-DEVDFL

PF13516 // ENSGT00440000037833_1_Domain_8 (937, 952)

QHVTQLDLRDNKLGDLDAMIFNNI
EVLH----------------------C----------------ERNQLVTLDICGYF---
LKALYASSNELVQLDVYPVPNYLSYMDVSRNRLENVPEWVCESR

PF00560 // ENSGT00440000037833_1_Domain_10 (1065, 1086)

KLEVLDIGHNQICELP
ARLFCNSSLRKLLAGHNQLARLPERLERTSVEVLDVQHNQLLELPPNLLMKADSLRFLNA
SANKLESLPPATLSEETNS---I

PF13855 // ENSGT00440000037833_1_Domain_15 (1164, 1279)

LQELYLTNNSL----------------------TDKC
VPLLTGHPHLKILHMAYNRLQSFPA-SKMAK-----------------------------
-----LEELEEIDLSGNKLKAIPTTIMNCRRVHTVIAHSNCIEVFPEVMQLPEIKCVDLS
CNELSEVTLPENLPPKLQELDLTGNPRLVLDHKTLELLN-NIRCFKIDQPSTG----DAS
GAPAVWSH

PF00481 // ENSGT00440000037833_1_Domain_18 (1389, 1632)

GYTEASGVKNKLCVAALSVNNFCDNREALYGVFDGDRNVEVPYLLQCTMSDI
LAEELQKTKNEEEYMVNTFIVMQRKLGTAGQKLGGAAVLCHIKHDPVDPGGSFTLTSANV
GKCQTVLCRNGKPLPLSRSYIMSCEEELKRIKQHKAIITED-GKVN--GVTES-TRILG-
YTFLHPSVVPRPHVQSVLLTPQDEFFILGSKGLWDSLSLEEAVEAVRNVPDALAAAKKLC
TLAQSYGCHDSISAVVVQLSVTEDSFCCCELSAGGAVPPPSPGIFPPSVNMVIKDRPSDG
LGVPSSSSGMASEISSELSTSEMSSEVGSTASDEPP-PGALSE--NSPAYPSEQRCMLHP
VCLSNSFQRQLSS----ATFSSAFSDNGLDSDDEEPIEGVFTNGSRVE------VEVDIH
CSRAKEKEKQQ-HLLQVPAEASDEGIVISANEDEPGLPRK-ADFSAVGTIGRRRANGSVA
PQERSHNMIEVATDAPLRKPGGYFAAPAQPDPDDQFIIPPELEEEVKEIMKHHQEQQ---
QQQQ-PP---PP---P---------QL--QPQLPRHYQLDQLPDYYDTPL

MEPAAAAPAQRLPYPGSGEDRAPAV----------------AAAAAAAGGGQSPELALTP
AAA-S--CGSGGAREEAPSEAPPGPLPGRAG-GTGRRRRRGA-PQPTAGAAAPVSAAG--
-SGANSLLLRRGRLKRNLSAAAAVSSSSSS----SLSSSAASSNSPSATGLPASCSASAS
LCTRSLDRKTLLQKH-RQLLQLQPSDRDWVRHQLQRGCVHIFDRHMASTCLRPVLCTLDT
TAGEVAARLLQLGHK----GGGVVKVLGQGPRPTAA--G------------PRLEPPE--
-------CRD---SGAVGGPPRAPPA-DLPLPAGGP-------------R--------AS
PAPSDSSPGEPRP-----GGAASPPGAPRRLDGVV------SDSESFSLSPSAE--SVSD
RLDPYSSGSGSSSS-EDL-EA---------------------NPGQ-P-R-------CSG
RAAQSRPPSPTAAQPRPQQTASGGVDCRD-------GADREGP--RQKAAAAALGGALLI
--PGRSKGTLEK-------GPLPPTLYMQLHGETTRRLEADEKPLQIQNDYLFQLGFG--
ELWRVQ-EE---GMDSEIGCLIRFY--AGKPHSTGSSERIQLSGMYNVRKGRM

PF00169 // ENSGT00440000037833_1_Domain_0 (654, 738)

QLPVNRW
TRRHVILCGTCLIVSSVKDSLTGKMHVLPLIGGKVEEVKKH-QHCLSFSSSGPQSQTYYI
CFDTFTEYLRWLRQVSKVASQRISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLRQNP
SLPAARGLNELQRF-

PF13516 // ENSGT00440000037833_1_Domain_3 (796, 810)

TKLKSLNLSNNHLG

ENSGT00440000037833_1_Linker_3_4 (810, 819)

DFPLAVCSI

PF13855 // ENSGT00440000037833_1_Domain_4 (819, 876)

PTLTELNMSCNALRAVPAAVGA
MHNLQTFLLDGNFLQSLPAELENMHQLSYLGLSFNEFTDIPEVLEKLTAVDKLCMSGNCM
ETLRLQALRRMPHIKHVDLRLNIIRKLTA-DEVEFL

PF13516 // ENSGT00440000037833_1_Domain_8 (937, 952)

QHITQLDLRDNKLGDLDAMIFNNI
EVLH----------------------C----------------ERNQLVTLNICGYY---
LKALYAASNELVRLDVYPVPNYLSYMDVSRNHLENVPEWVCESRKLEVLDIGHNQICDLP
AHVFCNSSLRKLLAGHNQLARLPERLERTSVEVLDIQHNQLIELPPNLLLKADSLRFLNA
SANKLETLPPATLSEETNS---I

PF13855 // ENSGT00440000037833_1_Domain_15 (1164, 1279)

LQELYLTNNNL----------------------TDKC
VPLLTGHPHLKILHMAYNRLQSFPA-SKMAK-----------------------------
-----LEELEEIDISGNKLKAIPTTIMNCRRMHTVIAHSNSIEVFPEVMQLPEIKCVDLS
CNELSEVTLPENLPPKLQELDLTGNPRLALDHKTLELLN-NIRCFKIDQPSSG----DAS
GAPAVWSH

PF00481 // ENSGT00440000037833_1_Domain_18 (1389, 1632)

GYTEASGMKNKLCVAALSVNNFCDNREALYGVFDGDRNVEVPYLLQCTMSDI
LAEELQKTKNEEEYMVNTFIVMQRKLGTAGQKLGGAAVLCHIKHDPVDPGGSFTLTSANV
GKCQTVLCRNGKPLPLSRSYVMSCEEELKRIKQHKAIITED-GKVN--GVTES-TRILG-
YTFLHPSVVPRPHVQSVLLTPQDEFFILGSKGLWDSLSIEEAVEAVRNVPDALAAAKKLC
TLAQSYGCHDSISAVVVQLSVTEDSFCCCELSTGGSVPPPSPGIFPPSVNMVIKDRPSDG
LGVPSSSSGMASEISSELSTSEMSSEVGSTASDEPP-PGALNE--SSSAYPSEQRCTLHP
ICLSNSFQRQLSS----ATFSSAFSDNGLDSDDEEPIEGVFTNGSRVE------VEVDIH
CIRAKEKEKQQ-HLLQVPAEASDEGIVISANEDEPGLPRK-ADFSSVGTIGRRRANGSVA
PQERSHNVIEVAADAPLRKSGGYFAAPAQPDPDDQFIIPPELEEEVKEIMKHHQEQQ-QQ
PPQ------------IQ------------QQPLQRQFQMDQLPDYYDTPL

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-----------------------------KPHSSGSSERIQLSGMYNVRKGKM

PF00169 // ENSGT00440000037833_1_Domain_0 (654, 738)

QLPVNRW
TRRHVILCGTCLIVSSVKDSLTGKMHVLPLIGGKVEEVKKH-QHCLAFSSSGPQSQTYYI
CFDTFTEYLRWLRQVSKVASQRISSVDLSCCSLEHL------------------------
-------------F-

PF13516 // ENSGT00440000037833_1_Domain_3 (796, 810)

TKLKSLNLSNNHLGDFPLAVCSIPTLTELNVSCNALRAVPASVGA
MHN-------------------------YLGLSFNEFTDIPEVLEKLTAMDKLCMSGNCM
ETLRLQALRRMPHIKHVDLRLNIIRKLIA-DEVEFLQHXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLINE
INITIFQDKKLVQLDVYPVPNY

PF13855 // ENSGT00440000037833_1_Domain_10 (1043, 1099)

LSYMDVSRNRLENVPEWVFESRKLEVLDIGHNQICDLP
ARLFCNSSLRKLLAGHNQLARLPEXXXXXXXXXXXVQHNQLVELPPNLLLKADSLRFLNA
SANKLENLPPATLSEETNS---ILQEFKDTSNCI---------------------LSDSD
YVRLTGNPALRVAQPSGSEDDYYKPDFKVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMHTVIAHSNCIEVFPEVMQLPEIKCVDLS
CNELSEVTLPENLPPKLQELDLTGNPRLALDHKTLELLN-NIRCFKIDQSL---------
----------------LFRLCVAALSVNN

PF00481 // ENSGT00440000037833_1_Domain_18 (1410, 1632)

FCDNREALYGVFDGDRNVEVPYLLQCTMSDI
LAEELQKTKNEEEYMVNTFIVMQRKLGTAGQKLGGAAVXXXXXHDPVDPGGSFTLTSANV
GKCQTVLCRNGKPLPLSRSYVMSCEEELKRIKQHKAIITED-GKVN--GVTES-TRILG-
YTFLHPSVVPRPHVQSVLLTPQDEFFILGSKGLWDSLSIEEAVEAVRNVPDALAAAKKLC
TLAQSYGCHDSVSAVVVQLSVTEDSFCCCELATTGSVPPPSPGIFPPSVNMVIKDRPSDG
LGVPSSSSGMASEISSELSTSEMSSEVGSTASDEPPS-GALNE--SSSAYPSEQRCMLHP
VCLSNSFQRQLSS----ATFSSAFSDNGLDSDDEEPIEGVFTNGSRVE------VEVDIH
CSRAKEKEKQQ-HQLQMPAEASDEGIVISANEDEPGLPRK-ADFSSVGTIGRRRANGSVA
PQERSHNVIEVATDAPLRKPGGYFAAPAQPDPDDQFIIPPELEEEVKEIMKHHQEQQQQ-
----PP--------------------PLPQQPLQRQFPTDQLPDCYDTPL

MEPAAAATAQRLPETSREDRASAPAAAAAEAAAAA------AAALAAASGGRSPEPALTP
AAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXX-XXXXXXXXXXX-
-XXXXXXXXXXXXXXXXXXXXXXXXXXXX----XXXX----XXX--XXXXXX--------
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXX--------------XXXX
XXXX-XXXXXX--XXXXXXXXXXXXXXXXXXXXXXXX------------XXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-----X---XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXX----XXX--XXXXXXXXXXXXXX-------------X
XXX-XXXXX-XXXXXXXXXXXXXXXXXXX-------XXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXX-XX------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXX--XXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVEEVKKH-QHCLAFSSSGPQSQTYYI
CFDTFTEYLRWLRQVSKVASQ

PF00560 // ENSGT00440000037833_1_Domain_1 (742, 760)

RISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLRQNP
SLPTARGLNELQRF-T

PF00560 // ENSGT00440000037833_1_Domain_3 (797, 818)

KLKSLNLSNNHLGDFPLAVCNIPTLAELNVSCNALRAVPAAVGV
MH

PF00560 // ENSGT00440000037833_1_Domain_4 (843, 864)

NLQTFLLDGNFLQTLPAELEN

ENSGT00440000037833_1_Linker_4_6 (864, 866)

MH

PF00560 // ENSGT00440000037833_1_Domain_6 (866, 887)

QLSYLGLSFNEFTDIPEVLEKLTAVDKLCMSGNCM
ETLRLQALRKMPHMKHVDLRLNTIRKLIA-DEVDFLPHVTQLDLRDNK-GDLDAM-VNNI
EVLH----------------------C----------------ERNQLVTLNICGYF---
LKALYASSNELVQLDVYPVPNYLSYMDVSRNRLENVPEWVCESR

PF00560 // ENSGT00440000037833_1_Domain_10 (1065, 1087)

KLEVLDIGHNQICELP
ACLFCN

ENSGT00440000037833_1_Linker_10_11 (1087, 1088)

S

PF00560 // ENSGT00440000037833_1_Domain_11 (1088, 1106)

SLRKLLAGHNQLTRLPER

ENSGT00440000037833_1_Linker_11_12 (1106, 1110)

LERT

PF00560 // ENSGT00440000037833_1_Domain_12 (1110, 1128)

SVEVLDVQHNQLLELPPN

ENSGT00440000037833_1_Linker_12_13 (1128, 1134)

LLMKAD

PF00560 // ENSGT00440000037833_1_Domain_13 (1134, 1156)

SLRFLNA
SANKLETLPPATLSEETNS---ILQELYLTNNNL----------------------TDKC
VPLLTGHP

PF00560 // ENSGT00440000037833_1_Domain_15 (1209, 1266)

HLKILHMAYNRLQSFPA-SKMAK-----------------------------
-----

ENSGT00440000037833_1_Linker_15_16 (1266, 1268)

LE

PF00560 // ENSGT00440000037833_1_Domain_16 (1268, 1289)

ELEEVDISGNKLKSIPTTIIN

ENSGT00440000037833_1_Linker_16_17 (1289, 1336)

CRRMHTVIAHSNCIEVFPEVMQLPEIKCVDLS
CNELSEVTLPENLPP

PF00560 // ENSGT00440000037833_1_Domain_17 (1336, 1358)

KLQELDLTGNPRLALDHKTLELLN-NIRCFKIDQPSAG----DAS
GAPAVWSHGYTEASGVKNKLCVAALSVNNFCDNREALYGVFDGDRNVEVPYLLQCTMSDI
LAEELQKTKNEEEYMVNTFIVMQRKLGTAGQKLGGAAVLCHIKHDPXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXX-XXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---XXXX-XXXXXXXXXXXXXXXXXXXX
XXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXX--XXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXLDSDDEEPIEGVFSNGSRVE------VEVDIH
CSRAKEKERQQ-HLLQVPAEASDEGIVISANEDEPGLPRK-ADFATVGTMGRRRPNGSVA
PQERSHNVIEVATDAPLRKPGGYFAAPAQPDPDDQFIIPPELEEEVKEIMKHHQQQQPP-
------------PPPPPPP------Q-LHLQQPQRQCPAEQLPDCCDTPL

MEPAAAATAQRLPETSREDRASAPAAAAAAAA----VAAAAAALAAAAGGSRSPEPALTL
AAPSGGNGGSGGAREEAAGEAPPGPLPVRAG-GTGRRRRRGA-PQPTAGGVAPVSGVGS-
--GANSLLLRRGRLKRNLSAAAAAASSSSS--SSSSSSAAAASHSAGASGLPASCSASAS
LCTRSLDRKTLLLKH-RQIMQLQPSDRDWVRHQLQRGCVHVFDRHMASTYLRPVLCTLDT
TAGEVAARLLQQGHK----GGGVVKVLGQGFGPAAARSGAEL----PPDAGPRLAPPEPR
DLEPPPARSA---LGAVGDTPRAPPA-DLALPGGGR-------------GGWARCTSRAS
PAPSDSSPGEPFA-----RGPASPPGTPRPLA---------SDTESFSLSPSAE--SVSD
RLDPYSSGGGSSSS-SEELDTDPA-----------PAPAPTGAPGQ-TRR----------
--------PAPASPPWPQQKARRGVDSPG-------GVARDETWGEKVAAAAAPSGPQ--
STPGRSGAAAEKAPPPP----PPPTLYVQLHGETTRRLEADEKPLQIQNDYLFQLGFG--
ELWRVQE----EGMDSEIGCLIRFY--AGKPHSTGSSERIQLSGMYNVRKGKM

PF00169 // ENSGT00440000037833_1_Domain_0 (654, 738)

QLPVNRW
TRRQVILCGTCLIVSSVKDSLTGKMHVLPLIGGKVEEVKKH-QHCLAFSSSGPQSQTYYI
CFDTFAEYLRWLRQVSKVASQRISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLRQNP
SLPAARGLNELQRF-

PF13516 // ENSGT00440000037833_1_Domain_3 (796, 810)

TKLKSLNLSNNHLGDFPLAVCSIPTLAELNVSCNALRAVPAAVGD
MHNLQTFLLDGNFLQSLPAELENMQQLSYLGLSFNEFTDIPEVLEKLTAVDKLCMSGNCM
ETLRLQALRKMPHIKHVDLRLNVIRKLIA-DEVDFL

PF13516 // ENSGT00440000037833_1_Domain_8 (937, 952)

QHVTQLDLRDNKLGDLDAMIFNNI
EVLH----------------------C----------------ERNQLVTLNICGYF---
LKALYASSNELVQLDVYPVPNYLSYMDVSRNRLENVPEWVCESRKLEVLDIGHNEICELP
ARLFCNSSLRKLLAGHNQLARLPERLERTSVEVLDVQHNQLLELPPNLLMKADSLRFLNA
SANKLETLPPATLCEETNS---I

PF13855 // ENSGT00440000037833_1_Domain_15 (1164, 1279)

LQELYLTNNSL----------------------TDKC
VPLLTGHPHLKILHMAYNRLQSFPA-SKMAK-----------------------------
-----LEELEEIDISGNKLKAIPTTIMNCRRMHTVIAHSNCIEVFPEVMQLPEIKCVDLS
CNELSEVTLPENLPPKLQELDLTGNPRLVLDHKTLELLN-NIRCFKIDQPSAG----DTS
GAPAVWSH

PF00481 // ENSGT00440000037833_1_Domain_18 (1389, 1632)

GYTEASGVKNKLCVAALSVNNFCDNREALYGVFDGDRNVEVPYLLQCTMSDI
LAEELQKTKNEEEYMVNTFIVMQRKLGTAGQKLGGAAVLCHIKHDPVDPGGSFTLTSANV
GKCQTVLCRNGKPLPLSRSYVMSCEEELKRIKQHKAIITED-GKVN--GVTES-TRILG-
YTFLHPSVVPRPHVQSVLLTPQDEFFILGSKGLWDSLSVEEAVEAVRNVPDALAAAKKLC
TLAQSYGCHDSISAVVVQLSVTEDSFCCCELSAGGSVPPPSPGIFPPSVNMVIKDRPSDG
LGVPSSSSGMASEISSELSTSEMSSEVGSTASDEPP-SGALNE--SSPACPSEQRCMLHP
VCLSNSFQRQLSS----ATFSSAFSDNGLDSDDEEPIEGVFINGSRVE------VEVDIH
CSRAKEKEKQQ-HLLQVPAEASDEGIVISANEDELGLPRK-ADFSAVGTIGRRRANGSVA
PQERSHNVIEVATDAPLRKPGGYFAAPAQPDPDDQFIIPPELEEEVKEIMKHHQEQQQQP
QLQQ--------------------------PQPQRHYQADQLPDYYDTPL

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----------------P----PPPTLYVQLHGETTRRLEAEEKPLQIQNDYLFQLGFG--
ELWRVQE----EGMDSEIGCLIRFY--AGKPHSTGSSERIQLSGMYNVRKGKM

PF00169 // ENSGT00440000037833_1_Domain_0 (654, 738)

QLPVNRW
TRRQVILCGTCLIVSSVKDSLTGKMHVLPLIGGKVEEVKKH-QHCLAFSSSGPQSQTYYI
CFDTFTEYLRWLRQVSKVASQRISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLRQNP
SLPAARGLNELQRF-

PF13516 // ENSGT00440000037833_1_Domain_3 (796, 810)

TKLKSLNLSNNHLG

ENSGT00440000037833_1_Linker_3_4 (810, 819)

DFPLAVCNI

PF13855 // ENSGT00440000037833_1_Domain_4 (819, 876)

PTLAELNVSCNALRSVPADVGV
MHNLQTFLLDGNFLQSLPAELENMKQLSYLGLSFNEFTDIPEVLEKLTAMDKLCMSGNCM
ETLRLQALRKMPHIKHVDLRLNVIRKLIA-DEVDFL

PF13516 // ENSGT00440000037833_1_Domain_8 (937, 952)

QHVTQLDLRDNKLGDLDAMIFNNI
EVLH----------------------C----------------ERNQLVTLDICGYF---
LKALYASSNELVQVDVYPVPNYLSYMDVSRNRLENVPEWVCESR

PF00560 // ENSGT00440000037833_1_Domain_10 (1065, 1086)

KLEVLDIGHNQICELP
ARLFCNSSLRKLLAGHNQLARLPERLERTSVEVLDVQHNQLQELPPNLLMKADSLRFLNA
SANKLESLPPATLSEETNS---I

PF13855 // ENSGT00440000037833_1_Domain_15 (1164, 1279)

LQELYLTNNSL----------------------TDKC
VPLLTGHPHLKILHMAYNRLQSFPA-SKMAK-----------------------------
-----LEELEEIDLSGNKLKAIPTTIMNCRRMHTVIAHSNCIEVFPEVMQLPEIKCVDLS
CNELSEVTLPENLPPKLQELDLTGNPRLVLDHKTLELLN-NIRCFKIDQPSTG----DAS
GAPAVWSH

PF00481 // ENSGT00440000037833_1_Domain_18 (1389, 1632)

GYTEASGVKNKLCVAALSVNNFCDNREALYGVFDGDRNVEVPYLLQCTMSDI
LAEELQKTKNEEEYMVNTFIVMQRKLGTAGQKLGGAAVLCHIKHDPVDPGGSFTLISANV
GKCQTVLCRNGKPLPLSRSYVMSCEEELKRIKQHKAIITED-GKVN--GVTES-TRILG-
YTFLHPSVVPRPHVQSVLLTPQDEFFILGSKGLWDSLSVEEAVEAVRNVPDALAAAKKLC
TLAQSYGCHDSISAVVVQLSVTEDSFCCCELSAGGAVPPPSPGIFPSSVNMVIKDRPSDG
LGVPSSSSGMASEISSELSTSEMSSEVGSTASDEPP-PGALSE--NSPAYPSEQRCMLHP
VCLSNSFQRQLSS----ATFSSAFSDNGLDSDDEEPIEGVFTNGSRVE------VEVDIH
CSRAKEKEK-Q-HLLQVPAEASDEGIVISANEDEPGLPRK-ADFSAVGTIGRRRANGSVA
PQERSHNVIEVAADAPLRKPGGYFAAPAQPDPDDQFIIPPELEEEVKEIMKHHQEQQ---
-QQQPPP---PP---P---------PL--QPQLPRHYQLDQLPDYYDTPL

MEPAAAATVQRLPELGREDRASAPAAAAAAAAA---AAAAAAALAAAAGGGRSPEPALTP
AAPSGGNGSGGGAREEAPGEAPLGPLPGRAG-GAGRRRRRGA-PQPIAGGAAPVPGAGG-
--GANSLLLRRGRLKRNLSAAAAAASSS------SSSSAAAASHSPGAAGLPASCSASAS
LCTRSLDRKTLLLKH-RQTLQLQPSDRDWVRHQLQRGCVHVFDRHMASTYLRPVLCTLDT
TAGEVAARLLQLGHK----GGGVVKVLGQGPGAAAAREPAEP----PPEAGPRLAPPEPR
DSEVPPARSA---PGAVGGPPRAPPA-DLPLPVGGP-------------GGWSR---RAS
PAPSDSSPGEPFV-----GGPVSSPRAPRPVV---------SDTESFSLSPSAE--SVSD
RLDPYSSGGG-SSSSSEELEADA-------------ASAPTGVPGQ-PR--------RPG
HPAQPLPLPQTASSPQPQQKAPRAIDSPG-------GAVXXXXXXXXXXXXXXXXXX--X
XXXXXXXXXXXXXXXPP----PPPTLYVQLHGETTRRLEAEEKPLQIQNDYLFQLGFG--
ELWRVQE----EGMDSEIGCLIRFY--AGKPHSTGSSERIQLSGMYNVRKGKM

PF00169 // ENSGT00440000037833_1_Domain_0 (654, 738)

QLPVNRW
TRRQVILCGTCLIVSSVKDSLTGKMHVLPLIGGKVEEVKKH-QHCLAFSSSGPQSQTYYI
CFDTFTEYLRWLRQVSKVASQRISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLRQNP
SLPAARGLNELQRF-

PF13516 // ENSGT00440000037833_1_Domain_3 (796, 810)

TKLKSLNLSNNHLGDFPLAVCSIPTLAELNVSCNALRSVPAAVGV
MHNLQTFLLDGNFLQSLPAELENMKQLSYLGLSFNEFTDIPEVLEKLTAVDKLCMSGNCV
ETLRLQALRKMPHIKHVDLRLNVIRKLIA-DEVDFL

PF13516 // ENSGT00440000037833_1_Domain_8 (937, 952)

QHVTQLDLRDNKLGDLDAMIFNNI
EVLH----------------------C----------------ERNQLVTLDICGYF---
LKGLYASSNELVQLDVYPVPNYLSYMDVSRNRLENVPEWVCESRKLEVLDIGHNQICELP
ARLFCNSSLRKLLAGHNQLARLPERLERTSVEVLDVQHNQLLELPPNLLMKADSLRFLNA
SANKLESLPPATLSEETNS---I

PF13855 // ENSGT00440000037833_1_Domain_15 (1164, 1279)

LQELYLTNNSL----------------------TDKC
VPLLTGHPHLKILHMAYNRLQSFPA-SKMAK-----------------------------
-----LEELEEIDLSGNKLKAIPTTIMNCRRMHTVIAHSNCIEVFPEVMQLPEIKCVDLS
CNELSEVTLPENLPPKLQELDLTGNPRLVLDHKTLELLN-NIRCFKIDQPSTG----DPS
GAPAVWSH

PF00481 // ENSGT00440000037833_1_Domain_18 (1389, 1632)

GYTEASGVKNKLCVAALSVNNFCDNREALYGVFDGDRNVEVPYLLQCTMSDI
LAEELQKTKNEEEYMVNTFIVMQRKLGTAGQKLGGAAVLCHIKHDPVDPGGSFTLTSANV
GKCQTVLCRNGKPLPLSRSYIMSCEEELKRIKQHKAIITED-GKVN--GVTES-TRILG-
YTFLHPSVVPRPHVQSVLLTPQDEFFILGSKGLWDSLSVEEAVEAVRNVPDALAAAKKLC
TLAQSYGCHDSISAVVVQLSVTEDSFCCCELSAGGAVPPPSPGIFPPSVNMVIKDRPSDG
LGVPSSSSGMASEISSELSTSEMSSEVGSTASDEPP-PGALSE--NSPAYPSEQRCMLHP
ICLSNSFQRQLSS----ATFSSAFSDNGLDSDDEEPIEGVFTNGSLVE------VEVDIH
CSRAKEKEKQQ-HLLQVPAEASDEGIVISANEDEPGLPRK-ADFSAVGTIGRRRANGSVA
PQERSHNVIEVATDAPLRKPGGYFAAPAQPDPDDQFIIPPELEEEVKEIMKHHQEQQQQQ
QQQQ-PP---PP---P---------QL--QPQLPRHYQLDQLPDYYDTPL

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----------------------VFI--SGKPHSTGSSERIQLSGMYNVRKGKM

PF00169 // ENSGT00440000037833_1_Domain_0 (654, 738)

QLPVNRW
TRRQVILCGTCLIVSSVKDSLTGKMHVLPLIGGKVEEVKKH-QHCLAFSSSGPQSQTYYI
CFDTFTEYLRWLRQVSKVASQRISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLRQNP
SLPAARGLNELQRF-

PF13516 // ENSGT00440000037833_1_Domain_3 (796, 810)

TKLKSLNLSNNHLG

ENSGT00440000037833_1_Linker_3_4 (810, 819)

DFPLAVCNI

PF13855 // ENSGT00440000037833_1_Domain_4 (819, 876)

PTLAELNVSCNALRSVPADVGV
MHNLQTFLLDGNFLQSLPAELENMKQLSYLGLSFNEFTDIPEVLEKLTAVDKLCMSGNCM
ETLRLQALRKMPHIKHVDLSLSVIWIVMS-L-----------------------------
------------------------------------------------------------
--WIFFPLLELVQVDVYPVPNYLSYMDVSRNRLENVPEWVCESR

PF00560 // ENSGT00440000037833_1_Domain_10 (1065, 1086)

KLEVLDIGHNQICELP
ARLFCNSSLRKLLVGHNQLARLPERLERTSVEVLDVQHNQLQELPPNLLMKADSLRFLNA
SANKLESLPPATLSEETNS---I

PF13855 // ENSGT00440000037833_1_Domain_15 (1164, 1279)

LQELYLTNNSL----------------------TDKC
VPLLTGHPHLKILHMAYNRLQSFPA-SKMAK-----------------------------
-----LEELEEIDLSGNKLKAIPTTIMNCRRMHTVIAHSNCIEVFPEVMQLPEIKCVDLS
CNELSEVTLPENLPPKLQELDLTGNPRLFLDHKTLELLN-NIRCFKIDQPSTG----DAS
GAPAVWSH

PF00481 // ENSGT00440000037833_1_Domain_18 (1389, 1631)

GYTEASGVKNKLCVAALSVNNFCDNREALYGVFDGDRNVEVPYLLQCTMSDI
LAEELQKTKNEEEYMVNTFIVMQRKLGTAGQKLGGAAVLCHIKHDPVDPGGSFTLTSANV
GKCQTVLCRNGKPLPLSRSYVMSCEEELKRIKQHKAIITED-GKVN--GVTES-TRILG-
YTFLHPSVVPRPHVQSVLLTPQDEFFILGSKGLWDSLSVEEAVEAVRNVPDALAAAKKLC
TLAQSYGCHDSLSAVVVQLSVTEDSFCCCELSAGGAVPPPSPGIFPSSVNMVIKDRPSDG
LGVPSSSSGMASEISSELSTSEMSSEVGSTASDEPP-PGALSE--NSPAYPSEQRCMLHP
VCLSNSFQRQLSS----ATFSSAFSDNGLDSDDEEPIEGVFTNGSRVE------VEVDIH
CSRAKEKEK-Q-HLLQVPAEASDEGIVISANEDEPGLPRK-ADFSAIGTIGRRRANGSVA
PQERSHNVIEVATDAPLRKPGGYFAAPAQPDPDDQFIIPPELEEEVKEIMKHHQE-----
--QQQPP---PP---P---------PL--QPQLPRHYQLDQLPDYYDTPL

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------GQHRGIISYMLPTG--
-----------PLAYLPIACLLVFV--LGKPHSIGSSERIQLSGMYNVRKGKL

PF00169 // ENSGT00440000037833_1_Domain_0 (654, 738)

QLPVNRW
TRRQVILCGTCLIVSSVKDSLTGKMHVLPLIGGKVEEVKKH-QHCLAFSSSGPQSQTYYI
CFDTFTEYLRWLRQVSKVASQRISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLRQKP
SLPAARGLGELQRF-

PF13516 // ENSGT00440000037833_1_Domain_3 (796, 810)

TKLKSLNLSNNHLG

ENSGT00440000037833_1_Linker_3_4 (810, 819)

DFPLAVCSI

PF13855 // ENSGT00440000037833_1_Domain_4 (819, 876)

PTLAELNVSCNALQEVPAAVGV
MHNLQTFLLDGNFLQSLPAELENMHQLNYLGLSFNEFTDIPEVLEKLTAVDKLCMSGNCL
ETLRLQALRRMPHIKHVDLRLNIIRKLIA-DEVDFLQHVTQLDLRDNKLASLDAMIFNNI
EVLH----------------------C----------------ERNQLVTLNICGYF---
LKSLYASSNELVQLDVYPVPNYLSYMDVSRNCLENVPEWVCESRKLEVLDIAHNQICELP
ARLFCNSSLRKLLAGHNQLARLPERLERTSVEVLDVQHNQLMELPPNLLMKADSLRFLNA
SANKLDTLPAATLSEETSS---I

PF13855 // ENSGT00440000037833_1_Domain_15 (1164, 1279)

LQELYLTNNNL----------------------TDKC
VPLLTGHPRLKILHMAYNRLQSFPA-SKMAK-----------------------------
-----LEELEEIDLSGNKLKAIPTTIMNCRRMHTVIAHSNCIEVFPEVMQLSEIKCVDLS
CNELSEVTLPENLPPKLQELDLTGNPRLALDHKTLELLN-NIRCFKIDQPLAG----DAS
GAPAVWSH

PF00481 // ENSGT00440000037833_1_Domain_18 (1389, 1632)

GYTEASGVKNKLCVAALSVNNFRDNREALYGVFDGDRNVEVPYLLQCTMSDI
LAEELQKTKNEEEYMVNTFIVMQRKLGTAGQKLGGAAVLCHIKHDPVDPGGSFTLTSANV
GKCQTVLCRNGKPLPLSRSYIMSCEEELKRIKQHKAIITED-GKVN--GVTES-TRILG-
YTFLHPSVVPRPHVQSVLLTPQDEFFILGSKGLWDTLSIEEAVEAVRNVPDALAAAKKLC
TLAQSYGCHDSISAVVVQLSVTEDSFCCCELSAGGSMPPPSPGIFPPSVNMVIKDRPSDG
LGVPSSSSGMASEISSELSTSEMSSEVGSTASDEPP-SGVLNE--NSPAYPNEQRCMLHP
VCLSNSFQRQLSS----ATFSSAFSDNGLDSDDEEPIEGVFSNGSRVE------VEVDIH
CSRAKEKERQQ-HLLQVPAEVSDEGIVISANEDEPSLPKK-ADFSAVGTIGRRRANGSVA
PQERSHNVIEVATDAPLRKPGGYFAAPAQPDPDDQFIIPPELEEEVKEIMKHHQEQQQQQ
QQQQQQL---PPPPQPQLPPPPQPQQLQPQQLPQRQFQMDQLPDYYDTPL

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------KPHSIGSSERIQLSGMYNVRKGKIHLPVNRW
TRRQAILCGTCLIVSSVKESQTGKMHVLPLIGGKVEEVKKH-QHCLAFSSSGPQSQTYYI
CFDNFTEYLRWLRQASKVASQ

PF00560 // ENSGT00440000037833_1_Domain_1 (742, 760)

RISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLKLNP
SPSTSRALSELQRF-T

PF00560 // ENSGT00440000037833_1_Domain_3 (797, 818)

KLKSLNLSNNNLGEFPLAVCS

ENSGT00440000037833_1_Linker_3_5 (818, 820)

IP

PF00560 // ENSGT00440000037833_1_Domain_5 (820, 841)

TLTELNVSCNALRSVPAVVGE

ENSGT00440000037833_1_Linker_5_4 (841, 843)

MH

PF00560 // ENSGT00440000037833_1_Domain_4 (843, 864)

NLQTFLLDGNFLQSLPDELEH

ENSGT00440000037833_1_Linker_4_6 (864, 866)

MH

PF00560 // ENSGT00440000037833_1_Domain_6 (866, 887)

QLSYVSLSFNEFTDIPGVLEK

ENSGT00440000037833_1_Linker_6_7 (887, 913)

LTAMDKLCMSGNCM
DTLNLQVLKRMP

PF00560 // ENSGT00440000037833_1_Domain_7 (913, 936)

HIKHVDLRLNSIRRLEA-DEIDF

ENSGT00440000037833_1_Linker_7_8 (936, 938)

LH

PF00560 // ENSGT00440000037833_1_Domain_8 (938, 960)

HVTQLDLRDNKLGELDATVFNN

ENSGT00440000037833_1_Linker_8_9 (960, 1042)

V
EVLH----------------------C----------------ERNQLVTLKTSGYF---
LKALYASSNELVHLDVHPVPN

PF00560 // ENSGT00440000037833_1_Domain_9 (1042, 1063)

YLTYMDISRNHLENLPEWVCD

ENSGT00440000037833_1_Linker_9_10 (1063, 1065)

SR

PF00560 // ENSGT00440000037833_1_Domain_10 (1065, 1087)

KLEVLDVGHNRISELP
ARLFYNSSLRKLLAGHNLLGRLPDRLERT

PF00560 // ENSGT00440000037833_1_Domain_12 (1110, 1128)

QVEVLDVQHNQLLELPSN

ENSGT00440000037833_1_Linker_12_13 (1128, 1134)

LLLKAD

PF00560 // ENSGT00440000037833_1_Domain_13 (1134, 1156)

SLRFLNA
SANKLEMLPPATLSEETHS---ILQELYLTNNNL----------------------TDKC
VPLLTGHP

PF00560 // ENSGT00440000037833_1_Domain_15 (1209, 1266)

HLKILHMAYNRLQSFPA-SKMAK-----------------------------
-----

ENSGT00440000037833_1_Linker_15_16 (1266, 1268)

LE

PF00560 // ENSGT00440000037833_1_Domain_16 (1268, 1289)

ELEEIDISGNKLKAIPTTIMN

ENSGT00440000037833_1_Linker_16_17 (1289, 1336)

CRRMHTVIAHSNCIEVFPEVMQLSEIKCVDLS
CNELSEITLPENLPP

PF00560 // ENSGT00440000037833_1_Domain_17 (1336, 1358)

KLQELDLTGNPRLALDHKTLEL

ENSGT00440000037833_1_Linker_17_18 (1358, 1386)

LN-NIRCFKIDQPSAG----DAS
GAPAV

PF00481 // ENSGT00440000037833_1_Domain_18 (1386, 1632)

WSHGYTEASGVKNKLCVAALSANNFCDNREALYGVFDGDRNVEVPYLLQCTMSDI
LAEELQKTKNEEEYMINTFIVMQRKLGTAGQKLGGSAVLCHIKHDPMDPGGCFTLTSANV
GKCQTVLCRNGKPLPLSRCYVMSCEEELKRIKQHKAIITED-GKVN--GVTDS-TRILG-
YTFLHPSVVPRPHVQSITLTPQDEFFILGSKGLWDSLSMDEAVEAVRNVPDALAAAKKLC
TLAQSYGCNDSISAVVVQLNVTEDSFCCCELN---GVPPPSPGIFPQSVNVVIKDRPADA
LGMPSSSSGMASEISSEISTSEMSSEVGSTASDEPP-QVAMNE--SSPAYPGEQRCMLHP
VCLSNSFQRQLSS----ATFSSAFSDNGLDSDDEEPIEGVFTNGSRVE------VEVDIH
CSRAKEKQ---L--LQVPVEASDEGIVISANEDEPGLPKK-AEYSATGTIGRRRGNGSVA
PQERSHNLIEVATDAPLRKTGGYFAAPAQPDPDDQFIIPPELEEEVKEIMKQHQEQQ---
--------------------------------------------------

-------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXX-XXXXXXXXXXXXXXXX-
--XXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXK----GGGVVKVLGQGPGAAAAREPAEP----PPEAGPRLAPPEPR
DSEALPARSA---PGAVGGPPRAPPA-DLPLPAGVP-------------GGWSR---RAS
PAPSDSSPGEAFV-----GGPASSPRALRPVA---------SDTESFSLSPSAE--SVSD
RLDPYSSGGG-SS-SSEEVEADA-------------ASAPTGVPGQ-PR--------RPG
RSAQPLPPSQTASSPQPQQKAPRAVDSPG-------GAVREGPCEEKAAAFVAPGGLQST
--PGRSGVTAEKAP-------PPPTLYVQLHGETTRRLEAEEKPLQIQNDYLFQLGFG--
ELWRVQE----EGMDSEIGCLIRFY--AGKPHNTGSSERIQLSGMYNVRKGKM

PF00169 // ENSGT00440000037833_1_Domain_0 (654, 738)

QLPVNRW
TRRQVILCGTCLIVSSVKDSLTGKMHVLPLIGGKVEEVKKH-QHCLAFSSSGPQSQTYYI
CFDTFTEYLRWLRQVSKVASQRISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLRQNP
SLPAARGLNELQRF-

PF13516 // ENSGT00440000037833_1_Domain_3 (796, 810)

TKLKSLNLSNNHLG

ENSGT00440000037833_1_Linker_3_4 (810, 819)

DFPLAVCSI

PF13855 // ENSGT00440000037833_1_Domain_4 (819, 876)

PTLAELNVSCNALRSVPAAVGV
MHNLQTFLLDGNFLQSLPAELENMKQLSYLGLSFNEFTDIPEVLEKLTAVDKLCMSGNCM
ETLRLQALRKMPHIKHVDLRLNIIRKLIA-DEVDFL

PF13516 // ENSGT00440000037833_1_Domain_8 (937, 952)

QHVTQLDLRDNKLGDLDAMIFNNI
EVLH----------------------C----------------ERNQLVTLDICGYF---
LKALYASSNELVQLDVYPVPNYLSYMDVSRNRLENVPEWVCESRKLEVLDIGHNQICELP
ARLFCNSSLRKLLAGHNQLARLPERLERTSVEVLDVQHNQLLELPPNLLMKSDSLRFLNA
SANKLESLPPATLSEETNS---I

PF13855 // ENSGT00440000037833_1_Domain_15 (1164, 1279)

LQELYLTNNSL----------------------TDKC
VPLLTGHPHLKILHMAYNRLQSFPA-SKMAK-----------------------------
-----LEELEEIDLSGNKLKAIPTTIMNCRRVHTVIAHSNCIEVFPEVMQLPEIKCVDLS
CNELSEVTLPENLPPKLQELDLTGNPRLVLDHKTLELLN-NIRCFKIDQPSTG----DAS
GAPAVWSH

PF00481 // ENSGT00440000037833_1_Domain_18 (1389, 1632)

GYTEASGVKNKLCVAALSVNNFCDNREALYGVFDGDRNVEVPYLLQCTMSDI
LAEELQKTKNEEEYMVNTFIVMQRKLGTAGQKLGGAAVLCHIKHDPVDPGGSFTLTSANV
GKCQTVLCRNGKPLPLSRSYIMSCEEELKRIKQHKAIITED-GKVN--GVTES-TRILG-
YTFLHPSVMPRPHVQSVLLTPQDEFFILGSKGLWDSLSVEEAVEAVRNVPDALAAAKKLC
TLAQSYGCHDSISAVVVQLSVTEDSFCCCELSAGGAVPPPSPGIFPPSVNVVIKDRPSDG
LGVPSSSSGMASEISSELSTSEMSSEVGSTASDEPP-PGALSE--NSPAYPSEQRCMLHP
VCLSNSFQRQLSS----ATFSSAFSDNGLDSDDEEPIEGVFTNGSRVE------VEVDIH
CSRAKEKEKQQ-HLLQVPAEASDEGIVISANEDEPGLPRK-ADFSAVGTIGRRRANGSVA
PQERSHNVIEVATDAPLRKPGGYFAAPAQPDPDDQFIIPPELEEEVKEIMKHHQEQQ---
QQQQ-PP---PP---P---------QL--QPQLPRHYQLDQLPDYYDTPL

---------------------------------------------------------MEP
AAAET--RAEGRAAAGGPG-PALTAAPGRAG-GAARRRRRGPAPLPAAGGAAP-------
GPGASSLLLRRGRLKRNASAAAAP----------------------RPAGLPAPGPAAAP
PCSRSLDRRALLPR-PRQMLPLQPSDRDWVRHQLQRGCVHVLDRHSAASRLRPVLCTLDT
TAGEVASRLLQAGPR----AGGVLKVPGRAPAGPPPGKAALPA-----------------
----------------VGGPPPRRAS-------------------------------RAG
PAPAGCSPGSPRAP---DGAGR----T----------------PEPESPGPSPGAEGASR
PPDPYCSS-------------------SSEELEADPGQ---------PRLRGR------S
SGSRPL----SPAASPPPPTAPRGVEGSG-------GAARDRPAE------ESPGGD---
-------------AAAAEKAPPPPTLYVQLHGETARRLEADEKPLQIQNDYLFQLGFG--
ALWRVQE----EGLDSEVGCLIRFY--AGKPHSTGSSERIQLSGMYNVRKGKM

PF00169 // ENSGT00440000037833_1_Domain_0 (654, 738)

HLPVNRW
TRRQVILCGTCLIVSSVKDSVAGKMHVLPLIGGKVEEVKKH-QHCLALSSSGPQSQTYYI
CFDTFTEYLRWLRQVSKVASQRVSSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLRQNP
SLPTARGLSELQRF-

PF13516 // ENSGT00440000037833_1_Domain_3 (796, 810)

TKLKSLNLSNNHLGDFPLAVCNIPTLAELNVSCNALRAVPAAVGA
MCNLQTFLLDGNFLQTLPAELENMHQLSYLGLSFNEFTDFPEVLEKLTAVDKLCMSGNCM
ETLRLQALRKMPHIKHVDLRLNLIRKLVA-DGVDFL

PF13516 // ENSGT00440000037833_1_Domain_8 (937, 953)

PHVTQLDLRDNQLGNLDATVFSGL
EVLH----------------------C----------------ERNQLVALGLCGCV---
LKALHAASNELVQLDVSPVPNYLSYVDVSRNCLENVPEWVCESRKLEVLDIGHNQICELP
ARLFCNSGLRKLLAGHNRLARLPERLERTSVEVLDVQHNQLLELPPSLLMKADSLRFLNA
SANKLETLPPATLSEETSS---I

PF13855 // ENSGT00440000037833_1_Domain_15 (1164, 1279)

LQELYLTNNNL----------------------TDKC
VPLLTGHPHLKILHMAYNRLQSFPA-SKMAK-----------------------------
-----LEELEEIDLSGNKLKAVPTTIMSCRRMHTVTAHSNCIEVFPEVMQLPEIKCVDLS
CNELSEVTLPENLPPKLQELDLTGNPRLALDHRTLELLN-NIRCFKIDQPSAG----DAS
GAPAVWSH

PF00481 // ENSGT00440000037833_1_Domain_18 (1389, 1631)

GYTEASGVKNKLCVAALSVNNFRDNREALYGVFDGDRNMEVPNLLQCTMSDI
LAEELQRSRSGEECMVNTFLVMQRKLGTAGQKLGGAAVLCHIRHDPVDPGGPFTLTSANV
GKCQTVLCRSGEPLPLSRSYAVSCEEELQRIKRHKAIITED-GKVN--GVTES-TRILG-
YTFLHPSVVPRPHVQSVALSPQDEFLILGSKGLWDSLSVEEAVGAVRSVPDALAAAKKLC
TLAQSYGCRESVSAVVVQLSVPEDSFCCCELA---ALPPPSPSVFAPATSVAVRERPADG
LGAPSSSSGLTSEMSSELSTSEMSSEVGSTASDEPPPPGVLVE--GSPAGPGEPRCALHP
GGAPGAFQRQLSS----ATFSSAFSDNGLDSDDEEPIEGVFSNGSRVE------VAVDIH
CGRARDGELRRPPAPGPPPEAADEGSG--TAEDEPGAARR-AD-GAAGTMGRRRGNGSVA
PQERSHNVIEVAADAPLRRPGGYFAAPAQPDPDDQLIIPPELEEEVKEMMRQRPPAPPR-
-------------PGPAEPA--D--------------------CRCDTPL

MEPAAAATAQRLPEPGREDLASAPAAA-------------AAALAAAAGGGRSPEPALTP
AAPSGGNGSGGGAREEAPGEAPPGPLPGRAG-GAGRRRRRGA-PQPIAGGAAPVPGAGG-
--GANSLLLRRGRLKRNLSAAASS---------SSSSSAAAASHSPGAAGLPASCSASAS
LCTRSLDRKTLLLKH-RQTLQLQPSDRDWVRHQLQRGCVHIFDRHMASTYLRPVLCTLDT
TAGEVAARLLQLGHK----GGGVVKVLGQGPGAAAAREPAEP----PPEAGPRLAPPEPQ
DSEVQPARSA---PGAVGGPPRAPPA-DLPLPAGGP-------------GMWSR---RAS
PAPSDSSPGEPFV-----GGPASSPRAPRPVA---------SDTESFSLSPSAE--SVSD
RLDPYSSGGGGSSSSSEELEADA-------------VSAPTGVPGQ-PR--------RPG
HPAQPLPPPQTASSPRPQQKAPRAIDSPG-------GAVREGSCEEKAAAAVAPGGLQST
--PGRSGVTAEKAPPPP----PPPTLYVQLHGETTRRLEAEEKPLQIQNDYLFQLGFG--
ELWRVQE----EGMDSEIGCLIRFY--AGKPHSTGSSERIQLSGMYNVRKGKMQLPVNRW
TRRQVILCGTCLIVSSVKDSLTGKMHVLPLIGGKVEEVKKH-QHCLAFSSSGPQSQTYYI
CFDTFTEYLRWLRQVSKVASQRISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLRQNP
SLPAVRGLNELQRF-T

PF00560 // ENSGT00440000037833_1_Domain_3 (797, 814)

KLKSLNLSNNHLGDFPLAVCSIPTLAELNVSCNALRSVPSAVGV
MHNLQTFLLDGNFLQSLPAELENMKQLSYLGLSFNEFTDIPEVLEKLTAVDKLCMSGNCM
ETLRLQALRKMPHIKHVDLRLNVIRKLIA-DEVDFLQHVTQLDLRDNKLGDLDAMIFNNI
EVLH----------------------C----------------ERNQLVTLDICGYF---
LKALYASSNELVQLDVYPVPNYLSYMDVSRNRLENVPEWVCESR

PF00560 // ENSGT00440000037833_1_Domain_10 (1065, 1086)

KLEVLDIGYNQICELP
ARLFCNSSLRKLLAGHNQLARLPERLERTSVEVLDVQHNQLLELPPNLLMKADSLRFLNA
SANKLESLPPATLSEETNS---ILQELYLTNNSL----------------------TDKC
VPLLTGHPHLKILHMAYNRLQSFPA-SKMAK-----------------------------
-----LEE

PF00560 // ENSGT00440000037833_1_Domain_16 (1269, 1288)

LEEIDLSGNKLKAIPTTIMNCRRMHTVIAHSNCIEVFPEVMQLPEIKCVDLS
CNELSEVTLPENLPPKLQELDLTGNPRLVLDHKTLELLN-NIRCFKIDQPSTG----DAS
GAPAVWSH

PF00481 // ENSGT00440000037833_1_Domain_18 (1389, 1632)

GYTEASGVKNKLCVAALSVNNFCDNREALYGVFDGDRNVEVPYLLQCTMSDI
LAEELQKTKNEEEYMVNTFIVMQRKLGTAGQKLGGAAVLCHIKHDPVDPGGSFTLTSANV
GKCQTVLCRNGKPLPLSRSYIMSCEEELKRIKQHKAIITED-GKVN--GVTES-TRILG-
YTFLHPSVVPRPHVQSVLLTPQDEFFILGSKGLWDSLSVEEAVEAVRNVPDALAAAKKLC
TLAQSYGCHDSISAVVVQLSVTEDSFCCCELSAGGAAPPPSPGLFPPSVSMVIKDRPSDG
LGVPSSSSGMASEISSELSASEMSSEVGSTASDEPP-PGALSE--NSPAYPSEQRCMLHP
VCLSNSFQRQLSS----ATFSSAFSDNGLDSDDEEPIEGVFTNGSRVE------VEVDIH
CSRAKEKEKQQ-HLLQVPAEASDEGIVISANEDEPGLPRK-ADFSAVGTIGRRRANGSVA
PQERSHNVIEVATDAPLRKPGGYFAAPAQPDPDDQFIIPPELEEEVKEIMKHHQEQQQQQ
Q-QQ-LP---PP---P---------QL--QPQLPRHYQLDQLPDYYDTPL

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------VASQRISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLRQNP
SLPAARGLSELQRF-T

PF00560 // ENSGT00440000037833_1_Domain_3 (797, 814)

KLKSLNLSNNHLGDFPLAVCNIPTLTELNVSCNALRVVPAAVGV
MHNLQTFLLDGNALQSLPAEVGNMNQLSYLGLSFNEFTDIPEVLEKLTAVDKLCMSGNCL
ETLRLQALRKMPHIKNVDLRLNIIRKLIA-DEVDFLQHITQLDLRDNKLGDLDAMIFNNI
EVLH----------------------C----------------ERNQLVSLNICGYF---
LKALYASSNELVQLDVYPVPKYLSYMDISRNHLENVPEWVCESR

PF00560 // ENSGT00440000037833_1_Domain_10 (1065, 1086)

KLEVLDIGHNQICDLP
AHLFCNSSLRKLLAGHNQLTRLPERLERTSVEVLDVQHNQLLELPSTLLMKADSLRFLNA
SANKLETLPPATLSEETSS---ILQELYLTNNNL----------------------TDKC
VPLLTGHPHLKILHMAYNRLQSFPA-SKMAK-----------------------------
-----LEELEEIDISGNKLKAIPTTVMNCRRMHTVIAHSNCIEVFPEVMQLPEIKCVDLS
CNELSEVTLPENLPPKLQELDLTGNPRLALDHKTLELLN-NIRCFKIDQPSAG----DAS
GAPPVWSH

PF00481 // ENSGT00440000037833_1_Domain_18 (1389, 1632)

GYTEASGVKNKLCVAALSVNNFCDNREALYGVFDGDRNVEVPYLLQCTMSDI
LAEELQKTKNEEEYMVNTFIVMQRKLGTAGQKLGGAAVLCHIKHDPLDPGGSFTLTSANV
GKCQTVLCRNGKPLPLSRSYVMSYEEELKRIKQHKAIVTED-GKVN--GVTES-TRILG-
YTFLHPSVVPRPHVQSVTLSPQDEFFILGSKGLWESLSIEEAVEAVRNVPDALAAAKKLC
TLAQSYGCHDSISAVVVQLNVTEDSFCCCELSAGGSVPPPSPGIFPPSVSMVIKDRPSEG
LGVPSSSSGMASEISSEISTSEMSSEVGSTASDEPP-SGALNE--SSPAFPSEQRCMLHP
VCLSNSFQRQLSS----ATFSSAFSDNGLDSDDEEPIEGVFTNGSRVE------VEVDIH
CSRAKEREKQQ-HLLQLPAEVSDEGIVISANEDEPGIPRK-VDFSAVGTIGRRRANGSIA
PQERSHNVIEVATDAPLRKPGGYFAAPAQPDPDDQFIIPPELEEEVKEIMKHHQEQQQ--
-----P------------------------PPPQRQYQVEQLPDYYDTPL

ME---------------------------------------------------------P
AQQQQ-QQRAREAAERSPGGKGPATESGAEA-AGGPRRRRGA-AG---GSAPPAALAAPG
GAGGGSLLLRRGRLKRNLSAAAAP------------------------------------
LGTRSLDRKALLPKPPRQLQPLQPPERDWVRRDLQRGCVHVYERHA-NRYLRPVLCTLET
TAAEVAARLQQPGP----RGGGVVRVPGKAGPQPP-----------PPEEGPAAATAEPT
AEGE--------RPGSRRGTRGAPPAGGT------------------------EEGGSPS
P-------AAPPAELYLAGPPLSCP----------SLLGELGPAGSDCESFSPSAESVSD
RLDPYSSGGGGGSSSSDEL-------------EAEPAASDGAEAGAG-------------
------------------------------------------PGRG-----RPPPGELSP
G-AGG----------GREVPAGPPALFVQLHGETSRRLEGHEKPLQIQNDYLSQLGFR--
DLWRVQE----EGMDAETGCLIRFY--AGKPHSIGSSERIQLSGMYNVRKGKIH

PF00169 // ENSGT00440000037833_1_Domain_0 (655, 734)

LPVNRW
TRRQAILCGTCLIVSSVKESQTGKMHVLPLIGGKVEEVKKH-QHCLAFSSSGPQSQTYYI
CFDNFTEYLRWLRQASKVASQRISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLKLNP
SPSASRALSELQRF-

PF13516 // ENSGT00440000037833_1_Domain_3 (796, 810)

TKLKSLNLSNNNLGDFPLAVCSIPTLTELNVSCNALRNVPAVVGE
MHNLQTFLLDGNFLQSLPDELEHMHQLSYVSLSFNEFTDIPGVLEKLTAMDKLCMSGNCV
DTLNLQVLKRMPHIKHVDLRLNSIRRLEA-DEIDFLHHVTQLDLRDNKLGELDATIFNNV
EVLH----------------------C----------------ERNQLVTLKISGYF---
LKALYASSNELVHLDVYPVPNYLTYMDISRNHLENLPEWVCDSKKLEVLDVGHNRISELP
ARLFYNSSLRKLLAGHNLLGRLPDRLERTQVEVLDVQHNQLLELPPNLLLKADSLRFLNA
SANKLEMLPPATLSEETHS---I

PF13855 // ENSGT00440000037833_1_Domain_15 (1164, 1279)

LQELYLTNNNL----------------------TDKC
VPLLTGHPHLKILHMAYNRLQSFPA-SKMAK-----------------------------
-----LEELEEIDISGNKLKAIPTTIMNCRRMHTVIAHSNCIEVFPEVMQLSEIKCVDLS
CNELSEITLPENLPPKLQELDLTGNPRLALDHKTLELLN-NIRCFKIDQPSAG----DAS
GAPAVWSH

PF00481 // ENSGT00440000037833_1_Domain_18 (1389, 1632)

GYTEASGVKNKLCVAALSANNFCDNREALYGVFDGDRNVEVPYLLQCTMSDI
LAEELQKTKNEEEYMINTFIVMQRKLGTAGQKLGGSAVLCHIKHDPMDPGGCFTLTSANV
GKCQTVLCRNGKPLPLSRCYVMSCEEELKRIKQHKAIITED-GKVN--GVTDS-TRILG-
YTFLHPSVVPRPHVQSITLTPQDEFFILGSKGLWDSLSMDEAVEAVRNVPDALAAAKKLC
TLAQSYGCNDSISAVVVQLNVTEDSFCCCELN---GVPPPSPGIFPQSVNVVIKDRPADA
LGMPSSSSGMASEISSEISTSEMSSEVGSTASDEPP-QVAMNE--SSPAYPGEQRCMLHP
VCLSNSFQRQLSS----ATFSSAFSDNGLDSDDEEPIEGVFTNGSRVE------VEVDIH
CSRAKEKQ---L--LQVPVEASDEGIVISANEDEPGLPKK-AEYSATGTIGRRRGNGSVA
PQERSHNLIEVATDAPLRKTGGYFAAPAQPDPDDQFIIPPELEEEVKEIMKQHQEQQQQQ
QQQ--------------------------QQQQQRQYQMDHLADYYDTPL

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------KPHSTSSSER

PF00169 // ENSGT00440000037833_1_Domain_0 (640, 740)

IQLSGMYNVRKGKMQLPVNRW
TRRQVILCGTCLIVSSVKDSLTGKMHVLPLIGGKVEEVKKH-QHCLAFSSSGPQSQTYYI
CFDTFTEYLRWLRQVSKVA

ENSGT00440000037833_1_Linker_0_1 (740, 742)

SQ

PF00560 // ENSGT00440000037833_1_Domain_1 (742, 760)

RISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLRQNP
GLPSTRGLSELQRF-T

PF00560 // ENSGT00440000037833_1_Domain_3 (797, 818)

KLKSLNLSNNHLGDFPLAVCNIPTLAELNVSCNALRAVPAAVGA
MH

PF00560 // ENSGT00440000037833_1_Domain_4 (843, 864)

NLQTFLLDGNFLQSLPAELEN

ENSGT00440000037833_1_Linker_4_6 (864, 866)

MH

PF00560 // ENSGT00440000037833_1_Domain_6 (866, 887)

QLSYLGLSFNEFIDIPEVLEKLAAVDKLCMSGNCL
ETLRLQALRRMPHIKHVDLRLNIIQKIIA-DGVDFLQHITQLDLRDNKLHELDAMIFNNI
EVLH----------------------C----------------ERNQLATLNICGYF---
LKALYASSNELVQLDVYPVPNYLSYMDVSRNHLENVPEWVCESR

PF00560 // ENSGT00440000037833_1_Domain_10 (1065, 1087)

KLEVLDIGHNHICELP
ARLFCNSSLRKLLAGHNQLARLPERLERT

PF00560 // ENSGT00440000037833_1_Domain_12 (1110, 1128)

SVEVLDVQHNQLLELPPN

ENSGT00440000037833_1_Linker_12_13 (1128, 1134)

LLMKAD

PF00560 // ENSGT00440000037833_1_Domain_13 (1134, 1156)

SLRFLNA
SANKLESLPPATLCEETNS---ILQELYLTNNNL----------------------TDKC
VPLLTGHP

PF00560 // ENSGT00440000037833_1_Domain_15 (1209, 1266)

HLKILHMAYNRLQSFPA-SKMAK-----------------------------
-----

ENSGT00440000037833_1_Linker_15_16 (1266, 1268)

LE

PF00560 // ENSGT00440000037833_1_Domain_16 (1268, 1289)

ELEEIDISGNKLKAIPTTILN

ENSGT00440000037833_1_Linker_16_17 (1289, 1336)

CRRMHTVIAHSNCIEVFPEVMQLPEVKCVDLS
CNELNEVTLPENLPP

PF00560 // ENSGT00440000037833_1_Domain_17 (1336, 1358)

KLQELDLTGNPRLVLDHKTLEL

ENSGT00440000037833_1_Linker_17_18 (1358, 1386)

LN-NIRCFKIDQPSAG----DAS
GAPAV

PF00481 // ENSGT00440000037833_1_Domain_18 (1386, 1632)

WSHGYTEASGVKNKLCVAALSVNNFCDNREALYGVFDGDRNVEVPYLLQCTMSDI
LAEELQKTKNEEEYMVNTFIVMQRKLGTAGQKLGGSAVLCHIKHDPVDPGGSFTLTSANV
GKCQTVLCRNGKPLPLSASYVMSCEEELKRIKQHKAIVTED-GKVN--GVTES-TRILG-
YTFLHPSVVPRPHVQSVLLTPQDEFFILGSKGLWDSLSIQEAVEAVRNVPDALAAAKKLC
HVAQSYGCHDSISAVVVQLSGAEDSFCCCELDASGSVRPP--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

MEPAA-------------------------------------------------------
-------------------AAPAQRLA---D-PAG--------------EDRAPAAAAEA
GGGANSLLLRRGRLKRNLSAAASSSSSP-------------SSASSAAGGLPASCSASAS
LCTRSLDRKTLLLKH-RQLLQLQPSDRDWVRHQLQRGCVHVFDRHMASSYLRPVLCTMDT
TAAEVAARLLQLGHK----GGGVVKVLGQGLPPVAAPAAAVQ----SPDAGL------GR
EVEPPPSSSV---PGAVGAPARAPPA-DLPLPG----------------SSWPHCAPRAS
PAPSDCSPGELFA-----GGLGSPPRAPHL----------ASDTESFSLSPSAE--SVSD
RLDPYSSGGGSSSSEELEADPAQ---------------LSTRAPGP-PP-------LRPS
RPAQPRPP-SPKTSPSLQPKAPRVVDGTG-------GMAGQGPREDKVVAAATPGGPPST
--PGRIRETAQ-------KTSSPPSLYVQFHGETTRRLEADEKPLQIQNDYLFQLGFG--
ELWRVQE----EGMDSEIGCLIRFY--AGKPHSTGSSERIQLSGMYNVRKGKM

PF00169 // ENSGT00440000037833_1_Domain_0 (654, 738)

QLPVNRW
TRRQVILCGTCLIVSSVKDSLSGKMHVLPLIGGKVEEVKKH-QHCLAFSSSGPQSQTYYI
CFDTFTEYLRWLRQVSKVASQRISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLRQSP
TLPAARGLGELQRF-TKLKSLNLSNNHLGVFPSAVCSIPTLAELNVSCNTLREVPAAVGA
MQNLQTFLLDGNFLQSLPAELMNMHQLSYLGLSFNEFTDIPEVLEKLTAVDKLCMAGNCM
ETLRLQALRRMPHIKHVDLRLNILRKLIA-DEVDFVPHVTQLDLRDNKLADLDAMVFNNI
EVLH----------------------C----------------ERNQLVTLNICGYF---
LKALYASSNELIQLDVYPVPNYLSYMDVSRNCLENVPEWVCESRKLEVLDIGHNQICELP
ARLFCNSSLRKLLAGHNQLTRLPERLERTSVEVLDVQHNQLIELPPNLLMKADSLRFLNA
SANKLETLPPATLSEETCS---I

PF13855 // ENSGT00440000037833_1_Domain_15 (1164, 1279)

LQELYLTNNSL----------------------TDKC
VPLLTGHPHLKILHMAYNRLQSFPA-SKMAK-----------------------------
-----LEELEELDISGNKLKAIPTTILNCRRMHTVIAHSNCIEVFPEVMQLPEVKCVDLS
CNELSEITLPENLPPKLQELDLTGNPRLALDHKSLELLN-NIRCFKIDQPSTG----DAS
GAPAVWSH

PF00481 // ENSGT00440000037833_1_Domain_18 (1389, 1631)

GYTEASGVKNKLCVAALSVNNFRDNREALYGVFDGDRNVEVPYLLQCTMSDI
LAEELQKTKNEDEYMVNTFIVMQRKLGTAGQKLGGAAVLCHIKHDPVDLGGSFTLTSANV
GKCQTVLCRNGKPLPLSRSYIMSCEEELKRIKQHKAIITED-GKVN--GVTES-TRILG-
YTFLHPSVVPRPHVQSVLLTPQDEFFILGSKGLWDSLSNEEAVEAVRNVPDALAAAKKLC
TLAQSYGCHESISAVVVQLSVTEDSFCCCELSAGGSMPPPSPGIFPPSVNMAIKDRPSDG
LGVPSSSSGMASEISSELSTSEMSSEVGSTASDEPP-SGVLNE--NSPAYPSEQRCMLHP
VCLSNSFQRQLSS----ATFSSAFSDNGLDSDDEEPIEGVFSNGSRVE------VEVDIH
CSRAKEKEKQQ-HLLQVPAEASDEGIVISANEDDSGFSKK-ADFSAVGTIGRRRANGSVA
PQERSHNVIEVATDAPLRKPGGYFAAPAQPDPDDQFIIPPELEEEVKEIMKHHQEQQQL-
-----PP---PQLPQPQ------------LPQAQRQFQVDHLPDCYDTPL

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------AIGF---------S--AARAPPPPTL--------------------ASPR
-----RRRRGR-------RRRPPPPR-PAPLPAERAG--------------AGGVGGRKA
AKPR-----RHGARQPIAGAPASPTGA------------PRTPDGSFSLSPSAE--SASD
RLDPYSGGGGG-------------STSSSDELDADPV------------PPGPSRRPARP
AQ--PQPPSPTVSPPPPPPQAPRDADGPE-------GAAGEGPRDDRRGTA-APGGPLAT
PASSG-----E------TVSPPPPALYVQLHGETTRRLEADEKPLQIQNDYLFQLGFG--
ELWRVQE----EGMDPEIGCLIRFY--AGKPHSTGSSERIQLSGMYNVRKGKMQLPVNRW
TRRQVTLCGTCLIVSSVKDSLAGKMHVLPLIGGKVEEVKRH-QHCLALSSAGPSSQTYCI
CLDTFAEYLRWLRQVSKIASQRISSVDLSCCSLEQLPANLFYSQDLTHLNLKQNFLRQNP
NLPAARGLSELQRF-TKLKSLNLSNNHLGEFPLAVCSI

PF13855 // ENSGT00440000037833_1_Domain_4 (819, 876)

PTLTELNVSCNALREVPAAAGA
MPNLQTFLLDGNFLQSLPAELENLRQLSYLSLSFN

ENSGT00440000037833_1_Linker_4_7 (876, 891)

EFTDIPEVLEKLAAV

PF13855 // ENSGT00440000037833_1_Domain_7 (891, 949)

DKLCLSGNRL
ETLRLQALRRLPHIKHVDLRLNVIRKLVA-DEVDFLQHVTQLDLRDNKLCELDAMIFNNI
EVLH----------------------C----------------ERNQLVTLNICGYF---
LKALYASCNELVQLDVYPVPNFLSYMDVSRNCLENVPEWVCESRKLEVLDIGHNQICELP
ARLLCNSSLRKLLAGHNQLARLPDRLQRTAVEVVDVQHNQLAELPACLFLKADSLRFLNA
SANKLETLPPATLSEESSS---V

PF13855 // ENSGT00440000037833_1_Domain_15 (1164, 1279)

LQELYLTNNRL----------------------TDKC
VPLLTGHPHLKILHMAYNRLQSFPA-SKMAK-----------------------------
-----LEELEEIDISGNKLRAVPTTILSCRRMHTVMAHSSCIEVFPEVMQLPEIKCVDLS
CNELTEVTLPENLPPKLQELDLTGNPRLALDHKTLELLN-NIRCFKIDQPSAG----DAP
GAPAVWSH

PF00481 // ENSGT00440000037833_1_Domain_18 (1389, 1632)

GYTEASGVKNKLCVAALSVNNFRDNREALYGVFEGDRNVEVPYLLQCTMSDI
LAEELQKTRSEEEYMANTFIVMQRKLGTAGQKLGGAAVLCHIKHDPMDPGGSFTLTSANV
GKCQTVLCRNGKPLPLSRSYAMSFEEELRRIKQHKAIITED-GKVN--GVTES-TRILG-
YAFLHPSVVPRPHVQSVLLTPHDEFFVLGSKGLWDSLSIEEAVEAVRNVPDALAAAKKLC
TLAQSYGCHDSISAVVVQLSVAEDSFCCCDLSTAGSVPPPSPGIFPPSVNMVIKDRPSDG
LGVPSSSSGMASEVSSELSTSEMSSEVGSTASDEPP-PAGTSE--GNPAYPSEPRCTLHP
VCLPNAFQRQLS---------SAFSDNGLDSDDEEPIEGVFSNGSRVE------VEVDIH
CGRAKEKDRQR-HQLQVPAEASDEGIVISANEDEPGLPRK-ADFSAVGTIGRRRANGSVA
PQERSHNVIEVATDAPLRKPGGYFAAPAQPDPDDQFIIPPELEEEVKEIMKHHQEQQQQ-
----PVPPS------------------QPQQLPQRPFPTDQLPDYDDTPL

------------------------------------------------------------
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---------------------------SGKPHSTGSSERIQLSGMYNVRKGKIHLPVNRW
TRRQAILCGTCLIVSSVKESQTGKMHVLPLIGGKVEEVKKH-QHCLAFSSSGPQSQTYYI
CFDNFTEYLRWLRQASKVASQ

PF00560 // ENSGT00440000037833_1_Domain_1 (742, 760)

RISSVDLSCCSLEQLPANLFYSQDLTHLNLKQNFLRLNP
SPSTSRALNELQRF-T

PF00560 // ENSGT00440000037833_1_Domain_3 (797, 818)

KLKSLNLSNNNLGDFPLAVCS

ENSGT00440000037833_1_Linker_3_5 (818, 820)

IP

PF00560 // ENSGT00440000037833_1_Domain_5 (820, 841)

TLTELNVSCNALRSVPAAVGE

ENSGT00440000037833_1_Linker_5_4 (841, 843)

MH

PF00560 // ENSGT00440000037833_1_Domain_4 (843, 864)

NLQTFLLDGNFLQSLPDELEH

ENSGT00440000037833_1_Linker_4_6 (864, 866)

MH

PF00560 // ENSGT00440000037833_1_Domain_6 (866, 887)

QLSYVSLSFNEFTDIPGVLEKLTAMDKLCMSGNCV
DTLNLQALKRMPHIKHVDLRLNSIRRLEA-AETDFLH

PF00560 // ENSGT00440000037833_1_Domain_8 (938, 960)

HVTQLDLRDNKLGELDATVFNN

ENSGT00440000037833_1_Linker_8_9 (960, 1042)

V
EVLH----------------------C----------------ERNQLVTLKISGYF---
LKALYASSNELAHLDVYPVPN

PF00560 // ENSGT00440000037833_1_Domain_9 (1042, 1063)

YLAYMDISRNHLESLPEWVCD

ENSGT00440000037833_1_Linker_9_10 (1063, 1065)

SR

PF00560 // ENSGT00440000037833_1_Domain_10 (1065, 1087)

KLEVLDVGHNRIRELP
ARLFYNSSLRKLLAGHNLLGRLPDRLERT

PF00560 // ENSGT00440000037833_1_Domain_12 (1110, 1128)

QVEVLDVQHNQLLELPSN

ENSGT00440000037833_1_Linker_12_13 (1128, 1134)

LLLKAD

PF00560 // ENSGT00440000037833_1_Domain_13 (1134, 1156)

SLRFLNA
SANKLEMLPPATLSEETHS---ILQELYLTNNNL----------------------TDKC
VPLLTGHP

PF00560 // ENSGT00440000037833_1_Domain_15 (1209, 1266)

HLKILHMAYNRLQSFPA-SKMAK-----------------------------
-----

ENSGT00440000037833_1_Linker_15_16 (1266, 1268)

LE

PF00560 // ENSGT00440000037833_1_Domain_16 (1268, 1289)

ELEEIDISGNKLKAIPTTIMN

ENSGT00440000037833_1_Linker_16_17 (1289, 1336)

CRRMHTVIAHSNCIEVFPEVMQLSEIKCVDLS
CNELSEITLPENLPP

PF00560 // ENSGT00440000037833_1_Domain_17 (1336, 1358)

KLQELDLTGNPRLALDHKTLEL

ENSGT00440000037833_1_Linker_17_18 (1358, 1386)

LN-NIRCFKIDQPSAG----DAS
GAPAV

PF00481 // ENSGT00440000037833_1_Domain_18 (1386, 1632)

WSHGYTEASGVKNKLCVAALSANNFCDNREALYGVFDGDRNVEVPYLLQCTMSDI
LAEELQKTKNEEEYMINTFIVMQRKLGTAGQKLGGSAVLCHIKHDPMDPGGCFTLTSANV
GKCQTVLCRNGKPLSLSRCYAMSCEEELKRIKQHKAIITED-GKVN--GVTDS-TRILG-
YTFLHPSVVPRPHVQSITLTPQDEFFILGSKGLWDSLSMDEAVEAVRNVPDALAAAKKLC
TLAQSYGCNDSISAVVVQLNVTEDSFCCCELN---GVPPPSPGIFPQSVNVVIKDRPADA
LGMPSSSSGMASEISSEISTSEMSSEVGSTASDEPP-QVAMNE--NSPAYPGEQRCMLHP
VCLSNSFQRQLSSATHSATFSSAFSDNGLDSDDEEPIEGVFTNGSRVE------VEVDIH
CSRAKEKQ---L--LQVPVEASDEGIVISANEDEPGLPRK-AEYSATGTIGRRRGNGSVA
PQERSHNLIEVATDAPLRKTGGYFAAPAQPDPDDQFIIPPELEEEVKEIMKQHQEQQQQQ
--Q--------------------------QQQQQRQYQMDHLADYYDTPL

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------------------------------------------------------------
------------------------------------------------------------
-------------MDSEIGCLIRFY--AGKPHSTSNSERIQLSGMYNVRKGKMQLPVNRW
TRRQVILCGTCLIVSSVKDSLTGKMHVLPLIGGKVEEVKKH-QHCLAFSSSGPQSQTYYI
CFDTFTEYLRWLRQVSKVASQRISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLRQNP
SLPTARGLNELQRF-T

PF00560 // ENSGT00440000037833_1_Domain_3 (797, 814)

KLKSLNLSNNHLGDFPLAVCNIPTLTELNVSCNALRAVPAAVGV
MHNLQTFLLDGNFLQALPAELENMHQLSYLGLSFNEFTDIPEVLEKLTAVDKLCMSGNCM
ETLRLQALRKMPHIKHVDLRLNILRKLIA-DEVDFLQHVTQLDLRDNKLGDLDAMIFNNI
EVLH----------------------C----------------ERNQLVTLNICGYF---
LKALYASSNELVQLDVYPVPNYLSYMDVSRNRLENVPEWICESR

PF00560 // ENSGT00440000037833_1_Domain_10 (1065, 1086)

KLEVLDIGHNQICELP
ARLFCNSSLRKLLAGHNQLTRLPERLERTSVEVLDVQHNQLLELPPNLLMKADSLRFLNA
SANKLETLPPATLSEETNS---ILQELYLTNNNL----------------------TDKC
VPLLTGHPHLKILHMAYNRLQSFPA-SKMAK-----------------------------
-----LEELEEIDISGNKLKAIPTTIMNCRRMHTVIAHSNCIEVFPEVMQLPEIKCVDLS
CNELSEVTLPENLPSKLQELDLTGNPRLTLDHKTLELLN-NIRCFKIDQPSAG----DAS
GAPAVWSH

PF00481 // ENSGT00440000037833_1_Domain_18 (1389, 1632)

GYTEASGVKNKLCVAALSVNNFCDNREALYGVFDGDRNVEVPYLLQCTMSDI
LAEELQKTKNEEEYMVNTFIVMQRKLGTAGQKLGGAAVLCHIRHDPVDPGGSFTLTSANV
GKCQTVLCRNGQPLPLSRSYVMSCEEELKRIKRHKAIITED-GKVN--GVTES-TRILG-
YTFLHPSVVPRPHVQSVPLTPQDEFFILGSKGLWDSLSIEEAVGAVRNVPDALAAAKKLC
TLAQSYGCHDSISAVVVQLSVTEDSFCCCELSAGGAVPPPSPGIFPPSVSMVIKDRPTDG
LGVPSSSSGMASEISSELSTSEMSSEVGSTASDEPP-SGALNE--NSPAYPSEQRCMLHP
VCLSNSFQRQLSS----ATFSSAFSDNGLDSDDEEPIEGVFTNGSRVE------VEVDIH
CSRAKEKEKQQ-HLLQVPAEASDEGIVISANEDEPGLPRK-VDFATVGTIGRRRANGSVA
PQERSHNMIEVATDAPLRKPGGYFAAPAQPDPDDQFIIPPELEEEVKEIMKHHQQQQ---
----QPPAQ------------------LPLQQPQRQCPADPLPDY-----

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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MMLNEKNVYKEVVCNIRCFKIDQPSSG----DAS
GAPAVWSH

PF00481 // ENSGT00440000037833_1_Domain_18 (1389, 1539)

GYTEASGVKNKLCVAALSVNNFCDSREALYGVFDGDRNVEVPYLLQCTMSDI
LAEELQKTKNEEEYMVNTFIVMQRKLGTAGQKLGGAAVLCHIKHDPTDPGGSFTLTSANV
GKCQTVLCRNGKPLPLSRSYVMSCEEERKRIKQHKAIITEVRRARFSPGWQGGGARVTAE
-----AGNI--PSLQGHKAEALNER-SRHHRGIMNXXXXXXXXXXXXXXXXXXX------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------PARVMLLHEETTGMLEAGGKPLQIQDDYLFQLGFG--
ELWRVQK----EGIDAEIGCLVRFY--AGKPHSTGSWERIQLSGMYNVRKGKMQLPVNRW
TRRQVILCGTCLIVSSVKDSMTGKMHVLPLIGGKVEEVKKH-QHCLAFSSSGPXXXXXXX
XXXXXXXXXXXXXXXXXVASQ

PF00560 // ENSGT00440000037833_1_Domain_1 (742, 760)

RISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLRHSS
SLPAARGLHELQXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXLNVIKKLIA-DEVEFLQ

PF00560 // ENSGT00440000037833_1_Domain_8 (938, 960)

HVTQLDLRDNKLGDLDATVFNNI
EVLH----------------------C----------------ERNQLVTLNICGYF---
LKALYASSNELVQLDVYPIPNYLSCMDISRNCLENVPEWVCESR

PF00560 // ENSGT00440000037833_1_Domain_10 (1065, 1087)

KLEVLDIGHNQICELP
TRLFCN

ENSGT00440000037833_1_Linker_10_11 (1087, 1088)

S

PF00560 // ENSGT00440000037833_1_Domain_11 (1088, 1109)

SLRKLLAGHNQLSRLPDRLER

ENSGT00440000037833_1_Linker_11_12 (1109, 1110)

T

PF00560 // ENSGT00440000037833_1_Domain_12 (1110, 1128)

CVEVLDVQHNQLLELPPN

ENSGT00440000037833_1_Linker_12_13 (1128, 1134)

LLMKAD

PF00560 // ENSGT00440000037833_1_Domain_13 (1134, 1156)

SLRFLNA
SANRLETLPPATLSEETSS---ILQELYLTNNTL----------------------TDKC
VPLLTGHP

PF00560 // ENSGT00440000037833_1_Domain_15 (1209, 1266)

HLKILHMAYNRLQSFPA-SKMAK-----------------------------
-----

ENSGT00440000037833_1_Linker_15_16 (1266, 1268)

LE

PF00560 // ENSGT00440000037833_1_Domain_16 (1268, 1289)

ELEEIDVSGNQLKAIPTTIMNCRRMHTVIAHSNCIEVFPEVMQLPEIKCVDLS
CNELSEVTLPENLPPKLQDLDLTGNPRLSLDHRTLELLN-NIRCFKIDQPSAG----DAS
GAPAV

PF00481 // ENSGT00440000037833_1_Domain_18 (1386, 1632)

WSHGYTEASGMKNKLCVAALSVNNFCDNREALYGVFDGDRNVEVPYLLQCTMSDI
LAEELQKTKREEEYMANTFIVMQRKLGTAGQKLGGAAVLCHIKHDPVDPGGSFTLTSANV
GKCQTVLCRNGKPLPLSRSYVMSCEEELRRIKQHKAIVTEE-GKVN--GVGES-TRIIG-
YTFVQPSVVPG-LVQSVRLTPQDECFIMGSKRLGDSLSTEEAVEAVRNVPDALAAAKKLC
TLAQGYSCHDSVSAVVVQLNVSEDSCCCCELGAGGPVPPPSPGLYPPSVSMVLKERPADG
LGVPSSSSGMASEISSEISTSEMSSEVGSTASDEPP-SGALSE--SSPAYPSEPRCMLHP
VCLASAFQRQLSS----ATFSSAFSDNGLDSEDEEPIEG---------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------MDSEIGCLIRFY--AGKPHSTGGSERIQLSGMYNVRKGKMQLPVNRW
TKRQVILCGTCLIVSSVKDSLTGKMHVLPLIGGKVEEVKKH-QHCLAFSSSGPQSQTYYI
CFDTFTEYLRWLRQVSKVASQRISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLRQNP
SSPASRGLGELKRF-T

PF00560 // ENSGT00440000037833_1_Domain_3 (797, 814)

KLKSLNLSNNHLGDFPLAVCNIPTLTELNVSCNALRTVPATAGD
MHKIFIVLLDGNYLQSLPAELENMQQLSYLGLSFNEFTDIPKVLEKLTAVDKLCMSGNCM
EMLNLQALRRMPHIKHVDLRLNIIRKLMV-QELDFLPHVTQLDLRDNKLGDLDATVFNNL
EVLH----------------------C----------------ERNQLVTLNVCGYL---
LKALYASSNELVQLDIYPVPNHLTFMDVSRNHLESVPEWVCESR

PF00560 // ENSGT00440000037833_1_Domain_10 (1065, 1085)

KLEVLDIGHNQIRELP
ARLFYNSSLRKLLVGHNQLTKLPERLERTQVEVLDVQHNQLVELPPNLLMKADSLRFLNA
SANKLETIPPATLSEETSS---ILQELYLTNNHL----------------------TDKC
VPLLIGHPHLKILHMAYNRLQSFPA-SKMAK-----------------------------
-----LEELEEIDISGNKLKAIPTTIMNCRRMHTVIAHSNSIEVFPEVMQLTEIKCVDLS
CNELSEVTLPENLPSKLQELDLTGNPRLSLDHKTLELLN-NIRCFKIDQPSAG----DAS
GAPAVWSHG

PF00481 // ENSGT00440000037833_1_Domain_18 (1390, 1632)

YTEASGVKNKLCVAALSANNFCDNREALYGVFDGDRNVEVPYLLQCTMSDI
LAEELQKTKNEEEYMVNTFIVMQRKLGTAGQKLGGSAVLCHIKHDPMDPGGYFTLTSANV
GKCQTVLCRNGKPLPLSKSYIMSCEEELKRIKQHKAIITED-GKVN--GVTES-TRILG-
YTFLHPSVVPRPHVQSVTLTPQDEFFILGSKGLWDSLSIEEAVEAVRNVPDALAAAKKLC
TLAQSYGCNDSISAVVVQLNVTEDSFCCCELTGS-GVPPPSPGIFPPSVNVVIKDRPSDG
LGVPSSSSGMASEISSEISTSEMSSEVGSTASDEPP-PGALSE--SSPAYPSEQRCMLHP
VCLSGSFQRQLSS----ATFSSAFSDNGLDSDDEEPIEGVFTNGSRVE------VEVDIH
CGQAKEREKQQQLLPQVPTEASDEGIVISANEDEVGLPRK-PDFSATGTIGRRRGNGSVA
PQERSHNMIEVAADAPLRKTGGYFAAPAQPDPDDQFIIPPELEEEVKEIMKHHQEQQQQQ
QQQQQ-QQQ------------------QQQQQQQRQYQMDQLPDYYDTPL

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-----------------------------KPHSIGSSERIQLSGMYNVRKGKMQLPVNRW
TRRQVILCGTCLIVSSVXXXXXXXXXXXXXXXXXVEEVKKH-QHCLAFSSSGPQSQTYYI
CFDTFTEYLRWLRQVSKVASQ

PF00560 // ENSGT00440000037833_1_Domain_1 (742, 760)

RISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLRRNS
SLPAARGLSELQRF-T

PF00560 // ENSGT00440000037833_1_Domain_3 (797, 818)

KLKSLNLSNNHLGDFPLAVCN

ENSGT00440000037833_1_Linker_3_5 (818, 820)

IP

PF00560 // ENSGT00440000037833_1_Domain_5 (820, 841)

TLTELNVSCNALRAVPAAVGV

ENSGT00440000037833_1_Linker_5_4 (841, 843)

MH

PF00560 // ENSGT00440000037833_1_Domain_4 (843, 864)

NLQTFLLDGNFLQSLPAELEN

ENSGT00440000037833_1_Linker_4_6 (864, 866)

MH

PF00560 // ENSGT00440000037833_1_Domain_6 (866, 887)

QLSYLGLSFNEFTDIPEVLEKLTAMDKLCMSGNCL
ETLG-QALRKMPHIKHVDLKLNIIRKLIA-DEVDFLQHITQLDLRNNKLGDLDAMIFNNL
EVLH----------------------C----------------ERNQLISLNICGYF---
LKALYASFNELVQLDVYPVPNYLSYMDISRNRLENVPEWVCESR

PF00560 // ENSGT00440000037833_1_Domain_10 (1065, 1083)

KLEVLDIGHNQICELP
AXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLRFLNA
SANKLEALPPATLSEETNS---ILQELYLTNNNL----------------------TDKC
VPLLTGHP

PF00560 // ENSGT00440000037833_1_Domain_15 (1209, 1266)

HLKILHMAYNRLQSFPA-SKMAK-----------------------------
-----

ENSGT00440000037833_1_Linker_15_16 (1266, 1268)

LE

PF00560 // ENSGT00440000037833_1_Domain_16 (1268, 1289)

ELEEIDISGNKLKAIPTTVMN

ENSGT00440000037833_1_Linker_16_17 (1289, 1336)

CRRMHTVIAHSNCIEVFPEVMQLPEIKCVDLS
CNELSDITLPENLPP

PF00560 // ENSGT00440000037833_1_Domain_17 (1336, 1358)

RLQELDLTGNPRLALDHKTLEL

ENSGT00440000037833_1_Linker_17_18 (1358, 1386)

LN-NIRCFKIDQPSAG----DAS
GAPAV

PF00481 // ENSGT00440000037833_1_Domain_18 (1386, 1632)

WSHGYTEASGVKNKLCVAALSVNNFCDNREALYGVFDGDRNIEVPYLLQCTMSDI
LAEELQKTKNEEEYMVNTFIVMQRKLGTAGQKLGGAAVLCHIKHDPVDPGGAFTLTTANV
GKCQTVLCRNGKPLPLSRSYVMSCEEELKRIKQHKAIITED-GKVN--GVTES-TRILG-
YTFLHPSVVPRPHVQSVTLSPQDEFFILGSKGLWESLSVEEAVEAVRNVPDSLAAAKKLC
TLAQSYGCHDSISAVVVQLNVPEDSFCCCELSAGGGVPPPSPGIFPPSVNMVIKDRPSEG
LGVPSSSSGMASEISSEISTSEMSSEVGSTASDEPP-SGALNE--SSPAYPSEQRCMLHP
VCLSSSFQRQLSS----ATFSSAFSDNGLDSDDEEPIEGVFTNGSRVE------VEVDIH
CSQARERDKQQ-HLLPLPAEASDEGIVISANEDEPGLPRK-ADFSAVGTIGRRRANGSVA
PHERSHNVIEVATDAPLRKPGGYFAAPAQPDPDDQFIIPPELEEEVKEIMKHHQEQQQP-
------------PPP------------QLQPPPPRQYQLDPLPDYYDTPL

MEPAAAAPAQRLADPTGEDQALAA---------------------AAAEGGRCPDPALSA
AAPSGGN--GGAAREEAPCEAPPGPLPGRAG-GTGRRRRRGA-PQPAAGGAAPVPAAGG-
--GANSMLLKRGRLKRNLSAAAAASSSSSP-----------SSASSAAGGLPASCSASAS
LCTRSLDRKTLLLKH-RQLLQLQPSDRDWVRHQLQRGCVHVFDRHMASSYLRPVLCTLDT
TAAEVAARLLQLGHK----GGGVVKVLGHGRPPAAAPAASDQ----TPDRELG------T
DVEPPPSSGT---VGAVRGPARAPPA-DLPLPGG----------------AWTRCAPRVS
PAPSDSSPGELFA-----GGPGSPPRAPRPA----------SDTESFSLSPSAE--SVSD
RLDPYSSGGGGSSSSSEELEADPA-----------M-------------------PHRPG
RPAQP-RPPSPKTSALLQPKAPTGVDSTG-------VIAREGPGDDKAMAAAAPE----G
--PGRIRETVQ-------KTSSPPSLYVQLHGETTRRLEADEKPLQIQNDYLFQLGFG--
ELWRVQE----EGMDSEIGCLIRFY--AGKPHSTGSSERIQLSGMYNVRKGKM

PF00169 // ENSGT00440000037833_1_Domain_0 (654, 738)

QLPVNRW
TRRQVILCGTCLIVSSVKDSVSGKMHVLPLIGGKVEEVKKH-QHCLAFSSSGPQSQTYYI
CFDTFTEYLRWLRQVSKVASQRISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLRQTP
TLPAARGLGELQRF-TKLKSLNLSNNHLGAFPSAVCSI

PF13855 // ENSGT00440000037833_1_Domain_4 (819, 876)

PTLAELNVSCNALREIPAAVGD
MQNLQTFLLDGNFLQSLPAELESMHQLSYLGLSFNEFTDIPEVLEKLTAVEKLCMAGNCM
ETLRLQALRRMPHIKHVDLRLNILRKLMA-DEVDFV

PF13516 // ENSGT00440000037833_1_Domain_8 (937, 952)

QHVTQLDLRDNKLGDLDAMIFNNI
EVLH----------------------C----------------ERNQLVTLNVCGYF---
LKALYASSNELVQLDVYPVPNYLSYMDVSRNCLESVPEWVCESRKLEVLDIGHNQICELP
ARLFCNSSLRKLLAGHNRLARLPERLERTSVEVLDVQHNQIAELPPNLLMKADSLRFLNA
SANKLETLPPATLSEETSS---I

PF13855 // ENSGT00440000037833_1_Domain_15 (1164, 1279)

LQELYLTNNCL----------------------TDKC
VPLLTGHPRLKILHMAYNRLQSFPA-SKMAK-----------------------------
-----LEELEEIDISGNKLKAIPTTIMNCRRMHTVIAHSNCIEVFPEVMQLPEVKCVDLS
CNELSEITLPENLPPKLQELDLTGNPRLALDHKSLELLN-NIRCFKIDQPSAG----DAS
GAPAVWSH

PF00481 // ENSGT00440000037833_1_Domain_18 (1389, 1632)

GYTEASGVKNKLCVAALSVNNFRDNREALYGVFDGDRNVEVPYLLQCTMSDI
LAEELQKTKNEEEYMVNTFIVMQRKLGTAGQKLGGAAVLCHIKHDPVDLGGSFTLTSANV
GKCQTVLCRNGKPLSLSRSYIMSCEEERKRIKQHKAIVTED-GKVN--GVTES-TRILG-
YTFLHPSVVPRPHVQSVLLTPQDEFFILGSKGLWDSLSIDEAVEAVRNVPDALAAAKKLC
TLAQSYGCHDSISAVVVQLSVTEDSFCCCELSAGGSMPPPSPGIFPPSVNMVIKDRPSDG
LGVPSSSSGMASEISSELSTSEMSSEVGSTASDEPP-SGVLNE--SSPAYPNEQRCMLHP
VCLSNSFQRQLSS----ATFSSAFSDNGLDSDDEEPIEGVFSNGSRVE------VEVDIH
CSRAKEKERQQ-HLLQVPAEASDEGIVISANEDESGLSKK-ADFSAVGTIGRRRANGSVA
PQERSHNVIEVAADAPLRKPGGYFAAPAQPDPDDQFIIPPELEEEVKEIMKHHQEQQQQQ
QQQ--QLL--PPPPQPPQ----------PQPQPQRHFQMDHLPDCYDTPL

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-----------------LNCLFALV--PGKPHSTCSSER

PF00169 // ENSGT00440000037833_1_Domain_0 (640, 740)

IQLSGMYNVRKGKMQLPVNRW
TRRQVILCGTCLIVSSVKDSLTGKMHVLPLIGGKVEEVKKH-QHCLAFSSSGPQSQTYYI
CFDTFTEYLRWLRQVSKVA

ENSGT00440000037833_1_Linker_0_1 (740, 742)

SQ

PF00560 // ENSGT00440000037833_1_Domain_1 (742, 760)

RISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLRKQE
----PGSIDAFNRF-T

PF00560 // ENSGT00440000037833_1_Domain_3 (797, 818)

KLKSLNLSNNHLGDFPLAVCN

ENSGT00440000037833_1_Linker_3_5 (818, 820)

IP

PF00560 // ENSGT00440000037833_1_Domain_5 (820, 841)

TLTELNVSCNALRAVPAAVGV

ENSGT00440000037833_1_Linker_5_4 (841, 843)

MH

PF00560 // ENSGT00440000037833_1_Domain_4 (843, 864)

NLQTFLLDGNFLQSLPAELEN

ENSGT00440000037833_1_Linker_4_6 (864, 866)

MH

PF00560 // ENSGT00440000037833_1_Domain_6 (866, 887)

QLSYLGLSFNEFTDIPEVLEKLTAVDKLCMSGNCM
ETLRLQALRKMPHIKHVDLRLNIIKKLIA-DEVDFLQHVTQLDLRDNKLGDLDAMIFNNI
EVLH----------------------C----------------ERNQLVTLNICGYF---
LKALYASSNELVQLDVYPVPNYLFYMDVSRNCLENVPEWVCESR

PF00560 // ENSGT00440000037833_1_Domain_10 (1065, 1087)

KLEVLDIGHNQICELP
ARLFCN

ENSGT00440000037833_1_Linker_10_11 (1087, 1088)

S

PF00560 // ENSGT00440000037833_1_Domain_11 (1088, 1106)

SLRKLLAGHNQLTSLPER

ENSGT00440000037833_1_Linker_11_12 (1106, 1110)

LERT

PF00560 // ENSGT00440000037833_1_Domain_12 (1110, 1128)

SVEVLDVQHNQLLELPPN

ENSGT00440000037833_1_Linker_12_13 (1128, 1134)

LLMKAD

PF00560 // ENSGT00440000037833_1_Domain_13 (1134, 1156)

SLRFLNA
SANKLETLPAATLSEETSS---ILQELYLTNNNL----------------------TDKC
VPLLTGHP

PF00560 // ENSGT00440000037833_1_Domain_15 (1209, 1266)

HLKILHMAYNRLQSFPA-SKMAK-----------------------------
-----

ENSGT00440000037833_1_Linker_15_16 (1266, 1268)

LE

PF00560 // ENSGT00440000037833_1_Domain_16 (1268, 1289)

ELEEVDISGNKLKAIPTTITN

ENSGT00440000037833_1_Linker_16_17 (1289, 1336)

CRRMHTVIAHSNCIEVFPEVMQLPEIKCVDLS
CNELSEVTLPENLPP

PF00560 // ENSGT00440000037833_1_Domain_17 (1336, 1358)

KLQELDLTGNPRLALDHKTLEL

ENSGT00440000037833_1_Linker_17_18 (1358, 1386)

LN-NIRCFKIDQPSAG----DAS
GAPAV

PF00481 // ENSGT00440000037833_1_Domain_18 (1386, 1632)

WSHGYTEASGVKNKLCVAALSVNNFCDNREALYGVFDGDRNVEVPYLLQCTMSDI
LAEELQKTKNEEEYMVNTFVVMQRKLGTAGQKLGGAAVLCHIKHDPVDPGGSFTLTSANV
GKCQTVLCRNGKPLPLSRSYVMSCEEELRRIKQHKAIITED-GKVN--GVTES-TRILG-
YTFLHPSVVPRPHVQSVALTPQDEFFILGSKGLWDSLSIEEAVGAVRNVPDALSAAKKLC
TLAQSYGCRDSLSAVVVQLSVTEDSFCCCDLGAGGAGPPPSPGIFPPSVSMVIKDRPSDG
LGVPSSSSGMASEISSELSTSEMSSEVGSTASDEPP-PGALSE--SGPPYPSEQRCLLHP
ACLSSAFQRQLSS----ATFSSAFSDNGLDSDDEEPIEGVFSNGSRVE------VEVDIH
CGRAKDRDKQQ-HLLQVPAEASDEGIVISANEDEPGLPRK-ADFASMGTIGRRRANGSVA
PQERSHNVIEVATEAPLRKPGGYFAAPAQPDPEDQFIIPPELEEEVKEIMKHHQQQQP--
-------PA------------------QLPLQPPRQCPADPLPDYCDTPL

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-PAQPLPLPQTASSPQPQQKAPRAIDSPG-------GAVREGSCEERAAAPVAPGGLQ--
STPGRSGVTAEKAPPPP----PPPTLYVQLHGETTRRLEAEEKPLQIQNDYLFQLGFG--
ELWRVQE----EGMDSEIGCLIRFY--AGKPHSTGSSERIQLSGMYNVRKGKM

PF00169 // ENSGT00440000037833_1_Domain_0 (654, 738)

QLPVNRW
TRRQVILCGTCLIVSSVKDSLTGKMHVLPLIGGKVEEVKKH-QHCLAFSSSGPQSQTYYI
CFDTFTEYLRWLRQVSKVASQRISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLRQNP
SLPAARGLNELQRF-

PF13516 // ENSGT00440000037833_1_Domain_3 (796, 810)

TKLKSLNLSNNHLG

ENSGT00440000037833_1_Linker_3_4 (810, 819)

DFPLAVCSI

PF13855 // ENSGT00440000037833_1_Domain_4 (819, 876)

PTLAELNVSCNALRSVPAAVGV
MHNLQTFLLDGNFLQSLPAELENMKQLSYLGLSFNEFTDIPEVLEKLTAVDKLCMSGNCM
ETLRLQALRKMPHIKHVDLRLNVIRKLIA-DEVDFL

PF13516 // ENSGT00440000037833_1_Domain_8 (937, 952)

QHVTQLDLRDNKLGDLDAMIFNNI
EVLH----------------------C----------------ERNQLVTLDICGYF---
LKALYASSNELVQLDVYPVPNYLSYMDVSRNRLENVPEWVCESR

PF00560 // ENSGT00440000037833_1_Domain_10 (1065, 1086)

KLEVLDIGHNQICELP
ARLFCNSSLRKLLAGHNQLARLPERLERTSVEVLDVQHNQLLELPPNLLMKADSLRFLNA
SANKLESLPPATLSEETNS---I

PF13855 // ENSGT00440000037833_1_Domain_15 (1164, 1279)

LQELYLTNNSL----------------------TDKC
VPLLTGHPHLKILHMAYNRLQSFPA-SKMAK-----------------------------
-----LEELEEIDLSGNKLKAIPTTIMNCRRMHTVIAHSNCIEVFPEVMQLPEIKCVDLS
CNELSEVTLPENLPPKLQELDLTGNPRLVLDHKTLELLN-NIRCFKIDQPSTG----DAS
GAPAVWSH

PF00481 // ENSGT00440000037833_1_Domain_18 (1389, 1632)

GYTEASGVKNKLCVAALSVNNFCDNREALYGVFDGDRNVEVPYLLQCTMSDI
LAEELQKTKNEEEYMVNTFIVMQRKLGTAGQKLGGAAVLCHIKHDPVDPGGSFTLTSANV
GKCQTVLCRNGKPLPLSRSYIMSCEEELKRIKQHKAIITED-GKVN--GVTES-TRILG-
YTFLHPSVVPRPHVQSVLLTPQDEFFILGSKGLWDSLSVEEAVEAVRNVPDALAAAKKLC
TLAQSYGCHDSISAVVVQLSVTEDSFCCCELSASGAVPPPSPGIFPPSVNMVIKDRPSDG
LGVPSSSSGMASEISSELSTSEMSSEVGSTASDEPP-PGALSE--NSPAYPSEQRCMLHP
ICLSNSFQRQLSS----ATFSSAFSDNGLDSDDEEPIEGVFTNGSRVE------VEVDIH
CSRAKEKEKQQ-HLLQVPAEASDEGIVISANEDEPGLPRK-ADFSAVGTIGRRRANGSVA
PQERSHNVIEVATDAPLRKPGGYFAAPAQPDPDDQFIIPPELEEEVKEIMKHHQEQQQQQ
QQQQQPP---PP---P---------QL--QPQLPRHYQLDQLPDYYDTPL

MEPAAAAPAQRLADPT-GEDRAPAA-------------------AAAAEGGRSPDSVLSA
AAP-S--GNGGAAREEAPCEAP-RGLPGRAG-GTGRRRRRGV-PQPAAGGAAPVTAAG--
-GGANSLLLRRGRLKRNLSAAASSSSSP-------------SSASSAAGGLPASCSASAS
LCTRSLDRKTLLQKH-RQLLQLQPSDRDWVRHQLQRGCVHVFDRHMASSYLRPVLCTLDT
TAAEVAARLLQLGHK----GGGVVKVLGHGPPPAAA--PAASDQTPATELGRDVEPPP--
------SSST---VGAVRGPARAPPA-DLPLPGGAW-------------TRC---APRVN
PAPSDSSPGELFA-----GGPCSPSRAPRP----A------SDTESFSLSPSAE--SVSD
RLDPYSSGGGSSSSSEEL-EADP-------------ATVLTGPSGP-P-H-------HPV
RSSQPRPPSPKTSALLQ-PKAPTGVDGTG-------LVVGEGPGDDKAVAAAAPGVPLWT
--PGRIRETVQK-------TSSPPSLYVQLHGETTRRLEADEKPLQIQNDYLFQLGFG--
ELWRVQE----EGMDSEIGCLIRFY--AGKPHSTGSSERIQLSGMYNVRKGKM

PF00169 // ENSGT00440000037833_1_Domain_0 (654, 738)

QLPVNRW
TRRQVILCGTCLIVSSVKDSSSGKMHVLPLIGGKVEEVKKH-QHCLAFSSSGPQSQTYYI
CFDTFTEYLRWLRQVSKVASQRISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLRQNP
SLPAARGLGELQRF-TKLKSLNLSNNHLGAFPSAVCSI

PF13855 // ENSGT00440000037833_1_Domain_4 (819, 876)

PTLAELNVSCNALREVPAAVGA
MQNLQTFLLDGNFLQSLPAELENMHQLSYLGLSFNEFTDIPEVLEKLTAVDKLCMAGNCM
ETLRLQALRRMPHIKHVDLRLNILRKLIT-DEVDFL

PF13516 // ENSGT00440000037833_1_Domain_8 (937, 952)

QHVTQLDLRDNKLGDLDAMIFNNI
EVLH----------------------C----------------ERNQLVTLNICGYF---
LKALYASSNELVQLDVYPVPNYLSYMDVSRNCLESVPEWVCESR

PF00560 // ENSGT00440000037833_1_Domain_10 (1065, 1086)

KLEVLDIGHNQICELP
ARLFCNSSLRKLLAGHNRLARLPERLERTSVEVLDVQHNQIIELPPNLLMKADSLRFLNA
SANKLETLPPATLSEETSS---I

PF13855 // ENSGT00440000037833_1_Domain_15 (1164, 1279)

LQELYLTNNSL----------------------TDKC
VPLLTGHPRLKILHMAYNRLQSFPA-SKMAK-----------------------------
-----LEELEEIDISGNKLKAIPTTIMNCRRMHTVIAHSNCIEVFPEVMQLPEVKCVDLS
CNELSEITLPENLPPKLQELDLTGNPRLALDHKSLELLN-NIRCFKIDQPSAG----DAS
GAPAVWSH

PF00481 // ENSGT00440000037833_1_Domain_18 (1389, 1632)

GYTEASGVKNKLCVAALSVNNFRDNREALYGVFDGDRNVEVPYLLQCTMSDI
LAEELQKTKNEEEYMVNTFIVMQRKLGTAGQKLGGAAVLCHIRHDPVDLGGSFTLTSANV
GKCQTVLCRNGKPLSLSRSYTMSCEEERKRIKQHKAIITED-GKVN--GVTES-TRILG-
YTFLHPSVVPRPHVQSVLLTPQDEFFILGSKGLWDSLSIEEAVEAVRNVPDALAAAKKLC
TLAQSYGCHDSISAVVVQLSVTEDSFCCCELSVGGSMPPPSPGIFPPSVSMVIKDRPSDG
LGVPSSSSGMASEISSELSTSEMSSEVGSTASDEPP-SGALSE--SSPAYPSEQRCMLHP
VCLSNSFQRQLSS----ATFSSAFSDNGLDSDDEEPIEGVFSNGSRVE------VEVDIH
CSRAKEKERQQ-HLLQVPAEASDEGIVISANEDESGLSKK-TDISAVGTIGRRRANGSVA
PQERSHNVIEVATDAPLRKPGGYFAAPAQPDPDDQFIIPPELEEEVKEIMKHHQEQQQQQ
QQQQQQQQQQQQPPPPPQP-P--QAQAQAQAQAQRPFQMDHLPDCYDTPL

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-------------MDSEIGCLIRFY--AGKPHSSGSSERIQLSGMYNVRKGKMQLPVNRW
TRRQVILCGTCLIVSSVKDSLTGKMHVLPLIGGKVEEVKKH-QHCLAFSSSGPQSQTYYI
CFDTFTEYLRWLRQVSKVASQRISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLRQNP
CLPTARGLSELQRF-T

PF00560 // ENSGT00440000037833_1_Domain_3 (797, 814)

KLKSLNLSNNHLGDFPLAVCNIPTLTELNVSCNALRAVPAAVGV
MHNLQTFLLDGNFLQALPPELENMQQLSYLGLSFNEFTDIPEVLEKLTAVDKLCMSGNCM
ETLRLQALRKMPHIKHVDLRLNVIRRLVA-DEVDFLQHVTQLDLRDNKLGDLDAMIFNNI
EVLH----------------------C----------------ERNQLVTLNICGYF---
LKALYAASNELVQLDVYPVPSYLSYMDVSRNCLENVPEWVCESR

PF00560 // ENSGT00440000037833_1_Domain_10 (1065, 1081)

KLEVLDIGHNQICELP
AR----------------------------------------------------LRFLNA
SANKLETLPPATLSEETNS---ILQELYLTNNSL----------------------TDKC
VPLLTGHPHLKILHMAYNRLQSFPA-R---------------------------------
------------------------------------------------------------
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--------------------------------------------------

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-----------------------------------------------KAAAAALGGALLI
--PGRSKGTLEK-------GPLPPTLYMQLHGETTRRLEADEKPLQIQNDYLFQLGFG--
ELWRVQ-EE---GMDSEIGCLIRFY--AGKPHSTGSSERIQLSGMYNVRKGRM

PF00169 // ENSGT00440000037833_1_Domain_0 (654, 738)

QLPVNRW
TRRHVILCGTCLIVSSVKDSLTGKMHVLPLIGGKVEEVKKH-QHCLSFSSSGPQSQTYYI
CFDTFTEYLRWLRQVSKVASQRISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLRQNP
SLPAARGLNELQRF-

PF13516 // ENSGT00440000037833_1_Domain_3 (796, 810)

TKLKSLNLSNNHLGDFPLAVCSIPTLTELNMSCNALRAVPAAVGA
MHNLQTFLLDGNFLQSLPA--ENMHQLSYLGLSFNEFTDIPEVLEKLTAVDKLCMSGNCM
ETLRLQALRRMPHIKHVDLRLNIIRKLTA-DEVEFL

PF13516 // ENSGT00440000037833_1_Domain_8 (937, 952)

QHITQLDLRDNKLGD

ENSGT00440000037833_1_Linker_8_10 (952, 1063)

LDAMIFNNI
EVLH----------------------C----------------ERNQLVTLNICGYY---
LKALYAASNELVRLDVYPVPNYLSYMDVSRNHLENVPEWVCE

PF13516 // ENSGT00440000037833_1_Domain_10 (1063, 1078)

SRKLEVLDIGHNQICDLP
AHVFCNSSLRKLLAGHNQLARLPERLERTSVEVLDIQHNQLIELPPNLLLKADSLRFLNA
SANKLETLPPATLSEETNS---I

PF13855 // ENSGT00440000037833_1_Domain_15 (1164, 1279)

LQELYLTNNNL----------------------TDKC
VPLLTGHPHLKILHMAYNRLQSFPA-SKMAK-----------------------------
-----LEELEEIDISGNKLKAIPTTIMNCRRMHTVIAHSNSIEVFPEVMQLPEIKCVDLS
CNELSEVTLPENLPPKLQELDLTGNPRLALDHKTLELLN-NIRCFKIDQPSSG----DAS
GAPAVWSH

PF00481 // ENSGT00440000037833_1_Domain_18 (1389, 1632)

GYTEASGMKNKLCVAALSVNNFCDNREALYGVFDGDRNVEVPYLLQCTMSDI
LAEELQKTKNEEEYMVNTFIVMQRKLGTAGQKLGGAAVLCHIKHDPVDPGGSFTLTSANV
GKCQTVLCRNGKPLPLSRSYVMSCEEELKRIKQHKAIITED-GKVN--GVTES-TRILG-
YTFLHPSVVPRPHVQSVLLTPQDEFFILGSKGLWDSLSIEEAVEAVRNVPDALAAAKKLC
TLAQSYGCHDSISAVVVQLSVTEDSFCCCELSTGGSVPPPSPGIFPPSVNMVIKDRPSDG
LGVPSSSSGMASEISSELSTSEMSSEVGSTASDEPP-PGALNE--SSSAYPSEQRCTLHP
ICLSNSFQRQLSS----ATFSSAFSDNGLDSDDEEPIEGVFTNGSRVE------VEVDIH
CIRAKEKEKQQ-HLLQVPAEASDEGIVISANEDEPGLPRK-ADFSSVGTIGRRRANGSVA
PQERSHNVIEVAADAPLRKSGGYFAAPAQPDPDDQFIIPPELEEEVKEIMKHHQEQQ-QQ
PPQ------------IQ------------QQPLQRQFQMDQLPDYYDTPL

MEPAAAATVQRLPELGREDRASAPAAAAAAAAA--AAAAAAAALAAAAGGGRSPEPALTP
AAPSGGNGSGGGAREEAPGEAPPGPLPGRAG-GAGRRRRRGA-PQPIAGGAASVPGAGG-
--GANSLLLRRGRLKRNLSAAAAAASSS-----S-SSSAAAASHSPGAAGLPASCSASAS
LCTRSLDRKTLLLKH-RQTLQLQPSDRDWVRHQLQRGCVHVFDRHMASTYLRPVLCTLDT
TAGEVAARLLQLGHK----GGGVVKVLGQGPGAAAAREPAEP----PPEAGPRLAPPEPR
DSEVPPARSA---PGAVGGPPRAPPA-DLPLPVGGP-------------GGWSR---RAS
PAPSDSSPGEPFV-----GGPVSSPRAPRPVV---------SDTESFSLSPSAE--SVSD
RLDPYSSGGGSS-S-SEELEAD-------------AASAPTGVPGQ-PR--------RPG
HPAQPLPLPQTASSPQPQQKAPRAIDSPG-------GAVREGSCEERAAAAVAPGGLQ--
STPGRSGVTAEKAPPPP----PPPTLYVQLHGETTRRLEAEEKPLQIQNDYLFQLGFG--
ELWRVQE----EGMDSEIGCLIRFY--AGKPHSTGSSERIQLSGMYNVRKGKM

PF00169 // ENSGT00440000037833_1_Domain_0 (654, 738)

QLPVNRW
TRRQVILCGTCLIVSSVKDSLTGKMHVLPLIGGKVEEVKKH-QHCLAFSSSGPQSQTYYI
CFDTFTEYLRWLRQVSKVASQRISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLRQNP
SLPAARGLNELQRF-

PF13516 // ENSGT00440000037833_1_Domain_3 (796, 810)

TKLKSLNLSNNHLGDFPLAVCSIPTLAELNVSCNALRSVPAAVGV
MHNLQTFLLDGNFLQSLPAELENMKQLSYLGLSFNEFTDIPEVLEKLTAVDKLCMSGNCM
ETLRLQALRKMPHIKHVDLRLNVIRKLIA-DEVDFL

PF13516 // ENSGT00440000037833_1_Domain_8 (937, 952)

QHVTQLDLRDNKLGDLDAMIFNNI
EVLH----------------------C----------------ERNQLVTLDICGYF---
LKALYASSNELVQLDVYPVPNYLSYMDVSRNRLENVPEWVCESRKLEVLDIGHNQICELP
ARLFCNSSLRKLLAGHNQLARLPERLERTSVEVLDVQHNQLLELPPNLLMKADSLRFLNA
SANKLESLPPATLSEETNS---I

PF13855 // ENSGT00440000037833_1_Domain_15 (1164, 1279)

LQELYLTNNSL----------------------TDKC
VPLLTGHPHLKILHMAYNRLQSFPA-SKMAK-----------------------------
-----LEELEEIDLSGNKLKAIPTTIMNCRRMHTVIAHSNCIEVFPEVMQLPEIKCVDLS
CNELSEVTLPENLPPKLQELDLTGNPRLVLDHKTLELLN-NIRCFKIDQPSTG----DAS
GAPAVWSH

PF00481 // ENSGT00440000037833_1_Domain_18 (1389, 1632)

GYTEASGVKNKLCVAALSVNNFCDNREALYGVFDGDRNVEVPYLLQCTMSDI
LAEELQKTKNEEEYMVNTFIVMQRKLGTAGQKLGGAAVLCHIKHDPVDPGGSFTLTSANV
GKCQTVLCRNGKPLPLSRSYIMSCEEELKRIKQHKAIITED-GKVN--GVTES-TRILG-
YTFLHPSVVPRPHVQSVLLTPQDEFFILGSKGLWDSLSVEEAVEAVRNVPDALAAAKKLC
TLAQSYGCHDSISAVVVQLSVTEDSFCCCELSASGAVPPPSPGIFPPSVNMVIKDRPSDG
LGVPSSSSGMASEISSELSTSEMSSEVGSTASDEPP-PGALSE--NSPAYPSEQRCMLHP
ICLSNSFQRQLSS----ATFSSAFSDNGLDSDDEEPIEGVFTNGSRVE------VEVDIH
CSRAKEKEKQQ-HLLQVPAEASDEGIVISTNEDEPGLPRK-ADFSAVGTIGRRRANGSVA
PQERSHNVIEVATDAPLRKPGGYFAAPAQPDPDDQFIIPPELEEEVKEIMKHHQEQQQQ-
-QQQQPP---PP---P---------QL--QPQLPRHYQLDQLPDYYDTPL

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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------MDRECDCLVYYILPRGQPHDAGSSERIQLSGTFNVRKGKMQLPGSRW
ARRQVIMCGTCLIVSSVKDSLAGKMHVLPLIGGRVEEVKKHREHCLAFSSSGPQSQTYYV
CFDTFTEYLRWLRLASKVASQRISSVDLSCCSLEQLPANLFYSQDLTHLNLKQNFLRPGP
GPSVSRGLDELQRGSP

PF00560 // ENSGT00440000037833_1_Domain_3 (797, 814)

KLKSLNLSNNHLGDFPLAVCSIPTLVELNVSCNALRAVPAAVGD
MHNLQTFLLDGNHLLSLPAEMENMRQLGYLGLSFNEFADLPGVLARLTAVDRLCMSGNCL
ETLSLQALGRVPHIKHVDLRLNAIRELVVAGDSDALHHVTQLDLRDNKLVELDVTVFCNV
QVLH----------------------C----------------ERNQLGSLSLCGAS---
LKALYASSNELVHLDVCPVPNFLTLMDLSRNRLENVPEWVCDSP

PF00560 // ENSGT00440000037833_1_Domain_10 (1065, 1086)

KLEVLDVGHNRIRELP
ARLFCNRGLRKLLAGHNRLTRLPDRLEGTQVEVLDVQHNQLLELPPTLLLKADRYRPRAS
RAAGF---PRRGLPARPSPAPCLFPG-FHHPGALGLRASGAPGSRASGAVGFRTASSPHC
TLPLPCASGATSLPRRVLPGQSFPHPSHAARAAAPRAREK--------------------
----------------------------RRRAER--------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

--------------------------------------------------GKLQPPQC-T
ACPSATS--PRVRRETSWETAPPRPRTHASR-LFTLRPRL-----------------QAP
ALPAPPRNVVIGRLKRNLSAAAAAAASSS------------SSPSSAAAGLPASCSASAS
LCTRSLDRKTLLLKH-RQLLQLQPSDRDWVRHQLQRGCVHVFDRHMASSYLRPVLCTLDT
TAAEVAARLLQLGHK----GGGVVKVLGQGPPPAAAPAGSEQ----TPDAELRR------
-------------------------------------------------------DVEPP
PAPSDSSPGELFA-----GGPGSPPRAPHPA----------SDTESFSLSPSAE--SVSD
RLDPYSSGGGSSSSEELEADPAP---------------GSTGAPGP-PP-------LRPG
RPAQPRPP-SPKTSPPLQPKTPRGVDGTG-------GMAGQGPRECKVAA-AAPGGLPST
--PGRIRETAQ-------KTSSPPSLYVQFHGETTRRLEADEKPLQIQNDYLFQLGFG--
ELWRVQE----EGMDSEIGCLIRFY--AGKPHSTGSSERIQLSGMYNVRKGKM

PF00169 // ENSGT00440000037833_1_Domain_0 (654, 738)

QLPVNRW
TRRQVILCGTCLIVSSVKDSLSGKMHVLPLIGGKVEEVKKH-QHCLALSSSGPQSQTYYI
CFDTFTEYLRWLRQVSKVASQRISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLRQNP
TLSAARGLGELQRF-TKLKSLNLSNNHLGAFPSAVCSI

PF13855 // ENSGT00440000037833_1_Domain_4 (819, 876)

PTLTELNVSCNALREVPAAVGA
MQNLQTFLLDGNFLQSLPAELENMHQLSYLGLSFNEFTDIPEVLEKLTAVDKLCMAGNCM
ETLRLQALRRMPHIKHVDLRLNILRKLVA-DEVDFV

PF13516 // ENSGT00440000037833_1_Domain_8 (937, 954)

QHVTQLDLRDNKLGDLDAMVFNNI
EVLH----------------------C----------------ERNQLVTLNICGYF---
LKALYASSNELVQLDVYPVPNYLSSMDVSRNCLESVPEWVCESRKLEVLDIGHNQICELP
ARLFCNSSLRKLLAGHNQLARLPERLERTSVEVLDVQHNQLIELPPNLLMKADSLRFLNA
SANKLETLPPATLSEETSS---I

PF13855 // ENSGT00440000037833_1_Domain_15 (1164, 1279)

LQELYLTNNSL----------------------TDKC
VPLLTGHPRLKILHMAYNRLQSFPA-SKMAK-----------------------------
-----LEELEEIDISGNKLKAIPTTIMNCRRMHTVIAHSNCIEVFPEVMQLPEVKCVDLS
CNELSEITLPENLPPKLQELDLTGNPRLALDHKSLELLN-NIRCFRIDQPSAG----DAS
GAPAVWSH

PF00481 // ENSGT00440000037833_1_Domain_18 (1389, 1632)

GYTEASGVKNKLCVAALSVNNFRDNREALYGVFDGDRNVEVPYLLQCTMSDI
LAEELQKTKNEDEYMVNTFIVMQRKLGTAGQKLGGAAVLCHIKHDPVDLGGSFTLTSANV
GKCQTVLCRNGKPLPLSRSYVMSCEEELKRIKQHKAIITED-GKVN--GVTES-TRILG-
YTFLHPSVVPRPHVQSVLLTPQDEFFILGSKGLWDSLSIEEAVEAVRNVPDALAAAKKLC
TLAQSYGCHDSISAVVVQLSVTEDSFCCCELSAAGSMPPPSPGIFPPSVNMVIKDRPSDG
LGVPSSSSGMASEISSELSTSEMSSEVGSTASDEPP-SGVLSE--SSPAYPNEQRCMLHP
VCLSNSFQRQLSS----ATFSSAFSDNGLDSDDEEPIEGVFSNGSRVE------VEVDIH
CSRAKEKER-Q-HLLQVPAEASDEGIVISANEEESGLSKK-ADFSAVGTIGRRRANGSVA
PQERSHNMIEVAADAPLRKPGGYFAAPAQPDPDDQFIIPPELEEEVKEIMKHHQEQQQQQ
QQQPQPP---QPQPP------PQ------PAQPQRQFQVDHLPDCYDTPL

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------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------EADEKPLQIQNDYLFPLGFG--
ELWRVQE----EGMDSEIGCLIRFY--AGKPHSTGSLER

PF00169 // ENSGT00440000037833_1_Domain_0 (640, 740)

IQLSGMYNVRKGKMQLPVNRW
TRRQVILCGTCLIVSSVKDSVTGKMHVLPLIGGKVEEVKKH-QHCLAFSSSGPQSQTYYI
CFDTFTEYLRWLRQVSKVA

ENSGT00440000037833_1_Linker_0_1 (740, 742)

SQ

PF00560 // ENSGT00440000037833_1_Domain_1 (742, 760)

RISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLRQNP
SLPAARGLNELRRF-T

PF00560 // ENSGT00440000037833_1_Domain_3 (797, 818)

KLRSLNLSNNHLGDFPLAVCN

ENSGT00440000037833_1_Linker_3_5 (818, 820)

IP

PF00560 // ENSGT00440000037833_1_Domain_5 (820, 841)

TLTELNVSCNALRAVPAAVGV

ENSGT00440000037833_1_Linker_5_4 (841, 843)

MH

PF00560 // ENSGT00440000037833_1_Domain_4 (843, 864)

NLQTFLLDGNFLQSLPAELEN

ENSGT00440000037833_1_Linker_4_6 (864, 866)

MH

PF00560 // ENSGT00440000037833_1_Domain_6 (866, 887)

QLSYLGLSFNEFTDIPEVLEKLTAVDKLCMSGNCM
ETLRLQALRKMPHIKHVDLRLNLIRKLIA-DEVDFLQ

PF00560 // ENSGT00440000037833_1_Domain_8 (938, 960)

HITQLDLRDNKLGDLDATVFNNI
DVLH----------------------C----------------ERNQLVTLRVCGYF---
LKALYASSNELVQLDVYPFPNYLSYMDISRNRLENVPEWVCESR

PF00560 // ENSGT00440000037833_1_Domain_10 (1065, 1087)

KLEVLDIGHNQICELP
ARLFCN

ENSGT00440000037833_1_Linker_10_11 (1087, 1088)

S

PF00560 // ENSGT00440000037833_1_Domain_11 (1088, 1106)

SLRKLLAGHNQLTRLPERLERTLVEVLDVQHNQLLELPPNLLMKAD

PF00560 // ENSGT00440000037833_1_Domain_13 (1134, 1156)

SLRFLNA
SANKLETLPPATLSEETRS---ILQELYVTNNSL----------------------TDKC
VPLLTGHP

PF00560 // ENSGT00440000037833_1_Domain_15 (1209, 1266)

HLKILHMAYNRLQSFPA-SKMAK-----------------------------
-----

ENSGT00440000037833_1_Linker_15_16 (1266, 1268)

LE

PF00560 // ENSGT00440000037833_1_Domain_16 (1268, 1289)

ELEEVDVSGNKLKAIPTTIMNCRRMHTVIAHSNCIEVFPEVMQLPEIKXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-NIRCFKIDQPSAG----DAS
GAPAV

PF00481 // ENSGT00440000037833_1_Domain_18 (1386, 1632)

WSHGYTEVSGVKNKLCVAALSVNNFCDNREALYGVFDGDRNVEVPNLLQCTMSDI
LAEELQKTKHEEEYMINTFIVMQRKLGTAGQKLGGAAVLCHIKHDPVDPGGSFTLTSANV
GKCQTVLCRNGKPLPLSRSYSMSCEEELKRIRQHKAIITED-GKVN--GVTES-TRILG-
YTFLHPSVVPRPHVQSVTLTPQDEFFILGSKGLWDSLSIEEAVEAVRNVPDSLAAAKKLC
TLAQSYGCHDSISAVVVQLNVTEDSFCCCDLSAGSTVPPPSPGIFPPSVNMVIKDRPPDG
LGVPSSSSGMASEISSEISTSEMSSEVGSTASDEPP-AGALNE--SSPACPSEQRCMLHP
VCLSNSFQRQLSS----ATFSSAFSDNGLDSDDEEPIEGVFTNGSRVE------VEVDIH
CNRAKEKERQQ-GLLQVPAEASDEGIVISANEDEPGLPRK-ADFSAVGTIGRRRANGSVA
PQERSHNVIEVATDAPLRKPGGYFAAPAQPDPDDQFIIPPELEEEVKEIMKHHQEQQQQQ
QQQQQQQPQ------------------LQQQLPQRQYPMDQLPDYYDTPL

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------------------------------------------------SRQQSPAPSASR
GPPVISFPV--SSP--SSSSPL----S------------PLSSSSSSSSSSSSS--SSSS
SSSSSSSSSSS--------SSSSSSSSSSSSSSSSSSSSS-------------SS-----
----SSSSSSSPLPPPPSPSSPQFCLAEHSQRIMFPSLCLTGSIS-RLSFQVVPWQTACC
PGRTGIFANKV------PPPPPPPTLYVQFHGETTRRLEAHEKPLQIQNDYLFQLGFR--
ELWRVQE----EGMDSEIGCLIRFY--AGKPHSTGSSERIQLSGMYNVRKGKMQLPVNRW
TRRQVILCGTCLIVSSVKDSLTGKMHVLPLIGGKVEEVKKH-QHCLAFSSSGPQSQTYYI
CFDTFTEYLRWLRQVSKVASQRISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLRQNP
SSPSSRGLGELKRF-T

PF00560 // ENSGT00440000037833_1_Domain_3 (797, 814)

KLKSLNLSNNHLGDFPLAVCNIPTLTELNMSCNALRTVPATAGD
MHNLQTFLLDGNYLQSLPAELENMQQLSYLGLSFNEFTDIPKVLEKLTAVDKLCMSGNCM
EILNLQTLRKMPHIKHVDLRLNVIRKLMV-QEVDFLPHVTQLDLRDNKLEDLDSTVFNNI
EVLH----------------------C----------------ERNQLVTLNVCGYL---
LKALYASSNELVQLDVYPVPNHLTFMDVSRNHLESVPEWVCESR

PF00560 // ENSGT00440000037833_1_Domain_10 (1065, 1085)

KLEVLDIGHNQIRELP
ARLFYNSSLRKLLVGHNQLTRLPERLERTQVEVLDVQHNQLVELPPNLLMKADSLRFLNA
SANKLETIPPATLSEETSS---ILQELYLTNNHL----------------------TDKC
VPLLIGHPHLKILHMAYNRLQSFPA-SKMAK-----------------------------
-----LEELEEIDISGNKLKAIPTTIMNCRRMHTVIAHSNCIEVFPEVMQLTEIKCVDLS
CNELSEVTLPENLPSKLQELDLTGNPRLALDHKTLELLN-NIRCFKIDQPSAG----DAS
GAPAVWSHG

PF00481 // ENSGT00440000037833_1_Domain_18 (1390, 1632)

YTEASGVKNKLCVAALSANNFCDNREALYGVFDGDRNVEVPYLLQCTMSDI
LAEELQKTKNEEEYMVNTFIVMQRKLGTAGQKLGGSAVLCHIKHDPMDPGGYFTLTSANV
GKCQTVLCRNGKPLPLSKSYIMSCEEELKRIKQHKAIITED-GKVN--GVTES-TRILG-
YTFLHPSVVPRPHVQSVTLTPQDEFFILGSKGLWDSLSIEEAVEAVRNVPDALAAAKKLC
TLAQSYGCNDSISAVVVQLNVTEDSFCCCELGAG-GVPPPSPGIFPPSVNVVIKDRPPDG
LGVPSSSSGMASEISSEISTSEMSSEVGSTASDEPP-PGTLSE--SGPGYPGEQRCMLHP
VCLSSAFQRQLSS----ATFSSAFSDNGLDSDDEEPIEGVFTNGSRVE------VEVDIH
CGQAKEKERQRQQPLQVPAEASDEGIVISANEDEAGPPRK-PDFSATGTIGRRRGNGSVA
PQERSHNVIEVAADAPLRKTGGYFAAPAQPDPDDQFIIPPELEEEVKEIMKHHQEQQQQQ
QQQQ---QQ------------------QQQQQQHRQYQMDQLPDYYDTPL

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------------------------------------------------------------
------------------------------------------------HSFWFQIGYN--
KMGQSQE----SGLKKEIKLLAVSI--SGKPHSIGNSERIQLSGMYNVRKGKMHLPVNRW
TRRQVILCGTCLIVSSVKESQTGKMHVLPLIGGKVEEVKKH-QHCLAFSSSGPQSQSYYI
CFDTFTEYLRWLRQASKIASQRISSVDLSCCSLEDLPANLFYSQDLTHLNLKQNFLRLNP
NSSSSRGLNELQRF-S

PF00560 // ENSGT00440000037833_1_Domain_3 (797, 814)

KLRSLNLSNNHLGEFPLAVCSIPTLTELNVSCNALKNIPVAVGD
MNNLQTFLLDGNFLQSLPVELERMHQLSYLGLSFNEFTDIPEILEKLPAMDKLCMSGNCL
ETLNLQTLRRMPHIKHIDLRLNVIRRLVT-DKADFLHHVTQLDLRDNKLGELDATIFNNV
EILH----------------------C----------------ERNQLVTLKISGYL---
LKALYATANELVHLDVYPVPNYLTYMDVSRNHLESLPEWVCDSR

PF00560 // ENSGT00440000037833_1_Domain_10 (1065, 1086)

KLEVLDLGHNQIRELP
ARLFCNISLRKLLAGHNQLARLPERIERTHVEVLDVQHNLLTELPSNLLLKADSLRYLNA
SANKLEMLPPATLSEETCS---ILQELYLTNNHL----------------------TDKC
VPLLTGHPHLKILHMAYNRLQSFPA-SKMAK-----------------------------
-----LEE

PF00560 // ENSGT00440000037833_1_Domain_16 (1269, 1288)

LEEIDVSGNKLKSIPTTIMNCRRMHTVIAHSNCIEVFPEVMQLGEIKCVDLS
CNELTEVTLPENLPPKLQELDLTGNPRLVLDHKTLELLN-NIRCFKIDQPSAG----DAS
GAPAVWSHG

PF00481 // ENSGT00440000037833_1_Domain_18 (1390, 1631)

YTEASGVKNKLCVAALSANNFCENREALYGVFDGDRNVEVPYLLQCTMSDI
LAEELQKTKSEEEYMINTFIVMQRKLGTAGQKLGGSAVLCHIKHDPIDPGGCFTLTSANV
GKCQSVLCRNGKPLPLSRSYMISCEEELRRIKQHKAIITED-GKVN--GVTDS-TRILG-
YTFLHPSVIPRPHVQSITLTPQDEFFILGSKGLWDSLSIEEAVEAVRNVPDALGAAKKLC
TLAQSYGCNDSLSAVVVQLNVTEDSFCCCELN---GVPPPSPGIFPQSVNVVIKDKPSDG
LGMPSSSSGVASEISSEISTSEMSSEVGSTASDEPP-QVTMNE--NSPAYPSEQRCMLHP
VCLSNSFQRQLSS----ATFSSAFSDNGLDSDDEEPIEGVFSNGSRVE------VEVDIH
CGRAKEKQ---QLLTQAPMEASDEGIVINTNEDEVCLLRK-GDLSATGTIGRRRGNGSVA
PQERSHNLIEVAADAPLRKTGGYFAAPAQPDPDDQFIIPPELEEEVKEIIIMTRHYDQAS
QNK--------------------------VMRQ-----------------

MEPAAAAPAQRLADPTGEDQALAA--------------------AAAAEGGRSPDPALSS
VAPSGGN--GGAAREEAPCEAPPGPLPGRAG-GTGRRRRRGA-PQPAAGGAAPVPAAGG-
--GANSLLLKRGRLKRNLSAAAAASSSSSP-----------SSASSAAGGLPASCSASAS
LCTRSLDRKTLLLKH-RQLLQLQPSDRDWVRHQLQRGCVHVFDRHMASSYLRPVLCTLDT
TAAEVAARLLQLGHK----GGGVVKVLGHGPPPAAAPAASDQ----TPDRELG------T
DVEPPPSSST---VGAVRGPARAPPA-DLPLPGG----------------AWTRCAPRVS
PAPSDSSPGELFA-----GGPGSPPRAPRPA----------SDAESFSLSPSAE--SVSD
RLDPYSSGGGGSSSSSEELETDPA-----------M-------------------PHRPG
RPAQP-RPPSPKTSALLQPKAPTGVDGTG-------AMAGEGPRDDKVVAAAAPDGPLST
--PGRIRETGQ-------KT-SPPSLYVQLHGETTRRLEADEKPLQIQNDYLFQLGFG--
ELWRVQE----EGMDSEIGCLIRFY--AGKPHSTGSSERIQLSGMYNVRKGKM

PF00169 // ENSGT00440000037833_1_Domain_0 (654, 738)

QLPVNRW
TRRQVILCGTCLIVSSVKDSVSGKMHVLPLIGGKVEEVKKH-QHCLAFSSSGPQSQTYYI
CFDTFTEYLRWLRQVSKVASQRISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLRQSP
TLPAARGLGELQRF-TKLRSLNLSNNHLGAFPSAVCSIPTLAELNVSCNALREVPAAVGD
MQNLQTFLLDGNFLQSLPAELESMQQLSYLGLSFNEFTDIPEVLEKLTAVDKLCMAGNCI
ETLRLQALRRMPHIKHVDLRLNILRKLMA-DEVDFV

PF13516 // ENSGT00440000037833_1_Domain_8 (937, 952)

QHVTQLDLRDNKLGDLDAMIFNNI
EVLH----------------------C----------------ERNQLVTLNVCGYF---
LKALYASSNELVQLDVYPVPNYLSYMDVSRNCLESVPEWVCESRKLEVLDIGHNQICELP
ARLFCNSSLRKLLAGHNRLARLPERLERTSVEVLDVQHNQITELPPNLLMKADSLRFLNA
SANKLETLPPATLSEETSS---I

PF13855 // ENSGT00440000037833_1_Domain_15 (1164, 1279)

LQELYLTNNCL----------------------TDKC
VPLLTGHPRLKILHMAYNRLQSFPA-SKMAK-----------------------------
-----LEELEEIDISGNKLKAIPTTIMNCRRMHTVIAHSNCIEVFPEVMQLPEVKCVDLS
CNELSEITLPENLPPKLQELDLTGNPRLALDHKSLELLN-NIRCFKIDQPSAG----DAS
GAPAVWSH

PF00481 // ENSGT00440000037833_1_Domain_18 (1389, 1632)

GYTEASGVKNKLCVAALSVNNFRDNREALYGVFDGDRNVEVPYLLQCTMSDI
LAEELQKTKNEEEYMVNTFIVMQRKLGTAGQKLGGAAVLCHIKHDPVDLGGSFTLTSANV
GKCQTVLCRNGKPLSLSRSYIMSCEEERKRIKQHKAIITED-GKVN--GVTES-TRILG-
YTFLHPSVVPRPHVQSVLLTPQDEFFILGSKGLWDSLSIDEAVEAVRNVPDALAAAKKLC
TLAQSYGCHDSISAVVVQLSVTEDSFCCCELSAGGSMPPPSPGIFPPSVNMVIKDRPSDG
LGVPSSSSGMASEISSELSTSEMSSEVGSTASDEPP-SGVLNE--SSPAYPNEQRCMLHP
VCLSNSFQRQLSS----ATFSSAFSDNGLDSDDEEPIEGVFSNGSRVE------VEVDIH
CSRAKEKERQQ-HLLQVPAEASDEGIVISANEDESGLSKK-ADFSAVGTIGRRRANGSVA
PQERSHNVIEVATDAPLRKPGGYFAAPAQPDPDDQFIIPPELEEEVKEIMKHHQEQQQQQ
QQQQQLLL--PTPPQPPQ----------PQSQPQRHFQMDHLPDCYDTPL

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------------PSEPQ
DLEPQPARSA---LAAVGGPPRAPPA-DLPLPGDDR-------------GGWARCASRVS
PAPSDSSPGEPFA-----RGPTSPPGTPRPLDGAAAG--PASDTESFSLSPSAE--SVSD
RLDPYSSGGGGGSSSSDELEADPA-----------P----AGAPSQ-LRRL---------
------GRPSPGSPPGPQQKAPRGVDGPG-------GVARDGPWGEKAAVTAALGGPM--
SIPGRSGVAAEKAPPPP----PPPTLYVQLHGETTRRLEADEKPLQIQNDYLFQLGFG--
ELWRVQE----EGMDSEIGCLIRFY--AGKPHSIGSSERIQLSGMYNVRKGKMQLPVNRW
TRRQVILCGTCLIVSSVKDSLTGKMHVLPLIGGKVEEVKKH-QHCLAFSSSGPQSQTYYI
CFDTFTEYLRWLRQVSKVASQRISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLRQNP
SLPAARGLNELQRF-T

PF00560 // ENSGT00440000037833_1_Domain_3 (797, 814)

KLKSLNLSNNHLGDFPLAVCSIPTLAELNVSCNALRAVPAAVGA
MHNLQTFLLDGNFLQSLPAELENMHQLSYLGLSFNEFTDIPEVLEKLTAVDKLCMSGNCM
ETLRLQALRKMPHIKHVDLRLNTIRKLIA-DEVDFLQHVTQLDLRDNKLGDLDAMIFNNI
EVLH----------------------C----------------ERNQLVTLNICGYF---
LKALYASSNELVQLDVYPVPNYLSYMDVSRNRLENVPEWVCESR

PF00560 // ENSGT00440000037833_1_Domain_10 (1065, 1086)

KLEVLDISHNEICELP
ARLFCNSSLRKLLAGHNQLARLPERLERTSVEVLDVQHNQILELPPNLLMKADSLRFLNA
SANKLETLPPATLCEETNS---ILQELYLTNNSL----------------------TDKC
VPLLTGHPHLKILHMAYNRLQSFPA-SKMAK-----------------------------
-----LEELEEIDISGNKLKAIPTTIMNCRRMHTVIAHSNCIEVFPEVMQLPEIKCVDLS
CNELSEVTLPENLPPKLQELDLTGNPRLVLDHKTLELLN-NIRCFKIDQPSAG----DTS
GAPAVWSH

PF00481 // ENSGT00440000037833_1_Domain_18 (1389, 1632)

GYTEASGVKNKLCVAALSVNNFCDNREALYGVFDGDRNVEVPYLLQCTMSDI
LAEELQKTKNEEEYMVNTFIVMQRKLGTAGQKLGGAAVLCHIKHDPVDPGGSFTLTSANV
GKCQSVLCRNGKPLPLSRSYVMSCEEELKRIKQHKAIITED-GKVN--GVTES-TRILG-
YTFLHPSVVPRPHVQSVLLTPRDEFFILGSKGLWDSLSIEEAVEAVRNVPDALAAAKKLC
TLAQSYGCHDSISAVVVQLSVTEDSFCCCELSASGTVPPPSPGIFPPSVNMVIKDRPSDG
LGVPSSSSGMASEISSELSTSEMSSEVGSTASDEPP-PGALNE--SSPACPSEQRCMLHP
LCLSNSFQRQLSS----ATFSSAFSDNGLDSDDEEPIEGVFTNGSRVE------VEVDIH
CSRAKEREKQQ-HLLQVPAEASDEGIVISANEDEPGLPRK-ADFSAVGTIGRRRPNGSVA
PQERSHNVIEVAADAPLRKPGGYFAAPAQPDPDDQFIIPPELEEEVKEIMKHHQEQQQPQ
P------------------------QL--QPPPQRHYQVDQLPDCYDTPL

MEPAAAATAQRLPEPGREDRASAPAAAAAAAAA---AAAAAAALAAAAGGGRSPEPALTP
AAPSGGNGSGGGAREEAPGEAPPGPLPGRAG-GAGRRRRRGA-PQPIAGGAAPVPGAGS-
--GANSLLLRRGRLKRNLSAAAAAASSS------SSSSAAAASHSPGAAGLPASCSASAS
LCTRSLDRKTLLLKH-RQTLQLQPSDRDWVRHQLQRGCVHVFDRHMASTYLRPVLCTLDT
TAGEVAARLLQLGHK----GSGVVKVLGQGPGAAAAREPAEP----PPEAGPRLAPPEPR
DSEALPARSA---PGAVGGPPRAPPA-DLPLPAAVP-------------GGWSR---RAS
PAPSDSSPGEPFV-----GGPASSPRAPRPVA---------SDTESFSLSPSAE--SVSD
RLDPYSSGGG-SS-SSEEVEADA-------------ASAPTGVPGQ-PR--------RPG
RSAQPLPPPQTASSPRPQQKAPRAVDSPG-------GAVREGPCEEKAAAFVASGGLQST
--PGRSGVTAEKAAPPP----PPPTLYVQLHGETTRRLEAEEKPLQIQNDYLFQLGFG--
ELWRVQE----EGMDSEIGCLIRFY--AGKPHSTGSSERIQLSGMYNVRKGKM

PF00169 // ENSGT00440000037833_1_Domain_0 (654, 738)

QLPVNRW
TRRQVILCGTCLIVSSVKDSLTGKMHVLPLIGGKVEEVKKH-QHCLAFSSSGPQSQTYYI
CFDTFTEYLRWLRQVSKVASQRISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLRQNP
SLPAARGLNELQRF-

PF13516 // ENSGT00440000037833_1_Domain_3 (796, 810)

TKLKSLNLSNNHLG

ENSGT00440000037833_1_Linker_3_4 (810, 819)

DFPLAVCSI

PF13855 // ENSGT00440000037833_1_Domain_4 (819, 876)

PTLAELNVSCNALRSVPAAVGV
MHNLQTFLLDGNFLQTLPAELENMKQLSYLGLSFNEFTDIPEVLEKLTAVDKLCMSGNCM
ETLRLQSLRKMPHIKHVDLRLNIIRKLIA-DEVDFL

PF13516 // ENSGT00440000037833_1_Domain_8 (937, 952)

QHVTQLDLRDNKLGDLDAMIFNNI
EVLH----------------------C----------------ERNQLVTLDICGYF---
LKALYASSNELVQLDVYPVPNYLSYMDVSRNRLENVPEWVCESRKLEVLDIGHNQICELP
ARLFCNSSLRKLLAGHNQLARLPERLERTSVEVLDVQHNQLLELPPNLLMKADSLRFLNA
SANKLESLPPATLSEETNS---I

PF13855 // ENSGT00440000037833_1_Domain_15 (1164, 1279)

LQELYLTNNSL----------------------TDKC
VPLLTGHPHLKILHMAYNRLQSFPA-SKMAK-----------------------------
-----LEELEEIDLSGNKLKAIPTTIMNCRRVHTVIAHSNCIEVFPEVMQLPEIKCVDLS
CNELSEVTLPENLPPKLQELDLTGNPRLVLDHKTLELLN-NIRCFKIDQPSTG----DAS
GAPAVWSH

PF00481 // ENSGT00440000037833_1_Domain_18 (1389, 1632)

GYTEASGVKNKLCVAALSVNNFCDNREALYGVFDGDRNVEVPYLLQCTMSDI
LAEELQKTKNEEEYMVNTFIVMQRKLGTAGQKLGGAAVLCHIKHDPVDPGGSFTLTSANV
GKCQTVLCRNGKPLPLSRSYIMSCEEELKRIKQHKAIITED-GKVN--GVTES-TRILG-
YTFLHPSVVPRPHVQSVLLTPQDEFFILGSKGLWDSLSLEEAVEAVRNVPDALAAAKKLC
TLAQSYGCHDSISAVVVQLSVTEDSFCCCELSAGGAVPPPSPGIFPPSVNMVIKDRPSDG
LGVPSSSSGMASEISSELSTSEMSSEVGSTASDEPP-PGALSE--NSPAYPSEQRCMLHP
VCLSNSFQRQLSS----ATFSSAFSDNGLDSDDEEPIEGVFTNGSRVE------VEVDIH
CSRAKEKEKQQ-HLLQVPAEASDEGIVISANEDEPGLPRK-ADFSAVGTIGRRRANGSVA
PQERSHNMIEVATDAPLRKPGGYFAAPAQPDPDDQFIIPPELEEEVKEIMKHHQEQQ---
QQQQ-PP---PP---P---------QL--QPQLPRHYQLDQLPDYYDTPL

MEPAAAATAQRLPEPGREDRASAPAAAAAAAAAAAAAAAAAAALAAAAGGGRSPEPALTP
AAPSGGNGSGGGAREEAPGEAPPGPLPGRAG-GAGRRRRRGA-PQPIAGGAAPVPGAGS-
--GANSLLLRRGRLKRNLSAAAAAASSSSS--SSSSSSAAAASHSPGAAGLPASCSASAS
LCTRSLDRKTLLLKH-RQTLQLQPSDRDWVRHQLQRGCVHVFDRHMASTYLRPVLCTLDT
TAGEVAARLLQLGHK----GGGVVKVLGQGPGAAAAREPAEP----TPEAGPRLAPPEPR
DSEALPARSA---PGAVGGPPRAPPA-DLPLPAGVP-------------GGWSR---RAS
PAPSDSSPGEPFV-----GGPASSPRAPRPVA---------SDTESFSLSPSAE--SVSD
RLDPYSSGGG-SS-SSEEVEADA-------------ASAPTGVPGQ-PR--------RPG
RSAQPLPPPQTASSPRPQQKAPRAVDSPG-------GAVREGPCEEKAAAFVASGGLQST
--PGRSGVTAEKAAPPP----PPPTLYVQLHGETTRRLEAEEKPLQIQNDYLFQLGFG--
ELWRVQE----EGMDSEIGCLIRFY--AGKPHSTGSSERIQLSGMYNVRKGKM

PF00169 // ENSGT00440000037833_1_Domain_0 (654, 738)

QLPVNRW
TRRQVILCGTCLIVSSVKDSLTGKMHVLPLIGGKVEEVKKH-QHCLAFSSSGPQSQTYYI
CFDTFTEYLRWLRQVSKVASQRISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLRQNP
SLPAARGLNELQRF-

PF13516 // ENSGT00440000037833_1_Domain_3 (796, 810)

TKLKSLNLSNNHLG

ENSGT00440000037833_1_Linker_3_4 (810, 819)

DFPLAVCSI

PF13855 // ENSGT00440000037833_1_Domain_4 (819, 876)

PTLAELNVSCNALRSVPAAVGV
MHNLQTFLLDGNFLQTLPAELENMKQLSYLGLSFNEFTDIPEVLEKLTAVDKLCMSGNCM
ETLRLQALRKMPHIKHVDLRLNIIRKLIA-DEVDFL

PF13516 // ENSGT00440000037833_1_Domain_8 (937, 952)

QHVTQLDLRDNKLGDLDAMIFNNI
EVLH----------------------C----------------ERNQLVTLDICGYF---
LKALYASSNELVQLDVYPVPNYLSYMDVSRNRLENVPEWVCESRKLEVLDIGHNQICELP
ARLFCNSSLRKLLAGHNQLARLPERLERTSVEVLDVQHNQLLELPPNLLMKADSLRFLNA
SANKLESLPPATLSEETNS---I

PF13855 // ENSGT00440000037833_1_Domain_15 (1164, 1279)

LQELYLTNNSL----------------------TDKC
VPLLTGHPHLKILHMAYNRLQSFPA-SKMAK-----------------------------
-----LEELEEIDLSGNKLKAIPTTIMNCRRVHTVIAHSNCIEVFPEVMQLPEIKCVDLS
CNELSEVTLPENLPPKLQELDLTGNPRLVLDHKTLELLN-NIRCFKIDQPSTG----DAS
GAPAVWSH

PF00481 // ENSGT00440000037833_1_Domain_18 (1389, 1632)

GYTEASGVKNKLCVAALSVNNFCDNREALYGVFDGDRNVEVPYLLQCTMSDI
LAEELQKTKNEEEYMVNTFIVMQRKLGTAGQKLGGAAVLCHIKHDPVDPGGSFTLTSANV
GKCQTVLCRNGKPLPLSRSYIMSCEEELKRIKQHKAIITED-GKVN--GVTES-TRILG-
YTFLHPSVVPRPHVQSVLLTPQDEFFILGSKGLWDSLSLEEAVEAVRNVPDALAAAKKLC
TLAQSYGCHDSISAVVVQLSVTEDNFCCCELSAGGAVPPPSPGIFPPSVNMVIKDRPSDG
LGVPSSSSGMASEISSELSTSEMSSEVGSTASDEPP-PGALSE--NSPAYPSEQRCMLHP
VCLSNSFQRQLSS----ATFSSAFSDNGLDSDDEEPIEGVFTNGSRVE------VEVDIH
CSRAKEKEKQQ-HLLQVPAEASDEGIVISANEDEPGLPRK-ADFSAVGTIGRRRANGSVA
PQERSHNMIEVATDAPLRKPGGYFAAPAQPDPDDQFIIPPELEEEVKEIMKHHQEQQ---
QQQQ-PP---PP---P---------QL--QPQLPRHYQLDQLPDYYDTPL

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------PDTSLIISFY--LCKPHSTGSSERIQLSGMYNVRKGKIHLPVNRW
TRRQAILCGTCLIVSSVKESQTGKMHVLPLIGGKVEEVKKH-QHCLAFSSSGPQSQTYYI
CFDNFTEYLRWLRQASKVASQRISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLRLNP
SPSTSRALSELQRF-T

PF00560 // ENSGT00440000037833_1_Domain_3 (797, 814)

KLKSLNLSNNNLGEFPLAVCSIPTLTELNVSCNALRSIPAVVGE
MHNLQTFLLDGNFLQSLPDELEHMHQLSYVSLSFNEFTDIPGVLEKLTAMDKLCMSGNCI
DTLNLQVLKRMPHIKHVDLRLNSIRRLEA-DEIDFLHHVTQLDLRDNKLGELDATVFNNV
EVLH----------------------C----------------ERNQLVTLKISGYF---
LKALYASCNELVHLDVYPVPNCLAYMDISRNHLENLPEWVCDSR

PF00560 // ENSGT00440000037833_1_Domain_10 (1065, 1085)

KLEVLDVGHNQIRELP
ARLFYNSSLRKLLAGHNMLGRLPDRLERTQVEVLDVQHNQLLELPPNLLLKADSLRFLNA
SANKLEMLPPATLSEETHS---ILQELYLTNNNL----------------------TDKC
VPLLTGHPHLKILHMAYNRLQSFPA-SKMAK-----------------------------
-----LEELEEIDISGNKLKAIPTTIMNCRRMHTVIAHSNCIEVFPEVMQLSEIKCVDLS
CNELSEVTLPENLPPKLQELDLTGNPRLALDHKTLELLN-NIRCFKIDQPSAG----DAS
GAPAVWSHG

PF00481 // ENSGT00440000037833_1_Domain_18 (1390, 1632)

YTEASGVKNKLCVAALSANNFCDNREALYGVFDGDRNVEVPYLLQCTMSDI
LAEELQKTKNEEEYMINTFIVMQRKLGTAGQKLGGSAVLCHIKHDPMDPGGCFTLTSANV
GKCQTVLCRNGKPLPLSRCYVMSCEEELKRIKQHKAIITED-GKVN--GVTDS-TRILG-
YTFLHPSVVPRPHVQSITLTPQDEFFILGSKGLWDSLSMDEAVEAVRNVPDALAAAKKLC
TLAQSYGCNDSISAVVVQLNVTEDSFCCCELN---GVPPPSPGIFPQSVNVVIKDRPADA
LGMPSSSSGMASEISSEISTSEMSSEVGSTASDEPP-QVAMNE--SSPAYPGEQRCMLHP
VCLANSFQRQLSS----ATFSSAFSDNGLDSDDEEPIEGVFTNGSRVE------VEVDIH
CSRAKDKQ---L--LQVPVEASDEGIVISANEDEPSLPRK-AEYCATGTIGRRRGNGSVA
PHERSHNLIEVATDAPLRKTGGYFAAPAQPDPDDQFIIPPELEEEVKEIMKQHQEQQQQQ
--Q--------------------------QQQQQRQYPMDHLADYYDTPL

MEPAAGAPAQRLADPA-GEDRAPAA----------------A---AAAEGARSPAPALSL
AAASG--GNGGAAREQAPCEAPPGPMPGRAG-GTGRRRRRGA-PQSAAGGAIPVPAAGG-
-GGANSLLLRRGRLKRNLSAAASASSLP-------------SSASSAAGGLPASCSASAS
LCTRSLDRKTLLLKH-RQLLQLQPSDRDWVRHQLQRGCVHVFDRHMASSYLRPVLCTLDT
TAAEVATRLLQLGHK----GGGVVKVLGQGPPPAAAAAPAGSDQTPDAGLGRDVEPPP--
------SSGT---LGAVGGPARAPPA-DLPLPGGAW-------------TPC---APRAS
PAPSDSSPGELFA-----GGPGSPPRAPHP----A------SDTESFSLSPSAE--SVSD
RLDPYSSGGGSSS-SEEL-EADP-------------ALVSTGALGP-PPL-------RPG
RPAQPQPPSAKTS-PSLQPKAPRGVDGTG-------GMASQGPKEDKAVAAAAPAGPLST
--PGRIRETAQK-------TTSPPSLYVQFHGETTRRLEADEKPLQIQNDYLFQLGFG--
ELWRVQE----EGMDSEIGCLIRFY--AGKPHSTGSSERIQLSGMYNVRKGKM

PF00169 // ENSGT00440000037833_1_Domain_0 (654, 738)

QLPVNRW
TRRQVILCGTCLIVSSVKDSLSGKMHVLPLIGGKVEEVKKH-QHCLAFSSSGPQSQTYYI
CFDTFTEYLRWLRQVSKVASQRISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLRQNP
TLPAARGLGELQRF-TKLKSLNFSNNHLGAFPSAVCSI

PF13855 // ENSGT00440000037833_1_Domain_4 (819, 876)

PTLAELNVSCNALREVPAAVGA
MQNLQTFLLDGNFLQSLPAELENMHQLSYLGLSFNEFTDIPEVLEKLTAVDKLCMAGNCM
ETLRLQAFRRMPHIKHVDLRLNILRKLIA-DEVDFV

PF13516 // ENSGT00440000037833_1_Domain_8 (937, 952)

QHVTQLDLRDNKLGDLDAMIFNNI
EVLH----------------------C----------------ERNQLVTLNICGYF---
LKALYASSNELIQLDVYPVPNYLSYMDVSRNCLENVPEWVCESRKLEVLDIGHNQICELP
ARLFCNSSLRKLLAGHNQLARLPERLERTSVEVLDVQHNQLIELPPNLFMKADSLRFLNA
SANKLETLPPATLSEETSS---I

PF13855 // ENSGT00440000037833_1_Domain_15 (1164, 1279)

LQELYLTNNSL----------------------TDKC
VPLLTGHPRLKILHMAYNRLQSFPA-SKMAK-----------------------------
-----LEELEEIDVSGNKLKAIPTTIMNCRRMHTVIAHSNCIEVFPEVMQLPEVKCVDLS
CNELSEISLPENLPPKLQELDLTGNPRLALDHRSLELLN-NIRCFKIDQPSAG----DAS
GAPAVWSH

PF00481 // ENSGT00440000037833_1_Domain_18 (1389, 1632)

GYTEASGVKNKLCVAALSVNNFRDNREALYGVFDGDRNVEVPYLLQCTMSDI
LAEELQKTKNEDEYMVNTFIVMQRKLGTAGQKLGGAAVLCHIKHDPVDLGGSFTLTSANV
GKCQTVLCRNGKPLPLSRSYTMSCEEELIRIKQHKAIITED-GKVN--GVTES-TRILG-
YTFLHPNVVPRPHVQSVLLTPQDEFFILGSKGLWDSLSIEEAVEAVRNVPDALAAAKKLC
TLAQSYGCHDSISAVVVQLSVTEDSFCCCELSAGGSMPPPSPGIFPPSVNMVIKDRPSDG
LGVPSSSSGMASEISSELSTSEMSSEVGSTASDEPP-SGVLNE--NSPAYPSEQRCMLHP
VCLSNSFQRQLSS----ATFSSAFSDNGLDSDDEEPIEGVFSNGSRVE------VEVDIH
CSRAKEKERQQ-HLLQVPAEASDEGIVISANEDEAGLSKK-ADFSAVGTIGRRRANGSVA
PQERSHNVIEVATDAPLRKPGGYFAAPAQPDPDDQFIIPPELEEEVKEIMKHHQEQQQQQ
QQQQQ----QQVPPPPSQPQPQSQPQLQPQPQPQRQFQMDHLPDCYDTPL

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------DGASDP-------------RDCVFES----
----HTKPCLQFR---------VPEGPHFQLAGKIKLICKAGEQQVNEKRPSGRLQQQRA
QYSPVTGGEGGQNLTIAG-SCSS-------------LL---------------------V
SLACPQPPSAK-TSPSLQPKAPRGVDGTG-------GMASQGPKEDKAVAAAAPAGPLST
--PGRIRETAQK-------TTSPPSLYVQFHGETTRRLEADEKPLQIQNDYLFQLGFG--
ELWRVQE----EGMDSEIGCLIRFY--AGKPHSTGSSERIQLSGMYNVRKGKM

PF00169 // ENSGT00440000037833_1_Domain_0 (654, 738)

QLPVNRW
TRRQVILCGTCLIVSSVKDSLSGKMHVLPLIGGKVEEVKKH-QHCLAFSSSGPQSQTYYI
CFDTFTEYLRWLRQVSKVASQRISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLRQNP
TLPAARGLGELQRF-TKLKSLNFSNNHLGAFPSAVCSI

PF13855 // ENSGT00440000037833_1_Domain_4 (819, 876)

PTLAELNVSCNALREVPAAVGA
MQNLQTFLLDGNFLQSLPAELENMHQLSYLGLSFNEFTDIPEVLEKLTAVDKLCMAGNCM
ETLRLQAFRRMPHIKHVDLRLNILRKLIA-DEVDFV

PF13516 // ENSGT00440000037833_1_Domain_8 (937, 952)

QHVTQLDLRDNKLGDLDAMIFNNI
EVLH----------------------C----------------ERNQLVTLNICGYF---
LKALYASSNELIQLDVYPVPNYLSYMDVSRNCLENVPEWVCESRKLEVLDIGHNQICELP
ARLFCNSSLRKLLAGHNQLARLPERLERTSVEVLDVQHNQLIELPPNLFMKADSLRFLNA
SANKLETLPPATLSEETSS---I

PF13855 // ENSGT00440000037833_1_Domain_15 (1164, 1279)

LQELYLTNNSL----------------------TDKC
VPLLTGHPRLKILHMAYNRLQSFPA-SKMAK-----------------------------
-----LEELEEIDVSGNKLKAIPTTIMNCRRMHTVIAHSNCIEVFPEVMQLPEVKCVDLS
CNELSEISLPENLPPKLQELDLTGNPRLALDHRSLELLN-NIRCFKIDQPSAG----DAS
GAPAVWSH

PF00481 // ENSGT00440000037833_1_Domain_18 (1389, 1632)

GYTEASGVKNKLCVAALSVNNFRDNREALYGVFDGDRNVEVPYLLQCTMSDI
LAEELQKTKNEDEYMVNTFIVMQRKLGTAGQKLGGAAVLCHIKHDPVDLGGSFTLTSANV
GKCQTVLCRNGKPLPLSRSYTMSCEEELIRIKQHKAIITED-GKVN--GVTES-TRILG-
YTFLHPNVVPRPHVQSVLLTPQDEFFILGSKGLWDSLSIEEAVEAVRNVPDALAAAKKLC
TLAQSYGCHDSISAVVVQLSVTEDSFCCCELSAGGSMPPPSPGIFPPSVNMVIKDRPSDG
LGVPSSSSGMASEISSELSTSEMSSEVGSTASDEPP-SGVLNE--NSPAYPSEQRCMLHP
VCLSNSFQRQLSS----ATFSSAFSDNGLDSDDEEPIEGVFSNGSRVE------VEVDIH
CSRAKEKERQQ-HLLQVPAEASDEGIVISANEDEAGLSKK-ADFSAVGTIGRRRANGSVA
PQERSHNVIEVATDAPLRKPGGYFAAPAQPDPDDQFIIPPELEEEVKEIMKHHQEQQQQQ
QQQQ----QQQVPPPPSQPQPQSQPQLQPQPQPQRQFQMDHLPDCYDTPL

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------VAYPGCPYRLR-------------VPES
PHSELAGKICQPGHLASRSGG------VRGT-------------------------KSVP
GQGVQQQR------------AQCPPATASSCPGET-------------------FPGGPA
SPP--------GAPRRLDGAPA----G------------PASDTESFSLSPSAE--SVSD
RLDPYSSGGGG--------GGGGGGSSSSEELEADPSQ---------------PRRPGLP
VQ--PPPPSQTAAPPPPPQKAP------D-------GAAREGSPG-DTA-VAAPGSPLSP
TGRSGER--MA------EKAPPPPTLYVQLHGETTRRLEADEKPLQIQNDYLFQLGFG--
ELWRVQE----EGLDSEVGCLIRFY--AGKPHSTGSSERIQLSGMYNVRKGKM

PF00169 // ENSGT00440000037833_1_Domain_0 (654, 738)

QLPVNRW
TRRQVILCGTCLIVSSVKDSLTGKMHVLPLIGGKVEEVKKH-QHCLAFSSSGPQSQTYYI
CFDTFTEYLRWLRQVSKVASQRISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLRQNP
SLPAARGLGELQRF-TKLKSLNLSNNHLGNFPLAVCSI

PF13855 // ENSGT00440000037833_1_Domain_4 (819, 876)

PTLAELNVSCNALRAVPAAVGA
MHNLQTFLLDGNFLQSLPAELENMHQLSYLGLSFNEFTDIPEVLEKLTAVDKLCMSGNCM
ETLRLQSLRRMPHIKHVDLRLNIIKKLVS-DEVEFL

PF13516 // ENSGT00440000037833_1_Domain_8 (937, 952)

QHITQLDLRDNKLGDLDAMIFNNI
EVLH----------------------C----------------ERNQLVTLNICGYF---
LKALYASSNELVQLDVYPVPNYLSYLDVSRNHLENVPEWVCESRKLEVLDIGHNQICELP
ARLFCNSSLRKLLAGHNQLTRLPERLERTSVEVLDVQHNQLIELPPNLLMKADSLRFLNA
SANKLESLPPATLSEETSS---I

PF13855 // ENSGT00440000037833_1_Domain_15 (1164, 1279)

LQELYLTNNNL----------------------TDKC
VPLLTGHPHLKILHMAYNRLQSFPA-SKMAK-----------------------------
-----LEELEEVDISGNKLKAIPTTVINCRRMHTVIAHSNCLEVFPEVMQLPEIKCVDLS
CNELSEVTLPESLPPKLQELDLTGNPRLTLDHKTLELLN-NIRCFKIDQPSAA----DAS
GAPAVWSH

PF00481 // ENSGT00440000037833_1_Domain_18 (1389, 1632)

GYTEASGVKNKLCVAALSVNNFRDNREALYGVFDGDRNVEVPYLLQCTMSDI
LAEELQKTKNEEEYMVNTFIVMQRKLGTAGQKLGGAAVLCHIKHDPVDPGGSFTLTSANV
GKCQTVLCRNGKPLPLSRSYVMSCEEELKRIKQHKAIVTED-GKVN--GVTES-TRILG-
YTFLHPSVVPRPHVQSVLLTPQDEFFILGNKGLWDSLSIGEAVEAVRNVPDARAAAKKLC
TLAQSYGCHDSISAVVVQLSVTEDSFCCCELSASSSVPPPSPGIFSPSVNMVIKDRPSDG
LGVPSSSSGMASEISSELSTSEMSSEVGSTASDEPPSSGALNE--SSPAYPSEQRCMLHP
VSLSNSFQRQLSS----ATFSSAFSDNGLDSDDEEPIEGVFSNGSRVE------VEVDIH
CSRAKEKERQQ-HLLQVPAEASDEGIVISANEDESGLPRK-ADF--LGTIGRRRVNGSVA
PQERSHNVIEVATDAPLRKPGGYFAAPAQPDPDDQFIIPPELEEEVKEMMKHHQEQQQPS
PPPQP--Q---------------------QPPPQRQFHTDQLPDYYDTPL

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------MLQLQPSDRDWVRHQLQRGCVHVFDRHMASTYLRPVLCTLDT
TAGEVAARLLQLGHK----GGGVVKVLGQGPVPAVT--PARAEPPL--DAGSRLAPPEPR
DQEPPPARSA---PGAVGGPQNTPPA-DLPLPPGGP-------------GGWIRCPSRAS
PAPSDSSPGEL----------CGPRRLDGGTAGPA------SDTESFSLSPSAE--SVSD
RLDPYSSGGGAPAA-GER-GADP-------------APAPTVATGQ-P-R-------RPC
RPAHPRQPSPSASPPRPQQKAPRGVDVLG-------GAAREGS--QEEAAAA-PSGPPAT
--PRRSGVTAEK-------APSPPTLYVQLHGETTRRLEADEKPLQIQNDYLFQLGFG--
ELWRVQ-EE---GMDSEVGCLIRFY--AGKPHSTSSSERIQLSGMYNVRKGKM

PF00169 // ENSGT00440000037833_1_Domain_0 (654, 738)

QLPVNRW
TRRQVILCGTCLIVSSVKDSLTGKMHVLPLIGGKVEEVKKH-QHCLAFSSSGPQSQTYYI
CFDTFTEYLRWLRQVSKVASQRISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLRQSP
SLPTARGLSELQRF-

PF13516 // ENSGT00440000037833_1_Domain_3 (796, 810)

TKLKSLNLSNNHLG

ENSGT00440000037833_1_Linker_3_4 (810, 819)

DFPLAVCSI

PF13855 // ENSGT00440000037833_1_Domain_4 (819, 876)

PTLAELNVSCNALRAVPAAVGA
MHNLQTFLLDGNFLQSLPAELENMHQLSYLGLSFNEFTDIPEVLEKLTAVDKLCMSGNCM
ETLRLQALRRMPHIKHVDLRLNIIRKLVA-DEVDFL

PF13516 // ENSGT00440000037833_1_Domain_8 (937, 952)

QHITQLDLRDNKLGDLDAMIFNNI
EVLH----------------------C----------------ERNQLVTLNICGYF---
LKSLYASYNELVQLDVYPVPNHLSYMDVSRNHLENVPEWVCESRKLEVLDIGHNQICELP
ARLFYNSSLRKLLAGHNRLARLPERLERTSVEVLDVQHNQLIELPPNLLMKADSLRFLNA
SANKLETLPPATLSEETNS---I

PF13855 // ENSGT00440000037833_1_Domain_15 (1164, 1279)

LQELYLTNNNL----------------------TDKC
VPLLTGHPRLKILHMAYNRLQSFPA-SKMAK-----------------------------
-----LEELEEIDISGNKLKAIPTTIMNCRRMHTVIAHSNCIEVFPEVMQLPEIKCVDLS
CNELSEVTLPENLPPKLQELDLTGNPRLALDHKTLELLN-NIRCFKIDQPSAG----DAS
GAPAVWSH

PF00481 // ENSGT00440000037833_1_Domain_18 (1389, 1632)

GYTEASGVKNKLCVAALSVNNFCDNREALYGVFDGDRNVEVPYLLQCTMSDI
LAEELQKTKNEEEYMVNTFIVMQRKLGTAGQKLGGAAVLCHIKHDPVDPGGSFTLTSANV
GKCQTVLCRNGKPLPLSRSYVMSCEEELKRIKQHKAIITED-GKVN--GVTES-TRILG-
YTFLHPSVVPRPHVQSVLLTPQDEFFILGSKGLWDSLSIEEAVEAVRNVPDALAAAKKLC
TLAQSYGCHDSISAVVVQLSVTEDSFCCCELSGGGSVPPPSPGIFPPSVNMVIKDRPSDG
LGVPSSSSGMASEISSELSTSEMSSEVGSTASDEPP-SGALNE--SSPAYPSEQRCMLHP
VCLSNSFQRQLSS----ATFSSAFSDNGLDSDDEEPIEGVFTNGSRVE------VEVDIH
CTRAKEKEKQQ-HLLQVPAEASDEGIVISANEDEPGLPRK-ADFSAVGTIGRRRANGSVA
PQERSHNVIEVATDAPLRKPGGYFAAPAQPDPDDQFIIPPELEEEVKEIMKHHQEQQ---
------------------------------QPPQRQFQMDQLPDCYDTPL

MEPAAAATAQRLPEPGREERASAPAAAAAAAAAAAAAATAAAALAAAAGGGRSPEPALTP
AAPSGGNGSGGGAREEAPGEAPPGPLPGRAG-GAGRRRRRGA-PQPIAGGAAPVPGAGS-
--GANSLLLRRGRLKRNLAAAAAAASSSS----SSSSSAAAASHSPGAAGLPASCSASAS
LCTRSLDRKTLLLKH-RQTLQLQPSDRDWVRHQLQRGCVHVFDRHMASTYLRPVLCTLDT
TAGEVAARLLQLGHK----GGGVVKVLGQGPGAAAAREPAEP----PPEAGPRLAPPEPR
DSEALPARSA---PGAVGGPPRAPPA-DLPLPAGVP-------------GGWSR---RAS
PAPSDSSPGEPFV-----GGPASSPRAPRPVA---------SDTESFSLSPSAE--SVSD
RLDPYSSGGG-SS-SSEEVETDA-------------ASAPTAVPGQ-PR--------RPG
RSAQPLPPPQTASSPRPQQKAPRAVDSPG-------GAVREGPCEEKAAAFVAPGGLQST
--PGRSGVTAEKAAPPP----PPPTLYVQLHGETTRRLEAEEKPLQIQNDYLFQLGFG--
ELWRVQE----EGMDSEIGCLIRFY--AGKPHSTGSSERIQLSGMYNVRKGKM

PF00169 // ENSGT00440000037833_1_Domain_0 (654, 738)

QLPVNRW
TRRQVILCGTCLIVSSVKDSLTGKMHVLPLIGGKVEEVKKH-QHCLAFSSSGPQSQTYYI
CFDTFTEYLRWLRQVSKVASQRISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLRQNP
SLPAARGLNELQRF-

PF13516 // ENSGT00440000037833_1_Domain_3 (796, 810)

TKLKSLNLSNNHLG

ENSGT00440000037833_1_Linker_3_4 (810, 819)

DFPLAVCSI

PF13855 // ENSGT00440000037833_1_Domain_4 (819, 876)

PTLAELNVSCNALRSVPAAVGV
MHNLQTFLLDGNFLQTLPAELENMKQLSYLGLSFNEFTDIPEVLEKLTAVDKLCMSGNCM
ETLRLQALRKMPHIKHVDLRLNIIRKLIA-DEVDFL

PF13516 // ENSGT00440000037833_1_Domain_8 (937, 952)

QHVTQLDLRDNKLGDLDAMIFNNI
EVLH----------------------C----------------ERNQLVTLDICGYF---
LKALYASSNELVQLDVYPVPNYLSYMDVSRNRLENVPEWVCESRKLEVLDIGHNQICELP
ARLFCNSSLRKLLAGHNQLARLPERLERTSVEVLDVQHNQLLELPPNLLMKADSLRFLNA
SANKLESLPPATLSEETNS---I

PF13855 // ENSGT00440000037833_1_Domain_15 (1164, 1279)

LQELYLTNNSL----------------------TDKC
VPLLTGHPHLKILHMAYNRLQSFPA-SKMAK-----------------------------
-----LEELEEIDLSGNKLKAIPTTIMNCRRVHTVIAHSNCIEVFPEVMQLPEIKCVDLS
CNELSEVTLPENLPPKLQELDLTGNPRLVLDHKTLELLN-NIRCFKIDQPSTG----DAS
GAPAVWSH

PF00481 // ENSGT00440000037833_1_Domain_18 (1389, 1632)

GYTEASGVKNKLCVAALSVNNFCDNREALYGVFDGDRNVEVPYLLQCTMSDI
LAEELQKTKNEEEYMVNTFIVMQRKLGTAGQKLGGAAVLCHIKHDPVDPGGSFTLTSANV
GKCQTVLCRNGKPLPLSRSYIMSCEEELKRIKQHKAIITED-GKVN--GVTES-TRILG-
YTFLHPSVVPRPHVQSVLLTPQDEFFILGSKGLWDSLSLEEAVEAVRNVPDAQAAAKKLC
TLAQSYGCHDSISAVVVQLSVTEDSFCCCELSAGGAVPPPSPGIFPPSVNMVIKDRPSDG
LGVPSSSSGMASEISSELSTSEMSSEVGSTASDEPP-PGALSE--NSPAYPSEQRCMLHP
VCLSNSFQRQLSS----ATFSSAFSDNGLDSDDEEPIEGVFTNGSRVE------VEVDIH
CSRAKEKEKQQ-HLLQVPAEASDEGIVISANEDEPGLPRK-ADFSAVGTIGRRRANGSVA
PQERSHNMIEVATDAPLRKPGGYFAAPAQPDPDDQFIIPPELEEEVKEIMKHHQEQQ---
QQQQ-PP---PP---P---------QL--QPQLPRHYQLDQLPDYYDTPL

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------LFC-NIYF--VGKSNCGGFSERTQLSGTYNVRKGKMQLPVNRW
ARRQVILCGTCLIVSSVKESQTGKMHILPLIGGKVEEVKKH-QHCLAFSSSGPQSQTYYI
CFDTFTDYLRWLRQASKIASQRTSSVDLSCCSLEYLPENLFYSQDITHLNLKQNILRLSP
GPAAEGTLDDLQRF-T

PF00560 // ENSGT00440000037833_1_Domain_3 (797, 818)

KLRSLNLSNNNLGSFPLAVCS

ENSGT00440000037833_1_Linker_3_5 (818, 820)

IP

PF00560 // ENSGT00440000037833_1_Domain_5 (820, 841)

TLTELNLSCNALRAIPSQVGD

ENSGT00440000037833_1_Linker_5_4 (841, 843)

MN

PF00560 // ENSGT00440000037833_1_Domain_4 (843, 864)

NLQTFLLDGNYLQSLPAEMGN

ENSGT00440000037833_1_Linker_4_6 (864, 866)

MH

PF00560 // ENSGT00440000037833_1_Domain_6 (866, 887)

QLNYLGLSFNEFTDIPEVVEKMASMDRLCMPGNAL
DILELQTLRKMSQIKHVDLRLNEIRGLVI-DEPDFLP

PF00560 // ENSGT00440000037833_1_Domain_8 (938, 960)

HITQLDLRDNKLTDLDVTALSN

ENSGT00440000037833_1_Linker_8_9 (960, 1042)

L
EVLH----------------------C----------------ERNRLRCLKISGFF---
LKALYASSNELLNLDVYPNPC

PF00560 // ENSGT00440000037833_1_Domain_9 (1042, 1063)

YLSYMDISRNCLHSLPEWFSE

ENSGT00440000037833_1_Linker_9_10 (1063, 1065)

CR

PF00560 // ENSGT00440000037833_1_Domain_10 (1065, 1087)

NLEVLDVSHNHLNELP
DRLFCT

ENSGT00440000037833_1_Linker_10_11 (1087, 1088)

S

PF00560 // ENSGT00440000037833_1_Domain_11 (1088, 1109)

ALRKLLLGYNQLQRLPELIEN

ENSGT00440000037833_1_Linker_11_12 (1109, 1110)

N

PF00560 // ENSGT00440000037833_1_Domain_12 (1110, 1132)

QLEVLDVQHNQLLELPANLLLKLNSLRCLNA
SANHLETLPATCLSEESHS---

PF00560 // ENSGT00440000037833_1_Domain_14 (1163, 1207)

MLQELYLTNNNL----------------------TDKC
VPLLMG

ENSGT00440000037833_1_Linker_14_15 (1207, 1209)

HP

PF00560 // ENSGT00440000037833_1_Domain_15 (1209, 1266)

HLKILHMAFNHLQTFPA-SKMAK-----------------------------
-----

ENSGT00440000037833_1_Linker_15_16 (1266, 1268)

LE

PF00560 // ENSGT00440000037833_1_Domain_16 (1268, 1289)

ELEEIDISGNKLKAMPTTIMNCRRMHTVIAHSNCLEVFPEVMQLSEIKCVDLS
CNELTEITLPENLPPRLQELDLTGNARLLLDHKTLELLNSNIRFFKVDQPSCGFSGSEAS
GVPAV

PF00481 // ENSGT00440000037833_1_Domain_18 (1386, 1632)

WSHGYAEASGVKSKLCVASLLVNNFCDNREAVYGVFDGERNVEVPSLLQCTMSDI
LADELQKTKSEEEYMGNTFLVMQRKLGTAGQKLGGSAVLCHIKHDPMDPAGCFTLTTANV
GKCQTVICRDGKPLNLSKHLTVSCEEELKRIKQHKAIITED-GKVN--GVTDS-TRILG-
YTFLHPSVTPRPHVQSVTLTPQDEFFILGSKGLWDSLSMEEAVETVRNVPDALAASKKLC
SLAQSYGCSGSLCAVVVQLNVTEDCICCCELN--GGMPPPSPGIFTPSVNVVIKDRAPDS
LGMPSSSSGLASEISSEISTSEMSSEVGSTASDEPPAVSLHENGVGPVGCPTEQRCTLHP
VCLSSSFQRQLSS----ATFSSAFSDNGLDSEDEEPIEGVFSNGSRVE------VEVDIH
CSRTKSGCQT---VPAVLTESTDEGIVINGNEDDMGGPGKRQDFSSNTLGRQRRGNGSVA
PLEKSHNLIEIAADAPLRKQGGYFAAPAQPDPDDQFIIPPELEEEVKEIM----------
--------------------------------------------------

MEPAAAAPAQRLADPTGEDQALAA---------------------AAAEGGRCPDPALSA
AAPSGGN--GGAAREEAPCEAPPGPLPGRAG-GTGRRRRRGA-PQPAAGGAAPVPAAGG-
--GANSLLLKRGRLKRNLSAAAAASSSSSP-----------SSASSAAGGLPASCSASAS
LCTRSLDRKTLLLKH-RQLLQLQPSDRDWVRHQLQRGCVHVFDRHMASSYLRPVLCTLDT
TAAEVAARLLQLGHK----GGGVVKVLGYGPPPAAAPAASDQ----TLDGEHG------R
DVEPPPSSGT---VGAVRGPARAPPA-DLPLPGG----------------AWTRCAPRIS
PAPSDSSPGELFA-----GGPGSPPRAPRPA----------SDTESFSLSPSAE--SVSD
RLDPYSSGGGGSSSSSEELEADPA-----------M-------------------PHRPG
RPAQP-RPPSPKTSALLQPKAPTGVDSTG-------VIAGEGPGDDKAMAAAAPDVPLST
--SGRIRETVQ-------KT-SPPSLYVQLHGETTRRLEADEKPLQIQNDYLFQLGFG--
ELWRVQE----EGMDSEIGCLIRFY--AGKPHSTGSSERIQLSGMYNVRKGKM

PF00169 // ENSGT00440000037833_1_Domain_0 (654, 738)

QLPVNRW
TRRQVILCGTCLIVSSVKDSVSGKMHVLPLIGGKVEEVKKH-QHCLAFSSSGPQSQTYYI
CFDTFTEYLRWLRQVSKVASQRISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLRQTP
TLPAARGLGELQRF-TKLKSLNLSNNHLGAFPSAVCSIPTLAELNVSCNALREVPAAVGD
MQNLQTFLLDGNFLQSLPAELESMHQLSYLGLSFNEFTDIPEVLEKLTAVDKLCMAGNCV
ETLRLQALRRMPHIKHVDLRLNILRKLMA-DEVDFV

PF13516 // ENSGT00440000037833_1_Domain_8 (937, 952)

QHVTQLDLRDNKLGDLDAMIFNNI
EVLH----------------------C----------------ERNQLVTLNVCGYF---
LKALYASSNELAQLDVYPVPNYLSYMDVSRNCLESVPEWVCESRKLEVLDIGHNQICELP
ARLFCNSSLRKLLAGHNRLARLPERLERTSVEVLDVQHNQITELPPNLLMKADSLRFLNA
SANKLETLPPATLSEETSS---I

PF13855 // ENSGT00440000037833_1_Domain_15 (1164, 1279)

LQELYLTNNCL----------------------TDKC
VPLLTGHPRLKILHMAYNRLQSFPA-SKMAK-----------------------------
-----LEELEEIDISGNKLKAIPTTIMNCRRMHTVIAHSNCIEVFPEVMQLPEVKCVDLS
CNELSEITLPENLPPKLQELDLTGNPRLALDHKSLELLN-NIRCFKIDQPSAG----DAS
GAPAVWSH

PF00481 // ENSGT00440000037833_1_Domain_18 (1389, 1632)

GYTEASGVKNKLCVAALSVNNFRDNREALYGVFDGDRNVEVPYLLQCTMSDI
LAEELQKTKNEEEYMVNTFIVMQRKLGTAGQKLGGAAVLCHIKPDPVDLGGSFTLTSANV
GKCQTVLCRNGKPLSLSRSYIMSCEEERKRIKQHKAIITED-GKVN--GVTES-TRILG-
YTFLHPSVVPRPHVQSVLLTPQDEFFILGSKGLWDSLSIDEAVEAVRNVPDALAAAKKLC
TLAQSYGCHDSISAVVVQLSVTEDSFCCCELSAGGSMPPPSPGIFPPSVNMVIKDRPSDG
LGVPSSSSGMASEISSELSTSEMSSEVGSTASDEPP-SGVLNE--SSPAYPNEQRCMLHP
VCLSNSFQRQLSS----ATFSSAFSDNGLDSDDEEPIEGVFSNGSRVE------VEVDIH
CSRAKEKERQQ-HLLQVPAEASDEGIVISANEDESGLSKK-ADFSAVGTIGRRRANGSVA
PQERSHNVIEVAADAPLRKPGGYFAAPAQPDPDDQFIIPPELEEEVKEIMKHHQEQQQQQ
QQQ--QL---PPPPQPPQ--PQPQPQPQPQPQPQRHFQMDHLPDCYDTPL

MEPAAAATAQRLPEPGREDRASAPAAAAAAAA---AAAAAAAALAAAAGGGRSPEPALTP
GTPSGGNG-GGGAREEAPGEAPLGPLPGRAG-GTGRRRRRGA-PLPNAGGAAPVPGAGG-
--GTNSLLLRRGRLKRNLSAAAAAAS-------SSSSLAAAASHSPGAAGLPASCSASAS
LCTRSLDRKTLLLKH-RQTLQLQPSDRDWVRHQLQRGCVHVFDRHMASTYQRPVLCTLDT
TAGEVAARLLQLGHK----GGGVVKVLGQGPGAAAAREAAEP----PLEAGPRLAPPEPP
DSEAPPARSA---PGAVGGPPSAPPA-DLPLPSGGP-------------GGWTL---RAS
PAPSDLSPGEPFA-----GGPASPPHARRPVA---------SDTESFSLSPSAE--SVSD
RLDPYSSGGGSSSS-SEELEAD-------------PASAPMGVPGP-PR--------RPG
RPAQPRPPSQTATLPPLQQKAPRAVDSPG-------GAAREGLCREKTATVAAPGGPQ--
STPRRSGAIAEK---VP----PPPTLYVQLHGETTRRLEAEEKPLQIQNDYLFQLGFG--
ELWRVQE----EGMDSEIGCLIRFY--AGKPHSTGSSERIQLSGMYNVRKGKM

PF00169 // ENSGT00440000037833_1_Domain_0 (654, 738)

QLPVNRW
TRRQVILCGTCLIVSSVKDSLTGKMHVLPLIGGKVEEVKKH-QHCLAFSSSGPQSQTYYI
CFDTFTEYLRWLRQVSKVASQRISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLRQNP
SLPAARGLNELQRF-

PF13516 // ENSGT00440000037833_1_Domain_3 (796, 810)

TKLKSLNLSNNHLG

ENSGT00440000037833_1_Linker_3_4 (810, 819)

DFPLAVCNI

PF13855 // ENSGT00440000037833_1_Domain_4 (819, 876)

PTLAELNVSCNALRSVPADVGV
MHNLQTFLLDGNFLQSLPAELENMKQLSYLGLSFNEFTDIPEVLEKLTAVDKLCMSGNCM
ETLRLQALRKMPHIKHVDLRLNVIRKLIA-DEVDFL

PF13516 // ENSGT00440000037833_1_Domain_8 (937, 952)

QHVTQLDLRDNKLGDLDAMIFNNI
EVLH----------------------C----------------ERNQLVTLDICGYF---
LKALYASSNELVQVDVYPVPNYLSYMDVSRNRLENVPEWVCESRKLEVLDIGHNQICELP
ARLFCNSSLRKLLAGHNQLARLPERLERTSVEVLDVQHNQLQELPPNLLMKADSLRFLNA
SANKLESLPPATLSEETNS---I

PF13855 // ENSGT00440000037833_1_Domain_15 (1164, 1279)

LQELYLTNNSL----------------------TDKC
VPLLTGHPHLKILHMAYNRLQSFPA-SKMAK-----------------------------
-----LEELEEIDLSGNKLKAIPTTIMNCRRMHTVIAHSNCIEVFPEVMQLPEIKCVDLS
CNELSEVTLPENLPPKLQELDLTGNPRLVLDHKTLELLN-NIRCFKIDQPSTG----DAS
GAPAVWSH

PF00481 // ENSGT00440000037833_1_Domain_18 (1389, 1632)

GYTEASGVKNKLCVAALSVNNFCDNREALYGVFDGDRNVEVPYLLQCTMSDI
LAEELQKTKNEEEYMVNTFIVMQRKLGTAGQKLGGAAVLCHIKHDPVDPGGSFTLTSANV
GKCQTVLCRNGKPLPLSRSYIMSCEEELKRIKQHKAIITED-GKVN--GVTES-TRILG-
YTFLHPSVVPRPHVQSVLLTPQDEFFILGSKGLWDSLSVEEAVEAVRNVPDALAAAKKLC
TLAQSYGCHDSISAVVVQLSVTEDSFCCCELSAGGAVPPPSPGIFPSSVNMVIKDRPSDG
LGVPSSSSGMASEISSELSTSEMSSEVGSTASDEPP-PGALSE--NSPAYPSEQRCMLHP
VCLSNSFQRQLSS----ATFSSAFSDNGLDSDDEEPIEGVFTNGSRVE------VEVDIH
CSRAKEKEK-Q-HLLQVPAEASDEGIVISANEDEPGLPKK-ADFSAVGTIGRRRANGSVA
PQERSHNVIEVAADAPLRKPGGYFAAPAQPDPDDQFIIPPELEEEVKEIMKHHQEQQ---
--QQPPP---PP---P---------PL--QPQLPRHYQLDQLPDYYDTPL

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------------------------------------------------------------
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--------------EAAEKATPPPTLYVQLHGETTRRLEADEKPLQIQNDYLFQLGFG--
ELWRVQE----EGMDSEIGCLIRFY--AGKPHSTGSLER

PF00169 // ENSGT00440000037833_1_Domain_0 (640, 740)

IQLSGMYNVRKGKMQLPVNRW
TRRQVILCGTCLIVSSVKDSMTGKMHVLPLIGGKVEEVKKH-QHCLAFSSSGPQSQTYYI
CFDTFTEYLRWLRQVSKVA

ENSGT00440000037833_1_Linker_0_1 (740, 742)

SQ

PF00560 // ENSGT00440000037833_1_Domain_1 (742, 760)

RISSVDLSCCSLEHLPAN

ENSGT00440000037833_1_Linker_1_2 (760, 765)

LFYSQ

PF00560 // ENSGT00440000037833_1_Domain_2 (765, 785)

DLTHLNLKQNFLRQIP
SLPA

ENSGT00440000037833_1_Linker_2_3 (785, 797)

ARGLNELQRF-T

PF00560 // ENSGT00440000037833_1_Domain_3 (797, 818)

KLKSLNLSNNHLGDFPLAVCN

ENSGT00440000037833_1_Linker_3_5 (818, 820)

IP

PF00560 // ENSGT00440000037833_1_Domain_5 (820, 841)

TLTELNVSCNALRAVPAAVGV

ENSGT00440000037833_1_Linker_5_4 (841, 843)

MH

PF00560 // ENSGT00440000037833_1_Domain_4 (843, 864)

NLQTFLLDGNFLQSLPAELES

ENSGT00440000037833_1_Linker_4_6 (864, 866)

MH

PF00560 // ENSGT00440000037833_1_Domain_6 (866, 887)

QLSYLGLSFNEFTDIPEVLEKLTAVDKLCMSGNCM
ETLRLQALRKMPHIKHVDLRLNVIRKLIA-DEVDFLQHVTQLDLRDNKLGDLDAMIFNNI
EVLH----------------------C----------------ERNQLVTLRICGYF---
LKALYASSNELVQLDVYPIPNYLSYMDISRNRLESVPEWVCESR

PF00560 // ENSGT00440000037833_1_Domain_10 (1065, 1087)

KLEVLDIGHNQICELP
ARLFCN

ENSGT00440000037833_1_Linker_10_11 (1087, 1088)

S

PF00560 // ENSGT00440000037833_1_Domain_11 (1088, 1106)

SLRKLLAGHNQLTRLPERLERTLVEVLDVQHNQLLELPPSLLMKAD

PF00560 // ENSGT00440000037833_1_Domain_13 (1134, 1156)

SLRFLNA
SANKLETLPPATLSEETSS---ILQELYLTNNNL----------------------TDKC
VPLLTGHP

PF00560 // ENSGT00440000037833_1_Domain_15 (1209, 1266)

HLKILHMAYNRLQSFPA-SKMAK-----------------------------
-----

ENSGT00440000037833_1_Linker_15_16 (1266, 1268)

LE

PF00560 // ENSGT00440000037833_1_Domain_16 (1268, 1289)

ELEEVDISGNKLKAIPTTIMN

ENSGT00440000037833_1_Linker_16_17 (1289, 1336)

CRRMHTVIAHSNCIEVFPEVMQLPEMKCVDLS
CNELSEVTLPENLPP

PF00560 // ENSGT00440000037833_1_Domain_17 (1336, 1358)

KLQELDLTGNPRLTLDHKTLEL

ENSGT00440000037833_1_Linker_17_18 (1358, 1386)

LN-NIRCFKIDQPSAG----DAS
GAPAV

PF00481 // ENSGT00440000037833_1_Domain_18 (1386, 1632)

WSHGYTEASGVKNKLCVAALSVNNFCDNREALYGVFDGDRNVEVPYLLQCTMSDI
LAEELQKTKHEEEYMVNTFIVMQRKLGTAGQKLGGAAVLCHIKHDPVDPGGSFTLTSANV
GKCQTVLCRNGKPLPLSRSYSMSCEEELKRIKQHKAIITED-GKVN--GVTES-TRILG-
YTFLHPSVVPRPHVQSVTLTPQDEFFILGSKGLWDSLSIEEAVEAVRNVPDALAAAKKLC
TLAQSYGCHDSISAVVVQLNVTEDSFCCCELSASGAVPPPSPGIFPSSVNMVIKDRPSDG
LGMPSSSSGMASEISSEISTSEMSSEVGSTASDEPP-SGALNE--SSPAYPSE-------
------------------------------------------------------------
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--------------------------------------------------

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-----------------LSCLFVLV--VGKPHSTGSSERIQLSGTYNVRKGKMHLPVNRW
TRRQVILCGTCLIVSSVKDSVAGKMHVLPLIGGKVEEVKKH-QHCLAFSSSGPQSQTYYI
CFDTFTEYLRWFDKSPRVASQRISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLRQNP
SLPTARGLSELQRF-T

PF00560 // ENSGT00440000037833_1_Domain_3 (797, 814)

KLKSLNLSNNHLGDFPLAVCNIPTLAELNMSCNALRAVPAAVGA
MHNLQTFLLDGNFLQTLPAELENMHQLSYLGLSFNEFTDLPEVLQKLTAVEKLCMSGNCV
GTLRLQALRKMPHIKHVDLRLNVIRNLIA-DGVDFLPHVTQLDLRDNKLEGLDAVVFTNL
EVLH----------------------C----------------ERNQLVTLNACGCF---
LKALYASSNELVQLDVCPVPNYLSYMDVSRNCLENVPEWVCESR

PF00560 // ENSGT00440000037833_1_Domain_10 (1065, 1086)

KLEVLDIGHNQICELP
ARLFCNSSLRKLLAGHNRMARLPESLERTSVEVLDVQHNQLLELPPSLLMKADSLRFLNA
SANKLETLPPATLSEETNS---ILQELYLTNNNL----------------------TDKC
VSLLTGHPHLKVLHMAYNRLQSFPA-SKMAK-----------------------------
-----LEELEEIDLSGNKLKAVPTTIMNCRRMHTVTAHSNCIEVFPEVMQLPEIKCVDLS
CNELSEVTLPENLPPKLQELDLTGNPRLALDHRTLELLN-NIRCFKIDQPSAG----DAS
GAPAVWSH

PF00481 // ENSGT00440000037833_1_Domain_18 (1389, 1631)

GYTEASGVKNKLCVAALSVNNFCDNQEALYGVFDGDRNVEVPYLLQCTMSDI
LAEELQKTRDGEECMVNTFIVMQRKLGTAGQKLGGAAVLCHIRHDPVDPGGPFTLTSANV
GKCQTVLCRNGKPLPLSRSYVMSCEEELRRIKRHKAIVTED-GKVN--GVTES-TRILG-
YTFLHPSVVPRPHVQSVALSPQDEFFILGSKGLWDSLSVEEAVDAVRSVPDALAAAKKLC
TLAQSYGCRESVSAVVVQLSVPEDSFCCCELA---ALPPPSPGVFAPAAGVAVRERPADG
LGAPSSSSGLASEMSSELSTSEMSSEVGSTASDEPPPPGPLGE--GSPAGPGEPRCALHP
GGAPSAFQRQLSS----ATFSSAFSDNGLDSDDEEPIEGVFSNGSRVE------VAADIH
CGRARDGERRRP------PEAADEGVG--AVEDEPGASRR-VD-GAAGTMGRRRGNGSVA
PQERSHNVIEVAADAPLRRPGGYFAAPAQPDPDDQLIIPPELEEEVKEMMKQRPPAPPR-
-------------PGPAEPA--D--------------------CSCDTPL

------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
-----SSA----------ATASH-------------SPSAAGLPAS-CSASASLCTRSLD
RKTLLLKHRQ------TLQLQPSDRDWVR-------HQLQR-GCVHVFDRHMASTYLRPV
--LCTLDTTAGEV---A----ACLLQLGQLHGETTRRLEAEEKPLQIQNDYLFQLGFG--
ELWRVQE----EGMDSEIGCLIRFY--AGKPHSTGSSERIQLSGMYNVRKGKM

PF00169 // ENSGT00440000037833_1_Domain_0 (654, 738)

QLPVNRW
TRRQVILCGTCLIVSSVKDSLTGKMHVLPLIGGKVEEVKKH-QHCLAFSSSGPQSQTYYI
CFDTFTEYLRWLRQVSKVASQRISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLRQNP
SLPAARGLNELQRF-

PF13516 // ENSGT00440000037833_1_Domain_3 (796, 810)

TKLKSLNLSNNHLG

ENSGT00440000037833_1_Linker_3_4 (810, 819)

DFPLAVCSI

PF13855 // ENSGT00440000037833_1_Domain_4 (819, 876)

PTLAELNVSCNALRSVPAAVGV
MHNLQTFLLDGNFLQSLPAELENMKQLSYLGLSFNEFTDIPEVLEKLTAVDKLCMSGNCM
ETLRLQALRKMPHIKHVDLRLNIIRKLIA-DEVDFL

PF13516 // ENSGT00440000037833_1_Domain_8 (937, 952)

QHVTQLDLRDNKLGDLDAMIFNNI
EVLH----------------------C----------------ERNQLVTLDICGYF---
LKALYASSNELVQLDVYPVPNYLSYMDVSRNRLENVPEWVCESR

PF00560 // ENSGT00440000037833_1_Domain_10 (1065, 1086)

KLEVLDIGHNQICELP
ARLFCNSSLRKLLAGHNQLARLPERLERTSVEVLDVQHNQLLELPPNLLMKADSLRFLNA
SANKLESLPPATLSEETNS---I

PF13855 // ENSGT00440000037833_1_Domain_15 (1164, 1279)

LQELYLTNNSL----------------------TDKC
VPLLTGHPHLKILHMAYNRLQSFPA-SKMAK-----------------------------
-----LEELEEIDLSGNKLKAIPTTIMNCRRVHTVIAHSNCIEVFPEVMQLPEIKCVDLS
CNELSEVTLPENLPPKLQELDLTGNPRLVLDHKTLELLN-NIRCFKIDQPSTG----DAS
GAPAVWSH

PF00481 // ENSGT00440000037833_1_Domain_18 (1389, 1632)

GYTEASGVKNKLCVAALSVNNFCDNREALYGVFDGDRNVEVPYLLQCTMSDI
LAEELQKTKNEEEYMVNTFIVMQRKLGTAGQKLGGAAVLCHIKHDPVDPGGSFTLTSANV
GKCQTVLCRNGKPLPLSRSYIMSCEEELKRIKQHKAIITED-GKVN--GVTES-TRILG-
YTFLHPSVMPRPHVQSVLLTPQDEFFILGSKGLWDSLSVEEAVEAVRNVPDALAAAKKLC
TLAQSYGCHDSISAVVVQLSVTEDSFCCCELSASGAVPPPSPGIFPPSVNMVIKDRPSDG
LGVPSSSSGMASEISSELSTSEMSSEVGSTASDEPP-PGALSE--NSPAYPSEQRCMLHP
VCLSNSFQRQLSS----ATFSSAFSDNGLDSDDEEPIEGVFTNGSRVE------VEVDIH
CSRAKEKEKQQ-HLLQVPAEASDEGIVISANEDEPGLPRK-ADFSAVGTIGRRRANGSVA
PQERSHNVIEVATDAPLRKPGGYFAAPAQPDPDDQFIIPPELEEEVKEIMKHHQEQQ---
QQQQ-PP---PP---P---------QL--QPQLPRHYQLDQLPDYYDTPL

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------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
-----------------------------KPHSTGSSER

PF00169 // ENSGT00440000037833_1_Domain_0 (640, 740)

IQLSGMYNVRKGKMQLPVNRW
TRRQVILCGTCLIVSSVKDSFTGKMHVLPLIGGKVEEVKKH-QHCLAFSSSGPQSQTYYI
CFDTFTEYLRWLRQVSKVA

ENSGT00440000037833_1_Linker_0_1 (740, 742)

SQ

PF00560 // ENSGT00440000037833_1_Domain_1 (742, 760)

RISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLRQSP
SLPTARGLNELQRF-S

PF00560 // ENSGT00440000037833_1_Domain_3 (797, 818)

KLKCLNLSNNHLGDFPLAVCNIPTLAELNVSCNALRAVPAAVGD
MH

PF00560 // ENSGT00440000037833_1_Domain_4 (843, 864)

NLQTFLLDGNFLQTLPAELEN

ENSGT00440000037833_1_Linker_4_6 (864, 866)

MH

PF00560 // ENSGT00440000037833_1_Domain_6 (866, 887)

QLSYLGLSFNEFTDIPEVLEKLTAVEKLCMSGNCM
ETLRLQALRKMPHIKHVDLRLNLIRKLIA-DEVDFLPHVTQLDLRDNKLRDLDAMVFNNI
EVLH----------------------C----------------ERNQLVTLNICGYF---
LKALYTSSNELVQLDVYPVPNYLSYMDVSRNRLENVPEWVCESR

PF00560 // ENSGT00440000037833_1_Domain_10 (1065, 1087)

KLEVLDIGHNQICELP
ARLFCN

ENSGT00440000037833_1_Linker_10_11 (1087, 1088)

S

PF00560 // ENSGT00440000037833_1_Domain_11 (1088, 1106)

SLRKLLAGHNQLTRLPER

ENSGT00440000037833_1_Linker_11_12 (1106, 1110)

LERT

PF00560 // ENSGT00440000037833_1_Domain_12 (1110, 1128)

SVEVLDVQHNQLLELPPN

ENSGT00440000037833_1_Linker_12_13 (1128, 1134)

LLMKAD

PF00560 // ENSGT00440000037833_1_Domain_13 (1134, 1156)

SLRFLNA
SANQLVNLPPATLSEETNS---VLQELYLTINNL----------------------TYKC
VPLLTGHPHLKILHIVYIRLLSFPA-SKMAK-----------------------------
-----LE

PF00560 // ENSGT00440000037833_1_Domain_16 (1268, 1289)

ELEEIDISGNKLKAVPTTIMN

ENSGT00440000037833_1_Linker_16_17 (1289, 1336)

CRRMHTVIAHSNCIEVFPEVMQLPEIKCVDLS
CNELSEVTLPENLPP

PF00560 // ENSGT00440000037833_1_Domain_17 (1336, 1358)

KLQELDLTGNPRLALDHKTLEL

ENSGT00440000037833_1_Linker_17_18 (1358, 1386)

LN-NIRCFKIDQPSGG----DAS
GAPAV

PF00481 // ENSGT00440000037833_1_Domain_18 (1386, 1632)

WSHGYTEASGVKNKLCVAALSVNNFRDNREALYGVFDGDRNVEVPYLLQCTMSDI
LAEELQKTKNEEEYMVNTFIVMQRKLGTAGQKLGGAAVLCHIKHDPVDPGGPFTLTSANV
GKCQTVLCRNGKPLPLSRSYVMSCEEELKRIKRHKAIITED-GKVN--GVTES-TRILG-
YTFLHPSVVPRPHVQSVALTPQDEFFILGSKGLWDSLSVEEAVGAVRNVPDALAAAKKLC
TLAQSYGCRDSVSAVVVQLSVPEDSFCCCELGAGGPVPPPSPGTFPPSVSMVIKERPADG
LGVPSSSSGLASEMSSELSTSEMSSEVGSTASDEPP-PGALSE--SSPACPSEPRCSLHP
ACPSSSFQRQLSS----ATFSSAFSDNGLDSDDEEPIEGVFTNGSRVE------VEVDIH
CGRTKEKERQQ-PLLQLPAEASDEGIVISANEDEPALPRR-ADCAAVGTMGRRRANGSVA
PQERSHNVIEVATDAPLRKPGGYFAAPAQPDPDDQFIIPPELEEEVKEIMKHQQPPPPPP
PPPPP--SQ------------------LHVQPPPRQCPGDQLPDCCDTPL

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---------------------------SGKPHSTGNSERIQLSGMYNVRKGKMHLPVNRW
TRRQVILCGTCLIVSSVKESQTGKMHVLPLIGGKVEEVKKH-QHCLAFSSSGPQSQTYYI
CFDTFTEYLRWLRQASKVASQRISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLRLNP
SVSTTRGLSELQRF-T

PF00560 // ENSGT00440000037833_1_Domain_3 (797, 814)

KLKSLNLSNNNLGDFPLAVCSIPTLTELNVSCNALKSIPAAVGD
MHNLQTLLLDGNFLHSLPN---------YLSLSFNEFTDIPGVLEKLNGMDKLCMSGNCM
ETLSLQALRRMPHIKHVDLRLNVIRRLVV-DEVDFLHHVTQLDLRDNKLCELDATIFNNI
EVLH----------------------C----------------ERNHLVTLKISGYF---
LKALYAFSNELVHLDVYPVPNYLTSMDISRNHLESLPEWVCDSR

PF00560 // ENSGT00440000037833_1_Domain_10 (1065, 1085)

KLEVLDVGHNQLCELP
TRLFCSSSLRKLLSGHNQLGRLPERFERT

PF00560 // ENSGT00440000037833_1_Domain_12 (1110, 1129)

QLEVLDVQHNQLLELPSNLLLKADSLRSLNA
SANKLETLPPATLSEETNS---ILQELYLTNNNL----------------------TDKC
VPLLTGHPHLKILHMAYNRLQSFPA-SKMAK-----------------------------
-----LEE

PF00560 // ENSGT00440000037833_1_Domain_16 (1269, 1288)

LEEIDISGNKLKAIPTTIMNCRRMHTVIAHSNCIEVFPEVMQLVEIKCVDLS
CNELSEITLPENLPPKLQELDLTGNPRLVLDHKTLELLN-NIRCFKIDQPSAG----DAS
GAPAVWSHG

PF00481 // ENSGT00440000037833_1_Domain_18 (1390, 1632)

YTEASGVKNKLCVAALSANNFCDNREALYGVFDGDRNVEVPYLLQCTMSDI
LAEELQKTKSEEEYMINTFIVMQRKLGTAGQKLGGSAVLCHIKHDPMDPGGCFTLTSANV
GKCQTVLCRNGKPLPLSRSYVMSCEEELKRIKQHKAIITED-GKVN--GVTDS-TRILG-
YTFLHPSVVPRPHVQSITLTPQDEFFILGSKGLWDSLSTEEAVEAVRNVPEPLAAAKKLC
TLAQSYGYNDSISAVVVQLNVTEDSFCCCELN---GVPPPSPGIFPQSVNVVIKDRPTDA
LGMPSSSSGMASEISSEISTSEMSSEVGSTASDEPP-QVALNE--NSPAYPNEQRCMLHP
VCLANSFQRQLSS----ATFSSAFSDNGLDSDDEEPIEGVFTNGSRVE------VEVDIH
CSRAKEKQ---L--LHVPVEASDEGIVISANEDETGLSRK-ADYSATGTIGRRRGNGSVA
PQEGSHNLIEVAADAPLRKTGGYFAAPAQPDPDDQFIIPPELEEEVKEIMKQHQEQQQQQ
--Q--------------------------QQQQQRQYQMDQLPDYYDTPL

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-------------------------MEKQDVSKTKKNLGNSQPPIQLYKEYCRSKVLGFQ
EQWQRGLNEWSRKQNEKDKITFACV--LGKPHSSGSSERIQLSGMYNVRKGKM

PF00169 // ENSGT00440000037833_1_Domain_0 (654, 738)

QLPVNRW
TRRHVILCGTCLIVSSVKDSLTGKMHVLPLIGGKVEEVKKH-QHCLAFSSSGPQSQTYYI
CFDTFTEYLRWLRQVSKVASQRISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFIRQNP
SLPAARGLNELQRF-

PF13516 // ENSGT00440000037833_1_Domain_3 (796, 810)

TKLKSLNLSNNHLGDFPLAVCSIPTLTELNVSCNALRAVPASVGA
MHNLHTFLLDGNFLQSLPAELENMHQLSYLGLSFNEFTDIPEVLEKLTAMDKLCMSGNCM
ETLRLQALRRMPHIKHVDLRLNIIRKLVA-DEVEFL

PF13516 // ENSGT00440000037833_1_Domain_8 (937, 952)

QHVTQLDLRDNKLGD

ENSGT00440000037833_1_Linker_8_10 (952, 1043)

LDAMIFNNL
EVLH----------------------C----------------ERNQLVTLSICGYF---
LKALYASSNELVQLDVYPVPNY

PF13855 // ENSGT00440000037833_1_Domain_10 (1043, 1099)

LSYMDVSRNRLENVPEWVFESRKLEVLDIGHNQICDLP
ARLFCNSSLRKLLAGHNQLARLPERLERTSVEVLDVQHNQLVELPPNLLLKADSLRFLNA
SANKLENLPPATLSEETNS---I

PF13855 // ENSGT00440000037833_1_Domain_15 (1164, 1279)

LQELYLTNNNL----------------------TDKC
VPLLTGHPHLKILHMAYNRLQSFPA-SKMAK-----------------------------
-----LEELEEIDISGNKLKAIPTTILNCRRMHTVIAHSNCIEVFPEVMQLPEIKCVDLS
CNELSEVTLPENLPPKLQELDLTGNPRLALDHKTLELLN-NIRCFKIDQPSAG----DAS
GAPAVWSH

PF00481 // ENSGT00440000037833_1_Domain_18 (1389, 1632)

GYTEASGVKNKLCVAALSVNNFCDNREALYGVFDGDRNVEVPYLLQCTMSDI
LAEELQKTKNEEEYMVNTFIVMQRKLGTAGQKLGGAAVLCHIKHDPVDPGGSFTLTSANV
GKCQTVLCRNGKPLPLSRSYVMSCEEELKRIKQHKAIITED-GKVN--GVTES-TRILG-
YTFLHPSVVPRPHVQSVLLTPQDEFFILGSKGLWDSLSIEEAVEAVRNVPDALAAAKKLC
TLAQSYGCHDSVSAVVVQLSVTEDSFCCCELATTGSVPPPSPGIFPPSVNMVIKDRPSDG
LGVPSSSSGMASEISSELSTSEMSSEVGSTASDEPP-SGALND--SSSAYPSEQRCMLHP
VCLSNSFQRQLSS----ATFSSAFSDNGLDSDDEEPIEGVFTNGSRVE------VEVDIH
CSRAKEKEKQQ-HQLQMPAEASDEGIVISANEDEPGLPRK-ADFSSVGTIGRRRANGSVA
PQERSHNVIEVATDAPLRKPGGYFAAPAQPDPDDQFIIPPELEEEVKEIMKHHQEQQ-QQ
PPP------------LP------------QQPLQRQFPTDQLPDCYDTPL

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----------KKGRRGARSGAGAPQTTAGGA-------------------------AAVP
GAGHGANSLLLRRGRLKRNLSAAAAAAVSSCSASASLCTRSLDRKTLLLKHRQVMPLQPS
DRDWVRQQLRRGCLHVFDRHTA----S------------AYLRPVLCTLDTTAG--EVAA
RLLQLGHKGGGVLKVLGQGPGPAGAEASPADLPLTAGGPGPDCNRPQ----DMTGKRGLS
LVQTLDRPRCTARSSARPREAPRASDIAG-------GAAPEGPRP-EEA-A-------AA
AAEAPGG--AP------SKVPPPPTLYVQLHGETTRRLEADEKPLQIQNDYLFQLGFG--
ELWRVQE----EGMDSEIGCLIRFY--VGKPHSTSSSERIQLSGMYNVRKGKMQLPVNRW
TRRQVILCGTCLIVSSVKDSLTGKMHVLPLIGGKVEEVKKH-QHCLAFSSSGPQSQTYYI
CFDTFTEYLRWLRQVSKVASQRISSVDLSCCSLEHLPVNLFYSQDLTHLNLKQNFLRQNS
SLSSTRGLNELQRF-T

PF00560 // ENSGT00440000037833_1_Domain_3 (797, 814)

KLKSLNLSNNHLGDFPLAVCSIPTLAELNVSCNALQAVPAAVGA
MHNLQTFLLDGNFLQSLPAELENMHQLSYLGLSFNEFTDIPEVLEKLTAVDKLCMSGNCM
ETLRLQALRKMPHIKHVDLRLNVIREVIA-DAVDFVQHVTQLDLRDNKLSELDAMIFNNI
EVLH----------------------C----------------ERNQLVTLNICGYF---
LKALYASSNELVQIDVYPVPNYLSYMDVSRNRLENVPEWVCESR

PF00560 // ENSGT00440000037833_1_Domain_10 (1065, 1086)

KLEVLDIGHNQICELP
ARLFCNSSLRKLLAGHNQLARLPERLERTLVEVLDVQHNQLLELPPNLLMKADSLRFLNA
SANKLETLPPATLCEETSS---ILQELYLTNNNL----------------------TDKC
VPLLTGHPHLKILHMAYNRLQSFPA-SKMAK-----------------------------
-----LEELEEIDISGNKLKAIPTTIMNCRRMHTVIAHSNCIEVFPEVMQLPEIKCVDLS
CNELSEVTLPENLPPKLQELDLTGNPRLSLDHKTLELLN-NIRCFKIDQPSAG----DAS
GAPAVWSH

PF00481 // ENSGT00440000037833_1_Domain_18 (1389, 1632)

GYTEASGVKNKLCVAALSVNNFCDNREALYGVFDGDRNVEVPYLLQCTMSDI
LAEELQKTKNEEEYMVNTFIVMQRKLGTAGQKLGGSAVLCHIKHDPVDPGGSFTLTSANV
GKCQTVLCRNGKPLPLSRSYVMSCEEELKRIKQHKAIITED-GKVN--GVTES-TRILG-
YTFLHPSVVPRPHVQSVLLTPQDEFFILGSKGLWDSLSIQEAVEAVRNVPDALAAAKKLC
TLAQSYGCHDSISAVVVQLSVTEDSFCCCELSAGGSVPPPSPGIFPPSVNMVIKDRPPDG
LGVPSSSSGMASEISSELSTSEMSSEVGSTASDEPP-NGALNE--SSPAYPSEQRCMLHP
VCLSNSFQRQLSS----ATFSSAFSDNGLDSDDEEPIEGVFSNGSRVE------VEVDIH
CSRAKEKEKQQ-QVLQVPAEASDEGIVISANEDEPGLPRK-ADFSAVGTIGRRRANGSVA
PQERSHNVIEVAAEAPLRKPGGYFAAPAQPDPDDQFIIPPELEEEVKEIM----------
--------------------------------------------------

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-------------VSLRLNCLLVLV--VGKPHSTGSSERIQLSGMYNVRKGKMHLPVNRW
TRRQVILCGTCLIVSSVKDSVAGKMHVLPLIGGKVEEVKKH-RHCLALSSSGPQSQTYCV
CFDTFTEYLRWLRQVSKVASQRVSSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLRQNP
SLPTARGLSELQRF-T

PF00560 // ENSGT00440000037833_1_Domain_3 (797, 813)

KLKSLNLSNNHLGDFPLAVCDIPTLAELNVSCNALRAVPAAVGA
MRNLQTFLLDGNFLQTLPAELENMHQLSYLGLSFNEFTDFPEVLEKLTAVDKLCMSGNCM
ETLRLQALRKMPHIKHVDLRLNLIRKLVV-DGVDFLPHVTQLDLRDNQLGNLDATVFSGL
EVLH----------------------C----------------ERNQLVALGLCGCV---
LKALHAASNELVQIDVSPVPNYLSYMDVSRNCLENVPEWVCESR

PF00560 // ENSGT00440000037833_1_Domain_10 (1065, 1086)

KLEVLDIGHNQICELP
ARLFCNSGLRKLLAGHNRLARLPERLERTSVEVLDVQHNQLLELPPSLLMKADSLRFLNA
SANKLETLPPAALSEETSS---VLQELYLTNNSL----------------------TDKC
VPLLTGHPHLKILHMAYNRLQSFPA-SKMAK-----------------------------
-----LEELEEIDLSGNKLKAVPTTIMSCRRMHTVAAHSNCIEVFPEVMQLPEIKCVDLS
CNELSEVTLPENLPPKLQELDLTGNPRLALDHRTLELLN-NIRCFKIDQPSAG----DAS
GAPAVWSH

PF00481 // ENSGT00440000037833_1_Domain_18 (1389, 1539)

GYTEASGVKNKLCVAALSVNNFRDNREALYGVFDGDRNVEVPNLLQCTMSDI
LAEELQRSRSGEECMVNTFLVMQRKLGTAGQKLGGAAVLCHIRHDPGDPGGPFTLTSANV
GKCQTVLCRSGEPLPLSKSYAVSCTPELIRDDRSGSTASQSRGAHW--GLRPDGLSTSGQ
AVILAVSQGTRSGAQAVTFQPRRLGFLLGEAGVARRLSGSRGQSCWRGVPDARAAAKKLC
TLAQSYGCRESVSAVVVQLSVPEDSFCCCELA---ALPPRTPRCCP--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

MEPAAAAPAQRLADPTGEDQALAA---------------------AAAEGGRCPDPALSA
AAPSGGN--GGAAREEAPCEAPPGPLPGRAG-GTGRRRRRGA-PQPAAGGAAPVPAAGG-
--GANSLLLKRGRLKRNLSAAAAASSSSSP-----------SSASSAAGGLPASCSASAS
LCTRSLDRKTLLLKH-RQLLQLQPSDRDWVRHQLQRGCVHVFDRHMASSYLRPVLCTLDT
TAAEVAARLLQLGHK----GGGVVKVLGYGPPPAAAPAASDQ----TLDGELG------R
DMEPPPSSGT---VGAVRGPARAPPA-DLPLPGG----------------AWTRCAPRIS
PAPSDSSPGELFA-----GGPGSPPRAPRPA----------SDTESFSLSPSAE--SVSD
RLDPYSSGGGGSSSSSEELEADPA-----------M-------------------PHGPG
RPAQP-RPPSPKTSALLQPKAPTGVDSTG-------VIAGEGPGDDKAMAAAAPDVPLST
--PGRIRETVQ-------KTSSPPSLYVQLHGETTRRLEADEKPLQIQNDYLFQLGFG--
ELWRVQE----EGMDSEIGCLIRFY--AGKPHSTGSSERIQLSGMYNVRKGKM

PF00169 // ENSGT00440000037833_1_Domain_0 (654, 738)

QLPVNRW
TRRQVILCGTCLIVSSVKDSVSGKMHVLPLIGGKVEEVKKH-QHCLAFSSSGPQSQTYYI
CFDTFTEYLRWLRQVSKVASQRISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLRQTP
TLPAARGLGELQRF-TKLKSLNLSNNHLGAFPSAVCSI

PF13855 // ENSGT00440000037833_1_Domain_4 (819, 876)

PTLAELNVSCNALREIPAAVGD
MQNLQTFLLDGNFLQSLPAELESMHQLSYLGLSFNEFTDIPEVLEKLTAVDKLCMAGNCV
ETLRLQALRRMPHIKHVDLRLNILRKLMA-DEVDFV

PF13516 // ENSGT00440000037833_1_Domain_8 (937, 952)

QHVTQLDLRDNKLGDLDAMIFNNI
EVLH----------------------C----------------ERNQLVTLNVCGYF---
LKALYASSNELAQLDVYPVPNYLSYMDVSRNCLESVPEWVCESR

PF00560 // ENSGT00440000037833_1_Domain_10 (1065, 1086)

KLEVLDIGHNQICELP
ARLFCNSSLRKLLAGHNRLARLPERLERTSVEVLDVQHNQITELPPNLLMKADSLRFLNA
SANKLETLPPATLSEETSS---I

PF13855 // ENSGT00440000037833_1_Domain_15 (1164, 1279)

LQELYLTNNCL----------------------TDKC
VPLLTGHPRLKILHMAYNRLQSFPA-SKMAK-----------------------------
-----LEELEEIDISGNKLKAIPTTIMNCRRMHTVIAHSNCIEVFPEVMQLPEVKCVDLS
CNELSEITLPENLPPKLQELDLTGNPRLALDHKSLELLN-NIRCFKIDQPSAG----DTS
GAPAVWSH

PF00481 // ENSGT00440000037833_1_Domain_18 (1389, 1632)

GYTEASGVKNKLCVAALSVNNFRDNREALYGVFDGDRNAEVPYLLQCTMSDI
LAEELQKTKNEEEYMVNTFIVMQRKLGTAGQKLGGAAVLCHIKPDPVDLGGSFTLTSANV
GKCQTVLCRNGKPLSLSRSYIMSCEEERKRIKQHKAIITED-GKVN--GVTES-TRILG-
YTFLHPSVVPRPHVQSVLLTPQDEFFILGSKGLWDSLSIEEAVEAVRNVPDALAAAKKLC
TLAQSYGCHDSISAVVVQLSVTEDSFCCCELSAGGSMPPPSPGIFPPSVNMVIKDRPSDG
LGVPSSSSGMASEISSELSTSEMSSEVGSTASDEPP-SGVLNE--SSPAYPNEQRCMLHP
VCLSNSFQRQLSS----ATFSSAFSDNGLDSDDEEPIEGVFSNGSRVE------VEVDIH
CSRTKEKERQQ-HLLQVPAEASDEGIVISANEDESGLSKK-ADFSAVGTIGRRRANGSVA
PQERSHNVIEVAADAPLRKPGGYFAAPAQPDPDDQFIIPPELEEEVKEIMKHHQEQQQQQ
QQQ--QL---PPPPQPPQ--PQPQ----PQPQPQRHFQMDHLPDCYDTPL

MEPAAAAPAQRLADPAGEDRAPAAAAAAXXXXXXXXXXXXXXXXXXXX-----------X
X--XXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXRRRGA-PQSSAAGAVPVPAAGGG
-GGANSLLLRRGRLKRNLSAAASASSSP-------------SSASSAAGGLPASCSASAS
LCTRSLDRKTLLLKH-RQLLQLQPSDRDWVRHQLQRGCVHVFDRHMASSYLRPVLCTLDT
TASEVAARLLQLGHK----GGGVVKVLGQGLPPAAAPAGSDQ----TADAGLGR------
DVEPPPSSGT---PGAVGVPARAPPA-DLPLPGG----------------AWTHRAPRAS
SAPSDSSPGELFA-----GGPGSPPRAPHPA----------SDTESFSLSPSAE--SVSD
RLDPYSSGGGSSSSEELEAAEPAL-----------GS-----------------------
---TGPRPPSPKTSPSPQPKAPRGVDGTG-------GMAAQGLKEDKAVAAAAPAGPLST
--PGRIRETAQ-------KTTSPPSLYVQFHGETTRRLEADEKPLQIQNDYLFQLGFG--
ELWRVQE----EGMDSEIGCLIRFY--AGKPHSTGSSERIQLSGMYNVRKGKM

PF00169 // ENSGT00440000037833_1_Domain_0 (654, 738)

QLPVNRW
TRRQVILCGTCLIVSSVKDSLSGKMHVLPLIGGKVEEVKKH-QHCLAFSSSGPQSQTYYI
CFDTFTEYLRWLRQVSKVASQRISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLRQNP
TLPAARGLGELQRF-TKLKSLNLSNNHLGAFPSAVCSI

PF13855 // ENSGT00440000037833_1_Domain_4 (819, 876)

PTLAELNVSCNALREVPAAVGA
MQNLQTFLLDGNFLQSLPAELENMHQLSYLGLSFNEFTDIPEVLEKLTAVDKLCMAGNCM
ETLRLQAFRRMPHIKHVDLRLNVLRKLIA-DEVDFV

PF13516 // ENSGT00440000037833_1_Domain_8 (937, 952)

QHVTQLDLRDNKLGDLDAMIFNNI
EVLH----------------------C----------------ERNQLVTLNICGYF---
LKALYASSNELVQLDVYPVPNFLSYMDVSRNCLENVPEWVCESRKLEVLDIGHNQICELP
ARLFCNSSLRKLLAGHNQLARLPERLERTSVEVLDVQHNQLIELPPNLFMKADSLRFLNA
SANKLETLPPATLSEETSS---I

PF13855 // ENSGT00440000037833_1_Domain_15 (1164, 1279)

LQELYLTNNSL----------------------TDKC
VPLLTGHPRLKILHMAYNRLQSFPA-SKMAK-----------------------------
-----LEELEEIDISGNKLKAIPTTIMNCRRMHTVIAHSNCIEVFPEVMQLPEVKCVDLS
CNELSEISLPENLPPKLQELDLTGNPRLALDHRSLELLN-NIRCFKIDQPSAG----DAS
GAPAVWSH

PF00481 // ENSGT00440000037833_1_Domain_18 (1389, 1632)

GYTEASGVKNKLCVAALSVNNFRDNREALYGVFDGDRNVEVPYLLQCTMSDI
LAEELQRTKNDDEYMVNTFIVMQRKLGTAGQKLGGAAVLCHIKHDPVDLGGSFTLTSANV
GKCQTVLCRNGKPLPLSRSYTMSCEEELMRIKQHKAIVTED-GKVN--GVTES-TRILG-
YTFLHPSVVPRPHVQSVLLTPQDEFFILGSKGLWDSLSIEEAVEAVRNVPDSLAAAKKLC
TLAQSYGCHDSISAVVVQLSVTEDSFCCCELSAGGSMPPPSPGIFPPSVNMVIKDRPSDG
LGVPSSSSGMASEISSELSTSEMSSEVGSTASDEPP-SGVLNE--NSPAYPSEQRCMLHP
VCLSNSFQRQLSS----ATFSSAFSDNGLDSDDEEPIEGVFSNGSRVE------VEVDIH
CSRAKEKERQQ-YLLQVPAEASDEGIVISANEDEAGLSRK-ADFSAVGTIGRRRANGSVA
PQERSHNVIEVATDAPLRKPGGYFAAPAQPDPDDQFIIPPELEEEVKEIMKHHQEQQQQQ
A---PPP---PSQPQP---------QAQPQPQPQRQLQVNHLPDCYDTPL

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------A-DLLLPRGPGG--------------RTICASRAS
PAPTDSFFGEPGARRALDG--A--AAG------------AASDTESFSLSPSAE--SVSD
RLDPYSSGSG--------------SSSSCEELEGDPAPAPAPAPAPALALPGR------C
AQ--PRPPSPTASPPPLQPKGPRGVDGPG-------GAARDRPREEKAAAAAA-------
PGRPP---SAP------EKAPPPPTLYVQLHGEATRRLEADEKPLQIQNDYLFQLGFG--
ELWRVQE----EGMDSEVGCLIRFY--AGKPHSTGSSERIQLSGMYNVRKGKMQLPVNRW
TRRQVILCGTCLIVSSVKDSLTGKMHVLPLIGGKVEEVKKH-QHCLAFSSSGPQSQTYYI
CFDTFTEYLRWLRQVSKVASQRISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLRQNP
CLPTARGLNELQRF-T

PF00560 // ENSGT00440000037833_1_Domain_3 (797, 814)

KLKSLNLSNNHLGEFPL

ENSGT00440000037833_1_Linker_3_4 (814, 819)

AVCNI

PF13855 // ENSGT00440000037833_1_Domain_4 (819, 876)

PTLTELNVSCNALRAVPAAVGV
MHNLQTFLLDGNFLQALPPELENMHQLSYLGLSFN

ENSGT00440000037833_1_Linker_4_8 (876, 936)

EFTDIPEILEKLTAVDKLCMSGNCM
ETLRLEALRKMPHIKHVDLRLNVIRKLIA-DEVDF

PF13516 // ENSGT00440000037833_1_Domain_8 (936, 955)

LQHVTQLDLRDNKLGDLDAMIFNNI
EVLH----------------------C----------------ERNQLVTLNICGYF---
LKALYAASNELVQLDVYPVPNYLSYMDVSRNCLENVPEWVCESR

PF00560 // ENSGT00440000037833_1_Domain_10 (1065, 1086)

KLEVLDIGHNQICELP
ARLFCHSSLRKLLAGHNQLTRLPERLERTSVEVLDVQHNQLLELPPNLLMKADSLRFLNA
SANKLETLPPATLSEETNS---ILQELYLTNNNL----------------------TDKC
VPLLTGHPHLKILHMAYNRLQSFPA-SKMAK-----------------------------
-----LEELEEIDISGNKLKAIPTTIMNCRRMHTMIAHSNCIEVFPEVMQLPEIKCVDLS
CNELSEVTLPENLPPKLQELDLTGNPRLALDHKTLELLN-NIRCFKIDQPSTG----DAS
GAPAVWSH

PF00481 // ENSGT00440000037833_1_Domain_18 (1389, 1631)

GYTEASGVKNKLCVAALSVNNFCDNREALYGVFDGDRNVEVPYLLQCTMSDI
LAEELQKTKNEEEYMVNTFIVMQRKLGTAGQKLGGAAVLCHIKHDPVDPGGSFTLTSANV
GKCQTVLCRNGKPLPLSRSYVMSCEEERKRIKQHKAIITED-GKVN--GVTES-TRILG-
YTFLHPSVVPRPHVQSVPLTPQDEFFILGSKGLWDSLSSEEAVAAVRHVPDALAAAKKLC
TLAQSYGCHDSLSAVVVQLSVTEDSFCCCELGAGGAGPPPSPGIFPPSVSMVIKDRPADA
LGVPSSSSGMASEMSSELSTSEMSSEVGSTASDEPP-SGALAE--SSPAYASEPRCTLHP
GGLASAFQRQLSS----ATFSSAFSDNGLDSDDEEPIEGVFSNGSRVE------VEVDIH
CGRAREKEA-Q-RLLHVPAEASDEGIVTSANEDEPGLPRR-PDG-AAGTIGRRRPNGSVA
PQERSHNVIEVAADAPLRKPGGYFAAPAQPDPEDQFIIPPELEEEVKEMMKQQQQPA---
-------GL------------------QP---APRPSPGDP---------

MEPAAAATVQRLPETSREDRAPALAA------------------AAAGGGGRSPGSPLPS
GTPTMQFLPGGGAGEEAPAGPLPGAPCGGGGEGAVPRRRRGT-TLLAANGAPPAPGAGS-
--GANSLLLRRGRLKRNLSAAATSSSS------SNSSAAAAASHSSSAASLAASGSASAS
LCTRSLDRKTLLLKH-RQMMQLQPSDRDWVRHQLQRGCVHVFDRHMASTYLRPVLCTLDT
TAGEVAARLLQLGHKGGA-GGVVMKVVGRGPGPASARRPAAGA---SPEAGPELTAPRSP
ERPPRKNGLGELVEPAVGGKPRTPPG-DLPLRSDAGR--------------FVGCLTHGS
PAPSDLSPGDVY-----AGVPGSLLGDLRP---------VASDTESFSLSPSAE--SVSD
RLDPYSSGGGGGSSSSEELEADSAPTPTEG----SGLALPPGCSAPS-------------
--LPPLHPSSLAGPAQSPPKTPKGVDSRG-------GVAQDGPLEK------APGGVVSP
LSPPGHGG--------AADKPPMPTLYVQFHGETTRRLEAHEKPLQIQNDYLFQLGFR--
ELWRVQE----EGMDSEIGCLIRFY--AGKPHSTGSSERIQLSGMYNVRKGKMQLPVNRW
TRRQVILCGTCLIVSSVKDSLTGKMHVLPLIGGKXXXXXXX-XXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXVASQ

PF00560 // ENSGT00440000037833_1_Domain_1 (742, 760)

RISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLRQNP
SSPSNRGLGELKRF-T

PF00560 // ENSGT00440000037833_1_Domain_3 (797, 818)

KLKSLNLSNNHLGDFPLAVCN

ENSGT00440000037833_1_Linker_3_5 (818, 820)

IP

PF00560 // ENSGT00440000037833_1_Domain_5 (820, 841)

TLTELNVSCNALRTVPTAAGD

ENSGT00440000037833_1_Linker_5_4 (841, 843)

MH

PF00560 // ENSGT00440000037833_1_Domain_4 (843, 864)

NLQTFLLDGNYLQSLPAELEN

ENSGT00440000037833_1_Linker_4_6 (864, 866)

MQ

PF00560 // ENSGT00440000037833_1_Domain_6 (866, 887)

QLSYLGLSFNEFTDIPKVLEKLTAVDKLCMSGNCM
ETLNLQSLRRMPHIKHVDLRLNVIRKLMV-QEVDFLP

PF00560 // ENSGT00440000037833_1_Domain_8 (938, 960)

HVTQLDLRDNKLGDLDATVFNNL
EVLH----------------------C----------------ERNQLVTLNVCGYL---
LKALYASSNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX

PF00560 // ENSGT00440000037833_1_Domain_10 (1065, 1087)

KLEVLDVCHNQIRELP
ARLFYN

ENSGT00440000037833_1_Linker_10_11 (1087, 1088)

S

PF00560 // ENSGT00440000037833_1_Domain_11 (1088, 1106)

SLRKLLVGHNQLTRLPER

ENSGT00440000037833_1_Linker_11_12 (1106, 1110)

LERT

PF00560 // ENSGT00440000037833_1_Domain_12 (1110, 1128)

QVEVLDVQHNQLVELPPN

ENSGT00440000037833_1_Linker_12_13 (1128, 1134)

LLMKAD

PF00560 // ENSGT00440000037833_1_Domain_13 (1134, 1156)

SLRFLNA
SANKLETIPPAALSEETSS---ILQELYLTNNHL----------------------TDKC
VPLLIGHPHLKILHMAYNRLQSFPA-XXXXX-----------------------------
-----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXCVDLS
CNELSEVTLPENLPS

PF00560 // ENSGT00440000037833_1_Domain_17 (1336, 1358)

KLQELDLTGNPRLALDHKTLEL

ENSGT00440000037833_1_Linker_17_18 (1358, 1386)

LN-NIRCFKIDQPSAG----DAS
GAPAV

PF00481 // ENSGT00440000037833_1_Domain_18 (1386, 1632)

WSHGYTEASGVKNKLCVAALSANNFCDNREALYGVFDGDRNVEVPYLLQCTMSDI
LAEELQKTKNEEEYMVNTFIVMQRKLGTAGQKLGGSAVLCHIKHDPVDPGGYFTLTSANV
GKCQTVLCRNGRPLPLSKSYIMSCEEELKRIKQHKAIITED-GKVN--GVTES-TRILG-
YTFLHPSVVPRPHVQSVTLTPQDEFFILGSKGLWDSLSIEEAIEAVRNVPDALAAAKKLC
TLAQSYGCSDSISAVVVQLNVTEDSFCCCELGG-SGVPPPSPGIFPPSVNVVIKDRPSDG
LGVPSSSSGMASEISSEISTSEMSSEVGSTASDEPP-PGVLSE--SSPAYPSEQRCMLHP
VCLSSSF-----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

MEPAAAATVQRLPELGREDRASAPAAAAAAAAA---AAAAAAALAAAAGGGRSPEPALTP
AAPSGGNGSGSGAREEAPGEAPPGPLPGRAG-GAGRRRRRGA-PQPIAGGAAPVPGAGG-
--GANSLLLRRGRLKRNLSAAAAAASS------SSSSSAAAASHSPGAAGLPASCSASAS
LCTRSLDRKTLLLKH-RQTLQLQPSDRDWVRHQLQRGCVHVFDRHMASTYLRPVLCTLDT
TAGEVAARLLQLGHK----GGGVVKVLGQGPGAAAAREPAEP----PPEAGPRLAPPEPR
DSEVPPARSA---PGAFGGPPRAPPA-DLPLPVGGP-------------GGWSR---RAS
PAPSDSSPGEPFV-----GGPVSSPRAPRPVV---------SDTESFSLSPSAE--SVSD
RLDPYSSGGG-SSSSSEELEADA-------------ASAPTGVPGQ-PR--------RPG
HPAQPLPLPQTASSPQPQQKAPRAIDSPG-------GAVREGSCEEKAAAAVAPGGLQST
--PGRSGVTAEKAPPPP----PPPTLYVQLHGETTRRLEAEEKPLQIQNDYLFQLGFG--
ELWRVQE----EGMDSEIGCLIRFY--AGKPHSTGSSERIQLSGMYNVRKGKM

PF00169 // ENSGT00440000037833_1_Domain_0 (654, 738)

QLPVNRW
TRRQVILCGTCLIVSSVKDSLTGKMHVLPLIGGKVEEVKKH-QHCLAFSSSGPQSQTYYI
CFDTFTEYLRWLRQVSKVASQRISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLRQNP
SLPAARGLNELQRF-

PF13516 // ENSGT00440000037833_1_Domain_3 (796, 810)

TKLKSLNLSNNHLG

ENSGT00440000037833_1_Linker_3_4 (810, 819)

DFPLAVCSI

PF13855 // ENSGT00440000037833_1_Domain_4 (819, 876)

PTLAELNVSCNALRSVPAAVGV
MHNLQTFLLDGNFLQSLPAELENMKQLSYLGLSFNEFTDIPEVLEKLTAVDKLCMSGNCV
ETLRLQALRKMPHIKHVDLRLNVIRKLIA-DEVDFL

PF13516 // ENSGT00440000037833_1_Domain_8 (937, 952)

QHVTQLDLRDNKLGDLDAMIFNNI
EVLH----------------------C----------------ERNQLVTLDICGYF---
LKALYASSNELVQLDVYPVPNYLSYMDVSRNRLENVPEWVCESRKLEVLDIGHNQICELP
ARLFCNSSLRKLLAGHNQLARLPERLERTSVEVLDVQHNQLLELPPNLLMKADSLRFLNA
SANKLESLPPATLSEETNS---I

PF13855 // ENSGT00440000037833_1_Domain_15 (1164, 1279)

LQELYLTNNSL----------------------TDKC
VPLLTGHPHLKILHMAYNRLQSFPA-SKMAK-----------------------------
-----LEELEEIDLSGNKLKAIPTTIMNCRRMHTVIAHSNCIEVFPEVMQLPEIKCVDLS
CNELSEVTLPENLPPKLQELDLTGNPRLVLDHKTLELLN-NIRCFKIDQPSTG----DAS
GAPAVWSH

PF00481 // ENSGT00440000037833_1_Domain_18 (1389, 1632)

GYTEASGVKNKLCVAALSVNNFCDNREALYGVFDGDRNVEVPYLLQCTMSDI
LAEELQKTKNEEEYMVNTFIVMQRKLGTAGQKLGGAAVLCHIKHDPVDPGGSFTLTSANV
GKCQTVLCRNGKPLPLSRSYIMSCEEELKRIKQHKAIITED-GKVN--GVTES-TRILG-
YTFLHPSVVPRPHVQSVLLTPQDEFFILGSKGLWDSLSVEEAVEAVRNVPDALAAAKKLC
TLAQSYGCHDSISAVVVQLSVTEDSFCCCELSAGGAVPPPSPGIFPPSVNMVIKDRPSDG
LGVPSSSSGMASEISSELSTSEMSSEVGSTASDEPP-PGALSE--NSPAYPSEQRCMLHP
ICLSNSFQRQLSS----ATFSSAFSDNGLDSDDEEPIEGVFTNGSRVE------VEVDIH
CSRAKEKEKQQ-HLLQVPAEASDEGIVISANEDEPGLPRK-ADFSAVGTIGRRRANGSVA
PQERSHNVIEVATDAPLRKPGGYFAAPAQPDPDDQFIIPPELEEEVKEIMKHHQEQQ---
QQQQ-PP---PP---P---------QL--QPQLPRHYQLDQLPDYYDTPL

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-APSDSIPGERFAGGPASPPGA--PRP------------LDSDTESFSLSPSAE--SVSD
RLDPYSSGSGG-------------SSSSSEELEADPAPAAPGAPGSSR-------HAGCP
AQ--FAQLSPSASPPRLQQKSPRGVDGSG-------GVLRDGPRREKAAAVVAPGGPQGT
PGRSG---ATL------EKTPHPPTLYVQLHGETTRRLEADEKPLQVQNDYLFQLGFG--
ELWRVQE----EGMDSEIGCLIRFY--AGKPHSTGSSER

PF00169 // ENSGT00440000037833_1_Domain_0 (640, 740)

IQLSGMYNVRKGKMQLPVNRW
TRRQVILCGTCLIVSSVKDSLTGKMHVLPLIGGKVEEVKKH-QHCLAFSSSGPQSQTYYI
CFDTFTEYLRWLRQVSKVA

ENSGT00440000037833_1_Linker_0_1 (740, 742)

SQ

PF00560 // ENSGT00440000037833_1_Domain_1 (742, 760)

RISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLRQNP
SLPAARGLNELQRF-T

PF00560 // ENSGT00440000037833_1_Domain_3 (797, 818)

KLKSLNLSNNHLGEFPLAVCSIPTLAELNVSCNALRAVPAAVGA
MH

PF00560 // ENSGT00440000037833_1_Domain_4 (843, 864)

NLQTFLLDGNFLRSLPAELEN

ENSGT00440000037833_1_Linker_4_6 (864, 866)

MH

PF00560 // ENSGT00440000037833_1_Domain_6 (866, 887)

QLSYLGLSFNEFTDIPEVLEKLTAVDKLCMSGNCM
ETLRLQALRKMPHIKHVDLRLNVIRRLIA-DEVDFVQ

PF00560 // ENSGT00440000037833_1_Domain_8 (938, 960)

HVTQLDLRDNKLGDLDAVIFNNI
EVLH----------------------C----------------ERNQLVTLNICGYF---
LKALYASCNELVQLDVYPVPNYLSYMDVSRNRLESVPEWVCESQ

PF00560 // ENSGT00440000037833_1_Domain_10 (1065, 1087)

KLEVLDIGHNQICELP
ARLFCNSSLRKLLAGYNQLARLPERLERT

PF00560 // ENSGT00440000037833_1_Domain_12 (1110, 1128)

SVEVLDVQHNQLLELPPN

ENSGT00440000037833_1_Linker_12_13 (1128, 1134)

LLMKAD

PF00560 // ENSGT00440000037833_1_Domain_13 (1134, 1156)

SLRFLNA
SANKLETLPPATLSEETSS---ILQELYLTSNNL----------------------TDKC
VPLLTGHP

PF00560 // ENSGT00440000037833_1_Domain_15 (1209, 1266)

HLKILHMAYNRLQSFPA-SKMAK-----------------------------
-----

ENSGT00440000037833_1_Linker_15_16 (1266, 1268)

LE

PF00560 // ENSGT00440000037833_1_Domain_16 (1268, 1289)

ELEEIDVSGNKLKAIPTTIMNCRRMHTVTAHSNCIEVFPEVMQLPEIKXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-NIRCFKIDQPSAG----DAS
GAPAV

PF00481 // ENSGT00440000037833_1_Domain_18 (1386, 1632)

WSHGYTEASGVKNKLCVAALSVNNFCDNREALYGVFDGDRNVEVPYLLQCTMSDI
LAEELQKTKNEEEYMVNTFIVMQRKLGTAGQKLGGAAVLCHIKHDPADPGGSFTLTSANV
GKCQTVLCRNGKPLPLSRSYVMSCEEELKRIKQHKAIITEX-XXXX--XXXXX-XXXXX-
XXXXXXXXXXXXXXQSVLLTPQDEFFILGSKGLWDSLSVEEAVEAVRNVPDALAAAKKLC
TLAQSYGCHDSISAVVVQLSVTEDSFCCCELSAGGTVPPPSPGIFPTSVNMVIKDRPADG
LTMPSSSSGMASEISSELSTSEMSSEVGSTASDEPP-SGALNE--SSPACPSEQRCMLHP
VCLSSSFQRQLSS----ATFSSAFSDNGLDSDDEEPIEGVFTNGSRVE------VEVDIH
CSRAKEKEKQQ-HLLQVPAEASDEGIVISANEDESGLPRK-TDFSAVGTIGRRRANGSVA
PQER-HNVIEVAAGAPLRRAESYFAAPAHPDPNDQFIIPP--------------------
--------------------------------------------------

MEPAAAATAQRLPETSREDQAPAAAA--------------AAAAAAGAGGGRSTEPALTL
AAPSG------GARDEAPGEAQPGPLPSRAG-GTGRRRRRGA-PQPTASGAAPVPGAGG-
--GANSLLLRRGRLKRNLSAAAAASSSSSSSSSSSSSSAAAASYSPSAAGLPASCSASAS
LCTRSLDRKTLLLKH-RQMLQLQPSDRDWVRHQLQRGCVHVFDRHMASTYLRPVLCTLDT
TAGEVAARLLQVGHK----GGGVVKVLGKGPPDAGSRLP----------------TAEPR
DLGLQRGRNGLAAV---GGSSRAPPA-DLPLPSARDG--------------WESHASRAS
PAPSDSSPGEPGASRPLDC--A--ATG------------RSSDTESFSLSPSAE--SVSD
RLDPYSSGGG--------------SSSSSEELEIDSAPALMGAPGQ-PRLPGRSAHPRHG
AG--ARPPSPLVSPPPSQPKASRGVEGPV-------AAALDPPREENVVAAAALGRPQST
SGGDG---ATS------EKAPPPPTLYVQLHGETTRRLEADEKPLQIQNDYLFQLGFG--
ELWRVQE----EGMDSEIGCLIRFY--AGKPHSIGSSERIQLSGMYNVRKGKM

PF00169 // ENSGT00440000037833_1_Domain_0 (654, 738)

QLPVNRW
TRRQVILCGTCLIVSSVKDSLTGKMHVLPLIGGKVEEVKKH-QHCLAFSSSGPQSQTYYI
CFDTFTEYLRWLRQVSKVASQRISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLRQNP
SLPTARGLSELQRF-

PF13516 // ENSGT00440000037833_1_Domain_3 (796, 810)

TKLKSLNLSNNHLGDFPLAVCNIPTLAELNVSCNALQTVPAAVGV
MHNLQTFLLDGNFLQTLPAELENIHQLSYLGLSFNEFTDIPEVLEKLTAVDKLCMSGNCM
ETLRLQALRKMPHIKHVDLRLNLIRKLIA-DEVDFL

PF13516 // ENSGT00440000037833_1_Domain_8 (937, 954)

PHVTQLDLRDNKLGDLDAMVFNNI
EVLH----------------------C----------------ERNQLVTLNICGYF---
LKALYASSNELVQLDVYPVPNYLSYMDVSRNRLENVPEWVCEGRKLEVLDIGHNQICELP
ASLFCNSSLRKLLAGHNQLTRLPERLERTSVEVLDVQHNQLLELPPNLLMKADSLRFLNA
SANKLETLPPATLSEETNS---I

PF13855 // ENSGT00440000037833_1_Domain_15 (1164, 1279)

LQELYLTNNNL----------------------TDKC
VHLLTGHPRLKILHMAYNRLQSFPA-SKMAK-----------------------------
-----LEELEEIDISGNKLKAIPTTIMNCRRMHTVIAHSNCIEVFPEVMQLPEIKCVDLS
CNELSEVTLPENLPPKLQELDLTGNPRLALDHKTLELLN-NIRCFKIDQPSAG----DAS
GAPAVWSH

PF00481 // ENSGT00440000037833_1_Domain_18 (1389, 1632)

GYTEASGVKNKLCVAALSVNNFCDNREALYGVFDGDRNVEVPYLLQCTMSDI
LAEELQKTKNEEEYMVNTFIVMQRKLGTAGQKLGGAAVLCHIKHDPVDPGGPFTLTSANV
GKCQTVLCRNGKPLPLSRSYLMSSEEELKRIKRHKAIITED-GKVN--GVTES-TRILG-
YTFLHPSVVPRPHVQSVPLTPQDEFFILGSKGLWDSLSIEEAVGAVRNVPDALAAAKKLC
TLAQSYGCHDSISAVVVQLSVTEDSFCCCELSAGGA-PPPSPGIFPPSVSMVIKDRPADG
LGVPSSSSGMASEISSELSTSEMSSEVGSTASDEP--PGALAE--SGPAYPSEPRCTLHP
VCLSNSFQRQLSS----ATFSSAFSDNGLDSDDEEPIEGVFSNGSRVE------VEVDIH
CGRAKEK--QQ-HLLQVPAEASDEGIVISANEDESGLPRK-ADLATVGTMGRRRANGSVA
PQERSHNVIEVATDAPLRKPGGYFAAPAQPDPDDQFIIPPELEEEVKEIMKHHQQQ----
----QPPPQ------------------LHLQQPQRQCPVDQLPDYCDTPL

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------XT-------
PGGNG---AAS------EKAPPPPTLYVQLHGETTRRLEADEKPLQIQNDYLFQLGFG--
ELWRVQE----EGMDSEIGCLIRFY--AGKPHSTGSSERIQLSGTY

PF00169 // ENSGT00440000037833_1_Domain_0 (647, 740)

NVRKGKMQLPVNRW
TRRQVILCGTCLIVSSVKDSLTGKMHVLPLIGGKVEEVKKH-QHCLAFTSSGPQSQTYYI
CFDTFTEYLRWLRQVSKIA

ENSGT00440000037833_1_Linker_0_1 (740, 742)

SQ

PF00560 // ENSGT00440000037833_1_Domain_1 (742, 760)

RISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLRQNP
CLLAARGLNELQRF-T

PF00560 // ENSGT00440000037833_1_Domain_3 (797, 818)

KLKSLNLSNNHLGDFPLAVCN

ENSGT00440000037833_1_Linker_3_5 (818, 820)

IP

PF00560 // ENSGT00440000037833_1_Domain_5 (820, 841)

TLTELNVSCNALRAVPAAVGV

ENSGT00440000037833_1_Linker_5_4 (841, 843)

MH

PF00560 // ENSGT00440000037833_1_Domain_4 (843, 864)

NLQTFLLDGNFLQALPPELEN

ENSGT00440000037833_1_Linker_4_6 (864, 866)

MH

PF00560 // ENSGT00440000037833_1_Domain_6 (866, 887)

QLSYLGLSFNEFADIPEVLEKLTAVDKLCMSGNCM
ETLRLQALRKMPHIKHVDLRLNVIRKLIA-DEVDFLQHVTQLDLRDNKLGDLDTMIFNNI
EVLH----------------------C----------------ERNQLVTLNICGYF---
LKALYAASNELVQLDVFPVPNYLSYMDVSRNCLENVPEWVCESR

PF00560 // ENSGT00440000037833_1_Domain_10 (1065, 1087)

KLEVLDVGHNQICELP
ARLFCN

ENSGT00440000037833_1_Linker_10_11 (1087, 1088)

S

PF00560 // ENSGT00440000037833_1_Domain_11 (1088, 1106)

SLRKLLAGHNQLTRLPER

ENSGT00440000037833_1_Linker_11_12 (1106, 1110)

LERT

PF00560 // ENSGT00440000037833_1_Domain_12 (1110, 1132)

SVEVLDVQHNQLLELPPSLLMK

ENSGT00440000037833_1_Linker_12_13 (1132, 1134)

AN

PF00560 // ENSGT00440000037833_1_Domain_13 (1134, 1156)

SLRFLNA
SANKLETLPPATLSEETNS---ILQELYLTNNNL----------------------TDKC
VPLLTGHP

PF00560 // ENSGT00440000037833_1_Domain_15 (1209, 1266)

HLKILHMAYNRLQSFPA-SKMAK-----------------------------
-----

ENSGT00440000037833_1_Linker_15_16 (1266, 1268)

LE

PF00560 // ENSGT00440000037833_1_Domain_16 (1268, 1289)

ELEEIDISGNKLKAIPTTIMN

ENSGT00440000037833_1_Linker_16_17 (1289, 1336)

CRRMHTMIAHSNCIEVFPEVMQLPEIKCVDLS
CNELSEVTLPENLPP

PF00560 // ENSGT00440000037833_1_Domain_17 (1336, 1358)

KLQELDLTGNPRLVLDHKTLEL

ENSGT00440000037833_1_Linker_17_18 (1358, 1386)

LN-NIRCFKIDQPSAG----DAS
GAPAV

PF00481 // ENSGT00440000037833_1_Domain_18 (1386, 1633)

WSHGYTEASGVKNKLCVAALSVNNFCDNREALYGVFDGDRNVEVPYLLQCTMSDI
LAEELQKTKNEEEYMVNTFIVMQRKLGTAGQKLGGAAVLCHIKHDPMDPGGSFTLTSANV
GKCQTVLCRNGKPLPLSRSYVMSCEEEWKRIKQHKAIITED-GKVN--GVTES-TRILG-
YTFLHPSVVPRPHVQSVPLTPQDEFFILGSKGLWDSLSGEEAVAAVRPVPDALAAAKKLC
TLAQSYGCRD-LSAVVVQLSVTEDSFCCCELGAGGAGPPPSPGIFPPSVSMVIKERPADA
LGVPSSSSGLASEMSSELSTSEMSSEVGSTASDEPP-PGALAE--SSPAYASEPRCMLHP
VGLASSFQRQLSS----ATFSSAFSDNGLDSDDEEPIEGVFSNGSRVEXXXXXEVEVDIH
CSRAKEKEQ-Q-RPLHAPAEASDEGIVISANEDEPGLPRR-ADAAATGTIGRRRANGSVA
PQERSHNVIEVAADAPLRKPGGYFAAPAQPDPEDQFIIPPELEEEVKEMMKKQQP-----
--------------------------------PARPCPGDPLP-------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------NKNCRFGVGGGALS-
--IGRLGAVVHACNPSTSGGRDHPGQYRET-----------LSLLKIQKLAGHGVRIS--
AMQMSRK----RVHFKRITCLLVFI--SGKPHSTGSSERIQLSGMYNVRKGKM

PF00169 // ENSGT00440000037833_1_Domain_0 (654, 738)

QLPVNRW
TRRQVILCGTCLIVSSVKDSLTGKMHVLPLIGGKVEEVKKH-QHCLAFSSSGPQSQTYYI
CFDTFTEYLRWLRQVSKVASQRISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLRQNP
SLPAARGLNELQRF-

PF13516 // ENSGT00440000037833_1_Domain_3 (796, 810)

TKLKSLNLSNNHLG

ENSGT00440000037833_1_Linker_3_4 (810, 819)

DFPLAVCSI

PF13855 // ENSGT00440000037833_1_Domain_4 (819, 876)

PTLAELNVSCNALRSVPAAVGV
MHNLQTFLLDGNFLQSLPAELENMKQLSYLGLSFNEFTDIPEVLEKLTAVDKLCMSGNCM
ETLRLQALRKMPHIKHVDLRLNVIRKVIA-DEVDFL

PF13516 // ENSGT00440000037833_1_Domain_8 (937, 952)

QHVTQLDLRDNKLGDLDAMIFNNI
EVLH----------------------C----------------ERNQLVTLDICGYF---
LKALYASSNELVQLDVYPVPNYLSYMDVSRNRLENVPEWVCESR

PF00560 // ENSGT00440000037833_1_Domain_10 (1065, 1086)

KLEVLDIGHNQICELP
ARLFCNSSLRKLLAGHNQLARLPERLERTLVEVLDVQHNQLLELPPNLLMKADSLRFLNA
SANKLESLPPATLSEETNS---I

PF13855 // ENSGT00440000037833_1_Domain_15 (1164, 1279)

LQELYLTNNSL----------------------TDKC
VPLLTGHPHLKILHMAYNRLQSFPA-SKMAK-----------------------------
-----LEELEEIDLSGNKLKAIPTTIMNCRRMHTMIAHSNCIEVFPEVMQLPEIKCVDLS
CNELSEVTLPENLPPKLQELDLTGNPRLVLDHKTLELLN-NIRCFKIDQPSTG----DAS
GAPAVWSH

PF00481 // ENSGT00440000037833_1_Domain_18 (1389, 1632)

GYTEASGVKNKLCVAALSVNNFCDNREALYGVFDGDRNVEVPYLLQCTMSDI
LAEELQKTKNEEEYMVNTFIVMQRKLGTAGQKLGGAAVLCHIKHDPVDPGGSFTLTSANV
GKCQTVLCRNGKPLPLSRSYIMSCEEELKRIKQHKAIITED-GKVN--GVTES-TRILG-
YTFLHPSVVPRPHVQSVLLTPQDEFFILGSKGLWDSLSVEEAVEAVRNVPDALAAAKKLC
TLAQSYGCHDSISAVVVQLSVTEDSFCCCELSAGGAVPPPSPGIFPPSVNVVIKDRPSDG
LGVPSSSSGMASEISSELSTSEMSSEVGSTASDEPP-PGALSE--NSPAYPSEQRCMLHP
ICLA--------------TFSSAFSDNGLDSDDEEPIEGVFTNGSRVE------VEVDIH
CSRAKEKEKQQ-HLLQVPAEASDEGIVISANEDEPGLPRK-ADFSAVGTIGRRRANGSVA
PQERSHNVIEVATDAPLRKPGGYFAAPAQPDPDDQFIIPPELEEEVKELMKHHQEQQQ--
QQQQ-PP---PP---P---------QL--QPQLPRHYQLDQLPDYYDTPL

MEPAAAATAQRLPEPGREDGASAPAAAAAAA-----------------------------
--------------------------XXXXG-GTGRRRRRGA-PLPNAGGAAPVPGAGGG
GGGANSLLLRRGRLKRNLSAAAAAASSS-----SSSSLAAAALHSPSAAGLPASCSASAS
LCTRSLDRKTLLLKH-RQTLQLQPSDRDWVRHQLQRGCVHVFDRHMASTYLRPVLCTLDT
TAGEVAARLLQLGHK----GGGVVKVLGQGPGAXXXXXX---------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------XXXP---PP----PPPTLYVQLHGETTRRLEAEEKPLQIQNDYLFQLGFG--
ELWRVQE----EGMDSEIGCLIRFY--AGKPHSSGSSERIQLSGMYNVRKGKM

PF00169 // ENSGT00440000037833_1_Domain_0 (654, 738)

QLPVNRW
TRRQVILCGTCLIVSSVKDSLTGKMHVLPLIGGKVEEVKKH-QHCLAFSSSGPQSQTYYI
CFDTFTEYLRWLRQVSKVASQRISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLRQNP
SLPAARGLNELQRF-

PF13516 // ENSGT00440000037833_1_Domain_3 (796, 810)

TKLKSLNLSNNHLG

ENSGT00440000037833_1_Linker_3_4 (810, 819)

DFPLAVCNI

PF13855 // ENSGT00440000037833_1_Domain_4 (819, 876)

PTLAELNVSCNALRSVPADVGV
MHNLQTFLLDGNFLQSLPADLENMKQLSYLGLSFNEFTDIPEVLEKLTAVDKLCMSGNCM
ETLRLQALRKMPHVKHVDLRLNVIRKLIA-DEVDFL

PF13516 // ENSGT00440000037833_1_Domain_8 (937, 952)

QHVTQLDLRDNKLGD

ENSGT00440000037833_1_Linker_8_10 (952, 1043)

LDAMIFNNI
EVLH----------------------C----------------ERNQLVTLDICGYF---
LKALYASSNELVQVDVYPVPNY

PF13855 // ENSGT00440000037833_1_Domain_10 (1043, 1099)

LSYMDVSRNRLENVPEWVCESRKLEVLDIGHNQISELP
ARLFCNSSLRKLLAGHNQLARLPERLERTSVEVLDVQHNQLQELPPNLLMKADSLRFLNA
SANKLESLPPATLSEETNS---I

PF13855 // ENSGT00440000037833_1_Domain_15 (1164, 1279)

LQELYLTNNSL----------------------TDKC
VPLLTGHPHLKILHMAYNRLQSFPA-SKMAK-----------------------------
-----LEELEEIDLSGNKLKAIPTTIMNCRRMHTVIAHSNCIEVFPEVMQLPEIKCVDLS
CNELSEVTLPENLPPKLQELDLTGNPRLVLDHKTLELLN-NIRCFKIDQPSTG----DAS
GAPAVWSH

PF00481 // ENSGT00440000037833_1_Domain_18 (1389, 1632)

GYTEASGVKNKLCVAALSVHNFCDNREALYGVFDGDRNVEVPYLLQCTMSDI
LAEELQKTKNEEEYMVNTFIVMQRKLGTAGQKLGGAAVLCHIKHDPVDPGGSFTLTSANV
GKCQTVLCRNGKPLPLSRSYVMSCEEELKRIKQHKAIITED-GKVN--GVTES-TRILG-
YTFLHPTVVPRPHVQSVLLTPQDEFFILGSKGLWDSLSVEEAVEAVRNVPDALAAAKKLC
TLAQSYGCHDSISAVVVQLSVTEDSFCCCELSAGGAVPPPSPGIFPSSVNMVIKDRPSDG
LGVPSSSSGMASEISSELSTSEMSSEVGSTASDEPP-TGALSE--NSPAYPSEQRCMLHP
VCLSNSFQRQLSS----ATFSSAFSDNGLDSDDEEPIEGVFTNGSRVE------VEVDIH
CSRAKEKEK-Q-HLLQVPAEASDEGIVISANEDEPGLPRK-ADFSAVGTIGRRRANGSVA
PQERSHNVIEVATDAPLRKPGGYFAAPAQPDPDDQFIIPPELEEEVKEIMKHHQEQQ---
--QQPPP---PP---P---------PL--QPQLPRHYQLEQLPDYYDTPL

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------------------------------------------------------------
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-------------MDSEIGCLIRFY--AGKPHSTGSSERIQLSGMYNVRKGKMQLPVNRW
TRRQVILCGTCLIVSSVKDSLTGKMHVLPLIGGKVEEVKKH-QHCLAFSSSGPQSQTYYI
CFDTFTEYLRWLRQVSKVASQRISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLRQNP
SLPAARGLHELQRF-T

PF00560 // ENSGT00440000037833_1_Domain_3 (797, 814)

KLKSLNLSNNHLGDFPLAVCSIPTLAELNVSCNALRSVPAAIGV
MHNLQTFLLDGNFLQSLPAELENMKQLSYLGLSFNEFTDIPEVLEKLTAVDKLCMSGNCM
ETLRLQALRKMPHIKHVDLRLNIIRKLIA-DEVDFLQHVTQLDLRDNKLGDLDAMIFNNI
EVLH----------------------C----------------ERNQLVTLDICGYF---
LKALYASSNELVQLDVYPVPNYLSYMDVSRNRLENVPEWVCESR

PF00560 // ENSGT00440000037833_1_Domain_10 (1065, 1086)

KLEVLDIGHNQICELP
ARLFCNSSLRKLLAGHNQLARLPERLERTSVEVLDVQHNQLLELPPNLLMKADSLRFLNA
SANKLESLPPATLSEETNS---ILQELYLTNNSL----------------------TDKC
VPLLTGHPHLKILHMAYNRLQSFPA-SKMAK-----------------------------
-----LEE

PF00560 // ENSGT00440000037833_1_Domain_16 (1269, 1288)

LEEIDLSGNKLKAIPTTIMNCRRVHTVIAHSNCIEVFPEVMQLPEIKCVDLS
CNELSEVTLPENLPPKLQELDLTGNPRLVLDHKTLELLN-NIRCFKIDQPSTG----DAS
GAPAVWSH

PF00481 // ENSGT00440000037833_1_Domain_18 (1389, 1632)

GYTEASGVKNKLCVAALSVNNFCDNREALYGVFDGDRNVEVPYLLQCTMSDI
LAEELQKTKNEEEYMVNTFIVMQRKLGTAGQKLGGAAVLCHIKHDPVDPGGSFTLTSANV
GKCQTVLCRNGKPLPLSRSYIMSCEEELKRIKQHKAIITED-GKVN--GVTES-TRILG-
YTFLHPSVVPRPHVQSVLLTPQDEFFILGSKGLWDSLSVEEAVEAVRNVPDALAAAKKLC
TLAQSYGCHDSISAVVVQLSVTEDSFCCCELSAGGAVPPPSPGIFPPSVNMVIKDRPSDG
LGVPSSSSGMASEISSELSTSEMSSEVGSTASDEPP-PGALSE--NSPAYPSEQRCMLHP
VCLSNSFQRQLSS----ATFSSAFSDNGLDSDDEEPIEGVFTNGSRVE------VEVDIH
CSRAKEKEKQQ-HLLQVPAEASDEGIVISANEDEPGLPRK-ADFSAVGTIGRRRANGSVA
PQERSHNVIEVATDAPLRKPGGYFAAPAQPDPDDQFIIPPELEEEVKEIMKHHQEQQ---
QQQQ-PP---PP---P---------QL--QPQLPRHYQLDQLPDYYDTPL

------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------MDSEIGCLIRFY--AGKPHSTGSSERIQLSGMYNVRKGKM

PF00169 // ENSGT00440000037833_1_Domain_0 (654, 738)

QLPVNRW
TRRHVILCGTCLIVSSVKDSLTGKMHVLPLIGGKVEEVKKH-QHCLAFSSSGPQSQTYYI
CFDTFTEYLRWLRQVSKVASQRISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLRQNP
SLPAARGLSELQRF-

PF13516 // ENSGT00440000037833_1_Domain_3 (796, 810)

TKLKSLNLSNNHLG

ENSGT00440000037833_1_Linker_3_4 (810, 819)

DFPLAVCSI

PF13855 // ENSGT00440000037833_1_Domain_4 (819, 876)

PTLTELNLSCNALRAVPAAVGA
MHNLQTFLLDGNFLQSLPAELENMHQLSYLGLSFNEFTDIPEVLEKLTAVDKLCMSGNCM
ETLRLQSLRRMPHIKHVDLRLNILRKLTA-DEVEFL

PF13516 // ENSGT00440000037833_1_Domain_8 (937, 952)

QHITQLDLRDNKLGDLDAMIFNNI
EVLH----------------------C----------------ERNQLVTLNICGYF---
LKALYASSNELVQLDVYPVPNYLSYMDVSRNHLENVPEWVCESR

PF00560 // ENSGT00440000037833_1_Domain_10 (1065, 1086)

KLEVLDIGHNQICDLP
ARLFCNSSLRKLLAGHNQLARLPERLERTSVEVLDVQHNQLIELPPNLLLKADSLRFLNA
SANKLETIPPATLSEETNS---I

PF13855 // ENSGT00440000037833_1_Domain_15 (1164, 1279)

LQELYLTNNNL----------------------TDKC
VPLLTGHPRLKILHMAYNRLQSFPA-SKMAK-----------------------------
-----LEELEEIDISGNKLKAIPTTIMNCRRMHTVIAHSNCIEVFPEVMQLPEIKCVDLS
CNELSEVTLPENLPPKLQELDLTGNPRLALDHKTLELLN-NIRCFKIDQPSAG----DAS
GAPAVWSH

PF00481 // ENSGT00440000037833_1_Domain_18 (1389, 1632)

GYTEASGVKNKLCVAALSVNNFCDNREALYGVFDGDRNVEVPYLLQCTMSDI
LAEELQKTKNEEEYMVNTFIVMQRKLGTAGQKLGGAAVLCHIKHDPVDPGGSFTLTSANV
GKCQTVLCRNGKPLPLSRSYVMSCEEELKRIKQHKAIITED-GKVN--GVTES-TRILG-
YTFLHPSVVPRPHVQSVLLTPQDEFFILGSKGLWDSLSIEEAVEAVRNVPDALAAAKKLC
TLAQSYGCHDSISAVVVQLSVTEDSFCCCELSTGGSVPPPSPGIFPPSVNMVIKDRPSDG
LGVPSSSSGMASEISSELSTSEMSSEVGSTASDEPP-PGALNE--SSSAYLSEQRCMLHP
VCLSNSFQRQLSS----ATFSSAFSDNGLDSDDEEPIEGVFTNGSRVE------VEVDIH
CIRAKEKEKQQ-HLLQLPAEASDEGIVISANEDEPGLPRK-ADFSSVGTIGRRRPNGSVA
PQERSHNVIEVAADAPLRKPGGYFAAPAQPDPDDQFIIPPELEEEVKEIMKHHQEQQQQQ
PPQ------------IQ------------QQPLQRQFQMDQLPDYYDTSL

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------MQLQPSDRDWVRHQLQRGCVHVFDRHMASTYLRPVLCTLDT
TAGEVAARLLQQGHK----GGGVVKVLGQGSRPAASRSGVEL----PPDAGPRLLPPEPR
DLEPPPPRSA---LGAVGAPPRAPPA-DLPLPDGGR-------------GGWARYTSRAS
PAPSDSSPGEPFA-----RGPASPPGTPRPLDGSAAG--PASDTESFSLSPSAE--SVSD
RLDPYSSGGGSSSS-SEELDTDP---------------APTGAPGQ-PRR----------
--------PAPASPPWPQQKAPRGVDGPS-------GVARGEPAGEKVAAAAAPGSPQ--
STPGRSGAAAEKAPPPP----PPPTLYVQLHGETTRRLEADEKPLQIQNDYLFQLGFG--
ELWRVQE----EGMDSEIGCLIRFY--AGKPHSTGSSERIQLSGMYNVRKGKM

PF00169 // ENSGT00440000037833_1_Domain_0 (654, 738)

QLPVNRW
TRRQVILCGTCLIVSSVKDSLTGKMHVLPLIGGKVEEVKKH-QHCLAFSSSGPQSQTYYI
CFDTFAEYLRWLRQVSKVASQRISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLRQNP
NLPAARGLNELQRF-

PF13516 // ENSGT00440000037833_1_Domain_3 (796, 810)

TKLKSLNLSNNHLGDFPLAVCSIPTLVELNVSCNALRAVPAAVGA
MHNLQTFLLDGNFLQSLPAELENMHQLSYLGLSFNEFTDIPEVLEKLTAMDKLCMSGNCM
ETLRLQALRRMPHIKHVDLRLNVIRKLIA-DEVDFL

PF13516 // ENSGT00440000037833_1_Domain_8 (937, 952)

QHVTQLDLRDNKLGDLDAMIFNNI
EVLH----------------------C----------------ERNQLVTLNICGYF---
LKALYASSNELVQLDVYPVPNYLSYMDVSRNRLENVPEWVCESRKLEVLDIGHNEICELP
ARLFCNSSLRKLLAGHNQLARLPERLERTSVEVLDVQHNQLLELPPNLLMKADSLRFLNA
SANKLETLPPATLCEETNS---I

PF13855 // ENSGT00440000037833_1_Domain_15 (1164, 1279)

LQELYLTNNSL----------------------TDKC
VPLLTGHPHLKILHMAYNRLQSFPA-SKMAK-----------------------------
-----LEELEEIDISGNKLKAIPTTIMNCRRMHTVIAHSNCIEVFPEVMQLPEIKCVDLS
CNELSEVTLPENLPPKLQELDLTGNPRLVLDHKTLELLN-NIRCFKIDQPSAG----DTS
GAPAVWSH

PF00481 // ENSGT00440000037833_1_Domain_18 (1389, 1632)

GYTEASGVKNKLCVAALSVNNFCDNREALYGVFDGDRNVEVPYLLQCTMSDI
LAEELQKTKNEEEYMVNTFIVMQRKLGTAGQKLGGAAVLCHIKHDPVDPGGSFTLTSANV
GKCQTVLCRNGKPLPLSRSYVMSCEEELKRIKQHKAIITED-GKVN--GVTES-TRILG-
YTFLHPSVVPRPHVQSVLLTPQDEFFILGSKGLWDSLSVEEAVEAVRNVPDALAAAKKLC
TLAQSYGCHDSISAVVVQLSVTEDSFCCCELSAGGSVPPPSPGIFPPSVNMVIKDRPSDG
LGVPSSSSGMASEISSELSTSEMSSEVGSTASDEPP-SGALNE--SSPACPSEQRCMLHP
VCLSNSFQRQLSS----ATFSSAFSDNGLDSDDEEPIEGVFINGSRVE------VEVDIH
CSRAKEKEKQQ-HLLQVPAEASDEGIVISANEDELGLPRK-ADFSAVGTIGRRRANGSVA
PQERSHNVIEVATDAPLRKPGGYFAAPAQPDPDDQFIIPPELEEEVKEIMKHHQEQQQQQ
QQQPQPH---PQ---P--------QLQ--QPPPQRHYQVDQLPDYYDTPL

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---------------------------SGKPHSTGSSERIQLSGMYNVRKGKIHLPVNRW
TRRQAILCGTCLIVSSVKESQTGKMHVLPLIGGKVEEVKKH-QHCLAFSSSGPQSQTYYI
CFDNFTEYLRWLRQASKVASQRISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLRLNP
SPSTSRALSELQRF-T

PF00560 // ENSGT00440000037833_1_Domain_3 (797, 814)

KLKSLNLSNNNLGDFPLAVCSIPTLTELNLSCNALRSIPAVVGE
MHNLQTFLLDGNFLQSLPDELEHIHQLSYVSLSFNEFTDIPGVLEKLTAMDKLCMSGNCI
DTLNLQVLKRMPHIKHVDLRLNSIRRLES-DEIDFLHHVTQLDLRDNKLGELDATVFNNV
EVLH----------------------C----------------ERNQLVTLKISGYF---
LKALYASCNELVHLDVYPVPNCLAYMDISRNHLENLPEWVCDSR

PF00560 // ENSGT00440000037833_1_Domain_10 (1065, 1085)

KLEVLDVGHNQIRELP
ARLFYNSSLRKLLAGHNMLGRLPDRLERTQVEVLDVQHNQLLELPSNLLLKADSLRFLNA
SANKLEMLPPATLSEETHS---ILQELYLTNNNL----------------------TDKC
VPLLTGHPHLKILHMAYNRLQSFPA-SKMAK-----------------------------
-----LEELEEIDISGNKLKAIPTTIMNCRRMHTVIAHSNCIEVFPEVMQLSEIKCVDLS
CNELSEVTLPENLPPKLQELDLTGNPRLALDHKTLELLN-NIRCFKIDQPSAG----DAS
GAPAVWSHG

PF00481 // ENSGT00440000037833_1_Domain_18 (1390, 1632)

YTEASGVKNKLCVAALSANNFCDNREALYGVFDGDRNVEVPYLLQCTMSDI
LAEELQKTKNEEEYMINTFIVMQRKLGTAGQKLGGSAVLCHIKHDPMDPGGCFTLTSANV
GKCQTVLCRNGKPLPLSRCYVMSCEEELKRIKQHKAIITED-GKVN--GVTDS-TRILG-
YTFLHPSVVPRPHVQSITLTPQDEFFILGSKGLWDSLSMDEAVEAVRNVPDALAAAKKLC
TLAQSYGCNDSISAVVVQLNVTEDSFCCCELN---GVPPPSPGIFPQSVNVVIKDRPADA
LGMPSSSSGMASEISSEISTSEMSSEVGSTASDEPP-QVTMNE--NSPAYPGEQRCMLHP
VCLSNSFQRQLSS----ATFSSAFSDNGLDSDDEEPIEGVFTNGSRVE------VEVDIH
CSRAKEKQ---L--LQVPVEASDEGIVISANEDEPGLPRK-AEYSATGTIGRRRGNGSVA
PHERSHNLIEVATDAPLRKTGGYFAAPAQPDPDDQFIIPPELEEEVKEIMKQHQEQQQQQ
Q-Q--------------------------QQQQQKQYPMDHLADYYDTPL

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---------------------------------------------------------MEP
AAAATAQRSA---PGAVGGPPRAPPA-DLPLPAGVP-------------GGWSR---RAS
PAPSDSSPGEAFV-----GGPASSPCALRPVA---------SDTESFSLSPSAE--SVSD
RLDPYSSGGG-SS-SSEEVEADA-------------ASAPTGVPGQ-PR--------RPG
RSAQPLPPSQTASSPQPQQKAPRAVDSPG-------GAVREGPCEEKAAAFVAPGGLQST
--PGRSGVTAEKA---P----PPPTLYVQLHGETTRRLEAEEKPLQIQNDYLFQLGFG--
ELWRVQE----EGMDSEIGCLIRFY--AGKPHSTGSSERIQLSGMYNVRKGKM

PF00169 // ENSGT00440000037833_1_Domain_0 (654, 738)

QLPVNRW
TRRQVILCGTCLIVSSVKDSLTGKMHVLPLIGGKVEEVKKH-QHCLAFSSSGPQSQTYYI
CFDTFTEYLRWLRQVSKVASQRISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLRQNP
SLPAARGLNELQRF-

PF13516 // ENSGT00440000037833_1_Domain_3 (796, 810)

TKLKSLNLSNNHLG

ENSGT00440000037833_1_Linker_3_4 (810, 819)

DFPLAVCSI

PF13855 // ENSGT00440000037833_1_Domain_4 (819, 876)

PTLAELNVSCNALRSVPAAVGV
MHNLQTFLLDGNFLQSLPAELENMKQLSYLGLSFNEFTDIPEVLEKLTAVDKLCMSGNCM
ETLRLQALRKMPHIKHVDLRLNIIRKLIA-DEVDFL

PF13516 // ENSGT00440000037833_1_Domain_8 (937, 952)

QHVTQLDLRDNKLGDLDAMIFNNI
EVLH----------------------C----------------ERNQLVTLDICGYF---
LKALYASSNELVQLDVYPVPNYLSYMDVSRNRLENVPEWVCESRKLEVLDIGHNQICELP
ARLFCNSSLRKLLAGHNQLARLPERLERTSVEVLDVQHNQLLELPPNLLMKSDSLRFLNA
SANKLESLPPATLSEETNS---I

PF13855 // ENSGT00440000037833_1_Domain_15 (1164, 1279)

LQELYLTNNSL----------------------TDKC
VPLLTGHPHLKILHMAYNRLQSFPA-SKMAK-----------------------------
-----LEELEEIDLSGNKLKAIPTTIMNCRRVHTVIAHSNCIEVFPEVMQLPEIKCVDLS
CNELSEVTLPENLPPKLQELDLTGNPRLVLDHKTLELLN-NIRCFKIDQPSTG----DAS
GAPAVWSH

PF00481 // ENSGT00440000037833_1_Domain_18 (1389, 1632)

GYTEASGVKNKLCVAALSVNNFCDNREALYGVFDGDRNVEVPYLLQCTMSDI
LAEELQKTKNEEEYMVNTFIVMQRKLGTAGQKLGGAAVLCHIKHDPVDPGGSFTLTSANV
GKCQTVLCRNGKPLPLSRSYIMSCEEELKRIKQHKAIITED-GKVN--GVTES-TRILG-
YTFLHPSVMPRPHVQSVLLTPQDEFFILGSKGLWDSLSVEEAVEAVRNVPDALAAAKKLC
TLAQSYGCHDSISAVVVQLSVTEDSFCCCELSAGGAVPPPSPGIFPPSVNVVIKDRPSDG
LGVPSSSSGMASEISSELSTSEMSSEVGSTASDEPP-PGALSE--NSPAYPSEQRCMLHP
VCLSNSFQRQLSS----ATFSSAFSDNGLDSDDEEPIEGVFTNGSRVE------VEVDIH
CSRAKEKEKQQ-HLLQVPAEASDEGIVISANEDEPGLPRK-ADFSAVGTIGRRRANGSVA
PQERSHNVIEVATDAPLRKPGGYFAAPAQPDPDDQFIIPPELEEEVKEIMKHHQEQQ---
QQQQ-PP---PP---P---------QL--QPQLPRHYQLDQLPDYYDTPL

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---------------------SRSRG--------------------------CPGGWITR
SGPGQYGET-------------------------LSL-------LKIQKLARHGVLIS--
GMQMSRK----SFHFKRITCLLVFI--SGKPHSMGSSERIQLSGMYNVRKGKM

PF00169 // ENSGT00440000037833_1_Domain_0 (654, 738)

QLPVNRW
TRRQVILCGTCLIVSSVKDSLTGKMHVLPLIGGKVEEVKKH-QHCLAFSSSGPQSQTYYI
CFDTFTEYLRWLRQVSKVASQRISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLRQNP
SLPAARGLNELQRF-

PF13516 // ENSGT00440000037833_1_Domain_3 (796, 810)

TKLKSLNLSNNHLG

ENSGT00440000037833_1_Linker_3_4 (810, 819)

DFPLAVCSI

PF13855 // ENSGT00440000037833_1_Domain_4 (819, 876)

PTLAELNVSCNALRSVPAAVGV
MHNLQTFLLDGNFLQTLPAELENMKQLSYLGLSFNEFTDIPEVLEKLTAVDKLCMSGNCM
ETLRLQALRKMPHIKHVDLRLNIIRKLIA-DEVDFL

PF13516 // ENSGT00440000037833_1_Domain_8 (937, 952)

QHVTQLDLRDNKLGDLDAMIFNNI
EVLH----------------------C----------------ERNQLVTLDICGYF---
LKALYASSNELVQLDVYPVPNYLSYMDVSRNRLENVPEWVCESR

PF00560 // ENSGT00440000037833_1_Domain_10 (1065, 1086)

KLEVLDIGHNQICELP
ARLFCNSSLRKLLAGHNQLARLPERLERTSVEVLDVQHNQLLELPPNLLMKADSLRFLNA
SANKLESLPPATLSEETNS---I

PF13855 // ENSGT00440000037833_1_Domain_15 (1164, 1279)

LQELYLTNNSL----------------------TDKC
VPLLTGHPHLKILHMAYNRLQSFPA-SKMAK-----------------------------
-----LEELEEIDLSGNKLKAIPTTIMNCRRVHTVIAHSNCIEVFPEVMQLPEIKCVDLS
CNELSEVTLPENLPPKLQELDLTGNPRLVLDHKTLELLN-NIRCFKIDQPSTG----DAS
GAPAVWSH

PF00481 // ENSGT00440000037833_1_Domain_18 (1389, 1632)

GYTEASGVKNKLCVAALSVNNFCDNREALYGVFDGDRNVEVPYLLQCTMSDI
LAEELQKTKNEEEYMVNTFIVMQRKLGTAGQKLGGAAVLCHIKHDPVDPGGSFTLTSANV
GKCQTVLCRNGKPLPLSRSYIMSCEEELKRIKQHKAIITED-GKVN--GVTES-TRILG-
YTFLHPSVVPRPHVQSVLLTPQDEFFILGSKGLWDSLSLEEAVEAVRNVPDALAAAKKLC
TLAQSYGCHDSISAVVVQLSVTEDSFCCCELSAGGAVPPPSPGIFPPSVNMVIKDRPSDG
LGVPSSSSGMASEISSELSTSEMSSEVGSTASDEPP-PGALSE--NSPAYPSEQRCMLHP
VCLSNSFQRQLSS----ATFSSAFSDNGLDSDDEEPIEGVFTNGSRVE------VEVDIH
CSRAKEKEKQQ-HLLQVPAEASDEGIVISANEDEPGLPRK-ADFSAVGTIGRRRANGSVA
PQERSHNMIEVATDAPLRKPGGYFAAPAQPDPDDQFIIPPELEEEVKEIMKHHQEQQ---
QQQQ-PP---PP---P---------QL--QPQLPRHYQLDQLPDYYDTPL

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-------------------------------------------------AVTAPGRPQLT
PVWNG---TTA------EKAPLLPILNVQLHGETTRRLEADEKPLQIQNDYLFQLGFG--
ELWRVQE----EGMDSEIGCLIRFY--A-KPHSTGSSERIQL-SMY

PF00169 // ENSGT00440000037833_1_Domain_0 (647, 740)

NVRKGKMQLPVNRW
TRRQVILCGTCLIVSSVKDSLTGKMHVLPLIGGKVEEVKKH-QHCLAFSSSGPQSQTYYI
CFDTFTEYLRWLRQVSKVA

ENSGT00440000037833_1_Linker_0_1 (740, 742)

SQ

PF00560 // ENSGT00440000037833_1_Domain_1 (742, 760)

RISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLRQNP
SLPTARGLSELQRF-T

PF00560 // ENSGT00440000037833_1_Domain_3 (797, 818)

KLKSLNLSNNNLGDFPLAVCN

ENSGT00440000037833_1_Linker_3_5 (818, 820)

IP

PF00560 // ENSGT00440000037833_1_Domain_5 (820, 841)

TLTELNVSCNALRAVPAAVGV

ENSGT00440000037833_1_Linker_5_4 (841, 843)

MH

PF00560 // ENSGT00440000037833_1_Domain_4 (843, 864)

NLQTFLLDGNFLQTLPAELEN

ENSGT00440000037833_1_Linker_4_6 (864, 866)

MH

PF00560 // ENSGT00440000037833_1_Domain_6 (866, 887)

QLSYLGLSFNEFTDIPEVLEKLTAVDKLCMSGNCM
ETLRLQALQKMPHIKHVDLRLNIIRRLIA-DEVDFLQHVTQLDLRDNKLGDLDAMIFNNI
EVLH----------------------C----------------ERNQLVTLNICGYF---
LKALYASSNELVQLDVYPVPN

PF00560 // ENSGT00440000037833_1_Domain_9 (1042, 1063)

NLSYMDVSRNHLENVPEWICE

ENSGT00440000037833_1_Linker_9_10 (1063, 1065)

SR

PF00560 // ENSGT00440000037833_1_Domain_10 (1065, 1087)

KLEVLDIGHNQIYELP
ARLFCN

ENSGT00440000037833_1_Linker_10_11 (1087, 1088)

S

PF00560 // ENSGT00440000037833_1_Domain_11 (1088, 1106)

SLRKLLAGHNRLTRLPER

ENSGT00440000037833_1_Linker_11_12 (1106, 1110)

LERT

PF00560 // ENSGT00440000037833_1_Domain_12 (1110, 1128)

SVEVLDVQHNQLLELPPN

ENSGT00440000037833_1_Linker_12_13 (1128, 1134)

LLMKAD

PF00560 // ENSGT00440000037833_1_Domain_13 (1134, 1156)

SLRFLNA
SANKLETLPPGTLSEETSS---VLQELYLTNNSL----------------------TDKC
VPLLTGHR

PF00560 // ENSGT00440000037833_1_Domain_15 (1209, 1266)

HLKILHMAYNRLQSFPA-SKMAK-----------------------------
-----

ENSGT00440000037833_1_Linker_15_16 (1266, 1268)

LE

PF00560 // ENSGT00440000037833_1_Domain_16 (1268, 1289)

ELEEIDISGNKLKALPTTVLS

ENSGT00440000037833_1_Linker_16_17 (1289, 1336)

CRRVHTVIAHSNRIEVFPEVMQLPEIKCVDLS
CNELSEVTLPENLPP

PF00560 // ENSGT00440000037833_1_Domain_17 (1336, 1358)

KLQELDLTGNPRLALDHKTLEL

ENSGT00440000037833_1_Linker_17_18 (1358, 1386)

LN-NIRCFKIDQPSAG----DAS
GAPAV

PF00481 // ENSGT00440000037833_1_Domain_18 (1386, 1632)

WSHGYTEASGVKNKLCVAALSVNNFCDNREALYGVFDGDRNVEVPYLLQCTMSDI
LAEELQKTKNEEEYMVNTFIVMQRKLGTAGQKLGGAAVLCHIKHDPVDPGGSFTLTSANV
GKCQTVLCRNGKPLPLSRSYVMSCEEELKRIKRHKAMITED-GKVN--GVTES-TRVLG-
YTFLHPSVVPRPHVQSVPLTPQDEFFILGSKGLWDSLSVEEAVGAVRNVPDALAAAKKLC
TLAQSYGCRDSLSAVVVQLSVTEDSFCCCELGAGGAVPPPSPGIFPPSVSMAIKDRPSDG
LGVPSSSSGMASEISSELSTSEMSSEVGSTASDEPP-SGALNE--NSPAYPSELRCMLHP
LCLSNSFQRQLSS----ATFSSAFSDNGLDSDDEEPIEGVFTNGSRVE------VEVDIH
CSRAKEQEKQQ-HLLQVPAEASDEGIVISANEEEPGLPRK-ADFATVGTIGRRRANGSVA
PQERSHNVIEVATDAPLRKPGGYFAAPAQPDPDDQFIIPPELEEEVKEIMKHHQQQQ---
----PPPYQ------------------PQLPQPQGXXL------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------LII
--LSRLGHA-CD-------PPASASLSSGITGLCQHT----------WQVLCFEQSPG--
LYLDVEGKI---AHFNRITCLLVFV--LGKIHSSGSSERIQLSGMYNVRKGKM

PF00169 // ENSGT00440000037833_1_Domain_0 (654, 738)

QLPVNRW
TRRHVILCGTCLIVSSVKDSLTGKMHVLPLIGGKVEEVKKH-QHCLAFSSSGPQSQTYYI
CFDTFTEYLRWLRQVSKVASQRISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLRQNP
SLPAARGLNELQRF-

PF13516 // ENSGT00440000037833_1_Domain_3 (796, 810)

TKLKSLNLSNNHLG

ENSGT00440000037833_1_Linker_3_4 (810, 819)

DFPLAVCKI

PF13855 // ENSGT00440000037833_1_Domain_4 (819, 876)

PTLTELNVSCNALRTVPAAVGA
MHNLQTFLLDGNFLQYLPAELENMHQLSYLGLSFNEFTDVPEVLEKLTAVDKLCMSGNCM
ETLKLQALRRMPHIKHVDLRLNIIRKLIA-DEVDFL

PF13516 // ENSGT00440000037833_1_Domain_8 (937, 952)

QHVTQLDLRDNKLGDLDAMIFNNI
EVLH----------------------C----------------ERNQLVTLSICGYF---
LKALYASSNELVQLDVYPVPNYLSYMDVSRNHLENVPEWVCESR

PF00560 // ENSGT00440000037833_1_Domain_10 (1065, 1086)

KLEVLDIGHNQICDLP
ARLFCNSSLRKLLAGHNQLARLPERLERTSVEVLDVQHNQLVELPPNLLLKADCLRFLNA
SANKLETLPPATLSEETNS---I

PF13855 // ENSGT00440000037833_1_Domain_15 (1164, 1279)

LQELYLTNNNL----------------------TDKC
VPLLTGLPHLKILHMAYNRLQSFPA-SKMAK-----------------------------
-----LEELEEIDISGNKLKAIPTTITSCRRMHTVIAHSNCIEVFPEVMQLPEVKCVDLS
CNELSEVSLPENLPPKLQELDLTGNPRLVLDHKTLELLN-NIRCFKIDQPSAG----DAS
GAPAVWSH

PF00481 // ENSGT00440000037833_1_Domain_18 (1389, 1632)

GYTEASGVKNKLCVAALSVNNFCDNREALYGVFDGDRNVEVPYLLQCTMSDI
LAEELQKTKNEEEYMVNTFIVMQRKLGTAGQKLGGAAVLCHIKHDPMDPGGSFTLTSANV
GKCQTVLCRNGKPLPLSRSYVMSCEEELRRIKQHKAIITED-GKVN--GVTES-TRILG-
YTFLHPSVVPRPHVQSVLLTPQDEFFILGNKGLWDSLSIEEAVEAVRNVPDALAAAKKLC
TLAQSYGCHDSISAVVVQLSVTEDSFCCCELSTGGSVPPPSPGIFPPSVNMVIKDRPSDG
LGVPSSSSGMASEISSELSTSEMSSEVGSTASDEPP-SGALNE--SNSAYPSEQRCMLHP
VCLSNSFQRQLSS----ATFSSAFSDNGLDSDDEEPIEGVFTNGSRVE------VEVDIH
CSRAKEKEKQQ-HLLQVPAEASDEGIVISANEDEPGLPRK-ADFSSVGTIGRRRANGSVA
PQERSHNVIEVAADAPLRKPGGYFAAPAQPDPDDQFIIPPELEEEVKEIMKHHQEQQ-QQ
PPP------------LQ------------QQPLQRQFQMDQLPDCYDTPL