ENSGT00440000034554_2 : Linker Region Query Results

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-----------------------------------------MED--SMDM-DMSPL----
--RPQ-NY---LFDCEL--KADK-DYHFKVNDDEN----EHQLS----------L-----
--RMV--SLGTKAINYEGS-PIKVA-LATLKMSVQPTVS-LGGFEITPP-V--VLRV-TF
GSGPVPIG-RQHL V--------D-VEEDAESEDEDEE---------------DRSAPGGG
-SKVPQKKVKIDEYEDDE------------------------------------------
------------------------------------GDEEDDDDCDDEEAEEK-VPVK--
-KS---------------------------------------------------------
------------------AKVQANIE-KG-------GSLPKVEAK--------FVN----
------YV--KNCFR---------------M---TDQ---MAIQDL--WQWRKSL-----
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-----------------------------------------MED--SMDM-DMSPL----
--RPQN-Y---LFGCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VYSL-LY
INALFVVP-TKFIL--------A-VEEDAESEDD-EEEDVKLL-SMS----GKRSAPGGG
-SKVPQKKVKLAADEDDEDDDDE-------------------------------------
---------------------------------DDDDEDDDDDDFDDEEAEEK-APVK--
-KSIRDTPA-KNAQKSN-----QNGKDSKPS-TP-----------RSKGQESFKK--QEK
---TPKTPKGPSSVEDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDV---EAIQDL--WQWRKSL-----
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-------------------

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-----------------------------------------MED--SMDM-DMSPL----
--RPQ-NY---LFGCEL--KAEK-DYHFKVDNDEN----EHELSLRM---VS-LGLGAAA
KDELH--IAEAEAMNYEGS-PIKVT-LATLKISVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVCIS-GQHL V--------A-VEEDAESDEE-EEEDVKLL-SIS----GKRSAPGSG
-SKVPQKKTDEDDDDDDD--N---------------------------------------
-----------------------------------DDEDDDHNDFDEE--VEEKAPVK--
-KWIRDTPA-KNAQKSN-----QNGKDSK-PSTP-----------RSKGQESFKN-----
------------SV EDIKAKMHTSIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------I---SDQ---EAIQDL--WQWRKSLFFFSF
FWYQGLNSGPYACAAGS--KTTELNPRPLKEVSLRKQFKQFVKIFLLISFL---------
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-------------------

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-----------------------------------------MED--SMDM-DMSLL----
--RPW-DY---LFSCEL--KTNK-DDHFKVDNDEN----EHQL--------S-LGA--GA
KDEF----------------LIKVT-LAALKMSVQPAVS-LGGFEIPPP-V--VLRL-KC
GSGPVHIS-GQHL V--------A-VEEDEESEDE-EEEDVKLL-SIS----GKRSAPGGG
-SKVPQKKVKLA------------------------------------------------
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---SNRNGI-DS---------------KPS-STP-----------RSKGQESFKK--QEK
---NPKTPKGPSSV EDIKAKMQASIE-KG-------GSLPRVEAK--------FIN----
------YV--KNCFR---------------T---TEQ-----------------------
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-------------------

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-----------------------------------------MED--SMDM-DMSPL----
--RVPLGF---LISISL--I----IITLRWINDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHL V--------A-VEEDAESEDE-EEEDVKLL-SMS----GKRSAPGGG
-SKVPQKKVKLAADEDDDDED-D-------------------------------------
---------------------------------DDDDEDDDDDDFDDEETEEK-VPVK--
-KSIRDTPA-KNAQKSN-----QNGKDSKPSSTP-----------RSKGQESFKK--QEK
---TPKTPKGPSSV EDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRNLN-----
---------------------------------------NLLKIFRLISFL---------
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-------------------

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-----------------------------------------MED--SMDM-DMSPL----
--RPQ-NY---LFGCEL--KSDK-DDHFKVDNDEN----EHQLSLRT---VS-VGA--GA
KDELH--ILEAEAMNYKG--------SPIKKMSVQPTGS-LGGFEITPP-V--VLRL-KH
ISGQ-------H LV--------A-V-----------EEDVKLL-SMS----GKWSAPGGG
-SKVPHKKVKLAADEDDDDD----------------------------------------
--------------------------------------------FDDEETEEK-VP----
------------------------------------------------DKNPSKN--RKK
---TPKTPKGPSSV EDIKAKMQASIE-NG-------GSLPKVEAK--------FIN----
------YV--KNCFW---------------M---TDQ---EAIQDL--WQWRKSL-----
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-------------------

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-----------------------------------------MED--SVDM-DMSPL----
--SSQ-KY---LFGCKL--KADK-D-HFKVDNDEN----EHQLSFRK---DS-LGA--GA
KGESH--VAEAEAMDMKAV-QLKVT-LATLQMFVQPKAS-LGGLEITLA-I--VLQL-KC
GLGPMHIS-H--LA--------A-VEE-----SD-EEEDAKSL-SLS----GKQSAPGSS
-SKFPHKKKLATDEDEYD------------------------------------------
-------------------------------------EGDDEDGEHNEETEEK-APVE--
-KSIRGTPA-KNTQKSN-----EMNDSLS-S-TP-----------RSEVK---NPFKN--
RKKPPTTLKGPSSIEDIKQGRTVTLM-KK-------H-----------------------
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-----------------------------------------MED--SMDM-DMSPL----
--RPQN-Y---LFGCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHLV--------A-VEEDAESEDE-EEEDVKLL-SIS----GKRSAPGGG
-SKVPQKKVKLAADEDDDDDD---------ED----------------------------
---------------------------------D-DDEDDDDDDFDDEEAEEK-APVK--
-KSIRDTPA-KNAQKSN-----QNGKDSKPSSTP-----------RSKGQESFKK--QEK
---TPKTPKGPSSV EDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EVTEFSGDKMKSNLN-----
---------------------------------------NLLKIFRLISFL---------
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-------------------

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-----------------------------------------MED--SMDM-DMSPL----
--RPQN-Y---LFGCEL--KADK-DYHFTGHNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHLV--------A-VEEDAESEDE-EEEDVKLL-SIS----GKRSAPGSG
-SKVPQKKVKLAADEDDDDDDDD-------------------------------------
---------------------------------DDDDEDDDDDDFDDEEAEEK-APVK--
-KSVRDTPA-KNAQKSN-----QNGKDSKPTTPR----------S--KGQESFKK--QEK
---TPKTPKGPSSVEDIKAKMQASIE-KG-------GSLPKVEAK--------FVN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRKSL-----
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-----------------------------------------MED--SMDM-DVSPL----
--RPQ-NY---LFGCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQH LS-----------------EDE-KEEDVKLL-SMS----GKWSAPGGG
-SKVPQKKVKFATDEDDDDEDD---------D----------------------------
----------------------------------DEDDDDD-DDFNDEETEE-KMPVK--
-KSIRDTP--------------------AK-NSQ-----------K-----------SNQ
---NGKDSKPSTSV EDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRNL------
N--------------------------------------NLLKIFHLISFL---------
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------------------------------------------MD--SMDM-DMSPL----
--RPQN-Y---LFGCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LSA--VT
KDELH--IIEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLKL-KC
ASGPVHIS-GQHL V--------A-VEEDAESDDE-DEEDVKLL-NMS----GKRSAPGGG
-SKVPQKKVKLDEDDDEDDE----------D-----------------------------
---------------------------------DEDDEDDDDDDFDDEEAEEK-VPVK--
-KSVRDTTA-KNAQKSN-----QNGKDLKPSTP------------RSKGQKSFKK--QEK
---NPKTPKGPSSV EDIKTKMQTSIE-KG-------VSLPKVEAK--------FIN----
------YV--KNCFQ---------------M---TNQ---EAIQDL--WQAIGSK-----
---------------------------------------SL-------------------
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-----------------------------------------MED--SMDM-DMSPL----
--RPQ-NY---LFGCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVSLG-------------------
---------GFEIT------------------------PPVVL-H IS----GKRSAPGGG
-ND---------------EDDE---------D----------------------------
---------------------------------DDDDEDDDDDDFDDEETEE-KAPVK--
-KSVRDTPA-KNVQKSN-----QNGKDSKPS-TP-----------RSKGQQSIKK--QEK
---TPKTPKGPSSV EDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRKSL-----
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-----------------------------------------MED--SMDM-DMSPL----
--RPQ-NY---LFSCEL--KADK-DYHFKVDNDEN----EHQLSLRM---VS-LGA--GA
KDELY--IEEAEAMNYEG--------GL-----IKPTVS-LGGFEITPP-V--VLRL-KC
G SQ----------V--------A-VEEDAESNDE-EEEDVKLL-SIS----GKRSAPGSG
-SKVPQKKVKLVADEDDEDDDK---------D----------------------------
---------------------------------NDDDNDD----FDDEEAEEK-AT----
------------------------------------------------VKNP--S--KNK
---TPKTLKGPSSV EDIKTKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFW---------------M---TDQ---EAIQDL--WQWRKSL-----
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-----------------------------------------MED--AMDM-DMSPL----
--RPQ-NY---LFGCEL--KADK-DDHFKVDNDEN----KHQLSLKT---VS-LGA--GA
KDELQ--LVEAQAMNYEGS-PTKVT-LATLKMSLQPMVS-LVGFEI---------TP-PC
GSGPVHIS-GQHL V--------A-VEEDAR-EDE-EEGDVKLL-SIS----GNRLAPGDG
-SKFPQKKVKLAADEDDDDDFD---------T----------------------------
--------------------------------------PDKNAQNSNQNG-----KD---
---------------------------SKPLSTP-----------RSKGQESFKKQ-EKK
---TPKTPKGPSSV EDIKAKMQASTE-KG-------GSLPKVEN----------------
------------CFW---------------M---TDQE---AIQDL--WQWRNLNSLLKI
F--------------------------------------HLISFW---------------
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-----------------------------------------MED--SMDM-DMSPL----
--RPQN-Y---LFGCEL--KADK-DYHFEVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHLV--------A-VEEDAESEDE-EEEDVKLL-S-------KHSVPGSG
-SKIPQKKVKLAADEDDDDDDDD-------------------------------------
---------------------------------HDDDEDDDDDDFDDEEAEEK-APVK--
-KSIRDTPA-KNAQKSN-----LNGKDSKPSTPR----------T--KGQESFKK--QEK
---TPKTPKGSSSVEDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRKSL-----
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-----------------------------------------VED--LIDM-DMSPL----
--RQ--NY---LFTCKL--KADK-DYYFKVDNDEN----EHQLSLRT---VS-LGS--GT
KDELH--IVEAEEMNYEGS-PIKVT-LAILKMSVQPAVS-LGSFEITSP-I---LRL-QC
SSGPVHIS-GQHIV--------T-VEENAESEDE-EEDDVKNL-STS----GKRSAPGNG
-SKVPPD-----------------------------------------------------
--------------------------------------DSYDNDFDDEEMEEK-SPVK--
-KSVRESQA-KNACKSN-----QNGKDS-KPSTP-----------KSKGQDSFQK---QE
---KPKPLEGPSSIENFKAKMQASIE-KG-------DSLPKVEAK--------FIK----
------YVKN--SFQ---------------I---TDHKV-KPINQS--KQTNKPI-----
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-----------------------------------------------MDM-DMSPL----
--RPQ-DY---LFGCEL--KANK-DYHIKVDNDEN----EHQLSLRT---VS-FGA--GA
KDELH--IVEAEAMNYEG-----IT-LATLKMSVQPTVS-LGGFGIT-------------
--PP----------------------------------VVLRL-NIS----GKQSAPESG
-SKFPQKKVKLAADADD-------------------------------------------
----------------------------------DDDD--DDNDFDEEEAEEK-APVK--
-KLIRDTLA-KNAQKSN-----QNGKDSKPS-TP-----------RSKGQESFKK--QEK
---TPKTPKGP--------------K -KG-------GSLPKVEAK--------FIN----
------YV--KNCFW---------------M---TDQ---E---------WRKSL-----
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-----------------------------------------MED--WMDM-DMSPL----
--RPQ-NY---LFSCEL--KADK-DYHFKVDNDEN----GHQLSLRM---VS-LGA--GA
KDELY--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--DLRL-KC
GSGPMHIS-GQHL V--------A-VKEGAESEDE-EEEEVKLL-SIS----GKQSAPGGG
-QKK----VKLAAGAADDDED---------------------------------------
--------------------------------------N-DGDYDDEEA-EE-KAPVK--
-KSIRDTPA-KNAQKSN-----QNGKDSKPSSTP-----------RSKGQESFKK--QEK
---SPKTPKGSSSV EDIKAKMQASIE-KG-------GSLPKVETK--------FIN----
------YV--KNFFW---------------M---TDQ---EAIQDL--WQWRNL------
N--------------------------------------NLLKIFHLISFL---------
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-----------------------------------------MED--AMDM-DMSPL----
--RPR-NY---LFGCEL--KADK-DDHFKVDNDKN----KHQLSLRT---VS-LGA--GA
KDELH--IVEAQAMNYEGS-PTKLT-LATLKMSVQPMVS-PGGFEI---------TP-PC
GSGPVHIS-GQHL V--------A-VEEDAR-EDE-EEGDVKLL-SIS----GKRSAPGGG
-SKVPQKKVKLAADEDDDDDDE--------------------------------------
---------------------------------------DDDDDFDDAETKE---KV---
---------------------------LKTIINN-----------KIKRTRILQKT-GKK
---TPKTPKGP TSIEKGGSLPKVEAK-FI-------NYVEELLL----------------
----------DD------------------------------------------------
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-----------------------------------------MED--LMDV-DMSSL----
--RPQ-NY---LFGCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IAEAEAMNYEGS-PIKVI-LATLKMSVQPTVS-LGGFEITPP-V--VLML-KC
GSGPVHIS-GQHL V--------A-VEEDAESEDE-EEEDVKLL-SIS----GKRSALGGS
-SKLPQKKVKLAADEDDD------------------------------------------
-----------------------------------DDEEDD-DDFNDEEAEE-KVPDK--
-NL----S--------------------KN-RKK-----------T-----------P--
-----KTPKGPGSV EDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRKS------
L-----------------------------------------------------------
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-----------------------------------------MKD----SM-DMSPL----
--RPQ-NY---LFGFEL--KADN-VYHFKTDNDMN----EHQLSLRT---VS-LGA--GG
KGELR--IVEAEAINYEGS-PIKVT-LATLKMSVQPTVS-LGGC K---------------
----------------------------------------TLL-SMP----GKRSAPGGG
-NKVPQKKN---------------------------------------------------
--------------------------------------------DDDEEIEEK-VPVK--
-KSVRNTPD-KNAQKSN-----QNGKDLKPS-TP-----------R--------------
-------SKGPSSV EDSKAKMQASTE-KR-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------V---TDQ---EAIQDL--CQWRKSLKENDL
N--------------------------------------SLKYSVL-LNFYNR-------
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-----------------------------------------MED--AMDV-DMSPP----
--RPQ-NS---LFGCEL--KADK-DDHFKVDNDEN----EHQLCLRT---VS-LGA--GA
EDELY--VVEAEAMNYEGS-TNQVT-LATLKMSA-PTVS-LGGFEIPPP-V--VLRL-KC
GSGPVHIS-GQHLV--------A-VEEDAESEDE-EEEDVKLL-SIS----GKRSAPGSG
-SKVPQKKVKLAA-----------------------------------------------
--------------------------------------------------------K---
---SNQNGK-DS---------------KPS-STP-----------RSKGQESFKK--QE K
---IPKTPKRPSSV EDIKAKMQASIE-KG-------GFLRRVEAK--------FIN----
------YV--KNCFR---------------T---TER---EAIQDL--WQWRKS------
L-----------------------------------------------------------
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-----------------------------------------MED--SMDM-DMSPL----
--RPQ-NY---LFGCEL--KADK-DCHFKVDNDEN----EHQLSLRT---VS-LGA--RA
KDELH--IIEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFE-ITP-----------
----------PV----------------VVKL-----LG------IS----GKRSAPGGR
-NKVPQKRVKLDE-----------------------------------------------
-----------------------------------------DDDFDEEETEE-KVPVK--
-KSVRDTPA-KNAQKSN-----QNGKDLK-PSTP-----------RSKCQESFKK--QEK
---TP KTPKGPSSV EDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIEDL--WQWRKSL-----
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------------------------------------------ED--VEGL-QMRPL----
--GPQY-F---LCGCEL--KADR-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHLV--------A-VEEDAESEEE-EEEEVKLL-SIS----GKRSAPGSG
-SKVPQKKVKLAADEDEDDDDDD-------------------------------------
---------------------------------DDDDEEDDDDDDFDEEVEEK-APVK--
-KSVRDTPA-KNAQKSN-----QNGKDSKPS-TP-----------RSKGQESFKK--QEK
---TPKTPKGPSSVEDIKAKMQASIE-KP-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRKSL-----
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-----------------------------------------MED--SMDM-DMSPL----
--RPQN-Y---LFGCEL--KADK-DDHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELY--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGAFEITPP-V--VLRL-KC
GSGPVHIS-GQHL V--------A-VEEDAESEDE-EEEDVKLL-SIS----GKRSAPGGG
-SKVPQKKVKLAADEDDDD---D-------ED----------------------------
---------------------------------D-DDEDDDDDDFDDEEAEEK-APVK--
-KSIRDTPA-KNAQKSN-----QNGKDSKPSSTP-----------RSKGQESFKK--QEK
---TPKTPKGPSSV EDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFQ---------------M---TDQ---EAIQDL--WQWRNLN-----
---------------------------------------NLLKIFRLISFL---------
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-----------------------------------------IRW--TWKM-DMSPL----
--RSQ-ND---LFSCEL--KADK-HYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDKLH--IVEAEAMNYAGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHL V--------A-VEEDAESEDE-EMEDVKLL-SIS----GKQFAPGGG
-SKFPQKKVKLAADEDDDDDDE--------------------------------------
----------------------------------DDDEDDDDDDFDDAETEE-KAPVK--
-KSIRDTPA-KNAQKSN-----QNGKDSKPSSTP-----------RSKGQESFKK--QEK
---TPKTPKGPSSV EDIKAKMQASIE-KG-------GSLPKVEAK--------LSVNI--
------------------------------------T---DLGNS---------------
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-----------------------------------------MED--SVDM-DMSPV----
--RPQ-NY---RFGCEL--KADK-DYNFTVDNDEN----EYQLSLRT---VS-LGA--GA
KDELH--IVEAEVINYEGS-PIKVT-LATLKM----------------------------
---------------------------------S-EEEDVKL L-SIS----GKRSAPGSD
-SKFPQKKVKLAADEDDDDDDE--------------------------------------
---------------------------------DNDDEDDDDDDFDDEEAED-KAPVK--
-KSIQDTPA-KNAQKSR-----QNEKDSKPS-TL-----------RSKGQESFKK--QER
---TPKTPKGPSSV EDIKGKMQASLE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFQ---------------M---TDQ---EAIQDL--WQWRKSL-----
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-------------------------------------------------M-DMSLL----
--RPQ-NY---LFGCEL--KADK-DDHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-LIKVT-LATLKMSVQPTAS-LGGFEITPP-V--VLQL-KC
GSGPVHIS-R QCLV--------A-VEEDAESEDE-EEEDVRLL-SIS----GKQSASRGG
-SKFPQKKGKLAADEDD-DDED---------D----------------------------
----------------------------------DDENDDN-DDFDEEESNQ--------
------NGK-DS---------------KPS-STP-----------RSKGQESFKK--QEK
---TPKTPKEHSSV EEIKAKMQVSIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFQ---------------M---TKQ---EATQDL--WQWRKS------
F-----------------------------------------------------------
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----------------EGS-LIKVT-LATLKMSVQPMVS-LGVFEITPA-V--VLWL-QC
GSGPVDIH-EQYLV--------A-VEEDSESEEE-EEN-VKLL-SMS----RKKSAPRGG
-NKIPQKKVKLNADEDDDEEEEEEK-----------------------------------
-------------------------------------------------S-----SSE--
-EIFMRHYS-QKYSKIK-----QNGKDSKPS-TP-----------RSKDQESF------K
KYKKPKIPSKSDSIEDIKAKMQASIE-KG-------GSLSKVEAK--------FIN----
------YV--KNCFW---------------V---TDQ---EAIQEL--WGKKRNH-----
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-----------------------------------------------VDM-GMRPL----
--RPQ-NY---LFSCEL--KANK-VYHFKVDNNEN----EHQLSLTT---IS-LGA--GA
TDELD--IVEAEAMNYEGS-PIKVT-LATLKMCVQPTVS-LGGFEITPP-V--VLQL-KC
GSGPVHIS-GQYLA--------A-VEEDAESEDE-DKEVVKLL-SIS----GKQSAPGGG
-SKLPQKKVKLAADEDDGGDD---------------------------------------
--------------------------------------------FDDKETEE-K------
-HQI---LA-KNAQKSN-----QNGKDSKPPSTP-----------RSNGQESFKK--QQK
---TPETPKGPSSVEDIKAKMQASIE-KG-------GSIPTVEAK--------FIS----
------YV--KNCFQ---------------M---TDQ---KAIQDL--WQRWNSAL----
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-----------------------------------------MED--SMDM-DMSPL----
--RPQ-NY---LFSCEL--K---------VDNDEN----EHQLSLRM---VS-LGA--GA
KDELY--IEEAEAMNYEG--------GL-----IKPTVS-LGGFEITPP-V--VLRL-KC
G SQ----------V--------A-VEEDAESNDE-EEEDVKLL-SIS----GKRSAPGSG
-SKVPQKKVKLVADEDDEDDDK---------D----------------------------
---------------------------------NDDDNDD----FDDEEAEEK-AT----
------------------------------------------------TQNHQHQ--DQK
---TPKTLKGPSSV EDIKTKMQASIE-EG-------GSLPKVEAK--------FIN----
------YV--KNCFW---------------M---TDQ---EAIQDL--WQWRKSL-----
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-------------------

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-----------------------------------------MED--SMDM-DMSHF----
--RSQ-NY---LFCCEL--KAYK-NYHLKMDSDNNEH-------QLT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEIAPP-V--VLWL-RC
GTGPVHIS-GQHLV--------A-VEEDAESEEE-DEKDVKLL-SMS----GKRSAHGGG
-NKIPQEKKVKIDEDE--------------------------------------------
------------------------------------EDDNEDDDFDNEETEEK-VPVK--
-KSVRDTPA-KNAQKSN-----QNGKDL-NLSTP-----------RSKGQESFKK--QEK
---TSKTPKGPSSVEDIKAKIQASIE-KV-------H-----------------------
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-----------------------------------------MED--SMDM-VMSPL----
--RPQ-NY---LFSCEL--KADK-DYHFKVDNDEN----EHQLSLRT---IS-LGA--GA
KDELH--IVETEAMNYEGS-PIKVT-LATLKMSVKPTVS-LGGFEITPP-V--VLQL-RC
GSGPVHIS-GQHLV--------A-VEGDAESEDE-DEEDVNSL-SMP----GKRSAPGGG
-NKVPQKKVKINEDD---------------------------------------------
-------------------------------------DDDDFNDFDDEETEEK-VPVK--
-K------------------------------------------------SSFKR--QEK
---TPKTHKGPSSVEDIKAKMQASIE-TL-------NSPGHYCFK--------SRV----
----PPSES--RCRQ---------------R-----------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--KPQ-NY---LFGCEL--KADK-DYHFKVDNDEN----EHRLSLRT---VS-LGV--GA
KGELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPMVS-LGGFDITPP-V--VLRL-KC
GSGPVHFS-GQHLV--------A-VEEDAD---------------VS----GKQSAPGGG
-SKVPQKKVKLAADEDVDDDDD--------------------------------------
------------------------------------------DFDDEET-E---------
--------------EKA-----PNGKDSKPT-TP-----------RS-----------KE
---TPETPKGPSSVEDIKAKMQASIE-KA-------H-----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQN-Y---LFGCEL--KADR-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHLV--------A-VEEDAESEEE-EEEEVKLL-SIS----GKRSAPGSG
-SKVPQKKVKLAADEDEDDDDDD-------D-----------------------------
---------------------------------DDDEEDDDDDDFD-EEVEEK-APVK--
-KSVRDTPA-KNAQKSN-----QNGKDSKPSTPR----------S--KGQESFKK--QEK
---TPKTPKGPSSVEDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRKSL-----
---------------------------------------LLKIFRLIS--F--------L
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQN-Y---LFGCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHL V--------A-VEEDAESDEE-EEEDVKLL-SIS----GKRSAPGSG
-SKVPQKKAKLAAEDDDDDD--D-------------------------------------
---------------------------------DDDDEDDDDDDFDDEEAEEK-ATVK--
-KSIRDTPA-KNAQKSN-----QNGKDSKPSTPR----------S--KGQESFKK--QEK
---TPKTPKGPSSV EDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---E-------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--WMDM-DLSPL----
--RSQ-NY---LFSCEL--KAER-DYHFQVDISEN----EHQLSLRK---VS-L-A--GA
KDELH--IVEAEEMNYKGS-PIKVT-LATLGMSVQPTAS-LGDFEITPS-V--VLQ----
-------------------------EENIESEDT-EEEDVKPF-SIC----GKHSAPGSG
-NTFPQKKKLVANEDDDD------------------------------------------
-----------------------------------------------EEAEEK-APVK--
-NLYEILQP--KVHK-------KQTRVEDSS-TP-----------RSKGQESLKKKKK-K
QEKITKTMKGPSPAEDIKAKMQTSIE-KS-------ASLPKVEAK--------LIS----
------YA--KNYFQ---------------M---IDQ---EAIQDL--WQWSKCFK----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------VED--SMDM-DMRPL----
--RPQ-NY---LFGCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GT
KDEMH--IVEAEAVNYECS-PIKVT-LAALKMSVQPKIS-LRGFEITPP-V--FLRL-KC
GSGPVCIS-GQHL V--------A-VEEDAESD-E-EEEDVKLL-SIS----GKRSAPGSG
-CKVPQKKIKLAAAEDEVEDDE---------D----------------------------
----------------------------------EDDVEDD-DDFDDEETEE-KAP----
------------------------------------------------------------
------------FV EDSKAKMQASIE-KG-------DSLPKVEAK--------FIS----
------YV--NNCFQ---------------M---TDR---EAIQDL--WQWRKS------
L-----------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQN-Y---LFGCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHL V--------A-VEEDAESEDE-DEEDVKLL-SMS----GKRSAPGGG
-NKVPQKKVKLDEDDEDDDE-----------D----------------------------
---------------------------------DEDDEDDDDDDFDDEEAEEK-VPVK--
-KSVRDTPA-KNAQKSN-----QNGKDLKPSTPR----------S--KGQESFKK--QEK
---TPKTPKGPSSV EDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DISPM----
--RPQ-NY---LFSCEL--KADK-DDHFKVDNDEN----EHQLSLRM---VS-LGA--AA
KDELL--IVEAEAMNYEGS-PIKVT-LATLKMSVQPMVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHLV--------A-VEEDSESEDK-EEENVKLL-SIS----GKQSAPGGG
-SKIPQKRVKLAADEDDDDDE---------------------------------------
-------------------------------------DDDD-DDFDDEEAEE-KAPVK--
-KSIQDTP--------------------AK-NPQ--------------------------
-----------NSVEDIKAKMQASIE-KV-------H-----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--LMDM-DMSPL----
--RPQ-NY---LFNCEL--KVDK-DYHFKFDNDEN----EHQLSLST---VS-LGA--GA
KGDFH--IVKAEPMNYEGS-PIKVT-LATLKMSVQSMVS-TGGFEITPP-L--VLWL-NC
GSGPVHIS-GQHL V--------A-VEENAESEDE-EEEDVKLL-SIS----GK-------
--S---------------------------------------------------------
------------------------------------------------------------
-------KG-QES----------FKKQ-------------------------------KK
---SPKTPERPSSVEY IKAKMQASTE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFQ---------------M---TDQ---EAIQDL--WQWWKSLEENSL
N--------------------------------------NLLKIFRLISFL---------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMEM-DMSLL----
--RPQ-NY---LFGCEL--RLTK-IITLRWI-----------------------------
-------------------------------------------MMKMST-M--ILQL-KC
GLGTVHIS-GQHLV--------A-VEEDAESEGE-EEEDVKLL-SIS----GKQSAPGGG
-SEVPQKKVKLAAEEDDDDDDE--------ED----------------------------
---------------------------------EDDDEDNDDNDEDDEEAEEK-APVK--
-KSIQDTPA-KNVQKSN-----QNGKDSKPSSTP-----------RSKGQESFKK--QEK
---TPKTPKGPSSVEDIKAKMQASTE-KG-------DSLPKVAAK--------FIS----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRN------L
N--------------------------------------NLLKIFHLISFL---------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------YEGS-PIKVT-LATLKMSVQATVS-LGGFEITPL-V--VV-----
----------------------------------------KLL-SMS----GKQSGPGGG
-SKVPQKKVKLGADEDDEDDEE---------E----------------------------
-----------------------------------DDDEDDDDDFDEEEAEE-KAPVK--
-KSIRDTPA-KNAQKSN-----QNGKDSKP-STP-----------TSEGQESFKK--QEK
---TPKTPKGPSSIEDIKAKMQATIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDV---EAIQDL--------------
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-EMSPL----
--RSQN-Y---LFSCEL--KADK-DYHFKV----------YQLSLRT---VS-LGA--GA
KDELP--IVEAEAMNYEGS-PIKVT-LATLKMFVQPTVS-LGGFEITPP-V--VLWL-KC
GSGPVHIS-GQHL V--------A-VEEDAESEDE-EEEDVKLL-SIS----GKPFDPGGG
-SKVPQKKVKLAAAEDDDDDDED-------------------------------------
-----------------------------------DDDEDDDDGFDDEEAEEK-APVK--
-KSIQDTPA-KNAQKSN-----QNGKDSKPSSTL-----------RSKGHESFKK--QEK
---TPKTPKGPSSV EDIKAKMQASIE-KG-------GSLPKVEVK--------FIN----
------YV--KNCFW---------------M---TDQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------T--EDSM-DMSPP----
--RPQ-NY---LFSCEL--KADK-DYPFKVGKDEN----EHRLSLRT---VS-FGA--GV
KDELHVHIVEAETMNYEGS-PIKVP-LTTLKMSVQPAVF-LGGFQITPP-V--VLRA---
--------------------------------------YVKLL-GMS----EKKSAPGGG
-NKIPQRKVKLGEDEEDDDDDD---------D----------------------------
------------------------------------DDDDDDDDFDEEETEEE-VPVK--
-KSI--------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
MLIVNVSWYDSILSGC---SLEQRSFISVCLLSHLSVCRHLIED--SMDM-DMSPL----
--RPQ-NY---LFGCEL--KADK-DDHFKVDNDEN----EHQLSLRT---VS-LGA--GT
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSAQPTVS-LGGFEITPP-V--VLRF-KC
GSGPVHIS-GQHL V--------A-VEEDAESEDE-EEEDVKLL-SIS----GKRSAPGGG
-SKVPQKKVKLAVDEDDDDDED--------------------------------------
--------------------------------------DDD-DDFDDEEAEE-KV-----
----------------------------------------------SKGQESFKT--QEK
---TPKTPKGSSSV EDIKAKMQASIE-KG-------GSLPTVEAE--------FIN----
------FV--KNCFW---------------M---TDQ---EAIQDL--WQWRKS------
P-----------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQN-Y---LFGCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHL V--------A-VEEDAESEDE-DEEDVKLL-GMS----GKRSAPGGG
-NKVPQKKVKLDEDDEDDDE-----------D----------------------------
---------------------------------DEDDEDDDDDDFDEEETEEK-VPVK--
-KSVRDTPA-KNAQKSN-----QNGKDLKPSTPR----------S--KGQESFKK--QEK
---TPKTPKGPSSV EDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------QQDS--PGEM-DMGPV----
--SPQ-NY---LFSCEL--KADK-SYHFKVDIDEN----EHQLSLRT---VS-LGA--DA
KDELH--IVEAEAMNYEGS-PTKVT-LATLKL------------------------L-KC
VAGPAHIS-GQHLV--------A-VEEDAESEDE-EEEDVKLL-SIP----GKWSAPGGL
-SKVPQKKSKLADEVDE-------------------------------------------
-----------------------------------------DDDSDDEETEGK-SPVK--
-KSIQDTPA-KNAQKSN-----QNGKDIKPS-TP-----------RSKGQESFKKQ--EN
---PPKTPKRTYSQPKVEAKFIK-------------------------------------
-----------NCFR---------------T---TDQ---EAIQDL--WPWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQ-NY---LSSSEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAXXXXXXXX-XXXXXXXXXXXXXXXXXXX-XXXXXXXPP-V--VLRL-KC
GSGPVHIS-GQHL V--------V-VEEDAESEDE-EEEDV--L-SMS----GKRSAPGGG
-NKVPQKKVKLAADEDDDEDED---------D----------------------------
---------------------------------DEDDEDDDDDDFDDDEAEEK-APVK--
-KSIRDIPA-KNAQKSN-----QNGKDSKPS-TP-----------RSKGQEAFKK--QEK
---TPKTPKGPSSV EDIKAKMQVSIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------VED--SMDM-DMSPL----
--KLQ-SY---LFSCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--DA
KDELH--IVEAEAMNYKGS-PIKVT-LATLKMSVQPTVK PLGGR----------------
--------------------------------------DVKLL-SIS----GKRSAPGSG
-SKVPQKTVKLAPDEDDDDDDD---------D----------------------------
-------------------------------------------DEDDEEAEE-KASVK--
-TSIRNTPA-KN-----------NGKDSKPS-TP-----------RSKGEESFKK--QEK
---TPKTPKGPSSV EDSKAKMQASIE-KG-------GFLPKVEAK--------FIN----
------YV--KNCFR---------------I---TDR---GAIQDL--WQWRKCL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMGM-DMSPL----
--GPQ-NC---LFGCEL--KADK-DYHFKVDNDEN----EHQLSLRT---V---------
-NKLH--IIEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHL V--------A-VEEDAESGDE-DEEDV--------------------
----LQKKVKLDEDGEDEDG----------------------------------------
----------------------------------DDDDDDD-DDFDDKEAEE-KVPVK--
-KS---------------------------------------------------------
------------------AKMQASIE-KD-------DSLPKVEAK--------FIN----
------YV--KNCFQ---------------I---TDQ---EVIQDL--WQWRKS------
L-----------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DTSPL----
--RPQ-DY---LFGCEL--K--------------------HQLSLRT---VS-LGA--GA
KNELH--IVEAEAMNYDGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHL V--------A-VEEDSESEDE-EEEDMKFL-SIF----GKRSAPGGG
-SKVPQKKVKLAADKDDDDD----------------------------------------
-----------------------------------ED-DDD-DDFDDEEAEE-KAPVK--
-KSIRDTP--------------------AK-NAQ-----------KSKGQESFKK--QEK
---TPKTPKGPSSV EDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRNL------
N--------------------------------------NLLKIFHLILFSVTVDTWLP-
--FL--------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQN-Y---LFGCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHLV--------A-VEEDAESEDE-EEEDVKLL-SIS----GKRSAPGSG
-SKVPQKKVKLAADEDDDEDDDD-------------------------------------
---------------------------------DDDDEDDDDDDFDDEEAEEK-APVK--
-KSVRDTPA-KNAQKSN-----QNGKDSKPSTPRTKFIFFLPPPHPAQGQESFKK--QEK
---TPKTPKGPSSVEDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EIIKEN--VKTGYSR-----
---------------------------------------SLAVEEVSLRK----------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------IPQ----
--RSQ-NY---LFGCEL--K--------------------HQLSLTT---VN-LGA--DA
KDELQ--IVEAEVMNYKGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLWL-KC
GSGPVHIS-VRHLV--------A-VKENT---------------DIS----GKWSAPGGG
-SQLPQKKLKLAAAEDDDDDDD---------D----------------------------
---------------------------------D--DDDDDDDDFDDEETEEK-APVK--
-KSICDTPA-KNARKSN-----QNGKDSKPSSTP-----------RSKGQESFKK--QEK
---TRKTPKGPSSVEDIQAKMQASIE-KI-------H-----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------VED--SMDM-DLSPL----
--RPQ-NY---LFGCEL--K-------FKVDNDEN----EHQLSLRT---IS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPAVS-LGGFEITP L-----------
--------------------------------------DVKLL-SMS----GKRSAPGGG
-SRVPQKKVKLAASADDE------------------------------------------
--------------------------------------DHADDDFGDEETEE-KAPVK--
-KFICDTPA-KTAQKSN-----QNGKDPKPTSTP-----------RSKGQESFKK--QEK
---SPKTPKGPSSV EDMKAKLQASIE-KG-------GSLPRVEAK--------FIS----
------YV--KNCFR---------------M---TDQ---EAVQDF--------------
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------G--LVDM-DTSPW----
--RPQ-NY---FFNCEL--RADK-DYPSKVDNDEN----GRQLSLRT---VR-VGA--AA
KAELH--LVEAEAVSWEGG-LGKVT-LETLNMSGQPTVS-PGGFEITPP-V--LG-P-E-
-----RVS-GQHLV--------A-VGKDAEED-------GKVL-SMS----GKQSTPGGG
-SKVPQKKVKLAAA----------------------------------------------
--------------------------------------EDENDDEEDDDDEEK-APVK--
------RSG-QNAEKSN-----QNGKDSKPS-TP-----------RSKGQESFQK-----
LGKTPKTPKGPSSVEDIRQKCKSEYR-KR-------WVSSHSGAK--------FIQ----
------CV--KSCFM---------------T---N-Q---EAVQGL--WQCRKSV-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQN-Y---LFGCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHL V--------A-VEEDAESEDE-EEEDVKLL-SIS----GKRSAPGGG
-SKVPQKKVKLAADEDDDDDD---------EE----------------------------
---------------------------------D-DDEDDDDDDFDDEEAEEK-APVK--
-KSIRDTPA-KNAQKSN-----QNGKDSKPSSTP-----------RSKGQESFKK--QEK
---TPKTPKGPSSV EDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRNLN-----
---------------------------------------NLLRIFRLISFL---------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPP----
--RPQK-Y---LFSCEL--KADK-DYHFKVDNDEN----EHQL-LRT---VS-LGA--GA
-----------EAMNYEGS-PIKVT-LAILKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHL V--------V-VEEDAESEDE-EEEDVKLL-SMS----GKRSVPGGG
-NKVPQKKVKLAADEDDEEEDED-------------------------------------
------------------------------------------DDDDDDEAEEK-APVK--
-KSIRDIPA-KNAQKSN-----QNGKDSKPSTP------------RSKGQEAFKK--QEK
---TPKTPKGPSSV EDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQ-NY---LFN-----------DHFKVDNDED----EHQLSLRM---VS-LGA--GA
KDELH--TAEAEAMNYKGS-PIKVT-LATLKMSVQPMVS-LGGFEITPP-V---------
---------GQHLV--------A-VEEDARK-DE-EEEDVKLL-SIS----GKRSAPGGG
-SKFPQKKVKLAADEDDGYEDD---------D----------------------------
----------------------------------DDDEDDDDDDFDDKETKE-KAPVK--
-QSIRDTPA-KNAQKSN-----QNGKDSKPSSTP-----------RSKGQESFKK--QEK
---TPKTPKGPSSV EDIKANMQARIE-KG-------ASLPKVEAK--------FIS----
------YV--KNCFR---------------M---TDQ---EAIQDL--------------
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQ-NY---LFGCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHLV--------A-VEEDAESDEE-EEEDVKLL-SIS----GKRSAPGSG
-SKLPQTKVKLAADEEDDDDDD---------D----------------------------
----------------------------------DDDNE-DD------------------
-----DTPA-KNAQKSN-----QNGKESKPS-TP-----------RSKGQESFKK--QEK
---TPKAPKGPSSVEDIKAKMQAISF-GI-------YHN---------------------
------I------FF---------------F---VKT---ILKLGS--WNL---------
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQN-Y---LFGCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHL V--------A-VEEDAESEDE-EEEDVKLL-SMS----GKRSAPGGG
-SKLPQKKVKLAADEDDDEDDDD-------------------------------------
-----------------------------------DDEDDDDDDEDDEETEGK-VPVK--
-KSIRNTPA-KNAQKSN-----QNGKDSKPSSTP-----------RSKGQESFKN--QEK
---TPKTPKGPNSV EDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRNLN-----
---------------------------------------NLLKIFRLISFL---------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MEN--SMDM-DMSPL----
--RPQ-NY---LFGCEL--KDDK-DYHFKVDNDEN----EHQLSLRT---AS-LGA--EA
KDELH--IVEAEAMNYKGN-PIKVT-LATLKMPVQSTVS-LGGFEITPP-V--VLRL-RC
GSGSVPIS-SQH LE--------D-AESED----EDEE---------------DRSAPGGS
-SKVPHKKVKIDEDEGEDD-----------------------------------------
----------------------------------EDNDDDKEDDDFDEEAEEK-VTLK--
-KYVPDTPA-KNAQ---------NEKDLKPS-TP-----------RSKGQ--------ES
---FKKQEKTPKTY DDIKAKMLTSIE-KG-------GSLPKVVAQ--------FIN----
------YV--KNCFW---------------M---TDQ---EAIQDL--WQWRRFLF----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MEH--SMDM-DMSPL----
--RTQN-Y---LVSCEL--KADK-DDHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYAGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHL V--------A-VEEDAESEDE-EKEDVKLL-SIS----GKQFAPGGG
-SKFPQKKVKLAADEEDDDDEED-------------------------------------
-----------------------------------NDDEDDDDDFDDKEAEEK-APVK--
-KSIRDTPA-KNAQKSN-----HNGKDSKPSSAP-----------RSKGQESFKK--QEK
---TPKTPKGPSSV EDIRAKMQASIE-KG-------GSLPKVEAK--------FIN----
------EV--KNCFR---------------M---TDQ---EAIQDL--WQWRNLN-----
---------------------------------------NLLKIFRPISFL---------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------MNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHLV--------A-VEEDAESEDE-EKENVKLL-SIS----GKQFDPGGG
-EKV-----KLAAAEDDDDDED---------N----------------------------
----------------------------------DDE D-----DM--------MIL----
----------IR---------------KLK-KKH-----------QSKRQESFKK--QEK
---TPKTPKGPSSV EDIKAKMQASIE-KG-------GSLPKVEVK--------FIN----
------YV--KNCFQ---------------M---TDQ---EAIQDL--WQWRKS------
L-----------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--LMDM-DTSSL----
--RLQ-NY---LFNCELKTKAKK-DYHFKVDNDKN----EHQLLLRM---VS-LGA--GT
KDELH--VVEA-DMNYEGS-PIKLM-MATLKMS---M-V-SGGMKIKPV-E--FC-L-KC
DSRPVHIS-RGHLV--------A-VEEEAEKEDE-EEEDVKLL-SR---------G-ALC
TRSVPHKESRPAQK-------------KCSLPRN-GTT----------------------
--------------------------------HTEDDEDDDEEDDDDEEETEE-YLMK--
-KSIRETPA-KNAQKSN-----QKGKDSKPS-IP-----------KSKCQESFKQ-----
E-KAPKTLKGSSSVEDFKAKMQARRE-KG-------GSLPKVEAK--------FIN----
------YE--KNCFW---------------M---T-D---EAIQDL--WQWGNSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--LMDM-DMSPL----
--RPQ-NY---LFNCEL--KVDK-DYHFKFDNDEN----EHQLSLST---VS-LGA--GA
KGDLH--IVKAEPMNYEGS-PIKVT-LATLKMSVQSMVS-IGGFEITPS-L--VLWL-NC
GSGPVHIS-GQHLV--------A-VEENAESEDE-EEEDVKLL-SIS----GK-------
--S---------------------------------------------------------
------------------------------------------------------------
-------KG-QES----------FK KQ-------------------------------KK
---SPKTPERPSSVEY IKAKMQASTE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFQ---------------M---TDQ---EAIQYL--WQWWKSLEENSL
N--------------------------------------NLLKIFRLISFL---------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQN-Y---LFGCAL--KADK-DYHFKVDNDEN----EHQLSLRM---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHL V--------A-VEEDAESEEE-EEEDVKLL-SIS----GKRSAPGGG
-SKVPQKKVKLTADEDNEDDEDE-------------------------------------
----------------------------------EEEEEEDDDDFDDEETEEK-AP----
-----------------------NGKDSKPSTP------------RSKGQESFKK--QEK
---SPKTPKGPSSV EDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--LMDV-DMSPL----
--RPQ-NY---LFSCEL--KADK-DYHFKVDKDEN----EHQLSLRT---VS-LAA--GA
QDEMH--IVEVEAMNYEGS-PTKVT-LATLKMSVQPTVS-LGDIEITPP-V--DLRL-KC
GSGPVHIS-GQHL V--------A-VEEDVESEEE-EEEDVPQK-Q---------VKPAAD
-ED------EQDDED---------------------------------------------
-------------------------------------EDDDDDDSDDEETEEK----P--
-P------------------------------------------------ESFKT--QEK
---SPRRPKGHSFV EDIKAKMQASIE-KG-------GSRPKVEA----------KF----
----INYVK--NCFQ---------------M---THQ---EAIQDL--WQGRKSFFFLYL
F--------------------------------------IFIYYIYLLCVCVWPAQPTRG
RGWLACGAGGSNRGP---------CALPSLFQV--------------------------G
ALDH---------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMNM-DMSLL----
--RPQ-NY---LFGYEL----------------------KHQLLLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PSKVT-LATLKMSVQPMVS-LGGFEIIPP-V--VLRL-KC
GSGPVQIS-GQHL V--------A-VEEDAELEE---KRDVNLL-SIS----EKRSVTGGV
---------KLAADEDNKDDE---------------------------------------
----------------------------------EEDEDDDDDDFDDEETKKQ-VP----
-------------------------------------------------QGSFKK--QEK
---SLKTPKGPSSV EDIKAKIQGSIE-NG-------DSLPQIEAK--------FIN----
------YVK--NCFR---------------M---TDQ---EASQDP--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------EL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LAALKMSVQPTE----------------------
---------------------------DAESDDE-EEEDVKLL-SIS----GKRSAPGSG
-SKVPQKKVKLAADEDEDEEDE---------D----------------------------
---------------------------------EDDDEDDDDDDFDDEETEE-KAPVK--
-KSIRDTPA-KNAQKSN-----QNGKDSKPS-TP-----------RSKGQESFKK--QEK
---TPKTPKGPSSVEDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--LIDR-DMSPL----
--RPQ-NY---LFSCEL--KADK-DDHFKVDNDEN----EHQ----T---VS-LGA--GA
KDELQ--IIEAEAINYEGS-PKNVC-IANSFP-WSF--------EITHP-V--VLRL-MC
GSGPVHIS-GQHLV--------A-VVEDAESEDE-EEEDVKLL-SIS----GKQSATGGG
-RKIPQKKVKLAADENDDD-----------------------------------------
---------------------------------------EEDDDFDDEEPEEK-APVK--
-QSIRDTPA-KKGQKSN-----QNGKDSKPSSIP-----------RSKGQESFKK--QEK
---TPKTPKGPSSVEDIRAKMEASIE-KH-------FGKNKMRAG--------QVS----
------INKNCKCLR---------------L---ASR---EASGSL--QSWQKRE-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQN-Y---LFGCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLQL-RH
GSGPVHIS-GQHLV--------A-VEEDAESEDE-EEEDVKLL-SIS----GKRSAPGSG
-SKVPQKKVKLAADEDDDEDDDD-------------------------------------
---------------------------------DDDDEDDDDDDFDDEEAEEK-APVK--
-KSIRDTPA-KNAQKSN-----QNGKDSKPSTPR----------T--KGQESFKK--QEK
---TPKTPKGPSSVEDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------MNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHTS-GQHLV--------T-VEEDAESEDE-KEEDVKLL-SIS----GKQSDSGGG
-SKVPQKKVKLAADEDDDDDDE---------D----------------------------
-----------------------------------D------DDDNDEEAEE-KAPVK--
-KSIQDTPA-KNAQKSN-----RNGKDSKPSSTP-----------RSKGHESFKK--QEK
---TPKTPKGPSSVEDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------VEE--SMDM-DLRPL----
--RPQ-NY---LFGCEL--KADK-DDHFQVDNDEN----EHELSLRT---FS-LRA--GA
KDELH--IAKAEAMNDKGS-PIKGT-LATLKMSVQP-VS-LSGFEITPP-A--VLRW-Q-
------------------------------------GEDVKLL-RVS----GKRCPGGGS
-SKFPQKKVKLAADEDDEDNDDDEGEKEEEEG----------------------------
------------------------------------EGKEEEEDFDEEEANPH-------
----EILQP-KNAQKSN-----QNGKDSKPS-TP-----------RSKAN-----K-QEK
---TYKTPKGPSSVEDIKAKMQASIE-KG-------GSLP----K--------FIN----
------YV--KNCFR---------------M---TDV---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------CEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTXXXXXXXXXXXX-X--XX---XX
XXXXXXXX-XXXXX--------XXVEEDAESEDE-EEEDVKLL-TMS----GKRSAPGGG
-SKVPQKKVKLAADEDDDEDDE---------D----------------------------
---------------------------------DDDDEDDDDDDFDDEEAEE-KAPVK--
-KSVRDTPA-KNAQKSN-----QNGKDSKPS-TP-----------RSKGQESFKK--QEK
---TPKTPKGPSSVEDIKAKMQASIE-KG-------GSLPKVEAK--------FVN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--LMDM-DMSPL----
--RPQ-NY---LFGCEL--KADK-DYHFKVDNDEN----EHQLCLRT---VS-LGA--GA
KDEFH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHL V--------A-VEEDAESEDE-EEEDVKLS-SMS----GKRSAPGGG
-SKVPQKKVKLAADEDDD------------------------------------------
-----------------------------------DEDDDD-DDFDDEETEV-KAPVK--
-KSICDTP--------------------AK-NEK-----------T-----------P--
-----KTPKGPSSV EDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDP---EAIQDL--WQWRNL------
N--------------------------------------SLLKIFLLISFL---------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------M-EMRPL----
--RPQ-NY---LFSCEL--KANK-DYHFKVDNIEN----EHQLSLRA---IN-LGA--GA
MDELD--TVEAEAMNYEGS-PITVT-LATLKMSVQSTVS-LGGFEITPP-V--VLQL-KC
GSGPVHIS-GHHL V--------A-VEENAESEDK-EKEDVKLL-SIS----GKQSAPGGG
-SKLPQKKVKLVADED--------------------------------------------
---------------------------------------DDGDDFYDEETEEK-APS---
----------------N-----QNGKDSKPPSTP-----------RSNGQESFKK--QQK
---SPETPKGPSSV EDIKAKMQASIE-KG-------SSIPKVEAK--------LIS----
------Y-----------------------M---TDQ---EVIQDL--WHLNDLLKSFHL
I--------------------------------------SFL------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQ-NY---LFSCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-SIKVT-LATLKMSVQPTLS-LGGFEITPP-V--VLRL-KC
GSGPLHI------I--------T-VEEDAESEDE-EEEDVKLL-SIS----GERSAPGGS
-SKVPQKKVKLAADEDDNEEDD---------D----------------------------
----------------------------------EDDE------------EA-EEKVK--
-KSIQDTPA-KNAQNSN-----QNGKDSKPSSTP-----------RSKGQEPFKK--QKK
---TPKTPKGPSSV EDSKAKMQASIE-KR-------DSLPKVEAK--------FIN----
------YV--KNCFQ---------------M---TDQ---EAIQDL--WQWRKS------
L--------------------------------------LKK------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQN-Y---LFGCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHLV--------A-VEEDAESEDE-DEEDVKLL-SMS----GKRSAPGGG
-NKVPQKKVKLDEDDDEDDE-----------D----------------------------
---------------------------------DEDDEDDDDDDFDDEEAEEK-VPVK--
-KSVRDTPA-KNAQKSN-----QNGKDLKPSTPR----------S--KGQESFKK--QEK
---TPKTPKGPSSV EDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MED----TDMDSMGSL----
--RPQ-TF---LFGCEL--KGDK-PFHFKVNDEEN----EHQLSLRT---VS-LGA--GA
KDDLH--VVEAEALDYEGN-QITVT-LASLKMSVQPTVS-LGGFEITPP-V--TLRL-KC
GSGPVYVS-GQHLV--------A-LEEEPESEDE-EDD--KVQ-HNM----AKRPAGVTL
-AKVPQKKAKLTEDDEDDDEDDEDDDEDDDDEED--DD----------------------
--------------------------------------DDMEEDEEEEKT-----PVK--
-KPARDLAV-KKTQKSN-----QNGKDSKPT-TP-----------KQKTPET----HKEK
KPQTPKTPK-TFTLEEIKAKMQAVVQ-KG-------TALPKAEAK--------FAN----
------YV--KNCYR---------------T---EDQ---KVIQAL--WQWRQTL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQN-Y---LFGCEL--KADK-DDHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELY--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGAFEITPP-V--VLRL-KC
GSGPVHIS-GQHL V--------A-VEEDAESEDE-EEEDVKLL-SIS----GKRSAPGGG
-SKVPQKKVKLAADEDDDD---D-------ED----------------------------
---------------------------------D-DDEDDDDDDFDDEEAEEK-APVK--
-KSIRDTPA-KNAQKSN-----QNGKDSKPSSTP-----------RSKGQESFKK--QEK
---TPKTPKGPSSV EDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFQ---------------M---TDQ---EAIQDL--WQWRNLN-----
---------------------------------------NLLKIFRLISFL---------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDI-DMSPL----
--RPQ-NY---LFGCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-LIKFT-LATLKMSVQPTVS-LGGFE-ITP-----------
----------PV----------------VVKL-----LS------IS----GKRSAPGGG
-SKVPQKKVKLAA-----------------------------------------------
-----------------------------------------A-----QETEG-KAPGK--
-KSIRDTPA-KNAQESN-----QDGKDSK-PSTP-----------RSKGRESFNK--QEK
---TPKTPKGPTSVEDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQ-NY---LFGCEL--KADK-DDHFKVDNDEN----EHQLSLRM---VS-LGA--GA
KDELH--IVEAKAINYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLHL-KC
GSGSVHTN-GQHL V--------A-VEEDAESEDE-EEEDVKLL-SIS----GKWSALGGG
-SKFPQKKVKLDADEEEDDD----------------------------------------
-----------------------------------NDEEDD-DDFDDEETEE-KVPVK--
-KSICSTP--------------------AK-NEK-----------I-----------P--
-----KTPKGPSSVEY IKANMQASIE-KG-------GSLPKVEAR--------FIN----
------YV--KNCFQ---------------M---TDQ---EAIQDV--WQWRNL------
N--------------------------------------NLLKVFRLISFL---------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MEE--SMDM-DMSPS----
--RPQ-NY---LSGCEL--KADR-DYPFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDGLH--IVEAEAMDYEGG-PTEVT-L--------PTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHLV--------A-AEEDAGSEDK-EEEDVKLL-SIS----GKRSAPGSG
-SKVPQKKVKLAAAEEDVDD----------------------------------------
----------------------------------------EDDDNFDEEVEEK-APVE--
-KSVRDTPG-KNAQKSN-----QNGKDS-KRSTP-----------RSKGQGSFKITGKKK
---TPTTPKGPSSVLKTL--KTDSLE-KA-------LMLGKIEGK--------RRR----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQN-Y---LFGCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHL V--------A-VEEDAESEDE-EEEDVKLL-SIS----GKRSAPGGG
-SKVPQKKVKLAADEDDDDEDDD-------D-----------------------------
---------------------------------DDDEDDDDDDEFDDEETEEK-APVK--
-KSVRDTPA-KNAQKSN-----QNGKDSKPSTPR----------S--KGQESFKK--QEK
---TPKTPKGPSSV EDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSLL----
--RPQ-NY---LFGCEL--KADK-DYNFKVDNDEN----EHQLSLQT---VS-LGA--GA
KDELH--IVEAEAMNYKGS-PIKVT-LATLKMSVQPMLS-LGGFEITPP-V--VLKL---
------------------------------------------L-SMS----GKHSTPGGG
-SKVPQKKVKLAADENDEDDEK---------D----------------------------
--------------------------------------DDDDDDFDDEEAKEK-APEG--
-KTTAFRGS-EEAQCGKFKASRPGGQIPLVL--T-----------TTKKKKRKKKKDSKP
---STPRSKGPSSVENIKAKMQTNIE-KD-------GSLPKVEAK--------FINY---
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQ-NY---LFGCEL--KADK-DYHFKVDNDEN----EHQLSLRM---VS-LGA--GT
KNELH--IVEAEAMNYEGS-PIKVT-LATLKMSMQPTVS-LEGFEIISP-V--VLQL-KC
GSGPVHIS-GQHL V--------A-VEEDAESEDE-EDEEVKLL---------------SG
-SKVPQKKVKLAADEDD-------------------------------------------
--------------------------------------DDDDDDFDDEETEE-KTPVK--
-KSVRDTPA-KNAQKSN-----QNGKDSK-PSTP-----------RSKGQESIKK--QEK
---APKTPKGP TS-----------IE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WHLNSLLKVFRL
ISFL--------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQ-NY---LFGCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTWC-GSGPVHISG-T--VEVA-V-
-------S-QDC----------------AISPED-EEEEDVKL-LMS----GKRSAPGGG
-SKVPQVEMAILFD----------------------------------------------
----------------------------------------DDDDFDDEETEE-KVPVK--
-KSIRDTPA-KNAQKSN-----QNGKDSK-PSTP-----------RSKGQESFKK--QEK
---TPKTPKGPSSVEDIKAKMQASIE-KG-------GSLPKVEAK--------FVN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------IED--SMDM-DVSPL----
--GPQ-NF---L------------------------------LSLRS---VS-LGT--CA
KDELH--IVETEALHYEGS-PIKIT-LATLKMCEEPMVS-LGDFEITLP-V--VLQL-KC
GSGPVHIS-GQH SI--------T-VEEDAESEDE-EEEDVKVL-SIS----GKRSAPWK-
---FHGKKMKPAADK---------------------------------------------
------------------------------------DDDEDDDDFDDDKSEEK-SPVK--
-KSIGDTAA-KSAQKSN-----QNGKDSKPS-TP-----------RSKGQESFKK--QEK
---TPKTPKEPSSV EDIKAKMQANIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFP---------------M---TGQ---EAIQEI--------------
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQ-NY---LFGCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDKIH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHLV--------A-VEEDAESEDE-EEEDVKLL-SIS----GKRSAPGGG
-SKVPQKKDDEED--------E---------D----------------------------
----------------------------------EDEDD-DDDDFDDEE-T---------
-------------EEKA-----PNGKDLKP-STP-----------RSKGQESFKK--QEK
---TPKTPKGPSSVEDIKAKMQASIE-KV-------SGLIFCH-----------------
------------------------------V---SNC---TSIQEL--WNMIER------
Q--------------------------------------NKNV-----------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPP----
--AAP-DY---LFGCEL--KADK-DYHFKVDSDEN----EHQLSLRM---VS---L--GA
KDELH--IVEAEEGSPIKV-TLPTL-------KMSATVS-FGGFEITPS-V--VFRL-KC
GSGPVHIS-GQHLV--------A-VEEDAESEDE-EEEDVKLL-SIS----GKRSAPGS-
------KKVKLAADEDVD------------------------------------------
--------------------------------------EDDDDDSDDEETEEK-APVK--
-KSIRDTPA-KNAQK-N-----QHGKDSKPS-TP-----------RSKGQESFKE--QEK
---TPKTLKGPSSVEDIKGKMEASIE-KG-------GSLPK-EAT--------FIN----
------YV--KNCFR---------------M---TDR---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------ISACCPSMED--SMNM-DMSPL----
--RPQ-SY---LFNCEP--KADK-DDHFKVNDDEN----KHQLSLRT---VS-LGA--GA
KYELH--IVEAEAMNYKGS-PIKVT-LATLQMSVQATVS-LGGFEIPLP-V--VLQL-KC
GLGPVHIS-GQHLV--------A-VEEDADSEDE-VED----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------MNYEGS-PIKVT-LATLKMSVQPVVS-LGGFEIIPP-V--LLWL-KC
GSGPVHIS-GQHL V--------V-VEEDAESEDE-EEEGVKLL-S-------GS------
--RVPQKKVKLAANEDE----E---------D----------------------------
-----------------------------------D------DDFDDEEAEE-KAPVK--
-KSIQDISA-INAQKSN-----QNGKDSKA-STP-----------RSKGQESFKN--QEK
---TPKTPKGHSSV EDIKAKMQANIE-KG-------GSLPKVEAT--------FIN----
------YV--KNCFW---------------M---IDQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQN-Y---LFGCEL--KDDK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGR-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHL V--------A-VEEDAESEDDDEEEDVKLL-SMS----GKRPAPGGG
-SKVPQKKVKLAADEDEDDEDED-------------------------------------
-----------------------------------DDDDDGDDDFDDEETEEK-VPVK--
-KSIRDTPA-KNAQKSN-----QNGKDSKPSSTP-----------RSKGQESFKK--QEK
---TPKTPKGPSPV EDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFQ---------------M---TDQ---EAIQDL--WQWRNLN-----
---------------------------------------NLLKIFRLISFL---------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SVDM-DMSPL----
--RPQ-NH---LFSCEL--KAHR-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
EDELH--MVEAEAMNFEGS-PIKVT-LATLKMSVQPTVS-LGGS GPV-------------
-----------------------------------HIKEVKLL-SIS----GKRSAPGSG
-SKVPQKKVKLAADEDE-------------------------------------------
----------------------------------DD------DNDDNEEGEEK-APVK--
-KSVRDTPA-KNAQKPN-----QNGKDSKLS-TP-----------RSKGQESFKK--QEK
---RPSSVE------DIKVKMQASIE-KG-------GSLPKVEAK--------FIH----
------YV--RNGFR---------------M---TDQ---EAIQDV--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--LMDR-DMSPL----
--RPQ-NY---LFSCEL--KADK-DDHFKVDNDEN----EHQLSLRT---VS-LGP--GA
KDELQ--IIEAEAMNYEVT-LATL---------KIF--------EITHP-V--VLRL-KC
GSGPVYIS-GQHLV--------A-VVEDAESEDE-EEEDVKLL-SIS----GKQSATGGG
-RRVPQRKVKLAADEDDDDEHD---------D----------------------------
--------------------------------------DEEDDDFDDEESEEK-APVK--
-QSIRDTL-----------------E---------------------------------K
---TPKTPKGPSSVEDIRAKMEASIE-KV-------H-----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RSQ-NY---LFG---------------LDNDEN----EHQLSLRT---VS-LRV--GA
KDELH--IIEAEAMNYEGS-TIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VFRL-RC
GSGPVHIG-GQHL V--------A-VDED---------EEMKLL-SMS----GKRSAPGGG
-SKVPQKKVKIDEEEEDEDEHD---------E----------------------------
--------------------------------------DNDDDDFDDEET------VK--
-KYVRDTPA-KRAQKSN-----QNGKNLNYQKVK-----------SP-------SKNRKI
---TPKTPKGPSSV EDIKAKMQASIE-KG-------GSLPKMEAH--------SPD----
------LS------------------------------------------WT--------
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RP------------------Q-NYLFRVDNDKN----EHQLSLRT---VS-LGV--AA
NDELH--IVEAEAMSYKGS-PIKVT-LATLKMSVQPTVS-LGGFEITPT-V--ILRL-KC
GSGPLHIR-GQHL V--------A-VEEDAESDDE-EEEDVKLL-SIS----GKQSALGSG
-SKVPQKKVKLAADEDDDDD----------------------------------------
------------------------------------------DDFDDEEIEE-KAPVK--
-KSI-DTPA-KNAQKSN-----QNGKDSKP-STP-----------RSKGQESFKK--QEK
---TPKTPKGPSSVKY IKAKIQASIE-KG-------GSLVKVEAK--------LVN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------PTD--NTDM-DVNHI----
--RAQ-SF---LFGCEL--KADK-DFHFKVGNEQT----EHQLSLKT---VS-LGA--SA
KDELH--VVEAEALNFEGS-PTTVT-LASLKLSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVYVS-GQHLV--------A-LEEDVE-----ENN-VKVV-NLP----AKRAASEAD
-DKIPPKKVKLSEEEEEEEEEEEEEE----------------------------------
--------------------------------------EDDDEAEEEEEIEEN-NPLENK
SNPDSPAQN-GEMPNLE-----EETTDSEPV-TP-----------KSKSQESFDTEEK--
---VSPSPQEASSPEDVKEIQASTEK-KK-------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MDD--L--M-DMSPL----
--RPQ-NY---LFGCEL--K---------VDNDEN----EQQLSLRM---VS-LEA--GA
KDELH--IVETEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPL-V--VLRL-NC
GSGPVHIS-GQHL V--------A-GEEDTESEDE-EEEDVKLV-SIS----GKQSVPGGG
-SKVPQKKVKLAADEDDD------------------------------------------
---------------------------------------DD-DDFDDEETEE-KALVK--
-KSIQDTP--------------------AK-NEK-----------T-----------P--
-----KAPKGPSSV EDIKAKMQATIE-KG-------GSLPKVEAS--------SSI----
------M-----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQ-NY---LFGCEL--KADK-DYHFKVDNDEN----EHQLSLRM---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VVRL-KC
GSGPVHIS-GQHL V--------A-VEEDAESEDE-EEEDVKLL-SIS----GS-------
--WLCPGG-------GN-------------------------------------------
----------------------------------DDDDEDD-EDVMM------M------
---------------IL-----MMRKLKTS-STP-----------RSKGQESFKK--QEK
---TPKTPKGPSSV EDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRSL------
F--------------------------------------KKIV-----------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQN-Y---LFGCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHL V--------A-VEEDAESEDE-EEEDVKLL-SIS----GKRSAPGGG
-SKVPQKKVKLAADEDDDDDD---------ED----------------------------
---------------------------------D-DDEDDDDDDFDDEEAEEK-APVK--
-KSIRDTPA-KNAQKSN-----QNGKDSKPSSTP-----------RSKGQESFKK--QEK
---TPKTPKGPSSV EDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--LMNM-DMSPL----
--RPQ-NY---LFGCEL--KADK-DYHFKVDNDEN----EHHLSLRM---VS-LGA--SA
KDELH--IVEAEAMNYEGS-PIKVT-LASWKMPEQQPVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHL V--------A-VEEDTESEDE-EEEDVKLL-SIS----GKWSAPGGG
-SKIPQKKVKLADEDDED------------------------------------------
----------------------------------------------DEETEE-KPPVK--
-KSIRYSSQ-KCTK-----------------IKP-----------EWKGQESFKK--QEK
---TPKTPKGPSSV EDIKAKMQASIE-EG-------GSLPKVEAK--------FIN----
------Y---------------------------------EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--LMDV-DMSSL----
--RPQ-NY---LFGCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYKGS-PIKV---------IQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHLV--------A-VEEDAESEDE-EEDDVKLL-SIS----GKRSALGGS
-SKFPQKKVKLAADEDDDDDDD---------D----------------------------
---------------------------------E-DDDDEDDDDDFNEEAEEK-LPVK--
-KSIQDTPD-KNAQ----------------------------------------------
-----------NSVEDIKAKMQASIE-KA-------H-----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------S-------SPHS--TLEMSPTRNH----
--EPQ-KY---LFSCEL--KVYK-DYHFKVDNDEN----VYLLSLRM---VS-LGS--SA
QDKLH--FVEAETMNYEGI-PIKVT-LEVLKMSVQPMVS-LGGFEITPP---------AC
GSGPVHIS-EQHLV--------A-VEEDAESEDE-EKEDMKLL-SIS----GKCSPTGGG
-IKFPGKKSKTYDDEDDGD-----------------------------------------
---------------------------------------DEDRYFNQKCTKIK-QEWK--
-D-------------SK-----L-------L-TP-----------RSKGQKFFKKQE---
--KTPKTSKGPSSVEDIKAKMQSGIEKLP-------TG----------------KN----
------YP--M-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMHM-DMSPL----
--RPQ-NY---LFGCEL--KADM-YYYFKVDNDEN----EHQLSLRM---VS-LGA--GA
KDELH--IVEAVAMNYEGS-PIKVT-LATLKMSVQPTVS-LGSFEITPP-V--VLRL-KR
GSGPVHIS-GQHL V--------A-IEEDAESEDE-GEEDVKLL-SMS----GKRSAPGGG
-NKVLWKRLKTTNT----------------------------------------------
------------------------------------------------------------
---------------------------------------------KIKGSRVFQRT-GKG
---TPKTPEGASSV DDIKAKMQTSEE-RS-------ASLLKVEAK--------FI-----
-----NYVK--NCFR---------------M---TDQ---EAVQDL--WQWRKSKKTFKQ
F--------------------------------------EIFR----LT-----------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--AMDT-DMSPL----
--RPR-NY---LFGCEL--KADK-DDHFKVDNDEN----KHQLSLRM---VS-LGA--GA
KDELH--IVEAQAMNYEGS-PTKVT-LATLKMSLQPMVS-LGGFEI---------TP-PC
GSGPVHIS-GQHLV--------A-VEEDAR-EDE-EEGDVKLL-SIS----GNRLAPGGG
-SKFPQKKVKLAADEDDD------------------------------------------
------------------------------------------DDFDDAETKEK-VPV---
---------------------------LKTIINT-----------KIKRTRILQKT-GNK
---TPKTPKGPSSVEDVKAKMQASIE-KG-------GSQPGTVA----------------
----------QACNP---------------S---TLGGRDGRITRS--GD-RDHPG----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQN-Y---LFGCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHL V--------A-VEEDAESEDE-EEEDVKLL-SIS----GKRSAPGGG
-SKVPQKKVKLAADEDDDDDE---------ED----------------------------
---------------------------------D-DDEDDDDDDFDDEEAEEK-APVK--
-KSIRDTPA-KNAQKSN-----QNGKDSKPSSTP-----------RSKGQESFKK--QEK
---TPKTPKGPSSV EDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--LMDM-NMSPL----
--RPQ-NY---LFGCEL--KADK-NYQSKVDNDEN----EHQLSLRT---VS-LGA--GA
EDELH--IVEAEATNYKGS-PIKVT-LATLKMSVQPTVS-LGGFKVTPP-V--DLRL-KC
GSGPVHIS-GQHLV--------A-VEEDAESEDE-EEEDVKLL-TVS----GKRSAPGGG
-SKVPQKKVKLAADEDEDEDED---------D----------------------------
---------------------------------D-DEDDDD--DSEDEEA----------
------------------------------------------------------------
------KEKGTSSVEDIKAKMQASIE-KA-------HSTAPDCAV--------CGNGK--
----K-------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQN-Y---LFGCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHL V--------A-VEEDAESEDE-EEEDVKLL-SIS----GKRSAPGGG
-SKVPQKKVKLAADEDDDDDD---------EE----------------------------
---------------------------------D-DDEDDDDDDFDDEEAEEK-APVK--
-KSIRDTPA-KNAQKSN-----QNGKDSKPSSTP-----------RSKGQESFKK--QEK
---TPKTPKGPSSV EDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------LK----
--AD------------------K-DYHFKVDNDDN----EHQLSLRT---VS-LGA--GA
KDELH--SVEAEAMNDEGG-PIRVT-LATLKMSAQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHL V--------A-VEEDAESEEE-EEEDVKLL-SIC----GKRSAPGGG
-SKVPQKKVKLTADEDDEDDED---------E----------------------------
-----------------------------------D-EEDEDEEEDDEETEE-KAPVK--
-KSIRDTPA-KNAQKSN-----QNGKDSKP-STP-----------RSKGQESFKK--QEK
---SPKTPKGPGSV EDIKAKTQAGIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------MNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQH LA--------V-AEEDAESGEE-EEEDVKLL-SIS----GKR------
--SVPQKKVKLAADEDDDDDDD---------D----------------------------
-----------------------------------DDDEDDDDDFDEEEAKE-KA-----
----------------------PNGKDSKP-STP-----------RSKGQESFKK--QEK
---TPKKPKEPSSV EDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YM--KNCFR---------------I---TDQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQ-NY---LFGCEV--KAGK-NYHFKVDNDEN----EHQLSLRT---VR-LGA--GA
KDELH--VAEAEAMNYEGR-PIKVT-LATLKMSVQPTVS-LGGFEITLP-V--VLRA-KC
GSEPVHVS-GQHL V--------A-VEGDAESGDE-KEEDVKLL-SIS----G--------
-NKVPQKKVKLAADEDDDDEDD---------D----------------------------
------------------------------------EEEDD-DDFDDEDTEE-KAPVK--
-KSIRDTP-------------------------------------AKNGQESFRK--QEK
---TPKTPKGPSSV EDIKAKMQASIE-KG-------ASLPKVEAK--------FID----
------YV--KNCFR---------------M---TDQ---EAVQDL--WQWRNL------
N--------------------------------------SLLKFSILFHFCNS-------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQ-NY---LFGCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQLTVS-LGGFE-ITP-----------
----------PV----------------VVKL-----LS------IS----GKRSAPGGG
-SKVPQKKVKLAA-----------------------------------------------
-----------------------------------------E-----EETEE-KAPVK--
-KSIRDTPA-KNAQKSN-----QNGKDSK-PSTP-----------KSKGQESFKK--QEK
---TPKTPKGPTSVEDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQN-Y---LFGCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VVRL-KC
GSGPVHIS-GQHL V--------A-VEEDAESEDE-EEEDVKLL-SIS----GKRSAPGGG
-SKVPQKKVKLAADEDDDDDD---------------------------------------
------------------------------------EDDDDDDDFDDEEAEEK-APVK--
-KSIRDTPA-KNAQKSN-----QNGKDSKPSSTP-----------RSKGQESFKK--QEK
---TPKTPKGPSSV EDIKAKMQASIE-KG-------GSLPKVEAK--------LKI----
------MT--TKKYM---------------A-----------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQN-Y---LFGCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHL V--------A-VEEDAESEDE-EEEDVKLL-SIS----GKRSAPGGG
-SKVPQKKVKLAADEDDDDDD-E-------D-----------------------------
-----------------------------------DDDEEDDDDFDDEEAEEK-APVK--
-KSIRDTPA-KNAQKSN-----QNGKDSKPSSTP-----------RSKGQESFKK--QEK
---TPKTPKGPSSV EDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRNLN-----
---------------------------------------NLLKIFRLISFL---------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQN-Y---LFGCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-RC
GSGPVHIS-GQHL V--------A-VEEDAESEDE-DEEDVKLL-SMS----GKRSAPGGG
-SKVPQKKVKIDEDEDDDDE-----------D----------------------------
---------------------------------DEDDEDDDDDDFDDEETEEK-VPVK--
-KSVRDTPA-KNAQKSN-----QNGKDLKPSTPR----------S--KGQESFKK--QEK
---TPKTPKGPSSV EDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQN-Y---LFGCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHL V--------A-VEEDAESEDE-EEEDVKLL-SMS----GKRSAPGGG
-SKVPQKKVKLAADEDDDDDEDD-------D-----------------------------
---------------------------------DDDDEDDDDDDFDDEETEEK-VPVK--
-KSIRDTPA-KNAQKSN-----QNGKDSKPSSTP-----------RSKGQESFKK--QEK
---TPKTPKGPSSV EDIKAKMQASIE-KG-------GSLPKVEAN--------FVF----
------LV--EMGFT---------------L---LAR---LVLNF---------------
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------GCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHL V--------A-VEEDAESEDE-EEEDVKLL-SVS----GKRSAPGGG
-SKVPQKKVKLAEEDEEEED--E-------------------------------------
---------------------------------DDDEEEDDDDDFDDEEAEEK-VPVK--
-KSIRDTPA-KNAQKSN-----QNGKDSKPA-TP-----------RSKGQESFKK--QEK
---TPKTPKGPSSV EDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MRD--LMDM-DMSPL----
--RPQ-I-------CEL--KADK-DYHFKVDNDEN----EHKLSLKT---VI-LGV--GA
KDELH--IVKAKAMKYKGS-LMQVT-LENLKMSVAKI-S-LVGLEITPP-V--VL-R-KA
KLGAVEMM-----I--------K-IEEEE-EEGE-EGEEGEEE-GEE----EGEEGEEEG
EEDGEEKEEEEEEEEEEEEEEEEEEEEEEEEGRGGGVE----------------------
--------------------------------EEGGGGDDDDDHNDEEEAEEK-APVK--
-NLYEILHQ--------------NCKPLKTI-HM-----------KIKRYRINRT-----
GKTFLKTPKGPSSVEDIKTKMQVSIE-KG-------GFLSRVEAK--------FIN----
------YV--NNCFQ---------------M---TDQ---EFIQDP--QHWRNLF-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-MHTEHSWYDSVLRGC---SVGQRWFISVRLLSHRSACRHLIED--AMDV-DMSSP----
--RPQ-NS---LFGCEL--KANK-DDHFKVDNDEN----EHQLCLRT---VS-LGA--GA
KDELY--VVEAEAMNYEGS-PIQVT-LATLKMSAVPTVS-LVGFEITPP-V--VLRL-KC
GSGPVHIS-GQHL V--------A-VEEDAESEDE-EEEDVKLL-SIS----GKRSAPGSG
-SKVPQKKVKLAAAEDDDEDND---------D----------------------------
--------------------------------------EED-DDFDDEEAEE-KAPK---
---SKQKGK-DS---------------KPS-SAP-----------RSKGPESFQK--QEK
---SPKTPKRPSSV EDSKAKMQASIE-KG-------GFLRRVEAK--------FIN----
------YV--KNCFR---------------T---TEQ---EAIQDL--WQWRNL------
N--------------------------------------NLLKIFRLISFL---------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSVL----
--RPQ-NY---LFSCEL--KTKK-DYHFKL-------------SLRT---VS-VGT--GA
KDELN--TVEAEAVNYKDS-PIKVT-LATLKMSVQPTVS-PG-----------ALRL-KC
GSGPVHIS-GHLVA--------V-EEDAESDEEK----EEKNS-SIS----GKRSVP---
-----GSVKLAADEDDDD------------NND---------------------------
-------------------------------------NDDDDNDFDNEETEKK-------
----------------A-----PNGKDSKLS-TP-----------RSKGQESFKK-----
QEKTPKTPNGLSSVENIKTKMQASIE-KK-------H-----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MKD--SMDM-DMSPL----
--RPQ-NY---LFGCEL--KADK-DYHFKVDNDEN----E------T---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPMVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHLV--------A-VEEDAESEDE-EEEDVKLL-SMS----GKRSAPGGG
-SKVPQKKVKLAADEDDDDDD---------------------------------------
--------------------------------------EDDDEEEEEEETEE-KVPVK--
-KSICDTPA-KNAQKSN-----QNGKDSKPSSTP-----------RSKGQESFKK--QEK
---TPKTPKGPSSVEDIKAKMQASIE-KG-------DFAVLISPS--------FNVEF--
------------------------------------T---GLFSF---------------
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MKD--SMDM-DMSPL----
--RPQN-Y---LFGCEL--KADI-DYHFKGDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAQAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHL V--------A-VEEDAESEDG-EEEDVKLL-SMS----GKRSAPGGG
-SKVPHKKVKLAADEDDE------------------------------------------
---------------------------------------DDDDDFDDKETEEK-EPVK--
-KSIHDTPA-KNAQKSN-----QNGKDSKPSSTP-----------RSKGQESFKK--QEK
---TPKTPKGPSSA EDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDL---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQ-NY---LFGCEL--KADK-DYHFNLDNDEN----DHQLSLIT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVSLGG-FEITPP-V--VLRL-KC
GSGPVHIS-GQHLV--------XXXXXXXXXXXX-XXXXXXXX-XXX----X--XXXXXX
-XXXXXXXXXXXXXXXXXXXXX---------X----------------------------
---------------------------------XXXXXXDDDDDFDDEEAEE-KAPVK--
-KSIRDTPA-KNAQKSN-----QNGKDSKPS-TP-----------RSKGQESFKK--QEK
---TPKTPKGPSSVEDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MEY--SVDT-DMSPL----
--RPQN-C---LFGCEL--KANK-DYHFKVDNDEN----KHQLSLRM---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHL V--------A-VEEDAESEDE-EEEDVKLL-SMS----GKRSAPGGG
-SKVPQKKVKLAAVEEDDDDDDD-------------------------------------
------------------------------------------DDEDDEETEEK-VPAK--
-KSIRDTP--------------------------------------------------EK
---TPKTPKGPSSV EDIKAKMQASIE-KG-------GSLPKVEAK--------FIS----
------YV--KNCFQ---------------M---TDQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQ-NY---LFSCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAVNYEGS-PIKVT-LATLKMSVQPVVS-LGGFEITPP-V--DLRL-KC
GSGPVHIS-GQHL V--------A-VKEDAESEDE-EEEDVKLL-SIS----GKQSAPGGG
-QKK----VKLAAAADDDDEDD--------------------------------------
----------------------------------DEDDD-DDDYDDEEA-EE-KAPVK--
-KS---TPA-KNAQKSN-----QNGKDSKPSSTP-----------RSKGQESFKK--QEK
---SPKTPKGS----NIKAKMQANVE-KG-------GSLPKVETK--------FIN----
------YV--KNFFW---------------M---TDQ---EAIQDL--WQWRNL------
N--------------------------------------NLLKIFHLISFL---------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--LMDM-NMSPL----
--RPQ-NY---LFGCEL--KADK-NYQSKVDNDEN----EHQLSLRT---VS-LGA--GA
EDELH--IVEAEATNYKGS-PIKVT-LATLKMSVQPTVS-LGGFKVTPP-V--DLRL-KC
GSGPVHIS-GQHL V--------A-VEEDAESEDE-EEEDVKLL-TVS----GMRSAPGGG
-SKVPQKKVKLAADEDEDEDED---------D----------------------------
----------------------------------DD-EDGD-DDSEDEEAKE--------
------------------------------------------------------------
--------KGTSSV EDIKAKMQASIE-KG-------GSLRRVEAR--------FIS----
------YV--KNCFW---------------M---IDQ---EAIQDL--WQWRNL------
N--------------------------------------NLLKIFLLILFL---------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMGM-DMSPL----
--GPQ-NC---LFGCEL--KADK-DYHFKVDNDEN----EHQLSLRT---V---------
-NKLH--IIEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHL V--------A-VEEDAESGDE-DEEDV--------------------
----LQKKVKLDEDGEDEDG----------------------------------------
----------------------------------DDDDDDD-DDFDDKEAEE-KVPVK--
-KS---------------------------------------------------------
------------------AKMQASIE-KD-------DSLPKVEAK--------FIN----
------YV--KNCFQ---------------I---TDQ---EVIQDL--WQWRKS------
L-----------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQN-Y---LFGCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHLV--------A-VEEDAESEDE-EEEDVKLL-SIS----GKRSAPGSG
-SKVPQKKVKLAADEDDDDDDDD-------------------------------------
---------------------------------DDDDEDDDDDDFDDEEAEEK-APVK--
-KSIRDTPA-KNAQKSN-----QNGKDSKPSTPR----------T--KGQESFKK--QEK
---TPKTPKGPSSVEDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DVSPL----
--RPQN-Y---LFGCEL--KANK-DYHFKVDNDEN----EHQLSLRT---VS-SGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKTSVQPTVS-LGGFEITPPPM--GLRL-KC
GSGPVHIS-GQH LE--------A-VEEDAESDED-EEEDVKLL-SIS----GKQSAPGSG
-SKVPQKKVKLAADEDDDDDDDD-------------------------------------
------------------------------------------------------------
-----DTPA-KNAQKSN-----WNGKDSKTSTP------------RSKGQESFKK--QEK
---TPKTPKGPSSV EDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EATQGL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------MNYEGS-PIKVT-PAALKMSVQPTVS-LGGFEIPPP-V--VLRL-KC
GSGPVHIG-GQHL V--------A-VEEDAESEDE-EEEDVKLL-SIS----GKWSAPGG-
-SKVPQKKVKLAADEDDDDEDD---------D----------------------------
--------------------------------------NDD-F-YEEAEE----------
--------------------------------KN-----------QSKGQESFKK--QEK
---NPKTPKGPSSV EDIKAKMQASIE-KG-------GSLPRVEAK--------FIN----
------YV--KNCFR---------------T---TEQ---EAIQDL--WQWRKS------
L-----------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------MNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLWL-RG
GSGPVHIS-GQHL V--------P-VEEDAESEDE-DEEGVKLL-SMS----GKRSAPG--
---VPQKKVKIDEDEDD-------------------------------------------
------------------------------------------DDFEDEETEE-KVPVK--
-KFVRDTPA-KNAQKSN-----QNGKDLKL-STP-----------RSKGQESFKK--QEK
---TPKTTKGPSSV EDIKAKMQASIG-KG-------SSLP----K--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQ-NY---LFN-----------DHFKVDNDED----EHQLSLRM---VS-LGA--GA
KDELH--TVEAEAMNYKGS-PIKVT-LATLKMSVQPMVS-LGGFEITPP-V---------
---------GQHLV--------A-VEEDARK-DE-EEEDVKLL-SVS----GKRSAPGGG
-SKVPQKKVKLAADEDDDYEDD---------D----------------------------
----------------------------------DDDEDDDNDDFDDKETKE-KAPVK--
-QSIRDTPA-KNAQKSN-----QNGKDSKPSSTP-----------RSKGQESFKK--QEK
---TPKIPKGPSSV EDVKANMQARIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--------------
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DVSPL----
--RPQ-NY---LFGCEL--KANK-DYHFKVDNDEN----EHQLSLRT---VS-SGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKTSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHL V--------A-VEEDAESDEE-EEEDVKLL-SIS----GKQSAPGSG
-SKVPQKKVKLAADEDDDDDDD---------D----------------------------
----------------------------------DTPAKNA-QK----------------
---------------------------------S-----------NWNGKD------SKT
---STPRSKGPSSV EDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EATQGL--WQWRKS------
L-----------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------MGM-DMSSL----
--RPQ-NY---LFSCEL--KADK-DYHFKVANDEK----EHQLSLRK---VS-LGA--GA
KDELH--MVEAEEMNYEGN-PIKVT-LATLKMPIQPTVS-LGGFEITPP-V--VLWL-RC
GSEPVHIS-GQH LA--------A-VEEDSESEDE-DEEDVKLL-SMS----GQRSAPGGG
-SRVPQKKVKINEDEDEDDE----------------------------------------
----------------------------------------DDEDDGDEEIEE-KVPVK--
-KSVCDTPA-KNAQKSN-----QNGKDLKPST-P-----------RSKGQ--------EK
---TPKTPKGPSSV EDIKEKMQASIE-KG-------GSLPKVEAK--------F------
--------------------------------------------IN--YQWRRSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MEH--SMDM-NMSPL----
--RTQ-NY---LVSCEL--KADK-DDHFK-----------HQLSLRT---VS-LEA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LPTVS---------LGGFEITPP-V--VLRL-KC
GSGPVHIS-VQHL V--------A-VEEDAESEDE-EKEDVKLL-SIS----GKQFAPGGG
-SKFPQKKVKLAADEEDDDDEE---------D----------------------------
---------------------------------NDDED-DDDDDFDDKEAEE-KLPVK--
-KSIQDTPA-KNAQKSN-----HNGKDSKLSSAP-----------RSKRQDSFKK--QEK
---TPKTPKGPSSV EDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------V---TDQ---EAIQDL--WQWRNLNNLL--
------------------------------------------KIFHLISFL---------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQN-Y---LFSCEL--KADS-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAKAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHLV--------A-VEEDAS-EEE-EEEEVKLL-SIS----GKRSAPGSG
-SKVPQKKVKLAADEDEDDDDD--------DD----------------------------
---------------------------------DDDEEDDDDDDFD-EEVEEK-APVK--
-KSVRDTPA-KNAQKSN-----QNGKDSKPSTPR----------S--KGQESFKK--QEK
---TPKTPKGPSSVEDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRKSL-----
---------------------------------------LLKIFRLIS--F--------L
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DINPW----
--RPR-NY---LFGCEL--QADK-DYHFKVDNDEN----E------T---VS-LGA--DG
KDELH--IVEAEAVCYEGS-PIKVT-LATLKMSVQPTIF-LRGFEITQP-V--VLRL-KC
GSGPVHIS-EQHL V--------A-VEED-------AEEDVKLL-SIS----GKWSAPGGG
-SKVPQKKVKLATDEDDDD-----------------------------------------
-----------------------------------NDEDDDNDDFDNEETEEK-AP----
-----------------------NGKD-------------------------------SK
---PSSTPRSNGSV EDIKAKMQASIE-KG-------GSLPKVEAK--------FIS----
------YM--KNCFR---------------M---TDR---EAIQDL--WQLRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQN-Y---LFGCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHL V--------A-VEEDAESEDE-DEEDVKLL-GMS----GKRSAPGGG
-NKVPQKKVKLDEDDEDDDE-----------D----------------------------
---------------------------------DEDDEDDDDDDFDEEETEEK-VPVK--
-KSVRDTPA-KNAQKSN-----QNGKDLKPSTPR----------S--KGQESFKK--QEK
---TPKTPKGPSSV EDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQN-Y---LFGCEL--KADR-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHLV--------A-VEEDAESEEE-EEEEVKLL-SIS----GKRSAPGSG
-SKVPQKKVKLAADEDEDDGDDD-------DD----------------------------
---------------------------------NDDEEDDDDDDFD-EEVEEK-APVK--
-KSVRDTPA-KNAQKSN-----QNGKDSKPSTPR----------S--KGQESFKK--QEK
---TPKTPKGPSSVEDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRKSL-----
---------------------------------------LLKIFRLIS--F--------L
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SVDM-DMSPL----
--RPQ-NY---LFSCEL--NANK-DYHFKVDNDEN----E------T---VC-LGA--GT
KDELH--MGEAEAMNYKGS-PIKVT-LATLKMSVQPTVC-LGGFQITPP-F--VLRL-KY
ASEPVHIS-GQHL V--------A-VEENAESDAE-EEEDVKLL-SIS----GKGSAPGSG
-SKVPQKKVKLAADEEKSSSE---------------------------------------
-------------------------------------EI----------------DEI--
-LQPKISKG-QEY----------FKKQ-------------------------------EK
---TPQTPKGPSSV EDIKAKMQASIE-KG-------GSLPKVETK--------FIN----
------YV--KNYFR---------------M---TDQ---EAIQDL--WQWRKSLLENNL
N--------------------------------------SLLKFSVLFHFCNS-------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQN-Y---LFGCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHL V--------V-VEEDAESEDE-EEEDVKLL-SMS----GKRSAPGGG
-NKVPQKKVKLAADEDDDEDEDD-------------------------------------
---------------------------------DEDDEDDDDDDFDDDEAEEK-APVK--
-KSIRDIPA-KNAQKSN-----QNGKDSKPSTPR----------S--KGQEAFKK--QEK
---TPKTPKGPSSV EDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQN-Y---LFGCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHL V--------A-VEEDAESEDE-EEEDVKLL-SIS----GKRSAPGGG
-SKVPQKKVKLAADEDEDDDEDD-------------------------------------
---------------------------------DDDDEDDDDDDFDDEEAEEK-APVK--
-KSIRDTPA-KNAQKSN-----QNGKDSKPSTPR----------S--KGQESFKK--QEK
---TPKTPKGPSSV EDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EVIELS--GDMTNSK-----
---------------------------------------IYCDLLHYL--FSLFRCWLLL
KG-----S----------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQ-NY---LFGCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVESEAMNYEGS-PSKVT-LAILKMSVQLTVY-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHL V--------A-VEEDAESEEE-EEEDVKLP-SIS----GN-------
--KIPQKKVKLTADEDD-------------------------------------------
----------------------------------EDDDDDD-DDNDDDDDDE--------
-----------ETEEKA-----PNGKDSKP-STP-----------RSKGQESFKK--QEK
---SSKALKRPSSV EDIKAKMQASIE-KG-------VSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRKS------
L-----------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQ-NY---LFICEL----------------------------RT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LPTVS---------LGSFEITPP-V--VLQL-KC
GSGTVHIS-GQHL V--------A-VEEDAESEGE-EEEDVKLL-SIS----EKRSAPGGG
-SKFPQKKVKLAAEEDDDDDDD---------D----------------------------
---------------------------------EDDGDDDDDNDEDNEEAEE-KAPVK--
-KSIQDTPA-KNVQKSN-----ENGKDSKPSSTP-----------RSKGQESFKK--QEK
---TPKTPKGPSSV EDIKAKVQASIE-KG-------DSLPKVAAK--------FIN----
------YV--KNCFQ---------------M---TDQ---EAIQDL--WQWRNLNNLL--
------------------------------------------KIFHLISFL---------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MEK--SVDM-DMNSL----
--RPQ-NA---FW-FEV--KTDR-NYHFEMDNNEN----EHQLSLRM---VS-LGA--GA
KYELH--IIEAEAMNHESS-PIHSN-TGNFENVHTAIGF-PGGFEITHI----VLQL-QC
DSGTVQIN-GKHSV--------D-VGEA-KSEDE-EEEDVTQKIFLGHSVYLESNLPPEL
VANFHRKKRKLAADEDGD------------------------------------------
--------------------------------------DEEDDDFDEEEAKEK-APIR--
-----ITPA-KNAQTSN-----QNLKG---S-KP-----------RSKCQESVRNRK---
--LVLKHRKKPSSVDDIKANKYRK----R-------WYCPKVEAI--------REN----
------L---SYC-----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--LMDT-DISLL----
--RPQ-NY---IFGC-L--EANK-DYHFKVDNDEN----EHKLSLRM---VS-LGA--GR
KDGFY--TVEAEVMNYEGS-PIKVI-LATLKMHVQSMVY-LGGFEITLP-V--ALH--QC
VSGPGHMS-TQHLI--------G-MKEDTKQDMK-RRE--IWK-V---------ICPWKW
-VHFHKKKIKLLANENHDADE---------------------------------------
---------------------------------------EEEEDFDEGKTEEK-ALVM--
-KFIQDTP--KNAQKSN-----QNKKDSELS-RL-----------RPKGQES--FKNR--
GNKPLKTPKGPSFVEDIKSKNASKYR-KS-------WFS---------------------
---------------SQSFAWFSVYMYVWNI---MIG---HSSSCG--Q-----------
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQ-NY---LFSCEL--KANK-DYHFKVDNDEN----EHQLSLRM---VS-LGA--GA
KDELH--IVETEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-K-
GSGPVHIS-GQHLV--------A-VEEDAESEDE-EEEDVKRL-STS----GKRSAPGSG
-KKVKLAADE--DDEEEEEDDD---------D----------------------------
----------------------------------EDDED-DDDFDEKET-EE-KAPVK--
-KSVGDSPA-KNAQKSN-----HNGKDSKPST-P-----------ISKVKN-PSK--YRN
---TPKTPKGPSSVEDIKAKMQASIE-KG-------GSLPKVEAK--------FIS----
------HV--KNCFR---------------M---TDQ---EAIQDL--WQWNST------
L-----------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------V-EMRTL----
--RPQ-NY---LFSCEL--KANK-GDHFKVDNNEN----EHQLSLRA---IS-LGA--GA
TDEWD--TVEAEAMNYEGS-PITVT-LATLKMSVQPTVS-LGGFEITPP-V--VLQL-KC
GSGPVHIS-GHHL V--------A-VEEDAESEDE-EKEDVKLL-SIS----GKQFAPGGG
-SKLPQKKVKLATDEDDDGDD---------------------------------------
--------------------------------------------FDDEETEE-K------
-AP------------SN-----QNGKDSKPPSTP-----------RSNGQESFKK--QQK
---SPETPKGPSSV EDIKAKVQASIE-KG-------SSIPKVEAK--------LIS----
------YM--------------------------TDQ---EVIQDI--WQ----------
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MGD--SMDM-DMTPL----
--RPQ-NY---LFGCEL--KADK-DDHFKVDNDEN----EHQLSLRM---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVEPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHL V--------A-VEEDEESEDE-EEEDVKLL-SIS----GKQSV----
----PQKKVKLAADEDDNDDDD---------D----------------------------
----------------------------------DEDDDDDEDDHEEEAE----------
-----------EKAPSN-----QNGKDSKPSSTP-----------RSKGQESFKK--QER
---TPKTPKGP TSIEKV-----------------------GCLPK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRNL------
N--------------------------------------NLLKIFRLISFL---------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMNM-DMSPL----
--RPQN-Y---LFGCEL--KADK-DYHFKVDNDEN----EHQLSLGM---VS-LGA--GA
KDELH--IVEAQAMNYEGS-PIKVT-LATLKMSVQPMVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHL V--------A-VEEDAESEDE-EEEDVKLL-SMS----GKRSAPGGG
-SKVPQKKVKLAADEDDEDDDDE-------D-----------------------------
---------------------------------DD---DEDDDDEDDEETEEK-APVK--
-KSIRDTPA-KNAQKSN-----QNGKDSKLSSTP-----------RSKRQESFKR--QEK
---TPKTPKGPSSV EDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFQ---------------I---TDQ---ESL-----------------
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--LLDM-DMSPL----
--RPQ-NY---LFGCEL--K---------VDNDEN----EHQLSSRT---VS-LGA--GA
KDELH--IVEAEAMNYKGS-PIKVT-LATLKMSVQPTVS-LGGFDITPP-V--VLRL-KC
GSGLVHIS-GQHL V--------A-VEKDAESEDE-EEEDVKLL-SVS----GKRSAPGGG
-SKVPQKKVKLAADEDVHDEE---------------------------------------
----------------------------------DDDDDEDDDDFDDEESEE-KAPVK--
-KSIRDIPA-KNAQKSN-----QNGKDSKPT-----------------------------
----TPRSKGPSSV EDIKAKMQASIE-EG-------DSLPKVEAK--------FVN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WHWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MY----------KTRSQR
SNSALEPWCDSVLRGC---SLEQHSFISIRLLSHLSACCHLIED--SMDM-DMSPL----
--RPQN-Y---LFGCEL--KANK-DDHFKVDNDEN----EHQLSFRI---IS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSEPVHIS-GQHL V--------A-VEEDAESEDE-EEEDIKLL-SIS----GKRSALGGG
-SKVSQKKAKLAADEEDDDDE---------------------------------------
------------------------------------DDDDDDDDFDDEEAEEK-APVK--
-KSIQDTPA-KNAQKSN-----QNGKDSKPSSTS-----------RSKGQESFKN--QEK
---TPKTPKGPN----IKAKMQASIE-KG-------GCLPKVEAK--------FIN----
------YV--KNCFW---------------M---TDQ---EAIQDL--WQWRNLN-----
---------------------------------------NLSKIFCLISFL---------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDMDSIAPL----
--RPQ-NF---LFGCEL--KADKREYSFKVEDDEN----EHQLSLRT---VS-VGA--SA
KDELH--VVEAEGINYEGK-TIKIT-LASLKPSVQPTVS-LGGFEITPP-V--ILRL-KS
GSGPVYVS-GQHLV--------A-LEDLESTDDE-DEE-HDVPSPKN----AKRTASDAA
-SKVPRKKTRLEEEDEADSDEDDDDDDDDE-EE---------------------------
---------------------------------------DDEDEDEEDET-----PVK--
-KTDLPTKP-KAAQKLN-----HNGKASELP-TP-----------LKTPKTPEQKGKQDT
KPQTPKTPKTPLSFDEIKAKMQTSLE-KG-------TVLPKVEVK--------FAN----
------YV--KNCFR---------------T---ENQ---KVIQDL--FKWRQSLKDS--
---------K--------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------KCVS-------PTHG--GFREDGHEHP----
--EAP-DY---LFSCEL--KADR-DYHFKVDNDEN----EHQLSLRM---VS-LGA--GA
KDELC--IVEAEAMNYEGS-PIKVT-LATLKMSIQPIVS-LGGFEIIPP-V--VLQL-KC
GSGPVHIS-GQLVLTRTDQDLVA-VEEDAQSEDK-EKDDM--------------KLVFCG
-SKIPQKKVKLAADEDEEG-----------------------------------------
---------------------------------------DDDDDDFDEEVKEK-APVK--
-K-------------SV-----MEKTQNCQH-QD------------QKVRNPSKKQE---
--KTPKTLEGPSSAEDIKGKMQANIV-RG-------GSLPKVEAK--------FIN----
------YV--MNCFQ---------------M---TDQ---EAIQDL--W-----------
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MKD--SMDM-DMSPL----
--RPQ-NY---LFGCEL--KADK-DYNFKVDNDEN----EHQLSLRM---VS-VGA--GA
KDGLH--IVEAEAMNYEGS-PIKVT-LATLKMSVQQTVSLGGL QNY--------------
------------------------------------TTCGQLL-GMS----GKRSAPRGG
-NKVPQKKVKLDEDD---------------------------------------------
--------------------------------------EDDDDDFDEEETEE-KVPVK--
-KSVRDTPV-KNAQKSN-----QNGKDLKPS-TP-----------RSKGQESFKK--QEK
---TPKTPKGPSSV EDIKAKKQTSIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFQ---------------M---TDQ---EAIQDL--WQWRKPL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--KPQN-Y---LFSCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHLV--------A-VEEDAESEDE-EEDDVKLL-SIS----RKRSAPGSG
-SKVPQKKVKLADEDDDDDD----------------------------------------
---------------------------------EDDDEEDDDDDFDYEEMEEK-APVK--
-KSVRETPA-KNAQKSN-----QNGKDSKPSTPK----------S--KGQESFKK--QEK
---TPKTPKGPSSVEDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--AMDM-DMSPL----
--RPR-NY---LFGCEL--KADK-DDHFKVDNDEN----KHQLSLRT---VS-LGA--GA
KDELH--IVEAQAMNYEGS-PTKVT-LATLKMSVQPMVS-PGGFEI---------TP-PC
GSGPVHIS-GQHLV--------A-VEEDAR-EDE-EEGDVKLL-SIS----GKRSAPGGG
-SKVPQKKVKLAADEDDDDDDE---------D----------------------------
--------------------------------------DDDDDDFDDAETKE---KV---
---------------------------LKTIVNN-----------KIKRTRILQKT-GKK
---TPKTPKGPSSVEDVKANI---------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SVDM-DMSLL----
--RPR-NY---PFSCEL--KADK-DDHFKVDNDEN----EHQL--------S-LGA--GA
KDELH--NVEAEAMNYEGS-PIKVT-PAALKMSVQPTVS-LGGFEIPPP-V--VLRL-KC
GSGPVHIG-GQHL V--------A-VEEDAESEDE-EEEEVKLL-SIS----GKWSAPGG-
-SKVPQKKAKLAADEDDDDEDD---------D----------------------------
--------------------------------------NDD-F-YEEILQPK-MDKK---
---SNQNGK-DS---------------KPS-STP-----------RSKGQESFKK--QEK
---NPKTPKGPSSV EDIKAKMQASIE-KG-------GSLPRVEAK--------FIN----
------YV--KNCFC---------------T---TEQ---EAIQDL--WHLNNL------
L-----------------------------------------KIFSLISFL---------
------------------------------------------------------------
-------------------

MWYIYTMEYYSAIKNNDFMKFIGKWMELENIILSE FLAQ-PLRKQLYQVPVIKR--FLAS
AMVSEFSVRSHNETSSYLADPTIPLS-----SEIILFLLLSRTEASTPCSSSMVSHGLDT
WDKGSTEESIEVTLAVTHSIGDIEPEEATFSSRQEPQKKCPYCSSPFPSLFLPFEQKDRV
PPSETSHKRNINKRQLTPITNTVASPSNLGKEKDPESGNRLRDSFCSSCW-RTSMKTKWL
L-------------CYM-WGTGFGPCPYCIYIGGNT------------------SQPH--
TFLLSK--------PHIKPDLKPWYQ-----QSF-----IIDKD--SMDM-DMSPL----
--RPQ -SY---LFGCEL--KADK-DYHFKVDNDEN----EHRLSLGT---FS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LWGFAITPP-E--VLKL-KC
GSGPVHIS-GQHLV--------A-VEEDAESEDE-DEEDVKLL-GMS----GKRSAPRGG
-NKVPQKKVKLDEDDEDDKDDDDDD-----------------------------------
-------------------------------------DDH--DNFDEEETEEK-VPVK--
-KSVRDIPA-KNAQKSN-----QNGKGLNPS-TP-----------RA-------------
----------PVHLFSARALTQSDET-SS-------QRTCRPSSPISESGIQFLIE----
------TI--EKPGETHSMLLFGICYVPWHL---KKG---NISNTQ--WAQQQVFPPTLP
ESFPYTGGQTLA-GPGASPSIVAQQDHPLLHMQLGVMGQSMYSLGVVEALVG--------
--WYCCSYRVASPFSSFNPFSNSSNRDLSYFRLSRSKTQLTTNAGKDVDVEKEEHSFIAG
GISNWYDLSGNQSGDSSEN

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQ-NY---LFGCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTV STILNF----------------
---------GFHVG--------AAVEEDAESEDE-DEEDVKLL-GMS----GKRSAPGGG
-NKVPQKKVKLDEE--DEDDDE---------D----------------------------
---------------------------------DEDDEDDDDDDFDEEETEE-KVPVK--
-KSVRDTPA-KNAQKSN-----QNGKDLKPS-TP-----------RSKGQESFKK--QEK
---TPKTPKGPSSV EDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RLQ-NY---LFGCEL--KADK-DYHFKVDNDEN----EYQLSLRT---VS-LGA--RA
KDELH--IVEAEAMNYEGS-PIKVT-LASLKMSVQPMVS-LGGFEITPP-V--VLKL-KC
GSGPVHIS-GQQLV--------V-VEEDAESEDE-EEEDVKLL-S--------------G
-NKVPQKKIKFAADEDDDEDE---------------------------------------
----------------------------------DDDEDDDDDDFDDDEAEE-KAPVK--
-KSIQDIPA-KNTQKSN-----QKGKDSKPST-P-----------RSKGQEAFKK--QEK
---TPKTPKGPSSVEDIKAKMQASIE-KA-------H-----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------VED--LMDM-DMSPL----
--RPQ-NY---LFCCEL--KANK-DYHFKVDNNQN----EHQLSLRT---VS-LGA--GA
KDELH--IVE-EAMNYEGS-PIKET-LATLKMSVQPTVS-LGGFEITAP-V--VVRL-KC
GSGSVHIS-GQH LE-------------DAESDEE-EEEDVKLL-SIS----GKRSAPGSG
-SKVPQKEVKLAADDDDDN-----------------------------------------
-------------------------------------------DDDDEEAEE-KAPVK--
-KSIRDTPA-KNAQKSN-----QNGKDSKP-STP-----------RSKGQESSPK--QEK
---TPKTPKGRSSV EDIKAKMQASIE-KS-------GSLPKVETN--------ILI----
------K-----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--LMDM-DMRPL----
--RSQ-NY---LFGCEL--KADK-DYHFTVDNDEN----EHQLSLRT---AS-LGA--GA
KDELL--IVEAEAMDYEGS-PIKVT-LATLKMSVQP----------------------T C
GSGPMHIS-GQHLV--------A-VEEHAESDDE-EEEDVKLL-SIS----RKRSAPRSG
-IKLAADE----DDDDDDDDND---------D----------------------------
---------------------------------EDDDEDDIVDDFDDEKAEE-KTPVK--
-KSIRDTPA-KNAQKSN-----QNGKDSKPS-TP-----------RSKGQEYFKK--QEK
---TPKTPKGPSSV EDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFW---------------M---TDQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------MP-------SPH------RRSIGHG----
--HPQ-NY---LFSCEL--KADK-DL--WVDDDEN----EHELSLRT---VS-LAA--GA
KDESH--IAEAEAMNYEDS-PITVT-LATLKMSVQPAVS-LGGFAVKSP-A---------
------------------------------------------------------SAPAGG
-DKVPHKEVKLAADKDDQD-----------------------------------------
---------------------------------------TEDKAVKKS--------IQ--
------------------------DTPAKNA-QK-----------NQNVKDHREKQE---
--KTPKTLKG---IKDIKRKAQASIE-KG-------GSLPKVEAK--------LIH----
------YM--KNCFQ---------------M---TDQ---D--QDL--WQWKKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQN-Y---LFGCEL--KADK-DYHFKVDNDEN----KHRLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHL V--------A-VEEDAESEDE-EDEDVKLL-SIS----GKRSAPGGG
-GKVPQKKVKLNDD----------------------------------------------
------------------------------------DEDDDDDDFDDEETEEK-APVK--
-KSVRDTSA-KNAQKSN-----QNGKDSKPSTPR----------S--KSQESIKK--QEK
---TPKTPKGPSSV EDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQNL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------LEQWVP-----VSI-----R-----------LLSHL----
--TPQ-SY---LFSCEL--KADK-DYLFKVDNDEN----EHQLSLRT---V---------
----------REAMNYEGS-PIKVT-QAALKMSVQPTAS-LGGFETTPP-V--VLQV-KC
GSGPGHIS-EQHLE--------A-VEEDAESEDE-EEEDHIWK-A---------ISPGSG
-SKGPQKKVELADEDNDDD-DEDED-----------------------------------
-------------------------------------DDD--DDFDDEETEER-APVK--
-KSVRETPA-KNAQKSN-----QNGKTQNHQ-HP-----------NQK------------
-EKTPETPKGPSSIEDSKAKMQ------------------------------A-------
------SI--EKA-----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--KPQ-NY---LFGCEL--KANK-DYHFKVDNDEN----E------T---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQLTVS---------------------
------------------------IGEE-------EEED VKLL-SIS----G--------
-NKVPQKKVKLDEDD---------------------------------------------
------------------------------------------DDFDDEETEGK-APNG--
-KDSKPS-------TPR-----SEG-----------------------------------
---QESFKKQEDSV EDIKAKMQASIE-KC-------GSLPRVEAK--------FIS----
------YV--KNSFW---------------M---TDQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQN-Y---LFGCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHL V--------A-VEEDAESEDE-EEEDVKLL-SIS----GKRSAPGGG
-SKVPQKKVKLAADEDDDDDD---------ED----------------------------
---------------------------------D-DDEDDDDDDFDDEEAEEK-APVK--
-KSIRDTPA-KNAQKSN-----QNGKDSKPSSTP-----------RSKGQESFKK--QEK
---TPKTPKGPSSV EDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQ-NY---LFGCEL--KADK-DDHFKVDNDKN----KHQLSLRT---VS-LGA--GA
KDELH--VVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LG--------V--VLRL-KC
GSGLVHIS-GQHLV--------A-VEEDAESEDE-EEEDVKHL-SVS----GKRSATGGG
-SKVPQKKVKLAADEDDDDDD---------------------------------------
-------------------------------------EDDD-DDFDDEEAEE-KAPVK--
-KSILDTP--------------------AK-NAQ--------------------------
-----------NSVEDVKAKMQASVE-KA-------H-----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQ-NY---LFSCEL--K--------------------HQLSLRT---VS-LGA--GA
KNELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFETTPP-V--VLRL-KC
GSGPVHIS-GQHL V--------A-VEEDSESEDE-EEEDMKLL-SIS----GKRSAPGGG
-SKVPQKKVKLAADEDDDDD----------------------------------------
-----------------------------------EDDDDD-DDFDDEEAEE-KAPSN--
-QNGKDSK--------------------TI-ITP-----------RSKGQESFKK--QEK
---TPKTPKGPSSV EDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRNL------
N--------------------------------------NLLKIFHLILFL---------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MGD--SMDM-DMTPL----
--RPQ-NY---LFGCEL--KADK-DDHFKVDNDEN----EHQLSLRM---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVEPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHLV--------A-VEEDEESEDE-EEEDVKLL-SIS----GKQSV----
----PQKKVKLAADEDDNDDDD---------D----------------------------
-----------------------------------EDDDDDEDDDEEEAE----------
-----------EKAPSN-----QNGKDSKPSSTP-----------RSKGQESFKK--QER
---TPKTPKGPTSIEKV-----------------------GCVPK--------FIN----
------YV--KNCFQ---------------M---TDQ---EAIQDL--WQWRNL------
N--------------------------------------NLLKFFRLISFL---------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------LRK--LEDF-PYGPV----
--RPYPRL---LSRCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHLV--------A-VEEDAESEDE-EEDDVKLL-SIS----GKRSAPGSG
-SKVPQKKVKLADEDDDDDDED---------E----------------------------
---------------------------------D-DDEDDDDDDFDDEETEEK-APVK--
-KCVLSTVD-NCLQKGW-----QRGSWNKKSLRP-----------CPKGQESFKK--QEK
---TPKTPKGPSSVEDIKAKMQASIE-KT-------SL-KPALPV--------VHCIG--
----INYIKTVLKRN---------------I---TYE---QAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------CEL--KANK-DDHFKVDNDEN----EHQLSLRI---VS-LGA--SA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHL V--------A-VEEDAESEDE-EEEDIKLL-SIS----GKRSALGGG
-SKVPQKKVKLAADEEDDDDED---------D----------------------------
--------------------------------------DDD-DDSDDEEAAE-KAP----
------NGK-DS---------------KPS-STS-----------RSKGQESFKN--QEK
---TPKTPNGP----NIKAKMQASIE-KG-------GCLPKVEAK--------FIN----
------YV--KNCFW---------------M---TDQ---EAIQDL--WQWRKS------
L-----------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--LMDM-NMSPL----
--RPQN-Y---LFGCEL--KADK-NYQSKVDNDEN----EHQLSLTM---VS-LGA--GA
EDELH--VVEAEAMNYKGS-PIKVT-LATLKMSVQPTVS-LGGFKVTPP-V--DLRL-KC
GSGPVHIS-GQHL V--------A-VEEDAESEDE-EEEDVKLL-TVS----GKRSAPGGG
-SKVPQKKVKLAADEDDDEDDDD-------------------------------------
------------------------------------DDEDDDDDSEDEEAKEK-GPVK--
-KSVRDSPA-KNAQKSN-----QNGKDSKPSSTP-----------KSKGQEFFKK--QEK
---TPKTPKGPSSV EDIKAKMQASIE-KG-------GSLRRVGAK--------FIN----
------YV--KNCFW---------------M---IDQ---EAIQDL--WQWRNLN-----
---------------------------------------NLLKIFLLIVWVK-------E
KG-----QD-GGR-----------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--QPQ-NY---LFGCKL--KADK-DDHFKVDNDEN----EHQLSLRT---IS-LGA--GA
KDELH--IIEAEAMNYEGS-PIKVT-LATLKMSVQ---------------------L-KC
GSGPVHIS-GQHL V--------A-VEEDAESEDE-KDEDVKLL-SMS----GKQSAPEGG
-SKVVQKKVKLEEDDD--------------------------------------------
--------------------------------------DDDDDDFDDEEVEE-KVPVK--
-KSIQDTPA-KNAQKSN-----QNRKDSKPA-TP-----------RSKGQESFKK--QQK
---TSKTPKGPSSV EDIKAKMQASIE-KG-------GSLPKVEAK--------F-N----
------CV--KNCLR---------------M---TDQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--LMDR-DMSPL----
--RPQ-NY---LFSCEL--KADK-DDHFKVDNDEN----EHQLSLRT---VS-LGP--GA
KDELQ--IIEAEAMNYEVT-LATL---------KIF--------EITHP-V--VLQL-KC
GSGPVYMS-GQHLV--------A-VVEDAESEDE-EGEDVKLL-SIS----GKQSATGGG
-RKIPQKKVKLAADEDDDD-----------------------------------------
---------------------------------------EDDDDFDDEGSEEK-APVK--
-QSIRDTPA-KKGQKSN-----QNGKDSKPSSTP-----------RSKGQESFKKKKQEK
---TPKTPKGPSSVEDIRAKMEASIE-KV-------H-----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------Y---SFSSEL--KADK-DYHFKVDNDEN----EHQL-LRK---VS-LRA--GA
KIELH--IVEAEAMNYEGS-PIKVT-LA-LKMSVESTVS-LGGFEIPPP-V--VLQL-KY
VSGPVHTN-GQHLA--------P-VEEDAESEDE-EEEVVKLL-SIS----G------NS
-SKFPQKKVKLTDEDDDDD-----------------------------------------
----------------------------------DDDDDDDDDDFEDEETEEK-VPVR--
-KSIRETPD-KNAQKSN-----QNGKDSKPS-TP-----------KPRDQ-------EEK
---TPKTPEGPSSIEDIKAKMQASVE--------------KVEAK--------FIK----
------YM--KNCFW---------------M---TDQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMHM-DMSPL----
--RPQ-NY---LFSCEL--KAHK-DYHFKVDNDKN----EHQFL----------GA--GA
KDELY--IVEAETMNYEGS-PTKVT-LATLKMSVQPTVS-LGGFEITPP-M--VLRL-KC
GSGPVHTS-GQHL V--------A-VEEDAESDEEEEEEDVKLL-SIS----GKRSAPGNS
-IKLAA------------------------------------------------------
----------------------------------DEDDDDDDDDFDDKEAEEK-APVK--
-KSMLD------T------------------------------------P--------EK
---TPKTSKGPSSV EDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---E---------WRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SVDM-DMSLL----
--RPR-NY---LFSCEL--KADK-DDHFKVDNDEN----EHQLSL-----------GAGA
KDELH--IVEAEAMNYEGS-PIKVT-PAALKMSVQPTVS-LGGFEIPPP-V--VLRL-KC
GSGPVHIG-GQHL V--------A-VEEDAESEDE-EEEEVKLL-SIS----GKWSAPG-G
-SKVPQKKAKLAADEDDDDE----------------------------------------
-------------------------------------------DFYEEIL----------
-------QP-KMDKKSN-----QNGKDSKPSSTP-----------RSKGQESFKK--QEK
---NPKTPKGPSSVEDIKY------R-KG-------GSLPRVEAK--------FIN----
------YVH-KNCFC---------------T---TEQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------F---FAGCEL--KADK-EYKFKVDDEEN----EHQLSLRT---VS-LGA--GA
KDELH--VVEAEALDYEGN-PIKVV-LASLKMSVQPTVS-LGGFEITPP-V--TLRL-KC
GSGPVYVS-GQHLV--------A-LEEEPESEDE-EED-TKIV-NAS----TKRPASGGG
-SKTPQKKAKLSEDDEDDDE-----D-------D--DE----------------------
--------------------------------------DDLDDDEEEIKT-----PMK--
-KPVREPSG-KNMQKAK-----QNGKDSKPS-TP-----------ASKTKTPDSK-K--D
KSLTPKTPKVPLSLEEIKAKMQASID-KG-------SSLPKLEPK--------FAN----
------YV--KNCFR---------------T---EDQ---KVIQAL--WQWRQTL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------GCEL--KAEK-EYQFKVDDEEN----EHQLSLRT---VT-LGA--GA
KDELH--VVEAEALDYEGN-PVKVV-LASLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVYVS-GQHLV--------A-LEEEPESEDE-EED-TKIV-NAS----TKRPASGGG
-AKTPQKKAKLSEDDEDDDEDEDDDD-------D--DE----------------------
--------------------------------------DDLDDDEEEVKT-----PMK--
-KPAREPAG-KNMQKAK-----QNGKDSKPS-TP-----------ASKTKTPDSK-K--D
KSLTPKTPKVPLSLEEIKAKMQASVD-KG-------CSLPKLEPK--------FAN----
------YV--KNCFR---------------T---EDQ---KVIQAL--WQWRQSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQN-Y---LFGCEL--KADK-DYHFKVDNDEN----EHQLSLRM---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEIKPP-V--VLRL-KC
GSGPVHIS-GQHL V--------A-VEEDAESEDE-EEEDVKLL-SMS----GKRSAPGGG
-SKVPQKKVKLAADEDDDDE----------------------------------------
---------------------------------------DDDDDFDAEETEEK-VPVK--
-KSIRDTPA-KNAQKSN-----QNGKDSKPSSTP-----------RSKGQESFKK--QEK
---TPKTPKGPSSV EDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRNLN-----
---------------------------------------NLLKIFRLISFL---------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQN-Y---LFGCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHL V--------A-VEEDAESEDE-EEEDVKLL-SMS----GKRSAPGGG
-SKVPQKKVKLAADEDDDDDEDD-------DD----------------------------
---------------------------------D-DDEDDDDDDFDDEETEEK-VPVK--
-KSIRDTPA-KNAQKSN-----QNGKDSKPSSTP-----------RSKGQESFKK--QEK
---TPKTPKGPSSV EDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQ-NY---LFGCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
-----------EAMNYEGS-PIKVT-LAILKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHLV--------V-VEEDAESEDE-EEED--VL-SMS----GKRSAPGGG
-NKVPQKKVKLAADEDDDEDED---------D----------------------------
---------------------------------DEDEDDDDDDDFDDDEAEE-KAPVK--
-KSIRDIPA-KNAQKSN-----QNGKDSKPST-P-----------RSKGQEAFKK--QEK
---TPKTPKGPSSVEDIKAKMQASIE-KA-------H-----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQ-NY---LFGCEL--KADK-DYHFKVDNDEN----EYQLSLRT---VS-LGA--GA
KDELH--IVEVEAMNYEG-------------------IS-LGGFEITPP-V--VLRL-KC
GSGPVHI------I--------V-VEEDAESEDE-EDEDVKLL-SIS----GKRSTPGGG
-SKVPQKKIKLAADEEDD------------------------------------------
-----------------------------------DDDEDDDDDFDDEETEE-KAPVK--
-KSVRDTPA-KNAQKSN-----QNGKDSK-PSTP-----------RSKGQESIKK--QEK
---TPKTPKGPSSVEDIKAKMQASIE-KG-------ASLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--YLNSLL------
------------------------------------------KVFCLISFL---------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQN-Y---LFGCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHL V--------A-VEEDAESDDE-EEEDVKLL-SIS----GKRSAPGSG
-SKVPQ------------------------------------------------------
---------------------------------------DDDDDFDDEETEEK-APVK--
-KSIRDTPA-KNAQKSN-----QNGKDSKPSTPR----------S--KGQESFKK--QEK
---TPKTPKGPSSV EDIKAKMQASIE-KG-------GSLPKVEAK--------FVN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQN-Y---LFGCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHL V--------A-VEEDAESEDE-EEEDVKLL-SMS----GKRSAPGGG
-SKVPQKKVKLAADEDDDDEDDD-------------------------------------
---------------------------------D-DDEDDDDDDFDDEETEEK-VPVK--
-KSIRDTPA-KNAQKSN-----QNGKDSKPSSTP-----------RSKGQESFKK--QEK
---TPKTPKGPSSV EDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMG----IPL----
--RPQ-NY---LFGCEL--KAYK-DYHFKVDNDEN----EHQLFLRT---VS-LGA--GA
KDELD--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGDSEITPP-V--ISRL-KC
GSGPVHIS-GQHL V--------A-VEEDAESEDE-EEEDVRLL-SIS----GKRSATGGG
-SKVPQKQVKLAADEDDGDDKD---------D----------------------------
--------------------------------------DGD-DDFDDEETEG-KAPVK--
-KSIQDTPA-KK---------------C--------------------------T--KEK
---APKTPKGPSSV EDIKAKMQANVE-KG-------LSFPKVEAK--------FFN----
------YV--KNCFR---------------R---IYQ---EAIQDL--WQWRKS------
L-----------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQ-NY---LFGCEL--KADR-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHL V--------A-VEEDAESEEE-EEEEVKLL-SIS----GKRSAPGSG
-SKVPQKKVKLAADEDEDDDDD---------D----------------------------
----------------------------------DDDDEEE---YC--------------
----------------------------VE-IYF-----------FFQGQESFKK--QEK
---TPKTPKGPSSV EDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EVTELS--GDMTK-------
-----------------------------------------SRIFIVIYYGCLVSLGIG-
--FF--------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--LMDR-DMSPL----
--RPQ-NY---LFSCEL--KADK-DDHFKVDNDEN----EHQLSLRT---VS-LGP--GA
KDELQ--IIEAEAMNYEVT-LATL---------KIF--------EITHP-V--VLRL-KC
GSGPVYIS-GQHLV--------A-VVEDAESEDE-EEEDVKLL-SIS----GKQSATGGG
-RKIPQKKVKLAADEDDDDEDD---------D----------------------------
--------------------------------------DEEDDDFDDEESEEK-APVK--
-QSICDTPA-KKGQKSN-----QNGE---------------------------------K
---TPKTPKGPSSVEDIRAKMEASIE-KV-------H-----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQN-Y---LFGCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHL V--------A-VEEDAESEDE-EEEDVKLL-SVS----GKRSAPGGG
-SKFPQKKVKLAADEDDDNDDEE-------------------------------------
-----------------------------------DD--DDDDDFDDEEAEEK-APVK--
-KSIRDTPA-KNAQKSN-----QNGKDSKPS-TP-----------RSKGQESFKK--QEK
---TPKTPKGPSSV EDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRNLN-----
---------------------------------------NLLKIFRLISFLLTVDIWLSF
L-----------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--LMDM-DMSSL----
--RLQ-NY---LFKL----KANK-DYHFKVDNGKN----EHQLPLRM---VS-LGA--GT
KDELH--IVEA-DMNYEGS-PIKLM-MATLKMSIQPM-V-LGGMKIKPV-E--FC-L-KC
SSRTVHIN-GWYLL--------A-VEEDAEKEGE-EEEDVKLL-RI---------P-T--
------KEMQPAQEWH--HPHGQLTQQDDTTKRN-TDF----------------------
--------------------------------HATDNNRSRQDDEDEDEDEDV-SPVK--
-KIYQRNPA-KNAQKSN-----QKGKDSKPS-IP-----------KSKCQELFKQ-----
E-KAPKTLKGSSSVEDFKAKMQARIE-KG-------GSLPKVEAK--------FIN----
------YE--KNCFM---------------N---D-Q---EAIQDL--WQWGKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MEDS--AMDMESMGPL----
--RPQ-TF---LFGCEL--KAEK-EYQFKVDDEEN----EHQLSLRT---VT-LGA--GA
KDELH--VVEAEALDYEGN-PTKVV-LASLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVYVS-GQHL V--------A-LEEEPESEDE-EED-TKIG-NAS----TKRPASGGG
-AKTPQKKPKLSEDDEDDDEDEDDDE-------D--DE----------------------
--------------------------------------DDLDDDEEEIKT-----PMK--
-KPAREPAG-KNMQKAK-----QNGKDSKPS-TP-----------ASKTKTPDSK-K--D
KSLTPKTPKVPLSL EEIKAKMQASVD-KG-------CSLPKLEPK--------FAN----
------YV--KNCFR---------------T---EDQ---KVIQAL--WQWRQTL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--LMDM-DMSPL----
--RPQ-NY---LFNDY-----------LKVDNDED----EHQLSLRI---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSIQPTVS-LGGFEITLP-----------
-------V-GQHLI--------A-VEEDARKD-E-EEEGVKLL-TIS----GERSAPGGG
-SKIPQKKVKLAADEDDDYED---------------------------------------
---------------------------------DDDEDEDDDDDFDDKDTKEK-AP----
----------------------------------------------------------EK
---APKTPKGPSSV EDVKANMQASIE-KG-------GSLPQVEAK--------FIN----
------YV--KNCFW---------------M---TDQ---EAIQDL--------------
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMVM-DMSLL----
--RPQ-NY---LFGCEL--KADK-DYHFKNEH---------QFSLRM---VS-LGV--GV
KDELH--TVEAEAMNYEVS-PLKVI-LATLKMSVQPTVS-LGGFETTPP-V--VFQL-RC
GSGPVHIS-GQHLV--------A-AEEDAESEDE-DEEDVKRL-SMS----GKQSALGGG
-NKCLA------------------------------------------------------
--------------------------------------VGEDDDFDDEETEKK-VPLK--
-KSVQVIPA-KSAQKSN-----QNG------------------------QEFFKK--QEK
---TLKTPKGPSSVEEIKA-----------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQN-Y---LFGCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VFIV-SS
SENPMIMS-DNFIL--------A-VEEDAESEDE-EEEDVKLL-SIS----GKRSAPGGG
-SKVPQKKVKLAAEEEKDGK--G-------------------------------------
---------------------------------MAQDRFDDDDDFDDEETEEK-APVK--
-KSIRDTPA-KNAQKSN-----QNGKDSKPSTP------------RSKGQESFKK--QEK
---TPKTPKGPTSVEDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPLKREP
LRPAQ-NY---LFGCEL--KADK-DYHFKVDDDEN----EHQLSLRT---VSFLGA--GA
KDELH--IVEAEAMN------YGDS-------PIKPTVS-LGGFEMTPL-V--VLRL-KC
GSGPVHIS-GQHS V--------A-VEEDAESEDE-EEEDVKLL-SMS----GKWSQVST-
------EKVKLAADE---------------------------------------------
---------------------------------------DDDDDFDDEETEEK-VPVK--
-KSICDPPA-KNAQK-------------------------------SKGQESFKK--QEK
---TPKTPKGPSSV EDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------I---TDQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------VED--SMDM-NMSPL----
--RPQ-NY---LFGCEL--KADK-DYHFKVANDEN----KHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEG--------SPIKV--TLPMVF-LRGFEITPP-V--VL H----
--GQ-------HLV--------A-VEEDGCSQEM-----KRKR-IIS----GKHSAPGSG
-SRIPQRKSKTYDDEDEDDHDD--------------------------------------
------------------------------------DENDDKDDFDYEEAEEK-SK----
------------------------------------------------GQESFKK--QEK
---TPKTLKGPSSV EDTKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCF----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQ-NY---LLGCEL--KANK-DHHFKVDIHEN----EHQLSLRT---VSS-GA--AA
KD-----------ESPIKV-TLATLK-----MSVQPMIS-LSVFEIIPP-V--VLQL-KC
GSEPVHIS-GQHLV--------A-VEEDAEPEDE--EEDVKFL-SIS----GRRSLPE--
------KKVKPAA-----------------------------------------------
--------------------------------------NEDDDDFDDEETEGK-APVK--
-KSTQDTPAKKNAQKSN-----QNGKDSIPS-IP-----------RSKGQESFKK--QEK
---N--------SVE NTKAKMQASIE-KG-------GSLPKVGAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--W-----------
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQN-Y---LFGCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHL V--------A-VEEDAESEDE-EEEDVKLL-SIS----GKRSAPGGG
-SKVPQXXXXXXXXXDDDDE--E-------DD----------------------------
---------------------------------DDDEDDDDDDEFDDEDTEEK-APVK--
-KSVRDTPA-KNAQKSN-----QNGKDSKPSTPR----------S--KGQESFKK--QEK
---TPKTPKGPSSV EDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------M-DTSPL----
--RPQ-NY---LFGCEL--KADR-DYHLKVDNDEN----EHQ-L----------SL--RT
--------------VSLGS-PIKVT-LATLKMSVEPTVS-LGGFEITPP-M--VLRL-KC
GSGPVHIS-GQHLV--------A-VEEDAESDED--EEDVKLL-SMP----GKRSAPGGG
-NKVPEKKVKLDDDDEEEE-----------------------------------------
----------------------------------EED-EEDDDDFDDEEAEEK-VPVK--
-KSSPS----KNR------------------------------------K--------KK
---NPKTPKGPSSVDNIKAKIQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--LMDV-DMSSL----
--RPQ-NY---LFGCEL--KADK-DYHFKVDNDEN----E------T---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVI-LATLKMSVQPTVS-LGGFEITPP-V--VLML-KC
GSGPVHIS-GQHL V--------A-VEEDAESEDE-EEEDVKLL-SIS----GKRSALGGS
-SKLPQKKVKLAADEDDD------------------------------------------
-----------------------------------DDEEDD-DDFNDEEAEE-KVPDK--
-NL----S--------------------KN-RKK-----------T-----------P--
-----KTPKGPGSV EDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRKS------
L-----------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQN-Y---LFGCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITSP-V--VLRL-KC
GSGPVHIS-GQHL V--------A-VEEDAESEEE-EEEDVKLL-SIS----GKRSAPGGG
-SKVPQKKVKLTADEDDEDDEDE-------DE----------------------------
---------------------------------DDDDEDDDDDDFDDEETEEK-APVK--
-KSIRDTPA-KNAQKSN-----QNGKDSKPSTPR----------S--KGQESFKK--QEK
---SPKTPKGSSSV EDIKAKMQASIE-KG-------GSLPKVETK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-GMSLW----
--R--------LFSCEL--KAYK-DYHFKVDNDEN----EHQLSLRI---VR-LRA--GT
KDELH--IIEAEAMNYEGS-PIKVA-LATLKMTVQPMVS-IGGFELIPP-V--VLRG-KC
GSRPVNIS-GQHL V--------V-VEEDAESEDE-EEEDVKLL-SMS----GK-----GG
-NKVPQKKVKLSADEDEDEDED---------D----------------------------
-------------------------------------EDNDDDDFDDNEAEEK-APVK--
-KPP--------------------------------------------------KNRKKK
---TPKTPKGPSSVEDI KGG-----------------SLPKV------------------
----------ENCFQ---------------M---TDQ---EAIQDL--WQWRKFL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MDD--LMDM-YMSPL----
--RPQ-IY---LVSCEL--KADK-DDHLKMDNDEN----EHQLSLIT---VS-LWI--GA
KDELH--IVEAKAMKYKGS-PMEVT-LETLKMSAQPTSL-GG-FEITPF-V-------TC
CSGPVHNG-GYK-----------------------EEEDVKLL-SIS----GKQSNLGSG
-STFPQGEKIGVSENDDE------------DDDDDDDE----------------------
--------------------------------EDDDDDEDDDEHDKEGEAEEK-GPVK--
-SLYEVLQP--RMQT--------RMKDSKPS-TP-----------RSKGPQPFKKQ----
--ETTRKPKRPSPIKDIKVKLRLHVE-KG-------S-----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------VED--SMDL-DMSLL----
--RPQ-NY---LFSCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEATNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRF-KC
GSGPVHIS-GQHLV--------A-VEEDAESEDE-EEEDVKLL-SIS----GKRSTPGGG
-SKIPQKKVKLAAAAADEDD----------------------------------------
---------------------------------------NDEDDDDEEEAEE-NAPVK--
-KSIQDTPA-KNAQKSN-----QNRKDSKPSSTP-----------RSKGQESFKK--QEK
---TPKTPKGPSSVEDIKAKMQASIE-KA-------SRKFRKFSS--------ILIIF--
------------------------------------S---QR-VLV--LQWK--------
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPR-NY---LFSCEL--KADK-DDHFKVDNDEN----EHQLSLRM---VS-LGA--GA
KDELY--IVEAKAMNSEGS-PIKVT-LATLKMSVQPTVS-LGACN PST------------
--------------------------------------LGGRG-GMS----GKQSAPGGG
-SKVPQKKVKLDVDD---------------------------------------------
--------------------------------------EDNDDDFDVEETEEK-VLVK--
-KSICNTPA-KN----------------------------------------------EK
---TPKTPKGPSSVEY IKANVQESIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFQ---------------M---TDQ---ERKSL---------------
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--AMDM-DMSPL----
--RPR-NY---LFGCEL--KADK-DDHFKVDNDKN----KHQLSLRT---VS-LGA--GA
KDELH--IVEAQAMNYEGS-PTKVT-LATLKMSVQPWFP-LGALNV--------FWL-KC
GSGPVRIS-GQHL V--------A-VEEDAR-EDE-EEGDVKLL-SIS----GKRSAPGGG
-SKVPQKKVKLAADEDDDDDED--------------------------------------
----------------------------------------DDDDFDDVETKEK-V-----
----------------------------------------------SKGQESFKKQ-GKK
---TPKTPKGPSSVEDVK KKVVLFPK-WK--------PSSSIML----------------
----------KNCFW---------------M---TDQE---AIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQN-Y---LFGCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDGLH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHL V--------A-VEEDAESEDE-EEEDVKLL-SMS----GKWSAPGGG
-SKFPQKKVKLAADEDDDDE----------------------------------------
-------------------------------------DDDDDDDFDDEETEEK-VPVK--
-KSIRDTPA-KNAQKSN-----QNGKDSKPSSTP-----------RSKGQESFKK--QEK
---TPKTPKGPSSV EDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRNLN-----
---------------------------------------NLLKIFRLISFL---------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--KPQ-NY---LFGCEL--K---------VDNDEN----EHQLSLRM---IS-LGA--GA
KDELH--IVEAEAMHYEGS-PIKVT-LATLKMSVQPTVS-LGGFEIAPP-V--VLRL-RC
GSGPVHIS-GQ HPV--------A-VEEDAESEEE-DEEDDKLL-SMS----GKRSAPGSG
-SRVPQKKE-------EEDEDD---------E----------------------------
----------------------------------DDE-DDD-DDFDDEETEE-KVP----
---------------------------------------------------SFKK--QEK
---THKTPKGPSSV EDIKTKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EATQDL--WQWRKS------
L-----------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------M-DMSPL----
--RPQ-NY---LFSCEL--KADK-DYHFKVDNDEN----GHQLSLRM---VS-LGA--GA
KDELY--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--DLRL-KC
GSGPVHIS-GQHL V--------A-VKEGAESEDE-EEEEVKLL-SIS----GKQSAPGGG
-QKK----VKLAAGAADDDED---------------------------------------
--------------------------------------N-DGDYDDEEA-EE-KAP----
---------------SN-----QNGKDSKPSSTP-----------RSKGQESFKK--QEK
---SPKTPKGSSSV EDIKAKMQASIE-KG-------GSLPKVETK--------FIN----
------YV--KNFFW---------------M---TDQ---EAIQDL--WQWRKS------
L-----------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMEM-DMSPL----
--WPQ-NF---LFGCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAESLNYEGN-PIKVT-LASLKMSVQPTIS-LGGFEITPP-V--VLWF-KC
GSGPVHVS-GQHLV--------A-LEEDAESNDE-VEDDMKLL-NMS----GKRSAPGVG
-SKVPQKKVKLSEKDEED------------------------------------------
------------------------------------DEEDSDDDFEDEESEEKTPPVK--
-KSVCDTVA-KNTQKSN-----QNGKDSK-QSTP-----------KAKGQDSFKK--QDK
---TPKTPKGPTSLEDIKAKMQASIE-KG-------GSLPKVEGK--------FINYFLY
SSLFLHYV--KNCFP---------------I---SDQ---EAIQDL--WLWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SVDM-DMNPL----
--RPP-NY---LFGCEL--KADK-DYHFKVDNDEN----EQQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-SIKVT-LAALKMSVQPTVS-LRGFEITPP-V--VLRL-KC
GSGPVHIS-GQHL V--------A-VEEDAESDDE-KEEDVKLL-STS----GKQSAPGSG
-SKVPQKKVKLAADEDEDEDDE---------D----------------------------
----------------------------------EGDDEDDDNDFDEVET----------
-------------EEKA-----ANGKDSKPP-TP-----------RSKGQESFKK--QEK
---TPKTPKGPNSI EDIKAKMKASTE-KG-------GSLPKVEAK--------FIN----
------YV--KNSPK---------------QNGMKRG---KSQQTL--WKSRRS------
S----------------------------------------IPTFRICILIR--------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DINPW----
--RPR-NY---LFGCEL--QADK-DYHFKVDNDEN----E------T---VS-LGA--DG
KDELH--IVETEAVCYEGS-PIKVT-LATLKMSVQPTIF-LRGFEITPP-V--VLRL-KC
GSGPVHIS-EQHL V--------A-VEED-------AEEDVKLL-SIS----GKWSAPGGG
-SKVPQKKVKLATDEDDDD-----------------------------------------
-----------------------------------NDEDDDNDDFDNEETEEK-APVK--
-KSIRDTPA-KNAQKPN-----QNGKD-------------------------------SK
---PSSTPRSNGSV EDIKAKMQASIE-KG-------GSLPKVEAK--------FIS----
------YM--KNCFR---------------M---TDR---EAIQDL--WQLRNLN-----
---------------------------------------NLLKFFCLTSFL---------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
MLIVNVAWYDSILSGC---SLEQRSFISVRLLSHLSVCRHPTGD--SMHM-DVSPL----
--RPQ-NY---LFGCEL--KADK-DDHFKVDNDEN----EHQLCLRT---AS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSAQPAVS-RGGFEITPP-V--VLRL-KC
GSGPVHVS-GQH LA--------A-VEEDAESEDA-EEKDAKLF-SIS----GKRSAPGGG
-TRVPQKKVKLAVDEDDDD-----------------------------------------
----------------------------------------D-DGFDDEEAEE-KVPSN--
-Q----NGK-DS---------------KPS-STP-----------RSKGQESFKK--QEK
---TPKTPKGPSSV EDIKAKMQASIE-KG-------GSLPKVEAE--------FIN----
------YV--KNCFW---------------L---TDQ---EAIQDL--WQWRKS------
P-----------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--LMDM-VMSPL----
--RPQ-NC---LFDCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEADAMNYAGS-PIKVT-LATLNMSVQPTVL-GGFEIIP-------------
-----------------------------------PVVDVRLL-SIS----GKRSVPGGG
-SKVPQKKVNLAE-----------------------------------------------
------------------------------------------------ETEEK-APVK--
-KSIRDTPA-KNAQKSN-----QNGKDSKPS-TP-----------RSKGQESFKK--QEK
---TPKTPKVPTFI-EDIKKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFQ---------------M---TDQ---EAIQEL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQN-Y---LFGCEL--KADR-DYHFKVDNDEN----EHQLSSRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHL V--------A-VEEDAESEEEEEEEEVKLL-SIS----GKRSAPGSG
-SKVPQKKVKLAADEDDDDD----------------------------------------
---------------------------------DDDEDDDADDDFD-EEVEEK-APVK--
-KSVRDTPA-KNAQKSN-----QNGKDSKPSTPG----------S--KGQESFKK--QEK
---TPKTPKGPSSV EDIKAKMQAGIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MKD----SM-DMSPL----
--RPQ-NY---LFGFEL--KADN-VYHFKTDNDMN----EHQLSLRT---VS-LGA--GG
KGELR--IVEAEAINYEGS-PIKVT-LATLKMSVQPTVS-LGGC K---------------
----------------------------------------TLL-SMP----GKRSAPGGG
-NKVPQKKN---------------------------------------------------
--------------------------------------------DDDEEIEEK-VPVK--
-KSVRNTPD-KNAQKSN-----QNGKDLKPS-TP-----------R--------------
-------SKGPSSV EDSKAKMQASTE-KR-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------V---TDQ---EAIQDL--CQWRKSLKENDL
N--------------------------------------SLKYSVL-LNFYNR-------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMG----IPL----
--RPQ-NY---LFGCEL--KAYK-DYHFKVDNDEN----EHQLFLRT---VS-LGA--GA
KDELD--IVEAEAMNYKGS-PIKVT-LATLKMSVQPTVS-LGDSEITPP-V--ISRL-KC
GSGPVHIS-GQHL V--------A-VEEDAESEDE-EEEDVRLL-SIS----GKRSATGGG
-SKVPQKQVKLAADEDDGDDKD---------D----------------------------
--------------------------------------DGD-DDFDDEETEG-KAPVK--
-KSIQDTPA-KK---------------C--------------------------T--KEK
---TPKTPKGPSSV EDIKAKMQANVE-KG-------LSFPKVEAK--------FFN----
------YV--KNCFR---------------R---IYQ---EAIQDL--WQWRKS------
L-----------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSLL----
--RPQN-Y---LFGCEL--KADK-DDHFKVDNDEN----EHQLSLRT---IS-LGA--GA
KDELY--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHLV--------A-VEEDAESEDE-EEEDVKLL-SIS----GKRSAPGGG
-SKVPQKKVKLAADEDDDD---D-------ED----------------------------
---------------------------------D-DDEDDDDDDFDDEEAEEK-APVK--
-KSIRDTPA-KNAQKSN-----QNGKDSKPSSTP-----------RSKGQESFKK--QEK
---TPKTPKGPSSV EDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFQ---------------M---TDQ---EAIQDL--WQWRNLN-----
---------------------------------------NLLKIFRLISFL---------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQ-NY---LFGCEL--KAEK-DYHFKVDNDEN----EHELSLRM---VS-LGLGAAA
KDELH--IAEAEAMNYEGS-PIKVT-LATLKISVQPTVS-L GE-----------------
--------------------------------------DVKLL-SIS----GKRSAPGSG
-SKVPQKKTDEDDDDDD-------------------------------------------
----------------------------------DNDDEDDDHNDFDEEVEEK-APVK--
-KWIRDTPA-KNAQKSN-----QNGKDSKPS-TP-----------RSKGQESFKN--SVE
---------------DIKAKMHTSIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------I---SDQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQN-Y---LFGCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHL V--------A-VEEDAESEDE-EDEDVKLL-SIS----GKRSAPGGG
-SKVPQKKVKLAADEEDDDDDED-------------------------------------
---------------------------------DDDDDDDDDDDFDDEETEEK-APVK--
-KSVRDTPA-KNAQKSN-----QNGKDSKPSTPR----------S--KGQESIKK--QEK
---TPKTPKGPSSV EDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------VEDLMDMDM-DMSPW----
--RSQ-NY---LFGCEL--KADK-DCH-NVDNDEN----EHQLFLRT---VS-LGA--SA
KDELH--IVEAEA--------IKVT-LATLKMSVQQMVS-LGGFEITPP-V--VLQL-RH
GSGPVHIS-GQHLV--------A-LEEDAESEKE-EEEDVKLL-SIS----RKSSVPGSG
-SKVPQKKVKLAADEDDN------------------------------------------
----------------------------------------------DEEAEEK-APVK--
-KSIGDNPA-KNAQKSN-----QNGKDSKPSIRR------------S------KIK-QEK
---TSKTPKGPSSVEDSKAKMQARTE-KG-------GSLPIMEAK--------FIN----
------YL--NNCFG---------------M---TDQ---EAIKDL--WQWRRSLKESS-
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQN-Y---LFGCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHLV--------A-VEEDAESEDE-DEEDVKLL-GMS----GKRSAPGGG
-NKVPQKKVKLDEDDEDDED-----------D----------------------------
---------------------------------EDDDEDDDDDDFDEEETEEK-VPVK--
-KSVRDTPA-KNAQKSN-----QNGKDLKPLTPR----------S--KGQESFKK--QEK
---TPKTPKGPSSV EDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSSL----
--RPQN-Y---LFGCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDESH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLQL-KC
GPGPVHIS-GQHL V--------A-VEEDAESEDE-EEEDVKLL-SIS----GKRSAPGGG
-SKVPQKKVKLAVDEDDDDDDD--------------------------------------
-------------------------------------------EFDDEDTEEK-APV---
---------------------------------------------KKSGQESFKK--QEK
---TPKAPKGPSSV EDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------M-NMSPL----
--RPQ-NY---LFGCEL--KADK-NYQSKVDNDEN----EHQLSLRM---VS-LGA--GA
EDELH--IVEAEATNYKGS-PIKVT-LATLKMSVQPTVS-LGGFKVTPP-V--DLRL-KC
GSGPGHIS-GQHL V--------A-VEEDAESEDE-EEEDVKLL-TVS----GKRSAPGGG
-SKVPQKKVKLAADEDDDEDDD---------D----------------------------
----------------------------------DD-EDDD-DDSEDEEAKE-KGPVK--
-KSSNQNGK-DS---------------KPS-STP-----------KSKGQEFFKK--QEK
---TPKTPKGPSSV EDIKAKMQASIE-KG-------GSLCRVGAK--------FIN----
------YV--KNCFW---------------V---IDQ---EAIQDL--WQWRKF------
L-----------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQN-Y---LFGCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHLV--------A-VEEDAESEDE-DEEDVKLL-GMS----GKRSAPGGG
-NKVPQKKVKLDEDDDEDDE-----------D----------------------------
---------------------------------DEDDEDDDDDDFDEEETEEK-VPVK--
-KSVRDTPA-KNAQKSN-----QNGKDLKPSTPR----------S--KGQESFKK--QEK
---TPKTPKGPSSV EDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQ-NY---LFGCEL--KADK-DDHFKVDNDEN----EHQLSLRT---VS-LGA--SA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-M--VLRL-KC
GSGPVHIN-GQHLV--------A-VEEDAESEDA--DEDVKLL-SIS----GKRSAPGGG
-SKVPQKKVKLAADEDEDDEDD---------D----------------------------
---------------------------------D-DDDD-----SDDEETEEK-VPVK--
-KSVRDTPA-KNAQKSN-----QNGKD------------------------------SKS
---STPRSKGPSSVEDIKAKMQASIE-KA-------LKFYDSMPW--------HRRIG--
----ESF----------------------------------LIRNM--EDWHAKLSGNGL
E--------------------------------------VS-------------------
------KPDHNSEGT-----------FLSLV-----------------------------
-------------------

---------MSPAPSGPLIRALMDWVATCNKIKAGVGTCVSATESVWCCEYISRAGFRAG
AD--RTKIRREGRG--PRKRPRRRRGKGKGEGPQRRWL-VG--LAGGFCPISALSWG---
WH-----GRISIALLLPRCLGAASSSFSSFSTT----------LSPPPFLFSPLLPGR--
-------CRRVSR---TPMANL--SPSIVIDDDE--PGYD-LDLFCIPKHYAQDLEKVFI
PHGLIMDRTERLARDVMKEMGGHHIVALCVLKGGYKFFADLLDYIKALNRNSDKSIPMTV
DFIRLKSYCNPTEDRAQQLPVAHPSP-IARCLSY-----NCPTQ--NTDM-DVNHI----
--RAQ-SF---LFGCEL--KADK-DFHFKVINEQI----EHQLSLRT---VS-LGA--SA
KDELH--VVEAEALNFEGS-PTTVT-LASLKLSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVYIS-GQHLV--------A-LEEDVE-----ENN-VKAV-NLP----AKRAASEID
-NKIPQKKVKLSEEEEEEEEEEEDEEEEEEDDDEAEDEE EIEEVDEEEEEVEVEEEEEEE
VEEIEEEEEEEEEEGEEEEEEEEGEEEEEEGEEEEEEEEEGEEEEEEEEIENN-DPIEIK
SDPDSPAQN-GQTPNME-----EE-TDSEPV-TP-----------KSKSQESFETEEK--
---ITPSPQESSSPEDIKENIQND QS-TGDIKVIGGDDLSTLTGK--------SVL----
------FL--LDIID---------------T-----G---KTMQTL--LSLVKQYNPKMV
KVASLLVKRTPR-SVGYRPDF--------------------VGFEIPDKFVV--------
--GYALDYNE--YFRDLNHVCV------------------ISETGKDKYKA---------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------M-FILLD----
--LFYF-F---FTGCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-RC
GSGPVHIS-GQHL V--------A-VEEDAESEDE-DEEDVKLL-SMS----GKRSAPGGG
-SKVPQKKVKIDEDEDD--DDED-------------------------------------
---------------------------------DEDDEDDDDDDFDDEETEEK-VPVK--
-KSVRDTPA-KNAQKSN-----QNGKDLKPS-TP-----------RSKGQESFKK--QEK
---TPKTPKGPSSV EDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RSQ-NY---LFSCKL--KAE--HYHFKVDNDEN----EHQLSLRM---VI-LEA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LETLKMSVQPTVS-LGSFEITPP-V--VLRL-MC
GSGPVHIS-GQH LE-------------DAESDEE-EEEDVKLL-SIY----GKQSAPGSD
-SKVPQKKVKLAADEDDEDDDD---------D----------------------------
----------------------------------D--------F----------------
--------------DDA-----ENGKDSKPS-TS-----------RSKGQESFKK--QEK
---TPKTPEGPRSI EDIKAKMQASIE-KC-------DSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------CDSVLHSC---SLEQWLPISILLLSY-----HPMED--SVDM-DRSPL----
--RPQ-NY---LFGCKL--KANK-GYHFKVDNDEN----KHQIFKNG----Q-VRG--WC
KGELH--IVEAVVMNYEGS-PIKVP-LATLKISIQPTVT-GG-FEIMPP-V--VLQL-KC
CSGPVHIS-GQHLV--------V-VEEDAESED-----EKEEN-MNS----SCSKVP---
-----QKKVKLADEDVDD-------------HD---------------------------
-------------------------------------DEDDDGNFDEGEMEEK-APVK--
-KSVIETPA--NAQNSN-----QNGKDSKPS-AP-----------KSKGQESF-------
--KTPKTLKGPCSVEDIKAKMQASIE-KD-------ISLPRVEAR--------FIS----
------DV--KNYFR---------------M---TDQ---EAIQDL--WQWKKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQN-Y---LFGCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHL V--------A-VEEDAESEDE-EEEDVKLL-SIS----GKRSAPGGG
-SKVPQKKVKLAADEDDDDDD---------ED----------------------------
---------------------------------D-DDEDDDDDDFDDEEAEEK-APVK--
-KSIRDTPA-KNAQKSN-----QNGKDSKPSSTP-----------RSKGQESFKK--QEK
---TPKTPKGPSSV EDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DINPR----
--SPQ-NY---LFGCEL--QADK-DYHFKVDNDEN----E------T---VS-LGA--DG
KDELH--IVEAEAVYYEGS-PIKVT-LATLKMSVQPTIF-LRGFEITPP-V--VLRL-KC
SSGPVHIS-EQHL V--------A-VEED-------AEEDVKLL-SIS----GKWSAAGGG
-SKVPQKKVELATDEDDDDDDDD--------D----------------------------
---------------------------------DDNDEDDDNDDFDNEETEEK-A-----
--------------PPN-----QNGKD-------------------------------SK
---PSSTPRSNGSV EDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YM--KNCFR---------------M---TDQ---EAIQDL--WQLRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQN-Y---LFGCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHL V--------A-VEEDAESEDE-EEEDVKLL-SIS----GKRSAPGGG
-SKVPQKKVKLAADEDDDDDD---------EE----------------------------
---------------------------------D-DDEDDDDDDFDDEEAEEK-APVK--
-KSIRDTPA-KNAQKSN-----QNGKDSKPSSTP-----------RSKGQESFKK--QEK
---TPKTPKGPSSV EDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SVDV-DMSPL----
--KPQ-SY---LFGCEL--KADK-DYHFTVDNEGS----EHQSSLRT-------------
-DGLY--IVEAEIKNHEGS-PIKVT----LKISVQPIIS-LGGCEIIPP-V--VLWL-KC
GSGPMHIC-GQHL V--------A-MEEDEG-------N-VKLH-SIA----GKSSVPGSG
-SKFPQNKSKTYDDNNDEFDDDE-------------------------------------
---------------------------------------AFASSKEIYEI-----P-L--
-KIYMAILA-KKCTKSN-----QKGKDSKSS-RP-----------RSKGQEFFKNQEK--
---TTKTLTGSSFI EDIKAKVLASIE-KG-------GFLPKVEAK--------FIN----
------SV--SNCFW---------------M---TDQ---EAIQDL--WKWKKSF-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--KPQ-NY---LFGCEL--KADK-DYHFKVDNDEN----EHQLSLRM---IS-LGA--GA
KDELH--IVEAEAMHYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-RC
GSGPVHIS-GQ HPV--------A-VEEDAESEEE-DEEDDKLL-SMS----GKRSAPGSG
-SRVPQKKVKLDEDEEEEDEDD---------E----------------------------
----------------------------------DDE-DDD-DDFDDEETEE-KVPVK--
-----------------------------------------------KGQESFKK--QEK
---THKTPKGPSSV EDIKTKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EATQDL--WQWRKS------
L-----------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
-------------SCEL--KADK-DYHFKVDNDGN----EHQLSLRM---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSGQPTVS-LGGFEITPP-V--ILWL-RC
GPGPVHIS-GQHL V--------A-VEEDADSEDE-DEEDIKLL-TMS----GKRSAPGGG
-SKVPQKKVKIDED----------------------------------------------
--------------------------------------EDD-DDFDDEETED-KVPVK--
-KSI-KRSR-VL---------------------------------------QKTE--KKK
---TPKTPKGPSSV EDIKAKMQASIE-KG-------GSLPKVESK--------FIN----
------YV--KNCFQ---------------M---TDQ---EAIQDL--WQWRKF------
L-----------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQN-Y---LFGCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHLV--------A-VEEDAESEDE-EEEDVKLL-SMS----GKRSAPGGG
-SKVPQKKVKLAADEDDDDE----------------------------------------
-----------------------------------DDDDDDDDDFDDEETEEK-VPVK--
-KSIRDTPA-KNAQKSN-----QNGKDSKPSSTP-----------RSKGQESFKK--QEK
---TPKTPKGPSSVEDIKAKMQASIE-KE-------H-----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SADM-DMSLL----
--RPQN-Y---LFGCEL--KADK-DYHFKVDNDDN----EHQLSLRT---VS-LGA--GA
KDELH--SVEAEAMNDEGG-PIKVT-LATSKMSVQPAVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHL V--------A-VEEDAESEEE-EEEDVKLL-STS----GKRSAPGGG
-SKFPQKKVKLTADEDDEDDEDE-------------------------------------
---------------------------------D-----EDDEDEDDEETEEK-APVK--
-KSILDTPA-RNAQKSN-----QNGKDSKPSTP------------RSKGQESFKK--QEK
---SPKTPKGPSSV EDIKAKMQASTE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------VED--SRDVDMDMSP----
--LNQ-NC---LFGCEL--KADE-DYHFKVDNDA-----NHQLSLRT---VS-LGA--DA
KDY--------RTMNYDDG-SIKAT-LATLKMSVQLTFS-LGGFEIPPP-M--VLRL-KC
GLGTVHIS-GQHLV--------A-MEKDAESEDE-GEKDVKLL-GTS----GKQSAPGGG
-SKVPPKKVKLAAEEEEEG-----------------------------------------
---------------------------------------EEEEDFDEEETEEK-TPIK--
-R-------------S---------------------------------RILKKKQK---
--KAPKTPKGPSSIEDSKPK----IIEKG-------GSLPKVEAK--------FIN----
------FV--KNCFG---------------I---TDQ---EAIQDL--WQWRKCL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MEE--SMDM-NMSPL----
--RSQ-SY---LFSCEL--KADK-DYHFKVDNDEN----QHQL-------------GAGA
KEELH--IVEAEAMNYEGS-PIKAT-LATVKMSVQPTVS-LGGFEIT-------------
--PLV-------------------------------VLYVKLL-SMS----GKRSAPGGV
-SKVPQKKVKRASDEDDEDEEGEEEEEEEDEE----------------------------
---------------------------------EDDDDEDDDDDFDEEEAVEK-APVK--
-KSIRDTPA-KNTQKSN-----QNGKDSKPS-AP-----------RSKGQESFKK--QEK
---TPKTPKGPSSVEDIKAKMQASIE-KA-------H-----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--LMDM-DMSPL----
--KPQN-Y---LFGCEL--KA--------VDNDEN----EHQLSLRT---GS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTIS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHL V--------A-VEEDAESEDE-EEEDVKLL-SMS----GKRSAPGGG
-SKVPQKKVKLAADEDDDE-----------------------------------------
------------------------------------DEYDDDDDFDDEETEEK-VPVK--
-KSIRDTPA-KNAQKSN-----QNRKNSKPSTP------------RSKGQESFKK--QEK
---TPKTPKGPSYV EDIKATMQASIE-KG-------GSLPKVEAE--------FTN----
------YV--KNCFR---------------M---NDQ---EAIQDL--WQWRNLN-----
---------------------------------------NLLKIFRLTSFL---------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
MLIVNVSWYDSILSGC---SLEQRSFISICLLSHLSVCRHLIED--SMDM-DMSPL----
--RPQ-NY---LFGCEL--KADK-DDHFKVDNDEN----EHQLSLRT---VS-LGA--GT
KDELH--IVEAEAMNYEGS-PIKVT-LVTLKMSAQPTVS-LGGFEITPP-V--VLRF-KC
GSGPVHIS-GQHL V--------A-VEEDAESEDE-EEEDVKLL-SIS----GKRSAPGGG
-SKVPQKKVKLAVDEDDDDDED---------D----------------------------
--------------------------------------DDD-DDFDDEEAEE-KV-----
----------------------------------------------SKGQESFKT--QEK
---TPKTPKGSSSV EDIKAKMQASIE-KG-------GSLPTVEAE--------FIN----
------FV--KNCFW---------------M---TDQ---EAIQDL--WQWRKS------
P-----------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQ-NY---LFGCEL--KADK-DYHFKVDNDDN----EHQMSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPT-V--VLRL-KC
GSGPVHIS-EQHLV--------A-IEEDAESEDE-DGEDVKLL-GMS----GNRSAPGGG
-NKVPQKKVKLDEDDEDD------------------------------------------
---------------------------------------NDDDDFDEEETEE-KVPVK--
-KSVQDTLA-KNAQKST-----QNGKDLKPST-P-----------RSKGQESFKK--XKK
---IIASEA---------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--LMDM-DMSPL----
--RPQ-NY---LFNCEL--KVDK-DYHFKFDNDEN----EHQLSLST---VS-LGA--GA
KGDLH--IVKAEPMNYEGS-PIKVT-LATLKMSVQSMVS-IGGFEITPS-L--VLWL-NC
GSGPVHIS-GQHL V--------A-VEENAESEDE-EEEDVKLL-SIS----GK-------
--S---------------------------------------------------------
------------------------------------------------------------
-------KG-QES----------FKKQ-------------------------------KK
---SPKTPERPSSVEY IKAKMQASTE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFQ---------------M---TDQ---EAIQYL--WQWWKSLEENSL
N--------------------------------------NLLKIFRLISFL---------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMGM-DMSPL----
--SPQ-NY---LCSCEL--KANK-YYHCKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLWL-K-
GSGPVHVS-GQHLV--------A-VEED--------------------------SAPGCG
-SKVPQKKVKLAADEDDDNDE---------------------------------------
-------------------------------------EEEEEDNFDEPETEE-KASVK--
-KSVQD-PA-KNAQKSN-----QNGKDSKPST-P-----------RSQGQESFKK--QEK
---TPKTPKGPSLVEDIKAKMQASIE-K--------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQN-Y---LFGCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHL V--------A-VEEDAESEDE-EEEDVKLL-SIS----GKRSAPGGG
-SKVPQKKVKLADEDDE-DE--D-------ED----------------------------
---------------------------------EDEDEDDDDDDFDDEETEEK-APVK--
-KSIRDTPA-KNAQKSN-----QNGKDLKPSTPR----------S--KGQESFKK--QEK
---TPKTPKGPSSV EDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------VDM-EMRPL----
--RPQ-NY---LFSCEL--KANK-DYHFKVDNNEN----EHQLSLRA---IN-LGA--GA
MDELD--TVEAEAMNYEGS-PITVT-LATLKMSVQPTVS-LGGFEITPP-V--VLQL-KC
GSGPVHIS-GYHLV--------A-VEEDAESEDE-EKEDVKLL-SIS----GKQSAPGDG
-SKLPQKKVKLAADEDDDGDD---------------------------------------
--------------------------------------------FDDEETEE-K------
-APVKDTPV-KNAQKSN-----QNGKDSKPSSTP-----------RSNGRESFKK--QQK
---SPETPKGPSSVEDIKAKMQASIE-KG-------SSTPKVEAK--------LIS----
------YM--------------------------TDQ---EVIQDL--------------
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------GCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEALNYEGN-PIKVT-LASLKMSVQPTVS-LGGFEITPP-V--GLRL-LC
YSSTYKLTSENSLL--------A-LEEDAESDDE-EEDDMKLL-NMS----GKRSAPGVA
-SKVPQKKVKLSEEDEDDDEED---------D----------------------------
---------------------------------D--DEDDDDDDFEDEESEEKTPPVK--
-KSIRDTAA-KNAQKSN-----QNGKDS-KPSTP-----------KSKGQESFKK--QDK
---TPKTPKGPTSLEDIKAKMQASIE-KA-------FSLAYILWE--------FPPG---
-----------ICSS---------------M---RL-----KRLEF--WFWGRIF-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
MLIVNVSWYDSILSGC---SLEQRSFISVRLLSHLSVCRHPIED--SMDM-DMSPL----
--RPQ-NY---LFGCEL--KADK-DDHFKVDNDEN----EHQLSLRT---VS-LGA--GT
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSAQPTVS-LGGFAITPP-V--VLRF-KC
GSGPVHIS-GQHL V--------A-VEEDAESEDE-EEEDVKLL-SIS----GKRSAPGGG
-SKVPQKKVKLAVDEDDDDDDD--------------------------------------
----------------------------------------D-DDFDDEEPKM-HTSQI--
-R----MEK-TQ---------------NHH-QHQ-----------DQKDKNPSKH--RKK
---TPKTPKGSSSA EDVKAKMQASIE-KG-------GSLPRVEAE--------FIN----
------FV--KNCFW---------------M---TDQ---EAVQDL--WQWRKS------
P-----------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------CHYPMED--LMDM-DMNPL----
--RPQ-NY---LFGCEL--KANK-DYHFKVDNDEN----EYQLSLRT---VS-LGA--GA
KDELH--IAETEAMNYEGS-PIKVT-LTTLKMSVQPTVS-LGGFEIMR--V--VLQL-KC
DSGPVHIS-GQHLV--------A-VEEAELEDEE-EDYDE----EME----E--KAP---
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------MGM-DMSSL----
--RPQ-NY---LFSCEL--KADK-DYHFKVANDEK----EHQLSLRK---VS-LGA--GA
KDELH--MVEAEEMNYEGN-PIKVT-LATLKMPIQPTVS-LGGFEITPP-V--VLWL-RC
GSEPVHIS-GQH LA--------A-VEEDSESEDE-DEEDVKLL-SMS----GQRSAPGGG
-SRVPQKKVKINEDEDEDDE----------------------------------------
----------------------------------------DDEDDGDEEIEE-KVPVK--
-KSVCDTPA-KNAQKSN-----QNGKDLKPST-P-----------RSKGQ--------EK
---TPKTPKGPSSV EDIKEKMQASIE-KG-------GSLPKVEAK--------F------
--------------------------------------------IN--YQWRRSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQ-NY---LFGCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTE----------------------
---------------------------DAESEDE-EEEDVKLL-SVS----GKRSAPGGG
-SKVPQKKVKLAADEDVDDDED---------D----------------------------
---------------------------------DDDDEDDDDDDFDDEETEE-KAPVK--
-KSIRDTPA-KNAQKSN-----QNGKDSKPT-TP-----------RSKGQESFKK--QEK
---TPKTPKGPSSVEDIKAKMQASIE-KG-------GSLPKVEAK--------FVN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--LMDM-DMSIL----
--NSQ-NY---LFGCEL--KADK-DHHFKVFNDEN----ENQLSLRM---VS-LGT--VA
KDELH--IVEAETMNSEGR-PIQVA-LTTLEMSVQPR-I-LGGLEIAPP-V--VG-S-N-
---------------------------------E-QGEDVKLK-YI---------WKTIC
SA----------------------------------------------------------
---------------------------------------GDSKVPQKKETEAK-ASVK--
-KSIRDTPD-KNAQKSN-----QSGKDSKPS-AP-----------RSKGQE---------
---SPRTPKGPSSVED-KAKLQASIE-NG-------SSFSKVEAK--------FIN----
------YY--VWNVM---------------I---GQS---SSSGQ---------------
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--LMDM-DMSPE----
--PD------------------K-DYHFKVDNDEN----EHQLSLRT---FS-LGAGAGV
KDELH--IIEAEAMNYEGS-PIKVT-LATLKMSVQPMVS-LGGFEIIPP-V--LLWL-KC
GSGPVHIS-GQHL V--------V-VEEDAESEDE-EEEDVKLL-SIS----GKH------
--RVPQKKVKLAANEDE----E---------D----------------------------
-----------------------------------D------DDFDDEEAEE-KAPVK--
-KSIQDISA-INAQKSN-----QNGKDSKA-STP-----------RSKGQESFKK--QEK
---TPKTPKGPSSV EDIKAKMQASIE-KG-------GSLPKVEAT--------FIK----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------M-EMRPL----
--RPQ-NY---LFSCEL--KANK-DDHFKVDNNEN----EHQLSLRA---IS-LGA--GA
MDELD--TVEAEAMNYEGS-PITVT-LATLKMSVQPTVS-LGGFEITPP-V--VLQL-KC
GSGPVHIS-GHHL V--------A-VEEDAESEDE-EKEDVKLL-SIS----GKQSAPGGG
-SKLPQKKVKLAADEDDDGDD---------------------------------------
--------------------------------------------FDDEETEE-K------
-AP------------SN-----QNGKDSKPPSTP-----------RSNGQESFKK--QQK
---SPETPKGPSSV EDIKAKMQASIE-KG-------SSIPKVEAK--------VIS----
------YR--------------------------KSL-----------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--LMDM-DMSPL----
--RPQ-NY---LFNCEL--KVDK-DYHFKFDNDEN----EHQLSLST---VS-LGA--GA
KGDLH--IVKAEPMNYEGS-PIKVT-LATLKMSVQSMVS-IGGFEITPP-L--VLWL-NC
GSGPVHIS-GQHL V--------A-VEENAESEDE-EEEDVKLL-SIS----G--------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------KSKGQESFKK--QKK
---SPKTPERPSSVEY IKAKMQASTE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFQ---------------M---TDQ---EAIQDL--WQWWKSLEENSL
N--------------------------------------NLLKIFRLISFL---------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMEM-DMSPL----
--RPQ-NF---LFGCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEALNYEGN-PIKVT-LASLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHVS-GQHLV--------A-LEEDAESDDE-EEDDMKLL-NMS----GKRSAPGVG
-SKVPQKKVKLSEEDEEDDEED---------D----------------------------
----------------------------------DDEDDDDDDFEDEESEEK-TPPVK--
-KSVRDTAA-KNAQKSN-----QNGKDSKPS-TP-----------KAKGQDSFKK--QDK
---TPKTPKGPTSLEDIKAKMQASIE-KG-------GSLPKVEGK--------FIN----
------YV--KNCFR---------------M---SDQ---EL------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQN-Y---LFGCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHL V--------A-VEEDAESEDE-EEEDVKLL-SIS----GKRSAPGSG
-SKVPQKKVKLAADEDDDEDDDD-------------------------------------
---------------------------------DDDDEDDDDDDFDDEEAEEK-APVK--
-KSIRDTPA-KNAQKSN-----QNGKDSKPSTPR----------S--KGQESFKK--QEK
---TPKTPKGPSSV EDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQ-NY---LFGCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFE-ITP-----------
----------PV----------------VVKL-----LS------IS----GKRSAPGGG
-SKVPQKKVKLAA-----------------------------------------------
-----------------------------------------E-----EEAEE-KAPVK--
-KSIRDTPA-KNAQKSN-----QNGKDSK-PSTP-----------RSKGQESFKK--QEK
---TPKTPKGPTSVEDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQN-Y---LFGCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHLV--------A-VEEDAESEDE-EEEDVKLL-SIS----GKRSAPGGG
-SKVPQKKVKLAADEDDDDDD---------ED----------------------------
---------------------------------D-DDEDDDDDDFDDEEAEEK-APVK--
-KSIRDTPA-KNAQKSN-----QNGKDSKPSSTP-----------RSKGQESFKK--QEK
---TPKTPKGPSSVEDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDV-DMSPL----
--RPQ-NY---LFGCEL--K--------------------HQLSLGT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-L--------PTIS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHLV--------A-VEEDAESEDE-EEEDVKLL-SIS----GKRSAPEGG
-SKVPQKKVKLAADEDDDDD----------------------------------------
---------------------------------------DD-DDFDDEEPKE-K------
------------------------------------------------------A--S EK
---TPKTPKGPSSV EDIKAKMQASIE-KS-------GSLPKVEAK--------FIK----
------YV--KNCFW---------------M---TDQ---EAIQDL--WQWRKS------
L-----------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--LMDM-DMSSL----
--EPQ-NF---FFDWKL--KADQ-DYHFRVDNDEN----EHQLSLRV---VR-LRA--GT
KYELH--VVEAETMNYEGS-PIKVT-S------VQPMVS-LGGMKIKPV-V--FC-W-KC
GSKQSVSG-SGSKV--------R-------------------------------------
------------------------------------------------------------
---------------------------------------------QKEETEEH-VQWK--
-KSIRETPA-KNAQKSN-----QNGKESKQS-IS-----------KRS-RIFQKQ-----
E-KVPKSLKGSSSVEDIKAKMQARIK--S-------GSLTKVEVK--------FIN----
------CM--KNCFW---------------M---TDQ---ETIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--LMDM-DMSLL----
--RPQ-NY---LFGCEL--KANK-DYHFKVDNDEN----EHQLSLRM---VS-LGA--GA
KDELH--IVEAEAMNYEGS-LIKVT-LASLKMSVQPAAS-LGGFEITPP-V--VLQL-KC
GSGPVHIS-R QCLV--------A-VEEDAESEDE-EEEDVNLL-SIS----GKRSASGGG
-SKVPQKKGKLAAADDDDDDED---------D----------------------------
----------------------------------DDENDDN-DDFDDEEAE---------
------------------------------------------------------------
--------EKHDSV EDIVAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFQ---------------M---TEQ---EATQDL--WQWRKS------
F-----------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQ-ND---LFSCEL--KADK-DYQVKVDNDEN----EHQLSLRT---VS-LGA--GA
EDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEIIPP-V--VLRL-KY
GSGPVHIS-GQHLV--------A-VEEDGESDEE-EEEDVKLL-SIS----GN------G
-SKVPQKKT-------DEDV----------------------------------------
---------------------------------------DDEEDDDDDEAEE-KAPVK--
-KSIQDTPA-KNAQKSN-----QNGKDSKPS-TP-----------RSKGQESFKK--QEK
---TPKTPKGPSSVEDIKAKMQASIE-KA-------H-----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQN-Y---LFGCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPAVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHLV--------A-VEEDAESEDE-EEDDVKLL-NIF----GKRSAPGSG
-SKFPQKKVKLADEDDDDDD----------------------------------------
---------------------------------EDDDEDDDDDDFDDEETEEK-APVK--
-KSVRETPA-KNAQKSN-----QNGKDSKPSTPK----------S--KGQESFKK--QEK
---TPKTPKGPSSVEDIKAKMQASIE-KD-------GSLPKVEAK--------FIN----
------YV--KNCFQ---------------M---TDQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SVDM-DMSPL----
--RPQN-Y---LFGCEL--KADK-DYHFKVDNDEN----EPQLSLRT---VS-LGA--GA
KDELH--IVEAE----EGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHLV--------A-VEEDAESEDE-EEEDVKLL-SIS----GKRSAPGGG
-SKVPQKKVKLAADEDDDDDD---------ED----------------------------
---------------------------------D-DDEDDDDDDFDDEEAEEK-APVK--
-KSIRDTPA-KNAQKSN-----QNGKDSKPSSTP-----------RSKGQESFKK--QEK
---TPKTPKGPSSV EDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRNLN-----
---------------------------------------NLLKIFRLISFL---------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SVDT-DMSPL----
--RLQ-NY---LFGCEL--KADK-DYHFKVDNDEN----K------T---IS-LGA--GA
KDKLH--IVEAEAMSYEGS-PIKVT-LLTVSL--------AG-FKITPP-V--C FIA---
----------------------V--EKDAESEDQ-KEEDVKLL-SIC----GKPSVSGCG
-SNIPQKKVKFGASGDDD------------DND---------------------------
-------------------------------------DDDDDDDFDDKEAEEK-------
----------------P-----PNGKYSKPP-TP-----------RSKGQASFKK-----
QEKTPKTPKGPSYV EDIKAKMQPSVK-KG-------DSLPKVEVK--------FIS----
------YM--KNCFW---------------M---TDQ---GPL-----------------
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------T--GMYV-DTSPL----
--RPQ-NY---LFGCEL--KADK-DYHFRVDNDEN----EHQLFLRT---VS-LGP--GA
KDELD--IVEEQ----GGN-PIKVT-LAALKMSVQPTVS-LGGFEITPL-V--ILWL-KC
GSEPVHIS-GYHLA--------V-VEEDAESQDE-E-EDVRLL-SIS----GKQPAPGSS
-SKFPQKKVKRAADKHDG------------------------------------------
----------------------------------DDKDNDNDDKFDDEETEEK-APVK--
-KSVQDTP--KNAQKSN-----QNGKDSKPSSTP-----------RTKGQEFFIK--QEK
---SPKTPKGPSSIEDIKAK-QANVE-KG-------GSLPKMEAK--------FFN----
------YV--KNCFW---------------R---IYQ---EAIQDL--WQWRK-------
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------FGCEL--KADK-DYHFKVDNDDE---NEQQLSLRM---VS-VGA--GA
KDELH--TVEADAMNYKGS-PIKVT-LATLKVSIQPTVS-LGSFAITPS-V--VFQL-KC
GSGPVHIS-GQHSV--------A-VEEDAESEEE-EE---ELL-SIS----EKHSAPGRG
-WK---GKVKLAADEDDDDDDN---------D----------------------------
------------------------------------------DDSDDEEAEEM-------
---FQETPA-KNVQKSN-----QNGKESK----P-----------STPRKESFEK--QEK
---TPKTPKGPSSIEDIK-KVQASIE-KG-------GSFPKVEAK--------FIN----
------YM--KDCFW---------------M---TDQKATE---YL--RQRTKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQN-Y---LFGCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHLV--------A-VEEDAESEDE-EEEDVKLL-SIS----GKRSAPGSG
-SKVPQKKVKLAADEDDDDEDDD-------------------------------------
---------------------------------EDDDEDDDDDDFDEEEAEEK-APVK--
-KSIRDTPA-KNAQKSN-----QNGKDSKPSTPR----------S--KGQESFKK--QEK
---TPKTPKGPSSVEDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MGD--SMDM-DLSPL----
--RPQN-Y---LFSCEL--KADK-DDHFKVDNDEN----EHQLSLRM---VN-LGA--GA
KDELH--IVEAEEMNYKGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHL V--------T-VEEDAESEDE-EEEDVKVL-SIS----GKRSALGDG
-SKVPQKKVKLAADEDDDDDE---------------------------------------
-------------------------------------DDDDDDDFDDEEAEEK-APVK--
-KSIRDTPA-KNAQKSN-----QNGKDSKLSSTP-----------RSKGQESFKK--QEK
---TPKTPKGPN----IKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFW---------------M---TDQ---EAIQDL--WQWRNLN-----
---------------------------------------NLLKIFHLISFL---------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------MDM-DMSPL----
--RPQN-Y---LFSCEL--KANK-DYHFKVDNDKN----EHQLSLRT---VS-LGA--GA
KDELH--ILEGEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQH LA--------V-AEEDAESGEE-EEEDVKLL-SIS----GKRSAPGSG
-SKVPQKKVKLAADEDDDDDDDD-------------------------------------
-----------------------------------DDDEDDDDDFDEEEAKEK-A-----
----------------------PNGKDSKPSTP------------RSKGQESFKK--QEK
---TPKKPKEPSSV EDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YM--KNCFQ---------------M---TDQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--LMDM-DMSPL----
--RSQ-NY---LFGCEL--KADK-DYHFKVDNDEN----EHLLSLRT---VS-LGA--GA
KDELH--LVEGEAMNYEGS-PIKVT-LATLKMSGQPTVS-LGGFEITP--V--VLRL-KC
VSGPEHVS-GQHLV--------A-VEGDAESEDE-EEEDVKLL-SIS----GQRAAPGSG
-SKFPQKKSKTFCD----------------------------------------------
------------------------------------------NDFDEEEMEE-KAPR---
------NSA-KNAQKSN-----QNGKDS-----------------KSKGQESFKK--QEK
---NPKTPKGPSSVEDIKAKMQASIE-K--------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQ-NY---LFGCEL--KADK-DYHFKVDNDEN----EHELSLRT---VS-LGA--GV
KDELH--IVEAEAMNYEGS-PIKVT-LATVKMSVQPMVS-LAGFEITPL-V--VLRL-KC
GSGPVHIS-GRHLV--------A-VEEDAESGDE-EEEDVKLL-SMS----GKRSA----
--KVPQKKVQLAADEDDDYEDE--------------------------------------
----------------------------------DDDEDDDDDDFDDEETEE-KVPVK--
-KSICNTPA-KNAQKSN-----QNGKDSKPSSMR-----------RSKGQESFKK--QEK
---TPKTPKGPSSVEDIKAKMQASIE-KA-------H-----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMSM-DMSPL----
--RPQ-NY---LFSCAL--KADK-DDHFKVDNDEN----EHQLSLRM---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTAS-LGGFEIAPL-V--VLRL-KC
GSGPVHIS-GQHLV--------V-VEEDAESEDE-EDEDVKLL-SIS----GKRSAPGGG
-SKFPQKKVKLAADEEDDDDD---------------------------------------
-----------------------------------EDDDDDDDDFDEEETEE-KAPVK--
-KSVRDTPA-KNAQKSN-----QNGKDSKPST-P-----------RSKGQESIKK--QEK
---TPKTPKGPNSVEDIKAKMQASIE-KG-------IFFGLVWF---------LGSEF--
------------------------------------H---SIAQAE--VQ----------
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQN-Y---LFGCEL--KADR-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHLV--------A-VEEDAESEEE-EEEEVKLL-SIS----GKRSAPGSG
-SKVPQKKVKLAADEDEDDDDDD-------D-----------------------------
---------------------------------DDDEEDDDDDDFD-EEVEEK-APVK--
-KSVRDTPA-KNAQKSN-----QNGKDSKPSTPR----------S--KGQESFKK--QEK
---TPKTPKGPSSVEDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRKSL-----
---------------------------------------LLKIFRLIS--F--------L
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMGPL----
--RSQ-NY---LFDCEL--KADK-DYHFKVDNDEN----EHQLSLRM---VS-LGT--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPMVS-LGGFEITSP-V--VLWL-NC
GSGSVHIS-GQHL V--------A-VEEDAESEDE-EDEDVKLL-----------------
------------------------------------------------------------
------------------------------------------------------------
-----NTPA-KNAQKSN-----QNGKDSKP-STP-----------RSKGQESIKK--QEK
---TPKIPKEPSSV EDIKVKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRKS------
L-----------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------LAD--SMDL-HMSPL----
--RLQ-NY---LFSWEL--KANK-DYHFKVDNDEN----EHQLSLRM---VS-LGT--GA
KEELH--IVEAEAMNCEDS-PINVT-LATLKMSVQPTVF-LGGFCGS-------------
--GPVHTS-GQHL V--------A-VEEDAESEDE-EEEDVKLL-SIC----RKQSAPGGG
-SKIPQKKVKLAADEED-------------------------------------------
----------------------------------DDDEEDDDDDSDDGETEEK-APVK--
-KSLQDTPA-KNAQKSN-----QNGKDSKPS-ST-----------PTKNR--------KK
---LLKTPKGPSSV EDIKAKMQASIE-KG-------GSLPKVEAK--------FIS----
------YV--KNCFQ---------------M---TGQ---EAIQDL--WQWRQSLEENSL
S--------------------------------------NLLKIFCCRARWLTPVIPV--
-LWEAEAG--GSRGQEFKTSLA-NMVKPSLY-----------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------CHHLMED--LMDV-DMSSL----
--KPQ-NY---LFGSEL--KADK-DYHFKVDNNEN----EHKLSVRM---VS-LGA--GT
KDELH--IVEAEAITYEGS-PIKVT-LATLKMSVQPMVS-LGGFEIIPP-V--VLWL-KL
VLGC-AYS-GQHLV--------A-VEEDAESEDE-EEEDDEET-EEK----A----P---
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMRPL----
--RPQ-NY---LFDCEL--KANK-DYYFKVDNDEN----EDQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLQL-KC
GSGPVHIS-G-HLV--------A-VEEDAESEDE-EEEDVKLL-SMS----GKQSAPGSS
-SKVPQKQVKLAADEDEDDDE---------------------------------------
---------------------------------------AD-DDFDDEETME-RIQ----
---------------------------------------------NHQHQDQKKK--QEK
---TPKTPKGPSSVEDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNYFQ---------------T---TDQ---EAIQDH--WQWTKS------
L-----------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--AMDM-DMSPL----
--RPR-NY---LFGCEL--KADK-DDHFKVDNDEN----KHQLSLRT---VS-LGA--GA
KDELH--IVEAQAMNYEGS-PTKVT-LATLKMSVQPMVS-PGGFEV---------TP-PC
GSGPVHIS-GQHL V--------A-VEEDAR-EDE-EEGDVKLL-SIS----GKRSAPGGG
-SKVPQKKVKLAADEDDDDDDE--------------------------------------
---------------------------------------DDDDDFDDVETKE---KV---
---------------------------LKTIINN-----------KIKRTRILQKT-GKK
---TPKTPKGP TSIEKGGSLPKVEAK-FI-------NYVEELLL----------------
----------DD------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------LED--CLDM-DMSPL----
--RPS-CFFSSLTGCEL--KADK-DYHFQVENDEN----EHQLSLQT---VR-LGA--GA
KDAKW--TALSRYVIFI-----IFY-AATLSQLDYCLYS-RFKWELETP-V--ILHI---
--KPSNLI-KKFIL--------A-VEED-ESEDD-EEEDV--K-LMS----GKRSAPGGG
-SKVPQKKVKLAADGDDEDDDEDED-----------------------------------
-------------------------------------DEE--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQN-Y---LFGCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHL V--------A-VEEDAESEDE-EEEDVKLL-SIS----GKRSAPGGG
-SKVPQKKVKLAADEDDDDDD---------ED----------------------------
---------------------------------D-DDEDDDDDDFDDEEAEEK-APVK--
-KSIRDTPA-KNAQKSN-----QNGKDSKPSSTP-----------RSKGQESFKK--QEK
---TPKTPKGPSSV EDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------MDM-DMSPL----
--RPQ-DY---LFGCEL--KANK-DYHIKVDNDEN----EHQLSLRT---VS-FGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFGITPP-V--VLRL---
--------------------------------------------NIS----GKQSAPESG
-SKFPQKKVKLAADADDD------------------------------------------
-------------------------------------DDDDDNDFDEEEAEE-KAPVK--
-KLIRDTLA-KNAQKSN-----QNGKDSK-PSTP-----------RSKGQESFKK--QEK
---TPKTPKGPK---------------KG-------GSLPKVEAK--------FIN----
------YV--KNCFW---------------M---TDQ---E---------WRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--LMDM-DMSPL----
--RPQ-NY---LFNCEL--KVDK-DYHFKFDNDEN----EHQLSLST---VS-LGA--GA
KGDLH--IVKAEPMNYEGS-PIKVT-LATLKMSVQSMVS-IGGFEITPP-L--VLWL-NC
GSGPVHIS-GQHL V--------A-VEENVESEDE-EEEDVKLL-SIS----GN-------
--KFPQKKVKLAAADEEEDDD---------------------------------------
-------------------------------------NEEDGDDFDDQETEEK-VPVK--
-KSITSYSR-QES----------FKKQ-------------------------------KK
---SPKTPERPSSVEY IKAKMQASTE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFQ---------------M---TDQ---EAIQDL--WQWWKSLEENSL
N--------------------------------------NLLKIFHLISFL---------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQN-Y---LFGCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHL V--------A-VEEDAESEDE-EEEDVKLL-SMS----GKRSAPGGG
-SKVPQKKVKLAADEDDDDEDDD-------------------------------------
---------------------------------D-DDDDDDDDDFDDEETEEK-VPVK--
-KSIRDTPA-KNAQKSN-----QNGKDSKPSSTP-----------RSKGQESFKK--QEK
---TPKTPKGPSSV EDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQ-NY---LFGREL--KADK-DYHFKVDNDEN----EHQLSLRM---VS-LSA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPMVS-LGGFE-ITP-----------
----------PV----------------VSDD-----EDVKLL-SVS----GKRSAPAGG
-NKVPQKKLKLEET----------------------------------------------
--------------------------------------------------EE-KV-----
--PVKDTPA-KNAQKSN-----QKRKDSK-PSTP-----------RSKGQESFKK--QEK
---TPKTPKGPSCVEYIKAKMQTSIE-KG-------GSIPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQN-Y---LFGCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHLV--------A-VEEDAESDDE-EDEDVKLL-SMS----GKRSAPAAG
-NKVPQKKVKLAADEDDDEEDDD-------------------------------------
---------------------------------DDDDEDDDDDDFDDEETEEK-VPVK--
-KSVRDTPA-KNAQKSN-----QNGKDSKPSTPR----------S--KGQESFKK--QEK
---TPKTPKGPSSVEDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------IE--DKTA-LLSPL----
--QPQ-NY---LFGCEL--KADK-DDHFKVDNDEN----EHQLSLRT---VS-LGT--GA
KDELH--IIESEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHLV--------A-VEEDAESEDE-EEEDIKLL-SVS----GKRSAPGGG
-SKVPQKKVKLAEEDEEEEDED---------E----------------------------
---------------------------------E-DDDD-----FDDEE-EEK-V-----
----------------------PTGKD------------------------------SKP
---AIPRSKGPSSVEDIKAKM---------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------VED--SMDM-GMSLL----
--RPQ-NY---LFGYKL--KADK-DYDFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTFS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHL V--------A-VEEDAESENE-DEEDVKLL-S--------------G
-NKVPQKKVKLDKNDDDED-----------------------------------------
--------------------------------------DDD-DDFDDEEAEE-KVPIK--
-GSRVL----------------------------------------------QKT--RKN
---PPKIPKGPSSV EDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFW---------------V---ADQ---ELSL----------------
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQ-NY---LFGCEL--KVDK-DYHFK-------------LSLRM---VS-LGA--GA
KDELY--IVEAEAMNYKGS-PIKVT-LATLKMSVVPTVS-LGGFEITSP-V--VLRF-KC
DSGPVHIS-GQHL V--------A-VEEDEE--------DVKLL---------------CG
-GKIPQKKVKLAADEEDDDD----------------------------------------
---------------------------------EDDDDEDDDDDFDDEEAKEK-APDK--
-NP-------------------------------------------------SKN--RKK
---LLKHLKGPSSV EDIKAKMQASIE-KC-------GSLPKVEAK--------FIS----
------YV--KNCFW---------------M---TEQ---EAIQDF--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DISPM----
--RPQ-NY---LFSCEL--KADK-DDHFKVDNDEN----EHQLSLRM---VR-LGA--GA
KDELL--IVEAEAMNYEGS-PIKVT-LATLKISVQPMVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHLV--------A-VEEDSESEDE-EEEDVKLL-SIS----GKQSAPGGG
-NKIPQKRVKLADEDD--------------------------------------------
-----------------------------------DDDEDDDDDFDDEEAEE-KAPVK--
-KSIRDTPA-KNPQKSN-----QNGKDSKPSV----------------------------
--------------EDIKAKMQASIE-KV-------H-----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--LMDM-GMSLL----
--RPQ-NY---LFGCEL--KADK-DDHFKVDNDEN----EHQLSLRT---VS-LGA--GP
KDELH--IVEAEAMNYEGSSNLKVT-LATLKMSVQPTAF-PGGFEITPP-V--VLQL-KC
CSGPVRIS-RQCLV--------A-VEEDAESEDE-EEEDVK-L-SIS----GKRSALEGG
-RKVPQKKVKLAADEDDDDDEN---------D----------------------------
----------------------------------------DDDDFDDKET----------
-----------------------------EPSTP-----------RSKGQESFKK--KEK
---TPKTQKGPSSVEDIKMQAVRQ------------------------------------
--------LCEECFQ---------------M---TEQ---EAIQDL--WQRKSF------
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SLDM-DMSPL----
--RLQN-Y---LFGCEV--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDKLH--IVEAEAMNYEGG-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLQL-KC
GSGPVHIS-GQHLV--------A-VEEDAESKDE-KEEDMKLL-SIS----GKHSAPGSG
-SMF--------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SVDM-DMSPV----
--RPQ-NY---RFGCEL--KADK-DYNFTVDNDEN----EYQLSLRT---VS-LGA--GA
KDELH--IVEAEVINYEGS-PIKVT-LPTVSLGG---------FEITPP-V--VLRL-KC
GSGPMHIS-GQH LE--------AVE-------ED-EEEDVKLL-SIS----GKRSAPGSD
-SKFPQKKVKLAADEDDDDDDE--------------------------------------
---------------------------------DNDDEDDDDDDFDDEEAED-KAPVK--
-KSIQDTPA-KNAQKSR-----QNEKDSKPS-TL-----------RSKGQESFKK--QER
---TPKTPKGPSSV EDIKGKMQASLE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFQ---------------M---TDQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------VEN--STDM-GMSPL----
--RAQ-NC---LFGCEL--KADK-DDHFKVDNDEN----EHQLSSRT---VS-LGT--GA
KDELH--VVEAEATHYEDS-PIKVT-L---KTSIQPSVS-LGGSEITPP-V--VL-G-T-
------------------------------------------L-KHI----WKRICPGNG
-SKFPQKKVKLADE----------------------------------------------
--------------------------------------NDDDENEEVKKSIGE-T-----
-------PV-KNAQKSN-----QNGKDSKAS-TP-----------KSKGHESLQK-----
QEKTPEIVKGPRSVQDIKAKTQ---A-KR-------WFSSKVEPS--------SSI----
------VT--NLFWM---------------T---A-Q---EASQDL--RQWRRSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQN-Y---LFGCEL--KADK-DYHFKVDNDKN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPMVS-LGVFEITPP-V--VLRL-KC
GSGPVHIS-GQHL V--------A-VEEDAESEDE-EEEDVKLL-SMS----GKRSARGGG
-SKVPQKKVKLAADEDDDDD----------------------------------------
--------------------------------------EDDDDDFDDEETEEK-VPVK--
-KSIRDTPV-KNAQKSN-----QNGKDSKPSSTP-----------RSKGQESFKK--QEK
---TPKTPKGPSSV EDIKAKMQASIE-KG-------GSLPKVEAN--------ILI----
------K-----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------TVS-LGGMKI-NP-V--VFCL-KC
GSGPVHIS-GQHLV--------A-VEEDAEKEHE-E-EDVK----------L-RSAPGSG
-SKIPQKQVELAAKENPQP-----------------------------------------
---------------------------------------KMH--------------KS--
-Q-------------TR-----MEKTQSNQY-QN-----------QKKRPESFKKQE---
--KVPKSLKESSSVEDIKAKMQARIG-KG-------GSLMKVEVK--------FIN----
------YM--KKCFW---------------M---TEQ---DAIQDR--W-----------
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-VVSPL----
--RPQ-NN---LFHCEL--KADK-DYHFQVNNDEN----EHQLSLRT---AS-LGA--DA
KDKLH--IVEAETMNYESS-PIKVT-LATLKMSV---------------------QP-TC
GSGPVHIS-GQHLL--------A-VEKDSEAEDE-EQEDVKLL-SIS----GK-----GG
-SKFPQKKVKLAADEED-------------------------------------------
----------------------------------------DDDDFDDEETKEK-APVK--
-KSIQDTPA-KNAQKSN-----QNGKDSKPS-TP-----------RSKGQESFKK--QEK
---IPKTPKRPSSLEDIKAKMQASIQ-KA-------Y-----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQ-NY---LFGCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHLV--------A-VEEDAESEDE-EEEDVKLL-SIS----GKRSAPGGG
-N----------------------------------------------------------
------------------------------------------------------------
------TPT-KNAQKSN-----QNGKDSKTIITP-----------RSKGQDSFKK--QEK
---TPKTPKGPTSVEDIKAKMQASMW-KP-------SSSIM-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-EISPL----
--RSQ-NY---LFSCEL--KADK-DYHFKVDNDEN----EYQLSLRT---VS-LGA--GA
KDELP--IVEAEAMNYEGS-PIKVT-LATENVCTPPRP----------------------
--------------------------------------ALKLL-SIS----GKRSAPGGG
-SKVPQKKVKLAADEDDDDDDE--------------------------------------
---------------------------------DDDDEDDDDDDFDNEEAEE-KAPVK--
-KSIRDTPA-KNAQKSN-----QNGKDSKPSSTL-----------RSKGQESFKK--QEK
---TPKTPKGPSSV EDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFW---------------M---TDQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------KED--SMDM-YMSPL----
--RAQ-NL---L-RCEL--KAEK-DHHFKVTNNEN----EHQLSLRT---IS-LGP--EA
KDELH--IVEAEENAEE-D-DVKLL-S-----------I-SGKKKVK-------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------LADEDDDDEKDDEEMEEK-APVK--
-KSVRETPA-KNAQKSN-----QNGKDKTNT-MK-----------IERSRTLKKN-----
RKKTPKTQKG-PSSEDIKAKMQANLE-KG-------GSLPKVEAK--------FII----
------YV--KNCSM---------------T---D-Q---EAIQDL--WQWRKCP-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------TED--SMDM-DTSPL----
--RPQ-NY---FSGCEL--KADK-DYYFKVDNDEN----EHQISLRT---VS-LGT--GA
KDE-H--IVEAAAMSQEVG-TIKVT-LAMLKMSVQPMIS-LK----------------TC
GRG---------------------------------------------------------
-SNVPQQKVKLAVKKGSS------------------------------------------
---------------------------------------------------------E--
-EIYMRYPI--QKCTKN-----QNGKDSKPP-TP-----------RSKGQESFKN-----
QE-KPKTPKGP--VEDIKAKMQ--IE-KG-------GSLSKVEPK--------FTS----
------YV--KNCFH---------------M---TDQ---KAIQNL--WRQKKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MEN--SVDI-GMSPL----
--RPQ-NY---LFDCEL--KTNK-DNHFKVDNDEN----DHQLSLGL---VN-LAA--ST
KDELN--TIEARAVNYEDS-PIKIT-LATLKMSVQAAVF-LEHFEITPL-V--VLLL-KC
VSGPVHII-AV--------------KEDRDSEDE-EEEDVK------------LSVPGND
-SKFPQKNVKLAADNVDF------------DYE---------------------------
------------------------------------------------------------
----------------------KNGKDSKPS-TL-----------RSKSQESFNE-----
---TPKMLKEP----NIKAKVQIVLI----------------PKS--------SSI----
------YV--KNYFQ---------------M---TDQ---ECIQNP--WPWRKSLQENSL
NGLLKIFH------------L--------------------------ISFL---------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMRP-----
----Q-NY---LFGCEL--KADK-DYHLKVENDEN----EHQLSLRM---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTGS-LGGFEITPP-V--VLRL-KC
GSGPVYIS-GQHLV--------V--EEDAESEDE-EEED--------------RSATGGG
-NKVPQKKGKLAADEDDDEDED---------D----------------------------
---------------------------------DEDDFDDNDDDFDDNEAEEK-APSN--
-Q---------------------NGKD-SKLSTP-----------RSKGQEAFKK--QEK
---TPKTPKGPSSVEDIKAKMQPSLQ-PH-------SFFQRF-SV--------CG-----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------MNDEGS-PIRVT-LATLKMSAQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHL V--------A-VEEDAESEEE-EEEDVKLL-STS----GKRSAPGGG
-SKVPQKKVKLTADEDDEDDED---------E----------------------------
-------------------------------------------EEEDEETEE-KAPVK--
-KSIRDTPA-KYAQKSN-----QNGKDSKP-STP-----------RSKGQESFKK--QEE
GGPSPKTPKGPSSV EDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---PDQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDV-DTSPL----
--RPQ-NY---LFGCEL--KANK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--TVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHLV--------A-VEEDAESEDE-DEEDVKLL-SMS----GKRSTPGGG
-NKVPQKKVKLDEDDDEDDEDD---------E----------------------------
----------------------------------DDEDDDD-DDFDDEEAEE-KVPVE--
-K---------------------------------------------SGQESFKK--QEK
---PPKTPKGPSSVEDIKAKMQTSIE-KA-------H-----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--WPQN-Y---LFGCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPMVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHLV--------A-VEEDAESEDE-EEEDVKLL-SIS----GKRSAPGSG
-SKKAPVK----------------------------------------------------
------------------------------------------------------------
-KSIRDTPA-KNAQKSN-----QNGKDSKPS-TP-----------RTKGQESFKK--QEK
---TPKTPKGPSSVEDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWR--K-----
---------------------------------------SL-------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----MR-P---QTGCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LAALKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHL V--------A-VEEDAESDDE-EEEDVKLL-SIS----GKRSAPGSG
-SKVPQKKVKLAADEDEDEEDED-------------------------------------
---------------------------------EDEDEDDDDDDFDDEETEEK-APVK--
-KSIRDTPA-KNAQKSN-----QNGKDSKPS-IP-----------RSKGQESFKK--QEK
---TPKTPKGPSSV EDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------ILRLHLTED--SMDM-DMSPL----
--RPQ-NN---FYGCEL--KADK-DDHFKVDNDEN----EHH-L----------GS--GA
KDKLH--IVEAEAVNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-RQHL V--------A-VEEDAESDED--EEDVKLL-SMP----GKRSAPGGC
-NKIPEKKLKLDEDDDEDD-----------------------------------------
----------------------------------EDDEDDDDDDFDDEEAEEK-VPVK--
-KSGQESFK-KQG------------------------------------K--------KK
---NPKTPKGPSSI EDIKAKMQASIE-KG-------GPLPKVEAK--------SIS----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRKYL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------MNYEGS-PIKVT-LATLKISVQPMVS-LGGFEIIPP-V--LLRL-KC
GSGPVHIS-GQHL V--------V-VEEDAESEDE-EEEDVKLL-S-------GS------
--RVPQKKVKLAANEDE----E--------------------------------------
-----------------------------------D------DDFDDEEAEE-KAPVK--
-KSIQDISA-INAQKSN-----QNGKDSKA-STP-----------RSKGQESFKK--QEK
---APKTPKGPSSV EDIKAKMQASIE-KG-------GSLPKVEAT--------FIN----
------YV--KNCFW---------------M---IDQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPR----
--RPQ-NY---LFGCEL--KTDK-DYHFKVDNDEN----DHHL-------------GASA
KDELH--IVEAEAMNYKGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL---
-------N-GQHLV--------A-VEEDAESEDE-EEEDVKLL-SMS----GKQSALGGG
-SKVPQKKVKLAAEDDDDE-----------------------------------------
----------------------------------EEDDDDDDDDFDDEETEEK-VPVK--
-KSIHDTSA-KNAQKSN-----QNGKESKPSSTP-----------RSKGQESFEK--QEK
---TPKTPKGP TSI-----------E-KG-------GSLPKVEVK--------FIN----
------YV--KNCFR---------------M---TDQ---KAIQDL--WQWRN------F
N--------------------------------------NLLKIFCLISFL---------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQ-NY---LFGCEL--KANK-DDHFKVDNDEN----EHQLSLRM---VS-LGT--GA
KDELH--IVEEEAMNYKGS-PIKVT-LPKLS---------LGGFEIIPP-A--LLRL-KC
GSGPVHIS-GQHL V--------A-VEEDAESEDE-EEEDVKLL-SIS----GK-------
-HKFPQKKVKLAAIEDD-------------------------------------------
----------------------------------------DDDDFDDEETEE-KAPVK--
-KSIQDTTA-KNAHKSN-----QNGKDSKPSSTP-----------RSKGQESFKK--QEK
---TPKTPKGPSSV EDVKAKMQASIE-RG-------GSLPKVEAK--------FIS----
------YV--KNCFW---------------V---TDQ---EAIQDL--WQWRNLNNLL--
------------------------------------------KIFHLISFP---------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQ-NY---LFGCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHLI--------A-VEEDAESEDE-DEEDVKLL-SMS----GKRSAPGGG
-NKVPQKKVKLDEDDEDD---D---------E----------------------------
---------------------------------DDEDDEDDDDDFDDEEAEE-KVPVK--
-KSVRDTPA-KNAQKSN-----QNGKDLKPST-P-----------RSKGQESFKK--QEK
---TPKTPKGPSSVEDIKAKMQASIE-KA-------H-----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQN-Y---LFGCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHL V--------A-VEEDAESEDE-EEEDVKLL-SIS----GKRSAPGGG
-SKVPQKKVKLAADEDDDDDD---------EE----------------------------
---------------------------------D-DDEDDDDDDFDDEEAEEK-APVK--
-KSIRDTPA-KNAQKSN-----QNGKDSKPSSTP-----------RSKGQESFKK--QEK
---TPKTPKGPSSV EDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--LMDM-DMSPL----
--RPQ-NY---LFNCEL--KVDK-DYHFKFDNDEN----EHQLSLST---VS-LGA--GA
KGDLH--IVKAEPMNYEGS-PIKVT-LATLKMSVQSMVS-IGGFEITPP-L--VLWL-NC
GSGPVHIS-GQHL V--------A-VEENAESEDE-EEEDVKLL-SIS----GK-------
--S---------------------------------------------------------
------------------------------------------------------------
-------KG-QES----------FKKQ-------------------------------KK
---SPITPERPSSVEY IKAKMQASTE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFQ---------------M---TDQ---EAIQYL--WQWWKSLEENSL
N--------------------------------------NLLKIFRLISFL---------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DISPM----
--RPQ-NY---LFSCEL--KADK-DDHFKVDNDEN----EHQLSLRM---VS-LGA--GA
KDELL--IVEAEAMNYEGS-PIKVT-LATLKMSVQPMVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHLV--------A-VEEDAESEDE-EEEDVKLL-SIS----GRQSAPGGG
-SKIPQKRVKLAADEDDDDDE---------------------------------------
-------------------------------------DDDD-DDFDDEEAEE-KAPVK--
-KSIRDTP--------------------AK-NPQ--------------------------
-----------NSIEDIKAKMQASIE-KV-------H-----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQ-ND---LFSCEL--KADK-DYQVKVDNDEN----EHQLSLRT---VS-LGA--GA
EDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEIIPP-V--VLRL-KY
GSGPVHIS-GQHLV--------A-VEEDGESDEE-EEEDVKLL-SIS----GN------G
-SKVPQKKT-------DEDV----------------------------------------
---------------------------------------DDEEDDDDDEAEE-KAPVK--
-KSIQDTPA-KNAQKSN-----QNGKDSKPS-TP-----------RSKGQESFKK--QEK
---TPKTPKGPSSVEDIKAKMQASIE-KI-------ELGSLRLRS--------RRRNH--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQN-Y---LFGCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHL V--------A-VEEDAESEDE-EEEDVKLL-SMS----GKRSAPGGG
-SKVPQKKVKLAADED--------------------------------------------
----------------------------------------DDDNFDDEETEEK-VPVK--
-KSIRDTPA-KNAQKSN-----QNGKDSKPS-TP-----------RSKGQESFKK--QEK
---TPKTPKGPSSV EDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRNLN-----
---------------------------------------NLLKIFRLISFL---------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQN-Y---LFGCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHL V--------A-VEEDAESEDE-EEEDVKLL-SIS----GKRSAPGGG
-SKVPQKKVKLAADEDDDDDD---------ED----------------------------
---------------------------------D-DDEDDDDDDFDDEEAEEK-APVK--
-KSIRDTPA-KNAQKSN-----QNGKDSKPSSTP-----------RSKGQESFKK--QEK
---TPKTPKGPSSV EDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--LMDM-NMSPL----
--RPQ-NY---LFGCEL--KADK-NYQSKVDNDEN----EHQLSLTT---VS-LGA--GA
EDELH--IVEAEATNYKGS-PIKVT-LATLKMSVQPTVS-LGGFKVTPL-V--DLRL-KC
GSGPVHIG-GQH LA----------VEEDAESEDE-EEEDVKLF-TVS----GKRSAPGGG
-IKLAA-------DEDDDE-----------------------------------------
---------------------------------DDDDDDEDDDDSEDEEAKE-KGPVK--
-KSVRDTPA-KNAQKSN-----QNGKDSKPSSTP-----------KSKGQEFFKK--QEK
---TPKTPKGPSSV EDIKAKMQASIE-KG-------GSLRRVGAK--------FIN----
------YV--NNCFW---------------M---IDQ---EAIQDL--WQWRNLNNLL--
------------------------------------------KIFLLILFL---------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQN-Y---LFGCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PVKVT-LATLKMSVQPTVS-LGDFEITPP-V--VLRL-KC
GSGPVHIS-GQHL V--------A-VEEDAESEDE-EEEDVKLL-SVS----GKRSAPGGG
-SKVPQKKVKLAADEDDDDDDEE-------------------------------------
-----------------------------------DDDEDDDDDFDDEEAEEK-APVK--
-KSIRDTPA-RNAEKSN-----QNGKDSKPS-TP-----------RSKGQESFKK--QEK
---TPKTPKGPSSV EDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRNLN-----
---------------------------------------NLLKIFCLISFLLTVDIWLSC
L-----------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-GMSPL----
--RPQN-Y---LFGCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
CSGPVHIS-GQHLV--------A-VEEDAESEDE-EEDDVKLL-SIS----GKRSAPGSG
-SKFPQKKVKLADEDDDDDDED--------------------------------------
---------------------------------EDDDEDDDDDDFDDEEMEEK-APVK--
-KSVRETPA-KNAQKSN-----QNGKDSKPSTPK----------S--KGQESFKK--QEK
---TPKTPKGPSSVEDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------HHPMED--SMDM-DMSPL----
--RPQ-NY---LFGCEL--KTDK-DYHFKVDNDEN----EHQLSLRT---VS-LGT--GA
KDELH--IVEAEAINYEGS-PIKVT-LATLKMSIQPTVS-LGGFEITPP-V--VL-I-EV
GSGPVHI--GQHLV--------A-VEEDAESEDE-EEEDDEET-EEK----DP-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--LTDT-DMSPL----
--RPQ-NY---LFSCKQ--KADK-DYHFKVDNDEN----EHQLSLRT---VS-VGA--SA
KDELH--IVEAEAMNYKGS-PIKVT-LATLKMCVQLTVS-LGGFEITSP-V--VLWL-KC
GSGPVRIS-GQHL V--------A-VEEDAESEDE-EEEDVKLL-SIS----GKESAPGGG
-SKIPQKKVKLAADEDDNDEDD---------E----------------------------
----------------------------------E--------------IEE-K------
----------------------------------------------------------AP
---TSKISKGSSSV EDIKTKIQANIE-KS-------GSLPKVEAK--------FIN----
------YV--KNCFW---------------M---TDQ---VAIQDL--W-----------
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-MKIKINWCESVLSGC---SFEQWSFISVHLLFYLSACCHPLED--SMDM-DMSPL----
--RPQ-NY---LFSCEL--KADK-DYHFKVDNDEN----EHYNT----------------
---------------------------GNLKNVCTANVS-LGGFEIAPP-V--VLQL-KC
GSGPMHIN-GQRL V--------A-VEKDAESEDE--EENVRLL-SVS----GKWSAPGDG
-SKVPQKKVKLAADEDDDGEDD--------------------------------------
---------------------------------------DNDDDFDDEETEEK-VPVK--
-KSIHDTPA-KNAQKSN-----QNGKDSKPSSTP-----------RSKGQESFKK--QEK
---NPKTPKGPTSV EDIRAKMQANIE-KG-------DSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TNQ---EASQDL--WQWRN------L
N--------------------------------------NLLKIFHLISFL---------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQ-NY---LFGCEL--KDDK-DYNFQVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PNKVT-LATLKMSV---------------------QP-TC
GSGPVHIS-GQHLV--------A-IEEDAESEDE-DEEDVKLL-CMS----GKQSAPGGG
-KKV-----KIGEDE-DDDEDE---------D----------------------------
--------------------------------------EDDDDNFDDEEAEEK-VLVK--
-KSARDTPA-KNAQKSN-----QNGKDLKPS-RP-----------RSKGQESFKK--TGK
---TSKTPKGPGSVEDIRAKMQASIE-KA-------HCGERGKGE--------T-N----
------IAHTE-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------MNYEGS-PIKVT-LVTLKMSVQPVVS-LGGFEIIPP-V--LLWL-KC
GSGPVHIS-GQHL V--------V-VEEDAESEDE-EEEGVKLL-S-------GS------
--RVPQKKVKLAANEDE----E---------D----------------------------
-----------------------------------D------DDFDDEEAEE-KAPVK--
-KSIQDISA-INAQKSN-----QNGKHSKA-STP-----------RSKGQESFKN--QEK
---TPKTPKGPSSV EDIKAKMQASIE-KG-------GSLPKVEAT--------FIN----
------YV--KNCFW---------------M---IDQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MEE--SMDM-DMSPL----
--RPQN-Y---LFCCEL--KADK-DYYFKVDIDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEIIPP-V--VLRL-KC
GSGPVHIS-GQHL V--------A-VEEDAESDEE-EEEDVKLL-SIS----GKRSTPGSG
-SKVPQKKAKLAADEDNDDDDDD-------------------------------------
---------------------------------DDDDEDDNDDDFDDEEAEEK-APVK--
-KLIQDTPA-KN-----------NGKDSKPSTP------------RSKGQESFKK--QEK
---TPKTRKGPSSV EDIKAKMQPSIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSHF----
--RSQ-NY---LFCCEL--KAYK-NYHLKMDSQNYLFCCELKLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEIAPP-V--VLWL-RC
GTGPVHIS-GQHLV--------A-VEEDAESEEE-DEKDVKLL-SMS----GKRSAHGGG
-NKIPQEKKVKIDEDE--------------------------------------------
------------------------------------EDDNEDDDFDNEETEEK-VPVK--
-KSVRDTPA-KNAQKSN-----QNGKDL-NLSTP-----------RSKGQESFKK--QEK
---TSKTPKGPSSVEDIKAKIQASIE-KV-------H-----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQN-Y---LFGCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHLV--------A-VEEDAESEDE-EEEDVKLL-SMS----GKRSAPGSG
-SKVPQKKVKLAADEDDDDDEDD-------D-----------------------------
---------------------------------DDDEDDDDDDDFDDEETEEK-APVK--
-KSVRDTPA-KNAQKSN-----QNGKDSKPSTPR----------SKNKGQESFKK--QEK
---TPKTPKGPSSVEDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MEH--SMDM-DMSPL----
--RSQ-ND---LFSCEL--KADK-HYHFKVDNDEN----EHQLSLRT---VS-LRA--GA
KDELH--IVEAEAMNYAGS-PIKVT-LATLKMSVQPTVS-LGGFE-ITP-----------
----------PC----------------GSRP-----VHIS-G-HIS----GKRSAPGGG
-SKVPYKKVKLAADEEDDYDD---------------------------------------
-----------------------------------DNDEDDDDDFDDEETEE-KAPVK--
-KSIRDTPA-KNAQKSN-----QNGKDSKPPSTP-----------RSKGQESFKK--QEK
---TPKTPKGPSSV EDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRKSLQENSL
N--------------------------------------NLLKIFSPISFL---------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------LNG--RLNPLDTSPL----
--RPQ-DH---LFGCEP--KADK--GHFKLDNDEN----EHLLSLRM---VS-LEA--GI
EYELH--TVEAETVNYEGG-AIKVT-LAALKMSVPLAVS-PGGPLKR------HHLL-KC
GSGLVHIS-GKHLV--------A-IEKDREPEDE-EEEDVKLL-----------MMSGSG
-SKIPQKKIKLTAAEDEGRGGGRGKEGRTE------------------------------
----------------------------------VGEEDTFDDE----------------
-VSKEKLQP-KNAQKSK-----QNRKDSKPS-TQ-----------RLKCQDSFKSQEK--
----TPKPEGPSSVDDVKAKMQTSIE-KD-------GSLPKVDAN--------FIN----
------TV--KNCFQ---------------R---TDQ---EAIQNF--WQEWNSSL----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--LMDI-DISPL----
--RPQ-YC---LFSCEL--KASK-DYQFN-DNDAN----EHQLSLRM---VS-LGA--GT
KDELH--IVEPEAMNYKDS-SIKIT-LATFKMSI--TVS-LGGFEIMPP-V--VLRL-KC
GSR---------------------------------------------------SARGSG
-SKLPQKKVKFPNDDDDDDDEEEEE-----------------------------------
-------------------------------------DDEDTEEDKEEEMEEK-APVK--
-KSVRKTPA-KSAQKSN-----QNGKDSKQS-IP-----------NQKIT----------
-GKTPKTLKGPGSVEDIKANMQASIE-KG-------S-----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQ-NY---LFGCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVSL-GGFEITPP-V--VLRL-KC
GSGPVHI T----------------VEEDAESEEE-EEEDVKLL-SIS----GKRSAPGGG
-SKVPQKKVKLTADEDDEDDED---------E----------------------------
---------------------------------DEDDEDDDDDDFDDEETEE-KAPVK--
-KSIRDTPA-KNAQKSN-----QNGKDSKPS-TP-----------RSKVSETREK--GEG
---T------------SLPFMYSFSQ-QG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-GMSLL----
--RPQ-NH---LFSCEL--K---------VDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LAALKMSVQPTVS-LGGFEITPP-V--------C
GSGPVHIS-GQHLV--------A-VEEAA---------------EMS----GKQSTPGGG
-SKSPQKKAKLAADEDEDD-----------------------------------------
-------------------------------------DDFDDDDFDDEEIEEK-VPVK--
-KSIS-----KNAQKSN-----QNGKDSKLSSTP-----------RSKGQESFKKKKQEK
---TPKTPKGPSSVEAIKAKMQVSIE-KA-------H-----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------HY---LAGCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--VIEAEALNYEGS-PIKVT-LASLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHVS-GQHLV--------A-LEEDAVSDDD-EEEEVKLG-NLS----GKRPAPGVV
-PKVPQKKAKLAELAVTDGAHH--------QP----------------------------
---------------------------------NDTLDEDEDDD---FEEEEK-TPAK--
-KSARDTPA-KNAQKSN-----QNGKDSKPS-TP-----------KSKGSESFKKQ-QEK
---SPRTPKGPLTVDDVKAKMQATME-KG-------GALPKVEGK--------FIN----
------YV--KNCFR---------------M---SDQ---EAIQDL--WLWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-MHTEHSWYDSVLRGC---SVGQRWFISVRLLSHRSACRHLIED--AMDV-DMSPP----
--RPQ-NS---LFGCEL--KADK-DDHFKVDNDEN----EHQLCLRT---VS-LGA--GA
KDELY--VVEAEAMNYEGS-PIQVT-LATLKMSAVPTVS-LGGFEITPP-V--VLRL-KR
GSGPVHIS-GQHL V--------A-VEEDAESEDE-EEEDVKLL-SIS----GKRSAPGSG
-SKVPQKKVKLAAAEDDDEDND---------D----------------------------
--------------------------------------EED-DDFDDEEAEE-KAPK---
---SNQNGK-DS---------------KPS-STP-----------RSKGQESFKK--QEK
---IPKTPKRPSSV EDIKAKMQASIE-KG-------GFLRRVEAK--------FIN----
------YV--KNCLC---------------M---TEQ---EAIQDL--WQWRNL------
N--------------------------------------NLLKIFRLISFL---------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--LMDM-DMSPL----
--RAQ-NY---LFGCEL--KADK-NYQSKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFKVTPP-V--VLRL-KC
GSGPVHTS-GQHL V--------A-VEEDAELEDE-EEEDVKLL-SVS----GKRSAPGGG
-GKVPQKKVKLAADEDDDDE-----------D----------------------------
----------------------------------DD-EEDD-DDSEDEEAEE-KVPVK--
-KSSNQNGK-DS---------------KPS-STP-----------RSKGQKFFKK--QEK
---TPKTPKGPSSV EDIKAKMQVSID-KG-------GSLRRVGVK--------FIN----
------YV--KNCFW---------------M---TDQ---EAIQDL--WQWRNL------
N--------------------------------------NLLKIFLLISFL---------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQN-Y---LFGCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAETMNNEGS-TIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHL V--------A-VEEDAESEDE-DEEDVKLL-SMS----GKRSAPGGG
-SKVPQKKVKIDEDEEEDDE-----------D----------------------------
---------------------------------DEDDEDDDDDDFDDEEAEEK-VPVK--
-KSVRDTPA-KNAQKSN-----QNGKDLKPSTPR----------S--KGQESFKK--QEK
---TPKTPKGPSSV EDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DTSPL----
--RPR-TI---Y----------------------S----LHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PMKVT-LATLKMPVQSTVS-LGGFEITPP-V--VLCL-KG
GSGPVYIS-GQHL V--------A-MEEDAESEDE-EDEDVKLL-SIS----GKRSAPGGG
-SKVPQKKVKLAANEDDDGGDN--------------------------------------
-----------------------------------DDEDDDDDDFEW-------------
-------------------------KNSKPS-TP-----------RPKDQESIKN--QEK
---TPKTPKGTNSV EDIQAQMQARIE-KG-------GSLPKVEAK--------FIN----
------DV--KNCSW---------------I---PDQ---EALEDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------CEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHLV--------A-VEEDAESEDE-EEEDVKLL-SIS----GKRSAPGGG
-SKVPQKKVKLAADEDDDDDDED-------------------------------------
----------------------------------DDDEDDDDDDFDDEEAEEK-APVK--
-KSIRDTPA-KNAQKSN-----QNGKDSKPSSTP-----------RSKGQESFKK--QEK
---TPKTPKGPSSVEDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMD-----------
-------------------MTDK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
EDKLH--IVEAEAMNYEGG-PIKVT-LATLKMSVQPTVS-IGGFEISPP-V--VLRL-N-
---------GQHLV--------A-VEEDAESEDE-DEEDVKLL-SMP----GKRSAPGGG
-NKVPQKKVKLDKDDDEDD-----------------------------------------
---------------------------------DDDDDDDDDDDFDDEEAEE-KVPVK--
-KSVPDTPA-KNAQKSN-----QNGKDLKPS-TP-----------RSKGQESLKK--QEK
---TPKTPKGPSSV EDIKAKMQA-----S-------GSLPKVEAK--------LIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQ-NY---LF-------ADK-DYHFKVDNDGN----EHQLSLRM---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSGQPTVSLGG-FEITPP-V--ILWL-RC
GPGPVHI N----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------TPA-KNAQKSN-----QNGKDLKPS-TP-----------RSKGQESFKK--QEK
---TPKTPKGPSSV EDIKAKMQASIE-KG-------GSLPKVESK--------FIN----
------YV--KNCFQ---------------M---TDQ---EAIQDL--WQWRKFL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQN-Y---LFGCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHL V--------A-VEEDAESEDE-EEEDVKLL-SIS----GKRSAPGGG
-SKVPQKKVKLAADEDDDDDD---------EE----------------------------
---------------------------------D-DDEDDDDDDFDDEEAEEK-APVK--
-KSIRDTPA-KNAQKSN-----QNGKDSKPSSTP-----------RSKGQESFKK--QEK
---TPKTPKGPSSV EDIKTKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSLL----
--RPL-NY---LFSCEL--KADK-DDHFKVDNDEN----EHQL--------S-LGA--GA
KDELY--IVEAEAMNYEGS-LIKVT-LAALKMSVQPTVS-LGGFEIPPP-V--VLRL-KC
GSGPVHIS-GQHLV--------A-VEEDAESEDE-EKEDVKLL-RIS----GKWSAPGGG
-SKVPQKKVKLAADEDDDDDDD---------D----------------------------
--------------------------------------NDD-L-DTP---AK-DGQK---
---SNRNGI-DS---------------KPS-STP-----------RSKKQESFKK--QEK
---NPKTPKGPSSVEDIKAKMQVSIE-KG-------GSLPRVEAK--------FIN----
------YV--KNCFR---------------T---TEQ---EAIQDL--WQWRKS------
L-----------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDV-DTSPL----
--SPQ-NY---LFSCEL--KANK-GDHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVEPTVS-LGGFEITLP-V--LLWL-KC
GSGPVHI------I--------T-VEEDAESEDE-EEEDVKLL-SIS----GKWLAPGSG
-SKVPQKKVILAADEDEDDDD---------------------------------------
-------------------------------------DDDDDDDFDEEGT-----EEK--
-KSIRDTPA-KNAHKSN-----QNGKDSKPSSTP-----------RAKGQESFKK--QEK
---TPKTPKGPSSV EDIKAKMQAMEA-RF-------ISYVKNCF----------------
-----------------------------------------WMTDQ--EQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQN-Y---LFGCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VVRL-KC
GSGPVHIS-GQHLV--------A-VEEDAESEDE-EEENVKLL-SIS----GKRSAPGGG
-SKVPQKKVKLAADEDDNED----------------------------------------
------------------------------------DEDDDDDDFDDEEAEEK-APVK--
-KSIRDTPA-KNAQKSN-----QNGKDSKPSSTP-----------RSKGQESFKK--QEK
---TPKTPKGPSSV EDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRNLN-----
---------------------------------------NLLKIFCLISFL---------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------MNYEGS-PIKVT-LATLKMSVQPVVS-LGGFEITPP-V--LLWL-KC
GSGPVHIS-GS-------------------------------------------------
--RVPQKKVKLAVNEDED---E---------D----------------------------
-----------------------------------D------DDFDDEESDE-KAPVK--
-KSIQDTSA-INAQKSN-----QNGKDSKASSTP-----------RSTGQESFKK--QEK
---TPKTPKGLSSV EDIKAKMQASIE-KG-------GSFPKVEAK--------FIN----
------YV--KNCFW---------------M---IDQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSLL----
--RPW-NY---LFSCEL--KTNK-DDHFKVDNDEN----EHQL--------S-LGA--GA
KDEF----------------LIKVT-LAALKMSVQPAVS-LGGFEIPPP-V--VLRL-KC
GSGPVHIS-GQHL V--------A-VEEDAESEDE-EEEDVKLL-SIS----GKWSAPGGG
-SKVPQKKVKLA------------------------------------------------
------------------------------------------------------------
---SNRNGI-DS---------------KPS-STP-----------RSKGQESFKK--QEK
---NPKTPKGPSSV EDIKAKMQASIE-KG-------GSLPRVEAK--------FIN----
------YV--KNCFR---------------T---TEQ---EAIQDL--WQWRKS------
L-----------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQN-Y---LFGCEL--KANK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHL V--------A-VEEDAESEEE-EEEDVKLL-SIS----GKRSAPGGG
-SKVPQKKVKLTADEDDEDDEDE-------DE----------------------------
-----------------------------------DDEDDDDDDFDDEETEEK-APVK--
-KSIRDTPA-KNAQKSN-----QNGKDSKPSTPR----------S--KGQESFKK--QEK
---SPKTPKGPSSV EDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQN-Y---LFGCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHL V--------A-VEEDAESEDE-EEEDVKLL-SIS----GKRSAPGGG
-SKVPQKKVKLAADEDDDDDD-E-------D-----------------------------
---------------------------------------DDDDDFDDEEAEEK-APVK--
-KSIRDTPA-KNAQKSN-----QNGKDSKPSSTP-----------RSKGQESFKK--QEK
---TPKTPKGPSSV EDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRNLN-----
---------------------------------------NLLKIFRLISFL---------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQN-Y---LFGCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHL V--------A-VEEDAESDEE-EEEDVKLL-SIS----GKRSAPGSG
-SKVPQ------------------------------------------------------
---------------------------------------DDDDDFDDEEAEEK-ATVK--
-KSIRDTPA-KNAQKSN-----QNGKDSKPSTPR----------S--KGQESFKK--QEK
---TPKTPKGPSSV EDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------IED--SMDM-DMSPL----
--RPQ-NY---LFGCEL--KADK-DYHFKVDNDEN----EHQ----T---IS-LGA--GA
KNELH--IVEVEAMNYESS-PIKVT-LATLKMSVQPTIS-LGEFEITPP-V--W------
------------------------MEEDAESEDE-EEEDVKLL-SIS----GKRFAPGGG
-SKVPQKKVKLAGEDDEDDD----------------------------------------
--------------------------------------DND-YDFDDEETEE-KAPQ---
----------------------------------------------------------EK
---IPKTPKGPSSV EDIKAKMQESIE-KG-------SSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRKS------
L-----------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DRSPL----
--RTW-NY---LFGCEL--KADK-DYHFK-------------------------------
-DELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEIT-------------
-----------------------------------P-P DVKLL-SIS----GKRSAPGGG
-SKFPQKKVKFAADEDD-------------------------------------------
----------------------------------DNDDDE----FDDEDTEEK-APVK--
-KSVRDTPA-KNAQKSN-----QNGKDSKPS-TP-----------RSKGQESFKK--QEK
---TPKTPKGPSSV EDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------Y---------------------------------EAIQDL--WQWRKSF-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MGD--SMDM-DVRPL----
--RPQ-NY---LFGCEP--KANK-DYLFKVDNDEN----EQQLSLRM---VS-LGA--GA
KNELH--IAEAEAMNYEG--------SPTLKMSVQPTVS-LGGFELTPP-V--VLRL-KC
DSGP-------VHI--------T-VEEDAESDDE-EEEDVKLL-STS----GKRSAPGSG
-SKVPQKKVKLAADEDEDEDDE---------D----------------------------
---------------------------------DDDDEDDDDDDSHDEETEEK-APLK--
-MHKNQSRMEKTQN---------------HQ-RQ-----------DLKAKNPLKN--RKK
---TPKTPNGPSSV EDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDR---EAIQDL--WQWRKSP-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQ-NY---LFSCEL--KADK-DYHFKVDNDEY----EHQLSLRT---VS-LGA--GA
KNELH--IVEAEAMNYEGS-SIKVT-LATLKMSVQPTIS-LGGFEITPP-V--VLRL-KC
GSGPVHI------I--------T-VEEDVESEDE-EEEDVKLL-SIS----GKWSAPGGS
-SKVPQKKVKVAADEDDDEEDD---------D----------------------------
--------------------------------------------EDDEEA--E-EKVK--
-KSIQDTPA-KNAQNSN-----QNGKDSKPSSTP-----------RSKGQEPFKKTEK--
---LLKHQKDLVLQKTLKQKC---------------------------------------
-----------KQV----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MEH--SMDM-DMSPL----
--RTQ-NY---LVSCEL--KADK-DDHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYAGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHL V--------A-VEEDAESEDE-EKEDVKLL-SIS----GKQFAPGGG
-SKFPQKKVKLAADEEDDDDEE---------D----------------------------
----------------------------------NDDED-DDDDFDKEA-EE-KAPVK--
-KSIRDTPA-KNAQKSN-----QNGKDSKPSSAP-----------RSKGQESFKK--QEK
---TPKTPKGPSSV EDIKAKMQASIE-KG-------GSLPKVEAN--------LNN----
------L------LK---------------I---FRP---ISFL----------------
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQ-NY---LFGCEL--KADK-DDHFKVDNDEN----ELQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS PLS------------------
-----------------------------------------SC-GGR----CRRSAPGGG
-SKVPQKKVKLAADEDDDDD----------------------------------------
---------------------------------EDDDEDDDDDDFDDEEAEE-KAPVK--
-KSIRDTPA-KNAQKSN-----QNGKDSKPSSTP-----------RSKGQESFKK--QEK
---TPKTPKGPSSV EDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFQ---------------M---TDQ---EAIQDL--WQWRKSV-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MDM-SLL----
--RPQ-NN---IFSGKL--KADK-DYHFKLDNDEN----EHH--LRM---VS-LGA--A-
-----------EAMNYEGS-PIKVT-LATLKMSLES-AS-LEGFEIIPP-VPVALWL-KC
GSGPVHIS-GQHL V--------A-VEEDAESEDE-------------------CSAPGGG
-SKFPLKKVKLAADEDDED-----------------------------------------
---------------------------------------DDFDDEKAE----K-NL----
---------------------------------------------QSKSQESFKKQE---
--KNLLKH-----------QKNLQ AEKNC-------CSPPKVEAK--------F-N----
------YV--KNCFQ---------------M---TDQ---KSL-----------------
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DISPL----
--RPQ-NY---LFG---------------VDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LVTLKMSVKPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHL V--------A-VEEDAESEDE-DEEDVKLL-SVS----GKRSAPGGG
-NKVPQKKVKLDEDDEDDDEDD---------E----------------------------
----------------------------------DD--EDD-DDFDDEEAEE-KVPVK--
-KSV-DTPA-KNAQKSN-----QNGKDLKP-STP-----------RSKGQESFKK--QEK
---TPKTPKGPSSV EDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRKS------
L-----------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--STDM-DMSPL----
--RPQN-Y---LFGCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHL V--------A-VEEDAESEDE-EEEDVKLL-SIS----GKRSAPGGG
-SKVPQKKVKLADED-DDDDD---------ED----------------------------
---------------------------------D-DDEDDDDDDFDDEEAEEK-APVK--
-KSIRDTPA-KNAQKSN-----QNGKDSKPSSTP-----------RSKGQESFKK--QEK
---TPKTPKGPSSV EDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQ-NY---LFN-----------DHFKVDNDED----KHQLSLRM---VS-LGA--GA
KDELH--TVEAEAMNYKGS-PIKVT-LATLKMSIQPMVS-LGGFEITPP-V---------
---------GQHLV--------A-VEEDARK-DE-EEEDVKLL-SVS----GKRSAPGGG
-SKVPQKKVKLAADEDDDYEDD---------D----------------------------
----------------------------------D-DEDDDNDDFDDKETKE-KAPVK--
-QSIRDTPA-KNAQKSN-----QNGKDSKPSSTP-----------RSKGQESFKK--QEK
---TPKIPKGPSSV EDVKANMQARIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--------------
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------MNYKSS-PIKVT-LATLKMSVQPTVS-LVGFEIPPP-V--VLQL-KC
GSGPVH------II--------A-VEEDAESEDE-EEEDVKLL-SMS----GKSSAPGGG
-SKVPQKKVKLAAAEDDDEDDN---------D----------------------------
-----------------------------------D-------DFDEEETEE-KVPVK--
-KSIRDTPA-KNAQKSN-----QNGKDSKPSSTP-----------KSKGQESFKK--QEK
---TPKTPKGPSSV EDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIEDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RSQ-NY---LFSCKL--KAE--HYHFKVDNDEN----EHQLSLRM---VI-LEA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LETLKMSVQPTVS-LGSFEITPP-V--VLRL-MC
GSGPVHIS-GQH LE-------------DAESDEE-EEEDVKLL-SIY----GKQSAPGSD
-SKVPQKKVKLAADEDDEDDDD---------D----------------------------
----------------------------------D--------F----------------
--------------DDA-----ENGKDSKPS-TS-----------RSKGQESFKK--QEK
---TPKTPEGPRSI EDIKAKMQASIE-KC-------DSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------EDS-PIKVT-LATLKMSEWFSLE-------PTH-G--LR-L-KY
GSGPLPIS-GQHLV--------A-LEEDAESEDE-EEEDVKLL-SL---------H-GSG
SRF-PHKKVNLAA-------------------DE-DDE----------------------
--------------------------------DDDDDNDYDDDDFDDEESEEK-SSIK--
-NFVRDTPA-KNARKSN-----KNGKDSKLS-TP-----------RSKAQESFKK-----
QEKTPQTPKGQNSVEDIKD----NIE-KG-------GFLPKVEAK--------FIN----
------YV--KNCFQ---------------F---L------KLKDI--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------IED--AMDV-DMSPP----
--RPQ-NS---LFGCEL--KADK-DDHFKVDNDEN----EHQLCLRT---VS-LGA--GA
KDELY--IVEAEAMNYEGS-PIQVT-LATLKMSAVPTVS-LGGFEIPPP-V--VLRL-KC
GSGPVHIS-GQHL V--------A-VEEDAESEDE--EEDVKLL-SIS----GKRSAPGSG
-SKVPQKKVKLAAAEDDDEDND---------D----------------------------
--------------------------------------EED-EDFDDEEAEE-KAPK---
---SNQNGK-DS---------------KPS-STP-----------RSKGQESFKK--QEK
---IPKTPKRPSSV EDIKAKMQASIE-KG-------GFLRRVEAK--------FIN----
------YV--KNCFR---------------T---TEQ---EAIQDL--WQWRNS------
N--------------------------------------NLLKIFRLISFL---------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------GCEL--KADK-EFQFKVDDEEN----EHQLSLRTASSVT-LGA--GA
KDELH--IVEAEALDYEGN-PTKVV-LASLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVYVS-GQHLV--------A-LEEEPESDEE-DDD-TKIV-NAS----TKRPASGGG
-PKTPQKKPKLAEDDEDDDE--DDDD-------D--DE----------------------
--------------------------------------DDLEDDEEEIKA-----PVK--
-KPVREVAG-KNMQKAK-----QNGKDSKPS-TP-----------ASKSKTPDSK-K--D
KTLTPKTPKVPLSLEEIKAKMQASVD-KG-------TTLPKLEPK--------FAN----
------YV--KNCFR---------------T---EDQ---KVIQAL--WQWRQTL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQ-NY---LFGCEL--KADK-DYHFNVDHDET----EHQLSLRT---VS-LEA--GA
KDELH--IVEAEAMNYEGS-PTKVT-LATLKMSVQPTVS-LGGFEITSP-V--VLRL-KC
GSGPVHIS-GQHL V--------T-VEEDAESEDE-EEENVELL-SVS----GN-------
--KVPQKKVKLAADEDV-------------------------------------------
----------------------------------DDDEEDD-DDFDEEEIEE-KAPVK--
-KSVRDTPA-KNAQKSN-----QNGKDSKP-PTP-----------RSKAQESLKK--QEK
---IPKTPKGPSSV EDIKAKVQGSRE-KG-------GSLPKVEDK--------FVN----
------YV--KKCFR---------------M---TDQ---EAIQDL--WQWRKS------
L-----------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQ-NY---LFGCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTXXXXXXXXXXXX-X--XX---XX
XXXXXXXX-XXXXX--------XXVEEDAESDDE-EDEDVKLL-SIS----GKRSAPAGG
-NKVPQKKVKLAADEDDEDDDD---------D----------------------------
---------------------------------DDDDEEDDDDDFDDEETEE-KVPVK--
-KSVRDTPA-KNAQKSN-----QNGKDSKP--TP-----------RSKGQESSRK--QEK
----TKTPKGPSSVEDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------F---LAGCEL--KADK-EFQFKVDDEEN----EHQLSLRT---VT-LGA--GA
KDELH--IVEAEALDYEGN-PTKVV-LASLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVYVS-GQHLV--------A-LEEEPESDEE-EED-AKIV-NAS----AKRPASGGG
-NKTPQKKPKLAEDDEDDDEDEDDDD-------D--DE----------------------
--------------------------------------DDLEDDEEEIKA-----PIK--
-KPVREVAG-KNMQKAK-----QNGKDSKPS-TP-----------ASKSKTPDSK-K--D
KTLSPKTPKVPLSLEEIKAKMQASVD-KG-------TTLPKLEPK--------FAN----
------YV--KNCFR---------------T---EDQ---KVIQAL--WQWRQSLAET--
---------DL-------QQI--------------------LKLRRAGSPL---------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------RT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-SIKVT-LETLKISRKMQ-----------------------
------------------------------SEDE-EQDNVKLL-NIS----G-KSVPGGG
-SKLPQKKVKLAVDEDEDD-----------------------------------------
---------------------------------------DDDDDDFDECGRKA-STKI--
-S--------------------------------------------NSKPSTPRSKG---
--KTPKTLKGLCSIEDIKAKMQASIEKKN-------GSLPKVEAK--------FIN----
------YV--KNCFQ---------------M---TDQ---EAIQDL--WQWKKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------MNYEGS-PIKET-LATLKMSVQPTVS-LGGFEITAP-V--VVRL-KC
GSGSVHIS-GQHL V--------A-VEEDAESDEE-EEEDVKLL-SIS----GKRSAPGSG
-K------VKLAADDDND------------------------------------------
------------------------------------------NDDDDEEAEE-KAPVK--
-KSIRDTPA-KNAQKSN-----QNGKDSKP-STP-----------RSKGQESSPK--QEK
---TPKTPKGRSSV EDIKAKMQASIE-KS-------GSLPKVETK--------FIN----
------YV--KNCFW---------------M---TDQ---EAIRDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------R--KAHK-DYHFKVDNDKN----EHQLSLRM---AS-LGA--GA
KDELH--TVEAQAMNYEAS-PIKVT-LATLKMPLQPTGS-LGGFEMTPP-V--VLRL-KC
GSGPVHLS-GQH LA--------A-VEEDAESDEE-EEEDVKPL-GIH----GKRSAPGSG
-SKDPQKKVKLAAEEDDDDE----------------------------------------
-------------------------------------DDDDNDDFDDEETGEK-APVK--
-HP--------------------------------------------------SK--RKQ
---TPKTPKGPRSV EDIKAKMQASIE-KG-------GSLCKMEAK--------F------
----ANYV--KHCFR---------------M---TDQ---EAVQDL--WQWRKPL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------KRRDA--AFH---RQPT----
--R-P-VS---LAGCEL--KADK-DFHFKVDDEEN----EHQLSLRT---VS-LGA--GV
KDELH--VIEAEALDYEGN-PIKVT-LASLKMSVQPTVS-LGGFEITPP-V--VLRL-KS
GSGPVYVS-GQHLV--------A-LEEEPESEDE-DDE-VKIL-NTS----SKRPASGIA
-AKTPQKKAKLSEDDDDDDEDDEDEDD------E--DD----------------------
--------------------------------------DDDDLDEEEEKI-----PVK--
-KPAKDLSA-KNTPKSK-----QNGKDSKPS-TP-----------APKSKTPASN-KKEN
KPQTPKSPKVPLSLEEIKAKMQATLE-KG-------SALPKLEAK--------FVN----
------YV--KNCFR---------------T---QDQ---KVIQAL--WQWRQTLRDS--
---------TL-------ASF--------------------YYFDKVLSFI---------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQ-NY---LFGGEL--KANK-DDHFKVDNDEN----EHQLSLRT---VS-LGT--GA
KDELH--IVEEEAMNYKGS-PIKVT-LATLKMSVQPKLS-LGGFEITPT-V--LLQL-KC
DSGPVHIS-GQHL V--------A-VEEDAESEDE-EEENVKLL-SIS----GKQLV----
---------KLAADED--------------------------------------------
--------------------------------------DDDDDF-DDEETEE-KAPVK--
-KSIQDTTA-KNAHKSN-----QNGKYSKPSSTP-----------RSKGQESFKK--QEK
---TPKTPKGPSSV EDVKAKMQASIE-KG-------GSLPKVEAK--------FIS----
------HV--KNCFW---------------V---TDQ---EAIQDL--WHLNN-------
----------------------------------------LLKIFHLISFP---------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SVDM-DMSPL----
--RPQN-Y---LFGCEL--KADR-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVETEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHLV--------A-VEEDAESEEE-EEEEVKLL-SIS----GKRSAPGSG
-SKVPQKKVKLAADEDDD----D-------DD----------------------------
---------------------------------NDDEEDDDDDDFD-EEVEEK-APVK--
-KSVRDTPA-KNAQKSN-----QNGKDSKPSTPR----------S--KGQESFKK--QEK
---TPKTPKGPSSVEDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRKSL-----
---------------------------------------LLKIFRLIS--F--------L
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--AIDV-DMSHL----
--RPQ--Y---LFGCEL--MANK-DYHFKVDHAKN----GHQLSLGT---V---------
----------SRSMNYEGS-PIKVT-LATQKMSVQPMVS-LGGFEITPP-M--VLTVEVC
GSGPVRTS-GQHLV--------A-VQEDAESEDE-EED------GMS----EKPSVPGGG
-NKAPQKKVRLAADEDDDDD----A-----------------------------------
-------------------------------------DGD--DEEEEEETEEK-APVK--
-KSVQATTA-KHAQKSN-----QSRKHSKPS-TP-----------GGTCGSKANKQTK--
QERIIKKPKGPGSIEDIKAKMQEDLE-KS-------GSLPKV-----EPN---FIN----
------YV--KK------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--AMDV-DMSPP----
--RPQ-NS---LFGCEL--KADK-DDHFKVDNDEN----EHQLCLRT---VS-LGA--GA
EDELY--VVEAEAMNYEGS-PNQVT-LATLKMSA-PTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHL V--------A-VEEDAESEDE-EEEDVKLL-SIS----GKRSAPGSG
-SKVPQKKVKLAAAEDDDEDND---------D----------------------------
--------------------------------------EED-DDSDDEEAEE-KAPK---
---SNQNGK-DS---------------KPS-STP-----------RSKGQESFKK--QEK
---IPKTPKRPSSV EDIKAKMQASIE-KG-------GFLRRVEAK--------FIN----
------YV--KNCFR---------------T---TER---EAIQDL--WQWRKS------
L-----------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MGD--SMDM-DLSPL----
--RPQN-Y---LFSCEL--KADK-DDHFKVDNDEN----EHQLSLRM---VN-LGA--GA
KDELH--IVEAEETNYKGS-PIKVT-LANLKMSVQPTVS-LGGFEIPPP-V--VLRL-KC
GSGPVHIS-GQHL V--------A-VEEDAESEDE-EEEDVKVL-SIS----GKRSALGDG
-SKVPQKKVKLAADEDDDDDE---------------------------------------
-------------------------------------DDDDDDDFDDEEAEEK-APVK--
-KSIRDTPA-KNAQKSN-----QNGKDSKLSSTP-----------RSKGQESFKK--QEK
---TPKTPKGPN----IKAKMQASIE-KG-------GCLPKVEAK--------FIN----
------YV--KNCFW---------------M---TDQ---EAIQDL--WQWRNLN-----
---------------------------------------NLLKIFHLISFL---------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------LEN--SMDL-DKTPL----
--WSQ-KY---LFGCEP--KAHK-DYHLKVDNDEN----EHHLSLRR---IS-LGA--GA
KERLH--TVEAKVMNYKGS-PIKVT-LATLKMSVQPTVS-LG-FEITPP-V--VLQL-KC
GSGPVHIS-GHLVA--------V--EEDTESEKD----EKELL-SIS----EKSSVP---
-----GSGSKVPKKKVKP-------------AA---------------------------
-------------------------------------NEDDDDDFDDEKAK------K--
-RSQILQPK--IVQKSI-----QNAKESKAS-TP-----------RSKN--LE-------
--KTPKTLKGSCSTENIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YR--IV------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQN-Y---LFGCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHL V--------A-VEEDAESEDE-EEEDVKLL-SIS----GKRSAPGGG
-SKVPQKKVKLAADEDDDDDD---------ED----------------------------
---------------------------------D-DDEDDDDDDFDDEEAEEK-APVK--
-KSIRDTPA-KNAQKSN-----QNGKDSKPSSTP-----------RSKGQESFKK--QEK
---TPKTPKGPSSV EDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQN-Y---LFGCEL--KADR-DYHFKVDNDEN----EHQLCLRT---VS-LGA--GA
KDELH--VVEAEAMNYEGS-PIKVT-LATLEMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHLV--------A-VEEDAESKEE-EEEEVKLL-SIS----GKRSAPGSG
-SKVPQKKVKLAADGDEDDDDDD-------------------------------------
---------------------------------DDDEDD----DDFDEEVEEK-APVK--
-KSVQDTPA-KNAQKSN-----QNGKDSKPS-TP-----------RSKGQESFKK--QEK
---TPKTLKGPSSVEDIKAKMQASIE-KR-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWR--K-----
---------------------------------------SL-------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQN-Y---LFGCEL--KADK-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHLV--------A-VEEDAESEDE-EEEDVKLL-SIS----GKRSAPGSG
-SKVPQKKVKLAADEDEDDDDDD-------------------------------------
---------------------------------DDDDEXXXXXXXXXXXXXXX-XXXX--
-XSVRDTPA-KNAQKSN-----QNGKDSKPS-TP-----------RSKGQESFKK--QEK
---TPKTPKGPSSVEDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWR--K-----
---------------------------------------SL-------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQ-NY---LFGCEL--KADK-DDHFKVDNDKN----KHQLSLRT---VS-LGA--GA
KDELH--VVEAEAMNYEGS-PIKVT-LATLKMSVQP--------MVSLG-V--VLRL-KC
GSGLVHIS-GQHLV--------A-VEEDAESEDE-EEEDVKHL-SIS----GKRSATGGG
-SKVPQKKVKLAADEDDDDDD---------------------------------------
--------------------------------------DDDDDDFDDEEAEEK-APVK--
-KSIRDTPA-KNAEKSN-----QNGKDSKASSTP-----------RSKGQESFKKN-RKK
---TPKTPKGPSSVEDIKAKMQASVE-KS-------SSFISIPFS--------DLP----
------PM----PLQ---------------A---GNN---LTLGSL--KHFLLTAVVQ--
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQN-Y---LFGCEL--KADR-DYHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--VVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHLV--------A-VEEDAESEEE-EEEEVKLL-SIS----GKRSAPGSG
-SKVPQKKVKLAADEDEDDDDDD-------D-----------------------------
---------------------------------DDDDEDDDDDDFD-EEVEEK-APVK--
-KSVRDTPA-KNAQKSN-----QNGKDSKPSTPR----------S--KGQESFKK--QEK
---TPKTPKGPSSVEDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRKSL-----
------------------------------------------------------------
------------------------------------------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MED--SMDM-DMSPL----
--RPQN-Y---LFGCEL--KADK-DDHFKVDNDEN----EHQLSLRT---VS-LGA--GA
KDELH--IVEAEAMNYEGS-PIKVT-LATLKMSVQPTVS-LGGFEITPP-V--VLRL-KC
GSGPVHIS-GQHL V--------A-VEEDAESEDE-EEEDVKLL-SIS----GKRSAPGGG
-SKVPQKKVKLAADEDDDDDD-D-------ED----------------------------
---------------------------------D-DDEDDDDDDFDDEEAEEK-APVK--
-KSIRDTPA-KNAQKSN-----QNGKDSKPSSTP-----------RSKGQESFKK--QEK
---TPKTPKGPSSV EDIKAKMQASIE-KG-------GSLPKVEAK--------FIN----
------YV--KNCFR---------------M---TDQ---EAIQDL--WQWRNLN-----
---------------------------------------NLLKIFRLISFL---------
------------------------------------------------------------
-------------------

Query Results

"ENSGT00440000034554_2"

ENSGT00440000034554_2