ENSGT00440000033468_1 : Linker Region Query Results

------------------------------------------------------------
------------------------------------------------------------
--------------MPGEAARAELLLPEADGPGPRTDLSCDAAAATTILGGDR------R
EPCALT-PGPSHLALTFLPSKPGARPQPEGASWDAGPGGAPSAWANPGEGGPSPMLLPEG
LSSQALSTEAPLPATLEPRIVMGEETCQA-LLSP---------------RAARTALRDRE
G-GHASPDPPPELCSQGDLSVPSPPPDPDSFFTPPSTPTKTTYALLPGCGPLGDAG--DS
EAELWDELLDSPPPSPSGSYITADGDSWAS------SPSCSLSLLAPAEGLDFPSGWGLS
PQGSMA--------------DERELHPAGTPEPPSSESSLSADSSSSWGQE---SHFFDL
DFLANDPMIPAALLPFQGSLIFQVEAVEVTPLSPEEE-EE----------AVVDPDPGGD
-LAGEGEEDSTSASFLQSLSDLSITEGMDEAFAFRDDTSAASSDS--DSASYAEADD-ER
LYSGEPHAQAT-LLQDSVQKTEEESGGGAKGLQVQEG---------TMCWALE-----AA
PQTPDRGAH-LSQRRESIS-----EVTEEGLALGQESTATVTPHTLQ-------------
------------------------------------------------------------
--------------VAPGLQVEAATRVTPQAGEEKADSTTGQASAAMAM-----PQPSQE
GISEILGQESVTA--EKLPTPQE--------------------ETSLTLCPDSPQNLKEE
GG-------------------------------------LDLPSGPKP-IAAASLMPQQA
EEDLTLPQDPA-VTPPLPLQDMDLSSAPKPVAASHDVP----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------SRRRKTSPYPEAS-LEPLCPT-RHE-LHARQPVG------QPRL-AQQAQEDP
PY-PRTPLYT------LPTD---TD-F-----------RHPEPVEQPLG--TTSQ-DPR-
------------DT----------PLP---------------------------------
-----------------------------------------------------------Y
KTDS----------------RQPEAC--------------------------G---GSTI
SQAAKGHL------------------------------------T---------------
---------------------------------------------------------PGP
AVYTPRP---TYVSVSPKPVAQPRLS--QALN----ELPVP-------------------
---------------------------------------------------RPHINHLPT
SQIFA--------A----------------------------------------------
----------------------------------------RA--------------VSAL
GPTLPGPRCDTTSAPTRHRSRSP----------------------------RAVAQPC--
--C---------------------------------------------------------
------------PQAAD--GS----------SP------------YPRALTPPLPQG---
------------------------LPAWP-------------------------------
-----------------------------------------------------A------
----GEEDPTLPQDSAMTPPLPLQDTGPTSGL-------EPLAVATP-QTLQAEAGCTP-
--------GTEPVATMAQ-------------QE--VGAALGPRPAPEEKNAALSR-----
----------------VPEPAALDQVQQDDPQPA-------------AEAGTPWAAQEDA
DS----------------TLGMEALCLPEPASGAGKEVAEALS-RPGWEACLEALVHTSD
GAKPDSPQKETLEVENQQGGGLKPPAQEHG-P-----GSTLGG-----------------
--AGE-----VPEAPPGACPEVSQAWLLSPAREGRGLSGKSTLEPTLPSAVATEASLDSC
PESSVG----AVSRLDRGCP-DAPAPTSAPTSQQPE------------------------
------------------------------------------------------------
-----------------------------------------------PPVLGLGSVERPH
KAPSVLGPLLLQPPENLGKGLPSASPDRPLG----PD--LSAPGTLAGAALPPLEPPAPC
LCQDLQKDSVEEEEPPGSLGLPTPQAGAQPAA---AAVSGTTQPLGTGPRVSLLPHSPLL
SPKVASM---DAKDLALQISPPCQVPPPSGPQSPAG------------------------
-----------------PQGLSAPEQQEDEDSLEE-------------------------
---------------------------------------------------------DSP
RALGSGQHSD--S-HGESSAELDEQDILAPQ--TAQCPAQA----PAGSSEETIAKAKQS
RSEKKARKAMSKLGLRQ--IQGVT----RITIQKSKNILFVIAKPDVFKSPASDTYVVFG
EAKIEDLSQQVHKAAAEKFKVPSEPSALVPESAPRPRVRLECKEEE--E--EEEEEVDEA
GLELRDIELVMAQANVSRAKAVRALRDNHSDIVNAIMELTM-------------------
----------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------MSFSVSTDLSYDAAAAT-ILKGDQ------R
ESQALA-PGPSPLTLTFLPSKPGARPQPEGASWDAGPGGAAASWADPAEGSPSPVLLSEG
LPLQPLPAEAPLPATLEPRIVMGEETCQA-IPSP---------------RAAWPVLRDGE
G-GHIDLYPPPQLCSQGEPPVPSPPQDLDSYFTPPSTPTETTYALFPDHEPHRDAW--DL
EAELLDELLDSAPASPSGSYITADGDSWAS------SPSCSLSLLAPAEGLDFPSDWGLS
PAGSVT--------------DDQEPHQTAPPELSSSESSLSADSTSSWSQE---GHFFDM
NFLANDPMIPAALLPFRGSLIFQVEAVEVTPLSQEEEKEEE---ED---VAAEASTPAGD
-LGGEG-DDSTSASFLQSLSDLSIIEGMDEAFAFRDDTSAASSDS--DSASYAGADD-DR
LYSGEPHAQSSALIQDSAQKTEQEHR---------DG---------AVFWGTV-----VT
PWVSEQETY-LTNSQESVA-----DMSKEALTAGIEAEATVTPPNLQ-------------
------------------------------------------------------------
--------------AAPDSQVEEVTRVTPWIGVKKVDTTVRKA-------FRALPQPSQK
GISTTLGCESASAES----------------------LLDPQEEISPTLCPVHPKNLKKG
Y--------------------------------------WGLPSALDP-VAVTSIGSQQA
EGGVTVSQDSP-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------VASPPLQGADPTSDPESVT------VATLGHQQAEGDV
TV-SQDFPMA------SSPPLQSSH-P----------TSDPEPGAVATL--GFQL-IEE-
------------DVTVPQDTHMVS------------------------------------
--------------------------PLQKGSDPTSDPEPGIEAT--L-ESQEAKGCIIL
AQD---------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------------T
PMLSLLSLQGSDPTSDQELGAAATLQSQQAEE----DITVPQDSPMVSPP--PQKGSDST
SDPEPGIEATRES--PE-------------------------------------------
------------------------------------------------ANIVP-------
-------------------------------------------------------QDTPM
VSLLPLQGSDPTSEQELRAVATLKYQK---------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----AEGDVTAPQNVPMALPPSLQDTDST-------SDTELIAKNVP-QALQVKTGCTP-
--------GTKPWDCMAQ-------------QE--LGVASEPRPVPEVQDAVPHG-----
----------------DSEQPASNQAQQDGTERAIEAPK---------------------
--------------EGGLTLGME---TPEPASGMEEEVAEGLS-ASKK----EASLEAHN
GVKTHSPQKKALGTKNQRGGGPKSPRQGSR-P-----SIL--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------ARQAQSLPGPAAPC
LCPIPGKASVEDEEPSASCGLLPPQAEAQGVATTTIATSGSTKPLGARRRVSLSTHSS-L
NPKVTPT---DAKDLACLISSPCQVPPPSGTQNPPG------------------------
-----------------PQGLLAPEQQEDEDSLEED------------------------
----------------------------------------------------------SQ
QAPGSDQHSE--S-HGESSAELDEQDISAPQ--TVQCSAQG----PAGSNEETIAKAKQS
RSEKKARKAMSKLGLRQ--IQGVT----RITIQKSKNILFVIAKPDVFKSPASDTYVVFG
EAKIEDLSQQVHKAAAEKFKVPSESSALVPELALGSRVRPECEEQE--EE-EEEEEVEEA
GLELRDIELVMAQANVSRAKAVRALRDNHSDIVNAIMELTM-------------------
----------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------PFQGSLIFQVDAVEVLLLPTPEEE--------------KAPGSAGD
-LSGEGEEDSTSASFLQSLSDTSIIEGVDEAFAFRDDTSAASSDSD--SASYAGADD-ER
LYSGEPHAQPSTLLQDSRCKVEE----RQEDWAPSLGQQE-----P--------------
--------MPVVS-------------------------------------------K---
-----GEVVEIMATQ---------------------------------------------
----------------VPCGQEAATAVIPHN-----------------------------
----------------------------------------WQAEAGP-------------
-----------GQEDAARVTPP--------------------------------------
-------------------LLPEEGLTLGEVSMAAPLTLQEEV-----------------
------------------------------------------------------------
----------------------SATLGHETT-AT------------EMPQTLKEE-----
------VSLVPCPDSL-AMS----------------------------------------
------------------------------------------------------------
-----------------VTLQNEKEEVGP---------GL--------------------
-------TSGRGSVATATP-------------------VPLYEGCILCQESVSMTTP---
-----------------------------V-----TLQRK-------------------A
SLTLHRE-------------SVSM-----ATPL--PL-----QKAAALPLGQEPVAMATP
QALQEEV---------------------------------------------------GC
PLGTAPAASEAA------------------------------------------------
--------------------------LAQPEVGAALGLMSASELVAVAK-----PST---
--TEP----------------------------------------------------EAE
PVALDQ----------------TQQD-------GVGPALDLEPVPETVTP----------
MASGKDADLTSEPVPGRGKGQEAARGLSGPE----------------PGTGSGLQHT---
-------------DD---GAGGLESQGDEGLPARTSGSGKA--------LGS--------
-----------------------------------------SSWMVDLAISPELCQK---
--REP--GL----------------PAAMA----------------SEAGLDSSPEPSAG
AVLGPSGRGCPGEPMSATTPPAPSWVP---ELGA--GAGLQA--------LQPHLGMEEQ
AQA---------------ASTHLSHSPCQSQ-GPY----------------------AQE
LPTEVLD------------RSQLTEAHDR-------------------------------
-------SPPAEDHDTSP--PSEAHDRSPPSEAQDTSPP------SDDHDTSLPS-DDHD
TSLPS-----------D---D-HDMSLPSEARE------TSPP--SK---------AHGT
SPPSEAHD----------------TSPPSHDH----------------------------
DTSPSS--EDH----DTSP--P----TEA------WDTSPPSEAHDTTSQYPDASLP--G
FLAGAAPIPCLCQGFREDCRDKGPPGLPGLQ--------Q------LG------------
-----TDAPPAAAAVSGNPVPPGAG-----------------------------------
------------------------------------------------------------
------------------------------------------------------------
------QQAGLSCPSPPLS------PKA------APMGGPHAKALA--------------
------------------------------------------------------------
----------------AHICAPCQVPPCSGLCPPAS------------------------
-----------------PLGLSAPEQQEDQDSLEEGKGEERGGPHTPGG-----------
------------------------------------------------VDSYSASSPDSF
RAPGSGQHSD--SHAESSAPEMEEQDLAAPR--TSRCPPQA---PTVGSSEETIAKAKQS
RSEKKARKAMSKLGLRQ--IQGVT----RITIQKSKNILFVISKPDVFKSPASDTYVVFG
EAKIEDLSQQVHKAAAEKFKVPAEPSASASESAPGLRATPECAVGCSRAQPRVAQQVDET
GLELRDIELVMAQANVSRAKAVRALRDNHSDIVNAIMELTM-------------------
----------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
--------------SEGEEGGRGLLRPEAGGPGPRTDLSCDAAEAT-TPKGDR------L
EHCALT-SGPSALALTFLHGKPGARPPPEGASWDAGPGRAPSAWAVQAEGGPSPG-----
-PAEVRPAEGPLPASLEPRIVMGEETCQA-APLP---------------RATMPELRDWE
G-GHANLNPPPELCSQGDPPVPFPAPDSDSYFTPPSTPTKTASTLLPGPGPHRDTQ--DA
QAE----LGDSPPASPTGSYITADGDSWAS------SPSCSLSLQALAEGLDVPSGWGFS
PPGSVV--------------DERELPPAGTPDSSSPESSLSADSSSSWGQE---GHFFEL
DFLANDPMIPAYLLPFQGSLIFQVEAVEVTPLPHEEEEVEEE-EQE---EEQEVPLPRGD
-LAGEGEDDSTFASSLQSLSDLSITEGVDEAFAFRDDTSAASSDP--DSASYTGADD-ER
LYSGEPHAGEADLNCL----QTLK----------------------E-------------
-DTGQGFAT--ATSPEPQP-----EVDPA------------AL-----------------
------------------------------------------------------------
---P------------PLQ-----DAGIP--WVQESASETSLEPQLEEEGLTASSPLQDA
GLPLVQESA-----SEASPEPQS--------------------------------EEEDL
TASSTSQDAGL-----------------------PLVQDAGLPLVQGS-VSEVSPEPQSE
E----------DLTASLPLKDEGLPLVQGSASEASLEPQSEEEDLT-ASLSLKDAGLPLV
QRSASEASLEP------------QSEEE--------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------------DLIW-
--SRDLPPRPA-------------------------------------------------
----------LS-PKEEVTVSPPLQVAGLPLV----------------------------
-----------QGSVSE--ASPEPQSEEE-------------------------------
------------------------------------------------------------
ELTASSHLQDAGLPSVQGSVSEASPEPQSEEE----ELTASSHLQDAGLP--SVQGSASD
ASSEPQSEE-DLTACPTLQDTGLPLVQGSAS-------------------KDAGLPLVPG
SASDASSEPQSEEEELTASSHLQ-------------------------------------
----------------------------------DAGLPLVQG--S--------------
------------------------------------------------------------
--------------ASSPPLQDAGLPLVPGSASDAS--SEPQSEEEELTASPTLQDAGLP
LVPGSASDASSEPQSEEDLTACPTLQDTGLPLVQGS------------------------
---------------------------------------------------------ASK
VSPEP----------------QSDLTAS------------PTLQDAGLPLVQGSA-----
----SKASPEPQSEEDLTAFPPLQEAGLPSSQVSAT-------SASP-QAPMTDTGCIQ-
--------ETEPTATAAH-------------RK--GRKTLGLRPAPEERDPDHTR-----
----------------GSDSLALDQIHLGGPDLP-------------ADARTPLEGDAGP
SKPATEVPDTP-------EPFTATQGPP-KPDSSGEEVAKGIL-APEQEACHDVCAHGDD
GAESSSPPKEALGAEHQGHEAL---------------KPVVH------------------
----------GPGVCPTASLEVGQLGPPSPVEEGR-----ATLGHRLPMAVGSEVGLSSC
SESPSR----AVPRLGGHCA-KDPAPTSPLPLRQP-------------------------
------------------------------------------------------------
-----------------------------------------------KPVLGPGRGEQAQ
AALGALGPTPLQPPESPIGGLPSAPQDRIQG----PE--PPAPGVLMEAVPSPLASPAPC
PCRGPREDLVEGAEPLGSPSHPPPRPRTQRAV--A-ASSGITNPPGAGQ-VSLPPHPTLL
SPKAAPKRGTHAKDPASRLSPPRQVPPGSGPRSPAG------------------------
-----------------PRGLPATEQQDDGDSLEED------------------------
---------------------------------------------------------SP-
RALGSGQHSD-----------------SGPQ--TAQCPAQA---PAGSGSEETVAKAKQS
RSEKKARKAMSKLGLRQ--IQGVT----RITIQKSKNILFVIAKPDVFKSPASDTYVVFG
EAKIEDLSQQVHRAAAEKFKVPSEPSALVPESAPGPRVRPECEEEE--EE-EEEEEVDEA
GLELRDIELVMAQANVSRAKAVRALRDNQSDIVNAIMELTM-------------------
----------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
QPCALT-PGPSALALTFLPSKPGARPPPEGASWDAGSHQAPSTWAVPAKSSPS-------
-GPEVLPIGGPVPGALEPRIAMGEETRRA-PPLP---------------WAALPELRDRV
R-GPASPSPPPAAHPQGALLTPVPATDPDCYFTPPSSPSQTTATLLPGRG-----W--AA
ETELQTEPGDSPPASPSGSYVTADGDSWGS------SPSCSLSLLAVAEGLDVPSGWSFS
PPGSEA--------------NEREPTPAESLGSPSPESSLSGDSSSSWDQE---GHFFEL
DFLANDPMIPAALLPFRGSLIFQVEAVEVTPLPPEEEPD---------------------
---GEDGDGSTFASSLQSLSDLSITEGVDEAFAFRDDASAASSDP--DSASYTGVED-ER
LYSEEPHAQPPL----------------------------------PAPWGTAP------
-GVS----------DWAEL-----EITRAGPTSGQVSAASPALPPSQEAP--GLAGVPPR
ALGGEAGSAVGAVPVSMGAPQPWQEGAGTALGPRVD------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------QG--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------GAGCPDT------------------------------------
------------------------------------------------------------
----------------PQSVKA-------------------------GAP----------
------------------------------------------------------------
----------------------------GV------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------------LTEED
HTSAQ-------------GP----------------------------------------
------------------------------------------------------------
------------------------------------------VPAATHLPLQTDAGCAL-
--------GAEPVTAAVQ-------------QE--GGETLGLKPAPEKD-TGHAG-----
----------------DPEPAALDQTQQGGPDPA-------------ADARTPWASPIAI
DA----------------LLGLEALDPPEPTSGGKEEP-----AGPDRGASLCAHLPTGE
GAEPCSLPEEARRAENQGSGGLEPAPGVTG------------------------------
----T--------APGSGCPKLGLVQPPSPAEDGR-----VTPRPELPAAVAS-------
-ESPSR----AVPRLGRGCP-EEPALESPPASQQL-------------------------
------------------------------------------------------------
-----------------------------------------------EPVHGPGGEEPAG
AAPGVFGPPAP------------RPQDRLPG----PE--PSTPALLSGAAPPPTEPRVPC
PCQCPQEDFVEEVETL---GPPPPQAGTQQAM---ATFSGTTNPPRAGQQVSLQPHPPLF
SPEVAPVGDTYTKDPALQTPSPRQVPPGSGPWSLSS------------------------
-----------------PRDLQAAELQDDGDSLEEE------------------------
----------------------------------------------------------SP
RGP-----SD--S-LEESSAELEEQALSGPQ--ATQCPAQA----LAGRSEETMAKAKQS
RSEKKARKAMSKLGLRQ--IHGVT----RIAIQKAKDILFVITKPDVFKSPASDTYVVFG
EAKIEDLSQQAHRAAAEKFKVPAEPSTLGPESTPGPRVRLGCEENR--E---EDEEVDEA
GLELRDIELVMAQANVSRAKAVRALRDNQSDIVNAIMELTM-------------------
----------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
--------------MPGEAARAELLLPEAGGPGPRTDLSCDAAEAT-TPKGDR------L
EHCAPT-SGPSALALTFLHGKPGARPPPEGASWDAGPGRAPSAWAVQAEGGPSPG-----
-PAEVRPAEGPLPASLEPRIVMGEETCQA-APLP---------------RATMPELRDWE
G-GHANLNPPPELCSQGDPPVPFPAPDSDSYFTPPSTPTKTASTLLPGPGPHRDSQ--DA
QAE----LGDSPPASPTGSYITADGDSWAS------SPSCSLSLQALAEGLDVPSGWGFS
PPSSVV--------------DERELPPAGTPDSSSPESSLSADSSSSWGQE---GHFFEL
DFLANDPMIPAYLLPFQGSLIFQVEAVEVTPLPHEEEEVEEE-EQE---EEQEVPLPRGD
-LAGEGEDDSTFASSLQSLSDLSITEGVDEAFAFRDDTSAASSDP--DSASYTGADD-ER
LYSGEPHAQPTTLLQE----SPGE----------------------AASWGPE-----LT
LGVSKGEAGQAAKSQEPIS-----EITRVGPAAAQVSSA-MALHIPQESL--DHTGMSPQ
AQGEEPGSTMGPVPVAPVTSQPLQEGDTATLGPEPWISKGEADLNCLQTLKEDTGQGFAT
ATSPEPQPEVDPAALPPLQ-----DAGIP--WVQESASETSLEPQLEEEGLTASSPLQDA
GIPWVQGSAS-----EASPEPQSEEEDLTASSTSQDAGLPLVQGSASEACPEPQSEEEDL
TASSPLQDAGPHLVQGSASEASPEPQSEEDLKASSTSQDAGLPLVQGS-ASEVSPEPQSE
E----------DLTASLPLKDEGLPLVQGSASEASLEPQSEEEDLT-ASLSLKNEGLPLV
QGSASEASLEP------------QSEEEDLTASLSLKNEGLPLVQGSASE----------
-ASLEPQS---EEDLIASLPLKDECLPLVQGSASKASPEPQSEEDLTASLSLKNEGLPLV
QGSASKASPEPQS--EEDL-TASSPLQDECLPLIQGSASKASSEPQSEEKDLAASSPLKD
ECLPLVQGSASEASPEPQSEDLTASSPLQDAGLPLTQGSAS------EASPE--------
---PQSEDLT------ASSPLQDAA-L----------RLVQGSVFETSP--EPHS-EE--
------------DLTASPPLQDAGLPLVHGSASEASPELQ--SEEVTASPPLQDAGLPWV
QGSASEASPDHQSDLKASLPLQDAGLPLVHGSASEASPEPQSEED-LIASSPLKDECLPL
VQGSASEASPELQSKEEVTVSPPLQVAGLPLVQGSA------SDATSEPQSEE---LTAS
SPLQDAGLHLVQGSA--SEASPEPQSEEEELTASSHLQDAGLPLVQGSASEA--------
-----SPELQSKEEVTVSPPLHVAGL-----------------PLVQGSASNATSEPQSE
ELTASSHLQDAGLPLVQGSVSEASPEPQSEEE----ELTASSHLQDAGLP--LVQGSVSK
ASPEPQSEEEELTASPSLQDAGLPLVQGSASEVSPEPQSEEEDLTASPPLQDAGLPLVQG
SASDASSEPQSEEEELTASPTLQDAGLPLVLGSVSEASSEPHSEEEELTASLPLQDTSLP
LVQGSASDASSEPQSE-----EDLTASPTLQ---DAGLPLVQG--SVSEASPEPHSEEEL
TASPPLQDTGLPLVQGSVSEASLEPHSEEEELTASPPLQ---DAGLPLVQGSVSEASL--
--EPHSEEEEL---TASPPLQDAGLPLVQGSASDAS--SEPQSEEEELTASPTLQDAGLP
LVQGSASDASSEPHSEEELTASPPLQDAGLPLVQGSVSEASSEPHSEEELTASPPLQDAG
LPLVQ-------------GSASDASSEPQ----S--EEDLTACPTLQDTGLPLVQGSASK
VSPEP----------------QSDLTA------------SPTLQDAGLPLVQGSA-----
----SKASPEPQSEEDLTAFPPLQEAGLPSSQVSAT-------SASP-QAPMTDTGCIQ-
--------ETEPTATAAH-------------RK--GRKTLGLRPAPEERDPDHTR-----
----------------GSDSLALDQIHLGGPDLP-------------ADARTPLEGDAGP
SKPATEVPDTP-------EPFTATQGPP-KPDSSGEEVAKGIL-APEQEACHDVCAHGGD
GAESSSPPKEALGAEHQGHEAL---------------KPVVH------------------
----------GPGVCPTASLEVGQLGPPSPVEEGR-----ATLGHRLPMAVGSEVGLSSC
SESPSR----AVPRLGGHCA-KDPAPTSPLPLRQP-------------------------
------------------------------------------------------------
-----------------------------------------------KPVLGPGRGEQAQ
AALGALGPSPLQPPESPIGGLPSAPQDRIQG----PE--PPAPGVLMEAVPSPLASPAPC
PCRGPREDLVEGAEPLGSPSHPPPRPRTQRAV--A-ASSGITNPPGAGQ-VSLPPHPTLL
SPKAAPKRGTHAKDPASRLSPPRQVPPGSGPRSPAG------------------------
-----------------PRGLPATEQQDDGDSLEED------------------------
---------------------------------------------------------SP-
RALGSGQHSD--S-HGESSAELEEQDLPGPQ--TAQCPAQA---PAGSGSEETVAKAKQS
RSEKKARKAMSKLGLRQ--IQGVT----RITIQKSKNILFVIAKPDVFKSPASDTYVVFG
EAKIEDLSQQVHRAAAEKFKVPSEPSALVPESAPGPRVRPECEEEE--EE-EEEEEVDEA
GLELRDIELVMAQANVSRAKAVRALRDNQSDIVNAIMELTM-------------------
----------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------MPFSVSADLACDAPAAT-ILGEDR------R
EPHALT-PGPSPLALTFLPSKPGARPQPEGASWDAGHGGGPSSWADPAEGGPNPVLLPEG
LHPQA------LAATLEPRIVMGEETCQA-PPSP---------------RAALPVLREQ-
-----------ELCSQDDPPVPSWSPVPEPYFTPPSTPTEATYALLLGHGLHRDAW--DP
EAE----LLDSLASSPSGSYVTADGDSGTL------SPSCSLSLLAPTEGPDFPLGWSFS
PPESAA--------------EEWEQHPAET---PSSESSLSGDSGSSWGQE---GHFFDL
DFLANDPMIPAALLPFQGSLIFQVESVEVTPLSPEEEEEEE--------VAPDNLAPDGE
-AARQDEEDSASASFLQSLSDLSITEGMDEAFAFRDDTSAASSDS--DSASYAGADD-DR
LYSGEPHAQPSALLQDAGQKAEQECSGR------------------AVSWSAEPRGTAPT
PQVPEGE-TRLSQSQESVA-----GISEEGLASGRESAAAVTPHTGQVTA--EATPQVG-
------------------------------------------------------------
------------------AEVDSVARGTPATQAPAHPS-------------------QDR
SA--ALGRPPGAV--EAEP------------------------------------ALQEA
AGSSPL-------------------------ELTEPQGGPGLPEGLEF-VAAATLGPLRA
EGGVPKPQDSPDTELLP-LLDEDPTSGLE-------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------SV
AAATLESQEAEGGVPSPQDSPDTELLPLPDEDPTLGQECMA------AATLGPLQAEGGV
LL-PQDSPES------LPLSLQEED-L----------ISSLEAAAVATS--GSQE-AAS-
------------GVP---------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------LPQNSAEAPLP--LLEDENST
SSPEVMAA----------------------------------------------------
------------------------------------------------------------
---------------------------------------AIQ------------------
--------------------------------------------------GSLQA-----
-------------------------------------------------------KQGT-
------------------------------------------SLPQD-PPESSPP-----
------------------------------------------------------------
------------------------------------------------------------
----------------------LQAGDSA-------SGLEAVVVATP-GALKAQASCTP-
--------GSKAVA----------------QQE--LGVASGPRPVPKEWVAAPPG-----
----------------DPEPVALNQAPQDGPKPGAEAGTLGPQGEE--------------
---------------AGPTLDMEVASPPEAALGPRE-GDPGR-SPVEQETCPEAQAPTED
RAKTRLPPGEAHGPKNQRARGPKPPAQGHG-P-----RSAPRG-----------------
--ARD-----APKALRATCPEVSQAQPLSPGREGRALGSKGTPASRLPAALASGAQQGSC
PGSPAR----AVSRLGGEGP-IKPGPSASPSPQL--------------------------
------------------------------------------------------------
-----------------------------------------------EP--AAGHGQRPL
AAPSLLSPSPPPLPRTAARGPPSAPRTRLLD----PN--PSAPVA-------------SR
PCRGPQEDSVEGEEPPASRGPLPPRVGAQRAT----AASGTTQPRGARQRFGLAPQPPLL
SPKAAPE---GAKEPASRTSPPCQVPPLLGSRGPRG------------------------
-----------------PQGLPALEQQEDEDSLEED------------------------
----------------------------------------------------------SP
RAPGSGQHSD--S-HGESSAELDEQDASAPH--A-QRPAQA----PTGSSEETIAKAKQS
RSEKKARKAMSKLGLRQ--IQGVT----RITIQKSKNILFVIAKPDVFKSPASDTYVVFG
EAKIEDLSQQVHKAAAEKFKVPSESLALVPESAPGPQLRPELEEEE--E---EEEEVDET
GLELRDIELVMAQANVSRAKAVRALRDNHSDIVNAIMELTM-------------------
----------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
--------------MPGEAAGVELPLPEAGGPGSRTDRSCDAAIAT-ILKEDQ------L
EPHGLT-LGPSPLALTFLSSKPGARPQPEGASWDAGPSGAASAWVDPAEGSPSLVALPEG
LPLRPVPAEGPLPTTLEPRIVMGEETCQV-IASP---------------RAAWPVLRDRE
G-GH----PPPELCSQGDPPVPSPSPDLESYFTPPSTPTKTTYALLPDHGPHRDAW--DL
EAELLDELLDSTPASPSGSYITADGDSWAS------SPSCSLSLLAPAEGLDFPSDWGLS
PSGSVV--------------DDLEPHPEAPPESPSSESSLSADSSSSWSQE---GHFFDP
NFLANDPMIPAALLPFRGSLIFQVEAVEVTPLPQEEEEDEEEIAATAAA--AAAATPDGD
-LAGEVEDDSTSASFLQSLSDLSIIEGMDEAFAFRDDTSAASSDS--DSASYAGADD-DR
LYSGEPHAQPSAQNTEQAYRSRAT------------------------FPGI-----EFT
PQTSEQ-EICLTNSQESVA-----EIAEEILTLGIESEATRTPPDQQ-------------
------------------------------------------------------------
--------------AAPDHQAEEAPTVTPWVGNKVDSVA--------EQASKALPEPCHE
GISTILGCKPLTA----------------------EAIPDLQQGASPTSCPVLPENLKEE
G--------------------------------------QGVPSTLEY-VAVALEGPWKA
EGGVTILQDPLMTLPPLLQ-STVPTSGPE-------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------SV
AVVALEPQQNEGCLRVLPDVPVVLPPPLQSAAPTSGPEAMA------VATFEFQQAKEGI
PE-LQDSPMA------SPPAPQGSD-P----------TSEPEPEVVVTM--RSQQ-DEG-
------------IVT---------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------------VPQES
PTASSPTLQSSDPTSGQEHEVAATWGPQQAEE----SITRPQVAPVASPS--PLQGLEST
SD----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------LESVVVGTLESQQDEGI-----------------------------
------------------------------------------------------------
-----------------------------------------ATATQDTPVMAPPPLRGTD
------------------------------------------------------------
------------------------------------------------------------
---------------------------S-------TSDPELVASDTS-QALQREAGYTP-
--------GTKPSVSEAH-------------QE--LGVASGPRSVPKEGDAEPPP-----
----------------HSAPPASNQAQQNGSEPGDKSDSFGTPEEES-------------
----------------DPTLST---KTSEPTSCMGAKAAENMS-APKQGACL----EAHD
GVKTHSPQREALRAKNKRGRGTKPPGQGNGPK-----SAASQV-----------------
--AME-----TFRAHSAARSEVSQPQLMS---------NKDTSGPRLPVAVSVQARLGSC
PGSPAR----ATCALSRVFS-EETAR----------------------------------
------------------------------------------------------------
---------------------------------------CAPPFQHLEPMLGLGSAEPPK
VTPGTLDLSP----DNSAGDLLTTPQNRFLD----PDPAP---STLDRAFQSSPGPPDPC
LCPPPQKASLE-EKPPASRGPM-PRAGAQGAA--AITTSGCTKPLGARQRVSLSPHST-L
NPKVTPT---DAKDLACIISSPCQVPPPSGTQNPLG------------------------
-----------------PRGFPAHEQ-EDEDSLEEDSQRAPGSGQ---------------
------------------------------------------------------------
-------HSD--S-HGESSGELDEQDLS-PQ--KSQCPAQG----PASSNEETIAKAKQS
RSEKKARKAMSKLGLRQ--IQGVT----RITIQKSKNILFVIAKPDVFKSPASDTYVVFG
EAKIEDLSQQVHKAAAEKFKVPSESSALVPELSPGPRVRPECEEQE--E---EDEEVEDA
GLEPRDIELVMAQANVSRAKAVRALKDNHSDIVNAIMELTM-------------------
----------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
EHCTPP-PRTSPLTVMFLPSKSGTRPQPEGASWDAGPDRALSAWAL-SAEGSTSP-----
-VPPEGQLTEALSATLEPRIVMGEENCRP-PTRP---------------RAASQELRDWE
G-GHANLNLPPELCSQGDSPVPFPHPDPDSYFTPPSTPLQTTCALAVGLGLCT--EACDS
EAE----LLDSPPTSPSGSYITADGDSWAS------SPSCSLNVLAPVQGPDLPSGWDFS
PSGPMAEGREP--------------PAVRPPSSYSSASSLSADSSSSWGQE---GNLLDL
DFMANDPMIPAALLPFQGSLIFQVDAVEVMLLPGPEEEEKS---------ETKAPGPGRD
-LGEEGEDDSPSASFLQSLSDISIIEGMDEAFAFRYDTSAASSDSDSASASYAGADD-ER
FYSGELPVQPSALLQDCRCKVEE-------RRDGPLFWAE-----EPTPWTERR------
-------SLKTLT-------------------------------------------QDVA
----EGFLS---------------------------------------------------
----------------VQD---AAASVTALS-----------------------------
----------------------------------------W-----------P-------
--------AEAGLVESAAVGPPQP--------G----------------------E----
-------------------KTADSSVGQEDVAMATPLPLQGKVN---------A------
---A--------------------------------------------------------
-------------------------LGDEAG-AE------------ETPQTVKEK-----
------VSIMPCPD----------------------------------------------
------------------------S------------------------------FQ---
---------------------KEKEEVGP---------GL--------------------
-------TSGQESFATATP-------------------VHLYKDVLR-QEPVSMTTS---
-----------------------------L-----TLQEKS-------------------
-LTLHQE-------------SVSM-----ATPL--PL-----QRDAAFPLGQEPVAMATL
QALQAA---------------------------------------------------AGC
PLGRAPAA-------------PKAAL----------------------------------
---------------------------AQQEVCVALGLMAASELMAVAL-----------
ST-EP----------------------------------------------------EAE
PVALDQ----------------VQQD-------A------PHLVAEAMTS----------
VASGKDTDLISEPVPRRQEAAEGPS---GSE----------------PGTGIGFQH----
------------TDDGAE---GLESQRDEGLLVAPGAGKA---------PGS--------
-----------------------------------------SSLVVDLALVPRW-AR---
--EQP--GL----------------LA---------------------------------
---------------------------------------------------------AVV
SEAEL------------DSSSESLAGSVPEP-GKG----------------------C--
--------------------PG--E-----------------------------------
-------PMPATTA---P--PTSWG-REPGQGGVEEQAQVA--SSSLSLPLQFPG-----
-----P----------Y---A-QDL-----------------------------------
------------------------------------------------------------
---PTK-AQDRSSHPDPFL--P----A------FSTGVARPHLA-APVPC----------
--------LCQWPR--EDCRDKEPP----------------------G------------
-LQTLAQVPRAAAAISGNLVPPGAG-----------------------------------
------------------------------------------------------------
------------------------------------------------------------
------QQAGLSCPL---PHL---SSKV------TPMGGPCAKALSA-------------
------------------------------------------------------------
-----------------HICDPCQVPLGSGPCPPA-------------------------
----------------SPLGLPVPEQQEDQDSLEE-------------------------
---------------------------------------------------------DSP
RAPGSGQHSD--SQAESSAPEMEEQDLAALR--TARCPPQA---PAVGSSEETIAKAKQS
RSEKKARKAMSKLGLRQ--IQGVT----RITIQKSKNILFVISKPDVFKSPASDTYVVFG
EAKIEDLSQQVHKAAAEKFKVPAEPSARTSESAPGVQVTPECQEE------EEEEAVDET
GLELRDIELVMAQANVSRAKAVRALRDNHSDIVNAIMELTM-------------------
----------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-MGSLLCT-GLD-----PLGLDTPTPASHRLRLGH-------------------------
--------------------------------------------------------LLPV
SLAGGPA----------LVSPLHRAVGELLCGARVLQAQLT---HSLGAGEETISKAKQS
RSEKKARKAMSKLGLRQ--IHGVT----RITIRKSKNILFVITKPDVFKSPASDIYIVFG
EAKIEDLSQQVHKAAAEKFKVPMEHSPLITEAAPALAIKEE---S------EEEEEVDET
GLEVRDIELVMAQANVSRPKAVRALRHNNNDIVNAIMELTM-------------------
----------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------EESISKAKQS
RSEKKARKAMSKLGLRQTXIHGVT----RITIRKSKNILFVITKPDVFKSPASDIYIVFG
EAKIEDLSQQVHKAAAEKFKVPMEHSPLITETAPALTXE-------------EEEEVDET
GLEVRDIELVMAQANVSRPKAVRALRHNNNDIVNAIMELTM-------------------
----------------------------------------------

------------------------------------------------------------
------MSALPLALRSARRAGARSLGLIGGRGSADVIYAPPPPSRGAVAVLATPSALTDR
GTERQGYRQAHVQAMPGEAAGAELPLPEAGGPGSRTDHSCDAAIAT-ILKGDQ------L
EPHGLT-PGPSPLALTFLSSKPGARPQPEGASWDAGPSGAASAWVDPAEGSPSLVVLPEG
LPLRPVPAEGPLPTTLEPRIVMGEETCQV-IASP---------------RAAWPVLRDRE
G-GHPALHPPPELCSQGDPPVPSPPPDLESYFTPPSTPTKSTHALLPDHGPHRDAW--DL
EAELLDELLDSTPASPSGSYITADGDSWAS------SPSCSLSLLDPAEGLDFPSDWGLS
PSGSVA--------------DDLEPHPAAPPEPPSSESSLSADSSSSWSQE---GHFFDP
NFLANDPMIPAALLPFRGSLIFQVEAVEVTPLPQEEEEDEEDVAATAAAAAPAAATPDGD
-LAGEGEDDSTSASFLQSLSDLSIIEGMDEAFAFRDDTSAASSDS--DSASYAGADD-DR
LYSGEPHAQPSAQNTEQAYRSRAT------------------------FPGI-----EST
PQTSEQ-EICLTNSQESVA-----EIAEEILTLGLESEAMRTPPDQQ-------------
------------------------------------------------------------
--------------AAPGPQVEETPTVTPWVGNKVDLVV--------EQVSKALPEPCQE
GISTTLGCKPLTA----------------------EAIPDLQEGASPSLCPVLPEK-KEE
G--------------------------------------QGLPSTLEY-VAVALEGPWKA
EGGVTIPQDPLMTLPPLLQ-STVPTSGPE-------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------SV
AVVALEPQQNEGCVTVLPDVPVVLPPSPQSVDPSSGPEAMA------VATYEFQRAKEGT
PG-LQDSPVA------ASPALQGPD-P----------TSEPEPEVVVTS--RSQQ-DEG-
------------IVT---------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------------VPQES
PTASSLTLQSSHPTSDQEREVAATLGPQQAEE----GVTIPQVAPVASPS--LLQGLEST
SD----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------LESVVVGTPESQQDEGI-----------------------------
------------------------------------------------------------
-----------------------------------------ATATQDTPVMAPPPLRGTD
------------------------------------------------------------
------------------------------------------------------------
---------------------------S-------TSDPELIAPDTS-QALQREAGHTP-
--------GTKPSVSEAH-------------QE--LGVASGPRPVPKEGDAEPPP-----
----------------HSAPPASNQAQQNGSEPGYKSDSFGAPEE-S-------------
----------------DSTLST---KTSEPTSCMGEKVAANMS-APKQGACL----EAHD
GVKTHSPQREALRSKNKRGRGTKSPGQGNGPK-----SATSQG-----------------
--AVE-----TCRAHSAARSEVSQPQLRS---------NEDTSGPRLPVAVSVQARLGSC
PGSPAR----ATCTLSRVYA-EETSR----------------------------------
------------------------------------------------------------
---------------------------------------CAPPFQHLEPMLGLGSAEQPK
VTPGILNLSP----DNSAGDLLTTSQNRFLD----PDPAP---STLDRASQSSPGPPDPC
LCPPPQKASEEEEKPPASRGPM-PRAGAQGAA--AITTSGSTKPPGARQRVSLSPHST-L
NPKVAPT---DTKDLACIISSPCQVPPPSGTQNPSG------------------------
-----------------PREFPALEQ-KDEDSLEEDAQRAPGSGQRWESH----------
------------------------------------------GESSSELDEYLAPPPDAQ
RTPGSGQRSE--S-HGESSSELGEQDLS-PQ--KSQCPAQG----PAGSNEETIAKAKQS
RSEKKARKAMSKLGLRQ--IQGVT----RITIQKSKNILFVIAKPDVFKSPASDTYVVFG
EAKIEDLSQQVHKAAAEKFKVPSEPSALVPELSPGPRVRPECEEQE--E---EDEEVEEA
GLEPRDIELVMAQANVTRAKAVRALKDNHSDIVNAIMELTM-------------------
----------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---GSSNDSE--S-NEGSIPELEEPEV-SEPRMAQTQAQLT---HSLGTGEESISKAKQS
RSEKKARKAMSKLGLRQ--IHGVT----RITIRKSKNILFVITKPDVFKSPASDIYIVFG
EAKV--------------------------------------------------------
------------------------------------------------------------
----------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
--------------MPGEAARAELLLPEADGPGPRTDLSCDAAAATTILGGDR------R
EPCALT-PGPSHLALTFLPSKPGARPQPEGASWDAGPGGAPSAWANPGEGGLSPMLLPEG
LSSQALSTEAPLPATLEPRIVMGEETCQA-LLSP---------------RAARTALRDRE
G-GHASSDPPPELCSQGDLSVPSPPPDPDSFFTPPSTPTKTTYALLPGCGPLGDAG--DS
EAELWDELLDSPPPSPSGSYITADGDSWAS------SPSCSLSLLAPAEGLDFPSGWGLS
PQGSMA--------------DERELHPAGTPEPPSSESSLSADSSSSWGQE---SHFFDL
DFLANDPMIPAALLPFQGSLIFQVEAVEVTPLSPEEE-EE----------AVADPDPGGD
-LAGEGEEDSTSASFLQSLSDLSITEGMDEAFAFRDDTSAASSDS--DSVSYTEADD-ER
LYSGEPHAQAT-LLQDSVQKTEEESGGGAKGLQVQEG---------TMSWALE-----AA
PQTSDRGAP-LSQRQESIS-----EVTEEGLALGQESTATVTPHTLQ-------------
------------------------------------------------------------
--------------VAPGLQVEVATRVTPQAGEEKADSTTGQASAAMAM-----PQPSQE
GISEILGQESVTA--EKLPTPQE--------------------ETSLTLCPDSSQNLKEE
GG-------------------------------------LDLPSGPKP-VAAASLMPQQA
EEDLTLPQDPA-VTPPLPLQDTDLSSAPKPVAAATTVL----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------RQAEEDLTLPQGPAVTPPLPLQDTDLSSAPKPVG------AASLVPQQAEDDP
TL-PQDPAVT------PPLPLQDTD-L----------SSAPKPVAAATI--VPRQ-AEE-
------------DLTLPQDPAVTP------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--PLPLQDTDLSSAPKPVA-----------------------------------AATT--
--V---------------------------------------------------------
------------PRQAEEDLT----------LP------------QDPAVTPPLPLQDTD
LSSAP-------------KPVGAASLVPQ-------------------------------
-----------------------------------------------------Q------
----AEEDPTLPQDSAMTPPLPLQDTGPTSGP-------EPLAVATP-QTLQAEAGCTP-
--------GTEPVATMAQ-------------QE--VGAALVQ------------------
--------------------------------------------------G---------
---------------------------------------------RGWASGR--------
------------------------------------------------------------
----------AP------------------------------------------------
-------------HPTHGCS----------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------ALTFSQA----PAGSSEETIAKAKQS
RSEKKARKAMSKLGLRQ--IQGVT----RITIQKSKNILFVIAKPDVFKSPASDTYVVFG
EAKIEDLSQQVHKAAAEKFKVPSEPSALVPESAPRPRVRLECKEEE--E--EEEEEVDEA
GLELRDIELVMAQANVSRAKAVRALRDNHSDIVNAIMELTM-------------------
----------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
--------------MPGEAARAELLLPEADGPGPRTDLSCDAAAATTILGGDR------R
EPCALT-PGPSHLTLTFLPSKPGARPQPEGASWDAGPGGAPSAWANPGEGGPSPMLLPEG
LSSQALSTEAPLPATLEPRIVMGEETCQA-LLSP---------------RAAQTALRDRE
G-GHASPDPPPELCSQGDLSVPSPPPDPDSFFTPPSTPTKTTYALLPSCGPLGDAG--DS
EAELWDELLDSPPPSPSGSYLTADGDSWAS------SPSCSLSLLAPAEGLDFPSGWGLS
PQGSMA--------------DERELHPAGTPEPPSSESSLSADSSSSWGQE---SHFFDL
DFLANDPMIPAALLPFQGSLIFQVEAVEVTPLSPEEE-EE----------AVADPDPGGD
-LAGEGEEDSTSASFLQSLSDLSITEGMDEAFAFRDDTSAASSDS--DSASYAEADD-ER
LYSGEPHAQAT-LLQDSVQKTEEESGGGAKGLQVQEG---------TMSWALE-----AA
PQTSDRGAH-LSQRQESIS-----EVTEEGLALGQESTATVTPHTLQ-------------
------------------------------------------------------------
--------------VAPGLQVEAATRVNPQAGEEKADSTTGQASAAMAM-----PQPSQE
GISEILGQESVTA--EKLPTPQE--------------------ETSLTLCPDSPQNLKEE
GG-------------------------------------LDLPSGPKPPVAAATTVPRQA
EEDLTLPQDSA-MTPPLPLQDTDLSSAPKPVDAASLVP----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------QQAEEDPTLPQDPAVTPPLPLQDTDLSSAPKPVA------AATIVPRQAEEGL
TL-PQDPTII------PPLPLQDTD-L----------SSAPKPVAAATT--VPRQ-AEE-
------------DLTLPQGPAVTPPLP---------------------------------
-----------------------------------------------------------L
QDTDL-S-------------SAPKPV-------------------------AA---ASLV
PQQAEEDL----------------------------------TLP---------------
---------------------------------------------------------QDP
AVTPPLPLQDTDLSSAPKPVAPATTVPRQAEE----DLTLPQDPAV--------------
--------------------------------------------TPPLPLQDTDLSSAPK
PVAAATTVPRQAEEDPT-------------------------------------------
---------------------------------------LPQ--------------GPAV
TPPLPLQDTDLLSAPKPVD-----------------------------------AAST--
--V---------------------------------------------------------
------------PQQAEEDPT----------LP------------QDPAVTPPLPLQDTD
LSSAP-------------KPVDAASLVPQ-------------------------------
-----------------------------------------------------Q------
----AEEDPTLPQDSAMTPPLPLQDTGPTSGP-------EPLAVATP-QTLQAEAGCTP-
--------GTEPVATMAQ-------------QE--VGAALGPRPAPEEKNVALSR-----
----------------VPEPAALDQVQQDDPQPA-------------AEAGTPWAAQEDA
DS----------------TLGMEALCLPEPASGAGEEVAETLS-RPGWEACLEALVHTSD
GAKPDSPQKETLEVENQQGGGLKPPAQEHG-P-----GSTLGG-----------------
--AGE-----VPEAPPAACPEVSQAWLLSPAREGRGLSGKSTLEPTLPSAVATEASLDSC
PESSVG----AVSRLDRGCP-DAPAPTSAPTSQQQEP-----------------------
------------------------------------------------------------
----------------------------------------------LEPVLGLGSVERPH
KAPSVLGPLLLQPPENLGKGLPSAPPDRPLG----PD--LSAPGTLAGAALPPLEPPAPC
LCQDLQKDSVEEEEPPGSLGLPTPQAGAQPAA---AAVSGTTQPLGTGPRVSLLPHSPLL
SPKVASM---DAKDLALQISPPCQVPPPSGPQSPAG------------------------
-----------------PQGLSAPEQQEDEDSLEE-------------------------
---------------------------------------------------------DSP
RALGSGQHSD--S-HGESSAELDEQDILAPQ--TAQCPAQA----PAGSSEETIAKAKQS
RSEKKARKAMSKLGLRQ--IQGVT----RITIQKSKNILFVIAKPDVFKSPASDTYVVFG
EAKIEDLSQQVHKAAAEKFKVPSEPSALVPESAPRPRVRLECKEEE--E--EEEEEVDEA
GLELRDIELVMAQANVSRAKAVRALRDNHSDIVNAIMELTM-------------------
----------------------------------------------

-----------------------------SSSLPPTRTARR-------------------
---------TLARDAGRR---AGRRAVAAQ---------------ATLARG--TDGLADA
GRKD-GHGPAHVKAMPGEASRAELPLSEAGGPGSRTGLSCDAAAVS-VLKGDQ------R
EPHALT-PGPSPLAPTLLPSKPGARPQPEGASWDVGPGGVPSAWVDPAEVPNPALL-PEG
LSLQPLPAKAPLPDTLEPRIVMGEETCQA-HTSP---------------RGAWPVLRDWE
G-GHPVLHPPPELCSQGDCPVPSPPSDPDSYFTPPSTPT---CALFPAHGPHRDAW--DP
EAE----LLDSAPASPSGSYITADGDSWAS------SPSCSLSLMAPGEGLDFPSGWGLS
PSESVG--------------DEQESQPEAPSEPLSSESSLSADSSSSWSQE---GHFFDL
NILTNDAMIPAALLPFRGSLIFQVEAVEVTPLPQEEEEEEE---EE---AEADAPVPGGD
-LAGDDEDDSTSASFLQSLSDLSIIEGMDEAFAFRDDTSAASSDS--DSASYAGADD-DR
LYSGEPHALLHDRAQKTEE-HRAG----------------------DAFWGTV-----PM
LQTSQQETH-LPQSQEPTA-----EITD-----G--------------------------
-------LTEAPAP----------------------------------------------
---------LPNLQTVPGLQVEDTTTVIPWVGGKQVDSTAEQ------------------
------------------------------------------------------------
----------------------------------------------AP-ASGSSPHPSWG
MSS---------ALGAEPVTAESSPALQE-----------ET------------------
---------------------------SSTLCA---------------------------
-----------------VLPEN--------------------------------------
---------------------------------------------LKEE-----------
-----------------GQGPLSALKPVA--GATLGAQQAE------GSVTV--------
---PQDSPMA------TPPPMQGTD-L----------TSGSKLVSVVTL-----------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------APQQ----------VEGSDIV
----PQD-----------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------SPM
ATPPPLQGIDPT-----------------------------------------SGPES--
--VA--------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------QPE--SGTATGHRPVPEEQEEAHAGD----
-----------------SEPPASSQVQQDGPEPVV-------------QSRKLWAPGK--
EA----------------GPTLGTRAPE-PASGTRGKVAQGLV-APEHKAHPEAQ-----
--------KENLRAKNHRGGGPKPPGQGRG-P-----KSAAQG-----------------
--AG-----QAPKARAIACPQVSQVQLL--SLNSK-----DTPGPRLPMAVTTEVRLSSC
LGSPAR----ATHRQDRACP-EEPVRSTP-PSRQQ-------------------------
------------------------------------------------------------
-----------------------------------------------EPTLGLSSEEQPR
VTPCLLSPS-PQLPRTPARGLSNTARNRLLD----SN--PSVPCVLTRAASPSPGRPVPC
LCPEPRKASVEGEESPASRGLLLPGVGAQQAA--ATTASGSTPSLGAQQQVSLSLHSALL
SPKVVPT---DAKDLACGISSPCQVPPPSGTLNPSG------------------------
-----------------PQGLLALEQQEDEDSLEEGKEVREAG--PWVGGASA-------
-------------------------------------------V---VSLSHFSPSPDSP
RAPGSGQHSD--S-HGDSSTELDERDVSAPQ--TAQCPALTFPQAPAGSIEETTAKAKQS
RSEKKARKAMSKLGLRQ--IQGVT----RITIQKSKNILFVIAKPDVFKSPASDTYVVFG
EAKIEDLSQQVHKAAAEKFKVPSESSALAPELAPGPHVKPECEEQE------DEEEVEEA
GLELRDIELVMAQANVSRAKAVRALRDNHSDIVNAIMVSDCWP--LPHFPERSC--CWLC
QGETLSRHDPLHVFL--------QELTM------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------E-GLW-----GVEVNVAFTA---------------------------------
---------------------------------------------------------TPM
SCVGSCNESE--S-NDESIPELEEPEG-AEPRPMQTQAPLT---HSLGTGEESISKAKQS
RSEKKARKAMSKLGLRQ--IHGVT----RITIRKSKNILFVITKPDVFKSPASDIYIVFG
EAKIEDLSQQVHKAAAEKFKVPMEHSPLITETAPALTIKEE---S------EEEEEVDET
GLEVRDIELVMAQANVSRPKAVRALRHNNNDIVNAIMELTM-------------------
----------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
--------------MPGEAARAELLLPEADRPGPRTDLSCDAAAATTILGGDR------R
EPCALT-PGPSHLALTFLPSKPGARPQPEGASWDAGPGGAPSAWADPGEGGPSPMLLPEG
LSSQALSTEAPLPATLEPRIVMGEETCQA-LLSP---------------RAARTALRDQE
G-GHASPDPPPELCSQGDLSVPSPPPDPDSFFTPPSTPTKTTYALLPACGPHGDAR--DS
EAELRDELLDSPPASPSGSYITADGDSWAS------SPSCSLSLLAPAEGLDFPSGWGLS
PQGSMV--------------DERELHPAGTPEPPSSESSLSADSSSSWGQE---GHFFDL
DFLANDPMIPAALLPFQGSLIFQVEAVEVTPLSPEEEEEE----------AVADPDPGGD
-LAGEGEEDSTSASFLQSLSDLSITEGMDEAFAFRDDTSAASSDS--DSASYAEADD-ER
LYSGEPHAQAT-LLQDSVQKTEEESGGGAKGLQAQDG---------TVSWAVE-----AA
PQTSDRGAY-LSQRQELIS-----EVTEEGLALGQESTATVTPHTLQ-------------
------------------------------------------------------------
--------------VAPGLQVEVATRVTPQAGEEETDSTAGQESAAMAM-----PQPSQE
GISEILGQESVTA--EKLPTPQE--------------------ETSLTLCPDSPQNLKEE
GG-------------------------------------LDLPSGRKP-VAAATIVPRQA
KEDLTLPQDSA-MTPPLPLQDTDLSSAPKPVAAATIVS----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------QQAEEGLTLPQDSVMTPPLPLQDTELSSAPKPVA------AATLVSQQAEEGL
TL-PQDSAMT------PPLPLQDTD-L----------SSAPKPVAAATL--VSQQ-AEE-
------------GLTLPQDSAMTPPLP---------------------------------
-----------------------------------------------------------L
QDTDL-S-------------SAPKPV-------------------------AA---ATLV
SQQAEEGL----------------------------------TLP---------------
---------------------------------------------------------QDS
AMTPPLPLQDTDLSSAPKPVAAATIVSQQAEE----GLTLPQDSAM--------------
--------------------------------------------TPPLPLQDTDLSSAPK
PVAAATIVSQQAEEGLT-------------------------------------------
---------------------------------------LPQ--------------DSAM
TPPLPLQDTDLSSAPKPVA-----------------------------------AATP--
--V---------------------------------------------------------
------------SQQAEEGLT----------LP------------QDSAMTPPLPLQDTD
LSSAP-------------KPVAAATPVSQ-------------------------------
-----------------------------------------------------Q------
----AEEGLTLPQDSAMTAPLPLQDTGPTSGP-------EPLAVATP-QTLQAEAGCAP-
--------GTEPVATMAQ-------------QE--VGEALGPRPAPEEKNAALPT-----
----------------VPEPAALDQVQQDDPQPA-------------AEAGTPWAAQEDA
DS----------------TLGMEALSLPEPASGAGEEIAEALS-RPGREACLEARAHTGD
GAKPDSPQKETLEVENQQEGGLKPLAQEHG-P-----RSALGG-----------------
--ARE-----VPDAPPAACPEVSQARLLSPAREERGLSGKSTPEPTLPSAVATEASLDSC
PESSVG----AVSSLDRGCP-DAPAPTSAPTSQQPE------------------------
------------------------------------------------------------
------------------------------------------------PVLGLGSVEQPH
EVPSVLGTPLLQPPENLAKGQPSTPVDRPLG----PD--PSAPGTLAGAALPPLEPPAPC
LCQDPQEDSVEDEEPPGSLGLPPPQAGVQPAA---AAVSGTTQPLGTGPRVSLSPHSPLL
SPKVASM---DAKDLALQILPPCQVPPPSGPQSPAG------------------------
-----------------PQGLSAPEQQEDEDSLEE-------------------------
---------------------------------------------------------DSP
RALGSGQHSD--S-HGESSAELDEQDILAPQ--TVQCPAQA----PAGGSEETIAKAKQS
RSEKKARKAMSKLGLRQ--IQGVT----RITIQKSKNILFVIAKPDVFKSPASDTYVVFG
EAKIEDLSQQVHKAAAEKFKVPSEPSALVPESAPRPRVRLECKEEE--E--EEEEEVDEA
GLELRDIELVMAQANVSRAKAVRALRDNHSDIVNAIMELTM-------------------
----------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------PAATILGGEQ------R
DPHALT-PGPSPLTLAFLPSKPGTRPQPEGASWDAGPGGGPSAWADPAEGSPN--LLPEG
LHPQA------LPATLEPRIVMGEETCQA-PPSP---------------RAVLPALREQ-
-----------ELCSQDDPPVPSWSPDPEPYFTPPSTPTKATCTLLLSPGLHRDTW--DP
EAELL----DSLASSPSGSYVTADGDSGXX------XXXXXLSLLAPTEGLDFPSGWSLS
QPESVA--------------EEWEPPPAET---PSSESSLSGDSGSSWGQE---GHFFDL
DFLANDPMIPAALLPFQGSLIFQVESVEVTPLPAEEEEEE---------VAADTPAPAGE
-AAGED-EDSTSASFLQSLSDLSITEGMDEAFAFRDDTSAASSDS--DSASYAGADD-DR
LYSGEPHAQPSAEQEC------------------ADR---------AVFWAAE-----VP
E----G-EACLSQSQESIT-----GVMEEGLASSQEPAAAVTPHTGQATP--GLTP---Q
VDSVAPDSS---------------------------------------------------
-----------ESALLPLLDEDP-------------ISE---------------------
------------------------------------------------------------
----------------------------QELV------------------AAATLRPLQA
EGGNPLPQDSPKSAFPSPLDEDP-TLGIECVTAATLES----------------------
------------------------------------------------------------
--------------------------------------------------HEAEGGILLL
QDSPESSPPT--------------------------------------------------
---------------------------LQDEDPTPDPKSMA------AVTLGPLQAGGGT
LL-PQDSPKSS-----SPLSLQDAD-P----------IPGPEFMAAVTP--GSLQ-----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------TEGGTPLPQDSPESA--------
------------------------LL-----------------PLLDKD-----------
------------SISDLEAVAAATLRPLQAE-----------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------GGVPLPQD--------------PPE
SALPPLLDKDPISDLEVVAAATLRPLQ---------------------------------
------------------------------------------------------TKVRVP
-------------------------------LP------------QDSPESSPPSLQDED
PTPGP-------------KPM---------------------------------------
------------------------------------------------------------
-------------ASPDSSPPPLQDEG-----------------------------HIS-
--------GLEAVATLAS------------QE------AGGGKPVPKEWAA---------
------------APLSDPEPVALNQAPQDGPKPVAEAGELKP-----------QREGTGP
N-LDTKAPNRPT-----------------AALGPAEEGAPGLP-P----AEKEAQVPTGD
GAETCLPPEXXXXXKNQRARGPKAPTQGQG-P-----RSAPRG-----------------
--ARG-----APKTLCATYPEASQVQPQSPSREGRALGGKGTPASRLPTALVAEAQQGSC
LGSPAK----AMSSPKK------PGPSAPSSPQQ--------------------------
------------------------------------------------------------
-----------------------------------------------EP--VPGSGQRPL
ATPSLLSPSPPSHPRTPNRGPPSEPRSRLLD----PN--PSAPGA-------------SR
PHRGPRDDSMEGVEPLASRGPPQPRVGAQRVT----AASGTTQPRGAGQRVGLAPQPPLL
SPKAAPA---DAKEPASRTSPPCQVPPPSGSRGSRR------------------------
-----------------PQGPPASEQQADEDSLEEGERLGGSG--CWTSL----------
-----------------------------------------------GGWSHICPSPDSP
RAPGSGQHSD--S-HGESSAELDEQDVPAPH--A-QRPAQA----PTGSSEETIAKAKQS
RSEKKARKAMSKLGLRQ--IQGVT----RITIQKSKNILFVIAKPDVFKSPASDTYVVFG
EAKIEDLSQQVHKAAAEKFKVPSESLALVPESAPGPQLRPECEEEE--E---EEEEVDES
GLELRDIELVMAQANVSRAKAVRALRDNHSDIVNAIMELTM-------------------
----------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------MLLPEG
LSSQALSTEAPLPATLEPRIVMGEETCQA-LLSP---------------RAARTALRDRE
G-GHASPDPPPELCSQGDLSVPSPPPDPDSFFTPPSTPTKTTYALLPGCGPLGDAG--DS
EAELWDELLDSPPPSPSGSYITADGDSWAS------SPSCSLSLLAPAEGLDFPSGWGLS
PQGSMA--------------DERELHPAGTPEPPSSESSLSADSSSSWGQE---SHFFDL
DFLANDPMIPAALLPFQGSLIFQVEAVEVTPLSPEEE-EE----------AVADPDPGGD
-LAGEGEEDSTSASFLQSLSDLSITEGMDEAFAFRDDTSAASSDS--DSASYAEADD-ER
LYSGEPHAQAT-LLQDSVQKTEEESGGGAKGLQVQEG---------TMSWALE-----AA
PQTSDRGAH-LSQRQKSIS-----EVTEEGLALGQESTATVTPHTLQ-------------
------------------------------------------------------------
--------------VAPGLQVEAATRVTPQAGEEKADSTTGQASAAMAM-----PQPSQE
GISEILGQESVTA--EKLPTPQE--------------------ETSLTLCPDSPQNLKEE
GG-------------------------------------LDLPSGPKP-VAAASLMPQQA
EEDLTLPQDPA-VTPPLPLQDMDLSSAPKPVAAATTVP----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------RKAEEDLTLPQSPAVTPPLPLQDTDLSSAPKPVG------AASLVPQQAEEDP
TL-PQDPTII------PPLPLQDTD-L----------SSAPKPVAAATT--VPRQ-AEE-
------------DLT---------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------LPQ--------------DPTI
ISPLPLQDTDLSSAPKPVA-----------------------------------AATI--
--V---------------------------------------------------------
------------PRQAEEDLT----------LP------------QDPTIIPPLPLQDTD
LSSAP-------------KPVAAATTVPR-------------------------------
-----------------------------------------------------Q------
----AEEDPTLPQDSAMTPPLPLQDTGPTSGP-------EPLAVATP-QTLQAEAGCTP-
--------GTEPVATMAQ-------------QE--VGAALGPRPAPEEKNAALSR-----
----------------VPEPAALDQVQRDDPQPA-------------AEAGTPWAAQEDA
DS----------------TLGMEALCLPEPASGAGEEVAEALS-RPGWEACLEALVHTSD
GAKPDSPQKETLEVENQQGGGLKPPAQEHG-P-----GSTLGG-----------------
--AGE-----VPETPPAACPEVSQAWLLSPAREGRGLSGKSTLEPTLPSAVATEASLDSC
PESSVG----AVSRLDRGCP-DAPAPTSAPTSQQPEPVLGG-------------------
------------------------------------------------------------
-------------------------------CPDAPAPMSTPTSQQLEPVLGLGSVERPH
KAPSVLGPLLLQPPENLGKGLPSAPPDRPLG----PD--LSAPRTLAGAALPPLEPPAPC
LCQDLQKDSVEEEEPPGSLGLPTPQAGAQPAA---AAVSGTTQPLGTGPRVSLLPHSPLL
SPKVASM---DAKDLALQISPPCQVPPPSGPQSPAG------------------------
-----------------PQGLSAPEQQEDEDSLEEGKGEGRIE--VPWGLGQLDSSLELS
WAGGPLRWWGGGPRPHSHHGELALLPLALMWQQGQGPESPSPPPRSKRPSSHLSPSPDSP
RALGSGQHSD--S-HGESSAELDEQDILAPQ--TAQCPAQA----PAGSSEETIAKAKQS
RSEKKARKAMSKLGLRQ--IQGVT----RITIQKSKNILFVIAKPDVFKSPASDTYVVFG
EAKIEDLSQQVHKAAAEKFKVPSEPSALVPESAPRPRVRLECKEEE--E--EEEEEVDEA
GLELRDIELVMAQANVSRAKAVRALRDNHSDIVNAIMELTM-------------------
----------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------MSKLGLRQ--IQGVT----RITIQKSKNILFVIAKPDVFKSPASDTYVVFG
EAKIEDLSQQVHRAAAEKFKVPTEPSALVPESTPGPLVRPECEEEE--EE-EEEE-----
--ELRDIELVMAQANVSRARAVRALRDNQSDIVNAIMVSGRPPLTMSAP-----------
----------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
--------------MPGEAARAELLLPEAGGPGPRTDLSCDAAAAT-IPRGDR------Q
EPHVLT-PGPSPLTLTFLPDKPGTRPQPEGASWDAGPHGSPSAWADPAEGGPSPALLPEG
LAPQALPAEAPLPAALEPRIVMGEETCQA-LLSP---------------RAAQPALRDWE
GGGRASLNPPPESCSQDDPSVPSPPSDPDSYFTPPSTPTKTTYALLPGRGPHRDTW--DS
EVELLEELRDSPPASPSGSYITADGDSWAS------SPSCSLSLLAAPEGLDFPSGWGVS
PAGSVM--------------DERELHPAGPLGPPSSESSLSADSDSSWGQE---GHFFDL
DFLANDPMIPAALLPFQGSLIFQVEAVEVTPLPAEEEEEEEE--------EVSAPDPAGD
-LVGEGEEDTTSASFLQSLSDLSITEGMDEAFAFRDDTSGACSDS--DSTSYAGADD-ER
LYSGEPHAQPSALLPDSLQKAEEEDGAGAEGPEAQEG---------ATLWGPE-----AT
PQVSGGE-AHPTQSQESFS-----EISEEGPVVGQESAATVTPHSLQ-------------
------------------------------------------------------------
--------------AAPGLQMEAATWVSPQAGEEEADSTAGQAPTAVAT-----PQLSRE
GGSAALQQGPVTAET----------------------PPTPQEEASLTLCPDPPQNLKGE
G--------------------------------------PGLSSGPQP-M----------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------IAAMPMPPQAEE----SLPFS-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------RDCATAAPLPLPDAGPPLGQ-------EPVAAVTP-QALQAAAGCAP-
--------DTEPMASMAQ-------------EE--VGVTLGLRPAPDEKDAALPR-----
----------------GVEPPALDQFQQDDPEPGAGAEAPGASH----------------
-------------GDACPTLGTEAPDAPEPASGAGEELAEGLS-EPEWEACLEAQVQTGD
GAEAHSAPKEALVAENQREGGPKPPAQGHG-P-----GAAPQG-----------------
--SGE-----APEARPAACPEADQAPPLSPAREGRGP--ECTPGPRLPTAVATEAGLGSC
PESSAG----SASGLERGCP-EEPGGAPLS------------------------------
------------------------------------------------------------
----------------------------------------EPPSRQLEPALGLGSGEQPQ
AAPRAASPSPPQPSESPARGLPSAPQDRLAG----PD--SSTPGVLARASPPPLEPPAPC
LCQSPQEDSVEDEEPPGSPGLPPPQAGARPVA---AAVSGTSQPPGTGQRVSPASHSPLL
SPRAAPT---KAKDLALRISPPCQVPPCSGP-----------------------------
------------------QELPTSEQQEDEDSLEED------------------------
----------------------------------------------------------SP
QAPGSGQHSD--S-HGDSSAELDEQDISAPQ--TTQCPAQA----PTDSSEETIAKAKQS
RSEKKARKAMSKLGLRQ--IQGVT----RITIQKSKNILFVIAKPDVFKSPASDTYVVFG
EAKIEDLSQQVHKAAAEKFKVPSEPSGLVPESAPRPRVRPECEEEE--EEEEEEEEVDEA
GLELRDIELVMAQANVSRAKAVRALRDNHSDIVNAIMELTM-------------------
----------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
--------------MPGEATRAELLLPTGGGPGPRTVEPHDAAAST--PSGDS------S
IRGDLT-PGPVSIPLTFLPSKQGDRPQPEGASSDAGVGSTSSSRTALGECGPVVG-----
-LPRSLPEEPLTLEGLEPRVVMGEETNGS-GPRQAAAELPKEPLAAEPLMVTASELRDLE
G-RRAGPSPPPELLSQGDLPVPSPRLDPDPYFTAPSTPTKLACSYLFSHTLCLSEEPSDT
EAD----ILGSPPTSPSGSYITAEGGSWASSSSFSTSPSCSPNLLMETEGPDSPGNRDVP
LLYSNEEGGQESPLDGASDSDDTELLPSGPQDLPSSESSLSGDSGSSWSTGRREHPFPEA
GFPGSEPMIPATLLPFRGSLIFEADAVEIMLLPQEEALS---------------------
-RDSEGEDDSTSASFLQSLSEMSINEGVDEAFAFRDDTSAASSDSD--SVSYAGEED-ER
LYSEEPHAQPPAPLWLGSPESGE----NLADKKEELGSIC-----LPARWTEPA------
-------AMALTP-------------------------------------------QGLK
----EMDLKSIEVTTSHST----Q------------------------------------
---------------EVTDLESVVVSVTPQT-----------------------------
----------------------------------------LQEGVNLEPIAMK-------
--------TSQAVQEGVDLEPIAT--------K----------------------T----
-------------------SQAVQGVDLEPIAMKTSQAVQEGVDLDPIAMKTSQ------
---AVQEGVD--LDPIAMK-----------------------------------------
-----------------TSQVVQEGVDLEPI-AM------------KTSQTIQET-----
------VGQEPIATIS-QTTEEAVDLEPVIMKT---------------------------
-------------S---------QV------------------------------VQQTV
DLESIA--TM------ISQTIEEAEDIEP---------IATMT-----------------
-SQTIQETVGQEPIAII---------------------SHTIEEAVD-LEHIVMMTS---
-----------------------------Q-----TIEEAEDIEP------IAVMTSQTI
QETIDVE-------------PIAI-----------KT-----SQTIEEAIGQEPIAMNIS
QTIQETLDVESIAMKTSQTIEEAVDLEPAAMISQT-IEEAVDVEPVATKTSQTIQAAGLK
PIAVTSQALQETV--ELEPVAMKPSQ----------------------------------
-----TQKE----TIGLEPIAVAETPQTLQEVGLEFSAVTCQTLQEVSL-----KPIA-V
TPQTPQ--------------------------------------------EEPGFTLGSK
PITLEM----------------LQAD-------R------TQETPETLP-----------
-ARGQE--V------REEEKQEWPQ-DGESF----------------PGAEPSFPQREAL
PETWKLADG---QDQGAEGQKGLVGE-DEGARLDPLTEKSS----VVISKGSENSLSR--
---------DIDEER-----------------------RPPVSLECSLQCPPSS-RE---
--EEP--DL----------------GSEGS------VG----EQESSEQGSV--SPPKMD
LVSGPADAISASDEIGAPGPT------------S--GSRMEQ--------I-DVLGKEFL
AEVEF------------N-----VEENCPEP-AAQ----------------------K--
--------------------PSLDE-----------------------------------
-------ETPEPTG-APE--PASRAKESRGSPGVPEGPQLD--LARDAEQASFLG-RAEG
PSSPSP----------E---L-TDLRFVPKPPKTSIVASVSPVGTEE---------SHGP
KLLVERAP--------------SSLLSPTSRS----------------------------
PKEPRGAAEEKSALPRGKP--P----NAAGGQNTKLGKSQPRSA-APVAAFKEAQSPSSP
LILMPSPVAPQAPPSPEASSNKGPPLPLAQK--------Q------EG------------
-GRVEGAITSSARAVSGNLPPSSLCPSDPDTAAAR-------------------------
------------------------------------------------------------
------------------------------------------KVGSPRH---R-----S-
-----PRGQGLASPRTPTPKAVPYAKDQAPAGSPEVISNPCSRGLWAG------------
------------------------------------------------------------
---QAPLGGSGPQ-VVPKSPTPSQVPLGPVPGPGVWAPTLSRAGLAATRREEYGIRDVAP
PAGSRKSREGTERPPLQGSGQSRSSSSSEADPLSRCAELEDLRQ---AA-----------
------------------------------------------------NMALRPAAGALP
NHRGSRNDSE--S-NGESLPELEEPDN-SDPRTAPPQAQLA---HSVGS-EETINKAKQS
RSEKKARKAMSKLGLRQ--IHGVT----RITIRKSKNILFVISKPDVFKSPASDIYIVFG
EAKIEDLSQQVHKAAAEKFKVPAEPSPIITETVPGLGAKEE---S------D-EEEVDET
GLEVRDIELVMAQANVSRAKAVRALRHNNNDIVNAIMELTM-------------------
----------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
--------------MPGEAARAELLLPEADGPGPRTDLSCDAAAATTILGGDR------R
EPCALT-PGPSHLALTFLPSKPGARPQPEGASWDAGPGGATSAWADPAEGGPSPKLLPEG
LS-QALPTEAPLPATLEPRIVMGEETCQA-LLSP---------------RAARTALRDQE
G-GHTSLDPPPELCSQGDLSVPFPLPDPDSFFTPPSTPTKTTYALLPGSGPHGDAQ--DS
EAEMQDELLDSPPASPSGSYITADGDSWAS------SPSCSLSLLAPDEGLDFPSGWGLS
PQGSMA--------------DERELHLAGTPEPQSSESSLSADSSSSWGQE---GHFFDL
DFLANDPMIPAALLPFQGSLIFQVEAVEVTPLSPEEEEEE----------VEAAPGPGGD
-LAGEGEEDSTSASFLQSLSDLSITEGMDEAFAFRDDTSAASSDS--DSASYAEVDD-ER
LYSGEPHAQPT-LLQDSVQKTEEESGGGAEGLQVLEG---------TVSLALE-----PV
SQTSDRGAH-LSQRQESFS-----EVTEDGLALGQESTATVTPHTLQ-------------
------------------------------------------------------------
--------------VALGLQVEVATRMTPQAGEEEVDSTAGQAPAAMAV-----PQPSQE
GISEILGQESVTAEK--LPTPQE--------------------EASLTLCPDSPQNLK--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------EGGGLDLL
SG------------------------------------------------------PKPV
ATATLVLQQAEDGLTLPQDSAVTSPLPPQDTDLPSGP-----------------------
------------------------D-L----------PS---------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-GPEPVAITTLVPQQAEDA----------LT------------LPQDSA-----------
--------------------VAAATLVPQ----Q--------------------------
------------------------------------------------------------
----AEDGLTLPQDSAMTAPLPLQDTGPTSVP-------ESLAMTTP-QTLQAEADCAP-
--------GTESVASMAQ-------------QE--AGAALGPRPAPE-NIALPR------
----------------VPEPAALDQVQQDDPQPA-------------AEAGTPWAALEDV
GP----------------TLGLEAPHLPEPASGMGE-EVAEALPMPKRQACLGARVHTGD
GD---LPPKETLEAENQQGGGLKPPARACG-P-----GSALGG-----------------
--AGE-----VPEAPPAACPEVSQARLLSPAREGRGPSGKFTLEPRLPSAVATEACLDSC
PESSVG----AVCRLDGSCP-ETPAPTSAPTSQQL-------------------------
------------------------------------------------------------
-----------------------------------------------EPVLGLGSVEQPQ
EAPSVLGPQLLQPPENLAKGLPSLPLDRLLG----PD--PSIPGVLAEAALPPLDPPAPC
LCQDPQEDSVEDKEPPGSLGLPPPQAGAQPAT---VAVSGTTQPLGIELGVSLSPHSPLL
SPKVAPT---DAKDLALQISLPCQVPPRSGPQSPAG------------------------
-----------------PQGLSAPEQQEDEDSLEED------------------------
----------------------------------------------------------SP
RVPGSNQHSD--S-HGESSAELDEQDILAPQ--TAQCPAQA----PAGGSEETIAKAKQS
RSEKKARKAMSKLGLRQ--IQGVT----RITIQKSKNILFVIAKPDVFKSPASDTYVVFG
EAKIEDLSQQVHKAAAEKFKVPSEPSALIPESAPRPRVRLECKEEE--D--E-EEEVDEA
GLELRDIELVMAQANVSRAKAVRALRDNHSDIVNAIMELTM-------------------
----------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------MLLPEG
LSSQALSTEAPLPATLEPRIVMGEETCQA-LLSP---------------RAARTVLRDRE
G-GHASPDPPPELCSQGDLSVPSPPPDPDSFFTPPSTPTKTTYALLPGCGPLGDAG--DS
EAELWDELLDSPPPSPSGSYITADGDSWAS------SPSCSLSLLAPAEGLDFPSGWGLS
PQGSMA--------------DERELHPAGTPEPPSSESSLSADSSSSWGQE---SHFFDL
DFLANDPMIPAALLPFQGSLIFQVEAVEVTPLSPEEE-EE----------AVADPDPGGD
-LAGEGEEDSTSASFLQSLSDLSITEGMDEAFAFRDDTSAASSDS--DSASYAEADD-ER
LYSGEPHAQAT-LLQDSVQKTEEESGGGAKGLQVQEG---------TMSWALE-----AA
PQTSDRGAH-LSQRQESIS-----EVTEEGLALGQESTATVTPHTLQ-------------
------------------------------------------------------------
--------------VAPGLQVEAATRVTPQAGEENADSTTGQASAAMAM-----PQPSQE
GISEILGQESVTA--EKLPALQE--------------------ETSLTLCPDSPQNLKEE
GG-------------------------------------LDLPSGPKPV-AAASLVPQQA
EEDPTLPRDPA-VTPPLPLQDTDLSSAPKPVAAATIV-----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------PRQAEEDLT----------LP------------QDPAVTPPLALQDTD
LSSAP-------------KPVAAASLVPQ-------------------------------
-----------------------------------------------------Q------
----AEEDPTLPQDSAMTPPLPLQDTGPTSGP-------EPLAVATP-QTLQAEAGCTP-
--------GTEPVATMAQ-------------QE--VGTALGPRPAPEEKNAALSR-----
----------------VPEPAALDQVQQDDPQPA-------------AEAGTPWATQEDA
DL----------------TLGMEALCLPEPASGAGEEVAEAVS-RPGWEACLEALVHTGD
GAKPDSPQKETLEVENQQGGGLKPPAQEHG-P-----GSTLGG-----------------
--AGE-----VPEAPPAACPEVSQAWLLSPAREGRGLSGKSTLEPTLPSAVATEASLDSC
PESSVG----AVSRLDRGCP-DAPAPTSAPTSQQPEPVLGSCPDAPAPMSTPTSQQPEPV
LGSCPDAPAPMSTPTSQQPEPVLGSCPDAPAPMSTPTSQQPEPVLGSCPDAPAPMSTPTS
QQPEPVLGSCPDAPAPMSTPTSQQPEPVLGSCPDAPAPMSTPTSQRLEPVLGLGSVERPH
KAPSVLGPLLLQPPGNLGKGLPSAPPDRPLG----SN--LSAPGTLAGAALPPLEPPAPC
LCQDLQKDSVEEEEPPGSLGLPPPQAGAQPAA---AAVSGTTQPLGTGPRVSLLPHSPLL
SPKVASM---DAKDLALQISPPCQVPPPSGPQSPAG------------------------
-----------------PQGLSAPEQQEDEDSLEE-------------------------
---------------------------------------------------------DSP
RALGSGQHSD--S-HGESSAELDEQDILVPQ--TAQCPAQA----PAGSSEETIAKAKQS
RSEKKARKAMSKLGLRQ--IQGVT----RITIQKSKNILFVIAKPDVFKSPASDTYVVFG
EAKIEDLSQQVHKAAAEKFKVPSEPSALVPESAPRPRMRLECKEEE--E--EEEEEVDEA
GLELRDIELVMAQANVSRAKAVRALRDNHSDIVNAIMELTM-------------------
----------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------MGEETCGA-PAAP----------------SAAPELRDRE
G-GYADPGPPPNLCSQGDPPVPCPRLDPDSYFTPPSTPPKAACALLPGHGAWGSEA----
-EL----PWDSPPASPSGSYVTADGDSWAS------SPSCSLNMLA--DGPDAAPGWGLT
PLGDGLEQ-------------------RAPASPASSASSLSSDSCSSWGLE---EHVFDL
DFLANDPMIPASLLPFQGSLIFQVDAVEVTLLPSEEEEAE-------------VPAPAGD
PAAAEGEDDSASASFLQSLSDMSIVEGMDEAFAFRDDTSAASSDSD--SASYAGVDD-ER
LYSGEPHALPHGAIQLADDSRGD----GPEGLQLQEM------APPSGPGGSVAAPT---
HHTS-GGRVHLTAGQGPAAQKAEAPLSEGGVLSGQGPATTVTGEVGLERGSEPRAPAGPG
MGTEEAGAVPGPASVGRATLPPPPE-----------------------------------
---------------AVSATSGQDTVALAHT-----------------------------
----------------------------------------PQEGGGPTLCADSLETSGML
GNL--KEAAGPGLPSGQESTATAM--------AVPQCGEVDFVSPQEF-VSSAVPLTPHT
EAALTLPQESVSMAMPLLWQDASLPLGQEAVAMGTPLALQEERGCDGDTEPLTSAAALAQ
QEAGVTSGLVPAADSGAVASPPPEPRQVDLTLG--L--ERLTLDQVWQDE----------
---------------------VGLTLDLGPG-AE------------AVTPGAAWEDTRLP
PGTKAPDPPVPGPDQGEKGAAEGLS-APTCLQT---------------------------
---------DDGAE---------PHLPLE-ALDPPEPGS--------------DQAEEGV
AKKQTAEGLS------VPTCLQTDDGAEP---------HLPMKEALVSPEPGSDQAEEGS
AEERVAEEGGGEGLLVPTCLQTD-----------DGAEPHLPLEALYRPEPGSDRAE---
-----------------------------EGVAGEGVTEEGAAEG------LSVPTC--L
QTDDRAE------------PHLPLEALDPPEPRSDQAEEGVTEEGAAEEGAAEG--LSVP
TCLQTD-----------DRAEPHLPLETLD-----------PPEPGSDQAEEGAAEEGAA
EGLLVPTCLQTDD--GVEPHLPLRALDSPEPGSDQAEEEVAGEGVTEEGAAEGLLVPT--
-CL--QRDEGAEPHLPLEALDSPEPGSDQAEEGAAEGLLVPTCLQRDDRAEPHLPMKEAL
DSPEP------------------------------------------------GSDQAEE
EVAGEGVTEEGAAEGLSVPTCLQRDD-------RAE----PHLPLEALD-----------
-----------SPEPGSDQAEEEVAEKGVTEEGAAEGLSAPTCLQTDDGAEHQLPLEEAL
DSPEA---------RSGW---GEEGAAEEGVVEQGVAEGLSAPTCLQTDDGAEPRLPLEA
LDSPEPESDQVEEEAAE--------------EGAVEGLSAPTCLQTDDWAEPQLPLEQAL
DTSGPGSGW----------------GEEGM------A-----EEEAAEGLLVPTCLQT--
-DDGA-KPHLPLEALDSPEPGSDQVEEEVAEEGVEEGLSMPTCLQTD-DGAKPHLPLEAL
DFPEPGSDQVEEGVAGDGSAEGLLMPTCLQTDDGA----------------------EPH
LPLEALD------------FPELGSDQVEEGVAGEGSAEGLL---AP-ICLQTDDGAEPH
LPIKEALVSPEPGSDQAE--EGS-AEEGVAEEGGGEGLSVPTCLQTDDRAERHL-PLQEA
LGSPEP----------E---S--DQAEEGGGEGLSVPTCLQ---TDD---------RAER
HLPIKE-----------------ALSSPEPGSDQAEEGSA--EEGGGEGLSVPTCLQTDD
GAEPHGPLEEASAVPSLGSKGPKSTEHRPGRRLKGLGTARGSGSH---------------
---GARP---------AACSEVGQAQPLSPPEDARASEPR------LGT----S------
----LGCPAGTTSRLGGDWP-ETPAPTEPVLSVGD-------------------------
------------------------------------------------------------
----------------------------------------GEGAGSRGLHLGRATEEWEP
AAPSVLDHTGSQPPETPAQDLHAAPRDRAPA------SDPSTTSFCTGAAPQRSMPPAPC
LCQEPREDSLGEGAPPGSASTER--LGAAQWA--VAAVSGNLVP-PTGRRASLSLHAPLL
SPQAAPVGGAHAKDPASLISPHCQVPPGSGPRTLAS------------------------
-----------------PPGRAAAEPPED-------------------------------
---------------------------------------------------PDCVDEASP
HARGSGRRSH--SPAQCSAPELEEQDPSAPR--TAPCPSQA---PTAGSNEEAIAKAKQS
RSEKKARKAMSKLGLRQ--IQGVT----RITIQKSKNILFVITKPDVFKSPASDTYVVFG
EAKIEDLSQQVHKAAAEKFKVPAEPLALAPESAPGPXXXXXXXXXXXXXX----------
---XXXXTLPSPA--------TPPSRWTSQG--------WSCETLS----W---------
----------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
--------------MPGEAARAELLLPGGSRAGLSTDLSCDAVAAT-IPGGDL------Q
QPQALT-PGSSPLALSFLPSKPGARPQPEGASWDAGPGGASSAWADAAEGGPSPTLLPEG
PPSQALSPEA-LPSSLEPRIVMGEETCQA-PASP---------------WAAGPALRDRE
G-GRAGLHPPPEPCSQGDPPVPSPPPDPDSFFTPPSTPTKTTYSLLPSH---GDSW--DP
EPE-----LDSPPASPSGSYITADGDSWAS------SPSCSLSLLALAEGLDFPSSWGLS
PPGSVV--------------DEGERSPPRPPGAPSTESSLSADSSSSWGQE---GHFFDL
DFLANDPMIPAALLPFQGSLIFQVEAMEVTPLHA----------------VGAAPAPGRD
-LAGEGEDDSTSTSFLQSLSDLSITEGMDEAFAFRDDTSAASSDS--DSASYAGADD-ER
LYSGEPHAQPSAPFLEGTQKAEQECRAAAEQLRGPEG---------PESCGLEAAGATPT
PRVSERE-ACLTQSQDRME-----TAGEE-HTPGQEATASKTPPALQAAP----------
------------------------------------------------------------
-----------------GPQAAPGPHITPEAEEEEEDSTAGGAPSQAAPGPHITPEAKEE
-----------------------EEEDSTA------GGAPSQAAPGPHITPEAEEEKEDS
S-------------------------------------AGGAPSPAAP---GPQLTPEAE
EED----E------------DDD-STAGGAPSQAAPGP----------------------
-----HITPEA------------KEEEEDSSAG---------------------------
------------------------------------------------------------
-GAPSQAAPAPQL-----------------------------------------------
------TPEAEEAAT----------------GPQLTPEAEEEEEEDSTAGGAPSQAAPGP
HITPEAEEEKA-----APDP-----------------QL--------TP--EAEEEEEE-
------------DSTAG-------------------------------------------
----------------GALPQA--------------------------------------
------------------------------------------------------------
----ALGPQLTPEAATGPQLTPEAKEEDS--------TTGGA------------------
------------------------------------------------------------
-------------PSQAAPGTQLTPEAKEEEE----EDST-----AGGAP--FQAAPGPQ
LTPEVKEEEEEDST-----AGGAPSQVAPGPQLTPEAKEEEEDSTAGG------------
------------------------------------------------------------
------------------------------------------------------------
----------------ALSQAALGPQL---------------------------------
--TPEAEEEEEDSTAGRAPAPRAL-------------------------SQPCQERAGAA
LGPDPG-------------------TAEGPPSLQDEAGHTSCPDPPQNT-----TAAGPD
LPSGP-------------GPVAAAPPV---------------------------------
---TP----------------QALLPDC--------------------------------
----------------------------------------------------PTAGCPA-
--------GPEAVAASGLQAAGTKDTEPMTSQN--QAVALRARPALENKSTAPPA-----
----------------GPALPVAAQAQQDDPELAAEAE----------------------
--------------DASPTSGMEAPGPPGPAFDIGGA-----AAAPEREESSGAHVHTSD
E------------AEKRRRGGPKPLAQGHGGP-----RSAPPG-----------------
--AGE-------------TPGVSQGQPPSPAREGKRPSGKSTSRPKLPAAKLAEAGLGSC
SKAPAR----AASRLGRGCP-EEPAPATPC--RQP-------------------------
------------------------------------------------------------
-----------------------------------------------EPVLGLGR---SQ
VVPSVLSPTPPQPPEDPARALPTAPQHRHPG------------------------SLGPC
LCQHPQD-SLDDEEPPDSPAPPTSRARAQRAT---AAVSGTPRLPGPRQQAGLAARSPLP
SPEAAPT---DAKDVASGPLPPRQVPPPPGPSSLAD------------------------
-----------------APGAPAPEPQEDEDSPEED------------------------
----------------------------------------------------------SP
RAPGSGQHSD--S-HGESSAEPDEQDVSAPQ--PAQCPAQA----PASSSEDTIAKAKQS
RSEKKARKAMSKLGLRQ--IQGVT----RITIQKSKNILFVIAKPDVFKSPASDTYVVFG
EAKIEDLSQQVHKAAAEKFKVPSEPSALVPESLPGPRVRPECSGRY--H--LVPPQVDEA
GLELRDIELVMAQANVSRAKAVRALRDNHSDIVNAIMELTM-------------------
----------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
--------------MPGEAARAELLLPEAGRPGPRTDLSCDAAAAT-IPRGDQ------Q
EPHVLS-PGPSPLALTFLPSKPSTRPQPEGASWDAGPYGAPSAWADPAEGSPSSVFLPEV
LPPQVLSPEAPLPATLEARIVMGEETCQA-LPPP---------------RAAQPVLRDWE
GGGHESLNPPPESRSQGDPSVPSPPLDPDSYFTPPSTPTKTTYTLPHGQGTHRDTW--DS
EAELLDDLLDSTPASPSGSYITADGDSWAS------SPSCSLSLLAPTEGLDFPSGWGLS
PTGSLM--------------NERELHPAGPSGPPSSESSLSADSDSSLGQE---AHFFDL
DFLANDPMIPAALLPFQGSLIFQVEAVEVMPLPPEEEEEEE---------KAGAPDLAGD
-LAGEGEEDSTSASFLQSLSDLSIMEGMDEAFAFRDDTSGASSDS--DSTSYAGAED-ER
LYSGEPHAQSTTLPQDSVLETEEESRGGVKGPQAQEV---------AAPWGLE-----AT
PLVSREEIH-LTQSQESIE-----ETSEEGLIIGQESAATVTTHTVQ-------------
------------------------------------------------------------
--------------AAPGLQLDAVSRVTLQAGEEEAASATGQAPTV--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------GAM----------
---PQHQQKG------TSTPLNQE------------------------------------
------------------------------------------------------------
---------------------------------------------------PVTAE----
----------------------------IP------------------------------
STLQE---------EASFTLCPNPPQNL--------------------------------
------------------------------------------------------------
------KEGRPGLPSGPQPVAAVTPGSQQTEE----EHTLPQK-----------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------C-----------------
------------------------------------------------------------
---------------AVAAPLSLQDADSPSGQE-------PVAMVTP-QALQAEADCVP-
--------GTEPMTSMDQ------------EVE--VGVALELRPAPEERDRVLPR-----
----------------DLEPPALDQAQQDDPEPT-------------AEAEAPWASHEDA
CA----------------TLGVEAPGPPKSASAAGGELAEGLS-VPKWEACLEAQVYTGD
VAEPHSVPNKALGAENQREGGPAPPAQGHG-P-----GAEPQD-----------------
--AGE-----APKACPAACPEVHQAQPLNPATEGRGPSGEVTPQPRLPTAVDTEACLGSC
PESPAE----ATSGLDRGCP-EDCAPVSAPSSQQL-------------------------
------------------------------------------------------------
-----------------------------------------------EPVLGLGSGELPK
EVPRTLSPSSPPSGGYGARGPPSAPQDKLPG----PD--TSTPGVLAGASPPPLELPSPC
LCQGPQEDSMGDKEPPG---LPPPQAGALPA---AAAVSGILQPPGAGSRVSLLSHSP-L
SPKAAPM---DAKDLALLISPPCQVPPRSRTRSPAN------------------------
-----------------PQGLPASEQQEDEDSLEED------------------------
----------------------------------------------------------SP
QAPGSGQRSD--S-HGESSAELDEQDTSAPQ--TTQCPAQA----PTGSSEETIAKAKQS
RSEKKARKAMSKLGLRQ--IQGVT----RITIQKSKNILFVIAKPDVFKSPASDTYVVFG
EAKIEDLSQQVHKAAAEKFKVPSEPSALIPESAPRPRVRPECEEEE--D--EEEEEVDEA
GLELRDIELVMAQANVSRAKAVRALRDNHSDIVNAIMELTM-------------------
----------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
--------------MPGEAARAELLLPEADRPGPRTDLSCDAAAATTILGGDQ------R
EPCALT-PGPSHLALTFLPSKPGARPQPEGASWDAGPGGVPSAWADPAEGGPSPKLLPEG
LS-QALPTEAPLPATLEPRIVMGEETCQA-LLSP---------------RAARTVLRDQE
G-GHASLDPPPELCSQGDLFVPFPPPDPDSFFTPPSTPTKTTYALLPGSGPHGDAQ--DS
EAEMQDELLDSPPASPSGSYITADGDSWAS------SPSCSLSLLAPDEGLDFPSGWGLS
PQGSMA--------------DEQELHHAGTPEPQSSESSLSADSSSSWGQE---GHFFDL
DFLANDPMIPAALLPFQGSLIFQVEAVEVTPLSPEEE-EE----------VEAAPGPGGD
-LVGEGEEDSTSASFLQSLSDLSITEGMDEAFAFRDDTSAASSDS--DSASYAEADD-ER
LYSGEPHAQPT-LLQDSVQKTEEESGGGAEGLQALEG---------TVFWALE-----AV
SQTSDREAH-LSQRQESIS-----EVAEEGLALGQESTATVTPHSLQ-------------
------------------------------------------------------------
--------------VALGLQVEVATRMTPQAGEEEVDSTTGQAPAAMAV-----PQPSQE
GISEILGEESVTAEK--LPTPQE--------------------EASPILYTDLPSGPEAV
VAATLVPQQAEEG-----------------------------------------------
---------------------------LILP-----------------------------
------------------------------------------------------------
-------------------------------------------QDSAVTPPLPPKDTDLS
SG------------------------------------------------------PEPV
VAATLVPQQAEEGLTLPQDSAVTPPLPPQDTDLPSGPEPMA------AATLVPQQAEEGL
IL-PQDSAVT------PPLPPQDTD-L----------PSGPEPVVAATL--VPQQ-AEK-
------------GLT---------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----LPQDSVVTSPLL-------------------------------------------
------------------------------------------------------------
-------PQDTDLLSGPEAVVAATLVPQQAEE----GLILPQDSAVTPPL--PPQDT---
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------D--------------------------------------------------
----------------------------------------------------------LP
SGPEAVVAATLVPQQAEEG----------LT------------LPQDSAVTPPLPPQDTD
LPSGP-------------EAVVAATLVPQ----Q--------------------------
------------------------------------------------------------
----AEEGLTLPQDSAMTAPLPLQDTGPTSVP-------EPLAVATH-QTLQAEAGCAP-
--------GTESLASMAQ-------------QE--VGAALGPRPAPEENIALPR------
----------------VPEPAALDQIQQDDPQPA-------------AEAGIPWAALEDA
GL----------------TLGLEAPHLPEPASGVEE-EVAEALSMPEWEACLGARAHTGD
GD---LPPKDTLEVENQQGGGLKPPAREYG-P-----RSALGG-----------------
--AGE-----VPKAPPAACPEVGQAQLLSPAREGRGQSGKSTLEPRLPSAVATEACLDSC
PESSVG----AVSRLDRGCP-EAPAPMSAPASQQP-------------------------
------------------------------------------------------------
-----------------------------------------------EPVLGLGSVEQPQ
EAPNVLGPDLLQPPENLAKGLSSVPLDGLLG----PD--PSVPGVLAEAALPPLDPLAPC
LCQDPQEDSVEDKEPPGSLGLLPPQEGAQPAT---VAVSGTTQPLGIGLGVSLSPHSPLL
SPKVAPT---DAKDLALQISLPCQVPPRSGPQSPAG------------------------
-----------------PQGLSAPEQQEDEDSLEED------------------------
----------------------------------------------------------SP
RVLGSNQHSD--S-HGESSAELDEQDILAPQ--TAQCPAQA----PAGGSE-TIAKAKQS
RSEKKARKAMSKLGLRQ--IQGVT----RITIQKSKNILFVIAKPDVFKSPASDTYVVFG
EAKIEDLSQQVHKAAAEKFKVPSEPSALVPESAPRPRVRLECKEEE--E--EEEEEVDEA
GLELRDIELVMAQANVSRAKAVRALRDNHSDIVNAIMELTM-------------------
----------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
--------------MPGEAARAELLLPEAGRPGPRTESSCDVAVAT-TPRGDR------L
EHCALT-PGPSTLALEFLPSKPGARPPPEGASWDAGPGGTPSAWAVPTEGSPSLG-----
-SPEAQPASGPPPTTLEPRIVM--------------------------------------
--------------------------DPDSYFTPPSTPTETTSALLLGPGPRRE-----A
PAE----PGDSPPASPSGSYITADGDSWAS------SPSCSLSLLAPAEGLDVPSGWGFS
PPGSLA--------------DEQELPPAGPPGPPSPESSVSADSSSSWGQE---GHFFEL
DFLANDPMVPAALLPFRGSLIVQVEAVEVTPRAPEE--------------EEEVPVPGGD
-PAGEGEDDSTFASSLQSLSDLSITEGMDEAFAFRDDTSAASSDP--DSASYAGADD-ER
LYSEEPHAQPAALLQD----TPGE----------------------PAP-----------
-TVSAGVASPASESREPGA-----RVPEMGQAST--------------------------
------------------------------------------------------------
---P------PAAQETPGL-----TGESPWTWGEDMGSISGLVPAAA---VTAQPQWEDD
GAALGPESWTSPEEGTLIPGPDSLQ------------------------------NLEGE
AGQGPESEATP-----------------------LSLQDTGLPSGQAL-AATVSPVPQPG
DTDRTLHQGPDCEATPVSLQDAALPSSQGTPAKARPETLRVDAGYV-PGIDPVVTA--AQ
QGGRVTSELRP------------APEERDTSCTGGLGPPA--------------------
------------------------------------------------------------
----------------------------------------------RD------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------QAQLDGLEPAADTGVPWT
SWGTSKPATEA-------------------------------------------------
----------LDSPKPATEATDPLEALQHPRPATDA------VEC---------------
-----------PGSDTEDTNCPKPVMETT-------------------------------
------------------------------------------------------------
ECTESATEATECPPSVTEATE--CLESGTE---------APEH----SKP-------SME
ASECPEHAM-EAPKCTKPANEALELLEPTSE-----------------------APEYPE
SATEALEHS---EPALETLEHSEPATE-----------------------VL--------
----------------------------ECP---DPATEVLEH--SEP------------
------------------------------------------------------APEA--
--LESPEPAME---APELPEPDTGAPECPEPAMEAPGYSEPATETPES-PEPAME-----
--------VLDHSEPAPEALECPEPAMEAPVYSEPATETLECPEPAMEAPEHSEP-----
-------------------------------------------------------AMETP
ESPEP----------------AMEAPECPQPAMEVLEHSESSMETPKHSEFAMEAPEDPE
PATEAPEHSEPATE-TLECPEPATEAPEHSECATETLECPEPATEAP-EHSEPATETLE-
--------CPEPATEAPE------------HSE--PATETPECPEPATEAPEHSEPATEA
PEHSEPATETPECPEPATEAPELSVPATEAPEATTEAQECSQPATEALKCPKPATEAPGL
SEPATEALEYSEPATGPPGPAMEATDPP-KLASIREEVAEGLL-APKQETCASACVFAGD
GVEPHFPPKEDPGGENQGAGGL---------------RSTPHS-----------------
--ARKAPGDSGPEVHLAALPEVSHTWPQNPAEEGR-----ANPEPRSSVAVASEAGLASC
SESPPR----SVARPGRGCP-EEPAPTIPAPSWRL-------------------------
------------------------------------------------------------
-----------------------------------------------EPMLGPGSGVRAQ
VAPGSPSLSPPQAPRSPNRGLPSMTRDRPLG----PE--PAAPGVPTEAAPCPMAPLMPC
PCQGPREDSTEAKEPPGSPGLQPPRAGAQRAV--A-ASSGTTKPPGAGHRVSLPPHSPLF
SPKTAPTGDTHAKDQAWRISTPCQVPP--------G------------------------
-----------------PQGLPAAEQQDDQDSLEED------------------------
---------------------------------------------------------SPP
RAPGSGQHSD--S-HGESSAELEEQDLSGAQ--TAQCPTQV---PAGGSSEETVAKAKQS
RSEKKARKAMSKLGLRQ--IQGVT----RITIQKSKNILFVIAKPDVFKSPASDTYVVFG
EAKIEDLSQQVHRAAAEKFKVPTEPSALVPESAPGPLVRSGCEEEE--EE-EEEEEVDEA
GLELRDIELVMAQANVSRARAVRALRDNQSDIVNAIMELTM-------------------
----------------------------------------------

MPSRQPGKCGGGGEVKGQINELPRDLETDPSGLPSLVRSRRLHPWLPWRQEAVATETDDC
QDQPITPELQLQGSPFGWRHRAGRGPLPPQALHLLLGQ--RSHRSPKRSEHSRIPTTSPI
SHNQ-GSGGVPASSRPRANATLRLLLPEADGPGPRTDLSCDAAAATTILGGDR------R
EPCALT-PGPSHLALTFLPSKPGARPQPEGASWDAGPGGAPSAWANPGEGGPSPMLLPEG
LSSQALSTEAPLPATLEPRIVMGEETCQA-LLSP---------------RAARTALRDRE
G-GHASPDPPPELCSQGDLSVPSPPPDPDSFFTPPSTPTKTTYALLPGCGPLGDAG--DS
EAELWDELLDSPPPSPSGSYITADGDSWAS------SPSCSLSLLAPAEGLDFPSGWGLS
PQGSMA--------------DERELHPAGTPEPPSSESSLSADSSSSWGQE---SHFFDL
DFLANDPMIPAALLPFQGSLIFQVEAVEVTPLSPEEE-EE----------AVADPDPGGD
-LAGEGEEDSTSASFLQSLSDLSITEGMDEAFAFRDDTSAASSDS--DSASYAEADD-ER
LYSGEPHAQAT-LLQDSVQKTEEESGGGAKGLQVQEG---------TMSWALE-----AA
PQTSARGAP-LSQRQESIS-----EVTEEGLALGQESTATVTPHTLQ-------------
------------------------------------------------------------
--------------VAPGLQVEAATRVTPQAGEEKADSTTGQASAAMAM-----PQPSQE
GISEILGQESVTA--EKLPTPQE--------------------ETSLTLCPDSPQNLKEE
GG-------------------------------------LDLPSGPKP-VAAASLMPQQA
EEDLTLPQDPA-VTPPLPLQDTDLSSAPKPVAAASLVP----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------QQAEEDLTLPQDPAVTPPLPLQDTDLSSAPKPVG------AASLVPQQAEEDP
TL-PQDPAVT------PPLPLQDTD-L----------SSAPKPVAAATT--VPRQ-AEE-
------------DLTL--------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------PQ--------------GPAV
TPPLPLQDTDLSSAPKPVG-----------------------------------AASL--
--V---------------------------------------------------------
------------PQQAEEDLT----------LP------------QDPAVTPPLPLQDMD
LSSAP-------------KPVDAASLVPQ-------------------------------
-----------------------------------------------------Q------
----AEEDPTLPQDSAMTPPLPLQDTGPTSGP-------EPLAVATP-QTLQAEAGCTP-
--------GTEPVATMAQ-------------QE--VGAALGPRPAPEEKNVALSR-----
----------------VPEPAALDQVQQDDPQPA-------------AEAGTPWAAQEDA
DS----------------TLGMEALCLPEPASGAGEEVAEALS-RPGWEACLEALVHTSD
GAKPDSPQKKTLEVENQQGGGLKSPAQEHG-P-----GSTLGG-----------------
--AGE-----VPEAPPAACPEVSQAWLLSPAREGRGLSGKSTLEPTLPSAVATEASLDSC
PESSVG----AVSRLDRGCP-DAPAPTSAPTPQQLE------------------------
------------------------------------------------------------
------------------------------------------------PVLGLGSVERPH
KAPSVLGPLLLQPPENLGKGLPSAPPDRPLG----PD--LSAPGTLAGAALPPLEPPAPC
LCQDLQKDSVEEEEPPGSLGLPMPQAGAQPAA---AAVSGTTQPLGTGPRVSLLPHSPLL
SPKVASM---DAKDLALQISPPCQVPPPSGPQSPAG------------------------
-----------------PQGLSAPEQQEDEDSLEE-------------------------
---------------------------------------------------------DSP
RALGSGQHSD--S-HGESSAELDEQDILAPQ--TAQCPAQA----PAGSSEETIAKAKQS
RSEKKARKAMSKLGLRQ--IQGVT----RITIQKSKNILFVIAKPDVFKSPASDTYVVFG
EAKIEDLSQQVHKAAAEKFKVPSEPSALVPESAPRPRVRLECKEEE--E--EEEEEVDEA
GLELRDIELVMAQANVSRAKAVRALRDNHSDIVNAIMELTM-------------------
----------------------------------------------

------------------------------------------------------------
-----PSAVPAHAHSLTRAGRGRGRA---------------------------A--AVDT
RTE--RGNQGRRQAMPGEAARAELPLPEADGTEPRTDLACDVPAVT-ILGGEQ------Q
EPRNLI-PAPSPLALAFLPSKPGARPQPEGASWDAGPGGGPSSWADPAEGGPNSALLPEG
LHPQA------LPTALEPRIVMGEETCQA-PPTA---------------RAALPVLREQ-
-----------ELCPQDDPAVPSRAPDPEPYFTPPSSPTEATYTLLLNRGLYKDAW--DP
EAE----LLDSLASSPSGSYVTADGDSGTL------SPSCSLSLLAPTEGPDVPSGWSFS
QPELVA--------------EEWEQHPAET---PSSESSLSGDSGSSWGQE---GHFFDL
DFLANDPMIPAALLPFQGSLIFQVESVEVTPLAPEEEEEEE----E---VAPDSLAPDGD
-VAGEDEQDSASASFLQSLSDLSITEGMDEAFAFRDDTSAASSDS--DSASYAGADD-DS
LYSGEPHAQPKARG----------------------------------------------
-----TGEACLSHSQDSVT-----GITEVGLASSQEYAATVTSHAGQVTN--KVTTQVGA
E---EVDSVARGIPVTQVPAYPSQNR-SAALGRPPRATEAE-------------------
-------------------------------------------PALR-------------
---------------------------------------------EAAGCPEL-------
---------------------------------TGPQGTPGLLEGLES-VAAAMLGSQQA
EGGTPLPQNCLESALPPLLDEDPI-SDLEFVAAAMLESEEA-GDV---------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------TPLLPDSPESSSHPSLQDVDPTSGPESLA------KATPGPLQVGGGM
PL-LQDSPETE-----LPPP-LDED-P----------TSGHESMAVAVL--GPLQ-AEG-
------------GVLLSQDFSKSPPPSLQD------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------KDPISSPVAMAVVMPGSQEAEG----GVPLPQNSPEAPLP--L-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------EDKNPDLGPNNMAAAIPGPLQA--------------------------------
-------------------------------------------------------KQGTL
-------------------------------LP------------QD-LLEPSPLLLDGD
------------------------------------------------------------
------------------------------------------------------------
----------------------------------STLGPESVAVATP-VALKTEVGCTA-
--------GSK-------------------SVE--LGVASGPKPVPKEWVTVPPG-----
----------------DPEPVPLNPVPQGGLKPEAEAVSFAPRGR---------------
--------------EAGPILDEEAPRPPKAAHSLGEEGALGLL-PAEPETCPEPQAPMGK
GAETGLPPGVAPGPKNQRDRGPKPLTQGHG-P-----KSVPRG-----------------
--ARA-----APKALHTACPKVGWAQPSSPGREGRALGSKGTP------ALAAGAQHSSC
PGAPAG----AVSRLDGDSP-REPSSPAPGNG----------------------------
------------------------------------------------------------
--------------------------------------------------------QQA-
-------PATPPLPRPLARGPPSASHTRLLD----PN--PSAPGA-------------SR
PRRSPREDSVE-EEPLVSRGPPPPRVGAQRTT----AASGTTQPRGAGQRFSLATQPAPL
SPKAAPP---DAKEPASRTSPPCQVPPSLGSRSPHG------------------------
-----------------PLGLPASEQQGEADSLEEGEGQ----PS------------CWA
PRGGCRPGLLT---------------------------------------RPVRPHAYSP
RALGSGQQSD--S-HGESSAELDEDTAA--P--HMQRPAQA----PTGSSEETIAKAKQS
RSEKKARKAMSKLGLRQ--IQGVT----RITIQKSKNILFVIAKPDVFKSPASDTYVVFG
EAKIEDLSQQVHKAAAEKFKVPSESLALIPESAPGPQLRTECEEEE--E----EEEVDES
GLELRDIELVMAQANVSRAKAVRALRDNHSDIVNAIMELTM-------------------
----------------------------------------------

------------------------------------------------------------
---------LPLALRSAWRGGARLLGLIALTS----ST--PPPIRGAVAELATLSALTDR
GTERQGDQQAHVQAMPGEAARAELPLPEAGGPGSRTDLSCDAAIAT-ILKGDQ------R
EPLPLT-PGPSPLALAFLSSKPGARPQPEGASWDAGPSGAASTWVDPAEGSPSPGVLPEG
LPLQPLPAEVPLPTTLEPRIVMGEETCQV-TPLP---------------RAAWPVLRDRE
G-GHMALHPPPELCSQGDPPVPSPPPDLDSYFTPPSTPTKTTYALLPDHGPHRDTW--DL
EAELLDELLDSTPASPSGSYITADGDSWAS------SPSCSLSLLAPAEGLDFPSDWGLS
PSGSVV--------------DELEPQPTEAPEPPSSESSLSTDSSSSWSQE---GHFFDP
TFLANDPMIPAALLPFRGSLIFQVEAVEVTPLPQEEEEEE---------VVAGAATPDGD
-LAGEGEDDSTSASFLQSLSDLSIIEGMDEAFAFRDDTSAASSDS--DSASYAGADD-DR
LYSGEPHAQPSAQNTEQEHRSR------------------------ATFQGTE-----FM
PQISEQ-ETCLTNSQESIA-----DIAEEAPTLGIESEATVTLPDLQ-------------
------------------------------------------------------------
--------------EAPGPQMEGATTVTPRVGNKEVDSVAQQAPRAL-------PEPCRK
GMGTSSGCKPVTV----------------------ESILDLQEEASPTLCPILPANLKEG
G--------------------------------------QGLPSTLEY-VTVASVRPQKA
EGGITIPQDHPMTLPPFLQ-CVDPTS----------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------------GPESV
AVVTLRLQQDEGCVIALQEAPVASPLPLQSTDPTSGPESRA------VATCGPQQAKEGT
TA-PQDSPMA------SSPPPQGSE-P----------TSDPEPEAVVTL--GSQQ-AKE-
------------GTTAPQDSPMASSPPPQGSD----------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------PTPDPESELAAILEPQQAKE----GVTIPQLAPVASPS----------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----PLRSLDSILDLQPVATATLESQQAKGS-----------------------------
------------------------------------------------------------
-----------------------------------------TTVPQDTFVVAPPSLQGTD
------------------------------------------------------------
------------------------------------------------------------
---------------------------STS-------EPELIVQD-TSPALQRETCYTP-
--------EIKPSASEAH-------------QE--LGVALGPKPVPEEQDSEPTL-----
----------------DSALTTSNQAQQNGSQPAVKADNAGAPEES--------------
----------------CPTLST---KVSEPISCMGEKVAESIP-ALRQG----AHLEAHG
GVKTCSPQREAPGAKNKRGRCPKPLGQGNG-S-----KSASQG-----------------
--AGK-----TSKAQSASCTEVSQTQL----------MSLDTLGPKLPVALSVQARLGSC
PDSPAR----ATCTLSGVHS-EETARSA--------------------------------
------------------------------------------------------------
-----------------------------------------QSFEQLEPVLGLGSRDQPQ
TTPGALNPSPA----NSVSDLPTTPQGRSLD----PD--PPASNDLNRASQTSPGPPASC
LCPTPQKASVEEEEPSASRGLMP-RAGAQGTA--AITTSGSTMPLGARHRVSLSPHST-L
NPKVTPT---DAKDLACIISSPCQVPPPSGTQNPSG------------------------
-----------------PRGFPAHQ-QEDEDSLEEGKSMWGPGSGN--------------
-------------------------------------------LGNSKRPSYLTPFPDSQ
RAPGSGQHSD--S-HGESSAELDEQEIP-SQ--KAQCPAQG----PTGSNEETIAKAKQS
RSEKKARKAMSKLGLRQ--IQGVT----RITIQKSKNILFVIAKPDVFKSPASDTYVVFG
EAKIEDLSQQVHKAAAEKFKVPSESSALVPELAPGPRVRPQCEEQE--E---EDEEVEEA
GLELRDIELVMAQANVSRAKAVRALRDNHSDIVNAIMELTM-------------------
----------------------------------------------

------------------------------------------------------------
---------PAHAHSGRW---AGGAALTSSTLRSPSPP--AEGRWPLRLRR--AAVRTDG
PRDR-GTRRALVEAMPGEAARAELPLPEASGPGPRTELSCDAAAAT-ILREDR------Q
EPHALI-PEPSSLTLTFLPSKPGARPQPEGASWDAVPGGAPSAWADPAEGSPNPTL-LSE
-GPLPQPPEGPLPVTLEPRIVMGEETCQA-PQSP---------------RAGLPVLRDQE
G-GLTNLYPPPELYSQGDPPVPFPPPDPDSYFTPPSTPTKTTYILLPSHGPHRDTW--DP
EDELLDELLDSPPASPSGSYITADGDSWTS------SPSCSLSLLAPAEGLDFPSDWGLS
PQGSVA--------------DEQEPNPTVPPESLSSESSLSADSSSSWDQE---GHFFDL
DFLANDPMIPAALLPFQGSLIFQVEAVEVTPLPPEEEEV-----------AANVPAPDGD
-LAGEGEEDSTSSSFLQSLSDLSIIEGMDEAFAFRDDTSAASSDS--DSASYAGADD-DR
LYSGEPHAQPSALAQKTEQEHRRG----------------------TAFWITN-----PQ
VS--EGEAH-LVHSQESTS-----EMEE-GLALSQESETTVTPHTLQ-------------
------------------------------------------------------------
--------------AALGLQMEAASRVPPQVGEEEADSTTGQAPATR-------------
------------------------------------------------------------
--------ALPQL--------------------------------------------SKE
VMSATLGQEPIIVEPQPVLQEAASPTLYTEPPEN----SKEEDGVLPSGLETVVAA----
--------------------------------TQGLQQ----------------------
----------------------------------------------------AEGGVILL
EDS---------------------------------------------------------
-------------------PEATELPPLQDADPTSGLEPLA------EATPGPQQAEESV
TI-SQDSSET------ELPPLQDAD-P----------TSGLELVATATP--G--------
------------------------------------------------------------
---------------------------------------PQQ-----------AEECVTI
SQDSSETE---------------------------------------------------L
PPLQDAG-----------------------------------------------------
------------------------------------------------------------
------------PTSGLEPVATATPGPQQAEE----SVTIPQDSPE--------------
--------------------------------------------TKFPPLQDAGPTSSLE
LEAAATPGPQQAEE--------------------------------NVT--IPQD-----
-----------------------------SP----------------------------E
TELPPGQDAD--------------------------------------------------
------------------------------------------------------PTSGLE
LMAGAKPE----PQQAEESVT----------------------IPQSSPERTLPPLQDAG
LTLAS-------------EPMAGD------------------------------------
------------------------------------------------------------
------------------------------------------------------THGAP-
--------GNKLM-ASVT------------QQE--LGLALELRPEPGEHDAGPDG-----
----------------DPEPSALNQTQKDGPEPT-------------AKTGTPWAPREEA
G---------------P-TLGMEAPGPPEPASGTGKEVAVDLS-APEGEICLEACVYVGD
GAKTHSPPKEALGAKNKRSVGPKPPAQEGG-P-----ASVPQG-----------------
--VRE-----APKACPTACPEVTQAQILRRGLSSK-----ATLEPRLPLAGAKEARLSSG
PKFPAK----AASSLDRDFP-KELTPSVS-PSQWL-------------------------
------------------------------------------------------------
-----------------------------------------------EPSLGLGNGKQPQ
RTPGMLKSSPLQLPENPARGRPRTPQNRLSD----PD--PSDPGVLAEEAPLALGPPNSR
LCQNPQEDSVESEEPPASRGLHVSRAVAQGAT-AAAAASGNTQPLGTGQQISLSRHHPLL
IPKAAPT---DAKDLASQISPPSQVPPPSGTQSLSS------------------------
-----------------PQGLPALEQQEDEDSLEEGKGESRGP--SWGD-----------
------------------------------------------------ILTPLFPSPDSP
RALGSGQHSD--S-HGESSVELDEQDISAPQ--MVQCPSQA----PTGSSEETIAKAKQS
RSEKKARKAMSKLGLRQ--IQGVT----RITIQKSKNILFVIAKPDVFKSPASDTYVVFG
EAKIEDLSQQVHKAAAEKFKVPSESSALVPESAPGSRVRPECEEEE--EE-ED---EEEA
GLELRDIELVMAQANVSRAKAVRALRDNHSDIVNAIMELTM-------------------
----------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------PQRPRGCS-----------------------
-----------------------------------------------------CHLHCPV
SCVGSCNESE--S-NDESIPELEEPEG-AEPRPMQTQAPLT---HSLGTGEESISKAKQS
RSEKKARKAMSKLGLRQ--IHGVT----RITIRKSKNILFVITKPDVFKSPASDIYIVFG
EAKIEDLSQQVHKAAAEKFKVPMEHSPLITETAPALTIKEE---S------EEEEEVDET
GLEVRDIELVMAQANVSRPKAVRALRHNNNDIVNAIMVSFACLTLN-DMTYFGAL-----
----------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
--------------MPGEAARAELLLPEADRPGPRTDLSCDAAAATTILGGDR------R
EPCALT-PGPSHLALTFLPSKPGARPQPEGASWDAGPGGAPSAWADPGEGGPSPMLLPEG
LSSQALSTEAPLPATLEPRIVMGEETCQA-LLSP---------------RAARTALRDRE
G-GHASPDPPPELCSQGDLSVPSPPPDPDSFFTPPSTPTKTTYALLPGCGPHGDAR--DS
EAELRDELLDSPPASPSGSYITADGDSWAS------SPSCSLSLLAPAEGLDFPSGWGLS
PRGSMV--------------DERELHPAGTPEPPSSESSLSADSSSSWGQE---GHFFDL
DFLANDPMIPAALLPFQGSLIFQVEAVEVTPLSPEEEEEE----------AVADPDPGGD
-LAGEGEEDSTSASFLQSLSDLSITEGMDEAFAFRDDTSAASSDS--DSASYAEADD-ER
LYSGEPHAQAT-LLQDSVQKTEEESRGGAKGLQAQEG---------TVSWALE-----AA
PQTSDRGAY-LSQRQELIS-----EVTEEGLALGQESTATVTPHTLQ-------------
------------------------------------------------------------
--------------VAPGLQVEVATRVTPQAGEEEADSTAGQESAAMAM-----PQPSQE
GISEILGQESVTA--EKLPTPQE--------------------ETSLILCPDSPQNLKEE
GG-------------------------------------LDLPSGGKP-VAAAMIVPRQA
EEDLTLPQDSA-MTPPLPLQDTDLSSAPKPVAAATLVS----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------QEAEEGLTLPQDSATTPPLPLQDTDLSSAPKPVA------AATLVPQQAEEGL
TL-PQDSAMT------PPLPLQDTD-L----------SSAPKPVAAATL--VSQE-AEE-
------------GLTLPQDSATTPPLP---------------------------------
-----------------------------------------------------------L
QDTDL-S-------------SAPKPV-------------------------AA---ATLV
SQQAEEGL----------------------------------TLP---------------
---------------------------------------------------------QDS
ATTPPLPLQDTDLSSAPKPVAAATLVPQQAEE----GLTLPQDSAM--------------
--------------------------------------------TPPLPLQDTDLSSAPK
PVAAATLVPQEAEEGLT-------------------------------------------
---------------------------------------LPQ--------------DSAT
TPPLPLQDTDLSSAPKPVA-----------------------------------AATL--
--V---------------------------------------------------------
------------PQQAEEGLT----------LP------------QDSAMTPPLPLQDTD
LSSAP-------------KPVAAATLVPQ-------------------------------
-----------------------------------------------------Q------
----AEEGLTLPQDSAMTAPLPLQDTGPTSGP-------EPLAVATP-QTLQAEAGWAP-
--------GTEPVATMAQ-------------QE--VGAALGPRPAPEEKNAALPT-----
----------------VPEPAALDQVQQDDPQPA-------------TEAGTPWAAQEDA
DS----------------TLGMEALSLPEPASGAGEEIAEALS-RPGREACLEARAHTGD
GAKPDSPQKETLEVENQQEGGLKPLAQEHG-P-----RSALGG-----------------
--AGE-----VPEAPPAACPEVSQARLLSPAREERGLSGKSTPEPTLPSAVATEASLDSC
PESSVG----AVSRLDRGCP-DAPAPTSAPTSQQPE------------------------
------------------------------------------------------------
------------------------------------------------PVLGLGSVEQPH
KVPSVLGTPLLQPPENLAKGQPSTPADRLLG----PD--PSAPGTLAEAALPPLEPPAPC
LCQDPQEDSVEDEEPPGSLGLPPPQAGAQPAA---AAVSGTTQPLGAGPRVSLSPHSPLL
SPKVASM---DAKDLALQILPPCQVPPPSGPQSPAG------------------------
-----------------PQGLSAPEQQEDEDSLEE-------------------------
---------------------------------------------------------DSP
RALGSGQHSD--S-HGESSAELDEQDILAPQ--TVQCPAQA----PAGGSEETIAKAKQS
RSEKKARKAMSKLGLRQ--IQGVT----RITIQKSKNILFVIAKPDVFKSPASDTYVVFG
EAKIEDLSQQVHKAAAEKFKVPSEPSALVPESAPRPRVRLECKEEE--E--EEEEEVDEA
GLELRDIELVMAQANVSRAKAVRALRDNHSDIVNAIMLTASATCTLPGLKAPAQAKNL--
---------WPPLIL-----Y-------------------------

------------------------------------------------------------
------------------------------------------------------------
--------------LPGRCIQGHLMIF-----SISTDLSCDAAAATTILGGDR------R
DPCALT-PGPSHLALTFLPSKPGARPQPEGASWDAGPGGAPSAWADPGEGGPSPMLLPEG
LSSQALSTEAPLPATLEPRIVMGEETCQA-LLSP---------------RAARTALRDRE
G-GHTSPDPPPELCSQGDLSVPSPPPDPDSFFTPPSTPTKTTYALLPGCGPHGDAR--DS
EAELRDELLDSPPASPSGSYITADGDSWAS------SPSCSLSLLAPAEGLDFPSGWGLS
PRGSMV--------------DERELHPAGTPEPPSSESSLSADSSSSWGQE---GHFFDL
DFLANDPMIPAALLPFQGSLIFQVEAVEVTPLSPEEEEEE----------AVADPDAGGD
-LAGEGE-DSTSASFLQSLSDLSITEGMDEAFAFRDDTSAASSDS--DSASYAEADD-ER
LYSGEPHAQAT-LLQDSVQKTEEESGGGAKGLQAQEG---------TVSWALE-----AA
PQTSDRGAY-LSQRQESIS-----EVTEEGLALGQESTATVTPHTLQ-------------
------------------------------------------------------------
--------------VAPGLQVEAATRVTPQAGEEEADSTAGQESAAMAM-----PQPSQE
GISEILGQESVTA--EKLPTPQE--------------------ETSLTLCPDSPQNLKEE
-G-------------------------------------LDLPSGGKP-VAAATIVPRQA
EEDLTLPQDSA-MTLPLPLQDTDLSSAPKPVAAATLVP----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------QQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVA------VATLVPQQAEEGL
TL-PQDSAMT------PPLPLQDTD-L----------SSAPKPVAAATL--VPQQ-----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---AEEGL----------------------------------TLP---------------
---------------------------------------------------------QDS
AMTPPLPLQDTDLSSAPKPVAVATLVPQQAEE----GLTLPQDSAM--------------
--------------------------------------------TPPLPLQDTDLSSAPK
PVAAATLVPQQAEEGLT-------------------------------------------
---------------------------------------LPQ--------------DSAM
TPPLPLQDTDLSSAPKPLA-----------------------------------AATL--
--V---------------------------------------------------------
------------PQQAEEGLT----------LP------------QDSAMTPPLPLQDTD
LSSAP-------------KPVAAATLVPQ-------------------------------
-----------------------------------------------------Q------
----AEEGLTLPQDSAMTAPLPLQDTGPTSGP-------EPLAVATP-QSWQAEAGCAP-
--------GTEPVATMAQ-------------QE--VGAALGPRPAPEEKNAALPT-----
----------------VPEPAALDQVQQDDPQPA-------------AEAGTPWAAQEDA
DS----------------TLGMEALSLPEPASGAGEEIAEALS-RPGREACLEVRAHTGD
GAKPDSPQKETLEVENQQEGGLKPLAQEHG-P-----RSALGG-----------------
--AGE-----VPEAPPAACPEVSQARLLSPAREERGLSGKSTPEPTLPSAVATEASLDSC
PESSVG----AVARLDRGCP-DAPAPTSAPTSQQPE------------------------
------------------------------------------------------------
------------------------------------------------PVLGLGSVEQPH
EVLSVLGTPLLQPPVNLAKGQPSTPTDRPLG----PD--PSAPGTLAGAALPPLEPPAPC
LCQDPQEDSVEDEEPPGSLGLPPPQAGAQPAA---AAVSGTTQPLGTGPRVSLSPHSPLL
SPKVASM---DAKDLALQILPPCQVPPPSGPQSPAG------------------------
-----------------PQGLSAPEQQEDEDSLEE-------------------------
---------------------------------------------------------DSP
RALGSGQHSD--S-HGESSAELDEQDILAPQ--TVQCPAQA----SAGGSEETIAKAKQS
RSEKKARKAMSKLGLRQ--IQGVT----RITIQKSKNILFVIAKPDVFKSPASDTYVVFG
EAKIEDLSQQVHKAAAEKFKMPSEPSALVPESAPRPRVRLECKEEE--E---EEEEVDEA
GLELRDIELVMAQANVSRAKAVRALRDNHSDIVNAIMVSEHWPLSLPLSC-PQGPRGVLM
LAPLRG--ASPNMTI----SFCRN----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------MSSLLIHVEDIAGQKVLRNFQNIQKSKNILFVISKPDVFKSPALNICFIFG
EAKMEDLSQQVHKAAAEKFKVPVELSPIITETVPDLRAKEES---------DEEEEVDET
GLEVRDFELVMAQANVSRAKAVRALRHNNNDIVNAIMELTM-------------------
----------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
--------------MPGEAARAELLLPEADGPGPRTDLSCDAAAATTILGGDR------R
EPCALT-PGPSHLALTFLPSKPGARPQPEGASWDAGPGGAPSAWANPGEGGPSPMLLPEG
LSSQALSTEAPLPATLEPRIVMGEETCQA-LLSP---------------RAARTALRDRE
G-GHASPDPPPELCSQGDLSVPSPPPDPDSFFTPPSTPTKTTYALLPGCGPLGDAG--DS
EAELWDELLDSPPPSPSGSYITADGDSWAS------SPSCSLSLLAPAEGLDFPSGWGLS
PQGSMA--------------DERELHPAGTPEPPSSESSLSADSSSSWGQE---SHFFDL
DFLANDPMIPAALLPFQGSLIFQVEAVEVTPLSPEEE-EE----------AVADPDPGGD
-LAGEGEEDSTSASFLQSLSDLSITEGMDEAFAFRDDTSAASSDS--DSASYAEADD-ER
LYSGEPHAQAT-LLQDSVQKTEEESGGGAKGLQVQEG---------TMSWALE-----AA
PQTSDRGAH-LSQRQESIS-----EVTEEGLALGQESTATVTPHTLQ-------------
------------------------------------------------------------
--------------VAPGLQVEAATRVTPQAGEEKADSTTGQASAAMAM-----PQPSQE
GISEILGQESVTA--EKLPTPQE--------------------ETSLTLCPDSPQNLKEE
GG-------------------------------------LDLPSGPKP-VAAASLMPQQA
EEDLTLPQDPA-VTPPLPLQDMDLSSAPKPVAAATTVP----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------RKAEEDLTLPQSPAVTPPLPLQDTDLSSAPKPVG------AASLVPQQAEEDP
TL-PQDPTII------PPLPLQDTD-L----------SSAPKPVAAATT--VPRQ-AEE-
------------DLTLPQDPTIIPPLP---------------------------------
-----------------------------------------------------------L
QDTDL-S-------------SAPKPV-------------------------AA---AT--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------I--
--V---------------------------------------------------------
------------PRQAEEDLT----------LP------------QDPTIIPPLPLQDTD
LSSAP-------------KPVAAATTVPR-------------------------------
-----------------------------------------------------Q------
----AEEDPTLPQDSAMTPPLALQDTGPTSGP-------EPLAVATP-QTLQAEAGCTP-
--------GTEPVATMAQ-------------QE--VV-----------------------
----------------------------PEPAPA-------------AEAGTPWAAQEDA
DS----------------TLGMEALCLPEPASGAGEEVAEALS-RPGWEACLEALVHTSD
GAKPDSPQKETLEVENQQGGGLKPQAQEHG-P-----GSTLGG-----------------
--AGE-----VPETPPAACPEVSQAWLLSPAREGRGLSGKSTLEPTLPSAVATEASLDSC
PESSVG----AVSRLDRGCP-DAPAPTSAPTSQQPE------------------------
------------------------------------------------------------
-----------------------------------------------PPVLGLGSVERPH
KAPSVLGPLLLQPPENLGKGLPSAPPDRPLG----PD--LSAPGTLAGAALPPLEPPAPC
LCQDLQKDSVEEEEPPGSLGLPTPQAGAQPAA---AAVSGTTQPLGTGPRVSLLPHSPLL
-------------NLALQISPPCQVPPPSGPQSPAG------------------------
-----------------PQGLSAPEQQEDEDSLEEGKGEGRIE--VPWGLGQLDSSLELS
WAGGPLRWWGGGPRPHSHHGELALLPLALMWQQGQGPESPSPPPRSKRPSSHLSPSPDSP
RALGSGQHSD--S-HGESSAELDEQDILAPQ--TAQCPAQA----PAGSSEETIAKAKQS
RSEKKARKAMSKLGLRQ--IQGVT----RITIQKSKNILFVIAKPDVFKSPASDTYVVFG
EAKIEDLSQQVHKAAAEKFKVPSEPSALVPESAPRPRVRLECKEEE--E--EEEEEVDEA
GLELRDIELVMAQANVSRAKAVRALRDNHSDIVNAIMVSTG-----PFPCPRAVPKGLEG
S---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------EGRATPEPRLPGAVASEAWLGSC
AEPPLR----AVPRLGEGYP-KEPAPTSPPPSWQP-------------------------
------------------------------------------------------------
-----------------------------------------------EPVLSLGSSQRAQ
AAPRIPGPFPPQSLESPTGGLPRAPQDSILG----SE--PSAAGVLVEAAPPPMALPGPC
PCQGPREDSMEGEEPPGSPSLPSPKAGAQRAV---AAFSGTTNLPGAGQRVTLPPHAPLL
SPKAASKRGSHAKDLASQLSPPCQVPPGSGPWSPAG------------------------
-----------------PRGLPATEHQDDQDSLEED------------------------
----------------------------------------------------------SP
RAPGSGQHSD--S-HGESSAELEE-NFSGPQ--SAQCPAAA----AGSGSEETVAKAKQS
RSEKKARKAMSKLGLRQ--IQGVT----RITIQKSKNILFVIAKPDVFKSPASDTYVVFG
EAKIEDLSQQVHRAAAEKFKVPAEPSALVPESAPGPHVRPC-EEEE--G--DEEEEVDEA
GLELRDI-----------------------------------------------------
----------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
--------------MPGEAARAELLLPEAGGPGPRTDLSCDAAAAT-TPKGDR------L
EHCALS-PGPSTLALTFLPSKPGTRPPPEGASWDAGPGRAPSAWAVQTEGGPSPG-----
-SPEVRPAEGPLPASLEPRIVMGEETCRRAPPLP---------------RAALPELRDWE
G-GHASPHPPPELRSQGDPPVPFPAPDSDSFFTPPSTPTETACPLLPGPGPRRDAG--DA
QAE----LGDSPPASPSGSYVTADGDSWAS------SPSCSLSLQAPAEGLDVPSGWGFS
PAGSVA--------------DERELPPAQTSDTPSPESSLSGDSSSSWDQE---GHFFDL
DFLANDPMIPASLLPFQGSLIFQVEAVEVTPLPPEEE------------GEQEAPVPRGD
-LAGEGEDDSTFASSLHSLSDLSITEGMDEAFAFRDDTSAASSEP--DSASYAGADD-ER
LYSGEPHAQPTTLLQD----SPAD----------------------AAFWGPE-----PA
LGAAPREAGTAAKSQEPGS-----EIPEVGPTSGQASAAGVGPHIPQEAP--GLTGVTPQ
AQVEEAGSTMGPAPVAMVALGPLKEGDSPALGTEPRTSKGEEGLASLQNRKEETGQGSAA
AASPERQPEVDLVAPLPLQ-----DAGLPSDQE---------------------------
------------------------------------------------------------
----------------SATEASPERQPEVDLVAPLPLQDADIPLVQES-ATEASPEPQPE
ER---------DLMAPLPLQDAGLPSDQESATEASPEPQPEEVDLV-APLPLQDAGLPSD
QESATEASPEP------------QPEERDLVAPLPLQDADIPLVQGFASE----------
-TSPEPQL---EEDLMASLPLEDADLPLPQPGV---------------------------
------------------------------------------------------------
--------------------HLMAPLPLQDAGLPSGQESAT------EASPE--------
---PQPGELT------AAPPLQDAD-F----------PSG--------------------
------------------------------------------------------------
-----------------------------QGSASETSPEPQPEED-LMASLPLEDANLPL
VQGSA-------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------TE
ASPEPQPEV---------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------HL
MAPLPLQDV---------------------------------------------------
-----------------------VLPSGQESATE--------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------TKEVDLTVFLPLQDADLTSDQESTT------------KALQTDAGCTP-
--------GTGPMATTA-------------QRK--RSKTSGLRPEPEEKDPDHSG-----
----------------GADALALDQAHPSGSEPA-------------ADARTPWALQ---
G-----------------DPTTEAPDLP-EPDSSGEET---AR-APEQGACLDGHVRGDD
EAEPSLSPKEALGAEKQGGKVL---------------EPVAL------------------
----------SPEASPAACLEAGPVRPPSPVEEGR-----ATLGPRLPRAAASEAGLGPG
SESPSR----AVPRLGGGCP-KDPAPTLPLPSRQP-------------------------
------------------------------------------------------------
-----------------------------------------------EPMLGRGSGGQAR
AALRVLSPSPPQPPESRARHLASAPQDRTRS----PE--PPAPGVPMESAPTPSGPPAPC
SCQGPREDLGEGQEPLGSPGLPPPRARARRAA--A-AFSGTPNPPGAGQ-VGLPPQPLPL
SPKAAPKGGNHAKDLASSISPPCQVPLGSGPRSPAG------------------------
-----------------PRGLPATEQQDDQDSVEED------------------------
---------------------------------------------------------SP-
RAPGSGQHSD--S-HGESSAELEEQDLSGPQ--TAQCLAQA---PAGGASEETVAKAKQS
RSEKKARKAMSKLGLRQ--IQGVT----RITIQKSKNILFVIAKPDVFKSPASDTYVVFG
EAKIEDLSQQVHRAAAEKFKVPSEPSPLVPESAPGPRVRPECEEEE--E--EEEEEVDEA
GLELRDIELVMAQANVSRAKAVRALRDNQSDIVNAIMLTLKQGDTLGHLSSK----CA--
RGPSMGRGKGADRAVTTGDQRCHHGCDMEGGCQKLEKAGDGFSLET

------------------------------SALPP-------------------------
------------ALRSAWRGSARSLGLIG--------G---RGSRGAVAELATPSALTDR
GTERQGDRQARVQAMPGEAARAELPLPEAGGPGSRTDLSCDAAIAT-ILKGDQ------R
EPHALT-PGPSPLALTFLSSKPGARPQPEGASWDAGSGGAASTWADPAEGGPSPGVLPEG
LPLQPLPAEVPLPTTLEPRIVMGEETCQV-IPSP---------------RAAWPVLRDRA
G-GHIALHPPPELCSQGDSPVPSPPPDLDSYFTPPSTPTKTTYALLPDQGPHGDAW--DL
EAELLDELLDSTPASPSGSYITADGGSWAS------SPSCSLSLLAPAEGLDFPSDWGLS
PSGSVV--------------DELEPHPTGPPEPPSSESSLSTDSSSSWSQE---GHFFDP
AFLANDPMIPAALLPFRGSLIFQVEAVEVTPLPQEEEAEEEEEEEE---VAAGAATPDGD
-LAGEGEDNSTSASFLQSLSDLSIIEGMDEAFAFRDDTSAASSDS--DSASYAGADD-DR
RYSGEPHAQPSAPDTEQEPR---------------SR---------AAFQGTE-----FT
PRISEQE-SRLSNSQESIA-----EIVEEALALDIETEATVTPPNR--------------
------------------------------------------------------------
-------------RAAPGSQVEEATTVTPRVGKEEVDSVAQQAPRARP-------QPCQK
GRSTTSGCKPA----------------------TAESILDLQEEARPTLCPVLPCNLKEG
G--------------------------------------QGLPATLEY-VAVASVRPQEA
EEGVTIPQDSPKPLPPFLHYADPS-SDPESVAVV--------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---SLGLQRDEECVIALQDVPGASPPPLQSTDPTSGPESRA------MATFEFQHAKKGI
TE-PQDSPVT------SSSPLQGSD-P----------TLDPEPEAVVTL--GAQQ-DEG-
------------IVPVPQDSP---------------------------------------
------------------------------------------------------MACL--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------ALQGSDPTLDPQPVLAATSGPQQAEE----GVTKPQVAPVASH-----------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---SPLQSLGSTSDLQPVAAATPGS-----------------------------------
------------------------------------------------------------
-------------QQ---------------------AEGLSARAPQDTPVTAPPSLPDTD
CTSDP-------------------------------------------------------
------------------------------------------------------------
---------------------------------------ELIVQDTS-QTLQRETDYAP-
--------ETNPPASGV-------------HQE--LGVALGPKPVPEQDAEPSP------
----------------DWAPAASNKAQQNGSEPAVKADSFGAPE----------------
--------------ESRPTLSTK---ISEPTSCMGEKGAESIS-ALKQR----ACLEARE
GVKTHSPQREAPGGKNKQGRGPKRPGQGNG-S-----KSASQG-----------------
--AGE-----TSKTLSAACSEVSQKQLSS-----------DTLGPGLPVALSVQARLGSC
SGSPAR----TTCTLSRVHS-EETSRSA--------------------------------
------------------------------------------------------------
-----------------------------------------AAFQHLEPVLGLGNRDQPQ
MTPGALNPSPA----RSASGLPTTPQNRFLD----PD--PPAPSALDRASQTSPGPPAPC
LCPTPQKVSAEEEEPPSSRGLMP-RAGAQGMA--AISSSGSTKPLGARHRVSLSPHST-L
NPKATPT---DAKDLACIISSPCQVPPPSGTQNPSG------------------------
-----------------PRGFLAGEQEEDEDSLEEDTRGW-----DWRA-----------
-------------------------------------------LCNSKRPSHLTPSPDSQ
RAPGSGQHSD--S-HGESSAELDEQDTP-PQ--KVQCTAQG----PAGSNEETIAKAKQS
RSEKKARKAMSKLGLRQ--IQGVT----RITIQKSKNILFVIAKPDVFKSPASDTYVVFG
EAKIEDLSQQVHKAAAEKFKVPSESSALVPELAPGPRVRPECEEQE--E---EDEEVEEA
GLELRDIELVMAQANVSRAKAVRALRDNHSDIVNAIMELTM-------------------
----------------------------------------------

------------------------------------------------------------
-------AVAAHAHS-----AAGGRG---RDVTTPPPL--AEGRRP----------RTDG
AEGQGTEDRDGAQAMPGEAARAELPLPEADGTEPHTDLTCDVPAAT-ILGGEQ------R
DPHALT-PGPSPLALAFLPSKPGTRPQPEGASWDAGPGGGPSAWADPAEGSLN--LLPEG
LHPQA------LPATLEPRIVMGEETCQA-PPSP---------------RAVLPALREQ-
-----------ELCSQDDPPVPSWSPDPEPYFTPPSTPTKATCTLLLSPGLHRDTW--DP
EAEL----LDSLASSPSGSYVTADGDSGTL------SPSCSLSLLAPTEGLDFPSGWSLS
QPESVA--------------EEWEPPPAET---PSSESSLSGDSGSSWGQE---GHFFDL
DFLANDPMIPAALLPFQGSLIFQVESVEVTPLPAEEEEEE---------VAADTPAPAGE
-AAGED-EDSTSASFLQSLSDLSITEGMDEAFAFRDDTSAASSDS--DSASYAGADD-DR
LYSGEPHAQPSAEQEC------------------ADR---------AVFWAAE-----VP
E-----GEACLSQSQESIT-----GVMEEGLASSQEPAAAVTPHTGQATP--GLTPQVDS
VAGRAPATWA--------PAHPTQDKKGTAVGQPPDCTE---------------------
--------------AKPAL-----------------------------------------
-----------------------------------------QEAIGSTMCPESPEPRGHQ
-------------------------------------EAPGLPGGLES-VAVATLRLLQA
EGDNPLPQESPKSALPSLLDEDSISD-LEFVAAAMLGSQKAEGNL------------PLP
QDSS-ES------------------------AL-------LPLVD---------------
---EDPIS---EQELVAAAT---------------------------LRPLQAEGGNPLP
QDSPKSAFPSPLD--EDP------TLGIECVTA---------------------------
--ATLESQEAEGGILLLQDSPESSPPTLQDEDPTPDPKSMA------AVTLGPLQAGGGT
LL-PQDSPKSS-----SPLSLQDAD-P----------IPGPEFMAAVTP--GSLQ-TEG-
------------GTPLPQ------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------DS------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------PE
SALLPLLDKDSISDLEAVAAATLRPLQAEG------------------------------
---------------------------------------------------------GVP
LPQDP-------PES------------ALPPLV---------PLPQDSPESSPPSLQDED
PTP---------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------GPKPMAAVLG----------PLQSG--GGVLLP-QNSPET------------
------------------ELLP-------------------------------LLDE---
-----------------------------DLASRQEPMAMVMLGSLQAEGEKEA------
--------QVPTGDGNQRARGPKAPTQGQG-P-----RSAPRG-----------------
--ARG-----APKTLCATYPEASQVQPQSPSREGRALGGKGTPASRLPTALVAEAQQGSC
LGSPAR----AMSSPKK------PGPSAPSSPQQE-------------------------
------------------------------------------------------------
------------------------------------------------P--VPGSGQRPL
ATPSLLSPSPPSHPRTPNRGPPSEPRSRLLD----PN--PSAPGA-------------SR
PHRGPRDDSMEGVEPLASRGPPQPRVGAQRP--------------------------PLL
SPKAAPA---DAKEPASRTSPPCQVPPPSGSRGSRR------------------------
-----------------PQGPPASEQQADEDSLEEAPQGPH-------------------
------------------------------------------------------------
----SRKHRAGMS-TGRPSPVLMKS------------------QPEGD-------FRGRS
PDPGPLSQAMSKLGLRQ--IQGVT----RITIQKSKNILFVIAKPDVFKSPASDTYVVFG
EAKIEDLSQQVHKAAAEKFKVPSESLALVPESAPGPQLRPECEEEE--E---EEEEVDES
GLELRDIELVMAQANVSRAKAVRALRDNHSDIVNAIMELTM-------------------
----------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
--------------MPGEAAGAELPLPEAGGSGSRTDLPCDAAIAT-ILKGDQ------R
EPHGLT-PGPSPLALTFLSSKPGARPQPEGASWDAGPSGAASTWVDPAEGSPSLVVLPEG
LPLRPVPADVPLPTTLEPRIVMGEETCQV-LPSP---------------RAAWPVLRDRE
G-GHTALHPPPELCSQGDPPVPSPPPDLDSYFTPPSTPTKTTYALLPDHGPHRGAW--GL
EAELLDELLDSTPASPSGSYITADGDSWAS------SPSCSLSLLAPAEGLDFPSEWGLS
PSGSVV--------------DELEPHPTAPPEPPSSESSLSADCSSSWSQE---GHFFDP
NCLANDPMIPAALLPFRGSLIFQVEAVEVTPLPQEEEEDEEEGAA---AAAAAAATPDGD
-LAGEGEDDSTSASFLQSLSDLSIIEGMDEAFAFRDDTSAASSDS--DSASYAGADD-DR
LYSGEPHAQPSAQNIEQEYRSRTA------------------------FPGA----AEFT
PQTSEQ-EICLTDSQESAA-----EIAEEILTLGIESEATRTPPDRQ-------------
------------------------------------------------------------
--------------TAPDPQVEEATTVTPWVENKDDSVA--------EQASKALPEPCQK
GTSMILGCKPLTA----------------------KAIPDLQEGAGPAMCPVLPENLKEG
G--------------------------------------QGLPSTMEY-VAVASVGPWKA
EGGVAIPQDPFMTLPPLLQ-NTDPTSGPE-------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------SV
AVVMLEPQQDEGCVTVLQDVPVVSLPSPQSTDPTPGPEAGA------MATFEFQQAKEGV
PE-LQDTPVA------SSPALQASD-P----------TSEPEPEAVLTL--RSQQ-DEE-
------------IVT---------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------------VPQES
PTASSVPLQSSDPTSEPEPEAAATPEPQQPEE----GVTIPQVAPVALPS--PLQGLDST
SD----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------LESVVAGTMESWQDEGI-----------------------------
------------------------------------------------------------
-----------------------------------------ATATQDMPVVAPPPLGGIE
------------------------------------------------------------
------------------------------------------------------------
---------------------------S-------TSDPELSAQDTP-QALQREAGYTP-
--------GTKPSVSEAH-------------QE--LGVALGPRPVPKEQDAKP-P-----
----------------HSELPASDQAQQNGSEPVVKNDNLGVPGEGS-------------
----------------GPTLST---KTSEPLSCMGEKVTENLA-APKPGACL----EAHD
GAKTHSPQRQASRAKNKCGRGPKPPGQGKGSK-----STASQG-----------------
--TTE-----TFKAHSAARSETSQPQLMNSAGEGTSLSVKDSSGPRLPVAVSVQSKLGSC
PGSPAR----ATCTLSRVYS-EETAR----------------------------------
------------------------------------------------------------
---------------------------------------CAPPFQHPEPVLGLGSGEQPK
VTLGTLNLSS----ENSAGDLLTTPQNRLLD----PDPDPSAPSALNRAFQSSPGPPDPC
LCPTSQKDPVEEEKPSASHGLR-SRAGVQGAA--AITTSGSTKPLGARQRVSLSPHS--A
NPKVTPT---DAKDPACIISSPCQVPPPSGTQNPSG------------------------
-----------------PRGFPAHEQ-EDEDSLEEDSQRAPGSGQ---------------
------------------------------------------------------------
-------HSE--S-HGESSGELDEQDIS-PQ--KSQCPAQD----PAGSNEETTAKAKQS
RSEKKARKAMSKLGLRQ--IQGVT----RITIQKSKNILFVIAKPDVFKSPASDTYVVFG
EAKIEDLSQQVHKAAAEKFKVPSESSALVPELAPGPRVRPECEEQE--E---EEEEVEEA
GLEPRDIELVMAQANVSRAKAVRALKDNHSDIVNAIMELTM-------------------
----------------------------------------------

------------------------------------------------------------
------MSALPLALR---------------------------SAQGAVAVQATPSALTDR
GTERQGYRQAHVQAMPGEAAGAELPLPEAGGPESRTGHSCDAAIAT-ILKGDQ------L
EPHGLT-PGPSPLALTLLSSKPGARPQPEGASWDAGPSGAASAWVDPAEGSSSLVVLPEG
LPLRPVPAEGPLPTTLEPRIVMGEETCQV-IASP---------------RAAWPVLRDRE
G-GHPALHPPPELCSQGDPPVPSPPPDLESYFTPPSTPTKSTHALLPDHGPHRDAW--DL
EAELLDELLDSTPASPSGSYITADGDSWAS------SPSCSLSLLDPAEGLDFPSDWGLS
PSGSVA--------------DDLEPHPAAPPEPPSSESSLSADSSSSWSQE---GHFFDP
NFLANDPMIPAALLPFRGSLIFQVEAVEVTPLPQEEEEDEEEVAAPAAAAAPAAATPDGD
-LAGEGEDDSTSASFLQSLSDLSIIEGMDEAFAFRDDTSAASSDS--DSASYAGADD-DR
LYSGEPHAQPSAQNTEQAYRSRAT------------------------FPGI-----EST
PQTSEQ-EIHLINSQESVA-----EIAEEILTLGLESEAMRTPPDQQ-------------
------------------------------------------------------------
--------------AAPGPQVEEAPTVTPWVGNKVDSVA--------EQASKALPEPCQE
GRSTILGCKPLSA----------------------EAIPALQEGASPSLCPVLPEK-KEE
G--------------------------------------QGLPSTLEY-VAVALEGPWKA
EGGVTIPQDPLMTLPPLLQ-STVPTSGPE-------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------SV
VV-VVEPQQNEGCVTVLPD---VLPPPRQSADPTSGPEAMA------VATYEFQQAKEGI
PE-LQDSPVA------SPPALQGSD-P----------TSEPEPEVVVTS--RSQQ-DEG-
------------IVI---------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------------VPQES
PTASSLTLQSSHPTSDQECEVAATLGPQQAEE----GVTIPQVAPVASPS--LLQGLEST
SD----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------LESVVVGTLESQQDEGT-----------------------------
------------------------------------------------------------
-----------------------------------------ATATQDTPVMAPPPLRGTD
------------------------------------------------------------
------------------------------------------------------------
---------------------------S-------TSDPELIAPDTS-QALQREAGYTP-
--------GTKPSVSEAH-------------QE--LGVASGPRPVPKEGDAEPPP-----
----------------HSAPPASNQAQQNGSEPGDKSDSFGAPEEES-------------
----------------GPTLST---KTSEPTSCLGEKVAANMS-APKRGACL----EAHD
GVKTHSPQREALRSKNKRGRGTKSPGQGNGPK-----SATSQG-----------------
--AME-----TFRAHSAAHSEVSQPQLIS---------NKDTSGPRLPVAVSVQARLGSC
PGSPSR----ATCTLSRVYA-EETAR----------------------------------
------------------------------------------------------------
---------------------------------------CAPPFQHSEPMLGLGSAEQPK
VTAGIPNLSP----DNSAEQ-VTTPQNRFLD----PDPAP---STLDRASQSSPGPPDPC
LCPPPQKASVEEEKPPASCNPM-PRAGAQGAA--AITTSGSTKPPGARQRVSLSPHST-L
NPKVTPT---DTKDLACIISSPCQVPPPSGTQNPSG------------------------
-----------------PRGFPALEQ-KDEDSLEEDVQRAPGSGQRWESH----------
------------------------------------------GESSSELDEYLAPPQDAQ
RAPGSGQRSE--S-HGESSSELGEQDLS-PQ--KSQCPAQG----PAGSNEETIAKAKQS
RSEKKARKAMSKLGLRQ--IQGVT----RITIQKSKNILFVIAKPDVFKSPASDTYVVFG
EAKIEDLSQQVHKAAAEKFKVPSEPSALVPELSPGPRVRAECEEQE--E---EDEEVEEA
GLEPRDIELVMAQANVTRAKAVRALKDNHSDIVNAIMELTM-------------------
----------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------PGARPQPEGASWDAGPGRASPAWALPAEGGPSPG-----
-LPEGRPVAPPLPATLEPRIVMGEETCRP-PSPP---------------STATPELRDWA
G-GHANLKLPSELCSQSDPPVPFPHSDPDSYFTPPSTPPQATCALPSGLRPCREVC--NS
EAG----LLDSPPTSPSGSYITADGDSWAS------SPSCSLDMLAPVEGLDSRSGRGLS
PLALTR--------------DSHSL-----LVPPSSASSLSADSSSSWSQE---EPLFDL
DCLANDPMIPAALLPFQGSLIFQVDAVEVTLLPPSEEVAT----------ETKTPSPSGD
-QDEESEDENPSASFLQSLSDISIIEGMDEVFAFRDDTSAASSDS--DSASYAGADD-ER
LYSGXXXXXXXXXXXXXXXXXXXX------------------------------------
-----XXXXXXXXXXXXXX-----XXXXXXXXXXXXXXXXXXXXXXXXXX---XXX----
----------------------------------XXXXXXXXXXXXXXX-----------
----------XXXXXXXXFHQEAVTTVTPHARLAEAGPGVSLEPA---------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------ATGPPQW
RGN---------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------SDTSTGQEDVA-------RVTPPLLTEDGF
II-GQ--VIVA-----TPVTLQEEE-H----------TLGPGTAATERP--QTPQEE---
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------EVSPTPCPDSLAGS--------------------------------
------------------------------------------------------------
VTTQNKEEAGSGLTSSQESVAPATPVPLSE------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------G--
-----------------------------------------CGLHQE-------------
------------------------------------------------------------
------------------------------------------------------------
-------------SVPMATLLPLQKEAA------LPLSQEPIAVAT-LQALQEEVGCPL-
--------GASTDATMAR-------------HD--VGVALGLVPASELTAVAKPL-----
------------ATEPEAELVALDQGQHDDLEPEAEAV-------------TLWASGRDA
G----------------------------------------LT-----------------
------------------------------------------------------------
----------------------------------------------------------S-
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------EP-----------
------------------------------------------------------------
-----MSDREEQQEATGAPLGPEPKVGRDYQH---------------------------L
DD--------GAKXXXXXXXXXXXXX---------X------------------------
-------------------XXXXXX-XXXXXXXXXX------------------------
----------------------------------------------------------X-
X---XXXXXX-----------------------------------XXXXXXXXXXXXXXX
XXXXXXXXAMSKLGLRQ--IPGVT----RITIQKSKNILFVISKPDVFKSPASDTYVVFG
EAKIEDLSQQVHKAAAEKFKVPPDPSAPASESAAGLRVTPECQEEE--E--EEEEEVDET
GLELRDIELVMAQANVSKAKAVQALRANHSDIVNAIMELTM-------------------
----------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
--------------VHGTTATM-----ERIRPEAAADLSCDAAAAT-ILREDG------Q
ESCALT-PGPSPLALKFLPSKPGARPQPEGASWDAGPGGTPSAWADPAEGGPSPALLPEG
LRPQARPPEAPLPATLEPRIVMGEETCQA-LPWP---------------RAARPVLRDQE
G-GHVSPSPPPELYSQGEPSVPSPPPDLDSYFTPPSSPPKTTYALAPGRGPPRDAW--DP
EVELLDELLDSPPASPSGSYITADGDSWAS------SPSCSLGLLAPAEGLDFPSGWGLS
PPGSVA--------------DEQELRPAGPLGAPSPESSFSADSSSSWGQE---GHFFDL
DFLANDPMIPAALLPFRGSLIFQVEAVEVTPRPPEEEEEEEE--------AASGSGPEGD
-LAGESEEDSTSASFLQSLSDLSITEGMDEAFAFRDDTSAASSDS--DSASYAGADD-ER
LYSGEPHAQPT-LLQDSVQKTEERAAGA-AGPQV-------------------------Q
VSEG-RGEAPLAQSPNSTA-----DIAEEGPASGQEPAATVTPPTVQ-------------
------------------------------------------------------------
--------------AAPGPRVEAATDMTPQAGEKEAGQA----PAAGA-----APPSSPG
GTLHVLGKE---------------------------------------------------
-----------------------------------------------P---------VAA
E-------------MPPTL-----------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------QEEASL
TL-HPDSPQN--------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----SKEEAGPHLPSGPKPVAAGTPVPQQAED----SLALPQDPAMTA------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------PLSL----
------------------------------------------------------------
------------------------------------------------------------
-----------------------QVTSPSPGR------EPVVAAAPSQALQTEEAGCAP-
--------GTEPVASTAQ-------------QE--VGVALGLRPAPEERDVVLPG-----
----------------APEPPALDQVQQDDQEPAVDAG-------------TPRASQE--
--------------DAGPTVGMEASDLPESASGSREEGAAEGLSVPKREACLEAQGHTGD
GTEPHSPAKEALGAENQRGGGLEPPAQGHG-P-----GSAPQG-----------------
--AGE-----IPQRQPASCPRAGRASPLSPAKEGGGPSSEVILGPRLPTTVAAEACPGSC
PGEPAP----P--------------------A----------------------------
------------------------------------------------------------
--------------------------------------------QWLDPVLSLGGAEQLQ
VAPRVLGPSLPLPPENPAPALPSTLQDKPLG----PD--SSTPGVLAGAAPLLQEFPGLC
LCQGPWEDPVRDKEPQGAPGLPLPQAGAQPAA----AISGTTQPPGAGQQVGLSPHSPLL
SPKAVPR---DAKDLALRISLPCQVPPHSGPRSPAG------------------------
-----------------PQGLPAPEQPEDEDSLEEGEDELGVGPHGWAGWTPPQVWHCWP
GLEACHSGRSR----------PHAPLWGPGTASSGPSRHPSPDSPWAPGPPHASPSPDSP
RAPGSGHHSD--S-HGESSAELDEQDSSAPQ--TAQSPA--FPQALTSGSEETIAKAKQS
RSEKKARKAMSKLGLRQ--IQGVT----RITIQKSKNILFVIAKPDVFKSPASDTYVVFG
EAKIEDLSQQVHKAAAEKFKVPSEPSVLVPESAPRPRARLECEEEE--E---EEEEVDEA
GLELRDIELVMAQANVSRAKAVRALRENHSDIVNAIMELTM-------------------
----------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-------------------------------------LSCDAAAATTILGGDR------R
EPCALT-PGPSHLALTFLPSKPGARPQPEGASWDAGPGGAPSAWADPGEGGPSPMLLPEG
LSSQALSTEAPLPATLEPRIVMGEETCQA-LLSP---------------RAARTALRDRE
G-GHASPDPPAELCSQGDLSVPSPPPDPDSFFTPPSTPTKTTYALLPGCGPLGDAG--DS
EAELWDELLDSPPPSPSGSYITADGDSWAS------SPSCSLSLLTPAEGLDFPSGWGLS
PQGSMA--------------DERELHPAGTPEPPSSESSLSADSSSSWGQE---GHFFDL
DFLANDPMIPAALLPFQGSLIFQVEAVEVTPLSPEEE-EE----------AVADPDPGGD
-LAGEGEEDSTSASFLQSLSDLSITEGMDEAFAFRDDTSAASSDS--DSASYAEADD-ER
LYSGEPHAQAT-LLQDSVQKTEEESRGGAKGLQVQEG---------TVSWALE-----AA
PQTSDRGAH-LSQRQESIS-----EVTEEGLALGQESTATVTPHTLQ-------------
------------------------------------------------------------
--------------VAPGLQVEVATRVTPQAGEEEADSTTGQASAAMAM-----PQPSQE
GISEILGQESVTA--EKLP--QE--------------------ETSLTLCPDSPQNLKEE
GG-------------------------------------LDLPSGPKP-VAAALLVPQQA
EEDLTLPQDPA-MTPPLPLQDTDLSSAPKPVGAASLVP----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------QQ---------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------KPVAAATIVPR-------------------------------
-----------------------------------------------------Q------
----AEEDLTLPQDSAMTPPLPLQDTGPTSGP-------EPLAVATP-QTLQAEAGCTP-
--------GTEPVATMAQ-------------QE--VGAALGPRPAPEEKNAALSR-----
----------------VPEPAALDQVQQDDPQPA-------------AEAGTPWPAQEDA
DS----------------TLGMEALCLPEPASGAGEEVAEALS-RPGWEACLEALVHTGD
GAKPDSPQKETLEAENQQGGGLKPLAQEHG-P-----GSALEG-----------------
--AGE-----VPEAPPAACPEVGQAWLLSPAREGRGLSGKSTLEPTLPSAVATEASPDSC
PESSVG----TVSRLDRGCP-DAPAPTSAPTSQQPE------------------------
------------------------------------------------------------
------------------------------------------------PVLGLGSVERPH
KAPSVFGPLLLQPPENLGEGLPSAPPDRPLG----PD--PSAPGTLAVAALPPLEPPAPC
LCQDLQEDSVEEEEPPGSLGLPPPQARAQPAA---AAVSGTTQPLGTGPRVSLLPHSLLL
SPKVASM---DAKDLALQISPPCQVPPPSGPQNPAG------------------------
-----------------PQGLSAPEQQEDEDSLEE-------------------------
---------------------------------------------------------DSP
RALGSGQHSD--S-HGESSAELDEQDILAPQ--TAQCPAQA----PAGSSEETIAKAKQS
RSEKKARKAMSKLGLRQ--IQGVT----RITIQKSKNILFVIAKPDVFKSPASDTYVVFG
EAKIEDLSQQVHKAAAEKFKVPSEPSALVPESAPRPRVRLECKEEE--E--EEEEEVDEA
GLELRDIELVMAQANVSRAKAVRALRDNHSDIVNAIMELTM-------------------
----------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
--------------SPGVRRGAPCLLPASNQAGPRAAEPHDAAAST--PSGDLSTPEDLP
MRGDLT-PGPAPIPLAFLPAKRGDRPQPEGASSDTGAGSTSSGRTALGECGPVVG-----
-PPKGLSEEPLILESLEPRVVMGEETSSS-GPRRAPPELPKEPQAAAPLTVTDSELRDLE
G-KWAGPSPPPELLSQGDLPVPSPRPDPDPYFTAPSTPTKLACSYLFSHSLCLSEEPSDA
E-----------------------AASWASSSSFSTSPSCSPNLLVETEGLDAPENGDFS
LLCPNEEGSQESPLGGASDSDDTELLPAGPRDLPSSESSLSGDSGSSWNLGQGGDPFPDM
GFPGGEPMIPATLLPFRGSLIFEADAVEIMALPQEEAPS---------------------
-PESDGEDDSTSASFLQSLSETSINEGVDEAFAFRDDTSATSSDSD--SASYAGEED-ER
LYSEEPHAQPPGLLWFGSSEAGD----GFPAKEKEEPASLLAQGPELSSGGEPA------
-------AMASTPGTPQGADLEPTAVSAT---------SWTPQEANLEPTAVSATPRIPQ
----EADLEPTVVSATHRT----P------------------------------------
---------------QEGTLEPTVVSVTPQT-----------------------------
----------------------------------------PQ-GADLEPTAVS-------
--------VTPGTPQGADLEPTAV--------S----------------------VT---
-------------------PGTPQGADLEPTAVSVTPRTPQGADLEPTVVSVTP------
---GTPQGAD--LEPTAVSVTPQIPQGADLELT--A--V--SV-TPWIPQGADLESTMAS
VTPGTPQGADLEPTAVSVTPWIPQGADLEPT-AV------------SATPGTPQR-----
------ADLEPTAVSATPGTPQRADLEPTVASV---------------------------
-------------T---------PHTPQGADLEPTEVSV-------------TPQTPQGA
DLEPTA--VS------VTPPIPQGADLEP---------TAVSA-----------------
-THQTPQEGTLEPTALSVT-------------------PQTPQEG-ADLEPISTETS---
-----------------------------Q-----TLQEAANLEP------ITMMTLQNL
QETTLQE-------------AVVLEPIATETSQ--TLQEAVVLETLQEAVVLEPIATETS
QTLQEAVVLEPIATETSQTLQEAVVLEPVAKNAPQHRQEEGDPEPVAKNT----------
-----PQTRQEEE--GLEPTATMLCQ----------------------------------
-----TTQE----AVSPDCIAGPVTPPALQATGAEPRVVTSQTSQEVSP-----EPTAAA
MPPHPP--------------------------------------------QEAGFPFGL-
----EM----------------SQVE-------S------PLLTVETLPA-------DPA
AGLGSRGGLVAG---------------PCAH----------------EGAEPLTPQREAL
PEAREPADS-----RGVEGQAGPA------------------------------------
------------------------------------------------------------
-------------------------ESEGP------AG----ENESSEHP--PASPTTTD
NVSGSPDALQASEETGAPEPN------------S--AASLEQ--------I-DVLGKELL
AEAAF------------N-----LEEKCPEG-LAP----------------------E--
------------------------------------------------------------
--------------------PSPRKRSPVPSEG--SGLKAD--LRQDTERAPLLRPKEEG
PSSSSP----------K---APSDFPFTPPPQG---------------------------
------------------------------------------------------------
-----------------------------------------------------------P
LVVAPLPLVDTD----PDCSPEEPEGPSGEKR--PLPRSP------LGR----E------
-KPPKLAAGPNHKAVSGNTPPLALCPSDLGTVAAR-------------------------
------------------------------------------------------------
------------------------------------------KAGSPRH---R-----S-
-----PRGQALVSPRTPTSKVVPYAKDQAPAGSGGSQT-PHSQFLI--------------
------------------------------------------------------------
------------------------------------------------------------
------------------V-----------------------------------------
---------------------------------------------------------NLS
SPPASRNDSE--S-NGESLPELEDPDSTE----PQTAPPQA---HSVGSGEEAVNKAKQS
RSEKKARKAMSKLGLRQ--IHGVT----RITIRKSKNILFVISKPDVFKSPASDIYIVFG
EAKV--------------------------------------------------------
------------------------------------------------------------
----------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
EHCVLT-PKPSALALTFLPSKPGARPPPDGASWDAGPGRAPSAWAVQAEGDPS-------
-GPEVRPAESPLPASLEPRIVMGEETCRA-SPLP---------------RATLPELRDWE
G-GHASLNPPPELCSQGDPPVPFPAPDSDSYFTPPSTPTETASTLLPGPGPHREAQ--DA
QAE----LGNSPPASPSGSYITADGDSWAS------SPSCSVSLQAPAEGLDVPSGWGFS
PPGSVA--------------DERELPPAGTPDTSSPESSLSADSSSSWGQE---GHFFEL
DFLANDXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----------XX--------
-------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-----------XXXXXXX-XX
XXXXX-XXXXXXXXXX----X--X----------------------XXXXXXX-----XX
XXXXXXXXXXXXXXXXXXX-----XXXXXXXXXXXXXXXXXXXXXXX-------------
--------------------------------------------XXXX------------
----------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------------
-XXXXXXXXX---------------------------------------------XXX--
-------------------------------------XXXXXXXXXXX-XXXXX---XXX
X----------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---XXXXXXX----
-------------------------------XXXXXXX----------------------
---------------XXXXXXX----------------------------XXXXXXXXXX
XX-------------------------XXXXXX-------------XX------------
--------------------XX-----XX--XXXX----XX------XXXXX--------
---XXXXXXX------XXXXXXXXX-X----------XXXXXXXXXXXX--X--------
------------------------------------------XXXXX---------XXXX
XXX-------X---XX------------------------------XXXXXXXXXXXXXX
XXXXX------------------XXX--XX--------------X--------------X
XXXXXXXXXXXXXXX--XX--------X-------------XXXX---------------
------------------------------------------------------------
-----------------XXXXXXXXXXXXXXX----XXXXXPALQDADLP--LVQRSPKA
--PEPQPE-EVDTAFPSLQDAGLPSVQRSASEPSPEPQSEEVDLTASPPLQDAGLHSGQE
LASEASPEPQSEEVDLTASLSLQDAGLPS-------------------------------
------------------------------------------------------------
------------------------------------------------DQGSASEASP--
--EPQPEEVDL---TASPPLQDAGLPSGQELASEA-------------------------
------------------------------------------------------------
------------------------SPEPQ-------------------------------
------------------------------------------------------------
-----------SEEVDLTASLPLQDAGLPSGQGSAS-------KASP-QALQADTGYTL-
--------GTEPMATTAQ-------------QK--GGKTLELRPAPEKRDPDHTG-----
----------------GSDSLALDQIHLGGLEPA-------------ADARIPLDEAPG-
--------------------------PP-EPDSSREEVAKGLL-APEQGACPDARGHGGD
GAEPSSPLKEAPGAENQERGVLKA------------------------------------
---------SAPEPCPAASLEVGQVGPPSPVEEGR-----AALGPRLPVAVAAEAGLGSC
PGSPSG----AVPRLGGSCP-KDPALALPLPSRQP-------------------------
------------------------------------------------------------
-----------------------------------------------EPVRGLHSGQQAR
AALGVLSSSPPQPPQSPLGGLPGAPQASIQG----AE--SSAPGVLIXXXXXXXXXXXXX
XXXXXXXXXXXXXXXX---------XXXXXXX--X-XX------------XX-----XXX
XXXXXXX---XXXXXXXXXXX-XX-----------X------------------------
-------------------XXXXXXXXXXXXXXXXX------------------------
--------X--X--------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSP
QAPGSGQHSD--S-HGESSAELEEQDLSGPR--TAQCPAQA---PAGGGSEETVTKVKQS
RSEKKARKAMSKLGLRQ--IQGVT----RITIQKSKNILFVIAKPDVFKSPASDTYVVFG
EAKIEDLSQQVHRAAAEKFKVPSEPSALVPESAPGPRVRPECKEEE--E--DDDEEVDET
GLEVRDIELVMAQANVSRAKAVRALRDNQKDIVNAIMEKTM-------------------
----------------------------------------------

------------------------------------------------------------
------SA-LPLAFRSAWRGGARSLGLIGGRGSADVIH--APPSRGAVAELATPSALMDR
GTERQRDQQAHVQAMPGEAARAELLLPEAGGPGSRTDLSCDAAIAT-ILKGDQ------R
EPLALTPPGPSPLALTLLSSKPGARPQPEGASWDAGPSGAASTWVDPAEGSPSPGVLSEG
LPLQSLPAEVPLPTTLEPRIVMGEETCQV-IPSA---------------RAAWSVLRDPE
G-GHTALQPPPEPRSQGDPPVPSPPPDLDSYFTPPSTPTRTTYALLPDHGPHRDAW--DL
EAELLDELLDSSPASPSGSYITADGDSWAS------SPSCSLSLLAPAEGLDFPSDWGLS
PSGSVV--------------DELEPHPTEYPEPRSSESSLSADSSSSWSQE---GHFFDP
TFLANDPMIPAALLPFRGSLIFQVEAVEVTPLSQEEGEEE---------AAAGAATPDGD
-LAGEAEDDSTSASFLQSLSDLSIIEGMDEAFAFRDDTSAASSDS--DSASYAGADDDDG
LYSEEPHAQPSAQSREQEHRGR------------------------TSFQGAE-----FM
PQISEP-EACLTNSQESIA-----EIAEEAPTLGMGSEATVPLPDLQ-------------
------------------------------------------------------------
--------------AAPGPQVEEATTVTPRVENK-VDSAALQAPRAL-------PEPCRK
GMSTTLGCKTVTA----------------------ETILDLQEVASPTLYPILPANLKEG
G--------------------------------------QGLPSTPEY-VAVGSVRSQKV
EGGVTIPQDLPMTLSPFLQ-GVDPTS----------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------------GPEAV
EVVTLRLQWDEGCVIALQEVPAGSPPPLPSTKPTSGPESRA------VATCGPQQAKEGS
TA-PQDSPTA------STPPLQGSE-P----------TSEP--EAVVTL--ESQQ-DEG-
------------IATAPQDSPTAPTPPLQGSE----------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------PTSDPEPELAVTLGPPQAKG----GVTIPQLAPAASPS----------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----PLQNLDSMSDLQPEAVVTMGSQQAKGS-----------------------------
------------------------------------------------------------
-----------------------------------------ATAPQDTLVVAPPSLQGTD
------------------------------------------------------------
------------------------------------------------------------
---------------------------STS-------EPELIVQD-TSPALQRETCYTP-
--------ETKPSASEAH-------------QE--LGVALGPKPVPEEQGSEAPL-----
----------------DPALPASNQAQQNGSQPAVNTDSPGAPEES--------------
----------------CPTLST---MVSEPTSCLGENVAESMP-ALRQG----ACLEAHD
GVKTSSPQRQVP--KNKRGRGPKPPGQGNG-T-----KSASQG-----------------
--AGE-----TSKAQSAACAEVSQTQG---------LSSKDTLGPKLPVALCVQARLGSC
PGSPAG----ATCTLSRVHS-EETARAA--------------------------------
------------------------------------------------------------
-----------------------------------------PSFEQLEPVLTLGSREQPQ
TTPGALNPFPA----NSASDLPTTSQGRPLD----PD--PPAPSALDRASQTSPGPPAPC
LCPTSQKAYVED--SPASGGLMP-RAGAQGAA--AITTSGSTMPLGARQRVNLSPHCT-L
NPKVTPT---DAKDLACIISSPCQVPPPSGTQNPSG------------------------
-----------------PRGFTAHE-QEDEDSLEEGNHMWGSGPG---------------
-----------------------------------------------PRPSYLTPSPDSQ
RAPGSGQHSD--S-RGESPTELDEQDTP-PQ--KGQCPAQG----PAGSNDDTTAKAKQS
RSEKKARKAMSKLGLRQ--IQGVT----RITIQKSKNILFVIAKPDVFKSPASDTYVVFG
EAKIEDLSQQVHKAAAEKFKMPSESSALVPELAPGPRVRPECEEQE------EDEEVEEA
GLELRDIELVMAQANVSRAKAVRALRDNHSDIVNAIMELTM-------------------
----------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
--------------MPGEAARAEPLLPEAGRPGPRTESSCDVAVAT-TPRGDR------L
EHCALT-PGPSALALEFLPSKPGARPPPEGASWDAGPGGTPSAWVVPAEGDPSPG-----
-PPEAQPAGGPPPATLEPRIVMGEETRRV-PQPS---------------RAALPELRDRE
G-GYRSLDPSPELCSQGDPPVPCPAPDPDSYFTPPSTPTETASALLLGPGPRREAR--EA
PAE----PGDSPPASPSGSYITADGDSWAS------SLSCSLSLLAPAEGLDVPSGWGFS
PPGSVA--------------DEQELPPMGLPGPPSPESSISADSSSSWGQE---GHFFEL
DFLANDPMIPAALLPFRGSLIVQVEAVEVTPRAPEDD--------E---QEEDIPVPGED
-PAGEGEDDSTFASSLQSLSDLSITEGMDEAFAFRDDTSAASSDP--DSASYAGADD-ER
LYSEEPHARPAALLPD----SPGE----------------------PAP-----------
-AVSEGGAGRATESQEPGA-----QVPEAGHASGQASAA-AAA-----------------
------------------------------------------------------------
---P------HTPQEAPGL-----TLVTPQAWGEEADSALGPTPIAA---GTAQPLREDD
STALGPGPWTTPEEGALTPSPDSLQ------------------------------NPEKE
AGQ----------------------------------DDVGLPSGQAP-TAEVSPVPQPG
EADRTSPQDPDSVATLLSLQDEGLPSGQGTPTEARLQTLQVDAGCV-PAIEPVVTA--AQ
PATEA-------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------PETPE------PATEALQHPKPATEA------VEF---------------
-----------PEPDTEATNCPKPVTEAP-------------------------------
------------------------------------------------------------
ECPEPVTEAVECLESATEALE--CPEPAME---------APEH----SKP-------ATE
APECPEPAT-EAIECLESA----------IE-----------------------ALEYPE
PATEALKC-------------PQPAME---------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------APECPEPATEAPEYSETTTEALEH-SEPATE-----
--------DPEHPEPATEAPECPELATEDPEFPEPATEALEHSEPAMEDPEHPEP-----
-------------------------------------------------------VTEAP
KWPEP----------------ATEAPECLEPATEAPEHSEPATEAPELPELTTEASECPE
LATEAPEHPEPATE-ALEHSEPAMEAPELPELI----------MESP-EVPEPATEAPE-
--------CPEPVSEAPE------------CLE--PATEAPECPEPAT----------EA
LERSEPAMEPPECPESATEALA-------------------------PERPEPVSEAPER
PEPVLEAPECPEPATGPPRPAVEATDPH-KPASIGEEVEEGLL-APELGTCPGACVCAGD
GAETHLPQKEAPGGENQGAGGL---------------ESAPQG-----------------
--ARKAPGDCGPEVHPAACPEVGHAWPQSPAEEGE-----ANPEPRSPVAVASEAGLGSC
SEFPPR----SVPRPGRRCP-KEPGPTSPAPSQQP-------------------------
------------------------------------------------------------
-----------------------------------------------EPMLGRGSGEWMQ
IAPGSPSSSPPQAPKSPARVLPSVPQDRLLS----PE--PSVPGVPTEAAPYPMAPLTSC
PCQGPREDSAEGKEPLGSLGLQPPRAGAQRAV--A-AFSGTTKPPGAGHRVSLPPHSPLL
SPKMAPTGDTHAKDQAWRISPPCQVPP--------S------------------------
-----------------PRGLLAAEQQDDQDSLEED------------------------
---------------------------------------------------------SPP
RAPGSGQHSD--S-HGESSAELEEQDLSGAQ--TAQCPAQA---PAGGSSEETVAKAKQS
RSEKKARKAMSKLGLRQ--IQGVT----RITIQKSKNILFVIAKPDVFKSPASDTYVVFG
EAKIEDLSQQVHRAAAEKFKVPTEPSALVPESAPGPLVRPECEEEE--EE-EEEEEVDEA
GLELRDIELVMAQANVSRARAVRALRDNQSDIVNAIMELTM-------------------
----------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------QTVPPQAQLA---YSVGS-EKTINKAKQS
QNEKKAQKDISKLGLLQ--IHKVT----RITIQKFKNILFVISNPDVFKNLASEIYIVFG
EVKIEDLSKQVHKAKVEKFKVPAELSPIITETAIGLSIKEES-----------DEEEVDK
GLEICDIELVMAQANVN----------NNNGIINAIMELTT-------------------
----------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-MHSLRETSAVT-----LLGITKPGP-----RQRG-------------------------
--------------------------------------------------------CESL
SHRGSCNDTE--S-NDESLPELEEPDV-TEPRTSSSQNQLA---HCVAPGEESISKAKQS
RSEKKARKAMSKLGLRQ--IHGVT----RITIRKSKNILFVITKPDVFKSPASDIYIVFG
EAKIEDLSQQVHKAAAEKFKVPMEHSPLITETTPTLTIKEE---S------EEEEEVDET
GLEVRDIELVMAQANVSRAKAVRALRHNNNDIVNAIMELTM-------------------
----------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-------------------------------PSVSTDLSCDAAEAT-TPKGDR------L
EHCALT-SGPSTLALTFLHGKPGARPPPEGASWDAGPGRAPSAWTVQAEGGPSPG-----
-PAEVRPTEGPLPASLEPRIVMGEETCQA-APLP---------------RATMPELRDWE
G-GHANLNPPPEFCSQGDPPVPFPAPDSDSYFTPPSTPTKTASTLLPGPGPHRDAQ--DA
QAE----LGDSPPASPTGSYITADGDSWAS------SPSCSLSLQALAEGLDVPSGWGFS
PSGSVV--------------DERELPPAGTPDSSSPESSLSADSSSSWGQE---GHFFEL
DFLANDPMIPAYLLPFQGSLIFQVEAVEVTPLPHEEEEVEEE-EQE---EEQEVPLPRGD
-LAGEGEDDSTFASSLQSLSDLSITEGVDEAFAFRDDTSAASSDP--DSASYTGADD-ER
LYSGEPHAQPATLLQD----SPGE----------------------AASWGPE-----PS
STP---------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------QD------------------------
--------AGLPLVQGSASEASPESQSEEDLTASSTPQDAGLPLVQES-ASEVSPEPQSE
E----------DLTASLPLKDESLPLVQGSASEASPEPQSE-------------------
----------------------------DLTASLPLKDEGLPLVQGSASE----------
-ASPEPQS---EEDLTASP-----------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------PLQDTD-L----------PLVQGSVSEASP--EPQS-EE--
------------DLTASPPLQDAGLPLVQGSVSEVSPEPQSEEEDLTASPPLQDAGLPLV
QGSASEASPDHQSDLKASPPLQDAGLPLVHGPASEASPEPQSEEEELTASLPLQDTGLHL
VQGSAFKASP--------------------------------------------------
------------------------------------------------------------
-------ELQSEEE----------------------------------------------
-----------------GSVSEASTEPQSEEE----ELTASLHLQDTGFS--LVQGSASD
ASSEPQSEEEELTASSHL------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------QDAGLP
LVHGSASEASPEL-----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------HQVS-------ATSASP-QALMTDTGCTQ-
--------KTEPTTTAAH-------------RK--GRKTLGLRPAPEERDPDHTG-----
----------------GSDSLALDQIHLGGPDLP-------------ADARTPLEGDAGP
SKPATEIPDTP----------------------SGEEVAEGIL-APEQEACHDICAHGGD
GAESSSPPKVALGVEHQGHEAL---------------KPVVH------------------
----------GPGVCPTASLEVGQLGPPSPVEEGR-----ATLGHRLPMAVGSEAGLGSC
SQSPSR----AVPRLGGHCA-KDPAPTSPLPLRQP-------------------------
------------------------------------------------------------
-----------------------------------------------KPVLGPGKGERAQ
AALGVLGPSPLQPPESPIGGLPSAPQDRIQG----PE--PPAPGILMEAVPTPLASPAPC
PCRGPREDLVEGAEPLGSPSHPPPRPRAQRAV--A-ASSGITNPPGAGQ-VSLPPHPTLL
SPKAAPKRGTHAKDPASRLSPPRQVPPGSGPRSPAG------------------------
-----------------PRGLPATEQQDDGDSLEEGGQRAGQG--CQSCSPRA-------
-------------------------------------------PVQKGRPSSHSPSSDSP
RALGSGQHSD--S-HGESSAELEEQDLPGPQ--TAQCPAQA---PAGSGSEETVAKAKQS
RSEKKARKAMSKLGLRQ--IQGVT----RITIQKSKNILFVIAKPDVFKSPASDTYVVFG
EAKIEDLSQQVHRAAAEKFKVPSEPSALVPESAPGPRVRPECEEEE--EE-EDEEEVDEA
GLELRDIELVMAQANVSRAKAVRALRDNQSDIVNAIMELTM-------------------
----------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
---------------PGEAARAELLLPEADRPGPRTDLSCDAAAATTILGGDR------R
DPCALT-PGPSHLALTFLPSKPGARPQPEGASWDAGPGGAPSAWADPGEGGPSPMLLPEG
LSSQVLSTEAPLPATLEPRIVMGEETCQA-LLSP---------------RAARTALRDRE
G-GHTSPDPPPELCSQGDLSVPSPPPDPDSFFTPPSTPTKTTYALLPGCGPHGDAR--DS
EAELRDELLDSPPASPSGSYITADGDSWAS------SPSCSLSLLAPAEGLDFPSGWGLS
PRGSMV--------------DERELHPAGTPEPPSSESSLSADSSSSWGQE---GHFFDL
DFLANDPMIPAALLPFQGSLIFQVEAVEVTPLSPEEEEEE----------AVADPDAGGD
-LAGEGEEDSTSASFLQSLSDLSITEGMDEAFAFRDDTSAASSDS--DSASYAEADD-ER
LYSGEPHAQAT-LLQDSVQKTEEESGGGAKGLQAQEG---------TVSWALE-----AA
PQTSDRGAY-LSQRQESIS-----EVTEEGLALGQESTATVTPHILQ-------------
------------------------------------------------------------
--------------VAPGLQVEAATRVTPQAGEEEADSTAGQESAAMAM-----PQPSQE
GISEILGQESVTA--EKLPTPQE--------------------ETSLTLCPDSPQNLKEE
-G-------------------------------------LNLPSGGKP-VAAATIVPRQA
EEDLTLPQDSA-MTPPLPLQDTDLS-----------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--SAP-------------KPVAAATLVPQ-------------------------------
-----------------------------------------------------Q------
----AEEGLTLPQDSAMTPPLPLQDTGPTSGP-------EPLAVATP-QSWQAEAGCAP-
--------GTEPVATMAQ-------------QE--VGAALGPRPAPEEKNAALPT-----
----------------VPEPAALDQVQQDDPQPA-------------AEAGTPWAAQEDA
DS----------------TLGMEALSLPEPASGAGEEIAEALS-RPGREACLEVRAHTGD
GAKPDSPQKEALEVENQQEGGLKPLAQEHG-P-----RSALGG-----------------
--AGE-----VPEAPLAACPEVSQARLLSPAREERGLSGKSTPEPTLPSAVATEASLDSC
PESSVG----AVARLDRGCP-DAPAPTSAPTSQQPE------------------------
------------------------------------------------------------
------------------------------------------------PVLGLGSVEQPH
EVLSVLGTPLLQPPENLAKGQPSTPADRPLG----PD--PSAPGTLAGAALPPLEPPAPC
LCQDPQEDSVEDEEPPGSLGLPPPQAGAQPAA---AAVSGTTQPLGTGPRVSLSPHSPLL
SPKVASM---DAKDLALQILPPCQVPPPSGPQSPAG------------------------
-----------------PQGLSAPKQQEDEDSLEE-------------------------
---------------------------------------------------------DSP
RALGSGQHSD--S-HGESSAELDEQDILAPQ--TVQCPAQA----SAGGSEETIAKAKQS
RSEKKARKAMSKLGLRQ--IQGVT----RITIQKSKNILFVIAKPDVFKSPASDTYVVFG
EAKIEDLSQQVHKAAAEKFKVPSEPSALVPESAPRPRVRLECKEEE--E--EEEEEVDEA
GLELRDIELVMAQANVSRAKAVRALRDNHSDIVNAIMELTM-------------------
----------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
--------------MPGEAARAELLLPEADGPGPRTDLSCDAAAATSILGGDR------R
EPCALT-PGPSHLALTFLPSKPGARPQPEGASWDAGPGGASSAWADPAEGSLSPKLLPEG
LS-QVLPTETPLPATLEPRIVMGEETCQA-LLSP---------------RAARTALRDQE
G-GHESLDPPPELCSQGDLSVPFPPPDPDSFFTPPSTPTKTIYALLPGSGPLGDVQ--DS
EAEMQDELLDSSPASPSGSYITADGNSWAS------SPSCSLSLLAPDEGLDFPSGWGLS
PQGSMA--------------DERELHPAGTPESQSSESSLSTDSSSSWGQE---GHFFDL
DFLANDPMIPATLLPFQGSLIFQVEAVEVTPLSPEEEEEE----------VEAAPSPGGD
-LAGDGEEDSTSASFLQSLSDLSITEGMDEAFAFRDDTSAASSDS--DSASYAEADD-ER
LYSGEPHAQPT-LLQDSVQKTEEESGGGAQGLQALEG---------TEFWALE-----AV
SQTSDRGAH-LSQRQESIS-----EVTEEGLALGQQSTATVTPHTLQ-------------
------------------------------------------------------------
--------------VALGLQVEVATRMIPQAGEEEVDSTTGQAPAAMAM-----PQPSQE
GISEILGQESVTAEK--LPTPQE--------------------AASLTLCPDSPQNLK--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------EGGGLDLL
SG------------------------------------------------------PKPV
ATATLVPQQAEEGLTLPQDSAVTPPLPPQDTDLPSGPEPVA------VATLVPQQAEEGL
TL-PQDSAVT------PPLPPQDTD-X----------XXXXXXXXXXXX--XXXX-XXX-
------------XXXXXX------------------------X-------------XXXX
XXX-------X-----------------------------------XXXXXXXXXXXXXX
XXXXX-------------------XXXXX-------------------------------
XXXXXXXXDMIXXXXXXXXXX--------------------XXXX-X-------------
-------------XXXXX--XXXXXX-----------------XXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXPVPQQAEE----GLTLPQDSAV--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------PPATLVPQQAEDG----------LT------------LPQGSAVLPPLPPQDTD
LPSGP-------------EPVAAAMLVPQ----Q--------------------------
------------------------------------------------------------
----AEEGFTLPQDSAMTAPLPLQDTGPTSVP-------ELLAVATP-QTLQAEGDCAP-
--------GTESVASMAQ-------------QE--VGAALGPRPAPEENVALPR------
----------------VPEPVALDQVQQDDPQPA-------------AEAGTPWAALEDV
GP----------------TLGLEAPHLPEPASGVGEEEVAEALSMPKWEACLGARANTGD
GD---LASKETLEVENQQGGGLKPPARECE-P-----GSALGG-----------------
--AGE-----VPKVAPAACPEVGQARLLSPTREGRGPSVKSNLEPRLPSAVATEACLDSC
PESSAG----AVSRLDRGCP-EAPAPTSVPTFQQP-------------------------
------------------------------------------------------------
-----------------------------------------------EPVLGLGSVEQPQ
EAPSVLGPHLLQLPENLAKGLPSVPLDGLLG----PD--PSVPGVLAEAALPPLDPPAPC
LCQDLQEDSVEDKEPPGSRGRLSPQAGAQPAT---VAVSGTTQPLGIGLGVSLSPHSPLL
SPKVAPT---DAKDLALQISLPCQVPPRSGPQSLTG------------------------
-----------------PQGLSAPEQQEDEDSLEED------------------------
----------------------------------------------------------SP
RVLGSNQHSD--S-HGESSAELDEQDILAPQ--TAQCPVQA----PAGGSEETIAKAKQS
RSEKKARKAMSKLGLRQ--IQGVT----RITIQKSKNILFVIAKPDVFKSPASDTYVVFG
EAKIEDLSQQVHKAAAEKFKVPSEPSALVPESAPRPRVRLECKEEE--E--E-EEEVDEA
GLELRDIELVMAQANVSRAKAVRALRDNHSDIVNAIMELTM-------------------
----------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
--------------MPGEAARAELLLPEADGPGPRTDLSCDAAAATTILGGDR------R
EPCALT-PGPSHLALTFLPSKPGARPQPEGASWDAGPGGAPSAWADPVEGGPSPKLLPEG
LS-QALPTEVPLSATLEPRIVMGEETCQA-LLSP---------------RAARTALRDQE
G-GHTSLDPPPELCSQGDLSVPFPPPDPDSFFTPPSTPTKTTYALLPGSGPHGDAQ--DS
EVEMQDELLDSPPASPSGSYITADGDSWAS------SPSCSLSLLAPDEGLDFPSGWGLS
PQGSMA--------------DERALHPAGTPEPQSSESSLSADSSSSWGQE---GHFFDL
DFLANDPMIPAALLPFQGSLIFQVEAVEVTPLSPEEEEEE----------VEAAPGAGGD
-LAGEGEEDSTCASFLQSLSDLSITEGMDEAFAFRDDTSAASSDS--DSASYAEADD-ER
LYSGEPHAQPT-LLQDSVQKTEEESGGGAEGLQALEG---------TLSWALE-----AV
SQTSDRGAR-LSQRQESIS-----EVTEEGLALGQESTATVTPHTLQ-------------
------------------------------------------------------------
--------------VALGLQVEVATRMTPQAGEEEVDSTAGQTPAAMAA-----PQPSQE
GIGEILGQESVTAEK--PPTPQE--------------------EASLALCPVSPQNSK--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------EEGGLDLP
SG------------------------------------------------------PEPV
ATATL-------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------VPQ----Q--------------------------
------------------------------------------------------------
----AEEGLTLPQDSAVTAPLPLQDTGPTSVP-------EPLAVATP-QTLQAEAGCTP-
--------GTESVASMAQ-------------QE--VGTASGARPAPEKNVALPR------
----------------VPEPAALDQVQQDDPQPA-------------ADAGTPWAALEDA
GP----------------TLGLEAPHLPEPASGVGE-EGAEALSMPEREACLGAGAHTGD
GD---LPPEDTLEVENQQEGGLKPPAQECG-P-----GSALGG-----------------
--AGE-----LPEAPPAACPEASQAQLLSPAREGSGPSGKFTLEPGLPSAVATEACLDSC
PESSVG----AVSRLDRGCP-EAPAPTSAPTSEQL-------------------------
------------------------------------------------------------
-----------------------------------------------EPVLGLGSVEQPQ
EAPSILGPHLLQPPENLAKGVPSVPLDRLLG----PD--PSVPGILAEAALPPLEPPAPC
LCQDPQEDSVEGKEPPGSLGLPPPQAGAQSAT---VAVSGTTQPLGIGLGVSLSPHSPLL
SPKVAPT---DAKDLALQISLPCQVPPRSGPQSPAG------------------------
-----------------PQGLSAPEQQEDEDSLEED------------------------
----------------------------------------------------------SP
RVPGSNQHSD--S-HGESSAELDEQDILAPQ--TAQCPAQA----PAGDSEETTAKAKQS
RSEKKARKAMSKLGLRQ--IQGVT----RITIQKSKNILFVIAKPDVFKSPASDTYVVFG
EAKIEDLSQQVHKAAAEKFKVPSEPSALVPESAPRPRVRLECKEEE--D--EEEEEVDEA
GLELRDIELVMAQANVSRAKAVRALRDNHSDIVNAIMELTM-------------------
----------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
--------------MPGEAARAELLLPEADGPGPRTDLSCDAAAATTILGGDR------R
EPCALT-PGPSHLALTFLPSKPGARPQPEGASWDAGPGGAPSAWADPGEGGPSPMLLPEG
LSSQALSTEAPLPATLEPRIVMGEETCQA-LLSP---------------RAARTALRDRE
G-GHASPDPPAELCSQGDLSVPSPPPDPDSFFTPPSTPTKTTYALLPGCGPLGDAG--DS
EAELWDELLDSPPPSPSGSYITADGDSWAS------SPSCSLSLLAPAEGLDFPSGWGLS
PQGSMA--------------DERELHPAGTPEPPSSESSLSADSSSSWGQE---GHFFDL
DFLANDPMIPAALLPFQGSLIFQVEAVEVTPLSPEEE-EE----------AVADPDPGGD
-LAGEGEEDSTSASFLQSLSDLSITEGMDEAFAFRDDTSAASSDS--DSASYAEADD-ER
LYSGEPHAQAT-LLQDSVQKTEEESRGGAKGLQVQEG---------TVSWALE-----AA
PQTSDRGAH-LSQRQESIS-----EVTEEGLALGQESTATVTPHTLQ-------------
------------------------------------------------------------
--------------VAPGLQVEVATRVTPQAGEEEADSTTGQASAAMAM-----PQPSQE
GISEILGQESVTA--EKIPTPQE--------------------ETSLTLCPDSPQNLKEE
GG-------------------------------------LDLPSGPKP-VAAALLVPQQA
EEDLTLPQDPA-MTPPLPLQDTDLSSAPKPVAAATTVP----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------RQAEEGLTLPQDPAVTPPLPLQDTDLSSAPKPVA------AATTVPRQAEEGL
TL-PQDPAVT------PPLPLQDTD-L----------SSAPKPVAAATT--VPRQ-AEE-
------------GLTLPQDPAVTPPLP---------------------------------
-----------------------------------------------------------L
QDTDL-S-------------SAPKPV-------------------------AA---ATTV
PRQAEEGL----------------------------------TLP---------------
---------------------------------------------------------QDP
AVTPPLPLQDTDLSSAPKPVAAATTVPRQAEE----GLTLPQDPAV--------------
--------------------------------------------TPPLPLQDADLSSAPK
PVAAATTVPRQAEEGLT-------------------------------------------
---------------------------------------LPQ--------------DPAV
TPPLPLQDTDLSSAPKPVA-----------------------------------AALL--
--V---------------------------------------------------------
------------PQQVEEDLT----------LP------------QDSAMIPPLPLQDTD
LSSAP-------------KPVAAATIVPR-------------------------------
-----------------------------------------------------Q------
----AEEDLTLPQDSAMTPPLPLQDTGPTSGP-------KPLAVATP-QTLQAEAGCTP-
--------GTEPVATMAQ-------------QE--VGAALGPGPAPEEKNAALSR-----
----------------VPEPAALDQVQQDDPQPA-------------AEAGTPWAAQEDA
DS----------------TLGVEALCLPEPASGAGEDVAEAPS-RPGWEVCLEGLVHTGD
GAKPDSPQKDTLEVENQQGEGLKPPAQEHG-P-----GSALGG-----------------
--AGE-----VPEAPPAACPEVGQAWLLSPAREGRGLSGKSTLEPTLPSAVATEASLDSC
PESSVG----TVSRLDRGCP-DAPAPTSAPTSQQPE------------------------
------------------------------------------------------------
-----------------------------------------------PPVLGLSSVERPH
KAPSVLGPLLLQPPDNLGKGLPSAPPDRPLG----PD--PSAPGTLAVAALPPLEPPAPC
LCQDLQEDSVEEEEPPGSLGLPPPQAGAQPAA---AAVSGTTQPLGTGPRVSLLPHSPLL
SPKVASM---DAKDLALQISPPCQVPPPSGPQNPAG------------------------
-----------------PQGLSAPEQQEDEDSLEE-------------------------
---------------------------------------------------------DSP
RALGSGQHSD--S-HGESSAELDEQDILAPQ--TAQCPAQA----PAGSSEETIAKAKQS
RSEKKARKAMSKLGLRQ--IQGVT----RITIQKSKNILFVIAKPDVFKSPASDTYVVFG
EAKIEDLSQQVHKAAAEKFKVPSEPSALVPESAPRPRVRLECKEEE--E--EEEEEVDEA
GLELRDIELVMAQANVSRAKAVRALRDNHSDIVNAIMELTM-------------------
----------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
--------------MPGEAARAELLLPEAGGPGPRTDLSCDAAAAT-IPRGDR------R
EP-VLT-PGPSPLALTFLPSKPGTRPQPEGASWDAGPHGAPSAWADPAEGGPSPALLPEG
LPPQALSSEAPLPGTLEPRIVMGEETCQA-LLSP---------------RAAQPALRDWE
GGGPASLNPPPESCSQDDPSVPSPPPDPDSYFTPPSTPTKTTYGLLPGRGPHRDTW--DS
EAELLEELLDSPPASPSGSYITADGDSWAS------SPSCSLSLLAAAEGLDFPSGWGLS
PTGSVM--------------DERELHPAGPPGPPSSESSLSVDSDSSWGQE---GHFFDL
DFLANDPMIPAALLPFQGSLIFQVEAVEVTPLPAEEEEEEEE--------EVAAPDPAGD
-LAGEGEEDTTSASFLQSLSDLSIMEGMDEAFAFRDDTSGACSDSDSDSTSYAGADD-ER
LYSGEPHAQPTALPPDGTQKAEEEGGGGAEGPQAQEE---------ATLRDPE-----AA
PQVSGEE-AHLSQSQESIL-----ETSEEGLVVGQESAATVSPHTLQ-------------
------------------------------------------------------------
--------------AAPGLQVEAATRVTPQAGEEEADSTTGQAPAAGAM-----PQPSWE
GISAALQQGPVPAET----------------------PATPQEEASLTLCPDPPQNLKGE
GG-------------------------------------PGLPSGPKP-VTAATPMPPQA
EEGLPLHQDC--------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------AMAAPLPLP-------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------DEGLPSGPKPVTAATPMPPQAEE----GLPLH-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------QDCAMAAPLPLPDEGPPSGQ-------EPVAAGTP-QALQAAAGCAP-
--------ETEPMASMAQ-------------EE--VGVALGLRPAPDEKDAALPR-----
----------------GVEPPALDQVQQDDPEPAAEAEAPGAAH----------------
-------------EDACPTLGTEVPDAPEPVSGAGEELAEGLP-VPEWEACLEARVQTGD
GAEPHSAPKEALGAENQREGGPEPPAQGHG-P-----GEVPQG-----------------
--AGE-----APEAHPAACPEADQAPPLSPAREGRGP--EPTPGPRLPTAAAAEAGLGSC
PESPAGTPAGTASGPDRGCP-EEPAH--MS------------------------------
------------------------------------------------------------
----------------------------------------IPPSQQLEPALGLGSGEQLQ
AASRAVSPSSPEPPESPARGLPSAPQDRLPG----PD--TSTPGVLARASPPPLEPPAPC
LCQDPQEDSMEDEEPPGSPGLPPPQAGAQPAA---AAVSGTSQPPGTGQRVSLSPHSPLL
SPRAAPT---EAKDLALRILPPCQVPPCSGPRSPAD------------------------
-----------------PQELPASEQQEDEDSLEED------------------------
----------------------------------------------------------SP
QALGSGQHSD--S-HGESSAELDEQDISAPQ--TTQCPAQA----PTGSSEETIAKAKQS
RSEKKARKAMSKLGLRQ--IQGVT----RITIQKSKNILFVIAKPDVFKSPASDTYVVFG
EAKIEDLSQQVHKAAAEKFKVPSEPSALVPESAPRPRVRPECEEEE--E--EEDEEVDEA
GLELRDIELVMAQANVSRAKAVRALRDNHSDIVNAIMELTM-------------------
----------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
--------------MPGEAARAELLLPEADGPGPRTDLSCDAAAATTILGGDR------R
EPCALT-PGPSHLALTFLPSKPGARPQPEGASWDAGPGGAPSAWADPGEGGPSPMLLPEG
LSSQALSTEAPLPATLEPRIVMGEETCQA-LLSP---------------RAARTALRDRE
G-GHASPDPPAELCSQGDLSVPSPPPDPDSFFTPPSTPTKTTYALLPGCGPLGDAG--DS
EAELWDELLDSPPPSPSGSYITADGDSWAS------SPSCSLSLLAPAEGLDFPSGWGLS
PQGSMA--------------DERELHPAGTPEPPSSESSLSADSSSSWGQE---GHFFDL
DFLANDPMIPAALLPFQGSLIFQVEAVEVTPLSPEEE-EE----------AVADPDPGGD
-LAGEVEEDSTSASFLQSLSDLSITEGMDEAFAFRDDTSAASSDS--DSASYAEADD-ER
LYSGEPHAQAT-LLQDSVQKTEEESRGGAKGLQVQEG---------TVSWALE-----AA
PQTSDRGAH-LSQRQESIS-----EVTEEGLALGQESTATVTPHTLQ-------------
------------------------------------------------------------
--------------VAPGLQVEVATRVTPQAGEEEADSTTGQASAAMAM-----PQPSQE
GISEILGQESVTA--EKIPTPQE--------------------ETSLTLCPDSPQNLKEE
GG-------------------------------------LDLPSGPKP-VAAALLVPQQA
EEGLTLPQDPA-VTPPLPLQDTDLSSAPKPVAAATTVP----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------RQAEEGLTLPQDPAVTPPLPLQDRSLVSPEA----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------CG-------------------------------
-----------------------------------------------------C------
----KHRSLVSPEDSAMTPPLPLQDTGPTSGP-------KPLAVATP-QTLQAEAGCTP-
--------GTEPVATMAQ-------------QE--VGAALGPGPAPEEKNAALSR-----
----------------VPEPAALDQVQQDDPQPA-------------AEAGTPWAAQEDA
DS----------------TLGMEALCLPEPASGAGEDVAEAPS-RPGWEACLEGLVHTGD
GAKPDSPQKDTLEVENQQGEGLKPPAQEHG-P-----GSALGG-----------------
--AGE-----VPEAPPAACPEVGQAWLLSPAREERGLSGKSTLEPTLPSAVATEASLDSC
PESSVG----TVSRLDRGCP-DAPAPTSAPTSQQPE------------------------
------------------------------------------------------------
-----------------------------------------------PPVLGLSSVERPH
KAPSVLGPLLLQPPDNLGKGLPSAPPDRPLG----PD--PSAPGTLAVA-----------
---DLQEDSVEEEEPPGSLGLPPPQAGAQPAA---AAVSGTTQPLGTGPRVSLLPHSPLL
SPKVASM---DAKDLALQISPPCQVPPPSGPQNPAG------------------------
-----------------PQGLSAPEQQEDEDSLEE-------------------------
---------------------------------------------------------DSP
RALGSGQHSD--S-HGESSAELDEQDILAPQ--TAQCPAQA----PAGSSEETIAKAKQS
RSEKKARKAMSKLGLRQ--IQGVT----RITIQKSKNILFVIAKPDVFKSPASDTYVVFG
EAKIEDLSQQVHKAAAEKFKVPSEPSALVPESAPRPRVRLECKEEE--E--EEEEEVDEA
GLELRDIELVMAQANVSRAKAVRALRDNHSDIVNAIMELTM-------------------
----------------------------------------------

Query Results

"ENSGT00440000033468_1"

ENSGT00440000033468_1