Query Results 

-------------------------------------------MERQKRKADIEKGLQFI
QSTL-PL--KQEEYEAFLLKLVQNLFAEGNDLFREEDYKQALVQYMEGL-NVADYAASDQ
VALPRELLCKL

PF13181 // ENSGT00390000018542_0_Domain_0 (132, 162)

HV--NRAACYFTMGLYEKALEDSEKALGLDSESIRALFRKARALNELGR
HKEAYECSSRCSLALPHDENVTQLGQELAQ------KLGLRVRKAYKRPQ-ELETFSLLS
N--GTPTGV---------TDQGTSNGLGSIDDIE-----------------------TDC
YVDLRDSPALLPST------------------PTMPLFPHVLDLLAPLDGSSRTLPSTEG
LDDFSDADVFGPELDTLLDSL-----------SLVQGGLPGSGVPSELPQLIPVFPGGTP
LLPPVVGGSIPVSSPLPPASFGLVMDPSRKLAA-SVLDALDSPGPT-----LDPLD----
---LLPYSEAQL--DALDSFGS-ARGSLDKPDSFIEETSSQ--------D--HRPP----
--------S-----S-TQKPAP------------SPEPSMPNT----ALLIKNPLAATHE
FKQACQLCYPKT-GPRAGDYTYREGLEHKCKRDVLLGRLRSSEDQI-------WKRIRPR
PTKTSFVGSYYLCKDMINKQDCKYGDNCTFAYHQEEIDVWTEERKGTLNRDLLFDPLGGV
KRGSLTIAKLLKEHQGIFTFLCEICFDSKPRIISKGTKDCPSVCSNLAAKHSFYNNKCLV
HIVRSTSLKYSKIRQFQEHFQFDVCRHEVRYGCLREDSCHFAHSFIELKVWLLQQYS-GM
THEDIVQESKKYWQQMEAHAGKASS-SLGAPRTHGPSTFDLQMKFVCGQCWRNGQVVE-P
DKDLKYCSA--KARHCWTKERRVLLVMSKAKRKWVSVRPLPSIRNFPQ

PF00642 // ENSGT00390000018542_0_Domain_4 (949, 974)

QYDLCIHAQNGR
KCQYVGNCSFAHS

ENSGT00390000018542_0_Linker_4_5 (974, 1108)

PEERDMWTFMKE------------NKI------LDMQQTY---DMWL
-KKHNPGKPGEGTPISSREGEKQIQMPTDYADI---MMGYHCWLCGKNSNSKKQWQQHIQ
SEKHKEKVFTSDSDASGWAYRFPMGEF

PF00642 // ENSGT00390000018542_0_Domain_5 (1108, 1138)

RLCD-------RLQKGKACPDGDKCRCAHGQEE
LNEWLDRREVLKQKLAKARKDMLLCPRDDDFGKYNFLLQEDGDT----TAATPEAPIAAT
ATAATT---TTGE-----------------------------------------------
----------------------

-------------------------------------------MERQRRKADIEKGLQFI
QSTL-PL--KQEEYEAFLLKLVQNLFAEGNDLFREKDYKQALVQYMEGL-NVADYAASDQ
VALPRELLCK

PF13181 // ENSGT00390000018542_0_Domain_0 (131, 164)

LHV--NRAACYFTMGLYEKALEDSEKALGLDSENIRALFRKARALTELGR
HKEAYACSSRCSLALPHDESVTQLGQELAQ------KLGLRVRKAYKRPQ-ELETFSLLS
N--GTAAGV---------ADQGTSNGLGSIDDIET-----------------------DC
YVDLRGSPAPLPST------------------PTMPLFPHVLDLLAPLDSSSRALPGTES
LDDFSDGDVFGPELDTLLDSL-----------SLVQGGLPGGGVPSELPQLIPVFPGGTP
LLPPVVGGSIPVSSPLPPASFGLVVDPSKKLAA-SVLDALEPPGSG-----LDSLD----
---LLPYSETRL--DALDSFGS-SRGSLDKPSSFL----------EDANSQDHRPP----
--------S-----G-TQKPAP------------SPEPSMPNT----ALLIKNPLAATHE
FKQACQLCYPKT-GPRAGDYTYREGLEHKCKRDMLLGRLRSAEDQT-------WKRIRPR
PTKTSFVGSYYLCKDMINKQDCKYGDNCTFAYHQEEIDVWTEERKGTLNRDLLFDPLGGV
KRGSLTIAKLLKEHQGIFTFLCEICFDSKPRIISKGTKDSPSVCSNLAAKHSFYNNKCLV
HIVRSTSLKYSKVRQFQEHFQFDVCRHEVRYGCLREDSCHFAHSFIELKVWLLQQYS-GM
THEDIVQESKKYWQQMEAHTGKASSSLQGAPRTHGPSTFDLQMKFVCGQCWRNGQVVE-P
DKDLKYCSA--KARHCWTKERRVLLVMSKAKRKWVSVRPLPSIRNFPQ

PF00642 // ENSGT00390000018542_0_Domain_4 (949, 974)

QYDLCIHAQNGR
KCQYVGNCSFAHS

ENSGT00390000018542_0_Linker_4_5 (974, 1108)

PEERDMWTFMKE------------NKI------LDMQQTY---DMWL
-KKHNPGKPGEGTPVGSREGEKQIQMPTDYADI---MMGYHCWLCGKNSNSKKQWQQHIQ
SEKHKEKVFTSDSDASGWAFRFPMGEF

PF00642 // ENSGT00390000018542_0_Domain_5 (1108, 1138)

RLCD-------RLQKGKACPDGDKCRCAHGQEE
LNEWLDRREVLKQKLAKARKDMLLCPRDDDFGKYNFLLQEDGNA----PGAAPEAPATAA
GTGD--------------------------------------------------------
----------------------

------------------------------------------------------------
-STL-PL--KQEEYEAFLLKLVQNLFAEGNDLFREKDYKQALVQYMEGL-NVADYAASDQ
VALPRELLCKL

PF13181 // ENSGT00390000018542_0_Domain_0 (132, 162)

HV--NRAACYFTMGLYEKALEDSEKALGLDSESIRALFRKARALNELGR
HKEAYECSSRCSLALPHDENVTQLGQELAQ------KLGLRVRKAYKRPQ-ELETFSLLS
N--GTPAGL---------TDQGTSNGLGSIDDIE-----------------------TDC
YVDLRAPLSLLPSP------------------PTMPLFPHVLDLLAPLDGSSRTLPSTEG
LDDFSDADVFGPELDTLLDSL-----------SLVQGGLPGSGVPSELPQLIPVFPGGTP
LLPPVVGGSIPVSSPLPPASFGLVMDPSRKLAA-SVLDALDPPGPT-----LDPLD----
---LLPYSEARL--DALDSFGS-ARGSLDKPDPFIEETSSQ--------D--HRPP----
--------S-----S-TQKPAP------------SPEPSMPNT----ALLIKNPLAATHE
FKQACQLCHPKT-GPRAGDYTYREGLEHKCKRDVLLGRLRSSEDQI-------WKRIRPR
PTKTSFVGSYYLCKDMINKQDCKYGDNCTFAYHQEEIDVWTEERKGTLNRDLLFDPLGGV
KRGSLTIAKLLKEHQGIFTFLCEICFDSKPRIISKGTKDSPSVCSNLAAKHSFYNNKCLV
HIVRSTSLKYSKIRQFQEHFQFDVCRHEVRYGCLREDSCHFAHSFIELKVWLLQQYS-GM
THEDIVQESKKYWQQMEAHAGKACG-SLGAPRTHGPSTFDLQMKFVCGQCWRNGQVVE-P
DKDLKYCSA--KARHCWTKERRVLLVMSKAKRKWVSVRPLPSIRNFPQ

PF00642 // ENSGT00390000018542_0_Domain_4 (949, 974)

QYDLCIHAQNGR
KCQYVGNCSFAHS

ENSGT00390000018542_0_Linker_4_5 (974, 1108)

PEERDMWTFMKE------------NKI------LDMQQTY---DMWL
-KKHNPGKPGEGTPLSSREGEKQIQMPTDYADI---MMGYHCWLCGKNSNSKKQWQQHIQ
SEKHKEKVFTSDSDASGWAFRFPMGEF

PF00642 // ENSGT00390000018542_0_Domain_5 (1108, 1138)

RLCD-------RLQKGKACPDGDKCRCAHGQEE
LNEWLDRREVLKQKLAKARKDMLLCPRDDDFGKYNFLLQEDGDP----TAATPGAPTAAT
ATATTG---E--------------------------------------------------
----------------------

-------------------------------------LEPSIVMERQKRKQEIEKGLQLI
QSTL-PL--SQEDYEAVLQKLVRNLFAEGNDLFREKDFKLSLVQYVEGL-NVADYAASDE
VTIPKELLCKLHV--NRAACYFAMGLYEKALEDSEKALGLDKENIRALFRKARSLNELGR
HKEAYECNSRCLLSLPHDESVTQLGQELAQ------KLGLRVRKAYKRPQQELETFSLLS
NGTS--I---------NLSNQVHF-----IYI-----------------------HIDDC
SMDLQCLPAPVATSIPVSEGLSPLHSDSDAKGLPSS-LPAASLLPSP--ESVSL-PVPDS
VEDFTDGDIIGEELDSLLDSLAEGSP-YP-L-SLVQGSIPT-NLPTEMPQLIPVFPGGTP
LLPPVVTASIPVSTPLPPASFGLVMDPTKQLSSSSVLDAFEPPPGGSGGSTLDSLD--SL
DLL--PYTDSRL--DALDSFGT-SRGSLDALDSFAIEETSPQELRHPPGSQKPSPVVSEP
LPHADVPRCSGAKVS-LGGGSHPAVPKVTEHLLSQPEPVIPNT----ALLVKNPLASTHV
FKQACHICYPKT-GPKAGDYTYREGLEHKCKRDILLGRLKNSEDKT-------WKRIRPR
PTKTNFVGSYYLCKDMLNKQDCKYGDNCTFAYHQEEIDVWTEERKGTLNRDLLFDPLGGI
KQSNLTIAKLLKEHQGIFTFLCEICFDSKPRIISKGTKDTPSVCSNLSAKHSFHDNKCLV
HIVRSTSLKYSKIRQFQEHFQFDVCRHEVRYGCLREDSCHFAHSFIELKVWLLQQYS-GM
THEDIVQESKKYWQQMEAHASKPTNSM-ASPRAPTSSTFDLQMKFVCGQCWRNGQLVE-P
DKDLKYCSA--KARHCWTKERRVLLVMSKAKKKWVSVRPLPSIRNFPQ

PF00642 // ENSGT00390000018542_0_Domain_4 (949, 974)

QYDLCIHAQNGR
KCQYVGNCSFAHS

ENSGT00390000018542_0_Linker_4_5 (974, 1108)

PEERDMWTFMKE------------NKI------LDMQQTY---DMWL
-KKHNPGKPGEGTPLTSREGEKQIQMPTDYADI---MMGYHCWLCGKNSNSKKQWQQHIQ
SEKHKEKVFTSDSDSSCWSYRFPMGEF

PF00642 // ENSGT00390000018542_0_Domain_5 (1108, 1138)

QLCER-------FQKSKACPEGEECRYAHGQDE
LTEWLDRREVLKQKLAKARKDMLLCPRDDDFGKYNFLLRDGV------------------
------------------------------------------------------------
----------------------

-------------------------------------------MERQRRKADIEKGLQFI
QSTL-PL--KQEEYEAFLLKLVQNLFAEGNDLFREKDYKQALVQYMEGL-NVAAYAASDQ
VALPRELLC

PF00515 // ENSGT00390000018542_0_Domain_0 (130, 164)

KLHV--NRAACYFTMGLYEKALEDSEKALGLDSENIRALFRKARALTELGR
HKEAYACSSRCSLALPHDESVTQLGQELAQ------KLGLRVRKAYKRPQ-ELETFSLLS
N--GTAAGV---------ADQGTSNGLGSIDDIET-GSVPDSRKTDSP--AGRVSSLGDC
YVDLRGSPAPLPST------------------PTMPLFPHVLDLLAPLDSSSRALPGTES
LDDFSDGDVFGPELDTLLDSL-----------SLVQGGLPGGGVPSELPQLIPVFPGGTP
LLPPVVGGSIPVSSPLPPASFGLVVDPAKKLAA-SVLDALEPPGSG-----LDSLD----
---LLPYSETRL--DALDSFGS-SRGSLDKPSSFL----------EDANSQDHRPP----
--------S-----G-TQKPAP------------SPEPSMPNT----ALLIKNPLAATHE
FKQACQLCYPKT-GPRAGDYTYREGLEHKCKRDTLLGRLRSAEDQT-------WKRIRPR
PTKTSFVGSYYLCKDMINKQDCKYGDNCTFAYHQEEIDVWTEERKGTLNRDLLFDPLGGV
KRGSLTIAKLLKEHQGIFTFLCEICFDSKPRIISKGTKDSPSVCSNLAAKHSFYNNKCLV
HIVRSTSLKYSKVRQFQEHFQFDVCRHEVRYGCLREDSCHFAHSFIELKVWLLQQYS-GM
THEDIVQESKKYWQQMEAHTGKASSSL-GAPRTHGPSTFDLQMKFVCGQCWRNGQVVE-P
DKDLKYCSA--KARHCWTKERRV---MSKAKRKWVSVRPLPSIRNFPQQYDVSTR----A
GCRVASGLRIAHSPEERDMWTFMKE------------NKI------LDMQQTY---DMWL
-KKHNPGKPGEGTPVGSREGEKQIQMPTDYADI---MMGYHCWLCGKNSNSKKQWQQHIQ
SEKHKEKVFTSG------AYRFPMGECRRRDRGPPGRGGLQKGKACPDGDKCRCAHGQEE
LNEWLDRREVLKQKLAKARKDMLLCPRDDDFGKYNFLLQEDGNA----PGAAPEAPATAA
GTGD--------------------------------------------------------
----------------------

-------------------------------------------MERQRRKADIEKGLQFI
QSTL-PL--KQEEYEAFLLKLVQNLFAEGNDLFREKDYKQALVQYMEGL-NVADYAASDQ
VALPRELLCKLHV--NRAACYFTMGLYEKALEDSEKALGLDGENIRALFRKARALTELGR
HKEAYACSSRCSLALPHDESVTQLGQELAQ------KLGLRVRKAYKRPQ-ELETFSLLS
N--GTAAGV---------ADQGISNGLGSIDDIET-----------------------DC
YVDLRGSPAPLPST------------------PTMSFFPHVLDLLAPLDSSSRAVPSTES
LDDFSDGDLFGPELDTLLDSL-----------SLVQGGLPGSGVPSELPQLIPVFPGGTP
LLPPVVGGSIPVSSPLPPASFGLVMDPSKKLAA-SVLDALDPPGSA-----LDSLD----
---LLPYSETRL--DALDSFGS-TRGSLDKPSSFM----------EETNSQDHRPP----
--------N-----S-SQKPAS------------SPEPSMPNT----ALLIKNPLAATHE
FKQACQLCYPKT-GPRAGDYTYREGLEHKCKRDILLGRLRSSEDQT-------WKRIRPR
PTKTSFVGSYYLCKDMINKQDCKYGDNCTFAYHQEEIDVWTEERKGTLNRDLLFDPLGGV
KRGSLTIAKLLKEHQGIFTFLCEICFDSKPRIISKGTKDSPAVCSNLAAKHSFYNNKCLV
HIVRSTSLKYCKVRQFQEHFQFDVCRHEVRYGCLREDSCHFAHSFIELKVWLLQQYS-GM
THEDIVQESKKYWQQMEAHAGKASSSL-GAPRTHGPGTFDLQMKFVCGQCWRNGQVVE-P
DKDLKYCSA--KARHCWTKERRVLLVMSKAKRKWVSVRPLPSIRNFPQ

PF00642 // ENSGT00390000018542_0_Domain_4 (949, 974)

QYDLCIHAQNGR
KCQYVGNCSFAHS

ENSGT00390000018542_0_Linker_4_5 (974, 1108)

PEERDMWTFMKE------------NKI------LDMQQTY---DMWL
-KKHNPGKPGEGTPIGSREGEKQIQMPTDYADI---MMGYHCWLCGKNSNSKKQWQQHIQ
SEKHKEKVFTSDSDASGWAYRFPMGEF

PF00642 // ENSGT00390000018542_0_Domain_5 (1108, 1138)

RLCD-------RLQKGKACPDGDKCRCAHGQEE
LNEWLDRREVLKQKLAKARKDMLLCPRDDDFGKYNFLLQEDGNT----AGATPEAPAAAT
IPGE--------------------------------------------------------
----------------------

-------------------------------------------MERQKRKADIEKGLQFI
QSTL-PL--KQEEYEAFLLKLVQNLFAEGNDLFREKDYKQALVQYMEGL-NVADYAASDQ
VALPRELLCK

PF13181 // ENSGT00390000018542_0_Domain_0 (131, 162)

LHV--NRAACYFTMGLYEKALEDSEKALGLDSESIRALFRKARALNELGR
HKEAYECSSRCSLALPHDESVTQLGQELAQ------KLGLRVRKAYKRPQ-ELE--TFSL
LSNGTAAGV---------ADQGTSNGLGSIDDIE-----------------------TDC
YVDPRGSPALLPST------------------PTMPLFPHVLDLLAPLDS-SRTLPSTDS
LDDFSDGDVFGPELDTLLDSL-----------SLVQGGLSGSGVPSELPQLIPVFPGGTP
LLPPVVGGSIPVSSPLPPASFGLVMDPSKKLAA-SVLDALDPPGPT-----LDPLD----
---LLPYSETRL--DALDSFGS-TRGSLDKPDSFMEETNSQ--------D--HRPP----
--------S-----G-AQ------------KPAPSPEPCMPNT----ALLIKNPLAATHE
FKQACQLCYPKT-GPRAGDYTYREGLEHKCKRDILLGRLRSSEDQT-------WKRIRPR
PTKTSFVGSYYLCKDMINKQDCKYGDNCTFAYHQEEIDVWTEERKGTLNRDLLFDPLGGV
KRGSLTIAKLLKEHQGIFTFLCEICFDSKPRIISKGTKDSPSVCSNLAAKHSFYNNKCLV
HIVRSTSLKYSKIRQFQEHFQFDVCRHEVRYGCLREDSCHFAHSFIELKVWLLQQYS-GM
THEDIVQESKKYWQQMEAHAGKASS-SMGAPRTHGPSTFDLQMKFVCGQCWRNGQVVE-P
DKDLKYCSA--KARHCWTKERRVLLVMSKAKRKWVSVRPLPSIRNFPQ

PF00642 // ENSGT00390000018542_0_Domain_4 (949, 974)

QYDLCIHAQNGR
KCQYVGNCSFAHS

ENSGT00390000018542_0_Linker_4_5 (974, 1108)

PEERDMWTFMKE------------NKI------LDMQQTY---DMWL
-KKHNPGKPGEGTPISSREGEKQIQMPTDYADI---MMGYHCWLCGKNSNSKKQWQQHIQ
SEKHKEKVFTSDSDASGWAFRFPMGEF

PF00642 // ENSGT00390000018542_0_Domain_5 (1108, 1138)

RLCD-------RLQKGKACPDGDKCRCAHGQEE
LNEWLDRREVLKQKLAKARKDMLLCPRDDDFGKYNFLLQEDGDL----AGAT--PEAPAA
AATAT-----TGE-----------------------------------------------
----------------------

---------------------------------------NYRCELPCPAEKDLVSFFFPV
RSTL-PL--KQEEYEAFLLKLVQNLFAEGNDLFREKDYKQALVQYMEGL-NVADYAASDQ
VALPRELLCK

PF13181 // ENSGT00390000018542_0_Domain_0 (131, 162)

LHV--NRAACYFTMGLYEKALEDSEKALGLDSESIRALFRKARALNELGR
HKEAYECSSRCSLSLPHDESVTQLGQELAQ------KLGLRVRKAYKRPQ-ELETFSLLS
N--GTAAGV---------TDQCPLSAL-------------------------DLLLFIDC
YVDLQDSPALLPST------------------PTMPLFPHVLDLLAPLDSSSRVLPSTES
LDDFSDGDVFGPELDTLLDSL-----------SLVQGGLPGSGMPSELPQLIPVFPGGTP
LLPPVVGGSIPVSSPLPPASFGLVMDPSKKLAA-SVLDALDPPGPT-----LDPLD----
---LLPYSETRL--DALDSFGS-TRGSLDKPDSFMEETNSQ--------D--HRPP----
--------S-----G-TQKPAP------------SPEPSMPNT----ALLIKNPLAATHE
FKQACQLCYPKT-GPRAGDYTYREGLEHKCKRDILLGRLRSSEDQT-------WKRIRPR
PTKTSFVGSYYLCKDMINKQDCKYGDNCTFAYHQEEIDVWTEERKGTLNRDLLFDPLGGV
KRGSLTIAKLLKEHQGIFTFLCEICFDSKPRIISKGTKDSPSVCSNLAAKHSFYNNKCLV
HIIRSTSLKYSKIRQFQEHFQFDVCRHEVRYGCLREDSCHFAHSFIELKVWLLQQYS-GM
THEDIVQESKKYWQQMEAHAGKASS-SLGAPRTHGPSTFDLQMKFVCGQCWRNGQVVE-P
DKDLKYCSA--KARHCWTKERRVLLVMSKAKRKWVSVRPLPSIRNFPQ

PF00642 // ENSGT00390000018542_0_Domain_4 (949, 974)

QYDLCIHAQNGR
KCQYVGNCSFAHS

ENSGT00390000018542_0_Linker_4_5 (974, 1108)

PEERDMWTFMKD------------NKI------LDMQQTY---DMWL
-KKHNPGKPGEGTPISSREGEKQIQMPTDYADI---MMGYHCWLCGKNSNSKKQWQQHIQ
SEKHKEKVFTSDSDASGWAYRFPMGEF

PF00642 // ENSGT00390000018542_0_Domain_5 (1108, 1138)

RLCD-------RLQKGKACPDGDKCRCAHGQEE
LNEWLDRREVLKQKLAKARKDMLLCPRDDDFGKYNFLLQEDRDT----TGATPEAPAIAA
TTGE--------------------------------------------------------
----------------------

-------------------------------------------MERQKRKADIEKGLQFI
QSTL-PL--KQEEYEAFLLKLVQNLFAEGNDLFREKDYKQALVQYMEGL-NVAEYAASDQ
VALPRELLCKL

PF13181 // ENSGT00390000018542_0_Domain_0 (132, 162)

HV--NRAACYFTMGLYEKALEDSEKALDLDGESIRALFRKARALNELGR
HKEAYECSSRCSLALPHDESVTQLGQELAQ------KLGLRVRKAYKRPQ-ELETFSLLS
N--GTAAGL---------ADQGTCNGLGSIDDIE-----------------------TDC
YVDLRGSPALLPST------------------PMMPLFPHVLDLLAPLDTSSRAAPSMET
MDDFSDGDVFGPELDTLLDSL-----------SLVQGGLPGGGVPSELPQLIPVFPGGTP
LLPPVVGGSIPVSSPLPPASFGLVMDPSKKLAA-SVLDALDPPGPT-----LDPLD----
---LLPYSETRL--DALDSFGS-ARGSLDKPDSFMEDTNSQ--------D--HRPP----
--------G-----S-IQKPVP------------SPEPSMPNT----ALLIKNPLAATHE
FKQACQLCYPKT-GPRAGDYTYREGLEHKCKRDILLGRLRSAEDQT-------WKRIRPR
PTKTSFVGSYYLCKDMINKQDCKYGDNCTFAYHQEEIDVWTEERKGTLNRDLLFDPLGGV
KRGSLTIAKLLKEHQGIFTFLCEICFDSKPRIISKGTKDSPSVCSNLAAKHSFYNNKCLV
HIVRSTSLKYSKIRQFQEHFQFDVCRHEVRYGCLREDSCHFAHSFIELKVWLLQQYS-GM
THEDIVQESKKYWQQMEAHAGKASG-GSGALRTHGPSTFDLQMKFVCGQCWRNGQVVE-P
DKDLKYCSA--KARHCWTKERRVLLVMSKAKRKWVSVRPLPSIRNFPQ

PF00642 // ENSGT00390000018542_0_Domain_4 (949, 974)

QYDLCIHAQNGR
KCQYVGNCSFAHS

ENSGT00390000018542_0_Linker_4_5 (974, 1108)

PEERDMWTFMKE------------NKI------LDMQQTY---DMWL
-KKHNPGKPGEGTPISSREGEKQIQMPTDYADI---MMGYHCWLCGKNSNSKKQWQQHIQ
SEKHKEKVFTSDSDASGWAYRFPMGEF

PF00642 // ENSGT00390000018542_0_Domain_5 (1108, 1138)

RLCD-------RLQKGKACPDGDKCRCAHGQEE
LNEWLDRREVLKQKLAKARKDMLLCPRDDDFGKYNFLLQEDGDT----ASATPXXXXXXX
XXXXXXX---XVGW----------------------------------------------
----------------------

-------------------------------------------MERQRRKADIEKGLQFI
QSTL-PL--KQEEYEAFLLKLVQNLFAEGNDLFREKDYKQALVQYVEGL-NVADYAASDQ
VALPRELL

PF07719 // ENSGT00390000018542_0_Domain_0 (129, 164)

CKLHV--NRAACYFTMGLYEKALEDSEKALGLDGD

ENSGT00390000018542_0_Linker_0_1 (164, 165)

N

PF00515 // ENSGT00390000018542_0_Domain_1 (165, 198)

IRALFRKARALTELGR
HKEAYACSSRCSLALPHDESVTHLGQELAQ------KLGLRVRKAYKRPQ-ELETFSLLS
N--GTAAGV---------ADQGSSNGLGSIDDIET-GSVPDLRGRV------EMGTPGDC
YMDLRGSPAPLPSP------------------PPMPLFPHVLDLLAPLDSSSGALPGTES
LDDFSDGDVFGPELDTLLDSL-----------SLVQGGLPGSGVPSELPQLIPVFPGGTP
LLPPVVGGSIPVSSPLPPASFGLVMDPSKKLAA-SVLDALDPPGSA-----LDSLD----
---LLPYSETRL--DTLDSFGS-TRGSLDKPSSFM----------EEADSQDHRPL----
--------S-----G-TQRPAP------------SPEPSMPNT----ALLIKNPLAATHE
FKQACQLCYPKT-GPRAGDYTYREGLEHKCKRDILLGRLRSSEDQT-------WKRIRPR
PTKTSFVGSYYLCKDMI-KQDCKYGD--CFAYHQEEIDVWTEERKGTLNRDLLFDPLGGV
KRGSLTIAKLLKEHQGIFTFLCEICFDSKPRIISKGTKDCPSVCSNLAAKHSFYNNKCLV
HIVRSTSLKYSKVRQFQEH

PF00642 // ENSGT00390000018542_0_Domain_3 (800, 825)

FQFDVCRHEVRYGCLREDSCHFAHS

ENSGT00390000018542_0_Linker_3_4 (825, 948)

FIELKVWLLQQYS-GM
THEDIVQESKKYWQQVEAHAGKASSSL-GAPRTHGPSTFDLQMKFVCGQCWRNGQVVE-P
DKDLKYCSA--KARHCWTKERRVLLVMSKAKRKWVSVRPLPSIRNFP

PF00642 // ENSGT00390000018542_0_Domain_4 (948, 974)

QQYDLCIHAQNGR
KCQYVGNCSFAHS

ENSGT00390000018542_0_Linker_4_5 (974, 1105)

PEERDMWTFMKE------------NKI------LDMQQTY---DMWL
-KKHNPGKPGEGTPISSREGEKQIQMPTDYADI---MMGYHCWLCGKNSNSKKQWQQHIQ
SEKHKEKVFTSDSDASGWAYRFPM

PF00642 // ENSGT00390000018542_0_Domain_5 (1105, 1138)

GEFRLCE-------RLQKGKACPDGDKCRCAHGQEE
LNEWLDRREVLKQKLAKARKDMLLCPRDDDFGKYNFLLQEDGNA----TGAAPEAPAAAS
VTGE--------------------------------------------------------
----------------------

------------------------------------------------------------
-STL-PL--KQEEYEAFLLKLVQNLFAEGNDLFREKDYKQALVQYMEGL-NVADYAASDQ
VALPRELLCK

PF13181 // ENSGT00390000018542_0_Domain_0 (131, 162)

LHV--NRAACYFTMGLYEKALEDSEKALGLDSESIRALFRKARALNELGR
HKEAYECSSRCSLALPHDESVTQLGQELAQ------KLGLRVRKAYKRPQ-ELE--TFSL
LSNGTAAGV---------ADQGTSNGLGSIDDIE-----------------------TDC
YVDPRGSPALLPST------------------PTMPLFPHVLDLLAPLDS-SRTLPSTES
LDDFSDGDVFGPELDTLLDSL-----------SLVQGGLSGSGVPSELPQLIPVFPGGTP
LLPPVVGGSIPVSSPLPPASFGLVMDPSKKLAA-SVLDALDPPGPT-----LDPLD----
---LLPYSETRL--DALDSFGS-TRGSLDKPDSFMEETSSQ--------D--HRPP----
--------S-----G-AQ------------KPAPSPEPCMPNT----ALLIKNPLAATHE
FKQACQLCYPKT-GPRAGDYTYREGLEHKCKRDILLGRLRSSEDQT-------WKRIRPR
PTKTSFVGSYYLCKDMINKQDCKYGDNCTFAYHQEEIDVWTEERKGTLNRDLLFDPLGGV
KRGSLTIAKLLKEHQGIFTFLCEICFDSKPRIISKGTKDSPSVCSNLAAKHSFYNNKCLV
HIVRSTSLKYSKIRQFQEHFQFDVCRHEVRYGCLREDSCHFAHSFIELKVWLLQQYS-GM
THEDIVQESKKYWQQMEAHTGKASS-SMGTPRTHGPSTFDLQMKFVCGQCWRNGQVVE-P
DKDLKYCSA--KARHCWTKERRVLLVMSKAKRKWVSVRPLPSIRNFPQ

PF00642 // ENSGT00390000018542_0_Domain_4 (949, 974)

QYDLCIHAQNGR
KCQYVGNCSFAHS

ENSGT00390000018542_0_Linker_4_5 (974, 1108)

PEERDMWTFMKE------------NKI------LDMQQTY---DMWL
-KKHNPGKPGEGTPISSREGEKQIQMPTDYADI---MMGYHCWLCGKNSNSKKQWQQHIQ
SEKHKEKVFTSDSDASGWAFRFPMGEF

PF00642 // ENSGT00390000018542_0_Domain_5 (1108, 1138)

RLCD-------RLQKGKACPDGDKCRCAHGQEE
LNEWLDRREVLKQKLAKARKDMLLCPRDDDFGKYNFLLQEDVDP----ASAT--PEAPAA
AAAAI-----TGE-----------------------------------------------
----------------------

-------------------------------------------MERQKRKADIEKGLQFI
QSTL-PL--KQEEYEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---XXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXGLFE-KLEDSEKALGLDGENIRALFRKARALTELGR
HKEAYECSSRCSLALPHDESVTQLGQELAQ------KLGLRVRKAYKRPH-ELETFSLLS
NGM--A---------ASVADQGTSNGLGSIDDIETGSVPDAR-----D--REP-GAPSHC
YMDLRGSPAPLPCT------------------PTMSLFPHIL------DGSSRALPSTES
LDDFSDSDVLGPELDTLLDSL-----------SLVQGGLPGSGLPTELPRLIPVFPGGTP
LLPPVVGGSVPVSSPLPPASFGLVMDSSKKLAA-SVLDTLDPPGSA-----LDSL-----
---LLQYSESRL--DVLDSFGS-SRSSLDKPDSFSVXXXXXXXXXX--------------
-------------------------XXXXXXXXXXPEPSMPNT----ALLIKNPLAATHE
FKQACQLCYPKT-GPRAGDYTFREGLEHKCKRDILLGRLRSADDQT-------WKRILPR
PTKTSFVGSYYLCKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XM
THEDIVQESKKYWQQMEGHAGKASSSL-GAQRPHGPSTFDLQMKFVCGQCWRNGQVVE-P
DKDLKYCSA--KARHCWTKERRVLLVMSKAKRKWVSVRPLPSIRNFP

PF00642 // ENSGT00390000018542_0_Domain_4 (948, 974)

QQYDECIHAQNGR
KCPHFRNCSFAHS

ENSGT00390000018542_0_Linker_4_5 (974, 1112)

PEEXXXXXXXXXXXXXXXXXXXXXXXXXXXX------XXX---XXXX
-XXXXXXXX-XXXXXX-------XXXXXXXXXX---XXXXXXXXXX-X-X--XXX--X--
---XXXXXXXXXXXXXXXXXXXXXXXXXXXX

PF00642 // ENSGT00390000018542_0_Domain_5 (1112, 1138)

XXXXXXXXLQKGKPCPDGDKCRCAHGQEE
LSEWLDRREVLKQKLAKARKDMLLCPRDDDFGKYNFLLQEGGDNTTTEVSTVSATPTTII
TPME--------------------------------------------------------
----------------------

-------------------------------------------MERQKRKADIEKGLQFI
QSTL-PL--KQEEYEAFLLKLVQNLFAEGNDLFREKDYKQALVQYMEGL-NVADYAASDQ
VALPRELLCK

PF13181 // ENSGT00390000018542_0_Domain_0 (131, 162)

LHV--NRAACYFTMGLYEKALEDSEKALGLDSESIRALFRKARALNELGR
HKEAYECSSRCSLALPHDESVTQLGQELAQ------KLGLRVRKAYKRPQ-ELETFSLLS
N--GTAAGV---------ADQVG--------------------------------LGLNC
YVDPRASPALLPST------------------PTMPLFPHVLDLLAPLDS-SRTLPSTDS
LDDFSDGDVFGPELDTLLDSL-----------SLVQGGLSGSGVPSELPQLIPVFPGGTP
LLPPVVGGSIPVSSPLPPASFGLVMDPSKKLAA-SVLDALDPPGPT-----LDPLD----
---LLPYSETRL--DALDSFGS-TRGSLDKPDSFMEETNSQ--------D--HRPP----
--------S-----G-AQKPAPSVMPTMASFLLSQPEPCMPNT----ALLIKNPLAATHE
FKQACQLCYPKT-GPRAGDYTYREGLEHKCKRDILLGRLRSSEDQT-------WKRIRPR
PTKTSFVGSYYLCKDMINKQDCKYGDNCTFAYHQEEIDVWTEERKGTLNRDLLFDPLGGV
KRGSLTIAKLLKEHQGIFTFLCEICFDSKPRIISKGTKDSPSVCSNLAAKHSFYNNKCLV
HIVRSTSLKYSKIRQFQEHFQFDVCRHEVRYGCLREDSCHFAHSFIELKVWLLQQYS-GM
THEDIVQESKKYWQQMEAHAGKASS-SMGAPRTHGPSTFDLQMKFVCGQCWRNGQVVE-P
DKDLKYCSA--KARHCWTKERRVLLVMSKAKRKWVSVRPLPSIRNFPQ

PF00642 // ENSGT00390000018542_0_Domain_4 (949, 974)

QYDLCIHAQNGR
KCQYVGNCSFAHS

ENSGT00390000018542_0_Linker_4_5 (974, 1108)

PEERDMWTFMKE------------NKI------LDMQQTY---DMWL
-KKHNPGKPGEGTPISSREGEKQIQMPTDYADI---MMGYHCWLCGKNSNSKKQWQQHIQ
SEKHKEKVFTSDSDASGWAFRFPMGEF

PF00642 // ENSGT00390000018542_0_Domain_5 (1108, 1138)

RLCD-------RLQKGKACPDGDKCRCAHGQEE
LNEWLDRREVLKQKLAKARKDMLLCPRDDDFGKYNFLLQEDGDP----AGATPEAPTAAA
AATTTGE-----------------------------------------------------
----------------------

-------------------------------------------MERQKRKADIEKGLQFI
QSTL-PL--KQEEYEAFLLKLVQNLFAEGNDLFREKDYKQALVQYMEGL-NVADYAASDQ
VALPRELLCKL

PF13181 // ENSGT00390000018542_0_Domain_0 (132, 162)

HV--NRAACYFTMGLYEKALEDSEKALGLDSESIRALFRKARALNELGR
HKEAYECSSRCSLALPHDESVTQLGQELAQ------KLGLRVRKAYKRPQ-ELETFSLLS
N--GTMAGV---------ADQGTSNGLGSIDDIE-----------------------TDC
CVDLRGSPALLPST------------------PTMPLFPHVLDLLAPLDG-SRVLPSTES
LDDFSDGDVFGPELDSLLDSL-----------SLVQGGLPGSGVPSELPQLIPVFPGGTP
LLPPVVGGSIPVSSPLPPASFGLVMDPSKKLAA-SVLDALDPPGPT-----LDPLD----
---LLPYSETRL--DALDSFGS-ARGSLDKSDSFIEESSSQ--------D--HRPP----
--------S-----S-AQKPAP------------SPEPSMPNT----ALLIKNPLAATHE
FKQACQLCYPKT-GPRAGDYTYREGLEHRCKRDTLLGRLRSSEDPS-------WKRIRPR
PTKTSFVGSYYLCKDMMNKQDCKYGDNCTFAYHQEEIDVWTEERKGTLNRDLLFDPLGGV
KRGSLTIAKLLKEHQGIFTFLCEICFDSKPRIISKGTKDSPSVCSNLAAKHSFDNNKCLV
HIVRSTSLKYSKIRQFQEHFQFDVCRHEVRYGCLREDSCHFAHSFIELKVWLLQQYS-GM
THEDIVQESKKYWQQMEAHAGKASS-SLNAPRTHGPSTFDLQMKFVCGQCWRNGQVVE-P
DKDLKYCSA--KARHCWTKERRVLLVMSKAKRKWVSVRPLPSIRNFPQ

PF00642 // ENSGT00390000018542_0_Domain_4 (949, 974)

QYDLCIHAQNGR
KCQYVGNCSFAHS

ENSGT00390000018542_0_Linker_4_5 (974, 1108)

PEERDMWTFMKE------------NKI------LDMQQTY---DMWL
-KKHNPGKPGEGTPISSREGEKQIQMPTDYADI---MMGYHCWLCGKNSNSKKQWQQHIQ
SEKHKEKVFTSDSDTSGWAFRFPMGEF

PF00642 // ENSGT00390000018542_0_Domain_5 (1108, 1138)

RLCD-------RLQKGKACPDGDKCRCAHGQEE
LNEWLDRREVLKQKLAKARKDMLLCPRDDDFGKYNFLLQEDGDP----AGAS--PEAPAA
TTAATTSTTTSTGE----------------------------------------------
----------------------

-------------------------------------------MERQKRKADIEKGLQFI
QSTL-PL--KQEEYEAFLLKLVQNLLAEGNDLFREKDYKQALVQYMEGL-NVADYAASDQ
VALPRELLCKLHV--NRAACYFTMGLYEKALEDSEKALGLDGESIRALFRKARALNELGR
HKEAYECSSRCSLALPHDESVTQLGQELAQ------KLGLRVRKAYKRPQ-ELE--TFSL
LSNGTAAGM---------SDQGTSNGLGSIDDIE-----------------------TDC
YVDLRGSPALLPST------------------PTMPLFPHVLDLLAPLDSSSRALPSAES
LDDFSDGDVFGPELDSLLDSL-----------SLVQGGLPGSGVPSELPQLIPVFPGGTP
LLPPVVGSSIPVSSPLPPASFGLVMDPSKKLAA-SVLDALDPPGPT-----LDPLD----
---LLPYAETRL--DALDSFGS-TRGSLDKPDSFMEENNSQ--------D--HRPP----
--------S-----G-TQ------------KPAPSPEPSMPNT----ALLIKNPLAATHE
FKQACQLCYPKT-GPRAGDYTYREGLEHKCKRDILLGRLRSSEDQT-------WKRIRPR
PTKTSFVGSYYLCKDMINKQDCKYGDNCTFAYHQEEIDVWTEERKGTLNRDLLFDPLGGV
KRGSLTIAKLLKEHQGIFTFLCEICFDSKPRIISKGTKDTPSVCSNLAAKHSFYNNKCLV
HIVRSTSLKYSKIRQFQEHFQFDVCRHEVRYGCLREDSCHFAHSFIELKVWLLQQYS-GM
THEDIVQESKKYWQQMEAHAGKASS-SLGAPRTHGPSTFDLQMKFVCGQCWRNGQVVE-P
DKDLKYCSA--KARHCWTKERRVLLVMSKAKRKWVSVRPLPSIRNFPQ

PF00642 // ENSGT00390000018542_0_Domain_4 (949, 974)

QYDLCIHAQNGR
KCQYVGNCSFAHS

ENSGT00390000018542_0_Linker_4_5 (974, 1108)

PEERDMWTFMKE------------NKI------LDMQQTY---DMWL
-KKHNPGKPGEGTPVSSREGEKQIQMPTDYADI---MMGYHCWLCGKNSNSKKQWQQHIQ
SEKHKEKVFTSDSDASGWAYRFPMGEF

PF00642 // ENSGT00390000018542_0_Domain_5 (1108, 1138)

RLCD-------RLQKGKACPDGDKCRCAHGQEE
LNEWLDRREVLKQKLAKARKDMLLCPRDDDFGKYNFLLQEDGDT----AGAT--PEAPVA
AATTGE------------------------------------------------------
----------------------

-------------------------------------------MERQRRKADIEKGLQFI
QSTL-PL--KQEEYEAFLLKLVQNLFAEGNDLFREKDYKQALVQYMEGL-NVADYAASDQ
VALPRELLC

PF00515 // ENSGT00390000018542_0_Domain_0 (130, 164)

KLHV--NRAACYFTMGLYEKALEDSEKALGLDSENIRALFRKARALTELGR
HKEAYACSSRCSLALPHDESVTQLGQELAQ------KLGLRVRKAYKRPQ-ELETFSLLS
N--GTAAGV---------ADQGTSNGLGSIDDIET-----------------------DC
YVDLRGSPAPLPST------------------PTMPLFPHVLDLLAPLDSSSRALPGTES
LDDFSDGDVFGPELDTLLDSL-----------SLVQGGLPGGGVPSELPQLIPVFPGGTP
LLPPVVGGSIPVSSPLPPASFGLVVDPSKKLAA-SVLDALEPPGSG-----LDSLD----
---LLPYSETRL--DALDSFGS-SRGSLDKPSSFL----------EDTNSQDHRPS----
--------S-----G-TQKPAP------------SPEPSMPNT----ALLIKNPLAATHE
FKQACQLCYPKT-GPRAGDYTYREGLEHKCKRDMLLGRLRSAEDQT-------WKRIRPR
PTKTSFVGSYYLCKDMINKQDCKYGDNCTFAYHQEEIDVWTEERKGTLNRDLLFDPLGGV
KRGSLTIAKLLKEHQGIFTFLCEICFDSKPRIISKGTKDSPSVCSNLAAKHSFYNNKCLV
HIVRSTSLKYSKVRQFQEHFQFDVCRHEVRYGCLREDSCHFAHSFIELKVWLLQQYS-GM
THEDIVQESKKYWQQMEAHTGKASSSL-GAPRTHGPSTFDLQMKFVCGQCWRNGQVVE-P
DKDLKYCSA--KARHCWTKERRVLLVMSKAKRKWVSVRPLPSIRNFPQQYDLCIHAQNGR
KCQYVGNCSFAHSPEERDMWTFMKE------------NKI------LDMQQTY---DMWL
-KKHNPGKPGEGTPVGSREGEKQIQMPTDYADI---MMGYHCWLCGKNSNSKKQWQQHIQ
SEKHKEKVFTSDSDASGWAYRFPMGEF

PF00642 // ENSGT00390000018542_0_Domain_5 (1108, 1138)

RLCD-------RLQKGKACPDGDKCRCAHGQEE
LNEWLDRREVLKQKLAKARKDMLLCPRDDDFGKYNFLLQEDGNA----PGAALEAPATAA
GTGD--------------------------------------------------------
----------------------

-------------------------------------------MERQKRKADIEKGLQFI
QSTL-PL--KQEEYEAFLLKLVQNLFAEGNDLFREKDYKQALVQYMEGL-NVADYAASDQ
VALPRELLCK

PF13181 // ENSGT00390000018542_0_Domain_0 (131, 162)

LHV--NRAACYFTMGLYEKALEDSEKALGLDSESIRALFRKARALNELGR
HKEAYECSSRCSLALPHDESVTQLGQELAQ------KLGLRVRKAYKRPQ-ELE--TFSL
LSNGTAAGA---------ADQGTSNGLGSIDDIE-----------------------TDC
YVDPRDSPALLPST------------------PTMPLFPHVLDLLAPLDS-SRTLPSTES
LDDFSDGDVFGPELDTLLDSL-----------SLVQGGLSGSGVPSELPQLIPVFPGGTP
LLPPVVGGSIPVSSPLPPASFGLVMDPSKKLAA-SVLDALDPPGPT-----LDPLD----
---LLPYSETRL--DALDSFGS-ARGSLDKPDSFMEETSLQ--------D--HRPP----
--------S-----G-AQ------------KPAPSPEPCMPNT----ALLIKNPLAATHE
FKQACQLCYPKT------------------------------------------------
--------------DMINKQDCKYGDNCTFAYHQEEIDVWTE------------------
----------------------EICFDSKPRIISKGTKDSPSVCSNLAAKHSFYNNKCLV
HIVRSTSLKYSKIRQFQEHFQFDVCRHEVRYGCLREDSCHFAHSFIELKVWLLQQYS-GM
THEDIVQESKKYWQQMEAHAGKASS-SMGTPRTHGPSTFDLQMKFVCGQCWRNGQVVE-P
DKDLKYCSA--KARHCWTKERRVLLVMSKAKRKWVSVRPLPSIRNFPQ

PF00642 // ENSGT00390000018542_0_Domain_4 (949, 974)

QYDLCIHAQNGR
KCQYVGNCSFAHS

ENSGT00390000018542_0_Linker_4_5 (974, 1108)

PEERDMWTFMKE------------NKI------LDMQQTY---DMWL
-KKHNPGKPGEGTPISSREGEKQIQMPTDYADI---MMGYHCWLCGKNSNSKKQWQQHIQ
SEKHKEKVFTSDSDASGWAFRFPMGEF

PF00642 // ENSGT00390000018542_0_Domain_5 (1108, 1138)

RLCD-------RLKKGKACPDGDKCRCAHGQEE
LNEWLDRREVLKQKLAKARKDMLLCPRDDDFGKYNFLLQEDVDP----ASAT--PEAPAA
AAATT-----GE------------------------------------------------
----------------------

------------------------------------------------------------
RSTL-PL--KQEEYEAFLLKLVQNLFAEGNDLFREKDYKQALVQYMEGL-NVADYAASDQ
VALPRELLCK

PF13181 // ENSGT00390000018542_0_Domain_0 (131, 162)

LHV--NRAACYFTMGLYEKALEDSEKALGLDSESIRALFRKARALNELGR
HKEAYECSSRCSLALPHVSVNLYLCPPLS-----------------NLWQ-ELETFSLLS
N--GTAAGV---------ADQVGSGAPLRL----------------------LPTPSADC
YVDPRGSPAFLPST------------------PTMPLFPHVLDLLAPLDS-SRTLPSTES
LDDFSDGDVFGPELDTLLDSL-----------SLVQGGLSGSGVPSELPQLIPVFPGGTP
LLPPVVGGSIPVSSPLPPASFGLVMDPSKKLAA-SVLDALDPPGPT-----LDPLD----
---LLPYSETRL--DALDSFGS-TRGSLDKPDSFMEETNSQ--------D--HRPP----
--------S-----G-AQKPAP------------SPEPCMPNT----ALLIKNPLAATHE
FKQACQLCYPKT-GPRAGDYTYREGLEHKCKRDILLGRLRSSEDQT-------WKRIRPR
PTKTSFVGSYYLCKDMINKQDCKYGDNCTFAYHQEEIDVWTEERKGTLNRDLLFDPLGGV
KRGSLTIAKLLKEHQGIFTFLCEICFDSKPRIISKGTKDSPSVCSNLAAKHSFYNNKCLV
HIVRSTSLKYSKIRQFQEHFQFDVCRHEVRYGCLREDSCHFAHSFIELKVWLLQQYS-GM
THEDIVQESKKYWQQMEAHAGKASS-SMGAPRTHGPSTFDLQMKFVCGQCWRNGQVVE-P
DKDLKYCSA--KARHCWTKERRVLLVMSKAKRKWVSVRPLPSIRNFPQ

PF00642 // ENSGT00390000018542_0_Domain_4 (949, 974)

QYDLCIHAQNGR
KCQYVGNCSFAHS

ENSGT00390000018542_0_Linker_4_5 (974, 1108)

PEERDMWTFMKE------------NKI------LDMQQTY---DMWL
-KKHNPGKPGEGTPISSREGEKQIQMPTDYRSVSPREMGYHCWLCGKNSNSKKQWQQHIQ
SEKHKEKVFTSDSDTSGWAFRFPMGEF

PF00642 // ENSGT00390000018542_0_Domain_5 (1108, 1138)

RLCD-------RLQKGKACPDGDKCRCAHGQEE
LNEWLDRREVLKQKLAKARKDMLLCPRDDDFGKYNFLLQEDGDP----AGATPEAPAAAA
TATTGE------------------------------------------------------
----------------------

-------------------------------------------MERQKRKADIEKGLQFI
QSTL-PL--KQEEYEAFLLKLVQNLFAEGNDLFREKDYKQALVQYMEGL-NVADYAASDQ
VALPRELLCK

PF13181 // ENSGT00390000018542_0_Domain_0 (131, 162)

LHV--NRAACYFTMGLYEKALEDSEKALGLDSESIRALFRKARALNELGR
HKEAYECSSRCSLALPHDESVTQLGQELAQ------KLGLRVRKAYKRPQ-ELE--TFSL
LSNGTAAGV---------ADQGTSNGLGSIDDIE-----------------------TDC
YVDPRASPALLPST------------------PTMPLFPHVLDLLAPLDS-SRTLPSTDS
LDDFSDGDVFGPELDTLLDSL-----------SLVQGGLSGSGVPSELPQLIPVFPGGTP
LLPPVVGGSIPVSSPLPPASFGLVMDPSKKLAA-SVLDALDPPGPT-----LDPLD----
---LLPYSETRL--DALDSFGS-TRGSLDKPDSFMEETNSQ--------D--HRPP----
--------S-----G-AQ------------KPAPSPEPCMPNT----ALLIKNPLAATHE
FKQACQLCYPKT-GPRAGDYTYREGLEHKCKRDILLGRLRSSEDQT-------WKRIRPR
PTKTSFVGSYYLCKDMINKQDCKYGDNCTFAYHQEEIDVWTEERKGTLNRDLLFDPLGGV
KRGSLTIAKLLKEHQGIFTFLCEICFDSKPRIISKGTKDSPSVCSNLAAKHSFYNNKCLV
HIVRSTSLKYSKIRQFQEHFQFDVCRHEVRYGCLREDSCHFAHSFIELKVWLLQQYS-GM
THEDIVQESKKYWQQMEAHAGKASS-SMGAPRTHGPSTFDLQMKFVCGQCWRNGQVVE-P
DKDLKYCSA--KARHCWTKERRVLLVMSKAKRKWVSVRPLPSIRNFPQ

PF00642 // ENSGT00390000018542_0_Domain_4 (949, 974)

QYDLCIHAQNGR
KCQYVGNCSFAHS

ENSGT00390000018542_0_Linker_4_5 (974, 1108)

PEERDMWTFMKE------------NKI------LDMQQTY---DMWL
-KKHNPGKPGEGTPISSREGEKQIQMPTDYADI---MMGYHCWLCGKNSNSKKQWQQHIQ
SEKHKEKVFTSDSDASGWAFRFPMGEF

PF00642 // ENSGT00390000018542_0_Domain_5 (1108, 1138)

RLCD-------RLQKGKACPDGDKCRCAHGQEE
LNEWLDRREVLKQKLAKARKDMLLCPRDDDFGKYNFLLQEDGDP----AGAT--PEAPAA
AAATT-----TTGE----------------------------------------------
----------------------

------------------------------------------------------------
--------------QAFLLKLVQNLFAEGNDLFREKDHKQALVQYMEGL-NVAEYAASDQ
VDLPRELL

PF07719 // ENSGT00390000018542_0_Domain_0 (129, 164)

CKLHV--NRAACYFTMGLYEKALEDSEKALSLDAE

ENSGT00390000018542_0_Linker_0_1 (164, 165)

N

PF00515 // ENSGT00390000018542_0_Domain_1 (165, 198)

IRALFRKARALNELGR
HKEAYECSSRCSLALPH

ENSGT00390000018542_0_Linker_1_2 (198, 668)

DESVTQLGQELAQ------KLGLRVRKAYKRPQ-ELETFSLLS
N--GTAAGA---------ADQGTIRGSPWP--LEK-GNHGCR--REGI--TTEPPHPTNC
YVDLRGSPALLP-T------------------PTMPLFPHVLD-----------------
------------------------------------------GVPSELPQLIPVFPGG-P
LLPPVVGGSIPVSSPLPPASFGLVMDPSKKLAA-SVLDALDPPGSA-----LDSLD----
---LLPYSETRL--DALDSFGS-TRGSLDKPSAFM----------EDPSSQDHRPP----
--------S-----G-TQKPAP------------SPEPSMPNT----ALLIKNPLAATHE
FKQACQLCYPKT-GPRAGDYTYREGLEHKCKRDLLLGRLRSSEDQT-------WKRIRPR
PTKTSFV

PF00642 // ENSGT00390000018542_0_Domain_2 (668, 694)

GSYYLCKDMINKQDCKYGDNCTFAYH

ENSGT00390000018542_0_Linker_2_3 (694, 800)

QEEIDVWTEERKGTLNRDLLFDPLGGV
KRGSLTIAKLLKEHQGIFTFLCEICFDSKPRIISKGTKDSPSVCSNLAAKHSFYNNKCLV
HIVRSTSLKYSKIRQFQEH

PF00642 // ENSGT00390000018542_0_Domain_3 (800, 825)

FQFDVCRHEVRYGCLREDSCHFAHS

ENSGT00390000018542_0_Linker_3_4 (825, 948)

FIELKVWLLQQYS-GM
THEDIVQESKKYWQQMEAHAGKASSSL-GAPRTHGPSTFDLQMKFVCGQCWRNGQVVE-P
DKDLKYCSA--KARHCWTKERRVLLVMSKAKRKWVSVRPLPSIRNFP

PF00642 // ENSGT00390000018542_0_Domain_4 (948, 974)

QQYDLCIHAQNGR
KCQYVGNCSFAHS

ENSGT00390000018542_0_Linker_4_5 (974, 1105)

PEERDMWTFMKE------------NKI------LDMQQTY---DMWL
-KKHNPGKPGEGTPISSREGEKQIQMPTDYADI---MMGYHCWLCGKNSNSKKQWQQHIQ
SEKHKEKVFTSDSDASGWAYRFPM

PF00642 // ENSGT00390000018542_0_Domain_5 (1105, 1138)

GEFRLCD-------RLQKGKACPDGDKCRCAHGQEE
LNEWLDRREVLKQKLAKARKDMLLCPRDDDFGKYNFLLQEDGT-----AGAAPEAPAAAT
VPGE--------------------------------------------------------
----------------------

-------------------------------------------MERQKRKADIEKGLQFI
QSTL-PL--KQEEYEAFLLKLVQNLFAEGNDLFREKDYKQALVQYMEGL-NVADYAASDQ
VALPRELLCK

PF13181 // ENSGT00390000018542_0_Domain_0 (131, 162)

LHV--NRAACYFTMGLYEKALEDSEKALGLDSESIRALFRKARALNELGR
HKEAYECSSRCSLALPHDESVTQLGQELAQ------KLGLRVRKAYKRPQ-ELETFSLLS
N--GTAAGV---------ADQVG--------------------------------LGLNC
YVDPRASPALLPST------------------PTMPLFPHVLDLLAPLDS-SRTLPSTDS
LDDFSDGDVFGPELDTLLDSL-----------SLVQGGLSGSGVPSELPQLIPVFPGGTP
LLPPVVGGSIPVSSPLPPASFGLVMDPSKKLAA-SVLDALDPPGPT-----LDPLD----
---LLPYSETRL--DALDSFGS-TRGSLDKPDSFMEETNSQ--------D--HRPP----
--------S-----G-AQKPAPSVMPTMASFLLSQPEPCMPNT----ALLIKNPLAATHE
FKQACQLCYPKT-GPRAGDYTYREGLEHKCKRDILLGRLRSSEDQT-------WKRIRPR
PTKTSFVGSYYLCKDMINKQDCKYGDNCTFAYHQEEIDVWTEERKGTLNRDLLFDPLGGV
KRGSLTIAKLLKEHQGIFTFLCEICFDSKPRIISKGTKDSPSVCSNLAAKHSFYNNKCLV
HIVRSTSLKYSKIRQFQEHFQFDVCRHEVRYGCLREDSCHFAHSFIELKVWLLQQYS-GM
THEDIVQESKKYWQQMEAHAGKASS-SMGAPRTHGPSTFDLQMKFVCGQCWRNGQVVE-P
DKDLKYCSA--KARHCWTKERRVLLVMSKAKRKWVSVRPLPSIRNFPQ

PF00642 // ENSGT00390000018542_0_Domain_4 (949, 974)

QYDLCIHAQNGR
KCQYVGNCSFAHS

ENSGT00390000018542_0_Linker_4_5 (974, 1108)

PEERDMWTFMKE------------NKI------LDMQQTY---DMWL
-KKHNPGKPGEGTPISSREGEKQIQMPTDYADI---MMGYHCWLCGKNSNSKKQWQQHIQ
SEKHKEKVFTSDSDASGWAFRFPMGEF

PF00642 // ENSGT00390000018542_0_Domain_5 (1108, 1138)

RLCD-------RLQKGKACPDGDKCRCAHGQEE
LNEWLDRREVLKQKLAKARKDMLLCPRDDDFGKYNFLLQEDRDP----AGATPEAPAAAA
AATTTGE-----------------------------------------------------
----------------------

-------------------------------------------MERQKRKADIEKGLQFI
HLHNNPV--RRWSYLRFAEARLVNKANPATTVFRKNSASLIRATDFCGAGAASQSPHFPG
ISLPRKLLCPLSISFQSAACSSRQGLYEKALEDSEKALGLDGENIRALFRKARALNELGR
HKEAYECSSRCSLALPHDESVTQLGQELAQ------KLGLRVRKAYKRPQ-ELETFSLLS
N--GTAAGV---------ADQGTSNGLGSIDDIET-----------------------DC
FMDLRASPAPLHSA------------------PMMPLFPHVLDLLAPLDSGSRALPGPES
LDDFSDGDVFGPELDTLLDSL-----------SLVQGGLPGSGMPSEVPQLIPVFPGGTP
LLPPVVGGSIPVSSPLPPASFGLVMDPSKKLAT-SMLDALDPPGSA-----LDSLD----
---LLPYSETRL--DALDSFGS-TRGTLDKPDSFSM---------EETNAQDHRAP----
--------S-----S-AQKPAP------------SPEPSMPNT----ALLVKNPLAATHE
FKQACQLCYPKT-GPRAGDYTYREGLEHKCKRDILLGRLRSAEDQT-------WKRIRPR
PTKTSFVGSYYLCKDMINKQDCKYGDNCTFAYHQEEIAVWTEERKGTLNRDLLFDPLGGV
KRGSLTIAKLLKEHQGIFTFLCEICFDSKPRIISKGTKDSPSVCSNLAAKHSFYNNKCLV
HIVRSTSLKYSKIRQFQEHFQFDVCRHEVRYGCLREDSCHFAHSFIELKVWLLQQYS-GM
THEDIVQESKKYWQQMEAHAGKVGSSA-GAPRTHAPSTFDLQMKFVCGQCWRNGQVVE-P
DKDLKYCSA--KARHCWTKERRVLLVMSKAKRKWVSVRPLPSIRNFPQQYDLCIHAQNGR
KCQYVGNCSFAHSPEERDMWTFMKE------------NKI------LDMQQTY---DMWL
-KKHNPGKPGEGTPIGSREGEKQIQMPTDYADI---MMGYHCWLCGKNSNSKKQWQQHIQ
SEKHKEKVFTSDSDASGWAYRFPMGEF

PF00642 // ENSGT00390000018542_0_Domain_5 (1108, 1138)

RLCD-------RLQKGKACPDGDKCRCAHGQEE
LNEWLDRREVLKQKLAKARKDMLLCSRDDDFGKYNFLLQEVGDATGDAAGAAPEAPAAAA
AAAGD-------------------------------------------------------
----------------------

--------------------------------------SPQRLMERQKRKADIEKGLQFI
QSTL-PL--KQEEYEAFLLKLVQNLFAEGNDLFREKDHKQALVQYMEGL-NVADYAASDQ
VALPRELL

PF00515 // ENSGT00390000018542_0_Domain_0 (129, 164)

CKLHV--NRAACYFTMGLYEKALEDSEKALGLDSE

ENSGT00390000018542_0_Linker_0_1 (164, 165)

N

PF00515 // ENSGT00390000018542_0_Domain_1 (165, 198)

IRALFRKARALNELGR
HKEAYECSSRCSLALPH

ENSGT00390000018542_0_Linker_1_2 (198, 668)

DESVTQLGQELAQ------KLGLRVRKAYKRPQ-HVQGASLFE
AQQKYPPYCTPPRHPAPLCPSARVRTVGPWDTSSLHQAGP-----SAT--AEPIAPSTDC
YVDLRGSPAPLPST------------------PTMPLFPHVLDLLAPLDSGSRVFPSTES
LDDFSDGDVFGPELDTLLDSL--------------------------------------P
LLPPVVGGSVPVSSPLPPASFGLVMDSSKKLAA-SMLDALDPPGST-----LDSLD----
---LLPYSETRL--DALDSFGS-ARSSLDKPDSFSVECSHIQSLGVPLGRWSRSCL----
--------SGGGWVAWDGFCELETLPKMADLLLSQPEPSMPNT----ALLIKNPLAATHE
FKQACQLCYPKT-GPRAGDYTYREGLEHKCKRDILLGRLRSTEDQT-------WKRIRPR
PTKTSFV

PF00642 // ENSGT00390000018542_0_Domain_2 (668, 694)

GSYYLCKDMINKQDCKYGDNCTFAYH

ENSGT00390000018542_0_Linker_2_3 (694, 800)

QEEIDVWTEERKGTLNRDLLFDPLGGI
KRGSLTIAKLLKEHQGIFTFLCEICFDSKPRIISKGTKDSPSVCSNLAAKHSFHNNKCLV
HIVRSTSLKYSKIRQFQEH

PF00642 // ENSGT00390000018542_0_Domain_3 (800, 825)

FQFDVCRHEVRYGCLREDSCHFAHSFIELKVWLLQQYS-GM
THEDIVQESKKYWQQMEAHTGCLETKRTQ----TKPGWIRFASLFVRAQCSRQTFFTRMF
DRNVQYGTGHHPILVSWPRRQLFMQAISFPRPCWESVRETASCKNQVGTRKSSVRARGP-
----V----IDLMFVTRTTWCYSGPEPRRQAHASLEERGLHGVTPHLQLQGDLGRLCLVM
EQAHHGGRL-EGGGL--------AKGGEQAPTVLYPQMGYHCWLCGKNSNSKKQWQQHIQ
SEKHKEKVFTSDSDASAWAYRFPM

PF00642 // ENSGT00390000018542_0_Domain_5 (1105, 1138)

GEFRLCDR--------CSGKPCPDGDKCRCAHGQEE
LNEWLDRREVLKQKLAKARKDMLLCPRDDDFGKYNFLLQEGG------------------
------------------------------------------------------------
----------------------

--------------------------------------TAAAVMERQKRKEEIEKGLQFI
QSTL-PL--IQEDYEAFLLKLVRNLLAEGNDLFREKDFKLALVQYVEGL-NVAEYAASDE
VTIPVDLLCN

PF00515 // ENSGT00390000018542_0_Domain_0 (131, 160)

LYV--NRAACYFAMGLYEKALEDSEKALGFDAENIRALFRKARCLNELGR
HKEAYECNSRCLLSLPHDESVAQLGQDLAQ------TLGLKVRKAYKRPQ-ELETFSLLS
NGLS--S---------NLPNQVVSFSCFSVDPVCSFRQKPLLEGVIIPT-NVLPKSLDVT
SFCIPLTPS------------------TAALQITLTIGYGPSTLPFS--KAAPV-PASES
VDDFAEGGVLGDELDSILDSLADGSQQYP-LKSLVQGALPA-SMPSEMPRLIPVFPGGTP
LLPPVVAANIPVSTPLPPASFGLMMEATKQLSSSSVLDAFEPPETSTQET----------
--------------------------------------------RQPTNVQKAPPM----
-------------IN-HSGPGHTTVPKVVELLMSQPESMMPNT----ALLVKNPLASTHV
FRQACHLCYPKT-GPKAGDYTYREGLDHKCKKDILLGRRRNIEDKT-------WKRIRPR
PTKTNFVGSYYLCKDMLNKQDCKYGDNCTFAYHQEEIDVWTEERKGTLNRDLLFDPLGGV
KRGSLTIAKILKEHQGVFTFLCEICFDSKPRIISKGTKDSPAVCSNLAAQHSFYNNKCLV
HIVRSTSLKYSKIRQFQEHFQFDVCRHEVRYGCLREDSCHFAHSFIELKIWLLQQYS-GM
THEDIVQESKKYWQQMEAHTNKA------SARGSTSNTFDLQMKFVCGQCWRNGQVVE-P
DKDLKYCSA--KARHCWTKERRVLLVMSKAKRKWVSVRPLPSIRNFPQQYDLCIHAQNGR
KCQYVGNCSFAHSPEEREMWTFMKE------------NKI------LDMQQTY---DMWL
-KKHNPGKPGEGTTLTSREAEKQIQMPTDYAD----MMGYHCWLCGKNSNSKKQWQQHIQ
SEKHKEKVFTSDNDSSCWNYRFPMGEFRLCDRY-----RFQKTKSCPEGEKCCFAHGQDE
LTEWLDRREVMKHKLAKARKDMLLCPRDDDFGKYNFLLRENI------------------
------------------------------------------------------------
----------------------

-------------------------------------------MERQKRKADIEKGLQFI
QSTL-PL--KQEEYEAFLLKLVQNLFAEGNDLFREKDYKQALVQYMEGL-NVADYAASDQ
VALPRELLCK

PF13181 // ENSGT00390000018542_0_Domain_0 (131, 162)

LHV--NRAACYFTMGLYEKALEDSEKALGLDSESIRALFRKARALNELGR
HKEAYECSSRCSLALPHDESVTQLGQELAQ------KLGLRVRKAYKRPQ-ELE--TFSL
LSNGTAAGA---------ADQGTSNGLGSIDDIE-----------------------TDC
YVDPRGSPALLPST------------------PTMPLFPHVLDLLAPLDS-SRTLPSTES
LDDFSDGDVFGPELDTLLDSL-----------SLVQGGLSGSGVPSELPQLIPVFPGGTP
LLPPVVGGSIPVSSPLPPASFGLVMDPSKKLAA-SVLDALDPPGPT-----LDPLD----
---LLPYSETRL--DALDSFGS-TRGSLDKPDSFMEETSSQ--------D--HRPP----
--------S-----G-AQ------------KPAPSPEPCMPNT----ALLIKNPLAATHE
FKQACQLCYPKT-GPRAGDYTYREGLEHKCKRDILLGRLRSSEDQT-------WKRIRPR
PTKTSFVGSYYLCKDMINKQDCKYGDNCTFAYHQEEIDVWTEERKGTLNRDLLFDPLGGV
KRGSLTIAKLLKEHQGIFTFLCEICFDSKPRIISKGTKDSPSVCSNLAAKHSFYNNKCLV
HIVRSTSLKYSKIRQFQEHFQFDVCRHEVRYGCLREDSCHFAHSFIELKVWLLQQYS-GM
THEDIVQESKKYWQQMEAHTGKASS-SVGTSRTHGPSTFDLQMKFVCGQCWRNGQVVE-P
DKDLKYCSA--KARHCWTKERRVLLVMSKAKRKWVSVRPLPSIRNFPQ

PF00642 // ENSGT00390000018542_0_Domain_4 (949, 974)

QYDLCIHAQNGR
KCQYVGNCSFAHS

ENSGT00390000018542_0_Linker_4_5 (974, 1108)

PEERDMWTFMKE------------NKI------LDMQQTY---DMWL
-KKHNPGKPGEGTPISSREGEKQIQMPTDYADI---MMGYHCWLCGKNSNSKKQWQQHIQ
SEKHKEKVFTSDSDASGWAFRFPMGEF

PF00642 // ENSGT00390000018542_0_Domain_5 (1108, 1138)

RLCD-------RLQKGKACPDGDKCRCAHGQEE
LNEWLDRREVLKQKLAKARKDMLLCPRDDDFGKYNFLLQEDVDP----AIAT--PEAPAA
AAATT------GE-----------------------------------------------
----------------------

-------------------------------------------MERQKRKADIEKGLQFI
QSTL-PL--KQEEYEAFLLKLVQNLFAEGNDLFREKDYKQALVQYMEGL-NVADYAASDQ
VALPRELLCK

PF13181 // ENSGT00390000018542_0_Domain_0 (131, 162)

LHV--NRAACYFTMGLYEKALEDSEKALGLDSESIRALFRKARALNELGR
HKEAYECSSRCSLALPHDESVTQLGQELAQ------KLGLRVRKAYKRPQ-ELETFSLLS
N--GTAAGV---------ADQQCSPSS-------------------------LAHPTADC
YVDPRASPALLPST------------------PTMPLFPHVLDLLAPLDS-SRTLPSTDS
LDDFSDGDVFGPELDTLLDSL-----------SLVQGGLSGSGVPSELPQLIPVFPGGTP
LLPPVVGGSIPVSSPLPPASFGLVMDPSKKLAA-SVLDALDPPGPT-----LDPLD----
---LLPYSETRL--DALDSFGS-TRGSLDKPDSFMEETNSQ--------D--HRPP----
--------S-----G-AQKPAPSVMPTMASFLLSQPEPCMPNT----ALLIKNPLAATHE
FKQACQLCYPKT-GPRAGDYTYREGLEHKCKRDILLGRLRSSEDQT-------WKRIRPR
PTKTSFVGSYYLCKDMINKQDCKYGDNCTFAYHQEEIDVWTEERKGTLNRDLLFDPLGGV
KRGSLTIAKLLKEHQGIFTFLCEICFDSKPRIISKGTKDSPSVCSNLAAKHSFYNNKCLV
HIVRSTSLKYSKIRQFQEHFQFDVCRHEVRYGCLREDSCHFAHSFIELKVWLLQQYS-GM
THEDIVQESKKYWQQMEAHAGKASS-SMGAPRTHGPSTFDLQMKFVCGQCWRNGQVVE-P
DKDLKYCSA--KARHCWTKERRVLLVMSKAKRKWVSVRPLPSIRNFPQ

PF00642 // ENSGT00390000018542_0_Domain_4 (949, 974)

QYDLCIHAQNGR
KCQYVGNCSFAHS

ENSGT00390000018542_0_Linker_4_5 (974, 1108)

PEERDMWTFMKE------------NKI------LDMQQTY---DMWL
-KKHNPGKPGEGTPISSREGEKQIQMPTDYADI---MMGYHCWLCGKNSNSKKQWQQHIQ
SEKHKEKVFTSDSDASGWAFRFPMGEF

PF00642 // ENSGT00390000018542_0_Domain_5 (1108, 1138)

RLCD-------RLQKGKACPDGDKCRCAHGQEE
LNEWLDRREVLKQKLAKARKDMLLCPRDDDFGKYNFLLQEDGDP----AGATPEAPAAAA
AATTTGE-----------------------------------------------------
----------------------

-------------------------------------------MERQKRKADIEKGLQFI
QSTL-PL--KQEEYEAFLLKLVQNLFAEGNDLFREKDYKQALVQYMEGL-NVADYAASDQ
VALPRELLCKLHV--NRAACYFTMGLYEKALEDSEKALGLDGESIRALFRKARALNELGR
HKEAYECSSRCSLALPHDENVTQLGQELAQ------KLGLRVRKAYKRPQ-ELETFSLLS
N--GAPAGL---------TDQGTSNGLGSIDDIE-----------------------TDC
YVDLRGSPALLPST------------------PTMPLFPHVLDLLAPLDGSSRTLPGTEG
LDDFSDGDVFGPELDTLLDSL-----------SLVQGGLPGSGMPSELPQLIPVFPGGTP
LLPPVVGGSIPVSSPLPPASFGLVMDPSRKLAA-SVLDALDSPGPT-----LDPLD----
---LLPYSEARL--GALDSFGS-ARGSLDKPDSFLEETSSQ--------D--HRPP----
--------S-----S-TQKPAP------------SPEPSMPNT----TLLIKNPLAATHE
FKQACQLCYPKT-GPRAGDYTYREGLEHKCRRDVLLGRLRSSENQI-------WKRIRPR
PTKTSFVGSYYLCKDMINKQDCKYGDNCTFAYHQEEIDVWTEERKGTLNRDLLFDPLGGV
KRGSLTIAKLLKEHQGIFTFLCEICFDSKPRIISKGTKDSPSVCSNLAAKHSFYNNKCLV
HIVRSTSLKYSKIRQFQEHFQFDVCRHEVRYGCLREDSCHFAHSFIELKVWLLQQYS-GM
THEDIVQESKKYWQQMEAHAGKASS-GLGAPRTHGPSTFDLQMKFVCGQCWRNGQVVE-P
DKDLKYCSA--KARHCWTKERRVLLVMSKAKRKWVSVRPLPSIRNFPQ

PF00642 // ENSGT00390000018542_0_Domain_4 (949, 974)

QYDLCIHAQNGR
KCQYVGNCSFAHS

ENSGT00390000018542_0_Linker_4_5 (974, 1108)

PEERDMWTFMKE------------NKI------LDMQQTY---DMWL
-KKHNPGKPGEGTPISSREGEKQIQMPTDYADI---MMGYHCWLCGKNSNSKKQWQQHIQ
SEKHKEKVFTSDSDASGWAYRFPMGEF

PF00642 // ENSGT00390000018542_0_Domain_5 (1108, 1138)

RLCD-------RLQKGKACPDGDKCRCAHGQEE
LNEWLDRREVLKQKLAKARKDMLLCPRDDDFGKYNFLLQEDGDT----TGATPDAPVAAT
ATAATT---TTGE-----------------------------------------------
----------------------

-------------------------------------------MERQKRKADIEKGLQFI
QSTL-PL--KQEEYEAFLLKLVQNLFAEGNDLFREKDYKQALVQYVEGL-NVADYAASDQ
VALPRELLCK

PF13181 // ENSGT00390000018542_0_Domain_0 (131, 162)

LYV--NRAACYFTMGLYEKALEDSEKALGLDGESIRALYRKARALNELGR
HKEAYECSSRCSLALPHDENVTQLGQELAQ------KLGLRVRKAYKRPQ-ELETFSLLS
N--GTPTGV---------TDQGTSNGLGSIDDIE-----------------------TDC
YVDLRGSPALLPST------------------PTMPLFPHVLDLLAPLDGSSRILPSAEG
LDDFSDGDVFGPELDTLLDSL-----------SLVQGGLSGSGMPSELPQLIPVFPGGTP
LLPPVVGGSVPVSSPLPPASFGLVMDPSRKLAA-SVLDALDSPGPT-----LDPLD----
---LLPYSEARL--DALDSFGS-ARGSLDKPDAFIEETSSQ--------D--HRPP----
--------S-----S-TQKPAP------------SPEPSMPNT----ALLIKNPLAATHE
FKQACQLCYPKT-GPRAGDYTYREGLEHKCKRDVLLGRLRSSEDQI-------WKRIRPR
PTKTSFVGSYYLCKDMINKQDCKYGDSCTFAYHQEEIDVWTEERKGTLNRDLLFDPLGGV
KRGSLTIAKLLKEHQGIFTFLCEICFDSKPRIISKGTKDSPSVCSNLAAKHSFYNNKCLV
HIVRSTSLKYSKIRQFQEHFQFDVCRHEVRYGCLREDSCHFAHSFIELKVWLLQQYS-GM
THEDIVQESKKYWQQMEAHAGKASS-SLGAPRTHGPSTFDLQMKFVCGQCWRNGQVVE-P
DKDLKYCSA--KARHCWTKERRVLLVMSKAKRKWVSVRPLPSIRNFPQ

PF00642 // ENSGT00390000018542_0_Domain_4 (949, 974)

QYDLCIHAQNGR
KCQYVGNCSFAHS

ENSGT00390000018542_0_Linker_4_5 (974, 1108)

PEERDMWTFMKE------------NKI------LDMQQTY---DMWL
-KKHNPGKPGEGTPISSREGEKQIQMPTDYADI---MMGYHCWLCGKNSNSKKQWQQHIQ
SEKHKEKVFTSDSDASGWAYRFPMGEF

PF00642 // ENSGT00390000018542_0_Domain_5 (1108, 1138)

RLCD-------RLQKGKACPDGDKCHCAHGQEE
LNEWLDRREVLRQRLAKARKDMLLCPRDDDFGKYNFLLQEDGDT----TAATPEAPVAAT
AAAATT---TTGE-----------------------------------------------
----------------------

-------------------------------------------MERQKRKADIEKGLQFI
QSTL-PL--KQEEYEAFLLKLVQNLFAEGNDLFREKDYKQALVQYMEGL-NVADYAASDQ
VALPRELLCK

PF13181 // ENSGT00390000018542_0_Domain_0 (131, 162)

LHV--NRAACYFTMGLYEKALEDSEKALGLDSESIRALFRKARALNELGR
HKEAYECSSRCSLALPHDESVTQLGQELAQ------KLGLRVRKAYKRPQ-VGGLGTLGG
SVWTATVAL---------SPQGTSNGLGSIDDIE-----------------------TDC
YVDPRGSPALLPST------------------PTMPLFPHVLDLLAPLDS-SRTLPSTDS
LDDFSDGDVFGPELDTLLDSL-----------SLVQGGLSGSGVPSELPQLIPVFPGGTP
LLPPVVGGSIPVSSPLPPASFGLVMDPSKKLAA-SVLDALDPPGPT-----LDPLD----
---LLPYSETRL--DALDSFGS-TRGSLDKPDSFMGKAMGG--------H--HPVP----
--------T-----M-AS------------FLLSQPEPCMPNT----ALLIKNPLAATHE
FKQACQLCYPKT-GPRAGDYTYREGLEHKCKRDILLGRLRSSEDQT-------WKRIRPR
PTKTSFVGSYYLCKDMINKQDCKYGDNCTFAYHQEEIDVWTEERKGTLNRDLLFDPLGGV
KRGSLTIAKLLKEHQGIFTFLCEICFDSKPRIISKGTKDSPSVCSNLAAKHSFYNNKCLV
HIVRSTSLKYSKIRQFQEHFQFDVCRHEVRYGCLREDSCHFAHSFIELKVWLLQQYS-GM
THEDIVQESKKYWQQMEAHAGKASS-SMGAPRTHGPSTFDLQMKFVCGQCWRNGQVVE-P
DKDLKYCSA--KARHCWTKERRVLLVMSKAKRKWVSVRPLPSIRNFPQ

PF00642 // ENSGT00390000018542_0_Domain_4 (949, 974)

QYDLCIHAQNGR
KCQYVGNCSFAHS

ENSGT00390000018542_0_Linker_4_5 (974, 1108)

PEERDMWTFMKE------------NKI------LDMQQTY---DMWL
-KKHNPGKPGEGTPISSREGEKQIQMPTDYADI---MMGYHCWLCGKNSNSKKQWQQHIQ
SEKHKEKVFTSDSDTSGWAFRFPMGEF

PF00642 // ENSGT00390000018542_0_Domain_5 (1108, 1138)

RLCD-------RLQKGKACPDGDKCRCAHGQEE
LNEWLDRREVLKQKLAKARKDMLLCPRDDDFGKYNFLLQEDGDL----AGAT--PEGPAA
AATATT------GE----------------------------------------------
----------------------

-----------------------------------------RLMERQKRKADIEKGLQFI
QSTL-PL--KQEEYEAFLLKLVQNLLAEGNDLFREKDYKQALVQYVEGL-NVADYAASDQ
VALPRELLC

PF00515 // ENSGT00390000018542_0_Domain_0 (130, 161)

KLHV--NRAACYFTMGLYEKALEDSEKALCLDGESIRALFRKARALNELGR
HKEAYECSSRCSLALPHDESVTQLGQELAQ------KLGLRVRKAYKRPQ-ELETFSLPG
QGRKVLYNL---------RIVDPEGGLSTPS---A-QTFSSLQS-------FMALLFSHS
TRHPTNSPALLPST------------------PTMPLFPHVLDLLAPLDSSCRAPPSTEN
LDDFSDGDVFGPELDSLLDSL--------------------------------------P
LLPPVVGGSIPVSSPLPPASFGLVMDPSKKLAA-SVLDALDPPGPT-----LDPLD----
---LLPYSETRL--DALDSFGS-ARGSLDKPDSFIVWLTGLVGSH-GAMMQGHGLG----
--------TMSQAKE-TFLGAVGSLKRSKTADVLGPEPCMPNT----ALLIKNPLAATHE
FKQACQLCYPKT-GPRAGDYTYREGLEHKCKRDILLGRLRSSEDQT-------WKRIRPR
PTKTSFVGSYYLCKDMINKQDCKYGDNCTFAYHQEEIDVWTEERKGTLNRDLLFDPLGGV
KRGSLTIAKLLKEHQGIFTFLCEICFDSKPRIISKGTKDSPSVCSNLAAKHSFYNNKCLV
HIVRSTALKYSKIRQFQEHFQFDVCRHEVRYGCLREDSCHFAHSFIELKVWLLQQYS-GM
THEDIVQESKKYWQQMEAHAGKASS-SLGTPRAHGPSTFDLQMKFVCGQCWRNGQVVE-P
DKDLKYCSA--KARHCWTKERRVLLVMSKAKRKWVSVRPLPSIRNFPQQYDLCIHAQNGR
KCQYVGNCSFAHSPEERDMWTFMKE------------NKI------LDMQQTY---DMWL
-KKHNPGKPGEGTPISSREGEKQIQMPTDYADI---MMGYHCWLCGKNSNSKKQWQQHIQ
SEKHKEKVFTSDSDASGWAYRFPMGEF

PF00642 // ENSGT00390000018542_0_Domain_5 (1108, 1138)

RLCD-------RLQKGKACPDGDKCRCAHGQEE
LNEWLDRREVLKQKLAKARKDMLLCPRDDDFGKYNFLLQEDG------------------
------------------------------------------------------------
----------------------

-------------------------------------------MERQRRKADIEKGLQFI
QSTL-PL--KQEEYEAFLLKLVQNLFAEGNDLFREKDYKQALVQYMEGL-NVADYAASDQ
VALPQELLC

PF00515 // ENSGT00390000018542_0_Domain_0 (130, 163)

KLHV--NRAACYFTMGLYEKALEDSEKALGLDGENIRALFRKARALNELGR
HKEAYECSSRCSLALPHDESVTQLGQELAQ------KLGLRVRKAYKRPQ-ELETFSLLS
N--GTAAGV---------ADQGTSNGLGSIDDIET-----------------------EC
YVDLRGSPAPLPST------------------PTMPLFPHVLDLLAPLDSSSRALPGTES
LDDFSDGDVLGPELDTLLDSL-----------SLVQGGLPGSGVPSELPQLIPVFPGGTP
LLPPVVGGSIPVSSPLPPASFGLVMDPSKKLAA-SVLDALDPPGSA-----LDSLD----
---LLPYSETRL--DALDSFGSSSRGSLDKPNSFM----------EETNSQDHRPS----
--------S-----G-TQKPAS------------SPEPSMPNT----ALLIKNPLAATHE
FKQACQLCYPKT-GPRAGDYTYREGLEHKCKRDILLGRLRSSEDQT-------WKRIRPR
PTKTSFVGSYYLCKDMINKQDCKYGDNCTFAYHQEEIDVWTEERKGTLNRDLLFDPLGGV
KRGSLTIAKLLKEHQGIFTFLCEICFDSKPRIISKGTKDSPSVCSNLAAKHSFYNNKCLV
HIVRSTSLKYSKIRQFQEHFQFDVCRHEVRYGCLREDSCHFAHSFIELKVWLLQQYS-GM
THEDIVQESKKYWQQMEAHAGKASSSL-GAPRTHGPSTFDLQMKFVCGQCWRNGQVVE-P
DKDLKYCSA--KARHCWTKERRVLLVMSKAKRKWVSVRPLPSIRNFPQQYDLCIHAQNGR
KCQYVGNCSFAHSPEERDMWTFMKE------------NKI------LDMQQTY---DMWL
-KKHNPGKPGEGTPISSREGEKQIQMPTDYADI---MMGYHCWLCGKNSNSKKQWQQHIQ
SEKHKEKVFTSDSDASGWAYRFPMGEF

PF00642 // ENSGT00390000018542_0_Domain_5 (1108, 1138)

RLCD-------RLQKGKACPDGDKCRCAHGQEE
LNEWLDRREVLKQKLAKARKDMLLCPRDDDFGKYNFLLQEDGNT----AGAAPEAPAAAT
VSGE--------------------------------------------------------
----------------------

-------------------------------------------MERQKRKADIEKGLQFI
QSTL-PL--KQEEYEAFLLKLVQNLFAEGNDLFREKDYKQALVQYMEGL-NVADYAASDQ
VALPRELLCKLHV--NRAACYFTMGLYEKALEDSEKALGLDGESIRALFRKARALNELGR
HKEAYECSSRCSLALPHDENVTQLGQELAQ------KLGLRVRKAYKRPQ-ELETFSLLS
N--GAPAGL---------TDQGTSNGLGSIDDIE-----------------------TDC
YVDLRVSPALLPST------------------PTMPLFPHVLDLLAPLDGSSRTLPAAEG
LDDFSDGDVFGPELDTLLDSL-----------SLVQGGLPGSGMPSELPQLIPVFPGGTP
LLPPVVGGSIPVSSPLPPASFGLVMDPSRKLAA-SVLDALESPGPT-----LDPLD----
---LLPYPEARL--GALDSFGS-ARGSLDKPDSFLEETSSQ--------D--HRPP----
--------S-----S-TQKPAL------------SPEPSMPNT----TLLIKNPLAATHE
FKQACQLCYPKT-GPRAGDYTYREGLEHKCRRDVLLGRLRSSENQI-------WKRIRPR
PTKTSFVGSYYLCKDMINKQDCKYGDNCTFAYHQEEIDVWTEERKGTLNRDLLFDPLGGV
KRGSLTIAKLLKEHQGIFTFLCEICFDSKPRIISKGTKDSPSVCSNLAAKHSFYNNKCLV
HIVRSTSLKYSKIRQFQEHFQFDVCRHEVRYGCLREDSCHFAHSFIELKVWLLQQYS-GM
THEDIVQESKKYWQQMEAHAGKASS-GLGTPRTHGPSTFDLQMKFVCGQCWRNGQVVE-P
DKDLKYCSA--KARHCWTKERRVLLVMSKAKRKWVSVRPLPSIRNFPQ

PF00642 // ENSGT00390000018542_0_Domain_4 (949, 974)

QYDLCIHAQNGR
KCQYVGNCSFAHS

ENSGT00390000018542_0_Linker_4_5 (974, 1108)

PEERDMWTFMKE------------NKI------LDMQQTY---DMWL
-KKHNPGKPGEGTPISSREGEKQIQMPTDYADI---MMGYHCWLCGKNSNSKKQWQQHIQ
SEKHKEKVFTSDSDASGWAYRFPMGEF

PF00642 // ENSGT00390000018542_0_Domain_5 (1108, 1138)

RLCD-------RLQKGKACPDGDKCRCAHGQEE
LNEWLDRREVLKQKLAKARKDMLLCPRDDDFGKYNFLLQEDGDT----TGATPDAPIAAT
ATAATT---TAGE-----------------------------------------------
----------------------

-------------------------------------------MERQKRKADIEKGLQFI
QSTL-PL--KQEEYEAFLLKLVQNLFAEGNDLFREKDYKQALVQYMEGL-NVADYAASDQ
VALPRELLCK

PF13181 // ENSGT00390000018542_0_Domain_0 (131, 162)

LHV--NRAACYFTMGLYEKALEDSEKALGLDSESIRALFRKARALNELGR
HKEAYECSSRCSLALPHDESVTQLGQELAQ------KLGLRVRKAYKRPQ-ELETFSLLS
N--GTAAGV---------ADQQCSPSS-------------------------LAHPTADC
YVDPRASPALLPST------------------PTMPLFPHVLDLLAPLDS-SRTLPSTDS
LDDFSDGDVFGPELDTLLDSL-----------SLVQGGLSGSGVPSELPQLIPVFPGGTP
LLPPVVGGSIPVSSPLPPASFGLVMDPSKKLAA-SVLDALDPPGPT-----LDPLD----
---LLPYSETRL--DALDSFGS-TRGSLDKPDSFMGKAIGGAPLA-GRVE--ALPP----
--------S-----G-AQ---AGPMPTMASFLLSQPEPCMPNT----ALLIKNPLAATHE
FKQACQLCYPKT-GPRAGDYTYREGLEHKCKRDILLGRLRSSEDQT-------WKRIRPR
PTKTSFVGSYYLCKDMINKQDCKYGDNCTFAYHQEEIDVWTEERKGTLNRDLLFDPLGGV
KRGSLTIAKLLKEHQGIFTFLCEICFDSKPRIISKGTKDSPSVCSNLAAKHSFYNNKCLV
HIVRSTSLKYSKIRQFQEHFQFDVCRHEVRYGCLREDSCHFAHSFIELKVWLLQQYS-GM
THEDIVQESKKYWQQMEAHAGKASS-SMGAPRTHGPSTFDLQMKFVCGQCWRNGQVVE-P
DKDLKYCSA--KARHCWTKERRVLLVMSKAKRKWVSVRPLPSIRNFPQ

PF00642 // ENSGT00390000018542_0_Domain_4 (949, 974)

QYDLCIHAQNGR
KCQYVGNCSFAHS

ENSGT00390000018542_0_Linker_4_5 (974, 1108)

PEERDMWTFMKE------------NKI------LDMQQTY---DMWL
-KKHNPGKPGEGTPISSREGEKQIQMPTDYADI---MMGYHCWLCGKNSNSKKQWQQHIQ
SEKHKEKVFTSDSDASGWAFRFPMGEF

PF00642 // ENSGT00390000018542_0_Domain_5 (1108, 1138)

RLCD-------RLQKGKACPDGDKCRCAHGQEE
LNEWLDRREVLKQKLAKARKDMLLCPRDDDFGKYNFLLQEDGDP----AGATPEAPAAAA
PATTTGE-----------------------------------------------------
----------------------

--------------------------------------SAEAIMERQKRKEEIEKGLQFI
QSTL-PL--SQEDYEAFLQKLVRNLFSEGNDLFREKDFKLALVQYVEGL-NVADYAASDE
VIIPVELLCKLHV--NRAACYFAMGVYEKALEDSEKALVLEKENIRALFRKARSLNELGR
HKEAYECNSRCLLSLPHDESVTQLGQELAQ------KLGLRVRKAYKRPQNIFECLC--G
TGVM--V---------GLNTIIKK----------------IISSIIIHTSVKLPIYSLPR
AQNLQCIPAPLATSIPVSEGTALSSSDMDTKGLSTS-LPSATLLPSP--DCMSL-PVPES
VEDFTDGEVIGEELDSLLDSLADGSQYSLLPKSLVQGTIPT-NLPTEMPQLIPVFPGGTP
LLPPVSSDFPP-PRPWTAH------------------------AGGSQS-ILCSVSTSKI
EMCVWDFSSSAQKKLVLRNCGT-LLGARNHL-----------------------------
-------LCL------------RHVCNFINHYFGLA-LAVRFT----RGMLKNPLASTHI
FKQACHLCYPKT-GPKAGDYTYREGLEHKCKRDILLGRLRNSEDKT-------WKRIRPR
PTKTNFVGSYYLCKDMINKQDCKYGDNCTFAYHQEEIDVWTEERKGTLNRDLLFDPLGGI
KRGNLTIAKLLKEHQGIFTFLCEICFDSKPRIISKGTKDSPAVCSNLAAKHSFYDNKCLV
HIVRSTSLKYSKIRQFQEHFQFDVCRHEVRYGCLREDSCHFAHSFIELKVWLLQQYS-GM
THEDIVQESKKYWQLIQLSKCSKQD----KGQQRLDSHFDLQMKFVCGQCWRNGQVVE-P
DKDLKYCSA--KARHWQCKGQAVLRVMSKAKRKWVSVRPLPSIRNFPQQYDLCIHAQNGR
KCQYVGNCSFAHSPEERDMWTFMKE------------NKI------LDMQQTY---DMWL
-KKHNPGKPGEGTPLTSREGEKQIQMPTDYADI---MMGYHCWLCGKNSNSKKQWQQHIQ
SEKHKEKVFTSDNDSSCWNYRFPMGEF

PF00642 // ENSGT00390000018542_0_Domain_5 (1108, 1138)

RLCER-------LQKTKACPEGEKCRYAHGQDE
LTEWLDRREVLKQKLAKARKDMLLCPKDDDFGKYNFLLRDGV------------------
------------------------------------------------------------
----------------------

-------------------------------------------MERQKRKDEIEKGLQFI
QSTL-PL--RQEDYEAFLQKLVRNLFAEGNDLYRERDFKQALVQYVEGL-NVADYAASDE
VALPPDLLC

PF00515 // ENSGT00390000018542_0_Domain_0 (130, 164)

KLHV--NRAACYFTMGLYEKALEDSEKALELDQDNIRALFRKARALNELGR
HKEAYECSSHCSLTLPHVERVTQLGQELAQ------KLGLRVRKAYKRPQQELETFSLLS
PSPP--R---------GLSQLSPPLS------------------------------SSPT
PFFV-----PLTCSL-----------------YSSP-LPYVLSL-SR--RTGGGPRSEPR
AQRLSDGDVWVPELDSLLDSP----------YALVQGSLSS-SLPSEMPQLIPVFPGGTP
LLPPVVPGSIPVSTPLPPASFGLVMDPTKKLAS-AVLDAFDAPGPP-----LDSLD--PL
D--LLPYTEARM--DALDSFGP-VRASLDTLDSFSGGLQTDSHPVPQ-------------
---DHGPREE-------------------GGWAPQPEPLCLSA----PLWPEETLTTTHA
RDQP-RGCRGRT-GR------------RGSSPSILFQRERRSPGKPFFFLDRIGSRLRVC
PLGERKPVSLLPFADMINKQDCKYGDNCTFAYHQEEIDVWTEERKGTLNRDLLFDPLGGV
RRGTLTIDKVLKEHQGIFTFLCEICFDSKPRIISKGTKDSPAVCSNLAAKHSFYDNKCLV
HIVRSTTLKYSKIRQFQEHFQFDVCRHEVRYGCLREDSCHFAHSFIELKVWLLQQYSGGM
THEDIVLESKKFWQQMESHTGKAANSM-VRGRAAGLG----------GTKWESCGPAA-S
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

-------------------------------------------MERQKRKADIEKGLQFI
QSTL-PL--KQEEYEAFLFKLVQNLFAEGNDLFREKDYKQALVQYMEGL-NVADYAASDQ
VALPGELLCKL

PF13181 // ENSGT00390000018542_0_Domain_0 (132, 162)

HV--NRAACYFTMGLYEKALEDSEKALGLDSESIRALFRKARALNELGR
HKEAYECSSRCSLALPHDEGVTQLGQELAQ------KLGLRVRKAYKRPQ-ELETFSLLS
N--GTAAGM---------ADQGTSNGLGSIDDIE-----------------------TDC
YVDLRGSPALLPST------------------TLMPLFPHVLDLLAPLDTSSRAAPSTES
MDDFSDGDVFGPELDTLLDSL-----------SLVQGGLPGGGVPSELPQLIPVFPGGTP
LLPPVVGGSIPVSSPLPPASFGLVMDPSKKLAA-SVLDALDPPGPM-----LDPLD----
---LLPYSETRL--DALDSFGS-ARGSLDKPDSFMEDTNPQ--------E--HRPA----
--------S-----S-IQKAAL------------SPEPSMPNT----ALLIKNPLAATHE
FKQACQLCYPKT-GPRAGDYTYREGLEHKCKRDILLGRLRSAEDQT-------WKRIRPR
PTKTSFVGSYYLCKDMINKQDCKYGDNCTFAYHQEEIDVWTEERKGTLNRDLLFDPLGGI
KRGSLTIAKLLKEHQGIFTFLCEICFDSKPRIISKGTKDSPSVCSNLAAKHSFYNNKCLV
HIVRSTSLKYSKIRQFQEHFQFDVCRHEVRYGCLREDSCHFAHSFIELKVWLLQQYS-GM
THEDIVQESKKYWQQMEAHAGKASS-SSSAPRTHGPSTFDLQMKFVCGQCWRNGQVVE-P
DKDLKYCSA--KARHCWTKERRVLLVMSKAKRKWVSVRPLPSIRNFPQ

PF00642 // ENSGT00390000018542_0_Domain_4 (949, 974)

QYDLCIHAQNGR
KCQYVGNCSFAHSPEERDMWTFMKE------------NKI------LDMQQTY---DMWL
-KKHNPGKPGEGTPISSREGEKQIQMPTDYADI---MMGYHCWLCGKNSNSKKQWQQHIQ
SEKHKEKVFTSDSDASGWAYRFPMGEFRLCD-------RIQKGKTCPDGDKCRCAHGQEE
LNEWLDRREVLKQKLAKARKDMLLCPRDDDFGKYNFLLQEDGDT----ASATPEVPAAAV
ATAAATAAATTTAE----------------------------------------------
----------------------

--------------------------------------LLVVLMARQKRKEDIEKGLQFI
QSTI-PFHGSHADYEHFLQQLVRNLFAEGNDLYRDGDAKLALGQYTEGL-TVAEYAVSEE
LTIPEELLSKLCV--NRSCCYFTMGLYEKSLEDSESALNHDKENMRALYRKAKALDQLGR
HQEAYGCISDKLLALVQDESVTELAQELVQ------KLGLKQRKAYKRPQVLLHCYLGET
AAVQKKS----------IN-----QNLQVVKSMHYIAGRQ--------------LWVTTH
FMCLL--PTDASSNSLGSLDDIDVGSDLHIEGLKAAG--------SP--PSTGFPSAAGS
LNDFADCDIIGDELDSFLDAG------------------------------IPVYTTGST
LLSSLGNNVLPAPSPLPPASFGLLDSQKL-------TRHCDKPGYNS-------------
--NLLRLVEPRL--DALDSFEG-IREPMDCLDTFPNGNEETDSLILHFEEPKHLLS---P
SA----------KTSQKHKPGVNNIN----HI--KMDAAVLHARALLPTPLANSLAHTYD
FKQACHQCFVKT-GPKALDYAHREKLEHKCKRNILLARQKTSENKT-------WLRIRPR
PPK--VT

PF00642 // ENSGT00390000018542_0_Domain_2 (668, 694)

GPYVLCKDIQTRQDCKYREDCTFAYY

ENSGT00390000018542_0_Linker_2_3 (694, 800)

QEEIDVWNEERKLTLRRDQLFLLPSGV
KAGTVT--WLLQEHKGIFIFLCQACFDSKPRVISKKSQENPSVCTK---QHYFLDNKCLV
HVYNCDTIKYSKIRPLQSH

PF00642 // ENSGT00390000018542_0_Domain_3 (800, 825)

YHMDLCRHEMQYGCLQEDTCSFAHS

ENSGT00390000018542_0_Linker_3_4 (825, 948)

HVELNVWILQRQS-GT
TQEEIVQESEQDWKVPETKMPGCR---ILYHPQALPKCLDMKMKFVCSQCLSTGQHIE-S
DRDGKYCAA--KARHSWTKEKRVLLVMSKAKKKWVSARPLPSIRQFP

PF00642 // ENSGT00390000018542_0_Domain_4 (948, 974)

QHYEICIHVQNGK
KCQYSGNCTFAHS

ENSGT00390000018542_0_Linker_4_5 (974, 1105)

TEEKDVWTFMKD------------NKV------LDLQLVF---DLCQ
KNNCPPEKAEKGASGPQKETEKQILMPTDYADL---MAGFHCYLCGKNSNSERQWQKHIR
SEKHKDRVFTTESEDTTWKFRFPA

PF00642 // ENSGT00390000018542_0_Domain_5 (1105, 1138)

GEFKLCDR-------FEETKDCPHESNCQFAHGQEE
LDEWLKRRDVLLQKVSKARKDMLLEPTDSDFGKYTFLLKDVA------------------
------------------------------------------------------------
----------------------

-------------------------------------------MERQKRKADIEKGLQFI
QSTL-PL--KQEEYEAFLLKLVQNLLAEGNDLFREKDYKQALVQYMEGL-NVADYAASDQ
VALPRELLCKLHV--NRAACYFTMGLYEKALEDSEKALGLDGESIRALFRKARALNELGR
HKEAYECSSRCSLALPHDESVTQLGQELAQ------KLGLRVRKAYKRPQ-ELE--TFSL
LSNGTVAGM---------PDQGTSNGLGSIDDIE-----------------------TDC
YVDLRGSPALLPST------------------PTMPLFPHVLDLLAPLDSSSRALPSAES
LDDFSDGDVFGPELDSLLDSL-----------SLVQGGLPGSGVPSELPQLIPVFPGGTP
LLPPVVGGSIPVSSPLPPASFGLVMDPSKKLAA-SVLDALEPPGPT-----LDPLD----
---LLPYAETRL--DALDSFGS-TRGSLDKPDSFMEENNSQ--------D--HRPP----
--------S-----G-TQ------------KPAPSPEPSMPNT----ALLIKNPLAATHE
FKQACQLCYPKT-GPRAGDYTYREGLEHKCKRDILLGRLRSSEDQT-------WKRIRPR
PTKTSFVGSYYLCKDMINKQDCKYGDNCTFAYHQEEIDVWTEERKGTLNRDLLFDPLGGV
KRGSLTIAKLLKEHQGIFTFLCEICFDSKPRIISKGTKDSPSVCSNLAAKHSFYNNKCLV
HIVRSTSLKYSKIRQFQEHFQFDVCRHEVRYGCLREDSCHFAHSFIELKVWLLQQYS-GM
THEDIVQESKKYWQQMEAHAGKASS-SLGAPRTHGPSTFDLQMKFVCGQCWRNGQVVE-P
DKDLKYCSA--KARHCWTKERRVLLVMSKAKRKWVSVRPLPSIRNFPQ

PF00642 // ENSGT00390000018542_0_Domain_4 (949, 974)

QYDLCIHAQNGR
KCQYVGNCSFAHS

ENSGT00390000018542_0_Linker_4_5 (974, 1108)

PEERDMWTFMKE------------NKI------LDMQQTY---DMWL
-KKHNPGKPGEGTPVSSREGEKQIQMPTDYADI---MMGYHCWLCGKNSNSKKQWQQHIQ
SEKHKEKVFTSDSDASGWAYRFPMGEF

PF00642 // ENSGT00390000018542_0_Domain_5 (1108, 1138)

RLCD-------RLQKGKACPDGDKCRCAHGQEE
LNEWLDRREVLKQKLAKARKDMLLCPRDDDFGKYNFLLQEDGDT----AGAT--PETPVA
AATTGE------------------------------------------------------
----------------------

------------------------------------------------------------
--STLPL--KQEEYEAFLLKLVQNLFAEGNDLFREDDHKQALVQYMEGL-NVADYAASDQ
VALPRELLCKLHV--NRAACYFSMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------KLGLRVRKAYKRPQ-ELENFSPLS
N--GAAASV---------THQGTPNGLGPIDDIET-GTGPAPGA------QSPPRALEDC
YVDLRGSPAPLPAT------------------PTLPLFPHVLDLLGPLESGGRALPGSEG
PDDFSDGDLFGPELDTLLDSL-----------SLVQGGLPGSGAPSELPQLIPVFPGGTP
LLPPVVGGSIPVSSPLPPASFGLVMDPSKKLAA-SVLDALDPPGSA-----LDPLD----
---LLPFSEPRL--DALSSLGS-PRGSLDKPDSFSEKTNSQDH----------RPP----
--------ST------TQKP------------AASPEPSMPNT----ALLIKNPLAATHE
FKQACQLCYPKT-GPRAGDYTYREGLEHKCKRDTLLGRLRSAADQT-------WKRIRPR
PTKTSFV

PF00642 // ENSGT00390000018542_0_Domain_2 (668, 694)

GSYYLCKDMINKQDCKYGDNCTFAYH

ENSGT00390000018542_0_Linker_2_3 (694, 800)

QEEIDVWTEERKGTLNRDLLFDPLGGV
QRGSLTIAKLLKEHQGIFTFLCEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXCLV
HIVRSTSLKYSKIRQFQEH

PF00642 // ENSGT00390000018542_0_Domain_3 (800, 825)

FQFDVCRHEVRYGCLREDSCHFAHSFIELKVWLLQQYS-GM
THEDIVQESKKYWQQMEAHAGKGSSGV---------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

--------------------------------------MWRRLMERQKRKEEIEKGLQFI
QSTI-SL--KQEDYEAFLHKLVWNLFAEGNDLFREKDFKQALVQYVEGL-NVADYAASDE
VTLPRELLC

PF00515 // ENSGT00390000018542_0_Domain_0 (130, 164)

KLHV--NRAACYFSMGLYEKALEDSEKALGLDPENIRALFRKASSLNELGR
HKEAYECSKTCSISLPHDESVTQLSRELAQ------KLRLPCRKAYKRPQ-ELETFSLLS
NGTS--A---------PLADQGTSNGLGSIDDIE----------------------T-DC
SMDLRCLTAPTTASIPGCDITLLPD--PEIKGSTTTLFPPTSDLLA----PPDG-AGPEN
MEDFSDGDVFGPELDSLLDSLS-----------LVQGSIPV-TIPSEMPQRIPVFPGGAP
LLPPVVSATIPVSNPLPPASFGLVMDPTKKMTS-SMLEAFDSPASS-----LDTLD--HL
D--LLPYTDAHL--EALDSFGP-VRGSLDTLDSFTVEDTSSQDLRPPSITQKPPPAP---
-------------AS-LSSTSHSPLPKVADML-PQQESALPNT----ALLVKNPLASTHL
FKQACHLCYPKT-GPKAGDYTYREDLEHKCKRDILLGRIRNSEDKT-------WKRIRPR
PTKTSFIGSYYLCKDMLNKQDCKYGDNCTFAYHQEEIDVWTEERKGTLNRDLLFDPLGGV
KRGSLTIAKLLKEHQGIFTFLCEICFDSKPRIISKGTKDSPPVCSNLAAKHSFHDNKCLV
HIVRSTALKYSKIRQFQEHFQFDVCRHEVRYGCLREDSCHFAHSFIELKVWLLQQYS-GM
THEDIVQESKKCWQQMEAHAGKAANSL-ASSRIPPPSTFDLQMKFVCGQCWRNGQVVE-P
DKDLKYCSA--KARHCWTKERRVLLVMSKVKRKWVSVRPLPSIRSFPQQYDLCIHAQNGR
KCQYVGNCSFAHSPEERDMWTFMKE------------NKI------LDMQQTY---DMWL
-KKHNPGKPGEGTQVTPREGEKQIQMPTDYADV---MMGFHCWLCGKNSNSKKQWQQHIQ
SEKHKEKVFTSDSDSTCWTFRFPMGEF

PF00642 // ENSGT00390000018542_0_Domain_5 (1108, 1138)

RLCER-------FQKKKACPDGEKCRCAHGQEE
LTEWLDRREVLKQKLAKARNDMLLCPMDDDFGKYNFLLQDSV------------------
------------------------------------------------------------
----------------------

-------------------------------------------MERQKRKADIEKGLQFI
QSTL-PL--KQEEYEAFLLKLVQNLFAEGNDLFREKDYKQALVQYMEGL-NVADYAASDQ
VALPRELLCK

PF13181 // ENSGT00390000018542_0_Domain_0 (131, 162)

LHV--NRAACYFTMGLYEKALEDSEKALGLDSESIRALFRKARALNELGR
HKEAYECSSRCSLALPHDESVTQLGQELAQ------KLGLRVRKAYKRPQ-ELETFSLLS
N--GTAAGV---------ADQVG--------------------------------LGLNC
YVDPRASPALLPST------------------PTMPLFPHVLDLLAPLDS-SRTLPSTDS
LDDFSDGDVFGPELDTLLDSL-----------SLVQGGLSGSGVPSELPQLIPVFPGGTP
LLPPVVGGSIPVSSPLPPASFGLVMDPSKKLAA-SVLDALDPPGPT-----LDPLD----
---LLPYSETRL--DALDSFGS-TRGSLDKPDSFMEETNSQ--------D--HRPP----
--------S-----G-AQKPAPSVMPTMASFLLSQPEPCMPNT----ALLIKNPLAATHE
FKQACQLCYPKT-GPRAGDYTYREGLEHKCKRDILLGRLRSSEDQT-------WKRIRPR
PTKTSFVGSYYLCKDMINKQDCKYGDNCTFAYHQEEIDVWTEERKGTLNRDLLFDPLGGV
KRGSLTIAKLLKEHQGIFTFLCEICFDSKPRIISKGTKDSPSVCSNLAAKHSFYNNKCLV
HIVRSTSLKYSKIRQFQEHFQFDVCRHEVRYGCLREDSCHFAHSFIELKVWLLQQYS-GM
THEDIVQESKKYWQQMEAHAGKASS-SMGAPRTHGPSTFDLQMKFVCGQCWRNGQVVE-P
DKDLKYCSA--KARHCWTKERRVLLVMSKAKRKWVSVRPLPSIRNFPQ

PF00642 // ENSGT00390000018542_0_Domain_4 (949, 974)

QYDLCIHAQNGR
KCQYVGNCSFAHS

ENSGT00390000018542_0_Linker_4_5 (974, 1108)

PEERDMWTFMKE------------NKI------LDMQQTY---DMWL
-KKHNPGKPGEGTPISSREGEKQIQMPTDYADI---MMGYHCWLCGKNSNSKKQWQQHIQ
SEKHKEKVFTSDSDASGWAFRFPMGEF

PF00642 // ENSGT00390000018542_0_Domain_5 (1108, 1138)

RLCD-------RLQKGKACPDGDKCRCAHGQEE
LNEWLDRREVLKQKLAKARKDMLLCPRDDDFGKYNFLLQEDRDP----AGATPEAPAAAA
AATTTGE-----------------------------------------------------
----------------------

-------------------------------------------MERQKRKADIEKGLQFI
QSTL-PL--KQEEYEAFLLKLVQNLFAEGNDLFREKDYKQALVQYMEGL-NVADYAASDQ
VALPRELLCK

PF13181 // ENSGT00390000018542_0_Domain_0 (131, 162)

LYV--NRAACYFTMGLYEKALEDSEKALGLDSESIRALYRKARALNELGR
HKEAYECSSRCSLALPHDENVTQLGQELAQ------KLGLRVRKAYKRPQ-ELETFSLLS
N--GTPAGM---------TDQGTSNGLGSIDDIE-----------------------TDC
YVDLRGSPALLPST------------------PTMPLFPHVLDLLAPLDGSSRTLPITEG
LDDFSDGDVFGPELDTLLDSL-----------SLVQGGLSGSGVPSELPQLIPVFPGGTP
LLPPVVGGSIPVSSPLPPASFGLVMDPSRKLAA-SVLDALDSPGPT-----LDPLD----
---LLPYSEARL--DALDSFGS-ARGSLDKPDAFIEETSSQ--------D--HRPP----
--------S-----S-TQKPAP------------SPEPSMPNT----ALLIKNPLAATHE
FKQACQLCYPKT-GPRAGDYTYREGLEHKCKRDVLLGRLRSSEDQI-------WKRIRPR
PTKTSFVGSYYLCKDMINKQDCKYGDNCTFAYHQEEIDVWTEERKGTLNRDLLFDPLGGV
KRGSLTIAKLLKEHQGIFTFLCEICFDSKPRIISKGTKDSPSVCSNLAAKHSFYNNKCLV
HIVRSTSLKYSKIRQFQEHFQFDVCRHEVRYGCLREDSCHFAHSFIELKVWLLQQYS-GM
THEDIVQESKKYWQQMEAHAGKASS-SLGAPRTHGPSTFDLQMKFVCGQCWRNGQVVE-P
DKDLKYCSA--KARHCWTKERRVLLVMSKAKRKWVSVRPLPSIRNFPQ

PF00642 // ENSGT00390000018542_0_Domain_4 (949, 974)

QYDLCIHAQNGR
KCQYVGNCSFAHS

ENSGT00390000018542_0_Linker_4_5 (974, 1108)

PEERDMWTFMKE------------NKI------LDMQQTY---DMWL
-KKHNPGKPGEGTPISSREGEKQIQMPTDYADI---MMGYHCWLCGKNSNSKKQWQQHIQ
SEKHKEKVFTSDSDASGWAYRFPMGEF

PF00642 // ENSGT00390000018542_0_Domain_5 (1108, 1138)

RLCD-------RLQKGKACPDGDKCRCAHGQEE
LNEWLDRREVLKQKLAKARKDMLLCPRDDDFGKYNFLLQEDGDT----TAATPEAPIAAT
ATAATT---TTTGE----------------------------------------------
----------------------

-------------------------------------------MERQKRKADIEKGLQFI
QSTL-PL--KQEEYEAFLFKLVQNLFAEGNDLFREKDYKQALVQYMEGL-NVADYAASDQ
VALPGELLCKL

PF13181 // ENSGT00390000018542_0_Domain_0 (132, 162)

HV--NRAACYFTMGLYEKALEDSEKALGLDSESIRALFRKARALNELGR
HKEAYECSSQCSLALPHDEGVTQLGQELAQ------KLGLRVRKAYKRPQ-ELETFSLLS
N--GTAAGM---------ADQGTSNGLGSIDDIE-----------------------TDC
YVDLRGSPALLPST------------------TLMPLFPHVLDLLAPLDTSSRAAPSTES
MDDFSDGDVFGPELDTLLDSL-----------SLVQGGLPGGGVPSELPQLIPVFPGGTP
LLPPVVGGSIPVSSPLPPASFGLVMDPSKKLAA-SVLDALDPPGPM-----LDPLD----
---LLPYSETRL--DALDSFGS-ARGSLDKPDSFVEDTNPQ--------E--HRPA----
--------S-----S-IQKAAL------------SPEPSMPNT----ALLIKNPLAATHE
FKQACQLCYPKT-GPRAGDYTYREGLEHKCKRDILLGRLRSAEDQT-------WKRIRPR
PTKTSFVGSYYLCKDMINKQDCKYGDNCTFAYHQEEIDVWTEERKGTLNRDLLFDPLGGI
KRGSLTIAKLLKEHQGIFTFLCEICFDSKPRIISKGTKDSPSVCSNLAAKHSFYNNKCLV
HIVRSTSLKYSKIRQFQEHFQFDVCRHEVRYGCL----CATLHSFIELKVWLLQQYS-GM
THEDIVQESKKYWQQMEAHAGKASSRGSSAPRTHGPSTFDLQMKFVCGQCWRNGQVVE-P
DKDLKYCSA--KARHCWTKERRVLLVMSKAKRKWVSVRPLPSIRNFPQ

PF00642 // ENSGT00390000018542_0_Domain_4 (949, 974)

QYDLCIHAQNGR
KCQYVGNCSFAHSPEERDMWTFMKE------------NKI------LDMQQTY---DMWL
-KKHNPGKPGEGTPISSREGEKQIQMPTDYADI---MMGYHCWLCGKNSNSKKQWQQHIQ
SEKHKEKVFTSDSDASGWAYRFPMGEFRLCD-------RIQKGKTCPDGDKCRCAHGQEE
LNEWLDRREVLKQKLAKARKDMLLCPRDDDFGKYNFLLQEDGDT----ASATPEVPAAAV
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXAATTTAE

-------------------------------------------MERQKRKADIEKGLQFI
QSTL-PL--KQEEYEAFLLKLVQNLFAEGNDLFREKDYKQALVQYMEGL-NVADYAASDQ
VALPCELLCKLHV--NRAACYFTMGLYEKALEDSEKALGLDGESIRALFRKARALNELGR
HKEAYECSSRCSLALPHDESVTQLGQELAQ------KLGLRVRKAYKRPQ-ELETFSLLS
N--GTAAAM---------ADQGTSNGLGSIDDIE-----------------------TDC
YVDLRGSPALLPST------------------PTMPLFPHVLDLLAPLDSSSRAAPSTES
LDDFSDGDVFGPELDTLLDSL-----------SLVQGGLPGGSVPSELPQLIPVFPGGTP
LLPPVVGGSIPVSSPLPPASFGLVMDPSKKLAA-SVLDALDPPGPT-----LDPLD----
---LLPYSETRL--DALDSFGS-ARGSLDKPDSFLEETSSQ--------E--HRLP----
--------S-----S-TQKPAP------------SPEPSMPNT----ALLIKNPLAATHE
FKQACQLCYPKT-GPRAGDYTYREGLEHKCKRDTLLGRLRSAEDQT-------WKRIRPR
PTKTSFVGSYYLCKDMINKQDCKYGDNCTFAYHQEEIDVWTEERKGTLNRDLLFDPLGGV
KRGSLTIAKLLKEHQGIFTFLCEICFDSKPRIISKGTKDSPAVCSNLAAKHSFYNNKCLV
HIVRSTSLKYSKIRQFQEHFQFDVCRHEVRYGCLREDSCHFAHSFIELKVWLLQQYS-GM
THEDIVQESKKYWQQMEAHAGKASS-GSGAPRTHGPSTFDLQMKFVCGQCWRNGQVVE-P
DKDLKYCSA--KARHCWTKERRVLLVMSKAKRKWVSVRPLPSIRNFPQ

PF00642 // ENSGT00390000018542_0_Domain_4 (949, 974)

QYDLCIHAQNGR
KCQYVGNCSFAHS

ENSGT00390000018542_0_Linker_4_5 (974, 1108)

PEERDMWTFMKE------------NKI------LDMQQTY---DMWL
-KKHNPGKPGEGTPISSREGEKQIQMPTDYADI---MMGYHCWLCGKNSNSKKQWQQHIQ
SEKHKEKVFTSDSDASGWAYRFPMGEF

PF00642 // ENSGT00390000018542_0_Domain_5 (1108, 1138)

RLCD-------RLQKGKACPDGDKCRCAHGQEE
LNEWLDRREVLKQKLAKARKDMLLCPRDDDFGKYNFLLQEDGDT----AGATPEVPAAAT
AATASTAAAAE-------------------------------------------------
----------------------

-------------------------------------------MERQKRKADIEKGLQFI
QSTL-PL--KQEEYEAFLLKLVQNLFAEGNDLFREKDYKQALVQYMEGL-NVADYAASDQ
VALPRELLCKL

PF13181 // ENSGT00390000018542_0_Domain_0 (132, 162)

HV--NRAACYFTMGLYEKALEDSEKALGLDSESIRALFRKARALNELGR
HKEAYECSSRCSLALPHDESVTQLGQELAQ------KLGLRVRKAYKRPQ-ELETFSLLS
N--GTAAAM---------ADQGTSNGLGSIDDIE-----------------------TDC
YVDLRGSPALLPST------------------PTMPLFPHVLDLLAPLDSSSRTAPSTEN
LDDFSDGDVFGPELDTLLDSL-----------SLVQGGLPGGSMPSELPQLIPVFPGGTP
LLPPVVGGSIPVSSPLPPASFGLVMDPSKKLAA-SVLDALDPPGPT-----LDPLD----
---LLPYSETRL--DALDSFGS-ARGSLDKPDSFMEETNSQ--------E--HRPP----
--------S-----S-TQKPAP------------SPEPSMPNT----ALLIKNPLAATHE
FKQACQLCYPKT-GPRAGDYTYREGLEHKCKRDILLGRLRSAEDQT-------WKRIRPR
PTKTSFVGSYYLCKDMINKQDCKYGDNCTFAYHQEEIDVWTEERKGTLNRDLLFDPLGGV
KRGSLTIAKLLKEHQGIFTFLCEICFDSKPRIISKGTKDSPSVCSNLAAKHSFYNNKCLV
HIVRSTSLKYSKIRQFQEHFQFDVCRHEVRYGCLREDSCHFAHSFIELKVWLLQQYS-GM
THEDIVQESKKYWQQMEAHAGKASS-SSGAPRTHGPSTFDLQMKFVCGQCWRNGQVVE-P
DKDLKYCSA--KARHCWTKERRVLLVMSKAKRKWVSVRPLPSIRNFPQ

PF00642 // ENSGT00390000018542_0_Domain_4 (949, 974)

QYDLCIHAQNGR
KCQYVGNCSFAHS

ENSGT00390000018542_0_Linker_4_5 (974, 1108)

PEERDMWTFMKE------------NKI------LDMQQTY---DMWL
-KKHNPGKPGEGTPISSREGEKQIQMPTDYADI---MMGYHCWLCGKNSNSKKQWQQHIQ
SEKHKEKVFTSDSDASGWAYRFPMGEF

PF00642 // ENSGT00390000018542_0_Domain_5 (1108, 1138)

RLCD-------RLQKGKACPDGDKCRCAHGQEE
LSEWLDRREVLKQKLAKARKDMLLCPRDDDFGKYNFLLQEDAEA----ASAAPEVPAAAA
AAATTTTTATTATTTAAE------------------------------------------
----------------------

-------------------------------------------MERQKRKQEIEKGLQFI
QSTL-PL--SQEDYEAFLQKLVRNLFAEGNDLFREKDFKLSLVQYVEGL-NVADYAASDE
VTIPKELL

PF00515 // ENSGT00390000018542_0_Domain_0 (129, 164)

CKLHV--NRAACYFAMGKYEKALEDSEKALGLDKE

ENSGT00390000018542_0_Linker_0_1 (164, 165)

N

PF00515 // ENSGT00390000018542_0_Domain_1 (165, 198)

IRALFRKARSLNELGR
HKEAYECNSRCLLSLPH

ENSGT00390000018542_0_Linker_1_2 (198, 668)

DESVTQLGQELAQ------KLGLRVRKAYKRPQQELETFSLLS
NGTS--I---------NLSNQTTSNGLGSIDDID---TA--------PR-QNSLDKVKDS
GVCRNCWFADLAVRK------ASTRSSGSNVALQPH-TERDGLLPSP--DCVPL-PVPES
VEDFTDGDIIGEELDSLLDSLS-----------LVQGTIPT-NLPTEMPQLIPVFPGGTP
LLPPVVTASIPVSTPLPPASFGLVMDPTKQLSSSSVLDAFEPPPGGSGGSTLDSLD--SL
DLL--PYTDSRL--DALDSFGT-SRGSLDALDSFAIEETSPQELRHPPGSQKPSPV----
-----------------------------------PEPVMPNT----ALLVKNPLASTHV
FKQACHICYPKTAGPKAGDYTYREGLEHKCKRDILLGRLKNSEDKT-------WKRIRPR
PTKTNFV

PF00642 // ENSGT00390000018542_0_Domain_2 (668, 694)

GSYYLCKDMLNKQDCKYGDNCTFAYH

ENSGT00390000018542_0_Linker_2_3 (694, 800)

QEEIDVWTEERKGTLNRDLLFDPLGGI
KQSSLTIAKLLKEHQGIFTFLCEICFDSKPRIISKGTKDTPAVCSNLSAKHSFHDNKCLV
HIVRSTSLKYSKIRQFQEH

PF00642 // ENSGT00390000018542_0_Domain_3 (800, 825)

FQFDVCRHEVRYGCLREDSCHFAHS

ENSGT00390000018542_0_Linker_3_4 (825, 948)

FIELKVWLLQQYS-GM
THEDIVQESKKYWQQMEAHASKPANSM-ASPRAPTSSTFDLQMKFVCGQCWRNGQLVE-P
DKDLKYCSA--KARHCWTKERRVLLVMSKAKKKWVSVRPLPSIRNFP

PF00642 // ENSGT00390000018542_0_Domain_4 (948, 974)

QQYDLCIHAQNGR
KCQYVGNCSFAHS

ENSGT00390000018542_0_Linker_4_5 (974, 1105)

PEERDMWTFMKE------------NKI------LDMQQTY---DMWL
-KKHNPGKPGEGTPLTSREGEKQIQMPTDYADI---MMGYHCWLCGKNSNSKKQWQQHIQ
SEKHKEKVFTSDSDSSCWSYRFPM

PF00642 // ENSGT00390000018542_0_Domain_5 (1105, 1138)

GEFQLCER-------FQKNKACPEGEECRYAHGQDE
LTEWLDRREVLKQKLAKARKDMLLCPRDDDFGKYNFLLRDGVYAARA---SPAYTAAVGL
------------------------------------------------------------
----------------------

-------------------------------------------MERQKRKADIEKGLQFI
QSTL-PL--KQEEYEAFLLKLVQNLFAEGNDLFREKDYKQALVQYMEGL-NVADYAASDQ
VALPRELLCK

PF13181 // ENSGT00390000018542_0_Domain_0 (131, 162)

LYV--NRAACYFTMGLYEKALEDSEKALGLDGESIRALFRKARALNELGR
HKEAYECSSRCSLALPHDENVTQLGQELAQ------KLGLRVRKAYKRPQ-ELETFSLLS
N--GAPAGL---------TDQGTSNGLGSIDDIE-----------------------TDC
YVDLRGSPALLPST------------------PTMPLFPHVLDLLAPLDGSSRPLPSTEG
LDDFSDGDVFGPELDTLLDSL-----------SLVQGGLPGSGMPSELPQLIPVFPGGTP
LLPPVVGGSIPVSSPLPPASFGLVMDPSRKLAA-SVLDALDSPGPT-----LDPLD----
---LLPYSEARL--DALDSFGS-ARGSLDKPDSFLEEASSQ--------D--HRPP----
--------S-----S-TQKPAP------------SPEPSMPNT----ALLIKNPLAATHE
FKQACQLCYPKT-GPRAGDYTYREGLEHKCRRDVLLGRLRSSENQI-------WKRIRPR
PTKTSFVGSYYLCKDMINKQDCKYGDNCTFAYHQEEIDVWTEERKGTLNRDLLFDPLGGV
KRGSLTIAKLLKEHQGIFTFLCEICFDSKPRIISKGTKDSPSVCSNLAAKHSFYNNKCLV
HIVRSTSLKYSKIRQFQEHFQFDVCRHEVRYGCLREDSCHFAHSFIELKVWLLQQYS-GM
THEDIVQESKKYWQQMEAHAGKASS-GLGTPRTHGPSSFDLQMKFVCGQCWRNGQVVE-P
DKDLKYCSA--KARHCWTKERRVLLVMSKAKRKWVSVRPLPSIRNFPQ

PF00642 // ENSGT00390000018542_0_Domain_4 (949, 974)

QYDLCIHAQNGR
KCQYVGNCSFAHS

ENSGT00390000018542_0_Linker_4_5 (974, 1108)

PEERDMWTFMKE------------NKI------LDMQQTY---DMWL
-KKHNPGKPGEGTPISSREGEKQIQMPTDYADI---MMGYHCWLCGKNSNSKKQWQQHIQ
SEKHKEKVFTSDSDASGWAYRFPMGEF

PF00642 // ENSGT00390000018542_0_Domain_5 (1108, 1138)

RLCD-------RLQKGKVCPDGDKCRCAHGQEE
LNEWLDRREVLKQKLAKARKDMLLCPRDDDFGKYNFLLQEDGDT----TGATPEATVAAT
ATAATT---TTGE-----------------------------------------------
----------------------

-------------------------------------------MERQKRKADIEKGLQFI
QSTL-PL--KQEEYEAFLLKLVQNLFAEGNDLFREKDYKQALVQYMEGL-NVADYAASDQ
VALPRELLCK

PF13181 // ENSGT00390000018542_0_Domain_0 (131, 162)

LHV--NRAACYFTMGLYEKALEDSEKALGLDSESIRALFRKARALNELGR
HKEAYECSSRCSPRLP---TVTQLGQELAQ------KLGLRVRKAYKRPQ-GLG------
--------A---------GIGGTSNGLGSIDDIE-----------------------TDC
YMDPRGSPALLPST------------------PTMPLFPHVLDLLAPLDS-SRTLPSTES
LDDFSDGDVFGPELDTLLDSL-----------SLVQGGLSGSGVPSELPQLIPVFPGGTP
LLPPVVGGSIPVSSPLPPASFGLVMDPSKKLAA-SVLDALDPPGPT-----LDPLD----
---LLPYSETRL--DALDSFGS-TRGSLDKPDSFMEETSSQ--------D--HRPP----
--------S-----G-AQ------------KPAPSPEPCMPNT----ALLIKNPLAATHE
FKQACQLCYPKT-GPRAGDYTYREGLEHKCKRDILLGRLRSSEDQT-------WKRIRPR
PTKTSFVGSYYLCKDMINKQDCKYGDNCTFAYHQEEIDVWTEERKGTLNRDLLFDPLGGV
KRGSLTIAKLLKEHQGIFTFLCEICFDSKPRIISKGTKDSPSVCSNLAAKHSFYNNKCLV
HIVRSTSLKYSKIRQFQEHFQFDVCRHEVRYGCLREDSCHFAHSFIELKVWLLQQYS-GM
THEDIVQESKKYWQQMEAHAGKASS-SVGTPRTHGPSTFDLQMKFVCGQCWRNGQVVE-P
DKDLKYCSA--KARHCWTKERRVLLVMSKAKRKWVSVRPLPSIRNFPQ

PF00642 // ENSGT00390000018542_0_Domain_4 (949, 974)

QYDLCIHAQNGR
KCQYVGNCSFAHS

ENSGT00390000018542_0_Linker_4_5 (974, 1108)

PEERDMWTFMKE------------NKI------LDMQQTY---DMWL
-KKHNPGKPGEGTPISSREGEKQIQMPTDYADI---MMGYHCWLCGKNSNSKKQWQQHIQ
SEKHKEKVFTSDSDASGWAFRFPMGEF

PF00642 // ENSGT00390000018542_0_Domain_5 (1108, 1138)

RLCD-------RLQKGKACPDGDKCRCAHGQEE
LSEWLDRREVLKQKLAKARKDMLLCPRDDDFGKYNFLLQEDVDP----ASAT--PEASAA
AAAAAA----TTGE----------------------------------------------
----------------------

-------------------------------------------MERQRRKADIEKGLQFI
QSTLP-L--KXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---XXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXGLYEKALEDSEKALSLDGENIRALFRKARALNELGR
HKEAYECSSRCSLALPHDESVTQLGQELAQ------KLGLRVRKAYKRPQ-ELETFSLLS
N--GTAAGM---------ADQGTSNGLGSIDDIET-GSVHDVRGQV------EIGALGDC
YXXXXXXXXXXXXX------------------XXXXXXXXXXXXXXX-XXXXXXXXXXXX
XXXXXXXXXXXXXXXXLLDSL-----------SLVQGGLPGSGVPSELPQLIPVFPGGTP
LLPPVVGGSIPVSSPLPPASFGLVMDPSKKLAA-SVLDALDPPGSA-----LDSLD----
---LLPYSETRL--DALDSFGP-TRGSLDKPSSFMEDAN----------SQDHRPL----
--------S-----S-TQKPAP------------SPEPSMPNT----ALLIKNPLAATHE
FKQACQLCYPKT-GPRAGDYTYREGLEHKCKRDILLGRLRSSEDQT-------WKRIRPR
PTKTSFV

PF00642 // ENSGT00390000018542_0_Domain_2 (668, 694)

GSYYLCKDMINKQDCKYGDNCTFAYH

ENSGT00390000018542_0_Linker_2_3 (694, 800)

QEEIDVWTEERKGTLNRDLLFDPLGGV
KRGSLTIAKLLKEHQGIFTFLCEICFDSKPRIISKGTKDSPSVCSNLAAKHSFYNNKCLV
HIVRSASLKYSKIRQFQEH

PF00642 // ENSGT00390000018542_0_Domain_3 (800, 825)

FQFDVCRHEVRYGCLREDSCHFAHS

ENSGT00390000018542_0_Linker_3_4 (825, 948)

FIELRVWLLQQYS-GM
THEDIVQESKKYWQQMEAHAGKASS-SLGASRAHGPSTFDLQMKFVCGQCWRNGQVVE-P
DKDLKYCSA--KARHCWTKERRVLLVMSKAKRKWVSVRPLPSIRNFP

PF00642 // ENSGT00390000018542_0_Domain_4 (948, 974)

QQYDLCIHAQNGR
KCQYVGNCSFAHS

ENSGT00390000018542_0_Linker_4_5 (974, 1105)

PEERDMWTFMKE------------NKI------LDMQQTY---DMWL
-KKHNPGKPGEGTPISSREGEKQIQMPTDYADI---MMGYHCWLCGKNSNSKKQWQQHIQ
SEKHKEKVFTSDSDASGWAYRFPM

PF00642 // ENSGT00390000018542_0_Domain_5 (1105, 1138)

GEFRLCD-------RLQKGKACPDGDKCRCAHGQEE
LNEWLDRREVLKQKLAKARKDMLLCPRDDDFGKYNFLLQEDGDAAGAA----PEAPTAAP
AAVAGE------------------------------------------------------
----------------------

-------------------------------------------MERQKRKADIEKGLQFI
QSTL-PL--KQEEYEAFLLKLVQNLFAEGNDLFREKDYKQALVQYMEGL-NVADYAASDQ
VALPRELLCKLHV--NRAACYFTMGLYEKALEDSEKALGLDGESIRALFRKARALNELGR
HKEAYECSSRCSLALPHDENVTQLGQELAQ------KLGLRVRKAYKRPQ-ELETFSLLS
N--GAPAGL---------TDQGTSNGLGSIDDIE-----------------------TDC
YVDLRGSPALLPST------------------PTMPLFPHVLDLLAPLDGSSRTLPGTEG
LDDFSDGDVFGPELDTLLDSL-----------SLVQGGLPGSGMPSELPQLIPVFPGGTP
LLPPVVGGSIPVSSPLPPASFGLVMDPSRKLAA-SVLDALDSPGPT-----LDPLD----
---LLPYSEARL--GALDSFGS-ARGSLDKPDSFLEETSSQ--------D--HRPP----
--------S-----S-TQKPAP------------SPEPSMPNT----TLLIKNPLAATHE
FKQACQLCYPKT-GPRAGDYTYREGLEHKCRRDVLLGRLRSSENQI-------WKRIRPR
PTKTSFVGSYYLCKDMINKQDCKYGDNCTFAYHQEEIDVWTEERKGTLNRDLLFDPLGGV
KRGSLTIAKLLKEHQGIFTFLCEICFDSKPRIISKGTKDSPSVCSNLAAKHSFYNNKCLV
HIVRSTSLKYSKIRQFQEHFQFDVCRHEVRYGCLREDSCHFAHSFIELKVWLLQQYS-GM
THEDIVQESKKYWQQMEAHAGKASS-GLGTPRTHGPSTFDLQMKFVCGQCWRNGQVVE-P
DKDLKYCSA--KARHCWTKERRVLLVMSKAKRKWVSVRPLPSIRNFPQ

PF00642 // ENSGT00390000018542_0_Domain_4 (949, 974)

QYDLCIHAQNGR
KCQYVGNCSFAHS

ENSGT00390000018542_0_Linker_4_5 (974, 1108)

PEERDMWTFMKE------------NKI------LDMQQTY---DMWL
-KKHNPGKPGEGTPISSREGEKQIQMPTDYADI---MMGYHCWLCGKNSNSKKQWQQHIQ
SEKHKEKVFTSDSDASGWAYRFPMGEF

PF00642 // ENSGT00390000018542_0_Domain_5 (1108, 1138)

RLCD-------RLQKGKACPDGDKCRCAHGQEE
LNEWLDRREVLKQKLAKARKDMLLCPRDDDFGKYNFLLQEDGDT----TGATPDAPVAAT
ATAATT---TTGE-----------------------------------------------
----------------------

-------------------------------------------MERQRRKADIEKGLQFI
QSTL-PL--KQEEYEAFLLKLVQNLFAEGNXXXXXXXXXXXXXXXXXXXXXXXXXX---X
XXXXXXXXXXXXXXXXXXXXXXXXGLYEKALEDSEKALGLDGENIRALFRKARALTELGR
HKEAYECSSRCSLTLPHDESVTQLGQELAQ------KLGLRVRKAYKRPQ-ELETFSLLS
N--GTTTGV---------ADQXXXXXXXXXXXXXX-XXXXXXXXXXXX--XXXXXXXXXX
XXXXXX---XX--X------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX-----------SLVQGGLPVSGVPSELPQLIPVFPGGTP
LLPPVVGGSIPVSSPLPPASFGLVMDPSKKLAA-SVLDALDPPGST-----RDSLD----
---LLPYSETRL--DALDSFGS-ARGSLDQPDSFMEETSSQDHPLS--------------
--------------G-TQKPA------------SSPEPSMPNT----ALLIKNPLAATHE
FKQACQLCYPKT-GPRAGDYTYREGLEHKCKRDTLLGRLRSVEDQT-------WKRIRPR
PTKTSFV

PF00642 // ENSGT00390000018542_0_Domain_2 (668, 694)

GSYYLCKDMINKQDCKYGDNCTFAYH

ENSGT00390000018542_0_Linker_2_3 (694, 800)

QEEIDVWTEERKGTLNRDLLFDPLGGV
KRGSLTIAKLLKEHQGIFTFLCEICFDSKPRIISKGTKDSPSVCSNLAAKHSFYNNKCLV
HIVRSTSLKYSKIRQFQEH

PF00642 // ENSGT00390000018542_0_Domain_3 (800, 825)

FQFDVCRHEVRYGCLREDSCHFAHS

ENSGT00390000018542_0_Linker_3_4 (825, 948)

FIELKVWLLQQYS-GM
THEDIVQESKKYWQQIEIHAGKANS-SLGTPRTHGPSTFDLQMKFVCGQCWRNGQVVE-P
DKDLKYCSA--KARHCWTKERRVLLVMSKAKRKWVSVRPLPSIRNFP

PF00642 // ENSGT00390000018542_0_Domain_4 (948, 974)

QQYDLCIHAQNGR
KCQYVGNCSFAHS

ENSGT00390000018542_0_Linker_4_5 (974, 1105)

PEERDMWTFMKE------------NKI------LDMQQTY---DMWL
-KKHNPGKPGEGTPITSREGEKQIQMPTDYADI---MMGYHCWLCGKNSNSKKQWQQHIQ
SEKHKEKVFTSDSDTNGWAYRFPM

PF00642 // ENSGT00390000018542_0_Domain_5 (1105, 1138)

GEFRLCD-------RLQKGKACPDGDKCRCAHGQEE
LNEWLDRREVLKQKLAKARKDMLLCPRDDDFGKYNFLLQEDGGTSGAS----PEAPAAAA
AAVTRE------------------------------------------------------
----------------------

-------------------------------------------MERQKRKADIEKGLQFI
QSTL-PL--KQEEYEAFLLKLVQNLFAEGNDLFREKDYKQALVQYMEGL-NVADYAASDQ
VALPRELLCKL

PF13181 // ENSGT00390000018542_0_Domain_0 (132, 162)

HV--NRAACYFTMGLYEKALEDSEKALGLDSESIRALFRKARALNELGR
HKEAYECSSRCSLALPHDESVTQLGQELAQ------KLGLRVRKAYKRPQ-ELE--TFSL
LSNGTAAGV---------ADQGTSNGLGSIDDIE-----------------------TDC
YVDPRASPALLPST------------------PTMPLFPHVLDLLAPLDS-SRTLPSTDS
LDDFSDGDVFGPELDTLLDSL-----------SLVQGGLSGSGVPSELPQLIPVFPGGTP
LLPPVVGGSIPVSSPLPPASFGLVMDPSKKLAA-SVLDALDPPGPT-----LDPLD----
---LLPYSETRL--DALDSFGS-TRGSLDKPDCFVEETNSQ--------D--HRPP----
--------S-----G-AQ------------KPAPSPEPCMPNT----ALLIKNPLAATHE
FKQACQLCYPKT-GPRAGDYTYREGLEHKCKRDILLGRLRSSEDQT-------WKRIRPR
PTKTSFVGSYYLCKDMINKQDCKYGDNCTFAYHQEEIDVWTEERKGTLNRDLLFDPLGGV
KRGSLTIAKLLKEHQGIFTFLCEICFDSKPRIISKGTKDSPSVCSNLAAKHSFYNNKCLV
HIVRSTSLKYSKIRQFQEHFQFDVCRHEVRYGCLREDSCHFAHSFIELKVWLLQQYS-GM
THEDIVQESKKYWQQMEAHAGKASS-SMGAPRTHGPSTFDLQMKFVCGQCWRNGQVVE-P
DKDLKYCSA--KARHCWTKERRVLLVMSKAKRKWVSVRPLPSIRNFPQ

PF00642 // ENSGT00390000018542_0_Domain_4 (949, 974)

QYDLCIHAQNGR
KCQYVGNCSFAHS

ENSGT00390000018542_0_Linker_4_5 (974, 1108)

PEERDMWTFMKE------------NKI------LDMQQTY---DMWL
-KKHNPGKPGEGTPISSREGEKQIQMPTDYADI---MMGYHCWLCGKNSNSKKQWQQHIQ
SEKHKEKVFTSDSDASGWAFRFPMGEF

PF00642 // ENSGT00390000018542_0_Domain_5 (1108, 1138)

RLCD-------RLQKGKACPDGDKCRCAHGQEE
LNEWLDRREVLKQKLAKARKDMLLCPRDDDFGKYNFLLQEDGDP----AGAT--PEAPAA
AAAAT-----TTGE----------------------------------------------
----------------------

------------------------------------------------------------
-STL-PL--KQEEYEAFLLKLVQNLFAEGNDLFREKDYKQALVQYMEGL-NVADYAASDQ
VSLPRELLCKLHV--NRAACYFTMGMYEKSLEDSEKALGLDSENIRALFRKARALNELGR
HKEAYECSSRCSLALPHDESVTQLGQELAQ------KLGLRVRKAYKRPR-ELETFSLLS
N--GTAAGV---------ADQGMSNGFGSIDDIE-----------------------TDC
YVDLHSSPALLPSA------------------PAMSLFPHVLDLLAPLDSSGRAIPSTEG
LDDFSDGDVFGPELDTLLDSL-----------SLVQGGLPGSGVPSELPQLIPVFPGGTP
LLPPVVGGSIPVSSPLPPASFGLVIDPSKKLTA-SVLDTLDAPGPA-----LDPLD----
---LLPYSDTRL--EALDTFGS-VRGSLDKPDSFIEETNSQ--------D--HRPP----
--------S-----S-TQKPAP------------SPEPSMPNT----ALLIKNPLAATHE
FKQACQLCYPKT-GPKAGDYTYREGLEHKCKRDILLGRLRSSEDQA-------WKRIRPR
PTKTSFVGSYYLCKDMINKQDCKYGDNCTFAYHQEEIDVWTEERKGTLNRDLLFDPLGGV
KRGSLTIAKLLKEHQGIFTFLCEICFDSKPRIISKGTKDSPSVCSNLAAKHSFYNNKCLV
HIVRSTSLKYSKIRQFQEHFQFDVCRHEVRYGCLREDSCHFAHSFIELKVWLLQQYS-GM
THEDIVQESKKYWQQMEAHAGKASG-SMGGPRTHGPSTFDLQMKFVCGQCWRNGQVVE-P
DKDLKYCSA--KARHCWTKERRVLLVMSKAKRKWVSVRPLPSIRNFPQ

PF00642 // ENSGT00390000018542_0_Domain_4 (949, 974)

QYDLCIHAQNGR
KCQYVGNCSFAHS

ENSGT00390000018542_0_Linker_4_5 (974, 1108)

PEERDMWTFMKE------------NKI------LDMQQTY---DMWL
-KKHNPGKPGEGTPISSREGEKQIQMPTDYADI---MMGYHCWLCGKNSNSKKQWQQHIQ
SEKHKEKVFTSDSDASGWAYRFPMGEF

PF00642 // ENSGT00390000018542_0_Domain_5 (1108, 1138)

RLCD-------RLQKGKACPDGDKCRCAHGQEE
LNEWLDRREVLKQKLAKARKDMLLCPRDDDFGKYNFLLQEDGDT----AGATPEASAAAP
AAAATTP----TGE----------------------------------------------
----------------------

-------------------------------------------MERQKRKADIEKGLQFI
QSTL-PL--KQEEYEAFLLKLVQNLFAEGNDLFREKDYKQALVQYMEGL-NVADYAASDQ
VALPQELLCKLHV--NRAACYFTMGLYEKALEDSEKALLLDSESIRALFRKARALNELGR
HKEAYECSSRCSLALPHDESVTQLGQELAQ------KLGLRVRKAYKRPQ-ELE--TFSL
LSNGTAAGV---------ADQGTSNGLGSIDDIE-----------------------TDC
YVDLRGSPALLPST------------------PTMPLFPHVLDLLAPLDSSSRTLPSTES
LDDFSDGDVFGPELDTLLDSL-----------SLVQGGLPGSGVPSELPQLIPVFPGGTP
LLPPVVGGSIPVSSPLPPASFGLVMDPSKKLAA-SVLDALDPPGPT-----LDSLD----
---LLPYSETRL--DALDSFGS-ARGSLDKPDSFMEENNSQ--------D--HRPP----
--------S-----S-TQ------------KPAPSPEPSMPNT----ALLIKNPLAATHE
FKQACQLCYPKT-GPRAGDYTYREGLEHKCKRDILLGRLRSSEDQS-------WKRIRPR
PTKTSFVGSYYLCKDMINKQDCKYGDNCTFAYHQEEIDVWTEERKGTLNRDLLFDPLGGV
KRGSLTIAKLLKEHQGIFTFLCEICFDSKPRIISKGTKDSPSVCSNLAAKHSFYNNKCLV
HIVRSTSLKYSKIRQFQEHFQFDVCRHEVRYGCLREDSCHFAHSFIELKVWLLQQYS-GM
THEDIVQESKKYWQQMEAHAGKASS-SLGAPRTHGPSTFDLQMKFVCGQCWRNGQVVE-P
DKELKYCSA--KARHCWTKERRVLLVMSKAKRKWVSVRPLPSIRNFPQ

PF00642 // ENSGT00390000018542_0_Domain_4 (949, 974)

QYDLCIHAQNGR
KCQYVGNCSFAHS

ENSGT00390000018542_0_Linker_4_5 (974, 1108)

PEERDMWTFMKE------------NKI------LDMQQTY---DMWL
-KKHNPGKPGEGTPISSREGEKQIQMPTDYADI---MMGYHCWLCGKNSNSKKQWQQHIQ
SEKHKEKVFTSDSDASGWAYRFPMGEF

PF00642 // ENSGT00390000018542_0_Domain_5 (1108, 1138)

RLCD-------RLQKGKTCPDGDKCRCAHGQEE
LNEWLDRREVLKQKLAKARKDMLLCPRDDDFGKYNFLLQEDGDT----AGAT--PEAPAG
AAAVT-----TIGE----------------------------------------------
----------------------

-------------------------------------------MERQKRKADIEKGLQFI
QSTL-PL--KQEEYEAFLLKLVQNLFAEGNDLFREKDYKQALVQYMEGL-NVADYAASDQ
VALPRELL

PF00515 // ENSGT00390000018542_0_Domain_0 (129, 164)

CKLHV--NRAACYFTMGLYEKALEDSEKALGLDGE

ENSGT00390000018542_0_Linker_0_1 (164, 165)

S

PF00515 // ENSGT00390000018542_0_Domain_1 (165, 198)

IRALFRKARALNELGR
HKEAYECSSRCSLALPH

ENSGT00390000018542_0_Linker_1_2 (198, 668)

DESVTQLGQELAQ------KLGLRVRKAYKRPQ-ELETFSLLS
N--GNAAGM---------TDQGTSNGLGSIDDIET-GSVCNRG----------GVEAGVC
YVDLHGSPALLPTA------------------PTTPLFPHVLDLLAPLDSGIRALPGSES
LDDFSDGDVFGPELDTLLDSL-----------PLVQGGLPGSGVPSELPKLILVFPGGTP
LLPPVVGGSIPDSSPLPPASFGLVMNPSRKLAA-SVLDVLEPPGPT-----LDALN----
---LLPYSETRL--DTLETFES-TRSSLDKPDSFLEETNSQ--------D--HQPP----
--------G-----S-AQKPVP------------SPEPSMPNT----ALLIKNPLAATHE
FKQACQLCYPKT-GPRAGDYTYREGLEHKCKRDILLGRLRSAEDQA-------WKRIRPR
PTKTSFV

PF00642 // ENSGT00390000018542_0_Domain_2 (668, 694)

GSYYLCKDMINKQDCKYGDNCTFAYH

ENSGT00390000018542_0_Linker_2_3 (694, 800)

QEEIDVWTEERKGTLNRDLLFDPLGGV
KRGSLTIAKLLKEHQGIFTFLCEICFDSKPRIISKGTKDSPSVCSNLAAKHSFYNNKCLV
HIVRSTSLKYSKIRQFQEH

PF00642 // ENSGT00390000018542_0_Domain_3 (800, 825)

FQFDVCRHEVRYGCLREDSCHFAHS

ENSGT00390000018542_0_Linker_3_4 (825, 948)

FIELKVWLLQQYS-GM
THEDIVQESKKHWQQMEAHASKASG-GLGVPRSHGPSTFDLQMKFVCGQCWRNGQVVE-P
DKDLKYCSA--KARHCWTKERRVLLVMSKAKRKWVSVRPLPSIRNFP

PF00642 // ENSGT00390000018542_0_Domain_4 (948, 974)

QQYDLCIHAQNGR
KCQYVGNCSFAHS

ENSGT00390000018542_0_Linker_4_5 (974, 1105)

PEERDMWTFMKE------------NKI------LDMQQTY---DMWL
-KKHNPGKPGEGTPISSREGEKQIQMPTDYADI---MMGYHCWLCGKNSNSKKQWQQHIQ
SEKHKEKVFTSDSDASGWTFRFPM

PF00642 // ENSGT00390000018542_0_Domain_5 (1105, 1138)

GEFRLCD-------RLQKGKVCPDGDKCRCAHGQAE
LSEWLDRREVLKQKLAKARKDMLLCPRDDDFGRYNFLLQEDGDA----ARAAPEAPAAAT
IATTGE------------------------------------------------------
----------------------

-------------------------------------------MERQKRKADIEKGLQFI
QSTL-PL--KQEEYEAFLLKLVQNLFAEGNDLFREKDYKQALVQYMEGL-NVADYAASDQ
VALPRELLCKL

PF13181 // ENSGT00390000018542_0_Domain_0 (132, 162)

HV--NRAACYFTMGLYEKALEDSEKALGLDSESIRALFRKARALNELGR
HKEAYECSSRCSLALPHDESVTQLGQELAQ------KLGLRVRKAYKRPQ-ELETFSLLS
N--GTAAAM---------ADQGTSNGLGSIDDIE-----------------------TDC
YVDLRGSPALLPST------------------PTMPLFPHVLDLLAPLDSSSRTAPSTEN
LDDFSDGDVFGPELDTLLDSL-----------SLVQGGLPGGSMPSELPQLIPVFPGGTP
LLPPVVGGSIPVSSPLPPASFGLVMDPSKKLAA-SVLDALDPPGPT-----LDPLD----
---LLPYSETRL--DALDSFGS-ARGSLDKPDSFMEETNSQ--------E--HRPP----
--------S-----S-TQKPAP------------SGLPSSSAP----L-------SSAQ-
--THSVPVPHAP-GPRAGDYTYREGLEHKCKRDILLGRLRSAEDQT-------WKRIRPR
PTKTSFVGSYYLCKDMINKQDCKYGDNCTFAYHQEEIDVWTEERKGTLNRDLLFDPLGGV
KRGSLTIAKLLKEHQGIFTFLCEVPTK---------NDSSPASCPSLAAS-----HRCLV
HIVRSTSLKYSKIRQFQEHFQFDVCRHEVRYGCLREDSCHFAHSFIELKVWLLQQYS-GM
THEDIVQESKKYWQQMEAHAGKASS-SSGAPRTHGPSTFDLQMKFVCGQCWRNGQVVE-P
DKDLKYCSA--KARHCWTKERRVLLVMSKAKRKWVSVRPLPSIRNFPQ

PF00642 // ENSGT00390000018542_0_Domain_4 (949, 974)

QYDLCIHAQNGR
KCQYVGNCSFAHS

ENSGT00390000018542_0_Linker_4_5 (974, 1108)

PEERDMWTFMKE------------NKI------LDMQQTY---DMWL
-KKHNPGKPGEGTPISSREGEKQIQMPTDYADI---MMGYHCWLCGKNSNSKKQWQQHIQ
SEKHKEKVFTSDSDASGWAYRFPMGEF

PF00642 // ENSGT00390000018542_0_Domain_5 (1108, 1138)

RLCD-------RLLKGKACPDGDKCRCAHGQEE
LSEWLDRREVLKQKLAKARKDMLLCPRDDDFGKYNFLLQEDAEA----ASAAPEVPAAAA
AAATTTTTTTTATTTAAE------------------------------------------
----------------------

-------------------------------------------MERQKRKEEIEKGLQFI
QSTI-SL--KQEDYEAFLHKLVWNLFAEGNDLFREKDFKQALVQYVEGL-NVADYAASDE
VTLPRELL

PF07719 // ENSGT00390000018542_0_Domain_0 (129, 164)

CKLHV--NRAACYFSMGLYEKALEDSEKALGLDPE

ENSGT00390000018542_0_Linker_0_1 (164, 165)

N

PF00515 // ENSGT00390000018542_0_Domain_1 (165, 187)

IRALFRKASSLNELGR
HKEAYE

ENSGT00390000018542_0_Linker_1_2 (187, 668)

CSKTCSISLPHDESVTQLSRELAQ------KLRLPCRKAYKRPQ-XXXXXXXXX
XXXX--X---------XXXXXGTSNGLGSIDDIE----------------------TGNC
SMDLRCLTAPLHP------------------WPTTTLFPPTTDLLA----PPDG-T--ES
TEDFSDGDVFGPELDSLLDSLF-----------LVQVHS-S-YVSSEMPQRIPVFPGGAP
LLPPVVSGTIPVSNPLPPASFGLVMDPTKKMAS-SMLEACDSPASS-----VDTLD--PL
D--LPPYTQAHL--EALDSFGP-VRGSQDTLDSFTVEDTSSQDLRPSSSTQKLP------
---------------------------------PAQESTMPNT----ALLVKNPLASSHL
FKQACHLCYPKT-GPKAGDYTYREDLEHTCKRDILLGRIRNSEDKT-------WKRIRPR
PTKTNFI

PF00642 // ENSGT00390000018542_0_Domain_2 (668, 694)

GSYFLCKDMLNKQDCKYGDNCTFAYH

ENSGT00390000018542_0_Linker_2_3 (694, 800)

QEEIDV--GERKGTLNRDLF--DLGGV
KRGSLTIAKLLKEHQGIFTFLCEICFDSKPRIISKGTKDSPAVCSNLAAKHSFHDNKCLV
HIVRSTALKYSKIRQFQEH

PF00642 // ENSGT00390000018542_0_Domain_3 (800, 825)

FQFDVCRHEVRYGCLREDSCHFAHS

ENSGT00390000018542_0_Linker_3_4 (825, 948)

FIELKVWLLQQYS-GM
THEDIVQESKKCWQQMEAHAGKTANSL--------PSTFDLQMKFVCGQCWRNGQVVE-P
DKDFKYCSA--KARHCWTKERRVLLVMSKVKRKWVSVRPLPSIRSFP

PF00642 // ENSGT00390000018542_0_Domain_4 (948, 974)

QQYDLCIHAQNGR
KCQYVGNCSFAHS

ENSGT00390000018542_0_Linker_4_5 (974, 1105)

PEERDMWTFMKE------------NKI------LDMQQTY---DMWL
-KKHNPGKPGEGTQVTSREGEKQIQMPTDYADI---MMGFHCWLCGKNSNSKKQWQQHIQ
SEKHKEKVFTSDSDSSCWTFRFPM

PF00642 // ENSGT00390000018542_0_Domain_5 (1105, 1138)

GEFRLCER-------FQKKKACPDGEKCRCAHGQEE
LTEWLDRREVLKQKLAKARKDMLLCPMDNDFGKYNFLLQDN-------------------
------------------------------------------------------------
----------------------

-------------------------------------------MERQKRKADIEKGLQFI
QSTL-PL--KQEEYEAFLLKLVQNLFAEGNDLFREKDYKQALVQYMEGL-NVADYAASDQ
VALPRELLCK

PF13181 // ENSGT00390000018542_0_Domain_0 (131, 162)

LHV--NRAACYFTMGLYEKALEDSEKALGLDSESIRALFRKARALNELGR
HKEAYECSSRCSLALPHDESVTQLGQELAQ------KLGLRVRKAYKRPQ-ELE--TFSL
LSNGTAAGV---------ADQGTSNGLGSIDDIE-----------------------TDC
YVDPRGSPALLPST------------------PTMPLFPHVLDLLAPLDS-SRTLPSTES
LDDFSDGDVFGPELDTLLDSL-----------SLVQGGLSGSGVPSELPQLIPVFPGGTP
LLPPVVGGSIPVSSPLPPASFGLVMDPSKKLAA-SVLDALDPPGPT-----LDPLD----
---LLPYSETRL--DALDSFGS-TRGSLDKPDSFMEETNSQ--------D--HRPP----
--------S-----G-AQ------------KPTPSPEPCMPNT----ALLIKNPLAATHE
FKQACQLCYPKT-GPRAGDYTYREGLEHKCKRDILLGRLRSSEDQT-------WKRIRPR
PTKTSFVGSYYLCKDMINKQDCKYGDNCTFAYHQEEIDVWTEERKGTLNRDLLFDPLGGV
KRGSLTIAKLLKEHQGIFTFLCEICFDSKPRIISKGTKDSPSVCSNLAAKHSFYNNKCLV
HIVRSTSLKYSKIRQFQEHFQFDVCRHEVRYGCLREDSCHFAHSFIELKVWLLQQYS-GM
THEDIVQESKKYWQQMEAHAGKASS-SMGAPRTHGPSTFDLQMKFVCGQCWRNGQVVE-P
DKDLKYCSA--KARHCWTKERRVLLVMSKAKRKWVSVRPLPSIRNFPQ

PF00642 // ENSGT00390000018542_0_Domain_4 (949, 974)

QYDLCIHAQNGR
KCQYVGNCSFAHS

ENSGT00390000018542_0_Linker_4_5 (974, 1108)

PEERDMWTFMKE------------NKI------LDMQQTY---DMWL
-KKHNPGKPGEGTPISSREGEKQIQMPTDYADI---MMGYHCWLCGKNSNSKKQWQQHIQ
SEKHKEKVFTSDSDASGWAFRFPMGEF

PF00642 // ENSGT00390000018542_0_Domain_5 (1108, 1138)

RLCD-------RLQKGKACPDGDKCRCAHGQEE
LNEWLDRREVLKQKLAKARKDMLLCPRDDDFGKYNFLLQEDGDL----AGAT--PEAPAA
AATAT-----TGE-----------------------------------------------
----------------------

-------------------------------------------MERQKRKADIEKGLQFI
QSTL-PL--KQEEYEAFLLKLVQNLFAEGNDLFREKDYKQALVQYMEGL-NVADYAASDQ
VALPRELLCK

PF13181 // ENSGT00390000018542_0_Domain_0 (131, 162)

LHV--NRAACYFTMGLYEKALEDSEKALGLDSESIRALFRKARALNELGR
HKEAYECSSRCSLALPHDESVTQLGQELAQ------KLGLRVRKAYKRPQ-ELE--TFSL
LSNGTAAGV---------ADQGTSNGLGSIDDIE-----------------------TDC
YVDPRGSPALLPST------------------PTMPLFPHVLDLLAPLDS-SRTLPSTDS
LDDFSDGDVFGPELDTLLDSL-----------SLVQGGLSGSGVPSELPQLIPVFPGGTP
LLPPVVGGSIPVSSPLPPASFGLVMDPSKKLAA-SVLDALDPPGPT-----LDPLD----
---LLPYSETRL--DALDSFGS-TRGSLDKPDSFMEETNSQ--------D--HRPP----
--------S-----G-AQ------------KPAPSPEPCMPNT----ALLIKNPLAATHE
FKQACQLCYPKT-GPRAGDYTYREGLEHKCKRDILLGRLRSSEDQT-------WKRIRPR
PTKTSFVGSYYLCKDMINKQDCKYGDNCTFAYHQEEIDVWTEERKGTLNRDLLFDPLGGV
KRGSLTIAKLLKEHQGIFTFLCEICFDSKPRIISKGTKDSPSVCSNLAAKHSFYNNKCLV
HIVRSTSLKYSKIRQFQEHFQFDVCRHEVRYGCLREDSCHFAHSFIELKVWLLQQYS-GM
THEDIVQESKKYWQQMEAHAGKASS-SMGAPRTHGPSTFDLQMKFVCGQCWRNGQVVE-P
DKDLKYCSA--KARHCWTKERRVLLVMSKAKRKWVSVRPLPSIRNFPQ

PF00642 // ENSGT00390000018542_0_Domain_4 (949, 974)

QYDLCIHAQNGR
KCQYVGNCSFAHS

ENSGT00390000018542_0_Linker_4_5 (974, 1108)

PEERDMWTFMKE------------NKI------LDMQQTY---DMWL
-KKHNPGKPGEGTPISSREGEKQIQMPTDYADI---MMGYHCWLCGKNSNSKKQWQQHIQ
SEKHKEKVFTSDSDTSGWAFRFPMGEF

PF00642 // ENSGT00390000018542_0_Domain_5 (1108, 1138)

RLCD-------RLQKGKACPDGDKCRCAHGQEE
LNEWLDRREVLKQKLAKARKDMLLCPRDDDFGKYNFLLQEDGDL----AGAT--PEGPAA
AATAT-----TGE-----------------------------------------------
----------------------

-------------------------------------------MERQRRKADIEKGLQFI
QSTL-PL--KQEEYEAFLLKLVQNLFAEGNDLFREKDYKQALVQYMEGL-NVADYAASDQ
VALPQELL

PF00515 // ENSGT00390000018542_0_Domain_0 (129, 164)

CKLHV--NRAACYFTMGLYEKALEDSEKALGLDGE

ENSGT00390000018542_0_Linker_0_1 (164, 165)

N

PF00515 // ENSGT00390000018542_0_Domain_1 (165, 198)

IRALFRKARALSELGR
HKEAYECSSRCSLARPH

ENSGT00390000018542_0_Linker_1_2 (198, 668)

DESVTQLGQELAQ------KLGLRVRKAYKRPQ-ELETFSLLS
N--GTAAGG---------ADQGTSNGLGSIDDIET-GNIPDLRAQC------GDGSPADC
YVDLRGSPAPLPST------------------PTMPLFPHVLDLLAPLDSSSRALPGTES
LDDFSDGDVFGPELDTLLDSL-----------SLVQGGLPGSGVPSELPQLIPVFPGGTP
LLPPVVGGSIPVSSPLPPASFGLVMDPSKKLAA-SVLDALDPPGSA-----LDSLD----
---LLPYSDTRL--DALDNFGS-TRGALDKPNSFV----------EETNSQDHRPP----
--------S-----G-TQKPAP------------SPEPSMPNT----ALLIKNPLAATHE
FKQACQLCYPKT-GPRAGDYTYREGLEHKCKRDILLGRLRSSEDQT-------WKRIRPR
PTKTSFV

PF00642 // ENSGT00390000018542_0_Domain_2 (668, 694)

GSYYLCKDMINKQDCKYGDNCTFAYHQEEIDVWTEERKGTLNRDLLFDPLGGV
KRGSLTIAKLLKEHQGIFTFLCEICFDSKPRIISKGTKDSPSVCSNLAAKHSFYNNKCLV
HIVRSTSLKYSKIRQFQEHFQFDVCRHEVRYGC------HFAHSFIELKVWLLQQYS-GM
THEDIVQESKKYWQQMEAHAGKASSGL-GTPRTHGPSTFDLQMKFVCGQCWRNGQVVE-P
DKDLKYCSA--KARHCWTKERRVLLVMSKAKRKWVSVRPLPSIRNFP

PF00642 // ENSGT00390000018542_0_Domain_4 (948, 974)

QQYDLCIHAQSGR
KCQYVGNCSFAHS

ENSGT00390000018542_0_Linker_4_5 (974, 1105)

PEERDMWTFMKE------------NKI------LDMQQTY---DMWL
-KKHNPGKPGEGTPISSREGEKQIQMPTDYADI---MMGYHCWLCGKNSNSKKQWQQHIQ
SEKHKEKVFTSDSDASGWAYRFPM

PF00642 // ENSGT00390000018542_0_Domain_5 (1105, 1138)

GEFRLCD-------RLQKGKACPDGDKCRCAHGQEE
LTEWLDRREVLKQKLAKARKDMLLCPRDDDFGKYNFLLQEDENT----AGATPEAPVAAT
VTGE--------------------------------------------------------
----------------------

-------------------------------------------MERQKRKADIEKGLQFI
QSTL-PL--KQEEYEAFLLKLVQNLFAEGNDLFREKDYKQALVQYMEGL-NVADYAASDQ
VALPRELLCK

PF13181 // ENSGT00390000018542_0_Domain_0 (131, 162)

LHV--NRAACYFTMGLYEKALEDSEKALGLDSESIRALFRKARALNELGR
HKEAYECSSRCSLALPHDESVTQLGQELAQ------KLGLRVRKAYKRPQ-ELETFSLLS
N--GTAAGV---------ADQQCSPSS-------------------------LAYPTADC
YVDPRASPALLPST------------------PTMPLFPHVLDLLAPLDS-SRTLPSTDS
LDDFSDGDVFGPELDTLLDSL-----------SLVQGGLSGSGVPSELPQLIPVFPGGTP
LLPPVVGGSIPVSSPLPPASFGLVMDPSKKLAA-SVLDALDSPGPT-----LDPLD----
---LLPYSETRL--DALDSFGS-TRGSLDKPDCFVEETNSQ--------D--HRPP----
--------S-----G-AQKPAPSVMPTVASFLLSQPEPCMPNT----ALLIKNPLAATHE
FKQACQLCYPKT-GPRAGDYTYREGLEHKCKRDILLGRLRSSEDQT-------WKRIRPR
PTKTSFVGSYYLCKDMINKQDCKYGDNCTFAYHQEEIDVWTEERKGTLNRDLLFDPLGGV
KRGSLTIAKLLKEHQGIFTFLCEICFDSKPRIISKGTKDSPSVCSNLAAKHSFYNNKCLV
HIVRSTSLKYSKIRQFQEHFQFDVCRHEVRYGCLREDSCHFAHSFIELKVWLLQQYS-GE
GTDPFIHVRLGPWTTQEADQGV-TG-SRGAPRTHGPSTFDLQMKFVCGQCWRNGQVVE-P
DKDLKYCSA--KARHCWTKERRVLLVMSKAKRKWVSVRPLPSIRNFPQ

PF00642 // ENSGT00390000018542_0_Domain_4 (949, 974)

QYDLCIHAQNGR
KCQYVGNCSFAHS

ENSGT00390000018542_0_Linker_4_5 (974, 1108)

PEERDMWTFMKE------------NKI------LDMQQTY---DMWL
-KKHNPGKPGEGTPISSREGEKQIQMPTDYADI---MMGYHCWLCGKNSNSKKQWQQHIQ
SEKHKEKVFTSDSDASGWAFRFPMGEF

PF00642 // ENSGT00390000018542_0_Domain_5 (1108, 1138)

RLCD-------RLQKGKACPDGDKCRCAHGQEE
LNEWLDRREVLKQKLAKARKDMLLCPRDDDFGKYNFLLQEDGDP----AGATPEAPAAAA
AATTTGE-----------------------------------------------------
----------------------

-------------------------------------------MERQKRKADIEKGLQFI
QSTL-PL--KQEEYEAFLLKLVQNLFAEGNDLFREKDYKQALVQYMEGL-NVADYAASDQ
VALPRELLC

PF00515 // ENSGT00390000018542_0_Domain_0 (130, 161)

KLHV--NRAACYFTMGLYEKALEDSEKALGLDNESIRALFRKARALNELGR
HKEAYECSSRCSLALPHDESVTQLGQELAQ------KLGLRVRKAYKRPQ-ELE--TFSL
LSNGTAAGV---------ADQGTSNGLGSLDDIE-----------------------TDC
YVDPRGSPALLPST------------------PTMPLFPHVLDLLAPLDS-IRTLPSTES
LDDFSDGDVFGPELDTLLDSL-----------SLVQGGLSGSGVPSELPQLIPVFPGGTP
LLPPVVGGSIPVSSPLPPASFGLVMDPSKKLAA-SVLDALDPPGPT-----LDPLD----
---LLPYSETRL--DALDSFGS-TRGSLDKPDSFMEETNSQ--------D--HRPP----
--------S-----G-AQ------------KPAPSPEPCMPNT----ALLIKNPLAATHE
FKQACQLCYPKT-GPRAGDYTYREGLEHKCKRDILLGRLRSSEDQI-------WKRIRPR
PTKTSFVGSYYLCKDMINKQDCKYGDNCTFAYHQEEIDVWTEERKGTLNRDLLFDPLGGV
KRGSLTIAKLLKEHQGIFTFLCEICFDSKPRIISKGTKDSPSVCSNLAAKHSFYNNKCLV
HIVRSTSLKYSKIRQFQEHFQFDVCRHEVRYGCLREDSCHFAHSFIELKVWLLQQYS-GM
THEDIVQESKKYWQQMEAHAGKASS-SMGAPRTHGPSTFDLQMKFVCGQCWRNGQVVE-P
DKDLKYCSA--KARHCWTKERRVLLVMSKAKRKWVSVRPLPSIRNFPQQYDLCIHAQNGR
KCQYVGNCSFAHSPEERDMWTFMKE------------NKI------LDMQQTY---DMWL
-KKHNPGKPGEGTPISSREGEKQIQMPTDYADI---MMGYHCWLCGKNSNSKKQWQQHIQ
SEKHKEKVFTSDSDASGWAFRFPMGEF

PF00642 // ENSGT00390000018542_0_Domain_5 (1108, 1138)

RLCD-------RLQKGKACPDGDKCRCAHGQEE
LNEWLDRREVLKQKLAKARKDMLLCPRDDDFGKYNFLLQEDGDP----ASAT--PEAPAA
AATAT-----TGE-----------------------------------------------
----------------------

-----------------------------------------IVMERQKRKQEIEKGLQLI
QSTL-PL--SQEDYEAVLQKLVRNLFAEGNDLFREKDFKLSLVQYVEGL-NVADYAASDE
VTIPKELL

PF07719 // ENSGT00390000018542_0_Domain_0 (129, 164)

CKLHV--NRAACYFAMGLYEKALEDSEKALGLDKE

ENSGT00390000018542_0_Linker_0_1 (164, 165)

N

PF00515 // ENSGT00390000018542_0_Domain_1 (165, 198)

IRALFRKARSLNELGR
HKEAYECNSRCLLSLPH

ENSGT00390000018542_0_Linker_1_2 (198, 668)

DESVTQLGQELAQ------KLGLRVRKAYKRPQNLISQQI-SG
NGYF--S-----------WVFFSFVNLEKIEILQRPEGC--------PH-RKKPNSIYR-
-------FAHVVGH---YAELVFLCSNKACPLLEMQ-TPDSPPSLNF--GRSSG-KVPDN
VEDFTDGDIIGEELDSLLDSLAEGSP-YP-L-ML----------------------WGTP
LLPPVVTASIPVSSPLPPASFGLVMDPTKQLSSSSVLDAFEPPPGGSGGSTLDSLD--SL
DLL--PYTDSRL--DALDSFGT-SRGSLDALDSFAIGLNGKGQA-------CPSEHFL--
----------------------PPYDKAGKDFPGVRKPVIPNT----ALLVKNPLASTHV
FKQACHICYPKT-GPKAGDYTYREGLEHKCKRDILLGRLKNSEDKT-------WKRIRPR
PTKTNFV

PF00642 // ENSGT00390000018542_0_Domain_2 (668, 694)

GSYYLCKDMLNKQDCKYGDNCTFAYH

ENSGT00390000018542_0_Linker_2_3 (694, 800)

QEEIDVWTEERKGTLNRDLLFDPLGGI
KQSNLTIAKLLKEHQGIFTFLCEICFDSKPRIISKGTKDTPSVCSNLSAKHSFHDNKCLV
HIVRSTSLKYSKIRQFQEH

PF00642 // ENSGT00390000018542_0_Domain_3 (800, 825)

FQFDVCRHEVRYGCLREDSCHFAHS

ENSGT00390000018542_0_Linker_3_4 (825, 948)

FIELKVWLLQQYS-GM
THEDIVQESKKYWQQMEAHASKPTNSM-LGEQILK-ACLYMEMKFVCGQCWRNGQLVE-P
DKDLKYCSA--KARHCWTKERRVLLVMSKAKKKWVSVRPLPSIRNFP

PF00642 // ENSGT00390000018542_0_Domain_4 (948, 974)

QQYDLCIHAQNGR
KCQYVGNCSFAHS

ENSGT00390000018542_0_Linker_4_5 (974, 1105)

PEERDMWTFMKE------------NKI------LDMQQTY---DMWL
-KKHNPGKPGEGTPLTSREGEKQIQMPTDYADI---MMGYHCWLCGKNSNSKKQWQQHIQ
SEKHKEKVFTSDSDSSCWSYRFPM

PF00642 // ENSGT00390000018542_0_Domain_5 (1105, 1138)

GEFQLCER-------FQKSKACPEGEECRYAHGQDE
LTEWLDRREVLKQKLAKARKDMLLCPRDDDFGKYNFLLRDGV------------------
------------------------------------------------------------
----------------------

-------------------------------------------MERQKRKQEIEKGLQFI
QSTL-PL--SQEDYEAFLQKLVRNLFAEGNDLFREKDFKLSLVQYVEGL-NVADYAASDE
VTIPKELLC

PF00515 // ENSGT00390000018542_0_Domain_0 (130, 164)

KLHV--NRAACYFAMGLYEKALEDSEKALSLDKENIRALFRKARSLNELGR
HKEAYECNSRCLLSLPHDESVTQLGQELAQ------KLGLRVRKAYKRPQ-ELETFSLLS
NGTS--I---------NSSNQTTSNGLGSIDDIE---TD--------CS-MD--------
---LQCLPAPVA---------------TSIPGLPTS-LPAASLIPSP--DCVPL-PVPEN
AEDFTDGDIIGEELDSLLDSLA--------E-GSLEGTIPT-NLPTEMPQLIPVFPGGTP
LLPPVVTASIPVSTPLPPASFGLVMDPTKQLSSSSVLDAFEAPPGGN------SLD--SL
DLL--PYTDTRL--DALDSFGT-SRGSLDTLDSFAIESSSP-ELRHPSGSQKTAPV----
-----------------------------------PEPVMPNT----ALLVKNPLASTHV
FKQACHICYPKT-GPKAGDYTYREGLEHKCKRDILLGRLKNSEDKT-------WKRIRPR
PTKTNFVGSYYLCKDMLNKQDCKYGDNCTFAYHQEEIDVWTEERKGTLNRDLLFDPLGGI
KQSSLTIAKLLKEHQGIFTFLCEICFDSKPRIISKGTKDTPSVCSNLSAKHIFHDNKCLV
HIVRSTSLKYSKIRQFQEHFQFDVCRHEVRYGCLREDSCHFAHSFIELKVWLLQQYS-GM
THEDIVQESKKYWQQVEAHASKPANSV-ASSRNPTSSTFDLQMKFVCGQCWRNGQLVE-P
DKDLKYCSA--KAPHCWTKERRVLLVMSKAKKKWVSVRPLPSIRNFPQQYDLCIHAQNGR
KCQYVGNCSFAHSPEERDMWTFMKE------------NKI------LDMQQTY---DMWL
-KKHNPGKPGEGTPLTSREGEKQIQMPTDYADI---MMGYHCWLCGN-SNSKKQWQQHIQ
SEKHKEKVFTSDSDSSCWSYRFPMGEF

PF00642 // ENSGT00390000018542_0_Domain_5 (1108, 1138)

RLCER-------FQKNKACPEGEECRYAHGQDE
LTEWLDRREVLKQKLAKARKDMLLCPRDDDFGKYNFLLRDD-------------------
------------------------------------------------------------
----------------------

-------------------------------------------MERQKRKQEIEKGLQFI
QSTL-PL--SQEDYEAFLQKLVRNLFAEGNDLFREKDFKLSLVQYVEGL-NVADYAASDE
VTIPKDLLC

PF00515 // ENSGT00390000018542_0_Domain_0 (130, 164)

KLHV--NRAACYFAMGLYEKALEDCEKALSLDKENIRALFRKARSLNELGR
HKEAYECNSRCLLSLSHDESVTQLGQELAQ------KLGLRVRKAYKRPQ-ELETFSLLS
NGTS--I---------NSSNQTTSNGLGSIDD-----------------------IETDC
SMDLQCLPAPVATSIPVSEGLDPLPSDSDAKGLPTS-LPAASLLPSP--DCVPL-PGPEN
TEDFTDGDIIGEELDSLLDSLAEGSP-YP-L-SLVQGTIPT-NLPTEMPQLIPVFPGGTP
LLPPVVTASIPVSTPLPPASFGLVMDPTKQLSSSSVLDAFEAPPGGSGSSTLDSLD--SL
DLL--PYTDTRL--DALDSFGT-SRGSLDTLDSFPIEETSSQELRHPPGSQKPAPVV---
--------------N-LGGVSHPAVPKATEHLLSQPEPVMPNT----ALLVKNPLASTHV
FKQACHICYPKT-GPKAGDYTYREGLEHKCKRDILLGRLKNSEDKT-------WKRIRPR
PTKTNFVGSYYLCKDMLNKQDCKYGDNCTFAYHQEEIDVWTEERKGTLNRDLLFDPLGGI
KQSSLTIAKLLKEHQGIFTFLCEICFDSKPRIISKGTKDTPSVCSNLSAKHIFHDNKCLV
HIVRSTSLKYSKIRQFQEHFQFDVCRHEVRYGCLREDSCHFAHSFIELKVWLLQQYS-GM
THEDIVQESKKYWQQMEAHASKPANNV-ASPRTPTSSTFDLQMKFVCGQCWRNGQLVE-P
DKDLKYCSA--KAPHCWTKERRVLLVMSKAKKKWVSVRPLPSIRNFPQQYDLCIHAQNGR
KCQYVGNCSFAHSPEERDMWTFMKE------------NKI------LDMQQTY---DMWL
-KKHNPGKPGEGTPLTSREGEKQIQMPTDYADI---MMGYHCWLCGKNSNSKKQWQQHIQ
SEKHKEKVFTSDSDSSCWSYRFPMGEF

PF00642 // ENSGT00390000018542_0_Domain_5 (1108, 1138)

RLCER-------FQKNKACPEGEECRYAHGQDE
LTEWLDRREVLKQKLAKARKDMLLCPRDDDFGKYNFLLRDDV------------------
------------------------------------------------------------
----------------------

-------------------------------------------MERQKRKEEIEKGLQFI
QSTI-SL--KQEDYEAFLHKLVWNLFAEGNDLFREKDFKQALVQYVEGL-NVADYAASDE
VTLPRELLC

PF00515 // ENSGT00390000018542_0_Domain_0 (130, 164)

KLHV--NRAACYFSMGLYEKALEDSEKALGLDPENIRALFRKASSLNELGR
HKEAYECSKTCSISLPHVSAGPEGLRPGQRGGWWSRAEKLRGGSPWVHPR-RWIP-----
-----------------------------------------------------------C
GFQ---------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

-------------------------------------------MERQKRKADIEKGLQFI
QSTL-PL--KQEEYEAFLLKLVQNLFAEGNDLFREKDYKQALVQYMEGL-NVADYAASDQ
VALPQELLCK

PF13181 // ENSGT00390000018542_0_Domain_0 (131, 162)

LHV--NRAACYFTMGLYEKALEDSEKALGLDSESIRALFRKARALNELGR
HKEAYECSSRCSLALPH-------------------------------------------
---------------------GTSNGLGSIDDIE-----------------------TDC
YVDLRGSPVLLPST------------------PTMPLFPHVLDLLAPLDSSSRAAPSTDS
LDDFSDGDVFGPELDTLLDSL-----------SLVQGGLPGGGVPSELPQLIPVFPGGTP
LLPPVVGGSIPVSSPLPPASFGLVMDPSKKLAA-SVLDALDPPGPT-----LDPLD----
---LLPYSETRL--DALDSFGS-ARGSLDKPDSFMEETNSQ--------E--HRPP----
--------S-----S-TQKPAP------------SPEPSMPNT----ALLIKNPLAATHE
FKQACQLCYPKT-GPRAGDYTYREGLEHKCKRDTLLGRLRSAEDQT-------WKRIRPR
PTKTSFVGSYYLCKDMINKQDCKYGDNCTFAYHQEEIDVWTEERKGTLNRDLLFDPLGGV
KRGSLTIAKLLKEHQGIFTFLCEICFDSKPRIISKGTKDSPSVCSNLAAKHGFYNNKCLV
HIVRSTSLKYSKIRQFQEHFQFDVCRHEVRYGCLREDSCHFAHSFIELKVWLLQQYS-GM
THEDIVQESKKYWQQMEAHAGKASS-GSGAPRTHGPSTFDLQMKFVCGQCWRNGQVVE-P
DKDLKYCSA--KARHCWTKERRVLLVMSKAKRKWVSVRPLPSIRNFPQ

PF00642 // ENSGT00390000018542_0_Domain_4 (949, 974)

QYDLCIHAQNGR
KCQYVGNCSFAHS

ENSGT00390000018542_0_Linker_4_5 (974, 1108)

PEERDMWTFMKE------------NKI------LDMQQTY---DMWL
-KKHNPGKPGEGTPISSREGEKQIQMPTDYADI---MMGYHCWLCGKNSNSKKQWQQHIQ
SEKHKEKVFTSDSDASGWAYRFPMGEF

PF00642 // ENSGT00390000018542_0_Domain_5 (1108, 1138)

RLCD-------RLQKGKACPDGDKCRCAHGQEE
LNEWLDRREVLKQKLAKARKDMLLCPRDDDFGKYNFLLQEDGDI----ASATPEVPAAAA
TTTSTAAATTTAE-----------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------MPQRIPVFPGGAP
LLPPVVSVTIPVSSPLPPASFGLVMDPSKKIAS-SMLEAFDSPASS-----LDPLD--PL
D--LLPYTDSHL--EGLDGFGP-VRGSLDTLDSFTLEEPTSQDLRPPSSNAKP-------
-------------------------------L-PAQEPAMPNT----ALLVKNPLASTHF
FKQACHLCYPKT-GPKAGDYTYREDLEHKCKRDILLGRIRNSEDKT-------WKRIRPR
PTKTSFIGSYYLCKDMLNKQDCKYGDNCTFAYHQEEIDVWTEERKGTLNRDLLFDPLGGV
RRGSLTIAKLLKEHQGIFTFLCEICFDSKPRIISKGTKDSPAVCSNLAAKHSFHDNKCLV
HIVRSTALKYSKIRQFQEHFQFDVCRHEVRYGCLREDSCHFAHSFIELKIWLLQQYS-GM
THEDIVQESKKCWQQMEAHASKAANSL-ANSRGPPASAFDLQMKFVCGQCWRNGQVVE-P
DKDLKYCSA--KARHCWTKERRVLLVMSKVKRKWVSVRPLPSIRNFPQQYDLCIHAQNGR
KCQYVGNCSFAHSPEERDMWTFMKD------------NKS------ECV---L---ASWL
-EKAR-GKAGP---V---PGR-----AHRVPVP---QMGFHCWLCGKNSNSKKQWQQHIQ
SEKHKEKVFTSESDSTCWTFRFPMGEF

PF00642 // ENSGT00390000018542_0_Domain_5 (1108, 1138)

RLCER-------FQKKKACPDGDKCRCAHGQEE
LTEWLDRREVLKQKLAKARKDMLLCPMDDDFGKYNFLLQDSDLGRLS---PSPRGPPSVL
TG--DPGR----------------------------------------------------
----------------------

-------------------------------------------MERQKRKADIEKGLQFI
QSTL-PL--KQEEYEAFLLKLVQNLFAEGNDLFREKDYKQALVQYMEGL-NVADYAASDQ
VALPRELLC

PF00515 // ENSGT00390000018542_0_Domain_0 (130, 162)

KLHV--NRAACYFTMGLYEKALEDSEKALGLDSESIRALFRKARALNELGR
HKEAYECSSRCSLALPHDESVTQLGQELAQ------KLGLRVRKAYKRPQ----------
---------------------GTSNGLGSIDDIE-----------------------TDC
YVDPRASPALLPST------------------PTMPLFPHVLDLLAPLDS-SRTLPSTDS
LDDFSDGDVFGPELDTLLDSL-----------SLVQGGLSGSGVPSELPQLIPVFPGGTP
LLPPVVGGSIPVSSPLPPASFGLVMDPSKKLAA-SVLDALDPPGPT-----LDPLD----
---LLPYSETRL--DALDSFGS-TRGSLDKPDSFMEETNSQ--------D--HRPS----
--------S-----G-AQ------------KPAPSPEPCMPNT----ALLIKNPLAATHE
FKQACQLCYPKT-GPRAGDYTYREGLEHKCKRDILLGRLRSSEDQT-------WKRIRPR
PTKTSFVGSYYLCKDMINKQDCKYGDNCTFAYHQEEIDVWTEERKGTLNRDLLFDPLGGV
KRGSLTIAKLLKEHQGIFTFLCEICFDSKPRIISKGTKDSPSVCSNLAAKHSFYNNKCLV
HIVRSTSLKYSKIRQFQEHFQFDVCRHEVRYGCLREDSCHFAHSFIELKVWLLQQYS-GM
THEDIVQESKKYWQQMEAHAGKASS-SMGAPRTHGPSTFDLQMKFVCGQCWRNGQVVE-P
DKDLKYCSA--KARHCWTKERRVLLVMSKAKRKWVSVRPLPSIRNFPQQYDLCIHAQNGR
KCQYVGNCSFAHSPEERDMWTFMKE------------NKI------LDMQQTY---DMWL
-KKHNPGKPGEGTPISSREGEKQIQMPTDYADI---MMGYHCWLCGKNSNSKKQWQQHIQ
SEKHKEKVFTSDSDASGWAFRFPMGEF

PF00642 // ENSGT00390000018542_0_Domain_5 (1108, 1138)

RLCD-------RLQKGKACPDGDKCRCAHGQEE
LNEWLDRREVLKQKLAKARKDMLLCPRDDDFGKYNFLLQEDGDP----AGAT--PEAPAA
AAAAT-----TTGE----------------------------------------------
----------------------

MLLRHFAAMLPFRPLSVLGSAGKCPFLHLHQLGSLLTVVSERLMERQRRKADIEKGLQFI
QSTL-PL--KQEEYEAFLLKLVQNLFAEGNDLFREKDYKQALVQYMEGL-NVADYAASDQ
VALPQELLCK

PF13181 // ENSGT00390000018542_0_Domain_0 (131, 163)

LHV--NRAACYFTMGLYEKALEDSEKALGLDG

ENSGT00390000018542_0_Linker_0_1 (163, 166)

ENI

PF13181 // ENSGT00390000018542_0_Domain_1 (166, 196)

RALFRKARALSELGR
HKEAYECSSRCSLARPHDESVTQLGQELAQ------KLGLRVRKAYKRPQ-ELETFSLLS
N--GTAAGL---------ADQGTSNGLGSIDDIET-----------------------DC
YMDLRGSPAPLPST------------------PTMPLFPHVLDLLAPLDSSSRALPGTES
LDDFSDGDVFGPELDTLLDSL-----------SLVQGGLPGSGVPSELPQLIPVFPGGTP
LLPPVVGGSIPVSSPLPPASFGLVMDPSKKLAA-SVLDALDPPGSA-----LDSLD----
---LLPYSDTRL--DALDSFGS-TRGSLDKPNSFV----------EETKSQDHRPP----
--------S-----G-TQKPAP------------SPEPSMPNT----ALLIKNPLAATHE
FKQACQLCYPKT-GPRAGDYTYREGLEHKCKRDILLGRLRSSEDQT-------WKRIRPR
PTKTSFVGSYYLCKDMINKQDCKYGDNCTFAYHQEEIDVWTEERKGTLNRDLLFDPLGGV
KRGSLTIAKLLKEHQGIFTFLCEICFDSKPRIISKGTKDSPSVCSNLAAKHSFHNNKCLV
HIVRSTSLKYSKIRQFQEHFQFDVCRHEVRYGCLREDSCHFAHSFIELKVWLLQQYS-GM
THEDIVQESKKYWQQTEAHAGKASSSL-GAPRTHGPSTFDLQMKFVCGQCWRNGQVVE-P
DKDLKYCSA--KARHCWTKERRVLLVMSKAKRKWVSVRPLPSIRNFPQ

PF00642 // ENSGT00390000018542_0_Domain_4 (949, 974)

QYDLCIHAQNGR
KCQYVGNCSFAHS

ENSGT00390000018542_0_Linker_4_5 (974, 1108)

PEERDMWTFMKE------------NKI------LDMQQTY---DMWL
-KKHNPGKPGEGTPISSREGEKQIQMPTDYADI---MMGYHCWLCGKNSNSKKQWQQHIQ
SEKHKEKVFTSDSDASGWAYRFPMGEF

PF00642 // ENSGT00390000018542_0_Domain_5 (1108, 1138)

RLCD-------RLQKGKACPDGDKCRCAHGQEE
LTEWLDRREVLKQKLAKARKDMLLCPRDDDFGKYNFLLQEDGNT----AGAAPEAPAAAA
VTGE--------------------------------------------------------
----------------------

-------------------------------------------MERQKRKADIEKGLQFI
QSTL-PL--KQEEYEAFLLKLVQNLFAEGNDLFREKDYKQALVQYMEGL-NVADYAASDQ
VALPRELLCKLHV--NRAACYFTMGLYEKALEDSEKALGLDGESIRALFRKARALNELGR
HKEAYECSSRCSLALPHDENVTQLGQELAQ------KLGLRVRKAYKRPQ-ELETFSLLS
N--GAPAGL---------TDQGTSNGLGSIDDIE-----------------------TDC
YVDLRGSPALLPST------------------PTMPLFPHVLDLLAPLDGSSRTLPGTEG
LDDFSDGDVFGPELDTLLDSL-----------SLVQGGLPASGMPSELPQLIPVFPGGTP
LLPPVVGGSIPVSSPLPPASFGLVMDPSRKLAA-SVLDALDSPGPT-----LDPLD----
---LLPYSEARL--GALDSFGS-ARGSLDKPDSFLEETSSQ--------D--HRPP----
--------S-----S-TQKPAP------------SPEPSMPNT----TLLIKNPLAATHE
FKQACQLCYPKT-GPRAGDYTYREGLEHKCRRDVLLGRLRSSENQI-------WKRIRPR
PTKTSFVGSYYLCKDMINKQDCKYGDNCTFAYHQEEIDVWTEERKGTLNRDLLFDPLGGV
KRGSLTIAKLLKEHQGIFTFLCEICFDSKPRIISKGTKDSPSVCSNLAAKHSFYNNKCLV
HIVRSTSLKYSKIRQFQEHFQFDVCRHEVRYGCLREDSCHFAHSFIELKVWLLQQYS-GM
THEDIVQESKKYWQQMEAHAGKASS-GLGTPRTHGPSTFDLQMKFVCGQCWRNGQVVE-P
DKDLKYCSA--KARHCWTKERRVLLVMSKAKRKWVSVRPLPSIRNFPQ

PF00642 // ENSGT00390000018542_0_Domain_4 (949, 974)

QYDLCIHAQNGR
KCQYVGNCSFAHS

ENSGT00390000018542_0_Linker_4_5 (974, 1108)

PEERDMWTFMKE------------NKI------LDMQQTY---DMWL
-KKHNPGKPGEGTPISSREGEKQIQMPTDYADI---MMGYHCWLCGKNSNSKKQWQQHIQ
SEKHKEKVFTSDSDASGWAYRFPMGEF

PF00642 // ENSGT00390000018542_0_Domain_5 (1108, 1138)

RLCD-------RLQKGKACPDGDKCRCAHGQEE
LNEWLDRREVLKQKLAKARKDMLLCPRDDDFGKYNFLLQEDGDT----TGVTPDAPVAAT
ATAATT---TTGE-----------------------------------------------
----------------------

-------------------------------------------MERQKRKADIEKGLQFI
QSTL-PL--KQEEYEAFLLKLVQNLFAEGNDLFREKDYKQALVQYMEGL-NVADYAASDQ
VALPRELLC

PF00515 // ENSGT00390000018542_0_Domain_0 (130, 161)

KLHV--NRAACYFTMGLYEKALEDSEKALGLDGESIRALFRKARALNELGR
HKEAYECSSRCSLALPHDESVTQLGQELAQ------KLGLRVRKAYKRPQ-ELETFSLLS
N--GTASGV---------ADQGTSNGLGSIDDIET-GSVPERGG-------GEVGPKTDC
YVDLRGSPALLPST------------------PSMPLFPHVLDLLAPLDSSIRALPGTES
LDDFSDGDVFGPELDTLLDSL-----------SLVQGGLPGGGVPSELPQLIPVFPGGTP
LLPPVVGGSIPVSSPLPPASFGLVMDPSKKLAA-SVLDALDPPGPT-----LDPLD----
---LLPYSETRL--DALENFGS-TRSSLDKPDSFLEETNSQ--------D--HHPP----
--------S-----S-TQKPAP------------SPEPSMPNT----ALLIKNPLAATHE
FKQACQLCYPKT-GPRAGDYAYREGLEHKCKRDILLGRLRSSEDQA-------WKRIRPR
PTKTSFVGSYYLCKDMITKQDCKYGDNCTFAYHQEEIDVWTEERKGTLNRDLLFDPLGGV
RRGSLTIAKLLKEHQGIFTFLCEICFDSKPRIISKGTKDSPSVCSNLAAKHSFYNNKCLV
HIVRSTSLKYSKIRQFQEHFQFDVCRHEVRYGCLREDSCHFAHSFIELKVWLLQQYS-GM
THEDIVQESKKYWQQMEAHSGKASS-SLGAPRSHGPSTFDLQMKFVCGQCWRNGQVVE-P
GKDLKYCSA--KARHCWTKERRVLLVMSKAKRKWVSVRPLPSIRNFPQQYDLCIHAQNGR
KCQYVGNCSFAHSPEERDMWTFMKE------------NKI------LDMQQTY---DMWL
-KKHNPGKPGEGTPISSREGEKQIQMPTDYADI---MMGYHCWLCGKNSNSKKQWQQHIQ
SEKHKEKVFTSDSDASGWAFRFPMGEF

PF00642 // ENSGT00390000018542_0_Domain_5 (1108, 1138)

RLCD-------RLQKGKVCPDGDKCRCAHGQEE
LSEWLDRREVLKQKLAKARKDMLLCPRDDDFGRYNFLLREDGDT----TGAT--PEAPAA
AASA--------------------------------------------------------
----------------------

-------------------------------------------MERQRRKADIEKGLQFI
QSTL-PL--KQEEYEAFLLKLVQNLFAEGNDLFREKDYKQALVQYMEGL-NVADYAASDQ
VALPQELLC

PF00515 // ENSGT00390000018542_0_Domain_0 (130, 163)

KLHV--NRAACYFTMGLYEKALEDSEKALGLDGENIRALFRKARALSELGR
HKEAYECSSRCSLARPHDESVTQLGQELAQ------KLGLRVRKAYKRPQ-ELETFSLLS
N--GTAAGV---------ADQGTSNGLGSIDDIET-----------------------DC
YVDLRGSPAPLPST------------------PTMPLFPHVLDLLAPLDSSSRALPGTES
LDDFSDGDVFGPELDTLLDSL-----------SLVQGGLPGSGVPSELPQLIPVFPGGTP
LLPPVVGGSIPVSSPLPPASFGLVMDPSKKLAA-SVLDALDPPGSA-----LDSLD----
---LLPYSDTRL--DALDSFGS-TRGALDKPNSFVGRVTPVSSCPEETNSQDHRPP----
--------S-----G-TQKPAP------------SPEPSMPNT----ALLIKNPLAATHE
FKQACQLCYPKT-GPKAGDYTYREGLEHKCKRDILLGRLRSSEDQT-------WKRIRPR
PTKTSFVGSYYLCKDMINKQDCKYGDNCTFAYHQEEIDVWTEERKGTLNRDLLFDPLGGV
KRGSLTIAKLLKEHQGIFTFLCEICFDSKPRIISKGTKDSPSVCSNLAAKHSFYNNKCLV
HIVRSTSLKYSKIRQFQEHFQFDVCRHEVRYGCLREDSCHFAHSFIELKVWLLQQYS-GM
THEDIVQESKKYWQQMEAHAGKASSGL-GAPRTHGPSTFDLQMKFVCGQCWRNGQVVE-P
DKDLKYCSA--KARHCWTKERRVLLVMSKAKRKWVSVRPLPSIRNFPQQYDLCIHAQNGR
KCQYVGNCSFAHSPEERDMWTFMKE------------NKI------LDMQQTY---DMWL
-KKHNPGKPGEGTPISSREGEKQIQMPTDYADI---MMGYHCWLCGKNSNSKKQWQQHIQ
SEKHKEKVFTSDSDASGWAYRFPMGEF

PF00642 // ENSGT00390000018542_0_Domain_5 (1108, 1138)

RLCD-------RLQKGKACPDGDKCRCAHGQEE
LTEWLDRREVLKQKLAKARKDMLLCPRDDDFGKYNFLLQEDGNP----AGAAPEAPVAAA
VTGE--------------------------------------------------------
----------------------

-------------------------------------------MERQKRKADIEKGLQFI
QSTL-PL--KQEEYEAFLLKLVQNLFAEGNDLFREKDYKQALVQYMEGL-NVADYAASDQ
VALPRELLCK

PF13181 // ENSGT00390000018542_0_Domain_0 (131, 162)

LHV--NRAACYFTMGLYEKALEDSEKALGLDSESIRALFRKARALNELGR
HKEAYECSSRCSLALPHV-TVTQLVKSWPE------TWGLRVRKELETFS-LLSNGTAAG
--------V---------ADQGTSNGLGSIDDIE-----------------------TDC
YVDPRASPALLPST------------------PTMPLFPHVLDLLAPLDS-SRTLPSTDS
LDDFSDGDVFGPELDTLLDSL-----------SLVQGGLSGSGVPSELPQLIPVFPGGTP
LLPPVVGGSIPVSSPLPPASFGLVMDPSKKLAA-SVLDALDPPGPT-----LDPLD----
---LLPYSETRL--DALDSFGS-TRGSLDKPDCFVEETNSQ--------D--HRPP----
--------S-----G-AQKPAPSVMPTVASFLLSQPEPCMPNT----ALLIKNPLAATHE
FKQACQLCYPKT-GPRAGDYTYREGLEHKCKRDILLGRLRSAEDQT-------WKRIRPR
PTKTSFVGSYYLCKDMINKQDCKYGDNCTFAYHQEEIDVWTEERKGTLNRDLLFDPLGGV
KRGSLTIAKLLKEHQGIFTFLCEICFDSKPRIISKGTKDSPSVCSNLAAKHSFYNNKCLV
HIVRSTSLKYSKIRQFQEHFQFDVCRHEVRYGCLREDSCHFAHSFIELKVWLLQQYS-GM
THEDIVQESKKYWQQMEAHAGKASS-SMGAPRTHGPSTFDLQMKFVCGQCWRNGQVVE-P
DKDLKYCSA--KARHCWTKERRVLLVMSKAKRKWVSVRPLPSIRNFPQ

PF00642 // ENSGT00390000018542_0_Domain_4 (949, 974)

QYDLCIHAQNGR
KCQYVGNCSFAHS

ENSGT00390000018542_0_Linker_4_5 (974, 1108)

PEERDMWTFMKE------------NKI------LDMQQTY---DMWL
-KKHNPGKPGEGTPISSREGEKQIQMPTDYADI---MMGYHCWLCGKNSNSKKQWQQHIQ
SEKHKEKVFTSDSDASGWAFRFPMGEF

PF00642 // ENSGT00390000018542_0_Domain_5 (1108, 1138)

RLCD-------RLQKGKACPDGDKCRCAHGQEE
LNEWLDRREVLKQKLAKARKDMLLCPRDDDFGKYNFLLQEDGDP----AGAGAPPEAPAA
AA-AAT----TTGE----------------------------------------------
----------------------

-------------------------------------------MERQKRKADIEKGLQFI
QSTL-PL--KQEEYEAFLLKLVQNLFAEGNDLFREKDYKQALVQYMEGL-NVADYAASDQ
VALPRELLCKLHV--NRAACYFTMGLYDKALEDSEKALGLDGESIRALFRKARSLNELGR
HKEAYECSSRCSLALPHDESVTQLGQELAQ------KLGLRVRKAYKRPQ-ELETFSLLS
N--GTLAGV---------ADQGTLNGLGSIDDIE-----------------------TDC
YVDLRGSPALLPST------------------PTMPLFPHVLDLLAPLDGSSRTLPSTEC
LDDFSDGDVFGPELDTLLDSL-----------SLVQGGLPGSGVPSELPQLIPVFPGGTP
LLPPVVGGSIPVSSPLPPASFGLVMDPSKKLAA-SVLDALDSPGPT-----LDPLD----
---LLPYSETRL--DALDSFGS-AQGSLDKPDSFVEETNSQ--------D--HRPP----
--------S-----S-TQKPAS------------SPEPSMPNT----ALLIKNPLAATHE
FKQACQLCYPKT-GPRAGDYTYREGLEHKCKRDVLLGRLRSSEEQI-------WKRIRPR
PTKTSFVGSYYLCKDMINKQDCKYGDNCTFAYHQEEIDVWTEERKGTLNRDLLFDPLGGV
KRGSLTIAKLLKEHQGIFTFLCEICFDSKPRIISKGTKDSPSVCSNLAAKHSFYNNKCLV
HIVRSTSLKYSKIRQFQEHFQFDVCRHEVRYGCLREDSCHFAHSFIELKVWLLQQYS-GM
THEDIVQESKKYWQQMEAHAGKASS-SLGAPRTHGPSTFDLQMKFVCGQCWRNGQVVE-P
DKDLKYCSA--KARHCWTKERRVLLVMSKAKRKWVSVRPLPSIRNFPQ

PF00642 // ENSGT00390000018542_0_Domain_4 (949, 974)

QYDLCIHAQNGR
KCQYVGNCSFAHS

ENSGT00390000018542_0_Linker_4_5 (974, 1108)

PEERDMWTFMKE------------NKI------LDMQQTY---DMWL
-KKHNPGKPGEGTPISSREGEKQIQMPTDYADI---MMGYHCWLCGKNSNSKKQWQQHIQ
SEKHKEKVFTSDSDTSGWAYRFPMGEF

PF00642 // ENSGT00390000018542_0_Domain_5 (1108, 1138)

RLCD-------RLQKGKACPDGDKCRCAHGQEE
LNEWLDRREVLKQKLAKARKDMLLCPRDDDFGKYNFLLQEDGDT----AGATPEAPVAAT
ATAATT---TGE------------------------------------------------
----------------------

-------------------------------------------MERQKRKADIEKGLQFI
QSTL-PL--KQEEYEAFLLKLVQNLFAEGNDLFREKDHKQALVQYVEGL-NVADYAASDQ
VALPRELL

PF00515 // ENSGT00390000018542_0_Domain_0 (129, 164)

CKLHV--NRAACYFTMGLYEKALEDSEKALGLDGE

ENSGT00390000018542_0_Linker_0_1 (164, 165)

N

PF00515 // ENSGT00390000018542_0_Domain_1 (165, 198)

IRALFRKARALNELGR
HKEAYECSSRCSLALPH

ENSGT00390000018542_0_Linker_1_2 (198, 668)

XXXXXXXXXXXXX------XXXXXXXXXXXXXX-ELETFSPLS
N--GTATGM---------ADQGTSNGLGSIDDIET-GSVPTRGG--------EARALGDC
YVDLRGSPAPLPST------------------PTMPLFPHVLDLLAPLDSSSRALPGTES
LDDFSDGDVFGPELDTLLDSL-----------SLVQSGLPGSGLHSELPQLIPVFPGGTP
LLPPVVGGTVPVSSPLPPASFGLVMDSSKKLAA-SMLDALDPPGSA-----LDSLD----
---LLPYSETRL--DALDSFGS-TRSSLDKPDSFSVXXXXXXXXXXXXXXXXXXXX----
--------XXXXX--------X-------------------XX----XXXXXXXXXXXXX
XXXXXXXXXXXX-XPRAGDYTYREGLEHKCKRDILLGRLRSAEDQT-------WKRIRPR
PTKTSFV

PF00642 // ENSGT00390000018542_0_Domain_2 (668, 694)

GSYYLCKDMINKQDCKYGDNCTFAYH

ENSGT00390000018542_0_Linker_2_3 (694, 800)

QEEIDVWTEERKGTLNRDLLFDPLGGV
KRGSLTIAKLLKEHQGIFTFLCEXXXXXXPRIISKGTKESPSVCSNLAAKHSFYNNKCLV
HIVRSTSLKYSKIRQFQEH

PF00642 // ENSGT00390000018542_0_Domain_3 (800, 825)

FQFDVCRHEVRYGCLREDSCHFAHS

ENSGT00390000018542_0_Linker_3_4 (825, 948)

FIELKVWLLQQYS-GM
THEDIVQESKKYWQQMEAHVGKGSS-SLGAPRTHGPGTFDLQMKFVCGQCWRNGQVVE-P
DKDLKYCSA--KARHCWTKERRVLLVMSKAKRKWVSVRPLPSIRNFP

PF00642 // ENSGT00390000018542_0_Domain_4 (948, 974)

QQYDLCIHAQNGR
KCQYVGNCSFAHS

ENSGT00390000018542_0_Linker_4_5 (974, 1105)

PEERDMWTFMKE------------NKI------LDMQQTY---DMWL
-KKPNPGTPGEGTPLSPREGEKQIQMPTDYADL---MMGYHCWLCGKNSNSKKQWQQHIQ
SEKHKEKVFTSDSDASGWAYRFPM

PF00642 // ENSGT00390000018542_0_Domain_5 (1105, 1138)

GEFRLCD-------RLQKGRACPDGDKCRCAHGQEE
LNEWLDRREVLKQKLAKARKDMLLCPRDDDFGKYNFLLQEAGDTAPP------EAPAATT
AATTTTRE----------------------------------------------------
----------------------

-------------------------------------------MERQKRKADIEKGLQFI
QSTL-PL--KQEEYEAFLLKLVQNLFAEGNDLFREKDYKQALVQYMEGL-NVADYAASDQ
VALPRELLCK

PF13181 // ENSGT00390000018542_0_Domain_0 (131, 162)

LYV--NRAACYFTMGLYEKALEDSEKALGLDSESIRALYRKARALNELGR
HKEAYECSSRCSLALPHDENVTQLGQELAQ------KLGLRVRKAYKRPQ-ELETFSLLS
N--GTPAGM---------TDQGTSNGLGSIDDIE-----------------------TDC
YVDLRGSPALLPST------------------PTMPLFPHVLDLLAPLDGSSRTLPITEG
LDDFSDGDVFGPELDTLLDSL-----------SLVQGGLSGSGVPSELPQLIPVFPGGTP
LLPPVVGGSIPVSSPLPPASFGLVMDPSRKLAA-SVLDALDSPGPT-----LDPLD----
---LLPYSEARL--DALDSFGS-ARGSLDKPDAFIEETSSQ--------D--HRPP----
--------S-----S-TQKPAP------------SPEPSMPNT----ALLIKNPLAATHE
FKQACQLCYPKT-GPRAGDYTYREGLEHKCKRDVLLGRLRSSEDQI-------WKRIRPR
PTKTSFVGSYYLCKDMINKQDCKYGDNCTFAYHQEEIDVWTEERKGTLNRDLLFDPLGGV
KRGSLTIAKLLKEHQGIFTFLCEICFDSKPRIISKGTKDSPSVCSNLAAKHSFYNNKCLV
HIVRSTSLKYSKIRQFQEHFQFDVCRHEVRYGCLREDSCHFAHSFIELKVWLLQQYS-GM
THEDIVQESKKYWQQMEAHAGKASS-SLGAPRTHGPSTFDLQMKFVCGQCWRNGQVVE-P
DKDLKYCSA--KARHCWTKERRVLLVMSKAKRKWVSVRPLPSIRNFPQ

PF00642 // ENSGT00390000018542_0_Domain_4 (949, 974)

QYDLCIHAQNGR
KCQYVGNCSFAHS

ENSGT00390000018542_0_Linker_4_5 (974, 1108)

PEERDMWTFMKE------------NKI------LDMQQTY---DMWL
-KKHNPGKPGEGTPISSREGEKQIQMPTDYADI---MMGYHCWLCGKNSNSKKQWQQHIQ
SEKHKEKVFTSDSDASGWAYRFPMGEF

PF00642 // ENSGT00390000018542_0_Domain_5 (1108, 1138)

RLCD-------RLQKGKACPDGDKCRCAHGQEE
LNEWLDRREVLKQKLAKARKDMLLCPRDDDFGKYNFLLQEDGDT----TAATPEAPIAAT
ATAATT---TTTGE----------------------------------------------
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