ENSGT00390000017457_0 : Linker Region Query Results

---------------------------------------------------------MGS
RDPAEPMSPGEATQSGARPADRHGLLKHSREFLDFFWDIAKPEQETRLEATEKLLEYLRG
RPKGS-EMKYALKRLITGLGVGRETARPCYSLALAQLLQSFEDLPLCSILQQIQEKYDLH
QVKKATLRPALFANLFGVLALFQSGRLVKDQEALMKSVKLLQALAQYQNHLQEQPRKALV
DVLSEVSKATLQEILPEVLK-ADLNIILSSPERLELFLLAQQKVP-----SKLKKLVGSV
NLFSDENLPAIA--------------------LDCCAWRLRKISSHGSGR-RVVEQGLLK
MQFWPASYLCFRLLGAALPLLTKEQLQLVMRGDVIRHYGEHVCTAKLPKQFKFAPEMDDY
VGTFLEGCQDDPERQLAVLVAFSSVTNQGLPVTPTFWRVVRFLS--PPAL----------
--QGYVAWLRAMFLQPDLDSLVDFSTNNQKKAQDSSL-----HVPERAVFRLRKWIIFRL
VSI-VDSLHLEMEEALTEQVARFCLFHSFFVTKKPTSQIPETKGPFSFPLESQAREAVSS
AFFSLLQTLSTQ-------------FKQAPDQTRGGQPWTYHLVQFADLLLNHSH-NVTT
VTPF-TEQQRQAWDRMLQTLKELEAHSSEA-R--AAAFQHLLLLVGIHLLKA------PF
SSGKWRPLAK----AGRGLERR-A------------------------------------
---GAA--------NGSLAGTPPQVLNPETSEDED-DRVVVMDDSAERRLKGA-----ED
KSED-----GEDNRSSESEEESE--GEESEEEERDGD-VDQGFREQLMTVLQAGKALGGE
DSEDE----EELGDEAMMALDQSLASLFAEQKLRIQARRDEKNKLQKEKALRR-DFQI-V
LDLVEVLVTKQPENALVLELLEPLLNIIRRSLRSS----SSKQE---QDLLHKTARIFTH
HLCRARRYCHDLGERAEALHAQVERLVQHAGRQPDSPTALYHFNASLYLLRILKGNTAHG
CVHETQEKQKAGTDPS---------------------------------------LMPMG
PQ--GPTLSLLK------AASCLDLNLVTRVYSTALSSFLTKRNSPLTVPMFLSLFSRH-
------------------------------PVLCKSLLPIPV-------QHITGPVRPRH
Q--ACLLLQKSLSMREVRSC----FEEPEWKQLMGQVLAKVTEN----------------
--------------------------LRVLGEARTKAEHQQALSSLELLNALF---RTCK
HEKLTLDLTVLLGVLQGQQQ-------SLQQGAHS--TGSSRLHDL-----YWQAMKTLG
VQR-----------------------PKLEK-DAKE-VPSATQSPISKKRKKKGFLPETK
KRKKRKSEDGTSAE-----------DGTPAATGGSQP--PSMGRKKRNRT--KA------
------------------------------------------------------------
----------------------KVPAQAQANVTPS-TKSPAPGAP---------------
----------------------------------------------------TLSPSTP-
AKFPKLQKKNQKLLQVNGA-PGS---PAEPAGQKQHQKALPKKGVLGKSPL---SALARK
KAR--LSLVIRSPSLLQSGAKKKK--TLRF--TISSSKN

----------------------------------------------LKLEP---------
-----AEAAAAEDAGRRSACAADSFLQQSRDFLDLFWGIAKPAQDERLAATAALVERLRT
RPQXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
--XX-XXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXX-XXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXKKEKVLPPGALDLMRIALQEGTFELFWK-GVVEDGLLQ
EHSGPSSYTAFRLLGSALPLLSLEQLHMVLHGEVMLRYGDHVLSAQLPSRFKFAPEMEKY
VGSFLEGC-TDPEKQLAVLVAFSSLTNQGYPVVPSLWSVVRHLR--PEVL----------
--HRYSSWLQDMFLRPDLSCCLDFSTSRQKXXXXXXXXXX-------------XXXXXXL
TSI-VENPQVTKDEAFIMGIARFCFFHSFFETKKLSKDVPESEQQISVPLDSESRDISGN
AFFRLGEAPKAA--------LSLPKGKAGHGVMADGQLWIQHLVQYADFLLSHSK-NVQL
VKPF-SAEEKAAWDRMLQSTELLQQREA---EAEIMAFQQLLLLVGIHLFKX------XX
XXXXXXXXXXXXXXXXXXXXXXX---XXXXXXXAEEPPRGGEVMVEILLALLSQPSRLMR
QVCRGVFTRVCPHLNRKALQLILDAGEVENRH-GMSGPGDESEE--------D-----LD
GDED--EGRSDDS--E-------ASEDEDQASASDEE-VDGGFRQQLMNVLQAGKALDA-
DGESS---EEELDDDAMMALDARLSSLFAEQKLRAQAKRREKDAVQKEKNLRC-DFKIKV
LDLVEGFLTKQPENPLVLELVEPLLAVIERSMSRN----SAKQE---QDFLRKTADIFTN
QLCRAKQYCHSVADRAEDLHAMLERLVQQAGRQVDSAVALYHFSASLYLLRVLKGNTAKG
SPVPKKQRKV--------------------------------------------------
------------SVLPKEGSSCLDLARVTHLYTEALTSFLSKRNSPFTAAMFVDLFTRH-
------------------------------PMICQQLVPVIL-------PFITTGVRPY-
-HQACLMLLKALQMRELKQA----LEGPAWRELMGQRQT--TES----------------
--------------------------LRIVGKAT---KKPPQFKALELLVFLI---RTVK
EEXXXXXXXXXXXXXXXXXX---------XXXXXXXXXXXXXXXXX-----XXXXXXXXX
XXR-----------------------PKEDKVEPL----RARMWPFRETQRKKGFLPETK
KRKRRQGACSEGGKERPA------------A--TATSHHHSAGKRKRKRRRAKVPGPQVN
-GT----------------------TEGPTFGAPALKPARPRLVN---------------
----------------------------RASGSPAPGSEEQ-------------------
------------------------------------------------------------
-------------------------------------KGLPRKGVLDAAPP---ATSLEK
KAK--LPPTV-GS-WPQGPAAK--------------E--

---------------------------------------------------------MGS
REPAEPLSSGDATQNSARPADRHGLLKHSREFLDFFWDIVKPEQETRLAATEKLLEYLRA
RPKGS-EMKYALKRLITGLGVGRETARPCYSLALAQLLQSFEDLPLCSILQQMQEKYDLH
QVKKSMVRPALFANLFGVLALFQSGRLVKDQEALRKSVKLLQALAQYQNHLQEQPWKALV
DILSEVSEATLEEMLPEVLS-TDLDAMFSCPEQLGLFLLAQQKVP-----SRLKKLVGSI
NLFSDENVPRLVNVLKMAASSVKKERKLPTVALELLHLALKENEFLRFWK-GVVEQGLLK
LQFWPASYLCFRLLGAALPLLTKEQLQLVMRGDVIRHYGEHTCTAKLPDQFKFATEMEEY
VGTFLEGCRDDPERQLAVLVAFSSATNHGLPVVPTFWRVVRFLS--PQAL----------
--QGYVAWLQGMFLQPDLDSLIDLSTDNPKKAQDASQ-----HMPKRAVFRLRKWIILRL
VSL-VDNLYLEMEEALTEEVARFCLFHSFFVTKKPTSQIPETRQQLSFPLESQAREAVSS
AFFSLLQTLSTQ-------------FKLAPEQTRGGQPWTYRLVQFADLLLNHSH-SVSL
VTPL-TAQQCQAWDRMLQTLKELEAPSSEP-R--AAAFQHLLLLVGIHLFKS------PT
ESCDLLGDIQTCIRKSLGERCR-GSRT---KVIDPQELPWVEVLVEILLALLAQPSHLMR
QVARSVFGHVCSHLTPRALQLILDVLSPETSEDVD-DHVVVTDESDERWLKAA-----ED
KSED-----GEENRGSESEDQSD--GGESEEEERDRD-VDQGFREQLMSVLQAGKALSGE
ESEDE----EELGDEAMMALDQSLASLFAEQKLRIQARRDEKSKLQKEKALRR-DFQIRV
LDLVEVLVTKQPENVLVLELLEPLLGIIRRSLCSS----SSKQE---QDLLHKTARIFTH
HLCRGRRYCHDLGDRVEALHGQVARLVEQAGRQPDSSTALYHFNASLYLLRVLKGGTAKG
HVHETQEVLEAGTDPS---------------------------------------PSTEG
L----------------QAAGCLDLNLTIRIYSSALSSFLTKRHSPLTVPMFLSLFSRH-
------------------------------PVLCKSLLPILV-------QRVTGPGRPRQ
QAQACLLLQKTLSMREVRLC----FQDPEWKQLIGQVLTKVTEN----------------
--------------------------LRTLGEVQTKAEHQQALSSLELLNTVF---RTCK
HEKLTLDLTVLLGVLQGQQQ-------GLQQGVHS--TGSSRLLDL-----YWQAMKTLG
VQR-----------------------PKLEK-NPKE-IPSATQGPISRKRKKKGFLPETK
KRKKHRSE-----------------DDMPAATGGSQP--PGTGRK-RKRM--KA------
------------------------------------------------------------
----------------------KVPAQ--ANGTPT-TKGPAPGTP---------------
----------------------------------------------------TLSPNTP-
AKFPKLQKKKQKLSWVNGA-PSS---PTKPAGQKQHHKALPKKGVLDKSPL---STLARN
KAR--PPLVIRSLSLLQSGTKKK-AQTLRF--TISSSKK

---------------------------------------------------------MES
RDPAEPMSPGEATQSGARPADRYGLLKHSREFLDFFWDIAKPEQETRLAATEKLLEYLRG
RPKGS-EMKYALKRLITGLGVGRETARPCYSLALAQLLQSFEDLPLCSILQQIQEKYDLH
QVKKAMLRPALFANLFGVLALFQSGRLVKDQEALMKSVKLLQALAQYQNHLQEQPRKALV
DILSEVSKATLQEILPEVLK-ADLNIILSSPEQLELFLLAQQKVP-----SKLKKLVGSV
NLFSDENVPRLVNVLKMAASSVKKDRKLPAIALDLLRLALKEDKFPRFWK-EVVEQGLLK
MQFWPASYLCFRLLGAALPLLTKEQLHLVMQGDVIRHYGEHVCTAKLPKQFKFAPEMDDY
VGTFLEGCQDDPERQLAVLVAFSSVTNQGLPVTPTFWRVVRFLS--PPAL----------
--RGYVAWLRAMFLQPDLDSLVDFSTNNQKKAQDSSL-----HMPERAVFRLRKWIIFRL
VSI-VDSLHLEMEEALTEQVARFCLFHSFFVTKKPTSQIPETKHPFSFPLENQAREAVSS
AFFSLLQTLSTQ-------------FKQAPGQTQGGQPWTYHLVQFADLLLNHSH-NVTT
VTPF-TAQQRQAWDRMLQTLKELEAHSAEA-R--AAAFQHLLLLVGIHLLKS------PA
ESCDLLGDIQTCIRKSLGEKPR-RSRT---KTIDPQEPPWVEVLVEILLALLAQPSHLMR
QVARSVFGHICSHLTPRALQLILDVLNPETSEDEN-DRVVVTDDSDERRLKGA-----ED
KSEE-----GEDNRSSESEEESE--GEESEEEERDGDV-DQGFREQLMTVLQAGKALGGE
DSENE----EELGDEAMMALDQSLASLFAEQKLRIQARRDEKNKLQKEKALRR-DFQIRV
LDLVEVLVTKQPENALVLELLEPLLSIIRRSLRSS----SSKQE---QDLLHKTARIFTH
HLCRARRYCHDLGERAEALHAQVERLVQQAGRQPDSPTALYHFNASLYLLRVLKGNTAEG
CVHETQEKQKASTDPS---------------------------------------PMPTG
PQ--GPTL---SPLM--KAASCLDLNLVTRVYSTALSSFLTKRNSPLTVPMFLSLFSRH-
------------------------------PVLCQSLFPILV-------QHITGPVRPRH
Q--ACLLLQKTLSMREVRSC----FEDPEWKQLMGQVLAKVTEN----------------
--------------------------LRVLGEAQTKAQHQQALSSLELLNVLF---RTCK
HEKLTLDLTVLLGVLQGQQQ-------SLQQGAHS--TGSSRLHDL-----YWQAMKTLG
VQR-----------------------PKLEKKDAKE-VPSATHSPISKKRKKKGFLPETK
KRKKRKSEDGTPAE-----------DGTPAATGGSQP--PSMGRKKRNRT--KA------
------------------------------------------------------------
----------------------KVPAQ--ANGTPT-TKSPAPGAP---------------
----------------------------------------------------TLSPSTP-
AKYPKLQKKNQKPSQVNGA-PGS---PTEPAGQKQHEKALPKKGVLGKSPL---SALARK
KAR--LSLVIRSPSLLQSGAKKKK-VQLRK--AGKP---

------------------------------------------------------------
------MAEREARHGGGVPADPRGVLRKGRAFLDLFWDIAKPEQEVRLAATENLLRHLRD
GGEDE-ELKYALRRLVEGLGATREAARPGFSLALAQVLQAFEEIPLCSVLEQIQEKHNLE
KVKKKLVRNAAFGNFFGVMALFQSGRLIKDQKALLESIQLLQQLAHHQTHLRDLPSKTLV
DILSEVPETVFEEVLFGILQ-ADLTSAFKSPENLHLLLVGMQKFPGVLKPKKLKKLFGSP
TIVNEENIPRLVELLESAAKSEKKDKKLPSVGLDLLQVSLKEGAFELFWS-EAVENGLFK
EKSGPVSYMCYRLLGSALPLLSVDQLQMVLKGRVMQHYGEHVVTTQLPDRFKFAPEMEAY
VDKFLTSC-DDPERQLAVMIGFSTLTNQGYPVVPSVWRVVRHLQ--PVAL----------
--QKYIDWLKDMFLKPDLGCCLDFSTNRQKQNQENK------NIAQHKIARLRKWIIHRL
MSI-VESP-VKKEESLVMDISRFCFFHAFFETKKKTSQIPETNALMSEPLDEQAHSLAAN
YFFGLLQTLNTLTVLGDTAEAAALREKHIHGVTADGKLWIFHLVEYASELLSSEK-YVKA
VKPF-TKEQRDAWERSLQSVKNLQKKKSKSDSAKLFAFQQLLLLMAIHLFKN------PS
ETMDLLSDLLNCTERAFSKEPKKK-----KT--ENAEPEWVEVIVEILLSLLAQPSLLIR
RISNSVFGRICPNLTKKGLQLILDVLDPYQDQDEESAVVVVEES-EKEKKSAQ------D
T--D--DDESEDS--SDDGDTEE--ENDS-EDEKNEE-VDEDFRSQLINVLQAGNAV---
GEDES---DEELDDEAMMALDKSISALFAEQQKRIQAKKDEKDRIRKEKILRR-DFKIKV
LDLIEVFLSKQPENPLVFDIIEPLLQVIEQCMSSD----SDKQE---IDFLQKTAHIFTN
SLCRAKQYCKRVDVLQDDLHTFVERLVKKACKHTDSSVALYYFSASLYLLKVLKGNVSDK
SPALPVPLSK---KQTD-------------------------------------------
---------TIPQACQLLSTGCLDVERVTLIYQQALTQFLSKRNSALTSSMFLDLFTRF-
------------------------------PVSGAALWCTSFWWLQNTAVSLGKGEKLFH
FVVGC-------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
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------------------------------------------------------------
---------------------------------------

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------------------------------------------------------------
------------------------------------------------------------
----------------------FCFFHAFFETKKPTADIPETERQLSVPLDEQTREVIAN
SFFSLLQNLNNL-------------LKHVQGVTLDGRLWIQCLVQFADFLLSHGR-NVKA
VRPF-TADQKEAWDRMLKSAGELQKQDDEAWGAESSAFQLLLLLVGIHLFKS------PL
ECVELLGDLHGCIEKALDKKTKKAQAG--TKG-AAAEPGWVDVVVEILLSLLAQPSRLMR
QVARSVFARICPHLSRSALQLILDVLDPDQNQDGEEGPVVVTEESSEKAAVAK-----K-
--DR--HEAGSDS--SDDDSSGT----ESEDEARDAD-VDEDFRKQLMNVLHAGKMP-VG
DGDGS---DEELSDQAMMALDKNLSSLFAXXXXPPDHRLPGG---RASNPPKGQERDGEV
LDLVEVVLVKQADNPLVLELIEPLLTVIERSMSSD----AGKQE---QEFLRKTAYIFTN
QLCRAKQYCRSVGARHGELHELLRRLVLRACRQSDSSVALYCFNASLYLLRVLKGNVSDQ
PPAATPAKTEKAKKAAQ----LSPAH----------------------------------
--------LPTHPAAAALSMGCLDLPKVTELYRMALNLFLTKRHSPLTMPMFADLFGRH-
------------------------------PV----------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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---------------------------------------

---------------------------------------------------------MES
EVLAEAVAPGEAPKGGAPVSDPHGLLQHSREFLDFFWDIARPEQETRLAATEKLLEYLRA
RPQGS-EIKYALKRLVTGLGSVRETARPCYSLALAQXXXXXXXXXXXXXXXXIQ-EYDLS
MV-----RA--LA-HLLRLALFQSGRLVKDQEALMKSVKVLQVLAHHRNHLQEQPQKALV
DILTEVPEATLKEILPKVLK-DNLTMVLSSPESLELFLLARQKVP-----ARLEKLLGPV
DLFSDENIPKLVDVLKVAASSVKKERKLPAVALGLLRLALQENKFPRFWN-EVLEQGLLK
KQFPPASFLCFRLLGAALPLLSEKQLQLALRGAVAQQYGEHLVIAKXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXX----------
--XXXXXXXXXXXXXPTLDSLVDFSTRNQKKHQNASV-----NSPERAVYRLRKWIILRL
VSI-VENSQVEKEAALVQEVARFCLFHSFFETKKPTSQIPETEQKISFPLESRTREMVCS
AFFSLLQALSTQ-------------FKQVQSQS-PGQPWIYHLVQFADNLL-KSR-NVVP
MTPF-TEQQRQAWDRMLQTHKELEARSSEA-K--ATAFQHLLLLVGIHLFKT------PA
ESCSDLADIQACIQKSLGGKPR-RTRS---KAADAQEPPWVEVMVEILLALLAQTSHLMR
QVARSVFGHICSHLTPRALQLILDVLNPDKVQDEE-DSVVVTDDADEKQRKTK-----AP
KNGS------EDGS-EGGGGEEEEEEEESDEEARDDD-VDQGFREQLMAVLQAGKALGGE
DSED-----EELGDEAMMALDQNLASLFAEQKLRMQAKQDEKNRLQKEKTLRR-DFQIKV
LDLIEVLVSKHPESPLALELIEPLLTIIRRSMRTS----SSKQE---QDLLHKTARIFTH
HLCRNRHYCHDIGNHVQALHAQVERLVQQAGHQADSSVALYYFNASLYVLRVLKGNTACP
-AHKTPKKQKAKA---------------------------------------------TV
PE----------------ATSCLDLKRVTPVYSSALSAFLTKRNSPLSIPMFLSLFYRH-
------------------------------PVLCKNLLPVMM-------QHVTGPTRPRQ
QXXXXXXXXXXXXXXXXXX------XXXXXXXXXXXXXXXXXXN----------------
--------------------------LCTLGKAQAKAEQQGELAALELLIILL---KAIH
YQKLTVDLTPILTLLQGLQP---TLQQSLQQGAHP--AGSSRLYDL-----YWQAMKLLG
VQR-----------------------PKSEKKDAKE-NPSDSQGPISMKRKKKGFLPETK
KRKKRKPEEAAEPA------------AKQAADGENQPPTPSSGKKRRRRHRAKS------
------------------------------------------------------------
----------------------KASAQSQASGEPA-TKGPAPATP---------------
----------------------------------------------------TASSSTP-
AKTPKLQKKRQKLSQVNGDAPTE---P---AGKKL------QEGVPDKSPQ---PTPPRK
KTKLPLANGSPSPSVLRSGTKRNTQTLR---FTISSSRK

------------------------------------------------------------
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--------MCYRLLGSALPLLSLDQLPIVLRGEVMRHYGEHVVSAQLPDRFKFAPEMETY
VDSFLEGC-DDPEKQLAVMVGFSTLTNQGYPVVPSFWKVVKHLQ--PETL----------
--LKYVNWLKRMFLRPDFDCCLDFTTSRQKQNQEKA------NLTQHRVLRLRKWIIARL
VSI-IDSQ-GKKEEDLVMDIVRFCFFHAFFETKKPTSEIPETESLPSVPLDGQSHSTVAN
LFFSLLQILNNLPVLGDTAEAAALREKHVHGVTADRSLWLYLILQYASTLLSHGK-HVKA
VTPF-TAEQRAAWDRMLQSLENLQKKD-KSHNMEIVAFQHLLLLVGIHLFKT------PA
ETLDLLNDLLNCIERAFDKKSK-------KA--DDEEPEWVEVIVEILLSLLSQPSLLMR
RVSKSVFGRICPYMSKKALHLILDVLDPEQDQDEECAVVVMEET-DKKKKSSG------A
N-MD--EEESADS--SDDNSSAEDGEEDSEDENNTDD-VDENFRNQLMNVLQAGNAL---
GGDQS---DDDVDDETMLALDENISALFAEQQKRIQAKKDEKEKMRKEKILRR-DFKIKV
LDLVEVFLAKQPESPLVFDIIEALLLVIEQSMSSD----ADKQE---QDFLQKTADIFKN
RLCRAKQYCKSVGDHQADLHAQLESLVKRASKHTDSPVALYYFSASLYLFKVLKGNMARE
EAATLSSSKKKQKNNKE-------------------------------------------
---------NSAQTDQLSDTGLLDLKRVTTVYQEALSGFLTKRKSALTAAMFLDLLARF-
------------------------------PVMCKPLIGTLV-------KSITAGARQHQ
QAQACVLLQKALQTRDLKLS----MTEEEWGELIKESTSQITES----------------
--------------------------LKAVNQFKVKVDQEKVIKCLELLNFLI---KTAN
QQKLTVELAELSRVLQALSQ---------QEGF----GKSGRLSNL-----YWNVMNLLG
FAR-----------------------PKREKAEPQ---PEHAPGAEPLKRKKKGFLPASK
KRKNRKKAPAEPPEGGAE------------SSKEAG----AAGG----------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------EAAAHNSRKRKGAAGKAGG---ESPWPK
KAK--GSPGKETP-GKQGKARRKKK-KKAKQTPAPTA--

------------------------------------------------------MAEMKN
LETAEPGSSGGAT-----QADRHGLLEHSREFLDFFWDIAKPEQETRLQATEKLLQYLRT
RPE-GSEMKYALKRLITGLGVGREAARPCYSLALAQLLQSFEDIPLCSILKQIQEKYELQ
KVKKAMMRPALFANLFGVLALFQSGRLVKDREALMKSVRLLQILSHHYNHLQGQPMKVLV
DILTEVPEAMFEEILPKVLR-GDLKVVLGSPKHLELFLLAQRRVP-----AKLKSLMGAV
DLFTEENIPSLVNVLKMAAMLVKKEQKLPELALGLLQLALKENKFPQFWK-EVVEQELLK
KPSWPTSYLCFRLLGAALPLLSEEQLQLVMRGELIRHFGEHIVVAKPPNQFKFVPEMSVY
VSTFLEGCQDDPGRQLAVLVAFSSITNQGLPVMPTFWRVTRFLS--PEAL----------
--RSYVAWLWDMFLQPRLDSLVDFSTANQKKTQDASV-----NVPERCVFRLRKWIIHRL
VSL-VDQLHLEKDEDLIEQVARFCLFHAFFKTKKATGQIPETKQHFSFPLDGRTREVIVS
TFFSLLQTLNPK-------------FKQTADQSEGAKPWTYRLVKLADMLLNHSR-NVVV
VTPF-TAQQRQAWNQMMDTLKELEARSSEI-K--ATAFQHLLLLVGLHLFKS------PA
EIYDLLNDIQTCIKKSVEQKPR-RSRS---RANTSQEPPWVEVMVEILLSLLAQPSHLIR
QVARNVFGHICSHLTPRALQLILAVLNPETE--ED-DNVVVTDDSSEKQPKET-----ED
EGED-----SEDSKDSKSEGES-EDEEESEEEERDGD-VDPGFRQQLMAVLQAGKALGGV
DSED---DEEELGDEAMLALDQNLASLFAEQKLRIQARREEKNKLQKEKILRR-DFQIRV
LDLIEVLVTKQPENPLVLELLEPLLNIIQRSMRSSG---TTKQE---QDLLHKTARIFMH
DVCRARHYCHNVEHCTEALHTQVERLVQQAGRQADSSVALYYFNASLYLLRVLKGNISKS
HQ-QGDNTE-----LE---------------------------------------P--MD
Q---------------E-TANCLDLSFVTLVYSEALSSFLTKRNSPLTVPMFLSLFSRY-
------------------------------PVSAGPRYH---------------------
------LMIPLLGPRELRVC----FEDPEWEQLISQVLAKVTQT----------------
--------------------------LRTLGEAQSKSEHQKELSSLELLNTVF---KIIN
HEKLSVDVTTLLGVLQSQQQ---KLQQSLQQGNHS--SGSSRLYDL-----YWQAMKMLG
IQ-----------------------RPKLEKKDDKDVVPSDIQSPVSMKRKKKGFLPETK
KRKKRKAEDAVPQQ-----------DAMPVATSGDQPPST--GKKRKKM-KAQVVAQTQL
NGTPA-------------------------------------------------------
------------------------------------TKSPAPDSA---------------
----------------------------------------------------TQSPSTP-
AKTPKLQKKKEQLSQVNGATPVS---PTQLSGKKQRRKSLAQKGVLSKS---PQSALPRK
KSR--LSLVSRSPSLLQSGTKRKKMARRKEQTP------

------------------------------------------------------MAEMES
QDVAEPMAPGEASKSGARPADREGLLKHSREFLDFFWDIAKPQQETRLEATEKLLEYLRA
RPQGA-EMKYALKRLITGLGVGRETARPCYSLALAQLLQSFEDIPLCSILQQIQEKHDLQ
KVKKATMRPALFANLFGVLALFQSGRLVKDSEALMKSVKLLQTLAQHHNHLQEQPQKALV
DILSEVPEATLQEILPKVLR-ADLNSVLGSPEHLELFLLARQKVP-----RKLEELVGPV
SLFSDENVPRLVSVLKMAAASVKKERKLPAVALDLLRLALQEGKFPRFWK-DVVEQGLLK
KQSWPASYLCFRLLGAALPLLSAEQLPLVMRGDLIRHFGEHMVTAKLPNQFKFAPEMNEY
VGAFLESCRADPERQLAVVVAFTSVTNQGLPVLPTFWRAVRFLS--PPAL----------
--KGYVAWLRTMFLQPDLDSLVDFSTSNQKKAQDASL-----HVPERAVSRLRKWLILRL
VSI-VDTLHVEKEEDVIEEVARFCFFHSFFEAKKPTSQIPETEQRFSFPLESRTREVVGS
AFFSLLQTLSTQ-------------CRQAPEQTQDSQPWTYRLVRFADSLLNHSR-NVAA
LTPF-TAQQRQAWDRMLQSVRELEATSSGA-GAKAAAFQHLLLLVGIYLFKS------PT
ESCDLLGDIQTCIKKSLGEKTR-RTRS---KATNPQEPPWVEVLVEILLALLAQPSHLMR
QVARSVFSHICSHLTPRALQLILDVLNPEKNADED--SVVVTDGSE-EQLEGA-----ED
RSSD-----GEDDRASAGEEDSGEDSDDSEEEDRDAD-VDQGFREQLMAVLRAGKALGTV
DGEDDDDDGDELGDEAMMALDQNLASLFAEQKLRIQARKDEKDKLRKEKVLRR-DFQIRV
LDLIEVLVTKQPESPLVLELLEPLLDVIRRSMRTS----STKQE---QDLLHKTARIFTH
HLCRSRHYCHDVGRLVGTLYAQVERLVQQAGRQADAAVSLYYFNAALYLLRVLKGNAAGK
PVCKAPKKEKAGS-------------------------------------------QPKG
PE--VA-----------QAAGGLDLSLVTPIYSSALTSFLTRRNSPLTVTMFLSLFSRH-
------------------------------PVLCKSLLPVVI-------QHVTGPARPRH
QAQACLLLQKALPTRELRVC----FDDPEWEQLVSQILAKVTEN----------------
--------------------------LRTLGEAQTKSEHQKELSSLGLLNTLF---RTIH
QEKLTVDLTAVLGVLQSKQQ-------SLQQRECA--AGSSRLYDL-----YWQAMKALG
VQ-R----------------------PKSAKKEAKE-VPSVTQNPVSTKRKKKGFLPETK
KRKKPKSEGPAPEE-----------GARPAATGEQQP--PSTGKKRRHRR--KA------
------------------------------------------------------------
----------------------TVPAQAQAQAKQRPAPDPAAAAA---------------
----------------------------------------------------ITGPGTP-
AKTPKLK-KKRKLSQVNGAAPVS---PVEPAGKKQPQKDLPEKGVSGKSPQ---SALPRK
KAR--LSLASRSPSLLQSGAKRKKAQLRKARKP------

---------------------------------------------------------MES
VDGAETKPSKEKMKNGHRPADRQGLLKHSREFLDFFWDIAKPQQETRLEATEKLLEYLRT
RPKGS-EMKYALKRLITGLGVGRETARPCYSLALAQLLQSFEDIPLCSILEQIQEKHNLQ
KVKKTMMRPALFGNLFGVLALFQSGRLVKDPEALLKSVQLLQTLAEHSNHLQEQPQKALV
DILSECPLSTL-EILPKLTD--GLNSVLSS-HELALFLLAREKVP-----VKLKKLMGLV
DLFSAENIPRLIGVLKTAATSTRKELQLPDVVLNLLRLALREDKFPQFWN-DVIDQGLMK
KRCWPANYMCFRLLGAALPLLSTEQLQLAMQGDLIRVLGEHVLTSQGPGKYRFAPEMTKY
VNTFLEGCREDPERQLAAMVAFTSVTNHGQPVTSTSWRVVESLS--VPAL----------
--RAYAAWLRDMXXXXXXXXXXXXXXXXXXXXXXXXX-----XXPEYHVLRLRKWIIFRL
VNL-VGNLHVEKEEALVEEVVRFCFFHAFFETKKPEPQISETEQQFYIPVAAQTREMVSS
AFFXXXXXXXXX-------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXX
XXXX-XX----XXXXXXXX----XXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXNPE
ESCDLLGDIQTCMTKSMGEKAR-RKRS---NATXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXX-----XX-X--XXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDGKGRWGC
---------GGLRDGAKLALNQG-----------------------------------PG
PDL-IRMVTKQPENPL-LELLKPLLNIIRCSMRSS----STPQE---KDLLQKTARIFSQ
DLFHARQYCRDLDNAEEMLHPRLAWLVQQAGRQVDASISLYYFNGSLYLLRVLKGNAVHK
AQGETTSDC----------------------------------------------DKPGD
----------------PKAPSGLNLSFVVPLYSSALSSFLTRRNSPLTAPMFLSLFTRHP
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------XXXXXXXXXXX
X--XXXXXXXXXXXXXXXXX----XXXXXXXXXXXXXXXXXXXX----------------
--------------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXX--X------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXX----------------------------------------------
-----XXXXXXTL-----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------RFTISSSKK

------------------------------LPP--------------PK-H---------
-----ATSTEVTEPSSVPEADPRGVLRKGRAFLDLFWDIAKPEQDVRLEATENLLRHLRD
GGEDE-ELKYALKRLVEGLGATREAARPGFSLALAQVLQAFEEIPLCSVLEQIKEKHNLE
KVKKKLVRNAAFGNFFGVMALFQSGRLVKDQKALLESIQLLQQLAHHQTHLRDLPSKTLV
DILSEVPETVFEEVLFGILQ-ADLTSAFKSPENLHLLLVGMQKFPGVLKPKKLKKLFGSP
TIVNEENIPRLVELLESAAKSEKKDKKLPSVGLDLLQVSLKEGAFELFWN-EAVENGLFK
EKSGPVSYMCYRLLGSALPLLSLDQLQMVLKGRVMQHYGEHVVTTQLPDRFKFAPEMEAY
VDKFLTSC-DDPERQLAMMIGFSTLTNQGYPVVPSVWRVVRHLQ--PVAL----------
--QKYVDWLKDMFLKPDLDCCLDFSTNRQKQNQENK------NIAQHKIARLRKWIIHRL
MSI-VESP-VKKEESLVMDISRFCFFHAFFETKKKTSQIPETNVLISEPLDEQAHSLAAN
YFFGLLQTLNTLTVLGDTTEAAALREKHIHGVTADGKLWIFHLVEYASELLSSEK-YVKA
VKPF-TKEQRDAWERTLQSVKNLQKKKSKSDSAKHFAFQQLLLLMAIHLFKN------PS
ETMDLLSDLLNCTERAFSKEAKKKKTG--KT--ENAEPEWVEVIVEILLSLLAQPSLLIR
RISNSVFGRICPNLTKKGLQLILDVLDPYQDQDEESAVVVVEES-EKKIKSEQ------D
MDDD--DDESEDS--SDDGDSEE--ENDS-EDEKNEE-VDEDFRSQLINVLQAGNAL---
GEDES---DEELDDEAMMALDKNISALFAEQQKRIQAKKDEKDRIRKEKILRRDDFKIKV
LDLVEVFLSKQPENPLVFDIIEPLLQVIEQCMSSD----SDKQE---VDFLQKTAHIFTN
SLCRAKQYCKRVDVLQDDLHTFVERLVKKACKHTDSSVALYYFSASLYLLKVLKGNVSVK
EADKHHPTGL--------------------------------------------------
----------SGKSRLLSSTGCLDVERVTLIYQQALTQFLSKRNSALTSSMFLDLFTRF-
------------------------------PIMCKPLIDILV-------KSITAGARQHQ
QAQACLLLQKVLPLRELKLS----TTKEEWEELIRESISQVTES----------------
--------------------------LKVPDKLRVKAEKEKVARSLELLNFLL---KTVT
QQKLHVELMELDKVLVALSQ---------QEGI----GKSARLDSL-----YWNVMRWLN
YTK-----------------------PKKEK-TA----NKPVQEAEPPKRKKKGFLPETK
KRKNRK------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

---------------------------------------------------------IDS
QDVAELKSPGEVTQSGALPADRHGLLQHSREFLDFFWDIAKPQQETRLEATEKLLEYLRT
RPQGS-EMKYALKRLITGLGVGRETARPCYSLALAQLLQSFEDIPLCSILQQIQEKYDLR
QVKKATMRPALFGNLFGVLALFQSGRLVKDQEALMKSVKLLQVLALHYNHLQEQPQKALV
DILSEVPEAMLQEILPKVLK-GDLNMTLSSPERLELFLLAQQKVP-----AKLENMMGSV
NLFSDENVPRLVNVLRMAATAAKKERKLPPVALGLLRLALKEDKFPQFWK-EVVEQGLLK
KQSWPASYLCFRLLGVALPLLSKEQLQMVMRGDLIRHYGEHMVTAKPPNQFRFGPEMDKY
VGTFLEGCQDDPERQLAVLVAFSSVTNQGLPVVPTVWRVVQFLS--PPAV----------
--QGYVAWLQDMFLQPNLDSLVDFSTTNQKKAQDASL-----HVPERAVSRLRKWLIHRL
VSI-VDNTHLEKEDALVEQVARFCLFHSFFVTKKPTSQVPETKQQFSFPLESQSREVVSN
AFFSLLQTLSTH-------------FKQAPGQTQRGQSWAYRLVQWADKLLNHSR-SVTT
VLPF-TTQQHQAWDRMLQTLRDLEAHSTEA-R--AAAFQHLLLLVGIHLFKS------PA
ESCDLLDDIQTCIKKSLGEKTR-RSRT---KAINSQEPPWVEVLVEILLALLAQPSHLMR
QVARSVFGHICSHLTPHALQLILDVLNPETSQDED-ENVVVTDDSDEKQLENA-----ED
KSDD-----SEDNKNAESEDESE-EEEESEEEDRDGD-VDQGFREQLMAVLQAGKALGGA
DSEDE----EELGDEAMMALDQSLASLFAEQKLRIQARRDEKNKLQKEKMLRR-DFQIRV
LDLIEVLVTKQPENPLVLQLLQPLLRIIRRSMRTS----SCQQE---QELLHKTARIFTH
HLCRARRYCHDLGDLVETLHTQVEQLVQQASRQADSSVALYHFNASLYLLRVLKGSSGEG
CAPETQKKPRAGTDTS---------------------------------------PKPKG
PQ----------------TASCLDWNLVTPVYSSALSSFLTKRNSPLTVPMFLSLFSRH-
------------------------------PVLCKSLLPILV-------QHVAGPARPRH
Q--ACLLLQKTLSMRELRAC----FEDPEWKQLIGQILAKVSEN----------------
--------------------------LRALGHAQTKAEHQKELSSLELLNTLF---RSVL
HEKLTLDLTGLLGVLQGQQQ---SLQQSLRQGEHS--TGSSRLYDL-----YWQAMKVLG
VQ-R----------------------PKLEKKDTKE-VPSAVQSPMSMKRKKKGFLPETK
KRKKRKSEDVAQEE-----------GAKPTATAEGQPPSTGKKKK-RKRA--KD------
------------------------------------------------------------
----------------------KAPAQSQVNGTPA-VKRPAPDTS---------------
----------------------------------------------------TLDPSTP-
AKTPKLQKKHQKPSQVNGATPVS---PVEPAVKKKHQKALLKKEVSGKLPQ---SALPRK
KAR--LSLASRSPSLFQSMARKKKVQTLRFTI--SSSKK

------------------------------------------------------MAEMKS
PAKAEPASPAEAA-----QDERRGLLEHSREFLDFFWDIAKPEQETRLQATEKLLEYLRT
RPS-GSEMKYALKRLVTGLGVGREAARPCYSLALAQLLQSFEDIPLCSILSQMQEKYNLQ
TVNKAMMRPALFANLFGVLALFQSGRLVKDQDALMKSVRLLKILSHHYNHLQGQPIKVLV
DILSEVPESMFQEILPKVLK-GDLKVILSSPKYLELFLLAQQRVP-----AKLESLMGSV
DLFSEENIPSLVNVLRMAANSVRKEHKLPDVALDLLRLALKENKFTLFWK-EILEQGLLK
KPCWSTSYMCFRLLGASLPLLSEEQLHLVMRGDLIRHFGEHMVISKPQNLFKFIPEISTY
VSTFLEGCQDDPERQFAMMVAFTSITNQGLPVMPTFWRVTRLLS--SKAL----------
--QSYVAWLRDMFLQPDLDSLVDFSTANQKRAQDASL-----NVPERSVVRLRKWIIHRL
VSL-VEHLHLEKDDAVVDQVARFCLFHAFFKTKKSTPQIPETKQQFSFPLDDRNRSVIVS
AFFSLLQTLSVK-------------FRQTPDLNESGKPWTYRLVQLADMLLNHSR-NVTI
VTPF-TTQQRQAWDQMMSTLKELEARSSET-R--AVAFQHLLLLVGLHLFKS------PT
ESCDVLGDIQTCIKKSMEQNPR-RSRS---KAKASQEPVWVEVMVEILLSLLAQPSNLMR
QVVRNVFGHICSHLTPRGLQLILAVLNPETNEDED-DNVVVTDDTDEKQLKDG-----ED
EDLD-----SEDNKNSESDVDS-EDGEESEEEDRDKD-VDPGFRQQLMEVLQAGNALGGV
DSEE---EEEELGDEAMMALDQNLASLFAEQKLRIQARKEEKNKLQKEKKLRR-DFQIRV
LDLIEVLVTKQPEHPLILELLEPLLSMIQHSMRSKG---STKQE---QDLLHKTARIFMH
HLCRARHYCHEVGPCAEALHAQVERLVQQAGSQADASVALYYFNASLYLLRVLKGNAARR
PQ-DGRKLRGADTQSE---------------------------------------PKDPE
A---------------Q-AANCLDLDFVTRVYSTALESLLTKRNSPLTVPMFLSLFSRY-
------------------------------PVICKNLLPILV-------QHVAGPSRPRH
QAQACLLLQKTLSARELRVC----FEDPEWEQLIGQVLAKVAQT----------------
--------------------------LQTLGEAQSKGEHQRELSTLELLNTLF---RTVN
HEKLSVDLTSLLGLLQSKQQ---KLQQSLQQGNHS--SGSNRLYDL-----YWQAMKMLG
VQ-----------------------RPKSEKKNAKA-VPSESQSPISMKRKKKGFLPETK
KRKKLKSEDTTPGKDAASGQDVVTADATPAATGKDQPPST--GKRKRRR--VKANTPSQV
NGTPV-------------------------------------------------------
------------------------------------TKSPTPNNL---------------
----------------------------------------------------TLSPSTP-
AKTPKLQKKKEKLSQVNGTTPVS---PIEPEGKKHHQKAVPTKEVLRKS---PQSALPRK
RAR--LSLVSRSPSLLQSGLKKRKVARRKVQTP------

------------------------------------------------------AVEMEK
RDGAAAMSPGEAAKGGARPADRQGLLQHSREFLDFFWDIAKPEQETRLQATEKLLEYLRE
RPEGS-EMQYAQKRLIAGLGMGRETARPCYSLALAQLLQSFEDIPLCSILQQIQEKHDLR
TVKKVMKRPALFANLFGVLALFQSGRLVKDSEALMKSVKLLQALAQHYNHLQEQPQKALV
DILSEVPDVMWQELLPKVLK-PDLNSILVSPEHLEIFLLAQQKVP-----VQLEKLMGSV
NLLSDENIPRLVNVLKLAASSVKRERKLPTVALDLLRLALREDKFPWFWN-EIVEQGLLK
KQFWPASCVCFRLLGASLPLLSKEQLQLVMRGDTIRHYGEHVVTAKYPSQFKFASEMNEY
VGTFLEGCRDDPERQLAVLVAFTSITNQGLPVVPTYWRVVRFLS--SPAL----------
--KGYVAWLRDMFLQPDLDSLVDFSTGNQKKAQDASI-----HGPERAVFRLRKWIILRL
VSI-VDSLHLEKEEALIEEVARFCFFHSFFETKKPTSQIPETGQRFSFPMEGRARAVVSS
AFFSLLQTLSTQ-------------FKQALEQTQDKQPWTYRLVQFADMLLNHSR-NVSP
LTPF-TTQQRQAWTRMLQTLKELEACSSEA-KAKATAFQHLLLLVGIHLFKN------PT
ESCELLGDIQTCIQKSLGEKTR-RTRS---KAAKPQEPPWVEVLVEILLALLAQPSHLIR
QVARSVFSHVCAHLTPRALQLILDVLNPEQSEDED-NNVVVTDDSE-KQLENE-----ED
KSSE-----SEDNKNSESEDGSE--EEESDEEDRDGD-VDPGFREQLMAVLQAGKALGGV
DDD-D---DEELGDEAMMALDENLASLFAEQKLRIQARRDEKNKLQKEKALRR-DFQIRV
LDLIEVLVTKQPENPLVLELLEPLLNIIRRSMRTS----STKQE---QDLLHKTARIFTH
HLCRSRRYCRDVGNCVETLSTQVERLVQQAAHQADSSVALYYFNASLYLLRVLKGNTADR
SIHKPQKKEKAGT--S---------------------------------------TKPKG
PE----------------AASCLDLNLVTPIYSSALSSFLTKRNSPLTIPMFLSLFSRH-
------------------------------PMLCKSLLPVVV-------QHVTGQTRPRH
QAQACLLLQKTLSMRELRLC----FEDPEWEQLTGQILAKVTEN----------------
--------------------------LRALGEAQTKSEQLKNRSSLELLNTLL---WIIN
HENLTVDLTVVLGVLQSQQQ---YLQHRVRQKEQV--AGSSRLYDL-----FWQAMRFLG
VQ-R----------------------PKSEKKEAKE-V-SATQSPVSMKQKKKGFLPETK
KRKKRKSEGTPPEE-----------AAKPAATGGDQPQPPSTGKK-RKRK--KA------
------------------------------------------------------------
----------------------KVAAQAQAEGTPA-AKSPATE-----------------
----------------------------------------------------SLSPEPP-
AKTPKLRKRKRKLSQVNGATPVS---PTEPVVEKQYQKELPQKGVSGKSPQSPQSALPRK
KARLRLSLANRSPSLLQSGAKKKKAQLRKAAKP------

-----------------------------MRPDLTWKRLSS------EPTCSTSMAEPAS
VEVIEPLAPGEAQKSGARPADRHGLLKHSREFLDFFWDIAKPQQETRLEATEKLLEYLRA
KPKGSSEMKYALKRLITGLGGGREAARPCYSLALAQLLQSFEDIPLGSILQQIQEKHDLQ
KVKKGMMRPALFGNLFGVLALFQSGRLVKDSEALMKSVKLLQALGQHYNHLQEQPQKALV
DILSQVPETTLQEILPKVLK-PDMNSVLGSPEHLELFLLAQQKVP-----KKLEKLMGPV
NLFSDENIPRLVTVLKTVANSVKKERKLPTMALDLLRLALQEDKFPWFWK-EVVEQGLLK
KQFWPASYLCFRLLGAALPLLSKEQLQLVMQGDLIRHYGEHMVTAKLPKQFKFAPEMNEY
VGAFLEGCKDDPERQLALVVAFTSITNQGLPVVPTFWRVVQFLS--PTAL----------
--KGYVAWLRDMFLQPDLDSLVDFSTYNQKKTQDASF-----HGPERAVFRLRKWIILRL
VSI-VDNLHVEKEEALIEEVARFCFFHSFFETKKPTSQIPESEQHFTLALDGRTREVVCS
AFFSLLQTLSTQ-------------FRLAPEQTADGRPWTYHLVQFADMLLNHSR-NVAP
LTAF-TTQQRQAWDRMLKTLKELDTLSSEA---KATAFQHLLLLVGIHLFKS------PA
ESCDLLGDIQTCIKKSLGEKTR-RTRS---KATNPQEPPWVEVLVEILLSLLAQPSHLMR
QVARSVFGHVCSHLTLRALQLILDVLNPEESQDED-DNVVVTDDSEEQPLGGA-----ED
KSSDGEDSKGSKG--SES--EEESD-DDSDEEDRDGD-VDQGFREQLMAVLQAGKALGGA
DSEDD--DDEELGDEAMMALDKSLASLFAEQKLRIQARKDEKNKLQKEKALRR-DFQIRV
LDLIEVLVTKQPENPLVLELLEPLLLVIRRSMRSNS---SAKQE---QDLLHKTARIFTH
HLCRSRHYCRTAGDRVETLYARLEQLVQQASQQADSSVALYHFNASLYLLRVLRGSTVDK
PAHKAQKKEKASKD---------------------------------------AS-----
-----------SQSQGPEAASCLDLSLVTPIYSSALSSFLTKRNSPLTVPMFLSLFARH-
------------------------------PMLCKNLLPIVV-------EHVTSHTRPRH
QVQACLLLQKTLPTRELRVC----FKDPEWKQLLGQTLGKVTEI----------------
--------------------------LRTLGEAETKSGHQKDLAALELLNTLF---RNFY
HEKLTVSLTAILGVLQSQQP---RLQQRLQQGGHS--AGSSRLHDL-----YWQAMKFLG
VQR-----------------------PKPEKDTKEA-PQATQQSPVSMKRKKKGFLPETK
KRKKRKPEATTQEV----------AAAKPEAASGDQPPSA--GKKKK-KKKMKTT-----
------------------------------------------------------------
----------------------KSPAQSQVNGTSA-AKSPTPEPP---------------
----------------------------------------------------AVSPSTP-
TKTPKPQKKSQKLSQMNEATPLPRQSPEEPAAKKRQ-KKLPQKGVSGKSPQ---SALPRK
KAR--LSLASRSPSLLQSGAKKV-QL-RKAKK--L----

-MG-----QGKQSPGYCWHLRPLPGPPPADLPQLGWTQNKDQVSWWPGAIPASCMAEIDG
QDVAEPTSPGEATQSGALPADRHGLLQHSREFLDFFWDIAKPQQETRLEATEKLLEYLRT
RPQGS-EMKYALKRLITGLGVGRETARPCYSLALAQLLQSFEDISLCSILQQIQEKYDLH
QMKKAMMRPALFGNLFGVLALFQSGRLVKDREALMKSVKLLQALSLHHNHLQEQPQKALV
DILSEVPEAMLQEILPKVLR-GDLNMVLGSPELLELFLLAQKKVP-----EKLESMMGSV
NLFSDENVPRLVNVLRTAATAVKKERKLPRMALDLLHLALKEDKFPRFWK-EVVEQGLLK
KQSWPASYLCFRLLGTALPLLSKEQLQMVLRGDLIRHYGEHMVTAKPPSQFRFGPEMDEY
VGTFLEGCKDDPEQQLAVLVAFSSVTNQGLPVVPTVWRVVQFLS--PPAL----------
--QGYVAWLQNMFLQPNLDSLVDFSTANQKKAQDASL-----HVPERAVFRLRKWLIHRL
VSI-VDNMHLEKEDALVEQVARFCLFHAFFVTKKPMSQIPETKQKFSFPLEGQSREVVGN
AFFSLLQTLSTH-------------FKQAPDQTRGGQSWAYRLVQWADKLLNHSR-GVTT
VLPF-TTQQHQAWDRMLQTLRDLEAHSTEA-R--AAAFQHLLLLVGIHLFKS------PA
ECCDLLNDIQTCIKKSLGEKSR-RSRT---KATNSQEPAWVEVLVEILLSLLAQPSHLMR
QVARSVFGHICPHLTPRALQLILDVLNPETSQDED-ENVVVTDDSDKQQLENT-----ED
ESDD-----SEDNKNAESEDESE-EEEESEEEDRDGD-VDQGFREQLMAVLQAGKALGGA
DSEDE----EELGDEAMMALDQSLASLFAEQKLRIQARRDEKNKLQKEKTLRR-DFQIRV
LDLIEVLAIKQPENRLVLELLQPLLRIIRRSMRTS----SSQQE---QELLHKTARIFTH
HLCRARRYCHDLGGLVETLHAQVEQLVQQASRQADSSVALYHFNASLYLLRVLKGNSGEG
CAPETQKKPRAGTNTI---------------------------------------PKPKG
PQ----------------TASCLDLNFVTPVYSSALSSFLSKRNSPLTAPMFLSLFSRH-
------------------------------PVLCKSLLPVLV-------QHIAGPTRPRH
QAQACLLLQKTLTMRELRAC----FEDPEWKQLVGQVLAKVTEN----------------
--------------------------LRALGQAQTKSEHQKELSSLELLNTLF---RSIN
HEKLTLDLTGLLGVLQGQQQ---SLQQSLRQGAHS--TGSNRLYDL-----YWQAMKVLG
VQ-R----------------------PKLEKKDTKE-VPSAVQSPVSMKRKKKGFLPETK
KRKKRKSEDVTQEE-----------VAKPVATAEEQSPSTGKKK--RKRT--KA------
------------------------------------------------------------
----------------------KAPAQSQVNGTPA-VKRPAPDTS---------------
----------------------------------------------------TLSPSTP-
AKTPKLQKKQQKPSQVNGAAPVS---PTEPAVKKKHQKALPKKEVSGKSPQ---SALPRK
KAR--LSLASRSPSLLQRGARKKKVQVKKVKR--S----

MRGAGLRNRGTEGSGS-HGGRALPAG--AALPRK---RRSGRA---APRAAAGGMAVMEE
ME---ETEQMEQRGGGAAVSDPRGVLRQGRAFLDFFWDIAKPEQEVRLAATESLLRHLRE
GKKDD-ELKYTLKRLGEGLGATREAARPGFSLALAQVLQAFEEIPLCSILEQIKEKHNLE
KVKKKLVRNAAFGNFFGVMALFQSGRLVKDRKALLESIQLLQQLTNYQTHLRDLPRKTLI
DITSEVPETVFEEVLFDILQ-GDLSSAFTSPENLHLLLVGMQKFPGVLKPKKLKKLFGSP
TVVNKENTSRLVELLKSAAKSEKEDKKLPSVVFDLLQVALKEGAFELFWN-EVVEDGLLK
EKSGPVSYMCYRLLGSALPLLSMEQLQVVLKGKVMLHYGEHVVATQSPQGFKFAAEMEGY
IDTFLSGC-DDPERQLAVMMGFSTLTNLGKPVLLSASKVVRHLQ--AVAL----------
--KKYICWLKDMFLRPDLDCCLDFSSNRQKQNRENA------DIAQQKTARLRRWIMHRL
VNI-TESA-TRKEESFVMDIARFCFFHAFFVAKKKNSKIAEASVLPSEPLNERDHTETEN
YFFGLLQTLNTMPVLGDTAEAAALREKHVHGVTADGKLWIFLLVEYANKLLSSE--HVKA
VKPF-TKEQRDIWERTLQSVKNLQKKGNKSDSAKVGAFQQLLLSMAIHLFKN------QS
ETEDVLSDLLNCTERAFSKEAKK-K----KT--DNSEPGWVEVMVEILLSLLAQPSLLLR
RISKNVFVSICPNLTKRGLQLILDVFDPNQEENEESAVVVMEEP-NKKTKSAQ------D
TD----EEESEDS--SDEDS-------TDSEDEETEE-VDDNFRSQLMKVLQAGNT---E
EGDKS---DEELDDDAMMALDKNISALFAEQQKRIQAKKDEKDRMRKEKILRR-DFKAKV
LDLIDVFLLKQAENPLVFDIIEPLLQLIEQCMSSD----SDKQE---VDILQKTASIFKN
SLCRNKQYCKRVASLQEDVHALVQRLVKKACKHTDSAVALYYFSASLYLLKVLKGNTSST
LPPPEP-EK----QSDS-------------------------------------------
---------KAKQACQLLNPGCLDVEKVAVIYQQALTQFLSKRNSPLTFSMFHDLFRRF-
------------------------------PIMCKPLVDTLV-------EFITAAARQHQ
QAMACLLLHRVLLLHELKFF----VTEEEWEELITRSISQVIKLLLSWRLGGCLRNSEYL
LQLSLIPSLPRLVSMGHSRSAVILECLKTLGKPIMKAEKEKVAKSLELLNFLL---KTVT
EQKLNVKLAQVEKVLLSLKQ---------QEDF----GNSPRLDSL-----YWNVMRWLN
HTK-----------------------PKKEK-AA----SKPTQGAELLKRKRKGFLPESK
KRKNRKKGAQENGVGAGE------------DGDPAAPEEQPLGTQSPKHKKGFVPGGSKK
-HPK---------------------REGKENGV-----------A---------------
----------------------------KAGGGNLPTASEGDAVA---------------
------------------------------------------------------------
-----------------------------DKKKKRKRKNRKRKGASGNEAE---QAPAAK
KTK--GSVVQETQ-QKQDKAKKKKK-EKQA--PVLQE--

------------------------------------------------------MAEMES
EDVAEPVSPEEATKSGPRPADRQGLLQHSREFLDFFWDIAKPQQEARLEATEKLLEYLRT
RPEGS-EMKYALKRLITGLGVGRETSRPCYSLALAQLLQSFEAIPLCSVLQQIQETHDLQ
KVKKTMIRSALFANLFGVLALFQSGRLVKDQEMLMKSVELLQVLAQHHNHLQEQPQKALV
DLLSETPEASLKEILPKVLP-ANLNMVLGSPEHLELFLLAKQKVP-----ETLEKLLGPV
NLFSDENLPRLVDVLKVASIAVKKERRLPAVALNLLRLALQEEQFPRFWE-DVVEQGLLK
KEYWPSSYLCFRLLGAALPLLSKVQLQLVMRGDLIRLIGEHLISAKHPDRFKFAPEMDEY
VGTFLKGCQDDPERQLALVVAFSSLTNQGHPVVPTFWRVVRFLS--PRAL----------
--GDYVAWLQAMFLQPDLDSLVDFSTSNQKRSQHFSL-----HGPERAVFRLRKWIILRL
VSI-VEDAQVEKEEALIEETARFCLFHSFFDTKKPMSQIPETGQPFSFPLQSRTREIVST
AFFSLLQALGSP-------------TKQGPGQTQDGRPWTYHLVQFADTLLSHSR-NVAT
VTAF-KAQQRQAWNRMLQTVKELETRSSEA-K----AFQHLLLLVGIHLFKS------PA
ESCDLLGDIQVCIQKSLEGKTR-RTRS---KAADLQEPPWAEVLVEVLLALLAQPNHLMR
QVARSVFSHICPHLTPRALQLILDVLNPEKSQEED-DNVVVVDDSEEEEKEEL-----ED
AEDKK----SQDG--SDREDSEESEEEESEEEDRDMD-VDEGFREQLMAVLQAGKAPGEV
DNEEE--EEEELGDEAMMALDQELSSIFAKQKLRIQARRDEKNKLQKEKVLRR-DFQIRV
LDLIEVLVTKQPEHPLVLELIEPLLLIIRRSMRAS----STKQE---QDLLRKTARIFMH
NLCHSRHYCRNLGDSVGTLHTQVERLVQQAGHQADSSIALYYFNAAFYLLRVLKGNTADS
ETLKAPKQQKASNGSS---------------------------------------PESQA
PE----------------AASCLDLSLVTPAYSAALSSFLTKRNCPLTIPMFLSVFTRH-
------------------------------PVLCKNLLPIMA-------QHMTGPTRARQ
QPGALAAPQAALSPPAQRGGTGWVVAERQPRQVAPAAAGGCSQN----------------
--------------------------LQTLGKAQAKSEQQKELSSVELLITLL---RAVK
QQDLTVDLTTILGVLQGVQP---SLRQSLQQGEHV--AGSSRLYDL-----YWQALKFLG
VQR-----------------------PKSEKKSVRE-VPSAPQNPISMKRKKRGFLPETK
RRRKHKPEKTPEDE------------ARQPSTGGEQPPSS--GRRRRRRT--LS------
------------------------------------------------------------
----------------------DKRPSTPAVPT---MSPSTPAIP---------------
----------------------------------------------------TTSPSTP-
AKSPKLRKKRQKQSQVNGATPVA---SSEPASKKLRQKALHKKGRSGKSPW---STPPQK
RSR--LSFSNGIPSFLRSGAKKKKVQPKTGQEP------

---------------------------------------------------------MES
QDVGEPMSLGEGTKSSVRPADRHGLLKHSREFLDFFWDIAKPEQETRLEATEKLLEYLRT
RPVGS-EMKYALKRLITGLGVGRETARPCYSLALAQLLQSFEDIPLCSILQQIQEKHDLQ
KVKKAMMRPALFANLFGVLALFQSGRLVKDSEALMKSVKLLQALAQHYNHLQEQPQKALV
DILSEVPEATLQEVLPKVLK-ADLNSVLGSPEHLELFLLAQQKVP-----TKLEKLMGSV
NLFSDENIPRLVTVLKMAATSVKKERKLPAVALDLLRLALQEDKFPRFWK-EVVEQGLLK
KQFWPASYLCFRLLGAALPLLSKEQLQLVMRGDVIRHYGEHMVTAKFPNQFKFAPEMNEY
VGTFLEGCRDDPERQLAVVVAFTSVTNQGLPVVPTFWRVVRSLS--ASAL----------
--KGYVAWLRDMFLQPDLDSLVDFSTSNQKKAQDASL-----HGXERAVYRLRKWIILRM
VSI-VDSLHLEKEEALIEEVARFCFFHSFFEKKKPTSQIPETEQQFSFPMEGRAREVVSN
AFFSLLQTLSTQ-------------FRQAPEQTQDRQPWTYRLVQFADMLLNHSR-NVAP
LAPF-TTQQRQAWDRMLQTLKELEARSSEA-K--ATAFQHLLLLVGIHLFKS------PT
ESCDLLGDIQTCIKKGLGEKTR-RTRS---KATNPQEPPWVEVLVEILLALLAQPSHLIR
QVARSVFSHICSHLTPRALQLILDVLNPEQSQDED-DNVVVTDDSE-KQLEDE-----ED
KTSD-----SEDNKNSESEEESN--EEESDEEDRDGD-VDPGFREQLMAVLQAGKALGGV
DNEDD---EEEVGDEAMMALDQNLASLFAEQKLRIHARRDEKNKIQKEKALRR-DFQIRV
LDLIEVLVTKQPENPLVLELLEPLLNIIRRSMRTS----STKQE---QDLLHKTARIFTH
HLCRSRHYCHDVGNCVETLYTQVERLVQQASHQADSSISLYYFNASLYLLRVLKGNTADS
SICKTQKKEKAGTDTS---------------------------------------TKPKG
PK----------------ATSCLDLSLVTPVYSSALSSFLTKRNSPLTIPMFLSLFSRH-
------------------------------PVLCKSLLPVVV-------QHVTGQVRPRH
Q--ACLLLQKTLPIRELRLC----FEDPEWEQLVGQILAKVTEN----------------
--------------------------LRALGEAQTKSEHLKERSSLELLNALF---RIIN
HEKLTVDLTCIRSVLQSQQP---NLQQRVQQGEHS--TGSSRLYDL-----YWQAMKILG
VQ-R----------------------PKSEKKDAKE-VPSATQNPISMKRKKKGFLPETK
KRKKRKSEGTTQEE-----------NAKPTSISGDQP--PSTGKKRKKRM--KA------
------------------------------------------------------------
----------------------KVAAQAQVNGTPA-IKSPDPEPP---------------
----------------------------------------------------AANPSTP-
AKTPKLQKKNRKLSQVNGDTFVS---PTEPAGEKQHQKELPKKGVSGKSPH---SALPQK
KAR--LSLASKSPSLLQTGAKKKKAQTLRFTISSSK--K

------------------------------------------------------MAEMKS
PTKAEPATPAEAS-----QSDRHSLLEHSREFLDFFWDIAKPDQETRLRATEKLLEYLRT
RPN-DSEMKYALKRLITGLGVGREAARPCYSLALAQLLQSFEDIPLCDILDQIQEKYSLQ
AMNKAMMRPSLFANLFGVLALFQSGRLVKDKEALMKSVQLLKILSQHHNHLQGQPIKALV
DILSEVPESMFQEILPKVLK-GNMKVILRSPKYLELFLLAKQRVP-----TKLESLMGSV
DLFSEDNIPSLVNILKVAANSVKKEHKLPNVALDLLRLALKENRFELFWK-KVLEEGLLK
NPSWTSSYMCFRLLGASLPLLSEEQLQLVMRGDLIRHFGENMVISKPQNLFKIIPEISTY
VGTFLEGCQDDPKRQLTMMVAFTTITNQGLPVMPTFWRVTRFLN--AEAL----------
--QSYVAWLRDMFLQPDLNSLVDFSTTNQKRTQDASL-----NVPERAVFRLRKWIIHRL
VSL-VDHLHLEKDEAVVEQIARFCLFHAFFKTKKATPQIPETKQHFSFPLDDRNRGVFVS
AFFSLLQTLSVK-------------FRQTPDLAENGKPWTYRLVQLADMLLNHNR-NVTS
VTSL-TTQQRQAWDQMMSTLKELEARSSET-R--AIAFQHLLLLVGLHIFKS------PA
ESCDVLGDIQTCIKKSMEQNPR-RSRS---RAKASQEPVWVEVMVEILLSLLAQPSNLMR
QVVRSVFGHICPHLTPRCLQLILAVLSPVTNEDED-DNVVVTDDADEKQLQHG-----ED
EDSD-----NEDNKNSESDMDS-EDGEESEEEDRDKD-VDPGFRQQLMEVLKAGNALAGV
DNEEE--EEEELGDEAMMALDQNLASLFKEQKMRIQARNEEKNKLQKEKKLRR-DFQIRA
LDLIEVLVTKQPEHPLILELLEPLLNVIQHSMRSKG---STKQE---QDLLHKTARIFMH
HLCRARRYCHEVGPCAEALHAQVERLVQQAGSQADASVALYYFNASLYLLRVLKGNTNKR
HQ-DGQKLHGADTGPE---------------------------------------PKDSE
D---------------Q-AANCLDLDFVTRVYSASLESLLTKRNSSLTVPMFLSLFSRY-
------------------------------PVICKNLLPVLA-------QHVAGPSRPRH
QAQACLMLQKTLSARELRVC----FEDPEWEQLITQLLGKATQT----------------
--------------------------LQTLGEAQSKGEHQKELSILELLNTLL---RTVN
HEKLSVDLTAPLGVLQSKQQ---KLQQSLQQGNHS--SGSNRLYDL-----YWQAMRMLG
VQ-----------------------RPKSEKKNAKD-IPSDTQSPVSTKRKKKGFLPETK
KRKKLKSEGSTPEKNAASQQDAVTEGAMPAATGKDQPPST--GKKKRKR--VKASTPSQV
NGITG-------------------------------------------------------
------------------------------------AKSPAPSNP---------------
----------------------------------------------------TLSPCTP-
AKTPKLQKKNEKLSQVNGATPVS---PIEPESKKHHQEALSTKEVIRKSPH-PQSALPKK
RAR--LSLVSRSPSLLKSGVKKRRVASRRVQTP------

---------------------------------------------------------MGS
RELAEPLSPGEATQSGARPADRHGLLKHSREFLDFFWDIAKPEQETRLAATEKLLEYLRG
RPKGS-EMKYALKRLITGLGVARETARPCYSLALAQLLQCFEDLPLCSILQQIQEKYDLC
EVKKTMLRPALFANLFGVLALFQSGRLVKDQEALMKSVKLLQALAQYQNHLQEQPRKALV
DVLSEVSVATLQEILPEVLK-ADLNTILSSPEQLELFLLAQQKVP-----SKLKKLVGSV
NLFSDENVPRLVNVLKMAAASVKKDRKLPAIALDLLRLALKEDKFPRFWK-EVVEQGLLK
MQFWPASYLCFRLLGAALPLLTKEQLQLVLRGDVIRHYGEHVCTAKLPKQFKFAPEMEDY
VGTFLEGCQDDPERQLAVLVAFSSVTNQGLPVAPTFWRVVRFLS--PPAL----------
--RGYVAWLRDMFLQPDLDSLVDFSTNNQKKAQDASL-----HVPERAVFRLRKWIIFRL
VSI-VDSLHLEMEEALTAQVARFCLFHAFFVTKKPTSQIPETKQLFSFPLESQAREAASS
AFFSLLQTLSTQ-------------LKQATEQTRGGQPWTYHLVQFADLLLNHSH-NVTT
VTPF-SAQQRQAWDRMLQTLKELEAHSSEA-R--AAAFQHLLLLVGIHLLKS------PA
ESCDLLGDIQTCIRKSLGEKPR-RSRT---KAIDPQEPPWVEVLVEILLALLAQPSHLMR
QVARSVFGHICSQLTPRALQLILDVLNPETSEDE--DHVVVTDDSDERRLKGA-----ED
KSED-----GEDNRSSESEEESE--GEESEEEERDGD-VDQGFREQLMTVLQAGKALGGE
DSEDE----EELGDEAMMALDQSLASLFAEQKLRVQARRDEKNKVQKEKALRR-DFQIRV
SLGA----DRPPLPALTLAVLGATEALSARALAWG----RVWVWFPFSEMAALVLTTHRH
HLCRARRYCHDLGERTEALHAQVERLVQQAGRQPDSATALYHFNASLYLLRVLKGSTAEG
CGHETQEKQKAGTDPS---------------------------------------PVP--
-----------T---GPQAASCLDLNLVTRVYSSALSSFLTKRNSPLTVPMFLSLFSRH-
------------------------------PVLCKRLLPILV-------QHVTGPVRPRH
Q--ACLLLQKALSLREVRSC----FEDPEWKQLMGQVLAKVTEN----------------
--------------------------LRVLGEAQTKTEHQQALSSLELLNALF---RTCK
QEKLTLDLTVLLGVLQGQQQ-------SLQQRAHS--TGSSRLHDL-----YWQAMKTLG
VQR-----------------------PKLEKKSAKE-APSATQSPTSKKRKKKGFLPETK
KRKKRKSEDGTLAE-----------DGTPAATGGSQP--PSMGRKKRNRT--KA------
------------------------------------------------------------
----------------------KVPAQ--ANGTPA-TKSPVPGTP---------------
----------------------------------------------------TLSPSTA-
AKSPKLQKKSQKPSQVNGA-PRS---PVEPAGQKQHQKALPEKGVLGKSPL---SAPARR
KAR--LALVSRSPGLLQSGAKKKK--TLRF--TISSPKK

------------------------------------------------------------
----EPMAPGEATPSGLGPADRHDLLKLSREFLDFFWDIAKPQQETRLEATEKLLEYLRT
RPEGS-EMKYALKRLITGLGVGRETARPCYSLALAQLLQSFEDIPLCSVLQQIEEKYDLH
QMKKATVRPALFANLFGVLALFQSGRLVKDQEALMKSVKLLQALAQHYNHLQEQPQKALV
DILSEVPKATLREILPKVLK-ADLNTVLSSPENLELFLLAQQKVP-----MKLKKLMGSV
NLFSDENVPRLVDVLKMAATAAKKERKLPDIALALLRLALKEDKFPRFWK-EVVEQGLLK
KQFWPGSYLCFHLLGAALPLLSKEQLQLMMRGDLIQHYGEHIVTAKLPNKSKFAPEMEEY
VGTFLEGCRDDPERQLAVLVAFSSITNQGLPVVPTFWRVVRFLS--PPAL----------
--QDYVAWLQDMFLQPNLDSLVDFSTNNQKKAQDASC-----HVPERSVFRLRKWIILRL
VSI-VDCLHLEMDEALTEQVARFCLFHSFFVTKKPTSQIPETKQQLSFPLESQTREVVSS
AFFSLLQTFGTQ-------------FKRTPDQTQSGQPWTYRLVQLADTLLNNSH-YVAT
VIPL-TEQQRQAWDQMLQTLKELEAHSSEA-R--VTAFQHLLLLVGIHLFKS------PA
ESCDLLGDIQTCIKKSLGEKTR-RSRS---KAINSQEPPWVEVLVEILLALLAQPSHLMR
LVARSLFGHILPHLTPRALQLILDVLNPETSQDED-DHVVVTDDSDEKELKNS-----ED
KSED-----SEDNENAESEESSE--EAESDEEERDGD-VDQGFREQLMAVLQAGKALGEV
DSEDE----EELGDEAMMALDQSLASLFAEQKLRIRARRDEKKKLQKEKALRQ-SFQTRV
LDLIEVLVTKQPESALVLELLEPLLGIIRHSMRSSS---SSKQE---QDLLHKTARIFTH
QLCRARRYCHDLGDRVETLHSQVVQLVQQAGRQADSSVALYHFNASLYLLRVLKGNTAEE
CVHETQKQQKASAATS---------------------------------------TKPEG
PQ----------------TASCLDLNLVTPVYSTALSSFLTKRNSPLTVPMFLSLFSRH-
------------------------------PVLCKSLLPILV-------QHIAGSVQPRH
Q--ASLLLQKTLSMRELRSC----FEDSEWKQLIGQVLVKVTEN----------------
--------------------------LRTLGEAQSKAEHQKALSFLELGPVSCHHRIPIP
LQDLALDLTWLLEVLQSQQQ---NLQDSLQQGAHS--AGSSRLHDL-----YWQAMKILG
VQ-R----------------------PKLEKKDAKG-VPSATQSPVSMKRKKKGFLPETK
KRKKRKSEDGTQKE-----------DAKPAATGGAQPVSAGKKKKKRSRT--KT------
------------------------------------------------------------
----------------------KGPAQSQVNGTPA-AKRPAPDTP---------------
----------------------------------------------------SLSPGTP-
AKTPELQEKSQKPSQVNGATPVS---PSESA-GRKHQKALPRKGVSGKSPQ---STLPQK
KAR--LSLAIRRPSLHRGGAKKKKTQLKTLRFTISSSKK

---------------------------------------------------------MGS
RELAEPLSPGEATQSGARPADRHGLLKHSREFLDFFWDIAKPEQETRLAATEKLLEYLRG
RPKGS-EMKYALKRLITGLGVARETARPCYSLALAQLLHSFEDLPLCSILQQIQEKYDLC
EVKKTMLRPALFANLFGVLALFQSGRLVKDQEALMKSVKLLQALAQYQNHLQEQPGKALL
DVLSEVSVATLQEILPEVLK-ADLNAILSSPEQLELFLLAQQKVP-----SKLKKLVGSV
NLFSDENVPRLVNVLKMAAASVKKDRKLPAIALDLLRLALKEDKFPRFWK-EVVEQGLLK
MQFWPASYLCFRLLGAALPLLTKEQLQLVLRGDVIRHYGEHVCTAKLPKQFKFAPEMEDY
VGTFLEGCQDDPERQLAVLVAFSSVTNQGLPVAPTFWRVVRFLS--PPAL----------
--RGYVAWLQDMFLQPDLDSLVDFSTNNQKKAQDASL-----HVPERAVFRLRKWIIFRL
VSI-VDSLHLEMEEALTAQVARFCLFHAFFVTKKPTSQIPETKQPFSFPLESQAREAASS
AFFSLLQTLSTQ-------------LKQATDQTRGGQPWTYHLVQFADLLLNHSH-NVTT
VTPF-SAQQRQAWDRMLQTLKELEAHSSEA-R--AAAFQHLLLLVGIHLLKS------PA
ESCDLLGDIQTCIRKSLGEKPR-RSRT---KAIDPQEPPWVEVLVEILLALLAQPSHLMR
QVARSVFGHICSQLTPRALQLILDVLNPETSEDE--DHVVVTDDSDERRLKGA-----ED
KSED-----GEDNRSSESEEESE--GEESEEEERDGD-VDQGFREQLMTVLQAGKALGGE
DSEDE----EELGDEAMMALDQSLASLFAEQKLRVQARRDEKNKLQKEKALRR-DFQIRV
LDLVEVLVTKQPENALVLELLEPLLSIIRRSLRSS----SSKQE---QDFLHKTARIFTH
HLCRARRYCHDLGERAEALHAQVERLVQQAGRQPDSATALYHFNASLYLLRVLKGSTAEG
CVRETREKQKASTDPS---------------------------------------PVPTG
PQ--GPTLSLLK---GGQAASCLDLNLVTRVYSSALSSFLTKRNSPLTVPMFLSLFSRH-
------------------------------PVLCKRLLPILV-------QHVTGPVRPRH
Q--ACLLLQKALSLREVRSC----FEDPEWKQLMGQVLAKVTEN----------------
--------------------------LRVLGEAQTKAEHQQALSSLELLNALF---RTCK
QEKLTLDLTVLLGVLQGQQQ-------SLQQGAHS--TGSSRLHDL-----YWQAMKTLG
VQR-----------------------PKLEKKGAKE-VPSATQSPISKKRKKKGFLPETK
KRKKRKSEDGTLAE-----------DGTPAATGGSQP--PSMGRKKRNRT--KA------
------------------------------------------------------------
----------------------KVPAQ--ANGTPA-TKSPAPGTP---------------
----------------------------------------------------TLSPSTA-
AKSPKLQKKSQKPSQVNGA-PRP---PVEPAGQKQPQKALPEKGVVGKSPL---SAPARR
KAR--LSLVSRSPSLLQSGAKKKK--AQ-L--RKAGKP-

------------------------------------------------------------
------------------------------------------------------------
---DE-EMQYALKRLVEGLGATREAARPGFSLALAQVLQAFEEIPVFSVLEQIKEKHNLE
KVKKKLVRNAAFGNFFGVIALFQSGRLVKDQKALLESIQLLQQLAQYQAHLKDLPSKTIV
DILSEVPETIFEEVLFGILQ-ADFTSAFKSPENLHLLLVGIQKFPGVLKPKKLKKLFGSP
TIVNEENIPKLVELLQSAAKSEKKDKKLPSVGLALLEVSLKEGAFELFWK-EAVENGLFK
EKSGPVSYMCYRLLGSALPLLSLDQLQMVLKGKVMQLYGEHVVTSQLPDRFKFAPEMEAY
VDAFLNSC-DDPERQLAVMIGFSTLTNQGYPVVPSIWRVVRHLQ--PVAL----------
--QKYIDWLKDMFLRPDLSCCLDFSTSRQKQNPENV------NKTQHKIARLRKWIIHRL
MSI-IESP-VKKEEDLVMDISRFCFFHAFFETKKKTSQIPETNALLSEPLDEQAHSLAAN
YFFGLLQTLNTLSVLGDTAEAAALREKHVHGVTADGKLWIFLLVEYANELLSSEK-YVKA
VKPF-TKDQREAWERTLQSVKNLQKKENKADSAKIFAFQQFLLLMAIHLFKN------PS
ETMDLLSDLLNCTERAFSKEPKKKK-----T--ENTEPGWVEVIVEILLSLLAQPSLLIR
RISKSVFGRICPNLTKKGLQLILDVLDPYQDQDEESAVVVMEES-DKKSAQD--------
--TD--DEESEDS--SEEDDTEE--ENDSGDEEKDEE-VDEDFRSQLMNVLKAQNVLQK-
GEDES---DEDLDDEAMMALDKNISALFAEQQKRIQAKKDERDRIRKEKILRR-DFKIKV
LDLIEVFLSKQPENPLVFDIIEPLLQVIEQCMSSD----SDKQE---VDFLQKTALIFTN
SLCRAKQYCKKVEALQDDLHAFVERLVKKACKHTDSSVALYYFSASLYLLKVLKGSVSDK
SQQGLLVH-----SRSR-------------------------------------------
---------REPETNEVSSTGCLDVERVTAVYQEALTQFLTKRNSALTSSMFLDLFTRF-
------------------------------PIMCKPLVDTLV-------KSITAGARQHQ
QAQACLLLQKVLPLRELKLS----MTEEEWEELIRESISQVSET----------------
--------------------------LKMVDEFRVKAEKEKVARSLELLNFLL---KTVT
QQKLPVELMELDKVLVALNQ---------QEGI----GKSARLDSL-----YWNAMRWLN
HTK-----------------------PKKEKKAA----NKPVQAAEPLKRKKKGFLPETK
KRKNRKKGVQENGVAPGG------------NEAEQVPAAKKA------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--K--GSANQETP-QKQGKAKKKRK-EKKA---------

---------------------------------------------------------MGS
RELAKPLSPGETTQTGARPADRHGLLKHSREFLDFFWDIAKPEQETRLAATEKLLEYLRG
RPKGS-EMKYALKRLITGLGVSRETARPCYSLALAQLLQSFEDLPLCSILQQIQEKYDLH
QVKKTMLRPALFANLFGVLALFQSGRLVKDQEALMKSVKLLQALAQYQNHLQEQPQKALV
DILSEVSVATLQEILPEVLK-ADLNTILSSPEQLELFLLAQQKVP-----SKLKKLVGSV
NLFSDENVPRLVNVLKMAASFVKKDRKLPAMALDLLRLALKEDKFPRFWK-EVVEQGLLK
MQFWPASYLCFRLLGAALPLLTKEQLQLVLRGDVIRHYGEHVCTAKLPKQFKFAPEMEDY
VGTFLEGCQDDPERQLAVLVAFSSVTNQGLPVTPTFWRVVRFLS--PPAL----------
--QGYVAWLRDMFLQPDLDSLVDFSTNNQKKAQDASL-----HVPERAVFRLRKWIIFRL
VSI-VDSLHLEMEEALTAQVARFCLFHAFFVTKKPTSQIPETKQLFSFPLESQAREAASS
AFFSLLQTLSMQ-------------LKQATDQTRGGQPWTYHLVQFADLLLNHSH-NVTP
VTPF-SAQQRQAWDRMLQTLKELEAHSSEA-R--AAAFRHLLLLVGIHLLKS------PA
ESCDLLGDIQTCIRKSLGEKPR-RSRT---KAIDPQEPPWVEVLVEILLALLAQPSHLMR
QVARSVFGHICSQLTPRALQLIVDVLNPETSEDE--DHVVVMDDSDDRRLKGA-----ED
KSED-----GEENRSSESEEESE--GEESEEEERDGD-VDQGFREQLMTVLQAGKALGGE
DSEDE----EELGDEAMMALDQSLASLFAEQKLRVQARRDEKNKLQKEKALRR-DFQIRV
LDLVEVLVTKQPENALVLELLEPLLSIIRRSLRSS----SSKQE---QDLLHKTARIFTH
HLCRARRYCHDLGERAEALHAQVERLVQQAGRQPDSATALYHFNASLYLLRVLKGSTAEG
CVRETQEKQKASTDPS---------------------------------------PVPTG
PQ----------------AASCLDLNLVTQVYSSALSSFLTKRNSPLTVPMFLSLFSRH-
------------------------------PVLCKSLLPILV-------QHVTGPVRPRH
Q--ACLLLQKTLSMREVRSC----FEDPEWKQLMGQVLAKVTEN----------------
--------------------------LRVLGEAQTKAEHQQALSSLELLNALF---RTCK
QEKLTLDLTALLGVLQGQQQ-------SLQQGPHS--TGSSRLHDL-----YWQAMKTLG
VQR-----------------------PKLEKKGAKE-VPSATQSPISKKRKKKGFLPETK
KRKKRKSEDGMLAE-----------DGTPAATGGSQP--PSMGRKRRNRT--KA------
------------------------------------------------------------
----------------------KVPAQ--ANGTPA-TKSPAPGTP---------------
----------------------------------------------------TLSPSTP-
AKSPELQRKSQKPSQVNGA-PRS---PVEPAGQKQHQKALPKKGVLGKSPL---SAPARR
KAR--LSLVIRSPSLLQSGAKKKK--AQ-L--RKAGKP-

---------------------------------------------------------MES
RDVAEPMSLGEATKSGARPADPHGLLKHSREFLDFFWDIAKPQQETRLEATEKLLEYLRT
RPQGS-EMKYALKRLITGLGVGRETARPCYSLALAQLLQSFEDIPLCSILQQIQEKHDLQ
KVKKTMMRPALFANLFGVLALFQSGRLVKDSEALMKSVKLLQTLAQYYNHLQEQPQQALV
DILSEVPEATLQEVLPKVLR-ADLNSVLGSPEHLQLFLLAQQKVP-----TELEKLMGSV
NLFSDENIPRLVTVLKMAAASVKKERRLPTVALDLLRLALQEDKFPRFWK-EVVEQGLLK
KHFWPASYLCFRLLGAALPLLSKEQLQLVMRGDLIRQYGEHLVTAKFPNQFKFAPEMNEY
VGAFLEGCRDDPERQLAVVVAFTSITNQGLPVVPTFWRVVQSLS--APAL----------
--KGYVAWLRDMFLQPDLESLVDFSTNNQKKAQDASL-----HGPERAVFRLRKWIILRL
VSI-VDNVHVEKEEALIEEVARFCFFHAFFETKKPTPQIPETEQRFSFPLESRAREVVSG
AFFSLLQTLSTQ-------------FRQAPEQTRDGQPWTYRLVQFADMLLNHSR-NVAA
LTPF-TPPQRQAWDRMLQTLKELEARSSEA-KAKAAAFQHLILLVGIHLFKS------PA
ESCDLLGDIQTCIKKSLGEKTR-RTRS---KAVNPQEPPWVEVLVEILLALLAQPSHLMR
QVARSVFSHICSHLTPRALQLILDVLNPEKSQDED-DNVVVMDDSE-KQLENV-----ED
KSED-----SEDNKNSEDEEYSD--EEESDEEDRDGD-VDQGFREQLMAVLQAGKALGGV
DSEDD---DEELGDEAMMALDQNLASLFAEQKLRIQARKDEKNKLQKEKMLRR-DFQIRV
LDLIEVLVTKQPENPLVLELLEPLLNIIRRSMRTS----STKQE---QDLLHKTARIFTH
HLCRSRHYCHDVGNYMETLYSQVERLVQQAGHQADSSISLYYFNASLYLLRVLKGNSAHG
SVHKTQRKEEAGLDAS---------------------------------------TKPRG
PE----------------APSSFDLSLVTPIYSSALSSFLTKRNSPLTVPMFLSLFSRH-
------------------------------PALCKSLLPVMV-------QHVTGQTRPRH
Q--ACLLLQKTLPTRELRLC----FEDPEWEQLIGQILAKVTEN----------------
--------------------------LRTLGEAQTKSEQQRELSSVELLNVLF---RTVH
QENLTTDLTAVRGVLQSRQA-------RLQQGERA--TGSGRLHNL-----YWQAMKTLG
VQ-R----------------------PKSEKKDVKE-VPSATQSPVSMKRKKKGFLPETK
KRKKRKSEGTMQQD-----------ATKPAVTSGNQP--PSTGRKRRNRV--KA------
------------------------------------------------------------
----------------------KFPAQSQVNGTPA-TKSPAPDPP---------------
----------------------------------------------------ATSPSTP-
AKTPKLQKKNRKLSQVNGATPVS---PTEPAK-KEHQKALPKECVSGKSPQ---STLPRK
KAR--VSLASRSPSLLQSGAKKKKVQLRKGRKP------

------------------------------------------------------MAVKKG
PGVAEAAPPSEAT-----SADRHGLLEHSREFLDFFWDIAKPEQETRLEATEKLLAYLRA
RPE-GSEMKYALKRLITGLGVGREAARPCYSVALAQLLQSFEDIPLCSILEQVQEKYELH
TVKKAMIRPALFANLFGVLALFQSGRLVKDQKALMKSVKLLQVLSHHYNHLQGQPMQALV
DILSEVPETMFEEILPKILK-ADLNIVLSSPKHLELFLLSYQKVP-----AKLESLMGAV
DLFKDENIPRLVNVLKSAATSVKKENKLPNVALDLLRLALKEDKFLWFWK-EIVEQGLLT
KPSRPTSFLCFRLLGAALPLLSKEQLQLVMQGDLARHFGEHMVTAKLSNQSKFVPEMSAY
VGTFLEGCQADPERQVLVLVAFSSITNQGLPIMPTFWRVTRFLS--PQAL----------
--QDYVAWLQGMFLQPNLDALVDFSTTNQKRVQDASF-----NAPERAVLRLRKWIIHRL
VSL-LDTLHLEKEEALVEQVARFCLFHAFFKTKKPTSQIPETKQQFSIPMDTRTREFFTS
AFFSLLQTLSTK-------------FRHTPDQPQGGQPWIYRLVHLADTLLNHSR-NVAV
VTPF-TTQQRKAWDQMLETLKELEARSSEA-K--ATAFQHLLLLVGIHLFKS------PA
ESCDLLGDIQTCIKKSMGEKTR-RSRS---KATSSQEPPWVEVMVEILLSLLSQPSNLMR
HVARSVFGHICSHVTPRALQLILNVLNPEENQDED-DAVVITDDSDEKQVEDE-----ED
QGSD-----SEDK-NSESEV-D-SEGEESEEEERDEH-VDPGFRHQLMEVLQARKALGGV
DSDE---DEEELSDEAMMALDESLSSLFAEQRLRIQARRDEKNKLQKEKALRR-DFQIRV
LDLIEVLVTRQPENPLILELLEPLLNIIRNSMRSNS---SSKQE---QDLLHKTARIFMH
HLCRARHYCQDVGHCSAALHAQVERLVRQASQQADSSVALYYFNASLYLLRVLKGNATKK
HMLESQQWQGAGASLG---------------------------------------PEETG
P---------------Q-TSSCLDLDLVTPLYLAALSSFLTKRNSPLTVPMFLSLFSRY-
------------------------------PVICKNLLPVVV-------QHMAGSTRARQ
QTQACLLLQKTLSARELRMC----FEDPEWEQLIGQILTKVTEN----------------
--------------------------LCTLGEAQSRSEHQKQLSSLELLNTLF---KMIN
HEKLTVDLTTLLGVLQGQQQ---SLQQSLQQGERS--AGSSRLCDL-----YWQAMKMLG
VQ-----------------------RPKMEKKNTKA-VPNASESPISMKRKKKGFLPETK
KRKKRKLEEATPEEGAT------PKGAT-PATGDDQPPST--GKKKRKRMKTKVLAQSQV
DGTPATPA----------------------------------------------------
------------------------------------AKSPGPDTL---------------
----------------------------------------------------TLSPSTP-
AKTPKLQK-K---------------------------SRKLSQGISGKS---PQSALSRK
RAR--LSLV-RSPSLFQSGAKKKKLLRKKLKTP------

---------------------------------------------------------MES
RDPAEPMSPGEATQSDARPADRYGLLKHSREFLDFFWDIAKPEQETRLAATEKLLEYLRG
RPKGS-EMKYALKRLITGLGVGRETARPCYSLALAQLLQSFEDLPLCSILQQIQEKYDLH
QVKKAMLRPALFANLFGVLALFQSGRLVKDQEALMKSVKLLQALAQYQNHLQEQPRKALV
DILSEVSKATLQEILPEVLK-ADLNIILSSPEQLELFLLAQQKVP-----SELKKLVGSV
KLFSDENVPRLVNVLKMAAASVKKDRKLPAIALDLLRLALKEDKFSRFWK-EVVEQGLLK
MQFWPASYLCFRLLGAALPLLTKEQLQLVMRGDVIRHYGEHVCTAKLPKQFKFAPEMDDY
VGTFLEGCQDDPERQLAVLVAFSSVTNQGLPVTPTFWRVVRFLS--PPAL----------
--QGYVAWLRAMFLQPDLDSLVDFSTNNQKKAQDSSL-----HMPERAVFRLRKWIIFRL
VSI-VDSLHLEMEEALTEQVARFCLFHSFFVTKKPTSQIPETKHPFSFPLENQAREAVSS
AFFSLLQTLSTQ-------------FKQAPGQTQGGQPWTYHLVKFADLLLNHSH-NVTT
VTPF-TAQQRQAWDRMLQTLKELEAHSAEA-R--AAAFQHLLLLVGIHLLK---------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------------V
LDLVEVLVTKQPENALVLELLEPLLSIIRRSLRSS----SSKQE---QDLLHKTARIFTH
HLCRARRYCHDLGERAEALHAQVERLVQQAGRQPDSPTALYHFNASLYLLRVLKGNTAEG
CVHETQEKQKAGTDPS---------------------------------------PMPTG
PQ----------------AASCLDLNLVTRVYSTALSSFLTKRNSPLTVPMFLSLFSRH-
------------------------------PVLCQSLLPILV-------QHVTGPVRPRH
Q--ACLLLQKTLSMREVRSC----FEDPEWKQLMGQVLAKVTEN----------------
--------------------------LRVLGEAQTKAQHQQALSSLELLNVLF---RTCK
HEKLTLDLTVLLGVLQGQQQ-------SLQQGAHS--TGSSRLHDL-----YWQAMKTLG
VQR-----------------------PKLEKKDAKE-VPSATQSPISKKRKKKGFLPETK
KRKKRKSEDGTPAE-----------DGTPAATGGSQP--PSMGRKKRNRT--KA------
------------------------------------------------------------
----------------------KVPAQ--ANGTPT-TKSPAPGAP---------------
----------------------------------------------------TLSPSTP-
AKSPKLQKKNQKPSQVNGA-PGS---PTEPAGQKQHQKALPKKGVLGKSPL---SALARK
KAR--LSLVIRSPSLLQSGAKKKKAQTLRF--TISSSKK

---------------------------------------------------------MES
RVPSESASPGGAATSGPRPADREGLLQQSREFLDFFWDIAKPEQETRLEATEKLLAYLRA
RPQGP-ERKYALKRLITGLGVGRETARPCYSLALAQLLQSFEDIPLCSVLQQIQEKHDLQ
KVKKAMMRPALFANLFGVLALFQSGRLVKDSEALLKSVKLLQNLAQHHNHLQEQPQKALV
DILSEVPAATLQAILPKVLK-ADLNSVLGSPEHLQLFLLAQQKVP-----EKLKELIGPV
NLFSDENIPRLVNVLKTAAASVKKERKLPAVALDLLRLSLQEGKFPRFWK-EVVEQGLLK
KQFWPASYLCFRLLGAALPLLSEEQLPLVMQGDLIRHFGEHMVTAKLPKQFKFAPEMNEY
VGAFLEGCRDDPERQLAVVVAFTRITNQGLPVLPTFWRVVRSLS--PRAL----------
--KGYVAWLQTTFLQPDLDSLVDFSTSNQKKAQDASL-----HGPERAVFRLRKWVILRL
VST-VDALHAEKEDDLIEEVARFCFFHSFFETKKPTSQIPETEQQFSFPLESRTREVVSS
AFFSLLQTVSTQ-------------FRLAPARTPDGQPWTHRLVQFADLLLNHSR-NVTP
LTPF-TTQQRQAWDRMLQTLKELEACSAEA-KAKASAFQHLLFLVGIYLFKS------PA
DSCELLADIQTCIQKSLGEKPR-RTRS---KAATPQEPPWVEVLVEILLALLAQPSHLMR
QVARTVFSHVCVHLTPRALQLILDVLNPEKSADED--NVVVTDDSE-KQSESG-----ED
KSSD-----SEDDRPSASEDDSD--DEDSNEEDRDGD-VDQGFREQLMAVLQAGKALGAV
DGEDDG--DEELGDEAMMALDENLASLFAEQKLRIQARRDEKNKLRKEKVLRR-DFQIRV
LDLIEVLVTKQPENPLVLELLEPLLDVIRRSMRTS----SSKQE---QDLLHKTARIFTH
HLCRSRHYCHDVGRGVGALYAQVERLVQQAGRQVDASLSLYYFNAALYLLRVLKGNSTAA
TVCKPQKKEKAGP-------------------------------------------KPGG
PK----------------ASGGLDLSLVTPIFSSALTSFLTKRNSPLTVPMFLSLFSRH-
------------------------------PVLCKSLLPVVI-------QHVTGQARPRH
QAQACVLLQKALPTRELRLC----FEDPEWEQLVSQILVKVTEN----------------
--------------------------LRTLGEAQSKSEQQQELSSLGLLNTLL---RTVH
QEKLTVDLTGVLGVLQSQQQ-------RLLPGGDS--ASCSRLCNL-----YWQAMKALG
VQ-R----------------------PKSEKKEARE-VPKVMQSPLSTKRKKKGFLPETK
KRKKQTLEGAALVE-----------EAKPTTSGGDQP--PSTGKRRRRKR--KA------
------------------------------------------------------------
----------------------QGSTQANGTPATK---RPAPEAM---------------
----------------------------------------------------T--PSAP-
AKTPKLQ-EKQQPSQVNGARPAS---PAAPAGRKQPQKDLPEKGVSGKSPQ---SALPRK
KAR--LSLASRSPTLLQSGAKRKKASLKKARKP------

------------------------------------------------------MAEMES
QDVAEPVSPGEATKSGAPPADRHGLLQHSREFLDFFWDIAKPEQETRLEATEKLLEYLRT
RPKGS-EMKYALMRLITGLGVGRETARPCYSLALAQLLQSFEDIPLCSILEQIKEKYNLQ
KVKKAMVRPALFAHLFGVLALFQSGRLVKDQEALMKSVKLLQVLTQHHNHLQEQPQKALV
DILSEVPEATLKDILPKVLK-SDLGVVLSSPEYLELFLLAQQKVP-----AKLEKLLGSV
DLFSDENIPRLVNVLKMAAASVKKERKLPAVALDLLRLALQENKFPRFWN-EVLEQGLLK
KQFLPASFLCFRLLGAALPLLSKKQLQLVMRGDVIHHYGEHLVTSKAPDRFKFAPEMDEY
VGTFLEGCKTDPERQLAVLVAFSSITNQGHPVVPTFWRVVQFLS--PCAL----------
--KDYVAWLRDMFLQPNLDSLVDFSTSNQKKNQDASL-----HVPERAVFRLRKWIILRL
VSI-VENSQVEKEEALVEEVARFCLFHSFFETKKPTSQIPETEQRLSFPLESRTREVVCS
AFFSLLQALSTQ-------------FRQVPGQTQGGQPWTYRLVQFTDMLLNHNR-NVTT
TTPF-TAQQRQAWDRMLQTLKELEAHSTEV-K--ATAFQHLLLLVGIHLFKS------PA
ESCDLLGDIQTCIEKSLEGKPR-RTRS---KAVDSQEPPWVEVLVEILLALLAQPSHLMR
QVARSVFGHICSHLTPRALQLILDVLNPDKSQDED-DNVVVMDDSDDKQVMMK-----TA
QVLAGGQ----GG------------AAAAGRHVRDKD-VDQGFREQLMAVLQAGKALGGV
DSEDE---EEELGDEAMMALDQNLASLFAEQKLRIQAKKDEKSKLQKEKVLRR-DFQIRV
LDLVEVLVTKQPENSLVLELLEPLLTVIRRSMRTS----SSKQE---QDLLHKTARIFTH
HLCRARHYCHDVSNHVEALHTQVERLVQQASRQADSSVALYYFNATLYLLRVLKGNPADA
LPLKTPKKQKASA-------------------------------------------KAKA
PQ----------------ATSCLDLKRVTMVYSSALSSFLTKRNSPLTVPMFLSLFCRH-
------------------------------PVLCKSLLPIVV-------QHVTGPARPRQ
QAQACLLLQKALSMGELRPC----FEHSEWEQLIGQVLAKVTE-----------------
---------------------------RTLGKAQTKSEQQRELSSLELLITVL---KTIH
LQKLTLDLTTILGLLQGLQP---SLQQSLQQGAHL--AGSSRLYDL-----YWQAMKFLG
VQR-----------------------PKSEKKDAKK-IPSDTQSPVSMKRKKKGFLPETK
KRKKRKPEDATEQ------------DAKPATPGEKQP--PSSGKKKRHRR--KA------
------------------------------------------------------------
----------------------AASAQSQVNGKPA-AK----------------------
----------------------------------------------------SSAPSSP-
AKTPKLRKKHQKLSQMNGTART-------ESAGKKLQKSLPKKGASGKSPQ---PTLLQK
KAR--LSLADGSPSLLRSGAKRKKVQLKKGVQP------

------------------------------------------------------MAEPAS
MEVTEPLAPGEAQKSGVRPADRHGLLKHSREFLDFFWDIAKPQQETRLEATEKLLEYLRA
KPKGSSEMKYALKRLITGLGGGREAARPCYSLALAQLLQSFEDIPLGSILQQIQEKHDLQ
KVKKGMMRPALFGNLFGVLALFQSGRLVKDSEALMKSVKLLQALGQHYNHLQEQPQKALV
DILSQVPEAALQEILPKVLK-PDLNSVLGSPEHLELFLLAQQKVP-----EKLEKLMGPV
NLFSDENIPRLVTVLKTVANSVKKERKLPTVALDLLRLALQEDKFPWFWK-EVVEQGLLK
KQFWPASYLCFRLLGAALPLLSKEQLQLVMQGDLIRHYGEHMVTAKLPKQFKFAPEMNEY
VGAFLEGCRGDPERQLALVVAFTSITNQGLPVVPTFWRVVQFLS--PTAL----------
--KGYVAWLQDMFLQPDLDSLVDFSTNNQKKTQDTSF-----HGPERAVFRLRKWIILRL
VSI-VDNLHVEKEEALIEEVARFCFFHSFFETKKPTSQIPESEQHFTLPLDGRTREVVCG
AFFSLLQTLSTQ-------------FRLAPEQTADGRPWTYHLVQFADVLLNHSR-NVAP
LTAF-TTQQRQAWDRMLKTLKELDTLSSEA---KATAFQHLLLLVGIHLFKS------PA
ESCDLLGDIQTCIKKSLGEKTR-RTRS---KATNPQEPPWVEVLVEILLSLLAQPSHLMR
QVARSVFGHICAHLTLRALQLILDVLNPEESQDED-DNVVVTDDSEEQLLGGA-----ED
KSSDGEDSKGSKV--SES--EEESDDDDSDEEDRDGD-VDQGFREQLMAVLQAGKALGGA
DSEDD-NDDEELGDEAMMALDKSLASLFAEQKLRIQARKDEKNKLQKEKALRR-DFQIRV
LDLIEVLVTKQPENPLVLELLEPLLLVIRRSMRSNS---SAKQE---QDLLHKTARIFTH
HLCRSRHYCRTAGDRVETLYARLERLVQQAGQQADSSVALYHFNASLYLLRVLRGSTVDK
PARKAQKKEKASKD---------------------------------------AS-----
-----------SQPQGPEAASCLDLSLVTPIYSSALSSFLTKRNSPLTVPMFLSLFSRH-
------------------------------PMLCKSLLPIVV-------EHVTSHTRPRH
QVQACLLLQKTLPTRELRVC----FKDPEWKQLMGQTLGKVTEI----------------
--------------------------LRTLGEAETKSGHQKDLAALELLNTLF---RNFH
HEKLTMDLTAVLGVLQSQQL---RLQQRLQQGEHS--AGSSRLHDL-----YWQAMKFLG
VQR-----------------------PKSEKDTKEA-PQATQQSPVSMKRKKKGFLPETK
KRKKHKPEATTQEA----------AAAKPEATSGDQPPSA--GKKKKKKKKMKKT-----
------------------------------------------------------------
----------------------KSPALSQMNGTPA-AKSPTPEPP---------------
----------------------------------------------------AVSPSTP-
TKTPKPQKKTQKLAQVNEATPLPHQSPEEPVAKKRQ-KKLPQKGVSGKSPQ---SALPRK
KAR--LSLAIRSPSLLQSGAKKV-QL-RKAKK--L----

---------------------------------------------------------TES
TDVAEPPAPGEAPKSGARPVDRHGLLKHSREFLDFFWDIAKPQQETRLEATEKLLEYLRA
RPEGSSELKYSLKRLITGLGVGRETARPCYSLALAQLLQAFEDIPLCSILQQIQEKYDLQ
KVKKGMVRPALFGNLFGVLALFQSGRLVKDSEALMQSVKLLQILGQHYSHLQEQPQKALV
DILSQVPEAMLQEVLPKVLK-PDLNSVLGSPEHLELFLLAQQKVP-----KKLEKLMGPV
NLFSDESIPRLVTVLKMAATSVKKERKLPAVALDLLRLALQEDSFPRFWK-EVVEQGLLK
KQFWPASYLCFRLLGAALPLLSKEQLQLVMQGDLIRHYGEHMVTAKLPSQFKFAPEMNEY
VGAFLKGCQDDPERQLALVVGFTSVTNQGLPVVPTFWRVTQFLS--LPAL----------
--KGYVAWLRDMFLQPNLDSLVDFSTNNQKKAQDALF-----HGPERAVFRLRKWLIFRL
VSI-VDNLHAEKEETLIEEVARFCFFHSFFETKKPMSQIPETEQHFSHPLDSRTREVVGS
AFFSLLQTLSTQ-------------FRQAPGQTQDGQPWTYHLVRFADLLLSHSR-NVVP
LVAF-TTQQRQAWDRTLKTLKELEAQSSEA---KATAFQHLLLLVGIHLFKS------PT
ESCDLLGDIQTCIKKSLGEKPR-RTRS---KATNPQEPPWVEVLLEILLALLAQPSHLMR
QVARSVFSHICSHLTPRALQLILDVLNPEESQNED-DNVVVTDASERQLLGDA-----ED
ESSDDGEDKGNED--SES-DEEESSDEESDEEERDGD-VDQGFREQLRAVLQAGKALGGA
DGED----DDELGDEAMMALDKNLASLFAEQKLRIQARRDEKNKLQKEKALRR-GFQIRV
LDLIEVLVTKQPENPLVLEVLEPLLHVIRRSMRT-S---SAKQE---QDLLHKTARIFXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----XXXXXXXXXXXXXXXXXXXX-
-X-XXXXXXXXXXXXXXX--------------------------XXXX-----XXXXXX-
-----------XXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------XXXXXXXXXXXX-
------------------------------XXXXXXXXXXXX-------XXXXXXXXXXX
XXXACLLLQKTLPTRELRLC----FKDPEWEQLLDQILAKVTET----------------
--------------------------LRTLGEAETKSGRQKELSSLELLNVLF---RNIH
HEKLTMDLTAVLGVLQSQQP---RLQQGLQQGAHS--AGSSRLYDL-----YWQAMKFLG
VQR-----------------------PKSEKKDAKE-VPKATPSPISMKRKKKGFLPETK
KRKKRKSEGATQEE-----------AAKPSAAGGDQPPST--GKRKRKIKH---------
------------------------------------------------------------
----------------------KGPAQSQAQGLPA-SKSPTPEPP---------------
----------------------------------------------------ATSPSSP-
AKTPKPQKKNRKLSQVSRATPVSPESPKEPCQR---QKNLPQKGVSGKSPQ---SALPRR
KAR--LSLASRSPSLLQSGVKKKGQT-LRFTV--SSSKK

---------------------------------------------------------MGS
RELAERMSPGEATQSGARPADRHGLLKHSREFLDFFWDIAKPEQETRLAATEKLLEYLRG
RPKGS-EMKYALKRLITGLGVARETARPCYSLALAQLLQSFEDLPLCSILQQIQEKYDLH
QVKKTMLRPALFANLFGVLALFQSGRLVKDQEALMKSVKLLQALAQYQNHLQEQPRKALV
DILSEVSVATLQEILPEVLK-ADLNTILSSPEQLELFLLAQQKVP-----SKLKKLVGSV
DLFSNENVPRLVNVLKMAASSVKKDRKLPAIALDLLCLALKEDKFPRFWK-EVVEQGLLK
MQFWPASYLCFRLLGAALPLLNKEQLQLVLRGDVIRHYGEHVCTAKLPKQFKFAPEMEDY
VGTFLEGCQDDPERQLAVLVAFSSVTNQGLPVAPTFWRVVRFLS--PPAL----------
--QGYVAWLREMFLQPDLDSLVDFSTNNQKKAQDASL-----HVPERAVFRLRKWIIFRL
VSI-VDSLHLEMDEALTAQVARFCLFHAFFVTKKPTSQIPETKQPFSFPLESQAREAASS
AFFSLLQTLSTQ-------------LKQAPDQTRGGQPWTYHLVQFADLLLNHSH-NVTT
VTPF-SAQQRQAWDRMLQTLKELEAHSSEA-R--AAAFQHLLLLVGIHLLKP------AS
SQGEHPSGHLAALA----------------------------------------------
----GVLGSPCR------------------------------------------------
-----------------------------------ISC-NLHSFEQLMSVLQAGKALGGE
DSEDE----EELGDEAMMALDQSLASLFAEQKLRVQARRDEKNKLQKEKALRR-DFQIRV
LDLVEVLVTKQPENALVLELLEPLLSIIRRSLRSS----NSKQE---QDLLHKTARIFTH
HLCRARRYCHDLGERAEALHAQVERLVQQAGRQPDSPTALYHFNASLYLLRVLKGNTAEG
CVRETREKQKAGTDPS---------------------------------------PMPTG
PQ--GPTL---SLLEGGQAASCLDLNLVTRVYSSALSSFLTKRNSPLTVPMFLSLFSRH-
------------------------------PVLCKSLLPILV-------QHVTGPVRPRH
Q--ACLLLQKTLSMREVRSC----FEDPEWKQLMGQVLAKVTEN----------------
--------------------------LCVLGEAQTKAEHQQALSSLELLNTLF---RTCK
QEKLTLDLTVLLGVLQGQQQ-------SLQQGAHS--TGSSRLHDL-----YWQAMKTLG
VQR-----------------------PKLEKKGAKE-VPSATQSPISKKRKKKGFLPETK
KRKKRKSEDGTLAE-----------DGTPAATGGSQP--PSMGRKKRNRT--KA------
------------------------------------------------------------
----------------------KVPAQ--ANRMPA-TKSPAPGTP---------------
----------------------------------------------------TLSPSTP-
AKSPELQKKNQKPSQVNGA-PRS---AVEPAGQKQHQKALPKKGVLGKSPL---SAPARK
KAR--LSLVIRSPSLLQSGAKKKKTLRFTI--S--SPKK

---------------------------------------------------------MES
RDPAQPMSPGEATQSGARPADRYGLLKHSREFLDFFWDIAKPEQETRLAATEKLLEYLRG
RPKGS-EMKYALKRLITGLGVGRETARPCYSLALAQLLQSFEDLPLCSILQQIQEKYDLH
QVKKAMLRPALFANLFGVLALFQSGRLVKDQEALMKSVKLLQALAQYQNHLQEQPRKALV
DILSEVSKATLQEILPEVLK-ADLNIILSSPEQLELFLLAQQKVP-----SKLKKLVGSV
NLFSDENVPRLVNVLKMAASSVKKDRKLPAIALDLLRLALKEDKFPRFWK-EVVEQGLLK
MQFWPASYLCFRLLGAALPLLTKEQLHLVMQGDVIRHYGEHVCTAKLPKQFKFAPEMDDY
VGTFLEGCQDDPERQLAVLVAFSSVTNQGLPVTPTFWRVVRFLS--PPAL----------
--QGYVAWLRAMFLQPDLDSLVDFSTNNQKKAQDSSL-----HMPERAVFRLRKWIIFRL
VSI-VDSLHLEMEEALTEQVARFCLFHSFFVTKKPTSQIPETKHPFSFPLENQAREAVSS
AFFSLLQTLSTQ-------------FKQAPGQTQGGQPWTYHLVQFADLLLNHSH-NVTT
VTPF-TAQQRQAWDRMLQTLKELEAHSAEA-R--AAAFQHLLLLVGIHLLKS------PA
ESCDLLGDIQTCIRKSLGEKPR-RSRT---KTIDPQEPPWVEVLVEILLALLAQPSHLMR
QVARSVFGHICSHLTPRALQLILDVLNPETSEDEN-DRVVVTDDSDERRLKGA-----ED
KSEE-----GEDNRSSESEEESE--GEESEEEERDGDV-DQGFREQLMTVLQAGKALGGE
DSENE----EELGDEAMMALDQSLASLFAEQKLRIQARRDEKNKLQKEKALRR-DFQIRV
LDLVEVLVTKQPENALVLELLEPLLSIIRRSLRSS----SSKQE---QDLLHKTARIFTH
HLCRARRYCHDLGERAGALHAQVERLVQQAGRQPDSPTALYHFNASLYLLRVLKGNTAEG
CVHETQEKQKAGTDPS---------------------------------------HMPTG
PQ----------------AASCLDLNLVTRVYSTALSSFLTKRNSPLTVPMFLSLFSRH-
------------------------------PVLCQSLLPILV-------QHITGPVRPRH
Q--ACLLLQKTLSMREVRSC----FEDPEWKQLMGQVLAKVTEN----------------
--------------------------LRVLGEAQTKAQHQQALSSLELLNVLF---RTCK
HEKLTLDLTVLLGVLQGQQQ-------SLQQGAHS--TGSSRLHDL-----YWQAMKTLG
VQR-----------------------PKLEKKDAKE-IPSATQSPISKKRKKKGFLPETK
KRKKRKSEDGTPAE-----------DGTPAATGGSQP--PSMGRKKRNRT--KA------
------------------------------------------------------------
----------------------KVPAQ--ANGTPT-TKSPAPGAP---------------
----------------------------------------------------TRSPSTP-
AKSPKLQKKNQKPSQVNGA-PGS---PTEPAGQKQHQKALPKKGVLGKSPL---SALARK
KAR--LSLVIRSPSLLQSGAKKKA-QTLRF--TISSSKK

------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------PLWASPP------
----------------LPLPLTAQLPPPQDPKALVACVQLLQSLAQHRNHLQDLPRRTLV
DIVAEIPEPVFEEVLLGVLQ-ADLAAAFSTPEQLQLLLVGLQKFPGVLQPKKLKKLLGSA
SVVTKETVPRLVEVLQAAAKSVKKEKVLPPVGLDLLRVALQEGAFELFWK-GVVEKGLLE
EHSGPGSYTAFRLLGSVLPLLSLEQLQVVLRGEVMRRYGDHVLSAQLPSRFKFAPEMEKY
VDSFLEGC-PDPEKQLAVLVAFSSLTNQGYPVVPSLWPVVRHLQ--PEAL----------
--ERYCKWLRDMFLRPDLGRCLXXXXHPTKKARARVRRRACGDAREVRVPLPQ-VAHSEA
EQHRGERP-GGKGRGLRHGHSQVL-LLPFLL-----------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------MAEMKS
PTKAEPASPAEAP-----QGDRRSLLEHSREFLDFFWDIAKPDQETRLRATEKLLEYLRT
RPS-DSEMKYALKRLITGLGVGREAARPCYSLALAQLLQSFEDIQLCDILGQIQEKYNLQ
AMNKAMMRPTLFANLFGVLALFQSGRLVKDKEALMKCVRLLKILSHHYNHLQGQPVKALV
DILSEVPESMFQEILPKVLK-GDMKVILSSPKYLELFLLARQRVP-----AELESLVGSV
DLFSEDNIPSLVNILKVAANSVKKEQKLPDVALNLLRLALQENKFERFWK-EVLEEGLLK
KPSYTSSYMCFRLLGASLPLLSDEQLQLVMRGDLIRHFGEHMVVSKSQNPLRFIPEISAY
VGTFLEGCQDDPKRQFTVMVAFTAITNQGLPVMPTFWRVTRFLN--TEAL----------
--QNYVTWLRDMFLQPDLDSLVDFSTANQKRVQVASL-----NVPERTVFRLRKWIIHRL
VSL-VDHLHLEKDEAVVEQIARFCLFHAFFKTKKATPQIPETKQHFSFPLEDGNRGVIVS
AFFSLLQTLSVK-------------FRQTPDLAENGKPWTYRLVQLADMLLKHNR-NVAN
VTPL-TAQQRQAWDQMMSTLKELEAQSSET-R--AIAFQHLLLLVGLHLFKS------PA
ESCDVLGDIQTCIKKSMEQNLR-RSRS---RAKASQEPVWVEVMVEILLSLLAQPSNLMR
QVVRSVFGHVCSHLTPRGLQLILAVLNPETNEDEE-DNVVVTD-TDEKQLKHG-----ED
ADSD-----SEDSKNSESDVDS-EDGEESEEEDRDKD-VDPGFRQQLMEVLQAGNALGGE
E---E--EEEELGDEAMMALDQNLASLFAEQKMRIQARHEEKNKLQKEKQLRR-DFQIRA
LDLIEVLVTKQPEHPLILELLEPLLNIIQRSMRSRG---STKQE---QDLLHKTARIFMH
HLCRARHYCHEVEPGAEALHAQVERLVQQAGNQADASVALYYFNASLYLLRVLKGNTTKR
YQ-DGQKLEGADIKSE---------------------------------------PKDSE
V---------------Q-TTSCLDLDFVTRVYSASLESLLTKRNSPLTIPMFLDLFSRY-
------------------------------PVICKNLLPIVV-------QHVAGSSRPRH
QAQACLLLQKALSARELRVC----FEDPEWEQLISQVLGKTTQT----------------
--------------------------LQTLGEAQSKGEHQRELSILELLNTVF---RIVN
HEKLSVDLTAFLGMLQGKQQ---KLQQNLQQGNHS--SGSSRLYDL-----YWQAMNLLG
VQ-----------------------RPKSEKKNVKD-IPSDSQSPISTKRKKKGFLPETK
KRKKLKSEGTTSEKKAASQQDAVTEGAMPAATGKDQPPST--GKKRRKR--VKANTPSQV
NGVTV-------------------------------------------------------
------------------------------------AKSPAPNNP---------------
----------------------------------------------------TLSPSTPP
AKTPKVQKKKEKLSQVNGSTPVS---PVEPESKKH-QKALSTKEVKRR--S-SQSALPKK
RAR--LSLVSRSPSLLQSGIRKRRVARRRVQTP------

---------------------------------------------------------MGS
REPAEPMSPGDAMQNSARPADRHGLLKHSREFLDFFWDIAKPEQETRLAATEKLLEYLRA
RPKGS-EMKYALKRLITGLGVGRETARPCYSLALAQLLQSFEDLPLCSILQQIQEKYDLH
QVKKAMVRPALFANLFGVLALFQSGRLVKDQEALRKSVKLLQALAQYQNHLQEQPRKALV
DILSEVSEATLQEMLPEVLS-TNLDAMLSCPEQLELFLLAQQKVP-----SRLKKLVGSV
NLFSDENVPRLVNVLKMAASSVKKERKLPAVALELLRLALKEDKFLRFWK-GVVEQGLLK
LQFWPASYLCFRLLGAALPLLTKEQLQLVMRGDVIRHYGEHTCTAKLPNQFKFAPEMEEY
VGTFLEGCRDDPERQLAVLVAFSSATNHGLPVVPTFWRVVRFLS--PRAL----------
--QGYVAWLQGMFLQPDLDSLIDLSTSSQKKAQDASL-----HVPERAVFRLRKWIILRL
VSL-VDSLHLEMEEALTEQVARFCLFHSFFITKKPTSQIPETRQQLSLPLESQAREAVSS
AFFSLLQTLSTQ-------------FKLAPEQTRGGQPWTYRLVQFADLLLNHSH-SVTP
VTPL-TAQQHQAWDRMLQTLKELEAASSEP-R--AAAFQHLLLLVGIHLFKV--------
LECDLLGHPD-LHQKSWGERRR-GSRT---KAIDPQEPPWVEVLVEILLALLAQPSHLIR
QVARSVFGHVCSHLTPRALQLILDVLNPETNENED-DHVVVTDESDERWLKAA-----ED
KSED-----G-ENRGSDSEDQSE--GEESEEEERDGD-VDQGFREQLMSVLQAGKALGGE
ESEDE----EELGDEAMMALDQSLASLFAEQKLRIQARRDEKSKLQKEKALRR-DFQIRV
LDLVEVLVTKQPENVLVLELLEPLLSIIRRSLRSS----SSKQE---QDLLHKTARIFTH
HLCRGRRYCRDLGDRVEALHGQVAQLVEQAGRQPDSSTALYHFNASLYLLRVLKGSTAEG
RVHETQEELEAGTNPS---------------------------------------PAPEG
P----------------QAAGCLDLNLAMRVYSSALSSFLTKRHSPLTVPMFLSLFSRH-
------------------------------PVLCKSLLPVLV-------QHVTGPGRPHQ
QAQACLLLQKTLSMREVRSC----FQDPEWKQLIGQVLTKVTEN----------------
--------------------------LRTLGEAQTKAEHQQALSSLELLNTVF---RTCK
HEKLTLDLTVLLGVLQRQQQ-------GLRQGAHS--TSSSRLLDL-----YWQAMKTLG
APQDPGG--------------GGCCPHWLEKKDTKE-IPSTTQSPISRKRKKKGFLPETK
KRKKHTSE-----------------DGTPAATGGSQS--SSTGRK-RNRT--KA------
------------------------------------------------------------
----------------------KVLAQ--ANGTPT-TKGPAPGTP---------------
----------------------------------------------------TLSPSTP-
AKSPKLRKKNQKLSQVNGA-PGS---STKPAGQKQPQEVLPKKGVLDKSSP---STLARK
KAR--PPLVIRSPSLLQSGAKKK--NTLRF--TISSSKK

------------------------------------------------------MAEMKS
PAKAETASPTEAA-----QDERRGLLEHSREFLDFFWDIAKPEQETRLQATEKLLEYLRT
RPS-GSEMNYALKRLITGLGVGRETARPCYSLALAQLLQSFEDIPLCSILDQVQEKYNLQ
TVNKGMRRPAVFANLFGVLALFQSGRLVKDQEALMKSVKLLKILSHHYNHLQGQPVKVLV
DILSQVPESMFQEILPKILKGGDLKVVLSSPKHLELFLLAQQRVP-----AKLESLMGSV
DLFSEENIPSLVNVLKTAANSVRKEHILPEVALDLLRLALKENKFTLFWK-EVLEQRLLN
KPCWSASYMCFRLLGASLPLLSEEQLRLVMRGDLIRHFGEHMVISKPQNLFKIIPEISTY
VSTFLEGCQDDPKRQFAMMVAFTSITNQGLPVMPTFWRVTRVLS--SEAV----------
--QSYVAWLRDMFLQPDLDSLVDFSTANQKRVQDASL-----TVPERSVFRLRKWIIHRL
VSL-VEHLHLEKDDAVIEQVARFCFFHAFFKTKKATPQIPETKQHFSFPLDDRNRSVNIG
AFFSLLQTLSMK-------------FRQTPDLDESGKPWAYRLVQLADMLLNHSR-NVTI
VTPF-TAQQRQAWDQMMSTLKELEARSSET-R--AVAFQHLLLLVGLHLFKS------PT
ESCDVLSDIQTCIKKSTEQNPR-RSRS---RAKAPQEPAWVEVMVEILLSLLSQPSNLMR
KVVRNVFGHICSHLTPRGLQLILAVLNPETNEDED-DNVVVTDDNNEKQPKHG-----ED
EDSD-----SEDNKNSDSDVDS-EDGAESEEEDRDKD-VDPGFRQQLMEVLQAGNALGGV
DSEE---EEEELGDEAMMALDQNLASLFAEQKLRIRARQEEKNKLQKEKQLRR-DFQIRV
LDLIEVLVTKQPEHPLILELLEPLLSIIQRSMRSKG---STKQE---QDLLHKTARIFMH
HLCRARHYCHEVGPCAKSLLAQVERLVQQAGNQADASLALYYFNASLYLLRVLKGNTAKR
YQ-DGQNLPEA----E---------------------------------------PKDSE
V---------------Q-TANCLDLDFVTRVYSAALESFLTKRNSPLTVPMFLSLFSRY-
------------------------------PVICKNLLPILV-------QHVAGPLRPRH
QAQACLLLQKTLSARELRVC----FEDPEWEQLIGQVLGKVTQT----------------
--------------------------LQTLGEAQSKGEQQREFSALELLNVLF---KTVN
HEKLSVDLTSVLGLLQSKQQ---KLQQSLQQGNHS--SGSNRLYDL-----YWQAMKMLG
VQ-----------------------RPKSEKKNVKD-IPSDSQSPVSMKRKKKGFLPETK
KRKKLKSEDTTPGKDATSGQDVVSADATPA-AGEGQPPST--GKKKRKR--AKASTPSQV
NGAPV-------------------------------------------------------
------------------------------------TKSPAPNNP---------------
----------------------------------------------------TLSPSTP-
FKSPKLQKKKEKLSQVNGATPVS---PIEPEGKKHHQKALPTKEVLRKS---PQSALPRK
RAR--LSLVSRSPSLLQSGVKKRKVARRKVQTP------

------------------------------------------------------MAEMRS
SVVDEPAPPGGAT-----SADRHGLLEHSREFLDFFWDIAKPHQQTRLEATEKLLAYLRA
RPE-GSEMKYALKRLITGLGVGREAARPCYSMALAQLLQSFEDIPLCSILEQVQEKYELN
TTKKAMIRPVLFANLFGVLALFQSGRLVKDQKALTKSVKLLQVLSHHYNHLQGQPLKALV
DILSEVPEAMFEEILPKVLK-PDLNVVLSSPKHLELFLLAYQKVP-----AKLKSWMGSV
DLFTDENLPKLVNVLRLAATSVKKENKLPNVALDLLRLVLKENQFLRFWK-EVVEQGLLT
KPSWPTSFMCFRLLGAALPLLSKEQLQLVMRGDLARHFGERMVTAKLSNQSKFVPEMSEY
MGTFLEGCQDDPERQLFMLVAFSSITNQGLPVMPTFWRVTRFLS--PQAL----------
--RDYVAWLQGMFLQPNLDSLVDFSTANQKKVQDASF-----NSPERAIFRLRKWIIHRL
VSL-LDTLHLEKEEALIEQVARFCLFHSFFKTKKPTSQIPETKQQFSSPVDSRTREFFTN
AFFSLLQTLSTK-------------SRHVPDQAQGGHPWIYRLVQLADTLLNHSR-NVAI
VTPF-TAQQRQAWDQMLETLKELEARSSET-K--ATAFQHLLLLVGIHLFKS------PT
ESCDLLGDIQTCIKKSMGEKTR-RSRS---KAINSQEPPWVEVMVEILLSLLSQPSNLMR
QVARSVFGHICSHLTPRALQLILKVLNPEASQDED-DAVVVTDDSDEKQLKDA-----ED
EGSD-----SKDE-NSESEV-D-SEGEESEEEERDEH-VDPGFRQQLMEVLQAGKALGGV
DSDE---DEQELSDEAMMALDESLSSLFAEQKLRIKARRDEKNKLQKEKALRR-DFQIRV
LDLIEVLVTRQPENPLVLELLEPLLNIIRSSMRSTSSSSSSKQE---QDLLHKTARIFMH
HLCRSRHYCHDVAHCAAELHTQVERLVRQAGQQADSSVALYYFNASLYLLRVLKGNANKK
HTPEGQQWEGDSAGGG---------------------------------------PEDPG
P---------------Q-TANCLDLDLVTPVYSAALNSFLTKRNSPFTVPMFLTLFSRY-
------------------------------PVICKSLLPILL-------QHMTGSARARQ
QAQACLLLQKTLSARELRAC----FEDPEWEQLIAQVLVKVTEN----------------
--------------------------LCTLGEAQSRSEHQKQLTSLELLNTLF---KITH
QEELTVDLTAVLGVLQGQQ-------QNLQQGERS--AGSNRLCDL-----YWQAMKTLG
VQ-----------------------RPKVEKKDAKE-VPSASESPVSVKRKKKGFLPETK
KRKKRKSEGPTPEERPA------PEGAARPATGGDQPPST--GKKKRKRMKAKVLAQPEV
NGTPA-------------------------------------------------------
------------------------------------TKSPAPDTL---------------
----------------------------------------------------ALSPSTK-
TPEL-EKK-SRRPSQANGDNAMP---ATEPSGKKQHQNALSKKGISGKS---PQSALLRK
RAR--LAVV-RSPSLFQSGAKRKKLLRKKLRTP------

------------------------------------------------------MAEMKS
PTKAEPASPAEAA-----QDDRRNLLEHSREFLDFFWDIAKPDQETRLRATEKLLDYLRT
RPS-DSEMKYALKRLITGLGVGREAARPCYSLALAQLLQSFEDIPLCDILGQIQEKYSLQ
AMNKAMMRPTLFANLFGVLALFQSGRLAKDKEALMKSVKLLKILSQHHNHLQGQPIKALV
DILSEVPESMFQEILPTVLK-GDMKVILGSPKYLELFLLAKRRIP-----TKLESLIGSV
DLFSEDNIPSLVNVLKVAANSAKKEHKLPNVALDLLRLALKENKLELFWK-KVLEEGLLK
TPSWTSSYMCFRLLGASLPLLSEEQLQMVMRGDLIRHFGENMVVSKPQNLFKIIPEISTY
VGTFLEGCQDDPKRQFTMIVAFTTITNQGLPVMPTFWRVTRFLN--AEAL----------
--QSYVAWLRDMFLQPDLDSLVDFSTTNQKRTQDASL-----NVPERTVFRLRKWIIHRL
VSL-VDHLHLEKDEAVVEQIARFCLFHAFFKTKKATPQIPETKQHFSFPLDDHTRGVIVS
AFFSLLQTLNVK-------------FRQTPDLAENGKPWTYRLVQLADMLLNHNR-NVTS
ATPL-TTPQRQAWDQMMSTLKELEARSSET-K--AIAFQHLLLLVGLHIFKS------PA
ESCDVLGDIQTCIKKSMEQNPR-RPRS---RAKASQEPVWVEVMVEILLSLLAQPSNLMR
QVVRSVFGHICSHLTPRGLQLILAVLNPVTNEDED-DNVVVTD---EKQLKHG-----ED
KDSD-----SEDNKNSESDMDS-EDGEESEEEDRDKD-VDPGFRQQLMEVLQAGNALGGV
DNEDD---EEELGDEAMMALDQNLASLFKEQKMRIQARNEEKNKLQKEKKLRR-DFQIRA
LDLIEVLVTKQPEHPLILELLEPLLNMIQHSMRSRG---STKQE---QDLLHKTARIFMH
HLCRARRYCHEVGSGAEALHAQVERLVQQAGSQADSSVALYYFNASLYLLRVLKGNTTKR
HQ-DGQKLNGADTQPE---------------------------------------PKDSE
D---------------Q-TANCLDLDFVTRVYSASLESLLTKRNSSLTVPMFLSLFSRY-
------------------------------PVICKNLLPILV-------QHVAGPSRPRH
QAQACLMLQKTLSARELRVC----FEDPEWEQLITQLLGKATQT----------------
--------------------------LQTLGEAQSKGEHQRELSILELLNTLF---RTVN
HEKLSVDLTAPLGVLQSKQQ---RLQQSLQQGNHS--SGSNRLYDH-----YWQAMRMLG
VQ-----------------------RPKSEKKNAKD-IPSDTQSPVSTKRKKKGFLPETK
KRKKLKSEGTTPEKNAASQQDAVTEGAMPATTGTDQPPST--GKKKRKR--VKASTPSQV
NGMTV-------------------------------------------------------
------------------------------------AKSLAPSNP---------------
----------------------------------------------------TLSPSTP-
AKTPKLQKKKEKLSQVNGSTPVS---PIEPESKKHHQKALEA---IRK--S-PLSALPKK
RAR--LSLLSRSPSLLQSGLKRRRVASRRAQTP------

---------------------------------------------------------MET
QE-PVEMAPGTDAKSGAQPDDHHSLLQHSREFLDFFWDIAKPEQETRLEATEKLLEYLRA
RPKGS-EMNYALKRLITGLGISRETARPCYCLALAQLLQSFEDIPLCSILQQIEEKHDLQ
KVKKAMMRAALFANLFGVLALFQSGRLVKDSEALMKSVKLLQVLAQHSNHLQEQPQKALV
DILSEVPKATLKEILPEVFK-GNLDSVLSSPEHLQLFLLAKQKVP-----VKLKELMGSV
NLFSDENIPRLVDALKMAAASVKKECTLPTVALNLLHLALKEDKFPRFWK-EVVEQGLLK
KQYWPASYLCFRLLGAALPLLSMEQLQLVLRGDLIQHYGQHMVTTKPSHQFKFAPEMEKY
MGAFLEGCRDDPDRQLAVVVAFTSITNQGLPVIPTTWRVVQFLS--GPAL----------
--KGYTAWLRDMFLQPDLDSLVDFSTNNQKKSHDTSF-----HGPGRAVFRLRKWIIFRL
VSI-VDNLHVEKEEVLIEEVARFCLFHSFFETKKPTSEIPETEQQFSFSMESSSRAVVSS
AFFRLLQTLSTQ-------------FRQMPGQTQDGRPWTYRLVRFSDV-LNHSR-NVVA
LTPF-TKPQHQA-DRMLQTLKKLKALSSEA-K--ATAFQHLLLLVGIHLFKS------PT
ESCDLLADIQTCIKKSLGESAH-RTRC---RATDSEEPSWVEVLVEILLALLAQPSHLIR
QVARSVFGHICSHLTPRALQLILDVLNPKKNQDEDEDNVVVTDDSKEKQLKNV-----ED
QSSD-----SEDR--------SSESEEESEEEDRDGE-VDQGFREQLMAVLQAGKALGGA
DSDED-EDDDALGDEAMMALDQNLSSLFAEQKLRIQARKDEKSKLQKEKVLRR-DFQIRV
LDLIEVLVTKQPENPLVLELLEPLLNMIRRSMRTS----STKQE---QELLHKTARIFTH
DLCRARHYCRDVGNDMEALYSRVERLVQQAAHQTDSCVSLYYFNASLYLLRVLKGSTI--
--QRIQGKEKAGTDAS---------------------------------------TKPTD
TE----------------ATSGLNLKLATPIYSFALNSFLTKRNSPLTIPMFISLFSRH-
------------------------------PVLCKSLLPVVT-------QHMTGPARPRH
Q--ACLLLQKTLPMRELRQC----FKDPDWKQLIGRILVKVTEN----------------
--------------------------LRALGKARSKSELQKELSSLELLNTLF---RSIN
QEKLTTDLTA-LGVLQSPQQ-------RLQQGEHP--AGSSRLYDL-----YWQAMKFLG
VQ-R----------------------PKSEKKDPRE-APTGTQNPVSLKRRKKGFLPETK
KRKKRKSEDATQ-E-----------EAKPVTTSGDQPPSTGKMK-KRNRM--KA------
------------------------------------------------------------
----------------------GGPAQSQVNGMPA---SKNPADS---------------
----------------------------------------------------SSHKSTP-
AKAPKLQKKKQKVSQVNGLTPTP---PTEPADKKQHQKALPPKEVSDQSPQ---SAQPRK
KAK--LSLPGKSPGLPQTGPKKEVHTLRF---TINSSKK

------------------------------------------------------MAVKKG
SEVAEPAPPGGAT-----SADRHGLLEHSREFLDFFWDIAKPQQQTRLEATEKLLTYLRA
RPEEGSEMKYALKRLITGLGVGREAARPCYSVALAQLLQSFEDIPLCSILEQVQEKYELH
TVKKAMIRPALFANLFGVLALFQSGRLVKDQKALMKSVKLLQVLSHHHNHLQGQPMQALV
DILSEVPEAMFEEILPKILK-ADLNVVLSSPKHLELFLLASQKVP-----AKLESLMGPV
DLFTDENIPRLVNVLKSAAPSVKKENKLPNVALDLLRLALKEDKFLWFWK-EVVEQGLLT
KPSWPTSFLCFRLLGTALPLLSKEQLQLVMQGDLARHFGEHMVTAKLSHQSKFVSEMSEY
VGTFLEGCQDDPERQLLVLVAFSSITNQGLPVMPTFWRVTRFLS--PQAL----------
--QDYVAWLQDMCLQPSLDSLIDFSTVNQKRVQDASF-----NTPERATFRLRKWIVHRL
VSL-LDTLHLEKEEALVEQVARFCLFHSFFKTKKPTSQIPETKQQFSFPVDSRTREFFTS
AFFSLLQILSTK-------------FRHIPDQAQGGQPWIYRLVQLADTLLNHSR-NVAI
VTPF-TTQQRQAWDQMLETLKELEACSSEA-K--ATAFQHLLLLVGIHLFKS------PT
ESCDLLGDIQTCIKKSMGEKTR-RSRS---KAISSQEPPWVEVMVEILLSLLSQPSNLMR
QVARSVFGHICSHLTPRALQLILNVLNPEENQDED-DAVVVTDDSDEKQLKDA-----ED
DGSD-----SKEE-NSESEV-D-SEGEESEEEERDEH-VDPGFRQQLMEVLQAGKALGEV
DSEE---DEEELSDEAMMALDESLSSLFAEQRLRLQARRDEKNKLQKEKALRR-DFQIRV
LDLIEVLVTRQPENPLILELLEPLLNIIRNSMRSSS--SSSKQE---QDLLHKTARIFMQ
HLCRARHYCHDMGHCAAALHTQVERLVRQAGQQADSSVALYYFNASLYLLRVLKGNATKK
HMLESQQCQGAGPNHG---------------------------------------PEDTS
P---------------Q-TASCLDLDLVTPVYLAALSSFLTKRNSPLTVPMFLSLFSRY-
------------------------------PVICKNLLPVLV-------QRMAGSTRARQ
QAQACLLLQKTLSARELRGC----FEDPEWEQLIGQVLAKVTEN----------------
--------------------------LCTLGEAQSRSEHQKQLSSLELLNTLF---KMIH
HEVSQQPAELGLGRSRHPEYSGLPGQEGDQQGPCG--EGSGCQCEDSELCVYMVFLPLDG
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------MAEMKS
PAKAESASPTETT-----QDERRGLLEHSREFLDFFWDIAKPEQETRLQATEKLLEYLRT
RPS-GSEMKYALKRLITGLGVGRETARPCYSLALAQLLQAFEDIPLCSILGQIQEKYNLQ
TVNKGMMRPALFANLFGVLALFQSGRLVKDQEALMKSVKLLKILSHHYNHLQGQPIKVLV
DILSQVPESMFQEILPKILKGGDLNVILSSPKYLELFLLAQQRVP-----AKLESLMGSV
DLFSEENIPSLVNVLKTAANSVRKEHKLPEVALDLLRLALKENKFTLFWK-EVLEQRLLN
KPCWSASYMCFRLLGASLPLLSEEQLRLVMRGDLIRHFGEHMVISKPQNLFKIIPEISSY
VSTFLEGCQDDPKRQFAMMVAFTSITNQGLPVMPTFWRVTRLLS--SEAL----------
--QSYVTWLRDMFLQPDLDSLVDFSTANQKRAQDASF-----NVPERSVFRLRKWIIHRL
VSL-VEHLHLEKDDAVVEQVARFCFFHAFFKTKKATPQIPETKQHFSFPLDDRNRSVIIG
AFFSLLQTLSMK-------------SRQTPDLNECAKPWTYRLVQLADMLLNHSR-NVTV
VTPF-TTQQRQAWDQMMSTLKELEARSSET-R--ALAFQHLLLLVGLHLFKS------PT
ESCDVLGDIQTCIKKSMEQNPR-RSRS---RAKASQEPAWVEVMVEILLSLLAQPSNLMR
KVVRNVFGHICSHLTPRGLQLILAVLNPETNEDED-DNVVVTDDTNEKQLKRG-----ED
EDSD-----SEDNKNSDSDVDS-EDGAESEEEDRDKD-VDPGFRQQLMEVLQAGNALGGV
DSED----EEELGDEAMMALDQNLASLFAEQKLRIQARQEEKNKLQKEKQLRR-DFQIRV
LDLIEVLVTKQPEHPLILELLEPLLSIIQRSMRSKG---STKQE---QDLLHKTARIFMH
HLCRARHYCHEVGPCAEGLHAQVERLVQQAGSQADASVALYYFNASLYLLRVLKGNTAKR
YE-DGQNLPGA----E---------------------------------------PKDSE
A---------------Q-TANCLDLDFVTRVYSAALESFLTKRNSPLTVPMFLSLFSRY-
------------------------------PVICKNLLPVLV-------QHVSGPLRPRH
QAQACLLLQKTLSARELRVC----FEDPEWEQLIGQVLGKLTQT----------------
--------------------------LQTLGDAQSKGEQQREFSTLELLNILF---KTVN
HEKLSVDLTSVLGLLQSKQQ---KLQQSLQQGNHS--SGSNRLYDL-----YWQAMRMLG
VQ-----------------------RPKSEKKNVKD-VPSDSQSPISQKRKKKGFLPETK
KRKKVKSEDTTPGKDATSGQEVVTAGATPAAAGEGQPPST--GKKKRKR--VKANTPSQV
NGTPV-------------------------------------------------------
------------------------------------TKSPAPNNP---------------
----------------------------------------------------TLSPSTP-
FKSPKLQKKKEKLSQVNGGTPVS---PIEPEGKEHHQKALPTKEVLRKS---PQSALPRK
RAR--LSLVSRSPSLLQSVVKKRKVARRKMQTP------

---------------------------------------------------------MGS
RELAERMSPGEATQSGARPADRHGLLKHSREFLDFFWDIAKPEQETRLAATEKLLEYLRG
RPKGS-EMKYALKRLITGLGVARETARPCYSLALAQLLQSFEDLPLCSILQQIQEKYDLH
QVKKTMLRPALFANLFGVLALFQSGRLVKDQEALMKSVKLLQALAQYQNHLQEQPRKALV
DILSEVSVATLQEILPEVLK-ADLNTILSSPEQLELFLLAQQKVP-----SKLKKLVGSV
NLFSNENVPRLVNVLKMAASSVKKDRKLPAIALDLLRLALKEDKFPQFWK-EVVEQGLLK
MQFWPASYLCFRLLGAALPLLTKEQLQLVLRGDVIRHYGEHVCTAKLPKQFKFAPEMEDY
VGTFLEGCQDDPERQLAVLAAFSSVTNQGLPVAPTFWRVVRFLS--PLAL----------
--QGYVAWLRDMFLQPDLDSLVDFSTNNQKKAQDASL-----HVPERAVSRLRKWIIFRL
VSI-VDSLHLEMEEALTAQVARFCLFHAFFVTKKPTSQIPETKQPFSFPLESQAREAASS
AFFSLLQTLSTQ-------------LKQAPDQTRGGQPWTYHLVQFADLLLNHSH-NVTT
VTPF-SAQQRQAWDRMLQTLKELEAHSSEA-R--AAAFQHLLLLVGIHLLKS------PA
ESCDLLGDIQTCIRKSLGEKPR-RSRT---KAIDPQEPPWVEVLVEILLALLTQPSHLMR
QMARSVFGHICSHLTPRALQLILDVLNPETSEDE--DHVVVTDDSDERRLKGA-----ES
ERCVTCLTAKEQQKAREDEEEMR--GGGSEEEERDGDCLDQGFREQLMSV--AGKALGGE
DSEDE----EELGDEAMMALDQSLASLFAEQKLRVQARRDEKNKLQKEKALRR-DFQIRV
LDLVEVLVTKQPENALVLELLEPLLSIIRRSLRSS----SSKQE---QDLLHKTARIFTH
HLCRARRYCHDLGERAEALHAQVERLVQQAGRQPDSPTALYHFNASLYLLRVLKGNTAEG
CVRETREKQKAGTDP---------------------------------------------
----------STMPTGPQAASCLDLNLVTRVYSSALSSFLTKRNSPLTVPMFLSLFSRH-
------------------------------PLLCKSLLPILV-------QHVTGPVRPRH
Q--ACLLLQKTLSMREVRSC----FEDPEWKQLMGQVLAKVTEN----------------
--------------------------LRVLGEAQTKAEHQQALSSLELLNVLF---RTCK
QEKLTLDLTVLLGVLQGQQQ-------SLQQGAHS--TGSSRLHDL-----YWQAMKTLG
VQR-----------------------PKLEKKGAKE-VPSATQSPISKKRKKKGFLPETK
KRKKRKSEDGTLAE-----------DGTPAATGGSQP--PSMGRKKRKRT--KA------
------------------------------------------------------------
----------------------KVPAQ--ANGTPA-AKSPAPGTP---------------
----------------------------------------------------TLSPSTP-
AKSPELQKKNQKPSQVNGH-P---------------QKALPKKGVLGKSPR---SALARK
KAR--LSLVIRSPSLLQSGAKKKKAQ-LRK--AWKS---

---------------------------------------------------------MGS
REPTQPLSPGDATQNSARPADRHGLLKHSREFLDFFWDIAKPEQETRLAATEKLLEYLRA
RPKGS-EMKYALKRLITGLGVGRETARPCYSLALAQLLQSFEDLPLCSILQQIQEKYDLH
QVKKSMVRPALFANLFGVLALFQSGRLVKDQETLRKSVKLLQALAQYQNHLQEQPRKALV
DILSEVSEATLREMLPEILS-TDLDVMLSCPEQLGLFLLAQQKVP-----SRLKKLVGSV
NLFSDENVPRLVNVLKMAASSVKKERRLPAVALELLRLALKEDKFLRFWK-GVVEQGLLK
LQFWPASYLCFRLLGAALPLLTKEQLQLVMRGDVIRHYGEHTCTAKLPNQFKFAPEMEEY
VGTFLEGCRDDPERQLAVLVAFSSTTNHGLPVVPTFWRVVRFLS--PQAL----------
--QGYVAWLQGMFLQPDLDSLIDFSTNNQKKAQDAWL-----HVPERAVFRLRKWIILRL
VSL-VDSLHLEMEESLMEQVARFCLFHSFFVTKKPTSQIPETRQQLSLPLESQAREAVSS
AFFSLLQTLSTQ-------------FKPASEQTGGGPPWTYRLVHFADLLLNHSH-SVTP
VTPL-TAQQRQAWDRMLQTLKELEAPSSEP-R--AAAFQHLLLLVGIHLFKS------PT
ESCDLLGDIQTCIRKSLGERRR-GSRT---KAIDPQEPPWVEVLVEILLALLAQPSHLMR
QVARSVFGHVCSHLTPRALQLILDVLNPETSEDED-DHVVVTDESDERWLKAA-----ED
KSED-----SEENRGSESEDESD--GGESEEEERDGD-VDQGFREQLMSVLQAGKALGGE
ESEDE----EELGDEAMMALDQSLASLFAEQKLRIQARRDEKSRLQKEKALRR-DFQIRV
LDLVEVLVTKQPENVL--------------------------QE---KDLLPKTARLCAH
HLCRGRRYCHDLGDRVEALHGQVARLVEQAGRQPDSSTALYHFNASLYLLRVLKGSTAEG
RVHETQEELEAGTDPS---------------------------------------PAPEG
P----------------QAAGCLDLNLAMHVYSSALSSFLTKRHSPLTVPMFLSLFSRH-
------------------------------PVLCKSLLPVLI-------QHITGPGRPRQ
Q--ACLLLQKTLSMREVRSC----FQDPEWKQLIGQVLTKVTEN----------------
--------------------------LRALGEAQTKAEHQQALSSLELLNTLF---RTCK
HEKLTLDLTVLLGVLQGQQQ-------GLQQGAHS--TGSSRLLDL-----YWQAMKTLG
VQR-----------------------PKLEKKDAKE-IPSATQSPISRKRKKKGFLPETK
KRKKHTSE-----------------DGTPAATGGSQP--PGTGRK-RNRT--KA------
------------------------------------------------------------
----------------------KVPAR--ANGMPT-TKSPAPGTP---------------
----------------------------------------------------TLSPSTP-
AKSPKLRKNNQKLSQMNGA-PGS---PTKPAGQKHHHEALPKKGVLDKLPP---STLARK
KAR--PPLVIRSPSLLQSGSKKK-KAQLRK--AGNSSKK

------------------------------------------------------MAEVKG
FAKAEPEASGEAP-----HADRHGLLEHSREFLDFFWDIAKPQQETRLEATEKLLEYLRT
RPT-GSEMKYALKRLITGLGVGREAARPCYSLALAQLLQSFENISLCSILKQIEEKYDLQ
KVKKAMMRPALFANLFGVLALFQSGRLVKDQEALMKSVKLLKILTHHYNHLQGQPLKAIV
DILSEVPETMFEEILPKVLT-GDLKVVLSSPKHLELFLLAQRRVP-----AKLESLMGSV
DLFSDENIPSLVNVLKMAATSVKKEHRLPDVALDLLRLALKEDKFPLFWK-EVVEQGMLK
KPCWASSYLCFRLLGASLPLLSEDQLRLVMRGDLIRHFGEHVVVAKPQNLFKFIPEMSKY
VGTFLEGCRDDPERQFAMLVAFSSITNQGLPVMPTFWRVTRFLN--AEAL----------
--QRYVSWLRDMFLQPDLDSLVDFSTTNQKKAQDASF-----NVPERAAFRLRKWIVHRL
VSL-VDHLHLEMDEALVEQVARFCLFHAFFKTKKATPQIPETKQLFSFPLDNRTREVIIS
TFFSLLQTLSAK-------------FRQTD-QAKGWRPWTYRLVQFADILLNHNR-NVAI
VTPF-TKQQRQAWDEMLKTLKELEACSSET-K--ATAFQHLLLLVGLHLFKS------PT
ESCDLLGDIQTCIKKSMEQKPR-RSRS---KANTSQEPPWVEVMVEILLSLLAQPSHLIR
QVARNVFGHICSHLTPHALQLILAVLNPETND-ED-ENVVVTDDSSEKQLKHA-----ED
EGSD-----SEDSKNSVSDMDS-EDEEESEEEDRDED-VDPGFRQQLMAVLQSGKALGGE
DSED----EEELGDEAMMALDENLASLFAEQKLRIQAQREEKNKLRKEKTLRR-DFQIRV
LDLIEVLVTKQPENPLVLELLEPLLSIIQRSMRSSS---STKQE---QDLLHKTARIFMQ
HLCRARHYCHKVEPCTDALHTQVERLVQQAGTQANASVALYYFNASLYLLRVLKGNTSKK
YQ-DSQKPQGAGTKPE---------------------------------------PVDSE
A---------------Q-AANCLDLNFVTRVYSAALESFLTKRNSPLTIPMFLGLFSRY-
------------------------------PMICKSLLPVLV-------PYVASPSRPRH
QAQACLLLQKTLSAKELRVC----FEDPEWEQLIGQVLDKVTQI----------------
--------------------------LHNLGEAQSKAEHQKELSSLELLNTLF---KTVN
HEKLTVDLTALLGVLQGQQQ---KLQQNLQQGNHS--SGSSRLHDL-----YWQAMKMLG
VQ-----------------------RPRSEKKDAKD-APNVTQSPISTKQKKKGFLPETK
KRKRK-SK------DVTPEQDVMPENATLAVTGGDQPPST--GKKRRRK--MKAQAQAQV
NGTPA-------------------------------------------------------
------------------------------------TKSLASNNL---------------
----------------------------------------------------TLSPTTP-
AETPKLQKKKEKLSQVNGTTPVS---PIEPEGKKQHQKALPIKEVLNKS---PKSALPRK
KAR--LSLVSRSPSLLQSGARKRKVVRKKEQTP------

------------------------------------------------------MAEMES
QEMSAPVSPGEATQSGALPADRHALLQHSREFLDFFWDIAKPQQKTRLEATEKLLEYLRT
RPQGS-EMKYALKRLITGLGVGRETARPCYSLALAQLLQSFEDIPLCSVLQQIQEKYDLH
HVKKATVRPVLFGNLFGVLALFQSGRLVKDQEALMKSVKLLQALAQHYNHLQEQPQKALV
DIMSEVPEAMLQEILPKVLK-ADLNVILNSPERLELFLLAQQKVP-----TKLKSMMGSV
NLFSDENVPRLVNVLKMASSSVKKERKLPPVARDLLHLALKEDKFPRFWK-EVVEQGVLK
KQSWPASYLCFRLLGEALPLLSKEQLQMVMRGDLIRHYGEHMVTAKLPNQFRFAPEMDNY
VGTFLEGCQDDPERQLAVLVAFSSITNQGLPVVPSFWWVVRFLS--PPAL----------
--QGYVAWLQDMFLHPNLDSLVDFSTNNQKKTQDASL-----HVPERAVARLRKWLIHRL
VSI-VDNVHLEKEEALVEQVARFCLFHSYFVTKKPMSQIPETKQQFSFPLESQSREVVSN
AFFSLLQTLTTQ-------------FKQAPDQTQGGQSWTYRLVQLADKLLSHSR-SVTT
VMPF-TTQQRQAWDQMLQTLKELEAHSTEA-R--AAAFQHLLLLVGIHLFKS------PA
ESCDLLSDIQTCIKKSLGEKTR-RSRA---KATNSQELPWVEVLVEILLALLAQPSHLMR
QVARSVFGHICSHLTPRALQLILDVLNPEMSQDED-EHVVVTDDSDKKQLEDT-----ED
KSED-----SEDNKNSESEEESE-DEEESEEEDREGD-VDQGFREQLMAVLQAGKALGGA
DSEDE---EEELGDEAMMALDQSLASLFAEQKLRIQARRDEKNKLQKEKALRR-DFQIRV
LDLIEVLVTKQPENPLVLELLQPLLSIIRHGMRSGG---SSQQE---RDLLHKTARIFTH
HLCRARRYCRDLGDRVETLHTQIEQLVQQASRQADSSVALYHFNASLYLLRVLKGNAAES
CSLKTQKQPGASTNTS---------------------------------------LTPKD
PE----------------TTSCLDLNLVTPVYSTALSSFLTKRNSPFTVPMFLSLFSRQ-
------------------------------PVLSKNLLPILV-------QHIAGPTRPRH
QAQACLLLQKTLSMRELRLC----FEDPEWKQLIGQVLAKVTEN----------------
--------------------------LRALGVTQTKAEHQKELCSLELLNALF---RTIH
HEKLTLDLTMLLGVLQGQQQ---SLQQSLQQGEHS--TGSSRLHDL-----YWQAMKALG
VQ-R----------------------PKMEK-ETKE-VPSTIQDPVSLKRKKKGFLPETK
KRKKRKPEDVTPEE-----------DAKPAATGGGQSPSTGKKKKRRKRT--KD------
------------------------------------------------------------
----------------------KVPVQSQVNGTPA-VKSPASDTS---------------
----------------------------------------------------ALSPSTP-
AKTPELQKKHQKPSQVNGATPMS---PTEPAVKKQHQKALPQKGMSGKSPQ---SPLPRK
RAR--LTLASRGPSLFQSGAKKKKVQLKKVRR--P----

-------MAGTRSSRSTRGSRAAAAA--AAVEAV--------------LEPAESVEVAEE
TT--ETAMAVEAAGTEEPESGPGPLLQQSRDFLDLFWGIAKPAQEERLAATAALVGRLRE
RPQEA-ELQYALKRLIEGLGATREAARPGFSLALSQVLQALDHVPLRRVWEQVKEKHDLQ
--KKKLLRSAAFGNFFGVLALFQSGRLVKDPKVLVEAVQLLQSLAQHRNHLQDLPRRTLV
DILSEIPEPVFEEVLLGVLQ-DDFASAFSTPEQLQLLLVGLQKFPGVLQPKKLKKLLGSP
AVVTKETVPRLVEVLNVAAKSVKKEKVLPPVALELLRVALQEGAFELFWK-EVVEKGLLQ
EHSGPGSYTAFRLLGTALPLLNLEQLRVLLRGEVMRRYGDHVLSAQLPSRFKFAPEMEKY
VDSFLEGC-ADPEKQLAVLVAFSSLTNQGYPVVPSVWPVTLCQRLVPVVLPFVTAGVRPY
HQAQACVMLLKALQLRELKQALGAP----------GWQELIGDAIE------R-VT----
ESLKASSQ-AGNKSGHLRTFKALE-LLLFLLRTVKDEKLPVG----------------LE
APLAVLQELRQSRALGATGRLSD-------------LTWQALK------LLGVQRPKEDK
VRPPKNKEDAAAPE----------------------------------------------
------GPGSRKRKKGFLPETKKRRKRRQEEGPA-EAPGGGQEPPSAEGSLGG-----KR
RRKRRKRPKQHPALPGPGVNGTPKSPQP------PSGPPGLDSSQGEAPASPG-----PK
RKHQ--AGKRKDS--PDAAP--------------------LVKRAKLPTAVGKGSP----
--------KTQLRK----------------KQ------KPGSEGAASERA--GPGCHTGI
LRTRDLFLPPIQ------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------MAEIRS
PKVAEPAPPGGAM-----SADRHGLLEHSREFLDFFWDIAKPHQQTRLEATEKLLAYLRA
RPE-GSERKYALKRLITGLGVGREAARPCYSMALAQLLQSFEDIPLCSILEQVQEKYDLN
TAKKATIRPVLFANLFGVLALFQSGRLMKDQKALMKSVKLLQVLSHHYNHLQGQPLQALV
DILSEVPEAMFEELLPKILR-ADFSVILSSPRHLELFLLAYRKVP-----SKLKSWMGSI
DLFTDENMPRLVNVLRLAATSAKKENKLPNVALDLLRLALKENKFPSFWK-EVLEQGLLT
KASWPASFLCFRLLGAALPLLSKEQLQLVMRGDLARHFGEHMVTAKLSSQSKFIPEMSEY
VGTFLEGCQDDPARQLSVMVAFSSITNQGLPVMPTFWRVTKFLS--SQAL----------
--RDYMAWLQDMFLRPNLDCLVDFSTANQKREQDASF-----NSPERAVFRLRKWIIHRL
VSL-LDTLQLEKEETLVEQVARFCLFHSFFKTKKPTGQIPETKQQFSLDMDSRIREFFVN
AFFSLLQTLTTK-------------SRHVPGQAHSGHPWIYRLVQLADMLLNHSR-NVAI
ITPF-TTQQRQAWDHMLETLKELEARSSEP-K--AAAFQHLLLLVGLHLFKS------PT
ESCDLLGDIQTCIKKSMGEKTR-RSRS---KAINAKEPPWVEVMVEILLSLLSQPSNLMR
QVARSVFGHICSHLTPRALQLILNVLNPEANQDED-DAVVVTDDSDEKQLMDA-----ED
ESSD-----SKDE-NSESEA-D-SEGEESEEEERDEH-VDPGFRQQLMEVLQAGKALGGE
DSEE-----EELSDEAMMALDESLSSLFAEQKLRIQAQRDEKNKLQKEKTLRR-DFQIRV
LDLVEVLVTRQPESPLVLELLEPLLNIIQRSMRSGG---SSKQE---QDLLHKTARIFMH
HLCRSRHYCRDVGHCTSALHGQVERLVRQAGQQADSSVTLYYFNASLYLLRVLKGSANKK
HVPGGQQQQGTGASDV---------------------------------------PEDSD
S---------------Q-TTNCLDLDLVAPVYSAALSSFLTKRNSPFTVPMFLSLFSRY-
------------------------------PTICKRLLPVLL-------QCLAGSSRARQ
QTQACLLLQKTLSARELRVC----FEDPEWEPLIGQVLAKVTEN----------------
--------------------------LRELGEAQSKSENQKQLTSLELLNTLL---RIIH
HEELAVDLTALLGVLQGQQQ---RLRQSLQQGEHS--IGSSRLYDL-----YWQAMKMLG
VQ-----------------------RPKVEKKDTKE-VPGTSESPISTKRKKKGFLPETK
KRKKRKLEAAAPEEGAK------PEGATPVATGGNQPPST--GKKKRRRAKAKGLAQPQV
NGTPA-------------------------------------------------------
------------------------------------TKSPAPGAP---------------
----------------------------------------------------ALSPSTP-
AKTPELKKKSKRLSRVNGDTPVS---PTEPSGKEQHQKVLAKKGISGKS---PQSTLPRK
RSR--LSVV-RSPSLFQSGAKKKKSLRKKLRTP------

------------------------------------------------------MAEMKS
PTKAEPATPAEAA-----QSDRHSLLEHSREFLDFFWDIAKPDQETRLRATEKLLEYLRT
RPN-DSEMKYALKRLITGLGVGREAARPCYSLALAQLLQSFEDIPLCDILDQIQEKYSLQ
AMNKAMMRPSLFANLFGVLALFQSGRLVKDKEALMKSVQLLKILSQHPNHLQGQPIKALV
DILSEVPESMFQEILPKVLK-GNMKVILRSPKYLELFLLAKQRVP-----TKLESLMGSV
DLFSEDNIPSLVNILKVAANSVKKEHKLPNVALDLLRLALKESRFELFWK-KVLEEGLLK
NPSWTSSYMCFRLLGASLPLLSEEQLQLVMRGDLIRHFGENMVISKPQNLFKIIPEISTY
VGTFLEGCQDDPKRQLTMMVAFTTITNQGLPVMPTFWRVTRFLN--AEAL----------
--QSYVAWLRDMFLQPDLNSLVDFSTANQKRAQDASL-----NVPERAVFRLRKWIIHRL
VSL-VDHLHLEKDEAVVEQIARFCLFHAFFKTKKATPQIPETKQHFSFPLDDRNRGVFVS
AFFSLLQTLSVK-------------FRQTPDLAENGKPWTYRLVQLADMLLNHNR-NVTS
VTSL-TTQQRQAWDQMMSTLKELEARSSET-R--AIAFQHLLLLVGLHIFKS------PA
ESCDVLGDIQTCIKKSMEQNPR-RSRS---RAKASQEPVWVEVMVEILLSLLAQPSNLMR
QVVRSVFGHICPHLTPRCLQLILAVLSPVTNEDED-DNVVVTDDADEKQLQHG-----ED
EDSD-----NEDNKNSESDMDS-EDGEESEEEDRDKD-VDPGFRQQLMEVLKAGNALGGV
DNEE----EEELGDEAMMALDQNLASLFKEQKMRIQARNEEKNKLQKEKKLRR-DFQIRA
LDLIEVLVTKQPEHPLILELLEPLLNVIQHSMRSKG---STKQE---QDLLHKTARIFMH
HLCRARRYCHEVGPCAEALHAQVERLVQQAGSQADASVALYYFNASLYLLRVLKGNTNKR
HQ-DGHKLHGADT-------------------------------------------EDSE
D---------------Q-AANCLDLDFVTRVYSASLESLLTKRNSSLTVPMFLSLFSRY-
------------------------------PVICKNLLPVLA-------QHVAGPSRPRH
QAQACLMLQKTLSARELRVC----FEDPEWEQLITQLLGKATQT----------------
--------------------------LQTLGEAQSKGEHQKELSILELLNTLL---RTVN
HEKLSVDLTAPLGVLQSKQQ---KLQQSLQQGNHS--SGSNRLYDL-----YWQAMRMLG
VQ-----------------------RPKSEKKNAKD-IPSDTQSPVSTKRKKKGFLPETK
KRKKLKSEGTTPEKNAASQQDAVTEGAMPAATGKDQPPST--GKKKRKR--VKASTPSQV
NGITG-------------------------------------------------------
------------------------------------AKSPAPSNP---------------
----------------------------------------------------TLSPSTP-
AKTPKLQKKKEKLSQVNGATPVS---PIEPESKKHHQEALSTKEVIRKSPH-PQSALPKK
RAR--LSLVSRSPSLLQSGVKKRRVASRRVQTP------

---------------------------------------------------------MES
QDGAEPMSPGEATPNGARPADRHDLLKHSREFLDFFWDIAKPQQETRLEATEKLLEYLRT
RPEGS-EMKYALKRLITGLGVGRETARPCYSLALAQXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXIPEAMLQEVLPKVLK-ADLNVVLSSPEHLELFLLAQQKVP-----TKLENLMGPV
DLFSAENIPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNLIRHYGEHW-TAKVPNQFKFAPEMHEY
VDTFLEGCREDPERQLALLVAFSSVTNQGLPVMPTFWRVVRFLS--PRAQ----------
--QDYVAWLQDMFLRPDLDSLVDFSTPNQKKTQDASL-----HVPERAVFRLRKWIILRL
VSI-VDTLQLETEESLVEQVARFCLFHSFFETKKPTVQIPETKQQLSFPLESRTREVVSS
AFFSLLQTLSTQ-------------PWLTQARTQGKQPWASRLVQLADQLLNHSR-NVAT
VAPF-TTKQRQAWDRMLQTLKELEAHSSEA-K--ATAFQHLLLLVGIHLFRS------PA
ESCDLLGDIQTCIKKSLAEKTR-RTRS---KATSSQEPPWVEVLVEILLALLAQPSNLMR
QVARSVFGHICSHLTPRALQLILDVLNPEASEDED-DNVVVTDDADEQQLKDT-----ED
KSSD-----SEEDKNSES-----EEEEESEEEDRDKD-VDQGFREQLMAVLQAGKALGGA
DSEDD---EEELGDEAMMALDQNLASLFAEQKLRIQAEDEKXXXXXXXXXXXX-XXXXXX
XXXXXXXXXXXXXXXXXXX-----XXXXXXXXXXXX---XXXXXXXXXXXXXXXXXXXXH
QLCRARRYCQDVGDYVETLHAQVQRLVQQAGRQAESAVALYYFNASLYLLRVLRGNTEKG
ARQKQRESTNTS-------------------------------------------SQPK-
---------------GAQAASCLDLNLVAPVYSAALSSFLTKRNSPLSVPMFLSLFSRH-
------------------------------PVLCKSLLPVLV-------QHMAGPTRPRQ
Q--ACLLLQKTLTMREVRAC----FEDPEWERLIGQVLTKVTEN----------------
--------------------------LRTLGEAQSKSEQQKELFSLELLNSLF---KTIN
HEKLTVDLTALLAMLQGRQQ-------SLQQGERP--AGTSRLCDL-----YWQAMKYLG
V-----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------MAETES
MDVAEPVSPVEVPKTGAGPADRHGLLKHSREFLDFFWDIAKPQQETRLEATEKLLEYLRA
RPKGSSEMKYALKRLITGLGVGRETARPCYSLALAQLLQSFEDIPLCSILQQIQEKYNLQ
KVKKGMMRPALFANLFGVLALFQSGRLVKDSEVLMKSVKLLQVLAQHYNHLQEQPQKALV
DILSEVPEAVLQEVLPKVLK-TELSSVLGSPEHLELFLLAQQKVP-----KKLEKLMGPV
NLFSDENIPRLVTVLKMAATSVKKERKLPAVALDLLRLALQEDKFPWFWK-EVVEQGLLK
KQFWPASYLCFRLLGAALPLLSKEQLQLVMRGDLIRHYGEHMVTAKLPNHYKFAPEMNQY
VEAFLEGCRDDAERQLAMVVAFTSVTNQGLPVMPTFWRVVKLLS--PPAL----------
--QGYVAWLRDMFLQPDLDALVDFSTNNQKKTQDASL-----HGPERAVFRLRKWIILRL
VSI-VDCVHAEKEEALTEEVARFCFFHSFFETKKPTSQIPETEQHFSPALESRTREVVSG
AFFSLLQTLSTQ-------------FRQAPEQAQDRQPWTYRLVQFADMLLSHSR-NVVP
LTPF-TTQQRQAWDRMLKTLKELETHSSEA-KAKATAFQHLLLLVGIHLFKS------PA
ESCDLLGDIQTCIKKSLGEKTR-RTRS---KATNPQELPWVEVLVEILLSLLAQPSHLMR
QVARSVFSHICSHLTPRALQLILDVLNPEESQDED-DNVVVTDDSKEEPLGEA-----ED
KSSDDEDNKGDKN--SES--EEESDGEESDEAERDGD-VDQGFREQLMAVLQAGKALGGG
DGEDD--DDEELGDEAMMALDENLASLFAEQKLRIQARREEKNKLQKEKALRR-DFQIRV
LDLIEVLVTKQPENPLVLELLEPLLHIIRRSMRT-S---SAKQE---QDLLHKTARIFTH
HLCRSRHYCRDVGDRVETVYAQLERLVRQAGQQADSSVALYHFNASLYLLRVLKGSTVDK
SAQKEKTTAADASAQGREVSRPDPGRLPCPEMGARPRGRGATRPFHGVGVEAKPSPGSSG
PPSEGSPASHCALSLVVQAATCLDLSRVTPIYSAVLSSFLTKRNSPLTVPMFLSLFCRH-
------------------------------PMLCKNLLPLVV-------EHIASHSRPRH
QAQACLLLQKSLHTRELRLC----FKAPEWEQLMGQILAKVSEN----------------
--------------------------LRTLGEAETKSEHQKELSSLELLNTLF---KNIR
QEKLTTDLSAVLGVLQSQQP---RLQQKLQQEEHSTGTGSSRLHDL-----YWQAMKLLG
VQR-----------------------PKSEKDAKEV-PEAT-QNPVSMKRKKKGFLPETK
KRKKRKSEGAVQGE-----------GAAPAATGGDQPPST--GKKRRNKRKAKVPAPSQV
NGMPAAKSPAPDSPAQPPKPKKRKRKQSQVNGTPATKSPAPDSPAQTPKPQKQNEKQSQV
NATPAIESPAPDLSAQTPKPQKKNPKLSQVNGTPA-TRSPAPDPPTQTPKLQKKNQKLSQ
ANAMPATKSPAPGPPAASPTASAQTPKLQKKNQKLSQVTVTPATKSPVSDLPTISPGPP-
AQTPKLQKKNQKLSQMKGATPESLDSPEEPAAKKRPKKNLPQKGILGKSPQ---SALPRK
KAR--LSLASRSPSLLQSGARKKVQP-RKVKK--L----

------------------------------------------------------------
------------------------------------------------------------
------------------------------------LLQSFEDIPLCSILEQVQEKYDLN
TAKKATIRPVLFANLFGVLALFQSGRLMKDQKALMKSVKLLQVLSHHYNHLQGQPLQALV
DILSEVPEAMFEELLPKILR-ADFSVILSSPRHLELFLLAYRKVP-----SKLKSWMGSI
DLFTDENMPRLVNVLRLAATLAKKENKLPNVALDLLRLALKENKFPSFWK-EVLEQGLLT
KPSWPASFLCFRLLGAALPLLSKEQLQLVMRGDLARHFGEHMVTAKLSSQSKFIPEMSEY
VGTFLEGCQDDPARQLSVMVAFSSITNQGLPVMPTFWRVTKFLS--SQAL----------
--RDYMAWLQDMFLRPNLDCLVDFSTANQKREQDASF-----NSPERAVFRLRKWIIHRL
VSL-LDTLQLEKEETLVEQVARFCLFHSFFKTKKPTGQIPETKQQFSLDMDSRIREFFVN
AFFSLLQTLTTK-------------SRHVPGQAHSGHPWIYRLVQLADMLLNHSR-NVAI
ITPF-TTQQRQAWDHMLETLKELEARSSEP-K--AAAFQHLLLLVGLHLFKS------PT
ESCDLLGDIQTCIKKSMGEKTR-RSRS---KAINAKEPPWVEVMVEILLSLLSQPSNLMR
QVARSVFGHICSHLTPRALQLILNVLNPEANQDED-DAVVVTDDSDEKQLMDA-----ED
ESSD-----SKDE-NSESEA-D-SEGEESEEEERDEH-VDPGFRQQLMEVLQAGKALGGE
DSEE-----EELSDEAMMALDESLSSLFAEQKLRIQAQRDEKNKLQKEKTLRR-DFQIRV
LDLVEVLVTRQPESPLVLELLEPLLNIIQRSMRSGG---SSKQE---QDLLHKTARIFMH
HLCRSRHYCRDVGHCTSALHGQVERLVRQAGQQADSSVTLYYFNASLYLLRVLKGSANKK
HVPGGQQQQGTGASDV---------------------------------------PEDSD
S---------------QATTNCLDLDLVAPVYSAALSSFLTKRNSPFTVPMFLSLFSRY-
------------------------------PTICKRLLPVLL-------QCLAGSSRARQ
QTQACLLLQKTLSARELRVC----FEDPEWEPLIGQVLAKVTEN----------------
--------------------------LRELGEAQSKSENQKQLTSLELLNTLL---RIIH
HEELAVDLTALLGVLQGQQQ---RLRQSLQQGEHS--IGSSRLYDL-----YWQAMKMLG
VQ-----------------------RPKVEKKDTKE-VPGTSESPISTKRKKKGFLPETK
KRKKRKLEAAAPEEGAK------PEGATPVATGGNQPPST--GKKKRRRAKAKGLAQPQV
NGTPA-------------------------------------------------------
------------------------------------TKSPAPGAP---------------
----------------------------------------------------ALSPSTP-
AKTPELKKKSKRLSRVNGDTPVS---PTEPSGKEQHQKVLAKKGISGKS---PQSALPRK
RSR--LSVV-RSPSLFQSGAKKKKSLRKKLRTP------

---------------------------------------------------------MGS
RELAEPLSPGEATQSGARPADRHGLLKHSREFLDFFWDIAKPEQETRLAATEKLLEYLRG
RPKGS-EMKYALKRLITGLGVARETARPCYSLALAQLLQSFEDLPLCSILQQIQEKYDLC
EVKKTMLRPALFANLFGVLALFQSGRLVKDQEALMKSVKLLQALAQYQNHLQEQPRKALV
DVLSEVSVATLQEILPEVLK-ADLNTILSSPEQLELFLLAQQKVP-----SKLKKLVGSV
NLFSDENVPRLVNVLKMAAASVKKDHKLPAIALDLLRLALKEDKFPRFWK-EVVEQGLLK
MQFWPASYLCFRLLGAALPLLTKEQLQLVLRGDVIRHYGEHVCTAKLPKQFKFAPEMEDY
VGTFLEGCQDDPERQLAVLVAFSSVTNQGLPVVPTFWRVVRFLS--PPAL----------
--RGYVAWLRDMFLQPDLDSLVDFSTNNQKKAQDASL-----HVPERAVFRLRKWIIFRL
VSI-VDSLHLEMEEALTAQVARFCLFHAFFVTKKPTSQIPETKQPFSFPLESQAREAASS
AFFSLLQTLNTQ-------------LKQATEQTRGGQPWTYHLVQFADLLLNHSH-NVTT
VTPF-SAQQRQAWDRMLQTLKELEAHSSEA-R--AAAFQHLLLLVGIHLLKS------PA
ESCDLLGDIQTCIRKSLGEKPR-RSRT---KAIDPQEPPWVEVLVEILLALLAQPSHLMR
QVARSVFGHICSQLTPRALQLILDVLNPETSEDE--DHVVKVCRRGR-------------
-------------------------------------------------------VGGGG
V-----------------------------------------------GTPVR-RCVLRV
LDLVEVLVTKQPENALVLELLEPLLSIIRRSLRSS----SSKQE---QDFLHKTARIFTH
HLCRARRYCHDLGERAEALHAQLERLVQQAGRQPDSATALYHFNASLYLLRVLKGSTAEG
CGRETREKQKAGTDPS---------------------------------------P----
----GPTLSLLK---GGQAASCLDLNLVTRVYSSALSSFLTKRNSPLTVPMFLSLFSRH-
------------------------------PVLCKRLLPILV-------QHVTGPVRPRH
Q--ACLLLQKALSLREVRSC----FEDPEWKQLMGQVLAKVTEN----------------
--------------------------LRVLGEAQTKTEHQQALSSLELLNALF---RTCK
QEKLTLDLTVLLGVLQGQQQ-------SLQQGAHS--TGSSRLHDL-----YWQAMKTLG
VQR-----------------------PKLEKKGAKE-APSATQSPISKKRKKKGFLPETK
KRKKRKSEDGTLAE---------DEDGTPAATGRSQP--PSMGRKKRNRT--KA------
------------------------------------------------------------
----------------------KVPAQ--ANGTPA-TKSLAPGTP---------------
----------------------------------------------------TLSPSSA-
AKSPKLQKKSQKPSPVNGA-PRS---PVEPAGQKQHQKALPEKGVLGKSPL---SAPARR
KAR--LSLVSRSPGLLQSGAKKKK--TLRF--TISSPKK

------------------------------------------------------MAEMKS
PTKAEPATPAEAA-----QGDRHSLLEHSREFLDFFWDIAKPDQETRLRATEKLLEYLRT
RPS-DSEMKYALKRLITGLGVGREAARPCYSLALAQLLQSFEDIPLCDILDQIQEKYNLQ
AMNKALMRPILFANLFGVLALFQSGRLVKDKEALMKSVQLLKTLSQHHNHLQVQPVKALV
DILSEVPESMFQEILPKVLK-GNMKVILRSPKYLELFLLAKQRVP-----TKLESLMGSV
DLFSEDNIPSLVNILKVAAKSVKKEHKLPNVALDLLRLALKENRFELFWK-KVLEEGLLK
NPSYTSSYMCFRLLGASLPLLSEEQLQLVMRGDLIRHFGENMVTSKPQNLFKIIPEISVY
VDTFLEGCQDDPKRQLTMMVAFTTITNQGLPVMPTFWRVTRYLN--AEAL----------
--QSYVAWLRDMFLQPDLDSLVDFSTTNQKKTQDTSL-----NVPERTVFRLRKWIIHRL
VSL-VDHLHLEKDEAVIEQIARFCLFHAFFKTKKATPQIPETKQHFSFPLDDRNRGVFVS
AFFSLLQTLSVK-------------FRQTPDLAENGKPWTYRLVQLADMLLNHNR-NVTS
VTSL-TTQQRQAWDQMMSTLKELEARSSET-R--AIAFQHLLLLVGLHIFKS------PA
ESCDVLGDIQTCIKKSMEQNPR-RSRS---RAKASQEPVWVEVMVEILLSLLAQPSNLMR
QVVRSVFGHICPHLTPRGLQLILAVLSPVTNEDED-DNVVVT-DTDEKQLQHG-----ED
EDSD-----NEDNKNSESDVDS-EDGEESEEEDRDKD-VDPGFRQQLMEVLKAGNALGGV
DNEE----EEELGDEAMMALDQNLASLFKEQKMRIQARNEEKNKLQKEKKLRR-DFQIRV
LDLIEVLVTKHPEHPLILELLEPMLNMIQHSIRSKG---STKQE---QDLLHKTARIFMH
HLCRARRYCHEVGPRAEALHAQVERFVQQAGSQADASVALYYFNASLYLLRVLKGNTNKR
HQ-DSQKLHGADTGPE---------------------------------------PKDSE
D---------------Q-TANCLDLDFVTRVYSASLESLLTKRNSSLTVPMFLSLFSRY-
------------------------------PVICKNLLPILV-------QHVAGPSRPRH
QAQTCLMLQKTLSARDLRVC----FEDPEWEQLITQLLGKATQT----------------
--------------------------LQTLGEAQSKGEHQRELSILELLNTLL---RTVN
HEKLSVDLTAPLGVLQSKQQ---KLQQSLQQGNHS--SGSNRLYDL-----YWQAMRMLG
VQ-----------------------RPKSEKKNAKD-IPSDTQSPVSTKRKKKGFLPETK
KRKKRKSEGTTPEKNAASQQDAVTEGAMPAATGKDQHPST--GKKKRKR--VKASTPSQV
NGITV-------------------------------------------------------
------------------------------------AKSPAPSNP---------------
----------------------------------------------------TLSPSTP-
AKTPKLQKKKEKLSQVNGATPVS---PIEPESKKHHQEALSTKEVIRKSP---QSALPKK
RAR--LSLVSRSPSLLQSGVKRRRVASRRVQTP------

------------------------------------------------------------
------------------------------------------------------------
-------MKYALKRLVTGLGAGRETARPCYSVALAQLLQSFEDIPLCSVLQQIQEKHDLQ
KAKKAMMRPALFANLFGVLALFQSGRLVKDSEALMKAVKLLQILAQHHNHLQEQPQKALV
DILSEVPEAVLQEILPKVLK-ADLNSVLGSPEHLELFLLAQQKVP-----EKLKELIGPV
NLFSDENIPRLVNVLKTAAASVKKERKLPTVALDLLRLALQEGRFPWFWK-EVVEQGLLK
KQFWPASYLCFRLLGTALPLLSKEQLPLVMQGDLIRHFGEHMVTAKLPNQFKFAPEMNEY
LSAFLESCRDDPERQLAVVVAFTCVTNQGLPVLPTFWRVVRSLS--APAL----------
--KGYVAWLRDMFLRPDLDSLVDFSTSGQKKAQDASL-----HVPERAVLRLRKWVILRL
VSM-VDALHAEKEEDVIEEVARFCFFHSFFETKKPTSQIPETEQRFSFPLESRTREVVSS
AFFSLLQTLSTQ-------------FRQAPEPTQDRPPWTHRLVQFADSLLNRSR-NVTP
LTPF-SSQQRQAWDRMLQTLKELDACPPEA-KAKASAFQHLLFLVGVYLFKS------PV
ESCDLLGDIQTCIKKSLGEKTR-RTRS---KAANPQEPPWVEVLVEILLALLAQPSHLMR
QVARTVFSHICSHLTPRALQLILDVLNPEQSPEED--SVVVTDDSE-KQLESE-----GD
KSSE-----SEDDKHSASEEDSD--EEDSDEEDRDGD-VDQGFREQLMAVLQAGKALGTV
DGEDDD--DDELGDEAMMALDQSLASLFAEQKLRIQARRDEKNKLRKEKVLRR-DFQIRA
LDLIEVLVTKQPENPLVLELLEPLLDIIRRSMRSS----SSKQE---QDLLHKTARIFTH
HLCRSRHYCHDVGRCVGPLYAQVERLVEQAGRQADTTISLYYFNAALYLLRVLKGNATD-
PACKTQKKEKAGP-------------------------------------------KPRA
PE----------------ATGGLDLSLVTPVYSSALTSFLTKRNSPLTIPMFLSLFSRH-
------------------------------PVLCKSLLPVVI-------QHVSGPARPRH
QAQACVLLQKALPTRELRLC----FEDPEWEQLVGQILAKVTEN----------------
--------------------------LRTLGEAQAKSEQQKELSSLGLLNTLF---RTVH
QEREGDGMLRQKGQPG--VH-------EGRGGKHW--AGSSGLHNL-----YCQTMKTLG
AQRR----------------------PKSGKKDAKE-APSAAETPVSTKRKKKGFLPETK
KRKKRKSEGAVPEE-----------DAKPAASAGDQP--PSTGKKRRHKR--KA------
------------------------------------------------------------
----------------------RAPAQAPENGTPAP-KGPAPDPS---------------
----------------------------------------------------TTSPGTP-
AKTPKPQKKKRKLSQVNGATPVS---PVPSSG-KKPQKDVPEKGVSGKSPQ---SALPRK
KAR--LSLASRSPSLLQGTAKRKKA-LRKARKP------

---------------------------------------------------------MGS
RDPAEPMSLGEATQSGVRPADRHGLLKHSREFLDFFWDIAKPEQETRLAATEKLLEYLRG
RPKGS-EMKYALKRLITGLGVGRETARPCYSLALAQLLQSFEDLPLCSILQQIQEKYDLH
QVKKAMLRPALFANLFGVLALFQSGRLVKDQEALMKSVKLLQALAQYQNHLQEQPRKALV
DILSEVSKATLQEILPEVLK-ADLNIILSSPEQLELFLLAQQKVP-----SKLKKLVGSV
NLFSDENVPRLVNVLKMAASSVKKDRKLPAIALDLLRLALKEDKFPRFWK-EVVEQGLLK
MQFWPASYLCFRLLGAALPLLTKEQLQLVMRGDVIRHYGEHVCTAKLPKQFKFAPEMDDY
VGTFLEGCQDDPERQLAVLVAFSSITNQGLPVTPTFWRVVRFLS--PLAL----------
--QGYVAWLQAMFLQPDLDSLVDFSTNNQKKAQDSSL-----HVPERDVFRLRKWIIFRL
VSI-VDSLHLEMEEALTEQVARFCLFHSFFVTKKPTSQIPETKQPFSFPLESQAREAVSS
AFFSLLQTLSTQ-------------FKQAPDQTRGGQPWTYRLVQFADLLLNHSH-NVTT
VTPL-TAQQRQAWDRMLQTLKELEAHSAEA-R--AAAFRHLLLLVGIHLLKG------ED
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--SED----EKLGDEAMMALDQSLASFFAEQKLRIQARRDEKNKLQKEKVLRR-DFQIRV
LDLVEVLVTKQPENVLVLELLEPLLSIIRRSLRSS----SSKQE---QDLLHKTARIFMH
HLCRARRYCHDLGERAEALHAQVERLVQQAGRQPDSPTALYHFNASLYLLRVLKGNTAEG
CVHETQEKQKAGTDPS---------------------------------------PMPTG
PQ----------------AASCLDLNLVTRVYSTALSSFLTKRNSPLTVPMFLSLFSRH-
------------------------------PVLCKSLLPILV-------QHITGPVRPRH
Q--ACLLLQKTLSMREVRSC----FEDPEWKQLMGQVLAKVTEN----------------
--------------------------LRVLGEAQTKAQHQQALSSLELLNALF---RTCK
H-KLTLDLPVLLGVLQAQQQ-------SLQQGAHS--TGPSRLHDL-----YWQAMKTLG
VQR-----------------------PKLEKKDAKE-VPSATQSPISKKRKKKGFLPETK
KRKKRKSEDGTPAE-----------DGTPAATGGSQP--PNMGRKKRNRT--KA------
------------------------------------------------------------
----------------------KVPAQAQANEIPT-TKSPAPGAP---------------
----------------------------------------------------TLSPSTP-
AKSPKLQKKNQKLSEVNGA-PGS---PAEPAGQKQHQKALPKKGVLGKSPL---SALARK
KAR--LSLVIRSPSLLQSGAKKKKA-QLRK--AGKP---

---------------------------------------------------------MES
RDPAEPMSPGEATQSGARPADRYGLLKHSREFLDFFWDIAKPEQETRLAATEKLLEYLRG
RPKGS-EMKYALKRLITGLGVGRETARPCYSLALAQLLQSFEDLPLCSILQQIQEKYDLH
QVKKAMLRPALFANLFGVLALFQSGRLVKDQEALMKSVKLLQALAQYQNHLQEQPRKALV
DILSEVSKATLQEILPEVLK-ADLNIILSSPEQLELFLLAQQKVP-----SKLKKLVGSV
NLFSDENVPRLVNVLKMAASSVKKDRKLPAIALDLLRLALKEDKFPRFWK-EVVEQGLLK
MQFWPASYLCFRLLGAALPLLTKEQLHLVVQGDVIRHYGEHVCTAKLPKQFKFAPEMDDY
VGTFLEGCQDDPERQLAVLVAFSSVTNQGLPVTPTFWRVVRFLS--PPAL----------
--RGYVAWLQAMFLQPDLDSLVDFSTNNQKKAQDSSL-----HMPERAVFRLRKWIIFRL
VSI-VDSLHLEMEEALTEQVARFCLFHSFFVTKKPTSQIPETKHPFSFPLENQAREAVSS
AFFSLLQTLSTQ-------------FKQAPGQTQGGQPWTYHLVQFADLLLNHSH-NVTT
VTPF-TAQQRQAWDRMLQTLKELEAHSAEA-R--AAAFQHLLLLVGIHLLKS------PA
ESCDLLGDIQTCIRKSLGEKPR-RSRT---KTIDPQEPPWVEVLVEILLALLAQPSHLMR
QVARSVFGHICSHLTPRALQLILDVLNPETSEDEN-DRVVVTDDSDERRLKGA-----ED
KSEE-----GEDNRSSESEEESE--GEESEEEERDGDV-DQGFREQLMTVLQAGKALGGE
DSENE----EELGDEAMMALDQSLASLFAEQKLRIQARRDEKNKLQKEKALRR-DFQIRV
LDLVEVLVTKQPENALVLELLEPLLSIIRRSLRSS----SSKQE---QDLLHKTARIFTH
HLCRARRYCHDLGERAEALHAQVERLVQQAGRQPDSPTALYHFNASLYLLRVLKGNTAEG
CVHETQEKQKASTDPS---------------------------------------SMPTG
PQ--GPTL---SPLM--KAASCLDLNLVTRVYSTALSSFLTKRNSPLTVPMFLSLFSRH-
------------------------------PVLCQSLFPILV-------QHITGPVRPRH
Q--ACLLLQKTLSMREVRSC----FEDPEWKQLMGQVLAKVTEN----------------
--------------------------LRVLGEAQTKAQHQQALSSLELLNVLF---RTCK
HEKLTLDLTVLLGVLQGQQQ-------SLQQGAHS--TGSSRLHDL-----YWQAMKTLG
VQR-----------------------PKLEKKDPKE-VPSATQSPISKKRKKKGFLPETK
KRKKRKSEDGTPAE-----------DGTPAATGGSQP--PSMGRKKRNRT--KA------
------------------------------------------------------------
----------------------KVPAQ--ANGTPT-TKSPAPGAP---------------
----------------------------------------------------TLSPSTP-
AKYPKLQKKNQKPSQVNGA-PGS---PTESAGQKQHEKALPKKGVLGKSPL---SALARK
KAR--LSLVIRSPSLLQSGAKKKK-VQLRK--AGKP---

------------------------------------------------------------
------------------------------------------------------------
-----------------------------------QVLQAFEEIPLCSILEQIKEKHNLE
TVKKKLVRNAAFGNFFGVMALFQSGRLVKDRKALLESIQLLQQLTNHQTHLRDLPRKTLI
DITSEVPETVFEEVLFDILQ-GDLSSAFTSPENLHLLLVGMQKFPGVLKPKKLKKLFGSP
TVVNKENISRLVELLKSAAKSEKEDKKLPSVVFDLLQVALKEGAFELFWN-EVVENGLLK
EKSGPVSYMCYRLLGSALPLLSMEQLQVVLKGKVMLHYGEHVVATQSPQGFKFAAEMEGY
IDTFLSGC-DDPERQLAVMMGFSTLTNQGRPVLLSASRVVRHLQ--AVAL----------
--QKYISWLKDMFLSPDLDCCLDFSSNRQKQNRQNA------DIAQQKIARLRRWIIHRL
VSI-TESA-TRKEESLVMDIARFCFFHAFFVAKKKNSQIAEASVLPSEPLNERDHTETEN
YFFGLLQTLNTLPVLGDTAKAAALREKHVHGVTADGKLWIFLLVEYANKLLSSE--HVKA
VKPF-TEEQKDIWERTLQSVKNLQKKENKSDSAKVAAFQQLLLSIAIYLFKN------QP
ETVDVLSDLLNCTERAFSKEAKKKK----KT--DNSEPGWVEVMVEILLSLLAQPSLLLR
RISKSVFVWICPNLTKRGLQLILDVFDPNQEQNEESAVVVMEES-NKKTKSAQ------N
TD----EEGSEDS--SDEDT-------TDSEDEESEE-VDDNFRSQLMKVLQAGNALKQK
EEDKS---DEELDDEAMMALDKNISALFAEQQKRIQAKKDEKDRMRKEKILRR-DFKAKV
GD----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------LLQAFEDIPLCSILGQIQEKYNLQ
TVNKGMMRPALFANLFGVLALFQSGRLVKDQEALMKSVKLLKILSHHYNHLQGQPIKVLV
DILSQVPESMFQEILPKILKGGDLNVILSSPKYLELFLLAQQRVP-----AKLESLMGSV
DLFSEENIPSLVNVLKTAANSVRKEHKLPEVALDLLRLALKENKFTLFWK-EVLEQRLLN
KPCWSASYMCFRLLGASLPLLSEEQLRLVMRGDLIRHFGEHMVISKPQNLFKIIPEISSY
VSTFLEGCQDDPKRQFAMMVAFTSITNQGLPVXXXXXRVTRLLS--SEAL----------
--QSYVTWLRDMFLQPDLDSLVDFSTANQKRAQDASF-----NVPERSVFRLRKWIIHRL
VSL-VEHLHLEKDDAVVEQVARFCFFHAFFKTKKATPQIPETKQHFSFPLDDRNRSVIIG
AFFSLLQTLSMK-------------SRQTPDLNECAKPWTYRLVQLADMLLNHSR-NVTV
VTPF-TTQQRQAWDQMMSTLKELEARSSET-R--ALAFQHLLLLVGLHLFKS------PT
ESCDVLGDIQTCIKKSMEQNPR-RSRS---RAKASQEPAWVEVMVEILLSLLAQPSNLMR
KVVRNVFGHICSHLTPRGLQLILAVLNPETNEDED-DNVVVTDDTNEKQLKRG-----ED
EDSD-----SEDNKNSDSDVDS-EDGAESEEEDRDKD-VDPGFRQQLMEVLQAGNALGGV
DSED----EEELGDEAMMALDQNLASLFAEQKLRIQARQEEKNKLQKEKQLRR-DFQIRV
LDLIEVLVTKQPEHPLILELLEPLLSIIQRSMRSKG---STKQE---QDLLHKTARIFMH
HLCRARHYCHEVGPCAEGLHAQVERLVQQAGSQADASVALYYFNASLYLLRVLKGNTAKR
YE-DGQNLPGA----E---------------------------------------PKDSE
A---------------Q-TANCLDLDFVTRVYSAALESFLTKRNSPLTVPMFLSLFSRY-
------------------------------PVICKNLLPVLV-------QHVSGPLRPRH
QAQACLLLQKTLSARELRVC----FEDPEWEQLIGQVLGKLTQT----------------
--------------------------LQTLGDAQSKGEQQREFSTLELLNILF---KTVN
HEKLSVDLTSVLGLLQSKQQ---KLQQSLQQGNHS--SGSNRLYDL-----YWQAMRMLG
VQ-----------------------RPKSEKKNVKD-VPSDSQSPISQKRKKKGFLPETK
KRKKVKSEDTTPGKDATSGQEVVTAGATPAAAGEGQPPST--GKKKRKR--VKANTPSQV
NGTPV-------------------------------------------------------
------------------------------------TKSPAPNNP---------------
----------------------------------------------------TLSPSTP-
FKSPKLQKKKEKLSQVNGGTPVS---PIEPEGKEHHQKALPTKEVLRKS---PQSALPRK
RAR--LSLVSRSPSLLQSVVKKRKVARRKMQTP------

------------------------------------------------------MAEMED
QELAEPMSPEAVA-----EADRRGLLKHSREFLDFFWDIAKPEQQTRLEATEKLLEYLRT
RPRGS-EMKYALKRLITGLGVGRENVRPCYSLALAQLLQSFEDIPLCSILQQIQEKYGLD
SVPKATMRPSLFANLFGVLALFQSGRLVKDQEALMKSVKLLQTLAQHHNHLQEQPQKALV
DILSEVPEAVLQGMLPKVLK-ADLDVVLSSPEHLALFLLARKKVP-----TKLEKMMGSV
NLFSDENIPRLVDVLKTAAASVKKEQRLSAVALGMLQLALEEDKFPRFWK-QVVEQGLLQ
KQLWPVSYMCFRLLGTALPLLSKEQLQLVLRGDLIRYFGEHSIT--VQNKYRFVPEMTDF
VNAFLEGSQDDPERQLTVLVAFSSVTNQGLPVVPTFWRVLRFLS--PRAL----------
--QGYVAWLQGMLLQPDMDSLVDFSTNSQKKAQDTTP-----HVPERAVFRLRKWIIHRM
VNL-VDHLVQEKEEALIEQLARFCLFHSFFKTKKPTGQIPETKQQFSPPLDTRGREVIGS
AFFSLLQALSTQ-------------LKQAAAQGPGGQSWTYRLVQLANTLLNHSR-NVAL
VTPF-TTEQREAWDQMLQTLKELEARSSEA-K--ATAFQHLLLLVGINLFKS------PT
ESCDLLGDIQACIKKSMEEKAQ-RPRS---KAISTQEPPWVEVMVEILLSLLAQPSHLMR
QVARSVFGHICPHLTPRALQLILAVVNPESGQDAD-DNVVVTDVAAGKQARSV-----ED
QDEDDDKN-SES---EGEEDEDEEDEDESEEEERDGD-VDPGFREQLMEVLRAGKALGGA
DSEDD---GEELGDDAMMALDQNLASLFAEQKLRIQARRDEKNKLQKEKALRR-DFQIRV
LDLVEVLVTKQPEHPLVLELIEPLLSIIRCSG---G---SSKQE---RDLLHKTARIFTD
HLFRARRCCQDVGGRAEAVHTQLEQLVQRAGRQADSSVALYHFNGSLYLLRVLKGSPAEK
CTQKSQKK-----------------------------------------------PKTRS
P----------------QATSCLDLNRVTSVYSAALSSFLTKRNSPLTVPMFLSLFSRY-
------------------------------PVICKSLLPALV-------QHLAGSTRPHN
QVQACLLLQRTLTMRELKQC----FEDHEWRQLIGQVVARLTEN----------------
--------------------------LRALGTAQTKSEQQKERSSLELLNSVL---RAVS
HEKLTVDLTGLLGVLQGQQ----NLAQSWQKGPQS--GSSSRLCDL-----YWQAMKSLG
VQR-----------------------PKQEK-DAKE-APRAPQSPVSMKRKKKGFLPETK
KRKKRKSEEAAQEE---------PKEAKPAAAAADPPPST--GKK-RKKTKAKVPAQAQV
NGTPPAKRPAPAAT-----------------------------PARTPKPQKP-------
---------------------------AQVNGAAP-ASPTEPAG----------------
----------------------------------------------------KKQRPAP-
AATPARTPKPQKPAQVNGAALAS---PTEPAGEKQRPKALPKKGVSGKSPQ---SALPRK
KAR--LSLSTRGPLLFQSGAKKKKAKVRT----P-----

------------------------------------------------------MAEMES
RGLAESVSPGGPAKSGPRPADREGLLKQSREFLDFFWDIAKPEQETRLEATEKLLDYLRA
RPQGS-EMKYALKRLITGLGVGRETARPCYSLALAQLLQSFEDIPLCSVLQQIREKHNLQ
KVKKAMMRPALFANLFGVLALFQSGRLVKDSEALMESVKLLQTLAQHYNHLQEQPQKALV
DILSEVPEATLQAILPKVLK-ADLNSVLGSPEHLELFLLAQQKVP-----EQLKELMGPV
NLFSDENIPRLVSVLKVAAASVKKERKLPAVALDLLRLSLREGKFSRFWK-EVVEQGLLK
KQFWPASYLCFRLLGAALPLLSKEQLPLVMRGDLVRHFGEHMVTAKLPNQFKFAPEMNEY
VGAFLEGCRDDAERQLAVVVAFTCITNQGLPVLPTFWRVVRSLS--PQAL----------
--KGYVAWLQNMFLRPDLDSLVDFSTSNQKKGQDASL-----HGPERAAFRLRKWVILRL
VSI-VDTLHAEKEDDVIEEVARFCFFHSFFETKKPTSQIPETEQQFSFPLESRTREVVSG
AFFSLLQTISAQ-------------FRQAPEQTQDGQPWTFRLVQFADSLLNHGR-NVTP
LTPF-SAQQRQAWDRMLQTLKELEACSPEA-KAKAKAFQLLLFLVGTHLFKS------PA
ESCDLLGDIQTCVKKCLGEKTR-RTRS---KATIPQEPPWVEVLVEILLALLAQPSHLMR
QVARTVFGHICAHLTPRALQLILDVLNPEKSQEED--SVVVTDDSE-KQLESG-----ED
KSSD-----SEDDRHSASEEDSD--EEDSAEEDRDGD-VDQGFREQLMAVLQAGKALGAV
DGEDD---DEELGDEAMMALDQNLASLFAEQKLRIQARKDEKKQLQKEKVLRR-DFQIRV
LDLIEVLVTKQPENPLVLELLEPLLDVIRRSMRTS----SSKQE---QDLLHKTARIFTH
HLCRSRHYRGP----VGSLYAQVERLGGAGGRA--GSVSLYYFNAALYLLRVLKGNAADA
CVSKTPKKRKAGP-------------------------------------------KPKG
PE--VDAL-------TAQAAGCLDLSLVTPIYSSALTSFLTRRNSPLTVPMFLSLFSRH-
------------------------------PVLCKGLLPVVI-------QHVTGQARPRH
QAQACMLLQKSLPVRELRLC----FEDPEWEQLVGQILEKVTEN----------------
--------------------------LRTLGEAQTKSEQQRELSSLGLLNTLF---RNVH
QEKLTVDLSAVLGVLQNRQE-------SLQQG-ER--PAGSSRCDL-----YWQAMKALG
VQ-R----------------------PKSEKKGAKE-GPSVTQSPVSTKRKKKGFLPESK
KRRKHQPEP-AVPE-----------EGAKAASGGDQP--PSARKKRRNRR--KA------
------------------------------------------------------------
----------------------RGPAQANGTPATK---SPPPDAT---------------
----------------------------------------------------SPSPSAP-
AKTPKLE-KKRSLSQVNGATPVP---PEAPAGRKQPLKDLPEKGVSGKSPQ---SALPRK
KAR--LSLVSKSPSLLQRGAKRKKASLKKARKP------

------------------------------------------------------------
------------------------------------------------------------
-------LKYTLKRLVVGLGATREASRPGFSLALAQVLQGLEEIPLLSALEEIKEKYSLG
KVKKKLFRNALFGNFFGVLALFQSGRLAKEPKALAECVQLLQSLSEHHAHLKDLPRKTLA
DIVAEIPETVFEEVLFSVLE-DELSSAFHTPGQLYLLLVGIQKFPRVLRPEKLKALLGTS
AVVTEENVPRLVEVLKMAAKTERKDRVLPTVGLDLMKVALKEGRFELFWT-DVVENGLLA
DHAGPCSYMCYRLLGSALPLLSLKQLKMVLQGEVMRHYGIHVVSTKLPNRFKFAPEMELL
VSSFLEGC-DDPKKQLAVMVGFSTLTNHGYPVVPSFWRVVRHLL--PDTL----------
--LNYISWIKSMFLAPDLDCCVEFATKRQEQNEKKTD-TSCSELTEHSVTRLRKWLIARL
VGI-AENPQIKREEEFVTDIARFCFFHAFFKTRKPTSKIPETETIPSVPLNESTRAVTAD
SFFSLLQHLNTMPALGESAEAEEMRKKHLHGLAASGEPWIYLAVQYANTLLSNKK-HVEA
VAPF-SEEAQFAWDRMLQTVEALRRREQKSLTLKTTAFQHLLLLVGIHLFKS------PA
ECVNLLNDLQNCTKRAFGEKTKKKTSV--SAGKFHSEKIVLEVIVEVLLSLLAQSSALIR
RVCRSVFALVCQHMTEAALQLILDVLDPQQDQDEESAVVVVEEA-QKTKKKSL-----PD
EESD--DGSSGES--SAEEDSSEEDNAPETDSEAEGE-ADEAFRSMLTNVLQAGNAL---
GGDDS---DEDFDDETMMSLDGNLSALFAEQRKRVQAKKDEKEKIRKEKILRR-EFKIKV
LDLVEVFLTKQPENPLVFRVIEPLLSVIEQSMSSD----SGKQE---QDFLRKTADIFTN
SLCRSKQYCRNVGPIQEELHNQLESLVKRACKQRDSTVALYCFSASLYLCRVLKGNVGAH
EASPKKKPKS-----GG-------------------------------------------
---------GSDVPVAQPPVSSLDLDRAASAYMEALSLFFSKRKNPLTGSMFLDLFERH-
------------------------------PIMCKQLIPTVV-------KSITEGARQPQ
QAQACMLLQKALQMRDFKLS----LSEKEWEELMRDGTKQVTKT----------------
--------------------------LTAMGEFKIKVDQEKVIRCLELLSCLI---KMSN
KQGPPLDLTELPAVLRVLGE---------QPGF----GKSARLNDL-----YWNVMNFLG
FAR-----------------------PAKEKAPPK---PTADPDPAPKKRKKKGFLPATK
IRKNRKKATPVSSQEE--------------EGAKSGRKEAVAGKKKKR-KR---------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

---------------------------------------------------------VEE
QEFAERMSWEEVT-----EADRRGLLEHSREFLDLFWDIAKEEQQTRLEATEKLLEYLRA
RPEGS-EMKYALKRLITGLGMMREHARPCYSLALAQLLQCFEDISLLSILQQIQEKYKLD
SLTKATMRPSLFGNLFGVLALFQSGRLVKDLEALLECVKVLQALAQHHNHLQEQPRRALV
DILSEVPDNLWQGLLPKVLS-TDLDVILSSPEHLELFLLARKKAP-----AKLQKLMGSV
NLFSNEYIPRLVEVLRRAAASMKKEQKLPPVTLGMLRLALEEDKFPQFWK-QVVEQGLLQ
KQLWPVNYMCFRLLGTALPLLSKEQLQLVLRGDLARLMGEHMVTSQIQNKFKFLPELTKL
VVTFLEGSQDDPEKQLAVLVDLTSITNQGLPAIPTFWHVVRFLS--PQAF----------
--QGYVAWLQEMFIQPKLDSLLDFSTGVQKKAQKAAP-----SMPGRAVFRLRKWIIHRL
VSM-IDHMVQEKDEALINQLARFCLFHSFFKTKKPVAQIPETKHQFSVPLEARDREIISD
GFFSLLQALSSP-------------VREAAAQALGGQLWTHRLLQLANTLLNHSR-NVTP
VTPF-TTQQREAWDQMLQTLKELEARSSEA-K--ATAFQHLLLLVGINLFKS------PA
ESCDLLGDIQACIKKSMEETAQ-RPRA---KKTNSEEPPWVEVMVEILLTLLSKPSHLMR
RVARNVFGHICSHLTHRALELILVVVNPESSQDAE-DNVVVTDDAAEEQVRSA-----ED
KDKDDEDKNSDS---ED------EEEEDESEEERDKD-VDPGFREQLMEVLRAGKALGEG
DSEDD---GEELDDEAMMALDKNLASLFAEQKLRIQARQDGKLKLQKEKALRR-DFQIRV
LDLIEVLVSKHPENALILELIEPLLSIIRRSS---G---GSKQE---RDLLHKTARILTE
NLFRTRQCYHDVGARADSVQAQLEQLVQQASRQADSSIAFYYFNASLYLLRVLKMSPAPK
SVPKKRQKKQKASP-----------------------------------------RHSEG
P----------------QITSCLDLMRVTSAYSAALSSFLTKRNSPLTIPMFLCLFSRH-
------------------------------PMICKNLVPVMV-------QHIAGPTRPHN
Q--ACQLLQKTLCISELKVC----FEDAEWEQLISGIVAQAAKN----------------
--------------------------LQALGTPQTKPEHQREASSLELLNNVL---RTIS
YKKLTVDLTGLLGMLQSQQQ---KMTENLQQGEHT--NTSSRLQDL-----YWQAMKYLG
AQR-----------------------PKLEKEDTKK-VPSIPQSPISMKQKKKGFLPETK
KRKKRKAEDMAQEA---------P---SPAATAADPPPST--GKK-RKKMKAKLPAQAQV
NGTPPAKSPVPSDS-----------------------------PAKTPKQQKQ-------
---------------------------Q--------------------------------
------------------------------------------------------------
---------APKPAQVSEAIPIS---PAEPVAEKPHLKPLPKKRISGKSPL---SPLPRK
KAR--MSLATRGPLMFQFGAKKKKTLRFT----MSSSKK

------------------------------------------------------MAEIKS
CDVAEPVSTQDAT-----QADRHGLLEHSREFLDFFWDIAKPHQETRLEATEKLLDYLRT
RPT-GSEMKYALKRLITGLGTGRETARPCFSLALAQLLQSFEDIPLCSILQQIQEKYDLE
KVKKAMMRSALFANLFGVLALFQSGRLVKDQEALLKSVKLLQTLAQHYNHLHSQPLKALM
DILSEVPEATFQEILPEVIT-GDLNVVLSSPHHLELFLLAQQKVP-----TKLKKLMGSV
DLLSDENIPSLVNVLKMVATSVKKEHKLPGLALNLLRLALKEDRFSRFWK-EVVEQGLLK
KQSWPACYLCFRLLGAALPLLSTEQLQLVMQGDLIRLFGEHTVTTKLPNQFKFVPEMSVY
IGTFLEGSQDDPERQLAVLVAFSSITEQGLPVMPTFWRVTQFLN--PQAL----------
--QDYVAWLQDMFLKPNLDSLIEFSTTNQKKSQDASL-----NMPERAVYRLRKWIIHRM
VNI-VDQLYQEKEEALIDQVARFCLFHSFFKTKNPVDQIPETKQQLSIPLDVRTRDFIIT
AFFSLLQTLSIK-------------FKQAPDQTQGGKSWTYHLVQLADTLLNHSG-NVDA
VTPF-TTEQRQAWDQMLETLKELEARSSEA-K--ATAFQHLLLLVGIHLFKS------PT
ESCDLLGDIQTCIKKSMGEKSRRRSRA---KATDSQEPPWVEVMVEILLSLLAQPSHLMR
QVARNVFGHICPHLTPRALQLVLDVLNPETNQDED-DNVVVTDDSDEKQLMDS-----EN
ENKD-----SEDNRNSESEEDS-EDGEESEEEERDED-VDPGFRQQLMAVLHAGKALGGV
DGEE---DEEELGDEAMMALDQNLASLFAEQKLRIQARKDEKNKQQKEKALRV-AFQIRV
LDLIEVLVTKQPENPLVLELLEPLLSIIRRSMRSSS---TARQE---QDLLHKTARIFMQ
HLCRARRYCHDLGDRVEALHTRVEQLVQQASRQADSSVALYYFNASLYLLRVLKGNTVKK
SGLCSHPHP------------------------------------------------AFH
L---------------AQAASCLDLNLVTSIYSGALSSFLTKRNSPLTAAMFLNLFSRF-
------------------------------PVICKNLLPILI-------QHVAGPARPRH
QVQACLLLQKTLPRGELRPC----FEESEWEQLIVQILVKVTEN----------------
--------------------------LRTLGEAQNKSEHQKELSSLGLLNILL---KN--
HKRRAGNLTTLLDVLQGRQQ---ILQQSLQQGEHL--IGSTRLHDL-----YWQALKMLG
VQYELKVEVALPSLDTFLPCSLPPRRPKLEKKDAKE-VSSATQSPVSMKRKKKGFLPETK
KRKKRKSEDV-----------------TAIATGEDQPPST--GKRRRKKIKAK-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--TSKLQNRSEKLSQVNGVTPTS---PAEPAGKKQRQKALPKKEVSGKS---PQSALPRK
KAR--LSLV-RSPSLFQGGAKRKRMMRKKGRAAQT----

---------------------------------------------------------MET
QNLAEPEAPGEATKTGARPTDRHGLLQHSREFLDFFWDIAKPEQETRLKATEKLLEYLRT
RPKGS-EMKYALKRLINGLGVGRETARPCYSLALAQLLQSFEDIPLCSVLEQIQEKYNPQ
KVKKTMVRPALFAHLFGVLALFQSGRLVKDQEALTKAVKLLQALAQYRNHLQEQPQKALV
DILSEVPEATLKELLPKVLK-ADLGVVLSSPENLELFLLAQQKVP-----AKLEKLLGSV
DLFSAENIPRLVNVLKTAAASVKER-KLP-VALNLLHVA-LENKFPQFWN-EVLEQGLLK
KQFPPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVPDRFKFAPEMDEY
VGAFLEGCRTDPERQLAVLVAFSSITNQGHPVVPTFWRVVRFLS--PHAL----------
--KDYVAWLRDMFLQPNLDSLVDFSTSNQKKSQDPSL-----HVPERTVFRLRKWIILRL
VSI-VENSHVEKEEALVEEVARFCLFHSFFETKKPTSEIPETEQQLSFPLESRTREVVCS
AFFSLLQALSPQ-------------CRQVPGQTPNGQSWTYRLVQFADMLLNHSH-NVAT
VTPF-TAQQRQAWDRMLQTQKDLEAHSSEV-K--ATAFQHLLLLVGIYLFKS------PA
ESCDLLGDIQTCIEKSLEGKPR-RTRS---KAVDPQEPPWVEVLVEILLSLLAQPSHLMR
QVARSVFGHICSHLTPRALQLILDVLNPDKSQDED-DNVVVTDDSDEEQLKTA-----QN
KSKDDSD----GEEEKEEEEEEEEEEEESDEEARDEE-VDQGFREQLMAVLQAGKALGGV
DSEDE---EEELEDEAMMALDQNLASLFAEQKLRIQAKKDEKNKLQKEKVLRR-DFQIRV
LDLVEVLVTKQPENPLVLELLEPLLTIIRRSMRTS----SSKQE---QDLLHKTARIFTH
HLCRARHYCHDVGNLVEALHAQVERLVQ-ASRQADSSITLYYFNATLYLLRVL-GNTASA
LPPKTPKKQKASA-------------------------------------------KAKG
PE----------------ATSCLDLKRVTVVYSSALSSFLTKRNSPLTVPMFLSLFCRH-
------------------------------PVLCKSLLPIMV-------QHVTGPARPRQ
--QACLLLQKALSMGELKLC----FEHPEWEQLISQVLAKVTEN----------------
--------------------------LRTLGKAQTKSEQQRELSSLELLITLL---KAIH
LQKLAVDLTAILGLLQGLQP---SLQQSLQQGAHS--AGSSRLYDL-----YWQAMKFLG
VQR-----------------------PKSEK-DAKE-TPSDTQSPVSMKRKKKGFLPETK
KRKKRKPEDATEQ------------EAKPVTSSENQP--PSSGKKKRRRT--KA------
------------------------------------------------------------
----------------------TASAQSQMNGKPA-AG----------------------
----------------------------------------------------SPVPNTL-
VTSSRTSDTP--LQ-APVCLPR-------PENQKKHQKVLSKMEVSGKSPQ---PALSQK
KTK--LSLANGSPSLHRSGAKKKKVQ-------------

---------------------------------------------------------MGS
RELAEPLSPGEATQSGARPADRHGLLKHSREFLDFFWDIAKPEQETRLAATEKLLEYLRG
RPKGS-EMKYALKRLITGLGVARETARPCYSLALAQLLQSFEDLPLCSILQQIQEKYDLC
EVKKTMLRPALFANLFGVLALFQSGRLVKDQEALMKSVKLLQALAQYQNHLQEQPGKALL
DVLSEVSVATLQEILPEVLK-ADLNAILSSPEQLELFLLAQQKVP-----SKLKKLVGSV
NLFSDENVPRLVNVLKMAAASVKKDRKLPAIALDLLRLALKEDKFPRFWK-EVVEQGLLK
TQFWPASYLCFRLLGAALPLLTKEQLQLVLRGDVIRHYGEHVCTAKLPKQFKFAPEMEDY
VGTFLEGCQDDPERQLAVLVAFSSVTNQGLPVAPTFWRVVRFLS--PPAL----------
--RGYVAWLQDMFLQPDLDSLVDFSTNNQKQAQDASL-----HVPERAVFRLRKWIIFRL
VSI-VDSLHLEMEEALTAQVARFCLFHAFFVTKKPTSQIPETKQPFSFPLESQAREAASS
AFFSLLQTLSMQ-------------LKQATDQTRGGQPWTYHLVQFADLLLNHSH-NVTT
VTPF-SAQQRQAWDRMLQTLKELEAHSSEA-R--AAAFQHLLLLVGIHLLKS------PA
ESCDLLGDIQTCIRKSLGEKPR-RSRT---KAIDPQEPPWVEVLVEILLALLAQPSHLMR
QVARSVFGHICSQLTPRALQLILDVLNPETSEDE--DHVVVTDDSDERRLKGA-----ED
KSED-----GEDNRSSESEEESE--GEESEEEERDGD-VDQGFREQLMTVLQAGKALGGE
DSEDE----EELGDEAMMALDQSLASLFAEQKLRVQARRDEKNKLQKEKALRR-DFQIRV
LDLVEVLVTKQPENALVLELLEPLLSIIRRSLRSS----SSKQE---QDFLHKTARIFTH
HLCRARRYCHDLGERAEALHAQVERLVQQAGRQPDSATALYHFNASLYLLRVLKGSTAEG
CMRETREKQKAGTDPS---------------------------------------PVPTG
PQ----------------AASCLDLNLVTRVYSSALSSFLTKRNSPLTVPMFLSLFSRH-
------------------------------PVLCKRLLPILV-------QHVTGPVRPRH
Q--ACLLLQKALSLREVRSC----FEDPEWKQLMGQVLAKVTEN----------------
--------------------------LRVLGEAQTKAEHQQALSSLELLNALF---RTCK
QEKLTLDLTVLLGVLQGQQQ-------SLQQGAHS--TGSSRLHDL-----YWQAMKTLG
VQR-----------------------PKLEKKGAKE-VPSATQSPISKKRKKKGFLPETK
KRKKRKSEDGTLAE-----------DGTPVATGGSQP--PSMGRKKRNRT--KA------
------------------------------------------------------------
----------------------KVPAQ--ANGTPA-TKSPAPGTP---------------
----------------------------------------------------TLSPSTA-
AKSPKLQKKSQKPSQVNGA-PRP---PVEPAGQKQPQKALPEKGVVGKSPL---SAPARR
KAR--LSLVSRSPSLLQSGAKKKT--LR-F--TISSPKK

------------------------------------------------------MAEMKS
PTKAEPAPPAEAV-----QDDRRDLLEHSREFLDFFWDIAKPEQETRLQATEKLLEYLRT
RPS-GSEMKYALKRLVTGLGMGREAARPCYSLALAQLLQSFEDIPLCSILTQIQEKYNLQ
TANKAMLRPALFANLFGVLALFQSGRLVKDQEALMKSVRLLNILSHHNNHLQGQPMKVLV
DILSKVPESMFEEILPKVLK-DDLKVILSSPKYLELFLLAKQRVP-----AKLESLVGSV
DLFSEENIPSLVNVLKMAAKSVRKEQKLPDVSLSLLRLSLKENKFTLFWK-EVVEQGLLK
KLSWSTSYMCFRLLGASLPLLSEEQLQLVMRGDLIRHFGEHAVISKPQNLFKFVPEISRY
VSIFLEGCQDDPKRQFAMMVAFTSITNQGLPVMPTFWHVTRFLS--SEAL----------
--QSYVVWLRDMFLQPDLDSLVDFSTTNQKRAQDASI-----NVPERCVLRLRKWIIHRL
VSL-VDHLHLEKDDAVVDQVARFCLFHAFFKTKKATPQIPETKQHFSFPLDNRNRSVIIS
SFFSLLQTLSVK-------------FRQSPDLNESGKPWTYRLVQFADMLLNHSR-NVTL
VTPF-TTQQRQAWDQMMSTLKELEAQSSET-R--SIAFQHLLLLVGLHLFKS------PT
ESCDVLGDIQTCIKKSMEQNPR-RSRS---RAKASQEPVWVDVMVEILLSLLAQPSNLMR
QVVRNVFGHICSHLTPRGLQLILAVLIPETNEDED-DNVVVTDDTSEKQLEHG-----ED
EG-------SEDDKNSDSDMDS-DDGAESEEEDRDKD-VQPGFRQRLMEVLQAGNALGGV
DSED----EEELGDEAMMALDQNLSSLFAEQKLHIQARQEEKNKVQKEKKLRR-DFQIRV
LDLIEVLVTKQPEHPLVLELLEPLLSIIQHNMRSKG---SSKQE---QDLLHKTARIFMH
HLCRARHYCHEVGPCAEALHAQVERLVQRAGSQTDTSVALYCFNASLYLLRVLKGNTAKK
HQ-DGQMLQGADTKPE---------------------------------------PKDPE
A---------------Q-TANCLDLNFVTRVYSAALESLLTKRNSPLTVPMFLSLFSRY-
------------------------------PVICKNLLPILL-------QHVADPLRPRH
QAQACTLLQKTLSARELRVC----FEDPEWEQLIGQVLEKVTQT----------------
--------------------------LHTLGEAQSKGEHQRELSTLELLNSLF---KTVN
HEKLSVDLTSLLGMLQSKQQ---KLQQNLKQGNHS--SGSNRLYDL-----YWQAMRMLG
VQ-----------------------RPKSEKKNARD-IPSDSQSPISMKRKKKGFLPETK
KRKKLKSKDATPEKDAASGQDVVMADAAPAAGGTDQPPST--GKKKRKR--GKANTPSQV
NGTPV-------------------------------------------------------
------------------------------------TKSPAPNDS---------------
----------------------------------------------------TLSPSTP-
AKTPKLQKEKEKLSQVNGTTPVS---PIEPEGKKHYQKALPTKEVLRKT---PQSSLPRK
RAR--LSLVNRSPSLFQSGVKKRKVARKKVQTP------

---------------------------------------------------------MGS
RELAEPLSPGEATQSGARPADRHGLLKHSREFLDFFWDIAKPEQETRLAATEKLLEYLRG
RPKGS-EMKYALKRLITGLGVARETARPCYSLALAQLLQSFEDLPLCSILQQIQEKYDLC
EVKKTMLRPALFANLFGVLALFQSGRLVKDREALMKSVKLLQALAQYQNHLQEQPGKALL
DVLSEVSVATLQEILPEVLK-ADLNAILSSPEQLELFLLAQQKVP-----SKLKKLVGSV
NLFSDENVPRLVNVLKMAAASVKKDRKLPAIALDLLRLALKEDKFPRFWK-EVVEQGLLK
MQFWPASYLCFRLLGAALPLLTKEQLQLVLRGDVIRHYGEHVCTAKLPKQFKFAPEMENY
VGTFLEGCQDDPERQLAVLVAFSSVTNQGLPVAPTFWRVVRFLS--PPAL----------
--RGYVAWLQDMFLQPDLDSLVDFSTNNQKKAQDASL-----YVPERAVFRLRKWIIFRL
VSI-VDSLHLEMEEALTAQVARFCLFHAFFVTKKPTSQIPETKQPFSFPLESQAREAASS
AFFSLLQTLSTQ-------------LKQATDQTRGGQPWTYHLVQFADLLLNHSH-NVTT
VTPF-SAQQRQAWDRMLQTLKELEAHSSEA-R--AAAFQHLLLLVGIHHLKACWLLWDPD
HPCQALPLL--------------SVKA---GVGYPQEPPWVEVLVEILLALLAQPSHLMR
QVARSVFGHICSQLTPRALQLILDVLNPETSEDE--DHVVVTDDSDERRLKGA-----ED
KSED-----GEDNRSSESEEESE--GEESEEEERDGD-VDQGFREQLMTVLQAGKALGGE
DSEDE----EELGDEAMMALDQSLASLFAEQKLRVQARRDEKNKLQKEKALRR-DFQIRV
LDLVEVLVTKQPENALVLELLEPLLSIIRRSLRSS----SSKQE---QDFLHKTARIFTH
HLCRARRYCHDLGERAEALHAQVERLVQQAGRQPDSATALYHFNASLYLLRVLKGSTAEG
CVRETREKQKAGTDPS---------------------------------------P----
----GPTLSLLK---GGQAASCLDLNLVTRVYSSALSSFLTKRNSPLTVPMFLSLFSRH-
------------------------------PVLCKRLLPVLV-------QHVTGPVRPRH
Q--ACLLLQKALSLREVRSC----FEDPEWKQLMGQVLAKVTEN----------------
--------------------------LRVLGEAQTKAEHQQALSSLELLNALF---RTCK
QEKLTLDLTVLLGVLQGQQQ-------SLQQGAHS--TGSSRLHDL-----YWQAMKTLG
VQR-----------------------PKLEKKGAKE-VPSATQSPISKKRKKKGFLPETK
KRKKRKSEDGTLAE-----------DGTPAATGGSQP--PSMGRKKRNRT--KA------
------------------------------------------------------------
----------------------KVPAQ--ANGTPA-TKSPAPGTP---------------
----------------------------------------------------TLSPSTA-
AKSPKLQKKSQKPSQVNGA-PRP---PVEPAGQKQPQKALPEKGVVGKSPV---SAPARR
KAR--LSLVSRSPSLLQSGAKKKK--TLRF--TISSPKK

---------------------------------------------------------MGS
REPAEPLSPGDATQNSARPADRHGLLKHSREFLDFFWDIAKPEQETRLAATEKLLEYLRA
RPKGS-EMKYALKRLITGLGVGRETARPCYSLALAQLLQSFEDLPLCSILQQIQEKYDLH
QVKKSMVRPALFGNLFGVLALFQSGRLVKDQEALRKSVKLLQALAHHQNHLQEQPRKALV
DILSEVSEATLQEMLPEVLS-TDLDAMLSCPEQLGLFLLAQQKVP-----SRLKKLVGSV
NLFSDENVPRLVNVLKMAASSVKKERKLPTVALELLRLALKEDKFLQFWK-GVVEQGLLK
LQFWPASYLCFRLLGAALPLLTKEQLQLVMRGDVIRHYGEHTCTAKLPNQFKFAPEMEEY
VGTFLEGCRDDPERQLAVLVAFSTTTNHGLPVVPTFWRVVRFLS--PRAL----------
--QGYVAWLQDMFLQPDLDSLIDFSTNNQKKAQDASL-----HVPERAVFRLRKWIILRL
VSL-VDSLHLEMEEALTEQVARFCLFHSFFVTKKPTSQIPETRQQLSLPLESQAREAVSS
AFFSLLQTLSTQ-------------FKPASEQTRGGQPWTYRLVHFADLLLNHSH-SVTP
VTPL-TAQQRQAWDRMLQTLKELEAPSSEP-R--AAAFQHLLLLVGIHLFKS------PT
ESCDLLGDIQTCIRKSLGERRH-RSRT---KAIDPQEPPWVEVLVEILLALLAQPSHLMR
QVARSVFGHVCSHLTPRALQLILDVLNPETSEDED-DHVVVTDESDERWLKAS-----ED
KSED-----SEENRGSESEDESD--GGESEEEERDGD-VDQGFREQLMSVLQAGKALGGE
ESEDE----EELGDEAMMALDQSLASLFAEQKLRIQARRDEKSKLQKEKALRR-DFQIRV
LDLVEVLVTKQPENVLVLELLEPLLRIIRRSLRSS----SSKQE---QDLLHKTARIFTH
HLCRGRRYCHDLGDRVEALHGQVARLVEQAGRQPDSSTALYHFNASLYLLRVLKGGTAEG
HLHETQEELEAGTNPS---------------------------------------PVPEG
P----------------QAAGCLDLNLAMRVYSSALSSFLTKRHSPLTVPMFLSLFSRH-
------------------------------PVLCKSLLPVLV-------QHITGPGRPRQ
Q--ACLLLQKTLSMREVRSC----FQDPEWKQLIGQVLTKVTEN----------------
--------------------------LRTLGEAQTKAEHQQALSSLELLNTVF---RTCK
HEKLTLDLTVLLGVLQGQQQ-------GLRQGAHC--TGSSRLLDL-----YWQAMKTLG
VQR-----------------------PKLEK-DAKE-IPSATQSPISRKRKKKGFLPETK
KRKKHTSQ-----------------DGTPAATGGSQP--PSTGRK-RNRT--KA------
------------------------------------------------------------
----------------------KGPAR--ANGMPS-TKGPAPGTP---------------
----------------------------------------------------TLSPSPP-
AKSPKLQKKNQKLSQVNGA-PGS---PTKPAGQKKHHEAPPKKGVLDKSPP---STLARK
KAR--PPLVSRSPSLLQSGTKKK-KTQLRK--AGKP---

------------------------------------------------------MAEPAS
VEVTEPLAPGEAQKSGARPADRHGLLKHSREFLDFFWDIAKPQQETRLEATEKLLEYLRA
KPKGSSEMKYALKRLITGLGGGREAARPCYSLALAQLLQSFEDIPLGSILQQIQERHDLQ
KVKKGMMRPALFGNLFGVLALFQSGRLVKDSEALMKSVKLLQALGQHYNHLQEQPQKALV
DILSQVPETALQEILPKVLK-PDMNSVLGSPEHLELFLLAQQKVP-----KKLEKLMGPV
NLFSDENIPRLVTVLKTVANSVKKERKLPTVALDLLRLALQEDKFPWFWK-EVVEQGLLK
KQFWPASYLCFRLLGAALPLLSKEQLQLVMQGDLIRHYGEHMVTAKLPKHFKFAPEMNEY
VGAFLEGCKDDPERQLALVVAFTSITNQGLPVVPTFWRVVQFLS--PTAL----------
--KGYVAWLRDMFLQPDLDSLVDFSTYNQKKTQDASF-----HGPERAVFRLRKWIILRL
VSI-MDNLHVEKEEALIEEVARFCFFHSFFETKKPTSQIPESEQHFTLALDGRTREVVCS
AFFRWVQTLSTQ-------------FRLAPEQTADGRPWTYHLVQFADILLNHSR-NVAP
LTAF-TTQQRQAWDRMLKTLKELDTLSSEA---KATAFQHLLLLVGIHLFKV------VQ
GSCGLLQVFSSLRRQD---SLL-ASRD---RLKLVETPPWVEVLVEILLSLLAQPSHLMR
QVARSVFGHICSHLTLRALQLILNVLNPEESQDED-DNVVVTDDSEEQPRGGVTHGHPQD
KSSDGEDSKGSKG--SES--EEESD-DDSDEEDRDGD-VDQGFREQLMAVLQAGKALGGA
DSEDD--DDEELGDEAMMALDKSLASLFAEQKLRIQARKEEKNKLQKEKALRR-DFQIRV
LDLIEVLVTKRAFTHLFLQCLAQGPQSHRRPQGP---------C---SWQSRLGARLAGH
HLCRSRHYCRTAGDPAETLSPA----GGAGGGQADSSVALYHFNASLYLLRVLRGSTVDK
PARKAQKKEKASKD---------------------------------------AS-----
-----------SHPQGPEAASCLDLSLVTPIYSSALSSFLTKRNSPLTVPMFLSLFARH-
------------------------------PMLCKNLLPIVV-------D-----TRPRH
QVQACLLLQKTLPTRELRLC----FKDPEWKQLLGQTLGKVTEI----------------
--------------------------SGTLGEAETKSGHQKDLAALELLNTLF---RNFH
HELYSVLGQATLGVLQSRQP---RLPPRLKHGG-P--AGASRLHDL-----YWQAMKFLG
VQR-----------------------PKPEKDTKEA-PQATQQSPVSMKRKKKGFLPETK
KRKKRKPEATTQEA----------AVAKPEATSGDQPPSA--GKKKKKKKKMKKT-----
------------------------------------------------------------
----------------------KSPAQSQVNGTPA-AKSPTPEPP---------------
----------------------------------------------------VVSPSTP-
TKTPKPQKKSQKLSQMNEPTPLPRQSPEEPAAKKRQ-KKLPQKGVSGKSPQ---SALPRK
KAR--LSLASRSPSLLQSGAKKV-QL-RLSTS--VTTP-

------------------------------------------------------MAEMGS
AEVAEPAPAGGAT-----SADRHGLLEHSREFLDFFWDIAKPHQQTRLEATEKLLAYLRA
RPE-GSEMKYALKRLVTGLGVGRETARPCYSMALAQLLQSFEDISLCSILEQVQEKYALN
TAKKTMIRPVLFANLFGVLALFQSGRLMKDQKALMKSVKLLQVLSHHYNHLQGQPMKALV
DILSEVPEATFEEILPKVLR-ADLNVVLSSPKHLEIFLLAKQKVP-----AKLESWMGSV
DLFTDENIPRLVNVLRLVAASVKKENKLPVVALDLLRLALKEKKFLQFWR-EVVEQGLLA
KPSWPASFMCFRLLGAALPLLSNEQLQLVMRGDLARHFGEHMVMAKLSNQSKFVPEMSEY
VGTFLEGCQDDPERQLSVLVAFSSITNQGLPVMPTFWRVTRFLS--PQAL----------
--QDYVAWLQGMFLQPNLDSLVDFSTANQKKAQDASL-----NSPERAIFRLRKWIIHRL
VSL-LDTLHLEKEEALIEQVARFCLFHSFFKTKKPTSQIPETKQQFSIPLDSRTREFFTG
AFFSLLQTLSTK-------------LRHIPDQAQGGHHWIYRLVQLADTLLNHSR-NVAI
VTPF-TAQQRQAWDQMLETLKELEARSSET-K--ASAFQHLLLLVGIHLFKS------PT
ESCDLLGDIQTCIKKSMGEKTR-RSRS---KAINSQEHPWVEVMVEILLSLLSQPSNLMR
QVARSVFGHICSHLTPRALQLILNVLNPETNQDED-DVVVVTDDSDEKQQKDA-----ED
EGSD-----SKDE-DSESEA-D-SEGEESEEEERDEH-VDPGFRQQLMEVLQAGKALGGT
DSDE-----EELSDEAMMALDENLSSLFAEQKLRIRARREEKNKLQKEKALRR-DFQIRV
LDLIEVLVTRQPENPLVLELLEPLLNIIRSSMRSS---SSSKQE---QDLLHKTARIFMH
HLCRSRHYCHNVGPCAAALHTQVERLVQQASQQADSSVALYYFNASLYLLRVLKGNAK-K
HTLEGQQCQGASARGG---------------------------------------PEDPG
P---------------Q-ATNCLDLDLVTPVYLAALSSFLTRRNSPFTIPMFLSLFSRY-
------------------------------PMICKSLLPVLL-------QRMSGSTRARQ
QAHSCLLLQKTLSARELRAC----FEDPEWEQLIGQVLAKVTEN----------------
--------------------------LCTLGEAQSRAEHQKQLTSLELLNTLF---KIIH
HEDVTVDLSALLGVLRGQQ-------QSLQQGEHS--AGSNRLHDL-----YWQAMKMLG
VQ-----------------------RPKIEKKNTKE-APSASESPLSMKRKKKGFLPETK
KRKKRKLEGPTPEEGAT------PEAATPPATGGNQPPST--GKKKRKRGKAKVLAQPQV
NGTPA-------------------------------------------------------
------------------------------------TKSPAPNTL---------------
----------------------------------------------------TLSPSTP-
AKTPEPKK-GKRPSQVNGDTPVT---PTEPSGKKQRQKALSNKGISVKS---PQSALSRK
KAR--MSVV-KSPSLFQSGAKKKKLLRKKLRTP------

---------------------------------------------------------MGS
RELAEPLSPGEATQSGARPTDRHGLLKHSREFLDFFWDIAKPEQETRLAATEKLLEYLRG
RPKGS-EMKYALKRLITGLGVARETARPCYSLALAQLLQSFEDLPLCSILQQIQEKYDLH
QVKKTMLRPALFANLFGVLALFQSGRLVKDQEALMKSVKLLQALAQYQNHLQEQPRKALV
DVLSEVSVATLQEILPEVLK-ADLNTILSSPEQLELFLLAQQKVP-----SKLKKLVGSV
NLFSDENVPRLVNVLKMAAASVKKDRKLPAIALDLLRLALKEDKFPRFWK-EVVEQGLLK
MQFWPASYLCFRLLGAALPLLTKEQLQLVLRGDVIRHYGEHVCTAKLPKQFKFAPEMEDY
VGTFLEGCQDDPERQLAVLVAFSSVTNQGLPVAPTFWRVVRFLS--PPAL----------
--RGYVAWLRDMFLQPDLDSLVDFSTSNQKKAQDASL-----HVPERAVFRLRKWIIFRL
VSI-VDSLHLEMEEALTAQVARFCLFHAFFVTKKPTSQIPETKQPFSFPLESQAREAASS
AFFSLLQTLSTQ-------------LKQATEQTRGGQSWTYHLVQFADLLLNHSH-NVTT
VTPF-SAQQRQAWDRMLQALKELEAHSSEA-R--AAAFQHLLLLVGIHLLKS------PA
ESCDLLGDIQTCIRKSLGEKPC-RSRT---KAIDPQEPPWVEVLVEILLALLAQPSHLMR
QVARSVFGHICSQLTPRALQLILDVLNPETSEDE--DHVVVTDDSDEQRLKGA-----ED
KSED-----GEDNRSSESEEESE--GEESEEEERDGD-VDQGFREQLMTVLQAGKALGAE
DSEDE----EELGDEAMMALDQSLASLFAEQKLRVQARRDEKNKLQKEKALRR-DFQIRV
LDLVEVLVTKQPENALVLELLEPLLSIIRRSLRSS----SSKQE---QDFLHKTARIFTH
HLCRARRYCHDLGERTEALHAQVERLVQQAGRQPDSATALYHFNASLYLLRVLKGSTAEG
CGRETREKQKAGTDPS---------------------------------------PVPTG
PQ--GPTLSLLK---GGQAASCLDLNLVTRVYSSALSSFLTKRNSPLTVPMFLSLFSRH-
------------------------------PVLCKRLLPILV-------QHVTGPVRPRH
Q--ACLLLQKALSLREVRSC----FEDPEWKQLMGQVLAKVTEN----------------
--------------------------LRVLGEAQTKAEHQQALSSLELLNALF---RTCK
QEKLTLDLTVLLGMLQGQQQ-------SLQQGAHS--TGSSRLHDL-----YWQAMKTLG
VQR-----------------------PKLEKKGAKE-VPSATQSPISKKRKKKGFLPETK
KRKKRKSEDGTLAE-----------DGTPAATGGSQP--PSMGRKKRNRT--KA------
------------------------------------------------------------
----------------------KVPAQ--ANGTPA-TKSPAPGIP---------------
----------------------------------------------------TLSPSTA-
AKSPKLQKKSQKPSQVNGA-PRS---PVEPAGQRQHQKALPEKGVLGKS-L---SAPARR
KAR--LSLVSRSPGLLQSGAKKKK--AQ-L--RKSGKP-

---------------------------------------------------------MGS
RELAERMSPGEATQSGARPADRHGLLKHSREFLDFFWDIAKPEQETRLAATEKLLEYLRG
RPKGS-EMKYALKRLITGLGVARETARPCYSLALAQLLQSFEDLPLCSILQQIQEKYDLH
QVKKTMLRPALFANLFGVLALFQSGRLVKDQEALMKSVKLLQALAQYQNHLQEQPRKALV
DILSEVSVATLQEILPEVLK-ADLNTILSSPEQLELFLLAQQKVP-----SKLKKLVGSV
NLFSNENVPRLVNVLKMAASSVKKDRKLPAIALDLLRLALKEDKFPQFWK-EVVEQGLLK
MQFWPASYLCFRLLGAALPLLTKEQLQLVLRGDVIRHYGEHVCTAKLPKQFKFAPEMEDY
VGTFLEGCQDDPERQLAVLVAFSSVTNQGLPVAPTFWRVVRFLS--PLAL----------
--QGYVAWLRDMFLQPDLDSLVDFSTNNQKKAQDASL-----HVPERAVSRLRKWIIFRL
VSI-VDSLHLEMEEALTAQVARFCLFHAFFVTKKPTSQIPETKQPFSFPLESQAREAASS
AFFSLLQTLSTQ-------------LKQAPDQTRGGQPWTYHLVQFADLLLNHSH-NVTT
VTPF-SAQQRQAWDRMLQTLKELEAHSSEA-R--AAAFQHLLLLVGIHLLKS------PA
ESCDLLGDIQTCIRKSLGEKPR-RSRT---KAIDPQEPPWVEVLVEILLALLAQPSHLMR
QMARSVFGHICSHLTPRALQLILDVLNPETSEDE--DHVVVTDDSDERRLKGA-----ED
KSED-----GKDNRSSESEEESE--GEESEEEERDGD-VDQGFREQLMSVLQAGKALGGE
DSEDE----EELGDEAMMALDQSLASLFAEQKLRVQARRDEKNKLQKEKALRR-DFQIRV
LDLVEVLVTKQPENALVLELLEPLLSIIRRSLRSS----SSKQE---QDLLHKTARIFTH
HLCRARRYCHDLGERAEALHAQVERLVQQAGRQPDSPTALYHFNASLYLLRVLKGNTAEG
CVRETREKQKAAREGR---------------------------------------PGLS-
-Q--DPTLSQALVPSQGPLSCCLDLNLVTRVYSSALSSFLTKRNSPLTVPMFLSLFSRH-
------------------------------PLLCKSLLPILV-------QHVTGPVRPRH
Q--ACLLLQKTLSMREVRSC----FEDPEWKQLMGQVLAKVTEN----------------
--------------------------LRVLGEAQTKAEHQQALSSLELLNVLF---RTCK
QEKLTLDLTVLLGVLQGQQQ-------SLQQGAHS--TGSSRLHDL-----YWQAMKTLG
VQR-----------------------PKLEKKGAKE-VPSATQSPISKKRKKKGFLPETK
KRKKRKSEDGTLAE-----------DGTPAATGGSQP--PSMGRKKRKRT--KA------
------------------------------------------------------------
----------------------KVPAQ--ANGTPA-AKSPAPGTP---------------
----------------------------------------------------TLSPSTP-
AKSPELQKKNQKPSQVNGA-PRS---PVEPAGQKQPQKALPKKGVLGKSPR---SALARK
KAR--LSLVIRSPSLLQSGAKKKKAQ-LRK--AGKS---

Query Results

"ENSGT00390000017457_0"

ENSGT00390000017457_0