Query Results 

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---------MAALLRSARWLLRAGAAPRLPLSLRL-------LAGGAS--RLHAAPFLPA
ARAGPVAGGLLSQARLYAI-AVEKKNYLQEEPS-------SHRKNASQFDWALMRLDNSV
RRTGRIPKTLLQKVFDNTCH-SGSPGGNQALLLLRSCGSLLPELQLSERTEFAH

PF13812 // ENSGT00390000016775_0_Domain_5 (235, 295)

RIWDKL
QKLGTVYDVSHYNALLKVYLQNEYKFSPTDFLAKMEEANIQPNRVTYQRLIAAY

ENSGT00390000016775_0_Linker_5_7 (295, 310)

CNVGDI
EGASKILGF

PF17177 // ENSGT00390000016775_0_Domain_7 (310, 418)

MKTKDLPITEAVFSALVTGHARAGDIENAENILTV-MREAGIEPGPDTYLA
LLNAYAEKGDIDHVKQTLEKVKKSDLYLMDRDLLQIIFSFSKAGYSQYVPEILEKITYER
RYIPDAMNLILLLVTEKLEDTAFQILLACPVSRE-------DNLNDFGSFFLRHCVTMNT
PAEKLQDYCKQLKESQMHTSPLQFTLHCALQANKTDLAKALMKALKEEGF-PVRTHYFWP
LLAGHQKEKNVQGIIEVLKAMNEVGVNPDQETYINYVFPSFDSVRSVRGVLQENGCLPEN
N--VFSQAEFRSEAVTGN----LSYVLSFLESNTL-PFSFA-SLRGSLILGFR----RS-
------MDINL-WSKITELLYKDGRYCQEPPGPT-EAVGYFLYNLIDSMSDSEVQAKEER
LRQYFHQLKEMNVKIPENIYRGIRNLLDSYHVPELIKDVNMLVDREKIDSR----KTTQL
TSSVLESTLEKLKAENQPIGDVLKQLILVLCSEENMQKALELKAKYESD-MVVGG

PF01535 // ENSGT00390000016775_0_Domain_11 (836, 871)

YAALI
NLCCRHDNAEDALNL-------------KQ

ENSGT00390000016775_0_Linker_11_12 (871, 888)

EFDRLDPSAVLDTSKYV

PF01535 // ENSGT00390000016775_0_Domain_12 (888, 914)

GLVKVLGKHGKLQ
DAINILKEMKEKD

ENSGT00390000016775_0_Linker_12_13 (914, 1100)

VLIKDATVLSFFHILNGAALRGETETVKQLHKAIMTLGLAKPSTALS
SPLVTLYLEK-DDLSAALEVTIDC---YEKYKVLPRIHDVLCKLI-EKGETDLIQKAMNF
VSQEQGEMTMLYDLFFAFLQTGN-YKEAKKIIETPGIRARSSRLQWFCDRCISSNQVETL
EKLVE-LTQKLFECDRDQL

PF01535 // ENSGT00390000016775_0_Domain_13 (1100, 1128)

YYSLLKLYKINGDWQRADAVWNKMQEENIIPRAKTLRLLAE
ILRNNNQEVPFD----VPELWYEDEK-HSLS---S-SPPSREEANIQKDLLNACQRKKSK
-DAYSIFLKAHKQNIVLNNETYGSLIKLLLEKDSF-LQAMQVK-DVAETHIKGFTLNDAA
NSLLIITQVRRDYLKEALKTLKTALDLEQTPSRIAVTRLIQACALKGDVESIQEIQKMVN
GLEDSIGLSNMVFINNIALAQIKNNNIDVAIENIEN--MLTSGNETVKPQYFGLTYLFRK
VIEEQLEPAVEK----------------------------------------ISIMAERL
ANQFAVYKPVTDLFLQLLDSGKVDDARALLQRCGAIAEQTAIFLVFCVRSSRKPGKA---
-STLKSLLELIPELIEKEEAYTSIMKSYVLDKDAASAKALYENLTARNIKLNDLFLKRYA
VLLKNAGEPVPFTEPPESFEFYAKQLKESRGNPL----------

------------------------------------------------------------
---------MAALLRPARCFLRAGVAARLPLSLRL-------LAGGPG--WLHAAPGRLA
ARARPVAGKKVSQARLYAT-VAEKKDHFQEELT------SAHGRNATQFDWDLMRVDNSV
RRTGRITKTLLQKVFDSTCN-AGNPGSNQALLLLRSCGSLLPELKFSERTEFAHRIWDKL
QKLGTVYDISHYNALLKVYLQNEYKFSPTDFLAKMEEANIQPNR

PF01535 // ENSGT00390000016775_0_Domain_6 (285, 314)

VTYQRLIAAYCNMGDI
EGASKILGFMKNK

ENSGT00390000016775_0_Linker_6_8 (314, 321)

DLPITEA

PF01535 // ENSGT00390000016775_0_Domain_8 (321, 350)

VFSALVTGHARAGDMENAENILTV-MKEA

ENSGT00390000016775_0_Linker_8_7 (350, 357)

RIEPGPD

PF01535 // ENSGT00390000016775_0_Domain_7 (357, 384)

TYLA
LLNAYAEKGDIDHVKQTLEKVEKSDLYLTDRDLLQIIISFSKAGYPQYTSDILEKVTYQR
RYFPDLMNLILLLITEKLEDTAFQILLAYPVSRE-------DNLRNFGSFFLRHCVTMNT
PAEKLKDYCKKLKEAQMHTTPLQFTLCCALQNNKTDLAKALMKALKEEGF-PVRTHYFWP
LLVGHQKEKNVQGIIEVLKGMQEMGVNPDKETYVSYVFPSFDSVKSARAVLQENGCLTET
N--TFLQAELRSETVNGN----LDYILSFLESNTL-PLQFS-SLRGSLISGFK----RS-
------MNINL-WSKITELLYKDGRYCQEPPGPKTETVGYFLYNLIGSMSASEVQAKEKC
LRQYFHQLKDMNVKISQNIYKGIRNLLDSYHVPELIKDVNILLEDSQ--------KTLQQ
KSSDLEAKLNKLKAENQPIRDVLKQLIVALCSEENMEKALELKAKYESD-MVVSG

PF01535 // ENSGT00390000016775_0_Domain_11 (836, 872)

YAALI
KLCCRHGNAEDAWNL-------------KQE

ENSGT00390000016775_0_Linker_11_12 (872, 889)

LDRLDSSAVLDTSKYVD

PF01535 // ENSGT00390000016775_0_Domain_12 (889, 914)

LVKVLGRHGKLQ
DAVNILKEMKEKD

ENSGT00390000016775_0_Linker_12_13 (914, 1099)

VLIKDSTVSSFFHILNGAALRGEVETVKQLHEAILTLGLAKPSTNLS
SPLVTLYLEK-DDLPAALEVTLDC---HEKYKVLPRIHDVLCRLI-EKGKTELIQKAIDF
VSQEQGEMSMLYDLFFAFLQTGN-YKEAKKIIETPGIRARPTRLQWFCDKCISSNQVETL
EKLVE-LTQKLFECDRDQ

PF01535 // ENSGT00390000016775_0_Domain_13 (1099, 1128)

MYYNLLKLYKMNGDWQSADAVWNKMQEENIIPREKTLRLLAE
ILKNSNQEVPFD----VPELWYEDEK-QSLN---S-SSASSVESNFEKQLLNACRKKQSK
-VAYDIFLEAQSQNIKFTSGTYGSLIKLLLWKDNC-TEAMQVK-NVAETHIKGFTLNDAA
NSLLIIRQVRRDYLKEALTTLKTTLDLEQIPSRLAVTCLIQALALKGDVESIQMIQKMVN
GLEDSLELSSMVFINNIALAQIKNNNIDVAIEKIES--MLTSGNQAVNPQNFGLAYLFRK
VIEEQLEPALEK----------------------------------------LSIMAERL
ANHFAIYKPVTDLFLQLVNSGKVDDARALLQRCSAIAEQTPILVM-LLQSSKKPGKA---
-PTMKSLLELIPELIEKEDAHGAVMKSYALDNDVASAKALYEHLTAKKTKLNDLFLKRYA
VLLKNAGESVPFTEPPESFEFYAQQLKELKERPA----------

------------------------------------------------------------
----------AALLRPAGWLLRAGAAPRLPLSLRL-------LAGCSR--RPR-------
--AVPRAGVLLSQTRLYAI-AAEKKNVLQEEPP------FASRRNASQFDWALMRLDNSV
RRTGRIPKTLLQKVFESTCR-TXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXKILGFMKTKDLPVTE

PF01535 // ENSGT00390000016775_0_Domain_8 (320, 355)

AVFSALVTGHARAGDMENAENILTV-MKEAGIEPG

ENSGT00390000016775_0_Linker_8_7 (355, 356)

P

PF01535 // ENSGT00390000016775_0_Domain_7 (356, 390)

DTYLA
LLNAYAEKGDIDHVKQTLEKVEKSDLYLMDRDLLQVIFSFSKAGYPQYVSEILEKITYER
RYIPDAMNLILLLVTEKLEDTALQILLACPISKE-------DNLTNFGSFFLKHCVTMDM
PVEKLIDYCKKLKEAQMHTSPLQFTLHCALSAKKADLVMALMKALKEEGF-PVRTHYXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXAVLQENGYLPES
N--TFSEAELRSEAVNGN----LDYILSFLESNKS-PFPLS-SLRGSLILGFK----RS-
------MXXXX-XXXITELLYKDGRYCQEPPGPT-EAVGYFLYNLIDSMSDSEVQAKEER
LRQYFHQLKEMNVKIPENIYKGVRNLLDSYHVPELIKDVNLLVEREKIDPR----KTVQS
TSADLESTLERLKAQNQPAGDILKQLILVLCSEENMQKALELKEKYESD-MVI

PF01535 // ENSGT00390000016775_0_Domain_11 (834, 881)

GGYAALI
NLCCRHDNAEEALNL-------------KQEFDRLDSSAV

ENSGT00390000016775_0_Linker_11_12 (881, 884)

LDT

PF01535 // ENSGT00390000016775_0_Domain_12 (884, 918)

SKYVGLVKVLAKHGRLQ
DAINVLKEMKEKDVLIK

ENSGT00390000016775_0_Linker_12_13 (918, 1098)

DATVLSFFHILNGAALRGEIETVKQLHEAIVTLGLAKPSTNIS
APLVTVYLEK-GDLTAALEAAIDC---YVKYKILPRIHDVLCKLI-EKGETDLIQKXXXX
XXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXTPGIRARPTRLQWFCERCIASNQVETL
EKLVE-LTQKLFECDRD

PF01535 // ENSGT00390000016775_0_Domain_13 (1098, 1132)

QMYYSLLKLYKINGDWQKADAVWNKMQEENVIPREKTLQLLAQ
ILRNSNQEVPFD----VPELWYEEAA-DSLS---S-MPVSPTETNTEKDVLKACQIKKSK
-DAYNSFLKAQRLNIVFNNETYISLIKLLLSKDSF-TEAMQVK-DFAETHIKGFTLNDAA
NSLLITAQVRRDYLKDAVAVLKTALNQEQVPSRLAVTRLIQALALKGDVQSIEAIQKMVH
GLD-SIGLSNMVFINNIALAQIKNNKVDVAVENIEN--MLTSGTPTVEPQFFGLSYLFRK
VIEEQLDPAAEK----------------------------------------LSIMAERL
ANQFAVYKPVTDFFLQLVNTGKTEDARALLQRCSAIAEQTPVLLVFCIRTSQKPGKA---
-PVLKSLLELIPELIDKE

PF01535 // ENSGT00390000016775_0_Domain_20 (1519, 1553)

EAYTSVMKSYALDKDVASAKALYEHLTAQNVPLNDMFLKRYA
VLLKDAGEPVPFTEPPETFKFYANQLKESREKPS----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------NPSSNLALLLLRSCGSLLPELKPSERTEFVHRIWDKL
QQLXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXKILGFMKTKDLPVTEIVFSTLVTGHARNGXXXXXXXXXXX-XXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXTLEMMEKTDNYLMDRDLMQIVFSFSKAGYPQYVSEILERMKFER
RYIPDVMNLCLSLVTERLEDVAMQILVSCPKSLLENTQENASNLNNFGNFFLQHCVTMNT
P-NKLEEFCEKLKEEKLHVAPLQFTLYCAVKAKKTALATDLMKAMKEQKT-PIRPHYFWP
LLTGHQD-KNIQGIIEIVKRMHELGVNPDAETYGNYVFPAFDNIKSARTVLQENGCPVND
D--ILFLAELRNEAINGN----LERVLSLLVSSTS-SIDLS-SFRGSLVLGFR----XX-
------XXXXX-XXXITEQLYTDGHYCQAPPGPTXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXX-----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXILVE
NSSDLEQKLENLKTENRPIGDTLKQLILILCSEENMQKALEIKTKYESD-MVVGGYAALI
SLCCRHDNVEDAMNL-------------KQQVXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XAINILKEIKEKDVLLKDRT--AFFHILNEAAFLGEVETVKQLHEAIMTLGLAKPSITLC
SPLVTLHLEX-XXXXXXXXXXXXX---XXXXXXXXXXXXXXXXXX-XXXXXXXXXXXMDF
VSQEQGEMTMLYDLFFAFMQTGN-YKEAKKIIEXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXX-XXXXXXXXXXXXXXXXXXXXXXENNDWQRADAIWTKIQEENIIPRQKTLKLLGE
ILRNNNQDVPFD----IPMLWYDNLK-LILN-----TADLPPEAVLKKELMTACQRKKSE
-DAYAIFLEAQKKNVVFSALVYSTVIKLLLASGSL-DEALNVK-NIAETHIKGFTLNDAA
NSLLIITQVRRDYLKDALTTLTTALESHQVPSPLSVTRLVQAFALKGDKENIQVIEKMVH
DLQDPIRLSRMLFINNNALAEIKNNNLDAAVEYLES--LFTSGPLGTDKQQSSIAYLFRK
VIEEQLEPATEK----------------------------------------LSIMAERL
ANQFAIYRPVTDLFLEYLHSGRVDDARALLQRCGAIAEQTPVLLGFLLKNSKIQGQT---
-HVLKSLLEMIPDITANL

PF01535 // ENSGT00390000016775_0_Domain_20 (1519, 1553)

EVYGFLMRSFGLDSDVASANALYEEMKAKSIKMDNIFLKQYA
ALLKNAGEPVPFTEPPESFKFYIEQSKKEVQAPS----------

------------------------------------------------------------
---------MAALLRPARWLLRARAAKSLPLSLRL-------LAGGPG--RPHAAFCLPT
GRARPVAGGLQSQVRLYTI-AAEKKNYLQEEPA------SSHKRNASQFDWALMRLDNSV
RRTGRIPKTLLQKVFDNTCH-SGSPGSNQALLLLRSCGSLLPELKLSERMEFAH

PF13812 // ENSGT00390000016775_0_Domain_5 (235, 296)

RIWDEL
QKLGTVYDISHYNALLKVYLQNEYKFSPTDFLAKMEKANIQPNRVTYQRLIAAYC

ENSGT00390000016775_0_Linker_5_7 (296, 308)

NEGDI
EGASKIL

PF17177 // ENSGT00390000016775_0_Domain_7 (308, 418)

GFMKTKDLPITEAVFSALVTGHARAGDMENAENILTV-MKEAGIEPGPDTYLA
LLNAYAEKGDIDHVKQTLEKVEKSDHFLMDRDLLQIIFSFSKAGYPQYVSEILEKITYER
RYIPDTMNLILLLVTEKLEDTALQILLACPVSRE-------DSLSDFGSFFLRHCVTMNT
PTEKLKDYCKKLKEARLHRSPFQFTLQCALLANKIDLAKSLMKALKEEGF-PIRTHYFWP
LLVGYQKEKNVQGIVEILKGMHELGVTPDQETYINYVFPCFDSIKSVRAVLQEHGCLHEN
T--VFSQAELRSEAVNGN----LDYILSFLESNTL-PLSFT-SLRGSLILGFR----RS-
------MDINL-WSKITELLYKDGRYCQEPPGPT-EAVGYFLYNLIDSMSDSEVQAKEER
LRQYFHQLKEMNVKIPENIYKGIRNLLDSYHVPELIKDVNKLVEREK--TDPQKT--AQL
TLSDLESKLEKLKSENQPIGDVLKHLILILCSEENMEKALELKAKYESD-MVVGG

PF01535 // ENSGT00390000016775_0_Domain_11 (836, 871)

YAALI
NLCCRHDNAEDALNL-------------KR

ENSGT00390000016775_0_Linker_11_12 (871, 888)

EFDRLDSSAVLDTGKYL

PF01535 // ENSGT00390000016775_0_Domain_12 (888, 914)

GLVKVLGKHGKLQ
DAINILKEMKEKD

ENSGT00390000016775_0_Linker_12_13 (914, 1100)

VLIKDATVLSFFHILNGAALRGETETVKQLHEAIVTLGLAKPSSSLS
SPLVTLYLEK-DDLPTALEVTIDC---YEKYKVLPRIHDVLCRLI-EKGKTELIQKAMDF
VSQEQGEMTMLYDLFFAFLQTGN-YKEAKKIIETPGIRARPTRLQWFCDRCIASNQVETL
EKLVE-LTQKLFECDRDQL

PF01535 // ENSGT00390000016775_0_Domain_13 (1100, 1128)

YYNLLKLYKVNGDWQRADAVWNKMQEENIIPRGKTLRLLAE
ILRNSNQEVPFD----VPELWYEDEQ-HSQI-----SSASPEQGNLQKELLKACRKRKNR
-DAFNIFLKAKRQNIVFDDETYNTLIHFLLSKDNS-VEAMQVK-DFAETHIKGFTLNDAA
NSLLIITQVRRDYLKDALTTLKTALDLEQIPSRIAVTRLIQAYAMKGDTESIRAIQKLVN
GLEDSIGLSRMVFINNIALAQIKNNDIDVAVENIEN--MLTSENPTMEPQYFGLAYLFRK
VIEEQLEPALEK----------------------------------------ISIMAERL
ANQFAVYKPVTDLFLQLVDSGKVDDARALLQRCGAIAEQIPIFLVFCIRNSQRSGKA---
-STMKSLLELIPELIDKEEAYTSIMKSYVLDKDVTSAKELYENLTAKDTKLNDLFLKRYA
VLLKNAGESVPFTEPPESFEFYAKQLKESKENPL----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------MHSVDLF-HFKGCLISGFR----RS-
------KNVDL-WSKITELLYKDGRYCQTPPGPS-EAVGYFLYNLIDSMSDSEVQAKEEH
LRQYFHQLKKMNIVIPPNIYRGIRNVLDSYHVPELIKDIMLVVDS-EKLSAADIPKNTEL
EVLSLEEELEKLKAEKQPIGNVLKQLIVALCAEENMQKALEVKAKYEPD-MVVGG

PF01535 // ENSGT00390000016775_0_Domain_11 (836, 871)

YAALI
NLCCRHDNAEDAMNL-------------KE

ENSGT00390000016775_0_Linker_11_12 (871, 886)

EVYRKDSSVALDTNK

PF01535 // ENSGT00390000016775_0_Domain_12 (886, 914)

YLALVKVLGKHGRLE
DAINILKEMKEKDVPIRDTTVTSFFHILNAAAMQGEVETVNRLHESILTLGLVKPSTNLC
SPLITVHLEKRDDVPAALEAAIDC---FKKYGNIPRLHDILCRLI-EKGNTDLLQKAMDF
VSQERGEMTMLYDLFFAFLNTGK-YKEAKKIIETPGLRARPGRLQWFAEKCIANNQMDIL
ENMVE-MTEKLFECDRDQMYYYILQLCKISSDWRRADATWTKMQEENVIPRERTLRLLAD
ILKNNGQEVPFD----VPEIWYEDCVESAPV---------SE-NNPEKKILILCKKGNIQ
-EAYNILLEEQKKDIMFPS

PF01535 // ENSGT00390000016775_0_Domain_16 (1220, 1242)

FTYSILIKALLAEGCL-EKAINVK-NIAETHIKGFTLNDAA
SSLLIITQVRRDYLKDAISTLKAVLENDMVPTRLAVTRLIQALAMKGDVESVRTVEKMVE
NLAVSIGLSRMLFVNNTVLAHIKNNNLDTAVEYIES--LIISGMQNPDSPITSISYVFRK
VIEEKLESALEK----------------------------------------LSAMAERL
VNQFGIYKPATDLFLQYVSEGRIDDARLLLQRCGGIAEQKKIMMAFIAKSSQKPGQG---
-QKIKMLLDLVPDFPEMEVVYSYLLKCHVLDNDIVSAKTLFEKAKAENIRTDEIFLKRLA
FLLKSAGEPVPFTEPPESFHFYVNKLRKERQELSSHDGQV----

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------MSDSEVQAKEEH
FRQYFHQLEKMNVKIPENIYRGIRNLLDSYHVPELIKDAHLLVDSKNLDFQ----KTVQH
TSSVLESTLETLKAENQPIRDVIKQLILVLCSEENMQKALELKAKYESD-MVTGG

PF01535 // ENSGT00390000016775_0_Domain_11 (836, 871)

YAALI
NLCCRHDNVEDALNL-------------KE

ENSGT00390000016775_0_Linker_11_12 (871, 888)

EFDRLDSSAVLDTGKYV

PF01535 // ENSGT00390000016775_0_Domain_12 (888, 914)

GLVRVLAKHGKLQ
DAINILKEMKEKDVLIKDTTALSFFHMLNDAALRGETETVKQLHEAIVTLGLADPSTNIS
FPLVTVHLEK-GDISTALEVAIDC---YEKYKVLPRIHDVLCKLV-EKGETDLIQKAMDF
VSQEKGEMLMLYDLFFAFLQTGN-YKEAKKIIETPGIRARSARLQWFCDRCVANNQVETL
EKLVE-LTQKLFECDRDQMYYNLLKLYKINGDWQRADVVWNKIQEENVIPREKTLRLLAE
ILREGNQEVPFD----VPELWYEDEK-HSLNS----SSASTTEPDFQKDTLNACRLKQKE
-GAYNIFLNAKEQNIVFNAETYSNLIKLLMSEDYF-TEAMEVK-AFAETHIKGFTLNDAA
NSRLIITQVRRDYLKEAVTTLKTVLDQQQTPSRLAVTRIIQALAMKGDVENIELVQKMLN
GLEDSIGLSKMLFINNIALAQIKNNNIDVAIENIEN--MLTSENQVIGPQYFGLAYLFRK
VIEEQLEPAVEK----------------------------------------ISIMAERL
ANQFAIYKPVTDFFLQLVDAGKVDDARALLQRCGAIAEQTPILLLFLLRKSEKRGKA---
-STVKSVLELIPELNEKEEAYSSLMKSYVSEKDVTSAKALYEHLTAKNTKLNDLFLKLYA
SLLKNAGEPVPFIEPPESCEFYAQQLRKLKENSS----------

------------------------------------------------------------
---------MAALLRPAGWLLSAGAAPRLPLSLRL-------LAGAPG--WPHAALCHPS
ARAGPVAGGPLSQARLYAI-AAERKNYLQEEST-------SQRRNASQFDWALTRLDNSV
RRTGRIPKTLLQKVFDNTCD-SGCPGGNQALLLLRSCGSLLPELKVSERTELAHRIWDKL
QKLGTAYDI

PF01535 // ENSGT00390000016775_0_Domain_5 (250, 284)

SHYNALLKVYLQNEYKFSPTDFLAKMEEANIQPNRVTYQRLIAAYCNMGDI
EGASKILGFMKTKDLPVTE

PF01535 // ENSGT00390000016775_0_Domain_8 (320, 355)

AVFSALVTGHARSGDMENAENILTV-MKEAGIEPG

ENSGT00390000016775_0_Linker_8_7 (355, 356)

P

PF01535 // ENSGT00390000016775_0_Domain_7 (356, 390)

DTYLA
LLNAYAEKGDIDHVKQTLEKVEKSDLYLMDRDLLQIIFSFSKAGYPQYVSEILEKIAYER
RYIPDAMNLILLLVTEKLEDTALQVLLACPISRE-------DGLSDFGSFFLRHCVTMNT
PEEKLKDYCKKLKEAQMHTAPLQFTLQCALVANKADLAKALMKALKEEGF-PVRT

PF01535 // ENSGT00390000016775_0_Domain_10 (536, 570)

HYFWP
LLVGHQKKKNVQGIVEVLKGMHEMGVNPD

ENSGT00390000016775_0_Linker_10_11 (570, 834)

QETYVNYVFPSFDSITSVRAILQXXXXXXXX
X--XXXXXXXXXXXXXXX----XXXXXXXXESNTL-PFSLT-TLRGSLILGFR----RS-
------MNVNL-WSKITELLYKDGRYCQEPPGPT-EAVGYFLYNLIDSMSDSEVQAKEER
LRQYFHQLKEMXXXXXXXXXXXXXXXXXXXXXXXXXXDVSILVEREKTDSR----KTTQL
TSSDLESTLEKLKAENQPIGDVLKQLILTLCSEENMKKALELKAKYEPD-MAV

PF01535 // ENSGT00390000016775_0_Domain_11 (834, 881)

GGYAALI
NLCCRHDNAEDALNL-------------KQEFDRLDSSAV

ENSGT00390000016775_0_Linker_11_12 (881, 884)

LDT

PF01535 // ENSGT00390000016775_0_Domain_12 (884, 918)

NKYVRLVKVLGKHGKLQ
DAINILKEMKEKDVLIK

ENSGT00390000016775_0_Linker_12_13 (918, 1098)

DATVLSFFHILNGAALRGETETVKQLHEAIVTLGLTKPSTTIS
SPLVTLYLEK-DDLPAALEASIGC---YEKYKILPRIHDVLCKLI-EKGETDLIQKAMDF
VSQEQGEMTMLYDLFFAFLQTGN-YKEAKKIIETPGIRARPARLQWFCDRCISSNQVETL
EKLVE-LTQKMFECDRD

PF01535 // ENSGT00390000016775_0_Domain_13 (1098, 1132)

QLYYNLLTLYKVNGDWQRADAVWNKMQEENIIPRGKTLRLLAE
ILRNNNQEVPFD----VPELWIEEEK-HSLN---S-SAPSHVETNIEKDLLRACQWKKSR
-DAYDTFLKAQKQNVVFNSETYSSLIKLLLTKDSF-PQAMQVK-DFAETHIKGFTLNDAA
NSLLIITQVRRDYLKEALTTLKTALDLKQTPSRVAVTRLIQACALKGDTESIHAIQKMVN
GLKDSIGLSHMVFINNIALAQIKNNNIDVAIENIEN--MLTSGNQTVEPQYFGLAYLFRK
VIEEQLEPALEK----------------------------------------ISIMAERL
ANQFAVYKPVTDLFLQLLDSGKVDDARALLQRCGAIAEQTPIFLVFCIRSSRRPGKA---
-PTLKSLLELIPELTEKE

PF01535 // ENSGT00390000016775_0_Domain_20 (1519, 1553)

EAYNSVMKSYVMDSDVPSAKALYENLTAKNIKLDDLFLKRYA
VLLKNAGESVPFTEPPESFEFYAKQLKELRENPL----------

------------------------------------------------------------
---------MAALLRSSCWLLRAGAAPRLPLSLRL------LTGG-PG--RPHAASYLPA
ARAGPVAGGLLSPARLYVI-AAEKKDI-QEES------TFSSRRIASHFDWALMRLDNSV
RRTGRIPKMLLQKVFDDTCRS-GGPGSSHALLLLRSCGSLLPELKLEERTEFAH

PF13812 // ENSGT00390000016775_0_Domain_5 (235, 294)

RIWDKL
QKLGAVYDVSHYNALLKVYLQNEYKFSPTDFLAKMEEANIQPNRVTYQRLIAS

ENSGT00390000016775_0_Linker_5_7 (294, 309)

YCNTGDI
EGASKILG

PF17177 // ENSGT00390000016775_0_Domain_7 (309, 417)

FMKTKDLPVTEAVFSALVTGHARAGDMQNAENILTV-MREAGIEPGPDTYLA
LLNAYAEKGDIDHVKQTLEKVEKSELHLMDRDLFQIIFSFSKAGYPQYVSEILEKVTCER
RYIPDAMNLILLLVTEKLEDVALQILLACPISKE-------DGISDFGGFFLRHCVTMNT
PVEKLTDYCKKLKEIQMHSFPLQFTLHCALLAKKTDLAKALMKAVKEEGF-PIRTHYFWP
LLVGHQKEKNVQGIIEVLKVMQELGVPPDQETYIGYVIPCFNSIKSARAILQENGCLSNS
D--TFSQAELRSEAVNGN----LDFVLSFLESNTL-PLSLQ-SIRSSLLLGFR----RS-
------MNINL-WSKITELLYKDGRYCQEPPGPT-EAVGYFLYNLIDSMSDSEVQAKEER
LRQYFHQLKEMNVKIPENICRGIRNLLDSYHVPELIKDAYMLVDSENLDSQ----KTVQL
RSSELESRLETLKAEDKPIRDVLKHLILALCSQENMQKALELKAKYESD-MVIGG

PF01535 // ENSGT00390000016775_0_Domain_11 (836, 871)

YAALI
NLCCRHDNAEDALSL-------------KE

ENSGT00390000016775_0_Linker_11_12 (871, 888)

EFDRLDSSAVLDTSKYV

PF01535 // ENSGT00390000016775_0_Domain_12 (888, 914)

GLVRVLAKHGRLQ
DAINILKEMKKKDVPIKDSTVLSFFHILNGAALRGEIETVKQLHEAIVTLGLAKPSTNIS
FPLITVYLEK-DDLSTALDVAIDC---CEKYKILPRMHDILCKLI-EKGETDLIQKAMDF
VSQEQGEMVMLYDLFFAFLQTGN-YKEAKKIIETPGIRARSTRLQWFCDKCIANNQVETL
EKLVE-LTQKLFECDRDQMYYNLLKLYKMNGDWQRADAVWNKIQEENIVPREKTLRLLAE
ILRDGNQEVPFE----VPE-WYEDEK-HSLNSSLDSSSDSTTEPGLQKDILNACQLKQSK
-EAYGIFLKAKQQNVVFNAETYSDLIKLLLSKEYF-TQAVEVK-AFAETHIKGFTLNDAA
NSLLIITQVRRDYLKEALTTLKTALDQQQTPSGTAVTRLIQALAMKGDVENIEVVQKMVN
GLEDSIGLSKMVFINNTALAQIKNNNIDVAIENIEN--MLTSENPVIELQYFGLAYLFRK
VIEEQLEPAVEK----------------------------------------ISIMAERL
ANQFAIYKPVTDFFLQLVDAGKVDDARALLQRCGAIAEQTSILLVFFLRNAGKQGKA---
-STLKSLLELIPELNEKEEAYSSLMKSYVSEKDVTSAKALYEHLTAKNTKLDDLFLKRYA
FLLKNAGESVPFTEPPESFEFYVQQLKELRENSS----------

------------------------------------------------------------
------------------------------------------------------------
-------------ARFLTV-VPQHEGSFKEEAVSE-----IQSRRA--FDWALNKLDNSV
RKTGRIPKTLLLKVFQETCRE-GCPGSNQTLLLL

PF01535 // ENSGT00390000016775_0_Domain_0 (215, 249)

RSCGALLPEVLSSERTELVHMIWDKM
KELGAVYD

ENSGT00390000016775_0_Linker_0_5 (249, 250)

T

PF01535 // ENSGT00390000016775_0_Domain_5 (250, 284)

SHYNALLKVYLQNEHKFSPTEFLARMEEANVQPNRVTYQRLIAAYCNEGDI
EGASKILGFMKSKDLPITE

PF01535 // ENSGT00390000016775_0_Domain_8 (320, 355)

AVFSSLVKGHARSGDIKSAENILSV-MRVAGVEPG

ENSGT00390000016775_0_Linker_8_7 (355, 356)

P

PF01535 // ENSGT00390000016775_0_Domain_7 (356, 390)

DTYLS
LLNVYAEKGDADSIKKTLEEVEKTGGYLMDRVLMQVIFSLAKAGYPQYIEDIKERIRFEK
ELIPDMMNLCLTLITHGFEDISFRILKSYNHLSR--------ENVDQGSFFLQHCVNRNM
PISKLKQFCYELKEAKMHSSPLIFILRCALETNKSDLAIDVMKAMKEEGL-PIRP

PF01535 // ENSGT00390000016775_0_Domain_10 (536, 570)

HYCWP
LLVGFQKEKNLKGVFEVLKVMHELGVELN

ENSGT00390000016775_0_Linker_10_11 (570, 834)

AETYTDYVFKNFADIETACAQMKENNCLFET
V--GFLVAKIRHEAGHGR----LKNVVSLLSSASTPSIDFR-QFRNSLILGFR----SS-
------NDVQL-WSKITELLYKDERYCLTPPGPT-EAVGYFLYHLIDSMSDSEVQAKEER
LRQYFHQLKKMNIVIPATYCSGICRLLDSSQVPELIKDVRLLSPK-KSMSSEDITDSAKS
DVSALEKKLEKRKAENQPITDVLKQLIYALCEEENMQKALEVKAKYEPD-MVV

PF01535 // ENSGT00390000016775_0_Domain_11 (834, 881)

GGYAALI
NLCCRHDNLEEAMNL-------------KEKVFPKSSPVA

ENSGT00390000016775_0_Linker_11_12 (881, 884)

LDS

PF01535 // ENSGT00390000016775_0_Domain_12 (884, 918)

GKYIALVEALAKHGRLE
DAISILTEMKEKDVPIS

ENSGT00390000016775_0_Linker_12_13 (918, 1098)

DRAVASFFRLLNAAAIRGEVETVNRLHETIVNLGLAE-TAALY
SPLITVHLEK-DDMPAALEALMDC---YKKHGKILQLHNIYCRLI-EKGDTELLQKVSDF
ISSEYGDMMALYDLFFAFLQTGK-YKEARKVIETPGLRAHSGRLQWFAKRCITGNQMETL
EHLVE-LTQNVFECDRD

PF01535 // ENSGT00390000016775_0_Domain_13 (1098, 1132)

EMYYYLLQLCDNNSDWRRAEAVWTKIQEENVVPREKTLRLLAD
ILEKNGQVVPFE----VPKVMT---TQEETRSLGSSNFEKNIYRYFHETDIILCRLCKKK
-KAYNVFLKSQGKSD-YQYRTYDILIKALLSLDCI-EEAKRVK-HIAETHIKGFTLNS

PF01535 // ENSGT00390000016775_0_Domain_18 (1259, 1293)

AA
SSLLIISQVRRDYLKDAVAAFQGMLDSGLLPS

ENSGT00390000016775_0_Linker_18_20 (1293, 1519)

RPAVIALTQALAMKGDLRNLKALENMVE
SITKSIGLSSSLISNAIALAHTQNNDLDAAVEYLEP--LLISGAQDPDQPVKNISFLLRK
VSEKGLEPALEK----------------------------------------FGVMAERL
ANQFGIYRPVTDLFLQYVSADRVDDARSLLQRCGGLVEEKRTFVNYMIKSATKPGQA---
-RKIETLLELIPDNVDLE

PF01535 // ENSGT00390000016775_0_Domain_20 (1519, 1553)

TAYRHLLRCYELDGDVASVKAVYEKTKEKNIQLPELSLKSLA
AFLKKAGEPVPFTEPPESFKFYVEEWRKRRLEAS----------

------------------------------------------------------------
---------MAALLRPARWLIRAGTTRRLPLSLRL-------LAGGTG--RPHPVPCLAG
ARAGLPAGELVSQARQYAI-AAEKKNYLQEES------VSAQGRNASQFDWALMRLDSSV
RRTGCISKTLLQKVFNNTCHS-GSPSGSQALLLLRSCGSLLPELKLSERTEFLHQIWDKL
QKLGTVYDVSHYNALLKVYLQNEYQFSPTDFLAKMEEANIQPNR

PF01535 // ENSGT00390000016775_0_Domain_6 (285, 319)

VTYQRLIAAYCNVGDI
EGASKILGYMKSKDLPIT

ENSGT00390000016775_0_Linker_6_8 (319, 320)

E

PF01535 // ENSGT00390000016775_0_Domain_8 (320, 355)

AVFSALVTGHARAGDMENAENILTV-MKEAGIDPG

ENSGT00390000016775_0_Linker_8_7 (355, 356)

P

PF01535 // ENSGT00390000016775_0_Domain_7 (356, 390)

ETYLA
LLNAYAEKGDIDHVKQTLEKVEKSDLYLMDRDLLQIIFTFSKAGYPQYSSEILEKITYER
RYIPDAMNLILRLVTEKLEDTALQILLACPVSRE-------DNLSDFGSFFLRHCVAMDT
PVEKLKDYCKKLKEEQMHSSPLQFTLHCALSTRKADLAKALMKALKEEGF-PVRT

PF01535 // ENSGT00390000016775_0_Domain_10 (536, 570)

HYFWP
LIVGHQKEKNVQGIIEVLKGMHETGVSPDQETYINYVFPSFDSIKSARAVLEENGCLLER
S--VILHAELRSEAVSGN----LDSVVSFXXXXXX-XXXXX-XXX-------X----XXX
XXXXXCKNINL-WSKITELLYKGGRYCQEPPAQT-XXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----XXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNMQKALDIKAKYESD-MVVGGYAALI
SLCCRHDNAEDALNL-------------KQEXXXXXXXXXXXXXXXXXXXXXXXXXG--K
LAINILKEMKEKDVDVKDATVLSFFHLLNGAALRGEEETVSQLHEAIVTLGLAKPSSTLS
SPLVTVYLQK-GDFAAALKASIDC---YEKYKILPRIHDVLCKLI-EKGETELIQKAMDF
VSQEXXXXXXXXXXXXXXX-XXXXXXXXXXXXXTPGIRARPTRLQWFCERCXXXXXXXXX
XXXXX-XXXXXXXXXXXXXXXXXXXXXXINGDWQRADV-VNKMQEENVIPREKTLRLXXX
XXXXXXXXXXXX----XXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXX--X--XXXXX
-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXX-XXAETHIKGFTLNDAA
NSLLIITQVRRDYLKEALQVLTVALEQAQVPTRLAVTRLIQAFGSKGDVESVQTVQKMVK
GLEDFIGLSHMVFINNIALAQIKXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXX----------------------------------------XSIMAERL
ANQFAVYKPVTDLFLQLVDSGRVEDARALLQRCSAIAEQTPILSVYCVRSSQSPGKT---
-PTMKSLIELIPELIEKE

PF01535 // ENSGT00390000016775_0_Domain_20 (1519, 1553)

EAYTSIMKIYALDGDVASAKALYEHLSTKNVNLHDLFLKRYA
VLLKSTGESVHFTEPT----------------------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------QFDWALNKVDNSV
RKTGRIPKALLLKILQEISK-AGCPGSNHTLLLLQSCGAVLPEVLSPERTELAHMIWDKM
KELGAVYDTSHYNALLKVYLQNEHKFSPTEFLARMEEANVQPNR

PF01535 // ENSGT00390000016775_0_Domain_6 (285, 314)

VTYQRLIAAYCNEGDI
EGASKILGFMKSK

ENSGT00390000016775_0_Linker_6_8 (314, 321)

DLPITEA

PF01535 // ENSGT00390000016775_0_Domain_8 (321, 351)

VFSSLVKGHARSGDMKSAENILSV-MRMAGVEPGPDTYLS
LLNVYAEKGDADSIKKTLEQVENTEGYLMDRILVQVIFSLAKAGYPQHIEDIKGRIRFER
ELIPDVINLCLTLITHGFEDISFNILKSLSHLSR--------EDMDQGSFFLQHCVNRDL
PVNKLKQFCKELKEAKMHSAPLPFILRCALEANRPALAIAVMKMMKEEGL-PLRPHYCWP
LLVAYQKENNLKGIFEVLKVMNKLGVDLDAETYTNYVFKNFADIETAHAQLKENGCLFQS
V--GLYVAELRSEASQGR----LDKVLSIMSSANTPAIDYR-LFRNSLIFGFK----SS-
------IPSLVGDTFITELLYNDERYCLTPPGPT-EAVGYFLYHLIDSMSDSEVQAKEER
LRQYFHQLKEMNIVIPTSHYSGICRLLDSSQVPELIKDVRLLLIR-QVVQ-G---RVAKS
DVSALEKKLEQRKAENQPITDVLKQLIHALCEEENMQKALEVKAKYEPD-MVVGG

PF01535 // ENSGT00390000016775_0_Domain_11 (836, 855)

YAALI
NLCCRHDNVEEAMN

ENSGT00390000016775_0_Linker_11_12 (855, 886)

L-------------KEKVFPKNSPVALDSGK

PF01535 // ENSGT00390000016775_0_Domain_12 (886, 914)

YVALVEVLEKHGRLE
DAINILTEMKEKDVPISGRAVASFLRILNAAAKRGEVETVNRLHDAIANLGLVQ-TAALH
APLITVHLEK-DDMPAALEAFISC---YKKYGKILQLHNICCKLV-EKGDADLLQKVSDF
ISREYGDMMALYDLFFAFLQTGK-YKEAKKVIETPGLRAHSGRLQWFAKKCILNQQMETL
EQLVE-STRNLFECDRDEMYYHLLKLCESNKDWGKAEAVWTKIQEENIVPRERTLTLLAD
IFEKNGQVVPFE----VPKVSGDRP--EDSRSDASG--EELK-------

PF01535 // ENSGT00390000016775_0_Domain_14 (1190, 1213)

IQMLCKKNKAK
-DAYNIFKRMQERDE-SHYRSCEILIKALLTQNCL-DEALDVK-RIAETHIKGFTLNSAA
SSLLIISQVRRDYLKDALAVLKGMLDSGMLPTRPAVVALIHALAEKGDVKNLEALENILG
DVTKSIHLSASLMPNAIALAHTKSNDLDAAVKYLEP--LLISGAQNPDQAVKSISYLLRV
VSEEGFEPALEK----------------------------------------FGAMAERL
ASQCGIYRPVTDLFLQYISAGRVDDARSLIQQCMPES------GAFIFQNCCTASRTLRT
AVKLSGVASVSSQCFSRKRLSSSRWLSMKLDGDVASVKATYEKAKAKNIELHEITLKSLA
TFLKKVGEPVPFTEPPESLKFYVEKWRNRRSEAS----------

------------------------------------------------------------
---------MAALLRPARWLLRAGAAPHLPLSLRL-------LAGGPR--RPHAAFCPHA
ARAGRVAGALLSQARLYTI-AAEKKNYLQEEAT------SSHRRNTSQFDWALMRLDNSV
RRTGRIPKTLLQKVFDNTCH-SGSRGGNQALLLLRSCGSLLPELKLSERTEFAHRIWDKL
QKLGTVYDVSHYNALLKVYLQNEYKFSPTDFLEKMEKANIQPNR

PF01535 // ENSGT00390000016775_0_Domain_6 (285, 319)

VTYQRLIAAYCNMGDI
EGASKILGFMKTKDLPVT

ENSGT00390000016775_0_Linker_6_8 (319, 320)

E

PF01535 // ENSGT00390000016775_0_Domain_8 (320, 355)

AVFSALVTGHARAGDMENAENILTV-MKEAGIEPG

ENSGT00390000016775_0_Linker_8_7 (355, 356)

P

PF01535 // ENSGT00390000016775_0_Domain_7 (356, 390)

DTYLA
LLNAYAEKGDIDHVKQTLEKVEKSDLYLMDRDILQIIFSFSKAGYPQYVSEILEKITYER
RYIPDTMNLILLLVTEKLEDTALQILLACPISRE-------DSLSDFGSFFLRHCVTMNT
PAEKLKDYCKKLKEAQMHTSPFQFTLHCALLAKKMDLAKALMKALKEEGF-PIRTHYFWP
LLVGHQKEKNVQXXXXXXXXXXXXXXXXXXXXXXXXXXPCFDSVKSARA-IQENGCLHED
S--IFSQAELRIEAVNGN----LDYILSFLESNTL-PLSFA-SLRGSLILGFR----RS-
------MNINL-WSKITKLLYKDGRYCQEPPGPT-EAVGYFLYNLIDSMSDSEVQAKEEH
LRQYFHQLMEMNVKIPENIYRGIRNLLDSYHVPELIKDVNMLVEREKTDSR----KTTQP
TSSDLESKLEKLKAENQPIGDVLKQLILMLCSEENMHKALELKAKYESD-MVI

PF01535 // ENSGT00390000016775_0_Domain_11 (834, 881)

GGYASLI
NLCCRHDNAEEALNL-------------KREFDRLDSSAV

ENSGT00390000016775_0_Linker_11_12 (881, 884)

LDT

PF01535 // ENSGT00390000016775_0_Domain_12 (884, 918)

SKYVRLVKVLGKHGKLQ
DAINILKEMKEKDVLIK

ENSGT00390000016775_0_Linker_12_13 (918, 1098)

DATVLSFFHILNGAALRGETETVKQLHEAIVTLGLAKPSTTLS
SPLVTLYLEK-DDLPTALEVTIDC---YKKYKILPRIHDVLCKLI-EKGETDLIQKAMDF
VSQEQGEMTMLYDLFFAFLQTGN-YKEAKKIIETPGIRARPTRLQWFCDRCIASNQVETL
EKLVE-LTQKLFECDRD

PF01535 // ENSGT00390000016775_0_Domain_13 (1098, 1132)

QLYYSLLKLYKVNGDWQRADAVWNKMQEENIIPRGRTLRLLAE
ILRNSNQEVPFD----VPELWYEDEK-HSLT-----SSPSPVEVSLQKELLNACHRKKDK
-DAFNIFLKAKKQNVVFNSETYASLINLLLMKDNP-TQAVQVK-DFAETHIKGFTLNDAA
NSRLIITQVRRDYLKDALTTLKTALDLEQIPSRIAVTRLIQACALKGDTESIQDIQKLVN
GLEDSIGLSRMVFINNIALAQIKXXXXXXXXXXXXX--XXXXXXXXXXXXXFGLAYLFRK
VIEERLEPALEK----------------------------------------ISIMAERL
ANQFAIYKPVTDLFLQLVDAGKVDDARALLQRCGAIAEQTPIFLVYCIRNSRRSGKA---
-PTVKSLLELIPELTEKE

PF01535 // ENSGT00390000016775_0_Domain_20 (1519, 1553)

EAYTSIMKSYVLDSDVASAKALYENLTAKDVKLNDLFLKRYA
VLLKNAGESVPFTEPPESFEFYAKQLKESKENPL----------

------------------------------------------------------------
---------MASLLRPARWLLRAGLSPRLPLSLRL-------LAGGPG--RPHVASCLPA
ARARPLAREPLNQTRLYAI-VAEKKDDLLEENT------S-SRRNSGQFDWALMTLDNSV
RRTGRITKWLLQNVFESTCR-SGNPGSNQALLLLRSCGSLLPEISLTERTDFAHKIWDKL
QELGTVYDVSHYNALLKVYLQNKYKFSPTDFLAKMEAANIQPNRVTYQRLIAAYCNVGDI
EGASK

PF17177 // ENSGT00390000016775_0_Domain_7 (306, 418)

ILEFMKTKDLPVTEAVFSALVTGHAKAGDIENAENILTV-MREAGIEPGPDTYLA
LLNAYAEKGDIDHVKQTLEKAQKSDLYLTDRDLLQLIFSFSKAGYPQYVSEILEKLTCEK
RYIPDAINLILLLVTEKLEDTALKVLLTCSVSRE-------DTQNDFGRFFLRHCVTMNT
PAEKLTDYCKKLKEAQMHSSPLKFTLYCALQANKTGLATALIKALKEEGF-PVRTHYFWP
LLVGHRKEKNVQGIIDILKEMREVGVEPDPETYVNYVFPSFDSVTSVRALLQENKCLPER
D--WLGVAEVRSEAVKGN----LNFVLSFLESSTL-PLPLH-SLRGSLILGFK----RC-
------MNINL-WSKITELLYKDGRYCQEPAGPT-EAVGYFLYNLIDSMSDSEVQAKEEH
LRQYFHQLKEMNIQISENIYRGIRNLLDSYHVPELIKDVNILVDKEKIDSR----KIAQL
KSSELESTLEKLKDANQPIGDVLKQLIIVLCSEENMQKALELKAKYESD-MVVGG

PF01535 // ENSGT00390000016775_0_Domain_11 (836, 871)

YAALI
NLCCRHDNAEDALNL-------------KQ

ENSGT00390000016775_0_Linker_11_12 (871, 888)

EFDRLYSSAVLDTNKYV

PF01535 // ENSGT00390000016775_0_Domain_12 (888, 914)

GLVKVLGKHGKLQ
DAINILKEMKEKD

ENSGT00390000016775_0_Linker_12_13 (914, 1100)

VLIKDATVLSFFHILNGAALRGEIETVKQLHEAIVTLGLAKPSANIS
VPLVTVHLEK-GDLPAALETTIDC---YKKYKILPRLHDVLCKLI-EKGETDLIQKAMDF
VSQEQGEMTMLYDIFFAFLQTGN-YKEAKKIIETPGIRARPTRLQWFCDKCISNNQVETL
EKLVE-LTQKLFECDRDLL

PF01535 // ENSGT00390000016775_0_Domain_13 (1100, 1128)

YYSLLKLYKKNGDWQRADAVWNKMQEENIIPREKTLRLLAE
ILKDSNQEIPFD----VPELWYEEDT-HPPT-----SSPTTVDPLSEKELLKACRQRKNR
-DAFNIFLKGQRQNIMFSSNTYRTLIQLLLLKDSF-TEAMQVK-DVAETHIKGFTLNDAA
NSILIIAQVRRDYLKEALTTLKTALDLDQTPSRLSVTRLIQAFALKGDVQSIEAIQEMVS
GHD-SIGLSAMVFINNIALAQIKNNNMDVAIENIEN--MLTSGNQTIEPQYFGLSYLFRK
AIEEQMETAVEK----------------------------------------LSIMAERL
ANQFSVYKPVTDLFLQLVDSGKMDDARALLQRCGAIAEQTPILLVFCIRSAQKQGKA---
-PVLTSLLELIPELRDKEEAYTSTMRSYALDNDVASAKVLYEHVNAKKMKLNDLFLKRYA
LLLKNAGESVPFTEPPESFEFYAKQLKESGEIPS----------

------------------------------------------------------------
---------------------RAGAAPRLPLSLRL-------FAGGLS--RPHAAPCLPA
ARAGPVAGGLLNQARLYAI-AAEKKNYLQEEPA------SSHRRNASQFDWALMRLDNSV
RRTGRIPKTLLQKVFDNTCH-SGSPGGNQALLLLRSCGSLLPELQLSERTEFAHRIWDKL
QKLGTVYDVSHYNALLKVYLQNEYKFSPTDFLAKMEEANIQPNR

PF01535 // ENSGT00390000016775_0_Domain_6 (285, 319)

VTYQRLIAAYCNMGDI
EGASKILGFMKTKDLPVT

ENSGT00390000016775_0_Linker_6_8 (319, 320)

E

PF01535 // ENSGT00390000016775_0_Domain_8 (320, 355)

AVFSALVTGHARAGDIENAENILTV-MKEAGIEPG

ENSGT00390000016775_0_Linker_8_7 (355, 356)

P

PF01535 // ENSGT00390000016775_0_Domain_7 (356, 390)

DTYLT
LLNAYAEKGDIDRVKQTLEKVEKSDLYLMDRDLLQIIFSFSKAGYSQYVPEILEKITYER
RYIPDAMNLILLLVTEKLEDTAFQILLACPVSRE-------DGLSDFVGFFLQHCVTMNT
PAEKLKDYCRKLKESQMHTSPLQFTLQSALLANKTDLAKALMKALKEEGF-PVRI

PF01535 // ENSGT00390000016775_0_Domain_10 (536, 570)

HYFWP
LLVGHQKEKDVQGIIEVLKAMHEMGVSPD

ENSGT00390000016775_0_Linker_10_11 (570, 834)

QETYINYVFPSFDSVRSAHAVLQENGYLPES
S--VFSQAELRSEAVSGN----LAYILSFLQSNTQ-PLPLI-SLRNTLSLGFR----RC-
------MDINL-WSKITELLYKNGLYCQEPSGPT-EAVGYFLYNLIDSMSDSEVQAKEEC
LRQYFHQLKKMNVKIPENIYRGIRNLLDSYHVPELIKDINILVEREKTDSR----KTAQL
PSSALESTLEKLKDTNQPIGDVLKQLILALCSEENMQKALEVKAKYESD-MVV

PF01535 // ENSGT00390000016775_0_Domain_11 (834, 881)

GGYAALI
NLCCRHDNAEDALNL-------------KQEFDRLDSSAV

ENSGT00390000016775_0_Linker_11_12 (881, 884)

LDT

PF01535 // ENSGT00390000016775_0_Domain_12 (884, 918)

GKYVGLVKVLGKHGKLQ
DAINILKEMKEKDVLIK

ENSGT00390000016775_0_Linker_12_13 (918, 1098)

DATVLSFFHILNGAALRGETETVEQLHEAIMTLGLTKPSASLS
SPLVTLYLEK-DDLGAALEVSINC---YEKYKVLPRIHDILCKLV-EKGETDLIQKAMNF
VSQQQGEMTMLYDLFFAFLQTGN-YKEAKKIIETPGIRARSARLQWFCDRCISSNQVEVL
EKLVE-LTQKLFECDRD

PF01535 // ENSGT00390000016775_0_Domain_13 (1098, 1132)

QLYYSLLKLYKINGDWQKADAVWNKMQEENIIPRAKTLRLLAE
ILRNSNQEVPFD----VPELWYEDEK-HSVN---S-SPPSHAESNIQKDLLNACQQRKSK
-DAYAIFLKAQKENIVLNSETYSSLIKLLLEKDCF-LEAVQVK-KLAETHIKGFTLNDAA
NSLLIITQVRWDYLKEALTTLRTALDLEQIPSRVAVTRLIQACALKGDVESIQAIQMMVD
GYEHSIGLSHMVFINNIALAQIKNNNIDVAIENIEN--MLTSENQTMEPQYFGLAYLFRK
VIEEQLEPAVEK----------------------------------------ISIMAERL
ANQFAVYKPVTDLFLQLLDSGRVDDARALLQRCGAIAEQTSIFLVFCLRSAQRPGKA---
-STLKSLLELIPELIEKE

PF01535 // ENSGT00390000016775_0_Domain_20 (1519, 1553)

ETYTSVMKSYALDKDAVSAKALYEHLTARNIKLNDLFLKRYA
VLLKKAGEPVPFTEPP----------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------ITELLYKDGRYCQEPPGPR-EAVGYFLYNLIGSMSDSEVQANEEH
LRQYFHQLKEMNIKIYENIYRGIRNLLDSYHVPELIKDVNILVEREKRDSQ----KIC--
RSSDLEATLEKLKDNNQPIGDVLKQLILTLCSEENMQKALEVKTKYESD-MVVS

PF01535 // ENSGT00390000016775_0_Domain_11 (835, 873)

SYAALI
NLCCRHDNAEDALNL-------------KQEF

ENSGT00390000016775_0_Linker_11_12 (873, 888)

ERLDSSAVLHTNKYV

PF01535 // ENSGT00390000016775_0_Domain_12 (888, 914)

GLVKVLGKHGKLQ
DAINILKEMKEKN

ENSGT00390000016775_0_Linker_12_13 (914, 1100)

VPIQDATLLSFFHILNGAALRGEIETVKQLHEAIVTLGLAKPSTNIS
FPLVTVHLEK-GDLLAALEAMIVC---YKKYKILPRMHDVLCKLV-EKGETDLIQKAMDF
VSQEQGEMTMLYDIFFAFLQTGN-YKEAKKIMETPGIRARPTKLQWFCDRCITNNKREAL
EKLVE-LTQNLFECDRDQL

PF01535 // ENSGT00390000016775_0_Domain_13 (1100, 1128)

YYSLLKLYKKNGDWQRADAIWNKMQEENIIPREKTLRLLAD
ILKDNNQEVPFD----VPELWYDDDE-HSPN-----SSPRPVDPLTEKAVLNACQQRKNR
-DAYNIFLRAQRQNIIFSSDTYRTLTQLLLLTDNF-TQAIEVK-MAAETHIKGFTLNDAA
NSFLIIAQVRRDYLKEALTTLKTALDLDQTPSKLSVTRLIQAFASKGDVQSVEAIQKMVS
GHD-SIGLSGMIFINNIALAQIKNNNIDVAIENIEN--MLTSGNQTIESRYFGLSYLFRK
AIEEQIEPAVEK----------------------------------------LSIMAERL
ANQFAVYKPVTDLFLQLVQLGKVDDARALLQRCGAIAEQTPILLVFCFRIAQQKGKA---
-PVLNSLLELIPELREKEEAYTSAMKTYVLDNDVPSAKMLYKYLTAKNMKMNDLFLKRYA
LLLKNAGEPVPFIEPPESFEFYSKQLKESKENPS----------

------------------------------------------------------------
---------MAALLRPARWLLRAGFAPQLPLSLRL-------LAGGPG--RPHAVPCLPA
ARAGSVAGGLLNPARLYAI-AVEKKNDIQEEPT------SSLRRTASQFDWALMRLDNSV
RRTGRIPKTLLQKVFDNTCH-SGIPGGNQALLLLRSCGSLLPELKLTERTEFAH

PF13812 // ENSGT00390000016775_0_Domain_5 (235, 295)

RIWDKL
QELGTVYDVSHYNALLKVYLQNEYKFSPTDFLAKMEEANIQPNRVTYQRLIAAY

ENSGT00390000016775_0_Linker_5_7 (295, 306)

CNVGDI
EGASK

PF13812 // ENSGT00390000016775_0_Domain_7 (306, 366)

ILGFMKTKDLPVTEVVFSALVTGHARAGDMENAENILTV-MKEAGIEPGPDTYLA
LLNAYAEKGDIDHVKQTLEQVEKSELYLMDRDLLQLIFSFSKAGYPQYASEILEKIKYERRYIPDAMNLILLLVTEKLEDTALQILLACPISRE-------DGLSDFGSFFLQHCVTMNTPAEKLTDYCRKLKEAQMHSSPLQFTLYCALLHNKADLAKALMKAMKEEGF-PVRTHYFWPLLVEHQKKKNAQGIIEVLKGMHELGVDPDQETYVNYVFPSFESVKSVHTILQENGCLPKSD--TFSQAELRSETVNGN----LEYVLSFLKSNTL-PFSFN-SLRGSLILGFR----------------------ITELLYKDGRYCQEPPGPT-EAVGYFLYNLIDSMSDSEVQAKEERLRQYFHQLKEMNVKIPENIYRGIRNLLDSHHVPELIKDVYVLVDKEKIDSR----KTVQFASSDLESTLERLKAENQPVGDVLKQLILVLCSEENMQKALELKAKYESD-MVIGGYAALINLCCRHDNAEEALNL-------------KQEFDRLYSSAVLDTGKYVGLVKVLGKHGKLQDAINILKEMKEKDVLIKDATVLSFFHLLNGAALRGEIETVKQLHEAIMTLGLAKPSSSLCSPLVTVYLEK-DDSPAALEATIDC---FRKYKILPRIHDVLCKLI-EKGETDLIQKAMDFVSQEQGEMTMLYDLFFAFLQTGN-YKEAKKIIETPGIRARPARLNWFCDRCITSNQVETLEKLVE-LTQKLFECDRDQMYYNLLKLYKINGDWKRADAVWNKMQEENVIPREKTLRLLAEILRNSNQEVPFD----VPELWYEDEK-DSQY---SSPSTSPVESDLQKDVLKACQDKNNT-DAYDIFLKAQEQNVVFKSKTYNILIKLLLSKECL-AQAIHVK-DFAETHIKGFTLNDAANSLLIITQVRRDYLKEALTTLETALNLKQIPSKVAVTRLIQAFALKGDVEGIEEIQKMVNGLEDSIGLSNMVFINNIALAQIKNNNIDVAIENIEN--MLTSENQTVDPQYFGLSYLFRKVIEEQLEPAVEK----------------------------------------ISIMAERLANQFAVYKPVTDLFLQYVEAGKVDDARALLQRCGAIAEQIPIFEVFLVRNSRKPGKA----PTLQSLLGLIPELADKEAAYTSLMKSYALDKDVTSAKALYEHL

PF13812 // ENSGT00390000016775_0_Domain_8 (306, 366)

ILGFMKTKDLPVTEVVFSALVTGHARAGDMENAENILTV-MKEAGIEPGPDTYLALLNAYAEKGDIDHVKQTLEQVEKSELYLMDRDLLQLIFSFSKAGYPQYASEILEKIKYER
RYIPDAMNLILLLVTEKLEDTALQILLACPISRE-------DGLSDFGSFFLQHCVTMNT
PAEKLTDYCRKLKEAQMHSSPLQFTLYCALLHNKADLAKALMKAMKEEGF-PVRTHYFWP
LLVEHQKKKNAQGIIEVLKGMHELGVDPDQETYVNYVFPSFESVKSVHTILQENGCLPKS
D--TFSQAELRSETVNGN----LEYVLSFLKSNTL-PFSFN-SLRGSLILGFR-------
---------------ITELLYKDGRYCQEPPGPT-EAVGYFLYNLIDSMSDSEVQAKEER
LRQYFHQLKEMNVKIPENIYRGIRNLLDSHHVPELIKDVYVLVDKEKIDSR----KTVQF
ASSDLESTLERLKAENQPVGDVLKQLILVLCSEENMQKALELKAKYESD-MVIGG

PF01535 // ENSGT00390000016775_0_Domain_11 (836, 871)

YAALI
NLCCRHDNAEEALNL-------------KQ

ENSGT00390000016775_0_Linker_11_12 (871, 888)

EFDRLYSSAVLDTGKYV

PF01535 // ENSGT00390000016775_0_Domain_12 (888, 914)

GLVKVLGKHGKLQ
DAINILKEMKEKD

ENSGT00390000016775_0_Linker_12_13 (914, 1099)

VLIKDATVLSFFHLLNGAALRGEIETVKQLHEAIMTLGLAKPSSSLC
SPLVTVYLEK-DDSPAALEATIDC---FRKYKILPRIHDVLCKLI-EKGETDLIQKAMDF
VSQEQGEMTMLYDLFFAFLQTGN-YKEAKKIIETPGIRARPARLNWFCDRCITSNQVETL
EKLVE-LTQKLFECDRDQ

PF01535 // ENSGT00390000016775_0_Domain_13 (1099, 1128)

MYYNLLKLYKINGDWKRADAVWNKMQEENVIPREKTLRLLAE
ILRNSNQEVPFD----VPELWYEDEK-DSQY---SSPSTSPVESDLQKDVLKACQDKNNT
-DAYDIFLKAQEQNVVFKSKTYNILIKLLLSKECL-AQAIHVK-DFAETHIKGFTLNDAA
NSLLIITQVRRDYLKEALTTLETALNLKQIPSKVAVTRLIQAFALKGDVEGIEEIQKMVN
GLEDSIGLSNMVFINNIALAQIKNNNIDVAIENIEN--MLTSENQTVDPQYFGLSYLFRK
VIEEQLEPAVEK----------------------------------------ISIMAERL
ANQFAVYKPVTDLFLQYVEAGKVDDARALLQRCGAIAEQIPIFEVFLVRNSRKPGKA---
-PTLQSLLGLIPELADKEAAYTSLMKSYALDKDVTSAKALYEHLTAKNVKLNDLCLKRYA
CLLKNAGEPVPFPEPPESFEFYAKQLKESKENSL----------

------------------------------------------------------------
---------MAALLRPARWLLGAAATPRLPLTLRL-------LAGGPG--RLFSVSRVAA
AGGKPPAGELLSQARLYAI-AAE-KRDLQEEPA-------PMRRNSSQFDWALMRLNNSV
RRTGRITKGLLQKVFESTCR-SESPGGNQALLLLRSCGSLLPELSLAERTEFAHKIWDKL
EKLGTVYDVSHYNALLKVYLQNEYKFSPTDFLAKMERANIQPNRVTYQRLIAAYCNVGDI
EGASKILGF

PF17177 // ENSGT00390000016775_0_Domain_7 (310, 418)

MKTKDLPITEAVFSALVTGHARAGDMENAENILTV-MKEAGIEPGPDTYLA
LLNAYAEKGDIDHVKQTLENVEKLDHYLTDRDLLHIIVTFSKAGYPQYVSQILEKVTYER
RYIPDAMNLILLLVTEKLEDTAFQILLALPMSKE-------ESMNTFGSFFLRHCVTMNT
PTEKLIDYCKKLKEAKLHSSPLQFTLQCALLNNKTALAKAVMQALKEEGF-PIRPHYFWP
LLVEHKKTKNLEGIMDILKIMTELGVDPDQDTYVNYVFPCFDNVASFRAALQENGCLPKS
N--KFAQAEMRSEAMNGN----LQNILSLLESNEL-PLSMN-SFRNSLILGFR----RS-
------MDIDL-WSKITELLYKDRRYCREPSAAT-EAVGYFLYHLIDSMSDSEVQAKEEH
LRQYFHQLKKMNVKVPENIYKGIRNLLDGYHVPELIKDVKVLVDKEKVDSW----KTSQL
TPSDLESKLEKLQADNQPIGDVLKQLILLLCSEENMEKALEVKAKYESD-MVIGG

PF01535 // ENSGT00390000016775_0_Domain_11 (836, 871)

YAALI
NLCCRHDNAEDALNL-------------KQ

ENSGT00390000016775_0_Linker_11_12 (871, 889)

EFDRLYPSAVLDTVKYIR

PF01535 // ENSGT00390000016775_0_Domain_12 (889, 914)

LIKVLGKHGKLQ
DAIKILKEMKEKDVAIQDSTVMSFFHVLNGAALRGEIETVKQLHEAIVTLGLAKPSTSIS
IPLVTMYLEK-DDLPAALEACIDC---HEKYKVLPRIHDVLCKLI-EKGETDLIQKAMDF
VSHEQGEMTMLYDLFFAFLQTGN-YKEAKKIIETPGIRARPARLQWFCDRCITANQVETL
EKLVE-LTEKLFECDRDQMYYNLLRLHKMNSDWQRADTVWNKMQEENVIPRERTLQLLAE
ILKTSNQEVPFD----VPELWFEDDS-SSLS---S-SSPPAVETITEKMLLDTCNRRKNK
-DAYNIFLKAQRQNIVFSSKTYSTLISLLLRRDSF-TEAMQVK-DFAETHIKGFTLNDAA
NSLLIIAQVRRDYLKVALETLKAALALQQAPSQVAITRLIQACALKGDLESIEAIREMVN
GLD-KIRLSKMVFINNTALAQMKNNNIDVAIENIEQ--KLMSENQTIDPKYFDLSYLFRK
VIEEQMETALER----------------------------------------LSIMSERL
ANQFSIYKPVTDLFLQLLDSGKVDEAKALLERCGAIAEQSTVLLVFCRRNCQKPKKA---
-PVLKTLLELIPELRDKEDAYSCSMRSYALDKDVASAKELYEYLTAKNMPIDDLFLKRYA
TLLKEVGEPVPFTEPPESFEFYVKQLKEARENPS----------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------QFDWALNRLDNSV
RKTGRIPKTLLLKVFQEICREAGCPGSNQILLLL

PF01535 // ENSGT00390000016775_0_Domain_1 (215, 249)

RSCGALLPEVLSSERTELAHTIWDKM
KEMGAVYDTSHYNALLKVYLQNEHKFSPTEFLARMEEANVQPNR

PF01535 // ENSGT00390000016775_0_Domain_6 (285, 319)

VTYQRLIAAYCNEGDI
EGASKILGFMKSKDLPIT

ENSGT00390000016775_0_Linker_6_8 (319, 320)

E

PF01535 // ENSGT00390000016775_0_Domain_8 (320, 355)

AVFSSLVKGHARSGDIKSAENILSV-MKMAGVEPG

ENSGT00390000016775_0_Linker_8_7 (355, 356)

P

PF01535 // ENSGT00390000016775_0_Domain_7 (356, 390)

DTYLS
LLNVYAEKGDADSIKKTLEEVEKTEGYLM

ENSGT00390000016775_0_Linker_7_9 (390, 500)

DRILMQVIFSLAKAGYPQYIEDIKERIRFEK
ELIPDAMNLCLTLITHGFEDISFRILKSYNHLSR--------DNADQGSFFLQHCVNRDL
PLSKLKQFCSELKETKMHS

PF01535 // ENSGT00390000016775_0_Domain_9 (500, 535)

APLTFVLRCALEANKSALAIGVMKTMKEEGV-PLR

ENSGT00390000016775_0_Linker_9_10 (535, 536)

P

PF01535 // ENSGT00390000016775_0_Domain_10 (536, 570)

HYFWP
LMVGFQKEKNLKGIFEILKVMHELGVEID

ENSGT00390000016775_0_Linker_10_11 (570, 834)

AETYTGYVLKNFPDCKTACAQLKENNCLFET
V--GLCVAQIRHEAAHGR----LNNVLSLLSSASTPSVDFN-QFRNSLIRGFK----SS-
------NDVQL-WSKITELLYKDERYCLTPPGPT-EAVGYFLYHLIDSMSDSEVQAKEER
LRQYFHQLKKMNIVIPTNLCSGICRLLDSSQVPELIKDVRSLSPK-KPMSTDSIPESAKS
DVSALEKKLEKRKAENQPITDVLKQLIHALCEEENMQKALEVKAKYEPD-MVV

PF01535 // ENSGT00390000016775_0_Domain_11 (834, 881)

GGYAALI
NLCCRHDNVEDAMNL-------------KEKVFPRNSPVA

ENSGT00390000016775_0_Linker_11_12 (881, 884)

LDT

PF01535 // ENSGT00390000016775_0_Domain_12 (884, 918)

GKYIALVEVLGKHGRLE
DAINVLTEMKEKDVPIS

ENSGT00390000016775_0_Linker_12_13 (918, 1098)

DRAVASFFRLLNAAAMRGEVETVNRLHETIVNLGLAE-TAALY
SPLITVHLEK-DDMPAALEALMGC---YKKHGKILQLHNIYCRLI-EKGDADLLQKVSDF
ISREYGDMMALYDLFFAFLQTGK-YKEARKVIETPGLRAHPGRLQWFAKKCISNNQMETL
EQLVE-LTQNLFECDRD

PF01535 // ENSGT00390000016775_0_Domain_13 (1098, 1132)

EMYYHLLQLCENNSDWSKAEAIWTKMQEENVVPREKTLTLLAD
IFEKNGQVVPFE----VPKLFVLKARQEETRSPISSTSEERKI-------RMLCKTNNVK
-EAYDFFLQTQE-KG-YQYRTYVTLIKALLSQDSF-EEAIQVK-HIAETHIKGFTLNS

PF01535 // ENSGT00390000016775_0_Domain_19 (1259, 1293)

AA
SSLLIISQVRRDYLKDALAAFQGMLDSGLLPT

ENSGT00390000016775_0_Linker_19_20 (1293, 1519)

RPAVIVLAEALAVKGDMKNLKAFGNMIE
DITKSIDLSPSLMANAIALAHAKNNDLDAAVEYLEP--LLISGAQNPDQPVKNISFLLRK
VSEEGLEPALEK----------------------------------------FGVMAERL
ANQFGIYRPVTDLFLQYVSAGRVDDARSLLQRCGGLVEEKRTFLNFMGKAATKPGQA---
-KKIETLLELIPDHLDME

PF01535 // ENSGT00390000016775_0_Domain_20 (1519, 1553)

TAYRFLLKCYELDGDVASVKAAYEKSKEKNIQLHDLSLKSLA
VFLKKVGEPVPFTEPPETFKFYMEKWKKRRSETL----------

------------------------------------------------------------
------------------------------------------------------------
---------LINETRLYST-VAQKKSDLQEESI------SIYKKQLNQFDWALTKLDNSV
RRTGRIPKTLLQNIFHDVCR-SGNPSSNLALLLLRSCGSLLPELKPSERTEFVHRIWNKL
QQLGVTYDISHYNALLKVYLQNQHKLSPTDFLAKMEEANIQPNR

PF01535 // ENSGT00390000016775_0_Domain_6 (285, 314)

VTYQRLIAAYCNEGDI
EGASKILGFMKTK

ENSGT00390000016775_0_Linker_6_8 (314, 321)

DLPVTEI

PF01535 // ENSGT00390000016775_0_Domain_8 (321, 351)

VFSTLVTGHARAGDMQNAENILSV-MREAGIEPGPDTYLT
LLSAYAEKGDIDNVRKTLETIEKTDNYLMDRDLMQIIFSFSKAGYPQYVSEILERMKYER
RYIPDVMNLCLSLVTERLEDVAMQILMSCPKSVLENTQENSSNLNNFGNFFLQHCVTMNT
PFNKLEEFCQKLKEEKLHVAPLQFSLYCALKDRKTALAADLMKAMKEQKT-PIRPHYFWP
LLTGHQKNKNIQGIIEIVQKMHELGVNPDSETYGNYVFPSFDSIQSARSVLQENECPVNE
D--LFFLAELRNEALNGN----LEKVLSLLESSKS-PLDLN-SFRGSLILGFR----RS-
------NDISL-WSKITEHLYTDGRYCQAPPGPT-EAVGYFLYNLIDSMSDSEVQAKEER
LRQYFHQLKKMNIAIPERIFKGIRNRLNSHHVPELIKDAALLVDRETSDSS----KFLMA
KAGDLEQKLENLKTEKQPIGDVLKQLILLLCSEENLQKALEIKTKYESD-MVVGG

PF01535 // ENSGT00390000016775_0_Domain_11 (836, 869)

YAALI
NLCCRHNNAEDALNL-------------

ENSGT00390000016775_0_Linker_11_12 (869, 886)

KQQIDRIDSSVSLDPGK

PF01535 // ENSGT00390000016775_0_Domain_12 (886, 914)

YLALVKVLVKHDRLL
DAINILKEIKEKDVLLKDRL--AFFHILNEAALLGKVETVKQLHETIMTLGLAKPSTSLC
SPLVTLHLEK-DDIPAALEATVDC---YKKYGIMPKIHEVLCKLI-EKGETDLIQKAMDF
VTQEQGEMTMLYDLFFAFMQTGN-YKEAKKIIETPGIRARPGKLQWFSERCISSNQVETL
EKLVE-LTQKLFECDRDQMYYNLLMLCKENNDWQRADAVWTKMQEENIIPRQKTLKLLGE
ILRDNNQEVPFD----IPTLWYDDSV-EADS--HHAMLPPPPDMFLRKDLLNACQNKKSE
-DAYAIFLEAQKKNLVFSSLIYSSLIKLLLANGSL-EEALNVK-EVAETHIKGFTLNDAA
SSLLIITQVRRDYLKDALTTLKATLDSDQLPSPLSVTRLIQALALKGDKETIQVIEKMLQ
DVQNPIRLSSMVFINNNALAEIKNNNLDAAVNYLES--LFTSGFLSSNKQQSSIAYLLRK
VIEEQLEPAVEK----------------------------------------LSIMVERL
AHQFGHYRPVTDLFLEYIRSGRMDDARALLQRCGAIAEQTPVLLGFFLKNSKIQGQT---
-HILKSLLEVIPDLTLNPE

PF01535 // ENSGT00390000016775_0_Domain_20 (1520, 1549)

IYSFLMRSYGLDRDTASAKALYEEMKAKNIKMDNIFLKQYA
ILLKNAGEPVPFTEPPESFKFYIEQMKQEVLAPAPS--------

------------------------------------------------------------
---------MAALLRSARWLLRAGAAPRLPLSLRL------LPGGP-G--RLHAASYLPA
ARAGPVAGGLLSPARLYAI-AAKEKDI-QEES------TFSSRKISNQFDWALMRLDLSV
RRTGRIPKKLLQKVFNDTCRS-GGLGGSHALLLLRSCGSLLPELKLEERTEFAH

PF13812 // ENSGT00390000016775_0_Domain_5 (235, 294)

RIWDTL
QKLGAVYDVSHYNALLKVYLQNEYKFSPTDFLAKMEEANIQPNRVTYQRLIAS

ENSGT00390000016775_0_Linker_5_7 (294, 309)

YCNVGDI
EGASKILG

PF17177 // ENSGT00390000016775_0_Domain_7 (309, 417)

FMKTKDLPVTEAVFSALVTGHARAGDMENAENILTV-MRDAGIEPGPDTYLA
LLNAYAEKGDIDHVKQTLEKVEKSELHLMDRDLLQIIFSFSKAGYPQYVSEILEKVTCER
RYIPDAMNLILLLVTEKLEDVALQILLACPVSKE-------DGPSVFGSFFLQHCVTMNT
PVEKLTDYCKKLKEVQMHSFPLQFTLHCALLANKTDLAKALMKAVKEEGF-PIRPHYFWP
LLVGRRKEKNVQGIIEILKGMQELGVHPDQETYTDYVIPCFDSVNSARAILQENGCLSDS
D--MFSQAGLRSEAANGN----LDFVLSFLKSNTL-PISLQ-SIRSSLLLGFR----R--
-----SMNINL-WSEITELLYKDGRYCQEPRGPT-EAVGYFLYNLIDSMSDSEVQAKEEH
LRQYFHQLEKMNVKIPENIYRGIRNLLESYHVPELIKDAHLLVESKNLDFQ----KTVQL
TSSELESTLETLKAENQPIRDVLKQLILVLCSEENMQKALELKAKYESD-MVTGG

PF01535 // ENSGT00390000016775_0_Domain_11 (836, 871)

YAALI
NLCCRHDKVEDALNL-------------KE

ENSGT00390000016775_0_Linker_11_12 (871, 888)

EFDRLDSSAVLDTGKYV

PF01535 // ENSGT00390000016775_0_Domain_12 (888, 914)

GLVRVLAKHGKLQ
DAINILKEMKEKDVLIKDTTALSFFHMLNGAALRGEIETVKQLHEAIVTLGLAEPSTNIS
FPLVTVHLEK-GDLSTALEVAIDC---YEKYKVLPRIHDVLCKLV-EKGETDLIQKAMDF
VSQEQGEMVMLYDLFFAFLQTGN-YKEAKKIIETPGIRARSARLQWFCDRCVANNQVETL
EKLVE-LTQKLFECDRDQMYYNLLKLYKINGDWQRADAVWNKIQEENVIPREKTLRLLAE
ILREGNQEVPFD----VPELWYEDEK-HSLNS----SSASTTEPDFQKDILIACRLNQKK
-GAYDIFLNAKEQNIVFNAETYSNLIKLLMSEDYF-TQAMEVK-AFAETHIKGFTLNDAA
NSRLIITQVRRDYLKEAVTTLKTVLDQQQTPSRLAVTRVIQALAMKGDVENIEVVQKMLN
GLEDSIGLSKMVFINNIALAQIKNNNIDAAIENIEN--MLTSENKVIEPQYFGLAYLFRK
VIEEQLEPAVEK----------------------------------------ISIMAERL
ANQFAIYKPVTDFFLQLVDAGKVDDARALLQRCGAIAEQTPILLLFLLRNSRKQGKA---
-STVKSVLELIPELNEKEE

PF01535 // ENSGT00390000016775_0_Domain_20 (1520, 1544)

AYNSLMKSYVSEKDVTSAKALYEHLTAKNTKLDDLFLKRYA
SLLKYAGEPVPFIEPPESFEFYAQQLRKLRENSS----------

------------------------------------------------------------
---------MAALLRPARFLLRAADGSHLPPALRL-------L-----------------
-------PGLQSQARHYAIAA---ENRWTEEP------TFSSRRVGGQFDWALERLDNSV
RRTGRIPRSLLQKVFTNTCHS-GTPGGNQALLLLRSCGSLLPELEFSERTKLAHVIWEKL
QKLGTVYDV

PF01535 // ENSGT00390000016775_0_Domain_5 (250, 284)

SHYNALLKVYLQNGYKFSPMDFLAQMEAANVQPNRVTYQRLIAAYCNVGDI
EGAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDMENAENILTV-MSEAGIEPGP

PF01535 // ENSGT00390000016775_0_Domain_7 (356, 390)

DTYLA
LLNAYAEKGDMDHVRQTLERVTTSELYLMDRDLLQIIFSFSKAGYPQYATEILGKLTHER
RYIPDAMNLILHLVTEKLEDVAFQVLVAIPMSKE-------DRLSDFGNFFLRHCVAMNT
SAEKLKEYCKKLQETQLHSSPLQFTLHCALLAKKTDLVKELLKALKEEGF-PIRTHYFWP
LLVGHLKEKNVQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXENDCLSEE
SISILSQIQMKHEAENGN----LDYFFSFLKSNPT-ELLLGTSLKNSLILCFR----XXX
XXXXXXXX---------XXXXXXXXXXXXXXXXXXXAVGYFLYSLIDSMSDSEVQAKEEH
LRQYFHQLKEMNINISENIYRGIRNLLDSHHVPDLIKDIRMLISKTDSQ-N----SVQQF
ASSELESTLERLKDENQPIKDVLKKLILKLCSEEXXXXXXXXXXXXXXX-XXXXXXXXXX
XXXXXXXXXXXXXXX-------------XXXXERLDSSVVLDT

PF01535 // ENSGT00390000016775_0_Domain_12 (884, 918)

GKYIALVRVLTKEGKVQ
DAINILKEMKEKNVLIRDSTALSFFHILNDAALRGEVDTVNQLHEAIVTLGLAKPTLYTV
SPLVTVHLAK-DDLPAAVNVCFKC---YQKYKVLPRFHDVLCKLL-EKGETDLVHKAMGF
VTEEQGEMTMLYDLFFAFLHTGN-YKEAKKIIEXXXXXXXXXXXXXXXXXXXXXXXVETL
EKLVE-LTEKLFECDRDKMYYSLLKLYXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
-XAYQIFLKAQKQNIVFNSDTYSSLIKLLLSKDDF-TNAMHVK-SVAE-TIKGFTLNSAP
SSILIPAQVRRDFLKEALETLSAVCSQEQLPSNISVTRLVQACALKGDVDSVQAVQRMVS
GLEDTLRLSSMLFINNTALAQIKNNNIDVAVEQIEN--MLTSGDQAISPQYFGLSYLFRK
VIDQKLDPALEK----------------------------------------ITIMAERL
ANQFAVYKPVTDLFLQLVEHGKVDDARDLLQRCGAIAEQIPIFRVFFIRNSRRKGM----
------------------------------------------------------------
--------------------------------------------

-MPNRANYFFTQIGFPVLQSQT-----TTASPYAWRAGSLVRPAPVDPAVTCSSCPSEER
ASRRGDSQAMAALLRPARWLLRAGRAARLPLSLRL-------LAGCSG--LPHAVPCLPA
ARSGPIAGGLLSQARLYAI-AAEKKNVLQEEPT------LSPKRNARWFDWALMRLDNSV
RRTGRIPKMLLQRVFDSTCH-SGSPGSNQALLLLRSCGSLLPELTLAERTEFAHQIWEKL
QKLGTVYDVSHYNALLKVYLQNEYKFSPTDFLAKMEEANIQPNR

PF01535 // ENSGT00390000016775_0_Domain_6 (285, 314)

VTYQRLIAAYCNVGDI
EGASKILGFMKTK

ENSGT00390000016775_0_Linker_6_8 (314, 321)

DLPVTEA

PF01535 // ENSGT00390000016775_0_Domain_8 (321, 351)

VFSALVTGHARAGDMENAENILTV-MKEAG

ENSGT00390000016775_0_Linker_8_7 (351, 357)

IEPGPD

PF01535 // ENSGT00390000016775_0_Domain_7 (357, 384)

TYLA
LLNAYAEKGDIDRVKQTLEKVEKSDLYLMDRDLLQIIFSFSKAGYPQYVSEILEKITYER
RYIPDAMNLILLLVTEKLEDTALQILLACPISKE-------DNLTDFGSFFLKHCVTVDT
PVDKLIDYCKKLKEAQMHSSPLQFTLHCALVANKTDLAKALMKTLKEEGF-PVRTHYFWP
LLVGYQKKKNVQGIIEVLKGMHEMGVVPDQETYINYVFPSFDNVQSVRAVLQENGCLPES
D--TFSLAEVRHEALNGN----LAYILSFLESNTT-PFPFN-YLRGSLILGFR----RS-
------MDVNL-WGKITELLYKDGRYCQEPPGPT-EAVGYFLYNLIDSMSDSEVQAKEEL
LRQYFHQLKEMNVKIPDNIYRGIRNLLDSYHVPELIKDVNLLVEREKIDSQ----KTFQP
ASSDLESTLEKLKAQNQPIGDVLKQLILVLCSKENMQKALELKAKYESD-MVLGG

PF01535 // ENSGT00390000016775_0_Domain_11 (836, 871)

YAALI
NLCCRHDNAEDALNL-------------KQ

ENSGT00390000016775_0_Linker_11_12 (871, 888)

EFDRLDSSAVLDTNKYV

PF01535 // ENSGT00390000016775_0_Domain_12 (888, 914)

GLVRVLGKHGKLQ
DAINILKEMKEKD

ENSGT00390000016775_0_Linker_12_13 (914, 1099)

VLIKDATVLSFFHILNGAALRGEIETVKQLHEAIVTLGLAKPSTNIS
SPLVTVYLEK-DNLAAALEVAMDC---YRKYQILPRIHDILCKLI-EKGETDLIQKAMDF
VSQEQGEMTMLYDLFFAFLQTGN-YKEAKKIIETPGIRARPARLQWFCERCISSNQVETL
EKLVE-LTQKLFECDRDQ

PF01535 // ENSGT00390000016775_0_Domain_13 (1099, 1128)

MYYSLLKLYKINGNWQKADAVWNKMQEENVIPREKTLRLLAD
ILRNSNQEVPFD----VPELWCEDEA-GSLS---S-SSPSPLETDIQKHVLKACQMKRNK
-DAYNIFLKAERQNIVFNSETYNSLIKLLLSNNGF-IQAMQVK-DFAETHIKGFTLNDAA
NSLLIITQVRRDYLKEALRTLKAALDLGQTPSRLAVTRLIQAFALKGDVQSIEAIQKMVH
GLD-SIGLSRMVFINNIALAQIKNNNVDVVVENIEN--MLTSGTPTVEPQFFGLAYLFRK
VIEEQLDPAAEK----------------------------------------LSIMAERL
ANQFAVYKPVTDFFLQLVDAGKTDDARALLQRCGAIAEQTPILLVFCIRSSQKPGKA---
-PTLKSLLELIPELTEKEEAYTSAMKSYVLDKDVASAKALYEHLTAKKTKLNDLFLKRYA
VLLKGAGESVPFPEPPESFEFYANQLKESKEKPL----------

------------------------------------------------------------
---------MAALLRPARWLLRARAAPRLPLSLRL-------LASGPR--RPYAAPCVPA
ARAGPVAGGLLSQARPYAI-AVEKNNFLQEEPT-------SHRRNTSQFDWALMRLDNSV
RRTGRIPKTLLQKVFDNTCH-SGSPGGNQALLLLRSCGSLLPELQLSERTEFAHRIWDKL
QKLGTVYDVSHYNALLKVYLQNEYKFSPTDFLAKMEEA

PF12854 // ENSGT00390000016775_0_Domain_6 (279, 311)

NIQPNRVTYQRLIAAYCNAGDI
EGASKILGFM

ENSGT00390000016775_0_Linker_6_8 (311, 321)

KTKDLPVTEA

PF13812 // ENSGT00390000016775_0_Domain_8 (321, 353)

VFSALVTGHARAGDIENAENILTV-MKEAGIE

ENSGT00390000016775_0_Linker_8_7 (353, 357)

PGPD

PF01535 // ENSGT00390000016775_0_Domain_7 (357, 384)

TYLA
LLNAYAEKGDIDHVKQTLEKVEKSDLYLMDRDLLQIIFSFSKAGYSQYVPEILEKITYER
RYIPDAMNLILLLVTEKLEDTAFQILLACAASRE-------DHLSDFGSFFLRHCVTMNT
PAEKLKDYCKKLKESQMHTSPLQITLQCALVANKTDLAKALMKALKEEGF-PVRTHYFWP
LLAGHQKEKNVQGIIEVLKAMHDIGVSPDQETYINYVFPSFNNAKSARAVLQENGCLPES
T--VFSQAELRSEAVNGN----LAYILSFLESNTL-PISSS-SLRGSLSLGFR----RC-
------MDVNL-WSKITELLYKDGRYCQEPPGPT-EAVGYFLYNLIDSMSDSEVQAKEER
LRQYFHQLKEMNVKITENLYRGIRNLLDSYHVPELIKDVNILVDREKIDSR----KTMQL
PSSVLETTLEKLKAENQPIGDVLRQLILALCSEENMEKALQLKAKYESD-MVVGG

PF01535 // ENSGT00390000016775_0_Domain_11 (836, 871)

YAALI
NLCCRHDNAEDALNL-------------KQ

ENSGT00390000016775_0_Linker_11_12 (871, 888)

EFDRLDSSAVLDTSKYV

PF01535 // ENSGT00390000016775_0_Domain_12 (888, 914)

GLVKVLGKHGKLQ
DAINILKEMKEKD

ENSGT00390000016775_0_Linker_12_13 (914, 1100)

VLIKDATLLSFFHILNGAALRGETETVKQLHEAIMTLGLAKPSTALS
SPLVTLYLEK-DDIGAALDITIDC---YEKYKVLPRIHDILCKLI-EKGETDLIQKAMNF
VSQEQGEMTMLYDLFFAFLQTGN-YKEAKKIIETPGIRARSTRLQWFCDKCISTNQVEVL
EKLVE-LTQKLFECDRDQL

PF01535 // ENSGT00390000016775_0_Domain_13 (1100, 1128)

YYSLLKLYKINGDWQRADGVWNKMQEENIIPRAKTLRLLAE
ILRNSNQEVPFD----VPELWYEDEK-HSVN---S-S-PSHAEINIQKDLLKACRQKKSK
-DAHTIFLKAQKQNIVLDSETYSSLIKLLLEKDSL-VEAVHEKIPHAETHIKGFTLNDAA
NSLLIITQVRRDYLKEALTTLKMALDLKQIPSRVAVTRLIQACAMKGDVESIQEIQKMVN
GLEHSIGLSNMVFINNIALAQIKNNNIDVAVENIEN--MLTSGSQTMEPQYFGLSYLFRK
IIEEQMEPAFEK----------------------------------------ISIMAERL
ANQFAVYKPVTDLFLQLLDSGKVDDARALLQRCGAIAEQTSIFLVFCIRNSQRPGKA---
-STLKSLLELIPELVEKEEVYTSAMKSCVLDKDAVSAKVLYENLIARNIKLNDLLLKRYA
VLLKNAGEPVPFTEPPETFKFYRKQLRDSREDPL----------

------------------------------------------------------------
---------MAALLRPASWLLRAGAATRPMLSLRL------L-PGGPG--RPHVVSYLPA
ARAKPVAGGLLGPARLYVI-AAEEKDI-QEES------TFSYRRISSQFDWALMRLDNSV
RRTGRIPKTLLQKVFDNTCSS-GGPGSNHALLLLRSCGSLLPEVKLEERTEFAH

PF13812 // ENSGT00390000016775_0_Domain_5 (235, 296)

RIWDKL
QELGAVYDVSHYNALLKVYLQNEYKFSQTDFLAKMEEANIQPNRVTYQRLIASYC

ENSGT00390000016775_0_Linker_5_7 (296, 308)

NMGDI
EGASKIL

PF17177 // ENSGT00390000016775_0_Domain_7 (308, 417)

GFMKTKDLPITEAVFNSLIRGHARAGDMENAENILTV-MREAGIEPGPDTYLA
LLNAYAEKGDIDHVKQTLEKVEKSELYLTDRDLLQIIFSFAKAGYPQYVSGILEKLTCER
RYIPDAINLILLLVTEKLEDTALQILLACPVSKE-------DSLNDFGNFFLRHCVTMNT
PVEKLTDYCKKLKEVQMHSCPLQFTLSCALLANKTDLAKDLMKAMKEEGF-PIRTHYFWP
LLVGHQKEKNVQGIIEVLKGMQELGVHPNQETYMNYVIPCFDSVLSARAILEENGCLSNS
D--TFSQAALRTEAVKGN----LDYVLSFLESNTS-PLSLQ-SVRGNCICSCL----LLL
----LQCTNFL-SYQITELLYKDPRYCQKPPGPT-EAVGYFLYNLIDSMSDSEVQAKEER
LRQYFHQLKEMNLKIPENTYKGIRNLLDSYHVPELIKDAHMLVDNENLGSR----KTVHL
SSSKLESTIETLKAENQPIKDVLKQLILVLCSEENMQKALEVKAKYESD-MVIAG

PF01535 // ENSGT00390000016775_0_Domain_11 (836, 873)

YAALI
NLCCRHDNAEDALNL-------------KEEL

ENSGT00390000016775_0_Linker_11_12 (873, 886)

DRLDSSAVIDTNK

PF01535 // ENSGT00390000016775_0_Domain_12 (886, 914)

YVALVKVLAKHGKLQ
DAINILKEMKEKD

ENSGT00390000016775_0_Linker_12_13 (914, 1099)

VLIKDATVMSFFHILNGAALRGEIETVKRLHEAIVTLGLAKPSTNIS
FPLVTVYLEK-DDLPAALEVAIDC---CEKYKILPRIHDILCKLI-EKGETDLIQKAMDF
VSQEQGEMMMLYDLFFAFLQTGN-YKEAKKIIETPGIRARPTRLQWFCDRCIASNQVETL
EKLVE-LTQKLFECDRDQ

PF01535 // ENSGT00390000016775_0_Domain_13 (1099, 1128)

MYYSLLKLYKVNGDWQKADAVWNKMQEENIIPREKTLRLLAE
ILRDGNQEVPFD----VPELWYEDEK-LSLDSSLNSSSTSVADPRFQNDILKACRLKQSK
-GAYDIFLKAKRQNVVFNAETYNDLLKLLLSKEHF-TQAMEVK-KFAETHIKGFTLNDAA
NSFLIITQVRRDYLKEALTTLKTALDQQQIPYQLAVTRLIQALAMKGDVENIEAVQKMVN
GLEDSIGLSHMVFINNIALAQIKNNNIDVAIENIEN--MLTSENQVLEPQYFGFAYLFRK
VLEEQLQPAVEK----------------------------------------ISIMAERL
ANQFAIYKPVTDFFLQLVEAGKVDDARALLQRCGAIAEQTSILLVFFIRNSGKPGKA---
-STLKSVLELIPELNEKQE

PF01535 // ENSGT00390000016775_0_Domain_20 (1520, 1548)

AYNSLMKSYASERDVTSAKALYERLTAKNIKPNDLFLKRYA
FLLKSAGESVPFTEPPENFEFYAQQIKESKENSS----------

MSITLTPLFSEKCGFPSSNLKRSLAPPTFGAPCSWSLPRQATLR-----SRAPPVLLVER
ASSCGDVRAMAALLRSSCWLLRAGAAPRLPLSLRL------LTGG-PG--RPHAASYLPA
ARAGPVAGGLLSPARLYVI-AAEKKDI-QEES------TFSSRRIANHFDWALMRLDNSV
RRTGRIPKMLLQKVFDDTCRS-GGPGSSHALLLVRSCGSLLPELKPEERTEFAH

PF13812 // ENSGT00390000016775_0_Domain_5 (235, 296)

RIWDKL
QKLGAVYDVSHYNALLKVYLQNEYKFSPTDFLAKMEEANIQPNRVTYQRLIASYC

ENSGT00390000016775_0_Linker_5_7 (296, 309)

NMGDI
EGASKILG

PF17177 // ENSGT00390000016775_0_Domain_7 (309, 417)

FMKTKDLPVTEAVFSALVTGHARAGDMENAENILTV-MREAGIEPGPDTYLA
LLNAYAEKGDIDHVKQTLEKVEKSELHLMDRDLFQIIFSFSKAGYPQYVSEILEKVTCER
RYIPDAMNLILLLVTEKLEDVALQILLSCPISKE-------DGISDFGSFFLRHCVTMNT
PVEKLTDYCKKLKEIQMHSFPLQFTLHCALLAKKTDLAKALMKAVKEEGF-PIRTHYFWP
LLVGHQKEKNVQGIIEVLKVMQELGVPPDQETYIGYVIPCFNSIKSARAILQENGCLSNS
D--TFSQAELRSEAINGN----LDFVLSFLESNTL-PLSLQ-SIRSSLLLGFR----RS-
------MNINL-WSKITELLYKDGRYCPEPPGPT-EAVGYFLYNLIDSMSDSEVQAKEER
LRQYFHQLKEMNVKIPENICRGIRNLLDSYHVPELIKDAYMLVDSENLDSQ----KTVQL
SSSELESRLETLKAEDQPIRDVLKHLILTLCSQENMQKALELKAKYESD-MVISG

PF01535 // ENSGT00390000016775_0_Domain_11 (836, 871)

YAALI
NLCCRHDNAEDALNL-------------KE

ENSGT00390000016775_0_Linker_11_12 (871, 888)

EFDRLDSSALLDTSKYV

PF01535 // ENSGT00390000016775_0_Domain_12 (888, 914)

GLVRVLAKRGRLQ
DAINILKEMKKKDVPIKDSTVLSFFHILNGAALRGEIETVKQLHEAIVTLGLAKPSTNIS
FPLVTVYLEK-DDPSTALDVAIDC---CEKYKILPRMHDILCKLI-EKGETDLIQKAMDF
VSQEQGEMIMLYDLFFAFLQTGN-YKEAKKIIETPGIRARSTKLQWFCDKCVANNQVETL
EKLVE-LTQKLFECDRDQMYYNLLKLYKMNGDWQRADAVWNKIQEENIIPREKTLRLLAE
ILRDGNQEVPFE----VPE-LYEDEK-HSLNSSLDSSSDSTTELGFQKDILNACQWKQSK
-EAYGIFLKAKQQNVVFNAETYSDLIKLLLSKGYF-TQAVEVK-AFAETHIKGFTLNDAA
NSLLIITQVRRDYLKEALTTLKTALDQQQIPSEIAVTRLIQALAMKGDVENIEVVQKMVN
GLEDSIGLSKMVFINNTALAQIKNNNIDVAIENIEN--MLTSENPGIEPQYFGLAYLFRK
VIEEQLEPAVEK----------------------------------------ISIMAERL
ANQFAIYKPVTDFFLQLVDAGKVDDARALLQRCGAIAEQTSILLVFFLRNSGKRGKA---
-STLKSLLELIPELNEKEEAYSSLMKSYVSEKDVTSAKALYEHLTAKNTKLDDLFLKRYA
VLLKNAGESVPFTEPPESFEFYVQQVKELRENSS----------

------------------------------------------------------------
------------------------------------------------------------
---------LISEANTYST-IAQKKNDHQEESI------SIYKKQMNQFDWALERLDHSV
RRTGRITKTLLQNIYREICR-SGNPSSNLALLLLRSCGSLLPELKPSERTEFVHRIWDKL
QELGVTYDISHYNALLKVYLQNEHEFSPTDFLAKMEEANIQPNR

PF01535 // ENSGT00390000016775_0_Domain_6 (285, 315)

VTYQRLIAAYCNKGDI
EGASKILGFMKTKN

ENSGT00390000016775_0_Linker_6_8 (315, 321)

IPVTEI

PF01535 // ENSGT00390000016775_0_Domain_8 (321, 351)

VFSTLITGHARTGDMQNAENILSV-MREAG

ENSGT00390000016775_0_Linker_8_7 (351, 357)

IEPGPD

PF01535 // ENSGT00390000016775_0_Domain_7 (357, 383)

TYLA
LLNAYAEKGDIDHVIQTLEMMEKTDNYLMDRDLMQIIFSFSKAGYPQYVSEILERMKFER
RCIPDVMNLCLNLVTEGLEDVAVQILVSCPKSLIGKTNES---ATNFGNFFLQHCVTMNT
PFNKLEEFCEKLKEEKLHAAPLEFTLLSALKAKKTDLATDLMKALKEQKA-PIRPHYFWP
LLTKHQKNKDIQGIIKIVKRMHELGVNPDAETYGNYVFPSFNSIQSARAVLQENGCPVDD
N--ILDLAELRNEAVNGN----LERVLSLLTSFKS-SMDLN-SFRGSLILGFK----RS-
------VDINL-WSKITEQLYKDGRYCQASSGPT-ETVGYFLYNLIDSMSDSEVQAKEEH
LRQYFHQLKKMNIQIPESIYRGIHKRLHRLHVPELIKGVALLADRETSRFS----KILGE
NLSDIEQKLENLKTEKQPIGDVLKQLILKLCSEENMQKALEIKTKYESD-MVVGG

PF01535 // ENSGT00390000016775_0_Domain_11 (836, 855)

YAALI
NLCCRHDNVEEAMN

ENSGT00390000016775_0_Linker_11_12 (855, 886)

L-------------KQQVDRIDSSITLSPGK

PF01535 // ENSGT00390000016775_0_Domain_12 (886, 914)

YVSLVKALMKHGRVQ
DAINILKEIKEKNIFLKDRT--FFSHIIHEAALLGEVEPVKQLHETILTLGLAKPNVTLC
SPLVTLHLEK-DDIPAALEVTLDC---FKKYGIMPMIHEVLCKMI-EKGETDLIQKAMDF
VSQEQGEMTMLYDLFFAFMETGN-YKEAKKIIETPGIRARSGKLQWFCEKCISENQVETL
EKLVE-MTQKLFECDRDQMYYHLLILCKENNDWKRADAVWTKIQEENIIPRQKTLRLLGE
ILRNNNQDVPFD----IPMLWYDDSL-EDDP--QQNAFSLPTEITLKNELMSVCHMRNSE
-DAYSMFLEAQKKNVVFPALTYSTLIKLLLASGHL-DEALNVK-NIAETHIKGFTLNDAA
NSLLIITQVRRDYLKDALATLASALNSHQIPSPLSVSRLVQAFASKGDKENVQVVEKLVH
DFRGSLRLSNMLFVNNIAFAEIKNNNLDAAVEYLEP--LYTSAS--PGAEMSSIAYIFRK
VIEEQLEPAIEK----------------------------------------LSIMSERL
ANQFAIYRPVTDLFLEYIYSGRLDDARTLLQRCGAIAEQTPILLGFFLRYSKIQGKT---
-QILKSLLEIIPDLTVNPE

PF01535 // ENSGT00390000016775_0_Domain_20 (1520, 1549)

VYGLLMRSYGLDKDVASAKALYEEMKAKNIEMDNVFLKHYA
ILLKKAGETLPFPEPPESFKFYIEQLKKEGQVSL----------

------------------------------------------------------------
---------MAALLRPARWLLRAGAAPRLPLSLRL-------LAGGLS--RPHAVPCLPA
GRGGPLAGGLLNQARRYAI-AVEKKNYLQEEPA------SSHRRTASQFDWALMRLDNSV
RRTGRIPKTLLQKVFDSTCN-SGSPGGNQALLLLRSCGSLLPELQLSERTEFAHRIWDKL
QKLGTVYDVSHYNALLKVYLQNEYKFSPTDFLAKMEEANIQPNR

PF01535 // ENSGT00390000016775_0_Domain_6 (285, 314)

VTYQRLIAAYCNVGDI
EGASKILGFMKTK

ENSGT00390000016775_0_Linker_6_8 (314, 321)

DLPVTEA

PF01535 // ENSGT00390000016775_0_Domain_8 (321, 351)

VFSALVTGHARAGDIENAENIFSV-MKEAG

ENSGT00390000016775_0_Linker_8_7 (351, 357)

IEPGPD

PF01535 // ENSGT00390000016775_0_Domain_7 (357, 384)

TYLA
LLNAYAEKGDIDHVKQTLEKVEKSDLYLMDRDLLQIIFSFSKAGYSQHVPEILEKITYER
RYIPDAMNLILLLVTEKLEDTAFQILLACPVSRE-------GSLSDFGSFFLRHCVTMDT
PAEKLKDYCKKLKESQMHASPLQFTLQSALLANKTDLAKALMKALKEEGF-PVRTHYFWP
LLVGRQKEKDVQGVIEVLKAMREMGVSPDQETYINYVFPSFDSVRSARAVLQENGCLHES
N--VFSQAELRSEAINGN----LAFILSFLESNTQ-PLSFS-SLRGSLSLGFR----RS-
------MDINL-WSKITELLYKDGRYCQEPPGPT-EAVGYFLYNLIDSMSDSEVQAKEER
LRQYFHQLKEMNVKIPENIYRGIRNLLDSYHVPELIKDVNILVEREKIDSR----KTVQL
PSSVLESTLEKLKAANQPIGDVLKQLILALCSEENMQKALELKAKYESD-MVVGG

PF01535 // ENSGT00390000016775_0_Domain_11 (836, 871)

YAALI
NLCCRHDNAEDALNL-------------KQ

ENSGT00390000016775_0_Linker_11_12 (871, 888)

EFDRLDSSAVLDTGKYV

PF01535 // ENSGT00390000016775_0_Domain_12 (888, 914)

GLVKVLGKHGKLQ
DAINILKEMKEKD

ENSGT00390000016775_0_Linker_12_13 (914, 1100)

VLIKDATVLSFFHILNGAALRGETETVKRLHEAIMTLGLAKPSSALS
SPLVTLYLEK-DDLGAALEVAIDC---YEKYKVLPRIHDILCKLI-EKGETDLIQKAMNF
VSQEQGEMTMLYDLFFAFLQTGN-YKEAKKIIETPGIRARPTRLQWFCERCISSNQVEVL
EKLVE-LTQKLFECDRDQL

PF01535 // ENSGT00390000016775_0_Domain_13 (1100, 1128)

YYSLLKLYKVNGDWQKADAVWNKMQEENIIPRAKTLRLLAE
ILRNSNQEVPFD----VPELWYEDEK-HSLN---F-SSPSHTESNIQKDLLNACQQKRSK
-DAYTIFLKAQKQNIIFNSETYSNLIKLLLEKDSF-IEAVQVK-EFAETHIKGFTLNDAA
NSLLIITQVRRDYLKEALTTLKAALDLEQIPSRLAVTRLIQACALKGDVESIQAIQKMVD
GLEHSIGLSNMVFINNIALAQIKKNHINCRGKNSNKIDYLASEWRIITVKYISRSTLTRN
LIMQNLLSVTFS----------------------------------------VSIMAERL
ANQFAVYKPVTDLFLQLLESGKVDDARALLQRCGAIAEQTSIFLVFCMRSSQRPGKA---
-STLKSLLELIPELIEKEEAYTSVMKSYVSDKDVVSAKALYEHLMARNVKLNNLFLKRYA
FLLKNAGEPVPFTEPPESFEFYAKQLKESRENPL----------

------------------------------------------------------------
---------MAALLRSARWLLRATAAPYLPLSLRL-------LAGGPG--RPHAALCLRA
ARARPVAGGLLSQARLHSI-AAEKKNDLQEEPT------SSHRRNASQFDWALMRLDNSV
RRTGRIPKTLLQKVFDNTCH-SGSPGGNQALLLLRSCGSLLPELKLSERTEFAHKIWDEL
QKLGTVYDVSHYNALLKVYLQNEHKFSPTDFLAKMEKGNVQPNR

PF01535 // ENSGT00390000016775_0_Domain_6 (285, 314)

VTYQRLIAAYCNMGDI
EGASTILGFMKTK

ENSGT00390000016775_0_Linker_6_8 (314, 321)

DLPVTEA

PF01535 // ENSGT00390000016775_0_Domain_8 (321, 351)

VFSALVTGHARSGDMENAENILTV-MKEAG

ENSGT00390000016775_0_Linker_8_7 (351, 357)

IEPGPD

PF01535 // ENSGT00390000016775_0_Domain_7 (357, 384)

TYLA
LLNAYAEKGDIDHVKQTLEKVEKSDLYLMDRDLLQIILSFSKAGYPQYVPEILEKITYER
RYIPDTMNLILLLVTEKLEDTALQILLACPISRE-------SSLNDFGSFFLRHCVTVNT
PPEQLRDYCKKLKEAQLHTSPLQFTLQCALVAQKFDLAKVLMKALKEEGF-PIRTHYFWP
LLVGHQKEKNVQGIVEVLKGMHEMGVTPDQETYVNYVFPSFDSIESVRAVLQENGCPHDD
N--VFSQAELRSKAVNGN----LDYILSFMESNTL-PFSFA-SLRGSLILGFR----RS-
------MNINL-WSKITELLYKDGRYCQEPPGPT-EAVGYFLYNLIDSMSDSEVQAKEEH
LRQYFHQLKEMNVKIPENIYRGIRNLLDSYHVPELIKDVNILVEREK--TDSRKISTSQP
SSSDLESKLEKLKAENQPIGDILKQLILMLCSEENMQKALELKAKYESD-MVVGG

PF01535 // ENSGT00390000016775_0_Domain_11 (836, 871)

YAALI
NLCCRHDNAEDALNL-------------KR

ENSGT00390000016775_0_Linker_11_12 (871, 889)

EFDRLDSSAVLDTGKYVR

PF01535 // ENSGT00390000016775_0_Domain_12 (889, 914)

LVKVLGKHGKLQ
DAINILKEMKEKD

ENSGT00390000016775_0_Linker_12_13 (914, 1100)

VLIKDATVLSFFHILNGAALRGETETVKQLHEAIVTLGLAKPSTTLS
SPLVTLYLEK-DDLPAALESTIDC---YEKYKILPRIHDVLCKLI-EKGETELIQKAMDF
VSQEQGEMTMLYDLFFAFLQTGN-YKEAKKIIETPGIRARPTRLQWFCDRCIANNQVETL
EKLVE-LTQKLFECDRDQL

PF01535 // ENSGT00390000016775_0_Domain_13 (1100, 1128)

YYSLLKLYKVNGDWQKADAVWNKMQEENIIPREKTLRLLAE
ILRNNNQDVPFD----VPELWYEEEK-DSPT-----SLPSPVEVNLQKELLNACRTRRNK
-DAFNIFLTAKKQNIVFDNEAYARLINLLLMKDNS-TQAMQVK-DFAETHIKGFTLNDAA
NSLLIITQVRRDYLKDALTTLKTALDLDQIPSRLAVTRLIQACALKGDTESVQDIQKLVN
GLEDSIGLSRMVFINNIALAQIKNNNIDVAIESIEN--MLTSENQTVDPQYFGLAYLFRK
VIEGQLEPALEK----------------------------------------ISIMVERL
ANQFAVYKPVTDLFLQLVDSGKVDDARALLQRCGAIAEQIPILLVFCIRNSQRSGKA---
-PVMKSLLELIPELIDKEEAYSCLMKSYVFDSDVASAKALYESLTAKNVKLNDLFLKRYA
VLLKNAGESVPFTEPPESFEFYAKQLKESKETHL----------

------------------------------------------------------------
---------MAALLRPARWFLGAGATLRLPLSLRL-------PSGGPG--RT-------A
ARSRPVAGELLSQARLYAI-AAERKKDLQEELV-------SPRRSSSQFDWALMRLENSV
RRTGRITKGLLQKVFESTCH-SGSPSGSQALLLLRSCGSLLPELSLAERTEFAH

PF13812 // ENSGT00390000016775_0_Domain_5 (235, 295)

KIWDKL
QKLGAVYDVSHYNALLKVYLQNEHKFSPTDFLAKMEEANIQPNRVTYQRLIAAY

ENSGT00390000016775_0_Linker_5_7 (295, 309)

CDSGDI
EGASKILG

PF17177 // ENSGT00390000016775_0_Domain_7 (309, 418)

FMKAKDLPVTEAVFSALVTGHARAGDMENAENILTV-MKEAGIDPGSDTYLA
LLKAYAEKGDIDHVKQTLEKVEKSDHYLMDRDLLQIIVSFSKAGYPQYVSEILEKITYER
RYIPDAMNLILLLVTEKLEDIALQILLACPVSKE-------ENENNFGGFFLQHCISMGT
PADKLIGYCKQLKEVKMHCAPLQSALHSALLAHRTDLAKALMEALKEEGF-PVRTHYFWP
LLVQHQKEKNVQGIIDLLKVMHEMGVDPDQETYVNYVFPCFDNVKSVRGILQENGCLPES
N--TFSQAEVRIEALNGN----LDSILSFLESNTV-PFSFN-SLRGSLILGFK----RS-
------MNIDL-WSKITELLYKDGRYCQEPPGPT-EAVGYFLYNLIDSMSDSEVQAKEEH
LRQYFHQLKEMNVKIPENIYRGIRNLLDSYQVPELIKDVNVLVERGKIDSR----KTSQL
MSSDLESTLENLKAENQPVGDTLKQLILVLCSEENMQKALEVKAKYESD-MVIGG

PF01535 // ENSGT00390000016775_0_Domain_11 (836, 871)

YAALI
NLCCRHDNAEDALNL-------------KQ

ENSGT00390000016775_0_Linker_11_12 (871, 888)

EFDRLDPSAVLDTNKYL

PF01535 // ENSGT00390000016775_0_Domain_12 (888, 914)

GLVKVLGKHGKLP
DAINILKEMKEKDVLIKDTTVLSFFHILNGAALRGDTEAVKQLHEAIVNLGLAKPSIHIS
VPLVTVHLEK-DDLPAALEASLDC---YKKYKVLPRMHDVLCKLI-EKGETDLIQKAMDF
VSQEQGEMTMLYDLFFAFLQTGN-YKEARKIIETPGIRARPTRLQWFCDRCITSNQVETL
EKLVE-LTQKLFECDRDQMYYSLLRLHKLNNDWQRADAVWNKMQEENIIPREKTLRLLAE
ILRNGNQEVPFD----VPELWYEDEK-LSLS---P--APSAEETDVEKSVLKACRLRRSK
-DAYNSFLNAKRQNIVFNSETYSTLIKLLLAKDDL-TQAMQVK-DFAETHIKGFTLNDAA
NSLLIITQVRRDYLKVALTTLKRALDLEQIPSRLSVTRLIQAFAMKGDVQSIEAIQKMVN
GLD-SIGLSHMVFINNLALAQMKNNNIDAAIENIES--MLTSETQPVESQYFGLTYLFRK
VIEEQIEPALEK----------------------------------------LSIMAERL
ANQFAVYKPVTDLFLQLLDSGRAGDARALLQRCGAIAEQTSILLVFCLRTSQQPNKA---
-PVLKSLLELIPELKEQEQAYGCAMKSYVLDKDVTSAKALFEHLSSKNRKLDDLFLKRYA
VLLKSAGEPVPFTEPPESFEFYAKQLKEAKESSS----------

------------------------------------------------------------
---------MAALLRPARWLLGAAATPRLPLTLRL-------LAGGPG--RLFSVSRVAA
AGGKPPAGELLSQARLYAI-AAE-KRDLQEEPA-------PMRRNSSQFDWALMRLNNSV
RRTGRITKGLLQKVFESTCR-SESPGGNQALLLLRSCGSLLPELSLAERTEFAHKIWDKL
EKLGTVYDVSHYNALLKVYLQNEYKFSPTDFLAKMERANIQPNRVTYQRLIAAYCNVGDI
EGASKILGF

PF17177 // ENSGT00390000016775_0_Domain_7 (310, 418)

MKTKDLPITEAVFSALVTGHARAGDMENAENILTV-MKEAGIEPGPDTYLA
LLNAYAEKGDIDHVKQTLENVEKLDHYLTDRDLLHIIVTFSKAGYPQYVSQILEKVTYER
RYIPDAMNLILLLVTEKLEDTAFQILLALPMSKE-------ESMNTFGSFFLRHCVTMNT
PTEKLIDYCKKLKEAKLHSSPLQFTLQCALLNNKTALAKAVMQALKEEGF-PIRPHYFWP
LLVEHKKTKNLEGIMDILKIMTELGVDPDQDTYVNYVFPCFDNVASFRAALQENGCLPKS
N--KFAQAEMRSEAMNGN----LQNILSLLESNEL-PLSMN-SFRNSLILGFR----RS-
------MDIDL-WSKITELLYKDRRYCREPSAAT-EAVGYFLYHLIDSMSDSEVQAKEEH
LRQYFHQLKKMNVKVPENIYKGIRNLLDGYHVPELIKDVKVLVDKEKVDSW----KTSQL
TPSDLESKLEKLQADNQPIGDVLKQLILLLCSEENMEKALEVKAKYESD-MVIGG

PF01535 // ENSGT00390000016775_0_Domain_11 (836, 871)

YAALI
NLCCRHDNAEDALNL-------------KQ

ENSGT00390000016775_0_Linker_11_12 (871, 889)

EFDRLYPSAVLDTVKYIR

PF01535 // ENSGT00390000016775_0_Domain_12 (889, 914)

LIKVLGKHGKLQ
DAIKILKEMKEKDVAIQDSTVMSFFHVLNGAALRGEIETVKQLHEAIVTLGLAKPSTSIS
IPLVTMYLEK-DDLPAALEACIDC---HEKYKVLPRIHDVLCKLI-EKGETDLIQKAMDF
VSHEQGEMTMLYDLFFAFLQTGN-YKEAKKIIETPGIRARPARLQWFCDRCITANQVETL
EKLVE-LTEKLFECDRDQMYYNLLRLHKMNSDWQRADTVWNKMQEENVIPRERTLQLLAE
ILKTSNQEVPFD----VPELWFEDDS-SSLS---S-SSPPAVETITEKMLLDTCNRRKNK
-DAYNIFLKAQRQNIVFSSKTYSTLISLLLRRDSF-TEAMQVK-DFAETHIKGFTLNDAA
NSLLIIAQVRRDYLKVALETLKAALALQQAPSQVAITRLIQACALKGDLESIEAIREMVN
GLD-KIRLSKMVFINNTALAQMKNNNIDVAIENIEQ--KLMSENQTIDPKYFDLSYLFRK
VIEEQMETALER----------------------------------------LSIMSERL
ANQFSIYKPVTDLFLQLLDSGKVDEAKALLERCGAIAEQSTVLLVFCRRNCQKPKKA---
-PVLKTLLELIPELRDKEDAYSCSMRSYALDKDVASAKELYEYLTAKNMPIDDLFLKRYA
TLLKEVGEPVPFTEPPESFEFYVKQLKEARENPS----------

------------------------------------------------------------
---MAALLSSAGRLRSLCVRLRPLL---------L-------PP----------------
--APAAARNVIHQARFLTV-VPQREGSVKEEPVSE-----IQNRRSWQFDWALNKLDHSV
RKTGRIPKTLLLKVFQETCRE-GCPGSNQTLLLLRSCGALLPEVLSSERTELAHM

PF13812 // ENSGT00390000016775_0_Domain_5 (236, 296)

IWDKM
KELGAVYDTSHYNALLKVYLQNEHKFSPTEFLARMEEANVQPNRVTYQRLIAAYC

ENSGT00390000016775_0_Linker_5_7 (296, 310)

NEGDI
EGASKILGF

PF13812 // ENSGT00390000016775_0_Domain_7 (310, 366)

MKSKDLPITEAVFSSLVKGHARSGDIKSAENILSV-MRMAGVEPGPDTYLS
LLNVYAEKGDADSIKKTLEEVEKTEGYLMDRVLMQVIFSLAKAGYPQYIEDIKERMRFEKELIPDMMNLCLTLITHGFEDISFRILKSYNHLSR--------ENVDQGSFFLQHCVNRNMPMSKLKQFCNELKEAKMHSAPLIFILRCALETNKSGLAIDVMRAMKEEGL-PLRPHYCWPLLVGFQKEKNLKGVFEVLKVMHELGVELNAETYTDYVFKNFADIETACAQMKENNCLFETD--GLFVAQIRHEAGHGR----LKNVVSLLSSASTPSIDFR-QFRNSLILGFR----SS-------NDVQL-WSQITELLYKDERYCLTPPGPT-EAVGYFLYHLIDSMSDSEVQAKEERLRQYFHQLKKMNVVIPATYCSGICRLLDSSQVPELIKDVRSLSPK-KFMSTEDIPDSAKSDVSALEKKLEKRKAENQPITDVLKQFIYALCEEENMQKALEVKAKYEPD-MVVGGYAALINLCCRHDNVEEAMNL-------------KEKVFPKSSPVALDSGKYIALVEVLAKHGRLEDAINVLREMKEKDVPISERAVASFFRLLNAAAIRGEVETVNRLHETIVNLGLAE-TAALYSPLITVHLEK-DDMPAVLEALMDC---YKKHGKILQLHNIYCRLI-EKGDTELLRKVSDFISSEYGDMMALYDLFFAFLQTGK-YKEARKVIETPGLRAHSGRLQWFAKRCISGNQMETLEHLVE-LTQNVFECDRDEMYYYLLQLCDNNSDWRRAEAVWTKIQEENVVPREKTLRLLADIFEKNGQVVPFE----VPKT-----RQEEMRSPGSSDIEERKI-------RMLCKKNSAR-EAYNVFLKNQGKSD-YQYRTYDTLIKALLSLDCI-EEAMKVK-HTAETHIKGFTLNSAASSLLIISQVRRDYLKDAVAAFQGMLDSGLLPSRPAVIALTQALAMKGDLRNLKALENMVESITESIGLSPSLISNAIALAHTNNNDLDAAVEYLEP--LLISGAQNPDQPVKNISFLLRKVSEKGLEPALEK----------------------------------------FGVMAERLANQFGIYRPVTDLFLQYVSADRVDDARSLLQRCGGLVEEKRAFVNYMTKAASKPGQA----RKIEKLLELIPDSIDLETAYRHLIRCYELDGDVASVKAVYEKTKEKN

PF13812 // ENSGT00390000016775_0_Domain_8 (310, 366)

MKSKDLPITEAVFSSLVKGHARSGDIKSAENILSV-MRMAGVEPGPDTYLSLLNVYAEKGDADSIKKTLEEVEKTEGYLMDRVLMQVIFSLAKAGYPQYIEDIKERMRFEK
ELIPDMMNLCLTLITHGFEDISFRILKSYNHLSR--------ENVDQGSFFLQHCVNRNM
PMSKLKQFCNELKEAKMHSAPLIFILRCALETNKSGLAIDVMRAMKEEGL-PLRPHYCWP
LLVGFQKEKNLKGVFEVLKVMHELGVELNAETYTDYVFKNFADIETACAQMKENNCLFET
D--GLFVAQIRHEAGHGR----LKNVVSLLSSASTPSIDFR-QFRNSLILGFR----SS-
------NDVQL-WSQITELLYKDERYCLTPPGPT-EAVGYFLYHLIDSMSDSEVQAKEER
LRQYFHQLKKMNVVIPATYCSGICRLLDSSQVPELIKDVRSLSPK-KFMSTEDIPDSAKS
DVSALEKKLEKRKAENQPITDVLKQFIYALCEEENMQKALEVKAKYEPD-MVVGG

PF01535 // ENSGT00390000016775_0_Domain_11 (836, 855)

YAALI
NLCCRHDNVEEAMN

ENSGT00390000016775_0_Linker_11_12 (855, 886)

L-------------KEKVFPKSSPVALDSGK

PF01535 // ENSGT00390000016775_0_Domain_12 (886, 914)

YIALVEVLAKHGRLE
DAINVLREMKEKDVPISERAVASFFRLLNAAAIRGEVETVNRLHETIVNLGLAE-TAALY
SPLITVHLEK-DDMPAVLEALMDC---YKKHGKILQLHNIYCRLI-EKGDTELLRKVSDF
ISSEYGDMMALYDLFFAFLQTGK-YKEARKVIETPGLRAHSGRLQWFAKRCISGNQMETL
EHLVE-LTQNVFECDRDEMYYYLLQLCDNNSDWRRAEAVWTKIQEENVVPREKTLRLLAD
IFEKNGQVVPFE----VPKT-----RQEEMRSPGSSDIEERKI-------RMLCKKNSAR
-EAYNVFLKNQGKSD-YQYRTYDTLIKALLSLDCI-EEAMKVK-HTAETHIKGFTLNSAA
SSLLIISQVRRDYLKDAVAAFQGMLDSGLLPSRPAVIALTQALAMKGDLRNLKALENMVE
SITESIGLSPSLISNAIALAHTNNNDLDAAVEYLEP--LLISGAQNPDQPVKNISFLLRK
VSEKGLEPALEK----------------------------------------FGVMAERL
ANQFGIYRPVTDLFLQYVSADRVDDARSLLQRCGGLVEEKRAFVNYMTKAASKPGQA---
-RKIEKLLELIPDSIDLETAYRHLIRCYELDGDVASVKAVYEKTKEKNIQLPELSLKSLA
AFLKKAGEPVPFTEPPESFKFYVEEWRKRRLEAS----------

------------------------------------------------------------
---------MAALLRPARWLLRAAAAPYLPLSLRL-------LAGGPG--RPDAAVCLRA
ARARPVAGGLLSQARLHSI-AAEKKNYLQEEPT------SSHRRNASQFDWALMRLDNSV
RRTGRIPKTLLQKVFDNTCH-SGSPGGNQALLLLRSCGSLLPELKLSERTEFAH

PF13812 // ENSGT00390000016775_0_Domain_5 (235, 296)

KIWDEL
QKLGTVYDVSHYNALLKVYLQNDHKFSPTDFLARMEKGNIQPNRVTYQRLIAAYC

ENSGT00390000016775_0_Linker_5_7 (296, 310)

NMGDI
EGASTILGF

PF17177 // ENSGT00390000016775_0_Domain_7 (310, 418)

MKTKDLPVTEAVFSALVTGHARSGDMENAENILTV-MKEAGIEPGPDTYLA
LLNAYAEKGDIDHVKQTLEKVEKSDLYLMDRDLLQIILSFSKAGYPQYVPEILEKITYER
RYIPDTMNLILLLVTEKLEDTALQILLACPISRE-------SSQNDFGSFFLRHCVTMNT
PAEKLKDYCKKLKEAQLHTSPLQFTLQCALVAQKLDLAKVLMKALKEEGF-PIRTHYFWP
LLVGHQKEKNVQGIVEVLKGMHEIGVTPDQETYVNYVFPCFDSIKSVRAVLQENGCPHDD
N--VFSQAELRSKAVNGN----LDYILSFLESNTL-PFSFS-SLRGSLILGFR----RS-
------MNINL-WSKITELLYKDGRYCQEPPGPT-EAVGYFLYNLIDSMSDSEVQAKEER
LRQYFHQLKEMNVKIPENIYRGIRNLLDSYHVPELIKDVNILVEREK--TDSRK-----P
SSSDLESKLEKLKAENQPIGDILKQLIVMLCSEENMQKALELKAKYESD-MVVGG

PF01535 // ENSGT00390000016775_0_Domain_11 (836, 871)

YAALI
NLCCRHDNAEDALNL-------------KR

ENSGT00390000016775_0_Linker_11_12 (871, 888)

EFDRLDSSAVLDTGKYV

PF01535 // ENSGT00390000016775_0_Domain_12 (888, 914)

RLVKVLGKHGKLQ
DAINILKEMKEKD

ENSGT00390000016775_0_Linker_12_13 (914, 1100)

VPVKDATVLSFFHILNGAALRGETETVKQLHEAIVTLGLAKPSTALS
SPLVTLYLEK-DDLPAALESTIDC---YEKYKILPRIHDVLCKLI-EKGETELIQKAMDF
VSQEQGEMTMLYDLFFAFLQTGN-YKEAKKIIETPGIRARPTRLQWFCDRCIANNQVETL
EKLVE-LTQKLFECDRDQL

PF01535 // ENSGT00390000016775_0_Domain_13 (1100, 1128)

YYSLLKLYKVNDDWQKADAVWNKMQEENIIPREKTLRLLAE
ILRNNNQEVPFD----VPELWYEEEK-DCPT-----SLPSPVEVNLQQGLLNACHRRRNK
-DAFNIFLTAKKQNIVFDNETYARLINLLLMKDNS-TQAMQVK-DFAETHIKGFTLNDAA
NSLLIITQVRRDYLKDALTTLKTALDLDQIPSRLAVTRLIQACALKGDTESIHDIQKLVN
GLEDSIGLSRMVFINNIALAQIKNNNIDVAIESIEN--MLTSENQTVDPQYFGLAYLFRK
VIEGQLEPALKK----------------------------------------ISIMAERL
ANQFAVYKPVTDLFLQLVDSGKVNDARALLQRCGAIAEQMPILLVFCIRNCQRPGKA---
-PVMKSLLELIPELIDKEEAYTCLMKSYVFDNDVTSAKALYESLTAKNVKLNDLFLKRYA
VLLKNAGESVPFTEPPESFEFYAKQLKESKETHL----------

------------------------------------------------------------
---------MAALLRPARWLLGAAAAPRLPLSLRL-------PAGGPG--RLSSVVRVAA
VGSRPAAGELLSQARLYAI-VAE-KRDLQEEPA-------PVRKSGSQFDWALMRLENSV
RRTGRITKGLLQRVFESTCR-SGSPGSNQALLLLRSCGSLLPELSLAERTEFAHKIWDKL
QQLGVVYDVSHYNALLKVYLQNEYKFSPTDF

PF13812 // ENSGT00390000016775_0_Domain_6 (272, 315)

LAKMEGANIQPNRVTYQRLIAAYCNVGDI
EGASKILGFMKTKD

ENSGT00390000016775_0_Linker_6_7 (315, 322)

LPITEAV

PF13812 // ENSGT00390000016775_0_Domain_7 (322, 365)

FSALVTGHSRAGDMESAENILTV-MKQAGIDPGPDTYLA
LLNAHAERGDIGQVKQILEKVEKSDHYFMDRDFLQVIVSFSKAGYPQYVSDMLEKVTYERRSIPDAMNLILLLATEKLEDTAFQVLLALPLSKD-------ESSNNFGSFFLRHCVAMDTPPEKLIDYCRRLRDAKLHSSSLHFTLHCALQANRTALAKAVMEALREEGS-PIRPHYFWPLLAGHQKTKNVQGIIDILKIMNEMGVDPDQETYINYVFPCFDNAQAVRAALQENECLLASS--TFAQAEVKNEAIKGN----LQNILSFLESNTL-PFSFS-SLRSSLILGFR----RS-------MNIDL-WSKITELLYKDGRYCSKPPGPS-EAVGYFLYNLIDSMSDSEVQAKEERLRQYFHQLQEMNVKVPENIYKGICNLLNTYHVPELIKDIKLLVDREKVDSQ----KTSQVTSSDLESRLEKLKAEGQPVGAVLKQLLLLLCSEENMQKALEVKAKYESD-MVIGGYAALINLCCRHDNAEDAWNL-------------KQEVDRLDPSAILDTAKYVALVKVLGKHSRLQDAINILKEMKEKDVVIKDATVLSFFHILNGAALRGEIETVKQLHEAIVTLGLAKPSSNISFPLVTVHLEK-DDLPAALEASITC---HKKYKVLPRIHDVLCKLV-EKGETDLIQKAMDFVSQEQGEMTMLYDLFFAFLQTGN-YKEAKKIIETPGIRARPARLQWFCDRCIATNQVETLEKMVE-LTEKLFECDRDQMYYNLLKLYKMSSDWQRADAVWNKMQEENIIPRERTLRLLAEILKTGNQEVPFD----VPELWFGDDR-PSLS---P-SSSSAGEAAAEKTLLSNCRLKKSK-DAYNIFLKAEKQNVVFSSETYSTLIGLLLSQDDF-TQALHVK-DFAETHIKGFTLNDAANSLLIIRQVRRDYLKAALATLRAALDLKQVPSQIAVTRLIQALALKGDVESIEAIQKMVAGLD-TIGLSRMVFINNIALAQMKNNKLDAAIENIEH--LLASENQAIEPQFFGLSYLFRKVIEEQMEPALEK----------------------------------------LSIMSERMANQFALYKPVTDLFLQLVDSGKVDEARALLERCGAIAEQSSVLSVFCQRTAQKPKKA----PVLKTLLELIPELRENDKVYSCSMKSYALDKDVASAKALYEYLTAKNLKLNDLFLKRYAS

PF13812 // ENSGT00390000016775_0_Domain_8 (322, 365)

FSALVTGHSRAGDMESAENILTV-MKQAGIDPGPDTYLALLNAHAERGDIGQVKQILEKVEKSDHYFMDRDFLQVIVSFSKAGYPQYVSDMLEKVTYER
RSIPDAMNLILLLATEKLEDTAFQVLLALPLSKD-------ESSNNFGSFFLRHCVAMDT
PPEKLIDYCRRLRDAKLHSSSLHFTLHCALQANRTALAKAVMEALREEGS-PIRPHYFWP
LLAGHQKTKNVQGIIDILKIMNEMGVDPDQETYINYVFPCFDNAQAVRAALQENECLLAS
S--TFAQAEVKNEAIKGN----LQNILSFLESNTL-PFSFS-SLRSSLILGFR----RS-
------MNIDL-WSKITELLYKDGRYCSKPPGPS-EAVGYFLYNLIDSMSDSEVQAKEER
LRQYFHQLQEMNVKVPENIYKGICNLLNTYHVPELIKDIKLLVDREKVDSQ----KTSQV
TSSDLESRLEKLKAEGQPVGAVLKQLLLLLCSEENMQKALEVKAKYESD-MVIGGYAALI
NLCCRHDNAEDAWNL-------------KQEVDRLDPSAILDTAK

PF01535 // ENSGT00390000016775_0_Domain_12 (886, 914)

YVALVKVLGKHSRLQ
DAINILKEMKEKDVVIKDATVLSFFHILNGAALRGEIETVKQLHEAIVTLGLAKPSSNIS
FPLVTVHLEK-DDLPAALEASITC---HKKYKVLPRIHDVLCKLV-EKGETDLIQKAMDF
VSQEQGEMTMLYDLFFAFLQTGN-YKEAKKIIETPGIRARPARLQWFCDRCIATNQVETL
EKMVE-LTEKLFECDRDQMYYNLLKLYKMSSDWQRADAVWNKMQEENIIPRERTLRLLAE
ILKTGNQEVPFD----VPELWFGDDR-PSLS---P-SSSSAGEAAAEKTLLSNCRLKKSK
-DAYNIFLKAEKQNVVFSSETYSTLIGLLLSQDDF-TQALHVK-DFAETHIKGFTLNDAA
NSLLIIRQVRRDYLKAALATLRAALDLKQVPSQIAVTRLIQALALKGDVESIEAIQKMVA
GLD-TIGLSRMVFINNIALAQMKNNKLDAAIENIEH--LLASENQAIEPQFFGLSYLFRK
VIEEQMEPALEK----------------------------------------LSIMSERM
ANQFALYKPVTDLFLQLVDSGKVDEARALLERCGAIAEQSSVLSVFCQRTAQKPKKA---
-PVLKTLLELIPELRENDKVYSCSMKSYALDKDVASAKALYEYLTAKNLKLNDLFLKRYA
SLLKDVGEPVPFPEPPESFAFYIKQLKEASESPS----------

------------------------------------------------------------
------------------------------------------------------------
--------QLLSQTRLYAI-AAEKKNYLQEEF-------ISYRRNASQFDWALMRLDNSV
RRTGRIPKTLLQKVFDNTRH-SGSPGGNQALLLL

PF01535 // ENSGT00390000016775_0_Domain_2 (215, 249)

RSCGSLLPELKLSERTEFAHRIWDEL
QKLGTVYD

ENSGT00390000016775_0_Linker_2_5 (249, 250)

V

PF01535 // ENSGT00390000016775_0_Domain_5 (250, 284)

SHYNALLKVYLQNEYKFSPTDFLAKMEKANIQPNRVTYQRLIAAYCNVGDI
EGASKILGFMKTKDLPVTE

PF01535 // ENSGT00390000016775_0_Domain_8 (320, 355)

AVFSALVTGHARAGDMENAENILTV-MKEAGIEPG

ENSGT00390000016775_0_Linker_8_7 (355, 356)

P

PF01535 // ENSGT00390000016775_0_Domain_7 (356, 390)

DTYLA
LLNAYAEKGDIDRVKQTLEKVEKSDLYLMDRDLLQIILSFSKAGYPQYISEILEKITYER
RYIPDMMNLILLLVTEKLEDTALQILLACPVSRE-------DSPSDFGSFFLRHCVTMNT
PAEKIKDYCQKLKEAPLHASPFQFTLQCALLANNLDLAKTLMKALKEEGF-PIRTHYFWP
LLVGHQKKKNVQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXEHGCLHEN
D--IFSQAELRSEAVNGN----LDYVLSFLESNTL-PLSLT-SFRGSLILGFR----RC-
------TSISL-WSKITELLYKDGRYCQEPPGPT-EAVGYFLYNLIDSMSDSEVQAKEER
LRQYFHQLKEMNVKIPENIYRGIRNLLDSYHVPELIKDVNMLVEREKTDSQ----KTTQF
TSSHLESKLEQLKAKNQPIGDVLKQLILMLCSEENMQKALELKAKYESD-MVV

PF01535 // ENSGT00390000016775_0_Domain_11 (834, 881)

GGYASLI
NLCCRHDNAEDALNL-------------KREFDRLDSSAV

ENSGT00390000016775_0_Linker_11_12 (881, 884)

LDT

PF01535 // ENSGT00390000016775_0_Domain_12 (884, 918)

GKYVALVRVLGKHGKLQ
DAINILKEMKEKDVLIK

ENSGT00390000016775_0_Linker_12_13 (918, 1098)

DATVLSFFHILNGAALRGETETVKQLHEAIVTLGLAKPTTTLT
SPLVTLYLEK-DDLPTALEVTLDC---YEKYKVLPRIHDVLCKLI-EKGETDLIQKAMDF
VSQEQGEMTMLYDLFFAFLQTGN-YKEAKKIIETPGIRARSARLQWFCDRCIASNQVETL
EKLVE-LTQKLFECDRD

PF01535 // ENSGT00390000016775_0_Domain_13 (1098, 1132)

QLYYSLLKLYKASGDWQRADAVWNKMQEENIIPRGKTLRLLAE
ILRNSNQEVPFD----VPELWYEDEN-LSVT-----SSPTPVDDSLQKDLLIACQRKRNK
-XXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXX-XXXXXXXXXXAETHIKGFTLNDAA
NSLLIITQVRRDYLKDALTTLKTTLDLEQVPSRVAVTRLIQACALKGDTESVQAIQKLVN
GLEDSIGLR--MFINXXXXXXXXXNNTDAAIENIEN--MLTSGTQAMELQYFGLAYLFRK
VIEEQLEPALEK----------------------------------------LSIMAERL
ANQFAVYKPVTDLFLQLVDSGKVEDARALLQRCGAIAEQIPIILVFCIRTSRKLGKA---
-PAMKSLLELIPELIEKE

PF01535 // ENSGT00390000016775_0_Domain_20 (1519, 1553)

EAYTSIMKSYVLDNDVASAKALYENLTAKDVKLNDMFLKRYA
VLLKNAGESVPFTEPPESFEFYAKQLKELKENPL----------

------------------------------------------------------------
---------MAALLRPARWLLAAGASRRLPLYLRL-------FAGGPG--RPSSVSRLTA
ADVRPAAGVLPSQARLYTI-VAE-KKDLSEEPP-------SLKRNSSQFDWALMRLDNSV
RRTGRITKKLLQRVFESTCR-SGSPGGNQALLLLRSCGSLLPELSLTERTEFAHK

PF13812 // ENSGT00390000016775_0_Domain_5 (236, 296)

IWNKL
QKLGTIYDVSHYNALLKVYLQNEHKFSPTDFLTKMEEAHIQPNRVTYQRLIAAYC

ENSGT00390000016775_0_Linker_5_7 (296, 309)

NTGDM
EGASKILG

PF17177 // ENSGT00390000016775_0_Domain_7 (309, 418)

FMKTKDLPITEAVFSALVTGHARAGDMENAENILTV-MKDAGIEPGPDTYLA
LLNAYAEKGNIDHVKQILENVEKSDHCLMDRDLLQIIVSFSKAGYPQYVSEILDKVTYER
RYIPDAMNLILLLVTKKLEDTAFQILLALPISNE-------DNENDFGSFFLQHCVTMDT
PAEKLIDYCKKLKEAKMHSSSLHFTLHCALLANKADLAKALMKVLKEEGF-PIRFHYFWP
LLIAHQKRKDVQGIIDILKIMKEMGVDPNQETYVNYVFPCFDDIKSVRAALQENECLPNS
N--TLYQAEVRSEALNGN----LDSILSLLESNIS-PFPFN-SLRGICICSCLLLLLQC-
------MNF-L-SYQITELLYKDGRYCQEPPGPT-EAVGYFLYNLIDSMSDSEVQAKEEH
LRQYFHQLKKMNIKVSENIFRGIRNLLEGYHVPELIKDVKVLVDTEKIDSR----KTPQL
TSSDLESTLEKLKVGNQPIGDVLKQLILLLCSEENMEKALEVKAKYESD-MVIGGYAALI
HLCCRHDNAEDALNL-------------KQEFDRLDPSAVLDTAKYV

PF01535 // ENSGT00390000016775_0_Domain_12 (888, 914)

GLVKVLGKHGRLQ
DAINILKEMKEKDVLIKDATVLSFFHILNGEALRGETETVKQLHEAIVTLGLAKPTTNIS
FPLVTVHLEK-DDLPAALEASIDL---YQKYKILPRIHDVLCKLI-ERGETDLIQKAMDF
VSQEQGEMTMLYDLFFAFLQTGN-YKEARKIIETPGIRARPTRLQWFCDRCITSNQVETL
EKLVE-LTEKLFECDRDQMYYSLLKLYKVNSDWQRADAAWNKMQEENIIPREKTLRLLAE
ILKSNNQEVPFD----VPELWFEDDR-HSLS---S-SSASTVEADMEKTVLEACRLRKFR
-DAFTMFLEAQKQNVVFNSETYSTLIRLLLSKDNF-TEAMQVK-DFAETHIKGFTLNDAA
NSLLIITQVRRDYLKVALETLKAALDLEHIPSKIAVTRLIQAFALKGDLESIEAIQKMVN
GLS--IGLSSMVFINNIALAQMKNNNIDVAIENIEH--MLTSENRTIEPQYFGLSYLFRK
VIEEQMEPAIEK----------------------------------------LSIMSERL
ANHFALYKPVTDLFLQLVDSGRVDDAKALLQRCGAIAEQTSIFLVFFLRNSQKPKKA---
-PVLKTLLELIPELREKEEVYSSSMKSYVLDKDVASAKVLYDHLTAKNVKLNELFLKRYA
SLLKHAGQPVPFTEPPESFEFYIKQLKEERESPS----------

------------------------------------------------------------
---------MSALLRPARWLLGAAAVPRLPLSLRL-------PAGGPG--RLPSVVRVAA
AGGRPAAGELLSQARLYAI-VAE-KKDLPEEPA-------PVRRSGSQFDWALMRLDNSV
RRTGRITKGLLQKVFESTCR-SGSPGSNQALLLLRSCGSLLPELSLAERTEFAH

PF13812 // ENSGT00390000016775_0_Domain_5 (235, 294)

KIWDKL
QQLGTVYDVSHYNALLKVYLQNEYRFSPTDFLAKMEGANIQPNRVTYQRLIAA

ENSGT00390000016775_0_Linker_5_7 (294, 310)

YCSVGDI
EGASKILGF

PF17177 // ENSGT00390000016775_0_Domain_7 (310, 419)

MKTRDLPITEAVFSALVTGHARAGDMENAENILTV-MKQAGIEPGPDTYLA
LLNAHAEKGDIDHVKQILEKVEKSDHYFMDRDFLQIIVSFSKAGYPQYVSEILEKITYER
RSIPDAMNLILLLVTEKLEDTAFQVLLALPLARD-------ETSSSFGSFFLRHCVTMDT
PAEKLIDYCKRLRDAKVHSSSLQFTLHCALQANKTALAKAVMEALRDEGF-PIRTHYFWP
LLVGHQKTKNVQGIIDILKIMKEMGVDPDQETYINYVFPCFGSVQSARAALQENKCLPKS
T--TFAQAEVRNEAINGN----LQNILSFLESNAL-PFSFN-SLRGSLILGFR----RS-
------MNIDL-WSKITELLYKDDRYCQKPPGPT-EAVGYFLYNLIDSMSDSEVQAKEER
LRQYFHQLREMNVKVSENIYKGICNLLDNYHVPELIKDVKVLVDREKIDSR----KTSQF
TSSDLESTLEKLKAEGHPVGDPLKQLILLLCSEENMQKALEVKAKYESD-MVIGG

PF01535 // ENSGT00390000016775_0_Domain_11 (836, 871)

YAALI
NLCCRHDNAEDALNL-------------KQ

ENSGT00390000016775_0_Linker_11_12 (871, 886)

EFDRLDPSAVLDTAK

PF01535 // ENSGT00390000016775_0_Domain_12 (886, 914)

YVALVKVLGKHGRVQ
DAINILKEMKEKD

ENSGT00390000016775_0_Linker_12_13 (914, 1099)

VVIKDAAVLSFFHILNGAALRGEIETVKQLHEAIVTLGLAKPSSNIS
FPLVTVHLEK-DDLPAALEASIAC---HEKYKVLPRIHDVLCKLI-EKGETDLIQKAMDF
VSQEQGEMSMLYDLFFAFLQTGN-YKEAKKIIETPGIRARPTRLQWFCDRCIANNQVETL
EKLVE-LTEKLFECDRDQ

PF01535 // ENSGT00390000016775_0_Domain_13 (1099, 1127)

MYYNLLKLYKISGDWQRADAVWNKMQEENLIPRERTLRLLAG
ILKTSNQEVPFD----VPELWFGDDR-SSLS---S-SSPSAGDTVTEKMLLSDCRLKKSK
-DAYNIFLKAEKQDVVFSSEAYSTLVGLLLSKDDF-TRAMHVK-DFAETHIKGFTLNGAA
SSLLIIAQVRRDYLKVALETLKAALDLEQVPSELAVTRLIQALALQGDVKSIETIQKMVK
GLD-AIELSRMVFINNIALAQMKNNEIDAAIENIEH--MLASENQTVEHQYFGLSYLFRK
VIEEQMEPALEK----------------------------------------LSIMSERL
ANQFALYKPVTDLFLQLVDSGKVDEARALLERCGAIAEQTSILSVFCLRTSQKPKKA---
-PVLKTLLELIPELRENDRVYSCSMKSYVADKDVASAKALYEHLTAKNMKLDDLFLKRYA
SLLKDVGEPVPFTEPPESFGFYIKQLKEARENPS----------

------------------------------------------------------------
---------MAALLRPARWLLGAAAAPRLPLSLRL-------PAGVPG--RLSSVVRVAA
VGSRPAAGERLSQARLYAI-VAE-KRDLQEEPA-------PVRKNSSQFDWALMRLDNSV
RRTGRITKGLLQRVFESTCS-SGSPGSNQALLLLRSCGSLLPELSLAERTEFAHKIWDKL
QQLGVVYDVSHYNALLKVYLQNEYKFSPTDF

PF13812 // ENSGT00390000016775_0_Domain_6 (272, 315)

LAKMEGANIQPNRVTYQRLIAAYCNVGDI
EGASKILGFMKTKD

ENSGT00390000016775_0_Linker_6_7 (315, 322)

LPITEAV

PF13812 // ENSGT00390000016775_0_Domain_7 (322, 365)

FSALVTGHARAGDMENAENILTV-MKQAGIEPGPDTYLA
LLNAHAERGDIGQVRQILEKVEKSDHYFMDRDFLQVIFSFSKAGYPQYVSEILEKITYERRSIPDAMNLILFLATEKLEDTAFQVLLALPLSKD-------ESSDNFGSFFLRHCVTLDLPPEKLIDYCRRLRDAKLHSSSLQFTLHCALQANRTALAKAVMEALREEGF-PIRPHYFWPLLAGHQKTKNVQGIIDILKIMNKVGVDPDQETYINYVFPCFDSAQSVRAALQENECLLASS--TFAQAEVKNEAINGN----LQNILSFLESNTL-PFSFS-SLRNSLILGFR----RS-------MNIDL-WSKITELLYKDERYCSKPPGPA-EAVGYFLYNLIDSMSDSEVQAKEERLRQYFHQLQEMNVKVPENIYKGICNLLNTYHVPELIKDIKVLVDREKVDSQ----KTSQVTSSDLESTLEKLKAEGQPVGSALKQLLLLLCSEENMQKALEVKAKYESD-MVIGGYAALINLCCRHDNAEDAWNL-------------KQEVDRLDASAILDTAKYVALVKVLGKHSRLQDAINILKEMKEKDVVIKDATVLSFFHILNGAALRGEIETVKQLHEAIVTLGLAKPSSNISFPLVTVHLEK-GDLPAALEASIAC---HKKYKVLPRIHDVLCKLV-EKGETDLIQKAMDFVSQEQGEMTMLYDLFFAFLQTGN-YKEAKKIIETPGIRARPTRLQWFCDRCIASNQVEALEKLVE-LTEKLFECDRDQMYYNLLKLYKISSDWQRADAAWTKMQEENIIPRERTLRLLAEILKTSNQEVPFD----VPELWFGDDR-PSLS---P-SSRSAGEDVTEKTLLSNCKLKKSK-DAYNIFLKAEKQNVVFSSETYSTLIGLLLSKDDF-TQAMHVK-DFAETHIKGFTLNDAANSLLIIRQVRRDYLKGALATLRAALDLKQVPSQIAVTRLIQALALKGDVESIEAIQRMVAGLD-TIGLSKMVFINNIALAQMKNNKLDAAIENIEH--LLASENQAIEPQYFGLSYLFRKVIEEQMEPALEK----------------------------------------LSIMSERMANQFALYKPVTDLFLQLVDSGKVDEARALLERCGAIAEQSSLLSVFCLRTSQKPKKA----PVLKTLLELIPELRDNDKVYSCSMKSYALDKDVASAKALYEYLTAKNLKLDDLFLKRYAA

PF13812 // ENSGT00390000016775_0_Domain_8 (322, 365)

FSALVTGHARAGDMENAENILTV-MKQAGIEPGPDTYLALLNAHAERGDIGQVRQILEKVEKSDHYFMDRDFLQVIFSFSKAGYPQYVSEILEKITYER
RSIPDAMNLILFLATEKLEDTAFQVLLALPLSKD-------ESSDNFGSFFLRHCVTLDL
PPEKLIDYCRRLRDAKLHSSSLQFTLHCALQANRTALAKAVMEALREEGF-PIRPHYFWP
LLAGHQKTKNVQGIIDILKIMNKVGVDPDQETYINYVFPCFDSAQSVRAALQENECLLAS
S--TFAQAEVKNEAINGN----LQNILSFLESNTL-PFSFS-SLRNSLILGFR----RS-
------MNIDL-WSKITELLYKDERYCSKPPGPA-EAVGYFLYNLIDSMSDSEVQAKEER
LRQYFHQLQEMNVKVPENIYKGICNLLNTYHVPELIKDIKVLVDREKVDSQ----KTSQV
TSSDLESTLEKLKAEGQPVGSALKQLLLLLCSEENMQKALEVKAKYESD-MVIGGYAALI
NLCCRHDNAEDAWNL-------------KQEVDRLDASAILDTAK

PF01535 // ENSGT00390000016775_0_Domain_12 (886, 914)

YVALVKVLGKHSRLQ
DAINILKEMKEKDVVIKDATVLSFFHILNGAALRGEIETVKQLHEAIVTLGLAKPSSNIS
FPLVTVHLEK-GDLPAALEASIAC---HKKYKVLPRIHDVLCKLV-EKGETDLIQKAMDF
VSQEQGEMTMLYDLFFAFLQTGN-YKEAKKIIETPGIRARPTRLQWFCDRCIASNQVEAL
EKLVE-LTEKLFECDRDQMYYNLLKLYKISSDWQRADAAWTKMQEENIIPRERTLRLLAE
ILKTSNQEVPFD----VPELWFGDDR-PSLS---P-SSRSAGEDVTEKTLLSNCKLKKSK
-DAYNIFLKAEKQNVVFSSETYSTLIGLLLSKDDF-TQAMHVK-DFAETHIKGFTLNDAA
NSLLIIRQVRRDYLKGALATLRAALDLKQVPSQIAVTRLIQALALKGDVESIEAIQRMVA
GLD-TIGLSKMVFINNIALAQMKNNKLDAAIENIEH--LLASENQAIEPQYFGLSYLFRK
VIEEQMEPALEK----------------------------------------LSIMSERM
ANQFALYKPVTDLFLQLVDSGKVDEARALLERCGAIAEQSSLLSVFCLRTSQKPKKA---
-PVLKTLLELIPELRDNDKVYSCSMKSYALDKDVASAKALYEYLTAKNLKLDDLFLKRYA
ALLKDVGEPVPFPEPPESFAFYIKQLKEARESPS----------

------------------------------------------------------------
-----------SLLRFSCWLLRAGEAPRLPLSLRL------LTGG-PG--RLHAASYLPA
ARAGPVAGGLLSPARLYVI-AAEKKDI-QEES------TFSSRRIANHFDWALMRLDNSV
RRTGRIPKMLLQKVFDDTCRS-GGPGSSHALLLLRSCGSLLPELKLEERTEFAHRIWDKL
QKLGAVYDVSHYNALLKVYLQNEYKFSPTDFLAKMEDANIQPNRVTYQRLIASYCNTGDI
EGASKILG

PF17177 // ENSGT00390000016775_0_Domain_7 (309, 417)

FMKTKDLPVTEAVFSALVTGHARAGDMQNAENILTV-MREAGIEPGPDTYLA
LLNAYAEKGDIDHVKQTLEKVEKSELHLMDRDLFQIIFSFSKAGYPQYVSEILEKVTCER
RYIPDAMNLILLLVTEKLEDVALQILLACPISKE-------DGISDFGSFFLRHCVTMNT
PVEKLTDYCKKLKEIQMHSFPLQFTLHCALLAKKTDLAKALMKAVKEEGF-PIRTHYFWP
LLVGHQKEKNVQGIIEVLKVMQELGVPPDQETYIGYVIPCFNSIKSARAILQENGCLSDS
D--TFSQAELRSEAINGN----LDFVLSFLESNTL-PLSLH-SIRSSLLLGFR----RS-
------MNINL-WSKITELLYKDGRYCQEPPGPT-EAVGYFLYNLIDSMSDSEVQAKEER
LRQYFHQLKEMNVKIPENICRGIRNLLDSYHVPELIKDAYMLVDSENLDSQ----KTMQL
RSSELESRLETLKAEDKPIRDVLKHLILMLCSQENMQKALELKAKYESD-MVISG

PF01535 // ENSGT00390000016775_0_Domain_11 (836, 871)

YAALI
NLCCRHDNAEDALNL-------------KE

ENSGT00390000016775_0_Linker_11_12 (871, 888)

EFDRLDSSAVLDTSKYV

PF01535 // ENSGT00390000016775_0_Domain_12 (888, 914)

GLVRVLAKHGRLQ
DAINILKEMKKKDVPIKDSTVLSFFHILNGAALRGEIETVKQLHEAIVTLGLAKPSTNIS
FPLITVYLEK-DDPSTALDVAIDC---CEKYKILPRMHDILCKLI-EKGETDLIQKAMDF
VSQEQGEMVMLYDLFFAFLQTGN-YKEAKKIIETPGIRARSTRLQWFCDKCIANNQVEAL
EKLVE-LTQKLFECDRDQMYYNLLKLYKMNGDWQRADAVWNKIQEENIIPREKTLRLLAE
ILRDGNQEVPFE----VPE-WYEDEK-HSLNSSLDSSSDSTTEPGFQKYILNACQLKQSK
-EAYGIFLKAKQQNVVFNAETYSDLIKLLLSKEYF-TQAVEVK-AFAETHIKGFTLNDAA
NSLLIITQVRRDYLKEALTTLKTALDQQQTPSGIAVTRLIQALAMKGDVENIEVVQKMVN
GLEDSIGLSKMVFINNTALAQIKNNNIDVAIENIEN--MLTSENPVIELQYFGLAYLFRK
VIEEQLEPAVEK----------------------------------------ISIMAERL
ANQFAIYKPVTDFFLQLVDAGKVDDARALLQRCGAIAEQTSILLVFFLRNAGKQGKV---
-LSYW------------------FRTLFENTKDVTSAKALYEHLTAKNTKLDDLFLKRYA
LLLKNAGESVPFTEPPESFEFYVQQLKELRENSS----------

------------------------------------------------------------
---------MAALLRSARWLLRAGAAPRLPLSLRL------LPWAARA--GCMPASYLPA
ARAGPVAGGLLSPARLYAI-AAKEKDI-QEES------TFSSRKTSNQFDWALMRLDLSV
RRTGRIPKKLLQKVFNDTCRS-GGLGGSHALLLLRSCGSLLPELKVEERTEFAH

PF13812 // ENSGT00390000016775_0_Domain_5 (235, 294)

RIWDTL
QKLGAVYDVSHYNALLKVYLQNEYKFSPTDFLAKMEEANIQPNRVTYQRLIAS

ENSGT00390000016775_0_Linker_5_7 (294, 308)

YCNVGDI
EGASKIL

PF17177 // ENSGT00390000016775_0_Domain_7 (308, 417)

GFMKTKDLPVTEAVFSALVTGHARAGDMENAENILTV-MRDAGIEPGPDTYLA
LLNAYAEKGDIDHVKQTLEKVEKSELHLMDRDLLQIIFSFSKAGYPQYVSEILEKVTCER
RYIPDAMNLILLLVTEKLEDVALQILLACPVSKE-------DGPSVFGSFFLQHCVTMNT
PVEKLTDYCKKLKEVQMHSFPLQFTLHCALLANKTDLAKALMKAVKEEGF-PIRPHYFWP
LLVGRRKEKNVQGIIEILKGMQELGVHPDQETYTDYVIPCFDSVNSARAILQENGCLSDS
D--MFSQAGLRSEAANGN----LDFVLSFLKSNTL-PISLQ-SIRSNCICSCL----LLL
----LQCTNFL-SYQITELLYKDGRYCQEPRGPT-EAVGYFLYNLIDSMSDSEVQAKEEH
LRQYFHQLEKMNVKIPENIYRGIRNLLESYHVPELIKDAHLLVESKNLDFQ----KTVQL
TSSELESTLETLKAENQPIRDVLKQLILVLCSEENMQKALELKAKYESD-MVTGG

PF01535 // ENSGT00390000016775_0_Domain_11 (836, 873)

YAALI
NLCCRHDKVEDALNL-------------KEEL

ENSGT00390000016775_0_Linker_11_12 (873, 888)

DRLDSSAVLDTGKYV

PF01535 // ENSGT00390000016775_0_Domain_12 (888, 914)

GLVRVLAKHGKLQ
DAINILKEMKEKDVLIKDTTALSFFHMLNGAALRGEIETVKQLHEAIVTLGLAEPSTNIS
FPLVTVHLEK-GDLSTALEVAIDC---YEKYKVLPRIHDVLCKLV-ENGETDLIQKAMDF
VSQEQGEMVMLYDLFFAFLQTGN-YKEAKKIIETPGIRARSARLQWFCDRCVANNQVETL
EKLVE-LTQKLFECDRDQMYYNLLKLYKINGDWQRADAVWNKIQEENVIPREKTLRLLAE
ILREGNQEVPFD----VPELWYEDEK-HSLNS----SSASTTEPDFQKDILIACRLNQKK
-GAYDIFLNAKEQNIVFNAETYSNLVKLLMSEDYF-TQAMEVK-AFAETHIKGFTLNDAA
NSRLIITQVRRDYLKEAVTTLKTVLDQQQTPSRLAVTRVVQALAMKGDVENIEVVQKMLN
GLEDSIGLSKMVFINNIALAQIKNNNIDAAIENIEN--MLTSENKVIEPQYFGLAYLFRK
VIEEQLEPAVEK----------------------------------------ISIMAERL
ANQFAIYKPVTDFFLQLVDAGKVDDARALLQRCGAIAEQTPILLLFLLRNSRKQGKV---
-LDTVRALLRSIE----------FNIKAFSEKDVTSAKALYEHLTAKNTKLDDLFLKRYA
SLLKYAGEPVPFIEPPESFEFYAQQLRKLRENSS----------

------------------------------------------------------------
---------MAALLRSSCWLLRAGAAPRLPLSLRL------LTGG-PG--RPHAASYLPA
ARAGPVAGGLLSPARLYVI-AAEKKDI-QEES------TFSSRRIASHFDWALMRLDNSV
RRTGRIPKMLLQKVFDDTCRS-GGPGSSHALLLLRSCGSLLPELKLEERTEFAH

PF13812 // ENSGT00390000016775_0_Domain_5 (235, 296)

RIWDKL
QKLGAVYDVSHYNALLKVYLQNEYKFSPTDFLAKMEEANIQPNRVTYQRLIASYC

ENSGT00390000016775_0_Linker_5_7 (296, 309)

NMGDI
EGASKILG

PF17177 // ENSGT00390000016775_0_Domain_7 (309, 417)

FMKTKDLPVTEAVFSALVTGHARAGDMENAENILTV-MREAGIEPGPDTYLA
LLNAYAEKGDIDHVKQTLEKVEKSELHLMDRDLFQIIFSFSKAGYPQYVSEILEKVTCER
RYIPDAMNLVLLLVTEKLEDVALQILLSCPVSKE-------DGISDFGSFFLRHCVTMNT
PVEKLTDYCKKLKEIQMHSFPLQFTLHCALLAKKTDLAKVLMKAVKEEGF-PIRTHYFWP
LLVGHQKEKNVQGIIEVLKVMQELGVPPDQETYIGYVIPCFNSIKSARAILQENGCLSNS
D--TFSQAELRSEAINGN----LDFVLSFLESNTL-PLSLQ-SIRSSLLLGFR----RS-
------MNINL-WSKITELLYKDGRYCQEPPGPT-EAVGYFLYNLIDSMSDSEVQAKEER
LRQYFHQLKEMNVKIPENICKGIRNLLDSYHVPELIKDAYMLVDSENLDSQ----KTLRL
RSSELESRLETLKAEDQPIRDVLKQLIVALCSQENMQKALELKAKYESD-MVISG

PF01535 // ENSGT00390000016775_0_Domain_11 (836, 871)

YAALI
NLCCRHDNAEDALNL-------------KE

ENSGT00390000016775_0_Linker_11_12 (871, 888)

EFDRLDSSAVLDTSKYV

PF01535 // ENSGT00390000016775_0_Domain_12 (888, 914)

GLVRVLAKHGRLQ
DAINILKEMKKKDVPIRDSTVLSFFHILNGAALRGEIETVKQLHEAIVTLGLAKPSTNIS
FPLVTVYLEK-DDLSTALDVAIDC---CEKYKILPRMHDILCKLI-EKGETDLIQKAMDF
VSQEQGEMVMLYDLFFAFLQTGN-YKEAKKIIETPGIRARSTKLQWFCDKCIANNQVETL
EKLVE-LTQKLFECDRDQMYYNLLKLYKMNGDWQRADAVWNKIQEENIIPRGKTLRLLAE
ILRDGNQEVPFE----VPE-WYEDEK-HSLNSSLDSSSDSTTEPDFQKDILNACQLKQNK
-EAYGIFLKAKQQNVVFNAETYSDLIKLLLSKEYF-TQAVEVK-AFAETHIKGFTLNDAA
NSLLIITQVRRDYLKEALTTLKTALDQQQTPSGIAVTRLIQALAMKGDVENIEVVQKMVN
GLEDSIGLSKMVFINNTALAQIKNNNIDVAIENIEN--MLTSENPVIERQYFGLAYLFRK
VIEEQLEPAVEK----------------------------------------ISIMAERL
ANQFAIYKPVTDFFLQLVDAGKVDDARALLQRCGAIAEQTSILLVFFLRNSGKRGKA---
-STLKSLLELIPELNEKEEAYSSLMKSYASEKDVTSAKALYEHLTAKNTKLDDLFLKRYA
VLLKNAGESVPFTEPPESFEFYVQQVKELRENSS----------

------------------------------------------------------------
------------------------------------------------------------
--------ELLNQARLYATVAEKKKDLLEDSTS---RRNASSRKSPGQFDWALMTLDNSV
RKTGRITKAVS------LCS-PGNPGGNQALLLLRSCGSLLPEISLEERTDFVH

PF13812 // ENSGT00390000016775_0_Domain_5 (235, 295)

KIWDKL
QELGTVYDVSHYNALLKVYLQNKYKFSPTDFLAKMEEANIQPNRVTYQRLIAAY

ENSGT00390000016775_0_Linker_5_7 (295, 305)

CNVGDI
EGAS

PF13812 // ENSGT00390000016775_0_Domain_7 (305, 366)

KILEFMKTKDLPVTEAVFSALVTGHAKAGDMENAENILIV-MRQAGIEPGPDTYLA
LLNAYAEKGDIDHVKELERGEGRHSLIT--N--------------------------DVIVFFADAINLILLLVTEKLEDTALQXXLACPITRE-------DNQSDFGSFFLRHCVTMNTVSCL-------------------------FL---ICLAISLMKALK-EDF-PVRIHYFWPLLVGHQKEKNVQGIIDVLKGMREVGIEPDPETYLSYVFPSFDSVTSARALLQENECLPTSN--SFDVAEVKSEAMKGN----LDFVLSLCKYGLL-ALNLI---------------------GVKSMNINL-WSKLSK-----------------------------------------TLRFFFFPLFTQNIKISENIFRGIRNLLDSYHVPELIKDVYALMNK-EIDFR----KTSRITSSDLESTLEKLKNNNQPIEDVLKQLILILCSEENMQKALELKTKYESD-MVVGGYAALISLCCRHNNAEDAXXXXXXXXXXXXXSSLPAFIDRLDSSAVLDTNKYVGLVRVLGKHGKLQDAINILKEMKEKDVLIKDATVLSFFHILNGAALRGESETVKQLHEAIVTLGLAKPSTNISFPLVTVHLEK-GDLPAALETSIDC---YKKYKILPRMHDVLCKLI-EKGETDLIQKAMDFVSQEQGEMTMLYDIFFLTCLMGKAIR---KIIQ---LLFVIFKISLLCNENLFIFKIETLEKLVE-LTQKLFECDRDQLYYSLLKLYKKNGDWQSADTVWNKMQEENIIPREKTLRLLAEILKDSNQEVPFD----VPE-----------------------------------------------------QNIIFNSDTYKTLIKLL----------------FAETHIKGFTLNDAANSILIIAQVRRDYLKEALATLKTVLDLDQVPSRLSVTRLTQAFASKGDVQSIEAVQKMVSGR-DSIVLSNMIFINNIALAQIKNNNIDVAIENIEN--MLTSVDKTIEPQYFGLSYLFRKVMEEQMETAVEK-------------------------------------------------------------------------CKALLQRCGAIAEQTPILLVFFVRSAQIKGKA----PVLKSLLDLIPELRDAEEAYTSIMKSYVLDNDLPSAKMLYEH

PF13812 // ENSGT00390000016775_0_Domain_8 (305, 366)

KILEFMKTKDLPVTEAVFSALVTGHAKAGDMENAENILIV-MRQAGIEPGPDTYLALLNAYAEKGDIDHVKELERGEGRHSLIT--N--------------------------DVI
VFFADAINLILLLVTEKLEDTALQXXLACPITRE-------DNQSDFGSFFLRHCVTMNT
VSCL-------------------------FL---ICLAISLMKALK-EDF-PVRIHYFWP
LLVGHQKEKNVQGIIDVLKGMREVGIEPDPETYLSYVFPSFDSVTSARALLQENECLPTS
N--SFDVAEVKSEAMKGN----LDFVLSLCKYGLL-ALNLI-------------------
--GVKSMNINL-WSKLSK-----------------------------------------T
LRFFFFPLFTQNIKISENIFRGIRNLLDSYHVPELIKDVYALMNK-EIDFR----KTSRI
TSSDLESTLEKLKNNNQPIEDVLKQLILILCSEENMQKALELKTKYESD-MVVGGYAALI
SLCCRHNNAEDAXXXXXXXXXXXXXSSLPAFIDRLDSSAVLDTNKYV

PF01535 // ENSGT00390000016775_0_Domain_12 (888, 914)

GLVRVLGKHGKLQ
DAINILKEMKEKD

ENSGT00390000016775_0_Linker_12_13 (914, 1100)

VLIKDATVLSFFHILNGAALRGESETVKQLHEAIVTLGLAKPSTNIS
FPLVTVHLEK-GDLPAALETSIDC---YKKYKILPRMHDVLCKLI-EKGETDLIQKAMDF
VSQEQGEMTMLYDIFFLTCLMGKAIR---KIIQ---LLFVIFKISLLCNENLFIFKIETL
EKLVE-LTQKLFECDRDQL

PF01535 // ENSGT00390000016775_0_Domain_13 (1100, 1128)

YYSLLKLYKKNGDWQSADTVWNKMQEENIIPREKTLRLLAE
ILKDSNQEVPFD----VPE-----------------------------------------
------------QNIIFNSDTYKTLIKLL----------------FAETHIKGFTLNDAA
NSILIIAQVRRDYLKEALATLKTVLDLDQVPSRLSVTRLTQAFASKGDVQSIEAVQKMVS
GR-DSIVLSNMIFINNIALAQIKNNNIDVAIENIEN--MLTSVDKTIEPQYFGLSYLFRK
VMEEQMETAVEK------------------------------------------------
-------------------------CKALLQRCGAIAEQTPILLVFFVRSAQIKGKA---
-PVLKSLLDLIPELRDAEEAYTSIMKSYVLDNDLPSAKMLYEHLTSKNLKLNNLFLKRYA
LLLKNAGEPVPFTEPPESFEFYAKQLKESKETPS----------

------------------------------------------------------------
---------MAALLRPARWLLRAGAAPRLPLSLRL-------LAGGPG--RPHAARCQPT
ARAAPVPGGLLSQARLYAI-AAEKKNYLQEESA------ASQRRSASQFDWALMRLDNSV
RRTGRIPKSLLQKVFDNTCH-SGCPGGNHALLLL

PF01535 // ENSGT00390000016775_0_Domain_3 (215, 249)

RSCGSLLPELKLSERTELAHRIWDKL
QELGTVYD

ENSGT00390000016775_0_Linker_3_5 (249, 250)

V

PF01535 // ENSGT00390000016775_0_Domain_5 (250, 284)

SHYNALLKVYLQNEHKFSPTDFLAKMEGANIQPNRVTYQRLIAAYCNVGDI
EGASKILGFMKTKDLPVTE

PF01535 // ENSGT00390000016775_0_Domain_8 (320, 355)

AVFSALVTGHARAGDMENAENILTV-MKEAGIEPG

ENSGT00390000016775_0_Linker_8_7 (355, 356)

P

PF01535 // ENSGT00390000016775_0_Domain_7 (356, 390)

DTYLA
LLNVYAEKGDIDHVKQTLEKVEKSDLYLMDRDLLQIIFSFSKAGYPQYVSEILDKIAYER
RYIPDAMNLILLLVTEKLEDTALQVLLACPLSKE-------DGLNDFGSFFLRHCVTMNT
PAEKLKDYCKKLKEAKLHTSPLQFTLQCALLANKIDLAKALMKALKEEDF-PIRT

PF01535 // ENSGT00390000016775_0_Domain_10 (536, 570)

HYFWP
LLVGHQKEKNVQGIVKVLKEMHEMGVNPD

ENSGT00390000016775_0_Linker_10_11 (570, 834)

QETYVNYVFPSFDSVKSVRAVLQENGCPFES
N--IFSQAELRSEAISGN----LDYVLSFLESNTL-PFSFP-SLRGTLILGFR----RS-
------MNIDL-WSKITELLYKDGRYCQEPQGPI-EAVGYFLYNLIDSMSDSEVQAKEER
LRQYFHQLKEMNVKISENIYRGIRNLLDSYHVPELIKDVHMLVEREKTDSQ----KTIKA
SSSDLESTLEKLKAENQPVGDTLKQLILVLCSEENMQKALELKAKYESD-MVI

PF01535 // ENSGT00390000016775_0_Domain_11 (834, 881)

GGYAALI
NLCCRHDNAEEALNL-------------KQEFDRLDSSAV

ENSGT00390000016775_0_Linker_11_12 (881, 884)

LDT

PF01535 // ENSGT00390000016775_0_Domain_12 (884, 918)

NKYVALVKVLGKHGKLQ
DAINILKEMKEKDVLIK

ENSGT00390000016775_0_Linker_12_13 (918, 1098)

DTTVLSFFHILNGAALRGETETVKQLHEAIMTLGLMKPTINIC
SPLVTLYLEK-DDLPSALETSIDC---YNKYKILPRIHDVLCKLI-EKGETDLIQKAMDF
VSQEQGEMTMLYDLFFAFLQTGN-YKEAKKIIETPGIRARSARLQWFCDRCISSNQVETL
EKLVE-LTQKLFECDRD

PF01535 // ENSGT00390000016775_0_Domain_13 (1098, 1132)

QLYYNLLKLYKINSDWQRADAAWNKMQEENIIPRAKTLRLLAE
ILRNNNQEVPFD----VPELWYEDEK-DSLN----TPAPSLEEVNLQKDLLSACLRKKSK
-DAYNIFLKAQKQDVVFDSETYNNLIKLLLIKDSF-TQAMQVK-NFAETHIKGFTLNDAA
NSLLIITQVRRDYLKEALTMLKTALDQGQTPSKIAVTRLIQACALKGDLESIQAIQKMVN
GLEELIGLSNMVFINNIALAQIKNNNIDVAIENIEN--MLTSGNQTMETQYFGLAYLFRK
VIEEQLDPALEK----------------------------------------ISIMAERL
ANQFAVYKPVTDLFLQLVDSGKVDDARALLQRCGAIAEQTPIFVVFFMRSSRRPGKA---
-PILRSLIELIPELIEKE

PF01535 // ENSGT00390000016775_0_Domain_20 (1519, 1553)

EVYTSIMKSCGVDKDVSSAKALYENLTAKKIKLDDLFLKRYA
VLLKNAGEPVPFPEPPESFEFYAKQLKELRETPL----------

------------------------------------------------------------
---------MAALLRPARWLLRAGAAPRLTLSLRL------L-AGGPG--RPHAVSYLPA
ARARPVAGGLLGPARLYVI-AAEEKDI-QEES------TFSYRRITSQFDWALMRLDNSV
RRTGRIPKTLLQKVFDNTCSS-GGLGSNQALLLLRSCGSLLPEVKLEERTEFAH

PF13812 // ENSGT00390000016775_0_Domain_5 (235, 294)

RIWDKL
QELGAVYDVSHYNALLKVYLQNEYKFSQTDFLAKMEEANIQPNRVTYQRLIAS

ENSGT00390000016775_0_Linker_5_7 (294, 310)

YCNVGDI
EGASKILGF

PF17177 // ENSGT00390000016775_0_Domain_7 (310, 419)

MKTKDLPITEAVFDSLITGHARAGDMENAKNILTV-MREAGIEPGPDTYLA
LLNAYAEKGDIDHVKQTLEKVEKSELYLMDRDLFQIIFSFAKAGYPQYVSEILEKVSRER
RYIPDAMNLILLLVTEKLEDTALQILLACPVSKE-------DGLSDFGNFFLRHCVTMNT
PVEKLTDYCKKLKQVQMHSSPLQFTLSCALRDNKTDLAKDLMKAMEEEGF-PIRTHYFWP
LLVGHQKEKNVQGIIEVLKGMQELGVHPNQDTYIDYVIPCFDSVLSARAVLEENGCLPDS
D--VFSQAALRTEAIKGN----LDYILSFLKSNTS-PLSLQ-SLRNSLLLGFR----R--
-----SMNIDL-WSKITELLYKDQRYCQKPPGPT-EAVGYFLYNLIDSMSDSEVQAKEER
LRQYFHQLKEMNFKIPENIYKGIRNLLDSYHVPELIKDAHMLIDNENLSSR----KTMQL
SSSKLESTIEILKAENQPIRDVLKQLILALCLEENMQKALEVKAKYESD-MVIAG

PF01535 // ENSGT00390000016775_0_Domain_11 (836, 873)

YAALI
NLCCRHDNPEEALNL-------------KEEL

ENSGT00390000016775_0_Linker_11_12 (873, 886)

DRLDSSAVLDTNK

PF01535 // ENSGT00390000016775_0_Domain_12 (886, 914)

YVALVKVLAKHGKLQ
DAINILKEMKEKD

ENSGT00390000016775_0_Linker_12_13 (914, 1099)

VLIKDSTVLSFFHILNGAALRGEIETVKQLHEAIVTLGIAKPSTNIS
FPLVTVYLEK-DDLPAALEVAIDC---YEKYKVLPRIHDILCKLI-EKGETDLIQKAMDF
VSQEQGEMMMLYDLFFAFLQTGN-YKEAKKIIETPGIRARPARLQWFCDRCITSNQVETL
EKLVE-LTQKLFECDRDQ

PF01535 // ENSGT00390000016775_0_Domain_13 (1099, 1128)

MYYSLLKLYKVNGDWQKADAVWNKMQEENVIPREKTLRLLAE
ILKDGNQEVPFD----VPELWYEDEK-LSLDSLLNSSA---SDARFQNDILKACRLKQSK
-EAYNLFLKAKQQNVVFTAETYNDLLKLLLSKEHF-TQAMEVK-NFAETHIKGFTLNDAA
NSFLIITQVRRDYLKEALTTLKTALDQQQTPFQLAVTRLIQALAMKGDVENIEAVQKMVN
GLEDSIGLSRMVFINNIALAQIKNNNIDAAIENIEN--MLTSENQVMEPQYFGLGYLFRK
VLEEQLQPAVEK----------------------------------------ISIMAERL
ANQFAIYKPVTDFFLQLVEAGKVDDARALLQRCGAIAEQTSILLVFFIRNSRKPGKA---
-STLKSLSELIPELNEKEE

PF01535 // ENSGT00390000016775_0_Domain_20 (1520, 1548)

AYNSLMKSYASERDVTSAKALYEHLTAKNIKLNDLFLKHYS
FLLKSAGEPVPFTEPPETFEFYAQQIKESKENSS----------

------------------------------------------------------------
---------MAALLRPARWLLRAGAAPRLPLSLRL-------LTSGPG--WPHAGVCLPA
P-ARPVSGGLLHPARLYAI-AAEKKKDIREEPT-------SFKRAVSPFDWALMRLDNSV
RRTGRIPKTLLQKVFDSTCR-SGSPGGNQALLLLRSCGSLLPELTLTERTEFAHRIWDKL
QKLGTVYDVSHYNALLKVYLQNEHKFSPTDFLAKMEEANIQPNR

PF01535 // ENSGT00390000016775_0_Domain_6 (285, 314)

VTYQRLIAAYCNGGDI
EGASKILGFMKTK

ENSGT00390000016775_0_Linker_6_8 (314, 321)

DLPITET

PF01535 // ENSGT00390000016775_0_Domain_8 (321, 351)

VFSALITGHARAGDMENAQNILTV-MKETG

ENSGT00390000016775_0_Linker_8_7 (351, 357)

IEPGPD

PF01535 // ENSGT00390000016775_0_Domain_7 (357, 384)

TYLS
LLHAYAEKGDIDHVKQTLKKVEESELYLMDRDLLQIIFSFSKAGYPQHASEILEKIGYER
RYIPDAMNLILLLVTEKLEDTALQILLACPLSKE-------DGLSDFGSFFLQHCVTMNV
PMEKLIHYCKKLKEAQMHSSPLQFTLLCALQANKADLAKVLMKTMKEEGS-PVRIHYFWP
LLVKHQKKKNIQGIIEVLKGMHELGIDPDQETYVNYVFPSFDSVKSVHTALQENGCLPKD
D--TLTQAELKSEAVNGN----LDYILSVLESNTL-SFSLN-SFRTSLIQGFK----RS-
------MNINL-WSKITELLYKDGRYCQEPTGPS-EAVGYFLYNLIDSMSDSEVQAKEEH
LRQYFHQLKEMNVKIPENIYRGIRNLLDSYHVPELIKDVYVLVEREKIDSR----KTVQL
KSSDLESTLEKLKAENQPIGDVLKQLILVLCSEENMQKALELKAKYASD-MVFGG

PF01535 // ENSGT00390000016775_0_Domain_11 (836, 872)

YAALI
NLCCRHSNAEEALNL-------------KQE

ENSGT00390000016775_0_Linker_11_12 (872, 885)

LDRLDSSAVLHTR

PF01535 // ENSGT00390000016775_0_Domain_12 (885, 914)

TYVELVKVLGKHGKLQ
DAINILKEMKEKD

ENSGT00390000016775_0_Linker_12_13 (914, 1100)

VLIKDTTVTAFFHVLNGAAFRGETETVKQLHEAMVTLGLAKPSTNLS
SPLITVYLEK-GDIPGALEAIIDC---HAKYKILPRIHDVLCKLV-EKGETELIQKAMDF
VSHEQGEMMMLYDLFFAFLQTGN-YKEAKKIIETPGIRARPSRLQWFCDKCITSNQVETL
EKLVE-LTEKLFECDRDQL

PF01535 // ENSGT00390000016775_0_Domain_13 (1100, 1128)

YYSLLKLYKINGDWQRADAVWNKMQEENVIPREKTLRLLAE
ILRSSNQEVPFD----VPELWYEDET-SVQN---L-PSALPVENDLHKDLLNACHWKRNR
-DAFNIFLKAKEQNVVFNPKTYKNLIKLLLLKDCL-SQAEHVK-KFAETHIKGFTLNDAA
NSLLIITQVRRDYLKEALTTLKTALDLKQIPSRLAVTRLIQALGLKGDIESIEAIQVMIN
GLENTIGLSEMVFINNIALAQIKNNNIDVAIENIEN--LLTSGSPPVEPQYFGLAYLFKK
VLEEQLETAVEK----------------------------------------ISIMAERL
ANQFAIYKPVTDLFLQLVDAGKVDDARALLQRCGAIAEQVPIFLVFFVRNSGTEGKT---
-ATLRSLLELIPELAEKDI

PF01535 // ENSGT00390000016775_0_Domain_20 (1520, 1545)

VYTSLMKSYVVNKDVTSAKALYEHLTAKNMKLNDLFLKRYA
VLLKDAGEPLPFTEPPESFAYYAEQLKGSKEISS----------

------------------------------------------------------------
----------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXX
XXXXXXXXGLLSPARLYAI-AAEKKDF-QEES------TFSPRRNISQFDWALMRLDNSV
RRTGRIPKTLLQKVFDNTCHS-GIPGGNQALLLLRSCGSLLPELKLTERTEFAH

PF13812 // ENSGT00390000016775_0_Domain_5 (235, 294)

RIWDKL
QKLGSVYDVSHYNALLKVYLQNEHKFSPTDFLAKMEEANIQPNRVTYQRLIAA

ENSGT00390000016775_0_Linker_5_7 (294, 306)

FCNVGDI
EGASK

PF17177 // ENSGT00390000016775_0_Domain_7 (306, 419)

ILEFMKTKDLPITEAVFSALVTGHARAGDMENAENILPV-MKEAGIDPGPDTYLA
LLNAYAEKGDIDRVKQTLEKVEKSELYVLDRDLLQIIFSFSKAGYPQYVSEILEKISSER
RYIPDAMNLILLLVTEKLEDTALQILLACPVSRE-------DGQADFGSFFLQHCVNMNV
PVEKLTAYCKKLKEAQMHSSPMQFTLHCALLTNKTDLAKALMKAVKEEGF-PVRTHYFWP
LLVGYQKEKNVQGIIEVLKEMQELGVDPSQETYINYVFPSFDSVKSARAILQDNECLPKS
H--TFSQAELRSEAVNGN----LDYVLSFLESNTF-PFSFN-SLRGSLILGFR----RS-
------MNINL-WSKITELLYKDGRYCQEPPGPT-EAVGYFLYNLIDSMSDSEVQAKEER
LRQYFHQLKEMNVKIPENIYRGIRNLLDSYHVPELIKDVNMLTEREKIDSR----KTVQP
TSSELESTLETLKAENQPIGDVLKQLILLLCSEENMQKALELKAKYESD-MVVGG

PF01535 // ENSGT00390000016775_0_Domain_11 (836, 871)

YAALI
NLCCRHDNAEDALNL-------------KQ

ENSGT00390000016775_0_Linker_11_12 (871, 888)

EFDRLDSSAVLDTSKYV

PF01535 // ENSGT00390000016775_0_Domain_12 (888, 914)

GLVKVLGKHGKLQ
DAINILKEMKEKD

ENSGT00390000016775_0_Linker_12_13 (914, 1099)

VLIKDATVLSFFHILNGAALRGEIETVKQLHEAILTLGLAKPSTNLS
SPLVTVYLEK-DDLPAALEATINC---YEKYKILPRIHDVLCKLI-EKGETDLIQKAMDF
VSQEQGEMTMLYDLFFAFLQTRN-YKEAKKIIETPGIRARPTRLQWFCDRCITSNQVETL
EKLVE-LTQKLFECDRDQ

PF01535 // ENSGT00390000016775_0_Domain_13 (1099, 1128)

MYYSLLKLYKINGDWQRADAVWNKMQEENVIPREKTLRLLAE
ILRNSNQEVPFD----VPELWYEDEK-QSLSSS----SPSSVEFDFHKELSHACRWKRDK
-DAYNIFLKAKAKNTVFNTETYSNIIKLLLSKECL-PQAMEVK-DFAETHIKGFTLNDAA
NSLLIITQVRRDYLKEALTTLKTALDLHQVPFRIAVTRLIQACALKGDVQSIETIQKMVH
GLEDSIGLSRMVFINNIALAQIKNNNIDVAVENIES--MLTSGNQNVEPQYFGLAYLFRK
IIEEQLDPAVEK----------------------------------------ISIMAERL
ANQFAVYKPVTDFFLQLVDAGKVDDARALLQRCGAIAEQTSILVVFFVRNSRKPGKI---
-PTLHSLLELIPELRDQETAYASLMKSYVLDKDVTSAKALYEHLTAKNVSLNDLFLKRYA
LLLKNAGESVPFTEPPESFEFYAKQLRESNESPS----------

------------------------------------------------------------
---------MAALLRPAGRLLGAGATPRLPLSLRL-------LASGPC--RPLAAPCPPA
VRAWPVAGELLSQTRLYSI-VAEKKSVLQEEPT------ISPSRNAKQFDWALMRLDNSV
RRTGRITKGLLQKVFDSTCR-SDNPSGNQALLLLRSCGSLLPELSFTERTEFAHT

PF13812 // ENSGT00390000016775_0_Domain_5 (236, 294)

IWDKL
QKLGAVYDVSHYNALLKVYLQNEYKFSPTDFLTKMEEANIQPNRVTYQRLIAA

ENSGT00390000016775_0_Linker_5_7 (294, 310)

YCSVGDI
EGASKILGF

PF17177 // ENSGT00390000016775_0_Domain_7 (310, 418)

MKTKDLPITEAVFSALVTGHARAGEMENAENILTV-MKDAGIEPGPDTYVA
LLNAYAEKGDINHVKQTLEKVEKSDLYLMDRDLLQVIFSFSKAGYPQYISEILEKITYER
RYIPDAMNLILLLVTEKLEDTALEILLACPISRE-------DNSVDFGSFFLRHCVTMNT
PKEKLINYCRKLKEARMHTSPLQFTLHCALTTHKTDLAVAVMKALKEDGF-PLRTHYFWP
LLVAHKKEKNVQGIIDVLKVMYEFGVHPDQETYVNYVFPSFDSIKSVRALLEENKCLPKS
N--TFSQAEIRSEAINGN----LDYILSCLESSTL-PFSFN-SLRGSLILGFR----RS-
------MNVDL-WSKITELLYKNGRYCQEPPGPT-EAVGYFLYNLIDSMSDSEVQAKEEH
LRQYFHQLKEMNIKISENIYRGIRNLLDSYHVPELIKDVKLLVDREKIDSQ----KTSQL
TSSDLESTLEQLKAKNQPIGDTLKQLILMLCSEENMQKALELKEKYESD-MVIGGYAALI
NLCCRHANAEDALSL-------------KQQFDRLDSSAVLDTNKYIG

PF01535 // ENSGT00390000016775_0_Domain_12 (889, 914)

LVKVLGKHGKLQ
DAINILKEMKEKD

ENSGT00390000016775_0_Linker_12_13 (914, 1099)

VLIKDSTVLSFFHILNGAALRGEIETVKQLHEAIVTLGLAKPSTSIS
FPLVTVHLEK-NDLPAALEATIDC---YAKYKILPRIHDVLCKLI-EKGETDLIQKAMDF
VSQEQGEMTMLYDLFFAFLQTGN-YKEAKKIIETPGIRARPSALQWFCERCITSNQVETL
EKLVE-LTQKLFECDRDQ

PF01535 // ENSGT00390000016775_0_Domain_13 (1099, 1128)

MYYSLLKLYKINGDWQRADAVWNKMQEENVIPREKTLRLLAE
ILRNSNQEVPFD----VPELWYEDEK-QKLS---S-SSPSPVGANIEKDVLKACHSRRNK
-DAYNIFLRAQKQNTVFSSETYDTLIKFLL-KDNF-VQAMEVK-DFAETHIKGFTLNDAA
NSLLIITQVRRDYLKGALATLQTSVNLQQTPSRLAVTRLIQALALKGDIQSIEAIQKMVD
GLD-SIGLSNMVFINNIALAQIKNNKIDVAIENIEN--MLTSENQLIQPQYFGLSYLFRK
VIEEQLDPAMEK----------------------------------------LSIMAERL
ANQFAIYKPVTDLFLQLVELGKVDDARALLQRCGAIAEQSSILSVFCVRTSQKQGKA---
-PVLKTLLELIPELVEKEEAYCSAMKSYVLDKDVASAKALYEQLTARNTKLNDLFLKRYA
LLLKNAGESVPFTEPPESFEFYAKQLKESKETPS----------

------------------------------------------------------------
---------MAALLRPARWLLAAGVPPRLPLSLRF-------LAAGPG--RPRVVSCLPA
ARARPFAGELLNQARLYAI-AAERKNDLEENSS-HRRNASFPRRDTDQFSWALMRLDTSV
RRTGRITKGLLQKVFESTCH-SGNPSGNQALLLLRSCGSLLPEISFKERTDFVHK

PF13812 // ENSGT00390000016775_0_Domain_5 (236, 295)

IWDRL
QELGTVYDVSHYNALLKVYLQNKYKFSPTDFLAKMEEANIQPNRVTYQRLIAAY

ENSGT00390000016775_0_Linker_5_7 (295, 306)

CNVGDI
EGASK

PF17177 // ENSGT00390000016775_0_Domain_7 (306, 418)

ILEFMKNKDLPVTEGVFSALVTGHATAGDMENAENILTV-MRETGIEPGPDTYLA
LLNAYAEKGDIDHVKQTLEKVQKSDLYLMDRDLLQLIFSFSKAGYPQYVSEVLEKITYER
RYIPDAMNLILLLVTEKLEDTALQVLLACPVSRE-------GSLTNFGNFFLRHCVTMNT
PAEKLIDYCKKLKDAQMHTTPLQFTLHCALQGSKTDLAKTLIKALKEEGF-PVRTHYFWP
LLVGHQKERNVQGIIDILKAMREVGVEPDQETYVNYVLPSFDNVESVRVLLQENECLPES
T--SFGIAELRSEAVKGN----LDFVLSFLKSNTL-PLSFN-SLRKSLILGFR----RS-
------MNIHL-WSKITELLYKDGRYCQEPPGPR-EAVGYFLYNLIGSMSDSEVQANEEH
LRQYFHQLKEMNIKIYENIYRGIRNLLDSYHVPELIKDVNILVEREKRDSQ----KT---
-SSDLEATLEKLKDNNQPIGDVLKQLILTLCSEENMQKALEVKTKYESD-MVVS

PF01535 // ENSGT00390000016775_0_Domain_11 (835, 873)

SYAALI
NLCCRHDNAEDALNL-------------KQEF

ENSGT00390000016775_0_Linker_11_12 (873, 888)

ERLDSSAVLHTNKYV

PF01535 // ENSGT00390000016775_0_Domain_12 (888, 914)

GLVKVLGKHGKLQ
DAINILKEMKEKN

ENSGT00390000016775_0_Linker_12_13 (914, 1100)

VPIQDATLLSFFHILNGAALRGEIETVKQLHEAIVTLGLAKPSTNIS
FPLVTVHLEK-GDLLAALEAMIVC---YKKYKILPRMHDVLCKLV-EKGETDLIQKAMDF
VSQEQGEMTMLYDIFFAFLQTGN-YKEAKKIMETPGIRARPTKLQWFCDRCITNNKREAL
EKLVE-LTQNLFECDRDQL

PF01535 // ENSGT00390000016775_0_Domain_13 (1100, 1128)

YYSLLKLYKKNGDWQRADAIWNKMQEENIIPREKTLRLLAD
ILKDNNQEVPFD----VPELWYDDDE-HSPN-----SSPRPVDPLTEKAVLNACQQRKNR
-DAYNIFLRAQRQNIIFSSDTYRTLTQLLLLTDNF-TQAIEVK-MAAETHIKGFTLNDAA
NSFLIIAQVRRDYLKEALTTLKTALDLDQTPSKLSVTRLIQAFASKGDVQSVEAIQKMVS
GHD-SIGLSGMIFINNIALAQIKNNNIDVAIENIEN--MLTSGNQTIESRYFGLSYLFRK
AIEEQIEPAVEK----------------------------------------LSIMAERL
ANQFAVYKPVTDLFLQLVQLGKVDDARALLQRCGAIAEQTPILLVFCFRIAQQKGKA---
-PVLNSLLELIPELREKEEAYTSAMKTYVLDNDVPSAKMLYKYLTAKNMKMNDLFLKRYA
LLLKNAGEPVPFIEPPESFEFYSKQLKESKENPS----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------TPGGSQVLLLLRSCGSLLPELQLSERTALAHKIWDKL
KELGAVYDVSHYNALLKVYLQNEHRFSPTDFLAQMEKANVQPNR

PF01535 // ENSGT00390000016775_0_Domain_6 (285, 319)

VTYQRLIAAYCHAGDI
QGASTVLSFMKTKDLPV-

ENSGT00390000016775_0_Linker_6_8 (319, 320)

E

PF01535 // ENSGT00390000016775_0_Domain_8 (320, 355)

AVFSALVTGHARAGDMENAENIFSV-MREAGIEPG

ENSGT00390000016775_0_Linker_8_7 (355, 356)

P

PF01535 // ENSGT00390000016775_0_Domain_7 (356, 390)

DTYLA
LLSAYAEKGDIDRVKQTLEKVEKSDLYLMDRDLLQLIFSFSKAGHPQHVSEILSRITYER
RYIPDVMNLILLLVTEKMEDTALEVLLACPVSRE-------DSGSDFGNFFLRHCVAVDT
PAEKLRDYCRKLKEARMHTSALQFTLYCALAANKLGLAKTLMKALAEDGF-PLRT

PF01535 // ENSGT00390000016775_0_Domain_10 (536, 570)

HYFWP
LLVAHQKEKNVQGVVEVLQGMQEVGVSPD

ENSGT00390000016775_0_Linker_10_11 (570, 834)

QETYVSYVFPAFESVARARAVLQXXXXXXXX
X--XXXXXXXXXXXXXXX----XXXXXXXXKSNTQ-PLSLP--PKGSLILGFR----RS-
------VNVDL-WSKITELLYHDDRYRQDPLGPT-EAVGYFLYSLIDSMSDSEVQAEEAR
LRQYFHQLKEMNVKIPENIYRGIRNVLDSRHAPELIKDVIVLIERETIDSQK---TEQRL
TSSDLEATLEKLKSENQPVRAALRQLILALCAEENMQKALELKAKYESD-MSV

PF01535 // ENSGT00390000016775_0_Domain_11 (834, 881)

GGYAALI
SLCCRHDDAEAALSL-------------KHELERLDSSAV

ENSGT00390000016775_0_Linker_11_12 (881, 884)

LDT

PF01535 // ENSGT00390000016775_0_Domain_12 (884, 918)

SKYMALVRVLGKHGQLP
DAINILREMKEKDVPIR

ENSGT00390000016775_0_Linker_12_13 (918, 1098)

EASVLSFFHILNSAALRGEVDTVKQLFEAIVTLGLAKPTTSLT
GPLVTLYLRK-EDLPGALSVAMDC---YQKYKTLPRMHDLLCRLI-EKGETELIHKAMDF
VSQEQGEMTMLYDLFFAFLETGN-DKEAKKIIETPGIRARPMRLQWFCDRCITNNQVETL
EKLVE-LTQKLFECDRD

PF01535 // ENSGT00390000016775_0_Domain_13 (1098, 1132)

EMYFNLLKLHKVNGDWQKADAVWNKMQEENIIPRAKTLRLLAE
ILRNSNQEVPFD----VP------------------------------------------
-EAFNVFLKAEKQNVVLSSDAYDRLLNLLLSRDGSLEQALQVK-KAAETHIKGFTLNEAA
NSLLIITQVRRDYLKEAMATLRTAFSLQQLPSRLAVTRLIQACALKGDLGSIQEIQKLVT
GLEDSIGLSHMVFINNVALAQIKNNDVQAAVESIET--MLTSGDPAVEPQFFGLSYLFRK
LIEERLEPALER----------------------------------------MSVMAERL
ANQFAVYKPVTDLFLQLVESGKVDEARALLQXXXXXXXXXXXXXXXXXXXXXXXXXA---
-PVLKSLSELIPELTDREEVYTSFMKSY--------------------------------
--------------------------------------------

------------------------------------------------------------
---------MAALLRPARWLLRAGVAPRLPLSLRL-------FAGGPG--RPHGVPGLPA
ARAGPVAGGLLNPARLYAI-AAERKNDIQEEL-------TSLRRTASQFDWALMRLDNSV
RRTGRIPKRLLQKVFDNTCR-SGTPGGNQALLLLRSCGSLLPELTLTERTEFAH

PF13812 // ENSGT00390000016775_0_Domain_5 (235, 295)

RIWDKL
QELGTVYDVSHYNALLKVYLQNEYKFSPTDFLAKMEETNIQPNRVTYQRLIAAY

ENSGT00390000016775_0_Linker_5_7 (295, 308)

CNVGDI
EGASKIL

PF17177 // ENSGT00390000016775_0_Domain_7 (308, 417)

GFMKTKDLPVTEAVFSALITGHARAGDMENAENILTV-MKDAGIEPGPDTYLA
LLNAYAEKGDIDHVKQTLEKVGKSDLYLMDRDLLQLIFSFSKAGYPQYASEILEKITYER
RYIPDAMNLILLLVTEKLEDTAFQILLACPISRE-------DGLSDFGSFFLQHCVTMNT
PVEKLTDYCRKLKEAQMHSSPLQFTLHCALLHNKADLAKALMKAMKEEGI-PVRTHYFWP
LLVEHQKKKNVQGIIEVLKGMHELGVEADQETYINYVFPSFESVKSVRTVLQENGCLPES
S--MFAQAELRSEAVNGN----LEYILSFLKSNTL-PFSFN-SFRGSLILGFR----RS-
------MNIDL-WSKITELLYKDGHYCQEPPGPT-EAVGYFLYNLIDSMSDSEVQAKEER
LRQYFHQLKEMNVKIPENIYRGIRNLLDSYHVPELIKDIYLLIDREKIDSR----KTVQF
TSSNLESTLERLKAENQPVGDVLKQLILMLCSEENMQKALELKAKYESD-MVVGG

PF01535 // ENSGT00390000016775_0_Domain_11 (836, 871)

YAALI
NLCCRHDNAEEALNL-------------KQ

ENSGT00390000016775_0_Linker_11_12 (871, 888)

EFDRLDSSAVLNTGKYV

PF01535 // ENSGT00390000016775_0_Domain_12 (888, 914)

GLVKVLGKHGKLQ
DAINILKEMKEKD

ENSGT00390000016775_0_Linker_12_13 (914, 1099)

VLIKDATVLSFFHILNGAALRGEIETVKQLHEAIVTLGLAKPSTNLS
SPLVTVHLEK-DDIPAALEATIDC---FRKYKILPRIHDVLCKLI-EKGETDLIQKAMDF
VSQEQGEMMMLYDLFFAFLQTGN-YKEAKKIIETPGIRARPARLKWFCDRCITNNQVETL
EKLVE-LTQKLFECDRDH

PF01535 // ENSGT00390000016775_0_Domain_13 (1099, 1128)

MYYNLLKIYKINGDWKRADAVWNKMQEENVIPREKTLRLLAE
ILRNSNQEVPFD----VPELWYEDEN-DSQN---SSLSTSPVENDLQKDVLKACQWKNNT
-DAYDIFLKAQEQNVVFKSKTYDTLIRLLLSKECL-AEAMHVK-DFAETHIKGFTLNDAA
NSLLIITQVRRDYLKEALTTLKTALDLKQIPSRVAVTRLIQAFALKGATEGIEEIQKMVN
GLEDSIGLSNMVFINNIALAQIKNNNIDVAIENIEN--MLTSENQTVDPQYFGLAYLFRK
VIEEQLEPAVEK----------------------------------------ISIMAERL
ANQFAVYKPVTDLFLQYVEAGKVDDARALLQRCGAIAEQIPIFMVFFVRNSRKPGKA---
-STLQSLLGLIPELVEKEE

PF01535 // ENSGT00390000016775_0_Domain_20 (1520, 1549)

AYTSLMKSYALDKDVTSAKALYEHLTEKNVKLNDLCLKRYA
LLLKNAGEPVPFPEPPETFEFYVKQLKESKENSL----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------MEEANIQPNRVTYQRLIAAYCNIGDI
EGAS

PF17177 // ENSGT00390000016775_0_Domain_7 (305, 418)

KILEFMKTKDLPVTEAVFSALVTGHAKAGDMENAENILIV-MRQAGIEPGPDTYLA
LLNAYAEKGDIDHVKEILEKVQKSDLYLMDRDLLQLVFSFSKAGYPQYVSEILEKFTYER
RYIPDAINLILLLVTEKLEDTALQVLLACPITRE-------DNQSDFGSFFLRHCVTMNT
PAEKLTDYCKKLKEAHMHTSPLRFTLHCALQANKTGLAISLMKALK-EDF-PVRIHYFWP
LLVGHQKEKNVQGIIDVLKGMREVGIEPDPETYLSYVFPSFDSVTSARALLQENECLPTS
N--SFDVAEVKSEAMKGN----LDFVLSLLESNTL-PLSFN-SLRGSLVLGFK----RS-
------MNINL-WSKITELLYKDGRYCQELSGPT-EAVGYFLYNLIDSMSDSEVQAKEER
LRQYFHQLKEMNIKISENIFRGIRNLLDSYHVPELIKDVYALMNK-EIDFR----KTSRI
TSSDLESTLEKLKNNNQPIEDVLKQLILILCSEENMQKALALKTKYESD-MVVGG

PF01535 // ENSGT00390000016775_0_Domain_11 (836, 871)

YAALI
SLCCRHNNAEDALNL-------------KQ

ENSGT00390000016775_0_Linker_11_12 (871, 888)

EFDRLDSSAVLDTNKYV

PF01535 // ENSGT00390000016775_0_Domain_12 (888, 914)

GLVRVLGKHGKLQ
DAINILKEMKEKD

ENSGT00390000016775_0_Linker_12_13 (914, 1100)

VLIKDATVLSFFHILNGAALRGESETVKQLHEAIVTLGLAKPSTNIS
FPLVTVHLEK-GDLPAALEASIDC---YKKYKILPRMHDVLCKLI-EKGETDLIQKAMDF
VSQEQGEMTMLYDIFFAFLQTGN-YKEAKKIIETPGIRARPAKLQWFCERCITNNQIETL
EKLVE-LTQKLFECDRDQL

PF01535 // ENSGT00390000016775_0_Domain_13 (1100, 1128)

YYSLLKLYKKNGDWQSADTVWNKMQEENIIPREKTLRLLAE
ILKDSNQEVPFD----VPELWYEDST-DTPV-----SSLAPVNPLIEKELLKACRQRKNR
-DAYNIFLKAQEQNIIFNSDTYRTLIKLLLLKDSF-TEAMQVK-NAAETHIKGFTLNDAA
NSILIIAQVRRDYLKEALATLKTVLDLDQVPSRLSVTRLTQAFASKGDVQSIEAVQKMVS
GRD-SIVLSNMIFINNIALAQIKNNNIDVAIENIEN--MLTSVDKTIEPQYFGLSYLFRK
VMEEQMETAVEK----------------------------------------LSIMAERL
ANQFAVYKPVTDLFLQLVNSGKVDDARALLQRCGAIAEQTPILLVFFVRSAQIKGKA---
-PVLKSLLDLIPELRDTEEAYTSTMKSYVLDNDLPSAKMLYEHLTAKNLKLNNLFLKRYA
LLLKNAGEPVPFTEPPESFEFYAKQLKESKETPS----------

------------------------------------------------------------
---------MAALLRPARWLLCAGVSPRLPLSLRF-------LAGGTS--RPLGASCLPA
ARARPFAGELLNQARLYTI-IAKRKNDLLEENASPRKNASSPGRDTNQFSWALMALDNSV
RRTGRITKQLLQKVFDSTCH-SGNPSGNQALLLLRSCGSLLPEISLQERTDFVHK

PF13812 // ENSGT00390000016775_0_Domain_5 (236, 295)

IWNKL
QELGTVYDVSHYNALLKVYLQNKHKFSPTDFLAKMEEENIQPNRVTYQRLIAAY

ENSGT00390000016775_0_Linker_5_7 (295, 306)

CNVGDI
EGASK

PF17177 // ENSGT00390000016775_0_Domain_7 (306, 417)

ILEFMKTKDLPVTEAVFSALVTGHAKAGDMENAENILTV-MREAGIEPGPDTYLA
LLNAYAEKGDIDHVNQTLEEVQKSDMYLMDRDLLQLVFSFSKAGYPQYVSEVLEKLSYER
RYIPDAMNLILLLVTEKLEDTALQVLLACPVSRE-------GNLTDFGSFFLRHCVTMNT
PSEKLIDYCKKLKEAQMHTTALQFTLCCALQEKKTDLAKALIKTLKEEGF-PVRTHYFWP
LLAGHQKERNVQGIIDVLKEMHAVRVEPDQETYINYVFPSFDSVKSLCALLQENECIPES
N--SLAVAEVRCKAAAGD----LDFVLSFLKSNTL-PLSFN-SLRGSLILGFK----RS-
------MNINL-WSEITELLYKDGRYCQEPPGPT-EAVGYFLYNLIDSMSDSKVQAKEEH
LRQYFHQLKEMNIKISANIYRGIRNLLNSYHVPELIKDVKVLVESENTDSQ----KTSQL
TSSDLEAMLEKLRDSNQPIGDVLKQLIFMLCAEENMQKALELKAKYESD-MVAAG

PF01535 // ENSGT00390000016775_0_Domain_11 (836, 871)

YVALI
KLCCRHNNAEDALNL-------------KQ

ENSGT00390000016775_0_Linker_11_12 (871, 885)

EFDRLDSSVVLHTG

PF01535 // ENSGT00390000016775_0_Domain_12 (885, 914)

SYVDLIKVLGKHGRLQ
DAINILKEMKEKD

ENSGT00390000016775_0_Linker_12_13 (914, 1100)

VPIQDRTVMSFFHILNAAALRGEIETVQQLHEAIVTVGLAKPSSILS
SPLVIVHLEK-GDVLAALEAMIVC---CEKYKVLPKVHDVLCKLI-EKGETDLIQKAMDF
VSQEQGEMMMLYDIFFAFLQTGN-YKEAKKIMETPGIRARPIKLQWFCHKCIINNQRKTL
EKLVE-LTQNLFECDRDQL

PF01535 // ENSGT00390000016775_0_Domain_13 (1100, 1128)

YYSLLKLHKRNGDWQRADAVWNKMQEENIIPREKTLRLLAD
ILKDSNQEVPFD----VPELWYDTDE-HSSN-----SSPPLVDPLTEKEVLNACQLLKNR
-DAYDIFLKAQKQNIAFNSDTYRTLIQFLLWRDNF-TQAMKVK-DVAETHIKGFTLNDAA
NSLLIRTQVRRDYLKEALTTLKTALDLDQIPSEQAVTCLIQALATKGDVQSIEAIQKMVS
GID-SIGLSKMVFINNIALAQIKNNNIDVAIENIEN--MLTSGNQTIEHRYFGLSYLFRK
VIEGQIEPAVEK----------------------------------------LSIMAERL
ANQFAIYKPVTDLFLQLVDLGKVDDARALLQRCGAVAEQTPILSVFCLRNASKQGKA---
-PVLKSLLELIPELHEKEQVYTSAMKSYVFDNDVPSAKILYEYLTAKNMKLNDLFLKRYA
YLLKKAGESVPFTEPPESFQFYAKQLKESNENPS----------

------------------------------------------------------------
---------MAALLRPARWLLGAAAAPRLPLSLRL-------PAGGPG--RLSSVARVAA
VGGRPAAGELLSQARLYAI-VAE-KRDLQEEPA-------PVRKSGSQFDWALMRLDNSV
RRTGRITKGLLQKVFESTCR-SGNPGSNQALLLLRSCGSLLPELSLAERTEFAHKIWEKL
QQLGVVYDVSHYNALLKVYLQNEYKFSPTDF

PF13812 // ENSGT00390000016775_0_Domain_6 (272, 313)

LAKMEGANIQPNRVTYQRLIAAYCNVGDI
EGASKILGFMKA

ENSGT00390000016775_0_Linker_6_7 (313, 322)

KDLPITEAV

PF13812 // ENSGT00390000016775_0_Domain_7 (322, 365)

FSALITGHARAGDMENAENILTV-MKQAGIEPGPDTYLA
LLNAHAERGDIGHVKQILEKVEKSDHYFMDRDFLQVIVSFSKAGYPQYISEILEKITYERRSIPDAMNLILLLVTEKLEDTAFQVLLALPLSKD-------ETSNNIGSFFLRHCVTMDTPPEKLIDYCRRLRDAKLHSSSLQFTLHCALQANKTDLAKAVMEALREEGF-PIRPHYFWPLLAGHQKTKNVQGIIDILKIMNEMAVDPDQETYINYVFPCFDNAQSVRAALQENKCLFKST--TLAQAEVRNEAINGN----LQNILSFLESNTL-PFSFS-SLRNSLILGFR----RS-------MNIDL-WSKITELLYTDGRYCSKPLEPT-EAVGYFLYNLIDSMSDSEVQAKEEHLRQYFHQLQEMNVKVPENIYKGICNLLNNYHVPELIKDIKVLVDREKVDSQ----KTSQVTSSDLESTLEKLKAEGQPVGAVLKQLLLLLCSEENMQKALEVKAKYESD-MVIGGYAALINLCCRHDNAEDAWNL-------------KQEVDRLDPSALLDTAKYTALVKVLGKHGRLQDAINILKEMKEKDVVIKDATVLSFFHILNGAALRGETETVKQLHEAIVTLGLAKPSSNISFPLVTVHLEK-DDLPAALEASIAC---HEKYKILPRIHDVLCKLI-EKGETDLIQKAMDFVSQEQGEMTMLYDLFFAFLQTGN-YKEAKKIIETPGIRARPARLQWFCDRCIASNQAETLEKLVE-LTEKLFECDRDQMYYSLLKLYKISNDWQRADAVWNKIQEENIIPRERTLRLLAEILKTSNQQVPFD----VPELWFGDDR-PSLS---S-SSPPAGDTVTEKTLLSDCRLKKNK-DAYNIFLKAEKQNVVFSSETYSTLIGLLLSKDDF-TQAMHVK-DFAETHIKGFTLNDAANSLLIIRQVRRDYLKAALATLRATLDLEQVPSELAVTRLIQALALKGDVESIEAIQKMVNGLD-TIGLSKMVFINNIALAQMKNNKIDAAIENIEH--MLASENQVIEPQYFGLSYLFRKVIEEQMGPALEK----------------------------------------LSIMSERLANQFALYKPVTDLFLQLVDSGKVDEARALLERCSAIAEQSSILSVFCLRTAQKPKKA----PVLKTLLELIPELRENHKVYSCSMKSYVLDKDVASAKALYEHLTAKNLKLDDLFLKRYAS

PF13812 // ENSGT00390000016775_0_Domain_8 (322, 365)

FSALITGHARAGDMENAENILTV-MKQAGIEPGPDTYLALLNAHAERGDIGHVKQILEKVEKSDHYFMDRDFLQVIVSFSKAGYPQYISEILEKITYER
RSIPDAMNLILLLVTEKLEDTAFQVLLALPLSKD-------ETSNNIGSFFLRHCVTMDT
PPEKLIDYCRRLRDAKLHSSSLQFTLHCALQANKTDLAKAVMEALREEGF-PIRPHYFWP
LLAGHQKTKNVQGIIDILKIMNEMAVDPDQETYINYVFPCFDNAQSVRAALQENKCLFKS
T--TLAQAEVRNEAINGN----LQNILSFLESNTL-PFSFS-SLRNSLILGFR----RS-
------MNIDL-WSKITELLYTDGRYCSKPLEPT-EAVGYFLYNLIDSMSDSEVQAKEEH
LRQYFHQLQEMNVKVPENIYKGICNLLNNYHVPELIKDIKVLVDREKVDSQ----KTSQV
TSSDLESTLEKLKAEGQPVGAVLKQLLLLLCSEENMQKALEVKAKYESD-MVIGGYAALI
NLCCRHDNAEDAWNL-------------KQEVDRLDPSALLDTAK

PF01535 // ENSGT00390000016775_0_Domain_12 (886, 914)

YTALVKVLGKHGRLQ
DAINILKEMKEKDVVIKDATVLSFFHILNGAALRGETETVKQLHEAIVTLGLAKPSSNIS
FPLVTVHLEK-DDLPAALEASIAC---HEKYKILPRIHDVLCKLI-EKGETDLIQKAMDF
VSQEQGEMTMLYDLFFAFLQTGN-YKEAKKIIETPGIRARPARLQWFCDRCIASNQAETL
EKLVE-LTEKLFECDRDQMYYSLLKLYKISNDWQRADAVWNKIQEENIIPRERTLRLLAE
ILKTSNQQVPFD----VPELWFGDDR-PSLS---S-SSPPAGDTVTEKTLLSDCRLKKNK
-DAYNIFLKAEKQNVVFSSETYSTLIGLLLSKDDF-TQAMHVK-DFAETHIKGFTLNDAA
NSLLIIRQVRRDYLKAALATLRATLDLEQVPSELAVTRLIQALALKGDVESIEAIQKMVN
GLD-TIGLSKMVFINNIALAQMKNNKIDAAIENIEH--MLASENQVIEPQYFGLSYLFRK
VIEEQMGPALEK----------------------------------------LSIMSERL
ANQFALYKPVTDLFLQLVDSGKVDEARALLERCSAIAEQSSILSVFCLRTAQKPKKA---
-PVLKTLLELIPELRENHKVYSCSMKSYVLDKDVASAKALYEHLTAKNLKLDDLFLKRYA
SLLKDVGEPVPFPEPPESFAFYIKQLKEAQENPS----------

------------------------------------------------------------
---------MAALLRPARWLLRASVSPRLPLSRRL-------LAGGPG--RPLVASRLPA
ARARPPAGELLNQARLYAI-VAEEKNDFLDENT-SRRNTS-SRRHPGQFDWALMTFDNSV
RKTGRITKRLLQKVFDRTCH-SGNPGSNQALLLLRSCGSLLPEISLKERTDFVHE

PF13812 // ENSGT00390000016775_0_Domain_5 (236, 295)

IWNKL
QKLGTVYDVSHYNALLKVYLQNRYEFSPTDFLAKMEEANVQPNRVTYQRLIAAY

ENSGT00390000016775_0_Linker_5_7 (295, 305)

CNVGDI
EGAS

PF17177 // ENSGT00390000016775_0_Domain_7 (305, 418)

KILEFMKTKDLPVTEAVFSALITGHAKAGDMENAENILTV-MREAGIEPGPDTYLA
LLNAYAEKGDIDHVKQTLEKAQNSDLYLTDRDLLQLIFSFSKAGYPQYVSEILEKLTYER
RYIPDAINLILLLVTEKLEDTALQVLLACPVSKE-------ENQNDFGNFFLRHCVTMNT
PVEKLTDYCKKLKEAQMHSSPLQLTLYYALQANKADLATALMKALKEEGF-PVRIHYFWP
LLVGQQKERNVQGIVDVFKRMQEVGVEPDPETYISYVFPSFDSVTAVRALLQENNCVPKN
N--SLGVAEMRSEAMKGN----LNFVLSFLESNTL-PLSLN-SLRGSLITGFR----RS-
------MNINL-WSKITELLYKDGRYCQEPPGPT-EAVGYFLYNLIDSMSDSEVQAKEEH
LRQYFHQLEEMNIKISENIYRGIRNLLDSYHVPELIKDVNVLVDREKTDSR----KTSQF
TSSELESTLEKLKGDNQPIGDVLKQLILVLCSEENMQKALELKEKYESD-MVVGG

PF01535 // ENSGT00390000016775_0_Domain_11 (836, 871)

YAALI
NLCCRHDNAEDALNL-------------KQ

ENSGT00390000016775_0_Linker_11_12 (871, 888)

EFDRLNSSAVLDTNKYV

PF01535 // ENSGT00390000016775_0_Domain_12 (888, 914)

GLVRVLGKHGKVQ
DAINILKEMKEKD

ENSGT00390000016775_0_Linker_12_13 (914, 1100)

VLIKDATVLSFFHILNGAALRGEIETVKQLHEAIVMLGLAKPSTNIS
IPLVTVHLEK-GDLSAALETTIDC---YKKYKILPRLHDILCKLI-EKGETALIQKAMDF
VSQEQGEMTMLYDIFFAFLQTGN-YKEAKKIIETPGIRARPTRLQWFCDKCITNNQIETL
EKLVE-LTQKLFECDRDYL

PF01535 // ENSGT00390000016775_0_Domain_13 (1100, 1128)

YYSLLKLYRKNGDWQRADAVWNKMQEENIIPREKTLRLLAE
ILKDGNQEVPFD----VPELWYEGST-CSPI------SPSHVDPLTEKELLKACEQQKNQ
-DAFSIFLKAQNKNIMFSSDTYTTLIHLLLLKDSF-SEAMKVK-DTAETHIKGFTLNDAA
NSILIITQVRRDYLKEALATLKTALDLDQIPSKFSVTRLIQTFASKGDVQSIEAIQKMVS
GRD-EIGLSRMVFINNIALAQMKNNNIDVAVENIEN--MLTSGNPVVAPQYFGLSYLFRK
AIEGHMETAVEK----------------------------------------LSIMAERL
ANQFSVYKPVTDLFLQLVDSGKVDDARALLQRCGAIAEQTPILLVFCIRNAQKQGKA---
-SVLKSLFELIPELHDREEAYTSIMKSYVVDNDVSSAKRLYEHVTTKNMKLNNLFLKRYA
VLLKKAGESVPFTEPPESFEFYANQLKESKETPF----------

------------------------------------------------------------
---------MAALLRPARWLLRAGAAQRLTLSLRL------L-AGGPG--RPHVVSYLPA
ARAKPVAGGLLGPARLYVI-AAEEKDI-QEES------TFSYRRITSQFDWALMRLDNSV
RRTGRIPKTLLQKVFDNTCSS-GDPGSNHALLLLRSCGSLLPEVKLEERTEFAH

PF13812 // ENSGT00390000016775_0_Domain_5 (235, 296)

RIWDKL
QELGAVYDVSHYNALLKVYLQNEYKFSQTDFLAKMEEANIQPNRVTYQRLIASYC

ENSGT00390000016775_0_Linker_5_7 (296, 308)

NMGDI
EGASKIL

PF17177 // ENSGT00390000016775_0_Domain_7 (308, 417)

GFMKTKDLPITEAVFNSLITGHARVGDMENAENILTV-MKEAGIEPGPDTYLA
LLNAYAEKGDIDHVKQTLEKVEKSELCLMDRDLLQIIFSFAKAGYPQYVSEILEKVTCER
RYIPDAMNLILLLVTEKLEDTALQILLACPISKE-------DSLSDFGNFFLRHCVTMNT
PVEKLTDYCKKLKEVQMHSCPLQFTLSCALLANKTDLAKDLMKAMKEEGF-PIRTHYFWP
LLVGHQKEKNVQGIIEVLKGMQELGVHPNQETYINYVIPCFDSVPSARAILEENGCLSNS
D--TFSQAALRTEAVKGN----LDYILSFLESNTS-PLSLQ-SVRGNCICSCL----LLL
----LQCTNFL-SYQITELLYKDRRYCQKPPGPT-EAVGYFLYNLIDSMSDSEVQAKEER
LRQYFHQLKEMNLKIPENTYKGIRNLLDSYHVPELIKDAHMLVDNENLGSR----KTVQL
SSSKLESTIETLKAENQPIRDVLKQLILALCSEENMQKALEVKAKYESD-MVIAG

PF01535 // ENSGT00390000016775_0_Domain_11 (836, 873)

YAALI
NLCCRHDNAEDALNL-------------KEEL

ENSGT00390000016775_0_Linker_11_12 (873, 886)

DRLDSSAVIDTNK

PF01535 // ENSGT00390000016775_0_Domain_12 (886, 914)

YVALVKVLAKHGKLQ
DAINILKEMKEKD

ENSGT00390000016775_0_Linker_12_13 (914, 1099)

VLIKDATVMSFFHILNGAALRGEIETVKRLHEAIVTLGLAKPSTNIS
FPLVTVYLEK-DDLSAALEVAIDC---CEKYKILPRIHDILCKLI-EKGETDLIQKAMDF
VSQEQGEMMMLYDLFFAFLQTGN-YKEAKKIIETPGIRARPTRLQWFCDRCIASNQVETL
EKLVE-LTQKLFECDRDQ

PF01535 // ENSGT00390000016775_0_Domain_13 (1099, 1128)

MYYSLLKLYKVNGDWQKADAVWNKMQEENVIPREKTLRLLAE
ILRDGNQEVPFD----VPELWYEDEK-LSLDSSLNSSSTSTSDLGFQNDILKACQLKQSK
-GAYDIFLKAKQQNVVFNAETYNDLLKLLLSKEYF-TQAMEVK-KFAETHIKGFTLNDAA
NSLLIITQVRRDYLKEALTTLKTALDQQQTPSQLAVTRLIQALAMKGDVENIEAVQKMVN
GLEESIGLSRMVFINNIALAQIKNNNIDVAIENIEN--MLTSENQVMEPQYFGFAYLFRK
VLEEQLQPAVEK----------------------------------------ISIMAERL
ANQFAIYKPVTDFFLQLVEAGKVDDARALLQRCGAIAEQTSILLVFFIRNSRKPGKA---
-STLKSLIELIPELNEKQE

PF01535 // ENSGT00390000016775_0_Domain_20 (1520, 1548)

AYNSLMKSYASERDVTSAKALYEHLTAKNIKLNDLFLKRYA
FLLKSAGESVPFTEPPESFEFYAQQIKESKENSS----------

------------------------------------------------------------
---------MAALLRPARWLLRAGAVPGLPLPLRL-------LAGGPG--RPRVALCLPA
ACPGPAAGGLLSQARLYAI-AAEKKNYLQEEPT------SSHRRNASQFDWALMRLDNSV
RRTGRIPKTLLQKVFDNTCH-SGSPGGNQALLLLRSCGSLLPELKLSERTEFAHRIWDKL
QKLGTVYDVSHYNALLKVYLQNEYKFSPTDFLAKMEEANIQPNR

PF01535 // ENSGT00390000016775_0_Domain_6 (285, 314)

VTYQRLIAAYCNVGDI
EGASKILGFMKTK

ENSGT00390000016775_0_Linker_6_8 (314, 321)

DLPVTEA

PF01535 // ENSGT00390000016775_0_Domain_8 (321, 351)

VFSALVTGHARAGDMENAENILTV-MKEAG

ENSGT00390000016775_0_Linker_8_7 (351, 357)

IEPGPD

PF01535 // ENSGT00390000016775_0_Domain_7 (357, 384)

TYLA
LLNAYAEKGDIDHVKQTLEKVEKSDLYLMDRDLFQIIFSFSKAGYPQYVSEILEKITYER
RYIPDAMNLILLLVTEKLEDTALQILLACPISRE-------DGLNDFGSFFLRHCVTMDT
PVEKLKHYCKKLKDAQMHTSALQFTLQCALLANKPDLAKALMNALKEEGF-PVRTHYFWP
LLVGYQKEKNVQGVIEILKGMHEMGVNPDQETYVNYVFPCFDSVKSVRAVLQENGCLPES
N--VFSQAELKSEAVNGN----LDYILSFLESNTL-PFSFT-SLRGSLILGFR----RS-
------MNINL-WSKITELLYKDGRYCQEPLGPT-EAVGYFLYNLIDSMSDSEVQAKEEH
LRQYFHQLKEMNVKIPENIYRGIRNLLDNYHVPELIKNILHVIITFNENSKVYTYRTSKL
TISDLESTLEKLKAENQPVGDVLKQLILMLCSEENMQKALELKAKYESD-MAVGG

PF01535 // ENSGT00390000016775_0_Domain_11 (836, 871)

YAALI
NLCCRHDNAEDALNL-------------KQ

ENSGT00390000016775_0_Linker_11_12 (871, 888)

EFDRLDSSAVLDTNKYV

PF01535 // ENSGT00390000016775_0_Domain_12 (888, 914)

GLVKVLGKHGKLQ
DAINILKEMKEKDVLIKDATVLSFFHILNGAALRGETETVQQLHEAIVTLGLAKPSTTIS
SPLVTLYLEK-DDLPTALEVAIDC---HKKYKILPRIHDVLCKLI-EKGETDLIQKAMDF
VSQEQGEMTMLYDLFFAFLQTGN-YKEAKKIIETPGIRARPTRLQWFCDRCISSNQV---
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------

------------------------------------------------------------
---------MAALLRHVGCLFCAWIVAHLLLSLRL--------PAGPV--QLHATPGLLA
ALGGPMA--VVSQAKLYAT-PAEKKDHLQEQL------ISAHGRNVSQLNWALMRVDNSV
RRTGHITKTL-QKVFDSTYN-IGNPGSNQVLLLLYSCGSLLPELKFSEQTEFASRIWEKL
QKFDTGYDVSHYTALFKVYLQNEYKFSPSDFLAKMKETNLLPNRMTYQKLFTAY-NLKYI
EGASKILGFMKNKNLQITEAVFSALVTGHARAEDMENTENILTV-MKEARSEPSLDIYLA
LLNAYAEKGGIDHVKQTLEKVEKSDLYLMDRDLLQMIFNFSKAGYLH----VLEKVTYQR
RHFPDLMNLILLLITEKLEETAFQILLVYPVSRK--------NLRDFGSLFLRHCVALNI
PAEKLKDYCKKLKEAQMHTSPLHFTLYCAFLNKKMDLAKILMKALKEEAF--VRTHYFWP
LLIEHQKEKNVRGTIEVLKRIYEMGVNPDLEICVSY-FPSLHSVKSACAILQENGCLSET
N--TFLQTEFRSETVNGN----LGYLLSFLESNIL-HLQFT-SLRGSLISGFR----RS-
------MTINL-WSKIAELFVKGWKLLPGDSR-IKKTVGYFLHK-----GPAEVQAEEKC
LRQYFHQLKDVDVKIPQNIYRSI-NLLDIYHFPELRMLMFCL------RTL----KTLQQ
KLSDLEGTLKKHEAENQLIRNVLKQHIITLL-EETMENALELKVKYESD-MVVSDYAALI
KLCCLHGNAEDTLNL-------------KQ-----------------------------A
STVNILKEMEKKDVLTKYSKVSSFFHILNGPSLRRKVETAKQLHDAILTFGLAKPSTNLS
-PSVTLYLEK-DELAAL-EEAL---DFHEKYKVLPRIHDILCRLI-EKG---KIQKVINF
VSQEQGEILMLYDLFFTFLQTGN-FKEAKKIIKTLGIRACLSRHV------FQSNQVELV
EKFTNPWKKKVFECDRDQ

PF01535 // ENSGT00390000016775_0_Domain_13 (1099, 1128)

TYYNLLKLYKINGNCQSADAVWNKMQEENIISFVKTIWLLVE
ILR--NQEVPFD----VPELWYEDEK-QSLNS----LSTSCVENSLQRQPLNACPKKQSK
-DAY-IFLKVQSQSIKFTNGTYNGKII---------LQKQCVK-NVAETHVKSVTLDNAA
NSLLIIREVRKD----ALIMLKTTLNLEQIPSRLAVT-----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------

------------------------------------------------------------
---------MAALLRSSCWLLRAGAAPRLPLSLRLPLSLRLLTGG-PG--RPHAASYLPA
ARAGPAAGGLLSPARLYVI-AAEKKDI-QEES------TFSSRRIASHFDWALMRLDNSV
RRTGRIPKSLLQKVFDDTCRS-GGPGSSHALLLLRSCGSLLPELKLEDRTEFAH

PF13812 // ENSGT00390000016775_0_Domain_5 (235, 296)

RIWDKL
QKLGAVYDVSHYNALLKVYLQNEYKFSPTDFLAKMEEANIQPNRVTYQRLIASYC

ENSGT00390000016775_0_Linker_5_7 (296, 309)

NMGDI
EGASKILG

PF17177 // ENSGT00390000016775_0_Domain_7 (309, 417)

FMKTKDLPVTEAVFSALVTGHARAGDMENAENILTV-MRDAGIEPGPDTYLA
LLNAYAEKGDIDHVKQTLEKVEKSELHLMDRDLLQIIFSFSKAGYPQYVSEILEKVTCER
RYIPDAMNLILLLVTEKLEDVALQILLACPVSKE-------DGISDFGGFFLRHCVTMNT
PVEKLTDYCKKLKEVQMHSFPLQFTLHCALLAKKTDLAKALMKAVKEEGF-PIRTHYFWP
LLVGHQKEKNVQD----------------------EILPCWPSWSQT---------PNLS
D--MFSQAELRSEAVNGN----LDFVLSFCKYATL-NS------ISDYICFSL----LLL
----LQCTIFL-SYQITELLYKDGRYCQEPPGPT-EAVGYFLYNLIDSMSDSEVQAKEER
LRQYFHQLKEMNVKIPENIYRGIRNLLDSYHVPELIKVCEIA-----INWK----NTVRL
RSSELESRLETLKAENQPIRDVLKQLILTLCSQENMQKALELKAKYESD-MVISG

PF01535 // ENSGT00390000016775_0_Domain_11 (836, 871)

YAVLI
NLCCRHDNAEDALNL-------------KE

ENSGT00390000016775_0_Linker_11_12 (871, 886)

EFDRLDSSAVLDTSK

PF01535 // ENSGT00390000016775_0_Domain_12 (886, 914)

YVALVRVLAKHGRLQ
DAINILKEMKEKDVPIKDSTVLSFFHILNGAALRGEIETVKQLHEAIVTLGLAKPSTNIS
FPLVTVYLEK-DDVSAALDVAIDC---CEKYKILPRMHDILCKLI-EKGETDLIQKAMDF
VSQEQGEMMMLYDLFFAFLQTGN-YKEAKKIIETPGIRARSTRLQWFCDKCVANNQVETL
EKLVE-LTQKLFECDRDQMYYNLLKLYKMNGDWQRADAVWNKIQEENIIPREKTLRLLAE
ILRDGNQEVPFD----VPELWYEDEK-HSLNSSLDSSSDSTTEPGFQKDILNACRLKQSK
-GAYDIFLKAKQQNVVFNAETYSDLIKLLLSKEYF-TQAVEVK-AFAETHIKGFTLNDAA
NSLLIITQVRRDYLKEALRTLKTALDQQQTPSKVAVTRLIQALAMKGDVENIEVVQKMVN
GLEDSLGLSKMVFINNIALAQIKNNNIDVAIENIEN--MLTSENQVIEPQFFGLAYLFRK
VIEEQLEPAVEK----------------------------------------ISIMAERL
ANQFAIYKPVTDFFLQLVDAGKVDDARALLQRCGAIAEQTPILLLFFLRNSGKQGKA---
-STLKSLLELIPELNEKEEAYSSLMKSYVSEKDVTSAKALYEHLTAKNVKLNDLFLKRYA
VLLKNAGESVPFTEPPESFEFYVQQLKELRENSS----------

------------------------------------------------------------
---------MAALLRSSCWLLRAGAAPRLPLSLRL------LTGG-PG--RPHAASYLPA
ARVGPVAGGLLSPARLYVI-AAEKKDI-QEES------TFSSRRIANHFDWALMRLDNSV
RRTGRIPKSLLQKVFDDTCRS-GGPGSSHALLLLRSCGSLLPELKLEERTEFAH

PF13812 // ENSGT00390000016775_0_Domain_5 (235, 294)

RIWDKL
QKLGAVYDVSHYNALLKVYLQNEYKFSPTDFLAKMEEANIQPNRVTYQRLIAS

ENSGT00390000016775_0_Linker_5_7 (294, 309)

YCNTGDI
EGASKILG

PF17177 // ENSGT00390000016775_0_Domain_7 (309, 417)

FMKTKDLPVTEAVFSALVTGHARAGDMENAENILTV-MRDAGIDPGPDTYLA
LLNAYAEKGDIDHVKQTLEKVEKSELHLMDRDLLQIIFSFSKAGYPQYVSDILEKVTCER
RYIPDAMNLILLLVTEKLEDVALQILLACPVSKE-------DGISDFGGFFLRHCVTMNT
PVEKLTDYCKKLKEVQMHSFPLQFTLHCALLAKNTDLAKALMKAVKEEGF-PIRTHYFWP
LLVGHQKEKNVQGIIEVLKGMQELGVHPDQETYVDYVIPCFSSVKSARAILQENGCLSNS
D--TFSQAELRSEAVNGN----LDFVLSFLESNTL-PLSLQ-SIRSSLLLDYI----CFC
LLLLLQCTIFL-SYQITELLYKDGRYCQEPPGPT-EAVGYFLYNLIDSMSDSEVQAKEER
LRQYFHQLKEMNVKIPENIYRGIRNLLDSYHVPELIKDAYMLVDSEDLDSR----KTLRL
RSSELESRLETLKAEDQPIRDVLKQLILALCSQENMQKALELKAKYESD-MVISG

PF01535 // ENSGT00390000016775_0_Domain_11 (836, 871)

YAALI
NLCCRHDNAEDALNL-------------KE

ENSGT00390000016775_0_Linker_11_12 (871, 888)

EFDRLDSSAVLDTSKYV

PF01535 // ENSGT00390000016775_0_Domain_12 (888, 914)

GLVRVLAKHGKLQ
DAINILKEMKKKD

ENSGT00390000016775_0_Linker_12_13 (914, 1099)

VPIKDSTVLSFFHILNGAALRGEIETVKQLHEAIVTLGLAKPSTNIS
FPLVTVYLEK-DDLSTALDVAIDC---CEKYKILPRMHDILCKLI-EKGETDLIQKAMDF
VSQEQGEMMMLYDLFFAFLQTGN-YKEAKKIIETPGIRARSTRLQWFCDKCIANNQVETL
EKLVE-LTQKLFECDRDQ

PF01535 // ENSGT00390000016775_0_Domain_13 (1099, 1128)

MYYNLLKLYKMNGDWQKADAVWNKIQEENIIPREKTLRLLAE
ILRDSNQEVPFD----IPELWYEDEK-HSLNSSSDSSSDSTTEPDFQKDILNACRLKQSK
-GAYGIFLKAKQQNVVFNAETYSDLIKSLLSKEYF-TQAVEVK-AFAETHIKGFTLNDAA
NSLLIITQVRRDYLKEALRTLKTALDQQQTPSKVAVTRLIQALAMKGDVENIEVVQKMVN
GLEDSLGLSKMVFINNIALAQIKNNNIDVAVENIEN--MLTSENQVIEPQFFGLAYLFRK
VIEEQLEPAVEK----------------------------------------ISIMAERL
ANQFAIYKPVTDFFLQLVDAGKVDDARALLQRCGAIAEQTPILLLFFLRNSGKQGKV---
-LWVGECVTEP----SPFEKFFIVLSLSVSKKDVTSAKALYEHLTAKNAKLNDLFLKRYA
VLLKNAGESVPFTEPPESFEFYVQQLKESRENSS----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------VW
IPVIS-----------------------QSLLLIQDFFSHLPSLI-SQGES--YTQTMDF
RA------RVFFSFVFVFLSCPPKFQDMSVLIK-------------VDLSLNLTFKVETL
EKLVE-LTQKLFECDRDQ

PF01535 // ENSGT00390000016775_0_Domain_13 (1099, 1128)

MYYNLLKLYKMNGDWQKADAVWNKIQEENIIPREKTLRLLAE
ILRDSNQEVPFD----VPELWYEDEK-HSLNSSSDSSSDSTTEPDFQKDILNACRLKQSK
-GAYGIFLKAKQQNVVFNAETYSDLIKLLLSKEYF-TQAVEVK-AFAETHIKGFTLNDAA
NSLLIITQVRRDYLKEALRTLKTALDQQQTPSKVAVTRLIQALAMKGDVENIEVVQKMVN
GLEDSLGLSKMVFINNIALAQIKNNNIDVAVENIEN--MLTSENQVIEPQFFGLAYLFRK
VIEEQLEPAVEK----------------------------------------ISIMAERL
ANQFAIYKPVTDFFLQLVDAGKVDDARALLQRCGAIAEQTPILLLFFLRNSGKQGKA---
-STLKSLLELIPELNEKEE

PF01535 // ENSGT00390000016775_0_Domain_20 (1520, 1544)

AYSSLMKSYVSKKDVTSAKALYEHLTAKNAKLNDLFLKRYA
VLLKNAGESVPFTEPPESFEFYVQQLKESRENSS----------

------------------------------------------------------------
---------MAALLRSSCWLLRAGAAPRLPLSLRL------LTGG-PG--RPHAASYLPA
ARVGPVAGGLLSPARLYVI-AAEKKDI-QEES------TFSSRRIANHFDWALMRLDNSV
RRTGRIPKSLLQKVFDDTCRS-GGPGSSHALLLLRSCGSLLPELKLEERTEFAH

PF13812 // ENSGT00390000016775_0_Domain_5 (235, 294)

RIWDKL
QKLGAVYDVSHYNALLKVYLQNEYKFSPTDFLAKMEEANIQPNRVTYQRLIAS

ENSGT00390000016775_0_Linker_5_7 (294, 309)

YCNTGDI
EGASKILG

PF17177 // ENSGT00390000016775_0_Domain_7 (309, 417)

FMKTKDLPVTEAVFSALVTGHARAGDMENAENILTV-MRDAGIDPGPDTYLA
LLNAYAEKGDIDHVKQTLEKVEKSELHLMDRDLLQIIFSFSKAGYPQYVSEILEKVTCER
RYIPDAMNLILLLVTEKLEDVALQILLACPVSKE-------DGISDFGGFFLRHCVTMNT
PVEKLTDYCKKLKEVQMHSFPLQFTLHCALLAKNTDLAKALMKAVKEEGF-PIRTHYFWP
LLVGHQKEKNVQGIIEVLKGMQELGVHPDQETYVDYVIPCFSSVKSARAILQENGCLSNS
D--TFSQAELRSEAVNGN----LDFVLSFYFPY---------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------

------------------------------------------------------------
---------MAALLRPAGRLFRAGASARLPLSLRL-------LAGGPS--WLHAASGLPA
ARAVPVARELVTQARLYAT-ATEKKDHLQEEP------ISAHRRNASQFDWALTRLDNSV
R-TGRIPKALLK-VFD-KTHS-GNPGANQALLLLRSCGSLLPELKLSERTEFAHRIWDKL
QKLGTVYDV

PF01535 // ENSGT00390000016775_0_Domain_5 (250, 284)

SHYNALLKVYLQNEYKFSPTDFLAKMEEANIQPNRVTYQRLIAAYCNVGDI
EGASKILGFMKNKDLPVTE

PF01535 // ENSGT00390000016775_0_Domain_8 (320, 355)

AVFSALVIGHARAGDMENAENILTV-MKEAGIEPG

ENSGT00390000016775_0_Linker_8_7 (355, 356)

P

PF01535 // ENSGT00390000016775_0_Domain_7 (356, 390)

DTYLA
LLNAYAEKGDIDHVKQTLEKVEKSDLYLMDRDLLQVIFSFSKAGYPQYVSDILEKITYEK
RYIPDAMNLILLLITEKLQDTALQILLACPVSRE-------DNLSDFGNFFLQHCVTMNT
PAEKLKDYCKRLKEAQMHTSPFQFTLYCALLNNKMDLAKALMKALKEEGF-PIRT

PF01535 // ENSGT00390000016775_0_Domain_10 (536, 570)

HYFWP
LIIGHQKEKNVQGIIEVLKAMHEMGVNPDQETYVNYVFPFFDSVKSAYAILRENGCLSES
---TFLQAQFRSEVLNGN----LDYVLSFLESNTL-PFPFK-SLRGSLSLGFR----RS-
------MNINL-WSKITELLYKDERYCQEPSG-T-ETVGYFLYNLIDSMSDLEVQAKEEH
LRQYFHQLKHMNIKIPENIYRGIRNLLDSYHVPELIKDVSILVEREKTDSQ----KSQ-H
TSSDLEAMLEKLKAENQPIGDVLKQFIVALCSEQNMQKALEVKAKYESD-MVPGGYAALI
NLCCRHDNAEDALNL-------------KQEXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XAINILKEMKEKDVLIKDSTVLSFFHILNDAALRGEVETVKQLHEAIVTLGLAKPSTTIS
SPLVTLYLEK-DDLPAALEVAIDC---CEKYKILPRIHDILCKLI-EKGNTDLIQKXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XX-XX--XXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXX----XXXXXXXXXX-XXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXX
-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXX-XXAEIHIKGFTLNGAA
NSLLIATQVRRDYLKEALTTLKTTLNLEQIPSKTAVTRLIQALALKGDVESIQMIQKMVK
GLEDSIGLSHMVFINNIALAQMKN-NIDVAI-EIES--MLTSGNQTVDPRYFGLAYLFRK
VIDGQLEPALEK----------------------------------------ISIMAERL
ANHFAVYKPVTDLFLQLVDSGKVDDARALLQRCSAIAEQIPILLVFCIRSSRKPGKA---
-PTMKSLLELIPELIEKE

PF01535 // ENSGT00390000016775_0_Domain_20 (1519, 1553)

EAYGSIMSNYALDNDVASAKALYEHLTAKNIKLNDLFLKQYA
VLLKKAGESVPFTEPPESFAFYAKQLKELKESAL----------

MSITLTPLFSEKCGFPSSNLKRSLAPPTFGAPCSWSLPRRATLR-----SRAPPVLLAER
ASCCGDVRAMAALLRSSCWLLRAGAAPRLPLSLRL------LTGG-PG--RPHAASYLPA
ARAGPVAGGLLSPARLYVI-AAEKKDI-QEES------TFSSRRIASHFDWALMRLDNSV
RRTGRIPKMLLQKVFDDTCRS-GGPGSSHALLLLRSCGSLLPELKLEERTEFAH

PF13812 // ENSGT00390000016775_0_Domain_5 (235, 296)

RIWDKL
QKLGAVYDVSHYNALLKVYLQNEYKFSPTDFLAKMEEANIQPNRVTYQRLIASYC

ENSGT00390000016775_0_Linker_5_7 (296, 309)

NMGDI
EGASKILG

PF17177 // ENSGT00390000016775_0_Domain_7 (309, 417)

FMKTKDLPVTEAVFSALVTGHARAGDMENAENILTV-MREAGIEPGPDTYLA
LLNAYAEKGDIDHVKQTLEKVEKSELHLMDRDLFQIIFSFSKAGYPQYVSEILEKVTCER
RYIPDAMNLVLLLVTEKLEDVALQILLSCPVSKE-------DGISDFGSFFLRHCVTMNT
PVEKLTDYCKKLKEIQMHSFPLQFTLHCALLAKKTDLAKALMKAVKEEGF-PIRTHYFWP
LLVGHQKEKNVQGIIEVLKVMQELGVPPDRETYIGYVIPCFNSIKSARAILQENGCLSNS
D--TFSQAELRSEAINGN----LDFVLSFLESNTL-PLSLQ-SIRSSLLLGFR----RS-
------MNINL-WSKITELLYKDGRYCQEPPGPT-EAVGYFLYNLIDSMSDSEVQAKEER
LRQYFHQLKEMNVKIPENICKGIRNLLDSYHVPELIKDAYMLVDSENLDSQ----KTLRL
RSSELESRLETLKAEDQPIRDVLKQLIVALCSQENMQKALELKAKYESD-MVISG

PF01535 // ENSGT00390000016775_0_Domain_11 (836, 871)

YAALI
NLCCRHDNAEDALNL-------------KE

ENSGT00390000016775_0_Linker_11_12 (871, 888)

EFDRLDSSAVLDTSKYV

PF01535 // ENSGT00390000016775_0_Domain_12 (888, 914)

GLVRVLAKHGRLQ
DAINILKEMKKKDVPIRDSTVLSFFHILNGAALRGEIETVKQLHEAIVTLGLAKPSTNIS
FPLVTVYLEK-DDLSTALDVAIDC---CEKYKILPRMHDILCKLI-EKGETDLIQKAMDF
VSQEQGEMVMLYDLFFAFLQTGN-YKEAKKIIETPGIRARSTKLQWFCDKCIANNQVETL
EKLVE-LTQKLFECDRDQMYYNLLKLYKMNGDWQRADAVWNKIQEENIIPRGKTLRLLAE
ILRDGNQEVPFE----VPE-WYEDEK-HSLNSSLDSSSDSTTEPDFQKDILNACQLKQNK
-EAYGIFLKAKQQNVVFNAETYSDLIKLLLSKEYF-TQAVEVK-AFAETHIKGFTLNDAA
NSLLIITQVRRDYLKEALTTLKTALDQQQTPSGIAVTRLIQALAMKGDVENIEVVQKMVN
GLEDSIGLSKMVFINNTALAQIKNNNIDVAIENIEN--MLTSENPVIERQYFGLAYLFRK
VIEEQLEPAVEK----------------------------------------ISIMAERL
ANQFAIYKPVTDFFLQLVDAGKVDDARALLQRCGAIAEQTSILLVFFLRNSGKRGKA---
-STLKSLLELIPELNEKEEAYSSLMKSYASEKDVTSAKALYEHLTAKNTKLDDLFLKRYA
VLLKNAGESVPFTEPPESFEFYVQQVKELRENSS----------

------------------------------------------------------------
---------MAAL--RARW--RAGAAGRLPLSLRL-------LAGCPA--RPHAAPCLPT
ARAGPAAGGLLSQARLYAI-AAEKK-DLPEEPT------HCYRRNASQFDWALMRLDNSV
RRTGRIPKTLLQKVFDNTCR-SGSPGGNQALLLLRSCGSLLPELKLAERTEFAHRIWDKL
QKLXXXXXXXXXXXXXXXXXXXXXXXXPTDFLAKMEEANIQPNR

PF01535 // ENSGT00390000016775_0_Domain_6 (285, 319)

VTYQRLIAAYCNVGDI
EGASKILGFMKTKDLPVTEAVFSALVTGHARAGXXXXXXXXXXX-XXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------XXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPVRTHYLLA
LLVGHQKEKNVQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXENGCLPES
N--TFTYAELKSEAINGN----LDYILSFLESNTL-PFSFN-TLRGSLILGFR----RS-
------MDINL-WSKITELLYKDGRYCQEPPGPT-EAVGYFLYNLIDSMSDSEVQAKEER
LRQYFHQLKEMNVKIPENIYRGIRNLLDSYHVPELIKDVNMLVEREKIDSR----KTVQF
TSSDLESQLEKLKAENQPIGDVLKQLILVLCSEENMQKALELKAKYESN-MVV

PF01535 // ENSGT00390000016775_0_Domain_11 (834, 881)

GGYAALI
NLCCRHDNAEDALSL-------------KQEFDRLDSSAVLDTNKYVSLVRVLGKHGKLQ
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXX-DDLPIPLQVTLNC---YEKCNILPRIHDVLCKLI-EKGETDLIQKXXXX
XXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXTPGIRARPSRLQWFCDRCITSNQVETL
EKLVE-LTQKLFECDRDQMYYSLLKLYXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXX----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXAETHIKGFTLNDAA
NSLLIITQVRRDYLKEAQTTLKTALNLEQIPSRIAVTRLIQAFASKGDVQSIEAIQKMVN
GLEDSIGLSRMVFINNIALAQIKNNDIDVAIENIEN--MLTSGTQTMEARYFGLTYLFRK
VIEEQLEPAVEK----------------------------------------LSIMAERL
ANQFAVYKPVTDLFLQFVDSGKTDDAKALLQRCSAIAEQTPVLLLFCTRCSRKPGKA---
-AALKSLLELIPEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNAL----------

------------------------------------------------------------
---------MAALLRPARWLLRAAAAPYLPLSLRL-------LAGGPG--RPHAALCLRA
ARARPVAGGLLSQARLHSI-AAEKKNYLQEEPT------SSHRRNASQFDWALMRLDNSV
RRTGRIPKTLLQKVFDNTCH-SGSAGGNQALLLLRSCGSLLPELKLSERTEFAHKIWDEL
QKLGTVYDVSHYNALLKVYLQNDHKFSPTDFLAKMEKGNIQPNR

PF01535 // ENSGT00390000016775_0_Domain_6 (285, 314)

VTYQRLIAAYCNMGDI
EGASTILGFMKTK

ENSGT00390000016775_0_Linker_6_8 (314, 321)

DLPVTEA

PF01535 // ENSGT00390000016775_0_Domain_8 (321, 351)

VFSALVTGHARSGDMENAENILTV-MKEAG

ENSGT00390000016775_0_Linker_8_7 (351, 357)

IEPGPD

PF01535 // ENSGT00390000016775_0_Domain_7 (357, 384)

TYLA
LLNAYAEKGDIDHVKQTLEKVEKSDLYLMDRDLLQIILSFSKAGYPQYVPEILEKITYER
RYIPDTMNLILLLVTEKLEDTALQILLACPISRE-------SSQNDFGSFFLRHCVTMNT
PAEKLEDYCKKLKEAQLHTSPLQFTLQCALVAQKLDLAKVLMKALKEEGF-PIRTHYFWP
LLVGHQKEKNVQGIVEVLKGMHEIGVTPDQETYVNYVFPCFDSIKSVRAVLQENGCPHDD
N--VFSQAELRSKAVNGN----LDYILSFLESNTL-PFSFS-SLRGSLILGFR----RS-
------MNINL-WSKITELLYKDGRYCQEPPGPT-EAVGYFLYNLIDSMSDSEVQAKEEH
LRQYFHQLKEMNVKIPENIYRGIRNLLDSYHVPELIKDVNILVEREK--TDSRKISALQP
SSSDLESKLEKLKAENQPIGDILKQLILMLCSEENMQKALELKAKYESD-MVVGG

PF01535 // ENSGT00390000016775_0_Domain_11 (836, 871)

YAALI
NLCCRHDNAEDALNL-------------KR

ENSGT00390000016775_0_Linker_11_12 (871, 889)

EFDRLDSSAVLDTGKYVR

PF01535 // ENSGT00390000016775_0_Domain_12 (889, 914)

LVKVLGKHGKLQ
DAINILKEMKEKD

ENSGT00390000016775_0_Linker_12_13 (914, 1100)

VLVKDATVLSFFHILNGAALRGETETVKQLHEAIVTLGLAKPSTTLS
SPLVTLYLEK-DDLPAALESTIDC---YEKYKILPRIHDVLCKLI-EKGETELIQKAMDF
VSQEQGEMTMLYDLFFAFLQTGN-YKEAKKIIETPGIRARPTRLQWFCDRCIANNQVETL
EKLVE-MTQKLFECDRDQL

PF01535 // ENSGT00390000016775_0_Domain_13 (1100, 1128)

YYSLLKLYKVNDDWQKADAVWNKMQEENIIPREKTLRLLAE
ILRNNNQEVPFD----VPELWYEEEK-DCPT-----SLPSPVEVNLQQGLLNACHRRRNK
-DAFNIFLTAKKQNIVFDNETYARLINLLLMKDNS-TQAMQVK-DFAETHIKGFTLNDAA
NSLLIITQVRRDYLKDALTTLKTALDLDQIPSRLAVTRLIQACALKGDTESIHDIQKLVN
GLEDSIGLSRMVFINNIALAQIKNNNIDVAIESIEN--MLTSENQTVDPQYFGLAYLFRK
VIEGQLEPALEK----------------------------------------ISIMAERL
ANQFAVYKPVTDLFLQLVDSGKVDDARALLQRCGAIAEQMPILLVFCIRNSQRPGKA---
-PVMKSLLELIPELIDKEEAYTCLMKSYVFDNDVTSAKALYESLTAKNVKLNDLFLKRYA
VLLKNAGESVPFTEPPESFEFYAKQLKESKETHL----------

------------------------------------------------------------
---------MAALLRPARWLLGAAAAPRLPLSLRL-------PAGVPG--RLSSVVRVAA
VGSRPAAGELLSQARLYAI-VAE-KRDLQEEPA-------PVRKNSSQFDWALMRLDNSV
RRTGRITKGLLQRVFESTCS-SGSPGSNQALLLLRSCGSLLPELSLPERTEFAHKIWDKL
QELGVVYDVSHYNALLKVYLQNEYKFSPTDF

PF13812 // ENSGT00390000016775_0_Domain_6 (272, 315)

LAKMEGANIQPNRVTYQRLIAAYCNVGDI
EGASKILGFMKTKD

ENSGT00390000016775_0_Linker_6_7 (315, 322)

LPITEAV

PF13812 // ENSGT00390000016775_0_Domain_7 (322, 365)

FSALVTGHARAGDMENAENILTV-MKQAGIEPGPDTYLA
LLNAHAERGDIGQVRQILEKVEKSDHYFMDRDFLQVIFSFSKAGYPQYVSEILEKITCERRSIPDAMNLILFLATEKLEDTAFQVLLALPLSKD-------ESSDNFGSFFLRHCVTLDLPPEKLIDYCRRLRDAKLHSSSLQFTLHCALQANRTALAKAVMEALREEGF-PVRPHYFWPLLAGHQKTKNVQGIIDILKIMNEMGVDPDQDTYINYVFPCFDNAQSVRAALQENECLLASS--TFAQAEVKNEAINGN----LQNILSFLESNTL-PFSFS-SLRNSLILGFR----RS-------MNIDL-WSKITELLYKDERYCSKPPGPA-EAVGYFLYNLIDSMSDSEVQAKEERLRQYFHQLQEMNVKVPENIYKGICNLLNTYHVPELIKDIKVLVDREKVDSQ----KTSQVTASDLESTLEKLKAEGQPVGAVLKQLLLLLCSEENMQKALEVKAKYESD-MVIGGYAALINLCCRHDNAEDAWNL-------------KQEVDRLDPSAILDTAKYIALVKVLGKHSRLQDAINILKEMKEKDVVIKDATVLSFFHILNGAALRGEIETVKQLHEAIVTLGLAKPSSNISFPLVTVHLEK-GDLPAALEASIAC---HKKYKVLPRIHDVLCKLV-EKGETDLIQKAMDFVSQEQGEMTMLYDLFFAFLQTGN-YKEAKKIIETPGIRARPTRLQWFCDRCIASNQVEALEKLVE-LTEKLFECDRDQMYYNLLKLYKISSDWQRADAVWTKMQEENIIPRERTLRLLAEILKTSNQEVPFD----VPELWFGDDR-PSLS---P-SSPSAGEDVTEKTLLSNCRLKKNK-DAYNIFLKAEKQNVVFSSETYSTLIGLLLSKDDF-TQAMHVK-DFAETHIKGFTLNDAANSLLIIRQVRRDYLKGALATLRAALDLEQVPSQIAVTRLIQALALKGDVESIEAIQRMVTGLD-TIGLSKMVFINNIALAQMKNNKLDAAIENIEH--LLASENQAIEPQYFGLSYLFRKVIEEQMEPALEK----------------------------------------LSIMSERMANQFALYKPVTDLFLQLVDSGKVDEARALLERCGAIAEQSSLLSVFCLRTSQKPKKA----PVLKTLLELIPELRDNDKVYSCSMKSYALDKDVASAKALYEYLTAKNLKLDGLFLKRYAA

PF13812 // ENSGT00390000016775_0_Domain_8 (322, 365)

FSALVTGHARAGDMENAENILTV-MKQAGIEPGPDTYLALLNAHAERGDIGQVRQILEKVEKSDHYFMDRDFLQVIFSFSKAGYPQYVSEILEKITCER
RSIPDAMNLILFLATEKLEDTAFQVLLALPLSKD-------ESSDNFGSFFLRHCVTLDL
PPEKLIDYCRRLRDAKLHSSSLQFTLHCALQANRTALAKAVMEALREEGF-PVRPHYFWP
LLAGHQKTKNVQGIIDILKIMNEMGVDPDQDTYINYVFPCFDNAQSVRAALQENECLLAS
S--TFAQAEVKNEAINGN----LQNILSFLESNTL-PFSFS-SLRNSLILGFR----RS-
------MNIDL-WSKITELLYKDERYCSKPPGPA-EAVGYFLYNLIDSMSDSEVQAKEER
LRQYFHQLQEMNVKVPENIYKGICNLLNTYHVPELIKDIKVLVDREKVDSQ----KTSQV
TASDLESTLEKLKAEGQPVGAVLKQLLLLLCSEENMQKALEVKAKYESD-MVIGGYAALI
NLCCRHDNAEDAWNL-------------KQEVDRLDPSAILDTAK

PF01535 // ENSGT00390000016775_0_Domain_12 (886, 914)

YIALVKVLGKHSRLQ
DAINILKEMKEKDVVIKDATVLSFFHILNGAALRGEIETVKQLHEAIVTLGLAKPSSNIS
FPLVTVHLEK-GDLPAALEASIAC---HKKYKVLPRIHDVLCKLV-EKGETDLIQKAMDF
VSQEQGEMTMLYDLFFAFLQTGN-YKEAKKIIETPGIRARPTRLQWFCDRCIASNQVEAL
EKLVE-LTEKLFECDRDQMYYNLLKLYKISSDWQRADAVWTKMQEENIIPRERTLRLLAE
ILKTSNQEVPFD----VPELWFGDDR-PSLS---P-SSPSAGEDVTEKTLLSNCRLKKNK
-DAYNIFLKAEKQNVVFSSETYSTLIGLLLSKDDF-TQAMHVK-DFAETHIKGFTLNDAA
NSLLIIRQVRRDYLKGALATLRAALDLEQVPSQIAVTRLIQALALKGDVESIEAIQRMVT
GLD-TIGLSKMVFINNIALAQMKNNKLDAAIENIEH--LLASENQAIEPQYFGLSYLFRK
VIEEQMEPALEK----------------------------------------LSIMSERM
ANQFALYKPVTDLFLQLVDSGKVDEARALLERCGAIAEQSSLLSVFCLRTSQKPKKA---
-PVLKTLLELIPELRDNDKVYSCSMKSYALDKDVASAKALYEYLTAKNLKLDGLFLKRYA
ALLKDVGEPVPFPEPPESFAFYIKQLKEARESPS----------

------------------------------------------------------------
---------MAALLRPARWLLGASVAPRLPLSLRL-------LAGGPG--RLCPVPRVAA
AGGRRPAGEQLSQARLYAI-VAE-KRDLQEEPA-------PVRR--SQFDWALMRLDNSV
RRTGRITKGLLQRVFESTCR-SGSPGGNQALLLLRSCGSLLPELSLAERTEFAH

PF13812 // ENSGT00390000016775_0_Domain_5 (235, 295)

KIWDKL
QKLGTVYDVSHYNALLKVYLQNEHKFSPTDFLAKMEGANVQPNRVTYQRLIAAY

ENSGT00390000016775_0_Linker_5_7 (295, 308)

CDAGDI
EGASKIL

PF17177 // ENSGT00390000016775_0_Domain_7 (308, 417)

GFMKTKDLPITEAVFSALITGHARAGDMENAENILTV-MKEAGIEPGPDTYVA
LLNAYAEKGDIDHVKQILEKVEKSDHYLMDRDLLQIIATFSKAGYPQYVSEILEKISYER
RYIPDAMNLILLLVTEKLEDTALQILLALPVSKE-------ESGNVFGSFFLRHCVTVNT
PVEKLVDYCKKLKEARLHDSSLQFTLHCALLAKNTALAKAVMQALREEGL-PIRTHYFWP
LLAGHQKTKNVQGIMDILKIMSELGVNPDQDTYIQYVFPCFDNAESVRAALQENECLPTS
N--KFAQAEVRNEAINGN----LRNILSFLESNAV-PLSFS-SLRRSLIL----------
-----------------ELLYKSGRYCREPPGK---AVGYFLYNLIDSMRDSEVQAKEEH
LRQYFHQLKEMNVKVPENIYRGIRNLLDNYHVPELIKDVKVLVDKEKVDSR----KTSQL
TSSDLESTLENLKAKNQPLGDVLKQLLLLLCSEENMQKALEVKAKYESD-MVIGG

PF01535 // ENSGT00390000016775_0_Domain_11 (836, 871)

YAALI
NVCCRNDNAEDALNL-------------KQ

ENSGT00390000016775_0_Linker_11_12 (871, 888)

EFDRLDPSAVLDTAKYL

PF01535 // ENSGT00390000016775_0_Domain_12 (888, 914)

GLVKVLAKHGKLQ
DAINILKEMKEKG

ENSGT00390000016775_0_Linker_12_13 (914, 1099)

VVIKDATV-SFFHILNGAAFRGEIETVKQLHEAIVTLGLAQPSTSIS
TPLVTVHLEK-GDLPAALEASIEC---HGKYKILPRIHDVLCKLI-EKGETDLIQKAMDF
VSQEQGEMTMLYDLFFAFLQTGN-YKEAKKIIETPGIRARPTRLQWFCDRCISNNQVETL
EKLVE-LTQKLFECDRDQ

PF01535 // ENSGT00390000016775_0_Domain_13 (1099, 1128)

MYYSLLKLHKINGDWQRADAVWNKMQEENIIPRERTLQLLAE
ILKNSNQEVPFD----VPELWFEDDR-TSLS---S-SSPSAIETNTEKMLLKACRLRKSK
-DAYNVFLRAQKQNIVFSSEAYSTLIGLLLRKDSF-TQAMQVK-DFAETHIKGFTLNDAA
NSLLIITQVRRDYLKAALETLKAALDLEQIPSKVAVTRLIQAFALKGDLESIEAIQKMVN
GLN-MVGLSSMVFINNIALAQMKNNNIGVAIENIEH--LLSSESQTLEPQYFGLSYLFRK
VIEEQMEPALEQ----------------------------------------LSIMSERL
ANQFALYKPVTDLFLQLVDSGKVDEAKALLERCGAIAEQSPILSVFCLRSAQKPGKA---
-PVLKTLLELIPELREKREAYSCSMKSFVLDKDVASARALYEYLTAKNEKLDELFLKRYA
TLLKEVGEPVPFAEPPESFEFYVRQLKEARESPS----------

------------------------------------------------------------
---------MAALLRSSRWLLRAGAASRLPFSFRL-------LAGGPG--RLHPVPCLPA
ASAGPAAGDLASRARQYAAIAAKEQNDLQEES------ASARGKNVGQFEWALMRLDDSV
RRTGRIPKTLLEKIFMNTCHSVGTPGSNQVLLLLRSCGSLLPELTHSERTEFVHRIWDQL
QKLGTTYDI

PF01535 // ENSGT00390000016775_0_Domain_5 (250, 284)

SHYNALLKVYLQNEYKFSPTDFLAKMEEANIQPNRVTYQRLIAAYCNVGDI
EGASKILGFMKSKDLPVTE

PF01535 // ENSGT00390000016775_0_Domain_8 (320, 355)

AVFSALVTGHARAGDMENAENIITV-MKEAGIEPG

ENSGT00390000016775_0_Linker_8_7 (355, 356)

P

PF01535 // ENSGT00390000016775_0_Domain_7 (356, 390)

DTYLA
LLNAYAEKGDIDRVKQTLEKVKKSDIYLMDRDLLQVIFAFSKAGYPQYVSEILEKMTYEG
RYIPDAMNLILLLVTEKMEDTALEILLACPAPRK-------ENLSDFGSFFLQHCVTMNT
PAEKLQDYCKKLKAAQMHSCPLQFTLHCALSARKADLAKALMEALKEEDF-PVRA

PF01535 // ENSGT00390000016775_0_Domain_10 (536, 570)

HYFWP
LLAGHQKEKNVQGIIEVLKGMHEVGINPD

ENSGT00390000016775_0_Linker_10_11 (570, 834)

QDTYITYVFPCFDSVKSARTVLQENGCPVDN
G--TFSQAELRSEALNGN----LDFVLSFLKSNTS-HFSYL-YLRGSVILAFR----RC-
------VDINL-WSKITELFYKDKRYYLDHQGPTAEAVGYFLYTLIDSMSDSEVQAKEEC
LRQYFHQLKKMNITISQNIYRGIRNILDSYRVPELIKDVNVLIEVEKTDSE----KTSQL
KSSDLESKLENLKAENQPIRDTLRQLILVLCSEENMQKALEIKAKYESD-MVV

PF01535 // ENSGT00390000016775_0_Domain_11 (834, 881)

SGYAALI
GLCCRHDNVEDALNL-------------KQEFDRLDSTAV

ENSGT00390000016775_0_Linker_11_12 (881, 884)

LDT

PF01535 // ENSGT00390000016775_0_Domain_12 (884, 918)

RKYTELVKVLEKHGKLQ
DAVNILKEMKEKDVVVT

ENSGT00390000016775_0_Linker_12_13 (918, 1098)

DGTILSFFHILNGAALRGEVETVKQLHETIVTSGLAKPSIAIS
SPLVTVYLEN-NKVEASLQCSFSVYDTYRNYFYLPRFWDVVAKVCEEKGESDLIQKVMDF
VSHEQGEMMMLYDLFFAFLQMGN-YKEAKKIIETPGIRARHGRLQWFCDRCIASNQVETL
EKLVE-LTQKLFECDRD

PF01535 // ENSGT00390000016775_0_Domain_13 (1098, 1132)

QLYYNLLRLYKMNGDWQRADVVWNKIQEENIIPREKTLRLLAE
IFSNANQEVPFD----VPELWYEDKT-HGQIV----LSPSHEETDLQNEMLKACQRKDSK
-GAYDIFLKAQNQDTVFCSEAYRTLVKLLLVDG-Y-TDAMEVK-QAAETHIKGFTLNEAA
NSLLILAQVRRDYLKEALTVLRTALDLGQLPSRMAVTRLIQAFGLKGDVESIQTIQTMVK
GLEHTIGLSRMIFINNIALAQIKSNNIDVAVENIES--MLTSENSPVEPQYFGLTYLFRK
VIEEQLEPALEK----------------------------------------ISIMAERL
ANQFAVYKPVTDLFLQLVDSGKVDDARALLQRCGAIAEQTSVLSAFCIRKSQTPGQT---
-PTLKSLTELIPELKEKE

PF01535 // ENSGT00390000016775_0_Domain_20 (1519, 1553)

AAYTSIIRSYALDSDVASAKALYEHLTARNVKLNDLFLKRYA
VLLSSAGEPVPFTEPPESFEFYTKQLKESKEDPL----------

------------------------------------------------------------
---------MAALLRPARWLLGATAAPRLPLSLRL-------FAGCPG--RLFSVARVAA
AGSRPPAGELPSQARLYAI-VAE-KRDLQEEPA-------PVRRNNSQFDWALMRLDNSV
RRTGRITKGLLQKVFDSTCR-SGSPGGNQALLLLRSCGSLLPELSLAERTEFAHKIWDKL
QTLGTVYDVSHYNALLKVYLQNEHKFSPTDFLAKMERANIQPNRVTYQRLIAAYCDVGDI
EGASKILGF

PF17177 // ENSGT00390000016775_0_Domain_7 (310, 417)

MKTKDLPITEAVFSALVTGHARAGDMENAENILTV-MKEAGIEPGPDTYLA
LLNAYAEKGDIDHVKQILEKVEKSDHYLMDRDLFQIIVTFTKAGYPQYVSEILEKITYER
RYLPDAMNLILLLVTEKLEDTAFQILLALPVSKE-------ENINVFGSFFLRHCVTVNT
PAEKLVDYCKKLKEAKLHSSSLQFTLHCALLANKTALAKAVMQALKEEGF-PIRTHYFWP
LLAGHQKTKNVQGIMDILKIMKELGVDPDQDTYVNYVFPCFGDVKSVRAALQENECLPQS
N--IFTQAAVRSEAKNGN----LENVLSLLESNAL-PLSFN-SLRGSLILGFR----RS-
------KNIDL-WSKITELLYKNGRYCQDPPGPT-EAVGYFLYHLIDSMSDSEVQAKEEH
LRQYFHQLKEMGVKVPENIYKGIRNLLDNYHVPELIKDVKVLIDNEKVDSR----KSHQL
ASSDLESTLEKLKAENQPVGDVLKQLILVLCAEENMQKALEVKAKYESD-MVIGGYAALI
NLCCRHDNAEDALTL-------------KQEFDRLDPSAVLDTAKYIG

PF01535 // ENSGT00390000016775_0_Domain_12 (889, 914)

LVKVLGKHGKLH
DAINILKEMKEKD

ENSGT00390000016775_0_Linker_12_13 (914, 1099)

VLIKDTTVTSFFHILNGAALRGEIETVKRLHEAIVTLGLAKPSTNIS
VPLVTVHLEK-DDLPAALEASIDC---HEKYKILPRIHDVLCKLI-EKGETDLIQKAMDF
VSQEQGEMTMLYDLFFAFLQTGN-HKEAKKIIETPGMRARPARLQWFCDRCISSNQVETL
EKLVE-LTEKLFECDRDQ

PF01535 // ENSGT00390000016775_0_Domain_13 (1099, 1128)

MYYSLLKLHKINGDWQRADGVWNKMQEENIIPRERTLQLLAE
ILKTSNQEVPFD----VPELWFGDDR-PSLN---S-SSPPAVETDTEKMLLSACRLRKNK
-DAYSIFLKAQKQNIVFSSETYSTLIGLLLKKDDF-TQAMEVK-DFAETHIKGFTLNDAA
NSLLIITQVRRDYLKVALTTLKAALDLEQIPSKLAVTRLIQAFAMKGDLESIEAIQSMVN
GLD-AIGLSSMVFINNIALAQMKNNNIDVAIENIEH--MLTSEKPTIEPQYFGLSYLFRK
VLEEQMEPALEK----------------------------------------LSIMSERL
ANQFALYKPVTDLFLQLVDSGKVDEARALLERCGAIAEQSSILLVFCLRSAQKPKKA---
-PVLKTLLELIPELREKKEAYSSSMKSYALDKDVTSAKALYEHLTAKNVELDDLFLKRYA
TLLKDVGEPVPFTEPPESFEFYVKQLKEAKENPS----------

------------------------------------------------------------
---MAALLNSARRLRPLY-----------SRLLRL-------PRGAA--S-HRPSPRAAG
LAGAPGSTHLIYQARLLAV-APHQKGKVQEEPVPG-----IQNKQVRNFDWALNRLDTSV
RRTGRITKTLLLRIFHDMCR-TG--------------------------TELAHMIWSKL
QELGAVYDASHYNALLKVYLQNEHKFSPTEFLSQMEKAKVQPNR

PF01535 // ENSGT00390000016775_0_Domain_6 (285, 313)

VTYQRLIAAYCNEGDI
EGASKILGFMKVKELPITEAVFSSLVTGHARTGHLQRYGECSKYPFSDEGC---------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------

------------------------------------------------------------
---------MAALLRSARWLLRAGAAPRLPLSLRL------LPGGP-G--RLHAASYLPA
ARAGPVAGGLLSPARLYAI-AAKEKDI-QEES------TFSSRKISNQFDWALMRLDLSV
RRTGRIPKKLLQKVFNDTCRS-GGLGGSHALLLLRSCGSLLPELKVEERTEFAH

PF13812 // ENSGT00390000016775_0_Domain_5 (235, 294)

RIWDTL
QKLGAVYDVSHYNALLKVYLQNEYKFSPTDFLAKMEEANIQPNRVTYQRLIAS

ENSGT00390000016775_0_Linker_5_7 (294, 308)

YCNVGDI
EGASKIL

PF17177 // ENSGT00390000016775_0_Domain_7 (308, 417)

GFMKTKDLPVTEAVFSALVTGHARAGDMENAENILTV-MRDAGIEPGPDTYLA
LLNAYAEKGDIDHVKQTLEKVEKSELHLMDRDLLQIIFSFSKAGYPQYVSEILEKVTCER
RYIPDAMNLILLLVTEKLEDVALQILLACPVSKE-------DGPSVFGSFFLQHCVTMNT
PVEKLTDYCKKLKEVQMHSFPLQFTLHCALLANKTDLAKALMKAVKEEGF-PIRPHYFWP
LLVGRRKEKNVQGIIEILKGMQELGVHPDQETYTDYVIPCFDSVNSARAILQENGCLSDS
D--MFSQAGLRSEAANGN----LDFVLSFLKSNTL-PISLQ-SIRSSLLLGFR----R--
-----SMNINL-WSEITELLYKDGRYCQEPRGPT-EAVGYFLYNLIDSMSDSEVQAKEEH
LRQYFHQLEKMNVKIPENIYRGIRNLLESYHVPELIKDAHLLVESKNLDFQ----KTVQL
TSSELESTLETLKAENQPIRDVLKQLILVLCSEENMQKALELKAKYESD-MVTGG

PF01535 // ENSGT00390000016775_0_Domain_11 (836, 873)

YAALI
NLCCRHDKVEDALNL-------------KEEL

ENSGT00390000016775_0_Linker_11_12 (873, 888)

DRLDSSAVLDTGKYV

PF01535 // ENSGT00390000016775_0_Domain_12 (888, 914)

GLVRVLAKHGKLQ
DAINILKEMKEKDVLIKDTTALSFFHMLNGAALRGEIETVKQLHEAIVTLGLAEPSTNIS
FPLVTVHLEK-GDLSTALEVAIDC---YEKYKVLPRIHDVLCKLV-ENGETDLIQKAMDF
VSQEQGEMVMLYDLFFAFLQTGN-YKEAKKIIETPGIRARSARLQWFCDRCVANNQVETL
EKLVE-LTQKLFECDRDQMYYNLLKLYKINGDWQRADAVWNKIQEENVIPREKTLRLLAE
ILREGNQEVPFD----VPELWYEDEK-HSLNS----SSASTTEPDFQKDILIACRLNQKK
-GAYDIFLNAKEQNIVFNAETYSNLVKLLMSEDYF-TQAMEVK-AFAETHIKGFTLNDAA
NSRLIITQVRRDYLKEAVTTLKTVLDQQQTPSRLAVTRVVQALAMKGDVENIEVVQKMLN
GLEDSIGLSKMVFINNIALAQIKNNNIDAAIENIEN--MLTSENKVIEPQYFGLAYLFRK
VIEEQLEPAVEK----------------------------------------ISIMAERL
ANQFAIYKPVTDFFLQLVDAGKVDDARALLQRCGAIAEQTPILLLFLLRNSRKQGKA---
-STVKSVLELIPELNEKEE

PF01535 // ENSGT00390000016775_0_Domain_20 (1520, 1544)

AYNSLMKSYVSEKDVTSAKALYEHLTAKNTKLDDLFLKRYA
SLLKYAGEPVPFIEPPESFEFYAQQLRKLRENSS----------

------------------------------------------------------------
---------MAALLRPARWLLGAAATPRLPLTLRL-------LAGGPG--RLFSVSRVAA
AGGRPPARELLSQARLYAI-AAE-KRDLQEEPA-------PVRRNSSQFDWALMRLDNSV
RRTGRITKGLLQKVFESTCR-SGSPGGNQALLLLRSCGSLLPELSLAERTEFAH

PF13812 // ENSGT00390000016775_0_Domain_5 (235, 294)

KIWDKL
EKLGVVYDVSHYNALLKVYLQNEHKFSPTDFLAKMERANIQPNRVTYQRLIAA

ENSGT00390000016775_0_Linker_5_7 (294, 309)

YCDVGDI
EGASKILG

PF17177 // ENSGT00390000016775_0_Domain_7 (309, 417)

FMKTKDLPVTEAVFSALVTGHARAGDMENAENILTV-MKEAGIEPGPDTYVA
LLSAYAEKGDIDHVKQTLEKVEKSDHYLTGRDLLQVIVTLSKAGYPQYVSQILEKVTFER
RYIPDAMNLILLLVTEKLEDTAFQILLALPMSKE-------ESINASGSFFLRHCVTMDT
PAEKLIDYCKKLKEAKLHSFSLQFILQCALLANKTALAKAVMQALKEEDF-PIRPHYFWP
LLVGHQKTKNVEGIIDILKIMNELEVDPDQDTYINYVFPCFDNVESAQAALQKNECLPKG
N--KFAQAELRSEAMNGN----LQNILSLLESNEF-PLSLN-SLRSSLILGFR----RS-
------MDVDL-WSKITELFYKDGRYSREPSAPT-EAVGYFLYQLIDSMSDSEVQAKEEH
LRQYFHQLKKMNVKVPENIYKGIRNLLDSYHVPELIKDVKVLVDREKVDSW----KTSQL
TPSDLESQLERLQADNQPIGDVLKQLVLLLCSEENMQKALEVKAKYESD-MVIGG

PF01535 // ENSGT00390000016775_0_Domain_11 (836, 871)

YAALI
NLCCRHDNVEDALNL-------------KQ

ENSGT00390000016775_0_Linker_11_12 (871, 888)

EVDRLDPSAVLDTAKYV

PF01535 // ENSGT00390000016775_0_Domain_12 (888, 914)

GLVKVLGKHGKLQ
DAIKILKEMKEKDVVIKDSTVMSFFHILNGAALRGEIETVKQLHEAIVTLGLAKPSTSIS
IPLVTVHLEK-DDLPAALEASIDC---CEKYKILPRIHDVLCKLI-EKGETDLIQKAMDF
VSHEQGEMSMLYDLFFAFLQTGN-YKEAKKIIETPGIRARPARLQWFCDRCIFSNRVETL
EKLVE-LTQKLFECDRDQMYYSLLKLHKINSDWQRADAVWNKMQEENIIPRERTLQLLAE
ILRTGNQEVPFD----VPELWFEDDS-SSLS---S-SSPPAVETITEKMLLESCNLRKNK
-DAYNIFLKAQKQNIVFNSETYSTLISLLLRRDCF-TQAMQVR-DFAETHIKGFTLNDAA
NSLLIIAQVRRDYLKVAVETLKASLALEQVPSKVAITRLIQACALKGDLESIEAIRGMVN
GLD-EIGLSKMVFINNTALAQMKNNNIDVAIENIEH--MLTSENRTIEPQYFGLSYLFRK
VIEEQMQTALER----------------------------------------LSIMSEKL
ANQFALYKPVTDLFLQLLDSGKVDEARALLERCGAIAEQSSVMAVFCVRSSQKRNKA---
-PVLKTLLELIPELYDKKEAYSSIMKSYVLDKDVASAKELYEHLTAKNMPLDELFLKRYA
TLLKEVGEPVPFTEPPASFEFYVKQLKEAKENPS----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------MNLCLSLITEKLEDTAFQVLLTCPRLMAEGS---NGGAVDFGNFFLRHCVATDT
PFLKLQGFCSHLRDAHLHAAPFQFSLHCALSSGKTVLAFELMKALKEGGYHPVRTHYFWP
LLARCQKEKNVAGVFRILRGMQEMGVQPDVDTFANYVIPCFENVQTARAQLQENGCLPES
D--TFSGAEFRIEAMSLFTASDEELSSLVVSSQSS-PLDVS-ALRNNLVQGFK----RK-
------WGIFN-LAPIKSHMSGDASGGRDG-SSSAEAVGYFLYNLIDSMSDSEVQAKEER
LRQYFHQLKKMNMVIPENLFKGIRNLLDAHHVPELIKDVALLIDREQLDLR----KRMPF
KSASLEEELESLKAEKQPIGDVLKRLILALCAEEDMEKALDVKAKYEAD-MAVGGYAALI
NLCCRHDNAAGALSL-------------KQDVDRMDPTVVLDTSK

PF01535 // ENSGT00390000016775_0_Domain_12 (886, 914)

YVALVKVLAKHSQLQ
DAINILKEMKEKDVLIKDTTVTSFFHILNGAALRGDAETVKELHEAILQLGLAKPTTSLC
SPLVTVHLEK-NDPQAALEASMDC---YKKYHKIPRIHDVLCQLI-EKGEADLIQKAMEF
VSQEQGEMSMLYDLFFAFLQTGK-YKEARKVIETPGIRARPGRIQWFCERCIINNQVETL
EKLVE-LTKNLFECDRDQMYYYMLKLCKENGDWQRADAAWNKLQEENIIPREKTLRLLAE
ILRDSNQEVPFT----VPELWHEDVN-VPKAPALVESTLSPLEKDFRKRILNSCQKNGSP
-EAYNIFLEAQKKNIVFDASTYSSLLRALLSDGCL-EEFTKVRSV---------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------

------------------------------------------------------------
---------MAALLRPARWLLRAGPAPRLPLALRL-------LVGGPG--RPHGAPRLPA
PRA-SVTGELVSQARQYAI-AAEKKNYLQEDSM------AAHQRNASQFDWALMRLDNSV
RRTGRIPKTLLQKVFDNTCN-SGSPGGNQALLLLRSCGSLLPELKVSERTELVHRIWDKL
QKLGTVYDVSHYNALLKVYLQNEYKFSPTDFLAKMEEANIQPNR

PF01535 // ENSGT00390000016775_0_Domain_6 (285, 319)

VTYQRLIAAYCNVGDI
EGASKILGFMKSKDLPVT

ENSGT00390000016775_0_Linker_6_8 (319, 320)

E

PF01535 // ENSGT00390000016775_0_Domain_8 (320, 355)

AVFSALVTGHARARDMENAENILTV-MKEAGIEPG

ENSGT00390000016775_0_Linker_8_7 (355, 356)

P

PF01535 // ENSGT00390000016775_0_Domain_7 (356, 390)

DTYLA
LLNAYAEKGDIDHVKQTLEKVAKSDLYLMDRDLLQIIFSFSKAGYPQYVTEILDKITYER
RYLPDAMNLILRLITENLEDTALQILLACPVSRE-------DGLGDFGSFFLRHCVAVNT
PVEKLKDYCKKLEESQMHSSPFQFTLHCALVAKKADLAKALMKSLKGEGF-PIRT

PF01535 // ENSGT00390000016775_0_Domain_10 (536, 570)

HYFWP
LIVGHQKEKSVQGIIEVLKGMQEMGVNPD

ENSGT00390000016775_0_Linker_10_11 (570, 834)

QETYINYVFPSFDSIKSARAILQENGCLPDD
N--TFSQAELRSEALNGN----LNFVLS-LESDSL-PFSFS-SFRASLILGFK----RN-
------MDVNL-WSKITELLYKDGRYCQEPLGAR-EAVGYFLYNLIDSMSDSEVQAKEEH
LRQYFHQLKEMNLKIPENIYRGIRNLMDSYHVPELIKDVNLLVDREKTDSS----KTSRF
TASDLEATLERLKAENQPVRDVLKQLILTLSSEENMQKALEVKAKYESD-MVI

PF01535 // ENSGT00390000016775_0_Domain_11 (834, 881)

GGYAALI
GVCCRHDSVEDALTL-------------KQEFDRLDPSAV

ENSGT00390000016775_0_Linker_11_12 (881, 884)

LDT

PF01535 // ENSGT00390000016775_0_Domain_12 (884, 918)

RKYVNLVKVLGKHGKLQ
DAMNILKEMKEKDVLIK

ENSGT00390000016775_0_Linker_12_13 (918, 1098)

DATVLSFFHVLNGAALRGEVETVQQLHEAIVTLGLASPSTSIS
SPLVTLYLEK-DDLPAALQASIDC---YKKYKVLPRIHDVLCGLI-EKGETDLIQKAMDF
VSQEQGEMTMLYDLFFAFLQTRN-YKEAKKIIETPGMRARPTRLQWFSERCITSNQVETL
ENLVE-LTQKLFECDRD

PF01535 // ENSGT00390000016775_0_Domain_13 (1098, 1132)

QLYYNLLKLYKMNGDWQKADAVWNKMQEENIIPREKTLRLLAE
ILRNNNQEVPFD----VPELWYEDEK-HPLT---S-SPPVPVEMKLRKDLLIACQRNQSK
GTAFNIFLRAQDQNIVFNSETYSNLIKLLLLKDSF-TQAMQVK-TIAETHIKGFTLNDAA
NSLLLITQVRRDYLKEALETLKAALDLEQLPSRMAVTRLVQACALKGDVESIHAIEKMVS
GLENSIGLSNM-FINNTXXXXXXXGHTDVAVESLES--MLTSGSPSVEPQFFGLAYLFRK
VIEERLESALEK----------------------------------------LSIMAERL
ANQFAVYKPVTDLFLQLVDSGKVDDARALLQRCGAIAEQTPILSIFCIRSAQRPGKT---
-PTMKSLLELILKLIEKE

PF01535 // ENSGT00390000016775_0_Domain_20 (1519, 1553)

EIYASIMKIYALDNDVASAKAMYGHLTAKNIKLNDLFLKRYA
VLLRTVGEDVPFPEPPETFEFYVKQLKESKEASL----------

------------------------------------------------------------
---------MASLLRSSFWLLRAGAAPRLPLSLRL------LTGG-PG--RPHAASYLPA
ARAGPVAGGLLSPARLYVI-AAEKKDI-QEES------TFSSRRIANHFDWALMRLDNSV
RRTGHIPKMLLQKVFDDTCRS-GGPGSSHALLLLRSCGSLLPELKLEERTEFAHRIWDKL
QKLGAVYDVSHYNALLKVYLQNEYKFSPTDFLAKMEEANIQPNR

PF01535 // ENSGT00390000016775_0_Domain_6 (285, 314)

VTYQRLIASYCNMGDI
EGASKILGFMKTK

ENSGT00390000016775_0_Linker_6_8 (314, 321)

DLPVTEA

PF01535 // ENSGT00390000016775_0_Domain_8 (321, 351)

VFSALVTGHARAGDMENAENILTV-MREAG

ENSGT00390000016775_0_Linker_8_7 (351, 357)

IEPGPD

PF01535 // ENSGT00390000016775_0_Domain_7 (357, 384)

TYLA
LLNAYAEKGDIDHVKQTLEKVEKSELHLMDRDLFQIIFSFSKAGYPQYVSEILEKVTCER
RYIPDAMNLILLLVTEKLEDIALQILLACPISKE-------DGISDFGSFFLRHCVTMNT
PVEKLTDYCKKLKEIQMHSFPLQFTLHCALLAQKTDLAKALMKAVKEEGF-PIRTHYFWP
LLVGHQKEKNVQGIIEVLKVMQELGVHPDQETYANYVIPCFDSIKSARAILQENGCLSNS
D--MFSQAELRSEAVNGN----LDFVYSFLESNTS-PLSLQ-SIRSILLLGFR----RS-
------MNINL-WSKITELLYKDGRYCQEPPGPT-EAVGYFLYNLIDSMSDSEVQAKEER
LRQYFHQLKEMNVKIPENIYRGIRNLLDSYHVPELIKDAYMLVDSEDLDSR----KTVQL
RSSELESRLETLTAENQPIRDVLKQLILALCSQENMQKALELKAKYESD-MVISG

PF01535 // ENSGT00390000016775_0_Domain_11 (836, 871)

YAALI
NLCCRHDNAEDALNL-------------KE

ENSGT00390000016775_0_Linker_11_12 (871, 888)

EFDRLDSSAVLDTSKYV

PF01535 // ENSGT00390000016775_0_Domain_12 (888, 914)

GLVRVLAKHGRLQ
DAINILKEMKKKD

ENSGT00390000016775_0_Linker_12_13 (914, 1099)

VPIKDSTVLSFFHILNGAALRGEIETVKQLHEAIVTLGLAKPSTNIS
FPLVTVYLEK-DDLSTALDVAIDC---CEKYKILPRMHDILCKLI-EKGETDLIQKAMDF
VSQEQGEMMMLYDLFFAFLQTGN-YKEAKKIIETPGIRARSTRLQWFCDKCIANNQVETL
EKLVE-LTQKLFECDRDQ

PF01535 // ENSGT00390000016775_0_Domain_13 (1099, 1128)

MYYNLLKVYKMNGDWQRADAVWNKIQEENIIPREKTLRLLAE
ILRDGNQEVPFE----VPEKWYEDEK-HSLNSSSDSSSDSTTEPGFQKDILYACQLKQSK
-EAYGIFLKAKQQNVVFNAETYSDLIKLLLSKESF-TQAVEVK-AFAETHIKGFTLNDAA
NSLLIITQVRRDYLKEALTTLKTALDQQQTPSRVAVTRLIQALAMKGDVENIEVVQKMVN
GLEDSIGLSKMVFINNTALAQIKNNNIDVAIENIEN--MLTSENQVTEPQYFGLAYLFRK
VIEEQLEPAVEK----------------------------------------ISIMAERL
ANQFAIYKPVTDFFLQLVDAGKVDDARALLQRCGAIAEQTPILLVFFIRNSGKQGKA---
-STLKSLLELIPELNEKEEAYSSLMKCYVSEKDVTSAKALYEHLTAKNTKLNDLFLKRYA
FLLKNAGESVPFTEPPESFEFYVQQLKELRENSS----------

------------------------------------------------------------
---MSALLAG------ARFLLRPGLRALPAPCVRL-------SPGQGSAANYMAIISVCG
AGGSGGGRYLNNTPGHFAI-AAQQKGHIHEEPVSA-----VRAKQAQQFDWALNKLDSSV
RRTGRITKTLLQKIFHDVCR-TGYPSSNQALLLL

PF01535 // ENSGT00390000016775_0_Domain_4 (215, 249)

RSCGSLLPELQMSERTEMAHRIWEKL
QELGAVFDVSHYNALLKVYLQNEHKFSPTEYLAKMEAANVQPNR

PF01535 // ENSGT00390000016775_0_Domain_6 (285, 319)

VTYQRLIAAYCNEGDI
EGASKILGFMKNKDLPIT

ENSGT00390000016775_0_Linker_6_8 (319, 320)

E

PF01535 // ENSGT00390000016775_0_Domain_8 (320, 355)

AVFNTLVTGHARAGDMENAKNILSV-MRSAGIEPG

ENSGT00390000016775_0_Linker_8_7 (355, 356)

P

PF01535 // ENSGT00390000016775_0_Domain_7 (356, 390)

ETYVA
LLTAYAEKGDINNIKQTLENVEKNEGSLTDRDLMQVIWSLAKAGYPQYVQDIVERMRYDR
GYIPDAMNLCLSLMTQGFEDVAFLVLKSFSAASHDSP---NGDSLHHGNFFLRHCVNLDK
PANKVKQFCDGLKEENLHSAPLQFALYCSLDAKKADLALELMKMMKQEGM-PVRPHYCWP
LLISFQKEKNAEGTIKVIKALSEIGVELDVETYSNYVLSVFNDVKSARAQLQEHGCTVDS
S--WFNLAELRHDAVSGN----LEEVYSLLSSPSFPSVDLG-HFRGSLITAFK----RS-
------NNVDL-KAKITELLYKDGRYCQAASGPN-EAVGYFLYNLIDSMSDAEVQAKEEH
LRQYFHQLKNANIVISANIYRGIRNLLDSSHVPELIKDVIVLVDSQETLTSSDIAKSAEL
KASTLEEEIETLKAENKPFGDVLKQLVMIHCSEENMQKALEVKAKYEQENLAI

PF01535 // ENSGT00390000016775_0_Domain_11 (834, 881)

GTYAALI
QLCCRHDNPDEALNL-------------KQELNRKDSSAV

ENSGT00390000016775_0_Linker_11_12 (881, 884)

LDT

PF01535 // ENSGT00390000016775_0_Domain_12 (884, 918)

SKYLALVKVFGKNGRIA
DAINVLKEMKEKDVPLK

ENSGT00390000016775_0_Linker_12_13 (918, 1098)

ETTTTSFFHILNAAALRGDAETVDKIHESIVTLGLAKPTSNLC
SPLVSVHLEK-GDLPAAMETLFTC---SKKYNCMPRLHDVLCRLV-EKGDTDLLQKAMDH
ISQERGEMAMLYDLLFAFLHTGK-YKEARKIIETPGLRARPGRLQWFAEKCIATNQMEAL
ENLVD-MTQKLFECDRD

PF01535 // ENSGT00390000016775_0_Domain_13 (1098, 1132)

DMYYYLLKLCKENDDWKKADSAWTKIQEENVIPRERTLRLLAD
IFRRNGQEVPFD----VPETWYKDAAESKVL--ASSSAPSSPESSFQKRVQILSKKNRAK
-DAYEAFMEGENNGTAMSA

PF01535 // ENSGT00390000016775_0_Domain_17 (1220, 1256)

SAYSSLIRSMLSEGML-EEAKKVL-NTAENHIKGFTLNDAA
SSLLIITQVRRDYLKDALASLKAMLEGDKVPTQLAVTRLVQALALKGDLEGIEVVENMMR
NIGSSIRLSQMLFINNKMLAHLKRGKTEEAIELIEP--LYTG----TDSQVTSISYVFRK
AMEEKMESALEK----------------------------------------LSGMAERL
ANQFAVYRPVTDLFLQYIQVGRKDDARFLLQRCGSIAEQTPVLVSFISRSAQIPGQA---
-QLIKDLLELIPEFSERE

PF01535 // ENSGT00390000016775_0_Domain_20 (1519, 1553)

TAYSYLMKCYATDKDATAATALYEKMKSESVSPDELFLKRLA
VLLREAGEPVPFSEPPESFKFYADKLKKDKADSYDDEH------

MSITLTPLFSEKCGFPSSNLKRSLASPTFGAPCSWSLPRRATLR-----SRAPPVLLAER
ASRCGDVRAMAALLRFSCWLLRAGEAPRLPLSLRL------LTGG-PG--RPHAASYLPA
ARAGPVAGGLLSPARLYVI-AAEKKDI-QEES------TFSSRRIANHFDWALMRLDNSV
RRTGRIPKMLLQKVFDDTCRS-GGPGSSHALLLLRSCGSLLPELKLEERTEFAH

PF13812 // ENSGT00390000016775_0_Domain_5 (235, 296)

RIWDKL
QKLGAVYDVSHYNALLKVYLQNEYKFSPTDFLAKMEEANIQPNRVTYQRLIASYC

ENSGT00390000016775_0_Linker_5_7 (296, 309)

NMGDI
EGASKILG

PF17177 // ENSGT00390000016775_0_Domain_7 (309, 417)

FMKTKDLPVTEAVFSALVTGHARAGDMQNAENILTV-MREAGIEPGPDTYLA
LLNAYAEKGDIDHVKQTLEKVEKSELHLMDRDLFQIIFSFSKAGYPQYVSEILEKVTCER
RYIPDAMNLILLLVTEKLEDVALQILLACPISKE-------DGISDFGSFFLRHCVTMNT
PVEKLTDYCKKLKEIQMHSFPLQFTLHCALLAKKTDLAKALMKAVKEEGF-PIRTHYFWP
LLVGHQKEKNVQGIIEVLKVMQELGVPPDQETYIGYVIPCFNSIKSARAILQENGCLSNS
D--TFSQAELRSEAINGN----LDFVLSFLESNTL-PLSLH-SIRSSLLLGFR----RS-
------MNINL-WSKITELLYKDGRYCQEPPGPT-EAVGYFLYNLIDSMSDSEVQAKEER
LRQYFHQLKEMNVKIPENICRGIRNLLDSYHVPELIKDAYMLVDSENLDSQ----KTVQL
RSSELESRLETLKAEDKPVRDVLKHLILMLCSQENMQKALELKAKYESD-MVISG

PF01535 // ENSGT00390000016775_0_Domain_11 (836, 871)

YAALI
NLCCRHDNAEDALNL-------------KE

ENSGT00390000016775_0_Linker_11_12 (871, 888)

EFDRLDSSAVLDTSKYV

PF01535 // ENSGT00390000016775_0_Domain_12 (888, 914)

GLVRVLAKHGRLQ
DAINILKEMKKKDVPIKDSTVLSFFHILNGAALRGEIETVKQLHEAIVTLGLAKPSTNIS
FPLITVYLEK-DDPSTALDVAIDC---CEKYKILPRMHDILCKLI-EKGETDLIQKAMDF
VSQEQGEMVMLYDLFFAFLQTGN-YKEAKKIIETPGIRARSTRLQWFCDKCIANNQVEAL
EKLVE-LTQKLFECDRDQMYYNLLKLYKMNGDWQRADAVWNKIQEENIIPREKTLRLLAE
ILRDGNQEVPFE----VPE-WYEDEK-HSLNSSLDSSSDSTTEPGFQKDILNACQLKQSK
-EAYGIFLKAKQQNVVFNAETYSDLIKLLLSKEYF-TQAVEVK-AFAETHIKGFTLNDAA
NSLLIITQVRRDYLKEALTTLKTALDQQQTPSGIAVTRLIQALAMKGDVENIEVVQKMVN
GLEDSIGLSKMVFINNTALAQIKNNNIDVAIENIEN--MLTSENPVIELQYFGLAYLFRK
VIEEQLEPAVEK----------------------------------------ISIMAERL
ANQFAIYKPVTDFFLQLVDAGKVDDARALLQRCGAIAEQTSILLVFFLRNGGKQGKA---
-STLKSLLELIPELNEKEEAYSSLMKSYVSEKDVTSAKALYEHLTAKNTKLDDLFLKRYA
FLLKNAGESVPFTEPPESFEFYVQQLKELRENSS----------

------------------------------------------------------------
------------------------------------------------------------
----------MNQIRFLTL-APQEEGTVKEEPVSE-----VRTRPTWQFDWALNKVDNSV
RKTGRIPKALLLKIFQEISK-AGCPGSNQTLLLLQSCGAVLPEVLSPERTELAHMMWDKM
KELGAVYDTSHYNALLKVYLQNEHKFSPTEFLARMEEANVQPNR

PF01535 // ENSGT00390000016775_0_Domain_6 (285, 314)

VTYQRLIAAYCNEGDI
EGASKILGFMKSK

ENSGT00390000016775_0_Linker_6_8 (314, 321)

DLPITEA

PF01535 // ENSGT00390000016775_0_Domain_8 (321, 351)

VFSSLVKGHARSGDMKSAENILSV-MRMAGVEPGPDTYLS
LLNVYAEKGDADSIKKTLEQIEKTKGYLMDRILVQVIFSLAKAGYPQHIEDVKGRIKFEK
ELIPDVMNLCLTLITHGFEDISFSILKSLSHLSR--------EDLDQGSFFLQHCVNRDL
PVSKLKQFCTELKEAKMHSAPLPFVLRCALETNRLALAIDVMKLMKEEGL-PLRPHYCWP
LLVAYQKQNNLKGIFEVLKTMHKLGVDLDAETYTDYVFKNFADTETAHAQLKENGCLFES
V--GLYTAELRSEALKGR----LDKVLSILSSANTPATDSR-LFRNSLIWGFK----SS-
------DDVQL-WSKITELLYKDERYCLTPPGPT-EAVGYFLYHLIDSMSDSEVQAKEER
LRQYFHQLKKMNIVIPTSHYNGICRLLDSTQVPELIKDARLLCNK-KSLS-TDISESAKS
DVSALEKKLEQRKAENQPITDVLKQLIHALCEEENMQKALEVKAKYEPD-MVVGG

PF01535 // ENSGT00390000016775_0_Domain_11 (836, 855)

YAALI
NLCCRHDNVEEAMN

ENSGT00390000016775_0_Linker_11_12 (855, 886)

L-------------KEKVFPRNSPVALDSGK

PF01535 // ENSGT00390000016775_0_Domain_12 (886, 914)

YVALIEVLEKHGRLE
DAINILTEMKEKDVPISGRTVASFLRILNAAATRGDVETVNRLHETIANLGLVQ-TAALH
APLITVHLEK-DDMPAALEALISC---YKKYGKILQLHNIYCKLV-EKGDADLLQKVSDF
VSREYGDMMALYDLFFAFLRTGK-YKEAKKVIETPGLRAHSGRLQWFAKKCILNNQMEAL
EQLVE-LTRNLFECDRDAMYYHLLELCESSKEWGKAEAIWTKIQEENIVPREKTLILLAD
IFKKNGQVVPFE----VPK---GRP--EDSRSAASG--EELK-------

PF01535 // ENSGT00390000016775_0_Domain_15 (1190, 1213)

IQMLCKKNKAK
-EAYNIFRRMPEKDE-SHYRSCDILVKALLAQNCL-DEALDVK-RIAETHIKGFTLNSAA
SSLLIISQVRRDYLKDALAALKGMLDRGMLPTRSAVTALIQALAEKGDIKSLQVLENILG
DITKSLGISDSIIPNAIALAHTKSNDLDAAVKYLEP--LLISGVQNPDQAVKSISFLLRI
VSEEGLEPALEK----------------------------------------FGAMAERL
ASQFGIYRPVTDLFLQYISADRVDDARSLIQRWDAIAQEKRTLGRFMARSASKPGQA---
-KKIETLLELIPERLDPATAYRYLLRCYELDGDVASVKATYEKTKAKNIELHEISLKSLA
TFLKKVGEPVPFTEPPETFKFYVEKWKNRRLEAS----------

------------------------------------------------------------
------------------------------------------------------------
--------GLLSPARLYAI-AAKEKDI-QEES------TFSSRKISNQFDWALMRLDLSV
RRTGRIPKKLLQKVFNDTCRS-GGLGGSHALLLLRSCGSLLPELKLEERTEFAH

PF13812 // ENSGT00390000016775_0_Domain_5 (235, 294)

RIWDTL
QKLGAVYDVSHYNALLKVYLQNEYKFSPTDFLAKMEEANIQPNRVTYQRLIAS

ENSGT00390000016775_0_Linker_5_7 (294, 308)

YCNVGDI
EGASKIL

PF17177 // ENSGT00390000016775_0_Domain_7 (308, 417)

GFMKTKDLPVTEAVFSALVTGHARAGDMENAENILTV-MRDAGIEPGPDTYLA
LLNAYAEKGDIDHVKQTLEKVENSELHLMDRDLLQIIFSFSKAGYPQYVSEILEKVTCER
RYIPDAMNLILLLVTEKLEDVALQILLACPISKE-------DGPSVFGSFFLQHCVTMNT
PVEKLTDYCKKLKEVQMHSFPLQFTLHCALLANKTDLAKALMKAVKEEGF-PIRPHYFWP
LLVGRRKEKNVQG-----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------

------------------------------------------------------------
---------MAALLRPARWLLRAGAAPRLTLSLRL------L-AGGPG--RPHVGSYLPA
ARAKPVAGGLLRPARLYVI-AAEEKDI-REES------TFSYRRVTSQFDWALMRLDSSV
RRTGRIPKTLLQKVFDNTCSS-GGPGSNQALLLLRSCGSLLPEVKLEERTEFAH

PF13812 // ENSGT00390000016775_0_Domain_5 (235, 296)

RIWDKL
QELGAVYDVSHYNALLKVYLQNEHKFSQTDFLAKMEEANIQPNRVTYQRLIASYC

ENSGT00390000016775_0_Linker_5_7 (296, 310)

NMGDI
EGASKILGF

PF17177 // ENSGT00390000016775_0_Domain_7 (310, 416)

MKTKDLPITEAVFNSLITGHARAGDMENAENILTV-MRGAGIEPGLDTYLA
LLNAYAEKGDIDHVRQTLEKVQQSELYLMDRDLLQIIFSFAKAGYPQYVSEILGKATCER
RYIPDAMNLILLLVTEKLEDTALQILLACPVSKE-------DSLSDFGSFFLRHCVTMNT
PVEKLTDYCKKLKEVQMHSSPLQFTLSCALLANKTDLAKNLMKAMKEEGF-PIRTHYFWP
LLVGHQKEKNVQGIIEVLKGMQELGVHPNQETYINYVIPCFDSVLSARAILEENGFLSDS
D--MFSQAALRTEAVKGN----LDYVLSFLESNTS-PLSLQ-SVRGSLLLGFR----R--
-----SMNVDL-WSKITELLYKDQRYCQKPPGAT-EAVGYFLYNLIDSMSDSEVQAKEER
LRQYFHQLKEMNLKIPENTYKGIRNLLDSYHVPELIKDAHMLIDNENLGSR----KTVQF
SSSKLESTIETLKAENRPIRDVLKQLILVLCSEENMQKALEVKAKYESD-MVIAG

PF01535 // ENSGT00390000016775_0_Domain_11 (836, 873)

YAALI
NLCCRHDNAEDALNL-------------KEEL

ENSGT00390000016775_0_Linker_11_12 (873, 886)

DRLDSSAVIDTNK

PF01535 // ENSGT00390000016775_0_Domain_12 (886, 914)

YVALVKVLAKHGKLQ
DAINILKEMKEKD

ENSGT00390000016775_0_Linker_12_13 (914, 1099)

VLIKDATVMSFFHILNGAALRGETETVKRLHEAIVTLGLAKPSTNIS
VPLVTVYLEK-DDPPAALEVAIEC---YEKYKILPRIHDILCKLI-EKGETDLIQKAMDF
VSQEQGEMMMLYDLFFAFLQTGN-YKEAKKIIETPGIRARPTRLQWFCDRCIASNQVETL
EKLVE-LTQKLFECDRDQ

PF01535 // ENSGT00390000016775_0_Domain_13 (1099, 1128)

MYYSLLKLYKVNSDWQKADAVWNKMQEENIIPREKTLRLLAE
ILKDGNQEVPFD----VPELWYEDEK-LSVDSSLNSST---AHPRFQNDILKACRLKQSK
-GAYDIFFKAQRQNVVFNAETYNNLLKLLLSKEYF-TQAMEVK-NFAETHIKGFTLNDAA
NSLLIITQVRRDYLKEALTTLKTALDQQQTPFQLAVTRLIQALAMKGDVENIEAVQKMVN
GLEDSIGLSRMVFINNIALAQIKNNNIDVAIENIEN--MLTSENQVMEPQYFGLGYLFRK
VLEEQLQPAVEK----------------------------------------ISIMAERL
ANQFAIYKPVTDFFLQLVEAGKVDDARALLQRCGAIAEQTAILLVFFIRNSQKPGKA---
-SALLSVLELIPELNEKPE

PF01535 // ENSGT00390000016775_0_Domain_20 (1520, 1548)

AYNSLMKSYALEGDVTSAKALYEHLTAKNIKLNDLFLKRYA
ILLKSAGESVPFTEPPESFEFYVQQMKESKENSS----------

------------------------------------------------------------
---------MAALLRPARWLLGAG--SSLPLSLRL-------LTGGPG--RPHAAPCLPA
ARARLFAGKLLSQVRLYAI-VAEKKNDLQEEPT------SSSRRNANQFDWALMRLDNSV
RRTGRIPKGLLQKVFDSTCR-SGSPGGNQALLLLRSCGSLLPELNLAERTEFAH

PF13812 // ENSGT00390000016775_0_Domain_5 (235, 295)

RIWDKL
QTLGTVYDVSHYNALLKVYLQNEYKFSPTDFLAKMEEANIQPNRVTYQRLIAAY

ENSGT00390000016775_0_Linker_5_7 (295, 307)

CNVGDI
EGASKI

PF17177 // ENSGT00390000016775_0_Domain_7 (307, 418)

LGFMKTKDLPVTEAVFSALVTGHARAGDMENAENILTV-MKDAGIEPGPDTFLA
LLNAYAEKGDIDHVKQTLEKVDKSEVYLMDRDLLQIILSFSKAGYPQYVSEILEKITYER
RYIPDAMNIILLLVTEKLEDTAFQILLACPISRE-------DSPNDFGSFFLRHCVTMDT
PAEKLTNYCKKLKEARMHMSPLQFTLHCALLANKTDLVKALMKAMKEEGF-PVRAHYFWP
LLAGHQKKKNVQGIIDVLKGMHEMGINPDQETYVNYVFPAFDSIKSVRAVLQKNECLPES
N--TFSQAELKSEAVNGN----LDYILSFLESNTE-PFSFN-SLRGSLILGFR----RS-
------MNIDL-WSKITELLYKDGRYCQEPPGPT-EAVGYFLYNLIDSMSDSEVQAKEER
LRQYFHQLKEMNIKIPESIYRGIRNLLDSYHVPELIKDVNMMVERKKIDSR----KSQQL
TPSDLESTLENLKAKNQPIGDVLKQLILMLCSEENMQKALELKAKYESD-MAVGG

PF01535 // ENSGT00390000016775_0_Domain_11 (836, 871)

YAALI
NLCCRHDNAEDALNL-------------KQ

ENSGT00390000016775_0_Linker_11_12 (871, 888)

EFDRLDPSAVLDTNKYV

PF01535 // ENSGT00390000016775_0_Domain_12 (888, 914)

GLVKVLGKHGKLQ
DAINILKEMKEKDVLIKDATVLSFFHILNGAALRGEIETVKQLHEAIVTLGLAKPSTNIS
FPLVTVHLEK-DDLYAALQATIDC---YEKYKILPRIHDVLCKLI-EKGETDLIQKAMDF
VSQEQGEMTMLYDLFFAFLQTGN-YKEAKKIIETPGIRARPTRLQWFCDRCITSNQVEAL
EKLVE-LTQKLFECDRDQMYFNLLKLYKANGDWQRADAAWNKMQEENVIPREKTLRLLAE
ILKNSNQEVPFD----VPEMWYEDDK-HSLT---ISSSPSPVETNLEKDLLNTCRMKRNR
-DAYNIFLKAQRQNIVFSSETYNKLIQLLLSKDSF-PQAMQVK-DFAETHIKGFALNDAA
NSLLIITQVRRDYLKAALTTLKTALDLKQIPSRLSVTRLIQAFALKGDIQSIEAIQKMVN
GLD-SIGLSNMVFINNIALAQIKNNNIDVAIENIEN--MLTSGNQTIEPQYFGLAYLFRK
VIEEQIEPAVEKCKLFVFVNEYRSTFSPVKLDQISLDESYPCFNKIFLTCFPVSIMAERL
ANQFAVYKPVTDLFLQLMGSGKVDDARALLQRCGAIAEQTSILSLFCIRSSQKPGTA---
-PVLTSLLELIPELCEKEEAYSSTMKSYVLDKDVASAKALYERLTAKNIKLNDLFLKRYA
VLLKHAGEPVPFTEPPESFEFYIKQLKESKETPS----------

------------------------------------------------------------
---MAGLLRTAARLRLSLWALRAGHN---AASLAF-------SPASGLSS-----AAATA
SSTSRAGRHLIYQARLFTI-ATQEKGDVQEQPVAA-----IRMKQAQHFDWALNKLDNSV
RRTGRITKTLLLKIFHDVCR-TGYPSSNQALLLLRSCGSLLPELCPTERTELGHTMWNRL
KELGVVYDVSHYNALLKVYLQNEHNFSPTEFLTKMEEANVQPNR

PF01535 // ENSGT00390000016775_0_Domain_6 (285, 313)

VTYQRLIAAYCNKGDI
EGASKILGFMKS

ENSGT00390000016775_0_Linker_6_8 (313, 321)

KELPITES

PF01535 // ENSGT00390000016775_0_Domain_8 (321, 351)

VFSALVTGHARAGDMDNAENILSV-MRDAGIEPGPDTYVA
LVKAYAEKGDLSKIEETLGNIAKTDSYLLDRDLMDIIFTLAKAGHSQYVPNILDKMRYDR
GYIPDAMNLCLTLITQGLEDTAFQVLKSFPSSSFDSQ---NEYGLDRGNFFLRHCVNTDK
PANKLEYFCDELKKANMHTSPLQLTLLCALESKKAALAFDLMKIMKKEGL-PVKSHYFWP
LLVECQKEKNVEGTIEVLKAMHELQVQPDVETYASYVLSNFDDVSSARHLLQERNCPLEI
D--AFSAAEIRHEAANER----LDKVFSLLSSENMPSLDHI-QFRGSLILGFR----RS-
------NDVDL-WSKITELLYKDGRYCQTPPGPT-EAVGYFLYSLIDSMSDSEVQAKEER
LRQYFHQLKKMNIVISPQIFRGIRNLLDNYHVPELIKDVILLMNR-ETLSQGTAAKFAGL
AASDLEEKLEQLKTENQPVQNVLKQLIFVLCSEENLQKALEVKAKYEED-MVVGG

PF01535 // ENSGT00390000016775_0_Domain_11 (836, 872)

YAALI
NLCCRHDNAEEAMNL-------------KEE

ENSGT00390000016775_0_Linker_11_12 (872, 886)

LYRKDSSTALDARK

PF01535 // ENSGT00390000016775_0_Domain_12 (886, 914)

YLALVKVLGKYGRIE
DAINVLKEMKEKDVPIKDGSATSLFHVLNSAALRGEVETVNRLFESIVALGLSKPTGNLC
SPLITAHLEK-DDLAAALEAVFDC---CKKYDKLPRLHDILCKLI-EKGNTELLQKAMDF
LNQERGEMTMLYDLFFAFLSTGK-YKEARKIIETPGLRARPSRLEWFAEKCIANNQVESL
ETMVE-LTQKLFECDRDEMYYYLLKSCKESNDWQKADAIWTKMQEENIIPRERTLRLLAD
ILKTNNQEAPFD----VPETWYDEDVESTQS--SVSLVPDQP-LNLQKKLLILCKRGNPE
-EAYNILLDAEKKDIVFQGLGYSNLIRALLSKGHL-EKAISVK-NIAETHIKGFVLNDAA
SSLLIITQVRRDYLKDAMFTLKTLLENDKVPSPLAVTRLVQALAKKGDLESIGTVEKMME
NLSSAIKLSRMLFINNTVLAHIKNNNLDGALEYIEP--MFTSGALQADSSNSSISFVFRR
LIEDKLEPALEK----------------------------------------LSAMSERL
ANQFGIYRPVTDLFLQYINARRIEDARLLLERCGAIGEQKKTLMAFLAQTAEKPGQV---
-DKIKVLLDLVPDFTDTRIVSSYLMKCYALDEDVTSAKVLYEKMKAEELHPDELFLKRLA
VLLKKNGEPVPFTEPPESFRFYAQKLKNERNDSSDED-------

------------------------------------------------------------
---------MAALLRSARWLLRAGAAPRLPLSVRL------LSGGP-G--RPHAASYLPA
PCARPVAGGLLSPARLYAI-AAKEKDI-QEES------TFSSRRISSQFDWALMRLDHSV
RRTGCIPKKLLQKVFDDTCRS-GGPGGSHALLLLRSCGSLLPELKLEERTEFAH

PF13812 // ENSGT00390000016775_0_Domain_5 (235, 294)

RIWDTL
QKLGAVYDVSHYNALLKVYLQNEYKFSPTDFLAKMEEANIQPNRVTYQRLIAS

ENSGT00390000016775_0_Linker_5_7 (294, 308)

YCNVGDI
EGASKIL

PF17177 // ENSGT00390000016775_0_Domain_7 (308, 417)

GFMKTKDLPVTEAVFSALVTGHARAGDMENAENILTV-MRDAGIEPGPDTYLA
LLNAYAEKGDIDHVRQTLEKVEKSELHLMDRDLLQIIFSFSKAGYPQYVSEILEKVTCER
RYIPDAMNLILLLVTEKLEDVALQILLACPVSKE-------DGSIVFGNFFLRHCVTMNT
PVEKLTDYCKKLKEVQMHSFPLQFTLHCALLANKTDLAKALMKAMKEEGF-PIRTHYFWP
LLVGHRKEKNVQGIIEILKGMQELGVHPDQETYVDYVIPCFDSVNSARAILQENGCLSDS
D--TFSQAELRSEAANGN----LDFILSFLKSNTL-PVSLQ-SVRSSLLLGFR----R--
-----SMNINL-WSEITELLYKDGRYCQEPPGPT-EAVGYFLYNLIDSMSDSEVQAKEEH
LRQYFHQLKKMNVKIPENIYRGIRNLLGSYHVPELIKDAHLLVDSKNLDFQ----KTVQL
TSSELESTLETLKAENQPIRDVLKQLILVLCSEENMQKALELKAKYESD-MVTGG

PF01535 // ENSGT00390000016775_0_Domain_11 (836, 871)

YAALI
NLCCRHDNVEDALNL-------------KE

ENSGT00390000016775_0_Linker_11_12 (871, 888)

EFDRLDSSAVLDTGKYV

PF01535 // ENSGT00390000016775_0_Domain_12 (888, 914)

GLVRVLAKHGKLQ
DAINILKEMKEKDVLIKDTTALSFFHILNGAALRGEIETVKHLHEAIVTLGLAEPSTNIS
FPLVTVYLEK-GDLSTALEVIIDC---YEKYKVLPRIHDVLCKLV-EKGETDLIQKAMDF
VGQVQGEMMMLYDLFFAFLQTGN-YKEAKKIIETPGIRARSARLQWFCDRCVANNRVETL
EKLVE-LTQKLFECDRDQMYYNLLKLYKINGDWQRADAVWNKIQEENVIPRAKTLRLLAE
ILRESNQEVPFD----VPELWYEDEK-HSLNS----SSASTTEPGFQKDILNACRWKQKE
-GAYGIFLKAKEQNVVFNAETYSDLIKLLMSEDYF-TQAMEVK-AFAETHIKGFTLNDAA
NSRLIITQVRRDYLKEAVTTLKTVLDQQQTPSRLAVTRVIQALAMKGDVENIEVVQKMLN
GLEDSIGLSKMVFINNIALAQIKNNNIDVAIENIEN--MLTSENQVIEPQYFGLGYLFRK
VIEEQLEPAVEK----------------------------------------ISIMAERL
ANQFAIYKPVTDFFLQLVDAGKVDDARALLQVMTLH---------------SWSSGA---
-STVKSMLELIPELNEKEE

PF01535 // ENSGT00390000016775_0_Domain_20 (1520, 1545)

AYNSLMKSYVSEKDVTSAKALYERLTAKNTKLDDLFLKRYA
SLLKNAGEPVPFIEPPESFEFYAQKLRKLRENSS----------