Query Results 

----------MAASGLDHLKN-----------GYRRRFCRPSRARDINTQQGQNVLKILQ
DCFEEQSLANDFSTNSTKSVLYSTHKIKDTCIQ-SRSK-----ECQKSHPKS----VPVS
SRKKE-A-----------SLQFVVEPSEATNRSVQAHEVRQKILAT-DVSSKNTSDPKKM
SS--RNINDYHSDAGEEFYLSVGSPSVLLDAKTSVS--Q------------NVIPSSAQK
RETYTFENSVNTLPSSTEVSLKTKKRLNFEDKVMLKKIEIDNKVSDEEYKTSEG-QERKP
S---GSSQNITRDSEYEIQRKAKKSFSTLFLETVKRKSKS--SPIVRHAATAPPHSCP--
--PDDKKVIEDEFIIDESDQSFASRSWITIPRKAGPLKQ-RPISP-AESTALL-QNRK-S
-----------------------REKHHNILPKTLANGKHSHE-----------------
-------------------PHPVEPSQSSDKTVLDTSCALTGETENDCKSAKYEMCSKDA
EKSSGS--KRTIKQKQRR-KFKAKPAEEQLDVGQSKDENIRMSHT-TQDKFQR--NSDRN
IEE---REEIGDDC----VSNKQMS-PVGSKK--SSA------KKDKGEAK-KK------
-HFSNES--------------------KN-KLV--PEEV-ISTVTRSRRISRHPSDWWVV
KSEESPVYSNS-SIRNELPVHRNSSQKS-AKKTNQSSKNIGEKTIPLKRQKIATKGNQRV
Q-K---FLHAKGSGG---TV-GHD-EISSCSLS---EPL---------ESDEEDLAKKKN
LYCSRS--TRSSKKE--------------DNVM-TAQ-HVPLKPQTS-GYTYNT-PTESS
-------------------LDSGERKTLVLEESGPSRLSNNYLTSGKKNNDVDEEEVHGS
S--------------DDS--KRSKVIP---KNRIHHKLVLPSNTPNVRRTKRTRLKPLEY
WRGERIDYQGRPSGGFVIGGILSPDTMSSKR-KAKENIGKVDKKSNKK-RICLDNDERKT
-SLMVNLGIPLGDPLQPTRVKDPETREIIL-MDLVRPQDTYQFFVK-----HGELKVYKT
LDTPFFSTGKLILG

PF07883 // ENSGT00390000016737_Domain_2 (1155, 1216)

PQEEKGKQHVGQDILVFYVNFGDLLCTLHETPYIISTGDSFYVPSG
NYYNIKNLLNEESVLLFTQIKR------------------------

----------------

PF15622 // ENSGT00390000016737_Domain_0 (17, 193)

DYLKN-----------DYRRRFCRPSRVPEIHAKQGQDMLEILQ
DCFEEKSKALLLDSFGGYNE-------SNYTFV-SQK---KNEYSETPHPKS----IPVS
SRKKE-A-----------SLQGIVEPTEAVSR----------------------------
------------

ENSGT00390000016737_Linker_0_1 (193, 368)

PANEEFYISVGSPVVLLDGKTSTV--Q------------SAIPSANQK
KETYNFRNSANRPSSSTEISLKTKKRLTFEGKDM-KNVEVENKVPEATDKISEGQQERNS
A---ETPQTERQDLKNEIQPQAKKSFSTLFLETVRKKSES--SPIVRHPVTTPPPSSP--
---SDKT

PF15620 // ENSGT00390000016737_Domain_1 (368, 739)

LLEDEFVIDDSDKSLASPSWITIPRKGAPLKH-HTISP-NENSSLI-QDNK-S
-----------------------RGKQKSILPKTLTSDRHSRK-----------------
-------------------APSVEKSQPSGEKILGTSYTLIDELEDNHASMRYKMCSKNV
EKHPSS--KKTIKQKERR-SLKASVVEEQCDMGQCEDENRNMSHI-AQDKLKR--NSGRN
TED---CEETKNDH----ISEKQTL-PVGNKKKKGCT------KKDKEVTE-KK------
-VNSKGS--------------------KN-KFV--PEEV-TFNITRSRRLSRRPSNWWVV
KSEESPIHGNS-PVRNEL

ENSGT00390000016737_Linker_1_2 (739, 1136)

SLNYSSRQKP-AK-KNQSSKNVGKKPVSSKKQKKSTQGTSKV
Q-K---SLKIKDSGG-------HD-EISGSSQD---EPL---------ETDKSFCRIMNC
FKLYFHRTTGYSKDQ--------------DS-----Q-NVHLKSPTS-EYPCNI-PLVSN
-------------------LDAGNSKVLDLEESGPSQFK-NHLMPGKNNSDMDDK-V---
-----------------QEIKRSKVAP---DKKLHHKLVLPSHTPNVRRTKRIRLRPLEY
WRGERVDYHERPSGEVLP-------YISSKR-KAKENVGKVNKITNRK-RICLDSNER--
--IKVTLDIPVGDPLQPTEVKDPETREIIH-MDLIRLRDTYQFFIE-----HGEL

PF11699 // ENSGT00390000016737_Domain_2 (1136, 1219)

RVYKT
LDTPFFSTGKLILGPCEEKGRQHVGQDILVFYVSFGDLLCTLHETPYRITTGDSFYVPSG
NYYNIKNLLNEESVLLFTQIKR------------------------

----------MAASGL

PF15622 // ENSGT00390000016737_Domain_0 (17, 358)

DHLKN-----------GYRRRFCRPSRARDINTQQGQNVLEILQ
DCFEEQSLANDFGTNSTKSVLYSTHKIKDTCIQ-SRSK-----ECQKSHPKS----VPVS
SRKKE-A-----------SLQFVVEPSEASNRSVQAHEVRQKILAT-DVSSRNTSDSKKI
SS--RNVNDYHSDADEEFYLSVGSPSVLLDAKTSVS--Q------------NVIPSSAQK
RETYTFENSVNILPSSTEVSLKTKKRLNFEDKVMLKKIEIDNKVSDEECKTSEG-QERKP
S---GSSQSITRDSEYEIQRKAKKSFSTLFLETVKRKSKS--SPVVRHATTAPLHSC

ENSGT00390000016737_Linker_0_1 (358, 367)

P--
--PDDK

PF15620 // ENSGT00390000016737_Domain_1 (367, 740)

KVIEDEFIIDESDQSFASRSWITIPRKARPLKQ-RPISP-AESTALL-QTRK-S
-----------------------RERRHNILPKTLANGKHSHE-----------------
-------------------PHPVETSQSSDKTVLDTSYALTGETENDCRSTKYEMCSKDA
EKSSRS--KRTIKQKQRR-KFKAKPAEEQLDVGQSKDENMRMSHT-TQDKFQR--NTDRN
MEE---REEIGNDC----VSKKQMS-PVGSKK--SSA------RKDKGEAK-KK------
-HFSSES--------------------KN-KLV--PEEV-ISTFTRSRRISRRPSDWWVV
KSEESPVYSNS-SIRNELP

ENSGT00390000016737_Linker_1_2 (740, 1136)

VHRNSRQKS-AKKTNQSSKNIGEKTIPLKRQKTATKGSQRV
Q-K---FLNAKGSGG---TV-GHD-EISSCLLS---EPL---------ESDEEDLAKKKN
LDCSRS--ARSSNNE--------------DNVM-TAQ-HVPLKPQTS-GYTYNT-PTESS
-------------------LDSGERKTLVLEESGPSRLNNNYLMSGKNNNDVHEEEVHGS
S--------------DDS--KRSKVIP---KNRIHHKLVLPSNTPNVRRTKRTRLKPLEY
WRGERIDYQGRPSGGFVIGGILSPDTMSSKR-KAKE-NGKVDKKSNKK-RICLDNDERKT
-SLMVNLDIPLGDPLQPTRVKDPETREIIL-MDLVRPQDTYQFFVK-----HGEL

PF11699 // ENSGT00390000016737_Domain_2 (1136, 1219)

KVYKT
LDTPFFSTGKLILGPQEEKGKQHVGQDILVFYVNFGDLLCTLHETPYIISTGDSFYVPSG
NYYNIKNLLNEESVLLFTQIKR------------------------

----------MAAWGLDHLKN-----------DYRRRFCRPSRVPDINTEQGQNILEVLI
DCFEEKSLANDFSKNATKSVLYSTPKTKDICIQ-SSSKE---TQSQKSHPKS----GPVS
SRKKE-V-----------PLQLTVEPNEAVSKSVQDHEVHQKILAT-DVHSKNTSDLRKM
SS--KKLKDNHNEADEECYLSIGSPSD-LDIKASSL--Q------------KGSPSVAQK
RETYTSENSVNMLSSSTQISHKTRKRLSFEDKDVSKKVEIMNEVSEIEDKVSEGLQERKQ
S---GTSQKRIQDSEYENQPQARKSFSTLFLETVKRKSES--SSVVRHIATVPPHLSS--
--ANNMKLLEDEFIIDESDKSFVSQPWITIPRKTGPLKQ-HTVSP-AEST-VL-QRKK-S
-----------------------RENHDSVSSVALTSNKHPGK-----------------
-------------------AHPVEKSQPSEQKILGGSCALSDDVENNYKSTKYEIHSENA
KKSSGG--KRTIKQNQRT-KSKANVPEEEVDVRQSKDTNINISHT-VQDKLQR--NSDKN
MEE---GEEI-SVN----ISNNQLL-SVGSKKGSTNVPHKKNQKKDKE-CK-KK------
-HFSSGS--------------------KKNKIE--PEEL-TSTVTRSRRISRRPSNWWVV
KSEQSSFSSNSS-VRNELSVYHNSRQKPPAEKTKQSSKNIGKKAVPYKKQKRANEGSSEA
Q-K---VSCAKDSGG---S------------QN---ESL---------GSNEADLAKKKN
PNPSGD--TGSSKNQ--------------DT-M-AAQ-NVHRKSQKS-VYTCTT-PAKSN
-------------------LDSGEPGTSILEGSGPFRLK-NYLTSGKNNSDVDDNVVQEN
L--------------NDLRGEISDSTP---ESKMHHKLVLPSNTPNVRRTMRTRSKPLEY
WRGERIDYQSRPSGGFVIGGILSPDTVSSKR-KAKGNLGRIITTANRK-RICLENDERKN
-KFTVNLNIPLGDPLEPTRVKDPQTRETVL-MDLIRPRDTYQFCVE-----HDEL

PF11699 // ENSGT00390000016737_Domain_2 (1136, 1219)

KVYKT
LDTPFFSSGKLVLGPLQEKGKQHVGLDTLVFYVNLGYLLCTLHETPYIITTGDSFYVPSG
NYYNIKNLLNEESVLLFTQIKS------------------------

-----------NDPSLDHLKN-----------GYRRRFCRPSRARDLNTEQGQNVLEILQ
DCFEEKSLANDFSTNSTKSVPNSTRKIKDTRIQ-SPSK-----ECQKSHSKS----VPVS
SRNKE-A-----------SLQSVVESSEATNRSVQAHEVRQKILAT-DVSSKNTPDSKKK
SS--RNINDHHSEADEEFYLSVGSPSVLLDAKTSVS--Q------------NVIPSSAQK
RETYTFENSVNMLPSSTEVSVKTKKRLNFDDKVMLKKIEIDNKVSDEEDKTSEG-QERKP
S---GSSQNRIRDSEYEIQRQAKKSFSTLFLETVKRKSES--SPIVRHVATAPPHSCP--
--PDDTKLIEDEFIIDESDQSFASRSWITIPRKAGPLKQ-RTVSP-AESTALL-QGRK-S
-----------------------REKHHNILPKTLANDKHSHK-----------------
-------------------PHPVETSQPSDKTVLDTSHALIGETENNYRSTKYEMYSKNA
EKPSRS--KRTIKQKQRR-KFMAKPAEEQLDVGQSKDENIHTSHI-TQDEFQR--NSDRN
MEE---REEMGNDC----VSKKQMP-PVGSKK--SST------RKDKEESK-KK------
-RFSSES--------------------KN-KLV--PEEV-TSTVTRSRRISRRPSDWWVV
KSEESPVYSNS-SIRNE-PVPHNSRQKS-AKKTKESSKNIRKKTIPLKRQKTANKQRQKL
N-----------ACS---GI-GHD-EISRCSLS---EPL---------ESDEADLAKKKN
LDCSRS--TRSSKNE--------------DDIM-TAQ-NVPLKPQTS-GYTCNI-PTESN
-------------------LDPGEHKTSVLEESGPSRLNNNYLMSGEN--DVDDEEVHGS
S--------------DDS--KQSKVIP---KNRIHHKLVLPSNTPNVRRTKRTRLKPLEY
WRGERIDYQGRPSGGFVISGILSPDTISSKR-KAKENIGKVDKKSNKK-RICLDNDERKT
-NLMVNLGIPLGDPLQPTRVKDPETREIIL-MDLVRPQDTYQFFVK-----HGELKVYKT
LDTPFFSTGKLILG

PF07883 // ENSGT00390000016737_Domain_2 (1155, 1216)

PQEEKGKQHVGQDILVFYVNFGDLLCTLHETPYIISTGDSFYVPSG
NYYNIKNLRNEESVLLFTQIKR------------------------

----------MASFHL

PF15622 // ENSGT00390000016737_Domain_0 (17, 150)

DHLKNY------------HRRFCRPSRAPNIHAKQGQNVLEVLQ
DCFDEQSKASFLNGLSELSLLSFTPKAKDTRSQ-SAGK-----ECQASHSQS----VPVS
SGRKD-A-----------SPQVTAEPSEATLGSG--------------------------
-C--KKTNESRSATKDHLYLPGGSPVVPLYEKMSES--Q------------NVISSLSQR
RGAYNSRNSIDTKSSYTDISLKTRKRLNFEGKDSLNKAEVENNVLEV----SEGQ-EGTS
S---ETSQKRAQDLTYEIQPQSRKSFSTLYLETVKRKSES--SSSVRHTAAISPHSS---
--PKART

PF15620 // ENSGT00390000016737_Domain_1 (368, 737)

LLEDEFIIEESGRSFESQPWVKIPRKDRHQSH-HLPSP--ENMVAA-KDKK-P
-----------------------EEKPHSVSATSLMHDTQFHK-----------------
-------------------ASPIEKSQPSVEKIL--GTSYIDELESDYSSTENKIHSENA
KKTSES--KRTLRQKKQR-VSKPKVVEEQLDMGQGKKKKRNMSNT---DKLQL--NSKRN
MED---CEEARNKP----IPKKQIS-PVEKKKKKHSI------QKDMEKSR-KK------
-SFSGGS--------------------KD-KQE--QE------IVRSGRISRCPSEWWLV
KPEKGSFDRSF-SRES

ENSGT00390000016737_Linker_1_2 (737, 1136)

ILSVVHHNGKKR-TR-KSQLSKNTGKKPSPSKRRKT--ESSSRV
Q-K---SLNTKGSRS---V--SHD-EIS-GSQS---EPL---------EN-EADSTQKKS
LDISGP--TGGSKYQ--------------NSVM-TSQ-NVHLKSHTG-ENTRKS-SMKSN
-------------------SNAGEPKNSIWEESGPSRFK-DHVMSKSNNSDMGDEKDQE-
----------------NLRIRSSNVLP---DSSIHHKLVLPSNSPNVRRTKRIRLKPLEY
WRGERIDYQERPSGR-VVIGIVSPPPVSPIK-KAKRNLDKVNKKANKK-RIHRDNHE---
---MVNLDKPLGNPFEATLAKDPETREIVP-MDLIRPRDTYQFFVE-----QHGL

PF11699 // ENSGT00390000016737_Domain_2 (1136, 1219)

KVFKT
LDTAVFSTGKLILGPYEEKGKQHVGQDILVFYVNFGDLLCTLHETAYMISTGDSFYVPSG
NHYNIKNLLNVESCLLFTQIKR------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-EIPSSLDHSLADVSKPAIVLDPVTNKEVL-LGELNGSSCVSYHRS-----DDAAE

PF11699 // ENSGT00390000016737_Domain_2 (1137, 1200)

IYKD
LSTSYFATGVLVLKPLKVKGRQFVYTNTIAFRILHGQVIVTIHKTSYYLATGDSFYVPAG
----------------------------------------------

----------MAASGL

PF15622 // ENSGT00390000016737_Domain_0 (17, 358)

DHLKN-----------GYRRRFCRPSRAHDVNTEQGQNVLEILQ
DCFEEKSLANDFSTNSTKSVPNSTRKIKDTCIQ-SPSK-----ECQKSHPKS----VPVS
SKKKE-A-----------SLQLVVEPSEATNRSVQAHEVHQKILAT-DVSSKNTPDSKKM
SS--RNINDHHSEADEEFYLSVGSPSVLLDAKTSVS--Q------------NVVPSSAQK
RETYTFENSVNMLPSSTEVSVKTKKRLNFDGKVMLKKIEIDNKVSDEEDKTSEG-QERKP
S---GSSQNRIRDSEYEIQRQAKKSFSTLFLETVKRKSES--SPIVRHAATAPPHSC

ENSGT00390000016737_Linker_0_1 (358, 366)

P--
--PDD

PF15620 // ENSGT00390000016737_Domain_1 (366, 740)

TKLIEDEFIIDESDQSFASRSWITIPRKAGSLKQ-RTISP-AESTALL-QGRK-S
-----------------------REKHHNILPKTLANDKHSHK-----------------
-------------------PHPVETSQPSDKTVLDTSYALIGETVNNYRSTKYEMYSKNA
EKPSRS--KRTIKQKQRR-KFMAKPAEEQLDVGQSKDKNIHTSHI-IQDEFQR--NSDRN
MEE---REEMGNDC----VSKKQMP-PVGSKK--SST------RKDKEESK-KK------
-RFSSES--------------------KN-KLV--PEEV-TSTVTKSRRISRRPSDWWVV
KSEESPVYSNS-SVRNELP

ENSGT00390000016737_Linker_1_2 (740, 1136)

VHHNSSQKS-TKKTNQSSKNIRKKTIPLKRQKTATKGNQRV
Q-K---FLNAEGSGG---IV-GHD-EISRCSLS---EPL---------ESDEADLAKKKN
LDCSRS--TRSSKNE--------------DNIM-TAQ-NVPLKPQTS-GYTCNI-PTESN
-------------------LDSGEHKTSVLEESGPSRLNNNYLMSGKN--DVDDEEVHGS
S--------------DDS--KKSKVIP---KNRIHHKLVLPSNTPNVRRTKRTRLKPLEY
WRGERIDYQGRPSGGFVISGVLSPDTISSKR-KAKENIGKVNKKSNKK-RICLDNDERKT
-NLMVNLGIPLGDPLQPTRVKDPETREIIL-MDLVRPQDTYQFFVK-----HGEL

PF11699 // ENSGT00390000016737_Domain_2 (1136, 1219)

KVYKT
LDTPFFSTGKLILGPQEEKGKQHVGQDILVFYVNFGDLLCTLHETPYILSTGDSFYVPSG
NYYNIKNLRNEESVLLFTQIKR------------------------

----------MAASGL

PF15622 // ENSGT00390000016737_Domain_0 (17, 358)

DHLKN-----------GYRRRFCRPSRARDINTEQGQNVLEILQ
DCFEEKSLANDFSTNSTKSVPNSTRKIKDTCIQ-SPSK-----ECQKSHPKS----VPVS
SKKKE-A-----------SLQFVVEPSEATNRSVQAHEVHQKILAT-DVSSKNTPDSKKI
SS--RNINDHHSEADEEFYLSVGSPSVLLDAKTSVS--Q------------NVIPSSAQK
RETYTFENSVNMLPSSTEVSVKTKKRLNFDDKVMLKKIEIDNKVSDEEDKTSEG-QERKP
S---GSSQNRIRDSEYEIQRQAKKSFSTLFLETVKRKSES--SPIVRHAATAPPHSC

ENSGT00390000016737_Linker_0_1 (358, 366)

P--
--PDD

PF15620 // ENSGT00390000016737_Domain_1 (366, 739)

TKLIEDEFIIDESDQSFASRSWITIPRKAGSLKQ-RTISP-AESTALL-QGRK-S
-----------------------REKHHNILPKTLANDKHSHK-----------------
-------------------PHPVETSQPSDKTVLDTSYALIGETVNNYRSTKYEMYSKNA
EKPSRS--KRTIKQKQRR-KFMAKPAEEQLDVGQSKDENIHTSHI-TQDEFQR--NSDRN
MEE---HEEMGNDC----VSKKQMP-PVGSKK--SST------RKDKEESK-KK------
-RFSSES--------------------KN-KLV--PEEV-TSTVTKSRRISRRPSDWWVV
KSEESPVYSNS-SVRNEL

ENSGT00390000016737_Linker_1_2 (739, 1136)

PMHHNSSRKS-TKKTNQSSKNIRKKTIPLKRQKTATKGNQRV
Q-K---FLNAEGSGG---IV-GHD-EISRCSLS---EPL---------ESDEADLAKKKN
LDCSRS--TRSSKNE--------------DNIM-TAQ-NVPLKPQTS-GYTCNI-PTESN
-------------------LDSGEHKTSVLEESGPSRLNNNYLMSGKN--DVDDEEVHGS
S--------------DDS--KQSKVIP---KNRIHHKLVLPSNTPNVRRTKRTRLKPLEY
WRGERIDYQGRPSGGFVISGVLSPDTISSKR-KAKENIGKVNKKSNKK-RICLDNDERKT
-NLMVNLGIPLGDPLQPTRVKDPETREIIL-MDLVRPQDTYQFFVK-----HGEL

PF11699 // ENSGT00390000016737_Domain_2 (1136, 1219)

KVYKT
LDTPFFSTGKLILGPQEEKGKQHVGQDILVFYVNFGDLLCTLHETPYILSTGDSFYVPSG
NYYNIKNLRNEESVLLFTQIKR------------------------

----------MATSGLDHLKN-----------GYRRRFCRPCRAPDINPEQGQNILEILQ
NYFEEKSFVNDFSSDSTKSQLYSTPKVENIYIQ-SSSQ-----KCQNSQPKS----IPVS
SRKKE-A-----------SLQFIVEPSEAASRSDQQYRFNLIISVY-PIAFARIPEP--I
LS--HNGDSRHSYSKQFFSISLFCLSIFVLFLILYK--A------------STLPTE---
AQVPSCXNSLNTLSSSAEISLKTKKRLNFEDKVILKALEVESKV--EQCNVSERQQERKP
A---ETSQKRIQDPEREIQAHAKKTFSTMFLETVNRKSES--SSIVRHLATVAPHLSP--
--PNDTKLIEDEFVIDESDRSFAIQSWITIPRKAGPVKQ-GTVSP-AETTALL-QGKE-S
-----------------------REKHSHVSPKTLASDKASCK-----------------
-------------------AQPLEKSQPSGQERLGTSCM-----ENDSRSTKREIHSQD-
KKSSGS--KKAIEQKQTR-KLKVNVVEEQLHMEQSDDENLNTSHI-AQNKFQR--NSLKS
MEE---CEKMRNDH----VSKKQMP-PVESKK--SSS------RKHEEESK-KK------
-RFSTES--------------------KN-KVI--PEEV-TLTVTRSRRISRCPSNWWVV
KSEQRPANSNS-SIRNELSAHQNNRQKP-TKNKNQSSKNIGEKNIPLKRKKTATQGSLRM
Q-T---FSNAESSED----T-GLD-KISSCSQI---EPL---------ENKKANLAKKKD
LHNHFG-CTGSSEDQ--------------DGTM-STH-NFPLKTKTS-SYICTT-PIDSN
-------------------LDSEKPNASVLEESGPSRHK-NYLMSRQNNSDVNDEKVQES
S--------------DDSRLKRFKMTP---NNKVHHKLVFPSNTPNVRRTKRIRLKPLEY
WRGERIDYQVRPSGALVIGGILSPHTVSSTR-KTKRNMENVKRIANQK-RICPDNDERRS
-RLMVNLDIPLGDPLQPTRVKDPQTREIIL-MDLVRPRDTCQFFVK-----HGELEVYKT
LDTPFFSTGKLIIG

PF07883 // ENSGT00390000016737_Domain_2 (1155, 1215)

PHQEKGKQHVGSDILIFYVNFGYLLCTLHETSYIITTGDSFYIPSG
NYYNIKNLLNEESTLLFTQIKR------------------------

------------GDGLDHLKI-----------SYRTRFCCTSRVPDTDLWQGQNILENIQ
DCFEEKSSDTGFSTNPGSPTLCSTPCKLKNDSYSSPNK-----EDQISPSKS----NRIS
SVKKNTS--PFS------QQPAILQNQTN-SSSALHPEITQKFSQGDLIGLRNTPNLRYS
-SGAEERNKIPNEVVEEFYLTVGSPGLLAKETEI-LPLPQ-----------QAIPTTQ-D
RRSRVFGNSVIQQSLLPKSSLKTKKSLNSEDIVVWSAVK----KADKGVKESERQQKRRQ
S---ESSEQTIQDPKEKIPPKTDTDFSTLLLQAAKKKKKKKKVALNMRVSSPKTCSPSP-
-PPNDLELSNDEFIIDESD-CSVSQDWILIPNKNSKSVKQRKADP-VESFQDP-ERKKAR
IEQQQGGNCNTA------------------------SDKHSDTENGISD--FTVGKKTSK
SI----------------------------------KKKLSPEMGNASKSTRHTLYSEET
EQFFEK--KKTVMQHQSEN-CMDQNGVYKHKVGGKHQKRFNVSQT-NQDKLQSASD--RS
LGQ----EEERA---ESCHSTKRKPSAAAS----QQ-----IQKKGLNKIRSKNQQMSMK
REITLKP---------------------------NQSQ--KFTITRSQRISKRPSNWWVV
TTEESKYISNKL-TMRESPVSLKKKTKPSKEPKKIPLKTLEKDTIPLKQQELPVCAKPKK
----------------ASILNKKKRKKLSYSSDENCDIALTIPKLDEQEGSLKETPRKK-
NLCSSR--TL-TNQRQRNSIHT--AEPPKGSNS-EDQ-TDNLTPAVLTSD-----SKTF-
-------------------------LTSNMEESGPARIRNNVLTSANNKIF-GDEQEIKG
S--------------ADSSQERSWIQNKQVHNFSMHQLNPPDKTPCVRRTTRIKMKPLEY
WRGERVDYEGTLLDGFAASGTISNDRVSPRE-KSNRKREKAHT------DSCEDEQK---
KKAIAALNVSLGDPFKPTCVFDPGREQMVF-RDLVKLKGTHEFCVQ-----DDTL

PF11699 // ENSGT00390000016737_Domain_2 (1136, 1219)

KMFKI
LNTSLFATGTLILEPFKEKGKQYVCSDTVVFFIVSGDLICTLHETSYNLTTGDIFYVPSG
NFYNIKNLLNERSILLFTQIKS------------------------

---------MASSFHL

PF15622 // ENSGT00390000016737_Domain_0 (17, 358)

DHLKNY------------RRRFCRPSRAPNINTRQGQNVLEILQ
DCFEEQNS--------TESLLCTTPKAKDNCNQ-SAGK-----EASHS--ES----VPVS
S-RKK-G-----------TLKVAAEPSEAACGSVQANEVHQKILAT-DNVSKSTVDSNSM
SS--EKTNGHHRATNDNFCLSRGSPVVLLDAKTSEL--Q------------NVISSLGQR
RVTSVLRNSVDKKSSNTDISLKTRKRLNFEDKSILNQAEIVNSVLEVEDNISEGQ-EEIS
S---GTFQERGQDLSYEIQQRSKKSFSALYLEAVKRKNES--SSI-VRHTAALPLSS

ENSGT00390000016737_Linker_0_1 (358, 367)

P--
--PNEA

PF15620 // ENSGT00390000016737_Domain_1 (367, 740)

KLLEDEFIIDESDRNFASQPLVTIPRKGRHLRH-NLPSS--ENIVTP-EDKK-L
-----------------------REKP-----TTVISDSQPQK-----------------
-------------------SPSIGKSQPPVENIL--GTSCTDELESDCRSTENKMHSENA
KKTSGC--KRTVRQKQRR-VSKPNVVEEKLNVGQGKKGKRNMSNI-GQDKLQV--NSKRT
KKD---CEDSRNEP----TPKKQMP-PIENKKNQHSN------PKDRKKSG-KK------
-CFSGES--------------------RN-TFV--PEEV-SVSVRRSHRVSQHPSEWWLV
KPEKGSVDRSS-SRANESL

ENSGT00390000016737_Linker_1_2 (740, 1136)

VVHRNRKKR-TK-KNQLSKNAGKKPLPSKRQKT--ENSSRV
Q-K---SLNVKGSRE---SVSSHD-EIS-GNQS---KPL---------ENNEADLTLKRS
LNISGP--TGGSKHQ--------------SSIM-TSQ-NIHLKSHTG-KYTT-R-SMESN
-------------------SGSGEPKNSIWEESGPSRFK-DCVLSGSNNFGVSDEKEQES
L---------------DLRISTSNELP---DTNIHHKLVLPSNSPNVRRTKRIRLKPLEY
WRGERIDYQERPSGR-IVIGIVSPAPVSPKR-KAKGNLGKVTKKANKK-WIRPENHEKD-
-RLVVNLDIPLGDPFQATLAKDPETREIIP-MDLIRPRDTYQFFVE-----QHGL

PF11699 // ENSGT00390000016737_Domain_2 (1136, 1219)

KVFKT
LDTAFFSTGKLVLGPYEEKGKQHVGQDILVFYVNFGELLCTLHETPYMITTGDSFYVPSG
NHYNIKNLLNVESCLLFTQIKR------------------------

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------------------------------------------------------------
----------------------------------------------------S-EKEKTK
NKKAKKRKV---EVKALTK---HEQDHLDVEAFDLKEMSA----------SDSVSNSEEN
VLASQSLKSTHIGKTKKDA---FRQDSPN-QKK---NTSRKPGAE-------ELML----
--SW----TGLETKPSDEEQCK-----TRM-PSEDLPMPSSGHEE-EQT--VSLKKSLKS
SKNLQLSSKASQQLVKKTQTAKQKLPKVKVAKRGTVSPRKKLKISVQKSSN-KKPQLQRE
ESSDSEP------EEELEREPVEL----NEVCTTPLHQKLETPVIQKLTKSEKPR-----
---------NVI-HTSESPGGA---N--N----RTPLK---ALQDPVESVKNPGKK----
R-SAKS------SGKKPKKIPCRI-NKALRSSPEGPESQ--TDSDS---SSVQDTARKK-
QKLPDV--KIKSNKRKH------DRQHGPQGIF---------------------------
-----------------------------FLCSGPVLEDGDEFACSTKPPE-Q---DDIS
S--------------DNSEDSNYKLRHLLSDEIVKHKIVMPSNTPNVRRTKRIRLRPLEY
WRGERINYTMKPSGGLVISGLVHPETESPRK-SKKRKD-CPK----HK---THKTNR---
GEIPASLDHSLADASKPAIVLDPVTKREVH-LDCINTANDQNYFFK-----DEAVE

PF11699 // ENSGT00390000016737_Domain_2 (1137, 1219)

IQKK
LSTSLFATGRLILKPYKEKGHQFVDMDTIAFHIIHGKVIVTLHETSYYLTAGDCFYVPAG
NGYNIRNLLNEESVLLFTQLKDSARTPMAAEFCSTTNEDWS-----

----------DLLFFQ

PF15622 // ENSGT00390000016737_Domain_0 (17, 358)

DHLKN-----------GYRRRFCRPSRARDINTQQGQNVLEILQ
DCFEEQSLANDFSTNSTKSVLYSTHKIKDTCIQ-SRSK-----ECQKSHPKS----VPVS
SRKKE-A-----------SLQFVVEPSEASNRSVQAHEVRQKILAT-DVSSKNTSDSKKI
SS--RNVNDYHSDADEEFYLSVGSPSVLLDAKTSVS--Q------------NVIPSSAQK
RETYTFENSVNILPSSTEVSLKTKKRLNFEDKVMLKKIEIDNKVSDEECKTSEG-QERKP
S---GSSQSITRDSEYEIQRKAKKSFSTLFLETVKRKSKS--SPVVRHATTAPLHSC

ENSGT00390000016737_Linker_0_1 (358, 367)

P--
--PDDK

PF15620 // ENSGT00390000016737_Domain_1 (367, 740)

KVIEDEFIIDESDQSFASRSWITIPRKARPLKQ-RPISP-AESTALL-QTRK-S
-----------------------RERRHNILPKTLANGKHSHE-----------------
-------------------PHPVETSQSSDKTVLDTSYALTGETENDCRSTKYEMCSKDA
EKSSRS--KRTIKQKQRR-KFKAKPAEEQLDVGQSKDENIRMSHT-TQDKFQR--NTDRN
MEE---REEIGNDC----VSKKQMS-PVGSKK--SSA------RKDKGEAK-KK------
-HFSSES--------------------KN-KLV--PEEV-ISTFTRSRRISRRPSDWWVV
KSEESPVYSNS-SIRNELP

ENSGT00390000016737_Linker_1_2 (740, 1136)

VHRNSRQKS-AKKTNQSSKNIGEKTIPLKRQKTATKGSQRV
Q-K---FLNAKGSGG---TV-GHD-EISSCLLS---EPL---------ESDEEDLAKKKN
LDCSRS--ARSSNNE--------------DNVM-TAQ-HVPLKPQTS-GYTYNT-PTESS
-------------------LDSGERKTLVLEESGPSRLNNNYLMSGKNNNDVHEEEVHGS
S--------------DDS--KRSKVIP---KNRIHHKLVLPSNTPNVRRTKRTRLKPLEY
WRGERIDYQGRPSGGFVIGGILSPDTMSSKR-KAKE-NGKVDKKSNKK-RICLDNDERKT
-SLMVNLDIPLGDPLQPTRVKDPETREIIL-MDLVRPQDTYQFFVK-----HGEL

PF11699 // ENSGT00390000016737_Domain_2 (1136, 1213)

KVYKT
LDTPFFSTGKLILGPQEEKGKQHVGQDILVFYVNFGDLLCTLHETPYIISTGDSFYVPSG
NYYNIKNLLNEESMKDQPSLNMCVYICICENR-------FV-----

----------MADSGLDHLKN-----------DYRRRFCRPSRAPDINMQVGQNILEILQ
DCFEEESPANDFSGNSTKSVVYLTPKTKDLCVK-SPSKE---CQ--KSHPKS----IPVS
SRKKE-A-----------SLQFLVEPSEAANRSVQAHEVHQEILAT-DVGAKNTPDSRKM
SS--KKVKDHHNEVSEEFYMSVGSASVLSDAKTSVS--K------------NAVASVVEK
RETHSLKNSISMLSSGTESSHKTKKRLNFD--DVLKKVAIESKVSEIEDKVSEGPQEKKP
S---GASQKRIQDSEYEIQPEAKKSFSTLFLETVKGKSES--SPIVRHIATTPPHSSV--
--ASDMKLLEDEFIIDESDGSFASRSWITIPRKAGPLKQ-REVSP-AESTTLL-QSRK-S
-----------------------REKHHNVSPMTLTSDRHSGK-----------------
-------------------AHQVEKSQPSEQRILCRSCTLTDEMENNYRSTEYEVYSKNA
RKSSGN--KRTVNQNQRR-KFKANVVEEQVDMEHSKDKNINMSHV-AQDKLQR--NSGSN
MKE---CKEMSNVH----ISKKQMP-TVGNEKSSTN-------KKDKK-GK-KK------
-HFSNES--------------------KKNKLV--PEEV-TLTVTRSRRISRRPSNWWVV
QSEQNPIYSNSS-IRNELSVYHNSRQKP-VEKSSQSSKNIGRKTIPRKGQKRATQGSSKR
Q-K---FLNAKDSGG---IT-DHD-EIPSCSHN---ESV---------ESDKADLAKKKN
LDHSGD--TGSPKDQ--------------DNVM-TSQ-NVHLKSQTS-GYTCKT-PAEFN
-------------------LDSGEPKTSVLEESGPSTPK-NYLTSEMNNSEVVDKEVQES
S--------------GKVKG--SKVTL---ENKIHYKIVLPSNTPNVRRTKRTRLKPLEY
WRGERIDYQGRPSGGFVIGGILSPDTISSKR-KAKGSMEKVNEIVNRK-RICLDNNERKN
-KLVVNLNIPLGDPLQPTRIRDPETREIIL-MDLVRPRDTYQFIVE-----HGEL

PF11699 // ENSGT00390000016737_Domain_2 (1136, 1219)

KVYKT
LDTPFFSTGKLILGPHQEKGKQHVGSDILVFYVNFGDLLCTLHETPYMITTGDSFFVPSG
NYYNIKNLLNKESVLLFTQIKR------------------------

----------MAVSGL

PF15622 // ENSGT00390000016737_Domain_0 (17, 358)

DHLKN-----------DYRRRFCRPSRAPGINTEQSQNMLEILQ
NCFEEKSLTD--VTNSPESVLYSTLKIKNSFIQ-SPSK-----DCQISFPVSSRKSLPFS
S-RKK-A-----------SLQGVIEPSEAASRSVQVHEINQKVPEA-DVGSKSTPDLGKK
SD--KKTNGLCAETDEEFYISVGSPSVLLHGKPSES--Q------------NAIS-SAQK
RETHTSGN---ILSSGTEISLKIRKRLNFEDKDTFRKVERETDKSKVENKILGQ-EEKKV
S---ETSSKRLQDTEYEIKSQAKKSFSTLFLETIKRNNES--SSVVRHTSTAPSHSS

ENSGT00390000016737_Linker_0_1 (358, 366)

P--
--PSD

PF15620 // ENSGT00390000016737_Domain_1 (366, 739)

TKLLEDEFIIDKSDRSFTNQSWITIPRKGRSWNQ-HTVSS-TGSAAIL-QGKK-A
-----------------------RE-HQSVSPVTLTGDKYLHK-----------------
-------------------THPEEKSEPSCEQKRSINCTVIDKLENSHRSIK--MYSEKA
ERKKGKRKNKTAKQEQKK-KFKTNVVEEQLDTGQSEEEN--ISDI-TQDKIPR--NSERT
IED---CEKMRNDH----SATKGMP-PVENMKTKCRT------KKDRKESR-KK------
-HFSSES--------------------KRKKLE--PEET-TSFVTRSHRVSRRPSDWWVV
HSKESPVHSNS--PRNDV

ENSGT00390000016737_Linker_1_2 (739, 1136)

SLYHSSRQKL-AEKTNQSSK---KKTVQSKKQKASTQGNSRV
Q-Q---FSNVKGSGG---IT-DH--EVSSCPQN---EPM---------ESSEADLTTEKN
LDSSSDRTTKHSKDR--------------GGVM-CTQ-NVHLQSQTNEEDTCAA-PTESN
-------------------LDSGEHKTSVLEESGPCRLK-NYLKSRKNISDMNNE-VQES
LDNLR--------------VERFEVAP-WNKVKMHHKLVLPSNTPGVRRTKRIRSKPLEY
WRGERVDYHETASGGFVIGGILSPKTVTTER-KARENVGKVNKIEDRK-RICLDNMERKS
-ELVLNLDIPVGDPFQPTQVKDPETKKVIL-MDLIRPRDTYQFFVS-----HGEL

PF11699 // ENSGT00390000016737_Domain_2 (1136, 1219)

KVYKT
LDTPFFSTGKLILGPYEEKGRQHVGEDTLVFYVNVGDLLCTLHETSYIIKTGDSFYVPSG
NYYNIRNLLNEESVLLFTQIKR------------------------

----------MAASGL

PF15622 // ENSGT00390000016737_Domain_0 (17, 325)

DHLKN-----------GYR-RFCRPSRARDINTEQGQNVLEILQ
DCFEEKSLANDFSTNSTKSVLNSTRKIKDTCVQ-SPSK-----ECQKSHPKS----VPLS
SRKKE-A-----------SLQFVVEPSEATNRSVQAHEVRQKILAT-DVSSKNTPDSKKM
SS--RNINDHHSEADEEFYLSVGSPYVLLDAKTSVS--Q------------NVIPSSAQK
RETYTFENSVNMLPSSTEVSLKT-------------------------------------
----------------------KK

ENSGT00390000016737_Linker_0_1 (325, 366)

SFSTLFLETVKRKSES--SPIVRHGGIAPPHSCP--
--PDD

PF15620 // ENSGT00390000016737_Domain_1 (366, 739)

MKLIEDEFIIDESDQSFA-----------GPLKQ-RTISP-AESTALL-QDRK-S
-----------------------REKHHNILAKTLANDKHSHK-----------------
-------------------PHLVETSQPSDKTVLDTSYALTGETENDCRSTKYEMYSKNA
EKSSRS--KRTIKQKQRR-KFMAKPAEEQLDVGQTKDENIHMSHI-TQDKFQR--NSDRN
MEE---REEMGNDC----ASKKQMP-PVGSKK--SST------RKDKEESK-KK------
-RFSSES--------------------KN-KLL--SEEV-TSTVTRSRRISRHPSNWWVV
KSEESPVYSNS-SIRNEL

ENSGT00390000016737_Linker_1_2 (739, 1136)

PLHPNSRQKS-AKKTNQSSKNIGKKTIPLKRQKTATKDSQRV
Q-K---FLNAKGSGC---II-GHD-EISSCLLS---EPL---------ESDEADLAKRKN
LDCSRS--TGSSKNE--------------DNIM-TAQ-NVPLKPQTS-GYICNT-PTESN
-------------------LDSGEHKTSVLEESGPSRLNNNYLMSGKNNNDVDDEEVPGS
S--------------DDS--KRSKVIP---KNRIHHKLVLPSNTPNVRRTKRTRLKPLEY
WRGQQIDYQGRPSGRFVISGILSPGKISSKR-KARENIG-------KK-RICLDNDERKT
-SLMVNLGIPLGDPLQPAMVKDPETREIIL-MDLVRPQDTYQFFVK-----HGEL

PF11699 // ENSGT00390000016737_Domain_2 (1136, 1219)

KVYNT
LDTPFFSTGKLVLRPQEEKGKQHVGQDILFFYVNFGDLLCTLHEIPYIISTGDSFYVPSG
NYYNIKNLLNEESVLLFTQIKR------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------S-NTRLSN-I
Q--------------DHPTHFSSQCFQYIKSISVSYSLVLPTNTPNVRRTKRMRIKPLEY
WRGERVKYRTRPSGGFVFHGIISPEQKEPIK-PKSKKTTNPVM---E----LGMSSL---
QYIYNMPESSLQDPPQPAVVFDVESNQGVL-LQCVNTGTSHLHFIN-----NEAVS

PF11699 // ENSGT00390000016737_Domain_2 (1137, 1219)

IYKY
LTTPSFSAGKMILKPLKEKGYQYSYTDTLVFNITKGKILLTLYDQYYHLTVGDYFFIPPG
NVYNIRNLLNKECIILFTQLKG------------------------

----------MAASGL

PF15622 // ENSGT00390000016737_Domain_0 (17, 358)

DHLKN-----------DYRRRFCRPSRGPDINTEQGQNILEILK
DCFEEKSLANDLSTNSTKSVLYSTSQIKDICIQ-SPSKEKSHLQCQKSHQKS----IPVS
SRKKE-A-----------SLQFTIEPSETASKSVQAHAVCQKNLST-DVDSKNTPGFKKM
TN--GELNSHHSEADEEFYLSVGSPSAVLDAKTSVS--Q------------NAIPSIAQK
RETYTFENSVNMLSSSTEISLKTKKRLNFEDKVILKKVEVENKESGENKISERQ-QEKKP
V---RISQKRIQDSEYETQAQSKKSFSTLFLETIKR-SES--SPIVRHLTTAPPHLP

ENSGT00390000016737_Linker_0_1 (358, 366)

P--
--PND

PF15620 // ENSGT00390000016737_Domain_1 (366, 740)

MKLIEDEFVIDESDRSFADRSWITIPRKAGPVKQ-RTISP-AENTALL-QGKE-S
-----------------------REKHHNVSPKTLASDKDSNK-----------------
-------------------AHPVENSQPSGQQKLGTSCPLTDEMENNNRSTKYEIYSQTA
EKSPGS--KKAIKQKQRR-NFNANGADELLDRGQSNVENLNMSHI-AQSTFQR--NSDKN
MEE---REELRNDH----ISKKQVI-HVASKK--SST------RKVKEDSK-KK------
-RFSNES--------------------KNSKVV--PEEV-TSTVTRSRRISRHPSDWWVV
KPDQSPVYSNS-PIRNELS

ENSGT00390000016737_Linker_1_2 (740, 1136)

VHHNSRKKP-TEKNNQLSKNIEKKTIPFRRQKTATEDSSKV
Q-K---FLNAKGSEG---II-DHD-DISGCSQI---EPL---------ESDKADLVKKKN
LDNHSG--STGNSKD--------------QDDM-TAH-NVHLKSKIS-SYTCKT-PTDSN
-------------------LVSGESEAPVLEESGPSRIK-NYLMSVKKNSDVNDEKVWES
S--------------DDSRVKRSKVIP---ENKIHHKLVLPSNTPNVRRTKRIRLKPLEY
WRGERIDYKGRPSGGFVISGILSPDIIPSKR-KAKGNEGKVNKIAMQK-RICLDNDERKS
-RLMVNLDIPLGDPLQPTRVKDPETRDIIP-MDLIRPRDTYQFFVT-----HGEL

PF11699 // ENSGT00390000016737_Domain_2 (1136, 1219)

KVYKT
LDTPLFSTGKLVLGPHQEKGKQHVGPDILVFYVNFGDLLCTLHETSYIITTGDSFYIPSG
NYYNIKNLLNEESVLLFTQIKR------------------------

-----------MAERL

PF15622 // ENSGT00390000016737_Domain_0 (17, 97)

DHLKK-----------YYRARFCGQGGK-KINIQPGQNVLKYIQ
DCFECDDTDV--TINSPNATCSSTPLVRNQERTSTQS-----------PRPD----AGL-
--------------------TIVVGNRTCHSTVSLPATPAETV----------------R
SK---------GEPC-VFCPEPGRNSRIADSIKTDSPVHR------------GET-----
-----------------------------QVLT----FK----DAEGLC----------E
S---PA---KLSDPEDDP----GVVGSPLLVEEAK-------TPVQTCTVSIAPSSPSPV
KDHNVEIESDCEFLIDESG-CLSFKSWFSIPRKNRKSQKDGSAAP-VLKSQSS-DKEKTA
DKKGKNMNV---QAEVHSEQKTK---NV---------RVQRDL-KRTSESHPVSSDSEGK
VLKSKMQSSTHAGKSKKDA---LKGSSKH-RKK---MS-YESEA--------EQLM----
--LS-----GLDSETSDEEQKI-----RRVMPREDLAVPSAEHQQ-EQM--LSSKKNLTP
CKYQQSASKAYQRSVHKKQT-KQTLANDTV----LKSQRKKLKKSGKRNGN-KNPEPRRW
KSSDSEP-----GEEGLEREPLES----NEMFTSPPHQELQTSVLQKLAKSEKAE-----
---------KVL-HALESVTDV---N--N----KTPLK---AVELLQHLVDSMKN-SEKK
RSSVTS------SGKMLKKVHHRA-HKRACSITRDSEPQNTTDSDS---SSAPEVARKK-
RRQSAV--RAS-KKPKSNRHQRLQHSPAAE-KA---------------------------
----------------------------MGPESGLVLEHSEKYTSPSKHCE-E---NNES
S--------------DNSEDLHCQIKNLLSDEIGRQKIVLPSNTPNVRRTKRIRLKPLEY
WRGERVTYTLKPSGRLLISGIAGAEAEPHMK-NKL-KSR-HK----K----KRAKTR---
SEVVKCLDIPLADASKPTSIVDPVTNQEVL-LECINSGSSHSCFFE-----DES

PF11699 // ENSGT00390000016737_Domain_2 (1135, 1219)

IKVYKS
LNTSDFAAGKLILKPLKEKGHQFVHMDTIAFYVIRGQIITTLHKTSYYLTSGDYFYVPAG
NGYNIRNLLNEESVLHFTQLKNDR-APVGAELCSVTNENWSLEGKS

----------MAASGL

PF15622 // ENSGT00390000016737_Domain_0 (17, 358)

DHLKN-----------GYRRRFCRPSRARDINTQQGQNVLEILQ
DCFEEQSLANDFSTNSTKSVLYSTHKIKDTCIQ-SRSK-----ECQKSHPKS----VPVS
SRKKE-A-----------SLQFVVEPSEATNRSVQAHEVRQKILAT-DVSSKNTSDSEKM
SS--RNINDYHSDAGEEFYLSVGSPSVLLDAKTSVS--Q------------NVIPSSAQK
RETYTFENSVNTLPSSTEVSLKTKKRLNFEDKVMLKKIEIDNKVSDEEYKTSEG-QERKP
S---GSSQNITRDSEYEIQRKAKKSFSTLFLETVKRKSKS--SPVVRHAATAPPHSC

ENSGT00390000016737_Linker_0_1 (358, 367)

P--
--PDDK

PF15620 // ENSGT00390000016737_Domain_1 (367, 740)

KVIEDEFIIDESDQSFASRSWITIPRKAGPLKQ-RPISP-AESTALL-QNGK-S
-----------------------REKHHNILPKTLANGKHSHE-----------------
-------------------PHPVEPSQSSDKTVLDTSYALTGETENDCKSAKYEMCSKDA
EKSSGS--KRTIKQKQRR-KFKAKPAEEQLDVGQSKDENIRMSHT-TQDKFQR--NSDRN
IEE---REEIGNDC----VSKKQMS-PVGSKK--SSA------RKDKGEAK-KK------
-HFSNES--------------------KN-KLV--PEEV-ISTVTRSRRISRRPSDWWVV
KSEESPVYSNS-SIRNELP

ENSGT00390000016737_Linker_1_2 (740, 1136)

VHRNSRQKS-AKKTNQSSKNIGEKTIPLKRQKIATKGNQRV
Q-K---FLNAKGSGG---TV-GHD-EISSCLLS---EPL---------ESDEEDLAKKKN
LDCSRS--TRSSKKE--------------DNVM-TAQ-HVPLKPQTS-GYTYNT-PTESS
-------------------LDSGERKTLVLEESGPSRLNNNYLTSGKNNNDVDEEEVHGS
S--------------DDS--KRSKVIP---KNRIHHKLVLPSNTPNVRRTKRTRLKPLEY
WRGERIDYQGRPSGGFVIGGILSPDTMSSKR-KAKENIGKVDKKSNKK-RICLDNDERKT
-SLMVNLGIPLGDPLQPTRVKDPETREIIL-MDLVRPQDTYQFFVK-----HGEL

PF11699 // ENSGT00390000016737_Domain_2 (1136, 1219)

KVYKT
LDTPFFSTGKLILGPQEEKGKQHVGQDILVFYVNFGDLLCTLHETPYIISTGDSFYVPSG
NYYNIKNLLNEESVLLFTQIKR------------------------

----------------MGFGD-----------QYLSAFLFVT------------------
-----EEKKN--KPSSGNRTSHS--KKHNEKSTQKQS-----------SSKQ--------
----------------------------PHSRKAVDAEAKQGS----------------S
SK---------ENHSVSDCSD------IS--SGTSSRSQR-----------GRQS-----
-----------------------------KLPGQWWVVR----REEDRP----------S
S---PPANPGIVGKSSKN----TVLGKRKFPEVVTKTK---QADFGRVRKSILKS-ASIY
NTQAAEEEDDGREEEEED-----DDNIFSKPVQQRKLVKLDSKVR-MNMRSSI-SS----
------------FAAVFAKS-------PAIAPKGMSQESHGDM-KEVSRVTKVPRAP-SQ
SIEE-RPQPVQTGTVRKRTGAEASKSSPKKRKP---VHLEDSEA----------ES----
--VL----SQQAAEAASFNQDPEPAGVSRRTPGSELHANSGDSSS-EQN-----------
------------------------------GKRSDSKKRKKMAKQGQKSVR-KGRQPTSE
STPRTEPPAFTSSDEREEESQSGSTEQRNKKKITDKGE--EKSVKQGRTMEKGRQ----P
-------TTSEL-HLRKEPEAFTGSY--ENGERDSS------------DHKSERNDSEKR
KKTAKQGKNVKRRKQSTLELSPRK-EPPASSSSDESERGNGSDSID---RRNKKYTDKRK
GKTSKQ--SR---------TIKKGKQPMTSGLLPGRQ-STAFSSSDESGEEVQS-SRYFA
VKEKKSKRRKETKRRQELLSQPRARSHLLTLM---SSEESEEWLGEKSGPV-KAQ-----
-------------------RINLSVTDEQLMQQEESLQVLPSTTPNVWRSKRMRVRPLEY
WRGERVDYKLSPSGGLVVEGVLSPVGQQIQR-RIKLRRNAER-------RREGEGGS---
SAVQNLSGCSEVESTSPVEVWDATRSQRIL-LNCMRSGNDCLFHRGTVEENNGYLL

PF11699 // ENSGT00390000016737_Domain_2 (1137, 1201)

VYKN
LDQPEFATGRLLLGPFTEKKPQCVYEDTISFFISKGLVEVSIDQTARKLRSGDFFFVPAG
ELKIFIFY------YLFL----------------------------

----------------------------

PF15622 // ENSGT00390000016737_Domain_0 (29, 194)

HLKNDYRRRFCRPSRVPDIHTAQGQNMMDILQ
DCFEEKSVLNNFVTNSTESLLCLTPKMKDSCIQ-STHK-----EI--SHSKS----VPVS
SGRKE-A-----------SPQGIGEPSETASSSVEANEIDHKTLTT--------------
-------------

ENSGT00390000016737_Linker_0_1 (194, 366)

DDDDFYLSIGSPAVLLDSKAYES--P------------NAVSSADQM
REPYSLRNSVNMRSSRKNISFRPKKRLNFDI---STRVEIKNKKSEVENKISERQQEGPS
S---ETSEK-----RVQIQPQAKKSFSTLFLETVKRKTES--STIIRHSSTVPPLSSS--
--SND

PF15620 // ENSGT00390000016737_Domain_1 (366, 741)

MKLLEDEFIIDESEKSFASELWVTIPRKDRHLKH-HAASS--SENTAV-LLDK-S
-----------------------REKPHNVSSKTLISDTQSQK-----------------
-------------------APPVEKSQPSVEKKKRTGCALTNELENNCRSTEYEMHSENA
RKTSGS--KRTIKQKRRR-PSKANVVDEQINKGQGKNENRNMSCI-AQDKLQI--NSDRN
TEE---CEEARNGP----VSKKQMP-PVGNKEKKSGI------QKDKKKSR-KK------
-RFSSGS--------------------KN-KLV--PEEV-TLTVLRSRRISRCPSDWWVV
KPEENTFDRNS-SKGNELS-

ENSGT00390000016737_Linker_1_2 (741, 1136)

VYQNRQKN-TK-KNRLSKDTGKIPVPSKRRKTTTQSSSRV
Q-K---FLDIKDSGE---SSIHCD-EIS-SRQN---EPL---------ENDKEDLTQKKN
LDFSGT--IGCTKYQ--------------NSVK-TVC-NVHLKSHTC-ECIRKI-PKESN
-------------------LDSGKPQISGLEVSGPSRLT-NCVMSGKNNSDMEDKEPFLQ
----------------H--------LN---TFCVIFFTVLPSNTPNVRRTKRIRLKPLEY
WRGERIDYQERPSGF-VIGGIISPGSVSPKR-KAKGNLGKVNKKANNK-RICHDNHEKS-
-MNL----GQRGDPLQPTRVKDPETREIIF-MDLIRPRDTYQFFVE-----HGDL

PF11699 // ENSGT00390000016737_Domain_2 (1136, 1219)

RVFKT
LDTPFFSTGKLVLGPCEEKGRQHVGQDILVFYVSYGDILCTLHETPYMITTGDSFYVPSG
NYYNITNLLNEESILLFTQIKR------------------------

----------MASFHLDHLKNY------------HRRFCRPSRAPNIHTKKGQNMLEILQ
DCFEEQN-------FT-ESLT-LTPKEKADYSQ-SLGE-----ECPASHSKP----VPVS
SKTGE-A-----------PLQASAEPREAASGSVQANEV---------------------
---------HHG

PF15622 // ENSGT00390000016737_Domain_0 (193, 356)

-ASDESRSSIGSPVVLLGANMSAS--Q------------KAVSSAGQK
RVASVARSPVDKQASNTNISFKTRKRLNFEDKVISNTAEIENSALPVEDNISEGQ-EGTS
S---EITQK-RDDLSFEVQSRSKKSFSELYLETVKRKNKS--SSVVRHTAAVPSS

ENSGT00390000016737_Linker_0_1 (356, 367)

PPP--
--LNDI

PF15620 // ENSGT00390000016737_Domain_1 (367, 740)

KLLEDEFIIDGSDRSFSSRPWVLIPKKDRHLSP-HKPSP--ENIALL-QGKK-S
-----------------------REKPQSLSATTFVSNTQSDK-----------------
-------------------AHPVEEAQLSVDENL--GTTWTDELENDCRSTENKMHSKTA
KKPPAR--KRTTKRKQRR-VSKPKEAE-ELSVGQSNRENSSVSNT-GQDKLQI--NSKRN
MRD---CEEVRNEP----SPKKHKA-ALENKKKTNST------QTNKGKSG-KK------
-CFSGGS--------------------KN-KFV--PEEV-TVASRRERRVSQHPSDWWIV
KPDESSVDGNS-SKENDSS

ENSGT00390000016737_Linker_1_2 (740, 1136)

VVYPNKKKQ-TK-RNHVSKNTGKKSCPSKRQKT--EISSRV
Q-K---SLNVKGSGG---TVSGHD-DIS-SSQR---KPL---------KSIEADPTQ-KS
LDISGP--KRGCKYQ--------------NNVM-ISP-NVHLKSHTE-EYTSKT-QMESA
-------------------SNSEVSKRSVWEESGPSRLK-NYEMPGSSNSVLDNEKDQKS
L---------------HLKTRSSNMVP---DKKLHHKLVLPSSSPGVRRSNRIRLKPLEY
WRGERIDYQESSSGR-LVVEIVSPASASTKI-KAKRNLGKVNKKVTKK-QFQLDSCERT-
-KMKLTRDVPLGDPFQATLVKDPETRELVP-MDLIRPRDTYHFFVE-----QHGL

PF11699 // ENSGT00390000016737_Domain_2 (1136, 1219)

KVFKT
LDTTFFSTGKLVLGPYEEKGKQHVGQDILVFYVYFGDLLCTLHETPYNITTGDSFYVPSG
NHYNIKNLLNVESSLLFTQIKR------------------------

----------MASFHL

PF15622 // ENSGT00390000016737_Domain_0 (17, 192)

DHLKN------YH------RRYCRSSRAPNIHTKKGQNMLEILQ
DCFEDQSKASFLDDFT-ESLTSSTQKKKANYSQ-SSSK-----KCPESHSKP----VPVS
SRTGE-A-----------SLQASAEPSEAAGGSVQANEV---------------------
---------HHG-ASDELDLCVGSPVVLLDANVNTL--Q------------KAASPAGQK
RVASVSRSPVDRQASNKNISFKTRKRLNFEDKVTLSTAETENSVLQVEDNLSKGQ-EGTS
S---EITQK-RDDLSSDVQSRSKKNFSELFLETVKRKSKS--SSVVRHTAAVPFSPPP--
--PSD

PF15620 // ENSGT00390000016737_Domain_1 (366, 740)

MKLLEDEFIIDRSDRSFSSRLWVMIPSKDRHLSA-HKPSP--ENTALL-QGKK-S
-----------------------REKSHSLSAMTFARNTQSDK-----------------
-------------------AHPIEEAQLSVEENP--ATTCTDELENDCRSPENKMQSETA
KTPPAW--ERTTKQSQRR-VSKPKAAE-ELRKGQSSWENSNVSNT-GQDKLQI--NSKRN
MKD---CEEVRNEP----NPKKQKP-ALENKKKTNST------QTNKEKSG-KK------
-FFSGGS--------------------KN-KFV--PKKV-TLTSRRSCRISQRPSEWWRV
KSDESSVDRNP-SKENNSP

ENSGT00390000016737_Linker_1_2 (740, 1136)

VVYPNKKKQ-TK-RNHVSKRAGKKPGSSKRQKT--EMSPRV
Q-K---SLNVKDSGG---TVSGHD-DTS-RSQR---KPL---------KIIEADPTQ-KS
LAISRP--KRGCKYR--------------NNVM-TSP-NVHLKSHTE-EYTSKT-QMESA
-------------------SNSEMSKRSVWEESGPSRFK-NYEMPGSSNSEMGDEQDQKS
L---------------HFTTRSFNMVP---DKKLHHKLVLPSNSPNVRRSNRIRLKPLEY
WRGERVDYQESSSGQ-LVLEIISPSSVPTKI-KAQRNLGKVNKKVTKK-PTHLNSHEKA-
-KMELPLDMRLGDPFQATLAKDPETAELVP-MDLIRPRDTYRFFVE-----QHGL

PF11699 // ENSGT00390000016737_Domain_2 (1136, 1219)

KVFKT
LDTIYFSTGKLVLGPYEEKGKQHVGQDILVFYVNFGDLLCTLHETPYKLTTGDSFYVPSG
NHYNIKNLLNVESSLLFTQIKR------------------------

------------------

PF15622 // ENSGT00390000016737_Domain_0 (19, 216)

LKNY------------HRRFCRPSRAPNIQAKQGQNVLDILQ
DCFEEQSKASFLDGLSELSLRCSTPKVKDNHNQ-SAGK-----ECQASCSKS----VLGS
SRSKE-A-----------FLQVAAELSEAAHGSVQANEVHPKIPAT-DV-SKSTADSNN-
------------------------------MSTSE

ENSGT00390000016737_Linker_0_1 (216, 366)

L--Q------------NVISSLSQK
RVASVLRNSGDTKSSNTDISLKTRKRLNFEDKSILNKAEIENNVLEEDS-TSEVQ-EGIA
S---ET-SQRRQDLSNEIQPRSKKSFSALYLETVKRKSES--SSIVRHTTAVRPLSSP--
--PND

PF15620 // ENSGT00390000016737_Domain_1 (366, 739)

MKLLEDEFIIDESDRSFASQPWVTIPRKSRPLRQ-HLPSP--ENIGTP-KDKK-S
-----------------------REKPHSVSAKTLISGSQSHK-----------------
-------------------APPKEKSQPSVENLL--GISRTDELENDCRSTENKMHSENA
KEPSGS--KRTVRQQQRR-ASKPTIVEEQVNVQKGRKGKRNMPNT-GRDKSHV--NSERN
MED---CEEVRNEP----VPKKQML-PVENKKKKHST------QKDKEKSR-EK------
-CVSGGS--------------------KD-KCV--PDEV-SLSVRRSCRISHHPSEWWLV
KPEEGSVNRSS-SRENES

ENSGT00390000016737_Linker_1_2 (739, 1136)

SGVDHNRRKR-AK-KNQLPANPGKKPFPSKRQKT--ESSSRV
Q-K---SSNVKGSRG---SV-SHD-EIS-GSQS---EPL---------ENNEADPTQMKS
LDISGP--TRGSKYQ--------------NSIM-TSQ-NVRLKSHTG-KYTSKT-PIESI
-------------------SDSGEPKNSIWEESGPSRFK-DHLMSGSSNSDVGGE--KES
L---------------DLRIRSSNVPP---DGNIHHKFVLPSRSPNVRRTKRIRLKPLEY
WRGERIDYQERPSGR-IVIGILSPPPVSPRR-KSKRNLAKVTKKANRK-R----------
--IHLNLDITLGDPFQATLAKDPETREIVP-MDLIRPRDTYQFFME-----QHGL

PF11699 // ENSGT00390000016737_Domain_2 (1136, 1219)

QVFKT
MDTAVFSTGKLVLGPHEEKGKQHVGQDILIFYVNFGDLLCTLHETPYMITTGDSFYVPSG
NHYNIKNLLDVESCLLFTQIKR------------------------

----------MAVSG---------------------------------------LDHLK

PF15622 // ENSGT00390000016737_Domain_0 (60, 325)

N
DCFEEKSLANDFSTNSTKSVLNSTSKIKDTCIQ-SPSK-----ECQKSHPKS----VPLS
SRKKE-A-----------SLQFVVEPSEATNRSVQAHEVRQKILAT-DVSSKNTPDSKKM
SS--RNINDHHSEADEEFYLSVGSPSVLLDAKTSVS--Q------------NVIPSSAQK
RETYTFENSVNMLPST--------------------------------------------
----------------------KK

ENSGT00390000016737_Linker_0_1 (325, 366)

IFSTLFLETVKPKSES--SPIVRQGGIAPPHSCP--
--PDD

PF15620 // ENSGT00390000016737_Domain_1 (366, 739)

MKLIEDEFIIDESDQSFA-----------GPLKQ-RTISP-AESTALL-QDRK-S
-----------------------REKHHNILAKTLANDKHSHK-----------------
-------------------PHLVETSQPSDKTVLDTSYALTGETENDCRSTKYEMYSKNA
EKSSRS--KRTIKQKQRR-KFMAKPAEEQLDVGQTKDENIHMSHI-TQDKFQR--NSDRN
MEE---REEMGNDC----ASKKQMP-PVGSKK--SST------RKDKEESK-KK------
-RFSSES--------------------KN-KLV--SEEV-TSTVTRSRRISRHPSNWWVV
KSEESPVYSNS-SIRNEL

ENSGT00390000016737_Linker_1_2 (739, 1136)

PLHHNSRQKS-AKKTNQSSKNIGKKTIPLKRQKTATKDSQRV
Q-K---FLNAKGSGG---II-GHD-EISSCLLS---EPL---------ESDEADLAKRKN
LDCSRS--TGSSKNE--------------DNIM-TAQNNVALKPQTS-GYTCNT-PTESN
-------------------LDSGEHKTSVLEESGPSRLNNNYLMSGKNNNDVDDEEVPGS
S--------------DDS--KRSKVIP---KNRIHHKLVLPSNTPNVRRTKRTRLKPLEY
WRGQQIDYQGRPSGGFVISGILSPGKISSKR-KARENIG-------KK-RICLDNDERKT
-SLMVNLGIPLGDPLQPAVVKDPETRELIL-MDLVRPQDTYQFFVK-----HGEL

PF11699 // ENSGT00390000016737_Domain_2 (1136, 1219)

KVYNT
LGTPFFSTGRLILRPQEEKGKQHVGQDILFFYVNFGDLLCTLHEIPYIISTVDSFYVPSG
NYYNIKNLLNEESVLLFTQIKR------------------------

----------MAASGL

PF15622 // ENSGT00390000016737_Domain_0 (17, 358)

DHLKN-----------GYRRRFCRPSRARDINTEQGQNVLEILQ
DCFEEKSLANDFSTNSTKSVPNSTRKIKDTCIQ-SPSK-----ECQKSHPKS----VPVS
SKKKE-A-----------SLQFVVEPSEATNRSVQAHEVHQKILAT-DVSSKNTPDSKKM
SS--RNINDHHSEADEEFYLSVGSPFVLLDAKTSVS--Q------------NVIPSSAQK
RETYTFENSVNMLPSSTEVSVKTKKRLNFDDKVMLKKIEIDNKVSDEEDKTSEG-QERKP
S---GSSQNRIRDSEYEIQRQAKKSFSTLFLETVKRKSES--SPIVRHAATAPPHSC

ENSGT00390000016737_Linker_0_1 (358, 366)

P--
--PDD

PF15620 // ENSGT00390000016737_Domain_1 (366, 739)

TKLIEDEFIIDELDQSFASRSWITIPRKAGSLKQ-RTISP-AESTALL-QGRK-S
-----------------------REKHHNILPKTLANDKHSHK-----------------
-------------------PHPVETSQPSDKTVLDTSYALIGETVNNYRSTKYEMYSKNA
EKPSRS--KRTIKQKQRR-KFMAKPAEEQLDVGQSKDENIHTSRI-TQDEFQR--NSDRN
MEE---PEEMGNDC----VSKKQMP-PVGSKK--SST------RKDKEESK-KK------
-RFSSES--------------------KN-KLV--PEEV-TSTVTKSRRISRRPSDWWVV
KSEESPVYSNS-SVRNEL

ENSGT00390000016737_Linker_1_2 (739, 1136)

PMYHNSSQKS-TKKTNQSSKNIRKKTIPLKRQKTATKGNQRV
Q-K---FLNAEGSGG---IV-GHD-EISRCSLS---EPL---------ESDEADLAKKKN
LDCSRS--TRSSKNE--------------DNIM-TAQ-NVPLKPQTS-GYTCNI-PTESN
-------------------LDSGEHKTSVLEESGPSRLNNNYLISGKN--DVDDEEVHGS
S--------------DDS--KQSKVIP---KNRIHHKLVLPSNTPNVRRTKRTRLKPLEY
WRGERIDYQGRPSGGFVISGVLSPDTISSKR-KAKENTGKVNKKSNKK-RICLDNDERKT
-NLMVNLGIPLGDPLQPTRVKDPETREIIL-MDLVRPQDTYQFFVK-----HGEL

PF11699 // ENSGT00390000016737_Domain_2 (1136, 1219)

KVYKT
LDTPFFSTGKLILGPQEEKGKQHVGQDILVFYVNFGDLLCTLHETPYILSTGDSFYVPSG
NYYNIKNLRNEESVLLFTQIKR------------------------

------------------------------------------------------------
-----MTTEGDFADLPG-YLISVRSKARVYCKSYKTVLK---KKCQKSLTNS----MPVS
SRKNE-A-----------CLPLIVEPSEAANKSVQAHEVHEKILAT-DVDSKNTPVLKNV
SS--RKLNGHRSEADGEFYLSVGSPSVILDAKTSLS--Q------------NAIPSVAQN
RETYTLEKSVNTLSPSTEISVKPKKRLSFEDKDILKKVDIADKVSENEDKVSEGPQKRKP
S---GTSHERTEDTEYEIQPQAKKSFSTMFLETVKRKSES--SSLVRHVVPAVPHSSS--
--PNDVKLLEDEFIIDESDRSFASPSWITIPRKTGPSKQ-CTRSP-VESTVLF-QGKK-L
-----------------------REKHHNITSETLTSDKHSHK-----------------
-------------------AQPIQRSEPSGQKKLGRNCASTDEMENNNRSIKYALYSENA
EKSSEN--KSTVKQKQ-R-KLKATVVEEQLDLEQSKVKNINMSQK-SQDKFQR--NSNRN
MEE---FEEIRKDH----VSKKQM--PVGKKKSSTSVSHKKHKKKDKEELK-NK------
-HSSNGP--------------------KKNKLI--PDEV-PLTIRRSRRISRCPSNWWEV
KPEKSPVCSSSS-IRNELSVHHNSGQKS-AKKKNQSSKNIREKTLPLKRQKRATQGSSST
QKK---FLNAEDSGG---IT-GHN-EISRCFQN---KSL---------ENDKIDLAKKKN
LDHSGV--ARSTQDP-----------DCSDGIE-TAQ-NVHVKSQ----DTCKT-PVESN
-------------------VDSKEPETSVLEESGPSRLQ-NYLVSGKNNSDTDEKDVQES
S--------------DNSRIKSSK-VT---ENKIHHKLVLPSHTPNVRRTKRMRLKPLEY
WRGERIDYQGRPSGGFVIGGILSPDMISSKR-KAKGNKKKVNKIANRK-RICLDNDERKR
-KLMTDLNIRLGDPFQPTEVKDPDTREIIL-MNLVRPRDTYQFFVE-----YDEL

PF11699 // ENSGT00390000016737_Domain_2 (1136, 1219)

KVFKT
LDTSYFSTGKLILGPCQEKGKQHVGPDTLVFYVDFGELLCTLHETPYVITTGDTFYVPSG
NYYNIKNLLNEESILLFTQIKR------------------------

----------MAATGL

PF15622 // ENSGT00390000016737_Domain_0 (17, 358)

DHLKN-----------DYRRRFCRPSRAPDINTKQGQNILEILQ
DCFEEKSLTNDFSTNSTKSVLYSTPKMEDICIQ-SSSKE---AQCQKSHPKS----VPVS
SRKKE-A-----------SRQFTVEPREVVNRSVQDHEVHQQILAT-DVGSKNTPDSRKM
SS--EKLKRHHGGVDEEFYLSVGSPFVLLDAKTCVS--Q------------SAVSSIAQN
RKTYTSEKSVNTLSSSTEISLKTRKRLNFEDKNISKKVEIPNELSETEDKVSEEPQERKS
S---RTSQKRVQDSEYEVQPQTKKSFSALFLETVKRKSES--SPVVRHIATAPPHSS

ENSGT00390000016737_Linker_0_1 (358, 366)

P--
--SND

PF15620 // ENSGT00390000016737_Domain_1 (366, 740)

LKLLEDEFIIDESERSFASTSWITIPRRAGPLKQ-CTVTP-AENTALL-QSKK-S
-----------------------KEKHHSVSTADLTSDERSGK-----------------
-------------------AHPVGRSQPSEQKGVNKGCALSNEMENHCRSTKYELYYENA
EKSSGN--RRTVRQKQRR-KFKANVLEEQVDTEQSKDKNTNMSHI-TQDKLQR--NSDRN
MEE---CENTINVA----ISKKQVL-PVGRKKNSTSVPYTENQKKAKE-YK-KK------
-QFSSGS--------------------KKNKLV--PDEV-TSTITRSRRISRRPSNWWVV
KSEQSLVYSKSS-RRNELS

ENSGT00390000016737_Linker_1_2 (740, 1136)

VCHNSRQTP-VEKPNQSSKNIGDKTIPFKGQKRTTSGSSRT
Q-E---FLTAKDSRR---II-DHD-KISGSSQN---ESL---------KSDEEDLVKKKN
HDHSGG--TRSPKDQ--------------DS-M-TAQ-NVHPKSQVK-GFTCKT-LAESN
-------------------LDSGEPKTSVLERSGPFRLK-NYLSSEKSNSDVDDKEFQES
S--------------GDSGVKISRVLS---VNKIHHKLVLPSNTPDVRRTKRTRLKPLEY
WRGERIDYHGRPSGGFVIGGILSPDTVSSKR-KAKGNIGKVNKLVNRK-RICLDNDERKN
-KFMLNLNVPLGDPLQPTRVKDPETREVIL-MDLLRPRDTYQFFVE-----HGEL

PF11699 // ENSGT00390000016737_Domain_2 (1136, 1219)

KVYKT
LDTPIFSMGKLILGPHQEKGKQHVGSDILVFYVNFGDLLCTLHETPYIITTGDSFYVPSG
NYYNIKNLLNEESILLFTQIKR------------------------

----------XXXXXXN

PF15622 // ENSGT00390000016737_Domain_0 (18, 358)

HLKN-----------GYRRRFCRPSRAPDINTEQGQNILEILQ
DCFEEKSLANDFSTNSTKSMVYSTPQIKDICIQ-SPSK-----ECQKSQSNS----VPVS
SKKKEAA-----------SLQFVVEPSAKAASRSVQACEIQKILEI-DVGSKNKPDSKEE
PS--KKLSVHHREAEQEFYLSVGSPSVLLDAKTSIS--Q------------NVLPPIAQE
REAYTFGNSVNMLSSSMQSSLKTKKRLNFEDKVILGKVEIENEVSEEEDNISEGQQERKL
S---GTSQKRMQDSEYEIRPQARKSFSTLFLETVKRKGES--SPIVRHTAAAPLNSS

ENSGT00390000016737_Linker_0_1 (358, 366)

P--
--SSN

PF15620 // ENSGT00390000016737_Domain_1 (366, 740)

MKSIEDEFVIDESDRSFSSRSWIAIPRKTGHVKQ-HTVSS-AESTALL-QDKK-S
-----------------------QEKHHHASPKTLASDTHSRK-----------------
-------------------PHPVEKSQPSDKNKLSTSCALTDEVEDDCRATKYKMYSDNA
AKLSGS--KRTVKQNQRR-KFKTNVVEKQLSVGQSKGENTNMSHI-TQDTFQR--NLDRN
MEE---GKELRNDT----IANKQMP-SVGSKK--GST------RKGKEELK-KK------
-CFSSES--------------------KKNKFV--PEEV-TSTITRSRRISRRPSNWWVV
KSEESHVYNGSSQIRNESS

ENSGT00390000016737_Linker_1_2 (740, 1136)

VHLNSRQKP-AKKTNQSSKIIGQKKIPVKRQKAATQGSSRL
Q-K---FSSAKGSED---AI-GQG-KISSCSQN---EPL---------QSDKADLTKKKN
LDCSRS--TGSSEHQ--------------DGTM-TAQ-NVNPKTTTS----GRI-PTESK
-------------------LYSEESKTSMLEESGPSRLN-NYILSGKNNSDVEDEEILES
S--------------DDS--KRSNVIP---KNRMHHKLVLPSNTPNVRRTKRIRLKPLEY
WRGERIDYQETPSGGYVIGGILSPDTVLPKR-KAKENIEKVK---KGK-KICLDNDERKT
-RLIVNLDIPLGDPLQPSRVKDPETKEIIL-MDLIRPRDTYQFFVK-----HGEL

PF11699 // ENSGT00390000016737_Domain_2 (1136, 1219)

KVYKS
LDTPLFSTGKLILGPHQEKGKQHVGRDILVFFVNFGDLLCTLHETPYIITTGDFFYVPSG
NYYNIKNLLNEESVLLFTQIKR------------------------

----------MAASGL

PF15622 // ENSGT00390000016737_Domain_0 (17, 326)

DHLRN-----------GYRRRFCRPSRARDINTEQGQNVLEVLQ
GCFEEKSLANDFSTNSTKSVLNSTCKIKDTCMQ-SPSK-----ECQKPHPKS----VPLK
N-------------------PFLAKPSEATNRSFVR-----KFLAL-MLVVQKYTDSKKM
SS--RNINDHHSEADEEFYLSVGSLSVLLDAKTSVL--Q------------NVIPSSAQK
RETYTFENSVNMLPSSTEVSLKTK------------------------------------
-----------------------KS

ENSGT00390000016737_Linker_0_1 (326, 368)

FSTLFLET---------------------------
-------

PF15620 // ENSGT00390000016737_Domain_1 (368, 740)

LIEDEFIIDEPDQSFASRSWITIPRKAGPLKQ-STISP-AESTALL-QDRK-S
-----------------------REKYHNILAKTLANDKHFHK-----------------
-------------------PHLVETSQPSDKTVLDTSYALTGETENDCRSTKYEMYSKNA
EKSSRS--KRTIKQNQRR-KFMAKPADEQLDVGQSKDENIH-----------T--NSDRN
MEE---REEMGNDC----ASKKQMP-PVGSKK--SST------RKDKEESK-KQ------
-HFSRES--------------------KN-KLV--PEEV-TSTVTRSRRISRHPSNWWVV
KSEESPVYSNS-SIRNALPVHHTSRQKS-AKKTNQSSKNIGKKTIPLKRQKTATKDSQRV
Q-K---FLNAKGSGG---II-GHD-EISSCSLS---EPL---------ESDEADLAKKKN
LDCSRS--TGSSKNE--------------DNII-TAQ-NVPLKPQTS-GYTCNT-PTESN
-------------------LDSGEHKASVLEQSGPSRLNNNYLMSGKNNNDVDDEEVHGS
S--------------DDS--KRSKVRP---GNRIHHKLVLPSNTPNVRRTKRTRLKPLEY
WQGEQIDYQGRPSGGFVINKI------SSKR-KARENIG------------------KKT
-SLMANLGIPLGDPLQPTREKDPETREIIL-MDLVRPQDTYQFFVK-----HGELKVCKT
LDTSFFSTGKLILGPQEEKGKH----------------------------TGDSFYVPSG
NYYNIKNLLNEESVLLFTQIKR------------------------

----------MAAWGL

PF15622 // ENSGT00390000016737_Domain_0 (17, 358)

DHLKN-----------GYRRRFCRPSRAPDINTEPNQNILEILL
DCFEEKSLPSDFSTNSTKSGLNSTPKIKDNYIQ-SPREE---IQCQ-KAPES----DPVS
SKKKQ-A-----------SMQLIVEPGEAVNTSVQAHEVHHKILAP-EVHSEHTSDLRKM
SG--KKLKDHHKEADEEFYLSIGSPSD-LDAKATLL--Q------------KAVPSVAQK
RETYTSENSVNTMSSSTESSRKTKKRLNFGDKDVLKKVEIVNNTSEIGDKVSEGPQEKKQ
S---GTSEKRIQGSEYEDQPQTRKSFSTLFLETVKRKNES--SSVVRHT-TAPPHLS

ENSGT00390000016737_Linker_0_1 (358, 366)

P--
--TNN

PF15620 // ENSGT00390000016737_Domain_1 (366, 740)

TKLLEDEFIIDESDKSFANQSWITIPRKSGPLIH-GTVSP-AEST-AL-QRKK-S
-----------------------REKCDSVSSTALTSDKHSSK-----------------
-------------------AHPVEKSQPFEQNILGGSCASTDEMENNCKSAKYEMYSENG
KKSSGN--KRTIKQKQGT-QFKANVVEEQVDMEHTKDKNINISHI-AQDKLQR--NSGQN
MEE---REEI-GVQ----ISKKEMP-PMGSKRGSTNIPYTMNKKKDKE-CK-RK------
-CFSDGS--------------------KKNRIL--PEEL-TSTVTRSRRISRCPSDWWVV
KSEQSLFYSNSS-TRNELS

ENSGT00390000016737_Linker_1_2 (740, 1136)

VNHNSKQKP-AEKTNQSSKNIGKKTIPFKRQKKTTEGSSRA
Q-K---VLNAKDAGE---II-DRE-EIFSCFRN---ESL---------EGNEAVQAKKKN
HNPSGD--TGGTKDQ--------------DS-V-VAQ-NVPLKSQIS-RYMCKT-PAESN
-------------------LDSGEPETSVLEESGPSRLK-NCLTSGKNNSDVDDNEVQQS
S--------------DDPRVERCNSTP---ENKMHHKLVLPSNTPNVRRTTRTRSKPLEY
WRGERINYQGRPSGGFVVGGILSPDTVSCKR-KTKGNLGKVNTAVNRK-RICLDNDERKN
-KLMVNLNVPLGDPLQPTRVKDPETREIIL-MDLVRPRDTYQFCVE-----HGEL

PF11699 // ENSGT00390000016737_Domain_2 (1136, 1219)

KVYKT
LDTPFFSTGKLILGPLQEKGKQHVGLDTLVFYVNFGDLLCTLHETPYIITTGDTFYVPSG
NYYNIKNLLNEESILLFTQIKS------------------------

----------MAASGL

PF15622 // ENSGT00390000016737_Domain_0 (17, 358)

DHLKN-----------DYRRRFCRPSRVPDINTNQNQNMLEILQ
NCFEEKSLFDDIITNSTKSVLYSTPKMKNSCTE-SSGK-----DCQKSHPRS----FPVS
SREKE-A-----------SLQGIVEPNEAASESVQAHEIYQKVLAA-DVCSKRTPDLTKN
SG--KKLNVLCAEADEEFYISVGSPAVPLHEKPSKS--Q------------NDIS-SAQK
RETYTFGNSVNMLSSRTEISLKTKKRLNFEDKDILKKVERETNKSEVEDKISGQ-EERKL
S---ETSPKRVQDTEYEIQSQTKKSFSTLFLETVKRKGEP--SPIVRHTASAPSHSS

ENSGT00390000016737_Linker_0_1 (358, 366)

P--
--PNV

PF15620 // ENSGT00390000016737_Domain_1 (366, 740)

TKLLEDEFIIDESDRSFVSQSWITIPRKSRPLKQ-HTISS-VESTAVL-QCKK-A
-----------------------RE-HESVLPVTLTNDKHLHK-----------------
-------------------THPEEKSEPPNEKKPSTSCTLIDELENS----------EKA
EKPSGN--KRTTKQKQKR-KLKTIVVEEQLDTGQSNDEN--MSHI-AHDKLPG--NSNRT
IEG---CGEMRNGH----NAKKEMP-PVEHMKTKCST------KKDKKESR-KK------
-HFSSES--------------------KRKKIV--PEEI-TSTVTRSHRISRRPSDWWVV
NAEESPVHSNS--VKNDVS

ENSGT00390000016737_Linker_1_2 (740, 1136)

VYHSTRQEP-AKKTNQSSKKIVKKTILSKRQKASTQGNSRV
Q-K---LLNVKGSRS---IF-DLD-EVSSCPQN---EPL---------ENAQIDLIKKKN
LDCS--RTTGLSKDQ--------------DVIM-STE-NVHLKSPTS-EDTCRT-PVEAP
-------------------VDSGESETSVLEESGPSRLK-NYLISGKNNSDVNNA-VQEN
LAASKAHCYEKVFNKDDLRVKRYKVAS---RNEMHHKLVLPSNTPNVRRTKRIRSKPLEY
WRGERVDYQETPSGGLVIGGILSPETVISKR-KAKGNVGKDNKIDNRK-RICLDNVEKKS
-KLVVNLGIPLGDPFQPTQVKDPETREIIF-MDLIRPRDTYQFFVE-----HGKL

PF11699 // ENSGT00390000016737_Domain_2 (1136, 1219)

KVYKT
LDTPLFSTGKLILGPYEEKGKQHVGEDILVFYVNVGDLLCTLHETPYAITTGDSFYVPSG
NYYNIKNLLNEESILLFTQIKR------------------------

---------------L

PF15622 // ENSGT00390000016737_Domain_0 (17, 150)

DHLKNY------------HRRFCRPSRAPNINTRQGQNVLEILQ
DCFEEQSKASFLDELSELSLLCTTPKAKDNCTQ-SAGK-----ECQVSHSKS----VRVS
SRRKD-A-----------SLKVAAEPSEVACGSG--------------------------
-C--EKTNAHHRATNDNFYLSGGSPVVLLDARTTEL--Q------------NGTSSLGQR
RVSSNVRNSVDTKSSNTDISLKTRKRLNFEDKSILNQAEIVNNALEVEDNILEGQ-ERTT
S---ETSQKRGQDLSYEIQRRSKKSFSTLYLEAVKRKSES--SIV-RHTAAVPPLSSP--
--PND

PF15620 // ENSGT00390000016737_Domain_1 (366, 740)

MKLLEDEFVIDESDRSFASQPWVTIPRKGRHLRH-HVPSP--ENTVTP-EDKK-S
-----------------------REKPHSVSPTTSISDSQPQK-----------------
-------------------SPPIGKSQPPVENIL--GTSCTDELENDCRSTENKMHSENA
KKTSGR--KRTVRQKQRR-VSKPNVVEEQLNMGQGKKGKRNMSNI-GQDKLQV--NSKRI
KKD---CEDSRKEP----TPKKQMP-PIENKKNQHNI------PQNKEKSG-KK------
-YFSGRS--------------------RN-KFV--PEEV-SVSVKR-RRVSQPPSEWWLV
KPEKGSVDRSS-SRENESS

ENSGT00390000016737_Linker_1_2 (740, 1136)

VVYHNRKKQ-TK-KNQLSKNAGKKPLPSKRQKT--ESSSRV
Q-K---SLNVKGSRE---SVSSHD-EIS-GTQS---KPL---------ENNKADKTPKKS
LDISGP--TGGSKHH--------------GSIR-TSQ-NVHLKSHTG-KYTNKR-SMESN
-------------------SGSGEHKNSIWEERCVYS--------------VVRLEVTHY
T---------------NLRISAYNVLP---DRNIHHKLVLPSSSPNVRRTKRIRLKPLEY
WRGERIDYQERPSGR-IVIGIVSPAVVSPKK-KAKGNLGKVTKKPDKK-WICPDNHE---
---MVNLDIPLGDPFQATLAMDPETREIVP-MDLIRPRDTYQFFVE-----QHGL

PF11699 // ENSGT00390000016737_Domain_2 (1136, 1219)

KVFKT
LDTAVFSTGKLILGPHEEKGKQHVGQDVLVFYVNFGELLCTLHETPYMITTGDSFYVPSG
NHYNIKNLLNVESCLLFTQIKR------------------------

---------FGNRGCEDHLKN-----------DYRRRFCRPSRAPDINTEQGQNILEVLL
DCFEEKSLASDVSKNATKSVLYLTPKTKDICVQ-SSSKE---TQSPKSHPKS----GPVS
SRKKE-A-----------PLQLTVELNEAVSKSVQDCEVHQKILAT-DVHSKNTSDLRKM
SS--KKLKDNHSEADEDCYLSVGSPSD-LDIKASSL--Q------------KGSPSVAQK
RETHTSKNSVNMLSSSTEISHKTRKRLSFEDKDVLKKVEITNEVSEIEDKVSEGLQDRKQ
S---RTSQKRIQDSEYENQPQARKSFSTLFLETVKRKSES--SSVVRHIATVPPHLSP--
--ANNTKLLEDEFIIDESDQSFVSQPWITIPRKTGPLKQ-HTASP-AEST-VL-QRKK-S
-----------------------RERHDSVSSVALTSNKHPGK-----------------
-------------------AHPVEKSQPSEPKIPGGSCALSDDVENNCKSTKYEIYSENA
KKSSGD--KRTIKQKQRT-KSEANVPEEEVNVRQSKDKNINISHT-VQDKLQR--NSDRN
MEE---DEEI-NVS----ISKNQLL-SVGSKKGSTNVPHKKNQKKDKE-CK-KK------
-HFSSGS--------------------KNNKIE--PEEL-TSTIRRSQRISRCPSDWWVV
KSEQSSFSSSSS-VRNELSVYHNSRQKPPAEKTNQSSKNIGKKAAPFKKQKRANKGSSGA
Q-----VLYAKDSGG---A------------QN---ESL---------RSNEAELAKKKN
PNPSGD--TGSSKNQ--------------DS-M-AAQ-NVHQKSQMS-VYTCTT-PTKSN
-------------------LDSGEPGTSVLEGSGPVRLK-NYLTSGKNNSDVDDNVVQQF
T--------------DDSRGEISDSTP---ESKMHHKLVLPSYTPNVRRTMRTRSKPLEY
WRGERIDYQARPSGGFVIGGILSPDTVSSKR-KAKGNLGRIITTANRK-RICLENEERKN
-KFMVNLNIPLGDPLQPTRVKDPETQETVL-MDLIRPRDTYQFCVE-----HDEL

PF11699 // ENSGT00390000016737_Domain_2 (1136, 1219)

KVYKT
LDTPFFSSGKLIIGPLQEKGKQHVGLDTLVFYVNLGYLLCTLHETPYIVTTGDSFYVPSG
NYYNIKNLLNEESVLLFTQIKS------------------------

----------MAKSGL

PF15622 // ENSGT00390000016737_Domain_0 (17, 357)

DHLKN-----------GYRRRFCRPFRVPDINTGQGKNMLEILQ
DCFEEKSLTNDFSINSTKSVRYSTPRVKDNSIH-SSSK-------EKSHSKS----VPVS
SRKKE-A-----------PLQDIIEPNETAHKSVQGHEVLQKILAT-DIVSRNTPDLKKK
SS--KKPSDHPSEAEEEFYLSVGSPAVLLDAKTSVS--Q------------NTSSSLAQK
RETYTFGNSLNMLSSSTEISLKTKKRLNFEDKDIFKKVEIENKVSEVENKIPEGQQERKP
S---ETFQKSVQDLEHEIQPQTKKSFSTLFLETVRRKSEF--SPIVKHIVTAPPHS

ENSGT00390000016737_Linker_0_1 (357, 366)

SS--
--PND

PF15620 // ENSGT00390000016737_Domain_1 (366, 740)

MKLLEDEFVIDESDKSFASGSWITIPRKGGSLKQ-PTISP-DESTAVL-QGKK-S
-----------------------REKHRSVSPNTLRSDQHLHK-----------------
-------------------AHPEQKFQPCDEKKVDTSSSLTDELENNDRSTKYEISSENV
KKPSEN--KRPIKQNQRR-KFKANVVKEQLDLEQSKDKNVNMSHS-AEDKLQK--NLHRN
GED---CEGTRNDN----IFKTPTL-PVGDKKINRGT------KNNKEESR-KK------
-HFSSES--------------------KKNKLV--PEEV-TITVMRSHRLSRRPSDWWVV
KSDESPVHSNS-SIKNELS

ENSGT00390000016737_Linker_1_2 (740, 1136)

VYHNPRQKS-AKKTNQSSKNTGKKAIPLKKQKTAMQGSSRV
Q-K---FLNVKGSEY---IS-NHE-KLPSCSQN---EPS---------ESDKADLAAKKS
LDCSGT--TERSKDQ--------------CGVT-TAQ-NVRLKSQTS-DHICKT-PTESN
-------------------LDSGKCKTSVLEESGPSRIK-NYLMFGKNTSDVCDEEVQER
L--------------DDSRLKRTKVSP---EKKTHHKLILPSNTPNVRRTKRIRFKPLEY
WRGERIDYQETSSGEFVIGGILSPVTITSKR-KAKGNVERVKKVTNRK-RMCLDNDERKN
-KLILNVDISLRDPLQPTPVKDPETREIVL-MDLIKPQDTYQFFVE-----HGGL

PF11699 // ENSGT00390000016737_Domain_2 (1136, 1219)

KVYKT
LDTPLFSTGKLILGPYEEKGKQHVSQDILIFYVHFGDLLCTLCESSYLITTGDSFYVPSG
NYYNIKNLLNDESVLLFTQIKR------------------------

----------MAASGL

PF15622 // ENSGT00390000016737_Domain_0 (17, 358)

DHLKN-----------DYRRRFCRPSRARDINTEQGQNVLEILQ
DCFEEKSLANDFSTDSIKSVLYSTPKIKDTCIQ-SPSK-----E--KSHPKS----VPVS
SRQKE-A-----------SLRFIVEPSEVTNRSVQAHEVHQRFLAT-DVSSKNTSDSKKM
SS--RNINDHHSEADEEFYLSVGSPSVLLDAKTSVS--Q------------NLISSSAQK
RETYTFENSVNMPPSSTEISLKTKKRLNFEDKVILRKIEIDNKVSDEVDKTSEG-QERQP
S---GSSQNRMQDSEYEIQPQA-KSFSTLFLETIKRKSES--SPIVRHATTAVPHSC

ENSGT00390000016737_Linker_0_1 (358, 367)

P--
--PDDK

PF15620 // ENSGT00390000016737_Domain_1 (367, 740)

ELIEDEFIIDESDKSFASRSWITIPRKTGPLKQ-RITSPPAESTTLH-QGRK-S
-----------------------REKHHNISPKTLTNDKHSHK-----------------
-------------------PHSVETSQPSDKTVLDTSNALTGEMVNNCRSTKYEMYSENA
KKSSGS--KRTIKQKQGR-KFKAKLAKEQLDMGQSKDENMYTSHI-TQDKFQR--NSDRN
MEQ---CEEMGNDR----ASKKQMS-PLGSKK--SST------RKDKEESK-KR------
-HLSSES--------------------KD-KLV--PEEV-TSTVTRSRRISRRPSNWWVV
KSEESPVYSNS-SIRNELT

ENSGT00390000016737_Linker_1_2 (740, 1136)

VHHDSRQKS-AKKTNQSSKNIGKKTTPLKRQRTAPKGSPRV
Q-K---VLNAKGSGG---IV-GHD-EISSCSQS---EPL---------ESDEADLAKKKN
LDCSRS--TGSSKNQ--------------DDIM-TTQ-NVPLMPQTY-GYTCKT-PTESN
-------------------LDSGEHKTSILEESGPSTLK-NYLMSGKKNNDVDDEKVHGS
L--------------DDSRVKQSKVIP---KNRIHHKLILPSNTPNVRRTKRIRLKPLEY
WRGERIDYQGRPSGGFVVSGILSPDTVPSKR-KAKENTGKVDKRANKK-RICLDNNERKT
-SLKVNLDIPLGDPLQPTRVKDPETREIIL-MDLIKPRDTYQFFVK-----HGEL

PF11699 // ENSGT00390000016737_Domain_2 (1136, 1219)

KVYKT
LDTPYFSTGKLILGPQEEKGKQHVGQDILVFYVNFGDLLCTLHETPYIISTGDSFYVPSG
NYYNIKNLLNEESVLLFTQIKR------------------------

----------MAASGLN

PF15622 // ENSGT00390000016737_Domain_0 (18, 358)

HLKN-----------DYRRRFCRPSRARDINTEQGQNVLEILQ
DCFEEKSLANDFSTNSMKSALYSTPKIKDTCIQ-SPSK-----ECQKSHPKS----VPVS
SRKKE-A-----------SLQFIVEPSEVTSRSAQAHEVHQKILAT-DISSKNTSDSKKT
SS--RNINDHHSEADDEFYLSVGSPSVLLDAKTSVS--Q------------NVISSSAQK
RETYTFENSVNTLPSSTEISLKTKKRLNFEDKVILRKIEIDNKVSDEEDKTSER-QERQP
L---GSSQNKMQDSEYEIQPQA-KSFSTLFLETIKRKSEY--SPIVRHATTALPHSC

ENSGT00390000016737_Linker_0_1 (358, 367)

P--
--PDDK

PF15620 // ENSGT00390000016737_Domain_1 (367, 740)

ELIEDEFIIDESDKSFASRSWITIPRKPRPLKQ-RITSP-AESTTVL-QGRK-S
-----------------------REKHHNMSPKTLTNDKHSHK-----------------
-------------------THSVETSQPSDKTVLDTSNALTGEIVNDCRSTKYEMYSENA
KKSSGS--KRTIKQKQRR-KFKAKLAKEQLDMGQSKDENMYTSHI-TQDKFQR--NSDRN
MEE---CEEMGNDR----ASKKQMS-PLRSKK--SST------RKDKEESK-KR------
-HLSSES--------------------KD-KLI--PEEV-TSTVRRSRRISRRPSNWWVV
KSEESRVYSNS-SIRNELT

ENSGT00390000016737_Linker_1_2 (740, 1136)

VHHDSRQKS-AKKTNKSSKNIRKNTTPLKRQKTATKGSPRV
Q-K---VLNAKCSGG---IV-DHD-EIPSCSQS---EPL---------ETGEADLAKKKN
LDCSRS--TGSSKNQ--------------GDIM-TVQ-NVPLKPQTY-GYTCKT-PTESN
-------------------LDSEEHKTSILEESGPSTLK-NYLMSAKKNNGVDDEKVHGS
L--------------GDSRVKRSKVIP---KNRIHHKLVLPSNTPNVRRTKRIRLKPLEY
WRGERIDYQGRPSGGFVVSGILSPDTVPSKR-KAKENIGKVGKRANKK-RICLDNDERKT
-SLMVNLDIPLGDPLQPTRVKDPETREIIL-LDLIRPQDTYQFFVK-----HGEL

PF11699 // ENSGT00390000016737_Domain_2 (1136, 1219)

KVYKT
LDTPFFSTGKLILGPQEEKGKQHVGQDILVFYVNFGDLLCTLHETPYIISTGDSFYVPSG
NYYNIKNLLNEESVLLFTQIKR------------------------

----------MASFHL

PF15622 // ENSGT00390000016737_Domain_0 (17, 358)

DHLKNY------------HRRFCRPSRAPNIPTKQGQNMLEILQ
DCFEEQN-------ST-ESLSCSTPKEKDIYVQ-STGK-----ERQASHSES----VPIS
SRRKE-A-----------SLQVPAKPSDPADEPVQANEVHQKILST-DVVSKSTPDSTKT
SS--KGVKGHHG-ASDELYLPGGSPVVLLGARVSGS--Q------------KAISSGGQK
RVTS--RRSADMQSSNTDIPFKTRKRLNFEDKVISNTAEIESSASQVEDSISEEQ-EGTS
S---ETSQK-RDDLSSEIQPQSKKSFSELYLETVNRKSKC--SSVVRHTAAVPSPPY

ENSGT00390000016737_Linker_0_1 (358, 366)

P--
--PND

PF15620 // ENSGT00390000016737_Domain_1 (366, 740)

MKLLEDEFIIDGPDRSFSSQPWVVIPRKGHH-----MPFP--ENIAVP-QGKK-S
-----------------------REKPHRLSEKTLVSNTQTDK-----------------
-------------------TGPVEEAQLSVEEKL--GTTLTNEVENDCRSTENKTHSENA
KKPSAR--KRTVKQKQRR-PSKPNVAQ-ELSMGQNETENRNMSKI-GQDKLQI--NSKRN
MED---HEEVRNEP----TPKKPVP-ALGNKKEKDST------QANKEKSR-KK------
-CFSRES--------------------KR-KSV--PKEV-TLASRRGRRTSQHPSEWWLV
KPSEGSVDGNS-SKENESS

ENSGT00390000016737_Linker_1_2 (740, 1136)

ILYPNRKKQ-TK-RNHVSENTEKKPVPSKRKKK--EISSRE
L-K---SLNVKGSGG-------ND-DIS-TSQR---KPL---------QNIDADPTQ-KS
LHCSGP--TRGSEDQ--------------NSDM-ISQ-NVHLKTRSE-QHRSKT-QMEST
-------------------SNSEVCKHSVWEESGPSRFK-NLEMPGRSNSEVGDEKDQKS
L---------------DLKTRSSNMVP---NRNLHHKLVLPSNSPNVRRSNRIRLKPLEY
WRGERIDYQESSSGR-LVLEIVSPASESVKR-KAKRNLDKVNKETNKK-RIHLDNPTKT-
-KIKVSLDIPLGDPFQATLAKDPETREIVP-MDLIRPRDTYHFFVE-----QHGL

PF11699 // ENSGT00390000016737_Domain_2 (1136, 1219)

KVYKT
LNTTFFSTGKLVLGPHEEKGKQHVGQDILVFYVNFGDLLCTLHETPYMLTTGDSFYVPSG
NHYNIKNLLNVESCLLFTQIKR------------------------

----------MAASGL

PF15622 // ENSGT00390000016737_Domain_0 (17, 358)

DHLKN-----------GYRRRFCRPSRARDINTQQGQNVLEILQ
DCFEEQSLANDFSTNSTKSVLYSTHKIKDTCIQ-SQSK-----ECQKSHPKS----VPVS
SRKKE-A-----------SLQFVVEPSEATNRSVQAHEVRQKILAT-DVSSKNTSDSKKM
SS--RNINDYHSDAGEEFYLSVGSPSVLLDAKTSVS--Q------------NVIPSSAQK
RETYTFENSVNTLPSSTEVSLKTKKRLNFEDKVMLKKIEIDNKVSDEEYKTSEG-QERKP
S---GSSQNITRDSEYEIQRKAKKSFSTLFLETVKRKSKS--SPVVRHAATAPPHSC

ENSGT00390000016737_Linker_0_1 (358, 367)

P--
--PDDK

PF15620 // ENSGT00390000016737_Domain_1 (367, 740)

KVIEDEFIIDESDQSFASRSWITIPRKAGPLKQ-RPISP-AESTALL-QNRK-S
-----------------------REKHHNILPKTLANGKHSHE-----------------
-------------------PHPVEPSQSSDKTVLDTSYALTGETENDCKSAKYEMCSKDA
EKSSGS--KRTIKQKQRR-KFKAKPAEEQLDVGQSKDENIRMSHT-TQDKFQR--NSDRN
IEE---REEIGNDC----VSKKQMS-PVGSKK--SSA------RKDKGEAK-KK------
-HFSNES--------------------KN-KLV--PEEV-ISTVTRSRRISRRPSDWWVV
KSEESPVYSNS-SIRNELP

ENSGT00390000016737_Linker_1_2 (740, 1136)

VHRNSRQKS-AKKTNQSSKNIGEKTIPLKRQKIATKGNQRV
Q-K---FLNAKGSGG---TV-GHD-EISSCLLS---EPL---------ESDEEDLAKKKN
LDCSRS--TRSSKKE--------------DNVM-TAQ-HVPLKPQTS-GYTYNT-PTESS
-------------------LDSGERKTLVLEESGPSRLNNNYLTSGKNNNDVDEEEVHGS
S--------------DDS--KRSKVIP---KNRIHHKLVLPSNTPNVRRTKRTRLKPLEY
WRGERIDYQGRPSGGFVIGGILSPDTMSSKR-KAKENIGKVDKKSNKK-RICLDNDERKT
-SLMVNLGIPLGDPLQPTRVKDPETREIIL-MDLVRPQDTYQFFVK-----HGEL

PF11699 // ENSGT00390000016737_Domain_2 (1136, 1219)

KVYKT
LDTPFFSTGKLILGPQEEKGKQHVGQDILVFYVNFGDLLCTLHETPYIISTGDSFYVPSG
NYYNIKNLLNEESVLLFTQIKR------------------------

----------MAASGL

PF15622 // ENSGT00390000016737_Domain_0 (17, 107)

DHLKN-----------DYRRRFCRPSRARNINTEQGQNVLEILQ
DCFEEKSLANDFSTNSIKSVLYSTPKIKDTCIQ-SPSK-----E--Q-------------
-----------------------------------ANEVHRKILAT-DVSSKNTSDSKKM
SS--RNINDHHSEADEEFYLSVGSPSVLLDAKTSVS--Q------------NVISSSAQK
RKTYTFENSVNMPPSSTEVSLKTKKRLNFEDKVILRKIEIDNKVSDEEDKTSEG-QERQP
S---GSSQNRMQDSECEIQPQA-KSFSTLFLETIKRKSES--SPIVRHATTAVPHSCP--
--PDDK

PF15620 // ENSGT00390000016737_Domain_1 (367, 740)

ELIEDEFIIDESDKSFASRSWITIPRKPGPLKQ-RITSP-AESTTVL-QGRK-S
-----------------------REKHHNISSKTLTNDKHSQK-----------------
-------------------AHSVETSQPSDETVLDTSNALTGEMVNDCRSTKYEMYSENA
KKSSGS--KRTIKQKQKR-KFKAKLAKEQLDVGQSKDENMYTSHT-TQDKFQR--NSDRN
MEE---REEMGNDR----ASKKQMS-PLGSKK--SSP------RKDKEESK-KG------
-HLSSES--------------------KD-RLV--PEEV-TSTVRRSRRISRRPSNWWVV
KSEESPVYSNS-SIRNELA

ENSGT00390000016737_Linker_1_2 (740, 1136)

VRHDSRQKS-AKKTNQSSKNIRKKTTPLKRQKTATKGSPRV
Q-K---VLNAKGSGG---IV-DHD-EISSCPQS---EPL---------ESDEADLLKKKK
LDCSRS--TGSSKNQ--------------DDIM-TAQ-NVSLKPQTY-GYTCKT-PTESN
-------------------LDSEEHKTSILEESGPSTLK-NYLMSGKKNNDVDDEEVHGS
L--------------DDSRVKLSKVIP---KNRIHHKLVLPSNTPNVRRTKRIRLKPLEY
WRGERIDYQGRPSGGFVVSGILSPDTVPSKR-KAKENVGKVNKGANKK-RICLDNDERKT
-SLMVNLDIPLGDPLQPTSVKDPETREIIL-LDLIRPRDTYQFFVK-----HGEL

PF11699 // ENSGT00390000016737_Domain_2 (1136, 1219)

KVYKT
LDTPFFSTGKLILGPQEEKGKQHVGQDVLVFYVNFGDLLCTLHETPYIISTGDSFYVPSG
NYYNIKNLLNEESVLLFTQIKR------------------------

----------MAGSGL

PF15622 // ENSGT00390000016737_Domain_0 (17, 358)

DHLKN-----------DYRRRFCRPSRAPDINTEQSQNMLEILE
NCFEEKSLIDDFITNSTKSVLYLTPSIKNSGIQ-SPSK-----DCQKSHPKS----FQ--
----E-A-----------TLQGVVEPTEAASGSVQVHEIHQKVLTA-DVCSKSTPDLKKK
SG--KKLNGLCAEADEEFYISVGSPTVLLHGKPSES--Q------------NAIS-SAQK
RETHTFGNSVNMLSSSTEISLKTKKRLNFEDKDILRKVERETNKSEVEDKVSGQ-KERRR
S---ETSPKRVQDVEHEIPSQAKKSFSTLFLETVKRKGES--SPVVRHTAMAPSHSS

ENSGT00390000016737_Linker_0_1 (358, 367)

P--
--PSDA

PF15620 // ENSGT00390000016737_Domain_1 (367, 740)

KLLEDEFIIDESERSFAHQSWITIPKKGRPLNQ-PTVSS-AESAAVL-QDKK-A
-----------------------RQ-HQSVSPVTLTSNKHLHK-----------------
-------------------AHPEEKSRPSSEQKPNTSCILIDELETQ----------SPS
RNK-RK--NRKAKQEQKK-KMNTNVVEEQPATGWSKDEN--MSDI-AQDNLPK--NSGGT
LDD---CEKIRNDD----SAKKEMP-PVENMKTKCRS------KKDKKESR-KK------
-HISRES--------------------KRKEQI--PEEM-TSTVTRSRRISRRPSDWWVV
RSEESPVHSNS--LRNDIS

ENSGT00390000016737_Linker_1_2 (740, 1136)

VYHNSRRKP-AKKTNQSSKNIVKKTVPSKRQKTSTRGSSRV
Q-K---FLNVENSRG---IT-DHD-EVSSCPQK---ESL---------ENDKTDLTKKKN
LDCS--RTTRHSKDQ--------------DEIM-STQ-NVRLKSQIS-EDTCKT-PVESN
-------------------LESGESKASVLEESGPSRLK-NYLMSGNNNSDVNNE-VQES
LDN--------------SRVKGCKVAP---RNNMHYKLVLPSNTPGVRRTKRIRSKPLEY
WRGERVDYQETPSGGFVIGGILSPETVTSKR-KAKGNVEKVNKIHNRK-RICLDNVERKS
-RLVVNCDIPLGDPFQPTQVKDPETREIIL-MDLIRPRDTYQFFVE-----HGEL

PF11699 // ENSGT00390000016737_Domain_2 (1136, 1219)

KVYKT
LDTPFFSTGKLILGPYEEKGKQHVGEDILVFYVNVGDLLCTLHETPYTITTGDSFYVPSG
NYYNIKNLLNEESILLFTQIKR------------------------

----------MAASGL

PF15622 // ENSGT00390000016737_Domain_0 (17, 358)

DHLKN-----------GYRRRFCRPSRARDINTEQGQNVLEILQ
DCFEEKSLANDFSTNSTKSVPNSTRKIKDTCIQ-SPSK-----E--KSHPKS----VPVS
SKKKE-A-----------SLQFVVEPSEATNRSVQAHEVHQKILAT-DVSSKNTPDSKKM
SS--RNINDHHSEADEEFYLSVGSPFVLLDAKTSVS--Q------------NVIPSSAQK
RETYTFENSVNMLPSSTEVSVKTK-------KVMLKKIEIDNKVSDEEDKTSEG-QERKP
S---GSSQNRIRDSEYEIQRQAKKSFSTLFLETVKRKSES--SPIVRHAATAPPHSC

ENSGT00390000016737_Linker_0_1 (358, 366)

P--
--PDD

PF15620 // ENSGT00390000016737_Domain_1 (366, 739)

MKLIEDEFIIDELDQSFASRSWITIPRKAGSLKQ-RTISP-AESTALL-QGRK-S
-----------------------REKHHNILPKTLANDKHSHK-----------------
-------------------PHPVETSQPSDKTVLDTSYALIGETVNNYRSTKYEMYSKNA
EKPSRS--KRTIKQKQRR-KFMAKPAEEQLDVGQSKDENIHISHI-TQDEFQR--NSDRN
MEE---REEMGNDC----VSKKQMP-PVGSKK--SST------RKDKEESK-KK------
-RFSSES--------------------KN-KLV--PEEV-TTTVTKSRRISRRPSDWWVV
KSEESPVYSNS-SVRNEL

ENSGT00390000016737_Linker_1_2 (739, 1136)

PMHHNSSQKS-TKKTNQSSKNIRKKTIPLKRQKTATKGNQRV
Q-K---FLNAEGSGG---IV-GHD-EISRCSLS---EPL---------ESDEADLAKKKN
LDCSRS--TRSSKNE--------------DNIM-TAQ-NVPLKPQTS-GYTCNI-PTESN
-------------------LDSGEHKTSVLEESGPSRLNNNYLISGKN--DVDDEEVHGS
S--------------DDS--KQSKVIP---KNRIHHKLVLPSNTPNVRRTKRTRLKPLEY
WRGERIDYQGRPSGGFVISGVLSPDTISSKR-KAKENTGKVNKKSNKK-RICLDNDERKT
-NLMVNLGIPLGDPLQPTRVKDPETREIIL-MDLVRPQDTYQFFVK-----HGEL

PF11699 // ENSGT00390000016737_Domain_2 (1136, 1219)

KVYKT
LDTPFFSTGKLILGPQEEKGKQHVGQDILVFYVNFGDLLCTLHETPYILSTGDSFYVPSG
NYYNIKNLRNEESVLLFTQIKR------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------MERQTEIQR-----------SEGP-----
-----------------------------QVTTQEKIVP----EKRTKC----------S
S----------VPSEQKK----KSLSSAFLMAVTT------GTDEKRHSSLIPPASPSPV
KDLDLGMEDECEFLIDESD-GFSFTSWFSIPKKNKKVEKQALAKP-VPKPQPS-ERKKAV
VRESKKRKDRRAQNEVTVKQTRMEQSKMD--PCNVAEGIQDES-QNSLDVNLVLTEKKEN
TLKSVRQSGPHIEESKKHT---HGQRSTR--TP---NEKKSPVLK--QIQPKKFTF----
--LI----SESDTETSDTEQHK-----PTEIAHEDSFGPCNTTEQ-PQEKIASSEEDHSS
PEPPRSILKTALCSSHKKQTAKQKLSKVASSKKLVENQRNKVRKSALKSTSRKTRVLISG
ESSDSEP-----IEEVNERELLKS----NKVNAPSLQQESQTPILHKSHQSVKLK-----
---------NVI-HSLESSGNV---Y--I----KTPAK---SKEPLQNLINYPENTGERK
KASAKS------LQQTATQINQRT-DMIDCSHSENAELGNTTVHKD---SSDQNMAEQK-
DKKSNA--SVKTKYKKKSNACRSQISPAPE-RN---------------------------
----------------------------KSHSSGPVLNRYVKFTSKNAEPI-AYEWEDSS
S--------------DKSMVLKDQASE-FLPNSLGHKLVMPSHTPNVRRTKRIRLKPLDY
WRGERVNYLSRPSGGFVVGGITYPKKESCRE-AKKRRKHTPK----T-------------
RSHVEHLNISLADASKPTVVWDPTVNGEVL-QECVNTGRNHSCFFN-----DESVEIYKN
LNTSGFAAGKLILKPLKE

PF07883 // ENSGT00390000016737_Domain_2 (1159, 1213)

KGHQFVHTDKIAFHVIHGKIIVTLHKTSYYLTTGDFFYVPEG
NGYNIHNLLNEESILLFTQLKGERPIIED--SVNESSSS-------

----------MAASGL

PF15622 // ENSGT00390000016737_Domain_0 (17, 358)

DHLKN-----------GYRRRFCRPSRARDINTQQGQNVLEILQ
DCFEEQSLANDFSTNSTKSVLYSTHKIKDTCIQ-SRSK-----ECQKSHPKS----VPVS
SRKKE-A-----------SLQFVVEPSEATNRSVQAHEVRQKILAT-DVSSKNTSDSKKM
SS--RNINDYHSDAGEEFYLSVGSPSVLLDAKTSVS--Q------------NVIPSGAQK
RETYTFENSVNTLPSSTEVSLKTKKRLNFEDKVMLKKIEIDNKVSDEEYKTSEG-QERKP
S---GSSQNITRDSEYEIQRKAKKSFSTLFLETVKRKSKS--SPVVRHAATAPPHSC

ENSGT00390000016737_Linker_0_1 (358, 367)

P--
--PDDK

PF15620 // ENSGT00390000016737_Domain_1 (367, 740)

KVIEDEFIIDESDQSFASRSWITIPRKAGPLKQ-RPISP-AESTTLL-QNRK-S
-----------------------REKHHNILPKTLANGKHSHE-----------------
-------------------PHPVEPSQSSDKTVLDTSYALTGETENDCKSAKYEMCSKDA
EKSSGS--KRTIKQKQRR-KFKAKPAEEQLDVGQSKDENIRMSHT-TQDKFQR--NSDRN
IEE---REEIGNDC----VSKKQMS-PVGSKK--SSA------RKDKGEAK-KK------
-HFSNES--------------------KN-KLV--PEEV-ISAVTRSRRISRRPSDWWVV
KSEESPVYSNS-SIRNELP

ENSGT00390000016737_Linker_1_2 (740, 1136)

VHRNSRQKS-AKKTNQSSKNIGEKTIPLKRQKIATKGNQRV
Q-K---FLNAKGSGG---TV-GHD-EISSCLLS---EPL---------ESDEEDLAKKKN
LDCSRS--TRSSKKE--------------DNVM-TAQ-HVPLKRQTS-GYTYNT-PTESS
-------------------LDSGERKTLVLEESGPSRLNNNYLTSGKNNNDVDEEEAHGS
S--------------DDS--KRSKVIP---KNRIHHKLVLPSNTPNVRRTKRTRLKPLEY
WRGERIDYQGRPSGGFVIGGILSPDTMSSKR-KAKENIGKFDKKSNKK-RICLDNDERKT
-SLMVNLGIPLGDPLQPTRVKDPETREIIL-MDLVRPQDTYQFFVK-----HGEL

PF11699 // ENSGT00390000016737_Domain_2 (1136, 1219)

KVYKT
LDTPFFSTGKLILGPQEEKGKQHVGQDILIFYVNFGDLLCTLHETPYIISTGDSFYVPSG
NYYNIKNLLNEESVLLFTQIKR------------------------

MKNLTFYQTDDLLFFQ

PF15622 // ENSGT00390000016737_Domain_0 (17, 358)

DHLKN-----------DYRRRFCRPSRAPDINTEQGQNILEVLL
DCFEEKSLASDVSKNATKSVLYSTPKTKDICVQ-SSSKE---TQSPKSHPKS----GPVS
SRKKE-A-----------PLQLTVELNEAVNKSVQDHEVHQKILAT-DVHSKNTSDLRKM
SS--KKLKDNHSEADEDCYLSVGSPSD-LDIKASSL--Q------------KGSPSVAQK
RETHTSKNSVNMLSSSPEISHKTRKRLSFEDKDVLKKVEITNEVSEIEDKVSEGLQDRKQ
S---RTSQKRIQDSEYENQPQARKSFSTLFLETVKRKSES--SSVVRHIATVPPHLS

ENSGT00390000016737_Linker_0_1 (358, 366)

P--
--ANN

PF15620 // ENSGT00390000016737_Domain_1 (366, 740)

TKLLEDEFIIDESDKSFVSQPWITIPRKTGPLKQ-HTASP-AEST-VL-QRKK-S
-----------------------RERHDSVSSVALTSNKHPGK-----------------
-------------------AHPVEKSQPSEPKIPGGSCALSDDVENNCKSTKYEIYSENA
KKSSGD--KRTIKQKQRT-KSEANVPEEEVNVRQSKDKNINISHT-VQDKLQR--NSDEN
MEE---DEEI-SVS----ISKNQLL-SVGSKKGSTNVPHKKNQKKDKE-CR-KK------
-HFSSGS--------------------KNNKIE--PEEL-TSTIRRSQRISRCPSDWWVV
KSEQSSFSSSSS-VRNELS

ENSGT00390000016737_Linker_1_2 (740, 1136)

VYHNSRQKPPAEKTNQSSKNIGKKAAPFKKQKRANKGSSGA
Q-----VLYAKDSGG---A------------QN---ESL---------GSNEADLAKKKN
PNPPGD--TGSSKNQ--------------DS-M-AAQ-NVHQKSQMS-VYTCTT-PTKSN
-------------------LDSGEPGTSVLEGSGPVRLK-NYLTSGKNNSDVDDNVVQEN
L--------------NDSRGEISDSTP---ESKMHHKLVLPSYTPNVRRTMRTRSKPLEY
WRGERIDYQARPSGGFVIGGILSPDTVSSKR-KAKGNLGRIITTANRK-RICLENEERKN
-KFMVNLNIPLGDPLQPTRVKDPETQETVL-MDLIRPRDTYQFCVE-----HDEL

PF11699 // ENSGT00390000016737_Domain_2 (1136, 1219)

KVYKT
LDTPFFSSGKLIIGPLQEKGKQHVGLDTLVFYVKLGYLLCTLHETPYIVTTGDSFYVPSG
NYYNIKNLLNEESVLLFTQIKS------------------------

----------MAASGL

PF15622 // ENSGT00390000016737_Domain_0 (17, 325)

DHLKN-----------GYRRRFCRPSRARDINTEQGQNVLEILQ
DCFEEKSLANDFSTNSTKSVLNSTRKIKDTCIQ-SPSK-----ECQKSHPKS----VPLS
SRKKE-A-----------SLQFVVEPSEATNRSVQAHEVRQKILAT-DVSSKNTPDSKKM
SS--RNINDHHSEADEEFYLSVGSPYVLLDAKTSVS--Q------------NVIPSSAQN
RETYTFENSVNMLPSSTEVSLKT-------------------------------------
----------------------KK

ENSGT00390000016737_Linker_0_1 (325, 366)

SFSTLFLETVKRKSES--SPIVRHGGIAPPHSCP--
--PDD

PF15620 // ENSGT00390000016737_Domain_1 (366, 739)

MKLIEDEFIIDESDQSFA-----------GPLKQ-RTISP-AESTALL-QDRK-S
-----------------------RAKHHNILAKTLANDKHSHK-----------------
-------------------PHLVETSQPSDKTVLDTSYALTGETENDCRSTKYEMYSKNA
EKSSRS--KRTIKQKQRR-KFMAKPAEEQLDVGQTKDENIHMSHI-TQDKFQR--NSDRN
MEE---REEMGNDC----ASKKQMP-PVGSKK--SST------RKDKEESK-KK------
-RFSSES--------------------KN-KLV--SEEV-TSTVTRSRRISRHPSNWWVV
KSEESPVYSNS-SIRNEL

ENSGT00390000016737_Linker_1_2 (739, 1136)

PLHPNSRQKS-AKKTNQ--------------QKTATKDSQRV
Q-K---FLNAKGSGG---II-GHD-EISSCLLS---EPL---------ESDEADLAKRKN
LDCSRS--TGSSKNE--------------DNIM-TAQ-NVPLKPQTS-GYICNT-PTESN
-------------------LDSGEHKTSVLEESGPSRLNNNYLMSGKNNNDVDDEEVPGS
S--------------DDS--KRSKVIP---KNRIHHKLVLPSNTPNVRRTKRTRLKPLEY
WRGQQIDYQGRPSGRFVISGILSPGKISSKR-KARENIG-------KK-RICLDNDERKT
-SLMVNLGIPLGDPLQPAMVKDPETREIIL-MDLVRPQDTYQFFVK-----HGEL

PF11699 // ENSGT00390000016737_Domain_2 (1136, 1219)

KVYNT
LDTPFFSTGKLVLRPQEEKGKQHVGQDILFFYVNFGDLLCTLHEIPYIISTGDSFYVPSG
NYYNIKNLLNEESVLLFTQIKR------------------------

---------MAAASGL

PF15622 // ENSGT00390000016737_Domain_0 (17, 358)

DHLKN-----------EYRRRFCRPSRAPAINTKEGQNILEILQ
DCFEEKSFANDFSTNSTKSVLFSTPKVGDICIQ-SPSKE---AQCQKSHLKS----VPVS
SRKKE-S--------------------EGVNRSAQDHEVHQQILA--TVGSKNTPGLRRT
SS--KKLRDHHSEASEKFHLSVGSPVVLLDAKASVL--Q------------NAVPSVAQK
RETYTSENSVNTLPSSTEISLKTRKRLNFEEKSVLKKGEIANKVSEIEDKVSEETQKRRS
L---RISQKRVQDSEDEIQPQTKKSFSTLFLETVKRKSES--SPVVRHIATAPPHSS

ENSGT00390000016737_Linker_0_1 (358, 367)

P--
--SNDL

PF15620 // ENSGT00390000016737_Domain_1 (367, 739)

TLLEDEFIIDESESSIASQPWITIPRKAGSLKQ-CTVYP-AESSALL-QSKK-S
-----------------------KEKHHSVSPTALTSDKHSDT-----------------
-------------------AYAVETSPPSEQRRLGRSCASTNELENDYRSTKHEMYYENA
EKSSGK--KKTIQQQERG-KFKANILEEQVDMEQSKDNNINVSHI-TQDKLQR--NSDRN
MEE---CEKVINVG----ISKKQML-PVGSKKNSTNVPYTVYQKKDKK-SK-KK------
-HFPSGS--------------------KKNKLI--PDEV-TSTITRSRRISRHPSDWWVV
KSEQSHVYSNSP-RRNEL

ENSGT00390000016737_Linker_1_2 (739, 1136)

SLSYDCRQKL-AEKPNQSSKNTKEKTIPFKERKITTSGSSGA
Q-E---FLNAKDSGR---VT-DHD-EISGCCQN---ESL---------ESDEEDLVTKKN
--HSGG--IGNPKKQ--------------DN-M-TAQ-NVHLKSQIK-EFTCKT-PAESN
-------------------LDSGEPKTSVLEGSGPFRVK-NYLTSGKNNSDVDDREVSES
S--------------SDSSLKLPPIIS---EHKIHHKLVLPSNTPNVRRTKRTRLKPLEY
WRGERIDYHGRPSGGFVIGGILSPDTVSSKT-KSKGNVGKVKKMANRK-RICLDDEERKK
-KFMVNLNIPLGDPLQPTRVKDPETREIVT-MDLLRPRDTYEFFIE-----HDEL

PF11699 // ENSGT00390000016737_Domain_2 (1136, 1219)

KVYKT
LDTPLFSTGKLILGPHQEKGKQHVGSDILVFYVNFGDLLCTLHETSYIITAGDSFYVPSG
NYYNIKNLLNEESVLLFTQIKR------------------------

----------MAASGL

PF15622 // ENSGT00390000016737_Domain_0 (17, 358)

DHLKN-----------GYRRRFCRPSRARDINTQQGQNVLEILQ
DCFEEQSLANDFSTNSTKSVLYSTHKIKDTCIQ-SRSK-----ECQKSHPKS----VPVS
SRKKE-A-----------SLQFVVEPSEATNRSVQAHEVRQKILAT-DVSSKNTSDSKKM
SS--RNINDYHSDADEEFYLSVGSPSVLLDAKTSVS--Q------------NVIPSSAQK
RETYTFENSVNMLPSSTEVSLKTKKRLNFEDKVMLKKIEIDNKVSDEECKTSEG-QERKP
S---GSSQNITRDSEYEIQRKAKKSFSTLFLETVKRKSKS--SPVVRHAATAPPHSC

ENSGT00390000016737_Linker_0_1 (358, 367)

P--
--PDDK

PF15620 // ENSGT00390000016737_Domain_1 (367, 740)

KVIEDEFIIDESDQSFASRPWITIPRKARPLKQ-RSISP-AESTALL-QNRK-S
-----------------------RERRHNILPKTLANGKHSHE-----------------
-------------------PHPVETSRSSDKTVLDTSYALTGETENDCRSTKYEMCSKDA
EKSSRS--KRTVKQKQRR-KFKAKPAEEQLDVGQSKDENIRMSHS-TQDKFQR--NTDRN
MEE---REEIGNDC----VSKKQMS-PVGSKK--SSA------RKDKGEAK-KK------
-HFSSES--------------------KN-KLV--PEEV-ISTVTRSRRISRRPSDWWVV
RSEESPVYSNS-SIRNELP

ENSGT00390000016737_Linker_1_2 (740, 1136)

VLRNSRQKS-AKKTNQSSKNIGEKTIPLKRQKTTTKGNQRV
Q-K---FLNAKGSGG---TV-GHD-EISSCLPS---EPL---------ESDEEDLAKKKN
LDCSRS--TRSSNNE--------------DNVM-TAQ-HVPLKPQTS-GYTYNT-PTESS
-------------------LDTGERKTLVLEESGPSRLSNNYLMSGKNSNDVDEEEVHGS
S--------------DNS--KQSKVIP---KNRIHHKLVLPSNTPNVRRTKRTRLKPLEY
WRGERIDYQGRPSGGFVIGGILSPDTVSSKR-KAKENNGKVDKKSNKK-RICLDNDERKT
-SLMVNLGIPLGDPLQPTRVKDPETREIIL-MDLVRPQDTYQFFVK-----HGEL

PF11699 // ENSGT00390000016737_Domain_2 (1136, 1219)

KVYKT
LDTPFFSTGKLILGPQEEKGKQHVGQDILVFYVNFGDLLCTLHETPYIISTGDSFYVPSG
NYYNIKNLLNEESVLLFTQIKR------------------------

----------MAASGL

PF15622 // ENSGT00390000016737_Domain_0 (17, 358)

DHLKN-----------GYRRRFCRPSRARDINTQQGQNVLEILQ
DCFEEQSLANDFSTNSTKSVLYSTHKIKDTCIQ-SRSK-----ECQKSHPKS----VPVS
SRKKE-A-----------SLQFVVEPSEATNRSVQAHEVRQKILAT-DVSSKTTSDSKKM
SS--RNINDYHSDAGEEFYLSVGSPSVLLDAKTSVS--Q------------NVIPSSAQK
RETYTFENSVNTLPSSTEVSLKTKKRLNFEDKVMLKKIEIDNKVSDEEYKTSEG-QERKP
S---GSSQNITRDSEYEIQRKAKKSFSTLFLETVKRKSKS--SPVVRHAATAPPHSC

ENSGT00390000016737_Linker_0_1 (358, 367)

P--
--PDDK

PF15620 // ENSGT00390000016737_Domain_1 (367, 740)

KVIEDEFIIDESDQSFASRSWITIPRKAGPLKQ-RPISP-AESTALL-QNRK-S
-----------------------REKHHNILPKTLANGKHSHE-----------------
-------------------PHPVEPSQSSDKTVLDTSYALTGETENDCKSAKYEMCSKDA
EKSSGS--KRTIKQKQRR-KFKAKPAEEQLDVGQSKDENIRMSHT-TQDKFQR--NSDRN
IEE---REEIGNDC----VSKKQMS-PVGSKK--SSA------RKDKGEAK-KK------
-HFSNES--------------------KN-KLV--PEEV-ISAVTRSRRISRRPSDWWVV
KSEESPVYSNS-SIKNELP

ENSGT00390000016737_Linker_1_2 (740, 1136)

VHHNSRQKS-AKKTNQSSKNIGEKTIPLKRQKIATKGNQRV
Q-K---FLNAKGSGG---TV-GHD-EISSCLLS---EPL---------ESDEEDLAKKKN
LDCSRS--TRSSKKE--------------DNVM-TAQ-HVPLKPQTS-GYTYNT-PTESS
-------------------LDSGERKTLVLEESGPSRLNNNYLTSGKNNNDVDEEEAHGS
S--------------DDS--KRSKVIP---KNRIHHKLVLPSNTPNVRRTKRTRLKPLEY
WRGERIDYQGRPSGGFVIGGILSPDTMSSKR-KAKENIGKVDKKSNKK-RICLDNDERKT
-SLMVNLGIPLGDPLQPTRVKDPETREIIL-MDLVRPQDTYQFFVK-----HGEL

PF11699 // ENSGT00390000016737_Domain_2 (1136, 1219)

KVYKT
LDTPFFSTGKLILGPQEEKGKQHVGQDILVFYVNFGDLLCTLHETPYIISTGDSFYVPSG
NYYNIKNLLNEESVLLFTQIKR------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
MLK-----AERSGTERKEG--PTPKRSDR-DEP---S--QAPEVGETGLAPHDALR----
------------A-----SVSP-----SRVAP-RRPPAP-------------SSRETRRP
SAKPKPGAETRQRPRRRKQD----PG------KMTRSERREAERSVGENGR--------T
VGSGHRP-----AEER-EGEAAGS---ETPGVTNPTGQNCPPPGSRDPAMSAGYSNLRCP
SA-LSSASSGIA-SRKESPAARGKRT--NRGGRKRPLPPAGERTPPAELQKS--------
----------------AGPARPEP-EKLVYSSSGVSDPGNVLAGDE---PSGSGAGGSRA
GSDSEP--SPRSKGRRGSAAKRKARRAGAAGLPE---------------ESLES-P-EFA
HPPEEAKTP------RGT-----LRSPLTPDTTGPVTSTVEG-----SGPA-RSRITRTF
P--------------PGDEVR--------VYEQEDLSSVLPTDTPNVRRTKRIRVKPLEY
WRGERVDYKVRPSGGFEIHGIISPDAVSPYR-GASGKMEKLKKLAKEKGRPLAKAKS---
RNAIANLNLSLGDPSKPTTVWCHDTNREVL-LSCVRPKGTYTYCLG-----DDSLM

PF11699 // ENSGT00390000016737_Domain_2 (1137, 1219)

VYKS
LNTSSFSAGQLVLGPFKVKGSQHVCFDTLVFYIVQGELICTLRKTPYYLTAGDTFYVPPG
NLYNIQNLLNQKSVLLFTQIKSERLEGVRLESD--ADDEG------

----------MAASGL

PF15622 // ENSGT00390000016737_Domain_0 (17, 358)

DHLKN-----------DYRRRFCRPCRARDINTEQGQNVLEILQ
DCFEEKSLANDFSTNSIKSVLYSTPKIKDTCIQ-SPSK-----E--KSHPKS----VPVS
SRKKE-A-----------SLQFIVEPSEVTNRSVQAHEVHQKILAT-DVSSKNTSDSKKM
SS--RNINDHHSEANEEFYLSVGSPSVLLDAKTSVS--Q------------NVISSSTQK
RETYTFENSVNRLPSSTDISLKTKKRLNFEDKVILRKVEID-KVSDEDDKTSEG-QERQP
S---ESSQNRMQDSEYEIQRQA-KSFSTLFLETIKRKSES--SPIVRHATTALPHSC

ENSGT00390000016737_Linker_0_1 (358, 367)

P--
--PDDK

PF15620 // ENSGT00390000016737_Domain_1 (367, 740)

ELIEDEFIIDESDKSFASRSWITIPRKTGPLKQ-RITSP-AESTTLL-QGRK-S
-----------------------REKHHNISPKTLTNDKHSHK-----------------
-------------------PHSVETSQPSDKTVLDTSNALTGEMVNDCGSKKYEMYSENA
KKSSGS--KRTMKQKQRR-KFKAKLAKEQLDMGQSKDENMYTSHI-TQDKLQK--NSDRN
TEK---HEEMGNDC----ASKKQMS-PLGSKK--SST------RKDKEESK-KR------
-HLSSES--------------------KD-KLV--PEDV-TSTVTRSRRVSRRPSNWWVV
KSEESPVYSNS-SIRNELTVRHDSRQKS-AKKTNQTSKNIRKKTTPLKRQKTATKGSPRV
Q-K---ILNAKGSGS---IV-GHD-EISSCSQS---EPL---------ESDEADLAKKKS
LDCSRS--TGSSKNQ--------------DDIM-TAH-NVPLKPQTY-GYTCKT-PTESN
-------------------LDSGEHKTSILEESGPSTLK-NYLMSRKKNNDVDDEKVHGS
L--------------DDSRVKRSKVIP---KNRIHHKLVLPSNTPNVRRTKRIRLKRLEY
WRGERIDYQGRPSGGFVVSGVLSPDPVPSKR-KAKENIGKVDKRANKK-RICLDNDERKT
-SLMVNLDIPLGDPLQPTRVKDPETREIIL-MDLIRPRDTCQFFVK-----HGELKVYKT
LDTPFFSTGKLILGPQEEKGKQHVGQDILVSIYIFICLYFAIGRTLI-------------
--YRV-----------------------------------------

----------MASFHLVSAGLGRACRDASLALCSTGCISGLS

PF15622 // ENSGT00390000016737_Domain_0 (43, 192)

GAANIHTKEGQNMLEILQ
DCFEDQSKASFLDDFT-ESLTSSTQKKKANYSQ-SSSK-----KCPVSHSKP----VPVS
SRTGE-A-----------SLQASAEPREAAGGSVQANEV---------------------
---------HHG-ASDELDLCVGSPVVCLDANVSTL--Q------------KAVSSAGQK
RVASVSRSPVDRQASNKNISFKTRKRLNFEDKVTSSTAETENSVLQVEDNLSEGQ-EGTS
S---EITQK-RDDLSSEVLSRSKKNFSELFLETVKRKSKS--SSVVRHTAAVLSSPPP--
--PSD

PF15620 // ENSGT00390000016737_Domain_1 (366, 740)

MKLLEDEFIIDRSDRSFSSRLWVMIPSKDRHLSP-HKPSS--ENTALL-QGKK-S
-----------------------REKSHSLSATTFVRNTQSDK-----------------
-------------------THPIEEAQLSVEENL--GTTCTDELENDCRSPENKMQSETA
KKPPAW--ERTTKQNQRR-VSKPKEAE-ELSKGQSNCENSNMSNT-GQDKLQI--NLKRN
MKD---CEEVRNEP----TPKKHKP-ALENEKKNNST------QTNKGKSG-KK------
-FFSGGS--------------------KN-KSV--SKKV-TLTSRRDCRISRRPSDWWRV
KSDESSVDRNS-LKENNSSVVYPNKKKQ-TK-RNHVSKSTGKKPGPSKRQKT--EMSSRV
Q-T---SLNVKGSGG---TVSGHD-DIS-RSQR---KPL---------KNIEADPTQ-KS
LAISRP--KRGCKYQ--------------NHVT-TSP-NVHLKSHTE-EYTSKT-QMESA
-------------------SNSETSKRSVWEESGPSRFK-NYEMPGSSNSEMGDEQDQKS
L---------------HFTTRSSNMVP---DKKLHHKLVLPSNSPNVRRSNRIRLKPLEY
WRGERVDYQESSSGQ-LVLEIISPASVPTKI-KAQRNLGKVNKKVTKK-QTHLNSHKKT-
-KMELPLDIRLGDPFQATLAKDPETAEVVP-MDLIRPRDTYRFFVE-----HHGLKVFKT
LDTIFFSTGKLVLGPYEEKGKQHVGQDILV-----------------------------G
NHYNIKNLLNVESSLLFTQIKR------------------------

----------MAASGLDHLKN-----------DYRRRFCRPSRARNINKEQGQNMLEFLQ
DCFEERSLANDFSTNSTKSVLCSTPKVKDSCFQ-SPGK-----EIQKSCPKS----VPVS
SKKKE-D-----------FLPCFEEPSKTSNRSVQAYEVHQKSLAT-DVGSRNTPDSKKI
SS--RKLDDYESESDEEFYLSVGSPSVVLSAKTSTS--Q------------NAIPSVAQK
RETYIFENSENMLSSSTEISLKTKKRLNFEDKDILKNIEIENEVSEVEDKISER-QERKQ
S---ETSQKRIQSLELEIQPQATKRFSTLFLETVTRKSES--SPIVRHTATASPHLSP--
--PNDPKLLEDEFIIDESNRSFASHSWISIPRKVGPLKQ-RSVPP-TESTAVP-QVKK-S
-----------------------KERHHSISPTTSTHDNHLDG-----------------
-------------------SHPVEKSLPCDDKKQSMSCALTDEVDNNSRSTKCETHSKNK
GKSSGN--KKTVKQKKKK-KYKANVVEEQLHMGQSKEENINAHKKHIAPKLQR--SSSRN
MKD---CEEMRNDH----ISKM-VP-SVGSKQKKSTK------KQDKQESI-KK------
-HSPSES--------------------KN-NLV--PEKV---TVLRSRRISRRPSDWWVV
KSQESPAYSDYSSIRNELSVHHNSGQKP-AKTRNQSSKNIGKKAIPPKKQKTPTQGSRRA
Q-K---VVHDKGSGG---LS-VRG-EIPDCSQN--NKPV---------ESDESDLATKKN
LSCSRS--VESSKEQ--------------DGIM-TAQ-NVHLKSQSN-ECTCKT-PTGFN
-------------------LDSVEPKPLVLEESGPARLK-NNLMSRKKNSDVNDEDIQDS
L--------------DYKRVKRSQVTS---EKKVHHKLVLPSNTPNVRRTKRIRLKPLEY
WRGERIDYQGTPSGGLVIGGVLSPDAVVPKR-KAKGNMEKVNKVANGK-RICLDNTERKN
-RLMVNLDIPLGDPCQPTRVKDPETREFIL-MDLIRPRDTYQFFVE-----HGEL

PF11699 // ENSGT00390000016737_Domain_2 (1136, 1219)

KVYKT
LDTPFFSTGKLILGPHEEKGKQHVGPDILVFYVNFGDLLCTLHETPYLLTTGDSFFVPSG
NYYNIKNLLNEESVLLFTQIKR------------------------

----------MAASGL

PF15622 // ENSGT00390000016737_Domain_0 (17, 358)

DHLKN-----------GYRRRFCRPSRARDINTQQGQNVLEILQ
DCFEEQSLANDFSTNSTKSVLYSTHKIKDTCIQ-SRSK-----ECQKSHPKS----VPVS
SRKKE-A-----------SLQFVVEPSEATNRSVQAHEVRQKILAT-DVSSKNTSDSKKM
SS--RNINDYHSDAGEEFYLSVGSPSVLLDAKTSVS--Q------------NVIPSSAQK
RETYTFENSVNTLPSSTEVSLKTKKRLNFEDKVMLKKIEIDNKVSDEEYKTSEG-QERKP
S---GSSQNITRDSEYEIQRKAKKSFSTLFLETVKRKSKS--SPVVRHAATAPPHSC

ENSGT00390000016737_Linker_0_1 (358, 367)

P--
--PDDK

PF15620 // ENSGT00390000016737_Domain_1 (367, 740)

KVIEDEFIIDESDQSFASRSWITIPRKAGPLKQ-RPISP-AESTALL-QNRK-S
-----------------------REKHHNILPKTLANGKHSHE-----------------
-------------------PHPVEPSQSSDKTVLDTSYALTGETENDCKSAKYEMCSKDA
EKSSGS--KRTIKQKQRR-KFKAKPAEEQLDVGQSKDENIRMSHT-TQDKFQR--NSDRN
IEE---REEIGNDC----VSKKQMS-PVGSKK--SSA------RKDKGEAK-KK------
-HFSNES--------------------KN-KLV--PEEV-ISTVTRSRRISRRPSDWWVV
KSEESPVYSNS-SIRNELP

ENSGT00390000016737_Linker_1_2 (740, 1136)

VHRNSRQKS-AKKTNQSSKNIGEKTIPLKRQKIATKGNQRV
Q-K---FLNAKGSGG---TV-GHD-EISSCLLS---EPL---------ESDEEDLAKKKN
LDCSRS--TRSSKKE--------------DNVM-TAQ-HVPLKPQTS-GYTYNT-PTESS
-------------------LDSGERKTLVLEESGPSRLNNNYLTSGKNNNDVDEEEVHGS
S--------------DDS--KRSKVIP---KNRIHHKLVLPSNTPNVRRTKRTRLKPLEY
WRGERIDYQGRPSGGFVIGGILSPDTMSSKR-KAKENIGKVDKKSNKK-RICLDNDERKT
-SLMVNLGIPLGDPLQPTRVKDPETREIIL-MDLVRPQDTYQFFVK-----HGEL

PF11699 // ENSGT00390000016737_Domain_2 (1136, 1219)

KVYKT
LDTPFFSTGKLILGPQEEKGKQHVGQDILVFYVNFGDLLCTLHETPYIISTGDSFYVPSG
NYYNIKNLLNEESVLLFTQIKR------------------------

----------MAASGLDHLKN-----------DYRRRFCRPCRAPDIKTKQGQNILEILQ
DCFEENSLANDFSTNSTKSLLYSTPKTGDICIQ-SPSKE---AECQKSHLNS----VPVS
LRKKE-A-----------SV-----PSEVDSRSGQDHEVHQQILTA-GIGSKSTPGSRKM
SS--KKLKDCHSEADKELHLPVGSPFVLLDAKASVS--Q------------NVISSIAQK
K------NSVNTLSSSMEISLKTRKRLNFEDKIALKEVEIANKIPEIEDKGSEEPQERKL
S---RASQKRVPDLEDEIHPQTKKSFSTLFLETVKRKSES--SPVVRHIATAPLHSSP--
--SNDVNLLEDEFIIEESERSFASQSWITIPRKAGPLKQ-CTVNP-AENSALL-QSKK-S
-----------------------REKHHRVPPANMTSDRHCDT-----------------
-------------------AYPVEKSQPSKQKRLG

PF03430 // ENSGT00390000016737_Domain_1 (516, 663)

KGCALANELENHCGSTKYEMYNENA
EKSSGK--KKTIKQKQRR-KYKGNVLEEQVDVAQSKEKNTNMSHI-TQGDNTQGKNISRN
YRE---IEEADSEV----YSIKQCE-KLGSKKNSTNVPYTENQKKDKE-YK-KK------
-L

ENSGT00390000016737_Linker_1_2 (663, 1136)

FPSGS--------------------KKNKLV--PDEV-TSTITRSRRISRRPSNWWVV
KSDQSLLYSNSP-RRNELSVCHNSRRKP-TEKSNQSTKNIEEKTIPFKGQKSTTSGSSRA
Q-E---FLNAKDSGR---II-DHD-EISSCSQN---ESL---------ENDKEDLAKKKN
LLSRLG--TRSTKDQ--------------DN-M-SER-NVHQESQIK-GFTRNT-PAESN
-------------------FDSREQKISVLEGSGPCRLK-NYLTPGKNNSDVDDKEVQET
S--------------SDSRVKISTVIP---QDKIHHKLVLPSNTPNVRRTKRTRLKPLEY
WRGERIDYHGRPSGGFVIGGILSPDTVSSKR-KSKGNTGKVNKMVARK-RICLDNEERKN
-KFMINLSIPLGDPLKPTRVKDPETREIIP-MDLLRPRDTYQFCVE-----HHEL

PF11699 // ENSGT00390000016737_Domain_2 (1136, 1219)

KVYKT
LDTPIFSTGKLILGPHQEKGKQHVGSDILVFYVNFGDLLCTLHETPYIITTGDSFYVPSG
NYYNIKNLLNEESVLLFTQIKR------------------------

----------MAASGL

PF15622 // ENSGT00390000016737_Domain_0 (17, 358)

DHLKN-----------GYRRRFCRPSRARDINTQQGQNVLEILQ
DCFEEQSLANDFSTNSTKSVLYSTHKIKDTCIQ-SRSK-----ECQKSHPKS----VPVS
SRKKE-A-----------SLQFVVEPSEATNRSVQAHEVRQKILAT-DVSSKTTSDSKKM
SS--RNINDYHSDAGEEFYLSVGSPSVLLDAKTSVS--Q------------NVIPSSAQK
RETYTFENSVNTLPSSTEVSLKTKKRLNFEDKVMLKKIEIDNKVSDEEYKTSEG-QERKP
S---GSSQNITRDSEYEIQRKAKKSFSTLFLETVKRKSKS--SPVVRHAATAPPHSC

ENSGT00390000016737_Linker_0_1 (358, 367)

P--
--PDDK

PF15620 // ENSGT00390000016737_Domain_1 (367, 740)

KVIEDEFIIDESDQSFASRSWITIPRKAGPPKQ-RPVSP-AESTALL-QNRK-S
-----------------------REKHHNILPKTLANGKHSRE-----------------
-------------------PHPVEPSQSSDKTVLDTSYALTGETENDCKSAKYEMCSKDA
EKSSGS--KRTIKQKQRR-KFKAKPAEEQLDVGQSKDENIRMSHT-TQDKFQR--NSDRN
IEE---REEIGNDC----VSKKQMS-PVGSKK--SSA------RKDKGEAK-KK------
-HFSNES--------------------KN-KLV--PEEV-ISAVTRSRRISRRPSDWWVV
KSEESPVYSNS-SIRNELP

ENSGT00390000016737_Linker_1_2 (740, 1136)

VHRNSRQKS-AKKTNQSSKNIGEKTIPLKRQKIATKGNQRV
Q-K---FLNAKGSGG---TV-GHD-EISSCLLS---EPL---------ESDEEDLAKKKN
LDCSRS--TRSSKKE--------------DNVM-TAQ-HVPLKPQTS-GYTYNT-PTESS
-------------------LDSGERKTLVLEESGPSRLNNNYLTSGKNNNDVDEEEAHGS
S--------------DDS--KRSKVIP---KNRIHHKLVLPSNTPNVRRTKRTRLKPLEY
WRGERIDYQGRPSGGFVIGGILSPDTMSSKR-KAKENIGKVDKKSNKK-RICLDNDERKT
-SLMVNLGIPLGDPLQPTRVKDPETREIIL-MDLVRPQDTYQFFVK-----HGEL

PF11699 // ENSGT00390000016737_Domain_2 (1136, 1219)

KVYKT
LDTPFFSTGKLILGPQEEKGKQHVGQDILVFYVNFGDLLCTLHETPYIISTGDSFYVPSG
NYYNIKNLLNEESVLLFTQIKR------------------------

----------------

PF15622 // ENSGT00390000016737_Domain_0 (17, 195)

DHLKN-----------DYRRRFCRPSRAPDINTNQNQNMLEILQ
NCFEEKSKA-------SFSDLYSTPKMKTSCTK-SPSK-----DCQKSHPGS----FPIS
SRKKE-A-----------SLQGILEPSEAASR----------------------------
------------SA

ENSGT00390000016737_Linker_0_1 (195, 366)

DEEFYISVGSPTVLLHEKPSES--Q------------NAVS-STQK
RETYTFGNSEHTLSSSTEISLKTKKRLNFEDKYILKKVERETNKSEVEDKVSGQ-QERRR
S---ETSPKRVQDTEYEVQSQAKKSFSKLFLETVKRKGES--SPIVRHAAMAPSHLSP--
--PND

PF15620 // ENSGT00390000016737_Domain_1 (366, 739)

TKLLEDEFIIDKSDRSFASQSWITIPRKSRPLKQ-HTVSS-VESTAVL-QCEK-P
-----------------------RE-HQSVLPVTLTSDKHLHK-----------------
-------------------AHPEEKSEPLNEKKPSTSCTLTDELESNCRSIK--MYSEKA
EKPSGN--KRTTKKKQKR-KLKTSVVEEQPDTGQTKDEN--MSHI-AQDKLPR--NSDRI
TEG---CEEMRNGH----NAKKEMP-PVENMKTKCST------KKDKKESR-KK------
-HFSSES--------------------KRKKLV--PEEM-TLTITRSHRVSRRPSDWWMI
NAEESPVHSNS--VRNDI

ENSGT00390000016737_Linker_1_2 (739, 1136)

LVYHNSRQKP-SK-------KIVKKTILSKRQKS-TQRSSRV
Q-K---FLNVKGSGS---II-GHD-EVSTCPQN---EPL---------ESDKIDLTKKKN
LDCS--RPVTK---C--------------RLCM-STE-NVHLKAQTS-EDTCKT-PGESN
-------------------LDSGESKTSVLEESGPSRLN-NYLMSRKNNSAVNNE-VQES
VGKLLHTHI-----------------Y---IFICHLFTVLPSNTPNVRRTKRIRSKPLEY
WRGERVDYQETPS-GLVIGGILSPETVISKR-KAKGNVGKVNKIDNRK-RICLDNIER--
---MLNLDIPLGDPFQPTQVKDPETREIIL-MDLIRPRDTYQFFVE-----HGEL

PF11699 // ENSGT00390000016737_Domain_2 (1136, 1219)

KVYKT
LDTPLFSTGKLVLGPYEEKGKQHVGEDILVFYVNVGDLLCTLHETPYMITTGDSFYVPSG
NYYNIKNLLNEESILLFTQIKR------------------------

----------MASFHLDHLKN------YH------RRYCRPSRAPNIHTKEGQNVLEILQ
DCFEDQSKASFLDDFT-ESLTSSTQKKKANYSQ-SSSK-----KCPESHSKP----VPVS
SRTGE-A-----------ALQAPAEPSEAAGGAVQANEV---------------------
---------H

PF15622 // ENSGT00390000016737_Domain_0 (191, 356)

HG-VSDELDLCVGSPVVLLDANANTL--Q------------KAASPAGQK
RVASVSRSPVDRQASNKNISFKTRKRLNFEDKVTSSTAETENSVLQVEDNLSKGQ-EGTS
S---EITQK-RDDLSSDVQSRSKKNFSELFLETVKRKSKS--SSVVRHTAAVPSS

ENSGT00390000016737_Linker_0_1 (356, 366)

PPP--
--PSD

PF15620 // ENSGT00390000016737_Domain_1 (366, 740)

MKLLEDEFIIDRSDRSFSSRLWVMIPSKDRHLSA-HKPSP--ENTALL-QGKK-S
-----------------------REKSHSLSAVTFARNTQSDK-----------------
-------------------THPIEEAQLSVEENL--GTTCTDELENDCRSPENKMQSETA
KTPPAW--ERTTKQNQRR-VSKPKAAE-ELRKGQSSCENSNVSNT-GQDKLQI--NSKRN
MKD---CEEVRNEP----TPKKHKP-ALENKKKTNST------QTNKEKSG-KK------
-FFSGGS--------------------KN-KFV--PKKV-TLTSRRSCRISQRPSDWWRV
KSDESSVDRNP-SKENNSP

ENSGT00390000016737_Linker_1_2 (740, 1136)

VVYPNKKKQ-TK-RNHVSKRARKKPGPSKRQKT--EMSPRV
Q-K---SLNVKDSGG---TVSGHD-DTS-RSQR---KPL---------KNIEADPTQ-KS
LAISRP--KRGCKYR--------------NNVM-TSP-NVHLKSHTE-EYTSKT-QMESA
-------------------SNSEMSKRSVWEESGPSRFK-NYEMPGSSNSEMGDEQDQKS
L---------------HFTTRSFNMVP---DKKLHHKLVLPSNSPNVRRSNRIRLKPLEY
WRGERVDYQESSSGQ-LVLEIISPASVPTKI-KAQRNLGKVNKKVTKK-QTHLNSHEKA-
-KMELPLDMRLGDPFQATLAKDPETAELVP-MELIRPRDTYRFFVE-----QHGL

PF11699 // ENSGT00390000016737_Domain_2 (1136, 1219)

KVFKT
LDTIYFSTGKLVLGPYEEKGKQHVGQDILVFYVNFGELLCTLHETPYKITTGDSFYVPSG
NHYNIKNLLNVESSLLFTQIKR------------------------

----------MAASGL

PF15622 // ENSGT00390000016737_Domain_0 (17, 358)

DHLKN-----------GYRRRFCRPSRARDINTEQGQNVLEILQ
DCFEEKSLANDFSTNSTKSVPNSTRKIKDTCTQ-SPSK-----ECQKSHPKS----VPVS
SRKKE-A-----------SLQFVVEPSEATNRSVQAHEVHQKILAT-DVSSKNTPDSKKK
SS--RNTNDHHSKADEEFYLSVGSPSVLLDAKTSAS--Q------------NVIPSGAQK
RETYTFENSVNILPSSTEVSVKTKKRLNFDDKVVLKKIEIDNKVSDEEDKTSEG-QERKP
S---GSSQNRIRDSEYEIQRQAKKSFSALFLETVKRKSES--SPIVRHAATAPPHSC

ENSGT00390000016737_Linker_0_1 (358, 366)

P--
--PAD

PF15620 // ENSGT00390000016737_Domain_1 (366, 740)

MKLVEDEFIIDESDQSFASRSWITIPRKAGPLKQ-RTISP-AESTALL-QGRK-S
-----------------------REKHHNLLPKTLANDKHSHK-----------------
-------------------PHPVETSQPSDKTVLDTSYALTGETENNYRSTKYEMYSKNA
EKPSRS--KRTIKQKQRR-KFMAKPAEEQLDVGQSKDENIHTSHI-TQDEFQR--NSDRN
MEE---REEMGNDC----VSKKQMP-PVGSKK--SST------RKDKEGSK-KK------
-RFSSES--------------------KN-KLV--PEEV-TSTVTRSRRISRRPSDWWVV
KSEESPVYSNS-SIRNELP

ENSGT00390000016737_Linker_1_2 (740, 1136)

VHHNSRQKS-AKKTNQSSKNIGKKTIPLKRQKTATKGNQRV
Q-K---LLNAEGSGG---TI-GHD-EISRRSLS---EPL---------ESDEADLAKKKN
LDCSRS--TGSSKNE--------------DDIM-TAQ-NVPLKPQTS-GYTCNI-PTESN
-------------------LDSGEHKTSVLEESGPSRLNNNYLMSGKN--DVDDEEVHGS
S--------------DDS--KPSKVIP---KNRIHRKLVLPSNTPNVRRTKRTRLKPLEY
WRGERIDYQGRPSGGFVIGGILSPDTISSKR-KAKENTGKVDKKSNKK-RICLDNDERKT
-NLMVNLGIPLGDPLQPTRVKDPETREIIL-MDLIRPQDTYQFFVK-----HGEL

PF11699 // ENSGT00390000016737_Domain_2 (1136, 1219)

KVYKT
LDTPFFSTGKLILGPQEEKGKQHVGQDILVFYVNFGDLLCTLHETPYVISTGDSFYVPSG
NYYNIKNLRNEESVLLFTQIKR------------------------

----------MASSDLDHLKI-----------SYRTRFCCTSRLPVTDLWQGQNLLENIQ
DCFEEKSYDTGFSTNPGSPTLCSTPCKLRNDSYSSPNK-----ECQISPSKT----DCVS
SVKKKAKTSVLS------HQTIMLQ-SQG-NNSVLPPEIPQKLSQADLVDLKNTPNLKYA
SSGAEEFNKIPNEVVEEFYLTVGSPGLLAKETEI-LPLPK-----------QATPTAH-D
RWNHKFGNSVNQQPSLPTSSLKTKKSLNYEDITVWSAVK----TAEKDIKLSERRQKRIQ
S---ES-EKGSQDTKQKIQQRAKTNFSTLLLEAAKGNCRN--SSVHRHVSPPQTYSPSP-
-LPNDLESSNDEFIIDESD-CSASQSWILIPNKNSKSVKPGKTDP-VKSSQDS-ERKNSS
------------------------------------SDKHLNTEKEISN--IVSEERTSK
SIKH--------------KARAVEKSQPSKRKK---LDSLSNEMGSTSKSTRHKIYSEKS
EQFLEN--KGAILRKCQKKDYKPQVSVKHHGTEQTKKKRSNMSQR-NQDKLHRESD--RI
LGQ----QKERA---ESCHSAEQILSAD----------------GHLKKTSNKNEQMPKK
RESLLKQ---------------------------NKSQ--DFTVTRSQRISKRPSTWWVV
TTEQSKYYH--F-IMNKLPVNHKKASRPSKETKKISVKTLGKGTIPLKRQKSSINAKSKA
----------------ASIPNKRKGRRLSYSSDENCDMVHMIPNIDEQEGSLKETPKVA-
--CSS----------------T--AEPSEECIG-AAQ-NVNLTPTILTGD-----SKIS-
-------------------------VTSAMEESGPTRLRNNVLTSRFNKIS-GDEQECGT
N--------------TIQEVKLELLRKNLVENKK----LLIKGNLPVRRTTRIKIKPLEY
WRGERFDYENMLLDGFTVSGTISNDRVSPKQ-KSNRKRERVNT------DSCEDEQK---
KKAIASLDISLGDPSKPTCVFDPGREQMVF-KELVKIKGTHEFCVQ-----DDTL

PF11699 // ENSGT00390000016737_Domain_2 (1136, 1219)

KMFKI
LNTSMFATGTLILEPFKEKGKQYVCSDTVVFFVVSGNLLCTLHETNYNLNSGDTFYVPSG
NFYNIKNLIDERSILLFTQIKTERPEK-------------------

---------MASSFHL

PF15622 // ENSGT00390000016737_Domain_0 (17, 358)

DHLKNY------------RRRFCRPSRAPNINTRQGQNVLEILQ
DCFEEQNS--------TESLLCTTPKAKDNCNQ-SAGK-----EASHS--ES----VPVS
S-RKK-G-----------TLKVAAEPSEAACGSVQANEVHQKILAT-DNVSKSTVDSNSM
SS--EKTNGHHRATNDNFCLSRGSPVVLLDAKTSEL--Q------------NVISSLGQR
RVTSVLRNSVDKKSSNTDISLKTRKRLNFEDKSILNQAEIVNSVLEVEDNISEGQ-EEIS
S---GTFQERGQDLSYEIQQRSKKSFSALYLEAVKRKNES--SSI-VRHTAALPLSS

ENSGT00390000016737_Linker_0_1 (358, 367)

P--
--PNEA

PF15620 // ENSGT00390000016737_Domain_1 (367, 740)

KLLEDEFIIDESDRNFASQPLVTIPRKGRHLRH-NLPSS--ENIVTP-EDKK-L
-----------------------REKP-----TTVISDSQPQK-----------------
-------------------SPSIGKSQPPVENIL--GTSCTDELESDCRSTENKMHSENA
KKTSGC--KRTVRQKQRR-VSKPNVVEEKLNVGQGKKGKRNMSNI-GQDKLQV--NSKRT
KKD---CEDSRNEP----TPKKQMP-PIENKKNQHST------PKDRKKSG-KK------
-CFSGES--------------------RN-TFV--PEEV-SVSVRRSHRVSQHPSEWWLV
KPEKGSVDRSS-SRANESL

ENSGT00390000016737_Linker_1_2 (740, 1136)

VVHRNRKKR-TK-KNQLSKNAGKKPLPSKRQKT--ENSSRV
Q-K---SLNVKGSRE---SVSSHD-EIS-GNQS---KPL---------ENNEADLTLKRS
LNISGP--TGGSKHQ--------------SSIM-TSQ-NIHLKSHTG-KYTT-R-SMESN
-------------------SGSGEPKNSIWEESGPSRFK-DCVLSGSNNFGVSDEKEQES
L---------------DLRISTSNELP---DTNIHHKLVLPSNSPNVRRTKRIRLKPLEY
WRGERIDYQERPSGR-IVIGIVSPAPVSPKR-KAKGNLGKVTKKANKK-WIRPENHEKD-
-RLVVNLDIPLGDPFQATLAKDPETREIIP-MDLIRPRDTYQFFVE-----QHGL

PF11699 // ENSGT00390000016737_Domain_2 (1136, 1219)

KVFKT
LDTAFFSTGKLVLGPYEEKGKQHVGQDILVFYVNFGELLCTLHETPYMITTGDSFYVPSG
NHYNIKNLLNVESCLLFTQIKR------------------------