Query Results 

---------MEVSPLQPVNENMQVNKIKKNEDAKKRLSVERIYQKKT-QLEHILL-----
---------RP-D-T-YI--GSVELVTQQMWVYDEDVGINYREVTFV

PF02518 // ENSGT00390000016222_1_Domain_0 (108, 255)

PGLYKIFDEILVN
AADNKQRDPKMSCIRVTIDPENNLISIWNNGKGIPVVEHKVEKMYVPALIFGQLLTSSNY
DDDEKKVTGGRNGYGAKLCNIFSTKFTVETASREYKKMFKQ--TWMDNMGRAGEMELKPF
NGEDYTCITFQPDLSKFKMQSLDKDIVALMVRRAYDIAGSTKDVKVFLNGNKLP------
--VKGFRSYVDMYLKDKLDETGNSLKVIHEQVNHRWEVCLTMSEKGFQQISFVNSIATS-
----------------------------------KGGRHVDYVADQIVTKLVDVVKKKNK
GGVAVKAHQVKNHMWIFVNALIENPTFDSQTKENMTL-------------------Q-P-
-K--S-F--G-S--T--C-Q--L-S--E--K------------------FIKA-------
-----------------AIGC-GIV-ES-ILN-WVK-FK-AQV-QLN-KKC-SAV-KHN-
RIK-GIP-KLD-DAND-AGGRNSTE--C-TL

PF01751 // ENSGT00390000016222_1_Domain_3 (632, 769)

-ILT-EGD-SAK-TL-AVS-GL-GVV-GR
-DKY-GVF-PL-RGK-ILN-VR-EAS-HKQ-IME-NAE-INN-IIK-IVG-LQY-KKN-Y
ED-EDS-LKT-LRY-GKI-MI-MTD-QDQ-DGS-HIK-GL-LI-NFI-

ENSGT00390000016222_1_Linker_3_5 (769, 790)

HH-NWP-SL-LR
H-RF-LEE-

PF16898 // ENSGT00390000016222_1_Domain_5 (790, 962)

FI-TPIV-KVS-KNK-QEMAFYSL---PEF-EEWKSST-------PNHKKW
KVKYYKG------------------LGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAIS
LAF-SKKQIDDRKEWLTNFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNS
DNERSIPSMVDGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTII
N--LAQNFVGSNNLNLLQPIGQFGTRLHGGKDSASPRYIFTMLSSLARLLFPPKDDHTLK
FLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWSCKIPNFDVREIVNNIRRLMDGEEPLP
MLPSYKNFKGTIEELAPNQYVISGEVAILNSTTIEISELPVRTWTQTYKEQVLEPMLNGT
EKTPPLITDYREYHTD-TTVKFVVKMTEEKLAEAERVGLHKVFKLQTSLTCNSMVLFDHV
GCLKKYDTVLDILRDFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIE
NKPKKELIKVLIQRGY-----D---SDPVKAWKEAQQKVPDE--EENEESDNEKETEKSD
SVTDSGPTFNYLLD-MPLWYLTKEKKDELCRLRNEKEQELDTLKRKSPSDLWKEDLATFI
EELEAVEAKEKQDEQVGLPGKG---------GKAKGKKT--QM-AEVLPSPRGQRVIPRI
TIEMKAE----------NENTEGSP-------QEDGVELEGLKQRLEKK--QKRE---PG
TKTKKQTTLPFKPIKKGKKRNPWSDSESDRSS-DESNFD---VPPRETEPRRAATKTKFT
VDLDSDEDFSDFDEK-TDD---EDFVPSD-A-----SPPKTKTSPKLSNK-ELKPQK---
SVVSDLEAD--D---------AK--DSVPLSSSPPAT---HFPDETEIT-NPVPKKNVTV
KKTA-AKSQ-------------SSTSTTGAKK

PF08070 // ENSGT00390000016222_1_Domain_9 (1773, 1882)

RAAPKG-TK-----RDPALNSGVS-QKP
DPAKTK-NRRKRKPSTSDDSDSNFEKIVSKAVTSKKSKGES-DDFHMD------FDSAVA
PRAKSVR-------AKKPIKYLEESDEDDLF-------

---------MEVSPLQPVNENMQINKIKKNEDAKKRLSVERIYQKKT-QLEHILL-----
---------RP-D-T-YI--GSVELVTQQMWVYDEDVGINYREVTFV

PF02518 // ENSGT00390000016222_1_Domain_0 (108, 255)

PGLYKIFDEILVN
AADNKQRDPKMSCIRVTIDPENNIISIWNNGKGIPVVEHKVEKMYVPALIFGQLLTSSNY
DDDEKKVTGGRNGYGAKLCNIFSTKFTVETASREYKKMFKQ--TWMDNMGRAGEMELKPF
NGEDYTCITFQPDLSKFKMQSLDKDIVALMVRRAYDIAGSTKDVKVFLNGNKLP------
--VKGFRSYVDMYLKDKLDETGNSLKVIHEQVNHRWEVCLTMSEKGFQQISFVNSIATS-
----------------------------------KGGRHVDYVADQIVTKLVDVVKKKNK
GGVAVKAHQVKNHMWIFVNALIENPTFDSQTKENMTL-------------------Q-P-
-K--S-F--G-S--T--C-Q--L-S--E--K------------------FIKA-------
-----------------AIGC-GIV-ES-ILN-WVK-FK-AQV-QLN-KKC-SAV-KHN-
RIK-GIP-KLD-DAND-AGGRNSTE--C-TL

PF01751 // ENSGT00390000016222_1_Domain_3 (632, 769)

-ILT-EGD-SAK-TL-AVS-GL-GVV-GR
-DKY-GVF-PL-RGK-ILN-VR-EAS-HKQ-IME-NAE-INN-IIK-IVG-LQY-KKN-Y
ED-EDS-LKT-LRY-GKI-MI-MTD-QDQ-DGS-HIK-GL-LI-NFI-

ENSGT00390000016222_1_Linker_3_5 (769, 790)

HH-NWP-SL-LR
H-RF-LEE-

PF16898 // ENSGT00390000016222_1_Domain_5 (790, 962)

FI-TPIV-KVS-KNK-QEIAFYSL---PEF-EEWKSST-------PNHKKW
KVKYYKG------------------LGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAIS
LAF-SKKQTDDRKEWLTNFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNS
DNERSIPSMVDGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTII
N--LAQNFVGSNNLNLLQPIGQFGTRLHGGKDSASPRYIFTMLSSLARLLFPPKDDHTLK
FLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWSCKIPNFDVREIVNNIRRLMDGEEPLP
MVSILCVL-----------------------------RALTFPWVSTYKEQVLEPMMNGT
EKTPPLITDYREYHTD-TTVKFVVKMTEEKLAEAERVGLHKVFKLQTSLTCNSMVLFDHV
GCLKKYDTVLDILRDFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIE
NKPKKELIKVLIQRGY-----D---SDPVKAWKEAQQKVPDE--EENEESDNEKETGKSD
SVTDSGPTFNYLLD-MPLWYLTKEKKDELCRLRNEKEQELDTLKRKSPSDLWKEDLATFV
EELEAVEAKEKQDEQVGLPGKG---------GKAKGKKT--QM-TEVLPSPCGQRVIPRI
TIEMKAEAEKKNKKKIKNENTEGSP-------QEDGMELEGLKQRLEKK--QKRE---PG
TKTKKQTTLPFKPIKKGKKRNPWSDSESDRSS-DESNFD---VPPRETEPRRAATKTKFT
MDLDSDEDFSDFDEK-TDD---EDFVPSG-A-----SPPKTKTSLKLTNK-ELKPQK---
STMSDLEAD--D---------AK--DSVPLSSSPPAT---HFPDETEIT-NPVPKKNVTA
KKTA-AKSQ-------------SSTSTTGAKK

PF08070 // ENSGT00390000016222_1_Domain_9 (1773, 1882)

RAAPKG-TK-----RDPALNSGVS-QKP
DPAKTK-NRRKRKASTSDDSDSNFEKIVSKAVTSKKSKGES-DDFHMD------FDSAVA
PRAKSVR-------AKKPIKYLEESDEDDLF-------

-----MELSQPSSPLRPVKENVLVG---KADGP-KKLTVEHIYQKKT-QLEHILL-----
---------RP---DTYI--GSVELVTQQMWVFDEGVGLNCRDVTFV

PF02518 // ENSGT00390000016222_1_Domain_0 (108, 254)

PGLYKIFDEILVN
AADNKQRDKNMSCIKVTIDVENNTISVWNNGKGIPVVEHKVEKVYVPAMIFGQLLTSSNY
DDNEKKVTGGRNGYGAKLCNIFSTKFTVETGCREYKKLFKQ--TWTDNMGKAGEMKLKYF
DGDDYTCVTFQPD

ENSGT00390000016222_1_Linker_0_1 (254, 305)

LSKFKMTVLDKDIVALMSRRAYDIAGSTKDVKVFLNGQRLP------
--VK

PF00204 // ENSGT00390000016222_1_Domain_1 (305, 590)

GFRSYVDLYLKDKVDETGNALKVIHEEVNSRWEVCLTLSEKGFQQVSFVNSIATT-
----------------------------------KGGRHVDYVADQLVTKLIDVVKKKNK
NGVGVKPFQVKNHMWIFVNALIENPTFDSQTKENMTLQSKNFG-----------------
---------------STCKL--------------------------SEKFI-----KG--
----------------AV-GC-GIV-ES-ILN-WVK-FK-AQN-QLN-KKC-SAV-KHS-
KIK-GVP-KLD-DAND-AGN-KNS-LDC-TL-ILT-EGD-SAK-TL-AVS-GL-GVV-GR
-DKY-GVF-PL-RGK-ILN-VR-EAS-HKQ-IME-NAE-INN-IIK-IVG-LQY-KKN-Y
ED-QES-LKS-LRY-GKI-MI-MTD-QDQ-DGS-HIK-GL-LI-NFI-HH-NWP-SL-LR
H-NF-LEE-FIT-PII-KAS-KNK-EEI-AF-YSI-PEF-EEW-KAS-T-----QNYNSW
KIKYYKG------------------LGTSTSKEAKEYFADMAKHRIGFKYSGPEDDAAIT
LAF-SKKKIEERKEWLTNFMEDRRQRKLHGLPEEYLYGKNTDYLTYNDFINKELVLFSNS
DNERSIPSLVDGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEAALMMTII
N--LAQNFVGSNNLNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLARLVFPPMDDNILR
FLYDDNQRVEPEWYMPIIPMVLVNGAEGIGTGWACKIPNFDIREVVNNIRRLMDGEEPLP
MLPSYKNFKGTIDELGPNQYVISGEVSILDSTTIEITELPVRTWTQTYKEQVLEPMLNGT
EKTPPLITDYKEYHTD-TTVRFVVKMTEDKLAEAEAVGLHKVFKLQTSLTCNSMVLFDHV
GFLKKYDSPQDILKEFFELRLRYYNLRKEWLIGMLGAESAKLSNQARFILEKIDGKIVIE
NKPKKELIQVLIQRGY-----E---SDPVKAWKEAQNKDEEE--GEE--EE-----SDKE
SSSASGPDFNYLLN-MPLWYLTKEKKDELCKQRDNKEKELETLKRKSPSDLWKEDLAAFI
EELDVVEAKQAQDESAGIVGKPLKVKGG----KAKVKKI--QL-AEVMPSPHGIRVVPRI
TAEMKAEAEKKTKKKVKSEKNEFDENQDEN--TSGEKESVGLKKRLMQKLKTEQ-----G
AK--RQATLPFKPLKKTKKRNPWSDSGSDS-ESD-FEAPP----QRERVVRQAAAKVKPM
VISDSN--HSSSDEDSEFQGDSEGNSESDTN-SKKKAPPKPKPAPKETTEKAAKAPKQK-
AAPSAVPGEFQDV----P------E----DKVSQA-PAAPSVPAPS--T-KAVPKKTTAA
K--KAGAT--------K--DNQPSIMDVLAKKKAAPKPKPAA-KEGPLHGE--------

PF08070 // ENSGT00390000016222_1_Domain_9 (1800, 1883)

G
DNAKGRKAVKRQPSSLNSDSDSDFGSKPAKSVASKKSKMQED-TFTID---SGDESPVPQ
PRARPGR-------AKKPVQYLEE----SSEDDMF---

----------QTSPLHPVNENMQVNKAKKNEDAKKRLSIERIYQKKT-QLEHILL-----
---------RP-D-T-YI--GSVESVTQQMWVYDEDIGMNYREV

PF02518 // ENSGT00390000016222_1_Domain_0 (105, 255)

TFVPGLYKIFDEILVN
AADNKQRDPKMSCIRVIIDPENNLISIWNNGKGIPVVEHKVEKMYVPALIFGQLLTSSNY
DDEEKKVTGGRNGYGAKLCNIFSTKFTVETASREYKKMFKQ--TWMNNMGKAGEMELKPF
NGEDYTCITFHPDLSKFKMQSLDKDIVALMVRRAYDIAGSTKDVKVFLNGSKLP------
--VKGFRSYVDMYLKDKVDETGNPLKIIHEQVNHRWEVCLTMSEKGFQQISFVNSIATS-
----------------------------------KGGRHVDYVADQIVTKLVDVVKKKNK
GGVAVKAHQTRSCSSVLG------------------------------------------
----------------------Q-F--F--E------------------LFFL-------
-----------------ATGC-GIV-ES-ILN-WVK-FK-AQI-QLN-KKC-SAV-KHN-
RIK-GIP-KLD-DAND-AGGRNSTE--C-TL-ILT-EGD-SAK-TL-AVS-GL-GVV-GR
-DKY-GVF-PL-RGK-ILN-VR-EAS-HKQ-IME-NAE-INN-IIK-IVG-LQY-KKN-Y
ED-EDS-LKT-LRY-GKI-MI-MTD-QDQ-DGS-HIK-GL-LI-NFI-HH-NWP-SL-LR
H-RF-LEE-FI-TPIV-KVS-KNK-QEMAFYSL---PEF-EEWKSST-------PNHKKW
KVKYYKG------------------LGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAIS
LAF-SKKQIDDRKEWLTHFMEDRRQRKLLGLPE-YLYGQTTTYLTYNDFXXXXXXXXXXX
XXXXXXXXXXXX

PF00521 // ENSGT00390000016222_1_Domain_6 (973, 1448)

LKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTII
N--LAQNFVGSNNLNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLARLLFPPKDDHTLK
FLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWSCKIPNFDVREVVNNIRLLMDGAEPLP
MLPSYKNFKGTIEELAPNQYVISGEVAILNSTTIEISELPIRTWTQTYKEQVLEPMLNGT
EKTPPLITDYREYHTD-TTVKFVVKMTEEKLAEAERAGLHKVFKLQTSLTCNSMVLFDHV
GCLKKYDTALDILRDFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIE
NKPKKELIKVLIQRGY-----D---SDPVKAWKEAQQKVPDE--EENEESDNEKETEKSD
SVADSGPTFNYLLD-MPLWYLTKEKKDELCKLRNEKEQELETLKRKSPSDLWKEDLAAFI
EELEAVE

ENSGT00390000016222_1_Linker_6_9 (1448, 1773)

AKEKQDEQIGLPGKG---------GKAKGKKT--QM-AEVLPSPCGKRVIPQV
TIEMK------------NENTEGNP-------QEDGMEVESLKQRLEKK--QKRE---PG
TKTKKQTTLPFKPVKKAKKRNPWSDSESDMSS-NESNFD---VPPREKEPRRAAAKTKFT
VDLDSDEDGSDFDEKT-QD---EDFVPSDA------SSLKTKTSPKHTNK-ELKP-----
QR---SAKSDFDA--------DDAEDNVAPSPSSPAA---DFPAVTETI-NPVSKKNVTV
KKTA-AKSQ-------------SSTSTTGAKK

PF08070 // ENSGT00390000016222_1_Domain_9 (1773, 1883)

RAAPKG-TK-----KDPDMDSDVS-KKP
NPPKTK-GRRKRKPSTSDDSDSNFEKMISKAVTSKKSKEES-DEFHVD------LDSAVA
SRAKSGR-------TKKPIKYLEESDEDDLF-------

---------MDVSPLQPINENMQINKAKKNEDAKKRLSVERIYQKKT-QLEHILL-----
---------RP-D-T-YI--GSVELVTQQMWVYDEDVGINYREVTFV

PF02518 // ENSGT00390000016222_1_Domain_0 (108, 254)

PGLYKIFDEILVN
AADNKQRDPKMSCIRVTIDPENNLISIWNNGKGIPVVEHKVEKMYVPALIFGQLLTSSNY
DDDEKKVTGGRNGYGAKLCNIFSTKFTVETASREYKKMFKQAITWMDNMGRAGEMELKPF
NGEDYTCITFHPD

ENSGT00390000016222_1_Linker_0_1 (254, 305)

LSKFKMQSLDKDIVALMVRRAYDIAGSTKDVKVFLNGNKLP------
--VK

PF00204 // ENSGT00390000016222_1_Domain_1 (305, 590)

GFRSYVDMYLKDKVDETGNPLKIIHEQVNHRWEVCLTMSEKGFQQISFVNSIATS-
----------------------------------KGGRHVDYVADQIVTKLVDVVKKKNK
GGVAVKAHQVKNHMWIFVNALIENPTFDSQTKENMTL-------------------Q-A-
-K--N-F--G-S--T--C-Q--L-S--E--K------------------FIKA-------
-----------------AIGC-GIV-ES-ILN-WVK-FK-AQV-QLN-KKC-SAV-KHN-
RIK-GIP-KLD-DAND-AGGRNSTE--C-TL-ILT-EGD-SAK-TL-AVS-GL-GVV-GR
-DKY-GVF-PL-RGK-ILN-VR-EAS-HKQ-IME-NAE-INN-IIK-IVG-LQY-KKN-Y
ED-EDS-LKT-LRY-GKI-MI-MTD-QDQ-DGS-HIK-GL-LI-NFI-HH-NWP-SL-LR
H-RF-LEE-FI-TPIV-KVS-KNK-QEMAFYSL---PEF-EEWKSST-------PNHKKW
KVKYYKG------------------LGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAIS
LAF-SKKQIDDRKEWLTHFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNS
DNERSIPSMVDGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEVNTQSMMF
PESIIAEIPAKLKLYVCSPLAHRNCSNIVKSVSASKAKVMFVYIPLARLLFPPKDDHTLK
FLYDDNQRVEPEWYIPIIPMVLVNGAEGIGTGWSCKIPNFDVREIVNNIRRLMDGEEPLP
MLPSYKNFKGTIEELAPNQYVISGEVAILNSTTIEISELPIRTWTQTYKEQVLEPMLNGT
EKTPPLITDYREYHTD-TTVKFVVKMTEEKLAEAERVGLHKVFKLQTSLTCNSMVLFDHV
GCLKKYDTVLDILRDFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIE
NKPKKELIKVLIQRGY-----D---SDPVKAWKEAQQKVPDE--EENEESDSEKETEKSG
SVTDSGPTFNYLLD-MPLWYLTKEKKDELCKLRNEKEQELETLKRKSPSDLWKEDLAAFI
EELEAVEAKEKQDEQVGLPGKG---------GKAKGKKT--QR-AEVLPSPSGKRVIPRV
TIEMKAEAEKKFKKKIKSENTEGSP-------QEDGTEVEGLKQRLEKK--QKRQ---PD
TKTKKQITLPFKPVK-GKKRNPWSDSESDMSS-NESNFD---VPPRETEPRRAATKTKFT
MDLDSDEPFSDFDEKT-QE---EDFVPSDS------SLPKTKSSLKHANK-ELKTQK---
---SAVSVTDLDA--------DDAKDSVPLSPSSSAA---DFPAETEII-NPISKKKVTV
KKIA-AKSQ-------------SSTSTTGTKK

PF08070 // ENSGT00390000016222_1_Domain_9 (1773, 1883)

PAP-K-RVK-----KDPGLNSDVS-QKP
DMPKTK-NPRKRKPSTSDDSDSNFEKMISKAVTNKKSK-EN-DDFHLD------LDSTVA
PRAKSGR-------ARKPIKYLEESDEDDLF-------

---------MELSPLQPVNENMLLNK-KKNEDGKKRLSVERIYQKKT-QLEHILL-----
---------RP-D-T-YI--GSVELVTQQMWVYDEDVGINYREVTFV

PF02518 // ENSGT00390000016222_1_Domain_0 (108, 255)

PGLYKIFDEILVN
AADNKQRDPKMSCIRVTIDAKNNLISIWNNGKGIPVVEHKVEKMYVPALIFGQLLTSSNY
DDDEKKVTGGRNGYGAKLCNIFSTKFTVETASREYKKMFKQ--TWMDNMGRAGDMELKPF
SGEDYTCITFQPDLSKFKMQSLDKDIVALMVRRAYDIAGSTKDVKVFLNGNRLP------
--VKGFRSYVDMYLKDKVDETGNALKVVHEQVNPRWEVCLTMSEKGFQQISFVNSIATS-
----------------------------------KGGRHVDYVADQIVSKLVDVVKKKNK
GGVAVKAHQVKNHMWIFVNALIENPTFDSQTKENMTL-------------------Q-A-
-K--S-F--G-S--T--C-Q--L-S--E--K------------------FIKA-------
-----------------AIGC-GIV-ES-ILN-WVK-FK-AQI-QLN-KKC-SAV-KHN-
RIK-GIP-KLD-DAND-AGSRNSAE--C-TL

PF01751 // ENSGT00390000016222_1_Domain_3 (632, 769)

-ILT-EGD-SAK-TL-AVS-GL-GVV-GR
-DKY-GVF-PL-RGK-ILN-VR-EAS-HKQ-IME-NAE-INN-IIK-IVG-LQY-KKN-Y
ED-EDS-LKT-LRY-GKI-MI-MTD-QDQ-DGS-HIK-GL-LI-NFI-

ENSGT00390000016222_1_Linker_3_5 (769, 790)

HH-NWP-SL-LR
H-RF-LEE-

PF16898 // ENSGT00390000016222_1_Domain_5 (790, 962)

FI-TPIV-KVS-KNK-QEIAFYSL---PEF-EEWKSAN-------PNHKKW
KVKYYKG------------------LGTSTSKEAKEYFANMKRHRIQFKYSGPEDDAAIS
LAF-SKKQVDDRKEWLTNFMEDRRQRKLLGLPEDYLYGQTTMYLTYNDFINKELILFSNS
DNERSIPSMVDGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTII
N--LAQNFVGSNNLNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLARLLFPSKDDHTLR
FLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWSCKIPNFDVREVVNNIRRLLDGEEPLP
MLPSYKNYKGTIEELASNQYVINGEVAILNSTTIEITELPIRTWTQTYKEQVLEPMLNGT
EKTPPLITDYREYHTD-TTVKFVIKMTEEKLAEAERVGLHKVFKLQTSLTCNSMVLFDHV
GCLKKYDTVLDILRDFFELRLKYYGLRKEWLLGMLGAESSKLNNQARFILEKIDGKIVIE
NKPKKELIKVLIQRGY-----D---SDPVKAWKEAQQKVPEE--EENEENEES-ESESSS
PAAESGPTFNYLLD-MPLWYLTKEKKDELCKQRDEKEQELNTLKKKTPSDLWKEDLAAFV
EELEVVEAKEKQDEQVGLPGKG---------VKAKGKKA--QI-SEVLPSPVGKRVIPQV
TMEMRAEAEKKIRRKIKSENVEGTP-------AEDGAEPGGLRQRLEKR--QKRE---PG
TRAKKQTTLPFKPIKKGKKKNPWSDSESDMSS-NESNFD---VPPREKEPRIAATKAKFT
ADLDSDDDFSGLDEKD-ED---EDFFPLD-D-----TPPKTKMPPKNTKK-ALKPQKSST
S-V------DLE---------SDGKDSVPASPGASA---ADVPAETEPS-KPSSKQTVGV
KRTITKGQS-------------LTS-TAGTK

PF08070 // ENSGT00390000016222_1_Domain_9 (1772, 1882)

KRAVPKE-TK-----SDSALNAHVS-KKP
APAKAKN-SRKRKPSSSDSSDSEFEKAISKGATSKKPKGEE-RDFHVD------LDDTVA
PRAKSGR-------ARKPIKYLEESDDDL----F----

----------------PVNEHMQMNKIKKNEDAKKRLSIERIYQKKT-QLEHILL-----
---------RP---DTYI--GSVELLTQQMWVYDEDIGINYREITFV

PF02518 // ENSGT00390000016222_1_Domain_0 (108, 255)

PGLYKIFDEILVN
AADNKQRDPKMSCIRVTIDPENNLISVWNNGKGIPVVEHKVEKVYVPALIFGQLLTSSNY
DDDERKVTGGRNGYGAKLCNIFSTRFTVETASKDYKKMFKQ--TWMDNMGRAGEMELKPF
SGEDYTCITFQPDL

ENSGT00390000016222_1_Linker_0_1 (255, 305)

SKFKMERLDKDIVALMVRRAYDIAGSTKDVKVFLNGNNISLAKDTR
KFVT

PF00204 // ENSGT00390000016222_1_Domain_1 (305, 590)

GFRSYVDMYLKDKLDETGNPLKVIHEQVNQRWEVCLTMSEKGFQQISFVNSIATS-
----------------------------------KGGRHVDYVADQIVTKLMDVVKKKNK
GGIAVKAHQVKNHMWIFVNALIENPTFDSQTKENMTLQVKS-------------------
------F--G-----STCQL--------------------------SEKFIKA-------
-----------------AIGC-GIV-ES-ILN-WVK-FK-AQV-QLN-KKC-SAV-KHN-
KIK-GIP-KLD-DAND-AGSRNSTE--C-TL-ILT-EGD-SAK-TL-AVS-GL-GVV-GR
-DKY-GVF-PL-RGK-MLN-VR-EAS-HKQ-IME-NAE-INN-IIK-IVG-LQY-KKN-Y
AD-EDS-LKT-LRY-GKI-MI-MTD-Q---------------------------------
-------E-FI-SPIV-KVS-KNK-QE---------------------------------
------------------------------------------------------------
--------------------------------LDYLYGQTTTYLTYNDFINKELILFSNS
DNERSIPSMVDGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTII
N--LAQNFVGSNNVNLLQPIAQAGLRIPG-------------LHPLARLLFPPKDDHTLN
FLYDDNQRVEPEWYIPIIPMVLVNGAEGIGTGWSCKIPNFDVREIVNNIRRLMDGEEPLP
MLPSYKNFKGTIEELASNQYVINGEVAILNSTTIEISELPIRTWTQTYKEQVLEPMLNGT
EKTPPLITDYREYHTD-TTVKFIVKMTEEKLSEVERAGIHKVFKLQTSLTCNSMVLFDHV
GCLKKYDTVLDILRDFFELRLKYYGLRKEWLLGMLGAESSKLNNQARFILEKIDGKIIIE
NKPKKELIKVLIQRGY-----D---SDPVKAWKEAQQKVPEE--EENEESDSEKEAAKGD
PAADSGPTFNYLLD-MPLWYLTKEKKDELCRQRDEKEQELDTLKKKSPSDLWREDLAAFI
EELEVVEAKEKQDEQVGLVGKG---------GKGKGKKA--PA-AETLPSLQGIRVVPRV
TTEMKAEAEKKIRKKLKTENTEGAP-------AEDSVEMDSLKQKLEKK--QKTE---PG
A--KKQTTLPFKPVKKGKKRNPWSDSDSEMSSTSEGHFD---LPSREVKQRRAAANTRFT
MDLDSDEDFSDFDKK-ND----DDFVPSD-A-----SPPKAKSLPQLTKK-EPKPQKSIA
SECLW-----SVS--------VPLVS--------RT----QHPGGA---------RRTLM
SPVRPAGQSSSPTTGAKKRAVPKRAPTAGDKKR

PF08070 // ENSGT00390000016222_1_Domain_9 (1774, 1882)

AVPKR-AK-----KDPALDPEAP-EKP
DPKTKS-RCKRRPSSSSDDSDSSLAKMAPKGARNKRPKAEG-DDFQLD------LQSAVA
PRAKSAR-------ARKPIKYLEESDEDELF-------

---------MEVSPLQPVNENMQVSKTKKNEDAKKRLSVERIYQKKT-QLEHILL-----
---------RP-D-T-YI--GSVESVTQQMWVYDEDTGINYREVTYV

PF02518 // ENSGT00390000016222_1_Domain_0 (108, 255)

PGLYKIFDEILVN
AADNKQRDPKMSCIRITIDPENNLISIWNNGKGIPVVEHKVEKMYVPALIFGQLLTSSNY
DDEEKKVTGGRNGYGAKLCNIFSTKFTVETASREYKKMFKQ--TWMDNMGKAGEMELKPF
SGEDYTCITFHPDLSKFKMQSLDKDIVALMVRRAYDIAGSTKDVKVYLNGNRLP------
--VKGFRSYVDLYLKDKVDETGNPLKIIHEQVNHRWEVCLTMSEKGFQQISFVNSIATS-
----------------------------------KGGRHVDYVADQIVTKLVDVVKKKNK
GGVAVKAHQVKNHMWIFVNALIENPTFDSQTKENMTL-------------------Q-V-
-K--S-F--G-S--T--C-Q--L-S--E--K------------------FIKA-------
-----------------AIGC-GIV-ES-ILN-WVK-FK-AQI-QLN-KKC-SAV-KHN-
RIK-GIP-KLD-DAND-AGGRNSTE--C-TL

PF01751 // ENSGT00390000016222_1_Domain_3 (632, 769)

-ILT-EGD-SAK-TL-AVS-GL-GVV-GR
-DKY-GVF-PL-RGK-ILN-VR-EAS-HKQ-IME-NAE-INN-IIK-IVG-LQY-KKN-Y
ED-EDS-LKT-LRY-GKI-MI-MTD-QDQ-DGS-HIK-GL-LI-NFI-HH-NWP-SL-LR
H-RF-LEE-FI-TPIV-KVS-KNK-QEMAFYSL---PEF-EEWKSST-------PNHKKW
KVKYYKG------------------LGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAIS
LAF-SKKQIDDRKEWLTHFMEDRRQRKLLGLPDDYLYGQATTYLTYNDFINKELILFSNS
DNE

PF00521 // ENSGT00390000016222_1_Domain_6 (964, 1436)

RSIPSMVDGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTII
N--LAQNFVGSNNLNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLARLLFPAKDDHTLK
FLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWSCKIPNFDVREVVNNIRRLMDGEEPLP
MLPSYKNFKGTIEELAPNQYVISGEVAILNSTTIEISELPIRTWTQTYKEQVLEPMLNGT
EKTPPLITDYREYHTD-TTVKFVVKMTEEKLAEAERVGLHKVFKLQTSLTCNSMVLFDHV
GCLKKYDTALDILRDFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIE
NKPKKELIKVLIQRGY-----D---SDPVKAWKEAQQKVPDE--EENEESDNEKESEKSD
SATDSGPTFNYLLD-MPLWYLTKEKKDELCKLRNEKEQELETLKRKSPSDLWKED

ENSGT00390000016222_1_Linker_6_9 (1436, 1773)

LAAFV
EELEVVEAKEKQDEQIGLPGKG---------GKAKGKKT--QM-VEILPSPSGKRVIPRV
TEEMKAEAEKKIKRKIKSENTEGSP-------QEEGMEVESLKLRLEKK--QKRE---PV
TKTKKQTTLPFKPIKKAKKRNPWSDSESDMSS-NESNFD---VPPREKESRRAAAKTKFT
MDLDSDEDFSDFDEDT-QD----DFVPSNA------SPPKIQTSPNRDKA-QIFMYCLYV
LLSFPFEVTELDA--------DDAEDNVPPPPSSPAA---DFPAVTETI-NPVPKKNVTA
KKTA-AKSQ-------------SPTSTTGAKK

PF08070 // ENSGT00390000016222_1_Domain_9 (1773, 1882)

RAAPKR-TK-----KDPDLDSDVS-KKP
NAPKTK-TRRKRKASSSDDSDSNFEKLISKAVTSKKSKEES-DDFHLD------LDSAVG
SRAKSGRT-------KKPIKYLEESDEDDFF-------

------------------------------QTATTHXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXQMWVYDEDIGINYREVTFVPGLYKIFDEILVN
AADNKQRDPKMSCIRVTIDPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTWIDNMGKASEMELKSF
NGEDYTCITFQPDLSKFKMQSLDKDIVALMVRRAYDIAGSTKDVKVFLNGNKLP------
--IKGFRS

PF00204 // ENSGT00390000016222_1_Domain_1 (309, 595)

YVDMYLKDKVDETGNPLKIIHEQVNHRWEVCLTMSEKGFQQISFVNSIATS-
----------------------------------KGGRHVDYVADQIVTKLVDVVKKKNK
GGVAVKAHQSISASNS--------------------------------------------
------------------------------------------------------------
-------PVLAQFFVFFAIGC-GIV-ES-ILN-WVK-FK-AQV-QLN-KKC-SAV-KHN-
RIK-GIP-KLD-DAND-AGGRNSTE--C-TL-ILT-EGD-SAK-TL-AVS-GL-GVV-GR
-DKY-GVF-PL-RGK-ILN-VR-EAS-HKQ-IME-NAE-INN-IIK-IVG-LQY-KKN-Y
ED-EDS-LKT-LRY-GKI-MI-MTD-QDQ-DGS-HIK-GL-LI-NFI-HH-NWP-SL-LR
H-RF-LEE-FI-TPIV-KVS-KNK-QEMAFYSL---PEF-EEWKNST-------PNHKKW
KVKYYKG------------------LGTSTSKEAKEYFADMRRHRIQFKYSGPEDDAAIS
LXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXNDKRVKVAQLAGSVAEMSSYHHGEMSLMMTII
N--LAQNFVGSNNVNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLARLLFPPKDDHTLK
FLYDDNQRIEPEWYIPIIPMVLINGAEGIGTGWSCKIPNFDVREVVNNIRRLMDGEEPLP
MLPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XKTPPLITDYREYHTD-TTVKFVVKMTEEKLAEAERVGLHKVFKLQTSLTCNSMVLFDHV
GCLKKYDTVLDILRDFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIE
NKPKKELIKVLIQRGY-----D---SDPVKAWKEAQQKVPDE--EENEESDNEKDTEKSE
SVTDSGPTFNYLLD-MPLWYLTKEKKDELCKQRNEKEKELETLKRKSPSDLWKEDLAAFI
EELEVVEAKEKQDEQVGLPGKG---------GKAKGKKT--QM-AEVLPSPCGKRVIPRV
TLEMKAEAEKKIKRKIKNENTEGSP-------LEDGVEPESLKQRLEKKQKKETX---XX
XXXXXXXXXXXXXXXXXXXXXXXXX--XXXXX-X-XXXX---XX-X-X-XXXXXXXXXXX
XXXXX--XXXXXXXXXXXXXXXXXXXXXXXX-----XXXXXXXXXXXSTNKELKPQK---
-----SAISDLDT--------DDAKDNVPLSSSSPPA---DLPAETEV-INPVSKKGVTV
KKTAAKSQ--------------SSTSTATTKK

PF08070 // ENSGT00390000016222_1_Domain_9 (1773, 1883)

GAAPKGRAK-----KDPGLNSDTS-QKP
GPAKTK-NPRKRKPSTSDDSDSNFEKMISKAATSKKSKGES-DDFQLD------LDSAVA
PRAKSGR-------AKKPIKYLEESDEDDLF-------

---------MEVSPLQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---XXXXXX-----
---------XX---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXN
AAAIKQRDPKMSCIRVTIDPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTWMDNMGKAGTMELKPF
SGEDYTCITFQPDLSKFKMQSLDKDIVALMFRRAYDIAGSTKDVKVFLNGNKLPXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-
---XXXXXXXXXXXXXXXXXXXXXX--XX-----XXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---------XXXXXXX-
-X--X-X-XX-X--XXXXXX-XX-X--X--X--------XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXAIGC-GIV-ES-ILN-WVK-FK-AQV-QLN-KKC-SAV-KHN-
RIK-GIP-KLD-DANDAXXXXXXXXXXX-XX---X-XXX--XX-XX-XXX-XX-XXX-XX
--XX-XXX-XX-X---XXX-XXXXXXXXXXXIME-NAE-INS-IIK-IVG-LQY-KKN-Y
ED-EDS-LKS-LRY-GKI-MI-MTD-QDQ-DGS-HIK-GL-LI-NFI-HH-NWP-SL-LR
H-RF-LEE-FIT-PIV-KVS-KNK-QEISFYSL---PEF-EEWKSST-------PNHKKW
KVKYYKG------------------LGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAIS
LXXXAKKQIDDRKEWLTHFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNS
DNE

PF00521 // ENSGT00390000016222_1_Domain_6 (964, 1448)

RSIPSMVDGLKPGQRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMSLMMTII
N--LAQNFVGSNNLNLLQPIGQFGTRLHGGKDSASPRYIFTMLXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTQTYKEQVLEM-LN-G
EKTPPLITDYREYHTD-TTVKFVVKMSE-KLAEAERAGLHKVFKLQTSLTCNSMVLFDHV
GCLKKYETALDILRDFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIE
NKPKKELIKVLIQRGY-----D---SDPVKAWKEAQQKVPDE--EENEESDSEKGTDRTD
SVADSGPTFNYLLD-MPLWYLTKEKKDELCKQRNEKEQELEILKKKSPSDLWKEDLAAFI
EELEVVE

ENSGT00390000016222_1_Linker_6_9 (1448, 1773)

AKEKQDEQIGLPGKG---------GKAKGKKAQAQM-TEVLPSPSGRRVIPQV
TSEMKAEAEKKNKKRIKNENVDGIP-------QEDGMEMEGLKKRIEKKRE-------TG
TKAKKQTTLPFKPIKKGKKRNPWSDSESDMSST-ESNFD---VPPRETEPRRAAAKTKFT
MDLDSDEDFSDFEEKD------EDFVPSDAS------PPKTKTSLKKCNKE-VKPQKSTP
PSXXXXXXXXXXX----------------XXXXXXXX---XXXXXX--X-X----X----
---XXXXXXXXXXXXXXXXXXQSSTSTAGTKK

PF08070 // ENSGT00390000016222_1_Domain_9 (1773, 1883)

RAAPKGTKK------KPDLDSDM-SQKP
NPPKTKI-SRKRKPSTSDDSDSNFEKIVSKAVTSKKSKGDN-DDFHLD--------TDLA
PRAKSVR-------AKKPIKYLEESDEDDLF-------

---------MEVSPLQPVNENMQINK-KKNEDAKKRLSIERIYQKKT-QLEHILL-----
---------RP-D-T-YI--GSVELVTQQMWVYDEDIGINYREV

PF02518 // ENSGT00390000016222_1_Domain_0 (105, 255)

TFVPGLYKIFDEILVN
AADNKQRDPKMSCIRVTIDPENNLISIWNNGKGIPVVEHKVEKMYVPALIFGQLLTSSNY
DDDEKKVTGGRNGYGAKLCNIFSTKFTVETASREYKKMFKQ--TWMDNMGRAGEMELKPF
NGEDYTCITFQPDL

ENSGT00390000016222_1_Linker_0_1 (255, 309)

SKFKMQSLDKDIVALMVRRAYDIAGSTKDVKVFLNGNKLP------
--VKGFRS

PF00204 // ENSGT00390000016222_1_Domain_1 (309, 595)

YVDMYLKDKVDETGNPLKVIHEQVNHRWEVCLTMSEKGFQQISFVNSIATS-
----------------------------------KGGRHVDYVTDQIVTKLVDVVKKKNK
GGVAVKAHQVKNHMWIFVNALIENPTFDSQTKENMTL-------------------Q-A-
-K--S-F--G-S--T--C-Q--L-S--E--K------------------FIKA-------
-----------------AIGC-GIV-ES-ILN-WVK-FK-AQV-QLN-KKC-SAV-KHN-
RIK-GIP-KLD-DAND-AGSRNSAD--C-TL-ILT-EGD-SAK-TL-AVS-GL-GVV-GR
-DKY-GVF-PL-RGK-ILN-VR-EAS-HKQ-IME-NAE-INN-IIK-IVG-LQY-KKN-Y
ED-EDS-LKT-LRY-GKI-MI-MTD-QDQ-DGS-HIK-GL-LI-NFI-HH-NWP-SL-LR
H-RF-LEE-FI-TPIV-KVS-KNK-QEMSFYSL---PEF-EEWKNST-------PNHKKW
KVKYYKG------------------LGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAIS
LAF-SKKQTDDRKEWLTHFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNS
DNERSIPSMVDGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTII
N--LAQNFVGSNNLNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLARLLFPPKDDNTLK
FLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWSCKIPNFDIREVVNNIRRLMDGEEPLP
MLPSYKNFKGTIEELASNQYVISGEVAILNSTTIEISELPIRTWTQTYKEQVLEPMLNGT
EKTPPLITDYREYHTD-TTVKFVVKMTEEKLAEAERVGLHKVFKLQTSLTCNSMVLFDHV
GCLKKYDTVLDILRDFYELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIE
NKPKKELIKVLIQRGY-----D---SDPVKAWKEAQQKVTEE--EENEESDNEKETEKSD
S--ASGPTFNYLLD-MPLWYLTKEKKDELCKQRNEKEQELETLKRKSPSDLWKEDLAAFI
EELEAVEAKEKQDEQVGLPGKG---------GKGKGKKT--QM-AEVLPSPSGKRVVPRV
TIEMKAEAEKKIRRKIKNENTEGSP-------QEDSVEPESLKQRLEKK--QKRE---PG
NKAKKQTTLPFKPIQKGKKRNPWSDSESDMSG-NESDFD---VPPREVEPRRAATKAKFT
VDLDSDEDFSDIDKKS-ED---EDFVPSDA------SPVKTKTSPKHTNK-ELKPQKSTT
SVKRGSRLLSWGG--------QIHL--------GSNA---DYISQ-----ALPLKINVTV
KKTA-AKSQ-------------SSTSTTGAKK

PF08070 // ENSGT00390000016222_1_Domain_9 (1773, 1883)

RAAPKG-TK-----KDPSLTSDVP-QKP
DPPKTK-IRRKRKASSSDDSDSNFEKMISKAVTSKKSKGES-DDFHMD------LDSAVA
PRVKSGR-------TKKPIKYLEESDEDLF--------

-----------TSPLHPVNENMQINKTKKNEDAKKRLSIERIYQKKT-QLEHILL-----
---------RP-D-T-YI--GSVELVT-QMWVYDEDIGINYREV

PF02518 // ENSGT00390000016222_1_Domain_0 (105, 255)

TFVPGLYKIFDEILVN
AADNKQRDPKMSCIRVTIDPENNLISIWNNGKGIPVVEHKVEKMYVPALIFGQLLTSSNY
DDDEKKVTGGRNGYGAKLCNIFSTKFTVETASREYKKMFKQ--TWMDNMGRAGEMELKPF
NGEDYTCITFQPDL

ENSGT00390000016222_1_Linker_0_1 (255, 309)

SKFKMQSLDKDIVALMV-RAYDIAGXXXXXXXXXXXXXXX------
--VKGFRS

PF00204 // ENSGT00390000016222_1_Domain_1 (309, 595)

YVDMYLKDKVDETGNPLKIIHEQVNHRWEVCLTMSEKGFQQISFVNSIATS-
----------------------------------KGGRHVDYVADQIVTKLVDVVKKKNK
GGVAVKAHQTYPTCSSAL------------------------------------------
-----------------A-Q--F-F--E--------------------------------
-------------LFLWAIGC-GIV-ES-ILN-WVK-FK-AQI-QLN-KKC-SAV-KHN-
RIK-GIP-KLD-DAND-AGGRNSTE--C-TL-ILT-EGD-SAK-TL-AVS-GL-GVV-GR
-DRY-GVF-PL-RGK-ILN-VR-EAS-HKQ-IME-NAE-INN-IIK-IVG-LQY-KKN-Y
ED-EDS-LKT-LRY-GKI-MI-MTD-QDQ-DGS-HIK-GL-LI-NFI-HH-NWP-SL-LR
H-RF-LEE-FI-TPIV-KVS-KNK-QEMAFYSL---PEF-EEWKSST-------PNHKKW
KVKYYKG------------------LGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAIS
LAF-SKKQIDDRKEWLTHFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNS
DNERSIPSMVDGLKPGQRKVLFT-FKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTII
N--LAQNFVGSNNLNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLARLLFPPQDDHTLK
FLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWSCKIPNFDIREVVNNIRLLMDGEEPLP
MLPSYKNFKGTIEELAPNQYVISGEVAILNSTTIEISELPIRTWTQTYKEQVLEPMLNGT
EKTPPLITDYREYHTD-TTVKFVVKMTEEKLAEAERVGLHKVFKLQTSLTCNSMVLFDHV
GCLKKYDTALDILRDFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIE
NKPKKELIKVLIQRGY-----D---SDPVKAWKEAQQKVPDE--EENEESDNEKETEKSD
SV--TGPTFNYLLD-MPLWYLTKEKKDELCKLRKEKEQELETLKKKSPSDLWKEDLAAFI
EELETVEAKEKQDEQVGLPGKG---------GKGKGKKT--QM-AEVLPSPSGKRVIPRV
TIEMKAEAEKKIKRKIKNENSEGTP-------QENGMEPESLKQRLEKK--LKKE---PG
TKTKKQTTLPFKPVKKGKKRNPWSDSESDASS-NESDFD---VPPREIEPRRAATKTKFT
VDLDSDEDFSDFDQET-QD---EDFVPSD-A-----SPVKTRTSPKRTNK-ELKPQKSTT
S--------DFDA--------DDAKDPSPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
X--X-XXXX-------------XXX-XXXXXXXXXXXX-XX-----X-XXX-X----XXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX

PF08070 // ENSGT00390000016222_1_Domain_9 (1836, 1883)

KSRGES-DDFHLD------LDSAVA
PRVKSGR-------AKKPIKYLEESDEDDLF-------

---------MELSPLQPVNENMQMNKTKKNEDAKKRLSVERIYQKKT-QLEHILL-----
---------RP---DTYI--GSVELVTQHMWVYDEDIGINYREVTFV

PF02518 // ENSGT00390000016222_1_Domain_0 (108, 255)

PGLYKIFDEILVN
AADNKQRDPKMSCIRVTIDPENNLISIWNNGKGIPVVEHKVEKVYVPALIFGQLLTSSNY
DDDEKKVTGGRNGYGAKLCNIFSTKFTVETASKEYKKMFKQ--TWRDNMGRAGEMELRPF
SGEDYTCITFQPDLSKFKMQSLDKDIVALMVRRAYDIAGSTKDVKVFLNGNKLP------
--VKGFRSYVDMYLKDKLDETGNPLKVIHEQVNHRWEVCLTMSEKGFQQISFVNSIATS-
----------------------------------KGGRHVDYVADQIVTKLVDVVKKKNK
GGVAVKAHQVKNHMWIFVNALIENPTFDSQTKENMTLQAKS-------------------
------F--G-----STCQL--------------------------SEKFIKA-------
-----------------AIGC-GIV-ES-ILN-WVK-FK-AQV-QLN-KKC-SAV-KHN-
RIK-GIP-KLD-DAND-AGSRNSTE--C-TL

PF01751 // ENSGT00390000016222_1_Domain_3 (632, 769)

-ILT-EGD-SAK-TL-AVS-GL-GVV-GR
-DRY-GVF-PL-RGK-ILN-VR-EAS-HKQ-IME-NAE-INN-IIK-IVG-LQY-KKN-Y
ED-EDS-LKT-LRY-GKI-MI-MTD-QDQ-DGS-HIK-GL-LI-NFI-

ENSGT00390000016222_1_Linker_3_5 (769, 790)

HH-NWP-SL-LR
H-CF-LEE-

PF16898 // ENSGT00390000016222_1_Domain_5 (790, 962)

FI-TPIV-KVS-KNK-QEMAFYSL---PEF-EEWKSST-------PNHKKW
KVKYYKG------------------LGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAIS
LAF-SKKQIDDRKEWLTHFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNS
DNERSIPSMVDGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTII
N--LAQNFVGSNNLNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLARLLFPPKDDHTLK
FLYDDNQRVEPEWYIPVIPMVLVNGAEGIGTGWSCKIPNFDVREVVDNIRRLMDGEEPLP
MLPSYKNFKGTIEELAPNQYVINGEVAILNSTTIEISELPIRTWTQMYKEQVLEPMLNGT
EKTPPLITDYREYHTD-TTVKFVVKMTEEKLAEAERAGLHKVFKLQTSLTCNSMVLFDHV
GCLKKYDTALDILRDFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIE
NKPKKELIKVLIQRGY-----D---SDPVKAWKEAQLKVPDE--EENEESDSEKETARGD
SAAGAGPTFNYLLD-MPLWYLTKEKKDELCKQRSEKEQELDALKKKSPSDLWREDLAAFV
EELEAVEAKEKQDEQVGLAGKG---------GKARGKKA--QM-ADVLPSQQGTRVIPRV
TTEMKAEAEKKIKKKIKSENTEGTP-------AEDSVEPESLKQRLEKK--QRRE---PG
ARAKKQTTLPFKPVRKGKKRNPWSDSESDMSS-NESNFD---VPPREIEPRRAAAKTKFT
MDLDSDEDVSDFDEEPEE----DGFVPSG-A-----SPPKPRAPPKLIKKEEPKPQKSIM
SGVSG-----LQA--------EAAEDREP-----PA----DLPAGTEAA-KLPPQRSAAL
K-TAGRGH--------------PSASIAGTRK

PF08070 // ENSGT00390000016222_1_Domain_9 (1773, 1882)

RAAPKG-TK-----RDPARNSEAS-QKP
DPAKTK-YRRKRKPSTSDDSDSTFEKVISRGATSKKSKAES-DDFQMA------LDSAVA
PRAKSVR-------AKKPIKYLEESDDNDLF-------

---------MEVSPLQPVNENMQVNKIKKNEDAKKRLSVERIYQKKT-QLEHILL-----
---------RP-D-T-YI--GSVELVTQQMWVYDEDVGINYREVTFV

PF02518 // ENSGT00390000016222_1_Domain_0 (108, 255)

PGLYKIFDEILVN
AADNKQRDPKMSCIRVTIDPENNLISIWNNGKGIPVVEHKVEKMYVPALIFGQLLTSSNY
DDDEKKVTGGRNGYGAKLCNIFSTKFTVETASREYKKMFKQ--TWMDNMGRAGEMELKPF
NGEDYTCITFQPDLSKFKMQSLDKDIVALMVRRAYDIAGSTKDVKVFLNGNKLP------
--VKGFRSYVDMYLKDKLDETGNSLKVIHEQVNHRWEVCLTMSEKGFQQISFVNSIATS-
----------------------------------KGGRHVDYVADQIVTKLVDVVKKKNK
GGVAVKAHQVKNHMWIFVNALIENPTFDSQTKENMTL-------------------Q-P-
-K--S-F--G-S--T--C-Q--L-S--E--K------------------FIKA-------
-----------------AIGC-GIV-ES-ILN-WVK-FK-AQV-QLN-KKC-SAV-KHN-
RIK-GIP-KLD-DAND-AGGRNSTE--C-TL

PF01751 // ENSGT00390000016222_1_Domain_3 (632, 769)

-ILT-EGD-SAK-TL-AVS-GL-GVV-GR
-DKY-GVF-PL-RGK-ILN-VR-EAS-HKQ-IME-NAE-INN-IIK-IVG-LQY-KKN-Y
ED-EDS-LKT-LRY-GKI-MI-MTD-QDQ-DGS-HIK-GL-LI-NFI-HH-NWP-SL-LR
H-RF-LEE-FI-TPIV-KVS-KNK-QEMAFYSL---PEF-EEWKSST-------PNHKKW
KVKYYKG------------------LGTSTSKEAKEYFADMKRHRIQFRYSGPEDDAAIS
LAF-SKKQIDDRKEWLTNFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNS
DNE

PF00521 // ENSGT00390000016222_1_Domain_6 (964, 1436)

RSIPSMVDGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTII
N--LAQNFVGSNNLNLLQPIGQFGTRLHGGKDSASPRYIFTMLSSLARLLFPPKDDHTLK
FLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWSCKIPNFDVREIVNNIRRLMDGEEPLP
MLPSYKNFKGTIEELAPNQYVISGEVAILNSTTIEISELPVRTWTQTYKEQVLEPMLNGT
EKTPPLITDYREYHTD-TTVKFVVKMTEEKLAEAERVGLHKVFKLQTSLTCNSMVLFDHV
GCLKKYDTVLDILRDFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIE
NKPKKELIKVLIQRGY-----D---SDPVKAWKEAQQKVPDE--EENEESDNEKETEKSD
SVTDSGPTFNYLLD-MPLWYLTKEKKDELCRLRNEKEQELDTLKRKSPSDLWKED

ENSGT00390000016222_1_Linker_6_9 (1436, 1773)

LATFI
EELEAVEAKEKQDEQVGLPGKG---------GKAKGKKT--QT-AEVLPSPCGQRVIPRI
TIEMKAEAEKKNKKKIKNENTEGSP-------QEDGMELEGLKQRLEKK--QKRE---PG
TKTKKQTTLPFKPIKKGKKRNPWSDSESDRSS-DESNFD---VPPRETEPRRAATKTKFT
MDLDSDEDFSDFDEK-TDD---EDFVPSD-A-----SPPKTKTSPKLSNK-ELKPQK---
SVVSDLEAD--D---------AK--DSVPLSSSPPAT---HFPDETEIT-NPVPKKNVTM
KKTA-AKSQ-------------SSTSTTGAKK

PF08070 // ENSGT00390000016222_1_Domain_9 (1773, 1882)

RAAPKG-TK-----RDPALNSGVS-QKP
DPAKTK-NRRKRKPSTSDDSDSNFEKIVSKAVTSKKSKGES-DDFHMD------FDSAVA
PRAKSVR-------AKKPIKYLEESDEDDLF-------

---------MEVSPLQPVNENMKIDKIKKNEDAKKRLSIERIYQKKT-QLEHILL-----
---------RP-D-T-YI--GSVELVTQQMWVYDEDVGINYREVTFV

PF02518 // ENSGT00390000016222_1_Domain_0 (108, 255)

PGLYKIFDEILVN
AADNKQRDPKMSCIRVTIDPENNLISIWNNGKGIPVVEHKVEKMYVPALIFGQLLTSSNY
DDDEKKVTGGRNGYGAKLCNIFSTKFTVETASREYKKMFKQ--TWRDNMGRAGEMELKPF
NGEDYTCITFQPDL

ENSGT00390000016222_1_Linker_0_1 (255, 305)

SKFKMQSLDKDIVALMVRRAYDIAGSTKDVKVFLNGNKLP------
--VK

PF00204 // ENSGT00390000016222_1_Domain_1 (305, 590)

GFRSYVDMYLKDKVDETGNPLKVIHEQVNHRWEVCLTMSEKGFQQISFVNSIATS-
----------------------------------KGGRHVDYVADQIVAKLVDVVKKKNK
GGVAVKAHQVKNHMWIFVNALIENPTFDSQTKENMTL-------------------Q-A-
-K--S-F--G-S--T--C-Q--L-S--E--K------------------FIKA-------
-----------------AIGC-GIV-ES-ILN-WVK-FK-AQV-QLN-K

ENSGT00390000016222_1_Linker_1_3 (590, 632)

KC-SAV-KHN-
RIK-GIP-KLD-DAND-AGGRNSTE--C-TL

PF01751 // ENSGT00390000016222_1_Domain_3 (632, 769)

-ILT-EGD-SAK-TL-AVS-GL-GVV-GR
-DKY-GVF-PL-RGK-ILN-VR-EAS-HKQ-IME-NAE-INN-IIK-IVG-LQY-KKN-Y
ED-EDS-LKT-LRY-GKI-MI-MTD-QDQ-DGS-HIK-GL-LI-NFI-HH-NWP-SL-LR
H-RF-LEE-FI-TPIV-KVS-KNK-QEMAFYSL---PEF-EEWKSST-------PNHKKW
KVKYYKG------------------LGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAIS
LAF-SKKQIDDRKEWLTHFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNS
DNERSIPSMVDGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTII
N--LAQNFVGSNNLNLLQPIGQFGTRLHGGKDSASPRYIFTMLSSLARLLFPPKDDHTLK
FLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWSCKIPNFDVREVVNNIRRLMDGEEPLP
MLPSYKNFKGTIEELAPNQYVISGEVAILDSTTIEISELPIRTWTQTYKEQVLEPMLNGT
EKTPPLITDYREYHTD-TTVKFVVKMTEEKLAETEKAGLHKVFRLQTSLTCNSMVLFDHV
GCLKKYDTVLDILRDFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIEGKIIIE
NKPKKEIIKVLVQRGY-----D---SDPVKAWKEAQQKVPDE--EENEESDNEKETEKSD
SVTDSGPTFNYLLD-MPLWYLTKEKKDELCKLRNEKEQELDTLRKKTPSDLWKEDLAAFI
EELEAVEAKEKQDEQVGLPGKG---------GKAKGKKT--QM-AEVLPSPRGKRVIPQV
TIEMKAEAEKKNRKKIKSENTERSP-------QEDGMELESLKQRLEKK--QKRE---PG
TKRKKQTTLPFKPVKKGSKRNPWSDSESDMSS-NDSNFD---VPPRETEPRRTTTKTKFT
MDLDSDDDFSDFDEK-TQD---EDFVPSD-A-----SPPKTKIPPKHTTK-ELKPQN---
SGKSEKDLD--S----------NDKDSVPLSSSPLAS---DFSQGPVSK-------KINF
DSLMLQTSQ-------------SSTSTTGA-K

PF08070 // ENSGT00390000016222_1_Domain_9 (1773, 1882)

KAAPKG-TR-----KNPALNSGVS-QKP
DPAKTK-NRRKRKPSTSDDSDSNFEKIISKAATSKKSKGES-DDFHLD------FDSAVA
PRAKSSR-------AKKPIKYLEESDEDDLF-------

---------MEVSPLQPVNENMQVNKIKKNEDAKKRLSVERIYQKKT-QLEHILL-----
---------RP-D-T-YI--GSVELVTQQMWVYDEDVGINYREVTFV

PF02518 // ENSGT00390000016222_1_Domain_0 (108, 255)

PGLYKIFDEILVN
AADNKQRDPKMSCIRVTIDPENNLISIWNNGKGIPVVEHKVEKMYVPALIFGQLLTSSNY
DDDEKKVTGGRNGYGAKLCNIFSTKFTVETASREYKKMFKQ--TWMDNMGRAGEMELKPF
NGEDYTCITFQPDLSKFKMQSLDKDIVALMVRRAYDIAGSTKDVKVFLNGNKLP------
--VKGFRSYVDMYLKDKLDETGNSLKVIHEQVNHRWEVCLTMSEKGFQQISFVNSIATS-
----------------------------------KGGRHVDYVADQIVTKLVDVVKKKNK
GGVAVKAHQVKNHMWIFVNALIENPTFDSQTKENMTL-------------------Q-P-
-K--S-F--G-S--T--C-Q--L-S--E--K------------------FIKA-------
-----------------AIGC-GIV-ES-ILN-WVK-FK-AQV-QLN-KKC-SAV-KHN-
RIK-GIP-KLD-DAND-AGGRNSTE--C-TL

PF01751 // ENSGT00390000016222_1_Domain_3 (632, 769)

-ILT-EGD-SAK-TL-AVS-GL-GVV-GR
-DKY-GVF-PL-RGK-ILN-VR-EAS-HKQ-IME-NAE-INN-IIK-IVG-LQY-KKN-Y
ED-EDS-LKT-LRY-GKI-MI-MTD-QDQ-DGS-HIK-GL-LI-NFI-HH-NWP-SL-LR
H-RF-LEE-FI-TPIV-KVS-KNK-QEMAFYSL---PEF-EEWKSST-------PNHKKW
KVKYYKG------------------LGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAIS
LAF-SKKQIDDRKEWLTNFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNS
DNE

PF00521 // ENSGT00390000016222_1_Domain_6 (964, 1436)

RSIPSMVDGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTII
N--LAQNFVGSNNLNLLQPIGQFGTRLHGGKDSASPRYIFTMLSSLARLLFPPKDDHTLK
FLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWSCKIPNFDVREIVNNIRRLMDGEEPLP
MLPSYKNFKGTIEELAPNQYVISGEVAILNSTTIEISELPVRTWTQTYKEQVLEPMLNGT
EKTPPLITDYREYHTD-TTVKFVVKMTEEKLAEAERVGLHKVFKLQTSLTCNSMVLFDHV
GCLKKYDTVLDILRDFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIE
NKPKKELIKVLIQRGY-----D---SDPVKAWKEAQQKVPDE--EENEESDNEKETEKSD
SVTDSGPTFNYLLD-MPLWYLTKEKKDELCRLRNEKEQELDTLKRKSPSDLWKED

ENSGT00390000016222_1_Linker_6_9 (1436, 1773)

LATFI
EELEAVEAKEKQDEQVGLPGKG---------GKAKGKKT--QM-AEVLPSPRGQRVIPRI
TIEMKAEAEKKNKKKIKNENTEGSP-------QEDGVELEGLKQRLEKK--QKRE---PG
TKTKKQTTLAFKPIKKGKKRNPWSDSESDRSS-DESNFD---VPPRETEPRRAATKTKFT
MDLDSDEDFSDFDEK-TDD---EDFVPSD-A-----SPPKTKTSPKLSNK-ELKPQK---
SVVSDLEAD--D---------VK--GSVPLSSSPPAT---HFPDETEIT-NPVPKKNVTV
KKTA-AKSQ-------------SSTSTTGAKK

PF08070 // ENSGT00390000016222_1_Domain_9 (1773, 1882)

RAAPKG-TK-----RDPALNSGVS-QKP
DPAKTK-NRRKRKPSTSDDSDSNFEKIVSKAVTSKKSKGES-DDFHMD------FDSAVA
PRAKSVR-------AKKPIKYLEESDEDDLF-------

---------MELSPLQPVNENMLMNK-KKNEDGKKRLSIERIYQKKT-QLEHILL-----
---------RP-D-T-YI--GSVELVTQQMWVYDEDVGINYREVTFV

PF02518 // ENSGT00390000016222_1_Domain_0 (108, 255)

PGLYKIFDEILVN
AADNKQRDPKMSCIRVTIDPENNVISIWNNGKGIPVVEHKVEKIYVPALIFGQLLTSSNY
DDDEKKVTGGRNGYGAKLCNIFSTKFTVETASREYKKMFKQ--TWMDNMGRAGDMELKPF
SGEDYTCITFQPDLSKFKMQSLDKDIVALMVRRAYDIAGSTKDVKVFLNGNSLP------
--VKGFRSYVDLYLKDKVDETGNSLKVIHEQVNPRWEVCLTMSERGFQQISFVNSIATS-
----------------------------------KGGRHVDYVADQIVSKLVDVVKKKNK
GGVAVKAHQVKNHMWIFVNALIENPTFDSQTKENMTL-------------------Q-A-
-K--S-F--G-S--T--C-Q--L-S--E--K------------------FIKA-------
-----------------AIGC-GIV-ES-ILN-WVK-FK-AQI-QLN-KKC-SAV-KHT-
KIK-GIP-KLD-DAND-AGSRNSTE--C-TL

PF01751 // ENSGT00390000016222_1_Domain_3 (632, 769)

-ILT-EGD-SAK-TL-AVS-GL-GVV-GR
-DKY-GVF-PL-RGK-ILN-VR-EAS-HKQ-IME-NAE-INN-IIK-IVG-LQY-KKN-Y
ED-EDS-LKT-LRY-GKI-MI-MTD-QDQ-DGS-HIK-GL-LI-NFI-HH-NWP-SL-LR
H-RF-LEE-FI-TPIV-KVS-KNK-QEIAFYSL---PEF-EEWKSST-------PNHKKW
KVKYYKG------------------LGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAIS
LAF-SKKQVDDRKEWLTNFMEDRRQRKLLGLPEDYLYGQSTSYLTYNDFINKELILFSNS
DNE

PF00521 // ENSGT00390000016222_1_Domain_6 (964, 1436)

RSIPSMVDGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTII
N--LAQNFVGSNNLNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLARLLFPPKDDHTLR
FLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWSCKIPNFDVREVVNNIRRLLDGEEPLP
MLPSYKNFKGTIEELASNQYVINGEVAILDSTTIEISELPIRTWTQTYKEQVLEPMLNGT
EKTPSLITDYREYHTD-TTVKFVIKMTEEKLAEAERVGLHKVFKLQSSLTCNSMVLFDHV
GCLKKYDTVLDILRDFFELRLKYYGLRKEWLLGMLGAESSKLNNQARFILEKIDGKIVIE
NKPKKELIKVLIQRGY-----D---SDPVKAWKEAQQKVPDE--EENEESDT--ETSTSD
SAAEAGPTFNYLLD-MPLWYLTKEKKDELCKQRNEKEQELNTLKQKSPSDLWKED

ENSGT00390000016222_1_Linker_6_9 (1436, 1773)

LAVFI
EELEVVEAKEKQDEQVGLPGKA---------GKAKGKKA--QMCADVLPSPRGKRVIPQV
TVEMKAEAEKKIRKKIKSENVEGTP-------AEDGAEPGSLRQRIEKK--QKKE---PG
--AKKQTTLPFKPVKKGRKKNPWSDSESDVSS-NESNVD---VPPRQKEQRSAAAKAKFT
VDLDSDEDFSGLDEKD-ED---EDFLPLD-A-----TPPKAKIPPKNTKK-ALKTQGSSM
SVV------DLE---------SDVKDSVPASPGVPA---ADFPAETEQS-KPSK-KTVGV
KKTATKSQS-------------SVS-TAGTKK

PF08070 // ENSGT00390000016222_1_Domain_9 (1773, 1882)

RAAPKG-TK-----SDSALSARVS-EKP
APAKAKN-SRKRKPSSSDSSDSDFERAISKGATSKKAKGEE-QDFPVD------LEDTIA
PRAKSDR-------ARKPIKYLEESDDDD---DLF---

----------QASPRHPVDDNMQVNKTKKNEDAKKRLSIERIYQKKT-QLEHILL-----
---------RP-D-T-YI--GSVESVTQQMWVYDEDIGINCREV

PF02518 // ENSGT00390000016222_1_Domain_0 (105, 255)

TFVPGLYKIFDEILVN
AADNKQRDPKMSCIRVTIDPENNLISIWNNGKGIPVVEHKVEKMYVPALIFGQLLTSSNY
DDEEKKVTGGRNGYGAKLCNIFSTKFTVETASREYKKMFKQ--TWRDNMGRAGEMELKPF
SGEDYTCITFHPDLSKFKMQNLDKDIVALMVRRAYDIAGSTKDVKVFLNGNKLP------
--IKGFRSYVDMYLKDKVDETGNALKIIHEQVNPRWEVCLTMSEKGFQQISFVNSIATS-
----------------------------------KGGRHVDYVADQIVTKLVDVVKKKNK
GGVAVKAHQNRSP-WSS-------------------------------------------
-----------V--L--A-Q--F-F--E--F------------------FLFL-------
-----------------AIGC-GIV-ES-ILN-WVK-FK-AQV-QLN-KKC-SAV-KHN-
RIK-GIP-KLD-DAND-AGGRNSTE--C-TL-ILT-EGD-SAK-TL-AVS-GL-GVV-GR
-DKY-GVF-PL-RGK-MLN-VR-EAS-HKQ-IME-NAE-INN-IIK-IVG-LQY-KKN-Y
ED-EDS-LKT-LRY-GKI-MI-MTD-QDQ-DGS-HIK-GL-LI-NFI-HH-NWP-SL-LH
H-RF-LEE-FI-TPIV-KVS--NK-QEVAFYSL---PEF-EEWKNST-------PNHKKW
KVKYYKG------------------LGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAIS
LAF-SKKQIDDRKEWLTHFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNS
DNE

PF00521 // ENSGT00390000016222_1_Domain_6 (964, 1448)

RSIPSMVDGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTII
N--LAQNFVGSNNLNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLARLLFPPKDDHTLR
FLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWSCKIPNFDVREVVNNIRRLMDGEEPLP
MLPSYKNFKGTVEELAPNQYVISGEMSILNSTTIEISELPIRTWTQTYKEQVLEPMLNGT
EKTPPLITDYREYHTD-TTVKFVVKMTEEKLAEAERVGLHKVFKLQTSLTCNSMVLFDHV
GCLKKYDTVLDILRDFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIE
NKPKKELIKVLIQRGY-----D---SDPVKAWKEAQQKVADE--EENEESDNEKETEKSD
SVTDSGPTFNYLLD-MPLWYLTKEKKDELCRLRNEKEQELETLKRKSPSDLWKEDLAAFV
EELEAVE

ENSGT00390000016222_1_Linker_6_9 (1448, 1773)

AKEKQDEQIGLPGKG---------GKAKGKKT--QR-AEVLPSPCGKRVIPQV
TIEMKAEAEKKIKKKIKXXXXXXXX-------XXXXXXXXXXXXXXXXX--XXXX---XX
TKTKKQTTLPFKPVKKAKKRNPWSDSESDIDS-NESNFD---VPPREKEPRRAATKTKFT
MDLDSDEDFSDFDENT-QD---EDRVPSDA------SPPRTTTSPKHTNK-ELKPQKSA-
-------TSDLNA--------DDAKDNVPPPPSSPAA---DFPAVTK-TTNPVPKKNVTV
KKTA-AKSQ-------------SSTSTTGAKK

PF08070 // ENSGT00390000016222_1_Domain_9 (1773, 1883)

RAAPKG-TK-----KDPDLDSDVS-KKP
NPPKTK-SHRKRKPSTSDDSDSNFEKMISKAVTSKKPKEDS-DDFHLD------LDSAVA
SRAKSGR-------TKKPIKYLEESDEDDLF-------

---------MELSPLQPVNENMLMNK-KKNEDGKKRLSIERIYQKKT-QLEHILL-----
---------RP-D-T-YI--GSVELVTQQMWVYDEDVGINYREVTFV

PF02518 // ENSGT00390000016222_1_Domain_0 (108, 255)

PGLYKIFDEILVN
AADNKQRDPKMSCIKVTIDPENNVISIWNNGKGIPVVEHKVEKIYVPALIFGQLLTSSNY
DDDEKKVTGGRNGYGAKLCNIFSTKFTVETASREYKKMFKQ--TWMDNMGRAGDMELKPF
SGEDYTCITFQPDLSKFKMQSLDKDIVALM------------------------------
--VKGFRSYVDLYLKDKVDETGNALKVIHEQVNPRWEVCLTMSERGFQQISFVNSIATS-
----------------------------------KGGRHVDYVADQIVSKLVDVVKKKNK
GGVAVKAHQVKNHMWIFVNALIENPTFDSQTKENMTL-------------------Q-A-
-K--S-F--G-S--T--C-Q--L-S--E--K------------------FIKA-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------VS-KNK-QEIAFYSL---PEF-EEWKSST-------PNHKKW
KVKYYKG------------------LGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAIS
LAF-SKKQVDDRKEWLTNFMEDRRQRKLLGLPEDYLYGQSTSYLTYNDFINKELILFSNS
DNE

PF00521 // ENSGT00390000016222_1_Domain_6 (964, 1436)

RSIPSMVDGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTII
N--LAQNFVGSNNLNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLARLLFPPKDDHTLR
FLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWSCKIPNFDVREVVNNIRRLLDGEEPLP
MLPSYKNFKGTIEELASNQYVINGEVAILDSTTIEISELPIRTWTQTYKEQVLEPMLNGT
EKTPSLITDYREYHTD-TTVKFVIKMTEEKLAEAERVGLHKVFKLQSSLTCNSMVLFDHV
GCLKKYDTVLDILRDFFELRLKYYGLRKEWLLGMLGAESSKLNNQARFILEKIDGKIVIE
NKPKKELIKVLIQRGY-----D---SDPVKAWKEAQQKVPDE--EENEESDT--ETSTSD
SAAEAGPTFNYLLD-MPLWYLTKEKKDELCKQRNEKEQELNTLKQKSPSDLWKED

ENSGT00390000016222_1_Linker_6_9 (1436, 1743)

LAVFI
EELEVVEAKEKQDEQVGLPGKA---------GKGKGKKA--QMCADVLPSPRGKRVIPQV
TVEMKAEAEKKIRRKIKSENVEGTP-------AEDGVETGSLRQRIEKK--QKRE---PG
--AKKQTTLPFKPIKKGKKKNPWSDSESDMSS-NESNFD---VPPREKEQRSAAAKAKFT
VDLDSHEDFSGADEKD-ED---EDFFPLD-A-----TPPKTKIPPKNTKK-ALKAQKSSM
-FA------DLE---------RDVKDSVPASSGVPAASATDFPAETEQS-KPSSKKTVGV
KR

PF08070 // ENSGT00390000016222_1_Domain_9 (1743, 1863)

TATK----------------------STKKRAAQKG-TK-----SDLTFSDHVS-EKS
APAKTKN-RSKRKPSSSDSSDSDFEKAISKGAKSKKPKGEE-QVFHVD------LEDTVA
PQAKSG--------------------------------

---------MEVSPLQPVNENMQVNKIKKNEDAKKRLSIERIYQKKT-QLEHILL-----
---------RP-D-T-YI--GSVELVTQQMWVYDEDVGINYREVTFV

PF02518 // ENSGT00390000016222_1_Domain_0 (108, 255)

PGLYKIFDEILVN
AADNKQRDPKMSCIRVTIDPENNLISIWNNGKGIPVVEHKVEKMYVPALIFGQLLTSSNY
DDDEKKVTGGRNGYGAKLCNIFSTKFTVETASREYKKMFKQ--TWMDNMGRAGEMELKPF
SGEDYTCITFQPDLSKFKMQSLDKDIVALMVRRAYDIAGSTKDVKVFLNGNKLP------
--VKGFRSYVDMYLKDKLDETGNPLKVIHEQVNHRWEVCLTMSEKGFQQISFVNSIATS-
----------------------------------KGGRHVDYVADQIVTKLVDVVKKKNK
GGVAVKAHQVCAF----GSFLFLKSRKKRKTKENMTL-------------------Q-P-
-K--S-F--G-S--T--C-Q--L-S--E--N------------------LS---------
--------------------------KL-ILN-WVK-FK-AQV-QLN-KKC-SAV-KHN-
RIK-GIP-KLD-DAND-AGGRNSAD--C-TL

PF01751 // ENSGT00390000016222_1_Domain_3 (632, 769)

-ILT-EGD-SAK-TL-AVS-GL-GVV-GR
-DKY-GVF-PL-RGK-ILN-VR-EAS-HKQ-IME-NAE-INN-IIK-IVG-LQY-KKN-Y
ED-EDS-LKT-LRY-GKI-MI-MTD-QDQ-DGS-HIK-GL-LI-NFI-HH-NWP-SL-LR
H-RF-LEE-FI-TPIV-KVS-KNK-QEMAFYSL---PEF-EEWKSST-------PNHKKW
KVKYYKG------------------LGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAIS
LAF-SKKQIDDRKEWLTNFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNS
DNE

PF00521 // ENSGT00390000016222_1_Domain_6 (964, 1436)

RSIPSMVDGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTII
N--LAQNFVGSNNLNLLQPIGQFGTRLHGGKDSASPRYIFTMLSSLARLLFPPKDDHTLR
FLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWSCKIPNFDVREVVNNIRRLMDGEEPLP
MLPSYKNFKGTIEELAPNQYVISGEVAILNSTTIEISELPIRTWTQTYKEQVLEPMLNGT
EKTPPLITDYREYHTD-TTVKFVVKMTEGKLAEAERVGLHKVFKLQTSLTCNSMVLFDHV
GCLKKYDTVLDILRDFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIE
NKPKKELIKVLIQRGY-----D---SDPVKAWKEAQQKVPDE--EENEESDTEKETEKSN
SVTDSGPTFNYLLD-MPLWYLTKEKKDELCRLRNEKEQELDTLKRKSPSDLWKED

ENSGT00390000016222_1_Linker_6_9 (1436, 1773)

LATFI
EELEAVEAKEKQDEQIGLPGKG---------GKAKGKKT--QM-AEVLPSPRGQRVIPRI
TIEMKAEAEKKNKKKIKNENTEGSP-------QEDGMELEGLKQRLEKK--QKRE---PG
TKTKKQTTLPFKPIKKGKKRNPWSDSESDRSS-DESNFD---VPPRETEPRRAATKTKFT
VDLDSDEDFSDFDEK-TDD---EDFVPSD-A-----SPPKTKTSPKLTNK-DLKPQK---
SAMSDLEAD--D---------AK--DSVPLSSSPPAT---HFPNETEIT-NTN----VTV
KKTAAKVSQ-------------SSTSTTGAKK

PF08070 // ENSGT00390000016222_1_Domain_9 (1773, 1882)

RAAPKG-TK-----REPALNSGVS-QKP
DPAKTK-IRRKRKPSTSDDSDSNFEKIVSKAVTSKKSRGES-DDFHMD------FDSAVA
PRAKSVR-------AKKPIKYLEESDEDDLF-------

---------MEVSPLQPVNENMQVNKIKKNEDAKKRLSIERIYQKKT-QLEHILL-----
---------RP-D-T-YI--GSVELVTQQMWVYDEDVGINYREVTFV

PF02518 // ENSGT00390000016222_1_Domain_0 (108, 255)

PGLYKIFDEILVN
AADNKQRDPKMSCIRVTIDPENNLISIWNNGKGIPVVEHKVEKMYVPALIFGQLLTSSNY
DDDEKKVTGGRNGYGAKLCNIFSTKFTVETASREYKKMFKQ--TWMDNMGRAGEMELKPF
SGEDYTCITFQPDL

ENSGT00390000016222_1_Linker_0_1 (255, 305)

SKFKMQSLDKDIVALMVRRAYDIAGSTKDVKVFLNGNKLP------
--VK

PF00204 // ENSGT00390000016222_1_Domain_1 (305, 590)

GFRSYVDMYLKDKLDETGNPLKVIHEQVNHRWEVCLTMSEKGFQQISFVNSIATS-
----------------------------------KGGRHVDYVADQIVTKLVDVVKKKNK
GGVAVKAHQVKNHMWIFVNALIENPTFDSQTKENMTL-------------------Q-P-
-K--S-F--G-S--T--C-Q--L-S--E--K------------------FIKA-------
-----------------AIGC-GIV-ES-ILN-WVK-FK-AQV-QLN-K

ENSGT00390000016222_1_Linker_1_3 (590, 632)

KC-SAV-KHN-
RIK-GIP-KLD-DAND-AGGRNSAD--C-TL

PF01751 // ENSGT00390000016222_1_Domain_3 (632, 769)

-ILT-EGD-SAK-TL-AVS-GL-GVV-GR
-DKY-GVF-PL-RGK-ILN-VR-EAS-HKQ-IME-NAE-INN-IIK-IVG-LQY-KKN-Y
ED-EDS-LKT-LRY-GKI-MI-MTD-QDQ-DGS-HIK-GL-LI-NFI-HH-NWP-SL-LR
H-RF-LEE-FI-TPIV-KVS-KNK-QEMAFYSL---PEF-EEWKSST-------PNHKKW
KVKYYKG------------------LGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAIS
LAF-SKKQIDDRKEWLTNFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNS
DNERSIPSMVDGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTII
N--LAQNFVGSNNLNLLQPIGQFGTRLHGGKDSASPRYIFTMLSSLARLLFPPKDDHTLR
FLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWSCKIPNFDVREVVNNIRRLMDGEEPLP
MLPSYKNFKGTIEELAPNQYVISGEVAILNSTTIEISELPIRTWTQTYKEQVLEPMLNGT
EKTPPLITDYREYHTD-TTVKFVVKMTEEKLAEAERVGLHKVFKLQTSLTCNSMVLFDHV
GCLKKYDTVLDILRDFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIE
NKPKKELIKVLIQRGY-----D---SDPVKAWKEAQQKVPDE--EENEESDTEKETEKSN
SVTDSGPTFNYLLD-MPLWYLTKEKKDELCRLRNEKEQELDTLKRKSPSDLWKEDLATFI
EELEAVEAKEKQDEQIGLPGKG---------GKAKGKKT--QM-AEVLPSPRGQRVIPRI
TIEMKAEAEKKNKKKIKNENTEGSP-------QEDGMELEGLKQRLEKK--QKRE---PG
TKTKKQTTLPFKPIKKGKKRNPWSDSESDRSS-DESNFD---VPPRETEPRRAATKTKFT
VDLDSDEDFSDFDEK-TDD---EDFVPSD-A-----SPPKTKTSPKLTNK-DLKPQK---
SAMSDLEAD--D---------AK--DSVPLSSSPPAT---HFPNETEIT-NTVPKKNVTV
KKTA-AKSQ-------------SSTSTTGAKK

PF08070 // ENSGT00390000016222_1_Domain_9 (1773, 1882)

RAAPKG-TK-----REPALNSGVS-QKP
DPAKTK-IRRKRKPSTSDDSDSNFEKIVSKAVTSKKSRGES-DDFHMD------FDSAVA
PRAKSVR-------AKKPIKYLEESDEDDLF-------

---------MEVSPLQPVNENMQVSKTKKNEDAKKRLSVERIYQKKT-QLEHILL-----
---------RP-D-T-YI--GSVESVTQQMWVYDEDTGINYREVTYV

PF02518 // ENSGT00390000016222_1_Domain_0 (108, 254)

PGLYKIFDEILVN
AADNKQRDPKMSCIRITIDPENNLISIWNNGKGIPVVEHKVEKMYVPALIFGQLLTSSNY
DDEEKKVTGGRNGYGAKLCNIFSTKFTVETASREYKKMFKQ--TWMDNMGKAGEMELKPF
SGEDYTCITFHPD

ENSGT00390000016222_1_Linker_0_1 (254, 305)

LSKFKMQSLDKDIVALMVRRAYDIAGSTKDVKVYLNGNRLP------
--VK

PF00204 // ENSGT00390000016222_1_Domain_1 (305, 590)

GFRSYVDLYLKDKVDETGNPLKIIHEQVNHRWEVCLTMSEKGFQQISFVNSIATS-
----------------------------------KGGRHVDYVADQIVTKLVDVVKKKNK
GGVAVKAHQVKNHMWIFVNALIENPTFDSQTKENMTL-------------------Q-V-
-K--S-F--G-S--T--C-Q--L-S--E--K------------------FIKA-------
-----------------AIGC-GIV-ES-ILN-WVK-FK-AQI-QLN-KKC-SAV-KHN-
RIK-GIP-KLD-DAND-AGGRNSTE--C-TL-ILT-EGD-SAK-TL-AVS-GL-GVV-GR
-DKY-GVF-PL-RGK-ILN-VR-EAS-HKQ-IME-NAE-INN-IIK-IVG-LQY-KKN-Y
ED-EDS-LKT-LRY-GKI-MI-MTD-QDQ-DGS-HIK-GL-LI-NFI-HH-NWP-SL-LR
H-RF-LEE-FI-TPIV-KVS-KNK-QEMAFYSL---PEF-EEWKSST-------PNHKKW
KVKYYKG------------------LGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAIS
LAF-SKKQIDDRKEWLTHFMEDRRQRKLLGLPDDYLYGQATTYLTYNDFINKELILFSNS
DNERSIPSMVDGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTII
N--LAQNFVGSNNLNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLARLLFPAKDDHTLK
FLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWSCKIPNFDVREVVNNIRRLMDGEEPLP
MLPSYKNFKGTIEELAPNQYVISGEVAILNSTTIEISELPIRTWTQTYKEQVLEPMLNGT
EKTPPLITDYREYHTD-TTVKFVVKMTEEKLAEAERVGLHKVFKLQTSLTCNSMVLFDHV
GCLKKYDTALDILRDFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIE
NKPKKELIKVLIQRGY-----D---SDPVKAWKEAQQKVPDE--EENEESDNEKQSEKSD
SATDSGPTFNYLLD-MPLWYLTKEKKDELCKLRNEKEQELETLKRKSPSDLWKEDLAAFV
EELEVVEAKEKQDEQIGLPGKG---------GKAKGKKT--QM-VEILPSPSGKRVIPRV
TEEMKAEAEKKIKKKIKSENTEGSP-------QEEGMEVESLKLRLEKK--QKRE---PV
TKTKKQTTLPFKPIKKAKKRNPWSDSESDMSS-NESNFD---VPPREKESRRAAAKTKFT
MDLDSDEDFSDFDEDT-QD----DFVPSNA------SPPKIQTSPKHSNK-ELK------
PLKSASSVTELDA--------DDAEDNVPPPPSSPAA---DFPAVTETI-NPVPKKNVTA
KKTA-AKSQ-------------SPTSTTGAKK

PF08070 // ENSGT00390000016222_1_Domain_9 (1773, 1863)

RAAPKR-TK-----KDPDLDSDVS-KKP
NAPKTK-TRRKRKPSSSDDSDSNFEKLISKAVTSKKPKEES-DDFHLD------LDSAVG
SRVQELTSASTSGTSIPPRTTWPAARPLRFYRTFCATQ

----------QASPFHPVNENMQVNKIKKNEDAKKRLSVERIYQKKT-QLEHILL-----
---------RP-D-T-YI--GSVELVTQQMWVYDEDVGINYREVTFV

PF02518 // ENSGT00390000016222_1_Domain_0 (108, 253)

PGLYKIFDEILVN
AADNKQRDPKMSCIRVTIDPENNLISIWNNGKGIPVVEHKVEKMYVPALIFGQLLTSSNY
DDDEKKVTGGRNGYGAKLCNIFSTKFTVETASREYKKMFKQ--TWMDNMGRAGEMELKPF
NGEDYTCITFQPDLSKFKMQSLDKDIVALMVRRAYDIAGSTKDVKVFLNGNKLP------
--VKGFRSYVDMYLKDKLDETGNSLKVIHEQVNHRWEVCLTMSEKGFQQISFVNSIATS-
----------------------------------KGGRHVDYVADQIVTKLVDVVKKKNK
GGVAVKAHQVKNHMWIFVNALIENPTFDSQTKENMTL-------------------Q-P-
-K--S-F--G-S--T--C-Q--L-S--E--K------------------FIKAPHLYSRF
LIDPFFPNMIPNMNLFQAIGC-GIV-ES-ILN-WVK-FK-AQV-QLN-KKC-SAV-KHN-
RIK-GIP-KLD-DAND-AGSRNSTE--C-TL-ILT-EGD-SAK-TL-AVS-GL-GVV-GR
-DKY-GVF-PL-RGK-ILN-VR-EAS-HKQ-IME-NAE-INN-IIK-IVG-LQY-KKN-Y
ED-EDS-LKT-LRY-GKI-MI-MTD-QDQ-DGS-HIK-GL-LI-NFI-HH-NWP-SL-LR
H-RF-LEE-FI-TPIV-KVS-KNK-QEMAFYSL---PEF-EEWKSST-------PNHKKW
KVKYYKG------------------LGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAIS
LAF-SKKQIDDRKEWLTNFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNS
DNE

PF00521 // ENSGT00390000016222_1_Domain_6 (964, 1435)

RSIPSMVDGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTII
N--LAQNFVGSNNLNLLQPIGQFGTRLHGGKDSASPRYIFTMLSSLARLLFPPKDDHTLK
FLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWSCKIPNFDVREIVNNIRRLMDGEEPLP
MLPSYKNFKGTIEELAPNQYVISGEVAILNSTTIEISELPIRTWTQTYKEQVLEPMLNGT
EKTPPLITDYREYHTD-TTVKFVVKMTEEKLAEAERVGLHKVFKLQTSLTCNSMVLFDHV
GCLKKYDTVLDILRDFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIE
NKPKKELIKVLIQRGY-----D---SDPVKAWKEAQQKVPDE--EENEESDNEKETEKSD
SVTDSGPTFNYLLD-MPLWYLTKEKKDELCRLRNEKEQELDTLKRKSPSDLWKE

ENSGT00390000016222_1_Linker_6_9 (1435, 1773)

D-ATFI
EEWEAVEAKEKQDEQVGLPGKG---------GKAKGKKT--QM-AEVLPSPCGQRVIPRI
TIEMKAEAEKKNKKKIKNENTEGSP-------QEDGMELEGLKQRLEKK--QKRE---PG
TKTKKQTTLPFKPIKKGKKRNPWSDSESDRSS-DESNFD---VPPRETEPRRAATKTKFT
MDLDSDEDFSDFDEK-TDE---EDFVPSD-A-----SPPKTKTSPKLTNK-ELKPQK---
SAVSDLEAD--D---------AK--DSIPLSSSPPAT---RFPDETEIT-NPVPKKNVTV
KKTA-AKSQ-------------SSTSTTGAKK

PF08070 // ENSGT00390000016222_1_Domain_9 (1773, 1883)

RAAPKG-TK-----RDPALNSGVS-QKP
DPAKTK-NRRKRKPSTSDDSDSNFEKIVSKAVTSKKSKGES-DDFHMD------FDSAVA
PRAKSVR-------AKKPIKYLEESDEDDLF-------

------------------------------------------------------------
--------------------------SQQMWVFDEGVGLNCRDVTFV

PF02518 // ENSGT00390000016222_1_Domain_0 (108, 209)

PGLYKIFDEILVN
AADNKQRDKNMSCIKVTIDVENNTISVWNNGKGIPVVEHKVEKVYVPAMIFGQLLTSSNY
DDNEKKVTGGRNGYGAKLCNIFSTKFTVETGCREYKKLFKQ-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

---------MEVSPLQPVNENMQINKIKKNEDAKKRLSIERIYQKKT-QLEHILL-----
---------RP-D-T-YI--GSVELVTQQLWVYDEDIGINYREVTFV

PF02518 // ENSGT00390000016222_1_Domain_0 (108, 253)

PGLYKIFDEILVN
AADNKQRDPKMSCIRVTIDPENNLISIWNNGKGIPVVEHKVEKVYVPALIFGQLLTSSNY
DDKEKKVTGGRNGYGAKLCNIFSTKFTVETASREYKKMFKQ--TWMDNMGKAGEMELKPF
NGEDYTCITFQP

ENSGT00390000016222_1_Linker_0_1 (253, 305)

DLSKFKMQSLDKDIVALMVRRAYDVAGSTKDVKVFLNGNKLP------
--IK

PF00204 // ENSGT00390000016222_1_Domain_1 (305, 590)

GFRSYVDMYLKDKVDETGNPLKIIHEQVNHRWEVCLTMSEKGFQQISFVNSIATS-
----------------------------------KGGRHVDYVADQIVTKLVDVVKKKNK
GGVAVKAHQVKNHMWIFVNALIENPTFDSQTKENMTL-------------------Q-A-
----K-F--G-S--T--C-Q--L-S--E--K------------------FIKA-------
-----------------AIGS-GIV-ES-ILN-WVK-FK-AQV-QLN-KKC-SAV-KHN-
RIK-GIP-KLD-DAND-AGGRNSTE--C-TL-ILT-EGD-SAK-TL-AVS-GL-GVV-GR
-DKY-GVF-PL-RGK-ILN-VR-EAS-HKQ-IME-NAE-INN-IIK-IVG-LQY-KKN-Y
ED-EDS-LKT-LRY-GKI-MI-MTD-QDQ-DGS-HIK-GL-LI-NFI-HH-NWP-SL-LR
H-RF-LEE-FI-TPIV-KVS-KNK-QEMAFYSL---PEF-EEWKSST-------PNHKKW
KVKYYKG------------------LGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAIS
LAF-SKKQTDDRKEWLTHFMEDRRQRKLLGLPEDYLYGQATTYLTYNDFINKELILFSNS
DNERSIPSMVDGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTII
N--LAQNFVGSNNLNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLARLLFPPKDDHTLK
FLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWSCKIPNFDVREVVNNIRRLMDGEEPLP
MLPSYKNFKGTIEELASNQYVISGEVAILNSTTIEISELPIRTWTQTYKEQVLEPMLNGT
EKMPPLITDYREYHTD-TTVKFVVKMTEEKLAEAERVGLHKVFKLQTSLTCNSMVLFDHV
GCLKKYDTVLDILKDFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIAGKIIIE
NKPKKELIKVLIQRGY-----D---SDPVKAWKEAQQKIPDE--EENEESDNEKDTEKSD
SVADSGPTFNYLLD-MPLWYLTKEKKDELCKLRNEKEQELETLKKKSPSDLWKEDLAAFI
EELEVVEAKEKQDEQIGLPGKG---------GKAKGKKT--QM-AEVLPSPSGKRVIPRV
TLEMKAEAEKKIKRKIKNENTEGSP-------QEDGVEPESLKQRLEKK--QKRE---PS
TKTKKQTTLPFKPIKKGKKKNPWSDSESDMSD-DESNFD---VPPRETEPRRVATKNKFT
MDLDSDEDFSDFDEKT-DD---EDFIPSDA------SPPKTKTSPKSTNK-ELKSQKSAM
SVMQ------QDD--------D-ATKNYSVSSNGRNC-IIDVEAVATYVSSTKKKKTIFL
KRDE-GESQ-------------SSTSTAA

PF08070 // ENSGT00390000016222_1_Domain_9 (1770, 1883)

TKKRAAAKGGAK-----KDP----GIS-QKP
VPAKTK-NPRKRKPSTSDDSDSNFEKMISKAATSKKSKGES-EDFHLD------LDSAVA
PRAKSGR-------ARKPIKYLEESDEDDLF-------

---------MEVSPLQPVNENMQMNKIKKNEDAKKRLSIERIYQKKT-QLEHILL-----
---------RP---DTYI--GSVELVTQQMWVYDEDIGMNYREVTFVPGLYKIFDEILVN
AADNKQRDPKMSCIRVTIDPYRI---NYTRGSGDPVNDDILECSS---GLYSIIF-----
--LISLFIGGRNGYGAKLCNIFSTKFTVETASKEYKKMFKQ--TWMDNMGRAGEMELKPF
SGEDYTCITFQPDLSKFKMQNLDKDIVALMVRRAYDIAGSTKDVKVFLNGNKLP------
--VKGFRSYVDMYLKDKLDETGNPLKVIHEQVNHRWEVCLTMSEKGFQQISFVNSIATS-
----------------------------------KGGRHVDYVADQIVAKLADVVKKKNK
GGVAVKAHQVKNHMWIFVNALIENPTFDSQTKENMTLQAKS-------------------
------F--G-----STCQL--------------------------SEKFIKA-------
-----------------ATGC-GIV-ES-ILN-WVK-FK-AQV-QLN-KKC-SAV-KHN-
RIK-GIP-KLD-DAND-AGSRNSAE--C-TL

PF01751 // ENSGT00390000016222_1_Domain_3 (632, 769)

-ILT-EGD-SAK-TL-AVS-GL-GVV-GR
-DKY-GVF-PL-RGK-ILN-VR-EAS-HKQ-IME-NAE-INN-IIK-IVG-LQY-KKN-Y
ED-EDS-LKT-LRY-GKI-MI-MTD-QDQ-DGS-HIK-GL-LI-NFI-

ENSGT00390000016222_1_Linker_3_5 (769, 790)

HH-NWP-SL-LR
H-RF-LEE-

PF16898 // ENSGT00390000016222_1_Domain_5 (790, 962)

FI-TPIV-KVS-RNK-QELAFYSL---PEF-EEWKGST-------PNHKKW
KVKYYKG------------------LGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAIS
LAF-SKKQTDDRKEWLTHFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNS
DNERSIPSMVDGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTII
N--LAQNFVGSNNLNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLARLLFPPRDDHTLR
FLYDDNQRVEPEWYIPIIPMVLVNGAEGIGTGWSCKIPNFDVREVVNNIRRLMDGEEPLP
MLPSYKNFKGTIEELAPNQYVINGEIAILNSTTIEISELPVRTWTQTYKEQVLEPMLNGT
EKTPPLITDYREYHTD-TTVKFVVKMTEEKLAQAESAGLHKVFKLQTSLTCNSMVLFDHV
GCLKKYDTVLDILRDFFELRLKYYGLRKEWLLGMLGAESSKLNNQARFILEKIDGKIIIE
NKPKKELIKVLIQRGY-----D---SDPVKAWKEAQQKAPDD--EENEESDSEREAAKGD
SAADTGPTFNYLLD-MPLWYLTKEKKDELCRQRSEKEQELDTLKKKSPSDLWKEDLAAFI
EELEAVEAKEKQDEQAGLPGKG---------AKAKGKKA--HL-AEVLPSQQGTRVIPRV
TVEMKAEAEKKTRKKVKSENTDGTP-------AEDGVELESLKQRLEKK--QKKE---LG
TKAKKQTTLPFKPIKKGKKRNPWSDSESDMSS-AESNFD---VPAREVEPRRAAAKTKFT
MDLDSEDDFSDFDEKVED----DDFVPSG-A-----SPPEAKTLPKLTKK-EPKPQKSTV
SGTYL-----I------------KIDGAPASSSPPA----DFPTGSDVT-KPPPERSIPV
KKRAAKGP--------------PSASAAGARK

PF08070 // ENSGT00390000016222_1_Domain_9 (1773, 1882)

RAAPKG-AK-----RAPASKPEAS-EKP
DPARAK-NQRKRKPSDS-DSDSNFEEVIPKGAISKKPKAES-GGFHA----------ALE
PRAKSGR-------ARKPIKYLEESDEDDLF-------

----------------PVNENMQINKIKKNEDAKKRLSIERIYQKKT-QLEHILL-----
---------RP-D-T-YI--GSVELVTQXXXXXXXXXXXXXXXXXXXX

PF02518 // ENSGT00390000016222_1_Domain_0 (109, 255)

XXXXXXXXXXXN
AADNKQRDPKMSCIRVTIDPENNLISIWNNGKGIPVVEHKVEKMYVPALIFGQLLTSSNY
DDDEKKVTGGRNGYGAKLCNIFSTKFTVETACREYKRMFKQA-TWMDNMGSAGEMELKPF
NGEDYTCITFQPDLSKFKMQSLDKDIVALMVRRAYDIAGSTKDVKVFLNGNKLP------
--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------X-----XX--X-XX--XX---
------------------------------------XXXXXXXX--XX--XX--------
-XXXX-XX-X-XXXXXXX------------------------------------------
-------------------------------------------------XXXXXXXXXXX
XXXXXXXXXXXXXXXXXAIGC-GIV-ES-ILN-WVK-FK-AQV-QLN-KKC-SAV-KHN-
RIK-GIP-KLD-DAND-AGGRNSAE--C-TL-ILT-EGD-SAK-TL-AVS-GL-GVV-GR
-DKY-GVF-PL-RGK-ILN-VR-EAS-HKQ-IME-NAE-INN-IIK-IVG-LQY-KKN-Y
ED-EDS-LKT-LRY-GKI-MI-MTD-QDQ-DGS-HIK-GL-LI-NFI-HH-NWP-SL-LR
H-RF-LEE-FI-TPIV-KVS-KNK-QEIAFYSL---PEF-EEWKSST-------PNHKKW
KVKYYKG------------------LGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAIS
LAF-SKKQIDDRKEWLTHFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNS
DNE

PF00521 // ENSGT00390000016222_1_Domain_6 (964, 1448)

RSIPSMVDGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTII
N--LAQNFVGSNNLNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLARLLFPPKDDHTLK
FLYDDNQRVEPEWYIPIIPMVLVNGAEGIGTGWSCKIPNFDVREVVNNIRRLMDGEELLP
MLPSYKNFKGTIEELAPNQYVISGEVAILNSTTIEISELPIRTWTQTYKEQVLEPMLNGT
EKTPPLITDYKEYHTD-TTVKFVVKMTEEKLAEAERVGLHKVFKLQTSLTCNSMVLFDHV
GCSKKYDTVLDILRDFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIE
NKPKKELIKVLIQRGY-----D---SDPVKAWKEAQQKVPDE--EENEESDNEKETEKTD
SVTDSGPTFNYLLD-MPLWYLTKEKKDELCKLRNEKEQELDTLKRKSPSDLWKEDLAAFI
EELEAVE

ENSGT00390000016222_1_Linker_6_9 (1448, 1773)

AKEKQDEQIGLPGKG---------GKGKGKKT--QV-AEVLPSPRGKRVIPRV
TIEMKAEAEKKIKKKIKSENTEGSP-------QEDGVELEGLKQRIEKK--QRRE---PG
TKTKKQSTLPFKPIKKGKKKNPWSDSESDMSS-SESNFD---VPPRETEPRRAAAKTKFT
MDLDSDDDFSDFDENS-ED---EDFVPSD-A-----SPPKTKTSQKTCNK-ESKPLKSTM
--------SDLEV--------DDAKNSVPVSSSLPAT---DSPAETEII-NPASKKNVTV
KKTAAK-SQ-------------SSTSTTGAQK

PF08070 // ENSGT00390000016222_1_Domain_9 (1773, 1883)

RAAPKG-TK-----RDPTLKSDAS-QKP
EPAKTK-NRRKRQSSTSDDSDSNFGXXXXXXXXXXKSKREN-DDFHVD--------SAVS
PRAKSGR-------SKKPIKYLEESDEDDLF-------

---------MEVSPLQPVNENMQVNKIKKNEDAKKRLSIERIYQKKT-QLEHILL-----
---------RP-D-T-YI--GSVELVTQQMWVYDEDVGINYREVTFV

PF02518 // ENSGT00390000016222_1_Domain_0 (108, 255)

PGLYKIFDEILVN
AADNKQRDPKMSCIRVTIDPENNLISIWNNGKGIPVVEHKVEKMYVPALIFGQLLTSSNY
DDDEKKVTGGRNGYGAKLCNIFSTKFTVETASREYKKMFKQ--TWMDNMGRAGEMELKPF
SGEDYTCITFQPDL

ENSGT00390000016222_1_Linker_0_1 (255, 305)

SKFKMQSLDKDIVALMVRRAYDIAGSTKDVKVFLNGNKLP------
--VK

PF00204 // ENSGT00390000016222_1_Domain_1 (305, 590)

GFRSYVDMYLKDKLDETGNPLKVIHEQVNHRWEVCLTMSEKGFQQISFVNSIATS-
----------------------------------KGGRHVDYVADQIVTKLVDVVKKKNK
GGVAVKAHQVKNHMWIFVNALIENPTFDSQTKENMTL-------------------Q-P-
-K--S-F--G-S--T--C-Q--L-S--E--K------------------FIKA-------
-----------------AIGC-GIV-ES-ILN-WVK-FK-AQV-QLN-K

ENSGT00390000016222_1_Linker_1_3 (590, 632)

KC-SAV-KHN-
RIK-GIP-KLD-DAND-AGGRNSTD--C-TL

PF01751 // ENSGT00390000016222_1_Domain_3 (632, 757)

-ILT-EGD-SAK-TL-AVS-GL-GVV-GR
-DKY-GVF-PL-RGK-MLN-VR-EAS-HKQ-IME-NAE-INN-IIK-IVG-LQY-KKN-Y
ED-EDS-LKT-LRY-GKI-MI-MTD-QEQ-DGS-HIK-GF------------WP-LF-CD
T-RF-LEE-SYQLPYV-KCA--NA-TVHCFYHRSLPLNL-KNVKSLT-------PKYKKW
KVQILQRLYEGT------WYSCFYRFGYSTSKEAKEYFSN----------FCPEDDAAIS
LAF-SKKQIDDRKEWLTNFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNS
DNERSIPSMVDGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTII
N--LAQNFVGSNNLNLLQPIGQFGTRLHGGKDSASPRYIFTMLSSLARLLFPPKDDHTLK
FLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWSCKIPNFDVREVVNNIRRLMDGEEPLP
MLPSYKNFKGTIEELAPNQYVISGEVAILNSTTIEISELPIRTWTQTYKEQVLEPMLNGT
EKTPPLITDYREYHTD-TTVKFVVKMTEEKLAEAERVGLHKVFKLQTSLTCNSMVLFDHV
GCLKKYDTVLDILRDFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIE
NKPKKELIKVLIQRGY-----D---SDPVKAWKEAQQKVPDE--EENEESDNEKETEKSD
SVTDSGPTFNYLLD-MPLWYLTKEKKDELCRLRNEKEQELDTLKRKSPSDLWKEDLATFI
EELEAVEAKEKQDEQVGLPGKA---------GKAKGKKT--QM-AEVLPSPRGQRVIPRI
TIEMKAEAEKKNKKKIKNENTEGSP-------QEDGMELEGLKQRLEKK--QKRE---PG
TKTKKQTTLPFKPIKKGKKRNPWSDSESDRSS-DESNFD---VPPRETEPRRAATKTKFT
VDLDSDEDFSDFDEK-TDD---EDFVPSD-A-----SPPKTKTSPKLTNK-DLKPQK---
SAMSDLEAD--D---------AKDSDSVPLSSSPPAT---HFPNETEIT-NTVPKKNVTV
KKTAA-KSQ-------------SSTSTTGAKK

PF08070 // ENSGT00390000016222_1_Domain_9 (1773, 1882)

RAAPKG-TK-----REPALNSGIS-QKP
DPAKTK-IRRKRKPSTSDDSDSNFEKIVSKAVTSKKSRGES-DDFHMD------FNSAVA
PRAKSVR-------AKKPIKYLEESDEDDLF-------

---------MELSPLQPVNENMQMNK-KKNEDGKKRMSIERIYQKKT-QLEHILL-----
---------RP-D-T-YI--GSVELVTQQMWVYDEDVGINYREVTFV

PF02518 // ENSGT00390000016222_1_Domain_0 (108, 255)

PGLYKIFDEILVN
AADNKQRDPKMSCIRVTIDPENNLISIWNNGKGIPVVEHKVEKMYVPALIFGQLLTSSNY
DDDEKKVTGGRNGYGAKLCNIFSTKFTVETASREYKKMFKQ--TWMDNMGRAGEMELKPF
NGEDYTCITFQPDLSKFKMQSLDKDIVALMVRRAYDVAGSTKDVKVFLNGNRLP------
--VKGFRSYVDMYLKDKLDETGNALKVVHEQVNPRWEVCLTMSEKGFQQISFVNSIATS-
----------------------------------KGGRHVDYVADQIVSKLVDVVKKKNK
GGVAVKAHQVKNHMWIFVNALIENPTFDSQTKENMTL-------------------Q-A-
-K--S-F--G-S--T--C-Q--L-S--E--K------------------FIKA-------
-----------------AIGC-GIV-ES-ILN-WVK-FK-AQI-QLN-KKC-SAV-KHN-
RIK-GIP-KLD-DAND-AGSRNSTE--C-TL

PF01751 // ENSGT00390000016222_1_Domain_3 (632, 769)

-ILT-EGD-SAK-TL-AVS-GL-GVV-GR
-DKY-GVF-PL-RGK-ILN-VR-EAS-HKQ-IME-NAE-INN-IIK-IVG-LQY-KKN-Y
ED-EDS-LKT-LRY-GKI-MI-MTD-QDQ-DGS-HIK-GL-LI-NFI-

ENSGT00390000016222_1_Linker_3_5 (769, 790)

HH-NWP-SL-LR
H-RF-LEE-

PF16898 // ENSGT00390000016222_1_Domain_5 (790, 962)

FI-TPIV-KVS-KNK-QEMAFYSL---PEF-EEWKSST-------PNHKKW
KVKYYKG------------------LGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAIS
LAF-SKKQVDDRKEWLTHFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNS
DNERSIPSMVDGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTII
N--LAQNFVGSNNLNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLTRLLFPPKDDHTLK
FLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWSCKIPNFDVREVVNNIRRLLDGEEPLP
MLPSYKNFKGTIEELASNQYVINGEVAILNSTTIEISELPVRTWTQTYKEQVLEPMLNGT
EKTPPLITDYREYHTD-TTVRFVIKMTEEKLAEAERVGLHKVFKLQTSLTCNSMVLFDHV
GCLKKYDTVLDILKDFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIE
NKPKKELIKVLIQRGY-----D---SDPVKAWKEAQQKVPDE--EENEES----DNENSD
SVPESGPTFNYLLD-MPLWYLTKEKKDELCKQRNEKEQELNTLKKKSPSDLWKEDLAVFI
EELEVVEAKEKQDEQVGLPGKG---------GKAKGKKG--QV-SEVLPSPGGKRVIPHV
TMEMKAEAEKKIRKKIKSENAEGTP-------AEDGLELGGLKQRLAKK--QKKE---PD
TMAKKQTTLPFKPIKKGKKRNPWSDSESDMSS-NESNFD---VPPREKDPRRAATKAKFT
VDLDSDEDFSGFEEKD-ED---EDFFPLD-T-----SPPKTKIPPKNRTK-TLKTQKSTT
SVA------DLE---------SDVQDSVPASPSPPA---ADVPAEKEQL-KLSSKQTAAA
KKTVTKSQS-------------STS-TAGTKK

PF08070 // ENSGT00390000016222_1_Domain_9 (1773, 1882)

RAAPKA-TK-----SDSTLSVHGP-EKP
DPAKAK-STRKRKQSSSDDSDSDFEKVVSKAATSKKLKGET-QDFHVD------LDETVA
PRAKSGR-------ARKPIKYLEESDEDD----LF---

---------------------MQMNK-KKNEDAKKRLSIERIYQKKT-QLEHILL-----
---------RP-D-T-YI--GSVELVTQV-------------------------------
----K

PF02518 // ENSGT00390000016222_1_Domain_0 (126, 255)

IKDPKMSCIRVTIDPENNLISIWNNGKGIPVVEHKVEKMYVPALIFGQLLTSSNY
DDDEKKVTGGRNGYGAKLCNIFSTKFTVETASTEYKKMFKQ--TWMDNMGKAGEMELKPF
SGDDYTCITFQPDLSKFKMQSLDKDIVALMVRRAYDIAGSTKDVKVFLNGNKLP------
--VKGFRSYVDMYLKDKLDETGNPLKVIHEQVNQRWEVCLTMSEKGFQQISFVNSIATS-
----------------------------------KGGRHVDYVADQIVSKLADVVKKKNK
GGVAVKAHQVKNHMWIFVNALIENPTFDSQTKENMTL-------------------Q-A-
-K--S-F--G-S--T--C-L--L-S--E--K------------------FIKA-------
-----------------AIGC-GIV-ES-ILN-WVK-FK-AQV-QLN-KKC-SAV-KHN-
RIK-GIP-KLD-DAND-AGSRNSTE--C-TL

PF01751 // ENSGT00390000016222_1_Domain_3 (632, 769)

-ILT-EGD-SAK-TL-AVS-GL-GVV-GR
-DKY-GVF-PL-RGK-LLN-VR-EAS-HKQ-IME-NAE-INN-IIK-IVG-LQY-KKN-Y
ED-EDS-LKT-LRY-GKI-MI-MTD-QDQ-DGS-HIK-GL-LI-NFI-HH-NWP-SL-LR
H-RF-LEE-FI-TPIV-KVS-KNK-QEIAFYSL---PEF-EEWKSST-------QNHKKW
KVKYYKG------------------LGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAIS
LAF-SKKQVDDRKEWLTNFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNS
DNE

PF00521 // ENSGT00390000016222_1_Domain_6 (964, 1436)

RSIPSMVDGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTII
N--LAQNFVGSNNLNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLARLVFPPKDDHTLK
FLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWSCKIPNFDVREVVNNIRRLMDGEEPLP
MLPSYKNFKGTIEELASNQYVINGEVAILNSTTIEISELPIRTWTQTYKEQVLEPMLNGT
EKTPPLITDYREYHTD-TTVKFVVKMTEEKLAEAERVGLHKVFKLQTSLTCNSMVLFDHV
GCLKKYDTVLDILRDFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIVIE
NKPKKELIKVLIQRGY-----D---SDPVKAWKEAQQKIPEE--EENEDSDNEN-SEKSD
SVTDSGPTFNYLLD-MPLWYLTKEKKDELCKQRNEKEQELDTLKRKSPSDLWKED

ENSGT00390000016222_1_Linker_6_9 (1436, 1771)

LAAFI
DELEAVEAKEKQDQQVGLSGKG---------GKAKGKKM--QM-AEALPSPQGKRVIPQV
TMEMKAGAEKKIKKKIKSENTEGMS-------NEDGMELEGLKQRIQKK--QKKE---PA
FL-----------------------------------------------PLPSKSKTKYT
MDLDSDKEFSDFSEKD-QD---KDFLPSDP------SPPKTETPQK-NIK-KVKPQKSTM
SVSI------LRH--------RPS--------WDTQV-HVDFNLEC--IIQE-------L
HWKINLRGQ-------------SSTSTAVT

PF08070 // ENSGT00390000016222_1_Domain_9 (1771, 1882)

KKRAEPKGV-K-----SQSTLKSDVP-QKP
NPAKPK-NQRKRKPSTSDDSDSNFEKLVSKAHTSKKPKGES-EDFHLD------VDPSVA
PRAKSVR-------AKKPIKYLEESDEDDLF-------

-----MELSQSPSPLRPADENIRLN---KADGP-KKLSVEHIYQKKT-QLEHILL-----
---------RP---DTYI--GSVELVTQQMWVYDEGVGLNCRDVTFV

PF02518 // ENSGT00390000016222_1_Domain_0 (108, 254)

PGLYKIFDEILVN
AADNKQRDKNMSCIKVTLDVENNTISVWNNGKGIPVVEHKVEKVYVPALIFGQLLTSSNY
DDNEKKVTGGRNGYGAKLCNIFSTKFTVETGCREYKKLFKQ--TWTDNMGKAGEMKLKYF
DGDDYTCVTFQPD

ENSGT00390000016222_1_Linker_0_1 (254, 305)

LSKFKMTILDKDIVALMSRRAYDIAGSTKDVKVFLNGQRLP------
--VK

PF00204 // ENSGT00390000016222_1_Domain_1 (305, 590)

GFRSYVDLYLKDKVDETGNALKVIHEEVNSRWEVCLTLSEKGFQQVSFVNSIATT-
----------------------------------KGGRHVDYVADQLVTKLIDVVKKKNK
NGVGVKPFQVKNHMWIFVNALIENPTFDSQTKENMTLQSKNFG-----------------
---------------STCKL--------------------------SEKFI-----KG--
----------------AI-GC-GIV-ES-ILN-WVK-FK-AQN-QLN-KKC-SAV-KHS-
KIK-GVP-KLD-DAND-AGS-KNS-LDC-TL-ILT-EGD-SAK-TL-AVS-GL-GVV-GR
-DKY-GVF-PL-RGK-ILN-VR-EAS-HKQ-IME-NAE-INN-IIK-IVG-LQY-KKN-Y
ED-QES-LKT-LRY-GKI-MI-MTD-QDQ-DGS-HIK-GL-LI-NFI-HH-NWP-SL-LR
H-NF-LEE-FIT-PII-KAT-KNK-EEI-AF-YSI-PEF-EEW-KTS-T-----QNYNSW
KIKYYKG------------------LGTSTSKEAKEYFADMARHRIGFKYSGPEDDAAIT
LAF-SKKKIEERKEWLTNFMEDRRQRKLHGLPEDYLYGKNTDYLTYNDFINKELVLFSNS
DNERSIPSLVDGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEAALMMTII
N--LAQNFVGSNNLNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLARLVFPPMDDNILK
FLYDDNQRVEPEWYMPIIPMVLVNGAEGIGTGWACKIPNFDIREVVNNIRRLMDGEEPLP
MLPSYKNFKGTIDELGPNQYVISGEVSILDSTTIEITELPVRTWTQTYKEQVLEPMLNGT
EKTPPLITDYKEYHTD-TTVRFVVKMAEDKLAEAEAVGLHKVFKLQTSLTCNSMVLFDHV
GFLKKYDSPQDILKEFFELRLRYYTLRKEWLIGMLGAESAKLSNQARFILEKIDGKIVIE
NKPKKELIQVLIQRGY-----E---SDPVKAWKEAQNKDEEE--EEEEEQE-----NDKE
PAAASGPDFNYLLN-MPLWYLTKEKKDELCKQRDNKEKELENLKCKSASDLWKEDLAAFI
EELDVVEAKQAQDESAGIVGKPLKMKGG----KAKVKKT--QL-AEVMPSPHGIRVVPRI
TAEMKAEAEKKTKKKVKSEKTEFDENQDEN--TSGEKESAGLKQRLVQKVKAEQ-----G
AK--RQATLPFKPLKKTKKRNPWSDSGSDSEESD-FEPLP----QRERVVRQAAAKVKPM
VILDSN--PSSSDEESEFQGDSEGNSEPDTN-SKKKAPPKPKPAPKETTEKAAKAPKQK-
AVPSAVP--VQDV----P------K----DKVSQD-PPAPSVPVPS--T-KAVPKKPAAA
K--KAGAT--------K--DNQPSIMDILAKKKAAPKAK

PF08070 // ENSGT00390000016222_1_Domain_9 (1780, 1883)

PAA-KEGPQCAE--------G
DNAKGRKVMKRQPSCLDSDSDSDFGSKPAKSVASKKSKLQDN-TFTVD---SDDKSPVPQ
PRARPGR-------LKKPVQYLEE----SSEDDIF---

---------MEVSPLQPVNENMQISKTKKNEDAKKRLSIERIYQKKT-QLEHILL-----
---------RP-D-T-YI--GSVELVTQHMWVYDEDIGINYREVTFV

PF02518 // ENSGT00390000016222_1_Domain_0 (108, 253)

PGLYKIFDEILVN
AADNKQRDPKMSCIRVTIDPENNLISIWNNGKGIPVVEHKVEKMYVPALIFGQLLTSSNY
DDDEKKVTGGRNGYGAKLCNIFSTKFTVETASREYKKMFKQ--TWMNNMGRAGEMELKPF
NGEDYTCITFQP

ENSGT00390000016222_1_Linker_0_1 (253, 305)

DLSKFKMQSLDKDIVALMVRRAYDIAGSTKDVKVFLNGNKLP------
--VK

PF00204 // ENSGT00390000016222_1_Domain_1 (305, 590)

GFRSYVDMYLKDKVDETGNPLKVIHEQVNPRWEVCLTMSEKGFQQISFVNSIATS-
----------------------------------KGGRHVDYIADQIVTKLVDVVKKKNK
GGVAVKAHQVKNHMWIFVNALIENPTFDSQTKENMTL-------------------Q-V-
-K--S-F--G-S--T--C-L--L-S--E--K------------------FIKA-------
-----------------AIGC-GIV-ES-ILN-WVK-FK-AQI-QLN-KKC-SAV-KHN-
RIK-GIP-KLD-DAND-AGGRNSNE--C-TL-ILT-EGD-SAK-TL-AVS-GL-GVV-GR
-DKY-GVF-PL-RGK-ILN-VR-EAS-HKQ-IME-NAE-INN-IIK-IVG-LQY-KKN-Y
ED-EDS-LKT-LRY-GKI-MI-MTD-QDQ-DGS-HIK-GL-LI-NFI-HH-NWP-SL-LR
H-RF-LEE-FI-TPIV-KVS-KNK-QEMAFYSL---PEF-EEWKSST-------PNHKKW
KVKYYKG------------------LGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAIS
LAF-SKKQIDDRKEWLTHFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNS
DNERSIPSMVDGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTII
N--LAQNFVGSNNLNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLARLLFPPKDDHTLK
FLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWSCKIPNFDIREVVNNIRRLMDGEEPLP
MLPSYKNFKGTIEELAPNQYVISGEVAILNSTTIEISELPIRTWTQTYKEQVLEPMLNGT
EKTPPLITDYREYHTD-TTVKFVVKMTEEKLAEAERVGLHKVFKLQTSLTCNSMVCLFF-
--------------FFFKKRIIISGLGKRLLCKPGCIDLFKLL---------NSYDFLIE
NK

PF00521 // ENSGT00390000016222_1_Domain_8 (1323, 1436)

PKKELIKVLIQRGY-----D---SDPVKAWKEAQQKVPDE--EENEESDNENEAEKSD
SVRDSGPTFNYLLD-MPLWYLTKEKKDELCKLRNEKEQELETLKRKSPSDLWRED

ENSGT00390000016222_1_Linker_8_9 (1436, 1774)

LAAFI
EELEAVETKEKQEEQIGLPGKG---------GKAKGKKT--QM-AEVLPSPCGKRVIPRV
TVEMKAEAEKKIKKKIKNENTEGNP-------PEDSIEPEGLKQRLEKK--QKRE---PG
TKTKKQTTLSFKPIKKGKKRNPWSDSESDMSS-NESNFD---VPPREIEPRRAATKTKFT
VDLDSDDDFSDFDEKT-QD---EDFVPSSDV-----SPLKTKASPK-HAT-K----ELKP
QKSATSEVMDVDA--------DDAKDSVLLPPGSPAA---DFSTETEIL-NPVAKKKVVV
KKIA-AKSQ-------------SSTSTKGAKKG

PF08070 // ENSGT00390000016222_1_Domain_9 (1774, 1883)

AAPKG-TK-----KDPGLNSDVP-QKP
DPPKTK-TRRKRKPSTSDDSDSNFEKMISKTVTNKKSKAES-EDFHLD------LDSAVA
PRAKSGR-------AKKPIKYLEESDEDDLF-------

---------MEVSPLQPINENMQVNKIKKNEDAKKRLSIERIYQKKT-QLEHILL-----
---------RP-D-T-YI--GSVELVTQQMWVYDEDIGMNYREVTFV

PF02518 // ENSGT00390000016222_1_Domain_0 (108, 255)

PGLYKIFDEILVN
AADNKQRDPKMSCIRVTIDPENNLISIWNNGKGIPVVEHKVEKVYVPALIFGQLLTSSNY
DDDEKKVTGGRNGYGAKLCNIFSTKFTVETASREYKKMFKQ--TWMDNMGRAGEMELKPF
NGEDYTCITFQPDLSKFKMQSLDKDIVALMVRRAYDIAGSTKDVKVFLNGIKLP------
--VKGFRSYVDMYLKDKLDETGNPLKVIHEQVNHRWEVCLTMSEKGFQQISFVNSIATS-
----------------------------------KGGRHVDYVADQIVAKLVDVVKKKNK
GGVAVKAHQVKNHMWIFVNALIENPTFDSQTKENMTL-------------------Q-A-
-K--S-F--G-S--T--C-Q--L-S--E--K------------------FIKA-------
-----------------AIGC-GIV-ES-ILN-WVK-FK-AQV-QLN-KKC-SAV-KHN-
RIK-GIP-KLD-DAND-AGSRNSTE--C-TL

PF01751 // ENSGT00390000016222_1_Domain_3 (632, 769)

-ILT-EGD-SAK-TL-AVS-GL-GVV-GR
-DKY-GVF-PL-RGK-ILN-VR-EAS-HKQ-IME-NAE-INN-IIK-IVG-LQY-KKN-Y
ED-EDS-LKT-LRY-GKI-MI-MTD-QDQ-DGS-HIK-GL-LI-NFI-HH-NWP-SL-LR
H-RF-LEE-FI-TPIV-KVS-KNK-QEIAFYSL---PEF-EEWKSST-------PNHKKW
KVKYYKG------------------LGTSTSKEAKEYFADMKRHRIQFKYTGPEDDAAIS
LAF-SKKQIDDRKEWLTHFMEDRRQRKLLGLPEDYLYGQATTYLTYNDFINKELILFSNS
DNE

PF00521 // ENSGT00390000016222_1_Domain_6 (964, 1436)

RSIPSMVDGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTII
N--LAQNFVGSNNLNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLARLLFPPKDDHTLK
FLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWSCKIPNFDVREVVNNIRRLMDGEEPLP
MLPSYKNFKGTIEELAPNQYVINGEIAILNSTTIEISELPIRTWTQTYKEQVLEPMLNGT
EKTPPLITDYREYHTD-TTVKFVVKMTEGKLAEAERVGLHKVFKLQTSLTCNSMVLFDHV
GCLKKYDTVLDILRDFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIE
NKPKKELIKVLIQRGY-----D---SDPVKAWKEAQQKVPDE--EENEESDNEKEAEKSD
SVTDSGPTFNYLLD-MPLWYLTKEKKDELCKQRNEKEQELDSLKRKSPSDLWKED

ENSGT00390000016222_1_Linker_6_9 (1436, 1773)

LAAFI
EELEAVEAKEKQDEQVGLPGKG---------GKAKGKKA--QM-TEVLPSPRGKRVIPRV
TEEMKAEAEKKIKKKIKSENPEGIS-------KEDGIEPDGLKQRLEKK--LKKE---PG
TKAKKQTTLTFKPVKKGKKRNPWSDSESDMSS-TESNFD---VPPRETEPRRAAAKTKFT
MDLDSDEDFSDFDEK-SED---EDFVPSD-A-----SPPKTKTSPKHTEK-ELKPQK---
DTVSVIDLD--DD--------DDTKDSVPSSSSPPVA---DLPVETEMK-KPSSKKNVTV
KKTTT-NSQ-------------SSTSTTGPKK

PF08070 // ENSGT00390000016222_1_Domain_9 (1773, 1882)

RAAPKG-TK-----KDPNLNSDVS-QKP
EPAKTK-NRRKRKPSTSDDSDSNFEKVISKAAASKKPKGES-DDFHLD------LDSAVA
PRAKSGR-------AKKPIKYLEESDDDDLF-------

---------MEVSPLQPVNENMQIDKIKKNGDAKKRLSIERIYQKKT-QLEHILL-----
---------RP-D-T-YI--GSVELVTQQMWVYDEDVGINYREVTFV

PF02518 // ENSGT00390000016222_1_Domain_0 (108, 253)

PGLYKIFDEILVN
AADNKQRDPKMSCIRVTIDSENNLISIWNNGKGIPVVEHKVEKMYVPALIFGQLLTSSNY
DDDEKKVTGGRNGYGAKLCNIFSTKFTVETASREYKKMFKQ--TWKDNMGRSGEMELKPF
NGEDYTCITFQPDLSKFKMQSLDKDIVALMVRRAYDIAGSTKDVKVFLNGNKLP------
--VKGFRSYVDMYLKDKVDETGNPLKVIHEQVNQRWEVCLTMSEKGFQQISFVNSIATS-
----------------------------------KGGRHVDYVADQIVTKLVDVVKKKNK
GGVAVKAHQVKNHMWIFVNALIENPTFDSQTKENMTL-------------------Q-A-
-K--S-F--G-S--T--C-Q--L-S--E--K------------------FIKA-------
-----------------AVGC-GIV-ES-ILN-WVK-FK-AQV-QLN-KKC-SAV-KHN-
RIK-GIP-KLD-DAND-AGGRNSTD--C-TL-ILT-EGD-SAK-TL-AVS-GL-GVV-GR
-DKY-GIF-PL-RGK-LLN-VR-EAS-HKQ-IME-NAE-INN-IIK-IVG-LQY-KKN-Y
ED-EDS-LKT-LRY-GKI-MI-MTD-QDQ-DGS-HIK-GL-LI-NFI-HH-NWP-SL-LR
H-RF-LEE-FI-TPIV-KVS-KNK-QEIAFYSI---PEF-EEWKNST-------PNYKKW
KVKYYKG------------------LGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAIS
LAF-SKKQVDDRKEWLTHFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNS
DNE

PF00521 // ENSGT00390000016222_1_Domain_6 (964, 1436)

RSIPSMVDGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTII
N--LAQNFVGSNNLNLLRPIGQFGTRLHGGKDSASPRYIFTMLSSLARLLFPPKDDHTLK
FLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWSCKIPNFDVREVVNNIRRLMDGEEPLP
MLPSYKNFKGTIEELAPNQYVISGEVAILNSTTIEISELPIRTWTQTYKEQVLEPMLNGT
EKTPPLITDYKEYHTD-TTVKFVVKMTEEKLAEAERVGLHKVFKLQTSLTCNSMVLFDHV
GCLKKYDTVLDILRDFYELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIE
NKPKKELIKVLIQRGY-----D---SDPVKAWKEAQQKVPDE--DENEESDTEKDTEKSD
SVTDSGPTFNYLLD-MPLWYLTKEKKDELCKLRNEKEQELDTLKKKTPADLWKED

ENSGT00390000016222_1_Linker_6_9 (1436, 1773)

LAVFI
EELEAVEAKEKQDEQVGLSGKG---------GKAKGKKT--QM-AEVLPSPHGKRVIPQV
TTEMKAEAEKKNKKKIKSENTEGRP-------QEDGIELESLKQRLEKK--LKRE---PG
TKTKKQTTLPFKPISKGKKKNPWSDSESDMSS-NESNFD---LPAREKKPRAVSTKAKFT
MDLDSDEDFSDFDKETNQD---EDYVLSD-A-----SPPKTKTSPKHTDR-ELKPQKS--
AM----SEKNLEA---------NDKDSVQLSSSPPAS---DFSAETEII-NPDSKKNVTV
KKTT-AKSQ-------------SSTSTTGAQK

PF08070 // ENSGT00390000016222_1_Domain_9 (1773, 1883)

RAAPKG-TK-----RNPALKSGVS-EKP
DLAKTK-NQRKRKPSTSDDSDSSFKKIISKAVTSKKPKGES-DDFHLD------FDSTVS
PRGKSRR-------AKKPIKYIEESDEDDLF-------

--------MEDLSPLQPVNENLQINKIKKNEDTKKRLSVERIYQKKT-QLEHILL-----
---------RP---DTYI--GSVEVVTQQMWVYDEEVGLNYRDVTFV

PF02518 // ENSGT00390000016222_1_Domain_0 (108, 253)

PGLYKIFDEILVN
AADNKQRDPKMNCIKVTIDSENNTISIWNNGKGIPVVEHKVEKVYVPALIFGQLLTSSNY
DDDEKKVTGGRNGYGAKLCNIFSTKFTVETACKEYKKMFKQ--TWMDNMGKAGEMTLKPF
SGEDYTCITFQP

ENSGT00390000016222_1_Linker_0_1 (253, 305)

DLSKFKMTSLDKDMVALMSRRAYDIAGSTKDVKVFLNGNRLP------
--VK

PF00204 // ENSGT00390000016222_1_Domain_1 (305, 590)

GFRSYVDLYVKDKLDETGNPLKIIHEEVNHRWEVCLTMSEKGFQQISFVNSIATS-
----------------------------------KGGRHVDYVADQIISRLIDVVKKKNK
GGVAVKAHQVKNHMWIFVNALIENPTFDSQTKENMTLQAKNFG-----------------
---------------SKCEL--------------------------SEKFI-----KA--
----------------AI-GC-GIV-ES-ILN-WVK-FK-AQV-QLN-KKC-SAV-KHN-
RIK-GIP-KLD-DAND-AGS-KNS-TDC-TL-ILT-EGD-SAK-TL-AVS-GL-GVV-GR
-DKY-GVF-PL-RGK-ILN-VR-EAS-HKQ-IME-NAE-INN-IIK-IVG-LQY-KKN-Y
ED-ADS-LKS-LRY-GKI-MI-MTD-QDQ-DGS-HIK-GL-LI-NFI-HH-NWP-SL-LK
H-CF-LEE-FIT-PIV-KVS-RNK-QEM-SF-YSL-PEF-EEW-KNT-T-----ENHKKW
KVKYYKG------------------LGTSTSKEAKEYFSDMSRHRIQFKYSGPEDDAAIS
LAF-SKKQIDDRKEWLTHFMEDRRQRKLLGLPEDYLYGKATKHLTYNDFINKELILFSNS
DNERSIPSMVDGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTII
N--LAQNFVGSNNLNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLARLLFPAKDDQTLK
FLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWSCKIPNFDVREVVNNIRRLMDGEEPLP
MLPSYKNFKGTIDELAPNQYVISGEVSIINSTTIEISELPVRTWTQVYKEQVLEPMLNGT
DKTPPLITDYREYHTD-TTVKFIVKMTEEKLAQAEHAGLHKVFKLQTNLTCNSMVLFDHV
GCLKKYDTALDILRDFFDLRLKYYGLRKEWLTGMLGAESAKLNNQARFILEKIEGKIVIE
NKPKKELIKVLIQRGY-----D---SDPVKAWKEAQQKSPGDNEEETEESDNEKETEKSD
SATDSGPTFNYLLD-MPLWYLTKEKKDELCRQRTEKEQELENLKRKSPSDLWKEDLAAFV
EELEVVEAKEKRDEQVGTIGKG------KAGGKPKAKKG--QV-AETLPSPHGRRVVPRV
TVEMKAEAEKKIRKKIKTENIEGSP-------QEDSLDPETLKQRLDKKLKTES-----G
PKQKKQSKLPFKPIKKENKRNPWSDSESDLSCDE-SEFYA--PPRETKSRRAVAANKKYT
VDLDSDTDISDSKEEFQDEE-DEDFIPSDGSSSKVKS------VPKATKGQTTSKVQEPP
KSSP--SHEGED---------LEPEDTKDMALASSSSSTLDFPVEL-EIPDPVPKKSTAV
K------K--------TAAKSQSSTSVTATKK

PF08070 // ENSGT00390000016222_1_Domain_9 (1773, 1883)

RAAPKTSKKT--SKTSLDS-VSETSEKT
VAAKSKKPRKRKP-SNSDDSDSDFGKGKSTAKAVKKSKMVD-DDFQIDS---NSSSTPVA
PRARPGR-------AKKPIKYLEESD----EDDMF---

---------MEVSPLQPVNENMQVNKIKKNEDAKKRLSIERIYQKKT-QLEHILL-----
---------RP-D-T-YI--GSVELVTQQMWVYDEDVGINYREVTFV

PF02518 // ENSGT00390000016222_1_Domain_0 (108, 255)

PGLYKIFDEILVN
AADNKQRDPKMSCIRVTIDPENNLISIWNNGKGIPVVEHKVEKMYVPALIFGQLLTSSNY
DDDEKKVTGGRNGYGAKLCNIFSTKFTVETASREYKKMFKQ--TWMDNMGRAGEMELKPF
SGEDYTCITFQPDLSKFKMQSLDKDIVALMVRRAYDIAGSTKDVKVFLNGNKLP------
--VKGFRSYVDMYLKDKLDETGNPLKVIHEQVNHRWEVCLTMSEKGFQQISFVNSIATS-
----------------------------------KGGRHVDYVADQIVTKLVDVVKKKNK
GGVAVKAHQVKNHMWIFVNALIENPTFDSQTKENMTL-------------------Q-P-
-K--S-F--G-S--T--C-Q--L-S--E--K------------------FIKA-------
-----------------AIGC-GIV-ES-ILN-WVK-FK-AQV-QLN-KKC-SAV-KHN-
RIK-GIP-KLD-DAND-AGGRNSTD--C-TL

PF01751 // ENSGT00390000016222_1_Domain_3 (632, 769)

-ILT-EGD-SAK-TL-AVS-GL-GVV-GR
-DKY-GVF-PL-RGK-MLN-VR-EAS-HKQ-IME-NAE-INN-IIK-IVG-LQY-KKN-Y
ED-EDS-LKT-LRY-GKI-MI-MTD-QDQ-DGS-HIK-GL-LI-NFI-HH-NWP-SL-LR
H-RF-LEE-FI-TPIV-KVS-KNK-QEMAFYSL---PEF-EEWKSST-------PNYKKW
KVKYYKG------------------LGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAIS
LAF-SKKQIDDRKEWLTNFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNS
DNE

PF00521 // ENSGT00390000016222_1_Domain_6 (964, 1436)

RSIPSMVDGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTII
N--LAQNFVGSNNLNLLQPIGQFGTRLHGGKDSASPRYIFTMLSSLARLLFPPKDDHTLK
FLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWSCKIPNFDVREVVNNIRRLMDGEEPLP
MLPSYKNFKGTIEELAPNQYVISGEVAILNSTTIEISELPIRTWTQTYKEQVLEPMLNGT
EKTPPLITDYREYHTD-TTVKFVVKMTEEKLAEAERVGLHKVFKLQTSLTCNSMVLFDHV
GCLKKYDTVLDILRDFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIE
NKPKKELIKVLIQRGY-----D---SDPVKAWKEAQQKVPDE--EENEESDNEKETEKSD
SVTDSGPTFNYLLD-MPLWYLTKEKKDELCRLRNEKEQELDTLKRKSPSDLWKED

ENSGT00390000016222_1_Linker_6_9 (1436, 1773)

LATFI
EELEAVEAKEKQDEQVGLPGKG---------GKAKGKKT--QM-AEVLPSPRGQRVIPRI
TIEMKAEAEKKNKKKIKNENTEGSP-------QEDGMELEGLKQRLEKK--QKRE---PG
TKTKKQTTLPFKPIKKGKKRNPWSDSESDRSS-DESNFD---VPPRETEPRRAATKTKFT
VDLDSDEDFSDFDEK-TDD---EDFVPSD-A-----SPPKTKTSPKLTNR-DLKPQK---
RAMSDLEAD--D---------AK--DSVPLSSSPPAT---HFPNETEIT-NTVPKKNVTV
KKTA-AKSQ-------------SSTSTTGAKK

PF08070 // ENSGT00390000016222_1_Domain_9 (1773, 1882)

RAAPKG-TK-----KEPALNSGIS-QKP
DPAKTK-IRRKRKPSTSDDSDSNFEKIVSKAVTSKKSRGES-DDFHMD------FDSAVA
PRAKSVR-------AKKPIKYLEESDEDDLF-------

---------MEVSPLQPVNENMQVNKIKKNEDAKKRPSIERIYQKKT-QLEHILL-----
---------RP-D-T-YI--GSVELVTQQMWVYDEDVGINYREVTFV

PF02518 // ENSGT00390000016222_1_Domain_0 (108, 253)

PGLYKIFDEILVN
AADNKQRDPKMSCIRVTIDPENNLISIWNNGKGIPVVEHKVEKMYVPALIFGQLLTSSNY
DDDEKKVTGGRNGYGAKLCNIFSTKFTVETASREYKKMFKQ--TWMDNMGRAGEMELKPF
SGEDYTCITFQP

ENSGT00390000016222_1_Linker_0_1 (253, 305)

DLSKFKMQSLDKDIVALMVRRAYDIAGSTKDVKVFLNGNKLP------
--VK

PF00204 // ENSGT00390000016222_1_Domain_1 (305, 590)

GFRSYVDMYLKDKLDETGNPLKVIHEQVNHRWEVCLTMSEKGFQQISFVNSIATS-
----------------------------------KGGRHVDYVADQIVTKLVDVVKKKNK
GGVAVKAHQVKNHMWIFVNALIENPTFDSQTKENMTL-------------------Q-P-
-K--S-F--G-S--T--C-Q--L-S--E--K------------------FIKA-------
-----------------AIGC-GIV-ES-ILN-WVK-FK-AQV-QLN-KKC-SAV-KHN-
RIK-GIP-KLD-DAND-AGGRNSAD--C-TL-ILT-EGD-SAK-TL-AVS-GL-GVV-GR
-DKY-GVF-PL-RGK-MLN-VR-EAS-HKQ-IME-NAE-INN-IIK-IVG-LQY-KKN-Y
ED-EDS-LKT-LRY-GKI-MI-MTD-QDQ-DGS-HIK-GL-LI-NFI-HH-NWP-SL-LR
H-RF-LEE-FI-TPIV-KVS-KNK-QEMSFYSL---PEF-EEWKSST-------PNHKKW
KVKYYKG------------------LGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAIS
LAF-SKKQIDDRKEWLTNFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNS
DNERSIPSMVDGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTII
N--LAQNFVGSNNLNLLQPIGQFGTRLHGGKDSASPRYIFTMLSSLARLLFPPKDDHTLK
FLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWSCKIPNFDVREVVNNIRRLMDGEEPLP
MLPSYKNFKGTIEELAPNQYVISGEVAILNSTTIEISELPIRTWTQTYKEQVLEPMLNGT
EKTPPLITDYREYHTD-TTVKFVVKMTEEKLAEAERVGLHKVFKLQTSLTCNSMVLFDHV
GCLKKYDTVLDILRDFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIE
NKPKKELIKVLIQRGY-----D---SDPVKAWKEAQQKVPDE--EENEESDNEKETEKSD
SVTDSGPTFNYLLD-MPLWYLTKEKKDELCRLRNEKEQELDTLKRKSPSDLWKEDLATFI
EELEAVEAKEKQDEQVGPPGKG---------GKAKGKKT--QM-AEVLPSPRGQRVIPRI
TIEMKAEAEKKNKKKIKNENTEGSP-------QEDGMELEGLKQRLEKK--QKRE---PG
TKTKKQTTLSFKPIKKGKKRNPWSDSESDRSS-DESNFD---VPPRETEPRRAATKTKFT
VDLDSDEDFSDFDEK-TDD---EDFVPSD-A-----SPPKTKTSPKLTNK-DLKPQK---
SAMSDIEAD--D---------AK--DSVPLSSSPPAA---HFPNETEIT-NPVPKKNVTV
KKTA-AKSQ-------------SSTSTTGAKK

PF08070 // ENSGT00390000016222_1_Domain_9 (1773, 1883)

RAAPKG-TK-----KEPALNSGIS-QKP
DPAKTK-IRRKRKPSTSDDSDSNFEKIVSKAVTSKKSRGES-DDFHMD------FDSAVA
PRAKSVR-------AKKPIKYLEESDEDDLF-------

---------MEVSPLQPVNENMQVNKIKKNEDAKKRLSVERIYQKKT-QLEHILL-----
---------RP-D-T-YI--GSVELVTQQMWVYDEDVGINYREVTFV

PF02518 // ENSGT00390000016222_1_Domain_0 (108, 255)

PGLYKIFDEILVN
AADNKQRDPKMSCIRVTIDPENNLISIWNNGKGIPVVEHKVEKMYVPALIFGQLLTSSNY
DDDEKKVTGGRNGYGAKLCNIFSTKFTVETASREYKKMFKQ--TWMDNMGRAGEMELKPF
NGEDYTCITFQPDLSKFKMQSLDKDIVALMVRRAYDIAGSTKDVKVFLNGNKLP------
--VKGFRSYVDMYLKDKLDETGNSLKVIHEQVNHRWEVCLTMSEKGFQQISFVNSIATS-
----------------------------------KGGRHVDYVADQIVTKLVDVVKKKNK
GGVAVKAHQVKNHMWIFVNALIENPTFDSQTKENMTL-------------------Q-P-
-K--S-F--G-S--T--C-Q--L-S--E--K------------------FIKA-------
-----------------AIGC-GIV-ES-ILN-WVK-FK-AQV-QLN-KKC-SAV-KHN-
RIK-GIP-KLD-DAND-AGGRNSTE--C-TL

PF01751 // ENSGT00390000016222_1_Domain_3 (632, 769)

-ILT-EGD-SAK-TL-AVS-GL-GVV-GR
-DKY-GVF-PL-RGK-ILN-VR-EAS-HKQ-IME-NAE-INN-IIK-IVG-LQY-KKN-Y
ED-EDS-LKT-LRY-GKI-MI-MTD-QDQ-DGS-HIK-GL-LI-NFI-HH-NWP-SL-LR
H-RF-LEE-FI-TPIV-KVS-KNK-QEMAFYSL---PEF-EEWKSST-------PNHKKW
KVKYYKG------------------LGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAIS
LAF-SKKQIDDRKEWLTNFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNS
DNE

PF00521 // ENSGT00390000016222_1_Domain_6 (964, 1436)

RSIPSMVDGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTII
N--LAQNFVGSNNLNLLQPIGQFGTRLHGGKDSASPRYIFTMLSSLARLLFPPKDDHTLK
FLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWSCKIPNFDVREIVNNIRRLMDGEEPLP
MLPSYKNFKGTIEELAPNQYVISGEVAILNSTTIEISELPIRTWTQTYKEQVLEPMLNGT
EKTPPLITDYREYHTD-TTVKFVVKMTEEKLAEAERVGLHKVFKLQTSLTCNSMVLFDHV
GCLKKYDTVLDILRDFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIE
NKPKKELIKVLIQRGY-----D---SDPVKAWKEAQQKVPDE--EENEESDNEKETEKSD
SVTDSGPTFNYLLD-MPLWYLTKEKKDELCRLRNEKEQELDTLKRKSPSDLWKED

ENSGT00390000016222_1_Linker_6_9 (1436, 1773)

LATFI
EELEAVEAKEKQDEQVGLPGKG---------GKAKGKKT--QM-AEVLPSPRGQRVIPRI
TIEMKAEAEKKNKKKIKNENTEGSP-------QEDGVELEGLKQRLEKK--QKRE---PG
TKTKKQTTLPFKPIKKGKKRNPWSDSESDRSS-DESNFD---VPPRETEPRRAATKTKFT
MDLDSDEDFSDFDEK-TDD---EDFVPSD-A-----SPPKTKTSPKLSNK-ELKPQK---
SVVSDLEAN--D---------AK--DSVPLSSSPPAT---HFPDETEIT-NPVPKKNVTV
KKTA-AKSQ-------------SSTSTTGAKK

PF08070 // ENSGT00390000016222_1_Domain_9 (1773, 1882)

RAAPKG-TK-----RDPALNSGVS-QKP
DPAKTK-NRRKRKPSTSDDSDSNFEKIVSKAVTSKKSKGES-DDFHMD------FDSAVA
PRAKSVR-------AKKPIKYLEESDEDDLF-------

------------MELLPVNENMQMNK-KKNEDAKKRLSIERIYQKKT-QLEHILL-----
---------RP-D-T-YI--GSVELVTQQMWVYDEDVGINYREVTFV

PF02518 // ENSGT00390000016222_1_Domain_0 (108, 255)

PGLYKIFDEILVN
AADNKQRDPKMSCIRVTIDPENNLISIWNNGKGIPVVEHKVEKMYVPALIFGQLLTSSNY
DDDEKKVTGGRNGYGAKLCNIFSTKFTVETASKEYKKMFKQ--TWMDNMGRAGDMELKPF
NGEDYTCITFQPDLSKFKMQSLDKDIVALMVRRAYDIAGSTKDVKVFLNGNKLP------
--VKGFRSYVDMYLKDKVDETGNALKVVHEQVNPRWEVCLTMSEKGFQQISFVNSIATS-
----------------------------------KGGRHVDYVADQIVSKLVDVVKKKNK
GGVAVKAHQVKNHMWIFVNCLIENPTFDSQTKENMTL-------------------Q-A-
-K--S-F--G-S--T--C-Q--L-S--E--K------------------FIKA-------
-----------------AIGC-GIV-ES-ILN-WVK-FK-AQI-QLN-KKC-SAV-KHN-
RIK-GIP-KLD-DAND-AGSRNSTE--C-TL

PF01751 // ENSGT00390000016222_1_Domain_3 (632, 769)

-ILT-EGD-SAK-TL-AVS-GL-GVV-GR
-DKY-GVF-PL-RGK-ILN-VR-EAS-HKQ-IME-NAE-INN-IIK-IVG-LQY-KKN-Y
ED-EDS-LKT-LRY-GKI-MI-MTD-QDQ-DGS-HIK-GL-LI-NFI-HH-NWP-SL-LR
H-RF-LEE-FI-TPIV-KVS-KNK-QELAFYSL---PEF-EEWKSST-------PNHKKW
KVKYYKG------------------LGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAIS
LAF-SKKQVDDRKEWLTHFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNS
DNE

PF00521 // ENSGT00390000016222_1_Domain_6 (964, 1436)

RSIPSMVDGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTII
N--LAQNFVGSNNLNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLTRLLFPPKDDHTLK
FLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWSCKIPNFDVREVVNNIRRLLDGEEPLP
MLPSYKNFKGTIEELASNQYVISGEVAILNSTTIEISELPIRTWTQTYKEQVLEPMLNGT
EKTPPLITDYREYHTD-TTVKFVIKMTEEKLAEAERVGLHKVFKLQTSLTCNSMVLFDHV
GCLKKYDTVVDILKDFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIE
NKPKKELIKVLIQRGY-----D---SDPVKAWKEAQQKVPDE--EENEES----DNENSD
STADSGPTFNYLLD-MPLWYLTKEKKDELCKQRDEKEQELNTLKKKSPSDLWKED

ENSGT00390000016222_1_Linker_6_9 (1436, 1773)

LAVFI
EELEVVENKEKQDEQVGLPGKG---------GKAKGKKA--QT-SEVLPSPGGKRVIPQV
TMEMKAEAEKKIRKKIKSENVEGTP-------TEDGQELGGLKQRLEKKQRQKRE---PG
TMAKKQTTLPFKPIRKGKKRNPWSDSESDMSS-NESHFD---VPPREKEPRRATTKAKFT
EDLDSDEDFSGFDEKD-ED---EDFFPLD-T-----SPPKTKIPPKNTKK-ALKPQKSTM
S-V------DLE---------GDVKDSVPASPGPAA--AADFPAETEQL-KPSSKQTAAV
KKTVAKSQS-------------STSTAAGTKK

PF08070 // ENSGT00390000016222_1_Domain_9 (1773, 1882)

RAAPKG-TK-----SDSTLSAHGP-EKP
DPAKAK-SSRKRKQSSSDDSDSDFEKLTSKASVSKKSKGEN-QDFHVD------LDETVA
PRAKSGR-------ARKPIKYLEESDEDD----LF---

---------MEVSPLQPVNENMQVNKIKKNEDAKKRLSIERIYQKKT-QLEHILL-----
---------RP-D-T-YI--GSVELVTQQMWVYDEDVGINYREVTFV

PF02518 // ENSGT00390000016222_1_Domain_0 (108, 255)

PGLYKIFDEILVN
AADNKQRDPKMSCIRVTIDPENNLISIWNNGKGIPVVEHKVEKMYVPALIFGQLLTSSNY
DDDEKKVTGGRNGYGAKLCNIFSTKFTVETASREYKKMFKQ--TWMDNMGRAGEMELKPF
SGEDYTCITFQPDLSKFKMQSLDKDIVALMVRRAYDIAGSTKDVKVFLNGNKLP------
--VKGFRSYVDMYLKDKLDETGNPLKVIHEQVNHRWEVCLTMSEKGFQQISFVNSIATS-
----------------------------------KGGRHVDYVADQIVTKLVDVVKKKNK
GGVAVKAHQVKNHMWIFVNALIENPTFDSQTKENMTL-------------------Q-P-
-K--S-F--G-S--T--C-Q--L-S--E--K------------------FIKA-------
-----------------AIGC-GIV-ES-ILN-WVK-FK-AQV-QLN-KKC-SAV-KHN-
RIK-GIP-KLD-DAND-AGGRNSTD--C-TL

PF01751 // ENSGT00390000016222_1_Domain_3 (632, 769)

-ILT-EGD-SAK-TL-AVS-GL-GVV-GR
-DKY-GVF-PL-RGK-MLN-VR-EAS-HKQ-IME-NAE-INN-IIK-IVG-LQY-KKN-Y
ED-EDS-LKT-LRY-GKI-MI-MTD-QDQ-DGS-HIK-GL-LI-NFI-

ENSGT00390000016222_1_Linker_3_5 (769, 790)

HH-NWP-SL-LR
H-RF-LEE-

PF16898 // ENSGT00390000016222_1_Domain_5 (790, 962)

FI-TPIV-KVS-KNK-QEMAFYSL---PEF-EEWKSST-------PNYKKW
KVKYYKG------------------LGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAIS
LAF-SKKQIDDRKEWLTNFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNS
DNERSIPSMVDGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTII
N--LAQNFVGSNNLNLLQPIGQFGTRLHGGKDSASPRYIFTMLSSLARLLFPPKDDHTLK
FLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWSCKIPNFDVREVVNNIRRLMDGEEPLP
MLPSYKNFKGTIEELAPNQYVISGEVAILNSTTIEISELPIRTWTQTYKEQVLEPMLNGT
EKTPPLITDYREYHTD-TTVKFVVKMTEEKLAEAERVGLHKVFKLQTSLTCNSMVLFDHV
GCLKKYDTVLDILRDFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIE
NKPKKELIKVLIQRGY-----D---SDPVKAWKEAQQKVPDE--EENEESDNEKETEKSD
SVTDSGPTFNYLLD-MPLWYLTKEKKDELCRLRNEKEQELDTLKRKSPSDLWKEDLATFI
EELEAVEAKEKQDEQVGLPGKG---------GKAKGKKT--QM-AEVLPSPRGQRVIPRI
TIEMKAEAEKKNKKKIKNENTEGSP-------QEDGMELEGLKQRLEKK--QKRE---PG
TKTKKQTTLPFKPIKKGKKRNPWSDSESDRSS-DESNFD---VPPRETEPRRAATKTKFT
VDLDSDEDFSDFDEK-TDD---EDFVPSD-A-----SPPKTKTSPKLTNR-DLKPQK---
RAMSDLEAD--D---------AK--DSVPLSSSPPAT---HFPNETEIT-NTVPKKNVTV
KKTA-AKSQ-------------SSTSTTGAKK

PF08070 // ENSGT00390000016222_1_Domain_9 (1773, 1882)

RAAPKG-TK-----KEPALNSGIS-QKP
DPAKTK-IRRKRKPSTSDDSDSNFEKIVSKAVTSKKSRGES-DDFHMD------FDSAVA
PRAKSVR-------AKKPIKYLEESDEDDLF-------

---------MELSPLQPVNENMQMNK-KKNEDAKKRLSIERIYQKKT-QLEHILL-----
---------RP-D-T-YI--GSVELVTQQMWVYDEDVGINYREVTFV

PF02518 // ENSGT00390000016222_1_Domain_0 (108, 255)

PGLYKIFDEILVN
AADNKQRDPKMSCIRVTIDPENNLISIWNNGKGIPVVEHKVEKMYVPALIFGQLLTSSNY
DDDEKKVTGGRNGYGAKLCNIFSTRFTVETASKEYKKMFKQ--TWMDNMGRAGDMELKPF
NGEDYTCITFQPDLSKFKMQSLDKDIVALMVRRAYDIAGSTKDVKVFLNGNKLP------
--VKGFRSYVDMYLKDKLDETGNALKVVHEQVNPRWEVCLTMSEKGFQQISFVNSIATS-
----------------------------------KGGRHVDYVADQIVSKLVDVVKKKNK
GGVAVKAHQVKNHMWIFVNALIENPTFDSQTKENMTL-------------------Q-A-
-K--S-F--G-S--T--C-Q--L-S--E--K------------------FIKA-------
-----------------AIGC-GIV-ES-ILN-WVK-FK-AQI-QLN-KKC-SAV-KHN-
RIK-GIP-KLD-DAND-AGSRNSTE--C-TL

PF01751 // ENSGT00390000016222_1_Domain_3 (632, 769)

-ILT-EGD-SAK-TL-AVS-GL-GVV-GR
-DKY-GVF-PL-RGK-ILN-VR-EAS-HKQ-IME-NAE-INN-IIK-IVG-LQY-KKN-Y
ED-EDS-LKT-LRY-GKI-MI-MTD-QDQ-DGS-HIK-GL-LI-NFI-HH-NWP-SL-LR
H-RF-LEE-FI-TPIV-KVS-KNK-QELAFYSL---PEF-EEWKSST-------PNHKKW
KVKYYKG------------------LGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAIS
LAF-SKKQVDDRKEWLTHFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNS
DNE

PF00521 // ENSGT00390000016222_1_Domain_6 (964, 1436)

RSIPSMVDGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTII
N--LAQNFVGSNNLNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLTRLLFPPKDDHTLK
FLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWSCKIPNFDIREVVNNIRRLLDGEEPLP
MLPSYKNFKGTIEELASNQYVINGEVAILNSTTIEISELPIRTWTQTYKEQVLEPMLNGT
EKTPPLITDYREYHTD-TTVKFVIKMTEEKLAEAERVGLHKVFKLQTSLTCNSMVLFDHV
GCLKKYDTVLDILKDFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIE
NKPKKELIKVLIQRGY-----D---SDPVKAWKEAQQKVPDE--EENEES----DNENSD
SVAESGPTFNYLLD-MPLWYLTKEKKDELCKQRNEKEQELNTLKNKSPSDLWKED

ENSGT00390000016222_1_Linker_6_9 (1436, 1772)

LAVFI
EELEVVEAKEKQDEQVGLPGKG---------GKAKGKKA--QM-SEVLPSPHGKRVIPQV
TMEMKAEAEKKIRKKIKSENVEGTP-------TENGLELGSLKQRIEKK--QKKE---PG
AMTKKQTTLAFKPIKKGKKRNPWSDSESDMSS-NESNVD---VPPREKDPRRAATKAKFT
MDLDSDEDFSGSDGKD-ED---EDFFPLD-T-----TPPKTKIPQKNTKK-ALKPQKSAM
S-G------DPE---------SDEKDSVPASPGPPA---ADLPADTEQL-KPSSKQTVAV
KKTATKSQS-------------STS-TAGTK

PF08070 // ENSGT00390000016222_1_Domain_9 (1772, 1882)

KRAVPKG-SK-----SDSALNAHGP-EKP
VPAKAK-NSRKRKQSSSDDSDSDFEKVVSKVAASKKSKGEN-QDFRVD------LDETMV
PRAKSGR-------AKKPIKYLEESDDDD----LF---

---------MELSPLQPVNENMQVNKIKKNEDAKKRLSIERIYQKKT-QLEHILL-----
---------RP---DTYI--GSVELVTQQMWVYDEDIGINYREVTFV

PF02518 // ENSGT00390000016222_1_Domain_0 (108, 255)

PGLYKIFDEILVN
AADNKQRDPKMSCIRVTIDPENNLISIWNNGRGIPVVEHKVEKVYVPALIFGQLLTSSNY
DDEEKKVTGGRNGYGAKLCNIFSTKFTVETASKEYKKMFKQ--TWMDNMGRAGEMELKPF
SGEDYTCITFQPDLSKFKMQSLDKDIVALMVRRAYDIAGSTKDVKVFLNGNKLP------
--VKGFRSYVDMYLKDKLDETGNPLKVIHEQVNHRWEVCLTMSEKGFQQISFVNSIATS-
----------------------------------KGGRHVDYVADQIVTKLVDVVKKKNK
GGVAVKAHQVKNHMWIFVNALIENPTFDSQTKENMTLQVKS-------------------
------F--G-----STCQL--------------------------SEKFIKA-------
-----------------AVGC-GIV-ES-ILN-WVK-FK-AQV-QLN-KKC-SAV-KHN-
RIK-GIP-KLD-DAND-AGSRNSTE--C-TL

PF01751 // ENSGT00390000016222_1_Domain_3 (632, 769)

-ILT-EGD-SAK-TL-AVS-GL-GVV-GR
-DKY-GVF-PL-RGK-ILN-VR-EAS-HKQ-IME-NAE-INN-IIK-IVG-LQY-KKN-Y
ED-EDS-LKT-LRY-GKI-MI-MTD-QDQ-DGS-HIK-GL-LI-NFI-

ENSGT00390000016222_1_Linker_3_5 (769, 790)

HH-NWP-SL-LR
H-CF-LEE-

PF16898 // ENSGT00390000016222_1_Domain_5 (790, 1030)

FI-TPIV-KVS-KNK-QELAFYSL---PEF-EEWKSST-------PNHKKW
KVKYYKG------------------LGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAIS
LAF-SKKQIDDRKEWLTHFMEDRRQRKLLGLPEVKMLNVSCKMC---YFINIGF------
------------------------------------------------------------
-----ILYEVCNNLNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLARLLFPPKDDHTLR
FLYDDNQRVEPEWYIPIIPMVLVNGAEGIGTGWSCKIPNFDVREVVNNIRRLMDGEEPLP
MLPSYKNFKGTIEELAPNQYVINGEVAILNSTTIEISELPIRTWTQTYKEQVLEPMLNGT
EKTPPLITDYREYHTD-TTVRFVVKMTEEKLAEAERAGLHKVFKLQTSLTCNSMVLFDHV
GCLKKYDTVLDILRDFFELRLKYYGLRKEWLLGMLGAESSKLNNQARFILEKIDGKIIIE
NKPKKELIKVLIQRGY-----D---SDPVKAWKEAQQKVPDE--EENEESDSEKEAAKGD
SATDTGPTFNYLLD-MPLWYLTKEKKDELCRQRNEKEQELDTLKKKSPSDLWKEDLAAFI
EELEAVEAKEKQDEQVGLPGKG---------GKAKGKKT--HM-AEVMPSQQGVRVIPRV
TTEMKAEAEKKIKKKIKSENTEGTP-------VEDSVELESLKQRLEKK--QKRE-----
--AKKQTTLPFKPIKKGKRRNPWSDSESDVSS-AESNFD---VPTREVEPRRTAAKTKFT
MDLDSDEDFSDSDEKTED----DDFVPSD-A-----GPPQAKTLPKLTKK-EPKPQKS-T
VSVTG-----PEA--------EDAEDREPDSSGPSA----EFPAKSEVT-KPPPEGSVPV
KKTAGKGR--------------SAASTADTKKR

PF08070 // ENSGT00390000016222_1_Domain_9 (1774, 1882)

AAPRG-AK-----KDPALQPEAS-QKP
EPAKTK-NRRKRKPSTSDDSDSNFEKIISKGAISKKPKGES-DDFHLD------LHAAVA
PRAKSGR-------AKKPIKYLEESDEDDLF-------

---------MELSPLQPVNENMQMNK-KKNEDAKKRLSIERIYQKKT-QLEHILL-----
---------RP-D-T-YI--GSVELVTQQMWVYDEDVGINYREVTFV

PF02518 // ENSGT00390000016222_1_Domain_0 (108, 255)

PGLYKIFDEILVN
AADNKQRDPKMSCIRVTIDPENNLISIWNNGKGIPVVEHKVEKMYVPALIFGQLLTSSNY
DDDEKKVTGGRNGYGAKLCNIFSTRFTVETASKEYKKMFKQ--TWMDNMGRAGDMELKPF
NGEDYTCITFQPDLSKFKMQSLDKDIVALMVRRAYDIAGSTKDVKVFLNGNKLP------
--VKGFRSYVDMYLKDKLDETGNALKVVHEQVNPRWEVCLTMSEKGFQQISFVNSIATS-
----------------------------------KGGRHVDYVADQIVSKLVDVVKKKNK
GGVAVKAHQVKNHMWIFVNALIENPTFDSQTKENMTL-------------------Q-A-
-K--S-F--G-S--T--C-Q--L-S--E--K------------------FIKA-------
-----------------AIGC-GIV-ES-ILN-WVK-FK-AQI-QLN-KKC-SAV-KHN-
RIK-GIP-KLD-DAND-AGSRNSTE--C-TL

PF01751 // ENSGT00390000016222_1_Domain_3 (632, 769)

-ILT-EGD-SAK-TL-AVS-GL-GVV-GR
-DKY-GVF-PL-RGK-ILN-VR-EAS-HKQ-IME-NAE-INN-IIK-IVG-LQY-KKN-Y
ED-EDS-LKT-LRY-GKI-MI-MTD-QDQ-DGS-HIK-GL-LI-NFI-HH-NWP-SL-LR
H-RF-LEE-FI-TPIV-KVS-KNK-QELAFYSL---PEF-EEWKSST-------PNHKKW
KVKYYKG------------------LGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAIS
LAF-SKKQVDDRKEWLTHFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNS
DNE

PF00521 // ENSGT00390000016222_1_Domain_6 (964, 1436)

RSIPSMVDGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTII
N--LAQNFVGSNNLNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLTRLLFPPKDDHTLK
FLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWSCKIPNFDIREVVNNIRRLLDGEEPLP
MLPSYKNFKGTIEELASNQYVINGEVAILNSTTIEISELPIRTWTQTYKEQVLEPMLNGT
EKTPPLITDYREYHTD-TTVKFVIKMTEEKLAEAERVGLHKVFKLQTSLTCNSMVLFDHV
GCLKKYDTVLDILKDFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIE
NKPKKELIKVLIQRGY-----D---SDPVKAWKEAQQKVPDE--EENEES----DNENSD
SVAESGPTFNYLLD-MPLWYLTKEKKDELCKQRNEKEQELNTLKNKSPSDLWKED

ENSGT00390000016222_1_Linker_6_9 (1436, 1772)

LAVFI
EELEVVEAKEKQDEQVGLPGKG---------GKAKGKKA--QM-SEVLPSPHGKRVIPQV
TMEMKAEAEKKIRKKIKSENVEGTP-------TENGLELGSLKQRIEKK--QKKE---PG
AMTKKQTTLAFKPIKKGKKRNPWSDSESDMSS-NESNVD---VPPREKDPRRAATKAKFT
MDLDSDEDFSGSDGKD-ED---EDFFPLD-T-----TPPKTKIPQKNTKK-ALKPQKSAM
S-G------DPE---------SDEKDSVPASPGPPA---ADLPADTEQL-KPSSKQTVAV
KKTATKSQS-------------STS-TAGTK

PF08070 // ENSGT00390000016222_1_Domain_9 (1772, 1882)

KRAVPKG-SK-----SDSALNAHGP-EKP
VPAKAK-NSRKRKQSSSDDSDSDFEKVVSKVAASKKSKGEN-QDFRVD------LDETMV
PRAKSGR-------AKKPIKYLEESDDDD----LF---

---------MEVSPLQPVNENMQINKIKKNEDAKKRLSIERIYQKKT-QLEHILL-----
---------RP-D-T-YI--GSVELVTQQMWVYDEDIGINYREV

PF02518 // ENSGT00390000016222_1_Domain_0 (105, 255)

TFVPGLYKIFDEILVN
AADNKQRDPKMSCIRVTIDPENNLISIWNNGKGIPVVEHKVEKMYVPALIFGQLLTSSNY
DDDEKKVTGGRNGYGAKLCNIFSTKFTVETASREYKKKFKQ--TWMDNMGKAGEMELKPF
SGEDYTCITFQPDL

ENSGT00390000016222_1_Linker_0_1 (255, 309)

SKFKMQSLDKDIVALMVRRAYDIAGSTKDVKVFLNGNTLP------
--VKGFRS

PF00204 // ENSGT00390000016222_1_Domain_1 (309, 595)

YVDMYLKDKVDETGNPLKVIYEQVNHRWEVCLTMSEKGFQQISFVNSIATS-
----------------------------------KGGRHVDYVADQIVTKLVDVVKKKNK
GGVAVKAHQVKNHMWIFVNALIENPTFDSQTKENMTL-------------------Q-V-
-K--S-F--G-S--T--C-Q--L-S--E--K------------------FIKA-------
-----------------ATGC-GIV-ES-ILN-WVK-FK-AQI-QLN-KKC-SAV-KHN-
RIK-GIP-KLD-DAND-AGGRNSTD--C-TL-ILT-EGD-SAK-TL-AVS-GL-GVV-GR
-DKY-GVF-PL-RGK-ILN-VR-EAS-HKQ-IME-NAE-INN-IIK-IVG-LQY-KKS-Y
DD-EDS-LKT-LRY-GKI-MI-MTD-QDQ-DGS-HIK-GL-LI-NFI-HH-NWP-SL-LR
H-RF-LEE-FI-TPIV-KVS-KNK-QEIAFYSL---PEF-EEWKSST-------PNHKKW
KVKYYKG------------------LGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAIS
LAF-SKKQIDDRKEWLTHFMEDRRQRKLLGLPEDYLYGQATTYLTYNDFINKELILFSNS
DNERSIPSMVDGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTII
N--LAQNFVGSNNLNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLARLLFPPKDDHTLK
FLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWSCKIPNFDVREVVNNIRRLMDGEEPLP
MLPSYKNFKGTIEELASNQYVISGEVAILNSTTIEISELPIRTWTQTYKEQVLEPMLNGT
EKTPPLITDYREYHTD-TTVKFVVKMTEEKLAEAERAGLHKVFKLHTSLTCNSMVLFDHV
GCLKKYDTVLDILRDFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIE
NKPKKELIKVLIQRGY-----D---SDPVKAWKEAQQKVPEE--EENEDSDNEKETEKSD
SVTDSGPTFNYLLD-MPLWYLTKEKKDELCKLRNEKEQELETLKKKSPSDLWKEDLAAFI
EELETVEAKEKQDEQVGFPGKG---------GKGKGKKA--QM-AEVLPSPSGKRVIPRV
TVEMKAEAEKKIKRKIKSENTEGSP-------QEDSVEPESLKQRLEKK--QKRE---PG
TKTKKQTTLPFKPVKKGKKKNPWSDSDSDISD-NESNFD---LPPRETEPRRAAAKSKFI
IDLDSEEDFSDFDEK-TQD---EDFVPSD-P-----SPPKAKTSPKHTNK-ELRPQK---
SAKSAFEAVDLDA--------DDAKDNVPLPSSSPTA---DLPAETEIT-NPISKKGATV
KKTA-AKSQ-------------SSNSTAGTKK

PF08070 // ENSGT00390000016222_1_Domain_9 (1773, 1883)

RAAPKG-TK-----KDSGLNSDLSPKKP
GPAKSK-NPRKRKPSTSDDSDSNFEKMISKAVTSKKSKGES-NDFQMD------LDSAVA
PRAKSVR-------AKKPIRYLEESDEDDLF-------

---------MELSPLQPVNENMLMNK-KKNEDGKKRLSIERIYQKKT-QLEHILL-----
---------RP-D-T-YI--GSVELVTQQMWVYDEDVGINYREVTFVPGLYKIFDEILVN
AADNKQRDPKMSCIRVTIDPAERLE-----------------------------------
-----SKMSGRNGYGAKLCNIFSTKFTVETASREYKKMFKQ--TWMDNMGRAGDMELKPF
SGEDYTCITFQPDLSKFKMQSLDKDIVALMVRRAYDIAGSTKDVKVFLNGNRLP------
--VK

PF00204 // ENSGT00390000016222_1_Domain_1 (305, 590)

GFRSYVDLYLKDKVDETGNSLKVVHEQVNPRWEVCLTMSEKGFQQISFVNSIATS-
----------------------------------KGGRHVDYIADQIVGKLVDVVKKKNK
GGVAVKAHQVKNHMWIFVNALIENPTFDSQTKENMTL-------------------Q-A-
-K--S-F--G-S--T--C-Q--L-S--E--K------------------FIKA-------
-----------------AIGC-GIV-ES-ILN-WVK-FK-AQI-QLN-K

ENSGT00390000016222_1_Linker_1_3 (590, 632)

KC-SAV-KHN-
KIK-GIP-KLD-DAND-AGSRNSTD--C-TL

PF01751 // ENSGT00390000016222_1_Domain_3 (632, 769)

-ILT-EGD-SAK-TL-AVS-GL-GVV-GR
-DKY-GVF-PL-RGK-MLN-VR-EAS-HKQ-IME-NAE-INN-IIK-IVG-LQY-KKN-Y
ED-EDS-LKT-LRY-GKI-MI-MTD-QDQ-DGS-HIK-GL-LI-NFI-HH-NWP-SL-LR
H-RF-LEE-FI-TPIV-KVS-KNK-QEIAFYSL---PEF-EEWKSST-------PNHKKW
KVKYYKG------------------LGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAIS
LAF-SKKQVEDRKEWLTNFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNS
DNERSIPSMVDGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTII
N--LAQNFVGSNNLNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLARLLFPPKDDHTLR
FLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWSCKIPNFDVREVVNNIRRLLDGEEPLP
MLPSYKNFKGTIEELASNQYVINGEVAILDSTTIEISELPIRMWTQTYKEQVLEPMLNGT
EKTPPLITDYREYHTD-TTVKFVIKMTEGKLAEAERVGLHKVFKLQTSLTCNSMVLFDHV
GCLKKYDTVLDILRDFFELRLKYYGLRKEWLLGMLGAESSKLNNQARFILEKIDGKIVIE
NKPKKELIKVLIERGY-----D---SDPVKAWREAQQKVPDE--EENEESDT--ETSTSN
SAAESGPTFNYLLD-MPLWYLTKEKKDELCKQRNEKEQELNTLKKKSPSDLWKEDLAVFI
EELEVVEAKEKQDEQAGLPGKV---------GKTKGKKA--QMASEVLPSPRGKRVIPQV
TVEMKAEAEKKIRKKIKSENIEGTP-------AEDGVETGSLRQRVEKK--QKRE---P-
------------------------------------------------------AKAKFT
VDLDSDKDFSDSDEKD-ED---EDFLPLD-A-----TPPKTKIPPKNTKK-ALKPQKSST
SVV------DLE---------SDVKDSVPASPGAPAAPAADFPAETEQL-KPSSKKTVGV
KKTTTKSQS-------------SVS-TAGTKK

PF08070 // ENSGT00390000016222_1_Domain_9 (1773, 1882)

RAAPKG-TK-----SDSALSTHVS-EKP
APAKAKN-SRKRKPSSSDSSDSDFEKAISKGATSKKSKGEE-QDFRVD------LEDTMA
PRAKSGR-------ARKPIKYLEESDDDDD--DLF---

---------MEVAPLQPLNDNMQISKTKKNEDAKKRLSIERIYQKKT-QLEHILL-----
---------RP---DTYI--GSVELVTQPMWVYDEDVGINYRDV

PF02518 // ENSGT00390000016222_1_Domain_0 (105, 255)

TYVPGLYKIFDEILVN
AADNKQRDPKMSCIRITIDPENNLISIWNNGKGIPVVEHKVEKMYVSALIFGQLLTSSNY
DDDEKKVTGGRNGYGAKLCNIFSTKFTVETASKEYKKKFKQAMTWMDNMGKAGEMELKPF
SGEDYTCITFQPDLSKFKMQSLDKDIVALMVRRAYDIAGSTRDVKVFLNGSTLP------
--VKGFRSYVDMYLKDKVDETGNSKVXXXXXXXXXXXXXXXXXXXX--------------
----------------------XXXXXXXXXXXXXMARHVDYVVDQIVAK-VDVVKKKNK
GGVAVKAHQHXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-----------------
---------------XXXXX--------------------------XXXXXXXXXXXX--
----------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXX------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDAAIS
LAF-SKKQIDDRKEWLTHFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNS
DNE

PF00521 // ENSGT00390000016222_1_Domain_6 (964, 1448)

RSIPSMVDGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTII
N--LAQNFVGSNNLNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLARLLFPTKDDYTLK
FLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWSCKIPNFDVREVVNNIRRLMDGEEPLP
MLPSYKNFKGTIEELASNQYVISGEVAILNSTTIEISELPIRTWTQTYKEQVLEPMLNGT
EKTPPLITDYREYHTD-TTVKFVVKMTEEKLAEAERAGLHKIFKLQTSLTCNSMVLFDHV
GCLKKYDTPLDILRDFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILE-IDGKIVIE
NKPKKELIKVLIQRGY-----D---SDPVKAWKEAQQKVPDE--EENEESDNEKETEKSD
SATDSGPTFNYLLD-MPLWYLTKEKKDELCKLRNEKEQELETLKRKSPSDLWKEDLATFV
DELEIVE

ENSGT00390000016222_1_Linker_6_9 (1448, 1773)

AKEKEDEQVGLSGKA---------GKGKGKKI--QK-VEVLPSPCGKRVIPRV
TTEMKAEAEKKIKRKIKSENTEGS-------PQEGNMEPDSLKQRLEKKQKKEL-----G
TKTKKQTTLPFKPIKKGKKRNPWSDSESDMSGDD-SNFDV---PPREREPRK-AARSKFT
MDLDSDEDFSDFNDT-----QDEDFTPSDAT-----SPPKAKTSPKNSNKGLKTQKSAK-
-----SDLDVEDAM-----------DNVP--LSSNTPA--DLPADT-EIINPVAKQNVTM
K------K--------ATTKSQSATSTTGTKK

PF08070 // ENSGT00390000016222_1_Domain_9 (1773, 1883)

RAAPKGTKK------GPGLNSDESPKKP
APAKSKNPRKRKP-STSDDSDSTFEKIISKAVTNKKSKGED---FQL------DLDSAVA
PRAKSGR-------AKKPIKYLEESDE---DDDLF---

---------XLSPLPQPTDENPRLP---KGDGAKKRLSVERIYQKKT-QLEHILL-----
---------RP---DTYI--GSVETVTQQMWVFDEDVGLNCRDV

PF02518 // ENSGT00390000016222_1_Domain_0 (105, 255)

TFVPGLYKIFDEILVN
AADNKQRDKNMSCIKVTIDPENNTISVWNNGKGIPVVEHKVEKVYVPALIFGQLLTSSNY
DDDEKKVTGGRNGYGAKLCNIFSTKFTVETACREYKKLFKQ--TWTDNMGKAGEMKLKYF
DGEDYTCVTFQPDL

ENSGT00390000016222_1_Linker_0_1 (255, 309)

SKFKMTILDKDIVALMSRRAYDIAGSTKDVKVFLNGKRLP------
--VKGFRS

PF00204 // ENSGT00390000016222_1_Domain_1 (309, 595)

YVDLYLKDKVDETGNALKVIHEEVNSRWEVCLTLSEKGFQQVSFVNSIATT-
----------------------------------KGGRHVDYVADQIVNKLIEVVKKKNK
NGVGVKPFQVKNHMWIFVNALIENPTFDSQTKENMTLQAKSFG-----------------
---------------STCKL--------------------------SEKFI-----KG--
----------------AV-GC-GIV-ES-ILN-WVK-FK-AQT-QLN-KKC-SAV-KHT-
KIK-GVP-KLD-DAND-AGS-KNS-IDC-TL-ILT-EGD-SAK-TL-AVS-GL-GVV-GR
-DKY-GVF-PL-RGK-ILN-VR-EAS-HKQ-IME-NAE-INN-IIK-IVG-LQY-KKN-Y
ED-RES-LKT-LRY-GKI-MI-MTD-QDQ-DGS-HIK-GL-LI-NFI-HH-NWP-SL-LR
H-NF-LEE-FIT-PII-KAS-KNK-EEI-AF-YSI-PEF-EEW-KNS-T-----QNYNSW
KIKYYKG------------------LGTSTSKEAKEYFADMAKHRIGFKYSGPEDDAAIT
LAF-SKKKVEERKEWLTNFMEDRRQRKLHGLPEEYLYGKDTNYLTYNDFINKELVLFSNS
DNERSIPSLVDGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEASLMMTII
N--LAQNFVGSNNLNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLARLLFPPMDDNVLK
FLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWSCKIPNFDIRETVNNIRRLMDGEEPLP
MLPSYKNFKGTIDELGPNQYVISGEVSILDSTTIEITELPVRTWTQTYKEQVLEPMLNGT
EKTPPLITDYKEYHTD-TTVKFVVKMSEEKLAEAEAVGLHKVFKLQTNLTCNSMVLFDHV
GFLKKYESPQDILKEFFELRLRYYGLRKEWLIGMLSAESAKLSNQARFILEKIDGKIVIE
NKPKKELIQVLIQRGY-----E---SDPVKAWKELQNKIEEE--EEEEEDE-----SNKE
SAAATGPDFNYLLN-MPLWYLTKEKKDELCKQRDNKEKELENLKCKSPCDLWKEDLAAFV
EELDAVEAKQMQDEMAGIAGKPLKVKGG----KTKVKKA--QL-PEVMPSAHGIRVVPRV
TAEMKADAEKRAKKKVKSEKNELDENQEGN--SSGDKESSSLKQRIAQKRNVVQ-----G
TK--RQATLPFKPVKKTKKRNPWSDSGSDSESDD-FEVLP----QRERVVRQAAAKIKPM
ISSDSDENFISSDEESEFQGHSEGSSESDTN-SKEKPAPKPRAAPKETSEKTAKAPKQK-
SVKGDIPVKGQAV----A------D----EDVSQA-PAGPSVSIPP--S-KAVPKKPAAT
K--KASAA--------K--DNQPSIMDILAKK

PF08070 // ENSGT00390000016222_1_Domain_9 (1773, 1883)

KAVPKSSKTAVKEEPLDSDARAADAKKP
GPTKGRKLTKRQPSS--SDSDSDFGVKPSKSVAAKKPKQEDSDSFTAELTARADSPTEAA
PRARPGR-------LKKPVQYLES----SD-DDMF---

---------MELSPLQPVNENMQLNK-KKNEDAKKRLSIERIYQKKT-QLEHILL-----
---------RP-D-T-YI--GSVELVTQQMWVYDEDVGINYREVTFV

PF02518 // ENSGT00390000016222_1_Domain_0 (108, 255)

PGLYKIFDEILVN
AADNKQRDPKMSCIRVTIDPENNLISIWNNGKGIPVVEHKVEKMYVPALIFGQLLTSSNY
DDDEKKVTGGRNGYGAKLCNIFSTKFTVETASKEYKKMFKQ--TWMDNMGRAGDMELKPF
NGDDYTCITFQPDLSKFKMQSLDKDIVALMVRRAYDIAGSTKDVKVFLNGNKLP------
--VKGFRSYVDMYLKDKLDETGNALKVVHEQVNPRWEVCLTMSEKGFQQISFVNSIATS-
----------------------------------KGGRHVDYVADQIVSKLVDVVKKKNK
GGVAVKAHQVKNHMWIFVNALIENPTFDSQTKENMTL-------------------Q-A-
-K--S-F--G-S--T--C-Q--L-S--E--K------------------FIKA-------
-----------------AISC-GIV-ES-ILN-WVK-FK-AQV-QLN-KKC-SAV-KHN-
RIK-GIP-KLD-DAND-AGSRNSTE--C-TL-ILT-EGD-SAK-TL-AVS-GL-GVV-GR
-DKY-GVF-PL-RGK-ILN-VR-EAS-HKQ-IME-NAE-INN-IIK-IVG-LQY-KKN-Y
ED-EDS-LKT-LRY-GKI-MI-MTD

PF00521 // ENSGT00390000016222_1_Domain_6 (746, 1436)

-Q---------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------LIKVLIQRGY-----D---SDPVKAWKEAQQKVPDE--EENEES----DNENSD
SVAESGPTFNYLLD-MPLWYLTKEKKDELCKQRNEKEQELNTLKKKSPSDLWKED

ENSGT00390000016222_1_Linker_6_9 (1436, 1771)

LAVFI
EELEVVEAKEKQDEQAGLPGKG---------GKAKGKKI--QM-SEVLPSPQGKRVIPQV
TVEMKAEAEKKIRKKIKSENVEGTP-------TENGLELGSLKQRIEKK--QKKE---TG
TMAKKQTTLSFKPVKKGKKRNPWSDSESDMSS-NESNFD---VPPREKDPRRAATKTKFT
MDLDSDEDFSGSDGKD-ED---EDFFPLD-T-----IPPKTKTSQRNTKK-ALKPQKSTM
S-A------DLE---------SDVQDSVPASPGPSA---ADSPADTEQL-APGSKQTVAV
KKTATKSQS-------------STST-AVT

PF08070 // ENSGT00390000016222_1_Domain_9 (1771, 1882)

KKRAVPKG-TK-----SDSALNAHGP-EKP
EPAKAKKSSRKRKQSSSDDSDSDFEKAVSKAALSKKPKEEN-QDFQVD------LDETIA
PRTKSGR-------ARKPIKYLEESDEDD----LF---

---------MEVSPLQPVNENMLINKTKKNEDAKKRLSIERIYQKKT-QLEHILL-----
---------RP-D-T-YI--GSVELVTQQMWVYDEDIGINYREVTFV

PF02518 // ENSGT00390000016222_1_Domain_0 (108, 255)

PGLYKIFDEILVN
AADNKQRDPKMSCIRVTIDPENNLISIWNNGKGIPVVEHKVEKMYVPALIFGQLLTSSNY
DDDEKKVTGGRNGYGAKLCNIFSTKFTVETASREYKKMFKQ--TWMDNMGRAGEMELKPF
NGEDYTCITFQPDLSKFKMQSLDKDIVALMVRRAYDIAGSTKDVKVFLNGNKLP------
--VKGFRSYVDMYLKDKVDETGNPLKIIHEQVNPRWEVCLTMSEKGFQQISFVNSIATS-
----------------------------------KGGRHVDYIADQIVTKLVEVVKKKNK
GGVAVKAHQVKNHMWIFVNALIENPTFDSQTKENMTL-------------------Q-V-
-K--S-F--G-S--T--C-H--L-S--E--K------------------FIKA-------
-----------------AIGC-GIV-ES-ILN-WVK-FK-AQV-QLN-KKC-SAV-KHN-
RIK-GIP-KLD-DAND-AGGRNSNE--C-TL

PF01751 // ENSGT00390000016222_1_Domain_3 (632, 769)

-ILT-EGD-SAK-TL-AVS-GL-GVV-GR
-DKY-GVF-PL-RGK-ILN-VR-EAS-HKQ-IME-NAE-INN-IIK-IVG-LQY-KKN-Y
ED-EDS-LKT-LRY-GKI-MI-MTD-QDQ-DGS-HIK-GL-LI-NFI-HH-NWP-SL-LR
H-RF-LEE-FI-TPIV-KVS-KNK-QEMAFYSL---PEF-EEWKSST-------PNHKKW
KVKYYKG------------------LGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAIS
LAF-SKKQIDDRKEWLTHFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNS
DNE

PF00521 // ENSGT00390000016222_1_Domain_6 (964, 1436)

RSIPSMVDGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTII
N--LAQNFVGSNNLNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLARLLFPPKDDHTLK
FLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWSCKIPNFDIREVVNNIRRLMDGEEPLP
MLPSYKNFRGTIEELAPNQYVISGEVAILNSTTIEISELPIRTWTQTYKEQVLEPMLNGT
EKTPPLITDYREYHTD-TTVKFVVKMTEEKLAEAERVGLHKVFKLQTSLTCNSMVLFDHV
GCLKKYDTVLDILRDFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIE
NKPKKELIKVLIQRGY-----D---SDPVKAWKEAQQKVPDE--EENEESDNENEAEKGD
SVKDSGPTFNYLLD-MPLWYLTKEKKDELCKLRNEKEQELETLKRKSPSDLWKED

ENSGT00390000016222_1_Linker_6_9 (1436, 1773)

LAAFI
EELEAVETKEKQEEQIGLPGKG---------GKAKGKKI--QM-AEVLPSPCGKRVIPRV
TIEMKAEAEKKIKKKIKSENTEGSP-------QEDGMELEGLKQRLEKK--QKRE---PG
TKTKKQTTLPFKPVKKGKKRNPWSDSESDMSS-NESDFD---VPPREIEPRRAATKTKFT
VDLDSDDDFSDFDEKT-QD---EDFVPS-DV-----SPVKTKTSPPVPTN-K----ELKP
QKSA-TSVMDLDA--------GGAKDSGPPSLDSPAA---DFSAETEII-NPVSKKKVAV
KKTA-AKSQ-------------SSTSTAGAKK

PF08070 // ENSGT00390000016222_1_Domain_9 (1773, 1882)

RAAPKG-TK-----KEPGLNSDVS-QKP
DPPKTK-NRRKRKPSTSDDSDSNFEKMISKTVTSKKSKGES-EDFHLD------LDSAVA
PRAKSGR-------AKKPIKYLEESDEDDLF-------

-----MDLDESFSPLKTVDVNPKVDKI-KNEDSKKRLSVERIYQKKT-QLEHILL-----
---------RP---DTYI--GSVEQVTQQMWVFDEEIGLNCRDVTFV

PF02518 // ENSGT00390000016222_1_Domain_0 (108, 243)

PGLYKIFDEILVN
AADNKQRDKKMSCIKITIDPENNTVSVWNNGKGIPVVEHKVEKVYVPALIFGQLLTSSNY
DDDEKKVTGGRNGYGAKLCNIFSTKFTVETACREYKKRFQQ--TWSNNMGKAGEMKLKYF
DGEDFTCITFQPDLAKFKMTTLDKDIVALMSRRAYDIAGASNGVTVFLNGNKLP------
--VRGFRSYVDLYIKDKVDETGNLLKIIHEEVNSRWEVCLTMSEKGFQQVSFVNSIATT-
----------------------------------KGGRHVDYVADQIVNKLIDVVKRRNK
GGVAVKPFQVKNHMWIFINCLIENPTFDSQTKENMTLQAKSFG-----------------
---------------STCKL--------------------------SEKFI-----KG--
----------------AV-SC-GIV-EN-ILN-WVK-FK-AQN-QLN-KKC-SAV-KHT-
RIK-GIP-KLD-DAND-AGS-KNS-INC-TL-ILT-EGD-SAK-TL-AVS-GL-GVV-GR
-DRY-GVF-PL-RGK-MLN-VR-EAS-HKQ-IME-NAE-INN-IIK-IVG-LQY-KKT-Y
DD-EES-LRT-LRY-GKI-MI-MTD-QDQ-DGS-HIK-GL-LI-NFI-HH-NWP-SL-LR
H-RF-LEE-FIT-PIV-KVS-KNK-EEI-SF-YSI-PEF-EEW-KSS-N-----SNYRNW
KTKYYKG------------------LGTSTSKEAKEYFAEMTRHRIPFKYSGPEDDAAIT
LAF-SKKKIDDRKEWLTSFMEDRRQRKLHGLPDVYLYGKSTTYLTYNDFINKELVLFSNS
DNE

PF00521 // ENSGT00390000016222_1_Domain_6 (964, 1436)

RSIPSLVDGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGETSLMMTII
N--LAQNFVGSNNLNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLARLAFPVLDDNVLK
FLFDDNQRVEPEWYIPIIPMVLINGAEGIGTGWSCKIPNYDVREVVNNIRRMLDGDEPLP
MMPNYKNFKGTIDSVGQNQYVVNGEVSIIDSTTIEISELPVRTWTQVYKEQVLEPMLNGT
EKTPPLITDYKEYHTD-TTVRFVIKMSEQKLAEAEAAGLHKVFKLQSSLACPNMVLFDHI
GCLKKYETAEDILREFYELRLRYYSLRKDWLVGMLGAESAKLNNQARFILEKIEGKIVIE
NKPKKELIKVLIQRGY-----D---SDPVKKWKESQQKGSDD--DSNEEGESEK---ENE
PDASTGPDFGYLLN-MPLWYLTKEKKDELCKQRDDKETELETLKRKSPDDLWRHD

ENSGT00390000016222_1_Linker_6_9 (1436, 1777)

LAVFV
EALDIQEEKEKQDELLGTSKAT-K----GKGGKVKV-KK--QL-QEVMPSPVGRRVIPRV
TEDMKAGAEKKLKRKIKTEKNELDGKQKED-SLECDKEPKSLKQRLTKKCKTEP-----D
AK--KQSVLPFKPVKKAMTRNPWSDSESDGNDFD-VSGIVEAAPHANLSHRQTTAKATYS
LDSDSDSFLSHTSGK--LQDQEEMMEDAALGENAEVPNPKLKTVSKKAKESKGKEESKPS
EVQSAATINLLE-------------------SSLDEKAKPATSLNV--ASKPPLKRKGPA
---KKASN--------AAEDNQLSIMDAFSKKKVTA

PF08070 // ENSGT00390000016222_1_Domain_9 (1777, 1883)

KTSKTAVKSSDSGT--DGAASKNP
VPAKKKKPVKRRPFSDSEDSDSDFGQLVKKTTAAKKSKMMD-DSFSVD----SDIDSPVA
PRERGGR-------SRKPIQYLEESD-----DEIL---

---------MEVSPLQXXXXXXXXXXXXXXXXXXXXXXXXX--------XXXXXX-----
XX-------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXN
AADNKQRDPKMSCIRVTIDPEKKFNSI-DNGKSFSVCVHKDEKMYFPALSVGHLLTLSN

PF02518 // ENSGT00390000016222_1_Domain_0 (180, 255)

Y
DDDEKKVTGGRNGYGAKLCNIFSTKFTVETASREYKKMFKQVKTWMNNMGKAGDMELKPF
NGEDYTCITFQPDL

ENSGT00390000016222_1_Linker_0_1 (255, 309)

AKFKMQSLDKDIVALMVRRAYDIAGSTKDVKVFLNGNKLP------
--IKGFRS

PF00204 // ENSGT00390000016222_1_Domain_1 (309, 470)

YVDMYLKDKVDETGNPLKIIHEQVNHRWEVCLTMSEKGFQQISFVNSIATS-
----------------------------------KGGRHVDYIADQIVAKLVEVVKKKNK
GGIAVKAHQCXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXATGC-GIV-ES-ILN-WVK-FK-AQV-QLN-KKC-SAV-KHN-
RIK-GIP-KLD-DAND-AGGRNSTD--C-TL-ILT-EGD-SAK-TL-AVS-GL-GVV-GR
-DKY-GVF-PL-RGK-ILN-VR-EAS-HKQ-IME-NAE-INN-IIK-IVG-LQY-KKN-Y
ED-EDS-LKS-LRY-GKI-MI-MTD-QDQ-DGS-HIK-GL-LI-NFI-HH-NWP-SL-LR
H-RF-LEE-FI-TPIV-KVS-KNK-QEISFYSL---PEF-EEWKSSN-------PNHRKW
KVKYYKG------------------LGTSTSKEAKEYFSDMKRHRIQFKYSGPEDDAAIS
LAF-SKKQTDDRKEWLTHFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNS
DNERSIPSMVDGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTII
N--LAQNFVGSNNLNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLARLLFPPKDDHTLR
FLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWSCKIPNFDVREVVNNIRRLMDGEEPLP
MVPGYKNFKGTIEELAPNQYVISGEVAILNSTTIEITELPIRTWTQTYKEQVLEPMLNGT
EKTPPLITDYREYHTD-TTVKFVVKMTEEKLAQAERAGLHKVFKLQSSLTCNSMVLFDHV
GCLKKYDTVLDILRDFYELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIE
NKPKKELIKVLIQRGY-----D---SDPVKAWKEAQQK-PDE--EENEESDNEKESEKSD
SVTDSGPTFNYLLD-MPLWYLTKEKKDELCKLRKEKEEELEILKRKSPADLWREDLAAFV
EELEXXXXXXXXXXXXXXXXXX---------XXXXXXXX--XXXX-XXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXNENTEGSP-------QENG-EAEGLKKRLEKKLKKEKE---PG
AKTMKQTTLSFKPVKKGKKKNPWSDSESDMSS-DESDFD---VPPREIELRKASTKTKTM
VDLDSDENFSDFDEKY-QDEDDGDFVPSDDS-----L-PTTKTSQKNYNK-EQKPPK---
-----SAVSDIDA--------DDAKNDVPLSPSPPAA---DFTAKTET-VEPISKKKVTV
KKTAA-KSQ-------------SSTTTAGTKK

PF08070 // ENSGT00390000016222_1_Domain_9 (1773, 1883)

RGAPKV-TK-----KDSGLNSETS-KKP
DPTKTK-IRRKRKPSSSDDSDSNFEERISKAAASKKSKGET-NDFHQD------LDSALA
PRAKSGR-------AKKPIKYLEESDDDDDLF------

---------MEVSPLQPVHENMQMNK-KKNEDPKKRLSIERIYQKKT-QLEHILL-----
---------RP-D-T-YI--GSVELVTQQMWVYDEDVGINYREVTFV

PF02518 // ENSGT00390000016222_1_Domain_0 (108, 255)

PGLYKIFDEILVN
AADNKQRDPKMSCIRVTIDPENNLISIWNNGKGIPVVEHKVEKMYVPALIFGQLLTSSNY
DDDEKKVTGGRNGYGAKLCNIFSTKFTVETASKEYKKMFKQ--TWMDNMGRAGDMELKPF
SGEDYTCITFQPDL

ENSGT00390000016222_1_Linker_0_1 (255, 305)

SKFKMQSLDKDIVALMVRRAYDIAGSTKDVKVFLNGNKLP------
--VK

PF00204 // ENSGT00390000016222_1_Domain_1 (305, 590)

GFRSYVDMYLKDKLDETGNPLKVVHEQVNPRWEVCLTMSEKGFQQISFVNSIATS-
----------------------------------KGGRHVDYVADQIVSKLVDVVKKKNK
AGVAVKAHQVKNHMWIFVNALIENPTFDSQTKENMTL-------------------Q-A-
-K--S-F--G-S--T--C-Q--L-S--E--K------------------FIKA-------
-----------------AIGC-GIV-ES-ILN-WVK-FK-AQV-QLN-K

ENSGT00390000016222_1_Linker_1_3 (590, 632)

KC-SAV-KHN-
KIK-GIP-KLD-DAND-AGSRNSAE--C-TL

PF01751 // ENSGT00390000016222_1_Domain_3 (632, 769)

-ILT-EGD-SAK-TL-AVS-GL-GVV-GR
-DKY-GVF-PL-RGK-ILN-VR-EAS-HKQ-IME-NAE-INN-IIK-IVG-LQY-KKN-Y
ED-EDS-LKT-LRY-GKI-MI-MTD-QDQ-DGS-HIK-GL-LI-NFI-HH-NWP-SL-LR
H-RF-LEE-FI-TPIV-KVS-KNK-QEIAFYSL---PEF-EEWKSST-------PNHKKW
KVKYYKG------------------LGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAIS
LAF-SKKQTDDRKEWLTNFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNS
DNERSIPSMVDGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTII
S--LAQNFVGSNNLNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLTRLLFPLKDDHTLK
FLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWSCKIPNFDIREVVNNIRRLMDGEEPLP
MLPSYKNFKGTIEELASNQYVINGEVAILNSTTIEISELPIRVWTQTYKEQVLEPMLNGT
EKTPPLITDYREYHTD-TTVKFVVKMTEEKLAEAERVGLHKVFKLQTSLTCNSMVLFDHV
GCLKKYDTVLDILRDFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIE
NKPKKELIKVLIQRGY-----D---SDPVKAWKEAQQKVPDE--EENEESDN----EKSD
SVTDSGPTFNYLLD-MPLWYLTKEKKDELCKQRNEKEQELDTLKRKSPSDLWKEDLAAFI
EELESIEAKEKQDEQVGLPGKG---------GKAKGKKA--QA-SEVLPSPHGKRVIPQV
TMEMKAGAEKKIKKKIKSENIEGTP-------NEDGLELEGLKQRLGKK--QKRE---PG
TK--KQTTLPFKPIKKGKKRNPWSDSESDMSS-TESNFD---VPPRETEPRRAAAKTKFT
MDLDSDEDFSDFDEK-NED---EDFLPSD-A-----SPPKTKTPPKNTKK-ALKPQKS--
TM----SVVDLET--------DDIKDSVPPSPSPPVA---NFPVETEVL-KLPSKKNVTV
KKTA-TKSQ-------------STTSTAG

PF08070 // ENSGT00390000016222_1_Domain_9 (1770, 1882)

TKKKTAPKG-TK-----SDSALYSGSL-GKP
EPAKTK-IRRKRKPSTSDDSDSNFEKIISKAATSKKPKGES-EAFHLD------VDSAVA
PRAKSGR-------AKKPIKYLEESDEDDLF-------

----MAAGMEDLSPLQPVNENLQINKIKKNEDAKKRLSVERIYQKKT-QLEHILL-----
---------RP---DTYI--GSVEVVTQQMWVYDEEVGLNYRDVTFV

PF02518 // ENSGT00390000016222_1_Domain_0 (108, 253)

PGLYKIFDEILVN
AADNKQRDPKMNCIKVTIDSENNTISIWNNGKGIPVVEHKVEKVYVPALIFGQLLTSSNY
DDDEKKVTGGRNGYGAKLCNIFSTRFTVETACKEYKKLFKQ--TWRDNMGKAGEMTLKPF
SGEDYTCITFQPDLSKFKMTNLDKDIVALMSRRAYDIAGSTKDVKVFLNGNRLP------
--VKGFRSYVDLYVKDKLDETGNPLKIIHEEVNNRWEVCLTMSEKGFQQISFVNSIATS-
----------------------------------KGGRHVDYVADQIISRLIDVVKKKNK
GGVAVKAHQVKNHMWIFVNALIENPTFDSQTKENMTLQAKSFG-----------------
---------------SKCEL--------------------------SEKFI-----KA--
----------------AI-GC-GIV-ES-ILN-WVK-FK-AQV-QLN-KKC-SAV-KHN-
RIK-GIP-KLD-DAND-AGS-KNS-TDC-TL-ILT-EGD-SAK-TL-AVS-GL-GVV-GR
-DKY-GVF-PL-RGK-ILN-VR-EAS-HKQ-IME-NAE-INN-IIK-IVG-LQY-KKN-Y
ED-ADS-LKS-LRY-GKI-MI-MTD-QDQ-DGS-HIK-GL-LI-NFI-HH-NWP-SL-LR
H-CF-LEE-FIT-PIV-KVS-RNK-QEL-SF-YSL-PEF-EEW-KNS-T-----ENHKKW
KVKYYKG------------------LGTSTSKEAKEYFSDMSRHRIQFKYSGPEDDAAIS
LAF-SKKQIDDRKEWLTHFMEDRRQRKLLGLPEDYLYGKATKHLTYNDFINKELILFSNS
DNE

PF00521 // ENSGT00390000016222_1_Domain_6 (964, 1436)

RSIPSMVDGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTII
N--LAQNFVGSNNLNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLARLLFPAKDDQTLK
FLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWSCKIPNFDVREVVNNIRRLMDGEEPLP
MLPSYKNFKGTIDELAPNQYIISGEVSILNSTTIEISELPVRTWTQVYKEQVLEPMLNGT
DKTPPLITDYREYHTD-TTVKFIVKMTEEKLAQAEHAGLHKVFKLQTNLTCNSMVLFDHV
GCLKKYDTALDILKDFFDLRLKYYGLRKEWLTGMLGAESARLNNQARFILEKIEGKIVIE
NKPKKELIKVLIQRGY-----D---SDPVKAWKEAQQKSPGDNEDENEESENEKETEKGD
SATDSGPTFNYLLD-MPLWYLTKEKKDELCRQRTEKEQELETLKRKSPSDLWRED

ENSGT00390000016222_1_Linker_6_9 (1436, 1773)

LAAFV
EELEVVEAKEKRDEQVGAVGKG------KAGAKPKAKKG--QL-AEILPSPCGRRVVPRV
TVEMKAEAEKKIRKKIKTENIEESS-------QDDSIEPETLKQRLNKKLKTEP-----G
TKQKKQTKLPFKPIKKENKKNPWSDSESDMSCNE-NDFYV--PPRETKLRRTAAANTKYT
VDLDSDSDISDSKEELQDE--DDDFIPSDGSSSQVKS------MPKTTKGQTTSKEEEPQ
KSST-LSDEVED---------LEPEETKNLALASSSSSAFDFPVEL-EITDPVPKKSVPV
K------K--------TATKNQSSTSTAAPKK

PF08070 // ENSGT00390000016222_1_Domain_9 (1773, 1883)

RAAPKTSKKALASKGSPDS-ISEASEKI
VPAKGKKPRKRKP-SSSDDSDSDFGKSISTAKSGKKSKKVD-DDFEIDS---NSSSMPMA
PRARPGR-------AKKPIKYLEESD----EDDMF---

---------MELSPLQPVNENMLMNK-KKNEDGKKRLSIERIYQKKT-QLEHILL-----
---------RP-D-T-YI--GSVELVTQQMWVYDEDVGINYREVTFV

PF02518 // ENSGT00390000016222_1_Domain_0 (108, 255)

PGLYKIFDEILVN
AADNKQRDPKMSCIRVTIDPENNVISIWNNGKGIPVVEHKVEKIYVPALIFGQLLTSSNY
DDDEKKVTGGRNGYGAKLCNIFSTKFTVETASREYKKMFKQ--TWMDNMGRAGDMELKPF
SGEDYTCITFQPDL

ENSGT00390000016222_1_Linker_0_1 (255, 305)

SKFKMQSLDKDIVALMVRRAYDIAGSTKDVKVFLNGNRLP------
--VK

PF00204 // ENSGT00390000016222_1_Domain_1 (305, 590)

GFRSYVDLYLKDKVDETGNSLKVIHEQVNPRWEVCLTMSERGFQQISFVNSIATS-
----------------------------------KGGRHVDYVADQIVSKLVDVVKKKNK
GGVAVKAHQVKNHMWIFVNALIENPTFDSQTKENMTL-------------------Q-A-
-K--S-F--G-S--T--C-Q--L-S--E--K------------------FIKA-------
-----------------AIGC-GIV-ES-ILN-WVK-FK-AQI-QLN-K

ENSGT00390000016222_1_Linker_1_3 (590, 632)

KC-SAV-KHT-
KIK-GIP-KLD-DAND-AGSRNSTE--C-TL

PF01751 // ENSGT00390000016222_1_Domain_3 (632, 769)

-ILT-EGD-SAK-TL-AVS-GL-GVV-GR
-DKY-GVF-PL-RGK-ILN-VR-EAS-HKQ-IME-NAE-INN-IIK-IVG-LQY-KKN-Y
ED-EDS-LKT-LRY-GKI-MI-MTD-QDQ-DGS-HIK-GL-LI-NFI-HH-NWP-SL-LR
H-RF-LEE-FI-TPIV-KVS-KNK-QEIAFYSL---PEF-EEWKSST-------PNHKKW
KVKYYKG------------------LGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAIS
LAF-SKKQVDDRKEWLTNFMEDRRQRKLLGLPEDYLYGQSTSYLTYNDFINKELILFSNS
DNERSIPSMVDGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTII
N--LAQNFVGSNNLNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLARLLFPPKDDHTLR
FLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWSCKIPNFDVREVVNNIRRLLDGEEPLP
MLPSYKNFKGTIEELASNQYVINGEVAILDSTTIEISELPIRTWTQTYKEQVLEPMLNGT
EKTPSLITDYREYHTD-TTVKFVIKMTEEKLAEAERVGLHKVFKLQSSLTCNSMVLFDHV
GCLKKYDTVLDILRDFFELRLKYYGLRKEWLLGMLGAESSKLNNQARFILEKIDGKIVIE
NKPKKELIKVLIQRGY-----D---SDPVKAWKEAQQKVPDE--EENEESDT--ETSTSD
SAAEAGPTFNYLLD-MPLWYLTKEKKDELCKQRNEKEQELNTLKQKSPSDLWKEDLAVFI
EELEVVEAKEKQDEQVGLPGKA---------GKAKGKRA--QMCADVLPSPRGKRVIPQV
TVEMKAEAEKKIRKKIKSENVEGTP-------AEDGAEPGSLQQRIEKK--QKRE---PG
--AKKQTTLPFKPIKKGKKKNPWSDSESDMSS-NESNVD---VPPREKEQRRAAAKAKFT
VDLDSDEEFSGLDEKD-ED---EDFLPLD-A-----TPPKAKIPPKNTKK-ALKTKGSSM
SVV------DLE---------SDVKDSVPASPGVPA---ADFPAETEQS-KPSK-KTVGV
KKTATKSQS-------------SVS-TAGTKKR

PF08070 // ENSGT00390000016222_1_Domain_9 (1774, 1882)

AAPKG-TK-----SDSALSARVS-EKP
APAKAKN-SRKRKPSSSDSSDSDFERAISKGATSKKARGEK-QDFPVD------LEDTIA
PRAKSER-------ARKPIKYLEESDDNDDDDDLF---

---------MEVSPLQPVNENMQVNKIKKNEDAKKRLSIERIYQKKT-QLEHILL-----
---------RP-D-T-YI--GSVELVTQQMWVYDEDVGINYREVTFV

PF02518 // ENSGT00390000016222_1_Domain_0 (108, 255)

PGLYKIFDEILVN
AADNKQRDPKMSCIRVTVDPENNLISIWNNGKGIPVVEHKVEKVYVPALIFGQLLTSSNY
DDDEKKVTGGRNGYGAKLCNIFSTKFTVETASREYKKMFKQ--TWIDNMGRAGEMELKPF
NGEDYTCITFHPDL

ENSGT00390000016222_1_Linker_0_1 (255, 305)

SKFKMQSLDKDIVALMVRRAYDIAGSTKDVKVFLNGNKLP------
--VK

PF00204 // ENSGT00390000016222_1_Domain_1 (305, 590)

GFRSYVDMYLKDKVDETGNPLKVIHEQVNHRWEVCLTMSEKGFQQISFVNSIATS-
----------------------------------KGGRHVDYVADQIVTKLVDVVKKKNK
GGVAVKAHQVKNHMWIFVNALIENPTFDSQTKENMTL-------------------Q-P-
-K--S-F--G-S--T--C-Q--L-S--E--K------------------FIKA-------
-----------------AIGC-GIV-ES-ILN-WVK-FK-AQV-QLN-K

ENSGT00390000016222_1_Linker_1_3 (590, 632)

KC-SAV-KHN-
RIK-GIP-KLD-DAND-AGGRNSTD--C-TL

PF01751 // ENSGT00390000016222_1_Domain_3 (632, 769)

-ILT-EGD-SAK-TL-AVS-GL-GVV-GR
-DKY-GVF-PL-RGK-MLN-VR-EAS-HKQ-IME-NAE-INN-IIK-IVG-LQY-KKN-Y
ED-EDS-LKT-LRY-GKI-MI-MTD-QDQ-DGS-HIK-GL-LI-NFI-HH-NWP-SL-LR
H-RF-LEE-FI-TPIV-KVS-KNK-QEVSFYSL---PEF-EEWKSST-------PNHKKW
KVKYYKG------------------LGTSTSKEAKEYFADMTRHRIRFKYSGPEDDAAIS
LAF-SKKQVDDRKEWLTHFMEDRRQRKLLGLSEDYLYGQTTTYLTYNDFINKELILFSNS
DNERSIPSMVDGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTII
N--LAQNFVGSNNLNLLQPIGQFGTRLHGGKDSASPRYIFTMLSSLARLLFPPKDDHTLK
FLYDDNQRVEPEWYIPIIPMVLVNGAEGIGTGWSCKIPNFDVREVVNNIRRLMDGEEPLP
MLPSYKNFRGTIEELAPNQYVISGEVAILNSTTIEISELPIRTWTQTYKEQVLEPMLNGT
EKTPPLITDYREYHTD-TTVKFVVKMTEEKLAEAERVGLHKVFKLQTSLTCNSMVLFDHV
GCLKKYDTVLDILRDFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIVIE
NKPKKELIKVLIQRGY-----D---SDPVKAWKEAQQKVPDE--EENEESDDEQETEKGS
SVTDSGPSFNYLLD-MPLWYLTKEKKDELCKLRNEKEQELDTLKRKCPSDLWKEDLAVFI
EELEAVEAKEKKDEQIGLPGKA---------GKAKGKKA--QM-TEVLPSPHGQRVIPRV
TLEMKAEAEKKSKKKIKTENTEGSP-------QEDGMVTESLKQRLEKK--QKRE---PG
TKTKKQTTLPFKPVKKGKKKNPWSDSESDMSS-SESNFD---VPPREKELCRAATKAKFT
MDLDSDADFSDFDEK-TQD---EDFVPSD-A-----SPPKTKTSPKHTNK-ELKPQK---
SAVSDTEAD--G---------TK--GSAPLSSSPLAA---DFPDETEMI-NPISKKKVTA
KKMAA-KSQ-------------SSTSTTTTKK

PF08070 // ENSGT00390000016222_1_Domain_9 (1773, 1882)

RAAPKR-AK-----KDVALNPGAS-QKP
DPAKTK-SRRKRKPSTSDDSDSNFEKVISKALTSKKSKGES-DDFHLD------IDEAVA
PRARSVR-------AKKPIQYLEESDEDDLF-------

-----MELLDSPAPLRPLHDNPRLP---KADGAQKRLSVERIYQKKT-QLEHILL-----
---------RP---DTYI--GSVETVTQQMWVFDEDVGLNCRDVTFV

PF02518 // ENSGT00390000016222_1_Domain_0 (108, 255)

PGLYKIFDEILVN
AADNKQRDKSMSCIKVTIDPENNTISVWNNGKGIPVVEHKVEKVYVPALIFGQLLTSSNY
DDDEKKVTGGRNGYGAKLCNIFSTKFTVETACREYKKLFKQ--TWTDNMGKAGEMTLKHF
DGEDYTCVTFQPDLSKFKMTILDKDIVALMSRRAYDIAGSTKDVKVFLNGKRLP------
--VKGFRSYVDLYLKDKVDETGNALKVIHEEVNSRWEVCLTLSEKGFQQVSFVNSIATTK
VILSSCSHIHFIFFLLALCFVSLETPQALWSRFPLGGRHVDYVADQIVTKLIDVVKKKNK
NGVGVKPFQVKNHMWIFVNSLIENPTFDSQTKENMTLQAKSFG-----------------
---------------STCKL--------------------------SEKFI-----KG--
----------------AV-GC-GIV-ES-ILN-WVK-FK-AQT-QLN-KKC-SAV-KHT-
KIK-GVP-KLD-DAND-AGS-KNS-IDC-TL

PF01751 // ENSGT00390000016222_1_Domain_3 (632, 769)

-ILT-EGD-SAK-TL-AVS-GL-GVV-GR
-DKY-GVF-PL-RGK-MLN-VR-EAS-HKQ-IME-NAE-INN-IIK-IVG-LQY-KKN-Y
ED-RES-LKS-LRY-GKI-MI-MTD-QDQ-DGS-HIK-GL-LI-NFI-HH-NWP-SL-LR
H-NF-LEE-FIT-PII-KVS-KNK-EEI-PF-YSI-PEF-EEW-KSS-T-----QNYNSW
KIKYYKG------------------LGTSTSKEAKEYFADMARHRIGFKYSGPEDDAAIT
LAF-SKKKVEERKEWLTNFMEDRRQRKLHGLPEDYLYGKDTNYLTYNDFINKELVLFSNS
DNE

PF00521 // ENSGT00390000016222_1_Domain_6 (964, 1436)

RSIPSLVDGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEASLMMTII
N--LAQNFVGSNNLNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLARLLFPPVDDNVLR
FLYDDNQRVEPEWYMPIIPMVLINGAEGIGTGWSCKIPNFDIRETVNNIRCLLDGKEPLP
MLPSYKNFKGTIDELGPNQYVISGEVSILDSTTIEITELPVRTWTQTYKEQVLEPMLNGT
EKTPPLITDYKEYHTD-TTVKFVVKMSEEKLAEAEAVGLHKVFKLQTNLTCNSMVLFDHV
GFLKKYESPQDILKEFFELRLRYYGLRKEWLIGMLGAESAKLNNQARFILEKIDGKIVIE
NKPKKELIQVLIQRGY-----E---SDPVKAWKELQNKEEEE------GDE-----SGEE
SAAATGPDFNYLLN-MPLWYLTKEKKDELCKQRDNKDKELEDLKHKSPSDLWKED

ENSGT00390000016222_1_Linker_6_9 (1436, 1773)

LAAFV
EELDAVEAKQMQDEMAGITGKPLKVKGGKQGGKQKVTKA--QL-AEVMPSPHGIRVVPRV
TAEMKAEAEKRIKKKIKSEKNESDEKQEGN--SSGDKEPSSLKQRLAQKRKAEQ-----G
TK--RQTTLPFKPIKKM-KRNPWSDSESDSESDD-FEVPS----KRERVVRQAAAKIKPM
VNSDSDADLTSSDEDSEYQENSEGNTDSDTT-SKKKPP-KAKAVPK---EKKGKAPKEK-
PLPDAVPVRVQDV----A------A----ESASQD-PAAPPVSVPR--A-QAVPKKPAAA
K--KGSTA--------K--DNQPSIMDILTKK

PF08070 // ENSGT00390000016222_1_Domain_9 (1773, 1876)

KAAPKAPRAAQREESPPSEATAAVAKKP
GPPRAERTKR---LTSSSDSDSDFGSRPSKSVAAKKSKRDDDDSYSIDLTA--DSPAAAA
PRTRPGR-------MRMICSEFYEVLSHWDTD------

---------MEVSPLQPVNENMQVNKIKKNEDAKKRLSIERIYQKKT-QLEHILL-----
---------RP-D-T-YI--GSVELVTQQMWVYDEDVGINYREVTFV

PF02518 // ENSGT00390000016222_1_Domain_0 (108, 255)

PGLYKIFDEILVN
AADNKQRDPKMSCIRVTIDPENNLISIWNNGKGIPVVEHKVEKMYVPALIFGQLLTSSNY
DDDEKKVTGGRNGYGAKLCNIFSTKFTVETASREYKKMFKQ--TWMDNMGRAGEMELKPF
SGEDYTCITFQPDLSKFKMQSLDKDIVALMVRRAYDIAGSTKDVKVFLNGNKLP------
--VKGFRSYVDMYLKDKLDETGNPLKVIHEQVNHRWEVCLTMSEKGFQQISFVNSIATS-
----------------------------------KGGRHVDYVADQIVTKLVDVVKKKNK
GGVAVKAHQVKNHMWIFVNALIENPTFDSQTKENMTL-------------------Q-P-
-K--S-F--G-S--T--C-Q--L-S--E--K------------------FIKA-------
-----------------AIGC-GIV-ES-ILN-WVK-FK-AQV-QLN-KKC-SAV-KHN-
RIK-GIP-KLD-DAND-AGGRNSTD--C-TL

PF01751 // ENSGT00390000016222_1_Domain_3 (632, 769)

-ILT-EGD-SAK-TL-AVS-GL-GVV-GR
-DKY-GVF-PL-RGK-MLN-VR-EAS-HKQ-IME-NAE-INN-IIK-IVG-LQY-KKN-Y
ED-EDS-LKT-LRY-GKI-MI-MTD-QDQ-DGS-HIK-GL-LI-NFI-HH-NWP-SL-LR
H-RF-LEE-FI-TPIV-KVS-KNK-QEMAFYSL---PEF-EEWKSST-------PNYKKW
KVKYYKG------------------LGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAIS
LAF-SKKQIDDRKEWLTNFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNS
DNE

PF00521 // ENSGT00390000016222_1_Domain_6 (964, 1436)

RSIPSMVDGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTII
N--LAQNFVGSNNLNLLQPIGQFGTRLHGGKDSASPRYIFTMLSSLARLLFPPKDDHTLK
FLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWSCKIPNFDVREVVNNIRRLMDGEEPLP
MLPSYKNFKGTIEELAPNQYVISGEVAILNSTTIEISELPIRTWTQTYKEQVLEPMLNGT
EKTPPLITDYREYHTD-TTVKFVVKMTEEKLAEAERVGLHKVFKLQTSLTCNSMVLFDHV
GCLKKYDTVLDILRDFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIE
NKPKKELIKVLIQRGY-----D---SDPVKAWKEAQQKVPDE--EENEESDNEKETEKSD
SVTDSGPTFNYLLD-MPLWYLTKEKKDELCRLRNEKEQELDTLKRKSPSDLWKED

ENSGT00390000016222_1_Linker_6_9 (1436, 1773)

LATFI
EELEAVEAKEKQDEQVGLPGKG---------GKAKGKKT--QM-AEVLPSPCGQRVIPRI
TIEMKAEAEKKNKKKIKNENTEGSP-------QEDGMELEGLKQRLEKK--QKRE---PG
TKTKKQTTLPFKPIKKGKKRNPWSDSESDRSS-DESNFD---VPPRETEPRRAATKTKFT
VDLDSDEDFSDFDEK-TDD---EDFVPSD-A-----SPPKTKTSPKLTNK-DLKPQK---
SAMSDLEAD--D---------AK--DSVPLSSSPPAT---HFPNETEIT-NTVPKKNVTV
KKTA-AKSQ-------------SSTSTTGAKK

PF08070 // ENSGT00390000016222_1_Domain_9 (1773, 1882)

RAAPKG-TK-----KEPALNSGIS-QKP
DPAKTK-IRRKRKPSTSDDSDSNFEKIVSKAVTSKKSRGES-DDFHMD------FDSAVA
PRAKSVR-------AKKPIKYLEESDEDDLF-------

---------MEVSPLQPVNENMQISKTKKNEDAKKGLSIERIYQKKT-QLEHILL-----
---------RP-D-T-YI--GSVELVTQQMWVYDEDIGINYREV

PF02518 // ENSGT00390000016222_1_Domain_0 (105, 255)

TFVPGLYKIFDEILVN
AADNKQRDPNMSCIRVTIDPENNLISIWNNGKGIPVVEHKVEKMYVPALIFGQLLTSSNY
DDDEKKVTGGRNGYGAKLCNIFSTKFTVETASREYKKMFKQ--TWMDNMGRAGEMELKPF
NGEDYTCITFQPDLSKFKMQSLDKDIVALMVRRAYDIAGSTKDVKVFLNGNKLP------
--VKGFRSYVDMYLKDKVDETGNPLKIIHEQVNPRWEVCLTMSEKGFQQISFVNSIATS-
----------------------------------KGGRHVDYVADQIVTKLVDVVKKKNK
GGVAVKAHQVKNHMWIFVNALIENPTFDSQTKENMTL-------------------Q-V-
-K--S-F--G-S--T--C-Q--L-S--E--K------------------FIKA-------
-----------------AIGC-GIV-ES-ILN-WVK-FK-AQV-QLN-KKC-SAV-KHN-
RIK-GIP-KLD-DAND-AGGRNSNE--C-TL-ILT-EGD-SAK-TL-AVS-GL-GVV-GR
-DKY-GVF-PL-RGK-ILN-VR-EAS-HKQ-IME-NAE-INN-IIK-IVG-LQY-KKN-Y
ED-EDS-LKT-LRY-GKI-MI-MTD-QDQ-DGS-HIK-GL-LI-NFI-HH-NWP-SL-LR
H-RF-LEE-FI-TPIV-KVS-KNK-QEMAFYSL---PEF-EEWKSST-------PNHKKW
KVKYYKG------------------LGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAIS
LAF-SKKQIDDRKEWLTHFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNS
DNE

PF00521 // ENSGT00390000016222_1_Domain_6 (964, 1448)

RSIPSMVDGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTII
N--LAQNFVGSNNLNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLARLLFPPKDDHTLK
FLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWSCKIPNFDIREVVNNIRRLMDGEEPLP
MLPSYKNFKGTIEELAPNQYVISGEVAILNSTTIEISELPIRTWTQTYKEQVLEPMLNGT
EKTPPLITDYREYHTD-TTVKFVVKMTEEKLAEAERVGLHKVFKLQTSLTCNSMVLFDHV
GCLKKYDTVLDILRDFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIE
NKPKKELIKVLIQRGY-----D---SDPVKAWKEAQQKVPDE--EENEESDNENEAEKSD
SVRDSGPTFNYLLD-MPLWYLTKEKKDELCKLRNEKEQELETLKRKSPSDLWKEDLAAFI
EELEAVE

ENSGT00390000016222_1_Linker_6_9 (1448, 1773)

TKEKQEEQIGLPGKG---------GKAKGKKT--QM-AEVLPSPCGKRVIPRV
TIEMKAEAEKKIKKKIKNENTEGSP-------PEDGIELEGLKQRLEKK--QKRE---AG
TKTKKQTTLPFKPIKKGKKRNPWSDSESDMSS-NESNFD---VPPRETEPRRAATKTKFT
VDLDSDDDFSDFDEKT-QD---KDFVPS-DG-----SPLKTKASPK-QTT-K----ELKP
QKSA-TSVMDLDA--------DETKDSVPLPPGSPAA---DFSAETEII-NPVSKKKVAV
KKIA-AKSQ-------------SSTATTGAKK

PF08070 // ENSGT00390000016222_1_Domain_9 (1773, 1883)

RAAPKG-SK-----KDPGLNSDVP-QKP
DPPKTK-TRRKRKPSTSDDSDSNFEKMISKTVTNKKSKGES-EDFHLD------LDSAVA
PRAKSGR-------AKKPIKYLEESDEDDLF-------

-------KMTSSHPVNENMQLNKI--K-KNEDTKKRLSIERIYQKKT-QLEHILL-----
---------RP---DTYI--GSVELVTQQMWVYDEDVGINYREV

PF02518 // ENSGT00390000016222_1_Domain_0 (105, 255)

TFVPGLYKIFDEILVN
AADNKQRDPKMSCIRVTIDPENNLISIWNNGKGIPVVEHKVEKVYVPALIFGQLLTSSNY
DDDEKKVTGGRNGYGAKLCNIFSTKFTVETASREYKKKFKQ--TWMDNMGKAGEMELKPF
SGEDYTCITFKPDLSKFKMQSLDKDIVALMVRRAYDIAGSTKDVKVFLNGSTLP------
--VKGFRSYVDMYLKDKVDETGNPLKVIHEQVNHRWEVCLTMSEKGFQQISFVNSIATS-
----------------------------------KGGRHVDYIADQIVTKLVDVVKKKNK
GGVAVKAHQ---------------------------------------------------
------------------------------------------------------------
----------------AT-GC-GIV-ES-ILN-WVK-FK-AQI-QLN-KKC-SAV-KHN-
RIK-GIP-KLD-DAND-AGG-RNS-TDC-TL-ILT-EGD-SAK-TL-AVS-GL-GVV-GR
-DKF-GVF-PL-RGK-ILN-VR-EAS-HKQ-IME-NAE-INN-IIK-IVG-LQY-KKS-Y
ED-EDS-LKT-LRY-GRI-MI-MTD-QDQ-DGS-HIK-GL-LI-NFI-HH-NWP-SL-LR
H-RF-LEE-FIT-PIV-KVS-KNK-QEM-AF-YSL-PEF-EEW-KSS-T-----PNHKKW
KVKYYKG------------------LGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAIS
LAF-SKKQTDDRKEWLTHFMEDRRQRKLLGLPEDYLYGQATTYLTYNDFINKELILFSNS
DNE

PF00521 // ENSGT00390000016222_1_Domain_6 (964, 1448)

RSIPSMVDGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTII
N--LAQNFVGSNNLNLLQPIGQFGTRLHGGKDSASPRYIFTMLXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXDYREYHTD--TVKFVVKMTEEKLAEAERAGLHKVFKLQTSLTCNSMVLFDHV
GCLKKYDTVLDILRDFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIE
NKPKKELIKVLIQRGY-----D---SDPVKAWKEAQQKVPDE--EENEESDDEKETEKSD
SVTDSGPTFNYLLD-MPLWYLTKEKKDELCKLRKEKEQELETLKKKSPSDLWKEDLAVFI
EELEIVE

ENSGT00390000016222_1_Linker_6_9 (1448, 1773)

AKEKQDEQVGLPGK---------GGKGKGKKA--QM-AEVLPSPSGKRVIPQV
TIEMKAEAEKKVKRKIKSENT------EGS-PQEGNVEPESLRQRLEKKQKKEP-----G
TKTKKQTTLPFKPVKKGKKRNPWSDSESDISDNE-NNFDV---PPRELEPRRA-ATSKYT
FDLDSEDDFSDFDEKIED----EDFVPSDA------SPPKAKISPKHTNKEL-----KPQ
KSA-KPDLDADDA----K------DNVLPSSS---APTADLPPETE--MISPVSKKNVTV
------KR--------TAAKGQSSTSTASTKK

PF08070 // ENSGT00390000016222_1_Domain_9 (1773, 1883)

RAAPKRTK------KDPDLASDVSPKKP
GPAKSKNPRKRKP-STSDDSDSNFEKMISKAVTSKKSKGDG-DDFQL------ELDSAVA
PRAKSAR-------AKKPIRYLEESD----EDDLF---

------------------------------------------------------------
-----------------------------MWVYDEDEGLSCRDVTFV

PF02518 // ENSGT00390000016222_1_Domain_0 (108, 253)

PGLYKIFDEILVN
AADNKQRDKNMSCIKITIDPENNTISVWNNGKGIPIVEHKVEKVYVPALIFGQLLTSSNY
DDDEKKVTGGRNGYGAKLCNIFSTKFTVETACREYKKLFKQ--TWTDNMGKAGEMKLKHF
DGEDYTCITFQPDLSKFKMTSLDKDIVALMSRRAYDIAGCAKDVKVFLNGKRLP------
--VKGFRSYVDLYLKDKVDETGNALKVIHEEASSRWEVCLTLSEKGFQQVSFVNSIATT-
----------------------------------KGGRHVDYVADQIVNKLIEVVKKKNK
GGVGVKPFQVKNHMWVFVNSLIENPTFDSQTKENMTLQAKNFG-----------------
---------------STCKL--------------------------SEKFI-----KG--
----------------AV-SC-GIV-ES-ILN-WVK-FK-AQN-QLN-KKC-SAV-KHT-
RIK-GIP-KLD-DAND-AGS-KNS-TDC-TL-ILT-EGD-SAK-TL-AVS-GL-GVV-GR
-DRY-GVF-PL-RGK-MLN-VR-EAS-HKQ-IME-NAE-INN-IIK-IVG-LQY-KKN-Y
DD-QES-LKT-LRY-GKI-MI-MTD-QDQ-DGS-HIK-GL-LI-NFI-HH-NWP-SL-LR
H-RF-LEE-FIT-PII-KVS-KNK-QEF-SF-YSI-PEF-EEW-KNN-T-----ANHKSW
KTKYYKG------------------LGTSTSKEAKEYFADMARHRIGFKYSGPEDDAAIS
LAF-SKKKIEERKEWLTNFMEGRRQRKLHGLPEDFVYGKSTSYLTYNDFIHKELVLFSNS
DNE

PF00521 // ENSGT00390000016222_1_Domain_6 (964, 1336)

RSIPSLVDGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEASLMMTII
N--LAQNFVGSNNLNLLQPVGQFGTRLHGGKDSASPRYIFTMLSPVARLLFPAVDDSVLR
FLYDDNQRVEPEWYIPIIPMVLVNGAEGIGTGWSSRIPNFDIREVVNNIRRMMDGEEPLP
MLPSYKNFKGTIDELGPNQYLINGEVSILDSTTIEISELPVRTWTQTYKEQVLEPMLNGT
EKTPPLITDYREYHTD-TTVKFIVKMSEQKLVEAEAAGLHKVFKLQTNFTCNSMVLFDSV
GFLKKYETPLDILREFFDLRLQYYSLRKEWLNGMLGAESAKLNNQARFILEKIEGIIVIE
NKPKKELIQVLIKRGY-----E---SDPVKAWKESQQKGEEE--EESDNDQ------DNE
SAAASGPDXXXXS-----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------

---------MEVSPLQPVNENMQVNKIKKNEDAKKRLSIERIYQKKT-QLEHILL-----
---------RP-D-T-YI--GSVELVTQQMWVYDEDVGINYREVTFV

PF02518 // ENSGT00390000016222_1_Domain_0 (108, 255)

PGLYKIFDEILVN
AADNKQRDPKMSCIRVTIDPENNLISIWNNGKGIPVVEHKVEKMYVPALIFGQLLTSSNY
DDDEKKVTGGRNGYGAKLCNIFSTKFTVETACREYKKMFKQ--TWMDNMGRAGEMELKPF
NGEDYTCITFQPDLSKFKMQSLDKDIVALMCRRAYDIAGSTKDVKVFLNGNKLP------
--VKGFRSYVDMYLKDKLDETGNPLKVIHEQVNHRWEVCLTMSEKGFQQISFVNSIATS-
----------------------------------KGGRHVDYVADQIVTKLVDVVKKKNK
GGVAVKAHQVKNHMWIFVNALIENPTFDSQTKENMTL-------------------Q-P-
-K--S-F--G-S--T--C-H--L-S--E--K------------------FIKA-------
-----------------AIGC-GIV-ES-ILN-WVK-FK-AQV-QLN-KKC-SAV-KHN-
RIK-GIP-KLD-DAND-AGGRNSTE--C-TL

PF01751 // ENSGT00390000016222_1_Domain_3 (632, 769)

-ILT-EGD-SAK-TL-AVS-GL-GVV-GR
-DRY-GVF-PL-RGK-ILN-VR-EAS-HKQ-IME-NAE-INN-IIK-IVG-LQY-KKN-Y
ED-EDS-LKT-LRY-GKI-MI-MTD-QDQ-DGS-HIK-GL-LI-NFI-

ENSGT00390000016222_1_Linker_3_5 (769, 790)

HH-NWP-SL-LR
H-RF-LEE-

PF16898 // ENSGT00390000016222_1_Domain_5 (790, 962)

FI-TPIV-KVS-KNK-QEMAFYSL---PEF-EEWKSST-------PNHKKW
KVKYYKG------------------LGTSTSKEAKEYFADMKRHRIQFKYCGPEDDAAIS
LAF-SKKQIDDRKEWLTNFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNS
DNERSIPSMVDGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTII
N--LAQNFVGSNNLNLLQPIGQFGTRLHGGKDSASPRYIFTMLSSLARLLFPPKDDHTLK
FLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWSCKIPNFDVREVVNNIRRLMDGEEPLP
MLPSYKNFKGTIEELAPNQYVISGEVAILNSTTIEISELPVRTWTQTYKEQVLEPMLNGT
EKTPPLITDYREYHTD-TTVKFVVKMTEEKLAEAERVGLHKVFKLQTSLTCNSMVLFDHV
GCLKKYDTVLDILRDFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIE
NKPKKELIKVLIQRGY-----D---SDPVKAWKEAQQKVPDE--EENEESDNEKETEKSD
SITDSGPTFNYLLD-MPLWYLTKEKKDELCRLRNEKEQELDTLKRKSPSDLWKEDLAAFI
EELEAVEAKEKQDEQVGLPGKG---------GKAKGKKA--QM-AEVLPSPCGQRVIPLI
TVEMKADAEKKSKRKIKNENTEGSP-------QEDGMELEGLKQRLEKK--QKRE---PG
TKTKKQTTLPFKPIKKGKKRNPWSDSESDRSS-DESNFD---VPPRETEPRRAATKTKFT
VDLDSDEDFSDFDEK-TQD---EDFVPSD-A-----IPPKTKTSLKLNNK-EPKPQK---
SAMSDLEGD--D---------AK--DSVPLSSSPPAT---HFPDETEIT-NPVPKKNVTM
KKTTA-KSQ-------------SSTTTTGAKK

PF08070 // ENSGT00390000016222_1_Domain_9 (1773, 1882)

RAAPKG-TK-----KDPALNSGVS-QKP
DPAKTK-NRRKRKPSTSDDSDSNFEKIVSKAVTSKKSKGES-DDFHMD------FDSALA
PRAKSGR-------AKKPITYLEESDEDDLF-------

----------------MNTQLGKIK---KDEAAKKRLSVERIYQKKT-QLEHILL-----
---------RP---DTYI--GSVELLTQQMWVFDEDAGLNCRDVTFV

PF02518 // ENSGT00390000016222_1_Domain_0 (108, 253)

PGLYKIFDEILVN
AADNKQRDNKMSCIKVTIDPENNTISVWNNGKGIPVVEHKVEKVYVPALIFGQLLTSSNY
DDDEKKVTGGRNGYGAKLCNIFSTKFTVETASREYRKLFKQ--TWTDNMGKAGEMKLKPF
DGEDYTCITFQP

ENSGT00390000016222_1_Linker_0_1 (253, 305)

DLAKFKMTSLDKDIVALMSRRAYDIAGSTKDVKVFLNGKRLP------
--VK

PF00204 // ENSGT00390000016222_1_Domain_1 (305, 590)

GFRGYVDLYVKDKVDETGNPLKVIHEEVNSRWEVCLTMSEKGFQQVSFVNSIATS-
----------------------------------KGGRHVDYVADQIISKLIEVVKKKNK
GGVAVKPHQVKNHMWIFVNSLIENPTFDSQTKENMTLQAKSFG-----------------
---------------SKCQL--------------------------SEKFI-----KA--
----------------AA-SC-GVV-ES-ILN-WVK-FK-AQI-QLN-KKC-SAV-KHN-
RIK-GIP-KLD-DAND-AGS-KNS-TDC-TL-ILT-EGD-SAK-TL-AVS-GL-GVV-GR
-DKY-GVF-PL-RGK-MLN-VR-EAS-HKQ-IME-NAE-INN-IIK-IVG-LQY-KKN-Y
DD-QDS-LKT-LRY-GKI-MI-MTD-QDQ-DGS-HIK-GL-LI-NFI-HH-NWP-SL-LR
H-RF-LEE-FIT-PIV-KVS-RNK-QEM-SF-YSL-PEF-EEW-KNS-T-----GDHKKW
KVKYYKG------------------LGTSTSKEAKEYFSDMTRHRIQFKYSGPEDDAAIS
LAF-SKKQIDDRKEWLTHFMEDRRQRKLHGLPEDYLYGKATNYLTYNDFINKELILFSNS
DNERSIPSMVDGLKPGQRKVLFTCFRRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTII
N--LAQNFVGSNNVNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLARLLFPVKDDNTLK
FLYDDNQRVEPEWYIPIVPMVLVNGAEGIGTGWSCKLPNYDVREVVNNIRRMMDGEEPLP
MLPSYKNFKGTIDELAPNQYVINGEVSILDSTTIEISELPVRTWTQVYKEQVLEPMLNGT
EKTPALIVDYREYHTD-TTVKFIVKMTEQKLAEAEAAGLHKVFKLQTNLTCNSMVLFDHV
GCLKKYDTALDILRDFFELRLKYYGLRKEWLVGMLGAESARLNNQARFILEKIEGKIVIE
NKPKKELIKVLIQRGY-----D---SDPVKAWKEAQQKGSGE--EENEDSENEKETEKSE
STSATGPDFNYLLE-MPLWYLTKEKKDELCRQRDNKTQELETLKRKSPADLWKEDLAAFV
EELEAVETREKQDEQAGLSGKA------TKGGKLKVKKT--QL-AEILPSPHGRRVIPRV
TIEMKAEAEKKIKKKVKSETS------AGS--SPEDKEPLSLKQRLEKKFKSDT-----G
TKGKKQNTLLSKRVKKEKKRNPWSDSESDLSCDD-SDIDVA---PRETKPRRAAAKSKYT
VDLSSDSDSSDSDGKDSTVEEED-FIPTKVT-ASRGAISRTKADPGEPQGKVAKEELEHQ
QTAKAMEIQSSDT----S------DEEGPVSAARDPPTRDPSPVPV--TLSPLPKKSAPA
RGKKTTTA--------TRAKDKGAAAPAATKKA

PF08070 // ENSGT00390000016222_1_Domain_9 (1774, 1835)

AAPKTTKAAAKKASADN-GAVAGPKKA
APAKEKQQRKRKP-ISEDSDDSDFGKKVFKSVATKWIL-------------------SPR
PRGPSGX-------------------------------

---------------------------------------------------HILL-----
---------RP---DTYI--GSVETVTQQMWVFDEELGLNCRDV

PF02518 // ENSGT00390000016222_1_Domain_0 (105, 255)

TFVPGLYKIFDEILVN
AADNKQRDKSMSCIKVTIDPENNTISVWNNGKGIPVVEHKVEKVYVPALIFGQLLTSSNY
DDDEKKVTGGRNGYGAKLCNIFSTKFTVETACREYKKLFKQ--TWTDNMGKAGEMKLKHF
DGEDYTCVTFQPDL

ENSGT00390000016222_1_Linker_0_1 (255, 309)

SKFKMTTLDKDIVALMSRRAYDIAGSTKDVKVFLNGKRLP------
--VKGFRS

PF00204 // ENSGT00390000016222_1_Domain_1 (309, 595)

YVDLYLKDKVDETGNALKVIHEEVNSRWEVCLTLSEKGFQQVSFVNSIATT-
----------------------------------KGGRHVDYVADQIVTKLIDVVKKKNK
NGVGVKPFQVKNHMWIFVNSLIENPTFDSQTKENMTLQAKSFG-----------------
---------------STCKL--------------------------SEKFI-----KG--
----------------AV-GC-GIV-ES-ILN-WVK-FK-AQT-QLN-KKC-SAV-KHT-
KIK-GVP-KLD-DAND-AGN-KNS-IDC-TL-ILT-EGD-SAK-TL-AVS-GL-GVV-GR
-DKY-GVF-PL-RGK-MLN-VR-EAS-HKQ-IME-NAE-INN-IIK-IVG-LQY-KKN-Y
ED-RES-LKS-LRY-GKI-MI-MTD-QDQ-DGS-HIK-GL-LI-NFI-HH-NWP-SL-LR
H-NF-LEE-FIT-PII-KAS-KNK-EEI-AF-YSI-PEF-EEW-KNS-T-----QNYNSW
KIKYYKG------------------LGTSTSKEAKEYFADMARHRIGFKYSGPEDDAAIT
LAF-SKKKVEERKEWLTNFMEDRRQRKLQGLPEDYLYGKDTNYLTYNDFINKELVLFSNS
DNERSIPSLVDGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEASLMMTII
N--LAQNFVGSNNLNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLARLLFPPVDDNVLR
FLYDDNQRVEPEWYMPIIPMVLINGAEGIGTGWSCKIPNFDIRETVNNIRRLLDGNEPLP
MLPSYKNFKGTIDELGPNQYVISGEVSILDSTTIEITELPVRTWTQTYKEQVLEPMLNGT
EKTPSLITDYKEYHTD-TTVKFVVKMSEEKLAEAEAVGLHKVFKLQTNLTCNSMVLFDHV
GFLKKYESPQDILKEFFELRLRYYSLRKEWLIGMLGAESAKLSNQARFILEKIDGKIVIE
NKPKKELIQVLIQRGY-----E---SDPVKAWKELQNKEEEE------GDE-----SDKE
SAAATGPDFNYLLN-MPLWYLTKEKKDELCKQRDNKEKELEDLKCKSPSDLWKEDLAAFV
EELDAVEAKQMQDEMAGITGKPLKAKGGKQGGKQKVTKA--QL-TEVMPSPHGIRVVPQI
TAEMKAEAEKRTKRKIKSEKNESDEKQEGN--SSGDKEPSSLKERLAQKRKAEQ-----G
TK--RQTTLPFKPIKKM-KRNPWSDSDSDSESDD-FEVPS----KRERVVRQAAAKIKPM
VNSDSDADLNSSDEESEYQGNSESNSDSDTN-WKKK-PPKPKAAPKETTEKKAKAPKEK-
PLPDAVPVRAQDV----A------T----ESVSQD-PAAPPVSVPR--S-QAVPKKPAAA
K--KGSTA--------K--DNQPSIVDILTK

PF08070 // ENSGT00390000016222_1_Domain_9 (1772, 1883)

KA-APKPQGAALREELPPSKAA---AKKP
GPQG----RRPQRLSSSSDSDSDFGSKPSKSIAVKKRKRDVDDSYGMDLTA--DRAAAAA
PRSRPGR-------LKKPVQYLES----SDEDDMF---

---------METDPLQPLENK-TVGK--VKKSDNKRLSVERIYQKKT-QLEHILL-----
---------RP---DTYI--GSVEPVTQQMWVFDEDEGLNCRDV

PF02518 // ENSGT00390000016222_1_Domain_0 (105, 255)

TFVPGLYKIFDEILVN
AADNKQRDPTMSCIKITINPESNTVSVWNNGKGIPVVEHKVEKVFVPALIFGQLLTSSNY
DDDQKKVTGGRNGYGAKLCNIFSNKFTVETACREYKKVFKQ--TWTDNMSDAADAKIKPF
DGEDYTCITFQPDLSKFKMQILDKDIVALMSRRAYDVAGSSKGVKVFLNGKRLP------
--ISGFRSYVDLYLKNKLDETGNPLKVMHELVNDRWEICLTMSEKGFQQISFVNSIATT-
----------------------------------KGGRHVDYVADQIIAKLIEVVKKKNK
GGIAVKPFQVKNHMWVFVNSLIENPTFDSQTKENMTLQSKSFG-----------------
---------------SKCTL--------------------------SEKFI-----KG--
----------------AT-NC-GIV-ES-ILN-WVK-FK-AQT-QLN-KKC-SSV-KHT-
KIK-GIP-KLD-DAND-AGI-RNS-LDC-TL-ILT-EGD-SAK-TL-AVS-GL-GVV-GR
-DRY-GVF-PL-RGK-LLN-VR-EAS-HKQ-IME-NAE-INN-IIK-IVG-LQY-KKN-Y
DD-NES-LKT-LRY-GKV-MI-MTD-QDQ-DGS-HIK-GL-LI-NFI-HH-NWP-SL-LK
H-RF-LEE-FIT-PII-KVT-KSK-QEL-SF-YSI-PEF-EEW-KNN-T-----DSHKTW
KIKYYKG------------------LGTSTSKEAKEYFSDMERHRIPFKYEGPIDDAAIT
LAF-SRKKVDDRKEWLTNFMQDRRERRLHGLPEEYLYGKSTKYLTFNDFINKELILFSNS
DNE

PF00521 // ENSGT00390000016222_1_Domain_6 (964, 1448)

RSIPSLVDGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSAYHHGETSLMMTII
N--LAQNFVGSNNVSLLQPIGQFGTRLHGGKDAASPRYIFTMLSTLARLLFPAMDDSVLK
FMYDDNQKVEPEWYIPIIPTVLVNGAEGIGTGWSCKIPNYDTREIVSNIGRLLDGLEPLP
MLPSYKNFKGLIQELGPNQYILNGEVSVLDNTTIEISELPVRTWTQNYKEQVLEPMLNGT
EKTPPLITDYKEYHTD-TTVKFVVKLTEQKLMEAEAAGLHKVFKLQTPLTCNSMVLFDHV
GCLRKYETATDICGIFAFFKLRYFSH---WIFVETFASCLQPYPNCS---------IPI-
TKP--DRIKTVLSYDFSKQAFSRKKVDDRKEWLTNFMQDRRE--R---------RLHGLP
EKKNTGYNTNKFWKMNLIWFVQKLLCXEMSALYSHMNAELQDLKKKSPSDLWKEDLSAFV
EELDRVEAKEREEQSV-TTGKVVK----GKSGRPQVKKM--QL-QEIMPSPHGRRVVPKV
TTAMKAEATKKMKKRIKKMDFEDDGEGDSLNSPEQSPESLTLAERLSKKVKKEPDKGAKA
VKDKKQATLPFKPVKKEAK-STFQDSESESEEEV--------VPRAAQPRRNVAAKVNYM
LSSDEKSDSEFSDFNPKSDSEDESFV-------VAKPAKKPRAAPKKAKKIESPEN-SPQ
KDKAGINVTGSVVFLSSSNNALDEDEDTPIMTSAPSAPAPAPSAKV-SSAKVAEKKPAPK
K--RVQKP--------KTEDRQPSILEALSKPKPSK--SKSTAKKPSSDSEDAAPVPKK-
-AAKATKPRKRK--NSDSDSGSDF------------------------------------
--------------------------------------

---------MEVSPLQPVNENMQVSKTKKNEDAKKRLSIERIYQKKT-QLEHILL-----
---------RP-D-T-YI--GSVESVTQQMWVYDEDIGINYREVTYV

PF02518 // ENSGT00390000016222_1_Domain_0 (108, 254)

PGLYKIFDEILVN
AADNKQRDPKMSCIRITIDPENNLISIWNNGKGIPVVEHKVEKMYVPALIFGQLLTSSNY
DDEEKKVTGGRNGYGAKLCNIFSTKFTVETASREYKKMFKQ--TWMDNMGKAGEMELKPF
SGEDYTCITFHPD

ENSGT00390000016222_1_Linker_0_1 (254, 305)

LSKFKMQSLDKDIVALMVRRAYDIAGSTKDVKVYLNGNRLP------
--VK

PF00204 // ENSGT00390000016222_1_Domain_1 (305, 590)

GFRSYVDLYLKDKVDETGNPLKVIHEQVNHRWEVCLTMSEKGFQQISFVNSIATS-
----------------------------------KGGRHVDYVADQIVTKLVDVVKKKNK
GGVAVKAHQVKNHMWIFVNALIENPTFDSQTKENMTL-------------------Q-V-
-K--S-F--G-S--T--C-Q--L-S--E--K------------------FIKA-------
-----------------AIGC-GIV-ES-ILN-WVK-FK-AQI-QLN-KKC-SAV-KHN-
RIK-GIP-KLD-DAND-AGGRNSTE--C-TL-ILT-EGD-SAK-TL-AVS-GL-GVV-GR
-DKY-GVF-PL-RGK-ILN-VR-EAS-HKQ-IME-NAE-INN-IIK-IVG-LQY-KKN-Y
ED-EDS-LKT-LRY-GKI-MI-MTD-QDQ-DGS-HIK-GL-LI-NFI-HH-NWP-SL-LR
H-RF-LEE-FI-TPIV-KVS-KNK-QEMAFYSL---PEF-EEWKSST-------PNHKKW
KVKYYKG------------------LGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAIS
LAF-SKKQTDDRKEWLTHFMEDRRQRKLLGLPDDYLYGQATTYLTYNDFINKELILFSNS
DNERSIPSMVDGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTII
N--LAQNFVGSNNLNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLARLLFPAKDDHTLK
FLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWSCKIPNFDVREVVNNIRRLMDGEEPLP
MLPSYKNFKGTVEELAPNQYVISGEVAILNSTTIEISELPIRTWTQTYKEQVLEPMLNGT
EKTPPLITDYREYHTD-TTVKFVVKMTEEKLAEAERAGLHKVFKLQTSLTCNSMVLFDHV
GCLKKYDTVLDILRDFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIE
NKPKKELIKVLIQRGY-----D---SDPVKAWKEAQQKVPDE--EENEESDSEKETEKSD
SATDSGPTFNYLLD-MPLWYLTKEKKDELCKLRNEKEQELETLKRKSPSDLWKEDLAAFV
EELEVVEAKEKQDEQIGLPGKG---------GKAKGKKT--QM-VEILPSPSGKRVIPRV
TEEMKAEAEKKIKKKIKSENTEGSP-------QEDGMEMESQKLRLEKK--QKRE---PV
TKTKKQTTLPFKPIKKAKKRNPWSDSESDMSS-NESNFD---VPPREKESRRAAAKTKFT
MDLDSDEDFSDFDEDT-QD----DFVPSNA------SPPKIQTSPKHNNK-EL-----KP
LKSASSEVTELDA--------DDAEDNAPPPPSSPAA---DFPAVTETI-NPVPKKNVTA
KKTA-AKSQ-------------SSTSTTGTKK

PF08070 // ENSGT00390000016222_1_Domain_9 (1773, 1883)

RAAPKK-TK-----KDPDLDSDVS-KKP
NAPKTK-TRRKRKASSSDDSDSNFEKLISKAVTSKKPKEES-DDFHLD------LDSAVG
SRAKSVRT-------KKPIKYLEESDEDDFF-------

---------MEVSPLQPVNENMQMNKIKKNEDAKKRLSIERIYQKKT-QLEHILL-----
---------RP-D-T-YI--GSVELVTQHMWVYDEDVGINYREVTFV

PF02518 // ENSGT00390000016222_1_Domain_0 (108, 253)

PGLYKIFDEILVN
AADNKQRDPKMSCIRVTIDPENNLISIWNNGKGIPVVEHKVEKMYVPALIFGQLLTSSNY
DDDEKKVTGGRNGYGAKLCNIFSTKFTVETASREYKKMFKQ--TWMDNMGRAGEMELKSF
SGEDYTCITFQP

ENSGT00390000016222_1_Linker_0_1 (253, 305)

DLSKFKMQSLDKDIVALMVRRAYDIAGSTKDVKVFLNGNKLP------
--VK

PF00204 // ENSGT00390000016222_1_Domain_1 (305, 590)

GFRSYVDMYLKDKVDETGNPLKVIHEQVNHRWEVCLTMSEKGFQQISFVNSIATS-
----------------------------------KGGRHVDYVADQIVAKLVDVVKKKNK
GGVAVKAHQVKNHMWIFVNALIENPTFDSQTKENMTL-------------------Q-A-
-K--S-F--G-S--T--C-Q--L-S--E--K------------------FIKA-------
-----------------AIGC-GIV-ES-ILN-WVK-FK-AQV-QLN-KKC-SAV-KHN-
RIK-GIP-KLD-DAND-AGSRNSAE--C-TL-ILT-EGD-SAK-TL-AVS-GL-GVV-GR
-DKY-GVF-PL-RGK-ILN-VR-EAS-HKQ-IME-NAE-INN-IIK-IVG-LQY-KKN-Y
ED-EDS-LKT-LRY-GKI-MI-MTD-QDQ-DGS-HIK-GL-LI-NFI-HH-NWP-SL-LR
H-RF-LEE-FI-TPIV-KVS-RNK-QEMAFYSL---PEF-EEWKSST-------PNHKKW
KVKYYKG------------------LGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAIS
LAF-SKKQIDDRKEWLTHFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNS
DNERSIPSMVDGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTII
N--LAQNFVGSNNLNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLARLLFPPKDDHTLR
FLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWSCKIPNFDVREIVNNIRRLMDGEEPLP
MLPSYKNFKGTIEELAPNQYVINGEVAILNSTTIEISELPVRTWTQTYKEQVLEPMLNGT
EKTPPLITDYREYHTD-TTVKFVVKMTEEKLAEAERVGLHKVFKLQTSLTCNSMVLFDHV
GCLKKYDTVLDILKDFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIE
NKPKKELIKVLIQRGY-----D---SDPVKAWKEAQQKVPDE--EENEESDTEKETEKSD
SVTDSGPTFNYLLD-MPLWYLTKEKKDELCRQRNEKEQELETLKRKGPSDLWKEDLAAFI
EELEAVEAKEKQDGAIG---KG---------VKPNGKKT--TN-GLKFAFSTGKNKPPTI
SMDLC-EAPLQIYIYICSENTEGSP-------KEDGTELEDLKQRLEKK--QKRE---PG
TKTKKQTTLPFKPIKKAKKRNPWSDSESDMSS-NESNFD---VPPREIEPRRAATKTKFT
VDLDSDDDFSDFDEK-TQD---DDFVPSY-A-----SPPQTKTSPKPTKK-ELKPQK---
SAMSADLEV--D----------DAKDEAPLSSSPPAA---DFPGETETV-NPVTKKNVTV
KKTA-AKSQ-------------SSTSTTGAKK

PF08070 // ENSGT00390000016222_1_Domain_9 (1773, 1883)

RAAPKG-TK-----KNPALNSDVS-QKP
EPAKTK-TQRKRKPSTSDDSDSNFEKIVSKAVTSKKSKGEN-DDFLLD------LDSSVA
PRAKSSR-------AKKPIKYLEESDEDDLF-------

------------------------------------------------------------
---------------------MEVSPLQQMWVYDEDVGINYREVTFV

PF02518 // ENSGT00390000016222_1_Domain_0 (108, 255)

PGLYKIFDEILVN
AADNKQRDPKMSCIRVTIDPENNLISIWNNGKGIPVVEHKVEKMYVPALIFGQLLTSSNY
DDDEKKVTGGRNGYGAKLCNIFSTKFTVETACREYKKMFKQ--TWMDNMGRAGEMELKPF
NGEDYTCITFQPDLSKFKMQSLDKDIVALMVRRAYDIAGSTKDVKVFLNGNKLP------
--VKGFRSYVDMYLKDKLDETGNPLKVVHEQVNHRWEVCLTMSEKGFQQISFVNSIATS-
----------------------------------KGGRHVDYVADQIVTKLVDVVKKKNK
GGVAVKAHQVKNHMWIFVNALIENPTFDSQTKENMTL-------------------Q-P-
-K--S-F--G-S--T--C-H--L-S--E--K------------------FIKA-------
-----------------AIGC-GIV-ES-ILN-WVK-FK-AQV-QLN-KKC-SAV-KHN-
RIK-GIP-KLD-DAND-AGGRNSTE--C-TL-ILT-EGD-SAK-TL-AVS-GL-GVV-GR
-DRY-GVF-PL-RGK-ILN-VR-EAS-HKQ-IME-NAE-INN-IIK-IVG-LQY-KKN-Y
ED-EDS-LKT-LRY-GKI-M-------DQ-DGS-HIK-GL-LI-NFI-HH-NWP-SL-LR
H-RF-LEE-FI-TPIV-KVS-KNK-QEMAFYSL---PEF-EEWKSST-------PHHKKW
KVKYYKG------------------LGTSTSKEAKEYFADMKRHRIQFKYCGPEDDAAIS
LAF-SKKQIDDRKEWLTNFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNS
DNE

PF00521 // ENSGT00390000016222_1_Domain_6 (964, 1436)

RSIPSMVDGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTII
N--LAQNFVGSNNLNLLQPIGQFGTRLHGGKDSASPRYIFTMLSSLTRLLFPPKDDHTLK
FLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWSCKIPNFDVREVVNNIRRLMDGEEPLP
MLPSYKNFKGTIEELAPNQYVISGEVAILNSTTIEISELPVRTWTQTYKEQVLEPMLNGT
EKTPPLITDYREYHTD-TTVKFVVKMTEEKLAEAERVGLHKVFKLQTSLTCNSMVLFDHV
GCLKKYDTVLDILRDFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIE
NKPKKELIKVLIQRGY-----D---SDPVKAWKEAQQKVPDE--EENEESDNEKESEKSD
SVTDSGPTFNYLLD-MPLWYLTKEKKDELCRLRNEKEQELDTLKRKSPSDLWKED

ENSGT00390000016222_1_Linker_6_9 (1436, 1773)

LATFI
EELEAVEAKEKQDEQVGLPGKG---------GKAKGKKA--QM-AEVLPSPSGQRVIPRI
TIEMKADAEKKSKKKIKNENTEGSP-------QEDGMELEGLKQRLEKK--QKRE---PG
TKTKKQTTLPFKPIKKGKKRNPWSDSESDRSS-DESNFD---VPPRETEPRRAATKTKFT
VDLDSDEDFSDFDEK-TQD---EDFVPSD-A-----SPPKTKTSPKLNNK-EPKPQK---
SATSDLEGD--D---------AK--DSVPLSSSPPAT---HFPDETEIT-NPVPKKNVTV
KKTAA-KSQ-------------SSTTTTGAKK

PF08070 // ENSGT00390000016222_1_Domain_9 (1773, 1882)

RAAPKG-TK-----KDPALNSGVS-QKP
DPVKTK-NRRKRKPSTSDDSDSNFEKIVSKAVTSKKSKGES-DDFHMD------FDSAPA
PRAKSGR-------AKKPITYLEESDEDDLF-------

---------MEVSPLQPVNENMQVNKIKKNEDAKKRLSIERIYQKKT-QLEHILL-----
---------RP-D-T-YI--GSVELVTQQMWVYDEDVGINYREVTFV

PF02518 // ENSGT00390000016222_1_Domain_0 (108, 255)

PGLYKIFDEILVN
AADNKQRDPKMSCIRVTIDPENNLISIWNNGKGIPVVEHKVEKMYVPALIFGQLLTSSNY
DDDEKKVTGGRNGYGAKLCNIFSTKFTVETACREYKKMFKQ--TWMDNMGRAGEMELKPF
NGEDYTCITFQPDLSKFKMQSLDKDIVALMVRRAYDIAGSTKDVKVFLNGNKLP------
--VKGFRSYVDMYLKDKLDETGNPLKVVHEQVNHRWEVCLTMSEKGFQQISFVNSIATS-
----------------------------------KGGRHVDYVADQIVTKLVDVVKKKNK
GGVAVKAHQVKNHMWIFVNALIENPTFDSQTKENMTL-------------------Q-A-
-K--S-F--G-S--T--C-H--L-S--E--K------------------FIKA-------
-----------------AIGC-GIV-ES-ILN-WVK-FK-AQV-QLN-KKC-SAV-KHN-
RIK-GIP-KLD-DAND-AGGRNSTE--C-TL

PF01751 // ENSGT00390000016222_1_Domain_3 (632, 769)

-ILT-EGD-SAK-TL-AVS-GL-GVV-GR
-DRY-GVF-PL-RGK-ILN-VR-EAS-HKQ-IME-NAE-INN-IIK-IVG-LQY-KKN-Y
ED-EDS-LKT-LRY-GKI-MI-MTD-QDQ-DGS-HIK-GL-LI-NFI-

ENSGT00390000016222_1_Linker_3_5 (769, 790)

HH-NWP-SL-LR
H-RF-LEE-

PF16898 // ENSGT00390000016222_1_Domain_5 (790, 962)

FI-TPIV-KVS-KNK-QEMAFYSL---PEF-EEWKSST-------PNHKKW
KVKYYKG------------------LGTSTSKEAKEYFADMKRHRIQFKYCGPEDDAAIS
LAF-SKKQIDDRKEWLTNFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNS
DNERSIPSMVDGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTII
N--LAQNFVGSNNLNLLQPIGQFGTRLHGGKDSASPRYIFTMLSSLTRLLFPPKDDHTLK
FLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWSCKIPNFDVREVVNNIRRLMDGEEPLP
MLPSYKNFKGTIEELAPNQYVISGEVAILNSTTIEISELPIRTWTQTYKEQVLEPMLNGT
EKTPPLITDYREYHTD-TTVKFVVKMAEEKLAEAERAGLHKVFKLQTSLTCNSMVLFDHV
GCLKKYDTVLDILRDFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIE
NRPKKELIKVLIQRGY-----D---SDPVKAWKEAQQKVPDE--EENEESDNEKETEKSD
SVTDSGPTFNYLLD-MPLWYLTKEKKDELCRLRNEKEQELDMLKRKSPSDLWKEDLAAFI
EELEAVEAKEKQDEQVGLPGKG---------GKAKGKKA--QM-AEVLPSPSGQRVIPRI
TIEMKADAEKKSKKKIKNENTEGSP-------QEDGMELEGLKQRLEKK--QKRE---PG
TKTKKQTTLPFKPIKKGKKRNPWSDSESDRSS-DESNFD---VPPRETEPRRAATKTKFT
VDLDSDEDFSDFDEK-TQD---EDFVPSD-A-----SPPKTKTSPKLNNK-EPKPQK---
SAMPDLEGD--D---------AK--DSVPLSSSPPAT---HFPDETEIT-NPVPKKNVTV
KKTAA-KSQ-------------SSTTTTGAKK

PF08070 // ENSGT00390000016222_1_Domain_9 (1773, 1882)

RAAPKG-TK-----KDPALNSGVS-QKP
DPAKTK-NRRKRKPSISDDSDSNFEKIVSKAVTSKKSRGES-DDFHMD------FDSALA
PRAKSGR-------AKKPITYLEESDEDDLF-------

------------------------------------------------------------
------------------------------------------------------------
--------------------

PF02518 // ENSGT00390000016222_1_Domain_0 (141, 255)

ENNTISIWNNGKGIPVVEHKVEKVYVPALIFGQLLTSSNY
DDDEKKVTGGRNGYGAKLCNIFSTKFTVETACKEYKKLFKQ--TWMDNMGKAGEMILKPF
SGEDYTCITFQPDL

ENSGT00390000016222_1_Linker_0_2 (255, 309)

SKFKMTNLDKDIVALMSRRAYDIAGSTKDVKVFLNGSRLP------
--VKGFRS

PF00204 // ENSGT00390000016222_1_Domain_2 (309, 360)

YVDLYVKDKLDETGNPLKIIHEEVNNRWEVCLTMSEKGFQQISFVNSIATSK
XXXXXXXXXXXX-----------------------------------XXXXX--------
------------------------------------------------------------
---------X-----XXXXX----------------------------------------
------XXXXXXXXXXXAIGC-GIV-ES-ILN-WVK-FK-AQV-QLN-KKC-SAV-KHN-
RIK-GIP-KLD-DAND-AGSKNST--DC-TL-ILT-EGD-SAK-TL-AVS-GL-GVV-GR
-DKY-GVF-PL-RGK-ILN-VR-EAS-HKQ-IME-NAE-INN-IIK-IVG-LQY-KKN-Y
ED-ADS-LKS-LRY-GKI-MI-MTDQXXXXXXX-XXXXXX--X-XXX-XX-XXX-XX-XX
X-XX-XXX-XXX-XXX-XXX-XXX-XXXXXXXXXX-XXX-XXXXXXX-X-----XXXXXX
XXXXXXX-----------XX-----XXXXXXXXXXXXXXX---XX-----XXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDYLYGKATKHLTYNDFINKELILFSNS
DNE

PF00521 // ENSGT00390000016222_1_Domain_6 (964, 1451)

RSIPSMVDGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTII
N--LAQNFVGSNNLNLLQPIGQFGTRLHGGKDSASPRYIFTMLXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
NKPKKELIKVLIQRGY-----D---SDPVKAWKEAQQKSPEDNEEENEESENEKETEKSG
SATDSGPTFNYLLD-MPLWYLTKEKKDELCRQRAEKXXXXXXXXXXXXXXXXXXXXXXXX
XXXXVVEAKEKRDEQVGVVGKG------KAGSKPKAKKG--QL-AEILPSPCGRRVIPRV
TVEMKAEAEKKIRKKIKXESIEESS-------QDDSIEPETLKQRLNKKVKTEPXXXXXX
XXXXXXXXXXXXXXXXXXXXXX---------XXXXXXXXXXXXXXXXXXXXXXXXNTKYT
VDLDSDSDISDSKEEFQ----DEDFIPSDESSSQVKSAPLEPEN---TKDMA--------
-------------------------------LASSSSSAFDFPAEIETT-DPAPQKSAAG
KKTAAK------------------------------------------------------
------------------------------------------------------------
--------------------------------------

---------MEVSPLQPVNENMQVNKIKKNEDAKKRLSIERIYQKKT-QLEHILL-----
---------RP-D-T-YI--GSVELVTQQMWVYDEDVGINYREVTFV

PF02518 // ENSGT00390000016222_1_Domain_0 (108, 255)

PGLYKIFDEILVN
AADNKQRDPKMSCIRVTIDPENNLISIWNNGKGIPVVEHKVEKMYVPALIFGQLLTSSNY
DDDEKKVTGGRNGYGAKLCNIFSTKFTVETASREYKKMFKQ--TWMDNMGRAGEMELKPF
SGEDYTCITFQPDLSKFKMQSLDKDIVALMVRRAYDIAGSTKDVKVFLNGNKLP------
--VKGFRSYVDMYLKDKLDETGNPLKVIHEQVNHRWEVCLTMSEKGFQQISFVNSIATS-
----------------------------------KGGRHVDYVADQIVTKLVDVVKKKNK
GGVAVKAHQVKNHMWIFVNALIENPTFDSQTKENMTL-------------------Q-P-
-K--S-F--G-S--T--C-Q--L-S--E--K------------------FIKA-------
-----------------AIGC-GIV-ES-ILN-WVK-FK-AQV-QLN-KKC-SAV-KHN-
RIK-GIP-KLD-DAND-AGGRNSTD--C-TL

PF01751 // ENSGT00390000016222_1_Domain_3 (632, 769)

-ILT-EGD-SAK-TL-AVS-GL-GVV-GR
-DKY-GVF-PL-RGK-MLN-VR-EAS-HKQ-IME-NAE-INN-IIK-IVG-LQY-KKN-Y
ED-EDS-LKT-LRY-GKI-MI-MTD-QDQ-DGS-HIK-GL-LI-NFI-

ENSGT00390000016222_1_Linker_3_4 (769, 790)

HH-NWP-SL-LR
H-RF-LEE-

PF16898 // ENSGT00390000016222_1_Domain_4 (790, 850)

FI-TPIV-KVS-KNK-QEMAFYSL---PEF-EEWKSST-------PNYKKW
KVKYYKGLT

ENSGT00390000016222_1_Linker_4_5 (850, 865)

SYFIIHPVQDYMREL

PF16898 // ENSGT00390000016222_1_Domain_5 (865, 962)

GLGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAIS
LAF-SKKQIDDRKEWLTNFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNS
DNERSIPSMVDGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTII
N--LAQNFVGSNNLNLLQPIGQFGTRLHGGKDSASPRYIFTMLSSLARLLFPPKDDHTLK
FLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWSCKIPNFDVREVVNNIRRLMDGEEPLP
MLPSYKNFKGTIEELAPNQYVISGEVAILNSTTIEISELPIRTWTQTYKEQVLEPMLNGT
EKTPPLITDYREYHTD-TTVKFVVKMTEEKLAEAERVGLHKVFKLQTSLTCNSMVLFDHV
GCLKKYDTVLDILRDFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIE
NKPKKELIKVLIQRGY-----D---SDPVKAWKEAQQKVPDE--EENEESDNEKETEKSD
SVTDSGPTFNYLLD-MPLWYLTKEKKDELCRLRNEKEQELDTLKRKSPSDLWKEDLATFI
EELEAVEAKEKQDEQVGLPGKA---------GKAKGKKT--QM-AEVLPSPRGQRVIPRI
TIEMKAEAEKKNKKKIKNENTEGSP-------QEDGMELEGLKQRLEKK--QKRE---PG
TRTKKQTTLPFKPIKKGKKRNPWSDSESDRSS-DESNFD---VPPRETEPRRAATKTKFT
VDLDSDEDFSDFDEK-TDD---EDFVPSD-A-----SPPKTKTSPKLTNK-DLKPQK---
SAMSDLEAD--D---------AK--DSVPLSSSPPAT---HFPNETEIT-NTVPKKNVTV
KKTA-AKSQ-------------SSTSTTGAKK

PF08070 // ENSGT00390000016222_1_Domain_9 (1773, 1882)

RAAPKG-TK-----KEPALNSGIS-QKP
DPAKTK-IRRKRKPSTSDDSDSNFEKIVSKAVTSKKSRGES-DDFHMD------FDSAVA
PRAKSVR-------AKKPIKYLEESDEDDLF-------

MVLVVKYYRLHWLLWSPVNENMQISKTKKNEDAKKRLSIERIYQKKT-QLEHILL-----
---------RP-D-T-YI--GSVELVTQQMWVYDEDIGMNYREVTFV

PF02518 // ENSGT00390000016222_1_Domain_0 (108, 253)

PGLYKIFDEILVN
AADNKQRDPKMSCIRVTIDPENNLISIWNNGKGIPVVEHKVEKMYVPALIFGQLLTSSNY
DDDEKKVTGGRNGYGAKLCNIFSTKFTVETASREYKKMFKQ--TWMDNMGRAGEMELRPF
NGEDYTCITFQPDLSKFKMQSLDKDIVALMVRRAYDIAGSTKDVKVFLNGNKLP------
--VKGFRSYVDMYLKDKVDETGNPLKIIHEQVNPRWEVCLTMSEKGFQQISFVNSIATS-
----------------------------------KGGRHVDYIADQIVTKLVDVVKKKNK
GGVAVKAHQVKNHMWIFVNALIENPTFDSQTKENMTL-------------------Q-V-
-K--S-F--G-S--T--C-Q--L-S--E--K------------------FIKA-------
-----------------ATGC-GIV-ES-ILN-WVK-FK-AQI-QLN-KKC-SAV-KHN-
RIK-GIP-KLD-DAND-AGGRNSNE--C-

PF01751 // ENSGT00390000016222_1_Domain_3 (630, 781)

TL-ILT-EGD-SAK-TL-AVS-GL-GVV-GR
-DKY-GVF-PL-RGK-ILN-VR-EAS-HKQ-IME-NAE-INN-IIK-IVG-LQY-KKN-Y
DD-EDS-LKT-LRY-GKI-MI-MTD-QDQ-DGS-HIK-GL-LI-NFI-HH-NWP-SL-LR
H-RF-LEE-FI-TPIV-KVS-KNK-QEMAFYSL---PEF-EEWKSST-------PNHKKW
KVKYYKG------------------LGTSTSKEAKEYFANMKRHRIQFKYSGPEDDAAIS
LAF-SKKQIDDRKEWLTHFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNS
DNE

PF00521 // ENSGT00390000016222_1_Domain_6 (964, 1436)

RSIPSMVDGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTII
N--LAQNFVGSNNLNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLARLLFPPKDDQTLK
FLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWSCKIPNFDIREVVNNIRRLMDGEEPLP
MLPSYKNFRGTIEELAPNQYVISGEVAILNSTTIEISELPVRTWTQTYKEQVLEPMLNGT
EKTPPLITDYREYHTD-TTVKFVVKMTEEKLAEAERVGLHKVFKLQTSLTCNSMVLFDHV
GCLKKYDTVLDILRDFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIE
NKPKKELIKVLIQRGY-----D---SDPVKAWKEAQQKVPDE--EENEESDNENEAEKSD
SVRDSGPTFNYLLD-MPLWYLTKEKKDELCKLRNEKEQELETLKRKSPTDLWKED

ENSGT00390000016222_1_Linker_6_9 (1436, 1773)

LATFV
EELEAVETKEKQEEQIGLPGKG---------GKGKGKKT--QM-AEVLPSPCGKRVIPRV
TIEMKAEAEKKNKKKIKNENTEGSP-------QEESIEIEGLKQRLEKK--QKRE---PG
TKTKKQTTLPFKPIKKGKKRNPWSDSESDMSS-NESNFD---VPPREVEPRRAATKTKFT
VDLDLDDSFSDFEERI-QD---EDSVPS-DV-----SPHKTKASPK-RTA-K----ELKP
QKSA-PPVMDLDA--------DDAKDSVPLSPGST-A---DFLAETEIV-NPLPKKKVDV
KKIA-PKSQ-------------SSTSTTGAKK

PF08070 // ENSGT00390000016222_1_Domain_9 (1773, 1883)

RAAPKG-TK-----KDPGLNSDVS-QKP
DPPKTK-NHRKRKPSTSDDSDSNFEKMISKAATNKKSKGES-EDFHLD------LDSGVA
PRAKSGR-------ARKPIKYLEESDEDDLF-------

---------MEVSPLQPVNENMQVNKIKKNEDAKKRLSIERIYQKKT-QLEHILL-----
---------RP-D-T-YI--GSVELVTQQMWVYDEDVGINYREVTFV

PF02518 // ENSGT00390000016222_1_Domain_0 (108, 255)

PGLYKIFDEILVN
AADNKQRDPKMSCIRVTIDPENNLISIWNNGKGIPVVEHKVEKMYVPALIFGQLLTSSNY
DDDEKKVTGGRNGYGAKLCNIFSTKFTVETASREYKKMFKQ--TWMDNMGRAGEMELKPF
SGEDYTCITFQPDLSKFKMQSLDKDIVAIMVRRAYDIAGSTKDVKVFLNGNKLP------
--VKGFRSYVDMYLKDKLDETGNPLKVIHEQVNHRWEVCLTMSEKGFQQISFVNSIATS-
----------------------------------KGGRHVDYVADQIVTKLVDVVKKKNK
GGVAVKAHQVKNHMWIFVNALIENPTFDSQTKENMTL-------------------Q-P-
-K--S-F--G-S--T--C-Q--L-S--E--K------------------FIKA-------
-----------------AIGC-GIV-ES-ILN-WVK-FK-AQV-QLN-KKC-SAV-KHN-
RIK-GIP-KLD-DAND-AGGRNSTD--C-TL

PF01751 // ENSGT00390000016222_1_Domain_3 (632, 769)

-ILT-EGD-SAK-TL-AVS-GL-GVV-GR
-DKY-GVF-PL-RGK-MLN-VR-EAS-HKQ-IME-NAE-INN-IIK-IVG-LQY-KKN-Y
ED-EDS-LKT-LRY-GKI-MI-MTD-QDQ-DGS-HIK-GL-LI-NFI-HH-NWP-SL-LR
H-RF-LEE-FI-TPIV-KVS-KNK-QEMAFYSL---PEF-EEWKSST-------PNYKKW
KVKYYKG------------------LGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAIS
LAF-SKKQIDDRKEWLTNFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNS
DNE

PF00521 // ENSGT00390000016222_1_Domain_6 (964, 1436)

RSIPSMVDGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTII
N--LAQNFVGSNNLNLLQPIGQFGTRLHGGKDSASPRYIFTMLSSLARLLFPPKDDHTLK
FLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWSCKIPNFDVREVVNNIRRLMDGEEPLP
MLPSYKNFKGTIEELAPNQYVISGEVAILNSTTIEISELPIRTWTQTYKEQVLEPMLNGT
EKTPPLITDYREYHTD-TTVKFVVKMTEEKLAEAERVGLHKVFKLQTSLTCNSMVLFDHV
GCLKKYDTVLDILRDFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIE
NKPKKELIKVLIQRGY-----D---SDPVKAWKEAQQKVPDE--EENEESDNEKETEKSD
SVTDSGPTFNYLLD-MPLWYLTKEKKDELCRLRNEKEQELDTLKRKSPSDLWKED

ENSGT00390000016222_1_Linker_6_9 (1436, 1773)

LATFI
EELEAVEAKEKQDEQVGLPGKA---------GKAKGKKT--QM-AEVLPSPRGQRVIPRI
TIEMKAEAEKKNKKKIKNENTEGSP-------QEDGMELEGLKQRLEKK--QKRE---PG
TKTKKQTTLPFKPIKKGKKRNPWSDSESDRSS-DESNFD---VPPRETEPRRAATKTKFT
VDLDSDEDFSDFDEK-TDD---EDFVPSD-A-----SPPKTKTSPKLTNK-DLKPQK---
SAMSDLEAD--D---------AK--DSVPLSSSPPAT---HFPNETEIT-NTVPKKNVTV
KKTA-AKSQ-------------SSTSTTGAKK

PF08070 // ENSGT00390000016222_1_Domain_9 (1773, 1882)

RAAPKG-TK-----KEPALNSGIS-QKP
DPAKTK-IRRKRKPSTSDDSDSNFEKIVSKAVTSKKSRGES-DDFHMD------FDSAVA
PRAKSVR-------AKKPIKYLEESDEDDLF-------

---------MEVSPLQPLSENMQMNK-KKNEDAKKRLSIERIYQKKT-QLEHILL-----
---------RP-D-T-YI--GSVELVTQHLWVYDEEIGINYREVTFV

PF02518 // ENSGT00390000016222_1_Domain_0 (108, 255)

PGLYKIFDEILVN
AADNKQRDPKMSCIRVTIDPENNLISIWNNGKGIPVVEHKVEKMYVPALIFGHLLTSSNY
DDDEKKVTGGRNGYGAKLCNIFSTKFTVETASREYKKMFKQ--TWMNNMGKAGEMELKPF
SGEDYTCITFQPDLSKFKMQNLDKDIVALMVRRAYDIAGSTKDVKVFLNGNKLP------
--VKGFRSYVDMYLKDKLDETGNPLKVIHEQVNHRWEVCLTMSEKGFQQISFVNSIATS-
----------------------------------KGGRHVDYVADQIVSKLVDVVKKKNK
GGVAVKAHQVKNHMWIFVNALIENPTFDSQTKENMTL-------------------Q-A-
-K--S-F--G-S--T--C-Q--L-S--E--K------------------FIKA-------
-----------------ATGC-GIV-ES-ILN-WVK-FK-AQV-QLN-KKC-SAV-KHN-
RIK-GIP-KLD-DAND-AGTLSMLSILC-MD-IFS-NFL-LLT-TS--------------
-----VIF----NLE-ILD-V--SHQ-NLS-IME-NAE-INN-IIK-IVG-LQY-KKN-Y
ED-EDS-LKT-LRY-GKI-MI-MTD-QDQ-DGS-HIK-GL-LI-NFI-HH-NWP-SL-LR
H-RF-LEE-

PF16898 // ENSGT00390000016222_1_Domain_5 (790, 962)

FI-TPIV-KVS-KNK-QEMAFYSL---PEF-EEWKSST-------PNHKKW
KVKYYKG------------------LGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAIS
LAF-SKKQIDDRKEWLTNFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNS
DNERSIPSMVDGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTII
N--LAQNFVGSNNLNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLARLLFPPKDDHTLK
FLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWSCKIPNFDVREVVNNIRRLMDGEEPLP
MLPSYKNFKGTIEELASNQYVISGEVAILNSTTIEISELPIRTWTQTYKEQVLEPMLNGT
EKTPPLITDYREYHTD-TTVKFVVKMTEEKLAEAERVGLHKVFKLQTSLTCNSMVLFDHV
GCLKKYDTVLDILRDFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIVIE
NKPKKELIKVLIQRGY-----D---SDPVKAWKEAQQKVPDE--EENEESDN----EKNE
SVPDSGPSFNYLLD-MPLWYLTKEKKDELCKQRNEKEQELDTLKKKSPSDLWKEDLAAFI
EELEVVEAKEKQDEQIGLPGKG---------GKAKGKKT--QM-MEVLPSPQGKRVIPQV
TIEMKAEAEKKIKRKIKSENTEA---------KEDGMEIESLKERLEKK--QKRE---PG
AKAKKQTTLPFKPVKKGKKKNPWSDSESDMSS-TESNFD---VPPREIEPRRAATKSKFT
VDLDSDEDFSDFDEKI-ED---EDFVPSD-A-----SPPKTKAPPKHTEK-ELKPQKSAT
------SVV--NL--------DDAEENVAPSSSLPS---ADLPAKIEILT-QPSKKNVTV
KKTT-TKSQ-------------SSTSVAGTKK

PF08070 // ENSGT00390000016222_1_Domain_9 (1773, 1882)

RAAPKK-TK-----TDPALNSDNS-QKP
DPAKNK-TRRKRKPSTSDDSDSNFEKIISKAATSKKPKGET-DEFLLD------FDSAVA
PRAKSVR-------AKKPIKYLEESDEDDLF-------

---------MEVSPLQPLNENMEMNKMKKNEDAKKRLSIERIYQKKT-QLEHILL-----
---------RP---DTYI--GSVELVTQQMWVYDEDIGINYREVTFV

PF02518 // ENSGT00390000016222_1_Domain_0 (108, 294)

PGLYKIFDEILVN
AADNKQRDPKMSCIRVTIDPENNLISIWNNGKGIPVVEHKVEKMYVPALIFGQLLTSSNY
DDDEKKV-----------------------------------------------------
-----------------------------------------------------T------
--VKGFRSYVDMYLKDKLDETGNPLKVIHEQVNHRWEVCLTMSEKGFQQISFVNSIATS-
----------------------------------KGGRHVDYVADQIVTKLVDVVKKKNK
GGVAVKAHQVKNHMWIFVNALIENPTFDSQTKENMTLQAKS-------------------
------F--G-----STCQL--------------------------SEKFIKA-------
-----------------AIGC-GIV-ES-ILN-WVK-FK-AQV-QLN-KKC-SAV-KHN-
RIK-GIP-KLD-DAND-AGSRNSTE--C-TL

PF01751 // ENSGT00390000016222_1_Domain_3 (632, 769)

-ILT-EGD-SAK-TL-AVS-GL-GVV-GR
-DRY-GVF-PL-RGK-ILN-VR-EAS-HKQ-IME-NAE-INN-IIK-IVG-LQY-KKN-Y
ED-EDS-LKT-LRY-GKI-MI-MTD-QDQ-DGS-HIK-GL-LI-NFI-HH-NWP-SL-LR
H-RF-LEE-FI-TPIV-KVS-KNK-QEMAFYSL---PEF-EEWKSST-------PNHKKW
KVKYYKG------------------LGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAIS
LAF-SKKQIDDRKDWLTHFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNS
DNE

PF00521 // ENSGT00390000016222_1_Domain_6 (964, 1436)

RSIPSMVDGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTII
N--LAQNFVGSNNLNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLARLLFPPKDDHTLK
FLYDDNQRVEPEWYIPIIPMVLVNGAEGIGTGWSCKIPNFDVREVVNNIRRLMDGEEPLP
MLPSYKNFRGTIEELAPNQYVINGEVAILNSTTIEISELPIRTWTQTYKEQVLEPMLNGT
EKTPPLITDYREYHTD-TTVKFVVKMTEEKLAEAERAGLHKVFKLQTSLTCNSMVLFDHV
GCLKKYDTALDILRDFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIE
NKPKKELIKVLIQRGY-----D---SDPVKAWKEAQQKVPDE--EDNEESDSEKETAKGD
SAADTGPTFAYLLD-MPLWYLTKEKKDELCKQRSEKEQELHTLKKKSPSDLWKED

ENSGT00390000016222_1_Linker_6_9 (1436, 1773)

LAAFV
EELEAVEAKEKQDEQVGLPGKG---------GKPKGKKA--QM-AEVLPSQQGTRVIPRV
TVEMKAEAEKKIKKKIKSENTEGTP-------AEDSVELESLKQRLEKK--QKRE---PG
ARAKKQTTLPFKPIRKGKKRNPWSDSESDMSS-TESNFD---VPPREIEPRRAAAKTKFT
MDLDSDEDFSDSDEKAEE----DDFVPSD-A-----SPPKAKTPPKFTKR-EPKPQK-IT
VSVTG-----LEA--------AGAEDREP-----PA----DLPAQPEAT-KPPPERSATM
KKTTAKGQ--------------SSASTAGTKK

PF08070 // ENSGT00390000016222_1_Domain_9 (1773, 1882)

RAAPKG-AK-----KDPALNSEAS-AKP
DPAKTK-YRRKRKPSTSDDSDSNFEKIISKGATSKKSKAES-DDFQMA------LDSSVT
PRAKSGR-------TKKPIKYLEDSDDDDLF-------

---------MEVSPLQPVNEHMQMNKIKKNEDAKKRLSIERIYQKKT-QLEHILL-----
---------RP---DTYI--GSVELLTQQMWVYDEDIGINYREITFV

PF02518 // ENSGT00390000016222_1_Domain_0 (108, 255)

PGLYKIFDEILVN
AADNKQRDPKMSCIRVTIDPENNLISVWNNGKGIPVVEHKVEKVYVPALIFGQLLTSSNY
DDDERKVTGGRNGYGAKLCNIFSTRFTVETASKDYKKMFKQ--TWMDNMGRAGEMELKPF
SGEDYTCITFQPDL

ENSGT00390000016222_1_Linker_0_1 (255, 305)

SKFKMERLDKDIVALMVRRAYDIAGSTKDVKVFLNGNKLP------
--VT

PF00204 // ENSGT00390000016222_1_Domain_1 (305, 590)

GFRSYVDMYLKDKLDETGNPLKVIHEQVNQRWEVCLTMSEKGFQQISFVNSIATS-
----------------------------------KGGRHVDYVADQIVTKLMDVVKKKNK
GGIAVKAHQVKNHMWIFVNALIENPTFDSQTKENMTLQVKS-------------------
------F--G-----STCQL--------------------------SEKFIKA-------
-----------------AIGC-GIV-ES-ILN-WVK-FK-AQV-QLN-K

ENSGT00390000016222_1_Linker_1_3 (590, 632)

KC-SAV-KHN-
KIK-GIP-KLD-DAND-AGSRNSTE--C-TL

PF01751 // ENSGT00390000016222_1_Domain_3 (632, 769)

-ILT-EGD-SAK-TL-AVS-GL-GVV-GR
-DKY-GVF-PL-RGK-MLN-VR-EAS-HKQ-IME-NAE-INN-IIK-IVG-LQY-KKN-Y
AD-EDS-LKT-LRY-GKI-MI-MTD-QDQ-DGS-HIK-GL-LI-NFI-HH-NWP-SL-LQ
H-RF-LEE-FI-TPIV-KVS-KNK-QELAFYSL---PEF-EEWKSST-------PNHKKW
KVKYYKG------------------LGTSTSKEAKEYFADMKKHRIQFKYSGPEDDAAIS
LAF-SKKQIDDRKEWLTHFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNS
DNERSIPSMVDGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTII
N--LAQNFVGSNNVNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLARLLFPPKDDHTLN
FLYDDNQRVEPEWYIPIIPMVLVNGAEGIGTGWSCKIPNFDVREIVNNIRRLMDGEEPLP
MLPSYKNFKGTIEELASNQYVINGEVAILNSTTIEISELPIRTWTQTYKEQVLEPMLNGT
EKTPPLITDYREYHTD-TTVKFIVKMTEEKLSEVERAGLHKVFKLQTSLTCNSMVLFDHV
GCLKKYDTVLDILRDFFELRLKYYGLRKEWLLGMLGAESSKLNNQARFILEKIDGKIIIE
NKPKKELIKVLIQRGY-----D---SDPVKAWKEAQQKVPEE--EENEESDSEKEAAKGD
PAADSGPTFNYLLD-MPLWYLTKEKKDELCRQRDEKEQELDTLKKKSPSDLWREDLAAFI
EELEVVEAKEKQDEQVGLVGKG---------GKGKGKKA--PA-AETLPSLQGIRVVPRV
TTEMKAEAEKKIRKKLKTENTEGAP-------AEDSVEMDSLKLKLEKK--QKTE---PG
TKAKKQTTLPFKPVKKGKKRNPWSDSDSEMSSTSEGHFD---LPSREVKQRRAAANTRFT
MDLDSDEDFSDFDKK-ND----DDFVPSD-A-----SPLKAKSLPQLTKK-EPKPQKSIA
-SVAG-----PEP--------EDSEDGGLPASGPSD----DAPARLPA-------SSVTT
KKTATKGQSSSPTTGAKKRAVPKRAPTAGDKKR

PF08070 // ENSGT00390000016222_1_Domain_9 (1774, 1882)

AVPKR-AK-----KDPALDPEAP-EKP
DPKTKS-RCKRRPSSSSDDSDSSLAKMAPKGARNKRPKAEG-DDFQLD------LQSAVA
PRAKSAR-------ARKPIKYLEESDEDELF-------

---------MEVSPLQPVNENMQVNKIKKNEDAKKRLSIERIYQKKT-QLEHILL-----
---------RP-D-T-YI--GSVELVTQQMWVYDEDVGINYREVTFV

PF02518 // ENSGT00390000016222_1_Domain_0 (108, 255)

PGLYKIFDEILVN
AADNKQRDPKMSCIRVTIDPENNLISIWNNGKGIPVVEHKVEKMYVPALIFGQLLTSSNY
DDDEKKVTGGRNGYGAKLCNIFSTKFTVETASREYKKMFKQ--TWMDNMGRAGEMELKPF
SGEDYTCITFQPDLSKFKMQSLDKDIVALMVRRAYDIAGSTKDVKVFLNGNKLP------
--VKGFRSYVDMYLKDKLDETGNPLKVIHEQVNHRWEVCLTMSEKGFQQISFVNSIATS-
----------------------------------KGGRHVDYVADQIVTKLVDVVKKKNK
GGVAVKAHQVKNHMWIFVNALIENPTFDSQTKENMTL-------------------Q-P-
-K--S-F--G-S--T--C-Q--L-S--E--K------------------FIKA-------
-----------------AIGC-GIV-ES-ILN-WVK-FK-AQV-QLN-KKC-SAV-KHN-
RIK-GIP-KLD-DAND-AGGRNSAD--C-TL

PF01751 // ENSGT00390000016222_1_Domain_3 (632, 769)

-ILT-EGD-SAK-TL-AVS-GL-GVV-GR
-DKY-GVF-PL-RGK-ILN-VR-EAS-HKQ-IME-NAE-INN-IIK-IVG-LQY-KKN-Y
ED-EDS-LKT-LRY-GKI-MI-MTD-QDQ-DGS-HIK-GL-LI-NFI-HH-NWP-SL-LR
H-RF-LEE-FI-TPIV-KVS-KNK-QEMAFYSL---PEF-EEWKSST-------PNHKKW
KVKYYKG------------------LGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAIS
LAF-SKKQIDDRKEWLTNFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNS
DNE

PF00521 // ENSGT00390000016222_1_Domain_6 (964, 1436)

RSIPSMVDGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTII
N--LAQNFVGSNNLNLLQPIGQFGTRLHGGKDSASPRYIFTMLSSLARLLFPPKDDHTLR
FLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWSCKIPNFDVREVVNNIRRLMDGEEPLP
MLPSYKNFKGTIEELAPNQYVISGEVAILNSTTIEISELPIRTWTQTYKEQVLEPMLNGT
EKTPPLITDYREYHTD-TTVKFVVKMTEEKLAEAERVGLHKVFKLQTSLTCNSMVLFDHV
GCLKKYDTVLDILRDFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIE
NKPKKELIKVLIQRGY-----D---SDPVKAWKEAQQKVPDE--EENEESDNEKETEKSN
SVTDSGPTFNYLLD-MPLWYLTKEKKDELCRLRNEKEQELDTLKRKSPSDLWKED

ENSGT00390000016222_1_Linker_6_9 (1436, 1773)

LATFI
EELEAVEAKEKQDEQIGLPGKG---------GKAKGKKT--QM-AEVLPSPRGQRVIPRI
TIEMKAEAEKKNKKKIKNENTEGSP-------QEDGMELEGLKQRLEKK--QKRE---PG
TKTKKQTTLPFKPIKKGKKRNPWSDSESDRSS-DESNFD---VPPRETEPRRAATKTKFT
VDLDSDEDFSDFDEK-TDD---EDFVPSD-A-----SPPKTKTSPKLTNK-DLKPQK---
SAMSDLEVD--D---------AK--DSVPLSSSPPAT---HFPNETEIT-NTVPKKNVTV
KKTA-AKSQ-------------SSTSTTGAKK

PF08070 // ENSGT00390000016222_1_Domain_9 (1773, 1882)

RAAPKG-TK-----REPALNSGVS-QKP
DPAKTK-IRRKRKPSTSDDSDSNFEKIVSKAVTSKKSRGES-DDFHMD------FDSAVA
PRAKSVR-------AKKPIKYLEESDEDDLF-------

---------MEVSPLQPVNENMKIDKIKKNEDAKKRLSIERIYQKKT-QLEHILL-----
---------RP-D-T-YI--GSVELVTQQMWVYDEDVGINYREVTFV

PF02518 // ENSGT00390000016222_1_Domain_0 (108, 255)

PGLYKIFDEILVN
AADNKQRDPKMSCIRVTIDPENNLISIWNNGKGIPVVEHKVEKMYVPALIFGHLLTSSNY
DDDEKKVTGGRNGYGAKLCNIFSTKFTVETASREYKKMFKQ--TWRDNMGRTGEMELKPF
NGEDYTCITFQPDLSKFKMQSLDKDIVALMVRRAYDIAGSTKDVKVFLNGNKLP------
--VKGFRSYVDMYLKDKVDETGNPLKVIHEQVNHRWEVCLTMSEKGFQQISFVNSIATS-
----------------------------------KGGRHVDYVADQIVAKLVDVVKKKNK
GGVAVKAHQVKNHMWIFVNALIENPTFDSQTKENMTL-------------------Q-P-
-K--S-F--G-S--T--C-Q--L-S--E--K------------------FIKA-------
-----------------AIGC-GIV-ES-ILN-WVK-FK-AQV-QLN-KKC-SAV-KHN-
RIK-GIP-KLD-DAND-AGGRNSTE--C-TL

PF01751 // ENSGT00390000016222_1_Domain_3 (632, 769)

-ILT-EGD-SAK-TL-AVS-GL-GVV-GR
-DKY-GVF-PL-RGK-ILN-VR-EAS-HKQ-IME-NAE-INN-IIK-IVG-LQY-KKN-Y
ED-EDS-LKT-LRY-GKI-MI-MTD-QDQ-DGS-HIK-GL-LI-NFI-HH-NWP-SL-LR
H-RF-LEE-FI-TPIV-KVS-KNK-QEMSFYSL---PEF-EEWKSST-------PNHKKW
KVKYYKG------------------LGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAIS
LAF-SKKQIDDRKEWLTHFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNS
DNE

PF00521 // ENSGT00390000016222_1_Domain_7 (964, 1077)

RSIPSMVDGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTII
N--LAQNFVGSNNLNLLQPIGQFGTRLHGGKDSASPRYIFTMLRPLGSVVIPPKDGSHIK
-----------------------------VTGWSCKIPNFDVREVVIT-----------S
GLPSYKNFKGTIEELAPNQYVISGEVAILDSTTIEISELPIRTWTQTYKEQVLEPMLNGT
EKTPPLITDYREYHTD-TTVKFVVKMTEGKLAEAERVGLHKVFKLQTSLTCNSMVLFDHV
GCLKKYDTVLDILRDFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIEGKIIIE
NKPKKEIIKVLIQRGY-----D---SDPVKAWKEAQQKVPDE--EENEESDNEKETEKSD
SVTDSGPTFNYLLD-MPLWYLTKEKKDELCKLRKEKEQELDTLRKKTPSDLWKEDLAAFI
EELEAVEAKEKQDEQVGLPGKG---------GKGKGKKT--QM-AEVLPSPRGKRVIPRV
TVEMKAEAEKKNRKKIKSENTEGSP-------QEDGMEIESLKQRLEKK--QKRE---PG
TKTKKQTTLPFKPIKKGRKRNPWSESESDMSS-NESDFD---VPPRETEPRKTTTKTKFT
MDLDSDEDSSDFDEN-TQD---EDFVPSD-A-----SPPKTKTSPNNKWI-FLCCLYM--
LFSFPFEEKDLEA---------NDKDSVPLSSSPLAS---DFSAETEIV-NPVSKKNVAV
KKTAA-KSQ-------------SSTSTTGA-K

PF08070 // ENSGT00390000016222_1_Domain_9 (1773, 1882)

KPAPKG-TK-----RNPALNSGVS-QKP
DPAKTK-NRRKRKPSTSDDSDSNFEKIISKAAPSKKSKEES-EDFHLD------FDAAVA
PRAKSSR-------AKKPIKYLEESDEDDLF-------

---------MEVSPLQPVNENMQVNKIKKNEDAKKRLSIERIYQKKT-QLEHILL-----
---------RP-D-T-YI--GSVELVTQQMWVYDEDIGINYREVTFV

PF02518 // ENSGT00390000016222_1_Domain_0 (108, 255)

PGLYKIFDEILVN
AADNKQRDPKMSCIRVTVDPENNLISIWNNGKGIPVVEHKVEKMYVPALIFGQLLTSSNY
DDDEKKVTGGRNGYGAKLCNIFSTKFTVETACREYKKMFKQ--TWMDNMGRAGEMELKPF
SGEDYTCITFQPDLSKFKMKSLDKDIVALMVRRAYDIAGSTKDVKVFLNGNKLP------
--VKGFRSYVDMYLKDKLDETGNPLKVIHEQVNHRWEVCLTMSEKGFQQISFVNSIATS-
----------------------------------KGGRHVDYVADQIVTKLVDVVKKKNK
GGVAVKAHQVKNHMWIFVNALIENPTFDSQTKENMTL-------------------Q-P-
-K--S-F--G-S--T--C-H--L-S--E--K------------------FIKA-------
-----------------AIGC-GIV-ES-ILN-WVK-FK-AQV-QLN-KKC-SAV-KHN-
RIK-GIP-KLD-DAND-AGGRNSTE--C-TL

PF01751 // ENSGT00390000016222_1_Domain_3 (632, 769)

-ILT-EGD-SAK-TL-AVS-GL-GVV-GR
-DRY-GVF-PL-RGK-ILN-VR-EAS-HKQ-IME-NAE-INN-IIK-IVG-LQY-KKN-Y
ED-EDS-LKT-LRY-GKI-MI-MTD-QDQ-DGS-HIK-GL-LI-NFI-

ENSGT00390000016222_1_Linker_3_5 (769, 790)

HH-NWP-SL-LR
H-RF-LEE-

PF16898 // ENSGT00390000016222_1_Domain_5 (790, 962)

FI-TPIV-KIS-KNK-QEMAFYSL---PEF-EEWKSST-------PNHKKW
KVKYYKG------------------LGTSTSKEAKEYFADMKRHRIQFKYCGPEDDAAIS
LAF-SKKQIDDRKEWLTNFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNS
DNERSIPSMVDGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTII
N--LAQNFVGSNNLNLLQPIGQFGTRLHGGKDSASPRYIFTMLSSLARLLFPPKDDHTLK
FLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWSCKIPNFDVREVVNNIRRLMDGEEPLP
MLPSYKNFKGTIEELAPNQYVISGEVAILNSTTIEISELPVRTWTQTYKEQVLEPMLNGT
EKTPPLITDYREYHTD-TTVKFVVKMTEEKLAEAERVGLHKVFKLQTSLTCNSMVLFDHV
GCLKKYDTVLDILRDFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIE
NKPKKELIKVLIQRGY-----D---SDPVKAWKEAQQKVPDE--EENEESDNEKETEKGD
SVTDSGPTFNYLLD-MPLWYLTKEKKDELCRLRNEKEQELDTLKRKSPSDLWKEDLAAFV
EELEAVEAKEKQDEQVGLPGKG---------GKAKGKKA--QM-AEVLPSPCGQRVIPRI
TIEMKADAEKKSKKKIKNENTEGNP-------QEDGMELESLRQRLEKK--QKRE---PG
TKTKKQTTLPFKPIKKGKKRNPWSDSESDRSS-DESNFD---VPPRETEPRRAATKNKFT
VDLDSDEDFSDFDEK-TQD---EDFVPSD-A-----SPPKTKTSSKLNNK-EPKPQK---
SAMSDLEGG--D---------AK--DSVPLSSSPPAT---HFPDETEIT-NPVPKKNVTV
KKTAA-KSQ-------------SSNTTTGVKK

PF08070 // ENSGT00390000016222_1_Domain_9 (1773, 1882)

RAAPKG-TR-----KDPALNSGVS-QKP
DPVKTK-NRRKRKPSTSDDSDSNFEKIVSKAVTSKKSKGES-DDFHMD------FDSALA
PRAKSGR-------AKKPITYLEESDEDDLF-------

---------MEVSPLQPVNENMQVNKTKKNEEAKKRLSIERIYQKKT-QLEHILL-----
---------RP-D-T-YI--GSVESVTQQMWVYDEDIGINYREVTFV

PF02518 // ENSGT00390000016222_1_Domain_0 (108, 255)

PGLYKIFDEILVN
AADNKQRDPKMSCIRVTIDPENNLISIWNNGKGIPVVEHKVEKMYVPALIFGQLLTSSNY
DDEEKKVTGGRNGYGAKLCNIFSTKFTVETASREYKKMFKQ--TWMDNMGRAGEMELKPF
NGEDYTCITFHPDLSKFKMQSLDKDIVALMVRRAYDIAGSTKDVKVFLNGNKLP------
--VKGFRSYVDLYLKDKVDETGNPLKIIHEQVNHRWEVCLTMSEKGFQQISFVNSIATS-
----------------------------------KGGRHVDYVADQIVAKLVDVVKKKNK
GGVAVKAHQVKNHMWIFVNALIENPTFDSQTKENMTL-------------------Q-V-
-K--S-F--G-S--T--C-Q--L-S--E--K------------------FIKA-------
-----------------AIGC-GIV-ES-ILN-WVK-FK-AQV-QLN-KKC-SAV-KHN-
RIK-GIP-KLD-DAND-AGGRNSTE--C-TL

PF01751 // ENSGT00390000016222_1_Domain_3 (632, 769)

-ILT-EGD-SAK-TL-AVS-GL-GVV-GR
-DKY-GVF-PL-RGK-ILN-VR-EAS-HKQ-IME-NAE-INN-IIK-IVG-LQY-KKN-Y
ED-EDS-LKT-LRY-GKI-MI-MTD-QDQ-DGS-HIK-GL-LI-NFI-HH-NWP-SL-LR
H-RF-LEE-FI-TPIV-KVS-KNK-QEMAFYSL---PEF-EEWKSST-------PNHKKW
KVKYYKG------------------LGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAIS
LAF-SKKQIDDRKEWLTHFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNS
DNE

PF00521 // ENSGT00390000016222_1_Domain_6 (964, 1436)

RSIPSMVDGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTII
N--LAQNFVGSNNLNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLARLLFPPKDDHTLK
FLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWSCKIPNFDVREVVNNIRLLMDGEEPLP
MLPSYKNFKGTIEELAPNQYVISGEVAILNSTTIEISELPIRTWTQTYKEQVLEPMLNGT
EKTPPLITDYREYHTD-TTVKFVVKMTEEKLAEAERVGLHKVFKLQTSLTCNSMVLFDHV
GCLKKYDTVLDILRDFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIE
NKPKKELIKVLIQRGY-----D---SDPVKAWKEAQQKVPDE--EENEESDNEKEADKSD
SVADSGPTFNYLLD-MPLWYLTKEKKDELCKLRNEKEQELETLKRKSPSDLWKED

ENSGT00390000016222_1_Linker_6_9 (1436, 1773)

LAAFI
EELEAVEAKEKQDEQIGLPGKG---------GKAKGKKT--QM-AEVLPSPCGKRVIPRV
TVEMKAEAEKKIKKKIKSENTEGSP-------QEDGMEVEGLKQRLEKK--QKRE---PG
TKTKKQTTLPFKPIKKAKKRNPWSDSESDISS-DESNFN---VPPREKEPRRAAAKTKFT
VDLDSDEDFSDADEKT-RD---EDFVPS-DT-----SPQKAETSPK-HTN-K----EPKP
QKST-PSVSDFDA--------DDAKDNVPPSPSSPVA---DFPAVTETI-KPVSKKNVTV
KKTA-AKSQ-------------SSTSTTGAKK

PF08070 // ENSGT00390000016222_1_Domain_9 (1773, 1882)

RAAPKG-AK-----KDPDLDSDVS-KKP
NPPKPK-GRRKRKPSTSDDSDSNFEKMISKAVTSKKPKGES-DDFHLD------LDLAVA
SRAKSGR-------TKKPIKYLEESDEDDLF-------

---------MEVSPLQPLNENMEMNKMKKNEDAKKRLSIERIYQKKT-QLEHILL-----
---------RP---DTYI--GSVELVTQQMWVYDEDIGINYREVTFV

PF02518 // ENSGT00390000016222_1_Domain_0 (108, 255)

PGLYKIFDEILVN
AADNKQRDPKMSCIRVTIDPENNLISIWNNGKGIPVVEHKVEKMYVPALIFGQLLTSSNY
DDDEKKVTGGRNGYGAKLCNIFSTKFTVETASKEYKKMFKQ--TWRDNMGRAGEMELKPF
SGEDYTCITFQPDL

ENSGT00390000016222_1_Linker_0_1 (255, 305)

SKFKMQSLDKDIVALMVRRAYDIAGSTKDVKVFLNGNKLP------
--VK

PF00204 // ENSGT00390000016222_1_Domain_1 (305, 590)

GFRSYVDMYLKDKLDETGNPLKVIHEQVNHRWEVCLTMSEKGFQQISFVNSIATS-
----------------------------------KGGRHVDYVADQIVTKLVDVVKKKNK
GGVAVKAHQVKNHMWIFVNALIENPTFDSQTKENMTLQAKS-------------------
------F--G-----STCQL--------------------------SEKFIKA-------
-----------------AIGC-GIV-ES-ILN-WVK-FK-AQV-QLN-K

ENSGT00390000016222_1_Linker_1_3 (590, 632)

KC-SAV-KHN-
RIK-GIP-KLD-DAND-AGSRNSTE--C-TL

PF01751 // ENSGT00390000016222_1_Domain_3 (632, 769)

-ILT-EGD-SAK-TL-AVS-GL-GVV-GR
-DRY-GVF-PL-RGK-ILN-VR-EAS-HKQ-IME-NAE-INN-IIK-IVG-LQY-KKN-Y
ED-EDS-LKT-LRY-GKI-MI-MTD-QDQ-DGS-HIK-GL-LI-NFI-HH-NWP-SL-LR
H-RF-LEE-FI-TPIV-KVS-KNK-QEMAFYSL---PEF-EEWKSST-------PNHKKW
KVKYYKG------------------LGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAIS
LAF-SKKQIDDRKDWLTHFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNS
DNERSIPSMVDGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTII
N--LAQNFVGSNNLNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLARLLFPPKDDHTLK
FLYDDNQRVEPEWYIPIIPMVLVNGAEGIGTGWSCKIPNFDVREVVNNIRRLMDGEEPLP
MLPSYKNFRGTIEELAPNQYVINGEVAILNSTTIEISELPIRTWTQTYKEQVLEPMLNGT
EKTPPLITDYREYHTD-TTVKFVVKMTEEKLAEAERAGLHKVFKLQTSLTCNSMVLFDHV
GCLKKYDTALDILRDFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIE
NKPKKELIKVLIQRGY-----D---SDPVKAWKEAQQKVPDE--EDNEESDSEKETAKGD
SAADTGPTFAYLLD-MPLWYLTKEKKDELCKQRSEKEQELHTLKKKSPSDLWKEDLAAFV
EELEAVEAKEKQDEQVGLPGKG---------GKPKGKKA--QM-AEVLPSQQGTRVIPRV
TVEMKAEAEKKIKKKIKSENTEGTP-------AEDSVELESLKQRLEKK--QKRE---PG
ARAKKQTTLPFKPIRKGKKRNPWSDSESDMSS-TESNFD---VPPREIEPRRAAAKTKFT
MDLDSDEDFSDSDEKAEE----DDFVPSD-A-----SPPKAKTPPKFTKR-EPKPQK-IT
VSVTG-----LEA--------AGAEDREP-----PA----DLPAQPEAT-KPPPERSATM
KKTTAKGQ--------------SSASTAGTKK

PF08070 // ENSGT00390000016222_1_Domain_9 (1773, 1882)

RAAPKG-AK-----KDPALNSEAS-AKP
DPAKTK-YRRKRKPSTSDDSDSNFEKIISKGATSKKSKAES-DDFQMA------LDSSVT
PRAKSGR-------TKKPIKYLEDSDDDDLF-------

-----------------------------QKDASHXXXXXXXXXXXX-XXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXX

PF02518 // ENSGT00390000016222_1_Domain_0 (141, 255)

ENNLISIWNNGKGIPVVEHKVEKMYVPALIFGQLLTSSNY
DDDEKKVTGGRNGYGAKLCNIFSTKFTVETASREYKKMKQ---TWMDNMGRAGEMELKSF
SGEDYTCITFQPDLSKFKMQSLDKDIVALMVRRAYDIAGSTKDVKVFLNGNRLP------
--IKGFRSYVDMYLKDKVDETGNPLKVIHEQVNHRWEVCLTMSEKGFQQISFVNSIATS-
----------------------------------KGGRHVDYVADQIVTKLADVVKKKNK
GGVAVKAHQTVFPTSSKV------------------------------------------
------------------------------------------------------------
------LAQSFALLLFLAMGC-GIV-ES-ILN-WVK-FK-AQV-QLN-KKC-SAV-KHN-
RIK-GIP-KLD-DAND-AGSRNSAE--C-TL-ILT-EGD-SAK-TL-AVS-GL-GVV-GR
-DKY-GVF-PL-RGK-ILN-VR-EAS-HKQ-IME-NAE-INN-IIK-IVG-LQY-KKN-Y
ED-EDS-LKT-LRY-GKI-MI-MTD-QDQ-DGS-HIK-GL-LI-NFI-HH-NWP-SL-LR
H-RF-LEE-FI-TPIV-KVS-KNK-QELAFYSL---PEF-EEWKSST-------PNHKKW
KVKYYKG------------------LGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAIS
LAF-SKKQIDDRKEWLTHFMEDRRQRKLLGLPEDYLYGQSTTYLTYNDFINKELILFSNS
DNE

PF00521 // ENSGT00390000016222_1_Domain_6 (964, 1448)

RSIPSMVDGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTII
N--LAQNFVGSNNLNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLARLLFPPKDDHTLR
FLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWSCKIPNFDIREVVNNIRRLMDGEEPLP
MLPSYKNFKGTIEELAPNQYVINGEVAILNSTTIEISELPIRTWTQTYKEQGPRPMWNGA
EEPPPLKSNYSEYHSQNNSVRYVVRMTVKKSAERRRRGVHXXXXXXXXXXXXXXVLFDHV
GCLKKYDTALDILRDFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIE
NKPKKELIKVLIQRGY-----D---SDPVKAWKEAQQKVPDE--EENEESDSEKEPEQSV
SAADSGPTFNYLLD-MPLWYLTKEKKDELCRLRNEKEQELETLKKKGPSDLWKEDLAAFI
EELEAVE

ENSGT00390000016222_1_Linker_6_9 (1448, 1773)

AKEKQDEQVGLPGKG---------GKAKGKKA--QM-AEVLPSPRGQRVIPRV
TTEMKAEAEKKIKRKIKSENTEGSP-------KEDGVEVEDLKQRLEKK--QKRE---PG
TKAKKQTTLPFKPVKKGKKRNPWSDSESDMSI-NESNFD---VPPREVEPRRAAAKTKFT
MDLDSDDDFSDFNEKTQDDDDDDDFVS-SHA-----DPPKTKTSPKHTDK-ELKPQQGAM
SAPQ--------D--------SDVEDSAPLAAGAPE--------ETEA-VKPVPKTSVAV
KKTTT-KTL-------------SSTSVTGPKK

PF08070 // ENSGT00390000016222_1_Domain_9 (1773, 1883)

RGPPKG-TR-----KNPASKADVP-QKP
EAPKAMKNPRKRKPSTSDESDSNFEQVVSKAVASKKSKGDS-DNFHLD------LDSAVA
PRAKSSR-------AKKPIKYLEESDEDDLF-------