ENSGT00390000015759_0 : Linker Region Query Results

----------------------MPEMTENETPTKKQHRKKNRETHNAVERHRKKKINAGI
NRIGELIPCSPALKQSKNMILDQAFKYITELKRQNDELLLNGGNNEQAEEIKKLRKQLEE
IQKENGRYIELLKANDICLYDDPTIHWKGNLKNSKVSVV---------------------
IPSDQVQKNIIVYSNGSQPGGNSQGTAVQGITFNVGHNLQKQTANVVPVQRTCNLVTPVS
ISGVYPSENKPWHQTTVSALAANQPVPLCLPAALSAQNILELSTSESESSVLGPTSSSL-
-VAVPVGPEPPQHCSSHTCLNDQNS---SENKKGQESPQVLKKTVPCATSISSSCSATAT
QGQPGSE---SC-RSTQDHRSDLQTTLVVS----VTTAVCSQPPRPAGDSC----MASSS
KGADSASVTMVVAPSVP-GGGMITMPVSTLSANPMDSGWTLSCSLPSSAVSTADLKNMNS
LTRISSAGNTQTTWTTLQLAGNTIQPLSQTPSSAVTPVLNESG--TSPTTANHSRCVAPG
I--SLNNSFPAEGQPVEQVVVTLPSCPPLPMQPLITQPQVKSQPPKSILPLNSAMQVIQM
AQPVGSAVNAAPANQNVIILQPPSTTPCPTVMRAEVPNQTVGQQIVIIQAA-NQNTLPLL
SAPPPGSVRLPVNGASAIIGSNNSVQNVSTPQTFGGKHLVHILPRPTSLS-ASNSTQTFS
VTVSSQQQPQTISLNGQLFALQPVMSSSGTTNQTPMQIIQPTTSEDPNTNVALNTFGALA
SLNQSISQMAGQSCVQLSVSQPVHPQTAANSQITPANCVSLT-TVAPPMTTDNSATLPST
YNLVTTPSVNTVACVP-NTKAKRLNKKPGVKKHLAT-NKSACSLNAVRDVGKSDGPSTEG
SAEPSCN-DGLLESLPGVLP-SAIVSQTN---------SVSVSGS-----HSLNVLNSES
-------------VMPESVPKSKSAEESSPPSQESVTSEQFTMAPAKSKDFLPISQRETS
QDTPPSSLALPDAAKSCTSANVLISSADDAPVLVSQVSHLSSTTSTTSTDCVSEVGVIAD
PCRVQQAS-SDTVPTTGLLKGQGLTALLSGLAKEKDPQ--KSSLSVQVDHPDFSSENSK-
IVDSNVELHP-KQELLLMSSDDRDPGQPHSCIPDQE-VINGSLLTSRQADSPMSTSSGSS
RSFSVASMLPETAREDVTSNAA-TNTCDSCTFVEQTDIVALAARAIFDQENLEKGRAGTQ
VPADIREVPSKPSEASSLE--GDQPFKTQISKESGPGQAEATPNEFNSQDSI---EATVD
--RPLEKPSCSVG-MKTSNASLQVSTSQPPSITSLS-------STLSHPLVSCTGLSQTS
EQTAVPTTVNLTVSSGSYGNQPPG-PSLMTEYSQEHLNTMAGT-VPNTPIQEPL-LKPSH
ESRKDSTKRAVQDDLLLSSAKRQKHCQPAALRLEGLSLMSRTPDSISDQTQMMVGQIPPN
SSNSVVP--ISNPAHGDGLTRLFPPSNNFVVPALRQTEVQCGSQASI-AEQ--QPAQAGQ
HLQALQQH--VPAQGVPHLHSNHVYLKQQ--------------------QQAGQLRERHH
LYQL-QRHVPHAESSVHSQAHSVHQQRTLQQEVQMQKKRNLVQGTQASQLSLQPKHHGTD
QSRPKSGQPHPHHQQMQQQMQQHFGSSQAEKSCENPSTSRNHQ-N----HLSQDILHQ--
QEVGSRQQAPGVSSEHVSGHNPMQRLLTSRGIEQ-QMASQSSIVTRPSDMTCAPHRPERN
RVSSYSAEALIGKTSSNSEQRMGISIQGSRVSDQLEMRSYLDVPRNKSLAIHNMQGRV--
DHT-ASD-IRLSDCQTFKPSGASQQPQNNFEVQSSRNNEIGNP-VSSLRSMQPQAFRISQ
NPGPPPVDRQKRLPYPPVQSIPTGNAIPT-RDNENTCHQSFMQSLLAPHLGDQVIGSQRS
LSEHQRNTQCGPSSAVEYNCPPSHESVHIRRDSESQSRESCDMSLGAINTRNSTLNIPFS
SSSSSGDIQGRNTSPNVSVQKSNPMRITDSHGTKGHMNPPVTTNMHGVARPALPHPSASH
GNADQGP-PVRQTSSSVPQRSRHPLPDS-GGSKIRPPERTRSGNPRHSNVFDPSLPHLPL
STGGSMILGRQQPAAEKRGSIVRFMPDSPQVPNDNSVPDQHTLSQNFGFPFIPEGGMNPP
INANASFIPQVTQPSATRTPALIPVDPQNTLPSFYPPYSPAHPTLSNDISIPYFPNQMFS
NPSTEKVNSGSLNNRFGSILSPPRPVGFAQPSFPLLPDMPPMHMTN-SHLSNFNMTSLFP
EIATAL-PDGSAMSPLLTIANSSASDSSKQSSNRPAHNISHILGHDCSSAV

----------------------MPEMTENETPTKKQHRKKNRETHNAVERHRKKKINAGI
NRIGELIPCSPALKQSKNMILDQAFKYITEMKRQNDELLLNGGNNEQAEEIKKLRKQLDE
LQKENGRYIELLKANDICLYDDPTIHWKGNLKNAKVSVV---------------------
IPSDQVQKNIIVYSNGSQPNGNNQGASVQGITFNVGHNLQKQTANVVPVQRTCNLVTPVT
ISGIYPAENKPRSQSTVSPLASTQVV--------PAGNTLELSITENEQGVLATT--SSQ
NASQSGTDQSLQCSSGNALENGQSL---PKSKNDEGGSKSTKKTVVQGISLPSSASMEAE
KVQHINA---TS-SKTPNSRNEFQENSVIS----TTGTAVVPSVRLSAADS--FSSVNVL
KSTNLISSADMPVTSAA-EGMKAVTVISTLPASPLENCWSFSG---STGVVPSDLKNMSS
LTRMPSAGNTQTTWTTLQLAGNTVQPLSQTPSSIMTALLSEPVNGASAVSPAHSRPLTTS
I--SLNTSLPIDGQAAEQIVVTLPSCPSLPMQPLISQPQVKTQAAGSILPLNSTMQVIQM
AQPVVSAVTGAPANQNVIILQPPNTAPCPPIVRAEVPSQNVSQQIVIIQAA-SQNPLPLL
SAQPSASLRVPVNGTMAVANSNTSVQNAHLPQTFGGKHLVHILPRPSSLP-TSSSTQTFS
VTMSNQQHPQTISLNGQLFALQPVMSSSGASSQAPMQIIQPTTSEDPNTNVALNTFGALA
NLNQSISQMAGQSCLHLSLSHPTNPTTV-HNQITTVNCVSLPASVPPSVPLDGS-VLTSA
SNSTNVSPKKAAAGFLSNTKSKRTNKKQSTKKHLTTNIKVSCAAIPCNDAGKTDSAPVEA
VAKHSKG-EELSENIPAVSQ-ALATLQVT--------GASIS--------PSKEAECSEQ
TVGS------------CPVPETTLAELPAPLPLQLAVSERLALVPPTARDAAPLLPVRQS
QSNPLTSSASSESSSRCEPSGTLTSSQTEAHGTSSQVSGASAVE-SSTACQTSTAGTTSE
SCNVPQGS-SVVMQDVDLLEGQGLTKMLSDLTKERTAVEKSSSFAVQGEHSNFPMENSK-
SGKSTFDSTE-KQELLLMNTEGDALSQHHTCVSDQE-VVSAALIASRQADSPMSTSSGSS
RGFSVASMLPDTTREDVTSNTS-TSTCNNCTFSEQPDIVALAARAIFDQESLEKSGGGMQ
--VNMRDAIPKSTEVATLE-REQQTFKALPVKESNAGPLETASNKFSAQDAV---QTNV-
-GRQVEKPSCSVGGVETSNSSLQISASQSPSITSLSVNNLIHQSRIVHPLVSCSSLSQPS
EPASIPATVGLSLPSSSYVNPSPR-PAMMSEYAQEQLNAIRANSMQAPQLQESRLKQQNH
EGRKDSAKRAVQDDLLLSTAKRQKQCQTAPLRLEGMALMNRTPESIADQTQMLVGQMPSN
SSSSVAS--LSNQGHTDGLNRLFPSNSNFVTPALRQTEVQCNSQPSISEQQ----GSAGQ
HLQPIQHV---PAQGISHLHNNHPYLKQ---------------------QQAGQLRERHH
LYQL-QHHVTHGENSVHSQPHGVHQQRTIQQEVQMQKKRNLIQGTQAPQLSLQQKHHGSD
QTRQKGGQPHPHHQQMQQQMQQHFGASQPEKNCENPATSRNHH-NHPQSHINQDIMHQQQ
QDVSSRQQGS--ASEHVSGHNPMQRLMTSRGLEP-QMVSQASIVTRPSDMTCTPHRQERN
RVSSYSAEALIGKTPSNSEQRIGISLQGPRVSDQLEMRSYIDASRNKGLVIHNMQGRISI
DHTVGSDVQRLSDCQTFKPAGPNQQPAGNFDVQASRNSEIGNS-VSSLRGMQSQAFRIGQ
NTGP-PVERQKRLPYQPVQGIPTGNSLPS-RENENTCHQSFMQSLLAPNLGDQVSGSQRS
IPEHPRNTQCGASSTIEYSCPPARESVHIRRDGDGQNRESCDMSINTINTRNSSLTIPFS
TSSSSGDIQGRNTSPNISVQKSNPMRMTDSHGTKSHMNTPVSSNMHGVVRPTHPHPAVSH
GNGEQGQPSVRQPNSSVTQRSRHPLQDN-NGSKIRQPERNRSGNQRHGNVFDPSLPHLPL
STSSSMILGRQQSAIEKRGSIVRFMSDGPQVSNDNAASDQHTLSQNFGFPFIPEGGMNPP
INANTSFIPPVTQPSATRTPALIPVDPQNTLPSFYPPYSPAHPTLSNDISIPYFPNQMFP
NPSTEKPSSGGLNNRFGSILSPPRPVGFAQPSFPLLPDMPPMHMTNTSHLSNFNLTSLFP
EIATALPPDGSAMSPLLSIANTSASDSSKQPSNRPAHNISHILGHDCSSAV

----------------------MPEMTENETPTKKQHRKKNRETHNAVERHRKKKINAGI
NRIGELIPCSPALKQSKNMILDQAFKYITELKRQNDELLLNGGNNEQAEEIKKLRKQLEE
IQKENGRYIELLKANDICLYDDPTIHWKGNLKNSKVSVV---------------------
IPSDQVQKNIIVYSNGNQPGGNSQGTAVQGITFNVSHNLQKQTANVVPVQRTCNLVTPIS
ISGVYPSENKPWHQTTVPALATNQPVPLCLPAAISAQSVLELPTSESESSVLGASSGSL-
-IAVSVGPEPHQRHSLHTCLNDQNS---SENKNGQENPKLLKKMTPCAVNIPLSSSAAAT
KVHHGNK---SC-LSIQDFRGDFQNTFVVS----VTTTVCSQPPRTADDSS----PMSIS
KSADLTSTATVVASSAP-GVGKATIPISTLSGNPLDNGWTLSCSLPSSSVSTSDLKNINS
LTRISSAGNTQTTWTTLQLAGNTIQPLSQTPSSAVTPVLNESG--TSPTTSNHSRHVATG
I--NLNNSFPADGQPVEQVVVTLPSCPSLPMQPLIAQPQVKSQPPKNILPLNSAMQVIQM
AQPVGSAVNAAPTNQNVIILQPPSTTPCPTVMRAEVPNHTVGQQIVIIQAA-NQNPLPLL
SAPPPGSVRLPINGANTVIGSNNSVQNVSTPQTFGGKHLVHILPRPSSLS-VSNSTQTFS
VTMSN-QQPQTISLNGQLFALQPVMSSSGTTNQTPMQIIQPTTSEDPNTNVALNTFGALA
SLNQSISQMAGQSCVQLSISQPANAQTAANSQTTTANCVSLAT-AAPPVTTDSSATLAST
YNLVSTSSMNTVACLPPNMKSKRLNKKPGARKHLAA-NKSACPLNPVRDVSKLDCPNPES
SAELPCN-DGLLESFPAVLP-PVSMSQAN---------SVSVSAS-----HSLGVLNSES
-------------LIPESVSKSKSIEKSSSPSQESVTSEHFAMAPAKSKDSTPNLQQETP
QDKPPSHLALSDAAKPCTSANVLIPSPSDPHILVSQVSGLSSTTSTTSTDCVSEVEIIAE
PCTVEQDS-SDTMQTTGLLKGQGLTTLLSDLAKKKNPQ--KSSLSDQMDHPDFSSENPK-
IVDSSVNLHP-KQELLLMNSDDRDPPQHHSCLPDQE-VINGSLITSRQADSPMSTSSGSS
RSFSVASMLPETTREDVTSNAT-ANTCDSCTFVEQTDIVALAARAIFDQENLEKGRVGLQ
--ADIREVASKPSEASSLE--GDPPFKSQIPKENGTGQAEATPNEFNSQDSI---EATME
--RPLEKPSCSLG-IKTSNAPLQASPSQPPSITSLSVNNLIHQSSISHPLASCAGLSPTS
EQTTVPATVNLTVSSSSYDSQPPG-PSLMTEYSQEQLNTMTST-IPNSQIQEPL-LKPSH
ESRKDSAKRAVQDDLLLSSAKRQKHCQPAPLRLESMSLMSRTPDTISDQTQMMVSQIPPN
SSNSVVP--VSNPAHGDGLTRLFPPSNNFVAPALRQTEVQCGSQPSV-AEQ--QQTQAGQ
HLQALQQH--VPAQGVSHLHSNHLYIKQQQQQQQ-----------QQQQQQAGQLRERHH
LYQM-QHHVPHAESSVHSQPHNVHQQRTLQQEVQMQKKRNLVQGTQASQLSLQPKHHGTD
QSRSKSGQPHPHHQQMQQQMQQHFGSSQTEKSCENPSTSRNHH-NHPQNHLNQDIMHQQ-
QDVGSRQQGSGVSSEHVSGHNPMQRLLTSRGLEQ-QMVSQPSIVTRSSDMTCTPHRPERN
RVSSYSAEALIGKTSSNSEQRMGISIQGSRVSDQLEMRSYLDVPRNKSLAIHNMQGRV--
DHTVASD-IRLSDCQTFKPSGASQQPQSNFEVQSSRNNEIGNP-VSSLRSMQSQAFRISQ
NTGPPPIDRQKRLPYPPVQSIPTGNGIPS-RDSENTCHQSFMQSLLAPHLSDQVIGSQRS
LSEHQRNTQCGPSSAIEYNCPPTHENVHIRRESDSQNRESCDMSLGAINTRNSTLNIPFS
SSSSSGDIQGRNTSPNVSVQKSNPMRITDSHATKGHMNPPVTTNMHGVARPALPHPSVSH
GNGDQGP-PVRQANSSVPQRSRHPLQDS-SGSKIRQPERNRSGNQRQSNVFDPSLPHLPL
STGGSMILGRQQPATEKRGSIVRFMPDSPQVPNDNSGPDQHTLSQNFGFSFIPEGGMNPP
INANASFIPQVTQPSATRTPALIPVDPQNTLPSFYPPYSPAHPTLSNDISIPYFPNQMFS
NPSTEKVNSGSLNNRFGSILSPPRPVGFAQPSFPLLPDMPPMHMTN-SHLSNFNMTSLFP
EIATAL-PDGSAMSPLLTIANSSASDSSKQSSNRPAHNISHILGHDCSSAV

MVPAVGAPPPSPPSPPVLFSETMPEMTENDTPTKKQHRKKNRETHNAVERHRKKKINAGI
NRIGELIPCSPALKQSKNMILDQAFKYITEMKRQNDELLLNGGNNEQAEEIKKLRKQLDE
LQKENGRYIELLKANDICLYDDPTIHWKGNLKNAKVSVV---------------------
IPSDQVQKNIIVYSNGSQPNGNNQGASVQGITFNVGHNLQKQTANVVPVQRTCNLVTPVT
ISGIYPAENKPRSQSTVSPLAPTQVV--------PAGNTLELSIPENEQGVLATATASSQ
NASQSRTEQGLQCSSDNALQNGQSL---PKSKNDEGGSKSTKKTVVQEISLPSSASMEVE
KVQRMNT---TS-SKTPNSRNEFQESSVIS----TTGTAVVPSVRLSTADS--FSSVNVL
KSTNLISSADMPTTSAA-EGMKAVTVISTLPASPLENCWSFSG---STGVVPSDLKNMSS
LTRMPSAGNTQTTWTTLQLAGNTVQPLSQTPSSIMTALLSEPVNGASTVSPAHSRPLTTS
I--SLNTSLPTDGQAAEQIVVTLPSCPSLPMQPLISQPQVKTQAAGSILPLNSTMQVIQM
AQPVASAVTGAPANQNVIILQPPNTAPCPPIVRAEVPSQNVSQQIVIIQAA-SQNPLPLL
SAQPSASVRVPVNGPVAVANSSNSVQNAHLPQTFGGKHLVHILPRPSSLP-SSSSTQTFS
VTMSNQQHPQTISLNGQLFALQPVMSSSGASNQAPMQIIQPTTSEDPNTNVALNTFGALA
NLNQSISQMAGQSCLHLSLSHPTNPTTV-HNQITTVNCVSLPASVPPSVPVEGS-VLTSA
SNSTSVSPKKAAAGFLSNTKSKRTNKKQSTKKHLAANIKVSCPAIPCKDAGKADSVPVEA
VAKHSKG-EGLPENIPAASQ-ALATLQVS--------GASIS--------PSKEAECSEQ
AVGS------------CPVPETTLAELPTPSPLQLAVSERLALVPPTARDAAPLLPVRQS
QSNPLTSTASSESSSRCEPPGTLTSSQTEAHGTSPQVSGASAVE-SSTAGQTSTAGTTSE
SCSVPQGS-SVVMQDVDLLEGQGLTKMLSDLTKERTVVEKSSSFAVQGEHSNFPMESSK-
SVESNVDLPE-KQELLLMNTEGDALSQHHTCVSDQE-VVSAALIASRQADSPMSTSSGSS
RGFSVASMLPDTTREDVTNNTS-TSTCNNCTFSEQPDIVALAARAIFDQESLEKSGGGIQ
--VNMRDAISKSTEVATLE-REQQTFKPLPVKESNAGPLETASNKFSAQDTV---QTNV-
-DRQVEKPSCSVGGVETSNSSLQISASQSPSITSLSVNNLIHQSRIVHPLVSCSSLSQPS
EPASIPATVGLSLPSSSYVNPSPR-PAMMSEYAQEQLNAIRANSMQAPQLQESHLKQQNH
EGRKDSAKRAVQDDLLLSTAKRQKQCQTAPLRLEGMALMNRTPEGIADQTQMLVGQMPSN
SSNSVSS--LSSQGHTDGLNRLFPSNSNFVTPALRQTEVQCSSQPPISEQQ----GTAGQ
HLQPIQHV---PGQGISHLHNNHPYLKQ---------------------QQAGQLRERHH
LYQL-QHHVTHGENSVHSQPHGVHQQRTIQQEVQMQKKRNLIQGTQAPQLSLQQKHHGSD
QTRQKGGQPHPHHQQMQQQMQQHFGASQPEKNCENPATSRNHH-NHPQSHINQDIMHQQQ
QDVSSRQQGS--ASEHVSGHNPMQRLMTSRGLEP-QMVSQASIVTRPSDMTCTPHRQERN
RVSSYSAEALIGKTPSNSEQRIGISLQGPRVSDQLEMRSYIDASRNKGLVIHNMQGRISI
DHTVGSDVQRLSDCQTFKPAGPNQQPAGNFDVQASRNSEIGNS-VSSLRGMQSQAFRIGQ
NTGP-PIERQKRLPYQPVQGIPTGNSLPS-RENENTCHQSFMQSLLAPNLGDQVSGSQRS
IPEHPRNTQCGASSTIEYSCPPARESVHIRRDGDGQNRESCDMSISTINTRNSSLTIPFS
TSSSSGDIQGRNTSPNISVQKSNPMRMTDSHGTKSHMNTPVSSNMHGVVRPTHPHPAVSH
GNGEQGQPSVRQPNSSVTQRSRHPLQDN-NSSKIRQPERNRSGNQRHGNVFDPSLPHLPL
STSSSMILGRQQSAIEKRGSIVRFMSDGPQVSNDNAASDQHTLSQNFGFPFIPEGGMNPP
INANTSFIPPVTQPSATRTPALIPVDPQNTLPSFYPPYSPAHPTLSNDISIPYFPNQMFP
NPSTEKPSSGGLNNRFGSILSPPRPVGFAQPSFPLLPDMPPMHMTNTSHLSNFNLTSLFP
EIATALPPDGSAMSPLLSIANTSASDSSKQPSNRPAHNISHILGHDCSSAV

----------------------MPEMTENETPTKKQHRKKNRETHNAVERHRKKKINAGI
NRIGELIPCSPALKQSKNMILDQAFKYITELKRQNDELLLNGGNNEQAEEIKKLRKQLEE
IQKENGRYIELLKANDICLYDDPTIHWKGNLKNSKVSVV---------------------
IPSDQVQKNIIVYSNGNQPGGNSQGTAVQGITFNVSHNLQKQTANVVPVQRTCNLVTPIS
ISGVYPSENKPWHQTTVPALATNQPVPLCLPAAISAQSILELPTSESESSVLGASSGSL-
-IAVSVGPEPHQHHSLHTCLNDQNS---SENKNGQENPKLLKKMTPCAINIPLSSSATAT
KVHHGNK---SC-LSIQDFRGDFQNTFVVS----VTTTVCSQPPGTADDSS----PMSIS
KSADLTSTATVVASSAS-GVGKATIPISTLSGNPLDNGWTLSCSLPSSSVSTSDLKNINS
LTRISSAGNTQTTWTTLQLAGNTIQPLSQTPSSAVTPVLNESG--TSPTTSNHSRHVATG
I--NLNNSFPADGQPVEQVVVTLPSCPSLPMQPLIAQPQVKSQPPKNILPLNSAMQVIQM
AQPVGSAVNAAPTNQNVIILQPPSTTPCPTVMRAEVPNQTVGQQIVIIQAA-NQNPLPLL
SAPPPGSVRFPINGANTVIGSNSSVQNVSTPQTFGGKHLVHILPRPSSLS-VSNSTQTFS
VTMSN-QQPQTISLNGQLFALQPVMSSSGTTNQTPMQIIQPTTSEDPNTNVALNTFGALA
SLNQSISQMAGQSCVQLSVSQPANAQTAANSQTTTANCVSLAT-AAPPVTTDSSATLAST
YNLVSTSSMNTVACLPPNMKSKRLNKKPGARKHLAA-NKSACPLNPVRDVSKLDCPNTEG
SAEPPCN-GGLLESFPAVLP-SVSMSQAN---------SVSVSAS-----HSLGVLNSES
-------------LIPESVSKSKSTEKSSSPSQEYVTSEHFAMTPAKSKDSTPNLQQETP
QDKPPSSLALSDAAKPCTSANVLIPSPSDPHILVSQVSGLSSTTSTTNTDCVSEVEIIAE
PCRVEQDS-SDTMQTTGLLKGQGLTTLLSDLAKKKNPQ--KSSLSDQMDHPDFSSENPK-
IVDSSVNLHP-KQELLLMNSDDRDPPQHHSCLPDQE-VINGSLITGRQADSPMSTSSGSS
RSFSVASMLPETTREDVTSNAT-ANTCDSCTFVEQTDIVALAARAIFDQENLEKGRVGLQ
--ADIREVASKPSEASSLE--GDPPFKSQIPKENGTGQAEATPNEFNSQDSI---EATME
--RPLEKPSCSLG-IKTSNAPLQASASQPPSLTSLSVNNLIHQSSISHPLASCAGLSPTS
EQTTVPATVNLTVSSSSYDSQPPG-SSLMTEYSQEQLNTMTST-IPNSQIQEPL-LKPSH
ESRKDSAKRAVQDDLLLSSAKRQKHCQPAPLRLESMSLMSRTPDTISDQTQMMVSQIPPN
SSNSVVS--VSNPAHGDGLTRLFPPSNNFVAPALRQTEVQCGSQPSVVAEQ--QQTQASQ
HLQALQQH--VPAQGVSHLHSNHLYIKQQQQQQ-----------QQQQQQQAGQLRERHH
LYQM-QHHVPHAESSVHSQPHNVHQQRTLQQEVQMQKKRNLVQGTQASQLSLQPKHHGTD
QSRSKSGQPHPHHQQMQQQMQQHFGSSQTEKSCENPSTSRNHH-NHPQNHLNQDIMHQQ-
QDVGSRQQGSGVSSEHVSGHNPMQRLLTSRGLEQ-QMVSQPSIVTRSSDMTCTPHRPERN
RVSSYSAEALIGKTSSNSEQRMGISIQGSRVSDQLEMRSYLDVPRNKSLGIHNMQGRV--
DHTVASD-IRLSDCQTFKPSGASQQPQSNFEVQSSRNNEIGNP-VSSLRSMQSQAFRISQ
NTGPPPIDRQKRLPYPPVQSIPTGNGIPS-RDSENSCHQSFMQSLLAPHLSDQVIGSQRS
LSEHQRNTQCGPSSAIEYNCPPTHENVRIRRESDSQNRESCDMSLGAINTRNSTLNIPFS
SSSSSGDIQGRNTSPNVSVQKSNPMRITDSHATKGHMNPPVTTNMHGVARPALPHPSVSH
GNGDQGP-PVRQANSSVPQRSRHPLQDS-SGSKIRQPERNRSGNQRQSNVFDPSLPHLPL
STSGSMILGRQQPATEKRGSIVRFMPDSPQVPNDNPGPDQHTLSQNFGFSFIPEGGMNPP
INANASFIPQVTQPSATRTPALIPVDPQNTLPSFYPPYSPAHPTLSNDISIPYFPNQMFS
NPSTEKVNSGSLNNRFGSILSPPRPVGFAQPSFPLLPDMPPMHMTN-SHLSNFNMTSLFP
EIATAL-PDGSAMSPLLTIANSSASDSSKQSSNRPAHNISHILGHDCSSAV

----------------------MPEMTENETPTKKQHRKKNRETHNAVERHRKKKINAGI
NRIGELIPCSPALKQSKNMILDQAFKYITELKRQNDELLLNGGNNEQAEEIKKLRKQLEE
IQKENGRYIELLKANDICLYDDPTIHWKGNLKNSKVSVV---------------------
IPSDQVQKNIIVYSNGNQPGGNSQGTAVQGITFNVSHNLQKQTANVVPVQRTCNLVTPIS
ISGVYPSENKPWHQTTVPALATNQPVPLCLPAAISAQSVLELPTSESESSVLGASSGSL-
-IAVSVGPEPHQHHSLHTCLNDQNS---SENKNGQENPKLLKKMTPCAVNIPLSSSAAAT
KVHHGNK---SC-LSIQDFRGDFQNTFVVS----VTTTVCSQPPRTADDSS----PMSIS
KSADLTSTATVVASSAP-GVGKATIPISTLSGNPLDNGWTLSCSLPSSSVSTSDLKNINS
LTRISSAGNTQTTWTTLQLAGNTIQPLSQTPSSAVTPVLNESG--TSPTTSNHSRHVATG
I--NLNNSFPADGQPVEQVVVTLPSCPSLPMQPLIAQPQVKSQPPKNILPLNSAMQVIQM
AQPVGSAVNAAPTNQNVIILQPPSTTPCPTVMRAEVPNHTVGQQIVIIQAA-NQNPLPLL
SAPPPGSVRLPINGANTVIGSNNSVQNVSTPQTFGGKHLVHILPRPSSLS-VSNSTQTFS
VTMSN-QQPQTISLNGQLFALQPVMSSSGTTNQTPMQIIQPTTSEDPNTNVALNTFGALA
SLNQSISQMAGQSCVQLSISQPANAQTAANSQTTTANCVSLAT-AAPPVTTDSSATLAST
YNLVSTSSMNTVACLPPNMKSKRLNKKPGARKHLAA-NKSACPLNPVRDVSKLDCPNPES
SAELPCN-DGLLESFPAVLP-PVSMSQAN---------SVSVSAS-----HSLGVLNSES
-------------LIPESVSKSKSIEKSSSPSQESVTSEHFAMAPAKSKDSTPNLQQETP
QDKPPSHLALSDAAKPCTSANVLIPSPSDPHILVSQVSGLSSTTSTTSTDCVSEVEIIAG
PCTVEQDS-SDTMQTTGLLKGQGLTTLLSDLAKKKNPQ--KSSLSDQMDHPDFSSENPK-
IVDSSVNLHP-KQELLLMNSDDRDPPQHHSCLPDQE-VINGSLITSRQADSPMSTSSGSS
RSFSVASMLPETTREDVTSNAT-ANTCDSCTFVEQTDIVALAARAIFDQENLEKGRVGLQ
--ADIREVASKPSEASSLE--GDPPFKSQIPKENGTGQAEATPNEFNSQDSI---EATME
--RPLEKPSCSLG-IKTSNAPLQASPSQPPSITSLSVNNLIHQSSISHPLASCAGLSPTS
EQTTVPATVNLTVSSSSYDSQPPG-PSLMTEYSQEQLNTMTST-IPNSQIQEPL-LKPSH
ESRKDSAKRAVQDDLLLSSAKRQKHCQPAPLRLESMSLMSRTPDTISDQTQMMVSQIPPN
SSNSVVP--VSNPAHGDGLTRLFPPSNNFVAPALRQTEVQCGSQPSV-AEQ--QQTQAGQ
HLQALQQH--VPAQGVSHLHSNHLYIKQQQQQQQ----------QQQQQQQAGQLRERHH
LYQM-QHHVPHAESSVHSQPHNVHQQRTLQQEVQMQKKRNLVQGTQASQLSLQPKHHGTD
QSRSKSGQPHPHHQQMQQQMQQHFGSSQTEKSCENPSTSRNHH-NHPQNHLNQDIMHQQ-
QDVGSRQQGSGVSSEHVSGHNPMQRLLTSRGLEQ-QMVSQPSIVTRSSDMTCTPHRPERN
RVSSYSAEALIGKTSSNSEQRMGISIQGSRVSDQLEMRSYLDVPRNKSLAIHNMQGRV--
DHTVASD-IRLSDCQTFKPSGASQQPQSNFEVQSSRNNEIGNP-VSSLRSMQSQAFRISQ
NTGPPPIDRQKRLPYPPVQSIPTGNGIPS-RDSENTCHQSFMQSLLAPHLSDQVIGSQRS
LSEHQRNTQCGPSSAIEYNCPPTHENVHIRRESDSQNRESCDMSLGAINTRNSTLNIPFS
SSSSSGDIQGRNTSPNVSVQKSNPMRITDSHATKGHMNPPVTTNMHGVARPALPHPSVSH
GNGDQGP-PVRQANSSVPQRSRHPLQDS-SGSKIRQPERNRSGNQRQSNVFDPSLPHLPL
STGGSMILGRQQPATEKRGSIVRFMPDSPQVPNDNSGPDQHTLSQNFGFSFIPEGGMNPP
INANASFIPQVTQPSATRTPALIPVDPQNTLPSFYPPYSPAHPTLSNDISIPYFPNQMFS
NPSTEKVNSGSLNNRFGSILSPPRPVGFAQPSFPLLPDMPPMHMTN-SHLSNFNMTSLFP
EIATAL-PDGSAMSPLLTIANSSASDSSKQSSNRPAHNISHILGHDCSSAV

----------------------MPEMTENETPTKKQHRKKNRETHNAVERHRKKKINAGI
NRIGELIPCSPALKQSKNMILDQAFKYITELKRQNDELLLNGGNNEQAEEIKKLRKQLEE
IQKENGRYIELLKANDICLYDDPTIHWKGNLKNSKVSVV---------------------
IPSDQVQKNIIVYSNGSQPGGNSQGTAVQGITFNVGHNLQKQTANVVPVQRTCNLVTPVS
ISGVYPSENKPWHQTTVSALAANQPVPLCLPAALSAQNILELSTSESESSVLGPTSSSL-
-IAVPVGPEPPQHRSSHTCLNDQNS---SENKKGQESPQVLKKTVPCATSISSSCSATAT
QGQPGSE---SC-LSAQDHRSDLQTTLVVS----VTTTVCSQPPRPVGDSC----VASSS
KGADSASVTMVVAPSVP-GGGMTAMPVSTLSANPMDSGWTLSCSLPSSAVSASDLKNMNS
LTRISSAGNTQTTWTTLQLAGNTIQPLSQTPSSAVTPVLNESG--TSPTTANHSRCVAPG
I--SLNNSFPAEGQPVEQVVVTLPSCPPLPMQPLITQPQVKSQPPKSILPLNSAMQVIQM
AQPVGSAVNAAPANQNVIILQPPSTTPCPTVMRAEVPNQTVGQQIVIIQAA-NQNTLPLL
SAPPPGSVRLPVNGASAIIGSNNSVQNVSTPQTFGGKHLVHILPRPTSLS-ASNSTQTFS
VTVSSQQQPQTISLNGQLFALQPVMSSSGTTNQTPMQIIQPTTSEDPNTNVALNTFGALA
SLNQSISQMAGQSCVQLSVSQPVHPQTAANSQITPANCISLT-TVAPPVTTDNSATPPST
YNLVTTPSVNTVACLP-NTKAKRLNKKPGVKKHLAT-NKSACSLNPVRDGGKSDGPSTEG
SAEPSCN-DGLLESLPGVLP-SAIVSQTN---------SVSVSGS-----HSLNVLNSES
-------------VMPESVPKSKSAEESSSPSQESVTSEQFTMAPAKSKDFLPISQRETS
QDKPPSSLALPEAAKSCTSASVLISSVNDAPVLASQVSHLSSATSTTSTDCVSEVEVIAD
PCRAEQES-SDTVQTAGLLKGQGLTALLSGLAKEKDPQ--KSSLSVQVDHPDFSSENSK-
IVDSNVELHP-KQELLLMNSDDRDPGQPHSCIPDQE-VINGSLLTSRQADSPMSTSSGSS
RSFSVASMLPETAREDVTSSAT-TNTCDSCTFVEQTDIVALAARAIFDQENLEKGRAGTQ
VPADIREVPSKPSEASSLE--GDQPFKTQIPKENGPGQVEATPNEFNSQDSI---EATVD
--RPLEKSSCSIG-MKTSNASLQVSTSQPPSITSLSVNNLIHQSTLSHPLVSCTGLSQTS
GQTAVPTTVNLTVSSGSYGSQPPG-PSLMTEYSQEQLNTMAGT-VPNTPIPEPL-LKPSH
ESRKDSAKRAVQDDLLLSSAKRQKHCQPAPLRLEGLSLMSRTPDSISDQTQMMVGQIPPN
SSNSVVP--ISNPAHGDGLTRLFPPSNNFVVPALRQTEVQCSSQASI-AEQ--QPAQAGQ
HLQALQQH--VPAQGVPHLHSNHLYLKQQ--------------------QQAGQLRERHH
LYQL-QRHVPHAESSVHSQPHSVHQQRTLQQEVQMQKKRNLVQGTQASQLSLQPKHHGTD
QSRPKSGQPHPHHQQMQQQVQQHFGTSQAEKGCENPSTSRNHQ-N----HLSQDILHQ--
QEVGSRQQAPGVSSEHVSGHNPMQRLLTSRGIEQ-QMASQSSIVTRPSDMTCAPHRPERN
RVSSYSAEALIGKTSSNSEQRMGISIQGSRVSDQLEMRSYLDVPRNKSLAIHNMQGRV--
DHT-ASD-IRLSDCQTFKPSGASQQPQNNFEVQSSRNNEIGNP-VSSLRSMQPQAFRISQ
NPGPPPVDRQKRLPYPPVQSIPTGNAIPT-RDSENTCHQSFMQSLLAPHLGDQVIGSQRS
LSEHQRNTQCGPSSAIEYNCPPSHESVHIRRESESQSRESCDMSLGAINTRNSTLNIPFS
SSSSSGDIQGRNTSPNVSVQKSNPMRITDSHGAKGHMNPPVTTNMHGVVRPALPHPSASH
GNADQGP-PVRQTSSSVPQRSRHPLQDS-SGSKIRPPERTRSGNPRHSNVFDPSLPHLPL
STGGSMILGRQQPAAEKRGSIVRFMPDSPQVPNDNSVPDQHTLSQNFGFPFIPEGGMNPP
INANASFIPQVTQPSATRTPALIPVDPQNTLPSFYPPYSPAHPTLSNDISIPYFSNQMFS
NPSTEKVNSGSLNNRFGSILSPPRPVGFAQPSFPLLPDMPPMHMTN-SHLSNFNMTSLFP
EIATAL-PDGSAMSPLLTIANSSASDSSKQSSNRPAHNISHILGHDCSSAV

----------------------MPEMTENDTPMKKQHRKKNRETHNAVERHRKKKINAGI
NRIGELIPCSPALKQSKNMILDQAFKYITELKRQNDELLLNGGNNEQXXXXXXXXXXXXX
XQKEKGRYIELLKPNDICLYDDPTIHWKGNLKASKVSVV---------------------
IPSDQVQKNIIVYPNGSQSCGHGQGAAVQGITFSVGHHLQKQTANVVPVQRACNLVTPVS
ISGVFSSENKPWHQTTVSALAANQPVPLCLPATIPAQKILELSTSEGESSVLGITSGSL-
-IAVPVGPEPHQPRSLNTCLNDHNS---SDNKNGQESPKLLKTSTPCAISSTASSSATAS
KVCPGNE---------QDLRGDFPNSLVVS----VTTTVCSQPPRSVSDSS----PVTVS
KSADSTRTTTVLAPAAPAGAGKTTTAVSTLVANSLDSGWTLSCSLPSSTVSASDLKNMSS
LTRISSAGNTQTTWTTLQLTGNTIQPLSQTSSSTVTPVLNESG--TSPTASNHSRPIAPA
V--NLNNSFPAEGQAVEQVVVTLXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XLNQSISQMGGQSCVQLSFNRPVNSQTAAKSQTPPANCVSLT-TVAPPMTTDNSAISL--
SHPVTTSSVTTVTCLS-TVKSKRLNKKPAAKRHLTA-SKPVCPLNPGHDAGKLDCPGAEG
SVEPSCN-DRPSESLPSVLP-PVAVSQEN--------A------VGVPASQSLEVLDSQS
-------------VTPESASKYMSVEESPSPSQESVTSEHSAVAPENPKESTPLLQREAS
QDEPPTSSALSGATTPCTSAHVLIPSPSDTHVLVSQVSDLSTTTSTTSTDCVSEVEIIAE
PCRVEPDT----AQSTSVLKGHGLTTLLSDLAKEKDPQ--KSPLSVQMDHPDFSSGNPK-
VVDSGVDLHP-KQELLLMNNDDRDPAQHHACLPDQE-VIAGSLLTSRQADSPMSTSSGSS
RSFSVASMLPETAREDVTSHAA-TNTCDSCTFAEQTDIVALAARAIFDQENLEKGRVGIQ
--ADLREAASKPSEASSLA--GDQPCKSQIPKENGPGQAEAAPREFTSQDSM---EAAM-
-----EKSSCSLG-IKTSSASLQVSASQPSSVTSLSVNNLIHPSSIGHPLVSCASLSQTS
EPTTAPTTVSLAVSSSSYGGQPPG-PSLMTEYSQEQPLNTLTSTIPNSQIQEPL-LKSGH
EGRKDSAKRAVQEELLLSSAKRQKHCQPAPLRLENMSLMSRTPDSISDQTQMMVSQIPPN
SSNSVVP--ASNPAHGDSLTRLFPPSNNFVAPVLRQAEVQCSSQPPV-AEQ--QQTQASQ
HLQTLQQH--VPTQGVSHLHSNHLYIKQQQQ------------------QQAGQLRERHH
LYQL-QHHVPHAESAVHSQPHNVHQQRTLQQEVQMQKKRNLVAGTQASQLSLQPKHHG-D
QSRPKSGQPHPHHQQLQ-HMPGLFGSSLSDNNCDNASSSRTPH-NHPQNGLFPNIMHQQ-
QDVGSRQQGSAVSSEHVSGHTPMQRLLTSRALEQ-QMVSQPSIVTRPSDMTCTPHRPERN
RVSSYSAEALIGKTSSNSEQRMGLPIQGSRVSDQLEMRSYLDIPRNKSLALHNMQGRV--
DHTVVSE-IRLSDCQTFKPSGASQPPQSNFELQSSRNNEIGNPPVSSLRGMQSQAFRISQ
NTGPPPIDRQKRLPYPPVQSIPTGNAIPP-RDSENACHQSFMQSLLAPHLGDQVIGNQRS
LSEHQRNTQCGPSSAIEYNCPPAHESVHLRRESESQNRESCDMSLGAINTRNSALNIPFS
SSSSSGDIQGRNTSPNVSVQKSNPMRITDSHGTKGHMNPPVTTNMHGVARPALPHPSVSH
GSADQGAA-GR-QANSVGQRSRHPLQDS-SGSKIRQPERNRSGNQRHSNVFDPSLPHLPL
STSGSMILGRQQPTAEKRGSIVRFMPDSPQVPNDNSGPDQHTLSQNFGFPFIPEGGMNPP
INANTSFIPQVSQPSATRTPALIPVDPQNTLPSFYPPYSPAHPTLSNDISIPYFSNQMFS
NPSSEKVNGGSLNNRFGSILSPPRPVGFAQPSFPLLPDMPPMHMTN-SHLSNFNMTSLFP
EIATAL-PDGSAMSPLLTIANSSASDSSKQSSNRPAHNISHILGHDCSSAV

----------------------MPEMTENETPTKKQHRKKNRETHNAVERHRKKKINAGI
NRIGELIPCSPALKQSKNMILDQAFKYITELKRQNDELLLNGGNNEQAEEIKKLRKQLEE
IQKENGRYIELLKANDICLYDDPTIHWKGNLKNSKVSVV---------------------
IPSDQVQKNIIVYSNGNQPGGNSQGTAVQGITFNVSHNLQKQTANVVPVQRTCNLVTPIS
ISGVYPSENKPWHQTTVPALATNQPVPLCLPAAISAQSILELPTSESESSVLGASSGSL-
-IAVSVGPEPHQHHSLHTCLNDQNS---SENKNGQENPKLLKKMAPCAINIPLSSSATAT
KVHHGNK---SC-LSIQDFRGDFQNTFVVS----VTTTVCSQPPGTADDSS----PMSIS
KSADLTSTATVVASSAP-GVGKATIPISTLSGNPLDNGWTLSCSLPSSSVSTSDLKNINS
LTRISSAGNTQTTWTTLQLAGNTIQPLSQTPSSAVTPVLNESG--TSPTTSNHSRHVATG
I--NLNNSFPADGQPVEQVVVTLPSCPSLPMQPLIAQPQVKSQPPKNILPLNSAMQVIQM
AQPVGSAVNAAPTNQNVIILQPPSTTPCPTVMRAEVPNQTVGQQIVIIQAA-NQNPLPLL
SAPPPGSVRLPINGANTVIGSNNSVQNVSTPQTFGGKHLVHILPRPSSLS-VSNSTQTFS
VTMSN-QQPQTISLNGQLFALQPVMSSSGTTNQTPMQIIQPTTSEDPNTNVALNTFGALA
SLNQSISQMAGQSCVQLSISQPANAQTAANSQTTTANCVSLAT-AAPPVTTDSSATLAST
YNLVSTSSMNTVACLPPNMKSKRLNKKPGARKHLAA-NKSACPLNPVRDVSKLDCPNTEG
SAEPPCN-DGLLESFPAVLP-SVSMSQAN---------SVSVSAS-----HSLGVLNSES
-------------LIPESVSKSKSTEKSSSPSQESVTSEHFAMAPAKSKDSTPNLQQETP
QDKPPSSLALSDAAKPCTSANVLIPSPSDPHILVSQVSGLSSTTSTTSTDCVSEVEIIAE
PCRVEQDS-SDTMQTTGLLKGQGLTTLLSDLAKKKNPQ--KSSLSDQMDHPDFSSENPK-
IVDSSVNLHP-KQELLLMNSDDRDPPQHHSCLPDQE-VINGSLITGRQADSPMSTSSGSS
RSFSVASMLPETTREDVTSNAT-ANTCDSCTFVEQTDIVALAARAIFDQENLEKGRVGLQ
--ADIREVASKPSEASSLE--GDPPFKSQIPKENGTGQAEATPNEFNSQDSI---EATME
--RTLEKPSCSLG-IKTSNAPLQASASQPPSITSLSVNNLIHQSSISHPLASCAGLSPTS
EQTTVPATVNLTVSSSSYDSQPPG-PSLMTEYSQEQLNTMTST-IPNSQIQEPL-LKPSH
ESRKDSAKRAVQDDLLLSSAKRQKHCQPAPLRLESMSLMSRTPDTISDQTQMMVSQIPPN
SSNSVVS--VSNPAHGDGLTRLFPPSNNFVAPALRQTEVQCGSQPSVVAEQ--QQTQASQ
HLQALQQH--VPAQGVSHLHSNHLYIKQQQQQQQQQ-------QQQQQQQQAGQLRERHH
LYQM-QHHVPHAESSVHSQPHNVHQQRTLQQEVQMQKKRNLVQGTQASQLSLQPKHHGTD
QSRSKSGQPHPHHQQMQQQMQQHFGSSQTEKSCENPSTSRNHH-NHPQNHLNQDIMHQQ-
QDVGSRQQGSGVSSEHVSGHNPMQRLLTSRGLEQ-QMVSQPSIVTRSSDMTCTPHRPERN
RVSSYSAEALIGKTSSNSEQRMGISIQGSRVSDQLEMRSYLDVPRNKSLGIHNMQGRV--
DHTVASD-IRLSDCQTFKPSGASQQPQSNFEVQSSRNNEIGNP-VSSLRSMQSQAFRISQ
NTGPPPIDRQKRLPYPPVQSIPTGNGIPS-RDSENTCHQSFMQSLLAPHLSDQVIGSQRS
LSEHQRNAQCGPSSAIEYNCPPTHENVHIRRESDSQNRESCDMSLGAINTRNSTLNIPFS
SSSSSGDIQGRNTSPNVSVQKSNPMRITDSHATKGHMNPPVTTNMHGVARPALPHPSVSH
GNGDQGP-PVRQANSSVPQRSRHPLQDS-SGSKIRQPERNRSGNQRQSNVFDPSLPHLPL
STSGSMILGRQQPATEKRGSIVRFMPDSPQVPNDNSGPDQHTLSQNFGFSFIPEGGMNPP
INANASFIPQVTQPSATRTPALIPVDPQNTLPSFYPPYSPAHPTLSNDISIPYFPNQMFS
NPSTEKVNSGSLNNRFGSILSPPRPVGFAQPSFPLLPDMPPMHMTN-SHLSNFNMTSLFP
EIATAL-PDGSAMSPLLTIANSSASDSSKQSSNRPAHNISHILGHDCSSAV

----------------------MPEMTENETPTKKQHRKKNRETHNAVERHRKKKINAGI
NRIGELIPCSPALKQSKNMILDQAFKYITELKRQNDELLLNGGNNEQAEEIKKLRKQLEE
IQKENGRYIELLKANDICLYDDPTIHWKGNLKNSKVSVV---------------------
IPSDQIQKNIIVYSNGSQPGGNSQGAAVQGITFNVGHNLQKQTANVVPVQRACNLVTPVS
VSGVCPSENKPWHQTRVSAVAANQPLPLCLPATISAQNILELSTSESESSVLGATSGSL-
-IAVPVGPEPHQHCSFHTSLNDQSS---PENKNGQESPKLLKNTVPCALNVRSASSATTT
EVLPSSQ---PC-LSAQACRVELPGTL-VA----VTTAVCSQPPRPAGASS----PVGIS
QGTDLTNSATVVSLPVP-GVGKTATPVSTLSANPLDSGWTLSCSLPSSSVSTSDLKNINS
LTRISSAGNTQTTWTTLQLAGNTIQPLSQAPAVAVAPVLNESV--PSPTTTNHSRHVAAG
I--NSSNAFPADGQAGEQVVVTLPSCSSLPMQPLTAQPQVKPQPPKTILPLNSAMQVIQM
AQPVGSAVNAAPGNPNVIILQPPSTAPCPTVMRAEVPSQTVGQQIVIIQTA-NQNPVPLL
SAPPPGSVRLPVNGVNAIIGSNHSMQNASTPQTFGGKHLVHILPRPSSLS-TSSSTPTFS
VAMSNQQQPQTISLNGQLFALQPVMSSSGATNQTPMQIIQPTTSEDPNTNVALNTFGALA
SLNQSISQMAGQSCVQLSISQPANLQTAANSQATSANCVSLTTAVAPPVTADNSATLPSA
CDLATTPSVNSVACLPPNVKLKRLNKKPVAKKHLAA-SKSACSLNPVREVGKLGCPSTEG
SAELSCD-DVLLDSLPVDLP-SVAVSQAN---------SVNACGS-----HSLEVLNSE-
-----------------SVPKCKSTEESNSPSQEPVTSEHFATAPAKSKDSTPVLQPEIS
QDKPPTSLAFSDAAKSCPSANVLIPSPSDPQVLVSQVSGLSSTTNTASPDCVSEVEIVAE
PCRIEQDP-SDTMQTTGLLKGQGLTALLSDLAKEKDAQ--KTSLSVQADHPDFP-ENSK-
LADSSVDFHP-KQELLLLNGDGGDLPQHHSCIPGQE-VVSGSLLAGRQADSPMSTSSGSS
RSFSVASMLPEAAREDVTSSAP-ASTCDSCTFVEQTDIVALAARAIFDQENLEKGRVGIQ
--ADIREGTSKPSDTASLE--GDQPFKSQIPKENGTGQAEAVPNEFNSQDSV---EAAVD
--RPLEKPSCSVG-IKTSNASLQVSASQPPSITSLSVNNLIHQSGISHPLVSCAGLSQSS
EQTAVPATVNLTVASSSYGSQPPG-PSLMTEYAQGQLNTMTST-LPNSQIQEPL-LKPSH
ESRKDSAKRAVQDDLLLSSAKRQKHCQPAPLRLESMSLMSRTPDSISDQTQIMVSQIPPN
SSNSIVP--VSNPTHGDGLTRLFPPSNNFVAPALRQTELQCSSQPSV-AEQ--QPTQASQ
HLQALQQH--VPAQGVSHLHSNHLYLKQQQQ------------------QQVGQLRERHH
LYQL-QHHAPHAESTGHPQPHSVHQQRTLQQEVQMQKKRNLVQGTQASQLSLQPKHHGTD
QSRPKSGQPHPHHQQMQQQMQQQFGNSQPEKSCDNPSTSRNHH-NHPQNHLNQDIMHQQ-
QDVGSRQQGSGVSSEHVPGHNPMQRLLTSRGLEQ-QMVSQPSIVTRPSDMTCTPHRPERN
RVSSYSAEALIGKTSSNSEQRMALSIQGSRVSDQLEMRNYLDIPRNKNLAIHNMQSRV--
DHTLAPD-IRLPDCQTFKPSGASQQPQSNFEVQSSRNNEIGNP-VSSLRSMQSQTFRISQ
NSGPPAIDRQKRLPYPPVQSIPTGDAVPP-RDSDNTCHQSFMQSLLAPHLSDQVIGSQRS
LSEHQRNTQCGPSSAIEYNCPPAHESVHIRRESESQNRESCDMPLNAINTRNSTLNIPFS
SSSSSGDIQGRNTSPNVSVQKSNPMRITDSHGTKGHMNSPVTTNMHGIARPALPHPSVSH
GSADQGP-PVRQTNSSVPQRSRHPAQDS-SSSKIRQPERNRSGNQRHSNVFDPGLPHLPL
STSGSMILGRQQPTSEKRGSIVRFMPDSPQVPNDNSAPDQHTLSQNFGFSFIPEGGMNPP
INANTSFIPQVTQPSATRAPALIPVDPQNTLPSFYPPYSPAHPPLSNDISIPYFSNQMFS
NPSTEKVNSGSLNNRFGSILSPPRPVGFAQPSFPLLPDMPPMHMTN-SHLSNFNMTSLFP
EIATAL-PDGSAMSPLLTIANSSASDSSKQPSNRPAHNISHILGHDCSSAV

----------------------MPEMTENETPTKKQHRKKNRETHNAVERHRKKKINAGI
NRIGELIPCSPALKQSKNMILDQAFKYITELKRQNDELLLNGGNNEQAEEIKKLRKQLEE
IQKENGRYIELLKANDICLYDDPTIHWKGNLKNSKVSVV---------------------
IPSDQVQKNIIVYSNGNQPGGNSQGTAVQGITFNVSHNLQKQTANVVPVPRTCNLVTPVS
ISGVYPSENKPWHQTTVPTLATNQPVPLCLPATISAQSILELPTSESESSVLGATGGSL-
-IAVSIGPEPHQHHSLDTCLNDQNS---SENKNGQENPKLLKKMAPCATNIPLNSSATAT
EVHHGNK---SC-LSIRDFRGDVQNTFVVS----VTTTVCSQPPRTAGDSS----PVSIS
KSADSTSTATVVASSAP-GVGKATVPISTLSGNPLDNGWTLSCSLPSSSVSASDLKNINS
LTRISSAGNTQTTWTTLQLAGNTIQPLSQTPSSAVTPVLSESG--TSPTTSNHSRHLATG
I--NLNNSFPADGQPVEQVVVTLPSCPSLPMQPLIAQPQVKSQPPKNILPLNSAMQVIQM
AQPVGSAVNAAPTNQNVIILQPPSTTPCPAVMRAEVPNQTVGQQIVIIQAA-NQNPLPLL
SAPPPGSVRLPINGANAVIGSNNSVQNVSTPQTFGGKHLVHILPRPSSLS-MSNSTQTFS
VTMSS-QQPQTISLNGQLFALQPVMSSSGTTNQTPMQIIQPTTSEDPNTNVALNTFGALA
SLNQSISQMAGQSCVQLSISQPANTQTAANSQTTPANCVSLTTTAAPLVTTDSSATLAST
YNLVTTSSVNTVACLPPNMKSKRLNKKPGAKKHLAA-NKSACSLNPVRDVSKLDCPNTEG
SAEPPCN-DGLLESLPAVLP-SVSVSQAN---------SVSVSAS-----HSLGVVSSQS
-------------LIPESASKSKSAEKSSSPSQESVTSEHFAMAQAKSKDSTPNLQQEMS
QDKPPNSLALSDAAKPCTSANVLIPSPSDPHILVSQVSGLSSTTNTTSTDCVSEVEIIAE
PCRVEQDS-SDTMQTTGLLKGQGLTTLLSDLAKKKNPQ--KSSLSDQMDHPDFSSENPK-
IVDSSVNLHP-KQELLLMNNDERDPPQHHSCLPDQE-VIHGSLITGRQADSPMSTSSGSS
RSFSVASMLPETTREDVTSNAT-TNTCDSCTFVEQTDIVALAARAIFDQENLEKGRVGLQ
--TDIREVASKPSEASSLE--GDPPFKSQIPKENGTGQAEATPNEFNSQDST---EATME
--RPLEKPSCSLG-IKTSNASLQASNPQPPSITSLSVNNLIHQSSISHPLASCAGLSPTS
EQTTVPATVNLTISPSSYGSQPPG-PSLMTEYSQEQLNTMTST-IPNSQIQEPL-LKPSH
ESRKDSAKRAVQDDLLLSSAKRQKHCQPAPLRLESMSLMSRTPDTISDQTQMMVSQIPPN
SSNSAVP--VSNPAHGDGLTRLFPPTNNFVAPALRQAEVQCGSQPSV-AEQ--QQTQASQ
HLQALQQH--VPAQGVSHLHSNHLYIKQQQQQ---------------QQQQAGQLRERHH
LYQM-QHHVPHAESSVHSQPHNVHQQRTLQQEVQMQKKRNLVQGTQASQLSLQPKHHGTD
QSRSKSGQPHPHHQQLQQQMQQHFGSSQTEKSCENPSTTRNHH-NHPQNHLNQDIMHQQ-
QEVGSRQQGSGVSSEHVSGHNPMQRLLTSRGLEQ-QMVSQPSIVTRSSDMTCTPHRPERN
RVSSYSAEALIGKTSSNSEQRMGISIQGSRVSDQLEMRSYLDVPRNKSLAIHNMQGRV--
DHTVASD-IRLSDCQTFKPSGASQQPQSNFEVQSSRNNEIGNP-VSSLRSMQSQTFRISQ
NTGPPPIDRQKRLPYPPVQSIPTGNGIPS-RDSENTCHQSFMQSLLAPHLSDQVIGSQRS
LSEHQRNTQCGPSSAIEYNCPPTHENVHIRRESENQNRESCDMSLGAINTRNSTLNIPFS
SSSSSGDIQGRNTSPNVSVQKSNPMRITDSQAAKGHMNPPVTTNMHGVARPALPHPSVSH
GSADQGP-PVRQANSSVPQRSRHPLQDS-SGSKIRQPERNRSGNQRQSNVFDPSLPHLPL
STGGSMILGRQQPATEKRGSIVRFMPDSPQVPNDNSGPDQHTLSQNFGFSFIPEGGMNPP
INANASFIPQVTQPSATRTPALIPVDPQNTLPSFYPPYSPAHPTLSNDISIPYFSNQMFS
NPSTEKVNSGSLNNRFGSILSPPRPVGFAQPSFPLLPDMPPMHMTN-SHLSNFNMTSLFP
EIATAL-PDGSAMSPLLTIANSSASDSSKQSSNRPAHNISHILGHDCSSAV

----------------------MPEMTENETPTKKQHRKKNRETHNAVERHRKKKINAGI
NRIGELIPCSPALKQSKNMILDQAFKYITELKRQNDELLLNGGNNEQAEEIKKLRKQLEE
IQKENGRYIELLKANDICLYDDPTIHWKGNLKNSKVSVV---------------------
IPSDQVQKNIIVYSNGNQPGGNSQGTAVQGITFNVSHNLQKQTANVVPVQRTCNLVTPVS
ISGVYPSENKPWHQTTVPALATNQPVPLCLPAAISAQSILELPTSESESNVLGATSGSL-
-IAVSIGSEPHQHHSLHTCLNDQNS---FENKNGQENPKLLKKMTPCVTNIPHSSSATAT
KVHHGNK---SC-LSIQDFRGDFQNTFVVS----VNTTVCSQPPRTADDSS----PMIIS
KSADLTSTATVVASSAP-GVGKATIPVSTLSGNPLDNGWTLSCSLPSSSVSTSDLKNINS
LTRISSAGNTQTTWTTLQLAGNTIQPLSQTPSSAVTPVLNESG--TSPTTSNHSRHVATG
I--NLNNSFPADGQPVEQVVVTLPSCPSLPMQPLIAQPQVKSQPPKNILPLNSAMQVIQM
AQPVGSAVNAAPANQNVIILQPPSTTPCPTVMRAEVPNQTVGQQIVIIQAA-NQNPLPLL
PAPPPGSVRLPINGANTVIGSNNSVQNVPTPQTFGGKHLVHILPRPSSLS-ASSSTQTFS
VTMSN-QQPQTISLNGQLFALQPVMSSSGTTNQTPMQIIQPTTSEDPNTNVALNTFGALA
SLNQSISQMAGQSCVQLSISQPANAQTAANSQTTTANCVSLTTTAAPPVTTDSSATLAST
YNLVSTSSMNTVACLP-NMKSKRLNKKPGARKHLAA-NKSACPLNSVRDVSKLDCPNTEG
SAEPSCN-DGLLESFPAVLP-SVSMSQAN---------SVSVSAS-----HSLGVLSSES
-------------LIPESVSKSKSAEKSSPPSQESVMSEHFAMATAKSKDSTPNLQQETS
QDKPPSSLALSDAAKPCTSANVLIPSPSDPHILVSQVSGLSSTTSTTSTDCVSEVEIIAE
PCRVEQDS-SDTMQTTGLLKGQGLTTLLSDLAKKKNPQ--KSSLSDQMDHPDFSSENPK-
IVDSSVNLHP-KQELLLMNNDDRDPPQHHSCLPDQE-VINGSLITGRQADSPMSTSSGSS
RSFSVASMLPETTREDVTSNAT-TNTCDSCTFVEQTDIVALAARAIFDQENLEKGRVGLQ
--ADIREVASKPSEASLLE--GHPPFKSQIPKENGTGQAEATSNEFNSQGSI---EATVE
--RTLEKPSCSLG-IKTSNASLQDSTSQPPSITSLSVNNLIHQSSISHPLASCAGLSPTS
EQTTVPATVNLTISSSSYGSQPPG-PSLMTEYSQEQLNTMTST-IPNSQIQEPL-LKPSH
ESRKDSAKRAVQDDLLLSSAKRQKHCQPAPLRLESMSLMSRTPDTISDQTQIMVSQIPPN
SSNSVVP--VSNPAHGDGLTRLFPPSNNFVAPALRQTEVQCGSQPSV-AEQ--QQTQASQ
HLQALQQH--VPAQGVSHLHSNHLYIKQQQQQ-------------QQQQQQAGQLRERHH
LYQM-QHHVPHAESSVHSQPHNVHQQRTLQQEVQMQKKRNLVQGTQTSQLSLQPKHHGTD
QSRSKSGQPHPHHQQMQQQMQQHFGSSQTEKSCENPSTSRNHH-NHPQNHLNQDIMHQQ-
QEVGSRQQGSGVSSEHVSGHNPMQRLLTSRGLEQ-QIVSQPSIVTRSSDMTCTPHRPERN
RVSSYSAEALIGKTSSNSEQRMGISIQGSRVSDQLEMRSYLDVPRNKSLAIHNMQGRV--
DHTVASD-IRLSDCQTFKPSGASQQPQSNFEVQSSRNNEIGNP-VSSLRSMQSQAFRISQ
NTGPPPIDRQKRLPYPPVQSIPTGNGIPS-RDSENTCHQSFMQSLLAPHLSDQVIGSQRS
LSEHQRNTQCGTSSAIEYNCPPTHENVHIRRESESQNRESCDMSLGAINARNSTLNIPFS
SSSSSGDIQGRNTSPNVSVQKSNPMRITDSHATKGHMNPPVTTNMHGVARPALPHPSVSH
GNGDQGP-AVRQANSSVPQRSRHPLQDS-SGSKIRQPERNRSGNQRQSTVFDPSLPHLPL
STGGSMILGRQQPATEKRGSIVRFMPDSPQVPNDNSGPDQHTLSQNFGFSFIPEGGMNPP
INANASFIPQVTQPSATRTPALIPVDPQNTLPSFYPPYSPAHPTLSNDISIPYFPNQMFS
NPSTEKVNSGSLNNRFGSILSPPRPVGFAQPSFPLLPDMPPMHMTN-SHLSNFNMTSLFP
EIATAL-PDGSAMSPLLTIANSSASDSSKQSSNRPAHNISHILGHDCSSAV

----------------------MPEMTECETPTKKQHRKKNRETHNAVERHRKKKINAGI
NRIGELIPCSPALKQSKNMILDQAFKYITELKRQNDELLLNGGNNEQAEEIKKLRKQLEE
IQKENGRYIELLKANDICLYDDPTIHWKGNLKNSKVSVV---------------------
IPSDQVQKNIIVYSNGSQPGGNSQGTAVQGITFNVGHNLQKQTANVVPVQRTCNLLTPVS
VSGIYPSEKKPWHQTTVSALAANQPVPLCLPAAISAQNILELSTSESESSVFGATGGSL-
-IAVSVGPEPLQHPSSHIYPNDQNS---SENNHGLDSTKILKKTAPCVTSVPPSSSVTTT
KVHHGTK---SC-LNLQNCRGDFQNTFIVS----VTTTICSQPPRSIGDSS----PLSVS
KCTDSTNTTTVVAPSAP-SVGKITTPVSILSTNPLDSNWALSCSLPSSSASASDLKNINS
LTRISSAGNTQTTWTTLQLAGNTIQPLSQTPSSTVTPVLSESS--TSPTTRNHSRPVATG
I--NLNNSLPADGQPVEQVVVTLPSCPPLPMQPLISQSQVKSQPPKNILPLNSAMQVIQM
AQSVGSAVNAASASQNVIILQPPSTTPCPTVMRAEVPNQTVGQQIVIIQAA-NQNPLPLL
SAPPSGSVRLPVNGASAIIGSNNSVQNVSTPQTFGGKHLVHILPRPSSLS-TSNSTQTFS
VTMSNQQQPQTISLNGQLFTLQPVMSSSGTTNQTPMQIIQPTTSEDPNTNVALNTFGALA
SLNQSISQMAGQSCVQLSVNQPANPQTAVSSQSTSANCVSLT-SIAPSTTTDSSATITST
YNLVTTSSVNTVACLPPTTKSKRLNKKPGAKKHLAA-GKPACPLTPVREVGKLDGPRTEG
SAESPCN-DGLLESLPIVLP-SVTVSETN--------I-------SVSASHSLDILNSES
-------------VIPESIPKSKSAE--VSPHQESVASEHSVAAPEKSKDSMSILQQETS
QDKPPTSLALSDATKPCTSASVLILSPSEPQVLASQVSGLSSSTSTTSSDCVSEVEIVAE
PCRVEQDS-SDTIQAAGLLKGQGLTTLLSDLAKEKDPQ--KSSLSVQIDHPDFSSENSK-
VVNSSVDLHP-KQELLLMNNEDRDPPQQHSCLPDQE-VMNGSLL-TRQADSPMSTSSGSS
RSFSVASMLPETTREDVTSS-T-TNTCDSCTFVEQTDIVALAARAIFDQENSEKGRAGIQ
--ADIREITSKSSEASSLE--GDQTFKSH-PKENGTGQAETTPNEFNSQDSI---EVTVD
--RPLEKPSCSVG-IKTSNTSLQASTSQPPTLTSLSVNNLIHQSSITHPLVSCAGLSQTS
DQTAVPTTVNLTVSSSSYSSQPPG-PSLMTEYSQEQLNTMAST-IPNSQIQEPL-LKPNH
ENRKDSAKRAVQDDLLLSSAKRQKHCQPVPLRLENMTLMSRTPDGISDQAQMMVSQIPPN
SSNSVVP--VSNPAHGDGLTRLFPPGNNFVAPALRQTEVQCSSQPSV-AEQ--QQTQASQ
HLQALQQH--VPPQGVSHLHSNHLYIKQQQQ------------------QQAGQLRERHH
LYQL-QHHVPHTENAVHSQPHNVHQQRTLQQEVQMQKKRNLVQGAQGSQLSLQPKHHATD
QSRPKSGQPHPHHQQMQQQMQQHFGSSQPEKSCENPSTSRNHH-SHPQNHLNQDIMHQQ-
QDVGSRPQGSGVSSEHVSGHNPMQRLLTSRGLEQ-QMVSQPSIVTRSSDMTCTPHRTERN
RVSSYSAEALIGKTSSNSEQRMGISIQGSRVSDQLEMRSYLDVPRNKSLAIHNMQSHV--
DHTVASD-IRLSDCQTFKPSGASQQPQSNFEVQSSRNNEIGNA-VSSLRSMQSQAFRISQ
NTGPPPIDRQKRLPYPPVQSIPTGNAVPP-RDSENTCHQSFMQSLLAPHLGDQVIGSQRS
LSEHQRNTQCGPSSAIEYNCPPTHDSVHIRRDSESQNRESCDMSLGAINTRNSTLNIPFS
SSSSSGDIQGRNTSPNVSIQKSNPMRITDSHGTKGHMNPPVTTNMHGVARPALPHLSVSH
GNADQGP-PVRQANTSVPQRSRPALQDS-GSSKIRQPERNRSGNQRHSNVFDPSLPHLPL
STSGSMILGRQQPATEKRGSIVRFMPDGPQVPNDNSGPDQHSLSQNFGFPFIPEGGMNPP
INANTSFIPQVTQPSATRTPALIPVDPQNTLPSFYPPYSPAHPTLSNDISIPYFSNQMFS
NPTTEKVNSGSLNNRFGSILSPPRPVGFAQPSFPLLPDMPPMHMTN-SHLSNFNMTSLFP
EIATAL-PDGSAMSPLLTIANSSASDSSKQSSNRPAHNISHILGHDCSSAV

----------------------MPEMTENETPTKKQHRKKNRETHNAVERHRKKKINAGI
NRIGELIPCSPALKQSKNMILDQAFKYITELKRQNDELLLNGGNNEQAEEIKKLRKQLEE
IQKENGRYIELLKANDICLYDDPTIHWKGNLKNSKVSVV---------------------
IPSDQVQKNIIVYSNGNQPGGNSQGTAVQGITFNVSHNLQKQTANVVPVQRTCNLVTPIS
ISGVYPSENKPWHQTTVPALATNQPVPLCLPAAISAQSVLELPTSESESSVLGASSGSL-
-IAVSVGPEPHQHHSLHTCLNDQNS---SENKNGQENPKLLKKMTPCAVNIPLSSSATAT
KVHHGNK---SC-LSIQDFRGDFQNTFVVS----VTTTVCSQPPRTADDSS----PMSIS
KSADLTSTATVVASSAP-GVGKATIPISTLSGNPLDNGWTLSCSLPSSSVSTSDLKNINS
LTRISSAGNTQTTWTTLQLAGNTIQPLSQTPSSAVTPVLNESG--TSPTTSNHSRHVATG
I--NLNNSFPADGQPVEQVVVTLPSCPSLPMQPLIAQPQVKSQPPKNILPLNSAMQVIQM
AQPVGSAVNATPTNQNVIILQPPSTTPCPTVMRAEVPNHTVGQQIVIIQAA-NQNPLPLL
SAPPPGSVRLPINGANTVIGSNNSVQNVSTPQTFGGKHLVHILPRPSSLS-VSNSTQTFS
VTMSN-QQPQTISLNGQLFALQPVMSSSGTTNQTPMQIIQPTTSEDPNTNVALNTFGALA
SLNQSISQMAGQSCVQLSISQPANAQTAANSQTTTANCVSLAT-AAPPVTTDSSATLAST
YNLVSTSSMNTVACLPPNMKSKRLNKKPGARKHLAA-NKSACPLNPVRDVSKLDCPNTES
SAELPCN-DGLLESFPAVLP-PVSMSQAN---------SVSVSAS-----HSLGVLNSES
-------------LIPESVSKSKSIEKSSSPSQESVTSEHFAMAPAKSKDSTPNLQQETP
QDKPPSHLALSDAAEPCTSANVLIPSPSDPHILVSQVSGLSSTTSTTSTDCVSEVEIIAE
PCRVEQDS-SDTMQTTGLLKGQGLTTLLSDLAKKKNPQ--KSSLSDQMDHPDFSSENPK-
IVDSSVNLHP-KQELLLMNSDDRDPPQHHSCLPDQE-VINGSLITSRQADSPMSTSSGSS
RSFSVASMLPETTREDVTSNAT-ANTCDSCTFVEQTDIVALAARAIFDQENLEKGRVGLQ
--ADIREVASKPSEASSLE--GDPPFKSQIPKENGTGQAEATPNEFNSQDSI---EATME
--RPLEKPSCSLG-IKTSNAPLQASPSQPPSITSLSVNNLIHQSSISHPLASCAGLSPTS
EQTTVPATVNLTVSSSSYDSQPPG-PSLMTEYSQEQLNTMTST-IPNSQIQEPL-LKPSH
ESRKDSAKRAVQDDLLLSSAKRQKHCQPAPLRLESMSLMSRTPDTISDQTQMMVSQIPPN
SSNSVVP--VSNPAHGDGLTRLFPPSNNFVAPALRQTEVHCGSQPSV-AEQ--QQTQASQ
HLQALQQH--VPAQGVSHLHSNHLYIKQQQQQQQ----------QQQQQQQAGQLRERHH
LYQM-QHHVPHAESSVHSQPHNVHQQRTLQQEVQMQKKRNLVQGTQASQLSLQPKHHGTD
QSRSKSGQPHPHHQQMQQQMQQHFGSSQTEKSCENPSTSRNHH-NHPQNHLNQDIMHQQ-
QDVGSRQQGSGVSSEHVSGHNPMQRLLTSRGLEQ-QMVSQPSIVTRSSDMTCTPHRPERN
RVSSYSAEALIGKTSSNSEQRMGISIQGSRVSDQLEMRSYLDVPRNKSLAIHNMQGRV--
DHTVASD-IRLSDCQTFKPSGASQQPQSNFEVQSSRNNEIGNP-VSSLRSMQSQAFRISQ
NTGPPPIDRQKRLPYPPVQSIPTGNGIPS-RDSENTCHQSFMQSLLAPHLSDQVIGSQRS
LSEHQRNTQCGPSSAIEYNCPPTHENVHIRRESDSQNRESCDMSLGAINTRNSTLNIPFS
SSSSSGDIQGRNTSPNVSVQKSNPMRITDSHATKGHMNPPVTTNMHGVARPALPHPSVSH
GNGDQGP-PVRQANSSVPQRSRHPLQDS-SGSKIRQPERNRSGNQRQSNVFDPSLPHLPL
STGGSMILGRQQPATEKRGSIVRFMPDSPQVPNDNSGPDQHTLSQNFGFSFIPEGGMNPP
INANASFIPQVTQPSATRTPALIPVDPQNTLPSFYPPYSPAHPTLSNDISIPYFPNQMFS
NPSTEKVNSGSLNNRFGSILSPPRPVGFAQPSFPLLPDMPPMHMTN-SHLSNFNMTSLFP
EIATAL-PDGSAMSPLLTIANSSASDSSKQSSNRPAHNISHILGHDCSSAV

----------------------MPEMTENETPTKKQHRKKNRETHNAVERHRKKKINAGI
NRIGELIPCSPALKQSKNMILDQAFKYITELKRQNDELLLNGGNNEQAEEIKKLRKQLEE
IQKENGRYIELLKANDICLYDDPTIHWKGNLKSSKVSVV---------------------
IPSDQVQKNIIVYSNGSQPGGNSQGTAVQGITFNVGHNLQKQTANVVPVQRTCNLVTPVS
ISGVYPSENKPWHQTTVSALAANQPVPLCLPATISAQNILELSTSESESSVPGATSGSL-
-IAVPIGPEPHQHRSLHTCLNEQNS---PENKSGHESPKLVKKTGPCATSIPTTSSATAA
KAHHGSK---SC-LSIQDFRSDFQTTFVVS----VTTTVCSQPPRSAGDSC----PVSIS
KGADLAGVTAVVAPSAP-GGGKTTTPVSTLSATPLENSWTLSCSLPSSSVSASDLKSMNS
LTRISSTGNTQTTWTTLHLAGNTVQPLSQTPSSAVTPVVNESG--TSPPTTNHSRHVTTG
V--NLNNSFPADGQAVEQVVVTLPSCPSLPMQPLIAHPQVKSQPPKNILPLNSAMQVIQM
AQPVGSAVNAAPANQNVIILQPPSTTPCPTVMRAEVPNQTVGQQIVIIQAA-NQNPLPLL
SAPPSGSVRLPVNGANALIGSNNSVQNVSTPQTFGGKHLVHILPRPSSLS-TSSSTQTFS
VTMSNQQQPQTISLNGQLFALQPVMSSSGTTNQTPMQIIQPTTSEDPNTNVALNTFGALA
SLNQSISQMAGQSCVQLSISQPANPPTAANSQTAPVNCVSLTTTVASAMTTDNSATLPST
YNLVTTPSMNTVACLP-NVKSKRLNKKPGTKKHLAA-NKSACPLNPVREAGKLDCPSTEV
T--SCNN-DGLLESLPVVLP-SVTMSQAN---------SVSVSGS-----HSLDVLNSES
-------------VIPESVPKSKSAEETSSPSQEPVTSEHFVMAPAKSKDSIPILQRETS
QDKPPTSLALSDAAKSCTSANVLIPSPTDPHILVSQVSGLSSTTSTASTDCVSEVEIIAE
PCRAEQDA-SDTMQTTGLLKGQGLTALLSGLAKEKDPQ--KLSLSVQVDHPDFSSENSK-
IVDSGVDLHP-KQEVLLMNSDDRDPGPPHSCVPDQE-VISGSLLVSRQADSPMSTSSGSS
RSFSVASMLPETTREDVTSSTT-TNTCDSCTFVEQTDIVALAARAIFDQDNLEKGRAGSQ
--ADMREVTSKPSEASPLE--GDQPFKTQISKEGGAGQAEVTPNEFNSQDSI---EATVD
--RPLGKPSCSIG-IKTSNASLQVSTSQPPSITSLSVNNLIHQSSISHPLVSCAGLSQTS
EQTTVPATVNLTVASSSYATQPPG-PALMTEYPQEQLNTIPGT-IPNPQIQEPL-LKPSQ
ESRKDSAKRAVQDDLLLSSAKRQKHCQPAPLRLEAMSLMSRTPDSISDQAQMIVSQLPPN
SANSVVP--LSNPAHGDGLTRLFPPSNNFVAPALRQVEVQCSSQNSV-AEQ--QQTQASQ
HLQALQQH--VPAQGVSHLHSNHLYVKQQQQ------------------QQAGQLRERHH
LYQL-QHHVPHAESSVHSQPHNVHQQRTLQQEVQMQKKRNLVQGTQTSQLSLQPKHHGTD
QSRPKSGQPHPHHQQMQQQMQQHFGSSQPEKSCENPSTSRNHH-NHPQNHLNQDIMHQQ-
PDVGSRQQGSGVSSEHVSGHNPMQRLLTSRGIEQ-QMVSQPSIVTRPSDMTCTPHRPERN
RVSSYSAEALIGKTSSNSEQRMGISIQGSRVSDQLEMRSYLDVPRNKSLAIHNMQGRV--
DHTVTSD-IRLSDCQTFKPSGASQQPPSNFEVQSSRNNEIGNP-VSSLRSMQTQAFRISQ
NPGPPPIDRQKRLPYPPVQSIPTGNAIPP-RDSENTCHQSFMQSLLAPHLGDQVLGSQRS
LSEHQRNTQCGPSSAIEYNCPPTHESVHIRRESESQNRESCDMSLGAINSRNSTLNIPFS
SSSSSGDIQGRNTSPNVSVQKSNPMRITDSHGTKGHMNPPVTTNMHGVARPALPHPSVSH
GNAEQGP-PVRPTNSSVPQRSRHPLQDS-SGSKIRQPERNRSGNQRHSNVFDPSLPHLPL
STSGSMILGRQQPTTEKRGSIVRFMPDSPQVPNDNSAPDQHTLSQNFSFPFIPEGGMNPP
INANTSFIPQVTQPSATRTPALIPVDPQNTLPSFYPPYSPAHPTLSNDISIPYFSNQMFS
NPSTEKVNSGSLNNRFGSILSPPRPVGFAQPSFPLLPEMPPMHMTN-SHLSNFNMTSLFP
EIATAL-PDGSAMSPLLTIANSSASDSSKQSSNRPAHNISHILGHDCSSAV

----------------------MPEMTENEMPTKKQHRKKNRETHNAVERHRKKKINAGI
NRIGELIPCSPALKQSKNMILDQAFKYITELKRQNDELLLNGGNNEQAEEIKKLRKQLEE
IQKENGRYIELLKANDICLYDDPTIHWKGNLKNSKVSVV---------------------
IPSDQVQKNIIVYSNGNQPGGNSQGTAVQGITFNVSHNLQKQTANVVPVPRTCNLVTPVS
ISGVYPSENKPWHQTTVPALATNQPVPLCLPATISAQSILELPTSESESSVLGATGGSL-
-IAVSIGPEPHQHRSLHTCLNDQNS---SENKNGQENPKLLKKMAPCATNIPLNSSATAT
EVHHGNK---SC-LSIQDFRGDVQNTFVVS----VTTTVCSQPPRTAGDSS----PVSIS
KSADLTSTATVVASSAP-GVGKATVPISTLSGNPLDNGWTLSCSLPSSSVSASDLKNINS
LTRISSAGNTQTTWTTLQLAGNTIQPLSQTPSSAVTPVLSESG--TSPTTSNHSRHMATG
I--NLNNSFPADGQPVEQVVVTLPSCPSLPMQPLIAQPQVKSQPPKNILPLNSAMQVIQM
AQPVGSAVNAAPTNQNVIILQPPSTTPCPTVMRAEVPNQTVGQQIVIIQAA-NQNPLPLL
SAPPPGSVRLPINGANAVIGSNNSAQNVSTPQTFGGKHLVHILPRPSSLS-MSNSTQTFS
VTMSS-QQPQTISLNGQLFALQPVMSSSGTTNQTPMQIIQPTTSEDPNTNVALNTFGALA
SLNQSISQMAGQSCVQLSISQPANTQTAANSQTTPANCVSLTTTAAPLVTTDSSATLAST
YNLVTTSSVNTVACLPPNMKSKRLNKKPGAKKHLAA-NKLACSLNPVRDVSKLDCPNTEG
SAEPPCN-EGLLESLPVVLP-SVSMSQAN---------SVSVSAS-----HSLGVVSSES
-------------LIPESASKSKSAEKSSSPSQESVTSEHFAMAPEKSKDSTPNLPQEMS
QDKPPSSLALSDAAKPCTSANVLIPSASDPHILVSQVSGLSSTTSTTSTDCVSEVEIIAE
PCRVEQDS-SDTMQTTGLLKGQGLTTLLSDLAKKKNPQ--KSSLSDQMDHPDFSSENPK-
IVDSSVNLQP-KQELLLMNNDERDPPQHHSCLPDQE-VIHGSLITGRQADSPMSTSSGSS
RSFSVASMLPETTREDVTSNAT-TNTCDSCTFVEQTDIVALAARAIFDQENLEKGRVGLQ
--ADIREVASKPSEVSSLE--GDPPFKSQIPKENGTGQAEATPNEFNSQDSI---EATME
--RPLEKPSCSLG-IKTSNASLQASNPQPPSITSLSVNNLIHQSSISHPLASCAGLSPTS
EQTTVPATVNLTISSSSYGSQPPG-PSLMTEYSQEQLNTMTST-IRNSQIQEPL-LKPSH
ESRKDSAKRAVQDDLLLSSAKRQKHCQPAPLRLESMSLMSRTPDTISDQTQMMVSQLPPN
SSNSVVP--VSNPAHGDGLTRLFPSANNFVAPALRQTEVQCGSQPSV-AEQ--QQTQANQ
HLQALQQH--VPAQGVSHLHSNHLYIKQQQ------------------QQQAGQLRERHH
LYQM-QHHIPHAESSVHSQPHNVHQQRTLQQEVQMQKKRNLVQGTQASQLSLQPKHHGTD
QSRSKSGQPHPHHQQLQQQIQQHFGSSQTEKSCENPSTTRNHH-NHPQNHLNQDIMHQQ-
QEVGSRQQGSGVSSEHVSGHNPMQRLLTSRGLEQ-QMVSQPSIVTRSSDMTCTPHRPERN
RVSSYSAEALIGKTSSNSEQRMGISIQGSRVSDQLEMRSYLDVPRNKSLAIHNMQGRV--
DHTVTSD-IRLSDCQTFKPSGASQQPQSNFEVQSSRNNEIGNP-VSSLRSMQSQAFRISQ
NTGPPPTDRQKRLPYPPVQNIPTGNGIPS-RDSENTCHQSFMQSLLAPHLSDQVIGSQRS
LSEHQRNTQCGPSSAIEYNCPPTHENVHIRRESESQNRESCDMSLGAINTRNSTLNIPFS
SSSSSGDIQGRNTSPNVSVQKSNPMRITDSQATKGHMNPPVTTNMHGVARPALPHPSVSH
GNADQGP-PVRQANSSVPQRSRHPLQDS-SGSKIRQPERNRSGNQRQSNVFDPSLPHLPL
STGGSMILGRQQPATEKRGSIVRFMPDSPQVPNDNSGPDQHTLSQNFGFSFIPEGGMNPP
INANASFIPQVTQPSATRTPALIPVDPQNTLPSFYPPYSPAHPTLSNDISIPYFSNQMFS
NPSTEKVNSGSLNNRFGSILSPPRPVGFAQPSFPLLPDMPPMHMTN-SHLSNFNMTSLFP
EIATAL-PDGSAMSPLLTIANSSASDSSKQSSNRPAHNISHILGHDCSSAV

----------------------MPEMTENETPTKKQHRKKNRETHNAVERHRKKKINAGI
NRIGELIPCSPALKQSKNMILDQAFKYITELKRQNDELLLNGGNNEQAEEIKKLRKQLEE
IQKENGRYIELLKANDICLYDDPTIHWKGNLKNSKVSVV---------------------
IPSDQVQKNIIVYSNGSQPGGNSQGTAVQGITFNVGHNLQKQTANVVPVQRTCNLVTPVS
ISGVYPSENKPWHQTTVSALAANQPVPLCLPAALSAQNILELSTSESESSVLGPTSSSL-
-IAVPVGPEPPQHHSSHTCLNDQNS---SENKKGQESPQVLKKTVPCATSISSSCSATAT
QGQPGSE---SC-LSAQDHRSDLQTTLVVS----ITTTVCSQPPRPVGDSC----VASSS
KGADSASVTMVVAPSVP-GGGMTTMPVSTLSANPMDSGWTLSCSLPSSAVSASDLKNMNS
LTRISSAGNTQTTWTTLQLAGNTIQPLSQTPSSAVTPVLNESG--TSPTTANHSRCVAPG
I--SLNNSFPAEGQPVEQVVVTLPSCPPLPMQPLITQPQVKSQPPKSILPLNSAMQVIQM
AQPVGSAVNASPANQNVIILQPPSTTPCPTVMRAEVPNQTVGQQIVIIQAA-NQNTLPLL
SAPPPGSVRLPVNGASAIIGSNNSVQNVSTPQTFGGKHLVHILPRPTSLS-ASNSTQTFS
VTVSSQQQPQTISLNGQLFALQPVMSSSGTTNQTPMQIIQPTTSEDPNTNVALNTFGALA
SLNQSISQMAGQSCVQLSVSQPVHPQTAGNSQITPANCISLT-TVAPPVTTDNSATPPSA
YNLVTTPSVNTVACLP-NTKAKRLNKKPGVKKHLAT-NKSACSLNLVRDGGKSDGPSTEG
SAEPSCN-DGLLESLPGVLP-SAIVSQTN---------SVSISGS-----HSLNVLNSES
-------------VMPESVPKSKSAEESSSPSQESVTSEQFTMAPAKSKDFLPISQRETS
QDKPPSSLALPEAAKSCTSASVLISSANDAPVLASQVSHLSSATSTTSTDCVSEVEVIAD
PCRAEQES-SDTVQTAGLLKEQGLTALLSGLAKEKDPQ--KSSLSVQVDHPDFSSENSK-
IVDSNVELHP-KQELLLMNSDDRDPGQPHSCIPDQE-VINGSLLTSRQADSPMSTSSGSS
RSFSVASMLPETAREDVTSSAT-TNTCDSCTFVEQTDIVALAARAIFDQENLEKGRGGTQ
VPADIREVPSKPSEASSLE--GDQPFKTQIPKENGPGQVEATPNEFNSQDSI---EATVD
--RPLEKPSCSIG-MKTSNASLQVSTSQPPSITSLSVNNLIHQSTLSHPLVSCTGLSQTS
GQTAVPTTVNLTVSSGSYGSQPPG-PSLMTEYSQEQLNTMAGT-IPNTPIPEPL-LKPSH
ESRKDSAKRAVQDDLLLSSAKRQKHCQPAPLRLEGLSLMSRTPDSISDQTQMMVGQIPPN
SSNSVVP--ISNPAHGDGLTRLFPPSNNFVVPALRQTEVQCSSQASI-AEQ--QPAQAGQ
HLQALQQH--VPAQGVPHLHSNHLYLKQQ--------------------QQAGQLRERHH
LYQL-QRHVPHAESSVHSQPHSVHQQRTLQQEVQMQKKRNLVQGTQASQLSLQPKHHGTD
QSRPKSGQPHPHHQQMQQQVQQHFGTSQAEKGCENPSTSRNHQ-N----HLSQDILHQ--
QEVGSRQQAPGVSSEHVSGHNPMQRLLTSRGIEQ-QMASQSSIVTRPSDMTCAPHRPERN
RVSSYSAEALIGKTSSNSEQRMGISIQGSRVSDQLEMRSYLDVPRNKSLAIHNMQGRV--
DHT-ASD-IRLSDCQTFKPSGASQQPQNNFEVQSSRNNEIGNP-VSSLRSMQPQAFRIGQ
NPGPPPVDRQKRLPYPPAQSIPTGNAIPT-RDSENTCHQSFMQSLLAPHLGDQVIGSQRS
LSEHQRNTQCGPSSAIEYNCPPSHESVHIRRESESQSRESCDMSLGAINTRNSTLNIPFS
SSSSSGDIQGRNTSPNVSVQKSNPMRITDSHGAKGHMNPPVTTNMHGVVRPALPHPSASH
GNADQGP-PVRQTSSSVPQRSRHPLQDS-SGSKIRPPERTRSGNPRHSNVFDPSLPHLPL
STGGSMILGRQQPAAEKRGSIVRFMPDSPQVPNDNSVPDQHTLSQNFGFPFIPEGGMNPP
INANASFIPQVTQPSATRTPALIPVDPQNTLPSFYPPYSPAHPTLSNDISIPYFSNQMFS
NPSTEKVNSGSLNNRFGSILSPPRPVGFAQPSFPLLPDMPPMHMTN-SHLSNFNMTSLFP
EIATAL-PDGSAMSPLLTIANSSASDSSKQSSNRPAHNISHILGHDCSSAV

MVPAVGLQLTSAPSTPILLSQAMPEMTEK-APLKKQHRKKNRETHNAVERHRKKKINAGI
NKIGELIPCSPALKQSKNMILDQAYKYITEMKRQNDELLLNGGNNEQAEEIKKLRKQLDE
LQKENGRFIALLKANDICLYDDPTIHWKGNLKNAKVSVVIPNDQGQKKKGNLKSANISVV
IPNDQLQKNIIVYSNGSQLNGSNQGASIQGITFNISPNLQKQTANVVPVQRTCNLVTPVS
IY---STEMKSGSQFSVSPLAPA--------MSNPAKEILEHSASENEQNVSVCTTASSV
NVLPVMRIQPEMP----SSAQEEDI---SKSKNRQESFGTIEHVGVPNSILPSNATVNL-
--SHSQ--LAET-ASKEDSGNGPLESCSIS----TPEVICTPLVYEKPPTEK---KISIS
E----APAADILK----PGIETHTLPATTL------SKW----PFPSSSVGSPGSKGLGG
LARITSAGNTQTTWTTLQLTGNTVQPVNHTLPNIMTALLNEPVSDANTIAPTPSRILATT
T--GFNNLQPAEEQTAEQIMAALPSYPSLPMQPLVTKAQVVAQPAGGLLSLNSAMQVIQM
PQPVGPPVAVPPANQNVVILQPPNASPCPPVLRTDLPNQTVSQQIVIIQTA-NPNPLSLF
SAPPPA--RMPMNGASLLTNVGNSMQNSSSPQMFGGKHLVHILPRPSSSSPSSGLTQTVS
VAMSNQQLPQTISLNGQLFALKPVKSCSGNSDQIPMQIIQPTTSEDPNTNVALNTFGALA
NLNQSISQMAGQSCLKGSAYQPVNPSAV-SSQSTPSKPVLLPSATVPSSTSESSVLISVS
HSEE-TVPQK----SSLRLSAKCSNKNPSTRKCSMSGNNLACQMNSSKDSKKLNNVNADA
PCENSVS-DSLLENIPANALQNFVLPQTD--------GRISSNDANASESQSKEGLRVEQ
HVESVLSPDLNATVMPQSLPLVSSS-----------SGQFEGVVPVSTVCDSPPLQTCTV
QTHSVTSSELSESSK-CISNSPLPSSSSISHLTVSQTSVTSVTNGGISAEKI-PRTDVSD
ICRAEQNC-SIVMQATDLLEEQGLTKILSDFSKVGEVVEKNF----SVEHTGFCTQGTKS
ILDSSDELTGKEEGLLLMNTEEENLAQTHSCPSEQE-TVA----ANRQADSPMSTSSGSS
CGFSVASMLPGTCRESVPNSTL-VNTCNNCTFSEQTDIVALAARAIFDQETLIKETRTPA
------------SKANDVG--REQSLKSHITK--NVDQIEIAPNNFNTQNSNAQNSVQVN
NDRSAEKQSCSIE-VEMSNTALQIPTPQSSSTSSLSVNNLIHQTCIIHPAVSCSSLPSPS
NQAAVPVTQSMPVNSYMNQSPGQS-PALMTEYASEQLSALQTSTMQAPLLREPQLKQQGQ
GSRKESAKRAVQDDHLLSSSKRQKQCQTAPLQLEDMGLLHQTSDDIVDQNQILVNQIPNS
SNL-A--VTVNSQGHTDGHSRLFPS-SNFVSPALRQAEVQCNSQPSVSD-------QAGQ
HLPTVQ-H--TPAQSLAHLHSNHPYIKQQQQQ-----------------QQAGQLRERHQ
LYQL-QHHISHTETSIHSQAHITHQQRVMHQEVQMQKKRTLIQAAHPTTHPLQQKHHGND
Q-RSKTSQPHSHHSQLQ-QMQQHYASSQSEKSCENPTTNRSHH-SHPQSHLNQDILHQQS
PDVGNRQSGSGVSSEHVPGHSQIQRLMTSRALEQ-QMVSQPSIVTRPSDMACVPHRQERN
RVSSYSAEALIGKSPSNSEQRLGISIQSTRAPEHLEMRNFLDVSRNKGLAIHNMQGRMSV
EHTVGPDVQRLSECQTFKTNGTNQQSTSNFDVQSSRNSEIGNS-MPTLRAMQTQAFRIAQ
NAGL-PLDRQKRLPYQPVQGISSGNALPPSRDNENTCHQGFMQSLLVPHLGDQSSGSQRP
ISEHQRNSQCASASNVEYNCSPARDSIHIRREGDGQNRESCDMTLVTINSRNNSLNIPFS
S---SGDIQGRNSSPNISAQKSNPMRMTESHGTKGHMNAPVSSNVHGIIRSPLQHPPVSR
GNADQVPPSIRQPNSSATQRSRHPLQDG--SSKVRQPERNRSGNQRHGGMFDPSLPHLPL
AASSSMILGRQQPTLEKRSSIVRFMSEGAQVSNESAVPDQQSLSQNFGFSFIPENGMNPP
INANTSFIPPVTQSSATRTPALIPVDPQNTLPSFYPPYSPAHPSLSNDISLPYFSNQMFS
NPSTEKPSGGTLNNRFGSILSPPRPVGFAQPSFPLLTDMPPMHMANSSHLSNFNLTSLFP
EIATALPSDGSAISPLLSITNT-ASDTSKQSSNRPAHNISHILGHDCSSAV

----------------------MPEMTEHETPTKKQHRKKNRETHNAVERHRKKKINAGI
NRIGELIPCSPALKQSKNMILDQAFKYITELKRQNDELLLNGGNSEQAEEIKKLRKQLEE
IQKENGRYIELLKANDICLYDDPTIHWKGNLKNSKVSVV---------------------
IPSDQVQKNIIVYSNGSQPGGNSQGTAVQGITFNVGHSLQKQTANVVPVQRTCKLVTPVS
ISGVYPSENKPWHQNTVSALAANQPVPLCLPTAISAQNILELSTSESQSSVLGATGGSL-
-ITVSVGPEPHQHHSLHTCLIDQNA---SENSNGQESPKS-KKTVACVTSISSSSSAPAS
KEHHETQ---SG-PSVQSSSGDLQNTIVVS----VTTTVCSEPPRSTGESS----PVSIS
KTADSTTTTTVVAPVHT-GVAKTTLPVSSLSAKPLDNGWTLSCSLPSSSVSASDLKNINS
LTRISSAGNTQTTWTTLHLAGNTIQPLSQTPSSAVTPVLNESGTS---PTPSHHKHVSTG
I--TLSNSLPADGQPVEQIVVTLPSCPPLPMQPPIAQPQVKSQPPKNILPLNSAMQVIQM
AQPVGSAVTAAPGNQNVIILQPPSTTPCPTMLRAEVPNQTVGQQIVIIQAA-NQNPLPLL
SAPHPGPVRLPVNGASAIIGSHNSVQSVPAPQTFGGKHLVHILPRPSSLS-TTNSTQTFS
VTMSNQQQPQTISLNGQLFALQPVMSSSGTTNQTPMQIIQPTTSEDPNTNVALNTFGALA
SLNQSISQMAGQSCVQLSISQSANPQTSANSQTSPANCASLTTTVAPTMTTDNLATLPST
YSLAAASSTNTITCLPPTMKSKRLNKKPGAKKHLAV-NKPACPLNSVRDVGKLDGPRTDS
STELSCS-DGQLDSLPVNLP-SVAVSQAK--------S------VSISTSHSLDILNSES
-------------VIPESVSKSKSVEDCSSSSQESETNEQFAVAPAKSKDSTPILQ-ETS
QGTPPTTVALSSATKSCTSTHVLIPSPIESQILVSQVSGMSSTTSTSSTDCISEVEIVAE
PCPVQQDS-LNNMQTAGPLKGQGLTMLLSDLTKEKDLQ--KSSLSVQIDHPDFSPENSK-
IGDSNVDMHP-KQELLLMN-DDRDPPQHHSCLPDQE-VLNGSLLTSRQADSPMSTSSGSS
RSFSVASMLPETAREDVTSSTT-TNTCDSCTFAEQTDIVALAARAILDQENIDKGRVGTQ
--TEMREVTSKPSET-SLE--GEQPFKPQLHKEPCTGQADATPNEFNSQDSV---EVTVD
--RPLEKPSCSLG-IKTSNASLQVSASQPPSLTSLSVNNLIHQSSINHPLVSCTGLSQTS
EQTSIPVTVNMTVASSSYGSQPPV-PPLMTEYSQEQLNSMTSA-IPNPQIQEPL-SKPSH
EGRKDSTKRTVQDDLLLSSAKRQKHCQAAPLRLESLPLMSRTPDSIPDQTQMMASQIPTN
SSNSVVP--ASNPAHGDSLTRLFPPGNNFAAPALRQTEVQCSSQPPVAEQQ--QQTQASQ
HLQALQQH--VPTQGVSHLHTNHLYIKQQQQQ-----------------QQAGQLRERHH
LYQL-QHHVPHADSAVHSQPHIVHQQRTLQQEVQMQKKRNLVQGAPASQLSLQPKHHGTD
QSRPKSSQPHPHHQQIQQQIQQHFANSQPEKSCENPSTSRGHH-NHAQNHLNQDILHQQ-
QDVGSRQQGSAVSSDHVSGHNQMQRLLPTRGLEQ-QMVSQPSIVTRSSDMTCTPHRPERN
RVSSYSAEALIGKSSSTSEQRMGMSIQGSRVSEQLEMRSYLDVPRNKSLALHNMQGRM--
DHT-----VPLPDCQTFKPAGASQQPQSNFEVQSSRNNEIGNP-VPSLRSMQSQAFRISQ
NTGPPPIDRQKRLPYPPVQSIPTGNAVPP-RDNENTCHQSFMQSLLAPHLGDQVIGSQRS
LSEHPRNTQCGPSSTIEYNCPPTRESVHIRRESENQNRESCDMSLGTINTRNSTLNIPFS
SSSSSGDIQGRNTSPNVSVQKSNPMRITDSHGTKSHMNPPVTSNMHGVARPTLPHPSVSH
GNADQGP-PVRQANSSVAQRSRHPLQDS-TGSKIRQPERNRSGNQRHSNVFDPSLPHLPL
SAGGSMILGRQQPATEKRGSIVRFMPDSPQVPNDNSGPDQHTLSQNFGFPFIPEGGMNPP
INANTSFIPQVTQPSATRTPALIPVDPQNTLPSFYPPYSPAHPTLSNDISIPYFSNQMFS
NPSTEKVNSGSLNNRFGSILSPPRPVGFAQPSFPLLPEMPPMHMAN-SHLSNFNMTSLFP
EIATAL-PDGSAMSPLLTIANSSASDSSKQSSNRPAHNISHILGHDCSSAV

----------------------MPEMTEHETPTKKQHRKKNRETHNAVERHRKKKINAGI
NRIGELIPCSPALKQSKNMILDQAFKYITELKRQNDELLLNGGSSEQAEEIKKLRKQLEE
IQKENGRYIELLKANDICLYDDPTIHWKGSLKTSKVSVV---------------------
IPSDQVQKNIIVYSNGSQPAGNSPGTAVQGITFNVGHGLHKQTANVVPVQRTCKLVTPVS
ISGVYPSENKPWHQTTVSALTANQSVPLCLPAAISAQNILELSTSESQSSVLGATGGSV-
-VTVSVGPDPHPHCSLNTCLNDQSA---SENNNAQESPKSSKKTVTCGSGTSSSNSAAVP
DVHHETK---SS-PSMQGFSADSQSAL-VS----VTTTVCSQPPRSTGGSS----PVSGS
KTADSS-AATAVVPAHA-AAAKSALPVSSLSANPLEGGWTLSCSLPSSSVSASELKNINS
LTRISSAGNTQTTWTTLHLAGNTIQPLSQPPPSAATPALNECGTSP---TPNNHKHVATG
I--TLNNSLPTDGQPVEQVVVTLPSCPPLPMQPLIAQPQVKSQPPKNILPLNSAMQVIQM
AQPVGSGVTAAPANQNVIILQPPSTTPCPTMMRAEVSNQTVGQQIVIIQAA-NQNPLPLL
SAPHPGPVRLPVNGASAIIGSHNSVQNVPAPQTFGGKHLVHILPRPSSLS-TSNSTQTFS
VTMANQQQPQTISLNGQLFALQPVMSSSGTTNQSPMQIIQPTTSEDPNTNVALNTFGALA
SLNQSISQMAGQSCVQLSISQSANPQTSANSQTSPANCVSLTATVAPTITADNSATPSTT
YSLATASSANIVTCLPSTMKSKRLSKKPGAKKHLTA-NKPACPLNSVRDVGKIDSPRINS
SAEPSCS-DGLLDSLPVGLS-SVAVSQAK--------N------VRISASHSLDVLNSES
-------------VIPDSDPKSKSAEDCSSPSQESETNEQLVLAPAKPKDSTPILQ-ETS
QGTPPCSVALSNDTKSCTSANVLSPSPMESQSLVSQVSGLSSTTSTSSTDCISEVEIVAE
PCPVQQAS-LDTMQTAGPLKGQGLTMLLSDLAKEKDLQ--RSSLSVQMEHPDFSPESSK-
IGDSNVDLHP-KQELLLL-SDDRDPPQPHSCLPDQE-VLHGSLLTSRQADSPLSTSSGSS
RSFSVASMLPETAREDVTSSTT-SNTCDGCTFAEQTDIVALAARAILGQDNIEKGRLGTQ
--ADVKEVTPKPSET-SLE--GDQPFKPQIHKESCTGQADPTPNEFNSQDSV---EVTVD
--RPLEKPSCSLG-IKGSNAPIQVSASEPPSLTHQ-------NSI-SHPLVSCTGLSQSS
DQTSNPVTVNMTVSSSSYDSQPPV-PPLMTEYPQEQLNSMTSA-IPNPQVQEPL-SKPSH
ESRKDSAKRTVQDDLLLSSAKRQKHCQPAPLRLESMPLISRTPDNIPDPTQMMASQITPN
SSNSVVP--VSNPAHGDGLARLFPPSNNFVAPALRQTDVQCNSQPSVAEQQQQQQTQAGQ
HLQALQQH--VPPQGVSHLHTNHLYIKQQQQQQQQ---------QQQQQQQAGQLRERHH
LYQL-QHHVPHADSAVHSQPHIVHQQRTLQQEVQMQKKRNLVQGTPTSQLSLQPKHHGTD
QSRPKSSQPHPHHQQMQQQLQQHFASSQPEKSCENPSTSRGHH-SHPQNHLNQDVLHQQ-
QDVGSRQQG----SDHVSGHNPMQRLLPSRGLEQ-QMVSQPSIVTRSSDMTCAPHRSERN
RVSSYSAEALIGKSSSTSEQRMGISVQGSRVSDQLEMRSYLDVPRNKSLALHNMQGRM--
DHTVTSD-IRLSDCQTFKPGGASQQPQSNFEVQSSRNNEIGNP-VPSLRSMQSQAFRISQ
NTGLPPIDRQKRLSYPPVQSIPTGNAVPP-RDSENTCHQSFMQSLLAPHLGDQVIGSQRS
LSEHPRNTQCGPSSTIEYNCPPTRESVHIRRESESQNRESCDMSLGAVNPRNSTLNIPFS
SSSSSGDIQGRNTSPNVSVQKSNPMRITDSHGAKGHMNPPVTSNMHGVARPTLPHPSVSH
GNADQGP-PVRQANSSVAQRSRHPLQDS-SGSKIRQPERNRSGNQRHSNVFDPSLPHLPL
STGGSMILGRQQPAAEKRGSIVRFMPDSPQVPNDNSGPDQHSLSQNFGFPFIPEGGMNPP
INANTSFIPQVTQPSATRAPALIPVDPQNTLPSFYPPYSPAHPTLSNDISIPYFSNQMFS
NPSTEKVNSGSLNNRFGSILSPPRPVGFAQPSFPLLPEMPPMHMAN-SHLSNFNMTSLFP
EIAAAL-PDGSAMSPLLTIANSSAPDSSKQPSNRPAHNISHILGHDCSSAV

----------------------MPEMTEHETPTKKQHRKKNRETHNAVERHRKKKINAGI
SRIGELIPCSPALKQSKNMILDQAFKYITELKRQNDELLLNGGNNEQGKDLELLAVC---
------------------LCLGVRVTVKVILEHRR---L---------------------
LPPKQN------------------------------------------------------
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----------------------MPEMTENETPTKKQHRKKNRETHNAVERHRKKKINAGI
NRIGELIPCSPALKQSKNMILDQAFKYITELKRQNDELLLNGGNNEQAEEIKKLRKQLEE
IQKENGRYIELLKANDICLYDDPTIHWKGNLKNSKVSVV---------------------
IPSDQVQKNIIVYSNGNQPGGNSQGTAVQGITFNVSHNLQKQTANVVPVQRTCNLVTPIS
ISGVYPSENKPWHQTTVPALATNQPVPLCLPAAISAQSVLELPTSESESSVLGASSGSL-
-IAVSVGPEPHQHHSLHTCLNDQNS---SENKNGQENPKLLKKMTPCAVNIPLSSSATAT
KVHHGNK---SC-LSIQDFRGDFQNTFVVS----VTTTVCSQPPRTADDSS----PMSIS
KRADLTSTATVVASCAP-GVGKATIPISTLSGNPLDNGWTLSCSLPSSSVSTSDLKNINS
LTRISSAGNTQTTWTTLQLAGNTIQPLSQTPSSAVTPVLNESG--TNPTTSNHSRHVATG
I--NLNNSFPADGQPVEQVVVTLPSCPSLPMQPLIAQPQVKSQPPKNILPLNSAMQVIQM
AQPVGSAVNAAPTNQNVIILQPPSTTPCPTVMRAEVPNHTVGQQIVIIQAA-NQNPLPLL
SAPPPGSVRLPINGANTVIGSNNSVQNVSTPQTFGGKHLVHILPRPSSLS-VSNSTQTFS
VTMSN-QQPQTISLNGQLFALQPVMSSSGTTNQTPMQIIQPTTSEDPNTNVALNTFGALA
SLNQSISQMAGQSCVQLSISQPANAQTAANSQTTTANCVSLAT-AAPPVTTDSSATLAST
YNLVSTSSMNTVACLPPNMKSKRLNKKPGARKHLAA-NKSACPLNPVRDVSKLDCPNTES
SAELPCN-DGLLESFPAVLP-PVSMSQAN---------SVSVSAS-----HSLGVLNSES
-------------LIPESVSKSKSIEKSSSPSQESVTSEHFAMAPAKSKDSTPNLQQETP
QDKPPSHLALSDAAKPCTSADVLIPSPSDPHILVSQVSGLSSTTSTTSTDCVSEVEIIAE
PCRVEQDS-SDTMQTTGLLKGQGLTTLLSDLAKKKNPQ--KSSLSDQMDHPDFSSENPK-
IVDSSVNLHP-KQELLLMNSDDRDPPQHHSCLPDQE-VINGSLITSRQADSPMSTSSGSS
RSFSVASMLPETTREDVTSNAT-ANTCDSCTFVEQTDIVALAARAIFDQENLEKGRVGLQ
--ADIREVASKPSEASSLE--GDPPFKSQIPKENGTGQAEATPNEFNSQDSI---EATME
--RPLEKPSCSLG-IKTSNAPLQASPSQPPSITSLSVNNLIHQSSISHPLASCAGLSPTS
EQTTVPATVNLTVSSSSYDSQPPG-PSLMTEYSQEQLNTMTSS-IPNSQIQEPL-LKPSH
ESRKDSAKRAVQDDLLLSSAKRQKHCQPAPLRLESMSLMSRTPDTISDQTQMMVSQIPPN
SSNSVVP--VSNPAHGDGLTRLFPPSNNFVAPALRQTEVHCGSQPSV-AEQ--QQTQASQ
HLQALQQH--VPAQGVSHLHSNHLYIKQQQQQQ-----------QQQQQQQAGQLRERHH
LYQM-QHHVPHAESSVHSQPHNVHQQRTLQQEVQMQKKRNLVQGTQASQLSLQPKHHGTD
QSRSKSGQPHPHHQQMQQQMQQHFGSSQTEKSCENPSTSRNHH-NHPQNHLNQDIMHQQ-
QDVGSRQQGSGVSSEHVSGHNPMQRLLTSRGLEQ-QMVSQPSIVTRSSDMTCTPHRPERN
RVSSYSAEALIGKTSSNSEQRMGISIQGSRVSDQLEMRSYLDVPRNKSLAIHNMQGRV--
DHTVASD-IRLSDCQTFKPSGASQQPQSNFEVQSSRNNEIGNP-VSSLRSMQSQAFRISQ
NTGPPPIDRQKRLPYPPVQSIPTGNGIPS-RDSENTCHQSFMQSLLAPHLSDQVIGSQRS
LSEHQRNTQCGPSSAIEYNCPPTHENVHIRRESDSQNRESCDMSLGAINTRNSTLNIPFS
SSSSSGDIQGRNTSPNVSVQKSNPMRITDSHATKGHMNPPVTTNMHGVARPALPHPSVSH
GNGDQGP-PVRQANSSVPQRSRHPLQDS-SGSKIRQPERNRSGNQRQSNVFDPSLPHLPL
SSGGSMILGRQQPATEKRGSIVRFMPDSPQVPNDNSGPDQHTLSQNFGFSFIPEGGMNPP
INANASFIPQVTQPSATRTPALIPVDPQNTLPSFYPPYSPAHPTLSNDISIPYFPNQMFS
NPSTEKVNSGSLNNRFGSILSPPRPVGFAQPSFPLLPDMPPMHMTN-SHLSNFNMTSLFP
EIATAL-PDGSAMSPLLTIANSSASDSSKQSSNRPAHNISHILGHDCSSAV

----------------------MPEMTENETPTKKQHRKKNRETHNAVERHRKKKINAGI
NRIGELIPCSPALKQSKNMILDQAFKYITELKRQNDELLLNGGNNEQXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---------------------
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-
-XXXXXXXXXXXXXXXXXXXXXXXX---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXX---XX-XXXXXXXXXXXXXXXXX----XXXXXXXXXXXXXXXXX----XXXXX
XXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXX
X--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXX
XXXXXXX-XXXXXXXXXXXX-XXXXXXXX---------XXXXXXX-----XXXXXXXXXX
-------------XXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTSSTDCN--KKVIAE
PCRAEQDP-SDTVQTTGLLKGQGLTALLSGLAKEKDPQ--KSSLSVQVDPPDFSSGNSK-
IVDSNVDLHP-KQELLLMNSDDRDPGQHHSCIPDQE-VINGSLL-SRQADSPMSTSSGSS
RSFSVASMLPETTREDVTSNAT-TNTCDSCTFVEQTDIVALAARAIFDQENLEKGRAGTQ
--ADIREVTSKSSEASSLE--GDQPFKTQISKENGPGQAEATPNEFHSQDSV---EATVD
--RPLEKPSCSIG-IKTSNAALQVSTSQPPSITSLSVNNLIHQSSISHPLVSCAGLSQTS
EQATVPATVNLTVSSSSYGSQPPG-PSLMTEYSQEQLNTMAGT-LPNPQIQESL-LKPSH
ENRKDSAKRAVQDDLLLSSAKRQKHCQPAPLRLEGLSLMSRTPDSISEQTQMMIGQIPPN
SSNSVVP--ISNPAHGDGLTRLFPPGNNFVAPALRQNEVQCSSQPSV-AEQ--QQTQASQ
HLQALQQH--VPAQGVPHLHSNHLYLKQQQQQQ--------------QQQQAGQLRERHH
LYQL-QHHVPHAESSVHSQPHSVHQQRALQQEVQMQKKRNLVQGTQTSQLALQPKHHGND
QSRPKSGQPHPHHQQMQQQMQQHFGSSQPEKSCENPSTSRNHH-NHPQNHLNQDIMHQQ-
QDVGSRPQGSGVSSEHVPGHNPMQRLLTSRGIEQ-QMVSQPSIVTRPSDMTCTPHRPERN
RVSSYSAEALIGKTSSNSEQRMGISIQGSRVSDQLEMRSYLDVPRNKSLAIHNMQGRV--
DHTVASD-IRLSDCQTFKPSGASQQPQSNFEVQSSRNNEIGNP-VSSLRSMQSQAFRISQ
NPGPPPIDRQKRLPYPPVQSIPTGNAIPP-RDSENTCHQSFMQSLLAPHLGDQVIGSQRS
LSEHQRNTQCGPPSAIEYNCPPTHESVHIRREGESQNRESCDMSLGAINTRNSTLNIPFS
SSSSSGDIQGRNTSPNVSVQKSNPMRITDSHGTKGHMNPPVTSNMHGVARPALPHPSVSH
GNADQGP-PVRQTNSSVPQRSRHPLQDS-SGSKIRQPERNRSGNQRHSNVFDPSLPHLPL
STSGSMILGRQQPTAEKRGSIVRFMPDSPQVPNDNSAPEWDPLXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXIPYFS--MFS
NPSTEKVNSGTLNNRFGSILSPPRPVGFAQPSFPLLPDMPPMHMTN-SHLSNFNMTSLFP
EIATAL-PDGSAMSPLLTIANSSASDSSKQSSNRPAHNISHILGHDCSSAV

----------------------MPEMTENETPTKKQHRKKNRETHNAVERHRKKKINAGI
NRIGELIPCSPALKQSKNMILDQAFKYITELKRQNDELLLNGGNNEQAEEIKKLRKQLEE
IQKENGRYIELLKANDICLYDDPTIHWKGNLKNSKVSVV---------------------
IPTDQIQKNIIVYSNGSQPGGNSQGTAVQGITFNVGHNLQKQTANVMPVQRTCNLVTPVS
ISGVYPSENKPWHQTTVAALAANQPVPLCLPATISAPSILELSTSESESSVLGATSGSL-
-IAVPVGPEPHQHCSFHPSLNDQHP---SETKNDQESPKLLKKMVPCTTSLPSSSSVTAT
KVQHGSK---PC-PSIQECRSDFQNTFVVA----VAATVCSQLPRSVDDPS----PLNSG
KGTDSTSGSTVVVPSTS-DVRKTVTPVSTLSANSLDSGWTLSCSLPSSSVSASDLKNINS
LTRISSAGNTQTTWTTLQLTGNTIQPLSQTPSTAVTPVLNESG--TSPTAVNHSRHVATG
I--NLNNSFPADGQPVEQVVVTLPSCPSLPMQPLIAQPQVKSQPPKNILPLNSAMQVIQM
AQPVGTAINAAPANPNVIILQPPSTTPCPTVVRAEVPNQTVGQQIVIIQAA-NQNALPLL
SAPPPGSVRLPVNGASAVIGSNNSVQNISTPQTFGGKHLVHILPRPSSLS-TSNSTQTFS
VTMSNQQQPQTISLNGQLFALQPVMSSSGTTNQTPMQIIQPTTSEDPNTNVALNTFGALA
SLNQSISQMAGQSCVQLSITQPANPQTAANSQITPANCVSLT-TVAPPVIADNSATLPST
YNLVTTSSTNPVAYLPPNVKSKRLSKKPGAKKHITA-NKSACPLNPTRDMGKLDCPSTEG
SAEPSCN-DEMLENLPVVLP-SVAMSQAN--------N---VSVS-----GTLEVLNSES
-------------VISESVSKSKSAEESSLCSQELMTSEPFAVAPAKSKDPTPILHQETS
QDKPPPSLALSDAATSSTSANMLIPSPNDTHILVSQVSGLSSTTSSTNTNCVSEVEIIAE
PCRAEQDS-SDTTQTTGLLKGQGLTALLSDLAKEKDPK--KTSLPVQVDHPDFSSENSK-
IVDSSVDLHP-KQELLLINSDGRDPPQHHSCLSDQE-VINGSLLTSRQSDSPMSTSSGSS
RSFSVASMLPETTREDVTSSTT-TNTCDNCTFVEQT------------------------
--------XSKPSEPSSLE--GDQPFKTQIPKENGTGQPEATPNEFNSQISM---EATVD
--RPLEKPSCSIG-IKTSNSSLQVPSSQPPTITSLSVNNLIHQSSISHPLVSCAGLSQSS
EQTTVPATVNLTVSPSSYGSQPPG-PSLMTDYSQEQLTTMTST-IPNSQIQEPL-LKPSH
ESRKDSAKRAVQDDLLLSSTKRQKHCQPAPHRLENMSLMSRTPDSISDQTQMMVGQMPPN
SSNSVVP--VTNPAHGDGLTRLFPPNNNFVAPALRQTEVQCTSQPTV-AEQ--QQTQASQ
HLQALQQH--VSTQGVSHLHSNHLYLKQQQQQ---------------QQQQAGQLRERHH
LYQL-QHHVPHAESSVHSQTHNVHQQRTLQQEVQMQKKRNLVQGAQASQLSLQPKHHGTD
QSRPKSGQPHPHHQQMQQQMQQHFGSSQPEKSCENPSTSRNHH-NHPQNHLNQDIMHQQ-
QDVGSRQQGSGVSSEHISGHNTMQRLLTSRGLEQ-QMVSQPSIVTRPSDMTCTPHRSERN
RVSSYSAEALIGKTSSNSEQRMGISIQGSRVSDQLEMRSYLDVPRNKSLVVHNMQGHV--
DHTVASD-IRLSDCQTFKPGGASQQPQSNFEVQSSRNNEIGNP-ISSLRSMQSQAFRISQ
NPGL-PIDRQKRLPYPPVQNIPTGNSVPP-RDGENTCHQSFMQSLLAPHLSDQVIGSQRS
LSELQRNTQCGPSSTIEYNCPPAHESVHIRRESESQNRESCDMSLSTVNTRNSTLSIPFS
SSSSSGDIQGRNTSPNVSVQKSNPMRITDSHGTKGHMNPPVTTNMHGVARPALPHPSVSH
GNADQGP-PVRQANSLVPQRSRHPLQDS-SGSKIRQPERNRSGNQRHSNVFDPSLPHLPL
STSGSMILGRQQPTTEKRGSIVRFMPDSPQVPNENSAPDQHTLSQNFGFPFIPEGSMNPP
INANTSFIPQVTQPSATRTPALIPVDPQNTLPSFYPPYSPAHPTLSNDISIPYFSNQMFS
NPSTEKVNSGSLNNRFGSILSPPRPVGFAQPSFPLLPDMPPMHMTN-SHLSNFNMTSLFP
EIATAL-PDGSAMSPLLTIANSSASDSSKQSSNRPAHNISHILGHDCSSAV

----------------------MPEMTENETPTKKQHRKKNRETHNAVERHRKKKINAGI
NRIGELIPCSPALKQSKNMILDQAFKYITELKRQNDELLLNGGNNEQAEEIKKLRKQLEE
IQKENGRYIELLKANDICLYDDPTIHWKGNLKNSKVSVV---------------------
IPSDQVQKNIIVYSNGNQPGGNSQGTAVQGITFNVSHNLQKQTANVVPVQRTCNLVTPIS
ISGVYPSENKPWHQTTVPALATNQPVPLCLPAAISAQSILELPTSESESSVLGASSGSL-
-IAVSVGPEPHQHHSLHTCLNDQNS---SENKNGQENPKLLKKMTPCAINIPLSSSATAT
KVHHGNK---SC-LSIQDFRGDFQNTFVVS----VTTTVCSQPSGTADDSS----PMSIS
KSADLTSTATVVASSAP-GVGKATIPISTLSGNPLDNGWTLSCSLPSSSVSTSDLKNINS
LTRISSAGNTQTTWTTLQLAGNTIQPLSQTPSSAVTPVLNESG--TSPTTSNHSRHVATG
I--NLNNSFPADGQPVEQVVVTLPSCPSLPMQPLIAQPQVKSQPPKNILPLNSAMQVIHM
AQPVGSAVNAAPTNQNVIILQPPSTTPCPTVMRAEVPNQTVGQQIVIIQAA-NQNPLPLL
SAPPPGSVRLPINGANTVIGSNNSVQNVSTPQTFGGKHLVHILPRPSSLS-VSNSTQTFS
VTMSN-QQPQTISLNGQLFALQPVMSSSGTTNQTPMQIIQPTTSEDPNTNVALNTFGALA
SLNQSISQMAGQSCVQLSISQPANAQTAANSQTTTANCVSLAT-AAPPVTTDSSATLAST
YNLVSTSSMNTVACLPPNMKSKRLNKKPGARKHLAA-NKSACPLNPVRDVSKLDCPNTEG
SAEPPCN-DGLLESFPAVLP-SVSMSQAN---------SVSVSAS-----HSLGVLNSES
-------------LIPESVSKSKSTEKSSSPSQESVTSEHFAMAPAKSKDSTPNLQQETP
QDKPPSSLALSDAAKPCTSANVLIPSPSDPHILVSQVSGLSSTTSTTSTDCVSEVEIIAE
PCRVEQDS-SDTMQTTGLLKGQGLTTLLSDLAKKKNPQ--KSSLSDQMDHPDFSSENPK-
IVDSSVNLHP-KQELLLMNSDDRDPPQHHSCLPDQE-VINGSLITGRQADSPMSTSSGSS
RSFSVASMLPETTREDVTSNAT-ANTCDSCTFVEQTDIVALAARAIFDQENLEKGRVGLQ
--ADIREVASKPSEASSLE--GDPPFKSQIPKENGTGQAEATPNEFNSQDSI---EATME
--RPLEKPSCSLG-IKTSNAPLQASASQPPSITSLSVNNLIHQSSISHPLASCAGLSPTS
EQTTVPATVNLTVSSSSYDSQPPG-PSLMTEYSQEQLNTMTST-IPNSQIQEPL-LKPSH
ESRKDSAKRAVQDDLLLSSAKRQKHCQPAPLRLESMSLMSRTPDTISDQTQMMVSQIPPN
SSNSVVS--VSNPAHGDGLTRLFPPSNNFVAPALRQTEVQCGSQPSVVAEQ--QQTQASQ
HLQALQQH--VPAQGVSHLHSNHLYIKQQQQQQQQQQQ---QQQQQQQQQQAGQLRERHH
LYQM-QHHVPHAESSVHSQPHNVHQQRTLQQEVQMQKKRNLVQGTQASQLSLQPKHHGTD
QSRSKSGQPHPHHQQMQQQMQQHFGSSQTEKSCENPSTSRNHH-NHPQNHLNQDIMHQQ-
QDVGSRQQGSGVSSEHVSGHNPMQRLLTSRGLEQ-QMVSQPSIVTRSSDMTCTPHRPERN
RVSSYSAEALIGKTSSNSEQRMGISIQGSRVSDQLEMRSYLDVPRNKSLGIHNMQGRV--
DHTVASD-IRLSDCQTFKPSGASQQPQSNFEVQSSRNNEIGNP-VSSLRSMQSQAFRISQ
NTGPPPIDRQKRLPYPPVQSIPTGNGIPS-RDSENTCHQSFMQSLLAPHLSDQVIGSQRS
LSEHQRNAQCGPSSAIEYNCPPTHENVHIRRESDSQNRESCDMSLGAINTRNSTLNIPFS
SSSSSGDIQGRNTSPNVSVQKSNPMRITDSHATKGHMNPPVTTNMHGVARPALPHPSVSH
GNGDQGP-PVRQANSSVPQRSRHPLQDS-SGSKIRQPERNRSGNQRQSNVFDPSLPHLPL
STSGSMILGRQQPATEKRGSIVRFMPDSPQVPNDNSGPDQHTLSQNFGFSFIPEGGMNPP
INANASFIPQVTQPSATRTPALIPVDPQNTLPSFYPPYSPAHPTLSNDISIPYFPNQMFS
NPSTEKVNSGSLNNRFGSILSPPRPVGFAQPSFPLLPDMPPMHMTN-SHLSNFNMTSLFP
EIATAL-PDGSAMSPLLTIANSSASDSSKQSSNRPAHNISHILGHDCSSAV

----------------------MPEMTEHETPTKKQHRKKNRETHNAVERHRKKKINAGI
NRIGELIPCSPALKQSKNMILDQAFKYITELKRQNDELLLNGGNSEQGRCVESCCLLFV-
LQ----------------------------------------------------------
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----------------------MPEMTENETPTKKQHRKKNRETHNAVERHRKKKINAGI
NRIGELIPCSPALKQSKNMILDQAFKYITELKRQNDELLLNGGNNEQAEEIKKLRKQLEE
IQKENGRYIELLKANDICLYDDPTIHWKGNLKNSKVSVV---------------------
IPSDQVQKNIIVYSSGSQPGGNSQGTAVQGITFNVGHNLQKQTANVVPVQRTCNLVTPVS
ISGVYPPENKPWHQTTVSALATNQ--PLCLPATISAQNILELSTSESESNVLGATSSSL-
-ITVPVGPEPHQHCSLNTFLNDQNS---SENKNGQESPKLLKKTAPCATGIPPNSSAAAT
KVRHGNK---SC-LSIQDFRGDFQNTFVVS----VTTTVCSQPPRSAGDSS----PVSTS
KSAGSTSTTTVVAPSAP-GIGKTTTLVSTLSANPLDNGWTLLCSLPSSSVSASDLKNINS
LTRISSAGNTQTTWTTLQLAGNTIQPLSQTPSSTVTPVLNESG--TSPTTSNHNRHVAAG
I--NLSNSFPADGQPAEQVVVTLPSCPSLPMQPLIAQPQVKSQPPKNILPLNSTMQVIHM
AQPVGPAVNAAPANQNVIILQPPSTTPCPTVMRAEVPNQTVGQQIVIIQAA-NQNPLPLL
SAPPAGSVRLPVNGANAIIGSNNSVQNVSTPQTFGGKHLVHILPRPSSLS-PSNSTQTFS
VTMSNQQQPQTISLNGQLFALQPVMSSSGTTNQTPMQIIQPTTSEDPNTNIALNTFGALA
SLNQSISQMAGQSCVQLSISQPANPPTTTNSQTTPANCVSLTTTVAPPMTTENSATLPST
YNLVTTPSVNTVACLPPNVKSKRLNRKPGAKKHLAA-NKSACPLNPVRDVSKLDCPSAEG
SAEPPCN-DGLLESLPVVLP-SVPVSQAN---------SVSVSAS-----HSLDVLNSES
-------------VIPESVSKSKSSEESRSPSQENVTSEHFAMAPAKSKDSTPNLQRETS
QDKPPTSLALSDAAKSCTSANALIPSPNDPHILVSQVSGLSSTTSTTSTDCVSEVEIIAE
PCRVEQES-SDTMQTTGLLKGQGLNALLSDLAKEKDPQ--KSSLSNQMDHPEFSSENSK-
IVDSSVNLHP-KQELLLMNNDDRDPPQHHSCLPDQE-VINGSLLTSRQADSPMSTSSGSS
RSFSVASMLPETTREDVTSNAT-TNTCDSCTFAEQTDIVALAARAIFDQENLEKGRVGLQ
--TDVREVTSKPSEASSLE--GDPAFKSQTSKESGTGQAEATANEFNSQDSI---EATVD
--RSLEKPSCSLG-IKTSNASLQASPSQPPSITSLSVNNLIHQSSISHPLVSCAGLAQTS
EQTTVPATVNLTVSPSSYGSQPPG-PSLMTEYSQEQLNTMTST-IPNSQIQEPL-LKPSH
ESRKDSAKRAVQDDLLLSSAKRQKHCQPAPLRLESMSLMSRTPDSISDQTQMMVSQIPPN
SSNSVVP--VSNPAHGDGLARLFPPGNNFVAPALRQTEVQCSSQPSV-AEQ--QQTQASQ
HLQALQQH--VPAQGVSHLHSNHLYIKQQQQ----------------QQQQAGQLRERHH
LYQL-QHHVPHADSSVHSQPHNVHQQRTLQQEVQMQKKRNLVQGSQASQLSLQPKHHGTD
QSRPKSGQPHPHHQQMQQQMQQHFGNSQPEKSCENPSTSRNHH-NHPQNHLNQDIMHQQ-
QDVGSRQQGSGVSSEHVSGHNPMQRLLTSRGLEQ-QMVSQPSIVTRPSDMTCTPHRTERN
RVSSYSAEALIGKTSSNSEQRMGISIQGSRVSDQLEMRSYLDVPRNKSLAIHNMQGRV--
DHTVASD-IRLSDCQTFKPSGASQQPQSNFDVQSSRNNEIGNP-VSSLRSMQSQAFRISQ
NTGPPPIDRQKRLPYPPVQSIPTGNAIPP-RDSENTCHQSFMQSLLAPHLGDQVIGNQRP
LSEHQRNTQCGPSSAIEYNCPPTHESVHIRRESESQNRESCDMSLGAINTRNSTLNIPFS
SSSSSGDIQGRNTSPNVSMQKSNPMRITDSHGTKGHMNPPATTNMHGVARPALPHPSVSH
GNADQGP-PVRQANSSVPQRSRHPLQDS-SGSKIRQPERNRSGNQRHSNVFDPSLPHLPL
STSGSMILGRQQPAAEKRGSIVRFMPDSPQVPNDNSGPDQHTLSQNFGFPFIPEGGMNPP
INANTSFIPQVTQPSATRAPALIPVDPQNTLPSFYPPYSPAHPTLSNDISIPYFSNQMFS
NPSTEKVNSGSLNNRFGSILSPPRPVGFAQPSFPLLPDMPPMHMTN-SHLSNFNMTSLFP
EIATAL-PDGSAMSPLLTIANSSASDSSKQSSNRPAHNISHILGHDCSSAV

----------------------MPEMTEHETPTRKQHRKKNRETHNAVERHRKKKINAGI
NRIGELIPCSPALKQSKNMILDQAFKYITELKRQNDELLLNGGNNEQGNDWRFLALLLFV
R------FLGVS------V-----------------------------------------
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----------------------MPEMTENETPTKKQHRKKNRETHNAVERHRKKKINAGI
NRIGELIPCSPALKQSKNMILDQAFKYITELKRQNDELLLNGGNNEQGFY----------
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----------------------MPEMTEHETPTKKQHRKKNRETHNAVERHRKKKINAGI
NRIGELIPCSPALKQSKNMILDQAFKYITELKRQNDELLLNGGSSEQAEEIKKLRKQLEE
IQKENGRYIELLKANDICLYDDPTIHWKGNLKTSKVSVV---------------------
IPSDQVQKNIIVYSNGSQPGGNSQGTAVQGITFNVGHGLQKQTANVVPVQRTCKLVTPVS
ISGVYPSENKPWHQTTVSALAANQSVPLCLPAAISAQNILELSTSESQSSVLGATGGSV-
-VTVSVGPDPHPHRSLNTCLNDQNA---SENNNAQESPKSSKKTVTCVSGISSSNSAAAP
EVHHENK---SS-PAMQGSSADSQNTL-VS----VTTTVCSQPPRSTGGSS----PVSGS
KTVDSPSTATVVVPAHT-AVAKSILPVSSLSANPLEGGWTLSCSLPSSSVSASELKNISS
LTRISSAGNTQTTWTTLHLAGNTIQPVSQPPSSAATPALNECGTSP---TPNNHKHVATG
I--TLNNSPSTDGQPVEQVVVTLPSCPPLPMQPLIAQPQVKSQPPKSILPLNSAMQVIQM
AQPVGSGVTAAPANQNVIILQPPSTTPCPTMMRAEVSNQTVGQQIVIIQAA-NQNPLPLL
SAPHPGPVRLPVNGASAIIGSHNSVQSVPAPQTFGGKHLVHILPRPSSLS-TSNSTQTFS
VTMSNQQQPQTISLNGQLFALQPVMSSSGTTNQSPMQIIQPTTSEDPNTNVALNTFGALA
SLNQSISQMAGQSCVQLSISQSANPQTSANSQTSPANCVSLTTTVAATITADNSATPSTT
YSLATTSSTNTVTCLPSTMKSKRLSKKPGAKKHLTA-NKPACPLNSVRDVGKIDGPRINS
SAEPSCS-DGLLDSLPIGLS-SVAVSQAK--------N------VSISASHTLDVLNSES
-------------VIPDSDPKSKSTEDCSSPSQESETNEQLVLAPAKPKDSTPILQ-ETS
QGTPPCSVALSSDMKSCTSANVLTPSPIESQSLVSQVSGLSSTTSTSSTDCISEVEIVAE
PCPVQQDS-LDTMQTAGPLKGQGLTMLLSDLAKEKDLQ--KSSISVQMEHPDFSPESSK-
IGDSNVDLPP-KQELLLM-SDERDPPQPHSCLPDQE-VLHGSLLTSRQADSPLSTSSGSS
RSFSVASMLPETAREDVTSSTT-SNTCDGCTFAEQTDIVALAARAILDQESIEKGRLGTQ
--ADVKEVTPKPSET-SLE--GDQPFKPQIHKETCTGQADPTPNEFNSQDSV---EVTVD
--RPLEKPSCSLG-IKGSNAPIQVSASQPPSLTHQ-------NSISSHPLVSCTGLSQSS
DQTSNPVTVNMTVSSSSYGSQPPV-PPLMTEYPQEQLNSMASA-IPNPQVQEPL-SKPSH
ESRKDSAKRTVQDDLLLSSAKRQKHCQPAPLRLESMPLMSRTPDNIPDQTQMMASQITPN
SSNSVVP--VSNPAHGDSLARLFPPSNNFVAPALRQTDVQCNSQPSVAEQQQQQQTQAGQ
HLQALQQH--VPPQGVSHLHTNHLYIKQQQ------------------QQQAGQLRERHH
LYQL-QHHVPHADSAVHSQPHIVHQQRTLQQEVQMQKKRNLVQGTPTSQLSLQPKHHGTD
QSRPKSSQPHPHHQQMQQQLQQHFASSQPEKSCENPSTNRGHH-SHPQNHLNQDVLHQQ-
QDVGSRQQG----SDHVSGHNPMQRLLPSRGLEQ-QMVSQPSIVTRSSDMTCAPHRPERN
RVSSYSAEALIGKSSSTSDQRMGISIQGSRVSDQLEMRSYLDVPRNKSLALHNMQGRM--
DHTVTSD-IRLSDCQTFKPGGASQQPQSNFEVQSSRNNEIGNP-VPSLRSMQSQAFRISQ
NTGPPPIDRQKRLSYPPVQSIPTGNAVPP-RDSENTCHQSFMQSLLAPHLGDQVIGSQRS
LSEHPRNTQCGPSSTIEYNCPPARESVHIRRESESQNRESCDMSLGAINPRSSTLNIPFS
SSSSSGDIQGRNTSPNVSVQKSNPMRITDSHGAKGHMNPPVTSNMHGVARPTLPHPSVSH
GNADQGP-PVRQANSSVAQRSRHPLQDS-SGSKIRQPERNRSGNQRHSNVFDPSLPHLPL
PTSGSMILGRQQPAAEKRGSIVRFMPDSPQVPNDNSGPDQHSLSQNFGFPFIPEGGMNPP
INANTSFIPQVTQPSATRAPALIPVDPQNTLPSFYPPYSPAHPTLSNDISIPYFSNQMFS
NPSTEKVNSGSLNNRFGSILSPPRPVGFAQPSFPLLPEMPPMHMAN-SHLSNFNMTSLFP
EIAAAL-PDGSAMSPLLTIANSSASDSSKQPSNRPAHNISHILGHDCSSAV

----------------------MPEMTENETPMKKQHRKKNRETHNAVERHRKKKINAGI
NRIGELIPCSPALKQSKNMILDQAFKYITELKRQNDELLLNGGNNEQAEEIKKLRKQLEE
IQKENGRYIELLKANDICLYDDPTIHWKGNLKNSKVSVV---------------------
IPSDQVQKNIIVYSNGSQPGGNSQGTAVQGITFNVGHNLQKQTANVVPVQRTCNLVTPVS
ISGVYPSENKPWHQTTVSALASNQPVPLCLPATISAQNILELSTSESESSVLGVTNGSL-
-IAVPVGPEPHQHRSLNTRLNDRHS---SDNKNGQESPKLLKTTTSCATSIPPSSSATAS
KVCQGNK---SC-LSIQDLRGDLQNTLVVS----VTTTVCSQPPRSTGDSS----PVSIS
KSADSTSTTTAVAPSAP-GVGRTTTSVSALSTNSLDSGWT--CSLPSSSVSTSDLKNINS
LTRISSAGNTQTTWTTLQLAGNTIQPLSQTSSSTVTPVLNESG--TSPTTSSHSRHIAPA
V--SLNNSFPADGQPVEQVVVTLPSCPSLPMQPLIAQPQVKSQPPKSILPLNSAMQVIQM
AQPVGSAISAAPANQNVIILQPPSSAPCPAVVRAEVPSQTVGQQIVIIQAA-NQNPLPLL
SAPPPGSVRLPINGANAIIGSNNAMQNVSAPQTFGGKHLVHILPRPSSLS-TSNSTQTFS
VTMSNQQQPQTISLNGQLFALQPVMTSSGTTNQTPMQIIQPTTSEDPNTNVALNTFGALA
SLNQSISQMAGQSCVQLSISQPANSQTAAKSQTTPANCVPLATAVAPPVTTDNSATLPST
YNLVTAPPANTVTCLPPTVKSKRLNKKPGAKKPLAA-SKPACPLNAGRDAGKLDCPRAEG
SAEPSCN-DGLLENLPSVLP-SVAVSQSN--------T------VSVPVSQSSDVLNSQS
-------------VIPESVSKYKSAEESPSPSQESVTSEHFTVAPAKPKDSTPTLQQETS
QDKTAASSALSDAATSCTSASVFIPSPNDAHVLASQVSDLSSTASTTTTDCVSEVEIIAE
PCRVEPDS-SNTAQNTGVLKGQGLTTLLSDLAKEKDPQ--KSPLSMQMDNPDFSSENSK-
TADSGVALHP-KQELLLMNNDERDPPQHHSCLPDQE-AISGSLLSSRQADSPMSTSSGSS
RSFSVASMLPETTREDVTSHAT-THACDSCTFAEQTDIVALAARAIFDQENLEKGRVSVQ
--ADRREVASKPPEASPLE--GDQPFKSQLPKENGPGQAEGAPNGLHAQDSV---EAAV-
-----EKSSCSLG-IKTSNAPLQVSTSQPPSITSLSVNNLIHQSSISRPLVSCAGLAQTS
EPTTVPATVGLTVPSSSYGSQPPG-PSLMTEYSQEQQLSTMTSAIPNSQIQEPL-LKSSH
EGRKDSAKRAVQEDLLLSSAKRQKHCQPAPLRLENMSLMSRTPDSISDQTQMMVSQMPPN
SSNSVVP--ASTPAHGDGLTRLFPPSSNFVAPVLRQAEVQCGSQPPV-AEQ--QQTQASQ
HLQALQQH--VPAQAVSHLHSNHLYVKQQQQQQ-------------QQQQQAGQLRERHH
LYQL-QHHVPHAENAVHSQPHSVHQQRTLQQEVQMQKKRNLIQP-QASQLSLQPKHHGTD
QSRPKSGQPHPHHQQLQQQMQQHFGSSQPEKNCENPSASRPHH-NHPQNHLSQDILHQQ-
QDVGSRQQGSAVSSEHVSGHNPMQRLLTSRALEQ-QMVSQPSIVSRPSDMPCTPHRPERN
RVSSYSAEALIGKTSSNSEQRMGISIQGSRVSDQLEMRNYLDVPRNKSLAIHNMQARV--
DHTVASE-IRLSDCQTFKPSGASQPPQSNFEVQSSRNNEIGNPSVSSLRSMQSQAFRISQ
NTGPPPIDRQKRLPYPPVQSIPSGNAIPP-RDGENTCHQSFMQSLLAPHLGDQVIGNQRS
LSEHQRNAQCGPSSAIEYNCPPAHESVHIRRESESQNRESCDMSLGAINTRNSALNIPFS
SSSSSGDIQGRNTSPSVSVQKSNPMRITDSHGTKGHMNPPVTTNMHGVARPALPHPSVSH
GNADQGA-PVRQANSSVAQRSRHPLQDS-SGSKIRQPERNRSGNQRHSNVFDPSLPHLPL
STSGSMILGRQQPAAEKRGSIVRFMPDSPQVPNDNSGPDQHTLSQNFGFPFIPEGGMNPP
INANTSFIPQVSQPSATRTPALIPVDPQNTLPSFYPPYSPAHPTLSNDISIPYFSNQMFS
NPSTEKVNGGSLNNRFGSILSPPRPVGFAQPSFPLLPDMPPMHMTN-SHLSNFNMTSLFP
EIATAL-PDGSAMSPLLTIANSSASDSSKQSSNRPAHNISHILGHDCSSAV

----------------------MPEMTEHETPTKKQHRKKNRETHNAVERHRKKKINAGI
NRIGELIPCSPALKQSKNMILDQAFKYITELKRQNDELLLNGGNNEQAEEIKKLRKQLEE
IQKENGRYIELLKANDICLYDDPTIHWKGNLKNSKVSVV---------------------
IPSDQVQKNIIVYSNGSQPGGNSQGTAVQGITFNVGHNLQKQTANVVPVQRTCNLVTPVS
ISGIYPSENKPWHQTAVSALAANQPVPLCLPAAISAQNILELPAPESEAGAPGATGGSL-
-IAVSVGPEPRQHPSSHICPNDQNS---SENNTGLDSTRLLKKTAPCVTSVSPSSSANPT
KVHHGTK---SC-LSLQNCRGDLQSAFAVS----VTTTVWCQPPRCAGDSA----PLSIS
KCTDSTNATTVVAAAAP-GVGKT------LSASPLDSGWTLSCSLPSSSASASDLKNINS
LTRISSAGNTQTTWTTLQLAGNTIQPLSQTPSSTVTPVLSESG--TGPPTSNHSSHVATG
I--SLNNSLPADGQPSEQVVVTLPSCPPVPMQPLISQPQVKSQPQKNLLPLNSAMQVIQM
AQPVGSAVNGASANQNVIILQPPSTTPCPTVMRAEVPSQTVGQQIVIIQAA-NQNPLPLL
SAPPPGSVRLPVNGANAIIGSSNAVQNVSTPQTFGGKHLVHILPRPSSLS-VSNSTQTFS
VTMSNQQQPQTISLNGQLFALQPVMSSSGTTSQTPMQIIQPTTSEDPNTNVALNTFGALA
SLNQSISQMAGQSCVHLSISQPANPQTAANSQTTPANCVSLTTSIAPPTTTDNSATLPST
YNLVTTSSINTAACLPPAMKSKRLNKKPGAKKHLAA-SKPACPLNLVREVGKLDCPRTEG
SAEPPCS-DGLLDTLPVVLP-SVAVSEAN--------NV------SASASHSLDVLNSES
-------------AMPESVSKSKSVEESSSPRQESVTSEHFAAALEKSKNSMPILEQETS
QDRPPTSLGLSDATKSCTSASVLIPSPRDPQILVSQVSGLSSTTSTTSTDCVSEVEIITE
PCRVEQGS-SDTMQAAGLLKGQGLTTLLSDLAKEKDPQ--KSSLSVQISHPDFSSENGK-
VADASVDLHP-KQELLLLSSEDRDPPQQHSCLPDQE-VMNGSLL-TRQADSPMSTSSGSS
RSFSVASMLPETTREDVTSSTT-TNTCDSCTFVEQTDIVALAARAIFDQENIEKGRVGIQ
--ADIREVASKSSETSSLE--GDQPFKSHIPKENGTGQRETTANEFNSQDSI---EVTVE
--RPLEKPSCSLG-SKTSNASLQAASSQPPSLTSLSVNNLIHQSSITHPLVSCAGLSQTS
DQTTVPTTVNLTVSSSAYSSQPPG-PSLMTEYSQEQLNTMAST-IPNSQIQEPL-LKPNH
ENRKDSAKRAVQDDLLLSSTKRQKHCQPAPLRLENMSLMSRTADSIPDQAQMMVSQLPPS
SSNTVVP--VSNPAHGDGLTRLFPPANNFVTPALRQTEVPCSSQPSV-AEQ--QQTQASQ
HLQALQQH--VPPQGVSHLHSNHLYIKQQQQ------------------QQAGQLRERHH
LYQL-QHHVPHVENVVHSQPHSVHQQRTLQQEVQMQKKRNLVQGTQGSQLSLQPKHHATD
QSRPKSGQPHPHHQQMQQQMQQHFGSSQPEKSCENPSASRNHH-SHPQNHLSQDIMHQP-
QDVGSRPQGSGVSSEHVSGHNPMQRLLTSRGLEQ-QMVSQPSIVTRSSDMTCTPHRPERN
RVSSYSAEALIGKTSSNSEQRMGISIQGSRVSDQLEMRSYLDVPRNKSLAIHNMQGRV--
DHTVASD-IRLSECQTFKPSGASQQPQSNFEVQSSRNNEIGNS-VSSLRSMQSQAFRISQ
NTGPPPIERQKRLPYPPVQSIPTGNAIPP-RDSENTCHQSFMQSLLAPHLGDQVIGNQRS
VSEHQRNTQCGPSSAVEYNCPPTHESIHIRRDSESQNRESCDMSLGAVNTRNSTLNIPFS
SSSSSGDIQGRNTSPNVSVQKSNPMRITDSHGTKGHMNPPATTNMHGVARPALPHPSVSH
GNADQGP-PVRQANTSVPQRSRHPLQDS-GSSKIRPPERTRSGNQRHSNVFDPSLPHLPL
STSGSMILGRQQPATEKRGSIVRFMPDSPQVPNDNSGPDQHSLSQNFGFPFIPEGGMNPP
INANTSFIPQVTQPSATRTPALIPVDPQNTLPSFYPPYSPAHPTLSNDISIPYFSNQMFS
NPTTEKVNSGSLNNRFGSILSPPRPVGFAQPSFPLLPDMPPMHMTN-SHLSNFNMTSLFP
EIATAL-PDGSAMSPLLTIANSSASDSSKQSSNRPAHNISHILGHDCSSAV

----------------------MPEMTENETPTKKQHRKKNRETHNAVERHRKKKINAGI
NRIGELIPCSPALKQSKNMILDQAFKYITEMKRQNDELLLNGGNNEQAEEIKKLRKQLDE
LQKENGRYIELLKANDICLYDDPTIHWKGNLKNAKVSVV---------------------
IPSDQVQKNIIVYSNGTQPNGNNQGASVQGITFNVGHNLQKQTANVVPVQRTCNLVTPVT
IAGIYPTENKPWSQPTVSPLASVQTP--------PAGNVLELSTPENERGVPTTAPASSQ
STLRPAAEQELQCSSSKAPQIEQNP---PKSKNDEEGTKSTKKTLLQGTSLPSSASVEAS
QVQQVNT---TC-SNTHNSRSDFQETCAIS----ATDTACVPPVRLSTAES--CSSPGVL
KSMDVVSSAGMPATSAA-EGVKAVTAISTLAASPLENCWSFSG---SSGVGTSDLKNMSS
LTRMPSAGNTQTTWTTLQLAGNTVQPLSQTQSGIMTAVLNEPVSGAGTVSSTHSRPVTTS
I--SLHASLPGDSQSAEQIVVTLPSCPPVPIQPLISQSQVKAQAAGNILPLNSAMQVIQM
AQPVASAVTGAPANQNVIILQPPNPAPCPPIVRAEVPSQNVSQQIVIIQAA-NQNPLPLL
SAQPSASVRVPVNGPTVVANSSGSMQNASLPQTFGGKHLVHILPRPSSLP-SSSSTQTFS
VTMSNQQHPQTISLNGQLFALQPVMSSSGASNQAPMQIIQPTTSEDPNTNVALNTFGALA
NLNQSISQMAGQSCLHLSLSHPTNPATV-NNQIATVNCVSLPTSVASSVPAEVSALT-SA
SNSINASPQKVAAGLPSSAKSKRTNKKPSTKKHQAVNNKVTCSAVPCKNAGKVDCGSVEM
VAKPSNG-KGLPENTPAVSQ-AVTTLQVG--------GTAALSGVSISDSSSKETVSSEQ
A------------VKTPSAPEPSSAEGPTSSPLEPVVSEQLLLAPPPAKDAAPQQQAQGS
QSHPPTASELSESPKPCEPPNTLTSSRKEAQVTHLQVANGTSAVQSNTAGHTSKAGIISE
SCNVAQDS-SVAMQDADLLEGQGLTKMLSDLTKERTAVEKTSSFAVQGEHSNFPMENSK-
SAESNVDLPE-KQELLLMNTESDTLSQPPSCISDQE-VVSASLITSRQADSPMSTSSGSS
RGFSVASMLPDTTREDVTSSTS-TSTCNSCTFSEQTDIVALAARAIFDQESLEKGGGGIQ
V--NTRDVISKSEVAPLER--EQQPFKPQSVKENNAGVQETAPNKFSTHETV---PTNVD
--RQVEKPSCSVGGVETSNTPLQISTSQTPNITSLSVNNLIHQSRIVHPLVSCSGLSQSS
EPGSVPAAVSLSLPSRTYINPSPG-PALMSEYAQEQLNAIRASTMQAPQLQESHLKQQNH
EGRKDSAKRAVQDDLLLSTAKRQKQCQTAPIRLEGMALINRTPEGIADQTQMLVSQIPPN
SSNSVAP--VSNQGHADGLNRLFPPNSNFVMPALRQTEVQCGSQPPLS--E--QPGQTGQ
HLQPI-QH--VPAQGISHLHSNHPYLKQ---------------------QQAGQLRERHH
LYQL-QHRVTHGENSVHSQPHSVHQQRTIQQEVQMQKKRNLIQGTQATQLSLQQKHHGSD
QTRQKGGQPHPHHQQMQQQMQQHFGASQPEKNCENPATSRNHH-NHPQSHINQDIMHQQQ
QDVGSRQQG--STSEHVSGHNQMQRLMTSRGLEQ-QMVSQASIVTRPSDMTCTPHRQERN
RVSSYSAEALIGKTPSNSEQRIGISLQGPRVSDQLEMRSYLDVSRSKGLAIHNMQGRLSV
DHTVGSDVQRLSDCQTFKPSGPNQQPTGSFDVQASRNSEIGNS-VSSLRGMQSQAFRIGQ
NAA-PSIERQKRLPYQPVQSIPTGNTLPS-RENENTCHQSFMQSLLAPHLGDQVSGSQRS
IPEHQRNTQCSASSTIEYNCPPARESVHIRRDGDGQSRESCDMSIGAINTRNSSLTIPFS
SSSSSGDIQGRNTSPNISVQKSNPMRMTDSHGTKNHMNTPVSSNMHGGVRPTHPHPAVSH
GNGEQGQPSVRQPNSSVTQRSRHPLQDN-GGSKIRQPERNRSGNQRHGNVFDPSLPHLPL
STSGSMILGRQQSTIEKRGSIVRFMSDGPQVSNDNTTPDQHTLSQNFGFPFIPEGGMNPP
INANTSFIPPVTQPSATRTPALIPVDPQNTLPSFYPPYSPAHPTLSNDISIPYFPNQMFP
NPPTEKPSSGGLNNRFGSILSPPRPVGFAQPSFPLLPDMPPMHMTNTSHLSNFNLTSLFP
EIATALPPDGSAMSPLLSIANTSASDSSKQPSNRPAHNISHILGHDCSSAV

----------------------MPEMTENETPTKKQHRKKNRETHNAVERHRKKKINAGI
NRXXXXXXXXXXXXXSKNMILDQAFKYITELKRQNDELLLNGGNNEQAEEIKKLRKQLEE
IQKENGRYIELLKANDICLYDDPTIHWKGHLKNSKVSVV---------------------
IPSDQVQKNIIVYSNGSQPGGNSQGTAVQGITFNVGHNLQKQTANVVPVQRTCNLVTPVS
ISGVCPSENKPRHQTTVSALAANQPVPLCLSATVSAQNVLELSTSESESSVLGAPSGSL-
-MAAPVGPEPHQRRSLHTSLNDQNS---SENKNGQESPQSLKKTVSCTSHLPSSSSAAAT
TVQHSSK---PC-LSTQSFRSEFQNTLIVS----VTTTVCCQPPRPAGGSF----PVGIS
KGTDATNSKTVGVPSVP-GVGKTATPVSAVSSNPLDSGWALSCSLPSSSVSASDLKNINS
LTRISSAGNTQTTWTTLQLAGNTIQPLSQTPSIAVTPVINESG--TTPTTTNRSRHVTIG
I--NLSNSFPADGQAVEQVVVTLPSCSPLPVQPLIAQPQVKSQPPKNILPLNSAMHVIQM
AQPVGSAVNAAPANQNVIILQPPSTTPCPTVMRAEVPSQTIGQQIVIIQTA-SXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXSAPQTFGGKHLVHILPRPSSLS-TSNSTQTFS
VAMSNQQQPQTISLNGQLFALQPVMSSSGTTNQTPMQIIQPTTSEDPNTNVALNTFGALA
SLNQSISQMAGQSCVQVSASPPANPQTAVNSQTTSANCASLTTTVAPPLTTDNSATLPST
YNLVTTSSVNTVASLPPNVKSKRLNKKPVAKKHSAA-NRSACPLNPVREVGKLDCPSTEG
SAEPSCN-DVLLDSLPVDLP-CVAGSQAS--------S------VSVSSSHSL---SS--
---------------EESVATCKPAEEPNSPSRKCVTHERFAATPAKSKDSTPALQQETS
QEKPPTTLALSDAAKSCTSASVLISSPNDPHVLVSQVSGLSSTANTTSTDCVSEVEIVAD
PCRIEQEP-SDSVQTTGLLKGQGLTALLSDLAKEKDAQ--KTSLSVQVDHPDFS-ENSKV
VVDSGMDLHP-KQELLLLSSDGRDPPQHHSCLPDQE-VINGSLLTSRQADSPMSTSSGSS
RSFSVASMLPEAAREDVTSSAT-TSTCDSCTFVEQTDIVALAARAIFDQENLEKGRVGIP
--ADVREATSKPSEQSSLE--GDQPFKSQTPKENGTGQAEAVPNDFHSQDSL---EVAVD
--RPLEKPSCSVG-IKTSDASLQVPSSQPPSITTLSVNNLIHQSGISHPLVSCAGLSQSS
EQTSVSAAVHPTASSSSCGGQPPG-PSLMTEYAQEQLNTMTST-MPNSQVQEPL-LKSSH
ESRKDSAKRTVQDDLLLSSAKRQKHCQPAPLRLESMSLMSRTPESIADQTQIMVSQIPPN
SSNSVAS--GSSATHGDGLTRLFPPGNNFVAPALRQTEVQCSSQPSVAEQ---QPTQTGQ
HLQALQQH--VPAQGVSHLHSNHLYLKQQQQQQQ-----------QQQQQQVGQLRERHH
MYQL-QHHVPHAESSVHSQAHSVHQQRTLQQEVQMQKKRNLVQGTQASQLSLQPKHHGTD
QSRPKSGQPHPHHQQMQQQMQQQFGNSQPEKSCENPSTSRNHP-NHPQNHLTQDIMHQP-
QDVGSRQQGSGVSSEHVSRHNPMQRLLTSRGLEQ-QMVSQPSIVTRPSDMSCTPHRPERN
RVSSYSAEALIGKTSSNSEQRMGLSIQGSRVSDQLEMRNYLDIPRNKNLAIHNMHSHM--
DHTVTPD-IRLSDCQTFKPAGASQQPQSNFEVQSSRNNEIGNP-VSSLRSMQSQTFRISQ
NTGPPPIDRQ-RLPYPPVQSIPTRNAIT---DSDSACHQSFMQSLLAPHFNDQVIGSQRS
LSEHQRNTQCGPSSAVEYNCPPAHESVHIRRESESQNRESCDMPLSAINTRNSTLNIPFS
SSSSSGDIQGRNTSPNVSVQKSHPVRITDSHGTKGHLNPPVTTNMHGVARPALSHPSVSH
GSADQGP-PVRQSSSSVPQRSRHPLQDS-SGSKIRQPERSRSGNQRHSNVFDPSLPHLPL
STSGSMILGRQQPATEKRGSIVRFMPDSPQVPNDNSAPDQHTLSQNFGFSFIPEGGMNPP
INANTSFIPQVTQPSATRTPALIPVDPQNTLPSFYPPYSPAHPPLSNDISIPYFSNQMFS
NPSTEKVNSGSLNNRFGSILSPPRPVGFAQPSFPLLPDMPPMHMAN-SHLSNFNMTSLFP
EIATAL-PDGSAMSPLLTIANSSASDSSKQSSNRPAHNISHILGHDCSSAV

-------------MRKVLLSVTMPEMTENETPTKKQHRKKNRETHNAVERHRKKKINAGI
NRIGELVPCSPALKQSKNMILDQAFKYITELKRQNDELLLNGGNHEQAEEIKKLRKQLEE
TQRENGRYIELLKANDICLYDDPTIHWKGNLKNAKVSVV---------------------
IPSDQIQKNIIVYSNGSQPGGNNQATAVQGITFNVGHNLQKQTANVVPVQRSCNLVTPVS
LSGVFPPENKPWHQTPVSSLTANQSVPLCLPAAIPAQNILEISTSENESSVLSSNSSQ--
-ITVPSGSESNQLSSSSMPLSGHNA---SESKNGQESPKLPKRPMSCATSISPSTSVLSF
QVQPGNK---SC-LSLQDFRSDCQDNFVVP----VADTACSQPLRPSIPRN--SSPVNIS
KNTDLTSSAGVEAPSVA-LAVKATTAISTVSASHLDSGWSLSCSLPSSSVNASDLKNINS
LTRIPSSGNTQTTWTTLQLAGNTVQPLSQTPSTIVTPILNEPGS--STSAPNHNRHMATC
---VLNGSYPSDGQQVEQVVVTLPSCPSLPMQPLIAQPPIKTQPPPNILPYNSTMQVIQM
AQPVGSAVNAGSANQNVIILQPPSTTPCPGVMRAEVPNQTVGQQIVIIQAA-NQNPLPLL
SAPPPGSVRVSVNGANPVVVSNNSVQNVSAPQTFGGKHLVHILPRPSSSSSSSNSTQTFS
VTMSNQQQPQTISLNGQLFALQPVMSSSGATNQTPMQIIQPTTSEDPNTNVALNTFGALA
SLNQSISQMAGQSCVQLAIGQPANPPPATTSRVTPVNCVSLPTTAASPLTTDNTAVLSNT
ANHMNISPVKALASLPSNVKSKRVIKKPGPKKHVA--NKSACPVNPNRDSGKLDCANTEG
STPQSCA-DGLLESLPVALT-PATETQAN--------S------VNASDSHSFEGVSSEP
-----------------LVSESHSLEVSHSPSQEPITSEHFVLTSPDPRDSVSTLQSGRS
QSKPATSPEVSDSSRSCISSGLLIPSPSDPHILVSQIPGSSSTQSTTSTSGASGVEIISE
PCRQDS---SAAVQATGLLKGHGLTALLSDLTKEKEGQ--KTPLSAQVDHPNFPSENSK-
IVGSSIELPQ-KQELLLMNGEGGNLSQHHSCIPDQE-AINSSLLASRQTDSPMSTSSGSS
RGFSVASMLPDTTREDVTNSTS-ASTCDNCTFAEQTDIVALAARAIFDQENLEKGRVGVQ
--TDIQETTSKPSEASSLE--GEQPFKTQAAKENATGQVEATANEFSSQDSV---QANVD
--RSLEKPSCSVS-TETSHASIQVSTSQSPSISSLSVNNLIHQSSINHPLVSCS------
EQPAIPATVNLSVSSSSYVTQPPE-PSLMAEYSQDQLNTMTN--IPNSQIQESH-LKSSH
ESRKDPAKRPVQDDLLLSTAKRQKHCQPAPLRLEGMSLMSRTPDNIADQTQMMVGQIPPN
SSNSVVP--VSNPGHVDDLSRLFPPN-NFVTSALRQPEVQCNSQPSMTEQQ--QSQAGSQ
HLQSLQQQHVPPAQGISHLHNNHPYLKQQ--------------------QQAGQLRERHH
LYQL-QHHVPHADSSIHSQSHGVHQQRTIQQEVQMQKKRNLVQGTQAPQLSIQQKHHGSD
QSRPKGGQPHPHHQQMQQQMQQHFGNSQSEKSCENPSTSRTHH-NHPQNHLNQDIMHQQ-
QDVGSRQQSSGVSSEHVTAHNPMQRLMPPRGLEQ-QMVSQPSIVTRSSDMTCTPHRPERN
RVSSYSAEALIGKTSSNSEQRMGISVQGPRVSDQLEMRSYLDVPRNKGLAIHNMQSRV--
DHTVASE-VRLSDCQTFKPSGASQQPQSNFEVQSSRNNEIGNP-VSSLRGMQSQAFRISQ
NNG-PPIDRQKRLPYPPVQSLPAGNTIPP-RDNENACHQSFMQSLLAPHLGDQVIGSQRS
ITEHQRNTQCGPSSTIEYNCPPAHESIHIRRESETQNRESCDMSLGAINTRNSSLTIPFS
SSSSSGDIQGRNTSPNVSVQKSNPMRMTESHGTKGHMNPPVTSNIHGVARPSLPHPAVSH
GSADQGPPSVRQPNSSVTQRSRHPLQDSSGGSKIRQAERNRSGNQRHNNVFDPSLPHLPL
STSGSMIIGRQQSSTEKRGSIVRFMPDSPQVSNESAAPDQHTLSQNFGFPFIPEGGMNPP
INANTSFIPQVTQPSATRTPALIPVDPQNTLPSFYPPYSPAHPTLSNDISIPYFSNQMFS
NPSTEKVNSGGLNNRFGTILSPPRPVGFAQPSFPLLPDMPPMHMTN-SHLSNFNMTSLFP
EIATAL-PDGSAMSPLLTIANSSASDSSKQTSNRPAHNISHILGHDCSSAV

----------------------MPEMTENETPTKKQHRKKNRETHNAVERHRKKKINAGI
NRIGELIPCSPALKQSKNMILDQAFKYITELKRQNDELLLNGGNNEQAEEIKKLRKQLEE
IQKENGRYIELLKANDICLYDDPTIHWKGNLKNSKVSVV---------------------
IPSD-------------QPGGNSQGTAVQGITFNVSHNLQKQTANVVPVQRTCNLVTPVS
ISGVYPSENKPWHQTTVPALATNQPVPLCLPAAISAQSILELPTSESESNVLGATSGSL-
-IAVSIESEPHQHHSLHTCLNDQNS---SENKNGQENPKVLKKMTPCVTNIPHSSSATAT
KVHHGNK---SC-MSIQDFRGDFQNTFVVS----VTTTVCSQPPRTAGDSS----PMSIS
KSADLTSTATVVASSAP-GVGKATIPISTLSGNPLDNGWTLSCSLPSSSVSTSDLKNINS
LTRISSAGNTQTTWTTLQLAGNTIQPLSQTPSSAVTPVLNESG--TSPTTSNHSRHVATD
I--NLNNSFPADGQPVEQVVVTLPSCPSLPMQPLIAQPQVKSQPPKNILPLNSAMQVIQM
AQPVGSAVNAAPTNQNVIILQPPSTTPCPTVMRAEVPNQTVGQQIVIIQAA-NQNPLPLL
PAPPPGSVRLPINGANTVIGSNNSVQNVPTPQTFGGKHLVHILPRPSSLS-ASNSTQTFS
VTMSN-QQPQTISLNGQLFALQPVMSSSGTTNQTPMQIIQPTTSEDPNTNVALNTFGALA
SLNQSISQMAGQSCVQLSISQPANSQTAANSQTTTANCVSLTTTAAPPVTTDSSATLAST
YNLVSTSSMNTVACLP-NMKPKRLNKKPGGRKHLAA-NKSACPLNSVRDVSKLDCPNTEG
SAEPPCN-DGLLESFPAVLP-SVSVSQAN---------SVSVSAS-----HSLGVLSSES
-------------LIPESVSKSKSAEKSSPPSQESVTSEHFAMVAAKSKDSTPNLQQETS
QDKPPSSLALSDAAKPCASANVLIPSPSDPHILVSQVPGLSSTTSTTSTDCVSEVEIIAE
PCRVEQDS-SDTMQTTGLLKGQGLTTLLSDLK---------SSLSHQMDHPDFSSENPK-
IVDSSVNLHP-KQELLLMNNDDRDPPQHHSCLPDQE-VINGSLITGRQADSPMSTSSGSS
RSFSVASMLPETTREDVTSNAT-TNTCDSCTFVEQTDIVALAARAIFDQENLEKGRVGLQ
--ADIREVASKPSEASLLE--GDPPFKSQIPKESGTGQAEATPNEFNSQGSI---EATME
--RPLEKPSCSLG-IKTSNASLQDSTSQPPSITSLSVNNLIHQSSISHPLASCAGLSPTS
EQTTVPATVNLTVSSSSYGSQPPG-PSLMTEYSQEQLNTMTST-IPNSQIQEPL-LKPSH
ESRKDSAKRAVQDDLLLSSAKRQKHCQPAPLRLESMSLMSRTPDTISDQTQMMVSQIPPN
SSNSVVP--VSNPAHGDGLTRLFPPSNNFVTPALRQTEVQCGSQPSV-AEQ--QQTQASQ
HLQALQQH--VPAQGVSHLHSNHLYIKQQQQQQ------------QQQQQQAGQLRERHH
LYQM-QHHVPHAESSVHSQPHNVHQQRTLQQEVQMQKKRNLVQGTQTSQLSLQPKHHGTD
QSQSKSGQPHPHHQQMQQQMQQHFGSSQTEKSCENPSTSRNHH-NHPQNHLSQDIMHQQ-
QDVGSRQQGSGVSSEHVSGHNPMQRLLTSRGLEQ-QMVSQPSIVTRSSDMTCTPHRPERN
RVSSYSAEALIGKTSSNSEQRMGISIQGSRVSDQLEMRSYLDVPRNKSLAIHNMQGRV--
DHTVASD-IRLSDCQTFKPSGASQQPQSNFEVQSSRNNEIGNP-VSSLRSMQSQAFRISQ
NTGPPPIDRQKRLPYPPVQSIPTGNGIPS-RDSENTCHQSFMQSLLAPHLSDQVIGSQRS
LSEHQRNTQCGPSSAIEYNCPPTHENVHIRRESESQNRESCDMSLGAINTRNSTLNIPFS
SSSSSGDIQGRNTSPNVSVQKSNPMRITESHATKGHMNPPVTTNMHGVARPALPHPSVSH
GNGDQGP-AVRQANSSVPQRSRHPLQDS-SGSKIRQPERNRSGNQRQSTVFDPSLPHLPL
STGGSMILGRQQPATEKRGSIVRFMPDSPQVPNDNSGPDQHTLSQNFGFSFIPEGGMNPP
INANASFIPQVTQPSATRTPALIPVDPQNTLPSFYPPYSPAHPTLSNDISIPYFPNQMFS
NPSTEKVNSGSLNNRFGSILSPPRPVGFAQPSFPLLPDMPPMHMTN-SHLSNFNMTSLFP
EIATAL-PDGSAMSPLLTIANSSASDSSKQSSNRPAHNISHILGHDCSSAV

----------------------MPEMTENETPTKKQHRKKNRETHNAVERHRKKKINAGI
NRIGELIPCSPALKQSKNMILDQAFKYITELKRQNDELLLNGGNNEQAEEIKKLRKQLEE
IQKENGRYIELLKANDICLYDDPTIHWKGNLKNSKVSVV---------------------
IPSDQVQKNIIVYSSGSQPGGNSQGTAVQGITFNVGHNLQKQTANVVPVQRTCNLVTPVS
ISGVYPSENKPWHQTTVSALAANQPVPLCLPATISAQNILEVSXXXXXXXXXXXXXXXX-
-XXXXXXXXXXXXXXXXXXXXDQNF---FLYMNGQECPKLLKKTFPCATSISPSCSATAT
KGHEGSK---SC-LGVQECRSDFQTTSVVS----VTTTVCSQPPRSAGDSC----PASIS
KGADLTSVTAVVAPSAP-GGGETTTPVSTLSANPVDSGWTLSCSLPSSAVSASDLKNINS
LTRISSAGNTQTTWTTLQLAGNTIQPLSQTSSSAVTPVLNESG--TSPTTANHSRCVATG
V--NLNNSFPADGQPVEQVVVTLPSCPSLPMQSLIAQPQVKSQPPKSILPLNSAMQVIQM
AQPVGSAVSAAPANQNVIILQPPSTTPCPAMMRAEVPNQTVGQQIVIIQAT-NQNPLPLL
SAPPPGSVRLPVNGASAIIGSNNSVQNVSTPQSYGG-HLVHILPRPSSLS-ASNSTQTFS
VTMSNQQQPQTISLNGQLFALQPVMSSSGTTSQTPMQIIQPTTSEDPNTNVALNTFGALA
SLNQSISQMAGQSCVQLSVSQPANPQTAANSQTTPANCVALTTAVASPVTTENSATLPST
YNLVTTPSMNTVACLP-NMKPKRLNKKPSVKKHVAT-NKSACTLNPARDVGKLDCPSTEG
STEPSCN-DGLLDSLPGVLP-SVTMSQVN---------SVSVSGS-----HSLDVLNSES
-------------VIPESIPKSKSAEESSSSSQESVTSEHFTMAPAKSKDSLPVLQRETS
QDKPAASLALPAAAKSCTSANVLISSANDPHVLVSQVSDLSSATSTASTDCVSEVEVIAE
PCRAEQGS-SATVHTTGLLKGQGLTALLSGLAKEKDPQ--KSPLSVQVDHPDFSSENSK-
IVHSNVDLHP-KQELLLMSSEDRDPGQHHSCISDQE-VINGSLLTSRQADSPMSTSSGSS
RSFSVASMLPETTREDVTSSAT-TNTCDSCTFVEQTDIVALAARAIFDQENLEKGRAGAQ
--ADIREVPSKPSEASSLE--GDQPFKTQISKENGPGQAEATPNEFNSQESI---EATVG
--RPLEKPSCSIG-MKTSNASLQVSTSQPPSITSLSVNNLIHQSSISHPLVSCAGLAQTS
EPTAAPATVNLTVSSSSYGSQPPG-PSLMTEYSQEQLSTMAGT-IPNPQIQEPL-LKPSH
ESRKNSAKRAVQDDLLLSSAKRQKHCQPAPLRLEGLSLMSRTPDSISDQTQMMVSQIPPN
SSNSVVP--ISNPAHGDSLTRLFPPGNNFVAPALRQTEVQCNSQPSV-AEQ--QQTQASQ
HLQALQQH--VPAQGVPHLHSNHLYLKQQQ-------------------QQAGQLRERHH
LYQL-QHHAPHAESSVHSQPH-VHQQRTLQQEVQMQKKRTLVQGTQASQLPLQPKHHGSD
QSRPKSGQPHPHHQQMQQQMQQHFGSSQPEKSRENPSTSRSHH-N----HLSQDIMHQ--
QEVGSRQQGAGLSSEHVSGHNPMQRLLTSRGIEQ-QMVSQPSIVTRPSDMTCTPHRPERN
RVSSYSAEALIGKTSSNSEQRMGISIQGSRISDQLEMRSYLDVPRNKSLAIHNMQGRV--
DHTVTSD-IRLSDCQTFKPSGASQQPQSNFEVQSSRNNEIGNP-VSSLRSMQSQAFRISQ
NPGPPPIDRQKRLPYPPVQSIPTGNAVPP-RDSENTCHQSFMQSLLAPHLGDQVIGSQRS
LPEHQRNTQCGPSSAIEYNCPPTQKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXX-XXXXXXXXXXXXXXXXXXXX-XXXXIRQPERNRSGNQRHSNV-DASLPHLPL
STSGSMILGRQQPATEKRGSIVRFMPDGPQVPNDNSAPDQHTLSQNFGFPFIPEGGMNPP
INANTSFIPQVTQPSATRTPALIPVDPQNTLPSFYPPYSPAHPTLSNDISIPYFSNQMFS
NPSTEKVNSGSLNNRFGSILSPPRPVGFAQPSFPLLPDMPPMHMTN-SHLSNFNMTSLFP
EIATAL-PDGSAMSPLLTIANSSASDSSKQSSNRPAHNISHILGHDCSSAV

-------------MRKVLLSITMPEMTENETPTKKQHRKKNRETHNAVERHRKKKINAGI
NRIGELVPCSPALKQSKNMILDQAFKYITELKRQNDELLLNGGNHEQAEEIKKLRKQLEE
IQRENGRYIELLKANDICLYDDPTIHWKGNLKNAKVSVV---------------------
IPSDQIQKNIIVYSNGSQPGGNSQGTAVQGITFNVGHNLQKQTANVVPVKRTCNLMTPVS
NAGVYPPENKPWHQTTVSSLAASQSVPLCLPAAIPAQNILELSTSESESSVLNSNSSQ--
-IILPSGSESHQPNSSNIPPSGQNA---SESKNGQESPKLP-KTVSCATSIPPSTSGLSF
QVQHGNK---SC-PGLQHFRSDCQDNFVAL----GADMACSQTLRPSVPRN--SSPLSIN
KNTDLMSRAGVETPSVA-LAVKPATSVSMVSASHLDSGWSLSCSLPSSSVSASDLKNINS
LTRIPSSGNTQTTWTTLQLAGNTVQPLSQTPSTIVTPILNEPGT--GTSATNHSRHMASN
I--SLNGSFPTDGQQIEQVVVTLPSCPSLPMQPLIAQPTVKTQPPPNILPFNSTMQVIQM
AQPVGSAVNAGPANPNVIILQPPTTTPCPGVMR-EVPNQTVGQQIVIIQAA-NQNPLPLL
SAPPPSSVRVSVNGASPVVVSNNSMQNVLTPQTFGGKHLVHILPRPSSSS-SSNSTQTFS
VTMSNQQQPQTISLNGQLFALQPVMSSTGATNQTPMQIIQPTTSEDPNTNVALNTFGALA
SLNQSISQMAGQSCVQLAISQPANPPPATTSRITPVNCVSLPTTAASPITTENTTVLPST
ANQMNTSPVKALTSLPSNVKSKRVNKKPGPKKHVT--NKSACLANPIRDSGKLDCANTEG
SSEQSCA-DGLLESLPVVLT-PTVESQAN--------S------VSVSDSHAFEGVNSEP
-----------------IVSESNSLEVSHSPSQEPVTVEHFVLAS--TKDSVSALQSGRS
QSKPTASAELSDSSKSCISPGILVPSPNDPHILVSQVPASSSTQSITSTNSASEVEIAAE
PCRQDS---AVAMQATGLLKGHGLTALLSDLTKEKDGQ--KTPLSSQVDHPNFSSENSK-
IIGSGIDLPQ-KQELLLMNSDSGNLPQHHSCIPDQE-AISSSLLASRQADSPMSPSSGSS
RGFSVASMLPDATREDVTNSTS-ANTCDSCTFAEQTDIVALAARAIFDQENLEKGRVGAQ
--ADIQETPPKPSEASSLE--GDQSFKTQTAKESTTGKVEVTANEFNSQDPV---QANVD
--RSLEKPSCSVS-TETSNASIQVSTSQSPSISSLSVNNLIHQSSISHPLVSCS------
EQSTIPATVNLSVSSSSYANQPSE-SSLMTEYSQDQLSTMTNN-VPNSQIQESH-LKSSH
DSRKDPAKRPVQDDLLLSTAKRQKHCQPAPLRLEGMTLMSRTPDSIAEQTQMMVGQIPSN
SSNSVVP--VSNPGHVDDLSRLFPSSNNFVTPALRQPEVQCNSQPSMAEQQ--QSQAGSQ
HLQPLQQH-VPPAQGISHLHNNHPYLKQQQQQ-----------------QQAGQLRDRHH
LYQL-QHHVPHADSSIHSQPHNVHQQRTIQQEVQMQKKRSLVQGTQAPQLSIQQKHHASD
QPRPKGGQPHPHHQQIQQQMQQHFGGSQSEKSCENPSTSRTHH-NHPPNHLNQDIMHQQ-
QDVGTRQQGSGVSSEHVSAHNPMQRLMPPRGLEQ-QMVSQPSIVTRSSDMTCAPHRPERN
RVSSYSAEALIGKTSSNSEQRMGISVQGPRVSDQLEMRSYLDVPRNKGLAIHNMQSRV--
DHTVASD-VRLSDCQTFKPSGASQQPQTNFEVQSSRNNEIGNP-VPSLRGMQSQAFRISQ
NTG-PPIDRQKRLPYPPVQSLPAGNAIPP-RDNENACHQSFMQSLLAPHLGDQVIGNQRS
ISEHQRNSQCGPSSTIEYNCPPGHESIHIRRESESQNRESCDMSLGAINTRNSTLNIPFS
SSSSSGDIQGRNTSPNVSVQKSNPMRMTESHGTKGHMNPPVTTNIHGVARPTLPHPAVSH
GSGDQGPPSVRQPNSSVTQRSRHPLQDGSGGSKIRQPERNRSGNQRHNNVFDPSLPHLPL
STSGSMIIGRQQSSTEKRGSIVRFMPDGPQVPNDSSAPDQHTLSQNFGFPFIPEGGMNPP
INANTSFIPQVTQPSATRTPALIPVDPQNTLPSFYPPYSPAHPTLSNDISIPYFSNQMFP
NPSTEKVNSGGLNNRFGTILSPPRPVGFAQPSFPLLPDMPPMHMTN-SHLSNFNMTSLFP
EIATAL-PDGSAMSPLLTIANSSASDSSKQTSNRPAHNISHILGHDCSSAV

----------------------MPEMTENETPTKKQHRKKNRETHNAVERHRKKKINAGI
NRIGELIPCSPALKQSKNMILDQAFKYITELKRQNDELLLNGGNNEQAEEIKKLRKQLEE
IQKENGRYIELLKANDICLYDDPTIHWKGNLKNSKVSVV---------------------
IPSDQVQKNIIVYSNGNQPGGNSQGIAVQGVTFNVGPNLQKQTASVVPVPRTCNLVTPAS
ISGVYPSENKPWHQTTVPALATNQPVPLCLPATISAQSILELPTSESESSVLGATGGSL-
-IAVSVGPEPHQHRSLHTCLNDQSS---SENKNGQENPKLLKKMSPCTTNIPLSSSATAT
EVHHGSK---SC-LSTQDFRGDVQNTVVVS----VTTTVCAQPPRTAGESS----PVSIS
KSADSTSTATVVASSAP-AVGKATVPVSTLSGNPLDNGWTLSCSLPSSSVSVSDLKNINS
LTRISSAGNTQTTWTTLQLAGNTIHPLSQTPSSAVTPALSESG--TSPTTSNHSRHMATG
I--NLNNSFPADGQPVEQVVVTLPSCPSLPMQPLIAPPQVKSQPPKNILPLNSAMQVIQM
AQPVGSAVNAGPTNQNVIILQPASTTACPTVMRAEVPSQTVGQQIVIIQAA-NQNPLPLL
SAPPPGSVRLPINGANAVIGSNNSVQNVSTPQTFGGKHLVHILPRPSSLS-VSNSTQTFS
VTMSS-QQPQTISLNGQLFALQPVLSSSGTTNQTPMQIIQPTTSEDPNTNVALNTFGALA
SLNQSISQMAGQSCVQLSMSQPANTQTAANSQTTP-NCVSLATTAAPPVATDSSATLAST
YNLVTPSSVNTVAGLPPNVKSKRLTKKPGAKKHLAA-NKSACSLNPVRDVNKLDCPNTEG
SAEPPCN-DGLLESLPAVLP-SVSVSQAN---------SVSVSAS-----HSLGAVSSES
-------------LIPGSASKSKSAEKSSSPSQESVTSEHFAVAPAKSKDSTPNLQQEMS
QGKPPSSSASSDAAKPCTSANVLIPSPSDPHILVSQVSGLPSTTSTTSTDCVSEVEIIAE
PCRVEQDA-SDTMQTAGLLKGQGLTTLLSDLAKKKDPQ--KSSLSDQMDHPDFSSENPK-
LVDSSVNLQP-KQELLLMNNDERDPPQHHPCLPDQE-VIHGSLITSRQADSPMSTSSGSS
RSFSVASMLPETTREDVTSNAT-TNTCDSCTFVEQTDIVALAARAIFDQENLEKGRVGLQ
--ADIREVASKPSEASSLE--GDPPFKSQIPKENGTGQAEATPNEFNSQDSI---EATME
--RPLEKPSCSLG-IKTSNASLQASNPQPPSITSLSVNNLIHQSSVSHPLVSCAGLSPAS
EPTTVPATVNLTISSSSYGSQPPG-PSLITEYSQEQLNTMTST-IPNSQIQEPL-LKPSH
ESRKDSAKRAVQDDLLLSSAKRQKHCQPASLRLESMSLMSRTPDTISDQTQMMVSQLPPN
SSNSVVP--VSNPAHGDGLTRLFPPANNFVAPALRQSEVQCGSQPSV-AEQ--QQTQASQ
HLQALQQH--VPAQGVPHLHSNHLYIKQQQQ----------------QQQQAGQLRERHH
LYPM-QHHVPHAESSVHSQPHNVHQQRTLQQEVQMQKKRNLVQGTQASQLSLQAKHHGTD
QSRSKSGQPHPHHQQLQQQMQQHFGSSQTEKSCENPSATRNHH-NRPQNHLNQDIMHQQ-
QEVGSRQQGSGVSSEHVSGHNPMQRLLTSRGLEQ-QMVSQPSIVTRSSDMTCTPHRPERN
RVSSYSAEALIGKTSSNSEQRMGISIQGSRVSDQLEMRSYLDVPRNKSLAIHNMQGRV--
DHAVASD-IRLSDCQTFKTSGASQQPQSNFEVQSSRNNEIGNP-VSSLRSMQSQAFRISQ
NTGPPPTDRQKRLPYPPVQTIPTGNGIPS-RDSENACHQSFMQSLLAPHLSDQVIGSQRS
LSEHQRNTQCGPSSAIEYNCPPTHENVHIRRESESQNRESCDMSLGAINTRNSTLNIPFS
SSSSSGDIQGRNTSPNVSVQKSNPMRITDSQATKGHMNPPVTTNMHGVARPALPPPSVSH
GNADQGP-PVRQANSSVPQRSRHPLQDS-SGSKIRQPERNRSGNQRQSNVFDPSLPHLPL
PAGGSMILGRQQPAAEKRGSIVRFMPDSSQVPNDNPGPDQHTLSQNFGFSFIPEGGMNPP
INANASFIPQVTQPSATRTPALIPVDPQNTLPSFYPPYSPAHPTLSNDISIPYFSNQMFS
NPSTEKVNSGSLNNRFGSILSPPRPVGFAQPSFPLLPDMPPMHMTN-SHLSNFNMTSLFP
EIATAL-PDGSAMSPLLTIANSSASDSSKQSSNRPAHNISHILGHDCSSAV

----------------------MPEMTEHETPTKKQHRKKNRETHNAVERHRKKKINAGI
NRIGELIPCSPALKQSKNMILDQAFKYITELKRQNDELLLNGGNNEQAEEIKKLRKQLEE
IQKENGRYIELLKANDICLYDDPTIHWKGNLKNSKVSVV---------------------
IPSDQVQKNIIVYSNGSQPGGNSQGTTVQGITFNVGHNLQKQTANVVPVQRTCNLVTPVS
ISGIYPSENKPWHQTTVSALAANQPVPLCLPATISAQNILELPTSESEASVLGATGGSL-
-IAVTVGPEPHQHPSSHTCPNDQNS---SENNSGLDSTKLVKKTSPCLTNVSSSSSATAT
KVHCGTK---SC-LSLQNCRGDLQNTFVVS----VTTTVWSQPPKPAGNPS----PLSIS
KCTDSTNITTVVASSVP-GVGKTTSPVSTLSTNPLDSSWTLSCSLPSSSASASDLKNINS
LTRISSAGNTQTTWTTLQLAGNTIQPLSQTPSSTVTPVLSECG--TSPTTSNHSRHVTTG
I--SLNNSLPADGQPVEQVVVTLPSCPPLPMQPLISQPQVKSQPPKNLLPLNSAMQVIQM
AQPVAPAVNGASANQNVIILQPPSTTPCPTVMRAEVPNQTVGQQIVIIQAA-NQNPLSLL
SAPPPGSVRLPVNGASAIVGSSNSVQNVSTPQTFGGKHLVHILPRPSSLS-TSSSTQTFS
VTMSNQQQPQTISLNGQLFALQPVMSSSATTSQTPMQIIQPTTSEDPNTNVALNTFGALA
SLNQSISQMAGQSCVHLSISPSANPQTAANSQTSPANCVSLTAGIAPPMTTDNSATLPST
YSLVTT-SVNTTACLPPAMKSKRLTKKPGAKKHLAA-SKPACPLNPVREVGKLDRPRPEG
SVEPPCH-DGLLESLPVVLP-SVTVSEAN--------N-V-----SVSASHSLDVLNSET
-------------VMPESVSKSKSAEASSSPCQESVTSEHFAASPEKSKDSVPILEQETS
QDRPPTSLALSDATKSCTSANALIPSPGDSQVLVSQVSGLSSTTSTTNTDCVSEVEIITE
PCRIEQSS-SDTMRAAGLLKGQGLTTLLSDLAKEKDPQ--KLSLSVQIDHPDFSSENSK-
VVDSTVDLHP-KQELLLVNSEDSDPPQQHSCLPDQE-VMNGSLL-ARQADSPMSTSSGSS
RSFSVASMLPETTREDVTSTTT-TNTCDSCTFVEQTDIVALAARAIFDQENIEKGRAGIQ
--ADMREVTSKSSEESSLE--GDQPFKSHIPKETDTGQGETTASEYNSQDSV---EVTGE
--RPLQKPSCSLG-IKTSNASLQTASSQPPSLTSLS-------SSITHPLVSCTGLSQTS
DQTTVPTTVNLTVSSSSYGSQPPG-PSLMTEYPQEQLNTMAST-IPNSQIQEPL-LKPNH
ENRKDSTKRAVQDDLLLSSAKRQKHCQPTPLRLENMSLMSRTPDSISDQAQMMVSQIPPN
SSNSVVP--VSNPAHGDGLTRLFPPGNNFVTSALRQTEVQCSSQPSV-AEQ--QQTQASQ
HLQALQQH--VPPQGVSHLHSNHLYIKQQQQ------------------QQAGQLRERHH
LYQL-QHHVPHAENAVHSQPHNVHQQRTLQQEVQMQKKRNLVQGTQSSQLSLQPKHHATD
QSRTKSGQPHPHHQQMQQQIQQHFASSQPEKSCENPSTSRNHH-SHPQNHLNQEIMHQQ-
QDVGSRQQGSGVSSEHVSGHNPMQRLLTSRGLEQ-QMVSQPSIVTRSSDMTCTPHRTERN
RVSSYSAEALIGKTSSNSEQRMGIPIQGSRVSDQLEMRSYLDVPRNKSLAIHNMQGRI--
DHTVASD-IRLSDCQTFKPSGASQQPQSNFEVQSSRNNEIGNS-VSSLRSMQSQAFRISQ
NTGPPPIDRQKRLPYPPVQSIPTGNAIPP-RDSENTCHQSFMQSLLAPHLGDQVIGSQRS
LSEHQRNTQCGPSSAVEYNCPPTHESIHIRRDSESQNRESCDMSLGAINTRNSTLNIPFS
SSSSSGDIQGRNTSPNVSVQKSNPMRITDSHGTKGHMNPPVTTNMHGVARPALPHPSVSH
GNAEQGP-PVRQANTSVPQRSRHPLQDS-GSSKIRQPERNRSGNQRHSNVFDPSLPHLPL
STSGSMILGRQQPATEKRGSIVRFMPDSPQVPNDNSGPDQHSLSQNFGFPFIPEGGMNPP
INANTSFIPQVTQPSATRTPALIPVDPQNTLPSFYPPYSPAHPTLSNDISIPYFSNQMFS
NPTTEKVNSGSLNNRFGSILSPPRPVGFAQPSFPLLPDMPPMHMTN-SHLSNFNMTSLFP
EIATAL-PDGSAMSPLLTIANSSASDSSKQSSNRPAHNISHILGHDCSSAV

----------------------MPEMTENETPTKKQHRKKNRETHNAVERHRKKKINAGI
NRIGELIPCSPALKQSKNMILDQAFKYITELKRQNDELLLNGGNNEQAEEIKKLRKQLEE
IQKENGRYIELLKANDICLYDDPTIHWKGNLKNSKVSVV---------------------
IPSDQVQKNIIVYSNGSQPGGNSQGTAVQGITFNVGHNLQKQTANVVPVQRACNLVTPVS
ISGVYPSENKPWHQTTVSALAANQPVPLCLPATISAQNILELSTSESESSVLGATGGSL-
-ITVPIGPEPHQHHSLHTCLNDQNS---SENKNGQESPKLLKKTVPCATSIPSSSSATAI
KVHHGSK---SC-LSIQDFRSDFQTTFVVS----VATTVCSQPPRSAGDSC----PSSIG
KGADTTSVTAVVAPSAP-GGGKTTTPVSSLSANPLDNVWTLSCSLPSSAVSASDLKNINS
LTRISSAGNTQTTWTTLQLAGNTIQPLSQTPSSTVTPVLNESG--TSPTTTNPSRHVATG
I--NLNNSFPGDGQPVEQVVVTLPSCPSLPMQPLIAQPQVKSQPPKNILPLNSAMQVIQM
AQPVGSAVNAAPANQNVIILQPPSTTPCPAVMRAEVPNQTVGQQIVIIQAA-NQNPLPLL
SAPPPGSVRFPVNGANAIIGSNNSVQNVSTPQTFGGKHLVHILPRPSSLS-TSNSTQTFS
VTMSNQQQPQTISLNGQLFALQPVMSSSGTTNQTPMQIIQPTTSEDPNTNVALNTFGALA
SLNQSISQMAGQSCVQLSIGQPANPQTAANSQTTPANSVSLTTTIAPPMTTENSATLPTT
YNVVTTPSVNTAACLP-NMKSKRLNKKPSVKKHLAA-SKSVCPQNPVRDVGKLDCPSAEG
SAEPSCS-DELLGSLPVVLP-SVAVSQEN---------SVNVSGS-----HSLDVLSSEP
-------------VIPESVPKSKSAEESSSPSQESVTSEHFAVAPAKPKDSAPILQRETS
QDKPPTSFALSDAAKSCPSAHVLIPSPNDPHILVSQVSGLSSTTSTTNTDCVSEVEIIAE
PCRVEQDS-SATMQTTSLLKGQGLTALLSGLAKEKDPQ--KSSLPVQVDHSDFSSENSK-
IVDSSVDLHP-KQELLLLNSDDRDPGQHHSCLPDQE-VINGSLLTSRQADSPMSTSSGSS
RSFSVASMLPETTREDVTINTT-TNTCDSCTFVEQTDIVALAARAIFDQENLEKGRAGTQ
--ADIREVTSKPPEASSLE--GDQPFKTQVSKETDPGQAEATPNEFNSQDSV---EATVD
--RPLEKPSCSIG-IKTSNASLQVSTSQPSSITSLSVNNLIHQSSISHPLVSCAGLSQTS
EQTTVPATVNLTVASSSYGGQPPG-PSLMTEYSQEQLNPMTAT-IPNPQIQESL-LKPSH
ESRKDSAKRAVQDDLLLSSAKRQKHCQPAPLRLEGMSLMSRTPDSISDQTQMMVSQIPPN
SSNSVVP--ISNPAHGDGLTRLFPPSNNFVAPALRQTEVQCSSQPSV-AEQ--QQTQATQ
HLQALQQH--VPAQGVSHLHSNHLYLKQQQQQQ--------------QQQQAGQLRERHH
LYQL-QHHVPHAESSGLSQPHNVHQQRTLQQEVQMQKKRNLVQGTQASQLSLQPKHHGTD
QARSKSGQPHPHHQQMQQQMQQHFGSSQPEKSCENPSTSRSHH-NHPQNHLNQDIMHQQ-
QDVGSRQQGSGVSSEHVSGHNPMQRLLTSRGIEQ-QMVSQPSIVTRPSDMTCAPHRPERN
RVSSYSAEALIGKTSSNSEQRMGISIQGSRVSDQLEMRSYLDVPRNKSLAIHNMQSRV--
DHTVASD-IRLSDCQTFKPSGASQQPQSNFEVQSSRNNEIGNP-VSSLRSMQSQAFRISQ
NPGPPSIDRQKRLPYPPVQSIPTGNAIPP-RDSENTCHQSFMQSLLAPHLGDQVIGSQRS
LSEHQRNTQCGPSSAIEYNCPPTHESVHIRRESDSQNRESCDMSLGAINTRNSTLNIPFS
SSSSSGDIQGRNTSPNVSVQKSNPMRITDSHGTKGHMNPPVTTNMHGVARPALPHPSVSH
GNADQGP-PVRQTNSSVPQRSRHLLQDS-SGSKIRQPERNRSGNQRHSNVFDPSLPHLPL
STSGSMILGRQQPTTEKRGSIVRFMPDSPQVPNDNSAPDQHTLSQNFGFPFIPEGGMNPP
INANTSFIPQVTQPSATRTPALIPVDPQNTLPSFYPPYSPAHPTLSNDISIPYFSNQMFS
NPSTEKVNSGSLNNRFGSILSPPRPVGFAQPSFPLLPEMPPMHMTN-SHLSNFNMTSLFP
EIATAL-PDGSAMSPLLTIANSSASDSSKQSSNRPAHNISHILGHDCSSAV

----------------------MPEMTQNNTPPKAKHRKKNRESHNEVERHRKKKINSGI
NRIGDLIPCSPALKQSKNMILEQAYKYITELKRQNDELLLNGGDKEQSIEIKRLRKDLAE
IQKENARYIELLKSNDICLYDDPTLHWKGNNKNPKASVV---------------------
VPAEQAQKPLC--LGGNQQGSNNSPAAAHGISFNAGNNLQKQTANVVPVQRTCNIVTPIT
ISGVSLLEGKAWQQSATSITSSNQQASLCLPLTSSAPITVGITTSERS--VLVPISSAPH
PLLDSA-ASQIPCSSGQTSLHGQNRVQGSENATHQESLP--KVPSSISSSLPSSLSSFVP
EVPLV---SVSG-ISLQECPSLLQGQLLGAAGCAVKDVIQEIFPTVSTDSS-----LQVA
-----NSSREVLATPADIAGG----STLGNSSAPLESSWSLSA------LPSRELKSVGS
LARVPSDGNTQTTWTTLQVAGSTIQPLSQAPPGVVPMLVTEQRLCP--------KEPTPC
V--NLNSFASDAGKPVEQVVVKMSSCQPVQVQSLISQPQS----ATNILPLNQPVQVIQV
AQPVAPAVNPAPANQNIIFLQPPAPAPCTPVIRAEVPKPTIGQQIVIIQAAPNQNPLPLM
PTQPTPPVVVPLNPASSVACPSNTVQSSAPPQTFGGKHLVHILPRPTTLVTPSTTQSVPT
STASSNQQPPTISLNGQLFALQPVTPSAGTSSQTHMQIIQPTTSEDPNTNVALNTFGALA
NLSQSISQIAGQSCLQFTVNPSAASL---PSTSIPLSCVSTSGAST---TTESPSIT---
SAPTKTASAKPVGGSP-SAKAKKPIKKANAKKSASS-RKEDIPFT------KSD------
KPESSCI-----ESAPLPSSGEVQKRQDNVYVVTSAPENTNVSDIHLPKANSTDSTQ-EI
STLAVLNSGVEERLLPESREQYSSGFSSTRDG-SSTTDTCITRIPGS-------------
--------ASSESLKSL-AVTNIPPEPVCPQPMHDTSVRECTTQAGESTDRPTQVFTSSD
CCVSEMN--SAALTATDLLEAQIL----SDDPKGKSLSVAESTKEMVGDELIYRKDKSK-
-----ESVEQVKQDVSVLPMAAGSVSQHQSNTAEQEMGVCSSVVTSRQTDSPMSTSSSSS
RNFSVASMLPNTNREDVTTNAPPAPEFTGCPFAEQSDIVAVAARAIFEQENLAKGRPRLQ
PET--PGPVPSNANAALLAADCRNQYKAQADKESFVQ-LPAKSTSFTALN---A-NPVPA
SDRMEEKNNCPMG-IN--TTNLQIPSSQSQNGTSLSINNLIQHGGTTHSIVNFANASRTS
EQVTLPTSSKLLLPSGSYESQAHRSAAALPEYSQGQLHSMKTTIMQVTHTTESL-LKQSD
EHRKDSNKRSAHEDGLLSTAKRQKQCQ-APLRLERI----QPPDGLGEQNEILVSHVPSN
TSSSVP---GVNAVHEDGLGTLFPSSNSFI----RQSELRCSSQASVSEHQQG--QMVSQ
HL--IQQHP-PPNHQGSLHHSSVPYLKQQQQQ-----------------QQANHLREQHH
LYQQQQHHVAHAESAVHSQSRSV-QQRLIQQDVQMQKKQASIQSSQATRM---------S
QNHPKGAQTHSHHQQIQQQMQSHFGPSQADKTCENATANRSHRGTHPQSHVSQDILHQHP
QDVGSRTQGPPVSSEHLPSHSQVQRLMTSRSLEQ-QLVSQPSIISRPTNMACTPHRQERN
RVSSYSAEALIGKSTSNSDQRMGISAQASRVSEQHEMRKYLDISRNKGLAVHNVQGQLSI
EHPINADAQRLPDCQSFKAGGSSQQQRGSFDTQTSRPNDVNT--VPSMRGMQAQAYRITQ
NPNL-SMDQQKHLSYQPGPEVSLSNALPI-RDNDNSCHQSFMQSLLTPHIGEQVGVGQRL
ISSNQRNAQYNAVSAVEYGCPAARDAVHLRRDGDGQNRESCDLAIAQVTSRSHSLSIPFS
GSTSSVEIPGRSSSPNASMQKS--MRPNETQGAKNHLNIQVSINMHGVVHPTLPQQSVSH
NNQN-----VRLPNPPVTQRSRHLLQDD-GDSKSRQPERNRLANQRHSNMFEPALPHLPL
TGPSSMILGRQQTVNDKRPGIVRFMPDNGQVSGDNSG-DQHSLTQNFGFPFIPEGTMNPP
INANASFIPPVTQAAATRTPALIPVDPQNTLPSFYPPYSPAHPSLSNDITIPYFPNQMFP
NPSTEKPNSAGLNNRFGTILSPPRPVGFSQTTFPLLPDMPPMHMANPSHLSNFNLTSLFP
EIATALPTDGSAMSPLLSISHSSGSDSSKQ--NRPAHNISHILGHDSSSAV

----------------------MPEMTENETPTKKQHRKKNRETHNAVERHRKKKINAGI
NRIGELIPCSPALKQSKNMILDQAFKYITELKRQNDELLLNGGNNEQAEEIKKLRKQLEE
IQKENGRYIELLKANDICLYDDPTIHWKGNLKNSKVSVV---------------------
IPSDQVQKNIIVYSNGNQPGGNSQGTAVQGITFNVSHNLQKQTANVVPVPRTCNLVTPVS
ISGVYPSENKPWHQTTVPALATNQPVPLCLPATISAQSILELPTPESESSVLGATGGSL-
-IAVSIGPEPHQHRSLHTCLNDQNS---SENKNGQENPKLLKKMAPCATNIPLSSSATAT
EVHHGNK---SC-LSIQDFRGDVQNTFVVS----VTTTVCSQPPRTSGDSS----PVSIS
KSADSTSTATVVASSAP-GVGKATIPVSTLSGNPLDNGWTLSCSLPSSSVSASDLKNINS
LTRISSAGNTQTTWTTLQLAGNTIQPLSQTPSSAVTPVLSESG--TSHTTSNHSRHMATG
I--NLNNSFPADGQPVEQVVVTLPSCPSLPMQPLIAQPQVKSQPPKNILPLNSAMQVIQM
AQPVGSAVNAAPTNQNVIILQPPSTTPCPTVMRAEVPNQTVGQQIVIIQAA-NQNPLPLL
SAPPPGSVRLPINGANAVIGSNNSVQNVSTPQTFGGKHLVHILPRPSSLS-MSNSTQTFS
VTMSS-QQPQTISLNGQLFALQPVMSSSGTTNQTPMQIIQPTTSEDPNTNVALNTFGALA
SLNQSISQMAGQSCVQLSISQPANTQTAANSQTTPANCVSLTTTAAPPVTTDSLATPAST
YNLVTTSSVNTVACLPPNMKSKRLNKKPGAKKHLAA-NKSACSLNPVRDVSKLDCPNTEG
SAEPPCN-DGLLESLPAVLP-SVSMSQAN---------SVSVSAS-----HSLGVVSSES
-------------LIPESASKSKSAEKSSSPSQESVTSEHFAMAPAKSKDSTPNLQQEVS
QDKPPSSLALSDAAKPCTSANVLIPSPSDPHILVSQVSGLSSTTSTTSTDCVSEVEIIAE
PCRGEQDS-SDTMQTTGLLKGQGLTTLLSDLAKKKNPQ--KSSLSDQMDHPDFSSENPK-
IVDSSVNLHP-KQELLLMNNDERDPPQHHPCLPDQE-VIHGSLITGRQADSPMSTSSGSS
RSFSVASMLPETTREDVTSNAT-TNTCDSCTFVEQTDIVALAARAIFDQENLEKGSVGLQ
--TDIREVASKPSEASSLE--GDPPFKSQITKENGTGQAEATPNEFNSQDSI---EATME
--RPLEKPSCSLG-IKTSNASLQASNPQPPSITSLSVNNLIHQSSISHPLASCAGLSPTS
EQTTVPATVNLTISSSSYGSQPPG-PSLMTEYSQEQLNTMTST-IPNSQIQEPL-LKPSH
ESRKDSAKRAVQDDLLLSSAKRQKHCQPAPLRLESMSLMSRTPDTISDQTQMMVSQIPPN
SSNSVVP--VSNPAHGDGLTRLFPPANNFVAPALRQAEVQCGPQPSV-AEQ--QQTQASQ
HLQALQQH--VPAQGVSHLHSNHLYIKQQQQQQQQQ--------QQQQQQQAGQLRERHH
LYQM-QHHVPHAESSVHSQPHNVHQQRTLQQEVQMQKKRNLVQGTQASQLSLQPKHHGTD
QSRSKSGQPHPHHQQLQQQMQQHFGSSQTEKSCENPSTTRNHH-NHPQNHLNQDIMHQQ-
QEVGSRQQGSGVSSEHVSGHNPMQRLLTSRGLEQ-QMVSQPSIVTRSSDMTCTPHRPERN
RVSSYSAEALIGKTSSNSEQRMGISIQGSRVSDQLEMTSYLDVPRNKSLAIHNMQGRV--
DHTVASD-IRLSDCQTFKPSGASQQPQSNFEVQSSRNNEIGNP-VSSLRSMQSQAFRIGQ
NTGPPPTDRQKRIPYPPVQSIPTGNGIPS-RDSENTCHQSFMQSLLAPHLSDQVIGSQRS
LSEHQRNAQCGPSSAIEYNCPPTHENVHIRRESESQNRESCDMSLGAINTRNSTLSIPFS
SSSSSGDIQGRNTSPNVSVQKSNPMRITDSQATKGHMNPPVTTNMHGVARPALPHPSVSH
GNADQGP-PVRQANSSVPQRSRHPLQDS-SGSKIRQPERNRSGNQRQSNVFDPSLPHLPL
SAGGSMILGRQQPATEKRGSIVRFMPDSPQVPNDNSGPDQHTLSQNFGFSFIPEGGMNPP
INANASFIPQVTQPSATRTPALIPVDPQNTLPSFYPPYSPAHPTLSNDISIPYFSNQMFS
NPSTEKVNSGSLNNRFGSILSPPRPVGFAQPSFPLLPDMPPMHMTN-SHLSNFNMTSLFP
EIATAL-PDGSAMSPLLTLANSSASDSSKQSSNRPAHNISHILGHDCSSAV

----------------------MPEMTENETPTKKQHRKKNRETHNAVERHRKKKINAGI
NRIGELIPCSPALKQSKNMILDQAFKYITELKRQNDELLLNGGNNEQAEEIKKLRKQLEE
IQKENGRYIELLKANDICLYDDPTIHWKGNLKNSKVSVV---------------------
IPSDQVQKKIIVYSNGNQPGGNSQGTAVQGITFNVSHNLQKQTANVVPVQRTCNLVTPVS
ISGVYPSENKPWHQTTVPALATNQPVPLCLPAAISAQSILELPTSESESNVLGATSGSL-
-IAVSIESEPHQHHSLHTCLNDQNS---SENKNGQENPKVLKKMTPCVTNIPHSSSATAT
KVHHGNK---SC-LSIQDFRGDFQNTFVVS----VTTTVCSQPPRTAGDSS----PMSIS
KSADLTSTATVVASSAP-GVGKATIPISTLSGNPLDNGWTLSCSLPSSSVSTSDLKNINS
LTRISSAGNTQTTWTTLQLAGNTIQPLSQTPSSAVTPVLNESG--TSPTTSNHSRYVATD
I--NLNNSFPADGQPVEQVVVTLPSCPSLPMQPLIAQPQVKSQPPKNILPLNSAMQVIQM
AQPVGSAVNSAPTNQNVIILQPPSTTPCPTVMRAEVSNQTVGQQIVIIQAA-NQNPLPLL
PAPPPGSVRLPINGANTVIGSNNSVQNVPTPQTFGGKHLVHILPRPSSLS-ASNSTQTFS
VTMSN-QQPQTISLNGQLFALQPVMSSSGTTNQTPMQIIQPTTSEDPNTNVALNTFGALA
SLNQSISQMAGQSCVQLSISQPANSQTAANSQTTTANCVSLTTTAAPPVTTDSSATLAST
YNLVSTSSMNTVACLP-NMKSKRLNKKPGGRKHLAA-NKSACPLNSVRDVSKLDCPNTEG
SAEPPCN-DGLLESFPAVLP-SVSVSQAN---------SVSVSAS-----HSLGVLSSES
-------------LIPESVSKSKSAEKSSPPSQESVTSEHFAMAAAKSKDSTPNLQQETS
QDKPPSSLALSDAAKPCASANVLIPSPSDPHILVSQVPGLSSTTSTTSTDCVSEVEIIAE
PCRVEQDS-SDTMQTTGLLKGQGLTTLLSDLAKKKNPQ--KSSLSDQMDHPDFSSENPK-
IVDSSVNLHP-KQELLLMNNDDRDPPQHHSCLPDQE-VINGSLINGRQADSPMSTSSGSS
RSFSVASMLPETTREDVTSNAT-TNTCDSCTFVEQTDIVALAARAIFDQENLEKGRVGLQ
--ADIREVASKPSEASLLE--GDPPFKSQIPKESGTGQAEATPNEFNSQGSI---EATME
--RPLEKPSCSLG-IKTSNASLQDSTSQPPSITSLSVNNLIHQSSISHPLASCAGLSPTS
EQTTVPATVNLTVSSSSYGSQPPG-PSLMTEYSQEQLNTMTST-IPNSQIQEPL-LKPSH
ESRKDSAKRAVQDDLLLSSAKRQKHCQPAPLRLESMSLMSRTPDTISDQTQMMVSQIPPN
SSNSVVP--VSNPAHGDGLTRLFPPSNNFVTPALRQTEVQCGSQPSV-AEQ--QQTQASQ
HLQALQQH--VPAQGVSHLHSNHLYIKQQQQQQQQQ-------QQQQQQQQAGQLRERHH
LYQM-QHHVPHAESSVHSQPHNVHQQRTLQQEVQMQKKRNLVQGTQTSQLSLQPKHHGTD
QSRSKTGQPHPHHQQMQQQMQQHFGSSQTEKSCENPSTSRNHH-NHPQNHLNQDIMHQQ-
QDVGSRQQGSGVSSEHVSGHNPMQRLLTSRGLEQ-QMVSQPSIVTRSSDMTCTPHRPERN
RVSSYSAEALIGKTSSNSEQRMGISIQGSRVSDQLEMRSYLDVPRNKSLAIHNMQGRV--
DHTVASD-IRLSDCQTFKPSGASQQPQSNFEVQSSRNNEIGNP-VSSLRSMQSQAFRISQ
NTGPPPIDRQKRLSYPPVQSIPTGNGIPS-RDSENTCHQSFMQSLLAPHLSDQVIGSQRS
LSEHQRNTQCGPSSAIEYNCPPTHENVHIRRESESQNRESCDMSLGAINTRNSTLNIPFS
SSSSSGDIQGRNTSPNVSVQKSNPMRITESHATKGHMNPPVTTNMHGVARPALPHPSVSH
GNGDQGP-AVRQANSSVPQRSRHPLQDS-SGSKIRQPERNRSGNQRQSTVFDPSLPHLPL
STGGSMILGRQQPATEKRGSIVRFMPDSPQVPNDNSGPDQHTLSQNFGFSFIPEGGMNPP
INANASFIPQVTQPSATRTPALIPVDPQNTLPSFYPPYSPAHPTLSNDISIPYFPNQMFS
NPSTEKVNSGSLNNRFGSILSPPRPVGFAQPSFPLLPDMPPMHMTN-SHLSNFNMTSLFP
EIATAL-PDGSAMSPLLTIANSSASDSSKQSSNRPAHNISHILGHDCSSAV

----------------------MPEMTENETPTKKQHRKKNRETHNAVERHRKKKINAGI
NRIGELIPCSPALKQSKNMILDQAFKYITELKRQNDEFLLNGGNNEQAEEIKKLRKQLEE
IQKENGRYIELLKANDICLYDDPTIHWKGNLKNSKVSVV---------------------
IPSDQIQKNIIVYSNGSQPGGNSQGAAVQGITFNVGHNLQKQTANVVPVQRTCNLVTPVS
ISGVYPSENKPWHQTTVSALAANQPVPLCLPATIPAQNILKLATSKSDSRVLGATRGSL-
-VAVPIGPEPCQHRSLHTSVNDQNS---SENKNGKENPKLLKKTVPCATSVPSSSSATTT
KVNPGDK---SC-LSTQDLRSDFQTTFVVS----VTTTVCSQPPRSAGDPG----PVSIS
KGADSASVTAVVAPSVP-GGGKTTAPVSSPSANPLDNGWTLSCSLPSSAVSASDLKNINS
LTRISSSGNTQTTWTTLQLAGNTIQPLSQTPSSAVTPVLNESG--TSPTTSKHGRHMATS
I--NLNNSFPADGQPVEQVVVTLPSCPSLPMQPVIAQPQVKSQTPPNILPLNSAMQVIQM
AQPVGTAVKAAPANQNVIILQPPSTTPCPTVMRAEVPNPTVGQQIVIIQAA-NQNPLPLL
SAPPPGSVRLPVNGANAIIGSN-SVQNVPTPQTFGGKHLVHILPRPSSLS-TSNSTQTFS
VTMSNQQQPQTISLNGQLFALQPVMSSSGTTNQNPMQIIQPTTSEDPNTNVALNTFGALA
SLNQSISQMAGQSCVQLSISQPGNPQTTASSQTTPANCASLTATVASPMTTDTSATLPST
YNLVTTPSVNTVACLP-NVKSKRLNKKPGVKKHLAA-NKSACPLNPVSNVGQVDCPSTEG
SAEPPCN-DGLLESPPLVVP-SVTMSQAE--------STVSVSGS-----PSLDVPNSES
-------------VIPESVPKSKSAEESNSPCQESITSEHFVVAPAKSKDSVPIVQRETS
QDKPPTSLALSDAPKFGTSANVLIPSPNDPHVLVSQVSGSSSTTSTTSTDCVSEVEIIAE
PCGVEQDS-SDRMQTTGLLKEQGLTALLSGLAKEKDPQ--KSSLSVQVDHPDFSSENSK-
IIDSSIDLHS-KQELLLMNSDDRDPGQHHSCIPDQE-IIHGSLLTSRQADSPMSTSSGSS
RSFSVASMLPETTREDVTSNVT-TNTCDSCTFVEQTDIVALAARAIFDQENLEKGKAGTQ
--ADTREVTSKPSEASSLE--GDQPFKTQVSKENSPGQAEATPNEFSSQDSI---EATVD
--RPLEKPSCSVG-IKTSNASLQVSNSQPPSITSLSVNNLIHQSSISHSLVSCAGLSQTS
ESTTVSATVNLTVSSSSYGGQPPG-PSLMTEYSQEQLSTMTGT-VPTSQIQEPL-LKPSH
ESRKDSAKRAVQDDLLLSSVKRQKHCQPAPLRLEGMSLVSRTPDSISDHTQMMVSQIPPN
SSNSVVP--ISNPAHGDGLTRLFPPSNNFVAPALRQTEVQCNSQPSV-AEQ--QQTQASQ
HLQVLQQH--VPAQGVSHLHSNHLYLKQQQQQQ-------------QQQQQAGQLRERHH
LYQL-QHHIPHAESSVHSQPHNVHQQRTLQQEVHMQKKRNLVQGTQASQLSLQPKHHGTD
QSRPKSGQPHPHHQQIQQQMQQHFGSSQSEKSCENPSTSRNHP-NHPQNHLNQDIMHQQ-
QEVGSRQQGSGVSSEHVSAHNPMQRLLTSRGIEQ-QMVSQPSIVTRPSDMTCTPHRPERN
RVSSYSAEALIGKTSSNSEQRMGISIQGSRVSDQLEMRSYLDVPRNKSLALHNMQGRV--
DHTVASD-IRLSDCQTFKPTGAIQQPQSNFEVQSSRNNEIGNS-VSSLRSMQSQAFRISQ
NPGPPPIDRQKRLPYPPVHSIPTGNAIPP-RDSENTCHQSFMQSLLAPHLGDQVIGSQRS
LSEHQRNTQCGPSPAVEYNCPPTHESVHIRRESENQNRESCDMPLGAINTRNSTLNIPFS
SSSSSGDIQGRNTSPNVSVQKSNPMRITDSHGTKGHMNPPVTTNMHGVARPALPHPSVSH
GNSDQGP-PVRQTNSSVPQRSRHPLQDS-SGSKIRQPERNRSGNQRHSNVFDPSLPHLPL
SASGSMILGRQQPTTEKRGSIVRFMPDSPQVPNDNSAPDQHTLSQNFGFPFIPEGGMNPP
INANTSFIPQVTQASATRTPALIPVDPQNTLPSFYPPYSPAHPTLSNDISIPYFSNQMFS
NPSTEKVNSGSLNNRFGSILSPPRPVGFAQPSFPLLPDMPPMHMPN-SHLSNFNMTSLFP
EIATAL-PDGSAMSPLLTIANSSASDSSKQSSNRPAHNISHILGHDCSSAV

----------------------MPEMTENETPTKKQHRKKNRETHNAVERHRKKKINAGI
NRIGELIPCSPALKQSKNMILDQAFKYITELKRQNDELLLNGGNNEQAEEIKKLRKQLEE
IQKENGRYIELLKANDICLYDDPTIHWKGNLKNSKVSVV---------------------
IPSDQVQKNIIVYSSGSQPGGNNQGAAVQGITFNVGHNLQKQTANVVPVQRTCNLVTPVS
ISRVYPSENKPWHQTTVSALATNQPVPLCLPATISAQNILELSTSESESSVHGATTSSL-
-IAVPLGPELHQHRSLHTCLNDQNS---SENKNRQESPKLLKKTTSCSTSIPPGSSAVAT
EVHHGNK---SC-LSIQDFRGDFQNTFVVS----VSTTVCSQAPRSAGNSS----PVSIS
KTASLTSATTVVAPSAP-GVGRTTTPVSSLSANSLDSGWILSCSLPSSSVSASDLKNINS
LTRISSAGNTQTTWTTLQLAGNTIQPLSQTPSSAVTPVLNESG--TNTTISNHNRHVAAG
I--NLNNSFPADGQPVEQVVVTLPSCPSLPLQPLIAQPQVKSQPPKNILPLNSAMQVIHM
AQPVGPTVNAAPANQNVIILQPPSTTPCPTVMRAEVPNQTVGQQIVIIQAA-NQNPLPLL
SAPPPGSVRLPVNGANAIIGSNNSAQNVSTPQTFGGKHLVHILPRPSSLS-TSNSTPTFS
VTMSNQQQPQTISLNGQLFALQPVMSSSGTTNQTPMQIIQPTTSEDPNTNVALNTFGALA
SLNQSISQMAGQSCVQLSISQPANPQTAANSQPPSANCVSLT-TVAPLTTTDNSASLPST
YNLVTTPSVNTVACLPPNVKSKRLNKKPGAKKHLAA-NKSACPLNPVRDVSKLDCPSAGS
SAEPSCS-DRLLESLPVVLP-SVPVSQAN---------CVSVSAS-----HSLDGLNSES
-------------VTPESVSKCKSAEESGSPSQESVTSEHFAMAPAKSKDCTPNLQRETS
QDK-PTSLALSDAAKSCPSDSVLIPSPNDPHILVSQVSGLSSTTSTTSTDCVSEVEIIAE
PCRVEQDS-SDTMQTTGLLKGQGLTTLLSDLAKEKDPQ--KSSLSDQMSHPDFSSENSK-
IVDSSVNLQH-KQELLLMGSDDRDPAQHHSCLPDQE-VINGSLMPSRQTDSPMSTSSGSS
RSFSVASMLPETTREDVTSSTT-TNTCDSCTFVEQTDIVALAARAIFDQENLEKARVGLQ
--ADVREVTSKPSEASSLE--GDPPFKSQTPKEKGTGQAEVTSDEFHSQDSV---EAAVD
--RPLEKPSCSLG-IKTSNASLQASTSQPPSITSLSVNNLIHQNSISHPLVSCVGLSQTS
EQTTVPTTVNLTVSSSSYGNQPPG-PPLMTEYSQEQLNTMTSN-IPNSQIQEPL-LKPSH
ESRKDSAKRAVQDDLLLSSAKRQKHCQPAPLRLESMSLMSRTPDSISDQTQMMVGQIPPN
SSNSVVP--VSNPAHGEGLARLFPSGNNFVAPALRQTEVQCSSQPSV-AEQ--QQTQASQ
HLQALQQH--VPVQGVSHLHSNHLYIKQQQQ------------------QQAGQLRERHH
LYQL-QHHVPHADSSVHSQPHNVHQQRTLQQEVQMQKKRNLVQATQASQLSLQPKHHATD
QSRPKSGQPHPHHQQMQQQMQQHFGSSQPEKSCENPSASRNHH-SHPQNHLNQDIMHQQ-
QDVGSRQQGSGVSSEHVSGHNPMQRLLTSRGLEQ-QMVSQPSIVTRPSDMTCTPHRPERN
RVSSYSAEALIGKTSSNSEQRMGISIQGSRVSDQLEMRNYLDVPRNKSLAIHNMQGRV--
DHTVASD-IRLSECQTFKPSGASQQPQSNFEVQSSRNNEIGNP-VPSLRSMQSQAFRVSQ
NTGPPPIDRQKRLTYPPVQGIPTGNAVPP-RDSENACHQSFMQSLLAPHLGDQVIGSQRP
LSEHQRNTQCGPSSAIEYNCPPAHESVHIRRESENQNRESCDMSLGAINTRNSTLNIPFS
SSSSSGDIQGRNTSPNVSVQKSNPMRITDSHGTKGHMNPPVTTNMHGVARPALPHPSVSH
GNADQGP-PVRQANSSVPQRSRHPLQDS-SGSKIRQPERNRSGNQRHSNVFDPSLPHLPL
STSGSMILGRQQPAAEKRGSIVRFMPDSPQVPNDNSGPDQHTLSQNFGFPFIPEGGMNPP
INANTSFIPQVTQPSATRAPALIPVDPQNTLPSFYPPYSPAHPTLSNDISIPYFSNQMFS
NPSTEKVNSGSLNNRFGSILSPPRPVGFAQPSFPLLTEMPPMHMTN-SHLSNFNMTSLFP
EIATAL-PDGSAMSPLLTIANSSASDSSKQSSNRPAHNISHILGHDCSSAV

----------------------MPEMTEHETPTKKQHRKKNRETHNAVERHRKKKINAGI
NRIGELIPCSPALKQSKNMILDQAFKYITELKRQNDELLLNGGNNEQAEEIKKLRKQLEE
IQKENGRYIELLKANDICLYDDPTIHWKGNLKNSKVSVV---------------------
IPSDQVQKNIIVYSSGSQPGGNSQGTAVQGITFNVGHNLQKQTANVVPVQRTCNLVTPAS
VSGIYPSEKKPWHQTTVSALAANQPVPLCLPAAISAQNILELSTSESESSVLGASGGSL-
-IAVSVGPELHQYPSSHICTNDQNS---SENNSGLDSTKLLKKTAPCVTSVSPSSSATTT
KVHHGIK---SC-LSLQNCRGDFQNTFVVS----VTTTICSQPPRSSGDSS----PLSIS
KCTDSTNKTTVVAPSAP-SVGKITTPVSTLSANPLDNGWTLSCSLPSSSASASDLKNINS
LTRISSAGNTQTTWTTLQLAGNTIQPLSQTPSSTVTPVLSESS--TSPPTSNHSRHVATG
I--NLNNSLPADGQPVEQVVVTLPSCPPLPMQPLISQPQVKSQPPKNILPLNSAMQVIQM
AQSVGSAVNAASANQNVIILQPPSTTPCPTVMRAEVPNQTVGQQIVIIQAA-NQNPLPLL
SAPPSGSVRLPVNGANAIIGSNNSVQNVSTPQTFGGKHLVHILPRPSSLS-TSNSTQTFS
VTMSNQQQPQTISLNGQLFALQPVMSSSGTTNQTPMQIIQPTTSEDPNTNVALNTFGALA
SLNQSISQMAGQSCVQLSISQPANPQTATNSQTTPANCVSLTTTIAPSTTTDNSATLPNT
YNFVTTSSVNTVACLPPTMKSKRLNKKPGAKKHLAA-SKPACILNPVK-VGKLDCPRTEG
SAESPCN-DGLLESLPIVLP-SVAVSEAN--------NV------SVSASHSLDILNSES
-------------VMPESVSKSKSAE--VSPCQESVTSEHSAAAPEKSKDSMPILQQETS
QDKPPTSLALSDATKSCTSANVLIPSPSDPQVLASQVSGLSSTTSTASTDYVSEVEIVAE
PCRVDQDS-SDTIQATGLLKGQGLTTLLSDLAKEKDPQ--KSSLSVQIDHPDFSSENSK-
VVNSSVDLHP-KQELLLMNSEDRNPPQQHSCLPDQE-VMNGSLL-TRQADSPMSTSSGSS
RSFSVASMLPETTREDVTSS-T-TNTCDSCTFVEQTDIVALAARAIFDQENIEKERVGIQ
--ADIREVTSKSSEASSLE--GDQPFKSH-PKENGTRQAETTPNEFNSQDSI---EITVD
--RPLEKPSCSLG-IKTSNASLQASTSQPPTLTSLS-------SSITHPLVSCAGLSQTS
DQTAVPTTVNLTVSSSSYGSQPPG-PSLMTEYSQEQLNTMAST-IPNSQIQEPL-LKPNH
ENRKDSAKRAVQDDLLLSSAKRQKHCQPVPLRLENMSLMSRTPDNISDQAQMMVSQIPPN
SSNSVVP--VSNPAHGDGLTRLFPAGNNFVAPALRQTEVQRSSQPSV-AEQ--QQTPASQ
HLQALQQH--VPPQGVSHLHSNHLYIKQQQQQ-----------------QQAGQLRERHH
LYQL-QHHVPHGENAVHSQPHNVHQQRTLQQEVQMQKKRNLVQGTQGSQLSLQPKHHATD
QSRPKSGQPHPHHQQMQQQMQQHFGSSQPEKSCENPSASRNHH-SHPQNHLNQDIMHQQ-
QDVG------RVTSEHVSGHNPMQRLLTSRGLEQ-QMVSQPSIVTRSSDMTCAPHRTERN
RVSSYSAEALIGKTSSNSEQRMGILIQGSRVSDQLEMRSYLDVPRNKSLAIHNMQSHV--
DHTVASD-IRLSDCQTFKPSGASQQPQSNFEVQSSRNNEIGNS-VSSLRSMQSQAFRISQ
N-GPPAIDRQKRLPYPPVQGIPAGNAIPP-RDSENTCHQSFMQSLLAPHLGDQVIGSQRS
LSEHQRNTQCGPSSAIEYNCPPTHESVHIRRDSESQNRESCDMSLGAINTRNSTLNIPFS
SSSSSGDIQGRNTSPNVSVQKSNPMRITDSHGTKGHMNPPVTTNMHGVARPALPHPSVSH
GNADQGP-PVRQANTSVSQRSRHPLQDS-GSSKIRQPERNRSGNQRHSNVFDPSLPHLPL
STSGSMILGRQQPATEKRGSIVRFMPDSPQVPNDNSGPDQHSLSQNFGFPFIPEGGMNPP
INANTSFIPQVTQPSATRAPALIPVDPQNTLPSFYPPYSPAHPTLSNDISIPYFSNQMFS
NPTTEKVNSGSLNNRFGSILSPPRPVGFAQPSFPLLPDMPPMHMTN-SHLSNFNMTSLFP
EIATAL-PDGSAMSPLLTIANSSASDSSKQSSNRPAHNISHILGHDCSSAV

------------------------------------HRKKNRETHNAVERHRKKKINAGI
NRIGELIPCSPALKQSKNMILDQAFKYITEMKRQNDELLLNGGNNEQAEEIKKLRKQLDE
LQKENGRYIELLKANDICLYDDPTIHWKGNLKNAKVSVV---------------------
IPSDQVQKNIIVYSNGTQPNGNNQGASVQGITFNVGHNLQKQTANVVPVQRTCNLVTPVT
IAGIYPTENKPWSQPTVSPLASAQTA--------PVGNVLELSAPENERGVPTTAPASSQ
STPRPATEQELQCSSNNVPQNEQNP---PKSKSDEEGTKATKKTLPQGTSLPSSASVEAS
QGQQVNA---TC-SNTHNSRSDLQESCAVS----TTDTTCVPSVRLSTEAS--CSSANVP
KSTDVVSSAGTPVTSAA-EGVKAVTAISTLAASPLENCWSFSG---SSGVGTSDLKNMSS
LTRMPSAGNTQTTWTTLQLAGNTVQPLSQTPSGIMTALLNEPVNAAGTVSSAHSRPLTTS
I--SLHASVPGDGQAAEQIVVTLPSCPPVPIQPLISQPQVKAQAAGSILPLNSAMQVIQM
AQPVASAVTGAPANQNVIILQPPNPAPCPPIVRAEVPSQNVSQQIVIIQAA-NQNPLPLL
SAQPSASVRLPVNGPTAVANSSGTMQNASLPQTFGGKHLVHILPRPSSLP-SSSSTQTFS
VTMSNQQHPQTISL----------------------------------------------
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----------------------MPEMTENETPTKKQHRKKNRETHNAVERHRKKKINAGI
NRIGELIPCSPALKQSKNMILDQAFKYITEMKRQNDELLLNGGNNEQAEEIKKLRKQLDE
LQKENGRYIELLKANDICLYDDPTIHWKGNLKNAKVSVV---------------------
IPSDQVQKNIIVYSNGTQPNGNNQGASVQGITFNVGHNLQKQTANVVPVQRTCNLVTPVT
IAGIYPTENKPWSQPTVSPLASAQTA--------PVGNVLELSAPENERGVPTTAPASSQ
STPQPATEQELQCSSNNVPQNEQNP---PKSKSDEESTKATKKTLPQGSSLPSSASVEAS
QGQQVNA---TC-SNTYNSRSDLQESCAVS----TTDTTCVPSVRLSTEAS--CSSANVP
KSTDVVSSAGMPVTSAA-EGVKAVIAISTLAASPLENCWSFSG---SSGVGTSDLKNMSS
LTRMPSAGNTQTTWTTLQLAGNTVQPLSQTPSGIMTALLNEPVNAAGTVSSAHSRPLTTS
I--SLHASVPGDGQAAEQIVVTLPSCPPVPIQPLISQPQVKAQAAGSILPLNSAMQVIQM
AQPVASAVTGAPANQNVIILQPPNPAPCPPIVRAEVPSQNVSQQIVIIQAA-NQNP-PLL
SAQPSASVRLPVNGPTAVANSSGTMQNASLPQTFGGKHLVHILPRPSSLP-SSSSTQTFS
VTMSNQQHPQTISLNGQLFALQPVMSSSGASNQAPMQIIQPTTSEDPNTNVALNTFGALA
NLNQSISQMAGQSCLHLSLSHPTNPATV-NNQIATVNCVSLPTSVASSVSAEVSVL-TSA
SNSINASPQKAAAGLTSSAKSKRTNKKTSTKKHQTVNNKVSCPAVPCKDAGKVDCAPVET
VAKSSSS-KGPPENAPAASQ-AVTTPQAG--------STAASSGVSISDSPSKETASSEQ
A------------VKAPSA-----------PEPSSVVSEQLLLTAPPAKDAAPCQQAQAS
QSHPPTASVPSESPKPCKPPNTLTSSGKEAQVTHLQVANGTSAAQGNTTGHTSKAGMISE
PCNIAQDS-PVVMQDADLLEGQGLTKMLSDLTKERTAVEKNSSFTVQGEHSNFPMENSK-
SAES-NDLPE-KQELLLMNTESDTLSQPHSCISDQE-VVSASLITSRQADSPMSTSSGSS
RGFSVASMLPDTTREDVTSSTS-TSTCNSCTFSEQTDIVALAARAIFDQESLEKGGGGIQ
--VNTRDIISKSEVAPLER--EQQPFKPQSVKENNTGPLEAAPNKFSAHETV---QTNVD
--RQVEKPSCSVGGVETSNTPLQISTSQTPSITSLSVNNLIHQSRIVHPLVSCSGLSQSS
EPASIPATVSLSLPSSTYINPSPG-PALMSEYAQEQLNAIRASTMQAPQLQESHLKQQNH
EGRKDSAKRAVQDDLLLSTAKRQKQCQTAPIRLEGMALMNRTPEGIADQTQMLVSQIPPN
SSNSVAP--VSNQGHTDGLNRLFPPNSNFVTPALRQTEVQCGSQPPLS--E--QPGQAGQ
HLQPIQH---VPAQGISHLHSNHPYLKQ---------------------QQAGQLRERHH
LYQL-QHHVTHGENSVHPQPHSVHQQRTIQQEVQMQKKRNLIQGTQATQLSLQQKHHGSD
QTRQKGGQPHPHHQQMQQQMQQHFGASQPEKNCENPATSRNHH-SHPQSHINQDIMHQQQ
QDVGSRQQG--STSEHVSGHNQMQRLMTSRGLEQ-QMVSQASIVSRPSDMTCTPHRQERN
RVSSYSAEALIGKTPSNSEQRIGISLQGPRVSDQLEMRSYLDVSRSKGLAIHNMQGRLSV
DHTVGSDVQRLSDCQTFKPSGPNQQPTGNFDVQASRNSEIGNS-VSSLRGMQSQAFRIGQ
NAA-PSIERQKRLPYQPVQGIPTGNTLPS-RENENTCHQSFMQSLLAPHLGDQVSGSQRS
IPEHQRNTQCGASSTIEYNCPPARESVHIRRDGDGQSRESCDMSIGAINTRNSSLTIPFS
SSSSSGDIQGRNTSPNISVQKSNPMRMTDSHGTKNHMNTPVSSNMHGVVRPTHPHPAVSH
GNGEQGQPSVRQPNSSVTQRSRHPLQDQ--GSKIRQPER-RSGNQRHGNVFDPSLPHLPL
STSGSMILGRQQSTIEKRGSIVRFMSDGPQVSNDNAAPDQHTLSQNFGFPFIPEGGMNPP
INANASFIPPVTQPSATRTPALIPVDPQNTLPSFYPPYSPAHPTLSNDISIPYFPNQMFP
NPSTEKPSSGGLNNRFGSILSPPRPVGFAQPSFPLLPDMPPMHMTNTSHLSNFNLTSLFP
EIATALPPDGSAMSPLLSIANTSASDSSKQPSNRPAHNISHILGHDCSSAV

----------------------MPEMTENETPTKKQHRKKDRETHNAVERHRKKKINAGI
NRIGELIPCSPALKQSKNMILDQALKYITELKRQNDELLLNGGNNEQAEEIKKLRKQLEE
IQKENGRYIELLKANDICLYDDPTIHWKGNLKNSKVSVV---------------------
IPSDQVQKNIIVYSNGSQPGGNSQGTAVQGITFNVGHNLQKQTANVVPVQRTCNLVTPVS
ISGVYPSENKPWHQTTVSALAANQPVPLCLPATISAQNILELSTSESEPSVLVASSGSL-
-IAVPVGPEPPQHRSLLTCLNDQNS---SENKSGQESPKVLKKMVPCATSISSTCSAAAT
KGHHGSK---SC-LSIQDCRSEFQTIFVVS----VTTTVCSQPPRSAGDSR----PANTG
KGADVTSVTAVVVPSAP-GGGKTTTAVSTLSANPMDNGWTLSCSLPSSAVSASDLKNINS
LTRISSAGNTQTTWTTLQLAGNTIQPLSQTPSSAVTPVLNESG--TSPTTTNHSRHMATG
I--NLNNSCPADGQPVEQVVVTLPSYPSLPMQPLIAQPQVKSQPPKNILPLNSAMQVIQM
AQPVGSTVNAAPANQNVIILQPPSTTPCPAVMRAEVPNQTVGQQIVIIQAA-NQNPLPLL
SAPPPGSVRLPVNGATAIIGSNSSVQNVSTPQTFGGKHLVHILPRSSSLS-TSNSTPTFS
VTMSNQQQPQTISLNGQFFALQPVMSSSGTTSQAPMQIIQPTTSEDPNTNVALNTFGALA
SLNQSISQMAGQSCVQLPVSQPGNPQTAANSQTTPASCVSLTTTVAPPLTTDSLVTQPST
YNLVTTPSMNTVACLP-NGRSKRLNKKPGVKKHSAA-NKSACPLNAVGDAGKLDCPSTEG
PAEPSCH-DGLLDGLPVVLP-SVTVSQVD--------S------VSVSGSHSLDILNSES
-------------VMPESVPKSRSAEESGLPSQDSVTSEHFTMAPAKSKDSLPVLQRETS
QDKPPTSLALPDATKSCTSANVLISSAKDPHILVSQVSDLSSTTSTASTGCVSEVEIIAE
PCRVEQDS-SDTVPATGLLKGQGLTALLSGLAKEKDPQ--KSSLSVQVDHPDFASENSK-
IVDSSVDLHP-KQELLLMSSDDRDPGPHPPCIPDQE-VVNGSLLTSRQADSPMSTSSGSS
RSFSVASMLPETTREDVASSAT-TNTCDGCTFVEQTDIVALAARAIFEQENLEKGRAGTQ
--ADIREVTSKPSEASSIE--GDQTFKTQTSKENGPGRTEATANEFNSQDSI---EATVD
--RPLEKPSCSVG-IKTSNTSLQVSASQPPSITSLSVNNLIHQSSISHPLVSCTGLSQTS
EQTAVPVTVNLTVSSSSYGSQPPG-PSLMTEYSQEQLNTLAGT-ISNPQIPEPL-LKPSH
ESRKDSAKRAVQDDLLLSSAKRQKHCQPAPLRLEGLSLMSRTPDSISDQTQMMVGQIPPN
SSNPVVSVSLSNPAHGDGLTRLFPPSNNFVAPALRQTEVQCSSQPSV-AEQ--QQTQANQ
HLQALQQH--VPAQGVPHLHSNHLYLKQQQQQQQQQQQQQQQQQQQQQQQQAGQLRERHH
LYQL-QHHVPHAESSVHSQPHNVHQQRTLQQEVQMQKKRNLVQGTQASQLSLQPKHHGTD
QARPKSSQPHPHHQQMQQQMQQHFGSSQPEKSCENPSTSRNHH-NHPQNHLNQDIMHPQ-
QDVGSRQQGSGVSSEHVSGHNPMQRLLTSRGIEQ-QMVSQPSIVTRPSDMTCTPHRPERN
RVSSYSAEALIGKTSSNSEQRMGISIQGSRVSDQLEMRSYLDVPRNKSLAIHNMQGRV--
DHSVASD-IRLSDCQTFKPSGASQQPQSNFEVQSSRNNEIGNP-VSSLRGMQSQAFRIGQ
NPGPPPIDRQKRLPYPPVQSIPTGNALPP-RDSENTCHQSFMQSLLAPHVGDQVIGSQRS
LSEHQRNTQCGPSSAIEYNCPPAHESVHIRRESESQNRESCDMSLGAINTRNSTLTIPFS
SSSSSGDIQGRNTSPNVSVQKSNSMRITDSHGTKGHMNPPVTTNMHGVARPALPHPSVSH
GNADQGP-PVRQTNSSVPQRSRHPLQDS-SGSKIRQPERTRSGNQRHSNVFDPSLPHLPL
ATSGSMILGRQQPPAEKRGSIVRFMPESPQVPNDNAAPDQHTLSQNFGFPFIPEGGMNPP
INANTSFIPQVTQPSATRTPALIPVDPQNTLPSFYPPYSPAHPTLSNDISIPYFSNQMFS
NPSTEKVNSGSLNNRFGSILSPPRPVGFAQPSFPLLPDMPPMHMTN-SHLSNFNMTSLFP
EIATAL-PDGSAMSPLLTIANSSASDSSKQSSNRPAHNISHILGHDCSSAV

----------------------MPEMTENETPTKKQHRKKNRETHNAVERHRKKKINAGI
NRIGELIPCSPALKQSKNMILDQAFKYITELKRQNDELLLNGGNNEQAEEIKKLRKQLEE
IQKENGRYIELLKANDICLYDDPTIHWKGNLKNSKVSVV---------------------
IPSDQVQKNIIVYSNGNQPGGNSQGTAVQGITFNVSHNLQKQTANVVPVQRTCNLVTPVS
ISGVYPSENKPWHQTTVPALATNQPVPLCLPAAISAQSILELPTSESESNVLGATSGSL-
-IAVSIESEPHQHHSLHTCLNDQNS---SENKNGQENPKVLKKMTPCVTNIPHSSSATAT
KVHHGNK---SC-MSIQDFRGDFQNTFVVS----VTTTVCSQPPRTAGDSS----PMSIS
KSADLTSTATVVASSAP-GVGKATIPISTLSGNPLDNGWTLSCSLPSSSVSTSDLKNINS
LTRISSAGNTQTTWTTLQLAGNTIQPLSQTPSSAVTPVLNESG--TSPTTSNHSRHVATD
I--NLNNSFPADGQPVEQVVVTLPSCPSLPMQPLIAQPQVKSQPPKNILPLNSAMQVIQM
AQPVGSAVNAAPTNQNVIILQPPSTTPCPTVMRAEVPNQTVGQQIVIIQAA-NQNPLPLL
PAPPPGSVRLPINGANTVIGSNNSVQNVPTPQTFGGKHLVHILPRPSSLS-ASNSTQTFS
VTMSN-QQPQTISLNGQLFALQPVMSSSGTTNQTPMQIIQPTTSEDPNTNVALNTFGALA
SLNQSISQMAGQSCVQLSISQPANSQTAANSQTTTANCVSLTTTAAPPVTTDSSATLAST
YNLVSTSSMNTVACLP-NMKPKRLNKKPGGRKHLAA-NKSACPLNSVRDVSKLDCPNTEG
SAEPPCN-DGLLESFPAVLP-SVSVSQAN---------SVSVSAS-----HSLGVLSSES
-------------LIPESVSKSKSAEKSSPPSQESVTSEHFAMVAAKSKDSTPNLQQETS
QDKPPSSLALSDAAKPCASANVLIPSPSDPHILVSQVPGLSSTTSTTSTDCVSEVEIIAE
PCRVEQDS-SDTMQTTGLLKGQGLTTLLSDLAKKKNPQ--KSSLSHQMDHPDFSSENPK-
IVDSSVNLHP-KQELLLMNNDDRDPPQHHSCLPDQE-VINGSLITGRQADSPMSTSSGSS
RSFSVASMLPETTREDVTSNAT-TNTCDSCTFVEQTDIVALAARAIFDQENLEKGRVGLQ
--ADIREVASKPSEASLLE--GDPPFKSQIPKESGTGQAEATPNEFNSQGSI---EATME
--RPLEKPSCSLG-IKTSNASLQDSTSQPPSITSLSVNNLIHQSSISHPLASCAGLSPTS
EQTTVPATVNLTVSSSSYGSQPPG-PSLMTEYSQEQLNTMTST-IPNSQIQEPL-LKPSH
ESRKDSAKRAVQDDLLLSSAKRQKHCQPAPLRLESMSLMSRTPDTISDQTQMMVSQIPPN
SSNSVVP--VSNPAHGDGLTRLFPPSNNFVTPALRQTEVQCGSQPSV-AEQ--QQTQASQ
HLQALQQH--VPAQGVSHLHSNHLYIKQQQQQQ------------QQQQQQAGQLRERHH
LYQM-QHHVPHAESSVHSQPHNVHQQRTLQQEVQMQKKRNLVQGTQTSQLSLQPKHHGTD
QSRSKSGQPHPHHQQMQQQMQQHFGSSQTEKSCENPSTSRNHH-NHPQNHLSQDIMHQQ-
QDVGSRQQGSGVSSEHVSGHNPMQRLLTSRGLEQ-QMVSQPSIVTRSSDMTCTPHRPERN
RVSSYSAEALIGKTSSNSEQRMGISIQGSRVSDQLEMRSYLDVPRNKSLAIHNMQGRV--
DHTVASD-IRLSDCQTFKPSGASQQPQSNFEVQSSRNNEIGNP-VSSLRSMQSQAFRISQ
NTGPPPIDRQKRLPYPPVQSIPTGNGIPS-RDSENTCHQSFMQSLLAPHLSDQVIGSQRS
LSEHQRNTQCGPSSAIEYNCPPTHENVHIRRESESQNRESCDMSLGAINTRNSTLNIPFS
SSSSSGDIQGRNTSPNVSVQKSNPMRITESHATKGHMNPPVTTNMHGVARPALPHPSVSH
GNGDQGP-AVRQANSSVPQRSRHPLQDS-SGSKIRQPERNRSGNQRQSTVFDPSLPHLPL
STGGSMILGRQQPATEKRGSIVRFMPDSPQVPNDNSGPDQHTLSQNFGFSFIPEGGMNPP
INANASFIPQVTQPSATRTPALIPVDPQNTLPSFYPPYSPAHPTLSNDISIPYFPNQMFS
NPSTEKVNSGSLNNRFGSILSPPRPVGFAQPSFPLLPDMPPMHMTN-SHLSNFNMTSLFP
EIATAL-PDGSAMSPLLTIANSSASDSSKQSSNRPAHNISHILGHDCSSAV

----------------------MPEMTEHETPTKKQHRKKNRETHNAVERHRKKKINAGI
NRIGELIPCSPALKQSKNMILDQAFKYITELKRQNDELLLNGGNNEQGKENLRLIFF--I
IFKCVGLV----------------------------------------------------
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----------------------MPEMTENETPTKKQHRKKNRETHNAVERHRKKKINAGI
NRIGELIPCSPALKQSKNMILDQAFKYITELKRQNDELLLNGGNNEQAEEIKKLRKQLEE
IQKENGRYIELLKANDICLYDDPTIHWKGNLKNSKVSVV---------------------
IPSDQVQKNIIVYSNGSQPGGNSQGTAVQGITFNVGHNLQKQTANVVPVQRTCNLVTPVS
ISGVYPSENKPWHQTTVSALAANQPVPLCLPATISAQNILELSTSESESSVLGATSASL-
-IAVPIGPEPPQRRSLHTCLNDQSS---PENKNGQESPKLVKKTVSCATSIPTASSATAT
KVHHGSK---SC-LSVQDFRNDFQTTFVVS----VTTTVCSQPPRSAGDSC----PASIS
KGADSASVTAVVAPSAP-GGGKTTTPISTVSANPLDNGWTLSCSLPSSSVSASDLKNINS
LTRISSAGNTQTTWTTLQLAGNTIQPLSQTPSSAVTPVLNESG--TSPTTTNHSRHVATG
V--NLNNSFPADGQAVEQVVVTLPSCPSLPMQPLIAQPQVKSQPPKNILPLNSAMQVFQM
AQPVGSAVNAAPANQNVIILQPPSTTPCPTVMRAEVPNQTVGQQIVIIQAA-NQNPLPLL
SAPPPGSVRLPVNGTSALIGSNNSVQNVSNPQTFGGKHLVHILPRPSSLS-TSSSTQTFS
VTMSNQQQPQTISLNGQLFALQPVMSSSGTTNQTPMQIIQPTTSEDPNTNVALNTFGALA
SLNQSISQMAGQSCVQLSISQPANPPTAANSQTTPVNCVSLTTTVASPMTTDNSATLPST
YSLVTTPSVNTVACLP-NVRSKRLNKKPSAKKHLGA-NKSACPLNPVRDASKLDCPSAEA
TAEPSCA-DGLLESLPVVLP-SVTVSQAN---------SISVSGS-----HSLDVLNSES
-------------VIPESVPKSKSAEETSSPSQEPVTSEHFVTAPAKSKDSAPILQRETS
QDKPPTSLALSDAAKSCTSANVLIPSPSDPHILVSQVSGLSSTTS-TSTDCVSEVEIIAE
PCRVEQDSTSETMQTTALLKGQGLTALLSGLAKEKDPQ--KLSLSVQVDHPDFSSDSSK-
IVDSSVELHP-KQDLLLMNSDDRDPGQHHSCIPDQE-VINGSLLGSRQADSPMSTSSGSS
RSFSVASMLPETTREDVTSNTT-TNTCDSCTFVEQTDIVALAARAIFDQENLEKGRAGSQ
--ADMREVASKPSEASPLE--GDQPFKTQISKEGGTGQTEATPNEFNSQDSI---EATVD
--RPLGKPSCSVG-IKTSNASLQVSTSQPPSITSLSVNNLIHQSSISHPLVTCAGLSQTS
EQTAVPATVNLTVASSSYTSQPPG-PALMTEYPQEQLNTIAGT-IPNPQIQEPL-LKPSQ
ESRKDSAKRAVQDDLLLSSAKRQKHCQPAPLRLEAMSLMSRTPDSISDQAQMMVNQLPPN
SANSVGP--ISNPAHGDGLTRLFPPSNNFVASALRQTEVQCSSQNSV-AEQ--QQTQASQ
HLQALQQH--VPAQGVSHLHSNHLYLKQQQQ----------------QQQQAGQLRERHH
LYQL-QHHVPHAESSVHSQPHNVHQQRTLQQEVQMQKKRNLVQGSQASQLSLQPKHHGTD
QSRPKSGQPHPHHQQMQQQMQQHFGSTQPEKSCENPSTSRNHH-NHPQNHLNQDIMHQQ-
QDVGSRQQGSGVSSEHVSGHNPMQRLLTSRGLEQ-QMGSQPSIVTRPSDMTCTPHRPERN
RVSSYSAEALIGKTSSNSEQRMGISIQGSRVSDQLEMRSYLDVPRNKSLAIHNMQGRV--
DHTVASD-IRLSDCQTFKPSGASQQPQSNFEVQSSRNNEIGNP-VSSLRSMQSQAFRISQ
NPGPPPIDRQKRLPYPAVQSIPTGNAIPP-RDSENPCHQSFMQSLLAPHLGDQVLGSQRS
LSEHQRNTQCGPSSAIEYTCPPTHESVHIRRESESQNRESCDMSLGAINTRNSTLNIPFS
SSSSSGDIQGRNTSPNVSVQKSNPMRITDSHGTKGHMNPPVTTNMHGVARPALPHPSVSH
GNAEQGP-PVRPTNSSVPQRSRHPLQDS-SGSKIRQPERNRSGNQRHSNVFDPSLPHLPL
STSGSMILGRQQPTTEKRGSIVRFMPDSPQVPNDNSAPDQHTLSQNFGFPFIPEGGMNPP
INANTSFIPQVTQPSATRTPALIPVDPQNTLPSFYPPYSPAHPTLSNDISIPYFSNQMFS
NPSTEKVNSGGLNNRFGSILSPPRPVGFAQPSFPLLPDMPPMHMTN-SHLSNFNMTSLFP
EIATAL-PDGSAMSPLLTIANSSASDSSKQSSNRPAHNISHILGHDCSSAV

----------------------MPEMTENETPTKKQHRKKNRETHNAVERHRKKKINAGI
NRIGELIPCSPALKQSKNMILDQAFKYITELKRQNDELLLNGGNNEQAEEIKKLRKQLEE
IQKENGRYIELLKANDICLYDDPTIHWKGNLKNSKVSVV---------------------
IPSDQVQKNIIVYSNGSQPGGNSQGTAVQGITFNVGHNLQKQTANVVPVQRTCNLVTPVS
ISGVYPSENKPWHQTTVSALATNQPVPLCLPATISAQNILELSTSESDSSVLGATSGSL-
-IAVPVGPEPHQHHSLHTYPNDQNP---LENKNGQESPKLLKKTVPCATSIPPTSSATAT
KVHHGNK---SC-LSIQDLRGDFQNTFVVS----VTTTVCSQPPRSAGGSS----PVSNS
KSADLTSTATVVAPSVS-GVGKATTPVSTLSANSVDNGWTLSCSLPSSSVSASDLKNINS
LTRISSAGNTQTTWTTLQLAGNTIQPLSQTPSSTMTPALNESG--TSPTTSNHSRHVATG
I--NLNTSFLADGQSVEQVVVTLPSCPSLPMQSLIAQPQVKSQPPKNILPLNSAMQVIQM
AQPVGSAVNATPANQNVIILQPPSTTPCPTVVRAEVPNQTVGQQIVIIQAA-NQNPLPLL
SAPPPGSVRLPINGANTIIGSNNSVQNVSTPQTFGGKHLVHILPRPSSLS-TSSSTQTFS
VTMSNQQQPQTISLNGQLFALQPVMSSSGTTNQTPMQIIQPTTSEDPNTNVALNTFGALA
SLNQSISQMAGQSCVQLSISQPANPQTAANSQTTPANCVSLATTVAPPVTTDHSATLPST
YNLVTPPSMNTLACLPPNVKSKRLTKKPGAKKHLAA-NKSACPPNSVRDVSKLDCPSIEG
PVEPPCN--GLLEGLPAELP-SVPVSQAN---------SVSV--S-----HSLDILNSES
-------------VIPESVSKSKTVEESSSPSQESVTSEHFAVAPAKPKDSTPSLQQETS
QDKSPTSLALSSAAKSCTSANVLIPSPNDAHILVSQVPGLSSTTSTTGTDCVSEVEIIAE
PCRVEQDS-SDTMQNTGLLKGQGLTTLLSDLAKEKDPQ--KSSLSDQMDHPDFSAENSQ-
ITESSVNLHP-KQEILLMSNDDRDPPQHHSCLPDQE-VINGSLVTSRQADSPMSTSSGSS
RSFSVASMLPETTREDVTGNAA-TNTCDSCSFVEQTDIVALAARAIFDQENLEKGKVGLQ
--ADMREVTSKPSEASSLE--RDPPFKSQIPKENGTGQAEATPSEFNSQDSI---ETAVE
RGKPREKPCCSLG-IKTSNASLQASTSQPPSITSLSVNNLIHQSSISHPLVSCAGLSQTS
EQTTVPATVNLTVSSGSYGSQPPG-PSLMTEYSQEQINTMTST-IPNSQIQEPL-LKPSH
ESRKDSAKRAVQEDLLLSSAKRQKHCQPAPLRLESMSLMSRTPDGISDQAQMMVSQIPPN
SSNSVVP--VSNPAHGDGLTRLFPPSNNFVAPSLRQTEVQCNSQPPV-AEQ--QQTQANQ
HLQALQQH--VPAQGVSHLHSNHLYIKQQQ-------------------QQAGQLRERHH
LYQL-QHHVPHPESSVHSQPHNVHQQRTLQQEVQMQKKRNLVQGTQASQLSLQPKHHGTD
QSRPKNGQPHPHHQQMQQQMQQHFGSSQPEKNCENPSTSRNHH-NHPQNHLNQDIMHQQ-
QDVGSRQQGSGVSSEHVSGHNPMQRLLTSRGLEQ-QMVSQPSIVTRASDMTCTPHRPERN
RVSSYSAEALIGKTSSNSEQRMGISIQGSRVSDQLEMRSYLDVSRNKSLAIHNMQGRV--
DHAVASD-IRLSDCQTFKASGASQQPPSNFEVQSSRNNEIGNP-VSSLRSMQSQAFRISQ
NTGPPPIDRQKRLPYTPVQSIPAGNAIPP-RDSENTCHQSFMQSLLAPHLGDQVIGNQRS
LSEHQRNTQCGPSSAIEYNCPSTHESVHIRRENESQNRESCDMSLGAINTRNSTLNIPFS
SSSSSGDIQGRNTSPNVSVQKSNPMRITDSHGTKGHMNPPVTTNMHGVARPALPHPSVSH
GNADQGP-PVRQATSSVPQRSRHLLQDS-SGSKIRQPERNRSGNQRHSNVFDPSLPHLPL
STSGSMILGRQQPATEKRGSIVRFMPDSPQVPNDNSGPDQHTLSQNFGFSFIPEGGMNPP
INANTSFIPQVTQPSATRTPALIPVDPQNTLPSFYPPYSPAHPTLSNDISIPYFSNQMFS
NPSTEKVNSGSLNNRFGSILSPPRPVGFAQPSFPLLPDMPPMHMTN-SHLSNFNMTSLFP
EIATAL-PDGSAMSPLLTIANSSSSDSSKQSSNRPAHNISHILGHDCSSAV

----------------------MPEMTENETPTKKQHRKKNRETHNAVERHRKKKINAGI
NRIGELIPCSPALKQSKNMILDQAFKYITELKRQNDELLLNGGNNEQAEEIKKLRKQLEE
IQKENGRYIELLKANDICLYDDPTIHWKGNLKNSKVSVV---------------------
IPSDQVQKNIIVYSNGNQPGGNSQGTAVQGITFNVSHNLQKQTANVVPVQRTCNLVTPIS
ISGVYPSENKPWHQTTVPALATNQPVPLCLPAAISAQSILELPTSESESGVLGASSGSL-
-IAVSVGPEPHQHHSLHTCLNDQNS---SENKNGQENPKLLKKMTPCAINIPLSSSATAT
KVHHGNK---SC-LSIQDFRGDFQNTFVVS----VTTTVCSQPPRTADDSS----PVSIS
KSADLTSTATVVASSAP-GVGKATIPISTLSGNPLDNGWTLSCSLPSSSVSTSDLKNINS
LTRISSAGNTQTTWTTLQLAGNTIQPLSQTPSSAVTPVLNESG--TSPTTSNHSRHVATG
I--NLNNSFPADGQPVEQVVVTLPSCPSLPMQPLIAQPQVKSQPPKNILPLNSAMQVIQM
AQP---AVNAAPTNQNVIILQPPSTTPCPTVMRAEVPNHTVGQQIVIIQAA-NQNPLPLL
SAPPPGSVRLPINGANTVIGSNNSVQNVSTPQTFGGKHLVHILPRPSSLS-VSNSTQTFS
VTMSN-QQPQTISLNGQLFALQPVMSSSGTTNQTPMQIIQPTTSEDPNTNVALNTFGALA
SLNQSISQMAGQSCVQLSISQPANAQTAANSQTTTANCVSLAT-AAPPVTTDSSATLAST
YNLVSTSSMNTVACLPPNMKSKRLNKKPGARKHLAA-NKSACPLNPVRDVSKLDCPNTES
SAELPYN-DGLLESFPAVLP-PVSMSQAN---------SVSVSAS-----HSLGALNSGS
-------------LIPESVSKSKSTEKSSSPSQESVTSEHFAMAPAKSKDSTPNLQQETP
QDKPPSHLALSDAAKPCTSANVLIPSPSDPHILVSQVSGLSSTTSTTSTDCVSEVEIIAE
PCRVEQDS-SDTMQTTGLLKGQGLTTLLSDLAKKKNPQ--KSSLSDQMDHPDFSSENPK-
IVDSSVNLHP-KQELLLMNSDDRDPPQHHSCLPDQE-VINGSLITSRQADSPMSTSSGSS
RSFSVASMLPETTREDVTSNAT-ANTCDSCTFVEQTDIVALAARAIFDQENLEKGRVGLQ
--ADIREVASKPSEASSLE--GDPPFKSQIPKENGTGQAEATPNEFNSQDSI---EATME
--RPLEKPSCSLG-IKTSNAPLQASPSQPPSITSLSVNNLIHQSSISHPLASCAGLSPTS
EQTTVPATVNLTVSSSSYDSQPPG-PSLMTEYSQEQLNTMTST-IPNSQIQEPL-LKPSH
ESRKDSAKRAVQDDLLLSSAKRQKHCQPTPLRLESMSLMSRTPDTISDQTQMLVSQIPPN
SSNSVVP--VSNPAHGDGLTRLFPPSNNFVAPALRQTEVQCGSQPSV-AEQ--QQTQASQ
HLQALQQH--VPAQGVSHLHSNHLYIKQQQQQQQ----------QQQQQQQAGQLRERHH
LYQM-QHHVPHAESSVHSQPHNVHQQRTLQQEVQMQKKRNLVQGTQASQLSLQPKHHGTD
QSRSKSGQPHPHHQQMQQQMQQHFGSSQTEKSCENPSTSRNHH-NHPQNHLNQDIMHQQ-
QDVGSRQQGSGVSSEHVSGHNPMQRLLTSRGLEQ-QMVSQPSIVTRSSDMTCTPHRPERN
RVSSYSAEALIGKTSSNSEQRMGISIQGSRVSDQLEMRSYLDVPRNKSLAIHNMQGRV--
DHTVASD-IRLSDCQTFKPSGASQQPQSNFEVQSSRNNEIGNP-VSSLRSMQSQAFRISQ
NTGPPPIDRQKRLPYPPVQSIPTGNGIPS-RDSENTCHQSFMQSLLAPHLSDQVIGSQRS
LSEHQRNTQCGPSSAIEYNCPPTHENVHIRRESDSQNRESCDMSLGAINTRNSTLNIPFS
SSSSSGDIQGRNTSPNVSVQKSNPMRITDSHATKGHMNPPVTTNMHGVARPALPHPSVSH
GNGDQGP-PVRQANSSVPQRSRHPLQDS-SGSKIRQPERNRSGNQRQSNVFDPSLPHLPL
STGGSMILGRQQPATEKRGSIVRFMPDSPQVPNDNSGPDQHTLSQNFGFSFIPEGGMNPP
INANASFIPQVTQPSATRTPALIPVDPQNTLPSFYPPYSPAHPTLSNDISIPYFPNQMFS
NPSTEKVNSGSLNNRFGSILSPPRPVGFAQPSFPLLPDMPPMHMTN-SHLSNFNMTSLFP
EIATAL-PDGSAMSPLLTIANSSASDSSKQSSNRPAHNISHILGHDCSSAV

----------------------MPEMTENETPTKKQHRKKNRETHNAVERHRKKKINAGI
NRIGELIPCSPALKQSKNMILDQAFKYITELKRQNDELLLNGGNNEQAEEIKKLRKQLEE
IQKENGRYIELLKANDICLYDDPTIHWKGNLKNSKVSVV---------------------
IPSDQVQKNIIVYSNGSQPCGNSQGTAVQGITFNVGHNLQKQTANVVPVQRTCNLVTPVS
ISGVYPSENKPWHQTTVSALAANQPVPLCLPATIPAQNILELSTSESESSVLGATNGPL-
-IAVPIGPEPHQHRSVHTCLSDQSS---PENKNGQESPKLLKKTVPCATGVPTTSSATAT
KVHHGSQ---SC-LSIQDFRNDFQTTFVVS----VTTTVCSQPPRSAGDAC----PVSIS
KGADSASVTAAVAPSAP-AGGKTTTPVSTLSANPLDNSWTLSCSLPSSSVSASDLKNINS
LTRISSAGNTQTTWTTLQLAGNTIQPLSQTPSSAVTPVLNESG--SSPPTTSHSRHVATG
V--NVNNSFPADGQVVEQVVVTLPSCPSLPMQPLIAQPQVKSQPPKSILPLNSAMQVIQM
AQPVGSAVNAAAANQNVIILQPPSTTPCPTVMRAEVPNQTVGQQIVIIQAA-NQNPLPLL
SAPPPGSVRLPVSGANALLGSNSSVQNVSTPQTFGGKHLVHILPRPSSLS-TSSSTQTFS
VTMSNQQQPQTISLNGQLFALQPVMSSSGTTNQTPMQIIQPTTSEDPNTNVALNTFGALA
SLNQSISQMAGQSCVQLSISQPANPPTAASSQTIPVHSVSLTTTVASPMTTDNSATLPST
YSLVTTPSVNTVACLP-NVKSKRF-KKPGAKKHLAA-HKSACPPNPVREVGKLACPGTEA
TAEPSCG-DGLLESLPVVLP-SVTISQAN---------CVSVSGS-----HSLDVLNPES
-------------VIPESVPKSKSTEESSSPSQASVTSEHFVMAPAKSKDSAPILQQEAS
QDKPPASLALSDAAKCCTSASVLIPSPNDPHLLVSQVSGLSSTTSTTSTDCASEVEIIAE
PCRVEQDS-SDTMQTTGLLKGQGLTALLSGLAKEKDSQ--KLSLSVPVDHPDFPSENSK-
MADSSVDLHP-KQELLLMNSDDRGPGQHHSCVPDQE-VINGSLLVSRQADSPMSTSSGSS
RSFSVASMLPETTREDVTSNAT-TNTCDSCTFVEQTDIVALAARAIFDQENLEKGRAGTQ
--ADMREVTSKPSEASPLE--GDQPFKTQISKESGPGQAEATPNEFNSQDSI---EATVD
--RSLGKPSCSVG-IKTSNASLQVSTSQPPSITSLSVNNLIHQSTISHPLVSCAGLSQTA
EQAPVPATVNLTVASSSYGGQPPG-PALMTEYSQEQLNTITGT-IPNPQVQEPL-LKPSQ
ESRKDSAKRAVQDDLLLSSAKRQKHCQPAPLRLEAMSLMNRTPDSISDQTQMMVSQLPPN
SANSVVP--ISNPAHGDGLARLFPPSNNFGAPALRQTEVQCSSQNSV-TEQ--QQTQASQ
HLQALQQH--VPAQGVSHLHGNHLYLKQQQQQQQ-----------QQQQQQAGQLRERHH
LYQL-QRHAPHAESSVHSQPHNVHQQRTLQQEVQMQKKRNLVQGTQASQLSLQPKHHGTD
QSRPKSGQPHPHHQQMQQQMQQHFGSSQPEKSCENPSTSRSHH-NHPQNHLSQDMIHQQ-
QDVGSRQQGSGVSSEHVSGHNPLQRLLTSRGIEQ-QMVSQPSIVTRPSDMPCTPHRPERN
RVSSYSAEALIGKTSSNSEQRMGMSLQGSRVSDQLEMRSYLDVPRNKSLAVHNMQGRV--
DHTVASD-IRLTDCQTFKPSGASQQPQSNFEVQSSRNSEIGNP-VSSLRSMQSQAFRISQ
NPGPPPIDRQKRLSYPPVQSIPTGNAIPP-RDSENTCHQSFMQSLLAPHLGDQVLGSQRS
LSEHQRNTQCGPSSAIDYNCPPTHESVHIRRESESQNRESCDMSLGAINTRNSTLNIPFS
SSSSSGDIQGRNTSPNVSVQKSNPMRITDSHGTKGHMNPPVTTNMHGVARPALPHPSVSH
GNAEQGP-PVRPTNSSVPQRSRHPLQDS-SGSKIRQPERNRSGNQRHSNVFDPSLPHLPL
STSGSMILGRQQAATEKRGSIVRFMPDSPQVPNDNSAPDQHTLSQNFGFPFIPEGGMNPP
INANTSFIPQVTQPSATRTPALIPVDPQNTLPSFYPPYSPAHPTLSNDISIPYFSNQMFS
NPSTEKVNSGSLNNRFGSILSPPRPVGFAQPSFPLLPDMPPMHMTN-SHLSNFNMTSLFP
EIATAL-PDGSAMSPLLTIANSSASDSSKQSSNRPAHNISHILGHDCSSAV

----------------------MPEMTEHETPSKKQHRKKNRETHNAVERHRKKKINAGI
NRIGELIPCSPALKQSKNMILDQAFKYITELKRQNDELLLNGGNNEQGEDLDISTS----
----------------CCLLDI----WLFVLQ----------------------------
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----------------------MPEMTENETPTKKQHRKKNRETHNAVERHRKKKINAGI
NRIGELIPCSPALKQSKNMILDQAFKYITELKRQNDELLLNGGNNEQAEEIKKLRKQLEE
IQKENGRYIELLKANDICLYDDPTIHWKGNLKNSKVSVV---------------------
IPSDQVQKNIIVYSNGNQPGGNSQGTAVQGITFNVSHNLQKQTANVVPVQRTCNLVTPIS
ISGVYPSENKPWHQTTVPALATNQPVPLCLPAAISAQSVLELPTSESESSVLGASSGSL-
-IAVSVGPEPHQHHSLHTCLNDQNS---SENKNGQENPKLLKKMTPCAVNIPLSSSATAT
KVHHGNK---SC-LSIQDFRGDFQNTFVVS----VTTTVCSQPPRTADDSS----PMSIS
KSADLTSTATVVASSAP-GVGKATIPISTLSGNPLDNGWTLSCSLPSSSVSTSDLKNINS
LTRISSAGNTQTTWTTLQLAGNTIQPLSQTPSSAVTPVLNESG--TSPTTSNHSRHVATG
I--NLNNSFPADGQPVEQVVVTLPSCPSLPMQPLIAQPQVKSQPPKNILPLNSAMQVIQM
AQPVGSAVNAAPTNQNVIILQPPSTTPCPTVMRAEVPNHTVGQQIVIIQAA-NQNPLPLL
SAPPPGSVRLPINGANTVIGSNNSVQNVSTPQTFGGKHLVHILPRPSSLS-VSNSTQTFS
VTMSN-QQPQTISLNGQLFALQPVMSSSGTTNQTPMQIIQPTTSEDPNTNVALNTFGALA
SLNQSISQMAGQSCVQLSISQPANAQTAANSQTTTANCVSLAT-AAPPVTTDSSATLAST
YNLVSTSSMNTVACLPPNMKSKRLNKKPGARKHLAA-NKSACPLNPVRDVSKLDCPNTES
SAELPCN-DGLLESFPAVLP-PVSMSQAN---------SVSVSAS-----HSLGVLNSES
-------------LIPESVSKSKSIEKSSSPSQESVTSEHFAMAPAKSKDSTPNLQQETP
QDKPPSHLALSDAAKPCTSANVLIPSPSDPHILVSQVSGLSSTTSTTSTDCVSEVEIIAE
PCRVEQDS-SDTMQTTGLLKGQGLTTLLSDLAKKKNPQ--KSSLSDQMDHPDFSSENPK-
IVDSSVNLHP-KQELLLMNSDDRDPPQHHSCLPDQE-VINGSLITSRQADSPMSTSSGSS
RSFSVASMLPETTREDVTSNAT-ANTCDSCTFVEQTDIVALAARAIFDQENLEKGRVGLQ
--ADIREVASKPSEASSLE--GDPPFKSQIPKENGTGQAEATPNEFNSQDSI---EATME
--RPLEKPSCSLG-IKTSNAPLQASPSQPPNITSLSVNNLIHQSSISHPLASCAGLSPTS
EQTTVPATVNLTVSSSSYDSQPPG-PSLMTEYSQEQLNTMTST-IPNSQIQEPL-LKPSH
ESRKDSAKRAVQDDLLLSSAKRQKHCQPAPLRLESMSLMSRTPDTISDQTQMMVSQIPPN
SSNSVVP--VSNPAHGDGLTRLFPPSNNFVAPALRQTEVHCGSQPSV-AEQ--QQTQASQ
HLQALQQH--VPAQGVSHLHSNHLYIKQQQQQQQQQ-------QQQQQQQQAGQLRERHH
LYQM-QHHVPHAESSVHSQPHNVHQQRTLQQEVQMQKKRNLVQGTQASQLSLQPKHHGTD
QSRSKSGQPHPHHQQMQQQMQQHFGSSQTEKSCENPSTSRNHH-NHPQNHLNQDIMHQQ-
QDVGSRQQGSGVSSEHVSGHNPMQRLLTSRGLEQ-QMVSQPSIVTRSSDMTCTPHRPERN
RVSSYSAEALIGKTSSNSEQRMGISIQGSRVSDQLEMRSYLDVPRNKSLAIHNMQGRV--
DHTVASD-IRLSDCQTFKPSGASQQPQSNFEVQSSRNNEIGNP-VSSLRSMQSQAFRISQ
NTGPPPIDRQKRLPYPPVQSIPTGNGIPS-RDSENTCHQSFMQSLLAPHLSDQVIGSQRS
LSEHQRNTQCGPSSAIEYNCPPTHENVHIRRDSDSQNRESCDMSLGAINTRNSTLNIPFS
SSSSSGDIQGRNTSPNVSVQKSNPMRITDSHATKGHMNPPVTTNMHGVARPALPHPSVSH
GNGDQGP-PVRQANSSVPQRSRHPLQDS-SGSKIRQPERNRSGNQRQSNVFDPSLPHLPL
STGGSMILGRQQPATEKRGSIVRFMPDSPQVPNDNSGPDQHTLSQNFGFSFIPEGGMNPP
INANASFIPQVTQPSATRTPALIPVDPQNTLPSFYPPYSPAHPTLSNDISIPYFPNQMFS
NPSTEKVNSGSLNNRFGSILSPPRPVGFAQPSFPLLPDMPPMHMTN-SHLSNFNMTSLFP
EIATAL-PDGSAMSPLLTIANSSASDSSKQSSNRPAHNISHILGHDCSSAV

----------------------------------------MDFPPCLVERHRKKKINAGI
NRIGELIPCSPALKQSKNMILDQAFKYITELKRQNDELLLNGGNNEQAEEIKKLRKQLEE
IQKENGRYIELLKANDICLYDDPTIHWKGNLKNSKVSVV---------------------
IPSDQVQKNIIVYSSGSQPGGNSQGTAVQGITFNVGHNLQKQTANVAPVQRACNLVTPVS
ISGVYPPENKPWHQTTVSALAANQPVPLCLPATISAQNIVELSTSESESSVLGATSGSL-
-IAVPIGPEAHQHRPLHTCLNDRNS---PENKNGQESPKLVRKTVPCATSIPTTSSATAA
KVHHGSK---SC-LSIQDFRNDFQTTFVVS----VTTTVCSQPPRSAGDSC----PVSIS
KGADSAAVTAVVAPSAP-GGGKTATPVSTLSASPLDSSWTLSCSLPSSSVSASDLKNMNS
LTRISSAGNTQTTWTTLQLAGNTIQPLSQTPSSAVTPVVNESG--PSPTTANHGRPVATG
V--NLSNSFPADGQAIEQVVVTLPSCPSLPMQPLIAQPQVKSQPPKNILPLNSAMQVIQM
AQPVGSAVNTAPGNQNVIILQPPSTTPCPAVMRAEVPNQTVGQQIVIIQAA-NQNPLPLL
SAPPPGSVRLPVNGASALIGSNNSVQNVSTPQTFGGKHLVHILPRPSSLA-TSSSTQTFS
VTMSNQQQPQTISLNGQLFALQPVMSSSGTTNQTPMQIIQPTTSEDPNTNVALNTFGALA
SLNQSISQMAGQSCVQLSISQPANPPTAANSQTTPVNCVSLTTTVASPVTTDNSATLPSA
YSLVTTPSVNAVACLP-NMKSKRLNKKPGAKKHLAA-NKSACPLNPVRDAGKFDCASTDA
TAEPSCNNDGLLESLPVGLP-SVAGSQAN--------S------VRVSGAHSVDILNSES
-------------VIPESLPKSKSAEETSSPSQESVPSEHFVMTPAKSKDSAPILQRETP
QDKPPTSLALSDAAKSCASANVLIPSTNDPHVLVSQVSSLSSTASTAGTDCVSEVEVTAE
PCRVEQDS-PDTLQATGLLKGPGLTALLCGLEKEKDPQ--KLSLSVQVDHPDFSSENSK-
LVDAGVDLHP-KQELLLMSSDDRDPGPPHSCVPDPE-GIGGSLLVSRQADSPMSTSSGSS
RSFSVASMLPETTREDVSSSTT-TNTCDSCTFVEQTDIVALAARAIFDQDSLEKGRAGSQ
--ADVRDVTSKPAEASPLE--GDQPFKTQVSKESGAGQAEATPNEFTSQDSI---EATVD
--QPLGKPSCSVG-MKTSSASLQVSTSQPPSITSLSVNNLIHQSSSSHPLVSCAGLSQTS
EQTTVPATVTLTVASSSYTSQPPG-PALMTEYPQEQLSTITGT-IPNPQIQEPL-LKTSQ
ESRKDSAKRAVQDDLLLSSAKRQKHCQPAPLRLEAMSLMSRTPDSISDQAQMMVSQLPPN
SANSVVP--ISNPAHGDGLTRLFPPSNNFVAPALRQTEVQCSSQNSVAEQ---QQTQASQ
HLQALQQH--VPAQGVSHLHSNHLYLKQQQQQQQQ------------QQQQQQAVRERHH
LYQL-QHHIPHAESSVHSQPHNVHQQRTLQQEVQMQKKRNLVQGTQASQLALQPKHPGTD
QPRPKSGQPHPHHQQMQQQMQQHFGSSQPEKSCENPSASRNHH-SHPQSHLSQDLLHQQ-
PDVGSRQQGSGVSSEHVSGHNPMQRLLTSRGMEQ-QMVSQPSIVTRPSDMTCAPHRPERN
RVSSYSAEALIGKTSSNSEQRMGISIQGSRVSDQLEMRSYLDVPRNKSLALHNMQGRV--
DHPVAPE-IRLSDCQTFKPSGASQQPPSNFEVQSSRNNEIGNP-VSSLRTMQSQAFRISQ
NPGPPPVDRQKRLPYPPVQSIPAGNAIPP-RDSENTCHQSFMQSLLAPHLGDQVLGTQRP
LSEHQRNTQCGPSSAIEYNCPPAHESVHIRRESESQNRESCDMSLGAINTRNSTLNIPFS
SSSSSGDIQGRNTSPNVSVQKSNPMRITDSHGTKGHMNPPVTTNMHGVARPALPHPSVSH
GNAEQGP-PVRPTNSSVPQRSRHPLQDS-SGSKIRQPERNRSGNQRHSNVFDPSLPHLPL
STSGSMILGRQQPTTEKRGSIVRFMPDSPQIPNDNSAPDQHTLSQNFGFPFIPEGGMNPP
INANTSFIPQVTQPSATRTPALIPVDPQNTLPSFYPPYSPAHPTLSNDISIPYFSNQMFS
NPSTEKVNSGSLNNRFGSILSPPRPVGFAQPSFPLLPDMPPMHMTN-SHLSNFNMTSLFP
EIATAL-PDGSAMSPLLTIANSSASDSSKQSSNRPAHNISHILGHDCSSAV

----------------------MPEMTENETPTKKQHRKKNRETHNAVERHRKKKINAGI
NRIGELIPCSPALKQSKNMILDQAFKYITELKRQNDELLLNGGNNEQAEEIKKLRKQLEE
IQKENGRYIELLKANDICLYDDPTIHWKGNLKNSKVSVV---------------------
IPSDQVQKNIIVYSNGNQPGGNSQGTAVQGITFNVSHNLQKQTANVVPVQRTCNLVTPVS
ISGVYPSENKPWHQTTVPALATNQPVPLCLPAAISAQSILELPTSESESNVLGATSGSL-
-IAVSIESEPHQHHSLHTCLNDQNS---SENKNGQENPKVLKKMTPCVTNIPHSSSATAT
KVHHGNK---SC-LSIQDFRGDFQNTFVVS----VTTTVCSQPPRTAGDSS----PVSIS
KSADLTSTATVVASSAP-GVGKATIPISTLSGNPLDNGWTLSCSLPSSSVSTSDLKNINS
LTRISSAGNTQTTWTTLQLAGNTIQPLSQTPSSAVTPVLNESG--TSPTTSNHSRHVATG
I--NLNNSFPADGQPVEQVVVTLPSCPSLPMQPLIAQPQVKSQPPKNILPLNSAMQVIQM
AQPVGSAVNAAPTNQNVIILQPPSTTPCPTVMRAEVPNQTVGQQIVIIQAA-NQNPLPLL
PAPPPGSVRLPINGANTVIGSNNSVQNVPTPQTFGGKHLVHILPRPSSLS-ASNSTQTFS
VTMSN-QQPQTISLNGQLFALQPVMSSSGTTNQTPMQIIQPTTSEDPNTNVALNTFGALA
SLNQSISQMAGQSCVQLSISQPANSQTVANSQTTTANCVSLTTTAAPPVTTDSSATLAST
YNLVSTSSMNTVACLP-NMKSKRLNKKPGGRKHLAA-NKSACPLTSVRDVSKLDCPNTEG
SAEPPCN-DGLLESFPAVLP-SVSVSQAN---------SVSVSAS-----HSLGVLNSES
-------------LIPESVSKSKSAEKSSPPSQESVTSEHFAMAAAKSKDSTPNLQQETS
QDKPPSSSALSDAAKPCASANVLIPSPSDPHILVSQVPGLSSTASTTSTDCVSEVEIIAE
PCRVEQDS-SDTMQTTGLLKGQGLTTLLSDLAKKKNPQ--KSSLSDQMDHPDFSSENPK-
IVDSSVNLHP-KQELLLMNNDDRDPPQHHSCLPDQE-VINGSLITGRQADSPMSTSSGSS
RSFSVASMLPETTREDVTSNAT-TNTCDSCTFVEQTDIVALAARAIFDQENLEKGRVGLQ
--ADIREVASKPSEASLLE--GDPPFKSQIPKESGTGQAEATPNEFNSQGSI---EATME
--RPLEKPSCSLG-IKTSNASLQDSTSQPPSITSLSVNNLIHQSSISHPLASCAGLSPAS
EQTTVPATVNLTVSSSSYGSQPPG-PSLMTEYSQEQLSTMTST-IPNSQIQEPL-LKPSH
ESRKDSAKRAVQDDLLLSSAKRQKHCQPAPLRLESMSLMSRTPDTISDQTQMMVSQIPPN
SSNSVVP--VSNPAHGDGLTRLFPPSNNFVTPALRQTEVQCGSQPSV-AEQ--QQTQANQ
HLQALQQH--VPAQGVSHLHSNHLYIKQQQQQ---------------QQQQAGQLRERHH
LYQM-QHHVPHAESSVHSQPHNVHQQRTLQQEVQMQKKRNLVQGTQTSQLSLQPKHHGTD
QSRSKSGQPHPHHQQMQQQMQQHFGSSQTEKSCENPSTSRNHH-NHPQNHLNQDIMHQQ-
QDVGSRQQGSGVSSEHVSGHNPMQRLLTSRGLEQ-QMVSQPSIVTRSSDMTCTPHRPERN
RVSSYSAEALIGKTSSNSEQRMGISIQGSRVSDQLEMRSYLDVPRNKSLAIHNMQGRV--
DHTVTSD-IRLSDCQTFKPSGASQQPQSNFEVQSSRNNEIGNP-VSSLRSMQSQAFRISQ
NTGPPPIDRQKRLPYPPVQSIPTGNGIPS-RDSENTCHQSFMQSLLAPHLSDQVIGSQRS
LSEHQRNTQCGPSSAIEYNCPPTHENVHIRRESESQNRESCDMSLGVINTRNSTLNIPFS
SSSSSGDIQGRNTSPNVSVQKSNPMRITDSHATKGHMNPPVTTNMHGVARPALPHPSVSH
GNGDQGP-AVRQANSSVPQRSRHPLQDS-SGSKIRQPERNRSGNQRQSTVFDPSLPHLPL
STGGSMILGRQQPATEKRGSIVRFMPDSPQVPNDNSGPDQHTLSQNFGFSFIPEGGMNPP
INANASFIPQVTQPSATRTPALIPVDPQNTLPSFYPPYSPAHPTLSNDISIPYFPNQMFS
NPSTEKVNSGSLNNRFGSILSPPRPVGFAQPSFPLLPDMPPMHMTN-SHLSNFNMTSLFP
EIATAL-PDGSAMSPLLTIANSSASDSSKQSSNRPAHNISHILGHDCSSAV

----------------------MPEMTEHETPTKKQHRKKNRETHNAVERHRKKKINAGI
NRIGELIPCSPALKQSKNMILDQAFKYITELKRQNDELLLNGGSSEQAEEIKKLRKQLEE
IQKENGRYIELLKANDICLYDDPTIHWKGNLKTSKVSVV---------------------
IPSDQVQKNIIVYSNGSQPGGNSQGTAVQGITFNVGHGLQKQTANVVPVQRTCKLVTPVS
ISGVYPSENKPWHQTTVSALAANQSVPLCLPAAISAQNILELSTSESQSSGLGATGGSV-
-VTVSVGPDPHPHRSSNTCLNDQNA---SENNNAQESPKSSKKTVTCVSGISSSTSAAAP
EVHHENK---SS-PAMQGSSADSQNTL-VS----VTTTVCSQPPRSTGGSS----PVSGS
KTVDSPSTATVVVPAHA-AVAKSTLPVSSLSANPLEGGWTLSCSLPSSSVSASELKNISS
LTRISSAGNTQTTWTTLHLAGNTIQPLSQPPSSAATPALNECGTSP---TPNNHKHVATA
I--TLNNSPPTDGQPVEQVVVTLPSCPPLPMQPLIAQPQVKSQPPKNILPLNSAMQVIQM
AQPVGSGVTAAPANQNVIILQPPSTTPCPTMMRAEVSNQTVGQQIVIIQAA-NQNPLPLL
SAPHPGPVRLPVNGASAIIGSHNSVQNVPAPQTFGGKHLVHILPRPSSLS-TSNSTQTFS
VTMSNQQQPQTISLNGQLFALQPVMSSSGTTNQSPMQIIQPTTSEDPNTNVALNTFGALA
SLNQSISQMAGQSCVQLSISHSANPQTSANSQTSPANCVSLTTTVAPTITVDNSATPSTT
YSLATASSTNTVTCLPSTMKSKRLSKKPGAKKHLTA-NKPACPLNSVRDVGKIDGPRINS
SAEPSCS-DGLLDSLPVGLS-SVAVSQAK--------N------VSISASHSLDVLNSES
-------------VTPDSGPQSKSTEDCSSPSHESETNEQLVLAPAKPKDSTPILQ-ETS
QGTPPCSVALSNDMKSCTSANVLTPSPIESQSLVSQVSGLSSTTSTSSTDCISEVEIVAE
PCPVQQDS-LDTMQTAGSLKGQGLTMLLSDLAKEKDLQ--RSSLSVQMEHPDFSPESSK-
IGDSNVDLPP-KQELLLM-SDDRDPPQPHSCLPDQE-VLHGSLLTSRQADSPLSTSSGSS
RSFSVASMLPETAREDVTSSTT-SNTCDGCTFAEQTDIVALAARAILDQESIEKGRLGTQ
--ADVKEVTPKPSET-SLE--GDQPFKPQIHKETCTGQADPTPSEFNSQDSV---EVTVD
--RPLEKPSCSLG-IKGSNAPIQVSAPQPPSLTHQ-------NSISSHPLVSCTGLSQSS
DQTSNPVTVNMTVSSSSYGSQPPV-PPLMTEYPQEQLTSMTSA-IPNPQVQEPL-SKPSH
ESRKDSAKRTVQDDLLLNSAKRQKHCQPAPLRLESMPLMSRTPDNIPDQTQMMASQITPN
SSNSVVP--VSNPAHGDGLARLFPPSNNFVAPPLRQTDVQCNSQPSVAEQQQQQQTQAGQ
HLQALQQH--VPPQGVSHLHTNHLYIKQQ--------------------QQAGQLRERHH
LYQL-QHHVPHADSAVHSQPHIVHQQRTLQQEVQMQKKRNLVQGTPTSQLSLQPKHHGTD
QSRPKSSQPHPHHQQMQQQLQQHFASSQPEKSCENPSTNRGHH-SHPQNHLNQDVLHQQ-
QDVGSRQQG----SDHVSGHNPMQRLLPSRGLEQ-QMVSQPSIVTRSSDMTCAPHRPERN
RVSSYSAEALIGKSSSTSDQRMGISIQGSRVSDQLEMRSYLDVPRNKSLALHNMQGRM--
DHTVTSD-IRLSDCQTFKPGGASQQPQSNFEVQSSRNNEIGNP-VPSLRSMQSQAFRISQ
NTGPPPIDRQKRLSYPPVQSIPTGNAVPP-RDSENTCHQSFMQSLLAPHLGDQVIGSQRS
LSEHPRNTQCGPSSTIEYNCPPTRESVHIRRENESQNRESCDMSLGAINPRNSTLNIPFS
SSSSSGDIQGRNTSPNVSVQKSNPMRITDSHGAKGHMNPPVTSNMHGVARPTLPHPSVSH
GNADQGP-PVRQANSSVAQRSRHPLQDS-SGSKIRQPERNRSGNQRHSNVFDPSLPHLPL
STSGSMILGRQQPAAEKRGSIVRFMPDSPQVPNDNSGPDQHSLSQNFGFPFIPEGGMNPP
INANTSFIPQVTQPSATRAPALIPVDPQNTLPSFYPPYSPAHPTLSNDISIPYFSNQMFS
NPSTEKVNSGSLNNRFGSILSPPRPVGFAQPSFPLLPEMPPMHVAN-SHLSNFNMTSLFP
EIAAAL-PDGSAMSPLLTIANSSASDSSKQPSNRPAHNISHILGHDCSSAV

----------------------MPEMTEHETPTKKQHRKKNRETHNAVERHRKKKINAGI
NRIGELIPCSPALKQSKNMILDQAFKYITELKRQNDELLLNGGSSEQAEEIKKLRKQLEE
IQKENGRYIELLKANDICLYDDPTIHWKGNLKTSKVSVV---------------------
IPNDQVQKNIIVYSNGSQPGGNSQGTAVQGITFNVGHGLQKQTANVVPVQRTCKLVTPVS
ISGVYPSENKPWHQTTVSALAANQSVPLCLPAAISAQNILELSTSESQSSVLGATGGSV-
-VTVSVGPDPHPHRSLNTCLNDQNA---SENNNAQESPKSSKKTVPCVSGISSSNSAAAP
EVHHENK---SS-PAMQGSSADSQNTL-ES----VTTTVCSQPPRSTGGSS----PVSGS
KTVDSPSTATVVVPAHA-AVAKSTLPVSSLSANPLEGGWTLSCSLPSSSVSASELKNISS
LTRISSAGNTQTTWTTLHLAGNTIQPLSQPPSSAATPALNECGTSP---TPNNHKHVAAG
I--TLNNSPPTDGQPVEQVVVTLPSCPPLPMQPLIAQPQVKSQPPKNILPLNSAMQVIQM
AQPVGSGVTAAPANQNVIILQPPSTTPCPTMMRAEVSNQTVGQQIVIIQAA-NQNPLPLL
SAPHPGPVRLPVNGASAIIGSHNSVQNVPAPQTFGGKHLVHILPRPSSLS-TSNSTQTFS
VTMSNQQQPQTISLNGQLFALQPVMSSSGTTNQSPMQIIQPTTSEDPNTNVALNTFGALA
SLNQSISQMAGQSCVQLSISHSANPQTSANSQTSPANCVSLTTTVAPTITADNSATPSTT
YSLATASSTNTVTCLPSTMKSKRLSKKPGTKKHLTA-NKPACPLNSVRDVGKIDGPRINS
SAEPSCS-DGLLDSLPVGLS-SVAVSQAK--------N------VSMSASHSLDVLNSES
-------------VTPDSGPQSKSTEDCSSPSQEPETNEQLVLAPAKPKDSTPILQ-ETS
QGTPPCSVALSNAMKSCTSANVLTPSPIESQSLVSQVSGLSSTTSTSSTDCISEIEIVAE
PCPVQQDS-LDTMQTAGSLKGQGLTMLLSDLAKEKDLQ--RSSLSVQMEHPDFSPESSK-
IGDSNVDLPP-KQELLLM-SDDRDPPQPHSCLPDQE-VLHGSLLTSRQADSPLSTSSGSS
RSFSVASMLPETAREDVTSSTT-SNTCDGCTFAEQTDIVALAARAILDQESIEKGRLGTQ
--ADMKEVTPKPSET-SLE--GDQPFKPQIHKETCTGQADPTPSESNSQDSV---EVTVD
--RPLEKPSCSLG-IKGSNAPIQVSAPQPPSLTHQ-------NSISSHPLVSCTGLSQSS
DQTSNPVTVNMTVSSSSYGSQPPV-PPLMTEYPQEQLNSMTSA-IPNPQVQEPL-SKPSH
ESRKDSAKRTVQDDLLLSSAKRQKHCQPAPLRLESMPLMSRTPDNIPDQTQMMASQITPN
SSNSVVP--VSNPAHGDGLARLFPPSNNFVAPTLRQTDVQCNSQPSVAEQQQQQQTQAGQ
HLQALQQH--VPPQGVSHLHTNHLYIKQQQ------------------QQQAGQLRERHH
LYQL-QHHVPHADSAVHSQPHIVHQQRTLQQEVQMQKKRNLVQGTPTSQLSLQPKHHGTD
QSRPKSSQPHPHHQQMQQQLQQHFASSQPEKSCENPSTNRGHH-SHPQNHLNQDVLHQQ-
QDVGSRQQG----SDHVSGHNPMQRLLPSRGLEQ-QMVSQPSIVTRSSDMTCAPHRPERN
RVSSYSAEALIGKSSSTSDQRMGISIQGSRVSDQLEMRSYLDVPRNKSLALHNMQGRM--
DHTVTSD-IRLSDCQTFKPGGASQQPQSNFEVQSSRNNEIGNP-VPSLRSMQSQAFRISQ
NTGPPPIDRQKRLSYPPVQSIPTGNAVPP-RDSENTCHQSFMQSLLAPHLGDQVIGSQRS
LSEHPRNTQCGPSSTIEYNCPPTRESVHIRRESESQNRESCDMSLGAINPRNSTLNIPFS
SSSSSGDIQGRNTSPNVSVQKSNPMRITDSHGAKGHMNPPVTSNMHGVARPTLPHPSVSH
GNADQGP-PVRQANSSVAQRSRHPLQDS-SGSKIRQPERNRSGNQRHSNVFDPSLPHLPL
STSGSMILGRQQPAAEKRGSIVRFMPDSPQVPNDNSGPDQHSLSQNFGFPFIPEGGMNPP
INANTSFIPQVTQPSATRAPALIPVDPQNTLPSFYPPYSPAHPTLSNDISIPYFSNQMFS
NPSTEKVNSGSLNNRFGSILSPPRPVGFAQPSFPLLPEMPPMHMAN-SHLSNFNMTSLFP
EIAAAL-PDGSAMSPLLTIANSSASDSSKQPSNRPAHNISHILGHDCSSAV

----------------------MPEMTENETPTKKQHRKKNRETHNAVERHRKKKINAGI
NRIGELIPCSPALKQSKNMILDQAFKYITELKRQNDELLLNGGNNEQAEEIKKLRKQLEE
IQKENGRYIELLKANDICLYDDPTIHWKGNLKSSKVSVV---------------------
IPSDQVQKNIIVYSNGSQPGGNSQGTAVQGITFNVGHNLQKQTANVVPVQRTCNLVTPVS
ISGVYPSENKPWHQTTVSALAANQPVPLCLPATISTQNILELSTSESESSVLGATSGSL-
-IAVSVGPEPPQHRSLHTSLNDQNS---SENKNGQESPKLLNKTVPCATSIPSSSSATAT
KVNYGGK---SC-LSIQDFTSDFQTTFVVS----VTTTICSQPPRSAGDSC----PVVIS
KGAGSTSVTTVVAPSAP-GGGKTTTSVGSLSANPLDNSWTLSCSLPSSAVSASDLKNINS
LTRISSAGNTQTTWTTLQLAGNTIQPLSQTPSSALTPVLNESG--TSPTTTSHSRHVATG
I--NLNNSFPVDGQPVEQVVVTLPSCPSLLMQPLIAQPQVKYQPPKNILPLNSAMQVIQM
GQPVGSDVNAAPANQNVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXX-XXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTNVALNTFGALA
SLNQSISQMAGQSCVQLSVSQPANPQTAANGQTTPANCVSLTATVASPMTTDNSATLPSI
YNLVTTPSVNTVAGLP-NVKSKRLNKKPGVKKHLVA-NKSVCSLNPVRDVGKADCPSTEG
LAGPPCN-DGLLESPPVVLP-SVTMSQAK--------STVSVSGS-----HSLDVPNSES
-------------AIPESVPKSKSAEESSLSSQESVTSEHFAMAPAKSKDSAPVLQRETS
QDKPPTSLALPDAAKSCTSANVLIPSPSDAHILVSQVSGLSSTMSTVSTDCVSEVEIIAE
PCRVEQDS-SDTMQTTGLLKGQGLTALLSGFAKEKDPQ--K-SLSVQVDHPDFSSENSK-
TVDSSVDLHP-KQDLLLMSSDDRDPGQHPSCISDQE-VIHGSLLTSRQTDSPMSTSSGSS
RSFSVASMLPETTREDVTSNAT-TNTCDSCTFVEQTDIVALAARAIFDQENLEKGRAGTQ
--ADLREVTSKPSEASSLE--GDQPFKAQTSKDNGPGQAEATPNEFNSQESI---EVTMD
--RPLEKSSCSAG-IKTSTASLQVSTSQPPSITSLSVNNLIHQSSISHPLVSCAGLSQTS
EQTTIPATVNLTVSSTSYGNQPPG-PSLITEYSQEQLNTMTGT-IPNPQIQEPL-LKPGH
ESRKDSAKRAVQDDLLLSSAKRQKHCQPAPLRLEGMSLMSQTPDSISDQTQMMVSQIPPN
SSNSVVP--ISNPAHGDGLTRLFPPSNNFLAPALRQTEVQCSS--SV-AEQ--QQTQAGQ
HLQALQQH--VPAQGVSHLHSNHLYLKQQQQQQQQQQQ--QQQQQQQQQQQAGQLRERHH
LYQL-QHHIPHAETSVHSQPHNVHQQRTLQQEVQMQKKRNLVQGAQASQLSLQPKHHGTD
QSRPKSGQSHPHHQQIQQQMQQHFGSSQPEKSCENPSTSRNHH-NHPQNHINQDIMHQQ-
QDVGSRQQGSGVSSEHVSGHNPMQRLLTSRGIEQ-QMVSQPSIVTRPSDMTCTPHRPERN
RVSSYSAEALIGKTSSNSEQRMGILIQGSRVSDQLEMRSYLDVPRNKSLAIHNMQGRV--
DHTVASD-IHLSDCQTFKPSGASQQPQSNFEVQSSRNNEIGNP-VSSLRSMQSQAFRISQ
NPGPPPIDRQKRLPYPPVQSIPTGNAIPP-RDSENTCHQSFMQSLLAPHLGDQVIGSQRS
LSEHQRNTQCGPSPAIEYNCPPAHESVHIRRENENQNRESCDMSLGAINTRNSTLNIPFS
SS-SSGDIQGRNTSPNVSVQKSNPMRITDSHGTKGHMNPPVTTNMHGVARPALPHPSVSH
GNTDQGP-PVRQTSSSVPQRSRHPLQDS-SGSKIRQPERNRSGNQRHSNVFDPSLPHLPL
STSGSMILGRQQPTTEKRGSIVRFMPDSPQVPNDNSVPDQHTLSQNFGFPFIPEGGMNPP
INANTSFIPQVTQPSATRTPALIPVDPQNTLPSFYPPYSPAHPTLSNDISIPYFSNQMFS
NPSTEKVNSGSLNNRFGSILSPPRPVGFAQPSFPLLPDMPPMHMTN-SHLSNFNMTSLFP
EIATAL-PDGSAMSPLLTIANSSASDSSKQSSNRPAHNISHILGHDCSSAV

----------------------MPEMTENEMPTKKQHRKKNRETHNAVERHRKKKINAGI
NRIGELIPCSPALKQSKNMILDQAFKYITELKRQNDELLLNGGNNEQAEEIKKLRKQLEE
IQKENGRYIELLKANDICLYDDPTIHWKGNLKNSKVSVV---------------------
IPSDQVQKNIIVYSNGNQPGGNSQGTAVQGITFNVSHNLQKQTANVVPVQRTCNLVTPVS
ISGVYPSENKPWHQTTVPALATNQPVPLCLPAAISAQSILELPTSESESNVLGATSGSM-
-IAVSIGSEPHQHHSLHTCLHDQNS---SENKNGQENPKLLKKMTPCVTNMPHSSSATAT
KVHHGNK---SC-LSIQDFRGDFQNTFVVS----VTTTVCSQPPRTADDSS----PVSIS
KSADLTSTATVVASSAP-GVGKATIPISTLSGNPLDNGWTLSCSLPSSSVSTSDLKNINS
LTRISSAGNTQTTWTTLQLAGNTIQPLSQTPSSAVTPVLNESG--TSPTTSNHSRHVATG
I--NLNNSFPADGQPVEQVVVTLPSCPSLPMQPLIAQPQVKSQPPKNILPLNSAMQVIQM
AQPVGSAVNAAPTNQNVIILQPPSTTPCPTVMRAEVPNQTVGQQIVIIQAA-NQNPLPLL
PAPPPGSVRLPINGANTVIGSNNSVQNVSTPQTFGGKHLVHILPRPSSLS-VSNSTQTFS
VTMSN-QQPQTISLNGQLFALQPVMSSSGTTNQTPMQIIQPTTSEDPNTNVALNTFGALA
SLNQSISQMAGQSCVQLSISQPANAQTAANSQTTTANCVSLTTTAAPPVTTDSSATLAST
YNLVSTSSMNTVACLP-NMKSKRLNKKPGARKHLAA-NKSACPLNSVRDVSKLDCPNSEG
SAEPPCN-DGLLESFPVVLP-SVSMSQAN---------SVSVSAS-----HSLGVLSSGS
-------------LIPESVLKSKSPEKSSSPSQDSVTSEHFAMAAAKSKDSTPNLQQETS
QDKPPSSLALSDAAKPCTSANVLIPSPSDPHILVSQVSGLSSTTSTTSTDCVSEVEIIAE
PCRVEQDS-SDTMQTTGLLKGQRLTTLLSDVAKKKTPQ--KSSLSDQMDHPDFSSENPK-
IVDSSVNLHP-KQELLLMNNDDRDPPQHHSCLPDQE-VINGSLITGRQADSPMSTSSGSS
RSFSVASMLPETTREDVTSSAT-TNTCDSCTFVEQTDIVALAARAIFDQENLEKGRVGLQ
--ADIREVASKPSEASLLE--GDPPFKSQIPKENGTGQAEATPNEFNSQGSI---EATVE
--RPLEKPSCSLG-IKTSNASLQDSTSQPPSITSLSVNNLIHQSSISHPLASCAGLSPTS
EQTTVPATVNLTVSSSSYGSQPPG-PSLMTEYSQEQLNTMTST-IPNSQIQEPL-LKPSH
ESRKDSAKRAVQDDLLLSSAKRQKHCQPAPVRLESMSLMSRTPDTISDQTQMMVSQIPPN
SSNSVVP--VSNPAHGDGLTRLFPPSNNFVAPALRQTEVQCGSQPSV-AEQ--QQTQASQ
HLQALQQH--VPAQGVSHLHSNHLYIKQQQQ---------------QQQQQAGQLRERHH
LYQM-QHHVPHAESSVHSQPHNVHQQRTLQQEVQMQKKRNLVQGTQTSQLSLQPKHHGTD
QSRSKSGQPHPHHPQMQQQMQQHFGGSQTEKSCENPSTSRNHH-NHPQNHLNQDIMHQQ-
QDVGSRQQGSGVSSEHVSGHNPMQRLLTSRGLEQ-QMVSQPSIVTRSSDMTCTPHRPERN
RVSSYSAEALIGKTSSNSEQRMGISIQGSRVSDQLEMRSYLDVPRNKNLAIHNMQGRV--
DHTVASD-IRLSDCQTFKPSGASQQPQSNFEVQSSRNNEIGNP-VSSLRSMQSQAFRISQ
NTGPPPIDRQKRLPYPPVQSIPTGNGIPS-RDGENTCHQSFMQSLLAPHLSDQVIGSQRS
LSEHQRNTQCGPSSAIEYNCPPTHENVHIRRESESQNRESCDMSLGAINTRNSTLNIPFS
SSSSSGDIQGRNTSPNVSVQKSNPMRITDSHATKGHMNPPVTTNMHGVARPALPHPSVSH
GNGDQGP-AVRQANSSVPQRSRHPLQDS-SGSKIRQPERNRSGNQRQSSVFDPSLPHLPL
STGGSMILGRQQPATEKRGSIVRFMPDSPQVPNDNSGPDQHTLSQNFGFSFIPEGGMNPP
INANASFIPQVTQPSATRTPALIPVDPQNTLPSFYPPYSPAHPTLSNDISIPYFPNQMFS
NPSTEKVNSGSLNNRFGSILSPPRPVGFAQPSFPLLPDMPPMHMTN-SHLSNFNMTSLFP
EIATAL-PDGSAMSPLLTIANSSASDSSKQSSNRPAHNISHILGHDCSSAV

----------------------MPEMTEHETPTKKQHRKKNRETHNAVERHRKKKINAGI
NRIGELIPCSPALKQSKNMILDQAFKYITELKRQNDELLLNGGNNEQAEEIKKLRKQLEE
IQKENGRYIELLKANDICLYDDPTIHWKGNLKNSKVSVV---------------------
IPSDQVQKNIIVYSNGSQPGGNSQGTAVQGITFNVSHNLQKQTANVVPVQRTCNLVTPVS
ISGVYPSENKPWHQTTVSALAANQPVPLCLPATISAQNILELSTSESESSVLGATGSSL-
-IAVSVGSEPHQHQSLHTGLNDQNS---SETNNGQESPKLLKRTAPCVTSVPPSSSASAT
KVHCGTK---SC-LSTQDFRGDFQNTFVVS----VTTAVCSQLPRSAGDSS----PVSVS
KCTISTSTTSVVAPSAS-GVEKTTTPVSTLSTNPLDSGWTLSCSLPSSSVSASDLKNINS
LTRISSAGNTQTTWTTLQLAGNTIQPLSQTPSSTVIPVLNESG--PSPTASNHSRHMATS
I--NLNNSLPTDGLSVEQVVVTLPSCPSLPVQPLIAQPQIKSQPPKNILPLNSAMQVIQM
AQPVGSAVNATPANQNVIILQPPSTTPCPTVVRAEVPNQTVGQQIVIIQAA-NQNPLPLL
SAPPPASVRLPVNGASAIIGSNHSVQNVSTPQTFGGKHLVHILPRPSSLS-TSHSTQTFS
VTMSNQQQPQTISLNGQLFALQPVMSSSGTTNHTPMQIIQPTTSEDPNTNVALNTFGALA
SLNQSISQMAGQSCVQLSLSQPANSQIAANSQTSPTNCVSLTTTVAPPMTTDNSAIPPGT
FNLMTTSSMNTVACLPPTTKSKRLNKKPGAKKHIAA-SKPTCPLNPVREVGKSDCPNMES
AAEPSCT-PGLLESLPVVLP-PVTLSQAN--------S------GSVSASHSLDMLNSES
-------------VIPESVSKSKSAEESSSPSQESGTSEHCTVAPAKSKDSTPILQGETS
QDKPPTSLALSDATKSCTSANVLIPSPN-PQILVSQVSGLSSSTRTTSTDCVSEVEIIAE
PCRIEQES-SDTMQTAGLLKGQGLTTLLSDVAKEKDPQ--KSTLSDPMDHPDFSSENSK-
IIDSSVDLQP-KQELLLMNNDDRDPPQHQSCLPDQE-VINGSLLTSRQADSPSSTSSGST
RSFSVASMLPETTREDVTSSTS-TNTCDSYTFAGQPDIVALAATVIFGHHNIEKGRVGIQ
--ADVREGTSKPSEASSLE--GDQSFKSQIPKENGTGQTEATPNELNSQDSI---EVTVD
--RPLEKPSCSLG-IKTSNGSLQVSTSQPPSLTSLSVNNLIHQSSISHPLVSCAGLSQTS
EQTTASATVNLTVSSSSYSSQPPG-PPLMTEYSQDQLSTMNNT-IPNSQIQESL-LKPSH
ESRKDSAKRSVQDDLLLSSAKRQKHCQPVPLRLENMSLMSGTPDSISDQTQMMVSQLPPN
SSNSVVP--VSNPAHGDGLTRLFPPGNNFVSPALRQAEVQCSSQPSV-AEQ--QQTQASQ
HLQALQQH--VPAQGVSHLHSNHLYIKQQQQ------------------QQAGQLRERHH
LYQL-QHHVPHAETAVHSQPHNVHQQRTLQQEVQMQKKRNLVQGSQASQLSLQPKHHGTD
QARPKSGQPHPHHQQMQQQMQQHFGSSQPEKSCENPSTSRNHH-SHPQNHLNQDIMHQQ-
QDVGSRQPGSGISSEHVSGHNPMQRLLTSRGLEQ-QMVSQSSIVTRPSDMTCTPHRPERN
RVSSYSAEALIGKTSSNSEQRMGISIQGSRVSDQLEMRSYLDVPRNKSLAIHNMQGRV--
DHTVASD-IRLSDCQTFKPSGAGQQPQNNFEVQSSRNNEIVNP-VSSLRSMQSQAFRISQ
NTGPPPIDRQKRLPYPPVQSIPTGNAIPP-RDSENTCHQSFMQSLLAPHLGDQVIGSQRS
LSEHQRNTQCGPSSAIEYNCPPAHESVHIRRESENQNRESCDMSLGAINTRNNSLNIPFS
SSSSSGDIQGRNTSPNVSVQKSNPMRITDSHGTKGHMNTPVTTNMHGVARPALPHPSVSH
GNADQGP-PVRQANSSVPQRSRHPLQDS-SGSKIRQPERNRSGNQRHSNVFDPSLPHLPL
STSGSMILGRQQPTTEKRGSIVRFMPDSPQVPNDNSGPDQHTLSQNFGFPFIPEGGMNPP
INANTSFIPQVTQPSATRTPALIPVDPQNTLPSFYPPYSPAHPTLSNDISIPYFSNQMFS
NPSTEKVNSGSLNNRFGSILSPPRPVGFAQPSFPLLPDMPPMHMTN-SHLSNFNMTSLFP
EIATAL-PDGSAMSPLLTIANSSASDSSKQSSNRPAHNISHILGHDCSSAV

----------------------MPEMTEHETPTKKQHRKKNRETHNAVERHRKKKINAGI
NRIGELIPCSPALKQSKNMILDQAFKYITELKRQNDELLLNGGSSEQAEEIKKLRKQLEE
IQKENGRYIELLKANDICLYDDPTIHWKGNLKTSKVSVV---------------------
IPSDQVQKNIIVYSNGSQPGGNSQGTAVQGITFNVGHGLQKQTANVVPVQRTCKLVTPVS
ISGIYPSENKPWHQTTVSALAANQSVPLCLPTAISAQNILELSTSESQSSALGATGGSV-
-VTTSVGPDPHQHRSLNTCLNDQNA---SENSNVQESPKSSKKTVSSVSGTSSSNSAAAP
GVHHETK---SS-LATQGSSADSQNTL-VS----ITTPVSSQPPRSTGSSS----PVSVS
KTVDPTNTAAAVVPAHT-AVSKSALPVSSLSATPLEGGWTLSCSLPSSSVSASELKNINS
LTRISSAGNTQTTWTTLHLAGNTIQPLSQPPSSASTPALNECGTSP---TPSNHKHMATG
I--TFNNSPPTDGQPVEQIVVTLPSCPPLPMQPLIAQPQVKSQPPKNILPLNSAMQVIQM
AQPVGSGVTAAPANQNVIILQPPSTTPCPAMMRAEVSNQAVGQQIVIIQAA-NQNPLPLL
SAPHPGPVRLPVNGASAIIGSHNSVQNVPAPQTFGGKHLVHILPRPSSLS-TSNSAQTFS
VTMSNQQQPQTISLNGQLFALQPVMSSSGTTNQSPMQIIQPTTSEDPNTNVALNTFGALA
SLNQSISQMAGQSCVQLSISQSANPQTSANSQTSPTNCVSLT-TVAPTMTAENSATQSTT
YSLATASSTNTVTCLPSTMKSKRLSKKPSAKKHLAA-NKPACPLNSVRDVGKMDGPGMDS
SAEPSCS-DGLLNGLPVGLS-SVTVSQAK--------S------VSISASHSLDILNSES
-------------VIPESDSKSKSAEDCSSSSRESEANEQLALATAKSKDSTPILQ-ESS
QGTPPCSVALPNATKSCASANVLTPSPTESESLVSQVSGMPSTTSTSNTVCISEVEIVAE
PCPVQQES-LDTMQAAGPLKGQGLTMLLSDLAKEKDLQ--RTSLPVQMDHPDFSPESSK-
IGDPNVDLHP-KQELLLT-SDDRDLPQPHSCLPDQE-VIHGSLLTSRQADSPMSTSSGSS
RSFSVASMLPETAREDVTSS-T-TNTCDSCTFAEQTDIVALAARAILDQESIEKGRLGTQ
--ADLKDVTPKPSET-SLE--GDQPFKPQIHKETCTGQADPTPNEFNSQDSV---EVTVD
--RPLEKPSCSLG-IKASNPPLQVSASQPPSL--------THQNSISRPLVSCAGLSQSS
DQTAIPVTVNMTVASSAYGSQPPV-PPLMTEYSQEQLNSMANS-IPNPQVQEPL-SKPSH
ESRKDSAKRTVQDDLLLSSAKRQKHCQPAPLRLESVPLMSRTPDNIPDQTQMMASQITPN
SSNSVVP--VSNPAHGDGLTRLFPAGNNFAAPVLRQADVQCNPQPSVAEQP--QQTQAGQ
HLQALQQH--VPPQGVSHLHTNHLYLKQQQQQ-----------------QQAGQLRERHH
LYQL-QHHVPHADNAVHSQPHIVHQQRTLQQEVQMQKKRNLVQGTPTSQLSLQPKHHGTD
QSRPKSSQPHPHHQQMQQQLQQHFASSQPEKSCENPSSSRGHH-SHPQNHLNQDVLHQQ-
QDVGSRQQGSAVSSDHVSGHNPMQRLLPSRGLEQ-QMVSQPSIVTRSSDMTCAPHRPERN
RVSSYSAEALIGKSSSTSEQRLGISIQGSRVSDQLEMRSYLDVPRNKSLALHNMQGRM--
DHTVTSD-IRLSDCQTFKPGAASQQPQSNFEVQSSRNNEIGNP-APSLRGMQSQAFRISQ
NTGPPPIDRQKRLSYPPVQSIPTGNAVPP-RDSENTCHQSFMQSLLAPHLGDQVIGSQRS
LSEHPRNTQCGPSSTIEYNCPPARESVHIRRESESQNRESCDMSLGAINPRNSTLNIPFS
SSSSSGDIQGRNTSPNVSVQKSNPMRITDSHGAKGHMNPPVTSNMHGVARPTLPHPSVSH
GNADQGP-PVRQANSSVAQRSRHPLQDS-SGSKIRQPERNRSGNQRHSNVFDPSLPHLPL
STSGSMILGRQQPAAEKRGSIVRFMPDSPQVPNDNSGPDQHSLSQNFGFPFIPEGGMNPP
INANTSFIPQVTQPSATRAPALIPVDPQNTLPSFYPPYSPAHPTLSNDISIPYFSNQMFS
NPSTEKVNSGSLNNRFGSILSPPRPVGFAQPSFPLLPEMPPMHMAN-SHLSNFNMTSLFP
EIAAL--PDGSAMSPLLTIANSSASDSSKQSSNRPAHNISHILGHDCSSAV

----------------------MPEMTENETPTKKQHRKKNRETHNAVERHRKKKINAGI
NRIGELIPCSPALKQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXNGRYIELLKANDICLYDDPTIHWKGNLKNAKVSVV---------------------
IPSDQIQKNIIVYSNGSQPGGNNQGTAVQGITFNVGHNLQKQTANVVPVQRTCNLVTPVS
ISGVYPPENKPWHQTTVSSLAASQSVPLCLPATIPAQNILEISTSESESSVLSSNNSQT-
--TIPSGSESHIQRS-------SSSQSGSESKNGQESPKLLKRPVSCATSIPPNTSVLSF
QVQHGNK---SC-LSLQDFRSDCQDNFVAP----VADTAFSQPLRTSVPMN--SSPVNIS
KNTELTNNGGIEAPSVA-LAVKAATAISTVSASHLDSGWSLSCSLPSSSVNASDLKNISS
LTRIPSSGNTQTTWTTLQLAGNTVQPLSQAPSTIVTPILNEPGTGT--STTNHNRHMTTC
VLNGLNGSFPTDGQQVEQVVVTLPSCPSLPMQPLIAQPPIKTQPPPNILPFNSTMQVIQM
AQPVGSAVNAGPANQNVIILQPPNTTPCPGVMRAEVPNQTVGQQIVIIQAA-NQNPLPLL
SAPPPGSVRVSVNGANPVVVSNNSVQNVSAPQTFGGKHLVHILPRPSLSS-SSNSTQTFS
VTMSNQQQPQTISLNGQLFALQPIMSSSGATNQTPMQIIQPTTSEDPNTNVALNTFGALA
SLNQSISQMAGQSCVQLAISPPTNPSPATNSRLTPVNCVSLPTTAASPVTTDNTAVLSNT
ANQI-TCTVKALASLPSNVKSKRVNKKPGPKKHVA--NKSSCPVNPVRDSGKSDCANTEG
STQQSCA-DGLLESLPVVLT-PADESQ--------------VNSISVSDSHSFESVNSEP
-------------VVSESNPLE---MSHSPPSQEPVTSEHFVLAPPDSRDTLSTLQSGRS
QSKPTP--ELSDSSKSCISSGILIPSPNDPHILVSQIPGSSSTQSTTSTNGASEVEIIAE
PCRQDS---SAAVQATGLLKGHGLTALLSDLTKEKESQ--KTHLSAQVNHPNFPSENSK-
IIDSSIDLPQ-KQELLLINGEGGNLPQHHSCIPDQE-AINSSLLASRQTDSPMSTSSGSS
RGFSVASMLPDTTREDVTNSTS-TNTCDSCTFAEQTDIVALAARAIFDQENIEKGRVGVQ
--ADVQETAPKPSETLSSE--GDQSFKTQAAKENTTGQVEATANEFSSQDPV---QANV-
-DRSLEKPSCSVS-TETSNASIQVSTSQSSSISSLSVNNLIHQSNISHPLVSCS------
EQPAIPATVNLSVSSSSYASQPPE-PSLMTEYSQDQLNTMTSN-IPNSQIQESH-LKSSH
ESRKDPAKRPVQDDLLLSTAKRQKHCQPAPLRLEGMSLMSRTPDSIADQTQMMVGQIPPN
SSNSVVP--VSNPGHVDDLSRLFPPSNSFVTPALRQTEVQCNSQPSMTEQQ--QSQTGSQ
HLQPLQQH-VPPAQGISHLHNNHPYLKQQ--------------------QQAGQLRERHH
LYQL-QHHVSHADSSIHSQPHSVHQQRTIQQEVQMQKKRSLVQGTQAPQLSIQQKHHGSD
QSRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXX--XXXXXXXXXX-
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXNSSVTQRSRHPQDSS-GGSKIRQ-ERNRSGNQRHNNVFDPSLPHLPL
STSGSMIIGRQQSSTEKRGSIVRFMRDSPQVSNDSTAPDQHTLSQNFGFPFIPEGGMNPP
INANTSFIPQVTQPSATRTPALIPVDPQNTLPSFYPPYSPAHPTLSNDISIPYFSNQMFP
NPSTEKVNSGGLNNRFGTILSPPRPVGFAQPSFPLLPEMPPMHMTN-SHLSNFNMTSLFP
EIATAL-PDGSAMSPLLTLANSSASDSSKQTSNRPAHNISHILGHDCSSAV

----------------------MPEMTEHETPMKKQHRVANVFLLFLVERHRKKKINAGI
NRIGELIPCSPALKQSKNMILDQAFKYITELKRQNDELLLNGGNSEQAEEIKKLRKQLEE
IQKENGRYIELLKANDICLYDDPTIHWKGNLKNSKVSVV---------------------
IPSDQVQKNIIVYSNGSQPGGNSQGTAVQGITFNVGHSLQKQTANVVPVQRTCKLVTPVS
ISGVYPSENKPWHQTTVSALAANQPVPLCLPAAISAQNILELSTSESQSSVLGATGGPL-
-ITVAVGPDPHQHRPLHTCLNDQNA---PENNNGQESPKSSKKTVACVTSISSGNSAAAS
NVHHETK---SG-PGVQDFSEDLQNTLAVS----ATSTACSEPPRCMGDSS----PGSIS
KTADSTNTTTVVAPAHA-GVVKTTLPVSSLSANPLDSGWTLSCSLPSSSVSASDLKNITS
LTRISSAGNTQTTWTTLHLAGNTIQPLSQTPSSAVTPVLSESGTSP---TPSHHKHVATG
I--TLNTSLPADGPPAEHVMVTLPSCPPLPMQPPTAQPQVKSQPPKNILPLNSAMQVIQM
AQPVGSAVTAAPGNQNVIILQPPSTTPCPAMMRAEVPSQAVGQQIVIIQAA-NQNPLPLL
SAPHPGPVRLPVNGASAIIGSHNSVQNVPAPQTFGGKHLVHILPRPSSLS-MSNSTQTFS
VTMSNQQQPQTISLNGQLFALQPVMSSSGTTNQTPMQIIQPTTSEDPNTNVALNTFGALA
SLNQSISQMAGQSCVQLSISQSANPQTPANSQTSPANGVPLATTVAPPVTTENSATLAST
YSLTTASSTNPVTCLPPTMKSKRLNKKPGAKKHAA--NKPACPPNSVRDVGKLDGPRTDS
SAQLSCS-DGLLDSLPVSLA-SAAVSQAK--------S--------VSSSAPLAILNSDS
-------------VAPESVSRSKSAEDCSSSSQESETSEQSAVDPAKSKDSTPILQ-ETS
QGTPPTAVALSSAAKSCTTTNVLIPSPIESQIVVSQVSGMSSTTSTSSTDCISEVETVAE
PCPVQQDA-LDTMQTPGPLKGQGLTMLLSDLTKEKDLQ--KSSLSVQMDHPDFSPEDSK-
LGDSNVELHP-KQELLLL-SDDRDPAQHRPCLPDQE-AINGSLLPSRQADSPMSTSSGSS
RSFSVASMLPETAREDVTSSTT-TNACDSCTFAEQTDIVALAARAILDQESIEKGRVGTQ
--AEMREVTSKPSET-SLE--GEQPFKPQVHKEPCTGQADATPNEFNSQDSV---EVTVD
--RPLEKPSCSLG-IKTSNASLQVSASQPPSLTSL-------SSSINHPLVSCTGLSQPS
EQTSIPVTVNMTVASSSYGSQPPV-PPLMTEYSQEQLNSMTSA-IPNPQLQEPL-PKPSH
ESRKDSAKRTVQDDLLLSSAKRQKHCQPAPLRLESMPLMSRTPDSIPDQTQMMVSQIPTN
SSNSVVP--ASNPAHGDGLTRLFPPGNNFVAPALRQTEVPCSSQPPVAEQQ--QQTQASQ
HLQALQQH--VPSQGVSHLHSNHLYIKQQQQQQQQQ-------QQQQQQQQAGQLRERHH
LYQL-QHHVPHADSAVHSQPHI--------------------------------------
---------------------QHFASSQPEKSCENSSTNRGHH-SHAQNHLNQDILHQQ-
QDVGSRQQGSAVSSDHVSGHNPMQRLLPSRGLEQ-QMVSQPSIVTRSSDMTCAPHRPERN
RVSSYSAEALIGKSSSTSEQRMGMSIQGSRVSEQLEMRSYLDVPRNKSLALHNMQGRM--
DHP-----VPLPDCQTFKPAGASQQPQSNFEVQSSRNNEIGNP-VPSLRSMQSQAFRISQ
NTGPPPIDRQKRLSYPPVQSIPTGNTVPP-RDNENTCHQSFMQSLLAPHLGDQVLGSQRS
LSEHSRNTQCGPSSTIEYNCPPARESVHIRRESESQNRESCDMSLGTINTRNSTLNIPFS
SSSSSGDIQGRNTSPNVSVQKSNPMRITDSHGTKGHMNPPVTSNMHGVARPTLPHPSVSH
GNADQGP-PVRQANSSVVHRSRHPLQDS-GGSKIRQPERNRSGNQRHSNVFDPSLPHLPL
STSGSMILGRQQPAAEKRGSIVRFMPDSPQVPNDNSGPDQHTLSQNFGFPFIPEGGMNPP
INANTSFIPQVTQPSATRTPALIPVDPQNTLPSFYPPYSPAHPTLSNDISIPYFSNQMFS
NPSTEKVNSGSLNNRFGSILSPPRPVGFAQPSFPLLPEMPPMHMAN-SHLSNFNMTSLFP
EIATAL-PDGSAMSPLLTIANSSASDSSKQSSNRPAHNISHILGHDCSSAV

----------------------MPEMTEHETPTKKQHRKKNRETHNAVERHRKKKINAGI
NRIGELIPCSPALKQSKNMILDQAFKYITELKRQNDELLLNGGNNEQAEEIKKLRKQLEE
IQKENGRYIELLKANDICLYDDPTIHWKGNLKNSKVSVV---------------------
IPSDQVQKNIIVYSSGSQPGGNSQGTAVQGITFNVGHNLQKQTANVVPVQRTCNLVTPAS
VSGIYPSEKKPWHQTTVSALAANQPVPLCLPAAISAQNILELSTSESESSVLGASGGSL-
-IAVSVGPELHQYPSSHICTNDQNS---SENNSGLDSTKLLKKTAPCVTSVSPSSSATTT
KVHHGIK---SC-LSLQNCRGDFQNTFVVS----VTTTICSQPPRSSGDSS----PL---
---------------------------------------------SISNASASDLKNINS
LTRISSAGNTQTTWTTLQLAGNTIQPLSQTPSSTVTPVLSESS--TSPPTSNHSRHVATG
I--NLNNSLPADGQPVEQVVVTLPSCPPLLMQPLISQPQVKSQPPKNILPLNSAMQVIQM
AQSVGSAVNAASANQNVIILQPPSTTPCPTVMRAEVPNQTVGQQIVIIQAA-NQNPLPLL
SAPPSGSVRLPVNGANAIIGSNNSVQNVSTPQTFGGKHLVHILPRPSSLS-TSNSTQTFS
VTMSNQQQPQTISLNGQLFALQPVMSSSGTTNQTPMQIIQPTTSEDPNTNVALNTFGALA
SLNQSISQMAGQSCVQLSISQPANPQTATNSQTTPANCVSLTTTIAPSTTTDNSATLPNT
YNFVTTSSVNTVACLPPTMKSKRLNKKPGAKKHLAA-SKPACILNPVK-VGKLDCPRTEG
SAESPCN-DGLLESLPIVLP-SVAVSEAN--------NV------SVSASHSLDILNSES
-------------VMPESVSKSKSAE--VSPCQESVTSEHSAAAPEKSKDSMPILQQETS
QDKPPTSLALSDATKSCTSANVLIPSPSDPQVLASQVSGLSSTTSTASTDYVSEVEIVAE
PCRVDQDS-SDTIQATGLLKGQGLTTLLSDLAKEKDPQ--KSSLSVQIDHPDFSSENSK-
VVNSSVDLHP-KQELLLMNSEDS----------------------PPQADSPMSTSSGSS
RSFSVASMLPETTREDVTSS-T-TNTCDSCTFVEQTDIVALAARAIFDQENIEKERVGIQ
--ADIREVTSKSSEASSLE--GDQPFKSH-PKENGTRQAETTPNEFNSQDSI---EITVD
--RPLEKPSCSLG-IKTSNASLQASTSQPPTLTSLS-------SSITHPLVSCAGLSQTS
DQTAVPTTVNLTVSSSSYGSQPPG-PSLMTEYSQEQLNTMAST-IPNSQIQEPL-LKPNH
ENRKDSAKRAIQDDLLLSSAKRQKHCQPVPLRLENMSLMSRTPDNISDQAQMMVSQIPPN
SSNSVVP--VSNPAHGDGLTRLFPAGNNFVAPALRQTEVQRSSQPSV-AEQ--QQTPASQ
HLQALQQH--VPPQGVSHLHSNHLYIKQQQQQ-----------------QQAGQLRERHH
LYQL-QHHVPHGENAVHSQPHNVHQQRTLQQEVQMQKKRNLVQGTQGSQLSLQPKHHATD
QSRPKSGQPHPHHQQMQQQMQQHFGSSQPEKSCENPSASRNHH-SHPQNHLNQDIMHQQ-
QDVG------RVTSEHVSGHNPMQRLLTSRGLEQ-QMVSQPSIVTRSSDMTCAPHRTERN
RVSSYSAEALIGKTSSNSEQRMGILIQGSRVSDQLEMRSYLDVPRNKSLAIHNMQSHV--
DHTVASD-IRLSDCQTFKPSGASQQPQSNFEVQSSRNNEIGNS-VSSLRSMQSQAFRISQ
N-GPPAIDRQKRLPYPPVQGIPAGNAIPP-RDSENTCHQSFMQSLLAPHLGDQVIGSQRS
LSEHQRNTQCGPSSAIEYNCPPTHESVHIRRDSESQNRESCDMSLGAINTRNSTLNIPFS
SSSSSGDIQGRNTSPNVSVQKSNPMRITDSHGTKGHMNPPVTTNMHGVARPALPHPSVSH
GNADQGP-PVRQANTSVSQRSRHPLQDS-GSSKIRQPERNRSGNQRHSNVFDPSLPHLPL
STSGSMILGRQQPATEKRGSIVRFMPDSPQVPNDNSGPDQHSLSQNFGFPFIPEGGMNPP
INANTSFIPQVTQPSATRAPALIPVDPQNTLPSFYPPYSPAHPTLSNDISIPYFSNQMFS
NPTTEKVNSGSLNNRFGSILSPPRPVGFAQPSFPLLPDMPPMHMTN-SHLSNFNMTSLFP
EIATAL-PDGSAMSPLLTIANSSASDSSKQSSNRPAHNISHILGHDCSSAV

Query Results

"ENSGT00390000015759_0"

ENSGT00390000015759_0