ENSGT00390000015123_0 : Linker Region Query Results

--MSRAVNLTVPCPVQLGSLRNDSLEAQLHEYVKQGNYVKVKKILKKGIYVDAVNSLGQT
SLFVAALLGLTKLVDLLVDYGSDPNHRCFDGSTPVHAAAFSGNQWILSKLLDAGGDLRLH
D KKGQNPQTWALAAGKERSTPM--VEFMQ-RCTLHMQAIL-QGFS-YDLLKKIDSPQRLI
SSLPRFGGFMQGSP---SSSPVRT--LKAGVISAQNIYSFGFGK----------------
-------------------------------GLCLQFYLTGG-TQLAYLGSLPVIGEKEV
IQADDEPTFSFFSGP YMVMTNLVWNGSRVTVKDLRLP-SHPHCSRLWLADLLIAEQEHSS
KLRHPHLLQLMAVCLSQDLERTRLVYERITVGTLFGVLHERRCQFPVLHMELIVHLLLQV
SDALRYLHSRGFIHRALSSYAVHIVSTGEARLTNLEYMMES-QDGGV--HRDLTHIPLPT
QLYNWAAPEVILQKTASVKSDIFSFSMIIQEILT--DNIPWNDLDGADIKEAIVLGNYLE
ADVRLPKPYYD-IVKSGIQVKQRDRAMNLQDIQYILKNDLKVTSEDFIGGQRTQPTESSR
VRRYEVHPDTNVCLGLTSEYLKETSDLEIKEL----------KEM-GSQLPSPKSHSSPT
EK--VTPDPQVPDPSLMTKETKHQDT--------------VYFDCSVA-GESRSP---SP
GRASLCSFEMNEINSG-CLSVQEDREEESPAADSFCEGAGQN-QVDE-LKSLEEE-----
-LEKIE-REACCSY-EDE-----SSSETEVEFSFDDCDWQSDSLNSSSLVEPPREAKSNV
NSRSKTE-EYISKCVLNLKISQTIAHQNAELVRSIQQKLDEVEMMQKEQE--EKMSSWIS
-------L------REYLK--T---LPPARGPPTLNYIPPVLQLS------DIGSNCPIL
METPR-------------------------------------------------RPSILC
ALGKQSKVEQFQSFQGAKDNLGRS-RNQTLNSQGRP-RESGARPKVTQ-LNSA--LLTMP
SRPQGPPVSSRLGQGFTR---IGMESVSSELCNAKSR--------NQEDDGEVYLKWKME
VKEMAEKAAAGQLVAPPWHPQISLNLEIEN----ENDPDPLPQLP--------------V
RDPEIADCQ---------PAFECPRKSG----N--GKYNKTDSSDPNSNWHG-RRPGPGN
LAXXXXXXXX------------XXXXXXXXXX------XXXXXXXXXXXXXX----XXXX
XXXXXXXXXXXX---XXXXXXXXPEHEYFYSSTAQQNMALETSS--PI-EESFKGTQDAA
AQ------TQASG-EKRFPVRKSV-EKNTEIWIKSQFQ-IRSTEGE----QEDTLKES--
-PKEPKEKDITLTDIQDLSSINCEQDGSFKETSCKTPKINHAPTSVSTPVSP---ESISS
TTSQYKDCLENITFP-VKTGPTSVLNSQESIQASSDKSATVR-EKAKSLDSLLSSSKAPP
SRVADL--KKLFAFSGVGSPSIVKAPE-T-------------S-HTIQRRSLP--KVEAI
SQHHVDDLPPPSQELLDEIEHLKQQESSSPEQE-EK----AARAPAG-S--AADQRHLGT
----EEPSSNKEDSSVLWTKESQNLEEDTERAHSTLDEDLERWLQPPED-SGELEDLRK-
RSAE-ETRIKNQEVGEEKKKGEASITSET-RSESFL-GTP-------EK-DELKPCFWKR
LGWSE------P----------------SRIIVLDQSDLSD-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---

--MSRAIHFPVPCPVQLGTLTDDSLEAQLLEYATQGNYVKVKKILKKGICVDAINSLGQS
ALFVAALLGHMKLVDVLVDYGSDPNHRCFDGSTPVHAAAFSGNQWILSKLLNAGGDL RLH
DEKGRNPQAWALAAGKDRSTQM--VEFIQ-RCTSHMKAII-QGFS-YDLLKKIDSPQRLI
CSPPWFGSLIQGSP---NNSPNRQ--IKPGIISAQNIYSFGFGK----------------
------------------------------------FYLTPG-MQLTYPGSLPVIGEKEV
IQADDEPTFSFFSGPYMVMTNLVWNRSRVTVKELNLP-TRPHCSRLRL ADLLIAEQEHSS
NLRHPNLLQLMAVCLSRDLKKIRLVYERITVGTLFSVLHERRSQFPVLHMEVIVHLLLQI
ADALIYLHSRGFVHRSLSSYAVHIVSAGEARLTNLEYMMEN-QDNGV--HRDMTRVPLPT
QLYNWAAPEVILQKAATVKSDIYSFSMIIQEILT--DNIPWNGLDGSVIKETIALGSYLE
ADVRLPEPYYD-IVKSGIHAKQKNRTMNLQDIRYILKNDLK----EFLGAQKSQPAESPR
MQSYEAHPDVNPCLGLTSEYQKDAPDLDIKEL----------KEM-GSQPHSPTDHSIPT
GK--TTLTPQVLDSSLSAQEPENLKV--------------P-PPASCLAEEVRSP---TT
SQASLCSFEINEIYSG-CLYLGTDIEEECPETASLPEGDKLN-QVDE-LPSLEEE-----
-LDKME-RELHCFCEEDK-----SFSEVDTDLSIEDGDWQSDSISSLSLSEPTREDKGKM
NSWSKTD-EYVSKCVLNLKISQVMMQQNSEWLRKLEQEIDELELAQKELDN-QCRSLWDA
-------S------LRFANAK----FLFAVGPPSLTYLPPVMQLSEPRHS-ENGDFWLAL
ARSPGTERDFQE----GHVGKY-PKKLSDCGWKPF---IQVSEESSRDQSETNNQLPIVC
GPGKQNTGEQLPSIQEAKESLERN-RSQNT------------------------------
-------------------RRINVGSVSSEIYNIKSR--------NNEDDGETHLKWKMA
VKEMAEKAVSGQLLVPSWNPQSSLPFESKV----ENKATALPQPP--------------V
RGPESTYWQ---------HIVEYRRENDELKGN--TKFGKMENSDCDKNKHS-RQTGLRS
FTSIRYPFFR------------KHEQPERSEA------SHASCDTSVGTEKF----YST-
------------------------------------------SS--PI-EEDFERIHSSL
AE------PQGYV-EGEFQMSEIF-GKNAEILTEPLFQTIQCAEDE----QREAPEET--
-LKEPKQKDISLTDIQDLSSISYEKDGYFKESSCKTPKLKHAPTSVSTPLSP---ESISS
AASHYEDCLENTTFQ-VKKGSSFCWNGQESMRTLSAKFTTVR-ERAKSLESLLASSRPLP
AKLTDP--KKWSTYSGVGSSNISTASV-T-------------SANATQRKSLPRELVEAT
SQHLIDELPPPAQELLDEIEHLKQQQILPMVSHE-N----TAHDLST-T--ENDKKHLEE
----PETNSSKD-SSFLSTKEIQDLE-DTERAHSSLDEDLERLLQSPEE-NMALLDPSK-
GSTR-EKKPKDQDAVEQKRKRKESTKPERRKSDSFL-GTL-------ED-DELKPCFWKR
LGWSE------P----------------SRIIVLDQSDLSE-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---

--MSRAVQLPVPCPVRLGSLKGDSLEAQLHEYVREGSYLKVKKILKKGIYVDAVN S LGQT
PLFLASLLGLTKLVDILVDYGSDPNHRCFDGSTPVHAAAFSGNQWILSKVLDAGGDLRLH
DEKGQSPQAWALTAGKECSTMM--VEFMH-RCASHMQAVV-QDFS-CDLLKKVDSTERLI
CSLPRFGGLMQGSP---NGPSKRP--RKTGVISAQNIHSFGFGK----------------
------------------------------ELPFKQFCLSAR-TRVTYLGSLPIIGEKEI
IQADDEPAFSFCSGPYMVMTNLVWKGSRVTVKELHLP-THPHCSKLRLADLLIAEQEHSS
KLRHRHLLQLMAVCLSQDLEKTRLVYERITIGTLFSVLHERRSEFPLLHMEEIVHLLLQI
SDALRYLHSWGFIHRALSSYAIHIISTWEARLTNLEYMLES-QDRDV--HRDLTRVPLPA
QLYRWAAPEVILQKEVTVKSDVYSFSVIIQEILT--DNIPWDGLDGSVIKRAIVVGNYLE
ADFRLPKPYYD-IVKSGIQVRQKDRTLNLQDIQYILKNDLK----ELIGAQRTQPTESPR
VQRYERHPDVGVYLGLTSEHLKENPDLEIKEL----------KEA-GIQLHSSRNPSE--
--K-ATPDPQVPDPSLMAKEAQRQDA--------------APPACFV----ARSP---SS
ELSSLCSFEMNEIYSR-CLDTEGDKEKEPPGVGLSLEGASQN-QGGE-LASLEEE-----
-LEKME-REACCFCEKSE-----SSSEADTEVSFEDWDQQNGSLSSPSPPKPAREAKCKV
SKWSKTD-MYISKCILDVKIAQAMANQNNEK---IKQKFNEYERRLKEQE--ECMSLWAS
-------S------RMFPNLSH---LPAAVGPPSSVYIPPVLP---SQRP-DAGGNCPTL
ARSPR-------------------------------------------------TLLTLC
GPGEQSPGEQFPPTQGARDSPEGN-RNQNTCSQGQP-GESSAQAKVAQ-LNSS--LFTMS
NHPKGPPVTATPVQGSAR---INMESVSSEIYNTKSR--------NN-DVGKGHLKWKME
VKKMAEKAAAGQLAVPPWHPQSGSTLENEAEA--ENEPDPLLQPP--------------I
RDAENVTWR---------RVVEYSRESA-PGGT--GKRDKTDSGDHEDDQRG-RQPG--S
FPSVSHPSPR------------KSEEPEHSEV------FQARSEASVVTEKS----CNDQ
SWPSIGSPESSE---DIRNEFLTPDNEYSYSPTAQENLALETSS--PI-EEDFEGMQEAF
AR------CPVSG-EGKVQTRQSF-GKDAEVLTRSQFQPIQSPEGE----QEETLKES--
-PKELKEKDISLTDIQDLSSISYEQDASFKEVSCKTPRINHALPSVSTPLSP---ESISS
SDSHYKDCLESFTFQ-DKTGSTSCWSYQES--TLSDKFTTVQ-EKVKSLESLFASSETLP
SRLTDH--KRSSTFTRTGSSRSAKVPD-K-------------SSLAIQKRSLPRELIEAI
SQHHIDKLPPPSQELLDEIEHLKRQQASSAVLGEDP-----ANPLGV-T--AKDQSHLEE
----QETSSTKEDSSVLWTQETQGLEEDTERAHSSLDEDLERWLQPPED-ITVLQDLPK-
GSAR-ETDTKDQEVGEKKRKVEEGMKPER-TSESFL-GAS-------KE-EELKSCFGKR
LSWSE------P------------SRNTHRIIVLDQSDLSD-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---

--MSRAVPLPVPCPVQLGSLRNDSLEAQLHEYVKQGNYVKVKKILKKGIYVDAVNSLGQT
ALFVAALLGLTKLVDVLVDYGSDPNHRCFDGSTPVHAAAFSGNQWILSKLLDAGGDLRLH
DEKGRNPKTWALTAGKERSTVM--VEFMQ-RCASHMQAII-QGFS-QDLLKKIDSPQRLI
CGLPRFGGLMQGSP---NGSPNRL--LKAGVVSAQNIYSFGFGKVR--------------
------------------------------AVFCFQFYITGG-TQLAYLGSLPVIGEKEV
IQADDEPTFSFFSGPYMVMINLVWNGSRVTVKELNLP-THPHCSRLRLADLLIAEQEHSS
KLRHPHLLQLMAVCLSQDLEKTRLVYERITVGTLFSVLHERRSQFPVLHMEVIVHLLLQI
SDALRYLHSRGFIHRSLSSYAVHIVSTGEARLTNLEYMMES-QDGGV--HRDLTRVPLPT
QLYNWAAPEVILQKAATVKSDIYSFSVIIQEILT--DNIPWNGLDGSVIKDAIVLGKYLE
ADVRLPKPYYD-IVKSGIQVKQKDRTMNLQDIRYILKNDLK----DFIGAQRTQPTVSPR
VQRYELHPDVNVYLGLTSEHPKETSDLEIKEL----------KEM-GMALTHRMILQALV
TF--GALSHVAPEGERMAQKDWAG------FC--------SAPSGLVV-NFAHSA---SV
AQGSLVQISAADLHTA-HQAMLWHQLHSPRGRSSPTEKAAPDPQVPD-SSLMAKE-----
-TQNQE-TA-SPACSVDE-----SSSEADTELSFEDLDWQNGSLSSLSLPEPAREAEGNV
SNRSMTE-EYISKCVLNLKISQMLMHQNADLLRNTQQKIDKLEMIQKEQE--ERKSLWAS
-------S------REFANVCD---LPSALGPPALSYVPPVMQLSGGQQP-DTGGNCLTL
ARSSR-------------------------------------------------TLPTLC
GPGKQSRSEQVQPPQGAKDSLERN-RNQNINSQGRP-SEASAQAKVSQ-LSSV--LFTTS
SRQQGPPMSSSPGQGSAI---SM-ESVSSEICNAKSR--------NNEDSGEVHLKWKTE
VKEIAEKAATGQLAVPPWHPRSGLTLENEA----GNEPDPLLQPP--------------I
MEPENVDWQ---------QVAEYPRKNDEPGGS--VKFDKTGHSDHDSDQHG-RQSGPRS
FTGIRHPSLR------------KNEQPEHSEV------FQASSDASVVIEKS----YSDQ
SVQSTCSPESSE---DITDEFLTPEYDYFYSSAAQENLALETSS--PI-EEGFEGIQDAF
AQ------PQASG-EEKFQVRKSL-GKNAEVLTKSHFQPVRSTAGE----QEETLKES--
-PVEVKEKDISLTDIQDLSSISYEQDGSFKEVSCKTPRINHAPTSVSTPLSP---GSISS
AASRYKDCLESITFQ-VKTGSTSCWNSQESIPTLCDTFTTVR-ERAKSLDSLLTSSETLR
SRLTDL--KKLSTFTGAGSSSIAKAPD-T-------------SSHAMQRRSLP--KVETI
SQHNIDELPPPSQELLDEIEHLKQQQASSTVLD-ES----TASHLGI-T--ANDQRHLEE
----QETISKKE-DNMLWTKETQDLEEDTERAHSTLDEDLERWLQQPED-SMELQDLPK-
GSAR-EMNTKDQEVGKKKRKGEESTKPERRKSESFL-GTS-------EE-EELKPCIWKR
LGWSE------P----------------SRIIVLDQSDSSD-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---

--MSRAVHLPVPCPVQLGSLRNDSLEAQLHEYVKQGNYVKVKKILKKGIYVDAVNSLGQT
ALFTAALLGLPKLVDVLVDYGSDPNHRCFDGSTPVHAAAFSGNQWILSKLLDAGGDL RLH
DEKGRNPQTWALAAGKEHSTAV--VEFMQ-RCAGHMQALI-QGFS-HDLLKKVDSPQRLI
CGLPRFGGLMQGNP---NGSPNRM--IKAGVVSAQNIYSFGFGKVR--------------
------------------------------VVLCFQFYLTGG-TQLAYLGSLPVIGEKEV
IQADDEPTFSFFSGPYMVMTNLVWNGSRVTVKELQLP-SRLPCSRLRLADL VIAEQEHSS
KLRHPHLLQLMAVCLSPDLEKTRLVYERITIGTLFGVLHERRSQFPVLHMEVIVHLLLQV
SDALRYLHSRGFIHRSLSSYAIHIVSTGEVRLTNLEYMVES-QDRGV--HRDLTRIPLPT
QLYNWAAPEVILQKAATVKSDIYSFSVIIQEILT--DSIPWDGLDGSVIKETIVLGSCLE
ADVRLPKPYYD-IVKSGIQVKQKDRTMNLQDIQYILKNDLK----VSSPGVRTQPAESPG
AQRYELHPDVSVYLGLTAEHPKETPDLEIKEL----------KET-GNQLHSPRSHSSPT
KK--ATPEPQVPDPGPVALGTQNQDA--------------ASPACPAM-EESRSP---SP
DQMSLCSFEINEIYSG-CLDTDEDKEEEPPGASSSPEGSRPK-QIDE-LKSLEEE-----
-LEKME-SEACCFCDEDE-----NSSEADAELCFEDWDGQKGSLYLPSLPEPARGTKGNA
SSRSMTE-EHISKCVLNLKISQTLMHQNADLLGKIQQKLGKIEVIQKEQE--ERWSLWA-
-------S------REFVNVHD---LPLAVGPPASSYVPPLVQLPGGQQP-DTGGSCPTR
ARSPR-------------------------------------------------TLLTLC
GPGTQSTGEQFQPTHGAKDGLERN-GSQNTS---RP-RESSAQTKLTG-PGRV--HLTLP
SRAQGPPASASPGQGSIR---ISMESVSSGIHNANSR--------NNEDDGEIHLKWKTE
VKDMAEKAATGQLAVPPWHHHSTDTLENEP----EDEPNPLLQPP--------------T
RVLEHVGWW---------RAVEYPKKNDEPGGN--GKCDKTDNRDHSSDQHG-RQPGPPS
FASISHLLSG------------RNELPEHSEV------FQANTEASVVVETS----YSDH
SVQSTCSSESSE---EITDEFLTPDHEYFYSPTAQELLTLETSG--PI-DDDLEEVQDTR
AQ------PPASD-EEMFQMRRSL-GKNAEILTRSQFQPIQSTEDK----QEETLKES--
-PKEMKEKDISLTDIQDLSSISCEQDGSFKEATCKTPKTNHAPTSVSTPLSP---GSISS
AASQYKDCLESITFQ-VKTGSTSCWNSQESIETLPDKFTTVQ-EKAKSLDSLLTSPEALL
SRQTNL--KRLPAFTGAGSSSVAKVPD-T-------------SSHATQRRSLP--KVEAI
SQHHIDELPPPSQELLDEIELLKQQQASSTVMD-EN----TAHHPGI-T--ANDQRHLEE
----QETNSKKEDSSMLWTKETQHLEEDTERAHSTLDEDLERWLQPPEDARSHRI-SPR-
AQ-----------------QGSS---------------------------SPSGVIFFTR
F-----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---

--MSRAVPLPLPCPVQLGTLRNDSLEAQLHEYVKQGNYLKVKKILKKGIYVDAVNNLGQT
ALFVAALLGLRKLVDVLVDYGSDPNHRCFDGSTPVHAAAFSGNQWILSKLLDAGGDL RLH
DERGQNPKTWALTAGKERSTQ--IVEFMQ-RCALHMQAII-QGFS-YDLLKKIDSPQRLV
YSPPWFGSLVQGNP---NGSPNRL--LKAGVISAQNIYSFGFGK----------------
------------------------------AMPWFQFYLTGA-TQIAYLGSLLVIGEKEV
IQADDEPTFSFFSGPYMVMTNLVWNGSRVTVKELNLP-THPHCSKLRL ADLLIAEQEHSS
KLRHPYLLQLMAVCLSQDLEKTRLVYERITIGTLFSVLHERRSQFPVLHMEVIVHLLLQI
SDALRYLHSQGFIHRSLSSYAVHIVSPGEARLTNLEYMLES-KDRGE--QRDLTRVPLPT
QLYNWAAPEVILQKAATVKSDIYSFSMIIQEILT--DDIPWNGLDGSVIKEAIVLGNYLE
ADVRLPKPYYD-IVKLGIHIKQKDRTMNLQDIRYILKNDL----KDFTGTQRTQPTESPR
VQRYGLHPDVNVYLGLTSEHTRETPDMEIIEL----------KEM-GSQPHSPRVHSL-F
TEG--TLDPQAPDPCLMARETQNQDA--------------PCPT-PFMAEEASSP---ST
GQASLCSFEINEIYSG-CLTLEDDI-EEPPGAASSLEADGPN-QVDE-LQSMEEE-----
-LDKME-REACCFCSEDE-----SSSKAETEYSFEDWDWQNGSLSSLSLPESTREAKSNL
NNRSMAEEYLISKCVLDLKIMQTIMHENDDRLRNIEQILDEVEMKQKEQEE--HMSLWAT
-------S------REFTDVYN---LPPAVGPPSLNYIPPVLQLSGGQQP-DTSGKCPTL
PRFPRM-------------------------------------------------LLTLC
DPGKQNTDEQFQGTQGVKDSLERS-RIQNTSSRGKP-RESTAQAKATQ-FDSA--LFTLS
SHWQGPSASPNSHWDSTR---MSVDPVSSEIYNAESR--------N-KDDGEVHLKWKME
VKEMAEKAATGQLTVPPWHPQSSLTLESEA----ENEPDALLQPP--------------I
GSPENTDWQ---------RVIEYHRENDEPRGNA--KFDNTGNNDCDSDQHD-RQPRPGS
FTNIRHPSPR------------QKEQPEYSEA------FQASSDALVAVEKS----YSHQ
SMQSTCSPESSE---DITDEFLTPDDEYFYSSTAQENLALETSS--PI-EEEFEGIQGAF
AQ------PQVSG-EEKFQMRKIL-GKNAEILPRSQFQPIRSTEDE----QEETSKES--
-LKELKEKDISLTDIQDLSSISYEPDSSFKEASCKTPRINHAPTSVSTPLSP---GSVSS
AASQYKDCIESITFQ-VKTESASCWNSQEFIQTLSDEFISVR-ERAKKLDSLLTASETCP
SRLPGL--KRLSSFIGAGSSSLVKACDSS-------------PPHATQRRSLPK--VEAF
SQHHIDELPPPSQELLDEIELLKQQQGSSTVLHE-----NTASDAGG-T--ANDQRHLEE
----QETDSKKEDSSMLLSKETGDLGEDTERAHSTLDEDLERWLQPPEE-SMELQDLPK-
GSER-EINIKDQEVGEDKRKREDSITPERRKSESVL-GTS-------EE-DELKPCFWKR
LGWSE------S----------------SRIIVLDQSDLSD-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---

--MSRAVPLPLPCPVQVGTLRNDSLEAQLHEYVKQGNSLKVKKILKKGIYVDAVNNLGQT
ALFVAALLGLRKLVDVLVDYGSDPNHRCFDGSTPVHAAAFSGNQWILSKLLDAGGDL RLH
DERGQNPKSWALTAGKEHSTQ--IVEFMQ-RCASHMQAII-QGFS-YDLLKKIDSPQRLV
YSPPWFGGLVQGNP---NGSPNRL--LKAGVISAQNIYSFGFGK----------------
------------------------------AMPWFQFYLTGA-TQIAYLGSLLVIGEKEV
IQADDEPTFSFFSGPYMVMTNLVWNGSRVTVKELNLP-THPHCSKLRLADLLIAEQEHS-
-----------------------------------------R SQFPVLHMEVIVHLLLQI
SDALRYLHFQGFIHRSLSSYAVHIVSPGEARLTNLEYMLES-KDRGE--QRDLTRVPLPT
QLYNWAAPEVILQKAATVKSDIYSFSMIMQEILT--DDIPWNGLDGSVIKEAIVLGNYLE
ADVRLPKPYYD-IVKSGIHVKQKDRTMNLQDIRYILKNDL----KDFTGTQRTQPTESPR
VQRYGLHPDVNVYLGLTSEHTRETPDMEIIEL----------KEM-GSQPHSPRVHSL-F
TEG--TLDPQAPDPCLMARETQNQDA--------------PCPA-PFMAEEASSP---ST
GQASLCSFEINEIYSG-CLTLEDDV-EEPPGAASSLEADGPN-QVDE-LQSMEDE-----
-LDKME-REACCFCSEDE-----SSSKAETEYSFEDWDWQNGSLSSLSLPKSTREAKSNL
NNRSMTEEYLISKCVLDLKIMQTIMHENDDRLRNIEQLLDEVEMKQKEQEE--RMSLWAT
-------S------REFTDVYN---LPPAVGPPSVNYIPPVLQLSGGQQP-DTSGKCPTL
PRFPRM-------------------------------------------------LPTLC
DPGKQNADDQFQGTQGVKNSLEGS-RIQNT------------------------------
----------------RR---MSVDPVSSEIYNAESR--------N-KVDGEVHLKWKME
VKEMAEKAATGQLTVPPWHPQSSLTLESEA----ENEPDALLQPP--------------I
GSPENTDWQ---------QVIEYHRENDEPRGNA--KFDNMGNNDCDSDQHD-RQPRPGS
FTSIRHPSPR------------QKEQPEYSEA------FQASSDALVAVEKS----YSHQ
SMQSTCSPESSE---DITNEFLTPDDEYFYSSTAQENLALETSS--PI-EEDFEGIQGAF
VQ------PQVSG-EEKFQMRKIL-GKNAEILPRSQFQPIRR------------------
----------SLTDIQDLSSISYEPDSSFKEASCKTPKINHAPTSVSTPLSP---GSVSS
AASQYKDCIENITFQ-VKTESASCWNSQEFIQTLSDEFISVR-ERVNKLDSLLTASETCP
SRLPGF--KRLSSFIGTGSSSLVKACDSS-------------PPHATQRRSLPK--VEAF
SQHHIDELPPPSQELLDEIELLKQQQGSSTVLHE-----NTASDAGG-T--ANDQRHLEE
----QETDSKKEDSSMLLSKETGDLGEDTERAHSTLDEDLERWLQPPEE-TMELQDLPK-
GSER-ETNIKDQEVGEDKRKREDSIKPERRKSESVL-GTS-------EE-DELKPCFWKR
LGWSE------T----------------SRIIVLDQSDLSD-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---

--MSRAVPLPLPCPVQLGTLRNDSLETQLHEYVKQGNYLKVKKILKKGIYVDAVNNLGQT
ALFVAALLGLRKLVDVLVDYGSDPNHRCFDGSTPVHAAAFSGNQWILSKLLDAGGDL RLH
DERGQNPKTWALTAGKERSTQ--IVEFMQ-RCALHMQAII-QGFS-YDLLKKIDSPQRLV
YSPPWFGSLVQGNP---NGSPNRL--LKAGVISAQNIYSFGFGK----------------
------------------------------AMPWFQFYLTGA-TQIAYLGSLLVIGEKEV
IQADDEPTFSFFSGPYMVMTNLVWNGSRVTVKELNLP-THPHCSKLRL ADLLIAEQEHSS
KLRHPYLLQLMAVCLSQDLEKTRLVYERITIGTLFSVLHERRSQFPVLHMEVIVHLLLQI
SDALRYLHSQGFIHRSLSSYAVHIVSPGEARLTNLEYMLES-KDRGE--QRDLTRVPLPT
QLYNWAAPEVILQKAATVKSDIYSFSMIIQEILT--DDIPWNGLDGSVIKEAIVLGNYLE
ADVRLPKPYYD-IVKLGIHIKQKDRTMNLQDIRYILKNDL----KDFTGTQRTQPTKSPR
VQRYGLHPDVNVYLGLTSEHTRETPDMEIIEL----------KEM-GSQPHSPRVHSL-F
TEG--TLDPQAPDPCLMARETQNQDA--------------PCPT-PFMAEEASSP---ST
GQASLCSFEINEIYSG-CLTLEDDI-EEPPGAASSLEADGPN-QVDE-LQSMEEE-----
-LDKME-REACCFCSEDE-----SSSKAETEYSFEDWDWQNGSLSSLSLPESTREAKSNL
NNRSMAEEYLISKCVLDLKIMQTIMHENDDRLRNIEQILDEVEMKQKEQEE--RMSLWAT
-------S------REFTDVYD---LPPAVGPPSLNYIPPVLQLSGGQQP-DTSGKCPTL
PRFPRM-------------------------------------------------LPTIC
DPGKQNTDEQFQGTQGVKDSLGRS-RIQNTSSRGKP-RESTAQTKATQ-FDSA--LFTLS
SHWQGPSASPNSHWDSTR---MSVDPVSSEIYNAESR--------N-KDDGEVHLKWKME
VKEMAEKAATGQLTVPPWHPQSSLTLESEA----ENEPDALLQPP--------------I
GSPENTDWQ---------QVIEYHRENDEPRGNA--KFDNTGNNDCDGDQHD-RQPRPGS
FTSIRHPSPR------------QKEQPEYSEA------FQASSDALVAVEKS----YSHQ
SMQSTCSPESSE---DITDEFLTPDDEYFYSSTAQENLALETSS--PI-EEDFEGIQGAF
AQ------PQVSG-EEKFQMRKIL-GKNAEILPRSQFQPIRSTEDE----QEETSKES--
-LKELKEKDISLTDIQDLSSISYEPDSSFKEASCKTPKINHAPTSVSTPLSP---GSVSS
AASQYKDCIESITFQ-VKTESASCWNSQEFIQTLSDEFISVR-ERAKKLDSLLTASETCP
SRLPGL--KRLSSFIGAGSSSLVKACDSS-------------PPHATQRRSLPK--VEAF
SQHHIDELPPPSQELLDEIELLKQQQGSSTVLHE-----NTASDAGG-T--ANDQRHLEE
----QETDSKKEDSSMLLSKETGDLGEDTERAHSTLDEDLERWLQPPEE-SMELQDLPK-
GSER-EINIKDQEVGEDKRKREDSITPERRKSESVL-GTS-------EE-DELKPCFWKR
LGWSE------S----------------SRIIVLDQSDLSD-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---

--MSRPVHLPVPCPVQLGSFRNDSADAQLHEYVKQGNCVKVKKMLKKXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXRCFDGSTPVHAAAFSAHQWVLSRLLDAGGDLRLH
DEKGRSPQAWALAAGKDRSSAV--VDFMQ-RCATHMQAVL-QGF--CDLLRKIDSPQRLV
CGLPRFGGLRQGXXXXXXXXXXXX-----XXXXXX-------------------------
----------------------XXXXXXXXXARGFQFYLTGG-KQLAYLGALPVVGAKDV
IQADDEPTFSFLSGPYMVMTXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXX
KLRHPHLLQLMAVCLSQDLETTHLVYERITVGTLFSVLHERRSQFSVLHMEVIVHLLLQI
SDVLRYLHTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXHEGGV--HKDLTGVPLPT
QLYNWAAPEVVFEKTATAKSDIYSFSVVIQEIL T--DTVPWNGLEGSVIKETMALGNHLE
ADVRLPKPYYD-IVKSGIQVKQKDRTMTLQDIRYILKNDLKV--SDFLGAQRTQPMESPR
ARSYGPHPDVNVYLGLTSEHPREPPDLXXXXX----------XXX-XS QLRSPRHSMA--
----EALDAQAREPSLGAKETPSQGAAS--------------PRPPPVEEETGSS---SA
DPGSLSSFEINEICSG-CLAVGSGKGEEPLGSLSSLEVDSST-QEDE-LKSMEEE-----
-LDRME-REAGCFSDEDG-----SSLDVETEFSSEDWAWEQDSPSSHKAREPTREARGNV
SSRSMTE-EYISKCVLNLKIAQTLVHQSADLLSTTQQKIDQLEGMQREQE--ECRSLWES
-------S------REFANVPD---APSALGPPALGYIPPVGPLSGDQQL-DSRDNSRTL
PRSPR-------------------------------------------------PLPAPR
ASGKCDATGQFEPSQGAQDSLDRS-RSPDPNSHRRP-RESSSRAGVTQ-IHSA--LLETP
SHPQGHPGSLPPARDSAR---ISVESVPSEVYNPKSR--------NR-EDEEVHLKWKME
VKEMAEKACAGRLMVLSXXXXXXXXXXXXXXXXXXXXXXXXXXXX--------------X
XXXXXXXXX---------XXXXXXXXXXXXXXX----XXXXXX--XXXXXXX-XXXXXXX
XXXXXXXXXX------------XXXXXXXXXX------XXXXXXXXXXXXXX----XXDQ
SAGSSDSPASSE---DLTDEFLTPDYEYFCSSTAQETLALEXXX--XXXXXXXXXXXXXX
X--------XXXX-XEKLHVVRSL----KNEESQSQFRPI-SAEGE----QEDTSKEP--
-PKDRKDKDISLSDIQDLSSISNERDGSFKEASCKTPKTRHAPTSVSTPLSP---GSVSS
SASRYKDCHGSFAPE-IQRGSASCLSSPESTPTSLDKIITVR-ERARSLDSLLTSSDL--
--------KKWSTFPSPGSHRITQASS-T-------------SPATSQRRSLP--KVEAI
SQHHIEELPPPSQELLEEIEHLKQQQPAATMPAEDT-----ASEGGR-S--ANDQRHLAE
----QEPDSKRGDGSKLWSKQTEDPEDTD-------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---

--MSRAVHLPVPCPVQLGSLRNDSLEAQLHEYVKQGNYVKVKKILKKGIYVDAVNSLGQT
ALFIAALLGLTKLVDVLVDYGADPNHRCFDGSTPVHAAAFSGNQWILSKLLDAGGDL RLH
DEKGRNPQTWALASGKERSTVM--VEFMQ-RCAAHMQAVI-QGFS--DLLKKIDSPQRLI
SGVPRFGGLMPGNP---NGSPNRL--LKAGVISAQNIYSFGFGK----------------
------------------------------------FYLTGG-TQLAYLGSLPVIGEKEV
IQADDEPTFSFFSGPYMVMTNLVWNGSRVTVKELHLS-THPHCSRLRL ADLLIAEQEHSS
KLRHPHLLQLMAVCLSPDLEKTRLVYERVTVGTLFSVLHERRAQFPVLHMEVIVHLLLQI
SDALRYLHSRGFIHRSLSSYAIHIVSTGEARLANLEYMMES-QDGGA--HRGLTRVPLPT
QLYNWAAPEVILQKAATVKSDVYSFSVIVQEILT--DNIPWDGLDGSVIKETIVLGNYLE
ADVRLPKPYYD-IVKSGIQVKQKDRTMNLQDIRYIMKNDLK----DFIGAQRTQPTESPR
VQRYEFHPDVSVCLGLTSEHPKETPNLEIKEL----------KET-GGQFHSPRGHSSPT
GK--ATPEPPVPDISPVAQQTHRQDA--------------ASPACSVA-EEARNP---SP
DQTSLCSFEINEIYSG-CLDTADDPEEEHPGTGSSLEGATPN-QTDE-LKSMEEE-----
-LEKME-REACCFCDEDE-----SSSDADTELSCEDWEWQNDALRSPSQPEPARGAQGAV
NNRSMTE-EYISKCVLSLKISQTLMHQNADLLRNVQQKIEKLEKIQKEQA--ERRSLWAS
-------S------REFAGIHD---SPSALGPPASSYLPPVVQRPGDQQP-DPGGSGLTL
ARSPR-------------------------------------------------TLPTLC
GPGKQSRGEQFQPTHRAKDSLERD-RNQNTSSQGRP-RESSPQSRPTQ-LSSV--LLTEP
SHPQGPPASSNPGQDSTR---ISMQSVSSEIYNAKSR--------NNKDDGERHLKWKME
VKEMAAKAATGQLTVPPWHPRSGVALDSEA----ENEPDPLPQLP--------------V
KVSEHVDWQ---------QAAEYLKKSDEPGGN--DECGQTDS----SDQHG-RQSGPQR
FTSIRHLPPR------------KDEQPEHGEV------FQANSDASVAVEKS----YSGQ
STQSTCSPESSEDTEDMTDEFLTPDHEYFYASIAQENLALETSS--PI-DEDFEGIQHAC
AR------PQASG-EEKFQMRKSL-GKNAETLTKSQFQPIRSPEGE----QDKTLKEP--
-PKEAKEKDISLTDIQDLSSISYEHDNSFKEVSCKTPKINHAPTSVSTPLSP---GSISS
VASQYKDCLGSIPFQDTKTGSASCWTSQESTQTLSDKFTSVR-EKAKSLDSLLTSSEIVP
ARLTNL--KRLPAFTGAGSSSITKAPD-T-------------SCRATQRRSLPKE---AI
SQHHIDELPPPSQELLDEIEHLKGQQVSSTALD-EN----TASRPGS-I--ANDQRHLEE
----QETHSSKEDSSMLWTKETQDLEEDTERAHSTLDEDLERWLQPPGD-STQLPDLPK-
GPAR-EASSKDQEVGEKKRKEEESTKPERRKSESFL-GTS-------EE-EELKPCFWKR
LGWSE------P----------------SR------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---

--MSRGAPFPVPCPVLLGTFTDDSLEAQLHEYAKQGNCVKLKKILKKGVCVDAVNTQGQS
ALFVAALLGHVKLVDVLVDYGSDPNHRCFDGSTPVHAAAFSGNQWILSKLLTAGGD LRLH
DEKGRNPQAWALTAGKDRSTQ--MVEFMQ-RCTSHMKAII-QGFS-YDLLKKIDSPQRLI
GSPPWFGSLIQGSP---NSSPNRQ--LKPGIISAQNIYSFGFGK----------------
------------------------------------FYLTSG-MQLTYPGSLPVIGEKEV
VQADDEPTFSFFSGPYMVMTNLVWNRSRVTVKELNLP-TRPHCSRLRL ADLLIAEQEHSS
NLRHPNLLQLMAVCLSRDLEKIRLVYERITVGTLFSVLHERRSQFPVLHMEVIVHLLLQV
ADALIYLHSRGFIHRSLSSYAVHIVSAGEARLTNLEYLTES-QDSGA--HRNVTRMPLPT
QLYNWAAPEVVLQKAATVKSDIYSFSVIIQEILT--DSIPWNGLDGSLVKETIALGNYLE
ADVRLPEPYYD-IVKSGIHAKQKNRTMNLQDIRYILKNDL----KEFIGAQKTQPTESPR
GQSYEPHPDVNICLGLTSEYQKDPPDLDIKEL----------KEM-GSQPHSPTDHSFLT
VKP--TLAPQTLDSSLSAQKPDNANV--------------PSPPAACLAEEVRSP---TA
SQDSLCSFEINEIYSG-CLTLGTDKEEECLGTAASPEGDRPN-QGDE-LPSLEEE-----
-LDKME-RELHCFCEEDK-----SISEVDTDLLFEDDDWQSDSLGSLNLPEPTREAKGKT
SSWSKTD-EYVSKCVLNLKISQVMMQQSAEWLRKLEQEVEELEWAQKELDS-QCSSLRDA
-------S------LKFANAKF---Q-PAVGPPSLAYLPPVMQLPGLKQP-ENGGTWLTL
ARSPGNEREFQE----GHFSKK-PEKLSACGWKPF---TQVSEESRGDCSELNNQLPTLR
GPGKQSTGEQLPSTQEARESLEKN-TNQNS------------------------------
---------------------RSMASVSSEIYATKSR--------NNEDNGEAHLKWRLA
VKEMAEKAVSGQLLLPPWNPQSSAPFESKV----ENESTPLPRPP--------------I
RGPESTEWQ---------HILEYQRENDEPKGNT--KFGKMDNSDCDKNKHS-RWTGLQR
FTGIRYPFFR------------NHEQPEQNEA------SQASCDTSV-------------
------------------------GTEKF----------YSTSS--PI-GDDFERFQDSF
AQ------RQGYV-EENFQIREIF-EKNAEILTKPQFQAIQCAEDK----QDETLGET--
-PKELKEKNTSLTDIQDLSSITYDQDGYFKETSYKTPKLKHAPTSASTPLSP---ESISS
AASHYEDCLENTTFH-VKRGSTFCWNGQEAMRTLSAKFTTVR-ERAKSLESLLASSKSLP
AKLTDS--KRLCMLSETGSSNVSAAFVT--------------STHATKRKSLPRELAEAT
SQQHLDELPPPAQELLDEIEQLKQQQVSSLASHE-----NTARDLSV-T--NKDKKHLEE
----QETNSSKDSSF-LSSREIQD-LEDTERAHSSLDEDLERFLQSPEE-NTALLDPTK-
GSTR-EKKNKDQDVVEQKRKKKESIKPERRESDSSL-GTL-------EE-DELKPCFWKR
LGWSE------P----------------SRIIVLDQSDLSD-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------LPSLLMSFYFLCS
KLRHPHLLQLMAVCLSSDLEKTRLVFERVNFGSLYSILHERRSEFPIIHMETIVHILLQV
SDALRFLHSCGFVHRTVSSYAVVIVLPGEAKLTNLEYMIES-KDGGE--HSDLTRVPIPS
QLYKWCAPEVILERPATTKSDIYSFCVLMQEALT--GMFMTLVTR---------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---

--MSRAIHLPVPCPVQLGTLRNDSLEAQLHEYVKQGNYVKVKKILKKGIYVDAVNSLGQT
ALFVAALLGLTKLVDVLVDYGSDPNHRCFDGSTPVHAAAFSGNQWILSKLLDAGGDL RLH
DQKGRNPQTWALTAGKERSTPM--VEFMQ-RCASHMQAII-QGFS-YDLLKKIDSPQRLI
CSPPWFGGLMQGNP---NGSPNRL--LKAGVISAQNIYSFGFGK----------------
------------------------------------FYLTGG-TQLAYLGSLPVIGEKEV
IQADDEPTFSFFSGPHMVMTNLVWNGSRVTVKELNLP-THPHCSRLRL ADLLIAEQEHSS
KLRHPHLLQLMAVCLSQDLEQTRLVYERVTVGTLFSILHERRSQFPMLHMEVIVHLLLQI
SDALRYLHSRGFIHRSLSSYAVHIVSPGEARLTNLEYMMES-RDGGV--HRDLTRVPLPA
QLYNWAAPEVILQKAAAVKSDIYSFSVMIQEILT--DNIPWNGLDGSVIKEAIVLGNYLE
ADVRLPKPYYD-IVKSGLQVKQKDRTMNLQDIRYILKNDLK----DFIEAQRTQPTESSR
VQRYELHPDVSVYLGLTSEHPKETPDLEIKEL----------KET-GSQLHSPRSHFSPT
EEK-RTPDPQAPGPSLSAKETQNHD----------------TPDPFVA-EEASSP---SV
GQASLYSFEINEIYSG-CLNLEDDKEEEPPGAASSLEGNRPN-QADE-LKSMEEE-----
-LDKME-REACCFCDEHE-----SSSEADTVLSFEDWDWQNASLGSLSLAEPTREDKGNV
SNRSMTE-EYISKCVLNLKIAQTLMHQNASLLRNTQQKIDKLEMIQKEQE--ERTSLWAT
-------S------REFANVYN---LPSAMGPPASSYNPPVVQQLGGQQP-DNRGNCPTL
ERFPR-------------------------------------------------ILLTLC
GPGKQNMGKQFQPAQGAKDSLERS-RNQNTSSQGRP-REFSTQAKVTQ-RNSA--LFTVS
SHQQGLPGSHSPHQDATT---ISMESVSSEIYNAKSR--------NNKDDGEVHLKWKME
VREMAEKAATGQLTVPPWHPQSSLALESEA----ENEPNPLLQPP--------------I
RGSENMDWQ---------QVVEYRREDD-PGGN--DKFDKTDNSDGARDLCG-RQPGPRS
FTSIRHLSPR------------ENEQPEHNEA------FQASSDACVLIEKS----YSDQ
SMQSTCSPESSE---DITDEFLTPDHEYFYSTTAQENLALETSS--PI-EQDFEGIQSAF
AQ------PQASG-EEKFQVTKIL-GKNAEILTRSNFQPIQSAEGE----QEETLKES--
-PKELKEKDISLTDIQDLSSISCEQDSSFKETSCKTPKINHAPTSVSTPLSP---GSMSS
ATSRYKDCLESITFQ-VKTGSTSYRDSQESIPTLSDKFTTVQ-EKAKSLDSLLTSSVTPP
SRLTDL--KRLSSFTGAGSSNIAKASD-I-------------SPQTTQRRSLP--KVEAI
SQHLIDELPPPSQELLDEIEHLKQQQASSTVLD-EY----TAGDPSI-T--PNDKRHLEE
----QETDGNKE-DSILWTKETQDLGEDTERAHSSLDEDLERWLQPPEE-SMELPDLAK-
SSPR-ETNTKDQEVGEKKIKREESIKPERRKSESFL-GTS-------EE-DELKPCFWKR
LGWSE------P----------------SRIIVLDQSDLSD-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---

------------------------------------------------IYVDAVNSCGQT
ALFVAALLGLKKLVDVLVDYGSDPNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX--VVEFMQ-RCASHMQAVI-QGLS-HDLLKKIDSPQWLI
CSPPRFGGLIQGNP---NGSPNRL--LKAGVISAQNVYSF-FGS----------------
------------------------------AVLWCQFYLTGG-TQLAYLGSLPVIGEKEV
VQAXXXXXXXXXXXXXXXXXXLVWNGSRVTVKELDLP-THPHCSRLRLADLLIAEQEHCS
KLGHPLLQL--MVSLSQGSERPWLVYQRVTVGNLFCLLHDRE---------VIAPPPLQN
SDALRFLHSRGFVHRSLSSYAVHIVSMGEPRLTNLEYMMES-RDRGV--HRDLTRVPLPS
QLYNWAAPEVILQKAATTKSDIYSFSMIIQEILT--DNIPWNGLDGSVIKEAIVLXXXXX
XXVRLPKPYYLYIVKSGIQVKQKDRTMNLQDILYILKNDLKASSKDFIGTQRTQPTESPR
VQRYEFHPDVNVYLGLTSEHPKETPDLEIQEL----------KET-GSQPHSPRGHFSPT
ERA--ALDPLAPDLSLTAKETRNQDA--------------PSPA-PFVAEEPRSP---ST
DQASLCSFEINEIYLR-CLNSGDDKEEESPGAASSLEKDRSN-QADE-LKSMEEE-----
-LDRME-KEARCFCDEDE-----SSSEADTELSFGDWDWQSGSLSSLSLPEPTRDAKDNV
NNWSMTE-EYISKCVLNLKISQAIVHQNDELLNSIQKKMDELEMIQKEQED--DWTLWAT
-------S------REFAHVCD---WPSAVGPPTSNYVPPVMQLSGDHLL-DTSGSCPTL
ARTP---RTLSI--------------------------------------------RFAC
--GKQNTGEQ--QPTGVKDSLESK--TQDTSSQGRL-RESGARAKVTR-LNS---VFTTS
HHPHGLSGSPSSCRNSSR---ISMESVSSKIHSAKSR--------NNEDDGEAHLKWKRE
VKEIAEKAATGQLIVPAWHPQSGLPLETKT----ENEPHPLLQPP--------------I
RGPENMHWQ---------RVVECHSENDEPGGND--KSSKRDN--NDSDQYG-RQLGPQN
FTGLSHLSPR------------KNKQSAHGEV------FQASSDASLIIEQS----YSDQ
SVQSTCSLESSD---DITDEFLTPDREYFYSSTAQENLALETSS--PI-EENFEETQGAC
AQ------PLDSG-EKKFQMRTIL-KKNAGILTRSQFQPIQSTEGE----QEETLKES--
-PKELKEKDISLTDIQDLSSISYEQDGSFKEASCKTPKINHAPTSVSTPLSP---GSISS
AASQYEDCLENITFQ-VKTGSASCWSSQEPIRTLSDKCTTVQ-EKARSLDSLFTSSQTPL
SRATDP--XXXXXXXXXXXXXXX--XXXX-------------XXXXXXXXXXXXXXXEAI
SQRHIDELPPPSQELLDEIXXXXXXXXXXXXXXX-----XXXXXXXX-X--XXXQRCLEE
----QETDSKKEDSNVLWIKESEDLCEDTERAHSTLDEDLERWLQLPEE-RLELQDLAK-
GSAR-ETNVKDQKADEKKRKGEESIKPERK-SESFL-GS--------TE-DELKPCFWKR
LGWSE------P----------------SRIIVLDQSDLSD-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------IRIFLLCS
KLRHPHLLQLMAVCLSNDLEKTRLVYERVNFGSLYSILHERRSEFPVLHMETIVHLLLQV
NDALRFLQSRGYIHRSLTSYAVQIVSAGEAKLTNLEYMIES-KDGGD--HSDLTRVPVPA
QLYRWCAPEVILEKATTVKSDIYSFCIVMQEALT--------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---

--MSRGAPFPVPCPVLLGTFTDDSLEAQLHEYAKQGNCVKLKKILKKGVCVDAVNTQGQS
ALFVAALLGHVKLVDVLVDYGSDPNHRCFDGSTPVHAAAFSGNQWILSKLLTAGGD LRLH
DEKGRNPQAWALTAGKDRSTQ--MVEFMQ-RCTSHMKAII-QGFS-YDLLKKIDSPQRLI
GSPPWFGSLIQGSP---NSSPNRQ--LKPGIISAQNIYSFGFGK----------------
------------------------------------FYLTSG-MQLTYPGSLPVIGEKEV
VQADDEPTFSFFSGPYMVMTNLVWNRSRVTVKELNLP-TRPHCSRLRL ADLLIAEQEHSS
NLRHPNLLQLMAVCLSRDLEKIRLVYERITVGTLFSVLHERRSQFPVLHMEVIVHLLLQV
ADALIYLHSRGFIHRSLSSYAVHIVSAGEARLTNLEYLTES-QDSGA--HRNVTRMPLPT
QLYNWAAPEVVLQKAATVKSDIYSFSVIIQEILT--DSIPWNGLDGSLVKETIALGNYLE
ADVRLPEPYYD-IVKSGIHAKQKNRTMNLQDIRYILKNDL----KEFIGAQKTQPTESPR
GQSYEPHPDVNICLGLTSEYQKDPPDLDIKEL----------KEM-GSQPHSPTDHSFLT
VKP--TLAPQTLDSSLSAQKPDNANV--------------PSP-AACLAEEVRSP---TA
SQDSLCSFEINEIYSG-CLTLGTDKEEECLGTAASPEGDRPN-QGDE-LPSLEEE-----
-LDKME-RELHCFCEEDK-----SISEVDTDLLFEDDDWQSDSLGSLNLPEPTREAKGKT
SSWSKTD-EYVSKCVLNLKISQVMMQQSAEWLRKLEQEVEELEWAQKELDS-QCSSLRDA
-------S------LKFANAKF---Q-PAVGPPSLAYLPPVMQLPGLKQP-ENGGTWLTL
ARSPGNEREFQE----GHFSKK-PEKLSACGWKPF---TQVSEESRGDCSELNNQLPTLC
GPGKQNTGEQLPSTQEAKESLEKN-TNQNS------------------------------
---------------------RSMTSVSSEIYATKSR--------NNEDNGEAHLKWRLA
VKEMAEKAVSGQLLLPPWNPQSSVPFESKV----ENESTPLPRPP--------------I
RGPESTEWQ---------HILEYQRENDEPKGNT--KFGKMDNSDCDKNKHS-RWTGLQR
FTGIRYPFFR------------NHEQPEQNEA------SQASCDTSVGTEKF----YSVS
GTAWQNQGASCD---T------SVGTEKF----------YSTSS--PI-GDDFERFQDSF
AQ------RQGYV-EENFQIREIF-EKNAEIMTKPQFQAIQCAEDK----QDETLGET--
-PKELKEKNISLTDIQDLSSITYDQDGCFKETSYKTPKLKHTPTSASTPLSP---ESISS
AASHYEDCLENTTFH-VKRGSTFCWNGQEAMRTLSAKFTTVR-ERAKSLESLLASSKSLP
AKLTDS--KRLCMLSETGSSNVSAAFVT--------------STHATKRKSLPRELAEAT
SQQHLDELPPPAQELLDEIEQLKQQQVSSPASHE-----NTARDLSV-T--NKDKKHLEE
----QETNSSKDSSF-LSSREIQD-LEDTERAHSSLDEDLERFLQSPEE-NTALLDPTK-
GSTR-EKKNKDQDVVEQKRKKKESIKPERRESDSSL-GTL-------EE-DELKPCFWKQ
LGWSE------P----------------SRIIVLDQSDLSD-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---

------------------------------------------------ICIDAVNSLGQT
ALFVAALLGLTKLVDVLVDYGSDPNHRCFDGSTPVHAAAFSGSQWILSKLLDAGGDLRLH
DEKGRNPHTWALAAGKDRSTPM--VEFMQ-RCALHMQAIM-QGFS-HDLLKKIDSPQRLI
CSPPCLVGLLQGSP---SGSPNRP--LKAGVISTQNIYSFGFGK----------------
------------------------------------FYLTGG-TQLAYLGSLPIIGEKEM
IQADDEPTFSFISGPYMVMTNLVWNGSRVTVKSLNLP-THPHSNKLRLADLLIAEQEHSS
KLRHPHLLQLMAVCLSQDLEKTQLVYERITVGTLFSVLHERRSQFPVLHMEVMVHLLLQI
ADALRYLHSRGFVHRSLSSYAIHIVSAGEARLTNLEYMLES-QDSGG--HRDLSQVPLPT
ELYNWAAPEVIFQKAATVKSDIYSFSMIIQEILT--DDVPWNDLDGSVIKEAILLGNYLE
ADARLPEPYYD-VVKSGIQVKEKDRIMNLQDIQYILKNDLK----ENTGVQRTQPMESPR
VQRCEPYPDVSVYLGLTSQHRKAGLDLEIKEL----------KES-GSQPHSPKDYSSPT
AK--AVLAPQTPDPSLMAQVPQNLAAAAAAVAPPPPPSPPPPPPTSVV-AE---T---SA
SQGSLNSFEINEIFSG-CLNIEIDTEEECPGATSALEDDKPN-QVDE-LQSLEEE-----
-LDKME-EE-AHLCDEDE-----NSSEVDTELFFGDWDWQNNSLSLLSLPKPAREATGKV
SSWSKTE-EYISKCVLNLKISQTMAHEITDLVGNIKQKLNEVELIQKE-----NTSLWTA
-------S------RLFPDVCD---LPRPVGPPTLNYIPPVMQVSGGSHP-DTSGNFPTL
LRSPRRVKEFQG----AYCDKK-PKRSSSYAWKPF---THISEESTEYQAERRHQLSTLC
DPGKQDTGESFQVTQGAKDSLERK-KNQDSR-----------------------------
---------------------NNVESTSSVIS-NVKQ--------GNKDDGKIHLKWKTE
VKETAEKAASGELPVLPWHPQSSLTLKSEA----VCKSGPLLQPP--------------A
RGPETMGWQ---------QGIEFHKEKEETEGYD-VSLVKVDSCSHNSENCG-RQPGPQS
FAGIRHLSLR------------RNEQPEPNGA------FQASSVVSVTAEKS----YNVS
---NMPKPELTF---STFE------LSVF---------------------SHW-------
--------PDKLG-P----CITLY-TVL-TKYF--LYFVSHSAECE----QEKTLKEP--
-PKEMKGKDISLTDIQDLSSISYESDGSFKETLCKTPKVSHAPTSVSTPLSP---GNHKV
LNYFPN------------------------------------------------------
------------------------------------------------YFLKE--LMEAI
SQHQIEELPPPSRELLEEIEQLKQQQASSLVLH-ES----TACHPSI-T--ADDPTHLDE
----QETDSNKEGSSLLWTRESQDVGDDTERAHSTLDEDLERWLQPPEEKNM--------
---K-DTKTKDQDFIEKKTKRKENIKPERRKSESFL-GTC-------EE-GDR-------
LGFIS------P----------------P-------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---

--MSRGAPFPVPCPVLLGTFTDDSLEAQLHEYAKQGNCVKLKKILKKGVCVDAVNTRGQS
ALFVAALLGHVKLVDVLVDYGSDPNHRCFDGSTPVHAAAFSGNQWILSKLLTAGGD LRLH
DEKGRNPQAWALTAGKDRSTQ--MVEFMQ-RCTSHMKAII-QGFS-YDLLKKIDSPQQLI
GSPPWFGNLIQGSP---NSSPNRQ--LKPGIISAQNIYSFGFGK----------------
------------------------------------FYLTSG-MQLTYPGSLPVIGEKEV
IQADDEPTFSFFSGPYMVMTNLVWNRSRVTVKELNLP-TRPHCSRLRL ADLLIAEQEHSS
NLRHPNLLQLMAVCLSRDLEKIRLVYERITVGTLFSVLHERRSEFPVLHMEVIVHLLLQV
ADALIYLHSRGFIHRSLSSYAVHIVSAGEARLTNLEYMMES-QDSGA--HRNMTRMSLPT
QLYNWAAPEVVLQKVATVKSDIYSFSVIIQEILT--DSIPWNGLDGSLVKETIALGNYLE
ADVRLPEPYYD-IVKSGIHAKQKNRTMNLQDIRYILKNDL----KEFIGAQKTQPTESPR
GQSYEPHPDVNICLGLTSEYQKDPPDLDIKEL----------KET-GSQPHSPTDHSFLT
EKP--TLAPQTLDSSLSAQKPDNANV--------------PSPPAACLAEEVRSP---TA
SQDSLCSFEINEIYSG-CLTLGTNKEEERLGTAASPEGDRPN-QGDE-LPSLEEE-----
-LDKME-RELHCFCEEDK-----SISEVDTDLLFEDDDWQSDSLGSLNLLEPTREAKGKT
SSWSKTD-EYVSKCVLNLKISQVMMQQSAEWLRKLEQEVEQLEWAQKELDS-QCSSLRDA
-------S------LKFANAKF---Q-PAVGPPSLAYLPPVMQLPGLKQP-ENGGTWLAL
ARSPGNEREFQE----GHFSKK-PEKLSACGWKPF---TQVSEESRGDCSELNNQLPTLC
GPGKQNTGEQLPSTQEAKESLEKN-TNQNS------------------------------
---------------------RSTASVSSEIYDTKSR--------NNEDNGEAHLKWRLA
VKEMAEKAVSGQLLAPPWNPQSRVPFESKV----ENESTPLPRPP--------------I
RGPESTGWQ---------HILEYQRENDEPKGNT--KFGKMDNRDCDKNKHS-RWTGLQR
FTGIRYPFSR------------NHEEPEHNEA------SQASCDTSV-------------
------------------------GTEKF----------YSTSS--PI-GDDFERFQDSF
AQ------RQGYV-EENFQIREIF-GKNAEILTKPQFQAIQCAEDK----QDETLGET--
-PKELKEKNISLTDIQDLSSITYDQAGCFKETSCKTPKLKHAPTSASTPLSP---ESISS
AASHYEDCLENTTFH-VERGSTFCWNGQEAMRTLSAKFTSVR-ERAKSLESLLASSKSLP
AKLTDC--KRLCMLSGTGSSNVSAAFVT--------------STHATKRKSLPGELAEAT
SQRHLDELPPPAQELLDEIEQLKQQQVSSMASHE-----NTARDLSV-T--DKDKKHLEE
----QETNSSKDSSF-LSSREIQD-LEDTERAHSSLDEDLERFLQSPEE-NTALLDPTK-
GSTR-EKKPKDQDVVEQKRKKKESIKPERRESDSSL-GAL-------EE-DELKPCFWKR
LGWSE------P----------------SRIIVLDQSDLSD-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---

--MSRAIPLPLPCPVQLGTLRNDSLEAQLHEYVKQGNYLKVKKILKKGIYVDAVNNLGQT
ALFVAALLGLRKLVDVLVDYGSDPNHRCFDGSTPVHAAAFSGNQWILSKLLDAGGDL RLH
DERGQNPKTWALTAGKEHSTQ--IVEFMQ-RCALHMQAII-QGFS-YDLLKKIDSPQRLV
YSPPWFGSLVQGNP---NGSPNRL--LKAGVISAQNIYSFGFGK----------------
------------------------------AMPWFQFYLTGA-TQIAYLGSLLVIGEKEV
IQADDEPTFSFFSGPYMVMTNLVWNGSRVTVKELNLP-THPHCSKLRL ADLLIAEQEHSS
KLRHPYLLQLMAVCLSQDLEKTRLVYERITIGTLFSVLHERRSQFPVLHMEVIVHLLLQI
SDALRYLHSQGFIHRSLSSYAVHIVSPGEARLTNLEYMLES-KDRGE--QRDLTRVPLPT
QLYNWAAPEVILQKAATVKSDIYSFSMIIQEILT--DDIPWNGLDGSVIKEAIVLGNYLE
ADVRLPKPYYD-IVKLGIHIKQKDRTMNLQDIRYILKNDL----KDFTGTQRTQPTESPR
VQRYGLHPDVNVYLGLTSEHTRETPDMEIIEL----------KEM-GSQPHSPRVHSL-F
TDG--TLDPQAPDPCLMARETQNQDA--------------PCPT-PFMAEEANSP---ST
GQASLCSFEINEIYSG-CLTLEDDI-EEPPGAASSLEADGPN-QVDE-LQSMEEE-----
-LDKME-REACCFCSEDE-----SSSKAETEYSFEDWDWQNGSLSSLSLPESTREAKSNL
NNRSMAEEYLISECVLDLKIMQTIMHENDDRLRNIEQILDEVEMKQKEQEE--RMSLWAT
-------S------REFTDVYS---LPPAVGPPSLNYIPPVLQLSGGQQP-DTSGKCPTL
PRFPRM-------------------------------------------------LPTLC
DPGKQNTDEQFQGTQGVKDSLGRS-RIQNTSSRGKP-RESTAQAKATQ-FDSA--LFTLS
SHWQGPSAPPTSHWDSAR---MSVDPVSSEIYNAESR--------N-KDDGEVHLKWKME
VKEMAEKAATGQLTVPPWHPQSSLTLESEA----ENEPDALLQPP--------------I
GSPENTDWQ---------RVIEYHRENDEPRGNA--KFDNTGSNDYDSDQHD-RQPRPGS
FTSIRHPSPR------------QKEQPEYSEA------FQASSDALVAVEKS----YSHQ
SMQSTCSPESSE---DITDEFLTPDDEYFYSSTAQENLALETSS--PI-EEDFEGIQGAF
AQ------PQVSG-EEKFQMRKIL-GKNAEILPRSQFQPIRSTEDE----QEETSKES--
-LKELKEKDISLTDIQDLSSISYEPDSSFKETSCKTPKINHAPTSVSTPLSP---GSVSS
AASQYKDCIESITFQ-VKTESASCWNSQEFIQTLSDEFISVR-ERAKKLDSLLTASETCP
SGLPSL--KRLSSFIGAGSSSLVKACDSS-------------PPHATQRRSLPK--VEAF
SQHHIDELPPPSQELLDEIELLKQQQGSSTVLHE-----NTASDAGG-T--ANDQRHLEE
----QETDSKKEDSSMLLSKETGDLGEDTERAHSTLDEDLERWLQPPEE-SMELQDLPK-
GSER-EINIKDQEVGEDKRKRENSITPERRKSESVL-GTS-------EE-DELKPCFWKR
LGWSE------S----------------SRIIVLDQSDLSD-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---

--MSRAVPLPLPCPVQVGTLRKDSLEAQLHEYVKQGNYLKVKKILKKGIYVDAVNNLGQT
ALFVAALLGLRKLVDVLVDYGSDPNHRCFDGSTPVHAAAFSGNQWILSKLLDAGGDL RLH
DERGQNPKTWALTAGKEHSTQ--IVEFMQ-RCASHMQAII-QGFS-YDLLKKIDSPQRLV
YSPPWFGGLVQGNP---NGSPNRL--FKAGVISAQNIYSFGFGK----------------
------------------------------AMPWFQFYLTGA-TQIAYLGSLLVIGEKEV
IQADDEPTFSFFSGPYMVMTNLVWNGSRVTVKELNLP-THPHCSKLRLADLLIAEQEHSS
PRPR----HLIGLGLSTDPEHRHLL-----------TNYNPRS QFPVLHMEVIVHLLLQI
SDALRYLHFQGFIHRSLSSYAVHIVSPGEARLTNLEYMLES-KDRGE--QRDLTRVPLPT
QLYNWAAPEVILQKAATVKSDIYSFSMIMQEILT--DDIPWNGLDGSVIKEAIVLGNYLE
ADVRLPKPYYD-IVKSGIHVNQKDRTMNLQDIRYILKNDL----KDFTGTQRTQPTESPR
VQRYGLHPDVNVYLGLTSEHTRETPDMEIIEL----------KEM-GSQSHSPRVHSL-F
TEG--TLDPQAPDPCLMARETQNQDA--------------PCLA-PFMAEEASSP---ST
GQASLCSFEINEIYSG-CLTLEDYV-EEPPGAASSLEADGPN-QVDE-LQSMEDE-----
-LDKME-REACCFCSEDE-----SSSKAETEYSFEDWDWQNGSLSSLSVPKSTREAKSNL
NNSSMTEEYLISKCVLDLKIIQTIMHENDDRLRNIKQLLDEVEMKQKEQEE--RMSLWAT
-------S------REFTDVYN---LPPAVGPPSINYIPPVLQLSGGQQP-DTSGKCPTL
PRFPRM-------------------------------------------------LPTLC
DPGKQNADEQFQGTQGVKDSLERS-RIQNTSSRGKP-RESTAQAKATQ-FNSA--LFTLS
SHLQGPSASPNSHWDFTR---MSVDPVSSEIYNAESR--------N-KDDGEVHLKWKME
VKEMAEKAATGQLTVPPWHPQSSLTLESEA----ENEPDALLQPP--------------I
GSPENTDWQ---------RVIEYHRENDAPRGNA--KFDNTGNNDCDSDQHD-KQPRPGS
FTSIRHPSPR------------QKEQPEYSEA------FQASSDALVAVEKS----YSHQ
SMQSTCSPESSE---DITNEFLTPDDEYFYSSTAQENLALETSS--PI-EEDFEGIQGAF
AQ------PQ-----EKFQMRKIL-GKNAEILPRSQFQPIRSTEDE----QEETSKES--
-LKELKEKDISLTDIQDLSSISYEPDSSFKEASCKTPKINHAPTSVSTPLSP---GSVSS
AASQYKDCIENITFQ-VKTESASCWNSQEFIQTLSDEFISVR-ERVKKLDSLLTASETCP
SRLPGL--KRLSSFIGTGSSSLVKACDSS-------------PPHATQRRSLPK--VEAF
SQHHIDELPPPSQELLDEIELLKQQQGSSTVLHE-----NTASDAGG-T--ANDQRHLEE
----QETDSKKEDSSMLLSNETGDLGEDTERAHSTLDEDLERWLQPPEE-TMELQDLPK-
GSER-ETNIKDQEVGEDKRKREDSITPERRKSESVL-GTS-------EE-DELKPCFWKR
LGWSE------S----------------SRIIVLDQSDLSD-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------ISKISA---EKPLIKY--CKYGGILTNAISSFGYGK----------------
------------------------------------LYFTND-NHLSCMAYIPYIEERDL
VQGHDKPVFSFSTGHYMTMTNLMWGYTEVTVKEL-MS-THQNCGKLHFADLLIAEQEYMS
KLHHPHILQLLAVCLSHDLEKTCLVFERVMFGTLYSILHERRTEFPVLHMETILNILLQV
IDALIFVHWRGFIHCSFSSHAINIILPGLAKLSNFEFMAES-KDGKV--RTDVSHFPIPK
YLYRWSAPEVILGKTISTKSDLFSFCVVMQESLT--DTLPWDGLDCFAVKNAVISGHNLA
VDLRIAKPYDK-IVSTGIQAMAKDRTMSLQDILWKLRKDI----EESRKSAS----ETLD
IECHNRYPDVTNLFHPRGTLNKEPHNLQTDTLDNDKTFSEEVTEI-RCKCGPVLTCHLNS
ENL---------NKQALHTETHHS-------------------------GLVCDSAHEFQ
NKDTISGAEVNAFYEMKYLDYQLDNERT-----------KP---------DMFKNTYNM-
ESCAEEKHVISCSVS-PK-----RSAETDSESNTEEINSLCEITDTAEDNQITDKARR--
--PSSLQ-KHIRSTTEKLKISQTLLEKINKALDSVEKSLKKSDNTHVQTYK-KLSEECVS
CKASDEISRDEVDYMNGQLKIKSNTVRSALGPPSQYKPPRLDHMYTQRDK---KNFQSE-
---------YA-------MGARLKTVKKQLSWKDY---CSHQTSSNGREENCNKA-HRK-
----------YAEK-------DKD-LKDS----------------NT-------------
--------------EPND---RCSEAYSEELFYAKANVCEGRTKYVGRTIGMASSEWTST
R-----------LQSPQPCIARNPTKECGT----ASDIL---------------------
----SNDFNIGLDN------------SSICPGDE--FFTANFELSCCS--ND-QYPGLES
LKIREEINLTQSASNLILCPSGSYKQAESGSDQLEMTAVEVNTLSFIHHTSSVVDIQELS
TIQLPI--SKAG---KVSTRFSTPVAGKVA----------------PI--AAVSLLFRAH
ST------LDDAL-ERIMH----L-Q----------AMETDVTDGMSKL-----------
-----------------------DQDGPQE------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---

--MSRAVHLPVPCPVKLGSLRNDSLEAQLHDYVKQGNYVKVKKILKKGIYVDAVNSLGQT
ALFIAALLGLTKLVDILVDYGSDPNHRCFDGSTPVHAAAFSGNQWILSKLLDAGGDLRLH
D EKGQDPQTWALTAGKERSTAV--VEFIR-RCASHMQAII-QGFS-RDLLKRVDSPQRLI
CSPPRFGGLMQGSP---NGSPNRL--LKAGVVSAQNIYSFGFGK----------------
------------------------------VVLCFQFYLTGG-TQLAYLGSLPVIGEKEV
IQADDEPAFSFCSGP YMVMTNLVWNGSRVTVKELGLP-THPNCSRLRLADLLIAEQEHSS
KLRHPHLLQLMAVCLSQDLERTRLVYERITVGTLFAVLHERRSQFPVLHMEVIVHLLLQI
SDALRYLHSRGFIHRSLSSYAIHVVSTGEARLTNLEYMLES-QDRGV--HRDLTRVPLPT
QLYNWAAPEVVLQKAATVKSDIYSFSMIIQEILT--DNIPWDGLDGSVIKEAIVLGNYLE
ADVRLPKPYYD-IVKSGIQVKQKDRTMNLQDIRYILKNDLK----DLIGAQRTQPAESSG
VQRYELHPDVNVYLGLTSEHPKETSDLEIKEL----------KEA-GSQLHSPRSQSSPV
GK--ATPDPQAPDPNLMAEETQNQDA--------------ASPACSMA-EEARSP---SP
GQASLCSFEINEIFSG-CLDVGDDKEE-SPGAGSSVEGTRPN-QGNE-LKSLEEE-----
-LEKME-REACCFYDEDE-----SSSEADTELSFEDWDWQNGSLSSPSLPEPAREANGNT
SNMSMTE-EYISKCVLNLKIAQMM-HQNADLRKTXXXXXXXXXXXXXXXX--XXXXXXXX
-------X-----------------XX--XX---XXXXXXXXXX-X-------XXXX-XX
X---X--------------------------XXXXXXXXXXXXXXXXXXXXXXXXLPTLC
GPGKQSTGEQFQPTPGAKDSLERN-RNQNTSSQEKP-RESSAQAKVTQ-LNSA--LFTMS
-NPQGPLVASRRSTR------TAAESVSSEMYNTKS---------RNEDNGKVHLKWKXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----XXXXXXXXXXX--------------X
XXX-XXXXX---------XXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXX-XXXXXXX
XXXIRHLSLR------------KNKQPEHNQV------LQVISEASVIIEKS----YSDQ
SVQSTCSPESSE---DITDEFLTPDHVYFYSSTTQGNLALETSS--PIVEEDFHRMRDAF
AQ------PQGAG-EEKVQMRKNL-GKNAEILTRSQFHPIRSTEGE----QEETLKES--
-PKELKEKDISLTDIQDLSSISYEQDGSFKEVSCKTPKINHAPTSVSTPLSP---ESISS
TASCYKDCLESIPFQ-VKTGSTSCQNSQESIRTLSDKFTTVR-EKAKSLDSLLTSSETLP
SRLTDL--KRLSSFTGAGSSSSVKAPD-T-------------SSHTTQRRSLQ--KVEAI
SKHHTDELPPPSQELLDEIEHLKQQQASSTVLE--N----TASPLGI-I--ANDQRHLEE
----QENNSKKEDSSMLWTKETQDLEEDTERAHSTLDEDLERWLQPPED-STEPQDLPK-
GSAR-ETNTKDQEVGEKKKKEEEGIKPERRKSESFL-GTS-------EE-EELKPCFWKR
LGWSE------P----------------SRIIVLDQSDLSD-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---

--MSRAVHLPVPCPVQLGSLRNDSLEAQLHEYVKQGNYVKVKKILKKGVYVDAVNSLGQT
ALFIAALLGLTKLVDVLVDYGSDPNHRCFDGSTPIHAAAFSGNQWILSKLLDAGGDLRLH
D ERGQSPQTWALAAGKERGTAM--VEFMQ-RCAAHMQAII-QGFS-YDLL-KIDSPQRLI
CGLPRFGGLMQGSP---NGSPNRL--PKAGVISAQNIYSFGFGK----------------
------------------------------AVLCFQFYLTGG-TQLAY LGSLPVIGEKEV
IQADDEPAFSFFSGPYMVMTXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXX
KLRHPHLLQLMAVCLFQGLQKTRLVYERVAVGTLFSVLHERRAQFPVLHMEVIVHLLLQT
SDALRYLHSRGFIHRSLSSYAIHIVSTGEARLTNLEYMMES-RDGGV--HKDLTRVSLPT
QLYNWAAPEVILQKAATVKSDVYSFSVIIQEILT--DSIPWDDLDGSVIKETIVSGNYLE
ADVRLPKPYYD-IVKSGIQVKQKDRTMNLQDIQYILKNDLK----DFIGAQRTQPTESPR
VQRYELHPDVNVCLGVTSEHP-----LQIKEL----------KEA-GGQLHSPRGHSTLT
KK--ATPEPLVPDPSLEAQETQNQDA--------------ASSACSVG-EEARSS---SP
DQASLCSFEINEIYSG-CLDMGDDKEEEPPGTGSSLEGARQN-QVDE-LKSMEEE-----
-LEKME-REACCFSHEDS-----SSSEADTELSFEDWGWQSGSLSSPSLPEPARGAKGNV
SNRSLTE-QYISKCVLNLKISQTLMHQNANLLRSIQQKTDKLEMTQKEQE---GRSLWAS
-------S------REFANGYD---WPSALGPQASSYIPPAMQLPGNLQP-DTEGNCPTL
AKSPR-------------------------------------------------TVPSLC
GPGKQSRGEQFQPTHGAKDSLERN-RNQNTSSQGRP-RESSAQTRTTQ-LSGA--LLTVP
GHPQGPLTSSTPGRGSSR---ISMESVSSKICNTKSR--------NNEDAGEIHLKWKTE
VKEMAEKAATGQLAVPPWHPQSSVTLENEA----ENRPDPLLQPP--------------I
KVPEHVDWQ---------QAVEHPKKNDEPGGN--GKCDKTDSSDRNSDQHG-RQPGPRS
STGTRHLPPR------------KNEQPEHGEV-------QESSDVPVVVEKS----YSDQ
SVQPTCSPESSE---DITDEVLTTDHEYFYSSTAQENLALETSS--PI-EEDFEGIQHAC
AR------PQASXXXXXXXXXXX--XXXXXXXXXXXXXXXXXIEDE----QEETLKES--
-PKEMKEKDISLTDIQDLSSISYEQGGSFKEVSCKTPKINHAPTSVSTPLSP---GSISS
ASSQYKDCLESITF--VKTGSTSFWKSQ-SIQTLSDKFTTVR-EKAKSLDSLLTSSETLP
-RLTNL--KRLPAFTGAGSSSIAKAPD-T-------------SSRATQRRSLPKXXXXXX
XXXXX--XXXXXXXXXXXXXHLKRQQASSTVRD-EN----TASHLGI-T--ASDQRHLEE
----QETNSNKEDSSMLWTKETQDLEEDTERAHSTLDEDLERWLQPPED-STELQGLPK-
CSAX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXX-------XX-XELKPCFWKR
LGWSE------P----------------SRIIVLDQSDLPD-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---

--MSRAIQIPVPCPVQLGTLTDDSLEAQFHEYVKQGNYVKVKKILKKGIYVDAVNTLGQS
ALFVAALLGHMKLVDVLVDYGSDPNHRCFDGSTPVHAAAFSGNQWILSKLLAAGGDL RLH
DEKGRNPQTWALAAGKDCSTQM--VKFMQ-RCTSHMKAII-QGFS-YDLLKKIDSPQQLI
CSAPWFGNFMQGSP---NSSPNRQ--LKPGIISALNIYSFGFGK----------------
------------------------------------FYLTAG-MQLTYPGSLPVIGEKEV
IQADDEPTFSFFSGPYMVMTNLVWNK SRVTVKELNLP-THPHCSNLRLADLLIAEQEHSS
NLRHPNLLQLMAVCLSQDLKKIRLVYERITVGTLFSVLHERRSQFPVLHMEVIVHLLLQI
ADALIYLHSRGFIHRSLSSYAVHIVSAGEARLTNLEYMMVS-QDSGV--HRDMTQVPLPI
QLYNWAAPEVILQNAATVKSDIYSFSVIIQEILT--DSIPWNGLDGSLIKETIVLGNYLE
ADARLPDPYYD-IVKSGIHVKQKNRTMNLQDIRYILKNNLK----EFIGTQRTQPPESPR
VQRYEPHTDGNTCLRLTSEYQKDAPDLDIKEL----------KEM-GSQPHSPRSHSFPT
EK--TTLAPQVLDPSLSAQEHQNPNV--------------PSSLASCLEEEARNS---TS
SQASLCSFEINEIYSG-CLNLHADKEEEHPETVSSLEEGNKPNQVDE-LPSLEEE-----
-LDRME-RELHCFCEEDK-----SFSEVDTDFSFEDGDWQSDSFSSLSLPQPTREAKGKM
SSWSKTD-EYVSKCVLNLKISQVIMQQNAEWLKKLDQEIDELELGQKELDK-QCRILWDV
-------S------ERFSNAK----IPLAVGPPSLTYHSPVMQLSEPQQS-ENCDRWSTM
ARSPKTVRDFQG----DHFGKR-PEKQSDCSQKPF---TQVSEESNRDQSETSNQLSTLG
GLGKQNTDEQLPSTEGSKESLERS-RNQNS------------------------------
--------------------RINMESVSSEIYNTKSR--------YNEDDGEVHLKWKIA
VKEMAEKAVSGKLPVSPWNSQNSLPLNHEV----ENETALLPQPP--------------V
RGPENIDWQ---------HVVDYHRENEEPEGN--MKFGKMDNSDYNRDKHRRRQPSLQS
FTSIGHLSFR------------KHEQLQHSEA------SQASCDTSVGNEKF----CST-
------------------------------------------SS--PI-EENFEGIHSSF
AQ------PQSYV-EEKFQIREIF-GKNAEILTEPRFQPTQCIEDE----QEQTLKEA--
-PKELKEKDISLTDIQDLSSISYEQDGYFKETSCKTPKLNHAPTSVSTPLSP---ESISS
TASHYEDCLENSTFQ-VKTGSTLCWNSQESMRTLSVKFTTVR-ERAKSLESLLASSRTLP
ARQIDP--KKMSACALAAASNISIASV-T-------------STHATQRKSLPRELVEAT
PQHHIDELPPPAQELLDEIEHLKQRQVLSMESQEN-----TAHDLSV-T--ENDQKHLDE
----QETDSSKD-SSFLSTKDIQDLEEDTERAHSSLDEDLERLLQSPEQ-SMELLDPSK-
GSTR-ETKNKDQEVVEQKRKRKESTKTERRKSDSFL-GTS-------EE-DELKPCFWKR
LGWSE------P----------------SRIIVLDQSDLSD-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---

-----------------------------------------------GTFVDAVNSMGQT
PLFTAALLGLGKIVDVLLDYGSDPNHRCYDGSTPVHAGAFSGNQWILSKLLDEGGDLRVH
DKDGKNPQCWAMSAEKESGAQM--LEFIQ-RCTFHMQAAI-QNFP-CDQFRKVCSSKALV
CSPSRFGGLVQGNV---DNPLGRF--LKGGDNAGRNIYSFGFGK----------------
------------------------------------FYLAGS-RHLGYLASLPIIGEREV
VQADDEPTFSYHVGPCMIMTNLMWGSSRVTVKELSFE-PHQNCSKLRLADLLIAEQEHSS
KLRHPHLLQLMSVCLSSDLEKIRLVYERVNFGSLYSILHERRTEFPVLRMETILHVLLQI
NDALRFLHSRGFIHRSITSHAIQIVSSGEAKLCNMEYMIES-KDGGE--HSDLTRIPVPV
QLFKWCSPEVILEKAVTVKSDIYSFCTVMQEALT--ETLPWKGVEDSVIKQLIMSGQHLE
ADVRLPIPYYG-IVKSGLEPKQKNRSMNLQDIQYILKNDLK----DLTKSQTGHTDEMSK
VQRPAVFADINICLASAFSYQKRTLGLHEKEV----------TEA-GNSSPAPRYSLIPE
ENN-ALVDYEASSNLQPVAQEKNHDI-------------------DSEVQATCSV---SD
VDDSLCSFEMNEIFAS-YPESQEDFLEEGAGVGQTLKDKEKQQKVKD-KPALRDL-----
-F-----VSPGASCEEKPASEEGSFSDSVTEDTTEEEEGASEVSDLCLLAQVRGDAGRRM
SGPSPDE-QHISKCVLNLKIIQSMLQQAADSLCRTELKLDKFIANERQNKLLQEIGMYQV
S------K------QTFNDRH---WNRKAIGPPSSDYIPPLTAQLIINRV-PNVLNH---
----GLLDSFQHLL---------PRVSVRCK----------------------NKFNLQC
QRGSDSHSAASG-------------ISQKPSVQLGPYRDSLSAAELTGQI-ANAFLIEVS
SLKLTVPKESNL-------IVKCYPKSASEIYSTKI----------SEERRMRQPEWRNE
VKQMAKRVASGQLELISTNPTSECTSESETESI----EEAFQHVV--------------I
RVQKSRDQQ---------R--ERWRAGDNVEPWD-VGCEDRSASENTKNTQTSKTGGTCF
LDLFTSLSVR------------SLHLLPFSPL------LQTSN-LGDKLE----------
---------------DRCDGLLQRRKS----------------------EDAGSGIQVSG
KCVLSSEDPLESG-RQNFVSISVL-SLNCKRINEYDLFPHSSGEAA----QELVSREL--
-QEDSKEKDISVTDIQDLSSIPCEE-NYYKNINCKTPRVSHAPTSVSTPLRS---GNCS-
DKKCKKHCLDWCLFKYKKPFSTSLKCCQ-EVSAVSRTFTTAYEER-RSTENTSTPVEEKK
VKVVWM--QRISVQLSVHSVEMNKECVAD-------------NILMTSKKSLS--ALSQA
PNHFIDDLPPPAQELLDEIEYLKQQDSITQDFEEKG-----LFDCGM-Q--INGQIKMED
RDTKKEIDQNEKRDHSVLTKEAFNLAEETERAHSTLDDVLERILHAVPA-DEEIQEQPQ-
G-----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---

--MSRAVPLPLPCPVQLGTLRNDSLEAQLHEYVKQGNYLKVKKILKKGIYVDAVNNLGQT
ALFVAALLGLRKLVDVLVDYGSDPNHRCFDGSTPVHAAAFSGNQWILSKLLDAGGDLRLH
DERGQNPKTWALTAGKERSTQ--VVEFMQ-RCASHMQAII-QGFS-YDLLKKIDSPQRLV
YSPPWFGSLVQGNP---NGSPNRM--LKAGVISAQNIYSFGFGK----------------
------------------------------AMPWFQFYLTGA-TQIAYLGSLLVIGEKEV
IQADDEPTFSFFSGPYMVMTNLVWNGSRVTVKKLNLP-THPHCSKLRLADLLIAEQEHSS
KLRHPYLLQLMAVCLSQDLEKTRLVYERITIGTLFSVLHERRSQFPVLHMEVIVHLLLQI
SDALRYLHSQGFIHRSLSSYAVHIVSPGEARLTNLEYMLES-KDRGE--QRDLTRVPLPT
QLYNWAAPEVILQKAATVKSDIYSFSMIIQEILT--DDIPWNGLDGSVIKEAIVLGNYLE
ADVRLPKPYYD-IVKSGIHVKQKDRTMNLQDIRYILKNDL----KDFTGTQRTQPTESPR
VEKYGLHPDVNVYLGLTSEHTRETPDMEIIEL----------KEMVGSQPHSPRVHSL-F
TEG--TLDPQAPDPCLMARETQNQDA--------------ACPA-PFMAEEASSP---ST
GQASLCSFEINEIYSG-CLTLEDDI-EEPPGAASSLEADGPN-QVDE-LQSMEEE-----
-LDKME-REACCFCSEDE-----SSSKAETEYSFEDWDWQNGSLSSLSLPQSTREAKSNL
NDRSMAEEYLISKCVLDLKIMQTIMHENDDRLRNIEQILDEVEMKQKEQEE--RMSLWAT
-------S------REFTDVYN---LPPAVGPPSLNYIPPVLQLSGGQQP-DTSGKCPTL
PRFPRMLF----------------------------------------------KLPTLC
DPGKQNTDEQFQGTQGVKDSLERS-RIQNTSSRGKP-RESTAQAKATQ-FDSA--LFTLS
SHWQGPSASPNSHWDSTR---MSVDPVSSEIYNAESR--------N-KDDGEVHLKWKME
VKEMAEKAATGQLTVPPWHPQSSLTLESEA----ENEPDALLQPP--------------I
GSPENTDWQ---------QVIEYHRENDEPRGNA--KFDNTGNNDCDSDQHD-RQPRPGS
FTSIRHPSPR------------QKEQPEYSEA------FQASSDALVAVEKS----YSHQ
SMQSTCSPESSE---DITDEFLTPDDEYFYSSTAQENLALETSS--PI-EEDFEGIRGAF
AQ------PQVSG-EEKFQMRKIL-GKNAEILPRSQFQPIRSTEDE----QEETSKES--
-LKELKEKDISLTDIQDLSSISYEPDSSFKEASCKTPKINHAPTSVSTPLSP---GSVSS
AASQYKDCIESITFQ-VKTESASCWNSQEFIQTLSDEFISVR-ERAKKLDSLLTASETCP
SRLPGL--KRLSSFIGAGSSSLVKACDSS-------------PPHATQRRSLPKELVEAF
SQHHIDELPPPSQELLDEIELLKQQQGSSTVLHE-----NTASDAGG-T--ANDQRHLEE
----QETDSKKEDSSMLLSKETGDLGEDTERAHSTLDEDLERWLQPPEE-SMELQDLPK-
GSER-EINIKDQEVGEDKRKREDSITPERRKSESVL-GTS-------EE-DELKPCFWKQ
LGWSE------S----------------SRIIVLDQSDLSD-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---

--MAHVPPLPIPCPVQLGSLKGDSLEAQLHECVRQGNCRKVKKLLKKGTFVDAVNSMGQT
SLFTAALLGLGRIVDVLLDYGSDPNHRCYDGSTPVHAAAFSGNQWVLSKLLDEGGDLRVH
D EGGKNPQYWAMSAGKESSAQM--LEFIQ-RCTFHMQAA-IQNFP-CDILRKVCSSKALV
SSPSRFGGIVQGNA---DSPLGRF--LKGGVNAAKNIYSFGFGK----------------
------------------------------------FYLAGS-GHLGY LASLPIIGEKEV
VQADDEPTFSYRVGPCMTMTNLMWGSSRVTVKELSFQ-PHQNCSKLRLADLLIAEQEHSS
KLRHPHLLQLMSVCLSSDLEKTRLVYERVNFGSLYSVLHERRTEFPVLRMETILHVLLQI
NDALRFLHSRGFIHRTVTSYAIQIVSSGEAKLCNMEYMIES-KDGGE--HSDLTRIPVPA
QLYKWCSPEVILEKSVTVKSDIYSFCAVMQEALT--ETLPWKGIEDSVIKQLIISGQQLE
ADVRLPVPYYD-IVKSGLESKQKNRSMNLQDIQYILKNDL----KDLTKSQSCHADEMAK
AQRPAVFADINICLSSTFSYQKRTLELNEKEI----------TEA-DSSAVP--RYPIFP
EEDNALVDLEAPTSLQLVAQENSHDA--------------A-----SETQMTCSV---SD
VDDSLCSFEMNEAFAS-CPDFHEDFLEEGAELSRTLKDKKRQ-QKEK-DENVLGDLFLSP
GMYCEE-KPV--Y-E-EG-----SISESVAECTTEEEEGKSEASDLNMLAQVRGDAGRRR
STLSSNE-HHLSKCVLNLKIVQSMLQQAAESLCRTEEKLNKLEAAEKQRS--D---NIYQ
-------N------INNPFSGANTFLWKAVGPPSSDYIPPLV------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---

--MSRAVHFPVPCPVLLGTLTDDSLEAQLHEYAKQGNYVKVKKILKKGVCVDAVNTLGQS
ALFVAALLGYVKLVDVLVDYGSDPNHRCFDGSTPVHAAAFSGNQWILSKVLT AGGDLRLH
DEKGRNPQAWALAAGKDRSTQ--MVEFMQ-RCASHMKAVI-QGFS-YDLLKKIDSPQRLI
GSPPWFGGLIQGSP---NSSPNRQ--PKPGIISAQNIYSFGFGK----------------
------------------------------------FYLTSG-MQLTYPGSLPVIGEKEV
IQADDEPTFSFFSGPYMVMTNLVWNRSRVTVKELNLP-THPHCSRLRL ADLLIAEQEHSS
NLRHPSLLQLMAVCLSRDLEKIRLVYERITVGTLFSVLHERRSQFPVLHMEMIVHLLLQI
ADALIYLHSRGFIHRSLSSYAVHIVSAGEARLTNLEYMMES-QDSGA--HRDMTRVPLPA
QLYNWAAPEVVLQKTATVKSDIYSFSMIIQEILT--DNIPWNGLDGSLVKETIALGNYLE
ADVRLPEPYYD-IVKSGIHAKQKNRTMNLQDIRYILKNDL----KEFIGAQKTQTTESPR
GQRYEPHPDINICLGLTSEYQKDPPDLDIKEL----------KET-GSQPHSPTDHSF-L
TEK--TLAPQTLDSSLSAQEPDNPNV--------------PSA--SRLAEEVRSP---TP
SEASLYSFEINEIYSG-CLTLGTDKEEECPGTASSPEGDKAN-QVDE-LPSLEEE-----
-LDKME-RELHCFCEEDK-----SFSDVDTDLSFEDGDWQSDSLSSLSLPEPTREAKGKT
SSWSKTD-EYVSKCVLNLKISQVMMQQSAEWLRKLEQEVDELEWAQKELDN-QCRSLWDA
-------S------LRFANTKF---L-SAVGPPSLTYLPPVMQLSEPKQP-ENGGNWLTL
ARPPGNERDFQE----GNFSKK-SEKLSACDWNPF---TQASEESRGYCSEPNNQPPTLC
GPGKQNTGEQLPSTEEAKESLERN-TNQ--------------------------------
--------------NIRR---IRMESVSSEVCDTKSR--------NNEDAGEARSKWRLA
VKEMAEKAVSGQLLVPPWNLQSSF--ESKV----ENESTPLPRPP--------------I
RGPESTDWQ---------YILEYQREKDELKGNM--KFGKMENSDCDKNKHS-SWTGLQR
FTSIIYPFFR------------NHERQSIMKP------LKTSCDTSVGT-----------
--------------------------EKF----------YSTSS--PI-EDDFERIQSSF
AQ------PQGYV-EENFQIREIF-GKNAEILTKPQFQAVQCAEDE----QEETLEET--
-PKELKEKNISLTDIQDLSSITYEQDGCFKETSCKTPKLKHAPTSASTPLSP---ESISS
AASHYEDCLEN-TFH-VKRGSTFCWNGQEAMRTLSTKFTTVR-ERAKSLESLLASSKTLP
AKLTDP--KRLCMFGGACSSNISTAFVT--------------STHSTKRKSLPGELAEAT
SQHHIDELPPPAQELLDEIEQLKQQQVSSMVSLE-----NTAHDLNV-T--ENDKKHLEE
----QETNSSKDSSF-LSSREIQD-LEDTERAHSSLDEDLERLLQLPEE-NMTLLDPTK-
GSTR-EKKTKDQDMVEQKRKKKEGIKPERRKSDSFL-GTL-------EE-DELKPCFWKR
LGWSE------P----------------SRIIVLDQSDLSD-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---

--MAHPIPLPFPCPVKLGSVKGDSLEAELHDYVREGNYVKVKKLLKKGIFVDAVNSMGQT
CLFAAALLGLGKIVDALLEYGSDANHRCYDGSTPVHAAAFSGSQGILSKLLDGGGELRVH
DREGRTPQVWALSARKESSAQM--LEFMQ-QCSLHMQAAL-WNLP-SDLLRRVGSSKALL
CSPSRLGALVQGNV---ENPLGKLKKLQGQPSVAKNIYSFGFGK----------------
------------------------------CIFLFQFHLASS-GHLGYLASLPIIGDKDV
VQADDEPAFSYPLGPYMIMTNLVWGGSRVTVKELSFQ-PQQSSWKLRLADLLLAEQEHSS
KLRHPHLLQLMSVCLSCDLEKTRLVYERVHFGSLYSILHERRAEFPVLQTETIVHVLLQI
LEALRFLHSRGFIHRSLSSFAIQIVSSGEGKLCNLEYMIQS-KDSGV--HSDLTRIPVPA
QLFRWSSPEIILGKPGTVKSDVYSFCAVLQEALT--ESLPWKGVEDSAVKQLILSGEQLE
ADVRLPLLYYD-VVKSGLEPKPRNRSMKLQDIQYILKNDL----KDLVKSES----GMPK
AQRSAVLADVNICWASAFRFQKRTVEFQEEEI----------SKA-GEFLGA--RCP---
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---

--MSRAVPLPIPCPVQIGTLRNDSLEAQLHEYVKQGNYVKVKKILKKGICVDAVNSLGQT
PLFVAALLGLMKLVDVLVDYGSDPNHRCFDGSTPVHAAAFSGNQWILSKLLDAGGDL RLH
DERGQNPQTWALTAGKERSTQ--IVEFMQ-RCASHMQAII-QGFS-YDLLKKIDSPQRLV
YSPPWFGGLGQRNP---NGSPKRL--LKAGVISAQNIYSFGFGK----------------
------------------------------AMPWFQFYLTGV-TQIAYLGSLPVIGEKEV
IQADDEPTFSFFSGPYMVMTNLVWNGNRVTVKELNLP-THPHCSKLRL ADLLIAEQEHSS
KLRHPYLLQLMAVCLPQDLKKTRLVYERIAIGTLFSVLHERRSQFPVLHMEVIVHLLLQI
SDALRYLHFRGFIHRSLSSYAIHIISPGEARLTNLEYMMES-QDGGV--QRDLTQVPLPT
QLYNWAAPEVILQKAATVKSDIYSFSMIVQEILT--DDIPWSGLNGSVIKEAIALGNYLE
ADVRLPKPYYD-IVKSGIHVKQKDRTMNLQDIQYILKNDL----KDFTGAQRTKPTERPR
VQRYGLHSDVNVYLGLTAEHPKETPDMEIKEL----------KEM-DSQPHSPRVHSL-F
TEG--TVDLQAPDACLLARETQNQDA--------------PCPA-PFMAEEASSP---ST
GQASLCSFEINEIFSG-CLTLEDVI-EEPPGTASSFEADRSN-QVDE-LKSMEEL-----
-MGKME-REACCFWSEDK-----SSSEAGTEHSFEDRDWQNGSLSSLSLPEPVREAMSNL
NKRSKTEEYYLSKCVLDLTITQKIMQENDDRLRNVEEILDEVEMKQKEQEE--HMSLWTA
-------S------SKFANVYN---LPLAVGPPSLSYIPPVLQPSGGQQL-DTSGNCPTL
VRFP---RT----------------------------------------------LPTLC
NPEKQNTDQQFQPTQGAKDSLERS-IIQNTSSQGRP-RESTAQAKATR-LNSA--LFTLS
SHQQGPSVSPSSHQDSTR---MSMEPVSSEIYNAESR--------N-KDDGEVHLKWKRE
VKEMAEKAATGQLTVSPWHPQSSLTLESEA----ENEPDALLQPP--------------I
RSPENMDWQ---------RVIEYHRENDEPRGNG--KFDKMGNSDCDSDQHG-RQPGPQS
FTSISHPSPG------------QNEQPEHSEA------FQASSDALVAVEKS----YSNE
STQSTCSPQSSE---DITDEFLTPDHEYFYSSAAQENLALETSS--PV-EEDFGGIQGAF
AQ------LQVSG-EEKFQMIKIL-GKNAEILPRSHFPPIRSTEDE----QEETLKES--
-PKELKEKDISLTDIQDLSSISCEPDSSFKEASCKTPKINHAPTSVSTPLSP---GSVSS
AASRYKDCLERMTLQ-VKTGSASSWNSQESIRTLSDEFTSVR-ERAKRLDSLLTSSETPP
SRLTGL--KRLSSFTGSGSPRLAKACDTS-------------LPHATQRRSLPK--VEAI
SQHHIDELPPPSQELLDEIELLKQQQSSSTVLHE-----NTASDAGV-T--ANDERHLEE
----QETDSKKEDSSMPWSKEAEDLGEDTERAHSTLDDDLERWLQPPEE-SMELQDLPK-
GSER-ETNTKDQEVGEEKRKREDSITPERRKSESVL-GTS-------EE-DELKPCFWKR
LGWSE------P----------------SRIIVLDQSDLSD-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---

--MSRTVHLQVPCPVQLGTLRNDSLEAQLHEYVKQGNYVKVKKILKKGTYVDAVNSLGQT
ALFVAALLGLKKLVDTLMDFGSDPNHRCFDGSTPVHAAAFSGNQWILS------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---

------------------------------------------------------------
------------------------------------------------------------
-----------------------MVEFMK-RCTSHMQAIM-QGFS-YDLLKKIDSPQRLI
CSTPCLAGLLQGSP---NGSPNRP--LKAGVISTQNIYSFGFGK----------------
------------------------------------FYLTGG-TQLAYLGSLPIIGEKEV
MQADDEPTFSFISGPHMVMTNLVWNGSRVTVKNLNLP-THPHSSRQRLADLLIAEQEHSS
KLRHPHLLQLMAVCLSQDLEKTRLVYERITVGTLFSVLHERRSEFPVLHMEVMVHLLLQI
ADALRYLHSRGFVHRSLSSYAVHIVSAGEARLTNLEYMLES-QDSGE--QKDLHQVPLPT
ELYNWAAPEVIFQKAATVKSDIYSFSMIIQEILT--DSVPWNDLDGSAIKEAILLGNYLD
ADVRLPKPYYD-VVRSGVQVKQKDRTMNLQDIQYVLKNDL----KENIGAQRTQPTESPR
VQRCEPYPDVSVYLGLTSEHPKAGADLEIKEL----------KES-GSQPHSPRGHSCPT
AKA--ALGPQPLNPSMMAQAPQNPDV--------------PPPP-APLVAETKSS---SA
SQDSLHSFEINEIYSG-CLNVGDNTEEEYPVGTLALEGDKPN-QADE-LPSLEEE-----
-LDKME-EEAH-LCDEDE-----SSSEADTEL-FGDWDWQNSSLSLLSLPEPTREAKGTV
SSWTKTE-EYISKCVLNLKISQTMAHEITDLVGTIEQKLDEVELIQKE-----HISLWTA
-------S------RLFPDVCD---LPRAVGPPTLNYVHPVMQVSGVPQP-DTNGHCPTL
SRSPRTMKELQG----GHFGKN-A-KRSSYGWKPF---TQVSEDSTEDQSE---------
--RHQDTGEPFQATQGAKDSLERK-NQD-----------------------------SRS
SHAQGPSGSSCPYQGSTR---INVESMSSVISNVKSE--------S-KDDGKIRLKWKTE
VKETAEKAASGELPVLPWHPQSSSILKSEV----AHGSSPLLQPP--------------T
RGPENMDWQ---------RGVQFRREKEEPGGND-VKLRKVDNCDHDSEKCG-RQPGPQN
FTSIRHLSPR------------KNEQPEPSEA------FQASSDMSETTEKS----YNDH
ATPSSCSPESSE---DRTDEFLTPDYEYFYSSAAQENLPLETSS--PI-EENFEGIQGTF
AQ------PQGYG-EEKFQMKKIL-EKNTEIFTR--FQSMQSTECE----QEETLKEP--
-PKELKEKDISLSDIQDLSSISYEPDGSFKEASCKTPQVRHAPTSVSTPLSP---E----
------------------------------------------------------------
-------------------------------------------------------LVEAI
SQHQIEDLPPPSQELLEEIEELKQQQASSMVLPHP---WRTARPPSI-T--ADDPKHLEE
----QETGSNKEDSSLLWIRESQDLGEDTERAHSTLDEDLERWLQPPEEKNMELQDPCK-
SFKR-DTKTKEEDIGEKKSKRKESIKPEIRKSESFL-GSC-------DE-DELKPCFWKR
LGWSE------P----------------SRIIVLDQSDLSD-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---

-----------------------------------------MIGRKQGIYVDAVNSLGQT
ALFVAALLGLRKFVDVLVDYGSDPNHRCFDGSTPVHAAAFSGNQWILSKLLDAGGDLRLH
DERGQNPKTWALTAGKERSTQ--IVEFMQ-RCASHMQAII-QGFS-YDLLKKIDSPQRLV
YSPPWFGGLVQGNP---NGSPNRL--LKAGVISAQNIYSFGFGK----------------
------------------------------------FYLTGA-TQMAYLGSLPVIGEKEV
IQADDEPTFSFFSGPYMVMTNLVWNGSRVTVKELNLP-THPHCSKLRLADLLIAEQEHSS
KLRHPYLLQLMAVCLSQDLEKTRLVYERITIGTLFSVLHERRSQFPVLHMEVIVHLLLQI
SDALRYLHFQGFIHRSLSSYAVHIISPGEARLTNLEYMLES-KDRGV--QRDLTRVPLPM
QLYNWAAPEVILQKAATVKSDIYSFSMIMQEILT--DDIPWNGLDGSVVKKAVVLGNYLE
ADVRLPKPYYD-IVKSGIHVKQKDRTMNLQDIRYILKNDL----KDFTGAQRTQPTEGPR
VQRYGLHPDVNVFLGLTSEHPGETPDMEIIEL----------KEM-GSQPHSPRVHSL-F
TEG--TLDPQAPDPCLMARETQNQDA--------------PCPA-PFMAEEASSP---ST
GQPSLCSFEINEIYSG-CLTLEDDI-EEPPGAASSLEADGPN-QVDE-LKSMEEE-----
-LDKME-REACCFCSEDE-----SSSKAETEYSFEDWDWQNGSLSSLSLPESTREAKSNL
NNRSVTEEYLISKCVLDLKIMQTIMQENDDRLRNIKQILDEVEMKQKEQEE--RMSLWAT
-------S------REFTNAYK---LPLAVGPPSLNYIPPVLQLSGGQQP-DTSGNYPTL
SRFPRM-------------------------------------------------LLTLC
DPGKQNTDEQFQCTQGAKDSLETS-RIQNTSSRGRP-RESTAQAKATQ-FNSA--LFTLS
GRPQGPSASPSCHWDSTR---MSVEPVSSEIYNAESR--------N-KDDGKVHLKWKME
VKEMAKKAATGQLTVPPWHPQSSLTLESEA----ENEPDALLQPP--------------I
RSPENTDWQ---------QVIEYHRENDEPRGNG--KFDKTGNNDCDSDQHG-RQPRPGS
FTSIRHPSPR------------QKEQPEHSEA------FQASSDTSVAIEKS----YSHQ
SMQSTCSPESSE---DITDEFLTPDDEYFYSSTAQENLALETLS--PI-EEDFEGIQGAF
AQ------PQVSG-EEKFQMRKIL-GKNAEILPRSQFQPIRSTEDE----QEETLKES--
-PKELKEKDISLTDIQDLSSISYEPDSSFKEASCKTPKINHAPTSVSTPLSP---GSVSS
AASQYKDCLESITFQ-VKTEFASCWNSQEFIQTLSDDFISVR-ERAKKLDSFLTSSETPP
SRLTGL--KRLSSFIGAGSPSLVKACDSS-------------PPHATQRRSLPK--VEVF
SQHHIDELPPPSQELLDEIELLKQQQGSSTVLHE-----NTASDAGG-T--ANDQRHLEE
----QETDSKKEDSSMLLSKETEDLGEDTERAHSTLDEDLERWLQPPEE-SMELQDLPK-
GSER-ETNIKDQEVGEEKRKREDSITPERRKSESVL-GTS-------EE-DELKSCFWKR
LGWSE------S----------------SRIIVLDQSDLSD-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---

--MSRAVHLPVPCPVQLGSLRNDSLEAQLHEYVKQGNYVKVKKILKKGIYVDAVNSLGQT
ALFIAALLGLTKLVDVLVDYGADPNHRCFDGSTPVHAAAFSGNQWILSKLLDAGGDLRLH
DEKGRNPQTWALAAGKERSTVM--VEFMQ-RCAAHMQAVI-QGFS--DLLKKIDSPQRLI
SGVPRFGGLMPGNS---NGSPNRP--LKAGVISSQNIYSFGFGK----------------
------------------------------------FYLTGG-TQLAYLGSLPVIGEKEV
IQADDEPTFSFFSGPYMAMTNLVWNGSRVTVKELHLS-THPHCSRLRLADLLIAEQEHSS
KLRHPHLLQLMAVCLSPDLEKTRLVYERVTVGTLFSVLHERRAQFPVLHMEVIVHLLLQI
SDALRYLHSRGFIHRSLSSYAIHIVSTGEARLANLEYMMES-QDGVA--HRGLTRVPLPT
QLYNWAAPEVILQKAATVKSDIYSFSVIVQEILT--DNIPWDGLDGSVIKETIVLGNYLE
ADVRLPKPYYD-IVKSGIQVKQKDRTMNLQDIRYIMKNDLK----DFIGAQRTQPTDSPR
VQRYEFHPDVSVCLGLTSEHPKETPNLEIKEL----------KETAGGQFHSPRGHSSPT
GK--ATPEPPVPDISPVAQQTHRQDA--------------ASPACSVA-EEARNP---SP
DRTSLCSFEINEIYSG-CLDTADDPEEEHPGTGSSLEGATPN-QTDE-LKSMEEE-----
-LEKME-REACCFCDEDE-----SSSDADTELSCEDWEWQKGALRSPSQPEPARGAQGTA
NNRSVTE-EYISKCVLSLKISQTLMHQNADLLRNVQQKIEKLEMIQKEQA--ERRSLWAS
-------S------REFAGIHD---SPSALGPPASSYLPPVVQRPGDQRP-DPGGSGLTL
ARSPRTVKDFRG----GHFGKR-SKKRSNCGWTPLASFPQVTEESTGDQLEKGRQLPTLC
GPGKQSRGEQFQPTHGAKDSLERD-RNQSTSSQGRP-RESSPQSRPTQ-LSSV--LLTEP
SHPQGPPASSNPGQDSTR---ISMQSVSSEIYNAKSR--------NNKDDGEIHLKWKME
VKEMAAKAATGQLTVPPWHPRSGVALDSKA----ENEPDPLPQLP--------------I
KVSEHVDWQ---------QAAEYLKKSDEPGGN--DACGQTDS----SDQHG-RQSGPQR
FTSIRHLPPR------------KDEQPEHGEV------FQANSDASVAVEKS----YSGQ
STQSTCSPESSEDTEDMTDEFLTPDHEYFYASIAQENLALETSS--PI-DEDFEGIQHAC
AQ------PQASG-EEKFQMRKNL-GKNAETLTKSQFQPIRSPEGE----QEETLKEP--
-PKEAKEKDISLTDIQDLSSISYEHDSSFKEVSCKTPKINHAPTSVSTPLSP---GSISS
VASQYKDCLGSIPFQDTKTGSASCWTSQESTQTLSDKFTSVR-EKAKSLDSLLTSSEIVP
ARLANL--KRLPAFTGAGSSSITKAPD-A-------------SCRATQRRSLPKELVEAI
SQHHIDELPPPSQELLDEIEHLKGQQVSSTALD-EN----TASRPGS-I--ANDQRHLEE
----QETHSSKEDSSMLWTKETQDLEEDTERAHSTLDEDLERWLQPPGD-STQLPDLPK-
GPAR-EASSKDQEVGEKKRKEEESTKPERRKSESFL-GTS-------EE-EELKPCFWKR
LGWSE------P----------------SRIIVLDQSDLSD-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---

--MSRAVRLSIPCPVRLGTLKNDSLEAQLHEYVKQGNYVKVKKILKKGICVDAVNSLGQT
ALFVAALLGLTKLVDVLVDYGSDPNHRCFDGSTPVHAAAFSGSQWILSKLLDAGGDL RLH
DEKGRNPHSWALAAGKDRSTPM--VEFMQ-RCTLHMQAIM-QGFS-HDLLKKIDSPQRLI
CSPPCLVGLLQGSP---NGSPKRP--LKAGVISTQNIYSFGFGK----------------
------------------------------------FYLTGG-TQLAYLGSLPIIGEKEV
IQADDEPTFSFISGPYMVMTNLVWNGS RVTVKSLNLP-THPHSDRLRLADLLIAEQEHSS
KLRHPHLLQLMAVCLSQDLEKTQLVYERITVGTLFSVLHERRSQFPVLHMEVMVLLLLQI
ADALRYLHSRGFVHRSLSSYAVHIVSAGEARLTNLEYMLES-QNSGG--HRNLSQVPLPT
ELYKWAAPEVIFQKAATVKSDIYSFSMIIQEILT--DDVPWNDLDGSVIKETLLLGNYLE
ADVRLPKPYYD-VVKSGIQVKQKDRTMNLQDIQYILKNDLK----ENTGGQRTQPMESPR
VQRREPYPDVSVYLGLTSERPKGSADLEIKEL----------KES-GSQLHSPKGHSSPT
AK--AALAPQTPDPSLMAQVPQNPD-------------APPPTATSVV-AQTSSP---NA
SQGSLHSFEINEIYSG-CLNIGDDTEEECPGATSALEGDKPD-QADE-LQSLEEE-----
-LDKIG-EE-AHLCDEDE-----SSSEVDTELFFGDWDWQNSSLSLLSLPEATGEAKGKV
SSWSKTE-EYISKCVLNLKISQTMAHEITDLVGNIEQKLDEVELIQKE-----HISSWTA
-------S------RLFPDVCD---LPIPVGPPTLNYIHPVTQVSGGSQL-DTNGNCPTL
LSSPRTVKEFQG----GHFGKK-PKRTSSYGWKPF---TQVSEESTKDQSERHQQLSTIC
DPGKQDRSEPFQATQGAKDSLERK-KNQDSS-QRKS-KESSTQGKVVE-LKSI--LFPMS
SRVQGPSGSSCPSQGSTR---MNVESMTSVIS-NVKP--------GNKDDGKIHLKWKTE
VKETAEKAASGELPVFPWHPQSSLTLKSEA----VPGSSPLLQPP--------------A
RGPENMDWQ---------RVVEFHREKEEPGGND-VKSGKVDNCDHDSEKRG-RQPGTQS
FTSIRHLSSR------------KNEQPEPSEA------FQASSDIAVTIEKS----YNDH
---ATCSPESSE---DITDEFLTPDHEYFYSSAAQENLPIETSS--PI-EENFEEIQGAF
AQ------PQGYG-EEKFQMKTVF-RKNAEIFT--RFQAMQSTECE----QEETLKEP--
-PKELKEKDISLTDIQDLSSISYEPDGSFKETLCKTPKVSHAPTSVSTPLSP--------
------------------------------------------------------------
----------------------------------------------------E--LMEAV
SQHQIEELPPPSQELLEEIEQLKQQQAASLVLQ-EN----TARHPGI-T--ADDPKHLEQ
----QETDSNKEDSGLLWTRESQDVGDDTERAHSTLDEDLERWLQPCEEKNIELHDSCK-
DFKR-DTKTKDQDFGEKKTKSKESIKSERRKSESFL-GTC-------EE-DELKPCFWKR
LGWSE------P----------------SRIIVLDQSDLSD-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---

--MSRAVHLPVPCPVQLGSLRNDSLEAQLHEYVKQGNYVKVKRILKKGIYVDAVNSLGQT
ALFIAALLGLTKLVDVLVDYGADPNHRCFDGSTPVHAAAFSGNQWILSKLLDAGGDLRLH
DEKGRNPQTWALAAGKERSTVM--VEFMQ-RCAAHMQAII-QGFS--DLLKKIDSPQRLI
SGVPRFGGLMQGNP---NGSPNRP--PKAGVISAQNIYSFGFGK----------------
------------------------------------FYLTGG-TQLAYLGSLPVIGEKEV
IQADDEPTFSFFSGPYMVMTNLVWNGSRVTVKELHLS-THPHCSRLRMADLLIAEQEHSS
KLRHPHVLQLMAVCLSPDLEKTRLVYERVTVGTLFSVLHERRAQFPVLHMEVIVHLLLQI
SDALRYLHSRGFIHRSLSSYAIHIVSTGEARLTNLEYMMES-QDGGA--HRGLTRVPLPT
QLYNWAAPEVIIQKAATVKSDIYSFSVIVQEILT--DNIPWDGLDGSVIKETIVLGNYLE
ADVRLPKPYYD-IVKSGLQVKQKDRTMNLQDIRYIMKNDLK----DFIGAQRTQPTESPR
VQRYEFHPDVNVCLGLTSEHPKETPNLEIKEL----------KET-GSQFHSPRGHSSPT
GK--ATPEPPVPDVSPVAQQTHRQDA--------------ASPACSVA-EEARNP---SP
DQTSLCSFEINEIYSG-CLDTADDPEEECPGTGSSLEGAIPN-QTDE-LKSMEEE-----
-LEKME-REVCCSCDEDE-----SSSDADTELSCEDWEWQNDALCSPSRPEPARGAKGAT
NNRSMTE-EYISKCVLNLKISQTLIHQNADLLRNVQQKIEKLEMIQKEQA--ERRSLWAS
-------S------REFAGIHD---SPSALGPPASSYLPPVVQRPGDQQL-DPGGSGLTL
ARSPR-------------------------------------------------TLPTLC
GPGKQSRGEQFQPTHGAKASLERD-RNQNTSSQGRP-RESSPQSKTTQ-LSSA--LLTVP
SHPQGSPTSSKPGQDSTR---ISMQSVSSEIYNAKSR--------NNKDDGEIHLKWKTE
VKEMAAKAATGQLTVPPWHPRSGVALDSEA----ENEPDPLPQLP--------------I
RVSEHMDWQ---------QAADYLKKSDEPGGN--DKCGQTDS----SDQRG-RQSGPQR
FTSIRHLPPR------------EDEQPEHSEV------FQANSDASVAVEKS----YSGQ
SAQSTCSPESSEDTEDMTDEFLTPDHEYFYSSIAQENLALETSS--PI-DEDFEGIQHAC
AR------PQASG-EEKFQMRKNL-GKNSEILTKSQFQPIRSPEGE----QDETLKEP--
-PKEVKEKDISLTDIQDLSSISCEHDGSFKEVSCKTPKINHAPTSVSTPLSP---GSLSS
VASQYKDCLESIPFQDTKTGSTSCGTSQESTQTLSDKFTSVR-EKAKSLDSLLTSSEVLP
ARLTNL--KRLPAFTGAGSSSIAKAPD-T-------------SRCATQRRSLPKELVEAI
SQHHIDELPPPSQELLDEIEHLKGQQVSSTALD-EN----TASRPGS-T--ENDQRHLEE
----QETHSNKEDSSMLWTKETQDLEEDTERAHSTLDEDLERWLQPPED-STQLPDLPK-
GPAR-EASSKDQEVGEKKRKGEESTKPEKRKPESFL-GTS-------EE-EELKPCFWKR
LGWSE------P----------------SRIIVLDQSDLSD-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---

--MSRAVRLPVPCPVQLGTLRNDSLEAQLHEYVKQGNYVKVKKILKKGIYVDAVNSLGQT
ALFVAALLGLRKFVDVLVDYGSDPNHRCFDGSTPVHAAAFSGNQWILSKLLDAGGDL RLH
DERGQNPKTWALTAGKERSTQ--IVEFMQ-RCASHMQAII-QGFS-YDLLKKIDSPQRLV
YSPSWCGGLVQGNP---NGSPNRL--LKAGVISAQNIYSFGFGK----------------
------------------------------------FYLTGA-TQMAYLGSLPVIGEKEV
IQADDEPTFSFFSGPYMVMTNLVWNGSRVTVKELNLP-THPHCSKLRL ADLLIAEQEHSS
KLRHPYLLQLMAVCLSQDLEKTRLVYERITIGTLFSVLHERRSQFPVLHMEVIVHLLLQI
SDALRYLHFQGFIHRSLSSYAVHIISPGEARLTNLEYMLES-EDRGV--QRDLTRVPLPT
QLYNWAAPEVILQKTATVKSDIYSFCMIMQEILT--DDIPWNGLDGSVVKKAVVLGNYLE
ADVRLPKPYYD-IVKSGIHVKQKDRTMNLQDIRYILKNDL----KDFTGAQRTQPTESPR
VQRYRLHPDVNVYLGLTSEHPRETPDMEIIEL----------KEM-GSQPHSPRVHSL-F
TEG--TLDPQAPDPCLMARETANQDA--------------PCPA-PFMAEEASSP---ST
GQPSLCSFEINEIYSG-CLILEDDI-EEPPGAASSLEADGPN-QVDE-LKSMEEE-----
-LDKME-REACCFGSEDE-----SSSKAETEYSFDDWDWQNGSLSSLSLPESTREAKSNL
NNMSTTEEYLISKCVLDLKIMQTIMHENDDRLRNIEQILDEVEMKQKEQEE--RMSLWAT
-------S------REFINAYK---LPLAVGPPSLNYIPPVLQLSGGQQQ-DTSGNYPTL
PRFPRM-------------------------------------------------LPTLC
DPGKQNTDEQFQCTQGAKDSLETS-RIQNTSSQGRP-RESTAQAKATQ-FNSA--LFTLS
SHRQGPSASPSCHWDSTR---MSVEPVSSEIYNAESR--------N-KDDGKVHLKWKME
VKEMAKKAATGQLTVPPWHPQSSLTLESEA----ENEPDALLQPP--------------I
RSPENTDWQ---------RVIEYHRENDEPRGNG--KFDKTGNNDCDSDQHG-RQPRPGS
FTSIRHPSPR------------QKEQPEHSEA------FQASSDTLVAVEKS----YSHQ
SMQSTCSPESSE---DITDEFLTPDDEYFYSSTAQENLALETSS--PI-EEDFEGIQGAF
AQ------PQVSG-EEKFQMRKIL-GKNAEILPRSQFQPVRSTEDE----QEETSKES--
-PKELKEKDISLTDIQDLSSISYEPDSSFKEASCKTPKINHAPTSVSTPLSP---GSVSS
AASQYKDCLESITFQ-VKTEFASCWNSQEFIQTLSDDFISVR-ERAKKLDSLLTSSETPP
SRLTGL--KRLSSFIGTGSPSLVKACDSS-------------PPHATQRRSLPK--VEAF
SQHHIDELPPPSQELLDEIELLKQQQGSSMVLHE-----NTASDAGG-T--ANDQRHLEE
----QETDSKKEDSSMLLSKETEDLGEDTERAHSTLDEDLERWLQPPEE-SVELQDLPK-
GSER-ETNIKDQKVGEEKRKREDSITPERRKSEGVL-GTS-------EE-DELKSCFWKR
LGWSE------S----------------SRIIVLDQSDLSD-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---

MMLLYSSSPRLPCRM--GALCCTLSPAP-----WNAGALPWTSIVP--ISLPSRCFDGST
PVHAAAFSGNQWILSKLLDAG--GDLRCFDGSTPVHAAAFSGNQWILSKLLDAGGDLRLH
DERGQNPKTWALTAGKERSTQIRVVEFMQ-RCASHMQAIS-QGFS-YDLLKKIDSPQRLV
YSPPWCGGLVQGNP---NGSPNRL--LKAGVISAQNIYSFGFGK----------------
------------------------------AMPWFQFYLTGA-TQMAYLGSLPVIGEKEV
IQADDEPTFSFFSGPYMVMTNLVWNGSRVTVKELNLP-THPHCSKLRLADLLIAEQEHSS
KLRHPYLLQLMAVCLSQDLEKTRLVYERITIGTLFSVLHERQSQFPVLHMEVIVHLLLQI
SDALRYLHFQVFIHCPLSFYAVHIISPGEARLTNLEYMLES-EDRGV--QRDLTRVPLPT
QLYNWAAPEVILQKAATVKSDIYSFSMIMQEILT--DDIPWNGLDGSVVKKAVVSGNYLE
ADVRLPKPYYD-IVKSGIHVKQKDRTMNLQDIRYILKNDL----KDFTGAQRTQPTESPR
VQRYGLHPDVNVCLGLTSEHPRETPDMEIIEL----------KEM-GSQPHSPRVHSL-F
TEG--TLDPQAPDPCLMARETQNQDA--------------PCPA-PFMAEEASSP---ST
GQPSLCSFEINEIYSG-CLILEDDI-EEPPGAASSLEADGPN-QVGE-LKSMEEE-----
-LDKME-REACCFGSEDE-----SSSKAETEYSFDDWDWQNGSLSSLSLPESTREAKSNL
NNMSTTEEYLISKCVLDLKIMQTIMHENDDRLRIIEQILDEVEMKQKEQEE--RMSLWAT
-------S------REFTNAYK---LPLAVGPPSLNYIPPVLQLSGGQQP-DASGNYSTL
PRFPRMLL-------------------------------------------------TLS
DPGKQNTDEQFQCTQGAKDSLERS-RIQNTSRW----------------FNIL--LFLM-
---------SLCHTDFCV---MSVEPVSSEIYNAESR--------N-KDDGKVHLKWKME
VKEMAKKAATGQLTVPPWHPQSSLTLESEA----ENEPDALLQPP--------------I
KSPENTDWQ---------RVIEYHRENDEPRGNG--KFDKTGNSDCDSDQHG-RQPRPGS
FTSIRHLSPR------------QKEQPEHNEA------FQASSDTLVAVEKS----YSHQ
SMQSTCSPESSE---DITDEFLTPDDEYFYSSTAQENLALETSS--PI-EEDFEGIQGAF
AQ------PQVSG-EEKFQMRKIL-GKNAEILPRSQFQPVRSTEDE----QEETSKES--
-PKELKEKDISLTDIQDLSSISYEPDSSFKEASCKTPKINHAPTSVSTPLSP---GSVSS
AASQYKDCLESITFQ-VKTEFASCWNSQEFIQTLSDGFISVR-ERAKKLDSLLTSSETPP
SRLTGL--KRLSSFIGAGSPSLVKACDSS-------------PPHATQRRSLPK--VEAF
SQHHIDELPPPSQELLDEIELLKQQQGSSTVLHE-----NTASDAGG-T--ANDQRHLEE
----QETDSKKEDSSMLLSKETEDLGEDTERAHSTLDEDLERWLQPPEE-SVELQDLPK-
GSER-ETNIKDQKVGEEKRKREDSITPERRKSEGVL-GTS-------EE-DELKSCFWKR
LGWSE------S----------------SRIIVLDQSDLSD-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---

--MSRAVHLPVPCPVQLGSLRNDSLEAQLHEYVKQGNYVKVKKILKKGIYVDAVNSLGQT
ALFVAALLGLSKLVDVLVDYGSDPNHRCFDGSTPVHAAAFSGNQWILSKLLDAGGDLRL H
DERGRNPQTWALTAGKEHSTAM--VEFMQ-RCASHMQAII-QGFS-YDLLKKIDSPQRLI
CSLPRFGGLIQGNP---NGSPNRL--LKAGVISAQNIYSFGFGK----------------
------------------------------AVLSFQFYLMGG-AQLAYLGSLPVIGEKEV
IQADDEPTFSFFSGPYMVMTNLVWNGSRVTVKELNLP-THPHCSRLRL ADLLIAEQEHSS
KLRHPHLLQLMAVCLSQDLEKTRLVYERITVGTLFSVLHERRSQFPVLHMEVIVHLLLQI
SDALRYLHSRGFIHRSLSSYAIHIISTGEARLTNLEYMMES-QDGRI--HRDLTRVPLPI
QLYNWAAPEVILQKAATAKSDIYSFSMIIQEILTA-DNIPWNGLDGSVIKEAIVLGKYLE
ADVRLPKPYYD-IVKSGIQVKQKDRTMNLQDIRYILKNDLK----DFLGTQRTQPTESPK
VQRYELHPDVNVYLGLTSEHLKETPNLEIKEL----------KEM-GSRLQSPRGPSSPT
GK--AAPDPRVLGPSMMAKETQNQDT--------------ASPACSVV-EEARSP---SP
GQTSLCSFEINEIYSG-CLDRGNDKEEEPPGDGSSFEDAGPS-QADE-LKSMEEE-----
-LEKME-REACCFCDEDE-----SSSEAGTELSFEDWDWQNDSLSSPSLLE---AATGSV
GNRRLTE-EYISKCVLNLKISQTVMHQNAHLLRNIQQKIDKLEMIQKEQE--ECRSLWAS
-------S------REFANIYD---FPSAVGPPASSYVPPVMQLSGGQWL-GTSGNCLTL
TRPS--------------------------------------------------ILPTFC
GPGKQSPCEQSQPTQGAKHSLERN-RSPNTSSQICP-FQSSARTRLTQ-FNSA--LVTVS
SHPKGPLLLAIPDQGSMR---MSLESVSSEICNVRLR--------NNEDDGNVHLKWKME
VKEMAERAATGQLMVPPWHPQSSMTLEGEA----KNEPDSLLQLP--------------M
RDPEKLGWQ---------CTVEYPRKNDEPGGN--GKCDKMDNGDCDRDQHG-RQPGPQS
YISNRHLSLR------------KNEQPEHSEV------FQASSDASVVIEKS----YSDQ
SMRSTCSPESSE---DITDEFLTPEHEYFYSSTAEENLALETSS--PI-EEDFEGIQDVF
AQ------PPGSGSEENFQMRKNL-GRNAEILTRSQFQPIQSTEGE----QEETLKES--
-PKELKDKDISLTDIQDLSSISCEQDSSFKKVSCKTPKVNHAPTSVSTPLSP--AGSSSS
PASGYKDCLENITFQ-IKTGSTSCWNSQESVQTSSDRFTTVR-EKAKSLDSFLTSSETIP
SKLTSL--KRWSAFTGASSSSIAKLPD-T-------------SSHATQ-RSLPKALVEAI
SQRHIDELPPPSQELLDEIEHLKQQ-ATSTMLG-EN----TASHLGI-T--ANDERHLED
----QEANSKKEDSSMLWTRETQDLGEDTERAHSTLDEDLERWLQPPED-SKELQDLPT-
GSTR-EANIKDQEAGEKKRKGEEKIKSERGKSDSFL-GTS-------EE-EELKPCFWKR
LGWSE------P----------------SRIIVLDQSDLSD-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---

-MMSRAVHLPVPCPVQLGSLRNDSLEAQLHEYVKQGNYMKVKKILKKGIYVDAVNSLGQT
ALFIAALLGLTKVVDVLVDYGSDPNHRCFDGSTPVHAAAFSGNQWILSKLLDAGGDLRLH
DEKGRNPQTWALTSGKERSTAM--VEFMQ-RCASHMQAII-QGFS-CDLLKKIDSPQRLI
CGPSRFGGLIQGNP---NGSPNRL--LKAGVISAQNIYSFGFGK----------------
------------------------------------FYLTGG-AQLAYLGSLPVIGEKEV
IQADDEPTFSFFSGPYMVMTNLVWNGSRVTVKELNLP-THPHCSRLRLADLLIAEQEHSS
KLRHPHLLQLMAVCLSQDLEKTRLVYERVTVGTLFSVLHERRSQFPVLHMEVIVHLLLQI
SDALRYLHSRGFIHRSLSSYAIHIVSTGEARLTNLEYMMES-QDGRI--HKDLTGVPLPT
QLYNWAAPEVILQKAATVKSDVYSFSVIIQEILT--DNIPWNDLDGSVIKEAIVLGNYLE
ADVRLPKPYYD-IVKSGIQVKQKNRTMNLQDIRYLLKNDLK----DFLGTQRTPPTESPT
VQRYELHPDVNVYLGLTSDQLKETPNLEIKEL----------KET-GSRLHSPRGPPSSP
EK--ATPDPQVLDPSMMTKEIQNQDT--------------ASPAGPVA-EEARSP---SP
GQASLCSFEINEIYSG-CLDRGDGKEE-PPEAGLSFEGAGPS-QADE-LKSMEEE-----
-LEIME-REACCFCEEDE-----SSSGASTELSFEDWDWQNGSLSSPSLPEPTRGAKDHV
SNRCVTE-EYISKCVLNLKISQTLMHQNADLLRNIQQKIDKLEMIQKEQE--ECRSLWAS
-------S------REFANIYD---SRSALGPPASSYIPPVIQLPGGQQL-DTSGNCLTL
TRSS-IVRDFQG----GHFGKR-SRKRSGCDRKAV---TQVSEESTGDQSEKSHQLPTFC
GPGKQSTSEQSQPAQGAKHSLERN-RSPNTSSQGRP-KESSAQTRLTQ-LSSA--LVTVS
RHSKGPAVSSSPSQGSTR---ISMESVSSEICNAKSR--------NNEDDGEVHLKWKME
VKEMAERVATGQLAVPPWHPQSGVSLEDEA----KNEPDLLLQPL--------------L
RDPEKVGWQ---------CTVEYPRKNEESGGN--GKCDKMDNSDCDSNQHR-RQHGPRS
FTNIRHLSPR------------KNEQPEHSEA------FQASSDAPVVIEKS----YSDQ
SVRSTCSPESSE---DITDEFLTPDHEYFYCSTAQENLALETSS--PI-EEDFEGVRDAF
AQ------PPSSG-EEKFQMRKRP-GRNAEILDRSQFQPIRSSEGE----QEETLKES--
-PEQLKEKDISLTDIQDLSSISYEQGGSFKEVSCKTPRINHAPTSVSTPLSP---GSSSS
AASQYKDCLESITFQ-IKTGSTSCWNSQESIQTSSDTFSTVR-EKAKSLDSFLTSSETVP
SRLTDL--KRLSAFTGAGSSSIAKSPD-I-------------SSHATQRRSLPKALVEAI
SQRHIDELPPPSQELLDEIEHLKKQQASSRVLG-EN----SASHLGI-T--AKDQRHLEE
----QETNCEKEDSSMLWTKETQDLEEDTERAHSTLDEDLERWLQPPED-NTGLQDLPE-
GSTR-EENIKDQEAGEKKRKGEERVKSERRKSDSFL-GTS-------EE-EELKPCFWKR
LGWSE------P----------------SRIIVLDQSDLSD-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---

--MSRAIHLPVPCPVQLGTLRNDSLEAQLHEYVRQGNYVKVKKILKKGIHVDAVNSLGQT
ALFVAALLGLTKLVDVLVDYGSDPNHRCFDGSTPVHAAAFSGNQWILSKLLDAGGDLRLH
DQKGRNPQTWALTAGKERSTPM--VEFMQ-RCASHMQAII-QGFS-YDLLKKIDSPQRLI
CSPPWFGGLMQGNS---NGSPNRL--LKAGVISAQNIYSFGFGKG---------------
-------------------------------CALFQFYLTGG-TQLAYLGSLPVIGEKEV
IQADDEPTSSFFSGPYMVMTNLVWNGSRVTVKELNLP-THPHCSRLRLADLLIAEQEHSS
KLRHPHLLQLMAVCLSQDLEQTRLVYERVTVGTLFSVLHERRSQFPVLHMEVIVHLLLQV
SDALRYLHSRGFIHRSLSSYAVHIVSTGEARLTNLEYMMES-RDGGV--HRDLTRVPLPT
QLYTWAAPEVILQKAATVKSDIYSFSMIVQEILT--DNIPWNGLDGSVIKEAIVLGNYLE
ADVRLPKPYYD-IVKSGIQVKQKDRTMNLQDIRYILKNDLK----DFIGAQRTQPTEDPR
VQRYKLHPDVSVYLGLTSEHPKEIPDLEIKEL----------KETAGSQPHSPRSPFSPI
EK--GVLNPQPPGPNLAAKDTQNQDI---------------SSDPFVA-EEASSP---SL
GQASLCSFEINEIYSG-CLNLGDDKEEELPGAPSSLEGNRPN-QADE-LKSMEEE-----
-LDKME-REACCFCDEDE-----SSSEADTELSFEDWDQQNGSFSSLSLPEPTREVKGNV
NNRSMTE-EYISKCVLNLKIAQTLMHQNASLLKNTQQKINKLEMIQKEQE--EHRSFWAT
-------S------REFVNVYN---LPSALGPPASSYIPPVVQQSGGQQP-DIRVNCPTL
ERFPR-------------------------------------------------TLLTLC
GPGKQNTGKQFQPSQEAKDSLERS-RNQHTSRQPRP-NLSTALAKKRK-FPKNIFFSTVS
SHQQGLGRSPSPQQDATRTNRISVESMSSQIYNTKSR--------NNEDDGAVHLRWKME
VKEIAEKVATGQLTVPPWHLQSSLTLDNEA----ENGPDPLLKPP--------------V
RGPKNMDWQ---------QVIEYHKENDEPGRN--GKFDNMHNSDHESDLHG-RQPGPQN
FTSIRQPSPG------------KNEQLEHSED------FQASSDA-VVTEKS----YSDQ
SVQSTCSPESSE---DITDEFLTPDHEYFYSSPTQENLVLETSS--PI-EEDFEGIQGAY
AQ------PQASG-KEKFQVTKIL-EKNAEILNRSHFQPIRSTEGE----QEEILKES--
-PKELKEKDISLIDIQDLSSISYERDSSFKEVSCKTPKTNHAPTSVSTPLSP--AGSISS
AASQYKDCLESITFQ-VKTQSTSWKNSQESIQTLSDKSVAVQ-EKAKNLDSLLTSSETLP
SRLTDL--KRLSAFTGAGSSSIANASD-I-------------TPHAIQRRSLPKELVEAI
SQHHVDELPPPCQELLDEIEHLKQQQASSKVLH-EN----TAGDPGL-S--ANDKSHLEE
----QETNGNKEESSILWTKEAQDLGEDTERAHSSLDEDLERWLQPPEE-TLELQDLPK-
GSTR-EINTKDQEVGEKKRKREESIKPERRKSESFL-GTS-------EE-DELKPCFWKR
LGWSE------P----------------SRIIVLDQSDLSD-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---

--MSRPVHLPVPCPVQLGTLRNDSLEAQLHEYIKQGNYVKVKKILKKGIYVDAVNSLGQT
ALFVAALLGLTKLVDVLVDYGSDPNHRCFDGSTPVHAAAFSGNQWILSKLLDAGGDL RLH
DEKGRNPQTWALTAGKERSTPM--VEFMQ-RCASHMQAVI-QGFS-YDLLKKIDAPQRLI
YSPPWFGGLMQGNL---NGSPNRL--LKAGVVSAQNIYSFGFGK----------------
------------------------------SMFWFQFYLTGG-TELAYLGSLPIIGEKEV
IQADDEPTFSFFSGPYIVMTNLVWNGSRVTVKELDLP-THPHCSKLRL TDLLIAEQEHSS
KLRHPYLLQLMAVCLSPDLEKTRLVYERVTVGTLFSVLHERRSQFPVLHMEVIVHLLLQI
ADALRYLHSRGFIHRSLSSYAIHIVSKGEARLTNLEYMMES-QDRGV--HRELTRVPLPT
QLYNWAAPEVILQKAATVKSDIYSFSMIIQEILT--DNIPWDGLDGSVIKEAIVLGNYLE
ADVRLPKPYYD-IVKSGIQVKQKDRTINLQDIRYILKNDLQ----DFIGDQRTQPTESPR
VQRYGFHPDVNVYLGLASEHPKETPDLEIIEL----------KET-GSQPHSPRSHFSPT
EK--GTLDAQTPNPSRIAKETQNQNT--------------PSPAPSVA-EVASSL---SA
GQASFCSFEINEVYSG-CLSIGDDKEEEPIRTSSSLEGDRPN-QADD-LKSMEEE-----
-LDKME-REAYSLCDEDE-----SFSESDTELSFENWDWQNGSLSSLSLPERTRQAKGNM
SNRSMTE-EYISKCVLNLKISQTLMHQNADLLRNIELKIEKLEMIQKEQE--EHMSLWAT
-------S------REFANVYD---LPSALGPPASSYIPPVLPLSAGQQS-DTSDSCPTL
ARFPR-------------------------------------------------TLPTLC
GPGKQNTSEQFQPTQGAKDSLERS-RNRNTCSQGRP-RESCAQAKVTK-LNST--VFPVS
SHQQGPPESPSPYQDSTR---TSMESVSSEIYNAKSR--------NNGDNGKLSLKWKME
VKEMAEKAATGQLIVPSWHPQSSLTLESAT----ENEPDSLLQPP--------------I
RGPENIDGP---------QVVEHHRENDKPGRN--GRCDEMDNRDCDHDQHG-RQPGPQS
FTSIKHPSPR------------TSEQPEHSED------FQAISDASVVIEKS----YSDQ
SMLSTCSPESSE---DITDEFLTPDHEYFCSLAAQENLALETSS--PI-EEDFEGKEGVF
PQ------LQASG-EGKFQMRKII-GKNAEILTWSQFQPTGSTKGE----HEETLKET--
-PKELKEKDISLTDIQDLSSISFEQDSSFKEASCKTPKINHAPTSVSTPLSP---GSISS
AASSYKDCLESVTFQ-VKTESTSCWNTQESIQSLSNKFTTVR-EIAKSLDSLFTSSENPP
LRQTDL--KRLSAFNVTGSSNITKASV-T-------------SPHATQRRSLP--KVEAI
SQHHIDDLPPPSQELLDEIELLKHQQTSSTVLH-ES----T-CELGI-T--ANDQRHLEK
----QETDSKKEDDSMLWTKEAQDLGEDTERAHSTLDEDLERWLQPPEE-SMEQQDLLK-
SSAR-KTKTGDQEVGERKRKGEESIKPERRKAESFL-GTS-------ED-DELKPCFWKR
LGWSE------P----------------SRIIVLDQSDLSD-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---

--MSRAVQLPIPCPVQLGTVRSDSIEAQLHECVQQGNYIKVKKILKKRVHVDSVNSLGQT
ALFTAALLGLPKVVDVLLDHGADPNRRCSDGSSPVHAAAFSAHQGILSKLLDAGGDLRLH
DENGRTPHAWALSAAKDQSAQV--LELLE-RCAAQTQALV-RGFP-RDLLRRVDCPQRLV
CPQSRFAGIVQGKPRNPDSSENRS--LHSGFVASKTIYSFGFGK----------------
------------------------------------FYFPGATTQPAFLSSVPVIGEKDV
VQAEDESTFTFASGPHMTMTNLMWSGTRVTVKELNLS-THPNCSKLRLADLLIAEQEYSS
KLRHPHLLQLMAVCLSHDLDRTRLVYERVNIGTLYSILHERRSQFPALQMEVILHLLLQM
NDALRYLHTRGLIHRSLSSYAIHIVSMSEARLTNLEHAIES-EDGRG--PRDPTGIPLPT
QLFNWAAPEVILQEAATVKSDIYSFCVIVQESLT--ESLPWNGVEGSVVKEAVVLGNHLE
ADVRLAQPYYD-IVKTGTRAKPKDRSMNLQDIRYLLKNDLQ----DLIESQKIHSAESSN
LQRCEIHL------RSTSIKQKEVLRLQVEAM----------KGL-GPRPNSPSRQSALT
EE--AVLCHDGMSGSRTT---------------------PRSQDASSEPERACGA---SL
EDESLRSFEINEVFSR-YLENQEEDSEGFSQSDRSRG-DDENGAGDGDAASAGGP-----
-TDTS--R-------GDPVSEGESES----ESAPEEAERRSPLAEPSGTWGTEGGARGGG
AEKSRME-QYISKSILNLKISQALVHQATDSLRNTEWKIDRLAAVQKHTELLRSVSQSA-
-------P------GRGGPRRGPSRLPEAVGPPTPEYDPPAVPSPAGRAD-PSR-SPPKA
AGQRRAARGVR----LGRFGQR-SGR--------------VPEEASGERSDRVKWEKR--
-----REGGKRWPLPGTPSPP-PS-TGPQLSPALRPFRHPLLRE----------------
--------------TFPVGQLPTVEFLPSEVYDSRIR--------SA-RDTEPQSKWTRE
VKEMAEKAACGQLGILPRYRPGDSTSESEM----EPDTEAERQPA--------------S
RAQDWADWW---------WR--GPRRDRRNGGRDEGGASEAD---TE-EEDEFKRPAELT
FLGPRPQSPR------------KYESADLRAA------FQESCGRSADTDKL----SSYS
K--------------SF--------------------------------TDPFKGINDFF
RIIRL---------DRKFLFPTFFERYNSDPMTKLQPPAVTSFEGK----REETPKEEWL
KERKEKEKEISFTDIQDLSSISDERDHLPKETPCKTPRTSHAPTSVSTPLSPE-------
------------------------------------------------------------
-------------------------------------------------------GTDAS
AGHYFDDLPPPSQELLDEIGKGS-------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---

--MSQAVPLPVPCPVQLGTLRNDSLEAQLHQYVKQGNYVKVKKILKKGIYVDAVNSLGQT
ALFVAALLGLRKFVDVLVNYGSDPNHRCFDGSTPVHAAAFSGNQWILSKLLDAGGDL RLH
DERGQNPKTWALTAGKERSTQ--IVEFMQ-RCASHMQAII-QGFS-YDLLKKIDSPQRLV
YSPPWFGGLVQGNP---NGSPNQL--LKAGVISAQNIYSFGFGK----------------
------------------------------AMPWFQFYLTGV-TQMAYLGSLPVIGEKEV
IQADDEPTFSFFSSPYMVMTNLVWNGSRVTVKELNLP-THPHCSKLRL ADLLIAEQEHSS
KLRHPYLLQLMAVCLSQDLEKTRLVYERVTIGTLFSVLHERRSQFPVLHMEVIVHLLLQI
SDALRYLHFQGFIHRSLSSYAVHIISPGEARLTNLEYMLES-KDGGV--QRDLTRVPLPM
QLYNWAAPEVILQKAATVKSDIYSFSMIMQEILT--DDIPWNGLDGSVVKKAVVLGNYLE
ADVRLPKPYYD-IVKSGIHVKQKDRTMNLQDIRYFLKNDL----KDFTGAQRTQPTESPR
VQRYGLYPDVNVYLGLTSEHPRETPDMEIIEL----------KEM-GSQPHSPRVHSL-F
TEG--TLDPQAPDPCLMARETQNQDA--------------PCPA-PFMAEEASSP---ST
GQPSLCSFEINEIYSG-SLTLEDDI-EEPPGAASSLEADGPN-QVDE-LKSMEEE-----
-LNKME-REACCFCSEDE-----SSSKAETEYSFEDWDWQSGSLSSLSLPESIREAKSNL
KNRSRAEEYLISKCVLDLKIMQTIMHENDDRLRNIEQILDEVEMKQKEQEE--RMSLWTT
-------S------REFTNAYK---LPLAVGPPSLNYIPPILQLSGGQQP-DTSGNCPTL
PRFPRM-------------------------------------------------LPTLC
DPGKQSTDEQFQCTQGAKDSLERS-RIQNTSSQGRP-RESTAQAKATQ-FNSA--LFTLS
SHRQGPSASPSCHWDSTR---MSVEPVSSEIYNAESR--------N-KDDGKVHLKWKME
VKEMAKKAATGQLTIPPWHPQSSLTLESEA----ENEPDALLQPP--------------I
RSPENTDWQ---------RVIEYHRENDEPRGNG--KFDKMGNNDCDSDQRG-RQPRPGS
FISIRHPSPR------------QKDQPEPSEA------FQASSDTLVAVEKP----YSHQ
SMQSTCSPESSE---DTTDEFLTPDDEYFYSSTAQENLALETSS--SI-EEDFEGIQGAF
AQ------PQVSG-EEKFQMRKTL-GKNAEILPRSQFQPIRSTEDE----QEETSKES--
-PKELKEKDISLTDIQDLSSISYESDSSFKEASCKTPKINHAPTSVSTPLSP---GSVSS
AASQYKDCLESITFQ-VKTEFASCWNSQEFIHTLSDDFISVR-ERAKKLDSLLTSSETPP
SRLTGL--KRLSSFIGAGSPSLVKACDSS-------------PPHATQRRSLPK--VEAF
SQHHIDELPPPSQELLDEIELLKQQQGSSTVLHE-----NTASDAGG-T--ANDQRHLEE
----QETDSKKEDSSMLLSKETEDLGEDTERAHSTLDEDLKRWLQPPEE-SMELQDLPK-
GSER-ETNIKDQEVGEEKRKREDSITPERRKSESVL-GTS-------EE-DELKPCFWKR
LGWSS------S----------------CRIIVLDQSDLSD-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---

-----------------------------------------------GIYVDTVNSLGQT
ALFTAALLGLPKLVDVLVDYGSDPNHRCFDGSTPVHAAAFSGNQWILSKLLDAGGDLRLH
DEDGKNPQSWALSSGKERSTAM--VEFMH-RCASHMQAII-QGFS-YDLLKRIDSPQRLI
CSPSRFGSLMHGNP---DNSPNRL--LKPGVVSSKNIYSFGFGK----------------
------------------------------GKFWFQFYLTGG-TQLAYLGSLPVIGEKEV
IQADDEPTFSFFSGPYMIMTNLMWNGSRVTVKELNFA-THQNCSKLRFADLLIAEQEHIL
SLYHLNFMWVSLTCSSCEQIGTAPSKKALVWRCLSDVYGSERSQFPVLHMEVIVHLLLQI
NDALRYLHSRGFVHRSLSSYAVHIVSAGEARLTNLEYMIES-QDGSV--HKDLTRVPIPN
VLYSWSAPEVILQKGATVKSDIYSFCIIIQEILT--DTLPWNGLEGSVIKESIVLGNHLE
ADARLPKTYYD-IVKTGIQVKQKDRTMNLQDIRYILKNDLK----DLIEAQRTHPVENSS
VERCKKHPDINIYLGMTSESQREALDLEVREL----------KET-GCQPDSPQHHSALP
EK--AALDGEVLNRSMTAKEMESHDTAS-------------------ELARACSP---SC
GDESLCSFEINEIYSC-YLDMCDDDLGEITSDISLGDGK--N-RGER-VKSMTGE-----
-SPERD-KGAL-FDYDDI-----TASEVGMESSSEQWQPLSDTFSS-HIEEVSKETKPDV
SSKSRTE-QYISKCVLNLKISQTLMQQVTESLQNAEQKIVKLEAVRKQQE---QHISWPV
-------L------RLSARGHDASAMWVAIGPPANRYIPPSLQIPVE-QP-SCVDRFQNL
VKTIR-------------------------------------------------ATSSFC
GANRQNINIKSQYPQGDDKILESTTRNQDISPQTCP-LNPCSQAVAFPRYQKNVFFFLKN
NTS-----------IIPHSFRMNAESISSEFCNPKTR--------ND-DSIEARLKWTTE
VKEMAEKAASGQLGSLLWYPLNNHTSDSETENDFE----SMQQS---------------P
RESQSTDCH---------Q-TDPLRDQDDPGRK--DQCEKTIHNDSESEDSE-GETRFQN
LTGTRHNLPR------------KKKQPDNGGA------FQKNSNSPEGIEKL----SSEH
SMESLYSVDSSE---DVTDEFLTPDHDYFYTPAVQEHLEVKMTV--KSQELNVKKINLCT
DNPVIVHFFFLSGREKFQVIEKIL-GNKSECMTELQFTPIRLEFF-----REEETKEP--
-SKELKEEDISLIDIQELSSISWGKGGSCKEIPCKTPKTSHGPTNVSTPLSP--IGAASS
SISLYKDYSSQ-----PKVQETSCWDSQESIRTMSNTFTTASGKKGWTTNSLSFPSEMPS
FGLTTPVSNRIMYFLGRIAPAMLKMLD-S-------------KPLHT----MTRVIADSS
SPDCIDELPPPSQELLDEIEHLKQQSASSSVLGENR-----SSSC-DLT--LNDQRHLEE
----KIIENKGEDGSILWTKETLYLTEETDRAHSTLDEDLERWLQPSEKSKEFQEGLTE-
SSAR-ETSITDQEVGDKKKKGGERAKAERRKPDSFS-GSP-------EDQEELKPGLWHR
LGWSQ------P----------------SRIIVLDQSNTSD-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---

--MSRAVPLPIPCPVQIGTLRNDSLEAQLHEYVKQGNYVKVKKILKKGICVDAVNSLGQT
PLFVAALLGLMKLVDVLVDYGSDPNHRCFDGSTPVHAAAFSGNQWILSKLLDAGGDL RLH
DERGQNPQTWALTAGKERSTQ--IVEFMQ-SCASHMQAII-QGFS-YDLLKKIDSPQRLV
YSPPWLGGLVQRNP---NGSPKRL--LKAGVISAQNIYSFGFGK----------------
------------------------------AMPWFQFYLTGA-TQIAYLGSLPVIGEKEV
IQADDEPTFSFFSGPYMVMTNLVWNGNRVTVKELNLP-THPHCSKLRL ADLLIAEQEHSS
KLRHPYLLQLMAVCLSQDLKKTRLVYERITIGTLFSVLHERRSQFPVLHMEVIVHLLLQI
SDALRYLHFRGFIHRSLSSYAIHIISPGEARLTNLEYMMES-QDGGV--QRDLTQVPLPT
QLYNWAAPEVILQKAATVKSDIYSFSMIVQEILT--DDIPWSGLNGSVIKEAIVLGNYLE
ADVRLPKPYYD-IVKSGIHVKQKDRTMNLQDIQYILKNDL----KDFTGAQRTQPTESPR
VQRYRLHPDVNVYLGLTSEHPRETPEMEIKEL----------KEM-GSQPHSPRVHSL-F
TEG--ALDPQAPDACLRARETQNQDA--------------PCPA-PFMAGEASSP---ST
DQASLCSFEINEI-SG-CLTLEDDI-EEPPGAASSFEADRSN-QVDE-LKSMEEL-----
-MDKME-REACCFWSEDK-----SSSEAGTEHSFEDWDWQNGSLSSLSLPEPVREAMSNL
NERSKTEEYYLSKCVLDLTIMQKIMQENVDRLRNIEQILDEVEMKQKEQEE--QMSLWTA
-------S------RKFANVYN---LPPAVGPPSLSYIPPVLQPLGGQQL-DASGNCPTL
ARFP---RT----------------------------------------------LPTLC
NPGKQNTDQQFQPTQGAKDSLERS-SIQNTSSQGRP-RESTAQAKATR-LNSA--LFTLS
GHQQGPSVSPSSHRDSTR---MSMEPVSSEIYNAESR--------N-KDDGEVHLKWKME
VKEMAEKAATGQLTVSPWHPQSSLTLESKA----ENEPDALLQPP--------------I
RSPENMDWQ---------RVIEYHRENDEPRGNG--RFDKMDNS----DQHG-RQPGPQS
FTSISHPSPG------------QNEQPEHSEA------VQASSDALVAIEKS----YSNE
STQSTCSPQSSE---DITDEFLTPDHEYFYSSAAQENLALETSS--PI-EEDFEGIQGAF
AQ------LQVSG-EEKFQMIKIL-GKNAEILPRSRFQPIQSTEDE----QEETLKES--
-PKELKEKDISLTDIQDLSSISCEPDSSFKEASCKTPKRNHAPTSVSTPLSP---GSVSS
AASRYKDCLERMTLQ-LKTGSASCWNSQESIQTLSDEFTSVR-ERAKRLDSLLTSSETPP
SRLTGL--KRLSSFTGSGSSRLAKACDAS-------------LPHATQRRSLPK--VEAI
SQHHIDELPPPSQELLDEIELLKQQQSSSTVSHE-----NTASDAGV-T--ANDQRHLEE
----QETDSKKEDSGMPWSKEAEDLGEDTERAHSTLDEDLERWLQPPEE-SMELQDLPK-
GSER-ETNTKDQEVGEEKRKREDSITPERRKSESVL-GTS-------EE-DELKPCFWKR
LGWSE------P----------------SRIIVLDQSDLSD-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---

--MSRAVHFPIPCPVQLGTLTDDSLEAQLHEYAKQGNYVKVKKILKKGICVDAVNSLGQS
ALFVAALLGHMKLVDVLVDYGSDPNHRCFDGSTPVHAAAFSGNQWILSKLLNAGGDL RLH
DEKGRNPQAWALAAGKDRSTQV--VEFMQ-RCTSHMKAII-QGFS-SDLLKKIDSPQRLI
CSPPWFGSLIQGSP---NSSPNRQ--LKPGIISAQNIYSFGFGK----------------
------------------------------------FYLTPG-MQLTYPGSLPVIGEKEV
IQADDEPTFSFFSGPYMVMTNLVWNRSRVTVKELNLP-TRPHCSRLRL ADLLIAEQEHSS
NLRHPNLLQLMAVCLSRDLEKIRLVYERITVGTLFSVLHERRSQFPVLHMEVIVHLLLQI
ADALIYLHSRGFVHRSLSSYAVHIVSAGEARLTNLEYMMES-RDDGV--HRDMTRVPLPT
ELYNWAAPEVILQKAATVKSDIYSFSMIIQEILT--DNIPWNGLDGSVIKETIALGSYLE
ADVRLPEPYYD-IVKSGIHAKQKNRTMNLQDIRYILKNDLK----ELLGAQKTQPTESPR
MQSYETHPDVNPCLGLTSEYQKDTPDLDIKEL----------KEM-GSQPISPTDPSVPT
GK--TTLTPQVLDSSLSVQEPENPNV-------------PSLPA-SCLAEEVRSP---MA
SQASLCSFEINEIYSG-CLDLGTDKEEECPGTALFLEGDKPN-QVDE-LPSLEEE-----
-LDKME-RELHCFCEEDK-----SFSEVDTDLSFEDGDWQNDSLSSLSLSEPTREDKGKM
SSWSKTD-EFVSKCVLNLKISQVMMQQNAEWLRKLEQEIDELELAQKELDN-QCRSLWDA
-------S------LRFANAK----FLLAVGPPYLTYLSPVTQSSEPRQS-ENGSYRLAL
ARCPGTERDFQE----GHFGKK-PEKLSDCGWKPF---TQTSEESSGDQSETNDQLPTVC
GPGKQNTGEQLPSTQEAKESLEEN-RNQNSR-----------------------------
----------------------SMESVSSEICNTKSR--------NNEDDGEAHLKWKMA
VKEMAEKAVSGQLLVPPWSPQSHLPFEDKV----ENEATHLPRPP--------------V
RGPESTYWQ---------HIVDYQRKNDELRGD--TKLGKMDSSDCDKNKPS-RQTGLQS
FTSFRYPFFR------------KHEQPQHNEV------SQASCDTSVGTEKF----YST-
------------------------------------------SS--PI-EEDFERIQSSL
AE------PQDYV-EEKFQIREIF-GKNAENLTKPQFQAMQCAEDE----QEETLEET--
-RKEPE-EKISLTDIQDLSSISYEQDGCFKETSCKTPKLKHAPTSVSTPLSP---ESLSS
ATSHYEDCLENTTFQ-VKRGSTFCWNGQESMRTFSAKFTTVR-ERAKSLESLLASSRPLP
AKLTDP--KKWSTYSGVGSSNNSAASV-T-------------SAHTTQRKSLPRELVEAT
SRHHIDELPPPAQELLDEIEHLKQQQVLSVVSH-EN----TAHDQSA-T--EHDKKHLEE
----QETNSSKD-SSFLSTKEIQDLE-DTERAHSSLDEDLERLLQSPEE-NVALLDPSK-
GSTR-EKKPEDEDIVEQKRKREESNKLERRNSDSFS-GAL-------EE-DELKPCFWKR
LGWSE------P----------------SRIIVLDQSDLSE-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---

--MAHPIPPPFPCPVQLGRIKGDSLEAQLHEYVREGNYVKVKKLLKKGIFVDAVNSMGQT
CLFTAALLGLGKIVDVLLEYGSDANHRCYDGSTPVHAAAFSGNQWILSKLLDEGGDLRVH
DKEGKTPQVWALSASKESSAQM--LEFIQ-QCSLHMQAAI-WNLP-SDLLRKVGSSKALI
CSPSRFGGLVQGNA---EIPLGKL--LKGQPSVAKNIYSFGFGK----------------
------------------------------ADALFQFYLTGS-GHLGYLASLPIIGEKDV
VQADDEKAFSYPVGPYMTMSNLVWGGSRVTVKELSLQ-TQQGRGNLRLADLLLAEQQHSS
KLRHPHLLQLMAVCLSCDLEKTRLVYERVHFGSLYSILHERRAEFPVLQTETILHVLLQV
VDALRFLHSRGFVHRSLSSYAIQIVSSGEAKLCNLEYMIES-KDSGE--HSDLTRIPVPV
QLFRWCSPEIILEKPGTVKSDLYSFCAVLQETLT--ESPPWKDVEDSAIKQLILSGEQLA
ADARLPLIYYD-VVKSGLEPKQKNRSMKLQDIQYILKKDL----KDLVKSEG----GILK
AQRSAVLADVNICWASAFSFKKRTVEIQEKEI----------SKA-GEFLGA--GC----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---

--MAHALPLPIPCPVQLGSLKGDSLEAQLHECVRQGNCGKVKKLLKKGTFVDAVNSMGQT
SLFTAALLGLGKIVDVLLDYGSDPNHRCYDGSTPVHAAAFSGNQWVLSKLLDEGGDL RVH
DEGGKNPQYWAMSAGKESSAQM--LEFIQ-RCTFHMQAA-IQNFP-CDPVRKICSSKALV
SSPSRFGGLVQGNA---DSPLGRF--LKDGVNAAKNIYSFGFGK----------------
------------------------------------FYLAGS-RHVGYLASLPIIGEKEV
VQADDEPTFSYHVGPCMIMTNLMWGSSRVTVKELSFQ-PHQNCAKLRL ADLLIAEQEHSS
KLRHPHLLQLMSVCLSSDLEKTRLVYERVNFGSLYSILHERRAEFPVLRMETILHILLQI
NDALRFLHSRGFIHRTITSYAIQIVSSGEAKLCNMEYMIES-KDGGE--HSDLTRIPVPA
QLYKWCSPEVILEKSVTVKSDIYSFCTVMQEALT--ETLPWKGIEDSVIKQLIISGQQLE
ADVRLPVPYYD-IVKSGLESKQKNRSMTLQDIQYILKNDL----KDLTKSQSCHADEMAK
AQRPAVFADINICLSSTFSYRKRTLELNEKGI----------TEA-DSSAAP--RYPIFP
EENNALVDLEAPTSLQLAAQENNHDA--------------A-----SETQMTCSV---SD
VDDSLCSFEMNEVFAS-CPDFHEDFLEEGAELSQTLKDKKRQ-QKEK-DENVLGDLFLSP
GMCCEE-KPV--Y-E-EG-----SISESVAEYTTEEEEGKSEASDLNVLAQVRGDAGRR-
STLSSNE-HHISKCVLNLKIVQSMLQQAAESLCRTEEKLDKLEAVEKQRK--LLQEVWTN
-------Q------LSNPFSGAHAFLWKAVGPPSSDYIPPLVTCQSQGAL-RGDGF-QTV
SNVSEEMW-----------------AIQNEKWKCF---HQRSK---GKKENSQHD-LS--
----------FNEVSGKG---DVV-M------SG-----IQAEGRAKG-WNCH--CFRSD
SHSSA-SGS-----KEER---WCYPKPASEIHSMKI----------SEERRMMQPEWRTE
VRQMARKVASGQLELIAPY----LASDCTS----ESEVESI----KEA-FQHVTSRVQKG
RDQREDRWRTGDNAEPWDGGCEDGSESEESDLES--IFRSSGGGSCQS--PS--------
----------------------QDEQAESGLS------VHKNSVTFQQIETV----SRGH
SRELPCSFSSYP---SESEEFLTPDPDYFLPAAVEETAALFLRSVGVI--AAFPVCQYLY
SL------LSTGG--------------N--------ELPVSKVEGSTEAAQEVISREL--
-QEDSEEKDISVTDIQDLSSIPCKEENYYEDINCRSPGVSHAPPSVSTPISS---EERIP
VAFEKHRCCHEVVLD-SS---SCIC--QEVSSAVSRTFTTAY-EEER-STEV--------
----------LSSSPSVCSSGLNEPVEKTCFVGGGSWHS-----------GLLVCQQPVA
PVHLLDELPAPAQELLDEIECLKQQDSIARDSVE-----EGLCDCRV-QKNDSDRIKMEG
----TEAKKEIEISENVWTMETFNLAEETERAHSTLDDALERILYAVPA-DEQIQEQQQE
DEEI-Q-----------------GC---------AL-GLADNCYFIHSF-ILFMFCVQTC
DGLVS------K----------------WAVAL---------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---

----------------------------------------------SHIAVHFPLALGQS
ALFVAALLGHMKLVDVLVDYGSDPNHRCFDGSTPVHAAAFSG NQWVLSKLLNAGGDLRLH
DEKGRNPQAWALAAGKDRSTQM--VEFMQ-RCTSHMKAII-QGFS-YDLLKKIDSPQRLI
CSPPWFGSLIQGSP---NNSPNRQ--LKPGIISAQNIYSFGFGK----------------
------------------------------------FYLTPG-MQLTYPGSLPVIGEKEV
IQADDEPTFSFFSGPYMVMTNLVWNRSRVTVKELNLP-TRPHCSRLRL ADLLIAEQEHSS
NLRHPNLLQLMAVCLSRDLKKIRLVYERITVGTLFSVLHERRSQFPVLHMEVIVHLLLQI
ADALIYLHSRGFVHRSLSSYAVHIVSAGEARLTNLEYMMES-QDNGV--HRDMTRVPLPT
QLYNWAAPEVILQKAATVKSDIYSFSMIIQEILT--DNIPWNGLDGSVIKETIALGSYLE
ADVRLPEPYYD-IVKSGIHAKQKNRTMNLQDIRYILKNDLK----EFLGAQKSQPAESPR
MQSYEAHPDVNPCLGLTSEYQKDALDLDIKEL----------KEM-GSQLHSPTDHSIPT
GK--TTLTPQVLDPNLSAQEPENPNV--------------PSPPALCLTEEVRSP---TA
SQASLCSFEINEIYSG-CLDLGTDKGEEWPETALSPEVDKPS-QVDE-LPSLEEE-----
-LDKME-RELHCFCE-DK-----SFSEVDTDLSFEDGDWQSDSISSLSLSEPTREDKGKI
SSWSKTD-EYVSKCVLNLKISQVMMQQNAEWLKKLEQELDELELAQKELDN-QCRSLWDA
-------S------LRFANAE----FLLAVGPPSLTYLPPVIQLSEPRQS-ENGDYWLAL
ARSPGTERDFQE----EHFGKN-PEKPGDCGWKPF---IQVSEESSRDQSETNNQLPTVC
GPGKQNTDEQLPSIQEAKESLERN-RSQNT------------------------------
-------------------K--SVGSVSSEIYNIKSR--------NNEDDGETHLKWKMA
VKEMAEKAVSGQLLVP-WNPQSSLPFASKV----ENEATALPQPP--------------V
RGPESTYWQ---------HIVEYQRENDEMKGN--MKFGKMDNSDCNKNKHS-RQTGLRS
FTSIRYPFFR------------KYEQPEHSEA------SHASCDTSVGTEKF----YST-
------------------------------------------SS--PI-EEDFERIHISL
AE------PQGYV-EEEFQIREIF-GKNAEILTEPQFQAIQSAEDE----QKEAPEET--
-LKEPKQKDISLTDIQDLSSISYEKDGYFKESSCKTPKLKHAPTSVSTPLSP---ESISS
AASHYEDCVENATFQ-VKKGSSFCWNSQESMRTLSAKFTTVR-ERAKSLESLLASSRPLP
AKLTDP--KKWSTYSGVSS-IISTASV-T-------------SANATQRKSLPRELVEAT
SQHLIDELPPPAQELLDEIEHLKQQHVLSMVSNE-N----TAHDLSA-T--ENDKKHLEE
----QETNSSKD-SSFLSTKEIQDLE-DTERAHSSLDEDLERLLQSPEE-NMALLDPSK-
GSTRLERKPKDQDAVEQKIKRNESIKPERRKSDSFL-GTL-------EE-DELKPCFWKR
LGWSE------P----------------SRIIVLDQSDLSE-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---

--MSRAVRLPVPCPVQLGTLRNDSLEAQLHEYVKQGNYVKVKKILKKGIYVDAVNSLGQT
ALFVAALLGLRKFVDVLVDYGSDPNHRCFDGSTPVHAAAFSGNQWILSKLLDAGGDL RLH
DERGQNPKTWALTAGKERSTQ--IVEFMQ-RCASHMQAII-QGFS-YDLLKKIDSPQRLV
YSPSWCGGLVQGNP---NGSPNRL--LKAGVISAQNIYSFGFGK----------------
------------------------------AMPWFQFYLTGA-TQMAYLGSLPVIGEKEV
IQADDEPTFSFFSGPYMVMTNLVWNGSRVTVKELNLP-THPHCSRLRL ADLLIAEQEHSS
KLRHPYLLQLMAVCLSQDLEKTRLVYERITIGTLFSVLHERRSQFPVLHMEVIVHLLLQI
SDALRYLHFQGFIHRSLSSYAVHIISPGEARLTNLEYMLES-EDRGV--QRDLTRVPLPT
QLYNWAAPEVILQKAATVKSDIYSFSMIMQEILT--DDIPWKGLDGSVVKKAVVSGNYLE
ADVRLPKPYYD-IVKSGIHVKQKDRTMNLQDIRYILKNDL----KDFTGAQRTQPTESPR
VQRYGLHPDVNVYLGLTSEHPRETPDMEIIEL----------KEM-GSQPHSPRVHSL-F
TEG--TLDPQAPDPCLMARETQNQDA--------------PCPA-PFMAEEASSP---ST
GQPSLCSFEINEIYSG-CLILEDDI-EEPPGAASSLEADGPN-QVDE-LKSMEEE-----
-LDKME-REACCFGSEDE-----SSSKAETEYSFDDWDWQNGSLSSLSLPESTREAKSNL
NNMSTTEEYLISKCVLDLKIMQTIMHENDDRLRNIEQILDEVEMKQKEQEE--RMSLWAT
-------S------REFTNAYK---LPLAVGPPSLNYIPPVLQLSGGQKP-DTSGNYPTL
PRFPRM-------------------------------------------------LPTLC
DPGKQNTDEQFQCTQGAKDSLETS-RIQNTSSQGRP-RESTAQAKATQ-FNSA--LFTLS
SHRQGPSASPSCHWDSTR---MSVEPVSSEIYNAESR--------N-KDDGKVHLKWKME
VKEMAKKAATGQLTVPPWHPQSSLTLESEA----ENEPDALLQPP--------------I
RSPENTDWQ---------RVIEYHRENDEPRGNG--KFDKTGNNDCDSDQHG-RQPRLGS
FTSIRHPSPR------------QKEQPEHSEA------FQASSDTLVAVEKS----YSHQ
SMQSTCSPESSE---DITDEFLTPDGEYFYSSTAQENLALETSS--PI-EEDFEGIQGAF
AQ------PQVSG-EEKFQMRKIL-GKNAEILPRSQFQPVRSTEDE----QEETSKES--
-PKELKEKDISLTDIQDLSSISYEPDSSFKEASCKTPKINHAPTSVSTPLSP---GSVSS
AASQYKDCLESITFQ-VKTEFASCWNSQEFIQTLSDDFISVR-ERAKKLDSLLTSSETPP
SRLTGL--KRLSSFIGAGSPSLVKACDSS-------------PPHATQRRSLPK--VEAF
SQHHIDELPPPSQELLDDIELLKQQQGSSTVLHE-----NTASDGGG-T--ANDQRHLEE
----QETDSKKEDSSMLLSKETEDLGEDTERAHSTLDEDLERWLQPPEE-SVELQDLPK-
GSER-ETNIKDQKVGEEKRKREDSITPERRKSEGVL-GTS-------EE-DELKSCFWKR
LGWSE------S----------------SRIIVLDQSDLSD-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---

--MSRPVHLPVPCPVQLGSLRNDSLEAHLHEYVKEGNYVKVKKILKKGIYVDAVN S LGQT
ALFIAALLGLTKLVDVLVDYGSDPNHRCFDGSTPVHAAAFSGNQWILSKLLDAGGDLRLH
DEKGRSPRAWALGAGKERGPAM--LDFIR-RCAVHMQAVL-QGFS-SDLLGKIDSPQRLV
CSPPRFGSLMQGNS---SGSPNRP--LKAGVVSTRNIYSFGFGK----------------
------------------------------TVLWFQFYFTRG-KPLAFLGSLPVIGEKEV
IQADDEATFSFFSGPYMVMTXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXX
KLRHPHLLQLMAVCLSQDLKTTRLVYERVTIGTLFSVLHERRSQFPILHMEAIVHLLLQL
SDALRYLHSHGFVHCSLSSYAVHIVSTRQARLTNLEYMTEX-XXXXX--XXXXXXXXXXX
XXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXDIPWNGLDGSLIKEAVVLGNYLE
TDVRLPKPYYD-IVQTGIQVKQRDRTMNLQDIQYILRNDLK----DLIGAQRTQPTESPR
VQRYEPHL--DVYLGLMSEHPKEPPNLEIREL----------KET-GSQLRSPRGYSSPA
EK--TALEAQAPGPSQAAGVAENPGA--------------AASASSVV-EEARSP---GT
SQASLCSFEINEIYSG-CLNVGDDKEEESPGSVSATEEGGPT-QVDE-LQSLEEE-----
-LDKME-REACSLCSEDD-----SSLEAETELTLEDWDWENSSRGSVHTHEPTREARGGV
SIRSVTD-DYVSKCVLNLKIAQTVMHQNDDMVRNIYQIINEAERIQREQE--EHMSLWVS
-------A------RLFADISD---VPLAVGPPTLNYIPPVMPLPGGQQQ-DTGGNSQTL
ARSPK-------------------------------------------------TLPARG
GSGKQNRGEPLQPTQGAKDSLDRS-RNPDTDSHRRP-KESSVQARVTQ-LNSA--VFPVS
SRPQGPLQAPSPPQNSTR-----ICMVSCEICNPKSR--------NC-DDEGVHLKWKKE
VKEMAERAAAGQLTVPGWHPQSSVVLESEA----ESEPRPLLQPR--------------T
GNPENMDWQ---------QAVEHPSKNDKLEGN--SKCDTTNKSDQPSGQPG-LQSFPXX
XXXXXXXXXX----------------XXXXXX------XXXXXXXXXXXXXX----XXDH
SRQSTCSPESSE---DATDEFLTPDYEYFNSLTAQEHLALETSS--PI-EEALGGTQGTL
AP------PADSD-EEKFQMRKNP-GKDAKTLSESQQPVLXXXX-X----XXXXXXXX--
-XXXXXXXXXSLVDIQDLSSISCERDGSVQEASCKTPKGNHAPTGVSTPRSP---GSVSS
SASQYKDCFGSLTWK-AKTGSASCWNSQESLQTTSDKSTTVR-EKVRSLDSLLTSSETSP
SRMTDF--KRWSAFTGPGSPSRAKVSG-T-------------SLPTTQRRSLH--KAEVL
SQHHVDELPPPPQELLDEIEHLKQREALPAVIGEED----TARDRGH-S--THDQRYLEE
----QETNSKKEDGRVLWAQESQDLE-DSERAHSTLDEDLE-WLQPPEE-SRGLPELLE-
DSAR-ETDTQHQEVGEKKIKGEDSTKLERRKSESLL-GTS-------DE-DELKPCFWKR
LGWSE------P----------------SRIIVLDPTDLSDS------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---

--MSRAVPLPLPCPVQLGTLRNDSLEAQLHEYVKQGNYLKVKKILKKGIYVDAVNNLGQT
ALFVAALLGLRKLVDVLVDYGSDPNHRCFDGSTPVHAAAFSGNQWILSKLLDAGGDL RLH
DERGQNPKTWALTAGKERSTQ--IVEFMQ-RCALHMQAII-QGFS-YDLLKKIDSPQRLV
YSPPWFGSLVQGNP---NGSPNRL--LKAGVISAQNIYSFGFGK----------------
------------------------------AMPWFQFYLTGA-TQIAYLGSLLVIGEKEV
IQADDEPTFSFFSGPYMVMTNLVWNGS RVTVKELNLP-THPHCSKRRLADLLIAEQEHSS
KLRHPYLLQLMAVCLSQDLEKTRLVYERITIGTLFSVLHERRSQFPVLHMEVIVHLLLQI
SDALRYLHSQGFIHRSLSSYAVHIVSPGEARLTNLEYMLES-KDRGE--QRDLTRVPLPT
QLYNWAAPEVILQKAATVKSDIYSFSMIIQEILT--DDIPWNGLDGSVIKEAIVLGNYLE
ADVRLPKPYYD-IVKLGIHIKQKDRTMNLQDIRYILKNDL----KDFTGTQRTQPTESPR
VQRYGLHPDVNVYLGLTSEHTRETPDMEIIEL----------KEM-GSQPHSPRVHSL-F
TEG--TLDPQAPDPCLMARETQNQDI--------------PCPT-PFMAEEASSP---ST
GQASLCSFEINEIYSG-CLTLEDDI-EEPPGAASSLEADGPN-QVDE-LQSMEEE-----
-LDKME-REACCFCSEDE-----SSSKAETEYSFEDWDWQNGSLSSLSLPESTRETKSNL
NNRSMAEEYLISKCVLDLKIMQTIMHENDDRLRNIEQILDEVEMKQKEQEE--RMSLWAT
-------P------REFTDVYN---LPPAVGPPSLNYIPPVLQLSGGQQP-DTSGKWPTL
PRFPRM-------------------------------------------------LPTLC
DPGKQNTDEQFQGTQGVKDSLGRS-RIQNTSSRGKP-RESTAQAKATQ-FDSA--LFTLS
SHWQGPSASPNSHWDSTR---MSVDPVSSEIYNAESR--------N-KDDGEVHLKWKME
VKEMAEKAATGQLTVPPWHPQSSLTLESEA----ENEPDALLQPP--------------I
GSPENTDWQ---------RVIEYHRENDEPRGNA--KFDNTGNNDCDSDQHD-RQPRPGS
FTSIRHPSPR------------QKEQPEYSEA------FQASSDALVTVEKS----YSHQ
SMQSTCSPESSE---DITDEFLTPDDEYFYSSTAQENLALETSS--PI-EEDFEGIQGAF
AQ------PQVSG-EEKFQMRKIL-GKNAEILPRSQFQPIRSTEDE----QEETSKES--
-LKELKEKDISLTDIQDLSSISYEPDSSFKEASCKTPKINHAPTSVSTPLSP---GSVSL
AASQYKDCIESITFQ-VKTESASCWNSQEFIQTLSDEFISVR-ERAKKLDSLLTASETCP
SRLPGL--KRLSSFIGAGSSSLVKACDSS-------------PPHATQRRSLPK--VEAF
SQHHIDELPPPSQELLDEIELLKQQQGSSTVLHE-----NTASDAGG-T--ANDQRHLEE
----QETDSKKEDSSMLLPKETGDLGEDTERAHSTLDEDLERWLQPPEE-SMELQDLPK-
GSER-EINIKDQEVGEDKRKREDSITPERRKSESVL-GTS-------EE-DELKPCFWKR
LGWSE------S----------------SRIIVLDQSDLSD-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---

--MSRAVHLPVPCPVQLGSLRNDSLEAQLHEYVKQGNYVKVKKILKKGIYVDAVNSLGQT
ALFVAALLGLTKVVDVLVDYGSDPNHRCFDGSTPVHAAAFSGNPWILSKLLDAGGDL RLH
DEKGQNPQTWALTAGKERSTVM--VEFMQ-RCASHMQAII-QGFS-YDLLKKIDSPQRLI
SGPPRLGGLIQGNP---NGSPNRL--LKAGVISAQNIYSFGFGK----------------
------------------------------------FYLTGG-AQLAYLGSLPVIGEKEV
IQADDEPTFSFFSGPYMIMTNLVWNGSRVTVKELNLP-THPHCSRVRL ADLLIAEQEHSS
KLRHPHLLQLMAVCLSQDLEKTRLVYERITVGTLFGVLHERRSQFPVLHMEVIVHLLLQI
SDALRYLHSRGFIHRSLSSYAIHIVSAGEARLTNLEYMMES-QDGRV--HRDLTRVPLPT
QLYNWAAPEVILEKAATVKSDIYSFSMIIQEILT--DNIPWNGLDGSVIKEAIVLGNYLE
ADVRLPKPYYD-IVKSGIQVKQKDRTMNLQDIRYILKNDLK----DFLGAQRTQPTESPK
MQRYELHPDVNVCLGLMSEHLKETPNLEIKEL----------KETAGSRLHSPTE-----
--K-ATPDPQVLDPGLMAKETQNRDA--------------ASPACSVMEEDARGP---SP
GQASLCSFEINEIYSG-CLDRGDNTKEEPPGADSSVVGAGPS-QADE-LKSMEEE-----
-LEKME-REACCFYDEDE-----SSSEADTELSFEDWDWQNGSLSSPSLPELAREAKGNG
SNRCMTE-EYISKCVLNLKISQTLMYQNADLLRSTEQRIDKLEMIQKGQE--EYRSLWAS
-------S------REFTNIYD---SPSALGPPASTYVPPVMQLPRGQQL-DTSGNCQTL
TRSS-MVRDFQG----GHFGKR-SRKRSDCGWKPV---IQVSEESTGDQSEKSHQLPNFS
GPGKQGTSEQSQPSQGAKHSLERN-RSPNTS-----------------------------
--------------------RISVESVSSEICHTKLR--------NNEDDGEVHLKWKLE
VKEMAERAATGQLAVPPWHPQSSATLEDEA----KDEPDSLLQPP--------------L
GDPEKVGWQ---------CTVEYPRENDESREN--GKCNKMGNSDCDSDQYG-KQPGPQS
FNSIRHLSPS------------KNVYPEHSEV------FQASSDASVVIEKS----YSDQ
SMQSTCSPESSE---DVTDEFLTPDYEYFHSSTAQENLALETSS--PI-EEDFEGIRDAF
AQ------PRGSG-EEKFQMRKSL-GRNAEILTRSQFQPIRTTEGE----QEETLKES--
-PKELKEKDISLTDIQDLSSISYEQDGSFKEVSCKTPKINHAPTSVSTPLSP---GSSSS
AASRYKDCLESITFQ-IKTGSTSCWNSQESIQTSSDRFTTVR-EKAKSLDSFLTSSETAP
SRLTDL--KRLPAFTGAGSSSIAKSPD-T-------------SSHATQRRSLQKALVEAI
SQHHVDELPPPSQELLDEIEHLKRQQASSTVLR-EN----TASYLGV-T--VNDQSHLEE
----QETNSKKEDSSMLWTKETQDLEEDTERAHSTLDEDLERWLQPPED-STELQDLPG-
GSTR-EANTKDQEVGEKKRKGEESFKSERRKSDSFL-GNS-------EE-EELKPCFWKR
LGWSE------P----------------SRIIVLDQSDLSD-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
KLRHPYLLQLMAVCLSQDLEKTRLVYERITIGTLFSVLHERRSQFPVLHMEVIVHLLLQI
SDALRYLHFQGFIHRSLSSYAVHIVSPGEARLTNLEYMLES-KDRGE--QRDLTRVPLPT
QLYNWAAPEVILQKAATVKSDIYSFSMIMQEILT--DDIPWNGLDGSVIKEAIVLGNYLE
ADVRLPKPYYD-IVKSGIHVNQKDRTMNLQDIRYILKNDL----KDFTGTQRTQPTESPR
VQRYGLHPDVNVYLGLTSEHTRETPDMEIIEL----------KEM-GSQPHSPRVHSL-F
TEG--TLDPQAPDPCLMARETQNQDA--------------PCLA-PFMAEEASSP---ST
GQASLCSFEINEIYSG-CLTLEDYV-EEPPGAASSLEADGPN-QVDE-LQSMEDE-----
-LDKME-REACCFCSEDE-----SSSKAETEYSFEDWDWQNGSLSSLSVPKSTREAKSNL
NNRSMTEEYLISKCVLDLKIIQTIMHENDDRLRNIKQLLDEVEMKQKEQEE--RMSLWAT
-------S------REFTDVYN---LPPAVGPPSINYIPPVLQLSGGQQP-DTSGKCPTL
PRFPRM-------------------------------------------------LPTLC
DPGKQNADEQFQGTQGVKDSLERS-RIQNTSSRGKP-RESTAQAKATQ-FNSA--LFTLS
SHLQGPSASPNSHWDFTR---MSVDPVSSEIYNAESR--------N-KDDGEVHLKWKME
VKEMAEKAATGQLTVPPWHPQSSLTLESEA----ENEPDALLQPP--------------I
GSPENTDWQ---------RVIEYHRENDAPRGNA--KFDNTDNNDCDSDQHD-KQSRPGS
FTSIRHPSPR------------QKEQPEYSEA------FQASSDALVAVEKS----YSHQ
SMQSTCSPESSE---DITNEFLTPDDEYFYSSTAQENLALETSS--PI-EEDFEGIQGAF
AQ------PQVSG-EEKFQMRKIL-GKNAEILPRSQFQPIRSTEDE----QEETSKES--
-LKELKEKDISLTDIQDLSSISYEPDSSFKEASCKTPKINHAPTSVSTPLSP---GSVSS
AASQYKDCIENITFQ-VKTESASCWNSQEFIQTLSDEFISVR-ERVKKLDSLLTASETCP
SRLPGL--KRLSSFIGTGSSSLVKACDSS-------------PPDATQRRSLPK--VEAF
SQHHIDELPPPSQELLDEIELLKQQQGSSAVLHE-----NTASDAGG-T--ANDQRHLEE
----QETDSKKEDSSMLLSNETGDLGEDTERAHSTLDEDLERWLQPPEE-TMELQDLPK-
GSER-ETNIKDQEVGEDKRKREDSITPERRKSESVL-GTS-------EE-DELKPCFWKR
LGWSE------S----------------SRIIVLDQSDLSD-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---

------------------------------------------------IYVDAVNSLGQT
ALFVAALLGLTKFVDILVDYGSDPNHRCFDGSTPVHAAAFSGSQWILSKLLDAGGDL RLH
DEKGQNPQTWALAAGKDRSTPM--VEFMQ-RCTSHMQAIM-QGFS-YDLLKKIDSPQRLI
CNPPSLAGFLQGSP---NGSPNQP--LKAGVISTQNIYSFGFGK----------------
------------------------------------FYLTGG-TQLAYLGSLPIIGEKEV
IQADDEPTFSFISGPHMVMTNLVWNG SRVTVKSLNLP-TH--SSRLRLADLLIAEQEHSS
KLRHPHLLQLMAVCLSQDLEKTRLVYERITIGTLFSVLHERRSEFPVLHMEVMVHLLLQI
ADALRYLHSRGFVHRSLSSYAVHIVCAGEARLTNLEYML---------------------
------------------------------------ESVPWNDLDGSVIKEAILLGNYLD
ADVRLPKPYYD-VVKSGIQVKQKDRTMNLQDIQYILKNDLK----ENIGAQRTQPVESPR
VQRCEPYPDVSVYLGLTSEHPKASADLEIKEL----------KES-GSQPHSPRGHSSPT
AK--AALAPQAPDPHLKAQVSQNPDA--------------PPPSAPFV-AETKSP---SA
GQDGLHSFEINEIYSG-CLNVGDDPEEECPGGTSAREGGKPN-QADE-LPSLEEE-----
-LDKME-EE-AHLCDEDE-----SSSEADTEIFFGDWDWQNSSLSLLSLPEPTKEAKGKV
SSWSKTE-EYISKCVLNLKISQTMAHEITDLVGNIEQKLDKVELIQKK-----HISLWTA
-------S------RLFPDVCD---LPRAVGPPTLNYIHPVMQVSGGPQP-DTNGSCPTL
PRSPRTMKEFQG----GHFGKK-LKRQSSSGWKPF---TQVSEENTKDQPEGRHQLSTLC
DPGKQDTGEPFQATQGAKDCLEKK-KNQDS------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---

--MSRAVHLPLPCPVQLGSLRNDSLEAQLHEYVKQGNYVKVKKILKKGVHVAAVN S LGQT
PLFIAALLGLTKVVDILVDYGSDPNHRCFVGSTPVXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX--MVEFMQ-RCALHMQTII-QGFS-YDLLKKIDSPQRLI
CSLPRFGGLMRGNP---NGSPNRL--LKAGVISAQNIYSFGFGK----------------
------------------------------AVLCFQFYLTGG-TQLAYLGSLPIIGEKEV
IQADDEPTFSFFSGPYMVMTNLMWNGSRVTVKELSFP-THPHCSRLRLADLLIAEQEHSS
KLRHPHLLQLMAVCLSQDLEKTRLVYERITVGSLFSVLHERXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXX-------XXX--X---XXXXXXXX------XX-----XX------
XXXXXX---XXX--XX-X---XXXXXXXX--XX-----X---XX------XXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXTMNLQDIQYILKNDL----KDFIGAQRTQPAESPR
VQRYELHPDVNVYLGLTSEHPKETLDLQVKEL----------KET-GSQPPSPRGPSSPT
EKA--TPEPPVPDPSPEAQEPQNQDA--------------ASPA-CSVAEEARSS---SP
GLASLCSFEINEIYSG-CLDLGAGL--------------SSN-QVDE-LKSMEEE-----
-LEKME-REACCFRDEDE-----SSSEAGTELSFEDWDWQNSSLSLLCLP-PARGARGTV
SRRATT-EEYFSKCVLILKISQTIMHQIDYLLCSI--LLDETETMQKELEE--RWSLWAS
-------S------REVPRARD---FPAAVSPPSLNYVPPVMQLPGGRQP-DTGGGSPAP
ARSPRT-------------------------------------------------LPALR
DPGKQSTGEQFQPTHGAKDSSERK-RNQHASSQGRL-RESSARTKMTQ-LSSA--LLTMP
SHPQGSPSSSSPGWGSTR---ISMESVSSEIFNAKSR--------NSEDDGETHLKWKRE
VKEMAEKAASGQLAVLSWRPQNSLTLENEA----ENEPAPLLQPP--------------S
RVSEHVDWQ---------QAVQHPKKSDAPGGNE-KCDXXX---------XX-XXXXXXX
XX--------------------------XXXX------XXXXXXXXXXXXXX----XXDQ
FRQSTCSPESSE---DVTDEFLTPDYEYFYCATAQENLALEXXX--XX-XXXXXXXXXXX
XX------XXXXX-EEKFQMRKRF-GKNAEILTKCQLQPIRSTEGE----QEETLKES--
-PKEMKEKDISLTDIQDLSSISYEQDGSFKEVSCKTPKINHAPTSVSTPLSP---GSVS-
AASQYKDCLESITVQ-VKTGSTSCWNRQEFIQTLSDKFVTVR-ERAKRLDSLLTSSATPP
SRLTNL--RRLPAFPGAGSSSIAKAPDTS-------------SP-ATQKRSLPK--VEAI
SQHNIDELPPPSQELLDEVEQLKWQEASSTVVDE-----NTASHLDI-T--ACDQSYLEE
----QETNSKKEDSSMLWTKETEDLEEDTERAHSTLDEDLERWLLPPED-VTELQDLPT-
GSAR-ETNTTDKEVGEEKRKGENSTTLXXXXXXXXXXXXX-------XX-ELKKPCFWKR
LGWSE------P----------------SRIIVLDQSDLSD-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---

------------------------------------------------ICVDAVNSQGQT
ALFVAALLGLTKLVDVLVDYGSDPNHRCFDGSTPVHAAAFSGSQWILS------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---

------------------------------------------------IYVDTVNSLGQT
ALFTAALLGLPKLVDVLVDYGSDPNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXX---XXXXXXX--XXXXXXXXXXXXXXFWLQ----------------
------------------------------------FYLTGG-TQLAYLGSLPVVGEKEV
IQADDEPTFSFCSGPYMVMTNLVWNGSRVTVKELNFA-THSNCSKLRFADLLIAEQEHSS
KLRHPHLLQLMAVCLSQDLEKTRLVYERINVGSLYSILHERRSQFPVLHMEMIVHLLLQI
NDALRYLHSRGFVHRSLSSYAIHIVSAGEARLTNLEYMIES-QNRDA--QKDLTRVPIPV
LLYSWSAPEVILQKAATVKSDIYSFCIIIQEILT--XXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXX-XXXXGIQVKQKDRTMN-QDIRYILKNDL----KDLIETQRTHPVENTN
VQKYKKHHDINIYFGMASETKRETLDLEVREL----------KET-GCQLDSPQGHSALP
EK--AALDCEVLNHSMTAKETESQAI--------------A-----SELTRACSP---SC
GDESLRSFEINEIYSC-YLDTCDNDVGEIITSDIFLGNGKNQ-GK-E-TESITGEC---P
EIKKAS-HSD--YSE-DD-----AISEGGTESSSEDWEPLNDAFDSHV-QEVTRETKPDM
SSESRTE-QSLGKCVLNLKISQTLMQQLTESLQNAEQKIGKLEMMRKRQEQ-QMSSSWAA
-------L------KTCARDCDPSAVWAAFGPPAKCYSPPSTQLPGQHAG-HVDHF-QNL
VKTARAXX-----------------XXXXXXXXXX---XXXXX---XXXXXXXXX-XX--
----------XXXXXXXXXXXXXX-X-----XXX---XXXXXXXXXXX-XXXX--XXXXX
XXXXX-XXX-----XXXX---MGVESRSSEFYNSKT----------RNDDREARLKWTXX
XXXXXXXXXXXXXXXXXXX----XXXXXXX----XXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXX--XX--------
----------------------XXXXXXXXXX------XXXXXXXXXXXXXX----XXEH
SVESPCSIDSSE---DVTDEFLTPDPDYFYTPTVQEHSEVKXXXXXXX--XXXXXXXXXX
XX------XXXXX-XXXXX----X-XXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXX--
-XXXXXXXXXSLTDIQELSSISWEQGSPCKEIPCKTPRTSHGPTSVSTPLSP---ASCWD
SQKS--------------------------IRTISNVFTRAR-KRAGELIPL--------
----------LSEMPSF---GWTDHXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-----XXXXXXXX-XXXXXXQRHLEE
----KLIPNKAEDGSILWTKETLYLTEETDRAHSTLDEDLERWLCDSSE-KKKLQEDLTE
SSAR-ETSVTAQEVGEKKKKGE-GAKTEKRKTDSFP-GSPEGIFLLIE----LKPGLWHC
LGWTQ------P----------------SRIIVLDQSNNSD-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---

-----------------------------------------------GIYVDAVNSLGQT
ALFIAALLGLTKLVDVLVDYGSDPNHRCFDGSTPVHAAAFSGNQWILSKLLDAGGDLRLH
DEKGRSPQAWALAAGKERSPEM--VEFMQ-RCAVHMQAII-RGFS-CDLLRKIDSPQRLI
SSPPRFGSLKQGNP---TGSPNRL--LKAGVVSAQNIHSFGFGK----------------
------------------------------------FYVTGG-KQLAYLGSLPVIGEKEV
IQADDEPAFSFSTGPYMVMTNLVWNGSRVTVKELNLP-THAHCSRLRLADLLIAEQEHSS
KLRHPHLLQLMAVCLSQDLETTRLVYERITIGTLFSVLHERRSQFPMLHMEVIVHLLLQI
SDALRYLHSRGFVHCSLSSYAVHIVSTGEARLTNLEFMMES-QDGGA--HKDLTRVPLPT
QLYNWAAPEVILQKAASLKSDIYSFSMIVQEILTVTDSIPWNGLNGSVIKEAVVLGNYLE
ADVRLPKPYYD-IVKSGIQVKQKDRTMNLQDIQYILKNDLK----DFIGSQRTQPTESPR
VQRYEPHPDVNIYLGFTSEHPKEPLNLEIKEL----------KET-GSQLHSPRGYSSPT
EK--AALGVQAPDPSLVARETQDQGA--------------AFPVSSVA-EEARSP---SE
GQASLCSFEINEIYSG-CLDVGDDKEEEPPRSVSSLEEDRPT-EVDE-LQSMEEE-----
-LAKME-REACSLCDEDG-----SSLEAETELSFEDWDWENGSLRSPSIGEPTREAKGNV
-NRSVTE-EYISKCVLNLKIAQTLMHQNADLLRNTQQKINKLEMIQREQE--EHRSFWAT
-------S------GEFANVYG---TPSALGPPALGYVPPVMPLSGDQQL-GTSGNSQTL
ARSPRIVQDFQE----GHFGKR-SRKRSNYGWKPFAPFTQVSEKSPGDQSEKSHQLPTLC
GSGKQNRGEKPQPTQGAKDSLDGS-RNPDTD-----------------------------
--------------------RMRMGSVSSEICHPKSR--------NR-EDEEVHLKWKTE
VKEMAERAAAGQLMVSPWHPQKSVALESEA----ENKPDPLLQPP--------------T
RNPENVDWQ---------QAIEYPRKNDKPGGN--GKCDKTDQSDQPSGQPG-SWSFTSK
LLGVRHLSLR------------KNDQPEHSEA------FQASSDAPVGTEKS----YST-
------------------------------------------SS--PI-EEASEGIQGAL
AQ------PPGSGEERPQMTGRIL-GRNDETLSKSQFQPIRSAESE----QEESLKES--
-PKEQKEKDISLMDIQDLSSISCERDSSFKEASCKTPKINHAPTSVSTPLSP---GSVSS
SASRYKDGLESITFQ-VKTGSTSCWNSQESLRTSSDKFTTVR-EKAKSLDSLLTSSEISP
SRFTGL--KRLSVITGPGSPSTAKASG-T-------------SLPTAQRRSLHKELVEAI
SQHHIDELPPPSQELLDEIEHLKQQRASPTVSD-EN----TTSDPGC-S--MNDQRHLGE
----QETDNKKEDSSILWIKEIQDLGEDTERAHSTLDEDLERWLQLPEE-NKGLSNLPE-
GSAR-ETDTKDQAVGEKKRKGEESIRLERRKSESFL-GTS-------EE-DELKPCFWKR
LGWSE------P----------------SRIIVLDQSDLSE-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---

--MSRAVHLPVPCPVQLGTIRNDSLEAQLHEYVKQGNYVKVKKILKKGIYVDAVNSLGQT
ALFVAALLGLAKLVDVLVDYGSDPNHRCFDGSTPVHAAAFSGNQWILSKLLDAGGDL RLH
DQKGRNPQTWALTAGKERSTPM--VEFMQ-RCASHMQAII-QGFS-YDLLKKIDSPQRLI
CSPPWFGGLMQGNP---NGSPNRL--LKAGVISAQNIYSFGFGK----------------
------------------------------------FYLTGG-TQLAYLGSLPVIGEKEV
IQADDEPTFSFFSGPHMVMTNLVWNGSRVTVKELNLP-THPHCSRLRL ADLLIAEQEHSS
KLRHPHLLQLMAVCLSQDLEQTRLVYERITVGTLFSILHERRSQFPMLHMEVIVHLLLQI
SDALRYLHSRGFIHRSLSSYAVHIVSPGEARLTNLEYMMES-RDGGI--HRDLTRVPLPA
QLYNWAAPEVILQKAATVTSDIYSFSVMIQEILT--DNIPWNGLDGSVIKEAIVLGNYLE
ADVRLPKPYYD-IVKSGLQVKQRDRTMNLQDIRYILKNDLK----DFIGAQRTQPTESSR
VQRYELHPDVNVHLGLTSEHPKETPDLEIKEL----------KET-GSQPHSPRSHFSPT
EK--RAPDPQAPGPSLTAKETQNQDT---------------LSDPFVA-EEASSP---SL
GQASLCSFEINEIYLG-CLNWKDDKEEEPPGAASSLEGNRPN-QVDE-LKSMEEE-----
-LDKME-REACCFCDEGE-----SSSEADTVLSFEDWDWQNASLGSLSLPEPTRGAKGNV
SNRSMTE-EYISKCVLNLKIAQTLMHQNANLLRNAQQKMDKLEMIQKEQE--ECSSLWVT
-------S------REFANVYS---LPSAVGPPALSYIPPVMQQSGGQQP-DKRGNCPPL
ERFPR-------------------------------------------------TLLTLC
GPGKQNTGKQFQPAQGAKDSLERS-RNQNTSSQGRP-REFSTQAKVTQ-LNSA--LFTVS
SHQQGPPGSSSPHWDATR---ISVESVSSEIYNAKSR--------NNKDDGEVHSKWKME
VREMAEKAATGQLTVPPWHPQSSLTSESEA----ENEPHPLLPPP--------------I
RGSENTDWQ---------QVVEYRREVDDPGGN--GKFDKVDNSDGDRDQCG-RQPGPPS
FTSIRHLSPR------------ENEQPEHSEA------FQASSDASVLIEKC----YST-
------------------------------------------SS--PI-EQDFEGIQGAF
AQ------PQASG-EEKFQVTKIL-GKNAEILTQSHFQPIRSTEGE----QEETLKES--
-PKEPKEKDISLTDIQDLSSISYEQDSSFKEASCKTPKINHAPTSVSTPLSP---GSISS
AASRYKDCLENITFQ-VKTGSTSCRDSQESIQTLSDKFTTIQ-EKAKSLDSLLTSSETPA
SRLTDV--KRLSAFTGAGSSSIAKASD-I-------------SSQTTQRRSLP--KVEVI
SQHRIDELPPPSQELLDEIEQLKQQQASSSVLH-EN----TAGDPGI-T--ANDKSHLEE
----QETGGNKEDSSILWTKETEDLGEDTERAHSSLDEDLERWLQPPEE-SVELQDLPK-
GSAR-ETNTKDQEVGEKKIKREESIKAERRRSESFL-GTS-------EE-DEVKPCFWKR
LGWSE------P----------------SRIIVLDQSDLSD-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---

--MSRAVQLPIPCPVQLGSLRNDSLEAQFHEYVKQGNYVKVKKILKKGIYVDTVNSLGQT
ALFTAALLGLPKLVDVLVDYGSDPNHRCFDGSTPVHAAAFSGNQWILSKLLDAGGDLRLH
DEDGKKPQSWALSAGKERSTAI--LEFMH-RCASHMQAII-QGFS-YDLLKRIDSPQRLI
SSPSRFGNLIHGNP---DSSPNRL--LKSGVVSSKNIYSFGFGK----------------
------------------------------------FYLTGG-TQLAYLGSLPVIGEKEV
IQADDEPTFSFCSGPYMVMTNLVWNGSRVTVKELNFA-THQNCSKLRFADLLIAEQEHSS
KLRHPHLLQLMAVCLSQDLEKTRLVYERINIGSLYSILHERRSQFPVLHMEVIVHLLLQI
NDALRYLHSRGFVHRSLSSYAVHIVSAGEARLTNLEYMIES-QDGGA--HKDLTRVPIPA
LLYSWSAPEVILQKAATVKSDIYSFCIIIQETLT--DTLPWNGLEGSVIKEAVVLGNHLE
ADARLPKTYYD-IVKTGIQVKQKDRTMNLQDIRYILKNDLK----DLIEAQRTHPIENTN
VQKYKKHHDINIYFGMTSENKREALDLEFREL----------KET-GCQPDSPQSPSALP
EK--TALDCEVLNHSMAAKETESRDTLS-------------------ELARACSP---SR
GEESLCSFEINEIYSC-YLDMCDDDLGGITTSEMSV-GNGRN-LGEE-TKSITGE-----
-SPEIN-KAARSDYGEDD-----TLSEAGTESSFEHWEPLSENFTS-HIQEVPREAKPDL
SSKSRTE-QYISKCVLNLKISQTLMQQAAESLRNAEQKIGTLEVMRRRQEQ-QMSSSWAA
-------L------SFCVRGHDPLVLWAAAGPPAKCYIPPSVQVLA-QQP-GCVDHFQNL
LKTARAMREFQGMGLEGSVGQR-HKRKGGHSWKPF---ESVPEESIGDQAEKNPQPLSFC
GTNRLCTNVKLQYPQGDDENLEIT-TRNQ-------------------------------
-----------------ETVRMNVDSISSEFYNSKTR--------GD-DSREARLKWTTE
VKEMAEKAASGQLGSLLWYPQSSLISDSETEN----DSESVRQPF--------------P
REPLHSDCP----------GADPPREHDDPSGKD-QGEKTILNDQDSEDSEG-KETGFQN
VTGTRHHLPR------------KKKHPEHGGA------FHKHSDSPEGIEKF----CSEH
SMESPRSVDSSE---DVTDEFLTPDHDYFYSSTVQEHLEAKTFH--E--ESDLEVTQEVC
SDQKQDSGKMCSGGERFQVIEKIL-GNKSECVTELQFTPISLG-------EEETLEES--
-SKELKEKDISLVDIQELSSISWEQGCSYKEIPCKTPRTSHGPTSVSTPVSP--AGAASS
VINLCKDCSEGSSSQ-PNIQATSCWDSQDSIQTMSNTFMTASHEKGQRTDSFSFPSEMPS
FGLTDHLQDNLSTFSGSSIIKAKTESV-K-------------LFPATQQSRFHKERADSP
SLECTDELPLPSQELLDEIA--------------------------------LDQRHLEE
----KLIENKGEDGSILWTKETLYLTEETDRAHSTLDEELERWLQPSEK-SQELQGLTK-
SPAR-ETSLTDQEVGEKKKKGEEGTKAERRKIDCFP-GSP-------EDQEELKPGLWHR
LGWTQ------P----------------SRIIVLDQSSTSD-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---

--MSRAVRFPVPCPVQLGSLRNDTLEALLHEYVKQGNYVKVKKILKKXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXRCFDXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX--MVEFMQ-RCATHMQAII-QGFS-SDLLKKVDSPQRLI
CSPPRFGGFMQGNS---NGSPNRL--LKAGVISAQNIYSFGFGK----------------
------------------------------XXXXXXXXXXXX-XXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXLVWNGSRVSVKELNLP-THPHCSRLRLADLLIAEQEHSS
KLRHPYLLQLMAVCLSQDLEKTRLVYERITVGTLFSVLHEQRSQFPILHMEVIVHLLLQI
SDALRYLHSRNFIHRSLSSYAVHIVSTGEARLTNLEYMMEX-XXXXX--XXXXXXXXXXX
XXXXXXXXXXILQKAATVKSDIYSFSMIIQEILT--DNIPWNGLDGSVVKEAVVLGNYLE
ADIRLPKPYYD-IVQSGIQVKQKDRAMNLQDIRYILKNDL----KDFVGAQRTQPTETPR
IQRYELHPDVDVYLGLTSEHPKEPPDLEIKEL----------KET-GSLHHALRSPCSPT
EKA--ELDLQGPDPSLTAKDTQNQDV--------------ASLV-SSVAEETKSA---ST
GQASLRSFESNEIYSS-CLDMGDEKEEEPPGLGSSLWGDNPH-QVVE-LKSMEEE-----
-LDKMK-REACCFCNEDE-----SSLKSDTELSIEDWVWQNSSFSSLNLQMSTREAKGNV
SNKSM-TDMYISKCVLNLKISQTLMHQFNDTLRNVEQKVNELEMIQKEQEQ--QRSLWAS
-------S------REFANVPF-----LAIGPPSLTYVPPAMHLLVGRQP-DTSGNSETL
ARS--------------------------------------------------LTLPALC
GFRKQNTGKQFQPSQGAKNSLERR-MNQNTKSQERS-RDFGSPAKVTQ-LISE--LYMVS
SHLHGPPGSPSPGQDSTR---ICMESVSSEICNPKLR--------N-NXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----XXX--XXX-----------------X
------XXX---------XXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXX-XXXXXXX
XXXTRHLSPR------------KNEQSEDIAA------FQASSASSVIIEKS----YSDQ
SXXXXXXXXXXX---XXXXXXXXXXXXXXXXXXXXXXXXXXTSS--PI-EEDSEGTQGAF
AQ------LQGSX-XXXXXXXXXX-XXXXXXXXXXXXXXXXXAEGE----QEETLKES--
-PKELKEKDISLTDIQDLSSISYEQDRSFKETSSKTPRISHAPTSVSTPLSS---XXXXX
XXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXX
XXXXXX--KRLSAFTGAGSSVT-KAPATS-------------LP-ATQRRSLPK--VEAI
SQHHIDELPPPSQELLDEIELLKQQQASSTVLDK-----STASDPDI-T--AKXXXXXXX
----XXXXXXXXXXXXXXXXXXXXXXXXXXXAHSTLDEDLERWLQP-EE-SMQLQDLPE-
GSAR-ETNTKDQEVGEKKKKGKEGVTPERRKSERFL-GTP-------EE-DELKPCFWKR
LGWSE------P----------------SRIIVLDQSDLSD-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---

--MSRAVPLPLPCPVQLGTLRNDSLEAQLHEYVKQGNYLKVKKILKKGIYVDAVNNLGQT
ALFVAALLGLRKLVDVLVDYGSDPN-----------------------------------
-----------------------IVEFMQ-RCALHMQAII-QGFS-YDLLKKIDSPQRLV
YSPPWFGSLVQGNP---NGSPNRL--LKAGVISAQNIYSFGFGK----------------
------------------------------AMPWFQFYLTGA-TQIAYLGSLLVIGEKEV
IQADDEPTFSFFSGPYMVMTNLVWNGSRVTVKELNLP-THPHCSKLRLADLLIAEQEHSS
KLRHPYLLQLMAVCLSQDLEKTRLVYERITIGTLFSVLHERRSQFPVLHMEVIVHLLLQI
SDALRYLHSQGFIHRSLSSYAVHIVSPGEARLTNLEYMLES-KDRGE--QRDLTRVPLPT
QLYNWAAPEVILQKAATVKSDIYSFSMIIQEILT--DDIPWNGLDGSVIKEAIVLGNYLE
ADVRLPKPYYD-IVKLGIHIKQKDRTMNLQDIRYILKNDL----KDFTGTQRTQPTESPR
VQRYGLHPDVNVYLGLTSEHTRETPDMEIIEL----------KEM-GSQPHSPRVHSL-F
TEG--TLDPQAPDPCLMARETQNQDA--------------PCPT-PFMAEEASSP---ST
GQASLCSFEINEIYSG-CLTLEDDI-EEPPGAASSLEADGPN-QVDE-LQSMEEE-----
-LDKME-REACCFCSEDE-----SSSKAETEYSFEDWDWQNGSLSSLSLPESTREAKSNL
NNRSMAEEYLISKCVLDLKIMQTIMHENDDRLRNIEQILDEVEMKQKEQEE--RMSLWAT
-------S------REFTDVYN---LPPAVGPPSLNYIPPVLQLSGGQQP-DTSGKCPTL
PRFPRM-------------------------------------------------LLTLC
DPGKQNTDEQFQGTQGVKGSLERS-RIQNTSSRGKP-RESTAQAKATQ-FDSA--LFTLS
SHWQGPSASPNSHWDSTR---MSVDPVSSEIYNAESR--------N-KDDGEVHLKWKME
VKEMAEKAATGQLTVPPWHPQSSLTLESEA----ENEPDALLQPP--------------I
GSPENTDWQ---------RVIEYHRENDEPRGNA--KFDNTGNNDCDSDQHD-RQPRPGS
FTNIRHPSPR------------QKEQPEYSEA------FQASSDSLVAVEKS----YSHQ
SMQSTCSPESSE---DITDEFLTPDDEYFYSSTAQENLALETSS--PI-EEEFEGIQGAF
AQ------PQVSG-EEKFQMRKIL-GKNAEILPRSQFQPIRSTEDE----QEETSKES--
-LKELKEKDISLTDIQDLSSISYEPDSSFKEASCKTPKINHAPTSVSTPLSP---GSVSS
AASQYKDCIESITFQ-VKTESASCWNSQEFIQTLSDEFISVR-ERAKKLDSLLTASETCP
SRLPGL--KRLSSFIGAGSSSPVKACDSS-------------PPHATQRRSLPK--VEAF
SQHHIDELPPPSQELLDEIELLKQQQGSSTVLHE-----NTASDAGG-T--ANDQRHLEE
----QETDSKKEDSSMLLSKETGDLGEDTERAHSTLDEDLERWLQPPEE-SMELQDLPK-
GSER-EINIKDQEVGEDKRKREDSITPERRKSESVL-GTS-------EE-DELKPCFWKR
LGWSE------S----------------SRIIVLDQSDLSD-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---

------------------------------------------------------------
----------MKLVDVLVDYGSDPNHRCFDGSTPVHAAAFSGNQWILSKLLDAGGDLRLH
DERGQNPQTWALTAGKERSTQ--IVEFMQ-RCASHMQAII-QGFS-YDLLKKIDSPQRLV
YSPPWFGGLVQRSP---NGSPNQL--LKAGVISAQNIYSFGFGK----------------
------------------------------------FYLTGA-TQIAYLGSLPVIGEKDV
VQADDEPTFSFFSGPYMVMTNLMWNGYRVTVKELNLP-THPHCNKLWLADLLIAEQEHSS
KLRHPYLLQLMAVCLSQDLKKTRLVYERITIGTLFSVLHEQRSHFPVLHMEVIVHLLLQI
SDALRYLHFRGFIHRSLSSYAIHIISPGEARLTNLEYMMES-QDGGV--QRDLTQVPLPT
QLYNWAAPEVILQKAATVKSDIYSFSMIMQEILT--DDIPWSGLDGSVIKEAIVLGHYLE
ADVRLPKPYYD-IVKSGIHIKQKDRTMNLHDIRYILKNDL----KDFTGAQRTQPTESPR
VQRYGLHPDVNVYLGLTSEHPKETPDMEIKEL----------KEM-GSQPHSPRVHSL-F
TEG--TLDPQTPDAYLMARETQNQDA--------------PCPA-PFMAEEASSP---ST
GQASLCSFEINKIFSG-CLTLEDDI-EEPPGAASPFEADRSN-RVDE-LKSMEEL-----
-LDKME-REACCFWSEDK-----SSSEAGTEHSFEEWDWQNGSLSSLSLPEPVREAMSNL
NNRFRTEEYYLSKSVLDLKIMQTVMQENDVRLRNIEQILDEVEMKQKEQEE--HMSLWTA
-------S------RKFANVYN---LPPAVGPPSLNYIPPVLQLSGGQQP-DASGNCPTL
ARFP---RDFQG----GHLGKR-SRKRSGCGWKHF---TQVSEVITGDQSEMSHQLPILC
NPGKQNTDQQFQPTQGAKDSLERR-SIQNTTKEDLE-SPLTKPKPH----DLI--VHSSL
RQATSRDLLTGSHQDSTR---MSMEPVSSEIYNAESR--------N-KDDGEVHLKWK--
------------------------------------------------------------
------------------------------------------------------------
--SISHPSPG------------QNEQPEHSEA------FQASSDALVAIKKS----YSNE
STQSTCSPQSSE---DIIDEFLTSDHEYFYSSAAQENLALETSS--PI-EEDFEGIQGAF
AQ------PQVSG-EEKFQMIKIL-GKNAEILPRSQFQPVRSTEDE----QEEMLKES--
-PKKLKEKDISLTDIQDLSSISCEPDSSFKEASCKTPKINHAPTSVSTPLSP---GSVSS
AASRYKDCLESMTLQ-VKTGSASCWNTQESIRTLSDEFTSVR-ERAKRLDSLLTSSETPP
SRFAGL--KRLSSFTGSGSPRLAKACDTS-------------LPHATQRRSPPKELVEAI
SQHHIDELPPPSQELLDEIELLKQQQNSSTVLHE-----NTASDAGV-T--TNDQRHLEE
----QETDSKKEDSSMPWSKEAEDLGEDTERAHSTLDEDLERWLQPPEE-SMELQDLPK-
GSER-ETNTDDQEVGEEKRKREDSITPERRKSESVL-GTS-------EE-DELKPCFWKR
LGWSE------P----------------SRIIVLDQSDLSD-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---

--MSRAVHLLLPCPVQLGSLKNDSLEGQLHEYVKQGNYVKVKKILKKGVYVDAVN S LGQT
ALFVAALLGLTKLVDVLVAHGSDPNHRCFDGSTPVHAAAFSGNQWILSKLLDAGGDLRLH
DEKGQNPQTWALAAGKERSTPM--VEFMQ-RCASHMQAII-QGFS-YDLLKKVDSPQRLV
CSPPWFGGLMQGNS---NGSPNRL--LKAGVISAKNIYSFGFGKAA--------------
-----------------------------FFLFWFQFYLTVG-TQLAYLGSLPIIGEKEV
IQADDEPTFSFFSGPYMVMTNLVWSGSRVTVKELNLQATQQRCSRLRLADLLIAEQEHSS
KLRHPHLLQLMAVCLSQDLEKTRLVYERITIGTLFSVLHERRSQFPVLHMEVIVHLLLQI
SDALRYLHSRGFIHRSLSSYAVHIVSPGEARLTNLEYMLES-QDGGV--QRDLTRVPLPS
QLYNWAAPEVILLKAATVKSDIYSFSMIVQEMLT--DNIPWNGLDGSVIKEAIVLGNYLE
ADVRLPKPYYD-IVKSGIQIKQKDRTMNLQDIRYILKNDLQ----EFIGVQRTQPPESPR
VQRCEPHPDSSVYLGLTSEQPKETFNLEIKEL----------KEMXXXXXXXXXXXXXXX
XXX-XXXXXXXXXXXXXXXXXXXXXX--------------XXXXXXXX-XXXXXX---XX
XXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXX---X--XXXXXXX-----
-XXXXX-XX-XXXXXXXX-----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXX-EYISKCVLNLKISQVLMQQNTERLTRVEQQLLEVEVAHRELE----ERRWEA
-------L------QKLSNVLS---LPKAVGPPSLIYIPPIIQLPGSQQP-DTTDNCPSL
ARSPR-------------------------------------------------AQVALG
SPGKDNTGEQFEHAQEARVNLGRS-QDQNTTSQGGT-KESNNHAKVTP-LNSK--PLIMS
SHPQGPACQD-----S---ARISVEAMPSEVSTAKSR--------NKEDDGRVHLRWKME
VKAIAEKAATGQLTVPPWHPQS-LTLECGA----ESKPDPLPQPP--------------L
RGPENMNSQ---------RVVDYHREPDKPGGF--GKFNKLNNRDC--DQHG-RQTGPCS
FTGIRHVSPE------------ENKQPEHREA------LKASSEASAVIEKS----DSDK
SVQSTCSPETSE---DLTDEFLTPDHEYFYSSAARENLALEISS--PIEDL---EVQGAL
AQ------SQVSD-EEKF----HF-GKNAEILIKSPFQLKQSTGGE----QEETLKEP--
-PKELKEKDISLTDIQDLSSITCEQDGSVKEVLCKTPRISHAPTSVSTPLSPQRAGSASS
AANQYKNCLEDITFQ-VETVSSCCQNNQESVRTLSAKSATVR-ERAKSLESLFPSCETSP
SRLTAL--KRSFTYNRTSSSSIAKAPG-T-------------SPQAVQRRSLP--KVEAI
SQHHIDELPPPAQEFLDEIEHLKQQQASSTVLHTAHDPVITANGRGG-S--SNNQKHLEE
----QETDSKKKDGSMHWTKESQDLGEDTERAHSSLDEDLERWLQPPEE-CIELQALPK-
GSTR-ETNTKDQEVDGKKRKGDESIKSEKRKSESFL-GTS-------EE-DERKP-FWKR
LGWSE------P----------------SRIIVLDQSDLSD-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---

--MSRAVPLPLPCPVQLGTLRNDSLEAQLHEYVKQGNYLKVKKILKKGIYVDAVNNLGQT
ALFVAALLGLRKLVDVLVDYGSDPNHRCFDGSTPVHAAAFSGNQWILSKLLDAGGDL RLH
DERGQNPKTWALTAGKERSTQ--IVEFMQ-RCALHMQAII-QGFS-YDLLKKIDSPQRLV
YSPPWFGSLVQGNP---NGSPNRL--LKAGVISAQNIYSFGFGK----------------
------------------------------AMPWFQFYLTGA-TQIAYLGSLLVIGEKEV
IQADDEPTFSFFSGPYMVMTNLVWNGSRVTVKELNLP-THPHCSKLRL ADLLIAEQEHSS
KLRHPYLLQLMAVCLSQDLEKTRLVYERITIGTLFSVLHERRSQFPVLHMEVIVHLLLQI
SDALRYLHSQGFIHRSLSSYAVHIVSPGEARLTNLEYMLES-KDRGE--QRDLTRVPLPT
QLYNWAAPEVILQKAATVKSDIYSFSMIIQEILT--DDIPWNGLDGSVIKEAIVLGNYLE
ADVRLPKPYYD-IVKLGIHIKQKDRTMNLQDIRYILKNDL----KDFTGTQRTQPTESPR
VQRYGLHPDVNVYLGLTSEHTRETPDMEIIEL----------KEM-GSQPHSPRVHSL-F
TEG--TLDPQAPDPCLMARETQNQDA--------------PCPT-PFMAEEASSP---ST
GQASLCSFEINEIYSG-CLTLEDDI-EEPPGAASSLEADGPN-QVDE-LQSMEEE-----
-LDKME-REACCFCSEDE-----SSSKAETEYSFEDWDWQNGSLSSLSLPESTREAKSNL
NNRSMAEEYLISKCVLDLKIMQTIMHENDDRLRNIEQILDEVEMKQKEQEE--RMSLWAT
-------S------REFTDVYN---LPPAVGPPSLNYIPPVLQLSGGQQP-DTSGKCPTL
PRFPRM-------------------------------------------------LLTLC
DPGKQNTDEQFQGTQGVKDSLERS-RIQNTSSRGKP-RESTAQAKATQ-FDSA--LFTLS
SHWQGPSASPNSHWDSTR---MSVDPVSSEIYNAESR--------N-KDDGEVHLKWKME
VKEMAEKAATGQLTVPPWHPQSSLTLESEA----ENEPDALLQPP--------------I
GSPENTDWQ---------RVIEYHRENDEPRGNA--KFDNTGNNDCDSDQHD-RQPRPGS
FTNIRHPSPR------------QKEQPEYSEA------FQASSDALVAVEKS----YSHQ
SMQSTCSPESSE---DITDEFLTPDDEYFYSSTAQENLALETSS--PI-EEEFEGIQGAF
AQ------PQVSG-EEKFQMRKIL-GKNAEILPRSQFQPIRSTEDE----QEETSKES--
-LKELKEKDISLTDIQDLSSISYEPDSSFKEASCKTPRINHAPTSVSTPLSP---GSVSS
AASQYKDCIESITFQ-VKTESASCWNSQEFIQTLSDEFISVR-ERAKKLDSLLTASETCP
SRLPGL--KRLSSFIGAGSSSLVKACDSS-------------PPHATQRRSLPK--VEAF
SQHHIDELPPPSQELLDEIELLKQQQGSSTVLHE-----NTASDAGG-T--ANDQRHLEE
----QETDSKKEDSSMLLSKETGDLGEDTERAHSTLDEDLERWLQPPEE-SMKLQDLPK-
GSER-EINIKDQEVGEDKRKREDSITPERRKSESVL-GTS-------EE-DELKPCFWKR
LGWSE------S----------------SRIIVLDQSDLSD-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---

--MSRAVRLPVPCPVQLGTLRNDSLEAQLHEYVKQGNYVKVKKILKKGIYVDAVNSLGQT
ALFVAALLGLRKFVDVLVDYGSDPNHRCFDGSTPVHAAAFSGNQWILSKLLDAGGDL RLH
DERGQNPKTWALTAGKERSTQ--IVEFMQ-RCASHMQAII-QGFS-YDLLKKIDSPQRLV
YSPSWCGGLVQGNP---NGSPNRL--LKAGVISAQNIYSFGFGK----------------
------------------------------------FYLTGA-TQMAYLGSLPVIGEKEV
IQADDEPTFSFFSGPYMVMTNLVWNGSRVTVKELNLP-THPHCSKLRL ADLLIAEQEHSS
KLRHPYLLQLMAVCLSQDLEKTRLVYERITIGTLFSVLHERRSQFPVLHMEVIVHLLLQI
SDALRYLHFQGFIHRSLSSYAVHIISPGEARLTNLEYMLES-EDRGV--QRDLTRVPLPT
QLYNWAAPEVILQKTATVKSDIYSFCMIMQEILT--DDIPWNGLDGSVVKKAVVLGNYLE
ADVRLPKPYYD-IVKSGIHVKQKDRTMNLQDIRYILKNDL----KDFTGAQRTQPTESPR
VQRYRLHPDVNVYLGLTSEHPRETPDMEIIEL----------KEM-GSQPHSPRVHSL-F
TEG--TLDPQAPDPCLMARETANQDA--------------PCPA-PFMAEEASSP---ST
GQPSLCSFEINEIYSG-CLILEDDI-EEPPGAASSLEADGPN-QVDE-LKSMEEE-----
-LDKME-REACCFGSEDE-----SSSKAETEYSFDDWDWQNGSLSSLSLPESTREAKSNL
NNMSTTEEYLISKCVLDLKIMQTIMHENDDRLRNIEQILDEVEMKQKEQEE--RMSLWAT
-------S------REFTNAYK---LPLAVGPPSLNYIPPVLQLSGGQQQ-DTSGNYPTL
PRFPRM-------------------------------------------------LPTLC
DPGKQNTDEQFQCTQGAKDSLETS-RIQNTSSQGRP-RESTAQAKATL-FNSA--LFTLS
SHRQGPSASPNCHWDSTR---MSVEPVSSEIYNAESR--------N-KDDGKVHLKWKME
VKEMAKKAATGQLTVPPWHPQSSLTLESEA----ENEPDALLPPP--------------I
RSPENTDWQ---------RVIEYHRENDEPRGNG--KFDKTGNYDCDSDQHG-RQPRPGS
FTSIRHPSPR------------QKEQPEHSEA------FQASSDTLVAVEKS----YSHQ
SMQSTCSPESSE---DITDEFLTPDDEYFYSSTAQENLALETSS--PI-EEDFEGIQGAF
AQ------PQVSG-EEKFQMRKIL-GKNAEILPRSQFQPVRSTEDE----QEETSKES--
-PKELKEKDISLTDIQDLSSISYEPDSSFKEASCKTPKINHAPTSVSTPLSP---GSVSS
AASQYKDCLESITFQ-VKTEFASCWNSQEFIQTLSDDFISVR-ERAKKLDSLLTSSETPP
SRLTGL--KRLSSFIGAGSPSLVKACDSS-------------PPHATQRRSLPK--VEAF
SQHHIDELPPPSQELLDEIELLKQQQGSSMVLHE-----NTASDAGG-T--ANDQRHLEE
----QETDSKKEDSSMLLSKETEDLGEDTERAHSTLDEDLERWLQPPEE-SVELQDLPK-
GSER-ETNIKDQKVGEEKRKREDSITPERRKSEGVL-GTS-------EE-DELKSCFWKR
LGWSE------S----------------SRIIVLDQSDLSD-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---

------------------------------------------------------------
------------------------------------------------------------
-----------------------MVEFMQ-RCASHMQAII-QGFS-YDLLKKVDSPHRLI
CSPPWFGGLMQGNP---NGSPNRL--LKAGVISAQNIYSFGFGK----------------
------------------------------------FYLTGG-TQLACLGSLPIIGEKEV
IQADDEPTFSFFSGPFMVMTNLVWNGSRVTVKELNLP-THPHCSRLRLADLLIAEQEHSS
KLRHPHLLQLMAVCLSQDLEKTRLVYERITVGTLFSVLHERRSQFPVLHMEVIVHLLLQI
SDALRYLHSRGFIHRSLSSYAVHIVSAGEARLTNLEYMMES-QDGGV--HRDLTRVPLPS
QLYNWAAPEVILQKAATVKSDIYSFSMIIQEILT--DNVPWNGLDGSVIKEAVVLGNYLE
ADVRLPKPYYD-IVKSGIQVRQKDRTMNLQDIQYILKNDL----KEFIGVQRTQPTESPR
VERYEPHPDVY--LGLTSEHPKDTLDLEIKEL----------KEM-GSPLHSPRGHSSPT
EEA--TLDPVTPEPSVMAQEAVHQPA--------------PSLA-HLVAEEARSP---ST
SQASLCSFEINEIYSG-CLNLGDGKEEETPGAASSPEGERPN-QADE-LQSMEEE-----
-LDKME-REAYCLCA-DK-----SSSETDPELSFGDWDWQNDSLSSPSLPESTREVQGPV
SNRSMTE-EYISKCVLNLKIAQTLMHQSADLLRDTQQEIGQLEVMHNEQE--ECRSLWEA
-------S------REFANVCR---SPSALGPPAPSYIPPAMHLSGGQQP-DTRGSCLTL
ARSPRTARDFQG----GHFGKR-PRKRSGCDWKPL---TQVSEESSGHQSETSHQ-TTLG
GSGKDNTGEQFQHTEGAKVSLDRS-RNQSTSSQGGS-RELNAQAKGTQ-LNSA--FFTVS
SHPRGASGSPSPSQDSTN---ISVEAVTNEICNAKS---------RNEDDGKVHLKWKME
VEAIAEKAATGQLTVPPWHPRSSLTLECEA----ENKPDPLLQPP--------------A
RGPENMNWQ---------RAVEYHRDKDEPAGNN--QFDRLDHSDCDQ--HS-RQPGPRS
FTSIRHLSLG------------ENEQPEYSEA------FQASSEASVVIEKS----YSDR
SVQSSCSPETSE---DITDEFLTPDHEYFYSSTVRENLDLETSS--PI--EDFEGVQGTL
AQ------PQVSG-EEKFH----L-GKNAETLTRSQFQPIQSTEGE----QEQALKKP--
-PKELKDKDISLIDIQDLSSITYEQDGSFKEVSSKTPKVTHAPTSVSTPLSP---GSASS
AASQYKDCLEDITFQ-VKTEATCCWNNQESIQTLSGKSATVR-ERARSLESLFPSTET-S
SRLTDV--KRLPVCPGACSSSIAIAKASD-----ISLHAF-------QKRSLPKELIEAI
SQHHIDELPPPSQELLDEIECLKQQQASSTALHE-----NTAHDPVI-T--ANDHKHLEE
----QETDSKKEDSSMLWTKETQDLEEDTERAHSTLDEDLERWLQPPEE-SVEPQDLPK-
--AL-Q-----------------G----------YC-SPPGNHFLLYPE-V---------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---

Query Results

"ENSGT00390000015123_0"

ENSGT00390000015123_0