Query Results 

------------------------------------------MA-QTPDGISCELRGEIT
RFLWPKEAELLLKTWLPQ-EGV---ERSHILALLRWRAYLLH-TCLPLRVACTFSYLEVQ
SMTLQETPPQVTFEL-ESLPELVLEFPGVATLEQLAQHVASAIKKVFPRSALGKLFRKPT
PPSMLARLE-RSSPSEST--APSSPCGGFLETYEALCDYNGFPFQEEIQWDVDTIYHRQG
CRQFNLGDFSHLGS----RDLALSVAALSYNLWFRCLSCVDMKLSLEVSEQILHMMGQSS
HLEELVLETCGLKG--------------DFVRRLAQALAGHS

PF13516 // ENSGT00390000014487_1_Domain_0 (343, 378)

CSGLRELSLAGNLLDDRG
M-------------AALSRHLEHRPGALRRLSLAQTGLTPR-------------------
-------GMRALGLALATNA-AFDSVLTHLDLSGNPGALGASEDNGGLYSFLS----RPN
FLMFLNLAGTDAALDT--------------------------------------------
LFAALSRGCCASLTHLDTSRNVFSRCKSRAA-----PAPLQLFLSRAETLRYLGLS---G
CKLPPEALRAVLDGLALNTHIRDLHLDLSACELRSAGAQVIQDLVCDAGVVSSLDLADNG
FGSDMVTLVLAIGRSRSLRHVALGRNFNVRCKETLDDVLHRIVQLMQDDDCALQSLSVAD
SRLKLGAGVLLRALGA

PF13516 // ENSGT00390000014487_1_Domain_3 (737, 760)

NP-NLTALDISGNAMGDTGAKML

ENSGT00390000014487_1_Linker_3_4 (760, 977)

AKALRVNTRLRSV---IWDRN
HTSALGLLDVA---QALEQN-HSLKAMPLPLNDVAQAQRSRPELTARAVHQIQACLLRNN
REDPTSSGRTSCLQPLNLVSEHSEQEVNELCQSVQEHMELLGCGSGPQSEAAVHQA----
-EDAIQNANFFLSILPILN----EAGNSPSHHWQLRQKLEALLGQVGEACHEDIQ-----
-------DFIQAILDT

PF16000 // ENSGT00390000014487_1_Domain_4 (977, 1292)

-RSLCPQMLQGPGWREQLEGILVGSKGL-----PELLPEQLLQD
AFVRLRDVRLSERQCRTLAESIVAQAVAGLSAARDRLVES----------LAQQVPVAIP
PALPAL-DGGEPSPLGPGAV------EGF--FFPEEKED-----------KKDESPLRKW
PEH------------NHCLHLVPFEHSAAE-----------------------EAEPEPE
LAAPGEDAE---------------PQ----------------------------------
------------------------------HHH---------------------------
------RPP---PGGPQVPPALPQE----GNGLSARVDEGVEEFFSKRLIQQDRLWAP--
EEEDPATEAGASPVPRTLRKKLGTLFAFKKPRSTRGPRPDLETSLG-VAARARKTTLGDL
LRPPARPGRGEEP------------GGAEG-GPSSPDPARRSRPRYTRESKAYSMILLPA
EEE---DTLNARPDKRRP---LERGDTEMAPSFEQRVQVMLQRIGVSRGGGSAEGKRKQS
KDGEIKKAGSDGDIMDSSTETPPISIKSRTHSVSADPSCRPGP---GVQGPESATWKTLG
QQLNAELRGRGWGQQDGPGPP-------SP---CPS------PNLRRASPAPDILGLPED
PCLGPRNEDGQL-RPRPLSAGRRAVSVHEDQLQAPAERP----L----RLQRSPVLKRRP
KLEAPP-SPS-LGSGLGTEPLPPRPTEPS--S-P------EQSPPSPATDQ-----RGGG
PN---P-----------

------------------------------------------MA-QTPDGISCELRGEIT
RFLWPKEVELLLKTWLPG-EGA---VQNHVLALLRWRAYLLHTTCLPLRVDCTFSYLEVQ
AMALQETPPQVTFEL-ESLRELVLEFPGVAALEQLAQHVAAAIKKVFPRSTLGKLFRRPT
PASMLARLE-RSSPLEST--GPCSPCGGFLETYEALCDYNGFPFREEIQWDVDTIYHRQG
CHHFSLGDFSHLGS----RDLALSVAALSYNLWFRCLSCVDMKLSLEVSEQILHMMSQSS
HLEELVLETCGLRG--------------DFVRRLAQALAGHS

PF13516 // ENSGT00390000014487_1_Domain_0 (343, 378)

SSGLRELSLAGNLLDDRG
M-------------AALSRHLERCPGALRRLSLAQTGLTPR-------------------
-------GMRALGRALATNT-AFDSALTHLDLSGNPGALGSSEDSGGLYSFLS----RPN
VLSFLNLAGTDTALDTVRGCSVGGWMTD------RADWRAGQGGL-G-PPAGAANSLPPQ
LFAALSRGCCTSLTHLDASRNVFSRTKSRAA-----PAALQLFLSRARTLRHLGLA---G
CKLPPDALRALLDGLALNTHLRDLHLDLSACELRSAGAQVIQDLVCDAGAVSSLDLADNG
FGSDMVTLVLAIGRSRSLRHVALGRNFNVRCKETLDDVLHRIVQLMQDDDCPLQSLSVAE
SRLKLGASVLLRALA

PF13516 // ENSGT00390000014487_1_Domain_3 (736, 760)

TNP-NLTALDISGNAMGDAGAKLL

ENSGT00390000014487_1_Linker_3_4 (760, 977)

AKALRVNSRLRWAGSEGWDQR
AGG-AGLNEAEQMESVVWDR-NHTSAMPLPLNDVAQAQRSRPELTARAVHQIQACLLRNN
RADPASSDHTTCLQPLGLVSDPSEQEVNELCQSVQEHVELLGCGAGPQGEAAVHQA----
-EDAIQNANFSLSILPILY----EAGSSPSHHWQLGQKLEGLLGQVGEVCRQDIQ-----
-------DFTQATLDT

PF16000 // ENSGT00390000014487_1_Domain_4 (977, 1415)

ARSLCPQMLQGSSWREQLEGVLAGSRGL-----PELLPEQLLQD
AFTRLRDMRLSIT--GTLAESIVAQALAGLSAARDQLVRGRCAHTFVTNGIMAEALPAI-
----F--DGGEPGLLEPGEL------GGL--FFPEEEKEE--------EEEKDDSPPQKW
PEL------------SHGLHLVPFIQSAAE-----------------------EAEPEPE
LAAPGEDAE---------------PQAGPSARGSPSPAAP---GPPAAPLPRMDL----P
PAGQ-P--------LRHPTR-ARPRPR-RQHHH---------------------------
------RPP---PGGPQVPPALPQE----GNGLSARVDEGVEEFFSKRLIQQDRLWAP--
EEDPAT-EGGATPVPRTLRKKLGTLFAFKKPRSTRGPRPDLETSPG-AAPRTRKTTFGDL
LRPPTRPSRGEEP------------GGAEG-DTSSPDPARRSRPRYTRDSKAYSMILLPA
EEE---ATLGARPDKRRP---LERGETELAPSFEQRVQVMLQRIGVSRGSGGAEGKRKQV
KGR----WHAVGDIMDSSTEAPPISIKSRTHSVSADPSCRPCP---GSQGPESATWKTLG
QQLNAELRSRGWGQQDGPGPP-------SP---GQS------PSPCRTSPSRDSLGLPED
PCLGPRNEDGQL-RPRPLSAGRQAVSVHEDQLQAPAERP----L----RLQRSPVLKRRP
KLEAPP-SPS-LGSGLGTEHLPPQPTEPS--S-P------EQSPPSPATDQ-----RGGG
PS---P-----------

------------------------------------------MAQ-TPDGISCELRGEIT
RFLWPKEVELLLKTWLPG-EGA---VQNHVLALLRWRAYLLHTTCLPLRVDCTFSYLEVQ
AMALQETPPQVTFEL-ESLRELVLEFPGVAALEQLAQHVAAAIKKVFPRSTLGKLFRRPT
PASMLARLE-RSSPSEST--DPCSPCGGFLETYEALCDYNGFPFREEIQWDVDTIYHRQG
CRHFSLGDFSHLGS----RDLALSVAALSYNLWFRCLSCVDMKLSLEVSEQILHMMSQSS
HLEELVLETCSLRG--------------DFVRRLAQALAGHS

PF13516 // ENSGT00390000014487_1_Domain_0 (343, 378)

SSGLRELSLAGNLLDDRG
M-------------TALSRHLERCPGALRRLSLAQTGLTPR-------------------
-------GMRALGRALDTNA-AFDSTLTHLDLSGNPGALGASEDSGGLYSFLS----RPN
VLSFLNLAGTDTALDTVRGCSVGGWMTG------RADWRAGRGGL-G-PPASVANSLPPQ
LFAAVSRGCCTSLTHLDASRNVFSRTKSRAA-----PAALQLFLSRARTLRHLGLA---G
CKLPPDALRALLDGLALNTHLRDLHLDLSACELRSAGAQVIQDLVCDAGAVSSLDLADNG
FGSDMVTLVLAIGRSRSLRHVALGRNFNVRCKETLDDVLHRIVQLMQDDDCPLQSLSVAE
SRLKLGASVLLRALA

PF13516 // ENSGT00390000014487_1_Domain_3 (736, 760)

TNP-NLTALDISGNAMGDAGAKLL

ENSGT00390000014487_1_Linker_3_4 (760, 977)

AKALRVNSRLRWAGSEGWDQR
AGG-AGLNEAEQMESVVWDR-NHTSAMPLPLNDVAQAQRSRPELTARAVHQIQTCLLRNN
RADPASSDHTTRLQPLGLVSDPSEQEVNELCQSVQEHVELLGCGAGPQGEAAVRQA----
-EDAIQNANFSLSILPILY----EAGSSPSHHWQLGQKLEGLLRQVGEVCRQDIQ-----
-------DFTQATLDT

PF16000 // ENSGT00390000014487_1_Domain_4 (977, 1415)

ARSLCPQMLQGSSWREQLEGVLAGSRGL-----PELLPEQLLQD
AFTRLRDMRLSIT--GTLAESIVAQALAGLSAARDRLVES----------LAQQATVTVP
PALPAP-DGGEPSLLEPGEL------EGL--FFPEEK-E-E-------EKEKDDSPPQKW
PEL------------SHGLHLVPFIHSAAE-----------------------EAEPEPE
LAAPGEDAE---------------PQAGPSARGSPSPAAP---GPPAGPLPRMDL----P
LAGQ-P--------LRHPTR-ARPRPR-RQHHH---------------------------
------RPP---PGGPQVPPALPQE----GNGLSARVDEGVEEFFSKRLIQQDRLWAP--
EEDPAT-EGGATPVPRTLRKKLGTLFAFKKPRSTRGPRTDLETSPG-AAPRTRKTTFGDL
LRPPTRPSRGEEP------------GGAEG-DTSSPDPARRSRPRYTRDSKAYSMILLPA
EEE---ATLGARPDKRRP---LERGETELAPSFEQRVQVMLQRIGVSRGSGGAEGKRKQV
KGR----WHAVGDIMDSSTEAPPISIKSRTHSVSADPSCRPGP---GSQGPESATWKTLG
QQLNAELRSRGWGQQDGPGPP-------SP---GQS------PSPCRTSPSPDSLGLPED
PCLGPRNEDGQL-RPRPLSAGRRAVSVHEDQLQAPAERP----L----RLQRSPVLKRRP
KLEAPP-SPS-LGSGLGTEPLPPQPTEPS--S-P------ERSPPSPATDQ-----RGGG
PN---P-----------

------------------------------------------MAQPSDGGISCELQGEIT
RFLWPKEVELLLKTWLPQ-EGA---ATSHVLALLRWRAYLLH-TCLPLRVDCTFSYLEVQ
AMALQEMPPQVTFEL-ESLPELVLEFPGVAALEQLAQHVAAAIKKVFPRSTLGKLFRKPT
PASMLERLE-RSHPLVST--GPSSPCGGFLETYEALCDYNGFPFREEIQWDVDTIYHRQG
CRHFSLGDFSHLGS----RDLALSVAALSYNLWFRCLSCVDMKLSLEVSEQILHMMSQSS
HLEELVLETCGLRG--------------DFVRRLAQALSGHS

PF13516 // ENSGT00390000014487_1_Domain_0 (343, 378)

SSGLRELSLAGNLLDDRG
M-------------AALSTHLEHCPGALRRLSLAQTGLTSR-------------------
-------GMRALGQALAANA-AFDSTLTHLDLSGNPGALGASEDSGGLYSFLS----RPN
VLTVLNLAGTDTALDT--------------------------------------------
LFTALSGGCCAKLAHLDASRNIFSRTKSRAV-----PAALQLFLSSTETLRHLGLA---G
CKLPPEALRALLDGLALNTHIRNLHLDLSACELHSAGAQVIQDLVCDAGSLSSLDLTDNG
FGSDMVTLVLAIGRSRSLKHVALGRNFNVRCKETLDDVLHRIVQLIQDDDCPLQSLSVAE
SRLKLSASILLQALG

PF13516 // ENSGT00390000014487_1_Domain_3 (736, 760)

TNP-KLTTLDISGNALGDAGAKML

ENSGT00390000014487_1_Linker_3_4 (760, 977)

AKALRVNTRLRSV---IWDRN
HTSALGLLDVA---QALEQN-HSLKSMPLPLNDVTQAQRSRPELTARAVHQIQACLLRNN
RADTSASESASCLKPLDLISDRSEQEVNELCQSVQEHMELLGCEAGPQAEAVVHQA----
-EDAIQNANFSLSILPTLY----EAGNSPSHHWQLQQKLGGLLGQVGEVCRQDIQ-----
-------DFTHATLDT

PF16000 // ENSGT00390000014487_1_Domain_4 (977, 1416)

TRSLCPKMLQGPGCREQLEGVLAGSRSL-----PDLLPEQLLQD
TFTRLRNMRLSVT--GTLADSIMAQALAGLNAARDRLVES----------LAQQAPVTTP
PAVSAL-GGGEPSPLGPGEL------EGL--FFPVENEEE--------KEEKDARSTQKW
PEP------------SHCPHLVTSPHGAAE-----------------------EAEPEPE
LAAPGEDAE---------------PQAGPSARGSPSPAAP---GPPAVPLPRMDL----P
PAGQ-P--------LRHPTR-ARPRPR-RQHHH---------------------------
------RPP---PGGPQVAPALLQE----GNGLSARVDEGVEEFFSKRLIQQDRLWAP--
DEDPATEEGGATPVPRTLRKKLGTLFAFKKPRSTRSPRPDLETSPG-AAARARKATLGDL
LRPPARPGRGEEP------------GGAEG-GISSPDPTRRSRPRYTRESKAYSMILLPA
EEE---ATLGARPDKRRP---LERGDTELAPSFEQRVQVMLQRIGVSRGSAGAEGKRKQS
KDGEIKKAGSDGDIMDSSTETPPISIKSRTHSVSADPSRRPGP---GGQGPESATWKTLG
QQLNAELRGRGWGQQDGPGPP-------SP---CPS------PSPRRPSPSPDILNLPED
PCLGPRNEDGQL-RPRPLSAGRRAVSVHEDQLQAPAERP----L----RLQRSPVLKRRP
KLEAPS-SPS-LGSSLGTNISPTQPIEPS--S-P------ERSLPSPATDQ-----RGGG
PN---L-----------

------------------------------------------MAQ-TPDGISCELRGEIT
RFLWPKEVELLLKTWLPG-EDA---VQNHVLALLRWRAYLLHTTCLPLRVDCTFSYLEVQ
AMALQETPPQVTFEL-ESLRELVLEFPGVAALEQLAQHVAAAIKKVFPRSTLGKLFRRPT
PASMLARLE-RSSPLEST--GPCSPCGGFLETYEALCDYNGFPFREEIQWDVDTIYHRQG
CRHFSLGDFSHLGS----RDLALSVAALSYNLWFRCLSCVDMKLSLEVSEQILHMMSQSS
HLEELVLETCSLRG--------------DFVRRLAQALAGHS

PF13516 // ENSGT00390000014487_1_Domain_0 (343, 378)

SSGLRELSLAGNLLDDRG
M-------------AALSRHLERCPGALRRLSLAQTGLTPR-------------------
-------GMRALGRALATNA-AFDSALTHLDLSGNPGALGSSEDSGGLYSFLS----RPN
VLSFLNLAGTDTALDTVRGCSAGGWRID------RADWRAGQGGL-G-PPAGAANSLLPQ
LFAALSRGCCTSLTHLDASRNVFSRTKSRAA-----PAALQLFLSRARTLRHLGLA---G
CKLPPDALRALLDGLALNTHLRDLHLDLSTCELRSAGAQVIQDLVCDAGAVSSLDLADNG
FGSDMVTLVLAIGRSRSLRHVALGRNFNVRCKETLDDVLHRIVQLMQDDDCPLQSLSVAE
SRLKLGASVLLRALA

PF13516 // ENSGT00390000014487_1_Domain_3 (736, 760)

TNP-NLTALDISGNAMGDAGAKLLAKALRVNSRLRSV---VWDRN
HTSALGLLDV---AQALEQN-HSLKAMPLPLNDVAQAQRSRPELTARAVHQIQACLLRNN
RADPASSDHTTCLQPLGLVSDPSEQEVNELCQSVQEHVELLGCGAGPQGEAAVRQA----
-EDAIQNANFSLSILPILY----EAGSSPSHHWQLGQKLEGLLGQVGEVCRQDVQ-----
-------DFTQATLDTARSLCPQMLQGSSWREQLEGVLAGSRGL-----PELLPEQLLQD
AFTRLRDMRLSIT--GTLADSIVAQALAGLSAARDRLVES----------LAHQATVTMP
PALPAP-DGAEPSLLEPGEL------EGL--FFPEEEKE-E-------EEEKDDSPPQKW
PEL------------SHGLHLVPFIQ----------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------V

PF16000 // ENSGT00390000014487_1_Domain_4 (1339, 1415)

PPALPQE----GNGLSARVDEGVEEFFSKRLIQQDRLWAP--
EEDPAT-EGGATPVPRTLRKKLGTLFAFKKPRSTRGPRPDLETSPG-AAPRTRKTTFGDL
LRPPTHPSRGEEP------------GGAEG-DTSSPDPARRSRPRYTRDSKAYSMILLPA
EEE---ATLGARPDKRRP---LERGETELAPSFEQRVQVMLQRIGVSRGSGGAEGKRKQS
KDGEIKKAGSDGDIMDSSTEAPPISIKSRTHSVSADPSCRPCP---GSQGPESATWKTLG
QQLNAELRSRGWGQQDGPGPP-------SP---GQS------PSPCRTSPSRDSLGLPED
PCLGPRNEDGQL-RPRPLSAGRRAVSVHEDQLQAPAERP----L----RLQRSPVLKRRP
KLEAPP-SPS-LGSGLGTEHLPPQPTEPS--S-P------EQSPPSPATDQ-----RGGG
PS---P-----------

------------------------------------------MA-QTPDGISCELRGEIT
RFLWPKEVELLLKTWLPG-EGA---VQNHVLALLRWRAYLLHTTCLPLRVDCTFSYLEVQ
AMALQETPPQVTFEL-ESLRELVLEFPGVAALEQLAQHVAAAIKKVFPRSTLGKLFRRPT
PAPMLARLE-RSSPLEST--GPCSPCGGFLETYEALCDYNGFPFREEIQWDVDTIYHRQG
CRHFSLGDFSHLGS----RDLALSVAALSYNLWFRCLSCVDMKLSLEVSEQILHMMSQSS
HLEELVLETCGLRG--------------DFVRRLAQALAGHS

PF13516 // ENSGT00390000014487_1_Domain_0 (343, 378)

SSGLRELSLAGNLLDDRG
M-------------AALSRHLERCPGALRRLSLAQTGLTPR-------------------
-------GMRALGRALATNA-AFDSALTHLDLSGNPGALGSSEDSGGLYSFLS----RPN
VLSFLNLAGTDTALDTVRGCSVGGWMID------RADWRAGQGGL-G-PPAGAANSLPPQ
LFAALSRGCCTSLTHLDASRNIFSRTKSRTA-----PAALQLFLSRARTLRHLGLA---G
CKLPPDALRALLDGLALNTHLRDLHLDLSTCELRSAGAQVIQDLVCDAGAVSSLDLADNG
FGSDMVTLVLAIGRSRSLRHVALGRNFNVRCKETLDDVLHRIVQLMQDDDCPLQSLSVAE
SRLKLGASVLLRALA

PF13516 // ENSGT00390000014487_1_Domain_3 (736, 760)

TNP-NLTALDISGNAMGDAGAKLL

ENSGT00390000014487_1_Linker_3_5 (760, 977)

AKALRVNSRLRWAGSEGWDQR
AGG-AGLNEAEQMESVVWDR-NHTSAMPLPLNDVAQAQRSRPELTARAVHQIQACLLRNN
RADPASSEHTTCLQLLGLVSDPSEQEVNELCQSVQEHVELLGCGSGPQGEAAVRQA----
-EDAIQNANFSLSILPILY----EAGSSPSHHWQLGQKLEGLLGQVGEVCRQDIQ-----
-------DFTQATLDT

PF16000 // ENSGT00390000014487_1_Domain_5 (977, 1028)

ARSLCPQMLQGSSWREQLEGVLADSRGL-----PELLPEQLLQD
AFTRLRR

ENSGT00390000014487_1_Linker_5_4 (1028, 1195)

LEWGLE--HCGIRG----LWAGLRGDVHTLAFGKPQHAVTWPSSLQG------
-SRRWP-GGGGR---------------------------G--------ERGVAGPLPAPW
RSPAAPGLRRTSRARRSVLLLVLSPQVLAE-----------------------E

PF16000 // ENSGT00390000014487_1_Domain_4 (1195, 1415)

SEPEPE
LAAPGEDAE---------------PQGWPLP--------P---PAPGRTLPRMDL----P
CASD-P--------AGR-----GRAAT-AQHHH---------------------------
------RPP---PGGPQVPPALPQE----GNGLSARVDEGVEEFFSKRLIQQDRLWAP--
EEDPAT-EGGATPVPRTLRKKLGTLFAFKKPRSTRGPRPDLETSPG-AAPRTRKTTFGDL
LRPPTRPSRGEEP------------GGAEG-DTSSPDPARRSRPRYTRDSKAYSMILLPA
EEE---ATLGARPDKRRP---LERGETELAPSFEQRVQVMLQRIGVSRGSGGAEGKRKQV
KGR----WHAVGDIMDSSTEAPPISIKSRTHSVSADPSCRPCP---GSQGPESATWKTLG
QQLNAELRSRGWGQQDGPGPP-------SP---GQS------PSPCRTSPSRDSLGLPED
PCLGPRNEDGQL-RPRPLSAGRRAVSVHEDQLQAPAERP----L----RLQRSPVLKRRP
KLEAPP-SPS-LGSGLGTEHLPPQPTEPS--G-P------EQSPPSPATDQ-----RGGG
PS---P-----------

------------------------------------------MA-KTPDGISCELRGEIT
RFLWPKEVELLLKTWLPQ-EGA---ERSYVLALLRWRAYLLH-TCLPLRVDCTFSYLEVQ
AMALQETPPQVTFEL-ESLPELVLEFPGVATLEQLAQHVASAIKKVFPHSALGKLFRKPT
PDSMLARLE-RSSPSEFT--APSSPCGKGQS---KLCYFLP-------IQDVDTIYHRQG
CRQFNLGDFSHLGS----RDLALSVAALSYNLWFRRLSCVDMKLSLEVSEQILHMMGQSS
YLEELVLETCGLKGAGPVNLISGVLVLRDFVRRLAQALARHSH

PF13516 // ENSGT00390000014487_1_Domain_1 (344, 432)

SGLRELSLAGNLLDDRG
M-----------------------------------------------------------
---------RALGRALAINT-AFDSVLTHLDLSGNPGALGASEDNGGLYSFLS----RPN
FLMFLNLAGTDAALDT--------------------------------------------
LFAALSRGCCASLTHLDTSRNVFSRCKSQAA-----PVPLQLFLSRAETLRHLCLA---G
CKLPPEALRAVLDGLALNTHIRDLHLDLSACELRSAGAQVIQDLVCDAGVVSSLDLADNG
FGSDMVTLVLAIGRSQSLRHVALGRNFNVRCKETLDDVLHRIVQLMQDDDCPLQSLSVAD
SRLKLGASVLLRALG

PF13516 // ENSGT00390000014487_1_Domain_3 (736, 760)

TNP-NLTALDISGNAMGDAGAKML

ENSGT00390000014487_1_Linker_3_4 (760, 978)

AKALRVNTRLRSV---IWDRN
HTSALGLLDVA---QALEQN-HSLKAMPLPLNDVAQAQRSRPELTARAVHQIQTCLLRNN
REDPASSGGTSCLQPLNLVSEHSEQEVNKLCQSVQEHMELLGCGAGPQGEAAVHQA----
-EDAIQNANFFLSILPILN----EAGNSPSHHWQLRQKLEALLGQVGEVCHQDIQ-----
-------DFIQAILDT-

PF16000 // ENSGT00390000014487_1_Domain_4 (978, 1415)

RSLYPQMLQGPGWREQLEGILVGSKGL-----PELLPEQLLHD
AFIGLRDMRLSERQCRTLAESIVAQALAGLNAARDRLVES----------LAQQAPVAVA
PALPAL-DGGEPSPLGPETL------EGF--FFPEDKEE-----------EKTESPLRKW
PEH------------NQCLHLLPCDHSVAE-----------------------EAELEPE
LAAPGEDAE---------------PQAGPSARGSPSPAAP---GPSTGPLPRMDL----P
PAGQ-P--------LRHPTR-ARPRPR-RQHHH---------------------------
------RPP---PGGPQVPPALPQE----GNGLSARVDEGVEEFFSKRLIQQDRLWAP--
E-EEPVTEGGATPVPRTLRKKLGTLFAFKKPRSTRGPRPDLETSLG-AAARTRKTTLGDL
LRPPARSSRVEEP------------GGAEG-GPSSPDPARRSRPRYTRESKAYSMILLPA
EEE---ETLNARPDKRRP---LERGDTELAPSFEQRVQVMLQRIGVSRGSGGAEGKRKQS
KDGEIKKAGSDGDIMDSSTETPPISIKSRTHSVSADPSCRPGP---GVQEPESATWKTLG
QQLNAELRGRGWGQQDGPGPP-------SP---CPS------PNLRRATPAPDILGLPED
PCLGPRNEDGQL-RPRPFSAGRRAVSVHEDQLQAPAERP----L----RLQRSPVLKRRP
KLEAPP-SPS-LGSGLGTEPLPPRPTEPT--S-P------EQSPPSPATDQ-----RGGG
PN---P-----------

------------------------------------------MA-QTPDSISCELRGEIT
RFLWPKEAELLLKTWLPQ-EGS---ERSHILALLRWRAYLLH-TCLPLRVDCTFSYLEVQ
AMALQETPPQVTFEL-ESLPELVLEFPGVATVEQLAQHVASAIKKVFPRSTLGKLFRKPT
PTSMLARLE-RSNPSESM--APRSPCGGFLETYEALCDYNGFPFREEIQWEVDTIYHRQG
CRQFSLGDFSHLGS----RDLALSVAALSYNLWFRCLSCVDMKLSLEVSEQILHMMGQSS
HLEELVLETCGLRG--------------DFVRRLAQALAGHS

PF13516 // ENSGT00390000014487_1_Domain_0 (343, 378)

SSGLRELSLAGNLVDDRG
M-------------AALSRHLEHRPGALRRLNLAQTGLTPR-------------------
-------GMRALGQALATNA-AFDSALTHLDLSCNPGALGASEDNGGLYSFLS----RPN
ALMFLNLAGTDAALDT--------------------------------------------
LFTALSSGCCSSLTYLDTSRNVFSRCKSPAA-----AASLQLFLSRAETLRHLGLA---G
CKLPPEALRAVLDGLALNTHIRDLHLDLSACELRSAGAQVIQDLVCDAGVVSSLDLEDNG
FGSDMVTLVLAIGRSQSLRHVALGRNFNVRCKETLDDVLHRIVQLMQDDDCPLQSLSVAD
SRLKLGAGVLLRALS

PF13516 // ENSGT00390000014487_1_Domain_3 (736, 760)

TNP-NLTALDISGNAMGDTGAKML

ENSGT00390000014487_1_Linker_3_4 (760, 977)

AKALGVNTRLRSV---IWDRN
HTSALGLLDVA---QALEQN-HSLKDMPLPLNDVVQAQRSRPELTARAVHQIQACLLRNN
HEDPTSSGPSSCLQPLNLVSDHSEQEVNELCQSVQEHMELLGCGAGPQGEAAVHQA----
-EDAIQNANFFLSILPILN----EAGNSPSYQWQLRQKVEALLEQVGEVCRQDIQ-----
-------DFIQAILDT

PF16000 // ENSGT00390000014487_1_Domain_4 (977, 1116)

TRSLCRQMLQGPGWREQLEGVLVGSEGL-----PELLPEQLLQD
VFTRLRDIRLSVT--GTLSENIVAQALAGLSAAQDRLVES----------LAQQAPVAMP
PSLPAL-DGGELSPLGPGAL------EGF--FFPEDKEEEE-------EKENDESPLWKW
PE--------------HCLHLVPFDYQ---------------------------------
------------------------------------------------------------
-----P--------LRHPTR-ARPRPR-RQHHH---------------------------
------RPP---PGGPQVPPALPQE----GNGLSARVDEGVEEFFSKRLIQQDCLWAP--
E-EDPATEGGATPVPRTLRKKLGTLFAFKKPRSTRGPRPDLETSPG-AAARTRKTTLGDL
LRPPARPGRGEEP------------GGTEG-GPSSPDPARRSRPRYTRESKAYSMILLPA
E-E---ETLNARPDKRRP---LERGDTELTPSFEQRVQVMLQRIGVSRGSGGAEGKRKQS
KDGEIKKAGSDGDIMDSSTETPPISIKSRTHSVSADPSCRPGP---GVQGPESATWKTLG
QQLNAELRGRGWGQQDGPGPP------SSP---CPS------PNFRRASPAPDSLGLPED
PCLGPRNEDGQL-RPRPLSAGRRAVSVHEDQLQGPAERP----L----RLQRSPVLKRRP
KLEAPP-SPS-LGSGLGTEPLPPQPTEPS--S-P------EQSPPSPATDQ-----RGGG
PN---L-----------

------------------------------------------MAQ-TPDGISCELRGEIT
RFLWPKEAELLLKTWLPQ-ESG---ERSHILALLRWRAYLLH-TCLPLRVDCTFSYLEVQ
AMALQETPPQATFEL-ESLPELVLEFPGVAALEQMAKHVAAAIKKVFPRSTLGKLFRKPT
PTSILARLE-RSSSAEST--APGSPCGGFLETYEALCDYNGFPFQEEIQWDVDTIYHRQG
CRHFNLGDFSHLGS----RDLALSVAALSYNLWFRCLSCVDMKLSLEVSEQILHMMSQSS
HLEELVLETCGLRG--------------DFVRRLAQALAGQS

PF13516 // ENSGT00390000014487_1_Domain_0 (343, 378)

SSGLRELSLAGNLLDDRG
M-------------AALSRHLEHRPGALKKLSLAQTGLTQR-------------------
-------GMRALGRALAINA-DFDSALTHLDLSGNPGALGASEDNGGLYSFLR----RPN
VLMFLNLAGTDAALDT--------------------------------------------
LFAALSRGCCSNLSYLDASRNVFSRTKSRAA-----PAALQLFLSRAGTLRHLGLA---G
CKLPPDALRALLDGLALNTHIHDLHLDLSACELRSAGAQVIQDLVCDASAVSSLDLADNG
FGSDMVTLVLAIGRSRSLRHVALGRNFNVRCKETLDDVLHRIVQLMQDDDCPLQSLSVAE
SRLKLGASVLLRALG

PF13516 // ENSGT00390000014487_1_Domain_3 (736, 760)

TNP-NLTSLDISGNAMGDTGAKML

ENSGT00390000014487_1_Linker_3_4 (760, 977)

AKALRINTRLRSV---IWDRN
QTSALGLLDVA---QALEQN-HSLKNMPLPLNDVAQAQRSRPELTARAVHQIQTCLLRNN
RANPVSSDRASCLQPLGLVSDRSEQEVNELCQSVQEHMELLGCGAGPQGEAAVHQA----
-EDAIQNANFSLSILPILD----EAGNSPSHHWQLQQKLESLLGQVGKLCHQDIQ-----
-------DFTQATLDT

PF16000 // ENSGT00390000014487_1_Domain_4 (977, 1415)

TRSLCPQMLQGPGWREQLEGVLVGSKGL-----PELLPEQLLQD
IFTRLRDMRLSVT--RTLAESIVTQALAGLSAARDRLVEN----------LAEQAPVAMP
PALPAL-DGGESCSLRPGEL------ECL--FFPEEEKEVE---E--EEEKKDDCPSRKW
LEP------------SHCFHLVPSGAAEEA-----------------------EREPEPE
LAAPGEDAE---------------PQAGPSARGSPSPAAP---GPPAGPLPRMDL----P
PAGQ-P--------LRHPTR-ARPRPR-RQHHH---------------------------
------RPP---PGGPQVPPALPQE----GNGLSARVDEGVEEFFSKRLIQQDRLWAP--
EEDLAT-EGGPTPVPRTLRKKLGTLFAFKKPRSTRGPRPDLETSPG-AAARTRKATLGDL
LRTPARPGRGEDP------------GGVEG-GTSSPDTARRSRPRYTRESKAYSMILLPA
EEE--EATLGARPDKRRP---LERGDTELAPSFEQRVQVMLQRIGVSRGSGGAEGKRKQS
KDGEIKKAGSDGDIMDSSTETPPISMKSRTHSVSADPSCRPGP---GGQGPESATWKTLG
QQLNAELRGRGWGQQDGPGPP-------SP---CPS------PRPCRASPSPDSLGLPED
SCLGPRNEDGQL-RPRPLSAGRRAVSVHEDQLQAPAERP----L----RLQRSPVLKRRP
KLEAPP-SPS-LGSGLGTEPLLPQPTEPS--S-P------ERSPPSPATDQ-----RGGG
PN---P-----------

------------------------------------------MAQTPDGGISCELRGEIT
RFLWPKEAELLLQTWLPEREGA---ERGHVLALLRWRAYLLH-TCLPLRVDCTFSYLEVQ
AMALQETPPQVTFEL-ESLPELVLEFPGVAALEQLAQHIAAAIKKVFPCSTLGKLFRRPT
SPSMLARLE-RSSPSEDT--VPSSPCGGFLETYEALCDYNGFPFREEIQWDVDTIYHRQG
CRHFSLCDFSHLGS----RDLALSVAALSYNLWFQCLSCVDMKLSLEVSEQILHMMSQSS
HLEELVLENCGLRG--------------DFVRRLAQALAGHSSSALRELSLNGNLLDDRG
TRGLGTPGGWCWSVTALSRHLEHRPGALRRLGLAHTGLTPR-------------------
-------GRSGPGGG------------------------------GGVI-----------
------------------------------------------------------------
-------------VHA--------------------------------------------
-------------------------------------------VPTPSPPPQPLLMRDPS
FGSDMVTLVLDIGRSRSLRHVALGRNFNVRCKETLDDVLHRIVQLMQDDDCPLQSLSVAE
SRLKQASSVLLRALGT

PF13516 // ENSGT00390000014487_1_Domain_3 (737, 761)

NP-NLTALDISGNAMGDTGAKMLAKALRVNTRLRSV---VWDRN
HTSALGLLDVA---QALEQN-RSLKAMPLPLNDVAQAHRSRPELTARAVHQIQACLLRNN
RADHASSDRMPRPRPPGLVSDPSEQEVNELCQSVQEHMELLGCGAGPQGEAAVHQA----
-EDAIQNANFSLSILPILY----EAGSSPSHQWQLRQKLEGLLGQVGEVCRKDIQ-----
-------DFTQATLDTTRSLCPQMLQGPRWREQLEGVLVGSRGL-----PELLPEHLLQD
AFTRLRDMRLSVT--GTLAESIVAQALEGLNAARDRLVEN----------LARQATVAMP
LAIPAL-DGGETSPLGPGEL------EGL--FFPEEVKEKQEDEEEQKVLLRNRSPSWRL
RGK------------MRSRRR---------------------------------------
---------------------------GLL-----------------RVVPERCW----A
---------------------PRLRGK-SCIYC---------------------------
------RSS---GCLYEVPPALPQE----GNGLSARVDEGVEEFFSKRLIQQDRLWVP--
EEDPAN-EGGATPVPRTLRKKLGTLFAFKKPRSTRGPRPDLETSPG-AAPRTRKTTLGDL
LRPPARPGRGEEP------------GGAEG-GTSSPDPARRSRPRYTRESKAYSMILLPA
EEE--EETLGARPDKRRP---LERGDTELAPSFEQRVQVMLQRIGVSRSSGSAEGKRKQS
KDGEIKKAGSDGDIMDSSTEAPPISIKSRTHSVSADPSCRPGP---GGQGPESTSWKTLG
QQLNAELRGRGWGQQDGPGPP-------SP---CPS------PSPRRASPSPDSLGLPED
PCLGPRNE----------------------------ERP----L----RLQRSPVLKRRP
KLEAPS-SPS-LGSGLGTQPPPPQPTEPS--S-P------EPTPPSPATD-----QRGGG
PN---P-----------

------------------------------------------MAQTPD-SISCELRGEIT
KFLWPKEAELLLKTWLPEREGA---EQGHVLVLLRWRAYLLH-TCLPLRVDCTFSYLEVQ
AMVLQETPPQITFEL-ESLPELVLEFTGVAALEQLAQHIAAAIRKVFPRSTLGKLFRRPT
PPSMLARLE-KSSSSEAT--SPSSPCGGFSETYEALCDYNGFPFREEIQWDVDTIYHRQG
CRHFSLGDFSHLGS----RDLALSVAALSYNLWFRCLSCVDMKLSLEVSEQILHMMNQSS
HLEELVLETCGLRG--------------DFVRRLAQALAGHTS

PF13516 // ENSGT00390000014487_1_Domain_0 (344, 378)

SGLRELSLAGNLLDDRG
V-------------AALSRHLEKHPGALRRLSLAQTGLTPR-------------------
-------GMRALGRALASNS-AFDSALTHLDLSGNPGALGASEDRGGLYSFLS----RPN
VLTFLNLAGTDTALDTVSGGGDGG--------------------GALSPPASVAHTLLSQ
LFAALSRGGCSSLAHLDASRNVFSRTKSRAA-----PDALQLFLSRAGTLRHLGLA---G
CKLPPDALRALLEGLALNTHLNDLHLDLSACELRSAGAQVIQDLVCDAGAVSSLDLADNG
FGSDMVTLVLAIGRSRSLRHVALGRNFNVRCKETLDDVLHRIVQLMQDDDCPLQSLSVAE
SRLKLGAGVLLRALRVNT-RLRWAGSQGWDQQGKRLRGANGKARGVGSSLSV---VWDRN
HTSALGLLDVA---QALEQN-RSLKAMPLPLNDVAQAQRSRPELTARAVHQIQACLLRNN
RTDHTSADCTSRPKPLGLGSDPSEQEVNELCQSVQEHVELLGCGAGPQGEAAVHQA----
-EDAIQNANFSLSILPILY----EAGSSPSHQWQLRQKLEGLLGQVGEVCRRDIQ-----
-------DFTQATLDT

PF16000 // ENSGT00390000014487_1_Domain_4 (977, 1415)

TRSLCPQTLQGPRWREQLEGVLGGSRGL-----PELLPEHLLQD
AFTRLRDMRLSVT--GTLAESIVAQAVAGLSAARDRLVES----------LAQQATEAMP
PVILTL-DGDESSPLGPGEL------EGL--FFPEEKEKE--DEEEQKDE----SPPQKW
AES------------LHCLHLDSSTHSAA-------------------EELEPEP----E
LAAPGEDAEPQA---------------GPSARGSPSPAAP---GPPAGPLPRMDL----P
PSG-QP--------LRH-PTRTRPRPR-RQHHH---------------------------
------RPP---PGGPQVPPALPQE----GNGLSARVDEGVEEFFSKRLIHQDRLWAP--
EEDPAA-EGGTTPVPRTLRKKLGTLFAFKKPRSTRGSRPDLETSPG-AAPRSRKTTLGDL
LRPPARPGRGEEPA------------GAEG-GTGSPDPTRRSRPRYTRESKAYSLILLPA
EEE---ETVGARPDKRRP---LERGDTELAPSFEQRVQVMLQRIGVSRGSGSADGKRKQS
KDGEIKKAGSDGDIMDSSTEAPPISIKSRTHSVSADPSCRPGP---GGQGPESATWKTLG
QQLNAELRSRGWGQQDGPGPP-------SP---CPS------PSPRRSSPSPDSLGLPED
PCLGPRNEDGRL-RPQPRLAGRRAVSVHEDQLQAPAERP----L----RLQRSPVLKRRP
KLEAPP-SPS-IGSGLEAEPLPTQSTEPS-------------SLPSPTTN-----QRGGG
PN---P-----------

------------------------------------------MAQ-TPDGISCELRGEIT
RFLWPKEVELLLKTWLPG-EGA---VQNHVLALLRWRAYLLHTTCLPLRVDCTFSYLEVQ
AMALQETPPQVTFEL-ESLRELVLEFPGVAALEQLAQHVAAAIKKVFPRSTLGKLFRRPT
PASMLARLE-RSSPLEST--GPCSPCGGFLETYEALCDYNGFPFREEIQWDVDTIYHRQG
CRHFSLGDFSHLGS----RDLALSVAALSYNLWFRCLSCVDMKLSLEVSEQILHMMSQSS
HLEELVLETCGLRG--------------DFVRRLAQALAGHS

PF13516 // ENSGT00390000014487_1_Domain_0 (343, 378)

SSGLRELSLAGNLLDDRG
M-------------AALSRHLERCPGALRRLSLAQTGLTPR-------------------
-------GMRALGRALATNA-AFDSALTHLDLSGNPGALGSSEDSGGLYSFLS----RPN
VLSFLNLAGTDTALDTVRGCSVGGWMTD------RADWRAGQGGL-G-PPAGAANSLPPQ
LFAALSRGCCTSLTHLDASRNVFSRTKSRAA-----PAALQLFLSRARTLRHLGLA---G
CKLPPDALRALLDGLALNTHLRDLHLDLSACELRSAGAQVIQDLVCDAGAVSSLDLADNG
FGSDMVTLVLAIGRSRSLRHVALGRNFNVRCKETLDDVLHRIVQLMQDDDCPLQSLSVAE
SRLKLGASVLLRALA

PF13516 // ENSGT00390000014487_1_Domain_3 (736, 760)

TNP-NLTALDISGNAMGDAGAKLLAKALRVNSRLRSV---VWDRN
HTSALGLLDV---AQALEQN-HSLKAMPLPLNDVAQAQRSRPELTARAVHQIQACLLRNN
RADPASSDHTTCLQPLGLVSDPSEQEVNELCQSVQEHVELLGCGAGPQGEAAVHQA----
-EDAIQNANFSLSILPILY----EAGSSPSHHWQLGQKLEGLLGQVGEVCRQDIQ-----
-------DFTQATLDTARSLCPQMLQGSSWREQLEGVLAGSRGL-----PELLPEQLLQD
AFTRLRDMRLSIT--GTLAESIVAQALAGLSAARDQLVES----------LAHQATVIMP
SALPAP-EGGEPGLLEPGEL------GGL--FFPEEEKE-E-------EEEEDDSPPQKW
PEL------------SHGLHLVPFIQR---------------------------------
------------------------------------------------------------
--------------------

PF16000 // ENSGT00390000014487_1_Domain_4 (1281, 1415)

-ARPRPR-RQHHH---------------------------
------RPP---PGGPQVPPALPQE----GNGLSARVDEGVEEFFSKRLIQQDRLWAP--
EEDPAT-EGGATPVPRTLRKKLGTLFAFKKPRSTRGPRPDLETSPG-AAPRTRKTTFGDL
LRPPTRPSRGEEP------------GGAEG-DTSSPDPARRSRPRYTRDSKAYSMILLPA
EEE---ATLGARPDKRRP---LERGETELAPSFEQRVQVMLQRIGVSRGSGGAEGKRKQS
KDGEIKKAGSDGDIMDSSTEAPPISIKSRTHSVSADPSCRPCP---GSQGPESATWKTLG
QQLNAELRSRGWGQQDGPGPP-------SP---VQS------PSPCRTSPSRDSLGLPED
PCLGPRNEDGQL-RPRPLSAGRQAVSVHEDQLQAPAERP----L----RLQRSPVLKRRP
KLEAPP-SPS-LGSGLGTEHLPPQPTEPS--S-P------ERSPPSPATDQ-----RGGG
PS---P-----------

------------------------------------------MA-QTPDGISCELRGEIT
RFLWPKEVELLLKTWLPG-EGA---VQNHVLALLRWRAYLLHTTCLPLRVDCTFSYLEVQ
AMALQETPPQVTFEL-ESLRELVLEFPGVAALEQLAQHVAAAIKKVFPRSTLGKLFRRPT
PASMLARLE-RSSPLEST--GPCSPCGGFLETYEALCDYNGFPFREEIQWDVDTIYHRQG
CRHFSLGDFSHLGS----RDLALSVAALSYNLWFRCLSCVDMKLSLEVSEQILHMMSQSS
HLEELVLETCGLRG--------------DFVRRLAQALAGHS

PF13516 // ENSGT00390000014487_1_Domain_0 (343, 378)

SSGLRELSLAGNLLDDRG
M-------------AALSRHLERCPGALRRLSLAQTGLTPR-------------------
-------GMRALGRALATNA-AFDSALTHLDLSGNSGALGSSEDSGGLYSFLS----RPN
VLSFLNLAGTDTALDTVRGCSVGGWMTD------RADWRAGQGGL-G-PPAGAANSLPPQ
LFAALSRGCCTSLTHLDASRNVFSRTKSRAA-----PAALQLFLSRARMLRHLGLA---G
CKLPPDALRALLDGLALNTHLRDLHLDLSACELRSAGAQVIQDLVCDAGAVSSLDLADNG
FGSDMVTLVLAIGRSRSLRHVALGRNFNVRCKETLDDVLHRIVQLMQDDDCPLQSLSVAE
SRLKLGASVLLRALA

PF13516 // ENSGT00390000014487_1_Domain_3 (736, 760)

TNP-NLTALDISGNAMGDAGAKLL

ENSGT00390000014487_1_Linker_3_4 (760, 977)

AKALRVNSRLRWAGSEGWDQR
AGG-AGLNEAEQMESVVWDR-NHTSAMPLPLNDVAQAQRSRPELTARAVHQIQACLLRNN
RADPASSDHTTCLQPLGLVSDPSEQEVNELCQSVQEHVELLGCGAGPQGEAAVRQA----
-EDAIQNANFSLSILPILY----EAGSSPSHHWQLGQKLEGLLGQVGEVCRQDIQ-----
-------DFTQATLDT

PF16000 // ENSGT00390000014487_1_Domain_4 (977, 1415)

ARSLCPQMLQGSSWREQLEGVLAGSRGL-----PELLPEQLLQD
AFTRLRDMRLSIT--GTLAESIVAQALAGLSAARDQLVSDLAI-------SLAGALPAI-
----FG-YGGEPGLLEPGEL------GGL--FFPEEEKEE--------EEEKDDSPPQKW
PEL------------SHGLHLVPFIQSAAE-----------------------EAEPEPE
LAAPGEDAE---------------PQAGPSARGSPSPAAP---GPPAAPLPRMDL----P
PAGQ-P--------LRHPTR-ARPRPR-RQHHH---------------------------
------RPP---PGGPQVPPALPQE----GNGLSARVDEGVEEFFSKRLIQQDRLWAP--
EEDPAT-EGGATPVPRTLRKKLGTLFAFKKPRSTRGPRPDLETSPG-AAPRTRKTTFGDL
LRPPTRPSRGEEP------------GGAEG-DTSSPDPARRSRPRYTRDSKAYSMILLPA
EEE---ATLGARPDKRRP---LERGETELAPSFEQRVQVMLQRIGVSRGSGGAEGKRKQV
KGR----WHAVGDIMDSSTEAFFFSIKSRTHSVSADPSCRPCP---GSQGPESATWKTLG
HFFFAELRSRGWGQQDVFFSP-------SP---GQS------PSPCRTSPSRDSLGLPED
PCLGFFFEDGHL-RPSFFLAGRRAVSVHEDQLQAPAERF----F----FLQRSPVLKRRP
KLFFFP-SPS-LGSGLGMEHLFFFPTEPS--S-P------ERSPPSPATDQ-----RGGG
PS---P-----------

------------------------------------------MA-KTPDGISCELRGEIT
RFLWPKE-----------------------------------------------------
----------VTFEL-ESLPELVLEFPGVATLEQLAQHVASAIKKVFPHSALGKLFRKPT
PDSMLARLE-RSSPSEFT--APSSPCGGFLETYEALCDYNGFPFREEIQWDVDTIYHRQG
CRQFNLGDFSHLGS----RDLALSVAALSYNLWFRRLSCVDMKLSLEVSEQILHMMGQSS
YLEELVLETCGLKG--------------DFVRRLAQALARHSH

PF13516 // ENSGT00390000014487_1_Domain_0 (344, 378)

SGLRELSLAGNLLDDRG
M-------------AALSRHLERRPGALRRLSLAQTGLTPR-------------------
-------GMRALGRALAINT-AFDSVLTHLDLSGNPGALGASEDNGGLYSFLS----RPN
FLMFLNLAGTDAALDTVRGVHWGTI----------GQALVGVGGL-G-APSPVANSLLLQ
LFAALSRGCCASLTHLDTSRNVFSRCKSQAA-----PVPLQLFLSRAETLRHLCLA---G
CKLPPEALRAVLDGLALNTHIRDLHLDLSACELRSAGAQVIQDLVCDAGVVSSLDLADNG
FGSDMVTLVLAIGRSQSLRHVALGRNFNVRCKETLDDVLHRIVQLMQDDDCPLQSLSVAD
SRLKLGASVLLRALG

PF13516 // ENSGT00390000014487_1_Domain_3 (736, 760)

TNP-NLTALDISGNAMGDAGAKMLAKALRVNTRLRSV---IWDRN
HTSALGLLDVA---QALEQN-HSLKAMPLPLNDVAQAQRSRPELTARAVHQIQTCLLRNN
REDPASSGGTSCLQPLNLVSEHSEQEVNKLCQSVQEHMELLGCGAGPQGEAAVHQA----
-EDAIQNANFFLSVK---------------------------------------------
------------------------------------------------------------
------------RKCRSLAESIVAQALAGLNAARDRSVMSSG------------------
-----V-MQPRPSPLGPETL------EGF--FFPEDKEEEKVSDPR-----------ILG
----------------PGLKIFPS---CPG-----------------------VWKV---
------------------------------------------RGNSSGV-----------
------------------------------------------------------------
-----------MPPHPKL

PF16000 // ENSGT00390000014487_1_Domain_4 (1339, 1415)

RLSLPQE----GNGLSARVDEGVEEFFSKRLIQQDRLWAP--
EEEPVT-EGGATPVPRTLRKKLGTLFAFKKPRSTRGPRPDLETSLG-AAARTRKTTLGDL
LRPPARSSRVEEP------------GGAEG-GPSSPDPARRSRPRYTRESKAYSMILLPA
EEE---ETLNARPDKRRP---LERGDTELAPSFEQRVQVMLQRIGVSRGSGGAEGKRKQV
SLGVKFIL--HTDLIVSST-PFPLYIVSADTLLPADPSCRPGP---GVQEPESATWKTLG
QQLNAELRGRGWGQQDGPGPP-------SP---CPS------PNLRRATPAPDILGLPED
PCLGPRNEDGQL-RPRPFSAGRRAVSVHEDQLQAPAERP----L----RLQRSPVLKRRP
KLEAPP-SPS-LGSGLGTEPLPPRPTEPT--S-P------EQSPPSPATDQ-----RGGG
PN---P-----------

------------------------------------------MA-QTPDGISCELRGEIT
RFLWPKEVELLLKTWLPG-EGA---VQNHVLALLRWRAYLLHTTCLPLRVDCTFSYLEVQ
AMALQETPPQVTFEL-ESLRELVLEFPGVAALEQLAQHVAVAIKKVFPCSTLGKLFRRPT
PASMLARLE-RSSPSEST--DPCSPCGGFLETYEALCDYNGFPFREEIQWDVDTIYHRQG
CRHFSLGDFSHLSS----RDLALSVAALSYNLWFRCLSCVDMKLSLEVSEQILHMMSQSS
HLEELVLETCGLRG--------------DFVRRLAQVLAGHSSSGLRELSLAGNLLDDRG
M-------------AEGRGWEEVRPTSPEETQPHPDR---------------VDTERVGG
LPSARLLRMRALGQALATNA-AFDSILTHLDLSGNPGALGPSEDSGGLYTFLS----RPN
VLSFLNLAGTDTALDIVRGCSVGGWMIC------REDWRVGRDGE--------ANTLPPQ
LFAALSRGCCSSLTHLDASRNVFSRTKSRAA-----PATLQLFLSRAGTLRHLGLA---G
CKLPPDALRALLDGLALNTHLRDLHLDLSACELRSAGAQVIQDLVCDAGAVSSLDLADNG
FGSDMVTLVLAIGRSRSLRHVALGRNFNVRCKETLDDVLHRIVQLMQDDDCPLQSLSVAE
SRLKLGASVLLRALA

PF13516 // ENSGT00390000014487_1_Domain_3 (736, 760)

TNP-NLTALDISGNAVGDTGAKLL

ENSGT00390000014487_1_Linker_3_4 (760, 977)

AKALRVNSRLRWAGSEGWDQR
AGGLVEEAKERGRGSVVWDR-NHTSAMPLPLNDVAQAQRSRPELTARAVHQIQACLVRNN
RADPASSDHTTHLQPLSLVSDPSEQEVNELCQSVQEHVELLGCGAGPQGEAAVRQA----
-EDAIQNANFSLSILPILY----EAGSSPSYYWQLGQKLGGLLGHVGEVCRQDIQVSWFD
PYPIVLTDFTQATLDT

PF16000 // ENSGT00390000014487_1_Domain_4 (977, 1236)

ARNLCPQMLQGSSWREQLEGVLAGSSGL-----PELLPEQLLQD
AFTRLRDMRLSIT--GTLAESIVAQALAGLSAARDRLVAS----------LAQQATVTMP
PSLPAL-NGGQPSPLEPGEL------EGL--FFSKEEKEEEEKEKVKSSSSGDDGPARKW
PEL------------SHSLHLVPFIHSAAE-----------------------EAEPEPE
LAAPGEDAE---------------PQAGPSARGSPR------------------------
-----------------------------PHHH---------------------------
------RPP---PGGPQVPPALPQE----GNGLSARVDEGVEEFFSKRLIQQDRLWAP--
EEDPAT-EGGTTPVPRTLRKKLGTLFAFKKPRSTRGPRPDIETSPG-AAPRTRKTTFSDL
LRPPTRPSRGEEL------------GGAEG-DTSSPDPARRSRPRYTRDSKAYSMILLPA
EEE---AMLGARPDKRRP---LERGETELAPSFEQRVQVMLQRIGVSRGSGGAEGKRKQS
KDGEIKKAGSDGDIMDSSTEAPPISMKSRTHSVSADPSCRPGP---GSQGPESATWKTLG
QQLNAEFRSRGWGQQDGPGPP-------SP---GQS------PGPCRASPSPDSLGLPED
PCLGPRNEDGQL-RPRPLSAGRRAVSVHEDQLQAPAERP----L----RLQRSPVLKRRP
KFEAPP-SPS-LGSGLGTEPLHPQPTEPS--S-P------ERSPPSPATDQ-----RGGG
PN---P-----------

------------------------------------------MAHTPD-GISCELRGEIT
KFLWPKEAELLLKTWLPQ-EGA---EQSHILALLRWRAYLLH-TCLPLRVDCTFSYLEVQ
AMALQETPPRVTFEL-ESLPKLVLEFPGVAALEQLAQHVAAAIKKVFPRSTLGKLFRKPT
PSSLLARLE-KSHPLEST--VPSSPCGGFLETYEALCDYNGFPFREEIQWDVDTIYHRQG
CRHFCLGDFSHLGS----RDLALSVAALSYNLWFRRLSCMDMKLSLEVSEQILHMTSQSS
YLEELVLETCGLRG--------------DFVRRLAQALAGHF

PF13516 // ENSGT00390000014487_1_Domain_0 (343, 377)

NSGLRELSLSGNLLDDRG
M-------------ATLSRHLEHCPGALRKLCLAQTGLTPR-------------------
-------GMRALGRALATNA-TFDSTLTHLDLSGNPGALGASQDGGGLYTFLS----RPN
VLAYLNLAGTDTALG--------------------------------------------M
LFMALSGGCCANLTHLEASRNIFSRTKSQAV-----PDALQRFLGGARMLRHLGLA---G
CKLPPEALRALLDGLALNTQIHDLHLDLSACELRSVGAQVIQDLVCDAGALSSLDLSDNG
FGSDMVTLVLAIGRSRSLKHVALGRNFNVRCKETLDDVLHRIVQLMQDDDCPLQSLSVAE
SRLKQGASVLIRALG

PF13516 // ENSGT00390000014487_1_Domain_3 (736, 760)

TNP-KLSVLDISGNAIGDTGAKML

ENSGT00390000014487_1_Linker_3_4 (760, 977)

AKALRVNTRLRSV---IWDRN
NTSALGLLDVA---EALEQN-HSLKSMPLPLNDITQAHRSRPELTARAVHQIQACLWRNN
RADS-TSDRKPCLQPLGLISDHSEQ-VNELCQSVQEHVELLGCGAGPQGEVAVHQA----
-EDAIQNANFSLSILPILF----EAGSSPSHHWQLQQKLEGLLGQVGEICRQDIQ-----
-------DFTQTTLDT

PF16000 // ENSGT00390000014487_1_Domain_4 (977, 1415)

TRSLCPQMLQRPGWRKQLEGVLVGSGGL-----PELLPEHLLQD
ALTRLRDMRLSIT--GTLAENIVAQALAGLHAARDRLVES----------LAQQAPVTVV
PAVPPL-CGDELTLLESGGV------EEF--FFPTEEEEEREKD---------DGSSWKW
LEP------------SNCFLV-----------------------PSL-HGAAEEAERDPE
LAAPGEDAEPQA---------------GPSARGSPSPAAP---GPPAGPLPRMDL----P
PAGQ-P--------LRH-PTRARPRPR-RQHHH---------------------------
------RPP---PGGPQVSPALLQE----GNGLTARVDEGVEEFFSKRLIQQDRLWAP--
EEDTAT-EGGTTPVPRTLRKKLGTLFAFKKPRSTRGPRPDLETSPG-AAARARKTTLGDL
LRPPARPGRG-EEP-----------GGAEG-GTSSPDAARRNRPRYTRESKAYSMILLPA
EE---EAAVGARPDKRRP---LERGDTELAPSFEQRVQVVLQRIGVSRGSGGAESKRKQS
KDGEIKKAGSDGDIMDSSTETPPISIKSRTHSVSADPSCRPGP---GGQGPESATWKTLG
QQLNAELRGRGWGQQDGPGPP-------SP---CPS------PSPRRTSPAPDILSLPED
PCLGPRNE----------------------------ERP----L----RLQRSPVLKRRP
KLEAPP-PPN-LGSGLGTKPLPPYPTEPS--S-P------EQSPPSPATDQ-----RGGG
PN----P----------

------------------------------------------MAQ-TPDGISCELRGEIA
RFLWPKEAELLLKTWLPQ-EGA---ERSYVLVLLRWRVYLLH-TCLPLRVDCTFSYLEVQ
AMALQETPPQVTFEL-ESLPDLVLEVPDVAALERLAQHVAVAIKKVFPRSTLGKLFRKPT
PPSMLARLE-SGHPSEGS--APCSPCGGFLETYEALCDYNGFPFREEIQWDVDTIYHRQG
CRHFSLGDFSHLGS----RDLALSVAALSYNLWFRRLSCVDMKLSLEVSEQILHMMSQSS
HLEELLLETCGLRG--------------DFVRRLAQALAGHS

PF13516 // ENSGT00390000014487_1_Domain_0 (343, 378)

SSGLRELSLAGNLVDDRG
V-------------AALSRHLEHRPGALRRLSLAQTGLTPR-------------------
-------GMRALGRALATNV-AFDSALIHLDLSGNPGALGASEDGGGLYSFLS----RPN
VLTFLNVAGTDAALDTVRG-----------------GWGRVRGGR-G-PPAGIADTLLPQ
LFAALSRGCCTNLTHLDASRNVFSRTKSRAA-----PAALQLFLGRAGTLRHLSLA---G
CKLPPDAVRALLDGLALNTHLRDLHLDLSACELRSAGAQVIQDSVCDAGAVSSLDLADNG
FGSDMVTLVLAIGRSRSLRHVALGRNFNVRCKETLDDVLHRIVQLMQDDDCPLQSLSVAE
SRLKLSASVLLRALG

PF13516 // ENSGT00390000014487_1_Domain_3 (736, 760)

SNP-NLTALDISGNAMGDVGAKLL

ENSGT00390000014487_1_Linker_3_4 (760, 977)

AKTLRVNTRLRSV---VWDRN
NTSALGLLDVA---QALEHN-HSLKAMPLPLNDVAQAQRSRPELTARAIHQIQACLLRNN
RADPASSDRLTHLQPLSLVSNPSEQEVNELCQSVQEHMELLGCGAGPQGEAAVHQA----
-EDAIQNANFSLSILPILY----EAGSSPSHHWQLRQKLEALLRQVGEVCRQEIQ-----
-------DFTQATLDT

PF16000 // ENSGT00390000014487_1_Domain_4 (977, 1415)

TRSLCPQILQGSGWREQLEGALVGSRGF-----PELLPEQLLQN
AFTRLRDMQLSVT--GTLAESIVAQALAGLSAARDRLVES----------LAQQATVVVP
SALPTL-DGGEPSPLGPGEL------EGL--FFPEEKE------------EKEDDSPRKW
PEP------------SHVLRPASSIHSAAE-------------------------EPEPE
LAAPGEDAE---------------PQAGPSVRGSPSPAAP---GPQAGPLPRMDL----P
PAGQ-P--------LRHPTR-ARPRPR-RQHHH---------------------------
------RPP---PGGPQVPPALPQE----GNGLSARVDEGVEEFFSKRLIQQDRLWAP--
EEDPAT-EGGATPVPRTLRKKLGTLFAFKKPRSTRGPRPDLETSPV-AAPRTRKTTLGDL
LRPPTRPSRGEES------------GGAEG-GISSPDSARRSRPRYTRDSKAYSMILLPA
EEE---EASLGFCPLRRP---LERGETELAPSFEQRVQVMLQRIGVSRGSGGAEGKRKQS
KDGEIKKAGSDGDIMDSSTEAPPISIKSRTHSVSADPSCRPGP---GGQGPESTTWKTLG
QQLNAELRGRGWGQQDGPGPP-------SP---CQS------PSPRRASPSPDSLGLPEE
PCLGPRNEDGQL-RPRPLSAGRRAVSVHEDQLQAPAERP----L----RLQRSPVLKRRP
KLEAPP-SPS-LGSGLGTEPLSREPTAPS--S-P------ERSTPSPATDQ-----RDGG
PN---P-----------

------------------------------------------MAQ-TPDGISCELRGEIT
RFLWPKEVELLLKTWLPG-EGA---VQNHVLALLRWRAYLLHTTCLPLRVDCTFSYLEVQ
AMALQETPPQVTFEL-ESLRELVLEFPGVAALEQLAQHVAAAIKKVFPCSTLGKLFRRPT
PASMLARLE-RRSPSEST--DPCSPCGGFLETYEALCDYNGFPFREEIQWDVDTIYHRQG
CRHFSLGDFSHLGS----RDLALSVAALSYNLWFRCLSCVDMKLSLEVSEQILHMMSQSS
HLEELVLETCGLRG--------------DFVRRLAQAMAGHS

PF13516 // ENSGT00390000014487_1_Domain_0 (343, 378)

SSGLRELSLAGNLLDDRG
M-------------AALSRHLERCPGALRRLSLAQTGLTPR-------------------
-------GMRALGRALATNA-TFDSALTHLDLSGNPGALGASEDSGGLYSFLS----RPN
VLSFLNLAGTDTALDTVRGCSVGGWMTG------RADWRAGRGGL-G-PPAGAANSLPSQ
LFAALSGGCCISLIHLDASRNVFSRTKSRAA-----PAAMQLFLSRARTLRHLGLA---G
CKLPPDALRALLDGLALNTHLRDLHLDLSACELRSAGAQVIQDLVCDAGAVSSLDLADNG
FGSDMVTLVLAIGRSRN---------FHVRCNLF-------------------SLCRLAE
SRLKLGASVLLRALA

PF13516 // ENSGT00390000014487_1_Domain_3 (736, 760)

TNP-NLTALDISGNAMGDAGAKLL

ENSGT00390000014487_1_Linker_3_4 (760, 977)

AKALRVNSRLR------WRRA
-----------GLNEALEQN-HSLKAMPLPLNDVAQAQRSRPELTARAVHQIQACLLRNN
RADPASSDHTTHLQPLGLVSDPSEQEVNELCQSVQEHVELLGCGAGPQGEAAVHQA----
-EDAIQNANFSLSILPILY----EAGSSPSHHWQLGQKLEGLLGQVGEVCRQDIK-----
-------DFTQATLDT

PF16000 // ENSGT00390000014487_1_Domain_4 (977, 1415)

ARSLCPQMLQGSSWREQLEGVLAGSRGL-----PELLPEQLLQD
AFTRLRDMRLSIT--GTLAESIVAQALAGLSAARDRVWL-------------SRQTVTMP
PALPAP-DRGEPSLLEPWEL------EGL--FFPEEN-E-E-------EKEKDDSPLQKW
PEL------------SHGLHLVPFIHSAAE-----------------------ETEPEPE
LAAPGEDAE---------------PQAGPSARGSPSPAAP---GPPAGPLPRMDL----P
PAGQ-P--------LRHPTR-ARPRPR-RQHHH---------------------------
------RPP---PGGPQVPPALPQE----GNGLSARVDEGVEEFFSKRLIQQDRLWAP--
EEDPAT-EGGATPVPRTLRKKLGTLFAFKKPRSTRGPRPDLETSPG-AAPRTRKTTFGDL
LRPPTRPSRGEEP------------GGAEG-DTSSPDPARRSRPRYTRDSKAYSMILLPA
EEE---ATLGARPDKRRP---LERGETELAPSFEQRVQVMLQRIGVSRGSGGAEGKRKQS
KDGEIKKAGSDGDIMDSSTEAPPISIKSRTHSVSADPSCRPGP---GNQGPESATWKTLG
QQLNAELRSRGWGQQDGPGPP-------SP---GQS------PSPCRTSPSPDSLGLPED
PCLGPRNEDGQL-RPRPLSAGRRAVSVHEDQLQAPAERP----L----RLQRSPVLKRRP
KLEAPP-SPS-LGSGLGTEPLPPQPTEPS--S-P------ERSPPSPATDQ-----RGGG
PN---P-----------

------------------------------------------MAQTPD-GISCELRGEIT
RFLWPKEAELLLKTWLPQ-EGA---EQSHILALLRWRAYLLH-TCLPLRVDCTFSYLEVQ
AMALQETPPQVTFEL-ESLPELVLEFPGVAALEQLAQHVAVAIKKVFPRSTLGKLFRKPT
PSSLLARLE-RSCPLEST--SPSSPCGGFLETYEALCDYNGFPFREEIQWDVDTIYHRQG
CRHFCLGDFAHLGS----RDLALSVAALSYNLWFRRLSCVDMKLSLEVSEQILHMMSQSS
HLEALVLETCGLRG--------------DFVRRLAQALAGH

PF13516 // ENSGT00390000014487_1_Domain_0 (342, 378)

SNSGLRELSLSGNLLDDRG
M-------------AALSRYLEHCPGALRRLSLAQTGLTPR-------------------
-------GMRALGRALAANA-TFDSTLTHLDLSGNPGALGASQDSGGLYTFLS----RPN
VLVFLNLAGTDTALG--------------------------------------------T
LFAALSGGCYSSLAHLEASRNVFSRTKSRAA-----PAALQHFLGSARMLQHLGLA---G
CKLPPEALRALLDGLALNTQIHDLHLDLSACELRSAGAQVIQDLVCDVGALSSLDLSDNG
FGSDMVTLVLAIGRSRSLKYVALGRNFNVRCKETLDDVLHRIVQLMQDDDCPLQSLSVAE
SRLKQGASVLLRALG

PF13516 // ENSGT00390000014487_1_Domain_3 (736, 760)

TNP-KLTALDISGNAIGDAGAKML

ENSGT00390000014487_1_Linker_3_4 (760, 977)

AKALRVNTRLRSV---IWDRN
NTSALGLLDVA---QALEEN-HSLKSMPLPLNDVTQAHRSRPELTAQAVHQIQACLLRNN
REDP-ASDLKPCLQPLGLISEHSEQEVNELCQSVQEHVELLGCGAGPQGEVAVHQA----
-EDAIQNANFSLSILPILY----EAGSSPSHHWQLHQKLEGLLGQVGEICRQDIQ-----
-------DFTQTTLDT

PF16000 // ENSGT00390000014487_1_Domain_4 (977, 1415)

TRSLCPQMLQRPSWKEQLEGVLVGSRSL-----PELLPEHLLQD
AFTRLRDMRLSIT--GTLAENIVAQALEGLHTARDRLVES----------LAEQSAVTVD
PAVPSL-DVHELSPLETGGL------EDL--FFPMEKEEER-ED---------NGSSWKW
LEP------------SYCFHLV----------------------PSL-HGTAEEAERDPE
LAAPGEDAEPQA---------------GPSARGSPSPAAP---GPPAGPLPRMDL----P
PAGQ-P--------LRH-PTRARPRPR-RQHHH---------------------------
------RPP---PGGPQVSPALLQE----GNGLTARVDEGVEEFFSKRLIQQDRLWAL--
EEDPAT-EGGATPVPRTLRKKLGTLFAFKKPRSTRGPRSDLETSPG-ATARARKTTLGDL
LRPPARPSRG-EEP-----------GGAEG-GTSSPDSTRRNRPRYTRESKAYSMILLPA
EEE--EATVGARSDKRRP---LERGDTELAPSFEQRVQVMLQRIGVSRGSGGAESKRKQS
KDGEIKKAGSDGDIMDSSTETPPISIKSRTHSVSADPSCRPGP---GGQGPESATWKTLG
QQLNAELRGRGWGQQDGPGPP-------SP---CPS------PSPRRTSPSPDILSLPED
PCLGPRSEDGQL-RPRPLSAGRRAVSVHEDQLQTPSERP----L----RLQRSPVLKRRP
KLEAPP-SPS-LGSGLGTKPLFPYPTESS--S-P------ERSPPSPATDQ-----RGGG
PN----P----------

------------------------------------------MA-QIPDGISCELRGEIT
RFLWPKEAELLLKTWLPQ-EGA---ERSHVLALLRWRAYLLH-TCIPLRVDCTFSYLEVR
AMALQETPPQVTFEL-ESLPELVLEFPGVATLEQLAQHVASAIKKVFPRSALGKLFRKPT
PASMLARLE-RSSPSEST--ALSSPCGGFLETYEALCDYNGFPFREEIQWDVDTVYHHQG
CRQFSLGDFSHLGS----RDLALSVAALSYNLWFRCLSCVDMKLSLEVSEQILHMMGQSS
HLEELVLETCGLRG--------------DFVRRLAQALAGHS

PF13516 // ENSGT00390000014487_1_Domain_0 (343, 378)

SSGLRELSLAGNLLDDRG
M-------------AALSRHLEHRPGALRRLNLAQTGLTPR-------------------
-------GMRALGQALATNA-TFDSALTHLDLSWNPGALGASEDNGGLYTFLS----RPN
VLMFLNLAGTDAALDT--------------------------------------------
LFTALASGCCSSLTYLDTSRNVFSHCKSRAA-----PASLQLFLSHAETLRHLGLA---G
CKLPPEALRAVFDGLALNTHIRDLHLDLSACELRSAGAQVIQDLVCDAGVMSSLDLEDNG
FGSDMVTLVLAIGRSRSLKHVALGRNFNVRCKETLDDVLHRIVQLMQDDDCPLQSLSVAD
SRLKLGASVLLRALGA

PF13516 // ENSGT00390000014487_1_Domain_3 (737, 760)

NP-SLTALDISGNAIGDTGAKMLAKALRVNTRLRSV---IWDRN
HTSALGLLDVA---QALEQN-HSLKDMPLPLNDVAQAQRSRPELTARAVHQIQACLLRNN
REDPASSGHSSCLQPLNLDSNHSEQEVNELCQSVQEHMELLGCGAGPQGEAAVHQA----
-EDAIQNANFFLSILPILS----EAGNSPSYQWQLRQKLEALLGQVGEICHQDMQ-----
-------DFIRAILDTTRSLCRQMLQGPGWREQLEGVLVGSKGL-----SELLPEQLLQD
AFTRLRDMRLSVT--GTLAESIVAQALAGLRAAQDRLVES----------LAQQVPVAVP
PSLPAL-DGGELSPLGPGAL------EGF--FFAEDKEDEE---------EKDESPLRKW
PE--------------HCLHPVPFD-----------------------------------
------------------------------------------------------------
------------------------------

PF16000 // ENSGT00390000014487_1_Domain_4 (1291, 1415)

HHH---------------------------
------RPP---PGGPQVPPALPQE----GNGLSARVDEGVEEFFSKRLIQQDRLWAP--
E-EDPATEGGATPVPRTLRKKLGTLFAFKKPRSTRGPRPDLETSPG-AAARTRKTTLGDL
LRPPARPGRGEES------------GGAEG-GPSSPDPARRSRPRYTRESKAYSMILLPA
EEE---ETLNARPDKRRP---LERGDTELAPSFEQRVQVMLQRIGVSRGSGGAEGKRKQS
KDGEIKKAGSDGDIMDSSIETPPISIKSRTHSVSADPSCRPGP---GAQGPESATWKTLG
QQLNAELRGRGWGQQDGPGPP------SSP---CPS------SNLRRASPA-DSLGLPED
PCLGPRNEDGQL-RPRPLSAGRRAVSVHEDQLQAPAERP----L----RLQRSPVLKRRP
KLEAPL-SPS-LGSGLGTEPLPPQPTEPS--S-P------EQSPPSPATDQ-----RGGG
PN---P-----------

------------------------------------------MA-QTPDGISCELRGEIA
RFLWPKEAELLLKTWLPQ-EGA---ERSYVLVLLRWRVYLLH-TCLPLRVSPRAW-----
-LPQPFCPSQVTFEL-ESLPELVLEFPDVAALERLAQHVAVAIKKVFPRSTLGLGLL---
------------------------FLRGFLETYEALCDYNGFPFREEIQWDVDTIYHRQG
CRHFSLGDFSHLGS----RDLALSVAALSYNLWFRCLSCVDMKLSLEVSEQILHMMSQSS
HLEELVLETCGLRG--------------DFVRRLAQALAGHS

PF13516 // ENSGT00390000014487_1_Domain_0 (343, 378)

SSGLRELSLAGNLLDDRG
V-------------AALSRHLEHCPGALRRLSLAQTGLTPR-------------------
-------GMRALGRALAANA-AFDSALTHLDLSGNPGALGASEDSGVSGCLQGWSLGWPQ
AVGCQDAPGK-PPLTPSHSWGGQWGMMG------RQDRLEGGDGH--GPSAGVADTLLPQ
LFAALSRGCCTNLTHLDASRNVFSRTKSRAA-----PAALQLFLGRAGTLRHLSLA---G
CKLPPDALRALLDGLALNTHLRDLHLDLSACELRSAGAQVIQDLVCDAGAVSSLDLADNG
FGSDMVTLVLAIGRSRSLRHVALGRNFNVRCKETLDDVLHRIVQLMQDDDCPLQSLSVAE
SRLKLGASVLLRALGA

PF13516 // ENSGT00390000014487_1_Domain_3 (737, 760)

NP-NLTALDISGNAMGDVGAKML

ENSGT00390000014487_1_Linker_3_4 (760, 977)

AKA---------VGSVVWDRN
NTSALGLLDVA---QALEHN-HSLKSMPLPLNDVAQAQRSRPELTARAVHQIQACLLRNN
RADPASSDRLSQLQPLSLVSNPSEQEVNELCQSVQEHMELLGCGAGPQGEAAVHQA----
-EDAIQNANFSLSILPILY----EAGSSPSHHWQLRQKLEGLLRQVGEVCRQEIQ-----
-------DFTQATLDT

PF16000 // ENSGT00390000014487_1_Domain_4 (977, 1415)

TRSLCPQMLQGSGWREQLEGVLVGSRGF-----PELLPEQLLQN
AFTRLRDMRLSVT--GTLAESIVAQALAGLSAARDRLVES----------LAQQATVVVP
SALPTL-DGGEPSPLGPGEL------EGL--FFPEEKEEEE---------EEKDDSSRKW
PEP------------SHGLRPASSIHSAAE-------------------------EQEPE
LAAPGEDAE---------------PQAGPSARGSPSPAAP---GPLAGPLPRMDL----P
PAGQ-P--------LRHPTR-ARPRPR-RQHHH---------------------------
------RPP---PGGPQVPPALPQE----GNGLSARVDEGVEEFFSKRLIQQDRLWAS--
EEDPAT-EGGATPVPRTLRKKLGTLFAFKKPRSTRGPRPDLETSPV-AAPRTRKTTLGDL
LRPPTRPSRGEES------------GGAEG-GISSPDSARRSRPRYTRDSKAYSMILLPA
EEE--EAMLGARPDKRRP---LERGETELAPSFEQRVQVMLQRIGVSRSSGGAEGKRKQS
KDGEIKKAGSDGDIMDSSTETPPISIKSRTHSVSADPSCRPGP---GGQGPES-TWKTLG
QQLNAELRGRGWGQQDGPGPP-------SP---CQS------PSPRRASPSPDSLGLPEE
PCLGPRNEDGQL-RPRPLSAGRRAVSVHEDQLQAPAERP----L----RLQRSPVLKRRP
KLETPP-SPS-LGSGLGTQPLPPQPTEPS--S-P------ERSPSSPATDQ-----RDGG
PN---P-----------

------------------------------------------MA-QTPDGISCELRGEIT
KFLWPKEVELLLKTWLPG-EGA---VQNHVLALLRWRAYLLHTTCLPLRVDCTFSYLEVQ
AMALQETPPQVTFEL-ESLRELVLEFPGVAALEQLAQHVAVAIKKVFPCSTLGKLFRRPT
PASMLARLE-RSSPSEST--DPCSPCGGFLETYEALCDYNGFPFREEIQWDVDTIYHRQG
CRHFSLGDFSHLSS----RDLALSVAALSYNLWFRCLSCVDMKLSLEVSEQILHMMSQSS
HLEELVLETCGLRG--------------DFVRRLAQVLAGHS

PF13516 // ENSGT00390000014487_1_Domain_0 (343, 378)

SSGLRELSLAGNLLDDRG
M-------------AALSRYLEGCPGG---------------------------------
-------------GALAANA-AFDSILTQLDLSGNPGALGPSEDSGGLYTFLS----RPN
VLSFLNLAGTDTALDTVRGCSVGRWMIC------RADWRVGREGG---------------
LFAALSRGCCPSLTHLDASRNVFSRTKSRAA-----PAALQLFLSRVGTLRHLGLA---G
CKLPPDALRALLDGLALNMHLRDLHLDLSACELRSAGAQVIQDLVCDAGAVSSLDLADNG
FGSDMVTLVLAIGRSRSLRHVALGRNFNVRCKETLDDVLHRIVQLMQDDDCPLQSLSVAE
SRLKLGASVLLRALA

PF13516 // ENSGT00390000014487_1_Domain_3 (736, 760)

TNP-NLTALDISGNAVGDAGAKLL

ENSGT00390000014487_1_Linker_3_4 (760, 977)

AKALRVNSRLRSV---VWDRN
HTSALGLLDVA---QALEQN-HTLKAMPLPLNDVAQAQRSRPELTARAVHQIQACLLRNN
RADPASSDHTAHLQPLSLVSGPSEQEVNELCQSVQEHVELLGCGAGPQGEAAVRQA----
-EDAIQNANFSLSILPILY----EAGSSPSYHWQLGQKLEGLLGHVGEVCRQDIQVSWFD
PHPIVLTDFTQATLDT

PF16000 // ENSGT00390000014487_1_Domain_4 (977, 1415)

ARNLCPQMLPGSSWREQLEGVLAGLRGL-----PELLPEQLLQD
AFTRLRDMRLSIT--GTLAESIVAQALAGLSAARDRLVEN----------LAQQATVTMP
PSLPVL-NGGQPSPLEPGEL------EGL--FFSKEEKEEE-------EEEKDDSPARKW
PEL------------SHSLYLVPFIHSKSG-----------------------SWERDSP
LDMGTRGPGQTH-------------------------------SALSGYTPALDW----P
SQA----------------RIPMQPAKLRSHHH---------------------------
------RPP---PGGPQVSTLPRLP----S-----------AWIWGS---RVAQPWAP--
EEDPAT-EGGTTPVPRTLRKKLGTLFAFKKPRSTRGPRPDPETSPG-AAPRTRKTTFGDL
LRPPTRPSRGEEP------------GGAEG-DTSSPDPARRSRPRYTRDSKAYSMILLPA
EEE---AMLGARPDKRRP---LERGETELAPSFEQRVQVMLQRIGVSRGSGGAEGKRKQS
KDGEIKKAGSDGDIMDSSTEAPPISMKSRTHSVSADPSCRPGP---GSHGPESATWKTLG
QQLNAELRSRGWGQQDGPGPP-------SP---GQS------PSSCRASPSPDSLGLPED
PCLGPRSEGQGMDRPQAL-------SNPPQAFLCSLERP----L----RLQRSPVLKRRP
KLEAPP-SPS-LGSGLGTEPLHPKPTEPS--S-P------ERSPPSPATDQ-----RGGG
PN---P-----------

SAAGGAGGCSARRGPRLPV-SP-RYRFSSELLGPPGPG--RPMAQTPD-GISCELRGEIT
RFLWPKEAELLLKTWLPEREGA---EQGHVLALLRWRAYLLH-TCLPLRVDCTFSYLEVQ
AMALQETPPQVTFEL-ESLPDLVLEFPGVAALEQLAQHIAAAIRKVFPCSTLGKLFRRPT
PPSMLARLE-RSSPSEAT--SPSSPCGGFSETYEALCDYNGFPFREEIQWDVDTIYHRQG
CRHFSLGDFSHLGS----RDLALSVAALSYNLWFRCLSCVDMKLSLEVLEQILHMMSQSS
HLEELVLETCGLRG--------------DFVRRLAQALAGHTSSGLRELSLAGNVLDDRG
V-------------AALSRHLEHHPGALRRLTLAQTGLTPR-------------------
-------GMRALGRALAFNA-AFDSALTHLDLSGNPGALGASEDNGGLYSFLS----RPN
VLTFLNLAGTDTALDTVRGWSVGGMICRAGKAGPRVDWRA--GREGLSPPASVAHTLLPQ
LFASLSRGCCA

PF00560 // ENSGT00390000014487_1_Domain_2 (552, 583)

SLTHLDASRNVFSRTKSRAA-----PDALQLFLSRAETLRYLCLA---G
CKLPPDALRALLEGLALNTHMDDLHLDLSACELRSAGAQVIQDLVCDAGAVSSLDLADNG
FGSDMVTLVLAIGRSRSLRHVALGRNFNVRCKETLDDVLHRIVQLMQDDDCPLQSLSVAE
SRLKLGASVLLRALGANP-NLTALDISGNAMGDTGAKMLAKALRVNTRLRSV---VWDRN
HTSALGLLDVA---QALEQN-RSLKAMPLPLNDVAQAQRSRPELTARAVHQIQACLLRNN
RADHASTDCTSHPKPLGLGSDPSEQEVNELCQSVQEHVELLGCGAGPQGEAAVHQA----
-EDAIQNANFSLSILPILH----EAGSSPSHQWQLRQKLEGLLGQVGEVCRRDIQ-----
-------DFTQTTLDTTRSLCPQMLQGPRWREQLEGVLGGSGGL-----PELLPEHLLQD
AFTRLRDMRLSVT--GTLAESIVAQAVAGLSAARDRLVES----------LAQQATEATP
PVIPAL-DGGEPSPLGPGEL------EGL--FFPEEKEKE--NEEEQKDD----SPPQKW
PES------------NRCLHLVPSTHSAA-------------------EEPEPEP----E
LAAPGEDAEPQA---------------GPSARGSPSPAAP---GPPAGPLPRMDL----P
PAG-QP--------LRH-PTRARPRPR-RQHHH---------------------------
------RPP---PGGPQVPPALPQE----GNGLSARVDEGVEEFFSKRLIHQDRLWAP--
EEDPAA-EGGTTPVPRTLRKKLGTLFAFKKPRSTRASRPDLETSPG-AAPRSRKTTLGDL
LRPPARPGRGEEA------------GGAEG-GTSSPDPTRRSRPRYTRESKAYSMILLPA
EEE--ETTLGARPDKQQP---LERGDTELAPTFEQRVQVMLQRIGVSRGSGSAEGKRKQS
KDGEIKKAGSDGDIMDSSTEAPPISIKSRTHSVSADPSCRPGP---GGQGPESATWKTLG
QQLNAELRGRGWGQQDGPGPP-------SP---CPS------PSLRRASPSPDSLGLPED
SCLGSRNEDGQL-RPRPLLAGRRAVSVHEDQLQAPVERP----R----RLQRSPVLKRRP
KLEASP-SPS-IGSGLGAEPLPPQSTEPS--D-P------ERSPPSPATD-----QRGGG
PN---P-----------

------------------------------------------MAQ-TPDGISCELRGEIT
RFLWPKEVELLLKTWLPG-EGA---VQNHVLALLRWRAYLLHTTCLPLRVDCTFSYLEVQ
AMALQETPPQVTFEL-ESLRELVLEFPGVAALEQLAQHVAAAIKKVFPRSTLGKLFRRPT
PASMLARLE-RSSPLEST--GPCSPCGGFLETYEALCDYNGFPFREEIQWDVDTIYHRQG
CRHFSLGDFSHLGS----RDLALSVAALSYNLWFRCLSCVDMKLSLEVSEQILHMMSQSS
HLEELVLETCGLRG--------------R-------------------------------
-------------------HLERCPGALRRLSLAQTGLTPRGRLDEGGGEGRGVGSAQLL
SYPTPPPGMRALGRALATNA-AFDSALTHLDLSGNPGALGSSEDSGGLYSFLS----RPN
VLSFLNLAGTDTALDTVRGCSVGGWMTD------RADWRAGQGGL-G-PPAGAANSLPPQ
LFAALSRGCCTSLTHLDASRNVFSRTKSRAA-----PAALQLFLSRARTLRHLGLA---G
CKLPPDALRALLDGLALNTHLRDLHLDLSACELRSAGAQVIQDLVCDAGAVSSLDLADNG
FGSDMVTLVLAIGRSRSLRHVALGRNFNVRCKETLDDVLHRIVQLMQDDDCPLQSLSVAE
SRLKLGASVLLRALA

PF13516 // ENSGT00390000014487_1_Domain_3 (736, 760)

TNP-NLTALDISGNAMGDAGAKLL

ENSGT00390000014487_1_Linker_3_4 (760, 977)

AKALRVNSRLRSV---VWDRN
HTSALGLLDVA---QALEQN-HSLKAMPLPLNDVAQAQRSRPELTARAVHQIQACLLRNN
RADPASSDHTTCLQPLGLVSDPSEQEVNELCQSVQEHVELLGCGAGPQGEAAVHQA----
-EDAIQNANFSLSILPILY----EAGSSPSHHWQLGQKLEGLLGQVGEVCRQDIQ-----
-------DFTQATLDT

PF16000 // ENSGT00390000014487_1_Domain_4 (977, 1415)

ARSLCPQMLQGSSWREQLEGVLAGSRGL-----PELLPEQLLQD
AFTRLRDMRLSIT--GTLAESIVAQALAGLSAARDQLVES----------LAHQATVIMP
SALPAP-DGGEPGLLEPGEL------GGL--FFPEEEKE-E-------EEEKDDSPPQKW
PEL------------SHGLHLVPFIQSKAT-----------------------------S
WRLSGEDAE---------------PQAGPSARGSPSPAAP---EGPRRHAA-YSL----P
PAAA-R--------LRQSIYPKTRPPA-RQHHH---------------------------
------RPP---PGGPQVPPALPQE----GNGLSARVDEGVEEFFSKRLIQQDRLWAP--
EEDPAT-EGGATPVPRTLRKKLGTLFAFKKPRSTRGPRPDLETSPG-AAPRTRKTTFGDL
LRPPTRPSRGEEP------------GGAEG-DTSSPDPARRSRPRYTRDSKAYSMILLPA
EEE---ATLGARPDKRRP---LERGETELAPSFEQRVQVMLQRIGVSRGSGGAEGKRKQS
KDGEIKKAGSDDRCSDLSPRPDQV---LADTLLPTDPSCRPCP---GSQGPESATWKTLG
QQLNAELRSRGWGQQDGPGPP-------SP---GQS------PSPCRTSPSRDSLGLPED
PCLGPRNEDGQL-RPRPLSAGRQAVSVHEDQLQAPAERP----L----RLQRSPVLKRRP
KLEAPP-SPS-LGSGLGTEHLPPQPTESS--S-P------ERSPPSPATDQ-----RGGG
PS---P-----------

------------------------------------------MAQ-TPDGISCELRGEIT
RFLWPKEVELLLKTWLPG-EGA---VQNHVLALLRWRAYLLHTTCLPLRVDCTFSYLEVQ
AMALQETPPQVTFEL-ESLRELVLEFPGVAALEQLAQHVAAAIKKVFPRSTLGKLFRRPT
PASMLARLE-RSSPSEST--DPCSPCGGFLETYEALCDYNGFPFREEIQWDVDTIYHRQG
CRHFSLGDFSHLGS----RDLALSVAALSYNLWFRCLSCVDMKLSLEVSEQILHMMSQSS
HLEELVLETCSLRG--------------DFVRRLAQALAGHS

PF13516 // ENSGT00390000014487_1_Domain_0 (343, 378)

SSGLRELSLAGNLLDDRG
M-------------TALSRHLERCPGALRRLSLAQTGLTPR-------------------
-------GMRALGRALATNA-AFDSTLTHLDLSGNPGALGASEDSGGLYSFLS----RPN
VLSFLNLAGTDTALDTVRGCSVGGWMTG------RADWRAGRGGL-G-PPAGVANSLPPQ
LFAAVSRGCCTSLTHLDASRNVFSRTKSRAA-----PAALQLFLSRARTLRHLGLA---G
CKLPPDALRALLDGLALNTHLRDLHLDLSACELRSAGAQVIQDLVCDAGAVSSLDLADNG
FGSDMVTLVLAIGRSRSLRHVALGRNFNVRCKETLDDVLHRIVQLMQDDDCPLQSLSVAE
SRLKLGASVLLRALA

PF13516 // ENSGT00390000014487_1_Domain_3 (736, 760)

TNP-NLTALDISGNAMGDAGAKLL

ENSGT00390000014487_1_Linker_3_4 (760, 977)

AKALRVNSRLRSV---VWDRN
HTSALGLLDV---AQALEQN-HSLKAMPLPLNDVAQAQRSRPELTARAVHQIQACLLRNN
RADPASSDHTTRLQPLGLVSDPSEQEVNELCQSVQEHVELLGCGAGPQGEAAVRQA----
-EDAIQNANFSLSILPILY----EAGSSPSHHWQLGQKLEGLLRQVGEVCRQDIQ-----
-------DFTQATLDT

PF16000 // ENSGT00390000014487_1_Domain_4 (977, 1415)

ARSLCPQMLQGSSWREQLEGVLAGSRGL-----PELLPEQLLQD
AFTRLRDMRLSIT--GTLAESIVAQALAGLSAARDQLVES----------LAQQATVTMP
PALPAP-DGGEPSLLEPGEL------EGL--FFPEEK-E-E-------EKEKDDSPPQKW
PEL------------SHGLHLVPFIHSAAE-----------------------EAEPEPE
LAAPGEDAE---------------PQAGPSARGSPSPAAP---GPPAGPLPRMDL----P
LAGQ-P--------LRHPTR-ARPRPR-RQHHH---------------------------
------RPP---PGGPQVPPALPQE----GNGLSARVDEGVEEFFSKRLIQQDRLWAP--
EEDPAT-EGGATPVPRTLRKKLGTLFAFKKPRSTRGPRTDLETSPG-AAPRTRKTTFGDL
LRPPTRPSRGEEL------------GGAEG-DTSSPDPAGRSRPRYTRDSKAYSMILLPA
EEE---ATLGARPDKRRP---LERGETELAPSFEQRVQVMLQRIGVSRGSGGAEGKRKQS
KDGEIKKAGSDGDIMDSSTEAPPISIKSRTHSVSADPSCRPGP---GSQGPESATWKTLG
QQLNAELRSRGWGQQDGPGPP-------SP---GQS------PSPCRTSPSPDSLGLPED
PCLGPRNEDGQL-RPRPLSAGRRAVSVHEDQLQAPAERP----L----RLQRSPVLKRRP
KLEAPP-SPS-LGSGLGTEPLPPQPTEPS--S-P------ERSPPSPATDQ-----RGGG
PN---P-----------

------------------------------------------MA-QTPDCISCELRGEIT
RFLWPKEAELLLKTWLPQ-EGV---ERSYILALLRWRAYLLH-TSLPLRVDCTFSYLEVQ
AMTLQETPPQVTFEL-ESLPDLVLEFPGVAILEQLAQHVASAIKKVFPRSALGKLFRKPT
PPSMLARLG-KSISSESA--TPSSPCGKASCSYFL------------PIQDVDTIYHRQG
CRQFNLGDFSHLGS----RDLALSVAALSYNLWFRCLSCVDMKLSLEVSEQILYMMGQSS
HLEELVLETCGLKG--------------DFVRRLAHALAGHS

PF13516 // ENSGT00390000014487_1_Domain_0 (343, 377)

CSGLRELSLAGNLLDDRG
M-------------VALGRHLEQRPGALRRLSLAQTGLTSR-------------------
-------GMRALGRALACNA-AFDSALTHLDLSGNPGALGASEDNGGLYSFLS----RPN
FLMFLNLAGTDAALDTVRGVR--------------GVWRAGGGGK-G-LVLSLANTLLLQ
LFEALSRGCCASLTHLDTSRNVFSRCKSQAA-----PAPLQLFLSHAETLRYLGLA---G
CKLPHEALRAVFDGLALNTHIQDLHLDLSACELRSAGAQVIQDLVCDAGVVSSLDLADNG
FGSDMVTLVLAIGRSRSLRHVALGRNFNVRCKETLDDVLHRIVQLMQDDDCPLQSLSVAD
SRLKLGASVLLRALG

PF13516 // ENSGT00390000014487_1_Domain_3 (736, 760)

TNP-NLTALDISGNAMGDPGAKML

ENSGT00390000014487_1_Linker_3_4 (760, 977)

AKALRVNTRLRSV---IWDRN
HTSALGLLDVA---QALEQN-HSLKAMPLPLNDVAQAQRSRPELTARAVHQIQACLLRNN
REDPTSSGLTSCLQPLNLVSEHSEQEVNELCQSVQEHMELLGCGSGPQSEAAVHQA----
-EDAIQNANFFLSILPILN----EAGNSPSHHWQWRQKLEALLEQLGEVCHKDIQ-----
-------DFIQAILD-

PF16000 // ENSGT00390000014487_1_Domain_4 (977, 1415)

TRSLCPQMLQGPGWKKQLEGVLVDSKGL-----PGLLPEQLLQD
AFIRLRDVRLSERQCRTLAESIVAQALAGLNAARDRLVES----------LAQQAPVSMP
PDLPAL-DGGEPSPLEPGAL------EGF--FFLEDKE------------EKDESPLRKW
PEH------------NHCLHWVSFDHSAAE-----------------------EAEPEPE
LAAPGEDAE---------------PQAGPSARGSPSPAAP---GPPAGPLPRMDL----P
PAGQ-P--------LRHPTR-ARPRPR-RQHHH---------------------------
------RPP---PGGPQVPPALPQE----GNGLSSRVDEGVEEFFSKRLIQQDRLWAP--
EEDLAT-EGGATPVPRTLRKKLGTLFAFKKPRSTRGPRPDLETSLG-AAARTRKTTLGDL
LRPPARPGRGEEP------------GGAEG-GPSSPDPARRSRPRYTRESKAYSMILLPA
EEE---ETLNARPDKRRP---LERGDTELAPSFEQRVQVMLQRIGVSRGSGSAEGKRKQK
GQRGGRGGERKG--------EEKTIIISKLTLFPADPSCRPGT---GAQGPEPATWKTLG
QQLNAELRGRGWGQQDGPGPP-------SP---CPS------PNLRRASPAPDILGLPED
PCLGPRNEDGQL-RPRPLSAGRRAVSVHEDQLQAPAERP----L----RLQRSPVLKRRP
KLEAPP-SPS-LGSGLGTEPLPPRPTEPSSPS-P------EQNPPSPATDQ-----RGGG
PN---P-----------

------------------------------------------MAQ-TPDGISCELRGEIT
RFLWPKEVELLLKTWLPG-EGA---VQNHVLALLRWRAYLLHTTCLPLRVDCTFSYLEVQ
AMALQETPPQVTFEL-ESLRELVLEFPGVAALEQLAQHVAAAIKKVFPRSTLGKLFRRPT
PASMLARLE-RSSPLEST--GPCSPCGGFLETYEALCDYNGFPFREEIQWDVDTIYHRQG
CRHFSLGDFSHLGS----RDLALSVAALSYNLWFRCLSCVDMKLSLEVSEQILHMMSQSS
HLEELVLETCGLRG--------------DFVRRLAQALAGHS

PF13516 // ENSGT00390000014487_1_Domain_0 (343, 378)

SSGLRELSLAGNLLDDRG
M-------------AALSRHLERCPGALRRLSLAQTGLTPR-------------------
-------GMRALGRALATNA-AFDSALTHLDLSGNSGALGSSEDSGGLYSFLS----RPN
VLSFLNLAGTDTALDTVRGCSVGGWMTD------RADWRAGQGGL-G-PPAGAANSLPPQ
LFAALSRGCCTSLTHLDASRNVFSRTKSRAA-----PAALQLFLSRARMLRHLGLA---G
CKLPPDALRALLDGLALNTHLRDLHLDLSACELRSAGAQVIQDLVCDAGAVSSLDLADNG
FGSDMVTLVLAIGRSRSLRHVALGRNFNVRCKETLDDVLHRIVQLMQDDDCPLQSLSVAE
SRLKLGASVLLRALA

PF13516 // ENSGT00390000014487_1_Domain_3 (736, 760)

TNP-NLTALDISGNAMGDAGAKLL

ENSGT00390000014487_1_Linker_3_4 (760, 977)

AKALRVNSRLRSV---VWDRN
HTSALGLLDV---AQALEQN-HSLKAMPLPLNDVAQAQRSRPELTARAVHQIQACLLRNN
RADPASSDHTTCLQSLGLVSDPSEQEVNELCQSVQEHVELLGCGAGPQGEAAVRQA----
-EDAIQNANFSLSILPILY----EAGSSPSHHWQLGQKLEGLLGQVGEVCRQDIQ-----
-------DFTQATLDT

PF16000 // ENSGT00390000014487_1_Domain_4 (977, 1100)

ARSLCPQMLQGSSWREQLEGVLAGSRGL-----PELLPEQLLQD
AFTRLRDMRLSIT--GTLAESIVAQALAGLSAARDQLVES----------LAHQATVTIP
SALPAP-DGGEPGLLEPGEL------GGL--FFPEEK-E-E-------EEEKDDSPPQKW
PEL------------SHGLHLVPFIQ----------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------VPPALPQE----GNGLSARVDEGVEEFFSKRLIQQDRLWAP--
EEDPAT-EGGATPVPRTLRKKLGTLFAFKKPRSTRGPRPDLETSPG-AAPRTRKTTFGDL
LRPPTRPSRGEEP------------GGAEG-DTSSPDPARRSRPRYTRDSKAYSMILLPA
EEE---ATLGARPDKRRP---LERGETELAPSFEQRVQVMLQRIGVSRGSGGAEGKRKQS
KDGEIKKAGSDGDIMDSSTEAPPISIKSRTHSVSADPSCRPCP---GSQGPESATWKTLG
QQLNAELRSRGWGQQDGPGPP-------SP---GQS------PSPCRTSPSRDSLGLPED
PCLGPRNEDGHL-RPRPLSAGRRAVSVHEDQLQAPAERP----L----RLQRSPVLKRRP
KLEAPP-SPS-LGSGLGMEHLSPQPTEPS--S-P------ERSPPSPATDQ-----RGGG
PS---P-----------

------------------------------------------MAQ-TPDGISCELRGEIT
RFLWPKEVELLLKTWLPG-EGA---VQNHVLALLRWRAYLLHTTCLPLRVDCTFSYLEVQ
AMALQETPPQVTFEL-ESLRELVLEFPGVAALEQLAQHVAAAIKKVFPRSTLGKLFRRPT
PASMLARLE-RSSPSEST--DPCSPCGGFLETYEALCDYNGFPFREEIQWDVDTIYHRQG
CRHFSLGDFSHLGS----RDLALSVAALSYNLWFRCLSCVDMKLSLEVSEQILHMMSQSS
HLEELVLETCSLRG--------------DFVRRLAQALAGHS

PF13516 // ENSGT00390000014487_1_Domain_0 (343, 378)

SSGLRELSLAGNLLDDRG
M-------------TALSRHLERCPGALRRLSLAQTGLTPR-------------------
-------GMRALGRALATNA-AFDSTLTHLDLSGNPGALGASEDSGVS------------
------------------GCLQGGSL-----------------GV-G-PRPRPRGRSQPA
LAFAPPRSCFCRSHNLPQI---------LAL-----PPSF----APWSPLSQLPPP---R
---VTSPPRALLDGLALNTHLRDLHLDLSACELRSAGAQVIQDLVCDAGAVSSLDLADNG
FGSDMVTLVLAIGRSRSLRHVALGRNFNVRCKETLDDVLHRIVQLMQDDDCPLQSLSVAE
SRLKLGASVLLRALA

PF13516 // ENSGT00390000014487_1_Domain_3 (736, 760)

TNP-NLTALDISGNAMGDAGAKLL

ENSGT00390000014487_1_Linker_3_4 (760, 977)

AKALRVNSRLRWAGSEGWDQR
AGG-AGLNEAEQMESVVWDR-NHTSAMPLPLNDVAQAQRSRPELTARAVHQIQACLLRNN
RADPASSDHTTRLQPLGLVSDPSEQEVNELCQSVQEHVELLGCGAGPQGEAAVRQA----
-EDAIQNANFSLSILPILY----EAGSSPSHHWQLGQKLEGLLRQVGEVCRQDIQ-----
-------DFTQATLDT

PF16000 // ENSGT00390000014487_1_Domain_4 (977, 1138)

ARSLCPQMLQGSSWREQLEGVLAGSRGL-----PELLPEQLLQD
AFTRLRDMRLSIT--GTLAESIVAQALAGLSAARDRLVES----------LAQQATVTVP
PALPAP-DGGEPSLLEPGEL------EGL--FFPEEKEE---------EKEKDDSPPQKW
PEL------------SHGLHLVPFIHSKSG-----------------------PWGREFT
WAMPVRDHGCAGSV-------RGVPGCGTPSRGGPRPPWLRERGCPSSLPPPGLL----R
DAGQ-P--------GSR---AAGPSLRLLRVRR---------------------------
------RRV---WGDACVPPALPQE----GNGLSARVDEGVEEFFSKRLIQQDRLWAP--
EEDPAT-EGGATPVPRTLRKKLGTLFAFKKPRSTRGPRTDLETSPG-AAPRTRKTTFGDL
LRPPTRPSRGEEP------------GGAEG-DTSSPDPARRSRPRYTRDSKAYSMILLPA
EEE---ATLGARPDKRRP---LERGETELAPSFEQRVQVMLQRIGVSRGSGGAEGKRKQS
KDGEIKKAGSDGDIMDSSTEAPPISIKSRTHSVSADPSCRPGP---GSQGPESATWKTLG
QQLNAELRSRGWGQQDGPGPP-------SP---GQS------PSPCRTSPSPDSLGLPED
PCLGPRNEDGQL-RPRPLSAGRRAVSVHEDQLQAPAERP----L----RLQRSPVLKRRP
KLEAPP-SPS-LGSGLGTEPLPPQPTEPS--S-P------ERSPPSPATDQ-----RGGG
PN---P-----------

------------------------------------------MA-QTPDGISCELRGEIT
RFLWPKEVELLLKAWLPEQEGA---DRSHVLALLRWRAYLLH-TCLPLRVDCTFSYLEVQ
AMALQETPPQVTFEL-ESLPELVLEFPGVTALEQLAQHITVAIKKVFPRSALGKLFRRPT
PPSMLAQLE-RSSPSEAT--TPGSPCGGFLETYEALCDYNGFPFREEIQWDVDTIYHGQG
CRHFSLGDFSHLSS----RDLALSVAALSYNLWFRCLSCVDMKLSLEVSEQILHMMSQSS
HLEELVLETCGLRG--------------DFVRRLAQALAGNPSSGLQELSLAGNLLDDR-
------------------------------------------------------------
-------GMRALGEALATNV-AFDSSLTHLDLSANPGALGPSEDNGGLYSFLS----RPN
VLTFLNLAGTDTALDT--------------------------------------------
LFAALSRGCCANLTHLEASRNVFSRTKFRAA-----PATLQLFLSRAGALRHLGLA---S
CKLPPDALRALLEGLALNTHIGDLHLDLSACELRSAGAQVIQDLVCDAGAVSSLNLADNG
FGSDMVTLVLAIGRSRSLRHVALGRNFNVRCKETLDDVLHRIVQLMQDDDCPLQSLSVAE
SRLKLGASVLLRALGTNP-

PF00560 // ENSGT00390000014487_1_Domain_3 (740, 766)

NLTELDISGNAMGDTGAKMLAKALRVNTRLRSV---VWDRN
HTSALGLLDVA---QALEQN-RSLKAMPLPLHDVAQAQRSRPELTAHAVHQIQACLLRNN
RTDPASSDRAFRLQPQGLVSNPSKQEVNELCQSVQEHMELLGCGAGPQGEAAVRQA----
-EDAIRNANFSLSVLPILY----KAGSSPSHHWQLQQKLEVLLGQVGKVCHQDIQ-----
-------DFTQATLDTTRSLCPRMLQGPGWREQLEGVLAGSSGL-----PELLPEQLLQD
TFSRLRDMRLSVT--ETLEESIVAQALAGLNAARDRLVES----------LAQQATVAMP
PTLSAL-DGGEPTPLGPGEL------EGL--FFPEKEEGVLLRKR--S------RSPWRL
QGKM--RS-----RRRNCLEQ--------R-----------------------GWQV---
---------------------------GPCDPGGRV-----------GA-----------
------------------------------------------------------------
--------------SVLVTVWLTERERGLRERAQCRVGEGVEEFFSKRLIHQDRLWAP--
EEDPAT-EGGTTPVPRTLRKKLGTLFAFKKPRSARGPRPDLETSPG-AAPRSRKATLGDL
LRPPARPGRGEEP------------GGAEV-GTSSPDPARRSRPRYTRDSKAYSMILLPA
EEE--EAALGDRPDKRRP---LERRDTEMAPSFEQRVQVILQRIGVSRGSGGAEGKRKQS
KDGEIKKAGSDGDIMDSSTEAPPISIKSRTHSVSADPSCRPGP---GGQGPEPTSWKTLG
QQLNAEMRGRGWGQQDGPGPP-------SP---CPS------SSPRRASPSPDSLGLPED
PCLGLRNE----------------------------ERP----L----RLQRSPVLKRRP
KLEAPL-PPS-LGPGPGAEPLPPQPTEPS--S-P------EQSLPSPAIDQ-----RGGG
PN---P-----------

------------------------------------------------------------
--------------------------------LTPWRAFLLY-LEHPLRVQTTFSYLEIS
DIDIQDPS-LVSFCLS--RI-HIKKFMSSEDLEQVIFHVATSIKKVFPDSSPGKLIRMT-
CADHEEKYKRIEDSLENITQNNQGPCGGFSQTYAALCDYNGFVLREEVQWDVDNIYHRQN
IREFNILDFSHLDT----TDIALTVASLSFNQWFTKIHCRDFKLRLEISEQILYVINRSL
KLEEIVLENCGLKC--------------EFAIKMAKALDNNPGSVLHTFNLSGNNIDDRG
V-------------NSLFQSF---------------------------------------
----------------VSHE-TFANSICHLDLSGNPGILATEDAI-SFYNFLD----NCK
SLCHLNLAGTDCALDS--------------------------------------------
LFGPLLHGSCSRLSYLNVSRNVYTHNKRKIK---DIPPEVSQFFSKTLALKHLNLS---G
TKIPSEMLREILHGLSTNDKIRNLHMDLSDCELRSSGAQVIQDMIFDINSLSSLDLSNNG
FDSDMVTLILSVGRSKSIKHVSLGKNFNIKSGTAVADIIHRIVQLIQDEDCTIESLSLAD
SRLKSEINILLNALGKKN-

PF00560 // ENSGT00390000014487_1_Domain_3 (740, 766)

NLRKIDISGNGMGDSGAKHLAKALQLNTQLRMI---TWDKN
NTTANGFLTLG---HALERN-YTLRFMPLPLSDISQAYRMNQSKTEDALHLLSAFLNNNN
IQC-TYQLCNKNAS-----SINSIEIFKEA-----------NKTPGTAR-----------
--KSNKNMGLGAGTPGSLNLSNKQAALRNMRSGKRSN-------GIVVETTREHP-----
-------KIWQMYEELGSQ----ME------------YEEEIIVQ---------------
AIDKIKNVNN--------------------------LIQSTKVISPQLLF----KWMKSV
NDIGKM-EEI--------------------SYIL--WN-----DSK-----SYWSIWLSW
INFLGEQNLK-----QKCTKKFVQKRKK----------------VER-----------ES
ERAPETQAQ-AV---------------QLSPL----------QKTSSGLKCIFWLPWQQD
VTKEGILLNPKNSTCTYCYR-GTPRPENFGVLHML---RSV------HWSFLSDLTCLSG
-INGMLRF----CALWTPEK---EKTEVNEKEVFAKLDEGLDDFFTKKLIQDYHEYPLQV
SSEPS---SLSSSGSRTFKKKIGDFFALRKPRNSKGSKPEKEQDGTPVTEKGRKPTLSDI
LRPLNKSVDSNKEKT---EDATSAEVGSVVDPAWTPDAARKIKPRCSREGKSQSLILLS-
EDE---EPFRIKQEKKRH---CEKLDGEACHTFEHRVHNMLHRIGVTRVLS-SEIKKKQN
KDGDIKKAGSEGDIVDSSAESPPPSLKARTHSMSTAERSTPKPEMVRNPADQSMIWKDIG
KQFKAELKGR--------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------

------------------------------------------MAQ-TPDGISCELRGEIT
RFLWPKEVELLLKTWLPG-EGA---VQNHVLALLRWRAYLLHTTCLPLRVDCTFSYLEVQ
AMALQETPPQVTFEL-ESLRELVLEFPGVAALEQLAQHVAAAIKKVFPRSTLGKLFRRPT
PASMLARLE-RSSASEST--DPCSPCGGFLETYEALCDYNGFPFREEIQWDVDTIYHRQG
CRHFSLGDFSHLGS----RDLALSVAALSYNLWFRCLSCVDMKLSLEVSEQILHMMSQSL
HLEELVLETCSLRG--------------DFVRRLAQALAGHS

PF13516 // ENSGT00390000014487_1_Domain_0 (343, 378)

SSGLRELSLAGNLLDDRG
M-------------TALSRHLERCPGALRRLSLAQTGLTPR-------------------
-------GMRALGRALATNA-AFDSTLTHLDLSGNPGALGASEDSGGLYSFLS----RPN
VLSFLNLAGTDTALDTVRGCSVGGWMTG------RADWRAGRGGL-G-PPAGVANSLPPQ
LFAALSRGCCTSLTHLDASRNVFSRTKSRAA-----PAALQLFLSRARTLRHLGLA---G
CKLPPDALRALLDGLALNTHLRDLHLDLSACELRSAGAQVIQDLVCDAGAVSSLDLADNG
FGSDMVTLVLAIGRSRSLRHVALGRNFNVRCKETLDDVLHRIVQLMQDDDCPLQSLSVAE
SRLKLGASVLLRALA

PF13516 // ENSGT00390000014487_1_Domain_3 (736, 760)

TNP-NLTALDISGNAMGDAGAKLL

ENSGT00390000014487_1_Linker_3_4 (760, 977)

AKALRVNSRLRSV---VWDRN
HTSALGLLDV---AQALEQN-HSLKAMPLPLNDVAQAQRSRPELTARAVHQIQACLLRNN
RADPASSDHTTRLQPLGLVSDPSEQEVNELCQSVQEHVELLGCGAGPQGEAAVRQA----
-EDAIQNANFSLSILPILY----EAGSSPSHHWQLGQKLEGLLRQVGEVCRQDIQ-----
-------DFTQATLDT

PF16000 // ENSGT00390000014487_1_Domain_4 (977, 1136)

ARSLCPQMLQGSSWREQLEGVLAGSRGL-----PELLPEQLLQD
AFTRLRDMRLSIT--GTLAESIVAQALAGLSAARDRLVES----------LAQQATVTMP
PALPAP-DGGEPSLLEPGEL------EGL--FFPEEK-E-E-------EKEKDDSPPQKW
PEL------------SHGLHLVPFIH----------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------VPPALPQE----GNGLSARVDEGVEEFFSKRLIQQDRLWAP--
EEDPAT-EGGATPVPRTLRKKLGTLFAFKKPRSTRGPRTDLETSPG-AAPRTRKTTFGDL
LRPPTRPSRGEEP------------GGAEG-DTSSPDPARRSRPRYTRDSKAYSMILLPA
EEE---AMLGARPDKRRP---LERGETELAPSFEQRVQVMLQRIGVSRGSGGAEGKRKQS
KDGEIKKAGSDGDIMDSSTEVPPISIKSRTHSVSADPSCRPGP---GSQGPESATWKTMG
QQLNAELRSHGWGQQDGPGPP-------SP---GQS------PSPCRTSPSPDSLGLPED
PCLGPRNEDGQL-RPRPLSAGRRAVSVHEDQLQAPAERP----L----RLQRSPVLKRRP
KLEAPP-SPS-LGSGLGTEPLPPQPTEPS--S-P------ERSPPSPATDQ-----RGGG
PN---P-----------

------------------------------------------MAQTPD-GISCELRGEIT
RFLWPKEAELLLKTWLPEREGA---ERGHVLALLRWRAYLLH-TCLPLRVDCTFSYLEVQ
AMALQETPPQVTFEL-ESLPELVLEFAGVAALEQLAQHIAAAIKKVFPRSNLGKLFRKPT
SSSMLARLE-RSSPSEDT--LPSSPCGGFLETYEALCDYNGFPFREEIQWDVDTIYHRQG
CRHFSLGDFSHLGS----RDLALSVAALSYNLWFQCLSCVDMKLSLEVSEQILHMMSQSS
HLEELVLENCGLRG--------------DFVRRLAQALAGHSSSA

PF13516 // ENSGT00390000014487_1_Domain_0 (346, 378)

LRELSLAGNLLDDRG
M-------------AALSRHLEYRPGALRKLSLAQTGLTAR-------------------
-------GMRSLGRALASNV-AFDSALTHLDLSGNPGALGSSEDSGGLYSFLS----RPN
VLMFLNLAGTDTALDTVRGWAGDRA----------RDLRVD-P-RGAQSIAGVAYTLFPQ
LFAALAGGCCASLSHLDASRNVFSRTKSRAA-----PDALQLFLSRAETLRHLGLA---G
CKLPPDALRALLEGLALNTHTGDLHLDLSACELRSAGAQVIQDLVCDAGAVSSLDLADNG
FGSDMVTLVLAIGRSRSLRHVALGRNFNVRCKETLDDVLHRIVQLMQDDDCPLQSLSVAE
SRLKLASSVLLRALG

PF13516 // ENSGT00390000014487_1_Domain_3 (736, 760)

TNP-NLTALDISGNAMGDTGAKML

ENSGT00390000014487_1_Linker_3_4 (760, 977)

AKALRVNTRLRSV---VWDRN
HTSALGLLDVA---QALEQN-RSLKAMPLPLNDVAQAHRSRPEMTTRAVHQIQACLLRNN
RADHASSDRTSCPQPPGLVSDPSEQEVNELCQSVQEHVELLGCGAGPQGEAAVHQA----
-EDAIQNANFSLSILPILY----EAGSSPSHQWQLRQKLEGLLGQVGEVCRKDIQ-----
-------DFTQATLDT

PF16000 // ENSGT00390000014487_1_Domain_4 (977, 1415)

TRSLCPQMLQGPRWREQLEGVLVGSRGL-----PELLPEHLLQD
AFTRLRDMRLSVT--GTLAESIVAQALEGLNAARDRLVES----------LAQQATVTMP
PAIPAL-DGGEPSPLGPGEL------EGL--FFSEEVREKQKDEEEQKHD----SPPQKW
PDS------------SQCFHLVLSTHSAAEEP---EPELAAPGE-DAEPQAGPS------
---ARGSPSPATPGPQA------------------------------G--PLPCM----D
LPPSGE--------PLRHPTRARPRPR-RQYHH---------------------------
------RPP---PGGPQVLPALPQE----GNGLSARVDEGVEEFFSKRLIQQDSLWVP--
EEDSAN-EGGTTPVPRTLRKKLGTLFAFKKPRSTRGSRPDLETSPG-AAPRTRKTTLGDL
LRPPSRPGRGEEP------------GGAEG-GTSSPDPAHRSRPRYTRESKAYSMILLPA
EE---EETLGTRPDKRRP---LERGDTELAPSFEQRVQVMLQRIGVSRSSGSAEGKRKQS
KDGEIKKAGSDGDIMDSSTEAPPISIKSRTHSVSADPSCRPGP---GSQGPESTTWKTLG
QQLNAELRGRGWGQQDGPGPP-------SP---CPS------PSPRRTSPSPDSLVLPED
PCLGPRNEDGQL-RPRPLSAGRRAVSVHEDQLQTPAERP----L----RLQRSPVLKRRP
KPEAPS-SPG-LGSGLGAQPLPPQPTEPS--S-P------EQKPPSPATDQ-----RGGG
PN---P-----------

------------------------------------------MA-QTPDGISCELRGEIT
RFLWPKEVELLLKTWLPG-EGA---VQNHVLALLRWRAYLLHTTCLPLRVDCTFSYLEVQ
AMALQETPPQVTFEL-ESLRELVLEFPGVAALEQLAQHVAAAIKKVFPRSTLGKLFRRPT
PAPMLARLE-RSSPLEST--GPCSPCGGFLETYEALCDYNGFPFREEIQWDVDTIYHRQG
CRHFSLGDFSHLGS----RDLALSVAALSYNLWFRCLSCVDMKLSLEVSEQILHMMSQSS
HLEELVLETCGLRG--------------DFVRRLAQALAGHS

PF13516 // ENSGT00390000014487_1_Domain_0 (343, 378)

SSGLRELSLAGNLLDDRG
M-------------AALSRHLERCPGALRRLSLAQTGLTPR-------------------
-------GMRALGRALATNA-AFDSALTHLDLSGNPGALGSSEDSGGLYSFLS----RPN
VLSFLNLAGTDTALDTVRGCSVGGWMID------RADWRAGQGGL-G-PPAGAANSLPPQ
LFAALSRGCCTSLTHLDASRNIFSRTKSRTA-----PAALQLFLSRARTLRHLGLA---G
CKLPPDALRALLDGLALNTHLRDLHLDLSTCELRSAGAQVIQDLVCDAGAVSSLDLADNG
FGSDMVTLVLAIGRSRSLRHVALGRNFNVRCKETLDDVLHRIVQLMQDDDCPLQSLSVAE
SRLKLGASVLLRALA

PF13516 // ENSGT00390000014487_1_Domain_3 (736, 760)

TNP-NLTALDISGNAMGDAGAKLL

ENSGT00390000014487_1_Linker_3_4 (760, 977)

AKALRVNSRLRWAGSEGWDQR
AGG-AGLNEAEQMESVVWDR-NHTSAMPLPLNDVAQAQRSRPELTARAVHQIQACLLRNN
RADPASSEHTTCLQLLGLVSDPSEQEVNELCQSVQEHVELLGCGSGPQGEAAVRQA----
-EDAIQNANFSLSILPILY----EAGSSPSHHWQLGQKLEGLLGQVGEVCRQDIQ-----
-------DFTQATLDT

PF16000 // ENSGT00390000014487_1_Domain_4 (977, 1139)

ARSLCPQMLQGSSWREQLEGVLAGSRGL-----PELLPEQLLQD
AFTRLRDMRLSIT--GTLAESIVAQALAGLSAARDRLVRGRCAHTFVTNGIMAEATVTMP
PALPAP-DGGEPSLLEPGEL------EGL--FFPQEEKEE--------EEEKDDSPPQKW
PEL------------SHGLHLVPFIQSKSG-----------------------PWGREFT
WVALSG--Y---------------P-------PALDWARP---GPPCAXX---------X
XXXX-X--------XXHPTR-ARPRPR-RQHHH---------------------------
------RPP---PGGPQVPPALPQE----GNGLSARVDEGVEEFFSKRLIQQDRLWAP--
EEDPAT-EGGATPVPRTLRKKLGTLFAFKKPRSTRGPRPDLETSPG-AAPRTRKTTFGDL
LRPPTRPSRGEEP------------GGAEG-DTSSPDPARRSRPRYTRDSKAYSMILLPA
EEE---ATLGARPDKRRP---LERGETELAPSFEQRVQVMLQRIGVSRGSGGAEGKRKQV
KGR----WHAVGDIMDSSTEAPPISIKSRTHSVSADPSCRPCP---GSQGPESATWKTLG
QQLNAELRSRGWGQQDGPGPP-------SP---GQS------PSPCRTSPSRDSLGLPED
PCLGPRNEDGQL-RPRPLSAGRRAVSVHEDQLQAPAERP----L----RLQRSPVLKRRP
KLEAPP-SPS-LGSGLGTEHLPPQPTEPS--G-P------EQSPPSPATDQ-----RGGG
PS---P-----------

------------------------------------------MA-QTPDSISCELRGEIT
RFLWPKEAELLLKTWLPQ-EGS---ERSHILALLRWRAYLLH-TCLPLRVDCTFSYLEVQ
AMALQETPPQVTFEL-ESLPELVLEFPGVATVEQLAQHVASAIKKVFPRSTLGKLFRKPT
PTSMLARLE-RSNPSESM--APRSPCGGFLETYEALCDYNGFPFREEIQWEVDTIYHRQG
CRQFSLGDFSHLGS----RDLALSVAALSYNLWFRCLSCVDMKLSLEVSEQILHMMGQSS
HLEELVLETCGLRG--------------DFVRRLAQALAGHS

PF13516 // ENSGT00390000014487_1_Domain_0 (343, 378)

SSGLRELSLAGNLVDDRG
M-------------AALSRHLEHRPGALRRLNLAQTGLTPR-------------------
-------GMRALGQALATNA-AFDSALTHLDLSCNPGALGASEDNGGLYSFLS----RPN
ALMFLNLAGTDAALDT--------------------------------------------
LFTALSSGCCSSLTYLDTSRNVFSRCKSPAA-----AASLQLFLSRAETLRHLGLA---G
CKLPPEALRAVLDGLALNTHIRDLHLDLSACELRSAGAQVIQDLVCDAGVVSSLDLEDNG
FGSDMVTLVLAIGRSQSLRHVALGRNFNVRCKETLDDVLHRIVQLMQDDDCPLQSLSVAD
SRLKLGAGVLLRALS

PF13516 // ENSGT00390000014487_1_Domain_3 (736, 760)

TNP-NLTALDISGNAMGDTGAKML

ENSGT00390000014487_1_Linker_3_4 (760, 977)

AKALGVNTRLRSV---IWDRN
HTSALGLLDVA---QALEQN-HSLKDMPLPLNDVVQAQRSRPELTARAVHQIQACLLRNN
HEDPTSSGPSSCLQPLNLVSDHSEQEVNELCQSVQEHMELLGCGAGPQGEAAVHQA----
-EDAIQNANFFLSILPILN----EAGNSPSYQWQLRQKVEALLEQVGEVCRQDTQ-----
-------DFIQAILDT

PF16000 // ENSGT00390000014487_1_Domain_4 (977, 1415)

TRSLCRQMLQGPGWREQLEGVLVGSEGL-----PELLPEQLLQD
VFTRLRDIRLSVT--GTLSENIVAQALAGLSAAQDRLVES----------LAQQAPVAMP
PSLPAL-DGGELSPLGPGAL------EGF--FFPEDKEEEE---------EKDESPLWKW
PE--------------HCLHLVPFDYSAAE-----------------------QAEPEPE
LAAPGEDAE---------------PQAGPSARGSPSPAAP---GPPGGPLPRMDL----P
PAGQ-P--------LRHPTR-ARPRPR-RQHHH---------------------------
------RPP---PGGPQVPPALPQE----GNGLSARVDEGVEEFFSKRLIQQDCLWAP--
E-EDPATEGGATPVPRTLRKKLGTLFAFKKPRSTRGPRPDLETSPG-AAARTRKTTLGDL
LRPPARPGRGEEP------------GGTEG-GPSSPDPARRSRPRYTRESKAYSMILLPA
E-E---ETLNARPDKRRP---LERGDTELTPSFEQRVQVMLQRIGVSRGSGGAEGKRKQS
KDGEIKKAGSDGDIMDSSTETPPISIKSRTHSVSADPSCRPGP---GVQGPESATWKTLG
QQLNAELRGRGWGQQDGPGPP------SSP---CPS------PNFRRASPAPDSLGLPED
PCLGPRNEDGQL-RPRPLSAGRRAVSVHEDQLQGPAERP----L----RLQRSPVLKRRP
KLEAPP-SPS-LGSGLGTEPLPPQPTEPS--S-P------EQSPPSPATDQ-----RGGG
PN---L-----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MPLPLNDVTQAHRSRPELTTRAVHQIQACLWRNN
QADS-TSDLKPRLQPLGLISDHSEQEVNELCQSVQEHMELLGCGAGPQGEVAVHQA----
-EDAIQNANFSLSILPILY----EAGRSPSHHWQLQQKLESLLGQVGEICRQDIQ-----
-------DFTQTTLDT

PF16000 // ENSGT00390000014487_1_Domain_4 (977, 1415)

TRSLCPQMLQTPGWRKQLEGVLVGSGGL-----PELLPEHLLQD
AFARLRDMRLSIT--GTLAESIVAQALAGLHAARDRLVES----------LTQQAPVTVA
PAVPPL-GGNELSPFETGGL------EEL--FFPTEKEEEREQD---------DGSSWKW
LEP------------SNCFHLVSSL-----------------------PGAAEEAERDPE
LAAPGEDAEPQA---------------GPSARGSPSPAAP---GPPAGPLPRMDL----P
PAGQ-P--------LRH-PTRARPRPR-RQHHH---------------------------
------RPP---PGGPQVPPALLQE----GNGLTARVDEGVEEFFSKRLIQQDHLWAP--
EEDPAA-EGGTTPVPRTLRKKLGTLFAFKKPRSTRGPRPDLETSPG-AAARARKTTLGDL
LRPPARPGRG-EEP-----------GGAEG-GTSSPDPARRNRPRYTRESKAYSMILLPA
EE---EAAVGTRPDKRRP---LERGDTELAPSFEQRVQVMLQRIGVSRGSAGAESKRKQS
KDGEIKKAGSDGDIMDSSTETPPISIKSRTHSVSADPSCRPGP---GGQGPESATWKTLG
QQLNAELRGRGWGQQDGPGPP-------SP---CPS------PSPRRTSPAPDILSLPED
PCLGPRNE----------------------------ERP----L----RLQRSPVLKRRP
KLEAPP-SPS-LGSDLGSKPLPPYPTEPS--S-P------ERSPPPPATDQ-----RGGG
PN----P----------

------------------------------------------MAQTPD-GISCELKGEIT
RFLWPKEAELLLKTWLPEREGA---ERGHVLALLRWRAYLLH-TCLPLRVDCTFSYLEVQ
AMALQETPPQVTFEL-ESLPELVLEFPGVAALEQLAQHIAAAIKKVFPRSSLGKLFRRPT
SPTMLARLE-RSSPSEDS--APSSPCGGFLETYEALCDYNGFPFREEIQWDVDTIYHRQG
CRHFSLCDFSHLGS----RDLALSVAALSYNLWFQCLSCVDMKLSLEVSEQILHMMSQSS
HLEELVLENCGLRG--------------DFVRRLAQALAGHSSS

PF00560 // ENSGT00390000014487_1_Domain_0 (345, 384)

ALRELSLTGNLLDDRG
M-------------TALSRHLEHCPGALRRLSLAQTGLTPR-------------------
-------GMRSLGRALASNV-AFDTVLTHLDLSGNPGALGASEDNGGLYSFLS----RPN
VLTFLNLAGTDTALDTVRGWSAGRA------GGRAQGLRVDRG-RGARSSVGVARTFLPQ
LFAALARGCCTCLSHLDASRNVFSRTKSRAA-----PAALQLFLSRAGTLRHLGLA---G
CKLPPDALRALLEGLALNTHTGDLHLDLSACELRSAGAQVIQDLVCDAGAVSSLDLADNG
FGSDMVTLVLAIGRSRSLRHVALGRNFNVRCKETLDDVLHRIVQLMQDDDCPLQSLSVAE
SRLKLASSVLLRALGTNP-NLTALDISGNAMGDTGAKMLAKALRVNTRLRSV---VWDRN
HTSALGLLDVA---EALEQN-RSLRAMPLPLNDVAQAHRSRPELTARAVHQIQACLLRNN
HADHDSSDRTSCPQPPGLVSDPSEQEVNELCQSVQEHVELLGCGAGPQGEAAVHQA----
-EDAIQNANFSLSILPILY----EAGSSPSHQWQLRQKLEGLLRQVGEVCRKDIQ-----
-------DFTQATLDTTRSLCPQMLQGPRWREQLEGVLVGSRGL-----PELLPEHLLQD
AFTRLRDMRLSVT--GTLAESIVAQALEGLNAARDRLVES----------LAQQATVAMP
LAIPAL-DGGEPSPLGPGEL------EGL--FFPEEVKEKEEDE-EEKDD----SPPQKW
PES------------SQCLYLVPSTHSKSGSGGKPEARLEQTRIRTLSPFASPTPFPTPR
MRMLGGSAEPRRSGPRS------------------------------A--PRTAV-----
-----A--------GGRGRGRARPRPR-RQHHH---------------------------
------RPP---PGGPQVPPALPQE----GNGLSARVDEGVEEFFSKRLIQHDRLWVP--
EEDPAN-EGGATPVPRTLRKKLGTLFAFKKPRSTRGPRPDLETSPG-AAPRTRKTTLGDL
LRPPARPGRGEEP------------GGAEG-GTSSPDPARRSRPRYTRESKAYSMILLPA
EEE-GEESLGARPDKRRP---LERGDTELAPSFEQRVQVMLQRIGVSRGSGSAEGKRKQS
KDGEIKKAGSDGDIMDSSAEAPPISIKSRTHSVSADPSCRPGP---GSQGPESTSWKTLG
QQLNAELRGRGWGQQDGPGPP-------SP---CPS------PSPRRASPSPDSLGLPED
PCLGPRNEDGQL-RPRPLSAGRRAVSVHEDQLQAPVERP----L----RLQRSPVLKRRP
KLEAPS-SPG-LGSGLGAQPLPPQPTELS--S-P------EPNPPSPATDQ-----RGGG
PN---P-----------

------------------------------------------MAQ-TPDGISCELRGEIS
RFLWPKEAELLLKTWLPQ-EGA---ERSHVLALLRWRAYLLH-TCLPLRVNCTFSYLEVQ
AMGLQETPPQVTFEL-ESLPELVLEFPGVAPLEQLARHVAAAIKKVFPRSTLGKLFRRPT
PPSMLARLE-RSSLSGST--APCSPCGGFLETYEALCDYNGFPFREEIQWDVNTIYHHQG
CRHFSLGDFSHLGS----RDLALSVAALSYNLWFRCLSCVDMKLSLEVSEQILHMMSQSS
HLEELVLETCGLRG--------------DFVRRLAQVLAGHA

PF13516 // ENSGT00390000014487_1_Domain_0 (343, 378)

NSGLRELSLAGNLLDDRG
M-------------AALSRHLEHRPGALRRLSLAQTGLTPR-------------------
-------GMRSLGRALATNT-AFHSALTHLDLSGNPGALGASEDSGGLYSFLS----RPN
VLNFLSLAGTDTALDTVRGCSGRGG---------GEEWAR--------PPRRFEER----
LFPHVGRTCP-GLGE---AAGSRLLAKSRAA-----PAALQLFLSHAGTLRHLGLA---G
CRLPPVALRALLDGLALNTHLRDLHLDLSACELRSAGAQVIQDLVCDAGAVSSLDLADNG
FGSDMVTLVLAIGRSRSLKHVALGRNFNVRCKETLDDVLHRIVQLMQDDDCPLLSLSVAE
SRLKLGASVLLRALG

PF13516 // ENSGT00390000014487_1_Domain_3 (736, 760)

TNP-NLTALDISGNAMGDAGAKLL

ENSGT00390000014487_1_Linker_3_4 (760, 978)

AKALRVNSRLRSV---VWDRN
HTSALGLLDVA---QALEQN-HSLKAMPLPLSDVAQAQRSRPELTARAVHQIQACLLRNN
RADSASSDPKSRLQPLGLVSDPSEQEVNELCQSVQEHVELLGCGAGPQGEATVHQA----
-EDAIQNANFSLSILPILY----EAGSSPSHHWQLQQKLEGLLGQVGEVCCQDIQ-----
-------DFTQATLDTT

PF16000 // ENSGT00390000014487_1_Domain_4 (978, 1132)

RRLFSKMLQGSSWREQLEGVLVGSRGL-----SELLPEQLLQD
AFTRLRDMRLSIM--RTLADSIVSQALEGLSAARDQLVES----------LAQQATVAVP
TTLPAL-DGGEPSPLGPGQL------EGL--FFPKEEEEE--EKK--EKEEKDDNPPWKW
PEP------------NHGLHLSIR--SKSG-----------------------TWG----
------------------------------------------------------------
----------------------------KGHHH---------------------------
------RPP---PGGPQVPPALPQE----GNGLSARVDEGVEEFFSKRLIQQDRLWAP--
EEDPAT-EGGAAPVPRTLRKKLGTLFAFKKPRSTRGPRPDLETSPG-AAPRTRKTTLGDL
LRPPTRPSRGEEP------------GGAEG-GTSSPDPSRRNRPRYTRDSKAYSMILLPA
EEE--EATLGARPDKRRP---LERGDTELAPSFEQRVQVMLQRIGVSRGSGGAEGKRKQS
KDGEIKKAGSDGDIMDSSTEAPPISIKSRTHSVSADPSCRPGP---GSQGPESATWKTLG
QQLNAELRGRGWGQQDGPGPP-------TP---CQS------PSPRRASPSPDSLGLPED
PYLGPRNEDGQL-RPRPLSAGRRAVSVHEDQLQAPAERP----L----RLQRSPVLKRRP
KLEAPP-SPS-LGSGLGTEPLPPQPTEPP--S-P------EQSPPSPATDQ-----RGGG
PN---P-----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MPLPLNDVTQAHRSRPELTTRAVHQIQACLWRNN
QADS-TSDLKPCLQPLGLISDHSEQEXNELCQSVQEHVELLGCGAGPQGEVAVHQA----
-EDAIQNANLSLSILPILY----EAGRSPSHHWQLQQKLESLLGQVGEICRQDIQ-----
-------DFTQTTLDT

PF16000 // ENSGT00390000014487_1_Domain_4 (977, 1415)

ARSLCPQMLQTPDWRKQLEGVLVGSGGL-----PELLPEHLLQD
AFSRLRDMRLSIT--GTLAESIVAQALAGLHAARDRLVES----------LTQQAPVTMT
PAVPPL-GGNELSPLETGGL------EEL--FFPTEKEEEKEKD---------NSSSWKW
LEP------------SNCFHLVSSLHGKSGLV------------SSL-HGAAEEAERDPE
LAAPGEDAEPQA---------------GPSARGSPSPAAP---GPPAGPLPRMDL----P
PAGQ-P--------LRH-PTRARPRPR-RQHHH---------------------------
------RPP---PGGPQVPPALLQE----GNGLTARVDEGVEEFFSKRLIQQDHFWAP--
EEDPAT-EGGATPVPRTLRKKLGTLFAFKKPRSTRGPRPDLETSPG-AAARARKSTLGDL
LRPPARPGRG-EEP-----------GGAEG-GTSSPDPARRNRPRYTRESKAYSMILLPA
EE---EAAVGTRPDKRRP---LERGDTELAPSFEQRVQVMLQRIGVSRGSGGAESKRKQS
KDGEIKKAGSDGDIMDSSTETPPISIKSRTHSVSADPSCRPGP---GGQGPESATWKTLG
QQLNAELRGRGWGQQDGPGPP-------SP---CPS------PSPRRTSPAPDILSLPED
PCLGPRNE----------------------------ERP----L----RLQRSPVLKRRP
KLEAPP-SPS-LGSGLGSKPLSPYPTEPS--S-P------ERSPPSPATDQ-----RGGG
PN----P----------

------------------------------------------MA-QNPDEISSELRGEIT
RFLWPKEVELLLKTWLPQ-QGA---EQSHVLALLRWRAYLLH-TCLPLRVDCTFSYLEVQ
AMVLQETPPQVTFEL-ESLPDLVLEFPGVAAVEQLAQHVAAAIKKAFPHSTLGKLFRKPT
PPSMLARLE-RSNSSELT--APSSPCGGFLKTYEALCDYNGFPFQEEIQWDIDTIYHRQG
CRHFCLGDFSHLSS----RDLALSVAALSYNRWFRRLSCVDMKLSLEVSEQILHMMSQSS
HLEELVLETCGLRG--------------DFVRRLAQILTRH

PF13516 // ENSGT00390000014487_1_Domain_0 (342, 377)

SNSGLRELSLAGNLLDDRG
I-------------IRLSLGIEKGVCRI------------------------------IE
TRPRPPPGMRALGQALATNA-AFDSTLTHLDISGNPGALGASEDSGGLYSFLS----HPN
VLAFLNLAGTDTALDMVRSWSRVGNRKG------GAGK----------------------
VLGRMLRKACASI-----LPPAFHPRKSWAQ-----PAALKLFLSQAGMLRHLSLA---G
CKLPSDALRALLDGLALNTHICNLHLDLSACELRSAGAQVIQDLVCDAGAVSSLDLADNG
FGSDMVTLVLAIGRSRSLKHVALGRNFNVRCKETLDDVLHRIVQLMQDDDCPLQSLSVAE
SRLKLGASVLLQALG

PF13516 // ENSGT00390000014487_1_Domain_3 (736, 760)

TNP-NLTALDISGNAMGDAGAKML

ENSGT00390000014487_1_Linker_3_4 (760, 978)

AKALRVNTRLRSV---IWDRN
HTSAVGLLDVA---QALEQN-HSLKSMPLPLMDVTQAQRSRPELTARAVNQIQACLLRNN
RTDPVSSNRTSHLEPLGLVSDRLEQEVNELCQSVQEHVELLGCGAGPQGEAAVRQA----
-EDAIQNANFSLSILPILY----EAGSSPSHHWQLQQKLDSLLEQVGEICCQDIQ-----
-------NFTQATLDTT

PF16000 // ENSGT00390000014487_1_Domain_4 (978, 1415)

KSLCSRMLQEPGWREQLEKVLVASSGL-----PELLPEQLLQD
AFTRLKDMRLSIT--GTLAESIVAQALVGLSAARDQLVES----------LAKQAPVTMP
PTQPAV-S-GELSPFGPGEL------EGL--FFLEKKEEEE---------RKDDSPSGKR
PEA------------SHCLHLVPFLHSKSG-----------------------PLGKAPL
DLGTVRHS-------------FGLSR----------------------VLPKL-------
--------------LRGPGR-ARPDA-TGKHHH---------------------------
------RPP---PGGPQVPPALPQE----GNGLSARVDEGVEEFFSKRLIQQDSLWAP--
EEDPAT-EGGATPVPRTLRKKLGTLFAFKKPRSTRGPRPDLETSPG-AAARARKTTLGDL
LRPPPRPGRGDES------------GGAEG-GTSSPDPARRSRPRYTRESKAYSMILLPA
EEE--AATLGARPDRRRP---LERGDTELAPSFEQRVQVMLQRIGVSRGSGGTEGKRKQV
SWGVSVK--RGGDIMDSSTETPPISIKSRTHSVSADSSCRPGP---GGHGPESTTWKTLG
QQLNAELRGRGWGQQDGPGPP-------SP---CPS------PSPRRGSPSPDILGLPED
PCLGSRNEEYGK-----------ACAHSQQPFLCPSERP----L----RLQRSPVLKRRP
KLEAPP-SPS-LGSGLGTEPLLPQPTEPS--S-P------ERSPPSPATDQ-----RGGG
PN---P-----------

------------------------------------------MAQ-TPDGISCELRGEIT
RFLWPKEVELLLKTWLPG-EGA---VQNHVLALLRWRAYLLHTTGLPLRVDCTFSYLEVQ
AMALQETPPQVTFEL-ESLRELVLEFPGVAALEQLAQHVAAAIKKVFPRSTLGKLFRRPT
PASMLARLE-RSSPLEST--GPCSPCGGFLETYEALCDYNGFPFREEIQWDVDTIYHRQG
CRHFSLGDFSHLGS----RDLALSVAALSYNLWFRCLSCVDMKLSLEVSEQILHMMSQSS
HLEELVLETCGLRG--------------DFVRRLAQALAGHS

PF13516 // ENSGT00390000014487_1_Domain_0 (343, 378)

SSGLRELSLAGNLLDDRG
M-------------AALSRHLERCPGALRRLSLAQTGLTPR-------------------
-------GMRALGRALATNA-AFDSALTHLDLSGNPGALGSSEDSGGLYSFLS----RPN
VLSFLNLAGTDTALDTVRGCSVGGWMTD------RADWRAGQGGL-G-PPAGAANSLPPQ
LFAALSRGCCTSLTHLDASRNVFSRTKSRAA-----PAALQLFLSRARTLRHLGLA---G
CKLPPDALRALLDGLALNTHLRDLHLDLSACELRSAGAQVIQDLVCDAGAVSSLDLADNG
FGSDMVTLVLAIGRSRSLRHVALGRNFNVRCKETLDDVLHRIVQLMQDDDCPLQSLSVAE
SRLKLGASVLLRALA

PF13516 // ENSGT00390000014487_1_Domain_3 (736, 760)

TNP-NLTALDISGNAMGDAGAKLL

ENSGT00390000014487_1_Linker_3_4 (760, 977)

AKALRVNSRLRSV---VWDRN
HTSALGLLDV---AQALEQN-HSLKAMPLPLNDVAQAQRSRPELTARAVHQIQACLLRNN
RADPASSDHTTCLQPLGLVSDPSEQEVNELCQSVQEHVELLGCGAGPQGEAAVRQA----
-EDAIQNANFSLSILPILY----EAGSSPSHHWQLGQKLEGLLGQVGEVCRQDIQ-----
-------DFTQATLDT

PF16000 // ENSGT00390000014487_1_Domain_4 (977, 1415)

ARSLCPQMLQGSSWREQLEGVLAGSRGL-----PELLPEQLLQD
AFTRLRDMRLSIT--GTLAESIVAQALAGLSAARDQLVES----------LAHQATVTMP
SALPAP-DGGEPGLLEPGEL------GGL--FFPEEEKE-E-------EEEKDDSPPQKW
PEL------------SHGLHLVPFIQSAAE-----------------------EAEPEPE
LAAPGEDAE---------------PQAGPSARGSPSPAAP---GPPAAPLPRMDL----P
PAGQ-P--------LRHPTR-ARPRPR-RQHHH---------------------------
------RPP---PGGPQVPPALPQE----GNGLSARVDEGVEEFFSKRLIQQDRLWAP--
EEDPAT-EGGATPVPRTLRKKLGTLFAFKKPRSTRGPRPDLETSPG-AAPRTRKTTFGDL
LRPPTRPTRGEEP------------GGAEG-DTSSPDPARRSRPRYTRDSKAYSMILLPA
EEE---ATLGARPDKRRP---LERGETELAPSFEQRVQVMLQRIGVSRGSGGAEGKRKQS
KDGEIKKAGSDGDIMDSSTEAPPISIKSRTHSVSADPSCRPCP---GSQGPESATWKTLG
QQLNAELRSRGWGQQDGPGPP-------SP---GQS------PSPCRTSPSRDSLGLPED
PCLGPRNEDGQL-RPRPLSAGRRAVSVHEDQLQAPAERP----L----RLQRSPVLKRRP
KLEAPP-SPS-LGSGLGMEHLPPQPTEPS--S-P------ERSPPSPATDQ-----RGGG
PS---P-----------

------------------------------------------MAQ-NPDGISCELRGEIT
RFLWPKEVELLLKTWLPG-EGA---VQNHVLALLRWRAYLLHTTCLPLRVDCTFSYLEVQ
AMALQETPPQVTFEL-ESLRELVLEFPGVAALEQLAQHVAVAIKKVFPCSTLGKLFRRPT
PASMLARLE-RSSPLEST--DTCSPCGGFLETYEALCDYNGFPFREEIQWDVDTIYHRQG
CRHFSLGDFSHLSS----RDLALSVAALSYNLWFRCLSCVDMKLSLEVSEQILHMMSQSS
HLEELVLETCGLRG--------------DFVRRLAQVLAGHS

PF13516 // ENSGT00390000014487_1_Domain_0 (343, 378)

SSGLRELSLAGNLLDDRG
M-------------AALSRYLERCPGALRRLNLAQTGLTPR-------------------
-------GMRALGQALATNA-AFDSILTHLDLSGNPGVLGPSEDSGGLYTFLS----RPN
ALSFLNLAGTDTALDI--------------------------------------------
LFTALSRGCCASLTHLDASRNVFSRTKSHAP-----PAALQLFLSRSGTLRHLGLA---G
CKLPPDALRALLDGLALNTHLRDLHLDLSACELRSAGAQVIQDLVCDAGAVSSLDLADNG
FGSDMVTLVLAIGRSRSLRHVALGRNFNVRCKETLDDVLHRIVQLMQDDDCPLQSLSVAE
SRLKLGASVLLRALA

PF13516 // ENSGT00390000014487_1_Domain_3 (736, 760)

TNP-NLTALDISGNAVGDAGAKLL

ENSGT00390000014487_1_Linker_3_4 (760, 977)

AKALRVNSRLRSV---VWDRN
HTSALGLLDVA---QALEQN-HTLKAMPLPLNDLAQAQRSRPELTARAVHQIQACLLRNN
RADPASSDHTTHLQPLSLVSDPSEQEVNELCQSVQEHVELLGCGAGPLGEAAVRQA----
-EDAIQNANFSLSILPILY----EAGSSPSYHWQLGQKLEDLLGHVGEVCRQDIQ-----
-------DFTQATLDT

PF16000 // ENSGT00390000014487_1_Domain_4 (977, 1415)

ARNLCPQMLQGSSWREHLEGVLAGSRGL-----PELLPEQLLQD
ALTRLRDIRLSIT--GTLAESIVAQALAGLSAARDRLVES----------LAQQAMVTMP
PSLPAL-NGGQPSPLEPGEL------EGL--FFSKEEKEEK-------EEEKDDSLARKW
PEF------------SHSLHLVPFIHSAAE-----------------------EAEPEPE
LAAPGEDAE---------------PQAGPSARGSPSPATP---GPPAGPLPRMDL----P
SAGQ-P--------LHHPTR-ARPRPR-RQHHH---------------------------
------RPP---PGGPQVPPALPQE----GNGLSARVDEGVEEFFSKRLIQQDRLWAL--
EEDPAT-EGGTTPVPRTLRKKLGTLFAFKKPRSTRGPRPDLETSPG-AAPRTRKTTFGDL
LRPPTRPSRGEEP------------GGAEG-DTSSPDPARRSRPRYTRDNKAYSMILLPA
EEE---AMLGARPDKRRP---LERGETELAPSFEQRVQVMLQRIGVSRGSGGAEGKRKQS
KDGEIKKAGSDGDIMDSSTEAPPISMKSRTHSVSADPSCRPGP---GSQGPESATWKTLG
QQLNAELRSRGWGQQDGPGPP-------SP---GQS------PSPCRASPSPDSLGLPED
PCLGPRNE----------------------------ERP----L----RLQRSPVLKRRP
KLEAPS-SLS-LGSGLGTEPLHPQPTEPS--S-P------ERSPPSPATDQ-----RGGG
PN---P-----------

------------------------------------------MAQTPD-DISCELRGEIT
RFLWPKEVEVLLKTWLPQ-EGA---ERSHILALLRWRAYLLH-TCLPLRVDCTFSYLEVQ
AMALQETPPQVTFEL-ESLPELVLEFPGIAALEQLAQHVAAAIKKVFPRSTLGKLFRNPT
PPSMLARLE-RSHPLEFT--APSNPCGGFLEAYEALCDYNGFPFREEIQWDVDTIYHRQG
SRHFCLGDFSHLGS----RDLALSVAALSYNLWFRCLSCVDMKLSLEVSEQILHMMSQSS
HLEELVLETCGLRG--------------DFVRRLAQALTGHS

PF13516 // ENSGT00390000014487_1_Domain_0 (343, 378)

SSGLRELSLAGNLLDDRG
M-------------VALSRHLEHRPGALRRLSLAQTGLTPR-------------------
-------GMRALGRALAANA-AFDSTLTHLDLSGNPGALGASEDNGGLYTFLN----RPN
VLAFLNLAGTDTALDTVRGAWEGG----------------------LGPQEHVVNFAFPQ
LFAALSGGCCASLTHLDASRNIFSRTKSRAA-----PAALQCFLSCAETLRHLGLE---G
CKLPPEALRALLDGLARNTHIRDLHLNLSACELRSAGAQVIQDLVCYAGALNSLDLADNG
FGSDMVTLVLAIGRSRSLKHVALGRNFNVRCKETLDDVLHRIVQLMQDDDCPLQSLSVAE
SRLKQGASVLLRALS

PF13516 // ENSGT00390000014487_1_Domain_3 (736, 760)

TNP-KLTALDISGNAMGDAGAKML

ENSGT00390000014487_1_Linker_3_4 (760, 977)

AKALRVNTRLRSV---TWDRN
NTSALGLLDVA---QALEQN-HSLKSMPLPLNDVTQAQRSRPELTAHAVHQIQACLLRNN
RTDPPSSDFESRLQSLGLISDCSEQEVNELCQSVQEHVELLGCGAGPQGEAAVHQA----
-EDAIQNANFSLSILPILY----EAGSSPSHQWQLQQKLEGLLGQVSEVCRQDIQ-----
-------DFTQTTLDT

PF16000 // ENSGT00390000014487_1_Domain_4 (977, 1415)

TRSLCPQMSKRPGWKEQLEEVLVGSRGL-----PELLSEQLLQD
AFSRLRDVRLSVT--GILAENIVAQALAGLNEARDRLVES----------LARRAPVTIP
LAVSSL-GGDEPSPLESGEL------EGL--FFSVEKEEEGEKD---------APSSQKW
P--------------SHCFHL----------F------------PSL-HGAAEEAEPEPE
LAAPGEDAEPQA---------------GPSARGSPSPAAP---GPPSGQLPRMDL----P
PAGQ-P--------LRH-PTRARPRPR-RQHHH---------------------------
------RPP---PGGPQVPPAQLQE----GNGLSARVDEGVEEFFSKRLIQQEQLWVP--
EEDPAT-EGGATPVPRTLRKKLGTLFAFKKPRSTRGPRPDLETSPG-TAVRARKNTLGDL
LRPPARPGRGGDEP-----------GGAEG-GTSSPDPARRSRPRYTRESKAYSMILLPA
EEE--EAALNARSDKRRP---LERGDTELAPSFEHRVQVMLQRIGVSRGSGGAENKRKQS
KDGEIKKAGSDGDIMDSSTETPPISIKSRTHSVSADPSCRPGP---GGQEPESATWKTLG
QQLNAELRGRGWGQQDGPGPP-------SP---CLS------PSPQRTSPSPDILSLPDD
PCLVPRNEDGQL-RPRPLSAGRRAVSVHEDQLQAPAGEG----DTSVLGKRGPGTLSTAQ
NLSFSP-SPL-TGSGLGTKPLPPYSTEPS--S-P------EQSPPSPATDQ-----RGGG
GP---KP----------

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--------------------------MPLPLNDVTQAHRSRPELTTRAVHQIQACLWRNN
QVDS-TSDLKPCLQPLGLISDHSEQEVNELCQSVQEHMELLGCGAGPQGEVAVHQA----
-EDAIQNANFSLSILPILY----EAGRSPSHHWQLQQKLESLLGQVGEICRQDIQ-----
-------DFTQTTLDT

PF16000 // ENSGT00390000014487_1_Domain_4 (977, 1415)

TRSLCPQMLQTPGWRKQLEGVLVGSGGL-----PELLPEHLLQD
AFSRLRDMRLSIT--GTLAESIVAQALAGLHAARDRLVER----------LTQQAPVTMA
PAVPPL-GGNELSPLETGGL------EEL--FFPTEKEEEREKD---------ESSSWKW
LEP------------SNCFHLVSSL-----------------------HGAAEEAERDPE
LAAPGEDAEPQA---------------GPSARGSPSPAAP---GPPAGPLPRMDL----P
PAGQ-P--------LRH-PTRARPRPR-RQHHH---------------------------
------RPP---PGGPQVPPALLQE----GNGLTARVDEGVEEFFSKRLIQQDHFWAP--
EEDPAT-EGGATPVPRTLRKKLGTLFAFKKPRSTRGPRPDLETSPG-AAARARKSTLGDL
LRPPARPGRG-EEP-----------GGAEG-GTSSPDPARRNRPRYTRESKAYSMILLPA
EE---EAAVGTRPDKRRP---LERGDTELAPSFEQRVQVMLQRIGVSRASGGAESKRKQS
KDGEIKKAGSDGDIMDSSTETPPISIKSRTHSVSADPSCRPGP---GGQGPESATWKTLG
QQLNAELRGRGWGQQDGPGPP-------SP---CPS------PSPRRTSPAPDILSLPED
PCLGPRNE----------------------------ERP----L----RLQRSPVLKRRP
KLEAPP-SPS-LGSGLGSKPLPPYPTEPS--S-P------ERSPPSPATDQ-----RGGG
PN----P----------

------------------------------------------MA-VSPGGIPAELQEGIA
ASLGAKQILLLKNVQLQV----KSKYDDFILVLTPWRAYVLL-AALPVRVHSSFSFLEVK
DITVLEPS-VVVIETD--TSSYAFRLMSFDDLEQVVVHVTMSLKKVFPDSSPGTLLKNS-
PPNLYERIRMVTDSMEEMLQSNQGPCGGFSETYAALCDYNGFTFREEIQWDVDNIYHGQD
CREFNLLDFSHLES----RDVALSVAALSFNLWFTKLSCKDFRLNQEIAEQLLYMLSKSV
KLEELVLENSGLRG--------------DFAQRMAQALSRHPESI

PF13516 // ENSGT00390000014487_1_Domain_0 (346, 378)

LHTINLAGNQLEDRG
I-------------IAFSRLFEERPKGLQSLILARTMLTAK-------------------
-------GMSALCQALAANE-AISSSLRHLDLSGNPGSLAVEDTS-SLQSLLG----RCS
SLTHLSLAATDCSLDT--------------------------------------------
LFGALVHGCCASLVHVDLSKNVYSHR--RVK---TISPSVKQFFSQARALRHISMA---G
TKLPPDAVRAVLQGLAYNSHISDLHLDLSSCELRSAGAQVIQDLIPDASAISDLDLSDNG
FDSDMVTLVLSIGRSKSIRHVSLGKNFNIKSKDGLVDVLHRIVQLTQEDDCPLQSLSVAE
SRLKLGTNVLLSALG

PF13516 // ENSGT00390000014487_1_Domain_3 (736, 760)

SNT-SLTTLDISGNAMGDTGAKML

ENSGT00390000014487_1_Linker_3_4 (760, 977)

AKALQINTKLRTV---VWDRN
NTTALGLLEVA---QALERN-YTLKSMPLPMSDVAQAYRSNPERTEEAVHKLQSCLARNQ
TRR-ALPTQTFRLQ-QGILTSSSEQMVNEICLSVQKHIDILSSCPGREMEADILRA----
-EEAIRNANLAVSILPMLY----EAGNAPHQSGKLQHKLECLVEEASQTCGREIQ-----
-------AIMQAVLDA

PF16000 // ENSGT00390000014487_1_Domain_4 (977, 1416)

AHNLCPPMVQKSGARDQLVNAMSERIHLQEHLSLSAVLDQMVTD
VFSKLNEIKLSIT--AAVADCIVDAVLGDLMAAQCKLAESLPTHGPDLLE--------PA
E----D-DAAAPARGR------NPSELTERGFATEEYK-----MALRR---KNKHFRS--
------IRPT------------LTVRSL----------------SELEL-----PAAGKA
RPAPAKDAEPSA---------------GAHPG----------TPPAQ---ALMDL----P
TAGERL---------EHCTK-ARPRPNRRHK-----------------------------
------QPPSK-P---TVQP---VAHENSEDRSITRVDEGLEDFFTKRLIAEELPSPTVL
ESGPGS-APLASSSSRTLKKKIGNFFAFKKPKSSRSSRCEKEPEGGAAAPRSRRSMLSDI
LRAPSKAGEPGKALSKSEEGALSA----EPEHSQTPEAARRIRPKYSREGKSQSLILLPG
EDE---EALGVRQDKKRH---LEKSDGELPNSFEQRVHVMLHRMGVTKGLV-TESKKQQS
KDSEIKKAGSDGDIVDSSADSPP-SLKARTHSVSTDASLRGP-------SEPSPAWKALG
RQLNAELTGLGR----EQLRRCSAGPEQSGQPACREAWSSSLPRQGRSHTGEPTAGTALP
PSPCSAAEDNRLTSRLAVLGARRAVSVHEEQLREPECLAELGTATIPLRLRRSPVLKRRP
EASGEPRPAAEAGGTAAQDRLQAALDEAQTAA---G---VLHGERPPAAAQTVVYAQDSA
VDQRSPVPGLGEPALGQ

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--------------------------MPLPLSDVTQAHRSRPELTTRAVHQIQACLWRNN
QADS-TSDLKPCLQPLGLISDHSEQEVNELCQSVQEHMELLGCGAGPQGEVAVHQA----
-EDAIQNANFSLSILPILY----EAGRSPSHHWQLQQKLESLLGQVGEICRQDIQ-----
-------DFTQTTLDT

PF16000 // ENSGT00390000014487_1_Domain_4 (977, 1415)

TRSLCPQMLQTPGWRKQLEGVLVGSGGL-----PELLPEHLLQD
AFSRLRDMRLSIT--GTLAESIVAQALAGLHAARDRLVES----------LTQQAPVTMA
PAVPPL-GGNELSPLETGGL------EEL--FFPTEKEEEREKD---------ESSSWKW
LEP------------SNCFHLVSSL-----------------------HGVAEEAERDPE
LAAPGEDAEPQA---------------GPSARGSPSPAAP---GPPAGPLPRMDL----P
PAGQ-P--------LRH-PTRARPRPR-RQHHH---------------------------
------RPP---PGGPQVPPALLQE----GNGLTARVDEGVEEFFSKRLIQQDHFWAP--
EEDPAT-EGGATPVPRTLRKKLGTLFAFKKPRSTRGPRPDLETSPG-AAARARKSTLGDL
LRPPARPGRG-EEP-----------GGAEG-GTSSPDPARRNRPRYTRESKAYSMILLPA
EE---EAAVGTRPDKRRP---LERGDTELAPSFEQRVHVMLQRIGVSRGSGGAESKRKQS
KDGEIKKAGSDGDIMDSSTETPPISIKSRTHSVSADPSCRPGP---GGQGPESATWKTLG
QQLNAELRGRGWGQQDGPGPP-------SP---CPS------PSPRRTSPAPDILSLPED
PCLGPRNE----------------------------ERP----L----RLQRSPVLKRRP
KLEAPP-SPS-LGSGLGSKPLSPYPTEPS--S-P------ERSPPSPATDQ-----RGGG
PN----P----------

------------------------------------------MAQ-TPDGISCELQGEIT
RFLWPKEVELLLKTWLPG-EGA---VQNHVLALLRWRAYLLHTTCLPLRVDCTFSYLEVQ
AMALQETPPQVTFEL-ESLRELVLEFPGVAALEQLAQHVAAAIKKVFPCSTLGKLFRRPT
PASMLARLE-RSSSSEST--DPCSPCGGFLETYEALCDYNGFPFREEIQWDVDTIYHRQG
CRHFSLGDFSHLSS----RDLALSVAALSYNLWFRCLSCVDMKLSLEVSEQILHMMSQSS
HLEELVLETCGLRG--------------DFVRRLAQVLAGHS

PF13516 // ENSGT00390000014487_1_Domain_0 (343, 378)

SSGLRELSLAGNLLDDRG
M-------------AALSRFLERCPGALRRLNLAQTGLTPR-------------------
-------GMRALGQALATNA-AFDSILTQLDLSGNPGALGPSEDSGGLYTFLS----RPN
VLSFLSLAGTDTALDIVRGCSVGGWMIC------RVDWRV------G-PPTGATNTLPPQ
LFAALSRGCCASLTHLDASRNVFSRTKSRAA-----PAALQLFLSRAGTLRHLGLA---G
CKLPPDALRALLDGLALNTHLRDLHLDLSACELRSAGAQVIQDLVCDAGAVSSLDLADNG
FGSDMVTLVLAIGRSRSLRHVALGRNFNVRCKETLDDVLHRIVQLMQDDDCPLQSLSVAE
SRLKLGASVLLQALA

PF13516 // ENSGT00390000014487_1_Domain_3 (736, 760)

TNP-NLTALDISGNAVGDAGAKLL

ENSGT00390000014487_1_Linker_3_4 (760, 977)

AKALRVNSRLRSV---VWDRN
HTS----------------------AMPLPLNDVAQAQRSRPELTARAVHQIQACLLRNN
RADPASSDHTTHLQPLSLVSEPSEQEVNELCQSVQEHVELLGCGAGPQGEAAVRQA----
-EDAIQNANFSLSILPILY----EAGSSPSYHWQLGQKLEGLLGHVGEVCRQDIQ-----
-------DFTQATLDT

PF16000 // ENSGT00390000014487_1_Domain_4 (977, 1415)

ARNLCPQMLQGSSWREQLEGVLAGLRGL-----PELLPEQLLQD
AFTRLRDMRLSIT--GTLAESIVAQALAGLSAARDRLVES----------LAQQATVTMP
PSLPAL-NGGQPSPLERGEL------EGL--FFSKEEKEEE-------EEEKDDSPARKW
PEL------------SHSLHLVPFIHSAAE-----------------------EAEPEPE
LAAPGEDAE---------------PQAGPSARGSPSPATP---GPSAGPLPRMDL----P
SAGQ-P--------LRHPTR-ARPRPR-RQHHH---------------------------
------RPP---PGGPQVPPALPQE----GNGLSARVDEGVEEFFSKRLIQQDRLWAP--
EEDLAT-EGGTTPVPRTLRKKLGTLFAFKKPRSTRGPRPDLETSPG-AAPRTRKTTFSDL
LRPPTRPSRGEEP------------GGAEG-DTSSPDPARRSRPRYTRDSKAYSMILLPA
EEE---AMLGARPDKRRP---LERGETELAPSFEQRVQVMLQRIGVSRGSGGAEGKRKQS
KDGEIKKAGSDGDIMDSSTEAPPISMKSRTHSVSADPSCRPGP---GSQGPESATWKTLG
QQLNAELRSRGWGQQDGPGPP-------SP---GQS------PSPCRASPSPDSLGLPED
PCLGPRSEDGQL-RPRPLSAGRRAVSVHEDQLQAPAERP----L----RLQRSPVLKRRP
KLEAPP-SPS-LGSGLGTEPLHPQPTEPS--S-P------EWSPPSPATDQ-----RGGG
PN---P-----------

------------------------------------------MAQTPD-GISCELRGEIT
RFLWPKEAELLLKTWLPEREGA---EQGHVLALLRWRAYLLH-TCLPLRVDCTFSYLEVQ
AMALQETPPQVTFEL-ESLPDLVLEFPGVAALEQLAQHIAAAIRKVFPRSTLGKLFRRPT
PPSMLARLE-RSSPSEAT--SPSSPCGGFSETYEALCDYNGFPFREEIQWDVDTIYHRQG
CRHFSLGDFSHLGS----RDLALSVAALSYNLWFRCLSCVDMKLSLEVSEQILHMLSQSS
HLEELVLETCGLRG--------------DFVRRLAQVLAGHMTSG

PF13516 // ENSGT00390000014487_1_Domain_0 (346, 378)

LRELSLAGNLLDDRG
M-------------AALSRHLERRPGALRRLSLAQTGLTPR-------------------
-------GMRALGRALASNA-AFDSVLTHLDLSGNPGALGASEDNGGLYSFLS----RPN
VLTFLNLSGTDTALDT--------------------------------------------
LFAALSRGCCTSLVHLDASRNVFSRMKSRAA-----PDTLQLFLSHAGMLRHLGLA---G
CKLPPDALRALLEGLALNTHMDDLHLDLSACELGSVGAQVIQDLVCDAGAVSSLDLADNG
FGSDMVTLVLAIGRSRSLRHVALGRNFNVRCKETLDDVLHRIVQLMQDDDCPLQSLSVAE
SRLKLGASVLLRALG

PF13516 // ENSGT00390000014487_1_Domain_3 (736, 760)

TNP-NLTALDISGNAMGDTGAKML

ENSGT00390000014487_1_Linker_3_4 (760, 977)

AKALRVNTRLRSV---VWDRN
HTSALGLLDVA---QALEQN-RSLKAMPLPLNDVAQAQRSRPELTARAVHQIQACLLRNN
RADHASADRTSRPQPLGLGSDPSEQEVNELCQSVQEHVELLGCGAGPQGEAAVHQA----
-EDAIQNANFSLSILPILY----EAGSSPSHQWQLRRKLEGLLGQVGEVCRRDIQ-----
-------DFTQATLDT

PF16000 // ENSGT00390000014487_1_Domain_4 (977, 1415)

TRSLCPQMLQGPRWREQLEGVLVGSRGL-----PELLPEHLLQD
AFTRLRDMRLSVT--GTLAESIVAQALAGLSAARDRLVES----------LAQQATEAVP
PVVPAV-EGGDPSPLGPRQL------KDL--FFPEEKEQE--DEEDQKDD----SPPEKW
PVS------------SHCLHTHSAAE-----------------------EPE------PE
LAAPGEDAEPQA---------------GPSARGSPSPATP---GPPADPPPRMDL----P
PAGQ-P--------LRH-PTRARPRPR-RQHHH---------------------------
------RPP---PGGPQVPPALPQE----GNGLSARVDEGVEEFFSKRLIQQDRLWAP--
EEDPAT-EGGSTPVPRTLRKKLGTLFAFKKPRSTRGPRPDLETSPG-AAPRTRKTTLGDL
LRPPARSGRGEEP------------GGAEG-GTSSPDPTRRSRPRYTRESKAYSMILLPA
EEE--ETTLGARPDKRRP---LERGDTELAPSFEQRVQVMLQRIGVSRGSGSADGKRKQS
KDGEIKKAGSDGDIMDSSTETPPISIKSRTHSVSADPSCRPGP---GGQGPEPATWKTLG
QQLNAELRGRGWGQQDGPGPP-------SP---CPS------PSPRRASPSPDSLGLPED
PCLSSQNTDGQL-RPRPLPAGRRAVSVHEDQLQAPVERP----L----RLQRSPVLKRRP
KLETPP-SPS-VGKRGW-GPLGGGRVAQS--T-P-------DPPSLPVSDRIWPWSRASA
PT---DFRALQ-P----