Query Results 

--------MQQNSIKANTIKANITKSGSTKARDLMHRMAIIPDWHILYSRS-GRLTYSQA
HSSPCRV-HSRNGSQG-----GSRSPSS--TINAVNPVLSFF--DVKRIL

PF08976 // ENSGT00390000013629_0_Domain_0 (111, 182)

FQKITSKKDE
LMKVFKMLDTGQNLTVTKGELRRTIATFLLPLTREQFQDVLAQIPLTCSGNVPYLEFLSK
F

ENSGT00390000013629_0_Linker_0_1 (182, 230)

G-GIDLNIN---AAKRVN--GNEMVGCRKVNELEV------SKNMKTI

PF13202 // ENSGT00390000013629_0_Domain_1 (230, 252)

IKAFKLIDVNN
TGQVKPQELRRILEAFCSKMSDE-EYER--------------------------------
-------LCKHYNIDEGTAVDYNMFLKNL-GISNDINSVLF---S---ELLGE-NQQARD
VKKEQLPS-SASSEDTWKSFNLDELERIFSQELLRSFEKIEKALSAGDPSQGGYISLNYL
KVVLDTFIHYLPRRIFIQLMKRGIWHRNK-I--------------------FGSKLLPVQ
LQF-VD---SRNRAYKENIIKKLFLQSEDHHASLKKALLVM-SSVPDGKMPWEELRHILN
CMVTK-LSDSAFKELVQTLDPEGTGMVKISTLLDM-LP-DSPEVRK--VSPPT-DNKTPL
SLDWDSVDKMVCDAISRNLRAFYTMLQSYDLGDTGSISRANFKKVMHIFCPYLKNEHFI-
-KLFSKFYDSVSGRVLYKKLLACLGSSSSAAVSPLLG--SQDQL-SGQFQKEG-QDQPT-
--------GK--TLHQKNMTKEEVIEKLKVRIQQQDPVFRRHFLSVSQTPDGKVSMQDFR
KVLEDSGMPMDDVQYALLASKLGYKK-EGMSYLDFASGFEGYD---CLLWGPERSPP-PT
SASSKP--HVDSYFISAEECLKLFPK---RLKESFRDPYSAFFKVDTDRDGIINMHDLHR
LLLQLLLNMKDEEYERFLGLLGLRLSVTLNFREFQNLCEKRPVRS-DDAPQRSIRTKQKV
ADSELACEQAHQYLALKAKTRWADLSKNFIETDNEGNGILRRRDIKNALYGFDIPLTPRE
FEKLWQSYDTEGRGYITY----QEFLQRLGIHYSPEVHRPYT----EDYFNFLGHFTKPK
QIQEEIQELQQITNR----------TKEKLADHYEDITRGLSTLEKSKTGSVPLCKLQKV
LRDCGCALKEEELTSLL----DSWGVFVHENNYVNHLDFLKALENNSKPRRAQA-GDRE-
---EDAPTNFSTLNLEELVKSVQGVVNASQQPLSEAFSELDKEGTGFLKPTEFGQVLKEF
CHKLTDNQYHYLLRKLGIHLRPSIHWKYFLQNFSSFLEESADEWA---EKMPEVSPPRS-
PK

PF08976 // ENSGT00390000013629_0_Domain_11 (1323, 1444)

DTANKDILARLYKAVTA----HYHTITQEFENFDTMKTNTVSRDEFRAICNRHVQILT
D-------EQFDRLWSELPVNPKGRLKFQDFLSRFSIERAASPPAMTTA---TGDSI---
AAQRGSSAPEVS-EATRSAISS-PLRDQRR--G-LKSRSHPGTPV---------------
-GTPPLQNLEPIENKLRRQMQGCWRELLKECKEKDVNKQGTITASEFLALVEKFNLDISK
EESQQLIVKYDLKNNGRFAYCDFIQSCVLLLKAKETSLMQRMKIQNANKMKEAGAESPSF
YSALLRIQPKIVHCWRPMRRSFKTYDEGG

PF13833 // ENSGT00390000013629_0_Domain_17 (1650, 1698)

SGLLSVANFRKVLRQYGINLSEEEFFHLLEY
YDKTLSSKISYNDFLRAFLQ----------------------------------------
---------------

----------------------------------MCKMAIIPDWLRSYPHM-RKFTHSRP
HSSPCRV-YSRNGSPD-----IFRSSS---TTAVANPTLSCL--DVKRILFQKITDR

PF08976 // ENSGT00390000013629_0_Domain_0 (118, 182)

GDE
LQKAFQLLDTGQNLTVSKSELRRIITDFLMPLTREQFQDVLAQIPLSTSGTVPYLAFLSR
F

ENSGT00390000013629_0_Linker_0_1 (182, 231)

G-GIDLYIN---GIKREG--GNEMNCCRTLKELEIQVGEKVFKNIKTVL

PF13202 // ENSGT00390000013629_0_Domain_1 (231, 253)

KAFKLIDVNK
TGLIQPQELRRVLETFCLKLRDE-EYEK--------------------------------
-------FSKHYNIHNDTAVDYNVFLKNL-SINNDLNLRYCIGNQ---EVSLE-NQQAKN
SKKERLLS-SASSEDTWRNYSLDEIERNFCLELSKSYEKIEKALSAGDPCKGGYVSFNYL
KIVLDTFIYQIPRRIFIQLMKRFGLKATTKINWKKFLTSFHEPR----GLEITSKGPLTK
RNS-IN---SRNESHKENIITKLFRHTEDRFTSLKKALLII-NTKP

PF13833 // ENSGT00390000013629_0_Domain_4 (527, 580)

NGPITREEFRHILN
CVTVK-LSDSEFKELMQTLDPGNTGVVNISVFIDL-VE-KNSRMRK--ASPCT-DTKTPF
LLAWDSVEEIVHDTITRNLHAFYNMLRAYDLGDTGLIGRNNFKKILHVFCPFLTNAHFI-
-KLCSKIQDIGSGRILYKKLLAHMGIDGPPTVSPVHV--PKDQLLSEHLRKDE-QQQPDL
SERTKPTENK--TTQIKKMTTEEVIEKFKNCIQQQDPEFKKRFLDFSKEPNGKINVHDFK
KVLEDTGMPMDDEQYALLTTKIGFEK-EGMSYLDFAAGFED-----PPMRGPETTPP-QP
PTPSKS--YVNSHFITAEECLKLFPR---RLKESFRDPYSAFFKIDTDRDGIINMHDLHK
LLMHLLFNLRDDEFERFLGLLGLRLSVTLNFREFRNLCEKRSLKT-DEAPQRLIRPKQKV
ADSELACEQAHQYLVTKAKNRWSDLSKNFLETDNEGNGILRRRDIKNALYGFDIPLTPRE
FEKLWASYDTEGKGHITY----QEFLQKLGVNYSPAVHRPCA----GDYFNFMGHFTKPQ
QLQEEMKELQQST-------EKAVAARDKLVDCYQDISKAFTKIDKSKTNYISICKMQKV
LEECGCSLTEGELTNLLN----SWGVSRHD-NSINYLDFLRAVEN-SKSTGAQP-KEKE-
---ESMPINFATLNPQEVVRKIQEVVESSQLALSMAFSALDKEDTGFVKSTEFGQVLKDF
CHKLTDNQYHYFLRKLRIHLTPYINWKYFLQNFSCFLEETAEEWA---EKMPKGPPPTS-
PKA

PF08976 // ENSGT00390000013629_0_Domain_11 (1324, 1437)

VASRDILARLHKAVTS----HYHAITQEFENFDTMKTNTISREEFRAVCNRNVQILT
D-------EQFDRLWNEMPVNAKGRLKYPDFLSRFSSERAATPTA-------TGDSA---
AAHRGSSVPDVS-EGIRSAL-SLPNQELRP--G-SKSQSHPCTAA----------STTAI
LGTPPLQNCDPIESRLRKRIQGCWRQLLKECKEKDVARQGDISASEFLALVEKFNLDISK
EECQQLIIKYDLKNNGKFAYCDFIQSCVLLLKAKESSLMQRMKIQNAHKMKDAGAETSSF
YSALLRIQPKIVHCWRPMRRTFKSYDEAG

PF13833 // ENSGT00390000013629_0_Domain_17 (1650, 1698)

TGLLSVADFRTVLRQYSINLSEEEFFHILEY
YDKTLSSKISYNDFLRAFLQ----------------------------------------
---------------

----------------------------------MCKMAIIPDWLRSHPHM-RKFTHSRP
HSSPCRV-YSRNGSPD-----IFRSSS---TTAVANPTLSSL--DVKRILFQKITD

PF08976 // ENSGT00390000013629_0_Domain_0 (117, 182)

RGDE
LQKAFQLLDTGQNLTVSKSELRRIITDFLMPLTREQFQDVLAQVPLSTSGTVPYLAFLSR
F

ENSGT00390000013629_0_Linker_0_1 (182, 231)

G-GIDLYIN---GIKREG--GNEMNCCRTLRELEIQVGEKVFKNIKTVL

PF13202 // ENSGT00390000013629_0_Domain_1 (231, 253)

KAFKLIDVNK
TGLIQPQELRRVLETFCLKLRDE-EYEK--------------------------------
-------FSKHYNIHNDTAVDYNVFLKNL-SINNDLNLRYCIGNQ---EVSLE-NQQAKN
SKKERLLS-SASSEDTWRNYSLDEIERNFCLELSKSYEKIEKALSAGDPCKGGYVSFNYL
KIVLDTFIYQIPRRIFIQLMKRFGLKATTKINWKKFLTSFHEPQ----GLEITSKGPLTK
RNS-IN---SRNESHKENIITKLFRHTEDRFTSLKKALLVI-NTKP

PF13833 // ENSGT00390000013629_0_Domain_4 (527, 580)

NGPITREEFRHILN
CVAVK-LSDSEFKELMQTLDPGNTGVVNISVFIDL-VE-KNSRMRK--ASPCT-DTKTPF
LLAWDSVEEIVHDTITRNLHAFYNMLRAYDLGDTGLIGRNNFKKILHVFCPFLTNAHFI-
-KLCSKIQDIGSGRILYKKLLAHMGIDGPPTVSPVHV--PKDQLLSEHLRKDE-QQQPDL
SERTKPTENK--TTQIKKMTTEEVIEKFKNCIQQHDPEFKKRFLDFSKEPNGKINVHDFK
KVLEDTGMPVDDEQYALLTTKIGFEK-EGMSYLDFAAGFED-----PPMRGPEATPP-QP
PTPSKS--YVNSHFITAEECLKLFPR---RLKESFQDPYSAFFKIDTDRDGIINMHDLHK
LLVHLLFNLRDDEFERFLGLLGLRLSVTLNFREFRNLCEKRSLKT-DEAPQRLIRPKQKV
ADSELACEQAHQYLVTKAKNRWSDLSKNFLETDNEGNGILRRRDIKNALYGFDIPLTPRE
FEKLWASYDTEGKGHITY----QEFLQKLGVNYSPAVHRPCA----EDYFNFMGHFTKPQ
QLQEEMKELQQST-------EKAVAARDKLVDCYQDVSKAFTKIDKSKTNYISICKMQKV
LEECGCSLTEGELTNLLN----SWGVSRHD-NSVNYLDFLRAVEN-SKSTGAQP-KEQE-
---ESMPINFATLNPQEVVRKIQEVVEFSQLALSMAFSALDKEDTGFVKSTEFGQVLKDF
CHKLTDNQYHYFLRKLRIHLTPYINWKYFLQNFSCFLEETAEEWA---EKMPKGPPPTS-
PKA

PF08976 // ENSGT00390000013629_0_Domain_11 (1324, 1444)

MASRDILARLHKAVTS----HYHAITQELENFDTMKTNTISREEFRAICNRNVQILT
D-------EQFDRLWNEMPVNAKGRLKYPDFLSRFSSERAATPTA-------TGDSA---
AAQRGSSVPNVS-EGIRSAF-SLPNQELRP--G-SKSQSHPCTAA----------STTAI
PGTPPLQNCDPIESRLRKRIQGCWRQLLKECKEKDVARQGDISASEFLALVEKFNLDISK
EECQQLIIKYDLKNNGKFAYCDFIQSCVLLLKAKESSLTQRMKIQNAHKMKDAGAETSSF
YSALLRIQPKIVHCWRPMRRTFKSYDEAG

PF13833 // ENSGT00390000013629_0_Domain_17 (1650, 1698)

TGLLSVADFRTVLKQYSINLSEEEFFHILEY
YDKTLSSKISYNDFLRAFLQ----------------------------------------
---------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------LWNRYSLGKDTSLDYNAFLKNL-AMNINLNQKYSTSNK---------------
---------SSLSGDSWENSSMDEIEAAFCREFGVCTA

PF00036 // ENSGT00390000013629_0_Domain_2 (399, 427)

NIEKALSAFDTSKRGYVSLNYL
KIVVDNFIFPLPKGIFLQLLKRLGFKTTGKIAWKQFLRKCQEPV----DN--GSMIPLRK
KKXXXX---XXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXKQDGKILGKELRHVLN
CALLK-ISDV

PF00036 // ENSGT00390000013629_0_Domain_4 (551, 580)

EYKELLQILDPTGSGYVNYFTFLYL-LEEIRK------KTEWT-DEKIPQ
FLAWDSMEEVLQDALSKNLQDFYTLLKTYDIGDTGLISRNNLKKVLQTFCRYLSDEHLS-
-KLCDKFQDATSGGILYKKLLASFGIIIPIYESPVTV--QSFQSLNGI------GRRDDF
SERSKSNDYK--SEPIKNKTLEEVIDSLKNWIQLQDLAS-GIFLEYSKHPLEKISKEEFR
KVLEDNGMPMDDEQFGLLVKKIGYKN-EGLSYLDFASGFEXXXXX-----XXXXXXX-XX
XXXPKS--SFESHFTSAEECLKNFPK---RIKEFYG

PF00036 // ENSGT00390000013629_0_Domain_6 (877, 905)

DAYSAFYKTDTNRDGLINMADLRT
MLHHMLITLKEEEFMHLLDLMNLKPGLTLNYREFRNLCEKKQFKK-DDPPQRLIXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXYDVSQKGYVTY----QEFLNRLGIEYSPSIHRPYA----VDHFNFMGHFTKPE
QILEETRELQQYLEE-------AVEVRDKLKDHYQ

PF00036 // ENSGT00390000013629_0_Domain_9 (1116, 1144)

DISQAFAKLDRHKNASVSLNEMQKV
LQEYQPNITEEEIITMLK----SWGISYND-NIICYHEFLKAFDN-LKPTKTHP-KEKE-
---ESQTVVFSTLPPDQVLKKMKEV----------AFAAYDKEDTGIIKASDFAQVIKDL
CLKLKDSQYTYVLKKLRLHLNTHINWKFFLRNFPCFFEETAAEWT---DKMEGLWP-RS-
PKDQFLKDILTRIRDIVTT----RYLNIAQEFSDLDCLKSNLISREDFRSVFNRHIQILN
D-------EQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------X-------
XXXXXXXX------XXXXXXXXXXXXXXXX--X-XXXXXXXXXXX----------XXXXX

PF08976 // ENSGT00390000013629_0_Domain_13 (1501, 1525)

PGVPPLQNCEMIETKVRKKIQGCW

ENSGT00390000013629_0_Linker_13_14 (1525, 1526)

K

PF00036 // ENSGT00390000013629_0_Domain_14 (1526, 1554)

EMLKECKEKDVDKRGEITVAEFQALVDK

ENSGT00390000013629_0_Linker_14_16 (1554, 1637)

YNLEISK
EECQHLITKYDLKSNGKFAYCDFFQSCVLLLKTKETSLMQRMKIQQVYMMKGSGTQSASF
YAALLRIQPKILHCWR

PF00036 // ENSGT00390000013629_0_Domain_16 (1637, 1665)

PMRRTFKSYDESGTGLLSIADFRKVLRQYGINLSEEEFFHILEY
YDRTLSSKISYNDFLRAFLQ----------------------------------------
---------------

----------------------------------MSKMANIPYWLTSYHPT-QKFTYSRP
HSSPCRV-YSRNGFQN-----MFRPSS---TTAVANPILSSL--DVKRILFQK

PF08976 // ENSGT00390000013629_0_Domain_0 (114, 187)

ITNKGDE
LKKTFQLLDTGQNLTVSKSELRRIITDFLMPLTREQFQDVLAQIPLTSSGTIPYLEFLSR
FG-RID

ENSGT00390000013629_0_Linker_0_1 (187, 231)

TNIN---VIKRGS--GNKMNCCRTLKELEIQVGEKVFKNIKTVI

PF13202 // ENSGT00390000013629_0_Domain_1 (231, 253)

KAFKLIDVNK
TGLVQPQELRRVLEIFCLKFRDE-EYEK--------------------------------
-------FSKHYNINKDTAVDYNVFLKNL-SINNDLNLRYFMENQ---EVSSE-NQQTQN
SKKEHLLS-SMSSEAIWQNYSLDEIERTFYQEFSKSYEKIEKALSAGDPSKGGYVSFNYL
KIVLDTFVCRLPRRIFIQLLKRFGLKPTTKINWKQFLTSFYEPQ----GLAFSSTASLTK
RNS-IN---SRNQSHKENIITKLFRNAEDCYTSLKKALLII-NSKP

PF13833 // ENSGT00390000013629_0_Domain_4 (527, 580)

DGQVAGEDLRHILN
CMVVK-LSDSEFKELMHTLDPADTGMVNISTFIDL-LE-EEPKMRK--TALCT-GTKTPL
FLAWDSVEGIVHDAITRNQQAFFNTLQSYDLGDTGLISRNNFKKIMQTFCPCLTNEHLI-
-KLCSKFQDIASGRILYKKLLACVGVNGPPTVSPILV--PKNQLFDEGFQKEE-QQQPDL
SERTKPTEDK--TTLIKSMTKEEVIENLKNCIQQQDPTFRKRFLDFSKGPDRKININDFK
KVLEGSGMPMDDDQYALLTAKIGYKK-EGMSYLDFAAGFEE-----APMSGPEATPPP-T
PASSKS--HVHNHFVTAEECLKLFPK---RLKESFRDPYSAFFKMDTDRDGIINMYDLHR
LLQHLLFNLKDNEFERFLGLLGLRLSVTLNFREFRNLCEKRTIRT-DDPPQRLIRPKQKV
ADSELACEQAHQYLVTKAKNRWSDLSKNFIETDNEGNGILRRRDIKNALYGFDIPLTPRE
FEKLWASYDTEGKGHITY----QEFLQKLGINYSPTVHRPYA----EDYFNFMGHFTKQQ
QVQEEMRELQQST-------EKNTPARDKLMDHYQDIIKTLTKIDKSKNGYISISKMQKV
LQECGCFLKEEELTSLLN----SWGISQHD-NSINYHDFLKALEN-SKPTRPQP-KEGE-
---ECAPVNFSTLTPEEIVKNIQEVVDSSQAALLTAFSALDKENTGFVKATEFEQVLKDF
CYKLTDNQYQYFLRKLRIHLAPYIHWNYFLQNFNCFLEEMADEWA---EKMPKGPPPGS-
PKA

PF08976 // ENSGT00390000013629_0_Domain_11 (1324, 1444)

VANRDILARLHKAVTS----RYHAIAQEFENFDTMKTNTASRDEFRAICTRHVQILT
D-------EQFDRLWSEMPVNAKGRLRYLDFLSRFNTETAATPTA-------TGDSM---
VAQRGSSVPEIS-EGATSAV-PSSTRDLRT--G-SKLRGQPCTPA----------STVTI
PCPPPLQNCEPIETKLRKRIQGCWRELLKQCKEKDVNKQGEITTAEFLALVEKFNLDINK
EECQQLVIKYDLKNNGKFAYCDFIQSCVLLLKAKETSLMHRMKIQNAHKMKEAGAETSSF
YSALLRIQPQIMHCWRPMRRTFKTYDEAG

PF13833 // ENSGT00390000013629_0_Domain_17 (1650, 1698)

TGLLSVADFRKVLRQYSINLSEEEFFHILEY
YDKTLSSKVSYNDFLRAFLQ----------------------------------------
---------------

--------MKRNST-----KGNSTKSGSTKARNLMNKMMNVPDWRALYPPI-RKFTSSRP
HSSPCRV-YSKNGFQN-----MLRPSSS--PSAAANPVLSFL--DVKRILFQ

PF08976 // ENSGT00390000013629_0_Domain_0 (113, 182)

KITDKKDE
LKKAFQLLDTGQDLTVTRGELKRIIATFLLPLTREQFQDVLAQIPLTSSGGVPYFEFLSR
FG-GTDLNIN---VIKRGV--GNEMDRCRTLKELEMQVGEKIFKNLKTVTKAFQLIDVNH
RGLVQPQELRRVLETFCLRMTEE-EYRK--------------------------------
-------FSKHYNIDKDPVVDYSLFLKNL-SKSNDLHLRYFMANP---EVSPE-SQQART
SKREQFLI-SEPPEESWSNYSLDDVERTFCQEFSKSVDKIEKALSAGDPSRGGYVSLNYL
KIVLDTFVYRLPRRIFLQLMKRFGFKTTSRINWKQFLTSFYELQ----RSEVNNIVPPLK
RDC-IN---AGNQSGKESAVTKVLRHAEYSCGALKKALLMTGASK

PF13833 // ENSGT00390000013629_0_Domain_4 (526, 578)

PNGEITGEELRQILS
STVVK-LSDSEFKELMKTLDSRGTGMVAVSSFFDL-LE-GDPKMRK-ASSPCT-GAKTPL
SLAWDSVEEMVHDAVAKNLQAFCNMLQSYDLRDTGFITRNHFKKVMRIFCPFLTNKHLI-
-KLCCKFQDMTSENILYKKFLACFRINAPPMVSPVLV--PEDQS-RERFQKGG-EWQPAL
SERTEPTRNR-----TKNMTKDEVTEKLKSYIKWQDPAFRKRFLDVSQGLHRKISLRDFR
KVLEASGMPMDEEQFWLLATKIGYKK-EGMSYLDFTAGFEE-----AKTNGPAATPP-QT
PISSKN--HLNGHFITAEECLKLFPK---RLKESFRDPYSAFFKIDSDRDGIINMRDLHR
LLQRLLFNLKDEEFERLLGLLGLRLSVTLNFREFQNLCEKGPSRM-DDAPQRLIRPKQKV
ADSELACEQAHQYLVIKAKNRWADLSKNFIETDTEGNGILRRRDVKNALYGFDIPLTPRE
FEKLWQSYDTEGRGYITY----QEFLQKLGINYSPTVHRPYA----EDYFNFLGHFTKPQ
QIQEEIQELQQSTEK----EKEHMPAGDHLVDHFEDISKVLSALDKSQSGSVSLCKMQQV
LQECGCPLKEEELTSLLN----SLGIICHD-STINYLDFLRALEK-GKASRPQP-REKE-
---ESVPVNFSTVNPEAVVKSIQEVVSASQLALLQAFSALDKEDTGFLKAADFGQVLKDF
CYKLTDSQYHYFLRKLRIHLMPYIHWKYFLENFGCFLEETADEWA---EKMPRIPPPAS-
PR

PF08976 // ENSGT00390000013629_0_Domain_11 (1323, 1441)

EAAHRELLARLHKAVTS----HHRAFAQELENFDTGKTNTVSRDEFRATCTRHLQTLT
D-------EQFDRLWSEMPVNAKGRLKYQEFLSRFSAERAATPPA-------TGDSV---
QAQKGSSVPEIS-EGTRSAV-ASPTRDLRA--G-LKSRSHPCTPA---------------
-GTPPLQNCEPIESRLRRQVQGCWRELLKECKEKDTGRLGTITAPEFLALVEKFRLDVSK
EESQQLLVKYDLRDNGTFAYCDFIQSCVLLLRPKETSLMQRMRIQNAHKMKEAGAETASF
YSALLRIQPKILHCWRPMRRMFKAYDEGGTGLLSTDDFRKVLRQFSINLSEEEFFHLLEY
YDKTLSSRVPYNDFLRAFLQ----------------------------------------
---------------

--------MKRNGTRPNFAKANSTKSGSTRARDLMNKMAIIPEWHSLYPNT-RKLPCSRP
HSSPCKM-Q-RTIFQD-----LCRPSSS--TTAIANPVLSYL--DIERILSQKISSRRDD
IKKVFQILDRNHNQTVTKGDLKRVITAFLIPLTKDQFQDLLAQIPISSLGNVPYLEFLSR
FGGGTDININ---GIKRVN--ENEVDNRRTLKEV--QLTEKIFQNMRS

PF13202 // ENSGT00390000013629_0_Domain_1 (229, 253)

IRKVFQVMDVNN
TGLVQPQELRRVLETFCLRMQDG-DYEK--------------------------------
-------FLEQYNLDKTTAVDYIAFLKNL-SVKNDASFKYLLSNA--AELSRE-TQQGKN
GK--RPLD-TGSSEDVWKNYSLDDLEKTFCQEFSKSYEKIEKALSAGDPSKGGYISLNYL
KVVLDTFIYRLPRRIFIQLIRRFGLKTSTKINWKQFLTAIYERQ----KLEVSKTLPLKK
RSS-TE---ARNRSRKENIIKKLFKYSEDRYTALKKTLLII-SSTPSGHITWEELRHILN
CMVAK-LNDSEFSELKQTFDPEGTGAVRVNSLLDV-LD-DSTKVRK--MSPST-DTKTPL
PVAWDSVEELVLDSITRNLQAFYSMLQSYDLRDTGTIGKNNFRKVMRVFCPYLSNEHLV-
-RFSSKFQEAGSGRILYKKFLLSIGVGIPPPIPLLSS--LKVQL-SDQFQTEE-PGQQ--
GERTQPSGDK--TSEINNMTKEEVIDSLKHRIQQKDSVFRKQFLSISKEPDVKINQEEFR
KVLERSGMPMNDCQYSMLASKLGFKNEEGMSYQDFTMGFED-----CMLRGLETVPL-QS
RTASRM--NMDEHFISAEECLRIFPK---KLKESFRDVYSAFF

PF13202 // ENSGT00390000013629_0_Domain_6 (884, 901)

RIDLDRDGIISMHDLHR
LLQYLQLNMVDLEFERFLSLLGLRLSVTLNFREFQNLCEKRPWKS-DEAPQRLIRCKQKV
ADSELACEQAHQYLIMKAKTRWADLSKNFIETDNEGNGILRRRDIKNSLYGFDIPLTPRE
FEKLWQNYDTEGRGYITY----QEFLQRLGIRYSPKVHRPYK----EDYFNFLGHFTKPK
QVQEEIQELQQISER------------EKLMNHYEEISKAFNAMEKSK--PVALCRVQKV
LQECGCPLKEEELISLLK----SLDVSVHN-NHIDPVEFLRALEI-SWASKARP-KEK--
EESSPPPISFSKLTPDEVIKTMQEVVESSQPALVKAFSALDKEDTGFVKAMEFGDVLRSV
CQKLTDNQYHYFLRRLRLHLTPNIHWKYFLENFSTFQDETADEWA---ENMPKAPPPTS-
PK

PF08976 // ENSGT00390000013629_0_Domain_11 (1323, 1444)

ETAHRDIVARVQKAVAS----HYHTIVQEFENFDTLKNNTVSRDEFRSICTRHIQILT
D-------EQFDRLWSELPVNAKGRLKYQDFLSKLSIERVPSPPMAAGD---SGEST---
MAQRGSSAPEFS-QGTRSNL-YSPPRDSRV--G-LKSRSHPCTPV---------------
-GTPPLQNCEPIESRLRKQIQGCWRELLRECKEKDMDKQGTISAAEFLALVEKFKLDISR
EESQQLIVKYDLKNNGKFAYCDFIQSCVLLLKAKETSLMRRMKIQNADKMKEAGMETPSF
YSALLRIQPKIVHCWRPM

PF13499 // ENSGT00390000013629_0_Domain_17 (1639, 1698)

RRSFKTYDENGTGLLSVADFRKVLRQYSINLSEEEFFHVLEY
YDKSLSSKISYNDFLRAFLQ----------------------------------------
---------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------TVRQALGGDAGQR

PF08976 // ENSGT00390000013629_0_Domain_11 (1403, 1444)

QGRLKYLDFLSTFSSEKAATPPA-------TDDSA---
KAQRGSSVPEVS-EGGRSAGSS-PTRNLRT--G-SKQQSHPCSPV----------G----
-AALPLQNCELIENKLRKRLQGCWRKFLRECKDRDAGKRGEIAPADFLALAEKFNLDINR
DECQQLIVKYDLKNDGTFAYCSFIQSCVLLLRAKESSLLQRMKIQNANKMKEAGAETSSF
YCALLRIQPRIAHCWRP

PF13405 // ENSGT00390000013629_0_Domain_16 (1638, 1664)

MRRAFKAHDQGGTGFLSVADFRKVLRQYSVILSEEEFFHVLEH
YDKTLSAKIPYNDFLRAFLQ----------------------------------------
---------------

----------------------------------MCKMAIIPDWLRSHPHM-RKFTHSRP
HSSPCRV-YSRNGSPD-----IFRSSS---TTAVANPTLSSL--DVKRILFQKITD

PF08976 // ENSGT00390000013629_0_Domain_0 (117, 182)

RGDE
LQKAFQLLDTGQNLTVSQSELRRIITDFLMPLTREQFQDVLAQIPLSTSGTVPYLAFLSR
F

ENSGT00390000013629_0_Linker_0_1 (182, 231)

G-GIDLYIN---GIKREG--GNEMNCCRTLRELEIQVGEKVFKNIKTVL

PF13202 // ENSGT00390000013629_0_Domain_1 (231, 253)

KAFKLIDVNK
TGLVQPQELRRVLETFCLKLRDE-EYEK--------------------------------
-------FSKHYNIHNDTAVDYNVFLKNL-SINNDLNLRYCIGNQ---EVSLE-NQQAKN
SKKERLLS-SASSEDTWRNYSLDEIERNFCLELSKSYEKIEKALSAGDPCKGGYVSFNYL
KIVLDTFIYQIPRRIFIQLMKRFGLKATTKINWKKFLTSFHEPR----GLEITSKGPLTK
RNS-IN---SRNESHKENIITKLFRHTGDRFTSLKKALLII-NTKP

PF13833 // ENSGT00390000013629_0_Domain_4 (527, 580)

NGPITREEFRHILN
CVAVK-LSDSEFKELMQTLDPGNTGVVNISVFIDL-VE-KNSRMRK--ASPCT-DTKTPF
LLAWDSVEEIVHDTITRNLHAFYNMLRAYDLGDTGLIGRNNFKKILHVFCPFLTNAHFI-
-KLCSKIQDIGSGRILYKKLLAHMGIDGPPTVSPVHV--PKDQLLSEHLRKDE-QQQPDL
SERTKPTENK--TTQIKKMTTEEVIEKFKNCIQQQDPEFKKRFLDFSKEPNGKINVHDFK
KVLEDTGMPMDDEQYALLTTKIGFEK-EGMSYLDFAAGFED-----PPMRRPETTPP-QP
PTPSKS--YVNSHFITAEECLKLFPR---RLKESFRDPYSAFFKIDTDRDGIINMHDLHK
LLVHLLFNLRDDEFERFLGLLGLRLSVTLNFREFRNLCEKRSLKT-DEAPQRLIRPKQKV
ADSELACEQAHQYLVTKAKNRWSDLSKNFLETDNEGNGILRRRDIKNALYGFDIPLTPRE
FEKLWASYDTEGKGHITY----QEFLQKLGVNYSPAVHRPCA----EDYFNFMGHFTKPQ
QLQEEMKELQQST-------EKAVAARDKLVDCYQDISKAFTKIDKSKTNYISICKMQKV
LEECGCSLTEGELTNLLN----SWGVSRHD-NSINYLDFLRAVEN-SKSTGAQP-KEKE-
---ESMPINFATLNPQEVVRKIQEVVESSQLALSMAFSALDKEDTGFVKSTEFGQVLKDF
CHKLTDNQYHYFLRKLRIHLTPYINWKYFLQNFSCFLEETAEEWA---EKMPKGPPPTS-
PKA

PF08976 // ENSGT00390000013629_0_Domain_11 (1324, 1444)

MASRDILARLHKAVTS----HYHAITQEFENFDTMKTNTISREEFRAVCNRNVQILT
D-------EQFDRLWNEMPVNAKGRLKYPDFLSRFSSERAATPTA-------TGDSA---
AAQRGSSVPDVS-EGIRSAL-SLPNQELRP--G-SKSQSHPCTAA----------STTAI
PGTSPLQNCDPIESRLRKRIQGCWRQLLKECKEKDVARQGDISASEFLALVEKFNLDISK
EECQQLIIKYDLKNNGKFAYCDFIQSCVLLLKAKESSLMQRMKIQNAHKMKDAGAETSSF
YSALLRIQPKIVHCWRPMRRTFKSYDEAG

PF13833 // ENSGT00390000013629_0_Domain_17 (1650, 1698)

TGLLSVADFRTVLKQYSINLSEEEFFHILEY
YDKTLSSKISYNDFLRAFLQ----------------------------------------
---------------

--------MRRNNVRLNVAKVNSTRSSSTKARDLMHKMSILPDWHSLYPKT-QKLKGSRP
HSSPCRG-RSKTGSQD-----LCRPSSS--ATAIVNPMLTFL--DIERI

PF08976 // ENSGT00390000013629_0_Domain_0 (110, 184)

LSQKISSRRDE
MKKIFQVLDPTHSQTVTKGELKRVIVAFLLPLTKEQFQELLSQIPLTSSGNVLYLEFLSR
FS-GMDLNIN---IIR-------------------------------------------S
TGMVQSQELRRVLETFCLKMKDE-EYEM--------------------------------
-------FLKKYYISGAAVVDYNDFLKNVISITNDLTFRQLSSSP---ELSRD-SQQART
PRRDRQFN-SMSSEDVWKNYTLDDVEKTFCQELSKSYEKIEKALSAGDPSKGGYVSLNYL
KVVLDTFVYHLPRRIFIQLMKRFGIKTTSKVNWKQFLNAFYERR----GLEVNKATPQKK
RSS-TD---SRNQSRKESIIKKLFRYSEERYTALKKALLII-STT

PF13833 // ENSGT00390000013629_0_Domain_4 (526, 571)

PNGHMTWDEFRHILN
CMVVK-LNDSEFQELKHTFDPEGSGSVKVSSLLEA-VD-DSPKVRK--MSP-S-DTKASL
PLAWDSVEEMVLDSITRNLQNFYGMLQSYDLGDTGTIARNNFKKVIRIFCPYLSNEHYV-
-KLSSKFQDTTSGRILYKKLLMSIGINVPTSTFPLSV--PKDQL-SEQLQNEE-QGQPDL
AERTQSMRDK--M---TDTTIEEVIDKLKQFIQEQDPVFKKHFLSISQQPDAKIGLEDFR
KVLEESGMPMNDSQYAILTSKIGYKK-EGMSYQDFTSGFEE-----GKLSGLETVPL-QP
RTSSKT--NLDEYFISAEECLRLFPK---KLKELYRDPYSAFFKVDTDMDGLINMNDLHK
LLQQLQLYMKDSEYERFLGLLGLRLSLTLNFREFENLCEQKPWKS-DEAPQRLIRYKQRV
ADSELACEQAHQYLMVKAKTRWADLSKNFIETDNEGNGILRRRDIKNALYGFDIPLTPRE
FEKLWQNYDIEGRGYITY----QEFLQRLGIRYSSKTHRPYK----EDYFNFLGHFTKPK
QIQEEMQELQQTIDR------------EKLMDHYEEISKSLNMLEKSKTGAVSLCKVQKV
LQDCGYPLKEEELIYLLK----SLSISVHN-NCIDPLDFLRALET-NKTSKAPP-KEKEK
EESIPPPINFSKLNPEEVVKSVQVVVDASQPALFKAFSAIDKEDTGFVKAMDFGDVLKSF
CQKLTDNQYHYFLRKLKIHLTPNIHWKYFLENFDSFLEETADEWA---EKMPKVLAPTA-
PKE

PF08976 // ENSGT00390000013629_0_Domain_11 (1324, 1444)

MANRDILTRVHKAVAS----HYHVIAQEFENFDTTKSNTVSRDEFRSVCTRHVQILT
D-------EQFDRLWGEMPVNAKGRLKYQDFLSRFSTDREPSPPMAAGD---SGDST---
MAQRGSSAPDVS-QATRSTL-CSPPRDSKA--G-LKSRSHPCTPV---------------
-GTPPLQNCEPIESKLRKQIQGCWRELLKECKEKDSDKQGSITAAEFLAIVEKFKLDISK
EESQQLIVKYDLKDNGKFAYCDFIQSCVLLLKAKETSLMRRMRIQNADKMKEAGAETQSF
YSALLRIQPKIVHCWRPM

PF13499 // ENSGT00390000013629_0_Domain_17 (1639, 1698)

RRTFKAYDENGTGLLSVADFRKVLRQYSINLSEEEFFHVLEY
YDKSLSSKISYNDFLRAFLQ----------------------------------------
---------------

----------------------------------MCKMAIIPDWLRSHPHT-RKFTHSRP
HSSLCRV-YSRNGSPN-----KFRSSS---TTAVANPTLSSL--DVKRILFQKITD

PF08976 // ENSGT00390000013629_0_Domain_0 (117, 182)

RGDE
LQKAFQLLDTGQNLTVSKSELRRIITDFLMPLTREQFQDVLAQIPLSISGTVPYLAFLSR
FG-GIDLYIN---GIKRGG--GNEMNCCRTLRELEIQVGEKVFKNIKTVMKAFELIDVNK
TGLVRPQELRRVLETFCLKLRDE-EYEK--------------------------------
-------FSKHYNIHNDTAVDYNVFLKNL-SINNDLNLRYCMGSQ---EVSLE-NQQAKN
SKKEHLLG-SASSEDIWRNYSLDEIERNFCLELSKSYEKVEKALSAGDPCKGGYVSFNYL
KIVLDTFVYQIPRRIFIQLMKRFGLKATTKINWKQFLTSFHEPQ----RLQVSSKDPLTK
RNS-IN---SRNESRKENIITKLFRHTEDRCASLKKALLII-NTKP

PF13833 // ENSGT00390000013629_0_Domain_4 (527, 578)

NGPITREEFRYILN
CVAVK-LSNSEFKELMQMLDPGDTGVVNTSMFIDL-IE-ENCRMRK--TSPYT-DAKTPF
LLAWDSVEEIVHDTITRNLQAFYNMLRSYDLGDTGLIGRNNFKKIMHVFCPFLTNAHFI-
-KLCSKIQDIGSGRILYKKLLAHIGIDGPPTVSPVLV--PKDQLLSEHLQKDE-QQQPDL
SERTKLTEDK--TTLTKKMTTEEVIEKFKKCIQQQHPAFKKRFLDFSKEPNGKINVRDFK
KVLEDTGMPMDDDQYALLTTKIGFEK-EGMSYLDFAAGFED-----PPMRGPETTPL-QP
PTPSKS--YVNSHFITAEECLKLFPR---RLKESFRDPYSAFFKTDADRDGIINMHDLHR
LLLHLLLNLKDDEFERFLGLLGLRLSVTLNFREFQNLCEKRPWRT-DEAPQRLIRPKQKV
ADSELACEQAHQYLVTKAKNRWSDLSKNFLETDNEGNGILRRRDIKNALYSFDIALTPRE
FEKLWARYDTEGKGHITY----QEFLQKLGINYSPAVHRPCA----EDYFNFMGHFTKPQ
QLREEMKELQQST-------EKAVADRDKLMDRHQDISKAFTKTDQSKTNYISICKMQEV
LEECGCSFTEEELTHLLN----SWGVSRHD-NTINYLDFLRAVEN-SKSTGAQP-KEKE-
---QSMPISFATLNPQEVVRKIQEVVEFFQLALSTAFSALDKEDTGFVKATEFGQVLKDF
CYKLTDNQYHYFLRKLRIHLTPYINWKYFLQNFSCFLEETADEWA---EKMPKGPPPTS-
PK

PF08976 // ENSGT00390000013629_0_Domain_11 (1323, 1444)

ATADRDILARLHKVVTS----HYHAITQEFENFDTMKTNTISREEFRAICNRHVQILT
D-------EQFDRLWNEMPVNAKGRLKYPDFLSRFSSETAATPMA-------TGDSA---
VAQRGSSVPDVS-EGTRSAL-SLPTQELRP--G-SKSQSHPCTPA----------STTVI
PGTLPLQNCDPIESRLRKRIQGCWRQLLKECKEKDVARQGDINASDFLALVEKFNLDISK
EECQQLIIKYDLKNNGKFAYCDFIQSCVLLLKAKESSLMHRMKIQNAHKMKEAGAETPSF
YSALLRIQPKIVHCWRPMRRTFKSYDETG

PF13833 // ENSGT00390000013629_0_Domain_17 (1650, 1698)

TGLLSVADFRTVLRQYSINLSEEEFFHILEY
YDKTLSSKISYNDFLRAFLQ----------------------------------------
---------------

----------------------------------MTRVVNAADYSTLYPQSHGIVINPRL
QPTSPRSSTSSSSSSSIQS----STKSRSTVGSVPDPTLSFP--DIEKILFQKAVAKEDE
LKRAFQTIDIDHTLKVTKGEFRRVIETFMLPLTQEQFDALLTKIPGSNKVCVPYLEFLSR
FAKPLDLISMKSR--------NIGENRTRTLSQLECLLREKLSKNMKHFIKTCRLFDYNQ
NGQIQRHELRRILEVNCFRMNDC-EYDK--------------------------------
-------LWNRYCFCRTNTLNYKEFLQYL-GLNLDKKKKRIMQSQDSDQKLND-ELSEKM
IPESKLPP-PMTPEYNLTKRHLDATAKSFREKLHSAYQNIVKAFRAYDVGRSGFVSLEYL
KSVLNTFVFPIRADVFQELMNRFGIKISKNMAWERFLDTFQEPL----IFDMSQASTTRK
QGRSRK---LDEDVASDRILIKLHEHIQDAYTSLKKAFLML-DTNHDGKITRNELRRILD
CIMFR-ISDDDFQELIKIIDPEHTGHLSYNMFLNLFQDKDALASSKMIGDSKKAKKPTSV
LEAWKIAEDVLTEQVKGYWNEFNKALQAFDPQNNGIVSRNNFRKVLQLYCPSLNDDHII-
-ALYQKYQDDTTEGVLYRMLLHSLGVADMPKELIVMSSS----PSSRGSQHREEKKQMDK
TERLKQIEDH-AYRYTKNRTVDEVIERLRDGILKQEASVRDAFLVYNKQASGKLSKTDFR
KI----------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------------T
ADADLACEQAHYYLSIKAQTRWNDLAVHFHEYDNEGNGIILKRELKDVLYKFCIPLNPKE
FEKLWARYDPSGKGYLTY----QEFLQKMGVDTTLPDTSFNKQFLTENYLRFMDHYKSVE
-RKHIDINE------------IINKIREKYHERSQDFHKAFLQQDKNREGSISVDDLRKM
LEDFNCYLGYEQYSELLY----SLGITIQD-NKLSYFDFLRVIDD-RAAFKRQKKKTVP-
---PVPPISFVQLSIDEAMRKIKQIVTESSDLLYKAFSAFDKERTGAISTLEFRQVLHHF
CFTLSEKQFSHLLKLQRLRGEHCVDWKYFLQKFNFLSETERE---------HS---KFA-
SRELSNQEVLARVQEVVGA----RFQAIEEEFKRADSAGEKVVSKEVFRDICNRRFL

PF08976 // ENSGT00390000013629_0_Domain_12 (1378, 1525)

LLT
D-------EQFENLWNTVPLDHNGKLKYPWFLRKFSLERREMSD---------TPVAAVT
PAEPGSRLCS------RPQTAASP-----PTAMKTSEPSRPH---------------TAA
VQTPPILNCQPIESKIRKVIQRRWREILKECKEKDVERLGEISVEDFLAIMEKANLNLTK
EELRQLATKYDFKSVGKFAYCDFLQSCVLLFKQQELSPLQRVVIQNPRLQGPLGPQSPTF
FNAMMRIQPQILHCWRPMRRTFKFHDESGTGQLSVQDFRQVLRKYGINLSEEEFFHILEY
YDKSLTSKISYNEFLRAFLQ----------------------------------------
---------------

----------------------------------MCKMAIIPDWLRSHPHM-RKFTHSRP
HSSPCRV-YSRNGSPN-----MFRSSS---TTAVANPTLSSL--DVKRILFQKITD

PF08976 // ENSGT00390000013629_0_Domain_0 (117, 182)

RGDE
LQKAFQLLDTGQNLTVSKSELRRIITDFLMPLTREQFQDVLAQIPLSTSGTVPYLAFLSR
F

ENSGT00390000013629_0_Linker_0_1 (182, 231)

G-GIDLYIN---GIKREG--GNEMDCCRTLRELEIQVGEKVFKNIKSVL

PF13202 // ENSGT00390000013629_0_Domain_1 (231, 253)

KAFQLIDVNK
TGLVQPQELRRVLETFCLKLRDE-EYEK--------------------------------
-------FSKHYNIHSDTAVDYNVFLKNL-SINNDLNLRYCIGNQ---VVSLE-NQQAKN
SKKERLLS-SASSEDTWRNYSLDEIERNFCLELSKSYEKIEKALSAGDPCKSGYVSFNYL
KIVLDTFIYQIPRRIFIQLMKRFGLKATTKINWKKFLTSFHEPR----GLEITNKGPLTK
RNS-IN---SRNESHKENIITKLFRHTEDRFTSLKKALLII-NTKP

PF13833 // ENSGT00390000013629_0_Domain_4 (527, 580)

NGPITREEFRHILN
CVAVK-LSDSEFKELMQTLDPGNTGVVNISVFIDL-VE-KNSRMRK--TSPCT-DTKTPF
LLAWDSVEEIVHDTITRNLHAFYNMLRTYDLGDTGLIGRNNFKKILHVFCPFLTNAHFI-
-KLCSKIQDIGSGRILYKKLLAHIGIDGPPTVSPVLV--PKDQLLSEHLRKDE-QQQPDL
SERTKPTENK--TTQIKKMTTEEVIEKFKNCIQQQDPEFKKRFLDFSKEPNGKINVHDFK
KVLEDTGMPMDDEQYALLTTKIGFEK-EGMSYLDFAAGFED-----PPMRGRETTPL-QP
PTPSKS--YVNSHFITAEECLKLFPR---RLKESFRDPYSAFF

PF13202 // ENSGT00390000013629_0_Domain_6 (884, 901)

KIDTDRDGIINMHDLHR
LLLHLLFNLKDDEFERFLGLLGLRLSVTLNFREFQNLCEKRSLKT-DEAPQRLIRPKQKV
ADSELACEQAHQYLVTKAKNRWSDLSKNFLETDNEGNGILRRRDIKNALYGFDIPLTPRE
FEKLWASYDTKGKGHITY----QEFLQKLGVNYSPAVHRPCA----EDYFNFMGHFTKPQ
QLQEEMKELQQST-------EKAVAARDKLADRYQDISKAFTKIDKSKTNYISICKMQKV
LEECGCSLTEGELTNLLN----SWGVSRHD-NSINYLDFLRAVEN-SKSTGAQP-KEKE-
---ESMPINFATLNPQEVVRKIQEVVESSHLALSTAFSALDKEDTGFVKATEFGQVLKDF
CYKLTDNQYHYFLRKLRIHLTPYINWKYFLQNFSCFLEETADEWA---EKMPQGPPPTS-
PKA

PF08976 // ENSGT00390000013629_0_Domain_11 (1324, 1444)

VASRDILARLQKAVTS----HYHAITQEFENFDTMKTNTISREEFRAVCNRNVQILT
D-------EQFDRLWNEMPVNAKGRLKYPDFLSRFSSERAATPTA-------TGDSA---
AAQRGGSVPDVS-EGIRSAL-SLPNQELRP--G-SKSQSHPCTPA----------STTAI
PGTLPLQNCDPIESRLRKRIQGCWRQLLKECKEKDVARQGDISASEFLALVEKFNLDINK
EECQQLIIKYDLKNNGKFAYCDFIQSCVLLLKAKESSLMQRMKIQNAHKMRDAGAETSSF
YSALLRIQPKIVHCWRPMRRTFKSYDEAG

PF13833 // ENSGT00390000013629_0_Domain_17 (1650, 1698)

TGLLSVADFRTVLRQYSINLSEEEFFHILEY
YDKTLSSKISYNDFLRAFLQ----------------------------------------
---------------

MWAPSRFPGTRGSF-----SKAEVIRSLLCHRTLMNKMMTVPDWHTLYVPT-RKAQCSRP
HSSPSSV-CPKNSVQS-----MLRPSSS--PSAAENPVLSFL--DIKRILFQKINDRKDE
LRKAFQLLDAGRSLTVTKGELKRVIGTFLLPLTREQFQDLLAQIPLTGSGNVPYLEFLSK
FG-GSDLNIN---VIKRGG--GHEMDSCRTLKELEIQIGEKVFRNPKAVIKAFRLLDVSS
TGRVQPQQLRRVLETFCLQMTEE-EYQK--------------------------------
-------FSKHYGIDKDTAVDYGVFLKNL-SKSNDVHLRYFMGNQ---EVSPE-NPQART
LKREHWLS-STPSEESWGGYSLDDIEKAFCREFSKSIDKIEKALSAGDPSRGGYVSLNYL
KVVLDTFVCRLPRRLFLQLMKRFGFKTTARINWKQFLTSYYELQ----GLEASNTVPPLK
RDS-TH---SRSRSRRENAVTKLLRRAEASSEPLRKALLMSSSTK

PF13833 // ENSGT00390000013629_0_Domain_4 (526, 578)

PGGRMTGDELRQILS
ATLVK-VSDSEFRELMRTLDPEATGVVTAGSFLDL-LE-ASPKTRK--TSPCT-GAKTPL
PLAWVSVEAMVHDAIAKNLQAFCNMLQSYDLRDTGLMAQSNFKAVMHVFCPFLTHKHLK-
-KLCCKFQDPTSEKILYKKLLACIRVSGSPTVS------PKDQP-CGHFQKEE-G---QF
SGRTKPTRDR--TPTIKNMTRDEAIENLKSRIKRQDPVFRKRFLEVSGGLLGKIGLRDFK
KVLEDSGMPMDEVQYSLLATKIGFRK-EGMSYLDFAVGFEG-----TGGHTPPRTCP-A-
-GASRL--SLIGHFVTAEECLKLFPK---RLRESFRDPYSAFF

PF13202 // ENSGT00390000013629_0_Domain_6 (884, 901)

KIDTDRDGIISMRDLHR
LLQQLLFNLKDEEFERLLGLLGLRLSVTLNFREFQSLCEKGPSPM-DEAPQRLLRPKQKV
ADSELACEQAHQYLVIKAKTRWTDLSKNFIETDTEGNGILRRRDIKNALYGFDIPLTPRE
FEKLWQSYDTEGRGYITY----QEFLQKLGINYSPTVHRPYA----EDYFNFLGHFTKPQ
QVQEEIQELQQSTER----AKPARWA--------------------------WESRRSQV
LQECGCPLQEEELAALLN----SLGIICHD-NTINYLDFLRALES-SKAARPQR-EEKE-
---DAVPINFSTLNPEEVVKSVQEVVSTSQQALSQAFSALDKEDTGFVKATDFGQVLKDF
CHKLTDSQYHLFLRKLRIHLTPSIHWKYFLETFGCFLEEAADEWA---ERMPRVPPPTS-
PREA

PF08976 // ENSGT00390000013629_0_Domain_11 (1325, 1441)

AIAELLARLQKAVTT----HHYAFAQEFKNFDTNKSNTVSRDEFRAVCTHHLQILT
D-------KQFDRLWGEMPVTARGRLKYQEFLSRFGVEQVASPPA-------TGDSV---
QAQKGSSVPQVS-NRTQSAI-SSPTRDLRA--E-LKSRSHPCTPA---------------
-GDLPLQNCEPVESRLRKQVQGCWRALLKDCKEKDLARLGTIAAPDFLALVQQFRLDLSK
EESQQLLTKYDLKNNGTFAYCDFIQNCVLLLRATETSLMRRLKIQNTHKMKEAGAESCSF
YAALLRIQPKILHCWRPMRRMFKAYDQGG

PF13833 // ENSGT00390000013629_0_Domain_17 (1650, 1698)

TGILSADDFRKVLRQFSINLSEEEFFHLLEY
YDKTLSSKVSYNDFLRAFLQ----------------------------------------
---------------

----------------------------QHGRLR----MEPSAPASAYAAI-WALPGCPI
HSLPCLL-CT---FLI-----NCCIPFT--ASAAANPVLSFL--DVKRILFQK

PF08976 // ENSGT00390000013629_0_Domain_0 (114, 184)

ITDKKDE
LRKAFQLLDTGQDLTVTRSELKRVIATFLLPLTREQFQDVLAQIPLSSSGSIPYLEFLSR
FG-GTDLNIN---VIKRGV--GNETDSCRTLKELELQ----VFRNLKTVMKAFQLVDVNR
RGLVQPQELRRVLDTFCLRMTEE-EYRK--------------------------------
-------FSKRYNIDRDTAVDYSMFLKNL-SKSNDLHLRYFMANQ---EVSAE-NQQART
FKREPLLN-YVSSEEGGSSYSLDDIERTFCQEFSKSIDKIEKALSAGDPSRGGYVSLNYL
KIVLDTFVYRLPRKIFLQLMKRFGFKTTTRINWKQFLTSFYELQ----GSLLTG------
----IN---TQAQSQKENVITKLLRHTEYGFVALKKALLMPGSSTPAVRSWASGLGRLFE
CSCLH-SSH---------------------AF---------LERFT-KTSPCP-GAKTLL
PLAWESVEEMVHEAIAKNRQAFSNMLQSYDRRDTGTIARNNFKKVMRIFCPFLANEHLI-
-KLCCKFQDTTSEKILYRKFLACIKVCAPSTVSPILT--SKDQP-CERFQKE--QQQPAL
SERTEPTSDG--TATAKNMSIDEVIEKLKSCVRRQDPAFRKRFLAVSQGLHRKIGVRGFR
KVLEDSRMPMDETQYLLLATKIGYKK-EGMSYLDFVERFED-----TKTSGPAATPP-QT
PISSKN--YLNNHFITAEECLKLFPK---RLKELFRDPYSAFFKIDTDRDGIINMRDLHR
LLQRLLFNLKDEEFERLLGLLGLRLSVTLNFREFQNLCEKGPPQM-DDAPQRLIRPKQKV
ADSELACEQAHQYLVIKAKNRWADLSKNFIETDSKGNGILRRRDIKNALYGFDIPLTPRE
FEKLWQSYDTEGRGHITY----QEFLEKLGINYSPAVHRPYA----EDYFNFLGHFTKPQ
QMQEEIQELQQSTER--------------LVEHFQDISKALGTLDTSQSGSVSLSKMQQV
LQECSCPLKEEELTDLLN----SLGIICHD-NTINYLDFLRALEN-SKAARPQP-KEKE-
---EAMPTNFSTLSLEAVVRHIQEVVSTAQLALVQAFSALDKEDTGFVKATDFGQVLKDF
CYKLTDSQYHYFLRKLRIHLTPYIHWKYFLENFGCFLEETADEWA---EKMPRIPPSTS-
PRE

PF08976 // ENSGT00390000013629_0_Domain_11 (1324, 1442)

VASRELLACLHKAVGS----HHHAFAQEFENFDTNKTNTVSRDEFRAICTRHLQILT
D-------EQFDRLWSEMPVSTKGRLKYQEFLSRFSVEQAATPPA-------TGDST---
QAQKGSSIPEVS-EETRPAG-SSPMRDPRA--G-LKSRSHPCTPA---------------
-GTPLLQNCEPIESRLRKQIQGCWRELLKDCKDKDTGRLGTVPAAEFLALVEKFHLEVSK
EEGQQLLTKYDLKDNGTFAYCDFIQSCVLLLKAKETSLMQRMRIQNAHKMKEAGAETSSF
YAALLRIQPKILHCWRP

PF13499 // ENSGT00390000013629_0_Domain_17 (1638, 1698)

MRRMFKAYDEGGTGFLTADDFRKVLRQFSINLSEEEFFHLLEY
YDKTLSSKVSYNDFLRAFLQ----------------------------------------
---------------

----------------------------------MYKMSVLPEWHSLYLNT-RKLPCARP
HSSPCRT-Q-RPIVHD-----LCRPFSS--TTALANPVLSSL--DVERI

PF08976 // ENSGT00390000013629_0_Domain_0 (110, 182)

LSQKISSKRDE
IKKVFQILDPNHSQTVTKGELKRTITAFLMPLTKDQFQDLLAQIPITSLGNVPYLEFLSR
F

ENSGT00390000013629_0_Linker_0_1 (182, 229)

G-GIDININ---GIKRVN--ENEVDNGQTLKEI--QLTEKIFRNMRT

PF13202 // ENSGT00390000013629_0_Domain_1 (229, 253)

IRKVFQLIDVNN
TGTVQPQELRRVLETFCLKMKDE-DYEM--------------------------------
-------FSKQYNINSTTAVDYNAFLKNL-SVKNETNFKHLLSNP---EPSKE-NQQGKI
AK--RLTD-ATSSEDIWKNYSLDDLEKTFCQELVKSYEKIEKALSAGDPSKGGYISLNYL
KVVLDTFTYRLPRRTFIQLMRRFGLKTTTKVNWKQFLTAVYERQ----GWEVSKTIPLKK
RSS-TE---ARNRFRKENIIKKLFKYSEERYTALKKALLII-SPTPSGHVTWEDLRHVLN
CVVVK-LSDSEFNELKQTFDPEGTGTVKISSLLDV-LD-DSPKVRK--MSPST-DTKTPL
PVAWDSVEELVLDALTRNHQAFYGMLQSYDLGDTGSITKNNFKKVMRVFCPYLSNEHLA-
-KLSNKFQEVGSGKILYKRYLFSIGLGIPPPGSRLSS--PKSQR-SEQFQIE----QQ--
DERTQPLRDK--TTEIKNMTKEEVIDSLKRRIQQKDSVFRQEFLNISKDPDVKISQGEFR
KVLERSGMPMNDCQYAMLASKLGFKNEDGMSYQDFTMGFED-----SMLSGLETVPL-QS
RPTSKM--NLDEHFVSAEECLRIFPK---KLKDSFRDSYAA

PF13202 // ENSGT00390000013629_0_Domain_6 (882, 901)

FFRIDTDRDGIISMHDLHR
LLQYLLINMMDFEFERFLSLMGLRLSVTLNFREFQNLCEKRPWKS-DEAPQRLIRCKQKV
ADSELACEQAHQYLIMKAKTRWADLSKNFIETDNEGNGILRRRDIKNSLYGFDIPLTPRE
FEKLWQNYDTEGRGYITY----QEFLHRLGIRYSPKVHRPYK----EDYFNFLGHFTKPK
QVQEEIQELHQISER------------EKLLDHFEEISKALNAMEKSR--PVALGRVQKV
LQECGCPLKEEELIIILK----SLDVSVHN-NQIDPVEFLRALEI-SWASKPHP-KEK--
EESS--PINFSKLNPDEVIKSMQEVVESSQPALVKAFSALDKEDTGFVKAMEFGDVLKSI
CQKLTDNQYHYFLRRLRLHLTANIHWKYFLENFSSFLDETADEWA---ENMPKVPPPEC-
PK

PF08976 // ENSGT00390000013629_0_Domain_11 (1323, 1444)

ETSSREILARVQKAVTS----HYHTIAQEFENFDTLKSNTVSRDEFRSICTRHVQILT
D-------EQFDRLWSEMPVNAKGRLKYQDFLSKLSTERVPSPPMAAGD---SGDSM---
VAQRGSSAPEVS-QGARSTL-SSPSRDLRA--G-LKSRSHPCTPV---------------
-GTPPLQNCEPIESRLRKQIQGCWRELLKECKEKDTDKQGSITAAEFLALIEKFKLDISR
EESQQLLVKYDMKNNGKFAYCDFIQSCVLLLKAKETSLMRRMRIQNADKMKEAGVETPSF
YSALLRIQPKIVHCWRPM

PF13499 // ENSGT00390000013629_0_Domain_17 (1639, 1698)

RRTFKTYDENGTGLLSVADFRKVLRQFSINLSEEEFFHVLEY
YDKSLSSKISYNDFLRAFLQ----------------------------------------
---------------

----------------------------------MCKMSVIPDWHPVHFHK-QKLRSLRP
YSSPCGV-FSKSGLPA-----AFRPCSS--GTGVANPVLSTL--DIRRILFQKITDKGD

PF00036 // ENSGT00390000013629_0_Domain_0 (120, 148)

E
LKKAFQLLDPSQSLTVSRNELRRLITDFLMPLTREQFQDVLAQXXXXXXXXXXXXXXXX-
---XXXXXXX---XXXXXX--XQETTCCRTLKELEAQLGEKVFKNIK

PF00036 // ENSGT00390000013629_0_Domain_1 (228, 256)

SIIKAFKLIDVNH
TGLVQPHELRRVLETFCMKIADG-EYTK--------------------------------
-------FSRRYNLDQDAPVDYSGFLKNL-SVNNDLNLRYLTGSP---EIL-G-EQKTRN
PKTEHPFS-PVSSEADWSNCSLEEIEKTFCQELSKSYEKIEKALSAGDPSKGGYVSLNYL
KIVLDTFVYQLPRRIFIQLMKRFGLKTTSKINWKQFLTSFNEPR----GLEGNNVVPVAK
KNG-VC---SRSQGHKEPNIVKLLRLAEDHCGALRKVLQAM-KKKSDRQVTREELRHMLN
CTVVK-LNDS

PF00036 // ENSGT00390000013629_0_Domain_4 (551, 581)

EFRELMQVLDPRGSGMVSVSRFTEL-LE-EKPMMKK--LSPAS-DTMTPP
PLAWDSVEEIVHDALARNLPAFYKMLQSYDLADTGLIGRNNFKKVMQIFCPFLTNEHII-
-KLSSRFQETGSGRVFYKKLLQNLDLHSPPSGSPALT--PQAQPLSRGPPDGEVQQSLDA
PKRTRPAEDE--SSRSRYLTKEEAIEKLRCCIQERDPTFRRHFLDVSKEPHRKISLREFK
KVLEDSGMPMTEEQYALLAAKIGYRK-EGMSYMDFTAGFED-----AAVPGPKSLLA-QT
PTPAHT--PPSNHFVTAEECLQLFPK---RLAESFQ

PF00036 // ENSGT00390000013629_0_Domain_6 (877, 905)

DSYSAFFKMDTDRDGIISMHDLQR
LLLHLLFNLKDTEFERFLGLLGLRLGVTLNFREFRGLFEQTPLQT-DEAPQRFTXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXYDTEGRGHITY----QEFLQKLGVAYSPAIHRPFA----EDYFNFMGHFTKPQ
QVQEEMRELQQXXXX-------XXXXXEKLLAHSEDISKALAQEEKSRSGSISMCRLQKV
LRECGCPLKEEELASLLD----SWGVSWQD-RSINHADFLGALESSKLRPEPPP-MEKG-
---QGEPPDFSTVALSDVVRNIQEVVGASQA

PF00036 // ENSGT00390000013629_0_Domain_10 (1232, 1260)

ALSQAFAALDAEDTGFLKAMEFGDVLKGF
CPKLTDSQYHYLLRKLRLHLTPHIHWKYFLENFGSFLEETADEWA---EKMPKGPLPPV-
PRDPSIRETLVRLHKAVAA----CIHAITQEFENFDTMKTSTVSRDEFRAVCTRH

PF08976 // ENSGT00390000013629_0_Domain_12 (1376, 1525)

IQILT
D-------EQFDRLWSEMPVNAKGRLKYLDFLNRFSSEQVSTPAA-------TGDST---
RAQRGSSVPESW-EETGVAA-SSPTRDPRA--G-VRSQCHSGXXX----------XXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLADSFGLDLST
EESHQLLLKYDLHGHGRFAYPAFLQSCVLLLQAKETSLLQRLRIQNAHKMKEAGAETASF
YSALLRIQPQILHCWR

PF00036 // ENSGT00390000013629_0_Domain_16 (1637, 1665)

PMRRTFKAYDESGSGLLSVADFRKVLRQYSINLSEEEFFHILEY
YDKALSSKISYNDFLRAFLQ----------------------------------------
---------------

----------------------------------KCKMAIIPDWLTSYPHT-RKFTCSRP
HSSPCRL-YSRNGFQN-----MFRPSSS--TTAVANPILSFL--DVKRILFQKITDKGDE
LKKAFQLLDPGQNLTVSKNELRRTIATFLMPLTKEQFQDVLAQIPLTCSGSVPYLEFLSR
FG-GIDLNVN---VIKKGG--GNEINCCRTVKELELQMGEKVFKNIKTVI

PF13202 // ENSGT00390000013629_0_Domain_1 (231, 253)

KAFKLIDVNK
TGLVQPHELRRVLETFCLKLRDE-EYS---------------------------------
-------------------------------------------------VSLE-HQQGKN
SRKERSLN-SVSSEDNWKNYSLDEIERTFCQEFWKSYDKIEKALSAGDPSKSGYVSFNYL
KIVFDTFVYQLPRRVFIQLMKRFGLKTTTKINWKQFLTSFYEPQ----GLDISNIVPPRK
RNS-FS---CRNQSRKEDIITKLFRHSEDCFTSLKKALLMI-NTE

PF13833 // ENSGT00390000013629_0_Domain_4 (526, 578)

PDGQITGEELRHVLN
SMVAK-LSDSEFKELMQMLDPGGTGMIKISMFTDL-LD-ENPKTRK--ISPCT-DTKTPL
HLAWDSVEEVVHDAITRSLQAFYNMLQSYDLGDTGLIGRNNFKRIMNIFCPLLMNEHLV-
-KLCSKFQDNASGRILYKKLLASIGINGPPVVSPILA--PKDQL-SERFQKAK-QQQPDL
SERTKPTEDK--TTLTKNMTKEEVIKKLKNYIRQQDPAFRKRFLDFGKEPNGKINVLEFK
KVLEDTGMPMDDDQYALLTTKIGFKK-EGMSYLDFATGFED-----AQRNKPEAAPP-QT
PISSKS--HLDSHFITAEECLKLFPR---RLKESFRDSYSAFFKT

PF13202 // ENSGT00390000013629_0_Domain_6 (886, 902)

DTDRDGIINMQDLQR
LLLHLLLNLRDEEFERFLGLLGLRLSVTLNFREFQNLCEKRPIRT-DDAPQRLVRPKQKV
ADSELACEQAHQYLVTKAKNRWSDLSKNFIETDNEGNGILRRRDIKNALYGFDIPLTPRE
FEKLWTSYDTEGKGHITY----QEFLQKLGINYSAAVHRPYA----EDYFNFMGHFTKPQ
QVQEEIKELQQNSEK-------AVPARDKLMDHYQDISKALTKIDKSKNGYISIRKMQKV
LQECGCSLMEEELTNLL----SSWGISWHD-NSVSYADFLRALEN-SMLARAQP-KEKE-
---ESLPINFSTLTPEEVVKNIQEVVESSQPALLKACSALDKEDTGFIKSTEFGQVIKDF
CYKLTDSQYHYFLRKLRIHLTPYINWKYFLQNFSCFLEE---------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------

------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------SPLTSSGAVPYLEFLSK
FG-GVDLNVN---VTKRAS--ENDMGQSRTLNELEAQLGDKVSKNSKNPAKALRLPDVNK
TGLLQPWELRRVLETFGLRMGED-EYTR--------------------------------
-------FSSHYNVDKS-EVDYKALLKNL-SINTDINSRYSVGNP--XXXXXXXXXXXXX
XXX-XXX--XXXXXXXXXXXXXXXXXXXXXXXIRKSYERLEKSLSAGDTTHSGFVSLNYL
KTVLDTFVCRLPRRPFLQLMKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXF
NSCISN---SRNQPYKENVITKLARQAEDRS-ALEKAFLEA-SSKHEGRITWKELQRILN
SXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXX-XXXXXXXIRK--RSPLTSTKANPL
SLAWNSVEEMVCGGILRDGPAFYQMVRSYDCGDTGFLSQTTFKKIISTVCPFLTGEHLR-
-QLCSKFQDIASGRICYKKLMASLGGHSWCISSPVAT--PAGPPPSECVPKED-PQRPDL
PKXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XVLEMNGMWMDNEQFALLTTKIGFRK-EGMSYLDFAARFQDVD-----MSRPPLPCP---
----ALRTRLSSPFASAEECLKHFSL---RLKESFQNPYS

PF00036 // ENSGT00390000013629_0_Domain_6 (881, 905)

VFFKIDKDRDGVISMQDLYG
LLAHLQFNLKQEEFVRFLELLGLRLSVTLNFREFRHLCEKGTHRA-DEAPQRLIXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXNFIETDSEGRGILRRRDIKNALYGFDIPLTPRE
FEKLWL-YDTEGRGHITY----QEFLQKLGINYQPTVHRPYA----EDYFNFMGHFTKPK
QIQEELKELQRDTHQ----AIXXXXXXXXXXXXXXXXXXXXX---X------XXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXWGVSCQN-DSVNYLDFLKAVDP-SKAARPQP-GEKE-
---ESKPVNFAALPLEEVLKKVQEMVDSSQE

PF00036 // ENSGT00390000013629_0_Domain_10 (1232, 1260)

AMSKAFSELDQGDTGFVTAAEFGQVLKGI
SCNLSDSQYHYFLRKVRLHLRPHINWKYFLQNFCSFLEEXXXXXXXXXXXXXXXXXXXX-
--XXXXXXXXX-XXXXXXX----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
X-------XXFDKLWGEMPVTAKGKLKYQDFLSRFSCEKAVSPPI-------SREST---
RAQKGSSLPEVS-EGGRSTR-SSPLHAPKV--GTPKTWSHPCXXX----------XXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVLRQYSINLSEEEFFHILEY
YDKTLSSKISYNDFLRAFLQ----------------------------------------
---------------

----------------------------------TCKMAVVPDWHTLYPHT-QKFTHFRP
RSSPCRV-YSRNGFQN-----VFRPSSS---TAVAHPILSSL--DVKRILFQKITDKGD

PF00036 // ENSGT00390000013629_0_Domain_0 (120, 148)

E
LKKAFHLLDISNNMTVTKNELRRVITTFLLPLTREQFQDVLAQIPLTSSDALPYLVFLSR
FG-GIDLNIN---VIQRGG--ESEMNCCRTLKELEVQVGEKIFKNIKTVIKALKLIDVNK
TGLVQPHALRRVLETFCLKMKDD-EYKK--------------------------------
-------FAKHYNIDKDTAVDYNVVLKNL-STNNDLNLKYSMRSQ---EVPWE-DQRVKS
SKRDYLPS-PVSSEDIWKNCSLDEIERTFCQEXXXXXXXXXXXXXXXXXXXXXXXSLNYI
K-VLDTFVYRLPRRIFIQLMKAPPG-----------------------------------
----------------------------------------K-NSKPDGHIT-EELRHILN
CMVVK-ISDSEFKELVQTLDPGCTGWVNVSTFIEL-LE-ENPKLST--TSSCK-DTKAPL
FLAWDSVEEIVHDSISRNLHVFYNMLRSHDLGDTGLIGRNNVKKIMHVFCPFLTTEHLV-
-KLCNKFQDIASGRILYKKLLACLGINGPPTVSPVPV--PKDQLLNEHLQKGE-RQQPDL
SETAKPTESK--SAVTENMTKDVLIEKLKNCIRQPYGAFR-KFLDFSKEPNGKMNVHDFK
KVLEDNGMPMDDDQYALLTAKLGYKK-EGMSYLDFATGFEA-------------------
PVLSKG--NLDGYFITAEECLRQFPR---RLKESFRDPYAAFFKMDTDRDGIVTMHDLHQ
L-QHLLFNLKDEDFERFLGLLGLRLSVTLNFHEFRNLCEKRPFRIEDAAPQRFIXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXNFIETXXEGNGILRRRDAKNALYVFDIPLTPRE
CEKL-MRYDTEGRGHITY----QEVLQKLGVNYSAAIHQPYV----EDYFNFMGHFTKPQ
QVQEEMKE--QSMER-------AVPAGDKLKDHYQ

PF00036 // ENSGT00390000013629_0_Domain_9 (1116, 1144)

DISKALTKLDKSKNGYISLCKMQKL
LQE

ENSGT00390000013629_0_Linker_9_10 (1144, 1232)

CSCSLKAEELADRLTXXXXXXXXXXXXX------XXXXXXXXXXXXXXPQH-KEKE-
---ESVPINFAALSPEEVLKNVQEVVASSSP

PF00036 // ENSGT00390000013629_0_Domain_10 (1232, 1260)

ALSTAFSALDKEDTGFVKASDFGQVLKD

ENSGT00390000013629_0_Linker_10_11 (1260, 1347)

F
CYKLTDTQYHYFLRKLRIHLTPYINWKYFLQNFNSYLEEAAAEWA---EKMPKGPPPVS-
PKKMANQEVLARLHKAVTF----HYN

PF00036 // ENSGT00390000013629_0_Domain_11 (1347, 1375)

TIAQEFENFDTMRTNTVSRDEFRSICTR

ENSGT00390000013629_0_Linker_11_12 (1375, 1376)

H

PF08976 // ENSGT00390000013629_0_Domain_12 (1376, 1525)

VQVLT
D-------EQFDRLWDQMPVDAKGRLQYLDFLRSFSSEKAAPPPA-------PGASA---
KAQRGCGVPEVS-ERSRSAGLS-PTRDLKA--G-SKPRSHPCTPA----------S----
-TTPPLQNCEPVENKLRKKIQGCWREFLRECQKRDANKQGEIPATEFQALVEEFNLDVNR
DECRQLIVKYDLKNNGRFAYCNFIQSYVLLLKAKETSLMQRMKLQKATKMKECGAETSSF
YAALLRIQPQIVRCWRPMLRTLKAYDEGRTGLLSVADFRMVLRQYGINLSEEEFFHILEY
YDKTLSSKISYNDFLHAFLQ----------------------------------------
---------------

--------MKGGE----------RK-----SREVIRTVVNSVDLGNLNSSTTGIKADVRP
HSSPLGI-TTPNTGRN-----LVKSSSS---ISVVNPVLSFA--DLDRIFFQKILKKEDE
LKKAFSIIDSEQTLRVTKSQLRRIIEVYLLPLTRKQFNEVLSQIPLTSNGEVPYLEFLAR
FG-RLITNVN---SLKRTP---GKQFTSKSLNQLECMLGEKIFKNVKSITKAFKLFDCTQ
SGQIHPSGLRQVLENYCFKMRDE-EFEK--------------------------------
-------LWNRYSLGKDTALDYNAFLKNL-AMNINLNQKYNFVSK---GLSQ--KQQAES
PDSKYVFSFSSTSGDGWENSSMDEIEAAFCKEFGVSTANIEKALSAFDTTKRGYVSLNYL
KVVVDNFIFPLPKGIFLQLLKRLGFKTTGKIAWKQFLRKCQDCA----LAENGNMIPMRK
KKR-VC---GSEPVFKESILVKLCRLVDDNFFALKKAFHTI-NPKQDGKITGKEMRHILS
TVLWK-VSDSEYKELMQILDPTGSGYINYITLLYL-LEEDSSMMKKKRPNGLK-DEKAPQ
FLAWDSVEEVLQDAISKNLQDFHVLLKTHDIGDTGLISRNHLKKILQTFCRYLTDEHLT-
-KLCDKFQDVTSGGILYKKLLASIGIMSPIQ--DSIVTIQSFQSPNGS-------RRDDT
SDRSKHSDYK--NEPVRNKSLEEVIESLKNWIQQQDTSFRDTFLEYSRHPLEKISKEEFR
KVLEDNGMPMDDEQFGLLVKKIGYKN-EGLSYLDFASGFEASDA---KPNGLESPGTPAV
PASLTPKTSFESHFTSAEECLKIFPK---KIKEIYGDAYSAFYKTDTNHDGIINMSDFRT
LLHHMLITLKDEEFLRLLDAMNLKPGLTLNYREFRNLCEKKQFRK-DDPPQRLIRPKPKT
TDSELACDQAHNYLVSEAKNRWFDLSKNFLETDSEGNGILRRKDIRNALFGFDIPITPRE
FEKLWARYDTTQKGYVTY----QEFLSRLGIEYSPSIHRPYA----IEHFNFMGHFTKPE
QIMEETKELQQYMEM-------NKPFKDKLKDHYQDINQAMGKLDKHKSSVISLNELHKL
LQEYHPNITEEEITAMLK----SLGIAYND-NLIYYHDFLKALEN-LKPIKSHS-REKE-
---EPQPISFSALTPEQALKKMKEMVTMNCHAFCKAFSACDKEDTGIIKASDFAQVIKDL
CPKLKDSQYSYVLKKLRLHLNTHINWKFFLRNFPCFFEETAAEWT---EKMQRASRPKS-
PKDQFLKEILMRIRDVVTT----RYLNISQEFSDIDCCKSNLVNREDFRIVCNRHF

PF08976 // ENSGT00390000013629_0_Domain_12 (1377, 1525)

QVLS
D-------EQFESLWNELPLNSEGRLKYQEFLNKFNMEKTLSPPASVESLKRSGGTTPEA
EAAQQGPAPAA---GGSSAP----GSASR-----PQTIHAPGTAS----------STASR
AWVPPLQNLEVIETKLRKKMQGFWKEMLKECKEKDVDKQGEITVADFQALVDKYNLDISK
EECQHLITKYDLKNNGKFAYCDFFQSCVLLLKPKETSLMQRMKIQQVYMMKGAGTQSASF
YAALLRIQPKILHCWRPMRRTFKSYDESGTGLLSIADFRKVLRQYGINLSEEEFFHILEY
YDKTLSSKISYNDFLRAFLQ----------------------------------------
---------------

--------MKRSGVRLNAAKVNSTRSCSTKARDLMRKMAILPDWHSLYPTT-RKM-YSRP
HSSPVRV-HSRTGCQD-----LGRPSSS--TTPVANPVLSFL--DVERILSQKLSNKRDE
MKKVFQVLDSTHSQTLTKGDLKRAITAFLMPLTREQFQDLLAQIPLTSSGNVPYLEFLSR
FG-GIDLNID---IIKRGN--GDKIDHSRTFKELE------VFRNMKT

PF13202 // ENSGT00390000013629_0_Domain_1 (229, 253)

MRKVLQLIDVNN
TGTVQSRELRRVLETFCLRMRDE-EYEM--------------------------------
-------FLKEYNIGG-IMVDYNAFLKNL-SISSNLNFKYPQSGS---ELPRE-NQQAKT
ARRERPLN-SMPSEDVWKSYSLDDLEKTFCQELSKSYEKIEKALSAGDPSKGGYVSLNYL
KVVLDTFVYRLPRKIFIQLMKRFGLKTTTKVNWKQFLTAFYERQ----GLEVSKPTPQKK
RSS-TD---SRNQSRKENVIKKLFKYSEERYTALKKSLLII-STTPSGHIAWDELRHVLN
CMVAK-LSDLEFNELKQTFDPEGTGVVKISSLLDA-LD-DSPKVRK--MSPST-ETKAPP
PVAWNSVEEMVLDTITRNLQAFYGMLQSYDLGDTGTIARNNFKKVINIFCPYLSNEHFV-
-KLSSKFQDTASGRILYKKFLLSIGVNIPPPILPLSV--PKDQL-SEKLQCEE-QGQPDL
PERTQPTRDK--TTEAKNMTKEEVIDRLKHCIQQQDPVFKEQFLSISKEPDVKIGLEDFR
KVLEESGMPMNDNQYAMLASKIGYKK-EGMSYQDFTSGFED-----TKPSGQETNPL-QP
RTASKT--NLDEHFIPAEECQKLFTK---KLKESFRDPYSAFFKVDTDRDGIINMHDLHR
LLQQLQLNMKDCEYERFLSLLGLRLSVTLNFREFQNLCEKRPWRA-DEAPQRLIRYKQKV
ADSELACEQAHQYLVIKAKTRWADLSKNFIETDNEGNGILRRRDIKNALYGFDIPLTPRE
FEKLWQNYDTEGRGYITY----QEFLERLGIRYSPKVHRPYK----EDYFNFLGHFTKPK
QIQEEIQELQQMTER------------EKLMEHYEEISKALNMLEKSKMGSAALSKVQNV
LQECGCSLKEEELISLLK----SLGISVHN-NCINPLDFLRALEI-SKTSKAQP-KERE-
--ECSPRSNFSKLNPEEVVKSMQAVVESSQPALLKAFSALDKEDTGFVKAMDFGDVLKSF
CQKLTDNQYHYFLRKLRLHLTPTIHWKYFLENFGSFLEETADEWA---EKMPKISPPTS-
PKE

PF08976 // ENSGT00390000013629_0_Domain_11 (1324, 1444)

VAKKDILARVHKAVAS----HYHAIAQEFENFDTMKSNTVSRDEFRSVCTRHVQILT
D-------EQFDRLWSEMPVNAKGRLKYQDFLSRFSTERAPSPPMAAGDFGDSGDST---
VAQRGSSAPEVS-QGTRSTL-YSP-RGPRT--G-LKSRSYPSTPA---------------
-GTPPLQNCEPIESKLRKQIQGCWRELLKECKEKDSDKQGSVTAAEFLALVEKFKLDISK
EESQQLLVKYDLKNNGKFAYCDFIQSCVLLLKAKETSLMRRMRIQNADKMKEAGVETQSF
YSALLRIQPKIVHCWRPM

PF13499 // ENSGT00390000013629_0_Domain_17 (1639, 1698)

RRTFKTYDENGTGLLSVADFRKVLRQYSINLSEEEFFHVLEY
YDKSLSSKISYNDFLRAFLQ----------------------------------------
---------------

----------------------------------MCKMATSPDWHNLYPHT-RKFTYSRP
HSSPCRV-YSRNGYQN-----MFRPSSS--ATAIANPILSFL--DVKRILF-KITDQKDE
LKK-FQLLDTDRHTVKSLR-----TITLLMPLTXXXXXXXXXXXXXXXXXXXXXXXX-XX
XXXXXXXXXX---XXXXXX--XNEMNCCRPIKE---EVVGKVFKNMK

PF00036 // ENSGT00390000013629_0_Domain_1 (228, 256)

TVIKALRLIDVNK
TGLVRPHELRRVLETFCLKMRDE-EYQQ--------------------------------
-------FAKHYNIDKDTSVDYNVFLKNL-SINNNLNLRYVMGNQ--XXXXXX-XXXXXX
XXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXLSKSYK-IEK-LS-AGPWKGGYYD-NYL
K-IVDTFVYRLPR-IFIQLMKGFGLKTTAKINWKQFLTSFHEPR----ELEVSILVPPTK
RNXXXX---XXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXKPDGEVTREELWHILS
RMAVK-LSDSEFKELLGALDPGSTGVVKVSTLIDL-LE-DTPKASK--VSPCV-DPKTPL
LLAWDSVEETVHDAILRNLQAFYRMLQSYDLGDTGLIGRKSFKKIMLTFCPSLTNEHII-
-KLCSRFHDTTSGRIFYKKLLACIGVNGPPPVSPILV--PKDQLLSEHFHTEK-QPPPEL
SEXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSP
KVLEDSGMPMDDHQLALLAAKIGYKE-EGMSYLDFATGFED-----PAPSGPEATPP-PT
PAPSKS--HLNSHFITAEECLALFPG---RVKESFQXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPKQKV
ADSELACEQAHEYLVTKAKNRWADLSKNFIETDNEGNGILRRRDIKNALYGFDIPLTPR

PF00036 // ENSGT00390000013629_0_Domain_8 (1020, 1047)

E
FEKLWTRYDTEGRGHITY----QEFLEKLGISYSPAVHRPCA----EDYFNFMGHFTKPQ
QIQEEIRELQQGTEK------AAVPARDKLIDHYEEISKELGKLDKSKGGYVSVCRVRNV
LQECGCPLEEEELTGLLH----SWGISWHD-NSINSLEFLRAIEN-SKPDRPQP-KEKE-
---ERLPISFSALTPEEIVKKVQEVVDSSRP

PF00036 // ENSGT00390000013629_0_Domain_10 (1232, 1260)

ALLKAFSALDKEDTGFVKATEFGQVLKD

ENSGT00390000013629_0_Linker_10_11 (1260, 1347)

F
CCRLTDNQYHYFLRKLRIHLTPYIHWKYFLQNFGGFLEETADEWA---EKMPKGPPPRL-
SKEMADKDILARLHRAVAS----HYQ

PF00036 // ENSGT00390000013629_0_Domain_11 (1347, 1375)

AIAQEFENFDTMKTNTVSRDEFRAICTR

ENSGT00390000013629_0_Linker_11_12 (1375, 1376)

Y

PF08976 // ENSGT00390000013629_0_Domain_12 (1376, 1525)

VQILT
D-------EQFDRLSE---VVNKGKLKYQDLLSRFSTEGTASPPA-------TGDSA---
RAQRGSSLPEAS-EVARSAT-SSPTQDPAA--R-PKLQSHPCTPG----------SA-TG
PCVLPLQNCEPIESKLRKKIQGCW

ENSGT00390000013629_0_Linker_12_14 (1525, 1526)

R

PF00036 // ENSGT00390000013629_0_Domain_14 (1526, 1554)

ELLKECKQLDVNRQGEITTSEFLALVEKFNLDISK
EERQQLAMKYDLRNKGTFAYCDFIQGCVLLLKAGETSLLQRLKIQNAHRMXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVLRQYSINLSEEEFFHILEY
YDKTLSSKISYNDFLRAFLQ----------------------------------------
---------------

----------------------------------MCKMAIIPDWLRSHPHM-RKFTHSRP
HSSPCRV-YSRNGSPD-----IFRSSS---TTAVANPTLSSL--DVKRILFQKITD

PF08976 // ENSGT00390000013629_0_Domain_0 (117, 182)

RGDE
LQKAFQLLDTGQNLTVSKSELRRIITDFLMPLTREQFQDVLAQIPLSTSGTVPYLAFLSR
F

ENSGT00390000013629_0_Linker_0_1 (182, 231)

G-GIDLYIN---GIKREG--GNEMNCCHTLRELEIQVGEKVFKNIKTVL

PF13202 // ENSGT00390000013629_0_Domain_1 (231, 253)

KAFKLIDVNK
TGLVQPQELRRVLETFCLKLRDE-EYEK--------------------------------
-------FSKHYNIHNDTAVDYNVFLKNL-SINNDLNLRYCIGNQ---AVSLE-NQQAKN
SKKERLLS-SASSEDTWRNYSLDEIERNFCLELSKSYEKIEKALSAGDPCKGGYVSFNYL
KIVLDTFIYQIPRRIFIQLMKRFGLKATTKINWKKFLTSFHEPR----GLEITSKGPLTK
RNS-IN---SRNESHKENIITKLFRHTEDRFTSLKKALLII-NTKP

PF13833 // ENSGT00390000013629_0_Domain_4 (527, 580)

NGPITREEFRHILN
CVAVK-LSDSEFKELMQTLDPGNTGVVNISVFIDL-VE-KNSRMRK--ASPCT-DTKTPF
LLAWDSVEEIVHDTITRNLHAFYNMLRAYDLGDTGLIGRNNFKKILHVFCPFLTNAHFI-
-KLCSKIQDIGSGRILYKKLLAHMGIDGPPTVSPVHV--PKDQLLSEHLRKDE-QQQPDL
SERTKPTENK--TTQIKKMTTEEVIEKFKNCIQQQDPEFKKRFLDFSKEPNGKINMRDFK
KVLEDTGMPMDDEQYALLTTKIGFEK-EGMSYLDFAAGFED-----PPMRGPETTPP-QP
PTPSKS--YVNSHFITAEECLKLFPR---RLKESFRDPYSAFFKIDTDRDGIINMHDLHK
LLVHLLFNLRDDEFERFLGLLGLRLSVTLNFREFRNLCEKRSLKT-DEAPQRLIRPKQKV
ADSELACEQAHQYLVTKAKNRWSDLSKNFLETDNEGNGILRRRDIKNALYGFDIPLTPRE
FEKLWASYDTEGKGHITY----QEFLQKLGVNYSPAVHRPCA----EDYFNFMGHFTKPQ
QLQEEMKELQQST-------EKAVAARDKLVDCYQDISKAFTKIDKSKTNYISICKMQKV
LEECGCSLTEGELTNLLN----SWGVSRHD-NSINYLDFLRAVEN-SKSTGAQP-KEKE-
---ESMPINFATLNPQEVVRKIQEVVESSQLALSTAFSALDKEDTGFVKSTEFGQVLKDF
CHKLTDNQYHYFLRKLRIHLTPYINWKYFLQSFSCFLEETAEEWA---EKMPKGPPPTS-
PKA

PF08976 // ENSGT00390000013629_0_Domain_11 (1324, 1444)

MASRDILARLHKAVTS----HYHAITQEFENFDTMKTNTISREEFRAVCNRNVQILT
D-------EQFDRLWNEMPVNAKGRLKYPDFLSRFSSERAATPTA-------TGDSA---
AAQRGSSVPDVS-EGIRSAL-SLPNQELRP--G-SKSQSHPCTAA----------STTAI
PGTPPLQNCDPIESRLRKRIQGCWRQLLKECKEKDVARQGDISASEFLALVEKFNLDISK
EECQQLIIKYDLKNNGKFAYCDFIQSCVLLLKAKESSLMQRMKIQNAHKMKDSGAETSSF
YSALLRIQPKIVHCWRPMRRTFKSYDEAG

PF13833 // ENSGT00390000013629_0_Domain_17 (1650, 1698)

TGLLSVADFRTVLRQYSINLSEEEFFHILEY
YDKTLSSNISYNDFLRAFLQ----------------------------------------
---------------

--------MKRNATKTNATKVSRTLSSSNKARDLKYKMAIIPDWLTSYPQT-RKFTYSRP
HSSPCRL-HSKNGFQN-----IFRPSSSS-TTAVANPILSFL--DVKRILFQKITDKG

PF08976 // ENSGT00390000013629_0_Domain_0 (119, 182)

DE
LKKAFQLLDCGQNLTVSKNELRRTITTFLMPLTKEQFQDVLAQIPLTCSGSVPYLEFLSR
F

ENSGT00390000013629_0_Linker_0_1 (182, 231)

G-GIDLNVN---IIKKGG--GNEINCCRTLKELETQMGEKVFKNIKTVT

PF13202 // ENSGT00390000013629_0_Domain_1 (231, 253)

KAFKLIDVNK
TGLVQPHELRRVLETFCLKLRDE-EYSK--------------------------------
-------FSKHYNIDKDTAVDYNVFLKNL-STNNDLNLRYLMGNQ---DVSLE-CQQGKN
SKKEHLLN-SVSPEDTGKTYSLDEIERTFCKEFGKSYEKIEKALGAGDPSKSGYVSFNYL
KIVFDTFVYQLPRRVFIQLMKRFGLKPTTKINWKQFLTSSFEPR----ELDISNMVPPRK
RNG-FS---SRNQSRKKDIITKLFRHSEDCFAALKKALLVI-NTETH

PF13833 // ENSGT00390000013629_0_Domain_4 (528, 580)

GQITGEELRHILN
SMVVK-LSDSEFKELMQTLDPGGTGMIKVSMFVDL-LD-ENPKMRK--ISPCT-DTKTPL
HLAWDSVEEVVHDAIIRSLQAFYNMLQSYDLGDTGLIGRSNFRRLMNIFCPVLTNEYFL-
-KLCSKFQDDASGRIHYRKLLASIGINGPPVVSQVLT--PKDQL-SERFQKVK-EQQPDL
SERTKPTEDK--TTPTKNMTKEEVIKKLKSYIQQQDPAFRKRFLDFGREPNGKINMHEFK
KVLEDTGMPMDDDQYALLTTKIGFKK-EGMSYLDFATGFEGSEWPDTQRTRPKADPP-LT
PISSRS--HLDSHFISAEECLKLFPK---RLKESFRDSYSAFFKTDTDRDGIINMRDLHR
LLLHLLLNLKDEEFERFLGLLGLRLSVTLNFREFRNLCERRPIST-DDVPQRLVRPKQKV
ADSELACEQAHQYLVTKAKNRWSDLSKNFIETDNEGNGILRRRDIKNALYGFDIPLTPRE
FEKLWTSYDTEGKGHITY----QEFLQKLGINYSPTVHRPYA----EDYFNFMGHFTKPQ
QIQDEIKELQQNTEK-------AVPARDKLMDHYQDISKALTKIDKSKNSYLSICKLQKV
LQECGCSLTEEELIDLL----SSWEISWHD-NSVSYADFLEALEN-SMPARAQP-REEE-
---ESPPINFSTLTPEELVKNIQEVVEFSQPDLLKAFSALDKEDTGFIKATEFGQVIKDF
CYKITDSQYNYFLRKLRIHLIPDINWKYFLQNFSSFLEETADEWA---EKMPKAPPPS--
PAAQ

PF08976 // ENSGT00390000013629_0_Domain_11 (1325, 1435)

VDRDLLAQLHKAVTS----HYHAIAQEFENFDTTKTNTASRDEFRAICNRHIQILT
D-------KQFDRLWNEMPVNAKGRLRYLDFLSRFSSERAATPPV-------ASDSL---
EAQRGSSVPEVS-EGARSAVSS-PTQDLRA--G-LRSQSHPCTPA----------RSTE-
-GSPPLQNCEPIESKLRRQIQGCWRELLRECKEKDVNKQGEITSAEFLALVEKFNLDISK
EERQQLLIKYDLKNKGKFAYCNFIQSCVLLLKAKETSLLQRMKIQNANKMKEAGAETSSF
YSALLRIQPQIVHCWRPMRRTFKTYDEAG

PF13833 // ENSGT00390000013629_0_Domain_17 (1650, 1698)

TGLLSVADFRKVLRQYSINLSEEEFFHILEY
YDKTLSSKISYNDFLRAFLQ----------------------------------------
---------------

----------------------------------MYKMETTPYWHMPSSHT-PERTFLRP
HSFPCRV-YSRACFQN-----MLRPSST--ATAIANPVLSSH--DVKRILFQKVAESRD

PF00036 // ENSGT00390000013629_0_Domain_0 (120, 148)

E
LKKAFQLLDTAQNLTVTQSELQKAINTFLLPLTKEQFRDLLAQIPLTSSGAVPYLEFLSK
FG-GKDLNGS---IINRGY--GTEMGHSRTLKELEIQLGDKVFRNIK

PF00036 // ENSGT00390000013629_0_Domain_1 (228, 256)

TVIKAFKLLDVNG
SGLVYPHQLRRVLETFCVKMSAK-EYDM--------------------------------
-------FSRHYSIGQN-KVDYNVFLKNF-SINHEMNLRHFAGNQ---DNSWK-NQHSKP
SSQERLST-SGLPEDVWENCSIEEIEKVFCQELLKSFEKVEKGLSAGDPCGSGFVSLNYL
KIVLDTFVYRLPRRVFLQLMTRFGLKTTAKINWKQFLTSFYNPP----WLSLGNSVPMTR
RNS-FN---SRNQPDKENIITKLSRRAEEHCTSLKKALLLS-MKKCDGSITGKELQRTLR
SSAIE-VSDSELRELMQVLDPRRTGLVRACSVLNLLLEEENRKIRK--RSPRT-GSTTSF
HLAWDSVEEMVRDGITRNLQAFYNMLQSYDLGDTGFIGHSNFKKIMRIFCPLLTGEHV--
SELCSKFQDAASGRILYKKLLANIGINGLPTASPDPV--PTGQLVIEPVRKAQQQQQSAL
AERIKPTEEE--TPVTKNLTRDEVIEKLRLCIQQGDPSFQKQFLDFSKEPNGKINKEDFQ
KVLEAMGMPMDAAEYSLLTTKLGFNK-EGMSYLDFATGFEE-------MSGSGSAGA-QT
PVLSAS--YVNSHFITAEECLKLFPR---RVKEFFRDPYS

PF00036 // ENSGT00390000013629_0_Domain_6 (881, 905)

AFFKIDSNRDGIISMQDLHK
LLLHLLLNLKDEEFERFLELLGLKLSITLNFREFRSLCEKGSYGL-DEAPQRLIRPKQKV
TDAELACEQAHQYLVTKAKHRWPDLSKNFIETDNKGNGILRRRDIKNALYGFDIPLTPR

PF00036 // ENSGT00390000013629_0_Domain_8 (1020, 1047)

E
FEKLWTRYDTEGRGFITY----QEFLQKLGISYSPVVHRPYA----EDHFNFLGHFTKPQ
QVQEEIRELQQTTEE---------ATRDKLKGHFQEISKALSELDQTKEGCIPLSKMQAA
LQECGCTLKAAELAQLLN----SWGVSWQD-NSVNYLDFLKAVDS-SKPARPPS-TEKE-
---ESKPIDFAALGPEEVLKKMQEVVNSSQE

PF00036 // ENSGT00390000013629_0_Domain_10 (1232, 1260)

ALSKTFSELDQEDTGFVKAAEFGQVLKDF
CHKLSDSQYHYFLRKLRIHLSPHINWKYFLQNFNSFLEETAAEWA---EKMPKDPPP---
PKDMGKRDILDRLHKAVTS----HYNAIVQEFENFDTMKTNAVSRDEFRAICNRH

PF08976 // ENSGT00390000013629_0_Domain_12 (1376, 1525)

VQILT
D-------DQFDRLWSEMPVTSKGKLNYQEFLSKFSSKAVTAPASS--------DS----
PNAQGSSARDIS-KCTISTQ------LSPR--R-PKMRSHPCXXX----------XXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLVEKFNLDISK
EESQQLIIKYDLKNNGKFAYCDFIQSCILLLKAKETSLMQRMKIQNMHKMXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVLRQYSINLSEEEFFHILEY
YDK-LSSKISYNDFLRALQ-----------------------------------------
---------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------

PF08976 // ENSGT00390000013629_0_Domain_11 (1398, 1444)

MPVNAKGRLKCPDFLSRFSSETPATPMA-------SGDSA---
AAQRGSSVPDIS-ESTRSAL-SSPTRELRP--G-SKSRSHPCTPA----------NTATI
LGTPPLQNCDPIESRLRKRIQGCWRELLKECKEKDVGRQGNINASEFLALVEKFNLDISK
EECQQLIIKYDLKNNGKFAYCDFIQSCVLLLKAKETSLMQRMKIQNAHKMKEAGAETSSF
YSALLRIQPKIVHCWRPM

PF13499 // ENSGT00390000013629_0_Domain_17 (1639, 1698)

RRTFKSYDEAGTGLLSVADFRMVLRQYGINLSEEEFFHILEY
YDKTLSSKISYNDFLRAFLQ----------------------------------------
---------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------FIETDNEGNGILRRRDIKNALYGFDIPLTPRE
FEKLWQSYDTEGRGHITY----QEFLQKLGIAYSPGVHRPYT----EDYFNFMGHFTKPQ
QVQEEIKVLQQHRDT----AEKPSAARDKLLAHCDDISKALAKEGKSRSGSVPVSRMQEL
LGECGCPLREEELAALLSR--ASWGVSLHD-NSINLADFLRALES-GRPGPEPPDKEED-
---GGVVVDFSTVTLPEVVRSVQQVVGSCQPALSQAFSALDKEDAGFVKAAEFGDVLRAF
CHGLVDSQYHHLLRKLRLHLAPYVHWKYFLENFGSFREEEEAPASSEVAKMSSLPPCAL-
PRPRRGQSPLVTSHEGLVSGWWWGYWNCTREFHFFGVQRVNLLRSESTRQCCLQRVF

PF08976 // ENSGT00390000013629_0_Domain_12 (1378, 1524)

LFS
D-------VEFDRLWSEMPVNAKGRLKYLDFLSRFSSEQAATPAA-------SGDSA---
GAQRGSSVPELS-ESTRSAV-ALPSCELSA--G-LKPRSHSRNRA----------AGCRV
PAHPGLTSCLPIHTSFRSEATAAWSQVG----VGAVVRQGGVGRSESLGLVEKFSLDVSP
EESRRLLAKYDLRNTGRFAYCAFLQSCVLLLQAKETSLLHRLKIQNAHKMEEAGAETASF
YAALLRIQPKIVHCWRPMRRTFKTYDASGSGLLSVADFRKVLRLYSINLSEEEFFHILEY
YDKTLSSRISYNDFLRAFLQ----------------------------------------
---------------

----------------------------------TCKMAIIPDWLRSHPHM-RKFTHSRP
HSSPCRV-YSRNGSPN-----MFRSSS---TTAVANPTLSSL--DVKRILFQKITD

PF08976 // ENSGT00390000013629_0_Domain_0 (117, 182)

RGDE
LQKAFQLLDTGQNLTVSKSELRRIITDFLMPLTREQFQDVLAQIPLSTSGTVPYLAFLSR
F

ENSGT00390000013629_0_Linker_0_1 (182, 231)

G-GIDLYIN---GIKREG--GNEMNCRRTLRELEIQVGEKVFKNIKTVL

PF13202 // ENSGT00390000013629_0_Domain_1 (231, 253)

KAFKLIDVNK
TGLVQPQELRRVLETFCLKLRDE-EYEK--------------------------------
-------FSKHYNIHSDTAVDYNVFLKNL-SINNDLNLRYCIGNQ---EVSLE-NQQAKN
SKKERLLS-SASSEDTWRNYSLDEIERNFCLELSKSYEKIEKALSAGDLCKSGYVSFNYL
KIVLDTFIYQIPRRIFIQLMKRFGLKATTKINWKKFLTSFHEPR----GLEITNKGPLTK
RNS-IN---SRNESHKENIITKLFRHTEDRFTSLKKALLII-NTKP

PF13833 // ENSGT00390000013629_0_Domain_4 (527, 580)

SGPITREEFRHILN
CVAVK-LSNSEFKELMQTLDPGNTGVVNISVFIDL-VE-KNSRMRK--TSPCT-DTKTPF
LLAWDSVEEIVHDTITRNLHAFYNMLRAYDLGDTGLIGRNNFKKILHVFCPFLTNAHFI-
-KLCSKIQDIGSGRILYKKLLAHIGIDGPPTVSPVLV--PKDQLLSEHLRKDE-QQQPDL
SERTKPTENK--TTRIKRMTIEEVIEKFKNCIQQQDPEFKKRFLDFSKEPNGKINVHDFK
KVLEDTGMPMDDEQYALLTTKIGFEK-EGMSYLDFAAGFED-----PPMRGPETTPP-QP
PTPSKS--YVNSHFITAEECLKLFPR---RLKESFRDPYSAFF

PF13202 // ENSGT00390000013629_0_Domain_6 (884, 901)

KIDTDRDGIINMHDLHR
LLLHLLFNLKDDEFERFLGLLGLRLSVTLNFREFRNLCEKRSLKT-DEAPQRLVRPKQKV
ADSELACEQAHQYLVTKAKNRWSDLSKNFLETDNKGNGILRRRDIKNALYGFDIPLTPRE
FEKLWASYDTEGKGHITY----QEFLQKLGVNYSPAVHRPCA----EDYFNFMGHFTKPQ
QLQEEMKELQQST-------EKAVAARDKLADRYQDISKAFTKIDKSKTNYISICKMQKV
LEECGCSLTEGELTNLLN----SWGVSRHD-NSINYLDFLRAVEN-SKSTGAQP-KEKE-
---ESMPINFATLNPQEVVRKIQEVVESSQLALSTAFSALDKEDTGFVKATEFGQVLKDF
CYKLTDNQYHYFLRKLRIHLTPYINWKYFLQNFSCFIEETADEWA---EKMPQGPPPTS-
PKA

PF08976 // ENSGT00390000013629_0_Domain_11 (1324, 1444)

VAGRDILARLRKAVTS----RYHAITQEFENFDTTKMNTISREEFRAVCNRNVQILT
D-------EQFDRLWNEMPVNAKGRLKYPDFLSRFSSERAATPTA-------TGDSA---
AAQRGSSVPDVS-EGIRSAL-SLPNQELRP--G-SKSQSHPCTPV----------STTAI
PGTPPLQNCDPIESRLRKRIQGCWRQLLKECKEKDAARQGDISVSEFLALVEKFNLDINK
EECQQLIIKYDLKNNGRFAYCDFIQSCVLLLKAKESSLMQRMKIQNAHKMKDAGAETSSF
YSALLRIQPKIVHCWRPMRRAFKSYDEAG

PF13833 // ENSGT00390000013629_0_Domain_17 (1650, 1698)

TGLLSVADFRTVLRQYSINLSEEEFFHILEY
YDKTLSSKISYNDFLRAFLQ----------------------------------------
---------------

--------------------------MRKGLGDLTCKMAVVPDWHIMCPYT-RKFTHSRP
HSSPCRV-YSRSAFQN-----MFRPSSS---TTVANPILSSL--DVKRILFQKITERGDE
LKRAFQLLDTARSMTVTKSELRRVITAFLLPLTREQFQDVLAQIPLTSSGAVPYLVFLSR
FG-GIDLSIN---VIKRGG--ENEMNGCRTLKELEAQVGEKIFKNIKTIIKALMLIDVNT
TGLVQPHELRRVLETFCLKMKDE-EYKK--------------------------------
-------FAQHYDIDKDAAVDYKVFLKNL-SSNNDLNLKYNTGSQ---EVLWE-NQRVKS
SKREEPPS-SAVSDNIWKNYSLDEIETAFCLELSKCYEKVEKALSAGDPCTSGYVSLNYL
KIVLDTFVYRLPRRVFIQLMKRFGLKTTTKVNWKQFLTSFYEPQ----YE-GSNKAPLTK
RNS-IN---FRNQVHKENIITKLFRHE-DHYTSLKKALLLI-KSKPDGQITGQELQRVLN
CVVVN-ISDSEFKELMRILDPGCTGCVNISKFIEL-IE-ENPKLHK--IPACK-DTKMPL
FLAWDSVEEIIHDSIAKNPSAFCNMLRSYDIGDTGLIGRNNFKKIMRVFCPFLTTEHLV-
-KLCSKFQDIASGRILYKKLLACLGINRPPTVSPVSV--PKGQLLNEQLQKEE-QPLPDL
SERAKPAESQ--GAMARNMTKEEVIEKLKSCIRQQDPALRKRFLDFTREPDGKINTHDFK
KVLEDNGMPMDDDQYALLTTKLGYKK-EGMSYLDFAAGFED-----PKMNGAEVTPP-QT
PALPKG--DVDSFFVTAEECLRQFPR---RLKEFFRDPYAAFFKMDTDRDGILTMYDLHR
LLQHLLFNLKDEEFERLLGLLGLRLSVTLNFREFRNLCEKRSFCTDDDAPQRLLRPKQKV
ADSELACEQAHQYLVTKAKTRWSDLSKNFIETDSEGNGILRRRDVKNALYGFDIPLTPRE
FEKLWMRYDSEGRGHITY----QEFLQKLGINYSADVHRPFV----EEYLNFMGHFTKPQ
QVQEELKELQQSTEK-------AAAARDKLKDHDQDISKALAKLDKSQTGYISLGRLRKL
LQECGCCLKEEELIDLLNR--TSWGIGWHN-NSINYLDFLRAVEN-SKPTKPQS-QEKE-
---ESMPINFAALNPEEVLKNIQEVVAASSLALSMAFSALDKEDTGFVKASDFGQVLKDF
CYKLTDNQYHYFLRKLRLHLTPYINWKYFLQNFSSYVEETAVEWA---EKMPRGPRPLS-
PKEMANQELLARLHKAVTS----HYHAIAQEFENFDTMKTNTTSRDEFRSICTRH

PF08976 // ENSGT00390000013629_0_Domain_12 (1376, 1525)

VQVLT
D-------EQFDRLWEEMPVNSKGRLKYLDFLSSFNVDKPATPSA---------------
EPQRGSSAPEVL-DRGRSAGSS-PTRDPKA--G-SKSRSHPCTPS----------SV---
SGTPPLQNCEPIETKLRKKVQGCWRELLRECKERDPNRQGEIPGPDFLALVEKFHLDITR
DECQQLLVKYDLKNNGKFAYCSFMQSCVLLLKAKETSLMQRMKIQNANKMKEAGAETCSF
YSALLRIQPKIVHCWRPMRRTFKAYDEGGTGFLSVADFRKVLRQYSINLSEEEFFHILEY
YDKTLSSKISYNDFLRAFLQ----------------------------------------
---------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------MMTLGDAFC
F-------

PF08976 // ENSGT00390000013629_0_Domain_11 (1389, 1442)

SQFDRLWSEMPVNAKGRLKYQEFLSRFSMERAAAPPA-------TGNST---
QAQKGSSVPKVS-ERTQSAV-SSPTHDLQA--G-SKSWSQPCTPT---------------
-GTPALQNCEPIESRLRKQVQGCWRELLKECKEKDRARLGTITAPEFLALMEKFHLDVSK
EETQQLLVKYDLRDNGTFAYCDFIQSCVLLLRAKETSLMQRVKIQNAHKMKEAGTETSSF
YKALLQIQPKTLHCWRP

PF13499 // ENSGT00390000013629_0_Domain_17 (1638, 1698)

MRRMFKAYDKGGTGFLSAEDFRKVLRQFSINLSEEEFFHLLEY
YDKTLSSKVFYNDFLRAFLQ----------------------------------------
---------------

----------------------------------MCKMAIIPDWLRSHPHT-RKFTHSRP
HSSPCRV-YSRNGSPN-----KFRSSS---TTAVANPTLSSL--DVKRILFQKITD

PF08976 // ENSGT00390000013629_0_Domain_0 (117, 199)

RGDE
LQKAFQLLDTGQNLTVSKSELRRIITDFLMPLTREQFQDVLAQIPLSTSGTVPYLAFLSR
FG-GIDLYIN---GIKRGD--GNEMNCCRTLRELEIQVGEKVFKNIKTVMKAFELIDVNK
TGLVRPQELRRVLETFCLKLRDE-EYEK--------------------------------
-------FSKHYNIHKDTAVDYNVFLKNL-SINNDLNLRYCMGNQ---EVSLE-NQQAKN
SKKERLLG-SASSEDIWRNYSLDEIERNFCLQLSKSYEKVEKALSAGDPCKGGYVSFNYL
KIVLDTFVYQIPRRIFIQLMKRFGLKATTKINWKQFLTSFHEPQ----GLQVSSKGPLTK
RNS-IN---SRNESRKENIITKLFRHTEDRSASLKKALLII-NTK

PF13833 // ENSGT00390000013629_0_Domain_4 (526, 578)

PDGPITREEFRYILN
CVAVK-LSDSEFKELMQMLDPGDTGVVNTSMFIDL-IE-ENCRMRK--TSPCT-DAKTPF
LLAWDSVEEIVHDTITRNLQAFYNMLRSYDLGDTGRIGRNNFKKIMHVFCPFLTNAHFI-
-KLCSKIQDIGSGRILYKKLLARIGIDGPPTVSPVLV--PKDQLLHEHLQKDE-QQQPDL
SERTKLTEDK--TTLTEKMTAEEVIEKFKKCIQQQDPAFKKRFLDFSKEPNGKINVHDFK
KVLEDTGMPMDDDQYALLTTKIGFEK-EGMSYLDFAAGFED-----PPMRGPETTPP-QP
PTPSKS--YVNSHFITAEECLKLFPR---RLKESFRDPYSAFFKTDADRDGIINMHDLHR
LLLHLLLNLKDDEFERFLGLLGLRLSVTLNFREFQNLCEKRPWRT-DEAPQRLIRPKQKV
ADSELACEQAHQYLVTKAKNRWSDLSKNFLETDNEGNGILRRRDIKNALYGFDIPLTPRE
FEKLWARYDTEGKGHITY----QEFLQKLGINYSPAVHRPCA----EDYFNFMGHFTKPQ
QLQEEMKELQQST-------EKAVAARDKLMDRHQDISKAFTKTDQSKTNYISICKMQEV
LEECGCSLTEGELTRLLN----SWGVSRHD-NAINYLDFLRAVEN-SKSTGAQP-KEKE-
---ENMPISFATLNPQEVVRKIQEVVESSQLALSTAFSALDKEDTGFVKATEFGQVLKDF
CYKLTDNQYHYFLRKLRIHLTPCINWKYFLQNFSCFLEETADEWA---EKMPKGPPPTS-
PK

PF08976 // ENSGT00390000013629_0_Domain_11 (1323, 1444)

ATADRDILARLHKAVTS----HYHAITQEFENFDTMKTNTISREEFRAICNRHVQILT
D-------EQFDRLWNEMPVNAKGRLKYPDFLSRFSSETAATPMA-------TGDSA---
VAQRGSSVPDIS-EGTRSAL-SLPTQELRP--G-SKSQSHPCTPA----------STTVI
PGTPPLQNCDPIESRLRKRIQGCWRQLLKECKEKDVARQGDINASDFLALVEKFNLNISK
EECQQLIIKYDLKNNGKFAYCDFIQSCVLLLKAKESSLMHRMKIQNAHKMKEAGAETPSF
YSALLRIQPKIVHCWRPMRRTFKSYDEAG

PF13833 // ENSGT00390000013629_0_Domain_17 (1650, 1698)

TGLLSVADFRTVLRQYSINLSEEEFFHILEY
YDKTLSSKISYNDFLRAFLQ----------------------------------------
---------------

----------------------------------MCKMAITPDWLRSHSRA-RKFTHSRP
HSSPCRV-YSRNGSPN-----MFRSCS---PTAVANPTLSSL--DVKRILFQKIT

PF08976 // ENSGT00390000013629_0_Domain_0 (116, 203)

DRGEE
LKKAFQLLDTGQNSTVSKSELRRIIADFLMPLTREQFQDVLAQIPLSTSGTVPYLDFLSR
FG-GIDLYVT---GIKRGD--E

ENSGT00390000013629_0_Linker_0_1 (203, 230)

NEMNGCCTLKELEIQVGEKVFKNIKTV

PF13202 // ENSGT00390000013629_0_Domain_1 (230, 253)

MKAFKLIDVNK
TGLVQPQELRRVLETFCLKLRDE-EYEK--------------------------------
-------FSKHYNVHKDTAVDYNVFLKNL-SINNDLNCRYFVGNQ---EVSVA-NQQAKK
SKKERLLS-SASSEGVWRNHSLDEIERNFCLELSKSYEKIEKALSAGDPCKGGYVSFNYL
KIVLDTFVYQLPRRIFIQLMKRFGLKATTKINWKQFLTSFHEHQ----GLEISNKVSLTK
RNS-IN---SRNESHEENIITKLFRHTEDRSPSLKKALLII-NTK

PF13833 // ENSGT00390000013629_0_Domain_4 (526, 575)

PDGQIPREEFRHILN
RVAVK-LSNLEFKELMQTLDPGDTGVVNTSMLIDL-IE-ENSRMRK--NSPCT-DTKTPL
LPAWDSVEEVVHDTITKNLQAFYNMLCSYDLGNTGLIGRNNFKKIMHVFCPFLTNAHFI-
-KLCSKFQDIASGRIFYKKLLAYIGIDGPPTVPPVLV--PKDQLLSERLQKDE-QQQPDL
SKRTKATGDQ--TTPTKKMTKEEVTEKLRNHIQQQDPAFKRRFLDFGKEPNGKISMHDFK
KVLEDIGMPMDDDQYALLATKIGFEK-EGMSYLDFAAGFED-----PPMRGPEATPPLQP
PTPSKS--YMNSHFITAEECLKLFPR---KLKESFRDPYSAFF

PF13202 // ENSGT00390000013629_0_Domain_6 (884, 901)

KIDTDRDGIINMHDLHR
LLLHLLLNLKDQEFERFLGFLGLRLSVTLNFREFRNLCEKRPLST-DEAPQRLIRPKQKV
ADSELACEQAHQYLVTKAKNRWSDLSKNFIETDNEGNGILRRRDIKNTLYGFDIPLTPRE
FEKLWARYDTEGRGHITY----QEFLQKLGINYSPAVHRPCM----QDYFNFMGHFTKPQ
QLQEEMKELQQST-------EKAVPARDKLMDHYQDISKALTKIDKSKTNYISICKMQKV
LEECGCSLTEEELTHLLN----SCGVSRRD-NSINYLDLLRALED-SKSTGIQP-KEKE-
---ESMPINFATLNPQEVVRRIQEVVESSHPALSTAFSALDKEDTGFVKPTEFGQVLKDF
CYNLTDNQYHYFLRKLRIHLAPYINWKYFLQNLSCFLEETADEWA---EKMPKSSPPSS-
PKA

PF08976 // ENSGT00390000013629_0_Domain_11 (1324, 1442)

VANRDLLTRLHKAVTS----HYHAIAQDCENFDTMKTNTISRDEFRAICTRHIQILT
D-------EQFDRLWNEMPVNAKGRLKCPDFLSRFSSETPATPMA-------LGDSG---
TAQRGSSVPDIS-ESTRSAL-SSPTRELRP--G-SKSRSHRCTPA----------NTATI
PGTPPLQNCDPIESRLRKRIQGCWRELLKECKAKDVGRQGDINTSEFLALVEKFNLDISK
EECQQLIIKYDLKNNGKFAYCDFIQSCILLLKAKETSLMQRMKIQNAHKMKEAGAETSSF
YSALLRIQPKIVHCWRPMRRTFKSYDEAG

PF13833 // ENSGT00390000013629_0_Domain_17 (1650, 1698)

TGLLSVADFRTVLRQYGINLSEEEFFHILEY
YDKTLSSKISYNDFLRAFLQ----------------------------------------
---------------

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--------------------------------------MTGSKV--KEKGMP-GSAGRTP
PQGQSKQDLPTKLRETLRA----HSTPLAQALADADPPQAGTVTKEDFRGICSLRFPLW

PF08976 // ENSGT00390000013629_0_Domain_12 (1380, 1525)

S
D-------EQFENLWSHMPLDTSGKLKYRDFLAKFCRKTATPPLTSTDP---------AG
VPERGSKPASLSGGSTRSPQ-SKTA---------PAPTSHSQTPERPVCPERLVPLSAAQ
TQVPPLLACKSSEWKLRNKIQSCWKALLKECSGKDLDQQGEMATADFWAVAEKFGLDLSK
DEQQQLTAKYDKKSNGRFAYCDFLQGYVLLFTAKKPSLLRRLKIQKFPTLVCQP------
------------------------------------------------------------
------------------------------------------------------------
---------------

----------------------------------MRKMAIKPDWLTSGPQM-RKCPYSRP
HSSPCRL-YSKNVFQD-----MFRPSSS--TPAVANPILSFL--DVKRILFQKITDRGDE
LKKAFQLLDPGQNLTVSKNELRRTITGFLMPLTREQFQDVLAQIPLTRSGAVPYLEFLSR
FG-GIDLNIN---VLKKGS--ENEMNCCRTLKELEIQIGEKVFKNIKTIIKAFNLIDVNK
TGLIQPHELRRVLETFCLKFRDE-EYCK--------------------------------
-------FSKHYNIDKEPTVDYNAFLKNL-SINNDLNLRYYMINQ---DVSCE-HQQGKS
PKKEHLLN-YMSSKDVWKYYTLDELGSAFYQEFSKSFEKIEKALSAGDPAKSGYVSFNYL
KVVLDTFICQLPRRVFIQLMKRFGLKATTKINWKQFLTSFQEPQ----DMDINIMVPPRK
RNS-IN---SRNQSCKKDTVTKLFTRSDDRFASLKTALLII-NAKTNGQISEQELRQVLD
NKVIK-LNDADFKELMQTLDPGGTGMAKVSTFIDL-LE-ENPKMRK--ISPCT-D-RTPL
LLAWGSVEEAVREAINRSPQAFYSMLRTSDTADTGILGRSNFKRIMLIFCPFLTNKHFV-
-RLCSKFQDIASGGILYKKLLESLGINVLPTVSSAPA--PKDPF-CAHFHKAE-QEHLDL
SERTKPTKEK--TTPAKNMTKEEVIEKLKNCIQQQDPAFRRRFLDFGKEPNGKISVREFR
KVLEDTGMPMDDDQYALLTRKIGYKE-EGMSYLDFATGFED-----IPRSGPEASPP-QT
PVYSKS--RQNSHFITAEECLKLFPK---RLKEEFRDSYSAFFKMDTDMDGIISMRDLHR
LLLQMLLNLKDEEFERFLALLGLRLSVTLNFREFRNLCEKRPFRG-DERPQRIIRPKQKV
TDSDLACEQAHQYLATKAKNRWLDLSKHFLETDSEGNGILRRWDIKNALYGFDIPLTPKE
FEKLWLSYDTEGKGHITY----QEFVQKLGINYSPTSHRPYA----EDYFNFMGHFTKPQ
QIQEEIKELQQSSEK-------AAPARDKLMDHYQDISKALAKIDKSKNGYISIHKLQKV
LQECGCPLKEEELTNLLTR--TSWGIGWPN-NSVSYPDFWRALEN-SKPR-PPA-KEKE-
---ENLLVDFSTLPPEEVVRTIQDVVDSAHPALLKAFSALDKEDTGFVKAAEFGQVIKDF
CYKLTDNQYHYFLRKLRIHLVPYINWKYFLQNFSYYLEETADEWA---EKMPKGPLLSS-
PVDMATKDLLARLHKAVTS----HYYAITQEFDKFDTTKTNTISKEEFRAICTRH

PF08976 // ENSGT00390000013629_0_Domain_12 (1376, 1525)

VQILT
D-------DQFNRLWNEMPVNTKGRLRCLDFLCRFSSERPATPPA-------AGDSS---
EAQRGSSVPELS-ERARSAMSAAAPQDLRV--G-LKSRSHPCTPA----------SSMAS
PSALPLQNCEPIESKLRRRIQGCWRQLLKECKEKDPNKHGEITAAEFLAFVEKFSLDISK
EECHQLMVKYDLRNNGKFAYPDFIQSCVLMLKTKETSLLQRLKIQNANKMKEAGAETSSF
YSALLRIQPKIMHCWRPMRRTFKTYDEAGTGLLNVADFRRVLRQYSINLSEEEFFHILEH
YDKTLSSKISYNDFLRAFLQ----------------------------------------
---------------

--------MRRNSPQTNAATVNSTKSCGTKARDLMCKMAVIRDWHISYPPT-HKFMNLRP
HSSPCRV-YSRNGSQR-----VFRPSS---TTAMANPILSFL--DVKRILFQKITDKGD

PF13499 // ENSGT00390000013629_0_Domain_0 (120, 179)

E
LRKAFQLLDTNHNMTVSKSELKRIITTFLMPLTREQFQDVLAQIPLTSSGAVPYLEFL

ENSGT00390000013629_0_Linker_0_1 (179, 231)

SR
FG-GMDLHVN---VIKRGG--GNEMNCSRTVKELEIQVGEKIFKNMKTVI

PF13202 // ENSGT00390000013629_0_Domain_1 (231, 253)

KAFKLIDVNK
TGLVQPHELRKVLETFCLKMKDD-EYKK--------------------------------
-------FAKHYNIDKDTTVDYNVFLKNL-SVNNDLNLRYKTGNP---EVSWE-SQSVKN
SKRECPHS-SVSSEEVWKNCSLEEVETAFCQEASCGSC-----LHLLGP-----------
------------------------------------------------------------
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---------------

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-----------------------------------------MSSTTPSATSPVPSTNPAT
------CTSSQP---EHPKTPSSLVGQKST-----SASSRPQ---------------TTT
ACSVPVPKWEEIENKIRKNIQCSWRDILKLCQEKDISKLGEIPVSEFLEIVEKFHLDLSK
EEINQITTKYDIKKNGKFAYYDFFQSCVLLLKPQKSTLLQRVIIPKPQKPMSPGPQSTLF
YSTMLRIQPQILHCWRPM

PF13499 // ENSGT00390000013629_0_Domain_17 (1639, 1698)

KRTFKSYDESRTGLLNVADFRQVLHEYKINLSEEELFNILEY
YDKTLSSKISYNDFLRAFLQ----------------------------------------
---------------

--------MKRSSTKTHEATVNSTKSCSTKARDLMHKMANVTDWHISYPYT-RKFMNLRP
HSSPCRV-YSRNGFQN-----MLRPFSS--ATAIANPILSFL--DVKRILFQKITDKGDE
LKKAFELLDTSHNMTVSKNELRRIITTFLMPLTREQFQDVLAQVPLTSSGAIPYLEFLSR
FG-DMDLNIN---VIKKGG--ENEVSRSRTVKELETQIGEKIFKNIKTVIKALKLIDVNK
TGLIQPCELRKVLETFCLKMKSD-EYRK--------------------------------
-------FAQHYNIGKDTAVDYNVFLRNL-SMNNDLNLRYSGGSQ---EISWN-NQPVKN
SKEECLHS-SASSENVWKNRSLDEIERTFCQELPKAYEKVEKALSAGDPSKSGYVSLNYL
KIVLDTFVYRLPRRIFIQLMKRFGLKTTSKINWKQFLTSLYESQ----WMEVNSTVPLTK
RNS-IT---SGNQSCKEDIVTKLSRHE-DHCTSLKKALLMA-NTKPDGRIIGEELRRLLN
CMVVK-ISDSEFKELMQTLDPGHTGWVNIHTLIEL-LE-ESSKIRK--LSACT-DTTAPL
LPAWDSVEKIVQDSITRNLHAFCRMLQSYDLRDTGLIGRNNFKKIMRIFCPFLTIEHLL-
-KFCNKFQDTASGRILYKKFLECMGISGPPAVSPVLG--PKDQLLSEHFQKEE-EQELEV
SERTKPAEDR--SALTKSRTKDEVIENLKNHKQQQDPAFGKLFLDLSKEPNGKINVRDFK
KVLDASGMPVDDDQLARLTAKIGYKK-DGMSYLDFAAGFED-----AKMNGPESTPL-QP
PVLSKN--NLDSDFITAEECLKQFPQ---RLKEAFRDPYSAFFKIDSDRDGIINMHDLRR
LLLHLLFNLKDEDFERFLGLLGLRLSVTLNYREFRNLCEKRPFRM-DDAPQRLIRPKQKV
ADSELACEQAHQYLVTKAKTRWSDLSKNFIETDNEGNGILRRRDVKNALYGFDIPLTPRE
FEKLWMRYDTEGRGHITY----QEFLQKLGINYSADMHQPYA----EDYFNFMGHFTKPE
QIQEEVKQLEQSVDR-------AMLVREKLKDHYQDISKALTRLDKSRNGYMSMGRMHKV
LQECGCSLTEEELTDLLN----SWGISWHD-NSFNYLDFLKAVES-SKPTRPQP-KEKE-
---ENTPVNFSTLDPEEIVKNIQEVVASSDVALSTAFSALDKEDTGFVKAADFGQVLKDF
CYKLTDNQYHYFLRKLKIHLTPLINWKYFLQNFSSFFEETAAEWA---EKMPKGPPSMF-
PKETANQELLARLHKAVGS----HYHAIAQEFENFDTMKTNSASRDEFRAICSRH

PF08976 // ENSGT00390000013629_0_Domain_12 (1376, 1525)

VQILT
D-------EQFDRLWSEMPVNAKGRLKYPDFLSMFSSERMATPPT-------ASSSV---
KAQRGSSVPEVS-YRSRSAV-SSPTHDLKA--G-LKPPSHPCTPT----------SVGSA
PGPLPLQNCEPIESKLRKQVQGCWREFLKECKEKDVSKQGEVTAAEFLALVEKFSLDISK
EESQQLIVKYDLKNNGRFAYCDFIQSCVLLLKAKETPLMQRMKIQNAHKMKESGAETSSF
YSALLRIQPKIVHCWRPMRRTFKAHDEGGTGLLNVADFRKVLRQYSINLSEEEFFHILEY
YDKTLSSKISYNDFLRAFLQ----------------------------------------
---------------

-------------------------------RDLMCKMAITPDLHTLHPHA-RKFNYLRP
HSSPCRV-YSRNGFQN-----IFRPSSS--TTAVANPVLSFL--DVKRILFQKITDKGDE
LKKAFQLLDTGQNQTVSKAELRRAITTFLLPLTREQFQDLLAQIPLTSSGAVPYLEFLSR
FG-GIDLNVN---VIKRRT--RNEMNQNRPLKELEVQAGEKIFKNIKSVFKALKLIDVNK
TGLVQPHELRRVLETFCLKMSND-EYKK--------------------------------
-------FSNHYNIDKDTAVDYNAFLKNL-STNNELNLKYVMGNQ--VEVSGE-NQQAEY
SKKESLPR-SVSSEDVWKNYNLDEIERTFCQELSKSYENVEKALSAGDPTKGGYVSLNYL
KIVLDTFVCRLPRRIFILLMKRYGLKTTSKISWKQFLTLFYEPQ----WSGTSNTALMTK
RNRYSS---CRNQSCKKNIVTKLRRHAEDHLPLLKKALLVR-STKPGGYITGKELQHLLN
CTILK-ISDSEFKELMQTLDPGDTGLVNLNLFFEL-FEEENLKIRK--CSPCT-DNKTPL
PLAWDSVEEMVHDAINRNLHAFYSMLQSNDLGDTGLISRNSFKKAMCMFCPFLTNEHLI-
-KLCSKFQDIASGRILYKELLASIGINHPPTVSPILV--PKDQPLSEHIQKGE-QQCLDL
AKRAKPTEDR--TT----VTKEEVIEKLKNYIQQQDPAFRKRFLDFSKEPKGKINEHEFR
KVLEDTGMPMDDEQYALLTRKIGFEK-EGMSYLDFATGFED-----TKMSWPEAATS-QP
LVFTKN--DLDSHFISAEECLQLFPQ---RLKELFRNPYSAFFKVDTDRDGIINMHDLHR
LLLHLLFNLKDKEFERFLSLLGLRLGVTLNFREFQNLCEKRQFRS-DEAPQRIIRPKQKV
TDSELACKQAHQYLATKAKNRWSDLSKNFIETDNEGNGILRRRDIKNALYGFDIPLTPRE
FEKLWMRYDTEGRGHITY----QEFLQKLGINYSPAVHRPYA----EDYFNFMGHFTKPQ
QVREEIKELQQNIEK-------VMPVRDQLKDFYQDISNALTKLDKSKNGYIPISKLQKA
LQECGCSLTEEELTHLLNRHGPSWGISWHD-NHVNYPDFLKAVND-SKPLKPQP-SDKE-
---ESQPINFATINSEEVVKKIQEVVASSHPALLKVFSALDKEDTGFIKATEFGQVLKDF
CYKLTDNQYHYFLRKLRIHLTPYINWKYFLQNFSCFLEETAVEWA---EKMPKGPPPMS-
PKERAERDILGCLRKAVTS----HYSAIAQEFENFDTMKTNTASRDEFRAICTRH

PF08976 // ENSGT00390000013629_0_Domain_12 (1376, 1525)

VQILT
D-------EQFDRLWSEMPVDARGRLKYQDFLTKFSAGKAETPPA-------SSDSG---
RAQRGSSVPQLS-A-----------WDSQE--G-PRARSHPCTPP----------GTAPR
PSTPPLQNCEPIENKLRKKIQGCWRELLKECKGKDANKQGEVTTSEFLALVEKFHLDISK
EECQQLIVKYDLKNNGKFAYCDFIQSCVLLLKAKDTSLMQRLRIQNIHKMKEAGAETSSF
YSALLRIQPKIMHCWRPMRRTFKTYDEGGTGFLNVADFRKVLRQYSVNLSEEEFFHILEY
YDKTLSSKISYNDFLRAFLQ----------------------------------------
---------------

MGSPSETPRLGG-PRTR-VPAQLGGESRRGPRDLMCKMAIIPDWLRSHPHT-RKFTHSRP
HSSPCRV-YSRNGSPN-----KFRSSS---TTAVANPTLSSL--DVKRILFQKIADRGDE
LQKAFQLLDTGQNLTVSKSELRRIITDFLTPLTREQFQDVLAQIPLSTSGTVPYLAFLSR
FG-GIDLYIN---GIKRGG--GNEMNCCRTLRELEIQVGEKVFKNIKTVMKAFKLIDVNK
TGLVRPQELRRVLETFCLKLRDE-EYEK--------------------------------
-------FSKHYNIHNDTAVDYNVFLKNL-SINNDLNLRYCMGNQ---EVSLE-NQQARN
SKKERLLG-SASSEDIWRNYSLDDIERNFCLELSKSYEKIEKALSAGDPCKGGYVSFNYL
KIVLDTFIYQIPRRIFIQLMKRFGLKATTKINWKQFLTSFHEPQ----GLQVSNKGPLTK
RNS-IT---SRNESRKENIITKLFRCTEDRSASLKKALLII-NTKPDGPITREEFRYILN
CVAIK-LSDSEFKELMQILDPGDTGVVNTSMFIDL-IE-ENCRMRK--TSPCT-DAKTPF
LLAWDSVEEIVHDTIARNLQAFYNMLRSYDLGDTGLIGRNNFKKIMHVFYPFLTNAHFI-
-KLCSKIQDIGSGRILYKKLLACIGIDGPPTVSPVLV--PKDQLLSEHLQKDE-QQQPDL
SERTKPTEDK--TTLTKKMTTEEVIEKFRKYIQQQDPAFKKRFLDFSKEPNGKINVHDFR
KILEDTGMPMDDDQYALLTTKIGFEK-EGMSYLDFAAGFED-----PPMRGLETTPP-QP
PTPSKS--YVNSHLITAEECLKLFPR---RLKESFRDPYSAFFKTDVDRDGIINMHDLHR
LLLHLLLNLKDDEFERFLGLLGLRLSVTLNFREFQNLCEKRPWRT-DEAPQRLIRPKQKV
ADSELACEQAHQYLVTKAKNRWSDLSKNFLETDNEGNGILRRRDIKNALYGFDIPLTPRE
FEKLWARYDTEGKGHITY----QEFLQKLGINYSPAVHQPCA----EDYFNFMGHFTKPQ
QLQEEMKELQQST-------EKAMAARDKLMDLHQDISKAFTKIDKSKTNYISICKMQKV
LEECGCSLTEGELTHLLN----SWGVSRHE-NAINYLDFLRAVEN-SKSTGAQP-KEKE-
---ESMPISFATLNPQEVVRKIQEVVESSQLALSTAFSALDKEDTGFVKATEFGQVLKDF
CYKLMDNQYHYFLRKLRIHLTPYINWKYFLQNFSCFLEETADEWA---EKMPKGPPPTS-
PKAMADRDILARLHKAVTS----HYHAITQEFENFDTMKTNTISREEFRAICNRH

PF08976 // ENSGT00390000013629_0_Domain_12 (1376, 1525)

VQILT
D-------EQFDRLWNEMPVNAKGRLKYPDFLNRFSSETAATPMA-------TGDSA---
VAQRGSSVPDVS-EGTRSAL-SLPTQELRP--G-SKSQSHPCTPA----------STTEI
PGTPPLQNCDPIESRLRKRIQGCWRQLLKECKEKDVARQGDINASDFLALVEKFNLDISK
EECQQLIIKYDLKNNGKFAYCDFIQSCVLLLKAKESSLMHRMKIQNAHKMKEAGAETSSF
YSALLRIQPKIVHCWRPMRRTFKSYDEAGTGLLSIADFRTVLRQYSINLSEEEFFHILEY
YDKTLSSKISYNDFLRAFLQ----------------------------------------
---------------

----------------------------------MCKMAIIPDWLRSHPHT-RKFTHSRP
HSSPCRV-YSRNGSPN-----KFRSSS---TTAVANPTLSSL--DVKRILFQKITD

PF08976 // ENSGT00390000013629_0_Domain_0 (117, 199)

RGDE
LQKAFQLLDTGQNLTVSKSELRRIITDFLMPLTREQFQDVLAQIPLSTSGTVPYLAFLSR
FG-GIDLYIN---GIKRGD--GNEMNCCRTLRELEIQVGEKVFKNIKTVMKAFELIDVNK
TGLVRPQELRRVLETFCLKLRDE-EYEK--------------------------------
-------FSKHYNIHKDTAVDYNVFLKNL-SINNDLNLRYCMGNQ---EVSLE-NQQAKN
SKKERLLG-SASSEDIWRNYSLDEIERNFCLQLSKSYEKVEKALSAGDPCKGGYVSFNYL
KIVLDTFVYQIPRRIFIQLMKRFGLKATTKINWKQFLTSFHEPQ----GLQVSSKGPLTK
RNS-IN---SRNESRKENIITKLFRHTEDRSASLKKALLII-NTK

PF13833 // ENSGT00390000013629_0_Domain_4 (526, 578)

PDGPITREEFRYILN
CVAVK-LSDSEFKELMQMLDPGDTGVVNTSMFIDL-IE-ENCRMRK--TSPCT-DAKTPF
LLAWDSVEEIVHDTITRNLQAFYNMLRSYDLGDTGRIGRNNFKKIMHVFCPFLTNAHFI-
-KLCSKIQDIGSGRILYKKLLARIGIDGPPTVSPVLV--PKDQLLHEHLQKDE-QQQPDL
SERTKLTEDK--TTLTEKMTTEEVIEKFKKCIQQQDPAFKKRFLDFSKEPNGKINLHDFK
KVLEDTGMPMDDDQYALLTTKIGFEK-EGMSYLDFSAGFED-----PPMRGPETTPP-QP
PTPSKS--YVNSHFITAEECLKLFPR---RLKESFRDPYSAFFKTDADRDGIINMHDLHR
LLLHLLLNLKDDEFERFLGLLGLRLSVTLNFREFQNLCEKRPWRT-DEAPQRLIRPKQKV
ADSELACEQAHQYLVTKAKNRWSDLSKNFLETDNEGNGILRRRDIKNALYGFDIPLTPRE
FEKLWARYDTEGKGHITY----QEFLQKLGINYSPAVHRPCA----EDYFNLMGHFTKPQ
QLQEEMKELQQST-------EKAVAARDKLMDRHQDISKAFTKTDQSKTNYISICKMQEV
LEECGCSLTEGELTRLLN----SWGVSRHD-NAINYLDFLRAVEN-SKSTGAQP-KEKE-
---ESMPISFATLNPQEVVRKIQEVVESSQLALSTAFSALDKEDTGFVKATEFGQVLKDF
CYKLTDNQYHYFLRKLRIHLTPCINWKYFLQNFSCFLEETADEWA---EKMPKGPPPTS-
PK

PF08976 // ENSGT00390000013629_0_Domain_11 (1323, 1444)

ATADRDILARLHKAVTS----HYHAITQEFENFDTMKTNTISREEFRAICNRHVQILT
D-------EQFDRLWNEMPVNAKGRLKYPDFLSRFSSETAATPMA-------TGDSA---
VAQRGSSVPDIS-EGTRSAL-SLPTQELRP--G-SKSQSHPCTPA----------STTVI
PGTPPLQNCDPIESRLRKRIQGCWRQLLKECKEKDVARQGDINASDFLALVEKFNLNISK
EECQQLIIKYDLKNNGKFAYCDFIQSCVLLLKAKESSLMHRMKIQNAHKMKEAGAETPSF
YSALLRIQPKIVHCWRPMRRTFKSYDEAG

PF13833 // ENSGT00390000013629_0_Domain_17 (1650, 1698)

TGLLSVADFRTVLRQYSINLSEEEFFHILEY
YDKTLSSKISYNDFLRAFLQ----------------------------------------
---------------

-------------A-----VRLNFSKSVFFVATLMNKMMTVPDWHTLYVPT-RKAQCSRP
HSSPSSV-CPKNSVQS-----MLRPSSS--PSAAENPVLSFL--DIKRILFQKINDRKDE
LRKAFQLLDPGRSLTVTKGELKRVIGTFLLPLTREQFQDLLAQIPLTGSGNVPYLEFLSK
FG-GSDLNIN---VIKRGG--GHEMDSCRTLKELEIQIGEKVFRNPKAVIKAFRLLDVSS
TGRVQPQQLRRVLETFCLQMTEE-EYQK--------------------------------
-------FSKHYGIDKDTAVDYGVFLKNL-SKSNDVHLRYFMGNQ---EVSPE-NPQART
LKREHWLS-STPSEESWGGYSLDDIEKAFCREFSKSIDKIEKALSAGDPSRGGYVSLNYL
KVVLDTFVCRLPRRLFLQLMKRFGFKTTARINWKQFLTSYYELQ----GLEASNTVPPLK
RDS-TH---SRSRSRRENAVTKLLRRAEASSEPLRKALLMSSSTK

PF13833 // ENSGT00390000013629_0_Domain_4 (526, 578)

PGGRMTGDELRQILS
ATLVK-VSDSEFRELMRTLDPEATGVVTAGSFLDL-LE-ASPKTRK--TSPCT-GAKTPL
PLAWVSVEAMVHDAIAKNLQAFCNMLQSYDLRDTGLMAQSNFKAVMRVFCPFLTHEHLK-
-KLCCKFQDPTSEKILYKKLLACIRVSGSPTVS------PKDQP-CGHFQKEE-G---QF
SGRTKPTRDR--TPTIKNMTRDEAIENLKSRIKRQDPVFRKRFLEVSGGLLGKIGLRDFK
KVLEDSGMPMDEVQYSLLATKIGFRK-EGMSYLDFAVGFEG-----TGGHTPPRTCP-A-
-GASRL--SLIGHFVTAEECLKLFPK---RLRESFRDPYSAFF

PF13202 // ENSGT00390000013629_0_Domain_6 (884, 901)

KIDTDRDGIISMRDLHR
LLQQLLFNLKDEEFERLLGLLGLRLSVTLNFREFQSLCEKGPSPM-DEAPQRLLRPKQKV
ADSELACEQAHQYLVIKAKTRWTDLSKNFIETDTEGNGILRRRDIKNALYGFDIPLTPRE
FEKLWQSYDTEGRGYITY----QEFLQKLGINYSPTVHRPYA----EDYFNFLGHFTKPQ
QVQEEIQELQQSTER----AKPARWA--------------------------WESRRSQV
LQECGCPLQEEELAALLN----SLGIICHD-NTINYLDFLRALES-SRAARPQR-EEKE-
---DAVPINFSTLNPEEVVKSVQEVVSTSQQALSQAFSALDKDDTGFVKATDFGQVLKDF
CHKLTDSQYHLFLRKLRIHLTPSIHWKYFLETFGCFLEEAADEWA---ERMPRVPPPTS-
PREA

PF08976 // ENSGT00390000013629_0_Domain_11 (1325, 1441)

AIAELLARLQKAVTT----HHHAFAQEFKNFDTNKSNTVSRDEFRAVCTRHLQILT
D-------EQFDRLWGEMPVTARGRLKYQEFLSRFGVEQVASPPA-------TGDSV---
QAQKGSSVPQVS-NRTQSAI-SSPTRDLRA--E-LKSRSHPCTPA---------------
-GDLPLQNCEPVESRLRKQVQGCWRALLKDCKEKDPARLGTIAAPDFLALVQQFRLDLSK
EESQQLLTKYDLKNNGTFAYCDFIQNCVLLLRATETSLMRRLKIQNTHKMKEAGAESCSF
YAALLRIQPKILHCWRPMRRMFKAYDQGG

PF13833 // ENSGT00390000013629_0_Domain_17 (1650, 1698)

TGILSADDFRKVLRQFSINLSEEEFFHLLEY
YDKTLSSKVSYNDFLRAFLQ----------------------------------------
---------------

----------------------------------MCKMAIIPDWLRSHPHM-RKFTHSRP
HSSPCRV-YSRNGSPD-----IFRSSS---TTAVANPTLSSL--DVKRILFQKITD

PF08976 // ENSGT00390000013629_0_Domain_0 (117, 182)

RGDE
LQKAFQLLDTGQNLTVSKSELRRIITDFLMPLTREQFQDVLAQIPLSTSGTVPYLAFLSR
F

ENSGT00390000013629_0_Linker_0_1 (182, 231)

G-GIDLYIN---GIKREG--GNEMNCCHTLRELEIQVGEKVFKNIKTVL

PF13202 // ENSGT00390000013629_0_Domain_1 (231, 253)

KAFKLIDVNK
TGLVQPQELRRVLETFCLKLRDE-EYEK--------------------------------
-------FSKHYNIHNDTAVDYNVFLKNL-SINNDLNLRYCIGNQ---EVSLE-NQQAKN
SKKERLLS-SASSEDTWRNYSLDEIERNFCLELSKSYEKIEKALSAGDPCKGGYVSFNYL
KIVLDTFIYQIPRRIFIQLMKRFGLKATTKINWKKFLTSFHEPR----GLEITSKGPLTK
RNS-IN---SRNESHKENIITKLFRHTEDRFTSLKKALLII-NTKP

PF13833 // ENSGT00390000013629_0_Domain_4 (527, 580)

NGPITREEFRHILN
CVAVK-LSDSEFKELMQTLDPGNTGVVNISVFIDL-VE-KSSRMRK--ASPCT-DTKTPF
LLAWDSVEEIVHDTITRNLHAFYNMLRAYDLGDTGLIGRNNFKKILHVFCPFLTNAHFI-
-KLCSEIQDIGSGRILYKKLLAHMGIDGPPTVSPVHV--PKDQLLSEHLRKDE-QQQPDL
SERTKPTENK--TTQIKKMTTEEVIEKFKNCIQQQDPEFKKRFLDFSKEPNGKINVRDFK
KVLEDTGMPMDDEQYALLTTKIGFEK-EGMSYLDFAAGFED-----PPMRGPETTPP-QP
PTPSKS--YVNSHFITAEECLKLFPR---RLKESFRDPYSAFFKIDTDRDGIINMHDLHK
LLVHLLFNLRDDEFERFLGLLGLRLSVTLNFREFRNLCEKRSLKT-DEAPQRLIRPKQKV
ADSELACEQAHQYLVTKAKNRWSDLSKNFLETDNEGNGILRRRDIKNALYGFDIPLTPRE
FEKLWASYDTEGKGHITY----QEFLQKLGVNYSPAVHRPCA----EDYFNFMGHFTKPQ
QLQEEMKELQQST-------EKAVAARDKLVDCYQDISKAFTKIDKSKTNYISICKMQKV
LEECGCSLTEGELTNLLN----SWGVSRHD-NSINYLDFLRAVEN-SKSTGAQP-KEKE-
---ESMPINFATLNPQEVVRKIQEVVESSQLALSTAFSALDKEDTGFVKSTEFGQVLKDF
CHKLTDNQYHYFLRKLRIHLTPYINWKYFLQSFSCFLEETAEEWA---EKMPKGPPPTS-
PKA

PF08976 // ENSGT00390000013629_0_Domain_11 (1324, 1444)

MASRDILARLHKAVTS----HYHAITQEFENFDTMKTNTISREEFRAVCNRNVQILT
D-------EQFDRLWNEMPVNAKGRLKYLDFLSRFSSERAATPTA-------TGDSA---
AAQRGSSVPDVS-EGIRSAL-SLPNQELRP--G-SKSQSHPCTAA----------STTAI
PGTPPLQNCDPIESRLRKRIQGCWRQLLKECKEKDVARQGDISASEFLALVEKFNLDISK
EECQQLIIKYDLKNNGKFAYCDFIQSCVLLLKAKESSLMQRMKIQNAHKMKDSGAETSSF
YSALLRIQPKIVHCWRPMRRTFKSYDEAG

PF13833 // ENSGT00390000013629_0_Domain_17 (1650, 1698)

TGLLSVADFRTVLRQYSINLSEEEFFHILEY
YDKTLSSNISYNDFLRAFLQ----------------------------------------
---------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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LQEFNYYLDDEQFNSLLN----RLGISIHD-SKLSYFDFLRAIDD-GRASKYQ-QRQKP-
---AAPPASFAMLSLEKTLIKIKEIVTSSYDLLYKAFSLFDKEGTGAVTALEFHQVLDHF
CFKLTDKQFRHLLKKLKLYENHTVDWKFFLKNCDLLLETEEG---------QKVAQPKS-
SQELSKKEILTRIQEVVTA----RFNTITQEFKDTDCEKVNTVSKEDFRGICNRYFL

PF08976 // ENSGT00390000013629_0_Domain_12 (1378, 1525)

LLT
D-------GQFEDLWNSVSVDADGRLKYCDFLKKFNCEAVTMPSDTQAMNSAACPSKPAT
PAEPGSRLPSQP---SRPKTAASP-----SVQVKTPVSSRPH---------------TAV
AWSPPLLNCEPIENKIRKIIQHSWREILKACKEKDVDRLGEVSKSDFLAIAEKFNLNLSK
EEFSQITTKYDIKNNDRFAYCDFLQSCVLLMKPQESSLLQRMSIQKPRISRSPGPQTLTF
FNAMLRIQPQILHCWRPMRRTFKSYDESGSGLLSVQDFRQVNCLY---------------
------------------------------------------------------------
---------------

--------MK-----------QGSTKGNTKARNLMNKMMNIPGGHALYPHT-RKFTCSRP
HSSPCRV-YSKNDFQN-----IFRPSSS--PSAAANPILSFL--DVKRILFQ

PF08976 // ENSGT00390000013629_0_Domain_0 (113, 182)

KITDKKDE
LKKAFQLLDASQNLTVTRSELRRIITTFLLPLTKEQFQDVLAQIPLTSSGNVPYLEFLSR
FG-GVDLNIN---VIKRGG--GNEVNCCRTLKELEIQIGEKIFRNAKTIIKAFQLVDVNN
IGLVQPQELMRVLETFCLKMKEE-EYRK--------------------------------
-------FSKHYNIDKDTAVDYNMLLKNL-SINNDLHFRYFMSNQ---EVSPE-NQQAKT
FKREHLLN-SAPSKESWNNCSLDDVEKVFCQEFSKSVDKIEKALSAGDPSRGGYVSLNYL
KIVLDTFVYRLPRKTFLQLMKR--------------------------------------
------------------------------------------------------------
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---------------

----------------------------------MCKMAVVPDWHIICPYT-RKFTHSRP
HSSPCRV-YSRSVFQN-----MFRPSSS---TTVANPILSSL--DVKRILFQKITEKGDE
LKRAFHLLDTANNMTVTKSELRRVITTFLLPLTREQFQDVLAQIPLTSSGAVPYLVFLSR
FG-GIDLNIN---VIKRGG--ENEMNGCRTLKDLEAQVGEKIFKNIKTVIKALMLIDVNT
TGLVQPHELRRVLETFCLKMKDE-EYKK--------------------------------
-------FAQHYNIDKDAAVDYNVFLKNL-GSNNDLNLKYNMGSQ---EVLWE-NQRVKS
FKREEPPS-SAVSDNIWKNYSLDEIETAFCLELSKCYEKVEKALSAGDPCTSGYVSLNYL
KIVLDTFVYRLPRRIFIQLMKRFGLKTTTKVNWKQFLTSFYEPQ----YE-ASSKAPLTK
RNS-IN---FRNQVHKENVITKLFRHE-DHDSSLKKALLLI-KSKPDGQITGQELQRILN
CMVVK-ISDSEFRELMRILDPGCTGCVNVSRFIEL-IE-ESPKLHK--IPAYK-DTKMPL
FLAWDSVEEIIHDSIAKNLSAFCNMLRSYDLGDTGLIGRNNFKKIMRVFCPFLTTEHLV-
-KLCSKFQDIASGRILYKKLLACLGINRPPTVSPVSM--PKGQLLNEHLQKEE-QPLPDH
SERATPAESQ--GAVTRNMTKDEVIEKLKSCIQQQDPAFRKRFLDFTKEPNGKIHTHDFK
KVLEDYGMPMDDDQYALLTTKLGYKK-EGMSYLDFAAGFED-----PKMNEPEVTPP-QT
PVLPKG--DVDSFFVTAEECLRQFPR---RLKEFFRDPYAAFFKMDTDRDGILTMHDLHR
LLQHLLFNLKDEEFERLLGLLGLRLSITLNFREFRNLCEKRSFSADDDAPQRLPRPKQKV
ADSELACEQAHQYLVTKAKTRWSDLSKNFIETDSEGNGILRRRDMKNALYGFDIPLTPRE
FEKLWMRYDSEGRGHITY----QEFLQKLGINYSADIHRPYA----EEYFNFMGHFTKPQ
QVQEELKELQQSTEK-------AMPARDKLKDHDQDISKALAKLDKSRTGYISLGRLQRL
LQECGCSLKEEELIDLLNR--TSWGIAWHN-NSINYLDFLRAVEN-NKLTRPQS-QEKE-
---ESVPINFAALSPEEVLKNIQGVIAASSLALSTAFSALDKEDTGFVKASDFGQVLKDF
CYKLTDNQYHYFLRKLRLHLTPYINWKYFLQNFSSYVEETAVEWA---EKMPRGPRPLS-
PKEMANQELLARLHKAVTS----HYHAIAQEFENFDTMKTNTASRDEFRSICTRH

PF08976 // ENSGT00390000013629_0_Domain_12 (1376, 1525)

VQVLT
D-------EQFDRLWEEMPVNSKGRLRYLDFLSSFNVDKQATPLA-------TSDSA---
KAQRGSSVPEVS-DRGRSAGSS-PTRDPKA--G-SKPRSHPCTPS----------SV---
SGTPPLQNCEPIETKLRKKVQGCWRELLRECKERDFNKQGEIPGPEFLALVEKFNLDISR
DECQQLLIKYDLKNNGKFAYCSFIQSCVLLLKAKETSLMQRMKIQNANKMKEAGAETCSF
YSALLRIQPKIVHCWRPMRRTFKAYDEGGTGLLSVADFRKVLRQYSINLSEEEFFHILEY
YDKTLSSKISYNDFLRAFLQ----------------------------------------
---------------

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---------------------------------------------------MMTLGDAFC
F-------

PF08976 // ENSGT00390000013629_0_Domain_11 (1389, 1442)

SQFDRLWSEMPVNAKGRLKYQEFLSRFSMERAAAPPA-------TGNST---
QAQKGSSVPKVS-ERTQSAV-SSPTHDLQA--G-SKSWSQPCTPT---------------
-GTPALQNCEPIESRLRKQVQGCWRELLKECKEKDRARLGTITAPEFLALMEKFHLDVSK
EETQQLLVKYDLRDNGTFAYCDFIQSCVLLLRAKETSLMQRVKIQNAHKMKEAGTETSSF
YKALLQIQPKTLHCWRP

PF13499 // ENSGT00390000013629_0_Domain_17 (1638, 1698)

MRRMFKAYDKGGTGFLSAEDFRKVLRQFSINLSEEEFFHLLEY
YDKTLSSKVFYNDFLRAFLQ----------------------------------------
---------------

------------------------FAIANPSSDLMNKMAVLPDWQALYPQT-RKSNYSRP
HSSPCKV-PLKNSFQN-----MFRPSSSTSTTAIANPILSSL--DIKRILFQKI

PF08976 // ENSGT00390000013629_0_Domain_0 (115, 184)

SDKRDE
LKKVFQLLDTGQNQTVSKNELRRTITTFLLPLTREQFQDVLAQLPLTSSGSVPYMEFLSK
FG-

ENSGT00390000013629_0_Linker_0_1 (184, 230)

GIDLNIN---VIKRGN--GSEMDSCRTLKELESQIGEKVIRNKKTI

PF13202 // ENSGT00390000013629_0_Domain_1 (230, 252)

IKAFQLIDINN
TGRVRPQELRRILETFCLKMKEE-EYQM--------------------------------
-------FSKHYSLDQETAVDYSVFLKNL-NISNDLNARYLLGNQ--GK--------GLK
SIHELILD-SELSEEMWKNCSLSDIQNILSQELLKSYQKVEKALSAGDPCRGGYVSLNYL
KVVLDTFVYPLPRKIFIQLMRRLGFRTTAKINWKQFLTSFYEQQ----GLETSNAPPPQR
RNG---------RFRKENIIRKLFKYSEDRSISLKKALLKS-NTT

PF13833 // ENSGT00390000013629_0_Domain_4 (526, 579)

PDGQIKWEDLRYILD
CMVVK-LSDAEFNELRQVFDPDDLGVVNISSFMDL-LED-T---RK--ISLNT-DSKIPF
LLAWDSVEEKVQDAIFRNQPAFYDMLQSYDLGNTGTIGRNNFKKVMRIFCPFLTNEQFI-
-RFCNKFHDLTSGRIFYKKLMASLGVNGHPAVSPSSK--DKPGG---QTQKQE-------
-------PKN--SPENKTMTKEEVIKKLKNCIQQQDPVFRKHFLDISKDPDRKIAKQDFR
KVLEDSGMPMEDTQFAELTSKIGYRK-EGMSYLDFAAGFED-----SKMSQPVTSPA-LS
PLPSKP--YSSSHLITAEECLRLFPK---RMKEFFPDPYSAFF

PF13202 // ENSGT00390000013629_0_Domain_6 (884, 902)

KIDTDMDGIISMHDFYR
LLLQLLLNMKDDEFERFLGLLGLRLSVTLNFREFRNLCEKRPLRT-DDAPQRLIRTKQKA
ADSDLACEQAHQYLVAKAKNRWVDLSKNFIETDTEGNGILRRRDIKNALYGFDIPLMPRE
FERLWHSYDTEGRGYITY----QEFLQKLGISFLPAVHRPNK----EDYFNFMGHFTKPQ
QLQEEIQELIFS-------------SRAKLMDHYKEISKALSTQDKAKVGSVSLFRLYKL
LQDCGCPLKEEELTRLIS----SLEIEVHE-NSINYLDFLRALES-SGAT----------
---GPQSIDFSTLSPEEIVKSIQCLVSCSQQALFQVFSAVDKEDTGFVKATDFGQVLKEF
CCKLTDNQYHYFLRKLKIHLTPFIHWKYFLQNFSSFTEEAADEWA---EKMPKDVPLQS-
PHEM

PF08976 // ENSGT00390000013629_0_Domain_11 (1325, 1424)

GSRDLLARLHKAVTA----HYHTFIQEFENFDTLKSNTISRDEFRSICARHMQILT
D-------GQFDRLWAEMPVNSRGKLKYQDLLSRLSSLRPASPAS-------PASPA---
SPARGSSTPEIS-EDTRCV--SSPNRDTKT--G-SKGRSHLCTPT----------S----
-GNPSLQNCESIETKLRKQIHGCWRELLRECKERDVDKQGSITASDFLALVEKFHLNISK
EESQKLLVKYDLKNNGQFAYCDFIQSCVLLLKAKETSLMRRLKIQNANKM----------
------------------------------------------------------------
------------------------------------------------------------
---------------

----------------------------------ICKMAIIPDWLRSHSRA-RKFTHSRP
LSSPCRI-YSRNGSSN-----MFRSCS---PTAVANPTLSSL--DVKRILFQKIT

PF08976 // ENSGT00390000013629_0_Domain_0 (116, 199)

DRGDE
LKKAFQLLDTGQNSTVSKSELRRIITDFLMPLT-EQFQDVLAQIPLSTSGTVPYLDFLSR
FG-GTDLYIN---GIKRG

ENSGT00390000013629_0_Linker_0_1 (199, 230)

D--ENEMNGCRTLKELEIQVGEKVFKNIKTV

PF13202 // ENSGT00390000013629_0_Domain_1 (230, 253)

MKAFKLIDVNK
TGLVQPQELRRVLETFCLKLRDE-EYEK--------------------------------
-------FSKHYNVHKDTAVDYNVFLKNL-SINNDLNLRYFVGNQ---EVSLE-DQQANN
SKKERFLS-SASSEDIWRNYSLDEIERNFCLELSKSYEKIEKALSAGDPCKGGYVSFNYL
KIVLDTFVYQLPRRIFIQLMKRFGLKATTKINWKQFLTSFHEHQ----GLEISNKGSLTK
RNS-IN---SRNESHKENIITKLFRHTEDRSASLKKALLII-NTKP

PF13833 // ENSGT00390000013629_0_Domain_4 (527, 580)

NGPITREEFRHILN
CVAVK-LSNLEFKELMQTLDPGDTGVVNTSMLIDL-VE-ENSRMRK--KSPYT-DTKTPL
LLAWDSVEEVVHDTITKNLQAFYNMLCSYDLGDTGLIGRNNFKKIMHVFCPFLTNAHFI-
-KLCSKFQDIASRRIFYKKLLAHIGIDGPPTVSPVLV--PKDQLLSERLQKDE-QQQPDL
SKRTKATGDQ--TTLTKKMTKEEVIEKLKNCIQQQDPAFKRRFLDFSKEPNGKINMHDFK
KVLEDTGMPMDDHQYALLATKIGFEK-EGMSYLDFAAGFED-----PPMRGPEATPPLQP
PTPSKS--YVNSHFITAEECLKLFPR---RLKESFRDPYSAFF

PF13202 // ENSGT00390000013629_0_Domain_6 (884, 901)

KIDTDRDGIINMHDLHR
LLLHLLLNLKDQEFERFLGFLGLRLSVTLNFREFRNLCEKRPLRT-DEAPQRLIRPKQKV
ADSELACEQAHQYLVTKAKNRWSDLSKNFIETDNEGSGILRHWDIKNALYGFDIPLTPRE
FEKLWARYDTEGRGHITY----QEFLQKLGINYSPAVHRPCM----EDYFNFMDHFTKPQ
Q--EEMKELQQGT-------EKAVPARDKLMDHYQDISKALTKIDKSKTNYISIGKMQKV
LEECNCSLTEEELTHLLN----SWGVCWRD-NSINYLNLLRALEN-SKSTGAQP-KEKE-
---ESMPINFATLNPQEVVRRIQEVVEFSQPALSTAFSALDKEDTGFVKATEFGQVLKDF
CYNLTDNQYHYFLRKLRIHLAPYINWKYFLQNLSSFIEETAEEWA---EKMPKSSPSSS-
SKA

PF08976 // ENSGT00390000013629_0_Domain_11 (1324, 1444)

VANRDLLAHLHKAVTS----HYHAIAQDCENFDTMKTNTISRDEFRAICTRHIRILT
D-------EEFDRLWNEMPVNAKGRLKCPDFLSRFSSETPATPMA-------LGDSA---
AAQRGSSVPDIS-ESTRSAL-SSPTREPRP--G-SKSRSHPCTPA----------NTAAI
PGTPPLQNCDPIESRLRKRIQGCWRELLKECKEKDVGRQGDINASEFLALVEKFNLDISK
GECQQLIIKYDLKNNGKFAYYDFIQSCVLLLKAKETSLMQRMKIQNAHKMKEAGAETSSF
YSALLRIQSKIVHCWRPMRRTFKSYDEAG

PF13833 // ENSGT00390000013629_0_Domain_17 (1650, 1698)

TGLLNVADFRTVLRQYGINLSEEEFFHILEY
YDKTLSSKISYNDFLRAFLQ----------------------------------------
---------------

----------------------------------MCKMAIIPDWLRSHPHM-RKFTHSRP
HSSPCRV-YSRNGSPN-----MFRSSS---TTAVANPTLSSL--DVKRILFQKITD

PF08976 // ENSGT00390000013629_0_Domain_0 (117, 182)

RGDE
LQKAFQLLDTGQNLTVSKSELRRIITDFLMPLTREQFQDVLAQIPLSTSGTVPYLAFLSR
F

ENSGT00390000013629_0_Linker_0_1 (182, 231)

G-GIDLYIN---GIKREG--GNEMDCCRTLRELEIQVGEKVF-NIKSVL

PF13202 // ENSGT00390000013629_0_Domain_1 (231, 253)

KAFQLIDVNK
TGLVQPQELRRVLETFCLKLRDE-EYEK--------------------------------
-------FSKHYNIHSDTAVDYNVFLKNL-SINNDLNLRYCIGNQ---VVSLE-NQQAKN
SKKERLLS-SASSEDTWRNYSLDEIERNFCLELSKSYEKIEKALSAGDPCKSGYVSFNYL
KIVLDTFIYQIPRRIFIQLMKRFGLKATTKINWKKFLTSFHEPR----GLEITNKGPLTK
RNS-IN---SRNESHKENIITKLFRHTEDRFTSLKKALLII-NTKP

PF13833 // ENSGT00390000013629_0_Domain_4 (527, 580)

NGPITREEFRHILN
CVAVK-LSDSEFKELMQTLDPGNTGVVNISVFIDL-VE-KNSRMRK--TSPCT-DTKTPF
LLAWDSVEEIVHDTITRNLHAFYNMLRTYDLGDTGLIGRNNFKKILHVFCPFLTNAHFI-
-KLCSKIQDIGSGRILYKKLLAHIGIDGPPTVSPVLV--PKDQLLSEHLRKDE-QQQPDL
SERTKPTENK--TTQIKKMTTEKVIEKFKNCIQQQDPEFKKRFLDFSKEPNGKINVHDFK
KVLEDTGMPMDDEQYALLTTKIGFEK-EGMSYLDFAAGFED-----PPMRGRETTPL-QP
PTPSKS--YVNSHFITAEECLKLFPR---RLKESFRDPYSAFF

PF13202 // ENSGT00390000013629_0_Domain_6 (884, 901)

KIDTDRDGIINMHDLHR
LLLHLLFNLKDDEFERFLGLLGLRLSVTLNFREFRNLCEKRSLKT-DEAPQRLIRPKQKV
ADSELACEQAHQYLVTKAKNRWSDLSKNFLETDNEGNGILRRRDIKNALYGFDIPLTPRE
FEKLWASYDTKGKGHITY----QEFLQKLGVNYSPAVHRPCA----EDYFNFMGHFTKPQ
QLQEEMKELQQST-------EKAVAARDKLADRYQDISKAFTKIDKSKTNYISICKMQKV
LEECGCSLTEGELTNLLN----SWGVSRHD-NSINYLDFLRAVEN-SKSTGAQP-KEKE-
---ESMPINFATLNPQEVVRKIQEVVESSHLALSTAFSALDKEDTGFVKATEFGQVLKDF
CYKLTDNQYHYFLRKLRIHLTPYINWKYFLQNFSCFLEETADEWA---EKMPQGPPPTS-
PKA

PF08976 // ENSGT00390000013629_0_Domain_11 (1324, 1444)

VASRDILARLQKAVTS----HYHAITQEFENFDTMKTNTISREEFRAVCNRNVQILT
D-------EQFDRLWNEMPVNANGRLKYPDFLSRFSSERAATPTA-------TGDSA---
AAQRGGSVPDVS-EGIRSAL-SLPNQELRP--G-SKSQSHPCTPA----------STTAI
PGTPPLQNCDPIESRLRKRIQGCWRQLLKECKEKDVARQGDISASEFLALVEKFNLDINK
EECQQLIIKYDLKNNGKFAYCDFIQSCVLLLKAKESSLMQRMKIQNAHKMKDAGAETSSF
YSALLRIQPKIVHYWRPMRRTFKSYDEAG

PF13833 // ENSGT00390000013629_0_Domain_17 (1650, 1698)

TGLLSVADFRTVLRQYSINLSEEEFFHILEY
YDKTLSSKISYNDFLRAFLQ----------------------------------------
---------------

--------MKRNGNHIKAIKANSTKSCSTKARDLTHKMAIIPNWQSFCPHP-RKYTSSRP
HSSPGRV-YSKNGFQN-----MFRPSSS--TTTVANPILSFL--DVKRILFQK

PF08976 // ENSGT00390000013629_0_Domain_0 (114, 234)

ITDKRDE
LKKAFQLLDTGQNLTVSKSELRRTIAAFLLPLTREQFQEVLAQVPVTGSGNVPYLEFLSR
FA--------------------------------------------------FKLIDVNK
TGLVQPQELKRLLETFCLKMTDE-EYER--------------------------------
------------------------------------------------E-----------
----HLPS-FVASDSIWDNCSLDDIERTFCREFSKSHEKVEKALSAGDPSKGGYVSLNYL
KVVLDTFVYWLPRRIFLQLMKRFGLKTTSKINWKHFLASFNEPQ----EFEVSYMVSSKK
PSS-LG---SRNQPQKESIVTKLFRHGEDSYMALKKALLIINTVRFETLLIE-KL-----
-IVSK-KAN------------TQSKTNKNSVFTH-------LSIQR-TTLPCA-ESKMPL
HLAWNSVEE

PF08976 // ENSGT00390000013629_0_Domain_5 (610, 694)

MVQDAITRHLQAFYDTLQSYDLRDTGTISRSNFKKIMHTFCPFLTNEHLT-
-KLSSKFQDTVSGRILYKKFLACVGIKDLPTMPPICV--SKDKS-SEHFQKEQ-QPLPDL
SERTEMVGPS--GDRSNNLV----------------------NQKIGQGDQGLSTLTSLR
QVLEDSGMPMDDTQFSQLTTKIGFKK-EGMSYLDFAAGFEGTEAK----------PG---
----HPACWGFHGDAEPPECLKLFPR---RLKEHFQVSRTT--------CGSTCPAPWH-
----------REPLRRFMSPLNLNTVIYYF--------------------FFLSRTKQKV
ADSELACEQAHQYLVIKAKNRWADLSKNFLETDNEGNGILRRRDIKNALYGFDIPLTPRE
FEKLWQSYDTEGRGHITY----QEFLQKLGLRYSPTVHRPYA----EDYFNFLGHFTKPQ
QVQEEIQELQQSTER----------AVAKLEDHYQDISKALTTLDKSKSGSVSLCKLRKV
LRDCGCPLKEVELSSLLN----SWGISQQD-NSVNYLDFLRALEKRA-LEKSQLGSPQSR
DQEGSLPINFSTLSPEEIVRNMQEAVESAQPALLQAFSALDKEDTGFVNATEFGQVLKDV
CCQLSDNQYHYFLRKLRIHLVPYINWKYFLETFSSFLEETADEWA---EKMPRIPTSSS-
PGD

PF08976 // ENSGT00390000013629_0_Domain_11 (1324, 1443)

MANRDILERLHRAVAS----HPHTIAQELENFDTTKTNTVSRDEFRAVCARHVQILT
D-------EQFDRLWSEMPVNAKGRLKYPDFLSRFGSEQAATPPV-------SNDST---
RAQRGSSVPVVL-ERTRSTV-SSPTHDLKV--G-SKSRSLPCVSS----------QTAKA
PATLQQRR--G--LRNSGAHCGCCREGTRNCHRRPA--------VVSAALAEKFNLDMSK
EESQQLVLKYDLKNNGRFAYCDFIQSCVLLLKAKETALMHRMRIQNAQKMVGAGAAP---
-------------GLRPVRRAFLG-------------GLQVLRQYSINLSEEEFFHVLEY
YDKTLSSRVAYNDFLRAFLQ----------------------------------------
---------------

-----EL-----------PPGQ-------------DRIMSSSSFRDLRPQTRGITFAGRP
QSALSRS-LSRSSRSSVQSSLAIYPCEVSSVKSVRDPTLTPL--EIEGIIYRRVNENEED
VTNAFLTLDTEQNFTVTRGEFYRVLQNF

PF08976 // ENSGT00390000013629_0_Domain_0 (149, 181)

ILPLTESQFNELLEKIPVNNNGTIPYLDFLAK

ENSGT00390000013629_0_Linker_0_1 (181, 228)

FL-RTSSSATCARSVKRSW-SCSQANQVLSLNELEIRLKNTVSKNLK

PF00036 // ENSGT00390000013629_0_Domain_1 (228, 256)

NVVRSCRLFDYNQ
NGQIQKQELRRILEN

ENSGT00390000013629_0_Linker_1_2 (256, 399)

CCFKMKTA-EFEK--------------------------------
-------LWNRYCIGKKNTLDYRELLRNL-GVNVELHNKPTAENVASAALNWEAVQREQQ
KEKNCRPP-PPLKELSAEDYTIDDIEAALRKKISASYP

PF00036 // ENSGT00390000013629_0_Domain_2 (399, 427)

NLVKAFRAFDGSHSGYVSAEAL
QSVINNFIFPLPNGTFQKLMNRLAIKCTDRIGWEQFLRRFQGPE----SMANGQTIPMKP
NHRVNPVRGESPVVSSEHILQKLQRHFQDAYPSLKQAFLVL-DEGRKGRISRKELRRIVD
CMMFR-VTDA

PF00036 // ENSGT00390000013629_0_Domain_4 (551, 579)

QFKELMIILDPQHTGFISYLQFLDLFEDKESVSGHKWLHNMRTPLKETPV
TLEWEKMGNILCEKIEHNWADFSKAMKSCDSAGCGMVDKDQFKRILQSFCPPLSDRHYN-
-MLCEQYNDGANGYISYMDFLRNVGVCTSAAGDLNGV--STEIV-HGS-QLREELRQDDL
SARYEPIESQ-ATQLVKKMPVEEVIGKLKDCVIGQEFSPRESFLAFAKQHKGRISKKDFR
KVLREHEIHLDEDQFKRLTEKLGFTK-EELSYLDFVSLFEGFTDP--TGNGPGAALD---
TGSNHHVNDTKFHYMSAEDCLAQLRD---KLQQGYG

PF00036 // ENSGT00390000013629_0_Domain_6 (877, 905)

DLYSAFYKIDSNRDGLVTMHDFRH
LLDS

ENSGT00390000013629_0_Linker_6_7 (905, 984)

FMFIIKPQEFQRLLGLLGLNLSSTLNYKEFLHLFQKPQSPVYPPWLQSSHSPKQSM
GGEDLACEQAHYYLVTKAQGRWH

PF00036 // ENSGT00390000013629_0_Domain_7 (984, 1012)

DMAKTFCEIDSEGNGIVQKKDLRNVLFR

ENSGT00390000013629_0_Linker_7_8 (1012, 1020)

FYLPIHPK

PF00036 // ENSGT00390000013629_0_Domain_8 (1020, 1047)

E
FEKLWGRYDPEGKGFLTH----NEFL

ENSGT00390000013629_0_Linker_8_9 (1047, 1116)

EKLGISFASGDSGPSKQITEDNRACLEGHYNNQL
KIQEEMDAFHKHQTKALDMKDIEQQIKDKFRDYYH

PF00036 // ENSGT00390000013629_0_Domain_9 (1116, 1144)

DFSAAFAKIDRNKDGQISVHDLRAM
LQS

ENSGT00390000013629_0_Linker_9_10 (1144, 1232)

LNFHLDDEQFANLLY----RLRIKVTD-NKLSYPDFLRMIDD-GRASKYGQ-RQRP-
---VSAAETPPKLSLQKVLLKLKEAVVSSHD

PF00036 // ENSGT00390000013629_0_Domain_10 (1232, 1260)

ALYKAFSSFDRDGTGTIKASELHQILDSF
CFKLSDRQFGYLLSKLPLGEEQTIDWKAFLHHFSTSHPEPHRGLQTLNQSFYLQLPIAG-
--LAAGQVIQDCIRSIIIST-----IMCCPGFNPCSLAATDLIKGENYLAL---GFQLLA
NKASTVGGTGPSSSWVERVQH-ATRXPYEKTAGDQ-SEFIYKPA----------------
SALAGNHTPPESQAGIRRPK-TAPAIL-------NKPKTDTQRP-------------KTA
GASSRLVNCEQIEARLRGSLQKVWQ

PF00036 // ENSGT00390000013629_0_Domain_14 (1526, 1554)

EVLRACRDYDPERTGEITTNDFSGVLKQ

ENSGT00390000013629_0_Linker_14_16 (1554, 1637)

FNAETNE
EELERLTVKYDSRNNGKFSYADFFRNIMLGPKPLEKSPLHRMKVQKTRVPISTGPDGPCF
LNAMMRIQPKVLDCWR

PF00036 // ENSGT00390000013629_0_Domain_16 (1637, 1665)

PMRRAFLSFDEARTGFISVQEFKQVLRKSGLNLSEDEFFHILGF
FDKDLKAKVSYNDFLRAFLR----------------------------------------
---------------

----------------------------------MCKMAIIPDWHTWHPRA-RKFTYLRP
HSSPCRV-YSRNGFQN-----MFRPSSS--TTAVANPILSFL--DVKRILFQKIADKGD

PF00036 // ENSGT00390000013629_0_Domain_0 (120, 148)

E
LKKAFQLLDTGQNQTVSKSELRRAITTFLLPLTREQFQDVLAQIPLTSSGAVPYLEFLSR
FG-GSNVNVN---VMKXXX--XXXXXXXXXXXXXXXXXXXXIFENIK

PF00036 // ENSGT00390000013629_0_Domain_1 (228, 256)

TVFKALKLIDVNE
TGLVQAHDLRRVLETFCLKMSND-EYKL--------------------------------
-------XXXXXXXXXXXXXXXXXXX-XX-XXXXXXXXXXXXXXX--XXVSGG-NQQVKN
FKKECLSR-SKSTEDIWKKYNLDEIEKTFCQELSKSYEKVEKALSAGDPAKGGYVSLNYL
KVVLDTFVCQLPRRIFIQLMKXXXXXXXXXXXXXXXXXXXX--------XXXXXXXXXXX
XXX-XX---XXNHSCKENIIVKLRRYAGGHLTSLKEALLIP-STDLGGHIRRKELQNILN
CMAFK-ISDSEFKELMQMLDPRETGLVNVNSFFEL-LEEENLKMRK--RSPCT-DNNALL
LAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-
--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXX-XXXXXX
XXXTKPTEDK--TT----LTKEEVIEKLKNCIQQQDPTFRKRFLDVSKEPNGKINEHEFK
KXXXXXXXPMDEEQYALLTKKIGYEK-EGMSYLDFATGFED-----TKMSWPEAATP-QT
VVFTRS--NLDTRFLTAEECLQLFPQ---RLKESFQDPYS

PF00036 // ENSGT00390000013629_0_Domain_6 (881, 905)

AFFKIDSDRDGIINMHDLHR
LLLRLLLNLKDEEFERFLSLLGLRLSVTLNFREFRNLCEKGVFRT-DEAPQRLVRPKQKL
TDSELACEQAHQYLVTKAKNRWADLSKNFIETDNEGNGILRRRDIKNALYGFDIPLTPR

PF00036 // ENSGT00390000013629_0_Domain_8 (1020, 1047)

E
FEKLWMRYDTEGRGHITY----QEFL

ENSGT00390000013629_0_Linker_8_9 (1047, 1116)

QKLGISYSAAVHRPYA----EGYFNFMGHFTKPQ
QVQEEVRELQQNT-------GKALPGRDQLQDHYQ

PF00036 // ENSGT00390000013629_0_Domain_9 (1116, 1144)

DIIKALTKLDKSKNGCISISKMQKA
LQERCCSLKEEELTHLLN----SWGISRHD-NQVNYLDFLRAVYN-SKSPRPQP-TEKK-
---ESQPINFATLNPEEVVKNIQEVVASSHQALLKAFSTLDKEDTF--------------
---IKANQYHYFLRKLRIHLTPYINWKYFLQNFSCFLEETAVEWA---EKMPKGPPPVS-
PKEKARRDLVAHLRKAVAS----RYGAIAREFENFDTMKTHTASRDEFRAICTRH

PF08976 // ENSGT00390000013629_0_Domain_12 (1376, 1525)

VQILT
D-------EQFDRLWSEMPVDAKGKLKYQDFLSRFSSGKAETLLA-------TSDSG---
RAQRGSSVPPGS-GGIRSVA-SSPTGDLQE--G-PKSRSHPCTPA----------STAPW
PRTLPLQNCEPIENKLRKKIQGCW

ENSGT00390000013629_0_Linker_12_14 (1525, 1526)

R

PF00036 // ENSGT00390000013629_0_Domain_14 (1526, 1554)

ELLKECKEKDVNKQGEITTFEFLALVEK

ENSGT00390000013629_0_Linker_14_16 (1554, 1637)

FNLDVSK
EECQQLIVKYDLKNNGKFAYCDFIQSCVLLLKAKETSLMQRMKIQNMHKMKEAGAETSSF
YSALLRIQPQILHCWR

PF00036 // ENSGT00390000013629_0_Domain_16 (1637, 1665)

PMRRTFKTYDEGGTGFLNVADFRKVLRQYSINLSEEEFFHILEY
YDKTLSSKISYNDFLRAFLQ----------------------------------------
---------------

-------------------------------------MAVVPDWHIMCPYT-RKFTHSRP
HSSPCRV-YSRSAFQN-----MFRPSSS---TTVANPILSSL--DVKRILFQKITER

PF08976 // ENSGT00390000013629_0_Domain_0 (118, 182)

GDE
LKRAFQLLDTARSMTVTKSELRRVITAFLLPLTREQFQDVLAQIPLTSSGAVPYLVFLSR
FG-GIDLSIN---VIKRGG--ENEMNGCRTLKELEAQVGEKIFKNIKTVIKALTLIDVNT
TGLVQPHELRRVLETFCLKMKDE-EYKK--------------------------------
-------FAQHYDIDKDAAVDYKVFLKNL-SSNNDLNLKYNTGSQ---EVLWE-NQRVKS
SKREEPPS-SAVSDNVWKNYSLDEIETAFCLELSKCYEKVEKALSAGDPCTSGYVSLNYL
KIVLDTFVYRLPRRVFIQLMKRFGLKTTTKVNWKQFLTSFYEPQ----YE-GSNKAPLTK
RNS-IN---FRNQVHKENIITKLFRHE-DHYTSLKKALLLI-KSK

PF13833 // ENSGT00390000013629_0_Domain_4 (526, 575)

PDGQITGQELQRVLN
CMVVN-ISDSEFRELMRVLDPGCTGCVSVSKFTEL-IE-ENPKLHK--IPACK-DTKMPL
FLAWDSVEEIIHDSIAKNPSAFCNMLRSYDLGDTGLIGRNNFKKIMRVFCPFLTTEHLV-
-KLCSKFQDIASGRILYKKLLACLGINRPPTVSPVSV--PKGQLLNEQLQKEE-QPLPDL
SERAKPAESQ--GAMARNMTKEEVIEKLKSCIRQQDPALRKRFLDFTKEPDGKINMHDFK
KVLEANGMPMDDDQYALLTTKLGYKK-EGMSYLDFAAGFKD-----PKMNGAEVTPP-QT
PALPKG--DVDSFFVTAEECLRQFPR---RLKEFFRDPYAAFFKMDTDRDGILTMYDLHR
LLQHLLFNLKDEEFERLLGLLGLRLSVTLNFREFRSLCEKRSFCTDDDAPQRLLRPKQKV
ADSELACEQAHQYLVTKAKTRWSDLSKNFIETDSEGNGILRRRDVKNALYGFDIPLTPRE
FEKLWMRYDSEGRGHITY----QEFLQKLGINYSADVHRPFV----EEYLNFMGHFTKPQ
QVQEELKELQQSREK-------ATAARDKLKDHDQDISKALAKLDKSKTGYISLCRLQKL
LQECGCSLKEEELIDLLN----SWGIGWHN-NSINYLDFLRAVEN-SKPTRPQS-QEKE-
---ESVPINFAALNPEEVLKNIQEVVAASSLALSMAFSALDKEDTGFVKASDFGQVLKDF
CYKLTDNQYHYFLRKLRLHLTPYINWKYFLQNFSSYVEETAVEWA---EKMPRGPRPLS-
PKE

PF08976 // ENSGT00390000013629_0_Domain_11 (1324, 1444)

MANQELLARLHKAVTS----HYHAIAQEFENFDTMKTNTASRDEFRSICTRHVQVLT
D-------EQFDRLWEEMPVNSKGRLKYLDFLSSFNADKPATPPA-------TGDSA---
KAQRGSSVPEVS-DRGRSAGSS-PTRDPKA--G-PKSRSHPCTPS----------SV---
SGTPPLQNCEPIETKLRKKVQGCWRELLRECKERDPNRQGEIPGPEFLALVEKFNLDITR
DECQQLLVKYDLKNNGKFAYCSFMQSCVLLLKAKETSLMQRMKIQNANKMKEAGAETCSF
YSALLRIQPKIVHCWRPMRRTFKAYDEGG

PF13833 // ENSGT00390000013629_0_Domain_17 (1650, 1698)

TGFLSVADFRKVLRQYSINLSEEEFFHILEY
YDKTLSSKISYNDFLRAFLQ----------------------------------------
---------------

----------------------------------MCKMAIIPDWLRSHSRA-RKFTHSRP
HSSPCRV-YSRNASPN-----MFSSCS---STAVANPTLSSL--DVKRILFQKI

PF08976 // ENSGT00390000013629_0_Domain_0 (115, 188)

TDRGDE
LKKAFQLLDTGQNSTVSKSELRRIITDFLMPLTREQFQDVLAQIPLSISGTVPYLDFLSR
FG-GIDL

ENSGT00390000013629_0_Linker_0_1 (188, 230)

YIN---GIKRGD--ENEMNGCRTLKELEIQVGEKVFKNIKTV

PF13202 // ENSGT00390000013629_0_Domain_1 (230, 253)

MKAFKLIDVNK
TGLVQPQELRRVLETFCLKLRDE-EYEK--------------------------------
-------FSKHYNVHKDTAVDYNVFLKNL-SINNDLNLRYFVGNQ---EVSLE-DQQAKN
SKKECLLS-SASSEDIWRNYSLDEIERNFCLELSKSYEKIEKALSAGDPCKSGYVSFNYL
KIVLDTFVYQLPRRIFIQLMKRFGLKATTKINWKQFLTSFHEHQ----GLEISNKGSLTK
RNS-IN---FRNESHKENIITKLFRHTEDRSASLKKALLII-NTK

PF13833 // ENSGT00390000013629_0_Domain_4 (526, 580)

PDGLITREEFRHILN
CVAVK-LSNLEFKELMQTLDPGDTGVVNTSMLIDL-VE-ENSRMRK--KSPCT-DTKTPL
LLAWDSVEEVVHDTITKNLRAFYNMLCSYDLGDTGLIGRNNFKKIMHVFCPFLTNAHFI-
-KLCSKFQDIASGRIFYKKLLAHIGIDGPPTVSPVLV--PKDQLLSEHLRKDE-QQQPDL
SKRTKATGDQ--TTPTKKMTKEEVIEKLKNCIQQQDPAFKRRFLDFSKEPNGKINMHDFK
KVLEDTGMPMDDDQYALLATKIGFEK-EGMSYLDFAAGFED-----PPMRAPEATPPLQP
PTPSKS--YVNSHFITAEECLKLFPR---RLKESFRDPYSAFF

PF13202 // ENSGT00390000013629_0_Domain_6 (884, 901)

KIDTDRDGIINMHDLHR
LLLHLLLNLKDQEFERFLSFLGLRLSVTLNFREFRNLCEKRPLRT-DEAPQRLIRPKQKV
ADTELACEQAHQYLVTKAKSRWSDLSKHFIETDNEGNGILRRRDIKNALYGFDIPLTPRE
FEKLWARYDTEGRGHITY----QEFLQKLGINYSPAVHRPCM----EDHFNFMGHFTKPQ
QLQEEMKELQQGT-------GKAVPARDKLMDHYQDISKALTKIDKSKTNYISICKMQKV
LEECGCFLTEEELTHLLN----SWGVSRLD-NSINYLDLLRALEN-SKSTGAQP-KEKE-
---ESTPIDFATLNPQEVVRRIQEVVESSHPALSTAFSALDKEDTGFVKATEFGQVLKDF
CYNLTDNQYHYFLRKLRIHLAPYINWKYFLQNLSCFLEETADEWA---EKMPKSSPPSS-
PKA

PF08976 // ENSGT00390000013629_0_Domain_11 (1324, 1391)

VASRDLLARLHKAVTS----HYHAIAQDCENFDTMKTNTISRDEFRAICTRHVQILT
D-------EQVRNPCQPSPYTPSAERQP-GPWPVYRV-----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------

----------------------------------MCKMAIIPDWLRLHPHT-RKFTHSRP
HSSPCRV-YSRNGSPN-----MFRSSS---PTAVANPTLSSL--DVKRILFQKITD

PF08976 // ENSGT00390000013629_0_Domain_0 (117, 199)

RGDE
LQKAFQLLDTGQNLTVSKSELRRIITDFLMPLTREQFQDVLAQIPLSTSGTVPYLAFLSR
FG-GIDLYIN---GIKRG

ENSGT00390000013629_0_Linker_0_1 (199, 230)

D--GNEMNCCRTLRELEIQVGEKVFKNVKTV

PF13202 // ENSGT00390000013629_0_Domain_1 (230, 253)

MKAFKLIDVNK
TGLVQPQELRRVLETFCLKLRDE-EYEK--------------------------------
-------FSKHYNIHNDTAVDYNVFLKNL-SINNDLNLRYCTGNQ---EVSLE-NQQAKN
SKKERLLG-SASSEDIWRNYSLDEIERNFCLELSKSYEKIEKALSAGDPCKGGYVSFNYL
KIVLDTFVYQIPRRIFIQLMKRFGLKATTKINWKQFLTSFHEPQ----GLQVSNKGPVTK
GNS-IN---SRNESRKENIITKLFRCTEDGSASLKKALLII-NSKP

PF13833 // ENSGT00390000013629_0_Domain_4 (527, 578)

NGPITREEFRYILN
CVAVK-LSDSEFKELMQTLDPGDTGVVNTSMFIDL-IE-ENSRMRK--TSPCT-DAKTPF
LLAWDSVEEIVHDTITRNLQAFYNMLRSYDLGDTGLIGRNNFKKIMHVFCPFLTNAHFI-
-KLCSKIQDIGSGRIFYKKLLARVGIDGPPTVSPVLV--PKDQLLSEHLQKDE-QQQPDL
SERTKPTEDK--TTLTKKMTTEEVIEKFKKCIQQQDPAFKKRFLDFSKEPNGKINVHDFK
KVLEDTGMPMNDDQYALLTAKIGFEK-EGMSYLDFAAGFED-----PPVRLPETTPP-QP
PTPSKS--YVNSHFITAEECLKLFPR---RLKKSFRDPYSAFFKTDADRDGIINMHDLHR
LLLHLLLHLKDDEFERFLGLLGLRLSVTLNFREFRNLCEKRPWRT-DEAPQRLIRPKQKF
ADSELACEQAHQYLVTKAKNRWSDLSKNFLETDNEGNGILRRRDIKNALYGFDIPLTPRE
FEKLWARYDTEGKGHITY----QEFLQKLGINYSPAVHRPCA----EDYFNFMGHFTKPQ
QLQEEMKELQQST-------EKAVAARDKFMDRHQDISKAFTKIDKSKTNYISICKMQKV
LEECGCSLTEGELTHLLN----SWGVSRHD-NAINYPDFLRAVEN-SKSTGAQP-KGKE-
---ESMPINFATLNPQEVVRKIQEVVESSQLALSTAFSALDKEDTGFVKATEFGQVLKDF
CYKLTDNRYHYFLRKLRIHLTPYINWKYFLQNFSCFLEETADEWA---QKMPKGPPPTS-
PKA

PF08976 // ENSGT00390000013629_0_Domain_11 (1324, 1444)

MADRDILARLHKAVTS----CYHAITQEFEHFDTMKTNTISGEEFRAICNRHVQILT
D-------EQFDRLWNEMPVNAKGRLKYPDFLSRFSSETAATPMA-------TGDSA---
AAQRGSSVPNVS-EGTRSAL-SLPTQELRP--G-SKSQIHPCTPA----------STTVI
PGTPPLQNCDPIESRLRKRIQGCWRQLLKECKEKDVARQGDINASDFLALVEKFNLDISK
EECQQLIIKYDLKNNGKFAYCDFIQSCVLLLKAKESSLMRRMKIQNAHKMKEAGAETSSF
YSALLRIQPKIVHCWRPMRRTFKSCDEAGTGLLSIADFRTVLRQYSINLSEEEFFHILEY
YDKTLSSKISYNDFLRAFLQ----------------------------------------
---------------

--------MRRNGAKLNLAKVNSTKSGSTKARDLMNKMSIIPEWHSLYPNA-RKLPCSRP
HSSPCKT-Q-RTVFQD-----LCRPSSS--TTAIANPVLSYL--DIERILSQKISSRRDE
LKKVFQVLDRNHSQTVTKADLKRAITTFLIPLTKDQFQDLLAQIPISSMGNVPYLEFLSR
FGGGIDINIS---GIKRVN--ENEVDNRRTLKEV--QLTEKIFRNMRT

PF13202 // ENSGT00390000013629_0_Domain_1 (229, 253)

IRKVFQLIDVNN
TGTVQPQELRRVLETFCLKMKDE-DYKM--------------------------------
-------FLEQYSIDNTTAVDYNAFLKNL-SVKNDASFKYLLSNA--AELPRE-TQQGKN
GK--RPLD-TVSSEDLWKNYSLDDLEKTFCQEFSKSYEKIEKALSAGDPSKSGYISLNYL
KVVLDTFVYRLPRRIFIQLIRRFGLKTSTKINWKQFLTAIYERQ----RLEVSKTIPLKK
RSS-TE---ARNRSRKENIIKKLFKYSEERYTALKKTLLII-SSTPSGHITWEELRHILN
CMVAK-LNDSEFSELKQTFDPEGTGAVRVNSLLDV-LD-DSTKVRK--MSPST-DTKTPL
PVAWDSVEELVLDAITRNLQAFYSMLQSYDLGDTGTIGKNNFKKVMRVFCPYLSNEHLV-
-RLSSKFQEAGSGRMLYKKFLLSTGVGIPPPTPPLSP--PKVQL-SDHFQTEE-PGQR--
DERTQPSGDK--TVEINNRTKEEVIDSLKHRIQQKDPVFRKEFLSISKEPHVKINQEEFR
KVLERSGMPMNDCQYSMLASKLGFKTEEGMSYQDFTMGFED-----SMLSGLETVPL-QS
RTASRM--NMDEHFISAEECLRIFPK---KLKESFRDVYSAFF

PF13202 // ENSGT00390000013629_0_Domain_6 (884, 901)

RIDSDRDGIISMHDLHR
LLQYLQLNMIDLEFERFLSLLGLRLSVTLNFREFQNLCEKRPWKS-DEAPQRLIRCKQKV
ADSELACEQAHQYLIMKAKTRWADLSKNFIETDNEGNGILRRRDIKNSLYGFDIPLTPRE
FEKLWQTYDTEGRGYITY----QEFLHRLGIRYSPKVHRPYK----EDYFNFLGHFTKPK
QVQEEIQELQQITER------------EKLMDHYEEISKAFNAMEKSK--PVALCRVQKV
LQECGCPLKEEELISLLK----SLDVSVHS-NHIDPVEFLRALEI-SWASKARP-KEK--
EESS-LPVSFSRLTPDEVIKTMQDVVESSQPALVKAFSALDKEDTGFVKAMEFGDVLRSV
CQKLTDNQYHYFLRRLRLHLTPNIHWKYFLENFSSFQDETADEWA---ENMPKAPPPTS-
PK

PF08976 // ENSGT00390000013629_0_Domain_11 (1323, 1444)

ETAHRDIMARVQKAIAS----HYHTIVQEFENFDTLKSNTVSRDEFRSICTRHIQILT
D-------EQFDRLWSELPVNAKGRLKYQDFLSKLSIDRVPSPPMAAGD---SGEST---
VAQRGSSAPEIS-QGTRSNL-YSPPRDSRV--G-LKSRSHPCTPV---------------
-GTPPLQNCEPIESRLRKQIQGCWRELLRECKEKDKDKQGTISAAEFLALVDKFKLDISR
EESQQLIIKYDLKNNGKFAYCDFIQSCVLLLKAKETSLMRRMRIQNADKMKEAGMETPSF
YSALLRIQPKIVHCWRPM

PF13499 // ENSGT00390000013629_0_Domain_17 (1639, 1698)

RRSFKTYDENGTGLLSVADFRKVLRQYSINLSEEEFFHVLEY
YDKSLSSKISYNDFLRAFLQ----------------------------------------
---------------

--------MKGSE----------KK---SSHRELIRSVVNSVDLGTLQPVAAIVKADGRP
HSSPLNI-MAPNSGRS-----LDRPSSS---ICVVNPILSFA--DLDRIFFQKILKKEED
LKKAFNIIDSEQTLRVTKNQLRRVIEVYLLPLTRKQFNEVLSQIPLTSSGEVPYLEFLSR
FG-RLITNVN---TLKRVN---GKLCANRPLNQLECQLGEKIFKNVRGVIKAFKLFDCTQ
SGQIHPNGLRQVLENFCFKLRDE-EFEK--------------------------------
-------LWNRYSFGKESSLDYHMFLQNL-ATNINLNQKYNIGNK---D-------WRGK
PDNKYVFAFSSSLGEGWEDSSMDEIEAAFCREFGVSTSNIEKALSAFDTTKRGYVSLNYL
KIVVDNFVFPLPKDIFLQLLKRLGFKPTGKIAWKQFLRKCQTSA----IMENALTIPVKK
KKR-VN---GTEPTSKENILTKLCRHVDDDLSSLKKGLQMI-NLKQDGKITGKELRHVLN
CALWK-MNDLEYKELMQMLDPTGCGFVNYITFLYL-LEEEYSAMKKKRRNGLK-EEKIPQ
FLAWDSVEEVLHDTLSKSLQEFHAMLKSHDIGDTGIMSRNNLKKIIQTFCRYLSDEYLT-
-KFCDKFQDMISGGILYKKLLASIGITLPLRLSDNPVTVQSLQSLNGV------CRREDL
PERSKFSECR--NELVRPKTLEEVIENLKYWIQTQDTTFRDTFLEYSKHPLEKIGKDEFR
KVLEDNGMPMDDEQFGLLVKKIGFKN-EGLSYLDFAAGFE--DG---KPNGRESPVTPST
PPTAGPKSSFESHFTTAEDCLKNFPK---RIKEIYGDAYSAFYKTDTNHDGIINMADFRG
MLHHMLFTLKEEEYMRLLEAMGLKLGLTLNYREFRNLCEKRQFKK-DDPPQRLIRSKLKT
TDSELACDQAHSYLASEAKNRWHDLSKHFLETDNEGNGILRRRDIRNALYGFDIPITPRE
FEKLWMRFDPAQKGYVTY----QEFLARMGIEYLPSIHRPYT----VDHFNFMGHFTKQD
QMQEEAREFQQSLEM-------NKPFREKFKDHLQDLSQAFAKVDKHKNSFISMNDLQKV
LQEYQPNITEEEITMMLK----SWGIPYSD-NIVYYHEFLRALES-FKPSKSHS-KEKE-
---ESVQIPFSPLTPEQALKRMKDLVLANHNYFYKAFAVYDKEDTGIIKAAEFAQVIKDL
CFKLKDSQYTYVLKKLKLHLNSHINWKFFLRNFPCFCEETAAEWT---EKMQKASAPKA-
AKDPFLKDLLLRVRDIVTM----RFSNLLQEFTDIDCSRCCTTSKEEFRNICNRHF

PF08976 // ENSGT00390000013629_0_Domain_11 (1377, 1427)

QILN
D-------EQFEIFWNELPLNSEGRLKYQEFLCKFNMEKSLSPPLHGGPRQAPET--QHH
PGGRGGTAPRSP-GGFHARP----GPAPP-----DWSRKRSGDCE----------LHGLQ
DRRPPFAEL---------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------

----------------------------------MCKMAIIPDWQTSYPHT-GKLKNLRP
HSSPCRV-YSRNSFQN-----MFRPSSS--TTAIANPILSFL--DVKRLLFQKITDKGYA

PF13499 // ENSGT00390000013629_0_Domain_0 (121, 181)

LKKAFELLDTSHNMTVSKNELRRIITTFLMPLTREQFQDVLAQIPLTSSGAIPYLEFLSW
FG-GMDLSIN---VIQRGG--GNEMSCSRTVKELEKQIGEKIFRNIKTIFKAFKLIDVSK
TGLIQSCELRKVLETFCLKMKDD-EYKK--------------------------------
-------FAKHYNIDKDTAVDYNVFLKNL-SANNDLNLRYYMGNQ---DISWK-NQPVQN
SKGECLHS-SGSSEDVWKNYNLDEIERTFCQELPKCYEKVEKALSAGDPSKSGYVSLNYL
KIVLDTFVYRLPRRIFIQLMKRFGLKTTTKINWKQFLTSLYEPQ----WLEVNNTVPPTK
RNR-IT---SRDQSCKENIITKLSRQE-DHYTSLKKALLIA-NTKPDGQITGKELRYILN
CMVVK-ISDSEFKELMQMLDPGDTGWVNIYTLIEL-LE-ETPKIQK--LSSSA-DTKAPL
LLAWDSVEEIIQDSIARNLQAFYKMLRSYDLGDTGLIGRNNFKKIMRIFCPFLTIEHLL-
-KLCSRFQDIASGRILYKKFLASMGMSGPPPPSPVIT--PKDQLLSDHFQREE-QRKLDL
SERTKPVEDR--STSTKKMTKDEAIEKLKNCIQQRDPAFKKFFLDYSKELTGKIHVRDFK
KVLEASGMPMDDDQYALLTAKIGYKR-EGMSYLDFAAGFED-----AKMSRPEVIPL-QT
PVLSKT--NLDRYFITAEECLKQFPQ---RLKEAFRDPYSAFFKIDTDRDGIINMHDLHR
LLLHLLFNLKDKEFERFLGLLGLRLSVTLNFREFRNLCEKRALRT-DDAPQRLIRPKQKV
ADSELACEQAHQYLVTKAKTRWSDLSKNFIETDNEGNGILRRRDIKNALYGFDIPLTPRE
FEKLWMSYDTEGRGHITY----QEFLQKLGINYSADIHRPYA----EDYFNFMGHFTKPQ
QMQEEARQLEQSVDR-------TAPVRDKLKDHYQDISKALTKLDKSKNGYLSMCKMQKV
LQELGCSLKEEELTNLLN----SWEIKWHD-NSINYLDFLKAVES-SKPTRPQP-KKKE-
---ESVPISFSTLNPEEVVKNIQEVVASSDMALSTAFSALDKEDTGFVKASDFGQVLKDF
CYKLTDNQYHYFLRKLKIHLTPHINWKYFLQNFSSFSEETAAEWA---EKMPKGPPPTSP
PKETANQELLAQLHKAVGS----HYHAIAQEFDNFDTMKTYTASKDEFRAICARH

PF08976 // ENSGT00390000013629_0_Domain_12 (1376, 1525)

VQILT
D-------EQFDRLWSKMPVNAKGRLKYLDLLSMFSSKRAPTPLT-------TGSSA---
KAQRGSSVPEIS-DGSRPAV-SSPIHDLKA--G-LKAQSHPCTPA----------SASSA
PGTLPLQNCEPIESKLQKKIQGCW

ENSGT00390000013629_0_Linker_12_15 (1525, 1539)

REFLKECKEKDVNK

PF13833 // ENSGT00390000013629_0_Domain_15 (1539, 1577)

QGQVTTAEFLALVEKFNLDISK
EECQQLIVKYDLKNNG

ENSGT00390000013629_0_Linker_15_17 (1577, 1639)

KFAYCNFIQSCVLLLKAKETSLMQRMKIQNAHKMKESGAETSSF
YSALLRIQPKIVHCWRPM

PF13499 // ENSGT00390000013629_0_Domain_17 (1639, 1697)

RRTFKAYDEGGTGLLSVADFRKVLRQYSINLSEEEFFHILEY
YDKTLSSKISYNDFLRAFLQRESLSHLSLTMSWTSVSLLTNRAWKRKTSTFTVEKAGRHH
HHHVLKTGIHSGTSR

----------------------------------MCKMAIIPDWLRSHSRA-RKFTHSRP
HSSPCRA-YSRNGSPN-----MFRSCS---PTAVANPTLSSL--DVKRILFQNITD

PF08976 // ENSGT00390000013629_0_Domain_0 (117, 204)

RGDE
LKKVFQLLDTGQNSTVSKSELRRIITDFLMPLTREQFQDVLAQIPLSTSGTVPYLDFLSR
FG-GIDLHIN---GIKRGD--EN

ENSGT00390000013629_0_Linker_0_1 (204, 230)

ETNCCRTLRELEIQVGEKVFKNIKTV

PF13202 // ENSGT00390000013629_0_Domain_1 (230, 253)

MKAFKLIDVNK
TGLVQPQELRRVLETFCLKLRDE-EYEK--------------------------------
-------FSKHYNVHKDTAVDYNVFLKNL-SINNDLNLKYFVGNQ---EVSLE-DQQAKN
SKKERLLS-SASSEDIWRNYSLDEIERNFCLELSKSYEKIEKALSAGDPCKSGYVSFNYL
KIVLDTFVYQLPRRIFIQLMKRFGLKATTKISWKQFLTSFHEHQ----RLEINNKGSLTK
RNS-ID---SRNEPHKENIITKLFRHTEDRPASLKKALLII-NTK

PF13833 // ENSGT00390000013629_0_Domain_4 (526, 580)

PDGLITREEFRHILN
CVAVK-LSNLEFKELMQTLDPGDTGVVNTSMLIDL-VE-ENSRMRK--KSPCT-DTKTPL
LLAWDSVEEVVHDTIAKNLQAFYNMLCSYDRGDTGLIGRNNFKKIMHVFCPFLTNAHFI-
-KLCSKFQDIASGRIFYKKLLAHVGIDGPPTVSPVLI--PKDQLSNEHLQKDE-QQQPGL
SKRTKATGDQ--TTPTKKMTKEEVIEKLKNCIQQQDAAFKRRFLDFSKEPNGKINMHDFK
KVLEDTGMPMDDDQYALLATKIGFEK-EGMSYLDFAAGFED-----PPMRAPEARPPLQP
PTPSES--YVDSHFITAEECLKLFPR---RLKESFRDPYSAFF

PF13202 // ENSGT00390000013629_0_Domain_6 (884, 901)

KIDTDRDGIISMHDLHR
LLLHLLLNLKDQEFERFLGFLGLRLSVTLNFREFRNLCEKRPLRT-DEAPQRLVRPKQKV
ADSELACEQAHQYLVTKAKSRWSDLSKNFLETDNEGNGILRRRDVKNALYGFDIPLTPRE
FEKLWARYDTEGRGHITY----QEFLQKLGINYSPAIHRPCM----EDYFNFMGHFTKPQ
QLQEEMKELQQGT-------EKSVPAGDKLMDHYQDVSKALTKIDKSKTNYISICKMQKV
LEECGCSLTEEELTHLLD----SWGVSRRE-NSVNCLDLLSALES-RTS------GEKG-
---ASAPVNFATLTPQEAVRGVRDVVESARPALSAAFSALDKEDTGFVKATEFGQVLKDF
CYNLTDNQYHYFLRKLRIHLAPSINWKYFLQNLSCFFEETADEWA---EKMPKSSPPSS-
PKT

PF08976 // ENSGT00390000013629_0_Domain_11 (1324, 1437)

VANRDLLARLHKAVTS----HYHAIAQDCENFDTMKTNTISRDEFRAICTRHVQILT
D-------EQFDRLWNEMPVNAKGRLKCPDFLSRFSSETPATPMA-------SGDSV---
AAQGGSSVPDVS-ESTRSAL-SSPTRELRP--E-SKSRSHPCTPA----------NTAAI
PGTPPLQNCDPIESRLRKRIQGCWRQLLKECKEKDVGRQGSISTSEFLALVEKFSLDISK
EECQQLVIKYDLKNNGKFAYCDFIQSCVLLLKAKETSLMQRLRIQNAHKMKEAGAETSSF
YSALLRIQPKIVHCWRPMRRTFKSYDEAG

PF13833 // ENSGT00390000013629_0_Domain_17 (1650, 1698)

TGLLSVADFRTVLRQFGINLSEEEFFHILEY
YDKTLSSKISYNDFLRAFLQ----------------------------------------
---------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------VRK--MSP-S-DTKASL
PLAWDSVEEMVLDSITRNLQNFYGMLQSYDLGDTGTIARNNFKKVIRIFCPYLSNEHYV-
-KLSSKFQDTTSGRILYKKLLMSIGINVPTSTFPLSV--PKDQL-SEQLQNEE-QGQPDL
AERTQSMRDK--M---TDTTIEEVIDKLKQFIQEQDPVFKKHFLSISQQPDAKIGLEDFR
KVLEESGMPMNDSQYAILTSKIGYKK-EGMSYQDFTSGFEE-----GKLSGLETVPL-QP
RTSSKT--NLDEYFISAEECLRLFPK---KLKELYRDPYSAFFKVDTDMDGLINMNDLHK
LLQQLQLYMKDSEYERFLGLLGLRLSLTLNFREFENLCEQKPWKS-DEAPQRLIRYKQRV
ADSELACEQAHQYLMVKAKTRWADLSKNFIETDNEGNGILRRRDIKNALYGFDIPLTPRE
FEKLWQNYDIEGRGYITY----QEFLQRLGIRYSSKTHRPYK----EDYFNFLGHFTKPK
QIQEEMQELQQTIDR------------EKLMDHYEEISKSLNMLEKSKTGAVSLCKVQKV
LQDCGYPLKEEELIYLLK----SLSISVHN-NCIDPLDFLRALET-NKTSKAPP-KEKEK
EESIPPPINFSKLNPEEVVKSVQVVVDASQPALFKAFSAIDKEDTGFVKAMDFGDVLKSF
CQKLTDNQYHYFLRKLKIHLTPNIHWKYFLENFDSFLEETADEWA---EKMPKVLAPTA-
PKE

PF08976 // ENSGT00390000013629_0_Domain_11 (1324, 1444)

MANRDILTRVHKAVAS----HYHVIAQEFENFDTTKSNTVSRDEFRSVCTRHVQILT
D-------EQFDRLWGEMPVNAKGRLKYQDFLSRFSTDREPSPPMAAGD---SGDST---
MAQRGSSAPDVS-QATRSTL-CSPPRDSKA--G-LKSRSHPCTPV---------------
-GTPPLQNCEPIESKLRKQIQGCWRELLKECKEKDSDKQGSITAAEFLAIVEKFKLDISK
EESQQLIVKYDLKDNGKFAYCDFIQSCVLLLKAKETSLMRRMRIQNADKMKEAGAETQSF
YSALLRIQPKIVHCWRPM

PF13499 // ENSGT00390000013629_0_Domain_17 (1639, 1698)

RRTFKAYDENGTGLLSVADFRKVLRQYSINLSEEEFFHVLEY
YDKSLSSKISYNDFLRAFLQ----------------------------------------
---------------

----------------------------------TSKMATIPVWHTLCPHV-QKFKNLRP
CTSSFRV-CSRNGFQN-----TSRSSST---TSVANPILSSL--DVKRILFQKITDKGDE
LVKAFLLLDPSYSMTVSKSELRRVINTFLLTLTREQFQDVLAEIHLTSAGAVPYLQFLSR
FG-GMDLNVN---LIKRCS--GGEVNGGRTLKELETLVGEKIYKNMK

PF00036 // ENSGT00390000013629_0_Domain_1 (228, 256)

AVVRALNLIDVNR
TGRMQPKELRRVLETFCLRMTEE-EYRK--------------------------------
-------FAEHYSINTDASVDYNAFLKSL-SINNNLNLKYYLGDQ---GASGE-NQQAKT
ASRDCVFRCSDAPESHWEDRSLDEIGRAFCQELSKCREKVEKALSAGDPSKCGYISLNYL
KIVLDSFVFQLPRRVFISLMKRFGLRTTNRIYWKQFLTLLHDPQ----WLEAPGSGPPAK
KDS-TS---PRNQCCEENIITKLFGRE-DHYTLLRKTLLMV-SSKVNGRIKGQELQHTIN
SLVVK-LSDSEFKELMRTLDPGDSGLVDIYRFLEL-LEESRGKMGK--PSSGG-DAQASQ
LLAWDLVEGMVRDSISRNLLAFYDLLCSYDLGGTGLIGANNFKKVMHIFCPCLTTEHLA-
-TLCSKFKDSASGKVLYKNLLASMGVQGLPAARPANA--MKDRPPREHGQKG---PPPES
AERAKPTEDK--STWTKTVTKDEAVEKLRHWVQQQDPAFKKQFLNFSKDLDGRVNWCNFR
KVLENNGMPMDDDQYAL-TATIGYKK-EGMNYLDLAAGFEG-----PRDSGPHSPPP-PL
PPPPSVPVLSVSHVVGGIEVLARGPGVGGHGQAARE

PF00036 // ENSGT00390000013629_0_Domain_6 (877, 905)

NLFAAFFRMDTNRDGIVSMQDLHR
LLEHLLFNLRDDQFERLVALLGLRLSVTLNFREFQNLFEETPPTT-DDPPQRLIRQKQKV
TDSELACEQAHQYLVTKAKNRWTDLSKNFTETDHEGAGILRRRDIKNALYGFDVPLTPR

PF00036 // ENSGT00390000013629_0_Domain_8 (1020, 1052)

E
LEKLWMRYDTKGRGHITY----PEFLHQLGI

ENSGT00390000013629_0_Linker_8_9 (1052, 1116)

TYSADVHRPYA----EDHSNFMGHFMKPP
PPEPPRKERPGSSGS------LPAAPGEKLKDRSE

PF00036 // ENSGT00390000013629_0_Domain_9 (1116, 1144)

DIRKALTKLDTCGSGSVSLCQLQRA
LRDSGCPLKEAELAALLG----SLGISWQN-NSINYLDFLRAVED-GKPSGAEP-KESE-
---AGVQVNFAKLSPEEVLKNVQKVVAASGPALATAFSAVDREDTGFLKASDFGQVLKDF
CYKLTDNQFHYFLRKLRLHLTPCIGWKYFLQSFGGFLEEVS-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------

----------------------------------MCKTAVLPECHTSSPHR-AECTNSRP
HSSPCRV-YSRSDFEN-----MFRPSS---TTDIANPILSFL--DIKRILFKKITNKGD

PF00036 // ENSGT00390000013629_0_Domain_0 (120, 148)

E
LKKAFQLLDISHNMTVSKNELRRIITTFLLPLTREQFQDVLAQIPLTSSGAVPYLEFLSR
FG-GIDPNIN---VIKXXX--XXXXXXXXXXXXXXXXXXXXIFKNIK

PF00036 // ENSGT00390000013629_0_Domain_1 (228, 256)

TIIKALKLIDANK
AGLIQLHELRRVLETFCLKMEDD-EFKK--------------------------------
-------FAQQYNIDKDTTVDYIVFLKNL-SIINNLNLRYSVGNQ---EVSWE-NLQVKN
FRREHLSS-SDSSDSVWKDFSLDEIERTFCQEXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXFGLKTTRKVNWKQFLKLLYEPK----RLEVNRTIPLTK
KNS-AN---SRNQSRKENIVTKLFRHDD--HASLRNVLLTL-NAEPKRQITREDLRHIIN
CTVVK-ISDSEFKELMQALDPGCTGLVDVSTFIEL-LE-ENPKVGR--LPSST-DAKAPL
LLAWDSVDEIVQDAIARNLLPFNNMLQSYDLADTGLVGRNNFRKIMRIFCPFLPMEQLS-
-KVCSKFQDTASGRILYKNFLASIGLNGPPTVPPVLA--PKDQPLSEHFQKEG-PWPLDL
SERSKPTEDKNKSTLTKNMTKGEVLEKLKNCVQQQDPAFRKRFLDFGKELDGKVNRPHFR
KVLENNRTAMENDPYAQPTAKVGRKR-EGLSYREIAAGFEG-----TKMDGPELTPP-QT
PVLSKN--SADGYFMTAEECLKLFPQ---RLKESFRDPYAAFFQTDGDRDGIVSMLDLHR
LLQRLLFNLKDAEFERFLGLLGLRLSVTLNFREFRNLLERRPFRT-DDAPQRLIRPKQKV
TDSELACEQAHQYLVTKAKNRWSDLSKNFIETDNEGNGILRRRDVKNALYGFDIPLTPR

PF00036 // ENSGT00390000013629_0_Domain_8 (1020, 1047)

E
FEKLWMSYDTEGRGHITY----QEFLQKLGINYSEDVHRPYV----EDHFNFMGHFTKPQ
QVQEEVRELQQSA-------EKTVPAXXXXXXXXXXXXXXXXXXXXXXXXXXSMCRMQKV
LQDCGCSLKEEELTQLLH----SWGISLQN-NSINYLDFLRAMEN-SKL-STQP-KEEE-
---EAVPIDFATLNPEEVLKNVQKVVASCGPALSTAFSALDKEDTGFVKSSDFGQVLKDF
CYKLADNQYHYFLRKLRIHLSPYINWKYFLQNFNCFLEETAVEWA---EKMPKGPPPEC-
PKDAANLEILALLHKAVTS----RYHAIAQEFENFDTMKTNTASRDEFRAICTRH

PF08976 // ENSGT00390000013629_0_Domain_12 (1376, 1525)

VQILT
D-------EQFDRLWSEMPINAKGRLRYPDFLSRFGSEKVATPPA-------TGDSA---
KAHRGSSVPEVS-DGNRSAA-SSPTRDLKA--A-TKQRSHPCTPA----------GTAAL
PGTPPLQNLEPVENKLRKKIQGCWRQFLKECKAKDVHKHGEITASEFLALVEKFNLDISK
EERQQLIVKYDLRDNGKFAYCDFIQSCVLLLKAKETSLMQRMKIQNAHKMKEAGPETSSF
YSALLRIQPQIVHCWRPMRRAFKASDEGGTGLVGVADFRKVLRQHSINLSEEELFHILEY
YDKSLSAKISYNDFLRAFLQ----------------------------------------
---------------

------------------------------------------------------------
-------------------------------TEIANPVLSFL--DIKRILFK-ITDRGDE
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXIPLTSSGTVSYSDFLNR
FG-GIDLNIH---VFKRASETENEKNCCRTVKELETQVGGKLFKNIK

PF00036 // ENSGT00390000013629_0_Domain_1 (228, 256)

MVTKAFKLIDVNK
TGLIQEGDLRRILDIFCMKMKDE-EYKK--------------------------------
-------FAKHYNIDKDAAVNYNAFMKDL-STNTALNLRYYLENQ---EDSLG-NQQTKY
SKKEYLPS-SVSSEDIWKNYSLDEIKNIFCQEFSKSYEHVEKALSAGDPTKGGFISLNYL
KIVLDTFVYRLPRRVFIQLMRXXXLRTTSRINWKHFLTLLKESQ----WLEANNAFPLAK
RNX-XX---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXKPDGCLTTEELRHILN
CMVIK-ISDS

PF00036 // ENSGT00390000013629_0_Domain_4 (551, 581)

EFEELLRTLDPSGTGMISVSTFVGL-LE-QDPKMRK--MS-YP-DTKEPP
PMAWDSVEEIIHDTIARNRHALREMLQSYDPGATGLISRNNFKKAMLIYCPFLTAEHLI-
-KLYSKFQDVASGRILYKKLLAYIGINNLSSSPAP-I--RKDPLEKRQ---------MPL
SEXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXSKEPCQQIGKHDFR
KVLEDNGMPMNNDQYALLTAKIGYKA-EGMSYLDLATRFAD-----NKISGPEVTSF-HA
PPPSKT--NLDSFFITAEECLKLFPR---RLKEYFRDPYS

PF00036 // ENSGT00390000013629_0_Domain_6 (881, 905)

AFFKIDTDRDGIINMHDLNR
LLRQLLINLKDEEFERFLHLLGLRLSMTLNFREFQGLFEKTPFRA-DDAPQRLIRPKQKV
ADSDLACEQAHQYLATKARNRWSDLSKNFLETDNEGNGILRRRDIKNALYGFDIPLTPRE
FEKLWTRXXXXXXXXXXXXXXXXXXXXXXXXXXSAELHRPYM----EDYFNFMGHFTKPQ
QLQEEMKELQQHT-------DKAVLIXXXXXXXXXXXXXXXXXXXXXEGSYISVCKILKV
LQEWGCPLKEEELTNLLK----SWGIGCHN-NTVNYLDFLRMLEN-K-PAKPQT-AEKE-
---ESVPVDFSMLNPDDMLKNVREVVATSSLALATACFALDKEDTGFLKASDFGQVLKDF
CYKLSDNQYHYFLRKLRLHLTPYINWKYFLQNFNSFLEENAAEWA---EKMPKGPPPPS-
SKEVAFHEILARLHKAVTA----HYHAIAQELENFDTMKTNTVSRDEFRAICTRH

PF08976 // ENSGT00390000013629_0_Domain_12 (1376, 1525)

VQVLT
D-------EQFDRLWNEMPVNAKGQLKCQDFLSSFSSEKVGTPQA-------SMDST---
HVQRGSSIREAS-SQRRSAM-SSRDLKA--------RPSHPCTPS----------TA-TS
LGIQPLQNCEPIESKLRKKIQGCW

ENSGT00390000013629_0_Linker_12_14 (1525, 1526)

R

PF00036 // ENSGT00390000013629_0_Domain_14 (1526, 1554)

ELLKDCKERDTDKQGEITAADFLALVEK

ENSGT00390000013629_0_Linker_14_16 (1554, 1637)

FSLDISK
EECQQLLVKYDLRNNGKFCYCDFIQSCVLLLKSKETSLMQRMKIQNANKMTETGPETCSF
YSALLRIQPQIVHCWR

PF00036 // ENSGT00390000013629_0_Domain_16 (1637, 1665)

PMRRTFKSYDEAGSGFLSVGDFRKVLRQYSINLSEEEFFHILEY
YDKTLSSRISYNDFLRAFLQ----------------------------------------
---------------

----------------------------------MHRMSILPDWHSLYSRT-QKLTCSRP
HSSPCKE-HLKTSCQD-----LCRPSSS--ATTTLSPDTTYFDTDVERILS

PF08976 // ENSGT00390000013629_0_Domain_0 (112, 182)

QKISNKKDE
MRKVFQVLDPTHRQTVTKGELKRVITAFLLPLTREQFQDLLAQIPLTSSGNVPYLEFLSR
F

ENSGT00390000013629_0_Linker_0_1 (182, 229)

G-GIDLNIN---VIKRGN--GNEIDYSRTIKEFEAQLIEKIFRNMKT

PF13202 // ENSGT00390000013629_0_Domain_1 (229, 253)

LEKVFHLIDVNN
TGVVQSQELRRVLEIFCLKMKDE-EYEM--------------------------------
-------FLKEYNISGTTAVDYNAFLKNL-SVSNDSNFRHLLSSS---EISRE-NQQAKT
GRRERPLN-SVSSEDVWKNYSLDDVEKTFCQELSKSYEKIEKALSAGDPSKGGYVSLNYL
KVVLDTFVYVLPRRIFIQLMKRFGLKTTTKVNWKQFLTAFYERQ----GLGVSKAIPLKK
RSR-YI---QNQC-TNHNIQ---------SYICAHT------------------LK-PIV
CITTHIMLESKLCCLK--------------------HV-HLPYVRK--MSPST-DTKAPL
PVAWDSVEEMVLDAITKNLQTFYGMLQSYDLGDTGTIARNNFKKVMRIFCPYLSNEHFV-
-KLSSKFQDTASGRIQYKKLLLSIGISVPPPTSPFSV--LKDQL-SEQNEDPG-PQT---
----QPVTD-------KTMTKEEVIDRLKQCIQQQDPVFKKQFLSISKQPDAKIGLEDFR
KVLEESGMPMNDSQYDMLISKIGYKK-EGMSYQDFTSGFED-----TKLSGLETVPQ-QS
RTASKT--NLDDRFTSAEECLRLFPK---KLKELFRDPYSAFFKVDTDMDGIINMHDLHR
LLQQLQLYMKDSEFERFLSLLGLRLSITLNFREFQNLCEKKPWKS-DEAPQRLLRYKQKV
ADSELACEQAHQYLVIKAKTRWADLSKNFIETDNEGNGILRRRDIKNALYGFDIPLTPRE
FEKLWQNYDIEGRGYITY----QEFLQRLGIRYSSKVHRPYK----EDYFNFLGHFTKPK
QIQEEIQELQQMTER------------EKLMDHYEEISKALNMLEKSKPGSAALCKVQKV
LQDCGCPLKEEELITLLK----SLGISVHN-NSINPLDLLRALET-SKTSKAQP-KEK--
EEGTPTPINFSMLNPEEVVKNMQVVVDSSQSALLKAFSALDKEDTGFVKAMDFGDVLKSF
CLKLTDNQYHYFLRKLRIHLTPHIHWKYFLENFSSFMEEAADEWA---EKMPKVPTPTS-
PKE

PF08976 // ENSGT00390000013629_0_Domain_11 (1324, 1444)

MANRDILSRVHKAVAS----HYHTIVQEFENFDTTKSNTVSRDEFRSICTRHVQILT
D-------EQFDRLWSEMPVNAKGRLKYQDFLSKFSTERLPSPPMDAGD---SGDST---
MAQRGSSAPEVS-QGTRSTL-CSPSQDPRA--G-LKSQSHPCTPV---------------
-GTPPLQNCEPIESKLRKQIQGCWRELLKECKEKDSDKQGSVTAAEFLALVEKFKLDISK
EESQQLIVKYDLKNNGKFAYCDFIQSCVLLLKAKETSLMRRMRIQNADKMKEAGVETQSF
YSALLRIQPKIVHCWRPM

PF13499 // ENSGT00390000013629_0_Domain_17 (1639, 1698)

RRTFKAYDENGTGLLSVADFRKVLRQYSINLSEEEFFHVLEY
YDKSLSSKISYNDFLRAFLQ----------------------------------------
---------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------

PF08976 // ENSGT00390000013629_0_Domain_11 (1398, 1441)

MPVNAKGRLRYLDFLSRFSSERAATPPA-------AGDLA---
EAQRGSSVPEVS-EGARSAISS-PAQDLRA--G-LRSQSHPCTPA----------HSAA-
-GTPPLQNCEPIESKLRRQIQGCWKELLRECKERDVNKQGEITAAEFLALVEKFNLDISK
EERQQLLIKYDLKNKGKFAYCDFIQSCVLLLKAKETSLLQRMKIQNAHKMKEVGAETSSF
YSALLRIQPKIVHCWRPM

PF13499 // ENSGT00390000013629_0_Domain_17 (1639, 1698)

RRTFKSYDEAGTGLLSVADFRKVLRQYSINLSEEEFFHILEY
YDKTLSSKVSYNDFLRAFLQ----------------------------------------
---------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------MNCCHTLRELEIQVGEKVFKNIKTVL

PF13202 // ENSGT00390000013629_0_Domain_1 (231, 253)

KAFKLIDVNK
TGLVQPQELRRVLETFCLKLRDE-EYEK--------------------------------
-------FSKHYNIHNDTAVDYNVFLKNL-SINNDLNLRYCIGNQ---AVSLE-NQQAKN
SKKERLLS-SASSEDTWRNYSLDEIERNFCLELSKSYEKIEKALSAGDPCKGGYVSFNYL
KIVLDTFIYQIPRRIFIQLMKRFGLKATTKINWKKFLTSFHEPR----GLEITSKGPLTK
RNS-IN---SRNESHKENIITKLFRHTEDRFTSLKKALLII-NTKP

PF13833 // ENSGT00390000013629_0_Domain_4 (527, 580)

NGPITREEFRHILN
CVAVK-LSDSEFKELMQTLDPGNTGVVNISVFIDL-VE-KNSRMRK--ASPCT-DTKTPF
LLAWDSVEEIVHDTITRNLHAFYNMLRAYDLGDTGLIGRNNFKKILHVFCPFLTNAHFI-
-KLCSKIQDIGSGRILYKKLLAHMGIDGPPTVSPVHV--PKDQLLSEHLRKDE-QQQPDL
SERTKPTENK--TTQIKKMTTEEVIEKFKNCIQQQDPEFKKRFLDFSKEPNGKINMRDFK
KVLEDTGMPMDDEQYALLTTKIGFEK-EGMSYLDFAAGFED-----PPVRAPETAPP-QP
PTPSKS--YVNSHFITAEECLKLFPR---RLKESFRDPYSAFFKIDTDRDGIINMHDLHK
LLGHLLFNLRDDEFERFLGLLGLRLSVTLNFREFRNLCEKRSLKT-DEAPQRLIRPKQKV
ADSELACEQAHQYLVTKAKNRWSDLSKNFLETDNEGNGILRRRDIKNALYGFDIPLTPRE
FEKLWASYDTEGKGHITY----QEFLQKLGVNYSPAVHRPCA----EDYFNFMGHFTKPQ
QLQEEMKELQQST-------EKAVAARDKLVDCYQDISKAFTKIDKSKTNYISICKMQKV
LEECGCSLTEGELTNLLN----SWGVSRHD-NSINYLDFLRAVEN-SKSTGAQP-KEKE-
---ESMPINFATLNPQEVVRKIQEVVESSQLALSTAFSALDKEDTGFVKSTEFGQVLKDF
CHKLTDNQYHYFLRKLRIHLTPYINWKYFLQNFSCFLEETAEEWA---EKMPKGPPPTS-
PKA

PF08976 // ENSGT00390000013629_0_Domain_11 (1324, 1444)

MASRDILARLHKAVTS----HYHAITQEFENFDTMKTNTISREEFRAVCNRNVQILT
D-------EQFDRLWNEMPVNAKGRLKYPDFLSRFSSERAATPTA-------TGDSA---
AAQRGSSVPDVS-EGIRSAL-SLPNQELRP--G-SKSQSHPCTAT----------STTAI
PGTPPLQNCDPIESRLRKRIQGCWRQLLKECKEKDVARQGDISASEFLALVEKFNLDISK
EECQQLIIKYDLKNNGKFAYCDFIQSCVLLLKAKESSLMQRMKIQNAHKMKDSGAETSSF
YSALLRIQPKIVHCWRPMRRTFKSYDEAG

PF13833 // ENSGT00390000013629_0_Domain_17 (1650, 1698)

TGLLSVADFRTVLRQYSINLSEEEFFHILEY
YDKTLSSNISYNDFLRAFLQ----------------------------------------
---------------

--------MKRNNVKLNVAKVNSTRSSSTKARDLLHKMSILPDWHTLYPST-QKMTYSRP
HSSPCRT-HSRTAFQD-----VCRPSSS--ATAIANPILSSL--DVERILSQRISCKRDE
IKKVFQVLDPTHSQAVTKGDLKRVITAFLLPLTREQFQDLLAQLPLTSSGNVPYLEFLSR
FG-GIDLNIN---VIRRGN--GNELDHNRTLKELETQL---IFRNMRT

PF13202 // ENSGT00390000013629_0_Domain_1 (229, 252)

IKKAFQLIDVNN
TGMMQSQELRRILETFCLKMRDE-EYKM--------------------------------
-------LLKQYSLDGSATVDYNTFLKNL-SVSNDTNFRYLLSNP---ELSRE-SQQAKN
ARRERLFN-SVSSEDVWKNYSLDDLEKTFCQELSKCYEKIEKALSAGDPSKGGYVSLNYL
KVVLDTFVYRLPRRIFIQLMKRFGLKTTTKVNWKQFLTTFYERQ----GLDVIKAAPLKK
RSS-TD---SRNQSRKENIVKKLFKYSEERYTALKKALLII-NTTPNGHISWEELRHILN
CVVAK-LSDSEFNELKQTFDPECTGSLKVSCLLDA-LD-DSPKVRK--MSPST-DTKAPV
PVAWDSVEEMLRDAITRNLQTFYGMLLSYDLGDTGTIARNNFKKVIRVFCPYLSNEHFI-
----NKFQDAASGRILYKKLLLTIGVNVPPTTSPPSV--PKDQP-NEQLQKEE-HIPPEL
PERTQPTRDK--IIEAKMMTKEEVIDRLKLCIQQQDPVFKKQFLSISKEPDTKIGLEGFR
KVLEEIGLPMNDSQFAQLTAKIGYKK-EGMSYQDFTSGFED-----TKLSGLETASL-QP
RTTSKT--KVDDHFISAEECLRLFPK---KQKELFSDPYSAFF

PF13202 // ENSGT00390000013629_0_Domain_6 (884, 901)

KIDTDRDGIINMHDLHR
LLQQLQLNMKDSEFERFLCLLGLRLSVTLNFREFQNLCENRPWKA-DEAPQRQIRYKQKV
ADSELACEQAHQYLIVKAKTRWADLSKNFIETDNDGNGILRRRDIKNALYGFDIPLTPRE
FEKLWQSYDTEGRGYITY----QEFLQRLGIRYSAKVHRPYK----EDYFNFLGHFTKPK
QVQEEIQELQQMTER------------EKLLGHYEEISKALNVLDKSKT-PAPLCKVQKV
LQECGCPLKEEELISLLK----SLGISVHN-SCIHPLDLLRALEI-HRTSKAQP-KEKD-
---EGTPVNFSKLNPEEVVKNMQAIVDSSQPALVKAFSALDKEDTGFVKAMEFGDVLKSF
CHKLTDNQYHYLLRKLRLHLTPSIHWKYFLENFSSFLEETADEWA---ENMPKVPPPTL-
SK

PF08976 // ENSGT00390000013629_0_Domain_11 (1323, 1444)

ESANRDILARMHKAVAS----HYHTIVQEFENFDTTKNNTVSRDEFRSICTRHVQILT
D-------EQFDRLWSEMPVNAKGRLKYQDFLSRFGTERAPSPPMAAGD---SGDST---
VAQRGSSAPEVS-QGSRSTL-CSPSRDSRS----AKSRSHPCTPV---------------
-GTPLLQNCEPIESKLRKQIQGCWRELLKECKEKDIDKQGSVTATEFLALVEKFKLDISK
EESQQLVVKYDLKGNGKFAYCDFIQSCVLLLKAKETSLMRRMRIQNADKMKEAGVETPSF
YSALLRIQPKIVHCWRPM

PF13499 // ENSGT00390000013629_0_Domain_17 (1639, 1698)

RRTFKAYDENGTGLLSVADFRKVLRQYSINLSEEEFFHVLEY
YDKSLSSKISYNDFLRAFLQ----------------------------------------
---------------

-------------------------------RDLMHKMDITPHWDTSCSPA-RELTHLRP
RSSPCRV-YSRTCFQN-----MFRPSST--ATAIANPILSSL--DIKRILFKKMTDKGD

PF00036 // ENSGT00390000013629_0_Domain_0 (120, 148)

E
VKKAFQLLDTGQNLTVSKNELRRVIGTFLLPLTRNQFQDVLAQIPLTSSGTVPYLEFLSR
FG-GMDLNVN---VIKRES--GNEMNQSRTLKELEIQLGDKVFRNIK

PF00036 // ENSGT00390000013629_0_Domain_1 (228, 256)

TVIKAFKLVDVNG
TGLVQPHELRRVLETFCLKMTDD-EYDK--------------------------------
-------FSRHYNIDKN-KVNYNVFLKSL-SVNNDMNLRHFMGNQ--VEVSWK-NQQAKN
SSKEYLPI-SDLSEDIWKNCSIDEIEKTFCQELLKSFEKVEKGLSAGDTCNSGYISLNYL
KVVLDAFVYRLPRRIFLQLMKRFGLKTTAKINWKQFLTSFYHPP----WLSFSGSVPMAR
RNSNIN---SRNQPNKENTITKLSRHAEDRFTSLKKALLLF-NNKSDGNVTGKELQNTLK
NNGVK-ISDSEFKELMQALDPGGTGLVNVPTFLDL-LEEENLKVRK--RSPCT-GTKTPL
PQAWDSVEEIVHGGITRNLPAFYNVLRSYDLGDTGFISRINFKKIMRTFCPFLTGEHLIK
SRLCSKFQDTASGRILYKKLLASIGINGLPTGSPNLV--PTHQLSTEHVQKEE-QQWPDL
PERVKPTEDK--TPVTKNLTKEEVVEKLKNCIQQHDPAFRKRFLDFSKEPHRKINEHDFR
KVLEAHGMPMDDDQYTLLTAKLGFRK-EGMSYLDFATGFED-----TEMSRPESTRT-QT
PVLTKS--YVNSHFITAEECLKLFPG---RLKESFRNPYS

PF00036 // ENSGT00390000013629_0_Domain_6 (881, 905)

AFFKMDTDRDGIISTQDLHR
LLLHLLFNLKDQEFERFLELLGLKLSITLNFREFRNLCEKGSYRS-DDPPQRLIRPKQKV
TDSELACEQAHQYLVTKATNRWPDLSKNFIETDREGNGILRRRDIKNALYGFDIPLTPR

PF00036 // ENSGT00390000013629_0_Domain_8 (1020, 1047)

E
FEKLWTRYDTEGRGHITY----QEFLQKLGINYSPAMHRPYA----EDYFNFMGHFTKPQ
QVQEEIKELQQNTER---------AIRDKLKDRFQEISKALTDLDKSKTGRVPLSKLQKA
LGECGCSLKEAELTELLN----RLETALHD-NSVNYLDFLKAVDG-SRPARPST-IEKE-
---ESKPINFAALRPEEMLKKVQEVVDSSHQ

PF00036 // ENSGT00390000013629_0_Domain_10 (1232, 1260)

ALWKTFSELDKEDTGFVKATEFGQVLKDF
CYKLSDNQYHYFLRKLRLHLTPYINWKYFLQNFNCFLEE---------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------

----------------------------------VCSMAIVPDWHTLYPHT-RKFTHLRP
HSSPCRV-YSRNGFQN-----MFRPSST---TAVANPMLSSL--DVKRIIFQKITDKGD

PF00036 // ENSGT00390000013629_0_Domain_0 (120, 141)

E
LKKAFHLLDTSNNMTVSKNELXXXXXXXXXXXXXXXXXXXXXXIPLTSSGAVPYLEFLSR
FG-GIDLNIN---VIKRGG--EDETNCCRTLKELEVHVGEKIFKNIK

PF00036 // ENSGT00390000013629_0_Domain_1 (228, 256)

TVIKAFKLIDINK
TGLVQPRELRRVLETFCLKMKDD-EYKQ--------------------------------
-------FAKHYNIDKDTAVNYNVFLKNL-STNNDLNLKYYIRSQ--XXXXXX-XXXXXX
XXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXFSKSYEKVEKALSAGDPSKGGV-FLNYL
KIVLDTYVYR-PRRIFIQLMKRFGLKTTTKVNWKQFLTSLYEPQ----WLEASNKIPLTK
RIS-IN---SRNQSRKENVITKLLRHE-DHYVSLKKALLIINAXXXXXXXXXXXXXXXXX
XXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XX--XXXXXX--XXXXX-XXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-
-XLCSKFQDVASGRILYKKLLACIGINGPPTASPVLV--PKDQLFNEHFQKEE-QQQPDP
SERTKPAGSK--SAVTENMTKDEVTAKLKACVQQQDPAFRKRFLDFSKEPSGKVTVQDFK
KVLEDNGMPMADDQYALLTAKLGYKK-EGMSYLDFATGFEX-----XXXXXPKVTPS-RT
PLSKGS----SDSYLITAECLKQFLG---RMKESFRNPYS

PF00036 // ENSGT00390000013629_0_Domain_6 (881, 905)

AFFKIDTDRDGIVSMRDLRR
LLLHLLLNLKDEEFERFLGLLSLRLSATLNFREFRNLCEKRPLRR-DDAPQRLIRPKQKV
ADSELACEQAHQHLVTKAKTRWSDLSKNFIETDSEGNGILRRRDIKNALYGFDIPLTPRE
FEKLWMXXXXXXXXXXXX----XXXXXXXXXXXXXXXXXXXX----XXXXXX---XXXXX
XXXXXXXXXXXXXXX----XXXXXXXXDKLKEHYQDVSKALTKQDESRNGYIALCQMQKL
LQECGCSLKEEELTDLLN----SWGISCHD-NSINYLDFLRAVEN-SKPTKPQP-QEKE-
---QGMSINFAALSPEEVLKNIQEVVASSSP

PF00036 // ENSGT00390000013629_0_Domain_10 (1232, 1260)

ALSTGFSALDKEDTGFVTASDFGQVLKE

ENSGT00390000013629_0_Linker_10_11 (1260, 1347)

F
CYKLTDNQYHYFLRKLRIHLTPYINWKYFLENFNSYLEETAAEWA---EKMPKGPPPRS-
PKEIAYQEILARLRKAVAS----HYH

PF00036 // ENSGT00390000013629_0_Domain_11 (1347, 1375)

TITQEFENFDTTKSDTASRDEFRAICTRHVQVLT
D-------EQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---XXXXX---
XXXXXXXXXXXX-XXXXXXX-XXXXXXXXX--X-XXXXXXXXXXX----------XX---
-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXDFIQSCVLLLRAKETPLMQRMKIQNAHKM----------
------------------------------------------------------------
------------------------------------------------------------
---------------

--------MKRNGTRLNFAKANSTKSGSTRARDLMNKMSIIPEWHSLYSNT-RKLPCSRP
HSSPCKM-Q-RTIFQD-----LCRPSSS--TTAIANPVLSYL--DIERILAQKISSRRDD
IKKVFQILDRNHNQMVTKGDLKRVITAFLIPLTKDQFQDLLAQIPISSLGNVPYLEFLSR
FGGGIDININ---GIKRVN--ENEVDNRRTVKEV--QLTEKIFRNMRS

PF13202 // ENSGT00390000013629_0_Domain_1 (229, 253)

IRKVFQVMDVNN
TGLVQPQELRRVLETFCLRMQDG-DYEK--------------------------------
-------FLEQYNIDKTTAVDYNAFLKNL-SVKNDASFKYLLSNA--AELSRE-TQQGKN
GK--RLLD-TGSSEDVWKNYSLDDLEKTFCQEFSKSYEKIEKALSAGDPSKGGYISLNYL
KVVLDTFIYRLPRRIFIQLIRRFGLKTSTKINWKQFLTAIYERQ----KLEVSKTLPLKK
RSS-TE---ARNRSRKENIIKKLFKYSEDRYTALKKTLLII-SSTPSGHITWEELRHILN
CMVAK-LNDSEFSELKQTFDPEGTGAVRVNSLLDV-LD-DSTKVRK--MSPST-DTKTPL
PVAWDSVEELVLDSITRNLQAFYSMLQSYDLRDTGTIGKNNFRKVMRVFCPYLSNEHLV-
-RFSSKFQEAGSGRILYKKFLLSIGVGIPPPTPPLSS--PKVQL-SDQFQIEE-PGQQ--
DERTQPSGEK--TSEINNMTKEEVIDGLKHRIQQKDPVFRKQFLSISKEPDVKINQEEFR
KVLERSGMPMNDCQYAMLASKLGFKNEEGMSYQDFTMGFED-----CMLSGLETVPL-QS
RTASRT--NMDEHFISAEECLRIFPK---KLKESFR

PF13833 // ENSGT00390000013629_0_Domain_6 (877, 903)

DVYSAFFRIDLDRDGIISMHDFHR
LLQYLQLNMVDLEFERFLSLLGLRLSVTLNFREFQNLCEKRPWKS-DEAPQRLIRCKQKV
ADSELACEQAHQYLIMKAKTRWADLSKNFIETDNEGNGILRRRDIKNSLYGFDIPLTPRE
FEKLWQNYDTEGRGYITY----QEFLHRLGIRYSPKVHRPYK----EDYFNFLGHFTKPK
QVQEEIQELQQISER------------EKLMNHYEEISKAFNAMEKSK--PVALCRVQKV
LQECGCPLKEEELISLLK----SLDVSVHN-NHIDPVEFLRALEI-SWASKARP-KEK--
EESSPPPISFSKVTPDEVIKTMQEVVESSQPALVEAFSALDKEDTGFVKAMEFGDVLRSV
CQKLTDNQYHYFLRRLRLHLTPNIHWKYFLENFSTFQDETADDWA---ENMPKAPPPMS-
PK

PF08976 // ENSGT00390000013629_0_Domain_11 (1323, 1444)

ETAHRDIVARVQKAVAS----HYHTIVQEFENFDTLKSNTVSRDEFRSICTRHIQILT
D-------EQFDRLWSELPVNAKGRLKYQDFLSKLSIERVPSPPMAAGD---SGEST---
MAQRGSSAPEFS-QGTRSNL-YSPPRDSRV--G-LKSRSHPCTPV---------------
-GTPPLQNCEPIESRLRKQIQGCWRELLRECKEKDTDKQGTISAAEFLALVEKFKLDISR
EESQQLIVKYDLKNNGKFAYCDFIQSCVLLLKAKETSLMRRMRIQNADKMKEAGMETPSF
YSALLRIQPKIVHCWRPM

PF13499 // ENSGT00390000013629_0_Domain_17 (1639, 1698)

RRSFKTYDKNGTGLLSVADFRKVLRQYSINLSEEEFFHVLEY
YDKSLSSKISYNDFLRAFLQ----------------------------------------
---------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------

PF08976 // ENSGT00390000013629_0_Domain_11 (1398, 1442)

MPVNAKGRLKYLDFLSMFSSERGAAPPA-------SGSST---
KAQKGCSVPEVS-ERSRSAASSTPAPDLKA--G-LKTQSHPPTPA----------SASP-
ADTLTLQNCEPIESKLRRRIQGCWREFLKECKEKDVTKQGEITTAEFLALVEKFSLDISK
EESQRLAVKYDVKNSGKFAYCDFIQSCVLLLKAKETSLMQRMKIQNANKMKEAGAETSSF
YSALLRIQPQIVHCWRPM

PF13499 // ENSGT00390000013629_0_Domain_17 (1639, 1698)

RRTFKAYDEGGTGLLSVADFRKVLRQHSINLSEEEFFHILEY
YDKTLSSKISYNDFLRAFLQ----------------------------------------
---------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-M----------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------------I
TDAELACDQAHYYLVIKARTRWHDLARNVQEFDSERNGTIQR-EHEKSLVQIGIAITPEE
FKKLWARYDNEAMSYHTE----QEFLQKLGMGYSPC-IKYPILFLIF--SNFWHLCLPLG
-MDSHLNHL------------QYAKERDKFRNYFQ

PF00036 // ENSGT00390000013629_0_Domain_9 (1116, 1133)

DFKKAFHKMDKNNDGYVTACDPQRF
LQEFNYHPDHDQFSSLLN----SLAISIHD-SKLSYFDFLRAIDD-GRASKYQ-QRQKQ-
---ATPPASFAALSLEQTLIKIKEIVASSCDLLYKAFSLVDKGDTRVIKTLEFQQVPDRF
CFKLSHKQFRNLLKNLNLLLTLILHSKNFIQNFISYSSRTLSTSH-FNLPKNKLPPHLS-
PEDTCCEGILLCIEKTLLP----RYFTYLGDFKDIDSSKDNTISKEVFWNICNQH

PF08976 // ENSGT00390000013629_0_Domain_12 (1376, 1525)

FQHLT
E-------EQFERTSDKIPLCPQGELKYQEFSKKFSSEQVTMSSTTPSATSPETSTKPVT
------CASSQP---EHPKTSSSLVGQESVSMVVTSASSHPQ---------------TTT
ECSAPVPNWEEIENKIRKNIQCSWRDILKLCQEKDVSKIGEIPVSDFPDIAEKFHLDLSK
EEISQITTKYDIKKNGKFAYYDFFQSCILLLKPQKSTLLQRVIIPKPQKPMSPGPQSMLF
YSTMLRIQPQILHCWR

PF00036 // ENSGT00390000013629_0_Domain_16 (1637, 1665)

PMKRTFKSYDESRTGLLNVADFRQVLHEYKINLSEEELFNILEY
YDKTLSSKISYNDFLRAFLQ----------------------------------------
---------------

----------------------------------MCKMAIIPDWLRSHPHM-RKFTHSRP
HSSPCRV-YSRNGSPD-----MFRSSS---TTAVANPTLSSL--DVKRILFQKITDRGDE
LQKAFQLLDTGQNLTVSKSELRRIITDFLMPLTREQFQDVLAQIPLSTSGTVPYLAFLSR
FG-GIDLYIN---GIKREG--GNEMNCCRTLRELEIQVGEKVFKNIKTVLKAFKLIDVDK
TGLVQPQELRRVLETFCLKLRDE-EYEK--------------------------------
-------FLKHYNIHNDTAVDYNVFLKNL-SINNDLNLRYCVGNQ--VEVSLE-NQQAKN
SKKERLLS-SASSEDTWRNYSLDEIERNFCLELSKSYEKIEKALSAGDPCKGGYVSFNYL
KIVLDTFIYQIPRRIFIQLMKRFGLKATTKINWKKFLTLFHEPR----GLEITSKGPLTK
RNS-IN---SRNESHKENIITKLFRHTEDRFTSLKKALLII-NTKPNGPITREEFRHILD
CVAVK-LSDSEFKELMQTLDPGNTGVVNISVFIDL-VE-KNSRMRK--ASPCT-DTKTPF
LLAWDSVEEIVHDTITRNLHAFYNMLLAYDLGDTGLIGRNNFKKILHVFCPFLTNAHFI-
-KLCSKIQDIGSGRILYKKLLAHMGMDGPPTVSPVHV--PKDQLLSGHLRKDE-QQQPDL
SERTKPTENK--TTQIKKMTTEEVIEKFKNCIQQQNPEFKKRFLDFSKEPNGKINVHDFK
KVLEDTGMPMDDEQYALLTTKIGFEK-EGMSYRDFAAGFED-----PPMRGPETTPP-QP
PTPSKS--YVNSHFITAEECLKLFPR---RLKESFRDPYSAFFKIDTDRDGVINMHDLHR
LLVHLLFNLKDDEFEHFLGLLGLRLSVTLNFREFRNLCEKRSLKT-DEAPQRLIRPKQKV
ADSELACEQAHQYLVTKAKNRWSDLSKNFLETDNEGNGILRRRDIKNALYGFDIPLTPRE
FEKLWASYDTEGKGHITY----QEFLQKLGVNYSPAVHRPCA----EDYFNFMGHFTKPQ
QLQEEMKELQQST-------EKAVAARDKLVDCYQDISKAFTKINKSKTNYISICKMQKV
LEECGCSLTEGELTNLLNR--TSWGVSRHD-NSINYLDFLRAVEN-SKSTGAQP-KEKE-
---ESMPINFATLNPQEVVRKIQEVVESSQLALSTAFSALDKEDTGFVKSTEFGQVLKDF
CHKLTDNQYHYLLRKLRIHLTPYINWKYFLQNFSCFLEETAEEWA---EKMPKGPPPTS-
PKAMASRDILARLHKAVTS----HYHAITQEFENFDTMKTNTISREEFRAVCNRN

PF08976 // ENSGT00390000013629_0_Domain_12 (1376, 1525)

VQILT
D-------EQFDRLWNEMPVNAKGRLKYPDFLSRFSSERAATPTA-------TGDSA---
ASQRGSSVPNIS-EGIRSAL-SLPNQELRP--G-SKSQSHPCTPA----------STTPI
PGTPPLQNCDPIESRLRKRIQGCWRQLLKECKEKDVARQGDISASEFLALVEKFNLDISK
EECQQLIIKYDLKNNGKFAYCDFIQSCVLLLKAKESSLMQRMKIQNAHKMKDAGAETSSF
YSALLRIQPKIVHCWRPMRRTFKSYDEAGTGLLSVADFRTVLRQYSINLSEEEFFHILEY
YDKTLSSKISYNDFLRAFLQ----------------------------------------
---------------

--------MKRNGTRLNFAKANSTKSGSTRARDLMNKMSIIPEWHSLYPNT-RKLPCSRP
HSSPCKV-Q-RTIFQD-----LCRPSSS--TTVIANPVLSYL--DI

PF08976 // ENSGT00390000013629_0_Domain_0 (107, 182)

ERILSQKISSRRDE
IKKVFQILDRNHSQTVTKGDLKRVITAFLIPLTKDQFQDLLAQIPISSLGNVPYLEFLSR
F

ENSGT00390000013629_0_Linker_0_1 (182, 229)

GGGIDININ---GIKRVN--ENEVDNRRTLKEV--QLTEKIFRNMRN

PF13202 // ENSGT00390000013629_0_Domain_1 (229, 253)

IRKVFQVMDVNN
TGLVQPQELRRVLETFCLKMQDG-DYEK--------------------------------
-------FLEQYNIDNTTAVDYNAFLKNL-SVKNDASFKYLLSNA--AELSRE-TQQGKN
GK--RPLD-TTSSEDVWKNYSLDDLEKTFCQEFSKSYEKIEKALSAGDPSKGGYISLNYL
KVVLDTFIYRLPRRIFIQLIRRFGLKTSTKINWKQFLTAIYERQ----KLEVSKTTPLKK
RSS-TE---ARNRSRKENIIKKLFKYSEDRYTALKKTLLLI-SSTPSGHITWEELRHILN
CMVAK-LNDSEFSELKQTFDPEGTGAVRVNSLLDV-LD-DSTKVRK--MSPST-DTKTPL
PVAWDSVEELVLDSITRNLHAFYSMLQSYDLGDTGTIGKNNFRKVMRVFCPYLSNEHLV-
-RFSSKFQEASSGRILYKKFLLSIGVGIPPPTPPLSS--PKVQL-SDQFRTEE-PGQQ--
DERTQSSGDK--TTESNNMTKEEVIDSLKHRIQQKDPIFRKQFLSISKEPDVKINQEEFR
KVLERSGMPMNDCQYAMLASKLGFKNEEGMSYQDFTMGFED-----CMLSGLETVPL-QS
RTASRT--NMDEHFISAEECLRIFPK---KLKESFRDVYSAFF

PF13202 // ENSGT00390000013629_0_Domain_6 (884, 901)

RIDLDRDGIISMQDLHR
LLQYLQLNMVDLEFERFLSLLGLRLSVTLNFREFQNLCEKRPWKS-DEAPQRLIRCKQKV
ADSELACEQAHQYLIMKAKTRWADLSKNFIETDNEGNGILRRRDIKNSLYGFDIPLTPRE
FEKLWQNYDTEGRGYITY----QEFLHRLGIRYSPKVHRPYK----EDYFNFLGHFTKPK
QVQEEIQELQQITER------------EKLMNHYEEISKAFNAMEKSK--PVALCRVQKV
LQECGCPLKEEELISLLK----SLDVSVHN-NHIDPVEFLRALEI-SWASKARP-KEK--
EESSPPPVSFSKLTPDEVIKTMQEVVEASQPALVKAFSALDKEDTGFVKAMEFGDVLRSV
CQKLTDNQYHYFLRRLRLHLTPNIHWKYFLENFSTFQEETADEWA---ENMPKAPPPTS-
PK

PF08976 // ENSGT00390000013629_0_Domain_11 (1323, 1444)

EAAHRDILARVQKAVAS----HYHTIVQEFENFDTLKSNTVSRDEFRSICTRHIQILT
D-------EQFDRLWSELPVNAKGRLKYQDFLSKLSIERVPSPPMAAGD---SGEST---
VAQRGSSAPEFS-QGTRSNL-YSPPRDSRV--G-LKSRSHPCTPV---------------
-GTPPLQNCEPIESRLRKQIQGCWRELLRECKEKDTDKQGTISAAEFLALVEKFKLDISR
EESQQLIVKYDLKNNGKFAYCDFIQSCVLLLKAKETSLMRRMRIQNADKMKEAGMETPSF
YSALLRIQPKIVHCWRPM

PF13499 // ENSGT00390000013629_0_Domain_17 (1639, 1698)

RRSFKTYDENGTGLLSVADFRKVLRQYSINLSEEEFFHVLEY
YDKSLSSKISYNDFLRAFLQ----------------------------------------
---------------

----------------------------------MCKMAIIPDWLRSHPHT-RKFTHSRP
HSSPCRV-YSRNGSPN-----KFRSSS---TTAVANPTLSSL--DVKRILFQKITD

PF08976 // ENSGT00390000013629_0_Domain_0 (117, 182)

RGDE
LQKAFQLLDTGQNLTVSKSELRRIITDFLMPLTREQFQDVLAQIPLSTSGTVPYLAFLSR
FG-GIDLYIN---GIKRGG--GNEMNCCRTLRELEIQVGEKVFKNIKTVMKAFELIDVNK
TGLVRPQELRRVLETFCMKLRDE-EYEK--------------------------------
-------FSKHYNIHKDTAVDYNVFLKNL-SINNDLNLRYCMGNQ---EVSLE-NQQAKN
SKKERLLG-SASSEDIWRNYSLDEIERNFCLQLSKSYEKVEKALSAGDPCKGGYVSFNYL
KIVLDTFVYQIPRRIFIQLMKRFGLKATTKINWKQFLTSFHEPQ----GLQVSSKGPLTK
RNS-IN---SRNESHKENIITKLFRHTEDHSASLKKALLII-NTK

PF13833 // ENSGT00390000013629_0_Domain_4 (526, 578)

PDGPITREEFRYILN
CMAVK-LSDSEFKELMQMLDPGDTGVVNTSMFIDL-IE-ENCRMRK--TSPCT-DAKTPF
LLAWDSVEEIVHDTITRNLQAFYNMLRSYDLGDTGRIGRNNFKKIMHVFCPFLTNAHFI-
-KLCSKIQDIGSGRILYKKLLACIGIDGPPTVSPVLV--PKDQLLSEHLQKDE-QQQPDL
SERTKLTEDK--TTLTKKMTTEEVIEKFKKCIQQQDPAFKKRFLDFSKEPNGKINVHDFK
KVLEDTGMPMDDDQYALLTTKIGFEK-EGMSYLDFAAGFED-----PPMRGPETTPP-QP
PTPSKS--YVNSHFITAEECLKLFPR---RLKESFRDPYSAFFKTDADRDGIINMHDLHR
LLLHLLLNLKDDEFERFLGLLGLRLSVTLNFREFQNLCEKRPWRT-DEAPQRLIRPKQKV
ADSELACEQAHQYLVTKAKNRWSDLSKNFLETDNEGNGILRRRDIKNALYGFDIPLTPRE
FEKLWARYDTEGKGHITY----QEFLQKLGINYSPAVHRPCA----EDYFNFMGHFTKPQ
QLQEEMKELQQST-------EKAVAARDKLMDRHQDISKAFTKTDQSKTNYISICKMQEV
LEECGCSLTEGELTHLLN----SWGVSRHD-NAINYLDFLRAVEN-SKSTGAQP-KEKE-
---ESMPINFATLNPQEAVRKIQEVVESSQLALSTAFSALDKEDTGFVKATEFGQVLKDF
CYKLTDNQYHYFLRKLRIHLTPYINWKYFLQNFSCFLEETADEWA---EKMPKGPPPTS-
PK

PF08976 // ENSGT00390000013629_0_Domain_11 (1323, 1444)

ATADRDILARLHKAVTS----HYHAITQEFENFDTMKTNTISREEFRAICNRRVQILT
D-------EQFDRLWNEMPVNAKGRLKYPDFLSRFSSETAATPMA-------TGDSA---
VAQRGSSVPDVS-EGTRSAL-SLPTQELRP--G-SKSQSHPCTPA----------STTVI
PGTPPLQNCDPIESRLRKRIQGCWRQLLKECKEKDVARQGDINASDFLALVEKFNLDISK
EECQQLIIKYDLKSNGKFAYCDFIQSCVLLLKAKESSLMHRMKIQNAHKMKEAGAETPSF
YSALLRIQPKIVHCWRPMRRTFKSYDEAG

PF13833 // ENSGT00390000013629_0_Domain_17 (1650, 1698)

TGLLSVADFRTVLRQYSINLSEEEFFHILEY
YDKTLSSKISYNDFLRAFLQ----------------------------------------
---------------

--------MK-----------QGSTKGNTKARNLMNKMMNIPGGHALYPHT-RKFTCSRP
HSSPCRV-YSKNGFQN-----IFRPSSS--PSAAANPILSFL--DVKRILFQ

PF08976 // ENSGT00390000013629_0_Domain_0 (113, 182)

KITDKKDE
LKKAFQLLDASQNLTVTRSELRRIITTFLLPLTKEQFQDVLAQIPLTSSGNVPYLEFLSR
FG-GVDLNIN---VIKRGG--GNEVNCCRTLKELEIHIGEKIFRNAKTIIKAFQLVDVNN
IGLVQPQELMRVLETFCLKMKEE-EYRK--------------------------------
-------FSKHYNIDKDTAVDYNMLLKNL-SINNDLHFRYFMSNQ---EVSPE-NQQAKT
FKREHLLN-SAPSKESWNNCSLDDVEKVFCQEFSKSVDKIEKALSAGDPSRGGYVSLNYL
KIVLDTFVYRLPRKTFLQLMKR--------------------------------------
------------------------------------------------------------
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---------------

--------MKRNST-----KGNSTKSGSTKARNLMNKMMNTPDGRALYPRT-RKFTRSRP
HSSPCRV-YSKDGFRN-----TFRPSSS--PSAAANPILSFL--DVKQILFQKI

PF08976 // ENSGT00390000013629_0_Domain_0 (115, 182)

TDRRDE
LKKAFQLLDVGQNLAVTRRELRRIVTTFLLPLTKEQFQDVLAQIPLTSSGNVPYLEFLSR
F

ENSGT00390000013629_0_Linker_0_1 (182, 230)

G-GIDLNIN---AIKRGG--RDEVNCCRTLKELEIQVGQKVFRNLKTI

PF13202 // ENSGT00390000013629_0_Domain_1 (230, 253)

IKAFQLVDVNN
TGLVQPQELMRVLETFCLKMTEE-EYRKAPRRAVGLATPEPTLPFPPWHHAFHWVVPGHS
GVTTSLGFSKHYNIDKDAAVDYNMFLKNL-SISNDLHLRYFMWNQ---EVSPE-NQQAKT
LKREQSLD-SAPFEESWNNYSLDDVERVFCQEFSKSVEKIEKALSAGDPSRGGYVSLNYL
KVVLDTFVYRLPRRTFLQLMKRFGFKTTTRINWKQFLTSFYELQ----GLENSNIVPPLK
RDR--------NQSCGENVITKLLRHAEDSYGFLKKGLLMNSTSE

PF13833 // ENSGT00390000013629_0_Domain_4 (526, 578)

PDRQITGEELRQILS
STVMK-LKDSEFKELMSTLDPGGTGAVKVSSFIDL-LE-ASPKMRQ-M-PPRT-GAKTSL
LPAWDSVEETVHRAIAKNLRAFYNMLQSYDLGDSGFVARNNFKRVMRIFCPFLTNEHLI-
-KLCCKFQDTTSEKILYKKFLSCIRINGPPTVSPLLV--PKDQP-NECFQKGE-EQQPVL
SERTKPTSDR--TATTKNMSKEEVIEKLKSCVKRQDPAFRNCFLDVSKDLHGKISMRDFK
KVLEDCGMPMDQVHFALLATKIGCKK-EGMSYLDFVTGLED-----TKTSGLAATPP-QT
PVSSKI--HLNGHFITAEECLKLFPK---RLKASFRDPYSAFFKIDTDRDGIVNMRDLHR
LLQRLLFNLKDEEFERFLGLLGLRLSVTLNFREFQNLCEKRSPQM-DEAPQRLIRPKQKV
ADSELACEQAHQYLVIKAKNRWADLSKNFIETDTEGNGILRPRDIKNALYGFDVPLTPRE
FEKLWQSYDTEGRGCITY----QEFLQKLGINYSPAVHRPYA----EDDFNPLGRFTKPQ
QVQEEIQELQQSIER-------AVPARDQLMGHCQDISKALSALDKSQSGSVPLCKMQQV
LQECGCPLKEEELTGLLH----SLGIICHD-NAINYLDFLRALEN-SKTTRPQP-KEKE-
---ESVPISFSTLSPEEVVKNIQEVVSSSHPALLQTFSALDKEDTGFIKATDFGQVLKDL
CYNLTDSQYHYFLRKLRIHLTPYIHWKYFLENFGCFLEETADEWA---GKMPRVPPPAS-
PQE

PF08976 // ENSGT00390000013629_0_Domain_11 (1324, 1444)

VANRDLLARLHKAVTS----HYHAIAQEFENFDTNKTNTASRDEFRAICTRHVQILT
D-------KQFDRLWSKMPVNDKGRLKYQEFLSRFGPERAATPPA-------TGDSA---
RAQRGSSVPEIS-EGTRSSAVSPSTHDPRA--G-LKSRSHPCTPA---------------
-GTPSLQNYEPIESRLRKQVQGCWRELLQECKEKDVGRLGTITAPDFLELVHKFRLDVSV
GERQQLLAKYDLRNNGTFAYCDFIQSCVLLLGARETSLTQRMKIQNAHKMKEAGAETSSF
YAALLRIQPKILHCWRPMRRMFKAYDKGGTGFLSTDNFRKVLRQFSINLSEEEFFHLLEY
YDKSLSSKVAYNDFLRAFLQ----------------------------------------
---------------

----------------------------------MCKMAIIPDGQISYPHT-RKFTSLRP
HSSPCRV-DLRNSFQN-----VFRPSSS--TTALANPILSFL--DVKRILFQKITNKGDE
LKKAFQLLDTSQSMTVSKSDLRRVITTFLLPLTREQFQDVLAQIPLTSSGAVPYNEFLSR
FG-GIDLNIS---VIKRGD--GNETNCCRTLGELEIQVGEKIFKNIKTVMKALKLIDVNK
TGLVQARELRRVLETFCLKMKDD-EYKK--------------------------------
-------FAKHYNIDTDTAVDYNAFLKNL-SVNNALNLRYHMGDQ---EVSRE-NQQIKS
SRRERLPS-SISSEEVWRDYSLDEIERAFCQELSKSYEKVEKALSAGDPSKAGHVSLNYL
KVVLDTFVYQLPRRIFIQLMKRFGLKTTAKVNWKQFLTSLYESP----WLEVNNIVPPTK
RNS-IN---SRNKSCKENIITKLFRHE-DRYALLKKALLLT-NAQPDGQITGEELRRILN
CMVVK-ISDSEFKELMQILDPGGTGWVNVNTLGEL-LE-EKAATGR--TSSCA-DTKAPL
LLAWDSVEEIVHDAITRNLQAFYNMLRSYDLGDTGLIGRNNFKKILRIFCPFLTTEHLI-
-KLCSKFHDMASGRILYKKLLTCLGIKGPPAISPVLV--PKDQLSREQPQKEE-EQQPDL
SERAKPAESE--ITATRKMAKEEVIEKLKSCIRRQDPVFRRRFLDVSKELHRKINARDFK
KVLEDHGMPMDDDQYALLTAKIGFKK-EGMSYLDFATGFEV-----PPMQEREVTPS-QT
PVPAKS--NLDS-FVTAEECLRQFPQ---RLKESFRGPYSAFFEMDTDRDGIISMLNLHQ
LLQRLLLNLRDEEFERFLGLLGLRLSTTLNFREFQNLCEKRPLRT-DDVPQRLIRPKQKV
ADSELACEQAHQYLVTKAKTRWSDLSKNFIETDNEGNGILRRRDIKNALYGFDIPLTPRE
FEKLWMSYDTEGRGHITY----QEFLQKLGISYSADVHQPYA----EDYFNFMGHFTKPQ
QVQEEIKELQQSTEK-------AVPAREKLKDHYQDISKAVTKLDKSKNGYVSLSSMQKV
LQECGCPLREEELTDLLS----SWGISWHD-NSINYLDFLKAVEN-SKPTRPQP-EEKE-
---ESTPINFATLNPEDILKSIQEVVASSGPALSMAFSALDKEDTGFVKASDFGQVLKDF
CYKLTDSQYHYFLRKLRIHLTPHVNWKYFLQNFGDFLEETAAEWA---EKMPKGPPPRS-
SKEMANQEILARLHKAVTS----HYHTIAQEFENFDTMKTHTASRDEFRSICTRH

PF08976 // ENSGT00390000013629_0_Domain_12 (1376, 1525)

VQVLT
D-------EQFDRLWNEMPVNAKGRLKYLDFLSRFSSERAATPPD-------TDDSA---
KAQRGSSVPTVS-AE------SSPTGDPKA--G-SKPRSHPCTPA----------SAILE
PSAQPLQNCEPIETKLRKGIQSCWREFLRECKERDVNKQGEITAPEFLALVEKFNLDVNR
EECQQLLVKYDLKNSGRFAYCDFVQSCVLLLKAQETSVMRRMKIQNAHKMKEAGAETSSF
YAALLRIQPKIVHCWRPMRRTFKAYDEGSTGLLSVADFRQVLRQYSVNLSEEEFFHILEY
YDKTLTSKISYNDFLRAFLQ----------------------------------------
---------------

---------------------------------------------------------MVV
HSE-VVL-VSQLSVRL-----INSCLSFI-ATAMANPILSSL--DVKRIL

PF08976 // ENSGT00390000013629_0_Domain_0 (111, 188)

FQSITNKGDD
LKKAFHLLDTGNDRTVSKNELRRVIADFLLPLTREQFQDILAQIPLTRAGAVPYLEFLSR
FG-GTDLNVN---AVKRGG--ENAMNHCRTLRDLEAQVAEKIFKNIHTVAKAFKLLDVNK
TGLVQARELRRVLETSVRGLLDERFYFR--------------------------------
-------FAKHYNVDKDTAVDYNVFLKNL-GTNNDLNLKYDVGSQ---EVSWE-EQRAKN
PSRECLPS-SLSPEDIRGNYSLDDLERVFCQELSRSHERVEKALSAGDPSRGGYVSLNYL
KIVLDTFVCRLPRRIFIQLMKR--------------------------------------
------------------------------------------------------------
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---------------

----------------------------------MYKMANVPDWHTSYPHT-RKFMNLRP
HSSPCRV-YSRSSFQN-----MFRPSSS--ATAIANPILSFL--DVKRILFQKITDKGD

PF00036 // ENSGT00390000013629_0_Domain_0 (120, 148)

E
LKKAFQLLDTGHNMTVSKNELRSIITTFLMPLTREQFQDILAQVPLTSSGAIPYLEFLSR
FG-GLDLNIN---VIKRGG--ENEMSCSRTVKELETQIGEKIFKNVK

PF00036 // ENSGT00390000013629_0_Domain_1 (228, 256)

TVIKAFKLIDVNK
TGLIQPCELRKVLETFCLKMKDD-EYRK--------------------------------
-------FAKHYNIDKDTAVDYNVFLKNL-SVNNDLNLRYSVGNQ---EISWN-SQPVKN
PKGECLHG-SVSSDDVWKNCSLDEIERTFCQELPKSYEKVEKALSAGDPCKSGYVSLNYL
KIVLDTFVYRLPRRIFIQLMKRLGLKTTTKINWKQFLTSLYESQ----WLEVNNTVPLTK
RNS-IS---SRNQSRKENIITKLSRHE-DHYA

PF00036 // ENSGT00390000013629_0_Domain_3 (513, 542)

SLKKALLIA-DTNSDGQITGEELLRILN
CMVVK-ISDSEFKELMQTLDPGDTGWVNVYTFIEL-LE-ENPKIRK--LSSRT-DTTAPV
LPAWDSVEEIVQDSITRNLQAFYKMLQSYDLGDTGLIGRNNFKKIMRIFCPFLTIEHLL-
-KLCSKFQDIASGRILYKKLLARMGISGPPTISPVLV--PKDQLLREGFQKEK-QQPLDV
SERAKPTEDG--GTLTKNMTKDEVIEKLKNRIQQRDPAFRKLFLDFSKELNGKINVRDFK
KVLEASGMPMDDDQYTLLTAKLGYKK-EGMSYLDFEAGFED-----AKMNGPEVTPL-QT
PVLSKN--NLDSYFITAEECLKQFPQ---RLKEAFRDPYS

PF00036 // ENSGT00390000013629_0_Domain_6 (881, 905)

AFFQIDTDRDGIINMHDLHR
LLLHLLFNLKDEEFERFLGLLGLRLSVTLNFREFRNLCEKRPFRT-DDAPQRLLRPKQKV
TDSELAYEQAHQYLVTKAKTRWSDLSKNFIETDNEGNGILRRRDIKNALYGFDIPLTPR

PF00036 // ENSGT00390000013629_0_Domain_8 (1020, 1047)

E
FEKLWMSYDTEGRGHITY----QEFLQKLGINYSADIHRPYA----EDYFNFMGHFTKPQ
QMQEEVKQLEQSMDR-------AVPVKEKLKDHYQDISRALTKLDKSRNGCISVGRMQKV
LQECGSSLKEEELTDLLNR--TSWGISWHD-NSFNYLDFLKAVES-SKPTRPQP-KEKE-
---ENVPINFATLDPEEVVKNVQEVVAASDVALSMAFSALDKEDTGFVKASDLGQVLKDF
CYKLTDNQFHYFLRKLKIHLTPHINWKYFLQNFSSFFEETAAEWA---EKMPKGPPPTS-
SKGTANQELLARLHKAVGS----HYHAIAQEFENFDTMKTNTASRDEFRAICSRH

PF08976 // ENSGT00390000013629_0_Domain_12 (1376, 1525)

VQILT
D-------EQFDRLWSEMPVNAKGRLRYPDFLSTFSSEKAATPPT-------ADSSV---
KAQRGSSVSEVV-DGSGSAA-PSPTHDLKA--A-LKPPSHPCTPA----------SAGSA
LGPLPLQNCEPIESKLRKKIQGCW

ENSGT00390000013629_0_Linker_12_14 (1525, 1526)

R

PF00036 // ENSGT00390000013629_0_Domain_14 (1526, 1554)

EFLKECKEKDVNKQGEITTAEFLALVEK

ENSGT00390000013629_0_Linker_14_16 (1554, 1637)

FSLDLSK
EESQQLVGKYDLKSAGRFAYCDFIQSCVLLLRAKETSLMQRMKIQNAHKMKESGAETSSF
YSALLRIQPKIVHCWR

PF00036 // ENSGT00390000013629_0_Domain_16 (1637, 1665)

PMRRTFKAYDEGGTGLLSVADFRKVLRQYSINLSEEEFFHMLEH
YDKTLSSQISYNDFLRAFLQ----------------------------------------
---------------