Query Results 

------------------------------------------------------------
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--------------------------------------------MSDAEENPLVETEEYG
EIEMEEGEDGGGG---EEDPYYK-ELENMQEESKEDNTLAWRESQGE---------EEEE
-GEEGEEGEKE---KGMEEE-KGEEEKEGEEEK--RVEEEGEEEE---EEEEVG----KE
-------E-EALREEVEEEASGAQEET----------------------AV--K-PQEAT
KS-----R--------------NNLDRLTPTDSQSI---------------------LLG
TLPK---TS------SSGKSKQS---LQSELSETSEPPRDLSSQLDFLDVDP----TTYR
EQRISSSE----RQ---------PS------------------------GEPGEQ-TDQT
PQDELEQ-ERRDSEPERGDLEPETRESRKDKRVSYISEKSEKAFQPKG---RTPKDSLVS
TATEDILFQK---DDSANVYPLTMTWTFGWNSSLPVYYIRDENHRVLLYASAHTAVIYNV
FK

PF00400 // ENSGT00390000013370_0_Domain_0 (663, 704)

NNQHHLQGHPNVISCLCVS--EDRRWVATADKGPDCLIIIWDSFTGIPVHT--IFDSC
PEGNGIRAMAITRDAKYLATISDA-----EIQ-RVCIWRWTLAVETPACTLDLPKEYGFQ
--NYLTFNPTNNKELVSNSKTQAIYYMWYE--------------------DGDILAH--S
APLLTEKTFNKLVGKFSQSVFHLNLTQILSATMEGKLVVWDICRPTSSA-----------
---------SISSGFPHIKPCKLVHLQKEGITVLTTVDSYIVTGDIRGNIKFYDRTLSIV
NWYSHFKLSCIRSLSFSKTPATPPTEDTNYP------PDCTLKGDLFVVRNFIIGTSDAS
VYHLTADGTKLEKLFVEPKDAIRAISCHPYQPLIAIGSFCGMIKVWDYEKKKYLFSRVFE
KGLGVQSLTYNPEG-------------------------------------ALLGAGFTE
GTVYILDAMSLESEIPEPFKYSRTSVTHISFSHDSQYMATADV---SFTVAVYMVRVRNG
RRVWEYLARLRSHRKSIRSVLFGVHLDSNEPRLLSLGRDRLLIEYNLLKSYKDHLEVLDI
HRTDQGSYPTCMVWYPPLIKEL-----FLLICNSGYKVKLFNSTTKMCRKT----LLGPV
------YGSPIEQ--------IQILPVKTATELQK-RYLVFINRDKVGLQILPVDGNPHK
TSALICHPSGVAGLTLSYDGRYAFTAGGLDRSVVQWEINLSALEAAVSLGGEDLTPFYGL
VAGGREGKFYRELEDYFYYSQLRSQGIDTMETRKVSEHICLSELPFVMRAIGFYPSEEKI
EDMFNEIRFSEYVDTGKLIDKINLPDFFKVYLNHRPPFGNTMTGIQQSFDILGFTNSKGE
KVIRREDFLKLLLTK----GEHMTEEEMSDCFATLFGLNPEGWKSEPAA-SSVKG--SEI
CFEKELPDEITAEIFTTEILGLTISQDSGQDPTFSNRTR--IRDAKS-------------
------------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------MSDA-----EETEEDG
ETEMEE----------DYNPNYK-DVENTQQESQEDDTLAWSGFPDE---------EEGE
-GEEEGEEEEE---GGEE----GEE-REGEEK---EKREEGEEEE---GEEEKG---EEE
-------E-REEGEEEE--REGEEDRE----------------------G----------
-------E--------------EREEREEEEGEESV---------------------TIT
SCQK---TH------TGSESKHS---LQSEGSETNL--RRLSSGHEFYDSDE----TSFE
EQQVSSPE----IQ---------PS------------------------GDLEEE-TTQM
PKDELGQ-EGRDLESEMEKKGQEKKV--------------SVFLDQKA---GITRQSMVS
TTTEDILFQK---DD-STLYPLTMTWWFGWNSSLPVYYLREENERVLLFVCAHTAVIYNV
SRNY

PF00400 // ENSGT00390000013370_0_Domain_0 (665, 704)

QYHLQGHPNVISCLCVS--EDRRWIATADKGPDCLIIIW

ENSGT00390000013370_0_Linker_0_1 (704, 1036)

DSFTGIPVHT--IFDSC
PEGNGIRAIAMTRDSKYLATISDA-----EVQ-KVCIWKWTLAVEVPACTLELPKEYGLQ
--NHLTFNPTNDKELVSNSRTQAIYYSWYE--------------------ERKILAH--S
APLLTEKTFNKLVGKFSQSVFHLNLTQILSATLEGKLVVWDIHRSPSSS-----------
---------SAFLGSSYIKPCKLVHLQKEAITVLTTVDSYIVTGDIKGNIKFYDHTLSIV
SWYSHLNSSPIRTLSFSKIPASPPTEKSNYP------PDCTLKGDFFVVRNLIFGTSDAA
VYHLTIDGTKLEKLF

PF00400 // ENSGT00390000013370_0_Domain_1 (1036, 1067)

VEPKDAICAISCHPYQSLIAIGSFCGMIKVWDYEKKKYLFSRVFE
KGLGVQSLTYNPEG-------------------------------------ALLGAGFTE
GTVYILDAMSLENDTPEPFRYSRT

PF00400 // ENSGT00390000013370_0_Domain_3 (1165, 1187)

SVTHISFSHDSQYMATADV---SFTVAIYMMVVKRG
KRVWEYLARLRSHRKSIQSLLFGVHLDSNEPRLLSLGRDRLLIEYNLRRSCKDHLEVLDI
HRTDQGDYPTCMVWYPPLAKEL-----FLLICNSGYKVKLFNSTTKMCRKT----LLGPA
------YGSPIEQ--------AQVLPARTTMELQK-RYLVFINRDKVGLQILPVDGNPHK
TSAIICHPNGVAGLALSYDGCYAFTAGGHDRSVVQWKINLSALEAAVSLGGDDLIPFYGL
VSGGREGKFYRELEDYFYYSQLRSQDIDTMETRKVSEHICLSELPFVMRAIGFYPSEEKI
DDMFNEIKFSEYVETGKLIDKINLPDFLKVYVNHRPPFGNTMSGVQESFNVLGYTNSKGK
KAIQREDFLKLLLTK----GEHMTEEEMSDCFATLFGLNPEGWKSEPAT-SSFKG--AEI
CLEEELPDEITAEIFTTEILGLAISEDS--------------------------------
------------------------------------------------------------

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------------------------------------------------------------
SPPS------------------SATDYLR---DSS----SLELSYSYE--------NQLE
--QPNSPLRR------------QSSD-------ELGDR--------SDLMPLEKPG----
------Q-EKRGLGPER-----------------------GEKQKERSSTKRMPKSSLVS
TANEDALF-HK--DDSGTVYPLNMTWSFGWNSSLPVFYIRDNTQRVLLYICAHTVVIYDV
F

PF00400 // ENSGT00390000013370_0_Domain_0 (662, 694)

SNSQHHLQGHPNVISCVCIS--EDRRWVATAD

ENSGT00390000013370_0_Linker_0_1 (694, 1029)

RGPECLIIIWDSFTGXXXXX--XXXXX
XX-XXXXXXXX-XXXXXXXXX-XXXXXXXX-X-X-XXXXXXXXXXXXXXXXXXXXXXXXX
--XXXXXXXXXXXXXXXXXXXXXXXXXXLEG--------------------RDTLIH--S
APLLTEKTFNKIVGKFSQSVFHLDLTQMLSATMEGKLVVWDI-HRPHASG----------
---------SITSAFPYIKPCKLVHLQREAITVLTTIDXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------XXXXXXXXXXXXXDFIIATSDAT
VYHLTADG

PF00400 // ENSGT00390000013370_0_Domain_1 (1029, 1067)

TKLEKLLVEPKDSICAIACHPYQPLLTIGSFCGMIKVWNYEKKKYLFSRVFE
KGLGVQSLTYNPEG-------------------------------------ALLGAGFTE
GTVYILDAMSLENEIPEPFKYSRTSVTHISFSHDSQYMATAXX---XXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXRVHLNCIEPRLLSL-GDCLLXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXX-----XXXXXXXXXXXXXXXXXXXXXXXX----XXXXX
------XXXXXXX--------XXXXXXXXXXXXXX-XXXXXXXXXXVGLQILPVDGNPHK
TAAIICHPSGVAGLALSYDGCYAFTAGGRDCSVVQWQINLSALDAAVSLGGEDLTPFYGL
VAGGKEGKFYRELEDYFYYSQLRSQGIDTMETRKVSEHICLEELPFVMRAIGFYPSEEQI
DNMFNEIRFSEYVDTGKLIDKINLPDFLKVYVNHRPPFGNTMSGIQQSFNILGFSNSKGK
KVIRREDLLRLLLTK----GEHMTEEEMSDCFATLFGLNPEGWKSEPAA-SSYKG--SKI
CYEDDLPE-ITAEILATEILGLTISQNSHKNGQ---------------------------
------------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------MSDAEEPPLEEAEENG
ESEMEE----------DNTPNFE-EAENIQRKSKEYDTLAWIDSQDE---------EEGE
-EMKRKEK----------------------------------------------------
-------K-KAGEAQEEEESSGVQEET----------------------TV--E-SQEIT
KS-----E--------------ISMEKLI-TGSQSA---------------------MSG
TFPE---TR------RGSESKHS---LQSEGSKTKELSRVQSSQLRILDLDE----ISSE
KQEVSSLE----RQ---------PS------------------------GELEEE-TVSM
PQDELGR-GGRHLEPEKGKEGGDE---------------KEKDVPSKA---GISKESLVS
TTSEDILFQK---EE-GTEYPLTMTWSFGWNSSLPVYYIREKNQRVLLYVCAHSAVIYNV
SR

PF00400 // ENSGT00390000013370_0_Domain_0 (663, 704)

NNQYHLQGHANVISCLCIS--EDRRWIATADKGPDCLIIIWDSFTGIPVHT--IFDSC
PEGNGIRAIAMTLDAKYLATISDA-----EIQ-VVCVWKWTLAVDTPACTLKLPGEYGFQ
--KYLIFNPANNKELVSNSKTQAIYYLWNE--------------------ERGTLTH--S
APLLTEKTFNKLVGRFTQSIFHLNLTQILSATKEGKLVVWDIHRSPSSS-----------
---------SASLGTPYIKPCKLVHLQKESITVLTTVDSYIVTGDIKGHIKFYDHTLAIV
NWYSHFKLSPIKTLSFSTTLPAPPTEKSNYP------PNCTLKGDLFIVRNLIIGTSDAT
VYHLTTDGTKLEKLFVEPKDAVCAISCHPYQPLIAVGSFCGMIKVWDYEKKKYIFSRVFE
KGLGIQSLTYNPEG-------------------------------------ALLGAGFTE
GTVYILDAMSLENESAEPFRYSRASVTHICFSHDSQYMATADV---SFTVAVYVVVVKSG
KRVWEYLARLRSHRKSIRSLLFGVYLDNNEPRLLSLGSDRLLIEYDLLKSHKDNLEVLDI
HRSGQGSYPTCMVWYPPLTKEL-----FLLICNSAYKVKLFNSTTKMCRKT----LLGPA
------YGSPIEQ--------AQVLPVKTTRELQK-RYLVFINRDKVGLQILPIDGNPHK
TAA

PF00400 // ENSGT00390000013370_0_Domain_4 (1384, 1417)

ITCHPNGVAGLALSYDGRYAFTAGGYDHSVVQWKINLSALEAAVSLGGEDLTPFYGL
VPGGREGKFYRELEDYFYYSQLRSQGIDTMQERKVSEHICLSEVPFVMRAIGFYPSEEKI
DDMFNEIKFSEYVDTGTLIDKISLPDFLKVYVNHRPPFGNNMSGIYKSFDILGYTNSKGK
KAIRREDFLKLLLTK----GEHMTEEELSDCFASLFGLAPEGWKSEPAT-SSFKG--AEI
CLEEELPDEITAEIFTTEILGLTISEDSKQYVH---------------------------
------------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------MSDPEGEPPE---EHG
EKEGE---------EQEYNQDDK-EVEDTGQESP-EDAWGRRGSQEGEGQGEGGEKQ--E
---EEEEENEE----------EGEEEEEE-------QDEEGEEEEEE-------------
---------QEQEQEEAEAEAGEA-QE----------------------EAAGV-RDIVT
A-------------------------------PQYN---------------------LLG
SFLE----------IL--GDTGSKQSTQSDGS-------------ENVDLAQ----VHPD
K-QMK------------------SS------------------------GELGTG-MEPE
QQDTLEQ-EGRDQGQKQGGARGERGSTRPRKGISYLDGDQDTQFQTRA---GYSRESLVS
RSTEDTLFQK---DEGAQVYPLALNWSFGWNSSLPVFYIRERNQRVLLYACGHTAVIYNV
AK

PF00400 // ENSGT00390000013370_0_Domain_0 (663, 704)

NTQHHLQGHPNVISCLCVS--EDRRWIATADKGPGCLIILWDSFTGIPVHT--IFDSC
PQGNGIRAIAISRDAKYLATISDA-----EVQ-EVSIWRWTLAVETPACTLKLPREYGSQ
--NYLTFNPANNKELVSNSKTQTIYYWWHE--------------------ERDTLVH--S
APLLTENTFNKLVGKFSQSIFHPNSSQILSATLEGKLVVWDIQRRPTPA-----------
---------PGSADGPSIKPCKLVHLQKEAVSVLTVADGYIVTGDVKGHIKFYDQTLSIA
HWYSHLQLSCIRTLSFSQSAASM-HQSANFP------PDCTLKGDLFVVRNFIIATSDAT
VYHLTTDGTRLEKLFVEPKDAVCAISCHPYQPLLAVGSVCGLIKVWDYQRKRYLFSRVFD
KGLGVQSLTYNPEG-------------------------------------ALLGAGFTE
GTVYILDAMSLQNETPEPFKYSRSSVTHVSFSHDSQYMATADL---SFTVAVYTVVVRGG
RRLWEYLARLRSHRQSIRSLLFGVYLDSNEPRLLSLGKDRLLIEYNLSRSHKDHLEVLDI
HRTDQGHHPTCMVWYPPLTKEL-----FLLVCNSGYKVKLFNSTTKMCRKT----LLGPA
------YGSPIEQ--------AQVLPVRTAPELQK-RYLVFINRDKVGLQILPVDGNPHK
TCAMVCHPNGVAGLALSYDGRFAFTAGGQDRSVVQWTITLSALDAAVSLGGEDLTPFYGL
VPGGREGRFYRELEDYFFYSQIRSQGIDTMETRKVSEHICLAEVPFVMRAIGFYPSEEKI
EDMFNEIRFSEYADTGKLIDRINLPDLLKVYVNHRPPFGNTLRGLRQSFAVLGTPNEQGE
SVVRRDALLQLLLTR----GEHMTEEEMTDCFATLSGLNPEGWKSEPAA-SACRG--SEI
SLEEELPDEITAEIFASEVLGLTISEDPGEDGP---------------------------
------------------------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----IKTIAITRDAKYLATISDG-----KDQ-KVCIWKWTLAVDTPACTLDLNKEYGFQ
DNNYLIFNPTNNKELVSNSKTRAIYYSWYE--------------------EKNTLAH--S
APLLTEKTFNKLVGKFSQSVFHLNLTQILSATMEGKLVVWDIHRPPPS------------
---------ATFLGFPYIKPCKLVHLQKEGITVLTTIDSYIVTGDIKGNIKFYDHTLSIV
NWYSHFKLSPIRTLSFSKTPPSPSTEKSNYP------PDCTLKGDLFIVRNFIISTSDAT
VYHLTADG

PF00400 // ENSGT00390000013370_0_Domain_1 (1029, 1067)

TKLEKLFVEPKDAICAVACHPYQPLLAIGSFCGMIKVWDYESKTYLFSRVFE
KGLGVQSLTYNPEG-------------------------------------AILGAGFTE
GTVYILNAMSLENEIAEPFRYSRSSVTHISFSHDSHYMATADV---NYTVALYWVVVRHG
QRVWEYLARLRSHRKSIRSLLFGVHLDSNEPRLLSLGRDRLLIEYNLLRTCKDHLEVLDI
HRTDQGCYPTCMVWYPPLQGTL-----PAHLQQRLQSEAL--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------MSDTEENPLEETEEYG
EIEMQEEDDEE-----EEYPNFE-GLENMQQELKEVNTLAWIESPEEEEEEEEGEEEGRE
FGEEAEAEDGEE--GEVEIREEEEEDRKGKEE--GEEEGEGEERVEEHEEEEAG-KGEEV
VEGLGKEAVKDQALEADEEASETQEES----------------------TV--E-PEEIT
TS-----M--------------ISLERFMQTDSQTV--------------------LSET
SLN------------SGSESKHS---LQSELLETFELPRSPGSQLEFLDLDV----TTSG
EPLISFPE----RQ---------PS------------------------GEL-----DQR
PQDELEEEEGRDLEPERGDLEQEKRERRKEKRVSCISEKSEKESQPKA---RITKASLVS
TATEDVLFQS---RESANTYPLTMTWSFGWNSTLPVYYIRE-NQRVLLYASGHTGVIYNV
LKNN

PF00400 // ENSGT00390000013370_0_Domain_0 (665, 704)

QHHLQGHPNIISCLCIS--EDRRWVATADKGPDCLIIIWDSFTGIPVHT--IFDSC
PEDNGIRAMAITRDAKYLATISDA-----EIQ-KVCIWKWTLAAETPACTLDLPKEYGFQ
--NYLIFNPTNNKELVSNSKTQAIYYTWVSRTVFICFKYMDKYLFIL-------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------MSDAEELPQEETEENG
ETEMEE----------DNNPNYK-EVENMQQESKEDDTLEEGEEREG---------K---
---------KE---EEV-------------------------EEE---EKAVIE----ET
-------E-EKAGEAKEEEASGIQEET----------------------TV--E-PQEII
KS-----T--------------ISMEKLS-TSSQST---------------------MSG
TFAK---TR------RGSESKHS---LQSEGSKTKELPRVRSSQLGFLDLDE----ISSE
KQQVSSLQ----RQ---------LL------------------------GELEKK-TIRM
PQDELGQ-EGRDLEPEKGKRGLDE---------------KEKDVQSKA---GISKESLVS
TTSEDILFQK---EE-GAVYPLTMTWSFGWNSSLPVYYIREKNQRVLLYVCAHSAVIYNV
SR

PF00400 // ENSGT00390000013370_0_Domain_0 (663, 704)

NNQYHLQGHPNVISCLCIS--EDRRWIATADKGPDCLIIIWDSFTGIPVHT--IFDSC
PEGNGIRAIAMTLDAKYLATISDA-----EIQVKVCIWKWTLAVDTPACTLQLPKEYGFQ
--KYLTFNPTNNKELVSNSKTQAIYYSWVSRNVLICFKCGDYFFCTHQNEERETLAH--S
APILTEKTFNKLVGKFSQSVFHLNLTQILSATMEGKLVVWDIYRSPSSS-----------
---------SASLGAPYIKPCKLVHLQKESITVLTTVDSYIVTGDIKGNIKFYDHTLAIV
NWYSHLKLSSIRTLSFSVTLAAPPTEKSNYP------PDCTLRGDFFIIRNLIIGTSDAT
VYHLTTDGTKLEKLFVEPKDAICAISCHPYQPLIAVGSVCGMIKVWDYEKKKYIFSRVFE
KGLGVQSLTYNPEG-------------------------------------ALLGAGFTE
GTVYILDAMSLENESPEPFRYSRTSVTHISFSHDSQYMATADV---SFTVAVYMVVVKSG
KRVWEYLARLRSHRKSIRSLLFGVHLDNNEPRLLSLGRDRLLIEYNLLKSHKDHLEVLDI
HRTDQGSYPTCMVWYPPLTKEL-----FLLICNSAYKVKLFNSTTKMCRKT----LLGPA
------YGSPIEQ--------AQVLPVKTTSELQK-RYLVFINRDKVGLQILPVDGNPHK
TAAI

PF00400 // ENSGT00390000013370_0_Domain_4 (1385, 1417)

ICHPNGVAGLALSYDGRYAFTAGGHDRSVVQWKINLSALEAAVSLGGEDLTPFYGL
VPGGREGKFYRELEDYFYYSQLRSQGIDTMQTRKVSEHICLSELPFVMRAIGFYPSEEKI
DDMFNEIKFSEYVDTGKLIDKINLPDFLKVYLNHRPPFGNNMSGIHKSFDVLGYTNSKGK
KAIRREDFLKLLLTK----GEHMTEEELSDCFATLFGLNPEGWKSEPAT-SSFKG--SEI
CLEEELPEEITAEIFTTEILGLTISEDSEQYGQ---------------------------
------------------------------------------------------------

MSDTEENPLEESRESGEMEEEKEEKKEEEEEEEE-GEKEKEEE--------------EEE
EKGKEEEKEEEKEEGKEEEKKEEE--------EEKGKKEEEEE----EEEEGKGKEE---
EKEEEKEEEEKEEEKEKEEEEEEEGKGKEEE---------EEGKEEEEEEKE----EEEK
EEEKEEEEEEE-EEKEEYNPSF--EEDALQQSL-TEGSLSW----EESQEDGEGLE---E
WVEKEEQREGEEVRGEEESEVRGREEEEGWEE-----EKSGEEEKSEESERSKERGGEEE
GQE--KEEAEHEGE---REE-GRE------------EEEKEKSVEREEEEEEED-----T
ETT-ETKAGRAKEEKKEKQNKTALVDNI-----------------------------V--
--I-----------SH--E-PPR---SSS---SLADSPEV-SQIYKDNSMKV----DDTE
EA--------------------------------------------------SQK-PEDI
LAQGKDE-AR------------------------LSLEERRKLFQSKG---LSAEESLVS
VSTEDTLFQ-K--EEDSKVYPLSMTWSFGWNSSLPVYYMRED-RRVILYTCAHTAIMYDV
VR

PF00400 // ENSGT00390000013370_0_Domain_0 (663, 704)

NTQYHLQGHPNIISCLCVS--EDRRWIATADEGPDCLIIIWDSFTGIPVHT--IFDSC
PEGNGMRSIAITRDSKFLATISDS-----ATQ-KVCIWKWTLAVETPACTLELPKEYGFQ
--DNLVFNPANNKELVSNSKTQAIYYCWFE--------------------DKGILAH--S
APVLTEKTFNKLVGKFSQSVFHLKLPQVLSATKEGKLVVWDIHYPSSTS-----------
--------SSAISAFPFIKPRKLVHLQKEAITVLMTIDSYIVTGDIKGNIKFYDHTLSVV
NWYSNFKLGAIRTLSFSKTIPSLPTEKSNLP------TDCTLRGDLFVVRNFIIGTFDAT
VYHMTVDGTKLEKLFVEPRDAVYAVSCHPYQPLIAVGSVCGMIKVWDFEKKVYLFSRTFE
KGLGVQCLTYNPEG-------------------------------------ALLGAGFTE
GTVYILDAMSLENESPEPFKYSKSSVSHCCFSHDSNYMATADV---NFTVAVYMVVVKNG
QRVWEYLARLRSHQNSIQSLLFGVHLDSNEPRLLSLGKDRFLIEYNLVKSCKDHLDVLDV
HRTDQGNYPTCMIWYPPLTKEL-----FLLICNSGYKVKLFNATTKMCRKT----LLGPA
------YGSPIEH--------AQVLPVKSTLELQK-RYLVFINKDKVGLQILPVDGNPHK
TCAIVCHPNGVAGMALSYDGRFAFTAGGQDRSVVQWKINLGALEAAVSLGGEDLTPFYGL
VSGGREGKFYRELEDYFYYSQIRSQGIDTMETRQVSEHICLSELPFVMRAIGFYPSEEKI
EDMFNEIKFSEYVETGKLIDKINLPDFLKVYLNHRPPFGNTMDGIQNSFNVLGYTNSEGK
KAIRREDFLNLLLTK----GEHMTEEEMIDCFSTLFGLTPEGWKSEPAA-TCING--PEI
CLQKELPEEITAEIFTTEILGLTLSDSSEQLIQ---------------------------
------------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------MSDAEGNPLEEA-EDG
ETEMKEEE----------HPDYS-EEEENVPQKSGDDLLPRRETQEEKEAEE-----EGE
-GN-------------LEEE-EGEG------N-LKEEEGGGSLK----------------
---------EEEGEGSLKEEEGSQEEI------------------------PGA-SQQIT
MA-----M--------------VSLEGLSSTDSESL--------------------MSEN
SLVS---SNRHSFKIIGRESEHS---LPTESLST------LSSP-SDYELAL----TSSE
EKLIISLQKKMARL---------SS------------------------GELA-------
------Q---------EKVSEPVKGEKRREKKVSYVDKGKEEELQPVAHTPAADKESLVS
TSSKDVLFQK---DDGAKVYPLTMTWKFGWNSSLPVYYIRDEEQRVLLYANAHTAVIYNA
H

PF00400 // ENSGT00390000013370_0_Domain_0 (662, 692)

KNTQHHLRGHPNVISCMCVS--EDRRWIAT

ENSGT00390000013370_0_Linker_0_1 (692, 1029)

ADKGPNCLLMIWDSFTGIPVHT--IFDSC
PDGEGIRAIAMTRDAKYLATISDA-----EIQ-KVCIWRWTLAAETPACTLDLPKEYGFQ
--NYLIFNPTNNKELVSNSKVRAIYYLWYE--------------------ERGILIH--S
APLLTEKTFNKHVGKFSQSIFHLNLTQVLSATLEGKLVVWDVYRPPLST-----------
---------S---TLPYIKPCKLVHLQKEGITVLTTVDSYIVTGDVKGNIKFYDRTLSIM
NWFSNFKLSSIRTLSFSKTPATPPTEKSNYP------SDCTLKGDIFVIRNFIIGTSDAI
VYHLKADE

PF00400 // ENSGT00390000013370_0_Domain_1 (1029, 1067)

TKLEKLLIEPKEAICAISCHPYQPLITIGSSCGMIKVWDYKKKKYLFSRVFE
KGLGIQSLTYNPEG-------------------------------------DLLGAGFTE
GTVYILDAMSLENGIPEPFNYSRTSVTHISFSHNSQYMATADA---NFTVAVYMVKVRHS
ERVWEYLARLRSHRQSIRSLLFGVHLDSNEPRLLSLGRDRLLIEYNLLGSYKNHLEVLDI
HQTDQGNYPTCMIWYPPLTKEL-----FLLISNSGYKVKLFNSTTKMCRKT----LLGPS
------LRVSHEQ--------VQVLPVKTAMELER-RYLVFINRDKVGLQILPIDGNPHK
TCAIVCHPNGVAGMALSHDGHYVFTAGGQDLSVVQWEVNLSALEAAVSLGGEDLIPFYGL
VSGGREGKFYRVLNGYSYFKSHTHTHTYYLETF-KNIHVGQGGVPAVFEARALMSSREKI
DDMFNEIKFSEYVDTGEVIDKISLPDFLKVYLNHRPPFGYTMSSIQKNFDILGYTNSEGK
KAIRREDFLRLLLTK-GCPGEHMTEEELSDCFATLLGLNPEGWKSEPAA-SSLKG--PEV
RWEEELPEEITAEIFVTDILGLTISPGFGQDAE---------------------------
------------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------MSDAGEHPLEETEEDG
ETEMEE----------DYN--YR-GMESMQQELKD-DILVWREPQQEGEQEE-----EGE
-------EEGEE--KEGVEE-EGEEGEEWEK--------------------ERG---EEE
-------GEEEGEEGKEEEAAGVQEET----------------------TV--K-LREIT
KS-----M--------------VNLERLTSTRSQSI--------------------MSGT
FL-------K-----TLSESKH---SIGSKHSETSELLRDWSSKLRFLDLDQ----TSSE
QQQIHFPE----TQ---------PS------------------------SEPTEK-IDQM
PQDELGQ-ERRDLEPGK-----------EEERLSSLSEEEEKEFQPKA---EIPESSLVS
-TSEDILFQK---DYSANVYPLTMTWSFGWNSSLPVYYIRDENQRVLLYVCAHTAVIYNV
FKNT

PF00400 // ENSGT00390000013370_0_Domain_0 (665, 704)

QHHLQGHLNVISCLCIS--EDRRWIATADKGPNCLIIIW

ENSGT00390000013370_0_Linker_0_1 (704, 1037)

DSFTGIPVHT--IFDSC
PEGNGIGSIAITRDAKYLATISDA-----EIQ-KVCIWRWTLAVETPACTLDLPKEYGFQ
--NYLTFNPTNNKELVSNSKTQAIYYVWYE--------------------ERDILAH--S
APRLTEKTFNKLVGKFSQTVFHLNLTQILSATMEGKLVVWDIHRPSSSA-----------
---------STSVGFPQIKPCKLVHLQKEGITVLTTVDSYIVTGDIRGNIKFYDHNLSIV
NWYSHFKLSSIRTLSFSKTPAAPPTEKSNYP------PDCTLKGDFFIVRNFIIGTSDAT
VYHLTTDGTKLEKLFV

PF00400 // ENSGT00390000013370_0_Domain_1 (1037, 1067)

EPKDAICAISCHPYQPLIAIGSFCGMIKVWDYEKKKYLFSRVFE
KGLGVQSLTYNPEG-------------------------------------VLLGAGFTE
GTVYILDAMSLENQIPEPFKYSRTNVTHISFSHDSQYMATADV---HFTVAVYKVIVKNG
HRVWEYLARLRSHRKSIRSLLFGVQLDSNEPRLLSLGKDRLLIEYNLLRSRKDNLEVLDI
HRTDQGNYPTCMVWYPPLTKEL-----FLLVCNSGYKVKLFNSITKMCRKT----LLGPV
------FGSPIEQ--------IQILPVKTTLELQK-RYMVFINRDKVGLQILPVDGNPHK
TSAIVCHPSGVAGMALSYDGCYAFTAGGQDRSVVQWEVNVSALEAAVSLGGEDLTPFYGL
VAGGREGKFYRELEDYFYYSQLRSQGIDTMETRKVSEHICLSELPFVMRAIGFYPSEEKI
EDMFNEIRFSEYVDTGKLIDKINLPDFFKVYLNHRPPFGNTMSGIQHSFDILGFTNSKGK
KVIRREDFLKLLLTK----GEHMTEEEMRDCFATLFGLNPEGWKSEPAA-SSVKG--SEI
CFEEELPDEITAEIFTTDILGLTISQDFRQDPT---------------------------
------------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------MSDAEEAPRESTGKNG
ETEKKEEE--------EPNPNYK-EVENPQEELQ-DDTLAWRESQEEE---------E--
--------EEE---------------EEE------------G-----EDKEIVM---EET
-------E-EKAGEAQEEEASGIQKET----------------------TV--E-PQEMK
KS-----M--------------TSLEIRI-TDSQSI---------------------TSG
IFPT---TQ------RGSESKPS---LQSEDSEAD--------ELEFLDLDQ----LSPE
EQQMSSPE----RQ---------PS------------------------GELEN--TDQR
PQDELER-ERRDLEPEKREEGQERS---------------MSSIQSIA---GISRESLVS
TTTEDILFQK---DKSAPVYPLTLTWSFGWNSSLPVYYIREEKQKVLLYVCAHTVIIYNV
FR

PF00400 // ENSGT00390000013370_0_Domain_0 (663, 704)

NHQYHLQGHANIISCVCIS--EDRRWVATADKGPDCLVIIWDSFTGIPVHT--IFDSC
PEGNGIRAMAMAHDAKYLATISDA-----EVQ-KVSIWKWTLAVETPACTLELPKEYGFQ
--NYLTFNPKNNKELVSNSKTQAIYYAW--------------------------------
-------TFNKLVGKFSQSIFHLNLTQILSATMEGKLVVWDIHRPPSST-----------
---------STFLSFPYIKPCKLVHLQKESITVLTTIDSYIVTGDIKGNIKFYDHTLSIV
NWYSHLQLSAIRTLSFSKTPATPPTEKSNYP------PDCTLKGELFVVRNFIIGTSDAT
VYHLTTDGTKLEKLFVEPKDAICAISCHPYQPLIAIGSICGMIKVWNYEKKRYLFSRVFE
KGLGVQSLTYNPEG-------------------------------------ALLGAGFTE
GTVYILDAMSLENESPEPFRYSRTSVTHISFSHDSQYMATADV---SFTVAVYMVVVRNG
RRVWEYLARLRSHRQSIRSLLFGVYLDSNEPRLLSLGTDRLLIEYDLLRSYKDHLEVLDI
HRTDQGCYPTCMVWYPPLTREL-----FLLICNSGYKVKLFNATTKMC------------
----------------------------------------------VGLQILPVDGNPHK
TTAI

PF00400 // ENSGT00390000013370_0_Domain_4 (1385, 1417)

VCHPNGVAGMALSYDGRYIFTAGGHDRSVVQWKINLSVLEAAVSLGGEDLTPFYGL
LSGGREGKFYRELEDYFYYSQLRSQGIDTMETRRVSEHICLSELPFVMRAIGFYPSEEKI
EDIFNEIKFGEYVDTGKLIDKINLPDFLRVYLNHRPPFGNTLSSIQKSFEVLGYTNSKGE
KAIRREDFLRLLITK----GEHMTEEEMLDCFASLFGLNPEGWKSEPAT-SSVKG--SEI
CLEEELPDEITAEIFATEILGLTISEDSGQDGQ---------------------------
------------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------MSDAEEAPREATGENG
ETEMKEEE--------EPNPNYK-EVENLQQESK-DNTLVWRESQEE---------ERKM
-GEEEGE-----------------KEEEGKE-----------------DKKIVM---EET
-------E-EVAGEAQEKEASGIQEET----------------------TV--E-PQEVT
ES-----M--------------SRLETEI-TDSQSI---------------------TSG
IFPK---TQ------RGSKSKPS---LQLEDTETDELLRGLSTQLEFLDLDQ----ISPE
EQQISSPE----RQ---------PS------------------------GELEEK-TDQM
LQDELER-ERRDLEPENREEGQESR---------------VSDIQSEA---GISRESLVS
STTEDILFER---DESAPVYPLTMTWSFGWNSSLPVYYIREEKQRVLLYVCAHTAIIYNV
FR

PF00400 // ENSGT00390000013370_0_Domain_0 (663, 704)

NNQHHLQGHANIISCLCVS--EDRRWIATADKGPDCLVIIWDSFTGIPVHT--IFDSC
PEGNGIRAMAMTHDAKYLATISDA-----EVQ-KVCIWKWTLAVETPACTLELPKEYGVQ
--NYLTFNPTNNKELVSNSKTQAIYYAWYE--------------------ERDTLAH--S
APLLTEKTFNKLVGKFSQSIFHLNLTQILSATMEGKLVVWDIHRPPSSA-----------
---------STFLGFPYIKPCKLVHLQKEGITVLTTIDSYIVTGDIKGNIKFYDHTLSIV
NWYSHLKLGAIRTLSFSKTPATPPTEKSNYP------PDCTLKGDLFVLRNFIIGTSDAA
VYHLTTDGTKLEKLFVEPKDAICAISCHPYQPLIAIGSICGMIKVWNYENKQYLFSRVFE
KGLGVQSLTYNPEG-------------------------------------ALLGAGFTE
GTVYILDAMSLENESPEPFKYSRTSVTHISFSHDSQYMATADR---SFTVAVYMLVVRSG
QRVWEYLARLRSHRKSIRSLLFGVYLDSNEPRLLSLGTDRLLIEYDLLRSYKDCLEVLDI
HRTDQGCYPTCMVWYPPLTREL-----FLLICNSGYKVKLFNATTKMCRKT----LMGPA
------YGSPIEQ--------TQVLPVRSTAELQK-RYLLFINRDKVGLQILPVDGNPHK
TSAIV

PF00400 // ENSGT00390000013370_0_Domain_4 (1386, 1417)

CHPNGVAGIAVSYDGRYAFTAGGHDRSVVQWKITLSVLEAAVSLGGEDLTPFYGL
LSGGREGKFYRELEDYFYYSQLRSQGIDTMETRKVSEYICLSELPFVMRAIGFYPSEEKI
DDIFNEIKFGEYVDTGKLIDKINLPDFLKVYLNHKPPFGNTMSGIHKSFEVLGYTNSKGK
KAIRREDFLRLLVTK----GEHMTEEEMLDCFASLFGLNPEGWKSEPAT-SSVKG--SEI
CLEEELPDEITAEIFATEILGLTISEYSGQDGQ---------------------------
------------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------MSDAEENPLEETEEYG
EIEMQEEDD--EE---EEYPNFE-GLENMQQELKEVNTLAWIEEEEE---------EDR-
-KGKEEGEEEG---E-------------------------GE-ER---VE----------
---------EHEEEEADEEASGAQEES----------------------TV--E-PEEIT
SS-----M--------------ISLERFMQTDSQTS---------------------PFY
FFFL---KN------SGSESKHS---LQSELLETFELPRSPGSQLEFLDLDV----TTSG
EPLISFPE----RQ---------PS------------------------SEL-----DQR
PQDELEEEEGRDLEPERGDLD-------------------EKESQPKA---RITKASLVS
TATEDVLFQS---RESANTYPLTMTWSFGWNSTLPVYYIRE-NERVLLYASGHTGVIYNV
LK

PF00400 // ENSGT00390000013370_0_Domain_0 (663, 704)

NNQHHLQGHPNIISCLCIS--EDRRWVATADKGPDCLIIIWDSFTGIPVHT--IFDSC
PEDNGIRAMAITRDAKYLATISDA-----EIQ-KVCIWKWTLAAETPACTLDLPKEYGFQ
--NYLIFNPTNNKELVSNSKTQAIYYMWYP--------------------EGGILAH--S
APVLTEKTFNKLVGKFSQSVFHLNLTQILSATMEGKLVVWDIYRPPPSA-----------
---------SSSMGFPHIKPCKLVHLQKEGITVLTTVDSYIVTGDIRGNIKFYDHTLSIV
NWYSHFKLSCIRSLSFSKTPAVPPAENTNYP------PDCTLKSDHFVVRNFIIGTSDAS
VYHLTVDGTKLEKLFVEPRDAICAISCHPYQPLIAIGSFCGIIKVWDYEQKKYLFSRVFE
KGLGVQSLTYNPEG-------------------------------------ALLGAGFTE
GTVYIFDAMSLESAISEPFRYSRSSVTHISFSHDSQYMATADV---SFTVAVYVVRVKHG
QRVWEYLARLRSHRKSIRSVLFGVHLDSNEPRLLSLGRDRLLIEYNLLKSYKDHLAVLDI
HRTDQGSYPTCMVWYPPLTKEL-----FLLICNSGYKVKLFNSATKMCRKT----LLGPV
------YGSPIEQ--------IQILPVKSTLELQK-RYMVFINRDKVGLQILPVDGNPHK
TSALICHPNGVASMALSYDGCYAFTAGGQDRSVVQWEINLSALEAAVSLGGEDLTPFYGL
VSGGREGKFYRELEDYFYYSQLRSQGIDTMETRKVSEHICLSELPFVMRAIGFYPSEGEI
EDMFNEIRFSEYVDTGKLIDKINLPDFFKVYLNHRPPFGNTMSGIQQSFDILGFTNSKGE
KAIQREDFLNLLQTK----GEHMTEEEMTDCFATLFGLNPEGWKSEPAA-SSVKG--SEI
CLEEELPDEITAEIFTTEILGLTVSQDSRQDPRITEAEQ--SF-----------------
------------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------MSDAEEAPREATGENG
ETEMKEEE--------EANPNYK-EVEDPQQESK-DDTLAWRESQEE---------ERKT
-GEEEGEEE-------------EKEEEEGKE-----------------DKKIVM---EET
-------E-EKAGEVQEKEASGIQEET----------------------TV--E-PQEVT
ES-----M--------------IRLETQI-TDSQSI---------------------TSG
IFPK---TQ------RGSKSKLS---LQLEDAETDELLRDLSTQIEFLDLDQ----ISPE
EQQISSPE----RQ---------PS------------------------GELEEK-TDRM
PQDELGQ-ERRDLEPENREEGQERR---------------VSDIQSKA---GISRESLVS
STTEDILFQK---DKSAPVYPLTMTWSFGWNSSLPVYYIREERQRVLLYVCAHTAIIYNV
FR

PF00400 // ENSGT00390000013370_0_Domain_0 (663, 704)

NNQYHLQGHANIISCLCVS--EDRRWIATADKGPDCLVIIWDSFTGIPVHT--IFDSC
PEGNGIMAMAMTHDAKYLATISDA-----EVQ-KVCIWKWTLAVETPACTLELPTEYGVQ
--NYVTFNPTNNKELVSNSKTRAIYYAWYE--------------------ERDTLAH--S
APVLTEKTFNKLVGKFSQSIFHLNLTQILSATMEGKLVVWDIHRPPSSA-----------
---------STFLGFPYIKPCKLVHLQKEGITVLTTIDSYIVTGDIKGNIKFYDHTLSIV
NWYSHLKLGAIRTLSFSKTPATPPTEKSNYP------PDCTLKGDLFVLRNFIIGTSDAA
VYHLTTDGTKLEKLFVEPKDAICAISCHPYQPLIAIGSICGMIKVWNYENKQYLFSRVFE
KGLGVQSLTYNPEG-------------------------------------ALLGAGFTE
GTVYILDAMSLENESPEPFKYSRTSVTHISFSHDSQYMATADR---SFTVAVYMLVVRNG
QRVWEYLARLRSHRKSIRSLLFGVYLDSNEPRLLSLGTDRLLIEYDLLRSYKDHLEVLDI
HHTDQGCYPTCMVWYPPLTREL-----FLLICNSGYKVKLFNATTKMCRKT----LLGPA
------YGSPIEQ--------TQVLPVRSMAELQK-RYLVFINRDKVGLQILPVDGNPHK
TSAIV

PF00400 // ENSGT00390000013370_0_Domain_4 (1386, 1417)

CHPNGVASMAVSYDGRYAFTAGGHDRSVVQWKITLSVLEAAVSLGGEDLTPFYGL
LSGGREGKFYRELEDYFYYSQLRSQGIDTMETRKVSEHICLSELPFVMRAIGFYPSEEKI
DDIFNEIKFGEYVDTGKLIDKINLPDFLKVYLNHKPPFGNTMSGIHKSFEVLGYTNSKGK
KAIQREDFLRLLVTKGEH----MTEEEMLDCFASLFGLNPEGWKSEPAT-SSVKG--SEI
CLEEELPDEITAEIFATEILGLTISEDSGQDGQ---------------------------
------------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------SMVW
VATPGMLFL-K--NRDSSLHPLDLSWVFGYNSSLAVHSLMDGEDRVLLYISSHTVVIHDI
LRNRQ

PF00400 // ENSGT00390000013370_0_Domain_0 (666, 704)

FHLQGHTNVISCLCVS--EDKRWVATADKGPDALIIVW

ENSGT00390000013370_0_Linker_0_1 (704, 1040)

DSYSGVPVRT--IFESH
SED-GVCAIAISQDAKYLVTISAA-----AVQ-EVCVWRWTLPTGKPMCSTELKPEFGYQ
--DYVIFNPQNPHEFVSNSKTQVIFYLWVIS--------------------HSLHSH--T
AWLLSPQTFKCLVGQFSQSVFHVNNTQALTGTSAGKLVVWDMDNPCTLPE----------
---------ELPAKPHGVTATKVVSLQKESLTVLTVLESCIVTGDVKGQVKFYDGQLRLL
TIYSHDKVGPIQSISFSTILRDRPTCRDMSQLSD-----SSNSVSLTLNRNFILSTSDAT
MFHVATDSTSFERIMAEAK

PF00400 // ENSGT00390000013370_0_Domain_1 (1040, 1067)

KAVNAIACHPQEPLVAVGSHCGLLKVW

ENSGT00390000013370_0_Linker_1_2 (1067, 1083)

DYKQTQYLISRIFT
E-

PF00400 // ENSGT00390000013370_0_Domain_2 (1083, 1145)

AGIQCLSYDPEG-------------------------------------HFLAAGFTD
GSVY

ENSGT00390000013370_0_Linker_2_3 (1145, 1162)

ILDAISLQS-ICKEFQF

PF00400 // ENSGT00390000013370_0_Domain_3 (1162, 1182)

SQGPVTHISFSHDSKYIATADE---TYSVTVYKRVLQNG
SRCWEHLAGLESHYKPIRSILFGVHSDSNEPRLLSLGEDRQLVEYDLNSSIKDHLVVTHR
DRLEQVAVPLCLTWYPQLSTES-----FFLTANNCYKMKLYNMTTKMCRKT----LLGPT
------YGSPLEK--------IQILPRTSSADPQQ-HYLVYITKDKVGLQMLPVDGNPHK
SSAFICHPDGASDFAISHDGRYIFTAGGKERTFMKWKVNLHSLNAAAFLGGEDLIPFYNL
LDGGREGKFFRELEDYFYYVQLCNQGIKTLETRQVSTHIPLEEIPSVMRAIGFYPSEEEI
EDMINEVKFSKYAETGEEVTKINLDDFIKLYINHRPALGLSMKTIQRAFQVLGYDNKKGD
KVIDRGDFLSLLQCR----GEQMTEDELAECLTTLLGRRPRKEGSELDT-CHPTG--AAA
LTEEEIPTEITAEIFVADILGLPIAE----------------------------------
------------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------MSDAEEAPGEATGENG
ETEMKEEE--------EPNPNYK-EVENLQQESK-DDTLAWRESQEE---------ERKM
-GEEEGEEEKE------------EEEEEGKE-----------------DKKIVM---EET
-------E-EVAGEAQEKEASGIQEET----------------------TV--E-PQEVT
ES-----I--------------IRLETQI-TDSQSI---------------------TSG
IFPP---LR------HLGSLQPLPPRFNQQASTRHEPLRPAHTQMESHYVSQ----AGLE
LVSSSNPP----AS---------AS------------------------QSVEIIGNEQM
ETEGDGE-LRMQFWVYRKIEGREQW---------------LTPVIPAL---WETKPGQEP
STSGD---SPTSASQSAGITVVTMTWSFGWNSSLPVYYIREEKQRVLLYVCAHTAIIYNV
LRNN

PF00400 // ENSGT00390000013370_0_Domain_0 (665, 704)

QHHLQGHANIISCLCVS--EDRRWIATADKGPDCLVIIW

ENSGT00390000013370_0_Linker_0_1 (704, 1035)

DSFTGIPVHT--IFDSC
PEGNGIRAMAMTHDAKYLATISDA-----EVQ-KVCIWKWTLAVETPACTFELPKEYGVQ
--NYLTFNPTNNKELVSNSKTQAIYYAWYE--------------------ERDTLAH--S
APLLTEKTFNKLVGKFSQSIFHLNLTQILSATMEGKLVVWDIHRPPSSA-----------
---------STFLGFPYIKPCKLVHLQKEGITVLTTIDSYIVTGDIKGNIKFYDHTLSIV
NWYSHLKLGAIRTLSFSKTPATPPTEKSNYP------PDCTLKGDLFVVRNFIIGTSDAA
VYHLTTDGTKLEQL

PF00400 // ENSGT00390000013370_0_Domain_1 (1035, 1067)

FVEPKDAICAISCHPYQPLIAIGSICGMIKVWNYENKQYLFSRVFE
KGLGVQSLTYNPEG-------------------------------------ALLGAGFTE
GTVYILDAMSLENESPEPFKYSRT

PF00400 // ENSGT00390000013370_0_Domain_3 (1165, 1192)

SVTHISFSHDSQYMATADR---SFTVAVYMLVVRNG
QRVWEYLARLRSHRKSIRSLLFGVYLDSNEPRLLSLGTDRLLIEYDLLRSYKDCLEVLDI
HHTDQGCYPTCMVWYPPLTREL-----FLLICNSGYKVKLFNSTTKMCREQ----TLGRK
------DRSKIGE--------TGMLTSMSKMQMKT-RYHFFTNQDEVGLQILPVDGNPHK
TSAIVCHPNGVAGMAISYDGRYAFTAGGHDRSVVQWKITLRVLEAAVSLGGEDLTPFYGL
LSGGREGKFYRELEDYFYYSQLRSQGIDTMETRKVSEYICLSELPFVMRAIGFYPSEEKI
DDIFNEIKFGEYVDTGKLIDKINLPDFLKVYLNHKPPFGNTMSGIHKSFEVLGYTNSKGK
KAIRREDFLRLLVTK----GEHMTEEEMLDCFASLFGLNPEGWKSEPAT-SSVKG--SEI
CLEEELPDEITAEIFATEILGLTISEDSGQDGQ---------------------------
------------------------------------------------------------

MSDKEDNPSEVKEKSV--------------------------------------------
---------------------------------DD-------------------------
IPSQDPESQRKESMEKEEELKETEGTENTTEITTEE----VTESMAT---------STSQ
DLQ--SQSVPE-ENE-----LIYSE--ALTTTS-PQSSLEISSDKSEETEKSRGVS--TH
FEESS-EKTATEVSGQAPTELSDE----IFT------ESSGQPPIESSDEVFTESSGQVP
TESTGEAPTESTGE---APTESIQEAFTESSEHAPTESVEEAFTEWMGEAPPESVEEVFT
ES-----SGQIA---------TESAEEVFTESSG-----------------QLPTESAEA
AFTEPGPQAFGEWSGQSLP-EPS---VST--DYTADETEV---LFQKPSIRV--------
--FKGSSIR----V---------F---------------------------------EGT
PYSGE-E-ETYEEEP--------------------------SPKEQRS---VKLQDSLVY
FTKEDDLFKEK--TKVAKIYPLNLTWCYGWNSSLPVYNMRDEDQRVVLYTCSHTVVLFDV
FKNSQ

PF00400 // ENSGT00390000013370_0_Domain_0 (666, 693)

LHLQGHSNVITCMAVS--EDRRWIATA

ENSGT00390000013370_0_Linker_0_1 (693, 1034)

DKGPQCLVIVWDCFSGIPVHT--IFDSC
PDGNGIKALAMTNDAKFIVTIDDQ-----TFQ-RVCIWRWTVDTETPACSVSLEPDCGVQ
--DYIIFNPRDYKELVSNSKTQLLFYEWDE--------------------AKGVLEF--S
KPVLTEKTFNKIVGKFSQSIFHFVTRQILSATMEGKLVVWDLHPPPRSYTS---------
------------LEKLRIKACKLVHLQPDGLTVLTAVDSYFVTGDIRGHIRFYDYKLSLV
NWYSQFKLSPIKMLSFSKDPLVPVGDKSNFP------SDCTLPGDPFMVRNFIIGTSDAK
VFHLTTDGTNLEE

PF00400 // ENSGT00390000013370_0_Domain_1 (1034, 1067)

VLIESKEAIYAIDCHPYKPLIAIGAACGLLKVWNYRKKMYVVSRIFE
EGLGIQSLAFNLEG-------------------------------------FLLGAGFTE
GTVYIMDAVSLKNEAPRPFKYSKGSVTLITFSNDSQFLATADV---YFTVAVYKIVIKNG
EKVWEYLARLHSHTKKIQSLMFGVQLDNNETRLLSLGKDRLLIEYDLMNCNKDHLEILDI
HRTDQEALPNCMVWYPPITRES-----FLLICNSGYKVKLFNSTTKMCRKT----LIGPT
------YGSPIQQ--------VQILPPKGPDDQKD-RYLAFINKDKVGLQILPVDGNPHK
TA

PF00400 // ENSGT00390000013370_0_Domain_4 (1383, 1416)

AIICHPDGVSNMSLSYDGTYVFTAGGDDHTVLQWEINLEALEAAVYLGGEDLTPFYGL
LDGGREGEFYKELEDYFYYSQLRSQGIDTMETRKVSTHIPLSELPFVMRAIGFYPSEEEI
DDMLNEVKFSEYVDTGELVDAIDLPDFVKVYINHRPPFGHTINEIRNCFKILGRVHNNGA
VSIKREDFLELLLTK----GEHMTEEELSDCFSTLFGLNPEGWKSEPAT-LSYKG--PDI
CLEEVLPEEITAEIFATEILGLPIPDEDT-------------------------------
------------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------MSDTEENPLEE-----S--------RETPMMKCLLTSDP
G----------------------------------------NSVSSSGLHEHLQ--THTH
AHT-HTHTHHINTHIKEKRNPYTKFSNYE-----------------------MPRRVV--
--P-----------SSLWR-QVS---PSF---LEIGSPEV-SQIYKDISMTV----DNTE
EA--------------------------------------------------GQK-PEDI
LDQGKDK-AR------------------------LSLEERRKLFQSKG---LSAEESLVS
ISTEDTLFQ-K--EEDSKVYPLSMTWSFGWNSSLPVYYMRED-RRIILYICAHTAVMYDV
FR

PF00400 // ENSGT00390000013370_0_Domain_0 (663, 704)

NTQYHLQGHPNIISCLCVS--EDRRWIATADEGPDCLIIIWDAFTGIPVHT--IFDSC
PEGNGMRSIAITRDSKFLATISDS-----ATQ-KVCIWKWTLAVETPACTLELPKEYGFQ
--ENLIFNPFNNKEMVSNSKTQAVYYYWFE--------------------DKGILAH--S
APVLTEKTFNKLVGKFSQSVFHLKLPQVLSATKEGKLVVWDIHYPSSSSSSSS-------
-------SSAAVSAFPFIKPRKLVHLQKEAIMVLMTVDSYIVTGDIKGNIKFYDHTLSVV
NWYSNFKLGAIRTLSFSKTTPSPPTEKSNLP------TDCTLRGDLFVVRNFIIGTFDAT
VYHMTVDGTKLEKLFVEPRDAVHAISCHPYQPLIAVGSVCGMIKVWDFEKKVYLFSRTFE
KGLGVQCLTYNPEG-------------------------------------ALLGAGFTE
GTVYILDAMSLENESPEPFKYSKSSVSHCCFSHDSNYMATADV---NFTVAVYGVVVKNG
QRVWEYLARLRSHQNSIRSLLFGVHLDSNEPRLLSLGKDRFLIEYNLVKSCKDHLDVLDI
HRTDQGNYPTCMIWYPPLTREL-----FLLICNSGYKVKLFNATTKMCRKT----LLGPA
------YGSPIEH--------AQVLPVKSTLELQK-RYLVFINKDKVGLQILPVDGNPHK
TCAIICHPNGVAGMALSYDGRFAFTAGGQDRSVVQWKINLGALEAAVSLGGEDLTPFYGL
VSGGREGKFYRELEDYFYYSQIRSQGIDTMETRQVSEHICLSELPFVMRAIGFYPSEEKI
EDMFNEIKFSEYVETGKLIDKINLPDFLKVYLNHRPPFGNTMDGIQNSFNVLGYTNSEGK
KAIRREDFLNLLLTK----GEHMTEEEMFDCFSTLFGLTPEGWKSEPAA-TSIKG--PEI
CLQKELPEEITAEIFTTEILGLALSDSSEQLTQ---------------------------
------------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------RKREGEDEEEE----IRE-EGED-
-------NPNYQKIEEREEVSGFNRKE-----------------------EE-E-KENII
QSTQEEDEGQDE------------------EDRS-----------------------SS-
---------------------GPTLSLDPEDA-------------RLLELSQ--------
-AELSDFE--------------------------------------------PDLSEDQL
PPDKLGE---------KPNQKPRRGDRRQEKQVSYMKHGG-----------KAPRQSLVS
STTDDALFKK---QDSAKVFPLTMTWTFGWNSTLPVFSLRGDNRRVLLYACAHTAVIYDV
FQ

PF00400 // ENSGT00390000013370_0_Domain_0 (663, 692)

NNQHHLQGHTNVISCLCVS--EDRRWIAT

ENSGT00390000013370_0_Linker_0_1 (692, 1030)

ADKGPDCLIIIWDSYTGIPVHT--LFDSC
PDGSGIRAIAITHDAKYLATISDG-----SVQ-KICIWKWTLAVETPACMLELNKDYGVQ
--SYLTFNPTNNKELVSNSKTQAVYYFWHE--------------------EKNVLAH--S
APLLTEKTFNKLVGKFSQSVFHLNLTQILSATMEGKLVVWDIHRPPPSA-----------
---------TTFLGFPYIKPCKLVHLQKEGITVLTTVDSYIVIGDIKGNIKFYDRSLSIA
NWYSHLKLSAIRTLSFSKTPAPTSAEKSSYP------QDSTLKGDLFIMRNFIISTSDAT
VYHLTADGT

PF00400 // ENSGT00390000013370_0_Domain_1 (1030, 1067)

KLEKLFVEPKDAVYAVSCHPYQPLLAIGSLCGMIKVWDYEAKTYLFSRVFE
KGLGIQSLNYNPEXXXXXXXXXXXXXXXXXXXXXXXXX-------------------X--
XXXXXXXXXXXX------XXXXX-XXXXXXX-X--XXXXXX-X---XXXXXXXXXXX---
--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXIEYNLPKTYKDHLEVLDI
HRTDQGSHPTCMVWYPPLTKEL-----FLLICNSSYKVMLFNSTTKMCRXX----XXXXX
------XXXXXXX--------XXXXXXXXXXXXXX-XXXXXXXXXXVGLQILPVDGNPHK
TSAMICHPSGVVGMTLSYDGCYAFTAGGEDHSVAQWEINLXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXX-XXX-XX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXEHMTKEEMLEGFAMLFGLTPEGWKSEPAA-SAFRG--TEI
SLEEELPDEITAEIFATDILGLTVSEDVSQNGQ---------------------------
------------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------EGE---EEKPNYK-EVEK-QQESKEDDTLAWRESQEE---------EEEW
-EEEEEEEEE-------EEE-EGEEE----------------EEA---VREEM-------
-------E-EKAGAAQEEVAAGVEEET----------------------TV--K-PQEIA
KS-----V--------------ISLERLRPTASQSV---------------------LSG
TFSK---TH------SGSESKHS---LQAERSETNELSGITSSQLKFLDLDQ----ISSE
EQLISYPE----GQ---------PS------------------------SELGEK-TDQI
PQVEWGQ-ERRDSQPEMGDGGGKG----------------RKDTRRKT---GSPKDSLVA
TTTEDILFQQ---GDSANVYPLTMTWSFGWNSSLPVYYIRDENQRVLLYVCAHTAIIYNV
SKND

PF00400 // ENSGT00390000013370_0_Domain_0 (665, 704)

QHHLQGHPNVISCLCIS--EDRRWIATADKGPECLVIIW

ENSGT00390000013370_0_Linker_0_1 (704, 1036)

DSFTGILFHLAHDIDSC
PEGNGIRAIAITRDAKYLATISDA-----EIQ-KVCIWRWTLAAETPACSLDLPKEYGFQ
--NYLTFNPTNNRELVSNSKTQVIYYLWYE--------------------ERDILAH--S
APLLTEKTFNKLVGKFSQSIFHLNLTQILSATMEGKLVVWDIYRPPSSA-----------
---------STSSDLAYIKPCKLVHLQREGITVLTTVDSYIVTGDIKGNIKFYDQTLSIV
NWYSHFKLSSIRTLSFSKTPATPPTEKSSYL------PDCTLKGDLFVVRNFIIATSDAT
VYHLTTDGTKLEKLF

PF00400 // ENSGT00390000013370_0_Domain_1 (1036, 1067)

VEPKNAICAISCHPYQPLIAIGSFCGMIKVWDYEKKKYLFSRVFG
KRLGVQSLTYNPEG-------------------------------------VLLGAGFTE
GTVYILDAMSLENEIPEPFKYSR

PF00400 // ENSGT00390000013370_0_Domain_3 (1164, 1192)

NSVTHISFSHDSQYMATADV---NFTVAVYRVVVRHG
QRVWEYLARLRSHRKSIQSLLFGLHLDINEPRLLSLGKDRLLIEYNLVKSYKDHLEVLDI
HRTDQGDYPTCMVWYPPLTKEL-----FLLICNSGYKVKLFNSSTKMCRKT----LLGPV
------YGSPIEQ--------TQVLPVKTTMDLQK-RYLVFINRDKVGLQILPVDGNPHK
TSAIICHPSGVAGMALSCDGRYAFTSGGQDRSVVQWEINLSALEAAVSLGGENLTPFYGL
VSGGREGKFYRELEDYFYYSQLRSQGIDTMETRKVSEHICLSELPFVMRAIGFYPSEEKI
EDMFNEIKFGEYVDTGKLIDKINLPDFLKVYLNHRPPFGNTMSGIQRSFNILGFTNSNGK
KAIRREDFLKLLLTK----GEHMTEEEMSDCFASLFGLNPEGWKSEPAA-SSVKG--SEI
CFEEELPDEITAEIFTTEILGLTVSEDFRQDPV---------------------------
------------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------MSDAEEAPRESTGQNG
ETEMKEEE--------EPNPNYK-EVENPQEELK-DDTLAWRESQEEE---------RKK
-GEEEGEEEEE---------------EEG------------E-----EDKEIAM---EET
-------Q-EKAGEAQEEEASGIQKET----------------------TV--E-PQEMK
KS-----M--------------TSLETQI-TDSQSI---------------------TSA
IFPT---TQ------RGSESKPS---LQPEDSEAD----------EFLDLDQ----ISPE
EQQMSSPE----RQ---------PS------------------------GELED--TNQR
PQDELGR-ERRDLEPEKKEEGQERS---------------VSSTQSIA---GISRESLVS
TTTEDVLFQK---DKSAPVYPLTLTWSFGWNSSLPVYYVREEKQRVLLYVCAHTVIIYNV
FR

PF00400 // ENSGT00390000013370_0_Domain_0 (663, 704)

NHQYHLQGHANIISCICIS--EDRRWIATADKGPDCLVIIWDTFTGIPVHT--IFDSC
PEGNGIRAMAMAHDAKYLATISDA-----EVQ-KVCIWKWTLAVETPACTLELPKEYGFQ
--NYLTFNPTNNKELVSNSKTQAIYYAWYE--------------------ERDTLAH--S
APLLTEKTFNKLVGKFSQSIFHLNLTQILSATMEGKLVVWDIHRPPSSA-----------
---------STFLGFPYIKPCKLVHLQKESITVLTTIDSYIVTGDIKGNIKFYDHTLSIV
NWYSHLQLSAIRTLSFSKTPATPPTEKSNYP------PDCTLKGDLFVIRNFIIGTSDAT
MYHLTTDGTKLEKLFVEPKDAICAISCHPYQPLIAIGSICGMIKVWNYEKKRYLFSRVFE
KGLGVQSLTYNPEG-------------------------------------ALLGAGFTE
GTVYILDAMSLENESPEPFRYSRTSVTHISFSHDSQYMATA-------------------
------------------------------------------IEYDLLRSYKDHLEVLDI
HRTDQGCYPTCMVWYPPLTREL-----FLLICNSGYKVKLFNATTKMCRKT----LMGPA
------YGSPIEQ--------AQVLPARSMAELPK-RYLVFINRDKVGLQILPVDGNPHK
TTAIVCHPNGVAGMALSYDGRYAFTAGGHDRSVVQWKINSSVLEAAVSLGGEDLTPFYGL
LSGGRKGKFYRELEDYFYYSQLRSQGIDTMETRKVSEHICLSELPFVMRAIGFYPSEEKI
EDIFNEIKFGEYVDTGKLIDKINLPDFLRVYLNHRPPFGNTLSGIHKSFEVLGYTNSKGE
KAIRREDFLKLLVTK----GEHMTEEEMLDCFASLFGLNPEGWKSEPAT-SSVKG--SEI
CLEEELPDEITAEIFATGILGLTISEDSGQDGQ---------------------------
------------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------MSDAEEAPREATGENG
ETEMKEEE--------EANPNYK-EVEDPQQESK-DDTLAWRESQEE---------ERKT
-GEEEGEE------------------EEGKE-----------------DKKIVM---EET
-------E-EKAGEAQEKEASGIQEET----------------------TV--E-PQEVT
ES-----T--------------SRLEAQI-TDSHSI---------------------TSG
IFPK---TQ------RGSKSKLS---LQLDDAETDELLRDLSTQLEFLDLDQ----ISPE
EQQISSPE----RQ---------PS------------------------GELEEK-TDRM
PQDELGR-ERRDLEPENREERQERR---------------LSDIQSKA---GISRESLVS
STTEDILFQKDEKDKSAPVYPLTMTWSFGWNSSLPVYYIREEKQRVLLYVCAHTAIIYNV
FR

PF00400 // ENSGT00390000013370_0_Domain_0 (663, 704)

NNQYHLQGHANIISCLCIS--EDRRWIATADKGPDCLVIIWDSFTGIPVHT--IFDSC
PEGNGIRAMAMTHDAKYLATISDA-----EVQ-KVCIWKWTLAVETPACTLELPTEYGVQ
--NYITFNPTNNKELVSNSKTRAIYYAWYE--------------------ERDTLAH--S
APLLTEKTFNKLVGKFSQSIFHLNLTQILSATMEGKLVVWDIHRPPSSA-----------
---------STFLGFPYIKPCKLVHLQKEGITVLTTIDSYIVTGDIKGNIKFYDHTLSIV
NWYSHLKLGAIRTLSFSKTPATPPTEKSNYP------PDCTLKGDLFVLRNFIIGTSDAA
VYHLTTDGTKLEKLFVEPKDAICAISCHPYQPLIAIGSICGMIKVWNYENKQYLFSRVFE
KGLGVQSLTYNPEG-------------------------------------ALLGAGFTE
GTVYILDAMSLENESPEPFKYSRTSVTHISFSHDSQYMATADR---SFTVAVYMLVVRNG
QRVWQYLARLRSHRKSIRSLLFGVYLDSNEPRLLSLGTDRLLIEYDLLRSYKDHLEVLDI
HHTDQGCYPTCMVWYPPLTREL-----FLLICNSGYKVKLFNATTKMCRKT----LLGPA
------YGSPIEQ--------TQVLPVRSMAELQK-RCLVFINRDKVGLQILPVDGNPHK
TSAIVCHPNGVAGMAVSYDGHYAFTAGGHDRSVVQWKITLSVLEAAVSLGGEDLTPFYGL
LSGGREGKFYRELEDYFYYSQLRSQGIDTMETRKVSEHICLSELPFVMRAIGFYPSEEKV
GRTKTRS------------------NPVETYVPSKCPHGGRLAN----------------
---------------VDGMSEHMTEEEMLDCFASLFGLNPEGWKSEPAT-SSVKG--SEI
CLEEELPDEITAEIFATKILGLTISEDSGQDGQ---------------------------
------------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------MSDAEEAPREATGENG
ETEMKEEE--------EPNPNYK-EVENLQQESK-DNTLVWREAQEE---------ERKT
-GEEEG-----------------EKEEEGKE-----------------DKKIVM---EET
-------E-EVAGEAQEKEASGIQEET----------------------TV--E-PQEVT
ES-----M--------------SRLETQI-TDSQSI---------------------TSG
IFPK---TQ------RGSKSKPS---LQLEDAETDELLGGLSTQLEFLDLDQ----ISPV
EQQISSPE----RQ---------PS------------------------GELEEK-TDRM
LQDELGR-ERRDLEPENREEGQESR---------------VSDIQSEA---GISRESLVS
STTEDILFER---DERAPVYPLTMTWSFGWNSSLPVYYIREEKQRVLLYVCAHTAIIYNV
FR

PF00400 // ENSGT00390000013370_0_Domain_0 (663, 704)

NNQHHLQGHANIISCLCVS--EDRRWIATADKGPDCLVIIWDSFTGIPVHT--IFDSC
PEGNGIRAMAMTHDAKYLATISDA-----EVQ-KVCIWKWTLAVGTPACTLELPKEYGVQ
--NYLIFNPTNNKELVSNSKTQAIYYAWVS--------------------VSHH------
---AQPITFNKLVGRFSQSIFHLNLTQILSATMEGKLVVWDIHRPPSSA-----------
---------STFLGFPYIKPCKLVHLQKEGITVLTTIDSYIVTGDIKGNIKFYDHTLSIV
NWYSHLKLGAIRTLSFSKTPATPPTEKSNYP------PDCTLKGDLFVLRNFIIGTSDAA
VYHLTTDGTKLEKLFVEPKDAICAISCHPYQPLIAIGSICGMIKVWNYENKQYLFSRVFE
KGLGVQSLTYNPEG-------------------------------------ALLGAGFTE
GTVYVLDAMSLENESPEPFKYSRTSVTHISFSHDSQYMATADR---SFTVAVYMLVVRNG
QRVWEYLARLRSHRKSIRSLLFGVYLDSNEPRLLSLGTDRLLIEYDLLRSYKDYLQVLDI
HRTDQGCYPTCMVWYPPLTREL-----FLLICNSGYKVKLFNATTKMCRKT----LMGPA
------YGSPIEQ--------TQVLPVRSTAELQK-RYLVFINRDKVGLQILPVDGNPHK
TSAIVCHPNGVAGMAVSCDGRYAFTAGGHDRSVVQWKITLSVLEAAVSLGGEDLTPFYGL
LSGGREGKFYRELEDYFYYSQLRSQGIDTMETRKVSEYICLSELPFVMRAIGFYPSEEKV
GRMKTRAATGCA-------------------IYKKQPLGT--------------------
------------NII----GEHMTEEEMLDCFASLFGLNPEGWKSEPAT-SSVKG--SEI
CLEEELPDEITAEIFATEILGLTISEYSGQDGQ---------------------------
------------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------MSDAEEAPGEATGENG
ETEMKAEE--------EPNPNYK-EVENLQQESK-DDTLAWRESQEE---------ERKM
-GEEGGEEEEE---EEEKEE-EEEKEEEGKE-----------------DKKIVM---EET
-------E-EVAGEAQEKEASGIQEET----------------------TV--E-PQEVT
ES-----M--------------IRLETQI-TDSQSI---------------------TSG
IFPK---AQ------RGSKSKPS---LQLEDAETDELLRGLSTQLEFLDLDQ----ISPE
EQQISSPE----RQ---------PS------------------------GELEEK-TDWM
LQDELGR-ERRDLEPENREEGQESR---------------VSNIQSEA---GISRESLVS
STTEDILFER---DESAPVYPLTMTWSFGWNSSLPVYYIREEKQRVLLYVCAHTAIIYNV
LR

PF00400 // ENSGT00390000013370_0_Domain_0 (663, 704)

NNQHHLQGHANIISCLCVS--EDRRWIATADKGPDCLVIIWDSFTGIPVHT--IFDSC
PEGNGIRAMAMTHDAKYLATISDA-----EVQ-KVCIWKWTLAVETPACTLELPKEYGVQ
--NYLTFNPTNNKELVSNSKTQAIYYAWYE--------------------ERDTLAH--S
APLLTEKTFNKLVGKFSQSIFHLNLTQILSATMEGKLVVWDIHRPPSSA-----------
---------STFLGFPYIKPCKLVHLQKEGITVLTTIDSYIVTGDIKGNIKFYDHTLSIV
NWYSHLKLGAIRTLSFSKTPATPPTEKSNYP------PDCTLKGDLFVVRNFIIGTSDAA
VYHLTTDGTKLEKLFVEPKDAICAISCHPYQPLIAIGSICGMIKVWNYENKQYLFSRVFE
KGLGVQSLTYNPEG-------------------------------------ALLGAGFTE
GTVYILDAMSLENESPEPFKYSRTSVTHISFSHDSQYMATADR---SFTVAVYMLVVRNG
QRVWEYLARLRSHRKSIRSLLFGVYLDSNEPRLLSLGADRLLIEYDLLRSYKDCLEVLDI
HHTDQGCYPTCMVWYPPLTREL-----FLLICNSGYKVKLFNSTTKM-------------
-----------------------------------------------------FDGNPHK
TSAIVCHPNGVAGMAISYDGRYAFTAGGHDRSVVQWKITLSVLEAAVSLGGEDLTPFYGL
LSGGREGKFYRELEDYFYYSQLRSQGIDTMETRKVSEYICLSELPFVMRAIGFYPSEEEI
DDIFNEIKFGEYVDTGKLIDKINLPDFLKVYLNHKPPFGNTMSGIHKSFEVLGYTNSKGK
KAIRREDFLRLLVTK----GEHMTEEEMLDCFASLFGLNPEGWKSEPAT-SSVKG--SEI
CLEEELPDEITAEIFATEILGLTISEDSGQDGQ---------------------------
------------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
--------QK------KHK-RAEEQ--KYNMQQESEEEDTLAGKQSQEEEAAGEETEEQA
QEAYEEEEVAGEETEEQAQEAYK-EEEAAGEETEEQVEEAYEEEETEEQAQEAYKEEEVA
-GEETEEQAQEA--YEEEEA-AGEETEEQTQEAYKEEEVAGEETEEQVEEAYEE---EET
-------EEQAQEAYEEEEAAGEETEE----------------------QAQAA-AEEVE
AE-----E--------------EIMEEQARAAAEEE--------------------EAAR
AQED---MR---------LERHSNHSL---QPKRSRFSGDLSSQFESLDLDQ----SRSD
KSWSSYPE----KL---------PS------------------------GEIEET-TSQK
PEDEREQEQ-RVQ-------EPRKGEWRKKRRVSYFKH-EKKAFQSKA---KVRKESLVS
TTKEDGLFKK---DDSASVYPLSMTWSFGWNSSLPVYYIRGETQRVLLYVCAHTVVIYDV
FKNDQ

PF00400 // ENSGT00390000013370_0_Domain_0 (666, 704)

RHLQGHPNAISCLCIS--EDRRWIATADKGPDCLIIIW

ENSGT00390000013370_0_Linker_0_1 (704, 1037)

DSFSGIPVHT--IFDSC
PKDSGIRAIAITRDAKYLATISDA-----EVQ-QICIWKWTLAVEKPACTLDLNKEYGFQ
--NYLTFNPTNNKELVSNSKTQAIYYSWQE--------------------ERNVLVH--S
APLLTGKTFNKLVGKFSQSVFHLNLTQLLSATMEGKLVVWDIHRPPPAA-----------
---------SSHSGFPHIKPCKLVHLQKEGITVLTTVDSYIVTGDIKGNIKFYDHTLSIV
NWYSQFKLSAIRTLSFSKIPPASPTEKSDYP------PDCTLKGDSFIVRNFIIGTFDAT
VYHLTTDGTRLEKLFV

PF00400 // ENSGT00390000013370_0_Domain_1 (1037, 1067)

EPKDAICAIACHPYQPLIAIGSLCGMIKVWDYNKKKYIFSRVFE
KGLGVQSLTYNPEG-------------------------------------ALLGAGFTE
GTVYILDAMSLENGSPQPFKYSRT

PF00400 // ENSGT00390000013370_0_Domain_3 (1165, 1192)

NVTHISFSHDSQYMATADV---SFTVAVYKVVVKNG
HRIWEYLARLRSHRKSIQNLLFGVHLDNNEPRLLSLGKDRLLIEYNLLRSYKDHLEVLDI
HRTDQGFYPTCMIWYPPLTREQ-----FLLICTSGYKVKLFNSTTKMCRKT----LLGPT
------FGSPIEH--------IQLLPVRTTSELQK-RYLVFMNRDKV-------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------GHPNVISCLCLS--EDRRWIATADKGPDCLIIIWDSFTGIPVHT--IFDSC
PEGNGIGAIAITRDAKFLATISDA-----EVQ-KVCIWKWTLAAETPACTLELPAEYGVQ
--HYIMFNPTNNKELVSNSKTQAIYYSWXX--------------------XXXXXXX--X
XXXXXXXTFNKLVGKFSQSVFHLNLTQILSATMEGKLVVWDIHRPPPSS-----------
---------ATFVGFPYIKPCKLVHLQKEGITVLTAVDGXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------XXXXXXXXXXXXXNFIIGTADAT
VYHLTTDG

PF00400 // ENSGT00390000013370_0_Domain_1 (1029, 1067)

TRLEKLFVEPKDAICAVSCHPYQPLIAIGSVCGMIKVWNYEEKRYLFSRVFE
KGLGVQSLTYNPEXXXXXXXXXXXXXXXXXXXXXXXXX-------------------X--
XXXXXXXXXXXX------XXXXX-XXXXXXX-X--XXXXXX-X---XXXXXXXXXXX---
--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXIEYNLRKSYRDHLEVLDI
HRTDQGNYPTWMVWYPPLTKEL-----FLLICNSGYKVKLFNSTTKMCRKT----LLGPT
------YGSPIEQ--------ALVLPARTTADLQK-RYLVFINRDKVGLQILPVDGNPHK
TAAIVCHPSGVAGMALSYDGCYVFTAGGLDRSVVQWKINVXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXX-XXX-XX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXEHMTEEEMTDCFATLFGLNXXXXXXXXXX-XXXXX--LEL
CLEEELPDEITAEIFT-EILGLTIAEDSGQHGQG--------------------------
------------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------MSLESAISEPFRYSR

PF00400 // ENSGT00390000013370_0_Domain_3 (1164, 1183)

SSVTHISFSHDSQYMATAD

ENSGT00390000013370_0_Linker_3_4 (1183, 1382)

V---SFTVAVYVVRVKHG
QRVWEYLARLRSHRKSIRSVLFGVHLDSNEPRLLSLGRDRLLIEYNLLKSYKDHLAVLDI
HRTDQGSYPTCMVWYPPLTKEL-----FLLICNSGYKVKLFNSATKMCRKT----LLGPV
------YGSPIEQ--------IQILPVKSTLELQK-RYMVFINRDKVGLQILPVDGNPHK
T

PF00400 // ENSGT00390000013370_0_Domain_4 (1382, 1416)

SALICHPNGVASMALSYDGCYAFTAGGQDRSVVQWEINLSALEAAVSLGGEDLTPFYGL
VSGGREGKFYRELEDYFYYSQLRSQGIDTMETRKVSEHICLSELPFVMRAIGFYPSEGKI
EDMFNEIRFSEYVDTGKLIDKINLPDFFKVYLNHRPPFGNTMSGIQQSFDILGFTNSKGE
KAIRREDFLNLLQTK----GEHMTEEEMTDCFATLFGLNPEGWKSEPAA-SSVKG--SEI
CLEEELPDEITAEIFTTEILGLTVSQDSRQDPRIIEAEQ--SF-----------------
------------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-------------MSDTEENPLEESR----------------EKKEEEEKEE----EEKE
EEEKEEEKEKE-KEKEEYNPSF--EEDALQQSL-TEGSLSW----EESQEDGEGLE---E
WVEKEEQREGEEVRGEEESEVRGGEEEEGWEE-----EKSSEEEKSEESERSKERGGEEE
GQE--KEEAEHEGE---REE-GRE------------EEEKEKSVEREEEEEEEEEEDNVL
KTT-ERKAGRAKEEKKEKQNKTALVDNI-----------------------------V--
--I-----------SH--E-PPR---SSS---SLADSPEV-SQIYKDISMKV----DDTE
EA--------------------------------------------------SQK-PEDI
LAQGKDE-AR------------------------LSLEERRKLFQSKG---LSAEESLVS
VSTEDTLFQ-K--EEDSKVYPLSMTWSFGWNSSLPVYYMQED-RRVILYICAHTAVMYDV
FR

PF00400 // ENSGT00390000013370_0_Domain_0 (663, 704)

NTQYHLQGHPNIISCLCVS--EDRRWIATADEGPDCLIIIWDSFTGIPVHT--IFDSC
PEGNGMRSIAITRDSKFLATISDS-----ATQ-KVCIWKWTLAVETPACTLELPKEYGFQ
--DNLVFNPVNNKELVSNSKTQAVYYYWFE--------------------DKGILAH--S
APVLTEKTFNKLVGKFSQSVFHLKLPQVLSATKEGKLVVWDIHYPSSTS-----------
---------SAISAFPFIKPRKLVHLQKEAITVLMTIDSYIVTGDIKGNIKFYDHTLSVV
NWYSNFKLGAIRTLSFSKTIPSPPTEKSNLP------TDCTLRGDLFVVRNFIIGTFDAT
VYHMTVDGTKLEKLFVEPRDAVHAVSCHPYQPLIAVGSICGMIKVWDFEKKVYLFSRTFE
KGLGVQCLTYNPEG-------------------------------------ALLGAGFTE
GTVYILDAMSLENESPEPFKYSKSSVSHCCFSHDSNYMATADV---NFTVAVYMVVVKNG
QRVWEYLARLRSHQNSIRSLLFGVHLDSNEPRLLSLGKDRFLIEYNLVKSCKDHLDVLDV
HRTDQGNYPTCMIWYPPLTKEL-----FLLICNSGYKVKLFNATTKMCRKT----LLGPA
------YGSPIEH--------AQVLPVKSTLELQK-RYLVFINKDKVGLQILPVDGNPHK
TCAIVCHPNGVAGMALSYDGRFAFTAGGQDRSVVQWKINLGALEAAVSLGGEDLTPFYGL
VSGGREGKFYRELEDYFYYSQIRSQGIDTMETRQVSEHICLSELPFVMRAIGFYPSEEKI
EDMFNEIKFSEYVETGKLIDKINLPDFLKVYLNHRPPFGNTMDGIQNSFNVLGYTNSEGK
KAIRREDFLNLLLTK----GEHMTEEEMIDCFSTLFGLTPEGWKSEPAA-TCING--PEI
CLQKELPEEITAEIFTTEILGLTLSDSSEQLIQ---------------------------
------------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------MSDAEEAPREATGENG
ETEMKEEE--------EPNPNYK-EVENLQQESK-DNTLVWRESQEE---------ERKM
-GEEEGE-------------------EEGKE-----------------DKKIVM---EET
-------E-EVAGEAQEKEASGIQEET----------------------TV--E-PQEVT
ES-----M--------------SRLETQI-TDSQSI---------------------TSG
IFPK---TQ------RGSKSKPS---LQLEDTETDELLRGLSTQLEFLDLDQ----ISPE
EQQISSPE----RQ---------PS------------------------GELEEK-TDQM
LQDELGR-ERRNLEPENREEGQESR---------------VSDIQSEA---GISRESLVS
STTEDILFER---DESAPVYPLTMTWSFGWNSSLPVYYIREEKQRVLLYVCAHTAIIYNV
FR

PF00400 // ENSGT00390000013370_0_Domain_0 (663, 704)

NNQHHLQGHANIISCLCVS--EDRRWIATADKGPDCLVIIWDSFTGIPVHT--IFDSC
PEGNGIRAMAMTHDAKYLATISDA-----EVQ-KVCIWKWTLAVETPACTLELPKEYGVQ
--NYLTFNPTNNKELVSNSKTQAIYYAWYE--------------------ERDTLAH--S
APLLTEKTFNKLVGKFSQSIFHSNLTQILSATMEGKLVVWDIHRPPSSA-----------
---------STFLGFPYIKPCKLVHLQKEGITVLTTIDSYIVTGDIKGNIKFYDHTLSIV
NWYSHLKLGAIRTLSFSKTPATPPTEKSNYP------PDCTLKGDLFVLRNFIIGTSDAA
VYHLTTDGTKLEKLFVEPKDAICAISCHPYQPLIAIGSICGMIKVWNYENKQYLFSRVFE
KGLGVQSLTYNPEG-------------------------------------ALLGAGFTE
GTVYILDAMSLENESPEPFKYSRTSVTHISFSHDSQYMATADR---SFTVAVYMLVVRSG
QRVWEYLARLRSHRKSIRSLLFGVYLDSNEPRLLSLGTDRLLIEYDLLRSYKDCLEVLDI
HRTDQGCYPTCMVWYPPLTREL-----FLLICNSGYKVKLFNATTKMCRKT----LMGPA
------YGSPIEQ--------TQVLPVRSTAELQK-RYLLFINRDKVGLQILPVDGNPHK
TSAIV

PF00400 // ENSGT00390000013370_0_Domain_4 (1386, 1417)

CHPNGVAGIAVSYDGRYAFTAGGHDRSVVQWKITLSVLEAAVSLGGEDLTPFYGL
LSGGREGKFYRELEDYFYYSQLRSQGIDTMETRKVSEYICLSELPFVMRAIGFYPSEEKI
DDIFNEIKFGEYVDTGKLIDKINLPDFLKVYLNHKPPFGNTMSGIHKSFEVLGYTNSKGK
KAIRREDFLRLLVTK----GEHMTEEEMLDCFASLFGLNPEGWKSEPAT-SSVKG--SEI
CLEEELPDEITAEIFATEILGLTISEYSGQDGQ---------------------------
------------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------MSDAEENP--------
-LEAEEDGETE-TEEEEYDTNYYKEVENMQQES-KDDTVAW----GDSQEEERRKG----
----------EE--GEEE-------------------EEEEEEETVSASELEEDSGTAQ-
------EE---------VAA-GIQ------------EETTAEL-----------------
-------QGAT--------KSTISVERHITDYQ------------------SAMSETFSQ
TYS-----------ASE-----S---KHS---LQSEHPRSLGSQLEFLGLDL----TSSE
EQETDSAER----W---------LS------------------------DEPGEK-TSQM
PQDEPEQ-DRGGLEPE----------------GEKKKEKAVSYFQPKA---IVSEDSLVS
TTTEDMLFQ-K--NDSDSVYPLTLSWSFGWNSSLPVYYIRDKNQRVLLYASTHTAVIYNV
L

PF00400 // ENSGT00390000013370_0_Domain_0 (662, 692)

RNSQRHLQGHLNVISCLCVS--EDRRWIATADKGPNSLIIIWDSFTGIPVHT--IFDSC
PDGSGIRAIAMTFDAKYLATISDA-----EIQ-KVCIWRWTLAVETPACSLDLPKEYGFQ
--SYLTFNPTNNKELVSNSKTQAIYYSWNE--------------------RGNVLTH--S
APVLTEKTFNKLVGKFSQSIFHLNLTQVLSATMEGKLVVWDIHRPPPAA-----------
---------SASLGPPYIKPCKLVHLQKESITVLTAVDSYIVTGDIKGSIKFYDHTLAIV
NWYSHFKLGSIRTLSFSRTPASPPTEKSNYP------PDCTLKGDPFVVXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXX-------------------------------------XXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDA---SFTVAVYKVRVRNG
QRVWEYLARLRSHRQSIRSLLFGVHLDSNEPRLLSLGKDRLLIEYNLLKSCRDHLEVLDI
HQTDQGNYPTCMIWYPPLTKEL-----FMLVCNSGYKVKLFNSTTKMCRKT----LLGPV
------YGSPIEQ--------IQILPVKTAMELQK-RYLVFINRDKVGLQILPVDGNPHK
TSAIICHPDGVAGMALSCDGRYAFTAGGQDRSVIQWEINLSALEAAVSLGGEGLTPFYSL
VSGGREGKFYRELEDYFYYSQLRGQGIDTMETRKVSEHICLSELPFVMRAIGFYPSEEKI
EDMFNEIRFSEYVDSGEIVDKINLPDFLKVYLNHRPPFGNTMYAIERSFNILGYTNSKGK
KVIRREDFLKLLLTK----GEHMTEEELSDCLATLLGLNPEGWKSEPAA-ASTKG--SQL
CLEDELPDEITAEIFATEILGLALSSSSRREPTDHQ------------------------
------------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------TMTWTYGWNSSLPVFYIHEERHRVLVYVCAHTVVIYNT
F

PF00400 // ENSGT00390000013370_0_Domain_0 (662, 694)

RNKQYHLQGHPNVISCLCVS--EDRRWIATAD

ENSGT00390000013370_0_Linker_0_1 (694, 1029)

RGPGCLIIIWDSFTGIPVHT--IFDSC
PDGNGIRAIAMTRDAKYLATISDA-----EAQ-KVCIWKWTLAVETPACTLELPADYGLQ
--NYVTFNPANNKELVSNSKTQVIYYSWDE--------------------EKDTLVH--S
APVLTEKTFNKLVGKFSQSVFHLHLTQILSATMEGKLVVWDVQRS---------------
------------GGSPYIKPCKLVHLQREGITVLTTVDSYIVTGDVRGNIKFYDRSLSIV
NWYSHFKLSSIRTLSFSKTPAAPPTEKSNFP------PDCTLKGDLFVVRNFIIGTSDAT
VYHLTTDG

PF00400 // ENSGT00390000013370_0_Domain_1 (1029, 1067)

TKLEKLFMEPKDAICAISCHPYQPLIAIGSVCGMIKVWDYEKKKYLFSRAFE
KGLGVQSLTHNPEG-------------------------------------ALLGAGFTE
GTVYILDAMSLE

PF00400 // ENSGT00390000013370_0_Domain_3 (1153, 1194)

NESRKPFQYSRGSVTHISFSHDSQYMATADV---NCTVAVYMIVVRNG
QRVWEYLARLRSHRKSIRSLLFGVHLDSNDPRLLSLGKDRLLIEYNLRRSCRDHLEVVDI
HRTDQGDYPTCMVWYPPLTKEL-----FLLICNSGYKVKLFNSTTKMCRKT----LLGPT
------C-SPIEQ--------TQVLPARTAKELXX-XXXXXXXXXXVGLQILPVDGNPHK
TWAIVCHPNGVAGMALSYDGSYAFTAGGHDRSVVQWKINLSTLEAAVSLGGDDLTPFYDL
VPGGREGRFYTELEDYFYYSQLRSQGIDTMEDRQVSDHISLSELPYVMRAIGFYPSEEKI
ANMFNEIKFSEYVNTGKIIDKINLPDFLKVYLNHRPPFGNTMSGIQQTFEVLGFTNSKGQ
KAIRREDFLKLLQTK----GEHMTKEEMLDCFATLFGLNPEGWGSEPAA-ISFKG--SEI
CLEEELPEEITAEIFTTEILGLAISEDSESGQ----------------------------
------------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------MSDAEENPLEETEEYG
EIEMQEEDD--EE---EEYPNFE-GLENVQKELKEVNTLAWIESPEE---------EEEE
-EGEEEGREFG---EEVEAE-NGEE---------------GE-EA---VKEEVG----E-
-------D-TAEALEEEEEASGAQEES----------------------TV--E-PEEIT
TS-----I--------------ISLERFTQPDSQTV---------------------LSE
ISLV---KK------SGSESKLS---LQSEFLETFELPRSPGSQLEFLDLDV----TTSG
EPLISFPE----RQ---------PS------------------------GEL-----DQR
PQDELEEEEGRDLEPERGDLEQEK------------SKKSEKESQPKA---RITKASLVS
TATEDILFQR---RESANMYPLTMTWSFGWNSSLPVYYLRE-NQRVLLYASGHTGVIYNV
LKNN

PF00400 // ENSGT00390000013370_0_Domain_0 (665, 704)

QYHLQGHPNVISCLCIS--EDRRWVATADKGPDCLIIIW

ENSGT00390000013370_0_Linker_0_1 (704, 1037)

DSFTGIPVHT--IFDSC
PRDNGIRAMAMTRDAKYLATISDA-----EIQ-KVCIWKWTLAVETPACTLDLPKEYGFQ
--NFILKNYNNNKELVSNSKTQVIYYTWYP--------------------EGGILVH--S
APLLTEKTFNKLVGKFSQSVFHLNLTQILSATMEGKLVVWDIYRPLPSA-----------
---------SSSMGFPHIKPCKLVHLQKEGITVLTTVDSYIVTGDIRGNIKFYDHTLSIV
NWYSHFKLSSIRSLSFSKTPAAPPAENTNYP------PDCTLKSDDFVVRNFIIGTSDAS
VYHLTVDGTKLEKLFV

PF00400 // ENSGT00390000013370_0_Domain_1 (1037, 1067)

EPRDAICAISCHPYQPLIAIGSFCGMIKVWDYEQKKYLFSRVFE
KGLGVQSLTYNPEG-------------------------------------ALLGAGFTE
GTVYILDAMSLESAISEPFRYSR

PF00400 // ENSGT00390000013370_0_Domain_3 (1164, 1183)

SSVTHISFSHDSQYMATADV---SFTVAVYVVRVKHR
RRVWEYLARLRSHRKSIRSILFGVHLDSNEPRLLSLGRDRLLIEYNLLKSYKDHLAVLDI
HRTDQGSYPTCMVWYPPLTKEL-----FLLICNSGYKVKLFNSTTKMCRKT----LLGPV
------YGSPIEQ--------IQILPVKSTLELQK-RYVVFINRDKVGLQILPVDGNPHK
TSALICHPNGVAGMALSYDGCCAFTAGGQDRSVVQWEINLSALEAAVSLGGEDLTPFYGL
VSGGREGKFYRELEDYFYYSQLRSQGIDTMETRKVSEHICLSELPFVMRAIGFYPSEGEI
EDMFNEIRFSEYVDTGKLTDKINLPDFFKVYLNHRPPFGNTMSGIQQSFDILGFTNSKGE
KAIQREDFLNLLHTK----GEHMTEEEMTDCFATLFGLNPEGWKSEPAA-SSVKG--SEI
CLEEELPDEITAEIFTTEILGLTISQDSGQDPR---------------------------
------------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------MSDAEENPLEKTEKDG
GTEMEEEEE----EEEEYNPDYLKE-EDMQQEL-EEDTLAGKESQEEEDAEETEEQ----
--------EQE------------E---E---------EDAGEEMEE--------------
-------EVL---AAEEEEYAGAQEET----------------------RVE-TFVTDSL
LA-------------------------------------------------------MSG
TFPD------------------SKHSLQP---EASKFSRGLSLQSEFLNLDQ----NGLD
KQQSSSPEK-------------QPSG-------ELEGT---------TSQKLYEPG----
------Q-ERTR-EPGK-----------------------GXXXXXXXXXXXXXXXXXXX
XXXXXXXX-XX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXX
--NYLSFNPANNRELVSNSKTQAIYYSWQEE--------------------RNILAH--S
APLLTEKTFNKLVGKFSQSVFHLNLTQVLSATMEGKLVVWDI-HRPPPSA----------
---------SSPLGFPYIKPCKLVHLQKEGITVLTTVDSYIVTGDIRGNIKFYDHTLSIV
NWYSQFKLSTIRCLSFSKTPLAPPTEKSDFP------PDCTLKGDSFIVRNFIIGTSDAT
VYHLTTDG

PF00400 // ENSGT00390000013370_0_Domain_1 (1029, 1067)

TKLEKLFVEPKGAICAIACHPYQPFIAIGSLCGLIKVWNYEKKSYLFSRVFE
KGLGVQCLTYNPEG-------------------------------------VLLGVGFTE
GTVYILDAMSLENGSPQPFKYSRTNVTHISFSHDSQYMATADV---SFTVAVYKVMVKNG
QRVWEYLARLRSHRKSIQNLLFGGHLDSNETRLLSG-KDRLLIEYDLPKSYKDHLEVLDI
HRTDQGCYPTCMVWYPPLTREL-----FLLICNSGYKMKLFNSITKMCRKT----LLGPT
------YGSPIEK--------IQILPVKTASELQK-RYLVFMNKDKV

PF00400 // ENSGT00390000013370_0_Domain_4 (1368, 1417)

GLQILPVDGNPHK
TTSVVCHPDGGAGITVSYDGCCIFTAGGADRSVVQWKVNLSALEAAVSLGGEDLTPFYGL
VTGGREGKFYRELEDCFYYSQLRSQGIDTMESRAVSQHVCLSELPFVMRAIGFYPSEEKI
EDMFNEVKFGEYVETGKIVDKISLPDFLKIYINHRPPFGNTMSGIQHSFDVLGFTNSEGK
KVIQREDFLKLLQTK----GEHMTQEEMSNCFATLFGLNPEGWKSEPAT-SSFK------
------------------------------------------------------------
------------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------LFPQSLSWALGYNSSLAVHSLAGGEDRVLLYVCSHTAVIHDI
L

PF00400 // ENSGT00390000013370_0_Domain_0 (662, 692)

GGQQYHLQGHANTISCLCVS--EDRRWVAT

ENSGT00390000013370_0_Linker_0_1 (692, 1043)

ADGGPDPLVIVWDTFSGIPVRT--IFDSH
PGG-GVAAVAISRDARYLVTISAG-----RAQ-KVCVWRWTSPTESPVCSTELRPEFGLQ
--DFVVFNPQNPHEFVSNSKTQVIFYLWSDA--------------------SLQ--Y--S
TPPLTKQTFNSVVGHFSQSAFHFNNTQALTGTSAGKLVLWDTARALSLSE----------
---------EAQVQPHSTKATKLVPMQRSSITVLMVLESCIVTGDVKGRVKFYNGRLQLL
ACYSHSGVGPICSISFSKPPPEPPDAASACSSTGSQPFTT---------GNFILSTSDAT
VLHVATDGTNFEKIMEEAKKAT

PF00400 // ENSGT00390000013370_0_Domain_1 (1043, 1067)

TAIACHPRQALLAVGSHCGLLKVW

ENSGT00390000013370_0_Linker_1_2 (1067, 1082)

DYQQPKYLVSRIFT
E

PF00400 // ENSGT00390000013370_0_Domain_2 (1082, 1147)

-AGIQCLSYDPEG-------------------------------------CFLAAGFTD
GSVYIL

ENSGT00390000013370_0_Linker_2_3 (1147, 1152)

DAISL

PF00400 // ENSGT00390000013370_0_Domain_3 (1152, 1194)

QS-CCEAFRFSQGAVTHISFSHDSEYLATADE---KYAVTVY

ENSGT00390000013370_0_Linker_3_4 (1194, 1378)

KRVLQNG
QRCWEHLAGLHSHYKPIRSILFGVQLDSNEPRLLSLGEDRQLVEYDLSSSSKDQLVISHR
DRVEQVAVPLCLAWYPQFGTES-----FILTANSCYKMKLYNTTTKMCRKT----LLGPT
------YGSPLEK--------IQILPTRSTTDPQK-CYLAYVTKDKVGLQILPVDGN

PF00400 // ENSGT00390000013370_0_Domain_4 (1378, 1417)

PHK
SSAFICHPDGVSDLACSYDGRYIFTAGGNDRTVLKWEVNLNALEAAASLGGEDLVPFYSL
LEGGREGEFFRELEDYFYYVQLRSQGIDALETRQVSTHIPLEEIPSVMRAMGFYPSEEEI
EEMINEVKFSEYVDTGEQVTKINLGDFIKLYINHRPAFGLSMKAIRRAFQVLGYDNENGD
KVIDRGDLLLLLQCR----GEHMTEDELAQCLAALLGRHSAGGRFDLDT-CDPSG--AAA
LTEEEIPEEITAKRFTADILGLPIAEPEKRTVK---------------------------
------------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------MLPQQDSIAAAQEDGA
L---GN---AAAAAPQR---------------------APG------ELEECSSAPSRVW
GAQPGLLFQ-G--EK-QSCHPLSLSWALGYNSSLAVHSME---DGMLLYICAHTVVIHDV
LGS

PF00400 // ENSGT00390000013370_0_Domain_0 (664, 704)

RQYHLQGHANAISCLCVS--EDRRWVATADQGPDPLVIVWDAFSGIPVRT--IFDSH
AGS-GVCAIAISRDAKCLVTISTG-----RVQ-RVCVWRWTHPDESPVCDVELSPEFGFQ
--DFVIFNPQNPYEFVSNSKTQVIFYLWGDA--------------------GLQ--Y--S
TPTLTRQTFGSAVGHFTQSAFHFDATRALTGTSAGKVVVWDVERKRGLAK----------
---------EPQGRLHGMKATKLVPLQEESVTVLMVLESCIVTGDVRGQVKFYDGHLQLL
ACYEHSATAPIRSISFSKTPPDPPSASCT----SSPPFTA---------RNFILSTSDAT
VLRVATDGTDFEKVMEEAKKAVMAIACHPRQAWLAMGSHCGLLKVWDYQQPQLLVSRMFP
S-A

PF00400 // ENSGT00390000013370_0_Domain_2 (1084, 1145)

GIQCLSYDPEG-------------------------------------SFLAAGFID
GSVHVLDAISLLP-CCEVFRFSRGPVTHVHFSHDSEYLATADE---KYAVTVYKRVLQNE
RRCWEHLAGLHSHYKPIRSILFGIQLDGSEPRLLSLGEDRQLIEYDLSSSSKDQLVVLHR
HRVEQDAVPLCLAWYPQFSTES-----FILTANSCYKMKLYNATTKMCRKT----LLGPT
------YGSPLEK--------MQILPR-SAAQPQK-HYLAYITKDKVGLQILPIDGNPHK
SSAFICHPDGASDLAISYDGRYIFTAGGSDRTVLKWEVNLNALEAAASLGGEDLVPFYRL
LEGGQDGEFFRELEDYFYYVQLHSHGIDMLETRQVSTYIPLEEIPSLMRAMGFYPSEEEI
EEMLNEVKFSEYVDTGEQVTKINLGDFIKLYINHRPAFGLSMKTIRQAFQVLGYDNENGD
KVIDRGDLLSLLQCR----GEHMMEDELALCLSALLGRHPKGGRSDLDM-CDPSG--AAA
LMEEEIPEEITAERFTAGILGLSIAEPEKRAVK---------------------------
------------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------MFEDE--SRPLADHPLSLSWVFGYDNKLPVFNLLDDDRRVILYVAGHTAVIHDI
FGNK

PF00400 // ENSGT00390000013370_0_Domain_0 (665, 694)

QYLLQGHSSCVSCICVS--EDKRWIVTADRSPESLIIIWDGYSAVPVHT--IFDSH
PGG-GVSAVAISHNSLFVATVGAEE----VQQ-KTRIWDWTTGETTPSCSVDLLPEYSFQ
--HYVAFSSRDHNELVSNSETQVIFYIWYTGKR----------------EDCDVLHY--F
APVLTEKTFDRSVGLFSQSLFHFSTPQAITGTMEGKMALWGPIAPPSKDP----------
---------ALNVKPYNMKVIKLVHLQREGISVLAVTDGNFVTCDTKGRVKFYDGDLQLV
HWYSNLKVGPIRSISFNRNPPCP-VDVSKYP------MSCTLTGAPFVLRNFILSTSNSL
VVHIKPEGLKISKCLEEPKDVVHAIACHPSKPLMAKGSLCGLLKVWHYKLDKYLVSRIFK
S-ESIQALCYNHNG-------------------------------------CLLAVGFAS
GAIRLLDSISLENDHPEPMKFSKGPITIMTFSHKSQYFATAANDGQPFALGVSKFTKKKP
SMTWVVCHFKKK---TIIS-QYDKTTKLHIPETLNLAAQPLIHASTFIQQKEKKNKVLI-
------RGRGIIVFYPIAARPPSLSILILIIIIITTTTPPFSPKNPLRRGIEAQPCLGLL
------EGGPAP---------------FPSSALCV---PTSTSASQVGLQVLPVDGNPHK
SCTVICHPTGASNLACSYDGCHLFTAGSHDFTVMKWDVNLNALEAVVFLGGKDLIPYYNL
LEGGREGLFFKELEDYFYYAQLIHQGINTMEPRKVSTHIPLEQIPFVMQAMGFFPTEDEI
ENMLNEVKFSEYLETGKQVTSINLGDFIKLYINHRPAFGLSRNEINHAFQILGYEDEDGE
PTINRDDLLLLLQNT----GEHFTETELAECLTTLLGVNPEGGRGEVGT-YDPTG--AEV
FIEEDIPEEITAGHFTMNLLGLPLPEPTLGESE---------------------------
------------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------NLAWCYGWNSSLPIYNMRDENQRIVLY-CSHTAVLFDA
FKNSQHHLQXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXIPVHT--IFDSC
PDGNGIKAMAMTKDAKFLVTIDDA-----TFQ-KVCIWRWTVDTETPACSITLEPDMGVQ
--EYIIFNPGNHTELVSNSKSRLLYYEWDE--------------------ANDILQL--S
MPVLTEKTFNKIVGKFSQSVFHFAARQILTATTEGKLVVWDLHPPPRSYTS---------
------------LEVLRIKACKLVHLQKDAFTVLTSVDRYFVTGDVRGHIRFYDSKLALV
NWYSQFKLSPIVMLSFSKDPL--PCDKSNFP------SDCTLPGNPFIVRNFIIGTSDAR
VYHLTTDG

PF00400 // ENSGT00390000013370_0_Domain_1 (1029, 1067)

TKLEEVLIDPKDAIHAIACHPYKPLIAVGSVCGMLKMWNYRKKMYVVSRIFE
DGLGIQSLTFNPEG-------------------------------------FLLGAGFTE
GTVYIMDAVSLKNEAPEPFKYSRGNVTLISFSHDSQFLATADV---NFTVAVYKLMEKNG
EKVWEYLARLHSHHKKIQSLLFGIQQDNNDPRLLSLGKDRLLIEYDLLNSTKDHLEVLDI
HRTDQEAIPKCMVWYPPLTRES-----FLLICNSVYKVKLFNSTTKMCRKT----LIGPT
------YGSAIER--------VLVLPEKATNDPQK-RYLAFINKDKVGLQILPVDGNPHK
TAAIICHPDGVSNVTLSYDGTYVFTAGGDDHTVLQWEINLXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXI
DDMLNEIKFSEYVDTGKLVDSINLPDFVKVYVNHRPPFGQTMNDIRNAFKVLGYLNKDGE
MAIRREDFLELLLTK----GEHMTEEELSDCFSTLFGLNPEGWKSEPAT-LAYKG--SSI
CLEEELPEEITAEIFTADILGLPIPEDIKGH-----------------------------
------------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------DE----QQ--
--VPTEPQWESK---------------APARLSSSTNLK---QGMQQIGQE-AQESDRKN
L---RDKDEENSA--DQ---------------------EILS--IEAGAEMSCEESSLVF
SATPGLLFE-E--NEHIKTHPISLSWAFGYNSSLPVYSLLDEEQRVILYVSSHSAVIHDV
HGNR

PF00400 // ENSGT00390000013370_0_Domain_0 (665, 704)

QYHLQGHSNSISCLCIS--EDRRWVATADQGPDNLIIVW

ENSGT00390000013370_0_Linker_0_1 (704, 1041)

DAFSGIPVHT--IFGSH
PED-GVGAIAISQDAKYLVTVGAS-----KIQ-RVCIWKWTSPEDKPMFSIELPPAFGYQ
--SYIVFNPKNHKELVSNSKTQVLFYMWSDD--------------------TSGLHY--S
APPLTDRTFDKTVGLFSQSVFHFSNLQALTATSGGKLVVWDIVCSPSRPA----------
---------SLCVKPHNMKAIKLMYVQKDALTVLTASDSYFVTCDVKGHVKFYDGQLQLV
NWYSHFKLGPIQSISFSKSPPRPSSNNSNYSSS------CTINSQPFIIRNFILSTRDAT
VLHFTAKGSKLDKLMEEAKE

PF00400 // ENSGT00390000013370_0_Domain_1 (1041, 1067)

AVNAIACHPSQPLIAIGSHCGLLKVW

ENSGT00390000013370_0_Linker_1_2 (1067, 1083)

DYMQTKYLYSRIFM
E-

PF00400 // ENSGT00390000013370_0_Domain_2 (1083, 1145)

ASIQCLAYDPKG-------------------------------------TFLVAGFSD
GSVY

ENSGT00390000013370_0_Linker_2_3 (1145, 1163)

ILDSISLED-DCKEFKYS

PF00400 // ENSGT00390000013370_0_Domain_3 (1163, 1182)

RGPVTHISFSHDSQYFATA

ENSGT00390000013370_0_Linker_3_4 (1182, 1384)

DE---KYSVTVYRRILKNG
ERTWEHLAGVHSHYKAIRNIIFGVDLDSDQPRLLSLGEDRLLVEYDLGSSSKDNLAILRR
DRIEQSAVPLCLAWYPPFTPEA-----FILTANNKYKMKLYNATTKMCRKS----LLGPT
------YGSPLEK--------IQILPAANSQDPQK-RYLAYITKDKVGLQILPIDGNPHK
SLA

PF00400 // ENSGT00390000013370_0_Domain_4 (1384, 1416)

FICHPGGVSNLASSYDGCHVFTAGGNDRIVMKWELNINALEATVSLGGEDLIPFYNL
LDGGRDGEFFRELEDYFYYAQLRSQGIDAMETRQVSTHIPLEEVPFVMRAMGFYPSEEKI
EDMINEVKFSEYVDTGKQVTNINLGDFIKLYINHRPAFGLSMKEIQNAFQVLGYSSKNGE
IVINRGDLLEQLQCR----GEHMTEEELAECLTTLLGRNPEGEISEQGT-YDPSG--AAA
LIEEEIPEEITAEIFTADILGLPIPEPDNTETGKNYELPNRIGSAES-------------
------------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MSDPE---ENG
AKETE---------EKEYNQNYK-EVENTCRKSP-DDTSGWRESEEDLGGNQLDRKELRE
---EEEEENAE-------------------------EKEKGEEEEEE-------------
---------ED------KAAAGVQEET----------------------SEERT-PEVKS
T-------------------------------SQYG---------------------LQG
TFLE----------IL--GDTGSKQSLRTDSSGLSELFRGLSSNQDYVNVAQ----VHPE
EQQMG------------------SS------------------------AELGER-AHRE
AQNQLGQ-EERDLGRKQGGAGGGRGKARHRKRISYFLGDEEMGSQAEA---GGSRESLVS
SSTEDTLFQK---DEGTQVYPLALSWLFGWNSSLPVFYIRERSQRVLLYVCGHTAVIYNV
PR

PF00400 // ENSGT00390000013370_0_Domain_0 (663, 704)

NTQHHLQGHRNVISCLCVS--EDRRWIATADKGPGCLIIIWDSFTGIPVHT--IFDSC
PQGNGIRAIAISHDAKYLATVSDA-----DAQ-EVCIWRWTLAVETPACTLELPREHGFQ
--NYLTFNPANNKELVSNSKTQTIYYWWHE--------------------EKDTLVH--S
APLLVENTFNKLVGKFSQSIFHPNSTQILSATLEGKLVVWDIHRCALAP-----------
---------SSLADGPFIRPCKLVHLQREAVSVLTTADGYIVTGDIKGNIKFYDQTLSIA
NWYSHLNLSCIRTLSFSPSPVSPRTEKSNFP------LDCTLKGDLFVVRNFIIATSDAT
VYHLTTDGTRLEKLFVEPKDAVCAISCHPYQPLMAVGSACGVIKVWDYEQKKYLFSRVFE
KGLGVQSLTHNPEG-------------------------------------ALLGAGFTE
GTVYILDAMSLQNEAPEPFKYSRSNVTHVSFSHDSQYMATADV---NFTVAVYMMVVRGG
RRVWEYLARLRSHRQSICSLLFGVYLDSNEPRLLSLGRDRLLIEYNLSRSHKDHLEVLDI
HHTDQGHHPTCMVWYPLLTKEL-----FLLVCDSGYKVKLFNSTTKMCRKT----LLGPA
------YGSPVEQ--------ARVLPVRTALELEK-RYLVFINRDKVGLQILPVDGNPHK
TCAMVCHPDGVAGLALSYDGRYAFTAGGHDCSVVQWKINLSALDAAVSLGGEDLTPFYGL
VPGGREGKFYRELEDYFFYSQIRSQGIDTMETRKVSEHICLSEVPFVMRAIGFYPSEEKI
EDMFNEIKFSEYADTGKLIDRINLPDFLKVFVNHRSPFGNTLSGIRQSFEVLGTPNAQGE
KAVRREVLLQLLLSR----GEHMTQEEMTDCFATLSGLNPEGWKSEPAA-SASRG--SEI
CLEEELPDEITAEVFASDILGLTISEGPGEDGQ---------------------------
------------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------MSDAEEAPGEATGENG
ETEMKEEE--------EPNPNYK-EVENLQQESK-DDTLAWREKMGE---------EEG-
----EEE--------EEKEE-EEEKEEEGKE-----------------DKKIVM---EET
-------E-EVAGEAQEKEASGIQEET----------------------TV--E-PQEVT
ES-----M--------------IHLETQI-TDSQSI---------------------TSG
IFPK---TR------RGSKSKPS---LQLEDAETDELLRGLSTQLEFLDLDQ----ISPE
EQQISSPE----RQ---------PS------------------------GELEEK-TDWM
LQDELGR-ERRDLEPENRDEGQESR---------------VSNIQSEA---GISRESLVS
STTEDILFER---DESAPVYPLTMTWSFGWNSSLPVYYIREEKQRVLLYVCAHTAIIYNV
LR

PF00400 // ENSGT00390000013370_0_Domain_0 (663, 704)

NNQHHLQGHANIISCLCVS--EDRRWIATADKGPDCLVIIWDSFTGIPVHT--IFDSC
PEGNGIRAMAMTHDAKYLATISDA-----EVQ-KVCIWKWTLAVETPACTLELPKEYGVQ
--NYLTFNPTNNKELVSNSKTQAIYYAWYE--------------------ERDTLAH--S
APLLTEKTFNKLVGKFSQSIFHLNLTQILSATMEGKLVVWDIHRPPSSA-----------
---------STFLGFPYIKPCKLVHLQKEGITVLTTIDSYIVTGDIKGNIKFYDHTLSIV
NWYSHLKLGAIRTLSFSKTPANPPTEKSNYP------PDCTLKGDLFVVRNFIIGTSDAA
VYHLTTDGTKLEKLFVEPKDDICAISCHPYQPLIAIGSICGMIKVWNYENKQYLFSRVFE
KGLGVQSLTYNPEG-------------------------------------ALLGAGFTE
GTVYILDAMSLENESPEPFKYSRTSVTHISFSHDSQYMATADR---SFTVAVYMLVVRNG
QRVWEYLARLRSHRKSIRSLLFGVYLDSNEPRLLSLGTDRLLIEYDLLRSYKDCLEVLDI
HRTDQGCYPTCMVWYPPLTREL-----FLLICNSGYKVKLFNSTTKMCRKT----LMGPA
------YGSPIEQ--------TQVLPVRSMAELQK-RYLVFINRDKVGLQILPVDGNPHK
TSAIVCHPNGVAGMAISYDGRYAFTAGGHDRSVVQWKITLSVLEAAVSLGGEDLTPFYGL
LSGGREGKFYRELEDYFYYSQLRSQGIDTMETRKVSEYICLSELPFVMRAIGFYPSEEKI
DDIFNEIKFGEYVDTGKLIDKINLPDFLKVYLNHKPPFGNTMSGIHKSFEVLGYTNSKGK
KAIRREDFLRLLVTK----GEHMTEEEMLDCFASLLGLNPEGWKSEPAT-SSVKG--SEI
CLEEELPDEITAEIFATEILGLTISEDSGQDGQ---------------------------
------------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------MSDTEETSIEETGEDE
EAEMEEEE---FE---DYNPDYK-EVKNMQQGSEEDALE-Q---------------RDAW
-EGDE---------------------------------------------IVME---ETA
-------T-KAGAAQEEEKASGVQEVT----------------------AA--E-DQEVV
KS-----I--------------DSLERLTGSQLSMT---------------------SGL
PEPE---TP------RGSESTHS---LQSEDSGTRTLISQ-----IELDVDQ----ISSD
EEPFSSPE----TQ---------PS------------------------SELEEK-IYQM
LQDKLGQER-GGLGPEKGE------------------------GRPKK---GVSGESLVS
TTTEDILFQK---KESSGVYPLTMTWSYGWNSSLPVYYIREGSQRVLLYVCAHTAVLYNV
FQ

PF00400 // ENSGT00390000013370_0_Domain_0 (663, 704)

NNQYHLQGHPNVISCLCVS--EDRRWIATADKGPDCLIIIWDSFTGIPVHT--IFDSC
PEGSGIRAIAMTHDAKYLATISDA-----EVQ-KVCIWKWTLAAETPACSLQLPKEYGFQ
--NYLIFNPTNNKELVSNSKTQAIYYVWYE--------------------ERDILAH--S
APLLTEKTFNKLVGKFSQSVFHLNLTQILSATREGKLVVWDIHHAPSSS-----------
---------SSFSGFPYIKPCKLVHLQKEGISVLTTVDRYIVTGDIKGNIKFYDHTLSIV
NWYSHFKLSIIRSLSFSKTPAPPPTEKSNYP------PGCTLKGDLFIVRNLIIGTSDAT
VYHLTTDGTKLEKLFVEPKDAICAISCHPYAPLIAIGSICGMIKVWDYAKKKYLFSRVFG
KGLGVQSLTYNPEG-------------------------------------ALLGAGFTE
GTVYILDAMSLENESPEPFKYSRTSVTHISFSHDSQYMATADV---SFTVAVYMRVVKNG
QRVWEYLARLRSHHKSIRSLLFGVHLDTNEPRLLSLGRDRLLIEYNLLKSYKDHLEVLDI
HHTDQDSHPTCMVWYPPLTKEL-----FLLICNTGYKVKLFNSTTKMCRKT----LLGPI
------YGSPVEQ--------TQVLPVKSTVELQK-RFLVFINRDKVGLQILPVDGNPHK
TCAIVCHPNGVAGMALSYDGCYAFTAGGQDRSVVQWKINLSVLEAAVSLGGEDLTPFYGL
MSGGREGKCYRELEDYFYYSQLHSQGIDTMETRKVSEHICLSELPFIMRAIGFYPSEEKI
DDMLNEIKFSEYVDTGKLIDKINLPDFLKVYLNHRPPFGNTMRSIHQSFDVLGYTNSKGE
KAIRREDFLKLLLTK----GEHMTEEEMLDCFATLCGLNSEDWKSEPAS-SSVKG--SKI
CLEEELPEEITAEIFTTEILGLTISEDSKQDGQ---------------------------
------------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------MSDAEEAPRESTGKNG
ETEVKEEE--------GSNPNYK-EVENPQEELK-DDTLAWRESQEEE---------RKK
-GEEEGEEEEE---------------EDG------------E-----EDKEIVM---EET
-------E-AKAGEAQEEEASGIQKET----------------------TV--E-PQEMK
KS-----M--------------TSLETRI-TDSQSI---------------------TSG
IFPE--------------------------------------------------------
-----------------------------------------------------N--TNQR
PQDELGR-ERRDLEPEKREEGQERS---------------VSSIQSIA---GISRESLVS
TTTEDILFQK---DKSAPVYPLTLTWSFGWNSSLPVYYIREEKQRVLLYVCAHTAIIYNV
FR

PF00400 // ENSGT00390000013370_0_Domain_0 (663, 704)

NHQYHLQGHANIISCICIS--EDRRWIATADKGPDCLVIIWDSFTGIPVHT--IFDSC
PEGNGIRAMAMAHDAKYLATISDA-----EVQ-KVCIWKWTLAVETPACTLELPKEYGFQ
--NYLTFNPTNNKELVSNSKTQAIYYAW--------------------------------
-------TFNKLVGKFSQSIFHLNLTQILSATMEGKLVVWDIHRPLSSA-----------
---------STFLGFPYIKPCKLVHLQKESITVLTTIDSYIVTGDIKGNIKFYDHTLSIV
NWYSHLQLSAIRTLSFSKTPATPPTEKSNYP------PNCTLKGDLFVVRNFIIGTSDAT
VYHLTTDGTKLEKLFVEPKDAICAISCHPYQPLIAIGSICGMIKVWNYEKKRYLFSRVFE
KGLGVQSLTYNPEG-------------------------------------ALLGAGFTE
GTVYILDAMSLENESPEPFRYSRTSVTHISFSHDSQYMATA-------------------
------------------------------------------IEYDLLRSYKDHLEVLDI
HRTDQGCYPTCMVWYPPLTREL-----FLLICNSGYKVKLFNATTKMCRKT----LTGPA
------YGSPIEQ--------AQVLPVRSMAELPK-HYLVFINRDKVGLQILPVDGNPHK
TTAIVCHPNGVAGMALSYDGHYAFTAGGHDRSVVQWKINLSVLEAAVSLGGEDLTPFYGL
LSGGREGKFYRELEDYFYYSQLRSQGIDTMETRKVSEHICLSELPFVMRAIGFYPSEEKI
EDIFNEIKFGEYVDTGKLIDKINLPDFLRVYLNHRPPFGNTLSGIHKSFEVLGYTNSKGE
KAIRREDFLRLLVTK----GEHMTEEEMLDCFASLFGLNPKGWKSEPAT-SSVKG--SEI
CLEEELPDEITAEIFATEILGLTVSEASGQDGQ---------------------------
------------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---MERKD----------------------------------------------------
-------R-------------EGSSDDSGFHR-------KGSMER-----IP------EA
-------P-SEPEAPKEP---SAPGES----------------------EVPKE-PQPSK
MS-----KGRR------KDSSHESMKKIAARAIQALKAQMPLEEEELKYLQTLTSVSPAD
SPAP---SPFGSLAIAGGKSEGT---------ERS-----EGAKKVFGELSRQGTVRSPH
STKVSFLE----KK---------PS------------------------IRVYDNG--AF
PYDENEEEE-----------------------EEYEQFGEEEASSSKE---PLLQDSLVY
HSREDGLFREK--TEKDKMYPLSLAWCYGWNSSLPIYNMRDGNDRVVLYACSHTAVLYDA
FK

PF00400 // ENSGT00390000013370_0_Domain_0 (663, 693)

NCQHHLQGHSNVITCMCVS--ENRRWIATA

ENSGT00390000013370_0_Linker_0_1 (693, 1032)

DKGPHCLVIVWDGFSGIPVHT--IFDSC
PEGNGIKAMAMTKDAKFLVTIDDA-----PLQ-RLCIWRWTVDTETPTCSVTLQADIGVQ
--EYIIFNPGNHRELVSNSKTHLLYFEWDDDNE----------------------AIEVS
LPALSEKTFNKIVGRFSQSVFHFAARQILTATLEGKLVVWDLHPPPRS------------
---------YTSLEVLHIKACKLLHLQKDGLTVLTTVDRFFVTGDVKGHIKFYDSKLSLV
NWYSQLKLSPIIMLSFSKDPLLVASNKSSFL------SDCTLPGDPFMVRNFIIGTSNAR
VYHFTADGNKL

PF00400 // ENSGT00390000013370_0_Domain_1 (1032, 1067)

EKVLIEPREAIHAIACHPYKPLIAIGSMCGLLKMWNYRKKMYVVSRIFD
EGLGVQCLTFNPEG-------------------------------------YLLGAGFND
GAVYIMDAVSLKNEISEPFRYSR

PF00400 // ENSGT00390000013370_0_Domain_3 (1164, 1192)

DTVTLISFSHDSQYLATADV---NFTVA

ENSGT00390000013370_0_Linker_3_4 (1192, 1383)

VYMIVIKNG
EKVWEYLARLHSHHKKIQSLLFGVQVDSYEPRLLSLSKDRFLIEYDLLNSGKDHLEVLDI
HRTEQEAIPKCMVWYPPITRES-----FLLVCNSVYKVKLFNSITKMCRKT----LIGPT
------YGSPIKQ--------VLVLPEASSKGSQR-RYLAFVNKDKVGLQILPVDGNPHK
TA

PF00400 // ENSGT00390000013370_0_Domain_4 (1383, 1416)

AIICHPSGVSSMAVSYDGTHVFTAGGEDHSVLQWEINLRALEAAVHLGGEDLTPFYGL
LDGGREGEFYKELEDYFYYSQLRSQGIDTMETRQVSTRIPLSELPFVMRAIGFYPSEEQI
DDMLNEIKFGEYVDTGKLADSIDLPEFVKLYINHRPPFGQTISDIRKAFKILGTPNEDGE
MAIEREHFLELLLTK----GEHMTEEELSDCFTVLFGLNPEGWKSEPAT-LDYKG--SNI
RLEEELPEEITAEIFTSDILGLPIPEDF--------------------------------
------------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------MSDKEEKPLAESRESG
DMDKEEEGEEE-EEEEEYNPSF--EEDRLQQSL-TEGTLSW----EESQEDGEGLE--GK
WIEKEEQIEGKEVRGEEEEMRGKEEREERWEE-----EETGEEEKSEEKEGSKEKGGEEE
EKV--EEEKEKSGE---EGK-DIV------------LEKTEES-----------------
----------------KKYETPIRVGDIV-----------------------ISSESSTS
IYS-----------VAGTP-ESS---KSS---LHSQSPEV-SEIYQDVSMKM----DSLE
EAVVGS------------------Q------------------------EEIGQE-SEGI
SDQEKEE-ARFGK-------------------PFFPMEERQKLFQSKD---LGAKESLVS
TSTEDTLFQ-K--EDDSKMYPLSLTWSFGWNSSLPVYYMRED-RRILLYVCGHTAVIYNV
FKN

PF00400 // ENSGT00390000013370_0_Domain_0 (664, 704)

SQYHLQGHPNIISCFCVS--EDRRWIATADEGPDCLIIIWDAFTGIPVHT--IFDSC
PEGNGIRSIAITRDSKFLATISDA-----ENQ-KVCIWKWTLAVETPTCMLELPKEYGFQ
--EHLIFNPVNNKELVSNSKTQAVYYSWFE--------------------DKGILTH--S
APLLTEKTFNKLVGKFSQSVFHLKLPQILSATKEGKLVVWDIHYPWASSTSASSSAAEAE
ADADSASADSAVSEFPFMKPRKLVHLQKEAITVLTTIDSYIVTGDIKGNIKFYDHTFSIV
NWYSNFKLGAIRTLSFSKTLPSPPTEKSNLP------TDCTLRGDLFVVRNFIIGTFDAT
VYHMTVDGTKLEKLFVEPRDAVHAISCHPYQPLIAVGSVCGIIKVWDFEKKVYLFSRTFE
KGLGVQSLTYNPEG-------------------------------------ALLGAGFTE
GTVYILDAMSLENETSEPFKYSRSSVSHVSFSHDSNYMATADI---SFTVAVYMMVVKNG
QRVWEYLARLRAHHNSIRSLLFGIHLDSNEPRLLSLGTDRFLIEYNLTKSYKDHLEVLDI
HRTDQGNYPTCMIWYPPLTKEL-----FLLICNSGYKVKLFNATTKMCRKT----LLGPA
------YGSPIEH--------AQVLPVKSTLELQK-RYLVFINRDKVGLQILPVDGNPHK
TCAI

PF00400 // ENSGT00390000013370_0_Domain_4 (1385, 1417)

VCHPNGVSGLALSYDGHFAFTAGGQDRSVVQWKINLGALEAAVSLGGEDLTPFYGL
VSGGREGKFYRELEDYFYYSQIRTQGIDTMETRQVSEHICLSELPFVMRAIGFYPSEEKI
EDMFNEIKFSEYVDTGKLIDKINLPDFLKVYLNHRPPFGNTFDGIQKSFDVLGFTNSEGK
KAIQREDFLNMLLTK----GEHMTEEEMFDCFATLFGLSPEGWKSEPAA-SCTKG--PEI
CLEKELPEEITAEIFTTEILGLTLSNHSEQSDQ---------------------------
------------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------MSDAAEAPREATGENG
ETEMKEEE--------EPNPNYK-EVEDPQQESK-DDTIAWRESQEE---------ERKT
-GEEEGEE-------------------EGKE-----------------DKKIVM---EET
-------E-EKAGEVQEKEASGIQEET----------------------TV--E-PQEVT
AS-----M--------------IRLETQI-TDSQSI---------------------TSG
IFPK---TQ------RGSKSKLS---LQLEDAETDELLRDLSTQIEFLDLDQ----ISPE
EQQISSPE----RQ---------PS------------------------GELEEK-TDRM
PQDELGQ-ERRDLEPENREEGQERR---------------VSDIQSKA---GISRESLVS
STTEDILFQK---DKSTPVYPLTMTWSFGWNSSLPVYYIREERQRVLLYVCAHTAIIYNV
FR

PF00400 // ENSGT00390000013370_0_Domain_0 (663, 704)

NNQYHLQGHANIISCLCVS--EDRRWIATADKGPDCLVIIWDSFTGIPVHT--IFDSC
PEGNGIMAMAMTHDAKYLATISDA-----EVQ-KVCIWKWTLAVETPACTLELPTEYGVQ
--NYVTFNPTNNKELVSNSKTRAIYYAWYE--------------------ERDTLAH--S
APLLTEKTFNKLVGKFSQSIFHLNLTQILSATMEGKLVVWDIHRPPSSA-----------
---------STFLGFPYIKPCKLVHLQKEGITVLTTIDSYIVTGDIKGNIKFYDHTLSIV
NWYSHLKLGAIRTLSFSKTPATPPTEKSNYP------PDCTLKGDLFVLRNFIIGTSDAA
VYHLTTDGTKLEKLFVEPKDAICAISCHPYQPLIAIGSICGMIKVWNYENKQYLFSRVFE
KGLGVQSLTYNPEG-------------------------------------ALLGAGFTE
GTVYILDAMSLENESPEPFKYSRTSVTHISFSHDSQYMATADR---SFTVAVYMLVVRNG
QRVWEYLARLRSHRKSIRSLLFGVYLDSNEPRLLSLGTDRLLIEYDLLRSYKDHLEVLDI
HHTDQGCYPTCMVWYPPLTREL-----FLLICNSGYKVKLFNATTKMCRKT----LLGPA
------YGSPIEQ--------TQVLPVRSMAELQK-RYLVFINRDKVGLQILPVDGNPHK
TSAIVCHPNGVAGMAVSYDGCYAFTAGGHDRSVVQWKITLSVLEAAVSLGGEDLTPFYGL
LSGGREGKFYRELEDYFYYSQLRSQGIDTMETRKVSEHICLSELPFVMRAIGFYPSEEKI
DDIFNEIKFGEYVDTGKLIDKINLPDFLKVYLNHKPPFGNTMSGIHKSFEVLGYTNSKGK
KAIRREDFLRLLVTKGEH----MTEEEMLDCFASLFGLNPEGWKSEPAT-CSVKG--SEI
CLEEELPDEITAEIFATEILGLTISEDSGQDGQ---------------------------
------------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------MSQHRQTP---QEMDEPEKDLAAPRENKR
E---PDNTEESPFCPRS---------------------SPLG--YRERHTPHKGFASLVW
GAKPGMLFQ-K--NRDESFHPLELSWVFGYNSSLAVHSLMDGEERVLLYVSSHTVVIHDI
PRNRQ

PF00400 // ENSGT00390000013370_0_Domain_0 (666, 704)

FHLQGHTNVISCLCVS--EDKRWVATADQGPDALIIVW

ENSGT00390000013370_0_Linker_0_1 (704, 1039)

DSYSGIPVCT--IFETQ
SEE-GICAIAISQDAKYLVTISAA-----TVQ-KVCVWRWTLPTEKAICSTELKPEFGYQ
--DYVIFNPQNPHEFVSNSKTQVIFYLWDDS--------------------GLQ--Y--G
APFLSNQTFKCLVGQFSQSVFHFNNTQALTGTSAGKLVVWDMDNPRTLPE----------
---------ELPAKPHGITATKMVSMQKESLTVLQVLESCIVTGDVGGQVKFYDGLLRLL
TIYSHDKVGPIHSISFSTVLRDPPSAPP-------------GSSQPFLTRNFILSTSDAT
MLHVATDSTNFERITEEA

PF00400 // ENSGT00390000013370_0_Domain_1 (1039, 1067)

KKAVNAIACHPQEPLVAVGSHCGLLKVW

ENSGT00390000013370_0_Linker_1_2 (1067, 1083)

EYRQTKYLVSRIFT
E-

PF00400 // ENSGT00390000013370_0_Domain_2 (1083, 1145)

AGIQCLSYDPEG-------------------------------------HFLAAGFTD
GSVY

ENSGT00390000013370_0_Linker_2_3 (1145, 1162)

ILDAISLQS-ICKEFQF

PF00400 // ENSGT00390000013370_0_Domain_3 (1162, 1190)

SQGPVTHISFSHDSKYLATADE---SYSVTVYRRVLENG
SRRWEHLAGLDSHYKPIRSILFGVHPDSNEPRLLSLGEDRQLVEYDLKSSIKDCLVVTHR
DRLEQDAVPLCLTWYPQLSTES-----FFLTANNCYKMKLYNTTTKMCRKT----LLGPT
------YGSPLEK--------IQILPRTSSADPQQ-HYLVYITKDKVGLQMLPVDGNPHR
SSAFICHPDGASDFAISHDGRYIFTAGGKERTFMKWKVNLPALDAAAFLGGEDMIPFYNL
LDGGRDGKFFRELEDYFYYVQLCSQGIITLERRQVSTHIPLEEIPSVMRAIGFYPSEEEI
EEMINEVKFSKYADTGEEVTEINLEDFIKLYINHRPALGLSMKTIQRAFQVLGYDNKKGD
KVIDRGDFLLLLQCR----GEQMTEDELAECLTTLLGRRTRKGESELDT-CDLTG--AAA
LTEEEIPAEITAEIFVRDILGLPIAEPEKK------------------------------
------------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------MSDAEEAPGEATGENG
ETEMKEEE--------EPNPNYK-EVENLQQESK-DDTLAWRESQEE-------------
---------------ERKMG-EEEGEEEGKE-----------------DKKIVM---EET
-------E-EVAGEAQEKEASGIQEET----------------------TV--E-PQEVT
ES-----M--------------IHLETQI-TDSQSI---------------------TSG
IFPK---TR------RGSKSKPS---LQLEDAETDELLRGLSTQLEF-DLDQ----ISPE
EQQISSPE----RQ---------PS------------------------GELEEK-TDGM
LQDELGR-ERRDLEPENRDEGQESR---------------VSNIQSEA---GISRESLVS
STTEDILFER---DESAPVYPLTMTWSFGWNSSLPVYYIREEKQRVLLYVCAHTAIIYNV
LR

PF00400 // ENSGT00390000013370_0_Domain_0 (663, 704)

NNQHHLQGHANIISCLCVS--EDRRWIATADKGPDCLVIIWDSFTGIPVHT--IFDSC
PEGNGIRAMAMTHDAKYLATISDA-----EVQ-KVCIWKWTLAVETPACTLELPKEYGVQ
--NYLTFNPANNKELVSNSKTQAIYYAWYE--------------------ERDTLAH--S
APLLTEKTFNKLVGKFSQSIFHLNLTQILSATMEGKLVVWDIHRPPSSA-----------
---------STFLGFPYIKPCKLVHLQKEGITVLTTIDSYIVTGDIKGNIKFYDHTLSIV
NWYSHLKLGAIRTLSFSKTPATPPTEKSNYP------PDCTLKGDLFVVRNFIIGTSDAA
VYHLTTDGTKLEKLFVEPKDAICAISCHPYQPLIAIGSICGMIKVWNYENKQYLFSRVFE
KGLGVQSLTYNPEG-------------------------------------ALLGAGFTE
GTVYILDAMSLENESPEPFKYSRTSVTHISFSHDSQYMATADR---SFTVAVYMLVVRNG
QRVWEYLARLRSHRKSIRSLLFGVYLDSNEPRLLSLGTDRLLIEYDLLRSYKDCLEVLDI
HRTDQGCYPTCMVWYPPLTREL-----FLLICNSGYKVKLFNSTTKMCRKT----LMGPA
------YGSPIEQ--------TQVLPVRSMAELQK-RYLVFINRDKVGLQILPVDGNPHK
TSAIVCHPNGVAGMAISYDGRYAFTAGGHDRSVVQWKITLSVLEAAVSLGGEDLTPFYGL
LSGGREGKFYRELEDYFYYSQLRSQGIDTMETRKVSEYICLSELPFVMRAIGFYPSEEKI
DDIFNEIKFGEYVDTGKLIDKINLPDFLKVYLNHKPPFGNTMSGIHKSFEVLGYTNSKGK
KAIRREDFLRLLVTK----GEHMTEEEMLDCFASLLGLNPEGWKSEPAT-SSVKG--SEI
CLEEELPDEITAEIFATEILGLTISEDSGQDGQ---------------------------
------------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------MSDAEENPLEETEEYG
EIEMEEEE--------EKYPNDE-GLENMQQELKEDNTLAWRGSQEEGEAER--------
---------------------------EGAE---------GK------------------
---------EEGEEFGKEEAAGAHEET----------------------TV--K-PQEIT
KS-----M--------------ISLERLTPTDSQSI---------------------LSG
TLPK---TY------SGRESKHS---LQSELLETFELPS-MASQLEFLDLDL----TTSA
EQQLSSPE----KQ---------PS------------------------GELAER-TDQR
PQDELGQ-ERRDLEPEKREGRKETR---------------VLYVQPKA---RIPKGSLVS
TATEDILFQK---DDGANVYPLAMTWSFGWNSSLPVYYIQDENQRVLLYASANTAVIYNV
F

PF00400 // ENSGT00390000013370_0_Domain_0 (662, 692)

KNNQHHLQGHPNVISCLCIS--EDRRWVATADKGPECLIIIWDCFTGIPVHT--IFDSC
PEGGGIRAMAITHDAKYLATISDA-----EIQ-KVCIWRWTLAVETPACTLNLPKEYGFQ
--SYLTFNPTNNKELVSNSKTQAIYYMWYE--------------------EGDILVH--S
APLLTEKTFNKLVGKFSQSVFHLNLTQILSATMEGKLVVWDIYRPPPSA-----------
---------STSLGFPHITPCKLVHLQKEGITVLTTVDSYVVTGDIRGNIKFYDHTLSIV
NWYSHFKLSSIRSLSFSKTPATPPTENTNYP------PDYTLKGDLFIVRNFIIGTSDAS
VYHTA-DGTKLXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXX-------------------------------------ALLGAGFTE
GTVYILDAMSLESETPEPFKYSRTSVTHVSFSHDSQYMATADV---SFTVAVYVVRVKNG
RRVWEYLARLRSHRKSIRSVLFGVHLDSNEPRLLSLGRDRLLIEYNLLKSYKDHLEVLDI
QRTDQGSYPTCMVWYPPLTKEL-----FLLICNSGYKVKLFNSTTKMCRKT----LLGPV
------YGSPIEQ--------IQILPVKTPLELQK-RYMVFINRDKVGLQILPVDGNPHK
TSALICHPSGAAGMDVSYDGRYTFTAGGQDRSVVQWEINLSALEAAVSLGGEDLTPFYGL
VSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXI
EDMFNEIRFSEYVDTGKLIDKINLPDFFKVYLNHRPPFGNTMSGIQRSFDILGFTNSKGK
KAIRREDFLKLLQTK----GEHMTEEEMSDCFATLFGLNPEGWKSEPAA-SSVKG--SEI
CFEEELPDEITAEIFTTQILGLTISQDSGQDGQ---------------------------
------------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------MSDAEEAPREATRENG
ETEMKEEE--------EPNPNYK-EVEDPQQESK-DDTLAWRESQEE---------ERKT
-GEEEGEEE-------------EEKEEEGKK-----------------DKKIVM---EET
-------E-EKAGESQEKEASGIQEET----------------------TV--E-PQEVT
ES-----M--------------IRLETQI-TDSQSV---------------------TSG
IFPK---TQ------RGSKSKLS---LQLEDAETDELLRDLSTQLEFLDLDQ----ISPE
EQQISSPE----RQ---------PS------------------------GELEEK-TDQM
PQDELGQ-ERRDLEPENREEGQERT---------------VSDIQSKA---GISRESLVS
STTEDILFQK---DKSAPVYPLTMTWSFGWNSSLPVYYIREEKQRVLLYVCAHTAIIYNV
FRNN

PF00400 // ENSGT00390000013370_0_Domain_0 (665, 704)

QYHLQGHANIISCLCVS--EDRRWIATADKGPDCLVIIW

ENSGT00390000013370_0_Linker_0_1 (704, 1036)

DSFTGIPVHT--IFDSC
PEGSG-RAMAMTHDAKYLATISDA-----EVQ-KVCIWKWTLAVETPACTLELPTEYGVQ
--NYVTFNPTNNKELVSNSKTWAIYYAWYE--------------------ERDTLAH--S
APLLTEKTFNKLVGKFSQSVFHLNLTQILSATMEGKLVVWDIHRPPSSA-----------
---------STFLGFPYIKPCKLVHLQKEGITVLTTTDSYIVTGDIKGNIKFYDHTLSIV
NWYSHLKLGAIRTLSFSKTPATPPTEKSNYP------PDCTLKGDLFVLRNFIIGTSDAA
VYHLTTDGTKLEKLF

PF00400 // ENSGT00390000013370_0_Domain_1 (1036, 1067)

VEPKDAICAISCHPYQPLIAIGSICGMIKVWNYENKQYLFSRVFE
KGLGVQSLTYNPEG-------------------------------------ALLGAGFTE
GTVYILDAMSLENESPEPFKYSRT

PF00400 // ENSGT00390000013370_0_Domain_3 (1165, 1192)

SVTHISFSHDSQYMATADR---SFTVAVYMLVVRNG
QRVWEYLARLRSHRKSIRSLLFGVYLDSNEPRLLSLGTDRLLIEYDLLRSYKDCLEVLDI
HHTDQGCYPTCMVWYPPLTREL-----FLLICNSGYKVKLFNATTKMCRKT----LLGPA
------YGSPIEQ--------TQVLPVRSMAELQK-RYLVFINRDKVGLQILPVDGNPHK
TSAIVCHPNGVAGMAVSYDGHYAFTAGGHDRSVVQWKITLSVLEAAVSLGGEDLTPFYGL
LSGGREGKFYRELEDYFYYSQLRSQGIDTMETRKVSEHICLSELPFVMRAIGFYPSEEKI
DDIFNEIKFGEYVDTGKLIDKINLPNFLKVYLNHKPPFGNTMSGIHKSFEVLGYTNSKGK
KAIRREDFLRLLVTKEKLVSNSLTSXXXXDCFASLFGLNPEGWKSEPAT-SSVKG--SEI
CLEEELPDEITAEIFATEILGLTISEYSSQDGQ---------------------------
------------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------MSDAEEAPGEATGENG
ETEMKEEE--------EPNPNYK-EVENLQQESK-DDTLAWRESQEE---------ERKM
-GEEEGEEEE-----EEKEE-EEEKEEEGKE-----------------DKKIVM---EET
-------E-EVAGEAQEKEASGIQEET----------------------TV--E-PQEVT
ES-----M--------------IHLETQI-TDSQSI---------------------TSG
IFPK---AQ------RGSKSKPS---LQLEDAETDELLQGLSTQLEFLDLDQ----ISPE
EQQISSPE----RQ---------PS------------------------GELEEK-TDWM
LQDELGR-ERRDLEPENREEGQESR---------------VSNIQSEA---GISRESLVS
STTEDILFER---DESAPVYPLTMTWSFGWNSSLPVYYIREEKQRVLLYVCAHTAIIYNV
LR

PF00400 // ENSGT00390000013370_0_Domain_0 (663, 704)

NNQHHLQGHANIISCLCVS--EDRRWIATADKGPDCLVIIWDSFTGIPVHT--IFDSC
PEGNGIRAMAMTRDAKYLATISDA-----EVQ-KVCIWKWTLAVETPACTLELPKEYGVQ
--NYLTFNPTNNKELVSNSKTQAIYYAWYE--------------------ERDTLAH--S
APLLTEKTFNKLVGKFSQSIFHLNLTQILSATMEGKLVVWDIHRPPSSA-----------
---------STFLGFPYIKPCKLVHLQK----------DYIVTGDIKGNIKFYDHTLSIV
NWYSHLKLGAIRTLSFSKTPATPPTEKSNYP------PDCTLKGDLFVVRNFIIGTSDAA
VYHLTTDGTKLEKLFVEPKDAICAISCHPYQPLIAIGSICGMIKVWNYENKQYLFSRVFE
KGLGVQSLTYNPEG-------------------------------------ALLGAGFTE
GTVYILDAMSLENESPEPFKYSRTSVTHISFSHDSQYMATADR---SFTVAVYMLLVRNG
QRVWEYLARLRSHRKSIRSLLFGVYLDSNEPRLLSLGTDRLLIEYDLLRSYKDCLEVLDI
HHTDQGCYPTCMVWYPPLTREL-----FLLICNSGYKVKLFNSTTKMCRKT----LMGPA
------YGSPIEQ--------TQVLPVRSMAELQK-RYLVFINRDKVGLQILPVDGNPHK
TSAIVCHPNGVAGMAISYDGRYAFTAGGHDRSVVQWKITLSVLEAAVSLGGEDLTPFYGL
LSGGREGKFYRELEDYFYYSQLRSQGIDTMETRKVSEYICLSELPFVMRAIGFYPSEEKI
DDIFNEIKFGEYVDTGKLIDKINLPDFLKVYLNHKPPFGNTMSGIHKSFEVLGYTNSKGK
KAIRREDFLRLLVTK----GEHMTEEEMLDCFASLLGLNPEGWKSEPAT-SSVKG--SEI
CLEEELPDEITAEIFATEILGLTISEDSGQDGQ---------------------------
------------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------MAGTPLSQHPLPCSIPVHT--IFDSC
PQGNGIRAIAISRDAKYLATISDT-----DVQ-KFCIWRWTLAVETPACTLELPKEYGFQ
--NHLAFNPANSKELVSNSKTHTIYYWWHE--------------------EKDTLVY--S
APLLTENTFNKLVGKFSQSVFHPNSSQILSATWEGKLVVWDIRRS---------------
------------ADSPSIKPCKLVHLQKEAITVLTVADGYIVTGDVKGNIKFYDQTLSIV
HWYGNLKLGCIRTLSFSQSEANPNPERRSFP------PDCTLKVVHKSVIR--VIEIFAT
VYHLTTDGTRLEKLFVEPRA

PF00400 // ENSGT00390000013370_0_Domain_1 (1041, 1067)

SVCAISCHPYQPLLAVGSTCGLIKVWDYEQKRYLFSRVFE
KGFGVQSLTYNPEGDFPPGPSQAWPAPERTWGCGSQGRVLLQAGPPGVLSGALLGAGLTE
GTVYILDAMSLQNEAPEPFKYSRSSVTHVSFSHDSQYMATADL---NFTVAVYTVVVRSG
RRLWEYLARLRSHRQSIRSLLFGVYLDSNEPRLLSLGQDRLLIEYNLSRSRRNHLEVLDV
HRTDQGHHPTCMVWYPPLTKEL-----FLLVCNSGYKVKLFNSTTKMC------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----LLFQ-G--EK-QSCHPLSLSWALGYNSSLAVHSIE---DGMLLYVCAHTVVVHDV
L

PF00400 // ENSGT00390000013370_0_Domain_0 (662, 692)

GSRQHHLQGHANAISCLCVS--EDRRWVAT

ENSGT00390000013370_0_Linker_0_1 (692, 1029)

ADQGPDPLVIIWDAFSGIPVRT--IFDSH
AGS-GVCAIAISRDAKCLVTISAG-----MVQ-RVCMWRWTYPDESPVCYVELSPEFGFQ
--DFVIFNPQNPYEFVSNSKTQVIFYLWGDA--------------------GLQ--Y--S
TPPLTKQTFGSTVGRFTQSAFHFNATQVLTGTSAGKVVVWDVERKRGLAK----------
---------EPQGRLHGMKATKLVPMQEESLTVLLVLESCIVTGDVRGQVKFYNGHLQLL
ACSDHSGTGPIQSISFSKTPSDPPGASST----SSHPFAARIYHDCPAIRNFILSTSDAT
VLRVATDG

PF00400 // ENSGT00390000013370_0_Domain_1 (1029, 1067)

TDFEKVMKEAKKAVTAIACHPQQSWLAMGSHCGLLKVW

ENSGT00390000013370_0_Linker_1_2 (1067, 1071)

DYKQ

PF00400 // ENSGT00390000013370_0_Domain_2 (1071, 1147)

LQLLVSRIFS
S-AGVQCLSYDPAG-------------------------------------SFLATGLTD
GSVHVL

ENSGT00390000013370_0_Linker_2_3 (1147, 1152)

DAISL

PF00400 // ENSGT00390000013370_0_Domain_3 (1152, 1194)

LS-CCEVFRFSRGPITHVQFSHDSEYLATADE---KYAVTVYKRVLQNE
RRCWEHLAGLHSHYKPIRSILFGIQLDGSEPRLLSLGEDRQLIEYDLSSSSKDQLVVLHR
HRVEQAAVPLCLAWYPHFSTES-----FILTANSCYKMKLYNATTKMCRKT----LLGPT
------YGSPLEK--------MQILPK-SAAEPQK-RYLAYITKDKVGLQILPVDGNPHK
SSAFICHPDGASDLAISYDGRYIFTAGGSDRTVLKWEVNLNALEAAASLGGEDLVPFYRL
LDGGQDGEFFRELEDYFYYVQLRSHGIDMLESRQVSMYIPLEEIPSVMRAMGFYPSEEEI
EEMINEVKFSEFVDTGEQVTKINLRDFIKLYINHRPAFGLSMKTIRQAFQVLGYENENGD
KVIDRGDLLSLLQCR----GEHMMEDELALCLSALLGRHPMGGRSDLDV-CDPSG--AAA
LMEEEIPEQITAERFTAGILGLSIAEPEKRTVK---------------------------
------------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MKRMADNEENALGETLGKN
-TEIDQS-T----EQTEAPPETTKE-DEP-EIV-E-TPV----------------D----
--------VAL------------E---D---------GQSAVIMEN--------------
-------ELESTIDSSKTVPEGTEENA----------------------EIT-ELSEDIT
------------------------------------------------------------
--------------------------------------VGEETIEESSKVDS----DSLN
DTQKLSPEKGDRSQTNGQPYQNDPTEEESEDLSEIENQSIRVQESLNIGEFLYEAR----
------REERKSLLPIE-----------------------K----KMESPADQSNISLVT
SSTQESLFEEK--DEKIKTYPLNLAWAFGWNSTSPIYNLHDEDQRVLLYACSHTVVIHDI
FK

PF00400 // ENSGT00390000013370_0_Domain_0 (663, 693)

NCQHHLQGHCSVISCLCVS--EDRRWIATA

ENSGT00390000013370_0_Linker_0_1 (693, 1037)

DKGPESLVIVWDSYSGIPVHT--IFDSH
PEGSGVAAIAISHDAKYLVTVGA-----ADVQ-RVCIWKWTSDTNIPVSSAELLPKFGFQ
--SYIIFNPRNNKELVSNSQIQAIFYVWEED--------------------NNKLEY--S
APCLTEKTFNKIVGKISQSIFHFNSPQLLSATMEGKLVVWDA-LSPPISS----------
---------LKPVKPHNIKAIKLIQLQTDGITVLTRVDGYVVTGDIRGHIKFYDSQLQLV
NWYSHFKLSPIKMLSFSKNPPLPPTNKSNYP------TDCSLHGQFFVVRNFIIATSDAK
VLHLTTDGTKLEKLLL

PF00400 // ENSGT00390000013370_0_Domain_1 (1037, 1067)

EPNDAIYAITCHPYQPLIAVGSLCGLLKVWNYRERKYLVSRIFE
KGI--RSLAYNSEG-------------------------------------SLIGAGFID
GTVYILDALSLENEIPEPFRYSKSAVTLTGFSHDSQYFATADA---SFSVAVYKLMVRNG
QKVWEYLARLRSHHKTIQTILFGVKLDSNEPRLLSLGNDRLLIEYDLFHSTKDCLEILSM
DRTDQGALPKYMVWYPPITKES-----FFLICNSVNKLKLFNSTTIMCRKT----LLGPA
------YGSPIEQ--------MQILPVLTTDDLQK-RYLVFINKDKVGLQILPIDGNPHK
TTAIICHPDGVTNLTLSYDGCYAFTAGGSDRSVLQWEINLNALEAAVSLGGDDLIPFYNQ
LDGGREGEFYRELEDYFYYSQLRSQGIDTMETRQMSTHIPLTELPFIMRAIGFYPSEEMI
ENMMNEIKFSNYVDTGKLVTEISLPDFIKVYINHRPAFGQTMSGIRNSFQVLGYTNKKGE
KAIKRDDFLKLLQTK----GEHMTEEELSECFATLFGLNPEGWGSEPET-FNMQV--KFI
TWIPCSPL-SP---LQ----SASLSPKTQNPGAQTPPHPGR-------------------
------------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------MSDAXXXXXXXXXXXX
XXXXXXXXX----XX------------XX-XXX-X-XXX----------------X----
--------XXX------------X---X---------XXXXXXXXX--------------
-------XXXXX-XXXXXXXXXXXXXX----------------------XXX-XXXXXXX
XX-------------------------------------------------------XXX
XX---------------------XX-X-----------XXXXXXXXXXX-------XXXX
XXXXXXXXXXXXXXXXXXXXXESQSGSESDDLSDSEDS-LGFELSLSEVPDLDQNG----
------SEEQQLSAELE---------------------KETDQMPQRKVDAVTPKESLVS
TSTEDVLFQ-K--DDSPSVFPLA--MTIGWNSTLPVFSIRDENQR-LLYVCSHTAVIYDV

PF00400 // ENSGT00390000013370_0_Domain_0 (661, 692)

FRNKQ-HLQGHANVISCLCVS--EDRRWIAT

ENSGT00390000013370_0_Linker_0_1 (692, 1029)

ADKGPDCLIIIWDSFTGXXXXX--XXXXX
XXXXXXXXX-----XXXXXXXXXXXXXXXXXX-KVCIWKWTAVD-TPACTLDLNKGYGFQ
--XXXXXXXXXXXXXXXXXXXXXXXXXXNEE--------------------KNTLVH--S
APVLTEKTFNKLVGKFSQSIFHLNLTQILSATMEGKLVVWDI-HRLPPSA----------
---------AAFVGFPCIKPCKLVQLQKQSITVLTTVDRXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------XXXXXXXXXXXXXNLIITTVDAT
VYHLTADG

PF00400 // ENSGT00390000013370_0_Domain_1 (1029, 1067)

TKLKKLFVEPKDAICAVACHPYQPLLTIGSLCGMLKVWNYETKTYLFSRIFE
KGVGVQSLTYNPEG-------------------------------------AILGAGFTE
GTVYILDAMSLENEIAEPFRYSRNSVTHISFSHDSRYMATAXX---XXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXX-----XXXXXXXXXXXXXXXXXXXXXXXX----XXXXX
------XXXXXXX--------XXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXALDAAVSLGGEDMAPFYGL
LSGGREGHFYRELEDYFYYCQLRSQGIDTMETRQVAEHISLSELPYVMRAIGFYPSEEKX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGIHHSFE-LGYTNSEGK
KAIRR-EFLRLLMTK----GEHMTQEELLDCFATLFGLNPEGWKSEPAT-TSVKG--SEM
CLEEELPDEITAEVFVTEILGLTISDHSGQDSQ---------------------------
------------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------------M
PQDELGQ-ERREEKR-----------------SSDLSE------RREA---EKPEKSLVS
-TSEDILFRK---DDRANVYPLTMTWSFGWNSSLPVYYIRDENQRVLLYVCAHTAVIYDV
FKNT

PF00400 // ENSGT00390000013370_0_Domain_0 (665, 704)

QHHLQGHANVISCLCVS--EDRRWIATADKGPDCLIIIW

ENSGT00390000013370_0_Linker_0_1 (704, 1036)

DSFTGIPVHT--IFDSC
PEGHGIEAIAITRDAKYLATISDA-----EIQ-EVCIWRWTLAVETPACTLKLLKEYGVQ
--NYLTFNPANNKELVSNSKTQAIYYLWCE--------------------EGDLLAH--S
APRLTEKTFNKLVGKFSQSVFHLNLTQILSATMEGKLVVWDIHRPTSSA-----------
---------SASAGFPQIKPCKLVHLQKEGLTVLTTVDRYIVTGDIRGNIKFYDRTLSIV
NWYSNFKLSSIRTLSFSKTPAAPPTEKSNYP------PDCTLKGDLFIVRNLIIGTSDAT
VYHLTADGTKLEKLF

PF00400 // ENSGT00390000013370_0_Domain_1 (1036, 1067)

VEPKDAICAISCHPYQPLIAIGSFCGMIKVWDYEEKKYLFSRVFE
KGLGVQSLTYNPEG-------------------------------------ALLGAGFTE
GTVYILDAMSLENQIPEPFKYSRTSVTHISFSHDSQYMATADV---YFTVAVYMVVVRNG
HRVWEYLARLRSHRKSIRSLLFGVHLDSNEPRLLSLGRDRLLIEYNLLKSCRDNLEILDI
HRTDQGNYPTCMVWYPPLTKEL-----FLLICNSGYKVKLFNSTTKMCRKT----LLGPV
------FGSPIEQ--------IQILPVKSTLELQK-RYMVFINRDKVGLQILPVDGNPHK
TAAIICHPSGVAGMALSYDGCWAFTAGGQDRSVVQWEINLRALDAAVSLGGEDLTPFYGL
VAGGREGKFYRELEDYFYYSQLRSQGIDTMETRKVSEHICLSELPFVMRAIGFYPSEEKI
DDMFNEVRFSEYVDTGKLIDKINLPDFFKVYLNHRPPFGNTMRGIQESFDILGFTNSKGK
KAIRREDFLNLLLTK----GEHMTEEEMSDCFATLFGLNPEGWKSEPVA-SSVKG--SEI
CLEEELPDEITAEIFTTDILGLTISQDFRQDPIGSEV-----------------------
------------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------MSDEGEYPLEESEEDG
ETEMEE----------EYNQYYG-EMESMQQELKEEDVLVGREPQQEGEEEE-----EEE
-GEEEGREEWEE--KEGVEE-KGEEGEEGEK--------------------E--------
----------EEERVEEEEPAVVQEET----------------------TV--K-PQEIT
KS-----M--------------TSLERLTLTDSQSV--------------------MSGT
SLVS---SNR-----TLSESKH---ALESEHSETNEPLGDLSSELRFLDLDQ----KSSE
ERE-IFPE----AH---------PS------------------------SELREK-TDQM
AQDELGR-EGP------------------GKRLSYLSEEQEKEFQSKA---QIPEKSLVS
-TSKDILFQK---DGRASVYPLTLTWSFGWNSSLPVYYIRDDNQRVLLYVCAHTAVIYNV
F

PF00400 // ENSGT00390000013370_0_Domain_0 (662, 692)

KNTQHHLQGHPNVISCLCIS--EDRRWIAT

ENSGT00390000013370_0_Linker_0_1 (692, 1029)

ADKGPNCLIIIWDSFTGIPVHT--IFDSC
PEGNGIGAIAITRDAKYLATISDA-----EIQ-KVCIWRWTLAVETPACTLSLPKEYGVQ
--NYLTFNPTNNKELVSNSKTQAIYYLWYE--------------------AGGILAH--S
APRLTEKTFNKLVGKFSQSVFHLNLTQILSATMEGKLVVWDVHRPPSSA-----------
---------SASVASPQIKPCKLVHLQKEGITVLTTVDSYIVTGDIRGNIKFYNHTLSIV
NWYSHFKLSAIRTLSFSKTPAAPPTEKSNYP------PDCTLKGDLFIVRNLIIGTADAT
VYHLTTDG

PF00400 // ENSGT00390000013370_0_Domain_1 (1029, 1067)

TKLEKLFVEPKDAICAISCHPYQPLIAIGSFCGMIKVWDYEKKKYLFSRVFK
KGLGVQSLTYNPEG-------------------------------------VLLGAGFTE
GTVYILDAMSLENQIPEPFKYSRTSVTHISFSHDSQYMATADV---HFTVAVYMVVVKNG
HRVWEYLARLRSHRKSIRSLLFGVHLDSNKPRLLSLGRDRLLIEYNLLKSYRDNLEVLDI
HRTDQGNYPTCMVWYPPLTKEL-----FLLICNSGYKVKLFNSTTKMCRKT----LLGPV
------FGSPIEQ--------IQMLPVKSTLELQK-RYMAFINRDKVGLQILPVDGNPHK
TSAIICHPSGVAGMALSYDGCYAFTAGGQDRSVVQWEINLSALEAAVSLGGEDLTPFYGL
VAGGREGKFYRELEDYFYYSQLRSQGIDTMETRKVAEHICLSELPFVMRAIGFYPSEEKI
RDMFNEIRFSEYVDTGKLIDKINLPDFFKVYLNHRPPFGNTMSGIQQSFDVLGFTNSKGK
KAIRREDLLKLLLTK----GEHMTEEEMCDCFATLFGLNPEGWKSEPAA-ASVKGLGAEI
CFEEVLPDEITAEIFTTDILGLTISQDFGQDPM---------------------------
------------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------MSDAEEAPREATGENG
ETEMKEEE--------EANPNYK-EVEDPQQESK-DDTLAWRESQEE---------ERKT
-GEEEGEEE-------------EKEEEEGKE-----------------DKKIVM---EET
-------E-EKAGEVQEKEASGIQEET----------------------TV--E-PQEVT
ES-----M--------------IRLETQI-TDSQSI---------------------TSG
IFPK---TQ------RGSKSKLS---LQLEDAETDELLRDLSTQIEFLDLDQ----ISPE
EQQISSPE----RQ---------PS------------------------GELEEK-TDRM
PQDELGQ-ERRDLEPENREEGQERR---------------VSDIQSKA---GISRESLVS
STTEDILFQK---DKSAPVYPLTMTWSFGWNSSLPVYYIREERQRVLLYVCAHTAIIYNV
FR

PF00400 // ENSGT00390000013370_0_Domain_0 (663, 704)

NNQYHLQGHANIISCLCVS--EDRRWIATADKGPDCLVIIWDSFTGIPVHT--IFDSC
PEGNGIMAMAMTHDAKYLATISDA-----EVQ-KVCIWKWTLAVETPACTLELPTEYGVQ
--NYVTFNPTNNKELVSNSKTRAIYYAWYE--------------------ERDTLAH--S
APVLTEKTFNKLVGKFSQSIFHLNLTQILSATMEGKLVVWDIHRPPSSA-----------
---------STFLGFPYIKPCKLVHLQKEGITVLTTIDSYIVTGDIKGNIKFYDHTLSIV
NWYSHLKLGAIRTLSFSKTPATPPTEKSNYP------PDCTLKGDLFVLRNFIIGTSDAA
VYHLTTDGTKLEKLFVEPKDAICAISCHPYQPLIAIGSICGMIKVWNYENKQYLFSRVFE
KGLGVQSLTYNPEG-------------------------------------ALLGAGFTE
GTVYVLDAMSLENESPEPFKYSRTSVTHISFSHDSQYMATADR---SFTVAVYMLVVRNG
QRVWEYLARLRSHRKSIRSLLFGVYLDSNEPRLLSLGTDRLLIEYDLLRSYKDHLEVLDI
HHTDQGCYPTCMVWYPPLTREL-----FLLICNSGYKVKLFNATTKMCRKT----LLGPA
------YGSPIEQ--------TQVLPVRSMAELQK-RYLVFINRDKVGLQILPVDGNPHK
TSAIV

PF00400 // ENSGT00390000013370_0_Domain_4 (1386, 1417)

CHPNGVASMAVSYDGRYAFTAGGHDRSVVQWKITLSVLEAAVSLGGEDLTPFYGL
LSGGREGKFYRELEDYFYYSQLRSQGIDTMETRKVSEHICLSELPFVMRAIGFYPSEEKI
DDIFNEIKFGEYVDTGKLIDKINLPDFLKVYLNHKPPFGNTMSGIHKSFEVLGYTNSKGK
KAIQREDFLRLLVTKGEH----MTEEEMLDCFASLFGLNPEGWKSEPAT-SSVKG--SEI
CLEEELPDEITAEIFATEILGLTISEDSGQDGQ---------------------------
------------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------MGGGSQEE---------EEER
-D--------------EEEE-DG---EEGEEKV--GEGEEGEEEE---EEEEEE----EE
-------E-MEKEEESEEETEGMQKKT----------------------SV--K-YRDFK
LK---------------------------KT-ASDS---------------------LSG
SSLR---SP------KGSKTKDS---FQSGSSMPDELSRGPSLQYELLDLEP----GSSE
EQQVGLHE----RQ---------SA------------------------GELEEW-TDQA
PHSGAGPKT---------AEEPIQGEKRRDKRVSYSLYEEVKEFPCRV---AVSKQSQVS
TSTEDGLFQKVP---APEVQPLTVTWTFGWNSSLPVFYIREERHRVLLYVCAHTVVIYNT
F

PF00400 // ENSGT00390000013370_0_Domain_0 (662, 704)

WNRQHHLQGHPNVISCLCVS--EDRRWIATADKGPGCLIIIW

ENSGT00390000013370_0_Linker_0_1 (704, 1040)

DSFTGIPVHT--IFDSC
PDGSGIRAIAITRDAKYLATISDA-----EIQ-KVCIWKWTLAVETPACTLELPTEYGFQ
--NYLTFNPTNNKELVSNSKTQAIYYSWDE--------------------EKDTLVH--S
APLLTEKTFNKLVGKFSQSVFHLHLTQILSATMEGKLVVWDVQRL---------------
------------GGSPCIKPCKLVHLQREGITVLTTVDSYIVTGDIRGNIKFYDHTLSIV
NWYSHFKLSAIRTLSFSKTPAAPPTEKSNYP------PDCTLKGDFFVVRNFIIGTSDAT
VYHLTTDGTKLEKLFVEAK

PF00400 // ENSGT00390000013370_0_Domain_1 (1040, 1067)

DAICAISCHPYQPLIAIGSVCGMIKVWDYEKKKYLFSRVFE
KGLGVQSLSYNPEG-------------------------------------ALLGAGFTE
GTVYILDAMSLENESRKPFKYSR

PF00400 // ENSGT00390000013370_0_Domain_3 (1164, 1192)

SNVTHISFSHDSQYMATADV---NFTVAVYMVVVKNG
QRVWEYLARLRSHRKSIRSLLFGVHLDSNDPRLLSLGRDRLLIEYNLRKSCKDHLEVLDI
QRTDQGSYPTCMVWYPPLTKEL-----FLLVCNSGYKVKLFNSTTKMCRKT----LLGPT
------FGSPIEQ--------TQVLPARTAKELQK-RYLVFINKDKVGLQILPVDGNPHK
TWAIVCHPDGVASMALSCDGSYAFTAGGHDRSVVQWKINLSALEAAVSLGGEDLTPFYGL
VPGGREGKFYTELEDYFYYSQLRSQGIDTMEGRQVSEHICLSELPFVMRAIGFYPSEEKI
ADMFNEVKFS------------------------EPPFGNTMSGIQQTFEVLGFTNSRGQ
KAIRREDFLKLLQTK----GEHMTQEEMSNCFATLFGLNPEGWGSEPAA-TSVKG--SEI
CLEEELPEEITAEIFTTEILGLAISEDSEQSGQ---------------------------
------------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------MSDAEEAPREATGENG
ETEMKEEE--------EPNPNYK-EVEDPQQESK-DDTLAWRESQEE---------ERKT
-GEEEEEEE-------------EKEEEEGKE-----------------DKKIVM---EET
-------E-EKAGEVQEKEASGIQEET----------------------TV--E-PQEVT
ES-----M--------------IHLETQI-TDSQSI---------------------TSG
IFPK---TQ------RGSKSKLS---LQLEDAETDELLRDLSTQIEFLDLDQ----ISPE
EQQISSPE----RQ---------PS------------------------GELEEK-TDWM
PQDELGQ-ERRDLEPENREEGQERR---------------VSDIQSKA---GISRESLVS
STTEDILFQK---DKSAPVYPLTMTWSFGWNSSLPVYYIREERQRVLLYVCAHTAIIYNV
FR

PF00400 // ENSGT00390000013370_0_Domain_0 (663, 704)

NNQYHLQGHANIISCLCVS--EDRRWITTADKGPDCLVIIWDSFTGIPVHT--IFDSC
PEGNGIRAMAMTHDAKYLATISDA-----EVQ-KVCIWKWTLAVDTPACTLELPTEYGVQ
--NYVTFNPTNNKELVSNSKTRAIYYAWVI--------------------TI--------
-TFLLKQTFNKLVGKFSQSIFHLNLTQILSATMEGKLVVWDIHRPPSSA-----------
---------STFLGFPYIKPCKLVHLQKEGITVLTTIDSYIVTGDIKGNIKFYDHTLSIV
NWYSHLKLGAIRTLSFSKTPATPPTEKSNYP------PDCTLKGDLFVLRNFIIGTSDAA
VYHLTTDGTKLEKLFVEPKDAICAISCHPYQPLIAIGSICGMIKVWNYENKQYLFSRVFE
KGLGVQSLTYNPEG-------------------------------------ALLGAGFTE
GTVYILDAMSLENESPEPFKYSRTSVTHISFSHDSQYMATADR---SFTVAVYMLVVRNG
QRVWEYLARLRSHRKSIRSLLFGVYLDSNEPRLLSLGTDRLLIEYDLLRSYKDHLEVLDI
HHTDQGCYPTCMVWYPPLTREL-----FLLICNSGYKVKLFNATTKMCRKT----LLGPA
------YGSPIEQ--------TQVLPVRSMAELQK-RYLVFINRDKVGLQILPVDGNPHK
TSAIVCHPNGVAGMAVSYDGRYAFTVGGHDRSVVQWKITLSVLEAAVSLGGEDLTPFYGL
LSGGREGKFYRELEDYFYYSQLRSQGIDTMETRKVSEHICLSELPFVMRAIGFYPSEEKI
DDIFNEIKFGEYVDTGKLIDKINLPDFLKVYLNHKPPFGNTMSGIHKSFEVLGYTNSKGK
KAIRREDFLRLLVTKGEH----MTEEEMLDCFASLFGLNPEGWKSEPAT-ASVKG--SEI
CLEEELPDEITAEIFATEILGLTISEDSGQDGQ---------------------------
------------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------MSDAEEAPRESTGKNG
ETEIEEEE--------EPNLNYK-EVENPQEEVK-DDTLAWRESQEEE---------KKK
-GEEEE-EEGE---------------EEG------------E-----EDKEIVM---EET
-------E-EKAGDAQEEEASGIQKET----------------------AV--E-PQEMK
RS-----M--------------TSLETRI-TDSQSA---------------------TSG
IFPT---TQ------RGSESKPS---LRSEDSEAD--------ELEFLDLDQ----ISPE
EQQMSSPD----RQ---------PS------------------------GELEEN-TDQR
PQDELGR-ERRDLEPEKREEGQERS---------------ASSIQSIA---GISRESLVS
TTTEDILFQK---DKNAPVYPLTLTWSFGWNSSLPVYYIREEKQRVLLYVCAHTAIIYNV
FR

PF00400 // ENSGT00390000013370_0_Domain_0 (663, 704)

NHQYHLQGHANIISCICIS--EDRRWIATADKGPDCLVIIWDSFTGIPVHT--IFDSC
PEGNGIRAMAMAHDAKYLATISDA-----KVQ-KVCIWKWTLAAETPACTLELPKEYGLQ
--NYLTFNPTNNKELVSNSKTQAIYYAWYE--------------------ERDTLAH--S
APLLTEKTFNKLVGKFSQSIFHLNLTQMLSATMEGKLVVWNIHRPPSSA-----------
---------STFLGFPYIKPCKLVHLQKESITVLTTIDSYIVTGDIKGNIKFYDHTLTIV
NWYSHLQPSAVRTLSFSKTPATPPTEKSNYP------PDCTLKGDPFVVRNFIIGTSDAT
VYHLTTDGTKLEKLFVEPKDAICAISCHPYQPLIAIGSICGMIKVWNYEKKRYLFSRVFE
KGLGVQSLTYNPEG-------------------------------------TLLGAGFTE
GTVCILDAMSLENESPEPFRYSRTSVTHISFSHDSQYMATADI---SFTVAVYMMVVRNG
QRVWEYLARLRSHRKSIRSLQFGVYLDSNEPRLLSLGTDRLLIEYDLLRSYKDHLEVLDI
HRTDQGCYPTCMVWYPPLTREL-----FLLICNSGYKVKLFNATTKMCRKT----LMGPA
------YGSPIEQ--------AQVLPVRSMAELPK-RYLVFINRDKVGLQILPVDGNPHK
TTAIVCHPNGVAGMALSYDGLYAFTAGGHDRSVVQWKINLSVLEAAVSLGGEDLTPFYGL
LSGGREGKFYRELEDYFYYSQLRSQGIDTMETRKVSEHICLSELPFVMRAIGFYPSEEKI
DDIFNEIRFGEYVDTGKLIDKINLPDFLRVYLNHRPPFGNTLSGIHKSFEVLGYTNSKGE
KAIRREDFLRLLVTK----GEHMTEEEMLDCFASLFGLNPEGWKSEPAA-SSVKG--SEI
CLEEELPDEITAEIFATEILGLTISEDSGQDGKGARCHS-RTRSAQHTPQTRFCPRETSI
SETTFRIHLKWLSLKAHSAAEKQNDNHVVTHTRRPLHYVGSSWKSGTKDSCAFHTGPVAG

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------YLQNLSWSFGLNNKIPVFNFYDEERQVIVYACAHTAVIHDI
SQNRQHHLQGHCSCISCMCVS--EERRWIATADQGTESLIIIWDSFSGIPVHT--IFNSH
PEG-GVIAMSFSHNGKYLATVGGG-----TKQ-RVCIWEWTTDTGKPICSAELRQEFGIQ
--TYIVFNAQDQTQLVTSSETQVIFYTWFET--------------------HNSLDY--E
APPLNDNTFNKVVGEFSQSVFDFSATRALTGTSAGKLVVWETIHSPSIKA----------
---------TSSIQPHKKKALKLMHLQKDAITVLSTHDRYFVTGDVQGHVKFYDQRLQLV
NWYSHLTLRPVRSISFSTCPPVTASGRTRYP------QDCSIKGDQFAISNFIVSTVDSV
VLHVHTDG

PF00400 // ENSGT00390000013370_0_Domain_1 (1029, 1067)

TVLKEHMHEPSEAVHALACHPCEHLIAIGSYSGLLKVWNYKARKLFISRIFG
KGKSLHCLSYDPKG-------------------------------------FLLGAGFTD
GSVYILDAMTLEDEIAEPFKYAR

PF00400 // ENSGT00390000013370_0_Domain_3 (1164, 1194)

GSITHIAFSHDSQYLATADT---EFTVTLF

ENSGT00390000013370_0_Linker_3_4 (1194, 1378)

KLSREKN
GVTWQYFGRYRSHYKKIQSLVFGIHLDTNEPRLISLGMDRMLVEYDLANCVKGYLQIKST
DRIEQSAVPQSLAWYPPVTKEC-----FILVANDHYKMKLYNATTKMCRKT----LLGPT
------FGSPVRR--------MEVLPTYS-EEICK-GYMTYITDDKVGLQILPLDGN

PF00400 // ENSGT00390000013370_0_Domain_4 (1378, 1417)

PHK
SMSLICHPDGVSNLACSYDGCFVFTAGGDDCTVLMWKTNLQALESVSSLGGDGLTPFYGL
LQGGREGLLFKELENYFYYAQLRHQGIDTMETRQVSTHIPLKEVPFIMRALGYYPSEQEV
ENMLNEVKFSEYVDTGKQVTCISLEELIKLYINHRPAFGLFMEEIQWAFQVLGFTNGDGK
QTINRGDFLQILQSR----GKGCTKHRVRFFFCSFMLLNKIQHKMIF-----SAG--AAD
LLEQGIPEEITTDMFAADILGLPFQVNGNYEEH---------------------------
------------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------MSDAEEAPGEATGENG
ETEMKAEE--------EPNPNYK-EVENLQQESK-DDTLAWRESQEE---------ERKM
-GEEEEE--------EEKEE-EEEKEEEGKE-----------------DKKIVM---EET
-------E-EVAGEAQEKEASGIQEET----------------------TV--E-PQEVT
ES-----M--------------IRLETQI-TDSQSI---------------------TSG
IFPK---AQ------RGSKSKPS---LQLEDAETDELLRGLSTQLEFLDLDQ----ISPE
EQQISSPE----RQ---------PS------------------------GELEEK-TDWM
LQDELGR-ERRDLKPENREEGQESR---------------VSNIQSEA---GISRESLVS
STTEDILFER---DESAPVYPLTMTWSFGWNSSLPVYYIREEKQRVLLYVCAHTAIIYNV
LR

PF00400 // ENSGT00390000013370_0_Domain_0 (663, 704)

NNQHHLQGHANIISCLCVS--EDRRWIATADKGPDCLVIIWDSFTGIPVHT--IFDSC
PEGNGIRAMAMTHDAKYLATISDA-----EVQ-KVCIWKWTLAVETPACTLELPKEYGVQ
--NYLTFNPTNNKELVSNSKTQAIYYAWYE--------------------ERDTLVH--S
-------TFNKLVGKFSQSIFHLNLTQILSATMEGKLVVWDIHRPPSSA-----------
---------STFLGFPYIKPCKLVHLQKEGITVLTTIDSYIVTGDIKGNIKFYDHTLSIV
NWYSHLKLGAIRTLSFSKTPATPPTEKSNYP------PDCTLKGDLFVVRNFIIGTSDAA
VYHLTTDGTKLEKLFVEPKDAICAISCHPYQPLIAIGSICGMIKVWNYENKQYLFSRVFE
KGLGVQSLTYNPEG-------------------------------------ALLGAGFTE
GTVYILDAMSLENESPEPFKYSRTSVTHISFSHDSQYMATADR---SFTVAVYMLVVRNG
QRVWEYLARLRSHRKSIRSLLFGVYLDSNEPRLLSLGTDRLLIEYDLLRSYKDCLEVLDI
HHTDQGCYPTCMVWYPPLTREL-----FLLICNSGYKVKLFNSTTKMCRKT----LMGPA
------YGSPIEQ--------TQVLPVRSMAELQK-RYLVFINRDKVGLQILPVDGNPHK
TSAIVCHPNGVAGMAISYDGRYAFTAGGHDHSVVQWKITLSVLEAAVSLGGEDLTPFYGL
LSGGREGKFYRELEDYFYYSQLRSQGIDTMETRKVSEYICLSELPFVMRAIGFYPSEEKI
DDIFNEIKFGEYVDTGKLIDKINLPDFLKVYLNHKPPFGNTMSGIHKSFEVLGYTNSKGK
KAIRREDFLRLLVTK----GEHMTEEEMLDCFASLFGLNPEGWKSEPAT-SSVKG--SEI
CLEEELPDEITAEIFATEILGLTISEDSGQDGQ---------------------------
------------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------MSDAEEAPGEATGENG
ETEMKAEE--------EPNPNYK-EVENLQQESK-DDTLAWRESQEE---------ERKM
-GEEGGEEEEE----EEKEE-EEEKEEEGKE-----------------DKKIVM---EET
-------E-EVAGEAQEKEASGIQEET----------------------TV--E-PQEVT
ES-----M--------------IRLETQI-TDSQSI---------------------TSG
IFPK---AQ------RGSKSKPS---LQLEDAETDELLRGLSTQLEFLDLDQ----ISPE
EQQISSPE----RQ---------PS------------------------GELEEK-TDWM
LQDELGR-ERRDLEPENREEGQESR---------------VSNIQSEA---GISRESLVS
STTEDILFER---DESAPVYPLTMTWSFGWNSSLPVYYIREEKQRVLLYVCAHTAIIYNV
LR

PF00400 // ENSGT00390000013370_0_Domain_0 (663, 704)

NNQHHLQGHANIISCLCVS--EDRRWIATADKGPDCLVIIWDSFTGIPVHT--IFDSC
PEGNGIRAMAMTHDAKYLATISDA-----EVQ-KVCIWKWTLAVETPACTLELPKEYGVQ
--NYLTFNPTNNKELVSNSKTQAIYYAWYE--------------------ERDTLAH--S
APLLTEKTFNKLVGKFSQSIFHLNLTQILSATMEGKLVVWDIHRPPSSA-----------
---------STFLGFPYIKPCKLVHLQKEGITVLTTIDSYIVTGDIKGNIKFYDHTLSIV
NWYSHLKLGAIRTLSFSKTPATPPTEKSNYP------PDCTLKGDLFVVRNFIIGTSDAA
VYHLTTDGTKLEKLFVEPKDAICAISCHPYQPLIAIGSICGMIKVWNYENKQYLFSRVFE
KGLGVQSLTYNPEG-------------------------------------ALLGAGFTE
GTVYILDAMSLENESPEPFKYSRTSVTHISFSHDSQYMATADR---SFTVAVYMLVVRNG
QRVWEYLARLRSHRKSIRSLLFGVYLDSNEPRLLSLGADRLLIEYDLLRSYKDCLEVLDI
HHTDQGCYPTCMVWYPPLTREL-----FLLICNSGYKVKLFNSTTKMCRR-----LWGPA
------YGSPIEQ--------TKSSQ---------------WKHGRVGLQILPVDGNPHK
TSAIVCHPNGVAGMAISYDGRYAFTAGGHDRSVVQWKITLSVLEAAVSLGGEDLTPFYGL
LSGGREGKFYRELEDYFYYSQLRSQGIDTMETRKVSEYICLSELPFVMRAIGFYPSEEEI
DDIFNEIKFGEYVDTGKLIDKINLPDFLKVYLNHKPPFGNTMSGIHKSFEVLGYTNSKGK
KAIRREDFLRLLVTK----GEHMTEEEMLDCFASLFGLNPEGWKSEPAT-SSVKG--SEI
CLEEELPDEITAEIFATEILGLTISEDSGQDGQ---------------------------
------------------------------------------------------------