Query Results 

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------------------------------------------MHVFIDEN-GEIRSCYLK
AGCQKEGNFRHQISNCDCISNAHEIQFSSSSTTTSESQDPSSGDQAASALQQQLLLMVAR
RTLSETPR-----------QPSQDPEDSSCSSAQRKLNR-QFYRFIIFPGKWIKIWYDRL
TLLALLD---RTEDIKENVLAVILVVLVSLLGFMTLNQGFCKDIWVLLFCLVMASCQYSL
LK-----------SVQPDPASPIHGHNKIITYSRPVYFCILCGLILLLDAGSKDTNPSVY
TMYGLKLFSPRFLQSARDHVIVFLYCFPAISLLGLFPQINTFCIYLLEQIDMLLFGGSAA
AGLVSAL--YSISRSFVVLIVLYAFCFSAVK-EPWDAQHIPALFSAFCG-LLVALSYHLS
RQSSDPSVL-MSLIQCKYVPHFLRQQF---EDSSADPLPEKMR--------ESVKEILKS
DLIVCTAAAVLSFAVSASTVFLSLRPFLSIVLFALAWTVGFVT-HYILPQLRKHHPWLWI
SHPILKSKEHRQREVRDAAHLMWFERLYVWLQCFEKYILYPAIILNALTIDAFSISKYKK
LGTHCDIILITV--AGMKLLRSSFCNPI--NQFVTLSFTVIFFRFDYRDISENFLLDFFM
MSIVFHK--LWDLLQKLQFIMTYIAPWQIAWGSSFHVFAQLFAIPH-------NSAMLFF
QTLATSVFSTPLSPFLGSVIFIASYARPIKFWEKNYNTK---RSDHSNTRLAIQIEKDAG
ND-DNNLNSIFYEHLTRSLQESLCGDLILGRWGNYSTGDCFILASDYLNAFVHLIEIGNG
LVTFQLRGLEFR-GTYCQQREVEAITEGDEDNEGCCCCKPGHLPHLLSCNAAFNLRWLTW
EITRTQYILEGYSIIDNNAATMLQVFDLRRILIRYYIKSIIYFTASSPKIFDWIKDESIQ
KILQPYAKWHYIERDLAMFNINIDEDYVPCLQGITRASFCSVYLDWIQYCARKRVEHATL

PF05041 // ENSGT00390000013164_1_Domain_0 (1861, 2098)

KTLHLDSDEDSPLVTLSFALCILGRRALGTAAHNMAISLDSFLYGLHALFKGDFRIAAKD
EWVFADMDLLHKVVAPAIR-----MSLKLHQDQFTCPDEYEDPAVLYEAIQSFEE-KVVI
CHEGDPAWRSAVLSNREELLTLRHVVDEGADEYKVIMLHKSYLSFKVIKVNKECVRGLWA
GQQQELIFLRNRNPERGSIQNNKQVLRNLINSSCDQPLGYPMYVSPLTTSYLGTHSQLRN
IWGGPVSLDNIKKWFRSKWLRMRKDCHA-AHHDRGNVEEVDNGGGSSS-G------HSAG
NSSQSSSSQHTRDGTPQLQAS-SHEVHQRAG----RRKHRSQSVQAHTALSQRPPVSSHS
GPIVESRQPFIQTSTSAHEIAQRLSSSQLSLHNSATSVFSQSPAVPVAGQ-LTVQDRAAA
LLRSSLASSTSSTLSLLFGKRSFSSALVISGLSAADGGNTSDTQSSSSMNIAMGPSARAA
SQATRQLTE-TCDATEAT-ESRPRREQGPAHAIFM-SQTLECRR-ASQEDMALEDTASQQ
SLSEEQ

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-------------------------MVSQVLQLLR-------QGVWP-------------
KFTNSC--H-------LYLWLFLL-------LLP--------LALHLAFPPNAI----IV
FFYCSAVTIFFTIIKLVSYRLHLMFDKGELIQQKPSRKEEKPNKDKEAK--GEHITNHKN
PS--NNRQIHNGKKEEASRNLSTPPLRCSSRGQSITSHHSSG-PLELSAQETVEDLKGVI
LLEDHPIAP-VSSTSPGIKVESLPASQAHMLETTPKSVIPVKPVATETLINGKGKERGG-
KGQ-PPLRHRSEGG-LVDKGPLKKLPHLSLSQYDLLETDVSFQPWGSENSVLI-PEPVSC
PQGSIRERVQSKSPQDSLSSS-CPQCDTIVAKPV-EEPADTSCQVD--------------
----TSCQVDLPLHQEVDSSDSEVAVTLIDTSQPGDPLSLHEPIKIVITMSSTPNS-MTD
LESSLHLRVVGTEKTSVKSDAEPTNPGAAGSPHA-EQISIPVITLDLPEGGG--GGVPCP
EGNRSERTPERLK-TRVSTNQCSG--YGSGEGGNAIKDHSSSS-REPWESVSRLTPDIAS
E-------SKVGKEGQTNLDPSSCKSSHEKRHARVLSVDSGTDV-LSKSSAEIVND-TEK
TMPTSKSDLEAKEGQMPNESNFLEFVSLLESINTSKMTASNQLNGSAEQNEESGLLR---
-------DNCSQEKKEEILENEKPSGHS-----SKQGKPDLQSQDHTSTGPACTQPAKTT
AFFQGNRQRQIIYRVTSQQDSSVLQVISGPETSVQEEISVDAMHVFIDEH-GEIRSCYLK
SGNQKEGPLQPLPSNSDCLSQAREMQVSSSSTTTSESQDPSSGDPAVSALQQQLLLMVAR
RTQSETPRH-----------VSQDLEASSCSSTQGKFNREQFYKFIIFPGKWIKVWYDRL
TLLALLD---RTEDIKENVLAILLIVLVSLLGFLTLSQGFCKDMWVLLFCLVMASCQYSL
LK-----------SVQPDPASPIHGHNQIITYSRPIYFCVLCGLILLLDTGAKARHPPSY
VVYGLKLFSPVFLQSARDYLIVFLYCFPAISLLGLFPQINTFCTYLLEQIDMLFFGGSAV
SGITSAV--YSVARSVLAAALLHAVCFSAVK-EPWSMQHIPALFSAFCG-LLVALSYHLS
RQSSDPSVL-MSFIQCRLFPKFLHQNL---EESAADPLPKKMK--------DSVTDVLKW
DLIVCAVVAVLSFAVSASTVFLSLRPFLSIVLFALAGAVGFVT-HYVLPQLRKHHPWMWI
SHPILKNKEYHQQEVRDVAHLMWFEKLYVWLQCFEKYILYPALILNALTIDAFLISNHRR
LGTHWDIFLMIIA--GMKLLRTSFCNPV--YQFINLSFTVIFFHFDYKDISESFLLDFFM
VSILFSK--LGDLLHKLQFVLTYVAPWQMAWGSSFHVFAQLFAIPH--------SAMLFF
QTIATSIFSTPLSPFLGSVIFITSYVRPVKFWEKNYNTR---RVDNSNTRLAVQIERDPG
ND-DNNLNSIFYEHLTRTLQESLCGDLVLGRWGNYSSGDCFILASDDLNAFVHLIEIGNG
LVTFQLRGLEFR-GTYCQQREVEAIMEGDEEDRGCCCCKPGHLPHLLSCNAAFHLRWLTW
EITQTQYILEGYSILDNNAATMLQVFDLRRILIRYYIKSIIYYMVTSPKLLSWIKNESLL
KSLQPFAKWHYIERDLAMFNINIDDDYVPCLQGITRASFCNVYLEWIQHCARKRQEPST-
T---L

PF05041 // ENSGT00390000013164_1_Domain_0 (1866, 2097)

DSDEDSPLVTLSFALCTLGRRALGTAAHNMAISLDSFLYGLHALFKGDFRITARD
EWVFADMDLLHKVVAPAIR-----MSLKLHQDQFTCPDEYEDPAVLYEAIQSFEK-KVVI
CHEGDPAWRGAVLSNKEELLTLRHVVDEGADEYKVIMLHRSFLSFKVIKVNKECVRGLWA
GQQQELIFLRNRNPERGSIQNNKQVLRNLINSSCDQPLGYPMYVSPLTTSYLGTHRQLKN
VWGGPITLDRIRTWFWTKWVRMRKDCNARQ-HSGGNIEDV-DGGGAP---TTGGNNAPSG
GSQESSAEQPRKGGAQHGVSSC--EGTQRTG----RRKGRSQSVQAHSALSQRPPMLSSS
GPILESRQTFLQTSTSVHELAQRLSGSRLSLHASATSLHSQPPPVTTTGH-LSVRERAEA
LIRSSLGSSTSSTLSFLFGKRSFSSALVISGLSAAEGGNTSDTQSSSSVNIVMGPSARAA
SQATRHLSE-PCEPPDAT-EQGQLHDRRLAEAMAD-TLGVVCRR-ASQEDMGLDDTASQQ
SVSDEQ

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-------------------------MVSQVLQLLR-------QGVWAALTGGWYHDPEQS
KFTNSC--H-------LYLWLFLL-------LLP--------LTLHLAFPPNAI----TI
FIYCSSVTIFFTVIKLVSYRLHLMFDEGEVIQQRSSLSTERQNKEKEAK--SENVIHHKS
PS--NNRQTNNGKVEEVNRNLSTPPLHCSSRGHSINSHYSSG-LLELPAQETVEDLKGVI
LSEDQPIAP-VSSTSPCIKTESLTVSPANMSDTTTTAAKLMKPVAMETVINNEIRGKGD-
KVQ-PPSHHRSEDV-LVGKEVMKKLPHLSLSQCDVLGTGIAFQPWGSENSVLI-TEPFSH
SKGSKREQLQSKSPQDSLSSS-CPQCNTVISKQAEEEQVN--------------------
----SSCQADQSLNEGIDCSDSEVAITLVDSSLPGDPLSLHEPIKIVITMSSTPNS-MTD
LESSLHLKVIGTEKNGANPDAHPPVVDVTHPYNN-EQIRIPVITFELSEDGG--G-NACS
DISEREKTPERLM-VDISSNPCSG--YESGELDNAAKGCNDAA-NGDSETTPLVASNLTC
K-------MEVDKEGQDSLDPSSCKTAHEKRHARVLSVDSGTDVLLSKSSTELPND-KEK
TLPTSKSDLEAKEGQLPNESSFLEFVSLLESINTSKVMTSNPSSVTTELIKEKGIIG---
-------DHHPLEKKEEIIESEKPSEHI-----SKQGKGDVQSQDHTSASPALTEPTKIT
TLFQGNRQRQIIYRVTSQQDSSVLQVISGPETSLQDEIPVDAMHVFIDEH-GEIRSCYLK
SGNQKEGELLRQPSNCDCVSNVRERHFSSSSTTTSASQEPSSGEPALSALQQQLLLMMAR
RTQSETPRVHCNITAPNISHLSQDLEESSCSSAPKKFNRDQFYKFIIFPGKWIKVWYDRL
TLLALLD---RTEDIKENIFAVFLIILVSLLGFLTLNQGFCKDVWLLLFCLVMASCQYSL
LK-----------SVQPDPASPIHGHNQIITYSRPIYFCVLCGLILLFDIAAKARNPPSY
TVYGLRFFSSGSLQSARDQLIVLLYCFPAISLLGLFPQINTFCIYLLEQIDMLVFGGSAA
AGTLSAI--YSISRSFVVAVVLYAFCFSAVK-EPWNTQHIPALFSAFCG-LLVAVSYHLS
RQSSDPSVL-LSFIQCKLFPHFFHRNL---EEMPSDPLPKKMR--------DSVKEILKS
DLIVCTVVAILSFAVSASTVFLSLRPFLGLILFALACAVGFVT-HYVLPQLRKHHPWMWI
SHPILKNKEYYQREVKDVAHLMWFERLYVWLQCLEKYILYPAIILNALTIDAFSISNYRR
LGGHCDIFLITI--AGMKLLRTSFCNPV--HHFVTLSFTVIFFQFDCKNLSESFLLDFFM
VSILFSK--LGDLLHKLQFVMTYVAPWQLAWGSSFHVFAQLFAIPHSA--------MLFF
QTIATSIFSTPLSPFLGSVIFITSYARPVKFWEKNYNTR---RVDNSNTRLAVQIEKDPG
ND-DNNLNSIFYEHLTRSLQVSLCGDLVLGRWGNYSSGDCFILASDYLNAFVHLIEIGNG
LVTFQLRGLEFR-GTYCQQREVEAIMEGDEDDRSCCCCKPGHLPHLLSCNAAFNLRWLTW
EITRTQYILEGYNIIDNNAATMLQVFDLRRILIRYYIKSIIYFTVSSPKLQAWIKNESIL
KSLQPFAKWHYIERDLAMFSINIDDDYVPCLQGITRASYCNVYLEWIQYCARKRRER---
----

PF05041 // ENSGT00390000013164_1_Domain_0 (1865, 2097)

LDSDEDSPLVTLSFALCIMGRRALGTASHNMAFSLDSFLYGLHALFKGDFRITSRD
EWVFADMDLLHKVVAPAIR-----MSLKLHQDQFTCLDEYEDPVVLYEAIQSFEK-KVVI
CHEGDPAWRSAVLSNKEELLTLRHVVDEGSDEYKVIMLHKSYLSFKVIKVNKECVRGLWA
GQQQELIFLRNRNPERGSIQNNKQVLRNLINSSCDQPLGYPMYVSPLTTSYLGTHSQMRN
VWGGPISLDNIKSWFLTKWLRMRKDCNAS-QHSGGNIEDVDSGGGTSAGSS----SGSSS
SSQENSVEQPRKEISQFRFSS--QGGTYRPG----RRKGRSQSAQAHATFIQRPPISSLS
GPALESHPSLFQTSTSVHEIAQRLSSSQLSLHNSTTSLHSQPRPISTTGH-LNVRERAEA
LIRSSLGSSTSSTLSFLFGKRSFSSALVISGLSAADGGNTSDTLSSSSVNIAMGPSARAM
SQTT-RFSE-PCEMTYAT-EQGRLRDQHLPQAMAE-SLSVICRR-ASQEDMGLDDTASQQ
SLSEE-

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-------------------------MVSQVLQLLR-------QGVWAALTGGWYHDPEQS
KFTNSC--H-------LYLWLFLL-------LLP--------LALHLAFPPNAI----LV
FFYCSSVTIFFTIIKLVSYRLHLMFDKGEVIQQKPSRKEEKPSTDKEAK--GEHITNHKN
PS--NNRQIHNGKKEEANRNLSTPPLRCSSRGQSITSHRSSG-PLELSAQETVEDLKGVI
LSEDHPIAP-VSSTSPGIKMESLPASQAHMLETTPKSAIPVKPVTTETFISGKGKERGS-
KGQ-PPLRHRSEGG-LVDKGPLKKLPHLSLSQYDLLETDVSFQPWGSENSVLI-PEPVSC
PQGSIRERVQSTSPQDSLSSS-CPQCDTIVAKPV-EEPVDTSCQVDTSCQVDTSCQADTS
CQADTSCQVDLPLNQEVDSSDGEVAVTLIDTSQPGDPLSLHEPIKIVITMSSTPNS-VTD
LESSLHLKVVGTEKTGLKSGAEPTNQRAASSPNA-EQISIPVITLDLPEDGG--GGIPCP
EGNGSKRTPERLK-ARISTNQCSG--YRSGEGESATKDHSSSS-REPWESASWLTPDIAS
E-------SKVGKEGQINLDPSSCKSSNEKRHARVLSVDSGTDVFLSKSSAEIIND-KEK
TMPTSKSDLEAKEGQIPNESNFLEFVSLLESINTSKVAASNQLNGSAEPNEESGLLR---
-------DKCSQEKKEEILENEKPSGHN-----SKQGKPDLQNQDHTSTSPVCTQPAKTT
AFFQGNRQRQIIYRVTSQQDSSVLQVISGPETSVQEEISVDAMHVFIDEH-GEIRSCYLK
SGNQKEGPLQPLPSNYDCLSQAREMQVSSSSTTTSESQDPSSGDPAVSALQQQLLLMVAR
RTQSETPRH-----------VSQDLEDSSCSSTQGKFNREQFYKFIIFPGKWIKVWYDRL
TLLALLD---RTEDVKENVLAILLIVLVSLLGFLTLSQGFCKDMWVLLFCLVMASCQYSL
LK-----------SVQPDPASPIHGHNQIITYSRPIYFCVLCGLILLLDTGAKARHPPSY
VVYGLKLFSPVFLQSARDYLIVFLYCFPAISLLGLFPQINTFCIYLLEQVDMLFFGGSAV
SGITSAV--YSVARSILAAALLHPVCFSAVK-EPWSMQHIPALFSAFCG-LLVALSYHLS
RQSSDPSVL-MSFMQCRLFPKFLHQNL---EESSADPLPKKMK--------DSVTDVLKW
DLIVCAVVAVLSFAVSASTVFLSLRPFLSIVLFALAGAVGFVT-HYLLPQLRKHHPWMWI
SHPILKNKEYHQRELRDVAHLMWFERLYVWLQCFEKYILYPALILNALTIDAFSISNHRR
LGTHWDIFLMITA--GMKLLRTSFCNPG--YQFINLSFTVIFFHFDYKDISESFLLDFFM
VSILFSK--LGDLLHKLQFVLTYVAPWQMAWGSSFHVFAQLFAIPH--------SAMLFF
QTIATSIFSTPLSPFLGSVIFITSYVRPVKFWEKNYNTR---RVDNSNTRLAVQIERDPG
ND-DNNLNSIFYEHLTRTLQESLCGDLVLGRWGNYSSGDCFILASDDLNAFVHLIEIGNG
LVTFQLRGLEFR-GTYCQQREVEAIMEGDEEDRGCCCCKPGHLPHLLSCNAAFHLRWLTW
EITRTQYILEGYSILDNNAATMLQVFDLRRILIRYYIKSIIYYMVTSPKLLSWIKNESLL
KSLQPFAKWHYIERDLAIFNINTDDDYVPCLQGITRASFCNVYLEWIQHCARKRQEPSK-
T---L

PF05041 // ENSGT00390000013164_1_Domain_0 (1866, 2097)

DSDEDSPLVTLSFALCTLGRRALGTATHNMAISLDSFLYGLHALFKGDFRVTARD
EWVFADMDLLHKVVAPAIR-----MSLKLHQDQFTCPDEYEDPAVLYEAIQSFEK-KVVI
CHEGDPAWRGAVLSNKEELLTLRHVVDEGADEYKVLMLHRSFLSFKVIKVNKECVRGLWA
GQQQELIFLRNRNPERGSIQNNKQVLRNLINSSCDQPLGYPMYVSPLTTSYLGTHRQLKN
IWGGPITLDRIRTWFWTKWVRMRKDCNARQ-HSGGNIEDV-DGGGVP---TSGGNNAPNG
GSQESSTEQPRKGGFQHGVSSC--EGTQRTG----RRKGRSQSVQAHSALSQRPPMLSSS
GPILESRQPFLQTSTSVHELAQRLSGSRLSLHTSATSLHSQPPPVTTTGH-LSVRERAEA
LIRSSLGSSTSSTLSFLFGKRSFSSALVISGLSAAEGGNTSDTQSSSSVNIVMGPSARAA
SQATRHLSE-PCEPTDTT-EQGQVRDRRLAEAVAE-TLRVVCRR-ASQEDMGLDDTASQQ
SASDEQ

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--------------------------------------------LNALTIDAFSISNYRR
LGTXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXX--XXXXXX
X--XXXX---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---XXXSAMLFF
QMIATSIFSTPLSPFLGSVIFITSYVRPVKFWEKNYXXX---XXXXXXXXXXXXXXXXXX
ND-DNNLNSIFYEHLTRALQESLCGDLVLGRWGNYSSGDCFILASDYLNAFVHLIEIGNG
LVTFQLRGLEFR-GTYCQQREVEAIMEGDEDDRGCCCCKPGHLPHLLSCNAAFNLRWLTW
EITRTQYILEGYSIIDNNAATMLQVFDLRRILVRYYIKSIIYYMITSPKLFSWIKNESLL
KSLQPFAKWHYIERDLAMFNINIDDDYVPCLQGITRASYCNVYLEWIQYCARKRQ

PF05041 // ENSGT00390000013164_1_Domain_0 (1856, 2089)

EPAK-
NVN-VDSDEDSALVTLSFALCILGRRALGTAAHNMAISLDSFLYGLHALFKGDFRITARD
EWVFADMDLLHKVVAPAIR-----MSLKLHQDQFTCPDEYEDPVVLYEAIQSFEK-KVVI
CHEGDPAWRGAVLSNKEELLTLRHVVDEGTDEYKVIMLHKSFLSFKVIKXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXMRKDCDAGQQSG-GNIEDMDRGAGVP---PPTGNHVPGG
ESQESSTEQPRKDGTRHWSP-H--EGTRRTG----RRKGRSQSVQAHGTLSQRPPILSSS
GPILESRQAFLQTSTSVHELAQRLSGSRLSLRSA-ASWHSKAPPAHTGDL---RFRRSRA
LIRSSLGSSTS-SLSFLFCKRSFSSALVISGLSAAEGGNTSDTQSSSSVNIVMGPSTRAP
GHATRHFSE-PCESTEAT-EQGQFRDHRLAEAAVR-NVGVICRR-ASQEDMGLDDTTSQQ
SASDEQ

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--------------------------XSQVLQLLR-------QGVWAALTGGWYHDPEQS
KFTNSC--H-------LYLWLFLL-------LLP--------LALHLAFPPSAI----TV
FFYCSSVTVFFTVIKVVSYRLHLMFDKGEVIQQKQSRKKEKTNKDKEAI--SEPVTNHKI
PS---NRQIQDSKKEEGGRNLSTPPLRCSSRGQSPNSHHSST-PLELPAQETVEDLKGVI
LSEDQPIAP-ESSTSPGIRRESLPASQVRTLEATPKSATPVKPAATETVINGKGTERGS-
KGQ-PPVRHRSEGG-LVDRGPLKKLPHLSLSQYDLLATDVSFQPWGSENSVLI-PEPASC
HQCSIQEQLQSRSPQDSLSSS-CPQCDTVTIRPA-EELVG--------------------
----TSCQEHLPLHQEVDYSESEVAVTLIDTSQPGDPLSLHKPIKIVITMSSTANS-MTD
LESSLHLKVVGTERTGLKSDAELATPGGASPPNT-EQTRIPVITLELSEDGG--GSTACP
EGGGSGWASERLQ-AEVSSSQCGPGYYTSGEVECATKDHSPSS-WSPWATAPPLTFPVAS
E-------SEAGKEGQANLDPSSCKNSHEKRHAWVLSVDSGTDVFLSKSSGEVIND-KEK
TMPTSKSDLEAKEGQLPNESNFLEFVSLLESINTSKVVAAEQLTGSAGQNEEGGLLR---
-------GNCSQEKKEEILESEKPTGQN-----FKQRKPDLQSQDHTGTSPVFIQPAKTP
AFFQGNRQRQIIYRVTSQQDSSVLQVISGPETSVQEEMSVDAMHVFIDEH-GEIRSCYLK
SGNQKEGLLQHPALNYDCVFQAREIQVSSSSTETSESQDPSSGDPAVSALQQQLLLMVAR
RTQSETPRH-----------VSQDLEDSSCSSTQGKFNREQFYKFIIFPGKWIKVWYDRL
TLLALLD---RTEDVKENVLAVLLIVLVSLLGFLTLNRGFCKDMWVLLFCLVMASCQYSL
LKA----------SVQPDPASPIHGHNQIITYSRPIYFCVLCGLILLLDTGAKARHPPRY
IVYGLKLFSPVSLQSARDYLIAFLYCFPAISLLGLFPQINTFCIYLLEQIDMLFFGGSAV
SGLTSAV--YGVARSVLAAALLHAVCFSAVK-EPWSMQHIPALFSAFCG-LLVALSYHLS
RQSSDPSVL-MSFIQCRLFPKFLHENL---EEAVADPLPKKMK--------DSVKDMLKS
DLLVCAVAAVLSFAVSASTVFLSLRPFLSIVLFALAGSVGFVA-HYILPQLRKHHPWMWI
SHPILKNKEYHQRELRDVAHLMWFERLYVWLQCFEKYILYPAIILNALTIDAFSISNYRR
LGTHWDIFLMIV--AGMKLLRTSFCNPV--HQFINLGFTVIFFHFDYKDISESFLLDFFV
VSILFSKATLGDLLHKLQFVMTYVAPWQMAWGSSFHVFAQLFAIPH--------SAMLFF
QTIATSVFSSPLSPFLGSVIFITSYVRPVKFWEKNYNTR---RVDNSNTRLAVQIERDPG
ND-DNNLNSIFYEHLTRTLQESLCGDLLLGRWGNYSSGDCFILASDDLNAFVHLIEIGNG
LVTFQLRGLEFR-GTYCQQREVEAIMEGDEDDRGCCCCKPGHLPHLLSCNAAFHLRWLTW
EIAQTQYILEGYSILDNNAATMLQVFDLRRLLIRYYIKSIIYYMVTSPKLLSWIKNESLL
KSLQPFAKWHYIERDLAMFNINIDDDYVPCLQGITRASFCNVYLEWIQYCTRKTQEPSK-
P--V

PF05041 // ENSGT00390000013164_1_Domain_0 (1865, 2098)

VDSDEDSALVTLSFALCVLGRRALGTAAHSMAISLDSFLYGLHALFKGDFRITARD
EWVFADMDLLHKVVAPAIR-----MSLKLHQDQFTCPDEYEDPAVLYEAIQSFEK-KVVI
CHEGDPAWRGAVLSNREELLTLRHVVDEGTDEYKVIMLHRSFLSFKVIKVNRECVRGLWA
GQQQELVFLRNRNPERGSIQNNRQVLRNLINSSCDQPLGYPMYVSPLTTSYLGTHRQLKS
VWGGPITLNRVRTWFQTKWLRVRKDCNTRQ-HSSSNVEDA-DGGGAP---GAGGSHARNG
GSQENSTEQPRKGGSREGTQGT--GGTQAQG---CRRKGRSQSVQAHSTLSQRPPVLSSS
GPILESHQAFLQTSTSVHELAQRLSGSQLSLHTSAGSVHSQPPPVTTTGH-LSVRERAEA
LIRSSLGSSTSSTLSFLFGKRSFSSALVISGLSAAEGGNTSDTQSSSSVNIVMGPSGRAT
GQARRHFSE-SCEPTDTI-EQGQLRERRLAEAVAD-TLGVVCRR-ASQEDMGLDDTASQQ
SASDEQ

------------------------------------------------------------
-------------------------MVSQVLQLLR-------QGVWAALTGGWYHDPEQS
KFTNSC--H-------LYLWLFLL-------LLP--------LALHLAFPPTAI----TV
FFYCSSVTIFFTVIKLISYRLHLMFDKGEVIQQKPSRKKEKPNKDKEAN--SEHITNHKI
PS--NNRQIHNGKKEEGHGNLSTPPLRCSSRGQSINSQHSSG-PSELPAQETVEDLKGVI
LSEDQPVPP-ESSTSPGIKMESLPASQVRMPETTPKSATPVKPVATETLINGKGKERGS-
KGQ-PPLRHRSEGG-LVDKGPLKKLPHLSLSQYDLLETDVSFQPWGSENSVLI-PEPPGC
PQGSMREKLQSRSPQDSLSSS-CPQCNTITVKPA-EEPVD--------------------
----TSCQVDLPLSQEVNCSDSEVAVTLIDNSEPGDPLSLHEPIKIVITMSSTQNS-MTD
LENSLHLKVVSTERTGLRSDAEPATPAVASPPNT-EQIRIPVITLELSEAGE--AGNTCP
KGNGSERMSERSK-AEASSNQYSS--YRSGVRESATKDCSPSS-QNPRETAPPLTPAVAS
E-------SEMGKEGQANLDPSSCKNSHEKRHARVLSVDSGTDVFLSKSSAEIIND-KEK
TMPTSKSDLEAKEGQIPNESNFLEFVSLLESINTSKVVASNPSNGSAEQKEESGLLQ---
-------DNCSQEKKEEILESEKPPGQN-----SKQGKPDLQSQDRTGTSPVFTQPAKTP
AFFQGNRQRQIIYRVTSQQDSSVLQVISGPETSVQEEMSVDAMHVFIDEH-GEIRSCYLR
SGNQKEGPLQHPPSNCDCLSQAREMQVSSSSTTTSESQDPSSGDPAVSALQQQLLLMVAR
RTQSETPR-----------HVSQDLEDSSCSSTQGKFNREQFYKFIIFPGKWIKVWYDRL
TLLALLD---RTEDVKENVLAVLLIVLVSLLGFLTLNQGFCKDMWVLLFCLVMASCQYSL
LK-----------SVQPDPASPIHGHNQIITYSRPIYFCVLCGLILLLDTGAKARHPPSY
VVYGLKLFSPVSLQSARDYLIVFLYCFPAISLLGLFPQINTFCIYLLEQIDMLFFGGSAV
SGITSAV--YSVARSVLAAALLHAVCFNAVK-EPWSMQHIPALFSAFCG-LLVALSYHLS
RQSSDPSVL-MSFIQCKLFPKFLHENL---EESVADPLPKKMK--------DSVKDVLKS
DLIVCAVAAVLSFAVSASTVFLSLRPFLSIVLFALAGSVGFVT-HYLLPQLRKHHPWMWI
SHPVLKSKEYHQRELRDVAHLMWFERLYVWLQCFEKYVLYPAIILNALTIDAFSISNYRR
LGTHWDIFLMII--AGMKLLRTSFCNP-V-HQFVNLSFTVIFFHFDYKDISESFLLDFFM
VSILFSK--LGDLLHKLQFVMTYVAPWQMAWGSSFHVFAQLFAIPHSA--------MLFF
QTIATSVFSTPLSPFLGSVIFLTSYVRPVKFWEKNYNTR---RVDNSNTRLAVQIERDPG
ND-DNNLNSIFYEHLTRALQESLCGDLILGRWGNYSSGDCFILASDDLNAFVHLIEIGNG
LVTFQLRGLEFR-GTYCQQREVEAIMEGDEDDRGCCCCKPGHLPHLLSCNAAFHLRWLTW
EITRTQYILEGYSIIDNNAATMLQVFDLRRILIRYYVKSIIYYMVTSPKLLSWIKNESLL
KSLQPFAKWHYIERDLAMFNINIDDDYVPCLQGITRASFCNVYLEWIQYCARKRQEPSK-
TV--V

PF05041 // ENSGT00390000013164_1_Domain_0 (1866, 2097)

DSDEDSPLVTLSFALCVLGRRALGTAAHNMAISLDSFLYGLHALFKGDFRITARD
EWVFADMDLLHKVVAPAIR-----MSLKLHQDQFTCPDEYEDPVVLYEAIQSFEK-KVVI
CHEGDPAWRGAVLANREELLTLRHVVDEGTDEYKVIMLHRSFLSFKVIKVNKECVRGLWA
GQQQELIFLRNRNPERGSIQNNKQVLRNLINSSCDQPLGYPMYVSPLTTSYLGTHRQLKN
VWGGPITLNRVRTWLQTKWLRMRKDCNAR-QHSSGNIEDADGGGAP----AAGGSNAPGG
GSQD-SVEQPRKGGSQPGASTH--EGTQGTG----RRKGRSQSVQAPSALSQRPPTLSSS
GPILESRQAFLQTSSSVHELAQRLSGSRLSLHASVASLHSQPPPITTTGH-LSVRERAEA
LIRSSLGSSTSSTLSFLFGKRSFSSALVISGLSAAEGGNTSDTQSSSSVNIVMGPSARAT
SQATRHFSE-PCEPTDAT-EQGQLRDRRLAEAVAE-TLGVICRR-ASQEDMGLDDTASQQ
SASDEQ

------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------AFPPNAI----TV
FFYCSLVTIFFTVIKLVSYRLHLMFDKGELIQQTPSRKKEKPDKDKEAN--SNHITNHKN
PXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXX-XXXXXXXXXXXXXXXVI
LSEDQPGAP-VSSTSPGVKTESLPVSKANARETTTTPARPVTPAMAERRIGDQG------
KGR-PPFHHRSEGG-LVDKEALRKSPHLSLSQYDLLETDVSFQPWGSENSVLT-PDPGHH
TRDSIRERMQSQASQDSLSSS-CPQCDTVIAKPV-QDAAAA-------------------
------SQQCWPVNQDVDYSGSEVAVTLIDTSQPGDPLSLHEPIKIVITMSSTQNS-MTD
LESSLHLKVIGTEGTGLESDAQSATPGVAGPPNV-EQMRIPVITLELSEDGG--GGIVCP
EGTGGDRTPERLM-AEPPSNQCSG--YESGEGGNAAKDCSPSP-RDHSATTPPPTTNVVS
D-------SPGAVEGQATLDPSSCRTSHEKRHARVLSVDSGTDVL-SKSSADIISD-KEK
TIPTSKSDLEAKEGQMPNESNFLEFVSLLESINTSKGVASDQGSEPAEQTKDSGLLG---
-------DDRSQEKKEEILESEKPSGHS-----AKQGKSDIQSQDHTSTSPGLTEPAKIX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXDIQISSSSTTTSESQDPSSGDPTVSALQQQLLLMMAR
RTQPETPRXXXX--XXXXXXXXXXXXXXXXX---------XXXXXXXXXXXXXXXXXXXX
XXXXXXX---XTEDVKENVLAVLLIVLVSLLGFLTLNQGFCKDIWVLLFCLVMASCQYSL
LK-----------SVQPDPASPIHXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXFLYCFPAISLLGLFPQINTFCIYLLEQIDMLFFGGSAV
SGMLSAV--YSVARSVFAAVVLHVLCFSAVK-EPWSTQHIPALFSAFCG-LMVALSYHLS
RQSSDPSVL-LSFIQCRLFHKLLHQNL---EESPEDPLPKKMK--------DSVKDVLKS
DLLICSVAAVLSFAVSASTVFLSLRPFLSIVLFALAGAVGFVT-HYVLPQLRKHHPWMWI
SHPVLKNKEYQQREVTDVAHLMWFERLYVWLQCFEKYILYPAVILNALTIDAFAISNYRR
LGTHWNIFLMVI--AGMKLLRTSFCNPV--HQFTHLGFTVIFFHFDYKDISESFLLDFFM
VSILLSK--LGDLLHKLQFIMTYVAPWQMAWGSSFHVFAQLFAIPH--------SAMLFF
QTFATSIFSTPLSPFLGSVIFIASYVRPVKFWEKNYXXX---XXXXXXXXXXXXXXXXXX
XX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSIIYYMVTSPKLLSWIKNESLL
KSLQPFAKWHYIERDLAMFNMNIDDDYVPCLQGITRASYCNVYLEWIQYCARKRQEPSK-
N---LDSDEDSPLVTLSFALCILGRRALGTAAHNMALXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXX-----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XK

PF05041 // ENSGT00390000013164_1_Domain_2 (2043, 2098)

QQELKFFRNRNPERGSIQNNKQVL-NLINSSCDQPLGYPMYVSPLTTSYLGTHRQLKN
VWSGPITLDGLRAWFRAKWLRMLKDGGAGC-QGAGNIEDV-DGGGAP---PTGGSSAPSG
ESRESSTEQPRKDGPRHWSP-R--EGPRRTG----RRKGRSRSVQASGALSQTPPVLRSS
GPLVEGHPAFLQTSTSVHELAQRLSGSRLSLHTSAASLHSQPPPVTATGH-LSVRERAEA
LIRSSLGSSTSSTLSFLFGKRSFSSVLVISGLSAAEGGNTSDTQSSSSVNITMGPSARAA
GQSAR-------------------------------------------------------
------

------------------------------------------------------------
-------------------------MGSQVLLLLR-------QGVWAALTGGWYHDPEHS
KFTNSC--H-------LYLWLFLL-------LLP--------LALHLAFPPTAV----TA
LLYCGLVTIFFAAIKLVSYRLHLMFDEGEVICQRPPRGREKSPTVREAK--GERTASHKN
PR-----HLHSTKKAGIPTGHPTPPLHGRSSGHSGHSHPSSGLS------------VGVA
LSDDHPP----PSAQPGTGTRCLPASQPQGLAPAPR-------------MEEAEKPR-R-
AET-RPARHRSEGG-LEDSGALKTMPPLSLSQ-----RDVSFPPWGSEHSIPG-PEAPSR
E-------------PGALSSS-CPQCNTAVARPL-AQGAG--------------------
----SP--SAVALNQDVDGSSSELATSLPRAKQRGDPLSACEPIRIVVTMSSTPNS-VSD
TGSSLDLQATRAGRDVTM----------LSSDADHEQTRGPVVTLALPEDGA--E-----
SGQGRERTPEGAE-AG-ASGQCWA--CGSGSGD------------GCCASREAITP----
---------GVGSEGQASLDPASCRSGQEKRHARVLSVGSGTDIFAA-----VANS-KEG
PMPASKSDLEAKGGQVPDESNFLEFVSLLESISTSPGPGQRPP-----------------
------------GETPPALPTNEPGGPD-----PGPGKPDAASREPAS-----TSPACTP
PVFQGGRQRQIIYRVTSQQDSSVLQVISGPETSGQEETSADAMQVFIDER-GEIRSCYLK
SGKQKEGPAPCPVASLDGVAHVRETLVSSSSTTTSGSPDPSSGDPVVSALQQQLLLMAAR
RTPSEPPR-----------HVSQDLEDSSCSSAQGKFNREQFYKFIIFPGKWIKVWYDRL
TLLALLD---RTDDIKENVLAVLLGVLVSFLGFLTLNRGFCKDLWVLLFCLVMASCQYSL
LK-----------SVQPDPASPVHGHNQIITYSRPVYFCVLCSLILLLDAGAKARHPPRF
VMYGLRLFSPQSLQLARDGLIGFLYCFPALSLLGLFPQINTFCTYLLEQIDMLLFGGSAV
SGILSAL--YSVGRSVLVTVLLHAVCFSAVK-EPWSMQHIPALFSAFCG-LLVALSFHLS
RQSSDPSVL-LSFIQCNMFPKYLQQNL---EESAADPLPQKMK--------DSVRGVLRS
DLLICSVAAVLSFAVSASTVFLSLRPFLSVVLFALAGIVGLIT-HHLLPQLRKHHPWLWV
SHPILR----------KVTRLMWFERLYVWLQCFEKYILYPAITLNGLTLNAFSISNHRR
LGTHWDIFLMII--AGMKLLRTSFCNP-V-HQFINLSFTAIFFHFDYKDTSEGFLLDFFM
VSILFSK--LGDLLHKLRFVLAYVAPWQMAWGSSFHVFAQLFAVPHSA--------MLFF
QTVATSIFSTPLSPFLGSVIFLTSYVRPVKFWEKNYKTR---RVDNSNTRLAVQIERDPG
ND-DNNLNSIFYEHLTRTLQESLCGDLLLGRWGNYSSGDCFILASDDLNAFVHLIEIGNG
LVTFQLRGLEFR-GTYCQQREVEAIMEGDEDNRGCCCCRPGHLPHLLSCNAAFRLRWLTW
EVTRTQYVLEGYSIMDNNAATMLQVFDLRRTLIRYYIKSIIYYMVASPKLLSWVKNEALL
KSLQSFAKWHHIERDLAMFHMNIDDDFVPCLQGITRASFCTAYLEWIQFCAGKRQEPSK-
ALGSV

PF05041 // ENSGT00390000013164_1_Domain_0 (1866, 2097)

DSDEDSPLVTLSFALCILGRRALGTAAHNMALSLDSFLYGLHTLFKGDFRVAAPD
EWVFADMDLLHKVVAPAIR-----MSLKLHQDQFTCPDEYEDPAVLFEAIQAFEK-KVVI
CHEGDPAWRGAVLSNKEELLTLRHVVDEGVDEYKVIMLHRGLLSFKVIKVNRECVRGLWA
GQQQELIFLRNRNPERGSIQNNKQVLRNLINSSCDQPLGYPMYVSPLTTSYLGTHRQLQS
IWGGPISLGSVTTWFRARWLRMRKDCSAG-QRSGGIEEGDAGGAAP-------GSQAPCA
NSRESGVDQARKGGAQHWPSPR-A-GPPRTG----RTKGRSQSVQPHSALSQRPAVLSSS
GPLVEGRQAFLQTSSSVHELAQRPLGSRLSLHTSAASLHSQPPPASAAGH-LSVRERAEA
LIRSSLASSTSSTLSFLFGKRSFSSALVISGLSAAEGGNTSDTQSSSSVNIVMGPSARAA
GQATRHHSE-PCDPTEAA-EQRRLHEGRL----AE-NPGMMCRR-ASQEDMGLDDTASQQ
SASDEQ

------------------------------------------------------------
-------------------------MVSQVLQLLR-------QGVWAALTGGWYHDPEQS
KFTNSC--H-------LYLWLFLL-------LLP--------LALHLAFPPNVI----TA
LFYCSSVTVLFTVIKVVSYRLHLMFDKGEVIQQRSPRQVEKPKKDREAN--SEHATNPKI
PS--STRPIHSSKKEEIGRSVPTPPLHCSSRGQSLSSHRSSG-PLELPAQETVEDLKGVV
LSEDHPGAP-VSSTSPGIRTDSLPASQVCLPEPMRRSAEPTKPAVPEALISGKGRGQEG-
QGQ-HPPRHRSEGG-LVDKGDLKKLQRLSLSQYDLLETDVSFQPWGSENSVLI-PEPLTC
HQDSISKQLQSKSPQDSLSNS-CPQCHTVMAKPT-QRLVG--------------------
----TSSHMALPFSQGVNSSDSEVAVTLIDTSQPGDPLSLHEPIKIVITMSSTSNS-TTE
VGSSLHLKVTGTEQVSPGAHIEPASPRK-HPTNA-EHIRIPVITLELSEDGG--GSVTVP
EGQRNRRTSDQLNVG--DSDQCSS-----GE--------------HAWEPAQTPTSAVAS
E-------AEGETDGQASLDPVSCRGSHEKRHARVLSVDSGTDVFLSRSSTEVVSD-KEK
TIPTSKSDLEAKEGQIPNESNFLEFVSLLESINTSKVVASTQPKDPADQHGAGE------
-AKGLREDHYSQGKKEEILEKEKPSGQQ-----SKPEKPELQSQDHPGTSPMFSPPARTT
ALFQGNRQRQIIYRVTSQQDSSVLQVISGPETSVQEEMSVDAMHVFMDEH-GEIKSCYLK
SGNQKESSFQYPPLSEDCASQGREVHLSSSSTTTCESPDPSSGDPAVSALQQQLLLMVAR
RTHSETPR-----------HVSQDLEDSSCSSAAGKFNREQFYKFIIFPGKWIKVWYDRL
TLLALLD---RTEDVKENVLAIVLSILVSLLGFLTLNRGFCRDLWVLLFCVVMASCQYSL
YN-----------S--------DAGHNQIITYSRPIYFCVLCGLILLLDAEAKSRHPPRY
VVYGLKLFSPESLQTARDHLIVFLYCFPVISLLGLFPQINTFCTYLLEQIDMLLFGGSAV
SGIVSAV--YSVGRSILAAALLHVFCFSAVK-EPWSTQHIPALFSAFCG-LLVALSYHLS
RQSSDPSVL-LSFIQCRLFPKFLHQSL---EESATDPLPQKMK--------DSVKDVLRS
DLVVCSVAAVLSFAVSASTVFLSLRPFLSVVLFALAGTVGFIT-HHLLPQLRKHHPWMWV
SHPVLKSREYQQREVGDIAHLMWFERLYVWLQCFEKYILYPAIILNALTIDAFSISNYRR
LGTHWDIFLMII--AGMKLLRTSFCNPV--HQFTHLSFTLIFFHFDYKDFSESFLLDFFM
VSILLSK--LEDLLHKLQFVLAYVAPWQMAWGSSFHVFAQLFAIPHIL--------STSQ
ELTM--TF---------------------YSFVAPSSTK---RVDNSNTRLAVQIERDAG
GD-DNNLNSIFYEHLTRTLQESLCGDLVLGRWGNYSSGDCFILASDDLNAFVHLIEIGNG
LVTFQLRGLEFR-GTYCQQREVEAIMESDEDDRGCCCCQPGHLPHVLSCNAAFHLRWLTW
EVTRTQYILEGYSIIDNNAATMLQVFDLRRVLIRYYIKSIIYYMVTSPKLLSWVKNESLL
KSLQPFAKWHHIERDLAMFNINIDDDYVPCLQGITRASYCNVYLEWIQYCAGKRQEPSK-
T---V

PF05041 // ENSGT00390000013164_1_Domain_0 (1866, 2097)

DSDEDSPLVTLSFALCILGRRALGTAAHNMAMSLDSFLYGLHALFKGDFRITARD
EWVFADMDLLHKVVAPAIR-----MSLKLHQDQFTCPDEYEDPAVLYGAIQSFEQ-KVVI
CHEADPAWRSAVLSNKEELLTLRHVVDEGTDEYKVIMLHRGFLSFKVIKVNKECVRGLWA
GQQQELIFLRNRNPERGSIQNNKQVLRNLVNSSCDQPLGYPMYVSPLTTSYLGTHQQLRN
VWGGPVTLNSLRTWFQARWLSMRKDCNTG-QSSRGAIEDLDGGGAPNG------------
---DGSVEQPHKGGTQHWVSPRE--GAQRTG-----RKGRSQSVQAPSVLSQRLPNLSSS
GPIVESRQAFLQTSTSVHELAPRPLGSRLSLHTSATSLHSQPPPVTTTGH-LSVRERAEA
LIRSSLGSSTSSTLSFLFGKRSFSSALVISGLSAAEGGNTSDTQSSSSVNIVMGPSARAA
GHATRHFSE-PCDPTEAA-EQRQLRDRRLAEAVAE-NLGVMCRR-ASQEDMGLDDTASQQ
SASDEQ

------------------------------------------------------------
-------------------------MVSQVLQLLR-------QGVWAALTGGWYHDPEQS
KFTNSC--H-------LYLWLFLL-------LLP--------LALHLAFPPNAI----IV
FFYCSAVTIFFTIIKLVSYRLHLMFDKGEVIQQKPSRKEEKPNKDKEAK--GEHITNHKN
PS--NNRQIHNGKKEEASRNLSTPPLRCSSRGQSITSHHSSG-PLELSAQETVEDLKGVI
LLEDHPIAP-VSSTSPGIKVESLPASQAHMLETTPKSVIPVKPVATETLINGKGKERGG-
KGQ-PPLRHRSEGG-LVDKGPLKKLPHLSLSQYDLLETDVSFQPWGSENSVLI-PEPVSC
PQGSIRERVQSKSPQDSLSSS-CPQCDTIVAKPV-EEPADTSCQVD--------------
----TSCQVDLPLHQEVDSSDSEVAVTLIDTSQPGDPLSLHEPIKIVITMSSTPNS-MTD
LESSLHLRVVGTEKTSVKSDAEPTNPGAAGSPHA-EQISIPVITLDLPEGGG--GGVPCP
EGNRSERTPERLK-TRVSTNQCSG--YGSGEGGNAIKDHSSSS-REPWESVSRLTPDTAS
E-------SKVGKEGQTNLDPSSCKSSHEKRHARVLSVDSGTDV-LSKSSAEIVND-TEK
TMPTSKSDLEAKEGQMPNESNFLEFVSLLESINTSKMTASNQLNGSAEQNEESGLLR---
-------DNCSQEKKEEILENEKPSGHS-----SKQGKPDLQSQDHTSTGPACTQPAKTT
AFFQGNRQRQIIYRVTSQQDSSVLQVISGPETSVQEEISVDAMHVFIDEH-GEIRSCYLK
SGNQKEGPLQPLSSNSDCLSQAREMQVSSSSTTTSESQDPSSGDPAVSALQQQLLLMVAR
RTQSETPRH-----------VSQDLEASSCSSTQGKFNREQFYKFIIFPGKWIKVWYDRL
TLLALLD---RTEDIKENVLAILLIVLVSLLGFLTLSQGFCKDMWVLLFCLVMASCQYSL
LK-----------SVQPDPASPIHGHNQIITYSRPIYFCVLCGLILLLDTGAKARHPPSY
IVYGLKLFSPVFLQSARDYLIVFLYCFPAISLLGLFPQINTFCTYLLEQIDMLFFGGSAV
SGITSAV--YSVARSILAAALLHAVCFSAVK-EPWSMQHIPALFSAFCG-LLVALSYHLS
RQSSDPSVL-MSFIQCRLFPKFLHQNL---EESAADPLPKKMK--------DSVTDVLKW
DLIVCAVVAVLSFAVSASTVFLSLRPFLSIVLFALAGAVGFVT-HYVLPQLRKHHPWMWI
SHPILKNKEYHQREVRDVAHLMWFERLYVWLQCFEKYILYPALILNALTIDAFLISNHRR
LGTHWDIFLMIIA--GMKLLRTSFCNPV--YQFINLSFTVIFFHFDYKDISESFLLDFFM
VSILFSK--LGDLLHKLQFVLTYVAPWQMAWGSSFHVFAQLFAIPH--------SAMLFF
QTIATSIFSTPLSPFLGSVIFITSYVRPVKFWEKNYNTR---RVDNSNTRLAVQIERDPG
ND-DNNLNSIFYEHLTRTLQESLCGDLVLGRWGNYSSGDCFILASDDLNAFVHLIEIGNG
LVTFQLRGLEFR-GTYCQQREVEAIMEGDEEDRGCCCCKPGHLPHLLSCNAAFHLRWLTW
EITQTQYILEGYSILDNNAATMLQVFDLRRILIRYYIKSIIYYMVTSPKLLSWIKNESLL
KSLQPFAKWHYIERDLAMFNINIDDDYVPCLQGITRASFCNVYLEWIQHCARKRQEPST-
T---L

PF05041 // ENSGT00390000013164_1_Domain_0 (1866, 2097)

DSDEDSPLVTLSFALCTLGRRALGTAAHNMAISLDSFLYGLHALFKGDFRITARD
EWVFADMDLLHKVVAPAIR-----MSLKLHQDQFTCPDEYEDPAVLYEAIQSFEK-KVVI
CHEGDPAWRGAVLSNKEELLTLRHVVDEGADEYKVIMLHRSFLSFKVIKVNKECVRGLWA
GQQQELIFLRNRNPERGSIQNNKQVLRNLINSSCDQPLGYPMYVSPLTTSYLGTHRQLKN
VWGGPITLDRIRTWFWTKWVRMRKDCNARQ-HSGGNIEDV-DGGGAP---TTGGNNAPSG
GSQESSAEQPRKGGAQHGVSSC--EGTQRTG----RRKGRSQSVQAHSALSQRPPMLSSS
GPILESRQTFLQTSTSVHELAQRLSGSRLSLHASATSLHSQPPPVTTTGH-LSVRERAEA
LIRSSLGSSTSSTLSFLFGKRSFSSALVISGLSAAEGGNTSDTQSSSSVNIVMGPSARAA
SQATRHLSE-PCEPPDAT-EQGQLHDRRLAEAVAD-TLGVVCRR-ASQEDMGLDDTASQQ
SVSDEQ

------------------------------------------------------------
-------------------------MASPLLQLLL-------QGVWAALTGGWYHDPEHS
KFTNSC--H-------LYLWLFLL-------LLP--------LALHLAFPPNAL----TV
LLYCGLVTIFFAVIKLVSYRLHLMFDKGEVVQQKPPRKRDKPRQDREAG--SQHTASPKH
PS--NTRQIHSGKKEELRGNLPTPPLRCSSRGQSVHSQHSSG-LLELSAQETVDDLKGAV
LSEDQPEAAVVSATSPGIRSESLPAAQVRTPGHVSRPAGPAKPLTSEMLINGKWKDQGA-
MGR-RPSRHRSEGG-LVDTGAMKKLPHLSLSQYDLLEADVSFQPWSSENSVLL-PEAVSC
HQGSTKGQFQSMMPQDSLSSS-CQQCNTVVAEPT-WEPAS--------------------
----TPCHVDPPSNQEGDHSDGEVTVTLVDTSQPGEPLSLHEPIKIVITMSSTPNS-MSD
MESSLHLKVTSSDRTGFRPDAEPAGPAMASSADS-EPVRIPMITLELSEERG--GGASCP
QDNESERTPKRLQ-VEMSPNLCSE------------------------------SPGVAS
E-------PEEGREDQADLDPTSWKNSHERRHARVLSVDSGTGVFLSRTSTEAVND-RER
PIPTSKSDLEAKEGQIPNESNFLEFVSLLECISTSKVVPSNGVQSSVEQNEASRAPE---
-------DHASQGSKEKAVESEKPCRHD-----PKPGKPDLPSRDHARASPVLTQPAKTT
ASFQGNRQRQIIYRVTSQQDSSVLQVISGPETSVQEDTSVDAMHVFIDEH-GEIRSCYLK
SGNQKEGSFQHPPSN-----HAREILLSSSSTTTSGSPDPSSGDPAVSALQQQLLLMVAR
RTQSETPRH-----------ACRDLEDSSCSSAQGKFHREQFYKFVIFPGKWMKVWYDRL
TLLALLD---RTEDVKENLVAILLSVLVSLLGFLTLNRGFCKDLWVLLFCLVMASCQYSL
LK-----------SVQPDPASPIHGHNHIIAYSRPIYFCALCGLILLLDAGAEARHLPTY
SVYGLKLFSPESLQSVRDHLIGFLCCFPAISLLGLFPQINTFCTYLLEQVDMLLFGGSAV
SGMVSAV--HSVGRSVLAVALLHVLCFSAVK-EPWSTQHIPALFSAFCG-LLVALSYHLS
RQSSDPSVE-RSV-----WVGCINEGV---SVLPSSPLGRSMEGPTLPLAFSLQKDILRS
DLVVCSVAAILSFALSASTVFLSLRPFLSIVLFALAGTVGLVT-HHLLPQLRKHHPWMWV
SHPVFKSKEYQQQEAQDVAHLMWFERLYVWLQCFEKYILYPAIILNALTIDAFSVSNYRR
LGTHWDIFLLTT--AAMKLLRASFCNPA--HQFIHLGFTVIFFHFDYKGISESFLLDFFI
VSIVFNK--LGDLLHKLQFVLAYVAPWQMAWGSSFHVFAQLFAVPH--------SALLFF
QAFASALFSTPLSPFLGSVIFITSYVRPVKFWEKSYNTK---RVDNSNTRLAVQMERDPG
ND-DNNLNSVFYEHLTRTLQESLCGDLVLGRWGNYSSGDCFILASDDLNAFVHLIEIGNG
LVTFQLRGLEFR-GTYCQQREVEAIMEGDEDDRGCCCCKPGHLPHLLSCNAAFHLRWLTW
EVARTQYILEGYSILDNNAATMLQVFDLRRILVRYYVKSIIYYLLASPKLLSWVKNESLM
KSLQPFAKWHYIERDLAMFNINIDDDYVPCLQGVTRASYCNAYLEWIQYCAGKRQEPSK-
ALDSV

PF05041 // ENSGT00390000013164_1_Domain_0 (1866, 2097)

DSDEDSPLVTLSFALCILGRRALGTAAHNMAISLDSFLYGLHALFKGDFRVTARD
EWVFADMDLLHKVVVPAIR-----MSLKLHQDQFTCPDEYEDPVVLYEAIQSFEK-KVVI
CPEGDPAWRGAVLSNKEELLTLRHVVDEGADEYKVIMLHRSFLSFKVIKVNKECVRGLWA
GQQQELIFLRNRNPERGSIQNNKQVLRNLINSSCDQPLGYPMYVSPLTTSYLGTHRQLQS
VWGWPVTLDRMRTWFRARWLRMRKDCSAGQQHSRGTAEEA-EGGGAP---SAGGSHAPSG
DSQENSMEQPRKEGAQRWASPR--GGAPSAG----RRKGRSQSVQAHSALCPRPPTLSSS
GPILENRQAFLQTSTSVHELVQRPSGSQLSLHTSAASLHSQPPPVTTTGH-LSVRERAEA
LIRSSLGSSTSSTLSFLFGKRSFSSALVISGLSAAEGGNTSDTQSSSSVNIVMGPSARAA
GQATRHFSE-SSEHSD-A-EPGQAHEQRLAEVVAE-NLGVLCRR-ASQEDMGLDDTASQQ
SASEEQ

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------MII--AGMKLLRTAFCNP-V-HQFIHLSFTVIFFHFDYKDISESFLLDFFM
VSILFSK--LGDLLHKLQFVMTYVAPWQMAWGSSFHVFAQLFAIPHSA--------MLFF
QTFATSIFSTPLSPFLGSVIFITSYVRPVKFWEKNYNTR---RVDNSNTRLVVQIEKDPG
ND-DNNLNSIFYEHLTRALQESLCGDLVLGRWGNYSSGDCFILASDYLNAFVHLIEIGNG
LVTFQLRGLEFR-GTYCQQREVEAIMEGDEDDRGCCCCKPGHLPHLLSCNAAFNLRWLTW
EITRTQYILEGYSIIDNNAATMLQVFDLRRILIRFYIKSIIYFMVTSPKLLSWIKNEPLL
TSLQPFTKWHYIERDLAMFNINIDDDYVPCLQGITRASYCNVYLEWIQYCAQKRQESSK-
N---L

PF05041 // ENSGT00390000013164_1_Domain_0 (1866, 2098)

DSDEDSPLVTLSFALCILGRRALGTAAHNMALSLDSFLYGLHTLFKGDFRITARD
EWVFADMDLLHKVVAPAIR-----MSLKLHQDQFTCPDEYEDPVVLYEAIQSFEK-KVVI
CHEGDPAWRGAVLSNKEELLTLRHVVDEGTDEYKVIMLHRSFLSFKVIKVNKECVRGLWA
GQQQELIFLRNRNPERGSIQNNKQVLRNLINSSCDQPLGYPMYVSPLTTSYLGTHRQLKN
IWSGPVTLDSIRTWFLTKWLRVRKDCDAG-QHHGGNIEDVDGGGAPPGGPPAGGSNAPSA
ESQESSTEQPRKAGTHHWLRSC-TGRSRTRW----RRKGRSQSVQAPGALGQRPPILSSS
GPNLESHQAFLQTSTSVHELAQRLSGSRLSLHTSAASLHSQPPPVTTTGH-LSVRERAEA
LIRSSLGSSTSSTLSFLFGKRSFSSALVISGLSAAEGGNTSDTQSSSSVNIVMGPSARAA
SQATRHFSE-PCEPTEAT-EEGQLHDHCLAEALAE-TLGVICRR-ASQEDMGLDDTASQQ
SASDEQ

------------------------------------------------------------
-------------------------MASQVLQLLR-------QGVWAALTGGWYHDPEHS
KFTNSC--H-------LYLWLFLL-------LLP--------LALHLAFPPNVL----TA
LFYCGLVTIFFAIIKLISYRLHLMFDKGEVVQHRSPRKRSKRRPEGEAS--SQHTASHKH
PG--NNRQIHSTKKEEPRGSLPTPPLRCSSQGRNVHSQH-SS-PLELPVQETVEDLKGVV
LSEDQPEAV-VSSTSPGIKSESLPASQGHTPEPTPRPAGPVKPIATEILTRRKGKEPGA-
TGQ-RPARHRSESG-LVNTEALKKLPHLSLSQYDLLETDISFQPWGSEHSALI-PQTTNC
PQGPTRTQSQSRSPQDSPSSS-CCQCNTVLAKPT-EEEELT-------------------
---RTSDPVELPLNQEVVDSDGEVAVTLIDTSQPGEPLSLHEPIKIVITMSSTPNS-MSD
LESSLQLKVTSSDETNVRPDTEPSGTGVEGPADA-EQVRVPLITLELTEDGG-GRDISCP
ARNGGERAPERMA-RM-PSDLCS----CSTKDGSPT------------------PSPSPT
P-------LSPRVEDQANLDPASCKSSHEKRHARVLSVDSGTDVFLSRSTKEVVSD-SEK
PIPTSKSDLEAKEGQIPNESNFLEFVSLLESINTSKVVAPDS---AAEQKEANQGPE---
-------DHADPGTKEETVESEKPSGHD-----PKPGKPDLPSQDHAIASPVFTQPAKTT
ALFQGSRQRQIIYRVTSQQDSSVLQVISGPETSVQEEMSLGAMHVFIDEH-GEIKSCYLK
SGNQKEGSSQHPPSNPDCISRAREILLSSSSTTTSESPDPSSGDPAISALQQQLLLMVAR
RTQSETPRH-----------MSQDLEDSSRSSAQGKFNREQFYKFIIFPGKWIKVWYDRL
TLLALLD---RTEDVKENVVAILLSVLVSLLGFLTLNRGFCRDLWVLLFCLVMASCQYSL
LK-----------SVQPDPASPIHGHNQIIAYSRPIYFCMLCGLILLLDAGAKARHPPSY
VVYGLKFFSPETLQSIRDHLIVFLCCFPVISLLGLFPQINTFCTYLLEQVDMLLFGGSAV
SGITSAV--YSVGRSVLVAALLHAFCFSAVK-EPWSTQHIPALFSAFCG-LLVALSYHLS
RQSSDPSVL-LSFIQCRLLPKCLHQNL---EESATDPLPQRMK--------DSVKDVLRS
DLVVCSAAAVLSFAVSASTVFLSLRPFLSIVLFALAGTVGLIT-HHLLPQLRKHHPWMWV
SHPVLKSKECQQREARDIAHLMWFERLYVWLQCFEKYLLYPAIVLNALTLNAFSISNYRR
LGTHWDIFLMII--AGMKLLRTSFCNPV--HQFANLGFTVIFFHFDYKDISESFLLDFFM
VSIVFTK--LGDLLHKLQFVLAYVAPWQMAWGSSFHVFAQLFAIPH--------SAMLFF
QTFATSIFSTPLSPFLGSVIFITSYVRPVKFWERSYNTR---RVDNSNTRLAVQMERDPG
SD-DNNLNSIFYEHLTRTLQESLCGDLVLGRWGNYSSGDCFILASDDLNAFVHLIEIGNG
LVTFQLRGLEFR-GTYCQQREVEAIMEGDEDDRGCCCCKPGHLPHLLSCNAAFHLRWLTW
EITRTQYILEGYRIIDNNAATMLQVFDLRRVFVRYYVKSIIYYMVTSPKLLSWVKNEPLL
KSLQPFAKWHHIERDLAMFNVNIDDDYVPCLQGITRASYCTVFLEWIQYCAGKRQELSK-
ALDHV

PF05041 // ENSGT00390000013164_1_Domain_0 (1866, 2097)

DSDEDSPLVTLSFALCILGRRALGTAAHNMAMSLDSFLYGLHALFKGDFRITARD
EWVFADMDLLHKVVVPAIR-----MSLKLHQDQFTCPDEYEDPAVLYEAIQSFEK-KVVI
CHEGDPAWRGAVLSNKEELLTLRHVVDEGADEYKVIMLHRGFLSFKVIKVNKECVRGLWA
GQQQELIFLRNRNPERGSIQNNKQVLRNLINSSCDQPLGYPMYVSPLTTSYLGTHKQLQS
VWGGPVTLNRMRTWFQTRWLRMRKDCSVGQRSG-GNIEDV-DGGAVP---SAVGSNAPSG
ESRDSSTEQPRKGGTQQWASPR--GGGHRAG----RRKGRSQSVQAHSAISQRPPTLSSS
GPILESHQAFLQTSSSVHELAQRPSGSRLSLHTSAASLHSQPPPVTTTGH-LSVRERAEA
LIRSSLGSSTSSTLSFLFGKRSFSSALVISGLSAAEGGNTSDTQSSSSVNIVMGPSARAA
GHATRHFSE-PCESIDTP-EQGQLPDRRL----AE-NLGVLCRR-ASQEDMGLDDTASQQ
SASDEQ

------------------------------------------------------------
-------------------------MVSQVLQLLR-------QGVWAALTGGWYYDPEHS
RFTNSC--H-------LYLWLFLL-------LLP--------VAVHLAFPPNAM----TV
FFYCSSVTVFFTIIKLVSYRLHLMFDKGEAVPPRPPREEERPGRDGEAD--GGRPANHKI
PS--STRPAVGGRKEEASPEHSSRPPRGSPGGHGVGSRHSAA-LLELPARETAEDLKGVV
LSEEQPGAL-ASSPSPASEA--------HVLESTAPAARPTKPAAAEE----SSRGRGGG
GEARPPPRHRSDGG-LVDKGALKKRPHLSLSQYDLLETDVSFQPWGSERSVPV-PEPMGG
ARGPPGEQMQGRSPQDSPSSS-CPHCDTVVPKPE-HELVD--------------------
----AARQVDPPSTQAADPSDSEVAVTLCDASHPGEPPSLQEPIRIVITMSSTPSS-VTD
GESSLPPRALGPESTGVRPGAAPGPPGAARPART-EQVTVPVITLELPGGG---GGGTCP
GGRGGRRTAERRA-AEAPSTQRSG--RESGDGGHATTSLSASP-RDPCEPAARL------
------------------------PASHEQGPPRGRSVDAGTDAVFSESSAGVISG-KEK
AMPTSKSDLEAKEGQTPNESNFLEFVSLLESVGGAKVAGSSQRGGPAEPDGDSGLPRGN-
----------RSPEKEAILEGERPSGPG-----SKQGTPDVPSRNHAGTGPGVAEPARIT
ALFQGSRQRQIIYRVTSQQDSSVLQVISGPETSVQDEMPAEAVHVFIDGH-GEIRSCYLK
SANQTEGPVQRQPSNCDGFSQAGXXXXXXXXXXXXXXXXXXXXXXXXXXXQRQLWLMVAQ
RTQPEATR-----------RPSRGPEDSSCSSTQGKFDREQFYKFVIFPGKWIKVWCDRL
ALLALLD---RTDDVQENVLAVSLFVLVSLLGFLTLSRGFGRDLWLLLLCHVMASCQYSL
LK-----------SVQPDPASPIHGHNRIITYSRPIYFCALCGLILLLDAGAKARRAPTH
TVYGLQLLAPESLRSARDLVMACLYCFPAISLLGLFPQVDTFCVYLLEQIDMLLFGGSAV
SGVTSAV--YSVGRSVASATVLHVLCFHAVK-EPWSTQHIPALFSAFCG-LLASLCYHMS
RQSSDPSVLLXXXXXXXXX-XXXXXXX---XXXXXXXXXXXXX--------XXXKDVLKS
DLVVCSVAAVLSFAVSASTVFLSLRXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXVAHLMWFERLYVWLQCFEKYVLYPAIILNAVTIDAFSISNYQR
LRTHWYVFLVTM--ASMKLLRASFCNPA--HQFVHLTFTVLFFHFDYKDISESFLLDFFM
VSILSSK--LGDLLRKLQFVMTYVAPWQMAWGSSFHVIAQLVAIPHSA--------LLFL
QTLASSILSSPLSPFLGSVIFITSYVRPVKFWEKNYXXXXXXXXXX---XXXXXXXXXXX
SD-GSSRNAIFYEHVTRALQATLCGDLALGRWGSYSSGDCFILASDDLNAFVHLIEVGNG
LVTFQLRGLEFQ-GTYCQQREVEAIMEGDEDDRGCCCCKPGHAPHLLSCNAAFNLRWLTW
EVTRTRYILESYSITDNNAATMLQVFDLRRLLIRYYVKXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPPK-
--

PF05041 // ENSGT00390000013164_1_Domain_0 (1863, 2098)

-SLDCDEDSPLVTLSFALCTLERRALETAAHGMALSLDSFLYGLHALFKGDFRMTAQD
EWVFADMDLLHKVVAPAIR-----MSLKLHQAQFTCPDEFEDPVVLYEAIQSFEK-KVVI
CHEGDPAWRGAVLSNREELLTLRHVVDEGAAEYKVIMLHRSFLSFKVIKVNRECVRGLWA
GQQQELVFLRNRNPERGSIQNSTQVLRNLIGSSCDQPLGYPMYVSPLTTSYLGSHGQLQG
VWAGPVTLDGIRSWFRTKWLRMRKGCSAG-QPAGGP-EDADGAPAP----AAGGSSAPSA
QSREGGTEQPRKEGAHHWSPWE---GTRRTG----RRKGRSRSIQAHGTLGQRPPVLSTS
GPIPESRQAVLQTSASAQGLAPQRAGSLLSLRTSAPSLHTQPPPVTGTDH-LSVRERAEA
LVRSSLGSSTSSTLSFLFGKRGFSSALVISGLSAADGGNTSDTQSSSSVNIVMGPSARAA
SQATR-------------------------------------------------------
------

------------------------------------------------------------
-------------------------MVSQVLQLLR-------QGVWAALTGGWYHDPEQS
KFTNSC--H-------LYLWLFLL-------LLP--------LALHLAFPPNAI----LV
FFYCSSVTIFFTIIKLVSYRLHLMFDKGEVIQQKPSRKEEKPSRDKEAK--GEHTTSHKN
PS--NNRQIHNGKKEEANRNLSTPPLRCSSRGQSITSHRSSG-PLELSAQETVEDLKGVI
LSEDHPIAP-VSSTSPGIKMKSLPASQAHMLETSPKSAIPVKPVATETFISVKRKERGS-
KGQ-PPLCHRSEGG-LVDKGPLKKLPHLSLSQYDLLETDVSFQPWGSENSVLI-LEPVSR
PQGSIREQVQSTSPQDSLSSS-CPQCDTVVAKPV-EEPVDTSCQVDTSCQVDTSCQADTS
CQADTSCQVDLPLNQELDSSDGEVAVTLIDTSQPGDPLSLHEPIKIVITMSSTPNS-MTD
LESPLHLKVVGTEKTCLKSGAEPTNQRVASSPNA-EQISIPVITLDLPEDGG--GGIPCP
EGQGSKRTPERLK-AKVSTNQCSG--YGSGEGESATKDHSSSS-REPWESASRLTPDIAS
E-------SKVGKEGQIILDPSSCKSSNEKRHARVLSVDSGTDVFLSKSSAEIIND-KEK
TMPTSKSDLEAKEGQIPNESNFLEFVSLLESINTSKVAASNQLNGSAEPNEESGLLR---
-------DNCSPEKKEEVLEKEKPSGHN-----SKQGKPDLQSQDHASTSPICTQPAKTT
AFFQGNRQRQIIYRVTSQQDSSVLQVISGPETSAQEEISVDAMHVFIDEH-GEIRSCYLK
SGNQKEGPLQPLPSNYDCLSQAREMQVSSSSTTTSESQDPSSGDPAVSALQQQLLLMVAR
RTQSETPRH-----------VSQDLEDSSGSSTRGKFNREQFYKFIIFPGKWVKVWYDRL
TLLALLD---RTEDVKENVLAILLIVLVSLLGFLTLSQGFCKDMWVLLFCLVMASCQYSL
LK-----------SVQPDPASPIHGHNQIITYSRPVYFCVLCGLILLLDTGAKARHPPSY
MVYGLKLFSPVFLQSARDYLIVFLYCFPAISLLGLFPQINTFCIYLLEQVDMLFFGGSAV
SGITSAV--YSVARSILAAALLHPVCFSAVK-EPWSTQHIPALFSAFCG-LLVALSYHLS
RQSSDPSVL-MSFMQCRLFPKFLHQNR---EESSADPLPKKMK--------DSVMDVLKW
DLIVCAVVAVLSFAVSASTVFLSLRPFLSIVLFALAGAVGFVT-HYLLPQLRKHHPWMWI
SHPILKNKEYHQRELRDVAHLMWFERLYVWLQCFEKYILYPALILNALTIDAFSISNHRR
LGTHWDIFLMITA--GMKLLRTSFCNPG--YQFINLSFTVIFFHFDYKDISESFLLDFFM
VSILFSK--LEDLLHKLQFVLTYVAPWQMAWGSSFHVFAQLFAIPH--------SAILFF
QTVATSIFSTPLSPFLGSVIFITSYVRPVKFWEKNYNTR---RMDNSNTRLAVQIERDPG
ND-DNNLNSIFYEHLTRTLQESLCGDLVLGRWGNYSSGDCFILASDDLNAFVHLIEIGNG
LVTFQLRGLEFR-GTYCQQREVEAIMEGDEEDRGCCFCKPGHLPHLLSCNAAFHLRWLTW
EITRTQYILEGYSILHNNAATMLQVFDLRRILIRYYIKSIIYYMVTSPKLLSWIKNESLL
KSLQPFAKWHYIERDLAIFNINTDDDYVPCLQGITRASFCNVYLEWIQHCARKRQEPSK-
S---L

PF05041 // ENSGT00390000013164_1_Domain_0 (1866, 2097)

DSDEDSPLVTLSFALCTLGRRALGTAAHNMAISLDSFLYGLHALFKGDFRVTARD
EWVFADMDLLHKVVAPAIR-----MSLKLHQDQFTCPDEYEDPVVLYEAIQSFEK-KVVI
CHEGDPAWRGAVLSNKEELLTLRHVVDEGADEYKVLMLHRSFLSFKVIKVNKECVRGLWA
GQQQELIFLRNRNPERGSIQNNKQVLRNLINSSCDQPLGYPMYVSPLTTSYLGTHRQLKN
VWGGPITLDRIRTWFWTKWVRMRKDCNARQ-HSGGNIEDV-DGGGVP---TTGGNNAPGG
GSQESSAEHPRKSGFQHGVSSC--EGTQRTG----RRKGRSQSVQAHSVLSQRPPMLSSS
GPNLESRQPFLQTSTSVHELAQRLSGSRLSLHTSATSLHSQPPPVTTTGH-LSVRERAEA
LIRSSLGSSTSSTLSFLFGKRSFSSALVISGLSAAEGGNTSDTQSSSSVNIVMGPSARAA
SQATRHLSE-PCEPTDTT-EQGQVRDPRLAEAVAE-TLRVVCRR-ASQEDMGLDDTASQQ
SASDEQ

------------------------------------------------------------
-------------------------MVSQVLQLLR-------QGVWAALTGGWYHDPEQS
KFTNSC--H-------LYLWLFLL-------LLP--------LTLHLAFPPNAI----TI
FIYCSSVTIFFTVIKLISYRLHLMFDEGEVVQQKSSLNAERQSKHKEAN--SENIIHHRV
PG--XXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXELPAQETVEDLKXXX
XXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--------------------
----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSSTPNS-MTE
LENSLHLKVIGTEKMGARSDAHPSVTDVTHPQNN-EQIRIPVITFELSEDGE--N-DAFP
EVSEREKTPERLM-VDISSNPCSG--YESGELDNAAKERNDTL-NGDSKTVPLVTSTLTC
K-------MEPDKEGQDSLDPSSCKTAHEKRPARVLSVDSGTDVLLSKTPTELPSD-KEK
TLPTSKSDLEAKEGQIPNESNFLEFVSLLESINTSKVMASNLSNGTTELIKEKGVIGD--
--------YYSQRR-WKVWGRVKVKVHN-----SKSGTPXXXXXXXXXXXXXXXXXXXXX
X-----------------------XXXXXXXXXXXXXXXXXXXXXXXXXX-XEIRSCYLK
SGNQKEGELLRQPSNCDCVSNARERHFSSSSTTTSASQEPSSGEPALSALQQQLLLMVAR
RTQSETPRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------XX-XXXXXXXX
X-XX--X---XXXXXXXXXXXXXX-XX--XXXXXXXXXXX-XX-------XXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXGHNQIITYSRPIYFCVLCGLILLLDIAAKARHPPSY
TVYGLRFFSSGSLQSVRDHLIVFLYCFPAISLLGLFPQINTFCIYLLEQIDMLIFGGSAA
AGTLSAI--YSISRSFVVALVLYAFCFTAVK-EPWSTQHIPALFSAFCG-LLVAVSYHLS
RQSSDPSVL-MSFIQCKLFPHFLHSNL---EEIPSDPLPKKMR--------DSVKEILKS
DLIVCTVVAILSFAVSASTVFLSLRPFLGLILFALACAVGFVT-HYMLPQLRKHHPWMWI
SHPILKNKEYHQREVKDVAHLMWFERLYVWLQCLEKYILYPAIILNALTIDAFSISNYRR
LGSXXXXXXXXX--XXXXXXXXXXXXXXXXXXXX----XXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXLEDLLHKLQFVMTYVAPWQLAWGSSFHVFAQLFAIPXXX------XXXXXX
XXXXXXXXXXXXX-----XXXXXXXXXXXXXXXXXXXXXXTRRVDNSNTRLAVQIEKDPV
ND-ERNSNSFPXXXXXXXXXXXXXXXXXXXXXXXXXXX-----------------XXXXX
X-----XX---X-XXX------XX-XXXXXXXX-------XX---------X-X------
------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSIIYFTVSSPKLLSWIKNESIL
KSLQPFAKWHYIERDLAMFSINIDDDYVPCLQGITRASYCNVYLEWIQYCARKRR

PF05041 // ENSGT00390000013164_1_Domain_0 (1856, 2098)

EPLQ-
G---LDSDEDSPLVTLSFALCIMGRRALGTASHNMAFSLDSFLYGLHALF-GDFRITSRD
EWVFADMDLLHKVVAPAXX-----XXXXXXXDQFTCLDEYEDPVVLYEAIQSFEK-KVVI
CHEGDPAWRSAVLSNKEELLTLRHVVDEGTDEYKVIMLHKSYLSFKVIKVNKECVRGLWA
GQQQELIFVRNRNPERGSIQNNKQVLRNLINSSCDQPLGYPMYVSPLTTSYLGTHSQMRN
VWGGPISLDNIKSWFLNKWLXXXXXXXXX-XXSGGNIEEMDSGGGTSA----GSSSNSSS
SSQENSVEHPRKEISQFRFSSQ--GGTYRPX----XXKGRSQSAQAHATFIQRPPISSLS
GPVLESHPSLLQTSTSVHEIAQRLSSSQLSLHNSTTSLHSQPHPVSTTGH-LNVRERAEA
LIRSSLGSSTSSTLSFLFGKRSFSSALVISGLSAADGGNTSDTLSSSSVNIAMGPSARAM
SQTTRQFSE-PCETTYAT-EQGRLHDQHLPQAMAE-SLSVICRR-ASQEDMGLDDTASQQ
SLSEES

------------------------------------------------------------
-------------------------MVSQVLQLLR-------QGVWAALTGGWYHDPEQS
KFTNSC--H-------LYLWLFLL-------LLP--------LALHLAFPPNAI----LV
FFYCSSVTILFTIIKLVSYRLHLMFDKGEVIQQKPSRKEEKPSRDKEAK--GEHTTSHKN
PS--NNRQIHNGKKEEASRNLSTPPLRCSSRGQSITSHRSSG-PLELSAQETVEDLKGVI
LSEDHPIAP-VSSTSPGIKMESLPASQAQMLETTPKSAIPIKPVATETFISGKGKERGS-
KGQ-PPLRHRSEGG-LVDKGPLKKLPHLSLSQYDLLETDVSFQPWGSENSVLI-LEPVSC
PQGSIRERVQSTSPQDSLSSS-CPQCDTIVAKPV-EEPVDTSCQVDT-------------
-----FCQVDLPLNQEVDSSDGEVAVTLIDNSQPGDPLSLHEPIKIVITMSSTPNS-MTD
LESSLHLKVVGTEKTGLKSGVESANQRAASSPNA-EQISIPVITLDLPEDGG--GSIPCP
EGKGSKRTPERLK-ARVSTNQCSG--YESGEGENATKDHSSSS-REPWESASRLLPGIAS
E-------SKVGKEGQINLDPSSCKSSNEKRHARVLSVDSGTDVFLSKSSAEIISD-KEK
TMPTSKSDLEAKEGQIPNESNFLEFVSLLESINTSKVAASNQLNGSAEPNEESGLLQ---
-------DNCSQEKKEETLENEKPSGHN-----SKQGKPDLQSQDHTSTSPVCTQPAKTT
AFFQGNRQRQIIYRVTSQQDSSVLQVISGPETSVQEEISVDAMHVFIDEH-GEVRSCYLK
SGNQKEGPLQPLPSNYDCLSQTREMQVSSSSTTTSESQDPSSGDPAVRALQQQLLLMVAR
RTQSETPRH-----------VSQDLEDSSCSSTQGKFNREQFYKFIIFPGKWIKVWYDRL
TLLALLD---RTEDVKENVLAVLLIVLVSLLGFLTLSQGFCKDMWVLLFCLVMASCQYSL
LK-----------SVQPDPASPIHGHNQIITYSRPIYFCVLCGLILLLDTGAKARHPPRY
VVYGLKLFSPVFLQSARDFLIVFLYCFPAISLLGLFPQINTFCIYLLEQVDMLFFGGSAV
SGITSAV--YSVARSILAAALLHPVCFSAVK-EPWSMQHIPALFSAFCG-LLVALSYHLS
RQSSDPSVL-MSFMQCKLFPKFLHQNL---EESSADPLPKKMK--------DSVTDVLKW
DLIVCAVVAVLSFAVSASTVFLSLRPFLSIVLFALAGAVGFVT-HYLLPQLRKHHPWMWI
SHPILKNKEYHQRELRDVAHLMWFERLYVWLQCFEKYILYPALILNALTIDAFSISNHRR
LGTHWDIFLMITA--GMKLLRTSFCNPS--YQFINLSFTVIFFHFDYKDISESFLLDFFM
VSILFSK--LGDLLHKLQFVLTYVAPWQMAWGSSFHVFAQLFAIPH--------SAMLFF
QTIATSIFSTPLSPFLGSVIFITSYVRPVKFWEKNYNTR---RVDNSNTRLAVQIERDPG
ND-DNNLNSIFYEHLTRTLQESLCGDLLLGRWGNYSSGDCFILASDDLNAFVHLIEIGNG
LVTFQLRGLEFR-GTYCQQREVEAIMESDEEDRGCCCCKPGHLPHLLSCNAAFHLRWLTW
EITRTQYILEGYSILDNNAATMLQVFDLRRILIRYYIKSIIYYMATSPKLLSWIKNESLL
KSLQPFAKWHYIERDLAIFSINTDDDYVPCLQGITRASFCNVYLEWIQHCARKRQEPSK-
T---L

PF05041 // ENSGT00390000013164_1_Domain_0 (1866, 2097)

DSDEDSPLVTLSFALCTLGRRALGTAAHNMAISLDSFLYGLHALFKGDFRVTARD
EWVFADMDLLHKVVAPAIR-----MSLKLHQDQFTCPDEYEDPAVLYEAIQSFEK-KVVI
CHEGDPAWRGAVLSNKEELLTLRHVVDEGADEYKVLMLHRSFLSFKVIKVNKECVRGLWA
GQQQELIFLRNRNPERGSIQNNKQVLRNLINSSCDQPLGYPMYVSPLTTSYLGTHRQLKN
VWGGPITLDRIRTWFWTKWVRMRKDCNAGQ-HSGGNIEDV-DGGGVP---ATGGNNAPSG
GSQESSAEQPRKGGFQHGVSSC--EGTQRTG----RRKGRSQSMQAHSALSQRPPMLSSS
GPILESRQPFLQTSTSVHELAQRLSGSRLSLHTSATSLHSQPPPVTTTGH-LSVRERAEA
LIRSSLGSSTSSTLSFLFGKRSFSSALVISGLSAAEGGNTSDTQSSSSVNIVMGPSARAA
SQATRHLSE-PCEPTDTT-EQGQVRDRRLAEAVAE-TLRVVCRR-ASQEDMGLDDTASQQ
SASDEQ

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------LNALTIDAFSISNYRR
LGTHWDIFLMII--AGMKLLRTSFCNPT--QQFIHLTFTVMFFHFDFKDISESFLLDFFV
VSILFSKAIIGDLLHKLQFVMTYVAPWQMAWGSSFHVFAQLFAIPXXX------XXXXXX
XXXXXXXXXXXXXXX-----XXXXXXXXXXXXXXXXXXXXTRRVDNSNTRLVVQIEKDPG
ND-DNNLNSIFYEHLTRALQESLCGDLILGRWGNYSSGDCFILASDYLNAFVHLIEIGNG
LVTFQLRGLEFR-GTYCQQREVEAIMEGDEDDRGCCCCKPGHLPHLLSCNAAFNLRWLTW
EITRTQYILEGYSIIDNNAATMLQIFDLRRILIRYYIKSMIYYMVASPKLYSWVKNESLL
KSLQPFAKWHYIERDLTIFNINIDDDYVPCLQGITRASYCNVYLEWIQYCAQKRQ

PF05041 // ENSGT00390000013164_1_Domain_0 (1856, 2098)

EPAK-
N---LDSDEDSILVTLSFALCILGRRALGTAAHNMAIXXXXXXXXXXXXXXXXXXXXXXX
XXX-----XXXXXXXXXXXXXXXXXXXXXXXDQFTCPDEYEDPVVLYEAIQSFEK-KVVI
CHEGDPAWRGAVLSNKEELLTLRHVVDEGTDEYKVIMLHRSFLSFKVIKVNKECVRGLWA
GQQQELIFLRNRNPERGSIQNNKQVLRNLINSSCDQPLGYPMYVSPLTTSYLGTHRQLKN
VWCGPVTFDRIRIWFRMKWLRMRKDCDAG-QHSASNIEDIDEGGTLPM----GSNNGPRG
ESQESSTEQPRKDGTYHY------EGTQRTG----RKKGRSQSVQAHGPLCQRPPILSSS
GPILESHQAFLQTSTSVHELAQRLSGSRLSLHTSDASLHSQPPPVTTTGH-LSVREQAEA
LIRSSLGSSTSSTLSFLFGKRSFSSALVISGLSAAEGGNTSDTQSSSSVNIVMGPSARAA
SQATRHFSE-PCEPTEATIEQEHLRDHRLTEAMPG-NVGVICRR-ASQEDMGLDDTASQQ
SASDEQ

------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------MI----TA
LFYCSSVTVLFTIIKVVSYRLHLMFDKGEVIQQRSPRKMEKPKKDREAN--SEHATNPKH
LS--NTRPIHSSKKEEMGGGVPTPPLHCSSHGQSLSSHRSSG-PLELPVQETVEDLKGVI
LSKDHPGAP-MSSTSPGIKTESLPASQVCLPEPMPRSAGLTNPAVPEALINEQRRGREG-
QGQ-CPPCHRSEGG-LVDREDLKKLPRLSLSQYDLLETDVSFQPWGSENSVLI-PEPVTC
PQGSIREQLQSRSPQDSLSNS-CPQCHTVMAKPA-ERLAG--------------------
----TSSQVDLPFSQGINSSDSEVTVTLIDTSQPGDPLSLHEPIKIVITMSS--NS-MTE
EGSCLHLKVTGTEQVGPRSHMEPASPRGASPPKA-EHIQIPVITLELSEDGG--GGVTGP
EGHGSQRSPDRLRVE--ASDQCSS-----EEAGRATEACSPGP-RHAREPAQASTPPLAS
E-------AEGEGDSQASLDPASDKGSHEKRHARVLSVDSGTHVFLSRSSMDVVSD-KEK
TIPTSKSDLEAKEGQIPNESNFLEFVSLLESINTSKVVTSTQLKGSADQHGTSE------
-ARGLHGDHYSQGKKEEILEKKTLSGED-----SKPEKSDLQSQDHAGTSPVFTPPAKAA
ALFQGNRQRQIIYRVTSQQDSSVLQVISGPETSVQEEISVDAMHVFIDEH-GEIRSCYLK
SGNQKEGSFQHPVSNEDCASQAREVHLSSSSTSTCESPDPSSGDPAVSALQQQLLLMVAR
RTRSEIPR-----------LVSQDLEDSSCSSAPGKFNREQFYKFIIFPGKWIKVWYDRL
TLLALLD---RTEDVKENVLAIVLSVLVSLLGFLTLNRGFCRDLWVLLFCVVMASCQYSL
LK-----------SVQPDPASPIHGHNQIITYSRPIYFCVLCGLVLLLDGEAKSRHPPHY
IVYGLKLFSPESLQTARDYLIVFLYCFPAISLLGLFPQINTFCTYLLEQIDMLLFGGSAV
SGILSAL--YSVGRSILAAALLHVLCFSAVK-EPWSTQHIPALFSAFCG-LLVASSYHLS
RQSSDPSVL-LSFFQCRFFPKFLHPSL---EESSTDPLPQKMK--------DSVKDVLRS
DLVVCSVVAVLSFAVSASTVFLSLRPFLSVVLFALAGAVGLIT-HHLLPQLRKHHPWMWV
SHPVLKNKEYKQREVRDVAHLMWFERLYVWLQCFEKYILYPAIILNALTIDAFSISNYRR
LGTHWDIFLMII--AGMKLLRTSFCNPV--HQFINLSFTVIFFHFDYKDFSESFLLDFFM
VSILFSK--LGDLLHKLQFVLAYVAPWQMAWGSSFHVFAQLFAIPHSA--------VLFF
QTVATAVFSTPLSPFLGSVIFITSYARPVKFWEKNYNTR---RVDNSNTRLAVQIEKDPG
GD-DNNLNSIFYEHLTRTLQESLCGDLVLGRWGNYSSGDCFILASDDLNAFVHLIEIGNG
LVTFQLRGLEFR-GTYCQQREVEAIMEGDEEDRGCCCCQPGHLPHLLSCNAAFRLRWLTW
EVARTQYILEGYSIIDNNAATMLQVFDLRRVLIQYYIKSIIYYMVASPKLLSWVKNDSLL
KSLQPFAKWHHIERDLAMFNINIDDDYVPCLQGITRASYCNVYLEWIQYCAGKRQEPSK-
T---L

PF05041 // ENSGT00390000013164_1_Domain_0 (1866, 2097)

DSDEDSPLVTLSFALCILGRRALGTAAHNMAMSLDSFLYGLHALFKGDFRITVRD
EWVFADMDLLHKVVVPAIR-----MSLKLHQDQFTCPDEYEDPAVLYGAIQSFEQ-KVVI
CHEADPAWRGAVLSNREELLTLRHVVDEGTDEYKVIMLHRGFLSFKVIKVNKECVRGLWA
GQQQELIFLRNRNPERGSIQNNKQVLRNLINSSCDQPLGYPMYVSPLTTSYLGTHRQLRN
VWGRPVMLDSLRTWFQARWLSMRKDCNTG-QRSGGAIEDLDGGGAPSG------------
---DSSLEQPQKGGTQPWVSPCK--GAQRTG----HRKGRSQSVQVPSALSQRLPVLSSS
GPIVESRQAFLQTSTSVHELAPRPSGSRLSLHTSTTSLHSQPPPGTTTGH-LSVRERAEA
LIRSSLGSSTSSTLSFLFGKRSFSSALVISGLSAAEGGNTSDTQSSSSVNIVMGPSARAA
GHATRHFSE-PCDPTEAA-EQGQLRDRRLAEAVAE-NLRVMCRR-ASQEDMGLDDTASQQ
SASDEQ

------------------------------------------------------------
-------MLTGILPSTALYRCSCLVLHLCAFQVPRPQPPDKIQNAQEQLPGA-DL-PPES
ALSSQV--TVAMINTLLSLLICTH-------TPC--------PSLHLAFPPNAI----TA
FFYCSSVTVFFTIIKLVSYRLHLMFDKGEVIQQRPSRKKEKLNKDKEAN--KEHITNHKI
PS--NNRQINNGKKEEPHRNLSTPPLRCSSRGQSLNSHHSSG-PLELPAQETVEDLKGVI
LSEDQAVAP-VSSTSPGIKRESLPACEEDVPETTTTPAVPMKPVVAETRISGKGKERGG-
KGQ-PPFRHRSEGG-LVEKEALKKLPHLSLSQYDLLETDVSFQPWGSENSVLS-PEPVIY
AQGSLRERLQSQSPPDSLSSS-CPQCNTVIARPV-HEPLD--------------------
----ASRQVDPTMNQEVDYSDSEVAVTLIDTSQPGDPLSLHEPIKIVITMSSTPNS-MTD
LESSLHLKVIGTERAGLKSDAEPAALEVASPPNT-EQMRIPVITLELSEDGG--GGAMCP
EGNGSDRTPERLM-VEASSNQCSG--YESGEGGHATKDGSPSP-GDCCETTSPFTPQVVP
E-------SEGVRDSQANLDPSSCKTSHEKRHTRVLSVDSGTDVFLSKSSTEVIND-KEK
TMPTSKSDLEAKEGQIPNESNFLEFVSLLESINTSKLAASNQRNGSAEQNKDSGLLG---
-------DNCSHEKKEEIQESEKPNGHN-----SKHGKPDMQSQDHTSTSPVLTEPAKIT
TLFQGNRQRQIIYRVTSQQDSSVLQVISGPETSVQDEMSVDAMHVFIDEH-GEIRSCYLK
SGNQKEGPLQHQPSNYDSFSHAREIQISSSSTTTSESQDPSSGDPAVSALQQQLLLMVAR
RTQSETPR-----------HLSQDLEDSSCSSTQGKFNREQFYKFIIFPGKWIKVWYDRL
TLLALLD---RTEDVKENVLAVLLIVLVSLLGFLTLNQGFCKDVWVLLFCLVMASCQYSL
LK-----------SVQPDPASPIHGHNQIITYSRPIYFCVLCGLILLLNTGAKARHPPTY
IVYGLKLFSPRSLQSARDLLIVFLYCFPAISLLGLFPQIDTFCIYLLEQIDMLFFGGSAV
SGMTSAI--YSVARSATATALLHVFCFSAVK-EPWSTQHIPALFSAFCG-LLVALSYHLS
RQSSDPSVL-LSFIHCRLLPKFLHQNL---EELAADPLPKKMK--------DSVKDILKS
DLVICSVAAVLSFAISASTVFLSLRPFLSVVLFALAGSVGLVT-HYMLPQLRKHHPWMWI
SHPVLKNKEYQQREVRDVAHLMWFERLYVWLQCFEKYILYPAIILNALTIDAFSISNYRR
LGTHWDILLMVV--AGMKLLRTSFCNP-A-HQFIHLGFTVIFFHFDYKDISESFLLDFFM
VSILFSK--LGDLLHKLQFVMTYVAPWQMAWGSSFHVFAQLFAVPHSA--------MLFF
QTIVTSIFSTPLSPFLGSVIFITSYVRPVKFWEKSYNTR---RVDNSNTRLVVQIEKDPG
ND-DNNLNSIFYEHLTRALQESLCGDLVLGRWGNYSSGDCFILASDYLNAFVHLIEIGNG
LVTFQLRGLEFR-GTYCQQREVEAIMEGDEEDRGCCCCKPGHLPHLLSCNAAFHLRWLTW
EITRTQYILEGYSIIDNNAATMLQVFDLRRILIRYYIKSIIYYMVTSPKLLSWIKNESLL
KSLQPFAKWHYIERDLAMFNINIDDDYVPCLQGITRASYCNVYLEWIQYCARKRQEPSK-
N---L

PF05041 // ENSGT00390000013164_1_Domain_0 (1866, 2098)

DSDEDSPLVTLSFALCILGRRALGTAAHNMALSLDSFLYGLHALFKGDFRITARD
EWVFADMDLLHKVVAPAIR-----MSLKLHQDQFTCPDEYEDPGVLYEAIQSFEK-KVVI
CHEGDPAWRGAVLSNKEELLTLRHVVDEGADEYKVIMLHRSFLSFKVIKVNKECVRGLWA
GQQQELIFLRNRNPERGSIQNNKQVLRNLINSSCDQPLGYPMYVSPLTTSYLGTHRQLQS
VWSGPVTLDSIRTWFRTKWLRVRKGCDSG-QHGAGHIEDVDRRSAP----SAGGGQAPSG
ESQESSTEQPRKDATHHWSPHE---GTQRTG----RRKGRSQSVQAHGALSQRPAVLSSS
GPNLESHQAFLQTSTSVHELAQRLSGSRLSLHTSAASLHSQPPPVTTTGH-LSVRERAEA
LIRSSLGSSTSSTLSFLFGKRSFSSALVISGLSAAEGGNTSDTQSSSSVNIVMGPSARAT
SQATRHFSE-PCEPTEAT-ELGQLRD-GLAEAAAE-NGGLLCRR-ASQEDMGLDDTASQQ
SASDEL

------------------------------------------------------------
-------------------------------QLLR-------QGVWAALTGGWYHDPEQS
KFTNSC--H-------LYLWLFLL-------LLP--------LALHLAFPPTVI----TA
LFYCSSVTVLFVVIKVVSYRLHLMFDEGEVIQQRSPRKMGKPKKDREAN--SEHATNPRN
LS--NTRPIHSSKKEEMVGSVSTPPLRCSSRGQSLSSHRSSG-TLELPAQETVENLKGVI
LSEDHPGAP-MSSTSPGIKMESLPASHVCLPEPVPRSAGLTNPAVPEALINEERRGREG-
QGQ-CPPRHRSEGG-LVDKGDLKKLPRLSLSQYDLIEADVSFQPWGSENSVLI-PEPVTC
PQGSIREHLQSKSPQDSLSSS-CPQCHTIMAKPA-ERLAG--------------------
----TLGQVDLPFSQGMNSSDSEVAVTLIDTSQPGDPLSLHEPIKIVITMSSTPNS-TTE
EGSSLHLKVTGTEQVGSRSHVDPASPRVASPPNA-EHIQIPVITLELS-DGG--GGVTGP
EGHGNQRTPDRLRVE--ASDQCSS-----EKVGRTTQTHSPGP-RHAREPA------LTS
E-------AKGEKDGQDTLDPSSCKGSHEKRHARVLSVDSGTNVFLGRSSTDVVSD-KEK
TLPTSKSDLEAKEGQIPNESNFLEFVSLLESISTSKVVASTQPKGSQ-------------
----CFSDHYSQGKKEEILEKKKFSGQD-----SKPEKPGLQSQDHAGASPVFTPPAKTT
TLFQGNRQRQIIYRVTSQQDSSVLQVISGPEASVQEEISVDAMHVFIDEH-GEIKSCYLK
SGNQKEGSLQHPLSNEDCASQAREVHLSSSSTTTCESPDPTSGDPAVSALQQQLLLMVAR
RTHSETPR-----------CVSQDLEDSSCSSAPGKFNREQFYKFIIFPGKWIKVWYDRL
TLLALLD---RTEDVRENVLAVVLSILVSLLGFLTLNRGFCRDLWVLLFCVVMASCQYSL
LK-----------A-RPHPALTLPGHNQIITYSRPIYFCVLCGLVLLLDAGAKSRHPPRY
VVYGLKLFSPESLQTARDHLIVFLYCFPAISLLGLFPQINTFCTYLLEQIDILLFGGSGM
CGRSIES-----------QASDSGCLLLFPQ-EPWSTQHIPALFSAFCG-LLVALSYHLS
RQSSDPSVL-LSFIQCRFFPKFLHQSL---EESATDPLPQKMK--------DLVKDVLRS
DLVICSVVAVLSFAVSASTVFLSLRPFLSVVLFALAGAVGLIT-HHLLPQLRKHHPWMWV
SHPVLKGREYHQREVGDVTHLMWFERLYVWLQCFEKYILYPAIILNALTIDAFSISNYRR
LGTHWDIFLMII--AGMKLLRTSFCNPV--HQFINLSFTVIFFHFDYKDLSESFLLDFFM
VSILFSK--LGDLLHKLQFVLAYVAPWQMAWGSSFHVFAQLFAIPHIL--------S--T
STVATAVFSTPLSPFLGSVIFITSYARPVKFWEKNYNTR---RVDNSNTRLAVQIERDAG
GD-DNNLNSIFYEHLTRTLQESLCGDLVLGRWGNYSSGDCFILASDDLNAFVHLIEIGNG
LVTFQLRGLEFR-GTYCQQREVEAIMEGDEEDRGCCCCQPGHLPHLLSCNAAFHLRWLTW
EVTRTQYILEGYSIIDNNAATMLQVFDLRRVLIRYYIKSIIYYMVTSPKLLSWVKNESLL
KSLQPFAKWHHIECDLAMFNINIDDDYVPCLQGITRASYCNVYLEWIQYCAGKRQEPSK-
T---L

PF05041 // ENSGT00390000013164_1_Domain_0 (1866, 2097)

DSDEDSALVTLSFALCILGRRALGTAAHNMAMSLDSFLHGLHALFKGDFRITAQD
EWVFADMDLLHKVVAPAIR-----MSLKLHQDQFTCPDEYEDPAVLYGAIQSFEQ-KVVI
CHEADPAWRGAVLSNREELLTLRHVVDEGTDEYKVIMLHRGFLSFKVIKVNKECVRGLWA
GQQQELIFLRNRNPERGSIQNNKQVLRNLINSSCDQPLGYPMYVSPLTTSYLGTHRQLRN
VWGGPVTLDRLRTWFRARWMSMRKDCNTG-QRSGGATEDLDGGGAPSG------------
---DSSTEQPQKGCTQPWASPRE--GAQRTG----HRKGRSQSGQAPSALSQRPPTLSSS
GPIVESRQAFLQTSTSVHELAPRPSGSRLSLHTSATSLHSQPPPVTTTGH-LSVRERAEA
LIRSSLGSSTSSTLSFLFGKRSFSSALVISGLSAAEGGNTSDTQSSSSVNIVMGPSARAA
GHTTWHFSE-PCDPTEAA---------------AE-NRRVTCRR-ASQEDMGLDDTASQQ
SASDEQ

------------------------------------------------------------
-------------------------MVSQVLQLLR-------QGVWAALTGGWYHDPEQS
KFTNSC--H-------LYLWLFLL-------LLP--------LALHLAFPPNAI----IV
FFYCSAVTIFFTIIKLVSYRLHLMFDKGEVIQQKPSRKEEKPNKDKEAK--GEHITNPKN
PS--NNRQIHNGKKEEASRNLSTPPLRCSSRGQSITSHHSSG-PLELSAQETVEDLKGVI
LSEDHPIAP-VSSTSPGIKMESLPACQAHMLETMSKSAIPVKPIATETLINGKGKERGG-
KGQ-PPLRHRSEGG-LVDKGPLKKLPHLSLSQYDLLETDISFQPWGSENSVLI-PEPVSC
PQGSVRERVQSKSPQDSLSSS-CPQCDTIVAKPV-EEPADTSCQVD--------------
----TSCQVDLPLNQEVDSSDSEVAVTLIDTSQPGDPLSLHEPIKIVITMSSTPNS-MTD
LESSLHLKVVGIEKTGVKSDAEPTNPGAASSPNA-EQISIPVITLDLPEGGG--GGVPCP
EGNGSERTPERLK-ARVSTNQCSG--YGSGEGGSATKDHSSSS-REPWESASRLTPDTAS
E-------SKVGKEGLTNLDPLSCKSSHEKRHARVLSVDSGTDVFLSKSSAEIVND-TEK
TMPTSKSDLEAKEGQIPNESNFLEFVSLLESINTSKMAASNQLNGSAEQNEESGLLQ---
-------DNTSQEKKEEILENEKPSGHS-----PKQGKPDLQSQDHTSTSPACTQPAKTT
AFFQGNRQRQIIYRVTSQQDSSVLQVISGPETSVQEEISVDAMHVFIDEH-GEIRSCYLK
SGNQKEGPLQPLPSNCDCLSQAREMQVSSSSTTTSESQDPSSGDPAVSALQQQLLLMVAR
RTQSETPRH-----------VSQDLEASSCSSTQGKFNREQFYKFIIFPGKWIKVWYDRL
TLLALLD---RTEDIKENVLAILLIVLVSLLGFLTLSQGFCKDMWVLLFCLVMASCQYSL
LK-----------SVQPDPASPIHGHNQIITYSRPIYFCVLCGLILLLDTGAKARHPPSY
IVYGLKLFSPVFLQSARDYLIVFLYCFPAISLLGLFPQINTFCIYLLEQIDMLFFGGSAV
SGITSAV--YSVARSFLAAALLHAVCFSAVK-EPWSTQHIPALFSAFCG-LLVALSYHLS
RQSSDPSVL-MSFIQCRLLPKFLHQNL---EESAADPLPKKMK--------DSVMDVLKW
DLIVCAVVAVLSFAVSASTVFLSLRPFLSIVLFALAGAVGFVT-HYLLPQLRKHHPWMWI
SHPILKNKEYHQREVRDVTHLMWFERLYVWLQCFEKYILYPALILNALTIDAFLISNHRR
LGTHWDIFLMIIA--GMKLLRTSFCNPV--YQFINLSFTVIFFHFDYKDISESFLLDFYM
VSILFSK--LGDLLHKLQFVLTYVAPWQMAWGSSFHVFAQLFAIPH--------SAVLFF
QTIATSIFSTPLSPFLGSVIFITSYVRPVKFWEKNYNTR---RVDNSNTRLAVQIERDPG
ND-DNNLNSIFYEHLTRTLQESLCGDLVLGRWGNYSSGDCFILASDDLNAFVHLIEIGNG
LVTFQLRGLEFR-GTYCQQREVEAIMEGDEDDRGCCCCKPGHLPHLLSCNAAFHLRWLTW
EITRTQYILEGYSILDNNAATMLQVFDLRRILIRYYIKSIIYYMVTSPKLLSWIKNESLL
KSLQPFAKWHYIERDLAMFNINIDDDYVPCLQGITRASFCNVYLEWIQHCARKTQEPSK-
T---L

PF05041 // ENSGT00390000013164_1_Domain_0 (1866, 2097)

DSDEDSPLVTLSFALCTLGRRALGTAAHNMAISLDSFLYGLHALFKGDFRITARD
EWVFADMDLLHKVVAPAIR-----MSLKLHQDQFTCPDEYEDPAVLYEAIQSFEK-KVVI
CHEGDPAWRGAVLSNKEELLTLRHVVDEGADEYKVIMLHRSFLSFKVIKVNKECVRGLWA
GQQQELIFLRNRNPERGSIQNNKQVLRNLINSSCDQPLGYPMYVSPLTTSYLGTHKQLKN
VWGGPITLDRIRTWFWTKWVRMRKDCNARQ-QSGGNIEDV-DGGGAP---ATGGNNAPSG
GSQESSAEQPRKGGAQHGVSSC--EGTQRTG----RRKGRSQSVQAHSALSQRPPMLSSS
GPILESRQTFLQTSTSVHELAQRLSESRLSLHTSATSLHSQPPPVTTTGH-LSVRERAEA
LIRSSLGSSTSSTLSFLFGKRSFSSALVISGLSAAEGGNTSDTQSSSSVNIVMGPSARAA
SQATRHLSE-PCEPTDAT-EQGQLRDRRPAEAVAE-TLGVVCRR-ASQEDMGLDDTASQQ
SVSDEQ

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------ELPAQETVEDLKXXX
XXXXXXXAP-LSSTSPCIKTENLPVSKMSMPETVTNSAILMKPVTMETLINNKVKEREG-
KMQ-PPFRHRSEGG-LVDKGNLKKLSHLSLSQYDLLETDVSFQPWGSENTVLI-PDPVNY
PKGSIREQLQSKSPQDSLSSS-CAQCNTSIVRQA-EAPMD--------------------
----TSCQLDPPFNEEVDYSDSEVAVTLIDTSQPGDPLSLHEPIKIVITMSSTPNS-MSD
LESSLHLKVVGTERTSSKSEAEPATPEVTSPPNI-EQMRIPVITLELSEDGG--GGIICP
EGNGSERTPERLM-VETSSSQCSA--YESGEGGNATKDCNPSP-RNHCETATLLTTHLAS
E-------SEGGKEGHAKLDPSSCKISHEKRHARVLSMDSGTDVFLGKSSTEIIND-KEK
TIPTSKSDLEAKEGQMPNESNFLEFVSMLESINTSKVVASNQSNGSAEPRNESGLLG---
-------DNCTQEKKEEIMESEKRNGCN-----SKQGKPDIQSQDHTSNSPAFTEPAKIT
TLFQGNRQRQIIYRVTSQQDSSVLQVISGPETSVQDEISVDAMHVFIDEL-GEIRSCYLK
SGNQKEGPLQHQPSNYDCFPNAREVQISPSNTTTSESQDQSSGDPTVSALQQQLLLMLAQ
RTQSETPRH-----------LSQDLENSSSSSTQGKFNREQFYKFIIFPGKWIKVWYDRL
TLLALLD---RXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXX
XXX----------SVQPDPASPIHGHNQIITYSRPIYFCVLCGLILLLDAGAKARRPPTY
VVYGLKLFSPGCLQSARDHLIVFLYCFPAITLLGLFPQINTFCIYLLEQIDMLLFGGSAV
SGIISAI--YSVARSFTAAAVLHVFCFSAVK-EPWSTQHIPALFSAFCG-LLVALSYHLS
RQSSDPSVL-MSYFQCRLFPKFLHENL---EDWTADPLPKKMK--------DSVKDSLKS
DLIFCTVAAVLSFAVSASTVFLSLRPFLSIVLFALAGAVGFIT-HYMLPQLRKHHPWMWI
SHPILKNKEYQQREVTDIAHLMWFERLYVWLQCFEKYILYPAIILNALTIDAFSISNYRR
LGTHWDIFLMVV--AGMKLLRTSFCNPV--HQFITLSFTVIFFHFDYKDISESFLLDFFV
VSILFSK--LGDLLHKLQFVMTYVAPWQMAWGSSFHVFAQLFAIPH--------SAMLFF
QTIATAVFSTPLSPFLGSVIFITSYVRPVKFWEKNYNTR---RVDNSNTRLAVQIEKDPX
XX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXX-XTYCQQREVEAIMEGDEDDRGCCCCQPGHLPHLLSCNAAFNLRWLTW
EITRTQYILEGYSILDNNAATMLQVFDLRRILIRYYIKSIIYYMVTSPKLLSWIKNESLL
KSLQPFAKWHYIERDLAMFNINTDDDYVPCLQGITRASYCNVYLEWIQYCAQKRQ

PF05041 // ENSGT00390000013164_1_Domain_1 (1856, 1951)

EPST-
T---LDSDEDSPLVTLSFALCILARRALGTAAHNMAISLDSFLYGLHALFKGDFRITAQD
EWVFADMDLLHKVVAPAIR-----MSLKLHQXXXXXXXXXXXXXXXXXXXXXXXX-XXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXX-XXXXXX---XXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXRRKGRGRSQSVQAHAALSQRPPVSSLS
GPVLESHQAFLQTSTSVHELSQRLSGSQLSLHNSVTSLHSQPPPVITTGH-LSVRERAEA
LIRSSLGSSTSSTLSFLFGKRSFSSALVISGLSAAEGGNTSDTQSSSSVNIVMGPSXXXX
XXXXXHFSE-PCEPTDAT-EQSQLHDRCLAEAMAAGSLGVTCRR-ASQEDMGLDDTASQQ
SASDEQ

------------------------------------------------------------
-------MV------------------SQGLQLLRQ-------GVWAALTGGWYHDPEQS
KFTNSC--H-------LYLWLFLL-------LLP--------LALHLAFPPNAI----TV
FFYCSSVTLFFTIIKLVSYRLHLMFDEGEVIQHRTSRKNEKSNKDKEAN--SEHIIYHKN
PS--NNSRINNGKKEEDNRNVSTPPLLCSSRGQSITSHHSSG-LLELPAQETVEDLKGVI
LSEDQPLAP-LSSTSPCSKIENLPTSKVYLPETMTTSAILMKPVAMETLINNKGKERGG-
RVQ-PPFRHRSEGG-LVDKETLKKLPHLSLSQYDLLQTDVSVQPWGSENSVLI-PDPINH
PKGCLQEPLQSRSPQDSLSSS-CPQCNTIIARPA-EELLD--------------------
----TSCQVDLPFNQEANCSDSEVAVTLIDTSQPGDPLSLHEPIKIVITMSSTPNS-MTD
LESSLHLTVIGTERTSSKSEAQPA-----APPDK-EQIKIPVITLEVSEDGR--GSTICP
EGNGSERTPERLM-VEASSNQCSG--YESGEGAPVSKDCSLSP-KSHHETATPLLPHVAS
E-------SEGAKEGQTNLDPSSCKASHEKRHARVLSVDSGTDVFLGKSSTEIILD-KEK
TIPTSKSDLEAKEGQMPNESNFLEFVSLLESINTSKVVASNQSNGSGEPTKESGLLG---
-------DNCTQEKKEETMESEKHNGCN-----SKQGKPNIQSQDHTSNSPVFTEPAKIT
TLFQGNRQRQIIYRVTSQQDSSVLQVISGPETSVQDEISVDAMHVFIDEH-GEIRSCYLK
SGNQKEGPLQHQPSNYDGFSNAGEVQISSSTTTTSESQEPSSGDAAVSALQQQLLLMVAR
RTQSETPR-----------HLSQDMEDSSCSSTQGKFNREQFYKFIIFPGKWIKVWYDRL
TLMALLD---RTEDVKENVLAILLIVLVSLLGFLTLNRGFCKDLWVLLFCLVMASCQYSL
LK-----------SIQPDPASPIHGHNQIITYSRPIYFCVLCGLILLLDTGAKARRPPTY
VVYGLKLFSPGSLQTARDHLVVFLYCFPAITLLGLFPQINTFCIYLLEQIDMLAFGGSAV
SGIISAL--YSVARSLAAASVLHVFCFSAVK-EPWSLQHIPALFSAFCG-LLVAFSYHLS
RQSSDPSVL-MSYIQCKLFPKLLHQNL---EESATDPLPKKMK--------DSVKDSLKS
DLIFCTVAAVLSFAVSASTVFLSLRPFLSIVLFALAGTVGLLT-HYVLPQLRKHHPWMWL
SHPILKNKEYQQREVRDIAHLMWFERLYVWLQCFEKYILYPTIILNALTIDAFSISNYRR
LGTHWDIFLMVI--AGMKLLRTSFCNP-V-HQFVTLSFTVIFFHFDYKNISESFLLDFFM
VSILFSK--LGDLLHKLQFVMTYVAPWQMAWGSSFHVFAQLFAIPHSA--------MLFF
QTIATSIFSTPLSPFLGSVIFITSYVRPVKFWEKNYNTR---RVDNSNTRLSVQIEKDPG
ND-DNNLNSIFYEHLTRALQESLCGDLVLGRWGNYSSGDCFILASDYLNAFVHLIEIGNG
LVTFQLRGLEFR-GTYCQQREVEAIMEGDEDDRGCCCCKPGHLPHLLSCNAAFNLRWLTW
EIIRTQYILEGYSILDNNAATMLQVFDLRRILIRYYVKSIIYFMITSPKLLSWIKNESLL
KSLQPFAKWHYIERDLAMFNINIDDDYVPCLQGITRASYCNVYLEWIQYCARKRQEPSK-
N---L

PF05041 // ENSGT00390000013164_1_Domain_0 (1866, 2098)

DSDEDSPLVTLSFALCILGRRALGTAAHNMAMSLDSFLYGLHALFKGDFRVTAQD
EWVFADMDLLHKVVAPAIR-----MSLKLHQDQFTCPDEYEDPVVLYETIQSFEE-KVVI
CHEGDPTWRNSVLSNKEELLTLRHVVDEGTDEYKVIMLHKSFLSFKVIKVNKECVRGLWA
GQQQELIFLRNRNPERGSIQNNKQVLRNLINSSCDQPLGYPMYVSPLTTSYLGTHRQLKN
VWGGPVSLDRIRTWLRTKWLRMRKDCHAG-QHSGGNIEDVDGGGPP----AAGRANAPSG
ESWESSTEQPRRARNR--------DRTRRTG----RRKGRSQSVQAPAALSQRPPASSLS
GPVLESHQAFMQTSSSVHELAQRLSGSQLSLHNSAASLPSQPPAVPTTGH-LSVRERAEA
LIRSSLGSSTSSTLSFLFGKRSFSSALVISGLSAAEGGNTSDTQSSSSVNIVMGPSARAA
SQATRHFSE-PCEPTDAT-EQGRLQDRRQAEAVAE-SLGVMCRR-ASQEDMGLDDTASQQ
SASDEQ

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------MASCQYSL
LK-----------SVQPDPASPIHGHNQIIMYSRPVYFCILCGLILLLDAGSKDKNPTIY
TVYGLKLFSPGSLQSARDHVIVFLYCFPAISLLGLFPQINTFCIYLLEQIDMLLFGGSAA
AGLISAL--YSISRSFVVVIVLYAFCFNAVK-EPWDARHIPALFSAFCG-LLVALSYHLS
RQSSDPSVL-MSLIQCKFFPHFLRQNL---EDSSTDPLPEKMR--------ESVKEILKS
DLIVCTVAAVLSFAVSASTVFLSLRPFLSIVLFALAWTVGFVT-HYILPQLRKHHPWLWI
SHPILKNKEYQQREVRDAAHLMWFERLYVWLQCFEKYILHPAIILNALTIDAFSVSKYRR
FGTHCDIFLITI--AGMKLLRSSFCNPV--HQFVTLSFTVIFFQFDYRDISENFLLDFFM
MSIVFHK--LWDLLQKLQFVLTYIAPWQIAWGSSFHVFAQLFSIPH--------SAMLFF
QTLATSIFSTPLSPFLGSVIFITSYARPVKFWEKNYNTK---RVDHSNTRLAIQIEKDPG
ND-DNNLNSIFYEHLTRSLQESLCGDLILGRWGNYSSGDCFILASDYLNAFVHLIEIGNG
LVTFQLRGLEFR-GTYCQQREVEAITEGDEDNEGCCCCQPGHLPHLLSCNAAFNLRWLTW
EITRTQYILEGYSIIDNNAATMLQVFDLRRILIRYYIKSIIYFTANSPKISHWIKDESIQ
KALQPYAKWHYIERDLAMFNINIDEDYVPCLQGITRASFCSVYLDWIQYCAGKRR-----
--EH

PF05041 // ENSGT00390000013164_1_Domain_0 (1865, 2098)

LDCDEDSPLVTLSFALCILGRRSLGTAAHNMAISLDSFLYGLHALFKGDFRITAKD
EWVFADMDLLHKVVAPAVR-----MSLKLHQDQFTCPDEYEDHAILYEAIQSFEE-KIVI
CHEGDPAWRRAVLSNREELLTLRHIVDEGTDEYKVIMLHKSYLSFKVIKVNKECVRGFWA
GQQQELIFLRNRNPERGSIQNNKQVLRNLINSSCDQPLGYPMYVSPLTTSYIGTHSQLMS
IWGGPVSLDNIKTWFRSKWLRMRKDCHAS-HNSGSSTEEVESGGGSSSSR------NSAS
NSSQSSSSQHTRNGTPQLLPS-SQDCHQYAG----RRKYRSQSVQTHAALNQRPPVSSRS
EPVVESYQPFIQASTSAHEIAQRLSRSQLSFHNSVTSVYR-----------------AEA
VLRSSLASSTSSTLSLLFGKRSFSSALVISGLSAADGGNTTDTQSSSSVNITMGPSARAA
SQAKLKQ----CLGPVWL-LP-P----ALLSAFYL-AREVF------QVLW---------
------

------------------------------------------------------------
-------------------------MVSQGLQLLR-------QGVWAALTGGWYHDPEQS
KFNNSC--H-------LYLWLILL-------LLP--------MALHLAFPPSTI----TA
FVYCSSVTFLFTVIKVVNYRLHLMFDRGDVIQQKVSWHEGKQNKEAKR----DN-AIRHI
NL--GNNVGDSGAVEEIKRNGSTPTIHSSIKVQAILSHHSSG-VLELPAQETIEDLKGVL
VLEDQSVPP-VSSTSPCVKADILSASMALMSNS-TTSAIVAKPNAMETFINSATSEKEE-
KVQ-PCGVV--ED-ISLDKGMVKKLPNLSLSQYDILKTGISFEPWSCDNSVII-SEHLSN
PKCFMREKLLSTSAQDSVTTS-CLPCSTVAAKRS-DGPVR--------------------
----SSSYVDG-MKGHLDNSESEVALALVDNSLPGDSVTLHEPIKIVITMSSTQNS-ATD
LEGSHHLKATGTEKSSSDPESGFVTA---N-QHSSEQMKIPVITFELSDDN---GGHAYQ
EISESLRTPDNLN-VDASSNQCSG--YESGEQDNVAKEYSDSLAHSPKEVNTSPE----N
ASENINITSSHSKERQLNLDVPSYKGTHEKRHARVLSVDSGTDVFLSKNSSETVSD-KEK
LLPTSKSDLEAKEGQIPNESNFLEFVSLLESINTSKATTSDS---KGENTKDKGAAG---
-------DVCSTEKNEESLETEKHCAEKENHGSSKQDRTEMQSQDSAAINPTVSESMKFT
AHYQSTRQRQIIYRVTSQQDSSVLQVISGPDASLQEEMSVDAMHVFIDEN-GDIRSCYLK
AGTQKEGNIG---PNYDCISNAHETHFSSSSTTTSESQAESSGDHGPSALQQQLLLMVAR
RTLSETQR-----------HFSEDLEDSSCSSTQRKINR-QFYKFIIFPGKWIKIWYDRL
ALLALLD---RTEDIKENVLAILLIILVSFLGFVIMNQGFCKDIWVLLFCLIMASCQYSL
LK-----------SVQPDPASPIHGHNQVITYSRPVYFCVLCGLILLLDAGSKNRSPPIF
TVYGLKVFSPGSFRAARDHVIGFLYCFPAISLLGLFPQINTFCIYLLEQIDMLLFGGSAA
AGMISSL--YSISRSFIVVTVLYLFCFNAVK-EPWDAQHIPALFSAFCG-LLVGLSYHLS
RQSSDPTVL-MSLIQCKYFPHLLHQHL---EDAQEDPLPEKMK--------ESVRETLKS
DLIVCSVAAVLSFAVSASTVFLSLGRFLSLVLFASAWTVGFVT-HYILPQLRKHHPWMWI
SHPVLKNKEYCQREVRDAAHLMWFERLYVWLQCFEKYILYPAIILNALTNDAFSISKSNR
LTPHCDIFLITV--AGMKLLRSSFCNPI--HQFVTLSFTVIFFKFDCNGFSENFLFNFFM
MSIVFNK--LWDLLQKLQFIMTYIAPWQIAWGSSFHVFAQLFAIPH--------SAMLFF
QTLATAIFSTPLSPFLGSVIFLTSYARPVKFWERNYNTK---RVDHSNTRLVLQIEKDAG
ND-D-NLNSIFYEHLTRSLQESLCGDLILGRWGNYSSGDCFILTSDYLNAFVHLIEIGNG
LVTFQLRGLEFR-GTYCQQREVEAITEGDEDNEGCCCCKPGHVPHLLSCNAAFNLRWLTW
EIMRTQYILEGYSIIDNNAATMLQVFDLRRILIRYYIKSIIYFTASSPKILYWLRDESFQ
KTLQPFSKWHYIERDFAMFNINIDDDYVPCLQGITRASFCSVYLDWIQFCAGKRV-----
--E

PF05041 // ENSGT00390000013164_1_Domain_0 (1864, 2098)

CIECDEDSPLVTLSFALCILGRRALGTASHNMAISLDSFLHGLHALFKGDFRITSRD
EWVFADMDLLHKVVAPAIR-----MSLKLHQDQFTCPDEYEDPAILYEAIQSFEE-KVVI
CHEGDPAWRSAVLSNKEELLTLRHVVEEGTDEYKIIMLHKGYLSFKVIKVNKECVRGLWA
GQQQELIFLRNRNPERGSIQNNKQVLRNLINSSCDQPLGYPMYVSPLTTSYIGTHRQLKN
IWGGPISLDNIKMWFRNKWLRMRKDCHPN-HNSGGNPDDGASRNGSASSC------NPAN
NSSQSSSSQHTRDSTPQLQPP-LQ-VAPFPG----RRKFRSQSVQTHTALNQRPPRSSHS
GPILESHHPFIPSSTSAHEIAQGLSGSQLSFHNSANSVFSHTPAIPALGQ-LTIQERAGA
VLRSSLASSTSSTLSLLFGKRSFSSALVISGLSAADGGNTSDTQSSSSVNIAVGPSARAA
RCTVQETTQQMSEDYEAT-ESKQRKDLGMTHTLLM-SQMLECRR-ASQEDMALEDTASQH
SLSEEQ

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------LNALTLDAFSISNYRR
LGTHWDIFLMIT--AGMKLLRTSFCNPV--HQFVTLSFTVVFFHFDYKEISESFLLDFFM
VSIFFSKAMLGDLLHKLQFVMTYVAPWQMAWGSSFHVFAQLFAIPH--------SAMLFF
QMIATSIFSTPLSPFLGSVIFITSYVRPVKFWEKNYNTK---RVDNSNTRLAVQIEKDPG
SD-DNNLNSIFYEHLXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXX-XTYCQQREVEAIMEGDEDDGGCCCCQPGHLPHLLSCNAAFNLRWLTW
ETTRTQYILEGYNIIDNNAATLLQVFDLRRILIRYYIKXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-
X---XXXXXXXXXX

PF05041 // ENSGT00390000013164_1_Domain_0 (1875, 2098)

XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXX-----XXXXXXXDQFTCPDEYEDPMILFEAIQSFER-KVVI
CHEGDPAWRSAVLSNREELLTLRHVVDEGADEYKVLMLHKSFLSFRVIKVNKECVRGLWA
GQQQELIFLRNRNPERGSIQNNKQVLRNLINSSCDQPLGYPMYVSPLTTSYLGTHRQMED
VWGGPVSLSRIWTWFRTKWLRMRKDCHAGXXXXXXXXXXXXXXXXXX---XXXXXXXXXX
------XXXXXXXXXXXXXXXX--XXXXXXXXXXXRRKGRSRSVQAHSALSQRLPISSLS
RPVLESHQTFIQTSTSVHELAPRLSGSQLSLHNSAASLHSQPPPATTTGH-LSVRERAEA
LIRSSLGSSTSSTLSFLFGKRSFSSALVISGLSAAEGGNTSDTQSSSSVNIVMGPSARAT
GHATRHFSE-PCEPTEAA-EQGRLSNRRLEVM--AETPGVMCRA--SQEDM-LDDTASQQ
SASDEQ

------------------------------------------------------------
-------------------------MGSQVLQLLR-------QGVWAALTGGWYHDPDQS
KFTNSC--H-------LYLWLLLL-------LLP--------LALHLAFPPDAI----TV
FFYCSSVTIFFTIIKLISYRLHLMFDKGEVIQRRPPGKKEKQSKDKEAN--GDHITNHRN
P--SNNGQINSGKKEA-DRTLSTPPLHGSSGRQSINSHHSSG-LLDLPAQETVEDLKGVI
LSDDQPIAP-VPSTSPGIKTESLPASKAPVLGTMTTSAIPLKPVVAETGIGDQGKERGG-
RGQ-PPFHHRSEGG-LVDRETVKKLPCLSLSQYDLLETDVSVQPWGSENSVLI-PEPGHY
--ASIRDKLQSKSPQDSLSSS-CPQCNTVIARPG-QEQ----------------------
----VSQQVDSTLNQDTGNSDSEVAVTLIDTSQPGDPLSLHEPIRIVITMSSTPNS-MTD
LESSLHLKAVGTQPSGFQADAEPAPPGAAGPPHV-EQMRIPVITFQLSEDAG---GMVCP
ESNGSGRSPERLT-VEASSNPCSG--YESGEGGSATQDHSPSP-GDHSATPPP-TPNMIC
A-------SEVGMEAQANLDPSSCRTSQEKRHARVLSVDSGTDVFLSKSYTEIIND-KEQ
TMPTSKSDLEAKEGQVPNESNFLEFVSLLESINTSKVVVSNQRNEPTEQDKDSRLPA---
-------DNCSQEKKEEILESEKPSGPI-----ATQGKPDVQSQDHTSTSPGLTEPAKIP
TLFQGNRQRQIIYRVTSQQDSSVLQVVSGPETSVQDEMSVDAMHVFIDEH-GEIKSCYLK
SGNQKEGPFQHQPSNYEGFSHAGDLQISSSSTTTSESQDPSSGDPAVSALQQQLLLMVAR
RTQSETPRRISP--TKRNTHLSRDLEDSSSSSTQGKFNREQFYKFIIFPGKWIKVWYDRL
TLLALLD---RTEDVKENVLAVLLIILVSLLGFLTLNQGFCKDIWALLFCLIMASCQYSL
LK-----------SVQPDPASPIHGHNQIITYSRPIYFCVLCGLILLLDTGAKARHPPTY
TVYGLKLFSPGSLQWARDLLIVFLYCFPAISLLGLFPQINTFCIYLLEQIDMLFFGGSAV
SGLLSAV--YSVARSASAAAVLHVFCFSAVK-EPWSTQHIPALFSAFCG-LLVALSYHLS
RQSSDPSVL-LSFIQCKLLHKFLHQNL---EELASDPLPMKMK--------ESVKDILKS
DLIICSVAAVLSFAVSASTVFLSLRPFLSIVLFALAGAVGFVT-HYLLPQLRKHHPWMWI
SHPILKNREYQQREVRDVAHLMWFERLYVWLQCFEKYILYPAIILNALTTDAFSISNYRR
LGTHWDIFLMVI--AGMKLLRTSFCNPV--HQFTHLGFTVIFFHFDYKDISESFLLDFFM
VSILFSK--LGDLLHKLQFVMTYVAPWQMAWGSSFHVFAQLFAIPH--------SAMLFF
QTFATSIVSTPLSPFLGSVIFITSYVRPVKFWEKNYNTR---RVDNSNTRLVVQIEKDPG
SD-GNNLNSIFYEHLTRALQESLCGDLILGRWGNYSSGDCFILASDYLNAFVHLIEIGNG
LVTFQLRGLEFR-GTYCQQREVEAITEGDEDDRGCCCCKPGHLPHLLSCNAAFNLRWLTW
EIARTQYILEGYSIMDNNAATMLQVFDLRRILIRYYIKSIIYYMVTSPKLFSWIKNESLL
KTLQPFAKWHYIERDLAMFHMNIDDDYVPCLQGITRASYCNVYLEWIQYCAQKRQEPSK-
P---LE

PF05041 // ENSGT00390000013164_1_Domain_0 (1867, 2097)

SDEDSPLVTLSFALCILGRRALGTAAHNMALSLDSFLYGLHALFKGDFRITARD
EWVFTDIDLLHKVVVPALR-----MSLKLHQDQFTCPDEYEDPAVLYEAIQSFEK-KVVI
CHEGDPAWRGAVLANKEELLTLRHVVDEGTDEYKVLMLHRSFLSFKVIKVNRECVRGLWA
GQQQELIFLRNRNPERGSIQNNKQVLRNLINSSCDQPLGYPMYVSPLTTSYLGTHRQLKN
VWSGPLTLDSIRAWLRTKWLRVRKDCDAAGQPGAGNTEDV-DAARAP---PAGGNSAPSG
ESRESSAEQPRKDGSRHWSP-R--EGTRRPG----RSKGRSQSVQAHRALSQTPPALRAS
GP------AFLQTSTSVHELAPRRSGSRLSLCPSAASLHSQPPAAPAAGP-LSVRERAEA
LLRSSLGSSTSSTLSFLFGKRSFSSALVISGLSAAEGGNTSDTQSSSSVNIALGPSARAA
SQSTRHFSE-PCEHTEVT-EQGLLRDHHVA-----ENLGVMCRR-ASQEDMGLDDTASQQ
SASDEQ

------------------------------------------------------------
-------------------------MASQVLQLLR-------QGVWAALTGGWYHDPEHS
KFTNSC--H-------LYLWLFLL-------LLP--------LALHLAFPPNVL----TA
LFYCGSVTIFFAVIKLISYRLHLMFDKGEAIQHRSPRKRSKRKPEGEAS--SQHTARHKN
PS--NNRQIHSTKKEEPRGSLTTPPLCCSSRGQSVHSQHSSG-PLELPAQETVEDLKGVV
LSEDQPEAL-ASSTSPGMKSESLPASQGRTPEPTPRPACPLKPVTTELFTARKGKESGG-
TAQ-RPARHRSESG-LVNPGALKKLPQLSLSQYDLLETDISFQPWGSEHSVLL-PQ-PNC
TQGATRAQPQNRSPQDSLSSS-CCQCNTVLAKPT-E-EELT-------------------
---RTSGQVELPLNQEVVDSDGEVAVTLIDTSQPGEPLSLHEPIKIVITMSSTQNS-ISD
LESSLHLRVTSSDRTSVRSSAESAGSGGAGPADP-EQVRIPLITLELTEDGG-GRGVSCS
EGNGGERTPERME-VM-SPDRCS----GSGPGD-----GSPT----PGSTLATLTPRVDP
E-------SEGSKEGQANLDPASCKSSHEKRHARVLSVDSGTDVFLSRSTKEVVSD-GEK
PIPTSKSDLEAKEGQIPNESNFLEFVSLLESISTSKVVAPDS---PAEQKGASQGPE---
-------GHASPGTKEEAVENEKPNGRD-----PKPGKPDLPSQDPANGSPVFTQPAKSA
ALFQGSRQRHIIYRVTSQQDSSVLQVISGPETSVQEEMSLDAMHVFIDEH-GEVRSCYLK
SGNQKEGSSQHPPLNPDCVSHARGILLSSSSSTATGSPDPSSGDPAVSALQQQLLLMVAR
RTQSETPRH-----------VSQDLEDSSRSSAQGKFNREQFYKFIVFPGKWIKVWYDRL
TLLALLD---RTEDVKENMVAVLLSVLVSLLGFLTLNRGFCRDLWVLLFCLVMASCQYSL
LK-----------SVQPDPASPIHGHNQIIAYSRPIYFCMLCSLILLLDAGAKAKHPPSY
VVYGLKLFTPETLQAVRDHLIVFLCCFPAISLLGLFPQINTFCTYLLEQIDMLLFGGSAV
SGITSAV--YSVGRSVLAAALLHAFCFSAVK-EPWSTQHIPALFSAFCG-LLVALSYHLS
RQSSDPSVL-LSFIQCKLLPKCLHQNL---EESATDPLPQRMK--------DSVKDVLRS
DLVICSAAAVLSFAVSASTVFLSLRPFLSIVLFALAGTVGLIT-HHLLPQLRKHHPWMWI
SHPVLRSKEYQQREARDIAHLMWFERLYVWLQCFEKYLLYPAIVLNALTLDAFSISNYRR
LGTHWDIFLMIT--AGMKLLRTSFCNPV--HQFANLGFTVIFFHFDYKDISESFLLDFFM
VSIVFTK--LGDLLQKLQFVLAYVAPWQMAWGSSFHVFAQLFAIPH--------SAMLFF
QTFATSIFSTPLSPFLGSVIFITSYVRPVKFWERSYNTR---RMDNSNTRLAVQMERDPG
SD-DNNLNSIFYEHLTRTLQESLCGDLVLGRWGNYSSGDCFILASDDLNAFVHLIEIGNG
LVTFQLRGLEFR-GTYCQQREVEAIMEGDEDDRGCCCCKPGHLPHLLSCNAAFHLRWLTW
EITRTQYILEGYSIIDNNAATMLQVYDLRRVLIRYYVKSIIYYMVTSPKLVSWVKNESLL
KSLQPFAKWHHIERDLAMFNINIDDDYVPCLQGITRASYCNVFLEWIQYCAGKRQELSK-
TLEHV

PF05041 // ENSGT00390000013164_1_Domain_0 (1866, 2097)

DSDEDSALVTLAFALCILGRRALGTAAHNMAMSLDSFLYGLHALFKGDFRVTARD
EWVFADMDLLHKVVVPAIR-----MSLKLHQDQFTCPDEYEDPAVLYEAIRSFAK-KVVI
CHEGDPAWRGAMLSNKEELLTLRHVVDEGADEYKVIMLHRGFLSFKVIKVNKECVRGLWA
GQQQELIFLRNRNPERGSIQNNKQVLRNLINSSCDQPLGYPMYVSPLTTSYLGTHKQLQS
VWGGPVTLNRVRTWFQTRWLRMRKDCSVGQRSGGGNIEDG-EGGAVP---SAGGGSAPNG
ESRDGSTEQPRKGGTQQWSSPR--GEAQRAG----RRKGRSQSVQAHSAISQRPPTLSSS
GPILESHQAFLQTSTSVHELAQRPSGSRLSLHTSAASLHSQPPPVTTTGH-LSVRERAEA
LIRSSLGSSTSSTLSFLFGKRSFSSALVISGLSAAEGGNTSDTQSSSSVNIVMGPSARAA
GHAARHFSE-PCEPTDSP-EQGQLQDGRLAEAMEE-NLGVLCRR-ASQEDMGLDDTASQQ
STSDEQ

------------------------------------------------------------
-------------------------MVSQALQLLR-------QGVWAALTGGWYHDPEQS
TFTNSC--H-------LYLWLFLL-------LLP--------LALHLAFPPNAI----TA
FFYCSSVTVFFTIIKLVSYRLHLMFDKGEVIQQKPSRKKEKPNKDKEAN--KEHITNHKI
PS--NNRQINSGKKEEALPSLSTPPLRCSSRGQNINSHHSSG-PLELPAQETVEDLQGVV
LSEDHAVAP-VSSTSSGIKMESSAVSKGRGPDPVTMPAGPRRPAVAETRVSDRVKERGG-
RAQ-PPFRHRSEGG-LVEKEALKKLPHLSLSQYDLLETDVSFQPWGSENSVLS-PEPVIY
AQGSLQEQLQSQSPADSLSSS-CPQCDTVIARAA-CLPLD--------------------
----ATRHGDPPRTQEADCSDSEVAVTLIDTSQPGDPLSLHEPIKIVITMSSTPNS-MTD
LESSLHLKVIGTEGAGLKSDAEPATPGVASPPNT-EQMRIPVITLELSEDRG--GGAKCP
ENNGSDRTPERLM-VEVSSNQCSG--YESGEGGNATKDGSPSL-GDRCETNPLFAPHEVP
V-------SEGAEEGQANLDPSSCKTSHEKRHTRVLSVDSGTDVFLSKSSTEVVND-KEK
TMPTSKSDLEAKEGQIPNESNFLEFVSLLESINTSKLTASGQRNDPGEQNQDSGLVG---
-------DNGSPEKKEEIQESEKPNGHS-----SKQGKPDMQSQDHTSTSPVLTEPAKIT
TLFQGSRQRQIIYRVTSQQDSSVLQVISGPETSVQDEMSMDAMHVFIDEH-GEIRSCYLK
SGNQREGPFQHLPSNHDSFSHAREMQISSSSTTTSESQDPSSGDPAVSALQQQLLLMVAR
RTQSETPR-----------HLSQDLEDASHSSTQGKFNREQFYKFIIFPGKWIKVWYDRL
TLLALLD---RTEDIKENVLAVLLIVLVSLLGFLTLNQGFCKDAWVLLFCLVMASCQYSL
LK-----------SVQPDPASPIHGHNQIITYSRPIYFCVLCGLILLLNTGAKARHPPTY
VVYGLKLFSPRSLQSARDLLIVFLYCFPAISLLGLFPQINTFCIYLLEQIDMLFFGGSGL
HGMESRQ--LGVALTFLMCANTHKDAYA-CT-DAHSRTHAPCIYTTFFPFLLMAESYGQS
NQGPDPGISERSFIPCRLLPKFLHPSL---EELAADPLPKKMQ--------ESVKDILKS
DLVICSVAAVLSFAISASTVFLSLRPFLSVVLFALAGSVGFVT-HYMLPQLRKHHPWMWI
AHPILKNREYQQREVRDVAHLMWFERLYVWLQCFEKYILYPAIILNALTIDAFSISNYRR
LGTQCPHVLRSI--NGSQLSYLSYIKKPLYQKISSVHFPLYYFSFPSTSLSVCFSIFFFE
LAHLFSH--LGDLLHKLQFVLTYVAPWQMAWGSSFHVFAQLFAIPRIL------CASVFI
CELGVTVYRSMLSTEPCSSLFCSSVCEPRSFWASSSTNEHQVSMLNSPSYLCVCLCCEPG
SD-DNNLNSIFYEHLTRALQESLCGDLVLGRWGNYSSGDCFILASDYLNAFVHLIEIGNG
LVTFQLRGLEFR-GTYCQQREVEAIMEGDEEDRGCCCCQPGHLPHLLSCNAAFHLRWLTW
EITRTQYILEGYSIVDNSAATMLQVFDLRRILIRYYIKSIIYYMVTSPKLLSWIKNESLL
KSLQPFAKWHYIERDLAMFNINVDDDYVPCLQGITRASFCNVYLEWIQYCARKRQEPSK-
N---L

PF05041 // ENSGT00390000013164_1_Domain_0 (1866, 2098)

DSDEDSALVTLSFALCILGRRALGTAAHNMALSLDSFLYGLHALFKGDFRITARD
EWVFADMDLLHKVVAAPPAVTTVSSLTSFPQDQFTCPDEYEDPGALYEAIQSFEK-KVVI
CHEGDPAWRGAVLSNKEELLTLRHVVDEGTDEYKVIMLHRGFLSFKVIKVNKECVRGLWA
GQQQELIFLRNRNPERGSIQNNKQVLRNLINSSCDQPLGYPMYVSPLTTSYLGTHRQLQS
VWSGPVPLDSIRTWFLTKWLRVRKGCDSG-QPGTGNIEDADGRAAP----SAGRSRAPGG
ESQESSTEQPRKDGMRHWSPR---EGTQKTG----RRKGRSQSVQAHAALSQRPATLSSS
GPIVESHQAFLQTSTSVHELAQRLSGSRLSLHTSAASLHSQPPPVTTTGH-LSVRERAEA
LIRSSLGSSTSSTLSFLFGKRSFSSALVISGLSAAEGGNTSDTQSSSSVNIVMGPSARAN
SQATRHFSE-PCEATEAT-EQGQCHDCHPAGTMAE-NGELLCRR-ASQEDMGLDDTASQQ
SASDEQ

------------------------------------------------------------
-------------------------MVSQVLQLLR-------QGVWAALTGGWYHDPEQS
KFTNSC--H-------LYLWLFLL-------LLP--------LALHLAFPPNVI----IV
FFYCSAVTIFFTIIKLVSYRLHLMFDKGEVIQQKPSRKEEKPNKDKEAK--GEHITNPKN
PS--NNRQIHNGKKEEASRNLSTPPLRCSSRGQSITSHHSSG-PLELSAQETVEDLKGVI
LSEDHPIAP-VSSTSPGIKMESLPACQAHMLETMPKSAIPVKPIATETLINGKGKERGG-
KGQ-PPLRHRSEGG-LVDKGPLKKLPHLSLSQYDLLETDISFQPWGSENSVLI-PEPVSC
PQGSVRERVQSKSPQDSLSSS-CPQCDTIVAKPV-EEPADTSCQVD--------------
----TSCQVDLPLNQEVDSSDSEVAITLIDTSQPGDPLSLHEPIKIVITMSSTPNS-MTD
LESSLHLKVVGIEKTGVKSDAEPTNPGAASSPNA-EQISIPVITLDLPEGGG--GGVPCS
EGNGSERTPERLK-ARVSTNQCSG--YGSGEGGSATKDHSSSS-REPWESASRLTPDTAS
E-------SKVGKEGLTNLDPLSCKSSHEKRHARVLSVDSGTDVFLSKSSAEIVND-TEK
TMPTSKSDLEAKEGQIPNESNFLEFVSLLESINTSKMAASNQLNGSAEQNEESGLLQ---
-------DNTSQEKKEEILENEKPSGHS-----PKKGKPDLQSQDHTSTSPVCTQPAKTT
AFFQGNRQRQIIYRVTSQQDSSVLQVISGPETSVQEEISVDAMHVFIDEH-GEIRSCYLK
SGNQKEGPLQPLPSNCDCLSQAREMQVSSSSTTTSESQDPSSGDPAVSALQQQLLLMVAR
RTQSETPRH-----------VSQDLEASSCSSTQGKFNREQFYKFIIFPGKWIKVWYDRL
TLLALLD---RTEDIKENVLAILLIVLVSLLGFLTLSRGFCKDMWVLLFCLVMASCQYSL
LK-----------SVQPDPASPIHGHNQIITYSRPIYFCVLCGLILLLDTGAKARHPPSY
IVYGLKLFSPVFLQSARDYLIVFLYCFPAISLLGLFPQINTFCIYLLEQIDMLFFGGSAV
SGITSAV--YSVARSFLAAALLHAVCFSAVK-EPWSTQHIPALFSAFCG-LLVALSYHLS
RQSSDPSVL-MSFIQCRLLPKFLHQNL---EESAADPLPKKMK--------DSVTDVLKW
DLIVCAVVAVLSFAVSASTVFLSLRPFLSIVLFALAGAVGFVT-HYLLPQLRKHHPWMWI
SHPILKNKEYHQREVRDVAHLMWFERLYVWLQCFEKYILYPALILNALTIDAFLISNHRR
LGTHWDIFLMIIA--GMKLLRTSFCNPV--DQFINLSFTVIFFHFDYKDISESFLLDFFM
VSILFSK--LGDLLHKLQFVLTYVAPWQMAWGSSFHVFAQLFAIPH--------SAVLFF
QTIATSIFSTPLSPFLGSVIFITSYVRPVKFWEKNYNTR---RVDNSNTRLAVQIERDPG
ND-DNNLNSIFYEHLTRTLQESLCGDLVLGRWGNYSSGDCFILASDDLNAFVHLIEIGNG
LVTFQLRGLEFR-GTYCQQREVEAIMEGDEDDRGCCCCKPGHLPHLLSCNAAFHLRWLTW
EITRTQYILEGYSILDNNAATMLQVFDLRRILIRYYIKSIIYYMVTSPKLLSWIKNESLL
KSLQPFAKWHYIERDLAMFNINIDDDYVPCLQGITRASFCNVYLEWIQHCARKTQEPSK-
T---L

PF05041 // ENSGT00390000013164_1_Domain_0 (1866, 2097)

DSDEDSPLVTLSFALCTLGRRALGTAAHNMAISLDSFLYGLHALFKGDFRITARD
EWVFADMDLLHKVVAPAIR-----MSLKLHQDQFTCPDEYEDPAVLYEAIQSFEK-KVVI
CHEGDPAWRGAVLSNKEELLTLRHVVDEGADEYKVIMLHRSFLSFKVIKVNKECVRGLWA
GQQQELIFLRNRNPERGSIQNNKQVLRNLINSSCDQPLGYPMYVSPLTTSYLGTHKQLKN
VWGGPITLDRIRTWFWTKWVRMRKDCNARQ-QSGGNIEDV-DGGGAP---ATGGNNAPSG
GSQESSTEQPRKGGAQHGVSSC--EGTQRTG----RRKGRSQSVQAHSALSQRPPMLSSS
GPILESRQTFLQTSTSVHELAQRLSESRLSLHTSATSLHSQPPPVTTTGH-LSVRERAEA
LIRSSLGSSTSSTLSFLFGKRSFSSALVISGLSAAEGGNTSDTQSSSSVNIVMGPSARAA
SQATRHLSE-PCEPTDAT-EQGQLRDQRPAEAVPE-TLGVVCRR-ASQEDMGLDDTASQQ
SVSDEQ

------------------------------------------------------------
-------------------------MVSQVLQLLR-------QGVWAALTGGWYHDPEQS
KFTNSC--H-------LYLWLFLL-------LLP--------LALHLAFPPNAF----IV
FFYCSAVTIFFTIIKLVSYRLHLMFDKGEVIQQKPSRKEEKPNKDKEAK--GEHITNHKN
PS--NNRQIHNGKKEEASRNLSTPPLRCSSRGQSITSHHSSG-PLELSAQETVEDLKGVI
LLEDHPIAP-VSSTSPGIKMESLPASQAHMLGTTPKSVIPVKPVATETLINGKGKERGG-
KGQ-PPLRHRSEGG-LVDKGPLKKLPYLSLSQYDLLETDISFQLWGSENSVLI-PEPVSC
PQGSIRERVQSKSPQNSLSSS-CPQCDTIVAKPV-EEPADTSCQVD--------------
----TSCQVDLPVNQEVDSSDSEVAVTLIDTSQPGDPLSLHEPIKIVITMSSTPNS-MTD
LESSLQLKVVGTEKTSVKSDAEPTNPGAAGSPNA-EQISIPVITLDLPEGGG--GGVPCP
EGNGSERTPERLK-ARVSTNQCSG--YGSGEGGNAIKDHSSSS-REPWESVSRLTPDTAS
E-------SKVGKEGQANVDPSSCKSSHEKRHARVLSVDSGTDVLLSKSSAEIVND-TEK
TMPTSKSDLEAKEGQMPNESNFLEFVSLLESINTSKMAASNQLNGSAEQNEESGLLR---
-------DNCSQEKKEEILENEKPSGHS-----SKQGKPDLQSQDHTSTSPACTQPAKTT
AFFQGNRQRQIIYRVTSQQDSSVLQVISGPETSVQEEISVDAMHVFIDEH-GEIRSCYLK
SGNQKEGPLQPLPSNYDCLSQAREMQVSSSSTTTSESQDPSSGDPAVSALQQQLLLMVAR
RTQSETPRH-----------VSQDLEASSCSSTQGKFNREQFYKFIIFPGKWIKVWYDRL
TLLALLD---RTENIKENVLAILLIVLVSLLGFLTLSQGFCKDMWVLLFCLVMASCQYSL
LK-----------SVQPDPASPIHGHNQIITYSRPIYFCVLCGLILLLDTGAKARHPPSY
VVYGLKLFSPLFLQSARDYLIVFLYCFPAISLLGLFPQINTFCTYLLEQIDMLFFGGSAV
SGITSAV--YSVARSVLAAALLHAVCFSAVK-EPWSMQHIPALFSAFCG-LLVALSYHLS
RQSSDPSVL-MSFIQCRLFPKFLHQNL---EESAADPLPKKMK--------DSVTDVLKW
DLIVCAVVAVLSFAVSASTVFLSLRPFLSIVLFALAGAVGFVT-HYLLPQLRKHHPWMWI
SHPILKNKEYHQREVRDVAHLMWFERLYVWLQCFEKYILYPALILNALTIDAFLISNHRR
LGTHWDIFLMIIA--GMKLLRTSFCNPV--YQFINLSFTVIFFHFDYKDISESFLLDFFM
VSILFSK--LGDLLHKLQFVLTYVAPWQMAWGSSFHVFAQLFAIPH--------SAMLFF
QTIATSIFSTPLSPFLGSVIFITSYVRPVKFWEKNYNTR---RVDNSNTRLAVQIERDPG
ND-DNNLNSIFYEHLTRTLQESLCGDLVLGRWGNYSSGDCFILASDDLNAFVHLIEIGNG
LVTFQLRGLEFR-GTYCQQREVEAIMEGDEEDRGCCCCKPGHLPHLLSCNAAFHLRWLTW
EITRTQYILEGYSILDNNAATMLQVFDLRRILIRYYIKSIIYYMVTSPKLLSWIKNESLL
KSLQPFAKWHYIERDLAMFNINVDDDYVPCLQGITRASFCNVYLEWIQHCAQKRQEPSK-
T---L

PF05041 // ENSGT00390000013164_1_Domain_0 (1866, 2097)

DSDEDSPLVTLSFALCTLGRRALGTAAHNMAISLDSFLYGLHALFKGDFRITARD
EWVFADMDLLHKVVAPAIR-----MSLKLHQDQFTCPDEYEDPAFLYEAIQSFEK-KVVI
CHEGDPAWRGAVLSNKEELLTLRHVVDEGADEYKVIMLHRSFLSFKVIKVNKECVRGLWA
GQQQELIFLRNRNPERGSIQNNKQVLRNLINSSCDQPLGYPMYVSPLTTSYLGTHRQLKN
VWGGPITLDRIRTWFWTKWVRMRKDCNARQ-HSGGNIEDV-DGGGAP---TTGGNNAPSG
GSQESSAEQPRKGGAQHGVSSC--EGTQRTG----RRKGRSQSMQAHSALSQRPPMLSSS
GPILESRQPFLQTSTSVHELAQRLSGSRLSLHTSVTSLHSQPPPVTTTGH-LSVRERAEA
LIRSSLGSSTSSTLSFLFGKRSFSSALVISGLSAAEGGNTSDTQSSSSVNIVMGPSARAA
SQATRHLSE-PCEPTDAT-EQGQLRDRRLAEAVAE-TLGVVCRR-ASQEDMGLDDTASQQ
SVSDEQ

------------------------------------------------------------
-------------------------MLTQQ-KVRK-------GTEWEATLT-------FL
LSFSFCLPQ-------GFLWFVMGTNTLKTFLRPLRPDAEGYTSSTTAFPPNAI----IV
FFYCSSVTIFFTIIKLVSYRLHLMFDKGEVIQQKSSKKKEKPNKDKETN--SERITSHKN
PS--NNRRIHRGKKEEASQNLATPPLRCSSGGQGMNSHHSSG-L-----------SVGVI
LSEDQPAAP-VSSTSPGIKTASLAASQARMLEATPESVMPAKPVAAETFIHGKAKDRGG-
KMQ-PPLRHRSEGG-LEDKGPLKKSPHLSLSQYDLLETDVSFQLWGSEHSVLI-PEPVSC
PQGSIRGQVQSKSPQDSLSSS-CPQCNTVVAKPA-EGQAD--------------------
----TSCQVDLPLNQEVDSLESEVAVTLIDTSQPGNPLSLHEPIKIVITMSSTPNS-MTD
LESSLHLEVVGTEGTALKSDTELATPGVASPPHA-EQIRIPMITLEPSEDRG--GSVSRP
EGNGNERTPERPR-VEASASQCSG--HASGEGTGTTKDCSSSS-RDPGETAPPLTPDLAS
E-------SARGKESQASLDPASCKTSHEKRHARVLSVDSGTDVFLSKSSAEIINENKEK
TMPTSKSDLEAKEGQIPNESSFLEFVSLLESINTSKVVASDQSNGSAEQNEESGLLQ---
-------DNCSQEKKEEIPEREKPSGHD-----SKQGKPGLQSQDHTSASPVCAQPAKTP
AFFQGNRQRQIIYRVTSQQDSSVLQVISGPETSVQEEISVDAMHVFIDEH-GEIRSCYLK
SGNQKEGLLEHPSSHCDCLSQAREIQVSSSSTTTSESQEPSSGDPAVSALQQQLLLMVAR
RTQSETPRH-----------VSQDLEDSSCSSTQGKFNREQFYKFIIFPGKWIKVWYDRL
TLLALLD---RTEDVKENVLASLLIVLVSLLGFLTLNRGFCKDMWVLLFCLVMASCQYSL
LK-----------SVQPDPASPIHGHNQIITYSRPTYFCVLCGLILLLDTEAKARHPPGY
VVYGLKLFSPVSLQSARDYLIVFLYCFPAISLLGLFPQINTFCIYLLEQTDMLFFGGSAV
SGITSAV--YSMARSILATALLYAVCFSAVK-EPWSTQHIPALFSAFCG-LLVALCYHLS
RQSSDPSAL-MSFIQCRLFPKFLHQNL---EESAADPLAKKMK--------DSVKDVLKS
DLIICAVFAVLSFAVSASTVFLSLRPFLSIVLFALAGTVGFVT-HYLLPQLRKHHPWMWI
SHPILKNKEYHQWEVSDVAHLMWFERLYVWLQCFEKYILYPAVILNALTIDAFSISNHRR
LGTHWDIFLMII--AGMKLLRTSFCNPV--HQFINLSFTVIFFQFDYRDISESFLLDFFT
VSILFSK--LGDLLHKLQFVLTYVAPWQMAWGSSFHVFAQLFAVPH--------I----L
STIATSIFSTPLSPFLGSVIFITSYVRPVKFWEKNYNTK---RVDNSNTRLAVQIERDPG
ND-DNNLNSIFYEHLTRTLQESLCGDLVLGRWGNYSSGDCFILASDDLNAFVHLIEIGNG
LVTFQLRGLEFR-GTYCQQREVEAIMEGDEDDRGCCCCKPGHLPHLLSCNAAFHLRWLTW
EITRTQYILEGYSILDNNAATMLQVFDLRRILIRYYIKSIIYFMATSPKLLSWMKNESLL
KSLQPFAKWHYIERDLAMFNTNIDDDYVPCLQGITRASFCNVYLEWIHQKILKTILDTH-
T---LL---------------------TRTVIR

PF05041 // ENSGT00390000013164_1_Domain_0 (1894, 2097)

TLFYSLDSFLYGLHALFKGDFRITARD
EWVFADMDLLHKVVAPAIR-----MSLKLHQDQFTCPDEYEDPAVLYEAIQSFEK-KVVI
CHEGDPAWRGAVLSNKEELLTLRHVVDEGTDEYKVIMLHRSFLSFKVIKVNKECVRGLWA
GQQQELIFLRNRNPERGSIQNNKQVLRNLINSSCDQPLGYPMYVSPLTTSYLGTHRQLKN
VWRGPVTLDSIRMWLRTKWLRMRKDCDARQ-RSSGHAEDG-DGGGAP---AAGGSGVPSG
GSQESSAEQPRKDGSQHWASSR--EGTQRTG----RRKGRSQSVQARSALSQRPPTLSSS
GPILESRQAFLQTSTSVHELAQRLSGSRLSLHTSATSLHSQPPPVTTTGH-LSVRERAEA
LIRSSLGSSTSSTLSFLFGKRSFSSALVISGLSAAEGGNTSDTQSSSSVNIAMGPSARAA
GHAARHFSE-PCEPTDAT-EQRQLRDQRRAEAMAE-NVGVICRR-ASQEDMGLDDTASQQ
SASDEQ

------------------------------------------------------------
-------------------------MVSQVLQLLR-------QGVWAALTGGWYHDPEQS
KFTNSC--H-------LYLWLFLL-------LLP--------LALHLAFPPNAI----IV
FFYCMSVTLFFTIIKLVSYRLHLMFDKGEVIQKRPSRKKEKSSKDKDAN--SEHMTNHKI
PS--NNRQIHNDRKEEATRTFPTPPLHCSSRGQSLNSHHSSG-PLELPAQETVEDLKGVI
LSEDQPIVP-VSSTSPGIKTQSLPASQVHMQETTPRSAKLVKPVATGTLINGKGKERGI-
KGQ-PPFRHRSEGG-LVDKGALKKLPHLSLSQYDLLETDVSFQPWGSENSVLI-PEPIDC
PQGSIREQFPKKSPQDSMSSS-CPQCDTIMAKPE-EELLE--------------------
----TSCQVDLPLNHEADYSDSEVAVTLIDNSQPGDPLSLHEPIKIVITMSSTPNS-MTD
LESSLHLKLIGTERTSGKSDTEPAIPRVASPTNT-EQIRIPVITLELSEDGE--EGVTCS
EGNRTEKTPERLQ-VEASSNQCSG--YGSGEG------GSPSP-RHHWETVPPVTSDVTP
K-------SEGGKEGQDNLDPLSCKASHEKRHARVLSVDSGTDVFLSKRCAEVIND-KEK
TIPTSKSDLEAKEGQIPNESNFLEFVSLLESINTSKVVACNQMNVSAQQSKESGPQ----
------EDNCSQEKKEEFLASEKPSGHN-----SKQGKPDLQSQDHPCTSPMFTQPPRTT
AFFQGNRQRQIIYRVTSQQDSSVLQVISGPETSVQEEMSVDAMHVFIDEH-GEIRSCYLK
SGNQKEGPSQYTPSNHERLSQAREMQISSSSTTTSESPDPSSGDPAVSALQQQLLLMVAR
RTQSDTPR-----------HVSQDLEDSSCSSTQGKFNREQFYKFIIFPGKWIKVWYDRL
TLLALLD---RTEDVKENVLAILLIVLVSLLGFLTLNQGYCKDMWVLLFCLVMASCQYSL
LK-----------SVQPDPASPIHGHNQIITYSRPIYFCVLCGLILLLDTGAKARHPPSY
VVYGLKLFSPASLQSARDYLIVFLYCFPAISLLGLFPQINTFCIYLLEQIDMLLFGGSAV
SGITSAV--YSVTRSVSSAILLHAFCFSAVK-EPWSTQHIPALFSAFCG-LLVALSYHLS
RQSSDPSVL-LSFIQCGLFPKFLHQNL---EESAADPLPKKMK--------DSVKDTLKS
DLIICSVAAVLSFAVSASTVFLSLRPFLSIVLFALAGIVGFVT-HYLLPQLRKHHPWMWI
SHPILKNKEYQQREVKDVAHLMWFERLYVWLQCFEKYVLYPAIILNALTIDAFSISNYRR
LGTHWDIFLMIM--AGMKLLRTSFCNP-V-HQFVNLSFTVIFFHCDYKDISESFLLDFFM
VSILFSK--LGDLLHKLQFIMTYVAPWQMAWGSSFHVFAQLFAIPHSA--------MLFF
QAIATSIFSTPLSPFLGSVIFITSYVRPVKFWEKNYNTR---RVDNSNTRLAVQIERDPG
ND-DNNLNSIFYEHLTRTLQESLCGDLVLGRWGNYSSGDCFILASEDLNAFVHLIEIGNG
LVTFQLRGLEFR-GTYCQQREVEAIMEGDEDDRGCCCCKPGRLPHLLSCNAAFHLRWLTW
EIMRTQYILEGYSIIDNNAATMLQVFDLRRILIRYYVKSIIFYMVTSPKILSWIKNESLL
KSLQPFAKWHYIERDLAMFNINIDDDYVPCLQGITRASFCNVYLEWIQYCAQKRQEPSK-
T---L

PF05041 // ENSGT00390000013164_1_Domain_0 (1866, 2098)

DCDEDSPLVTLSFALCILGRRALGTAAHNMAISLDSFLYGLHALFKGDFRITARD
EWVFADMDLLHRVVAPAIR-----MSLKLHQDQFTCPDEYEDPVVLYEAIQSFQK-KVVI
CHEGDPAWRGAVLSNKEELLTLRHVVDEGSDEYKVIMLHKSFLSFKVIKVNKECVRGLWA
GQQQELIFLRNRNPERGSIQNNKQVLRNLINSSCDQPLGYPMFVSPLTTSYLGTHRQLKN
VWGGPVTLDRIGTWFCTKWLRVRKDCNAG-QHSRGNIEDVDGGGAP----SAGGSNAPSG
DSQESSAEQPRKHGSQHWASPQ--EGMQRTG----RRKGRSQSVQAHSALSQRLPTLSSS
GPILESRQVFLQASTSVHELAQRLSGSRLSLHTSAASLHSQPPPVTTTGH-LSVRERAEA
LIRSSLGSSTSSTLSFLFGKRSFSSALVISGLSAAEGGNTSDTQSSSSVNIAMGPSARAA
SQATRHFSE-PYESPDTT-EQGQPGDQRLAEAVAE-SRGLTCRR-ASQEDMGLDDTASQQ
SASDEQ

------------------------------------------------------------
-------------------------MASQVLQLLR-------QGVWAALTGGWYHDPEHS
KFTNSC--H-------LYLWLFLL-------LLP--------LALHLAFPPNVL----TA
LFYCGLVTIFFAAIKIISYRLHLMFDKGEVVQHRSPRKRSKRRPEGEAS--SQHTASHKN
PS--NNRQLHSAKKEEPRGSLPTPPLRCSSRGQSVHSRH-SS-PLELPAQETVEDLKGVV
LSEDQPEAV-VSSTSPGIKSESLPASQGHTPELTPRPTEPVKRVTTETLTGRKGKEPGA-
TGQ-RPARHRSESG-LVNTGALKKLPHLSLSQYDLLETDISFQPWGSEHSALI-PQTTSC
PQGPTRAQSQSRSPQDSLSSS-CCQCNTVLAKPT-EEEELT-------------------
---RTSGQVELPLNQEVVDSDGEVAVTLIDTSQPGEPLSLHEPIKIVITMSSTPNS-MSD
LESSLQMKVTSSDGTNVRPDAEPSGPGVASPTDP-EQIRIPLITLELTEDGR-ERSISCP
ERNGGERTPERME-RM-PSDLCS----GCGSGDQDA------------------TSRVDP
E-------SEGSREGQANLDPTSCKSSHEKRHARVLSVDSGTDVFLSRSTKEAVSD-SEK
PIPTSKSDLEAKEGQIPNESNFLEFVSLLESINTSKVVAPNS---GAEQKEANQGPE---
-------DHASPGTKEETVESEKPSGHD-----PKPGKPDLPSQDHAIASPVFTQPAKTT
ALFQGSRQRQIIYRVTSQQDSSVLQVISGPETSVQEEMSLGAMHVFIDEH-GEIKSCYLK
SGNQKEGSSQHPPLNPDCVSRAREILLSSSSTTTSESPDPSSGDPAVSALQQQLLLMVAR
RTQSETPRH-----------MSQDLEDSSRSSAQGKFNREQFYKFIIFPGKWIKVWYDRL
TLLALLD---RTEDVKENVVAILLSVLVSLLGFLTLNRGFCRDLWVLLFCLVMASCQYSL
LK-----------SVQPDPASPIHGHNQIIAYSRPIYFCMLCGLILLLDAGAKARHPPSY
VVYGLKLFSPETLQSIRDHLIVFLCCFPVISLLGLFPQINTFCTYLLEQVDMLLFGGSAV
SGITSAV--YSVGRSVLVAALLHAFCFSAVK-EPWSTQHIPALFSAFCG-LLVALSYHLS
RQSSDPSVL-LSFIQCRLLPKFLHQNL---EESATDPLPQRMK--------DSVKDVLRS
DLVICSAAAVLSFAVSASTVFLSLRPFLSIVLFALAGTVGLIT-HHLLPQLRKHHPWMWV
SHPVLKSKECQQREARDIAHLMWFERLYVWLQCFEKYLLYPAIVLNALTLDAFSISNYRR
LGTHWDIFLMIT--AGMKLLRTSFCNPV--HQFANLGFTVIFFHFDYKDISESFLLDFFM
VSIVFTK--LGDLLHKLQFVLAYVAPWQMAWGSSFHVFAQLFAIPH--------SAMLFF
QTFATSIFSTPLSPFLGSVIFITSYVRPVKFWERSYNTR---RVDNSNTRLAVQMERDPG
SD-DNNLNSIFYEHLTRTLQESLCGDLVLGRWGNYSS-----------------------
-------------GTYCQQREVEAIMEGDEDDRGCCCCKPGHLPHLLSCNAAFHLRWLTW
EITRTQYILEGYRIIDNNAATMLQVFDLRRVLVRYYVKSIIYYMVTSPKLLSWVKNEPLL
KSLQPFAKWHHIERDLAMFNVNIDDDYVPCLQGITRASYCTVFLEWIQYCAGKRQELSK-
ALDHV

PF05041 // ENSGT00390000013164_1_Domain_0 (1866, 2097)

DSDEDSPLVTLSFALCILGRRALGTAAHNMAMSLDSFLYGLHALFKGDFWVTARD
EWVFADMDLLHKVVVPAIR-----MSLKLHQDQFTCPDEYEDPAILYEAIQSFEK-KVVI
CHEGDPAWRSAVLSNKEELLTLRHVVDEGADEYKVIMLHRGFLSFKVIKVNKECVRGLWA
GQQQELIFLRNRNPERGSIQNNKQVLRNLINSSCDQPLGYPMYVSPLTTSYLGTHKQLQS
VWGGPVTLNRMRTWFQTRWLRMRKDCSVGQRSG-GNIEDV-DGGAVP---AAVGSNAPSG
ESRDSSTEQPRKGGTQQWASPR--GGGHRAG----RRKGRSQSVQAHSAISQRPPTLSSS
GPILESHQAFLQTSSSVHELAQRPSSSRLSLHTSAASLHSQPPPVTTTGH-LSVRERAEA
LIRSSLGSSTSSTLSFLFGKRSFSSALVISGLSAAEGGNTSDTQSSSSVNIVMGPSARAA
GHATRHFSE-PCEPTDTP-EQGQLQDRRQAEAVAE-NLGVLCRR-ASQEDMGLDDTASQQ
SASDEQ

------------------------------------------------------------
-------------------------MASQVLQLLR-------QGVWAALTGGWYHDPEHS
KFTNSC--H-------LYLWLFLL-------LLP--------LALHLAFPPNTL----TA
LFYCGSVTIFFAVIKLISYRLHLMFDKGEAIQHQPPRKRDKTRPEREAS--HQRTASHKI
PS--NNKQIHNGKKEEPLGNLPTPPLRCSSRGQSVHSQHSLG-PLELPAQETVEDLKGVV
LSEDQPEAA-MSSTSPGIKSERLPASQVCTAEPTPRSTRLRKPVTTEILIGGKGKEPGT-
VQ--QLAHHRSEGG-LVNTGTLKNLPHLSLSQYDLLETDVSFQPWGSENSVLV-PQPTSL
HQGSTRAQSQSKSPQDSLSSS-CRQCSTVLAKPM-EEELT--------------------
---HTSCQVDLPLNQEVVDSDGEVAVTLIDTSQPGEPLSLHEPIKIVITMSSAPNS-ISD
LERSLHLKVTSSDKTSHRPDTEPSG-----SEDP-EQVRIPMITLQLSEDGG--G-ASCH
KGNRGEWTPERPK-MEMSPSHCSD--YGSGD------------------AGDPVLTQVDS
E-------SKGNRESKTNLDPASCRGSHEKRHARVLSVDSGTDVFLSKSSTEVVSD-REK
PIPTSKSDLEAKEGQVPNESNFLEFVSLLESINTAKVEAPDQVQSSAEQKGTSQGPE---
-------DHTSQGTREEAVESKRPGGHD-----PKPGKPDLPHGDRENTSPGSTQPAKTT
ALFQGSRQRQIIYRVTSQQDSSMLQVISGPETSVQ-EMSVDAMHVFIDEH-GEIRSCFLK
SGNQKEASLQHLPSNQDCVSHAREILLSSSSTTTSDSPDPSSGDAAVSALQQQLLLMVAR
RTQSETPQH-----------LSQDLEDSSHSSAQGKFNQEQFYKFIIFPGKWIKVWYDRL
TLLALLD---RTEDVRENVVAILLSILVSLLGFLTLNRGFCRDLWVLLFCLVMASCQYSL
LK-----------SVQPDPASPVHGHNQIIAYSRPVYFCVLCGLILLLDAGAKARPPPSY
VVYGLKFFSPESLQSVRDHLIVFLYCFPAMSLLGLFPQINTFCTYLLEQIDMLLFGGSAV
SGITSAV--YSVGRSILTAALLHVFCFSAVK-EPWSTQHIPALFSAFCG-LLVALSYHLS
RQSSDPSVF-LSFIQCKLLPKCLHQNL---EESATDPLPQRMK--------DSVKEVLKS
DLVICSAAAVLSFAVSASTVFLSLRPFLSIVLFALAGSVGLVT-HHLLPQLRKHHPWMWV
SHPVLKSKEYQQREAKDVAHLMWFERLYVWLQCFEKYLLYPAIILNALTLDAFSISNYRR
LGTHWDIFLMIT--AGMKLLRTSFCNPV--HQFVNLSFAVIFFHFDYKDISESFLLDFFM
VSIVFSK--LRDLLHKLQFVLAYVAPWQMAWGSSFHVFAQLFAVPH--------SAMLFF
QTFATSVFSTPLSPFLGSVIFITSYVRPVKFWERNYNTR---RVDNSNTRLVVQIERDPG
ND-DNNLNSIFYEHLTRTLQESLCGDLVLGRWGNYSSGDCFILASEDLNAFVHLIEIGNG
LVTFQLRGLEFQ-GTYCQQREVEAIMEGDEDDRGCCCCKPGHLPHLLSCNAAFHLRWLTW
EITRSQYILEGYSIIDNSAATMLQVFDLRRILIRYYIKSIIYYLVSSPKLLSWIKNESLL
TSLQPFAKWHHIEHDLAMFNINIDDDYVPCLQGITRASYCNVYLEWIQYCAGKRQELSK-
ALDRV

PF05041 // ENSGT00390000013164_1_Domain_0 (1866, 2097)

DSDEDSPLVTLSFALSILGRRALGTAAHNMAMSLDSFLYGLHALFKGDFRVTVRD
EWVFADMDLLHKVVVPAIR-----MSLKLHQDQFTCPDEYEDPEVLYEAIQSFEK-KVVI
CHEGDPAWRSAVLSNREELLTLRHVVDEGADEYKVIMLHRGFLSFKVIKVNKECVRGLWA
GQQQELIFLRNRNPERGSIQNNKQVLRNLINSSCDQPLGYPMYVSPLTTSYLGTHKQLQG
VWGGPVTLDSMRTWFRTRWLRMRKDCSAGQ-HSGGNIEDA-DGGVTP---SACGSNIPNG
ESQRSSTEQPRKGGAQHWASPH--GGTQRAG----RRKGRSQSVQAHSALSQRLPTLSSS
GPILESHQAFLQTSTSVHELAQRPSGSRLSLHTSAASLHSQPPPVTTTGH-LSVRERAEA
LIRSSLGSSTSSTLSFLFGKRSLSSALVISGLSAAEGGNTSDTQSSSSVNIMMGPSARAT
GHATRHFSE-PCESTDTL-EQGQLRDRRLDEAVTE-NLGVLCRR-ASQEDMGLDETASQQ
STSDEQ

------------------------------------------------------------
-------------------------MVSQVLQLLR-------QGVWAALTGGWYHDPEQS
KFTNSC--H-------LYLWLFLL-------LLP--------LALHLAFPPNAI----IV
FFYCSAVTIFFTIIKLVSYRLHLMFDKGEVIQQKPSRKEEKPNKDKEAK--GEHMTNHKN
PS--NNRQIHNGKKEEASRNLSTPPLRCSSRGQSVTSHHSSG-PLELSAQETVEDLKGVI
LLEDHPIAP-VSSTSPGIKMESLPASQAHMLETTPKSVIPVKPVATETVINGKGKERGG-
KGQ-PPLRHRSEGG-LVDKGPLKKLPHLSLSQYDLLETDVSFQPWGSENSVLI-PEPVSC
PQGSIRERVQSKSPQDSLSSS-CPQCDTIVAKPV-EEPADTSCQVD--------------
----TSCQVDLPLNQEVDSSDSEVAVTLIDTSQPGDPLNLHEPIKIVITMSSTPNS-MTD
LESSLHLKVVGTEKTDVKSDAEPTNPGAASSPNA-EQISLPVITLDLPEGGG--GGVPCP
EGNGSERTPERLK-ARVSTNQCSG--YGSREGGNAIKDHSSSS-REPWESVSRLTPDTAS
E-------SKVGKEGQTNLDPSSCKSSHEKRHARVLSVDSGTDVFLSKSSAEIVND-TEK
TMPTSKSDLEAKEGQMPNESNFLEFVSLLESINTSKMAASNPLNGSAEQNEESGLLR---
-------DNCSQEKKEEILENEKPSGHS-----SKQGKPDLQSQDHTSTSPVCTQPAKTT
AFFQGNRQRQIIYRVTSQQDSSVLQVISGPETSVQEEISVDAMHVFIDEH-GEIRSCYLK
SGNQKEGPLQPLPSNNDCLSQAREMQVSSSSTTTSESQDPSSGDPAVSALQQQLLLMVAR
RTQSETPRH-----------VSQDLEASSCSSTQGKFNREQFYKFIVFPGKWIKVWYDRL
TLLALLD---RTEDIKENVLAILLIVLVSLLGFLTLSQGFCKDMWVLLFCLVMASCQYSL
LK-----------SVQPDPASPIHGHNQIITYSRPIYFCVLCGLILLLDTGAKARHPPSY
VVYGLKLFSPVFLQSARDYLIVFLYCFPAISLLGLFPQINTFCTYLLEQIDMLFFGGSAV
SGITSAF--YSVARSFLAAALLHAVCFSAVK-EPWSMQHIPALFSAFCG-LLVALSYHLS
RQSSDPSVL-MSFIQCRLFPKFLHQNL---EESAADPLPKKMK--------DSVMDVLKW
DLIVCAVVAVLSFAVSASTVFLSLRPFLSIVLFALAGAVGFVT-HYVLPQLRKHHPWMWI
SHPILKNKEYHQREVRDVAHLMWFERLYVWLQCFEKYILYPALILNALTIDAFLISNHRR
LGTHWDIFLMIIA--GMKLLRTSFCNPV--YQFINLSFTVIFFHFDYKDISESFLLDFFM
VSILFNK--LGDLLHKLQFVLTYVAPWQMAWGSSFHVFAQLFAIPH--------SAMLFF
QMIATSIFSTPLSPFLGSVIFITSYVRPVKFWEKNYNTR---RVDNSNTRLAVQIERDPG
ND-DNNLNSIFYEHLTRTLQESLCGDLVLGRWGNYSSGDCFILASDDLNAFVHLIEIGNG
LVTFQLRGLEFR-GTYCQQREVEAIMEGDEEDRGCCCCKPGHLPHLLSCNAAFHLRWLTW
EITRTQYILEGYSILDNNAATMLQVFDLRRILIRYYIKSIIYYMVTSPKLLSWIKNESLL
KSLQPFAKWHYIERDLAMFNINIDDDYVPCLQGITRASFCNVYLEWIQHCARKRQEPSK-
T---L

PF05041 // ENSGT00390000013164_1_Domain_0 (1866, 2098)

DSDEDSPLVTLSFALCTLGRRALGTAAHNMAISLDSFLYGLHALFKGDFRITARD
EWVFADMDLLHKVVAPAIR-----MSLKLHQDQFTCPDEYEDPAVLYEAIQSFEK-KVVI
CHEGDPAWRGAVLSNKEELLTLRHVVDEGADEYKVIMLHRSFLSFKVIKVNKECVRGLWA
GQQQELIFLRNRNPERGSIQNNKQVLRNLINSSCDQPLGYPMYVSPLTTSYLGTHRQLKN
VWGGPITLDRIRTWFWIKWVRMRKDCNARQ-HSGSNIEDV-DGGGAP---TTGGNNAPSG
GSQESSTEQPRKGGAQHGVSSC--EGTQRTG----RRKGRSQSVQAHSALSQRPPMLSSS
GPILESRQTFLQTSTSVHELAQRLSGSRLSLHTSATSLHSQPPPVTTTGH-LSVRERAEA
LIRSSLGSSTSSTLSFLFGKRSFSSALVISGLSAAEGGNTSDTQSSSSVNIVMGPSARAA
SQATQHLSE-PCEPTDAT-EQGQLRDRRLAEAVAD-TLGVVCRR-ASQEDMGLDDTASQQ
SVSDEQ

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------YKCRIFPGKWIKVWFDRL
TLLALID---RTEDVGENVLGVILAILVSFLGYLVLSQGLCKDIWILQFCIVIASCQYSL
LK-----------SVQPDPASPIHGYNKIITYSRPVYFCILCGLILLLDSGAQTTNMHLP
VLYGIYLFSSNSFGIARDFVIMLVHCFPLISLLGLFPQINTFSIYFMEQIDRLIFGGSAA
LGLASAL--YALCRSSLAVAILYGFCLSAVK-EPWDIRHTPALFSAFCG-LLIALSYHLS
RQSSDPSVL-ISLIKCKSLSKVCKEHCSSSEQEQDDPLPEKMQ--------RSLKEILKS
DLIICIIVAILSYAISASTVFLSLRPFLTYVLYGLALTVGLVI-HYIIPQLRKHHPWLWI
SHPILQSKEHQEREVLDAAHLTWFEKLYLWLLCFEKYFLYPSIILNAVTVDAFSISKYKR
FGIHFDTLLITL--AGMKLLRSSFCNSL--HQYIILGFTLLFFQFDYSSISESFLINFFI
MSILFDK--LWDLLEKLQYVFTYIAPWQIAWGSSFHVFAQLLAIPH--------SAMLFL
QIFATSIFSTPLSPFLGSVIFIASYVRPVKFWEKNYNTK---RVDHSNTRLVNQIEKDAG
ND-DNNLNSIFYEHLTRSLQKSLCGDLVLGRWGNYSSGDCFILTSDYLNALVHLIEIGNG
FVTFQLRGLEFREGTYCQQREVEAITEGNEDNEDCCCCKPGHLPHMLSCNAAFNLRWLTW
EVTRTRFILEGYNVIDNNAATMLQVFDLRKVLIKYYIKSIIYFTASSPKIMKWLKDESIQ
KALQPYTRWHHVENDLAMFSINVDEDYIPCLQGITRASFCSVYLDWIQFCAN

PF05041 // ENSGT00390000013164_1_Domain_0 (1853, 2098)

KGK-----
--MKVACDEDSSLITLCFGLCILGRRVLGTAAHHMSFSLDSFLHGLHTLFKGDFRIAARD
EWVFADMDLLHTVVAPAIR-----MSLKLHQNQFACPEEYDDFSALFDAIQQFEK-KVVI
CHEGDPAWRKAVLSNREELLTLRHVVDEGTDEYKVIMLHKSYLSFKVIKVNKECVRGLWA
GQQQELIFLRNRDPERGSIQNNKQVLRNLINSSCDQPLGYPMYVSSLTISYLGTHERLRN
MWGEPISFDSIRTWFQKKWIRMRKECDTS-HHTGGNIEEMDCGG----------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------

------------------------------------------------------------
-------------------------MVSQVLQLLR-------QGVWAALTGGWYHDPEQS
KFTNSC--H-------LYLWLFLL-------LLP--------LALHLAFPPNVI----IV
FFYCSAVTIFFTIIKLVSYRLHLMFDKGEVIQQKPSRKEEKPNKDKEAK--GEHITNPKN
PS--NNRQIHNGKKEEASRNLSTPPLRCSSRGQSITSHHSSG-PLELSAQETVEDLKGVI
LSEDHPIAP-VSSTSPGIKMESLPACQAHMLETMPKSAIPVKPIATETLINGKGKERGG-
KGQ-PPLRHRSEGG-LVDKGPLKKLPHLSLSQYDLLETDISFQPWGSENSVLI-PEPVSC
PQGSVRERVQSKSPQDSLSSS-CPQCDTIVAKPV-EEPADTSCQVD--------------
----TSCQVDLPLNQEVDSSDSEVAITLIDTSQPGDPLSLHEPIKIVITMSSTPNS-MTD
LESSLHLKVVGIEKTGVKSDAEPTNPGAASSPNA-EQISIPVITLDLPEGGG--GGVPCS
EGNGSERTPERLK-ARVSTNQCSG--YGSGEGGSATKDHSSSS-REPWESASRLTPDTAS
E-------SKVGKEGLTNLDPLSCKSSHEKRHARVLSVDSGTDVFLSKSSAEIVND-TEK
TMPTSKSDLEAKEGQIPNESNFLEFVSLLESINTSKMAASNQLNGSAEQNEESGLLQ---
-------DNTSQEKKEEILENEKPSGHS-----PKQGKPDLQSQDHTSTSPVCTQPAKTT
AFFQGNRQRQIIYRVTSQQDSSVLQVISGPETSVQEEISVDAMHVFIDEH-GEIRSCYLK
SGNQKEGPLQPLPSNCDCLSQAREMQVSSSSTTTSESQDPSSGDPAVSALQQQLLLMVAR
RTQSETPRH-----------VSQDLEASSCSSTQGKFNREQFYKFIIFPGKWIKVWYDRL
TLLALLD---RTEDIKENVLAILLIVLVSLLGFLTLSRGFCKDMWVLLFCLVMASCQYSL
LK-----------SVQPDPASPIHGHNQIITYSRPIYFCVLCGLILLLDTGAKARHPPSY
IVYGLKLFSPVFLQSARDYLIVFLYCFPAISLLGLFPQINTFCIYLLEQIDMLFFGGSAV
SGITSAV--YSVARSFLAAALLHAVCFSAVK-EPWSTQHIPALFSAFCG-LLVALSYHLS
RQSSDPSVL-MSFIQCRLLPKFLHQNL---EESAADPLPKKMK--------DSVTDVLKW
DLIVCAVVAVLSFAVSASTVFLSLRPFLSIVLFALAGAVGFVT-HYLLPQLRKHHPWMWI
SHPILKNKEYHQREVRDVAHLMWFERLYVWLQCFEKYILYPALILNALTIDAFLISNHRR
LGTHWDIFLMIIA--GMKLLRTSFCNPV--YQFINLSFTVIFFHFDYKDISESFLLDFFM
VSILFSK--LGDLLHKLQFVLTYVAPWQMAWGSSFHVFAQLFAIPH--------SAVLFF
QTIATSIFSTPLSPFLGSVIFITSYVRPVKFWEKNYNTR---RVDNSNTRLAVQIERDPG
ND-DNNLNSIFYEHLTRTLQESLCGDLVLGRWGNYSSGDCFILASDDLNAFVHLIEIGNG
LVTFQLRGLEFR-GTYCQQREVEAIMEGDEDDRGCCCCKPGHLPHLLSCNAAFHLRWLTW
EITRTQYILEGYSILDNNAATMLQVFDLRRILIRYYIKSIIYYMVTSPKLLSWIKNESLL
KSLQPFAKWHYIERDLAMFNINIDDDYVPCLQGITRASFCNVYLEWIQHCARKTQEPSK-
T---L

PF05041 // ENSGT00390000013164_1_Domain_0 (1866, 2097)

DSDEDSPLVTLSFALCTLGRRALGTAAHNMAISLDSFLYGLHALFKGDFRITARD
EWVFADMDLLHKVVAPAIR-----MSLKLHQDQFTCPDEYEDPAVLYEAIQSFEK-KVVI
CHEGDPAWRGAVLSNKEELLTLRHVVDEGADEYKVIMLHRSFLSFKVIKVNKECVRGLWA
GQQQELIFLRNRNPERGSIQNNKQVLRNLINSSCDQPLGYPMYVSPLTTSYLGTHKQLKN
VWGGPITLDRIRTWFWTKWVRMRKDCNARQ-QSGGNIEDV-DGGGAP---ATGGNNAPSG
GSQESSTEQPRKGGAQHGVSSC--EGTQRTG----RRKGRSQSVQAHSALSQRPPMLSSS
GPILESRQTFLQTSTSVHELAQRLSESRLSLHTSATSLHSQPPPVTTTGH-LSVRERAEA
LIRSSLGSSTSSTLSFLFGKRSFSSALVISGLSAAEGGNTSDTQSSSSVNIVMGPSARAA
SQATRHLSE-PCEPTDAT-EQGQLRDRRPAEAVAE-TLGVVCRR-ASQEDMGLDDTASQQ
SVSDEQ

------------------------------------------------------------
-------------------------MVSQVLQLLR-------QGVWAALTGGWYHDPEQS
KFTNSC--H-------LYLWLFLL-------LLP--------LALHLAFPPNAI----IV
FFYCSAVTIFFTIIKLVSYRLHLMFDKGEVIQQKSSRKEEKPSKDKEAK--GEHVTNHKN
PS--NNRQIHNGKKEEASRHLSTPPLRCSSRGQSITSHHSSG-PLELSAQETVEDLKGVI
LSEDHPIAP-VSSTSPGIKMESLPACQAHMLETMPKSAIPVKPVATETLINGKGKERGG-
KGQ-PPLRHRSEGG-LVDKRPLKKLPHLSLSQYDLLETDVSFQPWGSENSVLI-PEPVSC
PQGSIREQVQSKSPQDSLSSS-CPQCDTIVAKPV-EEPADTSCQVD--------------
----TSCQVDLPLNQEVDSSDSEVAVTLIDTSQPGDPLSLHEPIKIVITMSSTPNS-MTD
LESSLHLKVVGIEKTGVKSDTEPTNPGAASSPNA-EQISIPVITLDLPEGGG--GGVPCP
KGNGSERTPERLK-ARVSTNQCSG--YGSGEGGSATKDHSSSS-REPWESASRLTPDTAS
E-------SKVGKEGLTNLDPLSCKSSHEKRHARVLSVDSGTDVFLSKSSAEIIND-TEK
TMPTSKSDLEAKEGQIPNESNFLEFVSLLESINTSKMAASKQLNGSAEQNEESGLLR---
-------DNTCQEKKEEILENEKPRGHS-----SKQGKPDLQSQDHTSTSPACTQPAKTT
AFFQGNRQRQIIYRVTSQQDSSVLQVISGPETSVQEEISVDAMHVFIDEH-GEIRSCYLK
SGNQKEGPLQPLPSNYDCLSQAREMQVSSSSTTTSESQDPSSGDPAVSALQQQLLLMVAR
RTQSETPRH-----------VSQDLEASSCSSTQGKFNREQFYKFIIFPGKWIKVWYDRL
TLLALLD---RTEDIKENVLAILLIVLVSFLGFLTLSRGFCKDMWVLLFCLVMASCQYSL
LK-----------SVQPDPASPIHGHNQIITYSRPIYFCVLCGLILLLDTGAKARHPPSY
IVYGLKLFSPVFLQSARDYLIVFLYCFPAISLLGLFPQINTFCIYLLEQIDMLFFGGSAV
SGITSAV--YSVARSILAAALLHVVCFSAVK-EPWSTQHIPALFSAFCG-LLVALSYHLS
RQSSDPSVL-MSFIQCRLLPKFLHQNL---EESAADPLPKKMK--------DSVTDVLKW
DLIVCAVVAVLSFAVSASTVFLSLRPFLSIVLFALAGAVGFVT-HYLLPQLRKHHPWMWI
SHPILRNKEYHQREVRDVAHLMWFERLYVWLQCFEKYILYPAVILNALTIDAFLISNHRR
LGTHWDIFLMII--AGMKLLRTSFCNPV--YQFINLSFTVIFFHFDYKDISESFLLDFFM
VSILFSK--LGDLLHKLQFVLTYVAPWQMAWGSSFHVFAQLFAIPH--------SAVLFF
QTIATSIFSTPLSPFLGSVIFITSYVRPVKFWEKNYNTR---RVDNSNTRLAVQIERDPG
ND-DNNLNSIFYEHLTRTLQESLCGDLVLGRWGNYSSGDCFILASDDLNAFVHLIEIGNG
LVTFQLRGLEFR-GTYCQQREVEAIMEGDEEDRGCCCCKPGHLPHLLSCNAAFHLRWLTW
EITRTQYILEGYSILDNNAATMLQVFDLRRILIRYYIKSIIYYMVTSPKLLSWIKNESLL
KSLQPFAKWHYIERDLAMFNINIDDDYVPCLQGITRASFCNVYLEWIQHCAWKTQEPSK-
T---L

PF05041 // ENSGT00390000013164_1_Domain_1 (1866, 1952)

DSDEDSPLVTLSFALCTLGRRALGTAAHNMAMSLDSFLYSLHALFKGDFRITARD
EWVFADMDLLHKVVAPAIR-----MSLKLHQKCVGEN-----------------------
------------------------------------------------------------
-------------PQR--------------------------------------------
---------------ISPSHRMRKDCNARQ-QSGGNIEDV-DGGGAP---TTGGNNAPSG
GSQESSAEQPRKGGAQHGVSSC--EGTQRTG----RCSGGLRTTDEVL-----------F
--GPKSRQTFLQTSTSVHELAQRLSESRLSLHTSATSLHSQPPPVTTTGH-LSVRERAEA
LIRSSLGSSTSSTLSFLFGKRSFSSALVISGLSAAEGGNTSDTQSSSSVNIVMGPSARAA
SQATWRLSE-PCEPTDAT-AQGQLCDRRLAEAVAE-TLGVVCRR-ASQEDMGLDDTASQQ
SVSDEQ

------------------------------------------------------------
-------------------------MASRVLLLLR-------QGVWAALTGGWYHDPDQS
KFTNSC--H-------LYLWLFLL-------LLP--------LALHLAFPPNAI----TV
FFYCSSVTIFFTIIKLISYRLHLMFDKGEVIQQRPSRKKEKPNKDKEAI--SDHITNHKN
TG--NNGRINNGKKEEASRTLSTPPVHGSSRGQSINSHHSSG-LLELPEQETVEDLKGVI
VSDDQPVAP-VSSTSPGMKTERLPASKGHVPETMTTSAIPVKPVVAETCISDKGKEKGG-
QGQ-SPFCHRSEGG-LVDKEAVKKVPYLSLSQYDLLETDVSFQPWGSENSVLI-PEPGNF
--ASIREQLQSKSPQDSLSSS-CPQCNTVIAKPG-REQ----------------------
----VSQQVDPPLNQEVDDSDNEVAVTLIDTSQPGDLLSLHEPIKIVITMSSTPNS-MTD
LESSLHLKVVGTEATGFTCDAEPVPPGAAGPE---KQMRIPIITLELSEGGG--GGMVCP
EGNGSDRTPERLM-VEASSNPCSG--YESGDGGDATQDHSPSP-GDPCTTPPP-TPDVVS
E-------SEGGTEVQANLDPSSCRTSQEKRHSQVLSVDSGTDVFLSKSSAEVIND-KEQ
TMPTSKSDLEAKEGQIPNESNFLEFVSLLESINTSKVVVSNQKNEPAEESKDSGLPG---
-------DNHSQEKKEEILESEKPSGPN-----AKQGKPDMQSQEHTSTSPGLTEPAKIP
TLFQGSRQRQIIYRVTSQQDSSVLQVISGPETSVQDEMSVDAMHVFIDEH-GEIKSCYLK
SGNQKEGPFQHQSSNYDGFSHAGDIQSSSSSTTTSESQDPSSGDPVVSALQQQLLLMVAR
RTQSETPRXXXX--XXXXXXXXXXXXXXXXX---------XXXXXXXXXXXXXXXXXXXX
XXXXXXX---XTEDVKENVLAVLLIVLVSLLGFLTLNRGFCKDMWVLLFCLVMASCQYSL
LK-----------SVQPDPASPIHGHNQIITYSRPIYFCVLCGLILLLDTGAKARHPPTY
IVYGLKLFSPGSLQSARDFLIVFLYCFPAISLLGLFPQINTFCIYLLEQIDMLFFGGSAV
SGMLSAV--YSVARSASAAAVLHVFCFSAVK-EPWSTQHIPALFSAFCG-LLVALSYHLS
RQSSDPSVL-LSFIQCRLLHKFLHQNL---EELAADPLPKKMK--------DSVKDILKS
DLIICSVAAILSFAVSASTVFLSLRPFLSIVLFALAGTVGFVT-HYLLPQLRKHHPWMWI
SHPVLKTKEYQQREVRDVAHLMWFERLYVWLQCFEKYILYPAIILNALTTDAFSISNYRR
LGTXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXX----XXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXFHVFAQL-AIPH--------SAMLFF
QAFATSIFSTPLSPFLGSVIFITSYVRPVKFWEKNYNTR---RVDNSNTRLVVQIEKDPG
SD-GNNLNSIFYEHLTRALQESLCGDLVLGRWGNYSSGDCFILASDYLNAFVHLIEIGNG
LVTFQLRGLEFR-GTYCQQREVEAITEGDEDDRGCCCCKPGHLLHLLSCNAAFNLRWLTW
EITRAQYILEGYSIMDNNAATMLQVFDLRRILIRYYIKSIIYYMVTSPKLFSWIKNESLL
KSLQPFAKWHYIERDLAMFNMNIDDDYVPCLQGITRASYCNVYLEWIQYCARKRQEPSK

PF05041 // ENSGT00390000013164_1_Domain_0 (1860, 2098)

-
P---LDSDEDSPLVTLSFALCILGRRALGTAAHNMALSLDSILYGLHTLFKGDFRITAQD
ECVFADIDLLHKVVAPALR-----MSLKLHQDQFTCPDEYEDPVVLYEAIQSFEK-KVVI
CHEGDPAWRGAMLANKEELLTLRHVVDEGTDEYKVIMLHRSFLSFKVIKVNRECVRGLWA
GQQQELIFLRNCNPERGSIQNHKQVLRNLISSSCDQPLGYPMYVSPLTTSYLGTHRQLKN
VWSGPVTLDSVRAWFRAKWLRVRKDCDAAGQPGAGNSLDA-DGGGAP---PVGGSSAPSG
ESRESSSEQPRKDGSRHRSPP---EGTRTTG----RRKGRTQSVQAPRVLSQTPPIPRSS
GPTVDSHPAFLQTSTSVHELARRLSGSRLSPCTSAASLRSQPPPAPAAGH-LSVRERAEA
LIRSSLGSSTSSTLSFLFGKRSFSSVLVISGLSAAEGGNTSDTQSSSSVNITLGPSARTT
SQPARHFSE-PCEPTEAT-EQGLLRDHHVA-----ENLRVMCRR-ASQEDMGLDDTASQQ
SASDEQ

------------------------------------------------------------
-------------------------MGSQVLQLLR-------QGVWAALTGGWYHDPDQS
KFTNSC--H-------LYLWLFLF-------LLP--------LALHLAFPPDAI----TV
FLYCSSVTIFFTVIKLVSYRLHLMFDKGEVIQQRPSGKKEKPRKDKEAN--GDHITNHRN
PRISNNGQINSGKKEA-DRSLSTPPLHGSSGGQSINSHHSSG-LLDLPAQETVEDLKGVV
LSDDQPMAP-VSSTSPAIKAESLPASKAPVLGAVTTSAIPLKPVVAETCISDQGKERGG-
RGQ-PPFHHRSEGG-LVDKETVKKLPYLSLSQYDLLETDVSVQPWGSENSVLI-PEPGHY
--ASIRDKLQNKSPQDSLSSS-CPQCNTVIARPV-QGQ----------------------
----VSQQVDSTLNQDVGDSDSEVAVTLIDTSQPGDPLSLHEPIRIVITMSSTPNS-MTD
LESSLHLKAVGTQPSGFQADAEPAPPGAASPLNV-EQMRIPVITFQLSEDAG---GMVCP
ESSGSGRTPERLT-VEASSNPCSG--YESGEGGSATQDHSPSP-GDHCATP-P-TPNMVS
E-------SEVGMEAQANLDPSSCRTSQEKRHARVLSVDSGTDVFLSKSSAEIIND-KEQ
TMPTSKSDLEAKEGQVPNESNFLEFVSLLESINTSKVVVSNQRNEPTEQNKDSRLPA---
-------DNCSQEKKEEILESEKPSGPI-----AKQGKPDVQSQDHTSTSPGLTEPAKIP
TLFQGNRQRQIIYRVTSQQDSSVLQVISGPETSVQDEMSVDAMHVFIDEH-GEIKSCYLK
SGNQKEGPFQHQPSNYEGFSHAGDLQISSSSTTTSESQDPSSGDPAVSALQQQLLLMVAR
RTQSETPRH-----------LSQDLEDSSCSSTQGKFNREQFYKFIIFPGKWIKVWYDRL
TLLALLD---RTEDVKENVLAVLLIILVSLLGFLTLNQGFCKDIWTLLFCLIMASCQYSL
LK-----------SVQPDPASPIHGHNQIITYSRPIYFCVLCGLILLLDTGAKARHPPTY
IVYGLKLFSPESLQWARDLLIVFLYCFPAISLLGLFPQINTFCIYLLEQIDMLFFGGSAV
SGLPSAA--YSVARSASAAALLHVFCFSAVK-EPWSTQHIPALFSAFCG-LLVALSYHLS
RQSSDPSVL-LSFIHCKLFHKFLHQNL---EELASDPLPMKMK--------DSVKDILKS
DLIICLVAAVLSFAVSASTVFLSLRPFLSIVLFALAGAVGFVT-HYLLPQLRKHHPWMWI
SHPILKSREYQQREVRDVAHLMWFERLYVWLQCFEKYILYPAIILNALTTDAFSISNYRR
LGTHWDIFLMVI--AGMKLLRTSFCNPV--HQFTHLGFTVIFFHFDYKDISESFLLDFFM
VSILFSK--LGDLLHKLQFVLTYVAPWQMAWGSSFHVFAQLFAIPH--------SAMLFF
QTFATSIVSTPLSPFLGSVIFITSYVRPVKFWEKNYNTR---RVDNSNTRLVVQIEKDSG
SD-GNNLNSIFYEHLTRALQESLCGDLILGRWGNYSSGDCFILASDYLNAFVHLIEIGNG
LVTFQLRGLEFR-GTYCQQREVEAIMEGDEDDRGCCCCKPGHLPHLLSCNAAFNLRWLTW
EITRTQYILEGYSIMDNNAATMLQVFDLRRILIRYYIKSIIYYMVTSPKLFSWIKNESLL
KTLQPFAKWHYIERDLAMFNMNIDDDYVPCLQGITRASYCNVYLEWIQYCAQKRQEPSK-
P---L

PF05041 // ENSGT00390000013164_1_Domain_0 (1866, 2098)

ESDEDSPLVTLSFALCILGRRALGTAAHNMALSLDSFLYGLHALFKGDFRITARD
EWVFADIDLLHKVVVPALR-----MSLKLHQDQFTCPDEYEDPAVLYEAIQSFEK-KVVI
CHEGDPAWRGAVLANKEELLTLRHVVDEGTDEYKVLMLHRSFLSFKVIKVNRECVRGLWA
GQQQELIFLRNRNPERGSIQNNKQVLRNLINSSCDQPLGYPMYVSPLTTSYLGTHRQLKN
IWSGPVTLDSIRAWLRTKWLRVRKDCDAAGQPGAGNTEDM-DAGGAP---PAGGNSAPSG
ESRESSAEQPRKDGSRHWSP-R--EGTRRPG----RRKGRSQSVQAHRALSQTPPVLRAS
GPVAGSRPTFLQTSTSVHELAPRRSGSRLSLCPSAASLHSQPPAAPPAGP-LSVRERAEA
LLRSSLGSSTSSTLSFLFGKRSFSSALVISGLSAAEGGNTSDTQSSSSVNIALGPSARAA
SQSTRHFSE-PCEHTEVT-EQGLLQDHHVA-----KNLGVMCRR-ASQEDMGLDDTASQQ
SASDEQ

------------------------------------------------------------
-------------------------MVSQVLQLLR-------QGVWAALTGGWYHDPEQS
KFTNSC--H-------LYLWLFLL-------LLP--------LALHLAFPPNAI----IV
FFYCSAVTIFFTIIKLVSYRLHLMFDKGEVIQQKPSRKEEKPNKDKEAK--GEHITNPKN
PS--NNRQIHNGKKEEASRNLSTPPLRCSSRGQSITSHHSSG-PLELSAQETVEDLKGVI
LSEDHPIAP-VSSTSPGIKMESLPACQAHMLETMPKSAIPVKPIATETLINGKGKERGG-
KGQ-PPLRHRSEGG-LVDKGPLKKLPHLSLSQYDLLETDISFQPWGSENSVLI-PEPVSC
PQGSVRERVQSKSPQDSLSSS-CPQCDTIVAKPV-EEPADTSCQVD--------------
----TSCQVDLPLNQEVDSSDSEVAVTLIDTSQPGDPLSLHEPIKIVITMSSTPNS-MTD
LESSLHLKVVGIEKTGVKSDTEPTNPGAASSPNA-EQISIPVITLDLPEGGG--GGVPCP
EGNGSERTPERLK-ARVSTNQCSG--YGSGEGGSATKDHSSSS-REPWESASRLTPDTAS
E-------SKVGKEGLTNLDPLSCKSSHEKRHARVLSVDSGTDVFLSKSSAEIVND-TEK
TMPTSKSDLEAKEGQIPNESNFLEFVSLLESINTSKMAASNQLNGSAEQNEESGLLQ---
-------DNTSQEKKEEILENEKPSGHS-----PKQGKPDLQSQDHTSTSPACTRPAKTT
AFFQGNRQRQIIYRVTSQQDSSVLQVISGPETSVQEEISVDAMHVFIDEH-GEIRSCYLK
SGNQKEGPLQPLPSNCDCLSQAREMQVSSSSTTTSESQDPSSGDPAVSALQQQLLLMVAR
RTQSETPRH-----------VSQDLEASSCSSTQGKFNREQFYKFIIFPGKWIKVWYDRL
TLLALLD---RTEDIKENVLAILLIVLVSLLGFLTLSQGFCKDMWVLLFCLVMASCQYSL
LK-----------SVQPDPASPIHGHNQIITYSRPIYFCVLCGLILLLDTGAKARHPPSY
IVYGLKLFSPVFLQSARDYLIVFLYCFPAISLLGLFPQINTFCIYLLEQIDMLFFGGSAV
SGITSAV--YSVARSFLAAALLHAVCFSAVK-EPWSTQHIPALFSAFCG-LLVALSYHLS
RQSSDPSVL-MSFIQCRLLPKFLHQNL---EESAADPLPKKMK--------DSVTDVLKW
DLIVCAVVAVLSFAVSASTVFLSLRPFLSIVLFALAGAVGFVT-HYLLPQLRKHHPWMWI
SHPILKNKEYHQREVRDVAHLMWFERLYVWLQCFEKYILYPALILNALTIDAFLISNHRR
LGTHWDIFLMII--AGMKLLRTSFCNPV--YQFINLSFTVIFFHFDYKDISESFLLDFFM
VSILFSK--LGDLLHKLQFVLTYVAPWQMAWGSLFHVFAQLFAIPH--------SAVLFF
QMIATSIFSTPLSPFLGSVIFITSYVRPVKFWEKNYNTR---RVDNSNTRLAVQIERDPG
ND-DNNLNSIFYEHLTRTLQESLCGDLVLGRWGNYSSGDCFILASDDLNAFVHLIEIGNG
LVTFQLRGLEFR-GTYCQQREVEAIMEGDEDDRGCCCCKPGHLPHLLSCNAAFHLRWLTW
EITRTQYILEGYSILDNNAATMLQVFDLRRILIRYYIKSIIYYMVTSPKLLSWIKNESLL
KSLQPFAKWHYIERDLAMFNINIDDDYVPCLQGITRASFCNVYLEWIQHCARKTQEPSK-
T---L

PF05041 // ENSGT00390000013164_1_Domain_0 (1866, 2097)

DSDEDSPLVTLSFALCTLGRRALGTAAHNMAISLDSFLYGLHALFKGDFRITARD
EWVFADMDLLHKVVAPAIR-----MSLKLHQDQFTCPDEYEDPAVLYEAIQSFEK-KVVI
CHEGDPAWRGAVLSNKEELLTLRHVVDEGADEYKVIMLHRSFLSFKVIKVNKECVRGLWA
GQQQELIFLRNRNPERGSIQNNKQVLRNLINSSCDQPLGYPMYVSPLTTSYLGTHKQLKN
VWGGPITLDRIRTWFWTKWVRMRKDCNARQ-QSGGNIEDV-DGGGAP---ATGGNNAPSG
GSQESSAEQPRKGGAQHGVSSC--EGTQRTG----RRKGRSQSVQAHSALSQRPPMLSSS
GPILESRQTFLQTSTSVHELAQRLSESRLSLHTSATSLHSQPPPVTTTGH-LSVRERAEA
LIRSSLGSSTSSTLSFLFGKRSFSSALVISGLSAAEGGNTSDTQSSSSVNIVMGPSARAA
SQATRVRGW-TGLTRTGW--GGGMGS-WPEHGTCL-AFPPFCLQNPLPSSVGFPE-----
------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------AFPANSV----TV
FVYCSSVTVFFTVIKVISYRLHLMFDKGEVIQQKLSRKNGRQCKDTEVE--KEE-VVQSS
NC--SNNSGDH-VVGETSQNDSTQTIPDSSRAQDPHSQDSPG-ATNLPTRETIEDLRGVM
VLEDQATPP-VSSTSPCIKADILPVSTTSGSGA-TTSAIATKP-AVETFPGDGVNEKGV-
SGQ-PCGHHGSQD-ILVDRDTVKNFSNISSSQGDILRTGVSSEPWDSENSV-I-SDHLSN
PTNHKREKLPDESPQTGFTSN-CPQCNAIATKEH-EQ-ME--------------------
----SSCNAGN-SHEDLDCSDSETAVAVVDNSLPGDQ--LCEPIKIVITMSTTPNTTLSD
LPGSVHLQALESERTSSALDSGVVRTGWSS-QQTNEQLRIPVITFDLSDDS---KAKPCS
EVSESDRTPEILR-AEMSSNQCSG--YESGDAVKELSN----PANTPLETNTCS-----D
PNQNVQTVDVSSKEDLHNLDPQSCRTAHEKRHMRVLSVDSGTDVLLSKNFVE-ASD-KEK
TLPTSKSDLEAKEGQMSNESNFLEFVSLLESINTSKMKTSNQSTVKMETTKENGLVG---
-------DSQMTERKEEMVGTEKHCEQL-----PKQERSDVQSQDRASTSPVLPESAKFA
ALYQGSRQRQIIYRVTSQQDSSVLQVISGPEASVQDELSVDAMHVFIDEN-GEIRSCYLK
AGCQKEGNFRHQLSNCDCMSNAHEIQFSSSSTTTSESQEPSSGDQAASALQQQLLLMVAR
RTLSENPR-----------QPSQDPEDSSCSSAQRKLNR-QFYRFVIFPGKWIKVWYDRL
TLLALLD---RTEDIKENVFAVLLVVLVSLLGFLTLNQGFCKDIWVLLFCLVMASCQYSL
LK-----------SVQPDPASPIHGHNKIIVYSRPVYFCILCGLILLLDAGSKDTNPPVY
TMYGLKLFSPRSLQSARDHVIVFLYCFPAISLLGLFPQINTFCIYLLEQIDMLLFGGSAA
AGFVSAL--YSISRSFVVLIVLYAFCFSAVK-EPWDAQHIPALFSAFCG-LLVALSYHLS
RQSSDPSVL-MSLIQCKYVPHYLRQRF---EDSSEDPLPEKMR--------ESVKEILKS
DLIVCTAAAVLSFAVSASTVFLSLRPFLSIVLFALAWTVGFVT-HYILPQLRKHHPWLWI
SHPILKSKEHQQREVRDAAHLMWFERLYVWLQCFEKYILYPAIILNALTIDAFSISKYKK
LGTHCDIILITV--AGMKLLRSSFCNPI--NQFVTLSFTVIFFRFDYRDISENFLLDFFM
MSIVFHK--LWDLLQKLQFIMTYIAPWQIAWGSSFHVFAQLFAIPH-------NSAMLFF
QTLAASVFSTPLSPFLGSVIFIASYARPVKFWEKNYNTK---RSDHSNTRLAIQIEKDAG
ND-DNNLNSIFYEHLTRSLQESLCGDLILGRWGNYNTGDCFILASDYLNAFVHLIEIGNG
LVTFQLRGLEFR-GTYCQQREVEAITEGDEDNEGCCCCKPGHLPHLLSCNAAFNLRWLTW
EITRTQYILEGYSIIDNNAATMLQVFDLRRILIRYYIKSIIYFTASSPKILNWIKDESIQ
KILQPYAKWHYIERDLAMFNVNIDEDYVPCLQGITRASFCSVYLDWIQFCARKRVEES--
-

PF05041 // ENSGT00390000013164_1_Domain_0 (1862, 2098)

-VHLDSDEDSPLVTLSFALCILGRRALGTASHNMAISLDSFLYGLHALFKGDFRIAAKD
EWVFADMDLLHKVVAPAIR-----MSLKLHQDQFTCPDEYEDPAVLYEAIQSFEE-KVVI
CHEGDPAWRSAVLSNREELLTLRHVVDEGADEYKVIMLHKSYLSFKVIKVNKECVRGLWA
GQQQELIFLRNRNPERGSIQNNKQVLRNLINSSCDQPLGYPMYVSPLTTSYLGTHSQLRN
IWGGPVSLDNIKKWFKSKWLRMRKDCHAAAHHERGNVEEVDSGGGSSSSN------NSTG
NSSQSSSSQPTRNGTPQLQTS-SQEVHQRAG----RRKPRSQSVQAHTALNQRPPASSHS
GPIVESRQPFIQTSTSAHEIAQRLSSSQLSFHNSATSVFSQSPAVPVAGQ-LTVQDRAAA
MLRSSLASSTSSTLSLLFGKRSFSSALVISGLSAADGGNTSDTQSSSSMNIAMGPSARAA
SQAARQVTE-TCEAADAP-EARPQREAGPAHALFM-SRNLECRR-ASQEDMALEDTASQQ
SLSEEQ

MEGLWAGAGRSLWSILRAAASEHHGKILPPSDMAPTCPVAAAGSGAAIRGXXXXXXXXXX
XXXXXXXXXXGSGQ-RGACWPRRAGMGSQVLQLLR-------QGVWAALTGGWYHDPDQS
KFTNSC--H-------LYLWLSLL-------LLP--------LALHLAFPPDAI----TV
FFYCSSVTIFFTIIKLISYRLHLMFDKGEVIQRRPPGKKEKQSKDKEAN--GDHITNHRN
P--SNNGQINSGKKEA-DRTLSTPPLHGSSGRQSINSHHSSG-LLDLPAQETVEDLKGVI
LSDDQPIAP-VPSTSPGIKTESLPASKAPVLGTITTSAIPLKPVVAETCIGDQGKERGS-
RGQ-PPFHHRSEGG-LVDKETVKKLPCLSLSQYDLLETDVSVQPWGSENSVLI-PEPGHY
--ASIRDKLQSKSPQDSLSSS-CPQCNTVIVRPG-QEQ----------------------
----VSQQVDSTLNQDMGNSDSEVAVTLIDTSQPGDPLSLHEPIRIVITMSSTPNS-MTD
LESSLHLKAVGTQPSGFQADAEPAPPGAAGPPNV-EQMRIPVITFQLSEDAG---GMVCP
ESNGSGRSPERLT-VEASSNPCSG--YESGEGGSATQDHSPSP-GDHCATPPP-TPNMIS
A-------SEVGMEAQANLDPSSCRTSQEKRHARVLSVDSGTDVFLSKSYTEIIND-KEQ
TMPTSKSDLEAKEGQVPNESNFLEFVSLLESINTSKVVVSNQRNEPTEQNKDSRLPA---
-------DNCSQEKKEEILESEKPSGPI-----ATQGKPDVQSQDHTSTSPGLTEPAKIP
TLFQGNRQRQIIYRVTSQQDSSVLQVVSGPETSVQDEMSVDAMHVFIDEH-GEIKSCYLK
SGNQKEGPFQHQPSNYEGFSHAGDLQISSSSTTTSESQDPSSGDPAVSALQQQLLLMVAR
RTQSETPRRISP--TKRNTHLSRDLEDSSSSSTQGKFNREQFYKFIIFPGKWIKVWYDRL
TLLALLD---RTEDVKENVLAVLLIILVSLLGFLTLNQGFCKDIWALLFCLIMASCQYSL
LK-----------SVQPDPASPIHGHNQIITYSRPIYFCVLCGLILLLDTGAKARHPPTY
TVYGLKLFSPGSLQWARDLLIVFLYCFPAISLLGLFPQINTFCIYLLEQIDMLFFGGSAV
SGLLSAV--YSVARSASAVAVLHVFCFSAVK-EPWSTQHIPALFSAFCG-LLVALSYHLS
RQSSDPSVL-LSFIQCKLLHKFLHQNL---EELASDPLPMKMK--------DSVKDILKS
DLIICSVAAVLSFAVSASTVFLSLRPFLSMVLFALAGAVGFVT-HYLLPQLRKHHPWMWI
SHPILKNREYQQREVRDVAHLMWFERLYVWLQCFEKYILYPAIILNALTTDAFSISNYRR
LGTHWDIFLMVI--AGMKLLRTSFCNPV--HQFTHLGFTVIFFHFDYKDISESFLLDFFM
VSILFSK--LGDLLHKLQFVMTYVAPWQMAWGSSFHVFAQLFAIPH--------SAMLFF
QTFATSIVSTPLSPFLGSVIFITSYVRPVKFWEKNYNTR---RVDNSNTRLVVQIEKDPG
SD-GNNLNSIFYEHLTRALQESLCGDLILGRWGNYSSGDCFILASDYLNAFVHLIEIGNG
LVTFQLRGLEFR-GTYCQQREVEAITEGDEDDRGCCCCKPGHLPHLLSCNAAFNLRWLTW
EIARTQYILEGYSIMDNNAATMLQVFDLRRILIRYYIKSIIYYMVTSPKLFSWIKNESLL
KTLQPFAKWHYIERDLAMFHMNIDDDYVPCLQGVTRASYCNVYLEWIQYCAQKRQEPSK-
P---L

PF05041 // ENSGT00390000013164_1_Domain_0 (1866, 2098)

ESDEDSPLVTLSFALCILGRRALGTAAHNMALSLDSFLYGLHALFKGDFRITARD
EWVFADIDLLHKVVVPALR-----MSLKLHQDQFTCPDEYEDPAVLYEAIQSFEK-KVVI
CHEGDPAWRGAVLANKEELLTLRHVVDEGTDEYKVLMLHRSFLSFKVIKVNRECVRGLWA
GQQQELIFLRNRNPERGSIQNNKQVLRNLINSSCDQPLGYPMYVSPLTTSYLGTHRQLKN
VWSGPLTLDSIRAWLRTKWLRVRKDCDAAGQPGAGNTEDV-DAARAP---PAGGSSAPSG
ESRESSAEQPRKDGSRHWSP-R--EGTRRPG----RSKGRSQSVQAHRALSQTPPVLRAS
GRLVHQLHPQLPV--WQEELL-QRPGHFRAVCCRGGQHQ---------------------
------------------------------------------------------------
------------------------------------------------------------
------

------------------------------------------------------------
-------------------------MVSQALQLLR-------QGVWAALTGGWYHDPEQS
KFTNSC--H-------LYLWLFLL-------LLP--------LALHLAFPPNAI----TV
FFYCSSVTIFFTIIKWVSYRLHLMFDKGEVIQQKPSRKKEKANKDKEAN--TDRITNDKN
PS--NNGQINNSKKEEAGPPLSTPPLHGSSRGQSITSHHSSG-LLELPAQETVEDLKGVI
LSDDQPIAP-VSSTSPGIKTESLPASKISVLETTTTSAIPMRPVMAETLIDDKGKERRG-
KGQ-PPFHHRSEGG-LVDKETVKRFPHLSLSQYDLLETDISFHPWGSENSVLI-PEPGNY
AQGSIREQLPSKSLQDSLSSS-CPQCDTVIANPR-CEQLD--------------------
----ICQQVGPPLGQDMDYSDSEVAVTLIDTSQPGDPRSLHEPIKIVITMSSTPTS-MTD
LESSLHLKVIGTERTGIKSDAEPATLGAAGPPDV-EQMRIPVITLELSEDEG--GGGMCP
ESSGSDRTPERLM-VEASSNQCSGI---------ATKDGSPSP-RDHCGTTPPHTPHVVS
A-------SEVGVEGQAHLDPSSCRTSQEKRHARVLSVDSGTDVFLSKSSAEIIHD-KEK
TIPTSKSDLEAKEGQIPNESNFLEFVSLLESINTSKVVASGQRNEPAEQKKDSELLG---
-------DNYSQEKKEEILESEKPSGCY-----ARQGKPDMQSQDHTSTSPGLTEPTKIP
TFFQGNRQRQIIYRVTSQQDSSVLQVISGPETSVQDEMSVDAMHVFIDEH-GEIKSCYLK
SGNQKEGPFQHQPSNYDGFSHARDIQISSSSTTTSESQEPSSGDPAVSALQQQLLLMVTR
RTQPETPRH-----------LSQDLEDSSSSSTPGKFNREQFYKFIIFPGKWIKVWYDRL
TLLALLD---RTEDVKENVLAVLLIVLVSLLGFLTLNRGFCKDMWALLFCLVMASCQYSL
LK-----------SVQPDPASPIHGHNQIITYSRPVYFCVLCGLILLLDIGAKARHPPTY
VVYGLKLFSPRSLQSARDLLIVFLYCFPAISLLGLFPQINTFCIYLLEQIDMLFFGGSAV
SGMLSAV--YSVARSASAAAVLHVFCFSAVK-EPWSTQHIPALFSAFCG-LLVALSYHLS
RQSSDPSVL-LSLLQCRLFHKFLHQNL---EELAADPLPRKMK--------ESVKDILKS
DLVICSLAAVLSFAVSASTVFLSLRPFLSVVLFALAGAVGFVT-HYMLPQLRKHHPWMWI
SHPILKNKEYQQREVTDVAHLMWFEKLYVWLQCFEKYVLYPAIILNALTLDAFSISNYRR
LGTHWDIFLMVI--AGMKLLRTSFCNPV--HQFTHLGFTVIFFHFDYKDISESFLLDFFM
VSILFSK--LGDLLQKLQFVMTYVAPWQMAWGSSFHVFAQLFAIPH--------SAMLFF
QTFATSIFSTPLSPFLGSVIFITSYVRPVKFWEKNYNTR---RVDNSNTRLVVQIEKDPG
NN-DNNLNSIFYEHLTRALQESLCGDLVLGRWGNYSSGDCFILASDYLNAFVHLIEIGNG
LVTFQLRGLEFR-GTYCQQREVEAIMEGDEDDRGCCCCQPGHLPHLLSCNAAFNLRWLTW
EITRTQYILEGYSIMDNNAATMLQVFDLRRILIRYYIKSIIYYMVTSPKLLSWIKNESLL
KSLQPFTKWHYIERDLAMFNMNIDDDYVPCLQGITRASYCNVYLEWIQYCAHKRQEPSK-
N---L

PF05041 // ENSGT00390000013164_1_Domain_0 (1866, 2097)

DSDEDSPLVTLSFALCILGRRALGTAPT---TCLDSFLYGLHALFK---------
-----DIDLLHKVVAPALK-----MSLKLHQDQFTCPDEYEDPAVLYEAIQSFER-KVVI
CHEGDPAWRGAVLANKEELLTLRHVVDEGADEYKVIMLHRSFLSFKVIKVNRECVRGLWA
GQQQELIFLRNRNPERGSIQNNKQVLRNLINSSCDQPLGYPMYVSPLTTSYLGTHRQLKS
VWSGPVTWDGIRAWFRTKWLRMRKECDAGT-QGAGHIEDV-DGGGAR---PAGGSSAPSG
ESRESSSEQPRKEGARHWSPCE--E-AQRAGRGPPVRKGRSQSVQAHRALSQTPPAPRSA
GPVVDSHPAFLQTSTSVHELAQRLSGSRLSLRTSAASLHSQPPPVITTGH-LSVRERAEA
LLRSSLGSSTSSTLSFLFGKRSFSSALVISGLSAAEGGNTSDTQSSSSVNITMGPSARAT
SQPTRHFSE-PCEPTEAT-EQGPLGDRPLA----E-SLEVMCRR-ASQEDMGLDDTASQQ
SASDEQ

------------------------------------------------------------
-------------------------MVSQVLQLLR-------QGVWAALTGGWYHDPEQS
KFTNSC--H-------LYLWLFLL-------LLP--------LALHLAFPPTMI----TA
LFYCSSVTVLFTIIKVVSYRLHLMFDKGEVIQQRSPRKMEKPKKDREAN--SEHATNPKH
LS--NTRPIHSSKKEEMGGGVPTPPLHCSSHGQSLSSHRSSG-PLELPVQETVEDLKGVI
LSKDHPGAP-MSSTSPGIKTESLPASQVCLPEPMPRSAGLTNPAVPEALINEQRRGREG-
QGQ-CPPCHRSEGG-LVDREDLKKLPRLSLSQYDLLETDVSFQPWGSENSVLI-PEPVTC
PQGSIREQLQSRSPQDSLSNS-CPQCHTVMAKPA-ERLAG--------------------
----TSSQVDLPFSQGINSSDSEVTVTLIDTSQPGDPLSLHEPIKIVITMSS--NS-MTE
EGSCLHLKVTGTEQVGPRSHMEPASPRGASPPKA-EHIQIPVITLELSEDGG--GGVTGP
EGHGSQRSPDRLRVE--ASDQCSS-----EEAGRATEACT-----------QASTPPLAS
E-------AEGEGDSQASLDPASDKGSHEKRHARVLSVDSGTHVFLSRSSMDVVSD-KEK
TIPTSKSDLEAKEGQIPNESNFLEFVSLLESINTSKVVTSTQLKGSQ-------------
----CFSDHYSQGKKEEILEKKTLTGED-----SKPEKSDLQSQDHAGTSPVFTPPAKAA
ALFQGNRQRQIIYRVTSQQDSSVLQVISGPETSVQEEISVDAMHVFIDEH-GEIRSCYLK
SGNQKEGSFQHPVSNEDCASQAREVHLSSSSTSTCESPDPSSGDPAVSALQQQLLLMVAR
RTRSEIPR-----------LVSQDLEDSSCSSAPGKFNREQFYKFIIFPGKWIKVWYDRL
TLLALLD---RTEDVKENVLAIVLSVLVSLLGFLTLNRGFCRDLWVLLFCVVMASCQYSL
LK-----------A-RPHPALTLPGHNQIITYSRPIYFCVLCGLVLLLDGEAKSRHPPHY
IVYGLKLFSPESLQTARDYLIVFLYCFPAISLLGLFPQINTFCTYLLEQIDMLLFGGSAV
SGILSAL--YSVGRSILAAALLHVLCFSAVK-EPWSTQHIPALFSAFCG-LLVASSYHLS
RQSSDPSVL-LSFFQCRFFPKFLHPSL---EESSTDPLPQKMK--------DSVKDVLRS
DLVVCSVVAVLSFAVSASTVFLSLRPFLSVVLFALAGAVGLIT-HHLLPQLRKHHPWMWV
SHPVLKNKEYKQREVRDVAHLMWFERLYVWLQCFEKYILYPAIILNALTIDAFSISNYRR
LGTHWDIFLMII--AGMKLLRTSFCNPV--HQFINLSFTVIFFHFDYKDFSESFLLDFFM
VSILFSK--LGDLLHKLQFVLAYVAPWQMAWGSSFHVFAQLFAIPHIL-----------S
RSLFTPIFSTPLSPFLGSVIFITSYARPVKFWEKNYNTR---RVDNSNTRLAVQIEKDPG
GD-DNNLNSIFYEHLTRTLQESLCGDLVLGRWGNYSSGDCFILASDDLNAFVHLIEIGNG
LVTFQLRGLEFR-GTYCQQREVEAIMEGDEEDRGCCCCQPGHLPHLLSCNAAFRLRWLTW
EVARTQYILEGYSIIDNNAATMLQVFDLRRVLIQYYIKSIIYYMVASPKLLSWVKNDSLL
KSLQPFAKWHHIERDLAMFNINIDDDYVPCLQGITRASYCNVYLEWIQYCAGKRQEPSK-
T---L

PF05041 // ENSGT00390000013164_1_Domain_0 (1866, 2097)

DSDEDSPLVTLSFALCILGRRALGTAAHNMAMSLDSFLYGLHALFKGDFRITVRD
EWVFADMDLLHKVVVPAIR-----MSLKLHQDQFTCPDEYEDPAVLYGAIQSFEQ-KVVI
CHEADPAWRGAVLSNREELLTLRHVVDEGTDEYKVIMLHRGFLSFKVIKVNKECVRGLWA
GQQQELIFLRNRNPERGSIQNNKQVLRNLINSSCDQPLGYPMYVSPLTTSYLGTHRQLRN
VWGRPVMLDSLRTWFQARWLSMRKDCNTG-QRSGGAIEDLDGGGAPSG------------
---DSSLEQPQKGGTQPWVSPCK--GAQRTG----HRKGRSQSVQVPSALSQRLPVLSSS
GPIVESRQAFLQTSTSVHELAPRPSGSRLSLHTSTTSLHSQPPPGTTTGH-LSVRERAEA
LIRSSLGSSTSSTLSFLFGKRSFSSALVISGLSAAEGGNTSDTQSSSSVNIVMGPSARAA
GHATRHFSE-PCDPTEAA-EQGQLRDRRLAEAVAE-NLRVMCRR-ASQEDMGLDDTASQQ
SASDEQ

------------------------------------------------------------
-------------------------MVSQVLQLLR-------QGVWAALTGGWYHDPEQS
KFTNSC--H-------LYLWLFLL-------LLP--------LALHLAFPPNAI----IV
FFYCSAVTIFFTIIKLVSYRLHLMFDKGEVIQQKPSRKEEKPNKDKEAK--GEHITNPKN
PS--NNRQIHNGKKEEASRNLSTPPLRCSSRGQSITSHHSSG-PLELSAQETVEDLKGVI
LSEDHPIAP-VSSTSPGIKMESLPACQAHMLETMPKSAIPVKPIATETLINGKGKERGG-
KGQ-PPLRHRSEGG-LVDKGPLKKLPHLSLSQYDLLETDISFQPWGSENSVLI-PEPVSC
PQGSVRERVQSKSPQDSLSSS-CPQCDTIVAKPV-EEPADTSCQVD--------------
----TSCQVDLPLNQEVDSSDSEVAVTLIDTSQPGDPLSLHEPIKIVITMSSTPNS-MTD
LESSLHLKVVGIEKTGVKSDAEPTNPGAASSPNA-EQISIPVITLDLPEGGG--GGVPCP
EGNGSERTPERLK-ARVSTNQCSG--YGSGEGRSATKDHSSSS-REPWESASRLTPDTAS
E-------SKVGKEGLTNLDPLSCKSSHEKRHARVLSVDSGTDVFLSKSSAEIVND-TEK
TMPTSKSDLEAKEGQIPNESNFLEFVSLLESINTSKMAASNQLNGSAEQNEESGLLQ---
-------DNTSQEKKEEILENEKPSGHS-----PKQGKPDLQSQDHTSTSPACTQPAKTT
AFFQGNRQRQIIYRVTSQQDSSVLQVISGPETSVQEEISVDAMHVFIDEH-GEIRSCYLK
SGNQKEGPLQPLPSNCDCLSQAREMQVSSSSTTTSESQDPSSGDPAVSALQQQLLLMVAR
RTQSETPRH-----------VSQDLEASSCSSTQGKFNREQFYKFIIFPGKWIKVWYDRL
TLLALLD---RTEDIKENVLAILLIVLVSLLGFLTLSQGFCKDMWVLLFCLVMASCQYSL
LK-----------SVQPDPASPIHGHNQIITYSRPIYFCVLCGLILLLDTGAKARHPPSY
IVYGLKLFSPVFLQSARDYLIVFLYCFPAISLLGLFPQINTFCIYLLEQIDMLFFGGSAV
SGITSAV--YSVARSFLAAALLHAVCFSAVK-EPWSTQHIPALFSAFCG-LLVALSYHLS
RQSSDPSVL-MSFIQCRLLPKFLHQNL---EESAADPLPKKMK--------DSVTDVLKW
DLIVCAVVAVLSFAVSASTVFLSLRPFLSIVLFALAGAVGFVT-HYLLPQLRKHHPWMWI
SHPILKNKEYHQREVRDVAHLMWFERLYVWLQCFEKYILYPALILNALTIDAFLISNHRR
LGTHWDIFLMIIA--GMKLLRTSFCNPV--YQFINLSFTVIFFHFDYKDISESFLLDFFM
VSILFSK--LGDLLHKLQFVLTYVAPWQMAWGSSFHVFAQLFAIPH--------SAVLFF
QTIATSIFSTPLSPFLGSVIFITSYVRPVKFWEKNYNTR---RVDNSNTRLAVQIERDPG
ND-DNNLNSIFYEHLTRTLQESLCGDLVLGRWGNYSSGDCFILASDDLNAFVHLIEIGNG
LVTFQLRGLEFR-GTYCQQREVEAIMEGDEDDRGCCCCKPGHLPHLLSCNAAFHLRWLTW
EITRTQYILEGYSILDNNAATMLQVFDLRRILIRYYIKSIIYYMVTSPKLLSWIKNESLL
KSLQPFAKWHYIERDLAMFNINIDDDYVPCLQGITRASFCNVYLEWIQHCARKTQEPSK-
T---L

PF05041 // ENSGT00390000013164_1_Domain_0 (1866, 2097)

DSDEDSPLVTLSFALCTLGRRALGTAAHNMAISLDSFLYGLHALFKGDFRITARD
EWVFADMDLLHKVVAPAIR-----MSLKLHQDQFTCPDEYEDPAVLYEAIQSFEK-KVVI
CHEGDPAWRGAVLSNKEELLTLRHVVDEGADEYKVIMLHRSFLNFKVIKVNKECVRGLWA
GQQQELIFLRNRNPERGSIQNNKQVLRNLINSSCDQPLGYPMYVSPLTTSYLGTHKQLKN
VWGGPITLDRIRTWFWTKWVRMRKDCNARQ-QSGGNIEDV-DGGGAP---ATGGNNAPSG
GSQESSAEQPRKGGAQHGVSSC--EGTQRTG----RRKGRSQSVQAHSALSQRPPMLSSS
GPILESRQTFLQTSTSVHELAQRLSESRLSLHTSATSLHSQPPPVTTTGH-LSVRERAEA
LIRSSLGSSTSSTLSFLFGKRSFSSALVISGLSAAEGGNTSDTQSSSSVNIVMGPSARAA
SQATRHLSE-PCEPTDAT-EQGQLRDRRSAEAVAE-TLGVVCRR-ASQEDMGLDDTASQQ
SVSDEQ

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------QARGLSVDSGTDLASSHESAEVTSD-TER
ALPTSKSDLEAKEGQPPSESNFLEFVSLLESISSSKGAVGVPSGLPVGVPTD--------
------------------IPTGVPNGAV-------------------------TEPPQES
RLRERSVDRSALPRVGEEHSSAHFC-LS-P-------VRVRGN------------PVLLS
EGRDSEGGTPEAAGP---------------------QQRP-GLQRAVSGLGAFGL--SDL
LSQ----------SKGPISGPCQDPEDYSCSSSQRKFSREQFYKLIIFPGKWIKVWHDRL
TLLALLDRFRRTEDVKENVLATVLVLLVSLLGFVTLSRGFCKDLWALQFCLVMASCQYSL
LK-----------SVQPDPASPVHGYNQIITYSRPAYFCVLCALILLLDAGSTSRPPPSV
VVFGVRLFSPGGLHLARDALIVFLYCFPAISLLGLFPQIDTFCTYLLEQVDMLVFGGSGI
GDPEALLPCTASPRSLLTAVGLNAFCFSAVKRSPWNPQHVPALFSTFCG-LLVALSYHLS
RHSSDPTVL-LSLFQGKSCPRLLCPAW---AESPSDPLPEKMR--------ESVKEILKS
DLIMCAAMMVLAFAVSASTVFLALRVR--------GCSPGVLALSILPPSCPKHHPWMWL
AHPLLRSHEHRQRHVSEPARLMWFERLYVWLQYLEKLVLYPAVALHGLTVDAFAMSVRRV
PATRCEVFLLTV--AGMKLLRTAFCNPV--HQFLALGFTVLFFRFDCRGASESFLLNFLV
VSILFGK--LDDLLHKLRFVLAYVAPWQIAWGSSFHVFAQLFAIPHSA--------VLFL
QTLGTAALSAPLSPFLGSVIFLASYVRPVRFWEKDYRTR---HLDNSTTRLATQIEKDPG
ADQDNNRNSVFYEHLTRSLQESLCGDLALGRWGSFSAGDCFILASDYLNAFVHLVETGNG
LVTFQLRGLEFR-GTYCQQREVEAITEGDEADQGCCCCRPGHLPHLLSCNAAFSLRWLSW
EVARTQYVLRGYSVSDSSAATMLQVFDLRRILVRFYVQSMIYFVVSSPKLALWIHDESLL
KPLQPYAKWHHIERDPALFSLHVDDDFVPCLQGITRASFCTAYLQWIQFCAQKRQEQR--
----L

PF05041 // ENSGT00390000013164_1_Domain_0 (1866, 2098)

DSDEDSPLVTLCFALCIMGRRTLGVAAHNMAVSLDSFLFGLHTLFKGDFRVAVRD
EWVFADMDLLHRVVAPAVR-----MSLKLHQDQFACPDEYEDPAVLFEAMGAFES-TVVV
CHEGDPGWRRAVLAGREELLTLRRVVDEGADDYKVIRLRRAYLTFKVIKVNRECVRGLWA
GQQQELIFLRNRNPERGSIQNHRQVLRNLINSSCDQPLGYPVYVSPLITSFLGSHDQLGR
VWGGPAGLSRLGAWLRVRWRRMQKDCHAG-HRGSGHIEEGDGSRGGG---ARGTS-----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------

------------------------------------------------------------
-------------------------MASQVLQLLR-------QGVWAALTGGWYHDPEHS
KFTNSC--H-------LYLWLFLL-------LLP--------LALHLAFPPNVL----TA
LFYSGSVTIFFAVIKLISYRLHLMFDKGEAIQHRSPRKRSKRKPEGEPS--SQHTARHKN
PS--NNRQIHSTKKEEPRGSLTTPPLCCSSRGQSVHSQHFSG-PLELPAQETVEDLKGVV
LSEDQPEAL-VSSTSPGIKSESQPASQGRTPEPTPRPACPLKPVTTELFTARKGKESGG-
TAQ-RPARHRSESG-LVNPGALKKLPQLSLSQYDLLETDISFQPWGSEHSVLL-PQ-PTC
TQGPTRAQPQNRSPQDSLSSS-CCQCNTVLAKPT-E-EELT-------------------
---RTSGQMELPLNQEVVDSDGEVAVTLIDTSQPGEPLSLHEPIKIVITMSSTQNS-ISD
LESSLHLRVTSSDRTSVRPSAESAGSGGAGPADP-EQVRIPLITLELTEDGR-GRGISCS
EGNGGERTPERME-VM-SPDRCS----GSGPGD-----GSPT----PGSTLATLTPRVDP
E-------SEGSREGQANLDPASCKSSHEKRHARVLSVDSGTDVFLSRSTKEVVSD-GEK
PIPTSKSDLEAKEGQIPNESNFLEFVSLLESISTSKVVVPDS---PAEQKEASQGPE---
-------GHASPGTKEEAVENEKPNGRD-----PKPGKPDLPSQDPANGSPVFTQPAKSA
ALFQGSRQRHIIYRVTSQQDSSVLQVISGPETSVQEEMSLDAMHVFIDEH-GEVRSCYLK
SGNQKEGSSQHPPLNPDCVSHAREILLSSSSTTTTGSPDPSSGDLAVSALQQQLLLMVAR
RTQSETPRH-----------VSQDLEDSSHSSAQGKFNREQFYKFIVFPGKWIKVWYDRL
TLLALLD---RTEDVKENMVAVLLSVLVSLLGFLTLNRGFCRDLWVLLFCLVMASCQYSL
LK-----------SVQPDPASPIHGHNQIIAYSRPIYFCMLCGLILLLDAGAKAKQPPSY
VVYGLKLFTPETLQAVRDHLIVFLCCFPAISLLGLFPQINTFCTYLLEQIDMLLFGGSAV
SGITSAV--YSVGRSVLAAALLHAFCFSAVK-EPWSTQHIPALFSAFCG-LLVALSYHLS
RQSSDPSVL-LSFIQCKLLPKCLHQNL---EESATDPLPQRMK--------DSVKDVLRS
DLVICSAAAVLSFAVSASTVFLSLRPFLSIVLFALAGTVGLIT-HHLLPQLRKHHPWMWI
SHPVLRSKEYQQREARDIAHLMWFERLYVWLQCFEKYLLYPAIVLNALTLDAFSISNYRR
LGTHWDIFLMIT--AGMKLLRTSFCNPV--HQFANLGFTVIFFHFDCKDISESFLLDFFM
VSIVFTK--LGDLLQKLQFVLAYVAPWQMAWGSSFHVFAQLFAIPH--------SAMLFF
QTFATSIFSTPLSPFLGSVIFITSYVRPVKFWERSYNTR---RMDNSNTRLAVQMERDPG
SD-DNNLNSIFYEHLTRTLQESLCGDLVLGRWGNYSSGDCFILASDDLNAFVHLIEIGNG
LVTFQLRGLEFR-GTYCQQREVEAIMEGDEDDRGCCCCKPGHLPHLLSCNAAFHLRWLTW
EITRTQYILEGYSIIDNNAATMLQVYDLRRVLIRYYVKSIIYYMVTSPKLVSWVKNESLL
KSLQPFAKWHHIERDLAMFNINIDDDYVPCLQGITRASYCNVFLEWIQYCAGKRQELSK-
TLEHV

PF05041 // ENSGT00390000013164_1_Domain_0 (1866, 2097)

DSDEDSALVTLAFALCILGRRALGTAAHNMAMSLDSFLYGLHALFKGDFRVTARD
EWVFADMDLLHKVVVPAIR-----MSLKLHQDQFTCPDEYEDPAVLYEAIRSFEK-KVVI
CHEGDPAWRGAVLSNKEELLTLRHVVDEGADEYKVIMLHRGFLSFKVIKVNKECVRGLWA
GQQQELIFLRNRNPERGSIQNNKQVLRNLINSSCDQPLGYPMYVSPLTTSYLGTHKQLQS
VWGGPVTLNRVRTWFQTRWLRMRKDCSVGHRSGGGNIEDG-EGGAVP---SAGGGSAPNG
ESRDGSTEQPRKGGTQQWASPR--GEAQRAG----RRKGRSQSVQAHSAISQRPPTLSSS
GPILESHQAFLQTSTSVHELAQRPSGSRLSLHTSAASLHSQPPPVTTTGH-LSVRERAEA
LIRSSLGSSTSSTLSFLFGKRSFSSALVISGLSAAEGGNTSDTQSSSSVNIVMGPSARAA
GHAARHFSE-PCEPTDSP-EQGQLQDGRLAEAMEE-NLGVLCRR-ASQEDMGLDDTASQQ
STSDEQ

------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------AFPPNVI----TA
LFYCSSVTVLFTVIKVVSYRLHLMFDKGEVIQQRSPRQVEKPKKDREAN--SEHATNPKI
PS--STRPIHSSKKEEIGRSVPTPPLHCSSRGQSLSSHRSSG-PLELPAQETVEDLKGVV
LSEDHPGAP-VSSTSPGIRTESLPASQVCLPEPMHRSAEPTKPAVPETLISGKRRGQEG-
QGQ-HPPRHRSEGG-LVDKGDLKKLQRLSLSQYDLLETDVSFQPWGSENSVLI-PEPLTC
HQDSISKQLQSKSPQDSLSNS-CPQCHTVMAKPT-QRLVG--------------------
----TSSHVALPFSQGVNSSDSEVAVTLIDTSQPGDPLSLHEPIKIVITMSSTSNS-TTE
VGSSLHLKVTGTEQVSPGAHIEPASPRK-HPTNA-EHIQIPVITLELSEDGG--GSVTVP
EGQRNRRTSDQLNVG--DSDQCSS-----GE--------------HDWEPAQTPTSAVAS
E-------AEGETDGQASLDPVSCRGSHEKRHARVLSVDSGTDVFLSRSSTEVVSD-KEK
TIPTSKSDLEAKEGQIPNESNFLEFVSLLESINTSKVVASTQPKDPADQHGAGE------
-FG--------SAIPEEIPEKEKPSGQH-----SKPEKPELQSQDHPGTSPVFSPPARTT
ALFQGNRQRQIIYRVTSQQDSSVLQVISGPETSVQEEMSVDAMHVFMDEH-GELESALLI
SKMGK-------------VELPGEVHLSSSSTTTCESPDPSSGDPAVSALQQQLLLMVAR
RTHSETPR-----------HVSQDLEDSSCSSAAGKFNREQFYKFIIFPGKWIKVWYDRL
TLLALLD---RTEDVKENVLAIVLSILVSLLGFLTLNRGFCRDLWVLLFCVVMASCQYSL
YN-----------S--------DAGHNQIITYSRPIYFCVLCGLILLLDAEAKSRHPPRY
VVYGLKLFSPESLQT-----------------------INTFCTYLLEQIDMLLFGGSAV
SGIVSAV--YSVGRSILAAALLHVFCFSAVK-EPWSTQHIPALFSAFCG-LLVALSYHLS
RQSIALCL---S----------LFHAV---AASATDPLPQKMK--------DSVKDVLRS
DLVVCSVAAVLSFAVSASTVFLSLRPFLSVVLFALAGTVGFIT-HHLLPQLRKHHPWMWV
SHPVLKSREYQQREVGDIAHLMWFERLYVWLQCFEKYILYPAIILNALTIDAFSISNYRR
LGTHWDIFLMII--AGMKLLRTSFCNPV--HQFTHLSFTLIFFHFDYKDFSESFLLDFFM
VSILLSK--LEDLLHKLQFVLAYVAPWQMAWGSSFHVFAQLFAIPHIL--------STSQ
ELTMTF-----------------------YSFVAPSSTK---RVDNSNTRLAVQIERDAG
GD-DNNLNSIFYEHLTRTLQESLCGDLVLGRWGNYSSGDCFILASDDLNAFVHLIEIGNG
LVTFQLRGLEFR-GTYCQQREVEAIMESDEDDRGCCCCQPGHLPHLLSCNAAFHLRWLTW
EVTRTQYILEGYSIIDNNAATMLQVFDLRRVLIRYYIKSIIYYMVTSPKLLSWVKNESLL
KSLQPFAKWHHIERDLAMFNINIDDDYVPCLQGITRASYCNVYLEWIQYCAGKRQEVGA-
K---EVAGAATLSASVKAKDCQP--------------SSSSCTPGLV-------------
------------LVTICTF-----AHV

PF05041 // ENSGT00390000013164_1_Domain_0 (1948, 2097)

DFPQDQFTCPDEYEDPAVLYGAIQSFEQ-KVVI
CHEADPAWRSAVLSNKEELLTLRHVVDEGTDEYKVIMLHRGFLSFKVIKVNKECVRGLWA
GQQQELIFLRNRNPERGSIQNNKQVLRNLVNSSCDQPLGYPMYVSPLTTSYLGTHQQLRN
VWGGPVTLNSLRTWFQARWLSMRKDCNTG-QSSRGAIEDLDGGGAPNG------------
---DGSVEQPHKGGTQHWVSPRE--GAQRTG-----RKGRSQSVQAPSVLSQRLPNLSSS
GPIVESRQAFLQTSTSVHELAPRPLGSRLSLHTSATSLHSQPPPVTTTGH-LSVRERAEA
LIRSSLGSSTSSTLSFLFGKRSFSSALVISGLSAAEGGNTSDTQSSSSVNIVMGPSARAA
GHATRHFSE-PCDPTEAA-EQRQLRDRRLAEAVAE-NLGVMCRR-ASQEDMGLDDTASQQ
SASDEQ

------------------------------------------------------------
-------------------------MVSQVLQLLR-------QGVWAALTGGWYHDPEQS
KFTNSC--H-------LYLWLFLL-------LLP--------LALHLAFPPNAI----IV
FFYCSAVTIFFTIIKLVSYRLHLMFDKGEVIQQKPSGKEEKPNKDKEAK--GEHITNHKN
PS--NNRQIHNGKKDEASRNLSTPPLRCSSRGQSITSHHSSG-PLELSAQETVEDLKGVI
LSEDHPIAP-VSSTSPGIKMESLPACQAHALETMPKSAIPVKPVATETLINGKRKERGG-
KGQ-PPLRHRSEGG-LVDKGPLKKLPHLSLSQYDLLETDVSFQPWGSENSVLI-PEPVNC
PQGSIRERVQSRSPQDSLSSS-CPQCDTIVAKPV-EEPADTSCQVD--------------
----TSCQVDLPLNQEVDSSDSEVAVTLIDTSQPGDPLSLHEPIKIVITMSSTPNS-MTD
LESSLHLKVVGIEKTGVKSDAEPTNPGAASSLNA-AQISIPVITLDLPEGGG--GGVPCP
EGNGSERTPERLK-ARVSTNQCSG--YGSGEGGSATKDHSSSS-REPWESASRLTPDTAS
E-------SKVGKEGLTNLDPLSCKSSHEKRHARVLSVDSGTDVFLSKSSAEIIND-TEK
TMPTSKSDLEAKEGQIPNESNFLEFVSLLESINTSKMAASNQLNGSAEQNEESGLLR---
-------DNTCQGKKEEILENEKPSGHS-----SKQGKPDLQSQDHTSTSPACTQPAKTT
AFFQGNRQRQIIYRVTSQQDSSVLQVISGPETSVQEEISVDAMHVFIDEH-GESLELFTN
EQAGKTVTL---------DLRTGRLNVSSSSTTTSESQDPSSGDPAVSALQQQLLLMVAR
RTQSETPRH-----------VSQDLEASSCSSTQGKFNREQFYKFIIFPGKWIKVWYDRL
TLLALLD---RTEDIKENVLAILLIVLVSLLGFLTLSRGFCKDMWVLLFCLVMASCQYSL
LK-----------SVQPDPASPIHGHNQIITYSRPIYFCVLCGLILLLDTGAKARHPPSY
IVYGLKLFSPVFLQSARDYLIVFLYCFPAISLLGLFPQINTFCIYLLEQIDMLFFGGSAV
SGITSAV--YSVARSILAAALLHAVCFSAVK-EPWSTQHIPALFSAFCG-LLVALSYHLS
RQSSDPSVL-MSFIQCRLLPKFLHQNL---EESAADPLPKKMK--------DSVTDVLKW
DLIVCAVVAVLSFAVSTSTVFLSLRPFLSIVLFALAGAVGFVT-HYLLPQLRKHHPWMWI
SHPILKNKEYHQREVRDVAHLMWFERLYVWLQCFEKYILYPALILNALTIDAFLISNHRR
LGTHWDIFLMII--AGMKLLRTSFCNPV--YQFINLSFTVIFFHFDYKDISESFLLDFFM
VSILFSK--LGDLLHKLQFVLTYVAPWQMAWGSSFHVFAQLFAIPH--------SAVLFF
QTIATSIFSTPLSPFLGSVIFITSYVRPVKFWEKNYNTR---RVDNSNTRLAVQIERDPG
ND-DNNLNSIFYEHLTRTLQESLCGDLVLGRWGNYSSGDCFILASDDLNAFVHLIEIGNG
LVTFQLRGLEFR-GTYCQQREVEAIMEGDEEDRGCCCCKPGHLPHLLSCNAAFHLRWLTW
EITRTQYILEGYSILDNNAATMLQVFDLRRILIRYYIKSIIYYMVTSPKLLSWIKNESLL
KSLQPFAKWHYIERDLAMFNINIDDDYVPCLQGITRASFCNVYLEWIQHCARKTQEPSK-
T---LDSDEDSPLVTLSFALCTLGRRALGTAAHNMAMSPTLD--SGHSL-CGHLGLSLMI
AAGLAD-------DSSVAH-----THTYS

PF05041 // ENSGT00390000013164_1_Domain_0 (1950, 2097)

HKDQFTCPDEYEDPAVLYE------K-KVVI
CHEGDPAWRGAVLSNKEELLTLRHVVDEGADEYKVIMLHRSFLSFKVIKVKKECVRGLWA
GQQQELIFLRNRNPERGSIQNNKQVLRNLINSSCDQPLGYPMYVSPLTTSYLGTHKQLKN
VWGGPITLDRIRTWFWTKWVRMRKDCNARQ-QSGGNIEDM-DGGGAP---TTGGNNAPSG
GSQESSAEQPRKGGAQHGVSSC--EGTQRTG----RRKGRSQSVQAHSALSQRPPMLSSS
GPILDSRPTFLQTSTSVHELAQRLSESRLSLHTSATSLHSQPPPVTTTGH-LSVRERAEA
LIRSSLSSSTSSTLSFLFGKRSFSSALVISGLSAAEGGNTSDTQSSSSVNIVMGPSARAA
SQATRHLSE-PCEPTDAT-EQGQLRDRRLAE-----TLGVVCRR-ASQEDMGLDDTASQQ
SVSDEQ

------------------------------------------------------------
-------------------------MASQVLQLLR-------QGVWAALTGGWYHDPEHS
KFTNSC--H-------LYLWLFLL-------LLP--------LALHLAFPPNLL----TA
LFYCGSVTIFFTVIKLISYRLHLMFDKGEVIQHRSPRKRSKRRPEGEAS--SQHPPRHKI
PS--NNRQIHSTKKEESR-SLTTPPLCCSSRGQSVHSQHSSG-PLELPAQETVEDLKGVV
LSEDQPEAL-VSSTSPGMKSESLPASQGRTPEPTPRPPCPVKPVTTEIFPARRVKESGG-
TAQ-RPARHRSESG-LVNTEALKKLPHLSLSQYDLLETDISFQPWGSEHSVLI-PQ-PNC
PHAPTRAQPQSRSPQDSQSSS-FCQCNTVIAKPT-E-EELT-------------------
---RTSGQVELPSNPEVVDSDGEVEVTLIDTSQPGEPLSLHEPIRIVITMSSTPNS-ISD
PESSLHLRVTSSDRTGVRPNAENAGPGGADPADP-EQARIPLITLELTEDGRGGGGPSCP
EGNGGERTPEKME-VM-SPDRRS----SSGVGECSTKDESPT----PGPTFVPLTPRADP
E-------SEGSREGPANLDPASCKSSHEKRHARVLSVDSGTDVFLSRSTKEVVSD-SEK
PIPTSKSDLEAKEGQIPNESNFLEFVSLLESISTSKAVAPDS---AAEQKGVNQGPE---
-------GHASPGIKEEAVENEKSNGRD-----PKPGKPDLPSQDPASASPVLTQPPKTT
ALFQGSRQRHIIYRVTSQQDSSVLQVISGPETSVQEEMSLDAMHIFIDEH-GEVRSCYLK
SGNQKEGSSQHPPLNPDCVSHAREILLSSSSTTTTGSPDPSSGDPAVSALQQQLLLMVAR
RTQSETPRH-----------VSQDLEDSSRSSAQGKFNREQFYKFIIFPGKWIKVWYDRL
TLLALLD---RTEDVKENMVAVLLSVLVSLLGFLTLNRGFCRDLWVLLFCLVMASCQYSL
LK-----------SVQPDPASPIHGHNQIIAYSRPIYFCMLCGLILLLDAGAKARHPPSY
VVYGLKLFTPETLQSVRDHLIVFLCCFPAISLLGLFPQINTFCTYLLEQIDMLLFGGSAV
SGITSAV--YSVGRSVLAAALLHVFCFSAVK-EPWSTQHIPALFSAFCG-LLVALSYHLS
RQSSDPSVL-LSFIQCKLLPKCLHQNL---DESAADPLPQRMK--------DSVKDVLRS
DLIICSAAAVLSFAVSASTVFLSLRPFLSIVLFALAGTVGLIT-HHLLPQLRKHHPWMWI
SHPVLKSKEYQQREARDIAHLMWFERLYVWLQCFEKYLLYPAIVLNAVTLDAFSISNYRR
LGTHWDIFLMIT--AGMKLLRTSFCNPV--HQFANLGFTVVFFHFDYKDVSESFLLDFFM
VSIVFTK--LGDLLQKLQFVLAYVAPWQMAWGSSFHVFAQLFAIPH--------SAMLFF
QTFATSIFSTPLSPFLGSVIFITSYVRPVKFWERSYNTQ---RVDNSNTRLAVQMERDPG
SD-DGSLNSIFYEHLTRTLQDSLCGDLALGRWGNYSSGDCFILASDDLNAFVHLIEIGNG
LVTFQLRGLEFR-GTYCQQREVEAIMEGDEDDRGCCCCKPGHLPHLLSCNAAFHLRWLTW
EITRTQYILEGYSIIDNNAATMLHVFDLRRVLIRYYIKSIIYYMVTSPKLASWVKNESLL
KSLEPFAKWHHIERDLAMFNINIDDDYVPCLQGITRASYCSVFLEWIQYCAGKRQELSK-
TLDHV

PF05041 // ENSGT00390000013164_1_Domain_0 (1866, 2097)

DSDEDSALVTLSFALCILGRRALGTAAHNMAMSLDSFLYGLHALFKGDFRVTARD
EWVFADMDLLHKVVVPAIR-----MSLKLHQDQFTCPDEYEDPEILYEAIQSFEK-KVVI
CHEGDPAWRGAVLSNKEELLTLRHVVDEGANEYKVIMLHRGFLSFKVIKVNKECVRGLWA
GQQQELIFLRNRNPERGSIQNNKQVLRNLINSSCDQPLGYPMYVSPLTTSYLGTHKQLQS
VWGGPITLNRVRTWFQTRWLRMRKDCSVGQRSG-GNIEDG-EGAVP------PGGNAPSG
ESRDSSTEQPRKGGTQQWASPR--GEAPRAG----RRKGRSQSVQAHSAISQRRPTLSSS
GPILESHQAFLQTSTSVHELAQRPSGSRPSLNTSAGSLHSQPPPVLTTGPYLGIQHQAEA
LIQSSLGSSTSSTLSFLFGKRSFSSALVISGLSAAEGGNTSDTQSSSSVNIVMGPSARAA
ARSLKHFSE-PCEPIDSP-EQGQLQDGRLAEAAGENPRGVLCRR-ASQEDMGLDDTASQQ
STSDEQ

------------------------------------------------------------
-------------------------MASQVLQLLR-------QGVWAALTGGWYHDPEHS
KFTNSC--H-------LYLWLFLL-------LLP--------LALHLAFPPNFL----TA
LFYCGSVTIFFAVIKLISYRLHLMFDKGEAIQHRSPRKRSKRKPEGEAS--SQHTARHKN
PS--NNRQIHSTKKEEPRGSLTTPPLCCSSRGQSVHSQHSSG-PLELPAQETVEDLKGVV
LSEDQPEAL-VSSTSPGMKSESLPASQGRTPEPTPRPACPVKPVTTELFTARKGKESGG-
TAQ-RPARHRSESG-LVNTGALKKLPQLSLSQYDLLETDISFQPWGSEHSVLI-PQ-PNC
TQSPTRAQPQSRSPQDSLSSS-CCQCNTVLAKPT-E-EELT-------------------
---RTSGQVELPLNQEVVDSDGEVAVTLIDTSQPGEPLSLQEPIKIVITMSSTQNS-ISD
LESSLHLRVTSSDRTSVRPKVESAGAGGAGPADP-EQVRIPLITLELTEDGG-GRGVSCS
EGNGGERTPERME-VM-PPDRCS----GSGPGECSTKDRSPT----PGPTLVTLTPRVDP
E-------SEGSREGQASLDPASCKSSHEKRHARVLSVDSGTDVFLSRSTKEVVSD-GEK
PIPTSKSDLEAKEGQIPNESNFLEFVSLLESISTSKVVAPDS---AAEQKGANQGPE---
-------GHASPGTKEEAVENEKPSRRD-----PKPGKPDLPSQDPANDSPVFTQPAKST
ALFQGSRQRHIIYRVTSQQDSSVLQVISGPETSVQEEMSLDAMHVFIDEH-GEVRSCYLK
SGNQREGSSQHPPLNPDGVSHAREILLSSSSTTTTGSPDPSSGDPAVSALQQQLLLMVAR
RTQSETPRH-----------VSQDLEDSSRSSAQGKFNREQFYKFIIFPGKWIKVWYDRL
TLLALLD---RTEDVKENMVAVLLSVLVSLLGFLTLNRGFCRDLWVLLFCLVMASCQYSL
LK-----------SVQPDPASPIHGHNQIIAYSRPIYFCMLCSLILLLDAGAKARHPPSY
VVYGLKLFTPETLQAVRDHLIVFLCCFPAISLLGLFPQINTFCTYLLEQIDMLLFGGSAV
SGITSAV--YSVGRSVLAAALLHAFCFSAVK-EPWSTQHIPALFSAFCG-LLVALSYHLS
RQSSDPSVL-LSFIQCKFLPKCLHQNL---EESATDPLPQRMK--------DSVKDVLRS
DLVICSAAAVLSFAVSASTVFLSLRPFLSIVLFALAGTVGLIT-HHLLPQLRKHHPWMWI
SHPVLRSKEYQQREARDIAHLMWFERLYVWLQCFEKYLLYPAIVLNALTLDAFSISNYRR
LGTHWDIFLMIT--AGMKLLRTSFCNPV--HQFANLGFTVIFFHFDYKDISESFLLDFFM
VSIVFTK--LGDLLHKLQFVLAYVAPWQMAWGSSFHVFAQLFAIPH--------SAMLFF
QTFATSIFSTPLSPFLGSVIFITSYVRPVKFWERSYNTR---RMDNSNTRLAVQMERDPG
SD-DNNLNSIFYEHLTRTLQESLCGDLVLGRWGNYSSGDCFILASDDLNAFVHLIEIGNG
LVTFQLRGLEFR-GTYCQQREVEAIMEGDEDDRGCCCCKPGHLPHLLSCNAAFHLRWLTW
EITHTQYILEGYSIIDNNAATMLQVYDLRRVLIRYYVKSIIYYMATSPKLVSWVKNESLL
KSLQPFAKWHHIERDLAMFNINIDDDYVPCLQGITRASYCNVFLEWIQYCAGKRQELSK-
TLEHV

PF05041 // ENSGT00390000013164_1_Domain_0 (1866, 2097)

DSDEDSALVTLSFALCILGRRALGTAAHNMAMSLDSFLYGLHSLFKGDFRVTARD
EWVFADMDLLHKVVVPAIR-----MSLKLHQDQFTCPDEYEDPAVLYEAIRSFEK-KVVI
CHEGDPAWRGAVLSNKEELLTLRHVVDEGADEYKVIMLHRGFLSFKVIKVNKECVRGLWA
GQQQELIFLRNRNPERGSIQNNKQVLRNLINSSCDQPLGYPMYVSPLTTSYLGTHKQLQS
VWGGPVTLTRVRTWFQTRWLRMRKDCSVGQRSGGGNIEDG-EGGALP---SVGGGSAPNG
ESRDGSTEQPRKGGTQQWASPR--GDAQRAG----RRKGRSQSVQAHSAISQRPPTLSSS
GPILESHQTFLQTSTSVHELAQRPSGSRLSLHTSAASLHSQPPPVTTMGH-LSVRERAEA
LIRSSLGSSTSSTLSFLFGKRSFSSALVISGLSAAEGGNTSDTQSSSSVNIVMGPSARAA
GHAARHFSE-PCEPTDSP-EQGQLQDERLAEAVEE-NLGVLCRR-ASQEDMGLDDTASQQ
STSDEQ

------------------------------------------------------------
-------------------------MVSQVLQLLR-------QGVWAALTGGWYHDPEQS
KFTNSC--H-------LYLWLFLL-------LLP--------LALHLAFPPNVI----IV
FFYCSAVTIFFTIIKLVSYRLHLMFDKGEVIQQKPSRKEEKPNKDKEAK--GEHITNPKN
PS--NNRQIHNGKKEEASRNLSTPPLRCSSRGQSITSHHSSG-PLELSAQETVEDLKGVI
LSEDHPIAP-VSSTSPGIKMESLPACQAHMLETMPKSAIPVKPIATETLINGKGKERGG-
KGQ-PPLRHRSEGG-LVDKGPLKKLPHLSLSQYDLLETDISFQPWGSENSVLI-PEPVSC
PQGSVRERVQSKSPQDSLSSS-CPQCDTIVAKPV-EEPADTSCQVD--------------
----TSCQVDLPLNQEVDSSDSEVAITLIDTSQPGDPLSLHEPIKIVITMSSTPNS-MTD
LESSLHLKVVGIEKTGVKSDAEPTNPGAASSPNA-EQISIPVITLDLPEGGG--GGVPCS
EGNGSERTPERLK-ARVSTNQCSG--YGSGEGGSATKDHSSSS-REPWESASRLTPDTAS
E-------SKVGKEGLTNLDPLSCKSSHEKRHARVLSVDSGTDVFLSKSSAEIVND-TEK
TMPTSKSDLEAKEGQIPNESNFLEFVSLLESINTSKMAASNQLNGSAEQNEESGLLQ---
-------DNTSQEKKEEILENEKPSGHS-----PKQGKPDLQSQDHTSTSPVCTQPAKTT
AFFQGNRQRQIIYRVTSQQDSSVLQVISGPETSVQEEISVDAMHVFIDEH-GEIRSCYLK
SGNQKEGPLQPLPSNCDCLSQAREMQVSSSSTTTSESQDPSSGDPAVSALQQQLLLMVAR
RTQSETPRH-----------VSQDLEASSCSSTQGKFNREQFYKFIIFPGKWIKVWYDRL
TLLALLD---RTEDIKENVLAILLIVLVSLLGFLTLSRGFCKDMWVLLFCLVMASCQYSL
LK-----------SVQPDPASPIHGHNQIITYSRPIYFCVLCGLILLLDTGAKARHPPSY
IVYGLKLFSPVFLQSARDYLIVFLYCFPAISLLGLFPQINTFCIYLLEQIDMLFFGGSAV
SGITSAV--YSVARSFLAAALLHAVCFSAVK-EPWSTQHIPALFSAFCG-LLVALSYHLS
RQSSDPSVL-MSFIQCRLLPKFLHQNL---EESAADPLPKKMK--------DSVTDVLKW
DLIVCAVVAVLSFAVSASTVFLSLRPFLSIVLFALAGAVGFVT-HYLLPQLRKHHPWMWI
SHPILKNKEYHQREVRDVAHLMWFERLYVWLQCFEKYILYPALILNALTIDAFLISNHRR
LGTHWDIFSLIDPLLGWATVAGLHFEPV--YRL-LLSFTVIFFPLDYKVFRE-FLLDFL-
------M--LGDLLHKLQFVLTYVAPWQMAWGSSFHVFAQLFAIPH--------SAVLFF
QTIATSIFSTPLSPFLGSVIFITSYVRPVKFWEKNYNTR---RVDNSNTRLAVQIERDPG
ND-DNNLNSIFYEHLTRTLQESLCGDLVLGRWGNYSSGDCFILASDDLNAFVHLIEIGNG
LVTFQLRGLEFR-GTYCQQREVEAIMEGDEDDRGCCCCKPGHLPHLLSCNAAFHLRWLTW
EITRTQYILEGYSILDNNAATMLQVFDLRRILIRYYIKSIIYYMVTSPKLLSWIKNESLL
KSLQPFAKWHYIERDLAMFNINIDDDYVPCLQGITRASFCNVYLEWIQHCARKTQEPSK-
T---L

PF05041 // ENSGT00390000013164_1_Domain_0 (1866, 2097)

DSDEDSPLVTLSFALCTLGRRALGTAAHNMAISLDSFLYGLHALFKGDFRITARD
EWVFADMDLLHKVVAPAIR-----MSLKLHQDQFTCPDEYEDPAVLYEAIQSFEK-KVVI
CHEGDPAWRGAVLSNKEELLTLRHVVDEGADEYKVIMLHRSFLSFKVIKVNKECVRGLWA
GQQQELIFLRNRNPERGSIQNNKQVLRNLINSSCDQPLGYPMYVSPLTTSYLGTHKQLKN
VWGGPITLDRIRTWFWTKWVRMRKDCNARQ-QSGGNIEDV-DGGGAP---ATGGNNAPSG
GSQESSTEQPRKGGAQHGVSSC--EGTQRTG----RRKGRSQSVQAHSALSQRPPMLSSS
GPILESRQTFLQTSTSVHELAQRLSESRLSLHTSATSLHSQPPPVTTTGH-LSVRERAEA
LIRSSLGSSTSSTLSFLFGKRSFSSALVISGLSAAEGGNTSDTQSSSSVNIVMGPSARAA
SQATRHLSE-PCEPTDAT-EQGQLRDRRPAEAVAE-TLGVVCRR-ASQEDMGLDDTASQQ
SVSDEQ

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------MWFERLYVWLQCFEKYVLYPAIILNALTIDAFSISNYRR
LGTHWDIFLMIM--AGMKLLRTSFCNP-V-HQFVNLSFTVIFFHCDYKDISESFLLDFFM
VSIFFSK--LGDLLHKLQFIMTYVAPWQMAWGSSFHVFAQLFAIPHSA--------MLFF
QAIATSIFSTPLSPFLGSVIFITSYVRPVKFWEKNYNTR---RMDNSNTRLAVQIERDPG
NN-DNNLNSIFYEHLTRTLQESLCGDLVLGRWGNYSSGDCFILASDDLNAFVHLIEIGNG
LVTFQLRGLEFR-GTYCQQREVEAIMEGDEDDRGCCCCKPGRLPHLLSCNAAFHLRWLTW
EIMRTQYILEGYSIIDNNAATMLQVFDLRRILIRYYVKSIIYYMVTSPKLLSWIKNESLL
KTLQPYAKWHYIERDLAMFNINIDDDYVPCLQGITRASFCNMYLEWIQYCARKRQ

PF05041 // ENSGT00390000013164_1_Domain_0 (1856, 2098)

EPAK-
T---VS-DEDSPL--LSFALCIG-RRA-LTAAHNMVLSLDSFLYGLHALFKGDFRITARD
EWVFADMDLLHKVVAPAIR-----MSLKLHQDQFTCPDEYEDSVVLYEAIQSFEK-KVVI
CHEGDPAWRGAVLSNQEELLTLRHVVDEGSDEYKVIMLHRSFLSFKVIKVNKECVRGLWA
GQQQELIFLRNRNPERGSIQNNKQVLRNLINSSCDQPLGYPMYVSPLTTSYLGTHRQLKD
VWGGPITLDRIRTWFRTKWLRVRKDCNTG-QHNRANIEDVDGGGAP----SVGGSMALSA
DSQASSAEQPRKRGSQHWASPR--EGTRRAG----RRKGRSQSVQAHSALSQRPPTLSSS
GPILESCQVFLPASSSVHELAQRLSGSRLSLHNSAASLHSQPPPVTTTGH-LSVRERAEA
LIRSSLGSSTSSTLSFLFGKRSFSSALVISGLSAAEGGNTSDTQSSSSVNIVMGPSARAA
SQATRHYSE-PCEPTDSM-EQEQYCDQRLVEAMAD-SRGMTCRR-ASQEDMGLDDTASQQ
SASDEQ

------------------------------------------------------------
-------------------------MVSQALQLLR-------QGVWAALTGGWYHDPEQS
KFTNSC--H-------LYLWLFLL-------LLP--------LALHLAFPPNAI----TV
FFYCSSVTIFFTIIKLVSYRLHLMFDKGEVIQQRPSKKKEKPSKDKEAN--KEHMTNHKN
QS--STRQINNGKKEEPHRNLSTPPLRCSSRGQSINSQHSSG-PLELPAQETVEDLKGVI
LSEDQPVAP-VLSTSPGVRTG----SKVCAPETTTTPAIPRKPAVAGSPASDEGKERGG-
RRQ-PPLRHRSEGG-LVEKEASKKLPHLSLSQYDLLETDVSFQPWGSENSVLS-PEPANY
ASGSLRDRWQRESPPDSLSSS-CPQCNTVIARPA-RASPG--------------------
----ASRQADPPLKQEVDYSDSEVAVTLIDTSQPGDPLSLHEPIKIVITMSSTPNS-MTD
LESSLHLKVIGTERAGFTSDAEPAAPGVASPPNT-EQIRIPVITLELSEDGA--GGAVCP
EGSGGDRSPERLM-VEASSNQCSG--YESGEGGNATKDGSPSPTGDCCEATPPFTPHAAP
E-------TEGGKEGQANLDPSSCKTSHEKRHARVLSVDSGTDVFLSKSSAEIISD-KEK
TIPTSKSDLEAKEGQIPNESNFLEFVSLLESINTSKLAASNQRNSSVEQNKDSGLLG---
-------DTCSQEKREEIQEREKPNGHS-----SKQGKPDVQSQDHTSTSPVFTEPAKIT
TLFQGNRQRQIIYRVTSQQDSSVLQVISGPETSVQDEMSVDAMHVFIDEH-GEIRSCYLK
SGNQKEGPLQHQPSNYDSFSRARDIQISSSSTTTSESQDPSSGDPAVSALQQQLLLMVAR
RTQSETPR-----------HLSQDLEDSSCSSTQGKFNREQFYKFIIFPGKWIKVWYDRL
TLLALLD---RTEDVKENVLAVLLIVLVSLLGFLTLNQGFCKDMWVLLFCLVMASCQYSL
LK-----------SVQPDPASPIHGHNQIITYSRPIYFCVLCGLILLLDTGAKARHPPTY
VVYGLKLFSPRSLQSARDLLIVFLYCFPAISLLGLFPQIDTFCVYLLEQIDMLFFGGSAV
SGMTSAV--YSVARSAASAALLHVLCFSAVK-EPWSTQHIPALFSAFCG-LLVALSYHLS
RQSSDPSVL-LSFIHCRLLPKFLHQNL---EELAADPLPKKMK--------GSVKDILKS
DLIICSVAAVLSFAISASTVFLSLRPFLSVVLFALAGSVGFVT-HYMLPQLRKHHPWMWI
SHPVLKNKEYQQREVRDIAHLMWFERLYVWLQCFEKYILYPAIILNALTIDAFSISNYRR
LGTHWDIFLMIV--AGMKLLRTSFCNP-A-HQFIHVSFTAIFFHFDYKDLSESFLLDFFM
VSIVFSK--LEDLLHKLQFVMTYVAPWQMAWGSSFHVFAQLFAVPRIL--------SA--
-----SIFT--RDPALGSVATAQSL----------SLIP---RSDRSKYPLIIFLVLPLG
ND-DNNLNSIFYEHLTRALQESLCGDLVLGRWGNYSSGDCFILASDYLNAFVHLIEIGNG
LVTFQLRGLEFR-GTYCQQREVEAIMEGDEDDRGCCCCKPGHLPHLLSCNAAFNLRWLTW
EITRTQYILEGYSIIDNNAATMLQVFDLRRILIRYYIKSIIYYMVTSPKLLLWIKNESLL
KSLQPFAKWHYIERDLAMFNINTDDDYVPCLQGITRASYCNVYLEWIQYCARKRQEPSK-
N---L

PF05041 // ENSGT00390000013164_1_Domain_0 (1866, 2097)

DSDEDSPLVTLSFALCILGRRALGTAAHNMALSLDSFLYGLHTLFKGDFRITARD
EWVFADMDLLHKVVAPAIR-----MSLKLHQDQFTCPDEYEDPGVLYEAIQSFEK-KVVI
CHEGDPAWRGAVLSNKEELLTLRHVVDEGTDEYKVIMLHRTFLSFKVIKVNKECVRGLWA
GQQQELIFLRNRNPERGSIQNNKQVLRNLINSSCDQPLGYPMYVSPLTTSYLGTHRQLQS
VWSGPVTLDGIRTWFRTKWLRMRKGCNAG-QHGTGNIEDVDGRAAP----SAGGGRAPGG
ESQESSTEQPRKDGTHHWSPHE---GTQRTG----GRKGRSQSVQAHEALSQRPPGLSSS
GPILESHPAFLQTSTSVHELAQRLSGSRLSLHTSAASLHSQPPPVTTTGH-LSVRERAEA
LIRSSLGSSTSSTLSFLFGKRSFSSALVISGLSAAEGGNTSDTQSSSSVNIVMGPSARAA
SQATRHLSE-PCEPTEAT-EQGQLRDRRLAEAMAE-NGGLMCRR-ASQEDMGLDDTASQQ
SASDEQ

------------------------------------------------------------
-------------------------MASQVLQLLR-------QGVWAALTGGWYHDPEHS
KFTNSC--H-------LYLWLFLL-------LLP--------LALHLAFPPNVL----TA
LFYCGSVTIFFAVIKLISYRLHLMFDKGEVIQPRSPRKKNKRRPEGEAS--SQHTASHKN
PR--NNRQIHSAKKEEPRGSLPTPPLRCSSRGQSVHSQH-SS-PLELPAQETVEDLKGVV
LSEDQPEAV-VSSTSLGIKSESLPASQGRTPEPTPKPAGPVKPVTPEILTGRKGKEPGG-
AGR-RPARHRSESG-LVSTGALKKLPHLSLSQYDLLETDISFQPWGSEHSALI-PQSTKG
PQGPTRTPSQSRSPQDSLSSS-CCQCDTVLAKPT-EEEELT-------------------
---RTSGPVELPLNQEVVDSEGEVAVTLIDNSQPGEPLSLHEPIKIVITMSSTPNS-MSD
LESSLHLRVTSSDGTSVRPDAEPSGPGMAGPADP-EQVRIPLITLELTEDGG-GRGISCP
ERNGGERTPARME-MM-SSDPCP----GCGSGDGECTW--E-----PGPTPAPLTPRVDS
E-------SEGSREGQANLDPASCKSSHEQRHARVLSVDSGTDAFLSRGTKEVAGD-NEK
AIPTSKSDLEAKEGQIPNESNFLEFVSLLESINTSKVVAPDS---AAEP----KGPE---
-------DRASPGTKEEAVESDKPSGHD-----PKPGKPDLPSQDHAVASPVSTHPAT-L
KLSCGSRQRQIIYRVTSQQDSSVLQVISGPETSVQEEISLDAMHVFIDEH-GEIRSCYLK
SGNQKEGSSQHRSSNPDCASRAREILLSSSSTATSGSPDPSSGDPAVSALQQQLLLMVAR
RTQSETPRH-----------VSQDLEDSSRSSAQGKFNREQFYKFIIFPGKWIKVWYDRL
TLLALLD---RTEDVKENVVAILLSVLVSLLGFLTLNRGFCRDLWVLLFCLVMASCQYSL
LK-----------SVQPDPASPIHGHNQIIAYSRPIYFCVLCGLILLLDAGAKARHPHSY
VVYGLKLFSPETLQSVRDHLIVFLCCFPAISLLGLFPQINTFCTYLLEQVDMLFFGGSAV
SGITSAV--YSVGRSVLVAALLHAFCFSAVK-EPWSTQHIPALFSAFCG-LLVALSYHLS
RQSSDPSVL-LSFIQCRLLPTCLHQNL---EESATDPLPQRMK--------DSVKDVLRS
DLVVCSAAAVLSFAVSASTVFLSLRPFLSIVLFALAGTVGLIT-HHLLPQLRKHHPWMWV
SHPVLKSKECQQREARDVAHLMWFERLYVWLQCFEKYLLYPAIVLNALTLDAFSISNYRR
LGTHWDIFLMIT--AGMKLLRTSFCNPV--HQFANLGFTVIFFHFDYKDISESFLLDFFM
VSIVFTK--LGDLLHKLQFVLAYVAPWQMAWGSSFHVFAQLFAIPH--------SAMLFF
QAFATSIFSTPLSPFLGSVIFITSYVRPVKFWERSYNTR---RVDNSNTRLAVQMERDPG
SD-DNNLNSIFYEHLTRTLQESLCGDLVLGRWGNYSSGDCFILASDDLNAFVHLIEIGNG
LVTFQLRGLEFR-GTYCQQREVEAIMEGDEDDRGCCCCKPGHLPHLLSCNAAFHLRWLTW
EITRTQYILEGYRIIDNNAATMLQVFDLRRVLVRYYVKSIIYYMVTSPKLLSWVKNEPLL
KSLQPFAKWHHIERDLAMFNINIDDDYVPCLQGITRASYCTVFLEWIQFCAGKRQELSK-
ALEPV

PF05041 // ENSGT00390000013164_1_Domain_0 (1866, 2097)

DSDEDSPLVTLSFALCILGRRALGTAAHNMAMSLDSFLYGLHALFKGDFRVTARD
EWVFADMDLLHKVVVPAIR-----MSLKLHQDQFTCPDEYEDPAVLYEAIQSFEK-KVVI
CHEGDPAWRGAVLSNKEELLTLRHVVDEGADEYKVIMLHRGFLSFKVIKVNKECVRGLWA
GQQQELIFLRNRNPERGSIQNNKQVLRNLINSSCDQPLGYPMYVSPLTTSYLGTHKQLQS
VWGGPVTLNRMRTWFQTRWLRMRKDCSVGQRTG-GNIEDV-DGGPVP---SAGDSNAPNG
ESRDSSTEQPRKGGTQQWASPR--GGAHRAG----RRKGRSQSVQAHSAISQRPPTLSSS
GPILESHQAFLQTSTSVHELAQRPSGSRLSLHTSAASLHSQPPPVTTTGH-LSVRERAEA
LIRSSLGSSTSSTLSFLFGKRSFSSALVISGLSAAEGGNTSDTQSSSSVNIVMGPSARAA
GRATRHFSE-PCEPTDTP-EQGQLQDRRLAEAVAE-NLGVLCRR-ASQEDMGLDDTASQQ
SASDEQ

------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------ACPANSI----TA
FAYCSLVTVFFTAIKVISYRLHLMFDKGEAIQQQVPRKNGRQRKDAEVP--KENTVLQPS
NH--SNNIGDNGVIGETNQNGSTPTIHDSLRLEALHSQSSSG-AMDLPTRETIEDLKGIT
VLEEQSVPP-ISSTSPGIKGDILPVSSASASGS-TTSAIVTKPAALETLSGTGINQSGE-
NE-----QHGSQV-ILMDKDVAKNFSNISSSQGDIVRTGVSLEPWDSENSV-I-SDHLSN
PRNQRREKLPDGSLQAGFTSN-CPQCSAFATKDP-EL-VE--------------------
----SSCSADS-TNEDLDCSDSETAVAIVDNSLPGDQ--LCEPIKIVITMSSTPNSTLSD
LAGSVHLRALGTERTSSALESGIVTADWQS-QQTNEQLRIPVITFDLSDDS---KGNDCP
EISESERTPEMLR-TDLSSNHCSG--YESGDAVKEHSN----PVNAPTETNTCSDPNQKN
ASENVQNMGLSSKEELQSLDPQSCRTAHEKRHMRVLSVDSGTDVLLSKNSVE-ASD-KEK
TLPTSKSDLEAKEGQVPNESNFLEFVSLLESINTSKMKASNQSTVKMEVTKENVPAG---
-------DSQTTERKEEVMGTEKHREQL-----PKQERSDVQSQDRASTSPVLPESAKFT
ALYQGNRQRQIIYRVTSQQDSSVLQVISGPEASVQDELSVDAMHVFIDENEGEIRSCYLK
ARNFIEGTLSFINKNRDCLLLFIEIQFSSSSTTTSESQEPSSGDQAASALQQQLLLMVAR
RTLSETPR-----------QPSQEPEDSSCSSAQRKLNR-QFYRFIIFPGKWIKVWYDRL
TLLALLD---RTEDIKENVLSILLVVLVSLLGFLTLNQGFCKDIWVLLFCLVMASCQYSL
LK-----------SVQPDPASPVHGHNKIITYSRPVYFCILCGLILLLDAGSKDTNPSVY
TMYGLKLFSPRFLQSARDHIIVFLYCFPAISLLGLFPQINTFCIYLLEQIDILLFGGSAA
SGLVSAL--YSVSRSFVVLTVLYAFCFSAVK-EPWDAQHIPALFSAFCG-LLVALSYHLS
RQSSDPSVL-MSLIQCKYVPHFLRQQF---EDSSADPLPEKMR--------ESVKEILKS
DLIVCTAAAVLSFAVSASTVFLSLRPFLSIVLFALAWTVGFVT-HYILPQLRKHHPWLWI
SHPILKSKEHQQREVRDAAHLMWFERLYVWLQCFEKYVLYPAIILNALTIDAFSISKYKK
LGTHCDIILITV--AGMKLLRSSFCNPI--NQFVTLSFTVIFFHFDYRDISENFLLDFFM
MSIVFHK--LWDLLQKLQFIMTYIAPWQIAWGSSFHVFAQLFAIPH-------NSAMLFF
QTLATSVFSTPLSPFLGSVIFIASYARPIKFWEKNYNTK---RSDHSNTRLAIQIEKDAG
ND-DNNLNSIFYEHLTRSLQESLCGDLILGRWGNYNTGDCFILASDYLNAFVHLIEIGNG
LVTFQLRGLEFR-GTYCQQREVEAITEGDEDDEGCCCCKPGHLPHLLSCNAAFNLRWLTW
EITRTQYILEGYSIIDNNAATMLQVFDLRRILIRYYIKSIIYFTASSPKILEWIKDESIQ
KMLQPYAKWHYIERDLAMFNINIDEDYVPCLQGITRASFCSVYLDWIQYCARKRA

PF05041 // ENSGT00390000013164_1_Domain_0 (1856, 2098)

EL---
-VNHLDSDEDSPLVTLSFALCILGRRALGTASHNMAISLDSFLYGLHALFKGDFRIAAKD
EWVFADMDLLHKVVAPAIR-----MSLKLHQDQFTCPDEYEDPAVLYEAIQSFEE-KVVI
CHEGDPAWRSAVLSNREELLTLRHVVDEGADEYKVIMLHKSYLSFKVIKVNKECVRGLWA
GQQQELIFLRNRNPERGSIQNNKQVLRNLINSSCDQPLGYPMYVSPLTTSYLGTHSQLRN
IWGGPVSLDNIKKWFRSKWLRMRKDCHAA-HHDRGNVEEADTGGA--SGS------NSTG
NSSQSSSSQHTRDGTPQLQPS-SQEAHQRAG----RRKHRSQSVQAHAALNQRPPVSSHS
GPIAESRQPFMQTSTSAHEIAQRLSSSQLSLHNSATSVFSQSPAVPAAGQ-LTVQDRAAA
MLRSSLASSTSSTLSLLFGKRSFSSALVISGLSAADGGNTSDTQSSSSMNIAMGPSARAA
SQTTRQLTE-TCDATDAT-ESKPRREQGLSHAILM-SQTLECRR-ASQEDMALEDTASQQ
SLSDEQ

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------MTLMQLP----LL---SLSSLMN
CFFFYFQ--LGDLLHKLQFVLTYVAPWQMAWGSSFHVFAQLFAIPH--------SAVLFF
QTIATSIFSTPLSPFLGSVIFITSYVRPVKFWEKNYNTR---RVDNSNTRLAVQIERDPG
ND-DNNLNSIFYEHLTRTLQESLCGDLVLGRWGNYSSGDCFILASDDLNAFVHLIEIGNG
LVTFQLRGLEFR-GTYCQQREVEAIMEGDEEDRGCCCCKPGHLPHLLSCNAAFHLRWLTW
EITRTQYILEGYSILDNNAATMLQVFDLRRILIRYYIKSIIYYMVTSPKLLSWIKNESLL
KSLQPFAKWHYIERDLAMFNINIDDDYVPCLQGITRASFCNVYLEWIQHCARKTQEPSK-
T---L

PF05041 // ENSGT00390000013164_1_Domain_0 (1866, 2098)

DSDEDSPLVTLSFALCTLGRRALGTAAHNMAISLDSFLYGLHALFKGDFRITARD
EWVFADMDLLHKVVAPAIR-----MSLKLHQDQFTCPDEYEDPAVLYEAIQSFEK-KVVI
CHEGDPAWRGAVLSNKEELLTLRHVVDEGADEYKVIMLHRSFLSFKVIKVNKECVRGLWA
GQQQELIFLRNRNPERGSIQNNKQVLRNLINSSCDQPLGYPMYVSPLTTSYLGTHKQLKN
VWGGPITLDRIRTWFWTKWVRMRKDCNARQ-QSGGNIEDM-DGGGTP---ATGGNNAPSG
GSQESSTEQPRKGGAQHGVSSC--EGTQRTG----RRKGRSQSVQAHSALSQRPPMLSSS
GPILESRQTFLQTSTSVHELAQRLSESRLSLHTSATSLHSQPPPVTTTGH-LSVRERAEA
LIRSSLGSSTSSTLSFLFGKRSFSSALVISGLSAAEGGNTSDTQSSSSVNIVMGPSARAA
SQATRHLSE-PCEPTDAT-EQGQLRDRRPAEAVAE-TLGVVCRR-ASQEDMGLDDTASQQ
SVSDEQ

------------------------------------------------------------
-------------------------MVSQVLQLLR-------QGVWAALTGGWYHDPEQS
KFTNSC--H-------LYLWLFLL-------LLP--------LALHLAFPPTVI----TA
LFYCSSVTLLFTVIKVVSYRLHLMFDKGEVIQQRSPGQMEKPKKGREAN--SEHATNPKI
PS--NTRPIHSSKKEEMGRSVPTPPLHCNSRGHSLSSHRSSG-PPDLPAQETVEDLKGVV
LSEDHPGAL-VSSTSPGIRTESLPASQMCLPEPVPRSAEPAKPVVPEALISGKGRGREG-
QGQ-RPPRHRSEGG-LVDKGDLKKLRRLSLSQYDLLETDVSFQPWGSENSVLI-PEPVTH
HQGSIREQLQRKSPQDSLSSS-CPQCHTVMAKPA-ERLAG--------------------
----TSSQVGLPFSQDVNSSDSEVAVTLIDTSQPGDPLSLHEPIKIVITMSSTPNS-TTE
VGSSLHLTVMGTEQVGPGSHTAPASPRVASPPDV-EHVLIPVITLELSEDGG--GSVTGP
EDLRSQRTPDRLRVE--DPDQCSS-----GEMGRAT---------------QAPTPPVAS
E-------AEGERDSQASLDPASCKSSHEKRHARVLSVDSGTDVFLSRSSTEVVSD-KEK
TIPTSKSDLEAKEGQIPNESNFLEFVSLLESINTSKVVASTQPQDPADQHGASE------
-ARGLR-----GGQKEEILEKEKLSGQD-----SKPEKADLQSQDRVGTSPVFTPPAKTA
MLFQGNRQRQIIYRVTSQQDSSVLQVISGPETSVQEEMSVDAMHVFVDEH-GEIKSCYLK
SGNQKEGSFQFPPSREDCASQGREVHLSSSSTTTCESPDPSSGDPAVSALQQQLLLMVAR
RTHSETPR-----------VCTQTRIL--CLKTN--------KLISYFPG----------
VSLCVLL---RTEDVKENVLAIVLSILVSLLGFLTLNRGFCRDLWVLLFCVVMASCQYSL
LK-----------SVQPDPASPIHGHNQIITYSRPIYFCVLCGLILLLDAGAKSRHPPRY
VVYGLKLFSPESLQTARDHLIVFLYCFPAISLLGLFPQINTFCTYLLEQIDMLLFGGSAV
SGIVSAV--YSVGRSVLAATLLHVFCFSAVK-EPWSTQHIPALFSAFCG-LLVALSYHLS
RQSSDPSVL-LSLFQCKLFPKFLHQSL---EESATDPLPQKMK--------DSVKDVLRS
DLVVCSVVAVLSFAVSASTVFLSLRPFLSVVLFALAGTVGLIT-HHLLPQLRKHHPWMWV
SHPVLKSKEYQQREVGDVAHLMWFERLYVWLQSFEKYILYPAIILNALTIDAFSISNYRR
LGTHWDIFLMII--AGMKLLRTSFCNPV--HQFIHLSFALIFFHFDYKDFSESFLLDFFM
VSILLSK--LGDLLHKLQFVLAYVAPWQMAWGSSFHVFAQLFAIPHIL--------S--T
STFATAVFSTPLSPFLGSVIFITSYARPVKFWEKNYNTR---RVDNSNTRLAVQIERDAG
GD-DNNLNSIFYEHLTRTLQESLCGDLVLGRWGNYSSGDCFILASDDLNAFVHLIEIGNG
LVTFQLRGLEFR-GTYCQQREVEAIMEGDEEDRGCCCCQPGHLPHLLSCNAAFHLRWLTW
EVTRTQYILEGYSIIDNNAATMLQVFDLRRILIRYYVKSIIYYMVTSPKLLSWVKNESLL
KSLQPFAKWHHIERDLAMFNINIDDDYVPCLQGITRASYCNVYLEWIQYCAGKRQEPSK-
T---L

PF05041 // ENSGT00390000013164_1_Domain_0 (1866, 2097)

DSDEDSPLVTLSFALCILGRRALGTAAHNMAMSLDSFLYGLHALFKGDFRITARD
EWVFADMDLLHKVVAPAVR-----MSLKLHQDQFTCPDEYEDPAVLYGAIQSFEQ-KVVI
CHEADPAWRGAVLSNREELLTLRHVVDEGTDEYKVIMLHRGFLSFKVIKVNKECVRGLWA
GQQQELIFLRNRNPERGSIQNNKQVLRNLINSSCDQPLGYPMYVSPLTTSYLGTHPQLRN
VWGGPVTLDRLRTWFRARWLSMRKDCNAG-QRSGGAIEDLDGGGAPSG------------
---DGSVEQPQKGGTQHWVSPRE--GAQRTG----CRKGRSQSVQAPSALSQRLPTLSSS
GPIVESRQAFLQTSTSVHELAPRPSGSRLSLHTSATSLHSQPPPVTTTGH-LSVRERAEA
LIRSSLGSSTSSTLSFLFGKRSFSSALVISGLSAAEGGNTSDTQSSSSVNIVMGPSARAA
GHSTRHFSE-PCDPTEAA-EQRQLRDQRLAEAVAE-NLGVMCRR-ASQEDMGLDDTASQQ
SASDEQ

------------------------------------------------------------
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------------------------------------SQEPSSGDQAASALQQQLLLMVAR
RTLSENPR-----------QTSQDPEDSSCSSAQRKLNR-QFYRFVIFPGKWIKVWYDRL
TLLALLD---RTEDIKENVFAVLLVILVSLLGFLTLNQGFCKDIWVLLFCLVMASCQYSL
LK-----------SVQPDPASPIHGHNKIIIYSRPVYFCILCGLILLLDAGSKDTNPPVY
TMYGLKLFSPRSLQSARDHVIVFLYCFPAISLLGLFPQINTFCIYLLEQIDMLLFGGSAA
AGFVSAL--YSISRSFVVLIVLYAFCFSAVK-EPWDAQHIPALFSAFCG-LLVALSYHLS
RQSSDPSVL-MSLIQCKYVPHYLRQRF---EDSSEDPLPEKMR--------ESVKEILKS
DLIVCTAAAVLSFAVSASTVFLSLRPFLSIVLFALAWTVGFVT-HYILPQLRKHHPWLWI
SHPILKSKEHHQREVRDAAHLMWFERLYVWLQCFEKYILYPAIILNALTIDAFSISKYKK
LGTHCDIILITV--AGMKLLRSSFCNPI--NQFVTLSFTVIFFRFDYRDISENFLLDFFM
MSICITE--LWDLLQKLQFIMTYIAPWQIAWGSSFHVFAQLFAIPHILYKSFSDSAMLFF
QTLAASVFSTPLSPFLGSVIFIASYARPIKFWEKNYNTK---RSDHSNTRLAIQIEKDAG
ND-DNNLNSIFYEHLTRSLQESLCGDLILGRWGNYNTGDCFILASDYLNAFVHLIEIGNG
LVTFQLRGLEFR-GTYCQQREVEAITEGDEDNEGCCCCKPGHLPHLLSCNAAFNLRWLTW
EITRTQYILEGYSIIDNNAATMLQVFDLRRILIRYYIKSIIYFTASSPKILDWIKDESIQ
KILQPYAKWHYIERDLAMFNVNIDEDYVPCLQGITRASFCSVYLDWIQFCARKRVEVP-F
SFSHL

PF05041 // ENSGT00390000013164_1_Domain_0 (1866, 2098)

DSDEDSPLVTLSFALCILGRRALGTASHNMAISLDSFLYGLHALFKGDFRIAAKD
EWVFADMDLLHKVVAPAIR-----MSLKLHQDQFTCPDEYEDPAVLYEAIQSFEE-KVVI
CHEGDPAWRSAVLSNREELLTLRHVVDEGADEYKVIMLHKSYLSFKVIKVNKECVRGLWA
GQQQELIFLRNRNPERGSIQNNKQVLRNLINSSCDQPLGYPMYVSPLTTSYLGTHSQLRN
IWGGPVSLDNIKKWFKSKWLRMRKDCHAAAHHERGNVEDVDSAGGSSSSN------NSTG
NSSQSSSSQPTRDGTPQLQTS-SQEVQQRAG----RRKPRSQSVQAHSALNQRPPASSHS
GPIVESRQPFIQTSTSAHEIAQRLSSSQLSFHNSATSVFSQSPAVPVAGQ-LTVQDRAAA
MLRSSLASSTSSTLSLLFGKRSFSSALVISGLSAADGGNTSDTQSSSSMNIAMGPSARAA
SQAARQVAE-TCEATDAT-EPRPQREAGPAHALFM-SQNLECRR-ASQEDMALEDTASQQ
SLSEEQ

------------------------------------------------------------
------------------------------------------------------------
-------------HIYLSIYL-YL-------INL--------SVTYLAFPPNAI----TA
FFYCTSVTIFFTIIKLVSYRLHLMFDKGEVIQQKPSGKKEKPNKDKEAD--KEHVTNHKI
PS--NNRQIHNGKKEEPHRSLSTPPLRCSSRGQSINSQHSSG-PLELPAQETVEDLKGVI
LSEDQVVAP-VSSTSPGIKMESSPACKACGPETTTTPAVPMKPVVAETRISDKGKERGS-
KGQ-PPFRHRSEGG-LVEKEALKKLPHLSLSQYDLLETDVSFQPWGSENSVLS-PEPVIC
AQGSLREQSRSQSPVDTLSSS-CPQCNTVIARPV-RQPPD--------------------
----APGHGDPPLTQEVDCSDSEVAVTLIDTSQPGDPLSLHEPIKIVITMSSTPNS-MTD
LESSLHLKVIGTERAGSKSDAEPAVPGVASPPNK-EQIRIPVITLELSEDGR--GGAVCP
EGNGSDRTLERLI-VEVSSNQCSG--YESGEGANATKDGSPSL-GVRCETAPPFSPHVIP
E-------LEGGKEGQANLDPSSCKTSHEKRHTRVLSVDSGTDVFLSKSSAEMIND-KEK
TMPTSKSDLEAKEGQIPNESNFLEFVSLLESINTSKLVASSQRNGPGDQNKDSGLLG---
-------DNRSHEKKEEIQESEKPNGHS-----SKHGKPDMQSQDHTSTSPVLTEPAKIT
TLFQGNRQRQIIYRVTSQQDSSVLQVISGPETSVQDEMSVDAMHVFIDEH-GEIRSCYLK
SGNQKEGPLQHQPSHYDSFSHAREMQISSSSTTTSESQDPSSGDPAVSALQQQLLLMVAR
RTQPETPR-----------HLSQDLEDSSCSSTQGKFNREQFYKFIIFPGKWIKVWYDRL
TLLALLD---RTEDVKENVLAVLLIVLVSLLGFLTLNQGFCKDMWVLLFCLVMASCQYSL
LK-----------SVQPDPASPIHGHNQIITYSRPIYFCVLCGLILLLNTGAKARHPPTY
VVYGLKLFSPRSLQSARDLLIVFLYCFPAISLLGLFPQINTFCIYLLEQIDMLFFGGSAV
SGLTSAV--YSVARSAAAAGLLHALCFSAVK-EPWSTQHIPALFSAFCG-LLVALSYHLS
RQSSDPSVL-LSFTHCKLLPKFLHQNL---EELAADPLPKKMK--------DSVKDVLKS
DLIICSVAAVLSFAVSASTVFLSLRPFLSVVLFALAGLVGSVT-HHMLPQLRKHHPWMWI
SHPVLKNREYQQREVRDAAHLMWFERLYVWLQCFEKYILYPAIILNALTIDAFSISNYRR
LGTHWDIFLMIV--AGMKLLRTSFCNP-A-HQFIYLGFTVIFFHFDYKDISESFLLDFFM
VSILFSK--LGDLLQKLQFVMTYVAPWQMAWGSSFHVFAQLFAVPHSA--------LLFF
QTIVTSIFSTPLSPFLGSVIFITSYVRPVKFWEKNYNTR---RVDNSNTRLVVQIEKDLG
ND-DNNLNSIFYEHLTRALQESLCGDLILGRWGNYSSGDCFILASDYLNAFVHLIEIGNG
LVTFQLRGLEFR-GTYCQQREVEAIMEGDEDDRGCCCCKPGHLPHLLSCNAAFHLRWLTW
EITRTQYILEGYSIIDNNAATMLQMFDLRRVLIRYYVKSIIYYMVTSPKLLSWIKNESLL
KSLQPFAKWHYIERDLAMFNINVDDDYVPCLQGITRASYCNVYLEWIQYCAQKRQ

PF05041 // ENSGT00390000013164_1_Domain_0 (1856, 2098)

EPSK-
N---LDSDEDSPLVTLSFALCLLGRRALGTAAHNMALSLDSFLYGLHALFKGDFRITARD
EWVFADMDLLHKVVAPAIR-----MSLKLHQDQFTCPDEYEDPGVLYEAIQSFEK-KVVI
CHEGDPAWRGAVLSNKEELLTLRHVVDEGTDEYKVIMLHRSFLNFKVIKVNKECVRGLWA
GQQQELIFLRNRNPERGSIQNNKQVLRNLINSSCDQPLGYPMYVSPLTTSYLGTHKQLQS
VWSGPVTLDGVRTWFRTKWLRVRKGCDSG-QRAAGNIDDVDGRPAP----SAGGSHAPGG
ESQESSTEQTRKEGTQHWSPRE---RTQRTG----RRKGRSQSVQAQGALSQRPAMLSSS
GPILESRQAFLQTSTSVHELAQRLSGSRRSLHTSAASLHSQPPPVTTTGH-LSVRERAEA
LIRSSLGSSTSSTLSFLFGKRSFSSALVISGLSAAEGGNTSDTQSSSSVNIVMGPSARAA
SQTTRHFSE-PCEPTEAT-EQGQRHNLRLAEATAE-NEGQLCRR-ASQEDMGLDDTASQQ
SASDEQ

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------FYKFIIFPGKWIKVWYDRL
TLLALLD---RTEDIKENVFAVLLIILVSLLGFLTLNQGFCKDIWLLLFCLVMASCQYSL
LK-----------SVQPDPASPIHKDNRNLAYIRKAYFIFFCPQLYLLESNSKSIDYSHL
KLATYIMSHHLLLLMSKDLLSVFLYCFPAISLLGLFPQINTFAIYLLEQIDMLVFGGSAA
AGTLSAI--YSISRSFVVAIVLYAFCFMAVK-EPWSTQHIPALFSAFCG-LLVAVSYHLS
RQSSDPSVL-MSFIRCKLFPHFLHPNL---EEMPSDPLPKKMR--------DSVKEILKS
DLIVCTVVAILSFAVSASTVFLSLRPFLSLILFALACAVGFVT-HYMLPQLRKHHPWMWI
SHPILKNKEYHQRELKDVAHLMWFERLYVWLQCLEKYILYPAIILNALTIDAFSISNYRR
LGGQLGVNQITI--AGMKLLRTSFCNPV--HHFVTLSFTVIFFQFDCKNLSESFLLDFFM
VSILFNK--LGDLLHKLQFVMTYVAPWQLAWGSSFHVFAQLFAIPHSA--------MLFF
QTVATSIFSIPLSPFLGSVIFITSYARPVKFWEKNYNTR---RVDNSNTRLAVQIEKDPG
ND-DNNLNSIFYEHLTRSLQVSLCGDLVLGRWGNYSSGDCFILASDYLNAFVHLIEIGNG
LVTFQLRGLEFR-GTYCQQREVEAIMEGDEDDRSCCCCKPGHLPHLLSCNAAFNLRWLTW
EITRTQYILEGYNIIDNNAATMLQVFDLRRILIRYYIKSIIYFTVSSPKLLSWIKNESIL
KSLQPFAKWHYIERDLAMFSINIDDDYVPCLQGITRASYCNVYLEWIQYCARKRRER---
----

PF05041 // ENSGT00390000013164_1_Domain_0 (1865, 2098)

LDSDEDSPLVTLSFALCIMGRRALGTASHNMAFSLDSFLYGLHALFKGDFRITPRD
EWVFADMDLLHKVVAPAIR-----MSLKLHQDQFTCLDEYEDPVVLYEAIQSFEK-KVVI
CHEGDPAWRSAVLSNKEELLTLRHVVDEGTDEYKVIMLHKSYLSFKVIKVNKECVRGLWA
GQQQELIFLRNRNPERGSIQNNKQVLRNLINSSCDQPLGYPMYVSPLTTSYLGTHSQMRN
VWGGPISLDNIKSWFLNKWLRMRKDCNAS-QHSGGNIEEVDSGGGTSAGSG----SNSSS
SSQESSVEQ---------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------

------------------------------------------------------------
-------------------------MVSQVLQLLR-------QGVWAALTGGWYHDPEQS
KFTNSC--H-------LYLWLFLL-------LLP--------LALHLAFPPNAI----TA
LSYCGSVTVLFAVIKVVSYRLHLMFDKGEVIQQRSPRQPEKPKKDREANPNVEHATNPKI
LS--NTRPIHNSKREEVGRSVPTPPLRCSSRGQSLSSHPFSL-----------WFASGVI
LSEDHPGAP-VSSTSPGIRTESLPASPGCVPEHKNATKCRK-------------------
-------------------------------------------RWFPSQ-----------
-SG---------------SQV-HQLCEELLWM------TG--------------------
----QEAS------QDL----------------WGWRKSLSEKFKWFVKI----------
-----------------------------------------------SVLGG--------
------------------LNTCF-------------------------------------
-------------------------GNA--------------------------------
---------------------------------------GTRL--PELMTESRC------
-GEQCFSDHYLQGRKEEILEKEKFRGQD-----AKPEKPDSQSQDHTGTSPVFTPPAKTA
ALFQGNRQRQIIYRVTSQQDSSVLQVISGPETSVQEEMSVDAVHVFMDEH-GEIKSCYLK
SGNQKEGSFQCPPSGETCAPQAREVHLSSSSTTTCESPDPSSGDPAVSALQQQLLLMVAR
RTHSETPR-----------HVSQDLEDSSCSSAAGKFNREQFYKLFIFPGKWIKVWYDRL
TLLALLD---RTEDVTENVLAIALSVLVSLLGFLTLNRGFCRDLWVLLFCVVMASCQYSL
LK-----------SVQPDPASPIHGHNQIITYSRPIYFCVLCGLILLLDAGAKSRHPPRY
VIYGLKLFSSESLQTARDHLIVFLYCFPAISLLGLFPQINTFCTYLLEQIDMLLFGGSAV
SGIVSAV--YSVGRSVLAASLLHVFCFSAVK-EPWSTQHIPALFSAFCG-LLVALSYHLS
RQSSDPSVL-LSFIQCRLFPKFLHQSL---EESATDPLPQKMK--------DSVKDILRS
DLVVCSVVAVLSFAVSASTVFLSLRPFLSVVLFALAGTVGLLT-HHLLPQLRKHHPWMWV
SHPVLKSKEYQQRDVTGVAHLMWFERLYVWLQCFEKYILYPAIILNALTIDAFSISNYRR
LGTHWDIFLMII--AGMKLLRTSFCNPV--HQFIHLSFAVIFFHFDYKDFSESFLLDFFM
VSILLSK--LGDLLHKLQFVLAYVAPWQMAWGSSFHVFAQLFAIPHIL--------S--S
STVATAVFSTPLSPFLGSVIFITSYARPVKFWEKNYNTR---RVDNSNTRLAVQMERDAG
GD-DNNLNSIFYEHLTRTLQESLCGDLVLGRWGNYSSGDCFILASDDLNAFVHLIEVGNG
LVTFQLRGLEFR-GTYCQQREVEAIMEGDEEDRGCCCCQPGHLPHLLSCNAAFHLRWLTW
EVTRTQYILEGYSIIDNNAATMLQVFDLRRVLIRYYIKSIIYYMVTSPKLLSWVKNESLL
KSLQPFAKWHHIERDLAVFSINIDDDYVPCLQGVTRASYCNVYLEWIQYCAGKRQEPSK-
T---L

PF05041 // ENSGT00390000013164_1_Domain_0 (1866, 2097)

DSDEDSPLVTLSFALCILGRRALGTAAHNMAMSLDSFLYGLHALFKGDFRITARD
EWVFADMDLLHKVVAPAIR-----MSLKLHQDQFTCPDEYEDPAVLYGAIQSFEQ-KVVI
CHEADPAWRGAVLSNREELLTLRHVVDEGTDEYKVIMLHRGFLSFKVIKVNKECVRGLWA
GQQQELIFLRNRNPERGSIQNNKQVLRNLINSSCDQPLGYPMYVSPLTTSYLGTHPQLRN
VWGGPVTLDSLRTWFRARWLSMRKDCNTG-QRGRGAIEDPDGGRAPSG------------
---DSGAEQPPKGGTQHWVSPRGGEGAQRTG----CRKGRSQSVQAPSA----LPTLSSS
GPIVEGRQAFLQTSTSVHELAPRPSGSRLSLHTSAASLHSQPPPVTTTGH-LSVRERAEA
LIRSSLGSSTSSTLSFLFGKRSFSSALVISGLSAAEGGNTSDTQSSSSVNIVMGPSARAA
GHATRHFSE-PCDPTEAA-EQGQLRDRRLAEAVAE-NLGVMCRR-ASQEDMGLDDTASQQ
SASDEQ

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
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----WDIFLMIT--AGMKLLRTSFCNPV--HQFINLSFTVLFFHFDYRDVSEGFLLDFFV
VSILFSKA-LGDLLHKLQFIMTYVAPWQMAWGSSFHVFAQLFAVPH--------SAVLFF
QALATSIFASPLSPFLGSVIFITSYVRPVKFWEKNYNTR---RVDNSNTRLAVQMERDLG
GD-DNNLNAIFYEHLTRTLQESLCGDLVLGRWGNYSSGDCFILASDDLNAFVHLIEIGNG
LVTFQLRGLEFR-GTYCQQREVEAIMDGDEDDRNCCCCQPGHLPHLLSCNAAFHLRWLAW
ETTRSQYILEGYSILDNNAATMLQVFDLRRLLIRYYVKSIIYYVATSPKLPSWTKDESLL
TSLQPFAKWHHIERDLALFNINIDDDYVPCLQGITRASYCSVYLEWIQYCARRGREXXX-
XXXXXXXXXXX

PF05041 // ENSGT00390000013164_1_Domain_0 (1872, 2089)

XXXXXXXXXXXXXXXXXXXXXX---XXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXX-----XXXXXXXDQFTCPEEYEDPAVLYEAIQSFEK-KVVI
SHEGDPAWRGAVLSNQAELLTLRHVVDEGADEYKVVMLHRGFLSFKVIKFNKECLPGLWR
-QQQELVFLRNSNLRPGRVKNREVLW-NXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXVRKDCNAGR-PSGGHIEDV-DGGGTP---PARGSHAPGA
DSRESSTEQPRKAGSQPWASSH--EGTQRTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXX-XXXXXXXXX
XXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXHFSE-PCYPTA-A-EQGQPHDRRLAEATVE-NLGV-CRR-ASQEDMGLDDTASQQ
SASDEQ

------------------------------------------------------------
-------------------------MASQVLQLLR-------QGVWAALTGGWYHDPEHS
KFTNSC--H-------LYLWLFLL-------LLP--------LTLHLAFPPNVL----TA
LFYCGSVTILFAIIKLVSYRLHLMFDKGEVIQRQSPRKKSKRRPEGEAS--NQRMASHKN
PS--NNRQIHSAKKEEPRGSLPTPPLRCSSRGQSVHSQR-SS-PLELPAQETVEDLKGVV
LSEDQPEAV-VSSTSPGIKSESLPASQGRTPEPTPRPAGPVKPVTTEILTGRKGKEPGG-
TGQ-RPARHRSESG-LVNTGALKKLPHLSLSQYDLLETDISFQPWGSEHSALI-PQCPSC
PQDPTRAQSQSRLPQDSLSSS-CGQHNTVLAKPT-EEEELT-------------------
---QTSGQVEPPLNQEVVDSDGEVAVTLIDNSQPGEPLSLHEPIKIVITMSSTPNS-TSD
LESSLHLKVTSSDRTSVRLDAEPSGPGVAGPADS-EQVRIPLITLELTEDGG-GRGISCP
EGNEGERTPERTQ-VM-SSAHCL----GCGSGDMDPTPRHA-----WESTPAPLTPRVDP
E-------SEESREGQANLDPASCKSGHEKRHTRVLSVDSATDVFLSRSPKEVASD-SEK
PIPTSKSDLEAKEGQIPNESNFLEFVSLLESINTSKVVASDS---AAEQKGADQGPA---
-------DHTSPGTKEEAVESGKPSGHD-----PKPGKADLPSQDRAVASPVLTQPAKTT
ALFQGSRQRQIIYRVTSQQDSSVLQVISGPETSVQEEMSLDAMHVFIDEH-GEIKSCYLK
SGNQKEGSSQHLPLNPDCASRAREILLSSSSTTTSDSPDPSSGDPAVSALQQQLLLMVAR
RTQSETPRH-----------VSQDLEDSSRSSAQGRFNREQFYKFIIFPGKWIKVWYDRL
TLLALLD---RTEDVKENVVAILLSVLVSLLGFLTLNRGFCRDLWVLLFCVVMASCQYSL
LK-----------YN------SEIGHNQIIAYSRPIYFCMLCGLILLLDAGAKARHPPSY
VVYGLKLFSPETLQSVRDHLIVFLCCFPVISLLGLFPQINTFCTYLLEQVDMLLFGGSAV
SGITSAV--YSVGRSVLVAALLHAFCFSAVK-EPWSTQHIPALFSAFCG-LLVALSYHLS
RQSSDPSVL-LSFVQCRFLPKCLHQDL---DESATDPLPQRMK--------DSVKDVLRS
DLVVCSAAAVLSFAVSASTVFLSLRPFLSIVLFALAGTVGLVT-HHLLPQLRKHHPWMWV
SHPVLKSKECQQREARDIAHLMWFERLYVWLQCFEKYLLYPAIVLNALTLDAFSISNYRR
LGTHWDIFLMIT--AGMKLLRTAFCNPV--HQFANLGFTVIFFHFDYKDISESFLLDFFM
VSIVSTK--LGDLLHKLQFVLAYVAPWQMAWGSSFHVFAQLFAIPHIL---SAYSAMLFF
QTFATSIFSTPLSPFLGSVIFITSYVRPVKFWERSYNTR---RVDNSNTRLAVQMERDPG
SD-DNNLNSIFYEHLTRTLQESLCGDLVLGRWGNYSSGDCFILASDDLNAFVHLIEIGNG
LVTFQLRGLEFR-GTYCQQREVEAIMEGDEDDRGCCCCKPGHLPHLLSCNAAFHLRWLTW
EITRTQYILEGYRIMDNNAATMLQVFDLRRVLVRYYVKSIIYYMVTSPKLLSWVKNEPLL
KSLQPFAKWHHIERDLAMFNINIDDDYVPCLQGITRASYCTVFLEWIQYCAGKRQELSK-
ALDPV

PF05041 // ENSGT00390000013164_1_Domain_0 (1866, 2097)

DSDEDSPLVTLSFALCIFGRRALGTAAHNMAMSLDSFLYGLHALFKGDFRVTARD
EWVFADMDLLHKVVVPAVR-----MSLKLHQDQFTCPDEYEDPAVLYEAIQSFEK-KVVI
CHEGDPAWRGAVLSNKEELLTLRHVVDEGADEYKVIMLHRGFLSFKVIKVNKECVRGLWA
GQQQELIFLRNRNPERGSIQNNKQVLRNLINSSCDQPLGYPMYVSPLTTSYLGTHKQLQS
VWGGPVTLDRVRTWFQTRWLRMRKDCSVGQRSG-GNIEDV-DGPAGP---AAGGRNAPSG
ESRDSNSEQARKGGTQQWASPR--GEGHRTG----RRKGRSQSVLAHSAISQRPPTLSSS
GPIVESHQAFLQTSSSVHELAQRPSGSRLSLHNSAASLHSQPPPVTTTGH-LSVRERAEA
LIRSSLGSSTSSTLSFLFGKRSFSSALVISGLSAAEGGNTSDTQSSSSVNIVMGPSARAA
SHAARHFSE-PCEPTDTP-EQGQLPDPRLAEAVAE-NLGMLCRR-ASQEDMGLDDTASQQ
SASDEQ

------------------------------------------------------------
-------------------------MVSQALQLLR-------QGVWAALTGGWYHDPEQS
RFTNSC--H-------LYLWLFLL-------LLP--------LALHLACPPNTV----TA
VLYCSSVAVVFTTIKLVSYRLHLMFDKGEVVRLRPVQQREEPARDREAR--GQRTATPKD
PRTAGGRGIGSSKKEEVLGSLATPPLRCSSRGQSLHSRHSSG-RSASVPSHHSGQSVSVL
------SVS-VSSRSSGVRSGSVTLS----------------------------------
----------IAGP---LGALRKKLPHLSLSQYDLLETDVSFQPWGSENSVLI-PEPTHH
PPGCTREPLQSTSPQGSLSSS-CPQCHTVTAKPA-EEPGDTSCQVD--------------
----------LP------RSDSEVAVTLIDTSQPGDPLSLHEPIRIVITMSSTPNS-TTD
LDSSLHLQPTGTHRTHLRSDTEPAAPGADSPLST-EQVRVPTITLELSEDRG--GGILGP
QGHRTEGSPE---------------------GWQMEPDCSPAQ-RPTWETAPTLLPDAAS
P-------SEGGSDGQAKLDPSSCK-----RHARVFSVDSGTDVFLSRHSADVAGD-KEK
TMPTSKSDLEAKEGQMPNESSFLEFVSLIESISTAKVVTPGQRKGPAEQSGDGRLPA---
-------GAARPGRKEEDLEREKPCGQD-----SKPGQPDSQQQDHASASPMPAQPARTA
ALFQGNRHRQIIYRVTSQQDSSVLQVISGPETSVQEEMSVDAMHVFIDGH-GEVRSCYLK
SGNQKEGSLQHPPSDSACVSQIQTIQTSSSSTTTSESPDPSSGDPAVSALQQQLLLMVAR
RTQSETPRH-----------VSPDLENSSCSSAQGKFNREQFYKFIIFPGKWIKVWYDRL
TLLALLD---RTEDIKENLLSILLSTLVSLLGFLTLNRGFCRDLWVLLFCLVMASCQYSL
LK-----------SVQPDPASPIHGHNQIITYSRPIYFCMLCGLILLLDAGAKARRPPSY
VVYGLQLFSAEFLQSARDHLIVFVYCFPVISLLGLFPQINTFCTFLLEQIDMLFFGGSAV
SGILSAV--YSVGRSASAAALLHLFCFNAVK-EPWSTQHIPALFSAFCG-LLVALSYHLS
RQSSDPTVL-LSFIQCRLFPKFLHQNL---EESASDPLPQKMK--------DSVRDVLRS
DFIVCSVVAVLSFAVSASTVFLSLRPFLSLVLFALAGAVGLVT-HHLLPQLRKHHPWMWI
SHPVLKSKEYQQREVRDVAHLMWFERLYVWLQCFEKYILYPAIILNALTIDAFSISNYRR
LGTHWDIFLMII--AGMKLLRTSFCNPV--HQFLNLSFTVIFFHFDYKDISESFLLDFFM
VSIVFSK--LGDLLHKIRFVLTYVAPWQMAWGSSFHVFAQLFAIPH--------SAVLLF
QAAATSIFSAPLSPFLGSVIFITSYVRPVKFWEKNYNTR---RVDNSNTRLAVQIERDPG
SD-DNNLNSIFYEHLTRTLQESLCGDLLLGRWGNYSSGDCFILASDDLNAFVHLIEIGNG
LVTFQLRGLEFR-GTYCQQREVEAIMEGDEDDRGCCCCKPGHLPHLLSCNAAFHLRWLAW
EVTRTQYILEGYSIIDNNAATMLQVFDLRRILIRYYIKSIIYYMAASPKLPSWVENESLL
KSLQPFSQWHHIERDLAMLNVNVDDDYVPCLQGITRASYCNVYLEWIQYCAGKREQVPS-
K--AL

PF05041 // ENSGT00390000013164_1_Domain_0 (1866, 2097)

DSDEDSPLVTLSFALCILGRRALGTAAHNMAISLDAFLHGLHALFKGDFRVTARD
EWVFADMDLLHKVVAPAIR-----MSLKLHQDQFTCPDEYEDPAVLYEAIQSFEK-KVVI
CHEGDPAWRGAVLSNREELLTLRHVVDEGADEYKVVMLHRGFLSFKVIKVNKECVRGLWA
GQQQELIFLRNRNPERGSIQNNKQVLRNLVNSSCDQPLGYPMYVSPLTTSYLGTHRQMKH
VWGGPVTLDRLRAWFRARWLSMRKDCSVGQ-HSRGNIEDV-DGGGAP---A-GGSCAPSG
DSRESSAEHARKGGPQHWTSSR--EGAQRTG----RRKGRSQSVQAHPALSQRPPALSSS
GPILESRQAFLQTSTSVHELAQRPSGSRLSLHTSDASLHSQPPPVTTTGH-LSVRERAEA
LIRSSLGSSTSSTLSFLFGKRSFSSALVISGLSAAEGGNTSDTQSSSSVNIVMGPSARAA
SQATRHFSE-PCEPSDAA-EQGQLHDGRLAEAVAE-NRGLICRR-ASQEDMGLDDTASQQ
SASDEQ

------------------------------------------------------------
-------------------------MVSQVLQLLR-------QGVWAALTGGWYHDPEQS
KFTNSC--H-------LYLWLFLL-------LLP--------LALHLAFPPNAI----LV
FFYCSSVTIFFTIIKLVSYRLHLMFDQGEVIRQKPSRKEEKPGRDKEAK--SEHTANHKN
PS--NNRQIHNGKKEEANRNLSTPPLHCSSRGQSITSHRSSG-PLELSGQETVEDLKGVI
LSEDHPIAP-VSSTSPGIKMESLPASQAHMLETTPKSAIPVKPVATETFISGKGKERGS-
KGQ-PPLRHRSEGG-LVDKGPLKTLPHLSLSQYDLLETDVSFPPWGSENSVLI-PEPVSC
PQGSIRERVQSTSPQDSLSSS-CPQCDTIVAKPV-EEPVDTSCQVDTSCQVDTSCQADTS
CQADTSCQVDLPLNQEVDSSDGEVAVTLIDTSQPGDPLSLHEPIKIVITMSSTPNS-MTD
LESSLHLKVVGTEKTSLKSGAEPTNRRAASSPNA-EQISIPVITLDLPEDGG--GDIPCP
EGNGSKRTPERLK-ARVSTNQCPG--YGSGEGESAAKDHSSSS-REPWESASQLIPDIAS
E-------SKVGKEGQINLDPSSCKSSNEKRHARGLSVDSGTDVFLSKSSAEIIND-KEK
TMPTSKSDLEAKEGQIPNESNFLEFVSLLESINTSKVAASNQLNGSAEPNEESGLLR---
-------DNCFQEKKEEILENEKLSGHN-----SKQGKPDLQSQDHASTSPVCTQPAKTM
AFFQGNRQRQIIYRVTSQQDSSVLQVISGPETSVQEEISVDAMHVFIDEH-GEIRSCYLK
SGNQKEGPLQPVPSNYDCVSQPREMQVSSSSTTTSESQDPSSGDPAVSALQQQLLLMVAR
RTQSETPRH-----------VSQDLEDSSCSSTQGKFNREQFYKFIIFPGKWIKVWYDRL
TLLALLD---RTEDVKENVLAILLIVLVSLLGFLTLSQGFCKDMWVLLFCLVMASCQYSL
LK-----------SVQPDPASPIHGHNQIITYSRPIYFCVLCGLILLLDTGAKARHPPRY
VVYGLKLFSPVFLQSARDSLIVFLYCFPAMSLLGLFPQINTFCIYLLEQVDMLFFGGSAV
SGITSAV--YSVARSILAAALLHPVCFSAVK-EPWSTQHIPALFSAFCG-LLVALSYHLS
RQSSDPSVL-MSFMQCRLFPKFLHQNL---EESSADPLPKKMK--------DSVMDVLKW
DLVVCAVVAVLSFAVSASTVFLSLRPFLSIVLFALAGAVGFVT-HYLLPQLRKHHPWMWI
SHPILKNKEYHQRELKDVAHLMWFERLYVWLQCFEKYILYPALILNALTIDAFSISNHRR
LGTHWDIFLMITA--GMKLLRTSFCNPG--YQFINLSFTVIFFHFDYKDISESFLLDFFM
VSILFSK--LGDLLHKLQFVLTYVAPWQMAWGSSFHVFAQLFAIPH--------SAMLFF
QTIATSIFSTPLSPFLGSVIFITSYVRPVKFWEKNYNTR---RVDNSNTRLAVQIERDPG
ND-DNNLNSIFYEHLTRTLQESLCGDLLLGRWGNYSSGDCFILASDDLNAFVHLIEIGNG
LVTFQLRGLEFR-GTYCQQREVEAIMEGDEEDRGCCCCKPGHLPHLLSCNAAFHLRWLTW
EITRTQYILEGYSILDNNAATMLQVFDLRRILIRYYIKSIIYYMVTSPKLFSWIKNESLL
KSLQPFAKWHYIERDLAIFNINTDDDYVPCLQGITRASFCNVYLEWIQHCARKRQEPSK-
T---L

PF05041 // ENSGT00390000013164_1_Domain_0 (1866, 2097)

DSDEDSPLVTLSFALCTLGRRALGTAAHNMAISLDSFLYGLHALFKGDFRVTARD
EWVFADMDLLHKVVAPAIR-----MSLKLHQDQFTCPDEYEDPAVLYEAIQSFEK-KVVI
CHEGDPAWRGAVLSNKEELLTLRHVVDEGADEYKVLMLHRSFLSFKVIKVNKECVRGLWA
GQQQELIFLRNRNPERGSIQNNKQVLRNLINSSCDQPLGYPMYVSPLTTSYLGTHRQLKN
VWGGPITLDRIRTWFWTKWVRMRKDCNARQ-HSAGNIEDV-DGGGVP---TTGGDNAPSG
GSQESSAEQPRKDGFQHGVSSC--EGTQRTG----RRKGRSQSVQAHSTLSQRPPMLSSS
GPILESRQPFLQTSTSVHELAQRLSGSRLSLHTSATSLHSQPPPVTTTGH-LSVRERAEA
LIRSSLGSSTSSTLSFLFGKRSFSSALVISGLSAAEGGNTSDTQSSSSVNIVMGPSARAA
SQATRHLSE-PCEPTDTT-EQGQVRDHRLAEAVAE-TLRVVCRR-ASQEDMGLDDTASQQ
SASDEQ

------------------------------------------------------------
-------------------------MVSQALQLLR-------QGVWAALTGGWYHDPEQS
KFTNSC--H-------LYLWLFLL-------LLP--------LALHLAFPPNAI----TV
FFYCSSVTIFFTVIKLVSYRLHLMFDKGEVIQQRPPRKKEKPHKDKEAN--SEHITNHKH
PS--NNRQINNGKKEEANCNLTTPPLHCGSRGQSINSHHSSG-LLELAAQETVEDLRGVI
LSEDQPVAP-VSSTSPCVRRENLPVSKVYMPETMATSAIPTKPVTTETLLSNKVKGRGG-
KVQ-PPFRHRSEGR-LEDKDALTKLPHLSLSQYDLLETDVSFHPCGSENSVLI-PEPTHH
PKGSIREQLQSKSPQDRLSSS-CPQCNTVITRQV-EELLD--------------------
----TSCQVDPPLDEEVNYSDSEVAVTLIDTSQPGDPLSLHEPIKIVITMSSTPNS-MTD
LESSLHLKVISTERNAPKLDAEPATQGVASPPNG-EQMRIPVITLELSEDGQ--GGTICP
EGNGSERTPERLM-VEESSNQCSG--YESGEGGNATKDYSPSP-RDHCEATPLLTPNMAS
E-------SVGGREGQANLDPSSCRNSQEKRHARVLSVDSGTDVFLSKSAAEVTND-KEK
TMPTSKSDLEAKEGQIPNESNFLEFVSLLESINTSKVVAANQSNGSTEHNKESRLLG---
-------DICSQEKKEEILESEKPSGHN-----SRQGKLDVQSQDHTNTSPVFTEPAKIT
ALFQGNRQRQIIYRVTSQQDSSVLQVVSGPETSVQDEISVDAMHVFIDEH-GEIRSCYLK
SGNQKEGPLQHQPSNYDWFSNTREVQSSSSSTTTSESQDPSSGDPAVSALQQQLLLMVAR
RTQSETPR-----------HRSQDLEDSSCSSTQGKFNREQFYKLIIFPGKWIKVWYDRL
TLLALLD---RTEDIKENVLAVLLIVLVSLLGFLTLNQGFCKDMWILLFCLVMASCQYSL
LK-----------SVQPDPASPIHGHNQIITYSRPIYFCLLCGLILLLDTGAKARHPPTY
AVYGLKLFSPGSLQSTRDHLIAFLYCFPAISLLGLFPQINTFCVYLLEQIDMLFFGGSAV
SGMLSAV--YGVARSCAAAAALHALCFSAVK-EPWSTQHIPALFSAFCG-LLVALSYHLS
RQSSDPSVL-MSFIQCKLFPKFLHQSL---DELAEDPLPKKMK--------DSVKDALQS
DLIVCSVVAVLSFAVSASTVFLSLRPFLSIVLFVLAGTVGFLA-HYLLPQLRKHHPWMWI
SHPILKNREYQQREVTDIAHLMWFERLYVWLQCFEKYILYPAIILNALTIDAFAISNYRR
LGTHWNIFLMII--AGMKLLRTSFCNP-V-HQFVTLSFTVIFFHFDYKDISESFLLDFFM
MSILFSK--LGDLLHKLQFIMTYVAPWQMAWGSSFHVFAQLFAIPHSA--------MLFF
QTIATSIFSAPLSPFLGSVIFITSYVRPVKFWEKNYNTR---RVDNSNTRLAVQIEKDPG
AD-DNNLNSIFYEHLTRALQESLCGDLVLGRWGNYSSGDCFILASDYLNAFVHLIEIGNG
LVTFQLRGLEFR-GTYCQQREVEAIMEGDEDDRGCCCCKPGHLPHLLSCNAAFNLRWLTW
EITRTQYILEGYSIIDNNAATMLQVFDLRRILIRYYIKSIIYYMVTSPKLLSWIKNESLL
KSLQPFAKWHYIERDLAMFSINVDDDYVPCLQGITRASYCNVYLEWIQYCARKQQ

PF05041 // ENSGT00390000013164_1_Domain_0 (1856, 2098)

EPSK-
T---LDSDEDSPLVTLSFALCILGRRALGTAAHNMALSLDSFLYGLHALFKGDFRITARD
EWVFADMDLLHKVLAPAIR-----MSLKLHQDQFTCPDEYEDPVVLYEAIQSFER-KVVI
CHEGDPAWRSAVLSNREELLTLRHVVDEGTDEYKVIMLHKSFLSFKVIKVNKECVRGLWA
GQQQELIFLRNRNPERGSIQNNKQVLRNLINSSCDQPLGYPMYVSPLTTSHLGTHRQLKD
VWGGPVSLDRIQTWFRTKWLRMRKDCHAG-QHSGGNIEDVDGGGAPSTGH------TTSG
ESQESSAEPPRKDGHRDGVPM--AGGCREGG----RKKGRSQSVQAHEALSQRPPILSLS
GPILDSHQPFIQKSTSVHELAPRLSSSQLSLHNSAVSLHSQPPPATTTGH-LSVRERAEA
LIRSSLGSSTSSTLSFLFGKRSFSSALVISGLSAAEGGNTSDSQSSSSVNIVMGPSARAS
GQATRHFSE-PCEPTDAM-EQGQLCDRSLAEALAE-NLRVMCRR-ASQEDMGLDDTASQQ
SASDEQ

------------------------------------------------------------
-------------------------MVSQVLQLLR-------QGVWAALTGGWYHDPEQS
KFTNSC--H-------LYLWLFLL-------LLP--------LALHLAFPPNAI----IV
FFYCSAVTIFFTIIKLVSYRLHLMFDKGEVIQQKPSRKEEKPNKDKEAK--GEHITNHRN
PS--NNRQIHNGKKEEASRNLSTPPLRCSSRGQSITSHHSSG-PLELSAQETVEDLKGVI
LLEDHPIAP-VSSTSPGIKVESLPASQAHMLETTTKSVIPVKPVATETLINGKGKERGG-
KGQ-PPLRHRSEGG-LVDKGPLKKLPHLSLSQYDLLETDVSFQPWGSENSVLI-PEPVSC
PRGSIRERVQSKSPQDSLSSS-CPQCDTIVAKPV-EEPADTSCQVD--------------
----TSCQGDLPLHQEVDSSDSEVAVTLIDTSQPGDPLSLHEPIKIVITMSSTPNS-MTD
LESSLHLRVVGTEKTSVKSDAEPTNPGAAGSPNA-EQISIPVITLDLPEGGG--GGVPCP
EGNGSERTPERLK-TRVSTNQCSG--YGSGEGGNAIKDHSSSS-REPWESVSRLTPDTGS
E-------SKVGKEGQTNLDPSSCKSSHEKRHARVLSVDSGTDVFLSKSSAEIVND-TEK
TMPTSKSDLEAKEGQMPNESNFLEFVSLLESINTSKMTASSQLNGSAEQNEESGLLR---
-------DNCSQEKKEEILENEKPSGHS-----SKQGKPDLQSQDHTSTGPACTQPAKTT
AFFQGNRQRQIIYRVTSQQDSSVLQVISGPETSVQEEISVDAMHVFIDEH-GEIRSCYLK
SGNQKEGPLQPLPSNNDCLSQAREMQVSSSSTTTSESQDPSSGDPAVSALQQQLLLMVAR
RTQSETPRH-----------VSQDLEASSCSSTQGKFNREQFYKFIIFPGKWIKVWYDRL
TLLALLD---RTEDIKENVLAILLIVLVSLLGFLTLSQGFCKDMWVLLFCLVMASCQYSL
LK-----------SVQPDPASPIHGHNQIITYSRPIYFCVLCGLILLLDTGAKARHPPSY
VVYGLKLFSPVFLQSARDYLIVFLYCFPAISLLGLFPQINTFCTYLLEQIDMLFFGGSAV
SGITSAV--YSVARSVLAAALLHAVCFSAVK-EPWSMQHIPALFSAFCG-LLVALSYHLS
RQSSDPSVL-MSFIQCRLFPKFLHQNL---AESAADPLPKKMK--------DSVTDVLKW
DLIVCAVVAVLSFAVSASTVFLSLRPFLSIVLFALAGAVGFVT-HYVLPQLRKHHPWMWI
SHPILKNKEYHQREVRDVAHLMWFERLYVWLQCFEKYILYPALILNALTIDAFLISNHRR
LGTHWDIFLMIIA--GMKLLRTSFCNPV--YQFINLSFTVIFFHFDYKDISESFLLDFFM
VSILFSK--LGDLLHKLQFVLTYVAPWQMAWGSSFHVFAQLFAIPH--------SAMLFF
QTIATSIFSTPLSPFLGSVIFITSYVRPVKFWEKNYNTR---RVDNSNTRLAVQIERDPG
ND-DNNLNSIFYEHLTRTLQESLCGDLVLGRWGNYSSGDCFILASDDLNAFVHLIEIGNG
LVTFQLRGLEFR-GTYCQQREVEAIMEGDEEDRGCCCCKPGHLPHLLSCNAAFHLRWLTW
EITQTQYILEGYSILDNNAATMLQVFDLRRILIRYYIKSIIYYMVTSPKLLSWIKNESLL
KSLQPFAKWHYIERDLAMFNINIDDDYVPCLQGITRASFCNVYLEWIQHCARKRQEPST-
T---L

PF05041 // ENSGT00390000013164_1_Domain_0 (1866, 2097)

DSDEDSPLVTLSFALCTLGRRALGTAAHNMAISLDSFLYGLHVLFKGDFRITARD
EWVFADMDLLHKVVAPAIR-----MSLKLHQDQFTCPDEYEDPAVLYEAIQSFEK-KVVI
CHEGDPAWRGAVLSNKEELLTLRHVVDEGADEYKVIMLHRSFLSFKVIKVNKECVRGLWA
GQQQELIFLRNRNPERGSIQNNKQVLRNLINSSCDQPLGYPMYVSPLTTSYLGTHRQLKN
IWGGPITLDRIRTWFWTKWVRMRKDCNARQ-HSGGNIEDV-DGGGAP---TTGGNNAPSG
GSQESSAEQPRKGGAQHGVSSC--EGTQRTG----RRKGRSQSVQAHSALSQRPPMLSSS
GPILESRQTFLQTSTSVHELAQRLSGSRLSLHASATSLHSQPPPVTTTGH-LSVRERAEA
LIRSSLGSSTSSTLSFLFGKRSFSSALVISGLSAAEGGNTSDTQSSSSVNIVMGPSARAA
SQATRHLSE-PCEPPDAT-EQGQLHDRCLAEAVAD-TLGVVCRR-ASQEDMGLDDTASQQ
SVSDEQ

------------------------------------------------------------
-------------------------MASQVLQLLR-------QGVWAALTGGWYHDPEHS
KFTNSC--H-------LYLWLFLL-------LLP--------LALHLAFPPNVL----TA
LFYCGLVTIFFAAIKIISYRLHLMFDKGEVVQHRSPRKRSKRRPEGEAS--SQHTASHKN
PS--NNRQLHSAKKEEPRGSLPTPPLRCSSRGQSVHSRH-SS-PLELPAQETVEDLKGVV
LSEDQPEAV-VSSTSPGIKSESLPASQGHTPELTPRPTEPVKRVTTETLTGRKGKEPGA-
TGQ-RPARHRSESG-LVNTGALKKLPHLSLSQYDLLETDISFQPWGSEHSALI-PQTTSC
PQGPTRAQSQSRSPQDSLSSS-CCQCNTVLAKPT-EEEELT-------------------
---RTSGQVELPLNQEVVDSDGEVAVTLIDTSQPGEPLSLHEPIKIVITMSSTPNS-MSD
LESSLQMKVTSSDGTNVRPDAEPSGPGVASPTDP-EQIRIPLITLELTEDGR-ERSISCP
ERNGGERTPERME-RM-PSDLCS----GCGSGDQDA------------------TSRVDP
E-------SEGSREGQANLDPTSCKSSHEKRHARVLSVDSGTDVFLSRSTKEAVSD-SEK
PIPTSKSDLEAKEGQIPNESNFLEFVSLLESINTSKVVAPNS---GAEQKEANQGPE---
-------DHASPGTKEETVESEKPSGHD-----PKPGKPDLPSQDHAIASPVFTQPAKTT
ALFQGSRQRQIIYRVTSQQDSSVLQVISGPETSVQEEMSLGAMHVFIDEH-GEIKSCYLK
SGNQKEGSSQHPPLNPDCVSRAREILLSSSSTTTSESPDPSSGDPAVSALQQQLLLMVAR
RTQSETPRH-----------MSQDLEDSSRSSAQGKFNREQFYKFIIFPGKWIKVWYDRL
TLLALLD---RTEDVKENVVAILLSVLVSLLGFLTLNRGFCRDLWVLLFCLVMASCQYSL
LK-----------SVQPDPASPIHGHNQIIAYSRPIYFCMLCGLILLLDAGAKARHPPSY
VVYGLKLFSPETLQSIRDHLIVFLCCFPVISLLGLFPQINTFCTYLLEQVDMLLFGGSAV
SGITSAV--YSVGRSVLVAALLHAFCFSAVK-EPWSTQHIPALFSAFCG-LLVALSYHLS
RQSSDPSVL-LSFIQCRLLPKFLHQNL---EESATDPLPQRMK--------DSVKDVLRS
DLVICSAAAVLSFAVSASTVFLSLRPFLSIVLFALAGTVGLIT-HHLLPQLRKHHPWMWV
SHPVLKSKECQQREARDIAHLMWFERLYVWLQCFEKYLLYPAIVLNALTLDAFSISNYRR
LGTHWDIFLMIT--AGMKLLRTSFCNPV--HQFANLGFTVIFFHFDYKDISESFLLDFFM
VSIVFTK--LGDLLHKLQFVLAYVAPWQMAWGSSFHVFAQLFAIPH--------SAMLFF
QTFATSIFSTPLSPFLGSVIFITSYVRPVKFWERSYNTR---RVDNSNTRLAVQMERDPG
SD-DNNLNSIFYEHLTRTLQESLCGDLVLGRWGNYSSGDCFILASDDLNAFVHLIEIGNG
LVTFQLRGLEFR-GTYCQQREVEAIMEGDEDDRGCCCCKPGHLPHLLSCNAAFHLRWLTW
EITRTQYILEGYRIIDNNAATMLQVFDLRRVLVRYYVKSIIYYMVTSPKLLSWVKNEPLL
KSLQPFAKWHHIERDLAMFNVNIDDDYVPCLQGITRASYCTVFLEWIQYCAGKRQELSK-
ALDHV

PF05041 // ENSGT00390000013164_1_Domain_0 (1866, 2097)

DSDEDSPLVTLSFALCILGRRALGTAAHNMAMSLDSFLYGLHALFKGDFWVTARD
EWVFADMDLLHKVVVPAIR-----MSLKLHQDQFTCPDEYEDPAILYEAIQSFEK-KVVI
CHEGDPAWRSAVLSNKEELLTLRHVVDEGADEYKVIMLHRGFLSFKVIKVNKECVRGLWA
GQQQELIFLRNRNPERGSIQNNKQVLRNLINSSCDQPLGYPMYVSPLTTSYLGTHKQLQS
VWGGPVTLNRMRTWFQTRWLRMRKDCSVGQRSG-GNIEDV-DGGAVP---AAVGSNAPSG
ESRDSSTEQPRKGGTQQWASPR--GGGHRAG----RRKGRSQSVQAHSAISQRPPTLSSS
GPILESHQAFLQTSSSVHELAQRPSSSRLSLHTSAASLHSQPPPVTTTGH-LSVRERAEA
LIRSSLGSSTSSTLSFLFGKRSFSSALVISGLSAAEGGNTSDTQSSSSVNIVMGPSARAA
GHATRHFSE-PCEPTDTP-EQGQLQDRRQAEAVAE-NLGVLCRR-ASQEDMGLDDTASQQ
SASDEQ

------------------------------------------------------------
-------------------------MVSQVLQLLR-------QGVWAALTGGWYHDPEHS
KFTNSC--H-------LYLWLFLL-------LLP--------LALHLAFPPNAI----TV
FFYCSSVTIFFTVIKLVSYRLHLMFDKGEVIQQKPSRKKEKPNKGKEAN--SEHITNHKI
PS--NNRQIHNGKKEEGNRNLSTPPLRCSSRGQSINSHHSSG-PSELPAQETVEDLKGVV
LSEDQPVPP-ESSTSPGIKTESLPASQVRVPETTPKSATPVKPVATGTLTSGKGKERGS-
KGR-PPLRHRSEGG-LVDKGPLKKLPHLSLSQYDLLETDVSFQPWGSENSVLI-PEPPSC
PQGSMRGQLQSRSPQDSLSSS-CPQCNTVTVKPA-EEPVD--------------------
----TSCQVDLPLSQEVNCSDSEVAVTLIDNSQPGDPLSLHEPIKIVITMSSTQNS-MTD
LESPLHLKVVSTERTGLRSDAEPAAPAVATPPNAAEQVRIPVITLELSEDGG--RGMACP
EGNGGGRVSERSK-AEASSNQCSS--HRSGVGEGATKDCSPSS-RNPWETAPPLTPAVAS
E-------SEMGKEGQANLDPSSCNNSHEKRHARVLSVDSGTDVFLSKSSAEVIND-KEK
TMPTSKSDLEAKEGQLPNESNFLEFVSLLESINTSKVVAPNPSNGSAEQKEESGLLRGAI
PHQFCSEDNCSQEKKEEILESEKPTGQN-----SKQGKPDLQSQDHTGTSPLFTQPAKTP
AFFQGNRQRQIIYRVTSQQDSSVLQVISGPETSVQEEISVDAMHVFIDEH-GEIRSCYLR
SGNQKEGPLQHPPSNCDRPSQAGEMHVSSSSTTTSESQDPSSGDPAVSALQQQLLLMVAR
RTQSETPR-----------HVSRDLEDSSCSSTQGKFNREQFYKFIIFPGKWIKVWYDRL
TLLALLD---RTEDVKENVLAVLLIVLVSLLGFLTLNRGFCKDMWVLLFCLVMASCQYSL
LK-----------SVQPDPASPIHGHNQIITYSRPIYFCVLCGLILLLDTGAKARHPPRY
VVYGLKLFSPVSLQSARDYLIVFLYCFPAISLLGLFPQINTFCIYLLEQIDMLFFGGSAV
SGITSAV--YSVARSVLAAALLHAVCFSAVK-EPWSMQHIPALFSAFCG-LLVALSYHLS
RQSSDPSVL-MSFIQCKLFPKFLHENL---EESVADPLPKKMK--------DSVKDVLKS
DLIVCGIAAVLSFAVSASTVFLSLRPFLSIVLFALAGSVGFVT-HYLLPQLRKHHPWMWI
SHPVLKSKEYHQRELRDVAHLMWFERLYVWLQCFEKYVLYPAIILNALTIDAFSISNYRR
LGTHWDIFLMII--AGMKLLRTSFCNP-V-HQFVNLSFTVIFFHFDYKDISESFLLDFFM
VSILFSK--LGDLLHKLQFVMTYVAPWQMAWGSSFHVFAQLFAIPHSA--------MLFF
QTIATSIFSTPLSPFLGSVIFITSYVRPVKFWEKNYNTR---RVDNSNTRLAVQIERDPG
ND-DNNLNSIFYEHLTRTLQESLCGDLILGRWGNYSSGDCFILASDDLNAFVHLIEIGNG
LVTFQLRGLEFR-GTYCQQREVEAIMEGDEDDRGCCCCKPGHLPHLLSCNAAFHLRWLTW
EITQAQYILEGYSIIDNNAATMLQVFDLRRILIRYYVKSIIYYMVTSPKLLSWIKNESLL
KSLQPFAKWHYIERDLAMFNINIDDDYVPCLQGITRASFCNVYLEWIQYCARKRQEPAK-
TV--V

PF05041 // ENSGT00390000013164_1_Domain_0 (1866, 2097)

DSDEDSPLVTLSFALCVLGRRALGTAAHSMAISLDSFLYGLHALFKGDFRVTARD
EWVFADMDLLHKVVAPAIR-----MSLKLHQDQFTCPDEYEDPAVLYEAIQSFEK-KVVI
CHEGDPAWRGAVLANKEELLTLRHVVDEGTDEYKVIMLHRSFLSFKVIKVNKECVRGLWA
GQQQELIFLRNRNPERGSIQNNKQVLRNLINSSCDQPLGYPMYVSPLTTSYLGTHRQLKN
VWGGPVTLNRVRTWFQTKWLRMRKDCNAR-QHSSGNIEDADGGGAP----VAGGGNAPGG
GSQDGSAEQPRKGGSQPRASSH--EGTQGTG----RRKGRSQSVQAHSALGQRPPVLSSS
GPILESRQAFLQTSSSVHELAQRLSGSRLSLHTSAASLHSQPPPATTTGH-LGVRERAEA
LIRSSLGSSTSSTLSFLFGKRSFSSALVISGLSAAEGGNTSDTQSSSSVNIVMGPSARAT
SQPRRHFSE-PCEPTDAT-EQGQLRDRRLAEAVAE-TLGVICRR-ASQEDMGLDDTASQQ
SASDEQ

------------------------------------------------------------
-------------------------MVSQVLQLLR-------QGVWAALTGGWYHDPEQS
KFTNSC--H-------LYLWLFLL-------LLP--------LALHLAFPPNAI----IV
FFYCSAVTIFFTIIKLVSYRLHLMFDKGEVIQQKPSRKEEKPNKDKEAK--GEHITNHKN
PS--NNRQIHNGKKEEASRNLSTPPLRCSSRGQSITSHHSSG-PLELSAQETVEDLKGVI
LLEDHPIAP-VSSTSPGIKMESLPASQAHMLETTPKSVIPVKPFATETLINGKGKERGG-
KGQ-PPLRHRSEGG-LVDKGPLKKLPHLSLSQYDLLETDVSFQPWGSENSVLI-PEPVSC
PQGSVRERVQSKSPQDSLSSS-CPQCDTIVAKPV-EEPADTSCQVD--------------
----TSCQVDLPLHQEVDSSDSEVAVTLIDTSQPGDPLSLHEPIKIVITMSSTPNS-MTD
LESSLHLRVVGTEKTGVKSDAEPTNPGAAGSPNA-EQISIPVITLDLPEGGG--GGVPCP
KGNGSERTPERLK-TRVSTNQCSG--YGSGEGGNAIKDHSSSS-REPWESVSRLTPDTAS
K-------SKVGKEGQTNLDPSSCKSSHEKRHARVLSVDSGTDVFLSKSSAEIVND-TEK
TMPTSKSDLEAKEGQMPNESNFLEFVSLLESINTSKMTASNQLNGSAEQNEESGLLR---
-------DNCSQEKKEEILENEKPSGHS-----SKQGKPDLQSQDHTSTGPACTQPAKTT
AFFQGNRQRQIIYRVTSQQDSSVLQVISGPETSVQEEISVDAMHVFIDEH-GEIRSCYLK
SGNQKEGPLQPLPSNSDCLSQAREMQVSSSSTTTSESQDPSSGDPAVSALQQQLLLMVAR
RTQSETPRH-----------VSQDLEASSCSSTQGKFNREQFYKFIIFPGKWIKVWYDRL
TLLALLD---RTEDIKENVLAILLIVLVSLLGFLTLSQGFCKDMWVLLFCLVMASCQYSL
LK-----------SVQPDPASPIHGHNQIITYSRPIYFCVLCGLILLLDTGAKARHPPSY
VVYGLKLFSPVFLQSARDYLIVFLYCFPAISLLGLFPQINTFCTYLLEQIDMLFFGGSAV
SGITSAV--YSVARSVLAAALLHAVCFSAVK-EPWSMQHIPALFSAFCG-LLVALSYHLS
RQSSDPSVL-MSFIQCRLFPKFLHQNL---EESAADPLPKKMK--------DSVADVLKW
DLIVCAVVAVLSFAVSASTVFLSLRPFLSIVLFALAGAVGFVT-HYVLPQLRKHHPWMWI
SHPILKNKEYHQREVRDVAHLMWFERLYVWLQCFEKYILYPALILNALTIDAFLISNHRR
LGTHWDIFLMIIA--GMKLLRTSFCNPV--YQFINLSFTVIFFHFDYKDISESFLLDFFM
VSILFSK--LGDLLHKLQFVLTYVAPWQMAWGSSFHVFAQLFAIPH--------SAMLFF
QTIATSIFSTPLSPFLGSVIFITSYVRPVKFWEKNYNTR---RVDNSNTRLAVQIERDPG
ND-DNNLNSIFYEHLTRTLQESLCGDLVLGRWGNYSSGDCFILASDDLNAFVHLIEIGNG
LVTFQLRGLEFR-GTYCQQREVEAIMEGDEEDRGCCCCKPGHLPHLLSCNAAFHLRWLTW
EITQTQYILEGYSILDNNAATMLQVFDLRRILIRYYIKSIIYYMVTSPKLLSWIKNESLL
KSLQPFAKWHYIERDLAMFNINIDDDYVPCLQGITRASFCNVYLEWIQHCARKRQEPST-
T---L

PF05041 // ENSGT00390000013164_1_Domain_0 (1866, 2097)

DSDEDSPLVTLSFALCTLGRRALGTAAHNMAISLDSFLYGLHALFKGDFRITARD
EWVFADMDLLHKVVAPAIR-----MSLKLHQDQFTCPDEYEDPAVLYEAIESFEK-KVVI
CHEGDPAWRGAVLSNKEELLTLRHVVDEGADEYKVIMLHRSFLSFKVIKVNKECVRGLWA
GQQQELIFLRNRNPERGSIQNNKQVLRNLINSSCDQPLGYPMYVSPLTTSYLGTHRQLKN
VWGGPITLDRIRTWFWTKWVRMRKDCNARQ-HSGGNIEDV-DGGGAP---RTGGNNAPSG
GSQESSAEQPRKGGAQHGVSSY--EGTQRTG----RRKGRSQSVQAHSALSQRPPMLSSS
GPILESRQTFLQTSTSVHELAQRLSGSRLSLHASATSLHSQPPPVTTTGH-LSVRERAEA
LIRSSLGSSTSSTLSFLFGKRSFSSALVISGLSAAEGGNTSDTQSSSSVNIVMGPSARAA
SQATRHLSE-PCEPPDAT-EQGQLCDRRLAEAVAD-TLGVVCRR-ASQEDMGLDDTASQQ
SVSDEQ

------------------------------------------------------------
-------------------------MVSQVLQLLR-------QGVWAALTGGWYHDPEQS
KFTNSC--H-------LYLWLFLL-------LLP--------LALHLALPPNAI----TV
FFYCSSVTIFFTIIKLVSYRLHLMFDKGEIIQQQPSRKKDEPDKDK-SN--SEHITNCKN
PS--NNRQINNGKKEEVSRILTTPPLRCSSLGQSTNSHHSSG-LLEFPAQETVEDLRGVI
LSEEQPVAP-TSSTSPCVQRENLPVSKVCMPETIAMSAIPMKPVSRETLLNNKVKERGG-
KVQ-PPFCHRSEGG-LEDKDGLKKLPHLSLSQYDLLETDVSFHPWGSENSVLI-PEPGQH
PKGSIREQLQSKSPPDSLSSS-CPQCNTVIARQM-EEVGD--------------------
----TSSQVDPPLDEEVHYSDSEVAVTLIDTSQPGDPLSLHEPIKIVITMSSTPNS-MTD
LESSLHLKVIGTDRADPQLDGEPATQGVASPPNS-EQRRIPVITLELSEDGR--GGAACP
ESNGSEKTPERLRVVEASSNQCSG--YESGEGGNATKDGSPAP-RDHCEATPLLTPSMVS
E-------STGGKEGQANLDPSSCKNSHEKRHNRVLSVDSGTDVFLSKNSAEITSD-KEK
TIPTSKSDLEAKEGQIPNESNFLEFVSLLESINTSKVVATHQSNGSAEQHKESRLLK---
-------DNCSQEKKEEILESEKPRGHN-----SRQGKPDVQCQDHPNNSPVFTEPAKIT
TLFQGSRQRQIIYRVTSQQDSSVLQVISGPETSVQDEISVDAMHIFIDEH-XXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXDIQISSSSTTTSESQDPSSGDPAVSALQQQLLLMVAR
RTQSDTPR-----------HLSQELEDSSCSSTQGKFNREQFYKLIIFPGKWIKVWYDRL
TLLALLD---RTEDVKENVLSVLLIVLVSLLGFLTLNQGFCKDMWTLLFCLVMASCQYSL
LK-----------SVQPDPASPIHGHNQIITYSRPIYFCLLCGLILLLDTGAKARHPPTY
VVYGLQLFSPGSLQSTRDHLIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXX--XXXXXXXXXXXXXXXXXXXXXX-EPWSTQHIPALFSAFCG-LLVALSYHLS
RQSSDPTVLXXXXXXXXXXXXXX-XXX---XXXXXXXXXXXXX--------XXXKDALQS
DLIVCSVFAVLSFAVSASTVFLSLRPFLSIVLFVLAGAVGFLA-HYLLPQLRKHHPWMWI
SHPILKNQEYQQREVTDIAHLMWFERLYVWLQYFEKYILYPAIILNALTIDAFAISNYRR
LGTHWDIFLMIV--AGMKLLRTSFCDPV--HQFVTLSFTVIFFHFDYKDISESFLLDFFM
MSIVFSK--LGDLLHKLQFIMTYVAPWQMAWGSSFHVFAQLFAIPHSA--------LLFF
QTIATSVFSTPLSPFLGSVIFIMSYVRPVKFWEKNYXXXXXXXXXXXXXXXXXXXXXXXX
XX-XXXXXX---XXXXX--XXXXXXXXXXXXXXXXXXXXGDFIASDYLNAV--HIEIGNG
LVT-QLRGLEFR-GTYCQQREVEAIMEGDEEDGGCCCCKPGHLPHLLSCNAAFNLRWLTW
EITRTQYILEGYSIVDNNAATMLQVFDLRRLLIRYYIKSIIYYMVTSPKLLSWIKNE-LL
KSLQPF-KWHYIERDLAMFNINTDDDYVPCLQGITRASFCNVYLEWIQYCARKQQ

PF05041 // ENSGT00390000013164_1_Domain_0 (1856, 2098)

EXXX-
XXXXXXXXXXXXXX---XXXXXXXXXXXXXXXXXXXXXLDSFLYGLHALFKGDFRITARD
EWVFADMDLLHRVVAPAVR-----MSLKLHQDQFTCPDEYEDPVVLYEAIQSFDS-KVVI
CHEGDPAWRTAVLSNKEELLTLRHVVDEGADEYKVIMLHKGFLSFKVIKVNKECVRGLWA
GQQQELIFLRNRNPERGSIQNNTQVLRNLINSSCDQPLGYPMYVSPLTTSYLGTHRQLKD
IWGGPVSLDGIRTWFRTKWLRMRKDCHAG-QHSGGNIEDVDGGGAPSMDH------GTSG
ESQESSAEPPRKDRCR--------DGVPRTG----RRKGRSQSVQACEALGQRPPIPSLS
GPVLDSHPPFIKTSTSVHELAPRLSSSQLSLHNSAASLHSQPPPATTTGH-LSVRERAEA
LLRSSLGSSTSSTLSFLFGKRSFSSALVISGLSAAEGGNTSDTQSSSSVNIVMGPSARAS
GQATRHLSE-PCEPTDVT-EQGQLSDGRLAEAMAA-NLGVTCRR-ASQEDMGLDDTASQQ
SASDEQ

------------------------------------------------------------
-------------------------MASQVLQLLR-------QGVWAALTGGWYHDPEHS
KFTNSC--H-------LYLWLFLL-------LLP--------LALHLAFPPNVL----TA
LFYCGSVTIFFAVIKLISYRLHLMFDKGEAIQHRSPRKRSKQKPEGEAS--SQHTARHKN
PS--NNRQIHSTKKEEPRGSLATPPLCCSSRGQSVHSQHSSG-PLELPAQETVEDLKGVV
LSEDQPEAL-VSSTSPGMKSESLPASQGRTPEPAPRPACPVKPVTTELFTARKGKESGG-
TAQ-RPARHRSESG-LVNPGALKKLPQLSLSQYDLLETDISFQPWGSEHSVLL-PQ-PKC
TQGPTRAQPQTRSPQDSLSSS-CCQCNTVLAKPT-E-EELT-------------------
---RTCGQVEMPLNQEVVDSDGEVAVTLIDTSQPGEPLSLHEPIKIVITMSSTQNS-ISD
LESSLHLRVTSSDRTSVRPSAESAGSGGAGPADL-EQVRIPLITLELTEDGG-GRGVSCS
EGNGGERTPERME-VM-SPEHCS----GSGPGD-----GSPI----PGSTLATLTPRVDP
E-------SEGSREGQANLDPASCKSSHEKRHARVLSVDSGTDVFLSRSTKEVVSD-GEK
PIPTSKSDLEAKEGQIPNESNFLEFVSLLESISTSKVVAPDF---PAEQKGASQGPE---
-------GHASPGTKEEAVENEKPNGRD-----PKPGKPDLPSQDPANGSPVFTQPSKSA
ALFQGSRQRHIIYRVTSQQDSSVLQVISGPETSVQEEMSLDAMHVFIDEH-GEVRSCYLK
SGDQKEGSSQHPPLNPDCVSHAREILLSSSSTTTTGSPDPSSGDPAVSALQQQLLLMVAR
RTQSETPRH-----------ISQDLEDSSRSSAQGKFNREQFYKFIIFPGKWIKVWYDRL
TLLALLD---RTEDVKENMVAVLLSVLVSLLGFLTLNRGFCRDLWVLLFCLVMASCQYSL
LK-----------SVQPDPASPIHGHNQIIAYSRPIYFCLLCSLILLLDAGAKARHPPSY
VVYGLKLFTPDTLQAVRDHLIVFLCCFPAISLLGLFPQINTFCTYLLEQIDMLLFGGSAV
SGITSAV--YSVGRSVLAAALLHAFCFSAVK-EPWSTQHIPALFSAFCG-LLVALSFHLS
RQSSDPSVL-LSFIQCKLLPKCLHQNL---EESATDPLPQRMK--------ESVKDVLRS
DLVICSAAAVLSFAVSASTVFLSLRPFLSIVLFALAGTVGLIT-HHLLPQLRKHHPWMWI
SHPVLRSKEYQQREARDIAHLMWFERLYVWLQCFEKYLLYPAIVLNALTLDAFSISNYRR
LGTHWDIFLMIT--AGMKLLRTSFCNPV--HQFANLGFTVIFFHFDYKDISESFLLDFFM
VSIVFTK--LGDLLQKLQFVLAYVAPWQMAWGSSFHVFAQLFAIPH--------SAMLFF
QTFATSIFSTPLSPFLGSVIFITSYVRPVKFWERSYNTR---RMDNSNTRLAVQMERDPG
SD-DNNLNSIFYEHLTRTLQESLCGDLVLGRWGNYSSGDCFILASDDLNAFVHLIEIGNG
LVTFQLRGLEFR-GTYCQQREVEAIMEGDEDDRGCCCCKPGHLPHLLSCNAAFHLRWLTW
EITRTQYILEGYSIIDNNAATMLQVYDLRRVLIRYYVKSIIYYMVTSPKLISWVKNESLL
KSLQPFAKWHHIERDLAMFNINIDDDYVPCLQGITRASYCNVFLEWIQYCAGKRQELSK-
TLEHV

PF05041 // ENSGT00390000013164_1_Domain_0 (1866, 2097)

DSDEDSALVTLAFALCILGRRALGTAAHNMAMSLDSFLYGLHALFKGDFRVTARD
EWVFADMDLLHKVVVPAIR-----MSLKLHQDQFTCPDEYEDPAVLYEAIRSFEK-KVVI
CHEGDPAWRGAVLSNKEELLTLRHVVDEGADEYKVIMLHRGFLSFKVIKVNKECVRGLWA
GQQQELIFLRNRNPERGSIQNNKQVLRNLINSSCDQPLGYPMYVSPLTTSYLGTHKQLQS
VWGGPVTLNRVRTWFQTRWLRMRKDCSVGQRSGGGNIEDG-EGGAVP---SAGGGSAPNG
ESRDGSTEQPRKGGTQQWASPR--GEAQRAG----RRKGRSQSVQAHSAISQRPPTLSSS
GPILESHQAFLQTSTSVHELAQRPSGSRLSLHTSAASLHSQPPPVTTTGH-LSVRERAEA
LIRSSLGSSTSSTLSFLFGKRSFSSALVISGLSAAEGGNTSDTQSSSSVNIVMGPSARAA
GHAARHFSE-PCEPTDSP-EQGQLQDGRLAEPVEE-NLGVLCRR-ASQEDMGLDDTASQQ
STSDEQ