Query Results 

----------MASEVVCGLIFRLLLPICLAVACAFRYNGLSFVYLIYLLLIPLFSEPTKT
T------MQGHTGRLLKSLCFTSLSFLLLHIIFHIT-----LASLEAQHRIAPGYNCSTW
EKTFRQIGF--EGNLKGADAGNGIRVFVPDIGMFIASLTIWLLCRNIVQKPVTDEAAQCN
LEFENEELAEGEKIDSEEALIYE-EDLDGGDGVEGELEESTKLKMFRRLAFVASKLKEFI
GNMITTAGKVVVTILLGS-SGMMLPSLTSSVYFFVFLGLCTWWSWCRTFDPLLFSCLCVL
LAIFTAGHLIGLYLYQFQFFQEAVPPNDYYA-RLFGIKSVIQTDCSSTWKIIVNPDLSWY
HHANPILLLVMYYTLATLI-RIWLQEPL--VQDERTK------EEDRALACSPIQI-TAE
RRRSLWYATHYPTDERKLLSMTQDDYKPSDGLLVTVNGNPVDYHTIHPTLPMENGPGKAD
LYSTPQYRWEPSDESSGRKE--EEEEKEEFEEERSREEKRSIKVHAMVSVFQFIMKQSYI
CALIAMM-AWSITYHSWLTFVLLIWSCTLWMIRNRRKYAMISSPFMVVYGNLLLILQYIW
SFELP--EIKKVPGFLEKKEPGELAS---------KILFTITFWLLLRQHLTEQKALQEK
EALLSEVKIGSQENEEK-----DEELQDIQV---EGESKEK-------------------
-----EEEEEVKEEKQERKKAEEEE---VEEEDEQDIMKVLGNLVVAMFIKYWIYVCGGM
FFFVSFEGKIVMYKIIYMVLFLFCVALYQVHYEWWRKILKYFWMSVVIYTMLVLIFIYTY
QFENFPGLWQNMTGLKKEKLEDLGLKQFTVAELFTRIFIPTSFLLVCILHLHYFHDRFLE
LTDLKSIPSKEDNTIYR-------------------------LAHPEGSLPDLTMMHLTA
SLEKPEVRKLAEPGEEKPEGYSEKAQ--KGELGKDSEESEEDGE-EE-----EESEE-EE
ETSDLRNKWHLVIDRLTVLFLKFLEYFHKLQVFMWWILELHIIKIVSSYIIWVSVKE--V
SLFNYVFLISWAFALPYAKLRRLASSVCTVWTCVIIVCKMLYQLQTIKPENFSVNCSLPN
ENQTNIP-LNELNKSLLYSAP-VDPTEWVGLRKSSPLLVYLRNNLLMLAILAFEVTIYRH
QEYYRGRNNLTAPVSKTIFHDITRLHLDDGLVNCAKYFINYFFYKFGLETCFLLSVNVIG
QRMDFYAMIHACWLIAVLYRRRRKAIAEIWPKYCCFLACIITFQYFICIGIPPAPCRDYP
WRFKGASFNDNIIKWLYFPDFIVRPNPVFLVYDFMLLLCASLQRQIFEDENKAAVRIMAG
DNVEICMNLDAASFSQHNPVPDFIHC-RSYLDMSKVIVFSYLFWFVLTIIFITGTTRISI
FCMGYLVACFYFLLFGGDLLLKPIKSILRYWDWLIAYNVFVITMKNILSIG

PF15917 // ENSGT00390000013029_1_Domain_0 (1492, 1775)

ACGYIGTLV
HNSCWLIQAFSLACTVKGYQ--------MPPANSPCTLPSGEAGIIWDSICFAFLLLQRR
VFMSYYFLHVVA--------DIKASQILASRGAELFQATIVKAVKARIEEEKKSMDQLKR
QMDRIKARQQKYKKGKERMLSLTQEPGEGQDIQKLSEEDDE-READKQKAKGKKKQWWRP
WVDHASMVRSGDYYLFETDSEEEEEEELKKEDEEPPRRSAF-------------------
--------------QFVYQAWITDPKTALRQRNK

ENSGT00390000013029_1_Linker_0_3 (1775, 2665)

EKKSSAREERKRRRKGSKEGP--VEW
EDREDEPIKKKSDGPDNIIKRIFNILKFTWVLFLATVDSFTTWLNSISREHIDISTVLRI
ERCMLTREIKKGN-VPTRESI-HMYYQNHI-MNLSRESGLDTIDEHPGAASGAQTAHRMD
SLD---SHDSIS------------------------------------------------
--------SEPTQCTMLYSRQGTTETIEEVEAEQEEEAGSTVPESGKTKEYE--------
-------AAGYDVGAVGAEEVSLTPD---EELTQFSTLDGDVEAPPSYSKAVSFEHLSFG
SQDD-STGKNHMAVSPDDSRTD-----KLGSSILPPLTHELTASELLLNKMFHDDE--LE
ESEKFYVGQPRFLLLFYAMYNTLVARSEMVCYFVIILNHMVSASMITLLLPILIFLWAML
SVPRPSRRFWMMAIVYTEVAIVVKYFFQFGFFPWNKTAEL--NKDKPYHPPNIIGVEKKE
GYVLYDLIQLLALFFHRS--ILKCHGLWDEDDITESGMDKEESDDEL---SLSHGRRDSS
---DSLKSINLAASVES-----------------VHVTFPEQPTAVRRKH--SSTGSEPS
QRSSFSSNRSQR-----GST-STRNSSQKG--SSVLSIK-----QKSKRELY-MEKFQEH
LIKAKAF----------------TIKKTLQIYVPIKQFFYNLIHPDYSAVTDVYVLMFLA
DTVDFIIIVFGFWAFGK-HSAAADITSSLSEDQVPGPFLVMVLIQFGTMVVDRALYLRKT
VLGKVIFQVILVFGIHFWMFFILPGVTERKFSQNLVAQLWYFVKCVYFGLSAYQIRCGYP
TRVLGNFLTKSYNYVNLFLFQGFR

PF12166 // ENSGT00390000013029_1_Domain_3 (2665, 3094)

LVPFLTELRAVMDWVWTDTTLSLSSWICVEDIYAHI
FILKCWRESEKRYPQPRGQKKKKVVKYGMGGMIIVLLICIVWFPLLFMSLIKSVAGVINQ
PLDVSVTITLGGYQPIFTMSAQQSQLKVMDQQNFNKFIQA-----FSRDTGAMQFLENYE
KEDITVAELEGNSNSLWTISPPSKEKMIHELLDPNSSFSVVFSWSIQRNLSLGAKAEIAT
DKLSFTLQNSTRKNIAKMIAGNNTESSKTPVTIEKIYPYYVKAPSDSNSKPIKQLLS--E
NNFMDITI-------------ILSRDNTTKYNSEWWVLNLTGNRIYNPESQALELVVFND
KVSPPSLGFLAGYGIMGLYASVVLVIGKFVREFFSGISHSIMFEELPNVDRILKLCTDIF
LVRETGELELEEDLYAKLIFLYRSPETMIKWTREKTN

----------MASEVVCGLIFRLLLPICLAVACAFRYNGLSFVYLIYLLLIPLFSEPTKT
T------MQGHTGRLLKSLCFTSLSFLLLHIIFHIT-----LASLEAQHRIAPGYNCSTW
EKTFRQIGF--ES-LKGADAGNGIRVFVPDIGMFIASLTIWLLCRNIVQKPMTDEAAQCN
LEFENEELAEGEKIDSEEALIYE-EDLDGGDGVEGELEESTKLKMFRRFASVASKLKEFI
GNMITTAGKVVVTILLGS-SGMMLPSLTSSVYFFVFLGLCTWWSWCRTFDPLLFSCLCVL
LAIFTAGHLIGLYLYQFQFFQEAVPPNDYYA-RLFGIKSVIQTDCSSTWKIIVNPDLSWY
HHANPILLLVMYYTLATLI-RIWLQEPL--VQDERTK------EEDRALACSPIQI-TAE
RRRSLWYATHYPTDERKLLSMTQDDYKPSDGLLVTVNGNPVDYHTIHPTLPMENGPGKAD
LYSTPQYRWEPSDESSEKPEE-EEEEKEEFEEERSREEKRSIKVHAMVSVFQFIMKQSYI
CALIAMM-AWSITYHSWLTFVLLIWSCTLWMIRNRRKYAMISSPFMVVYGNLLLILQYIW
SFELP--EIKKVPGFLEKKEPGELAS---------KILFTITFWLLLRQHLTEQKALQEK
EAFLSEVKIGSQENEEK-----DEELQDLQV---EGEPKEK-------------------
-----EEEEKAKEEKQERKKAEEEE---VEEEDEQDIMKVLGNLVVAMFIKYWIYVCGGM
FFFVSFEGKIVMYKIIYMVLFLFCVALYQVHYEWWRKILKYFWMSVVIYTMLVLIFIYTY
QFENFPGLWQNMTGLKKEKLEDLGLKQFTVAELFTRIFIPTSFLLVCILHLHYFHDRFLE
LTDLKSIPSKEDNTIYSHAKVNGRVYLIINSIKKKLPIHQNELAHPEGSLPDLTMIHLTA
SLEKPEVRKLAEPGEEKPEGYSEKAQ--KGELGKDSEESEEDGE-EE-----EESEEEEE
ETSDLRNKWHLVIDRLTVLFLKFLEYFHKLQVFMWWILELHIIKIVSSYIIWVSVKE--V
SLFNYVFLISWAFALPYAKLRRLASSVCTVWTCVIIVCKMLYQLQTIKPENFSVNCSLPN
ENQTNIP-LNELNKSLLYSAP-IDPTEWVGLRKSLPLLVYLRNNLLMLAILAFEVTIYRH
QEYYRGRNNLTAPVSKTIFHDITRLHLDDGLVNCAKYFINYFFYKFGLETCFLLSVNVIG
QRMDFYAMIHACWLIAVLYRRRRKAIAEIWPKYCCFLACIITFQYFICIGIPPAPCRDYP
WRFKGASFNDNIIKWLYFPDFIVRPNPVFLVYDFMLLLCASLQRQIFEDENKAAVRIMAG
DNVEICMNLDAASFSQHNPVPDFIHC-RSYLDMSKVIVFSYLFWFVLTIIFITGTTRISI
FCMGYLVACFYFLLFGGDLLLKPIKSILRYWDWLIAYNVFVITMKNILSIG

PF15917 // ENSGT00390000013029_1_Domain_0 (1492, 1775)

ACGYIGTLV
HNSCWLIQAFSLACTVKGYQ--------MPPANSPCTLPSGEAGIIWDSICFAFLLLQRR
VFMSYYFLHVVA--------DIKASQILASRGAELFQATIVKAVKARIEEEKKSMDQLKR
QMDRIKARQQKYKKGKERMLSLTQEPGEGQDIQKLSEEDDE-READKQKAKGKKKQWWRP
WVDHASMVRSGDYYLFETDSEEEEEEELKKEDEEPPRRSAF-------------------
--------------QFVYQAWITDPKTALRQRHK

ENSGT00390000013029_1_Linker_0_3 (1775, 2665)

EKKRSAREERKRRRKGSKEGP--VVW
EEREDEPVKKKSDGPDNIIKRIFNILKFTWVLFLATVDSFTTWLNSISREHIDISTVLRI
ERCMLTREIKKGN-VPTRESI-HMYYQNHI-MNLSRESGLDTIDEHPGAASGAQTAHRMD
SLD---SHDSIS------------------------------------------------
--------SEPTQCTMLYSRQGTTETIEEVEAEQEEEAGSTVPESREAKEFE--------
-------AAGFDVGAMGAEEVSLTPE---EELTQFSTLDGDVEAPPSYSKAVSFEHLSFG
SQDD-STGKNHMAVSPDDSRTD-----KLGSSILPPLTHELTASELLLNKMFHDDE--LE
ESEKFYVGQPRFLLLFYAMYNTLVARSEMVCYFVIILNHMVSASMITLLLPILIFLWAML
SVPRPSRRFWMMAIVYTEVAIVVKYFFQFGFFPWNKTAEL--NKDKPYHPPNIIGVEKKE
GYVLYDLIQLLALFFHRS--ILKCHGLWDEDDMTESGMDKEESDDEL---SLSHGRRDSS
---DSLKSINLAASVES-----------------VHVTFPEQQTAVRRKR--SSTSSEPS
QRSSFSSNRSQR-----GST-STRNSSQKG--SSVLSIK-----QKSKRELY-MEKLQEH
LIKAKAF----------------TIKKTLQIYVPIKQFFYNLIHPDYSAVTDVYVLMFLA
DTVDFIIIVFGFWAFGK-HSAAADITSSLSEDQVPGPFLVMVLIQFGTMVVDRALYLRKT
VLGKVIFQVILVFGIHFWMFFILPGVTERKFSQNLVAQLWYFVKCVYFGLSAYQIRCGYP
TRVLGNFLTKSYNYVNLFLFQGFR

PF12166 // ENSGT00390000013029_1_Domain_3 (2665, 3094)

LVPFLTELRAVMDWVWTDTTLSLSSWICVEDIYAHI
FILKCWRESEKRYPQPRGQKKKKVVKYGMGGMIIVLLICIVWFPLLFMSLIKSVAGVINQ
PLDVSVTITLGGYQPIFTMSAQQSQLKVMDQQNFDKFIRA-----FSRDTSAMQFLENYE
KEDITVAELEGNSNSLWTISPPSKEKMIHELLDPNSSFSVVFSWSIQRNLSLGAKAEIAT
DKLSFTLQNSTRKNIAKMIAGNNTESSKTPVTIEKIYPYYVKAPSDSNSKPIKQLLS--E
NNFMDITI-------------ILSRDNTTKYNSEWWVLNLTGNRIYNPESQALELVVFND
KVSPPSLGFLAGYGIMGLYASVVLVIGKFVREFFSGISHSIMFEELPNVDRILKLCTDIF
LVRETGELELEEDLYAKLIFLYRSPETMIKWTREKTN

----------MASEVVCGLIFRLLLPICLAVACAFRYNGLSFVYLIYLLLIPLFSEPTKT
T------MQGHTGRLLKSLCFISLSFLLLHIIFHIT-----LASLEAQHRIAPGYNCSTW
EK---TFRQIGFESLKGADAGNGIRVFVPDIGMFIASLTIWLLCRNIVQKPVTDEAAQSN
LEFENEELAGGEKIDSEEALIYE-EDLDGGDGVEGELEESTRLKMFRRLACVASKLKEFI
GNMITTAGKVVVTILLGS-SGMMLPSLTSSVYFFVFLGLCTWWSWCRTFDPLLFSCLCVL
LAIFTAGHLIGLYLYQFQFFQEAVPPSDYYA-RLFGIKSVIQTDCSSTWKIIVNPDLSWY
HHANPILLLVMYYTLATLI-RIWLQEPL--VQEERTK------EEDKALACSPIQI-TAE
RRRSLWYATHYPTDERKLLSMTQDDYKPSDGLLVTVNGNPVDYHTIHPSLPMENGPGKAD
LYSTPQYRWEPSDESSEKREE-EEEEKEEFEEERSREEKRSIKVHAMVSVFQFIMKQSYI
CALIAMM-AWSITYHSWLTFVLLIWSCTLWMIRNRRKYAMISSPFMVVYGNLLLILQYIW
SFELP--EIKKVPGFLEKKEPGELAS---------KILFTITFWLLLRQHLTEQKALREK
EALLSEVKIGSQENEEK-----DEELQDIQV---EGEPKEK-------------------
-----EEEEEAKEEKQERKKVEEEE---VEEEDEQDIMKVLGNLVVAMFIKYWIYVCGGM
FFFVSFEGKIVMYKIIYMVLFLFCVALYQVHYEWWRKILKYFWMSVVIYTMLVLIFIYTY
QFENFPGLWQNMTGLKKEKLEDLGLKQFTVAELFTRIFIPTSFLLVCILHLHYFHDRFLE
LTDLKSIPSKEDNTIYSHAKVNGRVYLIINSIKKKLPIHQNELAHPEGSLPDLTMMHLTA
KLEKPEVRKLAEPGEEKPEGYSEKAQ--KGDLGKDSEESEEDGE-EE-----EESEE-EE
ETSDLRNKWHLVIDRLTVLFLKFLEYFHKLQVFMWWILELHIIKIVSSYIIWVSVKE--V
SLFNYVFLISWAFALPYAKLRRLASSVCTVWTCVIIVCKMLYQLQTIKPENFSVNCSLPN
ENQTNIP-LNELNKSLLYSAP-VDPTEWVGLRKSSPLLVYLRNNLLMLAILAFEVTIYRH
QEYYRGRNNLTAPVSKTIFHDITRLHLDDGLINCAKYFINYFFYKFGLETCFLMSVNVIG
QRMDFYAMIHACWLIAVLYRRRRKAIAEIWPKYCCFLACIITFQYFICIGIPPAPCRDYP
WRFKGASFNDNIIKWLYFPDFIVRPNPVFLVYDFMLLLCASLQRQIFEDENKAAVRIMAG
DNVEICMNLDAASFSQHNPVPDFIHC-RSYLDMSKVIVFSYLFWFVLTIIFITGTTRISI
FCMGYLVACFYFLLFGGDLLLKPIKSILRYWDWLIAYNVFVITMKNILSIG

PF15917 // ENSGT00390000013029_1_Domain_0 (1492, 1775)

ACGYIGTLV
HNSCWLIQAFSLACTVKGYQ--------MPAANSPCTLPSGEAGIIWDSICFAFLLLQRR
VFMSYYFLHVVA--------DIKASQILASRGAELFQATIVKAVKARIEEEKKSMDQLKR
QMDRIKARQQKYKKGKERMLSLTQEPGEGQDMQKLSEEDDE-READKQKAKGKKKQWWRP
WVDHASMVRSGDYYLFETDSEEEEEEELKKEDEEPPRRSAF-------------------
--------------QFVYQAWITDPKTALRQRHK

ENSGT00390000013029_1_Linker_0_3 (1775, 2665)

EKKRSAREERKRRRKGSKEGP--VEW
EDREDEPIKKKSDGPDNIIKRIFNILKFTWVLFLATVDSFTTWLNSISREHIDISTVLRI
ERCMLTREIKKGN-VPTRESI-HMYYQNHI-MNLSRESGLDTIDERPGAASGAQTAHRMD
SLE---SHDSIS------------------------------------------------
--------SEPTQCTMLYSRQGTTETIEEVEAEQEEEAGSTVPEPREAKEYE--------
-------AAGYDVGAVGAEEASLTPE---EELTQFSTLDGDVEAPPSYSKAVSFEHLSFG
SQDD-SAGKNHMAVSPDDSRTD-----KLGSSILPPLTHELTASELLLNKMFHDDE--LE
ESEKFYVGQPRFLLLFYAMYNTLVARSEMVCYFVIILNHMVSASMITLLLPILIFLWAML
SVPRPSRRFWMMAIVYTEVAIVVKYFFQFGFFPWNKNAEV--NKDKPYHPPNIIGVEKKE
GYVLYDLIQLLALFFHRS--ILKCHGLWDEDDMTESGMDKEESDDEL---SLGHGRRDSS
---DSLKSINLAASVES-----------------VHVTFPEQQTAVRRKR--SSSNSEPS
QRSSFSSNRSQR-----GST-STRNSSQKG--SSVLSIK-----QKSKRELY-MEKLQEH
LIKAKAF----------------TIKKTLQIYVPIKQFFYNLIHPDYSAVTDVYVLMFLA
DTVDFIIIVFGFWAFGK-HSAAADITSSLSEDQVPGPFLVMVLIQFGTMVVDRALYLRKT
VLGKVIFQVILVFGIHFWMFFILPGVTERKFSQNLVAQLWYFVKCVYFGLSAYQIRCGYP
TRVLGNFLTKSYNYVNLFLFQGFR

PF12166 // ENSGT00390000013029_1_Domain_3 (2665, 3094)

LVPFLTELRAVMDWVWTDTTLSLSSWICVEDIYAHI
FILKCWRESEKRYPQPRGQKKKKVVKYGMGGMIIVLLICIVWFPLLFMSLIKSVAGVINQ
PLDVSVTITLGGYQPIFTMSAQQSQLKVMDQQNFNKFIQA-----FSRDTGAMQFLENYE
KEDITVAELEGNSNSLWTISPPSKQKMIHELLDPNSSFSVVCSWSIQRNLSLGAKSEIAT
DKLSFPLKNITRKNIAKMIAGNSTESSKTPVTIEKIYPYYVKAPSDSNSKPIKQLLS--E
NNFMDITI-------------ILSRDNTTKFNSEWWVLNLTGNRIYNPNSQALELVVFND
KVSPPSLGFLAGYGIMGLYASVVLVIGKFVREFFSGISHSIMFEELPNVDRILKLCTDIF
LVRETGELELEEDLYAKLIFLYRSPETMIKWTREKTN

----------MASEVVCGLVFRLLLPICLAVACAFRYNGLSFVYLIYLLLIPLFSEPTKA
T------MQGHTGRLLKSLCFTSLSFLLLHIIFHIT-----LASLEAQHRIAPGYNCSTW
EKTFRQIGFE---SLKGADAGNGIRVFVPDVGMFIASLTIWLVCRNIVQKPVAEEAAQCN
PEFENEESAGGEKIDSEEALIYE-EDLDEGDGAEGDLEESTKLKLFRRLASVASKLKEFI
GNMITTAGKVVVTILLGS-SGMMLPSLTSSVYFFVFLGLCTWWSWCRTFDPLLFSCLCVL
LAIFTAGHLIGLYLYQFQFFQEAVPPNDYYA-RLFGIKSVIQTDCSSTWKIIANPDLSWY
HHANPIVLLVMYYTLATLI-RIWLQEPV--VQEEKTKE------EDRALACSPAPI-TAE
RRRSLWYATHYPTDERKLLSMTQDDYKPSDGLLVTVNGNPVDYHTIHPSLPLENGPAKAD
LYSTPQYRWEPEED---------NDEKEEFEEERSREEKRSVKVHAMVSVFQFIMKQSYI
CALIAMM-AWSITYHSWLTFVLLIWSCTLWMIRNRRKYAMISSPFMVVYGNLLLILQYIW
SFELP--EIKKVPGFLEKKEPGELAS---------KILFTITFWLLLRQHLTEQKALQEK
EALLSEVKIGSQENEEK----DDE--QDVQVD---SEAQEKEEGEEPKEEQQE-------
-------------------RR---EDEDEEEADEQDVMKVLGNLVVALFIKYWIYVCGGM
FFFVSFEGKIVMYKIIYMVLFLFCVALYQVHYEWWRRILKYFWMSVVIYTMLVLIFIYTY
QFENFPGLWQNMTGLKKEKLEDLGLKQFTVAELFTRIFIPTSFLLVCILHLHYFHDRFLE
LTDLKSIPSKEDSAVYSSARPSCPLTENLD-----------LLAHPEGSLPDLAMMKLTA
SLEVAEVKQLAGPGEEMPGGCPAKAKK--GEP--GRDSEDEDEDEDEE-------DEEEE
ETSDLRNKWHLVIDRLTVLLLRFLEGFHQLQTFLWWILELHIVKIVSSYIIWVSVKE--V
SLFNYVFLISWAFALPYAKLRRLASSVCTVWTCVIIVCKMLYQLQTIKPENFSVNCSLPN
ENQTNIP-LHQLNKSLLYSAP-IDPTEWVGLRKSSPLLVYLRNNLLMLAILAFEVTIYRH
QEYYRGRNNLSTPVSKTIFHNITRLQLDDGLVNCAKYFINYFFYKFGLETCFLMSVNVIG
QRMDFYAMIHACWLIAVLYRRRRKAIAEIWPKYCCFLACIITFQYFICIGIPPAPCRDYP
WRFKGASFNDNIVKWLYFPDFIVRPNPVFLVYDFMLLLCASLQRQIFEDENKAAVRIVAG
DNVEICMNLDAASFSQHNPVPDFIHC-RSYLDMSKVVIFSYLFWFVLTIIFITGTTRISI
FCMGYLVACFYFLLFGGDLLLKPIKSILRYWDWLIAYNVFVITMKNILSIG

PF15917 // ENSGT00390000013029_1_Domain_0 (1492, 1775)

ACGYIEKLV
QNSCWLIQAFSLACTVKGYKM--------PDDDSSCKLPSGEAGIIWDSICFAFLLLQRR
VFMSYYFLHVVA--------DVKASQILASRGAELFQATIVKAVKARIEEEKKSMDQLKR
QMDRIKARQQKYKKGKERMLSLTQESGEGQDLQKLSEEDDE-IRI---------------
--LFYLVVRSGDYYLFETDSEEEEEEELKKEDEEPPRRSAF-------------------
--------------QFVYQAWITDPKTALRQRRK

ENSGT00390000013029_1_Linker_0_3 (1775, 2665)

EKKRSAREEQKRRRKESGEGP--VEW
EDREDEPVKKKSDGPDNIIKRIFNILKFTWVLFLATVDSFTTWLNSISREHIDISTVLRI
ERCMLTREIKKGN-VPTRESI-HMYYQNHI-MNLSRESGLDTIDDHAGTTAGAETAHRMD
SLD---SHDSISSCYTEATMLFSRQSTLDDLDGPETVPKTSERARPGLRKMLSMDVSSSS
AESTSLGSSEPTQCTMLYSRQGTTETIEEVEAEQDEETSEGA------------------
---------------------------REAESPQDPTEDGDVEAPPSYSKAVSFERLSFD
-SRDDSAGQTHMEVSPDDS-----RSDRLEASILPPLTHELTASELLLNKMFHDDE--LE
ESEKFYVGQPRFLLLFYALYNTLVARSEMVCYFVIILNHMVSASMITLVLPILIFLWAML
SVPRPSRRFWMMAIVYTEVAIVVKYFFQFGFFPWNKNVEL--NKDKPYHPPNIIGVEKKD
AYVLYDLIQLLALFFHRS--ILKCHGLWDEDDIVDSGSDKVDSDDEL---SLGHGRRASS
---DSLKSINLAASVES-----------------VHVTFPEQPAAVRRKRS--SSGSQTS
QESSFSSNRSKR-----GIAARPEQGRA--------------------------------
-----------------SCAGGQQRAQTLQLYVPIRQFFYDLIHPDYSAVTDVYVLMFLA
DTVDFVIIVFGFWAFGK-HSAAADITSSLSEDQVPGPFLVMVLIQFGTMVVDRALYLRKT
VLGKVIFQVILVFGIHFWMFFILPGVTERKFSQNLVAQLWYFVKCVYFGLSAYQIRCGYP
TRVLGNFLTKSYNYVNLFLFQGFR

PF12166 // ENSGT00390000013029_1_Domain_3 (2665, 3094)

LVPFLTELRAVMDWVWTDTTLSLSSWICVEDIYAHI
FILKCWRESEKRYPQPRGQKKKKVVKYGMGGMIIVLLICIVWFPLLFMSLVKSVAGVINQ
PLDVSVTITLGGYQPIFTMSAQQSQLKVMDQPMFNKFIK-----------GAMQFLENYE
KEDITVAELEGNSNSLWTISPPSKQKMIHELKDPNSSFSVVFSWSIQRNMSLGAKAEIAT
DKLSFPLKNKTRENIAKMIAGGDTESSRTPVTIERIYPYYVKAPSDSNSKPIKQLLS--E
NNFMNITI-------------ILSRDNATNSNSEWWVLNLTGNRIYNQEAQALELVVFND
KVSPPSLGFLAGYGIMGLYASVVLVIGKFVREFFSGISHSIMFEELPNVDRILKLCTDIF
LVRETGELELEEDLYAKLIFLYRSPETMIKWTREKTN

------------------------------------------------------------
------------------------------------------------------------
-------------SLKGADAGNGIRVFVPDIGMFIASLTIWLVCRTIVKKPDTEEVAQFN
SECENEELAGGEKMDSEEALIYE-EDLDGEEGMEGELEESTKLKMFRRLASVASKLKEFI
GNMITTAGKVVVTILLGS-SGMMLPSLTSAVYFFVFLGLCTWWSWCRTFDPLLFGCLCVL
LAIFTAGHLIGLYLYQFQFFQEAVPPNDYYA-RLFGIKSVIQTDCSSTWKIIVNPDLSWY
HHANPILLLVMYYTLATLI-RIWLQEPL--VQEEMSK------EEEGALDGCSNQN-TAE
RRRSLWYATQYPTDERKLLSMTQDDYKPSDGLLVTVNGNPVDYHTIHPSLPIENGPAKTD
LYTTPQYRWEPSEESSEKKEE-EEDKREDSEGEGSQEEKRSVRIHAMVAVFQFIMKQSYI
CALIAMM-AWSITYHSWLTFVLLIWSCTLWMIRNRRKYAMISSPFMVVYANLLLVLQYIW
SFELP--EIKKVPGFLEKKEPGELAS---------KILFTITFWLLLRQHLTEQKALQEK
EALLSEVKIGSQELDEKVFCFEDEELQDIQV---EGEPIE--------------------
--KEE-EEEEIKE---DRHEVKKEEEEEEEDDDDQDIMKVLGNLVVALFIKYWIYVCGGM
FFFVSFEGKIVMYKIIYMVLFLFCVALYQVHYEWWRKILKYFWMSVVIYTMLVLIFIYTY
QFENFPGLWQNMTGLKKEKLEDLGLKQFTVAELFTRIFIPTSFLLVCILHLHYFHDRFLE
LTDLKSIPSKEDNTIYSHAKVNGRVYLIIN-----------RLAHPEGSLPDLAIMNMTA
SLDKPERQKLAEPGEERTEECAKKAE--KGEAGKDSDESEEEEG-EE-------EESEEE
ESSDLRNKWHLVIDRLTVLFLKFLEYFHKLQVFMWWILELHIIKIVSSYIIWVTVKEAMV
SLFNYVFLISWAFALPYAKLRRVASSVCTVWTCVIIVCKMLYQLQTIKPENFSVNCSLPN
ENQTNIP-LNELNKSLLYSAP-VDPTEWVGLRKSSPLLVYLRNNLLMLAILAFEVTVYRH
QEYYRGRNNLTAPVSKTIFHDITRLHLDDGLINCAKYFVNYFFYKFGLETCFLMSVNVIG
QRMDFYAMIHACWLIGVLYRRRRKAIAEVWPKYCCFLACIITFQYFVCIGIPPAPCRDYP
WRFKGANFNDNIIKWLYFPDFIVRPNPVFLVYDFMLLLCASLQRQIFEDENKAAVRIMAG
DNVEICMNLDAASFSQHNPVPDFIHC-RSYLDMSKVIIFSYLFWFVLTIIFITGTTRISI
FCMGYLVACFYFLLFGGDLLLKPIKSILRYWDWLIAYNVFVITMKNILSIG

PF15917 // ENSGT00390000013029_1_Domain_0 (1492, 1774)

ACGYIGALV
RNSCWLIQAFSLACTVKGYK--------MPEDDSRCKLPSGEAGIIWDSICFAFLLLQRR
VFMSYYFLHVVA--------DIKASQILASRGAELFQATIVKAVKARIEEEKKSMDQLKR
QMDRIKARQQKYKKGKERMLSLTQESGEGQDIQKVSEEDDE-READKQKAKGKKKQWWRP
WVDHASMVRSGDYYLFETDSEEEEEEELKKEDEEPPRKSAF-------------------
--------------QFVYQAWITDPKTALRQRR

ENSGT00390000013029_1_Linker_0_3 (1774, 2665)

KEKKKMAREEQKGRRKGSGEGP--VEW
EDREDEPIKKKSDGPDNIIKRIFNILKFTWVLFLATVDSFTTWLNSISREHIDISTVLRI
ERCMLTREIKKGN-VPTRESI-HMYYQNHM-MNLSRESGLDTIDEHSGAGSRAQAAHRMD
SLD---SHDSISSCYTEATLLISRQSTLDDLDGQDPVPKTSERARPRLRKVFSMDMSSSS
ADSGSVASSEPTQCTMLYSRQGTTETIEEVEAEAEEEVVESLEPELHDAEEK--------
-----EYAAD---YEAGVEEVSLTPD---EELPQFSTDDGDVEAPPSYSKAVSFEHLSFA
SQDD-SGGKNHMVVSPDDSRTD-----KLESSILPPLTHELTASDLLMSKMFRDDE--LE
ESEKFYVDQPRFLLLFYAMYNTLVARSEMVCYFVIILNHMISASIITLLLPILIFLWAML
SVPRPSRRFWMMAIVYTEVAIVVKYFFQFGFFPWNKDLEI--YKDRPYFPPNIIGVEKKE
GYVLYDLIQLLALFFHRS--ILKCHGLWDEDDIVDSNTDKEGSDDEL---SLGQGRRGSS
---ESLKSINLAASVES-----------------VHVTFPEQPAAIRRKR--SCSSSQIS
PRSSFSSNRSKR-----GST-STRNSSQKG--SSVLSIK-----QKSKRELY-MEKLQEH
LIKAKAF----------------TIKKTLQIYVPIRQFFYDLIHPDYSAVTDVYVLMFLA
DTVDFIIIVFGFWAFGK-HSAAADITSSLSEDQVPGPFLVMVLIQFGTMVVDRALYLRKT
VLGKVIFQVILVFGIHFWMFFILPSVTERKFSQNLVAQLWYFVKCVYFGLSAYQIRCGYP
TRVLGNFLTKSYNYVNLFLFQGFR

PF12166 // ENSGT00390000013029_1_Domain_3 (2665, 3094)

LVPFLTELRAVMDWVWTDTTLSLSSWICVEDIYAHI
FILKCWRESEKRYPQPRGQKKKKAVKYGMGGMIIVLLICIVWFPLLFMSLIKSVAGVINQ
PLDVSVTITLGGYQPIFTMSAQQSQLKVMDGTKYNEFIKS-----FGPNSGAMQFLENYE
RQDITVAELEGNSNSLWTISPPSKQKMIQELTDPNSCFSVVFSWSIQRNMTLGAKAEIAT
DKLSFPLTDATRSSIAKMIAGNDTESSNTPVTIEKIYPYYVKAPSDSNSKPIKQLLS--E
NNFMNITI-------------ILFRDNVTKSNSEWWVLNLTGSRIFNQGSQALELVVFND
KVSPPSLGFLAGYGIMGLYASVVLVIGKFVREFFSGISHSIMFEELPNVDRILKLCTDIF
LVRETGELELEEDLYAKLIFLYRSPETMIKWTREKTN

------------------------------------------------------------
-------MQGHTGRLLKSLCFTSLSFLLLHIIFHIT-----LASLEAQHRIGPGYNCSTW
EKTFRQIGFE---SLKGADAGNGIRVFVPDIGMFIASLTIWLVCRNIVQKPVTEETAQYN
SEFENEESAGGEKLDPEEALIYE-EDLDEGDGVEGEVEDSTKLKMFRRLASVASKLKEFI
GNMITTAGKVVVTILLGS-SGMMLPSLTSSVYFFVFLGLCTWWSWCRTFDPLLFSCLCVL
LAIFTAGHLIGLYLYQFQFFQEAVPPNDYYA-RVFGVEGIHTTDFQLTWHLVGFPHVFLY
HHLSHLLLRFLAMTLFTLIRVIWLHEPV--VQDDRTKE------EDRALACSPIQI-TAE
RRRSLWYATHYPTDERKLLSMTQDDYKPSDGLLVTVNGNPVDYHTIHPSLPVENGPAKAD
LYSTPQYRWEPSEDSSEKKEE-EEDEKEEFEEERSHEEKRSVKVHAMVSVFQFIMKQSYI
CALIAMM-AWSITYHSWLTFVLLIWSCTLWMIRNRRKYAMISSPFMVVYGNLLLILQYIW
SFELP--EIKKVPGFLEKKEPGELAS---------KILFTITFWLLLRQHLTEQKALQEK
EALLSEVKIGSQENEEK-----DD-EQDIQME---GDAGEKEE-DEPKEEKQE-------
-------------------RR-KEE--EMEEDDDQDIMKVLGNLVVAMFIKYWIYVCGGM
FFFVSFEGKIVMYKIIYMVLFLFCVALYQVHYEWWRRILKYFWMSVVIYTMLVLIFIYTY
QFENFPGLWQNMTGLKKEKLEDLGLKQFTVAELFTRIFIPTSFLLVCILHLHYFHDRFLE
LTDLKSIPSKEDSAIYSHAKVNGRVYLIIN-----------RLAHPEGSLPDLAMMNLTA
SLDKPDLKKLAEPREDKPEGCPEKAGK--AEL--GKDSEEEEEEE--EEEEEEEEEEEEE
ETSDLRNKWHLVIDRLTVLFLKFLEYFHKLQVFMWWILELHIIKIVSSYIIWVSVKE--V
SLFNYVFLISWAFALPYAKLRRLASSVCTVWTCVIIVCKMLYQLQTIKPENFSVNCSLPN
ENQTNIP-INQLNKSQLYSAP-IDPTEWVGLRKSSPLLVYLRNNLLMLAILAFEVTIYRH
QEYYRGRNNLTAPVSKTIFHDITRLHLDDGLINCAKYFINYFFYKFGLETCFLMSVNVIG
QRMDFYAMIHACWLIAVLYRRRRKAIAEIWPKYCCFLACIITFQYFICIGIPPAPCRDYP
WRFKGASFNDNIIKWLYFPDFIVRPNPVFLVYDFMLLLCASLQRQIFEDENKAAVRIMAG
DNVEICMNLDAASFSQHNPVPDFIHC-RSYLDMSKVIIFSYLFWFVLTIIFITGTTRISI
FCMGYLVACFYFLLFGGDLLLKPIKSILRYWDWLIAYNVFVITMKNILSIGACGYIEKLV
QNSCWLIQAFSLACTVKGYKM--------PDDDSSCKLPSGEAGIIWDSICFAFLLLQRR
VFMSYYFLHVVA--------DIKASQILASRGAELFQATIVKAVKARIEEEKKSMDQLKR
QMDRIKARQQKYKKGKERMLSLTQESGEGQDIQKLSEEDDE-READKQKAKGKKKQWWRP
WVDHASMVRSGDYYLFETDSEEEEEEELKKEDEEPPRRSAF-------------------
--------------QFVYQAWITDPKTALRQRRKEKKKSAKEEQKRRRKGSGEGP--VEW
EDREDEPIKKKSDGPDNIIKRIFNILKFTWVLFLATVDSFTTWLNSISREHIDISTVLRI
ERCMLTREIKKGN-VPTRESI-HMYYQNHI-MNLSRESGLDTINDRPGAASGAQTAHRMD
SLD---SHDSISSCYTEATMLFSRQSTLDDLDGPETVPKTSERARPRLRKMFSMDMSSSS
ADSGSLASSEPTQCTMLYSRQGTTETIAEVEAEQDDEAVA-ADVDQGGEATG--------
-----NVGPEEASEGSEASEVGL--TP-DAELPQYPTEDGDVEAPPSYSKAVSFERLSFG
-SRDDSAGQSHMAVSPDDS-----RSDRLESSILPPLTHELTASELLLNKMFHDDE--LE
ESEKFYVGQPRFLLLFYAMYNTLVARSEMVCYFVIILNHMVSASMITLVLPILIFLWAML
SVPRPSRRFWMMAIVYTEVAIVVKYFFQFGFFPWNKNVEL--NKDKPYHPPNIIGVEKKE
GYVLYDLIQLLALFFHRS--ILKCHGLWDEDDITDSGTDKEESDDELSLS---RGRRASS
---DSLKSINLAASAE--------S---------VHVSFPEQS-TAI-RRKRSGSSSQIS
PRSSFSSNRSKR-----GS-TSTRNSSQKG--SSVLSIK-----QKSKRELY-MEKLQE-
--------------H-LIKAKAFTIKKTLQIYVPIRQFFYDLIHPDYSAVTDVYVLMFLA
DTVDFVIIVFGFWAFGK-HSAAADITSSLSEDQVPGPFLVMVLIQFGTMVVDRALYLRKT
VLGKVIFQVILVFGIHFWMFFILPGVTERKFSQNLVAQLWYFVKCVYFGLSAYQIRCGYP
TRVLGNFLTKSYNYVNLFLFQGF

PF12166 // ENSGT00390000013029_1_Domain_3 (2664, 3095)

RLVPFLTELRAVMDWVWTDTTLSLSSWICVEDIYAHI
FILKCWRESEKRYPQPRGQKKKKVVKYGMGGMIIVLLICIVWFPLLFMSLIKSVAGVINQ
PLDVSVTITLGGYQPIFTMSAQQSQLKVMDQTRFNKFMKA-----FSRDTGAMQFLENYE
KEDITVAELEGNSNSLWTISPPSKQKMIHELMDPNSSFSVVFSWSIQRNMSLGAKAEIAT
DKLSFLLKNNTRKNIAKMIAGNNTESSRTPVTIEKIYPYYVKAPSDSNSKPIKQLLS--E
NNFMNITI-------------TLSRDNTTKTNSEWWVLNLTGNRIYNQHAQALELVVFND
KVSPPSLGFLAGYGIMGLYASVVLVIGKFVREFFSGISHSIMFEELPNVDRILKLCTDIF
LVRETGELELEEDLYAKLIFLYRSPETMIKWTREKTN

----------MASEVVCGLIFRLLLPICLAVACAFRYNGLSFIYLIYLLLIPLFSEPTKA
T------MQGHTGRLLQSLCITSLSFLLLHIIFHIT-----LASLEAQHRIAPAYNCSTW
EKTFRQIGFE---SLKGADAGNGIRVFVPDIGMFIASLTIWLVCRTIVKKPDTEEVAQLN
SECENEELTGGEKMDSEEALIYE-EDLDGEEGMEGELEESTKLKILRRFASVASKLKEFI
GNMITTAGKVVVTFLLGS-SGMMLPSLTSAVYFFVFLGLCTWWSWCRTFDPLLFGCLCVM
LAIFTAGHLIGLYLYQFQFFQEAVPPNDYYA-RLFGIKSVIQTDCSSTWKIIVNPDLSWY
HHANPILLLVMYYTLATLI-RIWLQEPL--VQEEMVK------EDEGALDCSSNQN-TAE
RRRSLWYATQYPTDERKLLSMTQDDYKPSDGLLVTVNGNPVDYHTIHPSLPIENGPAKTD
LYTTPQYRWEPSEESSEKKEE-EEDKREDSEGEGSQEEKRSVRMHAMVTVFQFIMKQSYI
CALIAMM-AWSITYHSWLTFVLLIWSCTLWMIRNRRKYAMISSPFMVVYANLLLVLQYIW
SFELP--EIKKVPGFLEKKEPGELAS---------KILFTITFWLLLRQHLTEQKALREK
EAILSEVKIGSQELEEK----EDEELQDIQV---EGEPTG--------------------
--KEEEEEEEIKE---ERHEVKKEEEEEVEEDDDQDIMKVLGNLVVALFIKYWIYVCGGM
FFFVSFEGKIVMYKIIYMVLFLFCVALYQVHYEWWRKILKYFWMSVVIYTMLVLIFIYTY
QFENFPGLWQNMTGLKKEKLEDLGLKQFTVAELFTRIFIPTSFLLVCILHLHYFHDRFLE
LTDLKSIPSKEDNTIYSHAKVNGRVYLIIN-----------RLAHPEGSLPDLAIMNMTA
SLDRPEVQKLAEPGEERPEECIKKAE--KGGAGKDSDESEEEED-EE-------EESEEE
ESSDLRNKWHLVIDRLTVLFLKFLEYFHKLQVFMWWILELHIIKIVSSYIIWVTVKE--V
SLFNYVFLISWAFALPYAKLRRVASSVCTVWTCVIIVCKMLYQLQTIKPENFSVNCSLPN
ENQTNIP-LNELNKSLLYSAP-VDPTEWVGLRKSSPLLVYLRNNLLMLAILAFEVTVYRH
QEYYRGRNNLTAPVSKTIFHDITRLHLDDGLINCAKYFVNYFFYKFGLETCFLMSVNVIG
QRMDFYAMIHACWLIGVLYRRRRKAIAEVWPKYCCFLACIITFQYFVCIGIPPAPCRDYP
WRFKGAYFNDNIIKWLYFPDFIVRPNPVFLVYDFMLLLCASLQRQIFEDENKAAVRIMAG
DNVEICMNLDAASFSQHNPVPDFIHC-RSYLDMSKVIIFSYLFWFVLTIIFITGTTRISI
FCMGYLVACFYFLLFGGDLLLKPIKSILRYWDWLIAYNVFVITMKNILSIG

PF15917 // ENSGT00390000013029_1_Domain_0 (1492, 1775)

ACGYIGALV
RNSCWLIQAFSLACTVKGYQ--------MPEDDSRCKLPSGEAGIIWDSICFAFLLLQRR
VFMSYYFLHVVA--------DIKASQILASRGAELFQATIVKAVKARIEEEKKSMDQLKR
QMDRIKARQQKYKKGKERMLSLTQESGEGQDIQKVSEEDDE-READKQKAKGKKKQWWRP
WVDHASMVRSGDYYLFETDSEEEEEEELKKEDEEPPRKSAF-------------------
--------------QFVYQAWITDPKTALRQRRK

ENSGT00390000013029_1_Linker_0_3 (1775, 2665)

EKKKLAREEQKERRKGSGDGP--VEW
EDREDEPIKKKSDGPDNIIKRIFNILKFTWVLFLATVDSFTTWLNSISREHIDISTVLRI
ERCMLTREIKKGN-VPTRESI-HMYYQNHI-MKLSRESGLDTIDEHSGAGSRAQAAHRMD
SLD---SRDSISSCYTEATLLISRQSTLDDLDGQDPVPKTSERARPRLRKMFSMDMSSSS
ADSGSVASSEPTQCTMLYSRQGTTETIEEVEAEAEEEMVGDLEPELHDAEEK--------
-----EYAAE---YEAGVEEISLTPD---EELPQFSTDDCDVEAPPSYSKAVSFEHLSFA
SQDD-SGAKNHMVISPDDSRTD-----KLESSILPPLTHELTASDLLMSKMFHDDE--LE
ESEKFYVDQPRFLLLFYAMYNTLVARSEMVCYFVIILNHMTSASIITLLLPILIFLWAML
SVPRPSRRFWMMAIVYTEVAIVVKYFFQFGFFPWNKDLEI--YKERPYFPPNIIGVEKKE
GYVLYDLIQLLALFFHRS--ILKCHGLWDEDDIVDSNTDKEGSDDEL---SLDQGRRGSS
---ESLKSINLAASVES-----------------VHVTFPEQPAAIRRKR--SCSSSQIS
PRSSFSSNRSKR-----GST-STRNSSQKG--SSVLSLK-----QKSKRELY-MEKLQEH
LIKAKAF----------------TIKKTLQIYVPIRQFFYDLIHPDYSAVTDVYVLMFLA
DTVDFIIIVFGFWAFGK-HSAAADITSSLSEDQVPGPFLVMVLIQFGTMVVDRALYLRKT
VLGKVIFQVILVFGIHFWMFFILPGVTERKFSQNLVAQLWYFVKCVYFGLSAYQIRCGYP
TRVLGNFLTKSYNYVNLFLFQGFR

PF12166 // ENSGT00390000013029_1_Domain_3 (2665, 3094)

LVPFLTELRAVMDWVWTDTTLSLSSWICVEDIYAHI
FILKCWRESEKRYPQPRGQKKKKAVKYGMGGMIIVLLICIVWFPLLFMSLIKSVAGVINQ
PLDVSVTITLGGYQPIFTMSAQQSQLKVMNNSKYNEFLKS-----FGPNSGAMQFLENYE
KEDITVAELEGNSNSLWTISPPSKQKMIQELTDPNSCFSVVFSWSIQRNMTLGAKSEIAT
DKLSFPLANATRNSIAKMIAGNDTESSNTPVTIEKIYPYYVKAPSDSNSKPIKQLLS--E
NNFMNITI-------------ILFRDNVTKSNSEWWVLNLTGSRIFNQGSQALELVVFND
KVSPPSLGFLAGYGIMGLYASVVLVIGKFVREFFSGISHSIMFEELPNVDRILKLCTDIF
LVRETGELELEEDLYAKLIFLYRSPETMIKWTREKTN

------------------------------------------------------------
------------------------------------------------------------
--------------------------------MFIASLTIWLICRNMFQKPVTEDAAQCN
MQFENEEMAVREKLEPDDALMYE-EDLDDDDCGEAEFEETMKLKLLRRIAFLASKLREFI
GNMIITTGKVVVTILLGS-AGMMVPSLTSAVYFFVFLGLCTWWSCCQAFDPLIFSCLCVL
MAIFSAGHLIGLYLYQLQFFQEVVPPKDFYA-RLFGVTSLTQTNCSSTWMIIKNQELHWY
HHANPILLLVMYYTLATLI-RLWLQEPI--QTP--DEEKSVGREEDKEI-PCSPIPMTAE
RRRSLWYASHYTTDERKLLSMTQDEYKPSDVLLVTVNGNPADYHTIHPALPLENGPGKAD
MYSTPQYKWEPSDGTSEKEEE-E-----EEEEEVTQEEKENVKLHALVSVFQFIMKQSYI
CALIAMM-AWSITYHSWLTFVLLIWSCTLWMIRDRRKYAMISSPFMVFYGNLLLILQYIW
SIKLRNDELPQVSGFLIRKEPGELAS---------KILFTITFWLLLRQHLTEQKALRLK
EATLSEVKVGSEENEEK----EEESQE--------GEVS----EEQEE------------
--------------------EKEEEEEGEEEEDEQDIMKVLGNLVMAMLIKYWIYVCGGM
FFFVSFEGTIVMYKIIYMVLFLFCVALYQVHYEWWRKILKYFWMSVVVYTMLVLIFIYTY
QFESFPGLWKNMTGLDEGKLEDLGLKQFSVGDLFTRIFIPTSFLLVCILHLHYFHDQFLQ
ITDLKAVTSKQDNTIY-------------------------RLVHQDGSLPDITMMNLTA
SREKEEDKMLEEAGEKRMEEPEGEGGKGRVKKGKEEEKEDEDKEQDDDDDDDEDNESEEE
ETTDLRNKWHLVIDRLTVLFLKFLEYFHKMQVFVWWLLELHIIKIVSSYIIWVTVKE--V
SLFNFVFLIAWALALPYAQFRPLASSICTVWTCVIIVCKMLYQLTSIDPKTFSSNCTLPG
ENETKVD-LEELKTSVLYSGP-VDPAEWVGLRKSYPLLVYLRNNLLMLAILAFEVTIYRH
QEYYRCRNNLTTPVTKTIFHDITRAHLDDGLVNCVKYFINYFFYKFGLETCFLLSVNVIG
QRMDFYAMIHAFWLIAVLYRRRRKAIAEIWPKYCCFLACIITFQYFLCIGIPPAPCKDYP
WRSGNANFNSNIIKWLYFPDFIVRPNPVFLVYDFMLLLCASLQRQTFEDENKAAVRIMAG
DNVEICMNLDAASFSQHNPVPDFIHC-RSYLDMYKVIIFSYLFWFVLTIIFITGTTRISI
FCMGYLVACFYFLLFGGDLLLKPIRSILRYWDWLIAYNVFVITMKNILSIGACGYIESLI
ENSCWVIQAFSLACTVKGYHIPT--------GNLDCKLPSGEAGIIWDSICFAFLLLQRR
VFMSYYFLHVVA--------DIKASQILASRGAELFQATIVKAVKARIEEEKKSMDQLKR
QMDRIKARQQKYKKGKERMLSMNQESTEGPEIRKVSEEDDE-GDADKEKAKGKKKLWWRP
WVDHASMVRSGNYYLFETDSEEEEEEE-KKEEEEPRKKSAF-------------------
--------------QFVYQAWITDPKTALRQRRKEKKSFGKEKRRRKGSGDGGGND-ADC
EDSEEEPVKKKSDGPDNIIKRIFNILKFTWVLFLATLDSFTAWLNSISREHIDISTVLRI
ERCMLTREIKKGN-VPTRESI-HLYYQNHM-MKLSEESGLDSIDKNPSQASGLQASERMD
SLDSAASHDSI-------------------------------------------------
-------SSEPTQVTLLYSRQGTTETIEEVEGEHEEEGAHSASRLEEEE-VE--------
-----DYSLDSE-------G-AA--YTPDTDVPLYSTVDSNAEAPPSYSKAVSFEHLPFG
-SPDDSAGKSLMMVSPDDSRTD-----KL-DTILPPLTHELTASELLLNKMFHDDE--LE
ESEKFYVGQPRVLLLIYALYNTLVARSEMVCYFVIILNHMISASMITLVLPILIFLWAML
SVPRPSKRFWMTAIVYTEVAIVIKYFFQFGFFPWNKHVDY--TKDKPYHPPNIIGIEKKE
GYVHYDLVQLLALFFHRS--ILKCHGLWDEDEKGDSSSNKEDTDDEL---SLTGGRRDSS
---ASLKSVNLAASVES-----------------IHVHFPEQQTAIRRKS--SSSISQLS
HRSSFSSHRSKR-----GST-STRNSSQKG--SSVLSIK-----QKSRKELL-MEKFREQ
MIKAKAFTIKK----------------TLQVYVPIRQFFYNLIHPDYSAVTDVYVLMFLA
DTVDFIIIVFGFWAFGK-HSAAADITSSLSEDQVPEAFLVMVLIQFGTMVVDRALYLKKT
VMGKVIFQVILVFGIHFWMFFILPGVTERKFSQNTVAQLWYFVKCVYFGLSAYQIRCGYP
TRVLGNFLTKSYNYVNLFLFQGF

PF12166 // ENSGT00390000013029_1_Domain_3 (2664, 3095)

RLVPFLTELRAVMDWVWTDTTLSLSSWICVEDIYAHI
FILKCWRESEKRYPQPRGQKKKKVVKYGMGGMIIVLLICIVWFPLLFMSLIKSVAGITNK
PLDVSITITLGGYQPIFTMSAQQNQLKSLDPNEFNEFLKS-----YRGNTAALQFLEGYA
REDITRADLEGNSNSLWTISPPSRQKMIQGLRDFDADFSLVISWTIQRNLSLGAKAEIAS
DKLTFTLKNHTREHIARMMEGNET-EKVEKVTLEEVYPYYIKAPSDSLAKPIKQLL--KD
CKWENITV-------------SLVKNTS----EEWWVLDQLGKR-QKVSHESLELFIFSD
KVSPPSLGFLAGYGIMGLYASVVLVIGKFVREFFSGISHSIMFEELPNVDRILKLCTDIF
LVRETGELELEEDLYAKLIFLYRSPETMIKWTREKTN

------------------------------------------------------------
----------MVSRSNKCSCFTTELLKSFSIIFNYR----------------------NI
RTKFSPLPFFFLYSLKGADAGNGIRVFVPDIGMFIASLTIWLLCRNIVQKPVTDEAAQSN
LEFENEELAGGEKIDSEEALIYE-EDFHGGDGVEGELEESTKLKMFRRLASVASKLKEFI
GNMITTAGKVVVTILLGS-SGMMLPSLTSSVYFFVFLGLCTWWSWCRTFDPLLFSCLCVL
LAIFTAGHLIGLYLYQFQFFQEAVPPNDYYA-RLFGIKSVIQTDCSSTWKIIVNPDLSWY
HHANPILLLVMYYTLATLI-RIWLQEPL--VQDERTK------EEDKALACSPIQI-TAE
RRRSLWYATHYPTDERKLLSMTHDDYKPSDGLLVTVNGNPVDYHTIHPSLPMENGPGKAD
LYSTPQYRWEPSDESSEKREE-EEEEKEEFEEERSREEKRSIKVHAMVSVFQFIMKQSYI
CALIAMM-AWSITYHSWLTFVLLIWSCTLWMIRNRRKYAMISSPFMVVYGNLLLILQYIW
SFELP--EIKKVPGFLEKKEPGELAS---------KILFTITFWLLLRQHLTEQKALQEK
EALLSQVKIGSQENEEK-----DEELQDIQV---EGEPKEK-------------------
-----EEEEEAKEEKQERKKVEQEE---AEEEDEQDIMKVLGNLVVAMFIKYWIYVCGGM
FFFVSFEGKIVMYKIIYMVLFLFCVALYQVGTQLAILIL---TSVLVIYTMLVLIFIYTY
QFENFPGLWQNMTGLKKEKLEDLGLKQFTVAELFTRIFIPTSFLLVCILHLHYFHDRFLE
LTDLKSIPSKEDNTIYR-------------------------LAHPEGSLPDLTMMHLTA
SLEKPEVRKLAEPGEEKPEGYSEKAQ--KGDLGKDSEESEEDGQ-EE-----EESEE-EE
ETSDLRNKWHLVIDRLTVLFLKFLEYFHKLQVFMWWILELHIIKIVSSYIIWVSVKE--V
SLFNYVFLISWAFALPYAKLRRLASSVCTVWTCVIIVCKMLYQLQTIKPENFSVNCSLQS
KADTW-------------GTPIPKHNLWVGLRKSSPLLVYLRNNLLMLAILAFEVTIYRH
QEYYRGRNNLTAPVSKTIFHDITRLHLDDGLINCAKYFINYFFYKFGLETCFLMSVNVIG
QRMDFYAMIHACWLIAVLYRRRRKAIAEIWPKYCCFLACIITFQYFICIGIPPAPCRDYP
WRFKGASFNDNIIKWLYFPDFIVRPNPVFLVYDFMLLLCASLQRQIFEDENKAAVRIMAG
DNVEICMNLDAASFSQHNPVPDFIHC-RSYLDMSKVIVFSYLFWFVLTIIFITGTTRISI
FCMGYLVACFYFLLFGGDLLLKPIKSILRYWDWLIAYNVFVITMKNILSIG

PF15917 // ENSGT00390000013029_1_Domain_0 (1492, 1775)

ACGYIGTLV
HNSCWLIQAFSLACTVKGYQ--------MPAANSPCTLPSGEAGIIWDSICFAFLLLQRR
VFMSYYFLHVVA--------DIKASQILASRGAELFQATIVKAVKARIEEEKKSMDQLKR
QMDRIKARQQKYKKGKERMLSLTQEPGEGQDMQKLCEEDDE-READKQKAKGKKKQWWRP
WVDHASMVRSGDYYLFETDSEEEEEEELKKEDEEPPRRSAF-------------------
--------------QFVYQAWITDPKTALRQRHK

ENSGT00390000013029_1_Linker_0_3 (1775, 2665)

EKKRSAREERKRRRKGSKEGP--VEW
EDREDEPIKKKSDGPDNIIKRIFNILKFTWVLFLATVDSFTTWLNSISREHIDISTVLRI
ERCMLTREIKKGN-VPTRESV-HMYYQNHI-MNLSRESGLDTIDEHPGAASGAQTAHRMD
SLD---SHDSIS------------------------------------------------
--------SEPTQCTMLYSRQGTTETIEEVEAEQEEEAGSTAPEPREAKEYK--------
-------AAGYDVGAVGAEEASLTPE---EELTQFSTLDGDVEAPPSYSKAVSFEHLSFG
SQDD-SAGKNHMAVSPDDSRTD-----KLGSSILPPLTHELTASELLLNKMFHDDE--LE
ESEKFYVRQPRFLLLFYAMYNTLVARSEMVCYFVIILNHMVSASMITLLLPILIFLWAML
SVPRPSRRFWMMAIVYTEVAIVVKYFFQFGFFPWNKNAEV--NKDKPYHPPNIIGVEKKE
GYVLYDLIQLLALFFHRS--ILKCHGLWDEDDMTESGMDKEESDDEL---SLGHGRRDSS
---DSLKSINLAASVES-----------------VHVTFPEQQTAVRRKR--SGSSSEPS
RRSSFSSNRSQR-----GST-STRNSSQKG--SSVLSIK-----QKSKRELY-MEKLQEH
LIKAKAF----------------TIKKTLQIYVPIKQFFYNLIHPDYSAVTDVYVLMFLA
DTVDFIIIVFGFWAFGK-HSAAADITSSLSEDQVPGPFLVMVLIQFGTMVVDRALYLRKT
VLGKVIFQVILVFGIHFWMFFILPGVTERKFSQNLVAQLWYFVKCVYFGLSAYQIRCGYP
TRVLGNFLTKSYNYVNLFLFQGFR

PF12166 // ENSGT00390000013029_1_Domain_3 (2665, 3094)

LVPFLTELRAVMDWVWTDTTLSLSSWICVEDIYAHI
FILKCWRESEKRYPQPRGQKKKKVVKYGMGGMIIVLLICIVWFPLLFMSLIKSVAGVINQ
PLDVSVTITLGGYQPIFTMSAQQSQLKVMDQQNFNKFIQA-----FSRDTGAMQFLENYE
KEDITVAELEGNSNSLWTISPPSKQKMIHELLDPNSSFSVVFSWSIQRNLSLGAKSEIAT
DKLSFPLKNITRKNIAKMIAGNSTESSKTPVTIEKIYPYYVKAPSDSNSKPIKQLLS--E
NNFMDITI-------------ILSRDNTTKYNSEWWVLNLTGNRIYNPNSQALELVVFND
KVSPPSLGFLAGYGIMGLYASVVLVIGKFVREFFSGISHSIMFEELPNVDRILKLCTDIF
LVRETGELELEEDLYAKLIFLYRSPETMIKWTREKTN

----------MASEVVCGLIFRLLLPICLAVACAFRYNGLSFVYLIYLLLIPLFSEPTKV
T------MQGHTGRLLKSLCFTSLSFLLLHIIFHIT-----LASLEAQHRIAPGYNCSIW
EKTFRQIGF---ESLKGADAGNGIRVFVPDIGMFIASLTIWLVCRNIVQKPIIEEAAQYN
LEFESEELTGGEKIDSEEALIYE-EDLDGGDGGEGELEESTKLKIFRRLASVASKLKEFI
GNMITTAGKVVVTILLGS-SGMMLPSLTSSVYFFVFLGLCTWWSWCRTFDPLLFSCLCVL
LAIFTAGHLIGLYLYQFQFFQEAVPPNDYYA-RLFGIKSVIQTDCSSTWKIIVNPELSWY
HHANPILLLVMYYTLATLI-RIWLQEPL--VQDERPR------EEDRALACSPIQI-TAE
RRRSLWYATHYPTDERKLLSMTQDDYKPSDGLLVTVNGNPVDYHTIHPSLPMENGPGKAD
LYSTPQYRWEPSDEPSEKKEE-EEEEKEEFEEEQSHEEKRSVKVHAMVSVFQFIMKQSYI
CALIAMM-AWSITYHSWLTFVLLIWSCTLWMIRNRRKYAMISSPFMVVYGNLLLILQYIW
SFELP--EIKKVPGFLEKKEPGELAS---------KILFTITFWLLLRQHLTEQKALQEK
EALLSEVKIGSQENEEK-----DEELQDIQV---EGEPRKE-------------------
-----EEEEEAKEEKQERKKEEKEEEEEEEEEDDQDIMKVLGNLVVAMFIKYWIYVCGGM
FFFVSFEGKIVMYKIIYMVLFLFCVALYQVHYEWWRRILKYFWMSVVIYTMLVLIFIYTY
QFENFPGLWQNMTGLKKEKLEDLGLKQFTVAELFTRIFIPTSFLLVCILHLHYFHDRFLE
LTDLKSIPSKEDNTIYSHAKVNGRVYLIINSIKKKLPIHQNELAHPEGSLPDLTMMNLAA
SLEKPEVRKLAEPREEKPEGCSEKAE--KGELGKDSEESEDGE--------EE-ESEEEE
ETSDLRNKWHLVIDRLTVLFLKFLEYFHKLQVFMWWILELHIIKIVSSYIIWVSVKE--V
SLFNYVFLISWAFALPYAKLRRLASSICTVWTCVIIVCKMLYQLQTIKPENFSVNCSLPN
ENQTNIP-LQDLNKSLLYNAS-IDPTEWVGLRKSSPLLVYLRNNLLMLAILAFEVTIYRH
QEYYRGRNNLTAPVSKTIFHDITRLHLDDGLINCAKYFINYFFYKFGLETCFLMSVNVIG
QRMDFYAMVHACWLIAVLYRRRRKAIAEVWPKYCCFLACIITFQYFICIGIPPAPCRDYP
WRFKGASFNDNIIKWLYFPDFIVRPNPVFLVYDFMLLLCASLQRQIFEDENKAAVRIMAG
DNVEICMNLDAASFSQHNPVPDFIHC-RSYLDMSKVIIFSYLFWFVLTIIFITGTTRISI
FCMGYLVACFYFLLFGGDLLLKPIKSILRYWDWLIAYNVFVITMKNILSIG

PF15917 // ENSGT00390000013029_1_Domain_0 (1492, 1775)

ACGYIGTLV
QNSCWLIQAFSLACTVKGYK--------MPDDDSPCKLPSGEAGIIWDSICFAFLLLQRR
VFMSYYFLHVVA--------DIKASQILASRGAELFQATIVKAVKARIEEEKKSMDQLKR
QMDRIKARQQKYKKGKERMLSLTQEPGEGQDTRKLSEEDDE-READKQKAKGKKKQWWRP
WVDHASMVRSGDYYLFETDSEEEEEEELKKEDEEPPRRSAF-------------------
--------------QFVYQAWITDPKTALRQRRK

ENSGT00390000013029_1_Linker_0_3 (1775, 2665)

EKKRSAREEQKRKQKGSGEGA--MEW
NDQEEERVKKKSDGPDNIIKRIFNILKFTWVLFLATVDSFTTWLNSISREHIDISTVLRI
ERCMLTREIKKGN-VPTRESI-HMYYQNHI-MNLSRESGLDTIDERPGAASGAQTAHRMD
SLD---SHDSIS------------------------------------------------
--------SEPTQCTMLYSRQGTTETIEEVEAEQEEEARGTAPEPTGADGESEAE-----
------DQAEDEAGALSLEEAGLTPE---EELAQFSAVDRDVEVPPSYSKAVSFEHLSFA
SQDD-STGKNHMVVSPDDSRTD-----KLESSILPPLTHELTASELLLNKMFHDDE--LE
ESEKFYMEQPRFLLLFYAMYNTLVARSEMVCYFVIILNHMVSASMITLLLPILIFLWAML
SVPRPSRRFWMMAIVYTEVAIVVKYFFQFGFFPWNKHVEL--YKDKPYHAPNIIGVEKKE
GYVLYDLIQLLALFFHRS--ILKCHGLWDEDDIVESGSDQEDSDDEL---SLARGRRDSS
---DSLKSINLATSVES-----------------VHVTFPEQPAAIRRKC--SGSSSQIS
QRSSFSSNRSKR-----GST-STRNSSQKG--SSVLSIK-----QKSKREFY-MEKLQEH
LIKAKAF----------------TIKKTLQIYVPIRQFFYNLIHPEYSAVTDVYVLMFLA
DTVDFIIIVFGFWAFGK-HSAAADITSSLSEDQVPGPFLVMVLIQFGTMVVDRALYLRKT
VLGKVIFQVILVFGIHFWMFFILPGVTERKFSQNLVAQLWYFVKCVYFGLSAYQIRCGYP
TRVLGNFLTKSYNYVNLFLFQGFR

PF12166 // ENSGT00390000013029_1_Domain_3 (2665, 3094)

LVPFLTELRAVMDWVWTDTTLSLSSWICVEDIYAHI
FILKCWRESEKRYPQPRGQKKKKVVKYGMGGMIIVLLICIVWFPLLFMSLIKSVAGVINQ
PLDVSVTITLGGYQPIFTMSAQQSQLKVMDQPTFNSFLKN-----FSRDTGAMQFLENYE
KEDITVAELEGNSNSLWTISPPSKQKMIHELMDPNSSFSVVFSWSIQRNLSLGAKSEIAT
DKLSFPLKNITRESIAKMIAGNNTESSKTPVTIEKIYPYYVKAPSDSNSKPIKQLLS--E
NNFMDITI-------------ILSRDNTTKSNSEWWVLNLTGNRIYNQHSQALELVVFND
KVSPPSLGFLAGYGIMGLYASVVLVIGKFVREFFSGISHSIMFEELPNVDRILKLCTDIF
LVRETGELELEEDLYAKLIFLYRSPETMIKWTREKTN

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--QIK-PELSVEANM-AKL--RLLYLSHLKSPALVKILFAITFWLLLRQHLTEQKALRLK
EAVLSEVKVEEE------------------------------------------------
-----------------------------GSEEEEDVMKVLGNLVMAMFVKYWIYVCGGM
FFFVSFEGKIVMYKIIYMMLFLFCVVLYQVHYEWWRQILKYFWMSVVVYTMLVLVLIYTY
QFDSFPTLWKNATGMNDEQLKDLGLEQFSVGELFTRIFIPTSFLLVCILHLHYFHDRFLQ
LTDLKAIISKQDSAIYRWIHRHQEKITNP------------------------------P
NIEKED-------------S---E-----HE---KEENENEKEEEEGDEEEYDEDESETE
ETSGNLNKWHLVIDRLTVLFLKFLECFHKLQVFVWWILELHIIKIVSSYIIWVTVKE--V
SLLNYAFLIAWAFALPYSQFRPLASSVCTVWTCVIIICKMFYQLESINTANFSVNCTMPN
TTV---K-PEVLSESLLYRKP-IDPTEWVGLKKSYPLLVYLRNNLLMLAILAFEVTIYRH
QEYYRCRNNLTAPDTKTIFHDITRLHLDDGVISCLKYFINYFFYKFGLESCFLLSVNVIG
QRMDFYAMIHAFALIVVLYRRRRKAIAEVWPKYCCFLACIITFQYFMCIGIPPAPCKDYP
WRNPNSNFNSNIIKWLYFPDFIQRPNPVFLVYDFMLLLCASLQRQTFEDENKAAVRIMAG
DNVEICMNLDAASFSQHNPVPDFIHC-RSYLDMGKVIMFSYLFWFVLTIIFITGTTRISI
FCMGYLIACFYFLLFGGDLLLKPIRSILRYWDWLIAYNVFVITMKNVLSIGACGYIGSLI
KNSCWVIQIFSLSCTVKGYEIQK---QVSSNKDSECKIPSGEAGIIWDSICFAFLLLQRR
VFMSYYFLHVVA--------DIKASQILASRGAELFQATIVKAVKARIEEEKKSMDQLKR
QMDRIKARQQKYKKGKERVLSMNQEASEGQAIQNLG-------EADKEKAKGKKKQWWRP
WVDHASMVRSGDYYLFETDSEEEEEDE-KKEEEEPPKRSAF-------------------
--------------QFVYQAWITDPKTALRQRRKEKKKIEK-EGRRRRKGSGDVSI-DVE
GEDREEPAKKKSDGPDNIIKRIYNILKFTWVLFLATIDSFTAWLNSISREHIDISTVLRI
ERCMLTREIKKGSHKHLT------------------------------------------
--------------ILKKLYLSTRQSTLDDLDGPEPIPKTTL------------------
------------------------------------------------------------
--------------------------------------DGIAEPPPSYSKVVSLELLPLD
DSQDDSSDKNQMMVSPDENQS-----IKLEDSILPPLTHELTASDLLVNKMFKDEE--LD
ESEKFYADQPRFLLLIYALYNTLVARSEMVCYFVIILNHMISASMITLVLPILIFLWAML
SVPRPSKRFWMTAIVYTEVAIVIKYFFQFGFFPWNANVEI--KKDKPDHPPNIIGIDKKE
GYVHYDLVQLLALFFHRS--ILKCHGLWDDEDGGDNISSKDDSDDELAE----SDRRGSS
---DSLTSVNLATSVES-----------------IHVHFPEQQAAVRRKSSSSG------
--SSHSSHRSKR-----GTYYKSEWE--FGFSILELERG-----QRKKKDGLGRHRLSS-
--NCKTICTQL-TQQGREMQSFFCYFRTLQVYVPIKQFFYNLIHPDYSAVTDVYVLMFLA
DTVDFIIIVFGFGAFGK-HSAAADITSSLSEDQVPQAFLVMVLIQFGTMVVDRALYLRKT
VMGKVIFQVILVFGIHFWMFFILPIVTERKFSKNTVAQLWYFVKCVYFGLSAYQIRCGYP
TRVLGNFLTKSYNYVNLFLFQGF

PF12166 // ENSGT00390000013029_1_Domain_3 (2664, 3095)

RLVPFLTELRAVMDWVWTDTTLSLSSWICVEDIYAHI
FILKCWRESEKRYPQPRGQKKKKAVKYGMGGMIIVLLICIVWFPLLFMSLIKSVAGVTNK
PLDVSITITLGGYQPIFTMSAQQSQLRNMTGKEYSDFLRK-----FK-DNSALQFLENYG
KEDITVAQLEGSSNSLWTISPPSRKNMIKELKANDSDFSLVISWSVQRNLSLGAKAEIAS
DKVSLSLPINTRIKIAEMMEQS---SSSNLVTLEEVYPHYIKAPSDSVAKPIKQLLRKSK
DENITVSLSKN------------TVSGNESDLREWWVLNQTYKH-LDKDRTRLELIVFSD
KVSPPSLGFLAGYGIMGLYASVVLVIGKFVREFFSGISHSIMFEELPNVDRILKLCTDIF
LVRETGELELEEDLYAKLIFLYRSPETMIKWTREKTN

------------------------------------------------------------
-------MQGHTGRLLKSLCFTSLSFLLLHIIFHIT-----LASLEAQHRIAPGYNCSTW
EKTFRQIGFE---SLKGADAGNGIRVFVPDVGMFIASLTIWLVCRNIVQKPVAEEAAQCN
PEFENEESAGGEKIDSEEALIYE-EDLDEGDGAEGDLEESTKLKLFRRLASVASKLKEFI
GNMITTAGKVVVTILLGS-SGMMLPSLTSSVYFFVFLGLCTWWSWCRTFDPLLFSCLCVL
LAIFTAGHLIGLYLYQFQFFQEAVPPNDYYA-RLFGIKSVIQTDCSSTWKIIANPDLSWY
HHANPIVLLVMYYTLATLI-RIWLQEPV--VQEEKTKE------EDRALACSPAPI-TAE
RRRSLWYATHYPTDERKLLSMTQDDYKPSDGLLVTVNGNPVDYHTIHPSLPLENGPAKAD
LYSTPQYRWEPATASPEKKEE-DNDEKEEFEEERSREEKRSVKVHAMVSVFQFIMKQSYI
CALIAMM-AWSITYHSWLTFVLLIWSCTLWMIRNRRKYAMISSPFMVVYGNLLLILQYIW
SFELP--EIKKVPGFLEKKEPGELAS---------KILFTITFWLLLRQHLTEQKALQEK
EALLSEVKIGSQENEEK-----DD-EQDVQVD---SEAQEE-EGEEPKEEQQE-------
-------------------RR-EEE--EEEEADEQDVMKVLGNLVVALFIKYWIYVCGGM
FFFVSFEGKIVMYKIIYMVLFLFCVALYQVHYEWWRRILKYFWMSVVIYTMLVLIFIYTY
QFENFPGLWQNMTGLKKEKLEDLGLKQFTVAELFTRIFIPTSFLLVCILHLHYFHDRFLE
LTDLKSIPSKEDSAVYSHAKVNGRVYLIIN-----------RLAHPEGSLPDLAMMKLTA
SLEVAEVKQLAGPGEEMPGGCPAKAKK--GEP--GRDSEDEDEDEDEE-------DEEEE
ETSDLRNKWHLVIDRLTVLLLRFLEGFHQLQTFLWWILELHIVKIVSSYIIWVSVKE--V
SLFNYVFLISWAFALPYAKLRRLASSVCTVWTCVIIVCKMLYQLQTIKPENFSVNCSLPN
ENQTNIP-LHQLNKSLLYSAP-IDPTEWVGLRKSSPLLVYLRNNLLMLAILAFEVTIYRH
QEYYRGRNNLSTPVSKTIFHNITRLQLDDGLVNCAKYFINYFFYKFGLETCFLMSVNVIG
QRMDFYAMIHACWLIAVLYRRRRKAIAEIWPKYCCFLACIITFQYFICIGIPPAPCRDYP
WRFKGASFNDNIVKWLYFPDFIVRPNPVFLVYDFMLLLCASLQRQIFEDENKAAVRIVAG
DNVEICMNLDAASFSQHNPVPDFIHCSRSYLDMSKVVIFSYLFWFVLTIIFITGTTRISI
FCMGYLVACFYFLLFGGDLLLKPIKSILRYWDWLIAYNVFVITMKNILSIGACGYIEKLV
QNSCWLIQAFSLACTVKGYKM--------PDDDSSCKLPSGEAGIIWDSICFAFLLLQRR
VFMSYYFLHVVA--------DIKASQILASRGAELFQATIVKAVKARIEEEKKSMDQLKR
QMDRIKARQQKYKKGKERMLSLTQESGEGQDLQKLSEEDDE-READKQKTKGKKKQWWRP
WVDHVSMVRSGDYYLFETDSEEEEEEELKKEDEEPPRRSAF-------------------
--------------QFVYQAWITDPKTALRQRRKEKKRSAREEQKRRRKVSGEGP--VEW
EDREDEPVKKKSDGPDNIIKRIFNILKFTWVLFLATVDSFTTWLNSISREHIDISTVLRI
ERCMLTREIKKGN-VPTRESI-HMYYQNHI-MNLSRESGLDTIDDHAGAAAGAQTAHRMD
SLD---SHDSISSCYTEATMLFSRQSTLDDLDGPETVPKTSERARPGLRKMLSMDVSSSS
AESTSLGSSEPTQCTMLYSRQGTTETIEEVEAEQDEETSE-G------------------
-------------------------AR-QAESPQDPTEDGDVEAPPSYSKAVSFERLSFD
-SRDDSAGQTHMEVSPDDS-----RSDRLEASILPPLTHELTASELLLNKMFHDDE--LE
ESEKFYVGQPRFLLLFYALYNTLVARSEMVCYFVIILNHMVSASMITLVLPILIFLWAML
SVPRPSRRFWMMAIVYTEVAIVVKYFFQFGFFPWNKNVEL--NKDKPYHPPNIIGVEKKD
AYVLYDLIQLLALFFHRS--ILKCHGLWDEDDIVDSGSDKVDSDDELSLG---HGRRASS
---DSLKSINLAASVE--------S---------VHVTFPEQP-AAVR-RKRSSSGSQTS
QESSFSSNRSKR-----GS-TSTRNSSQKG--SSVVSVK-----QKSRRELY-MEKLQE-
--------------H-LIKAKAFTIKKTLQLYVPIRQFFYDLIHPDYSAVTDVYVLMFLA
DTVDFIIIVFGFWAFGK-HSAAADITSSLSEDQVPGPFLVMVLIQFGTMVVDRALYLRKT
VLGKVIFQVILVFGIHFWMFFILPGVTERKFSQNLVAQLWYFVKCVYFGLSAYQIRCGYP
TRVLGNFLTKSYNYVNLFLFQGF

PF12166 // ENSGT00390000013029_1_Domain_3 (2664, 3095)

RLVPFLTELRAVMDWVWTDTTLSLSSWICVEDIYAHI
FILKCWRESEKRYPQPRGQKKKKVVKYGMGGMIIVLLICIVWFPLLFMSLVKSVAGVINQ
PLDVSVTITLGGYQPIFTMSAQQSQLKVMDQPMFNKFIKA-----FSKDTGAMQFLENYE
KEDITVAELEGNSNSLWTISPPSKQKMIHELKDPNSSFSVVFSWSIQRNMSLGAKAEIAT
DKLSFPLKNKTRENIAKMIAGGDTESSRTPVTIERIYPYYVKAPSDSNSKPIKQLLS--E
NNFMNITI-------------ILSRDNATNSNSEWWVLNLTGNRIYNQEAQALELVVFND
KVSPPSLGFLAGYGIMGLYASVVLVIGKFVREFFSGISHSIMFEELPNVDRILKLCTDIF
LVRETGELELEEDLYAKLIFLYRSPETMIKWTREKTN

----------MASEVVCGLIFRLLLPICLAVACAFRYNGLSFVYLIYLLLIPLFSEPTKT
T------MQGHTGRLLKSLCFISLSFLLLHIIFHIT-----LASLEAQHRIAPGYNCSTW
EK---TFRQIGFESLKGADAGNGIRVFVPDIGMFIASLTIWLLCRNIVQKPVTDEAAQSN
LEFENEELAGGEKIDSEEALIYE-EDLDGGDGVEGELEESTRLKMFRRLACVASKLKEFI
GNMITTAGKVVVTILLGS-SGMMLPSLTSSVYFFVFLGLCTWWSWCRTFDPLLFSCLCVL
LAIFTAGHLIGLYLYQFQFFQEAVPPSDYYA-RLFGIKSVIQTDCSSTWKIIVNPDLSWY
HHANPILLLVMYYTLATLI-RIWLQEPL--VQEERTK------EEDKALACSPIQI-TAE
RRRSLWYATHYPTDERKLLSMTQDDYKPSDGLLVTVNGNPVDYHTIHPSLPMENGPGKAD
LYSTPQYRWEPSDESSEKREE-EEEEKEEFEEERSREEKRSIKVHAMVSVFQFIMKQSYI
CALIAMM-AWSITYHSWLTFVLLIWSCTLWMIRNRRKYAMISSPFMVVYGNLLLILQYIW
SFELP--EIKKVPGFLEKKEPGELAS---------KILFTITFWLLLRQHLTEQKALREK
EALLSEVKIGSQENEEK-----DEELQDIQV---EGEPKEE-------------------
-----EEEEEAKEEKQERKKVEEEE---VEEEDEQDIMKVLGNLVVAMFIKYWIYVCGGM
FFFVSFEGKIVMYKIIYMVLFLFCVALYQVHYEWWRKILKYFWMSVVIYTMLVLIFIYTY
QFENFPGLWQNMTGLKKEKLEDLGLKQFTVAELFTRIFIPTSFLLVCILHLHYFHDRFLE
LTDLKSIPSKEDNTIYSHAKVNGRVYLIINSIKKKLPIHQNELAHPEGSLPDLTMMHLTA
KLEKPEVRKLAEPGEEKPEGYSEKAQ--KGDLGKDSEESEEDGE-EE-----EESEE-EE
ETSDLRNKWHLVIDRLTVLFLKFLEYFHKLQVFMWWILELHIIKIVSSYIIWVSVKE--V
SLFNYVFLISWAFALPYAKLRRLASSVCTVWTCVIIVCKMLYQLQTIKPENFSVNCSLPN
ENQTNIP-LNELNKSLLYSAP-VDPTEWVGLRKSSPLLVYLRNNLLMLAILAFEVTIYRH
QEYYRGRNNLTAPVSKTIFHDITRLHLDDGLINCAKYFINYFFYKFGLETCFLMSVNVIG
QRMDFYAMIHACWLIAVLYRRRRKAIAEIWPKYCCFLACIITFQYFICIGIPPAPCRDYP
WRFKGASFNDNIIKWLYFPDFIVRPNPVFLV-----------------------------
----------------------------SYLDMSKVIVFSYLFWFVLTIIFITGTTRISI
FCMGYLVACFYFLLFGGDLLLKPIKSILRYWDWLIAYNVFVITMKNILSIG

PF15917 // ENSGT00390000013029_1_Domain_0 (1492, 1775)

ACGYIGTLV
HNSCWLIQAFSLACTVKGYQ--------MPAANSPCTLPSGEAGIIWDSICFAFLLLQRR
VFMSYYFLHVVA--------DIKASQILASRGAELFQATIVKAVKARIEEEKKSMDQLKR
QMDRIKARQQKYKKGKERMLSLTQEPGEGQDMQKLSEEDDE-READKQKAKGKKKQWWRP
WVDHASMVRSGDYYLFETDSEEEEEEELKKEDEEPPRRSAF-------------------
--------------QFVYQAWITDPKTALRQRHK

ENSGT00390000013029_1_Linker_0_3 (1775, 2665)

EKKRSAREERKRRRKGSKEGP--VEW
EDREDEPIKKKSDGPDNIIKRIFNILKFTWVLFLATVDSFTTWLNSISREHIDISTVLRI
ERCMLTREIKKGN-VPTRESI-HMYYQNHI-MNLSRESGLDTIDERPGAASGAQTAHRMD
SLD---SHDSIS------------------------------------------------
--------SEPTQCTMLYSRQGTTETIEEVEAEQEEEAGSTVPEPSEAKEYE--------
-------AAGYDVGAVGAEEASLTPE---EELTQFSTLDGDVEAPPSYSKAVSFEHLSFG
SQDD-SAGKNHMAVSPDDSRTD-----KLGSSILPPLTHELTASELLLNKMFHDDE--LE
ESEKFYVGQPRFLLLFYAMYNTLVARSEMVCYFVIILNHMVSASMITLLLPILIFLWAML
SVPRPSRRFWMMAIVYTEVAIVVKYFFQFGFFPWNKNAEV--NKDKPFHPPNIIGVEKKE
GYVLYDLIQLLALFFHRS--ILKCHGLWDEDDMTESGMDKEESDDEL---SLGHGRRDSS
---DSLKSINLAASVES-----------------VHVTFPEQQTAVRRKR--SSSNSEPS
QRSSFSSNRSQR-----GST-STRNSSQKG--SSVLSIK-----QKSKRELY-MEKLQEH
LIKAKAF----------------TIKKTLQIYVPIKQFFYNLIHPDYSAVTDVYVLMFLA
DTVDFIIIVFGFWAFGK-HSAAADITSSLSEDQVPGPFLVMVLIQFGTMVVDRALYLRKT
VLGKVIFQVILVFGIHFWMFFILPGVTERKFSQNLVAQLWYFVKCVYFGLSAYQIRCGYP
TRVLGNFLTKSYNYVNLFLFQGFR

PF12166 // ENSGT00390000013029_1_Domain_3 (2665, 3094)

LVPFLTELRAVMDWVWTDTTLSLSSWICVEDIYAHI
FILKCWRESEKRYPQPRGQKKKKVVKYGMGGMIIVLLICIVWFPLLFMSLIKSVAGVINQ
PLDVSVTITLGGYQPIFTMSAQQSQLKVMDQQNFNKFIQA-----FSRDTGAMQFLENYE
KEDITVAELEGNSNSLWTISPPSKQKMIHELLDPNSSFSVVFSWSIQRNLSLGAKSEIAT
DKLSFPLKNITRKNIAKMIAGNSTESSKTPVTIEKIYPYYVKAPSDSNSKPIKQLLS--E
NNFMDITI-------------ILSRDNTTKFNSEWWVLNLTGNRIYNPNSQALELVVFND
KVSPPSLGFLAGYGIMGLYASVVLVIGKFVREFFSGISHSIMFEELPNVDRILKLCTDIF
LVRETGELELEEDLYAKLIFLYRSPETMIKWTREKTN

------------------------------------------------------------
------------------------------------------------------------
------FSLLSFCSLKGADAGNGIRVFVPDIGMFIASLTTWLVCRNIVQKPVPEDAAQYN
MQFENEEMAGREKADSEEALIYE-EDLDAGDAIEGELEESTKLKILRRFASLASRLKEFI
GNMIATAGKVVVTILLGS-TGMMLPSLTSLVYFFVFLGLCTWWSWCRTFDPLIFSCLCVL
MAIFSAGHLIGLYLYQFQFFQEAVPPGDYYA-RLFGITSVIQTNCSSTWKIIVHPKLSWY
HHANPILLLVTYYTLATLI-RLWLQEPI--VQDDETN------DEDKDMPCSPVQI-TAE
RRRSLWYATHYPTDERKLLSMTQDDYKPSDVLLVTVNGAPVDYHTIHPSLPIENGPAKTD
MYSTPYWPCQKDETLREKKEE----E-EEEEENRSQEEKPNIKVHAMVSVFQFIMKQSYI
CALIAMM-AWSITYHSWLTFVLLIWSCTLWMIRNRRKYAMISSPFMVVYGNLLLTLQYIW
SFDLE--EIKEVPGFLEKKAPGELAS---------KILFTITFWLLLRQHLTEQKALQLK
EALLSEVKIGSQEDEEK----EDDELQDIEV---EGEPKEKEQ-----------------
-----------DKGKIKKQESKKEEEDHDEDDDDQDIMKVMGNLVMAMFIKYWIYVCGGM
FFFVSFEGRIVMYKIIYMVLFLFCVALYQVHYEWWRKILKYFWMSVVIYTMLVLIFIYTY
QFENFPGLWENMTGLNKEKLEDLGLKKFTITELFTRIFIPTSFLLVCILHLHYFHDRFLE
LTDLKSIPSKEDNTIYSHAKVNGRVYLIIN-----------RLANPEGSLPDLAMMNLTA
SMEKEAMRRLEEDGQEKTEEYYEEEEKG--GDRKDSEDEEEED------EDGEEESEEEE
ETSDIRNKWHLVIDRLTVLFLKFLEYFHKLQVFMWWILELHIIKIVSSYIIWVT-VK-EV
SLFNYVFLISWAFALPYAQLRRLASSICTVWTCVIIVCKMLYQLSTIDPVKFSVNCTWPN
QNETNIN-ITYLNT-SMLYSGPIDPAEWVGLRKSFPLLVYLRNNLLMLAILAFEVTIYRH
QEYYRCRNNLTAPVSKTIFHDITRMHLDNGLINCAKYFINYFFYKFGLETCFLMSVNVIG
QRMDFYAMIHACWLIAVLYRRRRKAIAEIWPKYCCFLACIITFQYFVCIGIPPAPCRDYP
WRYPGASFDNNIIKWLYFPDFIVRPNPVFLVYDFMLLLCASLQRQTFEDENKAAVRIMAG
DNVEICMSLDAASFSQHNPVPDFIHC-RSYLDMYKVIIFSYLFWFVLTIIFITGTTRISL
FCMGYLVACFYFLLFGGDLLLKPIKSILRCWDWLIAYNVFVITMKNILSIGACGYIESLV
QKNCWLIQAFSLACTVKGYK--------MPLDNKECKLPSGEAGIIWDSICFAFLLLQRR
VFMSYYFLHVVA--------DIKASQILASRGAELFQATIVKAVKARMEEEKKSMDQLKR
QMDRIKARQQKYKKGKERMLSLTQESGEGQSLQRVSEEDDE-READKQKAKGKKKQWWRP
WVDHASMVRSGDYYLFETDSEEEEEEEEK-KDEEPPKKSAF-------------------
--------------QFVYQAWITDPKTALRQRRKEKKRSAREEQKRRRKGSGEGP--VEW
EDREDEPLKKKSDGPDNIIKRIFNILKFTWVLFLASVDSFTTWLNSISREHIDISTVLRI
ERCMLTREIKKGN-VPTRESI-HMYYQNHI-MNLSRESGLDTIDENPGASSSLKTAQRMD
SLD---SHDSISSCYTEATLLFSRQSTLDDLDGRETIPKTSERARPRLRKMYSMDMSSSS
ADSGSLASSEPTQCTLLYSRQGTTETIEEVEAEQEEEVVGPLPELKDEEDDEY-------
-------DEDSVEVDLT-SDAELPQYSTMETVDTIDTVDGDVEAPPSYSKAVSFERLSFG
SHD-ASDDKNHMVVSPDDSRTD-----KSEISIPLPLTHELTASELLLNKMFHDEE--LE
ESEKFYVDQPRFLLLFYALYNTLVARSEMVCYFVIILNHMISASMITLVLPILIFLWAML
SVPRPSRRFWMTAIVYTEVAIVIKYFFQFGFFPWNKNLDF--YKDKPYHPPNIIGVEKKE
GYVLYDLIQLLALFFHRS--ILKCHGLWDEDDTVDTGTNKDDSDDEL---SLNTGRRDSS
---DSLKSINLAASVES-----------------VHVHFPEQQAAIRRKS--SSSNSHLS
HRSSFSSNRSKR-----GST-STRNSSQKG--SSVLSIK-----QKSKKELY-MEKFQEH
VIKAKAF----------------TIKKTLQIYVPIRQFFYNLIHPDYSAVTDVYVLMFLA
DTVDFIIIVFGFWAFGK-HSAAADITSSLSEDQVPEAFLVMVLIQFGTMVVDRALYLRKT
VLGKVIFQVILVFGIHFWMFFILPGVTERKFSQNLVAQLWYFVKCVYFGLSAYQIRCGYP
TRVLGNFLTKSYNYVNLFLFQGF

PF12166 // ENSGT00390000013029_1_Domain_3 (2664, 3014)

RLVPFLTELRAVMDWVWTDTTLSLSSWICVEDIYAHI
FILKCWRESEKRYPQPRGQKKKKVVKYGMGGMIIVLLICIVWFPLLFMSLIKSVAGVINQ
PLDVSVKITLGGYQPIFTMSAQQSQLKLMEPALFKSFLRN-----YSTNTNAMQFLENYQ
REDITVVELEGNSNSLWTISPPSKLKMIKELKDFDNSFSLVFSWSIQRNLSLGAKAEIAS
DKISFKLENDTRTSIANMMSGNKT--TVTPATIKGIYPYYLKAPSDANTKPIKQLLK--D
NNFKDITI-------------ILSRDNNSITENEWWVLNQLGNKLHNKNNQGLELVVFND
KVSPPSLGFLAGYG----------------------------------------------
-------------------------------------

--------------------------------------KLSKC-----QLVLLF------
----------SKCRLSENMCFILYKELSQ-TLFHIY----YLSSLE--------------
-------QNKEGKYLKGADAGNGIRVFVPDIGMFIASLTIWLLCRNIVQKPVTDEAAQSN
LEFENEELAGGEKIDSEEALIYE-EDLDGGDGVEGELEESTRLKMFRRLACVASKLKEFI
GNMITTAGKVVVTILLGS-SGMMLPSLTSSVYFFVFLGLCTWWSWCRTFDPLLFSCLCVL
LAIFTAGHLIGLYLYQFQFFQEAVPPSDYYA-RLFGIKSVIQTDCSSTWKIIVNPDLSWY
HHANPILLLVMYYTLATLI-RIWLQEPL--VQEERTK------EEDKALACSPIQI-TAE
RRRSLWYATHYPTDERKVSLS----LHSRQGLLVTVNGNPVDYHTIHPSLPMENGPGKAD
LYSTPQYRWEPSDESSEKREE-EEEEKEEFEEERSREEKRSIKVHAMVSVFQFIMKQSYI
CALIAMM-AWSITYHSWLTFVLLIWSCTLWMIRNRRKYAMISSPFMVVYGNLLLILQYIW
SFELP--EIKKVPGFLEKKEPGELAS---------KILFTITFWLLLRQHLTEQKALREK
EALLSEVKIGSQENEEK-----GKLVY---------------------------------
----------MACEKQERKKVEEEE---VEEEDEQDIMKVLGNLVVAMFIKYWIYVCGGM
FFFVSFEGKIVMYKIIYMVLFLFCVALYQVHYEWWRKILKYFWMSVVIYTMLVLIFIYTY
QFENFPGLWQNMTGLKKEKLEDLGLKQFTVAELFTRIFIPTSFLLVCILHLHYFHDRFLE
LTDLKSIPSKEDNTIYRQPSTLPE------------LLSANRLAHPEGSLPDLTMMHLTA
KLEKPEVRKLAEPGEEKPEGYSEKSS--CF------------------------------
------------VD---VLFV--------MPCYV----------FLSP--FLVVCFQ--V
SLFNYVFLISWAFALPYAKLRRLASSVCTVWTCVIIVCKMLYQLQTIKPENFSVNCSLPN
ENQTNIP-LNELNKSLLYSAP-VDPTEWVGLRKSSPLLVYLRNNLLMLAILAFEVTIYRH
QEYYRGRNNLTAPVSKTIFHDITRLHLDDGLINCAKYFINYFFYKFGLETCFLMSVNVIG
QRMDFYAMIHACWLIAVLYRRRRKAIAEIWPKYCCFLACIITFQYFICIGIPPAPCRDYP
WRFKGASFNDNIIKWLYFPDFIVRPNPVFLVYDFMLLLCASLQRQIFEDENKAAVRIMAG
DNVEICMNLDAASFSQHNPVPDFIHC-RSYLDMSKVIVFSYLFWFVLTIIFITGTTRISI
FCMGYLVACFYFLLFGGDLLLKPIKSILRYWDWLIAYNVFVITMKNILSVSGSHCITHFP
CKTQC-LS

PF15917 // ENSGT00390000013029_1_Domain_0 (1509, 1775)

CCSLKNAANSEL--------KTAANSPCTLPSGEAGIIWDSICFAFLLLQRR
VFMSYYFLHVVA--------DIKASQILASRGAELFQATIVKAVKARIEEEKKSMDQLKR
QMDRIKARQQKYKKGKERMLSLTQEPGEGQDMQKLSEEDDE-READKQKAKGKKKQWWRP
WVDHASMVRSGDYYLFETDSEEEEEEELKKEDEEPPRRSAF-------------------
--------------QFVYQAWITDPKTALRQRHK

ENSGT00390000013029_1_Linker_0_3 (1775, 2665)

EKKRSAREERKRRRKGSKEGP--VDW
EDREDEPIKKKSDGPDNIIKRIFNILKFTWVLFLATVDSFTTWLNSISREHIDISTVLRI
ERCMLTREIKKGN-VPTRESI-HMYYQNHI-MNLSRESGLDTIDERPGAASGAQTAHRMD
SLD---SHDSIS------------------------------------------------
--------SEPTQCTMLYSRQGTTETIEEVEAEQEEEAGSTVPEPREAKEYE--------
-------AAGYDVGAVGAEEASLTPE---EELTQFSTLDGDVEAPPSYSKAVSFEHLSFG
SQDD-SAGKNHMAVSPDDSRTD-----KLGSSILPPLTHELTASELLLNKMFHDDE--LE
ESEKFYVGQPRFLLLFYAMYNTLVARSEMVCYFVIILNHMVSASMITLLLPILIFLWAML
SVPRPSRRFWMMAIVYTEVAIVVKYFFQFGFFPWNKNAEV--NKDKPFHPPNIIGVEKKE
GYVLYDLIQLLALFFHRS--ILKCHGLWDEDDMTESGMDKEESDDEL---SLGHGRRDSS
---DSLKSINLAASVES-----------------VHVTFPEQQTAVRRKR--SSSNSEPS
QRSSFSSNRSQR-----GST-STRNSSQKG--SSVLSIK-----QKSKRELY-MEKLQEH
LIKAKAF----------------TIKKTLQIYVPIKQFFYNLIHPDYSAVTDVYVLMFLA
DTVDFIIIVFGFWAFGK-HSAAADITSSLSEDQVPGPFLVMVLIQFGTMVVDRALYLRKT
VLGKVIFQVILVFGIHFWMFFILPGVTERKFSQNLVAQLWYFVKCVYFGLSAYQIRCGYP
TRVLGNFLTKSYNYVNLFLFQGFR

PF12166 // ENSGT00390000013029_1_Domain_3 (2665, 3094)

LVPFLTELRAVMDWVWTDTTLSLSSWICVEDIYAHI
FILKCWRESEKRYPQPRGQKKKKVVKYGMGGMIIVLLICIVWFPLLFMSLIKSVAGVINQ
PLDVSVTITLGGYQPIFTMSAQQSQLKVMDQQNFNKFIQA-----FSRDTGAMQFLENYE
KEDITVAELEGNSNSLWTISPPSKQKMIHELLDPNSSFSVVFSWSIQRNLSLGAKSEIAT
DKLSFPLKNITRKNIAKMIAGNSTESSKTPVTIEKIYPYYVKAPSDSNSKPIKQLLS--E
NNFMDITI-------------ILSRDNTTKFNSEWWVLNLTGNRIYNPNSQALELVVFND
KVSPPSLGFLAGYGIMGLYASVVLVIGKFVREFFSGISHSIMFEELPNVDRILKLCTDIF
LVRETGELELEEDLYAKLIFLYRSPETMIKWTREKTN

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-----------------------------------------------------MEKLQEH
LIKAKAF----------------TIKKTLQIYVPIRQFFYDLIHPDYSAVTDVYVLMFLA
DTVDFIIIVFGFWAFGK-HSAAADITSSLSEDQVPGPFLVMVLIQFGTMVVDRALYLRKT
VLGKVIFQVILVFGIHFWMFFILPGVTERKFSQNLVAQLWYFVKCVYFGLSAYQIRCGYP
TRVLGNFLTKSYNYVNLFLFQGFR

PF12166 // ENSGT00390000013029_1_Domain_3 (2665, 3094)

LVPFLTELRAVMDWVWTDTTLSLSSWICVEDIYAHI
FILKCWRESEKRYPQPRGQKKKKVVKYGMGGMIIVLLICIVWFPLLFMSLIKSVAGVINQ
PLDVSVTITLGGYQPIFTMSAQQSQLKVMDQQKVLSL----------GPTGAMQFLENYE
KEDITVAELEGNSNSLWTISPPSKQKMIQELMDPNSSFSVVVSWSIQRNMSLGAKSEIAT
DKLSFSLQNITRENIAKMIAGNDTQSSNTPVTIEKIYPYYVKAPSDSNSKPIKQLLS--E
NNFMNITI-------------ILSRDNMSKSNSEWWVLNLTGNRIYEQNSQALELVVFND
KVSPPSLGFLAGYGIMGLYASVVLVIGKFVREFFSGISHSIMFEELPNVDRILKLCTDIF
LVRETGELELEEDLYAKLIFLYRSPETMIKWTREKTN

------------------------------------------------------------
------------------------------------------------------------
-------------SVKGADAGNVIRVFVPDIGMFIASLTIWLVCRNLVLKPVTEDAAQYN
TQFENEEMVGREKLEPDDALIYE-EDLDGGEYSEEEFEETTKLKLLRRIASLASKLKEFI
GNIITTAGKVVVIILIGSTAGMMLPSLTSAVYFFVFLGLCTWWSCCLAFDPLIFSCLCVL
MAIYSAGHLIGLYLYQLQFFQEVVPPKDFYA-RLFGVTSVIQTNCSSTWKIIANQDLLWY
HHANPILLLVMYYTLATLI-RLWLQEPI--VRGMDDEGKSESREEEKET-DCNA----TS
PRRSLWYASHYTPDETKLLSMTQDEYKPSDVLLVTVNGTPVDYHTIHPTLHLENGPAKAD
MYSTPQYKWEPSDDMSEKKEE-EDEE--EEEEEDIQEEKENVKIHAMVSVFHFIMKQSYI
CALIAMM-AWSITYHSWLTFVLLIWSCTLWMIRDRRKYAMISSPFMVVYGNLLLTLQYIW
SIDLDNDELPKVSGFLEKKDPGELAS---------KILFTITFWLLLRQHLTERKVLQQK
EATLAEVKVGDEENEEK----GHSAPVEVQALRFFGRVNRA--EEELQ------------
--------------------EEVTEEADEEEEDEQDIMKVLGNLVMAMFIKYWIYVCGGM
FFFVSFEGRIVMYKIIYMMLFLFCVALYQVHYEWWRRILKYFWMSVVVYTMLVLIFIYTY
QFESFPGLWMNMTGLDEKKLEDLGLKRFSVAELFTRIFIPTSFLLVCILHLHYFHDRFLQ
LTDLKAVTSKQDSTIYSHAKVNGRVYLIIN-----------RLVHQDGSLPDITMMNLTA
SNEKEEDKKLDDDGNESMEERNGEGEKDGDEKEKEKEQ------------EEEEEEEEEF
VFADLRNKWHLVIDRLTVLFLKFLEYFHKMQVFVWWLLELHIIKIVSSYIIWVTVKE--V
SLFNFVFLIAWALALPYAQFRPLASSVCTVWTCVIIVCKMLYQLTSIDPSTFSSNCTMPT
ENETNIG-NEELKTSLLYSAP-IDPTEWVGLRKSYPLLVYLRNNLLMLALLAFEVTIYRH
QEYYRCRNNLTAPVTKTIFHEITRLHLDDGLVNCAKYFINYFFYKFGLETCFLLSVNVIG
QRMDFYAMIHAFWLIAVLYRRRRKAIAEIWPKYCCFLACIIIFQYFICIGIPPAPCKDYP
WRSPNANFNSNIIKWLYFPDFIERPNPIFLVYDFMLLLCASLQRQMFEDENKAAVRIMAG
DNVEICMNLDAASFSQHNPVPDFIHC-RSYLDMYKVIIFSYLFWFVLTIIFITGTTRISI
FCMGYLVACFYFLLFGGDLLLKPIRSILRYWDWLIAYNVFVITMKNILSIGACGYIEPLI
KNSCWLIQAFSLACTVKGYRFPK--------ETGDCKLPSGEAGIIWDSICFAFLLLQRR
VFMSYYFLHVVA--------DIKASQILASRGAELFQATIVKAVKARIEEEKKSMDQLKR
QMDRIKARQQKYKKGKERMLSMNQESTEGQEVQKVSEEDDE-GEADKEKTKGKKKLWWRP
WVDHASMVRSGDYYLFETDSEEEEEDE-KKDEEEPRRRSAF-------------------
--------------QFVYQAWITDPKTALRQRRKEKKKFGKEDKQRRKGSGDGAID-VEY
EEKEEEAVKKKSDGPDNIIKRIFNILKFTWVLFLATLDSFTAWLNSISREHIDISTVLRI
ERCMLTREIKKGN-VPTRESI-HMYYQNHM-MKLSKESGLDTIDENPGQASSLQASERMD
SLDSAVSHDSISSCYTEATMLFSRQSTLDDLDGPDTVPKTSERARPRLRKMYSMDMSSSS
ADSGSIVSSEPTQVTLLYSRQGTTETIEEVEGEHEEEEPDSTSRR-DDE-AE--------
-----DYGLDSE-------D-AV--YTPDTDMPSYSAVDGNAEVPPSYSKAVSFERLSFS
-SQDDSAGKSLMMVSPDDSRID-----KLNDTLLPPLTHDLTASELLLNKMFHDEE--LE
ESEKFYIGQPRVLLLVYALYNTLVARSEMVCYFVIILNHMISASMITLVLPILIFLWAML
SVPRPSKRFWMTAIVYTEVTIVIKYFFQFGFFPWNKHVDY--TKDKPYHPPNIIGIEKKE
GYVHYDLVQLLALFFHRS--ILKCHGLWDEDDEGESCSSKEEYGDEL---SLTGGRRDSA
---DSLKSVNLAASVES-----------------IHVHFPEQQTAIRRKS--SSSGSQLS
HRSSFSSQRSKR-----GST-STRNSSQKG--SSVLSIK-----QKSRKELL-MEKFREQ
MIKAKAFTIKK----------------TLQIYVPIRQFFYNLIHPEYSAVTDVYVLMFLA
DTVDFIIIVFGFWAFGK-HSAAADITSSLSEDQVPEAFLVMVLIQFGTMVVDRALYLRKT
VMGKVIFQVILVFGIHFWMFFILPGVTERKFSQNTVAQLWYFVKCVYFGLSAYQIRCGYP
TRVLGNFLTKSYNYVNLFLFQGF

PF12166 // ENSGT00390000013029_1_Domain_3 (2664, 3095)

RLVPFLTELRAVMDWVWTDTTLSLSSWICVEDIYAHI
FILKCWRESEKRYPQPRGQKKKKVVKYGMGGMIVVLLICIVWFPLLFMSLVKSVAGVTNK
PLDVSITITLGGYQPIFTMSAQQNQLKDLNQTEFDSFQKE-----YSGNTAALQFLEGYG
KEDITVAELEGNSNSLWTISPPSRKKMIQGLRDFSAEFTLVLSWTIQRNLSLGAKIEIAS
DKLSCNLPNKTRENIATMMSGDHKVKKVCPRNLEMIFPYYIKAPSDSLAKPIKHLW--KD
GRMENITV-------------SLVKNESKDGVREWWVLNQLGKR-YR-QEESLELFVFSD
KVSPPSLGFLAGYGIMGLYASVVLVIGKFVREFFSGISHSIMFEELPNVDRILKLCTDIF
LVRETGELELEEDLYAKLIFLYRSPETMIKWTREKTN

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-----------------------------------------------------MEKLQEH
LIKAKAF----------------TIKKTLQIYVPIRQFFYNLIHPDYSAVTDVYVLMFLA
DTVDFVIIVFGFWAFGK-HSAAADITSSLSEDQVPGPFLVMVLIQFGTMVVDRALYLRKT
VLGKVIFQVILVFGIHFWMFFILPGVTERKFSQNLVAQLWYFVKCVYFGLSAYQIRCGYP
TRVLGNFLTKSYNYVNLFLFQGF

PF12166 // ENSGT00390000013029_1_Domain_2 (2664, 2711)

RLVPFLTELRAVMDWVWTDTTLSLSSWICVEDIYAHI
FILKCWRESE

ENSGT00390000013029_1_Linker_2_3 (2711, 2774)

K-------------------------------------------------
-------------

PF12166 // ENSGT00390000013029_1_Domain_3 (2774, 3095)

-PIFTMSAQQSQLKVMDQPKFNKFIKA-----FSRDTGAMQFLENYE
KEDITVAELEGNSNSLWTISPPSKQKMIHELTDPNSSFSVVFSWSIQRNMSLGAKAEIAT
DKLSFPLKNTTRENIAKMIAGNNTESSKTPVTIEKIYPYYVKAPSDSNSKPIKQLLS--E
NNFMNITI-------------ILSRDTSTKSNSEWWVLNLTGNRIYNQHAQALELVVFND
KVSPPSLGFLAGYGIMGLYASVVLVIGKFVREFFSGISHSIMFEELPNVDRILKLCTDIF
LVRETGELELEEDLYAKLIFLYRSPETMIKWTREKTN

----------MASEVVCGLIFRLLLPICLAVACAFRYNGLSFVYLIYLLLIPLFSEPTKA
T------MQGHTGRLLKSLCFISFSFLLLHIIFHIT-----LASLEAQHHTAASYNCSTW
EKTFRQIGFE---SLKGADVGNGIRVFVPDIGMFIASLTIWLVCRNIVQKPVGEEAAQYN
PEFENEESAGGEKIDSEEALVYE-EDLDEGDGVDGRLEESTKLKLFRRLASVASKLKEFI
GNMITTAGKVVVTILLGS-SGMMLPSLTSSVYFFVFLGLCTWWSWCRTFDPLLFSCLCVL
LAIFTAGHLIGLYLYQFQFFQEAVPPDDYYA-RLFGIKSVIQIDCSSTWKIIANPDLSWY
HHANPILLLVMYYTLATLI-RIWLQEPL--VQDERTK------EEDRALACSPVPI-TAE
RRRSLWYATHYPTDERKLLSMTQDDYKPSDGLLVTVNGNPVDYHTIHPSLPLENGPAKAD
LYSTPQYRWEPPEDSSEE------EEREEFEEERSHEEKRSVKVHAMVSVFQFIMKQSYI
CALIAMM-AWSITYHSWLTFVLLIWSCTLWMIRNRRKYAMISSPFMVIYGNLLLVLQYIW
SFELP--EIKKVPGFLEKKEPGELAS---------KILFTITFWLLLRQHLTEQKALQEK
EALLSEVKIGSQEDEEK----DD--DQDVHVD---GEAPEKEDEEMTK------------
----------------EE---KQELEEEEEEEDDQDVMKVLGNLVVALFIKYWIYVCGGM
FFFVSFEGKIVMYKIIYMVLFLFCVALYQVHYEWWRRILKYFWMSVVIYTMLVLIFIYTY
QFENFPGLWQNMTGLKKEKLEDLGLKQFTVAELFTRIFIPTSFLLVCILHLHYFHDRFLE
LTDLKSIPSKEDSTIYSHAKVNGRVYLII-----------NRLAHPEGSLPDLAMMNLTT
TLEASEAKQLAGPEEEKPGGCLAKAKKGELSR--DSE-----DE--------EEEEDEEE
ETSDLRNKWHLVMDRLTVLLLKFLECFHRLQTFLWWVLELHVIKVVSSYIIWVSV--KEV
SLFNYVFLISWAFALPYAKLRRLASSVCTVWTCVIIVCKMLYQLQTIKPENFSVNCSLPN
ENQTNIPL-HQLNKSLLYSAP-IDPTEWVGLRKSAPLLVYLRNNLLMLAIL---------
-EYYRGRNNLTAPVSKTIFHDITRLHLDDGLVNCAKYFINYFFYKFGLETCFLMSVNVIG
QRMDFYAMIHACWLIAVLYRRRRKAIAEIWPKYCCFLACILSFQYLICIGFPPAPCRDYP
WRFKGASFNDNIVKWLYFPDFIVRPNPVFLVYDFMLLLCASLQRQIFEDENKAAVRIMAG
DNVEICMNLDAASFSQHNPVPDFIHC-RSYLDMSKVIIFSYLFWFVLTIIFITGTTRISI
FCMGYLVACFYFLLFGGDLLLKPIKSILRYWDWLIAYNVFVITMKNILSIG

PF15917 // ENSGT00390000013029_1_Domain_1 (1492, 1588)

ACGYIEKLV
QNSCWLIQAFSLACTVKGYKMPD--------DDSSCKLPSGEAGIIWDSICFAFLLLQRR
VFMSYYFLHVVA--------DIKASQIL----GLNFSRPLL-------------------
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--------------------CFDFCL---------QILFTITFWLLLRQHLTEQKALRLK
EATLSEVKVGSEEN----------------------------------------------
-------------------------------EDEQDIMKVLGKLVMAMLIKYWIYVCGGM
FFFVSFEGTIVMYKIIYMVLFLFCVALYQVHYEWWRKILKYFWMSVVVYTMLVLIFIYTY
QFESFPGLWKNMTGLDERKLEDLGLKQFSVADLFTRIFIPTSFLLVCILHLHYFHDRFLQ
ITDLKAVTSKQDNTIYSSLFLSVPITLS----------------------------SLK-
-------KKI-----------------PNHQNEKEEEKEDEDKEED-DDDDNEDNESEEE
ETTDLRNKWHLVIDRLTVLFLKFLEYFHKMQVFVWWLLELHIIKIVSSYIIWVTVKE--V
SLLNFVFLIAWALALPYAQFRPLASSICTVWTCVIIVCKMLYQLTSIDPKDFSRNCTLPG
ENETKVN-LEELKTSVLYSGP-VDPSEWVGLRKSSPLLVYLRNNLLMLAILAFEVTIYRH
QEYYRCRNNLTAPVTKTIFHDITRAHLDDGLVNCVKYFINYFFYKFGLETCFLLSVNVIG
QRMDFYAMIHAFWLIAVLYRRRRKAIAEIWPKYCCFLTCIITFQYFLCIGIPPAPCKDYP
WRSGNANFNSNIIKWLYFPDFIVRPNPVFLVYDFMLLLCASLQRQTFEDENKAAVRIMAG
DNVEICMNLDAASFSQHNPVPDFIHC-RSYLDMYKVIIFSYLFWFVLTIIFITGTTRISI
FCMGYLVACFYFLLFGGDLLLKPIRSILRYWDWLIAYNVFVITMKNILSIGACGYIESLI
EKSCWVIQAFSLACTVKGYHIRKY----TSTSNPDCKLPSGEAGIIWDSICFAFLLLQRR
VFMSYYFLHVVA--------DIKASQILASRGAELFQATIVKAVKARIEEEKKSMDQLKR
QMDRIKARQQKYKKGKERMLSMNQESSEGPEIRKVSE---E-GDADKEKAKGKKKLWWRP
WVDHASMVRSGNYYLFETDSEEEEEEE-KKEEEEPRKKSAF-------------------
--------------QFVYQAWITDPKTALRQRRKEKKSFGKEKRRRKESVDGGGND-ADC
EDSEEEPVKKKSDGPDNIIKRIFNILKFTWVLFLATLDSFTAWLNSISREHIDISTVLRI
ERCMLTREIKK-------------------------------------------------
------------------------------------------------------------
--------------------------------------------------VE--------
-----DYSLDSE-------G-AA--YTPDTDAPLYSTVDSNAEAPPSYSKAVSFEHLPFG
-SPDDSAGKSLMMVSPDDSRTD-----KL-DRILPPLTHELTASELLLNKMFHDDE--LE
ESEKFYVGQPRVLLLIYALYNTLVARSEMVCYFVIILNHMISASMITLVLPILIFLWAML
SVPRPSKRFWMTAIVYTEVAIVIKYFFQFGFFPWNKHVDY--TKDKPYHPPNIIGIEKKE
GYVHYDLVQLLALFFHRS--ILKCHGLWDEDEKGDSSSNKEDTDDEL---SLTGGRRDSS
---ASLKSVNLAASVES-----------------IHVHFPEQQTAIRRKS--SSSISQLS
HRSSFSSHRSKR-----GST-STRNSSQKG--SSVLSIK-----QKSRKELL-MEKFREQ
IIKAKAFTIKNA----IKSHCDLYCFRTLQVYMPIRQFFYNLIHPDYSAVTDVYVLMFLA
DTVDFIIIVFGFWAFGK-HSAAADITSSLSEDQVPEAFLVMVLIQFGTMVVDRALYLKKT
VMGKVIFQVILVFGIHFWMFFILPGVTERKFSQNTVAQLWYFVKCVYFGLSAYQIRCGYP
TRVLGNFLTKSYNYVNLFLFQGF

PF12166 // ENSGT00390000013029_1_Domain_3 (2664, 3095)

RLVPFLTELRAVMDWVWTDTTLSLSSWICVEDIYAHI
FILKCWRESEKRYPQPRGQKKKKVVKYGMGGMIIVLLICIVWFPLLFMSLIKSVAGITNK
PLDVSITITLGGYQPIFTMSAQQNQLKSLDPNEFNNITALNFSFLLLHLQAALQFLEGYA
REDITRADLEGNSNSLWTISPPSRQKMIQGLQDFEADFTLVISWTIQRNLSLGAKAEIAS
DKLTFPLKNHTRRDIATMMAENQP----EKVTLEEVYPYYIEDPSDSLAKPIKADIERID
CKWENITV-------------SLVKNAS----EEWWVLNQLGKR-QKTPQESLELFIFSD
KVSPPSLGFLAGYGIMGLYASVVLVIGKFVREFFSGISHSIMFEELPNVDRILKLCTDIF
LVRETGELELEEDLYAKLIFLYRSPETMIKWTREKTN

---------------EC-ATFVMGIPFREGCSCAFRYNGLSFVYLIYLLLIPLFSEPTKA
T------MQGHTGRLLKSLCFTSLSFLLLHIIFHIT-----LASLEAQHRIAPSYNCSTW
EKTFRQIGFE---SLKGADAGNGIRVFVPDIGMFIASLTIWLVCRNMVQKPAQEETVQDS
LEFESEELARGEKMDSKEALIDEDKDLDGGDGEDVELEDSARLKLFRQLASVASRLKEFV
GNMITTAGKVVVTILLGS-SGMMLPSLTSAVYFLVFLGLCTWWSWCRTFDPLLFSCLCVL
LAIFTAGHLIGLYLYQFQFFQEAVPPNDYYA-RLFGIKSVIQTDCSNTWKIIVNPDLSWY
HHANPILLLVMYYTLATLI-RIWLQEPL--VPDEPAKE------EDHALGDSPKQHYSAE
RRRSLWYAAHYPTDERKLLSMTQDDYKPSDGLLVTVNGNPVDYHTIHPSLPLENGPAKPD
LYSTPRYRWEPSEESAEKKED-EEGEKEEFEEERSQDDRRSVRVHAMVSVFHFIMKQSYI
CALIAMM-AWSITYHSWLTFVLLIWSCTLWMIRNRRKYAMISSPFMVVYANLLLVLQYIW
SFELP--EIKKVPGFLEKKEPGELAS---------KILFTITFWLLLRQHLTEQKALREK
EALLAEVKIGSQEHEEK-----DEELQDVQVE---GEPREKKEEEGAKEEKPE-------
-------------------RRKEEE-EAEEEEDDQDIMKVLGNLVVAMFIKYWIYVCGGM
FFFVSFEGKIVMYKIIYMVLFLFCVALYQVHYEWWRKILKYFWMSVVIYTMLVLIFIYTY
QFENFPGLWQNMTGLKKEKLEDLGLKQFTVAELFTRIFIPTSFLLVCILHLHYFHDRFLE
LTDLKSIPSKEDSAIYSHAKVNGRVYLIIN-----------RLAHPEGSLPDLAMMHLTP
SLDKPEPKKLAEPGQEKPEGRGKTERALKGES--ETDSQDEDEE----------ESEEEE
DMSDLRNKWHLVIDRLTVLFLKFLEYFHKLQVFMWWLLELHIIKVVSSYIIWVSVKE--V
SLFNYVFLISWAFALPYAKLRRLASSVCTVWTCVIIVCKMLYQLQTIKPSNFSINCSLPN
ESQTNIP-LSELNKSLLYSAP-IDPTEWVGLRKSSPLLVYLRNNLLMLAILAFEVTIYRH
QEYYRGRNNLTAPVSKTIFHDITRLHLDDGLVNCAKYFVNYFFYKFGLETCFLMSVNVIG
QRMDFYAMIHACWLIGVLYRRRRKAIAEVWPKYCCFLACILTLQYLVCIGVPPAPCRDYP
WRLKGANFNDNIIKWLYFPDFIMRPNPVFLVYDFMLLLCASLQRQIFEDENKAAVRIMAG
DNVEICMNLDAASFSQHNPVPDFIHC-RSYLDMSKVVIFSYLFWFVLTIIFITGTTRISI
FCMGYLVACFYFLLFGGDLLLKPIRSILRYWDWLIAYNIFVITMKNILSIG

PF15917 // ENSGT00390000013029_1_Domain_0 (1492, 1775)

ACGYIGTLV
KNSCWLIQAFSLACTVKGYKM--------PSDDSNCRLPSGEAGIIWDSICFAFLLLQRR
VFMSYYFLHVVA--------DIKASQILASRGAELFQATIVKAVKARIEEEKKSMDQLKR
QMDRIKARQQKYKKGKERMLSLTQESGEGQDAQKLSEEDDE-READKQKAKGKKKQWWRP
WVDHASMVRSGDYYLFETDSEEEEEEELKKEDEEPPRKSAF-------------------
--------------QFVYQAWITDPKTALRQRRK

ENSGT00390000013029_1_Linker_0_3 (1775, 2665)

EKKKSAREEQKRKRRGSGQGP--VEW
EDREEEPVKKKSDGPDNIIKRIFNIVKFTWVLFLATVDSFTTWLNSISREHIDISTVLRI
ERCMLTREIKKGN-VPTRESI-HMYYQNHI-MNLSRESGLDTIEEGPRAGPRAPAAHRMD
SLD---SHDSISSCYTEATMLFSRQSTLDDLDGPDPVPKTSERSRPRLRKMLSMDMSSSS
ADSGSLVSSEPTQCTMLYSRQGTTETIEEVEAEVEEEAVEEEE-------KE--------
-----EYGVGY-----G----VE--EDDDDELPQVSTDDGEVEAPPSYSKAVTCEHLSFG
-SQDGIGAKNQMVVSPDDSR-----TDKLGSSLLPPLTHELTASELLLNKMFHDDE--LE
ESERFYVGQPRFLLLFYAMYNTLVARSEMVCYFVIILNHMVSASMITLLLPILIFLWAML
SVPRPSRRFWMMAIVYTEVAIVVKYFFQFGFFPWNKNVEV--HKDKPYHPPNIIGVEKKE
GYVLYDLIQLLALFFHRS--ILKCHGLWDEDDVVDSGTDKEDSDAEL---SLGHSRRDSA
---DSLKSINLAASVES-----------------VHVTFPEPPTAVRRK--RSSCSSPVS
PGSSFSSNRSKR-----GST-STRNSSQKG--GSILGVK-----QRSRRELY-VKKLQE-
--------------H-LVQAKNFTIRKTLQIYVPIRQFFYNLIHPDYSAVTDVYVLMFLA
DTVDFVIIVFGFWAFGK-HSAAADITSSLSEDQVPGPFLVMVLIQFGTMVVDRALYLRKT
VLGKVIFQVILVFGIHFWMFFILPVVTERKFSQNLVAQLWYFVKCVYFGLSAYQIRCGYP
TRVLGNFLTKSYNYVNLFLFQGFR

PF12166 // ENSGT00390000013029_1_Domain_3 (2665, 3094)

LVPFLTELRAVMDWVWTDTTLSLSSWICVEDIYAHI
FILKCWRESEKRYPQPRGQKKKKVVKYGMGGMIIVLLICIVWFPLLFMSLIKSVAGVINQ
PLDVSVTITLGGYQVTGHTSQY----KT---APTSIYACA-----FVCIQGAMQFLENYE
REDITVAELEGNSNSLWTISPPSKQKMIQELKDPNSSFSVVFSWSIQRNMSLGAKAEIAT
DKLTFPLKNVTREQIAKMIAGNDTESSKMPVTIEKLYPYYVKAPSDSNSKPIKQLLS--E
KDFMNITI-------------ILSRDNMTKSNSEWWVLNLTGNRIYDREAQALELVVFND
KVSPPSLGFLAGYGIMGLYASVVLVIGKFVREFFSGISHSIMFEELPNVDRILKLCTDIF
LVRETGELELEEDLYAKLIFLYRSPETMIKWTREKTN

------------------------------------------------------------
------------------------------------------------------------
-------------SLKGADAGNGIRVFVPDVGMFIASLTIWLVCRNIVQKPVAEEAAQCN
PEFENEESAGGEKIDSEEALIYE-EDLDEGDGAEGDLEESAKLKLFRRLASVASKLKEFI
GNMITTAGKVVVTILLGS-SGMMLPSLTSSVYFFVFLGLCTWWSWCRTFDPLLFSCLCVL
LAIFTAGHLIGLYLYQFQFFQEAVPPNDYYA-RLFGIKSVIQTDCSSTWKIIANPDLSWY
HHANPIVLLVMYYTLATLI-RIWLQEPV--VQEERTKE------EDRALACSPAPI-TAE
RRRSLWYATHYPTDERKLLSMTQDDYKPSDGLLVTVNGNPVDYHTIHPSLPLENGPAKAD
LYSTPQYRWEPAAASPEKKEE-DDDEKEEFEEERSREEKRSVKVHAMVSVFQFIMKQSYI
CALIAMM-AWSITYHSWLTFVLLIWSCTLWMIRNRRKYAMISSPFMVVYGNLLLILQYIW
SFELP--EIKKVPGFLEKKEPGELAS---------KILFTITFWLLLRQHLTEQKALQEK
EALLSEVKIGSQEREEK-----DD-EQDLQVD---SEAQEKEEEEEPKEEQQE-------
-------------------RR-EEE--EEEEADEQDVMKVLGNLVVALFIKYWIYVCGGM
FFFVSFEGKIVMYKIIYMVLFLFCVALYQVHYEWWRRILKYFWMSVVIYTMLVLIFIYTY
QFENFPGLWQNMTGLKKEKLEDLGLKQFTVAELFTRIFIPTSFLLVCILHLHYFHDRFLE
LTDLKSIPSKEDSAIY-------------------------RLAHPEGSLPDLAMMKLTA
SLEVAEVKQLAGPGEEMPGGCPAKAKK--GEP--GRDSEDEDEDED----------EEEE
ETSDLRNKWHLVIDRLTVLLLRFLEGFHQLQTFLWWILELHIVKIVSSYIIWVSVKE--V
SLFNYVFLISWAFALPYARLRRLASSVCTVWTCVIIVCKMLYQLQTIKPENFSVNCSLPN
ENQTNIP-LHQLNKSLLYSAP-IDPTEWVGLRKSSPLLVYLRNNLLMLAILAFEVTVYRH
QEYYRGRNNLSTPVSKTIFHNITRLQLDDGLVNCAKYFINYFFYKFGLETCFLMSVNVIG
QRMDFYAMIHACWLIAVLYRRRRKAIAEIWPKYCCFLACIITFQYFICIGIPPAPCRDYP
WRFKGASFNDNIVKWLYFPDFIVRPNPVFLVYDFMLLLCASLQRQIFEDENKAAVRIVAG
DNVEICMNLDAASFSQHNPVPDFIHC-RSYLDMSKVVIFSYLFWFVLTIIFITGTTRISI
FCMGYLVACFYFLLFGGDLLLKPIKSILRYWDWLIAYNVFVITMKNILSIGACGYIEKLV
QNSCWLIQAFSLACTVKGYKM--------PDDDSSCKLPSGEAGIIWDSICFAFLLLQRR
VFMSYYFLHVVA--------DIKASQILASRGAELFQATIVKAVKARIEEEKKSMDQLKR
QMDRIKARQQKYKKGKERMLSLTQESGEGQDLQKVSEEDDE-READKQKTKGKKKQWWRP
WVDHASMVRSGDYYLFETDSEEEEEEELKKEDEEPPRRSAF-------------------
--------------QFVYQAWITDPKTALRQRRKEKKRSAREEQKRRRKESGEGP--VEW
EDREDEPVKKKSDGPDNIIKRIFNILKFTWVLFLATVDSFTTWLNSISREHLDISTVLRI
ERCMLTREIKKGN-VPTRESI-HMYYQNHI-MNLSRESGLDTIDEHAGTAAGAQTAHRMD
SLD---SHDSIS------------------------------------------------
--------SEPTQCTMLYSRQGTTETIEEVEAEQDEEAPE-G------------------
-------------------------AR-EAESPQDPTEDGDVEAPPSYSKAVSFERLSFD
-SRDDSAGQTHMEVSPDDS-----RSDRLEASILPPLTHELTASELLLNKMFHDDE--LE
ESEKFYVGQPRFLLLFYALYNTLVARSEMVCYFVIILNHMVSASMITLVLPILIFLWAML
SVPRPSRRFWMMAIVYTEVAIVVKYFFQFGFFPWNKNVEL--NKDKPYHPPNIIGVEKKD
AYVLYDLIQLLALFFHRS--ILKCHGLWDEDDIVDSGSDKVDSDDELSLG---HGRRASS
---DSLKSINLAASVE--------S---------VHVTFPEQP-AAVR-RKRSSSGSQTS
QGSSFSSNRSKR-----GS-TSTRNSSQKG--SSVVSVK-----QKSRRELY-MEKLQD-
--------------H-LIKAKAFTIKKTLQLYVPIRQFFYDLIHPDYSAVTDVYVLMFLA
DTVDFVIIVFGFWAFGK-HSAAADITSSLSEDQVPGPFLVMVLIQFGTMVVDRALYLRKT
VLGKVIFQVILVFGIHFWMFFILPGVTERKFSQNLVAQLWYFVKCVYFGLSAYQIRCGYP
TRVLGNFLTKSYNYVNLFLFQGF

PF12166 // ENSGT00390000013029_1_Domain_3 (2664, 3095)

RLVPFLTELRAVMDWVWTDTTLSLSSWICVEDIYAHI
FILKCWRESEKRYPQPRGQKKKKVVKYGMGGMIIVLLICIVWFPLLFMSLVKSVAGVINQ
PLDVSVTITLGGYQPIFTMSAQQSQLKVMDQPMFNKFIKA-----FSKDTGAMQFLENYE
KEDITVAELEGNSNSLWTISPPSKQKMIHELKDPNSSFSVVFSWSIQRNMSLGAKAEIAT
DKLSFPLKNATRENIAKMIAGGDTESSRTPVTIERIYPYYVKAPSDSNSKPIKQLLS--E
NNFMNITI-------------ILSRDNATNSNSEWWVLNLTGNRIYNQEAQALELVVFND
KVSPPSLGFLAGYGIMGLYASVVLVIGKFVREFFSGISHSIMFEELPNVDRILKLCTDIF
LVRETGELELEEDLYAKLIFLYRSPETMIKWTREKTN

------------------------------------------------------------
------------------------------------------------------------
-------------SLKGADAGNGIRVFVPDIGMFIASLTIWLICRNIVQKPVTEEAAQYN
PEFENEELTGGEKIDPEEALIYE-EDLNGGDGEEDELEESTKLKMFRRLASVASKLKEFI
GNMITTAGKVVVTILLGS-SGMMLPSLTSSVYFFVFLGLCTWWSWCRTFDPLLFSCLCVL
LAIFTAGHLIGLYLYQFQFFQEAVPPNDYYA-RLFGIKSVIQTDCSSTWKIIVNPELSWY
HHANPILLLVMYYTLATLI-RIWLQEPL--VQEEGVK------EEDRALACSPVQI-TAE
RRRSLWYAAHYPTDERKLLSMTQDDYKPSDGLLVTVNCTTVDYHTIHPGLPLENGPK-AD
RYSTPQYRWEPSEGSSEKKEE-EEYENEEYEEERSHEDKRSVKVHAMVSVFQFIMKQSYI
CALIAMM-AWSITYHSWLTFVLLIWSCTLWMIRNRRKYAMISSPFMVVYGNLLLILQYIW
SFELP--EIKKVPGFLEKKDPGELAS---------KILFTITFWLLLRQHLTEQKALQEK
EALLSEVKIGSQENEDK-----DDERQDSQV---EGEPKEK-------------------
-----EEEEEAKEEKQEKKKAEEE-DVEEDDDDDQDVMKVVGNLVVTMFIKYWIYVCGGM
FFFVSFEGKIVMYKIIYMVLFLFCVALYQVHYEWWRRILKYFWMSVVIYTMLVLIFIYTY
QFENFPGLWQNMTGLKKEKLEDLGLKQFTVAELFTRIFIPTSFLLVCILHLHYFHDRFLE
LTDLKSIPSKEDNTIYSHAKVNGRVYLIIN-----------RLAHPEGSLPDLTMMNLAA
SLEKQELRKVEEPQEEKLEGTYEREE--KAEPGKDSQGSEEEEE-EESEREESGEEEEEE
ETSDLRNKWHLVIDRLTVLFLKFLEYFHKLQVFMWWILELHIIKIVSSYIIWVSVKE--V
SLFNYVFLISWAFALPYAKLRRLASSVCTVWTCVIIVCKMLYQLQTIKPENFSVNCSLPN
ENQTNID-PEQLNSSLLYSAP-IDPTEWVGLRKSSPLLVYLRNNLLMLAILAFEVTIYRH
QEYYRGRNNLTAPVSRTIFHDITRLHLDDGLINCAKYFINYFFYKFGLETCFLMSVNVIG
QRMDFYAMIHACWLIAVLYRRRRKAIAEVWPKYCCFLACIITFQYFICIGIPPAPCRDYP
WRFKGASFNNNIIKWLYFPDFIVRPNPVFLVYDFMLLLCASLQRQIFEDENKAAVRIMAG
DNVEICMNLDAASFSQHNPVPDFIHC-RSYLDMSKVIIFSYLFWFVLTVIFITGTTRISI
FCMGYLVACFYFLLFGGDLLLKPIKSILRYWDWLIAYNVFVITMKNILSIGACGYIETLV
HNSCWLIQAFSLACTVKGYK--------MPDSNASCRLPSGEAGIIWDSICFAFLLLQRR
VFMSYYFLHVVA--------DIKASQILASRSDDHIQLTLRKKSKAIIVAHKQPFH-NSQ
RMDRIKARQQKYKKGKERMLSLTQESGECQDIQKLSEEDDE-READKQKAKGKKKQWWRP
WVDHASMVRSGDYYLFETDSEEEEEEELKKEEEEPPRRSAF-------------------
--------------QFVYQAWITDPKTALRQRRKEKKKSTREEQKRRRKGSGEGP--VEW
EEREDEPIKKKSDGPDNIIKRIFNILKFTWVLFLATVDSFTTWLNSISREHIDISTVLRI
ERCMLTREIKKGN-VPTRESI-HMYYQNHI-MKLSRESGLDTIDEHPKAISGSQTAYRMD
SLE---SHDSISSCYTEATMLFSRQSTLDDLDGPETVPKTSERARPRLRKMFSMDVSSSS
ADSGSLASSEPTQCTLLYSRQGTTETIEEVEAEQEEEAVGPGPAFEHAVDEEEAE-----
-------------CDMGAETISLTPE---NELPQYSTMEGDVEAPPSYSKAVSFERLSFG
SQDDGSTGKNHMVVSPDDSRTD-----KLESSILPPLTHELTASELLLNKMFHDDE--LE
ESEKFYVGQPRFLLLFYAMYNTLVARSEMVCYFVIILNHMVSASMITLVLPILIFLWAML
SVPRPSRRFWMMAIVYTEVAIVIKYFFQFGFFPWNKNLEF--YKDKPYHPPNIIGVEKKE
GYVLYDLIQLLALFFHRS--ILKCHGLWDEDDIVEHGTDKDDSDDEL---SLSHGRRDSS
---DSLKSINLAASVES-----------------VHVHFPEQQTAIRRKS--SSSNSQIS
HRSSFSSNRSRR-----GST-STRNSSQKG--SSVLSIK-----HKSKRELY-MEKLQEH
LIKAKAF----------------TIKKALQIYVPIRQFFYNLIHPDYSAVTDVYVLMFLA
DTVDFIIIVFGFWAFGK-HSAAADITSSLSEDQVPGPFLVMVLIQFGTMVVDRALYLRKT
VLGKVIFQVILVFGIHFWMFFILPGVTERKFSQNLVAQLWYFVKCVYFGLSAYQIRCGYP
TRVLGNFLTKSYNYVNLFLFQGF

PF12166 // ENSGT00390000013029_1_Domain_3 (2664, 3095)

RLVPFLTELRAVMDWVWTDTTLSLSSWICVEDIYAHI
FILKCWRESEKRYPQPRGQKKKKVVKYGMGGMIIVLLICIVWFPLLFMSLIKSVAGVINQ
PLDVSVTVTLGGYQPIFTMSAQQSQLKVMNQSKFQAFMNG-----FSKDTGAMQFLENYE
KEDITVAELEGNSNSLWTISPPSKQKMIHELTDPNSSFSVVFSWSIQRNMSLGAKAEIAT
DKLSFPLQNNTRESIAKMIAGNNTESSKTPVTIEKIYPYYVKAPSDSNSKPIKQLLS--E
NKFMNITI-------------ILSRDNTTQSNSEWWVLNLIGNRIYNQHAQALELVVFND
KVSPPSLGFLAGYGIMGLYASVVLVIGKFVREFFSGISHSIMFEELPNVDRILKLCTDIF
LVRETGELELEEDLYAKLIFLYRSPETMIKWTREKTN

------------------------------------------------------------
------------------------------------------------------------
--------------------------------MFIASLATWLVCRNIVQKPMSEDSAQYN
MQFENEEMAGGEKADSEEALIYE-EELDAGDAVEGELEESTKLKILRRFASLASRLKEFI
GNMIATAGKVVVTILLGS-TGMMLPSLTSSVYFFVFLGLCTWWSWCRTFDPLIFSCLCVL
MAIFSAGHLIGLYLYQFQFFQEAVPPGDYYA-RLFGITSVIQTNCSSTWKIIVHPRLSWY
HHANPILLLVTYYTLATLI-RLWLQEPIERVQEDETN------DEDKDLSCSPMQI-TAE
RRRSLWYATHYPTDEKKLLSMTQDDYKPSDVLLVTVNGAPVDYHTIHPSLPIENGPAKGD
MYSTPQYRWETSEETSEKKEE-EEDK-EDEDEEKSQEEKPNVKVHAMVSVFQFIMKQSYI
CALIAMM-AWSITYHSWLTFVLLIWSCTLWMIRNRRKYAMISSPFMVVYGNLLLTLQYIW
SFDLE--EIKEVPGFLEKKAPTELAS---------KILFTITFWLLLRQHLTEQKALQLK
EALLSEVKIGSQEDEEK----EDDELQDIQV---EGEAKEKEE-----------------
-----------DQGKIKKQESKKEE-EHEEEDDDQDIMKVMGNLVMAMFIKYWIYVCGGM
FFFVSFEGTIVMYKIIYMVLFLFCVALYQVHYEWWRKILKYFWMSVVIYTMLVLIFIYTY
QFENFPGLWENMTGLNQKKLEDLGLKKFTITELFTRIFIPTSFLLVCILHLHYFHDRFLE
LTDLKSIPSKEDNTIYSHAKVNGRVYLIINSIKKKLPIHQNELANPEGSLPDLAMMNLTA
SMEKEAMKKIEEDGQDKTEEYYEEEEKG--GDRKDIRKSHGAN------ITF-HSLRLNS
CFTDLRNKWHLVIDRLTVLFLKFLEYFHKLQVFMWWILELHIIKIVSSYIIWVTTIK-EV
SLFNYVFLISWAFALPYAQLRRLASSICTVWTCVIIVCKMLYQLSTIDPVKFSVNCTWVS
HLDGKSY-LYFWENSLWGKLGPIDPSEWVGLRKSSPLLVYLRNNLLMLAILAFEVTIYRH
QEYYRCRNNLTAPVSKTIFHDITRLHLDNGLINCAKYFINYFFYKFGLETCFLMSVNVIG
QRMDFYAMIHACWLIAVLYRRRRKAIAEIWPKYCCFLACIITFQYFVCIGIPPAPCRDYP
WRYYGASFNNNIIKWLYFPDFIVRPNPVFLVYDFMLLLCASLQRQTFEDENKAAVRIMAG
DNVEICMSLDAASFSQHNPVPDFIHC-RSYLDMYKVVIFSYLFWFVLTIIFITGTTRISI
FCMGYLVACFYFLLFGGDLLLKPIKSILRYWDWLIAYNVFVITMKNILSIGACGYIESLV
RNSCWLIQAFSLACTVKGYK--------MPLDHKDCKLPSGEAGIIWDSICFAFLLLQRR
VFMSYYFLHVVA--------DIKASQILASRGAELFQATIVKAVKARMEEEKKSMDQLKR
QMDRIKARQQKYKKGKERMLSLTQESGEGQSLQRVSEEDDE-READKQKAKGKKKQWWRP
WVDHASMVRSGDYYLFETDSEEEEEEEEK-KEEEPPRKSAFQRAIGKFASAILALPKSVI
KLPKTILQYLIRAAKFVYQAWITDPKTALRQRRKEKKRSAREEQKRRRKGSGEGP--VEW
EDREDEPIKKKSDGPDNIIKRIFNILKFTWVLFLASVDSFTTWLNSISREHIDISTVLRI
ERCMLTREIKKGN-VPTRESI-HMYYQNHI-MNLSRESGLDTIDGNPGAASGLKTARRMD
SLD---SHDSISSCYTEATMLFSRQSTLDDLDGPETVPKTSERARPRLRKMYSMDMSSSS
ADSGSLASSEPTQCTMLYSRQGTTETIEEVEAEHEEEVVGPLPELKDEEDDEY-------
-------DEDSVEVDLT-SDAELPQYSTMDTMDTMDTVDGDVEAPPSYSKAVSFEHLSFD
SHD-VSDDKNHMVVSPDDSRTD-----KSGSSIPLPLTHELTASELLLNKMFHDEE--LE
ESEKFYVDQPRFLLLFYALYNTLVARSEMVCYFVIILNHMISASMITLVLPILIFLWAML
SVPRPSRRFWMTAIVYTEVAIVIKYFFQFGFFPWNKNLDF--YKDKPYHPPNIIGVEKKE
GYVLYDLIQLLALFFHRS--ILKCHGLWDEDDTVDTGTNKDDSDDEL---SLNMGRRDSS
---DSMKSVNLAASVES-----------------VHVHFPEQQAAIRRKS--SSSNSHLS
HRSSFSSNRSKR-----GST-STRNSSQKG--SSVLSIK-----QKSKRELY-MEKFQEH
FIKAKAF----------------TIKKTLQIYVPIRQFFYNLIHPDYSAVTDVYVLMFLA
DTVDFIIIVFGFWAFGK-HSAAADITSSLSEDQVPEAFLVMVLIQFGTMVVDRALYLRKT
VLGKVIFQVILVFGIHFWMFFILPGVTERKFSQNLVAQLWYFVKCVYFGLSAYQIRCGYP
TRVLGNFLTKSYNYVNLFLFQGF

PF12166 // ENSGT00390000013029_1_Domain_3 (2664, 3095)

RLVPFLTELRAVMDWVWTDTTLSLSSWICVEDIYAHI
FILKCWRESEKRYPQPRGQKKKKVVKYGMGGMIIVLLICIVWFPLLFMSLIKSVAGVINQ
PLDVSVKITLGGYQPIFTMSAQQSQLKVMEPAMFKSFLKN-----HSTNTNAMQFLENYQ
REDITIVELEGNSNSLWTISPPSKLKMINELTDFKNSFSLVFSWSIQRNMSLGAKAEIAS
DKLSFTLENETRISIAQMMSDSKF--TAIPATIKGIYPYYLKAPSDANTKPIKQLLK--E
NNFKDITI-------------ILRRDNKSVIENEWWVLDLLGNKLLNQDQKGLELVVFND
KVSPPSLGFLAGYGIMGLYASVVLVIGKFVREFFSGISHSIMFEELPNVDRILKLCTDIF
LVRETGELELEEDLYAKLIFLYRSPETMIKWTREKDN

----------MASEVVCGLVFRLLLPVCLAVACAFRYNGLSFVYLIYLLLIPLFSEPTKA
T------MQGHTGRLLKSLCLLSLSFLLLHIVFHIT-----LASLEAQHRITPGYNCSTW
EKTFRQIGFE---SLEGADAGNGIRVFVPDIGMFIVSLTIWLVCRNMVQKPAVEETARDT
PEFENEELARGEKMDSKEALIED-EDLDGADMEDTEGEDSARLRLFRQLASLASRLKEFV
GNMITTAGKVVVTILLGS-SGMMLPSLTSAVYFFVFLGLCTWWSWCRTFDPLLFSCLCVL
LAIFTAGHLIGLYLYQFQFFQEAVPPNDYYA-RLFGIKSVIQTDCSSTWKIIVNPDLSWY
HHANPILLLVMYYTLATLI-RIWLQEPL--VPDEMAK------DEDCALGDSPSQH-SAE
RRRSLWYAAHYPTDERKLLSMTQDDYKPSDGLLVTVNGNPVDYHTIHPSLPLENGPAKAD
LYSTPHYRWEPLEGSAEKKED-EEYEKEESEGERSREDKRSVKVHAMVSVFQFIMKQSYI
CALIAMM-AWSITYHSWLTFVLLIWSCTLWMIRSRRKYAMVSSPFMVIYANLLLVLQYIW
SFELP--EIKKVPGFLEKKEPGELAS---------KILFTITFWLLLRQHLTEQKALREK
EALLSEVKIGSQENEEK-----DEDLEEVQV---EGEPKEKEE-----------------
-----EEG---EGPKEEKQETKEEEEEAEEDGDDQDIMKVLGNLVVAMFIKYWIYVCGGM
FFFVSFEGKIVMYKIIYMVLFLFCVALYQVHYEWWRKILKYFWMSVVIYTMLVLIFIYTY
QFENFPSLWQNMTGLKKEKLEDLGLKQFTVAELFTRIFIPTSFLLVCILHLHYFHDRFLE
LTDLKAIPSKEDSTIYSHAKVNGRVYLIRN-----------RLAHPEGSLPDLAMMHLTP
SLDKPEVHKQAEPGQQHPEGQEQTEEGRKGEPSKDGKDSEEDSE-EDSEE-------EEE
LEEEEELKWHLVIDRLTVLFLKFLEFFHKLQVFVWWMLELHITKIVSSYIIWVSVKE--V
SLFNYVFLISWAFALPYAKLRRLASSVCTVWTCVIIVCKMLYQLQTIKPSTFSVNCTLPN
ENQTNIP-LKELNKSLLYSAP-IDPTEWVGLRKSSPLLVYLRNNLLMLAILAFEVTIYRH
QEYYRGRNKLTAPVSKTIFHDVTRLHLDDGLLSCAKYFTNYFFYKFGLETCFLLSVNVIG
QRMDFYAMIHACWLIGVLYRRRRKAIAEVWPKYCCFLACILTLQYLVCIGVPPAPCRDYP
WRLKGADFNDNIIKWLYFPDFIVRPNPVFLVYDFMLLLCASLQRQIFEDENKAAVRIMAG
DNVEICMNLDAASFSQHNPVPDFIHC-RSYLDMSKVVIFSYLFWFVLTIIFITGTTRISI
FCMGYLVACFYFLLFGGDLLLKPIRSILRYWDWLIAYNVFVITMKNILSIG

PF15917 // ENSGT00390000013029_1_Domain_0 (1492, 1774)

ACGYIGTLV
KNSCWLIQAFSLACTVKGYT--------MPSDDASCKLPSGEAGIIWDSICFAFLLLQRR
VFMSYYFLHVVA--------DIKASQILASRGAELFQATIVKAVKARIEEEKKSMDQLKR
QMDRIKARQQKYKKGKERMLSLTQESGEGQDTQKLSEEDDE-READKQKAKGKTKQWWRP
WVDHASMVRSGDYYLFETDSEEEEEEELKKEDEELPRKSAF-------------------
--------------QFVYQAWITDPKTALRQRR

ENSGT00390000013029_1_Linker_0_3 (1774, 2665)

TEKKKSAREEQKCKRRGSGEGL--VDW
EDREEEPVKKKSDGPDNIIKRIFNIVKFTWVLFLATVDSFTTWLNSISREHIDISTVLRI
ERCMLTREIKKGN-VPTRESI-HMYYQNHI-MNLSQESGLDTIEDQPGARPGAPPAHRMD
SLD---SHDSISSCYTEATMLFSRQSTLDDLDGPDPVPKTSERSRPRLRKMLSMDMSSSS
ADSGSLASSEPTQCTMLYSRQGTTETIEEVEAEAEEETVGE-----EEEEEEEHG-----
-----------AECGAEAEEASLSPEDEEDEPPLLSTNDGDMEVPPSYSKAVSFEHLSFG
SQD-GAEAKNHMVVSPDDSRTD-----KLESSLLPPLTHELTASELLLNKMFHDDE--LE
ESERFYVGQPRFLLLFYAMYNTLVARSEMVCYFVIILNHMVSASMITLLLPILIFLWAML
SVPRPSRRFWMMAIVYTEVAIVVKYFFQFGFFPWNKNVEI--HKDKPYHPPNIIGVEKKE
GYVLYDLIQLLALFFHRS--ILKCHGLWDEEEAVDSGTDKADSDAEL---SLSRSRRDSA
---DSLKSIDLAASVES-----------------VQVTFPEPPRALRRKR--SSSSGRDS
PGSSFSSNRSKR-----GST-STRNSSQKG--SSILSVK-----QKSRRELY-VKKLQGH
LVRAKAF----------------TIRKTLQIYVPIRQFFYNLIHPDYSAVTDVYVLMFLA
DTVDFIIIVFGFWAFGK-HSAAADITSSLSEDQVPGPFLVMVLIQFGTMVVDRALYLRKT
VLGKVIFQVILVFGIHFWMFFILPGVTERKFSQNLVAQLWYFVKCVYFGLSAYQIRCGYP
TRVLGNFLTKSYNYVNLFLFQGFR

PF12166 // ENSGT00390000013029_1_Domain_3 (2665, 3094)

LVPFLTELRAVMDWVWTDTTLSLSSWICVEDIYAHI
FILKCWRESEKRYPQPRGQKKKKVVKYGMGGMIIVLLICIVWFPLLFMSLIKSVAGVINQ
PLDVSVTITLGGYQPIFTMSAQQSQLKVMDNQRF---------------GGAMQFLENYE
REDITVAELEGNSNSLWTISPPSKQKMIQELTDPNSSFSVVFSWSIQRNMSLGAKAEIAT
DKLTFPLKNVTRESIAKMIAGNDTESSKTPVTIEKIYPYYVKAPSDSNSKPIKQLLS--E
KDFMNITI-------------ILSRDNTIKSSSEWWVLNLTGDRVYDQESQALELMVFND
KVSPPSLGFLAGYGIMGLYASVVLVIGKFVREFFSGISHSIMFEELPNVDRILKLCTDIF
LVRETGELELEEDLYAKLIFLYRSPETMIKWTREKTN

MRDPSAVSEDEQQDHQCE-------NYTGLSACAFRYNGLSFVYLIYLLLIPLFSEPTKA
T------MQGHTGRLLKSLCFTSLSFLLLHIIFHIT-----LASLKAQHRIAPGYNCSTW
EKTFRQIGFE---SLKGADAGNGIRVFVPDIGMFIASLTIWLVCRNMVQKPALEEAAQDT
PEFENEELARGEKMDSKEALIED-EDLDGAGVEDTEGENSTRLRLFRQLASLASRLKEFV
GNMITTAGKVVVTILLGS-SGMMLPSLTSAVYFFVFLGLCTWWSWCRTFDPLLFSCLCVL
LAIFTAGHLIGLYLYQFQFFQEAVPPNDYYA-RLFGIKSVIQTDCSSTWKIIVNPDLSWY
HHASPILLLVMYYTLATLI-RIWLQEPL--VPDEMAKD------EDRALGDSPNQP-SAE
RRRSLWYTAHYPVDERKLLSMTQDDYKPSDGLLVTVNGNPVDYHTIHPSLPLENGPAKAD
LYSTPRYRWEPSEGSTEKKED-EEYGKEEFEEEGSQEDKRSIKVHAMVSVFQFIMKQSYI
CALISMM-AWSITYHSWLTFVLLIWSCTLWMIRSRRKYAMISSPFMVVYADLLLVLQYIW
SFELP--EIKKVPGFLEKKMPGELAS---------KILFTITFWLLLRQHLTEQKAIREK
EALLSEIKIGSQEGEEK-----DEELGEVQVE---GEPKEKEEEEEPKEEKQE-------
-------------------RKKEE---EEEDEDDQDIMKVLGNLVVAMFIKYWIYVCGGM
FFFVSFEGKIVMYKIIYMVLFLFCVALYQVHYEWWRKVLKYFWMSVVIYTMLVLIFIYTY
QFENFPSLWENLTGLRKEKLEDLGLKQFTVAELFTRIFIPTSFLLVCILHLHYFHDRFLE
LTDLKAIPSKEDSTIYR-------------------------LAHPEGSLPDLAMMHLTP
SLDKPEAKKQAEPGQEQPEGQEQTE-Q--GRK--GELAQDCGED--------SEEEEVEE
EVSDLRNKWHLVIDRLTVLFLKFLEYFHKLQVFMWWMLELHITKIVSSYIIWVSVKE--V
SLFNYVFLISWAFALPYSKLRRLASSVCTVWTCVIIVCKMLYQLQTIKPSSFSINCTLPD
ENQTNIP-LKELNKSLLYSAP-IDPTEWVGLRKSSPLLVYLRNNLLMLAILAFEVTIYRH
QEYYRGRNNLTAPVSKTIFHDITRLHLDDGLVNCAKYFINYFFYKFGLETCFLLSVNVIG
QRMDFYAMIHACWLIGVLYRRRRKAIAEVWPKYCCFLACILTLQYLVCIGVPPAPCRDYP
WRLKGADFNDNIIKWLYFPDFIVRPNPVFLVYDFMLLLCASLQRQIFEDENKAAVRIMAG
DNVEICMNLDAASFSQHNPVPDFIHC-RSYLDMSKVIIFSYLFWFVLTIIFITGTTRISI
FCMGYLVACFYFLLFGGDLLLKPIRSILRYWDWLIAYNVFVITMKNILSIG

PF15917 // ENSGT00390000013029_1_Domain_0 (1492, 1775)

ACGYIGTLV
KNSCWLIQAFSLACTVKGYTM--------PSDDVSCKLPSGEAGIIWDSICFAFLLLQRR
VFMSYYFLHVVA--------DIKASQILASRGAELFQATIVKAVKARIEEEKKSMDQLKR
QMDRIKARQQKYKKGKERMLSLTQESGEGQDARKLSEADDE-READKQKAKGKKKQWWRP
WVDHASMVRSGDYYLFETDSEEEEEEEPKKEDEEPPRKSAF-------------------
--------------QFVYQAWITDPKTALRQRHK

ENSGT00390000013029_1_Linker_0_3 (1775, 2665)

EKKRSAREEQKCRRRGSREGP--VDW
EDREEEPVKKKSDGPDNIIKRIFNIVKFTWVLFLATVDSFTTWLNSISREHIDISTVLRI
ERCMLTREIKKGN-VPTRESI-HMYYQNHI-MNLSRESGLDTIEERPGAGPGTPPAHRMD
SLD---SHDSISSCYTEATTLFSRQSTLDDLDGPDPVPKTSERSRPRLRKMLSMDMSSSS
ADSGSLASSEPTQCTMLYSRQGTTETIEEVEAEAEEEAVGAQMEEEEEE-----------
---------------------------EDDVLPQLSTDDGDMEVPPSYSKAVSFEHLSFG
-SQDGAEAKNHMVVSPDDS-----RTEKLESSLLPPLTHELTASELLLNKMFQDDE--LE
ESERFYVAQPRFLLLFYAMYNTLVARSEMVCYFVIILNHMVSASMITLLLPILIFLWAML
SVPRPSRRFWMMAIVYTEVAIVVKYFFQFGFFPWNRNVEI--YKDKPYHPPNIIGVEKKE
GYVLYDLIQLLALFFHRS--ILKCHGLWDEDEAVDSGTDKDDSDTEL---SPGRGRRGSA
---DSLKSISLAASVES-----------------VHVAFPEPPMALCRK--RSSSSCPDS
PGSSFSSNRSER-----GST-STQNSSQKG--SGVLGVK-----QKGRRELY-VKKLQE-
--------------H-LVRAKAFTIRKTLQIYVPIRQFFYDLIHPDYSAVTDVYVLMFLA
DTVDFVIIVFGFWAFGK-HSAAADITSSLSEDQVPGPFLVMVLIQFGTMVVDRALYLRKT
VLGKVIFQVILVFGIHFWMFFILPGVTERKFSQNLVAQLWYFVKCVYFGLSAYQIRCGYP
TRVLGNFLTKSYNYVNLFLFQGFR

PF12166 // ENSGT00390000013029_1_Domain_3 (2665, 3094)

LVPFLTELRAVMDWVWTDTTLSLSSWICVEDIYAHI
FILKCWRESEKRYPQPRGQKKKKVVKYGMGGMIIVLLICIVWFPLLFMSLIKSVAGVINQ
PLDVSVTITLGGYQPIFTMSAQQSQLKVMDSQRFAAFIKK-----FSRDTGAMQFLENYE
REDITVAELEGNSNSLWTISPPSKQKMIQELTDPNSSFSVVFSWSIQRNMTLGAKAEIAT
DKLTFPLKNVTRESIAKMIAGNDTESSKTPVTIEKIYPYYVKAPSDSNSKPIKQLLS--E
KDFMNITI-------------ILSRDNTTKSNSEWWVLNLTGNRIYDQESQALELMVFND
KVSPPSLGFLAGYGIMGLYASVVLVIGKFVREFFSGISHSIMFEELPNVDRILKLCTDIF
LVRETGELELEEDLYAKLIFLYRSPETMIKWTREKTN

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SQE-D---------------------------VADAQKRRRTASELLRSRRLYVSE--LE
ESEQFYQSHNRFLKLLLAGYRCVTGHSDLLCYFTIILNNMVTGSVISLFLPILIFLWAML
SIPRPTKRFWMTAILFTEMTVVVKYLFQFGFFPWNGYITLLRYEGKPFFPPRILGLEKSI
HYIKYDLLQLLALFFHRS--LLLSYGLWDQDKTTDEKQESKEGEEKPEEA--VSSHQHHG
AGAGAIGRVRGARKGDRSHAAPLHEEAWEEDAGGGSTPVPTPHALLRIKA--GTPGMWPC
WTLA---------------------VTHAV--PHFMGVRKRMRRRCQKKSHA-QRKLKAF
GLRVKGF----------------ILTKAQYMYQPVCKFFRDILDTQSRAATDVYAYMFLA
DVVDFIIIVFGFWAFGK-HTAAADITSSLSENQVPEAFLFMMLFQFSTMVIDRALYLRKT
VLGKLIFQVTLVFGIHVWMFFILPYVTERLFRQNMVAQLWYFVKCIYFGLSAYQIRCGYP
TRILGNFLTKKYNHLNLFLFQGFRLVPFLVELRAVMDWVWTDTTLSLSNWMCVEDIYANI
FIIKCSRETEKKYPQPKGQKKKKVVKYGMGGLIILFLVGIIWFPLLFMSLVRSVVGIINH
PIDVTVNLKLGGYEPLFSTSSQQQYIQPFTSEEYDELTKE-----FESEPVAMQFISLFG
MEDIVTARVEGSSGSLCPAADAQDKHDTD--LAPGAPQRLELAQLLD---GTGISPCECP
EGVAGP--------LCSVGWCNPPLSLLPCRV

PF12166 // ENSGT00390000013029_1_Domain_3 (2913, 3095)

LPNLFPKYIRAPTGSEAEPIKQLLPDDL
DSYLDVEVQLKRE---------RRGSGRGEHFVEWWVLRQKDA--PPQEGNILPMIIFND
KVSPPSLGFLAGYGIMGLYVSIVLVIGKFVRGFFSEISHSIMFEELPYVDRILKLCHDIF
LVRETGELELEEELYAKLIFLYRSPETMIKWTREKN-

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PF12166 // ENSGT00390000013029_1_Domain_3 (2729, 2798)

MGGMIIVLLICIVWFPLLFMSLIKSVAGVTNK
PLDVSITITLGGYQPIFTMSAQQSQLKDMNRTDFRRFMRG-----FSGKAVSGCL-----
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-------------------------------------

----------MASEVVCGLVFRLLLPICLAVACAFRYNGLSFVYLIYLLLIPLFSEPTKA
T------MQGHTGRLLKSLCFTSLSFLLLHIIFHIT-----LASLEAQHRLAPAYNCSTW
EKTFRQIGFE---SLKGADAGNGIRVFVPDIGMFIASLTIWLVCRNIVQKPETEEAAQYN
SESENEELAEGEKMDSEEALIYE-EDLDEGEGVEGEMEESAKLKMFRRLASVASKLKEFI
GNMITTAGKVVVTILLGS-SGMMLPSLTSAVYFFVFLGLCTWWSWCRTFDPLLFSCLCVL
LAIFTAGHLIGLYLYQFQFFQEAVPPNDYYA-RLFGIKSVIQTDCSSTWKIIVNPDLSWY
HHANPILLLVMYYTLATLI-RIWLQEPL--VEDDKTK------EEDQALACSSNQN-TAE
RRRSLWYAAHYPTDERKLLSMTQDDYKPSDGLLVTVNGNPVDYHTIHPSLPIENGPAKTE
LYSTPQYRWETSESSEKKE---EEEDKEEFEEERSQEEKRSVKVHAMVSVFQFIMKQSYI
CALIAMM-AWSITYHSWLTFVLLIWSCTLWMIRNRRKYAMISSPFMVVYANLLLVLQYIW
SFELP--EIKKVPGFLEKKEPGELAS---------KILFTITFWLLLRQHLTEQKALQEK
EALLSEVKIGSEELEEK----EDEELQDIQVE---GEPREKEEDEEIK------------
----------------EEKQEKKREEEEEEEEDDQDIMKVLGNLVIAMFIKYWIYVCGGM
FFFVSFEGKIVMYKIIYMVLFLFCVALYQVHYEWWRKILKYFWMSVVIYTMLVLIFIYTY
QFENFPGLWQNMTGLKKEKLEDLGLKQFTVAELFTRIFIPTSFLLVCILHLHYFHDRFLE
LTDLKAIPSKEDNTIYR-------------------------LAHPEGSLPDLAMLNLTS
SLEK----KLVEPGEEKLEGYTEKAEKGELEK--DSN-----VS-EEDEDE-EEESEEEE
ETSDLRNKWHLVIDRLTVLFLKFLEYFHKLQVFMWWILELHIIKIVSSYIIWVT-V-KEV
SLFNYVFLISWAFALPYAKLRRVASSVCTVWTCVIIICKMLYQLQTIKPENFSVNCSLPN
ENQTNIPL-HELNKSLLYSAP-VDPTEWVGLRKSSPLLVYLRNNLLMLAILAFEVTIYRH
QEYYRGHNNLTAPVSKTIFHDITRLHLDDGLINCAKYFINYFFYKFGLETCFLMSVNVIG
QRMDFYAMIHACWLIAVLYRRRRKAIAEVWPKYCCFLACIITFQYFICIGIPPAPCRDYP
WRFKGANFNDNIIKWLYFPDFIVRPNPVFLVYDFMLLLCASLQRQIFEDENKAAVRIMAG
DNVEICMNLDAASFSQHNPVPDFIHC-RSYLDMSKVIIFSYLFWFVLTIIFITGTTRISI
FCMGYLVACFYFLLFGGDLLLKPIKSILRYWDWLIAYNVFVITMKNILSIG

PF15917 // ENSGT00390000013029_1_Domain_0 (1492, 1771)

ACGYIGALV
QNCCWLIQAFSLACTVKGYKMPN--------EDSSCKLPSGEAGIIWDSICFAFLLLQRR
VFMSYYFLHVVA--------DIKASQILASRGAELFQATIVKAVKARIEEEKKSMDQLKR
QMDRIKARQQKYKKGKERMLSLTQESGEGQDLQKLSEEDDE-READKQKAKGKKKQWWRP
WVDHASMVRSGDYYLFETDSEEEEEEELKKEDEEPPRKSAF-------------------
--------------QFVYQAWITDPKTALRQ-----------------------------
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----------MASEVVCGLIFRLLLPICLAVACAFRYNGLSFVYLIYLLLIPLFSEPTKT
T------MQGHTGRLLKSLCFISLSFLLLHIIFHIT-----LVSLEAQHRIAPGYNCSTW
EK---TFRQIGFESLKGADAGNGIRVFVPDIGMFIASLTIWLLCRNIVQKPVTDEAAQSN
PEFENEELAEGEKIDSEEALIYE-EDFNGGDGVEGELEESTKLKMFRRLASVASKLKEFI
GNMITTAGKVVVTILLGS-SGMMLPSLTSSVYFFVFLGLCTWWSWCRTFDPLLFSCLCVL
LAIFTAGHLIGLYLYQFQFFQEAVPPNDYYA-RLFGIKSVIQTDCSSTWKIIVNPDLSWY
HHANPILLLVMYYTLATLI-RIWLQEPL--VQDEGTK------EEDKALACSPIQI-TAG
RRRSLWYATHYPTDERKLLSMTQDDYKPSDGLLVTVNGNPVDYHTIHPSLPMENGPGKAD
LYSTPQYRWEPSDESSEKREE-EEEEKEEFEEERSREEKRSIKVHAMVSVFQFIMKQSYI
CALIAMM-AWSITYHSWLTFVLLIWSCTLWMIRNRRKYAMISSPFMVVYGNLLLILQYIW
SFELP--EIKKVPGFLEKKEPGELAS---------KILFTITFWLLLRQHLTEQKALQEK
EALLSEVKIGSQENEEK-----DEELQDIQV---EGEPKEE-------------------
-----EE-EEAKEEKQERKKVEQEE---AEEEDEQDIMKVLGNLVVAMFIKYWIYVCGGM
FFFVSFEGKIVMYKIIYMVLFLFCVALYQVHYEWWRKILKYFWMSVVIYTMLVLIFIYTY
QFENFPGLWQNMTGLKKEKLEDLGLKQFTVAELFTRIFIPTSFLLVCILHLHYFHDRFLE
LTDLKSIPSKEDNTIYR-------------------------LAHPEGSLPDLTMMHLTA
SLEKPEVRKLAEPGEEKLEGYSEKAQ--KGDLGKDSEESEEDGE-EE-----EESEE-EE
ETSDLRNKWHLVIDRLTVLFLKFLEYFHKLQVFMWWILELHIIKIVSSYIIWVSVKE--V
SLFNYVFLISWAFALPYAKLRRLASSVCTVWTCVIIVCKMLYQLQTIKPENFSVNCSLPN
ENQTNIP-FNELNKSLLYSAP-IDPTEWVGLRKSSPLLVYLRNNLLMLAILAFEVTIYRH
QEYYRGRNNLTAPVSRTIFHDITRLHLDDGLINCAKYFINYFFYKFGLETCFLMSVNVIG
QRMDFYAMIHACWLIAVLYRRRRKAIAEIWPKYCCFLACIITFQYFICIGIPPAPCRDYP
WRFKGASFNDNIIKWLYFPDFIVRPNPVFLVYDFMLLLCASLQRQIFEDENKAAVRIMAG
DNVEICMNLDAASFSQHNPVPDFIHC-RSYLDMSKVIIFSYLFWFVLTIIFITGTTRISI
FCMGYLVACFYFLLFGGDLLLKPIKSILRYWDWLIAYNVFVITMKNILSIG

PF15917 // ENSGT00390000013029_1_Domain_0 (1492, 1775)

ACGYIGTLV
HNSCWLIQAFSLACTVKGYQ--------MPAANSPCTLPSGEAGIIWDSICFAFLLLQRR
VFMSYYFLHVVA--------DIKASQILASRGAELFQATIVKAVKARIEEEKKSMDQLKR
QMDRIKARQQKYKKGKERMLSLTQEPGEGQDMQKLSEEDDE-READKQKAKGKKKQWWRP
WVDHASMVRSGDYYLFETDSEEEEEEELKKEDEEPPRRSAF-------------------
--------------QFVYQAWITDPKTALRQRHK

ENSGT00390000013029_1_Linker_0_3 (1775, 2665)

EKKRSAREERKRRRKGSKEGP--VEW
EDREDEPIKKKSDGPDNIIKRIFNILKFTWVLFLATVDSFTTWLNSISREHIDISTVLRI
ERCMLTREIKKGN-VPTRESI-HMYYQNHI-MNLSRESGLDTIDEHPGAASGAQTAHRMD
SLD---SHDSIS------------------------------------------------
--------SEPTQCTMLYSRQGTTETIEEVEAEQEEEAGSTAPEPREAKEYE--------
-------ATGYDVGAMGAEEASLTPE---EELTQFSTLDGDVEAPPSYSKAVSFEHLSFG
SQDD-SAGKNRMAVSPDDSRTD-----KLGSSILPPLTHELTASELLLKKMFHDDE--LE
ESEKFYVGQPRFLLLFYAMYNTLVARSEMVCYFVIILNHMVSASMITLLLPILIFLWAML
SVPRPSRRFWMMAIVYTEVAIVVKYFFQFGFFPWNKNVEV--NKDKPYHPPNIIGVEKKE
GYVLYDLIQLLALFFHRS--ILKCHGLWDEDDMTESGMAREESDDEL---SLGHGRRDSS
---DSLKSINLAASVES-----------------VHVTFPEQQTAVRRKR--SGSSSEPS
QRSSFSSNRSQR-----GST-STRNSSQKG--SSVLSIK-----QKGKRELY-MEKLQEH
LIKAKAF----------------TIKKTLEIYVPIKQFFYNLIHPEYSAVTDVYVLMFLA
DTVDFIIIVFGFWAFGK-HSAAADITSSLSEDQVPGPFLVMVLIQFGTMVVDRALYLRKT
VLGKVIFQVILVFGIHFWMFFILPGVTERKFSQNLVAQLWYFVKCVYFGLSAYQIRCGYP
TRVLGNFLTKSYNYVNLFLFQGFR

PF12166 // ENSGT00390000013029_1_Domain_3 (2665, 3094)

LVPFLTELRAVMDWVWTDTTLSLSSWICVEDIYAHI
FILKCWRESEKRYPQPRGQKKKKVVKYGMGGMIIVLLICIVWFPLLFMSLIKSVAGVINQ
PLDVSVTITLGGYQPIFTMSAQQSQLKVMDQQSFNKFIQA-----FSRDTGAMQFLENYE
KEDITVAELEGNSNSLWTISPPSKQKMIHELLDPNSSFSVVFSWSIQRNLSLGAKSEIAT
DKLSFPLKNITRKNIAKMIAGNSTESSKTPVTIEKIYPYYVKAPSDSNSKPIKQLLS--E
NNFMDITI-------------ILSRDNTTKYNSEWWVLNLTGNRIYNPNSQALELVVFND
KVSPPSLGFLAGYGIMGLYASVVLVIGKFVREFFSGISHSIMFEELPNVDRILKLCTDIF
LVRETGELELEEDLYAKLIFLYRSPETMIKWTREKTN

----------MASEVVCGLVFRLLLPICLAVACAFRYNGLSFVYLIYLLLIPLFSEPTKA
T------MQGHTGRLLQSLCITCLSFLLLHIIFHIT-----LASLEAQHRIAPAYNCSTW
EKTFRQIGFE---SLKGADAGNGIRVFVPDVGMFIASLTIWLVCRNIVKKPDTEEVAQFN
PDCENEELAGGEKMDSEEALIYE-EDLDGEEGMEGELEESTKLKMFRRLASVASKLKEFI
GNMITTAGKVVVTILLGS-SGMMLPSLTSAVYFFVFLGLCTWWSWCRTFDPLLFGCLCVL
LAIFTAGHLIGLYLYQFQFFQEAVPPNDYYA-RLFGIKSIIQTDCSSTWKIIVNPQLSWY
HHANPILLLVMYYTLATL-NRIWLQEPL--VQDEMAKE------DEGTLDCSSNQN-TAE
RRRSLWYATQYPTDERKLLSMTQDDYKPSDGLLVTVNGNPVDYHTIHPIFVY--------
---------------LEKKEE-DEDKKEGSEGEGSQEEKRSVRIHAMVTVFQFIMKQSYI
CALIAMM-AWSITYHSWLTFVLLIWSCTLWMIRNRRKYAMISSPFMVVYANLLLVLQYIW
SFELT--EIKKVPGFLEKKNPGELAS---------KILFTITFWLLLRQHLTEQKALREK
EALLSEVKIGSQELEER----EDEELQDIQVE---GEPPEKAEEEEIKEERHE-------
-------------------LKKE-EEEEVEEDDDQDIMKVLGNLVVALFIKYWIYVCGGM
FFFVSFEGKIVMYKIIYMVLFLFCVALYQVHYEWWRKILKYFWMSVVIYTMLVLIFIYTY
QFENFPGLWQNMTGLKKEKLEDLGLKQFTVAELFTRIFIPTSFLLVCILHLHYFHDRFLE
LTDLKSIPSKEDNTIYSHAKVNGRVYLIIN-----------RLAHPEGSLPDLAVMNMTT
SLDKPEVQKLVEAGEERPEECAKKAEK--GQP--GKDSDESEEEEDEE------EESEEE
ETSDLRNKWLLVIDRLTVLFLKFLEYFHKLQVFMWWILELHIIKIVSSYIIWVTVKE--V
SLFNYVFLISWAFALPYAKLRRVASSVCTVWTCVIIVCKMLYQLQTIKPENFSVNCSLPN
ENQTNIP-LNELNKSLLYSAP-VDPTEWVGLRKSSPLLVYLRNNLLMLAILAFEVTIYRH
QEYYRGRNNLTAPVSKTIFHDITRLHLDDGLVNCAKYFINYFFYKFGLETCFLMSVNVIG
QRMDFYAMIHACWLIGVLYRRRRKAIAEVWPKYCCFLACIITFQYFVCIGIPPAPCRDYP
WRFKGANFNDNIIKWLYFPDFIVRPNPVFLVYDFMLLLCASLQRQIFEDENKAAVRIMAG
DNVEICMNLDAASFSQHNPVPDFIHC-RSYLDMSKVIIFSYLFWFVLTIIFITGTTRISI
FCMGYLKACFYFLLFGGDLLLKPIKSILRYWDWLIAYNVFVITMKNILSIG

PF15917 // ENSGT00390000013029_1_Domain_0 (1492, 1775)

ACGYISALV
RNSCWLIQAFSLACTVKGYKM--------PEDDSKCKLPSGEAGIIWDSICFAFLLLQRR
VFMSYYFLHVVA--------DIKASQILASRGAELFQATIVKAVKARIEEEKKSMDQLKR
QMDRIKARQQKYKKGKERMLSLTQESGEGQDIQKLSEEDDE-READKQKAKGKKKQWWRP
WVDHASMVRSGDYYLFETDSEEEEEEELKKEDEEPPRKSAF-------------------
--------------QFVYQAWITDPKTALRQRRK

ENSGT00390000013029_1_Linker_0_3 (1775, 2665)

EKKKLAREEEKGRRKGSGEGP--VEW
DDREDGPVKKKSDGPDNIIKRIFNILKFTWVLFLATVDSFTTWLNSISREHIDISTVLRI
ERCMLTREIKKGN-VPTRESI-HVYYQNHI-MNLSRESGLDTIDEHPGAGSRAQAAHRMD
SLD---SHDSISSCYTEATLLISRQSTLDDLDGQDPVPKTT-------------------
-DSGSVASSEPTQCTMLYSRQGTTETIEEVEAEAEEEVVEGLESELHDEEDK--------
-----EYAAEYEAG---VEEVSL--TP-DEELPQFSTDDGDVEAPPSYSKAVSFEHLSFN
----------HMVVSRDDSSTDKL-----ESSILPPLTHELTASELLMNKMFHDDEYELE
ESEKFYVDQPRFLLLFYAMYNTLVARSEMVCYFVIILNHMISASIITLLLPILIFLWAML
SVPRPSRRFWMMAIVYTEVAKWQ--------------------NTRPYYIQTINGQSVGP
-------PEMLASAVTFS--ASQCHGLWDEDDIVDSGTDKEESDDEL---SLDHDRRGSS
---DSLKSINLAASVES-----------------VHVTFPEQPGPIRR--KRSCSSSQIS
PRSSFSSNRSKR-----GST-STRNSSQRG--SSVLSIK-----QKSKRELY-MEKLQ--
-------------EH-LIKAKAFTIKKTLQIYIPIRQFFYDLIHPDYSAVTDVYVLMFLA
DTVDFIIIVFGFWAFGK-HSAAADITSSLSEDQVPGPFLVMVLIQFGTMVVDRALYLRKT
VLGKVIFQVILVFGIHFWMFFILPSVTERKFSQNLVAQLWYFVKCVYFGLSAYQIRCGYP
TRVLGNFLTKSYNYVNLFLFQGFR

PF12166 // ENSGT00390000013029_1_Domain_3 (2665, 3094)

LVPFLTELRAVMDWVWTDTTLSLSSWICVEDIYAHI
FILKCWRESEKRYPQPRGQKKKKAVKYGMGGMIIVLLICIVWFPLLFMSLIKSVAGVINQ
PLDVSVTITLGGYQPIFTMSAQQSQLKVMDNTKYKAFLKS-----FTTNSGAMQFLENYE
KEDITVAELEGNSNSLWTISPPSKQKMIQELTDPNSCFSVVFSWSIQRNMTLGAKAEIAT
DKLSFPLANETRNNIAKMIAGNDTESSNTPVTIEKIYPYYVKAPSDSNSKPIKQLLS--E
SNFMNITI-------------ILFRDNVTKSNSEWWVLNLTGNRIYNQGSQALELVVFND
KVSPPSLGFLAGYGIMGLYASVVLVIGKFVREFFSGISHSIMFEELPNVDRILKLCTDIF
LVRETGELELEEDLYAKLIFLYRSPETMIKWTREKTN

----------MASEVVCGLIFRLLLPICLAVACAFRYNGLSFVYLIYLLLIPLFSEPTKT
T------MQGHTGRLLKSLCFISLSFLLLHIIFHIT-----LASLEAQHRIAPGYNCSTW
EK---TFRQIGFESLKGADAGNGIRVFVPDIGMFIASLTIWLLCRNIVQKPVTDEAAQSN
LEFENEELAGGEKIDSEEALIYE-EDLDGGDGVEGELEESTRLKMFRRLACVASKLKEFI
GNMITTAGKVVVTILLGS-SGMMLPSLTSSVYFFVFLGLCTWWSWCRTFDPLLFSCLCVL
LAIFTAGHLIGLYLYQFQFFQEAVPPSDYYA-RLFGIKSVIQTDCSSTWKIIVNPDLSWY
HHANPILLLVMYYTLATLI-RIWLQEPL--VQEERTK------EEDKALACSPIQI-TAE
RRRSLWYATHYPTDERKLLSMTQDDYKPSDGLLVTVNGNPVDYHTIHPSLPMENGPGKAD
LYSTPQYRWEPSDESSEKREE-EEEEKEEFEEERSREEKRSIKVHAMVSVFQFIMKQSYI
CALIAMM-AWSITYHSWLTFVLLIWSCTLWMIRNRRKYAMISSPFMVVYGNLLLILQYIW
SFELP--EIKKVPGFLEKKEPGELAS---------KILFTITFWLLLRQHLTEQKALREK
EALLSEVKIGSQENEEK-----DEELQDIQV---EGEPKEK-------------------
-----EEEEEAKEEKQERKKVEEEE---VEEEDEQDIMKVLGNLVVAMFIKYWIYVCGGM
FFFVSFEGKIVMYKIIYMVLFLFCVALYQVHYEWWRKILKYFWMSVVIYTMLVLIFIYTY
QFENFPGLWQNMTGLKKEKLEDLGLKQFTVAELFTRIFIPTSFLLVCILHLHYFHDRFLE
LTDLKSIPSKEDNTIYSHAKVNGRVYLIINSIKKKLPIHQNELAHPEGSLPDLTMMQLTA
KLEKPEVRKLAEPGEEKPEGYSEKAQ--KGDLGKDSEESEEDGE-EE-----EESEE-EE
ETSDLRNKWHLVIDRLTVLFLKFLEYFHKLQVFMWWILELHIIKIVSSYIIWVSVKE--V
SLFNYVFLISWAFALPYAKLRRLASSVCTVWTCVIIVCKMLYQLQTIKPENFSVNCSLPN
ENQTNIP-LNELNKSLLYSAP-VDPTEWVGLRKSSPLLVYLRNNLLMLAILAFEVTIYRH
QEYYRGRNNLTAPVSKTIFHDITRLHLDDGLINCAKYFINYFFYKFGLETCFLMSVNVIG
QRMDFYAMIHACWLIAVLYRRRRKAIAEIWPKYCCFLACIITFQYFICIGIPPAPCRDYP
WRFKGASFNDNIIKWLYFPDFIVRPNPVFLVYDFMLLLCASLQRQIFEDENKAAVRIMAG
DNVEICMNLDAASFSQHNPVPDFIHC-RSYLDMSKVIVFSYLFWFVLTIIFITGTTRISI
FCMGYLVACFYFLLFGGDLLLKPIKSILRYWDWLIAYNVFVITMKNILSIG

PF15917 // ENSGT00390000013029_1_Domain_0 (1492, 1775)

ACGYIGTLV
HNSCWLIQAFSLACTVKGYQ--------MPAANSPCTLPSGEAGIIWDSICFAFLLLQRR
VFMSYYFLHVVA--------DIKASQILASRGAELFQATIVKAVKARIEEEKKSMDQLKR
QMDRIKARQQKYKKGKERMLSLTQEPGEGQDMQKLSEEDDE-READKQKAKGKKKQWWRP
WVDHASMVRSGDYYLFETDSEEEEEEELKKEDEEPPRRSAF-------------------
--------------QFVYQAWITDPKTALRQRHK

ENSGT00390000013029_1_Linker_0_3 (1775, 2665)

EKKRSAREERKRRRKGSKEGP--VEW
EDREDEPIKKKSDGPDNIIKRIFNILKFTWVLFLATVDSFTTWLNSISREHIDISTVLRI
ERCMLTREIKKGN-VPTRESI-HMYYQNHI-MNLSRESGLDTIDERPGAASGAQTAHRMD
SLD---SHDSIS------------------------------------------------
--------SEPTQCTMLYSRQGTTETIEEVEAEQEEEAGSTVPEPREAKEYE--------
-------AAGYDVGAVGAEEASLTPE---EELTQFSTLDGDVEAPPSYSKAVSFEHLSFG
SQDD-SAGKNHMAVSPDDSRTD-----KLGSSILPPLTHELTASELLLNKMFHDDE--LE
ESEKFYVGQPRFLLLFYAMYNTLVARSEMVCYFVIILNHMVSASMITLLLPILIFLWAML
SVPRPSRRFWMMAIVYTEVAIVVKYFFQFGFFPWNKNAEV--NKDKPYHPPNIIGVEKKE
GYVLYDLIQLLALFFHRS--ILKCHGLWDEDDMTESGMDKEESDDEL---SLGHGRRDSS
---DSLKSINLAASVES-----------------VHVTFPEQQTAVRRKR--SSSNSEPS
QRSSFSSNRSQR-----GST-STRNSSQKG--SSVLSIK-----QKSKRELY-MEKLQEH
LIKAKAF----------------TIKKTLQIYVPIKQFFYNLIHPDYSAVTDVYVLMFLA
DTVDFIIIVFGFWAFGK-HSAAADITSSLSEDQVPGPFLVMVLIQFGTMVVDRALYLRKT
VLGKVIFQVILVFGIHFWMFFILPGVTERKFSQNLVAQLWYFVKCVYFGLSAYQIRCGYP
TRVLGNFLTKSYNYVNLFLFQGFR

PF12166 // ENSGT00390000013029_1_Domain_3 (2665, 3094)

LVPFLTELRAVMDWVWTDTTLSLSSWICVEDIYAHI
FILKCWRESEKRYPQPRGQKKKKVVKYGMGGMIIVLLICIVWFPLLFMSLIKSVAGVINQ
PLDVSVTITLGGYQPIFTMSAQQSQLKVMDQQNFNKFIQA-----FSRDTGAMQFLENYE
KEDITVAELEGNSNSLWTISPPSKQKMIHELLDPNSSFSVVFSWSIQRNLSLGAKSEIAT
DKLSFPLKNITRKNIAKMIAGNSTETSKTPVTIEKIYPYYVKAPSDSNSKPIKQLLS--E
NNFMDITI-------------ILSRDNTTKFNSEWWVLNLTGNRIYNPNSQALELVVFND
KVSPPSLGFLAGYGIMGLYASVVLVIGKFVREFFSGISHSIMFEELPNVDRILKLCTDIF
LVRETGELELEEDLYAKLIFLYRSPETMIKWTREKTN

----------MASEVVCGLIFRLLLPICLAVACAFRYNGLSFVYLIYLLLIPLFSEPTKT
T------MQGHTGRLLKSLCFTSLSFLLLHIIFHIT-----LASLEAQHRIAPGYNCSTW
EKTFRQIGF--ES-LKGADAGNGIRVFVPDIGMFIASLTIWLLCRNIVQKPVTDEGAQCN
LEFENEELAEGEKIDSEEALIYE-EDLDGGDGVEGELEESTKLKMFRRLASVASKLKEFI
GNMITTAGKVVVTILLGS-SGMMLPSLTSSVYFFVFLGLCTWWSWCRTFDPLLFSCLCVL
LAIFTAGHLIGLYLYQFQFFQEAVPPNDYYA-RLFGIKSVIQTDCSSTWKIIVNPDLSWY
HHANPILLLVMYYTLATLI-RIWLQEPL--VQDERTK------EEDRALACSPIQI-TAE
RRRSLWYATHYPTDERKLLSMTQDDYKPSDGLLVTVNGNPVDYHTIHPTLPMENGPGKAD
LYSTPQYRWEPSDESSEKPEE-EEEEKEEFEEERSREEKRSIKVHAMVSVFQFIMKQSYI
CALIAMM-AWSITYHSWLTFVLLIWSCTLWMIRNRRKYAMISSPFMVVYGNLLLILQYIW
SFELP--EIKKVPGFLEKKEPGELAS---------KILFTITFWLLLRQHLTEQKALQEK
EALLSEVKIGSQENEEK-----DEELQDIQV---EGEPKEK-------------------
-----EEEEEAKEEKQERKKAEEEE---VEEDDEQDIMKVLGNLVVAMFIKYWIYVCGGM
FFFVSFEGKIVMYKIIYMVLFLFCVALYQVHYEWWRKILKYFWMSVVIYTMLVLIFIYTY
QFENFPGLWQNMTGLKKEKLEDLGLKQFTVAELFTRIFIPTSFLLVCILHLHYFHDRFLE
LTDLKSIPSKEDNTIYSHAKVNGRVYLIINSIKKKLPIHQNELAHPEGSLPDLTMMHLTT
SLEKPEVRKLAEPGEEKPEGYSEKAR--KGELGKDSEESEEDGE-EE-----EESEEEEE
ETSDLRNKWHLVIDRLTVLFLKFLEYFHKLQVFMWWILELHIIKIVSSYIIWVSVKE--V
SLFNYVFLISWAFALPYAKLRRLASSVCTVWTCVIIVCKMLYQLQTIKPENFSVNCSLPN
ENQTNIP-LNELNKSLLYSAP-IDPTEWVGLRKSSPLLVYLRNNLLMLAILAFEVTIYRH
QEYYRGRNNLTAPVSKTIFHDITRLHLDDGLVNCAKYFINYFFYKFGLETCFLLSVNVIG
QRMDFYAMVHACWLIAVLYRRRRKAIAEIWPKYCCFLACIITFQYFICIGIPPAPCRDYP
WRFKGASFNDNIIKWLYFPDFIVRPNPVFLVYDFMLLLCASLQRQIFEDENKAAVRIMAG
DNVEICMNLDAASFSQHNPVPDFIHC-RSYLDMSKVIVFSYLFWFVLTIIFITGTTRISI
FCMGYLVACFYFLLFGGDLLLKPIKSILRYWDWLIAYNVFVITMKNILSIG

PF15917 // ENSGT00390000013029_1_Domain_0 (1492, 1775)

ACGYIGTLV
HNSCWLIQAFSLACTVKGYQ--------MPPANSPCTLPSGEAGIIWDSICFAFLLLQRR
VFMSYYFLHVVA--------DIKASQILASRGAELFQATIVKAVKARIEEEKKSMDQLKR
QMDRIKARQQKYKKGKERMLSLTQEPGEGQDMQKLSEEDDE-READKQKAKGKKKQWWRP
WVDHASMVRSGDYYLFETDSEEEEEEELKKEDEEPPRRSAF-------------------
--------------QFVYQAWITDPKTALRQRHK

ENSGT00390000013029_1_Linker_0_3 (1775, 2665)

EKKRSAREERKQRRKGSKEGP--VEW
EDREDEPIKKKSDGPDNIIKRIFNILKFTWVLFLATVDSFTTWLNSISREHIDISTVLRI
ERCMLTREIKKGN-VPTRESI-HMYYQNHI-MNLSRESGLDTIDEHPRAASGAQTAHRMD
SLD---SHDSIS------------------------------------------------
--------SEPTQCTMLYSRQGTTETIEEVEAEQEEEAGSTVPESGEAKEYE--------
-------AAGYDVGAMGAEEVSLTPE---EELTQFSTLDGDVEAPPSYSKAVSFEHLSFG
SQDD-STGKNHMAVSPDDSRTD-----KLGSSILPPLTHELTASELLLNKMFHDDE--LE
ESEKFYVGQPRFLLLFYAMYNTLVARSEMVCYFVIILNHMVSASMITLLLPILIFLWAML
SVPRPSRRFWMMAIVYTEVAIVVKYFFQFGFFPWNKTAEL--NKDKPYHPPNIIGVEKKE
GYVLYDLIQLLALFFHRS--ILKCHGLWDEDDMTESGMDKEESDDEL---SLSHGRRDSS
---DSLKSINLAASVES-----------------VHVTFPEQQTAVRRKR--SSTNSEPS
QRSSFSSNRSQR-----GST-STRNSSQKG--SSVLSIK-----QKSKRELY-MEKFQEH
LIKAKAF----------------TIKKTLQIYVPIKQFFYNLIHPDYSAVTDVYVLMFLA
DTVDFIIIVFGFWAFGK-HSAAADITSSLSEDQVPGPFLVMVLIQFGTMVVDRALYLRKT
VLGKVIFQVILVFGIHFWMFFILPGVTERKFSQNLVAQLWYFVKCVYFGLSAYQIRCGYP
TRVLGNFLTKSYNYVNLFLFQGFR

PF12166 // ENSGT00390000013029_1_Domain_3 (2665, 3094)

LVPFLTELRAVMDWVWTDTTLSLSSWICVEDIYAHI
FILKCWRESEKRYPQPRGQKKKKVVKYGMGGMIIVLLICIVWFPLLFMSLIKSVAGVINQ
PLDVSVTITLGGYQPIFTMSAQQSQLKVMDQQNFNKFIRA-----FSRDTGAMQFLENYE
KEDITVAELEGNSNSLWTISPPSKEKMIHELLDPNSSFSVVFSWSIQRNLSLGAKAEIAT
DKLSFTLQNSTRKNIAKMIAGNNTESSKTPVTIEKIYPYYVKAPSDSNSKPIKQLLS--E
NNFMDITI-------------ILSRDNTTKYNSEWWVLNLTGNRIYNPESQALELVVFND
KVSPPSLGFLAGYGIMGLYASVVLVIGKFVREFFSGISHSIMFEELPNVDRILKLCTDIF
LVRETGELELEEDLYAKLIFLYRSPETMIKWTREKTN

----------MASEVVCGLVFRLLLPICLAVACAFRYNGLSFVYLIYLLLIPLFSEPTKA
T------MQGHTGRLLKSLCFLSLSFLLLHIIFHIT-----LASLEAQHHITPGYNCSTW
EKTFRQIGFE---SLKGADAGNGIRVFVPDIGMFIASLTIWLVCRNIVQKPVTEEAAQYN
LEFENEELAAGEKADSEDALMDA---DADGDGAEGELEESAKLKMFRRVASVASKLKEFI
GNMITTAGKVVVTVLLGS-SGMMLPSLTSAVYFFVFLGLCTWWSWCRTFDPLLFSCLCVL
LAIFTAGHLIGLYLYQFQFFQEAVPPNDYYA-RLFGIKSVIQTDCSSTWKIVVNPELSWY
HHANPILLLVMYYTLATLI-RIWLQEPL--VQDEKTKE------EDRSLVCSSNQR-TAE
RKRNLWYAAQYPTDERKLLSMTQDDYKPSDGLLVTVNGNPVDYHTIHPSLPLENGPAKTD
LYSTPQYRWEPSEDSTEKKEE-EEDEKEEFEEERSQEEKRSVKVHAMVSVFQFIMKQSYI
CALIAMM-AWSITYHSWLTFVLLIWSCALWMIRNRRKYAMISSPFMVVYANLLLVLQYIW
SFELP--EIKKVPGFLEKKEPGELAS---------KILFTITFWLLLRQHLTEQKALQEK
EALLSEVKIGSQENEEK-----DEDLQDIQVE---GEPKEKEEEEEAQEEE---------
---------------------------QEDEDEDQDIMKVLGNLVVAMFIKYWIYVCGGM
FFFVSFEGKIVMYKIIYMVLFLFCVALYQVHYEWWRKILKYFWMSVVIYTMLVLIFIYTY
QFENFPGLWQNMTGLKKEKLEDLGLKQFTVAELFTRIFIPTSFLLVCILHLHYFHDRFLE
LTDLKSIPRKEDNTIYSHAKVNGRVYLIIN-----------RLAHPEGSLPDLAMMHLTA
SLERPEGKKLAELVDEKTEGSPGKAEK--GEL--GEGSEEPEEGEDEE-----EESEEEE
EMSDLRNKWHLVIDRLTVLFLKSLEHFHKLQVFTWWILELHIIKIVSSYIIWVSVKE--V
SLFNYVFLISWAFALPYAKLRRVASSICTVWTCVIIVCKMLYQLQTIKPESFSVNCSLPN
ENQTNIP-LQDLNKSLLYSAP-IDPTEWVGLRKSSPLLVYLRNNLLMLAILAFEVTIYRH
QEYYRGRNNLTAPVSKTIFHDITRMHLDDGLINCAKYFINYFFYKFGLETCFLMSVNVIG
QRMDFYAMIHACWLIAVLYRRRRKAIAEVWPKYCCFLACIITFQYFICIGIPPAPCRDYP
WRFKGADFNDNIIKWLYFPDFIVRPNPVFLVYDFMLLLCASLQRQIFEDENKAAVRIMAG
DNVEICMNLDAASFSQHNPVPDFIHC-RSYLDMSKVIIFSYLFWFVLTIIFITGTTRISI
FCMGYLVACFYFLLFGGDLLLKPIKSILRYWDWLIAYNVFVITMKNILSVSASQHSTD--
-----------AAS

PF15917 // ENSGT00390000013029_1_Domain_0 (1515, 1763)

TTRGFSSC----H-TAEDDASCRLPSGEAGIIWDSICFAFLLLQRR
VFMSYYFLHVVA--------DIKASQILASRGAELFQATIVKAVKARIEEEKRSMDQLKR
QMDRIKARQQKYKKGKERMLSLTQEAGEGQDVQNPPEEDDE-READKQKAKGKKKQWWRP
WVDHASMVRSGDYYLFETDSEEEEEEELKKEDEGPPRKSAF-------------------
--------------QVT---WR

ENSGT00390000013029_1_Linker_0_3 (1763, 2665)

TVPSILLSEKRLFA-------------KLHARA--VEW
EDREDEPVKKKSDGPDNIIKRIFNILKFTWVLFLATVDSFTTWLNSISREHIDISTVLRI
ERCMLTREIKKGN-VPTRESI-HMYYQNHI-MNLSRESGLDTLDERPGAAPGAQTAHRMD
SLD---SHDSISSCYTEATMLFSRQSTLDDLDGPDAVPKTSERARPRLRKMLSLDMSSSS
ADSGSLASSEPTQCTMLYSRQGTTETIEEVEAEAEEEVVG-PEEEEEEEEEA--------
-----EYDL-------GPEEASL--TPEEEECPQFSTDEGDVEAPPSYSKAVSFEHLSFG
-SQDDSGGKNHMMVSPDDS-----RTDKLESSILPPLTHELTASELLLNKMFHDDE--LE
ESERFYVGQPRFLLLFYAMYNTLVARSEMVCYFVIILNHMVSASMITLLLPILIFLWAML
SVPRPSRRFWMMAIVYTEVAIVVKYFFQFGFFPWNKNVEL--YKDKPYHPPNIIGVEKKE
GYVLYDLIQLLALFFHRS--ILKCHGLWDEDDIVDGGDQEESD-D---EPSFSHGRRDSS
---DSLKSINLAASVES-----------------VHVTFPEQPTTI--RRKRCGSSPQIS
PGSSFSSDRSKR-----GS-TSTRNSSQKG--SSVLSIK-----QKSKRELY-MEKLQE-
--------------Q-LVKAKAFTIKKTLQIYVPIRQFFYDLIHPDYSAVTDVYVLMFLA
DTVDFIIIVFGFWAFGK-HSAAADITSSLSEDQVPGPFLVMVLIQFGTMVVDRALYLRKT
VLGKVVFQVILVFGIHFWMFFILPVVTERKFSQNLVAQLWYFVKCVYFGLSAYQIRCGYP
TRVLGNFLTKSYNYVNLFLFQGFR

PF12166 // ENSGT00390000013029_1_Domain_3 (2665, 3094)

LVPFLTELRAVMDWVWTDTTLSLSSWICVEDIYAHI
FILKCWRESEKRYPQPRGQKKKKVVKYGMGGMIIVLLICIVWFPLLFMSLIKSVAGVINQ
PLDVSVTITLGGYQPIFTMSAQQSQLKVMDQTKFNKFMRT-----FSRDTGAMQFLENYE
KEDITVAELEGNSNSLWTISPPSKQKMISELKDLSSSFSVVFSWSIQRNMSLGAKAEIAT
DKLSFPLQNSTRKNIANMIASNDPESSKTPVTIERIYPYYVKAPSDSNSKPIKQLLS--E
SNFMNITI-------------ILSRDNSTNSNSEWWVLNLTGNRIYDQESQALELVVFND
KVSPPSLGFLAGYGIMGLYASVVLVIGKFVREFFSGISHSIMFEELPNVDRILKLCTDIF
LVRETGELELEEDLYAKLIFLYRSPETMIKWTREKTN

------------------------------------------------------------
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-------------SLKGADAGNGIRVFVPDIGMFITSLTIWLVCRNIVQKPMTEATTQYN
LEFENEELTGGQKIDSEEALICE-EDLDGGDSGEGELEESTKLKIFRRLASVASKLKEFI
GNMITTAGKVVVTILLGS-SGMMLPSLTSSVYFFVFLGLCTWWSWCQTFDPLLFSCLCVL
LAIFTAGHLIGLYLYQFQFFQEVVPPNDYYASRLFGIKSVIQTDCSSTWKIIVNPDLSWY
HYANPILLLVMYYTLATLI-RIWLQEPL--VQDGRPKE------EDRALACSPIQI-TAE
RRRSLWYATHYPTDERKLLPMTQDDYKPSDGLLVTVNGNPVDYHTIHPSLPVENGPGKAD
LYSTPQYRWEPSEASSEKKED-KEEEKEEFEEERSHEEKRSIKVHAMVSVFQFIMKQSYI
CALIAMMEAWSITYHSWLTFVLLIWSCTLWMIRNRRKYAMISSPFMVVYGNLLLVLQYIW
SFELP--EIKKVPGFLEKKEPEELAS---------KILFTITFWLLLRQHLTEQKALQGK
EALLSEVKIGNQENEEK-----ED-EELQDIQ---EEPRVQEEEDEAQEEKQE-------
-------------------KKMEEKEEEEEEEDDQDIMKVLGNLVVAMFIKYWIYVCGGM
FFFVSFEGKIVMYKIIYMVLFLFCVALYQVHYEWWRRILKYFWMSVVIYTMLVLIFIYTY
QFENFPGLWQNMTGLKKEKLEDLGLKQFTVAELFTRIFIPTSFLLVCILHLHYFHDRFLE
LTDLKSIPSKEDNTIYSHAKVNGRVYLIIN-----------RLAHPEGSLPDLTMMNLSA
SLEK---RKFSEPGEEKPEGFSEEVEK--DEL--GKDSEESEEDEEEEE------SEEEE
ETSDLKNKWHLVIDRLTVLFLKFLEYFHKLQVFMWWILELHIIKIVSSYIIWVSVKE--V
SLFNYVFLISWAFALPYAKLRRLASSICTVWTCVIIVCKMLYQLQTIKPENFSVNCSLPN
ENQTNIL-LQDLNKSLLYSAP-IDPTEWVGLRKSSPLLVYLRNNLLMLAILAFEVTIYRH
QEYYRGRNNLTAPVSKTIFHDITRLHLDDGIINCAKYFINYFFYKFGLETCFLLSVNVIG
QRMDFYAMIHACWLIAVLYRRRRKAIAEVWPKYCCFLACIITFQYFICIGIPPAPCRDYP
WRFKGASFNDNIIKWLYFPDFIVRPNPVFLVYDFMLLLCASLQRQIFEDENKAAVRIMAG
DNVEICMNLDAASFSQHNPVPDFIHC-RSYLDMSKVIIFSYLFWFVLTIIFITGTTRISI
FCMGYLVACFYFLLFGGDLLLKPIKSILRYWDWLIAYNVFVITMKNILSIGACGYITTLV
KNSCWFIQAFSLACTVKGYQM--------PDGNSPCTLPSGEAGIIWDSICFAFLLLQRR
VFMSYYFLHVVA--------DIKASQILASRGAELFQATVVKAVKARIEEEKKSMDQLKR
QMDRIKARQQKYKKGKERMLSLTQESGEGQDIQKLSEEDDE-READKQKAKGKKKQWWRP
WVDHASMVRSGDYYLFETDSEEEEEEELKKEDEELPRRSAF-------------------
--------------QFVYQAWITDPKTALRQRRKEKKRSAGEDQEQKRKGSGEGP--MEW
DDREEEHVKKKSDGPDNIIKRIFNILKFTWVLFLATVDSFTTWLNSISREHIDISTVLRI
ERCMLTREIKKGN-VPTRESI-HMYYQNHM-MNLSRESGLDTIDERPGAASGAQTAHRMD
SLD---SHDSISSCYTEATMLFSRQSTLDDLDGPETVPKTSERARPRLRKMFSMDVSSSS
ADSGSLASSEPTQCTMLYSRQGTTETIEEVEAEQEEEAGS-TVPEPQ-EVAT--------
-----EYEVEYEVGTLDTVEVGL--TP-EEELTQFSTVDGDVEVPPSYSKAVSFEHLSLG
-SQEDYTCQNHMVVSPDDSRPDDSRMDKLESSILAPLTHELTASELLLNKMFRDDE--LE
ESEKFYTEQPRFLLLFYAMYNTLVARSEMVCYFVIILNHMVSASVITLLLPILIFLWAML
SVPRPSRRFWMMAIVYTEVAIVVKYFFQFGFFPWNKQWEL--YKDKPYHPANIIGVEKKE
GYVLYDLIQLLALFFHRS--ILKCHGLWDEDDIVESDSEGADSGDDFCLT---SGRRDSY
---NSLKSINLAASVE--------S---------VHVTFPEQQ-MAIR-RKCSANSSQIS
ERSSFSSNRSKR-----GS-TSTRNSSQKG--SSVLSIK-----QKSKRELY-TEKLQE-
--------------H-LIRAKAFTIKKTLKIYVPIRQFFYNLIHPEYSAVTDVYVLMFLA
DTVDFIIIVFGFWAFGK-HSAAADITSSLSEDQVPGPFLVMVLIQFGTMVVDRALYLRKT
VLGKVIFQVILVFGIHFWMFFILPSVTERKFSQNLVAQLWYFVKCVYFGLSAYQIRCGYP
TRVLGNFLTKSYNYVNLFLFQGF

PF12166 // ENSGT00390000013029_1_Domain_3 (2664, 3095)

RLVPFLTELRAVMDWVWTDTTLSLSSWICVEDIYAHI
FILKCWRESEKRYPQPRGQKKKKVVKYGMGGMIIVLLICIVWFPLLFMSLIKSVAGVINQ
PLDVSVTITLGGYQPIFTMSAQQSQLKVMDQPKFNKFIRE-----FSRDTGAMQFLENYE
KEDITVAELEGNSNSLWTISPPSKQKMIHELMDSNSSFSVVFSWSIQRNISLGAKSEIAT
DKLSFPLKNITRESIAKMIAGNNTESSKTPVTIEKIYPYYVKAPSDSNSKPIKQLLS--E
NNFMDITI-------------ILSRDNTTKSNSEWWVLNLTGNRLYNQHSQALELVVFND
KVSPPSLGFLAGYGIMGLYASVVLVIGKFVREFFSGISHSIMFEELPNVDRILKLCTDIF
LVRETGELELEEDLYAKLIFLYRSPETMIKWTREKTN

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--------MEKLQEH-LIKAKAFTIKKTLQIYVPIRQFFYDLIHPDYSAVTDVYVLMFLA
DTVDFIIIVFGFWAFGK-HSAAADITSSLSEDQVPGPFLVMVLIQFGTMVVDRALYLRKT
VLGKVIFQVILVFGIHFWMFFILPSVTERKFSQNLVAQLWYFVKCVYFGLSAYQIRCGYP
TRVLGNFLTKSYNYVNLFLFQGFR

PF12166 // ENSGT00390000013029_1_Domain_3 (2665, 3094)

LVPFLTELRAVMDWVWTDTTLSLSSWICVEDIYAHI
FILKCWRESEKRYPQPRGQKKKKVVKYGMGGMIIVLLICIVWFPLLFMSLIKSVAGVINQ
PLDVSVTITLGGYQPIFTMSAQQSQLKIMEQPKFNTFMRS-----FSTNTGAMQFLENYE
REDITVAELEGNSNSLWTISPPSKQKMIQELIDFNSSFSLVLSWSIQRNMTLGAKAEIAT
DKLSFLLKNNTRKNIAKMIAGNDTESSNTPVTIEKIYPYYVKAPSDSNSKPIKQLLS--E
NNFMNITI-------------ILSRDNVTTSNSEWWVLNLTGSRIYNQESQALELVVFND
KVSPPSLGFLAGYGIMGLYASVVLVIGKFVREFFSGISHSIMFEELPNVDRILKLCTDIF
LVRETGELELEEDLYAKLIFLYRSPETMIKWTREKTN

----------MASEVVCGLVFRLLLPICLAVACAFRYNGLSFVYLIYLLLIPLFSEPTKA
T------MQGHTGRLLKSLCFTSLSFLVLHIIFHIT-----LASLEAQHRITPGYNCSTW
EKTFRQIGFE---SLKGADAGNGIRVFVPDIGMFIASLTIWLVCRNIVQKPEMEEAGQYN
SECENEELPGGEKMDPEDALIYE-EDFDGEEGVEGELEESTKLKLFRRLASVASKLKEFI
GNMITTAGKVVVTILLGS-SGMMLPSLTSAVYFFVFLGLCTWWSWCRTFDPLLFSCLCVL
LAIFTAGHLVGLYLYQFQFFQEAVPPNDYYA-RLFGIKSVIQTDCSSTWKIIVNPELSWY
HHANPILLLVMYYTLATLI-RIWLQEPL--VQDERTK------EDDGALDCSSNMN-IAE
RRRSLWYATHYPTDERKLLSMTQDDYKPSDGLLMTVNGNPVDYHTIHPSLPIENGPAKAD
LYSTPQYRWEPAEESTEKKE-EDEDKKEDSEAERSLEEKRSVRIHAMVTVFQFIMKQSYI
CALIAMM-AWSITYHSWLTFVLLIWSCTLWMIRNRRKYAMISSPFMVVYGNLLLVLQYIW
SFELP--EIRKVPGFLEKKEPGELAS---------KILFTITFWLLLRQHLTEQKALQEK
RALLSEVKIGSEEHEEK----EDEELQDMQVE---GEPREKEEEEE--------------
----------------------------VEEDDDQDIMKVLGNLVVALFIKYWIYVCGGM
FFFVSFEGKIVMYKIIYMVLFLFCVALYQVHYEWWRKILKYFWMSVVIYTMLVLIFIYTY
QFENFPGLWQNMTGLKKEKLEDLGLKQFTVAELFTRIFIPTSFLLVCILHLHYFHDRFLE
LTDLKSIPSKEDNTIYR-------------------------LAHPEGSLPDLAIMNLTT
SLDKPDVQKLVEPGEERLEECSKEEEKGEPEK--DSE-----ES-EEEEDE-EEES-EEE
ESSDLRNKWHLVIDRLTVLFLKFLEYFHKLQVFMWWILELHIIKIVSSYIIWVT-V-KEV
SLFNYVFLISWAFALPYAKLRRVASSVCTVWTCVIIVCKMLYQLQTIKPENFSVNCSLPN
ENQTNIPL-NELNKSLLYSAP-VDPTEWVGLRKSSPLLVYLRNNLLMLAILAFEVTIYRH
QEYYRGRNNLTAPVSKTIFHDITRLHLDDGIINCAKYFINYFFYKFGLETCFLMSVNVIG
QRMDFYAMIHACWLIGVLYRRRRKAIAEVWPKYCCFLACIITFQYFICIGIPPAPCKDYP
WRFKGANFNDNIIKWLYFPDFIVRPNPVFLVYDFMLLLCASLQRQIFEDENKAAVRIMAG
DNVEICMNLDAASFSQHNPVPDFIHC-RSYLDMSKVVIFSYLFWFVLTIIFITGTTRISI
FCMGYLVACFYFLLFGGDLLLKPIKSILRYWDWLIAYNIFVITMKNILSIG

PF15917 // ENSGT00390000013029_1_Domain_0 (1492, 1771)

ACGYIGALV
KNSCWLIQAFSLACTVKGYKMPD--------EDSKCKLPSGEAGIIWDSICFAFLLLQRR
VFMSYYFLHVVA--------DIKASQILASRGAELFQATIVKAVKARIEEEKKSMDQLKR
QMDRIKARQQKYKKGKERMLSLTQESGEGQDIQKVSEDDDE-READKQKAKGKKKQWWRP
WVDHASMVRSGDYYLFETDSEEEEEEELKKEDEEPPRKSAF-------------------
--------------QFVYQAWITDPKTALRQ-----------------------------
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----------MASEVVCGLIFRLLLPICLAVACAFRYNGLSFVYLIYLLLIPLFSEPTKA
T------MQGHTGRLLQSLCITSLSFLLLHIIFHIT-----LASLEAQHRITPAYNCSTW
EKTFRQIGFE---SLKGADAGNGIRVFVPDIGMFIASLTIWLVCRTIVKKPDTEEIAQLN
SECENEELAGGEKMDSEEALIYE-EDLDGEEGMEGELEESTKLKILRRFASVASKLKEFI
GNMITTAGKVVVTILLGS-SGMMLPSLTSAVYFFVFLGLCTWWSWCRTFDPLLFGCLCVL
LAIFTAGHLIGLYLYQFQFFQEAVPPNDYYA-RLFGIKSVIQTDCASTWKIIVNPDLSWY
HHANPILLLVMYYTLATLI-RIWLQEPL--VQEEMAK------EDEGALDCSSNQN-TAE
RRRSLWYATQYPTDERKLLSMTQDDYKPSDGLLVTVNGNPVDYHTIHPSLPIENGPAKTD
LYTTPQYRWEPSEESSEKKEE-EEDKREDSEGEGSQEEKRSVRMHAMVAVFQFIMKQSYI
CALIAMM-AWSITYHSWLTFVLLIWSCTLWMIRNRRKYAMISSPFMVVYANLLLVLQYIW
SFELP--EIKKVPGFLEKKEPGELAS---------KILFTITFWLLLRQHLTEQKALREK
EALLSEVKIGSQELEEK----EDEELQDVQV---EGEPTE--------------------
--KEEEEEEEIKE---ERHEVKKEEEEEVEEDDDQDIMKVLGNLVVALFIKYWIYVCGGM
FFFVSFEGKIVMYKIIYMVLFLFCVALYQVHYEWWRKILKYFWMSVVIYTMLVLIFIYTY
QFENFPGLWQNMTGLKKEKLEDLGLKQFTVAELFTRIFIPTSFLLVCILHLHYFHDRFLE
LTDLKSIPSKEDNTIYSHAKVNGRVYLIIN-----------RLAHPEGSLPDLAIMNMTA
SLDKPEVQKLAESGEERPEECVKKTE--KGEAGKDSDESEEEED-EE-------EESEEE
ESSDLRNKWHLVIDRLTVLFLKFLEYFHKLQVFMWWILELHIIKIVSSYIIWVTVKE--V
SLFNYVFLISWAFALPYAKLRRAASSVCTVWTCVIIVCKMLYQLQTIKPENFSVNCSLPN
ENQTNIP-LHELNKSLLYSAP-VDPTEWVGLRKSSPLLVYLRNNLLMLAILAFEVTVYRH
QEYYRGRNNLTAPVSKTIFHDITRLHLDDGLINCAKYFVNYFFYKFGLETCFLMSVNVIG
QRMDFYAMIHACWLIGVLYRRRRKAIAEVWPKYCCFLACIITFQYFVCIGIPPAPCRDYP
WRFKGAYFNDNIIKWLYFPDFIVRPNPVFLVYDFMLLLCASLQRQIFEDENKAAVRIMAG
DNVEICMNLDAASFSQHNPVPDFIHC-RSYLDMSKVIIFSYLFWFVLTIIFITGTTRISI
FCMGYLVACFYFLLFGGDLLLKPIKSILRYWDWLIAYNVFVITMKNILSIG

PF15917 // ENSGT00390000013029_1_Domain_0 (1492, 1775)

ACGYIGALV
RNSCWLIQAFSLACTVKGYQ--------MPEDDSRCKLPSGEAGIIWDSICFAFLLLQRR
VFMSYYFLHVVA--------DIKASQILASRGAELFQATIVKAVKARIEEEKKSMDQLKR
QMDRIKARQQKYKKGKERMLSLTQESGEGQDIQKVSEEDDE-READKQKAKGKKKQWWRP
WVDHASMVRSGDYYLFETDSEEEEEEELKKEDEEPPRKSAF-------------------
--------------QFVYQAWITDPKTALRQRRK

ENSGT00390000013029_1_Linker_0_3 (1775, 2665)

EKKKLAREEQKERRKGSGDGP--VEW
EDREDEPVKKKSDGPDNIIKRIFNILKFTWVLFLATVDSFTTWLNSISREHIDISTVLRI
ERCMLTREIKKGN-VPTRESI-HMYYQNHI-MNLSRESGLDTIDEHSGAGSRAQAAHRMD
SLD---SRDSISSCYTEATLLISRQSTLDDLDGQDPVPKTSERARPRLRKMFSLDMSSSS
ADSGSVASSEPTQCTMLYSRQGTTETIEEVEAEAEEEVVEGLEPELHDAEEK--------
-----EYAAE---YEAGVEEISLTPD---EELPQFSTDDCDVEAPPSYSKAVSFEHLSFA
SQDD-SGAKNHMVVSPDDSRTD-----KLESSILPPLTHELTASDLLMSKMFHDDE--LE
ESEKFYVDQPRFLLLFYAMYNTLVARSEMVCYFVIILNHMTSASIITLLLPILIFLWAML
SVPRPSRRFWMMAIVYTEVAIVVKYFFQFGFFPWNKDLEI--YKERPYFPPNIIGVEKKE
GYVLYDLIQLLALFFHRS--ILKCHGLWDEDDIVDSNTDKEGSDDEL---SLDQGRRGSS
---DSLKSINLAASVES-----------------VHVTFPEQPAAIRRKR--SCSSSQIS
PRSSFSSNRSKR-----GST-STRNSSQKG--SSVLSLK-----QKSKRELY-MEKLQEH
LIKAKAF----------------TIKKTLQIYVPIRQFFYDLIHPDYSAVTDVYVLMFLA
DTVDFIIIVFGFWAFGK-HSAAADITSSLSEDQVPGPFLVMVLIQFGTMVVDRALYLRKT
VLGKVIFQVILVFGIHFWMFFILPGVTERKFSQNLVAQLWYFVKCVYFGLSAYQIRCGYP
TRVLGNFLTKSYNYVNLFLFQGFR

PF12166 // ENSGT00390000013029_1_Domain_3 (2665, 3094)

LVPFLTELRAVMDWVWTDTTLSLSSWICVEDIYAHI
FILKCWRESEKRYPQPRGQKKKKAVKYGMGGMIIVLLICIVWFPLLFMSLIKSVAGVINQ
PLDVSVTITLGGYQPIFTMSAQQSQLKVMDNSKYNEFLKS-----FGPNSGAMQFLENYE
REDVTVAELEGNSNSLWTISPPSKQKMIQELTDPNSCFSVVFSWSIQRNMTLGAKAEIAT
DKLSFPLAVATRNSIAKMIAGNDTESSNTPVTIEKIYPYYVKAPSDSNSKPIKQLLS--E
NNFMNITI-------------ILFRDNVTKSNSEWWVLNLTGSRIFNQGSQALELVVFND
KVSPPSLGFLAGYGIMGLYASVVLVIGKFVREFFSGISHSIMFEELPNVDRILKLCTDIF
LVRETGELELEEDLYAKLIFLYRSPETMIKWTREKTN

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--------------------------------MTESGMDKEESDDEL---SLGHGRRDSS
---DSLKSINLAASVES-----------------VHVTFPEQQTAVRRKR--SSSNSEPS
QRSSFSSNRSQR-----GST-STRNSSQKG--SSVLSIK-----QKSKRELY-MEKLQEH
LIKAKAF----------------TIKKTLQIYVPIKQFFYNLIHPDYSAVTDVYVLMFLA
DTVDFIIIVFGFWAFGK-HSAAADITSSLSEDQVPGPFLVMVLIQFGTMVVDRALYLRKT
VLGKVIFQVILVFGIHFWMFFILPGVTERKFSQNPGPS-LVLVKCVYFGLICLPRPFLLP
-NAPGNFLTKEQLYV---FPTRFR

PF12166 // ENSGT00390000013029_1_Domain_3 (2665, 2867)

LVPFLTELRAVMDWVWTDTTLSLSSWICVEDIYAHI
FILKCWRESEKRYPQPRGQKKKKVVKYGMGGMIIVLLICIVWFPLLFMSLIKSVAGVINQ
PLDVSVTITLGGYQPIFTMSAQQSQLKVMDQQNFNKFIQA-----FSRDTGAMQFLENYE
KEDITVAELEGNSNSLWTISPPSKQKMIHELLDPNSSFSVVFSWSIQ-------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------

----------MASEVVCGLVFRLLLPICLAVACAFRYNGLSFVYLIYLLLIPLFSEPTKT
T------MQGHTGRLLQSLCITSLSFLLLHIIFHIT-----LASLEAQHRIAPAYNCSTW
EKTFRQIGFE---SLKGADAGNGIRVFVPDIGMFIASLTIWLVCRNIVKKPDTDEVAQFN
PDCENEELAGGEKMDSEEALIYE-EDLDGEEGMEGELEESTKLKMFRRLASVASKLKEFI
GNMITTAGKVVVTILLGS-SGMMLPSLTSAVYFFVFLGLCTWWSWCRTFDPLLFGCLCVL
LAIFTAGHLIGLYLYQFQFFQEAVPPNDYYA-RLFGIKSVIQTDCSSTWKIIVNPELSWY
HHANPILLLVMYYTLATLI-RIWLQEPL--VQDEMAK------EEEGTLDCSSNQN-TAE
RRRSLWYATQYPTDERKQSL-LSSFLLPWQGLLVTVNGNPVDYHTIHPSLPLENGPAKTD
LYTTPQYRWDASEESSEKKEE-DEDKKEDSEGEGSQEEKRSVRIHAMVTVFQFIMKQSYI
CALIAMM-AWSITYHSWLTFVLLIWSCTLWMIRNRRKYAMISSPFMVVYANLLLVLQYIW
SFELP--EIKKVPGFLEKKEPGELAS---------KILFTITFWLLLRQHLTEQKALQEK
EALLSEVKIGSQELEE----REEEEEEEEEE---EEEEEEEEEEEEEEEEEEEEEEEEEE
EEEEEEEEEEIKE---ERHELKKEEEEEVEEDDDQDIMKVLGNLVVALFIKYWIYVCGGM
FFFVSFEGKIVMYKIIYMVLFLFCVALYQVHYEWWRKILKYFWMSVVIYTMLVLIFIYTY
QFENFPGLWQNMTGLKKEKLEDLGLKQFTVAELFTRIFIPTSFLLVCILHLHYFHDRFLE
LTDLKSIPSKEDNTIY-------------------------RLAHPEGSLPDLAIMNMTA
SLDKPEGQKLVEPGEERPEECAKKAE--KGEPGKDSDESEEEED-EE-------EESEEE
ETSDLRNKWLLVIDRLTVLFLKFLEYFHKLQVFMWWILELHIIKIVSSYIIWVTVKE--V
SLFNYVFLISWAFALPYAKLRRVASSVCTVWTCVIIVCKMLYQLQTIKPENFSVNCSLPN
ENQTNIP-LNELNKSLLYSAP-VDPTEWVGLRKSSPLLVYLRNNLLMLAILAFEVTIYRH
QEYYRGRNNLTAPVSKTIFHDITRLHLDDGLINCAKYFINYFFYKFGLETCFLMSVNVIG
QRMDFYAMVHACWLIGVLYRRRRKAIAEVWPKYCCFLACIITFQYFVCIGIPPAPCRDYP
WRFKGANFNDNIIKWLYFPDFIVRPNPVFLVYDFMLLLCASLQRQIFEDENKAAVRIMAG
DNVEICMNLDAASFSQHNPVPDFIHC-RSYLDMSKVIIFSYLFWFVLTIIFITGTTRISI
FCMGYLVACFYFLLFGGDLLLKPIKSILRYWDWLIAYNVFVITMKNILSIG

PF15917 // ENSGT00390000013029_1_Domain_0 (1492, 1775)

ACGYIGALV
RNSCWLIQAFSLACTVKGYK--------MPEDDSKCKLPSGEAGIIWDSICFAFLLLQRR
VFMSYYFLHVVA--------DIKASQILASRGAELFQATIVKAVKARIEEEKKSMDQLKR
QMDRIKARQQKYKKGKERMLSLTQESGEGQDIQKLSEEDDE-READKQKAKGKKKQWWRP
WVDHASMVRSGDYYLFETDSEEEEEEELKKEDEEPPRKSAF-------------------
--------------QFVYQAWITDPKTALRQRRK

ENSGT00390000013029_1_Linker_0_3 (1775, 2665)

EKKKLAREEQKGRRKGSGEGP--VEW
EDREDGPIKKKSDGPDNIIKRIFNILKFTWVLFLATVDSFTTWLNSISREHIDISTVLRI
ERCMLTREIKKGN-VPTRESI-HMYYQNHI-MNLSRESGLDTIDEHPGADSRAQAAHRMD
SLD---SHDSISSCYTEATLLISRQSTLDDLDGQDSVPKTSERARPRLRKMVSMDMSSSS
ADSGSVASSEPTQCTMLYSRQGTTETIEEVEAEAEEEVVEGLESELHDAEDK--------
-----EYVAD---YEAEVEEVSLTPD---EELPQFSTDDGDVEAPPSYSKAVSFEHLSFA
SQDD-SGAKNHMVVSPDDSRTD-----KLESSILPPLTHELTASELLMNKMFHDDE--LE
ESEKFYVDQPRFLLLFYAMYNTLVARSEMVCYFVIILNHMISASIITLLLPILIFLWAML
SVPRPSRRFWMMAIVYTEVAIVVKYFFQFGFFPWNKELEL--NKDKPYFPPNIIGVEKKE
GYVLYDLIQLLALFFHRS--ILKCHGLWDEDDVVDSGTDKEESDDEL---SMDHSRRGSS
---DSLKSINLAASVES-----------------VHVTFPEQPGAIRRKR--SCSSSQIS
PQSSFSSNRSKR-----GST-STRNSSQRG--SSVLSIK-----QKSKRELY-MEKLQEH
LIKAKAF----------------TIKKTLQIYVPIRQFFYDLIHPDYSAVTDVYVLMFLA
DTVDFIIIVFGFWAFGK-HSAAADITSSLSEDQVPGPFLVMVLIQFGTMVVDRALYLRKT
VLGKVIFQVILVFGIHFWMFFILPSVTERKFSQNLVAQLWYFVKCVYFGLSAYQIRCGYP
TRVLGNFLTKSYNYVNLFLFQGFR

PF12166 // ENSGT00390000013029_1_Domain_3 (2665, 3094)

LVPFLTELRAVMDWVWTDTTLSLSSWICVEDIYAHI
FILKCWRESEKRYPQPRGQKKKKAVKYGMGGMIIVLLICIVWFPLLFMSLIKSVAGVINQ
PLDVSVTITLGGYQPIFTMSAQQSQLKIMDGAKYKAFLKS-----FATNTGAMQFLENYE
KEDITVAELEGNSNSLWTISPPSKQKMIQELTDPSSSFSVVFSWSIQRNMTLGAKAEIAT
DKLSFPLASETRNNIAKMIAGNDTESSNTPVTIERIYPYYVKAPSDSNSKPIKQLLS--E
SNFMNITI-------------ILFRDNVTKSNSEWWVLNLTGNRIYNQGSQALELIIFND
KVSPPSLGFLAGYGIMGLYASVVLVIGKFVREFFSGISHSIMFEELPNVDRILKLCTDIF
LVRETGELELEEDLYAKLIFLYRSPETMIKWTREKTN

---------------------------MLATQYTASYSHVHFPWT-----PPKITDGVCI
TFPDRSLLLPQLETFLLSTSLSGLCCLLYHICFTIS-----V------------------
---ITTNAI---SVLKGADAGNGIRVFVPDIGMFIASLTIWLVCRNIVQKPMIEEAAQYN
PEFENEELTGGEKIDSEEALIYE-EDLDGGDGGEGELEESTKLKIFRRLASVASKLKEFI
GNMITTAGKVVVTILLGS-SGMMLPSLTSSVYFFVFLGLCTWWSWCRTFDPLLFSCLCVL
LAIFTAGHLIGLYLYQFQFFQEAVPPNDYYA-RLFGIKSVIQTDCSSTWKIIVNPELSWY
HHANPILLLVMYYTLATLI-RIWLQEPL--VQDERPR------EEDRALACSPIQI-TAE
RRRSLWYATHYPTDERKLLSMTQDDYKPSDGLLVTVNGNPVDYHTIHPSLPMENGPGKAD
LYSTPQYRWEPSDESSEKKDE-EEEEKAEFEEEQSHEEKRSVKVHAMVSVFQFIMKQSYI
CALIAMM-AWSITYHSWLTFVLLIWSCTLWMIRNRRKYAMISSPFMVVYGNLLLILQYIW
SFELP--EIKKVPGFLEKKDPGELAS---------KILFTITFWLLLRQHLTEQKALREK
EALLSEVKIGSQENEEK-----DEELQDIQV---EGEPREK-------------------
-----EEEEEAKEETPERKKEEKEE--EEEEEDDQDIMKVLGNLVVAMFIKYWIYVCGGM
FFFVSFEGKIVMYKIIYMVLFLFCVALYQVHYEWWRRILKYFWMSVVIYTMLVLIFIYTY
QFENFPGLWQNMTGLKKEKLEDLGLKQFTVAELFTRIFIPTSFLLVCILHLHYFHDRFLE
LTDLKSIPSKEDNTIYR-------------------------LAHPEGSLPDLTMINLTA
SLEKPEVRRLAEPREEKPEGCSEKAE--KGELGKDSEESEDGE--------EEEESEEEE
ETSDLRNKWHLVIDRLTVLFLKFLEYFHKLQVFMWWILELHIIKIVSSYIIWVSVKE--V
SLFNYVFLISWAFALPYAKLRRLASSVCTVWTCVIIVCKMLYQLQTIKPENFSVNCSLPN
ENQTNIP-LQDLNKSLLYNSS-IDPTEWVGLRKSSPLLVYLRNNLLMLAILAFEVTIYRH
QEYYRGRNNLTAPVSKTIFHDITRLHLDDGLINCAKYFINYFFYKFGLETCFLMSVNVIG
QRMDFYAMIHACWLIAVLYRRRRKAIAEVWPKYCCFLACIITFQYFICIGIPPAPCRDYP
WRFKGASFNDNIIKWLYFPDFIVRPNPVFLVYDFMLLLCASLQRQIFEDENKAAVRIMAG
DNVEICMNLDAASFSQHNPVPDFIHC-RSYLDMSKVIIFSYLFWFVLTIIFITGTTRISI
FCMGYLVACFYFLLFGGDLLLKPIKSILRYWDWLIAYNVFVITMKNILSIG

PF15917 // ENSGT00390000013029_1_Domain_0 (1492, 1775)

ACGYIGTLV
KNSCWLIQAFSLACTVKGYK--------MPDDDSPCKLPSGEAGIIWDSICFAFLLLQRR
VFMSYYFLHVVA--------DIKASQILASRGAELFQATIVKAVKARIEEEKKSMDQLKR
QMDRIKARQQKYKKGKERMLSLTQEPGEGQDTRKFSEEDDE-READKQKAKGKKKQWWRP
WVDHASMVRSGDYYLFETDSEEEEEEELKKEDEELPRRSAF-------------------
--------------QFVYQAWITDPKTALRQRRK

ENSGT00390000013029_1_Linker_0_3 (1775, 2665)

EKKRSAREEQKRKRKGSGEGA--VEW
DDREQERVKKKSDGPDNIIKRIFNILKFTWVLFLATVDSFTTWLNSISREHIDISTVLRI
ERCMLTREIKKGN-VPTRESI-HMYYQNHI-MNLSRESGLDTIDERPGAASGAQTAHRMD
SLD---SHDSIS------------------------------------------------
--------SEPTQCTMLYSRQGTTETIEEVEAEQEEEARGTAPEPGEA-TEYEAE-----
------YQAEYEAGALGAEEAGVTPE---EELAQFSTVDGDVEVPPSYSKAVSFEHLSFG
SQDD-STGKNHMVVSPDDSRTD-----KLESSILPPLTHELTASELLLNKMFHDDE--LE
ESEKFYTEQPRFLLLFYAMYNTLVARSEMVCYFVIILNHMVSASMITLLLPILIFLWAML
SVPRPSRRFWMMAIVYTEVAIVVKYFFQFGFFPWNKHVEL--HKDKPYHAPNIIGVEKKE
GYVLYDLIQLLALFFHRS--ILKCHGLWDEDDIVESRSDKEDSDDEL---SLARGRRDSS
---DSLKSINLATSVES-----------------VHVTFPEQHTAVRRKC--SGSSSQIS
QRSSFSSNRSKR-----GST-STRNSSQKG--SSVLSIK-----QKSKREFY-MEKLQEH
LIKAKAF----------------TIKKTLQIYVPIRQFFYNLIHPEYSAVTDVYVLMFLA
DTVDFIIIVFGFWAFGK-HSAAADITSSLSEDQVPGPFLVMVLIQFGTMVVDRALYLRKT
VLGKVIFQVILVFGIHFWMFFILPGVTERKFSQNLVAQLWYFVKCVYFGLSAYQIRCGYP
TRVLGNFLTKSYNYVNLFLFQGFR

PF12166 // ENSGT00390000013029_1_Domain_3 (2665, 3094)

LVPFLTELRAVMDWVWTDTTLSLSSWICVEDIYAHI
FILKCWRESEKRYPQPRGQKKKKVVKYGMGGMIIVLLICIVWFPLLFMSLIKSVAGVINQ
PLDVSVTITLGGYQPIFTMSAQQSQLKVMDQSTFNTFIKN-----FSRDTGAMQFLENYE
KEDITVAELEGNSNSLWTISPPSKQKMIHELTDPNSSFSVVFSWSIQRNLSLGAKSEIAT
DKLSFPLKNITRESIAKMIAGNNTESSKTPVTIEKIYPYYVKAPSDSNSKPIKQLLS--E
NNFMDITI-------------ILSRDNTTKSNSEWWVLNLTGNRIYNQHSQALELVVFND
KVSPPSLGFLAGYGIMGLYASVVLVIGKFVREFFSGISHSIMFEELPNVDRILKLCTDIF
LVRETGELELEEDLYAKLIFLYRSPETMIKWTREKTN

------------------------------------------------------------
M------LLFSKCRLSENMCFILYKEL-SQTLFHIYY----LTSLE--------------
-------QNKEGKYLKGADAGNGIRVFAPDIGMFIASLTIWLLCRNIVQKPVTDEAAQSN
LEFENEELAGGEKIDSEEALIYE-EDLDGGDGVEGELEESTRLKMFRRLACVASKLKEFI
GNMITTAGKVVVTILLGS-SGMMLPSLTSSVYFFVFLGLCTWWSWCRTFDPLLFSCLCVL
LAIFTAGHLIGLYLYQFQFFQEAVPPSDYYA-RLFGIKSVIQTDCSSTWKIIVNPDLSWY
HHANPILLLVMYYTLATLI-RIWLQEPL--VQEERTK------EEDKALACSPIQI-TAE
RRRSLWYATHYPTDERK-------------GLLVTVNGNPVDYHTIHPSLPMENGPGKAD
LYSTPQYRWEPSDDSSEKQEE-EEEEKEEFEEERSREEKRSIKVHAMVSVFQFIMKQSYI
CALIAMM-AWSITYHSWLTFVLLIWSCTLWMIRNRRKYAMISSPFMVVYGNLLLILQYIW
SFELP--EIKKVPGFLEKKEPGELAS---------KILFTITFWLLLRQHLTEQKALREK
EALLSEVKIGSQENEEK----GKLVYM---------------------------------
---------VCGQRKQERKKVEEEE---VEEEDEQDIMKVLGNLVVAMFIKYWIYVCGGM
FFFVSFEGKIVMYKIIYMVLFLFCVALYQVHYEWWRKILKYFWMSVVIYTMLVLIFIYTY
QFENFPGLWQNMTGLKKENLLSLSPTCLLVASLCFR------------------------
------L------PPRSHAKVNGRVYLII----NRWLLSTNRLAHPEGSLPDLTMMHLTA
NLEKPEVRKLAEPGEEKPEGYSEKAQ--KGDLGKDSEESEEDGE-EE-----EESEE-EE
ETPDLRNKWHLVIDRLTVLFLKFLEYFHKLQVFMWWILELHIIKIVSSYIIWVSVKE--V
SLFNYVFLISWAFALPYAKLRRLASSVCTVWTCVIIVCKMLYQLQTIKPENFSVNCSLPN
ENQTNIP-LNELNKSLLYSAP-IDPTEWVGLRKSSPLLVYLRNNLLMLAILAFEVTIYRH
QEYYRGRNNLTAPVSKTIFHDITRLHLDDGLINCAKYFINYFFYKFGLETCFLMSVNVIG
QRMDFYAMIHACWLIAVLYRRRRKAIAEIWPKYCCFLACIITFQYFICIGIPPAPCRDYP
WRFKGASFNDNIIKWLYFPDFIVRPNPVFLVYDFMLLLCASLQRQIFEDENKAAVRIMAG
DNVEICMNLDAASFSQHNPVPDFIHC-RSYLDMSKVIVFSYLFWFVLTIIFITGTTRISI
FCMGYLVACFYFLLFGGDLLLKPIKSILRYWDWLIAYNVFVITMKNILSVSGSHCITH-K
QS

PF15917 // ENSGT00390000013029_1_Domain_0 (1503, 1775)

ARWLLKAQCLSCYAANSEF-------ETAANSPCTLPSGEAGIIWDSICFAFLLLQRR
VFMSYYFLHVVA--------DIKASQILASRGAELFQATIVKAVKARIEEEKKSMDQLKR
QMDRIKARQQKYKKGKERMLSLTQEPGEGQDIQKLSEEDDE-READKQKAKGKKKQWWRP
WVDHASMVRSGDYYLFETDSEEEEEEELKKEDEEPPRRSAF-------------------
--------------QFVYQAWITDPKTALRQRHK

ENSGT00390000013029_1_Linker_0_3 (1775, 2665)

EKKRSAREERKRRRKGSKEGP--VEW
EDREDEPIKKKSDGPDNIIKRIFNILKFTWVLFLATVDSFTTWLNSISREHIDISTVLRI
ERCMLTREIKKGN-VPTRESI-HMYYQNHI-MNLSRESGLDTIDERPGAASGAQTAHRMD
SLD---SHDSIS------------------------------------------------
--------SEPTQCTMLYSRQGTTETIEEVEAEQEEEAGSTVSEPREAKEYE--------
-------AAGYDAGAMGAEEASLTPE---EELTQFSTLDGDVEAPPSYSKAVSFEHLSFG
SQDD-SAGKNHMAVSPDDSRTD-----KLGSSILPPLTHELTASELLLNKMFHDDE--LE
ESEKFYVGQPRFLLLFYAMYNTLVARSEMVCYFVIILNHMVSASMITLLLPILIFLWAML
SVPRPSRRFWMMAIVYTEVAIVVKYFFQFGFFPWNKNAEV--NKDKPYHPPNIIGVEKKE
GYVLYDLIQLLALFFHRS--ILKCHGLWDEDDMTESGTDKGESDDEL---SLGHGRRGSS
---DSLKSINLAASVES-----------------VHVTFPEQQTAVRRKR--SSSNSEPS
QRSSFSSNRSQR-----GST-STRNSSQKG--SSVLSIK-----QKSKRELY-MEKLQEH
LIKAKAF----------------TIKKTLQIYVPIKQFFYNLIHPDYSAVTDVYVLMFLA
DTVDFIIIVFGFWAFGK-HSAAADITSSLSEDQVPGPFLVMVLIQFGTMVVDRALYLRKT
VLGKVIFQVILVFGIHFWMFFILPGVTERKFSQNLVAQLWYFVKCVYFGLSAYQIRCGYP
TRVLGNFLTKSYNYVNLFLFQGFR

PF12166 // ENSGT00390000013029_1_Domain_3 (2665, 3094)

LVPFLTELRAVMDWVWTDTTLSLSSWICVEDIYAHI
FILKCWRESEKRYPQPRGQKKKKVVKYGMGGMIIVLLICIVWFPLLFMSLIKSVAGVINQ
PLDVSVTITLGGYQPIFTMSAQQSQLKVMDQQNFNKFIQA-----FSRDTGAMQFLENYE
KEDITVAELEGNSNSLWTISPPSKQKMIHELLDPNSSFSVVFSWSIQRNLSLGAKSEIAT
DKLSFPLKNMTRKNIAKMIAGNSTEGSKTPVTIEKIYPYYVKAPSDSNSKPIKQLLS--E
NNFMDITI-------------ILSRDNTTKYNSEWWVLNLTGNRIYNPNSQALELVVFND
KVSPPSLGFLAGYGIMGLYASVVLVIGKFVREFFSGISHSIMFEELPNVDRILKLCTDIF
LVRETGELELEEDLYAKLIFLYRSPETMIKWTREKTN

----------MASEVVCGLIFRLLLPICLAVACAFRYNGLSFVYLIYLLLIPLFSEPTKT
T------MQGHTGRLLKSLCFISLSFLLLHIIFHIT-----LASLEAQHRIAPGYNCSTW
EK---TFRQIGFESLKGADAGNGIRVFVPDIGMFVASLTIWLLCRNIVQKPVTDEAAQSN
LEFENEELAGGEKIDSEEALIYE-EDLDGGDGVEGELEESTRLKMFRRLACVASKLKEFI
GNMITTAGKVVVTILLGS-SGMMLPSLTSSVYFFVFLGLCTWWSWCRTFDPLLFSCLCVL
LAIFTAGHLIGLYLYQFQFFQEAVPPSDYYA-RLFGIKSVIQTDCSSTWKIIVNPDLSWY
HHANPILLLVMYYTLATLI-RIWLQEPL--VQEERTK------EEDKALACSPIQI-TAE
RRRSLWYATHYPTDERKLLSMTQDDYKPSDGLLVTVNGNPVDYHTIHPSLPMENGPGKAD
LYSTPQYRWEPSDESSEKREE-EEEEKEEFEEERSHEEKRSIKVHAMVSVFQFIMKQSYI
CALIAMM-AWSITYHSWLTFVLLIWSCTLWMIRNRRKYAMISSPFMVVYGNLLLILQYIW
SFELP--EIKKVPGFLEKKEPGELAS---------KILFTITFWLLLRQHLTEQKALREK
EALLSEVKIGSQENEEK-----DEELQDIQV---EGEPKEK-------------------
-----EEEEEAKEEKQERKKVEEEE---VEEEDEQDIMKVLGNLVVAMFIKYWIYVCGGM
FFFVSFEGKIVMYKIIYMVLFLFCVALYQVHYEWWRKILKYFWMSVVIYTMLVLIFIYTY
QFENFPGLWQNMTGLKKEKLEDLGLKQFTVAELFTRIFIPTSFLLVCILHLHYFHDRFLE
LTDLKSIPSKEDNTIYSHAKVNGRVYLIINSIKKKLPIHQNELAHPEGSLPDLTMMHLTA
KREKPEVRKLAEPGEEKPEGYSEKAQ--KGDLGKDSEESEEDGE-EE-----EESEE-EE
ETSDLRNKWHLVIDRLTVLFLKFLEYFHKLQVFMWWILELHIIKIVSSYIIWVSVKE--V
SLFNYVFLISWAFALPYAKLRRLASSVCTVWTCVIIVCKMLYQLQTIKPENFSVNCSLPN
ENQTNIP-LNELNKSLLYSAP-VDPTEWVGLRKSSPLLVYLRNNLLMLAILAFEVTIYRH
QEYYRGRNNLTAPVSKTIFHDITRLHLDDGLINCAKYFINYFFYKFGLETCFLMSVNVIG
QRMDFYAMIHACWLIAVLYRRRRKAIAEIWPKYCCFLACIITFQYFICIGIPPAPCRDYP
WRFKGASFNDNIIKWLYFPDFIVRPNPVFLVYDFMLLLCASLQRQIFEDENKAAVRIMAG
DNVEICMNLDAASFSQHNPVPDFIHC-RSYLDMSKVIVFSYLFWFVLTIIFITGTTRISI
FCMGYLVACFYFLLFGGDLLLKPIKSILRYWDWLIAYNVFVITMKNILSIG

PF15917 // ENSGT00390000013029_1_Domain_0 (1492, 1775)

ACGYIGTLV
HNSCWLIQAFSLACTVKGYQ--------MPAANSPCTLPSGEAGIIWDSICFAFLLLQRR
VFMSYYFLHVVA--------DIKASQILASRGAELFQATIVKAVKARIEEEKKSMDQLKR
QMDRIKARQQKYKKGKERMLSLTQEPGEGQDMQKLSEEDDE-READKQKAKGKKKQWWRP
WVDHASMVRSGDYYLFETDSEEEEEEELKKEDEEPPRRSAF-------------------
--------------QFVYQAWITDPKTALRQRHK

ENSGT00390000013029_1_Linker_0_3 (1775, 2665)

EKKRSAREERKRRRKGSKEGP--VEW
EDREDEPIKKKSDGPDNIIKRIFNILKFTWVLFLATVDSFTTWLNSISREHIDISTVLRI
ERCMLTREIKKGN-VPTRESI-HMYYQNHI-MNLSRESGLDTIDERPGAASGAQTAHRMD
SLD---SHDSIS------------------------------------------------
--------SEPTQCTMLYSRQGTTETIEEVEAEQEEEAGSTVPEPREAKEYE--------
-------ATGYDVGAMGAEEASLTPE---EELTQFSTLDGDVEAPPSYSKAVSFEHLSFG
SQDD-SAGKNHMAVSPDDSRTD-----KLGSSILPPLTHELTASELLLNKMFHDDE--LE
ESEKFYVGQPRFLLLFYAMYNTLVARSEMVCYFVIILNHMVSASMITLLLPILIFLWAML
SVPRPSRRFWMMAIVYTEVAIVVKYFFQFGFFPWNKNAEV--NKDKPFHPPNIIGVEKKE
GYVLYDLIQLLALFFHRS--ILKCHGLWDEDDMTESGMDKEESDDEL---SLGHGRRDSS
---DSLKSINLAASVES-----------------VHVTFPEQQTAVRRKR--SSSNSEPS
QRSSFSSNRSQR-----GST-STRNSSQKG--SSVLSIK-----QKSKRELY-MEKLQEH
LIKAKAF----------------TIKKTLQIYVPIKQFFYNLIHPDYSAVTDVYVLMFLA
DTVDFIIIVFGFWAFGK-HSAAADITSSLSEDQVPGPFLVMVLIQFGTMVVDRALYLRKT
VLGKVIFQVILVFGIHFWMFFILPGVTERKFSQNLVAQLWYFVKCVYFGLSAYQIRCGYP
TRVLGNFLTKSYNYVNLFLFQGFR

PF12166 // ENSGT00390000013029_1_Domain_3 (2665, 3094)

LVPFLTELRAVMDWVWTDTTLSLSSWICVEDIYAHI
FILKCWRESEKRYPQPRGQKKKKVVKYGMGGMIIVLLICIVWFPLLFMSLIKSVAGVINQ
PLDVSVTITLGGYQPIFTMSAQQSQLKVMDQQNFNKFIQA-----FSRDTGAMQFLENYE
KEDITVAELEGNSNSLWTISPPSKQKMIHELLDPNSSFSVVFSWSIQRNLSLGAKSEIAT
DKLSFPLKNITRKNIAKMIAGNSTESSKTPVTIEKIYPYYVKAPSDSNSKPIKQLLS--E
NNFMDITI-------------ILSRDNTTKFNSEWWVLNLTGNRIYNPNSQALELVVFND
KVSPPSLGFLAGYGIMGLYASVVLVIGKFVREFFSGISHSIMFEELPNVDRILKLCTDIF
LVRETGELELEEDLYAKLIFLYRSPETMIKWTREKTN

------------------------------------------------------------
---------------LKSLCFTSLSFLLLHIIFHIT-----LASLEAQHRIAPGYNCSTW
EKTFRQIGFE---SLKGADAGNGIRVFVPDIGMFIASLTIWLVCRSMVQKPALEETAQDT
PEFENEELARGEKMDSKEALIDD-EDLDGGDGEDGEPEDSTRLKLLRQLASVASRLKEFV
GNMITTAGKVVVTILLGS-SGMMLPSLTSAVYFFVFLGLCTWWSWCRTFDPLLFSCLCVL
LAIFTAGHLIGLYLYQFQFFQEAVPPNDYYA-RLFGIKSVIQTDCSSTWKIVVNPDLSWY
HHANPILLLVMYYTLATLI-RIWLQEPL--VRDRGACG------L----GSS-------Q
RRCSV---CSQSPVLPKLLSMTQDDYKPSDGLLVTVNGNPVDYHTIHPSLPLENGPAKAD
LYSTPRYRWEPSEESTEKKED-EEGEKEESEEERSQEDRRSVRVHAMVSVFHFIMKQSYI
CALIAMM-AWSITYHSWLTFVLLIWSCTLWMIRNRRKYAMISSPFMVVYANLLLVLQYIW
SFELP--EIKKVPGFLEKKDPGELAS---------KILFTITFWLLLRQHLTEQKALREK
EALLSEVKIGSQEHEEK-----DEELQDVQVE---GEPTEKEEEEGVKEEKQE-------
-------------------KRKEEE-EAEEDEDDQDIMKVLGNLVVAMFIKYWIYVCGGM
FFFVSFEGKIVMYKIIYMVLFLFCVALYQVHYEWWRKILKYFWMSVVIYTMLVLIFIYTY
QFENFPGLWQNMTGLKKEKLEDLGLKQFTVAELFTRIFIPTSFLLVCILHLHYFHDRFLE
LTDLKSIPSKEDSAIYSHAKVNGRVYLIIN-----------RLAHPEGSLPDLAMMHLTP
SLDKPEPKKLVEPEQEKLEGQGQMERAGKGEP--GKDGKDEDEEDEE-----ESEEEEEE
DMSDLRNKWHLVIDRLTVLFLRFLEYFHKLQVFMWWILELHIIKVVSSYIIWVSVKE--V
SLFNYVFLISWAFALPYARLRRLASSVCTVWTCVIIVCKMLYQLQTIKPSTFSINCTLPN
ENQTNIP-LNELNKSLLYSAP-IDPTEWVGLRKSSPLLVYLRNNLLMLAILAFEVTIYRH
QEYYRGRNNLTAPVSRTIFHDITRLHLDDGLVNCAKYFVNYFFYKFGLETCFLMSVNVIG
QRMDFYAMIHACWLIGVLYRRRRKAIAEVWPKYCCFLACILTLQYLVCIGVPPAPCRDYP
WRLRGADFNNNIIKWLYFPDFIVRPNPVFLVYDFMLLLCASLQRQIFEDENKAAVRIMAG
DNVEICMNLDAASFSQHNPVPDFIHC-RSYLDMSKVVIFSYLFWFVLTIIFITGTTRISI
FCMGYLVACFYFLLFGGDLLLKPIRSILRYWDWLIAYNVFVITMKNILSIG

PF15917 // ENSGT00390000013029_1_Domain_0 (1492, 1775)

ACGYIGTLV
KNSCWLIQAFSLACTVKGYKM--------PSDDTSCKLPSGEAGIIWDSICFAFLLLQRR
VFMSYYFLHVVA--------DIKASQILASRGAELFQATIVKAVKARIEEEKKSMDQLKR
QMDRIKARQQKYKKGKERMLSLTQESGEGQDTQKVSEEDDE-READKQKAKGKKKQWWRP
WVDHASMVRSGDYYLFETDSEEEEEEELKKEDEEPPKKSAF-------------------
--------------QFVYQAWITDPKTALRQRRK

ENSGT00390000013029_1_Linker_0_3 (1775, 2665)

EKKKSAREEQKRRRRGSGEGP--VEW
EDREEEPVKKKSDGPDNIIKRIFNIVKFTWVLFLATVDSFTTWLNSISREHIDISTVLRI
ERCMLTREIKKGN-VPTRESI-HMYYQNHI-MNLSRESGLDTIEDRPGAGARAPPAHRMD
SLD---SHDSISSCYTEATTLFSRQSTLDDLDGPDPVPKTSERSRPRLRKMLSMDMSSSS
ADSGSLVSSEPTQCTTLYSRQGTTETIEEVEAEVEEEAVGAQKEETEEDQEE--------
-----EEEEYRLGYG-----AEA--EEDEDELPQVSTDDGDVEAPPSYSKAVSFEHLSFG
-SQDGAGAKNHMVVSPDDSRTDK-----LESSLLPPLTHELTASELLLNKMFHDDE--LE
ESEQFYVGQPRFLLLFYAMYNTLVARSEMVCYFVIILNHMVSASMITLLLPILIFLWAML
SVPRPSRRFWMMAIVYTEVAIVVKYFFQFGFFPWNKNVEI--HKDKPYHPPNIIGVEKKE
GYVLYDLIQLLALFFHRS--ILKCHGLWDEDDVVDSSTDKEDSDAEP---SLSHSRRGSA
---DSLKSINLAASVES-----------------VHVTFPEPPAAMRRK--RSSCSSPDS
PGSSFSSNRSKR-----GST-STRNSSQKG--GSVLSEK-----KESRRELY-MKKLQE-
--------------H-LVQAKDFTIRKTLQIYVPIRQFFYNLIHPDYSAVTDVYVLMFLA
DTVDFVIIVFGFWAFGK-HSAAADITSSLSEDQVPGPFLVMVLIQFGTMVVDRALYLRKT
VLGKVIFQVILVFGIHFWMFFILPGVTERKFSQNLVAQLWYFVKCVYFGLSAYQIRCGYP
TRVLGNFLTKSYNYVNLFLFQGFR

PF12166 // ENSGT00390000013029_1_Domain_3 (2665, 3094)

LVPFLTELRAVMDWVWTDTTLSLSSWICVEDIYAHI
FILKCWRESEKRYPQPRGQKKKKVVKYGMGGMIIVLLICIVWFPLLFMSLIKSVAGVINQ
PLDVSVTITLGGYQPIFTMSAQQSQLKVMDPQRYNKFWRM-----FSRDTGAMQFLENYE
REDITVAELEGNSNSLWTISPPSKQKMIQELTDPNSSFSVVFSWSIQRNMSLGAKAEIAT
DKLSFLLEDVTRESIAKMIAGNDTESSKTPVTIEKIYPYYVKAPSDSNSKPIKQLLS--E
KDFMNITI-------------ILSRDNVTKSNSEWWVLNLTGNRIYDRESQALELVVFND
KVSPPSLGFLAGYGIMGLYASVVLVIGKFVREFFSGISHSIMFEELPNVDRILKLCTDIF
LVRETGELELEEDLYAKLIFLYRSPETMIKWTREKTN

------------------------------------------------------------
---------------LKSLCFTSLSFLLLHIIFHIT-----LASLEAQHRIAPSYNCSTW
EKTFRQIGFE---SLKGADAGNGIRVFVPDIGMFIASLTIWLVCRNMVQKPAQEETVQDS
LEFESEELARGEKVDSKEALIDEDKDLDGGDGEDVELEDSARLKLFRQLASVASRLKEFV
GNMITTAGKVVVTILLGS-SGMMLPSLTSAVYFLVFLGLCTWWSWCRTFDPLLFSCLCVL
LAIFTAGHLIGLYLYQFQFFQEAVPPNDYYA-RLFGIKSVIQTDCSNTWKIIVNPDLSWY
HHANPILLLVMYYTLATLI-RIWLQEPL--VPDEPAKE------EDHALGDSPKQHYSAE
RRRSLWYAAHYPTDERKLLSMTQDDYKPSDGLLVTVNGNPVDYHTIHPSLPLENGPAKPD
LYSTPCYRWEPSEESAEKKED-EEGEKEEFEEERSQDDRRSVRVHAMVSVFHFIMKQSYI
CALIAMM-AWSITYHSWLTFVLLIWSCTLWMIRNRRKYAMISSPFMVVYANLLLVLQYIW
SFELP--EIKKVPGFLEKKEPGELAS---------KILFTITFWLLLRQHLTEQKALREK
EALLAEVKIGSQEHEEK-----DEELQDVQVE---GEPREKKEEEGAKEEKPE-------
-------------------RRKEEE-EAEEEEDDQDIMKVLGNLVVAMFIKYWIYVCGGM
FFFVSFEGKIVMYKIIYMVLFLFCVALYQVHYEWWRKILKYFWMSVVIYTMLVLIFIYTY
QFENFPGLWQNMTGLKKEKLEDLGLKQFTVAELFTRIFIPTSFLLVCILHLHYFHDH---
---LKSIPSKEDSAIYSHAKVNGRVYLIIN-----------RLAHPEGSLPDLAMMHLTP
SLDKPEPKKLAEPGQEKPEGRGKTERALKGES--ETDSQDEDEE----------ESEEEE
DMSDLRNKWHLVIDRLTVLFLKFLEYFHKLQVFMWWLLELHIIKVVSSYIIWVSVKE--V
SLFNYVFLISWAFALPYAKLRRLASSVCTVWTCVIIVCKMLYQLQTIKPSNFSINCSLPN
ESQTNIP-LSELNKSLLYSAP-IDPTEWVGLRKSSPLLVYLRNNLLMLAILAFEVTIYRH
QEYYRGRNNLTAPVSKTIFHDITRLHLDDGLVNCAKYFVNYFFYKFGLETCFLMSVNVIG
QRMDFYAMIHACWLIGVLYRRRRKAIAEVWPKYCCFLACILTLQYLVCIGVPPAPCRDYP
WRLKGANFNDNIIKWLYFPDFIMRPNPVFLVYDFMLLLCASLQRQIFEDENKAAVRIMAG
DNVEICMNLDAASFSQHNPVPDFIHC-RSYLDMSKVVIFSYLFWFVLTIIFITGTTRISI
FCMGYLVACFYFLLFGGDLLLKPIRSILRYWDWLIAYNIFVITMKNILSIG

PF15917 // ENSGT00390000013029_1_Domain_0 (1492, 1775)

ACGYIGTLV
KNSCWLIQAFSLACTVKGYKM--------PSDDSNCRLPSGEAGIIWDSICFAFLLLQRR
VFMSYYFLHVVA--------DIKASQILASRGAELFQATIVKAVKARIEEEKKSMDQLKR
QMDRIKARQQKYKKGKERMLSLTQESGEGQDAQKLSEEDDE-READKQKAKGKKKQWWRP
WVDHASMVRSGDYYLFETDSEEEEEEELKKEDEEPPRKSAF-------------------
--------------QFVYQAWITDPKTALRQRRK

ENSGT00390000013029_1_Linker_0_3 (1775, 2665)

EKKKSAREEQKRKRRGSGQGP--VEW
EDREEEPVKKKSDGPDNIIKRIFNIVKFTWVLFLATVDSFTTWLNSISREHIDISTVLRI
ERCMLTREIKKGN-VPTRESI-HMYYQNHI-MNLSRESGLDTIEEGPRAGPRAPAAHRMD
SLD---SHDSISSCYTEATMLFSRQSTLDDLDGPDPVPKTSERSRPRLRKMLSMDMSSSS
ADSGSLVSSEPTQCTMLYSRQGTTETIEEVEAEVEEEAVEEEE-------KE--------
-----EYGVGY-----G----VE--EDDDDELPQVSTDDGEVEAPPSYSKAVTCEHLSFG
-SQDGIGAKNQMVVSPDDSR-----TDKLGSSLLPPLTHELTASELLLNKMFHDDE--LE
ESERFYVGQPRFLLLFYAMYNTLVARSEMVCYFVIILNHMVSASMITLLLPILIFLWAML
SVPRPSRRFWMMAIVYTEVAIVVKYFFQFGFFPWNKNVEV--HKDKPYHPPNIIGVEKKE
GYVLYDLIQLLALFFHRS--ILKCHGLWDEDDVVDSGTDKEDSDAEL---SLGHSRRDSA
---DSLKSINLAASVES-----------------VHVTFPEPPTAVRRK--RSSCSSPVS
PGSSFSSNRSKR-----GST-STRNSSQKG--SSILGVK-----QRSRRELY-VKKLQE-
--------------H-LVQAKNFTIRKTLQIYVPIRQFFYNLIHPDYSAVTDVYVLMFLA
DTVDFVIIVFGFWAFGK-HSAAADITSSLSEDQVPGPFLVMVLIQFGTMVVDRALYLRKT
VLGKVIFQVILVFGIHFWMFFILPVVTERKFSQNLVAQLWYFVKCVYFGLSAYQIRCGYP
TRVLGNFLTKSYNYVNLFLFQGFR

PF12166 // ENSGT00390000013029_1_Domain_3 (2665, 3094)

LVPFLTELRAVMDWVWTDTTLSLSSWICVEDIYAHI
FILKCWRESEKRYPQPRGQKKKKVVKYGMGGMIIVLLICIVWFPLLFMSLIKSVAGVINQ
PLDVSVTITLGGYQPIFTMSAQQSQLKVMDQQRFNKFLKD-----FSRDTGAMQFLENYE
REDITVAELEGNSNSLWTISPPSKQKMIQELKDPNSSFSVVFSWSIQRNMSLGAKAEIAT
DKLTFPLKNVTREQIAKMIAGNDTESSKMPVTIEKLYPYYVKAPSDSNSKPIKQLLS--E
KDFMNITI-------------ILSRDNMTKSNSEWWVLNLTGNRIYDREAQALELVVFND
KVSPPSLGFLAGYGIMGLYASVVLVIGKFVREFFSGISHSIMFEELPNVDRILKLCTDIF
LVRETGELELEEDLYAKLIFLYRSPETMIKWTREKTN

----------MASEVVCGLIFRLLLPICLAVACAFRYNGLSFVYLIYLLLIPLFSEPTKA
T------MQGHTGRLLQSLCITSLSFLLLHIIFHIT-----LASLEAQHRIAPAYNCSTW
EKTFRQIGFE---SLKGADAGNGIRVFVPDIGMFIASLTIWLVCRTIVKKPDTEEIAQLN
SECENEELAGGEKMDSEEALIYE-EDLDGEEGMEGELEESTKLKILRRFASVASKLKEFI
GNMITTAGKVVVTILLGS-SGMMLPSLTSAVYFFVFLGLCTWWSWCRTFDPLLFGCLCVL
LAIFTAGHLIGLYLYQFQFFQEAVPPNDYYA-RLFGIKSVIQTDCASTWKIIVNPDLSWY
HHANPILLLVMYYTLATLI-RIWLQEPL--VQEEMAK------EDEGALDCSSNQN-TAE
RRRSLWYATHYPTDERKLLSMTQDDYKPSDGLLVTVNGNPVDYHTIHPSLPIENGPAKTD
LYTIPQYRWEPSEESSEKKEE-EEDKREDSEGEGSQEEKRSVRMHAMVAVFQFIMKQSYI
CALIAMM-AWSITYHSWLTFVLLIWSCTLWMIRNRRKYAMISSPFMVVYANLLLVLQYIW
SFELP--EIKKVPGFLEKKEPGELAS---------KILFTITFWLLLRQHLTEQKALREK
EALLSEVKIGSQELEEK----EDEELQDVQV---EGEPTE--------------------
--KEEEEEEEIKE---ERHEVKKEEEEEVEEDDDQDIMKVLGNLVVALFIKYWIYVCGGM
FFFVSFEGKIVMYKIIYMVLFLFCVALYQVHYEWWRKILKYFWMSVVIYTMLVLIFIYTY
QFENFPGLWQNMTGLKKEKLEDLGLKQFTVAELFTRIFIPTSFLLVCILHLHYFHDRFLE
LTDLKSIPSKEDNTIYSHAKVNGRVYLIIN-----------RLAHPEGSLPDLAIMNMTA
SLDKPEVQKLAESGEERPEECVKKTE--KGEAGKDSDESEEEED-EE-------EESEEE
ESSDLRNKWHLVIDRLTVLFLKFLEYFHKLQVFMWWILELHIIKIVSSYIIWVTVKE--V
SLFNYVFLISWAFALPYAKLRRAASSVCTVWTCVIIVCKMLYQLQTIKPENFSVNCSLPN
ENQTNIP-LHELNKSLLYSAP-VDPTEWVGLRKSSPLLVYLRNNLLMLAILAFEVTVYRH
QEYYRGRNNLTAPVSKTIFHDITRLHLDDGLINCAKYFVNYFFYKFGLETCFLMSVNVIG
QRMDFYAMIHACWLIGVLYRRRRKAIAEVWPKYCCFLACIITFQYFVCIGIPPAPCRDYP
WRFKGAYFNDNIIKWLYFPDFIVRPNPVFLVYDFMLLLCASLQRQIFEDENKAAVRIMAG
DNVEICMNLDAASFSQHNPVPDFIHC-RSYLDMSKVIIFSYLFWFVLTIIFITGTTRISI
FCMGYLVACFYFLLFGGDLLLKPIKSILRYWDWLIAYNVFVITMKNILSIG

PF15917 // ENSGT00390000013029_1_Domain_0 (1492, 1774)

ACGYIGALV
RNSCWLIQAFSLACTVKGYQ--------MPEDDSRCKLPSGEAGIIWDSICFAFLLLQRR
VFMSYYFLHVVA--------DIKASQILASRGAELFQATIVKAVKARIEEEKKSMDQLKR
QMDRIKARQQKYKKGKERMLSLTQESGEGQDIQKVSEEDDE-READKQKAKGKKKQWWRP
WVDHASMVRSGDYYLFETDSEEEEEEELKKEDEEPPRKSAF-------------------
--------------QFVYQAWITDPKTALRQRR

ENSGT00390000013029_1_Linker_0_3 (1774, 2665)

KEKKKLAREEQKERRKGSGDGP--VEW
EDREDEPVKKKSDGPDNIIKRIFNILKFTWVLFLATVDSFTTWLNSISREHIDISTVLRI
ERCMLTREIKKGN-VPTRESI-HMYYQNHI-MNLSRESGLDTIDEHSGAGSRAQAAHRMD
SLD---SRDSISSCYTEATLLISRQSTLDDLDGQDPVPKTSERARPRLRKMFSLDMSSSS
ADSGSVASSEPTQCTMLYSRQGTTETIEEVEAEADEEVVEGLEPELHDAEEK--------
-----EYAAE---YEAGVEEVSLTPD---EELPQFSTDDGDVEAPPSYSKAVSFEHLSFA
SQDD-SGAKNHMVVSPDDSRTD-----KLESSILPPLTHELTASDLLMSKMFHDDE--LE
ESEKFYVDQPRFLLLFYAMYNTLVARSEMVCYFVIILNHMTSASIITLLLPILIFLWAML
SVPRPSRRFWMMAIVYTEVAIVVKYFFQFGFFPWNKDLEI--YKERPYFPPNIIGVEKKE
GYVLYDLIQLLALFFHRS--ILKCHGLWDEDDIVDSNTDKEGSDDEL---SLDQGRRGSS
---DSLKSINLAASVES-----------------VHVTFPEQPAAIRRKR--SCSSSQIS
PRSSFSSNRSKR-----GST-STRNSSQKG--SSVLSLK-----QKSKRELY-MEKLQEH
LIKAKAF----------------TIKKTLQIYVPIRQFFYDLIHPDYSAVTDVYVLMFLA
DTVDFIIIVFGFWAFGK-HSAAADITSSLSEDQVPGPFLVMVLIQFGTMVVDRALYLRKT
VLGKVIFQVILVFGIHFWMFFILPGVTERKFSQNLVAQLWYFVKCVYFGLSAYQIRCGYP
TRVLGNFLTKSYNYVNLFLFQGFR

PF12166 // ENSGT00390000013029_1_Domain_3 (2665, 3094)

LVPFLTELRAVMDWVWTDTTLSLSSWICVEDIYAHI
FILKCWRESEKRYPQPRGQKKKKAVKYGMGGMIIVLLICIVWFPLLFMSLIKSVAGVINQ
PLDVSVTITLGGYQPIFTMSAQQSQLKVMDNSKYNEFLKS-----FGPNSGAMQFLENYE
REDITVAELEGNSNSLWTISPPSKQKMIQELTDPNSCFSVVFSWSIQRNMTLGAKAEIAT
DKLSFPLADATRNSIAKMIAGNDTESSNTPVTIEKIYPYYVKAPSDSNSKPIKQLLS--E
NNFMNITI-------------ILFRDNVTKSNSEWWVLNLTGSRIFNQGSQALELVVFND
KVSPPSLGFLAGYGIMGLYASVVLVIGKFVREFFSGISHSIMFEELPNVDRILKLCTDIF
LVRETGELELEEDLYAKLIFLYRSPETMIKWTREKTN

----------MASEVVCGLVFRLLLPICLAVACAFRYNGLSFVYLIYLLLIPLFSEPTKA
T------MQGHTGRLLQSLCITSLSFLLLHIIFHIT-----LASLEAQHRIAPAYNCSTW
EKTFRQIGFE---SLKGADAGNGIRVFVPDVGMFIASLTIWLVCRNIVKKPDTEEVAQFN
PDCENEELAGGEKMDSEEALIYE-EDLDGEEGMEGELEESTKLKMFRRLASVASKLKEFI
GNMITTAGKVVVTILLGS-SGMMLPSLTSAVYFFVFLGLCTWWSWCRTFDPLLFGCLCVL
LAIFTAGHLIGLYLYQFQFFQEAVPPNDYYA-RLFGIKSIIQTDCSSTWKIIVNPQLSWY
HHANPILLLVMYYTLATLI-RIWLQEPL--VQDEMAK------EDEGTLDCSSNQN-TAE
RRRSLWYATQYPTDERKLLSMTQDDYKPSDGLLVTVNGNPVDYHTIHPSLPLENGPAKTD
LYTTPQYRWEPSEESSEKKEE-DEDKKEGSEGEGSQEEKRSVRIHAMVTVFQFIMKQSYI
CALIAMM-AWSITYHSWLTFVLLIWSCTLWMIRNRRKYAMISSPFMVVYANLLLVLQYIW
SFELT--EIKKVPGFLEKKNPGELAS---------KILFTITFWLLLRQHLTEQKALREK
EALLSEVKIGSQELEE----REDEELQDIQV---E-----------------------GE
PPEKAE-EEEIKE---ERHELKKEEEEEVEEDDDQDIMKVLGNLVVALFIKYWIYVCGGM
FFFVSFEGKIVMYKIIYMVLFLFCVALYQVHYEWWRKILKYFWMSVVIYTMLVLIFIYTY
QFENFPGLWQNMTGLKKEKLEDLGLKQFTVAELFTRIFIPTSFLLVCILHLHYFHDRFLE
LTDLKSIPSKEDNTIYSHAKVNGRVYLIIN-----------RLAHPEGSLPDLAVMNMTT
SLDKPEVQKLVEAGEERPEECAKKAE--KGQPGKDSDESEEEED-EE-------EESEEE
ETSDLRNKWLLVIDRLTVLFLKFLEYFHKLQVFMWWILELHIIKIVSSYIIWVTVKE--V
SLFNYVFLISWAFALPYAKLRRVASSVCTVWTCVIIVCKMLYQLQTIKPENFSVNCSLPN
ENQTNIP-LNELNKSLLYSAP-VDPTEWVGLRKSSPLLVYLRNNLLMLAILAFEVTIYRH
QEYYRGRNNLTAPVSKTIFHDITRLHLDDGLVNCAKYFINYFFYKFGLETCFLMSVNVIG
QRMDFYAMIHACWLIGVLYRRRRKAIAEVWPKYCCFLACIITFQYFVCIGIPPAPCRDYP
WRFKGANFNDNIIKWLYFPDFIVRPNPVFLVYDFMLLLCASLQRQIFEDENKAAVRIMAG
DNVEICMNLDAASFSQHNPVPDFIHC-RSYLDMSKVIIFSYLFWFVLTIIFITGTTRISI
FCMGYLVACFYFLLFGGDLLLKPIKSILRYWDWLIAYNVFVITMKNILSIG

PF15917 // ENSGT00390000013029_1_Domain_0 (1492, 1775)

ACGYISALV
RNSCWLIQAFSLACTVKGYK--------MPEDDSKCKLPSGEAGIIWDSICFAFLLLQRR
VFMSYYFLHVVA--------DIKASQILASRGAELFQATIVKAVKARIEEEKKSMDQLKR
QMDRIKARQQKYKKGKERMLSLTQESGEGQDIQKLSEEDDE-READKQKAKGKKKQWWRP
WVDHASMVRSGDYYLFETDSEEEEEEELKKEDEEPPRKSAF-------------------
--------------QFVYQAWITDPKTALRQRRK

ENSGT00390000013029_1_Linker_0_3 (1775, 2665)

EKKKLAREEEKGRRKGSGEGP--VEW
DDREDGPVKKKSDGPDNIIKRIFNILKFTWVLFLATVDSFTTWLNSISREHIDISTVLRI
ERCMLTREIKKGN-VPTRESI-HVYYQNHI-MNLSRESGLDTIDEHPGAGSRAQAAHRMD
SLD---SHDSISSCYTEATLLISRQSTLDDLDGQDPVPKTSERARPRLRKMFSMDMSSSS
ADSGSVASSEPTQCTMLYSRQGTTETIEEVEAEAEEEVVEGLESELHDEEDK--------
-----EYAAE---YEAGVEEVSLTPD---EELPQFSTDDGDVEAPPSYSKAVSFEHLSFA
SQDD-SGAKNHMVVSPDDSRTD-----KLESSILPPLTHELTASELLMNKMFHDDE--LE
ESEKFYVDQPRFLLLFYAMYNTLVARSEMVCYFVIILNHMISASIITLLLPILIFLWAML
SVPRPSRRFWMMAIVYTEVAIVVKYFFQFGFFPWNKDLEF--NKDKPYFPPNIIGVEKKE
GYVLYDLIQLLALFFHRS--ILKCHGLWDEDDIVDSGTDKEESDDEL---SLDHDRRGSS
---DSLKSINLAASVES-----------------VHVTFPEQPGPIRRKR--SCSSSQIS
PRSSFSSNRSKR-----GST-STRNSSQRG--SSVLSIK-----QKSKRELY-MEKLQEH
LIKAKAF----------------TIKKTLQIYIPIRQFFYDLIHPDYSAVTDVYVLMFLA
DTVDFIIIVFGFWAFGK-HSAAADITSSLSEDQVPGPFLVMVLIQFGTMVVDRALYLRKT
VLGKVIFQVILVFGIHFWMFFILPSVTERKFSQNLVAQLWYFVKCVYFGLSAYQIRCGYP
TRVLGNFLTKSYNYVNLFLFQGFR

PF12166 // ENSGT00390000013029_1_Domain_3 (2665, 3094)

LVPFLTELRAVMDWVWTDTTLSLSSWICVEDIYAHI
FILKCWRESEKRYPQPRGQKKKKAVKYGMGGMIIVLLICIVWFPLLFMSLIKSVAGVINQ
PLDVSVTITLGGYQPIFTMSAQQSQLKVMDNTKYKAFLKS-----FTTNSGAMQFLENYE
KEDITVAELEGNSNSLWTISPPSKQKMIQELTDPNSCFSVVFSWSIQRNMTLGAKAEIAT
DKLSFPLANETRNNIAKMIAGNDTESSNTPVTIEKIYPYYVKAPSDSNSKPIKQLLS--E
SNFMNITI-------------ILFRDNVTKSNSEWWVLNLTGNRIYNQGSQALELVVFND
KVSPPSLGFLAGYGIMGLYASVVLVIGKFVREFFSGISHSIMFEELPNVDRILKLCTDIF
LVRETGELELEEDLYAKLIFLYRSPETMIKWTREKTN

----------MASEVVCGLVFRLLLPICLAVACAFRYNGLSFVYLIYLLLIPLFSEPTKA
T------MQGHTGRLLQSLCLTSLSFLLLHIIFHIT-----LASLEAQHRLAPAYNCSTW
EKTFRQIGFE---SLKGADAGNGIRVFVPDVGMFIASLTIWLVCRNIVKKPDTEEVAQFN
SDCENEELAGAEKMDSEEALIYE-EELDGEEGMEGELEESTKLKMFRRLASVASKLKEFI
GNMITTAGKVVVTILLGS-SGMMLPSLTSAVYFFVFLGLCTWWSWCRTFDPLLFGCLCVL
LAIFTAGHLIGLYLYQFQFFQEAVPPNDYYA-RLFGIKSVIQTDCSSTWKIIVNPELSWY
HHANPILLLVMYYTLATLI-RIWLQEPL--VQDEMAK------EDEGTLDCPT-QN-TAE
RRRSLWYATQYPTDERKLLSMTQDDYKPSDGLLVTVNGNPVDYHTIHPSLPLENGPAKTD
LYTTPQYRWEPSEESSEKKEE-DEDKKEGSEGEGSQEEKRSVRIHAMVTVFQFIMKQSYI
CALIAMM-AWSITYHSWLTFVLLIWSCTLWMIRNRRKYAMISSPFMVVYANLLLVLQYIW
SFELP--EIKKVPGFLEKKEPGELAS---------KILFTITFWLLLRQHLTEQKALQEK
EALLSEVKIGSQELEE----RDDEELQDIQV---E-----------------------GE
APEKAEGEEEIKE---ERHELKKEEEEEVEEDDDQDIMKVLGNLVVALFTKYWIYVCGGM
FFFVSFEGKIVMYKIIYMVLFLFCVALYQVHYEWWRKILKYFWMSVVIYTMLVLIFIYTY
QFENFPGLWQNMTGLKKEKLEDLGLKQFTVAELFTRIFIPTSFLLVCILHLHYFHDRFLE
LTDLKSIPSKEDATIYSHAKVNGRVYLIIN-----------RLAHPEGSLPDLAIMNMTT
SLEKPEGQKVVEPGAERPEECAKKAE--KGEPGKDSDESEEEEE-EE-------EESEEE
ETSDLRNKWLLVIDRLTVLFLKFLEYFHKLQVFMWWILELHIIKIVSSYIIWVTVKE--V
SLLNYVFLISWAFALPYAKLRRVASSVCTVWTCVIIVCKMLYQLQTIKPENFSVNCSLPN
ENQTNIP-LNELNKSLLYSAP-VDPTEWVGLRKSSPLLVYLRNNLLMLAILAFEVTIYRH
QEYYRGRNKLTAPVSKTIFHDITRLHLDDGLINCAKYFINYFFYKFGLETCFLMSVNVIG
QRMDFYAMIHACWLIGVLYRRRRKAIAEVWPKYCCFLACIITFQYFVCIGIPPAPCRDYP
WRFKGAHFNDNIIKWLYFPDFIVRPNPVFLVYDFMLLLCASLQRQIFEDENKAAVRIMAG
DNVEICMNLDAASFSQHNPVPDFIHC-RSYLDMSKVIIFSYLFWFVLTIIFITGTTRISI
FCMGYLVACFYFLLFGGDLLLKPIKSILRYWDWLIAYNVFVITMKNILSIG

PF15917 // ENSGT00390000013029_1_Domain_0 (1492, 1774)

ACGYIGALV
RNSCWLIQAFSLACTVKGYK--------MPEDDSKCKLPSGEAGIIWDSICFAFLLLQRR
VFMSYYFLHVVA--------DIKASQILASRGAELFQATIVKAVKARIEEEKKSMDQLKR
QMDRIKARQQKYKKGKERMLSLTQESGEGQDIQKLSEEDDE-READKQKAKGKKKQWWRP
WVDHASMVRSGDYYLFETDSEEEEEEELKKEDEEPPRKSAF-------------------
--------------QFVYQAWITDPKTALRQRR

ENSGT00390000013029_1_Linker_0_3 (1774, 2665)

KEKKKLAREEEKGRRKGSGDGP--VEW
DDREGGPIKKKSDGPDNIIKRIFNILKFTWVLFLATVDSFTTWLNSISREHIDISTVLRI
ERCMLTREIKKGN-VPTRESI-HMYYQNHI-MNLSRESGLDTIDEHPGAGSRAQAAHRMD
SLD---SHDSISSCYTEATLLISRQSTLDDLDGQDPVPKTSERARPRLRKMFSMDMSSSS
ADSGSVGSSEPTQCTMLYSRQGTTETIEEVEAEAEEEVVEGLESELRDTEDK--------
-----EYVAE---YEAGVEEVSLTPD---EELPQFSTDDGDVEAPPSYSKAVSFEHLSFA
SQDD-SGAKNHMVVSPDDSRTD-----KLESSILPPLTHELTASELLMNKMFHDDE--LE
ESEKFYVDQPRFLLLFYAMYNTLVARSEMVCYFVIILNHMISASIITLLLPILIFLWAML
SVPRPSRRFWMMAIVYTEVAIVVKYFFQFGFFPWNKDLEL--NKDKPYFPPNIIGVEKKE
GYVLYDLIQLLALFFHRS--ILKCHGLWDEDDIVDSGTDKEESDDEL---SLDHGRRGSS
---DSLKSINLAASVES-----------------VHVTFPEQPGAVRRKR--SCSSTQIS
PQSSFSSNRSKR-----GST-STRNSSQRG--SSVLSIK-----QKSKRELY-MEKLQEH
FIKAKAF----------------TIKKTLQIYVPIRQFFYDLIHPDYSAVTDVYVLMFLA
DTVDFIIIVFGFWAFGK-HSAAADITSSLSEDQVPGPFLVMVLIQFGTMVVDRALYLRKT
VLGKVIFQVILVFGIHFWMFFILPSVTERKFSQNLVAQLWYFVKCVYFGLSAYQIRCGYP
TRVLGNFLTKSYNYVNLFLFQGFR

PF12166 // ENSGT00390000013029_1_Domain_3 (2665, 3094)

LVPFLTELRAVMDWVWTDTTLSLSSWICVEDIYAHI
FILKCWRESEKRYPQPRGQKKKKAVKYGMGGMIIVLLICIVWFPLLFMSLIKSVAGVINQ
PLDVSVTITLGGYQPIFTMSAQQSQLKVMDNAKYKTFLNS-----FTTNTGAMQFLENYE
KEDITVAELEGNSNSLWTISPPSKQKMIQELTDPNSFFSVVFSWSIQRNMTLGAKAEIAT
DKLSFPLANETRNNIAKMIAGNDTESSNTPVTIERIYPYYVKAPSDSNSKPIKQLLS--E
NNFMNITI-------------ILFRDNVTKSNSEWWVLNLTGNRIYNQGSQALELVVFND
KVSPPSLGFLAGYGIMGLYASVVLVIGKFVREFFSGISHSIMFEELPNVDRILKLCTDIF
LVRETGELELEEDLYAKLIFLYRSPETMIKWTREKTN

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------------------------------------------MARILT------------
----------------------CSCFHFPFRGAELFQATIVKAVKARIEEEKKSMDQLKR
QMDRIKARQQKYKKGKERMLSLTQEPGEGQDVQKLSEEDDE-READKQKAKGKKKQWWRP
WVDHASMVRSGDYYLFETDSEEEEEEELKKEDEEPPRRSAF-------------------
--------------QFVYQAWITDPKTALRQRHKEKKRSAREERKRRRKGSKEGP--VEW
EDREDEPIKKKSDGPDNIIKRIFNILKFTWVLFLATVDSFTTWLNSISREHIDISTVLRI
ERCMLTREIKKGN-VPTRESI-HMYYQNHI-MNLSRESGLDTIDEHPGAASGAQTADRMD
SLD---SHDSIS------------------------------------------------
--------SEPTQCTMLYSRQGTTETIEEVEAEQEEEAGSTAPESREAKEYE--------
-------AAGYDVGARGAEEASLTPE---EELTQFSTLDGDVEAPPSYSKAVSFEHLSFG
SQDD-SAVKNHMAVSPDDSRTD-----KLGSSILPPLTHELTASELLLKKMFHDDE--LE
ESEKFYVGQPRFLLLFYAMYNTLVARSEMVCYFVIILNHMVSASMITLLLPILIFLWAML
SVPRPSRRFWMMAIVYTEVAIVVKYFFQFGFFPWNKNVEV--NRDKPFHPPNIIGVEKKE
GYVLYDLIQLLALFFHRS--ILKCHGLWDEDDMTESGMDKEESDDEL---SLGHGRRDSS
---DSLKSINLAASVES-----------------VHVTFPEQQTAVRRKR--SGSSSEPS
QRSSFSSNRSQR-----GST-STRNSSQKG--SSVLSIK-----QKSKRELY-MEKLQEH
LIKAKAF----------------TIKKTLQIYVPIKQFFYNLIHPDYSAVTDVYVLMFLA
DTVDFIIIVFGFWAFGK-HSAAADITSSLSEDQVPGPFLVMVLIQFGTMVVDRALYLRKT
VLGKVIFQVILVFGIHFWMFFILPGVTERKFSQNLVAQLWYFVKCVYFGLSAYQIRCGYP
TRVLGNFLTKSYNYVNLFLFQGF

PF12166 // ENSGT00390000013029_1_Domain_2 (2664, 2702)

RLVPFLTELRAVMDWVWTDTTLSLSSWICVEDIYAHI
F

ENSGT00390000013029_1_Linker_2_3 (2702, 2775)

I----------------------------------------------------------
--------------

PF12166 // ENSGT00390000013029_1_Domain_3 (2775, 3095)

PIFTMSAQQSQLKVMDQQNFNKFIQA-----FSRDTGAMQFLENYE
KEDITVAELEGNSNSLWTISPPSKQKMIHELLDPNSSFSVVFSWSIQRNLSLGAKSEIAT
DKLSFPLKNITRKNIAKMIAGNSTESSKTPVTIEKIYPYYVKAPSDSNSKPIKQLLS--E
NNFMDITI-------------ILSRDNTTKYNSEWWVLNLTGNRIYNPNSQALELVVFND
KVSPPSLGFLAGYGIMGLYASVVLVIGKFVREFFSGISHSIMFEELPNVDRILKLCTDIF
LVRETGELELEEDLYAKLIFLYRSPETMIKWTREKTN

----------MASEVVCGLIFRLLLPICLAVACAFRYNGLSFVYLIYLLLIPLFSEPTKT
T------MQGHTGRLLKSLCFISLSFLLLHIIFHIT-----LVSLEAQHRIAPGYN----
--------------LKGADAGNGIRVFVPDIGMFIASLTIWLLCRNIVQKPVTDEAAQSN
PEFENEELAGGEKIDSEEALIYE-EDFNGGDGVEGELEESTKLKMFRRLASVASKLKEFI
GNMITTAGKVVVTILLGS-SGMMLPSLTSSVYFFVFLGLCTWWSWCRTFDPLLFSCLCVL
LAIFTAGHLIGLYLYQFQFFQEAVPPNDYYA-RLFGIKSVIQTDCSSTWKIIVNPDLSWY
HHANPILLLVMYYTLATLI-RIWLQEPL--VQDEGTK------EEDKALACSPIQI-TAE
RRRSLWYATHYPTDERKLLSMTQDDYKPSDGLLVTVNGNPVDYHTIHPSLPMENGPGKAD
LYSTPQYRWEPSDESSEKREE-EEEEKEEFEEERSREEKRSIKVHAMVSVFQFIMKQSYI
CALIAMM-AWSITYHSWLTFVLLIWSCTLWMIRNRRKYAMISSPFMVVYGNLLLILQYIW
SFELP--EIKKVPGFLEKKEPGELAS---------KILFTITFWLLLRQHLTEQKALQEK
EALLSEVKIGSQENEEK-----DEELQDIQV---EAEPKEE-------------------
-----EE-EEAKEEKQERKKIEQEE---AEEEDEQDIMKVLGNLVVAMFIKYWIYVCGGM
FFFVSFEGKIVMYKIIYMVLFLFCVALYQVHYEWWRKILKYFWMSVVIYTMLVLIFIYTY
QFENFPGLWQNMTGLKKEKLEDLGLKQFTVAELFTRIFIPTSFLLVCILHLHYFHDRFLE
LTDLKSIPSKEDNTIYSHAKVNGRVYLIINSIKKKLPIHQNELAHPEGSLPDLTMMHLTA
SLEKPEVRKLAEPGEEKPEGYSEKAQ--KGDLGKDSEESEEDGE-EE-----EESEE-EE
ETSDLRNKWHLVIDRLTVLFLKFLEYFHKLQVFMWWILELHIIKIVSSYIIWVSVKE--V
SLFNYVFLISWAFALPYAKLRRLASSVCTVWTCVIIVCKMLYQLQTIKPENFSVNCSLPN
ENQTNIP-FNELNKSLLYSAP-IDPTEWVGLRKSSPLLVYLRNNLLMLAILAFEVTIYRH
QEYYRGRNNLTAPVSRTIFHDITRLHLDDGLINCAKYFINYFFYKFGLETCFLMSVNVIG
QRMDFYAMIHACWLIAVLYRRRRKAIAEIWPKYCCFLACIITFQYFICIGIPPAPCRDYP
WRFKGASFNDNIIKWLYFPDFIVRPNPVFLVYDFMLLLCASLQRQIFEDENKAAVRIMAG
DNVEICMNLDAASFSQHNPVPDFIHC-RSYLDMSKVIVFSYLFWFVLTIIFITGTTRISI
FCMGYLVACFYFLLFGGDLLLKPIKSILRYWDWLIAYNVFVITMKNILSIG

PF15917 // ENSGT00390000013029_1_Domain_0 (1492, 1775)

ACGYIGTLV
HNSCWLIQAFSLACTVKGYQ--------MPAANSPCTLPSGEAGIIWDSICFAFLLLQRR
VFMSYYFLHVVA--------DIKASQILASRGAELFQATIVKAVKARIEEEKKSMDQLKR
QMDRIKARQQKYKKGKERMLSLTQEPGEGQDMQKLSEEDDE-READKQKAKGKKKQWWRP
WVDHASMVRSGDYYLFETDSEEEEEEELKKEDEEPPRRSAF-------------------
--------------QFVYQAWITDPKTALRQRHK

ENSGT00390000013029_1_Linker_0_3 (1775, 2665)

EKKRSAREERKRRRKGSKEGP--VEW
EDREDEPIKKKSDGPDNIIKRIFNILKFTWVLFLATVDSFTTWLNSISREHIDISTVLRI
ERCMLTREIKKGN-VPTRESI-HMYYQNHI-MNLSRESGLDTIDEHPGAASGAQTAHRMD
SLD---SHDSIS------------------------------------------------
--------SEPTQCTMLYSRQGTTETIEEVEAEQEEEAGSTAPEPREAKEYE--------
-------ATGYDVGAMGAEEASLTPE---EELTQFSTLDGDLEAPPSYSKAVSFEHLSFG
SQDD-SAGKNHMAVSPDDSRTD-----KLGSSILPPLTHELTASELLLKKMFHDDE--LE
ESEKFYVGQPRFLLLFYAMYNTLVARSEMVCYFVIILNHMVSASMITLLLPILIFLWAML
SVPRPSRRFWMMAIVYTEVAIVVKYFFQFGFFPWNKNVEV--NKDKPYHPPNIIGVEKKE
GYVLYDLIQLLALFFHRS--ILKCHGLWDEDDMTESGMDKEESDDEL---SLGHGRRDSS
---DSLKSINLAASVES-----------------VHVTFPEQQTAVRRKR--SGSSSEPS
QRSSFSSNRSQR-----GST-STRNSSQKG--SSVLSIK-----QKSKRELY-MEKLQEH
LIKAKAF----------------TIKKTLEIYVPIKQFFYNLIHPEYSAVTDVYVLMFLA
DTVDFIIIVFGFWAFGK-HSAAADITSSLSEDQVPGPFLVMVLIQFGTMVVDRALYLRKT
VLGKVIFQVILVFGIHFWMFFILPGVTERKFSQNLVAQLWYFVKCVYFGLSAYQIRCGYP
TRVLGNFLTKSYNYVNLFLFQGFR

PF12166 // ENSGT00390000013029_1_Domain_3 (2665, 3094)

LVPFLTELRAVMDWVWTDTTLSLSSWICVEDIYAHI
FILKCWRESEKRYPQPRGQKKKKVVKYGMGGMIIVLLICIVWFPLLFMSLIKSVAGVINQ
PLDVSVTITLGGYQPIFTMSAQQSQLKVMDQQSFNKFIQA-----FSRDTGAMQFLENYE
KEDITVAELEGNSNSLWTISPPSKQKMIHELLDPNSSFSVVFSWSIQRNLSLGAKSEIAT
DKLSFPLKNITRKNIAKMIAGNSTESSKTPVTIEKIYPYYVKAPSDSNSKPIKQLLS--E
NNFLDITI-------------ILSRDNTTKYNSEWWVLNLTGNRIYNPNSQALELVVFND
KVSPPSLGFLAGYGIMGLYASVVLVIGKFVREFFSGISHSIMFEELPNVDRILKLCTDIF
LVRETGELELEEDLYAKLIFLYRSPETMIKWTREKTN

----------MASEVVCGLIFRLLLPICLAVACAFRYNGLSFVYLIYLLLIPLFSEPTKA
T------MQGHTGRLLQSLCITSLSFLLLHIIFHIT-----LASLEAQHRIAPAYNCSTW
EKTFRQIGFE---SLKGADAGNGIRVFVPDIGMFIASLTIWLVCRTIVKKPDTEEIAQLN
SECENEELAGGEKVDSEEALIYE-EDLDGEEGMEGELEESTKLKMLRRFASVASKLKEFI
GNMITTAGKVVVTILLGS-SGMMLPSLTSAVYFFVFLGLCTWWSWCRTFDPLLFGCLCVL
LAIFTAGHLIGLYLYQFQFFQEAVPPNDYYA-RLFGIKSVIQTDCSSTWKIIVNPDLSWY
HHANPILLLVMYYTLATLI-RIWLQEPL--VQEEMAK------EDEGALDCSSNQN-TAE
RRRSLWYATQYPTDERKLLSMTQDDYKPSDGLLVTVNGNPVDYHTIHPSLPIENGPAKTD
LYTTPQYRWEPSEESSEKKEE-EEDKREDSEGEGSQEEKRSVRMHAMVAVFQFIMKQSYI
CALIAMM-AWSITYHSWLTFVLLIWSCTLWMIRNRRKYAMISSPFMVVYANLLLVLQYIW
SFELP--EIKKVPGFLEKKEPGELAS---------KILFTITFWLLLRQHLTEQKALREK
EALLSEVKIGSQELEEK----EDEELQDVQV---EGEPTE--------------------
--KEEEEEEEIKE---ERHEVKKEEEEEVEEDDDQDIMKVLGNLVVALFIKYWIYVCGGM
FFFVSFEGKIVMYKIIYMVLFLFCVALYQVHYEWWRKILKYFWMSVVIYTMLVLIFIYTY
QFENFPGLWQNMTGLKKEKLEDLGLKQFTVAELFTRIFIPTSFLLVCILHLHYFHDRFLE
LTDLKSIPSKEDNTIYSHAKVNGRVYLIIN-----------RLAHPEGSLPDLAIMNMTA
SLDKPEVQKLAESGEERPEECVKKTE--KGEAGKDSDESEEEED-EE-------EESEEE
ESSDLRNKWHLVIDRLTVLFLKFLEYFHKLQVFMWWILELHIIKIVSSYIIWVTVKE--V
SLFNYVFLISWAFALPYAKLRRVASSVCTVWTCVIIVCKMLYQLQTIKPENFSVNCSLPN
ENQTNIP-LHELNKSLLYSAP-VDPTEWVGLRKSSPLLVYLRNNLLMLAILAFEVTVYRH
QEYYRGRNNLTAPVSKTIFHDITRLHLDDGLINCAKYFVNYFFYKFGLETCFLMSVNVIG
QRMDFYAMIHACWLIGVLYRRRRKAIAEVWPKYCCFLACIITFQYFVCIGIPPAPCRDYP
WRFKGAYFNDNIIKWLYFPDFIVRPNPVFLVYDFMLLLCASLQRQIFEDENKAAVRIMAG
DNVEICMNLDAASFSQHNPVPDFIHC-RSYLDMSKVIIFSYLFWFVLTIIFITGTTRISI
FCMGYLVACFYFLLFGGDLLLKPIKSILRYWDWLIAYNVFVITMKNVLSIG

PF15917 // ENSGT00390000013029_1_Domain_0 (1492, 1775)

ACGYIGALV
RNSCWLIQAFSLACTVKGYQ--------MPEDDSRCKLPSGEAGIIWDSICFAFLLLQRR
VFMSYYFLHVVA--------DIKASQILASRGAELFQATIVKAVKARIEEEKKSMDQLKR
QMDRIKARQQKYKKGKERMLSLTQESGEGQDIQKVSEEDDE-READKQKAKGKKKQWWRP
WVDHASMVRSGDYYLFETDSEEEEEEELKKEDEEPPRKSAF-------------------
--------------QFVYQAWITDPKTALRQRRK

ENSGT00390000013029_1_Linker_0_3 (1775, 2665)

EKKKLAREEQKERRKGSGDGP--VEW
EDREDEPVKKKSDGPDNIIKRIFNILKFTWVLFLATVDSFTTWLNSISREHIDISTVLRI
ERCMLTREIKKGN-VPTRESI-HMYYQNHI-MNLSRESGLDTIDEHSGAGSRAQAAHRMD
SLD---SRDSISSCYTEATLLISRQSTLDDLDGQDPVPKTSERARPRLRKMFSLDMSSSS
ADSGSVASSEPTQCTMLYSRQGTTETIEEVEAEAEEEVVECLEPELQDAEEK--------
-----EYTVE---YEAGVEEISLTPD---EELPQFSTDDGDVEAPPSYSKAVSFEHLSFA
SQDD-SGAKNHMVVSPDDSRTD-----KLESSILPPLTHELTASDLLMSKMFHDDE--LE
ESEKFYVDQPRFLLLFYAMYNTLVARSEMVCYFVIILNHMTSASIITLLLPILIFLWAML
SVPRPSRRFWMMAIVYTEVAIVVKYFFQFGFFPWNKDLEI--YKERPYFPPNIIGVEKKE
GYVLYDLIQLLALFFHRS--ILKCHGLWDEDDIVDSNTDKEGSDDEL---SLDQGRRGSS
---DSLKSINLAASVES-----------------VHVTFPEQPAAIRRKR--SCSSSQIS
PRSSFSSNRSKR-----GST-STRNSSQKG--SSVLSLK-----QKSKRELY-MEKLQEH
LIKAKAF----------------TIKKTLQIYVPIRQFFYDLIHPDYSAVTDVYVLMFLA
DTVDFIIIVFGFWAFGK-HSAAADITSSLSEDQVPGPFLVMVLIQFGTMVVDRALYLRKT
VLGKVIFQVILVFGIHFWMFFILPGVTERKFSQNLVAQLWYFVKCVYFGLSAYQIRCGYP
TRVLGNFLTKSYNYVNLFLFQGFR

PF12166 // ENSGT00390000013029_1_Domain_3 (2665, 3094)

LVPFLTELRAVMDWVWTDTTLSLSSWICVEDIYAHI
FILKCWRESEKRYPQPRGQKKKKAVKYGMGGMIIVLLICIVWFPLLFMSLIKSVAGVINQ
PLDVSVTITLGGYQPIFTMSAQQSQLKVMDNSKYKEFLNS-----FGPNSGAMQFLENYE
REDITVAELEGNSNSLWTISPPSKQKMIQELTDPNSCFSVVFSWSIQRNMTLGAKAEIAT
DKLSFPLADATRNSIAKMIAGNDTESSNTPVTIEKIYPYYVKAPSDSNSKPIKQLLS--E
NNFMNITI-------------ILFRDNVTKSNSEWWVLNLTGSRIFNQGSQALELVVFND
KVSPPSLGFLAGYGIMGLYASVVLVIGKFVREFFSGISHSIMFEELPNVDRILKLCTDIF
LVRETGELELEEDLYAKLIFLYRSPETMIKWTREKTN

------------------------------------------------------------
---------------------------------------------------------STW
EKTFRQIGF---ESLKGADAGNGIRVFVPDIGMFIASLTIWLVCRNIVQKPVTEEAAQYN
PEFENEELAGREKMDSEEALIYE-EDLDGGDGVEGELEESTKLKLFRRLASVASKLKEFI
GNMITTAGKVVVTILLGS-SGMMLPSLTSSVYFFVFLGLCTWWSWCRTFDPLLFSCLCVL
LAIFTAGHLIGLYLYQFQFFQEAVPPNDYYA-RLFGIKSVIQTDCSSTWKIIVNPDLSWY
HHANPILLLVMYYTLATLI-RIWLQEPL--VQDERTK------EEDRALACSPIQI-TAE
RRRSLWYATHYPTDERKLLSMTQDDYKPSDGLLVTVNGNPVDYHTIHPSLPMENGPGKTD
LYSTPQYRWEPSDESSEKKED-EEDEKEEFEEEWSHEEKRSVKVHAMVSVFQFIMKQSYI
CALIAMM-AWSITYHSWLTFVLLIWSCTLWMIRNRRKYAMISSPFMVVYGNLLLILQYIW
SFELP--EIKKVPGFLEKKEPGELAS---------KILFTITFWLLLRQHLTEQKALQEK
EALLSEVKIGSQENEEK-----DEELQDIQV---EGEPKEE-------------------
-----EEEEEVKEEQQERKKEEEA--ETEEEDDDQDIMKVLGNLVVAMFIKYWIYVCGGM
FFFVSFEGKIVMYKIIYMVLFLFCVALYQVHYDWWRRILKYFWMSVVIYTMLVLIFIYTY
QFENFPGLWQNMTGLKKEKLEDLGLKQFTVAELFTRIFIPTSFLLVCILHLHYFHDRFLE
LTDLKSIPSKEDNTVYSHAKVNGRVYLIINSIKKKLPIHQNELAHPEGSLPDLAMLNLTA
SLEKPEVRKLAESGEEKPEGCSEKAE--KGELGKDSEESEEDEE-EE-------EESEEE
ETSDLRNKWHLVIDRLTVLFLKFLEYFHKLQVFMWWILELHIIKIVSSYIIWVSVKE--V
SLFNYVFLISWAFALPYAKLRRLASSVCTVWTCVIIVCKMLYQLQTIKPENFSVNCSLPN
ENQTNIP-LHDLNKSLLYSAP-IDPTEWVGLRKSSPLLIYLRNNLLMLAILAFEVTIYRH
QEYYRGRNNLTAPVSKTIFHDITRLHLDDGLINCAKYFINYFFYKFGLETCFLMSVNVIG
QRMDFYAMIHACWLIAVLYRRRRKAIAEVWPKYCCFLACIITFQYFICIGIPPAPCRDYP
WRFKGADFNDNIIKWLYFPDFIVRPNPVFLVYDFMLLLCASLQRQIFEDENKAAVRIMAG
DNVEICMNLDAASFSQHNPVPDFIHC-RSYLDMSKVIIFSYLFWFVLTIIFITGTTRISI
FCMGYLVACFYFLLFGGDLLLKPIKSILRYWDWLIAYNVFVITMKNILSIG

PF15917 // ENSGT00390000013029_1_Domain_0 (1492, 1775)

ACGYIGTLV
QNSCWLIQAFSLACTVKGYK--------MPDDDSHCKLPSGEAGIIWDSICFAFLLLQRR
VFMSYYFLHVVA--------DIKASQILASRGAELFQATIVKAVKARIEEEKKSMDQLKR
QMDRIKARQQKYKKGKERMLSLTQESGEGQDIQKLSEEDDE-READKQKAKGKKKQWWRP
WVDHASMVRSGDYYLFETDSEEEEEEELKKEDEEPPRRSAF-------------------
--------------QFVYQAWITDPKTALRQRRK

ENSGT00390000013029_1_Linker_0_3 (1775, 2665)

EKKRSTRE-QKGRRKGSGEGL--VEW
ER-EEEPIKKKSDGPDNIIKRIFNILKFTWVLFLATVDSFTTWLNSISREHIDISTVLRI
ERCMLTREIKKGN-VPTRESI-HMYYQNHI-MNLSRESGLDTIDEHPGAALGPQTAHRMD
SLD---SHDSIS------------------------------------------------
--------SEPTQCTMLYSRQGTTETIEEVEAEQEEEAGDLVAEPGEAEE----------
-------EYEAEYDASGTEEAGLTPE---EDLTQFSTLDADVEAPPSYSKAVSFEHLSFS
SQDD-SAGKNRMVVSPDDSRTD-----KLESSILPPLTHELTASELLLNKMFHDDE--LE
ESEKFYVGQPRFLLLFYAMYNTLVARSEMVCYFVIILNHMVSASVITLLLPILIFLWAML
SVPRPSRRFWMMAIVYTEVAIVVKYFFQFGFFPWNKDVER--HKDKPYHPANIIGVEKKE
GYVLYDLIQLLALFFHRS--ILKCHGLWDEDDILESGMDKEETDDEL---SL--GRRDSS
---DSLKSINLAASAES-----------------VHVTFPEQQMAIRRKR--SSSSSQIS
QTSSFSSNRSKR-----GST-STRNSSQKG--SSVLSVK-----QKSKKELY-MEKLQEH
LIKAKAF----------------TIKKTLQIYVPIRQFFYDLIHPDYSAVTDVYVLMFLA
DTVDFIIIVFGFWAFGK-HSAATDITSSLSEDQVPGPFLVMVLIQFGTMVVDRALYLRKT
VLGKVIFQVILVFGIHFWMFFILPGVTERKFSQNLVAQLWYFVKCVYFGLSAYQIRCGYP
TRVLGNFLTKSYNYVNLFLFQGFR

PF12166 // ENSGT00390000013029_1_Domain_3 (2665, 3094)

LVPFLTELRAVMDWVWTDTTLSLSSWICVEDIYAHI
FILKCWRESEKRYPQPRGQKKKKVVKYGMGGMIIVLLICIVWFPLLFMSLIKSVAGVINQ
PLDVSVTITLGGYQPIFTMSAQQSKLKVMDQSKFNSFIRS-----FSRDTGAMQFLENYE
KEDITVAELEGNSNSLWTISPPSKQKMINELMEPNSSFSVVFSWSIQRNLSLGAKAEIAT
DKLSFPLKNITRKNIAKMIDGNNTESSKTPVTIEKIYPYYVKAPSDSNSKPIKQLLS--E
NNFMDITI-------------ILSRDNMTKSNSEWWVLNLTGNRIYNQQSQALELVVFND
KVSPPSLGFLAGYGIMGLYASVVLVIGKFVREFFSGISHSIMFEELPNVDRILKLCTDIF
LVRETGELELEEDLYAKLIFLYRSPETMIKWTREKTN

------------------------------------------------------------
----------HTGRLLKSLCFTSLSFLLLHIIFHIT-----LASLEAQHRIAPGYNCSTW
EKTFRQIGF--ES-LKGADAGNGIRVFVPDIGMFIASLTIWLLCRNIVQKPVTDEAAQCN
LEFENEELAEGEKIDSEEALIYE-EDLDGGDGVEGELEESTKLKMFRRLASVASKLKEFI
GNMITTAGKVVVTILLGS-SGMMLPSLTSSVYFFVFLGLCTWWSWCRTFDPLLFSCLCVL
LAIFTAGHLIGLYLYQFQFFQEAVPPNDYYA-RLFGIKSVIQTDCSSTWKIIVNPDLSWY
HHANPILLLVMYYTLATLI-RIWLQEPL--VQDERTK------EEDRALACSPIQI-TAE
RRRSLWYATHYPTDERKLLSMTQDDYKPSDGLLVTVNGNPVDYHTIHPTLPMENGPGKAD
LYSTPQYRWEPSDESSEKPEE-EEEEKEEFEEERSREEKRSIKVHAMVSVFQFIMKQSYI
CALIAMM-AWSITYHSWLTFVLLIWSCTLWMIRNRRKYAMISSPFMVVYGNLLLILQYIW
SFELP--EIKKVPGFLEKKEPGELAS---------KILFTITFWLLLRQHLTEQKALQEK
EALLSEVKIGSQENEEK-----DEELQDIQV---EGEPKEK-------------------
-----EEEEEAKEEKQERRKANEEE---VEEEDEQDIMKVLGNLVVAMFIKYWIYVCGGM
FFFVSFEGKIVMYKIIYMVLFLFCVALYQVHYEWWRKILKYFWMSVVIYTMLVLIFIYTY
QFENFPGLWQNMTGLKKEKLEDLGLKQFTVAELFTRIFIPTSFLLVCILHLHYFHDQFLE
LTDLKSIPSKEDNTIYSHAKVNGRVYLIINSIKKKLPIHQNELAHPEGSLPDLTMMHLTA
SLEKPELRKLAEPGEEKPEGYSEKAQ--KGELGKDSEESEEDGE-EE-----EESEE-EE
ETSDLRNKWHLVIDRLTVLFLKFLEYFHKLQVFMWWILELHIIKIVSSYIIWVSVKE--V
SLFNYVFLISWAFALPYAKLRRLASSVCTVWTCVIIVCKMLYQLQTIKPENFSVNCSLPN
ENQTNIP-LNELNKSLLYRAP-TDPTEWVGLRKSSPLLVYLRNNLLMLAILAFEVTIYRH
QEYYRGRNNLTAPVSKTIFHDITRLHLDDGLVNCAKYFINYFFYKFGLETCFLLSVNVIG
QRMDFYAMVHACWLIAVLYRRRRKAIAEIWPKYCCFLACIITFQYFICIGIPPAPCRDYP
WRFKGASFNDNIIKWLYFPDFIVRPNPVFLVYDFMLLLCASLQRQIFEDENKAAVRIMAG
DNVEICMNLDAASFSQHNPVPDFIHC-RSYLDMSKVIVFSYLFWFVLTIIFITGTTRISI
FCMGYLVACFYFLLFGGDLLLKPIKSILRYWDWLIAYNVFVITMKNILSIG

PF15917 // ENSGT00390000013029_1_Domain_0 (1492, 1775)

ACGYIGTLV
HNSCWLIQAFSLACTVKGYQ--------MPPANSPCTLPSGEAGIIWDSICFAFLLLQRR
VFMSYYFLHVVA--------DIKASQILASRGAELFQATIVKAVKARIEEEKKSMDQLKR
QMDRIKARQQKYKKGKERMLSLTQEPGEGQDMQKLSEEDDE-READKQKAKGKKKQWWRP
WVDHASMVRSGDYYLFETDSEEEEEEELKKEDEELPRRSAF-------------------
--------------QFVYQAWITDPKTALRQRHK

ENSGT00390000013029_1_Linker_0_3 (1775, 2665)

EKKRSAREERKRRRKGSKESP--VEW
EDREDEPIKKKSDGPDNIIKRIFNILKFTWVLFLATVDSFTTWLNSISREHIDISTVLRI
ERCMLTREIKKGN-VPTRESI-HMYYQNHI-MNLSRESGLDTIDEHPGAASGAQTAHRMD
SLD---SHDSIS------------------------------------------------
--------SEPTQCTMLYSRQGTTETIEEVEAEQEEEAGSTMPESGEAKEYE--------
-------AAGYDVGAVGAEEVSLTPE---EELTQFSTLEGDVEAPPSYSKAVSFEHLSFG
SQDD-STGKNHMAVSPDDSRTD-----KLGSSILPSLTHELTASELLLNKMFHDDE--LE
ESEKFYVGQPRFLLLFYAMYNTLVARSEMVCYFVIILNHMVSASMITLLLPILIFLWAML
SVPRPSRRFWMMAIVYTEVAIVVKYFFQFGFFPWNKTAEL--NKDKPYHPPNIIGVEKKE
GYVLYDLIQLLALFFHRS--ILKCHGLWDEDDMTESGMDKEESDDEL---SLSHGRRDSS
---DSLKSINLAASVES-----------------VHVTFPEQQTAVRRKR--SSTNSEPS
QRSSFSSIRSQR-----GST-STRNSSQKG--SSVLSIK-----QKSKRELY-MEKFQEH
LIKAKAF----------------TIKKTLQMYVPIRQFFYNLIHPDYSAVTDVYVLMFLA
DTVDFIIIVFGFWAFGK-HSAAADITSSLSEDQVPGPFLVMVLIQFGTMVVDRALYLRKT
VLGKVIFQVILVFGIHFWMFFILPGVTERKFSQNLVAQLWYFVKCVYFGLSAYQIRCGYP
TRVLGNFLTKSYNYVNLFLFQGFR

PF12166 // ENSGT00390000013029_1_Domain_3 (2665, 3094)

LVPFLTELRAVMDWVWTDTTLSLSSWICVEDIYAHI
FILKCWRESEKRYPQPRGQKKKKVVKYGMGGMIIVLLICIVWFPLLFMSLIKSVAGVINQ
PLDVSVTITLGGYQPIFTMSAQQSQLKVMDQQNFNKFIRA-----FSRDTGAMQFLENYE
KEDITVAELEGNSNSLWTISPPSKEKMIHELLDPNSSFSVVFSWSIQRNLSLGAKAEIAT
DKLSFTLQNSTRKNIAKMIAGNNTESSKTPVTIEKIYPYYVKAPSDSNSKPIKQLLS--E
NNFMDITI-------------ILSRDNTTKYNSEWWVLNLTGNRIYNPESQALELVVFND
KVSPPSLGFLAGYGIMGLYASVVLVIGKFVREFFSGISHSIMFEELPNVDRILKLCTDIF
LVRETGELELEEDLYAKLIFLYRSPETMIKWTREKTN

-------------------------------MCR--------------------------
------------------FCETLRSIKSFRVPFREKLSIFYFKSLRRPKHPIRRFNHRNI
RTKFSPLPLFFLYSLKGADAGNGIRVFVPDIGMFIASLTIWLLCRNIVQKPVTDEAAQSN
PEFENEELAGGEKIDSEEALIYE-EDFNGGDGVEGELEESTKLKMFRRLASVASKLKEFI
GNMITTAGKVVVTILLGS-SGMMLPSLTSSVYFFVFLGLCTWWSWCRTFDPLLFSCLCVL
LAIFTAGHLIGLYLYQFQFFQEAVPPNDYYA-RLFGIKSVIQTDCSSTWKIIVNPDLSWY
HHANPILLLVMYYTLATLI-RIWLQEPL--VQDEGTK------EEDKALACSPIQI-TAE
RRRSLWYATHYPTDERKLLSMTQDDYKPSDGLLVTVNGNPVDYHTIHPSLPMENGPGKAD
LYSTPQYRWEPSDESSEKREE-EEEEKEEFEEERSREEKRSIKVHAMVSVFQFIMKQSYI
CALIAMM-AWSITYHSWLTFVLLIWSCTLWMIRNRRKYAMISSPFMVVYGNLLLILQYIW
SFELP--EIKKVPGFLEKKEPGELAS---------KILFTITFWLLLRQHLTEQKALQEK
EALLSEVKIGSQENEEK-----DEELQDIQV---EGEPKEE-------------------
-----EE-EEAKEEKQERKKVEQEE---AEEEDEQDIMKVLGNLVVAMFIKYWIYVCGGM
FFFVSFEGKIVMYKIIYMVLFLFCVALYQVHYEWWRKILKYFWMSVVIYTMLVLIFIYTY
QFENFPGLWQNMTGLKKEKLEDLGLKQFTVAELFTRIFIPTSFLLVCILHLHYFHDRFLE
LTDLKSIPSKEDNTIYR-------------------------LAHPEGSLPDLTMMHLTA
SLEKPEVRKLAEPGEEKPEGYSEKAQ--KGDLGKDSEESEEDGE-EE-----EESEE-EE
ETSDLRNKWHLVIDRLTVLFLKFLEYFHKLQVFMWWILELHIIKIVSSYIIWVSVKE--V
SLFNYVFLISWAFALPYAKLRRLASSVCTVWTCVIIVCKMLYQLQTIKPENFSVNCSLPN
ENQTNIP-FNELNKSLLYSAP-IDPTEWVGLRKSSPLLVYLRNNLLMLAILAFEVTIYRH
QEYYRGRNNLTAPVSRTIFHDITRLHLDDGLINCAKYFINYFFYKFGLETCFLMSVNVIG
QRMDFYAMIHACWLIAVLYRRRRKAIAEIWPKYCCFLACIITFQYFICIGIPPAPCRDYP
WRFKGASFNDNIIKWLYFPDFIVRPNPVFLVYDFMLLLCASLQRQIFEDENKAAVRIMAG
DNVEICMNLDAASFSQHNPVPDFIHC-RSYLDMSKVIVFSYLFWFVLTIIFITGTTRISI
FCMGYLVACFYFLLFGGDLLLKPIKSILRYWDWLIAYNVFVITMKNILSIG

PF15917 // ENSGT00390000013029_1_Domain_0 (1492, 1775)

ACGYIGTLV
HNSCWLIQAFSLACTVKGYQ--------MPAANSPCTLPSGEAGIIWDSICFAFLLLQRR
VFMSYYFLHVVA--------DIKASQILASRGAELFQATIVKAVKARIEEEKKSMDQLKR
QMDRIKARQQKYKKGKERMLSLTQEPGEVQDMQKLSEEDDE-------------------
------MVRSGDYYLFETDSEEEEEEELKKEDEEPPRRSAF-------------------
--------------QFVYQAWITDPKTALRQRHK

ENSGT00390000013029_1_Linker_0_3 (1775, 2665)

EKKRSAREERKRRRKGSKEGP--VEW
EDREDEPIKKKSDGPDNIIKRIFNILKFTWVLFLATVDSFTTWLNSISREHIDISTVLRI
ERCMLTREIKKGN-VPTRESI-HMYYQNHI-MNLSRESGLDTIDEHPRAASGAQTAHRMD
SLD---SHDSIS------------------------------------------------
--------SEPTQCTMLYSRQGTTETIEEVEAEQEEEAGSMAPEPREAKEYE--------
-------ATGYDVGAMGAEEASLTPE---EELTQFSTLDGDVEAPPSYSKAVSFEHLSFG
SQDD-SAGKNHMAVSPDDSRTD-----KLGSSILPPLTHELTASELLLKKMFHDNE--LE
ESEKFYVGQPRFLLLFYAMYNTLVARSEMVCYFVIILNHMVSASMITLLLPILIFLWAML
SVPRPSRRFWMMAIVYTEVAIVVKYFFQFGFFPWNKNVEV--NKDKPYHPPNIIGVEKKE
GYVLYDLIQLLALFFHRS--ILKCHGLWDEDDMTESGMDKEESDDEL---SLGHGRRDSS
---DSLKSINLAASVES-----------------VHVTFPEQQTAVRRKR--SGSSSEPS
QRSSFSSNRSQR-----GST-STRNSSQKG--SSVLSTK-----QKSKRELY-MEKIQEH
LIKAKAF----------------TIKKTLEIYVPIKQFFYNLIHPEYSAVTDVYVLMFLA
DTVDFIIIVFGFWAFGK-HSAAADITSSLSEDQVPGPFLVMVLIQFGTMVVDRALYLRKT
VLGKVIFQVILVFGIHFWMFFILPGVTERKFSQNLVAQLWYFVKCVYFGLSAYQIRCGYP
TRVLGNFLTKSYNYVNLFLFQGFR

PF12166 // ENSGT00390000013029_1_Domain_3 (2665, 3094)

LVPFLTELRAVMDWVWTDTTLSLSSWICVEDIYAHI
FILKCWRESEKRYPQPRGQKKKKVVKYGMGGMIIVLLICIVWFPLLFMSLIKSVAGVINQ
PLDVSVTITLGGYQPIFTMSAQQSQLKVMDQQSFNKFIQA-----FSRDTGAMQFLENYE
KEDITVAELEGNSNSLWTISPPSKQKMIHELLDPNSSFSVVFSWSIQRNLSLGAKSEIAT
DKLSFPLKNITRKNIAKMIAGNSTESSKTPVTIEKIYPYYVKAPSDSNSKPIKQLLS--E
NNFMDITI-------------ILSRDNTTKYNSEWWVLNLTGNRIYNPNSQALELVVFND
KVSPPSLGFLAGYGIMGLYASVVLVIGKFVREFFSGISHSIMFEELPNVDRILKLCTDIF
LVRETGELELEEDLYAKLIFLYRSPETMIKWTREKTN

----------MASEVVCGLIFRLLLPICLAVACAFRYNGLSFVYLIYLLLIPLFSEPTKA
T------MQGHTGRLLKSLCFTSLSFLLLHIIFHIT-----LASLEAQHRIGPGYNCSTW
EKTFRQIGFE---SLKGADAGNGIRVFVPDIGMFIASLTIWLVCRNIVQKPGTEEAAQYN
SEFENEELAGGEKLDAEEALIYE-EDLDEGDGVEGDVEESTKLKMFRRLASVASKLKEFI
GNMITTAGKVVVTILLGS-SGMMLPSLTSSVYFFVFLGLCTWWSWCRTFDPLLFSCLCVL
LAIFTAGHLIGLYLYQFQFFQEAVPPNDYYA-RLFGIKSVIHTDCSSTWKIIANPDLSWY
HHANPIVLLVMYYTLATLI-RIWLQEPL--VQDDRTKE------EDRALACSPIQI-TAE
RRRSLWYATHYPTDERKLLSMTQDDYKPSDGLLVTVNGNPVDYHTIHPSLPIENGPAKAE
LYSTPQYRWQPSEDSSEKKEE-EEDEKEEFEEERSHEEKRSIKVHAMVSVFQFIMKQSYI
CALIAMM-AWSITYHSWLTFVLLIWSCTLWMIRNRRKYAMISSPFMVVYGNLLLILQYIW
SFELP--EIKKVPGFLEKKEPGELAS---------KILFTITFWLLLRQHLTEQKALQEK
EALLSEIKIGSQENEEK-----DD-EQDIQTE---GEPEEKEE-EEAKEEKQE-------
-------------------RR-KEEEEEVEEDDDQDIMKVLGNLVVAMFIKYWIYVCGGM
FFFVSFEGKIVMYKIIYMVLFLFCVALYQVHYEWWRRILKYFWMSVVIYTMLVLIFIYTY
QFENFPGLWQNMTGLKKEKLEDLGLKQFTVAELFTRIFIPTSFLLVCILHLHYFHDRFLE
LTDLKSIPSKEDSAIYSIKK---KLPIHQN-----------ELAHPEGSLPDLAMMNLTA
SLEKPDIRKLAEPGDDKSEGCPYKAEK--AEL--GKDSEEEEEEE--EE--EEEEEDEEE
ETSDLRNKWHLVIDRLTVLFLKFLEYFHKLQVFVWWILELHIIKIVSSYIIWVSVKE--V
SLFNYVFLISWAFALPYAKLRRLASSVCTVWTCVIIVCKMLYQLQTIKPENFSVNCSLPN
ENQTNIP-IHQLNKSQLYSAP-IDPTEWVGLRKSSPLLVYLRNHLLMLAILAFEVTIYRH
QEYYRGRNNLTAPVSKTIFHDITRLHLDDGLINCAKYFINYFFYKFGLETCFLMSVNVIG
QRMDFYAMIHACWLIAVLYRRRRKAIAEIWPKYCCFLACIITFQYFICIGIPAAPCRDYP
WRFKGASFNDNIIKWLYFPDFIVRPNPVFLVYDFMLLLCASLQRQIFEDENKAAVRIMAG
DNVEICMNLDAASFSQHNPVPDFIHC-RSYLDMSKVIIFSYLFWFVLTIIFITGTTRISI
FCMGYLVACFYFLLFGGDLLLKPIKSILRYWDWLIAYNVFVITMKNILSIGACGYIEKLV
QNSCWLIQAFSLACTVKGYKM--------PDDDSSCKLPSGEAGIIWDSICFAFLLLQRR
VFMSYYFLHVVA--------DIKASQILASRGAELFQATIVKAVKARIEEEKKSMDQLKR
QMDRIKARQQKYKKGKERMLSLTQESGEGQDIQKLSEEDDE-READKQKAKGKKKQWWRP
WVDHASMVRSGDYYLFETDSEEEEEEELKKEDEEPPRRSAF-------------------
--------------QFVYQAWITDPKTALRQRRKEKKRSAREEQKRRRKGSGEGP--VEW
EDREQEPIKKKSDGPDNIIKRIFNILKFTWVLFLATVDSFTTWLNSISREHIDISTVLRI
ERCMLTREIKKGN-VPTRESI-HMYYQNHI-MNLSRESGLDTIDDRAGAASAAQTAHRMD
SLD---SHDSIS------------------------------------------------
--------SEPTQCTMLYSRQGTTETIAEVEAEQDDEAAA-GDADQSGEATA--------
-----DMGPEEASEVSEASEVGL--TP-DAELPQYSTEDGDVEAPPSYSKAVSFERLSFG
-SRDDSAGQSHMAVSPDDS-----RSDRLESSILPPLTHELTASELLLNKMFHDDE--LE
ESEKFYVGQPRFLLLFYAMYNTLVARSEMVCYFVIILNHMVSASMITLVLPILIFLWAML
SVPRPSRRFWMMAIVYTEVAIVVKYFFQFGFFPWNKNVEL--NKDKPYHPPNIIGVEKKE
GYVLYDLIQLLALFFHRS--ILKCHGLWDEDDITDSGTDKEESEDELSLS---RGRRASS
---DSLKSINLAASAE--------S---------VHVSFPEQP-SAI-RRKRSGSSSQIS
PRSSFSSNRSQR-----GS-TSTRNSSQKG--SSVLSIK-----QKSKRELY-MEKLQE-
--------------H-LIKAKAFTIKKTLQIYVPIRQFFYDLIHPDYSAVTDVYVLMFLA
DTVDFVIIVFGFWAFGK-HSAAADITSSLSEDQVPGPFLVMVLIQFGTMVVDRALYLRKT
VLGKVIFQVILVFGIHFWMFFILPGVTERKFSQNLVAQLWYFVKCVYFGLSAYQIRCGYP
TRVLGNFLTKSYNYVNLFLFQGF

PF12166 // ENSGT00390000013029_1_Domain_3 (2664, 3095)

RLVPFLTELRAVMDWVWTDTTLSLSSWICVEDIYAHI
FILKCWRESEKRYPQPRGQKKKKVVKYGMGGMIIVLLICIVWFPLLFMSLIKSVAGVINQ
PLDVSVTITLGGYQPIFTMSAQQSQLKVMDQLKFNKFMKA-----FSRDTGAMQFLENYE
KEDITVAELEGNSNSLWTISPPSKQKMIEELMDPNSSFSVVFSWSIQRNMSLGAKAEIAT
DKLSFPLKNNTRKNIAKMIAGNNTESSRTPVTIERIYPYYVKAPSDSNSKPIKQLLS--E
NNFMNITI-------------ILSRDNTTKSNSEWWVLNLTGNRIYNQHAQALELVVFND
KVSPPSLGFLAGYGIMGLYASVVLVIGKFVREFFSGISHSIMFEELPNVDRILKLCTDIF
LVRETGELELEEDLYAKLIFLYRSPETMIKWTREKTN

----------MASEVVCGLIFRLLLPICLAVACAFRYNGLSFVYLIYLLLIPLFSEPTKA
T------MQGHTGRLLKSLCFTSLSFLLLHIIFHIT-----LASLEAQHRIGPGYNCSTW
EKTFRQIGFE---SLKGADAGNGIRVFVPDIGMFIASLTIWLVCRNIVQKPVTEEGAQYN
SEFENEELAGGEKIDPEEALIYE-EDLDEGDGVEGEVEESTKLKMFRRLASVASKLKEFI
GNMITTAGKVVVTILLGS-SGMMLPSLTSSVYFFVFLGLCTWWSWCRTFDPLLFSCLCVL
LAIFTAGHLIGLYLYQFQFFQEAVPPNDYYA-RLFGIKSVIQTDCSSTWKIVANPDLSWY
HHANPIVLLVMYYTLATLI-RIWLQEPL--VQDDRTK------EEDRALACSPIQI-TAE
RRRSLWYATQYPTDERKLLSMTQDDYKPSDGLLVTVNGNPVDYHTIHPSLPVENGPAKAD
LYSTPQYRWEPSEDSSEKKEE-EGEEKEDFEEERSHEEKRSVKVHAMVSVFQFIMKQSYI
CALIAMM-AWSITYHSWLTFVLLIWSCTLWMIRNRRKYAMISSPFMVVYGNLLLILQYIW
SFELP--EIKKVPGFLEKKEPGELAS---------KILFTITFWLLLRQHLTEQKALQEK
EALLSEVKIRSQENEGK----GK--LGE---------EA----KEEKQ------------
----------------ER---RKEEEEEMEEDDNQDIMKVLGNLVVAMFIKYWIYVCGGM
FFFVSFEGKIVMYKIIYMVLFLFCVALYQVHYEWWRRILKYFWMSVVIYTMLVLIFIYTY
QFENFPGLWQNMTGLKKEKLEDLGLKQFTVAELFTRIFIPTSFLLVCILHLHYFHDRFLE
LTDLKSIPSKEDSAIYSLLL-------WS-----------GRLAHPEGSLPDLAMMNLTA
SLEKPDLKKLAESGEDKPEECPEKAELGKDSE--E-------EE--------EGEEEEEE
ETSDLRNKWHLVIDRLTVLFLKFLEYFHKLQVFMWWILELHIIKIVSSYIIWVSV--KEV
SLFNSVFLISWAFALPYAKLRRLASSVCTVWTCVIIVCKMLYQLQTIKPENFSVNCSLPN
ENQTNIPI-HQLNKSQLYSTP-IDPTEWVGLRKSSPLLVYLRNNLLMLAILAFEVTIYRH
QEYYRGRNNLMAPVSKTIFHDITRLHLDDGLINCAKYFINYFFYKFGLETCFLMSVNVIG
QRMDFYAMIHACWLIAVLYRRRRKAIAEIWPKYCCFLACIITFQYFICIGVPPAPCRDYP
WRFKGASFNDNIIKWLYFPDFIVRPNPVFLVYDFMLLLCASLQRQIFEDENKAAVRIMAG
DNVEICMNLDAASFSQHNPVPDFIHC-RSYLDMSKVIIFSYLFWFVLTIIFITGTTRISI
FCMGYLVACFYFLLFGGDLLLKPIRSILRYWDWLIAYNVFVITMKNILSIG

PF15917 // ENSGT00390000013029_1_Domain_1 (1492, 1591)

ACGYIEKLV
QNSCWLIQAFSLACTVKGYKMPD--------DDSSCKLPSGEAGIIWDSICFAFLLLQRR
VFMSYYFLHVVA--------DIKASQILASRWGLNFSRPQL-------------------
------------------------------------------------------------
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-------------------------------------

----------------------------------------------------FFS-----
-----KKFYGSDSALSALRCLGVTAWKFLVCSNHIC--LGSIPRKRGTDSVSPSITGSTW
EKTFRQIGFE---SLKGADAGNGIRVFAPDIGVFLASLAIWLVCRSMVQKPVLEEAAQDS
LELENEELARGEKMDSKEALIDN-EDLDGGDREDGELGDGTRLQLLRQLASGASRLKELV
GNMITTAGKVVVTILLGS-SGMMLPSLTSAVYFFVFLGLCTWWSWCRTFDPLLFSCLCVL
LAIFTAGHLIGLYLYQFQFFQEAVPPNDYYA-RLFGIKSVIQTDCSSTWKIIVSPNLSWY
HHANPILLLVMYYTLATLI-RIWLQEPL--VPEELAK------DED--LGDSPNQH-SAE
RRRSLWYAAHYPTDERKLLSMTQDDYKPSDGLLVTVNGNPVDYHTIHPSLPLENGPAKAD
LYSTPHYRWEPSEESTEKKED-EEGEQEGSEEQRSQEDKRSVRVHAMVSVFHFIMKQSYI
CALIAMM-AWSITYHSWLTFVLLIWSCTLWMIRNRRKYAMISSPFMVAYANLLLVLQYIW
SFELP--EIKKVPGFLEKKEPGELAS---------KILFTITFWLLLRQHLTEQKALREK
EALLSEVTTGSQQPEER-----DEELQDVHSPSVEGESTEN-------------------
-----EEE---EGVNEEKQERRKEEEEVEEEDDDQDIMKVLGNLVVAMFIKYWIYVCGGM
FFFVSFEGKIVMYKIIYMVLFLFCVALYQVHYEWWRKILKYFWMSVVIYTMLVLIFIYTY
QFENFPGLWQNMTGLKKEKLEDLGLKQFTVAELFTRIFIPTSFLLVCILHLHYFHDRFLE
LTDLKSIPSKEDSAIYSHAKVNGRVYLIINRWVLLCFLFCLV---------NNCL--LHV
KLSRPEG-------------------PGKGEPGRASEEEEEGPD-DE----------EDG
DEAGDEDEWHLVIDRLTVLFLRFLEYFHKLQVFMWWILELHIIKVVSSYIIWVSVKE--V
SLFNYVFLICWAFALPYAKLRRLASSVCTVWTCVIIVCKMLYQLQTIKPSTFSISCAWPN
ESQTNIP-LNELNKSLLYSAP-IDPTEWVGLRKSSPLLVYLRNNLLMLAILAFEVTIYRH
QEYYRGRNNLTAPVSKTIFHDITRLHLDDGLVNCAKYFVNYFFYKFGLETCFLMSVNVIG
QRMDFYAMLHACWLIGVLYRRRRKAIAEVWPKYCCFLACILTLQYLVCIGVPPAPCRDYP
WRLKGANFNDNIIKWLYFPDFIVRPNPVFLVYDFMLLLCASLQRQIFEDENKAAVRIMAG
DNVEICMSLDAASFSQHNPVPDFIHC-RSYLDMSKVVIFSHLFWFVLTIIFITGTTRISI
FCMGYLVACFYFLLFGGDLLLRPIRSILRYWDWLIAYNVFVITMKNVLSIG

PF15917 // ENSGT00390000013029_1_Domain_0 (1492, 1775)

ACGYIGTLV
KKSCWLIQAFSLACTVKGYQ--------MPSDDSSCKLPSGEAGIIWDSICFAFLLLQRR
VFMSYYFLHVVA--------DIKASQILASRGAELFQATIVKAVKARIEEEKKSMDQLKR
QMDRIKARQQKYKKGKERMLSVTQESGEGQDTQRLSEEDDE-READKQKAKGKKKQWWRP
WVDHASMVRSGDYYLFETDSEEEEEEEQKKEDEEPPRKSAF-------------------
--------------QFVYQAWITDPKTALRQRRK

ENSGT00390000013029_1_Linker_0_3 (1775, 2665)

EKKKSARGEQKRKRRGSGEGS--VDW
EDREEEPVKKKSDGPDNIIKRIFNIVKFTWVLFLATVDSFTTWLNSISREHIDISMVLRI
ERCMLTREIKKGN-VPTRESI-HMYYQNHI-MNLSRESGLDTIEAQPRAGPGAPPAHRMD
SLD---SHDSISSCYTEATTLFSRQSTLDDLDGPDPVPKTSERSRPRLRKMLSMDMSSSS
ADSGSLVSSEPTQCTTLYSRQGTTETIEEVEAEVEEETVGMQAEDQE-------------
-------------EEYGIEAAEAVGDEDEDELPQVSTDDGDVEAPPSYSKAVSFEHLSFG
SQD-GAGAKNHMVVSPDDSRTD-----KLESSLLPPLTHELTASELLLNKMFRDDE--LE
ESERFYVGQPRFLLLFYAMYNTLVARSEMVCYFVIILNHMVSASMITLLLPILIFLWAML
SVPRPSRRFWMMAIIYTEVAIVVKYFFQFGFFPWNKNVEI--YKDKPYHPPNIIGVEKKE
GYVLYDLIQLLALFFHRS--ILKCHGLWDEDEVVDSSTDKEDSDAEL---SLSHSRRDSA
---DSLKSINLAASVES-----------------VHVTFPEPPAAVHRKR--SSCSSPGS
PGSSFSSNRSKR-----GST-STRNSSQKG--GSILSVK-----QPSRRELY-MKKLQEH
LVQAKDF----------------TIRKTLQIYVPIKQFFYNLIHPDYSAVTDVYVLMFLA
DTVDFVIIVFGFWAFGK-HSAAADITSSLSEDQVPGPFLVMVLIQFGTMVVDRALYLRKT
VLGKVIFQVILVFGIHFWMFFILPGVTERKFSQNLVAQLWYFVKCVYFGLSAYQIRCGYP
TRVLGNFLTKSYNYVNLFLFQGFR

PF12166 // ENSGT00390000013029_1_Domain_3 (2665, 3094)

LVPFLTELRAVMDWVWTDTTLSLSSWICVEDIYAHI
FILKCWRESEKRYPQPRGQKKKKVVKYGMGGMITVLLICIVWFPLLFICVVLT-------
------ALCILAFQPIFTMSAQGSQLKVMEPQEFNKFWKK-----FSRDTVAMQFLENYE
REDITVAELEGNSNSLWTISPPSKQKMIQELMDPKNIFSIVFSWSIQRNMSLGAKAEIAT
EKLTFTLENNTRKSIAKMIAGNDTESSKTPVTIERMYPYYVKAPSDSNSKPIKQLLS--E
KDFMNITI-------------VLFRDNATNSNSEWWVLNLTGNRIYNRESQALELVVFND
KVSPPSLGFLAGYGIMGLYASVVLVIGKFVREFFSGISHSIMFEELPNVDRILKLCTDIF
LVRETGELELEEDLYAKLIFLYRSPETMIKWTREKTN

--------------------------------CAFRYNGLSFVYLIYLLLIPLFSEPTKA
T------MQGHTGRLLKSLCLLSLSFLLLHIVFHIT-----LASLEAQHRIAPGYNCSTW
EKTFRQIGFE---SLEGADAGNGIRVFVPDIGMFIVSLTIWLVCRNMVQKPAVEETARDT
PEFENEELARGEKMDSKEALIED-EDLDGADMEDTEGEDSARLRLFRQLASLASRLKEFV
GNMITTAGKVVVTILLGS-SGMMLPSLTSAVYFFVFLGLCTWWSWCRTFDPLLFSCLCVL
LAIFTAGHLIGLYLYQFQFFQEAVPPNDYYA-RLFGIKSVIQTDCSSTWKIIVNPDLSWY
HHANPILLLVMYYTLATLI-RIWLQEPL--VPDEMAK------DEDCALGDSPSQH-SAE
RRRSLWYAAHYPTDERKLLSMTQDDYKPSDGLLVTVNGNPVDYHTIHPSLPLENGPAKAD
LYSTPHYRWEPLEGSAEKKED-EEYEKEESEGERSREDKRSVKVHAMVSVFQFIMKQSYI
CALIAMM-AWSITYHSWLTFVLLIWSCTLWMIRSRRKYAMVSSPFMVIYANLLLVLQYIW
SFELP--EIKKVPGFLEKKEPGELAS---------KILFTITFWLLLRQHLTEQKALREK
EALLSEVKIGSQENEEK-----DEDLEEVQV---EGEPKEKEE-----------------
-----EEG---EGPKEEKQETKEEEEEAEEDGDDQDIMKVLGNLVVAMFIKYWIYVCGGM
FFFVSFEGKIVMYKIIYMVLFLFCVALYQVHYEWWRKILKYFWMSVVIYTMLVLIFIYTY
QFENFPSLWQNMTGLKKEKLEDLGLKQFTVAELFTRIFIPTSFLLVCILHLHYFHDRFLE
LTDLKAIPSKEDSTIYSHAKVNGRVYLIIN-----------RLAHPEGSLPDLAMMHLTP
SLDKPEVHKQAEPGQQHPEGQEQTEEGRKGEPSKDGKDSEEDSE-EDSEE-------EEE
LEEEEELKWHLVIDRLTVLFLKFLEFFHKLQVFVWWMLELHITKIVSSYIIWVSVKE--V
SLFNYVFLISWAFALPYAKLRRLASSVCTVWTCVIIVCKMLYQLQTIKPSTFSVNCTLPN
ENQTNIP-LKELNKSLLYSAP-IDPTEWVGLRKSSPLLVYLRNNLLMLAILAFEVTIYRH
QEYYRGRNKLTAPVSKTIFHDVTRLHLDDGLLSCAKYFTNYFFYKFGLETCFLLSVNVIG
QRMDFYAMIHACWLIGVLYRRRRKAIAEVWPKYCCFLACILTLQYLVCIGVPPAPCRDYP
WRLKGADFNDNIIKWLYFPDFIVRPNPVFLVYDFMLLLCASLQRQIFEDENKAAVRIMAG
DNVEICMNLDAASFSQHNPVPDFIHC-RSYLDMSKVVIFSYLFWFVLTIIFITGTTRISI
FCMGYLVACFYFLLFGGDLLLKPIRSILRYWDWLIAYNVFVITMKNILSIG

PF15917 // ENSGT00390000013029_1_Domain_0 (1492, 1774)

ACGYIGTLV
KNSCWLIQAFSLACTVKGYT--------MPSDDASCKLPSGEAGIIWDSICFAFLLLQRR
VFMSYYFLHVVA--------DIKASQILASRGAELFQATIVKAVKARIEEEKKSMDQLKR
QMDRIKARQQKYKKGKERMLSLTQESGEGQDTQKLSEEDDE-READKQKAKGKTKQWWRP
WVDHASMVRSGDYYLFETDSEEEEEEELKKEDEELPRKSAF-------------------
--------------QFVYQAWITDPKTALRQRR

ENSGT00390000013029_1_Linker_0_3 (1774, 2665)

TEKKKSAREEQKCKRRGSGEGL--VDW
EDREEEPVKKKSDGPDNIIKRIFNIVKFTWVLFLATVDSFTTWLNSISREHIDISTVLRI
ERCMLTREIKKGN-VPKRESI-HMYYQNHI-MNLSQESGLDTIEDRPGARPGAPPAHRMD
SLD---SHDSISSCYTEATMLFSRQSTLDDLDGPDPVPKTSERSRPRLRKMLSMDMSSSS
ADSGSLASSEPTQCTMLYSRQGTTETIEEVEAEAEEETVGAQLEEEEEEEEEEHG-----
-----------AKCGAEAEEASLSPEDEEDEPPLLSTNDGDMEVPPSYSKAVSFEHLSFG
SQD-GAEAKNHMVVSPDDSRTD-----KLESSLLPPLTHELTASELLLNKMFHDDE--LE
ESERFYVGQPRFLLLFYAMYNTLVARSEMVCYFVIILNHMVSASMITLLLPILIFLWAML
SVPRPSRRFWMMAIVYTEVAIVVKYFFQFGFFPWNKNVEI--HKDKPYHPPNIIGVEKKE
GYVLYDLIQLLALFFHRSRTLLTCHGLWDEEEAVDSGTDKADSDAEL---SLSRSRRDSA
---DSLKSIDLAASVES-----------------VQVTFPEPPRALRRKR--SSSSGRDS
PGSSFSSNRSKR-----GST-STRNSSQKG--SSILSVK-----QKSRRELY-VKKLQGH
LVRAKAF----------------TIRKTLQIYVPIRQFFYNLIHPDYSAVTDVYVLMFLA
DTVDFIIIVFGFWAFGK-HSAAADITSSLSEDQVPGPFLVMVLIQFGTMVVDRALYLRKT
VLGKVIFQVILVFGIHFWMFFILPGVTERKFSQNLVAQLWYFVKCVYFGLSAYQIRCGYP
TRVLGNFLTKSYNYVNLFLFQGFR

PF12166 // ENSGT00390000013029_1_Domain_3 (2665, 3094)

LVPFLTELRAVMDWVWTDTTLSLSSWICVEDIYAHI
FILKCWRESEKRYPQPRGQKKKKVVKYGMGGMIIVLLICIVWFPLLFMSLIKSVAGVINQ
PLDVSVTITLGGYQPIFTMSAQQSQLKVMDNQRF---------------GGAMQFLENYE
REDITVAELEGNSNSLWTISPPSKQKMIQELTDPNSSFSVVFSWSIQRNMSLGAKAEIAT
DKLTFPLKNVTRESIAKMIAGNDTESSKTPVTIEKIYPYYVKAPSDSNSKPIKQLLS--E
KDFMNITI-------------ILSRDNTIKSSSEWWVLNLTGDRVYDQESQALELMVFND
KVSPPSLGFLAGYGIMGLYASVVLVIGKFVREFFSGISHSIMFEELPNVDRILKLCTDIF
LVRETGELELEEDLYAKLIFLYRSPETMIKWTREKTN

------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------MLTPHLARLAHPEGSLPDLAAMNFTA
SLEKPEVKKLTELAEEKPEGCLEK-----GEPGKDSEESEVEED-------EEEESEEEE
ETSDLKNKWHLVIDRLTVLFLKFLEYFHNLQVFMWWILELHIIKIVSSYIIWVSVKE--V
SLFNYVFLISWAFALPYAKLRRLASSVCTVWTCVIIVCKMLYQLQTIKPENFSVNCSLPN
ENQTNIP-LQDLNKSLLYSAP-IDPTEWVGLRKSSPLLVYLRNNLLMLAILAFEVTIYRH
QEYYRGRNNLTAPVSKTIFHDITRLHLDDGLINCAKYFINYFFYKFGLETCFLMSVNVIG
QRMDFYAMIHACWLIAVLYRRRRKAIAEVWPKYCCFLACIITFQYFICIGIPPAPCRDYP
WRFKDANFNDNIIKWLYFPDFIVRPNPVFLVYDFMLLLCASLQRQIFEDENKAAVRIMAG
DNVEICMNLDAASFSQHNPVPDFIHC-RSYLDMSKVVIFSYLFWFVLTIIFITGTTRISI
FCMGYLVACFYFLLFGGDLLLKPIKSILRYWDWLIAYNVFVITMKNILSIGACGYIGTLV
KNSCWLIQAFSLACTVKGYK--------MPDDDSSCKLPSGEAGIIWDSICFAFLLLQRR
VFMSYYFLHVVA--------DIKASQILASRGAELFQATIVKAVKARIEEEKKSMDQLKR
QMDRIKARQQKYKKGKERMLSLTQESGEGQDIQKLSEEDDE-REAEKQKAKGKKKQWWRP
WVDHASMVRSGDYYLFETDSEEEEEEELKKEDEEPPRKSAF-------------------
--------------QFVYQAWITDPKTALRQRRKEKKRSAREDQKRRRKGSGDGA--VEW
EDREDEPVKKKSDGPDNIIKRIFNILKFTWVLFLATVDSFTTWLNSISREHIDISTVLRI
ERCMLTREIKKGN-VPTRESI-HMYYQNHI-MNLSRESGLDTIDQRPGAAAGAQPAHRMD
SLD---SHDSIS------------------------------------------------
--------SEPTQCTMLYSRQGTTETIEEVEAEQEEEVLGAAPQPGDAEEEEDEEEEEEG
VEEAEEEREEEEEFPVGAEDCSLTPE---EELPQFSTEDGDVEAPPSYSKAVSFEHLSFG
SQDD-SGAKNHMVVSPDDSRTD-----KLESSILPALTHELTASELLLNKMFHDDE--LE
ESEKFYVGQPRFLLLFYAMYNTLVARSEMVCYFVIILNHMVSASMITLLLPILIFLWAML
SVPRPSRRFWMMAIVYTEVAIVVKYFFQFGFFPWNKNVEL--NKDKPYHPPNIIGVEKKE
GYVLYDLIQLLALFFHRS--ILKCHGLWDEDDIVESGTDKDESDDEL---SLGHGRRGSC
---DSLKSINLAASVES-----------------VHVTFPEQQMAVRRKR--SGGSSQIS
PTSSFSSNRSRR-----GST-STRNSSQKG--S-VLSIK-----QKSKRELY-MEKLQEH
LIKAKAF----------------TIKKTLQIYVPIRQFFYDLIHPDYSAVTDVYVLMFLA
DTVDFIIIVFGFWAFGK-HSAAADITSSLSEDQVPGPFLVMVLIQFGTMVVDRALYLRKT
VLGKVIFQVILVFGIHFWMFFILPGVTERKFSQNLVAQLWYFVKCVYFGLSAYQIRCGYP
TRVLGNFLTKSYNYVNLFLFQGF

PF12166 // ENSGT00390000013029_1_Domain_3 (2664, 3095)

RLVPFLTELRAVMDWVWTDTTLSLSSWICVEDIYAHI
FILKCWRESEKRYPQPRGQKKKKVVKYGMGGMIIVLLICIVWFPLLFMSLIKSVAGVINQ
PLDVSVTITLGGYQPIFTMSAQQSQLKVMNKTTFDKFVKA-----FTKDTGAMQFLENYE
KEDITVAELEGNSNSLWTISPPSKRKMIQELMDLKSSFSVVFSWSIQRNMSLGAKAEIAT
DKLSFALENVTRENIAKMIAGNDTESSKTPVIIEKIYPYYVKAPSDSNSKPIKQLLS--E
NNFMNITI-------------ILYRDNATKSNSEWWVLNLTGNRIYEQQSQALELVVFND
KVSPPSLGFLAGYGIMGLYASVVLVIGKFVREFFSGISHSIMFEELPNVDRILKLCTDIF
LVRETGELELEEDLYAKLIFLYRSPETMIKWTREKTN

----------MASEVVCGLVFRLLLPICLAVACAFRYNGLSFVYLIYLLLIPLFSEPTKA
T------MQGHTGRLLQSLCITSLSFLLLHIIFHIT-----LASLEAQHRIAPAYNCSTW
EKTFRQIGFE---SLKGADAGNGIRVFVPDVGMFIASLTIWLVCRNIVKKPDTEEVAQFN
SDCENEELARGEKMDSEEALIYE-EDLDGEEGMEGELEESTKLKMFRRLASVASKLKEFI
GNMITTAGKVVVTILLGS-SGMMLPSLTSAVYFFVFLGLCTWWSWCRTFDPLLFGCLCVL
LAIFTAGHLIGLYLYQFQFFQEAVPPNDYYASRLFGIKSIIQTDCSSTWKIIVNPQLSWY
HHANPILLLVMYYTLATLI-RIWLQEPL--VQDEMAK------EEEGTLDCSANQN-TAE
RRRSLWYATQYPTDERKLLSMTQDDYKPSDGLLVTVNGNPVDYHTIHPSLPLENGPAKTD
LYTTPQYRWEPSEESSEKKEE-DEDRKEGSEGEGSQEEKRSVRIHAMVTVFQFIMKQSYI
CALIAMM-AWSITYHSWLTFVLLIWSCTLWMIRNRRKYAMISSPFMVVYANLLLVLQYIW
SFELT--EIKKVPGFLEKKKPGELAS---------KVNKAN-------------------
-----------DMVFC----LEDEELQDVQV---E-----------------------GQ
PPEKAE-EEEIKE---ERHEIKKEEEEEVEEDDDQDIMKVLGNLVVALFIKYWIYVCGGM
FFFVSFEGKIVMYKIIYMVLFLFCVALYQVHYEWWRKILKYFWMSVVIYTMLVLIFIYTY
QFENFPGLWQNMTGLKKEKLEDLGLKQFTVAELFTRIFIPTSFLLVCILHLHYFHDRFLE
LTDLKSIPSKEDNAIYSHAKVNGRVYLIIN-----------RLAHPEGSLPDLAVMNMTA
SLDKPEVQKLVEAGEERPEECAKKTE--KGEPGKDSDESEEEED-EE-------EESEEE
ETSDLRNKWLLVIDRLTVLFLKFLEYFHKLQVFMWWILELHIIKIVSSYIIWVTVKE--V
SLFNYVFLISWAFALPYAKLRRVASSVCTVWTCVIIVCKMLYQLQTIKPENFSVNCSLPN
ENQTNIP-LNELNKSLLYSAP-VDPTEWVGLRKSSPLLVYLRNNLLMLAILAFEVTIYRH
QEYYRGRNNLTAPVSKTIFHDITRLHLDDGLVNCAKYFINYFFYKFGLETCFLMSVNVIG
QRMDFYAMIHACWLIGVLYRRRRKAIAEVWPKYCCFLACIITFQYFVCIGIPPAPCRDYP
WRFKGANFNDNIIKWLYFPDFIVRPNPVFLVYDFMLLLCASLQRQIFEDENKAAVRIMAG
DNVEICMNLDAASFSQHNPVPDFIHC-RSYLDMSKVIIFSYLFWFVLTIIFITGTTRISI
FCMGYLVACFYFLLFGGDLLLKPIKSILRYWDWLIAYNVFVITMKNILSIG

PF15917 // ENSGT00390000013029_1_Domain_0 (1492, 1775)

ACGYISALV
RNSCWLIQAFSLACTVKGYK--------MPEDDSKCKLPSGEAGIIWDSICFAFLLLQRR
VFMSYYFLHVVA--------DIKASQILASRGAELFQATIVKAVKARIEEEKKSMDQLKR
QMDRIKARQQKYKKGKERMLSLTQESGEGQDIQKLSEEDDE-READKQKAKGKKKQWWRP
WVDHASMVRSGDYYLFETDSEEEEEEELKKEDEEPPRKSAF-------------------
--------------QFVYQAWITDPKTALRQRRK

ENSGT00390000013029_1_Linker_0_3 (1775, 2665)

EKKKLAKEEEKGRRKGSGEGS--LEW
NDREDGPVKKKSDGPDNIIKRIFNILKFTWVLFLATVDSFTTWLNSISREHIDISTVLRI
ERCMLTREIKKGN-VPTRESI-HVYYQNHI-MNLSRESGLDTIDEHPGAGSRAQAAHRMD
SLD---SHDSISSCYTEATLLISRQSTLDDLDGQDPVPKTSERARPRLRKMFSMDMSSSS
ADSGSVASSEPTQCTMLYSRQGTTETIEEVEAEAEEEVVEGLESDLHDAEDK--------
-----EYAAE---YEAGVEEVSLTPD---EELPQFSTDDGDVEAPPSYSKAVSFEHLSFA
SQDD-SGAKNHMVVSPDDSRTD-----KLESSILPPLTHELTASELLMNKMFHDDE--LE
ESERFYVDQPRFLLLFYAMYNTLVARSEMVCYFVIILNHMISASIITLLLPILIFLWAML
SVPRPSRRFWMMAIVYTEVAIVVKYFFQFGFFPWNKDLEF--NKDKPYFPPNIIGVEKKE
GYVLYDLIQLLALFFHRS--ILKCHGLWDEDDIVDSGTDKEESDDEL---SLDHDRRGSS
---DSLKSINLAASVES-----------------VHVTFPEQPGAIRRKR--SCSSSQIS
PRSSFSSNRSKR-----GST-STRNSSQRG--SSVLSIK-----QKSKRELY-MEKLQEH
LIKAKAF----------------TIKKTLQIYVPIRQFFYDLIHPDYSAVTDVYVLMFLA
DTVDFIIIVFGFWAFGK-HSAAADITSSLSEDQVPGPFLVMVLIQFGTMVVDRALYLRKT
VLGKVIFQVILVFGIHFWMFFILPSVTERKFSQNLVAQLWYFVKCVYFGLSAYQIRCGYP
TRVLGNFLTKSYNYVNLFLFQGFR

PF12166 // ENSGT00390000013029_1_Domain_3 (2665, 3094)

LVPFLTELRAVMDWVWTDTTLSLSSWICVEDIYAHI
FILKCWRESEKRYPQPRGQKKKKAVKYGMGGMIIVLLICIVWFPLLFMSLIKSVAGVINQ
PLDVSVTITLGGYQPIFTMSAQQSQLKVMDNTKYKAFVKS-----FTTNSGAMQFLENYE
KEDITVAELEGNSNSLWTISPPSKQKMIQELTDPNSCFSVVFSWSIQRNMTLGAKAEIAT
DKLSFPLANETRNNIAKMIAGNDTESSNTPVTIEKIYPYYVKAPSDSNSKPIKQLLS--E
SNFMNITI-------------ILFRDNVTKSNSEWWVLNLTGNRIYNQGSQALELVVFND
KVSPPSLGFLAGYGIMGLYASVVLVIGKFVREFFSGISHSIMFEELPNVDRILKLCTDIF
LVRETGELELEEDLYAKLIFLYRSPETMIKWTREKTN

----------MASEVVCGLVFRLLLPICLAVACAFRYNGLSFIYLIYLLLIPLFSEPTKA
T------MQGHTGRLLKSLCFMSFSFLLLHIIFHIT-----LASLEAQHSIAPGYNCSTW
EKTFRQIGFE---SLKGADAGNGIRVFVPDIGMFIASLTIWLICRNIVQKPDPVEAAQYN
SECENEELAGGEKMDSEEALIYE-EDLDVGEGADGEVEESTKLKMFRRLASIASKLKEFI
GNMITTAGKVVVTILLGS-SGMMLPSLTSAVYFIVFLGLCTWWSWCRTFDPLLFSCLCVL
LAIFTAGHLIGLYLYQFQFFQEAVPPNDYYA-RLFGIKSVIQTDCSSTWKIIVNPELSWY
HHANPILLLVMYYTLATLI-RIWLQEPL--VPEERLKE------EDGDLACSPNQN-TAE
RRRSLWYATHYPTDERKLLSMTQDDYKPSDGLLVTVNGNPVDYHTIHPSLPIENGPAKAD
LYSTPQYRWEPSEESSEKKED-EEDKKDESEEERSQEEKRSVRVHAMVSVFQFIMKQSYI
CALIAMM-AWSITYHSWLTFVLLIWSCTLWMIRNRRKYAMISSPFMVAYGNLLLVLQYIW
SFELP--EIKKVPGFLEKKEPGELAS---------KILFTITFWLLLRQHLTEQKALQEK
EALLSEVKIGSQEPEEK----EDEELQDVQVE---GEPREKEEEEEAEEAQPE-------
-------------------RKKEEEEEAMGEDDEQDIMKVLGNLVVALFIKYWIYVCGGM
FFFVSFEGKIVMYKIIYMVLFLFCVALYQVHYEWWRKILKYFWMSVVIYTMLVLIFIYTY
QFENFPGLWQNMTGLKKEKLEDLGLKQFTVAELFTRIFIPTSFLLVCILHLHYFHDRFLD
LTDLKSIPSKEDNTIYSHAKVNGRVYLIIN-----------RLAHPEGSLPDLAMMNLTT
SLDKPEVPKLVEPGEKSPGEFSDKAEK--ADL--GKDSEESEEEDDEE-----EESEEEE
EASDLRNKWHLVIDRLTVLFLKFLEYFHKLQVFMWWILELHIIKIVSSYIIWVTVKE--V
SLFNYVFLISWAFALPYAKLRRLASSVCTVWTCVIIVCKMLYQLQTIKPENFSVNCSLPN
ENQTNIP-LHELNKSMLYSAP-VDPTEWVGLRKSSPLLVYLRNNLLMLAILAFEVTIYRH
QEYYRGRNNLTAPVSKTIFHDITRLHLDDGLVNCAKYFINYFFYKFGLETCFLMSVNVIG
QRMDFYAMIHACWLIAVLYRRRRKAIAEVWPKYCCFLACIITFQYLICIGIPPAPCRDYP
WRFKGANFNDNIIKWLYFPDFIVRPNPVFLVYDFMLLLCASLQRQIFEDENKAAVRIMAG
DNVEICMNLDAASFSQHNPVPDFIHC-RSYLDMSKVIIFSYLFWFVLTIIFITGTTRISI
FCMGYLVACFYFLLFGGDLLLKPIKSILRYWDWLIAYNVFVITMKNILSIG

PF15917 // ENSGT00390000013029_1_Domain_0 (1492, 1775)

ACGYIETLV
ENSCWLIQAFSLACTVKGYTM--------PNENASCKLPSGEAGIIWDSICFAFLLLQRR
VFMSYYFLHVVA--------DIKASQILASRGAELFQATIVKAVKARIEEEKKSMDQLKR
QMDRIKARQQKYKKGKERMLSLTQESGEGQDIQKLSEEDDD-REAEKQKAKGKKKQWWRP
WVDHASMVRSGDYYLFETDSEEEEEEEPKKEDEEPPRKSAF-------------------
--------------QFVYQAWITDPKTALRQRRK

ENSGT00390000013029_1_Linker_0_3 (1775, 2665)

EKKKSAREEQKRRRKASGEGA--VEW
EDHDDEPIKKKSDGPDNIIKRIFNILKFTWVLFLATVDSFTTWLNSISREHIDISTVLRI
ERCMLTREIKKGN-VPTRESI-HMYYQNHI-MSLSRESGLDTIDEHPEDTARAQAARRMD
SLD---SHDSISSCYTEATLLISRQSTLDDLDGQDPVPKTSERARPRLRKMFSMDMSSSS
ADSGSLVSSEPTQCTMLYSRQGTTETIEEVEAEAEEEVMD-PEPELDDASE---------
-----EYTAEYE---AEAEEVGL--TP-EEELPQFSTDDGDVEAPPSYSKAVSFEHLSFG
-SQDDSGAKNHMVVSPDDSRTDKL---SPGSIILPPLTHELTASELLLNKMFHDDE--LE
ESEKFYVGQPRFLLLFYAMYNTLVARSEMVCYFVIILNHMISASMITLLLPILIFLWAML
SVPRPSRRFWMMAIVYTEVAIVVKYFFQFGFFPWNKNVEL--HKDKPYHPPNIIGVEKKE
GYVLYDLIQLLALFFHRS--ILKCHGLWDEDDIVDSDTDKDESDEEL---SLSRGRRGSS
---DSLKSINLAASVES-----------------VHVTFPEQPAAIRR--KRSNSGSQIS
RGSSFSSTRSKR-----GS-TSTRNSSQKG--SSILSVK-----QKSKRELY-MEKLQE-
--------------H-FIKAKAFTMKKTLQIYVPIKQFFYDLIHPDYSAVTDVYVLMFLA
DTVDFIIIVFGFWAFGK-HSAAADITSSLSEDQVPGPFLVMVLIQFGTMVVDRALYLRKT
VLGKVIFQVILVFGIHFWMFFILPSVTERKFSQNLVAQLWYFVKCVYFGLSAYQIRCGYP
TRVLGNFLTKSYNYVNLFLFQGFR

PF12166 // ENSGT00390000013029_1_Domain_3 (2665, 3094)

LVPFLTELRAVMDWVWTDTTLSLSSWICVEDIYAHI
FILKCWRESEKRYPQPRGQKKKKVVKYGMGGMIIVLLICIVWFPLLFMSLIKSVAGVINQ
PLDVSVTITLGGYQPIFTMSAQQSQLKVMDQSRFKKFMKS-----FSRDTTAMQFLENYE
KEDITVAELEGNSNSLWTISPPSKQKMIQELTDPNSSFSLVFSWSIQRNMSLGAKAEIAT
DKLSFTLQNPTRRNIAKMIAGNDTQSSNTPVTIERIYPYYVKAPSDSNSKPIKQLLS--E
NNFMNITI-------------ILSRDNLTKSNSEWWVLNLTGNRIYSQESQALELVVFND
KVSPPSLGFLAGYGIMGLYASVVLVIGKFVREFFSGISHSIMFEELPNVDRILKLCTDIF
LVRETGELELEEDLYAKLIFLYRSPETMIKWTREKTN

------------------------------------------------------------
-------MQGHTGRLLKSLCFISLSFLLLHIIFHIT-----LASLEAQHRIAPGYNCSTW
EKTFRQIGF---ESLRGADAGNGIRVFAPDIGMFIASLTIWLLCRDIVQKPVTDEAAQSN
LEFENEELAGGEKIDSEEALIYE-EDLDGGDGVEGELEESTKLKMFRRLACVASKLKEFI
GNMITTAGKVVVTILLGS-SGMMLPSLTSSVYFFVFLGLCTWWSWCRTFDPLLFSCLCVL
LAIFTAGHLIGLYLYQFQFFQEAVPPSDYYA-RLFGIKSVIQTDCSSTWKIIVNPDLSWY
HHANPILLLVMYYTLATLI-RIWLQEPL--VQEERTK------EEDKALACSPIQI-TAE
RRRSLWYATHCSTDERKLLSMTQDDYKPSDGLLVTVNGNPVDYHTIHPSLPMENGPGKAD
LYSTPQYRWEPSDESSEKREE-EEEEKEEFEEERSREEKRSIKVHAMVSVFQFIMKQSYI
CALIAMM-AWSITYHSWLTFVLLIWSCTLWMIRNRRKYAMISSPFMVVYGNLLLILQYIW
SFELP--EIKKVPGFLEKKEPGELAS---------KILFTITFWLLLRQHLTEQKALREK
EALLSEVKIGSQENEEK----EDEELQDIQV---EGEPKEK-------------------
-----EEEDEAKEEKQERKKVEEEE---VEEGDEQDIMKVLGNLVVAMFIKYWIYVCGGM
FFFVSFEGKIVMYKIIYMVLFLFCVALYQVHYEWWRKILKYFWMSVVIYTMLVLIFIYTY
QFENFPGLWQNMTGLKKEKLEDLGLKQFTVAELFTRIFIPTSFLLVCILHLHYFHDRFLE
LTDLKSIPSKEDNTIYSHAKVNGRV-----------YLIINRLAHPEGSLPDLTMMHLTA
NLEKPEVRKLAEPGEEKPEGYSEKAQ--KGDLGKDSEESEEDGE-EE-----EESEE-EE
ETSDLRNKWHLVIDRLTVLFLKFLEYFHKLQVFMWWILELHIIKIVSSYIIWVSVKE--V
SLFNYVFLISWAFALPYAKLRRLASSVCTVWTCVIIVCKMLYQLQTIKPENFSVNCSLPN
ENQTNIP-LNELNKSLLYSAP-VDPTEWVGLRKSSPLLVYLRNNLLMLAILAFEVTIYRH
QEYYRGRNNLTAPVSKTIFHDITRLHLDDGLINCAKYFINYFFYKFGLETCFLMSVNVIG
QRMDFYAMIHACWLIAVLYRRRRKAIAEIWPKYCCFLACIITFQYFICIGIPPAPCRDYP
WRFKGASFNDNIIKWLYFPDFIVRPNPVFLVYDFMLLLCASLQRQIFEDENKAAVRIMAG
DNVEICMNLDAASFSQHNPVPDFIHC-RSYLDMSKVIVFSYLFWFVLTIIFITGTTRISI
FCMGYLVACFYFLLFGGDLLLKPIKSILRYWDWLIAYNVFVITMKNILSIGACGYIGTLV
HNSCWLIQAFSLACTVKGYQ--------MPAANSPCTLPSGEAGIIWDSICFAFLLLQRR
VFMSYYFLHVVA--------DIKASQILASRGAELFQATIVKAVKARIEEEKKSMDQLKR
QMDRIKARQQKYKKGKERMLSLTQEPGEGQDMQKLSEEDDE-READKQKAKGKKKQWWRP
WVDHASMVRSGDYYLFETDSEEEEEEELKKEDEEPPRRSAF-------------------
--------------QFVYQAWITDPKTALRQRHKEKKRSAREERKRRQKGSKEGP--VEW
EDREDEPIKKKSDGPDNIIKRIFNILKFTWVLFLATVDSFTTWLNSISREHIDISTVLRI
ERCMLTREIKKGN-VPTRESI-HMYYQNHI-MNLSRESGLDTIDERPGAASGAQTAHRMD
SLD---SHDSISSCYTEATMLFSRQSTLDDLDGQE-IPKTSERARPRLRKMLSMDMSSSS
ADSGSLASSEPTQCTMLYSRQGTTETIEEVEAEQEEEAGSTVPEPREAKEYE--------
-------APGYDVGAMGAEEASLTPE---EELTQFSTLDGDVEAPPSYSKAVSFEHLSFG
SQDD-SAGKNHMAVSPDDSRTD-----KLGSSILPPLTHELTASELLLNKMFHDDE--LE
ESEKFYVGQPRFLLLFYAMYNTLVARSEMVCYFVIILNHMVSASMITLLLPILIFLWAML
SVPRPSRRFWMMAIVYTEVAIVVKYFFQFGFFPWNKNAEV--NKDKPYHPPNIIGVEKKE
GYVLYDLIQLLALFFHRS--ILKCHGLWDEDDMTESGMDKEESDDEL---SLGHGRRDSS
---DSLKSINLAASVES-----------------VHVTFPEQQTAVRRKR--SSSNSEPS
QRSSFSSNRSQR-----GST-STRNSSQKG--SSVLSIK-----QKSKRELY-MEKLQEH
LIKAKAF----------------TIKKTLQIYVPIRQFFYNLIHPDYSAVTDVYVLMFLA
DTVDFIIIVFGFWAFGK-HSAAADITSSLSEDQVPGPFLVMVLIQFGTMVVDRALYLRKT
VLGKVIFQVILVFGIHFWMFFILPGVTERKFSQNLVAQLWYFVKCVYFGLSAYQIRCGYP
TRVLGNFLTKSYNYVNLFLFQGF

PF12166 // ENSGT00390000013029_1_Domain_3 (2664, 3095)

RLVPFLTELRAVMDWVWTDTTLSLSSWICVEDIYAHI
FILKCWRESEKRYPQPRGQKKKKVVKYGMGGMIIVLLICIVWFPLLFMSLIKSVAGVINQ
PLDVSVTITLGGYQPIFTMSAQQSQLKVMDQQNFNKFIQA-----FSRDTGAMQFLENYE
KEDITVAELEGNSNSLWTISPPSKQKMIHELLDPNSSFSVVFSWSIQRNLSLGAKSEIAT
DKLSFPLKNITRKNIAKMIAGNSTESSKTPVTIEKIYPYYVKAPSDSNSKPIKQLLS--E
NNFMDITI-------------ILSRDNTTKFNSEWWVLNLTGNRIYNPNSQALELVVFND
KVSPPSLGFLAGYGIMGLYASVVLVIGKFVREFFSGISHSIMFEELPNVDRILKLCTDIF
LVRETGELELEEDLYAKLIFLYRSPETMIKWTREKTN

----------MASEVVCGLIFRLLLPICLAVACAFRYNGLSFVYLIYLLLIPLFSEPTKT
T------MQGHTGRLLKSLCFISLSFLLLHIIFHIT-----LVSLEAQHRIAPGYNCSTW
EK---TFRQIGFESLKGADAGNGIRVFVPDIGMFIASLTIWLLCRNIVQKPVTDEAAQSN
PEFENEELAGGEKIDSEEALIYE-EDFNGGDGVEGELEESTKLKMFRRLASVASKLKEFI
GNMITTAGKVVVTILLGS-SGMMLPSLTSSVYFFVFLGLCTWWSWCRTFDPLLFSCLCVL
LAIFTAGHLIGLYLYQFQFFQEAVPPNDYYA-RLFGIKSVIQTDCSSTWKIIVNPDLSWY
HHANPILLLVMYYTLATLI-RIWLQEPL--VQDEGTK------EEDKALACSPIQI-TAE
RRRSLWYATHYPTDERKLLSMTQDDYKPSDGLLVTVNGNPVDYHTIHPSLPMENGPGKAD
LYSTPQYRWEPSDESSEKREE-EEEEKEEFEEERSREEKRSIKVHAMVSVFQFIMKQSYI
CALIAMM-AWSITYHSWLTFVLLIWSCTLWMIRNRRKYAMISSPFMVVYGNLLLILQYIW
SFELP--EIKKVPGFLEKKEPGELAS---------KILFTITFWLLLRQHLTEQKALQEK
EALLSEVKIGSQENEEK-----DEELQDIQV---EGDPKEE-------------------
-----EE-EEAKEEKQERKKVEQEE---AEEEDEQDIMKVLGNLVVAMFIKYWIYVCGGM
FFFVSFEGKIVMYKIIYMVLFLFCVALYQVHYEWWRKILKYFWMSVVIYTMLVLIFIYTY
QFENFPGLWQNMTGLKKEKLEDLGLKQFTVAELFTRIFIPTSFLLVCILHLHYFHDRFLE
LTDLKSIPSKEDNTIYSHAKVNGRVYLIINSIKKKLPIHQNELAHPEGSLPDLTMMHLTA
SLEKPEVRKLAEPGEEKPEGYSEKAQ--KGDLGKDSEESEEDGE-EE-----EESEE-EE
ETSDLRNKWHLVIDRLTVLFLKFLEYFHKLQVFVWWILELHIIKIVSSYIIWVSVKE--V
SLFNYVFLISWAFALPYAKLRRLASSVCTVWTCVIIVCKMLYQLQTIKPENFSVNCSLPN
ENQTNIP-FNELNKSLLYSAP-IDPTEWVGLRKSSPLLVYLRNNLLMLAILAFEVTIYRH
QEYYRGRNNLTAPVSRTIFHDITRLHLDDGLINCAKYFINYFFYKFGLETCFLMSVNVIG
QRMDFYAMIHACWLIAVLYRRRRKAIAEIWPKYCCFLACIITFQYFICIGIPPAPCRDYP
WRFKGASFNDNIIKWLYFPDFIVRPNPVFLVYDFMLLLCASLQRQIFEDENKAAVRIMAG
DNVEICMNLDAASFSQHNPVPDFIHC-RSYLDMSKVIVFSYLFWFVLTIIFITGTTRISI
FCMGYLVACFYFLLFGGDLLLKPIKSILRYWDWLIAYNVFVITMKNILSIG

PF15917 // ENSGT00390000013029_1_Domain_0 (1492, 1775)

ACGYIGTLV
HNSCWLIQAFSLACTVKGYQ--------MPAANSPCTLPSGEAGIIWDSICFAFLLLQRR
VFMSYYFLHVVA--------DIKASQILASRGAELFQATIVKAVKARIEEEKKSMDQLKR
QMDRIKARQQKYKKGKERMLSLTQEPGEGQDMQKLSEEDDE-READKQKAKGKKKQWWRP
WVDHASMVRSGDYYLFETDSEEEEEEELKKEDEEPPRRSAF-------------------
--------------QFVYQAWITDPKTALRQRHK

ENSGT00390000013029_1_Linker_0_3 (1775, 2665)

EKKRSAREERKRRRKGSKEGP--VEW
EEREDEPIKKKSDGPDNIIKRIFNILKFTWVLFLATVDSFTTWLNSISREHIDISTVLRI
ERCMLTREIKKGN-VPTRESI-HMYYQNHI-MNLSRESGLDTIDEHPRAASGAQTAHRMD
SLD---SHDSIS------------------------------------------------
--------SEPTQCTMLYSRQGTTETIEEVEAEQEEEAGSMAPEPREAKEYE--------
-------ATGYDVGAMGAEEASLTPE---EELTQFSTLEGDVEAPPSYSKAVSFEHLSFG
SQDD-SAGKNHMAVSPDDSRTD-----KLGSSILPPLTHELTASELLLKKMFHDNE--LE
ESEKFYVGQPRFLLLFYAMYNTLVARSEMVCYFVIILNHMVSASMITLLLPILIFLWAML
SVPRPSRRFWMMAIVYTEVAIVVKYFFQFGFFPWNKNVEV--NKDKPYHPPNIIGVEKKE
GYVLYDLIQLLALFFHRS--ILKCHGLWDEDDMTESGMDKEESDDEL---SLGHGRRDSS
---DSLKSINLAASVES-----------------VHVTFPEQQTAVRRKR--SGSSSEPS
QRSSFSSNRSQR-----GST-STRNSSQKG--SSVLSTK-----QKSKRELY-MEKLQEH
LIKAKAF----------------TIKKTLEIYVPIKQFFYNLIHPEYSAVTDVYVLMFLA
DTVDFIIIVFGFWAFGK-HSAAADITSSLSEDQVPGPFLVMVLIQFGTMVVDRALYLRKT
VLGKVIFQVILVFGIHFWMFFILPGVTERKFSQNLVAQLWYFVKCVYFGLSAYQIRCGYP
TRVLGNFLTKSYNYVNLFLFQGFR

PF12166 // ENSGT00390000013029_1_Domain_3 (2665, 3094)

LVPFLTELRAVMDWVWTDTTLSLSSWICVEDIYAHI
FILKCWRESEKRYPQPRGQKKKKVVKYGMGGMIIVLLICIVWFPLLFMSLIKSVAGVINQ
PLDVSVTITLGGYQPIFTMSAQQSQLKVMDQQSFNKFIQA-----FSRDTGAMQFLENYE
KEDITVAELEGNSNSLWTISPPSKQKMIHELLDPNSSFSVVFSWSIQRNLSLGAKSEIAT
DKLSFPLKNITRKNIAKMIAGNSTESSKTPVTIEKIYPYYVKAPSDSNSKPIKQLLS--E
NNFMDITI-------------ILSRDNTTKYNSEWWVLNLTGNRIYNPNSQALELVVFND
KVSPPSLGFLAGYGIMGLYASVVLVIGKFVREFFSGISHSIMFEELPNVDRILKLCTDIF
LVRETGELELEEDLYAKLIFLYRSPETMIKWTREKTN