ENSGT00390000012762_0 : Linker Region Query Results

MFRRARLSVKPNVRPGVGTR---G------SAAPNPQRGPEAPRPPEP--ATGSAPKPAE
PTD--VP--AVDSGGAEPQEQAPGSSNN--EKTGDGSN-VEESSTLPSAASQRRKRVSGT
SSLGQPPVSAPSQSRPL-------------------------------------------
--------------------------------------------------STVN-HDAPQ
PNPTPAKEKQPCSDRYRIYKARKLREMLKEELRKEK--KQWKNKFATNESQRPPDRSKMT
MRDFIYY-LPDSNPMTSSVEQEKKCEKSLAPTPTRDRQENQSTQDANDNE----DVEEEV
DDGPLLVPRVKVAEDGSIILDEESLTVEVLRTKGPCVVEENDPIFERGST--TTYSSFRK
NYY-SKPWSNKETDMFFLAISMVGTDFSMIGQLFPHRARIEIKNKFKREEKTNGWRIDKA
FQEKRPFDFDFFAHLLQKVLAEEEKRKQKSTKCQNVKEKAP-KPRKNA-KAKTVNREEVN
DDPDE----SVNSDTADPERPQKDARTVREEQ--LPSSSAQHLHLAVLEQEQEQEQSQD-
KRRRNQGKANKREATTVLESVLDHSSPPAAEIHKS-T-------CPSEENENECNKEQTP
SFTQNTEDIAGL------ASCEETLMR---------MDPSPSTCNHQD------------
--IMPLASESSEPCAADLPVSEPGGAVSGDVNNAEPGGAVSGDVNNA-ESGCAGAGSADL
KTKSPETEQTDSVKPKSRSRLQRPKPNLSRPVGKKSVVSQDRQDGSNKDS--PSETAATK
NHMEKERVTESENFVTENTER-ESPSA-GTVSDLSEKS------SAQEDSQTKV------
--LRPTRLMRSRMQRPKPNVVKAAERKQILTSQEKVGSHVEKIE---------DDSCVVV
PPQMGNESHKNLQCEGA-A----SEPEQKD---PV-ESLQSEQPRALSECPSIQEDNKG-
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------NKLKQAPIVRTRFQKPKPNTGRRRR-RRRSSKE-----GIPVDMPVSGDL--
---TATREEI----------PRP-DTSPREEVPSVPLAPLTATASTMELESG--------
-VKDSSRNDTASNV--KMPEMADVTMEIDTGLETTGR-DTCPGEME-AEMIDIPMETEAS
L-KASLNETPP-------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------M---
-EKMPELIDNTGEICTNLGETARKEIFLQENGSKEVS-PVSEPETGLQETGKK-------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------LAVKESTSDM
--MDGTEEREADSEETE-----------------RQE---------------------IS
APVKE--AEEAKARGEVDSPLE----EIGGET--SQQA----IAAGAPVEQSASEEDLGD
SAGVE---EVEVE-STVGGKELKLKDAGEGH-VSLMVVVSGEKTAIEETIGHLKEKERES
SV---PW---ERRSGEIDVGEE---MVADL-EKTEKVDVSP-RDS-----EPEE----QT
SGQ-PEAEVIPSRSD-G-----STGPPQDRE-------------------------NISN
KI-S-VIPTLLEEKETTDKEVSSH---GESSSQNSGH--HVADQGTQLLDV----QE-QF
SDT---------------------------------------------------------
-----------------------------------------------------------N
LSKPLP-----------------QEQKPLQVKPAPFLRSRFKKPKPNLSRAALKRATLEA
EHCVPGK---------KP------------------------------------------
---------EAYKMETVVLQQDRDQAASFSS-PHNVPS--------LMASRENEKSGHEE
EEEAVVLPCTQIEKDPSP--PNSCEPKEDSQLTQNQ--EDSLVSPIGTPT-VNMVPQETK
PNVVQTTLPVRGRLQRPRPNVQKARQRQTV---EKGKAEG--ITK-N-------------
-----------EGPELQKDEAKTC-LTVAN-----SSGVESEVAVEVSSRVSEFKVNES-
--------------Q-G-----HVVPV--ENLSINKTSVLREQIR-HENKPYVPSPALLI
RRRFQKAKPNLGGARHKD-EQPGVEKGPTSE--NTALTTEDH-LLQKGDCDT--QLSVQA
RE---KTEMPLEVSMRKDC-VHSEESG----------SDRNDAQLKAGPSGGAREEIA-Q
EPTFSSSLEEQ--------------------------------------SLSKQI--S--
-----RPQLLKESSYSK-----------------TVPPRRTTVPSAS----ECEIDHSG-
KRAHRKM-K---ASVTKARGSKRIRGKTAKKEPRASK---SVLVTLRASQKDDE--DDAE
DFESDYEEETCHLAPEELN---KAPVFVPVGLRSPEPVSAQIEETMEE------------
-----------------------LEITMDGADLGCLTVVDHQLS-HVDIAARDEQPEKAV
YPSSFEVVIGEQPQEE-PGPGDGSTEAAITLLTMGDIVLQSEIIPGQGD-VGVCVFPDDH
SKDKNHVPFIPDNVNQKTVHDYQEV-CSPV-ISMSHVSFEDNKIVLE--EQSIREAAV-L
GEAMEEPLSTRDTACTM-S-TPLRMESMLVTPKAGSERILEISEPDGHQEVASLCMTKGT
EVEIQRE-TEENDSTA-----------------VELDDKSLEPVPAAETKEQEQL-LCVH
GVEGARVS-QEAILPARTEEHEDDLQGLQTLGAA--VASSEI-------------GQHTL
ESGQSLGDSVAEEALRESPEGSVVPMLHVPE----S-VPSN-IPEAQHEN-IS-P----Q
DDTVNLFANVQQD-GEDEQAFILTLVEIPTNTTEGFTDASM--HLMPSSLLPAPILVRSG
NAVE-RVDLSGS---LQASSVVQDVTCSSP----------SRSGDSEKPPAIVELTSRKR
FCCSPDESIH--VPPAKKSSI-------APGIDYQNCTSGVCSEELNV-FEKTEESCM-G
QG-------IFPTSESTH-ATSKPQKEHSEQT-SQN---TGSSGSL-GEIKDACVENTMT
ELPQSEVVSDKE----EKTDPASNSKQRDSVTSSSKPPLTRPGRRPLGFLSLICPKNS-L
ESDEVTQTHSKKRLKPHIPVSRRNLKKPNPLHASQKKN--QESSDPLPPPSVTETVS-DN
TGSSESSAAEVS-SDQPLVEEEKCKNGPKGASE-EEVTTVSEFVFSDIFIEVDETE----
-----

MFRRARLSVKPNVRPSVGAR------GSTA---PNPQRGQESPRPPEP--ATDSASKPAE
P----TDVPAVDFGGAEPQEKAPRS-S--SEKTGSDND-VEESSRSSPTVSQRRKRISST
SSLVKASVSVPSESHPLS------------------------------------------
---------------------------------------------------TVN-QEAAQ
PTTTPTKEKQPCSDRYRIYKAQKLREMLKEELRKEK--KQWKNKYAVNESQRPPDRSKMT
MRDFIYY-LPDNNPMTSSLEQEKKTEKPSTPVQTREQ-EGKSTANAEDN-----EMEEET
DDGPLLVPRVKVAEDGSIILDEESLTVEVLRTKGPCVVEENDPIFERGST--TTYSSFRK
NYY-SKPWSNKETDMFFLAISMVGTDFSMIGQLFPHRARIEIKNKFKREEKTNGWRIDKA
FQEKRPFDFDFFAHLLQKVLAEEEKRKQKSVKNHSLKEKKSTKPRKNV-KVKKVACEGVN
DDPDE----SMSSRISDTERSQKDAQTVDEE---SLTLSGKDAEQVALEVDLNQEKRR--
--RKKQDGANELEVNNLLENATVQAGPSKGEK-HKNKCQAIR----PEVKEGECSKEQML
SCTQNVDGIVGF------ASSEKVEK---------RTDPILSLSNQQDAT----------
--S-VAT-ESSESSTSDLPSLEVGIRALC-------------EVNDA-ESSCTEERNVDL
KNNSLEIDQTENVQPMLRGRFQRPKPNLSRA-GKKSVLSQGKTEAESKN--SHSKTSVEK
DHLEKDKMNTLDTLRMETRER-EN-PEAETVSM------LGEKNCLQEGSQLKA------
--LTSAKV-RGRFQKPKPNVGKAAGRKEILMSQEEIGANVEKNENESCADRD-------T
PQHMEDQSCKDFEEEDVIL-----QPEKND----SFQNVQPDEPKVLNECLSIQENNKA-
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------NKLNQVPILRTRFQKPKPNIGRGTGRREISSKE-----EVLEKILVSGEM--
---TAALRET----------VRP-DTSPKEMVPAEI-------STTKEMQSD--------
-LKETGRRAISPRE--KILDVIDVTREMETGLKARRR-EICLRERT-PEVIDATKEIDKD
LGETGRREIPPHENDPEEVKPVGEMETNLKATGN-ESSPREKTP----------------
----------------------------------------EVIDATQEIDKDLEDAGRRK
ISPKENGPEEVKPVD-----------------------------EMETDLKATGR-ESSP
REKTPEVIDTTEEIEIDLEETER-EISPQENGPEEVK-PLGEMETDLKAAGR--------
---------------------ESSPREKTPEVIDATEEI---------------------
-------EIDLKETEREISPQENGLEEVKPVGEMETDLKAT-GREISPRE--KTPEMIDA
TEKIDKDLEETGRREISPEENGPEEVKPVDEMETDL--------KATERESFPREKTPEV
--IDAAEKIEIDVEETK-R--------------------------------------EIA
PQENG--PEEVRPVGKMETDLKEIREEI------SQRE----------------------
--------KVLAEISAIREKEIDLKETGKRDI-SMMEKVSGKMAVIEEMETDMKETGRE-
NF---R----ERGSEEICVTEE---KVAEL-KKTGKTDISP-REN-----ELEE---TST
SRQ-TETHLMQSGSNDC-----SAMPSLDIK-------------------------NISS
EVLSMM-HTPVEEKRDSEKEVSSHFSRFRISSQTH-ESGKTEVLGIRSPDV----PE-PF
SDI---------------------------------------------------------
-----------------------------------------------------------N
LSRSLPQEQ-----------------KSLEIKPAPFVRSRFKRPKPNLARAALKRETTES
EKNIYEK---------KS------------------------------------------
---------ETKKMETIVMQENNEQADTLPSQHD-EAS--------LMITREKDTSG-HR
NEEAVILPCTQTEKNLSS--SNSCEPKEESQSAQAQ--ENDLVVSMGTNN-INTFQQEVK
ESVIQTARPVRGRLQRPRPNVRKTGQRQIV---DKDDAK--GIIK-E-------------
-----------ERTVLRKDETEKK-ILTAS-----NPQIETEIE-VPSSIVSEHRMC---
------------ENQ-S-----QVVLV--ENLHINKT---DETIRHE-NKLYVPSSAQMT
RRKFQKAKPNLRRAPSKK-EEPVLEKGTTDQ--SKEGKPEDH-LLQKGASNT--QLLLKE
KA---ELLTSMEVSARKDC-VGSNESALAKIDAELEEAGPSRRVGE----E-----TV-G
DNSLSSVVEEQ--------------------------------------YLNKL---TS-
-----CPQPLKESNYSK-----------------IALDGKTTISSAS----EYERNRSE-
RRSHR-KIK---PNVTRGRGSKRVRGKTSKKEPRASK---AMLVTLRASQEEE---DDAD
DFESDYEEESCHLAPEEVN---KAPVFVPVGLRSPEPVSAQIEETMEE------------
-----------------------LEITVNVPDVGCIAVVEHELP-NTDVTIEEMKQEENL
NASSFEMTTGEHIQDE-PGTNDGSTEAAITLLTMGDLVLQSEISTEQGD-VGVCILPHVH
SKDKSHIPFSLDNVNHKIVHECQEL-SSPV-ITTSPASFEEDKIVLE--EQSSREEISLM
EKVKENATPTRNTISKV--TSNLRIRSRLAKPKPNLEKTLGTNRFDDYREVSSLCVTKGE
EMETQRE-TEKNASKA-----------------TELEDKNLGPVTTAENKDQ-SKLACVH
GIKGTSIS-PEVNLSERNENQEESSQEVHMLSVAPVASS-ET-------------GPCTL
GLDRGLGENSVEEAQIKDPKGDSVLTLPVPE-----YTPTS-IPEVQQ-ENIINP----Q
DLTVNLVANVPQD-GEDEQAFILTLVEIPTNAVEEFTDATA--QFMPNPLLPAPILVKSV
NTEE-RGDMSIC---LPATSVGQDAVGLSIS---------GRDNS-KKPPDNLDLISRKR
FQCRLDENDH--ILPAKKCLL-------TLRDDCQEYTSEVHSKELTNAFEE-TGESHKG
Q-------NVFPTSGSTL-TTPEPQRQQVEPA-FQS---RGSR-SP-DA----CIDKNVP
QLPQDEM---IVSDKEERTDAAPKSEQVDSRTSSSKAPLSRPGRRPLGFLSLICSKNS-L
ESDEPMQVHSKKRLKPLIPALRQKLKRSNPFNESQKKN--QDSSDPLPSPSVINTQ----
SKNISSSATQVS--CDQPLLKEGHKSAQKRALQ-GEPTTVSEYFFNDIFIEVDETE----
-----

MFRRARLXXXXXXXXXXXXX------XXXXX---XXXXXXXXXXXXXX--XXXXXXXXAE
S----TDVPPVDCGA-ELREKTPKS-S--DEKTDGGKD-VEESSKSSSTVSQRRKRVSST
FSLVKPSVSVPSEPHPLS------------------------------------------
---------------------------------------------------TVN-QEAPQ
PNPVPTKEKQPCSDRYRIYKAQKLREMLKEELRKEK--KQWKNKYAVNESQRPPDRSKMT
MRDFIYY-LPNNNPMTSSLEQEKKTEKSLTPVQTREQ-EGKSTPDGEDNE----EIEEEM
DDGPLLVPRVKVAEDGSIILDEESLTVEVLRTKGPCVVEENDPIFERGST--TTYSSFRK
NYY-SKPWSNKETDMFFLAISMVGTDFSMIGQLFPHRARIEIKNKFKREEKTNGWRIDKA
FQEKRPFDFDFFAHLLQKVLAEEEKRKQKSVKNQTLKEKKSSKSQKNV-KVKKVSSERVN
DNPDE----SVSTRISDTEGSQKDAQTVEEEEQ-SLTLSGQDSEQNALEQDINQRKG---
--EKNQDESSEQEV-NLSGNATVQPGSSKGEN-HKNKCLSLS----PEINEDESHKEQKL
PCVQNTDDIVDL------SSNEKAEK---------RTDPALSPSSQQDAV----------
--S-VAT-ETSESSTSYLPSSEGGIRALC-------------EVNNA-ESSCTEEGNVDL
KDKALETDQTESIKPKTRGRLQRPKPNLSRAVGKKSVLSQGKTDAENKSL--HTETSVEK
NHMEKDKMNTLGISAMENKEK-EN-PEADTASN------LSEKICLQEDDQLKA------
--FRPARLMRGLLQRPKPNVGKAAERKETVTSQEKIGASVEKNENESCIDRD-------T
PEQIEDQAFKNFDCEDITS-----QSEKKD---TSFQNVQPDEPKVLNECLSIQEDNKA-
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------NKQVQILKTRFQKPKPNIRRRTGRREIFSKE----EEVPKEVLASEEM--
---TTALRET----------ARL-ETSPREKVPVET-------NTAKEMESD--------
-LKETERKDISPRE--KIPEMIDVTVEMETDLRETGR-----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------EIFPRE--KITKVTDA
TEERETDLEETERREISLQENAPEEVDTIGEVKTGL--------KETGREISPREKIPEM
--IDAAEEVETDLEETERR--------------------------------------EIP
TQEKA--SELKTIDDEMETDLNKIGIEI------SPRE----------------------
--------KVLVGISATGEREIDLEETGKRDI-SLMEKVSGKMTAIEET-----------
EF---R----KSRSEEISASEE---KVADL-EKTGKIDISL-REN-----EPEE---TGT
SRQ-TETDSLQRGSSDC-----SAVPSLNIK-------------------------DISS
EVQSVV-DVSVEEKRNSEKEISSQLSHLNISSQTS-ELDKIEDQRMRSPDV----PE-QF
SDI---------------------------------------------------------
-----------------------------------------------------------N
LSKSLPQEQ-----------------KPFEVKPAPFVRSRFKRPKPNLARAASKRETIEA
EKHAPGK---------KV------------------------------------------
---------EADKKGTVVIQQNGEQMRTLPSQRD-VAS--------LMASTEKDKSD-HS
QEEAVILPYVQTEKDLSP--SSSCEPIEETQSTQAQ--EKELVVSMGTYH-TNTCEQEMK
ESAIQTAPPVRGRLQRPSPNLRKVGQRQVI---EKNEAK--ETIK-E-------------
-----------ERTLQK--DETKK-FLTVP-----NSQIAMEIE-VVSSKVSEGRMY---
------------ENQ-------SHVLL--ENLHVNKINVSDEKTRHE-HKTYVSSPPQMI
RSQFQKAKPNLGRAQGKK-EESGIGTDRADQ--SKARKPEDN-LLQHGDSDT--QLLPKG
KA---EFLTSLEISARKGS-VGSKEIGLAKKDAQS-EVGPSGSVGE----K-----TV-G
NNSVCSVVEEQ--------------------------------------YVSKP---AS-
-----SPQLLKESNYSK-----------------IAVDRRTALSSAS----ECKIDRSE-
RRMRR-KIK---PNVPKGRGSKRIRSKTSKKEPRASK---PVLVTLRASQEEDE--DDAE
DFESDYEEESYHLAPEEVN---KAPVFVPVGLRSPEPVSAQIEETMEE------------
-----------------------LEIPMNIPDVGCIPVVEHQLSSNIDLTTEEMKQEENL
NALSVEMTTGEHSQAE-TGTSDGSTEAAITLLTMGGLVLQSEISTEQSD-VGVCVLPDVH
SSDKSHIPFCPDNTNLKIVHECQEP-SSPI-RSASLS-VEENKIILD--EQSTKEEIGLM
EEVKENSISSR-TTSEV--TNNLRMRSRFAKPKPNLKKILGTSRFGAHREVPSLFVTKE-
-VEIQRE-TEKNASKG-----------------RELEDKNLESVTTAESKEQ-SKLASVH
GIEETSIS-QEARLTGRDEDEEGRSAEVQLSSVAPVVSS-ES-------------RPHTL
DLGVGLGESSVEEALGKDSNGDSVLILHVPE----CS-----IPEVQQENINN-P----Q
DLTVNLVANVHQE-GEDEQAFILTLVEIPTNAVEEFADTTM--QLMPNPLLPAPILVKSV
NTEE-RGDMSIS---FPVTSAGQDDMCLSNS---------GRDDS-EKPPVNLDLVSRKR
FHCRLDESDH--VPPAKKSSL-------TLRDDCQKYTSEVCSKELLNVLEK-TGESYKG
Q-------GIFPTSGNTH-TIPEPQKEQLEPT-FQS---IRSK-PL-DKYT----EKNTS
QLPQDEI---GVSDKEKRTCAASKSEQMDSITSSSKTPLSRPGRRPLGFLSLICSKNS-L
ESDEPTQVRSKKRLKPLIPVSRQNLKRSNPLNTSQKKT--QESSD-LPSPSVVVNTQ---
PKNIDSSATQVS--CNHPLPKGECKDVQNRLPE-EEPMTVSEYFFSDIFIEVDETE----
-----

MFRRARLSVKPNVRPGVGTR------GSTA---SNPQRGRESPRPPEP--ATDSASKPAE
P----TDVPTVDFGGAEPQEKTPRS-S--TEKTGGDND-VEESSRSSSTVSQRRKRISST
SSLVKSSVSVPSESHPLP------------------------------------------
---------------------------------------------------TIN-QEAPQ
PTATSTKEKQPCSDRYRIYKAQKLREMLKEELRKEK--KQWKNKYAINESQRPPDRSKMT
MRDFIYY-LPDNNPMTSSLEQEKKTEKPSTPVQTREQ-EGKSTPNAEDN-----EMEEET
DDGPLLVPRVKVAEDGSIILDEESLTVEVLRTKGPCVVEENDPIFERGST--TTYSSFRK
NYY-SKPWSNKETDMFFLAISMVGTDFSMIGQLFPHRARIEIKNKFKREEKTNGWRIDKA
FQEKRPFDFDFFAHLLQKVLAEEEKRKQKSVKNQSLKEKKSTKPRKNV-KVKKVACEAVN
NDPDE----SMSSRISDTERSQKDAQTVEEE---SLTLSREDAEQVALEVDLNQKKRR--
--RKKQDGANELGVNNLLENATVQAGPSRGEK-HKNKCQAIR----PELKEGECSKEQML
SCTQNIDGIVGF------ASTEKVEK---------RTDPILSLSNQQDAT----------
--S-VAT-ESSESSTSDLPSFEVGIRALC-------------EVNNA-EGSCIEERNVDL
KNNSLEIDQTENVKPMLRGRFQRPKPNLSRA-GKKSVLSQGKTESESKN--SHSKTSVEK
NHVEKDKMNTLDILRMETAER-EN-PEAETVSV------LGEKNCLQEGSQLKA------
--LRPAQV-RGRLQKPKPNAGKAAERKEILISQEEIGANVEKNENESCADRD-------T
PQHMEDQSRKDFEEEDVIL-----QPEKND----SFQNVQPDEPKVLNECLSVQENNKA-
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------NKLNQVPILRTRFQKPKPNIGRGTGRREISSKE-----EVLEKILVSGEM--
---VAALRET----------VRL-DTSPKEMVPAEI-------NT-KEMQSD--------
-LKETGRRAISPRE--KILDVIDVTMEMETGLKAMGR-EICLREKT-PEVVDATEEIDKD
LEEAGRREISPQKNGPEEVKPLGEMETDLKATGN-ESSPREKTP----------------
----------------------------------------EMTDATEEIDKNLEETGRRK
ISPRENGPEEVKPVD-----------------------------EMETDLNATGR-ESSP
REKTPEVIDATEEI--DLEETER-EVSPQENGLEEVK-PLGEMETDLKATGR--------
---------------------ESSPRGKTPEVIDAIEEI---------------------
-------EIDLEETEREISPQENGLEEVKPLGEMQTDLKAT-GREISPRE--KTPEVIDA
TEEIDKDLEETGRREISPEENGPEGVKPVDEMETDL--------KATGRESSPREKTREV
--IDAAEVIETDLEETE-R--------------------------------------EIS
PQENG--PEEVKPVGKMETDLKEIREEI------SQRE----------------------
--------KVLAEISAIREKEIDLKETGKRDI-PMMEKVSGKMAVVEEMEADLKETGKE-
NF---R----ERGSEEICVTEE---KVAEL-KQTGKTDISP-REN-----ELEE---TST
SRQ-TDTHLMQSGSNDC-----SAMPSLDIQ-------------------------NISS
EVLSMM-HTPVEEKRNSEKEVSSHFSHFKISSQTH-ESDKTEVQGIQSPDV----PE-QF
SDI---------------------------------------------------------
-----------------------------------------------------------N
LSKSLPQEQ-----------------KPLEIKPAPFVRSRFKRPKPNLARAALKRETTES
EKYIYEK---------KS------------------------------------------
---------ETKKMETIVMQENNEQTETLPSQHD-EAS--------LMISREKDTSG-HR
NEEAVILPCTQTERNLSP--SNSCEPKEESQSAPVQ--KNDSVVSVGTNN-INTFQQEMK
ESVIQTARQVKGRLQRPRPNIRKTGQRQIV---DKGEAK--GIIK-E-------------
-----------GRTILSKDETEKK-VLTVS-----DSQIETEIE-VPSSAVPEHRMY---
------------ENQ-S-----QVVLV--ENLHVNKT---NETIRHE-NKPYVPSSAQMT
RRKFQKAKPNLGRAHSKK-EEPVLEKGTTDQ--SKEGKPEDH-LLQKGASNT--QLLLKE
KA---ELLTSLEVSARKDC-VGSKESALAKIDAELEEVGPSRRVGE----E-----TV-G
DNSPSSVVEEQ--------------------------------------YLNEL---AS-
-----CPQPLKETSYSK-----------------IALDGKTTISSTS----EYERNRGE-
RRSHK-KIK---PNVTRGRGSKRVRGKTPKKEPRASK---AMLVTLRASQEEE---DDAD
DFESDYEEESYHLAPEEVN---KAPVFVPVGLRSPEPVSAQIEETMEE------------
-----------------------LEITVNVPDVGCIAVVEHELP-NTDVTTEEMKQEENL
SA-PFEMTTSEHIQDE-PGTNDGSTEAAITLLTMGDLVLQSEISSEQGD-VGVCILPHVH
SKDKSHIPSSLDNVNHKIVHECQEL-SSPV-ITTSPASFEENKIVLE--EQSSKEEISLM
EKVKENATPTRNTISKV--TSNLRIRSRLARPKPNLEKTLGTNRLDDYQKVSSLCVTKGA
EMETQRE-TEKNASKA-----------------TELENKNLGPVTTAENKDQ-SKLACVH
GIKGTSIS-SEVNLTERNENQEESSQEVHMLSVAPVASS-ET-------------GPCTL
GLDRGLGENSVEEPQIKDSKGDSVLTLPVPE-----YTPTS-IPEVQQ-ENIINP----Q
DLTVNLVANVPQD-GEDEQAFILTLVEIPTNAVEEFTDATA--QFMPNPLLPAPILVKSV
NTEE-RGDMSIC---LPATSVGQDAMGLSIS---------GRDNS-KKPPDNLDLVSRKR
FQCRLDKNDH--IPPAKKRSL-------TLRDDCQEYTSEVHSKELTNVFEE-TGESHKG
Q-------DIFLTSGSTL-TTPEPQRQQVEAA-FQS---RGSR-SP-DA----CIDKNVP
QLPQDEM---IVSDKEERTDAAPKSQQMDSRTSSSKASLSRPGRRPLGFLSLICSKNS-L
ESDEPMQVHSKKRLKPLIPGLRKKLKRSNPFNESQEKN--RESSDLLPSPSVITTQ----
SENISSSATQVS--CDQPLLKEGYKSAQKRAPQ-GEPTTVSEYFFNDIFIEVDETE----
-----

MFRRARLSVKPNVRPGVGAR------GSTA---SNPQRGRESPRPPEP--ATDSASKPAE
P----TDVPTVDFGGAEPQEKAPRS-S--TEKTGGDND-VEESSRSSSTVSQRRKRISST
SSLVKSSVSVPSESHPLS------------------------------------------
---------------------------------------------------TIN-QEAPQ
PTATSTKEKQPCSDRYRIYKAQKLREMLKEELRKEK--KQWKNKYAINESQRPPDRSKMT
MRDFIYY-LPDNNPMTSSLEQEKKTEKPSTPVQTREQ-EGKSTPNAEDN-----EMEEET
DDGPLLVPRVKVAEDGSIILDEESLTVEVLRTKGPCVVEENDPIFERGST--TTYSSFRK
NYY-SKPWSNKETDMFFLAISMVGTDFSMIGQLFPHRARIEIKNKFKREEKTNGWRIDKA
FQEKRPFDFDFFAHLLQKVLAEEEKRKQKSVKNHSLKEKKSTKPRKNV-KVKKVACEGVN
NDPDE----SMSSRISDTERSQKDAQTVEEE---SLTLSREDAEQVALEVDLNQKKRR--
--RKKQDGANELGVNNLSENATVQAGPSKGEK-HKNKCQAIR----PELKEGECSKEQML
SCTQNIDGIVGF------ASTEKVGK---------RTDPILSLSNQQDAT----------
--S-VAT-ESSESSTSDLPSFEVGIRALC-------------EVNNA-EGSCIEERNVDL
KNNSLEIDQTENVKPMLRGRFQRPKPNLSRA-GKKSVLSQGKTESESKN--SHSKTSVEK
NHVEKDKMNTLDILRMETTER-EN-PEAETVSV------LGEKNCLQEGSQLKA------
--LRPAQV-RGRLQKPKPNAGKAAERKEILISQEEIGANVEKNENESCADRD-------T
PQHMEDQSHKDFEEEEVIL-----QPEKND----SFQNVQPDEPKVLNECLSVQENNKA-
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------NKLNQVPILRTRFQKPKPNIGRGAGRREISSKE-----EVLEKILVSGEM--
---AAALRET----------VRV-DTSPKEMVPAEI-------NT-KEMQSD--------
-LKETGRRAISPRE--KILDVIDVTMEMETGLKAMGG-EICLREKT-PEVIDATEEIDKD
LEEAGRREISPQKNGPEEVKPLGEVETDLKATGN-ESSPREKTP----------------
----------------------------------------EVTDATEEIDKNLEETGRRK
ISPRENGPEEVKPVD-----------------------------EMETDLNATGR-ESSP
REKTPEVIDATEEI--DLKETER-EVSPQENGLEEVK-PLGEMETALKATGR--------
---------------------ESSPRGKTPEVIDAIEEI---------------------
-------EIDLEETEREISPQENGLEEVKPLGEMQTDLKAT-RREISPRE--KTPEVIDA
TEEIDKDLEETGRREISPEENGPEEVKPVDEMETDL--------KATGRESSSREKTREV
--IDAAEVIETDLEETE-R--------------------------------------EIP
PQENG--PEEVKPVGKMETDLKEIREEI------SQRE----------------------
--------KVLAEISAIREKEIDLKETGKRDI-PMMEKVSGKMAVVEEMEADLKETGKE-
NF---R----ERGSEEICVTEE---KVAEL-KQTGKTDISP-REN-----ELEE---TST
SRQ-TDTHLMQSGSNDF-----SAVPSLDIQ-------------------------NISS
EVLSMM-HTPVEEKRNSEKEVSSHFSHFKISSQTH-ESDKTEVQGIQSPDV----PE-QF
SDI---------------------------------------------------------
-----------------------------------------------------------N
LSKSLPQEQ-----------------KPLEIKPAPFVRSRFKRPKPNLARAALKRETTES
EKYIYEK---------KS------------------------------------------
---------ETKKMETIVMRENNEQTDTLPSQHD-EAS--------LMISREKDTSG-HR
NEEAVILPCTQTERNLSP--SNSCEPKEESQSAPVQ--KNDSVVSVGTNN-VNTFQQEMK
ESVIQTAPQVRGRLQRPRPNIRKTGQRQIV---DKGEAK--GIIK-E-------------
-----------GRTILPKDETEKK-VLTVS-----NSQIETEIE-VPSSAVPEHRMY---
------------ENQ-S-----QVILV--ENLHVNKI---NETIRHE-NKPYVPSSAQMT
RRKFQKAKPNLGRAHSKK-EEPVLEKGTTDQ--SKEGKPEDH-LLQKGASNT--QLLLKE
KA---ELLTSLEVSARKDC-VGSKESALAKIDAEFEEVGPSGRVGE----E-----TV-G
DNSPSSVVEEQ--------------------------------------YLNKL---TS-
-----CPQPLKETSYSK-----------------IALDGKTTISSTS----EYERNRGE-
RRSHK-KIK---PNVTRGRGSKRVRGKTSKKEPRASK---AMLVTLRASQEED---DDAD
DFESDYEEESYHLAPEEVN---KAPVFVPVGLRSPEPVSAQIEETMEE------------
-----------------------LEITVNVPDVGCIAVVEHELP-NTDVTTEEMKQEENL
SA-PFEMTTNEHIQDE-PGTNDGSTEAAITLLTMGDLVLQSEISSEQDD-VGICILPHVH
SKDKSHIPSSLDNVNHKIVHECQEL-SSPV-ITTSPASFKENKIVLE--EQSSREEISLM
EKVKENATPTRNTISKV--TSNLRIRSRLAKPKPNLEKTLGTNRLDDYQEVSSLCVTKGA
EMETQRE-TEKNASKA-----------------TELENKNLGPVTTAENKDQ-SKLACVH
GIKGTSIS-SEVNLTERNENQEESFQEVHMLSVAPVASS-ET-------------GPCTL
GLDRGLGENSVEEPQIKDSKGDSVLTLPVPE-----YTPTS-IPEVQQ-ENIINP----Q
DLTVNLVANVPQD-GEDEQAFILTLVEIPTNAVEEFTDATA--QFMPNPLLPAPILVKSV
NTEE-RGDMSIC---LPATSVGQDAMGLSIS---------GRDNS-KKPPDNLDLVSRKR
FQCRLDKNDH--IPPAKKRSL-------TLRDDCQEYTSEVHSKELTNVFEE-TGESHKG
Q-------DIFLTSGSTL-TTPEPQRQQVEAA-FQS---RGSR-SP-DA----CIDKNVP
QLPQDEM---IVSDKEERTDAAPKSQQMDSRTSSSKASLSRPGRRPLGFLSLICSKNS-L
ESDEPMQVHSKKRLKPLIPGLRKKLKRSNPFNESQEKN--RESSDLLPSPSVITTQ----
SENISSSATQVS--CDQPLLKEGYKSAQKRAPQ-GEATTVSEYFFNDIFIEVDETE----
-----

MFRRARLSVKPNVRPGIGAR------GSTA---PNLQRGKESPRPPEP--AAASAPKPAE
P----RDVPLVDTGGAEPQEKAPRG-S--GEKIDGEND-VEESSKSSPTASQRRKRVSST
SSLDKPSVSVPSESHPLC------------------------------------------
---------------------------------------------------TVN-QETLQ
PSPIPTKEKQPCSDRYRIYKAQKLREMLKEELRKEK--KQWKNKYAINESQQPPDRSKMT
MRDFIYY-LPNNNPMTSSLEQEKKTEKSLTPVQTREQ-ESKSTPDAEENE----EMEEET
DDGPLLVPRVKVAEDGSIILDEESLTVEVLRTKGPCVVEENDPIFERGST--TTYSSFRK
NYY-SKPWSNKETDMFFLAISMVGTDFSMIGQLFPHRARIEIKNKFKREEKTNGWRIDKA
FQEKRPFDFDFFAHLLQKVLAEEEKRKQKSVKNQNPKEKKPSKPRKKV-KVKKIVSEGVN
DGLDG----SVSTKISDTEGLLKDTQTAEEEQS-PLTLSEQDSGQIALESDLNQKKRR--
------------------------------------------------------------
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-----

MFRRARLSVKPNVRPGAGGR------GPAA---PEPPRGQQAPREPEP--AAAAAPEAAE
T----PPGPPLDPGGAEPLEDEAAECG--DETPTGDG--AGQSSKSSMTVLQRRKRISTV
PSLTKSSAPASSVPQSLG------------------------------------------
---------------------------------------------------TVQ-EEAPQ
PSPLPVKEKQPCSDRYRILKAQKLREMLREEMTKRRXXXXXXXXXXXXX--XXXXXXXXX
XXXXXXX-XXXXXXXXSSLEQEAKAEKSTPLVQTKDQEEKNTPDGEDDVE----EMEEES
NDGPLLVPRVKVAEDGSIILDEEXXXXXXXXXXXXCVVEENDPIFERGST--TTYSSFRK
NYY-SKPWSNKETDMFFLAISMVGTDFSMIGQLFPHRARIEIKNKFKREEKTNG-RIDKA
FQEKRPFDFDFFARLLEKVLAEEEKRKQKTVKNQNAKEKKSSRPRKKQ-NVNRVASGEVD
DDPDD----SLNARISDMEGTEMDAEIVEKENDQSLNTSG----QTILESVVNRKKRK--
--RKKKDDTDEQEAENLSKEATDPSDTSKGEKPNKKKCQLLV----TVLNGDECNKDLEV
SNLENLDEIICI------PPSENDKN---------ETEHISSTXXXXXXX----------
--XXXXXXXXXX-----XX--XXXXXXXX-------------XXXXX---X-XX--XXXX
XX--X-------XXXXXXXXXX-----XXXXXXXXXXXXXXXXXXXXXXX--X-------
-XX-XX-X--XXXXXXXXXXX--------XXXX----------XXXXXXXXXXX------
--XXXXXXXXXXXXXXXXX--X---X--XXXXXXXXXXXXXXXXXXXXXX---------X
XXXX-XXXXXXXXXXXXXX-----XXXXXX---XXXXXX------XXXXXXXXXXXXXX-
-----------------X---XXX-X-----XXXXX------------------------
---------------------------------------------XXXX-----------
-----------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XLQDGIKSSTLKRGPVMRTRFQKPRPNIGKATGRGEIGRGKISAGEKAPKEISVTGKV--
---EAGLRQT----------XXXXXXXXXXXXXXXX------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
---------------------------------------XX---XXXXXX----------
-----------------------------------X----------------XXXXXXXX
--XX-------------XX-----------------------------------------
--XXX-------------------------------------------------------
------------------------------------------------------------
XX---X---------------X---XXXXX-XXXXXXXXXXXXXXKCFQ-----------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------DEKLSVVKKTPFMRSRFRRPNXXXXXXXXXXXXXXX
XXXXXXX---------XX------------------------------------------
---------XXXXXX--XXXXXXXXXXXXXXXXDTVES--------SQKTAIKYEKPVQE
KGEADVLLNEQTPKKLLD--SMNCEPEERSSFIDAQ--ENNFAVSTGTLS-IKNSQQEIK
KNDIQPAPRTRGRFKRPRPNISKAERRDCR-TAGSWVIE--ERDK-E-------------
-----------EGITQHMNESASE-FFTLX-----XXXXXXXXX-XXXXXXXXXXXX---
----------------------XXXXX--XXXXXXXXXXXXXXXXXDKYKPHTITPAQLR
RSRFQTAKSNLGRVYRKK-EEPGTQKIVPNK--NDTRKVEDK-LLQQGDSDA--HQSLKD
KT---ELLSSLGIAARKEC-VDSRDSALPKECSQS-EQGPDSWALL----V-----TV-G
ATASCVGTEEH--------------------------------------FLNVSPXXXX-
-----XXXXXXXXXXXX-----------------XXXXXXXXXXXXX-------XXX---
-XXXX-XXX---XXXXXXXXXXXXXXX----XXXXXX---XXXXXXXXXXXXXX------
-XXXXXXXXXXXXXXXXXX---XXXXXXXXXXXXXXXXXXXXXXXXXX------------
--------XXXXXXXX------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXEMTTIEYPEEE-TAISDGSTEAAIALLSMGHQMLQSETSPEV---EIVCVLPEDD
LRSHI-STSNPETFDHRVLLEHQVL-SSPV-PSTLLTTLDENKNILE--EQNAGKEMNLP
GQIKEHSTPSSDQSYKK--ISSFRTRSRFPKPKPNISKILGKDRH-IRRKVTSLPSTVDQ
QVDIQSE-TGCTASKE-----------------AVLEDISLESKTMADGMKQASMLTDLH
SFEGTDDG-KEVKQIEXXXXXXXXXXXXXXXXXXXXXXX-XX-------------XXXXX
-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----XCTLNN-APEAEQQNVVT-P----D
NTAVNLVAGEHQG-EEEEQTFILTLVEIPTDSAEQFAGLSD--SLTSGPLLPAPILVKPV
NKEE-RGDVXXX---XXXXXXXXXXXXXXXXX--X-----XXXXX----XXXXXXXXXXX
XXXXXXXXXX-XXXXXXXXXX-------XXXXXXXXXXXXVFSEESTNAYNNAAGESYEK
Q-------TVVPILGSTC-TIAEPPKIEKEQS-EPTVQTSGTE-SS-EEVTCAQEEENVP
HLPQDET---AVSDEQERSEATHQSEQRSK----PSSLFSRPGRRPLGFLSLICSKNN-L
ESEEATPTNSQKRLKPLIPVSRHNVRRPTLVNESKRKK--QDSCSLPPTSAESHSE----
ASTVSSSAPQVS--CDQSFEEEKCKSDQKMETE-EEPTKVTEYFFSDIFMEVDETEQ---
-----

MFRRARLSVKPNVRPSVGAR------GSTA---PNPQRGQESPRPPEP--ATDSASKPAE
P----TDVPAVDFGGAELQEKAPRR-S--SEKTGSDND-VEESSRSSPTVSQRRKRISST
SSLVKASVSVPSESHPLS------------------------------------------
---------------------------------------------------TVN-QEAAQ
PTATPTKEKQPCSDRYRIYKAQKLREMLKEELRKEK--KQWKNKYAINESQRPPDRSKMT
MRDFIYY-LPDNNPMTSSLEQEKKTEKPSTPVQTREQ-EGKSTANAEDN-----EMEEET
DDGPLLVPRVKVAEDGSIILDEESLTVEVLRTKGPCVVEENDPIFERGST--TTYSSFRK
NYY-SKPWSNKETDMFFLAISMVGTDFSMIGQLFPHRARIEIKNKFKREEKTNGWRIDKA
FQEKRPFDFDFFAHLLQKVLAEEEKRKQKSVKNHSLKEKKSTKPRKNV-KVKKIACERVN
DDPDE----SMSSRISDTERSQKDAQTVDEE---SLTLSGKDAKQVALEVDLNQKKRR--
--RKKQDGVNELEVNNLLENATVQAGPSKGEK-HKNKCQAIR----PEVKEGECSKEQML
SCTQNVDGIVGF------ASSEKVEK---------RTDPILSLSNQQDAA----------
--S-VAT-ESSESNTSDLPSLEVGIRASC-------------EVNDA-EGSCTEERNVDL
KSNSQEIDQTENVKPMLRGCFQRPKPNLSRA-GKKSVLSQDKTEAESKN--SHSKTSVEK
DHLEKDKMNTLDILRMETMER-EN-PEAETVSM------LGEKNCLQEESQLKA------
--LTPAKV-RGRLQKPKPNVGKAAGRKEILMSQEEIGANVEKNENESRADRD-------T
-QHMEDQSCKDFEEEDVIL-----QPEKND----SFQNVQPDEPKVLNECLSIQENNKA-
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------NKLNQVPILRTRFQKPKPNIGRGTGRREISSKE-----EVLEKILASGEM--
---TAALRET----------VRL-DTSPKEMVPAEI-------NTTKEMQSD--------
-LKETGRRAISPRE--KILDVIDVTREVETGLKARGR-EICLREKT-PEVIDATKEIDKD
LEETGRREIPPHENGPEEVKPVGEMETNLKATGN-ESSPREKTP----------------
----------------------------------------EVIDATQEIDKDLEDTGKRK
ISPKENGPEEVKPVD-----------------------------EMETDLKATGR-ESSP
REKTPEVIDATEEIEIDLEETER-EISPQENGPEEIK-PLGEMETDLKAAGR--------
---------------------ESSPREKTPEVTDTTEEI---------------------
-------EIDLEETEREISPQENGLEEVKPVGKMETDLKAT-GREISPKE--KTPEVIDA
TEEIDKDLEETGRREISPEENGPEEVKPVDEMETDL--------KATGRESFPREKTPEV
--IDAAEEIEIDVEETE-R--------------------------------------EIA
PQESG--PEEVRPVGKMETDLKEIREEI------SQRE----------------------
--------KVLAEISAVREKEIDLKETGKRDI-SMMEKVSGKMAVIEEMGTDMKETGRE-
NF---R----ERGSEEICVTEE---KVAEL-KKTGKTHISP-REN-----ELEE---TST
SRQ-TETHLMQSGSNDC-----SAMPSLDIK-------------------------NISS
EVLLMM-HTPVEEKRDSEKEVSNPFSHFKISSQTL-ESDKTEVLGIRSPDV----PE-PF
SDI---------------------------------------------------------
-----------------------------------------------------------N
L-RSLPQEQ-----------------KSLEIKPAPFVRSRFKKPKPNLARAALKRETTES
EKYIYGK---------KS------------------------------------------
---------ETKKMETIVMQENNEQADTLPSQHD-EAS--------LMISREKDTSG-HR
NEEAVILPCTQTEKNLSP--SNSCEPKEESQSAQAQ--ENDLVVSVGTNN-INTFQQETK
ESVIQTARPVRGRLQRPRPNVRKTGQRQIV---DKGDAK--GIIK-E-------------
-----------ERTILQKDETEKK-ILTAS-----NPQIETDIE-VPSSTVSEHRMC---
------------ENQ-S-----QVILV--ENLHINKT---DETIRHE-NKLYVPSSAQMT
RRKFQKAKPNLGRAHSKK-EEPILEKSTTDQ--SKEGKPEDH-LLQKGASNT--QLLLKE
KA---ELLTSMEVSARKDC-VGSNESALAKIDAELEEAGPSRRVGE----E-----TV-G
DNSLSSVVEEQ--------------------------------------YLNKL---TS-
-----CPQPLKESNYSK-----------------IALDGKTTISSAS----EYERNRGE-
RRSHR-KIK---PNVTRGRGSKRVRGKTSKKEPRASK---AILVTLRASQEEE---DDAD
DFESDYEEESCHLAPEEVN---KAPVFVPVGLRSPEPVSAQIEETMEE------------
-----------------------LEITVNVPDVGCIAVVEHELP-NTDVTTEEMKQEENL
NASSFEMTTGEHIQDE-PGTSDGSTEAAITLLTMGDLVLQSEISTEQGD-VGVCILPHVH
SKDKSHIPFSLDNVNHKIVHECQEL-SSPV-ITTSPASFEENKIVLE--EQSSREEISLM
EKVKENATPTRNTISKV--TSNLRIRSRLAKPKPNLEKTLGTNRFDDHQEISSLCVTKGE
EMETQRE-TEKSASKA-----------------TELENKNVGPVTTAENKDQ-SKLACVH
GIKGTSIS-PEVNLTERNENQEESSQEVHMLSVAPVASS-ET-------------GPCTL
GLDRGLGENSVEKAQIKDSKGDSVLILPVPE----QYTPTS-IPEVQQ-ENIINP----Q
DLTVNLVANVPQD-GEDEQAFILTLVEIPTNAVEEFTDATA--QFMPNTLLPAPILVKSV
NTEE-RGDMSIC---LPATSVGQDAVGLSIS---------GRDNS-KKPPDNLDLISRKR
FKCRLDENDH--IPPAKKCLL-------TLRDDCQEYTSEVHSKELTNVFEE-TGESHKG
Q-------DIFPTSGSTL-TTPEPQRQQVEPA-FQS---RGSR-SP-DA----CIDKNVP
QLPQDEM---IVSDKEERTDAAPKSEQMDNRTSSSKAPLSRPGRRPLGFLSLICSKNS-L
ESDEPMQVHSKKRLKPLIPALRQKLKRSNPFNESQKKN--QDSSDPLPSPSVINTQ----
SKNISSSATQRP--F---------------------------------------------
-----

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MLKEELRKEK--KQWKNKFATNESQRPPDRSKMT
MRDFIYY-LPDNNPMTSSVEQEKKTEKSLAPTLTRDRQENQSTQDADDNE----EVEEEA
DDGPLLVPRVKVAEDGSIILDEESLTVEVLRTKGPCVVEENDPIFERGST--TTYSSFRK
NYY-SKPWSNKETDMFFLAISMVGTDFSMIGQLFPHRARIEIKNKFKREEKTNGWRIDKA
FQEKRPFDFDFFAHLLQKVLAEEEKRKQKSNKCQSSKEKTS-KPRKNV-KAKKVTNEEVN
DDPDE----SVNSNVSDPERSQKSAQTVAEES---PTSSGQELEQAMVEQDQNQEKRRRR
RRRKNQDEADKQEATNPLGNVHVESTPPVAEIHKN-T-------CPSEENEGECNKEQIP
SFPQNIDDVTGL------ASNEKMEMR---------TDSVTFTCDQQD------------
--IMPLASESLESSGSDFPVSEVGGAASC-------------ELNNA-GSTCMEERNTDL
KNKPPETEQTETVKPKSRSRLQRPKPNLSRAVGKKSVVPQDKQDERNKNS--PSETSSEK
NHVEKERMNISENSGTENIER-ENLGA-ETVSDLSEKS------YIPEDGQPKV------
--LRPARLMRGRMQRPRPNIQKAAERKESPTPQKEIGAHVEKNEDESGVDREKNETCVVI
PQQMENESLKNLQCEEDVI----SQPEKKG---PF-ENVQSDEVKFLDECPSIQEGSKA-
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------NKLKQAPVLRTRFQRPKPKPNTGR--KRMASRG-----GVPEEIPVSREI--
---TATLEET----------TRP-DTSPREKIPNVTIA----TPSTKELESD--------
-LKDTGRNDISSNM--KVSEMTDVTMEMEIGLETFGR-DISPGDMG-GEMIDIPMETETG
-----VNEISP-------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------M---
-EKVPELIDTTEEICTNLEETGRGEIFPQENGPKEVS-PISETETNLQETGKE-------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------LPTKDRTPDM
--IDSNEKGDAHSEETE-----------------RQE---------------------IS
APVKE--AEEARTMGEMETETMGEMERDWRET--SQRE----NTVVAPSEQLVSEVDISS
STCRE---KVGVEWSAVEEKELDLKGTGERD-FSVMAMDSGERTTSEEETNENLKQTGEI
SV---SW---ERGCGEIIVGEE---MVADL-EKTEKVNVFP-RDC-----EPEE----HI
SRQ-LSADVIQSSSDDS-----IPGPSLDRK-------------------------NISN
KT-S-VMSAFVEEKENADKEVSSHLSHTEYSSQNSEQ--HEIDPGIQLPDV----LE-QF
SDT---------------------------------------------------------
-----------------------------------------------------------S
LSKSLP-----------------QEQKPLEVKPAPFLRSRFKKPKPNLSRAALKRATTEA
EHCVPGK---------KS------------------------------------------
---------EADKMVTIMLQQDSKQADSPS--SKHVPS--------LMAPRENDNSGPQ-
-EEAVILPCIQTEKNSSL--SNSCEPKEDSQLTHNQEKENGLVVPIGTQK-VNVVTQETK
QN-VQITLPVRGRLQRPRPNVQKARQRQVV---EKGEAEG--ITK-N-------------
-----------EGSELPKDEAKTS-LAMVN-----SH-IESEVK-VVSFGVSEYSVNES-
--------------H-S-----HVVPV--ENLNINKTSILDEQIR-PENKPHVPSPAQLI
RRRFQRVKPNLGGAHHKK-EQPGIEKDTTDQ--RTAPEPEDR-VLPKGDLDI--QLSLNE
KT---EILTPLEVSERTDC-VVPEESG----------SDRNDAQLKAAPAGGARDETVED
HPTSSLVLEEH--------------------------------------GLSKQI--S--
-----YPQLLKESNYSK-----------------TAPHRRTPLSSAS----ECEIDHSG-
KRAHRKM-K---PSVTKGRGSKRIRGKTAKKEPRAAK---SVLVTLRASQKEDE--DDAE
DFDSDYEEETCHLAPEELN---KAPVFVPVGLRSPEPVSAQIEETMEE------------
-----------------------LEITMDVTDMGCVTVVEHQLS-NMDATTQDVQPGKDL
HSSSFEMVMSEQTQEE-PGPSDGSTEAAITLLAMGDIVLQSEIITEQGD-VGVCVFPDVH
SKDKSHVPFSPDNVNHKIVHDYQEV-SSPV-ISISPASLEENKIVSK--EQSAREEADMM
EEVMENTVSTRNI--EP-T-EHLRMESHFILPEPNSEKILGICGIDGHQEVASVCVTKGT
ELEIQRE-TEENDSKA-----------------IELEDKSLEQT---ETEEQHQL-PYVH
DVEGATVS-QEAILSARSEDQEANLQEVQMSAAA--VASSEI-------------GPHIL
DSGQGLGESPAEEPLKENSKGSSMLMLQVPE----QIVPAN-IPEVQQENMIG-S----Q
DVTVNLFTNLQQD-GEDEQAFILTLVEIPTNATEGFTDASM--QLMPSALLPAPILVKSG
NTVE-RGDLSGS---SQATSVVEDAICLSS----------GN-SDSEKLPAKLDTISRKR
FHCSPDENIP--LPPAKKSAV-------TPAIDCQECASEVCSKEFNV-FEKT-ESCV-G
QG-------IFPTSESTH-TTPQPQKEHNEPT-FQN---AGTR-SP-NEIKDACVEKTMT
QLPQDEMVSDKE----EKTGPVSSSEQRDSMTSSSKPPLTRPGRRPLGFLSLICPKNS-L
DSDEVTQIHSKKRLKPHIPVSRRNLKKSNVVTANQKK---NESSDPLPSPSVTDTQS-DN
PGTSA---SQVS-SDQPLL-KEKCKNGPKRASE-EEATTVSEFVFNDIFIEVDETE----
-----

MFRRARLSVKPNVRPGGGAR---G------SAAPNPQRGPEAPRPPEP--ATEPAPKPAE
PTD--VP--AVDSGGAEPQEKAPGSSFNSDSKTGDENN-VEESSKSSNTVSQRRKRLSST
SSLAKPTVSVPSQCHPI-------------------------------------------
--------------------------------------------------STVN-HDAPQ
PNPTPAKEKQPCSDRYRIYKARKLREMLKEELRKEK--KQWKNKFATNESQRPPDRSKMT
MRDFIYY-LPDNNPMTSSVEQEKKTEKSLAPTLTRDRQENQSTQDADDNE----EVEEEA
DDGPLLVPRVKVAEDGSIILDEESLTVEVLRTKGPCVVEENDPIFERGST--TTYSSFRK
NYY-SKPWSNKETDMFFLAISMVGTDFSMIGQLFPHRARIEIKNKFKREEKTNGWRIDKA
FQEKRPFDFDFFAHLLQKVLAEEEKRKQKSNKCQSSKEKTS-KPRKNV-KAKKVTNEEVN
DDPDE----SVNSNVSDPERSQKSAQTVAEES---PTSSGQELEQAMVEQDQNQEKRRRR
RRRKNQDEADKQEATNPLGNVHVESTPPVAEIHKN-T-------CPSEENEGECNKEQIP
SFPQNIDDVTGL------ASNEKMEMR---------TDSVTFTCDQQD------------
--IMPLASESLESSGSDFPVSEVGGAASC-------------ELNNA-GSTCMEERNTDL
KNKPPETEQTETVKPKSRSRLQRPKPNLSRAVGKKSVVPQDKQDERNKNS--PSETSSEK
NHVEKERMNISENSGTENIER-ENLGA-ETVSDLSEKS------YIPEDGQPKV------
--LRPARLMRGRMQRPRPNIQKAAERKESPTPQKEIGAHVEKNEDESGVDREKNETCVVI
PQQMENESLKNLQCEEDVI----SQPEKKG---PF-ENVQSDEVKFLDECPSIQEGSKA-
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------NKLKQAPVLRTRFQRPKPKPNTGR--KRMASRG-----GVPEEIPVSREI--
---TATLEET----------TRP-DTSPREKIPNVTIA----TPSTKELESD--------
-LKDTGRNDISSNM--KVSEMTDVTMEMEIGLETFGR-DISPGDMG-GEMIDIPMETETG
-----VNEISP-------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------M---
-EKVPELIDTTEEICTNLEETGRGEIFPQENGPKEVS-PISETETNLQETGKE-------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------LPTKDRTPDM
--IDSNEKGDAHSEETE-----------------RQE---------------------IS
APVKE--AEEARTMGEMETETMGEMERDWRET--SQRE----NTVVAPSEQLVSEVDISS
STCRE---KVGVEWSAVEEKELDLKGTGERD-FSVMAMDSGERTTSEEETNENLKQTGEI
SV---SW---ERGCGEIIVGEE---MVADL-EKTEKVNVFP-RDC-----EPEE----HI
SRQ-LSADVIQSSSDDS-----IPGPSLDRK-------------------------NISN
KT-S-VMSAFVEEKENADKEVSSHLSHTEYSSQNSEQ--HEIDPGIQLPDV----LE-QF
SDT---------------------------------------------------------
-----------------------------------------------------------S
LSKSLP-----------------QEQKPLEVKPAPFLRSRFKKPKPNLSRAALKRATTEA
EHCVPGK---------KS------------------------------------------
---------EADKMVTIMLQQDSKQADSPS--SKHVPS--------LMAPRENDNSGPQ-
-EEAVILPCIQTEKNSSL--SNSCEPKEDSQLTHNQEKENGLVVPIGTQK-VNVVTQETK
QN-VQITLPVRGRLQRPRPNVQKARQRQVV---EKGEAEG--ITK-N-------------
-----------EGSELPKDEAKTS-LAMVN-----SH-IESEVK-VVSFGVSEYSVNES-
--------------H-S-----HVVPV--ENLNINKTSILDEQIR-PENKPHVPSPAQLI
RRRFQRVKPNLGGAHHKK-EQPGIEKDTTDQ--RTAPEPEDR-VLPKGDLDI--QLSLNE
KT---EILTPLEVSERTDC-VVPEESG----------SDRNDAQLKAAPAGGARDETVED
HPTSSLVLEEH--------------------------------------GLSKQI--S--
-----YPQLLKESNYSK-----------------TAPHRRTPLSSAS----ECEIDHSG-
KRAHRKM-K---PSVTKGRGSKRIRGKTAKKEPRAAK---SVLVTLRASQKEDE--DDAE
DFDSDYEEETCHLAPEELN---KAPVFVPVGLRSPEPVSAQIEETMEE------------
-----------------------LEITMDVTDMGCVTVVEHQLS-NMDATTQDVQPGKDL
HSSSFEMVMSEQTQEE-PGPSDGSTEAAITLLAMGDIVLQSEIITEQGD-VGVCVFPDVH
SKDKSHVPFSPDNVNHKIVHDYQEV-SSPV-ISISPASLEENKIVSK--EQSAREEADMM
EEVMENTVSTRNI--EP-T-EHLRMESHFILPEPNSEKILGICGIDGHQEVASVCVTKGT
ELEIQRE-TEENDSKA-----------------IELEDKSLEQT---ETEEQHQL-PYVH
DVEGATVS-QEAILSARSEDQEANLQEVQMSAAA--VASSEI-------------GPHIL
DSGQGLGESPAEEPLKENSKGSSMLMLQVPE----QIVPAN-IPEVQQENMIG-S----Q
DVTVNLFTNLQQD-GEDEQAFILTLVEIPTNATEGFTDASM--QLMPSALLPAPILVKSG
NTVE-RGDLSGS---SQATSVVEDAICLSS----------GN-SDSEKLPAKLDTISRKR
FHCSPDENIP--LPPAKKSAV-------TPAIDCQECASEVCSKEFNV-FEKT-ESCV-G
QG-------IFPTSESTH-TTPQPQKEHNEPT-FQN---AGTR-SP-NEIKDACVEKTMT
QLPQDEMVSDKE----EKTGPVSSSEQRDSMTSSSKPPLTRPGRRPLGFLSLICPKNS-L
DSDEVTQIHSKKRLKPHISVSRRNLKKSNVVTANQKK---NESSDPLPSPSVTDTQS-DN
PGTSA---SQVS-SDQPLL-KEKCKNGPKRASE-EEATTVSEFVFNDIFIEVDETE----
-----

MFRRARLSVKPNVRPGVGAR------SSSA---PNPQRGQEAPRPPDP--AAASSPKPAE
S----TDVPPVDFGGTEPQEKPPRS-S--DEKTDNENY-VEESI----------------
------------------------------------------------------------
------------------------------------------------------NQEVPQ
PKPISTKEKQPCSDRYRIYKAQKLREMLKEELRKEK--KQWKNKYAINESQKPPDRSKMT
MRDFIYY-LPDNNPMTSSLEQEKKTEKSLTPVQTRDRQEGKSTPDAEGHE----EVEEEV
DDGPLLVPRVKVAEDGSIILDEESLTVEVLRTKGPCVVEENDPIFERGST--TTYSSFRK
NYY-SKPWSNKETDMFFLAISMVGTDFSMIGQLFPHRARIEIKNKFKREEKTNGWRIDKA
FQEKRPFDFDFFAHLLQKVLAEEEKRKQKSVKNQSSKEKKSSKPRKNV-KAKKVASEGGN
DDPDE----SLSSKISDTEQSQKDAQTGEEEQQ-SQTLPEQDSEQIALETDLNQKKRR--
--RKNQDETGKQEVKNLSGNATVQLDHSKGEK-YINNSQSLR----PEMNEDEGNKEQKL
SCIQNIDDIVDL------SSSEKVEK---------RTDPVLLSSGQQDAM----------
--P-LAA-ETSESSPSDLPSSEVEISTPS-------------EVNNA-ESSCTKESNVNL
KNKSLETDQSGSVKLMARRQLQRPKPNLSRAVGKKSVLSQGKTDAESKSL--HAETSVEK
NQMEKDKVNTSDIAGMEYTEK-VN-PETETVSNCS---SLSEKIGVRDDDQTKA------
--LRPARLMRGRLQRPKPNICKAAERKEILTSQEKIGANVKKNESESCIARD-------N
PEQVEDQSCKNFEFQDITS-----QSEKED-NFFQMN---------VSECLSIQEDNKV-
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------PVLKTRLQKPKPNIGRGARRREVSSKE-----EVSEEIVASGQL--
---TAALGEI----------KRVEETLPREKISLEA-------NSTKEMESH--------
-FKKTRRRDVSPIE--QIAETIDNTVEMETDLKETRG-EISSRENI-SEVSDVIEERVTD
VKETGRE-----------------------------ISSRENISEVSDVIEERVIDLKET
-----------------------------ERAVSSREDVSEMSDVTEERVTDLEETGR--
------------------------------------------------------------
-----------------------------------------------------EVSPRDT
ISAMSDVTEERVTDLEETGR-EVSPRENISEVSDVTEKR---------------------
-------VTDLKETGRAVSPRDSISEMSDVTDERVTDLEET-GREVSIRD--IISEISDV
TEERMTDLEETGRREISLQEDAPEEVSTTDEVETGL--------EETGREISVRENIPEV
--IDVTEERETSVEETERR--------------------------------------EID
TQGKA--LQ-VKTVGEMETDWKEIGKET------SLRA----------------------
--------KVPVEISALGESEIDLEETGEKEL-SLMENVLGKTTAIEETEADMKQSGRAI
SL---R----NPS-SEISATEE---MVADL-GKPREMDISL-RKY-----EAEE---TRT
SRQ-METDLMQSSSGGC-----STVPSLDTK-------------------------NISS
EVLSMV-LTPEAEKRNSEKELSDHLSSLKTSLQTL-ELGKTEDQGMQSPDA----PE-QF
SDN---------------------------------------------------------
-----------------------------------------------------------N
SSKSLPQEQ-----------------KPFEVKPAPFVRSRFKRPKPNLARATLKRETTEA
GKYVPGK---------KL------------------------------------------
---------ETDKAETVVLQQSSEQMNTVPSQHD-VAS--------LMAAGEKDKSG-HS
QEEVVILPCIQTEKDLSP--SSSSGPQEESQPVQAQ--EKELVVSMGAHS-INSSQQESK
ESVVPTIRTVRGRLQRPRPNIRKTGQRHIE----KGEAK--GIVE-E-------------
-----------EKTVVQKD-ETKK-LLTVP-----NSPVGTEIE-VVASKVSEGRLH---
------------ENQ-S-----HMVLV--DPLHVNKVNVLDEKMRPE-PKRYVPSPAQLT
RRQFQKAKPNLGRAHGKK-EELGIEKDRTDQ--SEARKPEDN-LLQPGD-DT--QLLQKE
KA---EFLTSLEVSARKDC-IDSKEAILAKKDTQS-EVGPSGSVGE----K-----TI-V
DNSVSSVVEEQ--------------------------------------CVSKL---TS-
-----PPQLLKESSYSK-----------------IALDRRTTISSAS----ENEVDHGG-
RRMHR-KIK---PNVTRGRGSKRMRSKTSRKEPRASK---STLVTLRASQEEDE--DDAE
DFEPDYEEDSYHLAPEEVN---KAPVFVPIGLRSPEPVTAQIEETMEE------------
-----------------------LEITVNAPDVGCIAVVEHPVS--TNVTTQQMKQEENL
KALSMEMTTGEHTQDE-TGTNDGSTEAAITLLTMGDLVLQSEIGTEQSD--GVCVLLDVH
SKDKSCVPFSPDNVNHKIVRECQEL-SSPV-SSTSPSPLEENKIVLE--EQSTKEEIGLV
EEVKENAISTRNTTSDV--TSNLRMRSRFAKPKPNLKT-LRTSRFGVHQEVPNLFASQGE
VVESQRE-TEKNGSEAM----------------EELQDKKFESLTTALNKEQ-NILACEH
GIEEMTIS-QEANLTERND-QEEESQKVQLFSVDPIVCS-ET-------------KPHTL
GSDMGLGESCIKEPEREDSNGDTVLTLNVSE----CT-PSS-LPEVQQENVIS-S----Q
DLTVNLVANVHQG-GEDEQAFILTLVEIPTNAIEEYTDTTA--QLMPNPLLPAPILIKSV
NTEE-RSDMSMS---FPVTSVGQDAMCISDS---------GREDS-EKLPANLDLITRKR
FHCTLDESDH--VPPAKKSSL-------TSRDDCQNYTSEGCSEEIS---VEETGESYKG
Q-------DTFPTSGSTH-TTPEPQKEQLEPT-LQC---IGSQ-SL-DEIIDTHAETSTP
QLPQNEM---IVSDKEEGTGAASKSEQMGSITAASKTPLSRPGRRPLGFLSLICSKNS-L
ESDEPTHVYNKKRLKPFIPTLRQNLKRSNPLNESQKKT--QESSDLLPSPSVVVNTE---
SENIGSSPAQVS--YDRPLPKEECKTGQTRAPE-EGPTTVSEYFFSDIFIEVDET-----
-----

MFRRARLSVKPNVRPGAGAR------GSTA---PNPQREQEAPRPPEP--AAASVPKPAE
P----TDVPPVDSGEAEPQEKTPKS-S--DEKTDGGNN-VEESSKSSPTVSQRRKRLSST
SSVVKPSVSVPSEPHPLS------------------------------------------
---------------------------------------------------TVNNQEAPQ
PNPVPTKEKQPCSDRFRIYKAQKLREMLKEELRKEK--KQWKNKHAVNENQRPQDRSKMT
MRDFIYY-LPNNNPMTSSLEQEKKTEKSSTPVQTREQ-EGKSTPDGEDNE----EIEEEM
DDGPLLVPRVKVAEDGSIILDEESLTVEVLRTKGPCVVEENDPIFERGST--TTYSSFRK
NYY-SKPWSNKETDMFFLAISMVGTDFSMIGQLFPHRARIEIKNKFKREEKTNGWRIDKA
FQEKRPFDFDFFAHLLQKVLAEEEKRKQKSVKNQSSKEK-SSKSRKNV-KVKKVTNERVS
DDPAE----SVSARISDAEGSQKDTQTVEEEQQ-SLTLSAQDSEQNVVEQDQNQKKRR--
--RKNQGEGGKREVKSLSGNASVQPGSSKGEK-HTN--QSLS----PEINEEGGNKEQNL
PSVQNKDDIVGL------SFSEKTER---------RTDPVLSSSGEQDDV----------
--S-VAA-ETLESGASDLPSSEVGVRPLC-------------EVNNA-ERSCTEERNVDP
KNKSLETDQTENVKPMKRVRLQRPKPNLSRAVGKKTVLLQDKTDEENKS--SHAETSVEK
NHVEKDKTSTSDISVVENTER-EN-PEADAVSN------LSEKICLQEDDAPKV------
--FRPARLMRGSLRRQKPNIGKAAERKGILTSQEKFGATVEKNENESGIGGD-------T
PEQIEDQSCKNFECEDITS-----QSEEKD---TSIQDAQSDDPKALNECPSIQEDNKA-
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------NKQVPVVKTRFQKPKPNIRRTIAKRDISSKK-----EVPEKILASEEI--
---TAALGET----------ASL-ETSPREEVPVET-------NTTKETESG--------
-LKETGK-DSSPRE--KIPEMIDVTVEMETDLKETEMKDISPREKI-PEMSGVTVEMET-
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------DLKET-GREVFPREEEEIPKVTDA
TEERETDLEETVRREISLQENAPEEIDTISEVVTDL--------KETVREISPREKIPDI
--IDAAEEAETDLEESERR--------------------------------------EIS
TQDKV--SEVKTVGDEVDSEVKEIGIEI------SLRE----------------------
--------NVVVGIRDTGEREVDLEETAERDF-SLVEKVSGKMTAIEETEADLKETGKEI
FL---K----KSRPEEISASED---RVADL-EKIRKTDISL-REN-----AREE---TGT
SRQ-TGTDSLQSSSADC-----SAVPSLTNN-------------------------DISS
EILSVV-HTAVEENRNSEKEMSSQLSHLNISLETS-GLDKIEDQRMQSPDV----PE-QS
SDI---------------------------------------------------------
-----------------------------------------------------------N
LSKSLPQEQ-----------------KPSEVKPAPFLRSRFKRPKPNLARAASKREATGA
EKCAPGK---------NM------------------------------------------
---------EPDKVGTVVIQPNSDQMSTLSSQHD-VAS--------LMTSREKDKSD-HS
QEETVILPHGQTEKELSP--SSSHEPKEESQSTQAQ--GKELVVSIGTHD-INTLERES-
--AVQTVPPVRGRLQRPRPNLRRVGQRQVI---EKSEAK--ETNK-E-------------
-----------EGTLQK-DETKKE-FLTVP-----NSQIAPEIE-VVSSKVSEGRTCEIE
VVSAKGSEGRTGENQ-S-----HVVLL--ENLHLNEVNALDEKTRQE-RKTYVPSPPRMI
RRQFQKPKPNLGRAHARK-EESSIEKDRADQ--SEARKPEDN-LLQHGDSDT--QFLQKE
KA---ESLTSLKVSARKDS-VGSQETGLAKKDAQS-EAGPSQSVGE----K-----TV-G
DDSGCSAVEEQ--------------------------------------YLSKP---TR-
-----FPQLPKESNHSR-----------------IALDRRTALSSAS----ECETDHSE-
RRIHR-RVK---PNVTRGRGSKRVRSKTSKKEPRAPK---AVLVTLRASQEEDE--DDAE
DFESDYEEESYHLAPEEVN---KAPVFVPVGLRSPEPVPTQIEETMEE------------
-----------------------LEITVNVPDVGCIAVVEHQLS-NADVTTQEMKQEENL
NASSVEMTTGEHSQDE-TGTNDGSTEAAITLLTMGDLVLQSEISTEQSG-VGVCILPDGH
SEDKSHVPFSPDNINHDIVHEHPEL-SSPL-CSTAPS--EDNKIVLE--EQSTKEETGLV
EEVKENAISTRTTTSEV--TSSLRPRRRFAKPKPNLKKILGTKRFGAHQEVPSLSEI---
----QGE-TEKNASKG-----------------TELEDKNLGSDTTAESKEQ-SKLACVH
GIEETSNS-QEARLTKRNEDHEEGSEEVQMLSAAPLVSS-EP-------------STDTL
ALGTSLGESFIEEPLRKDSDGDSMLTLYVPE----QCPPAS-IPDVQQENVNN------P
QDSVDLLANVHQD-GEDEQAFILTLVEIPTSAVEEYADTTT--QLLPNTLLPAPILVKSV
NKEE-RGDMSVS---FPVIPVDQDAVYLSG-----------RDDS-EKPPANLELLSRKR
FHCSPDESDH--VPPAKKNSL-------TSSDDCQKYTSEVCSKELINL-EE-TGESCQG
Q-------DNFPTLGSTL-TMPEPQKEQLEST-FQS---IGSR-SP-DKVTDTQ-EKNAS
ELPQDEI---MVSDKEERTCAASM--SMDNITSSSKTPLSRPGRRPLGFLSLICSKNS-L
ESDEPTQVHRKKRLKPLIPISRKNLQVSNPLSESQKTT--PEPSDPPPSPSVVANTQSTN
TGNTGSSATQV---SSNPLPKEECKGGQKRVPE-EEPTTISEYFFSDIFIQVDETE----
-----

MFRRARLSVKPNVRHGGGAR------GSAA----KPQRGLEAARPPEP--ATDPSPKPVE
P----TDMPVAVFRGAEPQEKAPTS-S--DEKIDGENN-VEESYTSSSAVSL-RRRLSST
SSLVEPSVSVPSQSPPLP------------------------------------------
---------------------------------------------------TVN-QGVPQ
PNPVRTKEKQLCSDRYRLYKAQKLREMLKEELRKDK--KQWKNKYAINESQMPPDRSKMT
MRDFIYY-LPDNNPMSSSLEQEKKTEKPLTPVQAKDRQESKSALDAEDYE----AAEEET
DDGPLLVPQVKVAEDGSIILDEESLTVEVLRTKGPCVVEENDPIFECGST--TTYSSFRK
NYY-SKPWSNKETDMFFLAISMVGTDFSMIGQLFPHRARIEIKNKFKREEKTNGWRIDKA
FQEKRPFDFDFFAHLLQKVLAEEEKRKQKSTKNQGVKK-KSSKPQKNV-KVKKVTSEVVD
DDPDE----CVSAKISDIEGSQRDAQTVTEE-D-SLTSSGQDA-EVVLEQDQNQKRRR--
--KKNQDGANEQEVQSLSGNAAVPLGFSEAEK-DKNKCQSLR----PEVNESERSEEQMP
SCTQNLDDTVDL------VSSETVEQ---------RKDPILSPSHHHSNI----------
--P-AAT-ESSESSPSPVSPSEVAITALC-------------EVNPA-KQSCIKERNVDQ
KSQSLEASQAENVKPMLRGRLQRPKPNLSRAVGKKLVLSQAKTDAENES--SHSDTSTEK
NHMEKNKMNTFDSGGMENTGK-EN-QEAETMSN------LGEKTCLLEDNQPKA------
--PRSAQPVRGRLPRPKPNVWKVTERKETITSQ-KEGASVEKTQNESCVNKD-------I
LQQMEDQSYKNLECEDKQ-------PEKKD---TSFQNVQPDEPRALNECLSIQEDSQA-
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------NVLKQVPILRTQFQKPKPNIVRGIRRRKIPSKE-----EVPEESPVSGGE--
---TAALREL----------IRP-DTSPGEKVPVVI-------T----------------
----------------------ATSKEMKSNLRETGRRDTSPSENI-AEMSDVTVIMETG
LKATVT------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------ESPPR--EKTPELIDT
TGEIETDWKES-RREIFPQENDPGEVKSIGETEAGL--------QETRRENPTGERTLEM
--IDPTEERGTDLEESERR--------------------------------------EIP
VPGKV--PKELKTIGEVETDLKDIEGEI------SQRE----------------------
--------KVLMGVSTLEEREIDLKETGKEDI-SLMETILRKTIVTEEIEADLKETETEI
SL---R----EREAEQICVIEE---MVADL-EKTGNIDISP-REN-----L-EE---PAT
SRE-IETDVMQKSSADC-----SIVPSLDVK-------------------------NIVS
EVQPVVPTSI--EENNSEKELSDHLSCSKPASQIS-EFYKTEDQGIQPPDV----SE-HF
SDT---------------------------------------------------------
-----------------------------------------------------------N
LSQSLPQEQ-----------------KPLEVKPAPFVRSRFKRPKPNLARATSKKVTTEA
EKYVPEK---------KL------------------------------------------
---------ETNHMETIEIQQDREQANTLPLQPD-VTS--------ILVSREKDKSG-PK
KEETVILPCIQTEKDPAP--S-ACEPAEHSQSVQTQ--ENDLAVPMVIQK-VNTFQQEMK
ETVTQMVLPMRARLQRPKPNVKNARHRQVV---EKGEAK--GMNK-N-------------
-----------ERTVLQKDETNKK-SLIVS-----NSQIETEIE-VVSSRVSECNMD---
------------ENQ-S-----HEVLV--GNLHVNKKNTSDAKMRFE-NKPCVPSPAQLI
RMKFQKTKPDLGRACSRKVEEAGIEKGPADQ--SGASKPEED-SLHQGNLDS--QLLLKE
EA---EIVTSPGISARKDC-IGSEESVLAKKNVQLEEVGSSENVRE----E-----TV-Q
DNSASSVVEEQ--------------------------------------CFSKL---TS-
-----SPQLLKESYYSK-----------------TALDGRTMISSAS----GSEIDHSE-
RRMQR-KIK---TSVTRGRGTKRARAKTSRKEPRAPK---AMLVTLRASQEEDD-DDDAQ
DFESNYEDESCHLAPEEVN---KAPVFVPLGLRSPEPVSAQIEETME-------------
----------------------ELEITVNVADVGCVTVVEHLLS-NTDETIQKLEQENNL
N-MSFEMTTGEQNQDE-AGTSDGSTEAAITLLTMGDLMLQSEMSTDQGD-VGVCVFPDVH
SKDKSHIPFSPDNVSHKIVHECQEL-SSFV-INTSAT--EENKCV-S--EKQNREEVGLK
EEIMENTTSTRSTASKV--DSSFQNRSRFVRPEPNLEV-LVTNRVDAHQEVSG--VSKGD
EVESQKE-TENIASKA-----------------TELEDKNSGPVRTAENQEQ-NQLACVQ
HIKGTSIS-QEANPTARNEDQEENSQEVQMLPVAPNLSS-EA-------------GPPTL
VSSGGLSKNSVEEPLIKDAKGDSVSTLHVPE----CT-PTS-IPEVQQENITN-T----Q
DLTVNLFGNVHQD-GEDEQAFILTLVEIPASAAEEFTDAAA--QLMPSPVLPAPILVKSG
NPKE-KAD------------------------------------------------VRKR
FHCMLDESDQ--VPPTKKSSL-------ILRNDLQQYTSEVCSKEL-NAFEE-KGESHKG
Q-------GISTTSRSTY-TIPEPQKERLEPV-LQN---KESR-SL-DKIIGTCIEKNMP
QLSQDNA---VMSD-EERIDAASKSEQRGVRTKSSKAPLTRSGRRPLGFLALICSKNNLM
ESDEPTHVRSKKRLKPLLPVSRRNLKRSNPPNETQKKN--QESSNVLPSPSDATSTQ---
AEDAGNAATQVS--CDQPSLKEECKSGQKQAPESEEPSTVSEYFFGDIFIKVDEAE----
-----

MFRRARLSVKPNVRPGVGTR---G------SAAPNPQRGPEAPRPPEP--ATESAPKPAE
PTD--VP--AVDSGGAEPQEPAPGSS---DEKTGDKNN-AAESSTLSSASSQRRKRVSST
SSLVQPPGSAPSQSRPL-------------------------------------------
--------------------------------------------------STVD-HDAPQ
PNPTPAKEKQPCSDRYRIYKARKLREMLKEELRKEK--KQWKNKFSANESQRPPDRSKMT
MRDFIYY-LPDNNPMTSSVEQEKKPEKSLAPTPTRDRQENQSTQDANDNE----DVEEEV
DDGPLLVPRVKVAEDGSIILDEESLTVEVLRTKGPCVVEENDPIFERGST--TTYSSFRK
NYY-SKPWSNKETDMFFLAISMVGTDFSMIGQLFPHRARIEIKNKFKREEKTNGWRIDKA
FQEKRPFDFDFFAHLLQKVLAEEEKRKQKSTKCQSLKEKAS-KPRKNL-KAKGVTSEEVN
DDPDE----SVNSNISDPERSQNDAETVNEEE--SPSSSGQHLEQAMLEQDQNQEK----
KRRRNQGEANKQEATNLLERVLVHSSPPAAEIHKN-T-------CPSEENESECNKEQIP
SLTQNIDDIAGL------APSEETEMR---------MDPIPSTCNQQD------------
--IMALARESSESCAAALPVWEPGNTAPA-------------DMAHA-ESSCSEGRAADL
KTVPPETEQTENVKPKSRSRLQRPKPNLARAVGKKSAVSQDRQDERNKNS--PSETAAEK
NHMEKETVNESETSVAKNTDR-ESPGA-KTVSDLSEKS------CVQQDSQAKV------
--LRPTRLMRSRMQRPKPNVVKAAERKEILTSQEKFGAHVEKSE---------GESCVVI
PPQTENESHKNSQCEDT-V----SEPGRKD---PF-ENIQPGQPQVLSDCPSIHEGNKE-
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------NKRKQVPVLRTRFQKPKPNTGRRR--RRISSKE-----GIPEETPISGEI--
---PATWEEI----------PRP-DTSLREEVLSVPLAPLTATASTKDSESD--------
-VKDSGRNDTASNA--EMSEMTDVTMEMETGLETIGR-DTCPGEMG-AEMIDIPMETEAG
L-KASLYETSC-------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------M---
-EKVPELIDTTGEICTNLGETGRKEVFLQENGPKEVS-PVSEPETGLQETGKD-------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------LAMKESTPDT
--TDSTEEREAYSEETE-----------------RQEK--------------------IS
ALIKD--AEEAKARGEMETPLE----EIGGGT--SQRG----KAAGAPVEQSASEEEPHG
SACRE---EVAVESSTAEGKELNLRETGEDD-VSSMVVVLGEKTDIEETNGDPKETERES
SV---SW---ERGSGEIQVGEE---MVEDL-GKPEKIDVAP-RER-----EPEE----HS
SGQ-PEADVILSSSD-G-----STGSPQDKM-------------------------NISS
KI-S-VMPTLVEEKETTDKDISSHLGHVESCSQNLGR--HETDQGMPLPDA----LE-RF
SDT---------------------------------------------------------
-----------------------------------------------------------N
LSKPLP-----------------QEQQPLQVKPAPFLRSRFKKPKPNLSRAALKRAPIEA
EHCVPGK---------KS------------------------------------------
---------EACKVEAAMLQQDSDQAA-LSP-QHNVPS--------LMASRENDKSGHEE
E-EAAILPCTQTEKDPSP--PNSSEPKEGSQLTPNQ--ENGLLVPIGTPM-MNTVTQETR
QNVVQTTLPVRGRLQRPRPNVQKARQRQIV---EKGEARD--VAK-N-------------
-----------EGPELQKDKTRTC-LTVAN-----SSHIESGVAVDMSARVSECQVNES-
--------------Q-S-----HADPV--ENLNVNKASVVHEQMR-HENKPYVPSPALLI
RRRFQKAKPNLGGARRKD-EQPGVEKGRTDE--STALTVEDH-LLQKEDCDT--QLSLQA
RE---KADMPLEVSVRKEC-IHSEESG----------SDRNDAQLNAGPSEGSRDETAKE
QPTS-LGLEEQ--------------------------------------SLSKQIRSS--
-----CPQLLKESSYPK-----------------TVSSRRTPLSSAS----ECEIEHSW-
KRTQRKT-K---PNVTKGRGSKRIRGKTAKKEPRASK---SVLVTLRASQKEDE--DDAE
DFDSDYEEETYHLAPEELS---KAPVFVPVGLRSPEPVSAQIEETMEE------------
-----------------------LEITMDVADM---TVVEHQLS-LMDTTAQAVQAEKVV
YPPSFEMDVGEQTQEE-PGPSDGSTEAAITLLTMGDIVLQSEIFPGQGD-VGVCVFPDVH
SEDKSHAPFNPDNVNQKVVHDCQEV-CSPV-ISTSHASFEENRIVSK--EQSNRDAAV-V
EEAVEETLPTRNTTSTM-S-THLRMESMVVTPELNSEKTLEISESDGHQEVASFCITKGT
EVEIQRE-TEGDDSKA-----------------VELEDKSHAPVTAAETKEEEQS-QCVG
DVEGASVS-QEAILPARIEDHEETLQEVQESGTA--VASSEI-------------GQQTL
DSGQSFGESAAEEALKKTPKGSDVPVLHGPE----S-VPSH-IPEAQQEN-TS-P----Q
AVTVNPFADGQHD-GEDEQAFILTLVEIPTHATEGFTDAAM--QLMPSSLLPAPILVRSG
NAAE-RGDLSGS---LQTSLVVQDAPSLSP----------SRSGNSEKPPANLDLTSRKR
FCCSPDESIH--VPPAKKSSL-------VPGIDYQECTSEVCSEELNV-FEKTAESCM-G
QG-------IFSTSESTH-ATSKPQKEHSEPT---D---TGSSGSL-DEIKDACVEN-MA
QLPQSEIVSDKE----EKTEPASNSEQRDSVTSSSKPPLTRPGRRPLGFLSLLCPKNS-L
ESDEVTQTHSKKRLKPQIPVLRRNLRKPNLHNTSQKKN--QDSSAPLPSPSVTAPLS-DT
AGSPESSATQVC-EHCCVL-L--CMRYIYHL----NEGRKSKFIFSWMSEIILVQLLFPT
KMHLI

MFRRARLSVKPNVRPGVGTR---G------SAAPNPQRGSEAPRPPEP--ATESAPKPAE
PTD--VP--AVDSGGTEPQEQAPGSS---DEKTGDKNN-AAESSTLSSASSQRRKRVSST
SSLVQSPGSAPSQSRPL-------------------------------------------
--------------------------------------------------STVN-HDAPQ
PNPTPAKEKQPCSDRYRIYKARKLREMLKEELRKEK--KQWKNKFSTNESQRPPDRSKMT
MRDFIYY-LPDNNPMTSSVEQEKKPEKSLAPTPTRDRQENQSTQDANDNE----DVEEEV
DDGPLLVPRVKVAEDGSIILDEESLTVEVLRTKGPCVVEENDPIFERGST--TTYSSFRK
NYY-SKPWSNKETDMFFLAISMVGTDFSMIGQLFPHRARIEIKNKFKREEKTNGWRIDKA
FQEKRPFDFDFFAHLLQKVLAEEEKRKQKSTKCQSSKEKAS-KPRKNL-KAKTVTSEEVN
DDPDE----SINSNISDPERSQNDAEAVNEEE--SPSSSGQHLEQAMLEQDQNQEK----
KRRRSQGEANKQEATNLLERVLVHPSPPAAEIHKH-T-------CPSEENESECNKEQIP
CLTQNIDDIAGL------VPSEETEMR---------MDPIPSTCNQQD------------
--IMPLARESSESGAAALPVWEPGSTASA-------------DMANA-ESSCSEGRGADL
KTAAPETEQTENVKPKSRTRLQRPKPNLARAVGKKSAVSQDRQDERDKNS--PSETAAEK
NHMEKETVNESETSVAKNTDR-ASPGA-RTVSDLSEKS------CVQQDGQAKV------
--LRPTRLMRSRMQRPKPNVVKAAERKEILASQEKVEAHVEKSE---------VESCVVI
PPQMENESHKNLQCEDT-V----SLPEKKD---PF-ENTQPDQPKVLSDCPSIQEGNKE-
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------NKRKQVPVLRTRFQKPKPNTGRRR--RR-SSKE-----GIPEETPISGEI--
---AATWEEF----------PRP-DPSLREEILSVPLAPLSATASTKDSESD--------
-VKDNGRNDTASNA--EMSEMTDVTMEMETGLETIGR-DTCPGEMG-AEMIDIPMETEAG
L-KASLNETSC-------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------T---
-EKVPELIDTTGEICTNLGETGRKEVFLQENGPKEVS-PVSEPETGLQETGQD-------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------LGTTESTPDT
--TESTEEREACSEQTD-----------------RQEK--------------------IP
ALTKD--AEEAKASGEMETPLQ----EIGGGT--SQRE----KAAGAPVEQSASEEDPHG
SACRE---EVAVESSTAEGKELNLRETGEDDHVSSMVVVSGEKTAVEETNGDSKETERAS
SV---SW---ESGSEEIQVMEE---MVEDL-GKPEKIDVAP-RES-----EPEQ----QS
SGQ-PEADVILSSSD-G-----STGSPQDEM-------------------------NISS
KI-S-VMPTLVEEKETTDKDVSSHLVHVESCSQNSGH--HETDQGMLLPDA----LE-RF
SDT---------------------------------------------------------
-----------------------------------------------------------N
LSKPLP-----------------QEQQPLQVKPAPFLRSRFKKPKPNLSRAAVKRATIEA
AHSVPGK---------KS------------------------------------------
---------EACTVEAAMLQQDSDQAA-LSP-QHNVPS--------LMASRENDQSGHEE
EEGAAILPCIQTAKEPSP--PSSSDPKEDSQLAQHQ--ENGLVVPIGTSM-MNTVTQETR
QNVVQTTLPVRGRLQRPRPNVQKARQRQIV---EKGEARD--IAK-N-------------
-----------EGPELQKDETRTC-LTVAN-----SSHIESGVAVDMSPRVSQCQVSES-
--------------Q-G-----HADPV--ENLSVNKASVVHEQMR-HENKPYVPSPALLI
RRRFQKAKPNLGGARRKD-EQAGVETGQTDK--STALTAEDH-LLQKGDCDT--HLPLQA
RE---KADMLLEVSVRKEC-VHSEESG----------SDGNDAQLNAGPSEGSKDETVKE
QPPS-SGLEEQ--------------------------------------SLSKPIRSS--
-----CPQLLKESSYPK-----------------TVSSRRTPLSSAS----ECEIEHSW-
KRTQRKT-K---PNVTKGRGSKRIRGKTAKKEPRASK---SMLVTLRASQKEDE--DDAE
DFDSDYEEETYHLAPEELS---KAPVFVPVGLRSPEPVSAQIEETMEE------------
-----------------------LEITMDVADM---TVVEHQLS-HVDTTAQAVQAEKAV
YPPSFEMDIGEQTQEE-PGPSDGSTEAAITLLTMGDIVLQSEIIPGQGD-VGVCVFPDVH
SKDKSHVPFSPDNVNQKIVHDYQEV-CSPV-ISTSHASFEENRIVSK--EQSNRDAAV-V
EEAVEETLPAWNTASTL-S-THLRMASVVVTAELNSEKTLEISESGGHQEVASFCISKGT
QVEIQRE-AEGDDSKA-----------------VELEDKSLAPVTAAEAKEEEHS-QCVG
DVEGASVS-QEAVLPARIEDHEETLREVQVSGTV--VASSEI-------------GQQTL
DSGQSFGESAAEEALKETPKGSDVPVLHGPE----S-VPSH-VPAAQQDS-TS-A----Q
DVTVSLFANGQQD-GEDEQAFILTLVEIPTHATEGFADAAM--QLMPSSLLPAPILVRSG
NAAEPAGDLSGS---LQTSSVVQDATSLSP-----------RSGNSEKPPANLDLTSRKR
FRCSPDESIH--VPPAKKSSL-------VPGIDYQECTSEVCSEELNV-FEKTAESCM-G
QG-------ISPTSESTH-ATSKPQKEHSEPT---D---TGPSGSL-DELKDACVEN-RA
QLPQSEIVSDKE----EKTEPASNSEQRDSVTSSSKPPLTRPGRRPLGFLSLLCPKNS-L
ESDEVTQTHSKKRLKPQIPVSRRNLRKPNLPNTSQKKN--QDSSAPLPSPSVAAPLS-DN
AGSPESSAAQVC-EHCCIL-L--CMRYIYHL----NEGRKSKFIFSWMSETILVQLLFPT
KMLLI

MFRRARLSVKPNVRPSVGAR------GSAA---PNPQRGQESPRPPEP--ATDSSSKPAE
P----TDVSAVHFNGAEPQEKAPRI-S--TEKTASDND-VKESSKSSSTVSQRRKRVSST
SPLVKSSVSVSSESHPLS------------------------------------------
---------------------------------------------------TVN-QEAPQ
PIATPTKEKQPCSDRYRIYKARKLREMLKEELRKEK--KQWKNKYAINESQRPPDRSKMT
MRDFIYY-LPDNNPMTSSLEPEKKTEKPLTSVQKKEQ-EGKRTPNAEDN-----EMEEET
DDGALLVPRVKVAEDGSIILDEESLTVEVLRTKGPCVVEENDPIFERGST--TTYSSFRK
NYY-SKPWSNKETDMFFLAISMVGTDFSMIGQLFPHRARIEIKNKFKREEKTNGWRIDKA
FQEKRPFDFDFFAHLLQKVLAEEEKRKQKSVKNHSLKEKKSTKPRKNV-KVKKVACEGVN
DDPDE----SMSSRVSDTERSQ-DAQTVEEE---SLTLSGEDAEQVALEVDLNQKKRR--
--RKNQDKANELEVNNLLENATVQAGPSKGKK-QKNKCQSVR----PEVKEGECSKEQMP
S----INGIVSS------ASSEKVEK---------RTDPILSLSNQQDVI----------
--A-VAT-EASESSTPDLPSLEVGIRALC-------------EVNNA-VGSYREERNIDL
KEKSLEIDQTENVKPMLRGHFQRPKPNLSRA-GKKSVLSEGKTEAESKN--SHSEISVEK
NHMEKDKMNTLDILRMETTER-ET-PEAETVSI------VGEKKCLQEGNQLKA------
--FRPAQV-RGRLQKPKPNVGKAAKRKEILISQQEIGANVEMNENESCT-----------
SQHMEDQSCKDFEEEDVIS-------EKND----SLQNVQPDEPKVLNECPSVQENNKA-
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------NKRDQVSILRTRFQKPKPNIGRRTGRREISSKE-----EVLEKIAVSGEM--
---TAALRET----------ITP-NTSPREMVAEGI-------STTKEMQSD--------
-LKESGRRAISPRE--KTVDVIDVIMKMETGLKAAGR-EISPKDKT-PEMIDTTKDVDKD
LEETGGRE----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------IFLEENVPEEVK-PIGEMETDLKATGR-ESSSREK
TPEVIDATKEIDKDLEETGR----------------------------------------
---------------REISPQEKGLEEVKPLGEMETDLKAT-GREISPRK--KTPEV---
------------------------------------------------------------
--IDATKEIDIDLEETER---------------------------------------EIS
PQEKG--PEEVKPIGEMETDLKEVREEI------SQRE----------------------
--------KGLVEISAVREREIDLKETGKKGI-SMMEKVSGDMAAIEEMEADLKETGIE-
NF---R----ESGSEEICVTEE---TVAEL-KKTGKTDISP-RES-----ELEE---TST
SRQ-TETHLMQSGSSDC-----SAMPSLDIK-------------------------NISS
EVLSMM-HTPVEEKRSPEKEVSSSLSHFKVSSQTH-ESDKTKVQGLRSPDV----SE-QF
SDI---------------------------------------------------------
-----------------------------------------------------------N
LSKSLPQEQ-----------------KPLEIKPAPFVRSRFKRPKPNLARAALKRETTES
ETCLSGK---------KS------------------------------------------
---------ETKKMKTIVMQENNEQPDTVPFQYD-ETS--------LMISREKDTSG-HR
NEEAVILPCIQTENNLSP--SNSCEPKEDSQSAQAQ--ENDFVVSVGTNN-INTSQQEMK
ESVIPPARPVRGRLQRPRPNVRKTGQRQIV---EKSDAK--GIIK-E-------------
-----------ERTILQRDESEKK-VLIVS-----NSQIETEIE-IPSSTVSEYRMY---
------------ENQ-S-----QVVLV--ENLHVNKTN---KTFSHE-NKPYVPSPVQMT
RRKFQKAKPNLARAQSKK-EEPVLEKGATDQ--SKAGKPEDH-LLQKGDSNT--QFLLKE
KT---ELLTSLEVSARKDY-VGSKESALAKLDAELEV-GPSRRVGE----E-----TV-G
DNS-VSSVVQE--------------------------------------QLNKL---TS-
-----CPQPLKESNYSK-----------------IAPDGKATISSAS----EYERNHGE-
RRMPR-KIK---PNVTRGRGSKRVRGKNSKKEPRAPK---AMLVTLRASQEEE---DDAD
DFESDYEEESYHLAPEEVN---KAPVFVPVGLRSPEPVSAQIEETMEE------------
-----------------------LEITVNVPDVGSIAVVEHQLP-NTDVTTEEMKQEENL
NAPSFEMTTGEHIQDE-PGTNDGSTEAAITLLTMGDLVLQSEISTEQDD-VGVCILPHVH
SKDKSHIPFSLENVNHRIVHECQEL-SSPV-ITTSLPSFEEDKIVLE--EQSSRKEISLM
ENLKENATPTRNTTSKV--TSNSRL-SRFAKPKPHLEKILGTNRLDDYQEVSSLCVTKGE
ELEAQRE-TEKNASKA-----------------TELEDKNLGPVTTAENNEQ-SKLAFVP
GIKGTSIP-QEVNLTERNENQDESSQEVHMLSVAPIASS-ET-------------GPRTL
GLDRGLGENSVEEPQIKDSKGDSVLTLPVPE----YT-PTS-IPEVQQENVIN-P----Q
DLTVNLVANISQD-GEDEQAFILTLVEIPTNAVEEFTDAAA--QLMPNPLLPAPILVKSV
TTEE-RGDVSIC---LPTTSVGQDAMGLSIT---------GRGDS-KKPSDNLDLVSRKR
FHCRLDENDH--IPPAKKCFL-------TFRDDCQEYTSEYPFFQLA-LSF--EGESPKG
Q-------DIFPTSGSTL-TTPEHQKEQVEPD-FQS---IVSR-SP-DR----CIEKNVP
QLPQNEM---FVSDKEERTDAAPKSEQMDK-TSSSKAPLSRPGRRPLGFLSLICSKNS-L
ESDEPTQFHNKKRLKPLIPALRQKFKRSNPVNESQKKN--GESSDPLPSPSVINTQ----
SENISSSATKVS--CDQPLLK-GYKSGQKWAPE-GEPTTVSEYFFNDIFIEVDETE----
-----

MFRRARLSVKPNVRPGVGAR------GSTA---SNPQRGRESPRPPEP--ATDSASKPAE
P----TDVPAVDFGGAEPQEKTRRS-S--TEKTGSDND-VEESSRSSSTVSQRRKRISST
SSMVKSSVSVPSESHPLS------------------------------------------
---------------------------------------------------TVN-QEAPQ
PTATPTKEKQPCSDRYRIYKAQKLREMLKEELRKEK--KQWKNKYAINESQRPPDRSKMT
MRDFIYY-LPDNNPMTSSLEQEKKTEKPSTPVQTR-------------------------
-----------------------DLTVEVLRTKGPCVVEENDPIFERGST--TTYSSFRK
NYY-SKPWSNKETDMFFLAISMVGTDFSMIGQLFPHRARIEIKNKFKREEKTNGWRIDKA
FQEKRPFDFDFFAHLLQKVLAEEEKRKQKSVKNHSLKEKKSTKPRKNV-KVKKVACEGVN
NYPDE----SMSSRISDTERSQKDAQTVEEE---SLTLSREDAEQVALEVDLNQKKR---
--RKKQDGANELEVNNLLENATVQAGPSKGEK-HKNKCQAIR----PEVKEGECSKEQML
SCTQNIDGIVGF------ASTEKVEK---------RTDPILSLSNQQDAP----------
--S-VAT-ESSESSTSDLPSFEVGIRALC-------------EVNNA-EGSCIEERNVDL
KNNSLEIDQIENVKPMLRGRFQRPKPNLSRA-GKKSVLSQGKTEAESKN--SHSKTSVEK
NHVEKDRRNTLDILRMETTER-EN-PEAETISI------LGEKICLQEGSQLKA------
--LRPAQV-RGRLQKPKPNVGKAAERKEILISQEEIEANAEKNENESCADRD-------T
PQHMEDKSCKDFEEEDVIL-----QPEKND----SFQNVQPDKPKVLNECLSVQENNKA-
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------NKLNQVPILRTRFQKPKPNIGRGTGRREISSKE-----EVLEKILASGEM--
---AAAFRET----------VRL-DTSPKEMVPAEI-------NT-KEMQSD--------
-LKETGRRAISSRE--KILDVIDVTMEMETGLKATGR-EICLREKT-PEVIDATEEIDKD
LEETGRREIPPQKNGPEEVKPVGEMETDLKATGN-ESSPREKTP----------------
----------------------------------------EVTDATEEIDKDLEETGRRK
ISPKENGPEEVKPVA-----------------------------EMETDLKATER-ESSP
REKTPEVIDATEEIEIDLEETER-EVSPQENGLEEVK-PLGKMDTDLKATGR--------
---------------------ESSPKEKTLEVIDAIEEV---------------------
-------KIDLEETEREISPQENGLEEVKPLGEMETDLKVT-GRDISPRE--KTPEAIDA
TEEIDKDLKETGRRKISPEENGPEEVKPVDEMEIYL--------KATGRESSPREKIPEV
--IDAAEVIEIDLEETE-R--------------------------------------EIS
PQENG--PEEVKPVGKMETDLKEIREEI------SQRE----------------------
--------KVLAEISAVREKEFDLKETGKRDI-PMMENVSGKMAVIEEMEADLKETGRE-
NF---R----ERGSEEICVTEE---KVAEL-KKTGKTDISP-REN-----ELEE---TST
SRQ-TETNLMQSGSSDC-----SAMPSLDIQ-------------------------NISS
EVLSMM-HTPVEEKRNSEKEVSSHFSHFKISSQAH-ESDKTDVQGFQSPDV----PE-QF
SDI---------------------------------------------------------
-----------------------------------------------------------N
LSKSLPQEQ-----------------KPLEIKTAPFVRSRFKRPKPNLARAALKRETTES
AKCIYGK---------KS------------------------------------------
---------ETKKMETIVMQENNEQADTLPSQHD-EAS--------LMISKDKDTSD-HR
NEEAVILPCTQTERNLSP--SNSCEPKEKSQSALVQ--ENDLVVSVGTNN-INTFQQEMK
ESVIQTARRIRGRLQRPRPNVRKTGQRQIV---DKGEAK--GIIK-E-------------
-----------ERTILPKDETENK-VLTVS-----NSQIETEIE-VPSSAVPEHRMY---
------------ENQ-S-----QVVLV--ENLHVNKT---NETIRHE-NKPYVPSSAQMT
RRKFQKAKPNLGRAHSKK-EEPVLEKGSTDQ--SKEGKPQDH-LLQKGASNT--QLLLKE
KA---ELLTSLEVSARKDC-IGSKESAWAKIDAELEEGGPSRRVGE----E-----TV-G
DNSLSSIVEEQ--------------------------------------YLNKL---KS-
-----CPQPLKETNYSK-----------------IALDGKTTISSTS----EYERNRGE-
RRSHR-KIK---PNVTRGRGSKRVRGKTSKKEPRASKAMKAMLVTLRASQEEE---DDAD
DFESDYEEESYHLAPEEVN---KAPVFVPVGLRSPEPVSAQIEETMEE------------
-----------------------LEITVNVPDVGCIAVVAHELP-NTDVTTEEMKQEENL
SA-PFEMTTSEHIQDE-PGTNDGSTEAAITLLTMGDLVLQSEISSEQGD-VGVCIPPHVH
SKDKSHIPFSLDNVNHKIVHECQEL-SSPV-ITTSPASFEENKIVLE--EQSSREEISLM
EKVKENATPARNTVSKV--TSNVRIRSRLAKPKPNLEKTLGTNRFDDYQEVSSLCVTKGA
EMETQRE-TEKNASKA-----------------TELENKNLGPVTTAENKDQ-SKLACVH
GIKGTSIS-SEVNLTERNENQEESSQEVHMLSVAPVASS-ET-------------GPCTL
GLDRGLGENSVEEPQIKDSKGDTVLTLPVPE-----YTPTS-IPEVQQ-ENIINP----Q
DLTVNLVANVPQD-GEDEQAFILTLVEIPTNAVEEFTDATA--QFMPNPLLPAPILVKSV
NTEE-RGDMSIC---LPATSVGQDAMGLSIS---------GRDNS-KKPPDNLDLISRKR
FQFRLDKNDH--IPPAKKLSV-------TLRDDCQEYTSEVHSKELTNVFEE-TGESHKG
Q-------DIFLTSGSTL-TTPEPQRQPVEPA-FQS---RGSR-SP-DA----RIDKNVP
QLPQDEM---VVSDKEERTDAAPKSQQMDSRTSSSKAPLSRPGRRPLGFLSLICSKNS-L
ESDEPMQVHSKKRLKPLIPALRKKLKRSNPFNESQKKN--RESSDLLQSPSVITTQ----
SENISSSAPQVS--CDQPLLKEGYKSAQKRAPQ-GEPTTVSEYFFNDIFIEVDETE----
-----

MFRRARLSVKPNVRPSVGAR------GSTA---PNPQRGQESPRPPEP--ATDSASKPAE
P----TDVPAVDFGGAEPQEKAPRR-S--SEKTGSDND-VEESSRSSPTVSQRRKRISST
SSLVKASVSVPSESHPLS------------------------------------------
---------------------------------------------------TVN-QEAAQ
PTATPTKEKQPCSDRYRIYKAQKLREMLKEELRKEK--KQWKNKYAINESQRPPDRSKMT
MRDFIYY-LPDNNPMTSSLEQEKKTEKPLTPVQTREQ-EGKSTANAEDN-----EMEEET
DDGPLLVPRVKVAEDGSIILDEESLTVEVVK-----------------------NESFRK
NYY-SKPWSNKETDMFFLAISMVGTDFSMIGQLFPHRARIEIKNKFKREEKTNGWRIDKA
FQEKRPFDFDFFAHLLQKVLAEEEKRKQKSVKNHSLKEKKSTKPRKNV-KVKKIACERVN
DDPDE----SMSSRISDTERSQKDAQTVDEE---SLTLSGKDAEQVALEVDLNQKKRR--
--RKKQDGVNELEVNNLLENATVQAGPSKGEK-HKNKCQAIR----PEVKEGECSKEQML
SCTQNVDGIVGF------ASSEKVEK---------RTDPILSLSNQQDAA----------
--S-VAT-ESSESSTSDLPSLEVGIRASC-------------EVNDA-EGSCTEERNVDL
KNNSQEIDQTENVKPMLRGCFQRPKPNLSRA-GKKSVLSQGKTEAESKN--SHSKTSVEK
DHLEKDKMNTLDILRMETTER-EN-PEAETVSM------LGEKNCLQEESQLKA------
--LTPAKV-RGRLQKPKPNVGKAAGRKEILMSQEEIGANVEKNENESRADRD-------T
-QHMEDQSCKDFEEEDVIL-----QPEKND----SFQNVQPDEPKVLNQCLSIQENNKA-
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------NKLNQVPILRTRFQKPKPNIGRGTGRREISSKE-----EVLEKILASGEM--
---TAALRET----------VRL-DTSPKEMVPAEI-------NTTKEMQSD--------
-LKETGRRAISPRE--KILDVIDVTREVETGLKARGR-EICLREKT-PEVIDATKEIDKD
LEETGRREIPPHENGPEEVKPVGEMETNLKATGN-ESSPREKTP----------------
----------------------------------------EVIDATQEIDKDLEDTGKRK
ISPKENGPEEVKPVD-----------------------------EMETDLKATGR-ESSP
REKTPEVIDATEEIEIDLEETER-ELSPQENGPEEIK-PLGEMETDLKAAGR--------
---------------------ESSPREKTPEVTDTTEEI---------------------
-------EIDLEETEREISPQENGLEEVKPVGKMETDLKAT-GREISPKE--KTPEVIDA
TEKIDKDLEETGRREISPEENGPEEVKPVDEMETDL--------KATGRESFPREKTPEV
--IDAAEEIEIDVEETE-R--------------------------------------EIA
PQESG--PEEVRPVGKMETDLKEIREEI------SQRE----------------------
--------KLLAEISAVREKEIDLKETGKRDI-SMMKKVSGKMAVIEEMGTDMKETGRE-
NF---R----ERGSEEICVTEE---KVAEL-KKTGKTHISP-REN-----ELEE---TST
SRQ-TETHLMQSGSNDC-----SAMPSLDIK-------------------------NISS
EVLLMM-HTPVEEKRDSEKEVSNPFSHFKISSQTL-ESDKTEVLGIRSPDV----PE-PF
SDI---------------------------------------------------------
-----------------------------------------------------------N
LSRSLPQEQ-----------------KSLEIKPAPFVRSRFKKPKPNLARAALKRETTES
EKNIYGK---------KS------------------------------------------
---------ETKKMETIVMQENNEQADTLPSQHD-EAS--------LMISREKDTSG-HR
NEEAVILPCTQTEKNLSL--SNSCEPKEESQSAQAQ--ENDLVVSVGTNN-INTFQQETK
ESVIQTARPVRGRLQRPRPNVRKTGQRQIV---DKGDAK--GIIK-E-------------
-----------ERTILQKDETEKK-ILTAS-----NPQIETDIE-VPSSTVSEHRMC---
------------ENQ-S-----QVILV--ENLHINKT---DETIRHE-NKLYVPSSAQMT
RRKFQKAKPNLGRAHSKK-EEPILEKSTTDQ--SKEGKPEDH-LLQKGASNT--QLLLKE
KA---ELLTSMEVSARKDC-VGSNESALAKIDAELEEAGPSRRVGE----E-----TV-G
DNSLSSVVEEQ--------------------------------------YLNKL---TS-
-----CPQPLKESNYSK-----------------IALDGKTTISSAS----EYERNRGE-
RRSHR-KIK---PNVTRGRGSKRVRGKTSKKEPRASK---AILVTLRASQEEE---DDAD
DFESDYEEESCHLAPEEVN---KAPVFVPVGLRSPEPVSAQIEETMEE------------
-----------------------LEITVNVPDVGCIAVVEHELP-NTDVTTEEMKQEENL
NASSFEMTTGEHIQDE-PGTSDGSTEAAITLLTMGDLVLQSEISTEQGD-VGVCILPHVH
SKDKSHIPFSLDNVNHKIVHECQEL-SSPV-ITTSPASFEENKIVLE--EQSSREEISLM
EKVKENATPTRNTISKV--TSNLRIRSRLAKPKPNLEKTLGTNRFDDHQEISSLCVTKGE
EMETQRE-TEKNASKA-----------------TELENKNVGPVTTAENKDQ-SKLACVH
GIKGTSIS-PEVNLTERNENQEESSQEVHMLSVAPVASS-ET-------------GPCTL
GLDRGLGENSVEEAQIKDSKGDSVLILPVPE-----YTPTS-IPEVQQ-ENIINP----Q
DLTVNLVANVPQD-GEDEQAFILTLVEIPTNAVEEFTDATA--QFMPNPLLPAPILVKSV
NTEE-RGDMSIC---LPATSVGQDAVGLSIS---------GRDNS-KKPPDNLDLISRKR
FKCRLDENDH--IPPAKKCLL-------TLRDDCQEYTSEVHSKELTNVFEE-TGESHKG
Q-------DIFPTSGSTL-TTPEPQRQQVEPA-FQS---RGSR-SP-DA----CIDKNVP
QLPQDEM---IVSDKEERTDAAPKSEQMDNRTSSSKAPLSRPGRRPLGFLSLICSKNS-L
ESDEPMQVHSKKRLKPLIPALRQKLKRSNPFNESQKKN--QDFSDPLPSPSVINTQ----
SKNISSSATQVS--CDQPLLKEGHKSAQKRAPQ-GEPTTVSEYFFNDIFIEVDETE----
-----

MFRRARLSVKPNVRPGTGAR------GSTAPTAPSVQRGQESPRPPEP--AADSASKLAE
P----TDVPVVDFGRAEPQEKAPRS-S--VGKAGDEKD-VEESSKSSFPVSQRRKRLSST
SSVVKPSVSVPTESHPSS------------------------------------------
---------------------------------------------------AVN-QETPQ
PNPIPTKEKQPCSDRYRIYKAQKLREMLREELRKEK--KQWKNKYAINESQRPPDRSKMT
MRDFIYY-LPDNNPMSSSLEQEKKTEKVLTAVQTREQ-EGKSTPDAEDNE----ALEEET
DDGPLLVPRVKVAEDGSIILDEESLTVEVLRTKGPRVVEENDPIFERGST--TTYSSFRK
NYY-SKPWSNKETDMFFLAISMVGTDFSMIGQLFPHRARIEIKNKFKREEKTNGWRIDKA
FQEKRPFDFDFFAHLLQKVLAEEEKRKQKSVKNHSLKEKKSSKPRKNV-KVKKVAREQVN
NDPDA----SVSTKISDTQRSPKDVQTVEEE-D-SLTLSGQDSEQVALEQDLNQKERR--
--RKNQEATNEPEANSLVENATVQSGPSKGEK-HRNKCQSLR----PEVNEDECN-KQQL
SCVQNIDDIVGL------ASSEKVEK---------ITDPILLSSNQQDAM----------
--L-VAT-ESSESGTSDLPSLEVGIRTMC-------------EVNNA-DSSCTEERNADL
KSKSLETDQMENVKPVLRGRLQRPKPNLSRAVGKKSVLSQGKTDAESKN--SHSETSVDK
NPIEKDKVNTLDISGMENTER-EN-PEAKTISN------LSEKKSLQEDDQAKA------
--LRSTRVTRGRLQRPKPNLGKAAERKEIFASLEKIGANVEKNESESCVDRD-------T
LQQMEDESYKNFECEDITT-----QPANKD----SFQDVQPDEPKVLNECLSIQEDKKA-
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------PILKQVPILRPRFQKPKPNIERGTGRKEISSKE-----EVPEETLVSG----
------------------------------------------------------------
------------------------------------------------------------
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-----

MFRRARLSVKPNVRPGVGAR------GSTA---SNPQRGRESPRPPDP--ATDSASKPAE
P----TDVPTVDFGGAEPQEKAPRS-S--TEKTGGDND-VEESSRSSSTVSQRRKRISST
SSLVKSSVSVPSESHPLS------------------------------------------
---------------------------------------------------TIN-QEAPQ
PTATSTKEKQPCSDRYRIYKAQKLREMLKEELRKEK--KQWKNKYAINESQRPPDRSKMT
MRDFIYY-LPDNNPMTSSLEQEKKTEKPSTPVQTREQ-EGKSTPNAEDN-----EMEEET
DDGPLLVPRVKVAEDGSIILDEESLTVEVLRTKGPCVVEENDPIFERGST--TTYSSFRK
NYY-SKPWSNKETDMFFLAISMVGTDFSMIGQLFPHRARIEIKNKFKREEKTNGWRIDKA
FQEKRPFDFDFFAHLLQKVLAEEEKRKQKSVKNHSLKEKKSTKPRKNV-KVKKVACEGVN
NDPDE----SMSSRISDTERSQKDAQTVEEE---SLTLSREDAEQVALEVDLNQKKRR--
--RKKQDGANELGVNNLLENATVQAGPSKGEK-HKNKCQAIR----PELKEGECSKEQML
SCTQNIDGIVGF------ASTEKVEK---------RTDPILSLSNQQDAT----------
--S-VAT-ESSESSTSDLPSFEVGIRALC-------------EVNNA-EGSCIEERNVDL
KNNSLEIDQTENVKPMLRGRFQRPKPNLSRA-GKKSVLSQGKTESESKN--SHSKTSVEK
NHVEKDKMNTLDILRMETTER-EN-PEAETVSV------LGEKNCLQEGSQLKA------
--LRPVQV-RGRLQKPKPNAGKAAERKEILISQEEIGANVEKNENESCADRD-------T
PQHMEDQSRKDFEEEDVIL-----QPEKND----SFQNVQPDEPKVLNECLSVQENNKA-
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------NKLNQVPILRTRFQKPKPNIGRGTGRREISSKE-----EVLEKILVSGEM--
---AAALRET----------VRL-DTSPKEMVPAEI-------NT-KEMQSD--------
-LKETGRRAISPRE--KILDVIDDTIEMETGLKAMGR-EICLREKT-PEVIDATEEIDKD
LEEAGRREISPQKNGPEEVKPLGEVETDLKATGN-ESSPREKTP----------------
----------------------------------------EVTDATEEIDKNLEETGRRK
ISPRENGPEEVKPVD-----------------------------EMETDLNATGR-ESSP
REKTPEVIDATEEI--DLEETER-EVSPQENGLEEVK-PLGEMETDLKATGR--------
---------------------DSFPRGKTPEVIDAIEEI---------------------
-------EIDLEETEREISPQENGLEEVKPLGEMQTDLKAT-GREISPRE--KTPEVIDA
TEEIDKDLEETGRREISPEENGPEEVKPVDEMETDL--------KTTGREGSSREKTREV
--IDAAEVIETDLEETE-R--------------------------------------EIS
PQENG--PEEVKPVGKMETDLKEIREEI------SQRE----------------------
--------KVLAEFSAIREKEIDLKETGKRDI-PIMEKVSGKMAVVEEMEADLKETGKE-
NF---R----ERGSEEICVTEE---KVAEL-KQTGKTDISP-REN-----ELEE---TST
SRQ-TDTHLMQSGSNDF-----SAVPSLDIQ-------------------------NISS
EVLSMM-HTPVEEKRNSEKEVSSHFSHFKISSQTH-ESDKTEVQGIQSPDV----PE-QF
SDI---------------------------------------------------------
-----------------------------------------------------------N
LSKSLPQEQ-----------------KPLEIKPAPFVRSRFKRPKPNLARAALKRETTES
EKYIYEK---------KS------------------------------------------
---------ETKKMETIVMQENNEQTDTLPSQHD-EAS--------LMISREKDTLG-HR
NEEAVILPCTQTERNLSP--SNSCEPKEESQSAPVQ--KNDSVVSVGTNN-VNTFQQEMK
ESVIQTARQVRGRLQRPRPNIRKTGQRQIV---DKGEAK--GIIK-E-------------
-----------GRTILPKDETEKK-VLTVS-----NSQIETEIE-VPSSAVPEHRMY---
------------ENQ-S-----QVVLV--ENLHVNKT---NETIRHE-NKPYVPSSAQMT
RRKFQKAKPNLGRAHSKK-EEPVLEKVTTDQ--SKEGKPEDH-LLQKGASNT--QLLLKE
KA---ELLTSLEVSARKDC-VGSKESALAKIDAELEEVGPSRRVGE----E-----TV-G
DNSPSSVVEEQ--------------------------------------YLNKL---TS-
-----CPQPLNETSYSK-----------------IALDGKTTISSTS----EYERNRGE-
RRSHK-KFK---PNVTRGRGSKRVRGKTSKKEPRASK---AMLVTLRASQEED---DDAD
DFESDYEEESYHLAPEEVN---KAPVFVPVGLRSPEPVSAQIEETMEE------------
-----------------------LEITVNVPDVGCIAVVEHELP-NTDVTTEEMKQEENL
SV-PFEMTTSEHIQDE-PGTNDGSTEAAITLLTMGDLVLQSEISSEQGD-VGVCIIPHVH
SKDKSHIPSSLDNVNHKIVHECQEL-SSPV-ITTSPASFEENKIVLE--EQSSREEISLM
EKVKENATPTRNTISKV--TSNLRIRSRLAKPKPNLEKTLGTNRLDDYQEVSSLCVTKGA
EMETQRE-TEKNASKA-----------------TELENKNLGPVTTAENKDQ-SKLACVH
GIKGTSIS-SEVNLTERNENQEESSQEVHMLSVAPVASS-ET-------------GPCTL
GLDRGLGENSVEEPQIKDSKGDSVLTLPVPE-----YTPTS-IPEVQQ-ENIINP----Q
DLTVNLVANVPQD-GEDEQAFILTLVEIPANAVEEFTDATA--QFMPNPLLPAPILVKSV
NTEE-RGDMSIC---LPATSVGQDAMGLSIS---------GRDNS-KKPPDNLDLVSRKR
FQCRLDKNDH--IPPAKKRSL-------TLRDDCQEYTTEVHSKELTNVFEE-TGESHKG
Q-------DIFLTSGSTL-TTPEPQRQQVEAA-FQS---RGSR-SP-DA----CMDKNVP
QLPQDEM---IVSDKEERTDAAPKSQQMDSRTSSSKASLSRPGRRPLGFLSLICSKNS-L
ESDEPMQVHSKKRLKPLIPGLRKKLKRSNPFNESQEKN--RESSDLLPSPSVITTQ----
SENISSSATQVS--CDQPLLKEGYKSAQKRAPQ-GEATTVSEYFFNDIFIEVDETE----
-----

MFRRARLSVKPNVRPGVGAR------GSAA---PNPQRGQESPRPPEP--ATDSSSKPAE
P----EDVSAVHFDGAEPQEKAPRT-S--TEKTASDND-VKESSKSSSTVSQRRKRISST
SPLVKSSVSVSSESHPLS------------------------------------------
---------------------------------------------------PVN-QVAPQ
PIATPTKEKQPCSDRYRIYKAQKLREMLKEELRKEK--KQWKNKYAVNESQRPLDRSKMT
MRDFIYY-LPDNNPMTSSLEPEKKTEKPLTSVQKKEQ-EGKRTPNAEDN-----EMEEET
DDGALLVPRVKVAEDGSIILDEESLTVEVLRTKGPCVVEENDPIFERGST--TTYSSFRK
NYY-SKPWSNKETDMFFLAISMVGTDFSMIGQLFPHRARIEIKNKFKREEKTNGWRIDKA
FQEKRPFDFDFFAHLLQKVLAEEEKRKQKSVKNNSLKEKKSTKPRKNV-KVKKVACEGVN
DDPDE----SMSSRISDTERSQKDAQTVEEE---SLTLSGEDAEQVVLEVDLNQKKRK--
--RKNQDKANELEVNNLLENAPVQAGPSKGKK-HKDKCQSVS----PDVKEGECSKEQMP
S----IDGIVGS------ASSEKVEK---------RTDPILSLSNQQDVT----------
--S-VAT-EASESSTPDFPSLEVGIKALC-------------EVNNA-VGSCTEERNIDL
KKKSLEIDQTENVKPMLRGHFQRPKPNLSRA-GKKSVPSEGKTEAESKN--SHSETSVEK
NHMEKDKMNKLDILRMENTEK-ET-PEAETVSI------LGE------------------
---KPAQV-RGRLQKPKPNVGKAAQRKEILISQQEIGANVEKNENESCVDRD-------T
PQHMEDQSCEDFEEEDVIL-----QPEKND----SLQNVQPDEPKVLSECLSIQENNKA-
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------NKRDQVSILRTRFQKPKPNIGRRTGRREISSKE-----EVLEKIAVSGEM--
---TAALRET----------ITP-DTSPREMVPADI-------STTKEMQSD--------
-LKESGRRAISPRE--KIVDVIDVTMEMETGLKAAGR-EISSKDKT-PEVIDTTKEIDKY
LEETGGREMSPEENGPEELKPVGEMETDLKATGRESF-SREKTPEVVDATKEIDKDLEE-
-------------------------------------------------------TER-E
ISSQEKGLKEVNPVGEMKTDLKAT------------------------------------
--------------------------------------------------GR-EISSREK
TPEVTDATKEIDKDLEETGR----------------------------------------
---------------REISPQEKGLEEVKRVGEMETDLKAT-GREISPRE--KTPEMIGA
TKEIDKDLEETGRREISPQENGTEEVKHVGEMETDL--------KATGRESFSREKTTEV
--VDTTKETDIDLEETKR---------------------------------------EVS
PQEKG--PEEVKPIGKMETDLKEVREEI------SQRE----------------------
--------KGLVEISGVREREIDLKETGKKGI-SMMEKVSREMAAIEEMEADLKETGRE-
NF---R----ESGSEEICVNEE---TVAEL-KKTGKTDISP-REN-----ELEE---TST
SRQ-TETHLMQSGSSDC-----SAMPSLDIK-------------------------NISS
EVLSIM-HAPVEEKGNPEKEVSSHLSHFKVSSQTH-ESDKTEVQGLQSPDV----PE-QF
SDI---------------------------------------------------------
-----------------------------------------------------------N
LSKSLPQEQ-----------------KPLEIKPAPFVRSRFKRPKPNLARAALKRETTES
EKYVSGK---------KS------------------------------------------
---------ETKKMETIVMQENNEQLDTVPSQYD-EAS--------LMISREKDTSG-HR
NEEAVILPCVQTENNLSP--SNSREPKEDSQSAQAQ--ENDLVVSVGTNH-INTCQQEMK
ESVIPSARPVRGRLQRPRPNVRKAGQKQIV---EKSDAK--VIIK-E-------------
-----------ERTVLQRDESEKK-VLIVS-----NSQIETEIE-IPSSRVSEYRMY---
------------ENQ-S-----QVVLV--ENLPVNKTK---KTVSHE-NKPCVPSPVQMT
RRKFQKAKPNLGRAQSKK-KEPVLEKDTTDQ--SKAGKPDDH-LLQKGDSNT--QFLLKE
KT---EL-TSLEVSARKDY-VGSKESALAKIDAELEV-GPSRRAGE----E-----TV-G
DN-LVSSVVEE--------------------------------------QLNKL---TS-
-----CPQPLKESNYSK-----------------IAPDGKTTIASAS----EYERNHGE-
RRMPK-KIK---PNVTRGRGSKRVRGKNSKKEPRAPK---AMLVTLRASQEEE---DDAD
DFESDYEEESYHLAPEEVN---KAPVFVPVGLRSPEPVSAQIEETMEE------------
-----------------------LEITVNVPDVGSIAVVEHQLP-NTDVTTEEMKQEDNL
NAPSFEMTTGEHIQDE-PGTNDGSTEAAITLLTMGDLVLQSDISTEQDD-VGVCVLPHVH
SKDKSHIPFSLDNVNQRIVHECQEL-SSPV-ITTSLASFEENKIVLE--EQISRKEISLM
ENVKENATPTRNTTSKV--TSNSRI-SRFAKPKPNLEKILGTNKLDDYQEVSSLCVTKRE
ELEAQRE-TEKNASKA-----------------TELEDKNLGPVTTAENKAQ-SKLACVH
GIKGTGIP-QEVNLTERNENQEESSQEVHMLSVAPIASS-ET-------------GPRTL
GLDRGLGENSVEEPQIKDPKGGSVLTLPVPE----YT-PTS-IPEVQQENIIN-P----Q
DLTVNLVANISQD-GEDEQEFILTLVEIPTNAVEEFTDAAA--QLMPNPLLPAPILVKSM
NTEE-RGDVSIC---LPATSVGQDAMGVSIS---------GRDDS-KKPSDNLDLVSRKR
LHCRLDENDH--IPPAKKCLL-------TLRGDYQEYTSEVHSKELTNVEE--TGESPKG
Q-------DIFPTSGSTL-TTPEYQKEQVEPA-FQS---IGSG-SA-DT----CIDKNVP
HLPQNEM---IVSDKEERTDAAPKSEQMDK-TSSTKAPLSRPGRRPLGFLSLICSKNS-L
ESDEPTQFHNKKRLKPLIPALRQKFKRSNPVNESQKKN--GESSDPVPSPSVINTQ----
SENISSSPTKVS--CDQPLLK-GYKSGQKWAPE-GEPTTVSEYFFNDIFIEVDETE----
-----

MFRRARLSVKPNVRHGGGAR------GSAA----KPQRGLEAARPPEP--ATDPSPKPVE
P----TDMPVAVFRGAEPQEKAPTS-S--DEKIDGENN-VEESYTSSSAVSL-RRRLSST
SSLVEPSVSVPSQSPPLP------------------------------------------
---------------------------------------------------TVN-QGVPQ
PNPVRTKEKQLCSDRYRLYKAQKLREMLKEELRKDK--KQWKNKYAINESQMPPDRSKMT
MRDFIYY-LPDNNPMSSSLEQEKKTEKPLTPVQAKDRQESKSALDAEDYE----AAEEET
DDGPLLVPQVKVAEDGSIILDEESLTVEVLRTKGPCVVEENDPIFECGST--TTYSSFRK
NYY-SKPWSNKETDMFFLAISMVGTDFSMIGQLFPHRARIEIKNKFKREEKTNGWRIDKA
FQEKRPFDFDFFAHLLQKVLAEEEKRKQKSTKNQGVKK-KSSKPQKNV-KVKKVTSEVVD
DDPDE----CVSAKISDIEGSQRDAQTVAEE-D-SLTSSGQDA-EVVLEQDQNQKRRR--
--KKNQDGANEQEVQSLSGNAAVPLGFSEAEK-DKNKCQSLR----PEVNESERSEEQMP
SCTQNLDDTVDL------VSSETVEQ---------RKDPILSPSHHHSNI----------
--P-AAT-ESSESSPSPVSPSEVAITALC-------------EVNPA-KQSCIKERNVDQ
KSQSLEASQAENVKPMLRGRLQRPKPNLSRAVGKKLVLSQAKTDAENES--SHSDTSTEK
NHMEKNKMNTFDSGGMENTGK-EN-QEAETMSN------LGEKTCLLEDNQPKA------
--PRSAQPVRGRLPRPKPNVWKVTERKETITSQ-KEGASVEKTQNESCVNKD-------I
LQQMEDQSYKNLECEDKQ-------PEKKD---TSFQNVQPDEPRALNECLSIQEDSQA-
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------NVLKQVPILRTQFQKPKPNIVRGIRRRKIPSKE-----EVPEESPVSGGE--
---TAALREL----------IRP-DTSPGEKVPVVI-------T----------------
----------------------ATSKEMKSNLRETGRRDTSPSENI-AEMSDVTVIMETG
LKATVT------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------ESPPR--EKTPELIDT
TGEIETDWKES-RREIFPQENDPGEVKSIGETEAGL--------QETRRENPTGERTLEM
--IDPTEERGTDLEESERR--------------------------------------EIP
VPGKV--PKELKTIGEVETDLKDIEGEI------SQRE----------------------
--------KVLMGVSTLEEREIDLKETGKEDI-SLMETILRKTIVTEEIEADLKETETEI
SL---R----EREAEQICVIEE---MVADL-EKTGNIDISP-REN-----L-EE---PAT
SRE-IETDVMQKSSADC-----SIVPSLDVK-------------------------NIVS
EVQPVVPTSI--EENNSEKELSDHLSCSKPASQIS-EFYKTEDQGIQPPDV----SE-HF
SDT---------------------------------------------------------
-----------------------------------------------------------N
LSQSLPQEQ-----------------KPLEVKPAPFVRSRFKRPKPNLARATSKKVTTEA
EKYVPEK---------KL------------------------------------------
---------ETNHMETIEIQQDREQANTLPLQPD-VTS--------ILVSREKDKSG-PK
KEETVILPCIQTEKDPAP--S-ACEPAEHSQ----------------IQK-VNTFQQEMK
ETVTQMVLPMRARLQRPKPNVKNARHRQVV---EKGEAK--GMNK-N-------------
-----------ERTVLQKDETNKK-SLIVS-----NSQIETEIE-VVSSRVSECNMD---
------------ENQ-S-----HEVLV--GNLHVNKKNTSDAKMRFE-NKPCVPSPAQLI
RMKFQKTKPDLGRACSRKVEEAGIEKGPADQ--SGASKPEED-SLHQGNLDS--QLLLKE
EA---EIVTSPGISARKDC-IGSEESVLAKKNVQLEEVGSSENVRE----E-----TV-Q
DNSASSVVEEQ--------------------------------------CFSKL---TS-
-----SPQLLKESYYSK-----------------TALDGRTMISSAS----GSEIDHSE-
RRMQR-KIK---TSVTRGRGTKRARAKTSRKEPRAPK---AMLVTLRASQEEDD-DDDAQ
DFESNYEDESCHLAPEEVN---KAPVFVPLGLRSPEPVSAQIEETMEEGCQMKSVSEPIS
MGIKNHVAGMVEHAYNPSTGEAELEITVNVADVGCVTVVEHLLS-NTDETIQKLEQENNL
N-MSFEMTTGEQNQDE-AGTSDGSTEAAITLLTMGDLMLQSEMSTDQGD-VGVCVFPDVH
SKDKSHIPFSPDNVSHKIVHECQEL-SSFV-INTSAT--EENKCV-S--EKQNREEVGLK
EEIMENTTSTRSTASKV--DSSFQNRSRFVRPEPNLEV-LVTNRVDAHQEVSG--VSKGD
EVESQKE-TENIASKA-----------------TELEDKNSGPVRTAENQEQ-NQLACVQ
HIKGTSIS-QEANPTARNEDQEENSQEVQMLPVAPNLSS-EA-------------GPPTL
VSSGGLSKNSVEEPLIKDAKGDSVSTLHVPE----CT-PTS-IPEVQQENITN-T----Q
DLTVNLFGNVHQD-GEDEQAFILTLVEIPASAAEEFTDAAA--QLMPSPVLPAPILVKSG
NPKE-KAD------------------------------------------------VRKR
FHCMLDESDQ--VPPTKKSSL-------ILRNDLQQYTSEVCSKEL-NAFEE-KGESHKG
Q-------GISTTSRSTY-TIPEPQKERLEPV-LQN---KESR-SL-DKIIGTCIEKNMP
QLSQDNA---VMSD-EERIDAASKSEQRGVRTKSSKAPLTRSGRRPLGFLALICSKNNLM
ESDEPTHVRSKKRLKPLLPVSRRNLKRSNPPNETQKKN--QESSNVLPSPSDATSTQ---
AEDAGNAATQVS--CDQPSLKEECKSGQKQAPESEEPSTVSEYFFGDIFIKVDEAE----
-----

---------------------------------AKPHRGLEAARPPEP--AAEPAPKPAE
P----TDVSAPEFGGAEPQEKAPTS-S--DEKIGGENN-VEESCTSSSAVSQRRRRLSST
SSLVKPSVNVPSQSPPLP------------------------------------------
---------------------------------------------------TVN-QDVPQ
SNPVQIKEKQLCSDRYRIYKAQKLREMLKEELRKEK--KQWKNKYAINESQMPPDRSKMT
MRDFIYY-LPDNNPMSSSLEQEKKTEKLLTPVQTREQ-ESKGALDAEDNE----AAEEET
DDGPLLVPRVKVAEDGSIILDEESLTVEVLRTKGPCVVEENDPIFECGST--TTYSSFRK
NYY-SKPWSNKETDMFFLAISMVGTDFSMIGQLFPHRARIEIKNKFKREEKTNGWRIDKA
FQEKRPFDFDFFAHLLQKVLEEEEKRKQKSAKNQGVKK-KSSKPQKTV-KVQKVSSEVVD
DNPDE----CVNTKISDTEGSQKDAQTVLEE-D-SLTPSGQDTE-LVLEQDQNQKKRRM-
--KRNQDGTTEQKVQNLSGNDTIPSGSSEGEK-HKS-----K----PEVNESECSEEQMP
SCTQNLDDTVDL------ASSERVEK---------RKDPILSPSQQHGNT----------
--P-AAN-ESSESSPSALSPSEVEIIALC-------------EVNPA-LQSCARERDVDQ
KSKSLEGSQAENVKPVLRGRLQRPKPNLSRAVGKKLVFSQDKIDAENKNL--HSETSTEK
NHTEKGKMNAFDSGGMENTGK-EN-QEAQTMSN------LSEKTCLLEDNQPKA------
--PRPVQLVRSRLQRPKPNVGKAAERKETVTPQ-KEGASVENTQNESCI-----------
LQQMEAQSCKNLECEDLIK-----QPEKKD---TSFQNVKPDEPRVLNECLSIQEDNQA-
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------NILKQVPVLRTQFQKPKPNIVRGIERKEIASKE-----EIPEESPVSGEV--
---TAALREL----------VRP-DASPGEKVPVVT----T--ATSKQMKSD--------
-FRETGRDTSA-----------------------------SLSESI-PEMTNVTDAMEIG
LK----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------AT-VTESLPRE--KTLELIDA
SGEIETNLEES-RREIFPQENDPEEVKSIGETETGE--------SP------TGERMPEM
--VDATKERETDLEESESK--------------------------------------DTP
VPGKV--PEEVKTISEMETDLKDI-EEI------SQRE----------------------
--------KVLVAVSILGEREIDLKETGKGDI-SLMETILRKMTVTEETEADLKETENQI
SL---R----ERGAEDIGIIGE---MVADL-EKTRNIDISP-KER-----NLEE---PAT
SRQ-TGTDVIQKSGTDC-----STVPSLDNSKLLFEMCEMLMESSVYAGLLSLFLQNIGS
EVQPVV-HTSIE-ESNSEKELSDHLSCSKPASQIS-ELCKTEDQGIQPPDV----SE-HF
SDT---------------------------------------------------------
-----------------------------------------------------------N
LSKSLPQEQ-----------------KPLEVKPAPFVRSRFKRPKPNLARAASKKETTEA
EKYVPEK---------KL------------------------------------------
---------GTNQMETIEIQQDREQADTLSLQP-------------VMASREKDKSG-LE
KEEIVISSCIQTEQDPAP--S-ACEPAEDSQSVQTQ--ENDLAVPVGIQK-VNTLQQEMK
ESITQMVLPTRARLQRPKPNVKNARHRQLL---EKGEAK--GMIK-D-------------
-----------ERTMLQKDETNKK----TS-----NSQIESDIE-VVSSKVSECSMD---
------------ENQ-R-----HEVFV--ENPYVNKKKMSDEKKRLE-NKPCVPTPAQLI
RRKFQNTKPDLGRAHSRKVEEVPIEKGLVDQ--SGASKQEDN-LLHQGNLDS--QLLRKV
KA---EIVTSPEVSARKDY-IGSEETALAKKNAQLAEVGPSENVKE----E-----TI-Q
HISASSIVEEQ--------------------------------------CFSKL---RS-
-----SPQLLKESDYSK-----------------TAPDERTVISSAS----GNERDHSE-
RRTQR-KIK---TTVTRGRGTKRARAKTSRKEPRAPK---AMLVTLRASQEEDDDDDDAQ
DFESNYEEESCHLAPEEVN---KAPVFVPLGLRSPEPVSAQIEETMEE------------
-----------------------LEITVNVADVGCITVVEHQLSSADKRTI------RSG
KILNIEMTTGEHTQDE-AGTSDGSTEAAITLLTMGDLVLQSGMSTEQGD-VGLCVFPDVH
SKDKSHIPFSPDNISHKIVHECQEL-SSPV-ITTSPASEEDKY-V---SEKQNREEVGLK
EKIMENTTSTRSTASKV--DSSLQITSRFVRPEPDLQV-LVTSRVGAHQEVCG--VSRGE
KVESQKE-TENTASKA-----------------TELEDKNPGPVRTEESQEQ-NQLSCVQ
DIKGTSIS-QEANPTARNENQEESSQEVQMLPVAPVLSS-EA-------------GPSTL
VSSGGFGENS--EPLIKDAKGDSIPILHVPE----VK-ESN-ILEVQQENVTN-T----Q
DLTVNLFRDVHQD-GEDEQVFILTLVEIPANAAEEFTDAGA--QLMLNPVLPAPILVKSG
NPEE-KADVSMT---LPVTSVGEDAVSLSNS---------ERDDS-EKPPANLDLISRKR
FHCMLDESDQ--IPPTKKSSL-------TLRNNLQQYASEVCSKEL-NAFEE-TGESYKG
Q-------STATTSRSTY-TTPTPQKEQLEPG-LQN---KESR-AH-DKIIDTRIE-NVP
HLSQHDV---VMSDKEERVVAASTSEQRAGRTKSSKSPLSRSGRRPLGFLALICSKNNLM
ESDEPTQVRSKKRLKPLLPASRRNLKRSNPSDETQKQH--QESSNVLPSPSDAISTQ---
AEEAGSSAAQVS--CNQPSLKEECKSGQKQAPESEEPSTVSEYFFGDIFIKVDEAE----
-----

MFRRARLSVKPNVRPGVGAR------GSTA---SNPQRGRESPRPPEP--ATDSASKPAE
P----TDVPTVDFGGAEPQEKTPRS-S--TEKTGGDND-VEESSRSSSTVSQRRKRISST
SSLVKSSVSVPSESHPLP------------------------------------------
---------------------------------------------------TIN-QEAPQ
PTATSTKEKQPCSDRYRIYKAQKLREMLKEELRKEK--KQWKNKYAINESQRPPDRSKMT
MRDFIYY-LPDNNPMTSSLEQEKKTEKPSTPVQTREQ-EGKSTPNAEDN-----EMEEET
DDGPLLVPRVKVAEDGSIILDEESLTVEVLRTKGPCVVEENDPIFERGST--TTYSSFRK
NYY-SKPWSNKETDMFFLAISMVGTDFSMIGQLFPHRARIEIKNKFKREEKTNGWRIDKA
FQEKRPFDFDFFAHLLQKVLAEEEKRKQKSVKNHSLKEKKSTKPRKNV-KVKKVACEAVN
NDPDE----SMSSRISDTERSQKDAQTVEEE---SLTLSREDAEQVALEVDLNQKKRR--
--RKKQDGANELGVNNLLENATVQAGPSRGEK-HKNKCQAIR----PELKEGECSKEQML
SCTQNIDGIVGF------ASTEKVEK---------RTDPILSLSNQQDAA----------
--S-VAT-ESSESSTSDLPSFEVGIRALC-------------EVNNA-EGSCIEERNVDL
KNNSLEIDQTENVKPMLRGRFQRPKPNLSRA-GKKSVLSQGKTESESKN--SHSKTSVEK
NHLEKDKMNTLDILRMETAER-EN-PEAETVSV------LGEKNCLQEGSQLKA------
--LRPAQV-RGRLQKPKPNAGKAAERKEILISQEEIGTNVEKNENESCADRD-------T
PQHMEDQSRKDFEEEDVIL-----QPEKND----SFQNVQPDEPKVLNECLSVQENNKA-
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------NKLNQVPILRTRFQKPKPNIGRGTGRREISSKE-----EVLEKILVSGEM--
---VAALRET----------VRL-DTSPKEMVPAEI-------NT-KEMQSD--------
-LKETGRRAISPRE--KILDVIDVTMEMETGLKAMGR-EICLREKT-PEVVDATEEIDKD
LEEAGRREISPQKNGPEEVKPLGEMETDLKATGN-ESSPREKTP----------------
----------------------------------------EMTDATEEIDKNLEETGRRK
ISPRENGPEEVKPVD-----------------------------EMETDLNATGR-ESSP
REKTPEVIDATEEI--DLEETER-EVSPQENGLEEVK-PLGEMETDLIATGR--------
---------------------ESSPRGKTPEVIDAIEEI---------------------
-------EIDLEETEREISPQENGLEEVKPLGEMQTDLKAT-GREISPRE--KTPEVIDA
TEEIDKDLEETGRREISPEENGPEGVKPVDEMETDL--------KATGRESSPREKTREV
--IDAAEVIETDLEETE-R--------------------------------------EIS
PQENG--PEEVKPVGKMETDLKEIREEI------SQRE----------------------
--------KVLAEISAIREKEIDLKETGKRDI-PMMEKVSGKMAVVEEMEADLKETGKE-
NF---R----ERGSEEICVTEE---KVAEL-KQTGKTDISP-REN-----ELEE---TST
SRQ-TDTHLMQSGSNDC-----SAMPSLDIQ-------------------------NISS
EVLSMM-HTPVEEKRNSEKEVSSHFSHFKISSQTH-ESDKTEVQGIQSPDV----PE-QF
SDI---------------------------------------------------------
-----------------------------------------------------------N
LSKSLPQEQ-----------------KPLEIKPAPFVRSRFKRPKPNLARAALKRETTES
EKNIYEK---------KS------------------------------------------
---------ETKKMETIVMQENNEQTETLPSQHD-EAS--------LMISREKDTSG-HR
NEEAVILPCTQTERNLSP--SNSCEPKEESQSAPVQ--KNDSVVSVGTNN-INTFQQEMK
ESVIQTARQVRGRLQRPRPNIRKTGQRQIV---DKGEAK--GIIK-E-------------
-----------GRTILSKDETEKK-VLTVS-----DSQIETEIE-VPSSAVPEHRMY---
------------ENQ-S-----QVVLV--ENLHVNKT---NETIRHE-NKPYVPSSAQMT
RRKFQKAKPNLGRAHSKK-EEPVLEKGTTDQ--SKEGKPEDH-LLQKGASNT--QLLLKE
KA---ELLTSLEVSARKDC-VGSKESALAKIDAELEEVGPSRRVGE----E-----TI-G
DNSPSSVVEEQ--------------------------------------YLNEL---AS-
-----CPQPLKETSYSK-----------------IALDGKTTISSTS----EYERNRGE-
RRSHK-KIK---PNVTRGRGSKRVRGKTPKKEPRASK---AMLVTLRASQEEE---DDAD
DFESDYEEESYHLAPEEVN---KAPVFVPVGLRSPEPVSAQIEETMEE------------
-----------------------LEITVNVPDVGCIAVVEHELP-NTDVTTEEMKQQENL
SA-PFEMTTSEHIQDE-PGTNDGSTEAAITLLTMGDLVLQSEISSEQGD-VGVCILPHVH
SKDKSHIPSSLDNVNHKIVHECQEL-SSPV-ITTSPASFEENKIVLE--EQSSKEEISLM
EKVKENATPTRNTISKV--TSNLRIRSRLAKPKPNLEKTLGTNRLDDYQKVSSLCVTKGA
EMETQRE-TEKNASKA-----------------TELENKNLGPVTTAENKDQ-SKLACVH
GIKGTSIS-SEVNLTERNENQEESSQEVHMLSVAPVASS-ET-------------GPCTL
GLDRGLGENSVEEPQIKDSKGDSVLTLPVPE-----YTPTS-IPEVQQEENIINP----Q
DLTVNLVANVPQD-GEDEQAFILTLVEIPTNAVEEFTDATA--QFMPNPLLPAPILVKSV
NTEE-RGDMSIC---LPATSVGQDAMGLSIS---------GRDNS-KKPPDNLDLVSRKR
FQCRLDKNDH--IPPAKKPSL-------TLRDDCQEYTSEVHSKELTNVFEE-TGESHKG
Q-------DIFLTSGSTL-TTPEPQRQQVEAA-FQS---RGSR-SP-DA----CIDKNVP
QLPQDEM---IVSDKEERTDAAPKSQQMDSRTSSSKASLSRPGRRPLGFLSLICSKNS-L
ESDEPMQVHSKKRLKPLIPGLRKKLKRSNPFNESQEKN--RESSDLLPSPSVITTQ----
SENISSSATQVS--CDQPLLKEGYKSAQKRAPQ-GEPTTVSEYFFNDIFIEVDETE----
-----

------------------------------------------------------------
---------------------------SSDDKADSSND-AGETSKATETPTQRRKRISTT
PNLVK-------------------------------------------------------
-----------------------------------KNLPSPLKERPTQETSVTK-EEKLP
TKPAPAKEKRICSDRERILKARKLREMLREELKKER-MKQLKHRPPIIEGRSPPDRSKMT
MRDLIYY-LPENNPMKSSLVEEKKTEKNSTQCQMKE-QEEKSTQDH-------------S
QDGPLLVPRVKVAEDGSIILDEESLTVEVLRTKGPCVVEENDPIFERGST--TTYSSFRK
SFY-TKPWSNKETDMFFLAISMVGTDFSLIGRLFPHRARSEIKNKFKREEKANGWRIDKA
FKEKRPFDFELFAQLLEKVLADEEKRKQKTVRNQKPKEKKPPRPRKKP-KVAKAASTETL
DDQDD----LQEARISDAET-EADAVTAEKENEESLGISEQAEEQVALEPAFAKKRKK--
--RKRKDDP-EEEVDSFPEQLAVPSEIEEERE------------------------ELDT
VIEEKQDGPPTKEEVMFVVESLETFMCFNSSLEVHERTVFVLEPSIVTNDVILETESAQL
GTVNIPDDISQEIQLSNLPVSRIRNERSKIRNNQLV------------------------
------MCEIKTEKPAERGHLQRPKPNFTRSSGKKEAANQEKMEAETSSP--KLVNTAE-
------------------------------------------------------------
------------------------------------------------------------
---------KNIDQSNRSDTTSGEAAEKDD---KIVE-----TVSQSNEITSSQEDSKL-
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------SVLKPTPLKRGRMQRPKPNLGRTVARKDDRSHE-----KDAEEEKAENGEVE
KGVIHHRDEDSGSCLKSDVHED---LQPCI----MML---E-------------------
---------------------RDVSVDS---EKIINK-ESGPEKQEEKNVAS-----SAR
LLRSRFQRPKP-------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------NLRT
ITSRKEV---------------------------------LDK-------AGKC------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------EVLQS-----------
--LESLGKEKSF------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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-----

MFRRARLSVKPNVRPGVGAR------GSAA---PNPQRGRESPRPPEP--AADSASEPAE
P----TDVPAVDFRGAGPQEKASRG-S--DEKTGHEND-VEESSKSSSTVSQRRKRISST
SSLVKPRVSVPSEPHPSS------------------------------------------
---------------------------------------------------SVN-QEALQ
PNSIPGREKQPCSDRYRIYKAQKLREMLREELRKEK--KQWKNKYAINESQRPPDRSKMT
MRDFIYY-LPDNNPMTSSLEQEKRTEKPLTSVQTREQ-ESKSTPDAEDNE----EMEEER
DDGPLLVPRVKVAEDGSIILDEESLTVEVLRTKGPCVVEENDPIFERGST--TTYSSFRK
NYY-SKPWSNKETDMFFLAISMVGTDFSMIGQLFPHRARIEIKNKFKREEKTNGWRIDKA
FQEKRPFDFDFFAHLLQKVLAEEEKRKQKSVKNQSLKEKKSSKPQKSL-KVKKIACEGVN
DDPDE----SVSSRISDTEISQKDAQTVEEE-E-SLTLSGQDSEQVVLEQGLNQNKRR--
--SKNQDEANQQEVNGVLGNATVHLGPSKGEK-HKNKCQPIS----TEVNEDECSKEQKL
SCVQNIGDIVVV------TNNEKSEK---------RTDPILSSSKQRDAM----------
--P-VSI-ESSESSTPDLPSLEVGSRALC-------------EENNA-KSSCTEERNVDL
KKKSLETDQTENIKPILRGRFRKPKPNLSRAVGKKSVLSQGRTEDGESKN-SCSETSVEK
NHMEEDKTNTLDIYGMENAEL-EN-PETETISN------LSEKMCLRENNRP--------
QPFRPARVMRGRLQRPKPNGGEAE-RTEVLIPEKNAEVNVEESESESCVGRD-------T
FQQMDDQSCKNFEHEDVTS-----QHEKKD----ALQNVQLDEPKALNESLR--------
------------------------------------------------------------
------------------------------------------------------------
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-----

MFRRARLSVKPNVRPGVGAR------GSAA---PNPQRGQESPRRPEP--ATDSSSKPAE
P----TDVSAVHFDGAEPQEKAPRV-G--TEKTASDND-VKESSKSSSTVSQRRKRISST
SPLVKSSVSVSSESHSLS------------------------------------------
---------------------------------------------------TVN-QAALQ
PIATPTKEKQPCSDRYRIYKAQKLREMLKEELRKEK--KQWKNKYAINESQRPPDRSKMT
MRDFIYY-LPDNNPMTSSLEPEKKTEKPLTSVQKKEQ-EGKRTPNAEDN-----EMEEET
DDGALLVPRVKVAEDGSIILDEESLTVEVLRTKGPCVVEENDPIFERGST--TTYSSFRK
NYY-SKPWSNKETDMFFLAISMVGTDFSMIGQLFPHRARIEIKNKFKREEKTNGWRIDKA
FQEKRPFDFDFFAHLLQKVLAEEEKRKQKSVKNHSLKEKKSTKPRKNV-KVKKVACEGVN
DDPDE----SMSSRISDTERSQKDAQTVEEE---SLTLSGEDAEQVALEVDLNQKKQR--
--RKNQDKANELEVNNLLENATVQAGPSKGKK-HKNKCQSVR----PEVKEGECSKEQMP
S----IDGIVGS------ASSEKVEK---------RTDPIHSLSNQQDVT----------
--S-VAT-EASESSIPDLPSLEVGIRALC-------------EVNNA-VGSCTEERNIDL
KKKSLEIDQTENVKPMLRGHFQRPKPNLSRA-GKKSVLSEGKTEAENKN--SHSETSVEK
NHMEKDKMNTLDILRMETAER-ET-PEAETVSI------LGEKKCLQEGNQLKA------
--FRPAQV-RGRLQKPKPNVGKAAERKEILVSQQEIGANVEMNENESCT-----------
PQHMEDQSCKDFEEEGVIL-----QPEKND----SLQNVQPDEPKVLSECLSIQENNKA-
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------NKRDQVSILRTRFQKPKPNIGRRTGRREISSKE-----ELLEKIAVSGEM--
---TAALRET----------VTP-DTSPREMVAEDI-------STTKEMQSD--------
-LKELGGRAISPRE--KIVDVIDVTMEMETGLKAAGR-EISPKDKT-PEVTDTTKEIDKY
LEETGGREISPEENGPEEVKPVGKMETDLKATGRESF-SREKTPEVIDATKEIDKDLEE-
-------------------------------------------------------TER-E
ISSQEKGLKEVKPVGEMKTDLKATGR------------------------------KISP
REKAPEVTDATKEIDKDLEEIGRREISLEENGPEEVK-PVGEMETDLKATGR-ESSSREK
TPEVIDATKEIDKDLEETGR----------------------------------------
---------------REISPQEKGLEEVKPVGEMETNLKAT-GREISPRE--KVPEVIDA
TKEIDKDLEETGRREISPEENGSEDIKHVGEMETDL--------KATGRESSSREKTPEV
--VDATKEIDIDLEETER---------------------------------------EIS
PQEKG--PEEVKPIGKMETDLKEVREEI------SQRE----------------------
--------KGLVEINAVREREIDLKETGKEDI-SMMEKVSGEMAAIEEMEADLKVTGIE-
NF---R----ESGSEEICVTEE---TVAEL-KKTGKTDISP-REN-----ELEE---TST
SKQ-TETHLMQSGSSDC-----SAMPSLDIK-------------------------NISS
EVLSMM-HTPVEEKRNPEKE-SSNLSHFKVSSQTH-ESDKTEVQGLRSPDV----PE-QF
SDI---------------------------------------------------------
-----------------------------------------------------------N
LSKSLPQEQ-----------------KPLEIKPAPFVRSRFKRPKPNLARAALKRETTES
EKYVSGK---------KS------------------------------------------
---------ETKKMETVVMQENNEQPDTVPSQYD-ETS--------LMISREKDTSG-HR
NEEAVILPRIQTENNLSP--SNSCEPKEDSQSAQAQ--ENDLVVSVGTNN-INTCQQEMK
ESVIPTARPVRGRLQRPRPNVRKAGQRQIV---EKSDAK--GVIK-K-------------
-----------ERTILQRDESEKK-VLIVS-----NSQIETEIE-IPSSTVSEYRMY---
------------ENQ-S-----QVVLV--ENLHVNKTN---KTVSHE-NKPYVPSPVQMT
RRKFQKAKPNLGRAQSKK-EEPVLEKGTADQ---KAGKPDDH-LLQKGDSNT--QFLLKE
KT---ELLTSLEVSARKDY-VGSEESALAKIDAELEEGGPSRRVGE----E-----TV-G
DNS-VSSVVEE--------------------------------------QLNKL---TS-
-----CPQPLKESNYSK-----------------IAPDGKTTISSAS----EYERNHGE-
RRMPR-KIK---PNVTRGRGSKRVRGKNSKKEPRAPK---AMLVTLRASQEEE---DDAD
DFESDYEEESYHLAPEEVN---KAPVFVPIGLRSPEPVSAQIEETMEE------------
-----------------------LEITVNVPDVGSIAVVEHQLP-NTDVTTEEMKQEENL
NAPSFEMTTGEHIQDE-PGTNDGSTEAAITLLTMGDLVLQSGISTEQGD-VGVCILPHVH
SKDKSHIPFSLDNVNHRIVHECQEF-SSPV-ITTSLASFEENKIVLG--EQSSRKEISLM
ENVKENATPTRNTTSKV--TSNSRI-SRFAKPKPNLEKILGTHRLDDYQEVSSLCVTKGE
ELEAQRE-TEKNASKA-----------------TELEDKNLGPVTTAENKEQ-SKLACVH
GIKGTSIP-QEVNLTERNENQEESSQEVHMLSVAPIASS-ET-------------GPRTL
GLDRGLGENSVEEPQIKDPKGDSVLTLPVPE----YT-PTS-IPEVQQENIIN-P----Q
DLT---------D-GEDEQAFILTLVEIPTNAP------LQ--QLMPNPLLPAPILVKSV
NTEE-RGDVSIC---LPATSVGQDAMGLSIS---------GRDDS-KKPSDNLDLVSRKR
FHCRLDENDH--IPPAKKCLL-------TLRDDCQEYTSEYPFFQLA-LSF--EGESPKG
Q-------DIFPTSESTL-TTPEHQKEQVELA-FQS---IGSR-SP-DT----CIDKNVP
QLPQNEM---IVSDKEERTDAAPKSEQMDK-TSSSKAPLSRPGRRPLGFLSLICSKNS-L
ESDEPTQFHNKKRLKPLIPALRQKFKRSNPVNESQKKN--EESSDPLPSPSVINTQ----
SENISSSATKVS--CDQPLLK-GYKSGQKWAPE-GEPTTVSEYFFNDIFIEVDETE----
-----

---RARLSVKPNVRPGVGAR------CSAA---GPAQRGREAPRPPEP--AAAADPKPAE
I----TDVPPVDCGAAKPPEEAPRS-S--NEKTDGKND-VEESSKSSSAVSQRRKRISST
PTLVKPSVSVPSEPHPLS------------------------------------------
---------------------------------------------------TVN-QEDPQ
PHPIPTKEKQPCSDRYRIYKAQKLREMLKEELRKEKQRKQAQRGYAINESQRPPDRSKMT
MRDFIYY-LPDSNPMTSSLEQEKKTEKSLTPVQTREQ-EDKSTPDVEDNE----ELEEEM
DDGPLLVPRVKVAEDGSIILDEESLTVEVLRTKGPCVVEENDPIFERGST--TTYSSFRK
NYY-SKPWSNKETDMFFLAISMVGTDFSMIGQLFPHRGRIEIKNKFKREEKTNGWRIDKA
FQEKRPFDFDFFAHLLQKVLAEEEKRKQKSLKNQSLREKKSSKPRKNV-KVKKVASEGVT
DNPDE----SVSATISDTEESQKDAQTVQEELQ-SLTLSGQDSEQIALEADLNLEK-R--
--RKNQDEVGKQEVKNLSGNATVQPGPSKGEK-QKDKCPFLR----PERNEDEGNKEQKL
SCVQTFNEVEDL------SSRDEVVN---------KTDPLLSLSSQQDAT----------
--S-VTT-GASESITSDLHSSEVGIRVLC-------------EVNNA-ESSCTEERNVEL
KNTSLETDQAENVQPMVRGRFQRPKPNLSRAVGKKPILSQGKTDAKSKNL--HPEASVEK
THVEKDKMNSFDISGMENTAR-EN-SEADTVSN------LSEKMNLQEDNQPKA------
--FRPARL-RARLQRPKPNVVKAAERKEILASQEEIGANVEKNENESCVDIN-------T
PQQTEDQSCD------ITS-----QSEKKD---TSFQNVQPDEPKSLNECPSIQEDNEA-
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------NILKQVPALKNRFQKPKPNIGRRTGRRDISSKE-----EVPEEIVVSGKK--
---TAARL----------------ETSPKEKVPVEA-------STTKETESK--------
-LKETGRRDISLRE--KKPEMTDFTVETETDLKETGR-EISPREKI-LEVTGAIEEREAD
LEETEKREIST-------------------------------------------------
------------------------------------------------------------
---QEKGPEVYTVG-EEEAGLKEPGR-EISPRE-EIPEVT--------------------
------MTNVTEERETDLEETR--------------------------------------
------------------------------------------------------------
--------------RREISTQEKAPEVYT-VGEVGTDLNET-GMVISPREEIPEVTMTNA
NEERELDLEETEKREISTQEKAPE-VNTVGEAEAGL--------KEPGRKISPRKEIPEV
TMTNTAAERETDLKETRRR--------------------------------------EIP
TQEKA--QED-RIIGEVEADLKEIGKET------FSKE----------------------
--------KVLVGISAIGKREINLKETGKRDI-SLMERM----AVFKVTEADLKETGRQI
SL---R----KIGSEEISATEE---MVAGL-DKTEKIGISL-REN-----EPEV---TGT
SLQ-TETDLMQSRSADC-----SAVPSLNIK-------------------------NISS
EVLSVV-HTPVEEKGNSEKEVSSQLSHWKTSLKTS-ELAKTEDQGTPCADV----PE-QF
SDI---------------------------------------------------------
-----------------------------------------------------------N
SSKSLPQEQ-----------------KPF--KPAPFMRSRFKRPKPNLSRAALKRETMEA
EKHVPGK---------KL------------------------------------------
---------EVDKIETIMIQQDGEQMNILPSQYD-LSS--------LMTSREKDKSD-HR
QEEAGMLPCELTEKNLSP--SSFCESEEVSQSTQAQ--EKELLISMGTHNNINTFQQEKK
ESIIHSTRPVRGRLQRPRPNIKKALQRQMV---EKGEAK--GIVE-E-------------
-----------ERTKLQKDETKKK-FLSVP-----NYQIGTEIE-VISSKVSEGRMY---
------------ENQ-S-----HAALL--ENLHVNKVDVLDKKMRNE-HKTYVSSPAQLI
RRQFQSPEPNLGRAHDKK-EERVIEKDRADL--DEAWKPEDN-LLQQGDSDT--QLLQKE
KA---ELLTSLEVSARKDC-VGSEEAGLAKKDLQS-EVEPSGSVGQ----K-----TV-G
DNSVSSVVEEQ--------------------------------------HLSKL---AS-
-----HSQLLKESNYSK-----------------IALNQRTAISSAS----GYEMDHTE-
RRMHR-KIK---PTVSKGRGSKRIRSKTSKKEPRAPK---AMLVTLRASQEEDE--DDVE
DFESAYEEESYHLAPEEIN---KAPVFVPVGLRSPEPVSTHIEETMEE------------
-----------------------LEITVNVPDIGFITVDEHQLS-NTDVTTQEMKQEENL
NVLSVEMTTGEHTQDE-TETNDGSTEAAITLLTMGDLVLQSEISTEQSDAIGICVLPGVH
SKDKSHIPFNPDNVSDKIVYECQEL-SSPV-NSVPLSSLEENKIELE--EQSTKEEIGLM
EKVKENARSTRNTTSEV--TSNLRMRRRFAKPKPNLRKILGTNRFGAHQEVPSLLVTKGE
V-EIQRE-TEKNTPKA-----------------TGLEDKNLESETIAENKEQ-SRLAHDH
GIEETSIL-QEASLKERKEDQAQGSQEVQILSFTPVVSS-ET-------------SSHTL
GLGRGLSESSVGEPLGKDSSGDNVLTPYVPE----CI-PTS-TPEVQQENVSN-P----Q
DLAVNLVGNVHHD-AEEEQAFILTLVEIPTDSVEEFTENST--QLMPNPLLPAPILVKSV
TSEE-KSNMSMN---FPITSVGQDAMCLSNS---------GSDAS-EKPPANLDLMSRKR
FHCRSDESDH--VPPAKKHSL-------TLRDDCQEYTSEVCSKELINVFEE-TGKSYKG
Q-------NIFPTSKSTH-TTPEPQKEQLEAT-FQS---MGSR-PL-DKIIDTHIEKNTP
HLPQDKV---IVSDKEEGTCAASKSEQVDSITSSSKTPLSRPGRRPLGFLSLICSKNS-L
ESDEPTHVHRKKRLKPLIPISRQNLKRSNPLSESQKKV--QESSNIHPSPSVVNTQ----
SENIGSSATQVS--CDRSLPKEECKSVQNQALE-EEPTTVSEYFFSDIFIEVDKTE----
-----

MFRRARLSVKPNVRPGVGAR------GSAA---PNPQRGRESPRPPEP--ATDSSSKPAE
P----KDASAVHFDAAEPQEKAPRI-S--TEKTASDND-VKESSKSSSTVSQRRKRISS-
TPLVKSSVSVSSESHPLS------------------------------------------
---------------------------------------------------TVN-QAAPQ
PVATPTKEKQPCSDRYRIYKAQKLREMLKEELRKEK--KQWKNKYAVNESQRPPDRSKMT
MRDFIYY-LPDNNPMTSSLEPEKKTEKPLTSVQKKEQ-EGKRTPNAEDN-----EMEEET
DDGALLVPRVKVAEDGSIILDEESLTVEVLRTKGPCVVEENDPIFERGST--TTYSSFRK
NYY-SKPWSNKETDMFFLAISMVGTDFSMIGQLFPHRARIEIKNKFKREEKTNGWRIDKA
FQEKRPFDFDFFAHLLQKVLAEEEKRKQKSVKNHSLKEKKSTKPWKNV-KVKKVACEGVN
DDPDE----SMSSRISDTERSQKDAQTVEEE---FLTSSGEDAEQVALEIDLNQKKRR--
--RKNQDKASELEVNNLLENAPGEAGPSKGKK-HKDKCQSIS----PDVKEGECSKEQMP
S----IDGIVGS------ASSEKTEK---------GTDPILSLSHQQDVT----------
--S-VATAEASESSTLDLPSLEVGIRALC-------------EVNNA-VGSCTEERNIDL
KKNSLEIDQTENVKPMLRGHLQRPKPNLSRA-GKKSVLSEGKTEAESKN--SHSETSVEK
NHMEKDKTNMLDNLRTETTER-ET-PEAETVSI------LGEKKCLQEGNQLKA------
--FKPAQV-RGRLQKPKPNVGKAAERREILISQQEIGANVEKNENESCVGRD-------T
PQYMEYQLCKDFEEEDVIL-----QPEKNY----SLQNVQPDEPKVLSEYLSIQENNKA-
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------NKHDQVSILRTRFQKPKPNIGRRTGRREISSKE-----EVLEKIAVSGEM--
---TAALRET----------ITP-DTSPREMGPADT-------STTKEMQSD--------
-LKESGRRAISPRQ--KIVDVIDVTMEMETGLKAAGR-EISPKDKT-PEVIDTTKEIDNY
LEETGGREISPEENGPEELKPIGEMETDLKATGRESF-SRENTPEVIDATKEIDKDLEE-
-------------------------------------------------------TER-E
ISPQEKGLEEVKPVGKMETDLKAT------------------------------------
--------------------------------------------------GR-EISPR--
------------------------------------------------------------
-------------------------------------------------E--QTPEVTDA
TKEIDKDLEETGRREISPQKNGPEEGKHVGEMETDL--------KATGRESSSREKTPEV
--VDATKEIDIDLEEIKR---------------------------------------EIS
SQEKG--LEEVKPVGKMETDLKEVIEEI------SQRE----------------------
--------KGLVEISAVREREIDLKETG-KGI-SMMEKVSGEMAAIEEMKADLKETGRE-
NF---R----ESGSEEICVTEE---TVAEL-KKTGKTDISP-REN-----ELEE---TST
SRQ-TETHLMQSGSSDC-----SAMPSLDTK-------------------------NISS
KVLSIM-HTPVEEKRNPEKEVSSCLSHFKVSSQTH-ESDKTEVQGLQSPDV----PE-QF
SDI---------------------------------------------------------
-----------------------------------------------------------N
LSKSLPQEQ-----------------KPLEIKPAPFVRSRFKRPKPNLARAALKRETAES
EKYVSGK---------KS------------------------------------------
---------ETKKMETIVLQENNEQLDMVPSQYD-ETS--------LVIPREKDTLG-HK
NEEAVILPCIQPENNLSP--SNSPEPKEDSQSAQAQ--ENDLVVSVGTNN-INTCQQEMK
ESVIPTARPVRGRLQRPRPNVRKAGQRQI----EKSEAK--DIIQ-E-------------
-----------ERTILQRDESEKK-VLIVS-----NSQVETEIE-IPSSTVSEYRMY---
------------ENQ-S-----QVVLV--ENLHVNKTN---KTVSHE-NKPYVPSAVQMT
-RKFQKAKPNLGRAQSKK-EEPVLEKGTADQ--SKASKPDNH-LLQKGDSNT--QFLLKE
KT---ELLTSLEVSARKDY-VGPKESALAKRDVELEV-GPSGRVGE----E-----TV-G
DNNSVSSVVEE--------------------------------------QLNKL---TS-
-----CPQLLKESNYSK-----------------IAPDGKTTISSAS----DYERNHGE-
RRMPR-KIK---PNVTRGRGSKRVRGKNSKKEPRAPK---AMLVTLRASQEEE---DDAD
DFESDYEEESYHLAPEEVN---KAPVFVPVGLRSPEPVSAQIEETMEE------------
-----------------------LEITVNVPDVGSIAVVEHQLP-NTDVTTEEMKQ-ENL
NAPSFEMTTGEHIQDE-PGTNDGSTEAAITLLTMGDLVLQSEISTEQDD-VGVCILPHVH
SKDKSHIPFSLDNVNHRIVHECQEL-SSPV-ITTSLASFEENKIVLE--EQSSRKEISLM
ENVKENATPTRNTTSKV--TSNSRI-SRFAKPKPNLEKILGTNRLDDYQEVSSLCVTKGE
EPEAQRE-TEKNASKA-----------------TELEDKNLGPVTAAENKEQ-SKLACVH
GIKGTSIP-QEVNLTERNENQEESFQEVHMFSAAPIASS-ET-------------GPGTL
GLDRGLGENSVEDPQIKDRKGGSVLTLPVPE----YA-PTG-IPEVQQENIIN-P----Q
DLTVNLVANISQD-GEDEQAFILTLVEIPTNAVEEFTDAAA--QLMPNPLLPAPILVKSM
NTEE-GGDVSIC---LPATSVGQDAMGLSIS---------GRDDS-KKPSDNLDLVSRKR
FHCRLDENDH--IPPAKKCLL-------ALRDDCQEYTSEVRSKELTNVGE--TGESPKG
Q-------DIFLTSGSTL-TTPEHQKEQVEPA-FQS---IGSR-SP-DT----CRDKNVP
QLPQNEM---IVSDKEKRTDAAPKSEQMDK-TSSTKAPLSRPGRRPLGFLSLICSKNS-L
ESDEPTEFHNKKRLKPLIPALRQKFKRSNPVNESQKKN--GESSDPVPSPSVINTQ----
SENISSSATKVS--CDQPLLK-GYKSGQKWAPE-GEPTTVSEYFFNDIFIEVDETE----
-----

MFRRARLAVRPNVRPV-----GRGAGGAADAEPQGS--------PAAS--R---------
-DE--AGA---------AESLPAGRRADSDEKTNSSSD-AGEASKPTDMPTQRRKRISTM
PNLVKPRAGPSSGLHTASKPQR--RASQAPDGSASLQKDSPPSEKSHAESSSKSPMLPEK
KTPVPQVPQFSPLKKSMNKEQTVAAQ--R-NDDTLKSVPSPLKERPTQETSVAQ-EEKLP
PKPSPVKEKRICSDRERILKARKLREMLKEELKKER-MKQLKHRPPIIEGCSPPDRSKMT
MRDLIYY-LPENNPMKSSLAEEKRTEKSSALGQTKE-QEEKSTPDHEEEDEEEAENGEES
QDGPLLVPRVKVAEDGSIILDEESLTVEVLRTKGPCVVEENDPIFERGST--TTYSSFRK
SFY-TKPWSNKETDMFFLAISMVGTDFSLIGRLFPHRARAEIKNKFKREEKANGWRIDKA
FK-KRPFDFELFAQLLEKVLADEEKRRQKTVKSQKPKEKKPLRPRKKP-KG-KVANTETT
DNQDD----LQEARISDAET-EADTVTAEKENKESLGVSEEAEEQVSLEATLVNKKRK--
--RKRKGDL-EQEVENRPEELAVTSKIPEEGKSSK-KTGKKMANDTNAAGHTLCREELGS
VIEEEQDDLHAKEQER-----SLSFISMD---DITERESDVNLCSFQDSSDKLVTEPTKL
QSLDVTGDTSQESQFSECPVSQTRSKERQLEEARET------TCADT-HGLHEPEEKQNA
SERDSQSQIMKTEKPAERRRLQKPKPNIMKLPGKKEAVNHEKMEAETSSP--NLVNITEK
CSEE-----NSEGNRSEITEV-ES-MDLDTKSEGPE-KTVS-------------------
----AVARIRGSRQRFKPNLTRASGR------------KEHE-NN-SENDKM-------S
QPESKEETEKNTDQSRKFDVTDGEAAEKDD---KVSE-----MVSQSNETTGSQEGSKQ-
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------SVLKPAPLKRGRVQKPKPNLGRTVAWKKDHSHE-----KDPEEEKVEGGEAE
GHVVHHVNEGNDSCHKNDMVGAP-KKSPQK------------------------------
------LKDVE-----NEKGSSDVLKDV---SDFNTG-ESGPGNQEDKTVIS-----SVR
LLRSRFHRPKP-------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------NLRT
TS-RKEVTDINKG-VSQED-TNKKESSMQSTDEC-CVLLDTDK-------AENC------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------EVLQS-----------
--LESLGKEKSVGPQDVSESSSFK-SPD---TLPRSED-----------GKVEPCLLVDN
Q-------------NETSSTNAGIDREIT-----TQGE--SKQTPLQPVQLVRSG-FQKY
KPNL----GKGVRRKELQ-----IPEDNEDKK-SE-------------------A--DEL
EV---QK-------TE---SVH---HVSAI-GKKEA------------------------
-AL-HEENVLSNEEP---------------------------------------------
-----------------------------------------------AQE------E-VP
QMP---------------------------------------------------------
-----------------------------------------------------------C
ISGNLLCEQI--------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------RS---NE-KLSSGEESN
QCDTKPSQQARVSLRNPKPNLTRAHRKRSH---SED-R----NRR-D-------------
-----------KDNAETRN---TE-EHLLE-----K----------------TG---VS-
--------------V-K-----NSS-------NTEEAASFTESTGKHDSTDSVERPSRKR
IRKI-------SSSF----QSPEVP----L-------ESESQ-VEQE-DSQL--SAPQQK
------------------------------------KSDDQT------------------
-----------------------------------------------------R--RQ--
-----SRRLSKQITLPK-----------------HGLELRTGSSSAP----ECEADCCE-
KGNQRQEVK---SSVIRGKSMKTAHRKKPVKEQRSSK---TSSLVTLRASQEDE--EEAD
DFE--PDDDDECFALEEVN---KAPVFVPVGLRSPKPIPVQIEETMEE------------
-----------------------LDISVNIPDVPVATNVEGPS--YVSV-QPAIQKEKGN
TL-PAELTVHENPELD-KGISDGSTEAAMTLLAMGDPTFQLKANTE----EWTRMLPAQD
EVNIANSLVSHD-DSEQNIAPNQYVVSSATSAK--VPCKDGSNINVE--DRSTCAGTGVE
EYFEKDATDARNSSLPM-VNSMTLRRGSLQKSNPNTGV-LKSNE-SVIQNPLNTNVVMEQ
LDSIQSE-SMD---SR-----------------GTTEAQKVEQVSVGPTLRDTSVLQDFA
T-SVELVK-QI----DNKGRTQEEMKDV-------------CGTSGNL-------SPGCE
KSHLGLEDYLDEGSVDRTAVQNPCPAKDSQCTLGFAQNETH-AQDCAQQHISS-T----E
ETSV-NNY-PRCP-EEEEQTFILTLVEILANSEEFDTSALQ--EQTSEPLLPAPILISPV
KSSG-TSLTEV----ESIGSLTTAADELGEYSNSGTETKQQESASVESVLTLVHT-AQKR
SAAEPAENDV----PLVKKTVST-VVESNVEGPCQGYS-----SKSTNTQTRTSDDPFQK
TGVSAKENILASALLS---ISPVDERSQC-ET-LEN---SGKA-SF-HNLASSQEEEMTC
GLTSSTETEISEQGKLGDKHEAAQLECTESLTESSKTPLLS-------------RKSS-S
ESAEEVQRKREKIPNPQTGTTKPSLKNT---TPSSKDD--KES-CSFPSTSTSSFVE-Y-
-DSVPADAVVVAPHNEPSEKPPHCAGD--QEKE-EEPTKISEYFFSDIFMEVDDPE----
-----

MFRRARLSVKPNVRPSVGAR------GSTA---PNPQRGQESPRPPEP--ATDTASKPAE
P----TDVPAVDFGGAEPQEKAPRS-S--SEKTGSDND-VEESSRSSPTVSQRRKRISST
SSLVKASVSVPSESHPLS------------------------------------------
---------------------------------------------------TVN-QEAAQ
PTATSTKEKQPCSDRYRIYKAQKLREMLKEELRKEK--KQWKNKFAINESQRPPDRSKMT
MRDFIYY-LPDNNPMTSSLEQEKKTEKSSTPVQTREQ-EGKSTANAEDN-----EMEEET
DDGPLLVPRVKVAEDGSIILDEESLTVEVLRTKGPCVVEENDPIFERGST--TTYSSFRK
NYY-SKPWSNKETDMFFLAISMVGTDFSMIGQLFPHRARIEIKNKFKREEKTNGWRIDKA
FQEKRPFDFDFFAHLLQKVLAEEEKRKQKSVKNHSLKEKKSTKPRKNV-KVKKIACERVN
DDPDE----SMSSRISDTERSQKDAQTVDEE---SLTLSGKDAEQVALEVDLNQKKRR--
--RKKQDGANELEVNNLLENATVQAGPSKGEK-HKNKCQAIR----PEVKEGECSKEQML
SCTQNVDGIVGF------ASSEKVEK---------RTDPILSLSNQQDAA----------
--S-VAT-KSSESSTSDLPSLEVGIRASC-------------EVNDA-EGSCTEERNVDL
KNNSLEIDQTENVKPMLRGRFQKPKPNLSRA-GKKSVLSQGKTEAESKN--SHSKTSVEK
DHLEKDKMNTLDILRMETTER-EN-PEAETVSM------LGEKNCLQEESQLKA------
--LTPAKV-RGRLQKPKPNVGKAAGRKEILMSQEEIGANVEKNENESRADRD-------T
-QHMEDQSCKDFEEEDVIL-----QPEKND----SFQNVQPDEPKVLNECLSIQENNKA-
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------NKLNQVPILRTRFQKPKPNIGRGTGRREISSKE-----EVLEKILASGEM--
---TAALRET----------VRL-DTSPKEMVPAEI-------NTTKEMQSD--------
-LKETGRRAISPRE--KILDVIDVTREVETGLKARGR-EICLKEKT-PEVIDATKEIDKD
LEETGRREIPPHENGPEKVKPVGEMETNLKATGN-ESSPREKTP----------------
----------------------------------------EVIDATQEIDKDLEDTGKRK
ISPKENGPEEVKPVD-----------------------------EMERGLKATGR-ESSS
REKTPEVIDATEEIEIDLEETER-EISPQENGPEEVK-PLGEMEMDLKAAGR--------
---------------------ESSPREKTAEVTDTTEEI---------------------
-------EIDLEETEREISPQENGLEEVKPVGEMETDLKAT-GREISPRE--KTPEVIDA
TEEIDKDLEETGRREISPEENGPEEVKPVDEMETDL--------KATGRESFPREETPEV
--IDAAEEIEIDVEETE-R--------------------------------------EIA
PQESG--PEEVRPVGKMGTDLKEIREEV------SQRE----------------------
--------KVLAEISAVREKEIDLKETGKRDI-SMTEKVSGKMAVIEEMETDMKETGRE-
NF---R----ERGSEEICVTEE---KVAEL-KKTGKTDISL-REN-----ELEE---TST
SRQ-TETHLMQSGSNDC-----SAMPSLDIK-------------------------NISS
EVLLMM-HTPVEEKRDSEKEVSSPFSHFKVSSQTL-ESDKTEVLGIRSPDV----PE-PF
SDT---------------------------------------------------------
-----------------------------------------------------------N
LSRSLPQEQ-----------------KSLEINPAPFVRSRFKRPKPNLARAALKRETTES
EKYIYGK---------KS------------------------------------------
---------ETKKMENIVMQENNEQADTLPSQHD-EAS--------LMISREKDTSG-HR
SEEAVILPCTQTEKNLSP--SNSCEPKEESQSAQAQ--ENDLVVSVGTNN-INTFQQEMK
ESVIQTARPVRGRLQRPRPNVRKTGQRQIV---DKGDAK--GIIK-E-------------
-----------ERTILQKDETEKK-ILTAS-----NPQIETDIE-VPSSTVSEHRMC---
------------ENQ-S-----QVILV--ENLHINKT---DETIRHE-NKLYVPSSAQMT
RRKFQKAKPNLGRAHSKK-EEPILEKGTTDQ--SKEGKPEDH-LLQKGASNT--QLLLKE
KA---ELLTSMEVSARKDC-VGSNESALAKIDAELEEAGPSRRVGE----E-----TV-G
DNSLSSVVEEQ--------------------------------------YLNKL---TS-
-----CPQPLKESNYSK-----------------IALDGKTTISSAS----EYERNRGE-
RRSHR-KIK---PNVTRGRGSKRVRGKTSKKEPRASK---AILVTLRASQEEE---DDAD
DFESDYEEESCHLAPEEVN---KAPVFVPVGLRSPEPVSAQIEETMEE------------
-----------------------LEITVNVPDVGCIAVVEHELP-NTDVTTEEMKQEENL
NASSFEMTTGEHIQDE-PGTSDGSTEAAITLLTMGDLVLQSEISTEQGD-VGVCILPHVH
SKDKSHIPFSLDNVNHKIVHECQEL-SSPV-ITTSPASFEENKIVLE--EQSSREEISLM
E-IKENATPTRNTISKV--TSNLRIRSRLAKPKPNLEKTLGTNRFDDHQEISSLCVTKGE
EMETQRE-TEKNASKA-----------------TELENKNLGPVTTAENKDQ-SKLACVH
GIKGTSIS-PEVNLTERNENQEESSQEVHMLSVAPVASS-ET-------------GPCTL
GLDRGLGENSVEEAQIKDSKGDSVLILPVPE----N------------------------
-----LVANVPQD-GEDEQAFILTLVEIPTNAVEEFTDATA--QFMPNPLLPAPILVKSV
NTEE-RGDMSIC---LPATSVGQDAVGLSIS---------GRDNS-KKPLDNLDLISRKR
FKCRLDENDH--IPPAKKCLL-------TLRDDCQEYTSEVHSKELTNVFEE-TGESHKG
Q-------DIFPTSGSTL-TTPEPQRQQVEPA-FQS---RGSR-SP-DA----CIDKNVP
LLPQDEM---IVSDKEERTDAAPKSEQMDNRTSSSKAPLFRPGRRPLGFLSLICSKNS-L
ESDEPMQVHSKKRLKPLIPALRQKLKRSNPFNESQKKN--QDSSDPLPSPSVINTQ----
SKNISSSATQVS--CDQPLLKEGHKSAQKRAPQ-GEPTTVSEYFFNDIFIEVDETE----
-----

MFRRARLSVKPNVRPGAGAR------ASTA---PNSQREQEAPRPQEP--AAASAPKPPE
S----TDVPPVDFGEAEPQDKTPKS-S--VEKTDDGKD-VEESSKPSFTVSQKRKRIPST
SSLVKPSVSVPSEPHPLS------------------------------------------
---------------------------------------------------TVN-QEAPQ
PNPVPTKEKQPCSDRYRIYKAQKLREMLKEELRKEK--KQWKNKYAVNETQRPPDRSKMT
MRDFIYY-LPESNPMTSSLEQEKKTEKSSTPVRTREQ-ESKTTPDGEDND----EVEEEL
DEGPLLVPRVKVAEDGSIILDEESLTVEVLRTKGPCVVEENDPIFERGST--TTYSSFRK
SYY-SKPWSNKETDMFFLAISMVGTDFSMIGQLFPHRARIEIKNKFKREEKTNGWRIDKA
FQEKRPFDFDFFAHLLQKVLAEEEKRKQKSVKNQSSKEKKSSKSRKNV-KVKKVAND---
-DRDE----SVSTKISNSGRSQKDAQTVEEELQ-SLTLSEQDSEQNAL--DVNQKKRR--
--RKNQGEGSEQEV-HLSGSATVQPGSSKGEK-HKNKGLSLS----PEINENESSKEQEL
PCVQDTDDLVGL------SSSEDAEK---------RTDPILSS-SQQDVI----------
--S-VAT-ETAESNTSDLPSSEGGVRALC-------------EVNSA-ESSCTEERDVDL
KDKSLEPDQTETIKPMTRGRLQRPKPNLSRAVGKKSVLSRGKTDAEDKSL--HKETPVEK
SPMEKD-----GISGMENTEK-GN-REPDTVSN------LSEKTCLQEDDQPKA------
--FRPARLMRGLLQRPKPNVGKAAERKGTLTSQEKPGASIEKNENESCINRN-------T
PEQIEDQSCKNFECEDIAS-----LPEKKD---SSFQNVQSDEPKAVNECLSIQEDNRA-
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------NKDVRIPKTRFQKPKPNIGRRTGRRGISSKE-----EVPKEVIASEEM--
---TAALRET----------ATL-ETSLREKEPVET-------NTTKEMESD--------
-LKEIGRKDISSRD--IMPEMSDVAVEMETDLKETEKNDISLREKM-PEISDVTVEMKTD
LKETEKNDISPMEKIPEMIAVIAEMETDLKETEKNDISPREKIPEMSDVTT---------
------------------------------------------------------------
-------------------DLKETGKNDISPRETEIPEMSDVTVEMKTDLKEVGTNDIPP
REKMPEMIDVTAEMGTDLKETGKNDISPREEIPEMSD-VTVEMKTDLKEVGTNDIPPREK
MPEMIDVTAEMGTDLKETGKNDISPREEIPEMIGVSVELE--------------------
-------TDSRETGKNDISAREKMPEM------------------------------SDA
TEERKTDLEETERREMSLEENVPEEVDSICEVETDL--------KKTEREISPNEEIAEM
--PDAAEEVETGLEETDRR--------------------------------------EIS
TQKNA--SEVKTVGDEMDIDLKEIGIEI------SPRD----------------------
--------KILLGISATGERETDVEETGQTDI-FLMEKASAKVAATEEIEADLRDTGKEI
SV---T----KSRSEEI---EK---SVADL-KNVEKIDISL-REK-----EPEE---TGT
SSR-AEADPLQASSGDS-----STVPSLTER------------------------VCIFL
EVLSAVVHTSVEE-KNSEKEVSSQLSHLNISSQSS-ELDKIEDQRKRPPSV----PE-QF
SDV---------------------------------------------------------
-----------------------------------------------------------N
ISKSLPQEQ-----------------TPCEVKLTPFVRSRFKRPKPNLARAASKRETTKA
EKHAPGK---------EV------------------------------------------
---------EADETETVVIQQNCEQMSTLPSQLD-VAS--------LMTSREKDKLD-HG
PEETVILPCVQTEKDLSP--LSSCESKEESQSTQAQ--EKKLVVSMGTHN-INTFEQGIK
ERVIQSAPLVRGRLQRPRPNLRKVGQRQVI---EKSETK--ETTK-E-------------
-----------EKTLQK-DETGEK-FLTVP-----NSQIATEIE-VVSSEVSEGRMS---
------------ENQ-------SHVLL--ENVHINKVDILDEKMRHG-HETYVPSPPQMI
GRQFQRAKPNLGRAQSKK-EASDVEEDRADQ--RKARKPEDS-LSQHEGSDS--RLLPKG
KP---EFLTSLEVSARKDS-VGSEETELAKKDAQS-EVEPSGSVGE----K-----TG-E
DNSVCAVVE-------------------------------------------------N-
-----SPQLLKEPDNSK-----------------IALDRRRALSSAS----EREIDHSR-
RRVRR-KVK---PSIPKGRGSKRSRSKTSKKEPRASR---SVLVTLRASQEADE--DDGE
DFESDYEEESYHLAPEEVN---KAPVFVPIGLRSPEPVPVQIEETMEE------------
-----------------------LVIPTNVTDVGCITVVEHQLSSNVDVIPQEMRQEENL
NAVSVVSIH-------FIIANDGSTEAAITLLTMGDLVLQSEIGPEQSD--GICILPDAH
SIDQSHIPFSSDNVNLKIVHDCQEP-SSPG-HDTSPS-VEQNKIVLDVDKQNTKEEIGLT
-EVKENTTSSRTTTSEV--TNNVRKRSRFAKPKPNLKKILGTKRFGAHQKVPSLFVTKGE
EVEIQRE-TEKNASQE-----------------TELEDKNLGSVTATESTEQ-SKVASAH
GVEETSIS-QEAHLTERGEDQEGRSEEVPISSVAPAVSS-ES-------------GPHTG
GLGMGLGESSVEEPLGKDFNGDPVLTLNVPE----CI-PTS-IPEVQQENVND-L----Q
DITVNLV-NVHQD-GEDEQTFILTLVEIP----EEYADSTM--QLMPNPLLPAPILVKSM
NTKE-REDTSIS---FPVTSVGQDHMCLSNS---------ERDDS-EKSAANLTLVSRKR
YHCSVDESDH--VPPAKKTSL-------TSIDDSYVL----------TIFFFFEGESYKG
Q-------DIFPTSGNIQ-TISEPQKEELEPT-SQS---IRSG-SL-DKITDTQ-EKDAS
QLPQDEM---MVSGKEERTCAASESEQMGSITSSSKPPLTRPGRRPLGFLSLLCSKNS-L
DSDEPTQVHSKKRLKPVIPVSRQNLKRCNLPSVSQKKT--QESSD-VPSPSVVDNTQ---
HTNNASSATQVS--HNRPLLKGECKGGQNRVPE-EEPTTVSEYFFNDIFIEVDETE----
-----

------------------------------------------------------------
------------------------------------------------MPTQRRKRISTM
PNLVKPRAGPSSGLHTASKPQR--RASQAPDGSASLQKDSPPSEKSHAESSSKSPMLPEK
KTPVPQVPQFSPLKKSMNKEQTVAAQ--R-NDDTLKSVPSPLKERPTQETSVAQ-EEKLP
PKPSPVKEKRICSDRERILKARKLREMLKEELKKER-MKQLKHRPPIIEGCSPPDRSKMT
MRDLIYY-LPENNPMKSSLAEEKRTEKSSALGQTKE-QEEKSTPDHEEEDEEEAENGEES
QDGPLLVPRVKVAEDGSIILDEESLTVEVLRTKGPCVVEENDPIFERGST--TTYSSFRK
SFY-TKPWSNKETDMFFLAISMVGTDFSLIGRLFPHRARAEIKNKFKREEKANGWRIDKA
FKEKRPFDFELFAQLLEKVLADEEKRRQKTVKSQKPKEKKPLRPRKKP-KG-KVANTETT
DNQDD----LQEARISDAET-EADTVTAEKENKESLGVSEEAEEQVSLEATLVNKKRK--
--RKRKGDL-EQEVENRPEELAVTSKIPEEGKSSK-KTGKKMANDTNAAGHTLCREELGS
VIEEEQDDLHAKEQER-----SLSFISMD---DITERESDVNLCSFQDSSDKLVTEPTKL
QSLDVTGDTSQESQFSECPVSQTRSKERQLEEARET------TCADT-HGLHEPEEKQNA
SERDSQSQIMKTEKPAERRRLQKPKPNIMKLPGKKEAVNHEKMEAETSSP--NLVNITEK
CSEE-----NSEGNRSEITEV-ES-MDLDTKSEGPE-KTVS-------------------
----AVARIRGSRQRFKPNLTRASGR------------KEHE-NN-SENDKM-------S
QPESKEETEKNTDQSRKFDVTDGEAAEKDD---KVSE-----MVSQSNETTGSQEGSKQ-
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------SVLKPAPLKRGRVQKPKPNLGRTVAWKKDHSHE-----KDPEEEKVEGGEAE
GHVVHHVNEGNDSCHKNDMVGAP-KKSPQK------------------------------
------LKDVE-----NEKGSSDVLKDV---SDFNTG-ESGPGNQEDKTVIS-----SVR
LLRSRFHRPKP-------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------NLRT
TS-RKEVTDINKG-VSQED-TNKKESSMQSTDEC-CVLLDTDK-------AENC------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------EVLQS-----------
--LESLGKEKSVGPQDVSESSSFK-SPD---TLPRSED-----------GKVEPCLLVDN
Q-------------NETSSTNAGIDREIT-----TQGE--SKQTPLQPVQLVRSG-FQKY
KPNL----GKGVRRKELQ-----IPEDNEDKK-SE-------------------A--DEL
EV---QK-------TE---SVH---HVSAI-GKKEA------------------------
-AL-HEENVLSNEEP---------------------------------------------
-----------------------------------------------AQE------E-VP
QMP---------------------------------------------------------
-----------------------------------------------------------C
ISGNLLCEQI--------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------RS---NE-KLSSGEESN
QCDTKPSQQARVSLRNPKPNLTRAHRKRSH---SED-R----NRR-D-------------
-----------KDNAETRN---TE-EHLLE-----K----------------TG---VS-
--------------V-K-----NSS-------NTEEAASFTESTGKHDSTDSVERPSRKR
IRKI-------SSSF----QSPEVP----L-------ESESQ-VEQE-DSQL--SAPQQK
------------------------------------KSDDQT------------------
-----------------------------------------------------R--RQ--
-----SRRLSKQITLPK-----------------HGLELRTGSSSAP----ECEADCCE-
KGNQRQEVK---SSVIRGKSMKTAHRKKPVKEQRSSK---TSSLVTLRASQEDE--EEAD
DFE--PDDDDECFALEEVN---KAPVFVPVGLRSPKPIPVQIEETMEE------------
-----------------------LDISVNIPDVPVATNVEGPS--YVSV-QPAIQKEKGN
TL-PAELTVHENPELD-KGISDGSTEAAMTLLAMGDPTFQLKANTE----EWTRMLPAQD
EVNIANSLVSHD-DSEQNIAPNQYVVSSATSAK--VPCKDGSNINVE--DRSTCAGTGVE
EYFEKDATDARNSSLPM-VNSMTLRRGSLQKSNPNTGV-LKSNE-SVIQNPLNTNVVMEQ
LDSIQSE-SMD---SR-----------------GTTEAQKVEQVSVGPTLRDTSVLQDFA
T-SVELVK-QI----DNKGRTQEEMKDV-------------CGTSGNL-------SPGCE
KSHLGLEDYLDEGSVDRTAVQNPCPAKDSQCTLGFAQNETH-AQDCAQQHISS-T----E
ETSV-NNY-PRCP-EEEEQTFILTLVEILANSEEFDTSALQ--EQTSEPLLPAPILISPV
KSSG-TSLTEV----ESIGSLTTAADELGEYSNSGTETKQQESASVESVLTLVHT-AQKR
SAAEPAENDV----PLVKKTVST-VVESNVEGPCQGYS-----SKSTNTQTRTSDDPFQK
TGVSAKENILASALLS---ISPVDERSQC-ET-LEN---SGKA-SF-HNLASSQEEEMTC
GLTSSTETEISEQGKLGDKHEAAQLECTESLTESSKTPLLS-------------RKSS-S
ESAEEVQRKREKIPNPQTGTTKPSLKNT---TPSSKDD--KES-CSFPSTSTSSFVE-Y-
-DSVPADAVVVAPHNEPSEKPPHCAGD--QEKE-EEPTKISEYFFSDIFMEVDDPE----
-----

------------------------------------------------------------
------------------------------EKSNSSSD-AGEAGKPTDMPTQRRKRISTM
PNLVKPRAGPSSDLHTASKPQ---------------------------------------
-------------------------------------------------------REKLP
PKPSPVKEKRICSDRERILKARKLREMLKEELKKER-MNSR-HKYSYTVTQNPLKYPKDS
YQDNIWYVVPSSDMIKRIETEEKRTEKSPALHQMKE-QEEKSTPDHEEEDEEEAENGEES
QDGPLLVPRVKVAEDGSIILDEESLTVEVLRTKGSCVVEENDPIFERGST--TTYSSFRK
SFY-TKPWSNKETDMFFLAISMVGTDFSLIGRLFPHRARAEIKNKFKREEKANGWRIDKA
FKEKRPFDFELFTQLLEKVLADEEKRRQKTVKSQKPKEKKPLRPRKKP-K----------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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-----

MFRRARLSVKPNVRPGAGAR------TSTA---PNPQRGQEAPRPPEP--AVASSSKPAE
P----PDVPSVDFGGAEPQEEAPRR-S--DEKTDGEND-VGESNKSSSTVSQRRKRISST
STVVKPSVSVPSEPHPLS------------------------------------------
---------------------------------------------------TVN-QEDSQ
PNPIPTKEKQPCSDRYRIYKAQKLREMLKEELRKEK--KQWKNKYAINESQRPPDRSKMT
MRDFIYY-LPDSNPMISSLEQEKKTEKSLTPIQMRXXXXXXXXXXXXXXX----XXX--X
XXXXXXXXXXXXXXXXXXXXXXXXLTVEVLRTKGPCVVEENDPIFERGST--TTYSSFRK
NYY-SKPWSNKETDMFFLAISMVGTDFSMIGQLFPHRARIEIKNKFKREEKTNGWRIDKA
FXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXKKVASEGVS
DDPDE----SMSAKISDTEETQKDAQTVRQ--Q-SLTLSGQDSEQIALEPDLTQKKRR--
--RKNQDEAGKQEVKNVPGNAIVQPGASKGEK-QKNKCQSSR----PEINKDEGNKEQKL
SCVQNIDDIEDL------SSSDEVEE---------KTDPILSSSSQSDAM----------
--S-VAT-EISESSTSDLHSLEVGIRALC-------------EVNNA-ETSCTEERTVDL
KTKSLXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXX-XXXXXXXXX
THMEKDKVNTFDVSGMENTQR-EN-SEADSVSN------LSEKICLQEDDQPKA------
--FRPARLMRGRFQRPKPNVGKAAERREILTSQEESGANVEKNENEFY-----------T
PEQIEDQSCKNFECGDITS-----QSEKKD---TFFQNVQLDEPKALNECLRAGNSSPK-
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------RRKLLV---------EANIEMVQK--------
-FKETGRRDIFPEK--VL---EDVTVEMETDLKETGR-EISPREKI-LEMSYATEEREAY
LEEPRRKEISPQNNAPEEVNTVSDLEIDKE------------------------------
----------------------------TRR-----------------------------
--------------------------------------------------------GISP
RETISQVTNATEERETDLEETR-REISLQKNAPEEVN-TVGDLELGLKETGR--------
------------------------------------------------------------
--------------------------------------------EVSPRE--KLPEVTDA
TEERETNLEET-RREISLQKNASVGVNTVGDLELGL--------KETGREVSPREKITEV
--TDITEEREANLEETERR--------------------------------------KIS
TQEKA--PEV-KTISKTETDLKKIEKEI------SLRE----------------------
--------KVLVEICAMGESEINLKEIGKRDI-SLMEKVSGKMTVIEETKADLKETGRKI
SL--------KSGSEEMNVTEK---MVADL-KNTGKHDISL-REN-----EPKE---TET
SRQ-TMTDLMQSSSGDC-----STMPSLNAK-------------------------NISS
EGLSMV-HTFVEEKRNSEKEVSGQLSRLKTS-----EHDKTEDQGTRSPDV----PE-QF
SDV---------------------------------------------------------
-----------------------------------------------------------N
LSRCLPQEQ-----------------KPFEVKPAPFVRSRLKRPKPNLSRAALKRETVEA
EKYVPGK---------KL------------------------------------------
---------EMDKTETIVIQQDDEQMNTLPSQHSAVAS--------LMTSREEDKSG-HR
QKEAVILSCVQTEKDLSP--SSSCESKEESQSTQIQ--EKELVVSMGTPN-VHTFQQEMK
ESVIQTARPVRGRLQRPRPNIRKAGQRQIV---EKGETK--GIIK-K-------------
-----------ERTILQKDETKKK-FLTEP---------GTEIE-VIFSKGSEGRMY---
------------ENQ-S-----DAVLI--EDLHVNKINVLDEKMRHE-HKMCVPSPAQF-
QRQFQKADPNLRRAHGKK-AESGIEKDGIDQ--SEARKPEDT-LLQKEDSDT--QLLHKE
KD---DLLTSTEVSARKDF-VGSKEPGLAKKGAQS-EVGPSASVGQ----K-----TV-G
DNSVSSVAEEQ--------------------------------------YLSKL---AS-
-----CTQLLKESHYSK-----------------IALSRRTAISSAP----GCEIDHSE-
RRMYR-KIK---PNVTKGRGSKRIRSKTSKKEPRASK---AILVTLRASQEEDE--DDAE
DFESDYEEESYHLAPEEVN---KAPVFVPVGLRSPEPVSAQIEETMEE------------
-----------------------LEITVNVPDIGFITVDEHQFL-NTDVTTQEMKQEENL
NALSVEMTTGEHTHDE-TGPNDGSTEAAITLLTMGDLVLQSEISSEQSD-VAVCVFPDVP
SEDKSHIPFSPDDVNYKIVHEGQEL-SSLD-SSTSPS-SEENKIVLE--EQSTKEEIGLM
EKVKGNTVSTRNTTCEV--TNNLG--NRFAKPKPNLRKILETNSFDAHQEVPSLFVTKEE
-VEIQRE-TK-NASET-----------------TELEDKNPGSVTTAENTER-SRLAYVH
GIEETCISLQEASLTERKKDQERGSQEVQILSVAPTVSS-ET-------------RPHTL
GLGTGLGESSVGEPLRKDSNGDDVLTLYVPE----CT-SAS-IPEVQQENVIN-P----Q
DLTVNLVANVHHD-GEDEQAFILTLVEIPTNAVEEFTDTVT--QLIPNPLLPAPILVKSV
NTEE-KGDMSMN---FPVTSVGPDATCLSNS---------GRDDS-EKPPANLXXXXXXX
XXXXXXXXXX--XXXXXXXXX-------XXXXXXXXXXXXVCSRELIKVFEE-RGKSYKG
Q-------DIFPTSESTH-TTSEPQKEQLEPI-LQS---TGSK-SL-DKIIDTHIEKNTP
QLPQDEM---IVSDKEERTCAASKVEQMDSVTSSSKTPLSRPGRRPLGFLSLICSKNT-L
ESDEPIPVHSKKRLRPLLPVSRQNLKRSGLLNASHKKF--QESSDLLPSPNVVNTH----
AENID-SSAQVS--CDCSLPKEECRSVQNQVLE-EEPTTVSEYFFSDIFIEVDETK----
-----

MFRRARLSVKPNVRPSVGAR------GSTA---PNPQRGQESPRPPEP--ATDTASKPAE
P----TDVPAVDFGGAEPQEKAPRS-S--SEKTGSDND-VEESSRSSPTVSQRRKRISST
SSLVKASVSVPSESHPLS------------------------------------------
---------------------------------------------------TVN-QEAAQ
PTATSTKEKQPCSDRYRIYKAQKLREMLKEELRKEK--KQWKNKFAINESQRPPDRSKMT
MRDFIYY-LPDNNPMTSSLEQEKKTEKSSTPVQTREQ-EGKSTANAEDN-----EMEEET
DDGPLLVPRVKVAEDGSIILDEESLTVEVLRTKGPCVVEENDPIFERGST--TTYSSFRK
NYY-SKPWSNKETDMFFLAISMVGTDFSMIGQLFPHRARIEIKNKFKREEKTNGWRIDKA
FQEKRPFDFDFFAHLLQKVLAEEEKRKQKSVKNHSLKEKKSTKPRKNV-KVKKIACERVN
DDPDE----SMSSRISDTERSQKDAQTVDEE---SLTLSGKDAEQVALEVDLNQKKRR--
--RKKQDGANELEVNNLLENATVQAGPSKGEK-HKNKCQAIR----PEVKEGECSKEQML
SCTQNVDGIVGF------ASSEKVEK---------RTDPILSLSNQQDAA----------
--S-VAT-ESSESSTSDLPSLEVGIRASC-------------EVNDA-ESSCTEERNVDL
KNNSLEIDQTENVKPMLRGRFQKPKPNLSRA-GKKSVLSQGKTEAESKN--SHSKTSVEK
DHLEKDKMNTLDILRMETTER-EN-PEAETVSM------LGEKNCLQEESQLKA------
--LTPAKV-RGRLQKPKPNVGKAAGRKEILMSQEEIGANVEKNENESRADRD-------T
-QRMEDQSCKDFEEEDVIL-----QPEKND----SFQNVQPDEPKVLNECLSIQENNKA-
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------NKLNQVPILRTRFQKPKPNIGRGTGRREISSKE-----EVLEKILASGEM--
---TAALRET----------VRL-DTSPKEMVPAEI-------NTTKEMQSD--------
-LKETGRRAISPRE--KILDVIDVTREVETGLKARGR-EICLREKT-PQVIDATKEIDKD
LEETGRREIPPHENGPEEVKPVGEMETNLKATGN-ESSPREKTP----------------
----------------------------------------EVVDATQEIDKDLEDTGKRK
ISPKENGPEEVKPVD-----------------------------EMETDLKATGR-ESSP
REKTPEVIDATEEIEIDLEETER-EISPQENGPEEVK-PLGEMETDLKAAGR--------
---------------------ESSPREKTPEVTDTTEEI---------------------
-------EIDLEETEREISPQENGLEVVKPVGEMETDLKAT-GREISPRE--KTPEVIDA
TEEVDKDLEETGRREISPEENSPEEVKPVDEMETDL--------KATGRESFPREKTPEV
--IDAAEEIEIDVEETE-R--------------------------------------EIA
PQESG--PEVVRPVGKMETDLKEIREEI------SQRE----------------------
--------KVLAEISAVREKEIDLKEAGKRDI-SMMEKVSGKMAVIEEMETDMKETGRE-
NF---R----EKESEEICVTEE---KVAEL-KKTGKTDISL-REN-----ELEE---TST
SRQ-TETHLMQSGSNDC-----SAMPSLDIK-------------------------NISS
EVLLMM-HTPVEEKRDSEKEVSSPFSHFKISSQTL-ESDKTEVLGIRSSDV----PE-PF
SDI---------------------------------------------------------
-----------------------------------------------------------N
LSRSLPQEQ-----------------KSLEIKPAPFVRSRFKRPKPNLARAALKRETTAS
EKYIYGK---------KS------------------------------------------
---------ETKKMETIVMQENNEQADTLPSQHD-EAS--------LMISREKDTSG-HR
NEEAVILPCTQTEENLST--SNSCEPKEESQSAQAQ--ENDLVVSVGTNN-INTFQQEMK
ESVIQTARPVRGRLQRPRPNVKKTGQRQIV---DKGNAK--GIIK-E-------------
-----------ERTVLQKDETEKK-ILTAS-----NPQIETDIE-VPSSTVSEHRMC---
------------ENQ-S-----QVILV--ENLHINKT---DETIRHE-NKLYVPSSAQMT
RRKFQKAKPNLGRAHSKK-EEPILEKGTTDQ--SKEGKPEDH-LLQKGASNT--QLLLKE
KA---ELLTSM--AARKDC-VGSNESALAKIDAELEEAGPSRRVGE----E-----TV-G
DNSLSSVVEEQ--------------------------------------YLNKL---TS-
-----CPQPLKESNYSK-----------------IALDGKTTISSAS----EYERNRGE-
RRSHR-KIK---PNVTRGRGSKRVRGKTSKKEPRASK---AILVTLRASQEEE---DDAD
DFESDYEEESCHLAPEEVN---KAPVFVPVGLRSPEPVSAQIEETMEE------------
-----------------------LEITVNVPDVGCIAVVEHELP-NTDVTTEEMKQEENL
NASSFEMTTGEHIQDE-PGTSDGSTEAAITLLTMGDLVLQSEISTEQGD-VGVCILPHVH
SRDKSHIPFSLDNVNHKIVHECQEL-SSPV-ITTSPASFEENKIVLE--EQSSREEISLM
EKVKENATPTRNTISKV--TSNLRIRSRLAKPKPNLEKTLGTNRFDDHQEISSLCVTKGE
EMETQRE-TEKNASKA-----------------TELENKNLGPVTTAENKDQ-SKLACVH
GIKGTSIS-PEVNLTERNENQEESSQEVHMLSVAPVASS-ET-------------GPCTL
GLDRGLGENSVEEAQIKDSKGDSVLILPVPE-----YTPTS-IPEVQQ-ENIINP----Q
DLTVNLVANVPQD-GEDEQAFILTLVEIPTNAVEEFTDATA--QFMPNPLLPAPILVKSV
NTEE-RGDMSIC---LPATSVGQDAVGLSIS---------GRDNS-KKPLDNLDLISRKR
FKCRLDENDH--IPPAKKCSL-------TLRDDCQEYTSEVHSKELTNVFEE-TGESHKG
Q-------DIFPTSGSTL-TTPEPQRQQVEPA-FQS---RGSR-SP-DA----CIDKNVP
QLPQDEM---IVSDKEERTDAAPKSEQMDNRTSSSKAPLSRPGRRPLGFLSLICSKNS-L
ESDEPMQVHSKKRLKPLIPALRQKLKRSNPFNESQKKN--QDSSDPLPSPSVINTQ----
SKNISSSATQVS--CDQPLLKEGHKSAQKRAPQ-GEPTTVSEYFFNDIFIEVDETE----
-----

MFRRARLSVKPNVRPSVGAR------GSTA---LNPQRGQESPRPPEP--ATDSASKPAE
P----TDVPAVDFGGAEPQEKAPRS-S--SEKTGSDND-VEESSRSSPAVSQRRKRISST
SSLVKASVSVPSESHPLS------------------------------------------
---------------------------------------------------TVN-QEAAQ
PTATSTKEKQPCSDRYRIYKAQKLREMLKEELRKEK--KQWKNKFAINESQRPPDRSKMT
MRDFIYY-LPDNNPMTSSLEQEKKTEKSSTPVQTREQ-EGKSTANAEDN-----EMEEET
DDGPLLVPRVKVAEDGSIILDEESLTVEVLRTKGPCVVEENDPIFERGST--TTYSSFRK
NYY-SKPWSNKETDMFFLAISMVGTDFSMIGQLFPHRARIEIKNKFKREEKTNGWRIDKA
FQEKRPFDFDFFAHLLQKVLAEEEKRKQKSVKNHSLKEKKSTKPRKNV-KVKKIACERVN
DDPDE----STSSRISDTERSQKDAQTVDEE---SLTLSGKDAEQVALEVDLNQKKRR--
--RKKQDGANELEVNNLLENATVQAGPSKGEK-HKNKCQAIR----PEVKEGECSKEQML
SCTQNVDGIVGF------ASSEKVEK---------RTDPILSLSNQQDAA----------
--S-VAT-ESSESSTSDLPSLEVGIRASC-------------EVNDA-EGSCTEERNVDL
KNNSLEIDQTENVKPMLRGRFQKPKPNLSRA-GKKSVLSQGKTEAESKN--SHSETSVEK
DHLEKDKMNTLDILRMETTER-EN-PEAETVSM------LGEKNCLQEESQLKA------
--LTPAKV-RGRLQKPKPNVGKAAGRKEIHMSQEEIGANVEKNENESRADRD-------T
-QRMEDQSCKDFEEEDVIL-----QPEKND----SFQNVQPDEPKVLNECLSIQENNKA-
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------NKLNQVPILRTRFQKPKPNIGRGTGRREISSKE-----EVLEKILASGEM--
---TAALRET----------VRL-DTSPKEMVPAEI-------NTTKEMQLD--------
-LKETGRRAISPRE--KILDVIDVTREVETGLKARGR-EICLREKT-PEVIDATKEIDKD
LEETGRREIPPHENGPEEVKPVGEMETNLKATGN-ESSPREKTP----------------
----------------------------------------EVIDATQEIDKDLEDTGKRK
ISPKENGPEEVKPVD-----------------------------EMETDLKATGR-ESSP
REKTPEVIDATEEIEIDLEETER-EISPQENGPEEVK-PLGEMETDLKAAGR--------
---------------------ESSPREKTPEVTDTTEEI---------------------
-------EIDLEETEREISPQENGLEEVKPVGEMETDLKAT-GREISPRE--KTPEVIDA
TEEIDKDLEETGRREISPEENSPEEVKPVDEMETDL--------KATGRESFPREKIPEV
--IDAAEEIEIDVEETE-R--------------------------------------EIA
PQESG--PEEVRPVGKMETDLKEIREEI------SQRE----------------------
--------KVLAEISAVREKEIDLKETGKRDI-SMMEKVSGKMAVIEEMETDMKETGRE-
NF---R----ERGSEEICVTEE---KVAEL-KKTGKTDISL-REN-----ELEE---TST
SRQ-TETHLMQSGSNDC-----SAMPSLDIK-------------------------NISS
EVLLMM-HTPVEEKRDSEKEVSSPFSHFKISSQTL-ESDKTEVLGIRSPDV----PE-PF
SDI---------------------------------------------------------
-----------------------------------------------------------N
L-RSLPQEQ-----------------KSLEIKPAPFVRSRFKRPKPNLARAALKRETTES
EKYLYGK---------KS------------------------------------------
---------ETKKMETIVMQENNEQADTLPSQHD-EAS--------LMISREKDTSG-HR
NEEAVILPCTQTEKNLSP--SNSCEPKEESQSAQAQ--ENDLVVSVGTNN-INTFQQEMK
ESVIQTARPVRGRLQRPRPNVRKTGQRQIV---DKGDAK--GIIK-E-------------
-----------ERTILQKDETEKK-ILTAS-----NPQIETDIE-VPSSTVSEHRMC---
------------ENQ-S-----QVILV--ENLHINKT---DEKIRHE-NKLYVPSSAQMT
RRKFQKAKPNLGRAHSKK-EEPILEKGTTDQ--SKEGKPEDH-LLQKGASNT--QLLLKE
KA---ELLTSMEVSARKDC-VGSNESALAKIDAELEEAGPSRRVGE----E-----TV-G
DNSLSSVVEEQ--------------------------------------YLNKL---TS-
-----CPQLLKESNYSK-----------------IALDGKTTISSAS----EYERNRGE-
RRSHR-KIK---PNVTRGRGSKRVRGKTSKKEPRASK---AILVTLRASQEEE---DDAD
DFESDYEEESCHLAPEEVN---KAPVFVPVGLRSPEPVSAQIEETMEE------------
-----------------------LEITVNVPDVGCIAVVEHELP-NTDVTTEEMKQEENL
NASSFEMTTGEHIQDE-PGTSDGSTEAAITLLTMGDLVLQSEISTEQGD-VGVCILPHVH
SKDKSHIPFSLDNVNHKIVHECQEL-SSPV-ITTSPASFEENKIVLE--EQSSREEISLM
EKVKENATPTRNTISKV--TSNLRIRSRLAKPKPNLEKTLGTNRFDDHQEISSLCVTKEE
EMETQRE-TEKNASKA-----------------TELENKYLGPVTTAENKDQ-SKLACVP
GIKGTSIS-PEVNLTERNENQEESSQEVHMLSVAPVASS-ET-------------GPCTL
GLDRGLGENSVEEAQIKDSKGDSVLILPVPE----QYTPTS-IPEVQQ-ENIINP----Q
DLTVNLVANVPQD-GEDEQAFILTLVEIPTNAVEEFTDATA--QFMPNPLLPAPILVKSV
NTEE-RGDMSIC---LPATSVGQDAVGLSIS---------GRDNS-KKPLDNLDLISRKR
FKCRLDENDH--IPPAKKCLL-------TLRDDCQEYTSEVHSKELTNVFEE-TGESHKG
Q-------DIFPTSGSTL-TTPEPQRQQVEPA-FQS---RGSR-SP-DA----CIDKNVP
QLPQDEM---IVSDKEERTDAAPKSEQMDNRTSSSKAPLSRPGRRPLGFLSLICSKNS-L
ESDEPMQVHSKKRLKPLIPALRQKLKRSNPFNESQKKN--QDSSDPLPSPSVINTQ----
SKNISSSATQVS--CDQPLLKEGHKSAQKRAPQ-GEPTTVSEYFFNDIFIEVDETE----
-----

MFRRARLSVKPNVRPGVGAR------GTAA---PSAQRAREPARPCKP--AAEAAPKPAE
P----ADAPPADARAAESPQKAPGS-S--DEKTGGENN-VEKFSKSPPPASQRRKRVSST
SSLPKPSVSVPVQSHPSS------------------------------------------
---------------------------------------------------PVS-QDAPQ
PNLLPPKEKPPCSDRYRIYKAQKLREMLKEELRKEK--KQWKNKYAINESQRPPDRSKMT
MRDFIYY-LPDNNPMTSSVEQERKTEKSLTPTHRQES-KISPDADVNPND----EVEVEE
EDGPLLVPRVKVAEDGSIILDEESLTVEVLRTKGPCVVEENDPIFERGST--TTYSSFRK
NYY-SKPWSNKETDMFFLAISMVGTDFSMIGQLFPHRGRIEIKNKFKREEKTNGWRIDKA
FQEKRPFDFDFFAHLLQKVLAEEEKRKQKSTKTQNLKEKNSSKPRRNI-KAKKVASEAVG
DHPDE----SVSTDISDPEQSPNDPQTVEEE-E-SLISSGQGSEQVVLEQAQSQKTRR--
--RKCQHEANKQDDKNLTENATVLSGSSEAEI-LESKCQ-------PEANESVCNKEQNI
-----DDTIVDL------VSSEKSEE---------RIDPDSLACDQQGTP----------
--P-VAT--ELESSASDFPVSEAGIAASC-------------EVSST-ESNCTEESPVDV
KSKQLESDKTENNKPTLRSRLLRPKPNLSRAVGKKLVASQGKMDGESKN--SCSETSVQK
DLMENDKMNISDSFAVENTEK-EN-PEAECILK------LSEKSCQQEDSQPKI------
--CRPVRLMKTRMQRPKPNVDKAIERREILSSQETVGGNEIR-EKQSCDDKD-------V
--------------MDTS------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------PQE--------------NIPKLESD--------
-IKETGKNDSFP-T--KMTEMTGISVEIEIGLKETGR-EGFPGKKT-PEVIDITLETERG
LQPSRNVS--P------GLQASGVVSPGLPASGNAS------------------------
------------------------------------------------------------
--------PGIQTSGNVSLGLPASGT--VSPGF---------------------------
------------------------------------Q-AYGSVSPGFQASGN--------
----------------------VSP-----------------------------------
--------------------------GLQVSGNTPPGLKTS-G-NASPRE--KIP---EL
IEKINTNLEETGKRELFPQENVRKDVISVSEVETDM--------QEIGKEMSTRERTSGM
--IGITEEKESDLGETEKK--------------------------------------EIA
TQLKY--PEEVKIV-EMETELKEIGEET------FPRE----------------------
--------KAPVDSSAIGEKEIDLKGTGERAI-SVMEGVSGKMTALEKTKGDLKEPGREI
SV---SW---ERRSEEICVREE---IVTDL-EKTGKAGISP-REH-----QPEE---HGT
SEQTVTSNIITEA-----------------------------------------------
---S-VVPPSVEEKESADKHASSAFSHANTASQNS-RLHDIGEQGVQSPAA----LE-QF
SDV---------------------------------------------------------
-----------------------------------------------------------N
LSKSLPQEQ-----------------KPLDVKPAPFVRSRFKRPKPNLARAVLKRETTEV
EKCVPEK---------KP------------------------------------------
---------EANEMETTMIQQGSEQASSLSSEND-VTS--------LMTSKENDKLG--D
KEEAVIVP----GKDPSS--SNSYESKEESLLFQNQ--EDDLVVSVGTQK-TNIISEGTK
ESVVQTALPIRGRLKRPRPNVQRARQRKTA---ETGETE--DIDK-E-------------
-----------ERPTLQKDETKDK-SLTGS-----NSQIEAEIE-VVSPRVSECRVN---
------------ENQ-S-----QVVSV--ENVPINKRNALDEEMRLE-NKPYVPSPAPLI
RRRFQKVKPNLGRASLKK-VQPGIEKDTSDQ--SEAQKPECD-LVQQGGSDD--QVLLKE
KA---GILTSVEIST-EDC-IDSNESGLAKKDAQL-KAESLGNTGE----G-----TQ-R
DNSMSSV-EEQ--------------------------------------HLNTE---TS-
-----HPQLLKESNYSK-----------------IAPHRRTALSPAS----ECEIDHSG-
KRMYR-KTK---PNVTKGRGSKRVRGKTAKKEPRAAK---SMLVTLRASQKEDE--DDAE
GFESDYEDETCHLAPEELS---KAPVFVPIGLRSPAPVSAQIEETMEE------------
-----------------------LEITVNVADEGCVTVVEHEFS-NTDV-TQDLKQENNL
QTLSFVSI--------------------------------------HFNVLGLCVFPDTR
SEDQSHIPLRTDNVNHKIAHEYQEL-SLPA-ISVSPTSFDENKIILK--EENTRQETGIM
EETKENNTPIRYAASTA--NTNLRMESEIVKPNPNSEKILGHIGFSAHQEVPNVCIAKGT
EVEIQRD-KN------------------------------LG--LTAESKEL-NHWTCVH
DIKGTSIS-QEANLMERNEDQEEKLQEVQILSVTPLDSP-ET-------------RFHML
GSG-NVGDSSVEEALKKNSNDDSELMLHVPE----VK-EST-IPEVQQENVIN-P----Q
DQTVNLFADLHQD-EEDEQAFILTLVEIPASAAGGFTDATV--QSVPSPLLPAPILVKSR
NKGE-RDDLSVS---LPSTSLVQDVMYLSNSN--S-----GGEDS-ENSHANLDFTSRKR
FPCRLDESDL--VPPAKKSSL-------MSRVGYQEFASEVRL-----------------
------------------------------------------------------------
-------------------------------------TQDVPGRRPLGFLSLICPKNS-L
DSDEATHVRSKKRLKPLIPVSRRNLKKLNLHNESPKKS--QESSDSLPSTSV--------
------------------------------------------------------------
-----

MFRRARLSVKPNVRPSVGAR------GSTA---PNPQRGQESPRPPEP--ATDSASKPAE
P----TDVPAVDFGGAELQEKAPRR-S--SEKTGSDND-VEESSRSSPTVSQRRKRISST
SSLVKASVSVPSESHPLS------------------------------------------
---------------------------------------------------TVN-QEAAQ
PTATPTKEKQPCSDRYRIYKAQKLREMLKEELRKEK--KQWKNKYAINESQRPPDRSKMT
MRDFIYY-LPDNNPMTSSLEQEKKTEKPSTPVQTREQ-EGKSTANAEDN-----EMEEET
DDGPLLVPRVKVAEDGSIILDEESLTVEVLRTKGPCVVEENDPIFERGST--TTYSSFRK
NYY-SKPWSNKETDMFFLAISMVGTDFSMIGQLFPHRARIEIKNKFKREEKTNGWRIDKA
FQEKRPFDFDFFAHLLQKVLAEEEKRKQKSVKNHSLKEKKSTKPRKNV-KVKKIACERVN
DDPDE----SMSSRISDTERSQKDAQTVDEE---SLTLSGKDAEQVALEVDLNQKKRR--
--RKKQDGVNELEVNNLLENASVQAGPSKGEK-HKNKCQAIR----PEVKEGECSKEQML
SCTQNVDGIVGF------ASSEKVEK---------RTDPILSLSNEQDAA----------
--S-VAT-ESSESSTSDLPSLEVGIRASC-------------EVNDA-EGSCTEERNVDL
KNNSQEIDQTENVKPMLRGCFQRPKPNLSRA-GKKSVLSQDKTEAESKN--SHSKTSVEK
DHLEKDKMNTLDILRMETTER-EN-PEAETVSM------LGEKNCLQEESQLKA------
--LTPAKV-RGRLQKPKPNVGKAAGRKEILMSQEEIGANVEKNENESRADRD-------T
-QHMEDQSCKDFEEEDVIL-----QPEKND----SFQNVQPDEPKVLNECLSIQENNKA-
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------NKLNQVPILRTRFQKPKPNIGRGTGRREISSKE-----EVLEKILASGEM--
---TAALRET----------VRL-DTSPKEMVPAEI-------NTTKEMQSD--------
-LKETGRRAISPRE--KILDVIDVTREVETGLKARGR-EICLREKT-PEVIDATKEIDKD
LEETGRREIPPHENGPEEVKPVGEMETNLKATGN-ESSPREKTP----------------
----------------------------------------EVIDATQEIDKDLEDTGKRK
ISPKENGPEEVKPVD-----------------------------EMETDLKATGR-ESSP
REKTPEVIDATEEIEIDLEETER-EISPQENGPEEIK-PLGEMETDLKAAGR--------
---------------------ESSPREKTPEVTDTTEEI---------------------
-------EIDLEETEREISPQENGLEEVKPVGKMETDLKAT-GREISPKE--KTPEVIDA
TEEIDKDLEETGRREISPEENGPEEVKPVDEMETDL--------KATGRESFPREKTPEV
--IDAAEEIEIDVEETE-R--------------------------------------EIA
PQESG--PEEVRPVGKMETDLKEIREEI------SQRE----------------------
--------KVLAEISAVREKEIDLKETGKRDI-SMMEKVSGKMAVIEEMGTDMKETGRE-
NF---R----ERGSEEICVTEE---KVAEL-KKTGKTHISP-REN-----ELEE---TST
SRQ-TETHLMQSGSNDC-----SAMPSLDIK-------------------------NISS
EVLLMM-HTPVEEKRDSEKEVSNPFSHFKISSQTL-ESDKTEVLGIRSPDV----PE-PF
SDI---------------------------------------------------------
-----------------------------------------------------------N
LSRSLPQEQ-----------------KSLEIKPAPFVRSRFKKPKPNLARAALKRETTES
EKYIYGK---------KS------------------------------------------
---------ETKKMETIVMQENNEQADTLPSQHD-EAS--------LMISREKDTSG-HR
NEEAVILPCTQTEKNLSP--SNSCEPKEESQSAQAQ--ENDLVVSVGTNN-INTFQQETK
ESVIQTARPVRGRLQRPRPNVRKTGQRQIV---DKGDAK--GIIK-E-------------
-----------ERTILQKDETEKK-ILTAS-----NPQIETDIE-VPSSTVSEHRMC---
------------ENQ-S-----QVILV--ENLHINKT---DETIRHE-NKLYVPSSAQMT
RRKFQKAKPNLGRAHSKK-EEPILEKSTTDQ--SKEGKPEDH-LLQKGASDT--QLLLKE
KA---ELLTSMEVSARKDC-VGSNESALAKIDAELEEAGPSRRVGE----E-----TV-G
DNSLSSVVEEQ--------------------------------------YLNKL---TS-
-----CPQPLKESNYSK-----------------IALDGKTTISSAS----EYERNRGE-
RRSHR-KIK---PNVTRGRGSKRVRGKTSKKEPRASK---AILVTLRASQEEE---DDAD
DFESDYEEESCHLAPEEVN---KAPVFVPVGLRSPEPVSAQIEETMEE------------
-----------------------LEITVNVPDVGCIAVVEHELP-NTDVTTEEMKQEENL
NASSFEMTTGEHIQDE-PGTSDGSTEAAITLLTMGDLVLQSEISTEQGD-VGVCILPHVH
SKDKSHIPFSLDNVNHKIVHECQEL-SSPV-ITTSPASFEENKIVLE--EQSSREEISLM
EKVKENATPTRNTISKV--TSNLRIRSRLAKPKPNLQKTLGTNRFDDHQEISSLCVTKGE
EMETQRE-TEKNASKA-----------------TELENKNVGPVTTAENKDQ-SKLACVH
GIKGTSIS-PEVNLTERNENQEESSQEVHMLSVAPVASS-ET-------------GPCTL
GLDRGLGENSVEEAQIKDSKGDSVLILPVPE-----YTPTS-IPEVQQ-ENIINP----Q
DLTVNLVANVPQD-GEDEQAFILTLVEIPTNAVEEFTDATA--QFMPNPLLPAPILVKSV
NTEE-RGDMSIC---LPATSVGQDAVGLSIS---------GRDNS-KKPPDNLDLISRKR
FKCRLDENDH--IPPAKKCLL-------TLRDDCQEYTSEVHSKELTNVFEE-TGESHKG
Q-------DIFPTSGSTL-TTPEPQRQQVEPA-FQS---RGSR-SP-DA----CIDKNVP
QLPQDEM---IVSDKEERTDAAPKSEQMDNRTSSSKAPLSRPGRRPLGFLSLICSKNS-L
ESDEPMQVHSKKRLKPLIPALRQKLKRSNPFNESQKKN--QDSSDPLPSPSVINTQ----
SKNISSSATQVS--CDQPLLKEGHKSAQKRAPQ-GEPTTVSEYFFNDIFIEVDETE----
-----

MFRRARLSVKPNVRPGVGTR---G------SAAPNPQRGPEAPRPPEP--ATESAPKPAE
PTD--AP--AVDSGGAEPQEQAPGSS---DEKTGDKNN-AAESSTLSSASSQRRKRVSST
SSLVQPPGSAPSQSRPL-------------------------------------------
--------------------------------------------------STAN-HDAPQ
PNPTPAKEKQPCSDRYRIYKARKLREMLKEELRKEK--KQWKNKFSTNESQGPPDRSKMT
MRDFIYY-LPDNNPMTSSVEQEKKPEKSLTPTPTRDRQENQSTQDANDNE----EVEEEV
DDGPLLVPRVKVAEDGSIILDEESLTVEVLRTKGPCVVEENDPIFERGST--TTYSSFRK
NYY-SKPWSNKETDMFFLAISMVGTDFSMIGQLFPHRARTEIKNKFKREEKTNGWRIDKA
FQEKRPFDFDFFAHLLQKVLAEEEKRKQKSTKCQSLKEKAS-KLRKNL-KAKTVTSEEVN
DDPDE----SINSNISDPERSQNDAETVNEEE--SPSSSGQHLEQAMLEQDQNQEK----
KRRRNQGEANKQEATNLLERVLVHSSPPEAEIHEN-T-------CPSEENESECNKEQIP
SFTQNIDDIAGL------ASSEETEMR---------MDPISSTCNQQD------------
--IMPLARESLESCAAALPVWEPGSTASA-------------DMANA-EISCSEERGADL
KTASPETEQTENVKPKSRSRLQRPKPNLARAVGKKPAVSQDRQDERSKNS--PSETAAEK
NHMEKEAVNESETFVAKNTDR-ESPGA-ETVSDLSEKSCVSEKSCVQEDSRAKV------
--LRPTRLTRSRMLRPKPNVVKAAERKEILTSQEKVGAHVEKSE---------DESGVVI
PPQMENESHKNLQCEDT-M----SQPEKKD---PF-EKTQPDQPEVLNECPGIHEGNKE-
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------NKRKQVPVLRTRFQKPKPNTGRRR--RRISSKE-----GLPEEIAISGEISI
---PATWEEI----------PRP-DTSPREEVPSVPLAPLTATASTKDSASD--------
-VKDSGRNDTASNV--EMSEMTDVTMEMETGLETIGR-DTCPGEMG-GEMIDIPMETEAG
L-KTSLNETSP-------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------M---
-ERVPELIDTTGEICTNLGETGRKEVFLQENGPKEVS-PNSELETGLQETGKD-------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------LVMKESTPDM
--TDSTEEREAYSEETE-----------------KQEK--------------------IS
ALIKD--AEEAKARGEMETPLE----EIGGTT--SQRE----EAAGAPVEQSASKEDPRG
SACRE---EVEVGSSTAEGKELNLKETGEGD--ISMVVVSGEKTAIEETNGDSKETERES
SV---SW---KRGSGEIQVGEE---MVADL-GKPEKIDVAP-RER-----EPEE----HS
SGQ-PETDVILSSSD-S-----STGSPQDRK-------------------------NISS
QI-S-VMPTLVEEKETTDKDVSSHLGHVESCSQNSGH--HETDQGIPLPDA----LE-RF
SDT---------------------------------------------------------
-----------------------------------------------------------D
LSKPLP-----------------QEQQPLQVKPAPFLRSRFKKPKPNLSRAALKRATIEA
EHCVPGK---------KS------------------------------------------
---------EACKVEAAMLQQGSDQAASPSP-QHNVPS--------LMTSRENDKSGHEE
EE-AATLPCTQTEKDPSP--PNSSEPKEDSQLTKNQ--ENGLVVPIGTQM-MSTVIQETK
QNVVQTTLPVRGRLQRPRPNVQKARQRQIV---QKGEARD--IAK-N-------------
-----------EGPELQKDETRTC-LTVAN-----SSHIESGVAVDMSSSMSECQVSES-
--------------Q-G-----HADPV--ENLSVNKASVVHEQMR-HENKPYVPSPALLI
RRRFQKAKPNLGGARRKE-EQPGVEKGRTEE--STELTAEDP-LLPKGDWDT--QLSLQA
RE---EADMPLEVSVREEC-VHSEESA----------SDGNDAQVKAGPSEGSRDGTS--
--------EEQ--------------------------------------SLSKQIRSS--
-----CPQLLKESSYPK-----------------TVSHRRTTLSSAS----ECEIEHSW-
KRTHRKM-K---PNVTKGRGSKRIRGKTAKKEPRASK---SMLVTLRASQKEDE--DDAE
DFDSDYEEETYHLAPEELN---KAPVFVPVGLRSPEPVSAQIEETMEE------------
-----------------------LEITMDVADM---TIVEHQLS-HMDTTAQAVQAEKVV
YPPSFEMDVGEQTQEE-SGPSDGSTEAAITLLTMGDIVLQSEIVPGQGD-VGVCVFPDVH
SKDQSHVPFIPDNVNQKIVHDDQGV-CSPV-ISTSHASFEENKIVSK--EQSSRDTAV-V
EEAVEETLPTRNIASTM-S-THLRMESMVVTPELNSEKILEIGELDGHQEVASFCITKGT
EVEIQRE-TEGDDSKA-----------------VELEDKSRAPVTAAETKEEEQP-QCVR
DVEGAGVS-QEAILPARIEDHEENLQEVQVSGAA--VASSEI-------------GQQTL
DSGRSFGESAAEEALKETPTGSGVPVLPVPE----G-APSN-VPEAQREN-PS-P----Q
DVTVNLFANGQQD-GEDEQAFILTLVEIPANATEGFTDAAM--QLMPSSLLPAPILVRSG
NATE-RGDLSGS---LQTSSVVQDASSLSP----------SRSGSSEKPPANLDLTSRKR
FCCSPDESIH--VPPAKKFSL-------APQIDYQECTSEVCSEELNV-FEKTAESCM-G
QG-------IFPTSESTH-ATSKPQKEHNEPT---D---TGSSGSL-DEIKDACVEN-MT
QLPQSEIVSDKE----EKTEPASNSEQRDSVTPSTKPPLTRPGRRPLGFLSLLCPKNS-L
ESDEVTQAHSKKRLKPQIPVSRRNLRKPNLHNTSQKKN--QESSAPLPSPSVTDTLS-DK
TGSSESSATQVS-SDPPLL-KEECKNGPKGASE-EEVTPVSEFVFSDIFI--------EV
DETQ-

MFRRARLSVKPNVRPGVGTR---G------SAAPNPQRGPEAPRPPEP--ATESAPKPAE
PTD--VP--AVDSGGAEPQEQAPGSS---DEKTGDKNN-AAESSTLSSASSQRRKRVSST
SSLVQPSGSAPSQSRPL-------------------------------------------
--------------------------------------------------STVD-HDAPQ
PNPTPAKEKQPCSDRYRIYKARKLREMLKEELRKEK--KQWKNKFSTNESQRPPDRSKMT
MRDFIYY-LPDNNPMTSSVEQEKKPEKSLAPTPTRDRQENQSTQDANDNE----DVEEEV
DDGPLLVPRVKVAEDGSIILDEESLTVEVLRTKGPCVVEENDPIFERGST--TTYSSFRK
NYY-SKPWSNKETDMFFLAISMVGTDFSMIGQLFPHRARIEIKNKFKREEKTNGWRIDKA
FQEKRPFDFDFFAHLLQKVLAEEEKRKQKSTKCQSLKEKAS-KPRKNL-KAKTVTSEEVN
DDPDE----SVNSNISDPERSQNDAETVNEEE--SPSSSGQHLEQAMLEQDQNQEK----
KRRRNQGEANKQEATNLLERVLVHSSPPAAEIHKN-T-------CPSEENESECNKEQIP
SLTQNIDDIAGL------APSEETEMR---------MDPIPSTCNQQD------------
--IMPLARESSESCAVALPVWEPGNTASA-------------DMAHA-ESSCSEGRGADL
KTAAPETEQTENVKPKSRSRLQRPKPNLARAVGKKSAVSQDRQDERNKNS--PSETAAEK
NHMEKETMNESETSVAKNTDG-ESPGA-KTVSDLSEKS------CVQQDSQAKV------
--LRPTRLMRSRMQRPKPNVVKAAERKEILTSQEKFGAHVEKSE---------DESCVVI
PPQTENESHKNLQCEDT-V----SEPGRKD---PF-ENIQPDQPQVLSDCPSIHEGNKE-
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------NKRKQVPVLRTRFQKPKPNTGRRR--RRISSKE-----GIPEETPISGEI--
---PATWEEI----------PSL-DTSLREEVLSVPLAPLTATASTKDSESD--------
-VKDSGRNDTASNA--EMSEMTDVTMEMETGLETIGR-DTCPGEMG-AEMIDIPMETEAG
L-KASLNETSC-------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------M---
-EKVPELIDTTGEICTNLGETGRKEVFLQENGPKEVG-PVSEPETGLQETGKD-------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------LAMKESTPDT
--TDSTEEREAYSEETE-----------------RQEK--------------------IS
ALIKD--AEEAKARGEMETPLE----EIGGGT--SQRG----KAAGAPVEQSASEEEPQG
SACRE---EVAVESSTAEGKELNLRETGEDD-VSSMVVVLGEKTDIEETNGDPKETERES
SV---SW---ERGSGEIQVGEE---MVEDL-GKPEKIDVAP-RER-----EPEE----HS
SGQ-PEADVILSSSD-G-----STGSPQDKV-------------------------NISS
KI-S-VMPTLVEEKETTDKDISSHLGHVESCSQNLGR--HETDQGMPLPDA----LE-RF
SDT---------------------------------------------------------
-----------------------------------------------------------N
LSKPLP-----------------QEQQPLQVKPAPFLRSRFKKPKPNLSRAALKRATIEA
EHCVPGK---------KS------------------------------------------
---------EACKVEAAMLQQDSDQAA-LSP-QHNVPS--------LMASRENDKSGHEE
EEEAAILPCTQTEKDASP--PNSSEPKEGSQLTPNQ--ENGLLVPIGTPM-MNTVTQETR
QNVVQTTLPVRGRLQRPRPNVQKARQRQIV---EKGEARD--IAK-N-------------
-----------EGPELQKDETRTC-LTVAN-----SSHIESGVAVDMSSRVSECQVSES-
--------------Q-G-----HADPV--ENLSVNKASVVHEQMR-HENKPYVPSPALLI
RRRFQKAKPNLGGARRKD-EQPGVEKGRTDE--STALTAEDH-LLQKEDCDT--QLSLQA
RE---KADMPLEVSVRKEC-IHSEESG----------SDRNDAQPNAGPSEGSRDETAKE
QPTS-LGLEEQ--------------------------------------SLSKQIRSS--
-----CPQLWKESSYPK-----------------TVSSRRTPLSSAS----ECEIEHSW-
KRTQRKT-K---PNLTKGRGSKRIRGKTAKKEPRASK---SVLVTLRASQKEDE--DDAE
DFDSDYEEETYHLAPEELS---KAPVFVPVGLRSPEPVSAQIEETMEE------------
-----------------------LEITMDVADM---TVVEHQLS-HMDTTAQAVQAEKAV
YPPSFEMDVGEQTQEE-PGPSDGSTEAAITLLTMGDIVLQSEIIPGQGD-VGVCVFPDVH
SEDKSHAPFSPDNVNQKVVHDYPEV-CSPV-ISTSHASFEENRIVSK--EQSNRDAAV-E
EEAVEETLPTRNTTSTM-S-THLRMESMVVTPELNSEKTLEISESHGHQEVASFCITKET
EVEIQRE-TEGDDSKA-----------------VELEDKSHAPVTAAETKEEEQS-QCVG
DVEGASVS-QEAILPARIEDHEETLQEVQESGTA--VASSEI-------------GQQTL
DSGQSFGESAAKEALKETPKGSDVPVLHGPE----S-VPSH-IPEAQQEN-TG-P----Q
AVTVNPFADGQQD-GEDEQAFILTLVEIPTHATEGFTDAAM--QLMPSSLLPAPILVRSG
NAAE-RGDLSGS---LQTSLVVQDAPSLSP----------SRSGSSEKPPANLDLTSRKR
FCCSPDESIH--VPPAKKSSL-------VPGIDYQECTSEVCSEELNV-FEKTAESCM-G
QG-------IFPTSESTH-ATSKPQKEHSEPT---D---TGSSGSL-DEIKDACVEN-MA
QLPQSEIVSDKE----EKTEPASNSEQRDIVTSSSKPPLTRPGRRPLGFLSLLCPKNS-L
ESDEVTQTHSKKRLKPQIPVSRRNLRKPNLHNTSQKKN--QDSSAPPPSPSVTAPLS-GT
AGSPESSAAQVS-SDQPLL-KEECKNGPKGAPE-EEVTPVSEFVFSDI--------FIEV
DETL-

MFRRARLSVKPNVRPSVGAR------GSTA---PNPQRGQESPRPPEP--ATDSASKPAE
P----TDVPPVDFGGAEPQEKAPRS-S--SEKTGSDND-VEESSRSSPTVSQRRKRISST
SSLVKASVSVPSESHLLS------------------------------------------
---------------------------------------------------PVN-QEAAQ
PTATPTKEKQPCSDRYRIYKAQKLREMLKEELRKEK--KQWKNKYAINESQRPPDRSKMT
MRDFIYY-LPDNNPMTSSLEQEKKTEKPSTPVQTREQ-EGKSTANAEDN-----EMEEET
DDGPLLVPRVKVAEDGSIILDEESLTVEVLRTKGPCVVEENDPIFERGST--TTYSSFRK
NYY-SKPWSNKETDMFFLAISMVGTDFSMIGQLFPHRARIEIKNKFKREEKTNGWRIDKA
FQEKRPFDFDFFAHLLQKVLAEEEKRKQKSVKNHSLKEKKSTKPRKNV-KVKKVACEGVN
DDPDE----SMSSRISDTERSQKDAQTVDEE---SLTLSGKDAEQVALEVDLNQKKRR--
--RKKQDGANELEVNNLLENATVQAGPSKGEK-HKNKCQAIR----PEVKEGECSKEQML
SCTQNIDGIVGF------ASSEKVEK---------RTDPVLSLSNQQDAT----------
--S-VAT-ESSESSTSDLPSLEVGIRALC-------------EVNDA-ESSCTEGRNVDL
KNTSLEIDQTENVKPMLRGRFQRPKPNLSRA-GKKSVLSQGKTEAESKN--SHSKTSVEK
DHLEKDKMNTLDTLRMETTER-EN-PEAETVSM------LGEKNCLQEGSQLKA------
--LTSAKV-RGRLQKPKPNVGKAAGRKEILMSQEEIGASVEKNENESCADRD-------T
PQHMEDQSCKDFEEEDVIL-----QPEKND----SFQNVQPDEPKVLNECLSIQENNKA-
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------NKLNQVPILRTRFQKPKPNIGRGTGRREISSKE-----EVLEKILVSGEM--
---TAALRET----------VRP-DTSPKEMVPAEI-------NTTKEMQSD--------
-LKETGRRAISPRE--KILDVIDVTREMETGLKARGR-EICLRERT-PEVIDATKEIDKD
LGEPGRREIPPHENDPEEVKPVGEMETNLKATGN-ENSPREKTP----------------
----------------------------------------EVIDATQEIDKDLEDTGRRE
ISPQENGPEEVKPVD-----------------------------EMETDLKATGR-ESSP
REKTPEVIDA--------------------------------------------------
-----------------------------------TEEI---------------------
-------ERDLEETEREISPQENGLEEVKPVGEMETDLKAT-GREISPRE--KTPEVIDA
TEKIDKDLEETGRREISPEENGPEEVKPVDEMETDL--------KATGRESFPREKTPEV
--IDAAEEIEIDVEETE-R--------------------------------------EIA
PQENG--PEEVRPVGKMETDLKEIREEI------SQRE----------------------
--------KVLAEISAVREKEIDLKETGKRDI-SMMEKVSGKMAVIEEMETDMKETGRE-
NF---R----ERGSEEICVTEE---KVAEL-KKTGKTDISP-REN-----ELEE---TST
SRQ-TETHLMQSGSNDC-----SAMPSLDIK-------------------------NISS
EVLSMM-HIPVEEKRDSEKEVSSHFSHFRISSQTH-ESDKTEVLGIRSPDV----PE-PF
SDI---------------------------------------------------------
-----------------------------------------------------------N
LSRSLPQEQ-----------------KSLEIKPAPFVRSRFKRPKPNLARAALKRKTTES
EKNIYEK---------KS------------------------------------------
---------ETKKMETIVMQENNEQADTLPSQHD-EAS--------LMISREKDTSG-HR
NEEAVILPCTQTEKNLSS--SNSCEPKEESQSAQAQ--ENDLVVSVGTNN-INTFQQEMK
ESVIQTARPVRGQLQRPRPNVRKTGQRQIV---DKGDAK--GIIK-E-------------
-----------ERTILRKDETEKK-ILTAS-----NPQIETEIE-VPSSTVSEHRMC---
------------ENQ-S-----QVVLV--ENLHINKT---DETIRHE-NKLYVPSSAQMT
RRKFQKAKPNLGRAHSKK-EEPVLEKGTTDQ--SKEGKPEDH-LLQKGASNT--QLLLKE
KA---ELLTSMEVSARKDC-VDSNESALAKIDAELEEAGPSRRVGE----E-----TV-G
DNSLSSVAEEQ--------------------------------------YLDKL---TS-
-----CPQPLKESNYSK-----------------IALDGKTTVSSAS----EYERNRSE-
RRSHR-KIK---PNVTRGRGSKRVRGKTSKKEPRASK---AMLVTLRASQEEE---DDAD
DFESDYEEESCHLAPEEVN---KAPVFVPVGLRSPEPVSAQIEETMEE------------
-----------------------LEITVNVPDVGCIAVVEHELP-NTDVTTEEMKQEENL
NASSFEMTTGEHIQDE-PGTNDGSTEAAITLLTMGDLVLQSEISTEQGD-VGVCILPHVH
SKDKSHIPFSLDNVNHKIVHECQEL-SSPV-ITTSPASFEENKIVSE--EQSSREEISLM
EKVKENAIPTRNTISKV--TSNLRIRSRLAKPKPNLEKTLGTNRFDDYREVSSLCVTKGE
EMETQRE-TEKNASKA-----------------TELEDKNLGPVTTAENKDQ-SKLACVH
GIKGTSIS-PEVNLTERNENQEESSQEVHMLSVAPVASS-ET-------------GPCTL
GLDRGLGENSVEEAQIKDSKGDSVLTLPVPE-----YTPTS-IPEVQQ-ENIINP----Q
DLTVNLVANVPQD-GEDEQAFILTLVEIPTNAVEEFTDATA--QFMPNPLLPAPILVKSV
NTEE-RGDMSIC---LPATSVGQDAVGLSIS---------GRDNS-KKPPDNLDLISRKR
FQCRLDENDH--IPPAKKCLL-------TLRDDCQEYTSEVHSKELTNAFEE-TGVSHKE
Q-------DIFPTSGSTL-TTPEPQRQQVEPA-FQS---RGSR-SP-DA----CIDKNVP
QLPQDEM---IVSDKEERTDAAPKSEQMDSRTSSSKAPLSRPGRRPLGFLSLICSKNS-L
ESDEPMQVHSKKRLKPLIPALRQKLKRSNPFNESQKKN--QDSSDPLPSPSVINTQ----
SKNISSSATQVS--CDQPLLKEGHKSAQKRALQ-GEPTTVSEYFFNDIFIEVDETE----
-----

-----------------GTR------GGHA----CPQRGEAAPEPV------ASAPKPSE
S----AD-HLVDLGGTEPQEKAPRS-S--DEKTDGESQ-VEES----STVSQRRKRVSS-
SALEKPPVSVPSEPHPLT------------------------------------------
---------------------------------------------------AVS-HEAPK
PTSIPAKEKQPCSDKYRIYKAQKLRELLKEELRKEK--KQWKNKYAVAESQRLPDRSKMT
MRDFIYY-LPNNNPMTSSLEQEKKTEKASTPVQTKDQ-ESKSTPDAEESD----DLEEET
DDGPLLVPRVKVAEDGSIILDEESLTVEVLRTKGPCVVEENDPIFERGST--TTYSSFRK
NYY-SKPWSNKETDMFFLAISMVGTDFSMIGQLFPHRARIEIKNKFKREEKTNGWRIDKA
FQEKRPFDFEFFAHLLQKVLAEEEKRKQKSVKNQNSKDKKSSKSQKKV-KVKRAVSEGMN
ESSDE----SLSSKIADTERHEEDVQTIEEQEP-TLTSSEQDPGQAVLESDLHQKQKR--
--RRNRDQADEQEVKSLLGNGTVGSDSSTGEK-HKNECESLM----PEVNEGECSRDQTL
SCLQNADDIVGL------PSSEKDEE---------RTDPIRSSSTQQDDI----------
----------SEPSPSDLPPAEVTATALS-------------EVNSA-ESSSTGERNVDG
KDKSLETNRTENAKPRGRGRFQKPKPSLSRAVVKTPASSHSKAASESKR--PHAETSVEK
IHMEKDKTSTDENLGTENSEK-EN-SEAETISN------SSENICVQEDNQPKT------
--SRAARLTRGRLQKPKPNVGKIAGKKEILISQEKVGSDVEKKEKESCITKG-------X
XXXXXXXXXXXXXXXXXXX-----XXX----XXXXXXXXXXXXXXXXXXXXXLQEANEV-
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------KILKQTPVVRTRFKKPKPNIGRGIGKREIFSKE-----EGSEKIQASGEM--
---ESVLREI----------PRL-ESSPAESVPAEA-------GDSKEIETD--------
-VKDAGRRNGFLSE--KIPETIGHXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXX
XXXXXXXX--X----------XXXXXXXXXXXXX--------XX---XXXXXXXXXXXX-
----------------XXXXX--------XXXXXX---X-XXXXXX--XXXXXXXXXX--
-----XXXXXXXXXXXXXXXXXXXXX--XXXXX------X----------XXXXX-----
-----XXXXXXXXXXXXXXXXXX------------XX-XXXXXXXXXXXXXX--------
-XXXXXXXXXXXX----XXX------------XXX--XX--------------------X
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDEMGKALQKRRKEGISPTE--QVPKTISA
SEERERAWEDLRKRELSPQQKSSEEVKTMGESRGSL--------KETEGDISPTK-MPEL
--GAASEYREAGLEETERE-----------------------------------------
------------------TSPKEIGEEA--------------------------------
-------------------------------------------TTVCEIEGGFQKTEGDV
PS---R----KQIPAMTVASEE---SEPD-WEETGRRDIGE-KEA---------------
--------------------------------------------------------NTSS
NL-----LPVVEEERHSGKEVSSHPRNSQTSLQTP-ELSETEEQPIQSPNF----PE-QF
PDTYLXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--------------------------
---------XXXXXX-----------XX--XXXX----------------X--------X
XXXXXX---------------------XXX-XXXXXXXXXXXXX-XXXXXXXXX------
XXXXXX-----------X------------------------------------------
-------------XXXXXXX-------XXXXXXX------------XXXXX-XXXXX--X
X---XXXX--------------XXXXXXXXXXXXXX--XXXXXXXXXXPYNVNTCGKEMK
ESGIQTTQPLRRRFHRPVPNIRKIEQRQRG---EKGEAK--DIVM-E-------------
-----------ERTMLQKEETKNA---LVA-----DSQIGTDAE-VVPSKVPEYRSH---
------------GDQ-S-----RVVLA--ENLHVNKTSDLDDKTREQ-HKAYPPSPAPLV
RRCFQRPKPNLRSAHCKR-KEPETEKDTANH--KEARKAEDN-VLQQGDSDI--QHLPKK
MA---EPLTSLASSAGKDC-AGPKEAVSAKKDAQFEEFGLSGSVGK----R-----TL-G
GNSPSLVIEEQ--------------------------------------HLSKL---TS-
-----CPQLLKESHYSR-----------------TALDRRSAVPSAS----ECDLDHGE-
KRIQR-KSK---PNVTKGRGSKRNRGKSSKKEPRPSK---AVLVTLRASQEEEE--DDAE
DYASDYEEESYHLAPEELN---KAPVFVPLGLRSPEPVATQIEETMEE------------
-----------------------LEIMVDVPDTTYTAAVEPPLF-TTDGSIQEMKPEENV
NVSLXXXXXXXXXXXXXXXXXXXXX---XXXXXXXXXXXXXXXXXXXXXXXLVPDIPDVH
SKDNSYIHSSPDHVKHNIIHDCPEL-SSPV-ISLSPAPYEEKTIIVE--EQNTSEEVGLL
EKIKENATPTXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXX-TEENGVKG-----------------TDLEDKNLGSIITADNKEQ-NTLACAH
VVEGTSIS-QEANLTEKNDGQXXXXXXXXXXXXXXXXXX-XX-------------XXXXX
XXXXXXX---XXXXXXXXXXXXXXXXXXXXX----XXXYTS-IPEVQQENVLN-A----Q
DLTVNLDANVHQD-AEDEQTFILTLVEIPTDAVEMLTNTEA--QLMPNPLLPAPIWVKSV
NTGK-RSDLXXX---XXXXXXXXXXXXXXXX----------XXXXXXXXXXXXXXXXXXX
XHFGLEENDY--IPPTKKSSF-------TSIDGCQEYTLEVCSKELINVFEE-TGESSKG
Q-------NVFPTSGSTY-ATPEPQKEQFKST-LQS---VETG-SP-DEIVDPHRERTTP
QLPPDGM---VVSDKEQRTATACKSEPVDSRTPSSKTPLTRPGRRPMGFLSLICSKNN-L
E-SEPTQVHTKKRLKPLIPVSRKSLKRSNPPNKSRQKP--QGSSDVAPSSDAVHNQ----
SENIDTSAAQVP--CDQPLLQQGS-TGKNQIP--EEPNTISEYV----------------
-----

MFRRARLSVKPNVRPSVGAR------GSTA---PNPQRGQESPRPPEP--ATDSASKPAE
P----TDVPAVDFGGAEPQEKAPRS-S--SEKTGSDND-VEESSRSSPTVSQRRKRISST
SSLVKASVSVPSESHPLS------------------------------------------
---------------------------------------------------TVN-QEAAQ
PTTTPTKEKQPCSDRYRIYKAQKLREMLKEELRKEK--KQWKNKYAVNESQRPPDRSKMT
MRDFIYY-LPDNNPMTSSLEQEKKTEKPSTPVQTREQ-EGKSTANAEDN-----EMEEET
DDGPLLVPRVKVAEDGSIILDEESLTVEVLRTKGPCVVEENDPIFERGST--TTYSSFRK
NYY-SKPWSNKETDMFFLAISMVGTDFSMIGQLFPHRARIEIKNKFKREEKTNGWRIDKA
FQEKRPFDFDFFAHLLQKVLAEEEKRKQKSVKNHSLKEKKSTKPRKNV-KVKKVACEGVN
DDPDE----SMSSRISDTERSQKDAQTVDEE---SLTLSGKDAEQVALEVDLNQKKRR--
--RKKQDGANELEVNNLLENATVQAGPSKGEK-HKNKCQAIR----PEVKEGECSKEQML
SCTQNVDGIVGF------ASSEKVEK---------RTDPILSLSNQQDAT----------
--S-VAT-ESSESSTSDLPSLEVGIRALC-------------EVNDA-ESSCTEERNVDL
KNNS-EIDQTENVKPMLRGRFQRPKPNLSRA-GKKSVLSQGKTEAESKN--SHSKTSVEK
DHLEKDKMNTLDTLRMETRER-EN-PEAETVSM------LGEKNCLQEGSQLKA------
--LTSAKV-RGRFQKPKPNVGKAAGRKEILMSQEEIGANVEKNENESCADRD-------T
PQHMEDQSCKDFEEEDVIL-----QPEKND----SFQNVQPDEPKVLNECLSIQENNKA-
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------NKLNQVPILRTRFQKPKPNIGRGTGRREISSKE-----EVLEKILVSGEM--
---TAALRET----------VRP-DTSPKEMVPAEI-------STTKEMQSD--------
-LKETGRRAISPRE--KILDVIDVTREMETGLKARRR-EICLRERT-PEVIDATKEIDKD
LGETGRREIPPHENDPEEVKPVGEMETNLKATGN-ESSPREKTP----------------
----------------------------------------EVIDATQEIDKDLEDAGRRK
ISPKENGPEEVKPVD-----------------------------EMETDLKATGR-ESSP
REKTPEVIDTTEEIEIDLEETER-EISPQENGPEEVK-PLGEMETDLKAAGR--------
---------------------ESSPREKTPEVIDATEEI---------------------
-------EIDLKETEREISPQENGLEEVKPVGEMETDLKAT-GREISPRE--KTPEMIDA
TEKIDKDLEETGRREISPEENGPEEVKPVDEMETDL--------KATERESFPREKTPEV
--IDAAEKIEIDVEETK-R--------------------------------------EIA
PQENG--PEEVRPVGKMETDLKEIREEI------SQRE----------------------
--------KVLAEISAIREKEIDLKETGKRDI-SMMEKVSGKMAVIEEMETDMKETGRE-
NF---R----ERGSEEICVTEE---KVAEL-KKTGKTDISP-REN-----ELEE---TST
SRQ-TETHLMQSGSNDC-----SAMPSLDIK-------------------------NISS
EVLSMM-HTPVEEKRDSEKEVSSHFSRFRISSQTH-ESGKTEVLGIRSPDV----PE-PF
SDI---------------------------------------------------------
-----------------------------------------------------------N
LSRSLPQEQ-----------------KSLEIKPAPFVRSRFKRPKPNLARAALKRETTES
EKNIYEK---------KS------------------------------------------
---------ETKKMETIVMQENNEQADTLPSQHD-EAS--------LMITREKDTSG-HR
NEEAVILPCTQTEKNLSS--SNSCEPKEESQSAQSQ--ENDLVVSMGTNN-INTFQQEVK
ESVIQTARPVRGRLQRPRPNVRKTGQRQIV---DKDDAK--GIIK-E-------------
-----------ERTVLRKDETEKK-ILTAS-----NPQIETEIE-VPSSIVSEHRMC---
------------ENQ-S-----QVVLV--ENLHINKT---DETIRHE-NKLYVPSSAQMT
RRKFQKAKPNLRRAPSKK-EEPILEKGTTDQ--SKEGKPEDH-LLQKGASNT--QLLLKE
KA---ELLTSMEVSARKDC-VGSNESALAKIDAELEEAGPSRRVGE----E-----TV-G
DNSLSSVVEEQ--------------------------------------YLNKL---TS-
-----CPQPLKESNYSK-----------------IALDGKTTISSAS----EYERNRSE-
RRSHR-KIK---PNVTRGRGSKRVRGKTSKKEPRASK---AMLVTLRASQEEE---DDAD
DFESDYEEESCHLAPEEVN---KAPVFVPVGLRSPEPVSAQIEETMEE------------
-----------------------LEITVNVPDVGCIAVVEHELP-NTDVTIEEMKQEENL
NASSFEMTTGEHIQDE-PGTNDGSTEAAITLLTMGDLVLQSEISTEQGD-VGVCILPHVH
SKDKSHIPFSLDNVNHKIVHECQEL-SSPV-IPTSPASFEENKIVLE--EQSSREEISLM
EKVKENATPTRNTISKV--TSNLRIRSRLAKPKPNLEKTLGTNRFDDYREVSSLCVTKGE
EMETQRE-TEKNASKA-----------------TELEDKNLGPVTTAENKDQ-SKLACVH
GIKGTSIS-PEVNLSERNENQEESSQEVHMLSVAPVASS-ET-------------GPCTL
GLDRGLGENSVEEAQIKDSKGDSVFTLPVPE-----YTPTS-IPEVQQ-ENIINP----Q
DLTVNLVANVPQD-GEDEQAFILTLVEIPTNAVEEFTDATA--QFMPNPLLPAPILVKSV
NTEE-RGDMSIC---LPATSVGQDAVGLSIS---------GRDNS-KKPPDNLDLISRKR
FQCRLDENDH--ILPAKKCLL-------TLRDDCQEYTSEVHSKELTNAFEE-TGESHKG
Q-------NVFPTSGSTL-TSPEPQRQQVEPA-FQS---RGSR-SP-DA----CIDKNVP
QLPQDEM---IVSDKEERTDAAPKSEQMDSRTSSSKAPLSRPGRRPLGFLSLICSKNS-L
ESDEPMQVHSKKRLKPLIPALRQKLKRSNPFNESQKKN--QDSSDPLPSPSVINTQ----
SKNISSSATQVS--CDQPLLKEGHKSAQKRALQ-GEPTTVSEYFFNDIFIEVDETE----
-----

MFRRARLSVKPNVRPGVGAR------GSTT---PNPQRGQEAPRPQDP--AAASSPKPAE
S----TDVPPVDCGGSEPQEKASRS-S--DEKTDSENY-VEEASKSSSTVSQRRKKVSST
PTLVKPGVSVPSESHPLS------------------------------------------
---------------------------------------------------TVN-QEVPQ
PNPLPTKEKQPCSDRYRLYKAQKLREMLKEELKKEK--KQWKNKYAINESQKPPDRSKMT
MRDFIYY-LPDNNPMTSSLEQEKKTEKSLTPVQTREQ-EGKSTPDTADNE----ELEEEV
DDGPLLVPRVKVAEDGSIILDEESLTVEVLRTKGPCVVEENDPIFERGST--TTYSSFRK
NYY-SKPWSNKETDMFFLAISMVGTDFSMIGQLFPHRARIEIKNKFKREEKTNGWRIDKA
FQEKRPFDFDFFAHLLQKVLAEEEKRKQKSVKSQSLKEKKSSKPRKNV-KVKKVASEGGN
DDPDV----SPSTKISDTEPSQKDAQIVEEEQQ-SQTLTGQDSEQIALEPELNQKKKR--
--RKNQDEVGKQEIENLSGNGTVQLGHSKGEE-YKNGGQSLR----PEI-NEDEVNKEQL
SCIQNMDDLVDL------SSSEKAEK---------RTDPILLLSGQQDAT----------
--S-LAT-EASESSPSDLPLSEAGISALC-------------EGNNV-ESSCTEESSVDL
KNKSLETDQSGNVKLIGRRQLHRPKPNLSRAVGKKSVLSQGKTDAESKSL-HAETSVEKN
HMMEKDKVNTLDVSGMENTER-EN-PEAETVSN------LSQKIGLQEDDQTKA------
--LGPARLRRGRLQRPKPNVGKAAERKEILASQEKIEANVKKNESESCIARD-------S
PEQVEDQSCKNAGFEDITL-----QSE-KEDNSFQMN---------VNECVSIQEDNKV-
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------PVLKTRFQKPKPNIGRGARRREIFSKE-----EVSQEIVASGQF--
---IAPLREI----------TRVEETLPSKRISMEA-------NTSKEMESY--------
-LKETEG-DNPPRE--KIPEMMDNTVEMETDLKETGR-EVSPGDTV-SEVSDITEETVI-
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------NLEDT-GREVSPRD--TVSEVSDV
TEERVTDWEETGRREISLQENALE-LSTIDEIETGL--------EETGSKVSVRENVPEM
--VDTTEEKETHLEETERK--------------------------------------EID
TDGKA--PQVKTQN-EMGTDWKEIEKGT------SLRE----------------------
--------KVLVGISAIGEREIDSKQTGERDL-SLIEKVSGKTTAIEETEVESKEDGGDI
SL---K----KCISEEMSAPEE---MAADL-EKTGKIDIPL-RKN-----GAEE---TRT
SRQ-TDTDFMQSSTSCS-----STVPSLNIK-------------------------NVSS
EVPSMV-HRPEEEKRNSEKELSDHLNCLKTSLQTS-EPDKREDQGMLSPDV----PE-QF
SDT---------------------------------------------------------
-----------------------------------------------------------N
LSKSLPQEQ-----------------KPLEVKPAPFVRSRFKRPKPNLARATLKRETTEA
EKYVSGK---------KL------------------------------------------
---------ETGKTEAVVVQHSSEQMNTLPSQHD-MAS--------VMTSREKDKSG-QR
EEETVILPCIQTEKDLSP--LSSCDPEEKSQPTQAQ--EKELIVSTGAHN-TNTFQQEVK
ESVIPTARTVRSRFQRPRPNIRKTGQRQIE----KGEAE--SVIK-E-------------
-----------ERTIVQ-KDETKK-FLTAP-----NSPVGTEIE-VVSSEVSEGRMN---
------------ENQ-S-----HVVLV--EPLHLNRINVLDEKMRHE-PKRSIPSPAHLV
RRQFQKAKPNLRRVHGKK-EEPGTEKDRADQ--SEARKPEDN-LLQPGDSNT--NLLQKE
KA---EFLTSLEVSARKDC-VDSTESSLGKNGARS-EAGPSGSVEE----K-----TV-G
DNSVSSVAEEQ--------------------------------------CLSKL---SS-
-----SPQLLKESNHSK-----------------IGLDRKAMASPAS----EREVDHIG-
RRTHR-KMK---PSVTRGRGSKRVRSKTSKKEPRASK---ATLVTLRASQEEDE--DDDE
DFEPDYEDESYHLAPEEVN---KAPVFVPIGLRSPEPVSAQIEETMEE------------
-----------------------LEITVNVPDIG-IAVVEHPLS-NTDVTAQATKQEENL
KALPVEMNTGEHTQDE-TGTNDGSTEAAITLLTMGDLVLQSEIGAEQSDVIGVCVLLDVH
SKDKSCVPFSPDNINHKIVGECQEL-SSPV-NSTSPSSLEENKIVLE--EQSAKEEIGLV
EKVKENALSTRNTTSEV--TSNLRMRSRFAKPKPNLKT-SGTNRFGVHQEVPNLFVNKGE
VVENQRE-TEKNASEV-----------------TELQDENLGSLTTAENKEQ-SKLACEH
GTEETAVS-QEANPTERNDDQEGESQKVQILSVAPVVSF-ET-------------RPHTL
GSDTVLTESSIKEPQTEDSNGDGVLTLHVSE----GI-PTS-MPEVQQENVGPVN----Q
DLTVNLVANEHQD-GEDEQAFILTLVEIPTDAVEEFGDATA--QLMPNPLLPAPILIKSV
NTAE-RSDMSMS---FPVTSVGQDTMCLSDS---------GKGDSEKPPPANLDLTSRKR
IYCTLDESDH--VPPAKKSLL-------TSRDDCQNYMSEVCSKEMINVSEE-TGDSYKE
Q-------DTFPTSGSTH-TTPEPQKEQLEPT-SES---IGSG-SL-DKITDTHVEKSTS
QLPQDEK---IVSDKEERTCAASKSERMDSIASSSKTPLSRPGRRPLGFLSLICSKSS-L
ESDEPTQVYNKKRLKPLIPIPRRNLKRSNALNESQKKI--QESSDQLPSPSVVDTQ----
SESIGSSATQVS--CDRPLPKEECKSGQNRVPE-EEPTTVSEYFFSDIFIEVDETE----
-----

MFRRARLSVKPNVRSGTGAR------GSTA---PSLQRGQESPRLPEP--AADSASKLAE
P----TDVPVVDFGRAEPQEKAPRS-S--DAKTGDEKD-VEESSKSSFPVSQRRKRLSST
SSLVKPSVSVPAESHPSS------------------------------------------
---------------------------------------------------TVN-QETPQ
PNPIPAKEKQPCSDRYRIYKAQKLREMLREELRKEK--KQWKNKYAINESQGPPDRSKMT
MRDFIYY-LPDNNPMSSSLEQEKKTEKLLTAVQTREQ-EGKSTPDAVDNE----ALEEET
DDGPLLVPRVKVAEDGSIILDEESLTVEVLRTKGPCVVEENDPIFERGST--TTYSSFRK
NYY-SKPWSNKETDMFFLAISMVGTDFSMIGQLFPHRARIEIKNKFKREEKTNGWRIDKA
FQEKRPFDFDFFAHLLQKVLAEEEKRKQKSVKNHSLKEKKSSKSRKNV-KVKKVACEEVN
NDPDA----SVSTNISDTERSPKDVQTVE-E-D-SLTLSRQDSEQVALEQDLNQKERK--
--RKNQEAANESEVNSLVGNDTVRSSPSKGEK-HKNKCQSLR----PEVNEDEYN-KEQL
PCLQNIDDIVDL------ATSEKVEK---------ITDPILSSSNQQDAM----------
--L-VAT-ESSELGTSDLPSLAVGIRTLC-------------EENNA-DSSCTQERNVDV
KNKSLETDQMENVKPVLRGRLQRPKPNLSRAVGKKSVLSQGKTDAESKN--SHSETSVDK
NPMEKDKMNILDISGMENAER-EN-PEAKTVFN------LSEKKCLQEDDQAKA------
--LRSARVTRGRLQRPKPNVGKAAERKEIFASLERNGTNVEKNKNESWIDRD-------T
PQQMEDDSCKNFECEDITT-----QAAKKD----SFQDIQPDEPKVLNECLSIQEDKKA-
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--------PILKQAPILRPRFQKPKPNIGRGTKRREISSKE-----EIPEEILVSG----
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Query Results

"ENSGT00390000012762_0"

ENSGT00390000012762_0