Query Results 

----------------------------MKNVEFS--------LERGQMLKMPARKLREI
VSPNQGNKLAVVEDEL------PR-VPPALA-ANKRLAVETRTS-SNGTLCGSLDLTSAR
LYHQPLS-E----SPPASKK--SDFSKDAVVRR--LPLNKTEENNAPKA

PF15324 // ENSGT00390000012397_0_Domain_2 (170, 1644)

NDI--FISQYT
MGQKDALRTVLKQKA---------------------------------------------
-----QS------MPVFKAVKVHLFEDTSTEKNTV-AQETETLPNRIDSATTVAAATAAA
IATAAPLIKVQSDLEAKVNCVGELLTKLQETDKQLQRVTEHQASVQSK-QEKVHCH----
-DHEKQMNVFMEQHIRHLEKLQQQQIDIQTHFIDAALKASSL---Q-LGMSTSRAVEKYS
GKL-GSPSVGS-SVFSHNTFVSKRV---------------------PLS--EDTDFDGQK
SPLETPAPRRFAPVPVSRDGKIT----KRESPTEEKENMEMNSP------KGNVRLLEQV
LNSNECLTRKTES-SDITSLTQPKMGWNLEKRDSTETLHSQ-IFPSSE----ERGTAQVP
VPKYNDVVHDLGQKK-QASDMPQIKQSPVTL-----------------------------
----------------------RLS---DHPHNPA-LLQTT-NTRSVLKDAAKILRGVQN
NKKVLEENLEAIVRAKDGAAMYSFINALATNREMSEKIRIRKQVDEWIKIISAEIQDELM
RKDYEQKR---FDPKNQ--RNKKAL-T----MSRDIKANNQEKT----VNRSVIPRSHYQ
KQTQEQFTSLPVR--NLPASGPQK-ER-SGLLKSTTTLQDEDYM-LQIYGKPVYQGHRST
LKKGPYLRFSSPSPKA-KPQRPRVIELVKGTKVKSAKTQTDFHAASRMKMDSKIQHPITA
-LPHAD-QQYMFSPSREMPTVSGTLEGHLIPMAILLGQTQSNSDSMPPAGVTVNKPRPVT
VTTSIPP---ASRKGNAGVKKPNVAIVEMKSEKKGPPQLSVQILPSVDIDSVSYSSTDGA
SSP-PSP---KEAS-LPPLHTWIQTPDFMKVDEEEVPLPGTNFDEVIDVIQEE-EKRDEI
PECSAPMLEFNRSVKVVPSKYNGPSFPPVVSAYHP--TTDILDKVIERKETLE--NSLIQ
WVEQEIMSRIISGLFPLQQ-QARLDASVS-VSEASEPSASDIVAGTSSGALQRMVDARVP
VNSDMVSHFVNEALAETIAVMLADREAERQRAAATSVPGDLLGTETNL-LARVCAPVATP
QPTPPCSPS-----PVREHVRVKTPDSSPCESDPDAASSIKEIRVEK----GSDMPAVML
VSTPTRTPVATPPPAA--ALTP-TLSETSIDKLKLSSPELPKPWDSGDLPLDEENPNS-L
QE----L-PHPRAVV-M-SVANEEPES-VDFSAQPAPPE-PAPSAPLPEGTKAPSLQRVP
SSGSSTLENTLS--TVTETETLDRHISEGEILFSCGQNLATK----RPG--DLFLMNIND
SLSSTLQDALEMEDDPPSEGQVI-RRPHKKRHEDAIVALLTKQQRELLVSQQE------E
DLENSVGELSEGQRLVLKA-A-EDISAGPA-GRMLPP-TSLAEPSYQHADPRLVLQQSDM
A-SGNICEDLCASHGPMSLRELELQPDSNLILPITHTT-TAVSDGNLPEAAE--------
--------------------DFSQYQQK--QDSDIKQLEHK---PIQRHLTSVRNKPDSS
LSQH--------------------------QGGPADLLLIAHVSP--------ARMSVTL
PSANLEDCSQSLST--------------------------SSTHGGAESSGTDTF-----
---------------

----------------------------MKNLEFS--------LERGRRVKMPARRLREV
LSPNQRDNSAVVEDEL------PR-VPPALS-ANKRLAVGVRTG-PNGTSYGSLDLTSAR
KHHQLLS-E----NPPVADK--SDFSKDAVVPR--LPLNKTEENSTHKA

PF15324 // ENSGT00390000012397_0_Domain_2 (170, 1648)

NDI--FISQYT
MGQKDALRTVLKQKA---------------------------------------------
-----QS------MPVFKEVKVHLLEDTSVEKNAV-APETASSPNRIDSATTVAAATAAA
IATAAPLIKVQSDLEAKVNSVAELLSKLQETDKQLQRVAEHQTSIQSK-QEKSQCH----
-DHEKQMNVFMEQHIRHLEKLQQQQMDIQTHFIGAALKANSL---QLVGTSPSRAVEKHS
GKP-GHPNLGS-SVSSHNTFVSKQV---------------------PLRGVEDTDSDGQK
SPLETPAPRRFAPVPVSRDGRIS----KRENPTEEKENMEMSSP------KGNVRLLEQI
LSSNDSLTRRCES-SNITSLARSKPGWNSEKRDSIETLRSQRTFPSSE----ELGTAEVA
MQKYNDDVHDLGQKKKQTNDLLQVKQSPVIL-----------------------------
----------------------KFS---DLPQNPV-KLQTT-NTRSVLKDAEKILRGVQN
NKKVLEENLEAIIRAKDGAAVYSFINALSTNREMSEKIRIRKKVDDWIKIISAEIQDEFS
RKDYEQKR---FDPKNQ--WNKQAL-T----MSRDIKVNTQDRA----ANRSVIPRRHGQ
KPVQEQSRGVPVK--SFPTSGSQK-ERKEGLLKSTTVLQDEDYM-LQIYGKPVYQGHRST
LKKGPYLRFSSPSPKA-RPQRPKVIERVKGTKVKSARTQTDFYTAKPVKVDSKVHQPITT
-LPHGD-QQYLFSPSREMPTVSGTLEGHLIPMAILLGQTQSNSDSIPPAGVMVNKPHPVT
VTTSIPP---SSRKVEAGVKKPNVAVVAMKSEKKDPPQLSVQMLPSVDIDSISYSSVDGV
SSP-PSP---KEAS-LPPLNTWIQTPKFLKVDEEEVNLPGTNFDEVIDVVQEQ-EQRDEI
PECSAPVLEFNRSVKVIPTEYNGPSFPPVVPTFHP--TTDILDKVIERKETLE--NSLIQ
WVEQEIMSRIISGLLPLQQ-QARLDDSVS-VSEASEPSASDIVPGTSNGALQLFVDAGVP
VNSDVISRFVNEALAETIAVMLGDREAKKPGPVATSVSGDLSTNETNL-PERVCAPVPTP
QPTPPCSPSPPP--PPEEYVLAKTPDSSWDSEQEDVASPSKEI--------RGAIPAVTP
VGTPTVTPVTTPPPAA--ALTP-TLSDISIDRLKVSSPELPKPWGSGDLPLDEENPNS-V
QE----Q-LHPRAVV-MSVAKDEEPGS-VDFPAHPVPLE-PAPSAPLPEGTKA-APQQTP
SSGSSTLENTLS-VTVTESETLDRHISEGEVLLSCGQNLAPK----RNG--DLY-LNIND
SLSSTLQDALEMEDDPPSEGEVI-RRPHKKLHANSILSLFTKQEQELLVSQQE------E
DVDNSVGELSEGQRLVPAA-A-EDILAGLSVVCLPQP-TTAAEPCSERAAPGTFLQPSDV
T-SGNICEGSCASHGPMSLRELELQPCSGLILPMTHKT-TKGNDAELPGAAE--------
--------------------DSSQYQQQ--QDADNKQVEQK---PVHRQLTSVRNKSDSS
LSQQ--------------------------KG--PFPLFTAHMSP--------TKMSVTL
PSANLEDGSQSLST--------------------------S-MQADGESSGTDTF-----
---------------

------------------------------------------------------------
------------------------------------------------------------
---------------FHIP---KDFPKDVAVQG--LPVDKLEESNRQKA

PF15324 // ENSGT00390000012397_0_Domain_2 (170, 1649)

NDI--FISRYT
MGQKDALRAVLKQ-----------------------------------------------
---KTQN------MPVFKEVKVQLLEDAGTEKDAV-TQETRTSPSGIDSATTVAAATAAA
IATAAPLIKVQSDLEAKVNSVTELLNKLQETDKQLQRVTEQQTSIQNK-HEKLHCH----
-DHEKQMNVFMEQHIRHLEKLQQQQIDIQTHFISAALKTGSF---QPVSMPPSRVMEKYS
VQP-DYSDLGSSNLSSHNTFASRQA---------------------PSREAEDTGFNKQK
SPLETPAPRRFAPIPVSKDDKIS----KRGNPMEEKENMETVGH------SGNVRLLEQI
LNNHDSSTRKSES-SDKTLLNRSKTEWNPESRD---------RFPSCE----ELGAAKLT
VQRSDDFLHDPGQKRKETNGIVQPKESLIMS-----------------------------
----------------------RLA---DLPQNSI-KLQTT-NNRSVLKDAEKILRGVQN
NKKVLEENLEAIIRAKDGAAMYSFINALSTNREMLEKIRIRKTVDEWIKTISAEIQDELS
RKDYEQKR---FDQKNQ--RTKKVQ-N----MSKDVKTNIQDKT----ANNSIIQRKHSQ
KQKEEHFRNPLMR--NIPASNLQK-ERKEGFLKATTVIQDEDYM-LQIYGKPIYQGHRST
LKKGPYLRFNSPSPKS-KPQRPKVIEQVKGTKVKSIRTQTDFYAMKPVKMDSKSQHSIPM
MLPPGD-QHYLFSPSREMPALSGTLEGHLIPMAILLGQTQSNSDSMPPPGVIVNKPHPVT
VTTSIPP---SSRKTETGVKKPNIAVIEMKSEKKDPPQLTVQVCQGAQIDNFKGRKFK--
----PAS---DPLS--PSLSLPLPNSEFMKVDEEEVKFPGTNFDEVIDIIQEE-EKPDEI
PEYSEPILEFNRSVKVVSTKYNGPPFPPVVSTVQP--TTDILDKVIQRKETLE--NSLIQ
WVEQEIMSRIISGLFPIQQ-QSIANVSAS-VSEASEPLTSDIVEGTSNGVLQLFVDAGVP
VNSDMISHFVNEALAETIAVMLGDREAKKQGPAAPSVSGDVSTSNTYL-PARVCTPVPTP
QPTPPRSPSS----PPKESVLVKTPDSSPYDSDHDLAIPVKEIFAEK----GNVMSAITL
VNTPTVTPATTPPPAA--ALTP-TLSEISIEKLKISGPGRPKPWSDGDLPLEEENPNS-L
QE----E-LHPRAIV-MSVAKDEEPES-VDFPAQPAPPEPPVPFMPLSAATNVPSLIQMP
ASDSSTTESSLS-ITVTETETLDRPLSEGEILLNCGQKMAPK--ILGDG--RLCLTNLND
SLSSTLHDALEMEDDPPSEGQVI-RMPHKKTPTDGILSLLAKMTQESLVSQQAVYPS--E
DLEYSAGELSEGQRPRLTA-AAENILLGHS-VPVQPP-ATNAESLDQKCAPNPLSQQFDT
V-TGGVYEDSCASHGPMSLGELELQPNSNLALPTTLLT-VQENDVQLSGAVE--------
--------------------DNHQYQQK--HDQDAKQVEHK---PAQSRLIRVRSKSDIS
LSQ-QQASS--GDTDQTQIEPN-LYLTSVFTGGKTVPLFTSQTSP--------AKMSVTL
PAVKPEDCSQSLSV--------------------------SNVQGDTESSGADTF-----
---------------

------M--------FWVMGTCFVT-NNMKASEVS--------LEKKKRIKMPAKRLREV
VSQNRGDHLVLLKDDL------PC-VPPALS-ANKRLPVGAGTS-LNGTSRGSSDLTSAR
NCHQPLK-E----NPMASE---SDFSKDDAVQV--LPLDKIEENNKQKANDI--FISQYT
MGQKDAVRTVLKQKQCLTLSHMLECSGVITTHCTLYL---------LRLMRSFHLSLLSN
WDY

PF15324 // ENSGT00390000012397_0_Domain_2 (244, 1649)

RSQSM------PVVKEVKVHLLEDAGIEKDAV-TQETRISPSGIDSATTVAAATAAA
IATAAPLIKVQSDLEAKVNSVTELLSKLQETDKHLQRVTEQQTSIQRK-QEKLHCH----
-DHEKQMNVFMEQHIRHLEKLQQQQIDIQTHFISAALKTSSF---QPVSMPSSRAVEKYS
VKP-EHPNLGSCNASLYNTFASKQA---------------------SLKEVEDMSFDKQK
SPLETPAPRRFAPVPVSRDDELS----KRENLLEEKENMEVSCH------RGNVRLLEQI
LNNNDSLTRKSES-SNTTSLTRSKIGWTPEKTN---------RFPSCE----ELGTTKVT
LQKSDDVLHDPGQKEKETNSMVQPKESLSML-----------------------------
----------------------KLP---DLPQNSV-KLHTTNTTQSVLKDAKKILRGVQN
NKKVLEENLEAIIRAKDGAAMYSLINALSSNREMSEKIRIRKTVDEWIKTISAEIQDELS
RTDYEQKR---FDQKNQ--RTKKGQ-N----MAKDIRTNTQDKT----VNKSVIPRKHSQ
KQIEEHFRNLPMR--GMPASSLQK-ERKEGLLKATTVIQDEDYM-LQVYGKPVYQGHRST
LKKGPYLRFNSPSPKS-KPQRPKVIERVKGTKVKSIRTQTDSYATKPMKIDSKMKHSIPM
-LPHGD-QQYLFSPSREMPTFSGTLEGHLIPMAILLGQTQSNSDTMPPAGVIVSKPHPVT
VTTSIPP---SSRKVETGVKKPNIAVVEMKSEKKDPPQLTVQVLPSVDIDSISNGSTDVG
SPL-SSP---KEAS-LPPVQAWIRTPEIMKVEEEEVKFPGTNFDEIIDVIQEE-EKCDEI
PD-SEPILEFNRSVKADSTKYNGPPFPPVASTFQP--TANILDKVIERKETLE--NSLIQ
WVEQEIMSRIISGLFPIQQ-QIAPNISVS-VSETSEPLTSDIVEGTSSGALQLFVDAGVP
VNSDVINHFVNEALAETIEVMLGDREAKKQCPVATGVSGNASANETYL-PARVCTPLATP
QPTPPCSPSS----PTKECVLVKTPDSSPCDSDHDMAFPVKEICAEK----GDDIPAIML
VKTPTVTPTTTPPPAV-AVFTP-TLSDISIDKLKVSSPELPKPWGDGDLPLEEENPNS-P
Q-----EELHPRAIV-MSVAKDEEPES-MDFPAQPPPPE-PVPFMPFPAGTKAPSPSQMP
GSDSSTPESTLS-VTVTETETLDKPVSEGEILFSCGQKLAPK--ILEDV--GLYLTNFND
SLSSTLHDAVEMEDDPPSEGQVI-RMPHKKFHADAILSVLAKQNQESAVSQQAVCHS--E
DLENSVGELSEGQRPQLIA-AAENILMGHS-LYMQPP-VTNAQSLDQQCDPKPLSRQFDA
V-SGSIYEDSCASHGPMNLGEMELEPNSNLVLPTTLLT-LQENDVNLPVAAE--------
--------------------DFSQYRQK--RNQDVKQVEHK---PSQS-YLHVTNKSDIA
PSQ-QQ-----GDMDQTQNELN-PYLTCVFTGKSFTLKKV----SCIGKLGPWGFVIQII
PS-----PRWESNATLRFTDAPCQDVHDAALSEPRGLLSVSEH--QHNAGGRGVFRGRYL
LNGKRQPAQCLCH--

------------------CGTSFVT-DNMKGSEVS--------LQKKKSVKMPAKRLREV
VSQNHEDHLVLLKDKL------PC-VPPALS-ENKRLPVGTGTR-VNGTSRGSSDLTSAG
NCYQSLL-E----NPMVSE---SNFSKDVAVQV--LPLDKIEENNKQKE

PF15324 // ENSGT00390000012397_0_Domain_2 (170, 1649)

NDL--FICQYT
TGQKDALRTVLKDGVSLCWSG-----------CLL-------------------NTFLLL
FTYRAQSM------PVFKEVKVHLLEDADIEKDAV-TQETRISPSGIDSATTVAAATAAA
IATAAPLIKVQSDLEAKVNSVTELLSKLQETDKHLQRVTEQQTSIQSK-QEKLHCH----
-DHEKQMNVFMEQHIRNLEKLQQQHIDIQTHFISAALKTSSF---QPVSVPSSRAVEKYF
VKP-EHPNLGSCNPSSYNTFASRQA---------------------PLKETEDMSFDKQK
SPLETPAPRRFAPIPVSRNDELS----KRENLLEEKENMEVSCH------RGNVGLLEQI
LNNNDSLSRKSES-SNTTSLTRSKIGWNLEKTD---------RFPSYE----ELGTAKVT
VQKSDDVLHDLGQKKKETDGMVQPKESLSML-----------------------------
----------------------KLA---DLPQNSV-KPQTSNTTKSVLKDAEKILRGVQN
NKKVLEENLEAIIRAKDGAAMYSLINALSTNREMSEKIRIRRTVDEWIKTISAEIQDELS
RTDYEQKR---FDQKYQ--RTKKAH-N----MTKDIRTNTQDKT----VNKSVIPRKHSQ
KQVEEHFRNLPIR--GMPPASIQK-ERKEGLLKASTVIQDEDYM-LQVYGKPVYQGHRST
LKKGPYLRFNSPSPKS-KPQRPKVIERVKGTKVKSIRTQTDFYATKPIKMDSKMKHSIPM
-LPHGD-QQYLFSPSREMPTFSGTLEGHLIPIAILLGQTQSNSDSVPPAGVIVSKPHPVT
VTTSIPP---SSQRVETGVKKPNIAVVEIKSEKKDPPRLTVQVLPSVDIDSISNGSADAS
SPL-PSP---KEAS-LPPVQTWIKTPEIVKIDEEEVKFPGNNFDEIIDVIQEE-EKCDEI
PD-SEPILEFNRSIKPDSTKYNGPPFPPVASTFQP--TADILDKVIERKETLE--NSLIQ
WVEQEIMSRIISGLFPVQQ-QIAPNISVS-VSETSEPLTSDIVEGTSSGALQLFVDAGVP
VNSDMINHFVNEALAETIAVMLGDREPKKQGPVAASVSGGASTNETYL-PARMRTPLATP
QPTPPPSPSS----SPKECVLVKTPDSSPCDSDHDMAFPVKKVLAEK----GDDMPAIML
VNTPVVTPTTTPPPA--AVFTP-TWSEISIDKLKVSSPELPKPWGDGDLPLEEENPNS-P
Q-----EELHPRAIV-MSVAKDEEPES-MDFPAQPLPPE-PVPFMPFPAATKAPSPSQMP
GSDSSTLESILS-VTVTETETLDKPISEGEILFSCGQKLAPK--ILEDV--GLYLTNLND
SLSSTLHDAAEMEDDPPSEGQVI-RMPHKKFHADAILSLLAKQNQESAVLQQAVYHS--E
DLEKSVGELSEGQRPQLTA-AAENILMGHS-LCMKPP-VTNAESLDQQCDPQTLPQQFGT
V-SGGIYEDSYASHGPMSLGELELEPNSNLVLPTTLLT-ARENDVNLLVAAE--------
--------------------EFSQYPQK--QKQNVKQVEHK---PEQS-YLRIRNKCDIA
PSQ-QQ------------------------------------------------------
------------------------------------------------------------
---------------

---------------------------------------------------MPARRLGEV
VSLNHGDNLAFLKHEL------PC-VPPALP-ANKRLSVRTGTS-LNGTSRGSSDLTSAR
NFHQPPL-E----NSAVSE---SDFSKDAVVQG--FSLDKTEESNKQKA

PF15324 // ENSGT00390000012397_0_Domain_2 (170, 1646)

NDI--LISQYT
MGQKDAIRTVLKQKA---------------------------------------------
-----QS------MPVFKEVKVHLLEDAVTEKDVV-TQETKTSPSGIDSATTVAAATAAA
IATAAPLIKVQSDLEAKVNSVTELLNKLQETDKHLQRVTEQQTNIRNK-QEKLHCH----
-DHEKQMNVFMEQHIRHLEKLQQQQIDIQTHFISAALKTSSF---QPASMPSSRAVEKYS
VKT-EHPNLGSSNLSTYNTFASKQA---------------------PIREVED----KQK
SPLETPAPRRFAPIPVSRGDELL----KRENPMEEKENMEMSGR------RGNVRLLEQI
LDNNDSLTRTMES-SDNSSLTRSKIGWNPEKRN---------RFPAYE----ELGAAKVT
MQKSNDVLHDLGQKKKETNDTDQPKESLNLL-----------------------------
----------------------RLA---DLPQNSV-KLQTTSATRSVLKDAEKILRGVQN
NKKVLEENLEAIIRAKDGAAMYSFINALSTNREMSEKNRIRKTVDEWIKTISAEIQDELA
RKDYEQKK---FDQKYQ--RTKKAQ-N----LGKDIKTNTQDKT----INKSVIPRKHPQ
KQIEEHFRNPPMR--SMPASSLQK-ERKEGLLKTNPVIKDEDYM-LQVYGKPVYQGHRST
LKKGPYLRFNSPSPKSIKPQRPKVIERVKGTKVKSIRTQTDIYATKPMKMDSKVKHSITT
-LPHGD-QQYLFSPSREMPTFSGALEGHLIPMAILLGQTQSNSDSMPSTGVIVSKPHPIT
VTTSIPP---SSQKTETGVKKPNIAVVEMKSEKKDPPQLTVQVLPSVDIDSISNGSADVG
SPL-LSP---KEAC-LPPLQTWIQAPEIMKVDEGEVKLPGTNFDEVIDVIQEE-EEHDEI
PD-SEPVLEFNRSVKVDATKYNGPPFPPVASTLQP--TADILDKVIERKETLE--NSLIR
WVEQEIMSRIISGLFPIQQ-HAIPDVSVS-VSEASEPLTSDIVEGTSSGALQLFVDAGVP
VNSDMISHFVNEALAEIIAVMLGDRETKKQGPAATSASGDVSTNETFL-RARVCTPVATP
QPTPPCSPSS----PPKEQVLVKTPDSSPCDSAHDVAFPVDEVFAEN----GSEMPAITP
FTTPAVTPVATPPPA--AALTP-TLSEISIDKVKVLGPELPKPWGNGDLPLEEENPSS-L
QE----EHLHPKAIV-MSVAKDEEPES-MDFPAQPAPPE-PVPLTPFSASTKAPSPSQTP
NSGSSTLESTLS-V--TETETLVRTISEGEILCSYGKKLASK--ILGDG--GLCLTNLND
SLSSTLRDALEMEDDPPSEGQVT---------TDTILSLHAKQNQESLVFQQAVYHS--E
DLENSVGELNEGQRPRPV--AAKNILSEHP-PWRQQP-VTNAESLGLQCDSKPLSQQFNT
V-SGGIYADEFASHGPMSLKELELHPNFNRVLPTTLLT-AQENDIILPVAAG--------
--------------------DFSQYQQQK-KDQDVKQVEYK---STESCLIHVRSKPDIS
PSQ-QA-LP--DDTDRTHIEPN-GYLTSVFTGGKAATHVTLQMPP--------AKMSVML
PSMNREDCSQPLNMGMVQG--------------------------DTESSGTDTF-----
---------------

----------------------------MKNVEFS--------LERGQRLKMPARKLREI
VSPNQGNKLAVVEDEL------PR-VPPALA-ANKRLAVETRTS-SNGTLCGSLDLTSAR
LYHQPLL-E----SPPASKK--SDFSKDAVVRQ--LPLNKTEENNAPKA

PF15324 // ENSGT00390000012397_0_Domain_2 (170, 1644)

NDI--FISQYT
MGQKDALRTVLKQKA---------------------------------------------
-----QS------MPVFKAVKVHLFEDTSTEKNTV-AQETETPPNRIDSATTVAAATAAA
IATAAPLIKVQSDLEAKVNCVGELLTKLQETDKQLQRVTEHQASVQSK-QEKVHCH----
-DHDKQMNAFMEQHIRHLEKLQQQQIDIQTHFIDAALKASSL---Q-LGMSTSRAVGKYS
GKL-GSPSVGS-SVFSHNTFVSKRV---------------------PLS--EDTDFDGQK
SPLETPAPRRFAPVPVSRDGKIT----KRESPTEEKENMEMNSP------KGNVRLLEQV
LNSNECLTRKTES-SDITSLTQPKMGWNLEKRDSTETLHSQ-IFPSSE----ERGTAQVP
VPKYNDVVHDLGQKK-QASDMLQIKQSPVTL-----------------------------
----------------------RLS---DHPHNPA-LLQTT-NTRSVLKDAAKILRGVQN
NKKVLEENLEAIVRAKDGAAMYSFINALATNREMSEKIRIRKQVDEWIKIISAEIQDELM
RKDYEQKR---FDPKNQ--RNKKAL-T----MSRDIKANNQEKT----VNRSVIPRSHYQ
KQTQEQFTSPPVR--NLPASGPQK-ER-SGLLKSATTLQDEDYM-LQIYGKPVYQGHRST
LKKGPYLRFSSPSPKA-KPQRPRVIELVKGTKVKSAKTQTDFHAASRMKMDSKIQHPITA
-LPHAD-QQYMVSPSREMPTVSGTLEGHLIPMAILLGQTQSNSDSMPPAGVTVNKPRPVT
VTTSIPP---ASRKGNAGVKKPNVAIVEMKSEKKDPPQLSVQILPSVDIDSVSYSSTDGA
SSP-PSP---KEAS-LPPLHTWIQTPDFMKVDEEEVPLPGTNFDEVIDVIQEE-EKRDEI
PECSAPMLEFNRSVKVVPTKYNGPSFPPVVSAYHP--TTDILDKVIERKETLE--NSLIQ
WVEQEIMSRIISGLFPLQQ-QARLDASVS-VSEASEPSASDIVAGTSSGALQRMVDARVP
VNSDMVSHFVNEALTETIAVMLADREAERQRAAATSVPGDLSGTETNL-LARVCAPVATP
QPTPPCSPS-----PVREHVRVKTPDSSPCESDPDAASSIKEIRVEK----GSDMPAVML
VSTPTRTPVATPPPAA--ALTP-TLSETSIDKLKLSSPELPKPWDSGDLPLDEENPNS-L
QE----L-PHPRAVV-M-SVANEEPES-VDFSAQPAPPE-PAPSAPLPEGTKAPSLQRVP
SSGSSTLENTLS--TVTETETLDRHISEGEILFSCGQNLATK----RPG--DLFLMNIND
SLSSTLQDALEMEDDPPSEGQVI-RRPHKKRHEDAIVALLTKQQRELLVSQQE------E
DLDNSVGELSEGQRLVLKA-A-EDISAGPS-GQMLPP-TSPAEPSYQHADPRLVLQQSDM
A-SGNICEDLCASHGPMSLRELELQPDSNLILPITHTT-TAVSDGNLPEAAE--------
--------------------DFSQYQQK--QDSDIKQVEHK---PIQRHLTSVRNKPDST
LSQH--------------------------QGGPADLLLIAHVSP--------ARMSVTL
PSANLEDCSQSLST--------------------------SSMHGGTESSGTDTF-----
---------------

----------------------------MKTCEFS--------LERGRRVKMPARRLREV
VSPNQGGNLDVVEDEL------PC-VPPALS-ANKRLAVGMRTS-SNGTSYGSLDLTSAR
KHHQLLS-E----NPTVSNK--SDFSKDAIVPR--LPLNKTEENRTQKA

PF15324 // ENSGT00390000012397_0_Domain_2 (170, 1646)

NDI--FISQYA
MGQKDALRTVLKQKV---------------------------------------------
-----QS------VPVFKAVKVHLLEDTSMEKNAV-AQETETSPNRIDSATTVAAATAAA
IATAAPLIKVQSDLEAKVNSVAELLNKLQETDKQLQRVAEHQTSIQNK-QEKLHCH----
-DHEKQMNVFMEQHIRHLEKLQQQQIDIQTHFIDAALKANSL---QPVGTPPSGAGGKHS
GKP-AHPNLGS-SVSSHNTFVSKQV---------------------PLREDEDTGFDVQK
SPLETPAPRRFAPVPVSKDGKIS----KRENPIEEKENMEMSSP------KGNVKLLEQI
LNTNDSLTRKSES-SDMTSLSRSKTGWSSEKRDSIETLHSQ-RFPSSE----ELGTAKVA
MQKYNDDVHDLGQKKKQTNDMLQVKQSPIIL-----------------------------
----------------------KFS---DLPEKPV-KLQTT-NTRSVLRDAEKILRGVQN
NKKVLEENLEAIIRAKDGAAVYSFINALSTNREISEKIRIRKQVDDWIQIISAEIQDELT
KKDYEQKR---FGSKNQ--RSKQTL-T----MSGDFKANIQDKT----VNKSVISRRRCQ
KQIQEQFRSVPGR--NMYALGSQR-ERKEGLSRSTTVLQDEDY----IYGKPVYQGHRST
LKKGPYLRFTSPSPKA-KPQRPKVIELVKGTKVKSARTQTDFDATKPMKIDSKIQYPITT
-VPRGD-QQYLFSPNRQVPNVSGALEGHLIPMAILLGQTQSNSDSAPAAGVMVNKPHSVA
VTTFIPP---SSRKGEAGVKKPNIAVVEMKSEKKDPPQLSVQMLPSLDIDSISYSSVDGV
SPP-PSP---KEAS-LPPLPTWIQIPEFMKVDKEEAKLPGTNFDEVIDVLQEE-DQRDEI
PECSAPVLEFNRSVKVIPTEYNGPSFPPVVSNFHP--TTDILDKVIERKETLE--NSLIQ
WVEQEIMSRIISGLFPLQQ-QARLDDSVS-ISEASEPPASDVVVGTSSGALQLFIDAGVP
VNSDMISQFVHEALAETIAVMLGDREAKKQGPVAKSVSGNTSTNETNL-PVRVCTPVATP
QPTPPCSPP-----PPQEHVLVNTPDSSPCDSDQDVASSIKEICTEK----GSDIPAITL
VSTPTVTPVNTPPPAE--VLTP-TLSEISIDKLKLSSPDLPKPWDSGDLPLDEENPNS-L
QE----L-LHPRAIV-MSVAKDEEPGS-VDFPALPAAPE-PAPPTPLPEGTKPPSPQQNP
SSSSSTQENSLS-ITVTETETLDRHISEGEILLSCGQNLASK--VLGNG--DLYLMNVND
SLSSTLHDALEMEDDPPSEGQVI-RRPHKKLHANMILSLFTKQEQELLISQQA------E
DLDNSVGELSEGQRLVLTA-A-EDILAGPS-ICVPQP-TTSAEPSDQQADPGVLLQLSDM
A-SGDICEDSRASHGPMSLRELELQPCPNLVFPITHMA-TKGNGANLPGAAE--------
--------------------GFSQYQQK--HEPDIKQVEHK---PVQSHLTCVRNKSDSS
LSQQ--------------------------QGGQTAPLFTAHMPP--------ARVSVTL
PSANLEDCSQPLST--------------------------SSIQGDEDSSGTDTF-----
---------------

---------------------------------------------------MPAKRLREV
VSQNHGDHLVLLKDEL------PC-VPPALS-ANKRLPVGTGTS-LNGTSCGSSDLTSAR
NCHQPLK-E----NPMVSE---SDFSKDVAVQV--LPLDKIEENNKQKA

PF15324 // ENSGT00390000012397_0_Domain_2 (170, 1649)

NDI--FISQYT
VGQKDALRTVLKQ-----------------------------------------------
---KAQSM------PVVKEVKVHLLEDAGIEKDAV-TQETRISPSGIDSATTVAAATAAA
IATAAPLIKVQSDLEAKVNSVTELLSKLQETDKHLQRVTEQQTSIQSK-QEKLHCH----
-DHEKQMNVFMEQHIRHLEKLQQQQIDIQTHFISAALKTSSF---QPVGMPSSRAVEKYS
VKP-EHPNLGSCNASLYNTFASKQA---------------------SLKEVEDMSFDKQK
SPLETPAPRRFAPVPVSRDDELS----KRENLLEEKENMEVSCH------RGNVRLLEQI
LNNNDSLTRKSES-SNTTSLTRSKIGWTPEKTN---------RFPSCE----ELGTTKVT
LQKSDDVLHDLGQKEKETNSVVQPKESLSML-----------------------------
----------------------KLP---DLPQNSV-KLHTTNTTRSILKDAEKILRGVQN
NKKVLEENLEAIIRAKDGAAMYSLINALSTNREMSEKIRIRKTVDEWIKTISAEIQDELS
RTDYEQKR---FDQKNQ--RTKKGQ-N----MTKDIRTNTQDKT----VNKSVIPRKHSQ
KQIEEHFRNLPTR--GMPTSSLQK-ERKEGLLKATTVIQDEDYM-LQVYGKPVYQGHRST
LKKGPYLRFNSPSPKS-KPQRPKVIERVKGTKVKSIRTQTDSYATKPMKIDSKMKHSVPM
-LPHGD-QQYLFSPSREMPTFSGTLEGHLIPMAILLGQTQSNSDTMPPAGVIISKPHPVT
VTTSIPP---SSRKVETGVKKPNIAVVEMKSEKKDPPQLTVQVLPSVDIDSISNGSTDVG
SPL-SSP---KEAS-LPPVQAWIKTPEIMKVDEEEVKFPGTNFDEIIDVVQEE-EKCDEI
PD-SEPILEFNRSVKADSTKYNGPPFPPVASTFQP--TANILDKVIERKETLE--NSLIQ
WVEQEIMSRIISGLFPIQQ-QIAPNISVS-VSETSNPLTSDIVEGTSSGALQLFVDAGVP
VNSDVINHFVNEALAETIEVMLGDREAKKQGPVATGVSGDASTNETYL-PARVCTPLATP
QPTPPCSPSS----PTKECVLVKTPDSSPCDSDHDMTFPVKEIYAEK----GDDMPAIML
VKTPTVTPTTTPPPAV-AVFTP-TLSDISIDKLKVSSPELPKPWGDGDLPLEEENPNS-P
Q-----EELHPRAIV-MSVAKDEEPES-MDFPAQPPPPE-PVSFMPFPAGTKAPSPSQMP
GSDSSTLESTLS-VTVTETETLDKPVSEGEILFSCGQKLAPK--ILEDV--GLYLTNLND
SLSSTLHDAVEMEDDPPSEGQVI-RMPHKKFHADAILSVLAKQNQESAVSQQAVCHS--E
DLENSVGELSEGQRPQLTA-AAENILMGHS-LCMQPP-VTNVQPLDQQCDPKPSSRQFDA
V-SGSIYEDSCASHGPMSLGELELEPNSNLVLPTTLLT-LQENDVNLPVAAE--------
--------------------DFSQYQQK--RNQDVKQVEHK---PSQS-YLHVTNKSDIA
PSQ-QQVSP--GDMDQTQNELN-PYLTCVFTGGKAMPLSA----SQM---PPAKVSMTLP
SV-----NLE-----------DCSQS--------LSIS--------TMQEDVESSGADTF
---------------

----------------------------MKGSEVS--------PEERKRLKMPPRRLREV
VSPNQGSNLALLKDEL------PC-LPPALP-ANKRLPVGVGTS-RSRTLPGSSDLPSAR
NNHQPLL-E----NPTASE---SDFSKDVAVQE--LHLDKAEDSSRKEA

PF15324 // ENSGT00390000012397_0_Domain_2 (170, 1649)

DDI--FISQYS
VGQKDALRTILKQKA---------------------------------------------
-----QS------VPAFKEVKVQLLEDTGTEKGAA-PQEARVSPSGIDSATTVAAATAAA
IATAAPLIKVQSDLEAKVNSVTELLNKLEETDKHLKRVTEQQTSIQNK-QEKLHCH----
-DHEKQMNVFMEQHIRHLEKLQQQQIDIQTHFISAALKTHAF---PPAGTLASRAMEKHS
RES-GRPHLSSSTPSAHIPFASKPA---------------------TLRKVEDTDFDEQK
SPLETPTPRRFAPIPVSRDGEIS----KRENLIEEKENMEKSNH------RGNTRFLEQI
LNNNDSSTRKSES-SDITSLSRSKVGWNPERRDGFEIVSSQ-RFPSSE----EQETANVA
KQKPNDVLHDLGQKRKETSGVLQ-------------------------------------
--------------------------------NSA-KLQTTNTMRSVLKDAEKILRGVQN
NKKVLEENLEAIIRAKDGAAMYSFINALSTSREMSEKIRIRKTVDEWIKVISAEIQDELA
RKDYEQRR---FDQKNQ--RTKKAQ-N----MSKDMKVNKQDKT----VNKSVILRK-PQ
KQVEDYLRSPSMR--SMATSSLQK-ERKEGPLKSSTVIQDEDHM-SQVYGKAVYQGHRST
LKRGPYLRFNSTALKS-KPQRPKVIEQVKGTKVKSIRTQTDFHATKPTKTDSKMQQSITA
-LPHSE-QQYLFSPSREMPTFSGTLEGHLIPMAILLGQTQSNSDSLPPAGVMVHKPHPVT
VTTSIPP---ASRKGEPGVRRPNIAVIEMKSEKKSPPQLTVQVLPNVDIDSPLNGSTSAS
SP-LPSP---EGAP-LPPLRTCIQTPEFMKVDEEEVKFPGTNFDEVIDVIQEE-EKCDEI
PECSEPMLEFNRSVKVASTRYNGPPFPPVVSTSQP--TADILDKVIERKETLE--NHLIQ
WVEQEIMSRIISGHFPVPS-QTRLPASVS-VSEASEPSTPDIVEGTCGGALQLFVDAGVP
VSSDTIRCLVNDALAETIAGMLGDRESKKQGPGAADVPADVSTSETPL-LTRICTPVATP
QPTPPCSPLA----PPEECMLVKTPDSSPCGSYHDVAFVMKEISAKNEKSLGNDMPAITH
VNTPAVTPAATPPPA--AALTP-SLSEISIDKLKISCLELPKPWGDRDLPLEEENPHC-L
QE----ELPYPRALV-MSVAKDEEPES-VDSPAQPAPAE-PVPFTPLPAGTEAPASLRMP
SSSSSTLESTLS-ITVTDAETLDRPISEGEVVFSCGQRLAPK--MLGGG--ELYLTTLND
SFSSTLHDALEMEDDSPSEGQVI-RISHKKFHADALLPLLAKQNQELLVSQQAVCHS--E
DLENSMGELSEGQRPRLTA-AAEHILLGQS-LCMQQC-IVNEESVGQPCDPKPLFQQSDI
V-SGGIYEDSCASHGPMSLGELELQTNSNTVLPTALLK-TQGSGACLLEAAE--------
--------------------DVFQNQQN--QDQNVKQVEHK---PVQSRLICVRNISDIS
PS----------------------------RGGEAVPCFTSQPSP--------ARMCVTL
PAVNLEDCSPSQSV--------------------------SAIQGDTGSSGADTF-----
---------------

-----------------------VN-NNMKGSEVS--------LEKKKRIKMPAKRLREV
VSQNHGDHLVLLKDEL------PC-VPPALS-ANKRLPVGTGTS-LNGPSCGIPYLFKFP
DSS--------------------------LY-----RCLKTDPVSRENANDI--FISQYT
VGQKDALRTVLKDGVSL-------CYGVITTHCTLYL---------LRLMRSSHLSLLSN
WDY

PF15324 // ENSGT00390000012397_0_Domain_2 (244, 1649)

RAQSM------PVVKEVKVHLLEDAGIEKDAV-TQETRISPSGIDSATTVAAATAAA
IATAAPLIKVQSDLEAKVNSVTELLSKLQETDKHLQRVTEQQTSIQSK-QEKLHCH----
-DHEKQMNVFMEQHIRHLEKLQQQQIDIQTHFISAALKTSSF---QPVSMPSSRAVEKYS
VKP-EHPNLGSCNASLYNTFASKQA---------------------SLKEVEDMSFDKQK
SPLETPAPRRFAPVPVSRDDELS----KRENLLEEKENMEVSCH------RGNVKLLEQI
LNNNDSLTRKSES-SNTTSLTRSKIGWTPEKTN---------RFPSCE----ELGTTKVT
LQKSDDVLHDVGQKEKETNSMVQPKESLSML-----------------------------
----------------------KLP---DLPQNSV-KLHTTNTTRSILKDAEKILRGVQN
NKKVLEENLEAIIRAKDGAAMYSLINALSTNREMSEKIRIRKTVDEWIKTISAEIQDELS
RTDYEQKR---FDQKNQ--RTKKGQ-N----MTKDIRTNTQDKT----VNKSVIPRKHSQ
KQIEEHFRNLPTR--GMPTSSLQK-ERKEGLLKATTVIQDEDYM-FQVYGKPVYQGHRST
LKKGPYLRFNSPSPKS-KPQRPKVIERVKGTKVKSIRTQTDSYATKPVKKDSKMKHSVPM
-LPHGD-QQYLFSPSREMPTFSGTLEGHLIPMAILLGQTQSNSDTMPPAGVIISKPHPVT
VTTSIPP---SSRKVETGVKKPNIAVVEMKSEKKDPPQLTVQVLPSVDIDSISNGSTDVG
SPL-CSP---KEAS-LPPVQAWIKTPEIMKVDEEEVKFPGTNFDEIIDVIQEE-EKCDEI
PD-SEPILEFNRSVKADSTKYNGPPFPPVASTFQP--TANILDKVIERKETLE--NSLIQ
WVEQEIMSRIISGLFPIQQ-QIAPNISVS-VSETSDPLTSDLVEGTSSGALQLFVDAGVP
VNSDMINHFVNEALAETIEVMLGDREAKKQGPVATGVSGDASTNETYL-PARVCTPLATP
QPTPPCSPSS----PTKECVLVKTPDSSPCDSDHDMAFPVKEIYAEK----GDDMPAIML
VKTPTVTPTTTPPPAV-AVFTP-TLSDISVDKLKVSSPELPKPWGDGDLPLEEENPNS-P
Q-----EELHPRAIV-MSVAKDEEPES-MDFPAQPPPPE-PVSFMPFPAGTKAPSPSQMP
GSDSSTLESTLS-VTVTETETLDKPISEGEILFSCGQKLAPK--ILEDV--GLYLTNLND
SLSSTLHDAVEMEDDPPSEGQVI-RMPHKKFHADVILSVLAKENQESAVSQQAVCHS--E
DLENSVGELSEGQRPQLTA-AAENILMGHS-LYTQPP-VTNAQSLDQQCDPKPLSRHFDA
V-SGSIYEDSCASHGPMSLGELELEPNSNLVLPTTLLT-LQENDVNLPVAAE--------
--------------------DFSQYQQK--RNQDVKQVEHK---PSQS-YLHVTDKSDIA
PSQ-QQVSP--GDMDQTQNELN-PYLTCVFTGKSFTLKKV----SCIGKLGPRGFVIQII
PS-----PRWESNATLRFTDAPCQGVHDAALSEPRGLLSVSEH--QHDAGGRGVFGSRYL
LNGKRQPAQCLCH--

------------------CGTSFVT-NNMKGSEVS--------LQKKKRVKMPAKRLPEV
VSQNHGDHLVLLRDTL------PC-VPSALS-ANKGLPAGTGTR-VNGTSPGMSFHVV--
------------------------------FQC--LK---TDPVSQENQNDI--LISQYT
TGQKDALRTVLKQNVSLCCPGWSAWSGAFTTHCSLYLLRL---------MRSSCLSLPSN
WDY

PF15324 // ENSGT00390000012397_0_Domain_2 (244, 1649)

KAQSM------PVFKEVKVHLLEDAGIEKDAV-TQETRISPSGIDSATTVAAATAAA
IATAAPLIKVQSDLEAKVNSVTELLSKLQETDKHLQRVTEQQTSIQSK-QEKLHCH----
-DHEKQMNVFMEQHIRNLEKLQQQQMDIQTHFISAALKTSSF---QPVSVPSSRAVEKYF
VKP-EHPNLGSCNPSSYNTFASRQV---------------------PLKEIEDKSFDKQK
SPLETPAPRRFAPIPVSRDDELS----KRENLLEEKENMEVSCH------RGNVRLLEQI
LNTNDCLTRKSES-SNTTSLTRSKIGWNLEKTD---------RFPSYE----ELGTAKVT
VQKSDDVLHDLVQKKKETNGMVQPKESLSML-----------------------------
----------------------KLA---DLPQNSV-KLQTTNTTRSVLKDAEKILRGIQN
NKKVLEENLEAIIRAKDGAAMYSLINALSTNREMSEKIRIRRTVDEWIKTISAEIQDELS
RTDYEQKR---FDQKNQ--RTKKAH-N----MTKDIRTNTQDKT----VNKSVIPRKHSQ
KQIEEHFRNLPMR--GMPAASTQK-ERKEGLLKASTVIQDEDYM-LQVYGKPVYQGHRST
LKKGPYLRFNSPSPKS-KPQRPKVIERVKGTKVKSIRTQTDFYATKPIKMDSKTKHSIPM
-LPHGD-QQYLFSPSREMPTFSGTLEGHLIPMAILLGQTQSNSDSMPPAGVIVSKPHPIT
VTTSIPP---SSRKVETGVKKANIAVVEMKSEKKDPPRLTVQVLPSVDIDSISNGSADVS
SPL-PSP---KEAS-LPPVQTWIKTPEIVKIDEEEVKFPGTNFDEIIDVIQEE-EKCDEI
PD-SEPILEFNRSIKADSTKYNGPPFPPVASTFQP--TADILDKVIERKETLE--NNLIQ
WVEQEIMSRIISGLFPIQQ-QIAPSISVS-VSETSEPLTSDIVEGTSSGALQLFVDAGVP
VNSDMIKHFVNEALAETIAVMLGDREPKKQGPVAASVSGDASTNEMYL-PARTCTPLATP
QPTPPRSPSS----SPKECVLVKTPDSSPCDSDYDMAFPVKKVLAEK----GDDMPAIML
ANTPAVTPTTTPPPA--AVFTP-TLSEISVDKLKVSSPELPKPWGDGDLPLEGENPNS-P
Q-----EELHPRAIV-MSVAKDEEPES-MDFPAQPPPPE-PVPFMPFPAATKAPSPSQMA
GSDSSTLESTLS-VTVTETETLDKPISEGEILFSCGQKLAPK--ILEDV--GLYLTNLND
SLSSTLHDSVEMEDDPPSEGQVI-RMPNKKFHADAILSLLAKQNQESAVLQQAAYHS--E
DLENSMGELSEGQRPQLTA-AAENILMGHS-VYIQPP-VTNAESLDQQCDPKPLPQQFGT
V-SGGIYEESYASHGPMSLGELELEPNSNLVPPTTLLT-ARENDVNLPVAAE--------
--------------------DFSQYPQK--RNQNVKQVEHK---PEQS-YLRIRSKCDIA
PSQ-QQ-----GDMDRTQIEPN-LYLTSVFTGIFLFFFLILPFVFLYSSFLTLPHIFVII
AILTSPLCRWESSATLRFTDAPCQDVRDAALREPQGLLSVSKH--QHDAGGHGVFRARYL
LNRKREPAHCLCHRF

----------------------------MKGSEVS--------LKKQNRLKMPARRLREV
HFASS--KWCLLSNKL------KAY------------------------L-------V--
---------------SFSFHIPKDFSKDVAVQE--LPLDKTEDR-----

PF15324 // ENSGT00390000012397_0_Domain_0 (170, 389)

NDV--FISQYS
VGQKDALRTILKQKA---------------------------------------------
-----QS------IPIFKEVKVHLLDDAGVEKVAA-PPEARGSPSGIDSATTVAAATAAA
IATAAPLIKVQSDLEAKVNSVTELLNKLQETDKHLKRVTEQQTSIQNK-QEKLYCH----
-DHEKQMNVFMEQHLKHLEKLQQQQIDI

ENSGT00390000012397_0_Linker_0_3 (389, 468)

QVAEKCLLLMVY-----------------VYS
V-----------------S---------------------------F

PF15324 // ENSGT00390000012397_0_Domain_3 (468, 555)

CVKVEDTYFDEQE
SPLETPAPRRFAPGPVSRDGEMP----KRENPMEEKENMEKSDY------KV--------
LNGAVALIRKEQN-

ENSGT00390000012397_0_Linker_3_2 (555, 628)

SDKNICLQRNVEGSP-------------------------------
-----------------------PYLI

PF15324 // ENSGT00390000012397_0_Domain_2 (628, 1204)

SDNV-----------------------------
----------------------ELA---DLPQSSC-KLQTT-NTRSVLKDAEKILRAVQN
NKKMLEENLEAIIRAKDGAAMYSFINALSTNREITEKIRIRKTVDEWIKAISAEIQDELA
RKDFEQRR---FAQKNQ--RTQKAQ-I----MSKDIKANTQDKT----XXXXXX-XKKPQ
KQVEDYFRSPPAR--SMAVSSLQK-ERKEGPLKSPTMIRDEDYM-SQVYGKAVYQGHRST
LKRGPYLRFNSTSLKS-KPQRPKVIEQVKGEERNFL-----------CFTDSKMQHSIPA
-LPHGE-QQYVFSPSREMPTFSGTLEGHLIPMAILLGQTQSNSDSLPPAGV-VHKLHPVT
VTTSIPP---SSRKVETGVKKPNIAVVEMKSEKKDPPQLTVQVLPSVDIDSVSNSSAPSS
LPFLSSP---EG-APFPLMRMCTQSPEFMKANEEEVKFPGSNFDEVIDVIQDE-EKCDEI
PEYSEPILEFNRSVKVVSTKYNGPPFPPVLSTAQP--TTDILDKVIERKNTLE--NNLIQ
WFR

ENSGT00390000012397_0_Linker_2_5 (1204, 1242)

LQVCF-----------------------SPTYSENLLF

PF15324 // ENSGT00390000012397_0_Domain_5 (1242, 1310)

VVEGTCGGALQLFVDAGVP
VSSGTIRRLVNDALAETIAGMLGDRESKKESPVAAGVPGDVSTSETLL-LVGSW------
----------------------------------LLTFIFFFLSFKKERSVGQDIPAVTL
VNTPAVTPTATPPLAA--ALTP-TLSETSIDKLKISSPELPKPWGDRDLPLDEXXXXXXX
XXXXXXXXXXXXXXXVMSVAKDEEPRS-MDSPAPLTPAE-PPPLTQLPVCAEVPASLQVL
SSSSSTLESTLS-LTITGVETLDRPISEGEIVFSCGQRLAPR-----SG--ELYLTNLND
SFSSTLHDALEM------------------------------------------------
DLENSVGELSEGQRPKLTV-AAKHVFLGQA-LCMQQR-ITSAENPI-----------YEQ
NIKSGICEDSCASRGPMSLGELELQPXXXXXXXXXXXX-XXXXXXXLPEAAE--------
---------------------VCQNQQK--QDQDVKQVEHM-------------------
--------------------------FLLWTGGETVPCFTSQPSP--------ARMCVTL
PAVNLEACSPSLSA--------------------------STIQGDAGSSGTDSF-----
---------------

------M--------FWVMGTCFVT-NNMKGSEVS--------LEKKKRIKMPAKRLREV
VSQNRGDHLVLLKDDL------PC-VPPALS-ANKRLPVGTGTS-LNGTSRGSSDLTSAR
NCHQPLK-E----NPMVSE---SDFSKDDAVQV--LPLDKIEENNKQKANDI--FISQYT
MGQKDAVRTVLKQKQCLTLSHMLECSGVITTHCTLYL---------LRLMRSFHLSLLSN
WDY

PF15324 // ENSGT00390000012397_0_Domain_2 (244, 1649)

RAQSM------PVVKEVKVHLLEDAGIEKDAV-TQETRISPSGIDSATTVAAATAAA
IATAAPLIKVQSDLEAKVNSVTELLSKLQETDKHLQRVTEQQTSIQRK-QEKLHCH----
-DHEKQMNVFMEQHIRHLEKLQQQQIDIQTHFISAALKTSSF---QPVSMPSSRAVEKYS
VKP-EHPNLGSCNASLYNTFASKQA---------------------SLKEVEDMSFDKQK
SPLETPAPRRFAPVPVSRDDELS----KRENLLEEKENMEVSCH------RGNVRLLEQI
LNNNDSLTRKSES-SNTTSLTRSKIGWTPEKTN---------RFPSCE----ELGTTKVT
LQKSDDVLHDPGQKEKETNSMVQPKESLSML-----------------------------
----------------------KLP---DLPQNSV-KLHTTNTTRSVLKDAEKILRGVQN
NKKVLEENLEAIIRAKDGAAMYSLINALSTNREMSEKIRIRKTVDEWIKTIS----DELS
RTDYEQKR---FDQKNQ--RTKKGQ-N----MAKDIRTNTQDKT----VNKSVIPRKHSQ
KQIEEHFRNLPMR--GMPASSLQK-ERKEGLLKATTVIQDEDYM-LQVYGKPVYQGHRST
LKKGPYLRFNSPSPKS-KPQRPKVIERVKGTKVKSIRTQTDSYATKPMKIDSKMKHSVPM
-LPHGD-QQYLFSPSREMPTFSGTLEGHLIPMAILLGQTQSNSDTMPPAGVIVSKPHPVT
VTTSIPP---SSRKVETGVKKPNIAVVEMKSEKKDPPQLTVQVLPSVDIDSISNGSTDVG
SPL-SSP---KEAS-LPPVQAWIRTPEIMKVEEEEVKFPGTNFDEIIDVIQEE-EKCDEI
PD-SEPILEFNRSVKADSTKYNGPPFPPVASTFQP--TANILDKVIERKETLE--NSLIQ
WVEQEIMSRIISGLFPIQQ-QIAPNISVS-VSETSEPLTSDIVEGTSSGALQLFVDAGVP
VNSDVINHFVNEALAETIEVMLGDREAKKQCPVATGVSGNASANETYL-PARVCTPLATP
QPTPPCSPSS----PTKECVLVKTPDSSPCDSDHDMAFPVKEICAEK----GDDIPAIML
VKTPTVTPTTTPPPAV-AVFTP-TLSDISIDKLKVSSPELPKPWGDGDLPLEEENPNS-P
Q-----EELHPRAIV-MSVAKDEEPES-MDFPAQPPPPE-PVPFMPFPAGTKAPSPSQMP
GSDSSTPESTLS-VTVTETETLDKPVSEGEILFSCGQKLAPK--SKL--------IYYGN
PLSN---TFLFKEDDPPSEGQVI-RMPHKKFHADAILSVLAKQNQESAVSQQAVCHS--E
DLENSVGELSEGQRPQLIA-AAENILMGHS-LYMQPP-VTNAQSLDQQCDPKPLSRQFDA
V-SGSIYEDSCASHGPMNLGEMELEPNSNLVLPTTLLT-LQENDVNLPVAAE--------
--------------------DFSQYRQK--RNQDVKQVEHK---PSQS-YLHVTNKSDIA
PSQ-QQ-----GDMDQTQNELN-PYLTCVFTGKSFTLKKV----SCIGKLGPWGFVIQII
PS-----PRWESNATLRFTDAPCQDVHDAALSEPRGLLSVSEH--QHNAGGRGVFRGRYL
LNGKRQPAQCLCH--

-----------------------VT-NHMKGSEVS--------LQKKKRVKMPAKRLREV
VSQNHGDHLVLLKDEL------PC-VPPALS-ANKRLPVGTGTR-VNGTSHGSSDLTSAG
NCHQSLL-E----NLMVSE---SNFSKDVAVQV--LPLDKIEENNKQKENDI--FISQYT
TGQKDALRTVLKQ--------KLECNGMILAHCSLYRLGS------SNSPRFSCLSLPSN
WDYRCDSLCPARIILSY

PF15324 // ENSGT00390000012397_0_Domain_2 (258, 1649)

NEVKVHLLEDAGIEKDAV-TQETRISPSGIDSATTVAAATAAA
IATAAPLIKVQSDLEAKVNSVTELLSKLQETDKHLQRVTEQQTSIQSR-QEKLHCH----
-DHEKQMNVFMEQHIRNLEKLQQQQIDIQTHFISAALKTSSF---QPVSVPSSRAVEKYF
VKP-EHPNLGSCNPSSYNTFASRQA---------------------PLKEIEDMSFDKQQ
SPLETPAPRRFAPIPVSRDDELS----KRENLLEEKENMKVSCH------RGNVRLLEQI
LNNNDSLTRKSES-SNTTSLTRSKIGWNPEKTD---------RFPSSE----ELGTAKVT
VQKSDDVLHDLGRKKKETNGMVQPKESPSML-----------------------------
----------------------KLA---DLPQNSV-KLQTTNTTRSVLKDAEKILRGVQN
NKKVLEENLEAIIRAKDGAAMYSLINALSTNREMSEKIRIRRTVDEWIKTISAEIQDELS
RTDCEQKI---FDQKNQ--RTKKAH-N----MTKHIRTNTQDKT----VNKSVIPRKHSQ
KQIEEHFRNLPMW--GMPAASIQK-ERKEGLLKASTVIQDEDYM-LQVYGKPVYQGHRST
LKKGPYLRFNSPSPKS-KPQRPKVIERVKGTKIKSIRTQTEFYATKPIKMDSKTKHCIPM
-LPHGD-QQYLFSPSREMPTSSGTLEGHLIPMAILLGQTQSNSDSMPPARVIVSKPHPVT
VTTSIPP---SSRKVETGVKKPNIAVVEMKSEKKDPPGLTVQVLPSVDIDSISNGSADVS
SPL-PSL---KEAS-LPPVQTWIKTPEIVKIDEEEVKFPGTNFDEIIDVIQEE-EKCDEI
PD-SEPILEFNRSIKADCTKYNGPPFPPVASTFQP--TADILDKVIERKETLE--NSLIQ
WVEQEIMSRIISGLFPIQQ-QIAPNISVS-VSETSEPLTSDIVEGTSSGALQLFVDAGVP
VNSDMINHFVSEALAETIAVMLGDREPKKQDPVAASVSGDASTNEMYL-PARMCTPLATP
QPTPPRSPSS----SPKECVLAKTPDSSPCDSDHDMAFPVKKVLAEK----GDDMPAIML
ANTPAVTPTTTPPPA--AVFTP-TLSEISIDKLKVSSPELPKPWGDGDLPLGEENPNS-P
Q-----EELHPRAIV-MSVAKDEEPES-MDFPVQPLPPE-PVPFMPFPAATNASSPSQMP
GSDSSTLESTLS-ITVTETETLDKPISEGEILFSCGQKLAPK--ILEDV--GLYLTNLND
SLSSTLHDAVEMEDDPPSEGQVI-RMPHKKFHADAILSLLAKQNQESAVLQQAVYHS--E
DLENSMGELSEGQRPQLTA-AAENILMGHS-LCMQPP-VTHAESLDQQCDPKPLPQQFGT
V-SGGIYEDSYASHGPMSLGELELEPNSHLVLPTTHLT-AGENDVNLPVAAE--------
--------------------DFYQYPRK--QNQNVKQVEHK---PEQS-YLHIRNKCDIA
PSQ-QQ-----GDMDQTQIEPN-LYLTS----------NVS----CIGKLGPWEI----I
SSPTSPLCRWESSATLRFTDAPCQDVRDTALSEPRGLLSVSEH--QHNAGGHGVFRARYL
LNGKREPAHCLCHRF

----------------------------MKNVEFN--------LERAERLKMPARRLREV
VSPNQGNKLPVVEDEL------PREVPPALS-ANKRLAVGTRTS-SNGTLCGSLDLTSAR
H--QPLS-E----NPPAG-P--KDFSKDAVVQR--LPLNKTEENNAQKA

PF15324 // ENSGT00390000012397_0_Domain_2 (170, 1644)

NDI--FISQYA
TGQKDALRTVLKQKA---------------------------------------------
-----QS------TPAFKAVKVHLLEDMSTEKNTV-AQDTETPPNRIDPATTVAAATAAA
IATAAPLIKVQSDLEAKVNSVGELLNKLQETDKQLQRVTEHQASIQHK-QEKLHCH----
-DHEKQMNVFMEQHIRHLEKLQQQQMDIQTHFIDAALKASSL---Q-FGLSSSRAEDKYS
GKP-QHPSV-----SSHNTFVSKQV---------------------PLS--EDTDFDGQK
SPLETPAPRRFAPVPVSRDGKVT----KRESSIEEKENMEMYSP------KGNVRLLEQV
LNSNECLTRKTES-SDITSLTQPKMGWNFEKRDSTETLHSQ-RFPSCE----DRGTAQVP
VQKYNDIVHDLSQKKKQTSDMLQVKQSPVTL-----------------------------
----------------------RLS---DHPHNPV-MPQTT-NTRSVLKDAAKILRGVQN
NKKVLEENLDAIVRAKDGAAVYSFINALATNREMSEKIRIRKKVDEWIKIISAEIQDELT
RKDYE-KR---FDPKNQ--RNKKSL-T----MSRDIKANNQDKT----ANRSIIPRSHYQ
KQTQEQFTSPPVR--SVPASAPQR-EK-NGLLKSTTTLQDEDYM-FQIYGKPLYQGHRST
LKKGPYLRFSSPSPKA-KPQRPRVIERVKGTKVKSARTQTDFHATPLTKTDSKAQHPITT
-LPHAH-QQCVLSPSREMPTVSGTLDGHLIPMAILLGQTQSNSDSIPPAGVLVSKPHPVT
VTTSIPP---SSRKVKAGVKKPNVAVVEMKSEKKDPPQLSVQILPSVDIDSISYSSTGGS
SPS-PSP---KEAS-PPPLHTWIQTPEFMKVDEEELPVPGTNFDEVIDVIQEE-EKRDEI
PECSAPMLEFNRSVKVVPTKYSGPSFPPVVSALRP--TTDILDKVIERKETLE--NNLIQ
WVEQEIMSRIISGLFPLQQ-QARLDASVS-VSEASEPSASDIVPGTSSGAFQLMVDAGVP
VNSDMISHFVNEALAETIAVMLADREAKKQGPAATRVSGDLSRNETNV-SARVYPPVATP
QPTPPCSPA-----PLKEHVFVKTPDSSPCESDQDVASSVKEIPVEK----GRNPVSLKV
VSTPTRTPVTTPPPAA--ALTPRTLSKISIDKLKFSSRNLPKPWDSGDASWDEENPNS-L
RE----T-SSPQGAVVMSVAIDEEPES-VASSAQPVPPE-PAPLAPHLEDTKAPSLQQIL
SSGSSTPENTLS--TVTETETLDRHISEGEILLSCGQNLATK----RNG--DLFLMNIND
SLSTTLQDALDMEDDPPSEGQVI-RRPHKKLHENAIISLLTKQEQELLVSQQA------E
DLDNSVGELSEGQRLVLKA-A-EDIPAGPL-VLMLQP-TLAAEPSDQHADPRLVLQQSDM
A-SGNICEDLYATHGPMSLRELELQRDSNLILPITHTT-TKVIDVNLPEAAE--------
--------------------DFSQYQQK--QDTDIKQVEHK---PIQRHLTGVRNKSDSS
LSQH--------------------------QGGPADPLFITHVSP--------ARMSVTL
PSANLEDHSQSLST--------------------------SSMHGSAESSGTDTF-----
---------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------

PF15324 // ENSGT00390000012397_0_Domain_2 (181, 1646)

MGQKDALRTVLKQKV---------------------------------------------
-----QS------VPVFKAVKVHLLEDTSMEKNAV-AQETETSPNRIDSATTVAAATAAA
IATAAPLIKVQSDLEAKVNSVAELLNKLQETDKQLQRVAEHQTSIQNK-QEKLHCH----
-DHEKQMNVFMEQHIRHLEKLQQQQIDIQTHFIDAALKANSL---QPVGTPPSGAGGKHS
GKP-AHPNLGS-SVSSHNTFVSKQV---------------------PLREDEDTGFDVQK
SPLETPAPRRFAPVPVSKDGKIS----KRENPIEEKENMEMSSP------KGNVKLLEQI
LNTNDSLTRKSES-SDMTSLSRSKTGWSSEKRDSIETLHSQ-RFPSSE----ELGTAKVA
MQKYNDDVHDLGQKKKQTNDMLQVKQSPIIL-----------------------------
----------------------KFS---DLPEKPV-KLQTT-NTRSVLRDAEKILRGVQN
NKKVLEENLEAIIRAKDGAAVYSFINALSTNREISEKIRIRKQVDDWIQIISAEIQDELT
KKDYEQKR---FGSKNQ--RSKQTL-T----MSGDFKANIQDKT----VNKSVISRRRCQ
KQIQEQFRSVPGR--NMYALGSQR-ERKEGLSRSTTVLQDEDY----IYGKPVYQGHRST
LKKGPYLRFTSPSPKA-KPQRPKVIELVKGTKVKSARTQTDFDATKPMKIDSKIQYPITT
-VPRGD-QQYLFSPNRQVPNVSGALEGHLIPMAILLGQTQSNSDSAPAAGVMVNKPHSVA
VTTFIPP---SSRKGEAGVKKPNIAVVEMKSEKKDPPQLSVQMLPSLDIDSISYSSVDGV
SPP-PSP---KEAS-LPPLPTWIQIPEFMKVDKEEAKLPGTNFDEVIDVLQEE-DQRDEI
PECSAPVLEFNRSVKVIPTEYNGPSFPPVVSNFHP--TTDILDKVIERKETLE--NSLIQ
WVEQEIMSRIISGLFPLQQ-QARLDDSVS-ISEASEPPASDVVVGTSSGALQLFIDAGVP
VNSDMISQFVHEALAETIAVMLGDREAKKQGPVAKSVSGNTSTNETNL-PVRVCTPVATP
QPTPPCSPP-----PPQEHVLVNTPDSSPCDSDQDVASSIKEICTEK----GSDIPAITL
VSTPTVTPVNTPPPAE--VLTP-TLSEISIDKLKLSSPDLPKPWDSGDLPLDEENPNS-L
QE----L-LHPRAIV-MSVAKDEEPGS-VDFPALPAAPE-PAPPTPLPEGTKPPSPQQNP
SSSSSTQENSLS-ITVTETETLDRHISEGEILLSCGQNLASK--VLGNG--DLYLMNVND
SLSSTLHDALEMEDDPPSEGQVI-RRPHKKLHANMILSLFTKQEQELLISQQA------E
DLDNSVGELSEGQRLVLTA-A-EDILAGPS-ICVPQP-TTSAEPSDQQADPGVLLQLSDM
A-SGDICEDSRASHGPMSLRELELQPCPNLVFPITHMA-TKGNGANLPGAAE--------
--------------------GFSQYQQK--HEPDIKQVEHK---PVQSHLTCVRNKSDSS
LSQQ--------------------------QGKLFL------------------------
------------------------------------------------------------
---------------

----------------------------MKSSEFS--------PGKKKRVKMPARRLREV
LSPNQEDNLALWKDEL------PR-VSPVLS-ASKRPPVRMGTN-MNGTLHGSSDITSSR
KYHKPPL-E----NSPPKS---LGLQELVQ----------------HSL-----------
-----------------------------------------------------LNIFYSF

PF15324 // ENSGT00390000012397_0_Domain_2 (241, 1068)

FIDRARS------MPIFKEVKVHLLEDAGREENTV-TQEARTSPSAIDSATTVAAATAAA
IATAAPLIKVQSDLEAKVNSVTELLNKLQETDKHLQRVTEQQASIQNK-EEKLHCH----
-NHEKRMNVFMEQQIKHLEKLQQQQMDIQTHFISAALKTNSF---QPGSMLPSRAVEKYS
VKP-EHPHLGSSNMSSHHTYTSKQ-------------------------EFEDMDFNEQK
SPLETPAPRRFAPVPVSRDDEMS----KKENPIEEKENMEMLGQ------RGNVRLLEQI
LNNNDSLIKKNEL-LDITSLTRPTMEWKLEKKNSIGTLPSQ-RFPSYE----DLGTSKVT
MQKSNDVLHDHGQKKKETNDMLQQKDLPIMM-----------------------------
----------------------RLA---DLPQNSV-KLQTANTTRSVLKDAAKILRGVQN
NKKVLEENLEAIIRAKDGAAMYSFINALSTNREISEKIRIKKIVDEWIKTISAEIQDELA
RKDYEKKR---SDLKNQ--RTKKAQ-N----MSKDTKTNTKDKT----VNRPIIPRQHSQ
KQIEEHFRSPPMR-RSMPASAVQK-ERKEGHLKSTTVIQDDDYM-LQIYGKPVYQGHRST
LKKGPYLRFNSPSPKS-KPQRPKVIERVKGTKVKSIRTQTDFYATKSMKVDSKIQHPVTT
-PPHGD-QQYLFSPSREMPTLSGTLEGHLIPMAILLGQTQSNSDSMRPIGVMANKPHPIT
VTTSIPP---SFRKSETGIKKPNIAVVEMKSEKKDPPQLSVQLLPSAEQLEA--------
-------------V-LPPAHS-------------------------LAQPPEE-EKCDEI
PESSEPLLEFNRSVQVASTKYNGPPFPPVISTFQP--TTEILDKVIERKETLE--NSLIQ
WVEQEIMSRIISELHPIQQ-QARLNASVS-VSEASEPMTSDIVEGTSYGALQLFVDAGVP
VNSDMISHFVNEALAETIAVLLGDRETKKQDPVATSVSGDVLSKETYF-PARVCTPVATP
QPTPPRSPSS----PPKDRVLVKTPDSSPCDSDHDGAFSVKDVFPEK----GHDMPTMTL
VNTPAITPAPSPPPAAAAALTP-TLSEISIDKLKISSPELPKPWGDGDLPLDEENPNS-L
LE----GFVHPRAIV-MSVAKDEEPES-VDFPAQPAPPE-PVPLTPFPAATKAPSPLQMP
SSGSSTMESTLS-ITVTETETLDRPISEGEVLFSCGQKLAPK----RAG--EIYLTHLND
SLSSTLQDALEMEDDPPSEGQVI-GMPHKKLHADAILSLLTKQNQELLVSQQS-------
DLEHSVGELSEGQRPKLTA-AAEKILKGQS-LFMQQP-VANAESVDQPCDPKPFFQQFDT
V-SGGIYEDSCASRGPMSLGELELQPNTNLVLPTTLLT-TQKNDVNLQEAAE--------
--------------------DFSQYQQK--QDEDVKEVEHK---PVKSRLIHVRSKSDIT
LSP-Q--------------------------DGEAMPLFTPQMSP--------AKMSVTL
PSMKPEDCSQSLSV--------------------------STIQGDVESSGEDTF-----
---------------

----------------------------MKGSEFS--------PGKETRVKMPTRRLREV
VSPNQGDNWPFIKDEL------PY-VPPALP-ANRRLPVGMRTS-RNGTSCGSSVLTSAK
KHHQPQL-D----NHAA-SK--SEFSKDIIVSR--LPLDKTEENNKQKGKRI--QK----
----------VWCVA---------------------------------------------
----

PF15324 // ENSGT00390000012397_0_Domain_2 (245, 1648)

-QN------MPVFKEVKVHLLENTSTDKDAV-VQEARTSPSGIDSATTVAAATAAA
IATAAPLIKVQSDLEAKVNSVTELLNKLQETDKQLQRVTE-QTDIQNK-QDKLHCH----
-DHEKQMNVFMEQHIRHLEKLQQQQLDIQSHFIRSALKTSSF---QPVCIPSSRAVEKCS
INP-GHPHLGSSSLSFRNTFASR----------------------------QDTGFDEQM
SPLETPAPRKFAPVPVSRDDEIS----KRENPLEEKENMDTSSP------RGNVRLLEQI
LNSNDALTRKSDS-SDITSLAKSKMGWNSEKKKLTKKIFIYYLFD--R----ERGSERVG
VP---------GPLVTANELQMRSKPSPITL-----------------------------
----------------------RAS---DLSQNSV-KLQST-NTRSVLKDAEKILRGVQN
NKKVLEENLEAIIRAKDGAAMYSFVNVLASSREMSEKIRIKQKVDEWIKTISAEIQDELA
RKDYEQKR---FDPRNQ--RTKRAQ-N----MSRDIKANIQDKT----VNTSVIPRNLSQ
KQIQECFRSPPGR--SMPASGLQK-ERREGRLKSTTILQDEDYM-LQIYGKPVYQGHRST
LKKGPYLRFNSPSPKV-KPQRPKLIEQIKGTKVKSARTQTDFYAAKPMKVDPKVHHSITT
-LPPGD-QQYLFSPSREMPTSSGTLEGHLIPMAILLGQTQSNSDSMPPAGVIVNKPHPVT
VTTSIPPIPQSSRKIETGVKKPNVAVVEMKSEKKDPPQLTVQVCQIARIKGV--------
-----------------RHHTWLQTPDFVQVDEAEVKLPGTDFDEVIDVIQEE-EKCDEI
PEYSEPMLEFNRSVKVVSTKYNGPPFPPAVSNLQP--TTDILDKVIERKETLE--NNLLQ
WVEQEIMSRIISGLFPLQQ-QARLNASVS-VSEATESSTSDIVEGASGGALQLFVDAGVP
VNSDMIHHFVNEALAETIAVMLGDREAKKEGPVRTDVSGDVSTNEASL-LARVCTPVATP
QPTPPCSPS-----PPKEHVFVKTPDSSPCDSDHDVAFPVKEVPAVK----GADIPAITL
VNTPTVTPITSPPPAA--ALTP-TLSEISTDKLKMSSPELPKPWGDGDLPLDEENPNS-L
QE----E-LPHPKAIIMSVAKDEEPES-MDFPVLPVPLE-PVPLMPIPLVTKALSPPHVP
SSGSSTLESTPS-VTVTETETVDRPISEGEILFSCGQNLASK-----RN--GLCLANLND
SLSSTLHDALEMDDDPLSEGQVV-RMPHKQLHSDAILSLLMKRDQELVASQQV------Q
DLDDSVGEVSEGQRPRLTV-ATENILTGPS-LCVPQP-AAVAECLDQQSVPRLLVQQSDI
A-PGNIHEDSYASHGPMSLGELELQPNSNLILPTTLLTAAKENDNNLSEAAE--------
--------------------DFSQYEQK--QDLDVKQLEQSSTMPAHSRLILVRSKSDIS
LSQQ--------------------------QGGETIPLFTSQASP--------TKLSVML
PSVNLEDCSQSQSV--------------------------STVQGDMESSGTDTF-----
---------------

------M--------FW-CGTCFVN-NNMKGSEVS--------LEKKKRIKMPAKRLREV
VSQNHGDHLVLLKDEL------PC-VPPALS-ANKRLPVGTGTS-LNGTSCGSSDLTSAR
NCHQPLK-E----NPMVSE---SDFSKDIAVQV--LPLDKIEENNKQKANDI--FISQYT
VGQKDALRTVLKQKQCLTLSHMLECSGVITTDCTLYH---------LRLMRSSHLSLLSN
WDY

PF15324 // ENSGT00390000012397_0_Domain_2 (244, 1649)

RSQSM------PVVKEVKVHLLEDAGIEKDAV-TQETRISPSGIDSATTVAAATAAA
IATAAPLIKVQSDLEAKVNSVTELLSKLQETDKHLQRVTEQQTSIQSK-QEKLHCH----
-DHEKQMNVFMEQHIRHLEKLQQQQIDIQTHFISAALKTSSF---QPVSMPSSRAVEKYS
VKP-EHPNLGSCNASLYNTFASKQA---------------------SLKEVEDTSFDKQK
SPLETPAPRRFAPVPVSRDDELS----KRENLLEEKENMEVSCH------RGNVRLLEQI
LNNNDSLTRKSES-SNTTSLTRSKIGWTPEKTN---------RFPSCE----ELGTTKVT
LQKSDDVLHDLGQKEKETNSMVQPKESLSML-----------------------------
----------------------KLP---DLPQNSV-KLHTTNTTRSILKDAEKILRGVQN
NKKVLEENLEAIIRAKDGAAMYSLINALSTNREMSEKIRIRKTVDEWIKTISAEIQDELS
RTDYEQKR---FDQKNQ--RTKKGQ-N----MTKDIRTNTQDKT----VNKSVIPRKHSQ
KQIEEHFRNLPTR--GMPTSSLQK-ERKEGLLRATTVIQDEDYM-LQVYGKPVYQGHRST
LKKGPYLRFNSPSPKS-KPQRPKVIERVKGTKVKSIRTQTDSYATKPMKIDSKMKHSVPM
-LPHGD-QQYLFSPSREMPTFSGTLEGHLIPMAILLGQTQSNSDTMPPAGVIVSKPHPVT
VTTSIPP---SSRKVETGVKKPNIAVVEMKSEKKDPPQLTVQVLPSVDIDSISNGSTDVG
SPL-SSP---KEAS-LPPVQAWIKTPEIMKVDEEEVKFPGTNFDEIIDVIQEE-EKCDEI
PD-SEPILEFNRSVKADSTKYNGPPFPPVASTFQP--TANILDKVIERKETLE--NSLIQ
WVEQEIMSRIISGLFPIQQ-QIAPNISVS-VSETSDPLTSDLVEGTSSGALQLFVDAGVP
VNSDMINHFVNEALAETIEVMLGDREAKKQGPVATGVSGDASTNETYL-PARVCTPLATP
QPTPPCSPSS----PTKECVLVKTPDSSPCDSDHDMAFPVKEIYAEK----GDDMPAIML
VKTPTVTPTTTPPPAV-AVFTP-TLSDISVDKLKVSSPELPKPWE--------ENPNS-P
Q-----EELHPRAIV-MSVAKDEEPES-MDFPAQPPPPE-RVSFMPFPAGTKAPSPSQMP
GSDSSTLESTLS-VTVTETETLDKPVSEGEILFSCGQKLAPK--ILEDV--GLYLTNLND
SLSSTLHDAVEMEDDPPSEGQVI-RISHKKFHADAILSVLAKQNQESAVSQQAVCHS--E
DLENSVGELSEGQRPQLTA-AAENILMGHS-LYTQPP-VTNAQSLDQQCDPKPLSRHFDA
V-SGSIYEDSCASHGPVSLGELELEPNSNLVLPTTLLT-LQENDVNLPVAAE--------
--------------------DFSQYQQK--RNQDVKQVEHK---PSQS-YLHVANKSDIA
PSQ-QQVSP--GDMDQTQNELN-PYLTCVFTGKSFTLKKV----SCIGKLGPREFVIQII
PS-----PRWESNATLRFTDAPCQGVHDAALSEPRGLLSVSEH--QHDAGGRGVFGGRYL
LNGKRQPAQCLCH--

----------------------------MKGSEVS--------PEKKKRVKIPAKRLREV
VSPNHGDNLALLKDEL------PC-VPPALP-ANKRLPVRTRTS-LNGTSCD--------
----------------------------IAVQG--LPLDKTEESNTQKGKRIELIF

PF15324 // ENSGT00390000012397_0_Domain_1 (177, 870)

FIYT
MGQKDAVRTVLKQKA---------------------------------------------
-----QS------MPVVKEVKVHLLEDTGTEKDAV-TQETRTSPGGIDSATTVAAATAAA
IATAAPLIKVQSDLEAKVNSVTELLNKLQETDKHLQRVTEQQTSIQNK-HEKLHCH----
-DHEKQMNVFMEQHIRHLEKLQQQQIDIQVSIIHLELLTSSD---PPTSASQSARITGVS
HCTWPKVLKLHCNYCLYQWFLAWES---------------------PLREVEDTGFDKQK
SPLETPAPRRFAPVPVSWGGELS----KRENPMEEKENMEMSGH------RGNKAIIISS
LSS------------GNLSQISSVLEWHTE------TLPSQ-RFPSHE----ELETAKVT
MQKSDDVLHDLGQQKKETNGMVQPKESLIML-----------------------------
----------------------KLA---YFPQNYV-KLQTTHMTRSVLKDAEKILRRVQN
NKKVLEENLEAIIRAKDGAAMYSFINALSTSREMSEKIRIRKTVDEWIKTISAEIQ----
------------------------------------------------------------
-----------------------------GLLKATTAIQDEDYM-LQVYGKPVYQGHRST
LKKGPYLRFNSPSPKS-KPLRPKVIEQVKGTKVKSIRTQTDFYAAKPVKVDSKMKHSITT
-LPHGD-QQYLFSPSREMPTFSGTLEGHLIPMAILLGQTQSNSDSMPPAGIIVNKPHPIT
VTTSIPP---SSRKIESGVKKPNIAVVEMKSEKKDPPQLTVQVLPSVDIDSISNASADVD
PPL-PSP---KAAS-LPPLQTWIQTPEIMKIHEEEVKFPGTNFDEVIDVIQEE-EKCDEI
PD-SEPIMEFNRGVKVVSTKYNGPPFPPVASTFEP--TADILDKVIERKETLE--NSLIQ
WVEQEIMSRIISGFFPVQQ-QAIPNVSVS-VSEASEPLNSDIVEGTSSGVFQLFVDAGVP
VNSDMISHFVNEALAETIAVMLGDREAKKQGPVATSVAGDVSANETYL-PARVCTPVATP
QPTPPHSPSS----PPKERVLVKTPDSSPCDSDHDVAFPTKEIFAEK----GNDTPAITL
IATPAVTPAATPPPA--AALTP-TLSEISIDKLKVSSPELPKPWGDGDLPLEEENPNLTL
QE----ELLHPTAIV-MSVAKDEEPSSVLDFPAQPAPPE-PVPFMPFPAGNKAPSPPQMP
NYDSSTLESTLS-VTVTETETLDRPISEGEILFSCGQKLAPK--SKLICINCFHWLDYDN
SLS---NTFLFKEDDSPSEGQVI-RMPHKKSHADAILSLLAKQNQESLILQQAVYHS--E
HITFIVQSN---------------LSANDN-LY---------------LQPLPVPHH---
---YGIDEDSCVSHGPMSLGELELQPNSNFVLPTTLLK-TQENDVNLPVAAE--------
--------------------DFSQ------------------------------------
--------------------PN-LYLASVFTGGKAVPLLTSQTVP--------AKMSVTL
PSVNLEDLSQSQSI--------------------------STIQGDMESSGTDTF-----
---------------

------M--------FW-CGTCFVT-NNMKGSEVS--------LEKKKKIKMPVKRLREV
VSQNHGDHLVLLKDEL------PC-VPPALS-ANKRLPVGTGTS-LNGTSRGSSDLTSAR
NCYQPLL-E----NPMVSE---SDFSKDVAVQV--LPLDKIEENNKQKANDI--FISQYT
MGQKDALRTVLKQNVSLCLTGWS--SGVITTHCSLYL---------LRLMRSSHLSLPSS
WDY

PF15324 // ENSGT00390000012397_0_Domain_2 (244, 1649)

RAQSM------PVFKEVKVHLLEDAGIEKDAV-TQETRISPSGIDSATTVAAATAAA
IATAAPLIKVQSDLEAKVNSVTELLSKLQETDKHLQRVTEQQTSIQRK-QEKLHCH----
-DHEKQMNVFMEQHIKHLEKLQQQQIDIQTHFISAALKTSSF---QPVSMSSSRAVEKYS
VKP-EHPNLGSCNPSLYNTFASKQA---------------------PLKEVEDTSFDKQK
SPLETPAPRRFAPVPVSRDDELS----KRENLLEEKENMEVSCH------RGNVRLLEQI
LNNNDSLTRKSES-SNTTSLTRSKIGWTPEKTN---------RFPSCE----ELETTKVT
MQKSDDVLHDLGQKEKETNSMVQPKESLSML-----------------------------
----------------------KLP---DLPQNSV-KLQTTNTTRSVLKDAEKILRGVQN
NKKVLEENLEAIIRAKDGAAMYSLINALSTNREMSEKIRIRKTVDEWIKTISAEIQDELS
RTDYEQKR---FDQKNQ--RTKKGQ-N----MTKDIRTNTQDKT----VNKSVIPRKHSQ
KQIEEHFRNLPMR--GMPASSLQK-ERKEGLLKATTVIQDEDYM-LQVYGKPVYQGHRST
LKKGPYLRFNSPSPKS-RPQRPKVIERVKGTKVKSIRTQTDFYATKPMKMDSKMKHSVPV
-LPHGD-QQYLFSPSREMPTFSGTLEGHLIPMAILLGQTQSNSDTMPPAGVIVSKPHPVT
VTTSIPP---SSRKVETGVKKPNIAIVEMKSEKKDPPQLTVQVLPSVDIDSISNSSADVL
SPL-SSP---KEAS-LPPVQTWIKTPEIMKVDEEEVKFPGTNFDEIIDVIQEE-EKCDEI
PD-SEPILEFNRSVKADSTKYNGPPFPPVASTFQP--TADILDKVIERKETLE--NSLIQ
WVEQEIMSRIISGLFPVQQ-QIAPNISVS-VSETSEPLTSDFVEGTSSGALQLFVDAGVP
VNSNVIKHFVNEALAETIAVMLGDREAKKQGPVATGVSGDASTNETYL-PARLCTPLATP
QPTPPRSPSS----PTKECVLVKTPDSSPCDSDHDMAFPVTEICAEK----GDDMPAIML
VNTPTVTPTTTPPPAA-AVFTP-TLSDISIDKLKVSSPELPKPWRDGDLPLEEENPNS-P
Q-----EELHPRAIV-MSVAKDEEPES-MDFPAQPPPPE-PVPFMPFPAGTKAPSPSQMP
GSDSSTLESTLS-VTVTETETLDKPISEGEILFSCGQKLAPK--ILEDI--GLYLTNLND
SLSSTLHDAVEMEDDPPSEGQVI-RMSHKKFHADAILS-FAKQNQESAVSQQAVCHS--E
DLENSVGELSEGQRPQLTA-AAENILMGHS-VYMQPP-VTNTQSLDQQCDPKPLSRQFDT
V-SGSIYEDSCASHGPMSLGELELEPNSKLVLPTTLLT-AQENDVNLPVAAE--------
--------------------DFSQYQLK--QNQDVKQVEHK---PSQS-YLRVRNKSDIA
PSQ-QQVSP--GDMDRTQIELN-PYLTCVFSGLGVHVKKV----SCIGKLRLWRFVIQII
SS-----PRWESSATLRFTDAPCQDVSDAAVSELRGLLSVSES--QHNAGGHGVFGGRYL
LNGKRQPAQCLCHWF

------------------------------------------------------------
------------------------------------------------------------
---------------MVSE---SDFSKDVAVQV--LPLDKIEENNKQKA

PF15324 // ENSGT00390000012397_0_Domain_2 (170, 1649)

NDI--FISRYT
MGQKDALRTVLKQ-----------------------------------------------
---KAQNM------PVFKEVKVHLLEDAGIEKDAV-TQETRISPSGIDSATTVAAATAAA
IATAAPLIKVQSDLEAKVNSVTELLSKLQETDKHLQRVTEQQTSIQRK-QEKLHCH----
-DHEKQMNVFMEQHIKHLEKLQQQQIDIQTHFISAALKTSSF---QPVSMSSSRAVEKYS
VKP-EHPNLGSCNPSLYNTFASKQA---------------------PLKEVEDTSFDKQK
SPLETPAPRRFAPVPVSRDDELS----KRENLLEEKENMEVSCH------RGNVRLLEQI
LNNNDSLTRKSES-SNTTSLTRSKIGWTPEKTN---------RFPSCE----ELETTKVT
MQKSDDVLHDLGQKEKETNSMVQPKESLSML-----------------------------
----------------------KLP---DLPQNSV-KLQTTNTRRSVLKDAEKILRGVQN
NKKVLEENLEAIIRAKDGAAMYSLINALSTNREMSEKIRIRKTVDEWIKTISAEIQDELS
RTDYEQKR---FDQKNQ--RTKKGQ-N----MTKDIRTNTQDKT----VNKSVIPRKHSQ
KQIEEHFRNLPMR--GMPASSLQK-ERKEGLLKATTVIQDEDYM-LQVYGKPVYQGHRST
LKKGPYLRFNSPSPKS-RPQRPKVIERVKGTKVKSIRTQTDFYATKPMKMDSKMKHSVPV
-LPHGD-QQYLFSPSREMPTFSGTLEGHLIPMAILLGQTQSNSDTMPPAGVIVSKPHPVT
VTTSIPP---SSRKVETGVKKPNIAIVEMKSEKKDPPQLTVQVLPSVDIDSISNSSADVL
SPL-SSP---KEAS-LPLVQTWIKTPEIMKVDEEEVKFPGTNFDEIIDVIQEE-EKCDEI
PD-SEPILEFNRSVKADSTKYNGPPFPPVASTFQP--TADILDKVIERKETLE--NSLIQ
WVEQEIMSRIISGLFPVQQ-QIAPNISVS-VSETSEPLTSDFVEGTSSGALQLFVDAGVP
VNSNVIKHFVNEALAETIAVMLGDREAKKQGPVATGVSGDASTNETYL-PARVCTPLATP
QPTPPRSPSS----PTKECVLVKTPDSSPCDSDHDMAFPVKEICAEK----GDDMPAIML
VNTPTVTPTTTPPPAA-AVFTP-PLSDISIDKLKVSSPELPKPWRDGDLPLEEENPNS-P
Q-----EELHPRAIV-MSVAKDEEPES-MDFPAQPPPPE-PVPFMPFPAGTKAPSPSQMP
GSDSSTLESTLS-VTVTETETLDKPISEGEILFSCGQKLAPK--ILEDI--GLYLTNLND
SLSSTLHDAVEMEDDPPSEGQVI-RMSHKKFHADAILS-FAKQNQESAVSQQAVCHS--E
DLENSVGELSEGQRPQLTA-AAENILMGHS-VYMQPP-VTNTQSLDQQCDPKPLSRQFDT
V-SGSIYEDSCASHGPMSLGELELEPNSKLVLPTTLLT-AQENDVNLPVAAE--------
--------------------DFSQYQLK--QNQDVKQVEHK---PSQS-YLCVRNKSDIA
PSQ-QQVSP--GDMDRTQIELN-PYLTCVFSGGKAVPLSA----SQM---PPAKMSVMLP
SV-----NL-----------EDCSQ--------SLSLSTMQE---DMESSGADTF-----
---------------

----------------------------MKGSEVS--------PEKKKRLKMPARRLQEV
VSPNQGNNLAFLNSEL------PC-IPPALP-ANKRLPVRMGTP-VNGTLPGSSDLPSAR
-NYQPLL-E----NPTASE---SDFSKDVTMQE--LPLDKAEDSSRKEA

PF15324 // ENSGT00390000012397_0_Domain_2 (170, 1649)

DDI--FISQYT
VGQKDALRMALKQKA---------------------------------------------
-----QS------MPVFKEVKVHLLEDAGTEKGAV-LQEARVSPSGIDSATSVAAATAAA
IATAAPLIKVQSDLEAKVNSVTELLNKLQETDKHLKRVAEQQTSIQNK-QEKLHCH----
-DHEKQMNVFMEQHIRHLEKLQQQQIDIQTHFISAALKTSTC---PPASMLPSRAVEKHS
IKP-EHLHLGNSVLSSHNTIASKQA---------------------TLRKIEDMEFDELK
SPLETPAPRRFAPVPVSRDGKIS----KRENLIEEKENMEKSDH------GGNVRLLEQI
LNNNDFSTRKSES-SNITSLSRSKIGWNPERKDSFETLSSR-RFPSSE----ELRMAKVT
MQNPNDVLHDLGKKEKETNGTLQ-------------------------------------
--------------------------------NSG-KLQPTNTVRSVLKDAEKILRGVQN
NKKVLEENLEAIIRAKDGAAMYSFINALSTNREMSEKIRIRKTVDEWIKAISTEIQDEMA
RKDYEQRR---FDQKNQ--RTKKAQ-N----ISKDIKANTQDKT----VNKSVIPRK-PQ
KQVEDYLRRLPIR--NMATSSVQK-ERK-GLLKSPTVIQDEDYM-SQVYGKPVYQGHRST
LKRGPYLRFNSTSLNS-KPQRPKIIEQVKGTKVKSIRTQTDFHGIKPMKIDSRMQYPVTA
-LPRGE-QQYLFSPSREMPTFSGTLEGHLIPMAILLGQTQSNSDSVLPAGVIVHKPHPVT
VTTSIPP---SSGKVETGVKKPNVAVVEMKSEQKDPPRLTVQVLPRVDIDSISNDSADGG
SP-LPSP---RGAR-RSPPRMCTQTPEFMNVDEEEVKFPGTNFDEVIDVVQEE-EKCDEI
PECSEPILEFNRSIKVASTKYNGPPFPPVVCTSQP--TTDILDKVIERKETLE--NNLIQ
WVEQEIMSRIISGRFPVPQ-QTRLTTSVS-VSEASEPSTPDLVEGTCGGALQLFVDAGVP
VNSDTIRHLVNEALAETIAGMLGDRESKKQGHGATSVSGDISTSETPL-LARICTPVATP
QPTPPHSPAS----PPKEYVLVKTPDSSPCGSYHDVAFPVKEISAEKEKSSENDVPAITL
INTPTVTPATTPPLA--AALTP-TLSEISIDKLKISSPELPTPWGDRDLPLDEENPYC-L
QE----D-FHPRAIV-MSVAEDEEPES-MNFLPPPAPTE-PVPPTPFPAGTKAPSSSQMP
SSSSSTLESTLS-VTVTDMESLDRPISEGEIVFNCGERLAPR--ILGGG--ELYLTNLND
SLSSTLHDALDMEDDSPSEGQVI-RIPHKKFHADSILPLLARQNQELLVSQQAVCCS--E
DLENSVGELSEGQRPRLTA-AAENILLGQS-LYMQQC-VANAESMGQQCHPKPLFQQFDT
V-SGGIHEDPCASHGPMSLGELELQPRSNVVLPTALLR-TQGSDVYLPEAAE--------
--------------------DFSQNQQK--QDQDVKQVEHK---PVQSHLIRVRNISDIL
LSQQQQGKT--FFITNNNITGFFFCFGFWYWGLNSGPCTCEAGGS--------TTELNPW
PSII--------------------------------------------------------
---------------

------M--------FW-CGTCFVT-NNMKGSEVS--------LEKKKRIKMPAKRLREV
VSQNHGDHLVLLKDEL------PC-VPPALS-ANKRLPVGTGTS-LNGTSPGSSDLTSAR
NCHQPLL-E----NPMVSE---SDFSKDVAVQV--LPLDKIEENNKQKANDV--FISQYT
MGQKDALRTVLKDGVSR-HPGWSAVARSRLIAT--SA---------SQVQAVSCLSLPSS
WDY

PF15324 // ENSGT00390000012397_0_Domain_2 (244, 1649)

RAQSM------PVFKEVKVHLLEDAGIEKDAV-TQETRISPSGINSATTVAAATAAA
IATAAPLIKVQSDLEAKVNSVTELLSKLQETDKHLQRVTEQQTSIQRK-QEKLHCH----
-DHEKQMNVFMEQHIRHLEKLQQQQIDMQTHFISAALKTSSF---QPVSMPSSRAVEKYS
VKP-EHPNLGSCNPSLYNTFASKQA---------------------PLKEVEDTSFDKQK
SPLETPAPRRFAPVPVSRDDELS----KRENLLEEKENMEVSCH------RGNVRLLEQI
LNNNDSLTRKSES-SNTTSLTRSKIGWTPEKTN---------RFPSCE----ELGTTKVT
MQKSDDVLHDLGQKEKETNSMVQPKESLSML-----------------------------
----------------------KLP---DLPQNFA-KLQTTNTTRSVLKDAEKVLRGVQN
NKKVLEENLEAIIRAKDGAAMYSLINALSTNREISEKIRIRKTVDEWIKTISAEIQDELS
RTDDEQKR---FDQNNQ--RTKKGQ-N----MTKDIRTNTQDKT----GNKSVIPRKHSE
KRMEEHFRSLPMR--GMPASGLQK-ERKEGLLKATTVIQDEDYM-LQVYGKPVYQGHRST
LKKGPYLRFNSPSPKS-RPQRPKVIERVKGTKVKSIRTQTDFYATKPMKMDSKMKHSIPV
-LPHGD-QQYLFSPSREMPTFSGTLEGHLIPMAVLLGQTQSNNDTMPPAGVIVSKPHPVI
VTTSIPP---SSRKVETGVKKPNIAIVEMKSEKKDPPQLTVQVLPSVDIDSISNGSADGL
SPL-SSP---KEAS-LPPVQTWIKTPEIMKVDEEEVKFPGTNFDEIIDVIQEE-EKCDEI
PD-SEPILEFNRSVKADSTKYNGPPFPPVASTLQP--TADILDKVIERKETLE--NSLIQ
WVEQEIMSRIISGLFPVQQ-QIAPNISVS-VSETSEPLTSDIVEGTSSGALQLFVDAGIP
VNSDVINHFVNEALAETIAVMLGDREAKKQGPVATGVSGDASTNETCL-PARVCTPLATP
QPTPPRSPSS----PTKECVLVKTPDSSPCDSDHDMAFPVKEIRAEE----GDDMPAIVL
VNTPTVTPTTTPPPAA-AVFTP-TLSDISVDKLKVSSPELPKPWGDGDLPLEEENPNS-P
Q-----EELHPRAIV-MSVAKDEEPES-MDFPAQPPPPE-PVPFMPFPAGTKAPSHSQMP
GSDSSTLESTLS-VTVTETETLDKPISEGEILFSCGQKLAPK----KDV--GLYLTNLND
SLSSTLHDAVEMEDDPPSEGQMI-RMSHKKFHADAILS-LAKQNQESAVSQQAVCHS--E
DLENSVGELSEGQRPQLTA-AAENILMGHS-LYMQPP-VTNAQSLDQQCDPKPLSRQFDT
V-SDNIYEDSCAR------GELELESNSNLVLPTTLLT-AQENDVNLPVAAE--------
--------------------DFSQYQQK--QNQDVKQVEHK---SSPS-YLRVRNKSDIA
SSQ-QQVSP--GDMDWTQIELN-PYLTCVFSGLGVHVKKV----SCIGKLGPWGFVIQII
SS-----PRWESSATLRFTDAPCQDVGDAALSEPRGLLSVCES--QHNAGGHGVFGGRYL
LNRKRQPAQCLCHWF

------------------CGTCFVN-NNMKGSEVS--------LEKKKRIKMPAKRLREV
VSQNHGDHLVLLKDEL------PC-VPPALS-ANKRLPVGTGTS-LNGPSCGSSDLTSAR
NCHQPLK-E----NPMVSE---SDFSKDVAVQV--LPLDKIEENNKQKANDI--FISQYT
VGQKDALRTVLKIPIFFYLFIYLEMESHIAQAGVQWHDLGSLQPPPPSFKGFSCLSLPSS
WDY

PF15324 // ENSGT00390000012397_0_Domain_2 (244, 1649)

RAQSM------PVVKEVKVHLLEDAGIEKDAV-TQETRISPSGIDSATTVAAATAAA
IATAAPLIKVQSDLEAKVNSVTELLSKLQETDKHLQRVTEQQTSIQSK-QEKLHCH----
-DHEKQMNVFMEQHIRHLEKLQQQQIDIQTHFISAALKTSSF---QPVSMPSSRAVEKYS
VKP-EHPNLGSCNASLYNTFASKQA---------------------SLKEVEDMSFDKQK
SPLETPAPRRFAPVPVSRDDELS----KRENLLEEKENMEVSCH------RGNVKLLEQI
LNNNDSLTRKSES-SNTTSLTRSKIGWTPEKTN---------RFPSCE----ELGTTKVT
LQKSDDVLHDVGQKEKETNSMVQPKESLSML-----------------------------
----------------------KLP---DLPQNSV-KLHTTNTTRSILKDAEKILRGVQN
NKKVLEENLEAIICAKDGAAMYSLINALSTNREMSEKIRIRKTVDEWIKTISAEIQDELS
RTDYEQKR---FDQKNQ--RTKKGQ-N----MTKDIRTNTQDKT----VNKSVIPRKHSQ
KQIEEHFRNLPTR--GMPTSSLQK-ERKEGLLKATTVIQDEDYM-LQVYGKPVYQGHRST
LKKGPYLRFNSPSPKS-KPQRPKVIERVKGTKVKSIRTQTDSYATKPVKIDSKMKHSVPM
-LPHGD-QQYLFSPSREMPTFSGTLEGHLIPMAILLGQTQSNSDTMPPAGVIISKPHPVT
VTTSIPP---SSRKVETGVKKPNIAVVEMKSEKKDPPQLTVQVLPSVDIDSISNGSTDVG
SPL-CSP---KEAS-LPPVQAWIKTPEIMKVDEEEVKFPGTNFDEIIDVIQEE-EKCDEI
PD-SEPILEFNRSVKADSTKYNGPPFPPVASTFQP--TANILDKVIERKETLE--NSLIQ
WVEQEIMSRIISGLFPIQQ-QIAPNISVS-VSETSDPLTSDLVEGTSSGALQLFVDAGVP
VNSDMINHFVNEALAETIEVMLGDREAKKQGPVATGVSGDASTNETYL-PARVCTPLATP
QPTPPCSPSS----PTKECVLVKTPDSSPCDSDHDMAFPVKEIYAEK----GDDMPAIML
VKTPTVTPTTTPPPAV-AVFTP-TLSDISVDKLKVSSPELPKPWGDGDLPLEEENPNS-P
Q-----EELHPRAIV-MSVAKDEEPES-MDFPAQPPPPE-PVSFMPFPADTKAPSPSQMP
GSDSSTLESTLS-VTVTETETLDKPISEGEILFSCGQKLAPK--ILEDV--GLYLTNLND
SLSSTLHDAVEMEDDPPSEGQVI-RMPHKKFHADAILSVLAKQNQESAVSQQAVCHS--E
DLENSVGELSEGQRPRLTA-AAENILMGHS-LYTQPP-VTNAQSLDQQCDPKPLSWHFDA
V-SGSIYEDSCASHGPMSLGELELEPNSNLVLPTTLLT-LQENDVNLPVAAE--------
--------------------DFSQYQQK--RNQDVKQVEHK---SSRS-YLHVTNKSDIA
PSQ-QQVSP--GDMDQTQNELN-PYLTCVFTGKSFTLKKV----SCIGKLGPQGFVIQII
PS-----PRWESNATLRFTDAPCQGVHDAALSEPRGLLSVSEH--QHDAGGRGVFGGRYL
LNRKGQPAQCLCH--

----------------------------MKGSEVS--------LKKQNRLKMPARRLREV
VSPNQGNNIALLKGEL------PC-VPPALP-ANKRLPVRMGTS-ISGTLPGSSDLPSAG
-NYQPLL-E----NPTASE---SDFSKDVAVKE--LPLDKTEDRSRREV

PF15324 // ENSGT00390000012397_0_Domain_2 (170, 1649)

DDI--FISQYS
VGQKDALRTILKQKA---------------------------------------------
-----QS------IPIFKEVKVHLLDDAGVEKVAA-PPEARGSPSGIDSATAVAAATAAA
IATAAPLIKVQSDLEAKVNSVTELLNKLQETDKHLKRVTEQQTSIQNK-QEKLYCH----
-DHEKQMNVFMEQHLKHLEKLQQQQIDIQTHFISAALKTNTF---PPASTLAPRAMEKHS
REP-GCPFVGGSMLSSHEPFASKQA---------------------TLRKVEDTYFDEQE
SPLETPAPRRFAPVPVSRDGEMP----KRENPMEEKENMEKSDY------KGNTRLLGQI
LNNNDSSTRKSES-SDITSLSRSKLGWNPERRHSFEALSSQ-RFPSSG----EPGTAIVT
VQKPNDVLQDLGQKRKETNSVLQ-------------------------------------
--------------------------------SSC-KLQTTNT-RSVLKDAEKILRAVQN
NKKMLEENLEAIIRAKDGAAMYSFINALSTNREITEKIRIRKTVDEWIKAISAEIQDELA
RKDFEQRR---FAQKNQ--RTQKAQ-I----MSKDIKANTQDKT----VNKSVILKK-PQ
KQVEDYFRSPPAR--SMAVSSLQK-ERKAGPLKSPTMIRDEDYM-SQVYGKAVYQGHRST
LKRGPYLRFNSTSLKS-KPQRPKVIEQVKGTKVKSIRTQTDLHATKPMKTDSKMQHSIPA
-LPHGE-QQYVFSPSREMPTFSGTLEGHLIPMAILLGQTQSNSDSLPPAGV-VHKLHPVT
VTTSIPP---SSRKVETGVKKPNIAVVEMKSEKKDPPQLTVQVLPSVDIDSVSNSSAPSS
LPFLSSP---EGAP-FPLMRMCTQSPEFMKANEEEVKFPGSNFDEVIDVIQDE-EKCDEI
PEYSEPILEFNRSVKVVSTKYNGPPFPPVLSTAQP--TTDILDKVIERKNTLE--NNLIQ
WVEQEIMSRIISGHFPVPS-QTKLPASIS-VSEASEPSTPDIVEGTCGGALQLFVDAGVP
VSSGTIRRLVNDALAETIAGMLGDRESKKESPVAAGVPGDVSTSETLL-LTRICTPVATP
RPTPPCSPSS----PPKECVLLKTPDSSPCGSYHDVTFPVKEISAEKERSVGQDIPAVTL
VNTPSVTPTATPPLA--AALTP-TLSETSIDKLKISSPELPKPWGDRDLPLDEENPNS-F
QE----ELLHPGALV-MSVAKDEEPRS-MDSPAPLTPAE-PPPLTQLPVCAEVPASLQVL
SSSSSTLESTLS-LTITGMETLDRPISEGEIVFSCGQRLAPG--ILEGG--ELYLTNLND
SFSSTLHDALEMEDDSPSEGQVI-RIPHKNFHTNEILPLLAKQNQELQGSQQAVYHS--E
DLENSVGELSEGQRPRLTA-AAKHVFLGQA-LCMQQR-ITSAESVSQQCTHKPLLQQFDA
V-SGGICEDSCASRGPMSLGELELQPDSSAGLSIAPLR-AQGSVVHLPEAAELKPLTSAS
PRGAALLRAGAHGQKPQVSCLRSLNQQK--QDQDVKQVEHM---PVQSRLMCVQNISDIS
LL----------------------------QGGETVPCFTSQPSP--------ARMCVTL
PAVNLEACSPSLSA--------------------------STIQGDAGSSGTDSF-----
---------------

----------------------------MKNVEFS--------LERGQRLKMPARKLREI
VSPNQGNKLVVVEDEL------PR-VPPALA-ANKRFAVETRTS-SNGTLCGSLDLTSAR
LYHQPLS-E----SPPASKK--SDFSKDAVVQR--LPLNKTEENNAPKA

PF15324 // ENSGT00390000012397_0_Domain_2 (170, 1646)

NDI--FISQYT
MGQKDALRTVLKQKA---------------------------------------------
-----QS------MPVFKAVKVHLLEDTSTEKNTV-AQETETPPNRIDSATTVAAATAAA
IATAAPLIKVQSDLEAKVNCVGELLTKLQETDKQLQRVTEHQASVQSK-QEKVHCH----
-DHEKQMNVFMEQHIRHLEKLQQQQIDIQTHFIDAALKASSL---Q-LGMSSSRAVEKYS
GKL-GSPSVGS-SVFSHNTFVSKRV---------------------PLS--EDTDFDGQK
SPLETPAPRRFAPVPVSRDGKIT----KRESPTEEKENMEMNSP------KGNVRLLEQV
LNSSECLTRKTEA-SDITSLTQPKMGWDLEKRDSTETLHSQ-IFPSSE----ERGTAQVP
VQKYSDVVPDLGQKK-QASDMLQIKQSPVTL-----------------------------
----------------------RLS---DHPHNPA-SLQTT-NTRSVLKDAAKILRGVQN
NKKVLEENLEAIVRAKDGAAMYSLINALATNREMSEKIRIRKQVDEWIKIISAEIQDELM
RKDYEQKR---FDPKNQ--RSKKAL-T----MSRDIKANNQDKT----VNRSVIPRSHYQ
KQTQEQFTSPPVR--NLPASGPQK-ER-SGLLKSTTTLQDEDYM-LQIYGKPVYQGHRST
LKKGPYLRFSSPSPKA-KPQRPRVIELVKGTKVKSARTQTDFHAASRMKMDSKIQHPITT
-LPHAD-QQYMFSPSREMPTVSGTLEGHLIPMAILLGQTQSNSDSIPPAGVTVNKTRPVT
VTTSIPP---ASRKGNTGVKKPNVAIVEMKSEKKDPPQLSVQVLPSVDIDSVSYSSTDGA
SSP-PSP---KEAS-LPPLHTWIQTPDFMKVDEEEVPLPGANFDEVIDVIQEE-EKRDEI
PECSAPMLEFNRSVKVVPSKYNGPSFPPVASAYHP--TTDILDKVIERKETLE--NSLIQ
WVEQEIMSRIISGLFPLQQ-QARLDASVS-VSEASEPSASDIVAGTSSGALQRMVDARVP
VNSDMVSHFVNEALTETIAVMLADREAERQRPAATSVPGDLSGAETNL-LARVCAPVATP
QPTPPCSPS-----PVREHVLVKTPDSSPCESDPDAASSIKEICVEK----GSDMPAVML
VSTPTRTPVTTPPPAA--ALTP-TLSEISIDKLKLSSPELPKPWDSGDLPLDEENPNS-L
QE----L-PHPRAVV-M-SVANEEPES-VDFSAHPAPPE-PAPSASLPEGTKAPSLQRVP
SSGSSTLENTLS--TVTETETLDRHISEGEILFSCGQNLATK----RPG--DLFLMNIND
SLSSTLQDALEMEDDPPSEGQVI-RRPYKKRHEDAIVALLTKQQRELLVSQHE------E
DLENSVGELSEGQRLVLKA-A-EDILAGPS-GRTMQP-TSPAEPSYQHAAPRLVLQQSDT
A-SGNICEDLCATHGPMSLRELELQPDSNLLLPITHTT-TKVSDVNLPEAAE--------
--------------------DFSQYQQK--QDSDIKQVEHK---PIQRHLTSVRNKSDSS
LSQH--------------------------RGGPADPLLIAHVSP--------ARMSVTL
PSANLEDCSQSLST--------------------------SSTHGGAESSGTDTF-----
---------------

----------------------------MKGSEVS--------LEKKKRIKMPAKRLREV
VSQNHGDHLVLLKDEL------PC-VPPALS-ANKRLPVGTGTS-LNGTSCGSSDLTSAR
NCHQPLK-E----NPMVSE---SDFSKDVAVQV--LPLDKIEENNKQKA

PF15324 // ENSGT00390000012397_0_Domain_2 (170, 1649)

NDI--FISQYT
VGQKDALRTVLKQ-----------------------------------------------
---KAQSM------PVVKEVKVHLLEDAGIEKDAV-TQETRISPSGIDSATTVAAATAAA
IATAAPLIKVQSDLEAKVNSVTELLSKLQETDKHLQRVTEQQTSIQSK-QEKLHCH----
-DHEKQMNVFMEQHIRHLEKLQQQQIDIQTHFISAALKTSSF---QPVGMPSSRAVEKYS
VKP-EHPNLGSCNASLYNTFASKQA---------------------SLKEVEDMSFDKQK
SPLETPAPRRFAPVPVSRDDELS----KRENLLEEKENMEVSCH------RGNVRLLEQI
LNNNDSLTRKSES-SNTTSLTRSKIGWTPEKTNSVETLPSQ-RFPSCE----ELGTTKVT
LQKSDDVLHDLGQKEKETNSVVQPKESLSML-----------------------------
----------------------KLP---DLPQNSV-KLHTTNTTRSILKDAEKILRGVQN
NKKVLEENLEAIIRAKDGAAMYSLINALSTNREMSEKIRIRKTVDEWIKTISAEIQDELS
RTDYEQKR---FDQKNQ--RTKKGQ-N----MTKDIRTNTQDKT----VNKSVIPRKHSQ
KQIEEHFRNLPTR--GMPTSSLQK-ERKEGLLKATTVIQDEDYM-LQVYGKPVYQGHRST
LKKGPYLRFNSPSPKS-KPQRPKVIERVKGTKVKSIRTQTDSYATKPMKIDSKMKHSVPM
-LPHGD-QQYLFSPSREMPTFSGTLEGHLIPMAILLGQTQSNSDTMPPAGVIISKPHPVT
VTTSIPP---SSRKVETGVKKPNIAVVEMKSEKKDPPQLTVQVLPSVDIDSISNGSTDVG
SPL-SSP---KEAS-LPPVQAWIKTPEIMKVDEEEVKFPGTNFDEIIDVVQEE-EKCDEI
PD-SEPILEFNRSVKADSTKYNGPPFPPVASTFQP--TANILDKVIERKETLE--NSLIQ
WVEQEIMSRIISGLFPIQQ-QIAPNISVS-VSETSNPLTSDIVEGTSSGTLQLFVDAGVP
VNSDVINHFVNEALAETIEVMLGDREAKKQGPVATGVSGDASTNETYL-PARVCTPLATP
QPTPPCSPSS----PTKECVLVKTPDSSPCDSDHDMTFPVKEIYAEK----GDDMPAIML
VKTPTVTPTTTPPPAV-AVFTP-TLSDISIDKLKVSSPELPKPWGDGDLPLEEENPNS-P
Q-----EELHPRAIV-MSVAKDEEPES-MDFPAQPPPPE-PVSFMPFPAGTKAPSPSQMP
GSDSSTLESTLS-VTVTETETLDKPVSEGEILFSCGQKLAPK--LLEDV--GLYLTNLND
SLSSTLHDAVEMEDDPPSEGQVI-RMPHKKFHADAILSVLAKQNQESAVSQQAVCHS--E
DLENSVGELSEGQRPQLTA-AAENILMGHS-LCMQPP-VTNVQPLDQQCDPKPLSRQFDA
V-SGSIYEDSCASHGPMSLGELELEPNSNLVLPTTLLT-LQENDVNLPVAAE--------
--------------------DFSQYQQK--RNQDVKQVEHK---PSQS-YLHVTNKSDIA
PSQ-QQVSP--GDMDQTQNELN-PYLTCVFTGGKAMPLSA----SQM---PPAKVSMTLP
SV-----NLE-----------DCSQS--------LSIS--------TMQEDVESSGADTF
---------------

------------------CGTSFVT-NNMKGSEVS--------LQKKKRVKMPAKRLREV
VSQNHGDRLVLLKDNL------PC-VPSALS-ANKRLPAGTGTR-VNGTSPGSSDLTSAG
NCHQSLL-E----YPMVSE---SNFSKDVGVQV--LPLDKIEENNKQKENDI--LISQYT
TGQKDALRTVLKQKLCLTLSHRLECSGAFTTHCSLYLLRL---------MRSSCLGLLSN
WDY

PF15324 // ENSGT00390000012397_0_Domain_2 (244, 1648)

KAQSM------PVFKEVKVHLLEDAGIEKDAV-TQETRISPSGIDSATTVAAATAAA
IATAAPLIKVQSDLEAKVNSVTELLSKLQETDKHLQRVTEQQTSIQSK-QEKLHCH----
-DHEKQMNVFMEQHIRNLEKLQQQQIDIQTHFISAALKTSSF---QPVSVPSSRAVEKYF
VKP-EHPNLGSCNPSSYNTFASRQA---------------------PLKEIEDMSFDKQK
SPLETPAPRRFAPIPVSRDDEPS----KRENLLEEKENMEVSCH------RGNVRLLEQI
LNNNDSLTRKSES-SNTTSLTRSKIGWNPEKTD---------RFPSYE----ELGTAKVT
VQKSDEVLHDLGQKKKETNGMVQPEESLSML-----------------------------
----------------------KLA---NLPQNSV-KLQTTSTTRSVLKDAEKILRGVQN
NKKVLEENLEAIIRAKDGAAMYSLINALSTNREMSEKIRIRRTVDEWIKTISAEIQDELS
RTDYEQKR---FDQKNQ--RTKKAH-N----MTKDIRTNTQDKT----VNKSVIPRKHSQ
KQIEERFRNLPMR--GMPAASIQR-ERKEGLLKASTVIQDEDYM-FQVYGKPVYQGHRST
LKKGPYLRFNSPSPKS-KPQRPKVIERVKGTKVKSIRTQTDFYATKPIKMESKTKHSIPV
-LPHGD-QQYLFSPSREMPTFSGTLEGHLIPMAILLGQTQSNSDSMPPAGVIVSKPHPVT
VTTSIPP---SSRKIETGVKKPNIAVVEMKSEKKDPPRLTVQVLPSVDIDSISNGSADVS
SPL-PSP---KEAS-LPPVQTWIKTPEIVKIDEEEVKFPGTNFDEVIDVIQEE-EKCDEI
PD-SEPILEFNRSIKADSTKYNGPPFPPVASTFQP--TADILDKVIERKETLE--NSLIQ
WVEQEIMSRMISGLFPIQQ-QIAPNISVS-VSETSEPLTSDIVEGTSNGALQLFVDAGVP
VNSDMIKHFVNEALAETIAVMLGDREPKKQDPVAASVSGDASTNETYL-PARVCTPLATP
QPTPPRSTSS----SPKECVLVKTPDSSPCDSDHDMAFPVKKVLAEK----GDDMPAVML
ANTPAVTPTTTPPPA--AVFTP-TLSEISIDKLKVSSPELLKPWGDGDLPLEEENPNS-P
Q-----EELHPRAIV-MSVAKDEEPES-MDFPAQPLPPE-PVPFMPFPAATKPPSPSQMP
GSDSSTLESTSS-VTVTETETSDKPISEGEILFSCGQKLAPK--ILEDV--GLYLTNLND
SLSSTLHDSVEMEDDPPSEGQVI-RMPHKKFHVDAILSLLAKQNQDSGVLQQAVYHS--E
DLENSMGELSEGQRPQLTAAAAENILMGYS-LYMQPP-VTNAESLDQQCDPKPSPQQFGT
V-SGGIYEDSCASHGPMSLGELELEPNSNHVLPTTLLT-ARENDVNLPVAAE--------
--------------------DFSQYPQK--RNQNVKQAEHK---PEQS-YLRIRNKCDIA
PLQ-QQ-----GDMDRTQTEPN-LYLTSVFTGKIFTLKNVS----CIGKLGPWGFVVQII
LSPTSPLCRWESSATLRFTDAPRRDVRAAALGEPRGLLSVSEH--QHDAGGHGVFRARYR
LNGKREPAHCLCHRF

------M--------FW-CGTCFVT-NNMKGSEVS--------LEKKKKIKMPVKRLREV
VSQNHGDHLVLLKDEL------PC-VPPALS-ANKRLPVGTGTS-LNGTSRGSSDLTSAR
NCYQPLL-E----NPMVSE---SDFSKDVAVQV--LPLDKIEENNKQKANDI--FISQYT
MGQKDALRTVLKQNVSLCLTGWSDHSGVITTHCSLYL---------LRLMRSSHLSLPSS
WDY

PF15324 // ENSGT00390000012397_0_Domain_2 (244, 1649)

RAQSM------PVFKEVKVHLLEDAGIEKDAV-TQETRISPSGIDSATTVAAATAAA
IATAAPLIKVQSDLEAKVNSVTELLSKLQETDKHLQRVTEQQTSIQRK-QEKLHCH----
-DHEKQMNVFMEQHIRHLEKLQQQQIDIQTHFISAALKTSSF---QPVSMPSSRAVEKYS
VKP-EHPNLGSCNPSLYNTFASKQA---------------------PLKEVEDTSFDKQK
SPLETPAPRRFAPVPVSRDDELS----KRENLLEEKENMEVSCH------RGNVRLLEQI
LNNNDSLTRKSES-SNTTSLTRSKIGWTPEKTN---------RFPSCE----ELETTKVT
MQKSDDVLHDLGQKEKETNSMVQPKESLSML-----------------------------
----------------------KLP---DLPQNSV-KLQTTNTTRSVLKDAEKILRGVQN
NKKVLEENLEAIIRAKDGAAMYSLINALSTNREMSEKIRIRKTVDEWIKTISAEIQDELS
RTDYEQKR---FDQKNQ--RTKKGQ-N----MTKDIRTNTQDKT----VNKSVIPRKHSQ
KQIEEHFRNLPMR--GMPASSLQK-ERKEGLLKATTVIQDEDYM-LQVYGKPVYQGHRST
LKKGPYLRFNSPSPKS-RPQRPKVIERVKGTKVKSIRTQTDFYATKPKKMDSKMKHSVPV
-LPHGD-QQYLFSPSREMPTFSGTLEGHLIPMAILLGQTQSNSDTMPPAGVIVSKPHPVT
VTTSIPP---SSRKVETGVKKPNIAIVEMKSEKKDPPQLTVQVLPSVDIDSISNSSADVL
SPL-SSP---KEAS-LPPVQTWIKTPEIMKVDEEEVKFPGTNFDEIIDVIQEE-EKCDEI
PD-SEPILEFNRSVKADSTKYNGPPFPPVASTFQP--TADILDKVIERKETLE--NSLIQ
WVEQEIMSRIISGLFPVQQ-QIAPSISVS-VSETSEPLTSDIVEGTSSGALQLFVDAGVP
VNSNVIKHFVNEALAETIAVMLGDREAKKQGPVATGVSGDASTNETYL-PARVCTPLPTP
QPTPPCSPSS----PAKECVLVKTPDSSPCDSDHDMAFPVKEICAEK----GDDMPAIML
VNTPTVTPTTTPPPAA-AVFTP-TLSDISIDKLKVSSPELPKPWGDGDLPLEEENPNS-P
Q-----EELHPRAIV-MSVAKDEEPES-MDFPAQPPPPE-PVPFMPFPAGTKAPSPSQMP
GSDSSTLESTLS-VTVTETETLDKPISEGEILFSCGQKLAPK--ILEDI--GLYLTNLND
SLSSTLHDAVEMEDDPPSEGQVI-RMSHKKFHADAILS-FAKQNQESAVSQQAVYHS--E
DLENSVGELSEGQRPQLTA-AAENILMGHS-LYMQPP-VTNTQSLDQQCDPKPLSRQFDT
V-SGSIYEDSCASHGPMSLGELELEPNSKLVLPTTLLT-AQENDVNLPVAAE--------
--------------------DFSQYQLK--QNQDVKQVEHK---PSQS-YLRVRNKSDIA
PSQ-QQVSP--GDMDRTQIELN-PYLTCVFSGLGVHVKKV----SCIGKLGLWRFVIQII
SS-----PRWESSATLRFTDAPCQDVSDAAVSEPRGLLSVSES--QHNAGGHGVFGGRYL
LNGKRQPAQCLCHWF

----------------------------MKGSEVS--------LEKKKRLKMPARRLREV
VSPNKGSNLPLLKDEL------PC-VPPALS-ANKRLAVRMGTP-DSGSLPGSSDLPSAR
SYHQPLL-E----KPTASE---SDFSKDVTMQE--LPLDKAEDSRR-KE

PF15324 // ENSGT00390000012397_0_Domain_2 (170, 1648)

DDI--FISQYT
VGQKDALRMALKQKA---------------------------------------------
-----QS------MPVFKEVKVHLLEDAGTEKGAA-PEEARISPSGINSATTVAAATAAA
IATAAPLIKVQSDLEAKVNSVTELLNKLQETDKHLKRVTEQQTSIQNK-QEKLHCH----
-DHEKQMNVFMEQHIRHLEKLQQQQIDIQTHFISAALKTGTC---PPDSLLPSRAMEKHS
IKP-EHLHLGSSVLSSHNTVASKQ----------------------------DTDFDELK
FPLETPAPRRFAPVPVSKDGEIS----KRENLKEEKENMEKSDH------GGNVRLLEQI
LNNNDFSTRKSES-SDITSLNTSKMGWNPERKDSFETLSSQ-RFPS-E----ELRMAKVT
MQKPNDVLHDLGQKKKETNGTLQPKKSLIML-----------------------------
----------------------KLA---DLPQNSG-KLQPTNTTRSILKDAEKILRGVQN
NKKVLEENLEAIIRAKDGAAVYSFINTLYTNREVSEKIRIKKTVDEWIKAISAEIQDEMI
RKDYEQRR---FDQKNQ--RTKKAQ-N----ISKDIKANMQDKT----VNKSIIPRK-PQ
KQVEDYLRSLHVR--GMAASSIQK-ERKEGLFKSSTEIQDEDYM-SQVYGKPVYQGHRST
LKRGPYLRFNSTSLKS-KPQRPKIIEQVKGTKVKSIRTQTDFHATKPVKIDSKMQHPVTA
-LPRGE-QQYLFSPSREMPTFSGTLEGHLIPMAILLGQTQSNSDSAPPAGVIVHKPHPVT
VTTSITP---SSGKVETVVKKTNIAVVEMKSEKKDPPRLTVQVLPRVDIDSISNSHTDGD
SPL-PSPGGGGGAC-LPPAQLCRQAPEFMNVDEEEEKFPGTNFDEVIDVIQEE-EKCDEI
PECSEPMLEFNRSVKVASTKYNGPPFPPVVSTSQP--TTDTLDKVIERKETLE--NNLIQ
WVEQEIMSRIVSERFVAPQ-QTRLAASVS-VSEASEPSTPDLVEGTCGGALQLFVDAGVP
VNSDTIRHLVNEALAETIAGMLGDRESKKQGPVATSVSGDVSTSETPL-LTRIGTPVATP
QPTPPRSPAS----PPKEYVLVKTPDSSPCSSYHDVAFPVKEISAA------KGMPAITL
VNTPTVIPAATTPPA--AALTP-TLSEVSIDKLKISSPELPTPWGAGDLPLDEENPHC-L
QE----ELLHPRAIV-MSVAVDEEPES-VDLLPLPAPAE-PVPPAPFPVGVKAPSSFQLP
SSGSSTLESTLS-VTVTDTETLDRPISEGEIVCNCGQRLDPR--R--DG--ELCLTHLHD
SFSSTAQDALDMEDDSPSEGQVI-RVFHKKFHTDSVRPLV-KQNQELLVLQ-----Q--A
DLENSMGELSEGQRPRLAA-AAENILLEQS-HYVQHC-IANAESVGQQWDPKPVFQQFDT
V-SGGVYEDSCASPGPMSLGELELQPHSSVVLPAALLR-TRGGDVRLPEAAE--------
--------------------DFSQNQQK--QDQDVKQVEHK---PVQSRLIHVRNISDIS
LSQ---------------------------QGGEAVPHCTSQRSP--------ARMSVTL
PAVNLEDCSPSLSV--------------------------GTIQGDPVSSGADTF-----
---------------

----------------------------MKGSEFS--------LEKKKKVKIPARRLREV
VSSSQGDNLALLKDKL------SC-VPPVLS-ANKCLPVRTGKS-SNGTLP---------
---------------------------DVAVQG--LPLDKTEENNRQ-A

PF15324 // ENSGT00390000012397_0_Domain_2 (170, 1649)

NDI--FISQYT
MGQKDALRAVLKQ-----------------------------------------------
---KAQS------MPVFKEVKVQLLEDASTEKDAV-TQENRTSPSGIDSATTVAAATAAA
IATAAPLIKVQSDLEAKVNSVTELLNKLQETDKQLQRVTEQQTSIQSK-QEKLHCH----
-DHEKQMSVFMEQHIRHLEKLQQQQIDIQTHFISAALKTSSF---QPITGPPSRSVEEYS
VKP-DHVNFGSCNLSSDNTFASKQ-------------------------EVEDMNFDKQK
SPLETPTPRRFAPVPVSKDDKIS----KRENPMEEKENMEMSHH------TGNIRLLEQI
LNNPDSLTRISES-SGKTPLTRSKLGWQPERRNSIDTLSTQ-RFPSYE----ELGRAKVT
MQKSDDILHDLGQNKKETNGILQPKESQIVS-----------------------------
----------------------RLA---DLPQNSI-KLQTT-STRSVLKDAEKILRGVQN
NKKVLEENLEAIIRAKDGAAMYSFINALSTNREIPEKIRIRKTVDDWIKTISAEIQDELA
RKDYQQKK---FDQKNQ--RTKRTQ-N----MSKDIKTNTQGKT----VNNSLFPRRHSQ
RPKEECFRNPPTR--SMAASSLPK-ERKEGLLKATTEVQDNDYT-LQIYGKPVYQGHRST
LKKGPYLRFNSPSPKF-RPQRPKVIERVKGTKVKSIRTQTDFYATKPTKVDSKLQHSITT
-LSPGD-QQYLFSPSREMPTFSGTLEGHLIPMAILLGQTQSNSDSMPPAGVIINKPHPIT
VTTSIPP---SLRKTETRVKKPNIAVVEMKSEKK----ILLSLLYSVDIDSISNGSVDIG
LSP-SSL---KEAS--PPLKTWIQTPEFMKADE-EVKFPGTNFDEVIDIIQEE-EQCDEI
PEYSEPILEFNRSVKVVSTKYNGPPFPPVASTVQP--TADVLDKVIQRKETLE--NSLIQ
WVEQEIMSRMISRLLPVQQ-QATANVSVS-VSEASEPSTSDIVEGTSSGALQLFVDAGIP
VNSDMIRHFVNEALAETIAVMLGDGEAKKQGPVVTSISGDVST--AHL-PARACTPLPTP
QPTPPCSPSP----LPKECVLVKTPDSSPCVSDHDVALPVKEIFAEE----GNDMPGITL
VNTPAVTPATTPPPAA--VLTP-TLSETSIDQLKISSPELPKPWGDRDLPLEEENPSS-L
QE----E-LHPRAIV-MSVAKDEEPES-MGVPVQPPPPE-PVPVMALPTGTKAPAPTQMP
SLDSSTTESTFS-ITVTETEPIDRLLSEGEILLNCGQKVVPK----RDE--GLYMTNLND
SLSSTLQDALEMEDDPPSEGQVT-RMSYRKIHADAILSLRAKQNQESLVQQQA-------
NLENSVDELSGGQRPSLT---AENILLGHS-AYTQEP-VANTESSDQKCAPKPLSQQCDT
V-TGGVYEDSCASHGPMSLEELELQPHPHVALPKTLLT-AQENDVKLSVAAT--------
--------------------DFPQYQQK--EDQDVKQVEHK---PVQSRLIHVRSKSDIS
LQP-Q-------------------------QSGKAVPLFTPQMSP--------PRMSLTV
PSVNLEDGAQSLSI--------------------------NTIQGDTESSGADTF-----
---------------

----------------------------MKNVEFS--------LDRGQRLKMPARKLREI
VSPNHGNKLAVVEDEL------PR-VPPALA-ANKRLAVEARTS-SNGTLCGPLDLTSAR
HYHQPLS-E----SPPASKK--SDFSKDAVVRR--VPSNKTEESNAPKA

PF15324 // ENSGT00390000012397_0_Domain_2 (170, 1644)

NDI--FISQYT
MGQKDALRTVLKQKA---------------------------------------------
-----QS------MPVFKAVKVHLLEDTGTEKNPV-AQKTETPPNRIDSATTVAAATAAA
IATAAPLIKVQSDLEAKVNCVGELLTKLQETDKQLQRVTEHQASVQSK-QEKVHCH----
-DHEKQMNVFIEQHIRHLEKLQQQQIDIQTHFIDAALKASSL---Q-LGVSTSRAVEKYS
GKP-GSPSVGS-SVFSHNTFVSKQV---------------------PLG--EDTDFDGQK
SPLETPAPRRFAPVPVSRDGKIT----KRESPTEEKENMEMYSP------KGNVRLLEQV
LNSNECLTRKTDS-SDITSLTQPKMGWNFEKRDSTETLHSQ-RFPSSE----EQGTAQIP
VQKYNDDVHDLGQKKKQTCDMLQIKQSPVTL-----------------------------
----------------------RLS---DHPHGPA-MLQTA-NTRSILKDAAMILRGVQN
NKKVLEENLEAIVRAKDGAAVYSFINALATNREMSEKIRIRKQVDEWIKIISAEIQDELM
RKDYEQKR---FDPKNQ--RNKKAL-T----MSRDIRANNQDKL----VNRSVIPRSHYQ
KQTQEQFTSPPVR--SLPASGPQK-ER-NGLLKSTTTLQDEDYM-LQIYGKPVYQGHRST
LKKGPYLRFSSPSPKA-KPQRPRVIELVKGTKVKSARTQTDFHAASRMKMDSKIQHPITT
-LPHAD-QQCMFSPSREMPTVSGTLEGHLIPMAILLGQTQSNSDSMPPAGVTVNKPRPMT
VTTSIPP---ASRKGNTGVKKPNVAIVEMKSEKKDPPQLSVQVLPSVDIDSISYSSTDGA
SPS-PSP---KEAS-LPPLHTWIQTPDFIKEDEEEMPLPGTNFDDIIDVTQEE-EKRDEI
PECSAPMLEFNRSVKDVPTKYNGPSFPPVVSAYHP--TTDILDKVIERKETLE--NSLIQ
WVEQEIMSRIISGLFPLQQ-QARLDASVS-VSEASEPSASDIVAGRSSGALQRMVDARVP
VNSDLVSHFVNEALTETIAVMLADREAERQRPAATSVPGDPSGAETNL-SARVCALVATP
QPTPPCSPS-----PVKEHVLVKTPDSSPCESDPDVASSLKEIRVEK----GSDMPAVML
VSTPTRTPVTTPPPAA--ALTP-TLSEISIDKLKLSSPELPKPWDSGDLPLDEENPNS-L
QE----L-PHPRAVV-M-SVANEEPES-MDFSAQPAPPE-PAPSAPLPEGTKAPSLQRIP
SSGSSTLENTLS--TVTETETLDRHISEGEILFSCGQNLATK----RPG--DLFLMNIND
SLSSTLQDALEMEDDPPSEGQVI-RRPHKKRHEEAIIALLTKQERELLVSQQE------E
GLDTSVGELSEGQKLVLKA-A-QDVSAGSS-GRTLQP-TSPAEPSCQHTDPRLVLQQSHM
A-SGNICEDLCASHGPMSLRELELQPDSNLILPLTHTT-TKVSDVNLPEAAE--------
--------------------DFSQYQQK--QDSDIKQVEHK---PIQRHLTCMRNKSDSS
LSQH--------------------------QGGPADPLLIAHVSP--------ARMSVTL
PSANLEDCSQSLST--------------------------SSMHGGAESSGTDTF-----
---------------

MEAESGSSTSQDSLASLTAGDVLVRSTGVRGVKGAAG------AGGRNSAAVSVTKLREA
LPSRQAAGVALS------RGETPC-EPPV-P-SSGASNGR-VTGV-TACSAAPGVWNAKG
HPEHLLLVADPVEATSVPQ---MVYPKEAAVNPKEADRSLQPEYSRRPK

PF15324 // ENSGT00390000012397_0_Domain_0 (170, 437)

DDV--LISRYP
TGQKEALRAVLKQKT---------------------------------------------
-----RS------APVFKEVKVQLLGNASPERKESVGQDPILTHREADSATTIAAATAAA
IATTAPLLKVQNDLQAKVNCVSTLLHKLQETDKQLQRVAEQQTNTKTQH-EKPHCH-ERV
SELEKQMNAFMLQRIHHLEKLQEHQMNIQSHFISSAVNMGGL---QQTHMPSSGLLTKQS
EKAEEQLLNN-GISSS

ENSGT00390000012397_0_Linker_0_2 (437, 447)

QKNFFPSSGL

PF15324 // ENSGT00390000012397_0_Domain_2 (447, 1649)

PTQ--G----------------------------
----------------------------------------------------DGRHLEHI
LNPQAAPWGQMES-SEKTMLTNDKMSWHSEIERPTALQ-T-DSCPAYENSSQNCNSIEKT
VKKADDLLQVLGQLRKEMHDMLQEASSWKSDMNDLIKSK---------------------
----------------PATIASDPPEYNHLVKPS--VLQNVKAPNSILSDAKRVLREVQS
RKKVLEENLEAVLRAKGGGAMSAFINALTTNRDALEKIRIRKAVDERIKAISAEIQAEMA
RNDMEQVK---YDQKVP--WIKRAQNIKAMKNSKEIKAKTQKIQGC-STKKPLSAAKSLR
NHVEDNISKEGFRTYFSSESLQRNRKGTDEPMSGCAMVQNEEYL-SQIYGKPIYQGHRST
LKKAPYLRFNSPSPKS-KLQRPRVIEYVRGTKVKSAGTQTCSRAQKAVI-SSKKQHPLYA
---LAQENQYFFSPNRDVPADCGPLEGHLIPMAVPLGQTQINDISVQPAGVVMCKPHPVT
VTTSIPQVPP---KPPTEVKKPNVAVIEMRSEKKDPPQLSVQVLPNVDIDSISGGSVSVN
HVLPEPK------PARCPADAVIQAPEDIQSEEEDVKFPGTNFTDVTDVVQDQEEERDEI
PEFTEPLLEINGHFRVAEPTYNGPSFPPVASAPQQ--SCDVLDEWIERRETIE--NRLIN
WVEQEIMAKIISEMYPVQR-ETVPSVSTS-EGEDSETVTSDIVEAAGGGGFQLFIDAGVP
VDSEMISHLVNEVLSETIATMLGNRQAQEAVPATNLLPSTTA-----VMEPLVPTPLPTP
QATPPQTPPS-----EKEMPPVQTPESSPSITELSGDVREQEKMKEAG---SDIPAAVSR
VGTPVITPISTPPEII--TPSP-PAS----EAAKMENPAPLNPWDDAELPLEEEKPSPLA
EE----T-FNPKAVE-MSVANDEEPEA-LILPSWQSSPK---PFQSLPCEPEAPSAAPTD
SSEQSTQESSL---TPTETETADRPISEGEVLFSCDQMLAAR-----EG--GLSFPNLTE
SLTSTLQDANEMDYDPPSEGQVV-RRSHKGYHRDPVLALLAKLNQAPVAVQEGGYHL--E
DSDSSVGELSEGQRPRLTR-AAERILMGHP-VDIDHATARASEDRPYQGSRSPSPGQLTH
--PAEILGDADTSHGPMLVAELESQPISNPVLQAAQPSCRVAS---LPK-----------
--------------------GPSQEESQ--G--------DAR--VVRPRVVHVRRKSEEM
QEE-----GEG-----------------------VVPHFHSHVSA-------ER-MSVKL
PSMNIDDQTQSL----------------------------SSIHGDSDSSGADTF-----
---------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------

PF15324 // ENSGT00390000012397_0_Domain_4 (1049, 1647)

MKSEKKDPPQLSVQILPSVDIDSISYSSVDRL
SSP-PSP---KEAS-LPPLHTWIQTPEFMKVDEEEAKLPGTDFDEVIDVIQEE-EQRDEI
PECSAPVLEFNRSVKVIPTEYNGPSFPPVVSTFHP--TTDILDKVIERKETLE--NSLIQ
WVEQEIMSRIISGLFPLQQ-QARLDASVS-ISEASEPSASDIVVGTSSGALQLFVDAGVP
VSSDMISHFVDEALAETIAVMLGDREAKKPRPVATSVSGDPSTNETNL-PVRVCTPVATP
QPTPPCSPP-----PPQEPVLVKTPDSSPCDSDQDVASPLKEICAEK----GSDVPAITL
VSTPVVTPVTTPPPAA--ALTP-TLSEISIDKLKLSSPELPKPWDSGDLPLDEENPNS-V
EE----L-VHPRAIV-MSVAKDEEPGS-VDFPAQPAPLE-PAPLTPLPEGTKAPSARQMP
SSGSSTLENSLS-ISATETETLDRHISEGEILLSCGQNLANK----RNG--DLHLLNVND
SLSSTLHDAFDMEDDPPSEGQVI-RRPHKRLHPNAILSLFTKQEQEFLVSQQA------E
DLDNSVGELSEGQRLVLTA-A-EDILAGAS-VCVLQP-TPTAEPSDRRADPGMLLQPD--
------------------------------------------------------------
------------------------------------------------------------
--MA--------------------------TGGETIPLFTAHTSP--------AKMSVTL
PSANLDNCSQSPST--------------------------STVQGDEESSGTDTF-----
---------------

------V--------LK-CGTCFVT-NNMKGSEVS--------LEKKKRIKMPAKRLREV
VSQNHGDHLVLLKDEL------PC-VPPALS-ANKRLPVGTGTS-LNGTSRGIPYLF---
----------------KFP---NDFSKDVAVQV--LPLDKIEENNKQKANDI--FISQYT
MGQKDALRTVLKDGVSLCWPGWLECSGVITTHCSLYL---------LRLMRSSHLSLPSS
WDYRSQSM------PVFKEVKVHLLEDAGIEKEAV-TQETRISPSGIDSATTVAAATAAA
IATAAPLIKVQSDLEAKVNSVTELLSKLQETDKHLQRVTEQQTSIQRK-QEKLHCH----
-DHEKQMNVFMEQHIRHLEKLQQQQIDIQTHFISAALKTSSF---QPVSMPSSRAVEKYS
VKP-EHPNLGSCNPSLYNTFASKQA---------------------PLKEVEDMSFDKQK
SPLETPAPRRFAPVPVSRDDELS----KRENLLEEKENVEVSCH------RGNVRLLEQI
LNNNDSLTRKSES-SNTTSLTRSKIGWTPEKTN---------RFPSCE----ELETTKVT
MQKSDDVLHDLGQKEKETNSMVQPKESLSML-----------------------------
----------------------KLP---DLPQNSV-KLQTSNTTRSVLKDAEKILRGVQN
NKKVLEENLEAIIRAKDGAAMYSLINALSTNREMSEKIRIRKTVDEWIKTISAEIQDELS
RTDYEQKR---FDQKNQ--RTKKGQ-N----MTKDIRTNTQDKT----LNKSVIPRKHSQ
KQIEEHFRNLPMR--GLPASSLQK-ERKEGLLKATTVIQDEDYM-LQVYGKPVYQGHRST
LKKGPYLRFNSPSPKS-RPQRPKVIERVKGTKVKSIRTQTDFYATKPMKMDSKMKHSVPV
-LPHGD-QQYLFSPSREMPTFSGTLEGHLIPMAILLGQTQSNSDTMPPAGVIVSKPHPVT
VTTSIPP---SSRKVETGVKKPNIAIVEMKSEKKDPPQLTVQVLPSVDIDSISNSSADVC
SPL-SSP---KEAS-LPPVQTWIKTPEIMKVDEEEVKFPGTNFDEIIDVIQEE-EKCDEI
PD-SEPILEFNRSVKADSTKYNGPPFPPVASTFQP--TADILDKVIERKETLE--NSLIQ
WVEQEIMSRIISGLFPVQQ-QIAPNISVS-VSETSEPLTSDIASPETPV-----------
---------------------------------ATGPCFF-A

PF15324 // ENSGT00390000012397_0_Domain_6 (1303, 1649)

SLSPSM-TARVCTPLATP
QPTPPRSPSS----PTKECVLVKTPDSSPSDSDHDMAFPVKEICAEK----GDDMPAIML
VNTPTVTPTTTPPPAV-AVFTP-TLSDISTDKLKVSSPELPKPWGDGDLPLEEENPNS-P
Q-----EELHPRAIV-MSVAKDEEPES-MDFPAQPPPPE-PVPFMPFPAGTKAPSPSQMP
GSDSSTLESTLS-VTVTETETLDKPISEGEILFSCGQKLAPK--ILEDI--GLYLTNLND
SLSSTLHDAIEMEDDPPSEGQVI-RMSHKKFHADAILS-FAKQNQESAVSQQAVYHS--E
DLENSVGELSEGQRTQLTA-AAENILMGHS-LYMQPP-VTNAQSLDQQCDPKPLSRQFDT
V-SGSIYEDSCASHGPMSLGELELEPNSKLVLPTTLLT-AQENDVNLPVAAE--------
--------------------DFSQYQLK--QNQDVKQVEHK---PSQS-YLRVRNKSDIA
PSQ-QQVSP--GNMDQTQIELN-PYLTCVFSGLGVHVKKV----SCIGKLRPWRFVIQII
SS-----PRWESSATLHFTDAPCQDVSDAAVSEPRGLLSVSES--QHNAGGHGVFGGRYL
LNGKRQPAQCLCHWF

---------------------------------------------------IPPRRLREV
DSPNHGDNLALLKDEL------PC-VPPALP-ANKRLPVRTRTS-LNGTSCGSSDLTSAR
NYHQSSL-E----NPTASE---SDFSKDIAIQG--LPLDKTEESNRQKA

PF15324 // ENSGT00390000012397_0_Domain_0 (170, 310)

NDV--FISQYT
MGQKDAVRTVLKQKA---------------------------------------------
-----QS------MPVVKEVKVHLLEDAGTEKDAA-AQETRTSPSGIDSATTVAAATAAA
IATAAPLIK

ENSGT00390000012397_0_Linker_0_2 (310, 395)

VYLSPQIF-------------------------------------------
------------------------------ITTF

PF15324 // ENSGT00390000012397_0_Domain_2 (395, 1649)

AALKTSSF---QPVSVPPSRAVEKYS
VKP-EHPNFGSSNLSSPNTFASKQA---------------------PLREVEDTGFDKQK
SPLETPAPRRFAPVPVSRDSELS----KRENPMEEKENMELSGH------RGNVKLLEQI
LNNNDSLTRRSEF-SDNTSLTGPKIGWNPEKRD---------RFSSHE----ELGTVKMT
MQKSNDVLHDLGQKKKEANGMVQND-----------------------------------
------------------------------------KLQTTHTTRSVLKDAEKILRKVQN
NKKVLEENLEAIIRAKDGVAMYSFINALSTNREMSEKIRIRKTVDEWIKTISAEIQDELS
RKDHEQKR---FDQKNQ--RTKKVQ-N----MSKDLKTNTQDKT----VKKPVIPGKYSQ
KQIEEHFRNLPMR--SMPASSLQK-GKKEGLLKTTTVIQDEDYM-LQVYGKPVYQGHRST
LKKGPYLRFNSPSPKS-KPLRPKVIEQVKGTKLKSIRTQTDFYAAKPMKMDSKMKHSITT
-LPHGD-QQYLFSPSREMPTFSGTLEGHLIPMAILLGQTQSNSDSKPPAGVIVNKPHPIT
VTTSIPP---SSRKIESGVKKPNIAVVEMKSEKKDPPQLTVQVLPSVDIDSISNGSADVD
PPL-PSP---KEAS-LPPLQNWIQTPEIMKIDEEEVKFPGTNFDEVIDIIQEE-EKCDEI
PD-SEPIMEFNRSVKVVSTKYNGPPFPPVASASQP--TADILEKVIERKETLE--NSLIQ
WVEQEIMSRIISGLFPIQQ-QAIHNVSVS-VSEASEPLTSDIVEGTSGGTLQLFVDAGVP
VNSDMISHFVNEALAETIAVMLGDREAKKQDPVATSVDGDVSANETYL-PARVCTPVATP
QPTPPHSPSS----PPKEHVLVKTPDSSPCVSDHDVSFPTKEIFAEK----GNDMPAVTL
ITTPAVTPTATPPPA--AALTP-TLSEISIDKLKVSSPELPKPWGDGDLPLEEENPNP-L
QE----ELLHPTAIV-MSVAKDEEPDSVLDFPAQPAPPE-PVPVTPFPAGSKAPSPPQMP
NSDSSTLESTLT-VTVTETETLDRPISEGEILFSCGQKLAPK--ILGDD--GLYLTNLND
SLSSTLHDVLEMEDDSPSEGQVI-RMPHKKSHADVILSLLAKQNQESLILQQAVCHS--E
DLENSVGELSEGQRPRLTA-ATENILLGHS-FYGQQP-VANAETLNQQCDSKPLPQQFDT
V-SDGIDEDSCASHGPMSLGELELQPNSNFVLPTTLLP-AQENDGNLPGAAE--------
--------------------DFSQYQQK--QDHDVKQVEHK---LAQSCLIQ--------
------ASP--GDMDRTQIEPN-LYLASVFTGGKAVPLLTSQTAP--------AKMSVTL
PSVNLEDLSQSQSI--------------------------STIQGDMESSGTDTF-----
---------------

---------------IHNCGTSFVT-RNMKGAEFS--------PEKKRRVKIPARRLREV
VSPNQGENLALPKEEL------PC-VPPALS-ANKRLPLRTEAS-LTGTLRGSSDLTSAR
NYQQPPL-E----ISTVSE---SDFSKDVAVQE--LPLDKLEESNRQKANDI--FISRYT
MGQKDALRAVLKQNLQFPVCNMVVRRGILMVNCILGLIYIE------KN---THSSVIRE
FVY

PF15324 // ENSGT00390000012397_0_Domain_2 (244, 1648)

RAQN------MPVFKEVKVQLLEDAGTGKDAA-TQEMRTSPSGIDSATTVAAATAAA
IATAAPLIKVQSDLEAKVNSVTELLNKLQETDKQLQRVTERQTSIQNK-HEKLHCH----
-DHEKQMNVVMEQHLRHLEKLQQQQIDIQSHFISAALKTSNF---QPVAVPASRVMEKYS
VKP-DFSNLGSSNLSSHNTFASKQV---------------------LSREVEDTDFDKQK
SPLETPAPRRFAPIPVSKDDKIS----KRENPKEEKENMEMTDH------TENIRLLEQI
LSNHDSLTRKSEP-SDKTSLTRSKIGWNPERRD---------RFPFYE----ELGAANLT
VQGSDDFLHDPGQKRKETNGILQPKESLIMS-----------------------------
----------------------RLA---DLPQNSI-KLQTT-NKRSILKDAEKILRGVQN
NKKVLEENLEAIIRAKDGAAMYSFINALSTNREMSEKIRIRKTVDEWIKTISAEIQDELA
RKDYEPKR---FDQKNQ--RTKKAQNN----MSKYIKTNIQDKT----VNSSVIQRKHPQ
KQKEEHFRNPPMR--SMPASNLQK-ERKQGFLKATAVLQDEDYM-LQIYGKPIYQGHRST
LKKGPYLRFNSPSPKS-KPQRPKVIERVKGTKVKSIRTQTDFYATKPVKMDSKPQHSVTT
VLPPGD-QQYLFSPSREMPTLSGTLEGHLIPMAILLGQTQSNSDSMPPTGVIINKPHPVT
VTTSIPP---SSRKMETGIKKPNIAIIEMKSEKKDPPQLTVQVLPNVDIDSISNGSADVD
LSV-PSP---KEES--PPLKTWIQTPEFTKVDEEEVKFPGTNFDEVIDIIQEE-EKHDEI
PEYSEPILEFNRSVKVVSTKYNGPPFPPVASTFQP--TTDTLDKVIQRKETLE--NSLIQ
WVEQEIMSRIISGLFPVQQ-QTIPNVSAS-VSEASESLTSDVVEGTSGGALQLFVDAGVP
VNSDMISHFVNEALAETITVMLGDREAKNQGPIATSVSGDVSISNTHL-PARICTPVATP
QPTPPRSPSS----PPKERVLVKTPDSSPCDSDHDLSIPEKEILAEK----GNEVPAITL
VTTPVVTPATTPPPAA--ALSP-SLSEISIDKLKLTGPEFPKPWSDGDLPLEEENPNS-P
QE----E-LHPRAIV-MSVAKDEEPES-VDFPPQPAPPEL-----PLPTGTKTLPPTQMP
GSDSSTTESTLS-VTVTETETLDRPISEGEVLLNYGQKVAPK--ILGDG--RLYLMNLND
SLSSTLHDALEMDDDPPSEGQVM-RIPHKKIHADAIPSLLAKENQDSLVSPQAAYHS--E
DLENCAGELSEGQRPGLTA-AAENIFPGRS-VSMQPP-ATNVGSLGEKCAPKPLSQQFDT
V-TGAGYEDSCASHGPMSLEELEFQPNSNLALPTTLLT-AQENDVKLSGAAE--------
--------------------DIHQYQQK--HDQEHKQVEHK---PAQSRLIRVRNKSDTS
FSQ-QQ------------------------------------------------------
------------------------------------------------------------
---------------

----------------------------MKGFEFR--------LEKEKGVKMPARRLREV
LSPNQGDSLPLVKDEF------PG-VPPALP-ANKRLPVGTRTS-LNRTLCGSSDLTSRK
-YYHPLS-E----NPTVSNK--SDFSKNV-VTN--LSSEKTEDSNRQKA

PF15324 // ENSGT00390000012397_0_Domain_2 (170, 1649)

NDI--FISQYT
LGQKDALRTVLKQKA---------------------------------------------
-----QS------MPVYKEVKVHLLEDTRTEKDGV-AQETRTSPSRIDSATTVAAATAAA
IATAAPLIKVQSDLEAKVNSVTELLNKLQETDKQLQRVTEQQTSIQTK-QEKFHCH----
-DHEKQMNVFMEKHMRHLERLQQQQIDIQTHFISAALKTSSF---QPVGTSPSRAVETYS
VRS-AYPHLESNSLSLQNTFPSKQV---------------------PLREVEDTDFDGKK
SPLETPAPRRFAPVPVSRDEKIS----KREDPIEEKENMELSGY------RGNVRLLEQI
LNSNDSLTRKSES-SDITSLTRSKMGWNSEKRESTETLPSQ-RFPSYE----ELGAANVM
TQKHDGVVHGLGLKKKERNGTFQPKQSPIIL-----------------------------
----------------------RLS---NLPQNSV-KLQTA-DTKSVLKDAEKILRGVQN
NKKVLEENLEAIIHAKDGAAMYSFINALS-NREMSEKIRIRKKVDEWIKIISAEIQEELT
RKDYEQER---FDLKSQ--RTRKAQ-S----LSRAIKTNTQDTP----VNKSIIPRQHSQ
KQIQERFRSPP------------------GLLKSTTVKQDEAYM-LQVYGKPVYQGHRST
LKKGPYLRFSSPSPKI-RPQRPKVIERVKGTKVKSARTQTEFYAVKPMKMDSKIQQPIIT
-LPPGD-QQYLFSPSREMPTISGTLEGHLIPMAILLGQTQSNSDSMPPAGVIVNKPHPVT
VTMSIPP---STRKVEAGIKKPNIAVVEMKSEKKDPPQLSVQVLPSVDIDSISYSSSDGG
SPS-PSP---KQAP-SPPLHTWIQTPEFVEADEEEVKFPGTNFNEVIDV-QEE-EKCDEI
PEYSEPMLEFNRSVKLVSTKYNGPPFPPVVSTFQP--TTEILDKVIERKETLE--NSLIQ
WVEQEIMSRIVSGLFPLQH-QARLSTSIS-VSEASGSSTSDIVAGTSSGVLQLFVDAGVP
VNSDLISHFVNEALAETIAVMLGDREAKKQGPAALSAAGDVSASETYL-SARVCTPVATP
QPTPPGSPS-----PPEEHVLVKTPDSSPCDSAYDVAFPVKEVCAEK----GDNIPTITL
VNTPTVTPITTPPPPA--APTP-TLSEISIDKLKLSSPDLPKPWDNGDLPLDEENPNS-L
QE----L-LHPKAIV-MSVAKDEESAS-VDFSALPAPSE------PLPMDTKAQSPIQMP
SSGSSTLENTLS-ITVTDTETLDRPISEGEILFSYGQNLATK----RNG--GLCLMNVND
SLSSTLHDALEMEDDPPSEGQVI-RMPPKKFHADAILSLLTKQDQELLVLQQT------E
DLDNSVGELSEGQRPRLTV-AAENILTGQS-VCLQQP-AASAEFLDQEGDPRLLLQQSDI
A-SGNICDDSCASHGPMSLRELEFQPNSNPVLTATHLT-T-ENDVNLAEAAE--------
--------------------DFSQYQRK--QDTAVKQVEQK---PVQSHLIRIRNKSDVS
---S--------------------------QGAGPVPLFTSQTSP--------TKMSVML
PSANFEDCSQSPSV--------------------------SIIQADMESSGTDTF-----
---------------

----------------------------MKGSEVS--------LEKKKRIKMPAKRLREV
VSQNHGDHLVLLKDEL------PC-VPPALS-ANKRLPVGTGTS-LNGTSCGSSDLTSAR
NCHQPLK-E----NPLVSE---SDFSKDVAVQV--LPLDKIEENNKQKA

PF15324 // ENSGT00390000012397_0_Domain_2 (170, 1649)

NDI--FISQYT
VGQKDALRTVLKQ-----------------------------------------------
---KAQSM------PVVKEVKVHLLEDAGIEKDAV-TQETRISPSGIDSATTVAAATAAA
IATAAPLIKVQSDLEAKVNSVTELLSKLQETDKHLQRVTEQQTSLQSK-QEKLHCH----
-DHEKQMNVFMEQHIRHLEKLQQQQIDIQTHFISAALKTSSF---QPVGMPSSRAVEKYS
VKP-EHPNLGSCNASLYNTFASKQA---------------------SLKEVEDMSFDKQK
SPLETPAPRRFAPVPVSRDDELS----KRENLLEEKENMEVSCH------RGNVRLLEQI
LNNNDSLTRKSES-SNTTSLTRSKIGWTPEKTNSVETLPSQ-RFPSCE----ELGTTKVT
LQKSDDVLHDLGQKEKETSSVVQPKESLSML-----------------------------
----------------------KLP---DLPQNSV-KLHTTNTTRSILKDAEKILRGVQN
NKKVLEENLEAIIRAKDGAAMYSLINALSTNREMSEKIRIRKTVDEWIKTISAEIQDELS
RTDYEQKR---FDQKNQ--RTKKGQ-N----MTKDIRTNTQDKT----VNKSVIPRKHSQ
KQIEEHFRNLPTR--GMPTSSLQK-ERKEGLLKATTVIQDEDYM-LQVYGKPVYQGHRST
LKKGPYLRFNSPSPKS-KPQRPKVIERVKGTKVKSIRTQTDSYATKPMKIDSKMKHSVPM
-LPHGD-QQYLFSPSREMPTFSGTLEGHLIPMAILLGQTQSNSDTMPPAGVIISKPHPVT
VTTSIPP---SSRKVETGVKKPNIAVVDMKSEKKDPPQLTVQVLPSVDIDSISNGSTDVG
SPL-SSP---KEAS-LPPVQAWIKTPEIMKVDEEEVKFPGTNFDEIIDVVQEE-EKCDEI
PD-SEPILEFNRSVKADSTKYNGPPFPPVASTFQP--TANILDKVIERKETLE--NSLIQ
WVEQEIMSRIISGLFPIQQ-QIEPNISVS-VSETSNPLTSDIVEGTSGGALQLFVDAGVP
VNSDVINHFVNEALAETIEVMLGDREAKKQGPVATGVSGDASTNETYL-PARVCTPLATP
QPTPPCSPSS----PTKECVLVKTPDSSPCDSDHDMTFPVKEIYAEK----GDDMPAITL
VKTPTVTPTTTPPPAV-AVFTP-TLSDISIDKLKVSSPELPKPWGDGDLPLEEENPNS-P
Q-----EELHPRAIV-MSVAKDEEPES-MDFPAQPPPPE-PVSFMPFPAGTKAPSPSQMP
GSDSSTLESTLS-VTVTETETLDKPVSEGEILFSCGQKLAPK--ILEDV--GLYLTNLND
SLSSTLHDAVEMEDDPPSEGQVI-RMPHKKFHADAILSVLAKQNQESAVSQQAVCHS--E
DLENSVGELSEGQRPQLTA-AAENILMGHS-LCMQPP-VTNVQPLDQQCDPKPLSRQFDA
V-SGSIYEDSCASHGPMSLGELELEPNSNLVLPTTLLT-LQENDVNLPVAAE--------
--------------------DFSQYQQK--RNQDVKQVEHK---PSQS-YLHVTNKSDIA
PSQ-QQVSP--GDMDQTQNELN-PYLTCVFTGGKAVPLSA----SQM---PPAKVSMTLP
SV-----NLE-----------DCSQS--------LSIS--------TMQEDVESSGADTF
---------------

----------------------------MKGSEFC--------LEKKKKVKVPARRLREI
ASPNQGDNLALLKDEL------SR-VPPALS-ANKRLPVRTGKS-LNGTLCGIIFLCF--
---------------------------------------------YFAA

PF15324 // ENSGT00390000012397_0_Domain_2 (170, 1648)

NDI--FISQYT
MGQKDALRAVLKQ-----------------------------------------------
---KAQS------MPVFKEVKVQLLEDAGTEKDPV-TQENRISPSGIDSATTVAAATAAA
IATAAPLIKVQSELEAKVNSVTELLNKLQETDKQLQRVTEQQTTMQNK-QETLHCH----
-DHEKQMNVFMEQHIRHLEKLQQQQIDIQTHFISAALKTSSF---QPVIIPPSRAVEKCS
VKP-DHLNFGSSTLSSHNVFSSKQ-------------------------EVEDTSFDKQK
SPLETPAPRRFAPVPVSKDDKIS----KRENPTEEKENMELPCH------TGSVGFLKQI
LNNRDSLTRISES-SDKTSLARSKMGWNPERRNSIDTIATQ-RFPSYE----ELGTAKVT
VQKSDDILHELDQKRKETNSILQLKESQ-MS-----------------------------
----------------------GLA---DLPQNSI-KLQIT-NTRSVLKDAEKILRGVQN
NKKVLEENLEAIIRAKDGAAMYSFINALSNNREISEKIRIKKTVDDWIKTISAEIQDELT
RKDYEQKR---FDQKNE--RNKRAY-N----MNKYIKTNTQDKT----VNNSVIPRKHSQ
KQKEDRLRNPPIR--SMPASSLQR-ERREGFLKATTVVQDKDYM-LQIYGKPVYQGHRST
LKKGPYLRFNSPSPKS-RPQRPKVIERVKGTKVKSIRTQTDFSATKPTKVDSKLQPSITT
-LSPGD-QQYLFSPSREMPTFSGTLEGHLIPMAVLLGQTQSNSDSMPPAGVIVNKPHPVT
VTTSIPP---SSRKIEPGVKKPNIAVVEMKSEKRDPPQLSVQVLPNVDIDSISNGSAEVG
LSP-SSP---KEASS-PPLRTWIQAPEFTKADEEEMKFPGMNFDEVIDIVQE--EKCDEI
SEYSEPILEFNRSVKAVSTKYNGPPFPPVASTFQP--TTDTLDKVIQRKETLE--NSLIQ
WVEQEIMSRMISGLLPVQQ-QATANVSVS-VSEASEPVTSDIVEGTSSGALQLFVDAGVP
VNSDMIRHFVNEVLAETIAVMLGDREAKKPDPVVTGCPYL-GIISTTY-LARVCTPLATP
QPTPPRSPSS----PPKEHVLVKTPDSSPSVSDHDVAFPMKEILAEE----GNDMPAITL
VNTPAVTPVTTPPPAA--ALTP-TLSETSVDKLKMSSPELPKPWSDRDLPLEEENPNS-L
QE----E-LHPRAII-MSVAKDEEPES-EDFPAQLAPPK-PVALMSLPAGIKAPSPIQMP
SSDSSTVESTLS-VTATETETLDRPISEGEILFNCGLKVAPK----RDE--GLYLANLND
SLSSTLQDALEMEDDPPSEGQVI-RMPHKKVHADAILSLLAQQNPESLISQQ--------
DLENSVGELSEGQRLPA-A-AAESVFMGLS-AHAQQP-VARAESSGAKCALKPSSQQ---
--PDAVYEDLCASHGPMSLGELELQPDPPVTLPTTLLT-AQESDVKLSEATE--------
--------------------DFPQYQQK--QDQDVKQVEHK---PIQSRLIRVRNKSDIS
LSQ-Q-------------------------QGGKAVPLFTSQTSP--------AKMSVTL
PSVNLEDCSQSLSI--------------------------GTVQADTESSGTDTF-----
---------------

---------------------------------------------------MPAKRLREV
VSQNRGDHLVLLKDDL------PC-VPPALS-ANKRLPVGTGTS-LNGTSRGIPYLF---
----------------KFP---DDFSKDVAVQV--LPLDKIEENNKQKA

PF15324 // ENSGT00390000012397_0_Domain_2 (170, 1649)

NDI--FISQYT
MGQKDAVRTVLKQ-----------------------------------------------
---KAQSM------PVVKEVKVHLLEDAGIEKDAV-TQETRISPSGIDSATTVAAATAAA
IATAAPLIKVQSDLEAKVNSVTELLSKLQETDKHLQRVTEQQTSIQRK-QEKLHCH----
-DHEKQMNVFMEQHIRHLEKLQQQQIDIQTHFISAALKTSSF---QPISMPSSRAVEKYS
VKP-EHPNLGSCDASLYNTFASKQA---------------------SLKEVEDTSFDKQK
SPLETPAPRRFAPVPVSRDDELS----KRENLLEEKENMEFHYV------SQAGHK---L
LGSSDLPTSASQS-AGITDV---------SHCACVETLPSQ-RFPSCE----ELGTTKVT
LQKSDDVLHDLGQKEKETNSMVQPKESLSML-----------------------------
----------------------KLP---DLPQNSV-KLHTTNTTRSVLKDAEKILRGVQN
NKKVLEENLEAIIRAKDGAAMYSLINALSTNREMSEKIRIRKTVDEWIKTISAEIQDELS
RTDYEQKR---FDQKNQ--RTKKGQ-N----MAKDIRTNTQDKT----VNKSVIPRKHSQ
KQIEEHFRNLPVR--GMPASSLQK-ERKEGLLKATTVIQDEDYM-LQVYGKPVYQGHRST
LKKGPYLRFNSPSPKS-KPQRPKVIERVKGTKVKSIRTQTDSYATKPMKIDSKMKHSIPM
-LPHGD-QQYLFSPSREMPTFSGTLEGHLIPMAILLGQTQSNSDTMPPAGVIVSKPHPVT
VTTSIPP---SSRKVETGVKKPNIAVVEMKSEKKDPPQLTVQVLPSVDIDSISNGSTDVG
SPL-SSP---KEAS-LPPVQAWIKTPEIMKVDEEEVKFPGTNFDEIIDVIQEE-EKCDEI
PD-SESILEFNRSVKADSTKYNGPPFPPVASTFQP--TANILDKVIERKETLE--NSLIQ
WVEQEIMSRIISGLFPIQQ-QIAPNISVS-VSETSEPLTSDIVEGTSSGALQLFVDAGVP
VNSDVINHFVNEALAETIEVMLGDREAKKEGPVATGVSGDASANETYL-PARVCTPLATP
QPTPPCSPSS----PTKECVLVKTPDSSPCDSDQDMAFPVKEICAEK----GDDMLAIML
VKTPTVTPTTTPPPAV-AVFTP-TLSDISIDKLKVSSPELPKPWGDGDLPLEEENPNS-P
Q-----EELHPRAIV-MSVAKDEEPES-MDFPAQPPPPE-PVPFMPFPAGTKAPSPSQMP
GSDSSTPESTLS-VTVTETETLDKPISEGEILFSCGQKLAPK--ILEDV--GLYLTNLND
SLSSTLHDAVEMEDDPPSEGQVI-RMPHKKFHADAILSVLAKQNQESAVSQQAVCHS--E
DMENSVGELSEGQRPQLIA-AAENILMGHS-LYMQPP-VTHAQSLDQQCDAKPLSRQFDA
V-SGSIYEDSCASHGPMSLGELQLEPNSNLVLPTTLLT-LQENDVNLPVAAE--------
--------------------DFSQYQQK--RNQDVKQVEHK---PSQS-YLHVTDKSDIA
PSH-IKHV----NTQDMHVELN-EFVLCVGGKAM-PLSA--------SQMPPAKMSMTLP
SV-----N---------L--EDCSQ-----------SLSISTMQEDMESSGADTF-----
---------------

----------------------------MKGSEVS--------PEKKKRLKMPARRLQEV
VSPNQGNNLAFLNSEL------PC-IPPALP-ANKRLPVRMGTP-VNGTLPGSSDLPSAR
-NYQPLL-E----NPTASE---SDFSKDVTMQE--LPLDKAEDSSRKEA

PF15324 // ENSGT00390000012397_0_Domain_2 (170, 1649)

DDI--FISQYT
VGQKDALRMALKQKA---------------------------------------------
-----QS------MPVFKEVKVHLLEDAGTEKGAV-LQEARVSPSGIDSATSVAAATAAA
IATAAPLIKVQSDLEAKVNSVTELLNKLQETDKHLKRVAEQQTSIQNK-QEKLHCH----
-DHEKQMNVFMEQHIRHLEKLQQQQIDIQTHFISAALKTSTC---PPASMLPSRAVEKHS
IKP-EHLHLGNSVLSSHNTIASKQA---------------------TLRKIEDMEFDELK
SPLETPAPRRFAPVPVSRDGKIS----KRENLIEEKENMEKSDH------GGNVRLLEQI
LNNNDFSTRKSES-SNITSLSRSKIGWNPERKDSFETLSSR-RFPSSE----ELRMAKVT
MQNPNDVLHDLGKKEKETNGTLQ-------------------------------------
--------------------------------NSG-KLQPTNTVRSVLKDAEKILRGVQN
NKKVLEENLEAIIRAKDGAAMYSFINALSTNREMSEKIRIRKTVDEWIKAISTEIQDEMA
RKDYEQRR---FDQKNQ--RTKKAQ-N----ISKDIKANTQDKT----VNKSVIPRK-PQ
KQVEDYLRRLPIR--NMATSSVQK-ERK-GLLKSPTVIQDEDYM-SQVYGKPVYQGHRST
LKRGPYLRFNSTSLNS-KPQRPKIIEQVKGTKVKSIRTQTDFHGIKPMKIDSRMQYPVTA
-LPRGE-QQYLFSPSREMPTFSGTLEGHLIPMAILLGQTQSNSDSVLPAGVIVHKPHPVT
VTTSIPP---SSGKVETGVKKPNVAVVEMKSEQKDPPRLTVQVLPRVDIDSISNDSADGG
SP-LPSP---RGAR-RSPPRMCTQTPEFMNVDEEEVKFPGTNFDEVIDVVQEE-EKCDEI
PECSEPILEFNRSIKVASTKYNGPPFPPVVCTSQP--TTDILDKVIERKETLE--NNLIQ
WVEQEIMSRIISGRFPVPQ-QTRLTTSVS-VSEASEPSTPDLVEGTCGGALQLFVDAGVP
VNSDTIRHLVNEALAETIAGMLGDRESKKQGHGATSVSGDISTSETPL-LARICTPVATP
QPTPPHSPAS----PPKEYVLVKTPDSSPCGSYHDVAFPVKEISAEKEKSSENDVPAITL
INTPTVTPATTPPLA--AALTP-TLSEISIDKLKISSPELPTPWGDRDLPLDEENPYC-L
QE----D-FHPRAIV-MSVAEDEEPES-MNFLPPPAPTE-PVPPTPFPAGTKAPSSSQMP
SSSSSTLESTLS-VTVTDMESLDRPISEGEIVFNCGERLAPR--ILGGG--ELYLTNLND
SLSSTLHDALDMEDDSPSEGQVI-RIPHKKFHADSILPLLARQNQELLVSQQAVCCS--E
DLENSVGELSEGQRPRLTA-AAENILLGQS-LYMQQC-VANAESMGQQCHPKPLFQQFDT
V-SGGIHEDPCASHGPMSLGELELQPRSNVVLPTALLR-TQGSDVYLPEAAE--------
--------------------DFSQNQQK--QDQDVKQVEHK---PVQSHLIRVRNISDIL
LSQQQQASP--GNMDQTQIEPS-LCLASVFTGGVAVPNFTSQRSP--------ARMSVTL
PAVNLEDCSPSLSV--------------------------STIQGDPGSSGADTF-----
---------------