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Query Results 

"ENSGT00390000012228_0"


Found:

ENSGT00390000012228_0


ENSMMUP00000009253 (view gene)
-MAALEESFPRGGTRK--IHKPEKAFQQSVEQDNLFDIS---TEEGSTKRK-KSQKGPAK
T----KKLKIEKRESSKSAREKFEILSVESLCEGMRILGCVKEVNELELVISLPNGLQGF
VQVTEICDAYTKKLNEQVTQEQPLKDLLHLPELFSPGMLVRCVVSSLGITDRGKKSVKLS
LNPKNVNRVLSAEALKPGMLLTGTVSSLEDHGYLVDIGVDGTRAFLPLLKAQEYIRQKNK
GAKLKVGQYLNCIIEKVKGSGGVVSLSVGHSEVSTAIATEEQSWTLNNLLPGLVVKAQVQ
KVTPFGLTLNFLTFFTGVVDFMHLDPKKAGTYFSNQAVRACILCVHPRTRVVRLSLRPIF
LQPGRPLTRLSCQNLGAVLDDVPVQGFFKKAGATFRLKDGVLAYARL------SHLSDSK
NVFNPEAFKPGNTHKCRIIDYSQMDELALLSLRTSIIEAQYLRYHDIEPGAVVKGIVLTI
KSYGMLVKVGEQMRGLVPPMHLADILMKNPEKKYHIGDEVKCRVLLCDPEAKKLMMTLKK
TLVESKLPVITCYADAKPGLQTH
PF00575 // ENSGT00390000012228_0_Domain_3 (564, 628)
GFIIRVKDYGCIVKFYNNVQGLVPKHELST-EYIPDP
ERVFYTGQVVKVAVLNCEPSKERMLLS
ENSGT00390000012228_0_Linker_3_4 (628, 759)
FKLSSDPEPKKE--PAGHSQKKGKAINIGQLVD
VKVLEKTKDGLEVAVLPH--NIRAFLPTSHLSDHVANGPLLHHWLQAGDILHRVL---CL
SQSEGHVLLCRKPALVSTVEGGQDPKNFSEIHPGMLLI
PF00575 // ENSGT00390000012228_0_Domain_4 (759, 823)
GFVKSIKDYGVFIQFPSGLSGL
APKAIMSDKFVTSTSDHFVEGQTVAAKVTNVDEEKQRMLLSL
ENSGT00390000012228_0_Linker_4_5 (823, 1077)
RLSDCALGDLATTSLLLL
SQCLEELQGVRSLMS--NR-DSVLIQTLAEMTPGMFLDLVVQEVLEDGSVVFSGGPVPDL
-VLRASRYHRAGQEVESGQKKKVVILNVDLLKLEVHVSLHQDLVNRK-AKKLRKGSEHQA
IVQHLEKSFAIASLVE--TGHLAAFSLTSHLNDTFRFDSEKLQVGQGVSLTLKTTEPGVT
GLLLAVEGPAAKRTMRPTRKDSETVDEDE-----------EVDPALTVGTVKKHTL
PF00575 // ENSGT00390000012228_0_Domain_5 (1077, 1139)
SIGD
MVTGTVKSIKPTHVVVTLEDGIIGCIHASHILDDVPEGISPTTKLKVGKTVTARVIGGRD
MKTFKFLPISHPRFVRTIPELSVRPSELE------DGHTALNTHSVSPVEKIKQYQAGQT
VTCFLKKYNVVKKWLEVEIAPDIRGRIPLLLTSLSFKVLKHPDK-KFRVGQA-LRATVIG
PD-SSKAFLCLSL-IGPHKLEEGEVAMGRVVKVTPNEGLTVSFPFGKIGTVSIFHVSDSY
SETPLEDFVPQKVVRCYILSTADSVLTLS---LRSSRTNPETKSKVEDPEINSIQDIKEG
QLLRGYVGSIQ-PHGVFFRLGPSVVGLARYSHVSQHSSSKKALYNKHLPEGKLLTARVLR
----------------LNHQKNLVELSFLPGDTGKPDLLSASLEGPLPKQEERKTEAEER
DQKGEKKNQKRN-----K-K-KNQKGQEE--VELPSK---------EKQQPQKPQAQ--K
RGGRERRESG------SEQERVSKKPKKAGPSEED----DSLMDVYYREGKEE-AEETNV
------------------------------LPKEKQTKPAEVPRLQLSSGFAWNVGLDSL
TP-ALPPLAESSDSEEDE-KPHQAMK--KKSKKERELEKQKAEKELSRIEEALMDPGRQP
ESADDFDRLVLSSPNSSILWLQYMAFHLQATEIEKARAVAERALKTISFRE-EQEKLNVW
VALLNLENMYGSQESLTKVFERAVQYNEPLKVFLHLADIYAKSEKFQEAGELYNRMLKRF
RQEKA
PF05843 // ENSGT00390000012228_0_Domain_7 (1866, 2008)
VWIKYGAFLLRRSQAGASHRVLQRALECLPSKEHVDVIAKFAQLEFQLGDAERAK
AIFENTLSTYPKRTDVWSVYIDMTIKHGSQKAV-RDIFERVIHLSLAPKRMKFFFKRYLD
YEKQHGTEKDVQAVKAKALEYVEAKSSVLED--
ENSDORP00000020336 (view gene)
-MATLEESFPRGGTRK--THKPEKSFQQSVEQDNLFDIS---TKEESTKRK-KIQKEKTK
T----KRLKIEKRESNKSKKEKFEILSVESLCEGMRILGCVKEVNELELVVSLPNGLQGF
VQVTEICDAYNKKLNEQVAQEEPLQDLLPLTELFSPGMLVRCVVRSVNITESGKKSVKLS
LNPKNVNRVLSAEAL
PF00575 // ENSGT00390000012228_0_Domain_0 (196, 268)
KPGMLLTGTVSSLEDHGYLVDIGVGGTRAFLPLPKAQDYIRQKNK
GAKLKLGQYLTCIVDEVKSNGGVVSLS
ENSGT00390000012228_0_Linker_0_1 (268, 468)
IGHSEISTALATEEQNWTLSNLLPGLVVKAQVQ
KVTPFGLKLNFLTFFTGVVDFMHLEPKKVGTYISKQTVRACILCVHPRTRIVRLSLRPIF
LQPGRPLTRLSYQHLGAVLDDVPVQGFFNKAGATFTLKDGALAYARL------SHLSDSK
KVFNPDAFKPGNTHKCRIIDYSQMDELALLSLKTSIIKAQYLRYHDI
PF00575 // ENSGT00390000012228_0_Domain_1 (468, 539)
KTGAVVKGTVLTI
KPFGMLVKIGEQIKGLVPTMHLADILMKNPEKKYHIGDEVKCRVLLCDPEAKKLIMTLKK
TLIMSKLPIITSYNDAKPGLQTHGVILRARDYGCIVKFYNDVQGLVPKPELCA-QYIPDP
EKVFFTGQVVKVAVLNCEPSKERMLLSFKLLSEPEPENE--SVGHSQKKKRAVNIGQLVD
VKVLEKTKDGLEVAVLPH--NIPAFLPTPHLSDHVTNGPLLYHWLQAGDTLHRVL---CL
SQSEKHLLLCRKPSLVSTVEGGQDPKSFSEIQP
PF00575 // ENSGT00390000012228_0_Domain_4 (754, 823)
GMLLIGFVRSIMDYGVFVQFPSGLSGL
APKALMSDKFVTTTSDHFVEGQTVVAKVTNVDEEKQRMLLSL
ENSGT00390000012228_0_Linker_4_5 (823, 1077)
RLSDCTLGKLASTSLLLL
SQCLEELQGVRSLMS--NR-DSVLIQTLAEMTPGMVLDLVVQEVLEDGSVVFSGGPVPDL
-VVRASRYHRTGQEVEPGQKKKVVVLSVDMLNLEVHVSLSQHLVNRK-TKRLKKGNRYQG
IVQHLEESFAVASLVE--TGQLAAFSLTSHLNDTFRFDSEKLQVGQGVCLTLKTTEPGVT
GLLLAVEGPAAKRTMTQIQKNLEAVDEEEE----------DDDPALTIGTKKKHSL
PF00575 // ENSGT00390000012228_0_Domain_5 (1077, 1142)
AIGD
IVTGTIKSIKATHVVVTLEDDIIGCIHASNILDDVPVGSSPTTKLKVGKTVTARVIGGRD
VKTSKFLPVSHPRFIRTVLELSVRPSDLE-----KDGHTALDTYTVSPMEKIKQFQAGQT
VTCFLKKFNVVKKWLEVEIAPDIRGRIPLLLTSLSFKVLKHPDK-NFRIGQA-LKAMVVS
SN-SSKTFLCLSL-IGPHKLKRGEVAMGQVVTVIPNEGLTVSFPSGKMGRVSIFHVSDSY
SEAPLEEFIPQKVVRCYVLSTEDKELTLS---LRSSRTNPETKNKIEDPEINSIQDIKEG
QLLRGYVKSIQ-PNGVLLGLGPSVEGLAQYSHVSRCSQPRKDLYSKYLPEGKLLTARILS
----------------LNHQKNLVELSFLPSDTGKPDVFSASPEPPLVNQKKDQKEEEEK
KKKK---------------VKKSQKGKEE-KKELQR-------------------PQ-KS
QGKRERQQSE------SEQEGVNKRLKKAGTLEED----KSSVEVYYREEEEE-IEVPKL
------------------------------LPKGRQTNSTEVPRLQLSSGFVWDVGLDSL
TP-ALPPREESSDSEEEE-KPHQATK--KKSKKERELEKQKAEKDLCRIEEALMDPGRQP
ESADDFDRLVLSSPNSSILWLQYMAFHLQATEIEKARAVAERALKTISFRE-EQEKLNVW
VALLNLENMYGSEESLTKVFERAVQYNEPLKVFLHLADIYTKSEKFKEAGDLYNRMLKRF
RQDK
PF05843 // ENSGT00390000012228_0_Domain_7 (1865, 2008)
VVWIKYGAFVLRRHQAGASHRVLQRALECLPTKEHVDVIAKFAQLEFQLGDAERAK
AIFENMLSTYPKRTDVWSVYIDMVIKHGSQKEV-RDIFQRVIHLSLAPKRMKFFFKRYLD
YEKQYGTEKDVQAVKAKALEYVEAKSSVLED--
ENSNGAP00000017903 (view gene)
-MAALEESFPRGGSRK--THKSEKSSQQPVEHDNLFDVS---PEEKSNKRK-NSQKGPAK
T----KKLKIEKRET-KSVKEKFEILSVKSLCEGMRILGCVKEVNDLELVISLPNGLQGF
VQVTEICDAYTQKLNEQVAQEDPLKDLLRLPELFSPGMLVRCVVSSLGITESGKKNVKLS
VNPKHVNKVLDAEAL
PF00575 // ENSGT00390000012228_0_Domain_0 (196, 268)
KPGMLLTGTVSSLEDHGFLVDIGVSGTRAFLPLQKAQEYIRQKNK
GAKLKVGQYLTCLIEEVKSNGGVVVLS
ENSGT00390000012228_0_Linker_0_1 (268, 468)
VGQSEISSAFATEEQSWNLNNLLPGLVIKAQVQ
KVTPFGLTLNFLTFFTGLVDFMHLDPKKIGTYSSKQTVRACVLCIHPRTRVVRLSLRPVF
LQPGRPLTRFSYQRLGAVLDNVPVQGFFNKAGATFRLKDGVLAYARL------SHLSDSK
KSCSADAFKPGSTHKCRIIDYSQMDELALLSLRKSVIEAQFLRYHDI
PF00575 // ENSGT00390000012228_0_Domain_1 (468, 539)
KIGAVVKGTVLTI
KPFGMLVKVGEQMRGLIPPMHLADILMKNPEKKYHIGDEVKCRVLLCDPEAKKLVMTLKK
TLVTSKLPAITCYEDAKPGLQTHGVIFRVKEYGCIVKFYSDVQGLVPKHELSA-QYIPDP
EKVFYPGQVVKVAVLNCEPSKERMLLSFKLLSDPETKNE--SASNGQKKGRAVNIGQLVD
VKVLEKTKDGLEVAILPH--NIPAFLPIPHLSDHVANGPLLHHWLQAGDTLHRVL---CL
SRSEKHVLLCRKPALVSTVEGGQDPKSFSEIQP
PF00575 // ENSGT00390000012228_0_Domain_4 (754, 823)
GMLLIGFVKSVKDYGVFVQFPSGLSGL
APKTIMSDKFVTTPSDHFVEGQTVVAKVTNVDEEKQRMLLSL
ENSGT00390000012228_0_Linker_4_5 (823, 1077)
RLSDCSLGESASTSLLLL
SQCLEELQGVRSLMS--NQ-DSVLFQTLAEMTPGMVLDLMVQEVLEDGSLVFSGGPVPDL
-MVRASRYHQAGQEVECGQKRKVVILNVDMLKLEVHVSLRQDLVNRK-TRKLKKGSEHQA
IVQHLEKSFAVASLVE--TGHLVAFSLTSHLNDTFRFDSEKLYVGQGVYLTLKTTEPGVT
GLLLAVEGSAAKRTRRHARRDSETVDDNEE---------E-EDPALAVGSKKKHTL
PF00575 // ENSGT00390000012228_0_Domain_5 (1077, 1142)
AIGD
KVTGTIKSVKATHVVVTLEDGIIGCIHASRILDDVPLGISPTATLKVGKTVTARVIGGRD
VKTSKFLPVSHPRFVQTILELSVRPNELE-----KDDHSALNTCSESPVEKIKQYHVGQT
VTCFLKRYNVVKKWLEVDIAPDIRGRIPLLLSSLSFKVLKHPDK-KFQIGQA-LRATVVG
PD-SCKAFLCLSL-IGPYKLEPGDVAMGRVVKVIPNEGLTISFPFGKLGKVSIFHVSDSY
TETPLEDFIPQKVVRCYVLSTADHMLVLS---LRSSRTNPETKSRIRDPEVNCIQDVKEG
QLLRGYVKSVQ-QNGVLVGLGPSVVGLAQHSHVSQCSPPKKELFNKYLPEGKLITTKILS
----------------VNHQKNLVELSFLPCDTGKPDVFSASPELPLLKQEERRPEAKGK
DLKE---KKKSQK---R--KEKNQKGQE--ELQLSSQ---------EKKEPQKPQGK--R
QGKRERQESG------SEQERMNKKPKKAGAPEED----DSGVEVYYREGEEE-MEELKV
------------------------------LPKGGQMKPTEVPRLQLSSGFTWDVGLDSL
TP-ALPTRGESSDSEED-EKPRQATK--KKSKKERELEKQKAEKELSRIEEALMDPGRQP
ESADDFDRLVLSSPNSSILWLQYMAFHLQATEIEKARAVAERALKTISFRE-EQEKLNVW
VALLNLENMYGSQESLTKVFEQAVQYNEPLKVFLHLADIYTKSEKFKEAGELYNRMLKRF
RQEKAVWIKYGAFVLGRSQAGASHRVLQRALECLPTK
PF05843 // ENSGT00390000012228_0_Domain_7 (1898, 2008)
EHVDVIAKFAQLEFKLGDAERAK
AIFENMLSTYPKRTDVWSVYIDMTIKHGSQKEV-RGIFERVIHLSLAPKRMKFFFKRYLD
YEKQHGTEQDVQAVKAKALEYVEAKSSVLED--
ENSGGOP00000011353 (view gene)
-MANLEESFPRGGTRK--IHKPEKAFQQSVEQDNLFDIS---TEEGSTKRK-KSQKGPAK
T----KKLKIEKRESSKSAREKFEILSVESLCEGMRILGCVKEVNELELVISLPNGLQGF
VQVTEICDAYTKKLNEQVTQEQPLKDLLHLPELFSPGMLVRCVVSSLGITDRGKKSVKLS
LNPKNVNRVLSAEALKPGMLLTGTVSSLEDHGYLVDIGVDGTRAFLPLLKAQEYIRQKNK
GAKLKVGQYLNCIVEKVKGNGGVVSLSVGHSEVSTAIATEQQSWNLNNLLPGLVVKAQVQ
KVTPFGLTLNFLTFFTGVVDFMHLDPKKAGTYFSNQAVRACILCVHPRTRVVRLSLRPIF
LQPGRPLTRLSCQNLGAVLDDVPVQGFFKKAGATFRLKDGVLAYARL------SHLSDSK
NVFNPEAFKPGNTHKCRIIDYSQMDELALLSLRTSIIEAQYLRYHDI
PF00575 // ENSGT00390000012228_0_Domain_1 (468, 538)
EPGAVVKGTVLTI
KSYGMLVKVGEQMRGLVPPMHLADILMKNPEKKYHIGDEVKCRVLLCDPEAKKLMMTLKK
TLIESKLPVITCYADAKPGLQTHGFIIRVKDYGCIVKFYNNVQGLVPKHELST-EYIPDP
ERVFYTGQVVKVVVLNCEPSKERMLLSFKLSSDPEPKKE--PAGHSQKKGKAINIGQLVD
VKVLEKTKDGLEVAVLPH--NIRAFLPTSHLSDHVANGPLLHHWLQAGDILHRVL---CL
SQSEGRVLLCRKPALVSTVEGGQDPKNFSEIH
PF00575 // ENSGT00390000012228_0_Domain_4 (753, 823)
AGMLLTGFVKSIKDYGVFIQFPSGLSGL
APKAIMSDKFVTSTSDHFVEGQTVAAKVTNVDEEKQRMLLSL
ENSGT00390000012228_0_Linker_4_5 (823, 1077)
RLSDCGLGDLAITSLLLL
NQCLEELQGVRSLMS--NR-DSVLIQTLAKMTPGMFLDLVVQEVLEDGSVVFSGGPVPDL
-VLKASRYHRAGQKVESGQKKKVVILNVDLLKLEVHVSLHQDLVNRK-ARKLRKGSEHQA
IVQHLEKSFAIASLVE--TGHLAAFSLTSHLNDTFRFDSEKLQVGQGVSLTLKTTEPGVT
GLLLAVEGPAAKRTMRPTRKDSETVDEDE-----------EVDPALTVGTIKKHTL
PF00575 // ENSGT00390000012228_0_Domain_5 (1077, 1139)
SIGD
MVTGTVKSIKPTHVVVTLEDGIIGCIHASHILDDVPEGTSATTKLKVGKMVTARVIGGRD
MKTFKYLPISHPRFVRTIPELSVRPSELE------DGHTALNTHSVSPVEKIKQYQAGQT
VTCFLKKYNVVKKWLEVEIAPDIRGRIPLLLTSLSFKVLKHPDK-KFRVGQA-LRATVVG
PD-SSKTFLCLSL-TGPHKLEEGEVAMGRVVKVTPNEGLTVSFPFGKIGTVSIFHMSDSY
SETPLEDFVPQKVVRCYVLSTADNVLTLS---LRSSRTNPETKSKVEDPEINSIQDIKEG
QLLRGYVGSIR-PHGVFFRLGPSVVGLARYSHVSQHSPSKKALYNKHLPEGKLLTARVLR
----------------LNHQKNLVELSFLPGDTGKPDVLSASLEGPLTKQEEGKTEAEER
DQKGEKKNQKRN-----E-K-KNQKGQEE--VEMPSK---------EKQQPQKPQAQ--K
RGGRECRESG------SEQERVSKKPKKASLSEED----DSLVDVYYREGKEE-AEETNV
------------------------------LSKEKQTKPAEAPRLQLSSGFAWNVGLDSL
TP-ALPPLAESSDSEEDE-KPHQAMK--KKSKKERELEKQKAEKELSRIEEALMDPGRQP
ESADDFDRLVLSSPNSSILWLQYMAFHLQATEIEKARAVAERALKTISFRE-EQEKLNVW
VALLNLENMYGSQESLTKVFERAVQYNEPLKVFLHLADIYAKSEKFQEAGELYNRMLKRF
RQEKA
PF05843 // ENSGT00390000012228_0_Domain_7 (1866, 2008)
VWIKYGAFLLRRSQAAASHRVLQRALECLPSKEHVDVIAKFAQLEFQLGDAERAK
AIFENTLSTYPKRTDVWSVYIDMTIKHGSQKDV-RGIFERVIHLSLAPKRMKFFFKRYLD
YEKQHGTEKDVQAVKAKALEYVEAKSSVLED--
ENSMLUP00000004568 (view gene)
-IATMEESFPRGGTRKTHKSE--IAPQQSVEQDNLFDVS---TEEESIKRK-KSQKGPAK
T----KKLKIEKRESSKSIEEKFEILSIESLYEGMRILGCVKEVNELELVISLPNGLQGF
VQVTEISDAYTKKLNEQVEQEEPLKDLASLPELFSPGMLVRCVVSSLGITEKGKKSVKLS
LNPQNVNKVLSAE
PF00575 // ENSGT00390000012228_0_Domain_0 (194, 269)
ALKPGMLLTGTVSSLEDHGYLVDIGVGGARAFLPLQKAQEYIRQKNK
GAKLKVGQYLHCVIKEVKGNGGVVSLSIGHSEVSTAIATEEQSWTLNNLLPGLVVKAQVQ
KVTPLGLTLNFLSFFTGLVDFMHLEPKKAGTYFSNQAVRACVLCVHPRTRAVRLSLRPVF
LQPGRPLTQLSCQHLGAVLDDVPVQGFFSKAGATFSLKDGSLAYARL------SHLSDSK
KTFNPEAFKPGNTHKCRIINYSQMDELALLSLRTSIIEAQFLGYHDIKPGALVKGTVLTI
KPYGMLVKVSEQIRGLVPPMHLADIPMKNPEKKYHIGDEVTCRVLLCDPEAKKLMMTLKK
TLVESKLPAITCYD
PF00575 // ENSGT00390000012228_0_Domain_3 (555, 629)
DTKPGLQTHGFILRVKDYGCIVKFYNDVQGLVPKHELSA-EYVPDP
ERVFYTGQVVKVAVLNCEPSKERMLLSF
ENSGT00390000012228_0_Linker_3_4 (629, 750)
RLLTDPK--KE--HVGQSQKKRKAVNVGQLVD
VKVLEKTKDGLEVTVLPH--NIPAFLPTSHLSDHVANGPLLHHWLQAGDTLHRVL---CL
SQSEGHVLLCRKPALVSTVEGGQDPKTFS
PF00575 // ENSGT00390000012228_0_Domain_4 (750, 823)
EIHPGMLLIGFVKSIKDYGVFVQFPSGLSGL
APKAIMSDKFVTSTSDHFVEGQTVVAKVTNVDEEKQRMLLSL
ENSGT00390000012228_0_Linker_4_5 (823, 1075)
RLSDCTLGDLATTSLLLL
SQCLEERQGVRSLMS--NR-DSVLIQTLAEMTPGMVLDLEVQEVLEDGSVVFSEGPVPGL
-VLRASKYHQAGQEVESGQKKKVVILNVDMLKLEVHVSLCHDLVNRK-AKKLKKGSEHQA
IVQHLEESFAVASLVE--TGHLAAFSLTSHLNDTFRFDSEKLQVGQGVSLTLKTTEPGVT
GLLLAVEGPAAKRTMRQTRKDSETVDEDD-----------EGDPSMVVGTKKKH
PF00575 // ENSGT00390000012228_0_Domain_5 (1075, 1150)
TLSIGD
MVTGTVKSIKPTHVVVTLENGIIGCIHASHILDDVPEGTSPTARLKVGKKVTARVIGGRD
VKTSKFLPISHPRFIRTIPELSVRPSVLE-----KDGHAALNTHSVSPLEKIKQFQAGQT
VTCFLKKYNVIKKWLEVEIAPDIRGRIPMLLISLSFKVLKHPDK-KFQIGQA-LKATVVG
PD-SSKAFLCLSL-IGPHKLEKGEVAMGRVVKVTPNKELTVSFPFGRIGRVSIFHVSDSY
SEAPLEDFTPEKIVRCYVLSTADEVLTLS---LRSSRTNPETKSKVPDPEINSIQDVQEG
QLLRGYVKSVQ-PHGVLLGLGPSVVGLAQYPRVSQHSPSEKALYERYLPEGKLLTAKVLS
----------------VNHQKNLVELSFLPSDTGKPDVFPASPGLSPLKQGEKQVEVEER
DHKGKEEK-EKKKKNQKRKEKRNQKGQE--EAQLPSK---------EKKEPQKPHAE--K
QGKRPHRESA------SEQERANKKQKKAAPAEED----DSGVEVYYREGEEE-MEEISV
------------------------------LPKGKQTRPAEVPRLQLSSGFVWDVGLESL
TP-ALPPRRESSDSEEDE-KPQQTT-KK-KSKKERELEKQKAEKELSRMEEALMDPGRQP
ESADDFDRLVLSSPNSSILWLQYMAFHLQATEIEKARAVAERALKTISFRE-EQEKLNVW
VALLNLENMYGSQESLTKVFERAVQYNEPLKVFLQLADIYTKSEKFQEAGELYNRMLKRF
RQEKAVWVKYGAFLLRRGQAGASHRVMQRALECLPQKEHVDVISKFAQLEFQLGDAERAK
AIFENTLSTYPKRTDVWSVYIDMTIKHGSQKEV-RDIFERVIHLSLAPKRMKFFFKRYLD
YEKQHGTEKDVQAVKAKALDYVEAKSSVLED--
ENSGALP00000045223 (view gene)
------------------------------------------------------------
----------------------------------MLFLGCIKEVTVFELVISLPNGLTGF
VPVTHISDAYSELLSKQVTQGELLEDLNSLSDLYSPGMLVRCVVTSVEKSADGRRSIKLS
INPKSVNKGLSASALT
PF00575 // ENSGT00390000012228_0_Domain_0 (197, 267)
SGMLLSGFVSSVEDHGYLIDIGVSGTHAFLPHQKAQNYIKAVKR
GSDLKIGQSLNCVIEEVKNEGRVVRLSADRSEVAASIATEQQNWTLSNLLPGLVVKAQVQ
KVAPLGVSLTFLSSFTGIVDFMHVDPEKSTNYSPNQMVRRISLTGP--------------
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ENSOCUP00000005468 (view gene)
-MATLEESFPRGGTRKKSDHKSEKSFPQSVEQDNLFDIS---TEEESTKRK-KSQKGPAK
T----KKLKSEERERSKSVREKFEILSVESLCEGMRILGCVKEVNELELVISLPNGLQGF
VQVTEICDAYTEKLNEQMTQEEPLKDLLRLPELFAPGMLVRCVVRSLAITEKGKRSVKLS
LNPKNVNKVLSAEAL
PF00575 // ENSGT00390000012228_0_Domain_0 (196, 268)
KPGMLLTGTVSSLEDHGYLVDIGVGGTRAFLPLQKAQEYIRQKNK
GANLKVGQYLHCIIEEVKGDGGVVSLSVGHAEVSAAIASEEQSWTLNNLLPGLVVKAQVQ
KVTRFGLTLNFLKFFTGLVDFMHLDPKKVGTYFSNQAVRACILCVHPRTKVVRLSLRPIF
LQPGRPLTRLSCQHLGAVLDDVPVQGFFIKAGATFSLKNGVLAYARL------SHLSDSK
KVFKPEAFKPGNTHKCRIIDYSPLDELVLLSLRTSIIEAQYFRYHDIKPGAVIKGTVLTI
KPYGILLKVGERIRGLVPPSHLADILMKNPEKKYHIGEELKCRVLLCDPEAKKLIMTLKK
TLVESKLPPITCYADAQPGLQT
PF00575 // ENSGT00390000012228_0_Domain_3 (563, 628)
HGVIIRVKDYGCIVKFYNDVQGLVPKHELSA-QYIPDP
GSVFYTGQVVKVVVLNSEPSKERMLLS
ENSGT00390000012228_0_Linker_3_4 (628, 753)
FKLLSDGEPKKE--HAGQGQKKGRGVTVGQLVD
VKVLEKTKDGLEVAVLPH--NIPAFLPTSHLSDHVANGPLLYHWLQAGDILHRVL---CL
SQSEKHLFLCRKPALVSTVEGDQDPKNFSEIH
PF00575 // ENSGT00390000012228_0_Domain_4 (753, 823)
PGMLLIGFVKSIKDYGVFVQFPSGLSGL
APKAIMSDKFVTSPSDHFVEGQTVVAKVTNVDEEKQRMLLSL
ENSGT00390000012228_0_Linker_4_5 (823, 1078)
RLSDCMLGDVASTSLLLL
SQCLEELQGVRSLMS--NR-DSVLIQTLAKMTPGMVLDLMVQEVLEDGCVLFSGGPVPGL
-VLKASKYHRAGQEVESGQKKKVVILNVDMLKLEVHVSLLQNLVDRK-AKKLKKGSEHQA
IVQHLEESFAVASLVE--TGHLAAFSLTSHLNDTFRFDSEKLQVGQGVSLTLKTTEPGVT
GFLLAVEGPVAKRTMRQTRKDSEAVDEDE-----------EVDPALAVGPIKKHALS
PF00575 // ENSGT00390000012228_0_Domain_5 (1078, 1139)
IGD
KVTGTVKSVKPTHVVVTLEDGITGCIHASQILDDVPVGTSPTAKLKVGKTVTARVIGGRD
VKTFKFLPISHPRFIRTIPELSVRPSELE-----KDGHTALNTYSVSPVEKIRQYQAGQT
VTCFLKKYNVVKKWLEVEIAPDIRGRIPLLLTSLSFKVLKCPDK-KFRVGQA-LKATVVG
PV-SSKAFLCLSL-IGPHKLEKGEVAMGRVVEVTPNKGLTVSFPFGKKGRVSIFHVSDSY
SETPLQDFVPQKIVRCYVLSTEEQMLTLS---LRSSRTNPETKSKVEDPEIDSIQDVKEG
QLLRGYVRSVQ-PNGVLFSLGPSVTGLADYPHVSQYSPSEKDLYNKYLPEGKLLTAKVLR
----------------LNHRQDLVELSFLPCDTGKPDVFPASLELPLLKQGERKREAKEK
SQKGEGKEKNSQK---MK-Q-KKSKGQE--EVQLPSK---------EKREPQLPPGK--R
QGKRARRESG------SEQEREDKKPRKAGPPEED----DSGVEVYYREGEEE-IEEVDV
------------------------------LPK-KLTRPAEAPRLQLSSGFVWNVGLDSL
TP-ALPPRGESSDSEEDE-KPHPATK--KKSKKERELEKQKAEKELSRIEAALMDPGRQP
ESADEFDRLVLSSANSSILWLQYMAFHLQATEIEKARAVAERALKTISFRE-EQEKLNVW
VALLNLENMYGSQESLGKVFERAVQYNEPLKVFLHLADIYTKSEKFQEAAELYNRMLKRF
RQEKA
PF05843 // ENSGT00390000012228_0_Domain_7 (1866, 2007)
VWIKYGAFLLRRSQAGASHRVLQRALECLPAKEHMDVIVKFAQLEFQLGDAERAK
AIFENTLSTYPKRTDVWSVYIDMTIKHGSQKEV-RDIFERVIHLSLAPKRMKFFFKRYLD
YEKQHGTEKDVQAVKAKALEYVEARSSVLED--
ENSCGRP00000004876 (view gene)
-MANLEESFPRGGTRK--SHKLEKSFQQAVEQDNLFDIS---TEEESTKRK-KTQKGPIK
A----KKLKLEKKEVSKSVREKFEILSVESLCEGMRILGCVKEVNELELVISLPNGLQGF
VQVTEICDAYTQKLNEQVTQEEPLEDLLRLPDLFSPGMLVRCVVSSLDITERGKKSVKLS
VNPKHVNKVLSAEALRPRMLLTGTVSSLEDHGYLVDIGVSGTRAFLSLHKAQEYIRQKNK
GANLKIGQYLTCLVDEVKSNGAVVGLSIEHSEISSAFATEEQSWNLNNLLPGLVVKAQVQ
KVTEFGLQLNFLTFFTGLVDFMHLEPKKIGAYSSKQTVKACILCIHPRTRVVRLSLRPVF
LQPGRPLTRISYQQLGAVLDKVPVQGFFKKAGATFRLKDGALAYARL------SHLSDSK
KTFNPEAFKPGSTHKCRIIDYSQMDELALLSLRKSIITAQFLSYHDI
PF00575 // ENSGT00390000012228_0_Domain_1 (468, 539)
KTGTVVKGTVLAI
KPFGILVKVGEQMRGLVPSMHLGDIMMKNPEKKYHLGDEVKCRVLLCDPEAKKLIMTLKK
TLITSKLPAIMCYEDAKPGLQTHGVIIRVKSYGCIVKFYNSVQGLVPKHELSD-QHIPDP
EKVFYTGQVVKVAVLNSEPSKERLLLSFKLLSDSEPKND--SVEISQKKGRAVNIGQLVD
VKVLEKTKDGLEVAILPH--NTPAFLPTPHLSDHVANGPLLHHWLQAGDTLHRVL---CL
SQGEKHILLCRKPALVSTVEGGQDPKSLSEIQP
PF00575 // ENSGT00390000012228_0_Domain_4 (754, 823)
GMLLIGFVKSIKDYGVFVQFPSGLNGL
APKAIMSDKFVTTPSDHFVVGQTVVAKVTNVDEEKQRMLLSL
ENSGT00390000012228_0_Linker_4_5 (823, 1077)
RLSDCSLGDPASTSFILL
CQCLEELQGVRSLMS--NQ-DSVLMQTLAEMTPGMVLDVMVQEVLEDGSVVFSG-HVPDL
-ILKASRYHRAGQEVASGQKRRVVVLHVDMLKLEVHVSLRQDLVHRK-ARKLRKSSRHQG
IVQHLEESFAVASLME--TGQLVAFSLTSHLNDTFHFDSEKLHVGQGVCLTLKTTEPGVT
GLILAVEGPASKRTSTPARRDSETADDKEE---------EEENSDLTVRTKKKHGL
PF00575 // ENSGT00390000012228_0_Domain_5 (1077, 1139)
AIGD
KVTGTIKSVKATHVVVTLEDGIIGCIHASRILDDVPVGTSPTTTLKVGEKVTARVIGGRD
LKTSKFLPISHPRFVLTILELSIRPSELK-----KDGYSALNTHSESPLEKTEQYQAGQT
VTCFFKKYNAIKKWLEVDVAPDIRGRIPLLLTSLSFKVLKHPDK-MFQVGQA-LRATVVG
SD-VPKAFLCLSL-IGPYKLEQGEIAMGRVLSVVPNKGLTISFPFGKVGKVSLFHVSDSY
SEALLEDFFPQKIVRCYVLSTEHHVLTLS---LRSSRTNRETKSKVEDPEINSIQDVKEG
QLLRGYVKSVL-SHGVLVELGPSVVGLAQYSHVSQCRPPEKELYDSYLPKGKLVTAKVLR
----------------VNPERSQVELSLLPSDTGKPDLFSASPEPPLLNGEERKEGAKER
VRKGEEKKS--QK---R--KEKNQKGQE--EAELSSQ---------EKKE---SQRH--R
QGKRERHEPV------SEQERVNKRPKKSGTPEED----DSGVEVYYREGEDE-MEQPGV
------------------------------LPMGKQTKPAEVPRLQLSSGFVWDVGLDSL
TP-ALPPRGESSDSEED-EKPHQAKK--KKGKKERELEKQKAEKELSRIEEALMDPGRQP
ESADDFDRLGLSTPNSSILWLQYMAFHLQATEIEKARAVAERALKTISFRE-EQEKLNVW
VALLNLENMYGSQESLMKVFERAVQYNEPLKVFLHLADIYTKSEKFKEAGELYSRMLKRF
RQEKAVWIKYGAFVLGRSQAGTSHRVLQRALECLPTKEH
PF05843 // ENSGT00390000012228_0_Domain_7 (1900, 2008)
VDVISKFAQLEFQLGDAERAK
AIFENTLSTYPKRTDVWSVYIDMTIKHGSQKEV-RDIFERVIHLSLAPKRMKFFFKRYLD
YEKQHGTEKDVQAVKAKALEYVEAKSSVLED--
ENSOANP00000002619 (view gene)
-MASTDESFPRGGVKPKPDRE--KAVKQPLEQDNLFDFFKTHDEGRTQRRK-KSQNDPKR
K----KTRRSDKKEPKKSDAELFELLSVQNLSEGVLLLGCVKESNKYEMVISLPNGLRGF
VQATSISDTYTKKLAEQVEREEFLEDVMPLSALYLPGMLVRCVVNSIETTKKGKQSIRLS
LNPKEVNRGLSAGTLSPGMLLTGTVSSREDHGYLIDIGVRESKAFLPRKKAQEYISMRNK
GSELKLGQYLWCYVEEVKGNGSIVRLSIGSAEVASALATEEQNWTLDNVLPGLVVKAVIQ
KVTPHGLSLSFLSIYRGLVDFLHLDPKKSQSYFATQKVKACILSVHRQTKTVRLTLRPNF
LHPGLPLSQLSTSLVGTVLENVPVQGFFKKAGATFKLKDGSLAFARF------KHLSNSK
KSFNPEKFLPGKTHKCRIIDLSPMDDLVLLSLKEKIINAPFLQYRDLQPGQLVQGKVLAL
RPFGVLVEVTDSIKGVVPLLHLADVQLKHPEKKFHLGDEIKGRVLSCIPSMKKLVLTLKK
TLVNSDLPVITSYRAAKPQLQAH
PF00575 // ENSGT00390000012228_0_Domain_3 (564, 629)
GFISKITEVGCIVGFYNNVRGLVPKGRLGV-DCSEDL
KSVFYLGQVIKVTVVNCSPNQERLLLSY
ENSGT00390000012228_0_Linker_3_4 (629, 752)
KPMMDSEP-AG-----------SAEMLGQMVD
VKVVKKTDMGLQVSILPG--NVPAFLPKIHLSDHVSNSQLLWHWLQPNDILHRVL---CL
GSKRGRNILSRKPALICAAEEGQVARYFFDI
PF00575 // ENSGT00390000012228_0_Domain_4 (752, 823)
QPGMLFTGYVTSIMDYGVFVELPFGFTGL
SPRVAISDKFVTKTQDHYTVGQTVTALVTDVDEEKQRMLLSL
ENSGT00390000012228_0_Linker_4_5 (823, 1078)
RLSDCNLRDPATVGFSLL
CQCLEELQGVRLLMK--NQEDNTLIQFLASLTPGLRLNLIVQEVLEGGSVTFSGGLGPGL
-VLSASKYHVGGEKLEPLQRVKTVVLHVDTLKLKVHVSLRPELLNRK-FKKVKLNDQHMA
VVQHLEKEFVIASLVE--TGQLVAFPIASHFNDTFRFDSEKLQLGQGVCLTLRTTEPGDF
GLLLATKEPASKRVVPKPQEKLEPTGEPQEKVGPTR--KPQKKVGPTREAVKKHAFS
PF00575 // ENSGT00390000012228_0_Domain_5 (1078, 1140)
IGE
LVKGIVRSVKPTYIIVTLESGITGFIHVSQILDEVPLGTCPTTRLKAKKRITARVIGGKD
MRTRRFLPATHSRFIRTVPELSIRPSELK-----ASSTAL-NTHSYSHALKFRGYNVGKQ
VICFVKKYNIVEKCLEVEVSPVISGKVPHLLLSLSYKVLRHPEK-KFKVGQA-LSAIVVG
TDSSRS-LLILSL-TGIHKLKKGTITMGKVMKVIPDVGLTVRLPFECAGQVSIFHIQDSY
SAVPLEGFKPEKIVKCCVLSTKGTMMELS---LRLSRTKSNYQEKVEDREVTSLDDVKEG
ELLRGYVKSVE-HQGVFISISSTVVGQVQYQCVSQYLVSNQKLYNKYLRKGMLLTTKVLS
----------------VNKEQNLVELSLLPQDTGKQDVFPSSLKLPLHDEEKGKGKENLT
KEKK------ETLKD---------------------------------------------
--KRKRGELETK----QEETPRKKKKTQASEEDEE----DSGVEVYYREGKVDKE-AREK
P-------------------------------QKKQIKPAEAPRLQLSSAFAWDVGLDTL
TS-VVQPKEESSESEDEEQ-QQVTLK--KKTKKDKEAEKQKAEKELSRIEATLMDPSRQP
ETADDFDRLVLSSPNSSILWLQYMAFHLHATEIDKARAVAERALKIISFRE-EQEKFNVW
VALLNLENMYGSEESLTKVFERAVQYNDSLKVFLQLADIYAKSEKYTEAEELYGKMLKRF
RQEKSVWLKYSAFLLRRGQFEANHQLLHRALKCLPDKDHVDVISK
PF05843 // ENSGT00390000012228_0_Domain_7 (1906, 2006)
FAQLEFHLGDAERAK
AIFESTLSNYPKRTDIWSVYIDMTIKHGSQKEV-RDIFERVIHLSLAAKRMKFFFKRYLD
YEKQHGSPETVQAVKEKAVEYVEGQSSQLKG--
ENSOARP00000003976 (view gene)
-MAAMEESFPRGGTRKTHKSE--KAFQQSVEQDNLFDIS---TEEESTKRK-KTQKGPAK
T----KKVKVETRESSKFVREKFEILNVESLCEGMRILGCVKEVNELELVISLPNGLQGC
VQVTEICDAYTEKLNEQVAQEEPLQDLVGLPELFSPGMLVRCVVSSLDTTKWGKKNVMLS
LNPKNVNRVLSAETL
PF00575 // ENSGT00390000012228_0_Domain_0 (196, 268)
KPGMLLTGTVSSLEDHGYLVDIGVSGARAFLPLQKAQEYIRQKNK
GARLKVGQYLNCLIEEVKGSGGVVTLS
ENSGT00390000012228_0_Linker_0_1 (268, 468)
IGHSEVSAAIATEEQSWTLNSLLPGLVVKAQVQ
KVTPLGLTLKFLSFFSGLVDFMHLDPKRAGTYFSNQQVRACVLCVHPRTRAVRLSLRPIF
LQPGRPLTRLLCQQLGAVLDDVPVQGFFGNAGATFKLKDGALAYARR------NHLSNSK
KTFKPEAFKPGNTHKCRIIDYSQMDELALLSLRTSIIEAQFLWYHDI
PF00575 // ENSGT00390000012228_0_Domain_1 (468, 539)
KPGALVKGKVLTI
KPHGMVVKMGKQIRGLVPTMHLADILIKNPEKKYHVGDEVKCRVLLCDPKAKKLMMTLKK
TLVESKLPAITCYDDAKPGLQTHGFILRVKEYGCIVKFYNDVQGLVPRHELSA-EYVPDP
ESVFYTGQVVKVAVLNCEPSKERMLLSFRLLSDPK--QE--CEGQSQKKKKAVSAGQLVD
VKILEKTKDGLKVAVLPH--NIPGFLPTAHLSDHVTNGPLLYHWLQTGDTLHRVL---CL
SASEERVLLCRKPALVSAVEGGQNPKSFSEIH
PF00575 // ENSGT00390000012228_0_Domain_4 (753, 823)
PGMLLIGFVKNIKDYGVFIQFPSGLSGL
APKAILSDKFVTSTSDHFVEGQTVVAKVTNVDKEKQRMLLSL
ENSGT00390000012228_0_Linker_4_5 (823, 1078)
RLSDCTLGDLATTSLLLL
SQCLEERQGVRSLMS--NQ-DSVLIQTLAEMTPGMALDLEVQEVLEDGSVLFSEGPVPGL
-VLRASKYHRAGQELEPGQKKKAVILNVDMLKLEVHVSLCHDLVNRK-AKKLKKGSDLQA
IVQHLEESFAVASLVE--TGHLAAFSLTSHLNDTFRFDSEKLQVGQGVSLTLQTTEPGVT
GLLLAVEGPAAKRTMRQARKDSETVDEDE-----------EVDPALVIGTVKKHTLS
PF00575 // ENSGT00390000012228_0_Domain_5 (1078, 1138)
IGD
MVTGTVKSIKPTHVVVTLEDGIIGCIHASHILDDVPVGTSPTAKLKVGKKVTARVIGGRD
MKTFKFLPISHPRFIRTIPELSVRPSELK-----EDGHTALNTHSVSPLEKIKQYQAGQT
VTCFLKKYNMVKKWLEVEIAPDVRGRIPLLLTSLSFKVLKHPDK-KFQIGQA-LKATVVG
PADSSKAFLSLSL-IGPHKLKKGEVAMGRVVKVTPKEGLTVSFPFGRVGRVSMFHVSDSY
SETRLEDFAPQQIVRCYVLSAASPVLTLS---LRSSRTNPETKSKITDPEINSIKDLEEG
QLLRGFVKSVQ-PSGVLVGLGPSVTGLAQHPHVSQHNQSKNAPYDRHLPEGKLLTAKVLR
----------------LNHQESLVELSLLPDATGKQDARSAPLRQPPPKQEGRETEAVER
NHEGKA----KEKQQQKQKEKRTGKGQD--GAQPPSK---------DKKEPQKPQAK--K
LGKRPHPESG------SEQEIGSKKQKKAVLSEED----DSGVEVYYREGEEE-AEEMSM
------------------------------LPKEKLTRPAEAPRLQLSSSFVWDVGLDTL
TP-ALPPHRESSDSEEDE-KPEQATQKK-KSKKERELEKQKAEKELSRLEEALMDPGRQP
ESAEDFDRLVLSSPSSSLLWLQYMAFHLQATEIEKARAVAERALKTISFRE-EQEKLNVW
VALLNLENMYGSQESLTKVFERAVQYNEPLKVFLHLADIYTKSEKFQEAGELYNRMLKRF
RQEKAVWVKYGAFLLRRGKAEACHHVMQRALECLPKKEHVD
PF05843 // ENSGT00390000012228_0_Domain_7 (1902, 2007)
VIAKFAQLEFQLGDAERAR
AIFESTLSIYPKRTDVWSVYIDMIIKHGSQKEA-RDIFERVIHLSLAPKRMKFFFKRYLD
YEKQHGSEKDVQAVKAKALEYVEAKSTVVD---
ENSSBOP00000027832 (view gene)
-MATLEESFPRGGTRK--IHKPEKAFQQSVEQDNLFDIS---TEEGSTKRK-KSQKVPAK
T----KKLKMEKRESSKSAREKFEILSVESLCEGMRILGCVKEVNELELVISLPNGLQGF
VQVTEICDAYTKKLNEQVTQEQPLKDLFHLPELFSPGMLVRCVVSSLGVTERGKKSVKLS
LNPKNVNRVLSAEALKPGMLLTGTVSSLEDHGYLVDIGVDGTRAFLPLLKAQENIRQKNK
GAKLKVGQYLNCIIEEVKGNGGVVHLSIGHSEVSAAIATEEQSWTLNNLLPGLVVKAQVQ
KVTPFGLMLNFLTFFTGVVDFMHLDPKKAGTYFSNQAVKACILCVHPRTRVVRLSLRPIF
LQPGRPLSRLSCQHLGAVLNDVPVHGFFKKAGAIFRLKDGVLAYARL------SHLSDSK
NVFSPEAFKPGNTHKCRIIDYSQMDELALLSLRTSIIEAQYLRYHDI
PF00575 // ENSGT00390000012228_0_Domain_2 (468, 614)
KPGAVVKGTVLTI
KPYGMLVKVGEQMRGLVPPMHLADILMKNPEKKYHIGDEVKCRVV---------------
------------------------------------------------------------
----------KVA
ENSGT00390000012228_0_Linker_2_4 (614, 756)
VLNSEPSKERMLLSFKLLRDPEPKKE--PAGHNQKKGKAINVGQLVD
VKVLEKTKDGLEVAVLPH--NTCAFLPTSHLSDHVTNGPLLHHWLQAGDTLHRVL---CL
SQSEGHILLCRKPALVSAVEGGQDPKNFSEIHPGM
PF00575 // ENSGT00390000012228_0_Domain_4 (756, 823)
LLVGFVKSIKDYGVFIQFPSGLSGL
APKAIMSDKFVTSTSDHFVEGQTVVAKVTNVDEEKQRMLLSL
ENSGT00390000012228_0_Linker_4_5 (823, 1077)
RLSDCGLGDLATTSLLLL
SQCLEELQGVRSLMS--NR-DSVLIQTLAEMTPGMFLDLVVQEVLEDGSVVFSGGPVPNL
-VLRASRYHRGGQEVESGQKKKVVILNVDLLKLEVHVSLHQDLVNRK-AKKLRKGSEHQA
IVQHLEKSFAIASLVA--TGHLVAFSLTSHLNDTFRFDSEKLQVGQGVSLTLKTTEPGVT
GLLLAVEGPAAKRTMRPTRKDSETVDEDE-----------EVDPALTVGTIKKHTL
PF00575 // ENSGT00390000012228_0_Domain_5 (1077, 1139)
SIGD
MVTGTVKSIKPTHVVVTLKDGIIGCIHASHILDDVPEGTSPTTKLKVGKTVTARVIGGRD
MKTFKFLPISHPRFVRTVPELSVRPSELE------DGHTALNTDSVSPMEKIKQYQAGQT
VTCFLKKYNVVKKWLEVEIAPDIRGRIPLLLTSLSFKVLKHPDK-KFRVGQA-LRATVVG
PD-SSKAFLRLSL-IGPHKLEEGEVAMGRVVKVTPNEGLTVSFPFGKIGTVSLFHVSDSY
SEMPLEDFVPQKVVRCYILSAEDNVLTLS---LRSSRTNPETKSKVEDPEINSIQDIKEG
QLLRGYVRSIQ-PHGVFFGLGPSVVGLARYPYVSQHSPSKKALYNKHLPEGKLLTARVLR
----------------LNHQKNLVELSFLPGDTGEPDVLSASLEVPCSEQEERKTEAEEK
DQKGEKKNQKRN-----K---KNQKRLEE--VELPSK---------EKQQPQKPQAQ--K
RGRQEHQEPG------SEQERVSKKPKKAGPSEED----DSLLDVYYREGEEE-GEETNM
------------------------------LSKEKRTKPAEAPRLQLSSGFAWNVGLDSL
TP-ALPPLAESSDSEEDE-KPHQATK--KKSKKERELEKQKAEKELSRIEEALMDPGRQP
ESADDFDRLVLSSPNSSILWLQYMAFHLQATEIEKARAVAERALKTISFRE-EQEKLNVW
VALLNLENMYGSQESLTKVFERAVQYNEPLKVFLHLADIYAKSEKFQEAGELYNRMLKRF
RQEKA
PF05843 // ENSGT00390000012228_0_Domain_7 (1866, 2009)
VWIKYGAFLLRRSQAGASHCVLQRALECLPSKEHVDVIAKFAQLEFQLGDPERAK
AIFENTLTTYPKRTDVWSVYIDMTIKHGSQKDV-RDIFERVIHLSLAPKKMKFFFKRYLD
YEKQHGTEKDVQAVKAKALEYVEAKSSVED---
ENSFCAP00000002199 (view gene)
----MEESFPRGGTRKTHKSE--KAFQQSVEQDNLFDIS---TEEESTKRK-KSQKGPAK
T----KKLKIEKRENSKSIREKFEILSIESLCEGMRILGCVKEVNELELVVSLPNGLKGF
VQVTEICDAYTKKLSEQVAQEEPLKDLARLPELFSPGMLVRCVVSSVGFTEGGKKSVKLS
LNPKNVNEVLSAEALKPGMLLTGTVSSLEDHGYLVDIGVGGARAFLPLQKAQEYIRQKNK
GAEMKVGHYLNCVIEEVKGNGGVVGLSIGHSEVSTAIATEEQNWTLNNLLPGLVVKAQVQ
KVTPHGLILNFLSFFTGLVDFMHLDPKKAGTYFSNQTVRACVLCVHPRTRAVRLSLRPIF
LQPGRSLTRLSCQHLGAVLEDVPVQSFSSKAGATFRLKDGALAYARL------SHLSDSK
NVFNAEAFKPGNTHKCRIIDYSQMDELALLSLRTSVIEAQYLRYHDI
PF00575 // ENSGT00390000012228_0_Domain_1 (468, 538)
KPGALVKGTVLTI
KPYGMLVKVGEQIRGLVPPIHLADILIKNPEKKYHIGDEVKCRVLLCDPEAKKLMMTLKK
TLIESKLPAITCYADAKPGLQTHGFILRVKDYGCIVKFYNDVQGLVPKHELSA-EYVPDP
ERVFYTGQVVKVAVLNCEPSKERMLLSFKLLGDPK--RE--HTGHSQKKRRAVSVGQLVD
VKVLEKTKDGLEVAVLPH--NVPAFLPIPHLSDHVANGPLLYHWLQAGDILHRVL---CL
SQSEGHVLLCRKPALVSTVEGGQDPKSFSEIHPGMLLI
PF00575 // ENSGT00390000012228_0_Domain_4 (759, 823)
GFVKSIKDYGVFVQFPSGLSGL
APKAIMSDKFVTSTSDHFVEGQTVVAKVTNVDEEKQRMLLSL
ENSGT00390000012228_0_Linker_4_5 (823, 1077)
RLSDCGLGDLATTSLLLL
SQCLEERQGVRSLMS--SR-DSVLIQTLAEMIPGMVLDLEVQEVLEDGSVVFSEGPVPGL
-VLRASRYHRAGQEVEPGQKKKAVILNIDMLKLEVHVSLCHDLVNRK-AKKLKKGSEHQA
IVQHLEESFAVASLVE--TGHLAAFSLTSHLNDTFRFDSEKLQVGQGVSLTLKTTEPGVT
GFLLAVEGPATKRTVRQTRKDSETVDEDE-----------EADPALVVGAVKKHTL
PF00575 // ENSGT00390000012228_0_Domain_5 (1077, 1139)
SIGD
MVTGTVKSIKPTHVVVTLEDGIIGCIHASHILDDVPVGTSPTAKLKVGKTVTARVIGGRD
MKTFKFLPISHPRFIRTIPELSVRPSELE-----KDGCTALNTHSVSPLEKIKQYQAGQT
VICFLKKYNVVKKWLEVEIAPDIRGRIPLLLTSLSFKVLKHPDK-KFRIGQA-LKATVVG
PD-SSKAFLCLSL-IGPHKLEKGEVAMGRVVKVTPKEGLTVSFPFGKMGTVSIFHVSDSY
SEMPLEDFIPQKVVRCYVLSATDHVLTLS---LRSS------------------------
------------------SLGPSVVGLAQYPHVSQYSPSKKALYNRYLPEGKLLTAKVLS
----------------LNRQKNLVELSFLPGDTGKPDVFPASLGLPLLKQEERKMEAEEQ
EHKGEEEQ---QKKNQKRKGKKNEEGQE--AVRPPGK---------EKSESQKPQAK--K
QGKRPRREPA------SEQEGVKKKQKKAAPSEED----DSGVEVYYREGEEE-VEERSV
------------------------------LPKGKPTRPAEVPRLQLSSGFIWDVGLDSL
TP-ALPPRGESSDSEEDD-KPQQSTQ-K-RSKKERMLEKQKAEKELSRIEEALMDPGRQP
ESADDFDRLLLSSPNSSILWLQYMAFHLQATEIEKARAVAERALKTISFRE-EQEKLNVW
VALLNLENMYGSPESLTKVFERAVQYNEPLKVFLHLADIYTKSEKFQEAGELYNRMLKRF
RQEKS
PF05843 // ENSGT00390000012228_0_Domain_7 (1866, 2008)
VWIKYGAFLLRRGQAGASHRVMQRALECLPNKEHVDVIAKFAQLEFQLGDAERAK
AIFENTLSTYPKRTDVWSVYIDMTIKHGSQKEV-RDIFERVIHLSLAPKRMKFFFKRYLD
YEKQHGTEKDVQAVKAKALEYVEAKSSVLED--
ENSP00000358812 (view gene)
-MANLEESFPRGGTRK--IHKPEKAFQQSVEQDNLFDIS---TEEGSTKRK-KSQKGPAK
T----KKLKIEKRESSKSAREKFEILSVESLCEGMRILGCVKEVNELELVISLPNGLQGF
VQVTEICDAYTKKLNEQVTQEQPLKDLLHLPELFSPGMLVRCVVSSLGITDRGKKSVKLS
LNPKNVNRVLSAEALKPGMLLTGTVSSLEDHGYLVDIGVDGTRAFLPLLKAQEYIRQKNK
GAKLKVGQYLNCIVEKVKGNGGVVSLSVGHSEVSTAIATEQQSWNLNNLLPGLVVKAQVQ
KVTPFGLTLNFLTFFTGVVDFMHLDPKKAGTYFSNQAVRACILCVHPRTRVVHLSLRPIF
LQPGRPLTRLSCQNLGAVLDDVPVQGFFKKAGATFRLKDGVLAYARL------SHLSDSK
NVFNPEAFKPGNTHKCRIIDYSQMDELALLSLRTSIIEAQYLRYHDIEPGAVVKGTVLTI
KSYGMLVKVGEQMRGLVPPMHLADILMKNPEKKYHIGDEVKCRVLLCDPEAKKLMMTLKK
TLIESKLPVITCYADAKPGLQTH
PF00575 // ENSGT00390000012228_0_Domain_3 (564, 628)
GFIIRVKDYGCIVKFYNNVQGLVPKHELST-EYIPDP
ERVFYTGQVVKVVVLNCEPSKERMLLS
ENSGT00390000012228_0_Linker_3_4 (628, 759)
FKLSSDPEPKKE--PAGHSQKKGKAINIGQLVD
VKVLEKTKDGLEVAVLPH--NIRAFLPTSHLSDHVANGPLLHHWLQAGDILHRVL---CL
SQSEGRVLLCRKPALVSTVEGGQDPKNFSEIHPGMLLI
PF00575 // ENSGT00390000012228_0_Domain_4 (759, 823)
GFVKSIKDYGVFIQFPSGLSGL
APKAIMSDKFVTSTSDHFVEGQTVAAKVTNVDEEKQRMLLSL
ENSGT00390000012228_0_Linker_4_5 (823, 1077)
RLSDCGLGDLAITSLLLL
NQCLEELQGVRSLMS--NR-DSVLIQTLAEMTPGMFLDLVVQEVLEDGSVVFSGGPVPDL
-VLKASRYHRAGQEVESGQKKKVVILNVDLLKLEVHVSLHQDLVNRK-ARKLRKGSEHQA
IVQHLEKSFAIASLVE--TGHLAAFSLTSHLNDTFRFDSEKLQVGQGVSLTLKTTEPGVT
GLLLAVEGPAAKRTMRPTQKDSETVDEDE-----------EVDPALTVGTIKKHTL
PF00575 // ENSGT00390000012228_0_Domain_5 (1077, 1139)
SIGD
MVTGTVKSIKPTHVVVTLEDGIIGCIHASHILDDVPEGTSPTTKLKVGKTVTARVIGGRD
MKTFKYLPISHPRFVRTIPELSVRPSELE------DGHTALNTHSVSPMEKIKQYQAGQT
VTCFLKKYNVVKKWLEVEIAPDIRGRIPLLLTSLSFKVLKHPDK-KFRVGQA-LRATVVG
PD-SSKTLLCLSL-TGPHKLEEGEVAMGRVVKVTPNEGLTVSFPFGKIGTVSIFHMSDSY
SETPLEDFVPQKVVRCYILSTADNVLTLS---LRSSRTNPETKSKVEDPEINSIQDIKEG
QLLRGYVGSIQ-PHGVFFRLGPSVVGLARYSHVSQHSPSKKALYNKHLPEGKLLTARVLR
----------------LNHQKNLVELSFLPGDTGKPDVLSASLEGQLTKQEERKTEAEER
DQKGEKKNQKRN-----E-K-KNQKGQEE--VEMPSK---------EKQQPQKPQAQ--K
RGGRECRESG------SEQERVSKKPKKAGLSEED----DSLVDVYYREGKEE-AEETNV
------------------------------LPKEKQTKPAEAPRLQLSSGFAWNVGLDSL
TP-ALPPLAESSDSEEDE-KPHQATI--KKSKKERELEKQKAEKELSRIEEALMDPGRQP
ESADDFDRLVLSSPNSSILWLQYMAFHLQATEIEKARAVAERALKTISFRE-EQEKLNVW
VALLNLENMYGSQESLTKVFERAVQYNEPLKVFLHLADIYAKSEKFQEAGELYNRMLKRF
RQEKA
PF05843 // ENSGT00390000012228_0_Domain_7 (1866, 2008)
VWIKYGAFLLRRSQAAASHRVLQRALECLPSKEHVDVIAKFAQLEFQLGDAERAK
AIFENTLSTYPKRTDVWSVYIDMTIKHGSQKDV-RDIFERVIHLSLAPKRMKFFFKRYLD
YEKQHGTEKDVQAVKAKALEYVEAKSSVLED--
ENSHGLP00000001915 (view gene)
-MAALEENFPRGGTRK--IHKSEKSYQQLVEHDNLFDIS---NEEESTKRK-KNQKGPAK
T----KKLKIEKREGGKSVKEKLEILSVESLCEGMRILGCVKEVNELELVISLPNGLQGF
VQVTEICDAYTKKLNEQVAQEEPLKDLLRLPELFSPGMLVRCVVSSVSITERGKKSVKLS
LNPKNVNRVLSAEAL
PF00575 // ENSGT00390000012228_0_Domain_0 (196, 268)
KPGMLLTGTVSSLEDHGYLVDIGVVGTRAFLPLQKAQEYIRQKNK
GAKLKVGQYLNCIIEEVKSSGGVASLS
ENSGT00390000012228_0_Linker_0_1 (268, 468)
IEQSAISTAIATQEQNWSLNNLLPGLVVKAQVQ
KVTQFGLTLNFLTFFTGLVDFMHLDSKKVGTYFSNQAVRACILCVHPRTRAVRLSLRPIF
LQPGRPLTQLSCQHLGAVMKDVPVQGFFNKAGATFKLKDGALAYAR------LSHLSDSK
NAFRPETFKPGNMHKCRITDYSPMDGLALLSLRTSVIEAQYLRYHDI
PF00575 // ENSGT00390000012228_0_Domain_1 (468, 539)
KTGAVVKGTVLTM
RPFGMLVKVGEQVRGLVPATHLADILMKNPEKKYQVGAEVKCRVLLCDPEAKQLIMTLKK
TLVTSKLPVITCYEDAKPGLQTHGVIHRAKDYGCIVRFYNDVQGLVPKHELGA-QCIPDP
EKAFYAGQVVKVAVLNCEPAKERMLLSFKLLSDPEPKNE--RVGCGQKKRKDVGVGQLVD
VKVLEKTKDGLQVAVLPH--NIPAFLPTPHLSDHVANGPLVHRWLQAGDTLHRVL---CL
SQSERQVLLCRKPALVSSVEAGQDPKSFSEIQ
PF00575 // ENSGT00390000012228_0_Domain_4 (753, 823)
PGMLLVGFVKSIKDYGVFVQFPSGLSGL
APKAIMSDKFVTNPSDHFVEGQTVVAKVTNVDEEKQRMLLSL
ENSGT00390000012228_0_Linker_4_5 (823, 1077)
RLSDCRLGGPASGSLLLL
SQCLEELQGVRSLMS--SR-DSVLVQALAEMTPGMVLNLVVQEVSEDGSVVFTGAPVRDL
-VLRASRYHRAGQEVESGQKKKAVILYVDMLGLEVHVSLRKELVNRK-AWKLKKGSVHQA
TVQHLEESFAVASVGE--TGHLVAFSLASHLNDTFRFDSEKLQVGQSVCLVLKTAEPGVT
GLLLAVEGPAARRVLRQPCKDSEMGDEGE-----------GADPALAAGPRKKHGL
PF00575 // ENSGT00390000012228_0_Domain_5 (1077, 1140)
AIGD
VVTGTVKSVKPTHVVVTLEDGVMGCVHASHVLDEVPEGAAPTATLKVGKTVTARVIGGRD
VKTFKFLPISHPRFIRTVPELSVRPSELE-----KDGHTVLNTYSASPVEKIQQYRAGQT
VTCFLKKYNVVKKWLEVEIAPDIRGRIPLLLTSLSFKVLKHPDK-KFQIGQA-LRATVVG
PD-SSKPFLCLSL-IGPHKLKKGEVAMGRVVKVSPSEGLTVAFPFGRTGTVSVFHVSDSY
SERPLQDFSPQKVVRCYVLSTANHVLTLS---LRLSRTNPETKSKVEDPEINSILDIKEG
QLLRGFVRSVE-PSGVLLGLGPSVEGLARFSHVSQCSLPKKGLYSKYLPEGRLLTARVL-
---------------RLDPSKNLVELSFLPGDTGKPDVMSVSPELLVQKQEEDVEV-KER
DRKGEKKRS------PKRKEKKNQKGQE--EGELPSK---------EQVRAKRP------
-GKRERLGSEGAQES------ANKRRKKAGPPEEE----DSGVEVYYREGAEEEAAEAEV
------------------------------LPTGTLTKPAEVPRLRLSSGFFWDVGLDTL
TP-ALPPRGENSDSEEDE-KPPHATQK--KSKKERELEKQKAEKELSRIEEALRDPGRQP
ESADDFDRLVLSSPSSSILWLQYMAFHLQATEIDKARAVAERALRTISFRE-EQEKLNVW
VALLNLENMYGSPESLSKVFERAVQYNEPLKVFLHLADIYAKSEKFQEAGELYNRMLKRF
RQEKS
PF05843 // ENSGT00390000012228_0_Domain_7 (1866, 2007)
VWIKYGAFLLRRGQAGASHRVLQRALECLPAKEHMDVITKFAQLEFQLGDAERAR
AIFENMLSTYPKRTDIWSVYIDMTIKHGSQKEV-RDIFERVIHLNLAPKKMKFFFKRYLD
YEKQHGSEKDVRAVKAKALEYVEARSSVLED--
ENSTTRP00000003151 (view gene)
-TATMEESFPRGGTRKTHKSEKEKAFQQSFEQDNLFDIS---TEEESTKRK-KIQKEPAK
T----KKLKVEKRESNKFVREKFEILSVEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXKLNEQVAQE-ELQDLVSLPELFSPGMLVRCVVSSLDITKRGKKNVKLS
LNPRNVNKVLSAEALKPGMLLTGTVSSLEDHGYLVDIGVSGARAFLPLQKAQEYIQQKNK
GAKLKVGHYLNCLIEEVKGNGGIVSLSVGYSEVSAAIATEEQNWTLNSLLPGLVVKAQVQ
KVTPFGLTLKFLSFFTGLVDFMHLDPKKGRTYFSNQPVRACVLCVHPRTRAVRLSLRAVF
LQPGRPLTRLSCQQLGAVLDDVPVQGFFGNAGATFRLTDGALAYARL------SHLSNSK
KVFKPETFKPGNTHKCRIIDYSQMDELALLSLRTSVIEAQFLSYHDIKPGALVKGKVMTI
KPYGMLVKVGRQIRALVPPMHLADILMKNPVKKYHVGDEVKCRVLLCDPEARKLMMTLKK
TLVESKLPAITCYA
PF00575 // ENSGT00390000012228_0_Domain_3 (555, 629)
DAKPGLQTHGFILRVKDYGCIVKFYNDVQGLVPRHELSA-EYIPDP
ESVFYTGQVVKVAVLNCEPSKERMLLSF
ENSGT00390000012228_0_Linker_3_4 (629, 750)
KLSGDPK--EE--CAGHSQKKKKAINAGQLVD
VKVLEKTKDGLQVAVLPH--NIPGFLPTSHLSDHVTNGPLLHCWLQAGDTLHRVL---CL
SEGEGRVLLCRKPALVSAVEGGQDPKSFS
PF00575 // ENSGT00390000012228_0_Domain_4 (750, 823)
EIHPGMLLIGFVKNIKDYGVFVQFPSGLSGL
APKAIMSDKFVTSTSDHFVEGQTVVAKVTNVDEEKQRMLLSL
ENSGT00390000012228_0_Linker_4_5 (823, 1075)
RLSDCTRGDLAATSLLLL
SQCLEERQGVRSLMS--NR-DSVLIQTLAEMTPGMVLDLEVQEVLGDGSVLFSEGPVPGL
-VLRASKYHRAGQEVESGQKKKVVVLNVDMLKLEVHVSLCHDLVNRK-AKKLKKGSEHQA
IVQYLEEPFALASLVE--TGQLAAFSLTSHLNDTFRFDSEKLQVGQGVSLTLQTTEPGVT
GLLLAVEGPAAKRTMRQTRKDSETVDEDE-----------EVDPALVLGAVRKH
PF00575 // ENSGT00390000012228_0_Domain_5 (1075, 1150)
TLSIGD
MVTGTVKSIKPTHVVVTLEDGIIGCIHASHILDDVPVGTSPTAKLKVGKKVTARVIGGRD
MKTFKFLPISHPRFIRTIPELSVRPSELE-----KDGHTSLNTHSVSRLEKIKQYQAGQT
VTCFLKKYNVVKKWLEVDIAPDIRGLL------IHFSSLKHPDK-KFRIDR--LKTTVVG
PD-SSKAFLCLSL-IGPHKLEKGEVAMGRVVKVLPKEGLTVSFPFGKIGRVSIFHVSDSY
SETPLENFTPQKIVRCYVLSATGPVLTLS---LRSSRTNPETKSKITDPEINSIQDIEEG
QLLRGYVKSVQ-PSGVLLGLGPSVTGLAQYPHVSQYSLSKDAPYDRYLPEGKLLTAKVLS
----------------LNRRENLVELSIPADDTGKPDVFSASLGLPLPKQEGRETEAEER
DHKGEEEKEE--RKNQKQKEKRIGKGQE--GAQLPSK---------EKKEPRKPQAK--K
LGKRPRPESG------SEQESGNKRQRRTAPSEED----DSGVEVYYREGEEE-VEETGV
------------------------------RPQXXXXXXXXXXXXXXXXXXXXXXXXXXX
XX-XXPPREESSDSEEDE-KPEQVTQK--KSRKERELEKQRAEKELSRIEEALMDPRRQP
ESAEDFDRLVLSSPSSSILWLQYMAFHLQATEIEKARAVAERALKTISFRE-EQEKLNVW
VALLNLENMYGSQGSLTKVFERAVQYNEPLKVFLHLADIYTKSEKFQEAGELYNRMLKRF
RQEKAVWIKYGAFLLRRGQAGASHRVMQRALECLPKKEHVDVIAKFAQLEFQLGDAERAK
AIFENTLSTYPKRTDVWSVYIDMLIKRGSQKEV-RDIFERVIHLSLAPKRMKFFFKRYLD
YEKQHGTEKDVQAVKAKALEYVEAKSSMWED--
MGP_CAROLIEiJ_P0049066 (view gene)
-MANLEESFPRGGTRK--PHKPEKSSQQVVEQDNLFDVS---TEEGPIKRK-KSQKGPAT
T----KKLKIEKRKSIKSMKEKFEILSLESLCEGMRILGCVKEVSELELVVSLPNGLQGF
VQVTEVCDAYTQKLNEQVAQEEPLEDLLRLPELFSPGMLVRCVVSNLDVTESGKKSVKLS
VNPKRVNKVLSAEALR
PF00575 // ENSGT00390000012228_0_Domain_0 (197, 268)
PGMLLTGTVSSLEDHGYLVDIGVGGTRAFLSLQKAQEYIRQKNK
GAKFKVGQYLTCVVEEVKSNGGVVSLSVEHSEVSSAFATEEQRWNLNNLLPGLLVKAQVQ
KVTQFGLQLNFLTFFTGLVDFMHLEPKKMGSYSSNQTVKACILCVHPRTRVVRLSLRPIF
LHPGRPLTRISYQQLGAVLDDVPVQGFFKNAGVIFRLKDGVLAYARV------SHLSDSK
KAFNAEAFKPGSTHKCRIIDYSQMDELALLSLRKSIIAAPFLRYHDIKTGTVVKGTVLAI
KPFGILVKVGEQIKGLVPSMHLADIMMKNPEKKYSPGDEVKCRVLLCDPEAKKLIMTLKK
TLVTSKLPLLTCYEGAKPGLR
PF00575 // ENSGT00390000012228_0_Domain_3 (562, 628)
THGVIIRVKDYGCIVKFYNDVQGLVPKHELST-QHIPDP
EKVFYTGQVVKVAVLSCEPSKERMLLS
ENSGT00390000012228_0_Linker_3_4 (628, 754)
FRLLSDSGPKDP--SVESSQKKTGAVNIGQLVD
VKVLEKTKTGLEVAILPH--NTPAFLPTPHLSDHTANGPLLHHWLQTGDTLHRVL---CL
SQSERHILLCRKPALVSTVEGGQDPKSLSEIQP
PF00575 // ENSGT00390000012228_0_Domain_4 (754, 823)
GMLLIGFVKCIKEYGVFVQFPSGLSGL
SPKTIMSDKFVTTPSEHFVEGQTVVAKVTNVDESKQRMLLSLRLSDCSLGDSASTSFLLL
CQCLEELQGIRSLMS--NQ-DSVLIQTLADMTPGMVLDAVVHEVLEDGSVVFSSDPVPDL
-VLRASKYHRAGQEVEPGQKKKVVVLHVDMLKLEVHVSLHQDLVNRK-PRKLRKSSRHQG
IVQHLEESFAVASLVE--TGHLVAFSLISHLNDTFHFDSEKLRVGQGVCLTLKTTEPGVT
GLILAVEGPASKRTRMPVRRDSETVDDKGEEKEEE--EEEKEEEDLTVKAKKRHSLAIGD
KVTGTIKAVKGTHVVVTLADGFVGCIHASRILDDIPVGTSPTTTLKAGKKVTARVIGGRD
VKTSKFLPISHPRFVLTILELSVRPSELK-----G-SYSALNTHSVSPVEKIRQYQAGQT
VTCFFKKYNVMKKWLEVDIGPDIRGRIPLLLTSLSFKVLKHPDK-KFKIGQA-IEATVVD
PD-VPRAFLCLSL-IGPYRLEEGEVAMGRVMKVVPNRGLTVSFPFGKVGKVSMFHLSDSY
SEAPLEDFCPQKIVRCYILSTAHRVLTLS---LRSSRTNRETKNRIEDPEINSIEDVKEG
QLLRGYVKCVL-PSSVIIGLGPSVLGLTKYSHVSECVPPERELYNRCLPEGKLVTAKVLC
----------------VNPMKNLIELSLLPSDTGRPDVFSPDPEP---KQEERRGGAEG-
SQKRK--EKN-------------Q---------K--------------EELQKSQKG--G
RGKRERQESE------SEQELVNKRPKKSGAPEED----DSGVEVYYREGEDE-MEEPKL
------------------------------PPRGKQTKSTEVPRLHLSSGFVWDVGLDSL
TP-ALPLREESSDSED--EQPHQAKK--KKSKKERELEKQKAEKELSRIEEALMDPGRQP
ESADDFDRLVLSSPNSSILWLQYMAFHLQATEIEKARAVAERALKTISFRE-EQEKLNVW
VALLNLENMYGSQESLTKVFERAVQYNEPLKVFLHLADIYTKSEKFKEAGELYNRMLKRF
RQEKAVWIKYGAFVLGRSQAGASHRVLQRALECLPAK
PF05843 // ENSGT00390000012228_0_Domain_7 (1898, 2006)
EHVDVIVKFAQLEFQLGDVERAK
AIFENTLSTYPKRTDVWSVYIDMTIKHGSQQAV-RDIFERVIHLSLAPKRMKFFFKRYLD
YEKQHGTEKDVQAVKAKALEYVEAKSSALED--
ENSCHIP00000030449 (view gene)
-MAAMEESFPRGGTRKTHKSE--KAFQQSVEQDNLFDIS---TEEESTKRK-KTQKGPAK
T----KKVKVETRESSKFVREKFEILNVESLCEGMRILGCVKEVNELELVISLPNGLQGC
VQVTEICDAYTEKLNEQVAQEEPLQDLVGLPELFSPGMLVRCVVSSLDTTKWGKKNVMLS
LNPKNVNRVLSAETL
PF00575 // ENSGT00390000012228_0_Domain_0 (196, 267)
KPGMLLTGTVSSLEDHGYLVDIGVSGARAFLPLQKAQEYIRQKNK
GARLKVGQYLNCLIEEVKGSGGVVTL
ENSGT00390000012228_0_Linker_0_1 (267, 468)
SVGHSEVSAAIATEEQSWTLNSLLPGLVVKAQVQ
KVTPLGLTLKFLSFFSGLVDFMHLDPKRAGTYFSNQQVRACVLCVHPRTRAVRLSLHPVF
LQPGRPLTRLLCQQLGAVLDDVPVQGFFGNAGATFKLKDGALAYARR------NHLSNSK
KTFKPEAFKPGNTHKCRIIDYSQMDELALLSLRTSIIEAQFLWYHDI
PF00575 // ENSGT00390000012228_0_Domain_1 (468, 538)
KPGALVKGKVLTI
KPHGMVVKIGKQIRGLVPTMHLADILIKNPEKKYHVGDEVKCRVLLCDPKAKKLMMTLKK
TLVESKLPAITCYDDAKPGLQTHGFILRVKDYGCIVKFYNDVQGLVPRHELSA-EYVPDP
ESVFYTGQVVKVVVLNCEPSKERMLLSFRLLSDPK--QE--CEGQSQKKKKAVSAGQLVD
VKVLEKTKDGLKVAVLPH--NTPGFLPTAHLSDHVTNGPLLYHWLQTGDTLHRVL---CL
SASEERVLLCRKPALVSAVEGGQNPKSFSEIHPGMLLI
PF00575 // ENSGT00390000012228_0_Domain_4 (759, 823)
GFVKNIKDYGVFVQFPSGLSGL
APKAILSDKFVTSTSDHFVEGQTVVAKVTNVDEEKQRMLLSL
ENSGT00390000012228_0_Linker_4_5 (823, 1077)
RLSDCTLGDLATTSLLLL
SQCLEERQGVRSLMS--NR-DSVLIQTLAEMTPGMALDLEVQEVLEDGSVLFSEGPVPGL
-VLRASKYHRAGQELEPGQKKKAVILNVDMLKLEVHVSLCHDLVNRK-AKKLKKGSDLRA
IVQHLEESFAVASLVE--TGHLAAFSLTSHLNDTFRFDSEKLQVGQGVSLTLQTTEPGVT
GLLLAVEGPAAKRTMRQTRKDSETVDEDE-----------EVDPALVIGTVKKHTL
PF00575 // ENSGT00390000012228_0_Domain_5 (1077, 1139)
SIGD
MVTGTVKSIKPTHVVVTLEDGIIGCIHASHILDDVPVGTSPTAKLKVGKKVTARVIGGRD
MKTFKFLPISHPRFIRTIPELSVRPSELK-----EDGHTALNTHSVSPLEKIKQYQAGQT
VTCFLKKYNMVKKWLEVEIAPDVRGRIPLLLTSLSFKVLKHPDK-KFQIGQA-LKATVVG
PADSSKAFLSLSL-IGPHKLKKGEVAMGRVVKVTPKEGLTVSFPFGRVGRVSMFHVSDSY
SETRLEDFTPQQIVRCYVLSAASPVLTLS---LRSSRTNPETKSKITDPEINSIKDLEEG
QLLRGFVKSVQ-PSGVLVGLGPSVTGLAQHPHVSQHNQSKNAPYDRHLPEGKLLTAKVLR
----------------LNHQESLVELSLLPDATGKQDARSAPLRQPPPKREGRETEAVER
NHEGKA----KEKQQQKQKEKRTGKGQE--GAQPPSK---------DKKEPQKPQAK--K
LGKRPHPESS------SEQEIGSKKQKKAVLPEED----DSGVEVYYREGEEE-AEEMSM
------------------------------LPKEKLTRPAEAPRLQLSSGFVWDVGLDTL
TP-ALPPHGESSDSEEDE-KPEQATQKK-KSKKERELEKQKAEKELSRLEEALMDPGRQP
ESAEDFDRLVLSSPSSSLLWLQYMAFHLQATEIEKARAVAERALKTISFRE-EQEKLNVW
VALLNLENMYGSQESLTKVFERAVQYNEPLKVFLHLADIYTKSEKFQEAGELYNRMLKRF
RQEKAVWVKYGAFLLRRGKAEASHHVMQRALECLPKKEHVD
PF05843 // ENSGT00390000012228_0_Domain_7 (1902, 2006)
VIAKFAQLEFQLGDAERAR
AIFESTLSIYPKRTDVWSVYIDMIIKHGSQKEA-RDIFERVIHLSLAPKRMKFFFKRYLD
YEKQHGSEKDVQAVKAKALEYVEAKSAMVD---
ENSMFAP00000025042 (view gene)
-MAALEESFPRGGTRK--IHKPEKAFQQSVEQDNLFDIS---TEEGSTKRK-KSQKGPAK
T----KKLKIEKRESSKSAREKFEILSVESLCEGMRILGCVKEVNELELVISLPNGLQGF
VQVTEICDAYTKKLNEQVTQEQPLKDLLHLPELFSPGMLVRCVVSSLGITDRGKKSVKLS
LNPKNVNRVLSAEALKPGMLLTGTVSSLEDHGYLVDIGVDGTRAFLPLLKAQEYIRQKNK
GAKLKVGQYLNCIIEKVKGNGGVVSLSVGHSEVSTAIATEEQSWTLNNLLPGLVVKAQVQ
KVTPFGLTLNFLTFFTGVVDFMHLDPKKAGTYFSNQAVRACILCVHPRTRVVRLSLRPIF
LQPGRPLTRLSCQNLGAVLDDVPVQGFFKKAGATFRLKDGVLAYARL------SHLSDSK
NVFNPEAFKPGNTHKCRIIDYSQMDELALLSLRTSIIEAQYLRYHDI
PF00575 // ENSGT00390000012228_0_Domain_1 (468, 538)
EPGAVVKGIVLTI
KSYGMLVKVGEQMRGLVPPMHLADILMKNPEKKYHIGDEVKCRVLLCDPEAKKLMMTLKK
TLVESKLPVITCYADAKPGLQTHGFIIRVKDYGCIVKFYNNVQGLVPKHELST-EYIPDP
ERVFYTGQVVKVAVLNCEPSKERMLLSFKLSSDPEPKKE--PAGHSQKKGKAINIGQLVD
VKVLEKTKDGLEVAVLPH--NIRAFLPTSHLSDHVANGPLLHHWLQAGDILHRVL---CL
SQSEGHVLLCRKPALVSTVEGGQDPKNFSEIHPGMLLI
PF00575 // ENSGT00390000012228_0_Domain_4 (759, 823)
GFVKSIKDYGVFIQFPSGLSGL
APKAIMSDKFVTSTSDHFVEGQTVAAKVTNVDEEKQRMLLSL
ENSGT00390000012228_0_Linker_4_5 (823, 1077)
RLSDCALGDLATTSLLLL
SQCLEELQGVRSLMS--NR-DSVLIQTLAEMTAGMFLDLVVQEVLEDGSVVFSGGPVPDL
-VLRASRYHRAGQEVESGQKKKVVILNVDLLKLEVHVSLHQDLVNRK-AKKLRKGSEHQA
IVQHLEKSFAIASLVE--TGHLAAFSLTSHLNDTFRFDSEKLQVGQGVSLTLKTTEPGVT
GLLLAVEGPAAKRTMRPTRKDSETVDEDE-----------EVDPALTVGTVKKHTL
PF00575 // ENSGT00390000012228_0_Domain_5 (1077, 1139)
SIGD
MVTGTVKSIKPTHVVVTLEDGIIGCIHASHILDDVPEGISPTTKLKVGKTVTARVIGGRD
MKTFKFLPISHPRFVRTIPELSVRPSELE------DGHTALNTHSVSPVEKIKQYQAGQT
VTCFLKKYNVVKKWLEVEIAPDIRGRIPLLLTSLSFKVLKHPDK-KFRVGQA-LRATVVG
PD-SSKAFLCLSL-IGPHKLEEGEVAMGRVVKVTPNEGLTVSFPFGKIGTVSIFHVSDSY
SETPLEDFVPQKVVRCYILSTADSVLTLS---LRSSRTNPETKSKVEDPEINSIQDIKEG
QLLRGYVGSIQ-PHGVFFRLGPSVVGLARYSHVSQHSSSKKALYNKHLPEGKLLTARVLR
----------------LNHQKNLVELSFLPGDTGKPDLLSASLEGPLPKQEERKTEAEER
DQKGEKKNQKRN-----K-K-KNQKGQEE--VELPSK---------EKQQPQKPQAQ--K
RGGRERRESG------SEQERVSKKPKKAGPSEED----DSLMDVYYREGKEE-AEETNV
------------------------------LPKEKQTKPAEVPRLQLSSGFAWNVGLDSL
TP-ALPPLAESSDSEEDE-KPHQAMK--KKSKKERELEKQKAEKELSRIEEALMDPGRQP
ESADDFDRLVLSSPNSSILWLQYMAFHLQATEIEKARAVAERALKTISFRE-EQEKLNVW
VALLNLENMYGSQESLTKVFERAVQYNEPLKVFLHLADIYAKSEKFQEAGELYNRMLKRF
RQEKA
PF05843 // ENSGT00390000012228_0_Domain_7 (1866, 2008)
VWIKYGAFLLRRSQAGASHRVLQRALECLPSKEHVDVIAKFAQLEFQLGDTERAK
AIFENTLSTYPKRTDVWSVYIDMTIKHGSQKAV-RDIFERVIHLSLAPKRMKFFFKRYLD
YEKQHGTEKDVQAVKAKALEYVEAKSSVLED--
ENSCGRP00001004991 (view gene)
-MANLEESFPRGGTRK--SHKLEKSFQQAVEQDNLFDIS---TEEESTKRK-KTQKGPIK
A----KKLKLEKKEVSKSVREKFEILSVESLCEGMRILGCVKEVNELELVISLPNGLQGF
VQVTEICDAYTQKLNEQVTQEEPLEDLLRLPDLFSPGMLVRCVVSSLDITERGKKSVKLS
VNPKHVNKVLSAEALRPRMLLTGTVSSLEDHGYLVDIGVSGTRAFLSLHKAQEYIRQKNK
GANLKIGQYLTCLVDEVKSNGAVVGLSIEHSEISSAFATEEQSWNLNNLLPGLVVKAQVQ
KVTEFGLQLNFLTFFTGLVDFMHLEPKKIGAYSSKQTVKACILCIHPRTRVVRLSLRPVF
LQPGRPLTRISYQQLGAVLDKVPVQGFFKKAGATFRLKDGALAYARL------SHLSDSK
KTFNPEAFKPGSTHKCRIIDYSQMDELALLSLRKSIITAQFLSYHDIKTGTVVKGTVLAI
KPFGILVKVGEQMRGLVPSMHLGDIMMKNPEKKYHLGDEVKCRVLLCDPEAKKLIMTLKK
TLITSKLPAIMCYEDAKPGLQT
PF00575 // ENSGT00390000012228_0_Domain_3 (563, 628)
HGVIIRVKSYGCIVKFYNSVQGLVPKHELSD-QHIPDP
EKVFYTGQVVKVAVLNSEPSKERLLLS
ENSGT00390000012228_0_Linker_3_4 (628, 754)
FKLLSDSEPKND--SVEISQKKGRAVNIGQLVD
VKVLEKTKDGLEVAILPH--NTPAFLPTPHLSDHVANGPLLHHWLQAGDTLHRVL---CL
SQGEKHILLCRKPALVSTVEGGQDPKSLSEIQP
PF00575 // ENSGT00390000012228_0_Domain_4 (754, 823)
GMLLIGFVKSIKDYGVFVQFPSGLNGL
APKAIMSDKFVTTPSDHFVVGQTVVAKVTNVDEEKQRMLLSL
ENSGT00390000012228_0_Linker_4_5 (823, 1077)
RLSDCSLGDPASTSFILL
CQCLEELQGVRSLMS--NQ-DSVLMQTLAEMTPGMVLDVMVQEVLEDGSVVFSG-HVPDL
-ILKASKYHRAGQEVASGQKRRVVVLHVDMLKLEVHVSLRQDLVHRK-ARKLRKSSRHQG
IVQHLEESFAVASLME--TGQLVAFSLTSHLNDTFHFDSEKLHVGQGVCLTLKTTEPGVT
GLILAVEGPASKRTSTPARRDSETADDKEE---------EEENSDLTVRTKKKHGL
PF00575 // ENSGT00390000012228_0_Domain_5 (1077, 1139)
AIGD
KVTGTIKSVKATHVVVTLEDGIIGCIHASRILDDVPVGTSPTTTLKVGEKVTARVIGGRD
LKTSKFLPISHPRFVLTILELSIRPSELK-----KDGYSALNTHSESPLEKTEQYQAGQT
VTCFFKKYNAIKKWLEVDVAPDIRGRIPLLLTSLSFKVLKHPDK-MFQVGQA-LRATVVG
SD-VPKAFLCLSL-IGPYKLEQGEIAMGRVLSVVPNKGLTISFPFGKVGKVSLFHVSDSY
SEALLEDFFPQKIVRCYVLSTEHHVLTLS---LRSSRTNRETKSKVEDPEINSIQDVKEG
QLLRGYVKSVL-SHGVLVELGPSVVGLAQYSHVSQCRPPEKELYDSYLPKGKLVTAKVLR
----------------VNPERSQVELSLLPSDTGKPDLFSASPEPPLLNGEERKEGAKER
VRKGEEKKS--QK---R--KEKNQKGQE--EAELSSQ---------EKKE---SQRH--R
QGKRERHEPV------SEQERVNKRPKKSGTPEED----DSGVEVYYREGEDE-MEQPGV
------------------------------LPMGKQTKPAEVPRLQLSSGFVWDVGLDSL
TP-ALPPRGESSDSEED-EKPHQAKK--KKGKKERELEKQKAEKELSRIEEALMDPGRQP
ESADDFDRLVLSSPNSSILWLQYMAFHLQATEIEKARAVAERALKTISFRE-EQEKLNVW
VALLNLENMYGSQESLMKVFERAVQYNEPLKVFLHLADIYTKSEKFKEAGELYSRMLKRF
RQEKAVWIKYGAFVLGRSQAGTSHRVLQRALECLPTKEH
PF05843 // ENSGT00390000012228_0_Domain_7 (1900, 2008)
VDVISKFAQLEFQLGDAERAK
AIFENTLSTYPKRTDVWSVYIDMTIKHGSQKEV-RDIFERVIHLSLAPKRMKFFFKRYLD
YEKQHGTEKDVQAVKAKALEYVEAKSSVLED--
ENSCJAP00000033833 (view gene)
-MATLEESFPRGGTRK--IHKPEKAFQQSIEQDNLFDIS---TEEGSTKRK-KSQKVPAK
T----KKLKIEKRESSKSAREKFEILSVESLCEGMRILGCVKEVNELELVISLPNGLQGF
VQVTEICDAYTKKLNEQVMQEQPLKDLFHLPELFSPGMLVRCVVSSLSITERGKKSVKLS
LNPKNVNRVLSAEVLKPGMLLTGTVSSLEDHGYLVDIGVDGTRAFLPLLKAQEYIQQKNK
GAKLKVGQYLNCIIEEVKGSGGVVHLSIGHLEVSTAIATEEQSWTLNNLLPGLVVKAQVQ
KVTPFGLTLNFLTFFTGVVDFMHLDPKKAGTYFSNQAVKACILCVHPRTRVVRLSMRPIF
LQPGRPLSRLSCQHLGAVLTDVPVQGFFKKAGATFRLKDGVLAYARL------SHLSDSK
NVFNPEAFKPGNTHKCRIIDYSQMDELALLSLRTSIIEAQYLRYHDIKPGAVVKGTVLTI
KPYGMLVKVGEQMRGLVPHMHLADILMKNPEKKYHIGDEVKCRVLLCDPEAKKLVMTLKK
TLVESKLPAITCFADAKPGLQTH
PF00575 // ENSGT00390000012228_0_Domain_3 (564, 628)
GFIIRVKDYGCIVKFYSDVQGLVPKHELST-EYIPDP
ERVFYTGQVVKVAVLNSEPSKERMLLS
ENSGT00390000012228_0_Linker_3_4 (628, 756)
FKLLRDPEPKKE--PAGHNQKKEKAINVGQLVD
VKVLEKTKDGLEVAVLPH--NTHAFLPTSHLSDHVTNGPLLHHWLQAGDTLHRVL---CL
SQSEGHVLLCRKPALVSTVEGGQDPKNFSEIHPGM
PF00575 // ENSGT00390000012228_0_Domain_4 (756, 823)
LLVGFVKSIKDYGVFIQFPSGLSGL
APKAIMSDKFVTSTSEHFVEGQTVVAKVTNVDEEKQRMLLSL
ENSGT00390000012228_0_Linker_4_5 (823, 1077)
RLSDCGLGDLATTSLLLL
SQCLEELQGVRSLMS--NR-DSVLIQTLAEMTPGMFLDLVVQKVLEDGSVVFSGGPVPNL
-VLRASRYHRGGQEVESGQKKKVVILNVDLLKLEVLVSLHQDLVNRK-AKKLRKGSEHQA
VVQHLEKSFAIASLVE--TGHLVAFSLTSHLNDTFRFDSEKLQVGQGVSLTLKTTEPGVT
GLLLAVEGPAAKRTMRLTRKDSETVDEDE-----------EVDPALTVGTIKKHTF
PF00575 // ENSGT00390000012228_0_Domain_5 (1077, 1139)
SIGD
MVTGTVKSIKPTHVVVTLKDGIIGCIHASHILDDVPEGTSPTTKLKVGKTVTARVIGGRD
MKTFKFLPISHPRFVRTVPELSVRPSELE------DGHTALNTHSVSPMEKIKRYQAGQT
VTCFLKKYNVVKKWLEVEIAPDIRGRIPLLLTSLSFKVLKHPDK-KFRVGQA-LRATVVG
PD-SSKAFLRLSL-IGPHKLEEGEVAMGRVVKVTPNEGLTISFPFGKIGTVSLFHVSDSY
SETPLEDFVPQKVVRCYILSTEDNVLTLS---LRSSRTNPETKSKVEDPEINSIQDIKEG
QLLRGYVRSIQ-PHGVFFGLGPSVVGLARYPHVSQHSPSKKALYNKHLPKGKLLTARVLR
----------------LNHQKNLVELSFLPGDTGKPDVLSASLEVPLSEQEERKTGAEEK
DQKGEKKNQKRN-----K---KNQKQLEE--VELPSK---------EKQQPQKPQAQ--K
WGRQEHQEPG------SEQERVSKKPKKAGPSEED----DSLLDVYYREGEEE-GEETNM
------------------------------LSKEKQTKPAETPRLQLSSGFAWNVGLDSL
TP-ALPPLAESSDSEEDE-KPHQATK--KKSKKERELQKQKAEKELSRIEEALMDPGRQP
ESADDFDRLVLSSPNSSILWLQYMAFHLQATEIEKARAVAERALKTISFRE-EQEKLNVW
VALLNLENMYGSQESLTKVFERAVQYNEPLKVFLHLADIYAKSEKFQEASELYNRMLKRF
RQEKA
PF05843 // ENSGT00390000012228_0_Domain_7 (1866, 2009)
VWIKYGAFLLRRSQAGASHCVLQRALECLPSTEHVDVIAKFAQLEFQLGDPERAK
AIFENTLTTYPKRTDVWSVYIDMTIKHGSQKDV-RDIFERVIHLSLAPKKMKFFFKRYLD
YEKQHGTEKDVQAVKAKALEYVEAKSSVED---
ENSMAUP00000015579 (view gene)
-MANLEESFPRGGTRK--SHKSEKSSQPAVEQDNLFDIS---TEEEPTKRK-KSQKGPVK
V----KKLKTEKKEVSKSVREKFEILSVESLCEGVRILGCVKEVNELELVISLPNGLQGF
VQVTEICDAYTQKLNEQVAQEEPLEDLPRLPDLFSPGMLVRCVVSSLDITERGKKSVKLS
VNPKHVNKVLSAEALRPGMLLTGTVSSLEDHGYLVDIGVSGTRAFLSLQKAQEYIRQKNK
GANLKTGQYLTCLVEEVKSNGAVVGLSIEHSGISSAFATEEQSWNLNNLLPGLLVKAQVQ
KVTEFGLQLNFLTFFTGLVDFMHLEPKKIGAYSSKETVKACILCIHPRTRVVRLSLRPVF
LQPGRPLTRISYQQLGAVLDKVPVQGFFKKAGATFRLNDGALAYARL------SHLSDSK
KAFNPEAFKPGSTHRCRIIDYSQMDELALLSLRKSIITAQFLSYHDIKTGTVVKGTVLAI
KPFGILVKVGEQMRGLVPSMHLADIMMKNPEKKYHLGDEVKCRVLLCDPEAKRLIMTLKK
TLVSSKLPAIMCYEDAKPGLQT
PF00575 // ENSGT00390000012228_0_Domain_3 (563, 628)
HGVIIRVKSYGCIVKFYNNVQGLVPKHELSD-QHIPDP
EKVFYTGQVVKVAVLNSEPSKERLLLS
ENSGT00390000012228_0_Linker_3_4 (628, 754)
FKLLSDSEPKND--SVENSQKKGRAVNIGQLVD
VKVLEKTKDGLEVAILPH--NIPAFLPIPHLSDHVANGPLLHHWLQAGDTLHRVL---CL
SQGEKHILLCRKPALVSTVEGGQDPKSLSEIQP
PF00575 // ENSGT00390000012228_0_Domain_4 (754, 823)
GMLLIGFVKSIKDYGVFVQFPSGLNGL
APKSIMSDKFVTTPSDHFVVGQTVVAKVTNVDEEKQRMLLSLRISDCSLGDSASTSFILL
CQCLEELQGVRSLMS--NQ-DSVLIQTLAEMTPGMVLNVVVQEVLQDGSVVFSGGPVPDL
-ILKASRYHRAGQELESGQKRRVVVLHVDMLKLEVHVSLHQDLVNRK-ARKVSSLTVS--
VFE--------------------------ALYLDFHT--R--LTAQG-------------
-------------------------------------------------------RSLGL
P-------------------------------------------------VS--------
-----YI--CASGTHLVFFSFPFSHYELK-----NDGYSALNTHSVSPMEKTQQYQAGQI
VTCFFKKYNTIKKWLEVDVAPDVRGRIPVLLSSLSCKVLKHPDK-RFQVGQA-LRATVVS
SD-VPKAFLCLSL-IGPYKLEQGEIVMGRVLSVVPNKGLTISLPFGKIGKVSLFHVSDSY
SEALLEDFFPQKIVRCYVLSTEHHVLTLS---LRSSRTNRETKSKIEDPEINSIQDVEEG
QLLRGYVKCVL-SHGVLVDLGPSVVGLAHYSHVSRCSPPEKELYDSYLPKGKLITAKVLR
----------------VNPERSQIELSLLPSDTGKPDVFSASPEPRLLNQEERKEGAKER
GLKGEEKKKKSQK---R--KEKTQKGQE--EVELCSQ---------EKKE---SQRP--R
QGKRERHEPA------CEQEGVNKRPKKSGTPEED----DSGVEVYYREGDDE-TEQPGV
------------------------------LPRGKQTKPAEVPRLQLSSGFVWDVGLDSL
TP-ALPLRGESSDSEED-EKPQQAKK--KKGKKERELEKQKAEKELSRIEEALMDPGRQP
ESADDFDRLLLSSPNSSILWLQYMAFHLQATEIEKARAVAERALKTISFRE-EQEKLNVW
VALLNLENMYGSQESLTKVFERAVQYNEPLKVFLHLADIYTKSDKFKEAGELYSRMLKRF
RQEKA
PF05843 // ENSGT00390000012228_0_Domain_7 (1866, 2008)
VWIKYGAFVLRRSEAGTSHRVLQRALECLPTKEHVDVISKFAQLEFQLGDAERAK
AIFENTLSTYPKRTDVWSVYIDMTIKHGSQKEV-RDIFERVIHLSLAPKRMKFFFKRYLD
YEKQHGTEKDVQAVKAKALEYVEAKSSVLED--
ENSCATP00000043592 (view gene)
-MAALEESFPRGGTRK--IHKPEKAFQQSVEQDNLFDIS---TEEGSTKRK-KSQKGPAK
T----KKLKIEKRESSKSAREKFEILSVESLCEGMRILGCVKEVNELELVISLPNGLQGF
VQVTEICDAYTKKLNEQVTQEQPLKDLLHLPELFSPGMLVRCVVSSLGTTDRGKKSVKLS
LNPKNVNRVLSAEALKPGMLLTGTVSSLEDHGYLVDIGVDGTRAFLPLLKAQEYIRQKNK
GAKLKVGQYLNCIVEKVKGNGGVVSLSVGHSEVSTAIATEEQSWTLNNLLPGLVVKAQVQ
KVTPFGLTLNFLTFFTGVVDFMHLDPKKAGTYFSNQAVRACILCVHPRTRVVRLSLRPIF
LQPGRPLTRLSCQNLGTVLDDVPVQGFFKKAGATFRLKDGVLAYARL------SHLSDSK
NVFNPEAFKPGNTHKCRIIDYSQMDELALLSLRTSIIEAQYLRYHDI
PF00575 // ENSGT00390000012228_0_Domain_1 (468, 538)
EPGAVVKGIVLTI
KSYGMLVKVGEQMRGLVPPMHLADILMKNPEKKYHIGDEVKCRVLLCDPEAKKLMMTLKK
TLVESKLPVITCYADAKPGLQTHGFIIRVKDYGCIVKFYNNVQGLVPKHELST-EYIPDP
ERVFYTGQVVKVAVLNCEPSKERMLLSFKLSSDPEPKKE--PAGQSQKKRKAINIGQLVD
VKVLEKTKDGLEVAVLPH--NIRAFLPTSHLSDHVANGPLLHHWLQAGDILHRVL---CL
SQSEGHVLLCRKPALISTVEGGQDPKNFSEIHPGMLLI
PF00575 // ENSGT00390000012228_0_Domain_4 (759, 823)
GFVKSIKDYGVFIQFPSGLSGL
APKAIMSDKFVTSTSDHFVEGQTVAAKVTNVDEEKQRMLLSL
ENSGT00390000012228_0_Linker_4_5 (823, 1077)
RLSDCALGDLATTSLLLL
SQCLEELQGVRSLMS--NR-DSVLIQTLAEMTPGMFLDLVVQEVLEDGSVVFSGGPVPDL
-VLRASRYHRMGQEVESGQKKKVVILNVDLLKLEVHVSLHQDLVNRK-AKKLRKGSEHQA
IVQHLEKSFAIASLVETETGHLAAFSLTSHLNDTFRFDSEKLQVGQGVSLTLKTTEPGVT
GLLLAVEGPAAKRTMRPTRKDSETVDEDE-----------EVDPALTVGTVKKHTL
PF00575 // ENSGT00390000012228_0_Domain_5 (1077, 1139)
SIGD
MVTGTVKSIKPTHVVVTLEDGIIGCIHASHILDDVPEGISPTTKLKVGKTVTARVIGGRD
MKTFKFLPISHPRFVRTIPELSVRPSELE------DGHTALNTHSVSPVEKIKQYQAGQT
VTCFLKKYNVVKKWLEVEIAPDIRGRIPLLLTSLSFKVLKHPDK-KFRVGQA-LRATVVG
PD-SSKAFLCLSL-IGPHKLEEGEVAMGRVVKVTPNEGLTVSFPFGKIGTVSIFHVSDSY
SETPLEDFVPQKVVRCYILSTADSVLTLS---LRSSRTNPETKSKVEDPEINSIQDIKEG
QLLRGYVGSIQ-PHGVFFRLGPSVVGLARYSHVSQHSPSKKALYNKHLPEGKLLTARVLR
----------------LNHQKNLVELSFLPGDTGKPDLLSASLEGPLPKQEERKTEAEER
DQKGEKKNQKRN-----E-K-KNQKGQEE--VELPSK---------EKQQPQKPQAQ--K
RGGRERRESG------SEQERVSKKPKKAGPSEED----DSLMDVYYREGKEE-AEETNV
------------------------------LPKEKQTKPAEVPRLQLSSGFAWNVGLDSL
TP-ALPPLAESSDSEEDE-KPHQATK--KKSKKERELEKQKAEKELSRIEEALMDPGRQP
ESADDFDRLVLSSPNSSILWLQYMAFHLQATEIEKARAVAERALKTISFRE-EQEKLNVW
VALLNLENMYGSQESLTKVFERAVQYNEPLKVFLHLADIYAKSEKFQEAGELYNRMLKRF
RQEKA
PF05843 // ENSGT00390000012228_0_Domain_7 (1866, 2008)
VWIKYGAFLLRRSQAGASHRVLQRALECLPSKEHVDVIAKFAQLEFQLGDAERAK
AIFENTLSTYPKRTDVWSVYIDMTIKHGSQKAV-RDIFERVIHLSLAPKRMKFFFKRYLD
YEKQHGTEKDVQAVKAKALEYVEAKSSVLED--
ENSPPAP00000006256 (view gene)
-MANLEESFPRGGTRK--IHKPEKAFQQSVEQDNLFDIS---TEEGSTKRK-KSQKGPAK
T----KKLKIEKRESSKSAREKFEILSVESLCEGMRILGCVKEVNELELVISLPNGLQGF
VQVTEICDAYTKKLNEQVTQEQPLKDLLHLPELFSPGMLVRCVVSSLGITDRGKKSVKLS
LNPKNVNRVLSAEALKPGMLLTGTVSSLEDHGYLVDIGVDGTRAFLPLLKAQEYIRQKNK
GAKLKVGQYLNCIVEKVKGNGGVVSLSVGHSEVSTAIATEQQSWNLNNLLPGLVVKAQVQ
KVTPFGLTLNFLTFFTGVVDFMHLDPKKAGTYFSNQAVRNAWWRMPVV------------
-----PATQ----------EDLLSL-----------AYPQSLGTLQL------SHLSDSK
NVFNPEAFKPGNTHKCRIIDYSQMDELALLSLRTSIIEAQYLRYHDIEPGAVVKGTVLTI
KSYGMLVKVGEQMRGLVPPMHLADILMKNPEKKYHIGDEVKCRVLLCDPEAKKLMMTLKK
TLIESKLPVITCYADAKPGLQTH
PF00575 // ENSGT00390000012228_0_Domain_3 (564, 628)
GFIIRVKDYGCIVKFYNNVQGLVPKHELST-EYIPDP
ERVFYTGQVVKVVVLNCEPSKERMLLS
ENSGT00390000012228_0_Linker_3_4 (628, 759)
FKLSSDPEPKKE--PAGHSQKKGKAINTGQLVD
VKVLEKTKDGLEVAVLPH--NIRAFLPTSHLSDHVANGPLLHHWLQAGDILHRVL---CL
SQSEGRVLLCRKPALVSTVEGGQDPKNFSEIHPGMLLI
PF00575 // ENSGT00390000012228_0_Domain_4 (759, 823)
GFVKSIKDYGVFIQFPSGLSGL
APKAIMSDKFVTSTSDHFVEGQTVAAKVTNVDEEKQRMLLSL
ENSGT00390000012228_0_Linker_4_5 (823, 1077)
RLSDCGLGDLAITSLLLL
NQCLEELQGVRSLMS--NR-DSVLIQTLAEMTPGMFLDLVVREVLEDGSVVFSGGPVPDL
-VLKASRYHRAGQEVESGQKKKVVILNVDLLKLEVHVSLHQDLVNRK-ARKLRKGSEHQA
VVQHLEKSFAIASLVE--TGHLAAFSLTSHLNDTFRFDSEKLQVGQGVSLTLKTTEPGVT
GLLLAVEGPAAKRTMRPTRKDSETVDEDE-----------EVDPALTVGTIKKHTL
PF00575 // ENSGT00390000012228_0_Domain_5 (1077, 1139)
SIGD
MVTGTVKSIKPTHVVVTLEDGIIGCIHASHILDDVPEGTSPTTKLKVGKTVTARVIGGRD
MKTFKYLPISHPRFVRTIPELSVRPSELE------DGHTALNTHSVSPVEKIKQYQAGQT
VTCFLKKYNVVKKWLEVEIAPDIRGRIPLLLTSLSFKVLKHPDK-KFRVGQA-LRATVVG
PD-SSKTFLCLSL-TGTHKLEEGEVAMGRVVKVTPNEGLTVSFPFGKIGTVSIFHMSDSY
SETPLEDFVPQKVVRCYILSTADNVLTLS---LRSSRTNPETKSKVEDPEINSIQDIKEG
QLLRGYVGSIQ-PHGVFFRLGPSVVGLARYSHVSQHSPSKKTLYNKHLPEGKLLTARVLR
----------------LNHQKNLVELSFLPGDTGKPDVLSASLEGQLTKQEERKTEAEER
DQKGEKKNQKRN-----E-K-KNQKGQEE--VEMPSK---------EEQQPQKPQAQ--K
RGGQECRESG------SEQERVSKKPKKAGLSEED----DSLVDVYYREGKEE-AEETNV
------------------------------LPKEKQTKPAEAPRLQLSSGFAWNVGLDSL
TP-ALPPLAESSDSEEDE-KPHQATI--KKSKKERELEKQKAEKELSRIEEALMDPGRQP
ESADDFDRLVLSSPNSSILWLQYMAFHLQATEIEKARAVAERALKTISFRE-EQEKLNVW
VALLNLENMYGSQESLTKVFERAVQYNEPLKVFLHLADIYAKSEKFQEAGELYNRMLKRF
RQEKA
PF05843 // ENSGT00390000012228_0_Domain_7 (1866, 2008)
VWIKYGAFLLRRSQAAASHRVLQRALECLPSKEHVDVIAKFAQLEFQLGDAERAK
AIFENTLSTYPKRTDVWSVYIDMTIKHGSQKDV-RDIFERVIHLSLAPKRMKFFFKRYLD
YEKQHGTEKDVQAVKAKALEYVEAKSSVLED--
ENSTGUP00000010637 (view gene)
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--------------RCYILSIENGKIQLS---LRQSRLNPKINSKVEDIEITSIKDVKKG
QLVRGYVKSIT-PSGVFFGLSTSLLGRILFQNVSPYFVQKHSLYKKYLPEGKLLTAKVLG
----------------VNRKEKHIELSLLPEDTGMPSVLPESLGLPQYGAEKEKREADYE
EKREQ-----PKMKTKR--RRGNDEMTGKIPVLSQKDEAE--KLCRLG-KKIKLHWRLQR
SKT-----SFWE----AK-----PKKRKICQADEN----DSGIEVYYREEEEDDQEEEAA
K------------------------------KKSMVRKPGEAPRLQVSVGFTWEED-SAM
DIPVLDQKEESSESE-EEEDMQSKLK--KRTKKEKELEKQKKEKELCKVEAALMDPSRQP
QSADDFDRLVLGSPNSSILWLQYMAFHLQATEIEKARAVAERALKTISFRE-EQEKLNVW
VALLNLENMYGTEETLMKVFERAVQYNEPLKVFQHLCDIYASSEKYKQAEELYHTMLKRF
RQEKSVWLKYASFLLKQGQAEATHRLLERALKALPTKEHVDVISR
PF05843 // ENSGT00390000012228_0_Domain_7 (1906, 2009)
FAQLEFHSGDTEHAK
ALFESTLSSYPKRTDIWSIYMDIMIKHGSQKEV-RDIFERVIHLSLAPKKMKFFFKRYLD
YEKKFGTAESVLAVKRAALEYVETKSSLADT--
ENSPVAP00000003958 (view gene)
-MATMEESFPRGGTRKTHKSE--KAFKQSVEQDNLFDIS---TEEESTKRK-KSQKGPVK
T----KKLKIEKRESSKSAREKFEILSIESLCEGMRILGCVKEVNELELVISLPNGLQGF
VQVTEICDAYTKKLNEQVAQEEPLKDLVHLPELFSPGMLVRCVVSSLGITERGKKSVKLS
LNPKNVNKVLSAE
PF00575 // ENSGT00390000012228_0_Domain_0 (194, 269)
ALKPGMLLTGTVSSLEDHGYLVDIGVGGARAFLPLQKAQEYNRQKNK
GAKLKVGQYLNCIIEEVKGSGGVVTLSIDHSEVSTAIATEEQNWTLNNLLPGLVVKAQIQ
KVTPLGLTLNFLSFFTGLVDFMHLDPKKAGTYFSNQAVKACVLCVHPRTRVVRLSLRPVF
LHPGRSLTRLTCQHLGAVLDDVPVQSFFNKAGATFRLKDGSLAYARL------SHLSDSK
TVFSPEAFKPGNTHKCRIIDFSQMDELAVLSLRTSIIEAQYFRYHDIKPGALVKGTVLTI
KPYGMLVNVGEQIRGLVPPMHLADIQMKNPEKKYHIGDEVTCRVLLCDPEAKKLMITLKK
TLVESKLPAITCYA
PF00575 // ENSGT00390000012228_0_Domain_3 (555, 629)
DAKPGLQTHGFILRVKDYGCIVKFYNDVQGLVPKHELSA-EYVPDP
ERVFYAGQVVKVAVLNCEPARERMLLSF
ENSGT00390000012228_0_Linker_3_4 (629, 750)
KLLGEPE--KE--RAGHSQKKRKAVNVGQLVD
VKVLEKTRDGLEVAVLPH--NIPAFLPTSHLSDHVANGPLLYHWLQAGDTLHRVL---CL
SQSEGRIILCRKPALVSTMEGGQDPKSFS
PF00575 // ENSGT00390000012228_0_Domain_4 (750, 823)
EIQPGMLLIGFVKSIKDYGVFIQFPSGLSGL
APKAVMSDKFVTSTSDHFVEGQTVVAKVTNVDEEKQRMLLSL
ENSGT00390000012228_0_Linker_4_5 (823, 1075)
RLSDCALGDLATTSLLLL
SQCLEEWQGVRSLMS--NR-DSVLIQTLAEMTPGMVLDLEVQEVLEDGSVIFSEGPVPGL
-VLRASKYHRAGQEVESGQKKKAVILNVDMLKLEVHVSLCHNLVNRK-AKKLKKGSEHQA
IVQHLEESFAIASLVE--TGHLAAFSLTSHLNDTFRFDSEKLQVGQGVSLTLKTTEPGVT
GLLLAVEGPAAKRTMRRTQKDSETVDEDD-----------EADPAMVVGTLKKH
PF00575 // ENSGT00390000012228_0_Domain_5 (1075, 1137)
TLSIGD
MVTGTVKSVKPTHVVVTLKDGIIGCIHASHILDDVPVGTCPTAKLKVGKTVTARVIGGRD
MKTFXXXXXXXXXXXXXXXXXXXXXXELE-----KDGHTALNTHSVSPSEKIKQYQAGQT
VTCFLKKYNVVKKWLEVEVAPDIRGRIPILLTSLSFKVLKHPDK-KFQIGQA-LKATVVG
PD-SSKAFLCLSL-IGPHKLEKGEVAMGRVVKVTPKKGLTVSFPFGKIGRVSIFHVSDSY
SEAPLEDFTPQKIVRCYVLSTAGHVLTLS---LRSSRTNPETKSKIPDPEINSIQDIEEG
QLLRGYVKSVE-PHGVLLGLGPSVVGLAQYPHVSQYSPSKKTLYNRHLPEGKLLTAKVLS
----------------VSHQKNLVELSFLPGETGRPDVFPASLGLPLLKQEERQLEAEVR
DHKGEKKE---QKKNQPRKEKKNQKGQE--EEPLPSK---------EKSEPQKPGAR--K
QGKRPRPESG------KEQERMK-KQKKAAPSEED----DSGVEVYYREGEEE-TET-RV
------------------------------LLAEKQTRPAEVPRLKLSSGFVWDVGLDSL
TP-ALPPRGESSDSEEDE-KSQQAT-KK-KSKKERELEKQKAEKELSRIEEALMDPKRQP
ESADDFDRLVLSSPNSSILWLQYMAFHLQATEIEKARAVAERALKTISFRE-EQEKLNVW
VALLNLENMYGSQESLTKVFERAVQYNEPLKVFLQLADIYTKSEKFQEASELYNRMLKRF
RQEKTVWIKYGAFLLHRGQAEASHRVMQRSLECLPNKEHVDVIAKFAQLEFQLGDAERAK
ALFENTLSIYPKRTDVWSVYIDMTIKHGSQKEV-RDIFERVIHLSLAPKRMKFFFKRYLD
YEKQHGTEKDVQSVKAKALEYVEAKSSVLED--
ENSVPAP00000006886 (view gene)
-MATMEESFPRGGTRK--THKSEKAFQYSVEHDNLFDIS---TEEESTKRK-KNQKGPAQ
T----KKLKIEKRESSKFVREKFEILNKESLCEGMRILGCVKEVNELDLVISLPNGLQGV
VQVTEICDAYTEKLNEQVAQEEPLQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XAKLKVGHYLNCTIEEVKGNGGVVSLSIGHSEVSAAIATEEQNWTHNNLLPGLVVKAQVQ
KVTPLGLTLKFLSFFTGLVDFMHLDPKKAGTYFSNQPXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXQTF---PQHWDQLKDGALAYAWL------SHLSNSK
KLFKPETFKPGNTHKCRIIDYSQMDELALLSLRTSIIEAQFLWYH
PF00575 // ENSGT00390000012228_0_Domain_1 (466, 539)
DIKPGVLVKGTVLTI
KPYGILVKVSKQVRGLVPPMHLADILMKNPEKKYHIGDEVKCRVLLCNPEAKKLIMTLKK
TLVESKLPAITCYADAKPGLQTHGFILRVKDYGCIVKFYNDVQGLVPKHELSA-EYVPDP
ESVFYTGQVVKVVFLSCEPSKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXX--XXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---XX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXIMSDKFVTSTSDHFVEGQTVVAKVTNVDEEKQRMLLSLRLSDCTLGDLATTSLLLL
TQCLEERQGIRSLMS--NR-DSVLIQTLAEMTPGMLLDLEVQEVLEDGCVLFSEGPVPGL
-VLRASRYHRAGQEVESGQKKKVVILSIDMLKLEVHVSLCHDLVNRK-AKKLKKGSEHQA
IVQHLEESFAVASLVE--TGHLAAFSLTSHLNDTFHFDSEKLQVGQGVSLTLETTEPGVT
GLLLAVEGPAVKRTMRKTRKDSETVDEDE-----------EVDPALVVGTIKKH
PF00575 // ENSGT00390000012228_0_Domain_5 (1075, 1150)
TLSIGD
VVTGTVKSIKPAHVVVTLEDGIIGCIHASHILDDVPVGTAPTSKLKVGKKITARVIGGRD
MKTFKFLPISHPRFIRTIPELSVRPSELE-----KDGHTALNTHSVSPLEKIKQYQAGQT
VTCFLKKYNVVKKWLEVEIAPDIRGRIPLLLTSLNFKVLKHPDK-KFRIGQA-LKATVVG
PD-SSKAFLCLSL-IGPHKLEKGEVAMGRVVKVTPKEGLTVSFPFGKIGRVSIFHVSDSY
SETPLEDFTPQKIVXXXXXXXXXXXXXXX---XXXXXTNPETKSKIADPEI--IQDIVKG
QLLRGNLKSVQ-PSGVLLXXXXXXXXXXXXXXXXXXXXXXXXX----------------X
XXXXXXXXXXXXXXXXVNHRGDLVQLSFLPRDTGKPDVFPASLGLPLRKQDERETGAEER
DHTRQEKKGKRNSH--KKKDKSNGQGP-E-EVQLPSK---------ENKVPQKPQAK--K
PGKRPHPESG------REHEHVNKKQKKAAPSEED----DSGVEVYYREGEEE-MEEPSV
------------------------------PPR---------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------
ENSECAP00000018688 (view gene)
-MATMEESFPRGGTRKPHKSD--KAFQQSVEQDNLFDIS---TEQESTKRK-KNQKGPAK
T----KKLKVEKRESSKSIREKFDILSIESLCEGMRILGCVKEVNELELVISLPNGLQGF
VQVTEICDAYTKKLSEQVAQEEPLKDLARLPELFSPGMLVRCVVSSLSVTEKGKKNVKLS
LNPKNVNEVLSAEAL
PF00575 // ENSGT00390000012228_0_Domain_0 (196, 268)
KPGMLLTGTVSSLEDHGYLVDIGVAGARAFLPLQKAQEYIRQ-NK
GAKLKVGQYLNCIIEEVKGSGGVVSLSIGHSEVSTAIATEEHNWTLNNLLPGLVVKAQVQ
KVTPLGLTLNFLSFFTGLVDFMHLDPKKAGKYFSNQAVRACVLCVHPRTRAVRLSLRPVF
LQPGRPLTRLSCQHLGAVLDNVPVQGFFSKAGATFRLKDGALAYARL------SHLSDPK
NVFNPETFKPGNTHKCRIIDYSQMDELALLSLRTSVIEAQYLRYHDIKPGALVKGTVLTI
KPYGMLVKVGEQIRGLVPPMHLADILMKNPEKKYRTGDEVKCRVLLCDPEARKLMMTLKK
TLVESKLPAITCYADAKPGLQTH
PF00575 // ENSGT00390000012228_0_Domain_3 (564, 628)
GFILRVKDYGCIVKFYNDVQGLVPKHELSA-EYVPDP
ERVFYAGQVVKVVVLNCEPSKERMLLS
ENSGT00390000012228_0_Linker_3_4 (628, 753)
FKLLSDSK--KE--CAGHNQKKRRAVNVGQLMD
VKVLEKTKDGLEVAVLPH--NIPAFLPTPHLSDHVANGPLLYHWLQAGDTLHRVL---CL
SQSERHVLLCRKPALVSTVEGGQDPKSFSEIH
PF00575 // ENSGT00390000012228_0_Domain_4 (753, 823)
PGMLLIGFVKSIKDYGVFVQFPSGLSGL
APKAIMSDKFVTSTSDHFVEGQTVVAKVTNVDEEKQRMLLSL
ENSGT00390000012228_0_Linker_4_5 (823, 1078)
RLSDCTLGDLATTSLLLL
SQCLEERQGVRSLMS--NR-DSVLIQTLAEMTPGMVLDLEVQEVLEDGSVLFSEGPVPGL
-VLRANRYHRAGQEVESGQKKKAVILNVDMLKLEVHVSLCHDLVNRK-AKKLKKGSEHQA
IVQHLEESFAVASLVE--TGHLAAFSLTSHLNDTFRFDSEKLHVGQGVSLTLKTTEPGVT
GLLLAVEGPAAKRTMRQTRKDSEAVDEDE-----------EVDATLVVGTVKKHTLS
PF00575 // ENSGT00390000012228_0_Domain_5 (1078, 1139)
IGD
MVTGTVKSIKPTHVVVTLADGIIGCIHASHILDDVPAGTSPTAKLKVGKTVTARVIGGRD
VKTFKFLPISHPRFIRTIPELSVRPSELE-----KDGHTALNTHSVSPLEKIKQYQAGQT
VTCFLKKYNVVKKWLEVEIAPDIRGRIPLLLTSLSFKVLKHPDK-KFRIGQA-LKATVVN
PD-SSKAFLCLSL-IGPHNLEKGEVAMGRVVKVTPKKGLTVSFPFGKIGRVSIFHVSDSY
SETPLEDFTPQKVVRCYVLSTAGHVLTLS---LRSSRTNPETKSKIADPEINSLKDIREG
QLLRGYVKSVQ-PHGVLFGLGPSVVGLAQYPHVSQYSPTEKALYNRHLPEGKLLTAKVLS
----------------LNHQKNLVELSFLPGDTGKPDVFPASLGLLLLKPEERRIEAEVD
REGEEE-----RKKNQKRKEKRSQKGQE--EAQLSSK----------KKEPQKPQAK--K
QGKRLRLESG------SGQERVNKKQKKAAPSEGD----DSGVEVYYREGEEE-IEETSV
------------------------------LPKGKPTRPAEVPRLQLSSGFVWDVGLDSL
TP-ALPLRGESSDSEEDE-KPQQSMQKK-KSKKERELEKQKAEKELSRIEEALMDPGRQP
ESADDFDRLVLSSPNSSILWLQYMAFHLQATEIEKARAVAERALKTISFRE-EQEKLNVW
VALLNLENMYGSQESLTKVFERAVQYNEPLKVFLHLADIYTKSEKFQEAGELYNRMLKRF
RQEKA
PF05843 // ENSGT00390000012228_0_Domain_7 (1866, 2008)
VWIKYGAFLLRRGQAGASHRVMQRALECLPVKEHVDVIAKFAQLEFQLGDAERAK
AIFENTLSTYPKRTDVWSVYIDMIIKHGSQKEV-RDIFERVIHLSLAPKRMKFFFKRYLD
YEKQHGTEKDVQAVKAKALEYVEAKSSVLED--
ENSSARP00000002339 (view gene)
-MADFEESFPRGGTRK--TPKSEKAPQRSVEQDNLFDVS---HEEESSTKRKKSQKGPAQ
A----KKLKIEKRESSKPVKEKFELLGVKVLCEGMRILGCVKEVKQLELVVSLPNGLQGF
VQVTEICDAYTKKLSEQMAQEEPLTEVASLPELFSPGMLVRCVVSSLGTTEKGKQTVKLS
LNPKKVNDVLSAD
PF00575 // ENSGT00390000012228_0_Domain_0 (194, 269)
ALKPGMLLTGTVSSLEDHGYLVDIGVAGARAFLPLKKVQE----KSK
GAKLQVGQYLNCTIEEVKGSGGVVRLSV
ENSGT00390000012228_0_Linker_0_1 (269, 466)
GHAEGSAALATEEQNWTLNNLLPGLVVRAQVQ
KXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVRACVLAVHPRTREVRLSLRPVF
LQSGRPLSRLSCQNLGAVLEDVPVQGFFHKAGATFKLKDGSLAYARL------GQLSDSK
KVFNPEAFKPGNLHKCRVVDYSPMDELAFLSLRTSVIEAQYLTYS
PF00575 // ENSGT00390000012228_0_Domain_1 (466, 521)
DIRPGELVKGTVLSM
KPFGMLVELSKQIRGLVPSLHLADVLMKNPEKKYKVGKEVKCRXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--DPNKEPEGPSQKKNQSVSTGQLVD
VKVLEKTPDGLEVAVLPH--NIRGFLPMSHLSDHVSNGPLLHHWLQEGDTLHKVL---CL
SQTEGHILLCRKPALVSTVEGGQNPKSFA
PF00575 // ENSGT00390000012228_0_Domain_4 (750, 823)
EIHPGMLLIGFVKCIKDYGVFVQFPSGLSGL
APKALMSDKFVTTTSDHFVEGQTVVAKVTHVDEEKQRMLLSL
ENSGT00390000012228_0_Linker_4_5 (823, 1075)
RLSDCSLGDRAATSLLLL
TQCLEEQQGVRCLMG--NR-DSVLIQTLAQMAPGMVLDLEVQEVLEDGSVVFSEGPVAGL
-VLRASRYHRAGQDVESGQKKKAVVLSVDLLKLEVHVSLLPDLLNQK-AKKLKKGSRHQA
VVQHLEESFAVASLAG--SGHLAAFSLTSHLNDTFHFDSEKLQVGQGVSLTLKTTQPGVT
GLLLAVEGPAATRTLTQPRKDSETVDEDE-----------ELDPALVASAGKRH
PF00575 // ENSGT00390000012228_0_Domain_5 (1075, 1150)
ALSIGD
LVTGTVKSVKPTHVLVSLEDGIVGSLHASHVLDDVPAGTVPTARFKVGKRVKVRV-GGXX
XXXXXYLPISHPRFIRAVPELSVRPSDPK------DGCATLNTDSVSPLEKLQQYQAGQT
VTCFLRKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XX-XXXXXXX-XXXXXXX
XXXXXXXXXXXXX-XXPHRLEEGDVAMGRVVKVTPTEGLTVSFPFGRTGSVSIFHVSDAY
LETPLEGFTPQQIVXXXXXXXXXXXXXXX---XXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXX-XXXXXXXLGPSVVGLAQHPHVSQHSPSHTELYHQHLPEGKLLTARVLS
----------------MNHQKGPVGLSLLPRDTGKPDVCPAAPSVPAGAQEREQSGGDPE
--------QRTPK----RK-----------KKQRPSK---------EEKEPPEPQARARA
RGKRGCPEPE------EQQEAVIKKQKKAAPAEEE----DSGVDVYYREGDEEESSAPQX
------------------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XX-XXXXXXXXXXXXXXX-XXXXXXXX--XXXXXXXXXXXXXXX-XXXX-XXXXX--XXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XDIFERVIHLSLAPKRMKFFFKRYLD
YEKQHGTETAVQAVKAKALEYVEARSAVPED--
ENSEEUP00000008507 (view gene)
-------------------------------------IS---TEERSIKRK-KSQKVPVK
T----KKLKIGKEESSKSLKEKFEILNVESLCEGMRILGCVKEVNELELVISLPSGLQGF
VQVTEICDAYTQKLNEQVAQEEPLKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XVTPLGLTLNFLTFFTGLVDFMHLDPKKAGKYSSNQTVKACILCIHPRTRAVRLSLRPTF
LQPGRPLTRLSCPNLGAVLEGIPVQGFFNKAGATFRLKDGSLAYAQL------SHLSNSK
KAFHPEAFKPGNTHKCRVIDYSQMDELTLLSLRTSIIEAPYLRYH
PF00575 // ENSGT00390000012228_0_Domain_1 (466, 539)
DIKPGTLVTGTVLTI
KPYGMLVKVGHQIRGLVHPTHLADILLKNPEKKYHIGDEVKCRVLLCDPEARKLSLTLKK
TLVESQLPLITSYANAKPGLQTHGFILRVKDYGCIVKFYDGVQGLVPKHELSA-EYVPDP
EKVFYVGQVVKVAVLNCEPAKERMLLSIKLLSDPK------RRGQKQKKKGAINVGQFVD
VKVLKKTKDGLEVAVLPH--NVPAFLPTPHLSDHVPNGPLLHHWLQEGDILHKVL---CL
SHSDGRPLLCRKPALVSTVEGGQDPKSFS
PF00575 // ENSGT00390000012228_0_Domain_4 (750, 823)
EIQPGMVLIGFVKSIKDYGVFVQFPSGLSGL
APKAIMSDKFVTFTRDHFVEGQTVVAKVTNVDEEKQRMLLSL
ENSGT00390000012228_0_Linker_4_5 (823, 1075)
RLSDCTLGNRATTSLLLL
SQCLEELQGVRSLMG--NR-ESVLIQTLAEMTAGMVLDLEVQEVMEDGSVLFSEGPVPGL
-VLKASKYHRAGQELEPRQKKKAVILNVDMLKLEVHVSLCQNLVNRK-SKKLKKGSEHKA
IVQHLEESFAIASLVE--TGQLVAFSLTSHLNDTFHFDSEKLQVGQGVSLTIKTTDPGVT
GLLLAVEGSAAKRTMRQTRKDSETVDEDE-----------EVDQALVVGSIKKH
PF00575 // ENSGT00390000012228_0_Domain_5 (1075, 1150)
TLSIGD
TVTGNVKSIKPTHVVVTLEDGIIGCIHASQILDDVPMGTSPTATLKVGKTVTARVIGGRD
VKTYKFLPISHPRFIRTIPELSVRPSELE-----KDSHTALNTHSVSPLEKIKQYQAGQT
VTCFLKKYNMVKKWLEVEIAPDVRGRIPLLLTSLSFKVLKHPDK-KFQVGQA-LKATVVD
SD-CSKTFLCLSL-IGPHKLEKGDVAMGRVETVTPNKGLTVSFPLGKVGQVDEFHVSDSY
SETPLEDFEPQKIVRCYVLSTAGSVLTLS---LRSSRTNPETKSKIVDPEINSIRDIQKG
QLLRGYVKAVE-SHGVLLRLGPSIVGLAQYPHVSQASPSQKELYNKYLPKGRLLTAKVLS
----------------LNRQKNLVELSFLPSDTGKPDVLSASLAVSLPKQGGKA-GTEER
DQKGREEKKNQ-----KKKEKQQQSGQE--ETKMPSK----------KKEPRKPQVK--K
QGKRLHSESE------SEQERVNKKQKKASPAEED----DSGVEVYYREGEEE-LKE-CV
------------------------------PPKEKHSKRAEMPRLQLSSGFVWDVGLDSL
TP-ALPPRGDSSDSEEDE-KPQQATK---KNKKERELEKQKAEKELSRIEEALMDPGRQP
ESADDFDRLVLSSPDSSILWLQYMAFHLQATEIEKARAVAERALKTISFRE-EQEKLNVW
VGLLNLENMYGSQESLTKVFERAVQYNEPLKVFLHLADIYTKSEKFQEAGELYNRMLKRF
RQEKAVWIKYGAFLLRRDQADASHRVMQRALECLPKKDHVDIIAKFAQLEFQLGDAERAK
AMFENTLSTYPKRTDVWSVYIDMSIKHGSQKEV-RNVFERVIHLSLAPKRMKFFFKRYLD
YEKQHGTEKDVQAVKAKALDYVEAKSSVVED--
ENSPEMP00000008883 (view gene)
-MANLEESFPRGGTRK--SHKAEKPSQQAAEPDNLFDIS---TEEKSTKRK-KSQKGPAK
T----KKLRTEKREASKSGREKFEILSTGSLCEGMRILGCVKEVNELELVISLPNGLQGF
VQVTDICDAYTQKLNEQVAQEEPLEDLLRLPDLFSPGMLVRCVVSSLDITEKGKKNVRLS
VNPKHVNKVLSAEALRPGMLLTGTVSSLEDHGYLVDIGVGGTRAFLSLQKAQEYIRQKNK
GAKLKVGQYLTCLVEEVKSNGGVVGLSIEHSEISSAVATEEQSWNLNNLLPGLVVKAQVQ
KVTQFGLQLNFLTFFTGLVDFMHLEPKKIGAYSSKQTVKACILCIHPRTRVVRLSLRPIF
LQPGRPLTRISYQQLGAVLDNVPLQGFFEKAGATFRLKDGVLAYARL------SHLSDSK
KTFSAEAFKPGSTHKCRIIDYSQMDELALLSLRKSVISAQFLRYHDI
PF00575 // ENSGT00390000012228_0_Domain_1 (468, 537)
KTGMVIKGTVLAI
RPFGILVKVGEQMRGLVPSMHLADIVMKNPEKKYHLGDEVKCRVLLCDPEAKKLLMTLKK
TLVTSKLPAITCYEDAKPGLQTHGVIVRVKAYGCIVKFYNSVQGLVPKHELSD-QHIADP
EKVFYTGQVVKVAVLNCEPSKERMLLSFKLLNDSEPKNE--SVENSQKKGRAVNVGQLVD
VKVLEKTKDGLEVAILPH--NIPAFLPTPHLSDHVANGPLLHHWLQAGDTLHRVL---CL
SQGEKHILLCRKPALVSTVEGGQDPKSLSEV
PF00575 // ENSGT00390000012228_0_Domain_4 (752, 823)
QPGMLLIGFVKSIKDYGVFVQFPSGLNGL
APKAIMSDKFVTTPSDHFVVGQTVVAKVTNVDEEKQRMLLSL
ENSGT00390000012228_0_Linker_4_5 (823, 1077)
RLSDCSLGDSASTSFLLL
CQCLEELQGVRSLMS--NQ-DSVLIQTLAEMTPGMVLDVVVQEVLEDGSVVFSGGPVPDL
-ILKASRYHRAGQEVESGQKRRVVVLHVDMLKLEVHVSLHQALVNRK-ARKLRKSSRHQG
IVQHLEESFGVASLME--TGHLVAFSLTSHLNDTFHFDSEKLQVGQGVCLTLKTTEPGVT
GLILAVEGPASKRTSRPARRDSETVDDKEE---------E-EETDLTVRTKKKHGL
PF00575 // ENSGT00390000012228_0_Domain_5 (1077, 1142)
AIGD
KVTGTIKSVKATHVVVTLEDGIMGCIHASRILDEVPVGTTPTTTLKVGEKVSARVIGGRD
VKTSKFLPISHPRFVLTILELSIRPSDLK-----KDGYSALNTHSVSPVEKTEQYQAGQT
VTCFFKKYNAIKKWLEVEVAPDIRGRIPLLLTSLSFKVLKHPDK-KFQIGQA-LRATVVD
SD-VPKAFLCLSL-IGPYRLEQGEIIMGRVLSVVPNKGLTISFPFGKIGKVSLFHVSDSY
SEALLEDFFPQKIVRCYVLSTEDRVLALS---LRSSRTNKETKSKIQDPEINSIQDIKEG
QLLRGYVKSVL-SDSVLVSLGPSVVGLARYSHVSPCGPPKKDLCDRYLPKGKLITAKILR
----------------VNPEKSRVELSLLPSDTGKPDVFSASPEPPLLNREERKEGAEER
DLKGEEKKR--QK---R--KEKNQKGQE--EAELSSQ---------EKKEPQKSQRS--R
QGKRERQEPA------REQERVTKRPKKSGAPEED----DSGVDVYYREGEDE-TEQPGV
------------------------------SPKVRQTKPAEAPRLQLSSGFIWDVGLDSL
TP-ALPLRGESSDSEEE-EEPRQAKK--KKGKKERELEKQKAEKELSRLEEALMDPGRQP
ESADDFDRLVLSSPNSSILWLQYMAFHLQATEIEKARAVAERALKTISFRE-EQEKLNVW
VALLNLENMYGSPESLTKVFERALQYNEPLKVFLHLADIYTKSEKFKEAGELYNRMLKRF
RQEKAVWIKYGAFVLGRSQAGASHRVLQRALECLPT
PF05843 // ENSGT00390000012228_0_Domain_7 (1897, 2006)
KEHVDVLAKFAQLEFQLGDAERAK
AIFENTLSTYPKRTDVWSVYIDMTIKHGSQKEV-RDIFERVIHLSLAPKRMKFFFKRYLD
YEKQHGTEKDVQAVKAKALEYVEAKSSGLED--
ENSRBIP00000002415 (view gene)
-MATLEESFPRGGTRK--IHKPEKAFQQSVEQDNLFDIS---TEEGSTKRK-KSQKGPAK
T----KKLKIEKRESSKSAREKFEILSVESLCEGMRILGCVKEVNELELVISLPNGLQGF
VQVTEICDAYTKKLNEQVTQEQPLKDLLHLPELFSPGMLVRCVVSSLGITDRGKKSVKLS
LNPKNVNRVLSAEALKPGMLLTGTVSSLEDHGYLVDIGVDGTRAFLPLLKAQEYIRQKNK
GAKLKVGQYLNCIVEKVKGNGGVVSLSVGHSEVSTAIATEEQSWTLNNLLPGLVVKAQVQ
KVTPFGLTLNFLTFFTGVVDFMHLDPKKAGTYFSNQAVRACILCVHPRTRVVRLSLRPMF
LQPGRPLTRLSCQNLGAVLDDVPVQGFFKKAGATFRLKDGILAYARL------SHLSDSK
NVFNPEAFKPGNTHKCRIIDYSQMDELALLSLRTSIIEAQYLRYHDI
PF00575 // ENSGT00390000012228_0_Domain_1 (468, 538)
EPGAVVKGIVLTI
KSYGMLVKVGEQMRGLVPPMHLADILMKNPEKKYHIGDEVKCRVLLCDPEAKKLMMTLKK
TLVESKLPVITCYADAKPGLQTHGFIIRVKDYGCIVKFYNNVQGLVPKHELST-EYIPDP
ERVFYTGQVVKVAVLNCEPSKERMLLSFKLSSDPEPKKE--PAGHSQKKGKAVNIGQLVD
VKVLEKTKDGLEVAVLPH--NIHAFLPTSHLSDHVANGPLLHHWLQAGDILHRVL---CL
SQSEGHVLLCRKPTLVSTVEGGQDPKNFSEIHPGMLLI
PF00575 // ENSGT00390000012228_0_Domain_4 (759, 823)
GFVKSIKDYGVFIQFPSGLSGL
APKAIMSDKFVTSTSDHFVEGQTVAAKVTNVDEEKQRMLLSL
ENSGT00390000012228_0_Linker_4_5 (823, 1077)
RLSDCALGDLATTSLLLL
SQCLEELQGVRSLMS--NR-DSVLIRTLAEMTPGMFLDLVVQEVLEDGSVVFSGGPVPDL
-VLRASRYHRAGQEVESGQKKKVVILNVDLLKLEVHVSLHQDLVNRK-AKKLRKGSEHQA
IVQHLEKSFAVASLVE--TGHLAAFSLTSHLNDTFRFDSEKLQVGQGVSLTLKTTEPGVT
GLLLAVEGPAAKRTMRPTRKDSETVDEDE-----------EVDPALTVGTIKKHTL
PF00575 // ENSGT00390000012228_0_Domain_5 (1077, 1139)
SIGD
MVTGTVKSIKPTHVVVTLEDGIIGCIHASHILDDVPEGISPTTKLKVGKTVTARVIGGRD
MKTFKFLPISHPRFVRTIPELSVRPSELE------DGHTALNTHSVSPVEKIKQYQAGQT
VTCFLKKYNVVKKWLEVEIAPDIRGRIPLLLTSLSFKVLKHPDK-KFRVGQA-LRATVVG
PD-SSKAFLCLSL-IGPHKLEEGEVAMGRVVKVTPNEGLTVSFPFGKIGTVSIFHVSDSY
SETPLEDFVPQKVVRCYVLSTTDSILTLS---LRSSRTNPETKSKVEDPEINSIQDIKEG
QLLRGYVGSIQ-PHGVFFRLGPSVVGLARYSHVSQHSPSKKALYNKHLPEGKLLTARVLR
----------------LNHQKNQVELSFLPGDTGKPDLLSASLEGPLPKQEERKTEAEER
DQKGEKKNQKKN-----E-K-KNQKGQEE--VELPSK---------EKQQPQKPQAQ--K
RGGRERRESG------SEQERVSKKPKKAGPSAED----DSLMDVYYREGKEE-AEETNV
------------------------------LPKEKQTKPAEVPRLQLSSGFAWNVGLDSL
TP-ALPPLAESSDSEEDE-KPHQATK--KKSKKERELEKQKAEKELSRIEEALMNPGRQP
ESADDFDRLVLSSPNSSILWLQYMAFHLQATEIEKARAVAERALKTISFRE-EQEKLNVW
VALLNLENMYGSQESLTKVFERAVQYNEPLKVFLHLADIYAKSEKFQEAGELYNRMLKRF
RQEKA
PF05843 // ENSGT00390000012228_0_Domain_7 (1866, 2008)
VWIKYGAFLLRRSQAGASRRVLQRALECLPSKEHVDVIAKFAQLEFQLGDAERAK
AIFENTLSTYPKRTDVWSVYIDMTIKHGSQKAV-RDIFERVIHLSLAPKRMKFFFKRYLD
YEKQHGTEKDVQAVKAKALEYVEAKSSVLED--
ENSETEP00000000662 (view gene)
-------------------------------------IS---TEEEPTKRK-KSQKGPEK
T----KKLKIEKKDSITPVKEKFEILRVESLCEGMRILGCVKEVNDLELVIGLPNGLQGF
VQVTEICDAYTRKLNEQVAQEDPLEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXLLTGTVSSQEDHGYLVDIGVSGNRAFLPLQKAHQDGRQKSK
GAKLKVGQYLNCVVEEVKGDGEVVRLSIGHLDVSTAIATEEQSWTLHNLLPGLVVKGQVQ
KVTPLGLTVNFLS-FTGLVDFMHLEPKKTGTYLSKQTVRACILSVHPRTRVVRLSLRPVF
LQPGRPLPRLSCQHLGAVLEGVPVCNFFSNTGATFQLKDGALAYARX------XXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSVIEAQYISYHDIKPGAVVKXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVLLCDPEAKRLMMTLKK
TLVESKLPAITCYTSAKP
PF00575 // ENSGT00390000012228_0_Domain_3 (559, 629)
SLQTHGFIFKVKDCGCIVKFYNDVQGLAPKHELST-EYISAP
ETVFYPGQVVKVTVLNCEPARERMLLSF
ENSGT00390000012228_0_Linker_3_4 (629, 750)
KLLQDPQKE----LEGGSRKKGKAVHVGQLVD
VKVVQKAKDGLEVAVLPH--NIPAFLPTPHLSDHVANGPLLYHWLQAGDTLHRVL---CL
Q-SEGRVLVCRKPALVSTAEGGQDPKSFP
PF00575 // ENSGT00390000012228_0_Domain_4 (750, 823)
EIQPGMLLIGFVKSIKDYGVFVQFSSGLSGL
APKAVLSDKFVTSTSDHFVEGQTVVAKVTNVDEEKQRMLLSL
ENSGT00390000012228_0_Linker_4_5 (823, 1075)
RLSDCSLGDGAATSLLLL
SQCLEELQGVRSLMS--SR-DSVLVQTLAEMTPGMVLDLVVLEVLEDGSVVFSGGPVPGL
-VLRASKYHRAGQEVESGQKKKAVILNVDMLKLEVHVSLNHDLVTRK-HKRLKKGSEHQA
TVQHMEESFAIASLAE--TGQLAVFSLTSHLNDTFRFDSEKLQVGQGVSLTLKTTQPGVT
GLLLAVEGPAAKRTMRQAHKESETADEDE-----------EADPALAVGVVKKH
PF00575 // ENSGT00390000012228_0_Domain_5 (1075, 1150)
TLSIGD
VVTGTVKSIKATHV-VTLGDGVIGCIHASHILDDVPAGTTPTSNLKVGKTVTARVIGGRD
VKTFQFLPISHPRFIRTIPELSVRTSELE------GGHTALNTHSVSPSEKIKQYQVGQT
VTCFLKRYNVVKKWLEVEIAPDIRGRIPLLLTSLSFKXXXXXXX-XXRLGQA-LRATVVG
PD-SAKAFLCLSL-IGPHKLEKGEVAMGRVVKVTPNEGVMVSFPFGKFGRASLFHLSDNY
SEMPLENFVPQNIVRCYVLSSADHVLTLS---LRSSXXXXXXXXXXXXXXXXXXXXXXXX
QLLRGYVKAVE-PKGVLLSLGPSVVGLAQYSHVSQYCPSKKALYSRHLPQGRLLTAKVLS
----------------LNHKKNLVALSFLPKDTGKPDVLPASVELPLLEQEKGTET-EGA
DRKTTEKKTRRRE-------------------EIQRK---------EVQRKRQPQV--KK
PGKRGRGEAE------SQQESVNKKPKRAAPSEED----DSGVEVYYREGEDE-VEEMAL
------------------------------PRQEKPARLADVPRLQRSSGFMWDVGLDSW
TP-GLPPRDS-SDSEDDE-KPSEATK---KSKKERALTKQKAEKELSRIEEALMDPGRQP
ESADDFDRLVLSSPSSSILWLQYMAFHLQATEIEKARAVAERALKTISFRE-EQEKLNVW
VALLNLENMYGSQESLTKVFERAVQYNEPLKVYLHLADIYTKSDKFQEAGELYGRMLKRF
RLEKAVWIKYGSFILRRGQAGSSHRVLQRALECLPQKEHVDVITKFAQLEFQLGDAERAK
AIFENTLSTYPKRTDVWSVYIDMTIKHGSQKEV---------------------------
---------------------------------
ENSMOCP00000025801 (view gene)
-MANLEENFPRGGTRK--SHKSEKPSQQAVEQDNLFDIS---TEEESTKRK-KSQKGPMK
T----KKLKTEKREAKKSLREKFEILSVESLCEGMRILGCVKEVNELELVISLPNGLQGF
VQVTEICDAYTQKLNEQVAQEEPLEDLLRLPDLFSPGMLVRCVVSSLDITDRGKKTVKLS
VNPKHVNKVLSAEALRPGMLLTGTVSSLEDHGYLVDIGVVGTRAFLSLQ--------KNK
GAKLKIGQYLTCLVEEVKSNGGIVSLSVEHSEISSAFATEEQSWNLNNLLPGLVVKAQVQ
KVTQFGLQLNFLTFFTGLVDFMHLEPKKIGAYSSAQTVKACILCIHPRTRVVRLSLRPIF
LQPGRPLTRISFQKIGAVLDNVPVQGFFEKAGATFKLRDGTLAYARL------SHLSDSK
KLFSAEAFKPGSTHKCRIIDYSQMDELALLSLRKSVITAQFLRYHDIT
PF00575 // ENSGT00390000012228_0_Domain_1 (469, 539)
SGTVIKGTVLAI
KAFGILVKVGEQMRGLVPSMHLADIMMKNPEKKYHLGDEVKCRVLHCDPEAKKLIMTLKK
TLVTSKLPAITCYEDAKPGLQTHGVIIRVKSYGCIVKFYNNVQGLVPKHELSE-QHIPDP
ERVFYTGQVVKVAVLNCEPSKERMLLSFKLLSDSEPKNE--SVESSQKKGRAVNIGQLVD
VKVLEKTKDGLEVAVLPH--NIPAFLPTPHLSDHVANGPLLHHWLQAGDTLHRVL---CL
SQGEKHVLLCRKPALVSTVEGGQDPKSLSEI
PF00575 // ENSGT00390000012228_0_Domain_4 (752, 823)
QPGMLLLGFVKSIKDYGVFVQFPSGLNGL
APKAIMSDKFVTTPSDHFVVGQTVVAKVTNVDEEKQRMLLSL
ENSGT00390000012228_0_Linker_4_5 (823, 1077)
RLSDCSLGNSANTSFILL
CQCLEELQGVRSLMS--NQ-DSVLIQTLAEMTPGMVLDVMVQKVLEDGSVVFSGGPVPDL
-ILKASRYHRAGQEVESGQKRKVVVLHVDMLKVEVHVSLHQDLVNRK-ARKLRKNSRHQG
IVQHLEESFAVASLME--TGQLVAFSLISHLNDTFHFDSEKLHVGQGVCLTLKTTEPGVT
GLILAVEGPASKRTQSPAQRDSETVDGKEE---------EEEDTDLTVRNKKKHGL
PF00575 // ENSGT00390000012228_0_Domain_5 (1077, 1142)
AIGD
KVTGTIKSVKATHVVVTLEDGVIGCIHASRILDDVPVGTSPTTTLKVGETVTARVIGGRD
VKTSKFLPISHPRFVLTILELSIRPSDLK-----KDDYNALNTQSVSPMEKTLQYQAGQT
VTCFFKKYNVIKKWLEVDVAPDIRGRIPLLLTSLSFKVLKHPDK-KFQIGQA-LKATVVS
SD-IPKAFLCLSL-IGPYKLEQGEIAMGRVLSVAPNKGLTICFPFGKIGKVSLFHVSDSY
SEAPLEDFFPQKIVRCYVLSTEHSVLALS---LRSSRANREAKSKIEDPEINSIQDVKEG
QLLRGYVKTVL-SDGVLVSLGPSVVGLAQYSHVSQCSPPRKELYDHYLPKGKLVTAKILR
----------------VNPEKSQVKLSLLPSDTGKPDVFSASPEPPLLNQKERKEGAEER
ALKGEEKEQKSQK---R--KEKNQKGQE--ETEMFSQ---------EKKEPQKSQRS--R
QGKRERQEPA------SELERVSKRPKQSGAPEED----DSGVEVYYREGEDE-MEQLGV
------------------------------LLRGKQAEPAEVPRLQLSSGFIWDVGLDSL
TP-ALPLRGESSDSEED-EKPQQAKK--KKGKKERELEKQKAEKELSRIEEALMDPGRQP
ESADDFDRLVLSSPDSSILWLQYMAFHLQATEIEKARAVAERALKTISFRE-EQEKLNVW
VALLNLENMYGSQESLTKVFERAVQYNEPLKVFLHLADIYTKSEKFKEAGELYSRMLKRF
RQEKA
PF05843 // ENSGT00390000012228_0_Domain_7 (1866, 2006)
VWIKYGAFVLRRSQPGASHRVLQRALECLPTKEHVDVITKFAQLEFQLGDAERAK
AIFENTLSTYPKRTDVWSVYIDMTIKHGSQKEV-REIFERVIHLSLAPKKMKFFFKRYLD
YEKQHGTEKDVQAVKAKALDYVEAKSSALED--
ENSSHAP00000021555 (view gene)
-MASQEDSFPRGGSKKKAHPE--KTPQQPIEHDNLFDVP---TEEGSRKRK-RNQEQGAK
N----KKSKAEKKESSRPEAEACGILSIEALTEGMRLLGCVKEINNLELVISLPNGLWGY
VQATNISDAYTKKLSEQLDQEEPLEDLAPLSELFPPGLLVRCVVSSITSASK-KKSVKLS
LNPKDVNRVLSPAS
PF00575 // ENSGT00390000012228_0_Domain_0 (195, 268)
LKPGMLLTGTVHSVEDHGYLVDIGVMGTKAFLPWQKEQEYVKQKNK
GTKLRVGQYLNCLIEEVKGNGGSVLLS
ENSGT00390000012228_0_Linker_0_1 (268, 468)
TIQSVVSAAIATEEQNWTLDNLLPGLVVKAQVQ
KVTPHGLTLSFFSSFTGLVDFMHLDSKKAGHYFQTQMVRACILSVHPRTKCVRLTLRSSF
LQAGRPITRLCHNLIGAVLNDVPVQGFFAKAGATFRLKDGSLAYARI------MHLSQTE
KSFKPEKFKPGNMHKCRVIDYSPMDDLALLSLKTSIIEAPFLRYHDL
PF00575 // ENSGT00390000012228_0_Domain_1 (468, 539)
HPGQVVKAKVFAL
RSYGMIVKVTEQIKGLVPTLHLADVQIRNPQKKYRLQDEVKCRVLTCDPENKKLLMTLKK
TLVESNLPALTSYKQAKPELQTHGFISSIKDSGCVVKFYNDVRGLVPQRELGA-QPISTP
GEVFYVGQVVKVTVLNSEPEQERMLLSFRLLSDKETEGPAQS-----QKKATIKVGQLVD
VKVKKKTEKGLEVSILPN--NIRALLPTTHLSDSVNNSQLLYSWLRAGDVLHRVL---CL
SHSDGHIILCRKPALISAVESGQDPKVFSE
PF00575 // ENSGT00390000012228_0_Domain_4 (751, 823)
FQPGMLLTGFVKTIKAYGVFVQFPSGLSGL
APKSALSDKFVTTVSDHFVEGQTVVAKVTNVYEEKERMLLSL
ENSGT00390000012228_0_Linker_4_5 (823, 1077)
RLSDVCQEDTAVSSLALL
SQWLEELQGVRSLMS--SRD-SMLTQTLAEITPGLLMDLVVQDMSSDGSLMFSSGSVPGL
-VLKASRYHQGGKVMDPGQRTKAVVLHVDTLKSEVHVSLRQELVNRK-SKQLKKNTEHRA
VIEHLEKTFAIGSLME--TGQLVAFPVTSHLNDTFRFDSEKLQVGQRVSLIIKSAKPSDI
GLFLAVESSVKKRTPALPLADPEPAGEE---------------PGVMSSLLEKPTL
PF00575 // ENSGT00390000012228_0_Domain_5 (1077, 1137)
PIGE
MVTGTVKSVKATHVVVTLENGLVGCIHASQILDDVPLGTQPTAKLKVGKPVTARVIGQRT
LLTHKTLPISHPSSAQTVSELSIRSSLCGNSELEKDISIDPSTHCSSPTEKLKQYLPGQT
VICFMRKFNVIKKWLEVEITPDIRGRIPQLLTSLSFKVLKHPEK-KFKIGQA-LSATVVG
PESSKG-FLTLSL-IGPHRLEEGEVAMGRVVKVIPKEGLQVLFPFGTIGKVSIFHLSDSY
LEAPLEGFHPEKIVRCCVLSTKDPVLTLS---LRQSRTNPRMKNKIEDPEVNSIKNIKEG
QHLRGYVEAVK-KLGVHFRIGPTLVGRVKYRHVTKYFLSDKTLYRTYLPEGKLLSAKVLR
----------------LNRKQKLVYLSFLPKDTGKPDVFPDSLGLPLRDQGKNRVKEVPS
SQPK------KKRKLEG--KEEEDKGDSSTKQ--------EEEKQQESEAKARRAEKAAN
TGKRKMPEMERE----Q--EKVTKKKRPNLLPEED----DSGVEVNYNEEKRL-----KQ
P-------------------------------KQKQTKPTEIPRLQLSSGFVWDVSLDML
AP-AAPPREESSDSEEESS-SQATLK--KKSKKDKELEKQQAEKELTRIETALMDPNWQP
ETADDFDRLVLSSPNSSILWLRYMAFHLHATEIEKARAVAERALKSISFRE-EQEKLNVW
VALMNLENMYGSKETLSKVFERAVQYCEPLKVFFQLADIYSKSEKYQAAEEVYNQMLKRF
RQEKTVWVKYGSFLLQRGKAEACHDLLPRAFSCLPQKEHVDVIS
PF05843 // ENSGT00390000012228_0_Domain_7 (1905, 2008)
KFAQLEFYQGDGERGK
AMFESTLNSYPKRTDVWSIYIDMLIKFGSQKEV-RDAFERVVHLSLSPKRMKFFFKRYLD
YEKQHGTAETVQAVKEKALNYVESRNTLADS--
ENSJJAP00000012542 (view gene)
-MATLEESFPRGGAKK--THKSEKSSQQAVEQDNLFDIS---PEEESIKRKKKIQKGPAK
T----KKLKLEKTETIKSLKEKLEILTVESLCEGMRILGCVKEVNELELAISLPNGLQGF
VQVTEICDAYTKQLNEQVAQEEPLKDLPSLPELFFPGMLVRCVVSSVGITERGKKIIKLS
LNPRNVNKVLSAEAL
PF00575 // ENSGT00390000012228_0_Domain_0 (196, 267)
KPGMLLTGTVSSLEDHGYLVDIGIGGTRAFLPVQKAQEGIRQKNR
GAKLKVGQYLTCLVEEVKSNGAVVSL
ENSGT00390000012228_0_Linker_0_1 (267, 468)
SAGHSDISSAFATEDQSWTLNNLLPGLVVKAQVQ
KVTPFGLKLNFLTFFTGLVDFMHLEPKKIGTYSPNQTVRACVLCIHPRTRAVRLSLRPVF
LQPGRPLTRLSCQHLGAVLDDVPVQGFFRNAGVTFRLKDGALAYVRL------SHLSDSK
KSCNPEAFTPGSTHKCRIIDYSQMDELALLSLRRSVIEAQFLRYHDI
PF00575 // ENSGT00390000012228_0_Domain_1 (468, 539)
NIGAVVKGTVLTV
KPFGILVKVGEQMRGLVPPMHLADVLMKNPEKKYHAGDEVKCRVLLCDPEAKKLVMTLKN
TLVTSKLPAITCYEDAKAGLQTHGVIVKVKDYGCIVKFYNDVQGLVPRHELSA-QYIPDP
EKVFYTGQVVKVTVLNCEPSKERMLLSFRLLNDPEPQNE--SIGHAQKKGRVINIGQLVD
VKVIEKTKDGLQVAVLPH--NIPAFLPTPHLSDHVANGPLLHHWLQAGDTLHRVL---CL
SQSEKHVLLCRKPALVSTVEGGQDPKSFSEIQP
PF00575 // ENSGT00390000012228_0_Domain_4 (754, 823)
GMLLIGFVKNIKDYGVFVQFPSGLSGL
APKAIMSDKFVTTPSDHFVEGQTVVAKVTNVDEEKQRMLLSL
ENSGT00390000012228_0_Linker_4_5 (823, 1078)
RLSDCHLGTSASTSLLLL
SQCLEELQGVRSLMS--SR-DSVLIQTLAEMTPGMVLDLTVKEVLGDGSVVFSGGPVPDL
-VLRASRYHREGQEVESGQKRKVVILNVDMLKLEVHVSLRQELVNRK-AKKLRKGSEHKA
TVQHLEESFAVASLVE--TGHLVAFSLTSHLNDTFRFDSEKLQVGQGVSLTLKTTEPGVT
GLLLAVEGPAAKRTMRTARRDSETADDNED-----------EDAALVVGSKKKHTLT
PF00575 // ENSGT00390000012228_0_Domain_5 (1078, 1143)
LGD
MVTGTVKSVKATHVVVTLEDGIVGCIHASNVLDDVPVGTSPTSTLKVGKTVTARVIGGRD
VKTYKFLPISHPRFIQTILELSVRPSELE-----G-SHTALDTYSVSPVEKIKQYQAGQT
VTCFLKKYNVIKKWLEVDVAPDVRGRIPLLLTSLSFKVLKHPDK-KFQIGQA-LRATVVG
PD-SRKAFLCLSL-IGPHKLEPGEVAMGRVVKVTPNEGLTVSFPFGKVGTVSVFHISDSY
SEAPLEDFVSQKVVRCYVLSAAGDTLTLS---LRSSRTNPETKSKIEDPEINSVQDIKEG
QLLRGYVRSVQ-QSGVLLGLGPSVVGWAQHSHVSQSSTPKKELYHHYLPEGRLLTAKILR
----------------VNHQKNLVELSLLPGDTGKPDVFSASPELPLGKPEARRGEAEER
DQKGEEKK----K---R--KRKDQKGQR--EVKLPSQ----------KKEPQGSRGK--K
PGKRECQERA------REQEIVNKRPKEACVPEED----DSGVEVYYREGEDE-LEEPKV
------------------------------LPKGGLTKPAEVPRLQLSSGFLWDVGLDSL
TP-ALPPRGESSDSEED-EQPQQATQ--KKSKKEKELEKQKAEKELSRIEEALMDPGRQP
ESADDFDRLVLSSPNSSILWLQYMAFHLQATEIEKARAVAERALKTISFRE-EQEKLNVW
VALLNLENMYGSQESLTKVFERAVQYNEPLKVFLQLADIYTKSEKFKEAGELYNRMLKRF
RQEKT
PF05843 // ENSGT00390000012228_0_Domain_7 (1866, 2008)
VWIKYGAFVLRRNQPGASHRVLQRALECLPTKEHVDVIAKFAQLEFQLGDAERAK
AIFENMLSTYPKRTDVWSVYIDMTIKHSSQKEV-RDIFERVIHLSLAPKRMKFFFKRYLD
YEKQHGTEKDVQAVKAKALEYVEAKSSVLED--
ENSOANP00000029495 (view gene)
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VVQHLEKEFVIASLVE--TGQLVAFPIASHFNDTFRFDSEKLQLGQGVCLTLRTTEPGDF
GLLLATKEPASKRVVPKPQEKLEPTGEPQEKVGPTR--KPQKKVGPTREAVKKHAFS
PF00575 // ENSGT00390000012228_0_Domain_5 (1078, 1140)
IGE
LVKGIVRSVKPTYIIVTLESGITGFIHVSQILDEVPLGTCPTTRLKAKKRITARVIGGKD
MRTRRFLPATHSRFIRTVPELSIRPR----------------------------------
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ENSOGAP00000007792 (view gene)
-MATLEESFPRGGTRK--THKSEKALQKSVEQDNLFDIS---TEEKSTKRK-KGQKEPAK
T----KTLKIKKRESIKSVREKFDILSVESLCEGMRILGCVKEVNELELVISLPNGLRGF
VQVTEICDAYTKKLNEQVTQEEPLKDLLHLPELFSPGMLVRCVVSSVDTTERGKKSVKLS
LNPKNVNRVLSAES
PF00575 // ENSGT00390000012228_0_Domain_0 (195, 268)
LKPGMLLTGTVSSLEDHGYLVDIGVDGTRAFLPLPKAQEYIRQKNK
GAKLKVGQYLNCVIEEVKASGGVVSLA
ENSGT00390000012228_0_Linker_0_1 (268, 469)
IGHAEVSTAITTEEQNWTLNNLLPGLVVKAQVQ
KVTPHGLTLNFLTFFTGLVDFMHLDPKKAGTYFSNQAVRACILCVHPRTRVVRLSLRPIL
LQPGRPLIRLSCQHLGAVLDDVSVQGFFNKAGATFRLKDGTLAYARL------SHLSDSE
NSFNPDAFKPGNTHKCRIIDYSQMDELALLSLRTAIIEAQYLRYHDIK
PF00575 // ENSGT00390000012228_0_Domain_1 (469, 539)
PAAVVKGTVLTI
KPYGMLVKVGEQIRGLVPAMHLADIPIKNPEKKYHVGDEVKCRVLLCDPEAKKLMMTLKK
TLVESKLRAIACYSDVKPGLQTHGFIIRVKDYGCIVKFYNDVQGLVPKHELSA-EYIPDP
ERVFYTGQVVKAVVLNCEPSKERMLLSFKLLSDPELQKE--PTGHSRKKGRVINIGQLVD
VRISEKTKDGLEVTVLPS--NIPAFLPTPHLSDHVANSPLLYHWLQPGDTLHRVL---CL
SRSEGHVLLCRKPALVSTVEGGQDPKNFSEIH
PF00575 // ENSGT00390000012228_0_Domain_4 (753, 823)
PGMLLIGFVKSIKDYGVFVQFPSGLSGL
APKAIMSDKFVTSTSDHFVEGQTVVAKVTNVDEEKQRMLLSL
ENSGT00390000012228_0_Linker_4_5 (823, 1078)
RLSDCMLGDAATTSLLLL
NQCLEELQGVRSLMR--NR-DSILIQTLAEMTPGMILELVVQEVLEDGSVVFSGGPVPGL
-VLRASKYHRAGQEVESGQKKKVVVLNVDMLKLEVYVSLHQDLVNKK-AKKLKKGSEHQA
IVQHLEESFAVASLVD--TGHLAAFSLTSHLNDTFRFDSEKLQVGQGVSLTLKTTEPGVT
GLLLAVEGPAAKRTMRRTQKDSETVDEDE-----------EVDPALAIATIKKHALS
PF00575 // ENSGT00390000012228_0_Domain_5 (1078, 1139)
IGD
MVTGTVKSIKPTHVVVTLEDGIIGCIHASHILDDVPEGTCPTAKLQVGKTVTARVIGGRD
VKTFKFLPVSHPRFVRTIPELSVRPSELE------DGHTALNSHSVSPMEKIKQYQAGQT
VTCFLKKYNVVKKWLEVEIAPDVRGRIPLLLTSLSFKVLKHPDK-KFRIGQA-LSATVVG
PD-SSKAFVCLSL-IGPHKLEKGEVAMGRVAKVTPNEGLMVSFPFGKMGRVSVFHVSDSY
SEMPLEDFIPQKVVRCYVLSTEDEVLTLS---LRSSKTNPETKSRVEDPEINSIHDVKKG
QLLRGYVKSIE-PQGVLFGLGPSVVGLAQYSKVSQYSLFKKALYNKYLPEGRLLTAKILS
----------------VNHQKNLVELSFLPSDTGKPDVFPASPELPLSKQEERKIEAEER
DQKGEEKNQKRK-----D-K-KNQKGQEE--AELPSK---------EKTQGKRRRQT-SV
RGQSWAFSYL------SPQETVNKKAKKAGL-SED----DSGVEVYYREGEEE-IEETNV
------------------------------LPKKQQTRPAEAPRLQLSSGFAWNVGLDSL
TP-ALPPRAESSDSEEDE-NPHQAVK--KRSKKEKELEKQKAEKELSRIEEALMDPRRPP
ESADDFDRLVLSSPNSSILWLQYMAFHLQATEIEKARAVAERALKTISFRE-EQEKLNVW
VALLNLENMYGSQESLTKVFERAVQYNEPLKVYLHLADIYAKSEKFQEAGELYNRMLKRF
RQEKA
PF05843 // ENSGT00390000012228_0_Domain_7 (1866, 2008)
VWIKYGAFLLRRSQAGASHRVLQRALECLPRKEHIDVIAKFAQLEFQLGDAERAK
AIFENMLSIYPKRTDVWSVYIDMTIKHCSQKEV-RDIFERVIHLSLAPKRMKFFFKRYLD
YEKQHGTEKDVQAVKAKALEYVEAKSSVLEE--
ENSSSCP00000034692 (view gene)
-MATMEESFPRGGTRKIRKSE--KTLQQSVEQDNLFDIS---TEEESTKRK-KSQKEPAT
I----KKLKTDKRESSKFVREKFEILNEESLCEGMRILGCVKEVNELELVISLPNGLQGC
VQVTEICDAYTKKLNEQVAQEEPLQDLVGLPELFSPGMLVRCVVSSLGITKSGKKDVKLS
LNPKNVNKVLNPEAL
PF00575 // ENSGT00390000012228_0_Domain_0 (196, 268)
KPGMLLTGTVSSLEDHGYLVDIGVSGARAFLPLQKAQEYIRQKNK
DAKLKVGQYLNCIIQEVKGSGGVVSLS
ENSGT00390000012228_0_Linker_0_1 (268, 468)
IGNSEVSAAIATEEQNWTLNNLLPGLVVKAQVQ
KVTPLGLTLKFLSFFTGLVDFMHLDPKKAGTYFSNQPVRACVLCVHPRTRDVRLSLRPTF
LQPGRPLTGLSCQQLGAVLEDVPVQGFFGNAGATFRLKDGTLAYARF------NHLSNSK
KAFKPETFKPGNIHKCRIIDYSRMDEMVLLSLRTSVIEAQFLRYHDI
PF00575 // ENSGT00390000012228_0_Domain_1 (468, 538)
KPGALVKGKVLTI
KPYGMLVNMGREIRGLVPPMHLADILMKNPEKKYHVGDEVKCRVLLCDPEAKRLMMTLKK
TLVESKLPAITCYADAKPGLQTHGFILRVKDYGCIVKFYNDVQGLVPKHELSA-EYVPDP
ESVFYAGQVVKVVVLNCEPSKEKMLLSFRLSSDPK--KE--SEGHSQKKKRALTAGQLVD
VKVLDKTKDGLEVAVLPH--NIRAFLPTPHLSDHVANSPLLYHWLQAGDVLHRVL---CL
SETEGRVLLCRKPALVSAVEGGQDPKSFSEIHPGMLLI
PF00575 // ENSGT00390000012228_0_Domain_4 (759, 823)
GFVRSIKDYGVFIQFPSGLSGL
APKAIMSDKFVTSTSDHFVEGQTVVAKVTNVDEEKQRMLLSL
ENSGT00390000012228_0_Linker_4_5 (823, 1077)
RLSDCTLGDQATTSLLLL
SQCLEEQQGVRSLMS--NR-DSVLIQTLAEMTPGMVLDLEVQEVLEDGSVLFSEGPVPGL
-VLRASKYHRAGQEVESGQKKKVVILNVDMLKLEVHVSLRRDLVNRR-TKKLRKGGEYQA
VVQHLEETFAVASLVE--TGHLAAFSLTSHLNDTFRFDSEKLQVGQGVSLTLSTTEPGVT
GLLLAVEGPAAKRTMRQTRKDSETVDEDE-----------EVDPALVVGTVKKHTL
PF00575 // ENSGT00390000012228_0_Domain_5 (1077, 1139)
SIGD
MVTGTVKSIKPTHVVVTLEDGIVGCIHASHILDDVPVGTSPTTKLKVGKKVTARVIGGRD
MKTFKFLPISHPRFIRTIPELSVRPSELK-----EDGHTALNTHSVSPLEKIKQYKAGQT
VTCFLKKYNVVKKWLEVEIAPDIRGRIPLLLMSLSFKVLKHPDK-KFQIGQA-LKATVVG
PD-SSKAFLCLSL-IGPHKMEKGEVAMGRVVKVTPKEGLMVSFPFGKIGKVNIFHVSDSF
SETPLEDFTPQKIVRCYVLSNAGPVLTLS---LRSSRTNPDTKSKIVDPEINSTQDIEEG
QLLRGYVKSIQ-PSGVLLGLGPSVTGLARYSHVSQHSPTRNALYDKYLPEGKLLTAKVLS
----------------LNRRENLVELSFLPGDTGKPDVFSASPRLPHLKQEGRDTEAEER
EHKGEGETEE--RKRQKRKEKSSGKEQE--EAPLPSR---------ETKEPQRPRAK--K
PGKRPHPESA------SEQESVNKKQKKAALSEEE----DSGVEVYYREGEEE-VEETGM
------------------------------RPKEKQTRLAEAPRLQLSSGFTWDVGLDSL
TP-ALPPHGESSDSEEDE-KPEQAT-KK-KSKKERELEKQKAEKELSRLEEALMDPGRQP
ESADDFDRLVLSSPNSSILWLQYMAFHLQATEIEKARAVAERALKTISFRE-EQEKLNVW
VALLNLENMYGSQESLTKVFERAVQYNEPLKVFLHLADIYTKSEKFQEAGELYNRMLKRF
RQEKA
PF05843 // ENSGT00390000012228_0_Domain_7 (1866, 2009)
VWIKYGAFLLRRGQAGASHRVMQRALECLPKKEHVDVIAKFAQLEFQLGDAERAK
AIFENTLSTYPKRTDVWSVYIDMIIKHGSQKEV-RDIFERVIHLSLAPKRMKFFFKRYLD
YEKQHGTEKDVQAVKAKALEYVEAKSSLEED--
ENSMPUP00000016724 (view gene)
----MEESFPRGGTRKTHKSE--KALQKSVEQDNLFDLS---TEEESTKRK-KSQKGPAK
T----KKLKTEKRESSKSIREKFEILNIESLCEGMRILGCVKEVNELELVISLPNGLRGF
VQVTEICDAYTKKLNEQVAQEEPVKDLVGLPELFSPGMLVRCVVSSVGITERGKKSVKLS
LNPRNVNEVLSAEAL
PF00575 // ENSGT00390000012228_0_Domain_0 (196, 262)
KPGMLLTGTVSSLEDHGYVVDIGVSGARAFLPLQKAQEYIRQKNK
GAKLKVGQYLHCIIEEVKGNGGVVGLSIGHSEVSAAIATEEQNWTLNNLLPGLVVKAQVQ
KVTPVGLTLNFLSFFTGLVDFMHLDPKKAGTYFSNQAVRACVLCVHPRTRAVRLSLRPVF
LQPGRSLTRLSCQHLGAVLDDVPVQSFISKAGATFRLKDGALAYARL------SHLSDSK
NVFSADSFKPGNTHKCRIIDYSQMDELALLSLRTSIIEAQYLRYHDIKPGALVEGTVLTI
KPYGMLVKVGEQIRGLIPPMHLADILMKNPEKKYHIGDEVKCRVLLCDPEAKKLMMTLKK
TLIESKLPAITSYADAKPGLQTH
PF00575 // ENSGT00390000012228_0_Domain_3 (564, 628)
GFILRVKDYGCIVKFYNDVQGLVPKHELSA-EYVPDP
ERVFYAGQVVKVVVLNCEPSKERMLLS
ENSGT00390000012228_0_Linker_3_4 (628, 753)
FKLLSDPK--KE--HLGHSQKKRRTVSLGQLVD
VKVLEKTKDGLEVAVLPY--NTPAFLPTPHLSDHVANGPLLYHWLQTGDTLHRVL---CL
SQSEGRVLLCRKPALVSTVEGGQDPKSFAEIH
PF00575 // ENSGT00390000012228_0_Domain_4 (753, 823)
PGMLLIGFVKSIKDYGVFVQFPSGLSGL
APKAIMSDKFVTSTSDHFVEGQTVVAKVTNVDEEKQRMLLSL
ENSGT00390000012228_0_Linker_4_5 (823, 1078)
RLSDCGLGDLATTSLLLL
SQCLEERQGVRSLMS--NR-DSVLIQTLAEMTPGMVLDLEVQEVLEDGSVVFSEGPVPGL
-VLRASRYHRAGQEVEPGQKKKVVILNVDMLKLEVHVSLCHDLVNRR-AKKLKKGSEYQA
VVQHLEESFAVASLVE--TGHLAAFSLTSHLNDTFRFDSEKLQVGQGVSLTLKTTEPGVT
GFLLAVEGPAAKRTVRQTRKDSETVDEDE-----------EADPALVVGTVKKHTLS
PF00575 // ENSGT00390000012228_0_Domain_5 (1078, 1138)
IGD
MVKGTVKSVKPTHVVVTLEDGIIGCIHASHILDDVPLGTSPTAKLKVGKTITARVIGGRD
MKTFKFLPISHPRFIRTIPELSIRPSELE-----KDGCTALNTHSVSPSEKVKQYQAGQT
LICFLKKYNVVKKWLEVEIAPDIRGRIPLLLTSLSFKVLKHPDK-KFRIGQA-LKATVVG
PD-SSKAFLCLSL-IGPHKLEKGEVAMGRVVKVTPKEGLTVSFPFGKIGRVSVFHLSDSY
SETPLEDFVPQKVVRCYVLATTGHVLTLS---LRSSRTNPKTKSKITDPEINSIQDIQEG
QLLRGYVKSVQ-PHGVLFRLGPSVVGLARYPYVSQYSPSDKALYHKHLPEGKLLTAKVLS
----------------LNREKNLVELSFLPDDTGKPDVFPASLGLPLLKQEEREREAAEK
EHKGEEEK----KKNQKRKRKRNQEGPE--EAQPSSQ---------EKSEAQKPQAE--K
RGRRRRRESA------SEQERVNKKQKKVAPSEED----DSGVEVYYREGEEE-VEEMSV
------------------------------LPKGKPTRPAEAPRLQLSSGFVWDVGLDSL
TP-ALPPRGDSSDSEEDD-EPQQATQ-K-KSKKERLLEKQKAEKELSRIEEALMDPGRQP
ESADDFDRLLLSSPNSSILWLQYMAFHLQATEIEKARAVAERALKTISFRE-EQEKLNVW
VALLNLENMYGSQESLTKVFERAVQYNEPLKVFLHLADIYAKSEKFQEAGELYNRMLKRF
RQEKA
PF05843 // ENSGT00390000012228_0_Domain_7 (1866, 2007)
VWIKYGAFLLRRGQAGASHRVMQRALECLPIKEHVDVIAKFAQLEFQLGDAERAK
AIFENTLSTYPKRTDVWSVYIDMTIKHGSQKEV-RDIFERVIHLSLAPKRMKFFFKRYLD
YEKQHGTEKDVQAVKAKALEYVEAKSAMLED--
ENSRROP00000012353 (view gene)
-MATLEESFPRGGTRK--IHKPEKAFQQSVEQDNLFDIS---TEEGSTKRK-KSQKGPAK
T----KKLKIEKRESSKSAREKFEILSVESLCEGMRILGCVKEVNELELVISLPNGLQGF
VQVTEICDAYTKKLNEQVTQEQPLKDLLHLPELFSPGMLVRCVVSSLGITDRGKKSVKLS
LNPKNVNRVLSAEALKPGMLLTGTVSSLEDHGYLVDIGVDGTRAFLPLLKAQEYIRQKNK
GAKLKVGQYLNCIVEKVKGNGGVVSLSVGHSEVSTAIATEEQSWTLNNLLPGLVVKAQVQ
KVTPFGLTLNFLTFFTGVVDFMHLDPKKAGTYFSNQAVRACILCVHPRTRVVRLSLRPMF
LQPGRPLTRLSCQNLGAVLDDVPVQGFFKKAGATFRLKDGILAYARL------SHLSDSK
NVFNPEAFKPGNTHKCRIIDYSQMDELALLSLRTSIIEAQYLRYHDI
PF00575 // ENSGT00390000012228_0_Domain_1 (468, 538)
EPGAVVKGIVLTI
KSYGMLVKVGEQMRGLVPPMHLADILMKNPEKKYHIGDEVKCRVLLCDPEAKKLMMTLKK
TLVASKLPVITCYADAKPGLQTHGFIIRVKDYGCIVKFYNNVQGLVPKHELST-EYIPDP
ERVFYTGQVVKVAVLNCEPSKERMLLSFKLSSDPEPKKE--PAGHSQKKGKAVNIGQLVD
VKVLEKTKDGLEVAVLPH--NIHAFLPTSHLSDHVANGPLLHHWLQAGDILHRVL---CL
SQSEGHVLLCRKPTLVSTVEGGQDPKNFSEIHPGMLLI
PF00575 // ENSGT00390000012228_0_Domain_4 (759, 823)
GFVKSIKDYGVFIQFPSGLSGL
APKAIMSDKFVTSTSDHFVEGQTVAAKVTNVDEEKQRMLLSL
ENSGT00390000012228_0_Linker_4_5 (823, 1077)
RLSDCALGDLATTSLLLL
SQCLEELQGVRSLMS--NR-DSVLIRTLAEMTPGMFLDLVVQEVLEDGSVVFSGGPVPDL
-VLRASRYHRAGQEVESGQKKKVVILNVDLLKLEVHVSLHQDLVNRK-AKKLRKGSEHQA
IVQHLEKSFAVASLVE--TGHLAAFSLTSHLNDTFRFDSEKLQVGQGVSLTLKTTEPGVT
GLLLAVEGPAAKRTMRPTRKDSETVDEDE-----------EVDPALTVGTIKKHTL
PF00575 // ENSGT00390000012228_0_Domain_5 (1077, 1139)
SIGD
MVTGTVKSIKPTHVVVTLEDGIIGCIHASHILDDVPEGISPTTKLKVGKTVTARVIGGRD
MKTFKFLPISHPRFVRTIPELSVRPSELE------DGHTALNTHSVSPVEKIKQYQAGQT
VTCFLKKYNVVKKWLEVEIAPDIRGRIPLLLTSLSFKVLKHPDK-KFRVGQA-LRATVVG
PD-SSKAFLCLSL-IGPHKLEEGEVAMGRVVKVTPNEGLTVSFPFGKIGTVSIFHVSDSY
SEMPLEDFVPQKVVRCYVLSTTDSILTLS---LRSSRTNPETKSKVEDPEINSIQDIKEG
QLLRGYVGSIQ-PHGVFFRLGPSVVGLARYSHVSQHSPSKKALYNKHLPEGKLLTARVLR
----------------LNHQKNQVELSFLPGDTGKPDLLSASLEGPLPKQEERKTEAEER
DQKGEKKNQKKN-----E-K-KNQKGQEE--VELPSK---------EKQQPQKPQAQ--K
RGGRERRESG------SEQERVSKKPKKAGPSAED----DSLMDVYYREGKEE-AEETNV
------------------------------LPKEKQTKPAEVPRLQLSSGFAWNVGLDSL
TP-ALPPLAESSDSEEDE-KPHQATK--KKSKKERELEKQKAEKELSRIEEALMDPGRQP
ESADDFDRLVLSSPNSSILWLQYMAFHLQATEIEKARAVAERALKTISFRE-EQEKLNVW
VALLNLENMYGSQESLTKVFERAVQYNEPLKVFLHLADIYAKSEKFQEAGELYNRMLKRF
RQEKA
PF05843 // ENSGT00390000012228_0_Domain_7 (1866, 2008)
VWIKYGAFLLRRSQAGASRRVLQRALECLPSKEHVDVIAKFAQLEFQLGDAERAK
AIFENTLSTYPKRTDVWSVYIDMTIKHGSQKAV-RDIFERVIHLSLAPKRMKFFFKRYLD
YEKQHGTEKDVQAVKAKALEYVEAKSSVLED--
ENSXETP00000020931 (view gene)
-LGNMEESFPRGGTQKKTDQK-TVKKRPKENDGNLFSTYHEENEQEIKKKK-KVFHEK--
-----PKAASQEKSVTTAAKETVEIPQYKNLSVGMMFLGCVKQAKDFELAVSLPYCLTGY
IQATNICEAYTKLIGEQVKKDDPMEALTPLSELYSPGMLVRCAISSLETTTSGCNSVKLS
INPKHVNKALTTGSLKAGMLVSGCVSSVEDHGYLVDIGVTGSKAFLPRQKAQLFLNQAGK
GPLLRIGQYLNCVIQEVKNEGRIVRLSITQNDVTGALATMEQNWTLNNLLPGLVLKAQIE
KVTQSSITLSFLSSYTGFVDFLHFEPKKIGSYKEGQEVKACILWLDPSTKSIRLTLRQCF
QQPGNPLPQLTSDWVGSVLENCMVQTLVRNAGAIFELDGGNLGFAFK------HNLSASK
H-PDNEIFKKGTAHKGRIKEFSPMEEMHFLSLREKMITDLFLRHEDIQAGQVLEGTIQSL
EAVGLVVKITDHLTGLVPKLHFADVLLKHPEKKYIIGNKIKCKVLTVITSERKLILTRKK
TLMKSKLPIIASFD
PF00575 // ENSGT00390000012228_0_Domain_3 (555, 629)
DAQPGLITHGFIVAIKDYGCIVKFFNEVQGLAPRRELGSLQEISSL
EDAFYRGQVIKVRVLDCNPQTQKLLLSF
ENSGT00390000012228_0_Linker_3_4 (629, 750)
RITEEGETEQE-QR-YLKKTKAVKLDVGKVVD
TRVVSKTDKGVNVLILPE--ESPAFIPKMHLSDHISNCELLWHALEEGDNIPGVM---CL
STFKGHHILTKKAVLISSFEKGSCVKVIS
PF00575 // ENSGT00390000012228_0_Domain_4 (750, 823)
EVQTGMHLTGFVKSIMPYGAFVEFPYGLFGL
VPKSEISDKFVTNISDHLFEGQTVLAKVIKTDEEKQRFLLTL
ENSGT00390000012228_0_Linker_4_5 (823, 1075)
KMSECAPSDCSAEGLLLL
SQCFSELQLLKGLLS--RKGDPEDELSIYTLTSGQKLTLVVENAEENGPVHFSTGSITGA
QTVSATHNNIGDETPIAGQKVKAVVLHVDLLKLHVYVSLNEALLKKK-KNVPKMNSSHSA
DVLHVAEEFAVVSLTG--PAHLAAVPMSSHLNDTFHFESEKLKVGETITVILKATSVNEQ
GLLLAVQNKSALKTSKNQGQ--------------------TKQSDVKTSGFMAH
PF00575 // ENSGT00390000012228_0_Domain_5 (1075, 1145)
GLKVGD
LVSGTVKSIKPTQVIVSINDNVCGFIHVSQITEDTPLGSFPTSKLSPKQEVTGRVIGGRE
VKSHRYLPITHPDFIHSLPELSILPGKWG-----DSFSLINKDNKVPKPRPLKTFTPGEK
VTCYINKYNTEKKYLEVEITPQIRGRIELLLLSQTPKNLKRPEK-LFKNGQS-LSATVVG
PDATHK-HLCLSL-TGIYSLEEGSVTMASVTKVVKGSGLTLSLPFGKTGEASIFHLHDNY
TEASLDKFTPGKIVRCAILSVS-KTIKVS---LMQSKINQQASKSTDDKEITSFDSLEEG
QLVTGFVSAVTQNKGVFFRLSSSIVGHIQFRNITSYFVYDTSAYSKYIPEGTLLTAKVLS
----------------VDPEQKHVELSLLPSDTGKPDVIPESAGFSKRKNKEKKTTT---
KRKR------ENLEKGS----------------QQS-----------------NLLGVC-
----TK---LTK----EGSAYFPQKKKSQESKEDE----DSGVEVYCREEDSEDKTKKTQ
TQQQSQVITCRSLYECNHLDKKDYMAEYHMLLKEQTSSQPSVSRLQVSTGFSWDVSLNTL
KPSLAGANDSSSDSDEEED-EQ-PKK--KKMKKELAREKKEAEKELSKKEAALQDSGRQP
QSADDFDRLVISSPDSSILWLQYMAFHLHATEIEKARVVAERALKTISFRE-EQEKLNVW
VALLNLENMYGTEESLVKAFERAVQYNEPLKVYQQLADIYVKSEKFKQAEDLYNTMLKRF
RQEKSVWIKFATFLLKQGQGDGTHRLLQRALKSLPEKDHVDVISKFAQLEFQLGDSERAK
ALFESTLSSYPKRTDLWSVYIDMMVKHGSQREVSRDIFERVIHLSLAAKRIKFFFKRYLE
YEKKHGSAESVQAVKEKALQYVESQSSLAAT--
ENSODEP00000010837 (view gene)
-MAALEESFPRGGTKR--INKSEKSYQQSVEHDNLFDIS---TEEESAKRK-KNQKGPAK
A----KKLKIEKRERGKSVKEKFEILSIESLCEGMRILGCVKEVNELELVISLPNGLQGF
VQVTEICDAYTKKLNEQVAQDEPLQDLLRLPELFSPGMLVRCVVSSVNITDKGKKSVKLS
VNPRNVNRVLSAEAL
PF00575 // ENSGT00390000012228_0_Domain_0 (196, 268)
KPGMLLTGTVSSLEDHGYLVDIGVGGTRAFLPLQKAQEYIGQKNK
GAKLKVGQYLNCTIQEVKGNGGVVSLS
ENSGT00390000012228_0_Linker_0_1 (268, 468)
IEQSEVSTALATQEQNWTLNNLLPGLVVKAQVQ
KVTQYGLSLSFLTFFTGLVDFMHLDPKKVGTYFTHQTVRACVLCVHPRTRAVRLSLRPLF
LQPGRPLTRLSCPHLGAVLQDVPVQGFFNKAGATFRLKDGALAYARL------GHLSDSK
N-LKLEAFKPGNTHKCRIIDFSQMDELALLSLRTSVIEAQYLKYHDI
PF00575 // ENSGT00390000012228_0_Domain_1 (468, 539)
KTGTVIKGTVLTI
KPFGMLVKVGEQMRGLVPAMHLADIPMKNPEKKYRVGEEVKCRVLFCDPEAKKLIMTLKK
TLVTSRLPIIICYEDAKPGLQTHGTILRVKDYGCIVKFYNDVQGLVPRHELSA-QYIPDP
ENVFYAGQVVKVAVLNCEPAKERMLLSFKLLSDREPKNE--VAGHAQKSEKGVSVGQLVD
VKVLEKTKDGLQVAVLPH--NIPAFLPTPHLSDHVANGPLLYRWLQAGDTLHRVLDGHCL
SFP-EHSLINRKPALVSTVEGGQDPKNFSEV
PF00575 // ENSGT00390000012228_0_Domain_4 (752, 823)
QPGMLLVGFVKSITDYGVFVQFPSALSGL
APKAIMSDKFVTNPSDHFVVGQTVVAKVTRVDEEKQRMLLSL
ENSGT00390000012228_0_Linker_4_5 (823, 1077)
RLSDCRLGAASSSSLLLL
SQCLEELQGVRSLLS--SQ-DSVLVQMLAKITPGTVLDLVVQEVLEDGSVAFSGGPEPTL
-VLRASRYHRAGQDVESGQRKKAIVLHVDMLKLEVHVSLRKELVTRK-ARKLKKGSEHQA
TVQHVEESFAVASLVA--TGHLVAFSVASHLNDTFRFDSEKLQVGQEVCLVLKTTEPGVT
GLLLAVEGPPAKRVLRQTRKDSETVDEEE-----------DGDPALAAEPKKKHTL
PF00575 // ENSGT00390000012228_0_Domain_5 (1077, 1142)
AIGD
TVTGTVKSVKPTHVVVTLEGGVTGCIHASRILDDVPEGITPTATLKVGKRVTARVIGGRD
VKTSKFLPISHPGFIRTIPELSIRPSELQ-----KDGHTALSTYSASLVETMQQYQAGQT
VTCFLKKYNVVKKWLEVDIAPDIRGRIPLLLMSLSFKVLKHPDK-KFHMGQA-LRATVVG
PD-CSKGFLCLSL-IGPHKLEKGEVAMGRVVKVTPNEGLTVAFPFGKTGTVSVFHVSDSY
SETPLEDFMPQKIVRCYVLSAADHVLTLS---LRSSRTNPETKSKVEDPEINSMQDVKEG
QLLRGYVRAIK-PHGVLLGLGPSIVGLAHLSHVSQSVPARKDLYSRYLPEGRLLTAKVLS
ALRCRHFPPSLSTCCRLNHNKNLAELSFLPADTGEPDVLSVSPELVLQKERDKKGM-KKS
---------------Q-ERKEKNLKGEA--GGQLPSK---------EQMKAKRP------
-GKQERQDSGEAQER------VNKRQKRACPLEED----DSGVEVYYREGEEE-IEE---
-------------------------------TKGTLTKPAEVPRLRISSGFLWDVGLDSL
TP-ALPPRGESSDSEEEE-TPRQATK--KKSKKEREMEKQKAERELSRVEEALMDPGRQP
ESADDFDRLVLSSPDSSILWLQYMAFHLQATEIEKARAVAERALKTISFRE-EQEKLNVW
VALLNLENMYGSPESLSRVFERAVQYNEPLKVFLHLADIYAKSEKFQEASELYNRMLKRF
RQEKA
PF05843 // ENSGT00390000012228_0_Domain_7 (1866, 2004)
VWIKYGAFLLRRSQAGASRQVLQRALESLPTKEHMDVLAKFAQLEFQLGDAERAR
AIFENMLSTYPKRTDVWSVYIDLTIKHGSQKEV-RDIFERVIHLSLAPKKMKFFFKRYLD
YEKQHGAEKDVLAVKAKALEYVEEARSSVREED
ENSGALP00000013431 (view gene)
-MASMEENFPRGGIQKKPTGTTGKKAKPKFEQDNLFDVH---HEEQTQKRK-RSEGDHRK
Q----KKFKADIKAPAKDIAISIEPLTIKELCEGMLFLGCIKEVTVFELVISLPNGLTGF
VPVTHISDAYSELLSKQVTQGELLEDLNSLSDLYSPGMLVRCVVTSVEKSADGRRSIKLS
INPKSVNKGLSASALTSGMLLSGFVSSVEDHGYLIDIGVSGTHAFLPHQKAQNYIKAVKR
GSDLKIGQSLNCVIEEVKNEGRVVRLSADRSEVAASIATEQQNWTLSNLLPGLVVKAQVQ
KVAPLGVSLTFLSSFTGIVDFMHVDPEKSTNYSPNQMVKACILSTHPTSKVVRLTLRQAF
LHPGGSPNQLSNDRIGAVVEESTVKAFYKQFGAVFQLDDGMLAFARP------KHLSKTR
KSFKPAAFKAGCKHKCRIIDYSLMDEMCIVSLKHQIIEARFLRYEDIHTGDVMQGKVLSL
KPIGMQVKVTDGIKGLVPSMHLADVILKQPEKKYNVGDEVRCRVLECNPAEKKLFLTLKK
TLVQSKLPVLSSYEDAEPGLITHGF
PF00575 // ENSGT00390000012228_0_Domain_3 (566, 628)
VVCAREFGCIVKFYNDVKGLVPKNELSS-EPISCP
DKVFHDGQVVKVMVLKCEPQQERLLLS
ENSGT00390000012228_0_Linker_3_4 (628, 759)
FRLSSRTVPEGRSEC-IPKKKQQVKYQIGEMVD
VEVLKKNENGLEVSILEDGGNVIAWLPTVHLSDFVANSKLLWHCLQEGDVLPRVM---CL
SDKGDRIILCRKSAVISAVQEEQVVRSFSEIQPGVLLI
PF00575 // ENSGT00390000012228_0_Domain_4 (759, 823)
GYVRKVMPFGVFVEFPFGVTGL
APKVSMSDKFVTDTKDHFVVGQTVIAKVMSIDEEKQRVLLSL
ENSGT00390000012228_0_Linker_4_5 (823, 1078)
KVSECSSGDSAAESFSLL
NQYFKEVEEIRNLLR--RREESGLARCVCELVPGKELQLVVQDVMEDGSALFSGGCVRGL
-TVTATRYHLGGKNVIPGEKAKGLVLHVDAITSKVYVSLREELLKKRAKQRLTKNSQHPA
IVQHIAEEFAIVSLLD--SGRLAAIPIASHFNDTFRFDSEKLKVGQRIYATLKMVKANDL
GVLLAVQDPAKKNAFVRDRKESETALE------------------ETLAAAVKHSLS
PF00575 // ENSGT00390000012228_0_Domain_5 (1078, 1139)
LGD
IVTGTVKSVKPTHVTVAIDDKLTGSIHASRILDEVPIHSFPTYTLKAGQKVTARVIGGRD
VNTHRYLPITHPHFTRSVPELSIRPSEIE-----GEVETM--RDDT--REKLGPYNTGQT
VTCFVRKYNTLKNWLEVEVTPDVRGRVPRLLLSLNTKVLKHPEK-NFKNGQA-LSATVTG
TDATET-NLFLSL-TGIQSLEPGTITVGMVAKMIPHIGLTITLPGGKAGKVSIFHLSDKY
TESPLSDFKIGKVVRCYILSNENGKIQLS---LRQSRLNPRNSRKVEDVEITCIKDVKKG
QLVRGYVKSVT-PSGVFFGLSASLLGRILFQNVSPYFVQKHSLYEKYLPEGKLLTAKVLD
----------------VNKKENHVELSLLPEDTEMPSVLPESLGLPRCGAEEEKREEDNK
EKKEE-----VKMKRKQ--RRVNSESEQ--------------------------------
-----------E----TK-----PKKRKFSPADEN----DSGIEVYYREEEDGDQEEEAA
K-----------------------------K-KSKIRKCGEVPRLQVSAGFTWDEDMNAL
EVPVLNQKEESSESEEEEENLQSKK---KQTKKEKELEKQKKEKELCKLEAALMDPSRQP
QSADDFDRLVLSSPNSSILWLQYMAFHLQATEIEKARAVAERALKTICFRE-EQEKLNVW
VALLNLENMYGTEETLMKVFERAVQYNEPLKVFQHLCDIYASSEKYKQAEELYHTMLRRF
RQEKSVWLKYASFLLKQGQTEATHRLLERALKALPTKEHVDVISR
PF05843 // ENSGT00390000012228_0_Domain_7 (1906, 2009)
FAQLEFRFGDPEHAK
ALFESTLNSYPKRTDIWSIYMDIMIKQGSQKEI-RDIFERVIHLNLAPKKMKFFFKRYLD
YEKKYGTTETVMAVKTAALEYVEAKSSLADT--
ENSPANP00000020946 (view gene)
-MAALEESFPRGGTRK--IHKPEKAFQQSVEQDNLFDIS---TEEGSTKRK-KSQKGPAK
T----KKLKIEKRESSKSAREKFEILSVESLCEGMRILGCVKEVNELELVISLPNGLQGF
VQVTEICDAYTKKLNEQVTQEQPLKDLLHLPELFSPGMLVRCVVSSLGITDRGKKSVKLS
LNPKNVNRVLSAEALKPGMLLTGTVSSLEDHGYLVDIGVDGTRAFLPLLKAQEYIRQKNK
GAKLKVGQYLNCIVEKVKGNGGVVSLSVGHSEVSTAIATEEQSWTLNNLLPGLVVKAQVQ
KVTPFGLTLNFLTFFTGMVDFMHLDPKKAGTYFSNQAVRACILCVHPRTRVVRLSLRPIF
LQPGRPLTRLSCQNLGTVLDDVPVQGFFKKAGATFRLKDGVLAYARL------NHLSDSK
NVFNPEAFKPGNTHKCRIIDYSQMDELALLSLRTSIIEAQYLRYHDIEPGAVVKGIVLTI
KSYGMLVKVGEQMRGLVPPMHLADILMKNPEKKYHIGDEVKCRVLLCDPEAKKLMMTLKK
TLVESKLPVITCYADAKPGLQTH
PF00575 // ENSGT00390000012228_0_Domain_3 (564, 628)
GFIIRVKDYGCIVKFYNNVQGLVPKHELST-EYIPDP
ERVFYTGQVVKVAVLNCEPSKERMLLS
ENSGT00390000012228_0_Linker_3_4 (628, 759)
FKLSSDPEPKKE--PAGHSQKKGKAINIGQLVD
VKVLEKTKDGLEVAVLPH--NIRAFLPTSHLSDHVANGPLLHHWLQAGDILHRVL---CL
SQSEGHVLLCRKPALVSTVEGGQDPKNFSEIHPGMLLI
PF00575 // ENSGT00390000012228_0_Domain_4 (759, 823)
GFVKSIKDYGVFIQFPSGLSGL
APKAIMSDKFVTSTSDHFVEGQTVAAKVTNVDEEKQRMLLSL
ENSGT00390000012228_0_Linker_4_5 (823, 1077)
RLSDCALGDLATTSLLLL
SQCLEELQGVRSLMS--NR-DSVLIQTLAEMTPGMFLDLVVQEVLEDGSVVFSGGPVPDL
-VLRASRYHRAGQEVESGQKKKVVILNVDLLKLEVHVSLHQDLVNRK-AKKLRKGSEHQA
IVQHLEKSFAIASLVE--TGHLAAFSLTSHLNDTFRFDSEKLQVGQGVSLTLKTTEPGVT
GLLLAVEGPAAKRTMRPTRKDSETVDEDE-----------EVDPALTVGTVKKHTL
PF00575 // ENSGT00390000012228_0_Domain_5 (1077, 1139)
SIGD
MVTGTVKSIKPTHVVVTLEDGIIGCIHASHILDDVPEGISPTTKLKVGKTVTARVIGGRD
MKTFKFLPISHPRFVRTIPELSVRPSELE------DGHTALNTHSVSPVEKIKQYQAGQT
VTCFLKKYNVVKKWLEVEIAPDIRGRIPLLLTSLSFKVLKHPDK-KFRVGQA-LRATVVG
PD-SSKAFLCLSL-IGPHKLEEGEVAMGRVVKVTPNEGLTVSFPFGKIGTVSIFHVSDSY
SETPLEDFVPQKVVRCYILSTADSVLTLS---LRSSRTNPETKSKVEDPEINSIQDIKEG
QLLRGYVGSIQ-PHGVFFRLGPSVVGLARYSHVSQHSPSKKALYNKHLPEGKLLTARVLR
----------------LNHQKNLVELSFLPGDTGKPDLLSASLEGPLPKQEERKTEAEER
DQKGEKKNQKRN-----E-K-KNQKGQEE--VELPSK---------EKQQPQKPQAQ--K
RGGRERRESG------SEQERVSKKPKKASPSEED----DSLMDVYYREGKEE-AEETNV
------------------------------LRKEKQTKPAEVPRLQLSSGFAWNVGLDSL
AP-ALPPLAESSDSEEDE-KPHQATK--KKSKKERELEKQKAEKELSRIEEALMDPGRQP
ESADDFDRLVLSSPNSSILWLQYMAFHLQATEIEKARAVAERALKTISFRE-EQEKLNVW
VALLNLENMYGSQESLTKVFERAVQYNEPLKVFLHLADIYAKSEKFQEAGELYNRMLKRF
RQEKA
PF05843 // ENSGT00390000012228_0_Domain_7 (1866, 2008)
VWIKYGAFLLRRSQAEASHRVLQRALECLPSKEHVDVIAKFAQLEFQLGDAERAK
AIFENTLSTYPKRTDVWSVYIDMTIKHGSQKAV-RDIFERVIHLSLAPKRMKFFFKRYLD
YEKQHGTEKDVQAVKAKALEYVEAKSSVLED--
ENSCHOP00000004269 (view gene)
-MATLEESFPRGGIRK--THKSEKAFQQSIEQDNLFDXX---XXXXXXXX-XKSQKRPAT
M----KKLKIENRESNKSLTDKE--ILSESLCEGMRILGCVKEVKDLELVISLPNGLQGF
VXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXLLTGTVSSLEDHGYIMDIGVGGARAFLPLQKAQEYIQQKNK
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XVTPLGLTLNFLSFFTGQVDFMHLDPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXX--XXXXXXXXXLDDVVGFFRKAGA-FKLKDGA-LYARV------SHLSNSK
NFFNPENFKPGNTHKCRIIDYSQMDQMACLSLRTSIIEAQYLRYH
PF00575 // ENSGT00390000012228_0_Domain_1 (466, 539)
DIKPGEVVKGTVHTV
KPYGMLVKVSEQITGLVPSMHLADILMKNPEKKYHVGDEVKCRVLLCDPEAKKLMMTLKK
TLVESKLPAVTCYADAKPCLQTHGFIIRVKDCGCIVKFYNDVQGLVPKHELSG-EYIPDP
ERVFYPGQVMKVVVLSCEPSRERMLLSFKLLSDPEPKKE--RVGQNQKKGKAVNVGQLVD
VKVLEKTKDGLEVAVLPH--RTPAFLPTTHLSDHIANGPLLYHWLQAGDILHRVL---CL
SQSEGHVLLCRKPALVSTIEGGQDPKNFS
PF00575 // ENSGT00390000012228_0_Domain_4 (750, 823)
EIHPGMLLIGFVKSIKEYGVFVQFPSGLSGL
APKAIMSDKFVTSTSDHFVEGQTVVAKVTNVDEEKQRMLLSL
ENSGT00390000012228_0_Linker_4_5 (823, 1075)
RLSDCALGDLATTSLLLL
SQCLEELQGVRSLMS--NR-DSLLIQTLSEMIPGMVLDLEVQEVLEDGSVIFSGGPVPDL
-VLRASRYHQAGQEVESGQKKKAVILSVDMLKLEVHVSLCQDLVTRK-AKKLKKGSEHQA
IVQHLEESFAIASLVE--TGHLAAFSLTSHLNDTFRFESEKLHVGQGVSLTLKTTEPGVT
GLLLAVEGPAAKRTMGKTRKESETVDEDE-----------EVDPALVVGTIKKH
PF00575 // ENSGT00390000012228_0_Domain_5 (1075, 1150)
TLSIGD
MVTGTVKSIKATHVVVTLEDGVIGCIHASHILDDVPVGTSPTVKLKVGKTVTARVIGGRD
VKTFKFLPISHPKFIRTIPELSIRPSELE------DGHTALNTHSVSPLEKIKQYQAGQT
VTCFLKRYNVVKKWLEVEIAPDIRGRIPLLLASLSFKVLKHPDK-KFQIGQA-LRATVVG
PD-SSKAFLCLSL-IGPHKLVKGEVAMGRVVKVTPNKGLTVSFPFGKIGRVSIFHVSDSY
SETPLEDFVPQQVVRCCVLSTADHVLTLS---LRSSRTNPMTKSKIEDPEINSIKDLKEG
QLLRGYVKAVQ-LHGVLLGLGPSVVGLARYPHISQYSRSKKALCNRYLPEGKLLTAKILS
----------------LNYEKNLVELSFLPGDTGKLDVFSASPELPLVEQEENNIEAEKS
NQTGDKRTQNG-------KEKKSQNGQLE-SLPC------------NKKEPKKPPVK--R
QGSWGCLQSA------SEQXXXXXXXXXXXXXXXX------------XXXX-------XX
------------------------------XX-XXXXXXXX--------XXXXXXXXX--
--------X--XXXXXXX-XXXXXXX---XX--------------------------XXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXQATEIEKARAVAERALKTISFRE-EQEKLNVW
VALLNLENMYGSQESLTKVFERAVQYNEPLKVFLHLADIYTKSEKFQEAGELYNRMLKRF
RQEKAVWIKYGAFLLRRGQAGASHRVLQRALECLPNKE----------------------
------------------------------------------------------------
---------------------------------
ENSBTAP00000012818 (view gene)
-MAAMEESFPRGGTRKTHKSE--KAFQQSVEQDNLFDIS---TEEESTKRK-KIQKGPAK
T----KKLKVETRQSSKFVREKFEILNVESLCEGMRILGCVKEVNELELAISLPNGLQGY
VQVTEICDAYTEKLNEQVAQEEPLQDLVGLPELFSPGMLVRCVVSSLDTTKGSKKNVMLS
LNPKNVNRVLSAETL
PF00575 // ENSGT00390000012228_0_Domain_0 (196, 268)
KPGMLLTGTVSSLEDHGYLVDIGVSGARAFLPLQKAQEYIRQKNK
GAKLKVGQYLNCLIEEVKGSRGVVTLSIGHSEVSAAIATEEQSWTLNSLLPGLVVKAQVQ
KVTPLGLTLKFLSFFSGLVDFMHLDPKKAGTYFSNQQVRACVLCVHPRTRAVRLSLRPVF
LQPGRPLTRLLCQQLGAVLDDVPVQGFFGSAGATFKLKDGTLAYARR------NHLSNSK
KTFKPEAFKPGNTHKCRIIDYSQMDELALLSLRTSIIEAQFLWYHDIKPGALVKGKVLTI
KPHGMVVKMGKQIRGLVPTMHLADILIKNPEKKYHVGDEVKCRVLLCDPKAKKLMMTLKK
TLVESKLPAITCYDDAKPGLQTH
PF00575 // ENSGT00390000012228_0_Domain_3 (564, 628)
GFILRVKDYGCIVKFYNDVQGLVPRHELSA-EYVPDP
ESVFYTGQVVKVVVLNCEPSKERMLLS
ENSGT00390000012228_0_Linker_3_4 (628, 753)
FRLLSDPK--QE--GEGQSQKKKKAVSAGQLVD
VKVLEKTKDGLKVAVLPH--NIPGFLPTAHLSDHVTNGPLLYHWLQTGDTLHRVL---CL
SVSEERVLLCRKPALVSAVEGGQNPKSFSEIH
PF00575 // ENSGT00390000012228_0_Domain_4 (753, 823)
PGMLLIGFVKNIKDYGVFVQFPSGLSGL
APKAILSDKFVTSTSDHFVEGQTVVAKVTNVDEEKQRMLLSL
ENSGT00390000012228_0_Linker_4_5 (823, 1078)
RLSDCTLGDLATTSLLLL
SQCLEERQGVRSLMS--NR-DSVLIQTLAEMTPGMALDLEVQEVLEDGSVLFSEGPVPGL
-VLRASKYHRAGQELEPGQKKKAVILNVDMLKLEVHVSLCHDLVNRK-AKKLKKGSDLQA
IVQHLEESFAVASLVE--TGHLAAFSLTSHLNDTFRFDSEKLQVGQGVSLTLQTTEPGVT
GLLLAIEGPAAKRTMRQTRKDSETVDEDE-----------EVDPALVVGTVKKHTLS
PF00575 // ENSGT00390000012228_0_Domain_5 (1078, 1138)
IGD
VVTGTVKSIKPTHVVVTLEDGIIGCIHASHILDDVPVGTSPTAKLKVGKKVTARVIGGRD
MKTFKFLPISHPRFIRTIPELSVRPSELK-----EDGHTTLNTHSVSPLEKIKQYQPGQT
VTCFLKKSIMVKKWLEVEIAPDFRGRIPLLLTSLSFKVLKHPDK-KFQIGQA-LKATVVG
PAESSKAFLCLSL-IGPHKLKKGEVAMGRVVKVTPKEGLTVSFPFGRVGRVSMFHVSDSY
SETHLEDFVPQQVVRCYVLSAATPVLTLS---LRSSRTNPETKSKITDPEINSIEDLEEG
QLLRGFVKSVQ-PSGVLVGLGPSVTGLARHPHVSQHNQSKNAPYDRHLPEGKLLTAKVLR
----------------LNHQESLVELSLLPDATGKQDVLSAPLGQPPPKQEGRETEAVER
NHEGKA----KEKKKQKQKEKRTGKGQE--GAQPPSK---------DKKEPQKPQAK--K
LGKRPHPESS------SEQEIGNKKQKKAALSEED----DSGVEVYYREGEE--AEEMSM
------------------------------LPKEKLTRPAEAPRLQLSSGFVWDVGLDTL
TP-ALPPHGDSSDSEEDE-KPEQATQKK-KSKKERELEKQKAEKELSRIEEALMDPGRQP
ESAEDFDRLVLSSPSSSLLWLQYMAFHLQATEIEKARAVAERALKTISFRE-EQEKLNVW
VALLNLENMYGSQESLTKVFERAVQYNEPLKVFLHLADIYTKSEKFQEAGELYNRMLKRF
RQEKA
PF05843 // ENSGT00390000012228_0_Domain_7 (1866, 2007)
VWVKYGAFLLRRGKAEASHRVMQRALECLPKKEHVDVIAKFAQLEFQLGDAERAR
AIFESTLSIYPKRTDVWSVYIDMIIKHGSQKEA-RAIFERVIHLSLAPKRMKFFFKRYLD
YEKQHGSEKDVQAVKAKALEYVEAKSSMMDD--
MGP_PahariEiJ_P0022032 (view gene)
-MANLEESFPRGGTRK--PHKSEKSSQQVVEQDNLFDVS---TEEGPIKRK-KSQKGPAK
T----KKLKIEKRKSIKSMKEKFEILSLESLCEGMRILGCVKEVNELELVVSLPNGLQGF
VQVTEVCDAYTQKLNEQVAQEEPLEDLLRLPELFSPGMLVRCVVSSLDVTESGKKSVKLS
VNPKRVNKVLSAEALRPGMLLTGTVSSLEDHGYLVDIGVGGTRAFLSLQKAQEYIRQKNK
GAKFKVGQYLTCLVEEVKSNGGVVGLSVEHSEVSSAFATEEQGWNLNNLLPGLLVKAQVQ
KVTQFGLQLNFLTFFTGLVDFMHLEPKKMGSYSSNQTVKACILCVHPRTRVVRLSLRPIF
LHPGRPLTRISYQQLGAVLDNVPVQGFFKNAGAIFRLKDGVLAYARV------SHLSNSK
KAFNAEAFKPGSTHKCRIIDYSQMDELALLSLRKSIITAPFLRYHDIKTGTVVKGTVLAI
KPFGILVKVGEQMKGLVPSMHLADVMMKNPEKKYSPGDEVKCRVLLCEPEAKKLIMTLKK
TLVTSKLPAITCYEDAKPGLQT
PF00575 // ENSGT00390000012228_0_Domain_3 (563, 628)
HGVIIRVRDYGCIVKFYNGVQGLVPKHELST-QHIPDP
EKVFYTGQVVKVAVLSCEPSKERMLLS
ENSGT00390000012228_0_Linker_3_4 (628, 754)
FRLLSDSEPKEE--SVENSQKKARAVNIGQLVD
VKVLEKTKTGLEVAILPH--NIPAFLPTPHLSDHVANGPLLHHWLQTGDTLHRVL---CL
SQSERHVLLCRKPALVSTVEGGQDPKSLSEIQP
PF00575 // ENSGT00390000012228_0_Domain_4 (754, 823)
GMLLIGFVKCIKEYGVFVQFPSGLSGL
SPKAIMSDKFVTTPSEHFVEGQTVVAKVTNVDESKQRMLLSL
ENSGT00390000012228_0_Linker_4_5 (823, 1077)
RLSDCSLGDSASTSFLLL
CQCLEELQGIRSLMS--NQ-DSVLIQTLADMTPGMVLDAMVQEVLEDGSVVFSVDPVPDL
-VLRASKYHRAGQEVEPGQKKKVVVLHVDMLKLEVHVSLHQDLMNRK-SQKLRKSSRHQG
IVQHLEESFAVASLVE--TGHLVAFSLISHLNDTFHFDSEKLRVGQGVCLTLKTTEPGVT
GLILAVEGPASKRTRMPARRDSETVDDKGEEEEKE--EEEEEEEDLTVKSKKRHSL
PF00575 // ENSGT00390000012228_0_Domain_5 (1077, 1142)
AIGD
KVTGTIKSVKATHVVVALADGFVGCIHASRILDDVPVGTSPTATLKVGKKVTARVIGGRD
VKTSKFLPISHPRFVLTILELSVRPSELK-----G-SYHALNTHSVSPVEKIQQYQAGQT
VTCFFKKYNVMKKWLEVDIGPDIRGRIPLLLTSLSFKVLKHPDK-KFQIGQA-IKATVVD
PD-VPRAFLCLSL-IGPYRLEEGEVAMGRVMKVVPNRGLTVSFPFGKIGKVSIFHLSDSY
SETPLEDFCPQKIVRCYVLSTAHHVLALS---LRSSRTNRETKNRIEDPEVNSIEDVKEG
QLLRGYVKRVL-PSSVIIGLGPSVLGLAKYSHVSECIPPERELYNRCLPEGKLVTAKILC
----------------VNPMKNLIELSLLPSDTGRPDVFSPDPE-----QEERRGGAEG-
GLKGE--KKKSQR---R--GEEPQ---------LPSQ---------EKEEPRKSQRG--G
QGKRERQESE------SRQELVNKRPKKSGSPEDD----DSGVEVYYREGKDE-LEEPKL
------------------------------PPRGKQIKPTEVPRLQLSSGFVWDVGLDSL
TP-ALPLREESSDSEEDEQPPHAKKK--KKGKKERELEKQKAEKELSRIEEALMDPGRQP
ESADDFDRLVLSSPNSSILWLQYMAFHLQATEIEKARAVAERALKTISFRE-EQEKLNVW
VALLNLENMYGSQESLTKVFERAVQYNEPLKVFLHLADIYTKSDKFKEAGELYNRMLKRF
RQEKAVWIKYGAFVLGRSQAGASHRVLQRALECLPAK
PF05843 // ENSGT00390000012228_0_Domain_7 (1898, 2006)
EHVDVIVKFAQLEFQLGDAERAK
AIFENTLSTYPKRTDVWSVYIDMTIKHGSQKAV-RDIFERVIHLSLAPKRMKFFFKRYLD
YEKQHGTEKDVQAVKAKALEYVEAKSSALED--
ENSCSAP00000001658 (view gene)
-MAALEESFPRGGTRK--IHKPEKAFQQSVEQDNLFDIS---TEEGSTKRK-KSQKGPAN
T----KKLKIEKRESSKSAREKFEILSVESLCEGMRILGCVKEVNELELVISLPNGLQGF
VQVTEICDAYTKKLNEQVTQEQPLKDLLHLPELFSPGMLVRCVVSSLGITDRGKKSVKLS
LNPKNVNRVLSAEAL
PF00575 // ENSGT00390000012228_0_Domain_0 (196, 268)
KPGMLLTGTVSSLEDHGYLVDIGVDGTRAFLPLLKAQEYIRQKNK
GAKLKVGQYLNCIVEKVKGNGGVVSLS
ENSGT00390000012228_0_Linker_0_1 (268, 468)
VGHSEVSTAIATEEQSWTLNNLLPGLVVKAQVQ
KVTPFGLTLNFLTFFTGVVDFMHLDPKKAGTYFSNQAVRACILCVHPRTRVVRLSLRPIF
LQPGRPLTRLSCQNLGAVLDDVPVQGFFKKAGATFRLKDGVLAYARL------SHLSDSK
NVFNPETFKPGNTHKCRIIDYSQMDELALLSLRTSIIEAQYLRYHDI
PF00575 // ENSGT00390000012228_0_Domain_1 (468, 539)
EPGAVVKGVVLTI
KSYGMLVKVGEQMRGLVPPMHLADILMKNPEKKYHIGDEVKCRVLLCDPEAKKLMMTLKK
TLVESKLPVITCYADAKPGLQTHGFIIRVKDYGCIVKFYNNVQGLVPKHELST-EYIPDP
ERVFYTGQVVKVAVLNCEPSKERMLLSFKLSSDPEPKKE--PAGHNQKKGKAINIGQLVD
VKVLEKTKDGLEVAVLPH--NIRAFLPTSHLSDHVANGPLLHHWLQAGDILHRVL---CL
SQSEGHVLLCRKPALVSTVEGGQDPKNFSEIH
PF00575 // ENSGT00390000012228_0_Domain_4 (753, 823)
PGMLLIGFVKSIKDYGVFIQFPSGLSGL
APKAIMSDKFVTSTSDHFVEGQTVAAKVTNVDEEKQRMLLSL
ENSGT00390000012228_0_Linker_4_5 (823, 1078)
RLSDCALGDLATTSLLLL
SQCLEELQGVRSLMS--NR-DSVLIQTLAEMTPGMFLDLVVQEVLEDGSVVFSGGPVPDL
-VLRASRYHRAGQEVESGQKKKVVILNVDLLKLEVHVSLHQDLVNRK-AKKLRKGSEHQA
IVQHLEKSFAIASLVE--TGHLAAFSLTSHLNDTFRFDSEKLQVGQGVSLTLKTTEPGVT
GLLLAVEGPAAKRTMRPTRKDSETIDEDE-----------EVDPALTVGTIKKHTLS
PF00575 // ENSGT00390000012228_0_Domain_5 (1078, 1138)
IGD
MVTGTVKSIKPTHVVVTLEDGIIGCIHASHILDDVPEGISPTTKLKVGKTVTARVIGGRD
MKTFKFLPISHPRFVRTIPELSVRPSELE------DGHTALNTHSVSPVEKIKQYQAGQT
VTCFLKKYNVVKKWLEVEIAPDIRGRIPLLLTSLSFKVLKHPDK-KFRVGQA-LRATVVG
PD-SSKAFLCLSL-IGPHKLEEGEVAMGRVVKVTPNEGLTVSFPFGKIGTVSIFHVSDSY
SEMPLEDFVPQKVVRCYILSTADSVLTLS---LRSSRTNPETKSKVEDPEINSIQDIKEG
QLLRGYVGSIQ-PHGVFFRLGPSVVGLARYSHVSQHSLSKKALYNKHLPEGKLLTARVLR
----------------LNHQKNLVELSFLPGDTGKPDLLSASLEGPLPKQEERKTEAEER
YQKGEKKNQKRN-----E-K-KNQKGQEE--VELPSK---------EKQQPQKPQAQ--K
RGGRERRESG------SEQERVSKKPKKAGPSEED----DSLMDVYYREGKEE-AEETNV
------------------------------LPKEKQTKPAEVPRLQLSSGFAWNVGLDSL
TP-ALPPLAESSDSEEDE-KPHQTTK--KKSKKERELEKQKAEKELSRIEEALMDPGRQP
ESADDFDRLVLSSPNSSILWLQYMAFHLQATEIEKARAVAERALKTISFRE-EQEKLNVW
VALLNLENMYGSQESLTKVFERAVQYNEPLKVFLHLADIYAKSEKFQEAGELYNRMLKRF
RQEKA
PF05843 // ENSGT00390000012228_0_Domain_7 (1866, 2008)
VWIKYGAFLLRRSQAGASHRVLQRALECLPSKEHVDVIAKFAQLEFQLGDAERAK
AIFENMLSTYPKRTDVWSVYIDMTIKHGSQKAV-RDIFERVIHLSLAPKRMKFFFKRYLD
YEKQHGTEKDVQAVKAKALEYVEAKSSVLED--
ENSMUSP00000072008 (view gene)
-MANLEESFPRGGTRK--LHKSEKSSQQVVEQDNLFDVS---TEEGPIKRK-KSQKGPAK
T----KKLKIEKRKSIKSIKEKFEILSLESLCEGMRILGCVKEVSELELVVSLPNGLQGF
VQVTEVCDAYTQKLNEQVAQEEPLEDLLRLPELFSPGMLVRCVVSSLDVTESGKKSVKLS
VNPKRVNKVLSADALR
PF00575 // ENSGT00390000012228_0_Domain_0 (197, 268)
PGMLLTGTVSSLEDHGYLVDIGVGGTRAFLSLKKAQEYIRQKNK
GAKFKVGQYLTCVVEEVKSNGGVVSLS
ENSGT00390000012228_0_Linker_0_1 (268, 468)
VEHSEVSSAFATEEQSWNLNNLLPGLLVKAQVQ
KVTQFGLQLNFLTFFKGLVDFMHLEPKKMGSYSSNQTVKACILCVHPRTRVVRLSLRPIF
LHPGRPLTRISYQQLGAVLDDVPVQGFFKNAGAIFRLKDGVLAYARV------SHLSDSK
KAFNAEAFKPGSTHKCRIIDYSQMDELALLSLRKSIIAAPFLRYHDI
PF00575 // ENSGT00390000012228_0_Domain_1 (468, 539)
KIGTVVKGTVLAI
KPFGILVKVGEQIKGLVPSMHLADIMMKNPEKKYSPGDEVKCRVLLCDPEAKKLIMTLKK
TLVTSKLSLITCYEGAKPGLQTHGVIIRVKDYGCIVKFYNDVQGLVPKHELST-QHIPDP
ETVFYTGQVVKVAVLSCEPSKERMLLSFRLLSDSRPKDP--GVESSQKKTGAVRIGQLVD
VKVLEKTKTGLEVAILPH--NTPAFLPTPHLSDHAANGPLLHHWLQTGDTLHRVL---CL
SQSERHILLCRKPALVSTVEGGQDPKSLSEIQP
PF00575 // ENSGT00390000012228_0_Domain_4 (754, 823)
GMLLIGFVKCIKEYGVFVQFPSGLSGL
SPKTIMSDKFVTTPSEHFVEGQTVVAKVTNVDESKQRMLLSLRLSDCSLGDSASTSFLLL
CQCLEELQGIRSLMS--NQ-DSVLIQTLADMTPGMVLDAVVHEVLEDGSVVFSSDPVPDL
-VLRASRYHRAGQEVEPGQKKKVVVLHVDMLKLEVHVSLHQDLVNRK-TRKLRKSSRHQG
IVQHLEESFAVASLVE--TGHLVAFSLISHLNDTFHFDSEKLRVGQGVCLTLKTTEPGVT
GLILAVEGPASKRTRMPVQRDSETVDDKGEEKEEEEEEEEKEEENLTVKSKKRHSLAIGD
KVTGTIKAVKATHVVVTLADGFVGCIHASRILDDVPVGTSPTTTLKAGKKVTARVIGGRD
VKTSKFLPISHPRFVLTILELSVRPSELK-----G-SYSALNTHSESPVEKIRQYQAGQT
VTCFFKKYNVMKKWLEVDIGPDIRGRIPLLLTSLSFKVLKHPDK-KFQVGQA-IEATVVD
PD-VPRAFLCLSL-IGPYRLEEGEVAMGRVMKVVPNRGLTVSFPFGKIGKVSMFHLSDSY
SEAPLEDFCPQKIVRCYILSTAHRVLALS---LRSSRTNRETKNRIEDPEINSIEDVKEG
QLLRGYVKCVL-PSSVIIGLGPSVLGLAKYSHVSECVPPEKELYNGCLPEGKLVTAKVLR
----------------VNPMKNLIELSLLPSDTGRPDVFSPAPEP---KQEERSGGAEE-
GQKRK--EKN-------------Q---------KRRE---------EKEEPQKSQRG--G
RGKRERQESE------SEQELVNKRPKKSGAAEED----DSGVEVYYREGEDE-VGEPKL
------------------------------PPRGKQTKSTEVPRLHLSSGFLWDVGLDSL
TP-ALPLREESSDSED--EQPHQAKK--KKGKKERELEKQKAEKELSRIEEALMDPGRQP
ESADDFDRLVLSSPNSSILWLQYMAFHLQATEIEKARAVAERALKTISFRE-EQEKLNVW
VALLNLENMYGSQESLTKVFERAVQYNEPLKVFLHLADIYTKSEKYKEAGELYNRMLKRF
RQEKAVWIKYGAFVLGRSQAGASHRVLQRALECLPAK
PF05843 // ENSGT00390000012228_0_Domain_7 (1898, 2006)
EHVDVIVKFAQLEFQLGDVERAK
AIFENTLSTYPKRTDVWSVYIDMTIKHGSQTAV-RDIFERVIHLSLAPKRMKFFFKRYLD
YEKQHGTEKDVQAVKAKALEYVEAKSSALED--
ENSLAFP00000007049 (view gene)
-MATLEESFPRGGTRKAHKSE--KAFQQSVEQDNLFDIT---TEEESTKRK-KSQKGPAK
T----KKLKIEKRENIKLVKEKFEILTVETLCEGMRILGCVKEVSDLELVISLPNGLKGF
VQVTEICDAYTKKLNEQVAQEEPLKDLVRLPELFSPGMLVRCVVSSVGITEKGKKSVKLS
LNPRNVNGVLSAE
PF00575 // ENSGT00390000012228_0_Domain_0 (194, 269)
ALKPGMLLTGTVSSLEDHGYLVDIGVSGNRAFLPLQKAQEDTRQKNK
GAKLKVGQYLNCVIEEVKSSGGVVSLSV
ENSGT00390000012228_0_Linker_0_1 (269, 466)
GHSEVSTAIATEEQNWTLNNLLPGLVVKGQVQ
KVTPFGLTVNFLSYFTGLVDFMHLEPKKTGTYFSNQAVRACILFIHPRTRAVRLSLRPVF
LQPGRPLTRLSCQHLGAVLDDLPVHGFFNKAGATFKLKDGALAYARF------SHLSNSK
NVFKPEIFKPGNTHKCRIIDYSPMDELALLSLRTSIIEAQYLSYH
PF00575 // ENSGT00390000012228_0_Domain_1 (466, 539)
DTKPGAVVKGTVLTI
KPYGMLVKVGEQIRGLVPPMHLADILMKNPEKKYSVGDEVKCRVLVCDPEAKKLMMTLKK
TLVESRLPAITCYADAKPGLQTHGFILRVKDCGCIVKFYNDVQGLVPKHELSA-EYIPAP
ETVFYPGQVMKVVVLNCEPAKERMLLSFKLLSDPEAKKE--REGGSQKKRRAVHVGQLVD
VKVVEKTEDGLEVAVLPH--SIPGFLPIPHLSDHVPNGPLLYHWLQAGDTLHRVL---CL
Q-SEGRVLLCRKPALVSAVEGGQDPKSFS
PF00575 // ENSGT00390000012228_0_Domain_4 (750, 823)
EIHPGMLLMGFVKSIKDYGVFVQFPSGLSGL
APKAAMSDKFVTSTSDHFVEGQTVVAKVTNVDEEKQRMLLSL
ENSGT00390000012228_0_Linker_4_5 (823, 1075)
RLSDCTLGDVATTSLLLL
SQCLEELQGVRSLMS--NR-DSVLIQTLAEMTPGMILDLEVQEVLEDGSVVFGGGPVPGL
-VLRASRYHRAGQEVESGQKKKAVVLNVDMLKLEVHVSLCQDLVNRK-HKKLKKGSEYQA
TVQHLEESFAIASLVE--TGQLAAFSLTSHLNDTFRFDSEKLQVGQGVSLALKATQPGVT
GLILAVEGPAAKRTMRQTRKESETVDEDE-----------ESDPALVVGTVKKH
PF00575 // ENSGT00390000012228_0_Domain_5 (1075, 1150)
TLSIGD
MVTGTVKSIKATHVVVTLEDGVIGCIHASNILDDVPVGTSPTSKLKVGKTVTARVIGGRD
VKTYKFLPISHPRFIRTIPELSVRPSELE-----KDGHTALNTHSVSPSEKIKQYQAGQT
VTCFLKRYNVVKKWLEVEIAPDIRGRIPLLLTSLSFKVLKHPDK-KFRIGQA-LNATVVG
PD-SCKAFLCLSL-IGPHKLEKGEVAMGRVVKVTPNEGLTVSFPFGKFGRASIFHVSDSY
SETPLEDFVPQKIVRCCVLSTAGHVLTLS---LRSSRTNPETKSKIEDPEINSIQDIEEG
QLLRGYVKAVE-PHGVLFSLGPSVVGLARYSHVSQYSPSKKALYSRYLPEGKLLTAKILS
----------------LNHKRSLVRLSFLPSDTGKPDVLPASIGLPRLSE----------
----------------------------------------------EKSEPRQPQVK--K
QGKRGRLESG------SEQERVKKKQKKAGPSEED----DSGVEVYYREGEEE-IEEMTV
------------------------------LPKEKPAKLTEVPRLQLSSGFMWDVGLDSL
TP-ALPPRRESSDSEEDE-KPHEATLPLTQGLRSRPLIDFSAFPTLSRIEEALMDPRRQP
ESADDFDRLVLSSPNSSILWLQYMAFHLQATEIEKARAVAERALKTISFRE-EQEKLNVW
VALLNLENMYGSQESLTKVFERAVQYNEPLKVFLHLADIYTKSEKFQEAGELYNRMLKRF
RQEKAVWIKYGSFLLGRGQAGASHRVLQRALECLPQKEHVDVIARFAQLEFQLGDKERAK
AIFENTLSTYPKRTDVWSVYIDMTIKHGTQKEV-RDIFERVIHLSLAPKRMKFFFKRYLD
YEKQHGTEKDVQAVKAKALEYVEAKSSVLED--
ENSCLAP00000001351 (view gene)
-MAAVEESFPRGGTRK--IHKSEKSYQQSVEHDNLFDIS---TEEESTKRK-KNQKGPAK
T----KKLKIEKREKVKSVKEKFEILGIESLCEGMRILGCVKEVNELELVISLPNGLQGF
VQVTEICDAYTRKLNEQVAQEEPVKDLLHLPELFSPGMLVRCVVSSVNVTDKGKKSVKLS
LNPRNVNRVLSAEAL
PF00575 // ENSGT00390000012228_0_Domain_0 (196, 268)
KPGMLLTGTVSSLEDHGYLVDVGVGGTRAFLPLQKAQEYVKQKNK
GANLKVGQYLHCVIEEVKGGGGVVSLS
ENSGT00390000012228_0_Linker_0_1 (268, 468)
IEQSEVSAALATQEQNWTLNSLLPGLVVKAQVQ
KVTPFGLTLNFLTFFTGLVDFMHLDPKKVGTYFSHQAVRACIICVHPRTRAVRLSLRSIF
LQPGRPLTRLSCQHVGAVLQDVPVQGFFNKAGATFRLKDGALAYARL------SHLSDSK
N-LKPEAFKPGNTHKCRIIDYSQMDELALLSLRTSVIEAQYLRYHDI
PF00575 // ENSGT00390000012228_0_Domain_1 (468, 539)
RIGAVIKGTVLTI
KPFGLLVKVGEQMRGLVPAVHLADILMKSPEKKYHIGDEVKCRVLFCDPEAKKLIMTLKK
TLVTSKLPVITCYEDAKPGLQTHGTIVRVKDYGCIVKFYNDVQGLVPKHELSA-QYIPDP
EKVFYTGQVVKVAVLNCEPSKERMLLSFKLLSDQEPKNE--SVGHSQKNEKVISVGQLVD
VKILEKTKGGLQVAVLPH--SVPAFLPTPHLSDHVANGPLLYRWLQAGDTLHRVL---CL
SQNERQVLLCRKPALVSTVEGGQDPKNFSEI
PF00575 // ENSGT00390000012228_0_Domain_4 (752, 823)
QPGMLLLGFVKSIKDYGVFVQFPSGLSGL
APKAIMSDKFVTNPSDHFVEGQTVVAKVTKVDEEKQRMLLSL
ENSGT00390000012228_0_Linker_4_5 (823, 1077)
RLSDCRLGTSSSASLLLL
SQCLEELQGVRSLMS--SR-DSVLIQTLAEMTPGTVLDLAVQEVLEDGSVAFSGSAVPDL
-VLRASRYHRAGQDVESGQKKKAVILSVDMLKLEVHVSLRKELLNRK-ARKLKKGSEHQA
TVQHLEEAFAVASLVE--TGHLVAFSLASHLNDTFRFDSEKLQVGQEVSLVLKTTEPGVT
GLLLAVEGPAAKRVLRQARKDSETVDEGE-----------DDDPALAAGPRKKHTL
PF00575 // ENSGT00390000012228_0_Domain_5 (1077, 1140)
AIGD
LVTGTVKSVKPTHAVVTLEGGVVGCIHASRILDEVPEGTAPTAALKVGKTVTARVIGGRD
VKTFKFLPISHPRFVQTILELSVRPSEVE-----QAGHSALDTYSASLVGKIQQYQAGQT
VTCFLKKYNVVKKWLEVDIAPDIRGRIPLLLTSLSFKVLKRPDK-KFQIGQA-LRATVVG
PD-TSKEFLCLSL-IGPHKLERGEVAMGRVVKVTPREGLTVAFPFGKTGTVSIFHVSDSY
SETPLEEFVPQKVVRCYVLSTADHVLTLS---LRSSRTNPETKSKVEDPEINSTQDIKEG
QLLRGYVRSIK-PNGVLLGLGPSVVGLAQFSHVSQRSLAKKDLYSKYLPEGRLLTAKVL-
---------------RLNHSKNLVELSLLPADTGKPDVLCVSPELLLQE-TDTKGE-EES
---------------P-ERKGKNLHGRA---GELPSK---------EQVKVKKP------
-GKRERPDSGGAQVSPRGGERVSKRQ-KAGP--WE----EDGVDVYYREGEEQ-IAEMRL
------------------------------LPKGTLTKPAEAPRLRLSSGFLWDVGLDSL
TP-ALPPRGESSDSEEDE-KPHQATK--KKSKKERELEKQKAEKELSRIEEALMDPGRQP
ESADDFDRLVLSSPNSSILWLQYMAFHLQATEIEKARAVAERALKTISFRE-EQEKLNVW
VALLNLENMYGSPESLSKAFERAVQYNEPLKVFLHLADIYAKSEKFQEAGELYNRMLKRF
RQEKA
PF05843 // ENSGT00390000012228_0_Domain_7 (1866, 2006)
VWIRYGAFLLRRSQAGASRRVLQRALECLPAKEHMDVIAKFAQLEFQLGDAERAK
AIFENMLSTYPKRTDVWSVYIDLTIKHGSQKEV-RDIFERVIHLSLAPKKMKFFFKRYLD
YEKQHGTEKDVLAVKAKALEYVEAKSAALGD--
ENSCPOP00000009846 (view gene)
-MAALEESFPRGGSRK--IHKSEKSHQPSVEHGNLFDIS---IEEDPPK-G-KDQNGPAK
T----K----------------------KSLCKGMRILGCVKEVNELELVIGLPNGLQGF
VQVTEICDAYTQKLNEQVAQEEPLKDLLRLPELFSLGMLVRCVVSSVSITEQGKKSVKLS
LNPRNVNRVLSAEALKPGMLLTGTVSSLEDHGYLVDIGVEGTRAFLPQQKAQEYIRQKNK
GAKLKVGQYLNCIIEEMKGNGGVVGLSIEQSEISTAIATQEQNWNLNNLLPGLVLQAQVQ
KVTQFGLTLNFFTFFTGLVDFMHLDPKKVGMYFSNQTVRACVLCVHPRTRAVRLSLRPIF
LQPGRPLTRLSCQHLGAVLQDVPVQGFFNKAGATFRLKDGALAYARL------SHLSDSK
NGFRPEAFKPGNTHKCRIIDYSQMDELALLSLRTSVIEAQYLKYHDI
PF00575 // ENSGT00390000012228_0_Domain_1 (468, 539)
KTGAVIKGTVMTI
KPFGMLVKVGEQMRGLVPAMHLADIPMKNPEKKYHVGDEVKCRVLLCDPEAKKLILTLKK
TLVTSKLPVITCYEDAKPGLQTHGAILRVKDYGCIVKFYNDVQGLVPKHELSD-QHIPDP
EKVFYVGQVVKVAVLNCEPSRERMLLSFKLLSDPERKNG--SVERRQKSKKAISVGQLVD
VKILEKTKDGLHVAVLPH--NIPAFLPTPHLSDHVTNGPLLYHWLQAGDTLHRVL---CL
SQSEKQVLLCRKPALVSAVEDGQVPKSFSEIQ
PF00575 // ENSGT00390000012228_0_Domain_4 (753, 822)
PGMLLVGFVKSIKDYGVFVQFPSGLSGL
APKAIMSDKFVTNPSDHFVEGQTVVVKVTKVDEEKQRMLVS
ENSGT00390000012228_0_Linker_4_5 (822, 1078)
LRLSDCRLGSSSSTSLLLL
SQCLEELHGVRSLMGSQGR-DSVLIQTLAKMTPGMVLDLVVQEVLEDGSVVLSGGPVPDL
-VLRASRYHRAGQEVEAGQKRKAVILHVDMLELEVHVSLLKELVNRK-ARKLKKGRKYQA
TVQHLEESFALASLVE--TGHLVAFSLASHLNDTFRFDSEKLQVGQGVCLVLKTTEPGVT
GLLLAVVGPAAQRVLRQTRKDSETVDDDE-----------EGDPALVTGLRRQHTLA
PF00575 // ENSGT00390000012228_0_Domain_5 (1078, 1142)
LGD
TVTGTVKSVKPTHVVVTLEGGLVGCIHASHILDDVVEGSMPTATLKVGQSVTARVIGGRD
VKTSKFLPISHPRFIRTIPELSIRPSELE------QGHTALDTYSASPGEKIEHYQAGQT
VTCFLKKYNVVKKWLEVDIAPDIRGRIPLLLASLSFKVLKHPDK-KFQIGQA-LRATVVG
PD-SSRAFLCLSL-IGPHKLEKGEVAMGRVVKVTPHKGLTVAFPFGRTGTVSVFHMSDSY
SETPLEDFMPQKVVRCYVLSTADHMLTLS---LRLSRTNPETKSKVEDPEIDSMQDVKAG
QLLRGYVQSIE-PSGVLLGLGPSVVGLAQFSHVSQSSPPKKDLYRKYLPEGRLLTAKVL-
---------------RLNHNKNLVELSFLPTDTGRPDVLSVSPELPLQKQEERAKA-KER
DRKEE---S------QQRKEKKNPKGQK--EGKLPNK---------EQTEVKRL------
-GKRERQDSE--------GERVNKRQKKANLLEED----DSGVEVYYREGEEEIEE----
-------------------------------TKGMLPKPAEVPRLRLSSGFLWDVGLDSL
TP-ALPPRGESSDSEEDE-KPHQAMHK-KKSKKERELEKQQSEKELSRIEEALMDPRRQP
GSADDFDRLVLSSPNSSILWLQYMAFHLQATEIEKARAVAERALKTISFRE-EQEKLNVW
VALLNLENMYGSPESLSKVFERAVQYNEPLKVFLHLADIYAKSEKFQEAGELYNRMLKRF
RQEKA
PF05843 // ENSGT00390000012228_0_Domain_7 (1866, 2008)
VWVKYGAFLLRRSQAGACRRVLQRALECLPTKEHMDVITKFAQLEFQLGDAERAK
AIFENMLSTYPKRTDVWSVFIDLTIKHSSQKEI-RDLFERVIHLSLAPKKMKFFFKRYLD
YEKQHGTEKDVLAVKAKALEYVEAKSSVLED--
ENSMLEP00000033729 (view gene)
-MAALEESFPRGGTRK--IHKPEKAFQQSVEQDNLFDIS---TEEGSTKRK-KSQKGPAK
T----KKLKIEKRESSKSAREKFEILSVESLCEGMRILGCVKEVNELELVISLPNGLQGF
VQVTEICDAYTKKLNEQVTQEQPLTDLLHLPELFSPGMLVRCVVSSLGITDRGKKSVKLS
LNPKNVNRVLSAESL
PF00575 // ENSGT00390000012228_0_Domain_0 (196, 268)
KPGMLLTGTVSSLEDHGYLVDIGVDGTRAFLPLLKAQEYIRQKNK
GAKLKVGQYLNCVVEKVKGNGGVVSLS
ENSGT00390000012228_0_Linker_0_1 (268, 468)
VGHSEVSTAIATEEQSWTLNNLLPGLVVKAQVQ
KVTPFGLTLNFLTFFTGVVDFMHLDPKKAGTYFSNQAVRACILCVHPRTRVVRLSLRPIF
LQPGRPLTRLSCQNLGTVLDDVPVQGFFKKAGATFRLKDGVLAYARL------SHLSDSK
NVFNPEAFKPGNTHKCRIIDYSQMDELALLSLRTSIIEAQYLRYHDI
PF00575 // ENSGT00390000012228_0_Domain_1 (468, 538)
EPGAVVKGIVLTI
KSYGMLVKVGEQMRGLVPPMHLADILMKNPEKKYHIGDEVKCRVLLCDPEAKKLMMTLKK
TLVESKLPVITCYADAKPGLQTHGFIIRVKDYGCIVKFYNNVQGLVPKHELST-EYIPDP
ERVFYTGQVVKVAVLNCEPSKERMLLSFKLSSDPEPKKE--PAGHSQKKGKAINIGQLVD
VKVLEKTKDGLEVAVLPH--NIRAFLPTSHLSDHVANGPLLHHWLQAGDILHRVL---CL
SQSEGHVLLCRKPALVSTVEGGQDPKNFSEIHPGMLLI
PF00575 // ENSGT00390000012228_0_Domain_4 (759, 823)
GFVKSIKDYGVFIQFPSGLSGL
APKAIMSDKFVTSTSDHFVEGQTVAAKVTNVDEEKQRMLLSL
ENSGT00390000012228_0_Linker_4_5 (823, 1077)
RLSDCALGDLATTSLLLL
SQCLEELQGVRSLMS--NR-DSVLIQTLAEMTPGMFLDLVVQEVLEDGSVVFSGGPVPDL
-VLRASRYHRAGQEVESGQKKKVVILNVDLLKLEVHVSLHQDLVNRK-AKKLRKGSEHQA
IVQHLEKSFAIASLVE--TGHLAAFSLTSHLNDTFRFDSEKLQVGQGVSLTLKTTEPGVT
GLLLAVEGPAAKRTMRPTRKDSETVDEDE-----------EVDPALTVGTVKKHTL
PF00575 // ENSGT00390000012228_0_Domain_5 (1077, 1139)
SIGD
MVTGTVKSIKPTHVVVTLEDGIIGCIHASHILDDVPEGISPTTKLKVGKTVTARVIGGRD
MKTFKFLPISHPRFVRTIPELSVRPSELE------DGRTALNTHSVSPVEKIKQYQAGQT
VTCFLKKYNVVKKWLEVEIAPDIRGRIPLLLTSLSFKVLKHPDK-KFRVGQA-LRASVVG
PD-SSKAFLCLSL-IGPHKLEEGEVAMGRVVKVTPNEGLTVSFPFGKIGTVSIFHVSDSY
SETPLEDFVPQKVVRCYILSTADSVLTLS---LRSSRTNPETKSKVEDPEINSIQDIKEG
QLLRGYVGSIQ-PHGVFFRLGPSVVGLARYSHVSQHSPSKKALYNKHLPEGKLLTARVLR
----------------LNHQKNLVELSFLPGDTGKPDLLSASLEGPLPKQEERKTEAEER
DQKGEKKNQKRN-----E-K-KNQKGQEE--VELPSK---------EKQQPQKPQAQ--K
RGGLGRGNRE------QPK---------P----------------------GA-FLSTSV
------------------------------FLQEKQTKPAEVPRLQLSSGFAWNVGLDSL
TP-ALPPLAESSDSEEDE-KPHQATK--KKSKKERELEKQKAEKELSRIEEALMDPGRQP
ESADDFDRLVLSSPNSSILWLQYMAFHLQATEIEKARAVAERALKTISFRE-EQEKLNVW
VALLNLENMYGSQESLTKVFERAVQYNEPLKVFLHLADIYAKSEKFQEAGELYNRMLKRF
RQEKA
PF05843 // ENSGT00390000012228_0_Domain_7 (1866, 2008)
VWIKYGAFLLRRSQAGASHRVLQRALECLPSKEHVDVIAKFAQLEFQLGDAERAK
AIFENTLSTYPKRTDVWSVYIDMTIKHGSQKAV-RDIFERVIHLSLAPKRMKFFFKRYLD
YEKQHGTEKDVQAVKAKALEYVEAKSSVLED--
ENSANAP00000033853 (view gene)
-MATLEESFPRGGTRK--IHKPEKAFQQSVEQDNLFDIS---TEEGFTKRK-KSQKVPAK
T----KKLKIEKRESSKSAREKFEILSVESLCEGMRILGCVKEVNELELVISLPNGLQGF
VQVTEISDAYTKKLNEQVTQDQPLKDLLHLPELFSPGMLVRCVVSSLGITERGRKSVKLS
LNPKNVNRVLSAEALKPGMLLTGTVSSLEDHGYLVDIGVDGTRAFLPLLKAQEYIRQKNK
GAKLKVGQYLNCIIEKVKGNGGVVHLSIGHSEVSTAIATEEQSWTLNNLLPGLVVKAQVQ
KVTPFGLTLNFLTFFTGVVDFMHLDPKKAGTYFSNQAVKACILCIHPRTRVVRLSLRPIF
LQPGRPLSRLSCQHLGAVLNDVPVQGFFKKAGATFRLKDGVLAYARL------SHLSDSK
NVFNPEAFKPGNTHKCRIIDYSQMDELALLSLRTSIIEAQYLRYHDIKPGAVVKGTVLTI
KPYGMLVKVGEQMRGLVPPMHLADILMKNPEKKYHIGDEVKCRVLLCDPEAKKLMMTLKK
TLVESKLPAITCYADAKPGLQTH
PF00575 // ENSGT00390000012228_0_Domain_3 (564, 628)
GFIIRVKDYGCIVKFYSDVQGLVPKHELST-EYIPDP
ERVFYTGQVVKVAVLNSEPSKERMLLS
ENSGT00390000012228_0_Linker_3_4 (628, 756)
FKLLRDPEPKKE--PAGHNQKKGKAINVGQLVD
VKVLEKTKDGLEVAVLPH--NTCAFLPTSHLSDHVTNGPLLHHWLQAGDTLHRVL---CL
SQSEGHVLLCRKPALVSTVEGGQDPKSFSEIHPGM
PF00575 // ENSGT00390000012228_0_Domain_4 (756, 823)
LLVGFVKSIKDYGVFIQFPSGLSGL
APKAIMSDKFVTSTSDHFVEGQTVVAKVTNVDEEKQRMLLSL
ENSGT00390000012228_0_Linker_4_5 (823, 1077)
RLSDCGLGDLATTSLLLL
SQCLEELQGVRSLMS--NR-DSVLIQTLAEMTPGMFLDLVVQEVLEDGSVVFSGGPVPNL
-VLRASRYHRGGQEVESGQKKKVVILNVDLLKLEVHVSLHQDLVNRK-ARKLRKGSKHQA
IVQHLEKSFAIASLVE--TGHLVAFSLTSHLNDTFRFDSEKLQVGQGVSLTLKTTEPGVT
GLLLAVEGPAAKRTMRPTRKDSETVDEDE-----------EVDPALTEGTIKKHTL
PF00575 // ENSGT00390000012228_0_Domain_5 (1077, 1139)
SIGD
MVTGTVKSIKPTHVVVTLKDGIIGCIHASHILDDVPEGTSPTTKLKVGKMVTARVIGGRD
MKTFKFLPISHPRFVRTVPELSVRPSELE------VGDTALNTHSVSPMEKIKEYQAGQT
VTCFLKKYNVVKKWLEVEIAPDIRGRIPLLLTSLSFKVLKHPDK-KFRIGQA-LRATVVG
PD-SSKAFLRLSL-IGSHKLEEGEVAMGRVVKVTPNEGLTISFPFGKIGTVSLFHISDSY
SETPLEDFIPQKVVRCYILSTEDSVLTLS---LRSSRTNPETKSKVEDPEINSIQDIKEG
QLLRGYVRSIQ-PHGVFFGLGPSVVGLARYPHVSQHSPSKKALYNKHLPEGKLLTARVLR
----------------LNHQKNLVELSFLPGDTGKPDVLSASLEVPLSQQEERKTEAEEK
DQKGEKKNQKRN-----K----NQKRLEE--VELPSK---------EKQQPQKPQAQ--K
RGRQEHQEPG------SEQERVSKKPKKAGPSEED----DSLLDVYYREGEEE-GEETNM
------------------------------LSKEKQTKPAEVPRLQLSSAFTWNVGLDSL
TP-ALPPLAESSDSEEDE-KPHQATQ-KKKSKKERELEKQKAEKELSRIEEALMDPGRQP
ESADDFDRLVLSSPNSSILWLQYMAFHLQATEIEKARAVAERALKTISFRE-EQEKLNVW
VALLNLENMYGSQESLTKVFERAVQYNEPLKVFLHLADIYAKSEKFQEAGELYNRMLKRF
RQEKA
PF05843 // ENSGT00390000012228_0_Domain_7 (1866, 2009)
VWIKYGAFLLRRSQAGASHRVLQRALECLPSKEHVDVIAKFAQLEFQLGDPERAK
AIFENTLTTYPKRTDVWSVYIDMTIKHGSQKDV-RDIFERVIHLSLAPKKMKFFFKRYLD
YEKQHGTEKDVQAVKAKALEYVEAKSSVED---
ENSMNEP00000035131 (view gene)
NMAALEESFPRGGTRK--IHKPEKAFQQSVEQDNLFDIS---TEEGSTKRK-KSQKGPAK
T----KKLKIEKRESSKSAREKFEILSVESLCEGMRILGCVKEVNELELVISLPNGLQGF
VQVTEICDAYTKKLNEQVTQEQPLKDLLHLPELFSPGMLVRCVVSSLGITDRGKKSVKLS
LNPKNVNRVLSAEALKPGMLLTGTVSSLEDHGYLVDIGVDGTRAFLPLLKAQEYIRQKNK
GAKLKVGQYLNCIIEKVKGNGGVVSLSVGHSEVSTAIATEEQSWTLNNLLPGLVVKAQVQ
KVTPFGLTLNFLTFFTGVVDFMHLDPKKAGTYFSNQAVRACILCVHPRTRVVRLSLRPIF
LQPGRPLTRLSCQNLGAVLDDVPVQGFFKKAGATFRLKDGVLAYARL------SHLSDSK
NVFNPEAFKPGNTHKCRIIDYSQMDELALLSLRTSIIEAQYLRYHDI
PF00575 // ENSGT00390000012228_0_Domain_1 (468, 538)
EPGAVVKGIVLTI
KSYGMLVKVGEQMRGLVPPMHLADILMKNPEKKYHIGDEVKCRVLLCDPEAKKLMMTLKK
TLVESKLPVITCYADAKPGLQTHGFIIRVKDYGCIVKFYNNVQGLVPKHELST-EYIPDP
ERVFYTGQVVKVAVLNCEPSKERMLLSFKLSSDPEPKKE--PAGHSQKKGKAINIGQLVD
VKVLEKTKDGLEVAVLPH--NIRAFLPTSHLSDHVANGPLLHHWLQAGDILHRVL---CL
SQREGHVLLCRKPALVSTVEGGQDPKNFSEIHPGMLLI
PF00575 // ENSGT00390000012228_0_Domain_4 (759, 823)
GFVKSIKDYGVFIQFPSGLSGL
APKAIMSDKFVTSTSDHFVEGQTVAAKVTNVDEEKQRMLLSL
ENSGT00390000012228_0_Linker_4_5 (823, 1077)
RLSDCALGDLATTSLLLL
SQCLEELQGVRSLMS--NR-DSVLIQTLAEMTPGMFLDLVVQEVLEDGSVVFSGGPVPDL
-VLRASRYHRTGQEVESGQKKKVVILNVDLLKLEVHVSLHQDLVNRK-AKKLRKGSEHQA
IVQHLEKSFAIASLVE--TGHLAAFSLTSHLNDTFRFDSEKLQVGQGVSLTLKTTEPGVT
GLLLAVEGPAAKRTMRPTRKDSETVDEDE-----------EVDPALTVGTVKKHTL
PF00575 // ENSGT00390000012228_0_Domain_5 (1077, 1139)
SIGD
MVTGTVKSIKPTHVVVTLEDGIIGCIHASHILDDVPEGISPTTKLKVGKTVTARVIGGRD
MKTFKFLPISHPRFVRTIPELSVRPSELE------DGHTALNTHSVSPVEKIKQYQAGQT
VTCFLKKYNVVKKWLEVEIAPDIRGRIPLLLTSLSFKVLKHPDK-KFRVGQA-LRATVVG
PD-SSKAFLCLSL-IGPHKLEEGEVAMGRVVKVTPNEGLTVSFPFGKIGTVSIFHVSDSY
SETPLEDFVPQKVVRCYILSTADSVLTLS---LRSSRTNPETKSKVEDPEINSIQDIKEG
QLLRGYVGSIQ-PHGVFFRLGPSVVGLARYSHVSQHSPSKKALYNKHLPEGKLLTARVLR
----------------LNHQKNLVELSFLPGDTGKPDLLSASLEGPLPKQEERKTEAEER
DQKGEKKNQKRN-----K-K-KNQKGQEE--VELPSK---------EKQQPQRPQAQ--K
RGGRERRESG------SEQERVSKKPKKAGPSEED----DSLMDVYYREGKEE-AEETNV
------------------------------LPKEKQTKPTEVPRLQLSSGFAWNVGLDSL
TP-ALPPLAESSDSEEDE-KPHQAMK--KKSKKERELEKQKAEKELSRIEEALMDPGRQP
ESADDFDRLVLSSPNSSILWLQYMAFHLQATEIEKARAVAERALKTISFRE-EQEKLNVW
VALLNLENMYGSQESLTKVFERAVQYNEPLKVFLHLADIYAKSEKFQEAGELYNRMLKRF
RQEKA
PF05843 // ENSGT00390000012228_0_Domain_7 (1866, 2008)
VWIKYGAFLLRRSQAGASHRVLQRALECLPSKEHVDVIAKFAQLEFQLGDAERAK
AIFENTLSTYPKRTDVWSVYIDMTIKHGSQKAV-RDIFERVIHLSLAPKRMKFFFKRYLD
YEKQHGTEKDVQAVKAKALEYVEAKSSVLED--
ENSCAFP00000015340 (view gene)
----MEESFPRGGTRKTHKLE--KAFQQSVEQDNLFDIS---IEEESTKRK-KSQKGPAK
T----KKLKIEKRESSKSVREKFEVLSVESLREGMRILGCVKEVHELELVISLPNGLQGF
VQATEICDAYTEQLNEQVAQEEPLKDLVCLSELFSPGMLVRCVVSSVGITESGKKSVKLS
LNPKNVNEVLSAEAL
PF00575 // ENSGT00390000012228_0_Domain_0 (196, 262)
KPGMLLTGTVSSLEDHGYLVDIGVSGARAFLPLQKAQEYIRQKNK
GAKLKVGQYLNCIIEEVKGNGGVVGLSIGPSEVSAAIATEEQNWTLNNLLPGLVVKAQVQ
KVTPVGLTLNFLTFFSGLVDFMHLDPKKAGTYFSNQAVRACVLCVHPRTRAVRLSLRPIF
LQPGRSLTRLSCQHLGAVLDDVPVQSFFSKAGATFRLKDGALAYARL------SHLSDSK
NIFNAEAYKPGNIHKCRIIDYSQMDEMVLLSLRPSIIESQYFRYHDIKPGALVKGTVLTI
EPYGMLVKVGEQIRGLIPPMHLADILIKNPEKKYHIGDEVKCRVLLCDPEAKKLMMTLKK
TLIESKLPAITCYADAKPGLQTH
PF00575 // ENSGT00390000012228_0_Domain_3 (564, 628)
GFILRVKDYGCIVKFYNDVQGLVPKHELSA-EYVPDP
ERVFYTGQVVKVVVLNCEPSKERMLLS
ENSGT00390000012228_0_Linker_3_4 (628, 753)
FKLLGDPK--KE--HTGHSQKKRRAISVGQLVD
VKVLEKTKDGLEVSVLPH--NIPAFLPTPHLSDHVANGPLLYHWLQAGDTLHRVL---CL
SQSEGRVLLCRKPALVSTVEGGQDPKNFAEIH
PF00575 // ENSGT00390000012228_0_Domain_4 (753, 823)
PGMLLIGFVKSIKDYGVFVQFPSGLSGL
APKAIMSDKFVTSTSDHFVEGQTVVAKVTNVDEEKQRMLLSL
ENSGT00390000012228_0_Linker_4_5 (823, 1078)
RLSDCGLGDLATTSLLLL
SQCLEERQGVRSLMS--NR-DSVLIQTLAEMTPGMVLDLEVQEVLEDGSVVFSEGPVSGL
-VLRASKYHRAGQEVEPGQKKKVVILNVDMLKLEVHVSLCHDLVNRK-PKKLKKGSEHQA
IVQHLEESFAVASLVE--TGHLAAFSLTSHLNDTFRFDSEKLQVGQGVSLTLKTTEPGMT
GFLLAVEGPAAKRTVRQTRKDSETVDEDE-----------EADPALVVGAVKKHTLS
PF00575 // ENSGT00390000012228_0_Domain_5 (1078, 1138)
IGD
MVTGTVKSIKPTHVVVTLEDGIIGCIHASHILDDVPVGTSPTAKLKVGRTVTARVIGGRD
MKTFKFLPISHPRFIRTIPELSVRPSELE-----KDGCTALNTHSSSHLEKIKQYQAGQT
LICFLKKYNVVKKWLEVEIAPDIRGRIPLLLTSLSFKVLKHPDK-KFRIGQA-LKATVVG
PD-SSKAFLCLSL-IGPHKLEKGEVAMGRVVKVTPKEGLTVSFPFGKIGKVSVFHVSDSY
SETPLEDFVPQKIVRCYVLSATGHVLTLS---LRSSRTNPETKSKITDPEINSIQDIQEG
QLLRGYVKSVQ-PHGVLFGLGPSVVGLVQYPHVSQYSPSKKTLYNRYLPEGKLLTAKVLS
----------------LKCQKNLVELSFLPNDTGKPDVFPASLGLPLLKQEERTEEAEEN
KHKEE-EK---EEKNQKRKGKRNQEGQE--GVQLPGE---------EKKEPQKLQAK--K
QGKRRRRESA------GEQERVNKKQKKAAPSEED----DSGVEVYYREGEEE-VEEMSV
------------------------------LPKEKPRRPAEVPRLQLSSGFIWDVGLDSL
TP-ALPPRGESSDSEEDN-KPQQSTQ-K-KSKKERMLEKQKAEKELSRIEEALMDPGRQP
ESADDFDRLLLSSPNSSILWLQYMAFHLQATEIEKARAVAERALKTISFRE-EQEKLNVW
VALLNLENMYGSQESLTKVFERAVQYNEPLKVFLHLADIYNKSEKFQEAGELYNRMLKRF
RQEKA
PF05843 // ENSGT00390000012228_0_Domain_7 (1866, 2008)
VWIKYGAFLLRRGQAGASHRVMQRALECLPNKEHVDVIAKFAQLEFQLGDAERAK
AIFENTLSTYPKRTDVWSVYIDMTIKHGSQKEV-RDIFERVIHLSLAPKRMKFFFKRYLD
YEKQHGTEKDVQAVKAKALEYVEAKSSVLED--
ENSCANP00000039261 (view gene)
-MATLEESFPRGGTRK--IHKPEKAFQQSVEQDNLFDIS---TEEGSTKRK-KSQKGPAK
T----KKLKIEKRESSKSAREKFEILCVESLCEGMRILGCVKEVNELELVISLPNGLQGF
VQVTEICDAYTKKLNEQVTQEQPLKDLLHLPELFSPGMLVRCVVSSLGITDRGKKSVKLS
LNPKNVNRVLSAEALKPGMLLTGTVSSLEDHGYLVDIGVDGTRAFLPLLKAQEYIRQKNK
GAKLKVGQYLNCIVEKVKGNGGVVSLSVGHSEVSTAIATEEQSWTLNNLLPGLVVKAQVQ
KVTPFGLTLNFLTFFTGVVDFMHLDPKKAGTYFSNQAVRACILCVHPRTRVVRLSLRPIF
LQPGRPLTRLSCQNLGAVLDDVPVQGFFKKAGATFRLKDGILAYARL------SHLSDSK
NVFNPEAFKPGNTHKCRIIDYSQMDELALLSLRTSIIEAQYLRYHDI
PF00575 // ENSGT00390000012228_0_Domain_1 (468, 538)
EPGAVVKGVVLTI
KSYGMLVKVGEQMRGLVPPMHLADILMKNPEKKYHIGDEVKCRVLLCDPEAKKLMMTLKK
TLVESKLPVITCYADAKPGLQTHGFIIRVKDYGCIVKFYNNVQGLVPKHELST-EYIPDP
ERVFYTGQVVKVAVLNCEPSKERMLLSFKLLSDPEPKKE--PAGHSQKKGKAINIGQLVD
VKVLEKTKDGLKVAVLPH--NIRAFLPTSHLSDHVANGPLLHHWLQAGDILHRVL---CL
SQSEGHVLLCRKPALVSTVEGGQDPKNFSEIHPGMLLI
PF00575 // ENSGT00390000012228_0_Domain_4 (759, 823)
GFVKSIKDYGVFIQFPSGLSGL
APKAIMSDKFVTSTSDHFVEGQTVAAKVTNVDEEKQRMLLSL
ENSGT00390000012228_0_Linker_4_5 (823, 1077)
RLSDCALGDLATTSLLLL
SQCLEELQGVRSLMS--NR-DSVLIQTLAEMTPGMFLDLVVQEVLEDGSVVFSGGPVPDL
-VLRASRYHRAGQEVESGQKKKVVILNVDLLKLEVHVSLLQDLVNRK-AKKLRKGSEHQA
IVQHLEKSFAVASLVE--TGHLAAFSLTSHLNDTFRFDSEKLQVGQGISLTLKTTEPGVT
GLLLAVEGPAAKRTMRPIRKDSETVDEDE-----------EVDPALTVGTIKKHTL
PF00575 // ENSGT00390000012228_0_Domain_5 (1077, 1139)
SIGD
MVTGTVKSIKPTRVVVTLEDGIIGCIHASHILDDVPEGISPTAKLKVGKTVTARVIGGRD
MKTFKFLPISHPRFVRTIPELSVRPSELE------DGHTALNTHSLSPVEKIKQYQAGQT
VTCFLKKYNVVKKWLEVEIAPDIRGRIPLLLTSLSFKVLKHPDK-KFRVGQA-LRATVVG
PD-SSKAFLCLSL-IGPHKLEEGEVAMGRVVKVTPNEGLTVSFPFGKIGTVSIFHVSDSY
SETPLEDFVPQKVVRCYILSTADSILTLS---LRSSRTNPETKSKVEDPEINSIQDIKKG
QLLRGYVGSIQ-PHGVFFRLGPSVVGLARYSHVSQHSPSKKALYNKHLPEGKLLTARVLR
----------------LNHQKNQVELSFLPGDTGKPDLLSASLEGPLPKQEERKTEAEER
HQKGEKKNQKKN-----E-K-KNQKGQEE--VELPSK---------EKQQPQKPQAQ--K
RGGRERRESG------SEQERVSKKPKKAGPSVED----DSLMDVYYREGKEE-AEETNV
------------------------------LPKEKQTKPAEVPRLQLSSGFAWNVGLDSL
TP-ALPPLAESSDSEEDE-KPHQATK--KKSKKERELEKQKAEKELSRIEEALMDPGRQP
ESADDFDRLVLSSPNSSILWLQYMAFHLQATEIEKARAVAERALKTISFRE-EQEKLNVW
VALLNLENMYGSQESLTKVFERAVQYNEPLKVFLHLADIYAKSEKFQEAGELYNRMLKRF
RQEKA
PF05843 // ENSGT00390000012228_0_Domain_7 (1866, 2008)
VWIKYGAFLLRRSQAGASRRVLQRALECLPSKEHVDVIAKFAQLEFQLGDAERAK
AIFENTLSTYPKRTDVWSVYIDMTIKHGSQKAV-RDIFERVIHLSLAPKRMKFFFKRYLD
YEKQHGTEKDVQAVKAKALEYVEAKSSVLED--
ENSAMEP00000018958 (view gene)
-TATMEESFPRGGTRKTHKSK--KALQQSVEQDNLFDIS---TEEESTKRK-KSQKGSAK
T----KKLKIEKRESSKSIREKFEILSIESLCEGMRILGCVKEVNEIELVISLPNGLRGF
VQVTEICDAYTKKLNEQVAQEEPLKDLVSLPELFSPGMLVRCVVSSVGITERGKKSVKLS
LNPKNVNEVLSAEALKPGMLLTGTVSSLEDHGYLVDIGVSGARAFLPLQKAQEYIRQKNK
GAKLKVGQYLNCIIEEVKGNGGVVGLSVVHSEVSTAIATEEQNWTLNNLLPGLVVKAQVQ
KVTPVGLTLNFLSFFTGLVDFMHLDPKKAGTYFSNQAVRACVLCVHPRTRAVRLSLRPVF
LQPGRSLTRLSCQHLGAVLDEVPVQNFFSKAGATFRLKDGALAYARL------THLADSK
NVFNAEAFKPGNTHKCRVIDYSQMDELALLSLRTSVIEAQYLKYHDIKPGALVEGTVLTI
KSYGMLVKVGEQIRGLIPPMHLADILMKNPEKKYRIGDEVKCRVLLCDPEAKKLMMTLKK
TLIESKLPAVTCYA
PF00575 // ENSGT00390000012228_0_Domain_3 (555, 629)
DAKPGLQTHGFILRVKDCGCIVKFYNDVQGLVPKHELSA-EYVPDP
ERVFYAGQVVKVVVLNCEPSKERMLLSF
ENSGT00390000012228_0_Linker_3_4 (629, 750)
RLLGDPK--KE--HPGKSQKERRTVSLGQLVD
VKVLEKTKDGLEVAVLPH--NIPAFLPTPHLSDHVANGPLLYHWLRAGDTLHKVL---CL
SQSERHVLLCRKPALVSTVEGGQDPKSFA
PF00575 // ENSGT00390000012228_0_Domain_4 (750, 823)
EIHPGMLLIGFVKSIKDYGVFVQFPSGLSGL
APKAIMSDKFVTSTSDHFVEGQTVVAKVTNVDEEKQRMLLSL
ENSGT00390000012228_0_Linker_4_5 (823, 1075)
RLSDCGLGDLATTSLLLL
SQCLEERQGVRSLMS--NR-DSVLIQTLAEMTPGMVLDLEVQEVLEDGSVAFSEGPVPGL
-VLRASKYHRAGQEVEPGQKKKVVILNVDMLKLEVHVSLCHDLVNRK-AKKLRKGSEYQA
IVQHLEESFAVASLVE--SGHLAAFSLTSHLNDTFRFDSEKLQVGQGVSLTLKTTEPGVT
GFLLAVEGPAAKRTVRQTRKDSETVDEDE-----------EADPALVVGAVKKH
PF00575 // ENSGT00390000012228_0_Domain_5 (1075, 1150)
TLSIGD
MVTGTVKSIKPTHVVVTLEDGIIGCIHASHILDDVPVGTSPTAKLKVGKTVTARVIGGRD
MKTFKFLPISHPRFIRTIPELSIRPSELE-----KDGRTALNTHSVSPLEKIKQYQAGQT
LICFLKKYNVVKKWLEVEIAPDIRGRIPLLLMSLSFKVLKHPDK-KFRIGQA-LKATVVG
PD-SSKAFLCLSL-IGPHKLEKGEVAMGRVMKVTPKEGLTVSFPFGKIGRVSIFHVSDSY
SETPLEDFVPQKVVRCYVLSVTGHVLTLS---LRSSRTNPETKSKITDPEINSIQDVQEG
QLLRGYVKCVQ-PHGVLFGLGPSVVGLARYPHVSQYSPSKKALYNRYLPEGKLLTAKVLR
----------------LNRQKNLVELSFLPSDTGKPDVFPASLGLPLLKQEEREMEAEEN
EHKEEEQKEEKEKQHQKRKGKRKQQGQE--EAQLPGR---------EKTEPQKPRAE--K
QGKRRRRESA------SEQDRVNKKQKKAAAPEED----DSGVEVYYREGEED-GEEMSV
------------------------------LPKEKPTRPAEVPRLQLSSGFVWDVGLDSL
TP-ALPPRGESSDSEDDD-KPQQSTV-K-KSKKERMLEKQKAEKELSRIEEALMDPGRQP
ESADDFDRLLLSSPNSSILWLQYMAFHLQATEIEKARAVAERALKTISFRE-EQEKLNVW
VALLNLENMYGSQESLTKVFERAVQYNEPLKVFLHLADIYTKSEKFQEAGELYNRMLKRF
RQEKAVWIKYGAFLLRRAQAGASHRVMQRALECLPNKEHVDVIAKFAQLEFQLGDAERAK
AIFENTLSTYPKRTDVWSVYIDMTIKHGSQKEV-RDIFERVIHLSLAPKRMKFFFKRYLD
YEKQHGTEKDVQAVKAKALEYVEAKSSLLED--
ENSHGLP00100025606 (view gene)
-MAALEENFPRGGTRK--IHKSEKSYQQLVEHDNLFDIS---NEEESTKRK-KNQKGPAK
T----KKLKIEKREGGKSVKEKLEILSVESLCEGMRILGCVKEVNELELVISLPNGLQGF
VQVTEICDAYTKKLNEQVAQEEPLKDLLRLPELFSPGMLVRCVVSSVSITERGKKSVKLS
LNPKNVNRVLSAEAL
PF00575 // ENSGT00390000012228_0_Domain_0 (196, 268)
KPGMLLTGTVSSLEDHGYLVDIGVVGTRAFLPLQKAQEYIRQKNK
GAKLKVGQYLNCIIEEVKSSGGVASLS
ENSGT00390000012228_0_Linker_0_1 (268, 468)
IEQSAISTAIATQEQNWSLNNLLPGLVVKAQVQ
KVTQFGLTLNFLTFFTGLVDFMHLDSKKVGTYFSNQAVRACILCVHPRTRAVRLSLRPIF
LQPGRPLTQLSCQHLGAVMKDVPVQGFFNKAGATFKLKDGALAYAR------LSHLSDSK
NAFRPETFKPGNMHKCRITDYSPMDGLALLSLRTSVIEAQYLRYHDI
PF00575 // ENSGT00390000012228_0_Domain_1 (468, 539)
KTGAVVKGTVLTM
RPFGMLVKVGEQVRGLVPATHLADILMKNPEKKYQVGAEVKCRVLLCDPEAKQLIMTLKK
TLVTSKLPVITCYEDAKPGLQTHGVIHRAKDYGCIVRFYNDVQGLVPKHELGA-QCIPDP
EKAFYAGQVVKVAVLNCEPAKERMLLSFKLLSDPEPKNE--RVGCGQKKRKDVGVGQLVD
VKVLEKTKDGLQVAVLPH--NIPAFLPTPHLSDHVANGPLVHRWLQAGDTLHRVL---CL
SQSERQVLLCRKPALVSSVEAGQDPKSFSEIQ
PF00575 // ENSGT00390000012228_0_Domain_4 (753, 823)
PGMLLVGFVKSIKDYGVFVQFPSGLSGL
APKAIMSDKFVTNPSDHFVEGQTVVAKVTNVDEEKQRMLLSL
ENSGT00390000012228_0_Linker_4_5 (823, 1077)
RLSDCRLGGPASGSLLLL
SQCLEELQGVRSLMS--SR-DSVLVQALAEMTPGMVLNLVVQEVSEDGSVVFTGAPVRDL
-VLRASRYHRAGQEVESGQKKKAVILYVDMLGLEVHVSLRKELVNRK-AWKLKKGSVHQA
TVQHLEESFAVASVGE--TGHLVAFSLASHLNDTFRFDSEKLQVGQSVCLVLKTAEPGVT
GLLLAVEGPAARRVLRQPCKDSEMGDEGE-----------GADPALAAGPRKKHGL
PF00575 // ENSGT00390000012228_0_Domain_5 (1077, 1140)
AIGD
VVTGTVKSVKPTHVVVTLEDGVMGCVHASHVLDEVPEGAAPTATLKVGKTVTARVIGGRD
VKTFKFLPISHPRFIRTVPELSVRPSELE-----KDGHTVLNTYSASPVEKIQQYRAGQT
VTCFLKKYNVVKKWLEVEIAPDIRGRIPLLLTSLSFKVLKHPDK-KFQIGQA-LRATVVG
PD-SSKPFLCLSL-IGPHKLKKGEVAMGRVVKVAPSEGLTVAFPFGRTGTVSVFHVSDSY
SERPLQDFSPQKVVRCYVLSTANHVLTLS---LRLSRTNPETKSKVEDPEINSILDIKEG
QLLRGFVRSVE-PSGVLLGLGPSVEGLARFSHVSQCSLPKKGLYSKYLPEGRLLTARVL-
---------------RLDPSKNLVELSFLPGDTGKPDVMSVSPELLVQKQEEDVEV-KER
DRKGEKKRS------PKRKEKKNQKGQE--EGELPSK---------EQVRAKRP------
-GKRERLSHLPSQES------ANKRRKKAGPPEEE----DSGVEVYYREGAEEEAAEAEV
------------------------------LPTGTLTKPAEVPRLRLSSGFFWDVGLDTL
TP-ALPPRGENSDSEEDE-KPPHATQK--KSKKERELEKQKAEKELSRIEEALRDPGRQP
ESADDFDRLVLSSPSSSILWLQYMAFHLQATEIDKARAVAERALRTISFRE-EQEKLNVW
VAL--------------KVFERAVQYNEPLKVFLHLADIYAKSEKFQEAGELYNRMLKRF
RQEKS
PF05843 // ENSGT00390000012228_0_Domain_7 (1866, 2007)
VWIKYGAFLLRRGQAGASHRVLQRALECLPAKEHMDVITKFAQLEFQLGDAERAR
AIFENMLSTYPKRTDVWSVYIDMTIKHGSQKEV-RDIFERVIHLNLAPKKMKFFFKRYLD
YEKQHGSEKDVRAVKAKALEYVEARSSVLED--
ENSFDAP00000018878 (view gene)
-MAAIEESFPRGGARK--IHKLEKSYQQSIEHDNLFDIS---SEEQSIKRK-KNQKGPAK
T----KKLKTEKRESGKSVKEKFEILSVESLCEGMRILGCVKEVNELELVVSLPNGLQGF
VQVTEICDAYTRKLNEQVVQEEPLKDLLRLPELFSPGMLVRCVVSSVSITERGKRSVKLS
LNPRNVNRVLSAEALKPGMLLTGTVSSLEDHGYVMDIGVAGTRAFLPLQKAQKYMRQKNK
GAKLKVGQYLHCVIEEVKGNGGVASLSVEQSEISAAIATREQNWSLNNLLPGLVVKAEVQ
KVTQFGLTLNFLTFFTGLVDFMHLDPKKVGTYFSNQAVRACILCVHPRTRAVRLSLRPIF
LQPGRPLTRLSCQHVGAVMKDVPVQGFFNKAGATFRLKDGSGWLRVLSLAYPRFHLSDSK
NAFRPEAFKPGNTHKCRIIDYSQMDELALLSLRTSVIEAQYLKYHDI
PF00575 // ENSGT00390000012228_0_Domain_1 (468, 539)
KTGAVVKGSVLSI
RPFGMLVKVGEQMRGLVPATHLADVLLKNPEKKYHIGDKVKCRVLLCDPEAKRLIMTLKK
TLVISKLPIIACYEDAKPGLQTHGVIHRARDYGCIVRFYNDVQGLVPKHELSA-QYVPDP
EKVFYTGQVVKVAVVNCEPAKERMLLSFKLLSDPEPKSE--SVGHGRKKEKDVGVGQLVD
VKVLEKTKDGLQVTVLPH--NIPAFLPTPHLSDHVANGPLLHHWLQAGDVLHRVL---CL
SQSERQLLLCRKPALVSSVEGGQDPKSFSEIQP
PF00575 // ENSGT00390000012228_0_Domain_4 (754, 823)
GMLLIGFVKSIKDYGVFIQFPSGLSGL
APKAIMSDKFVTNPSDHFVEGQTVVAQVTNVDEEKQRMLLSL
ENSGT00390000012228_0_Linker_4_5 (823, 1077)
RLSDCRLGGPESTSLLLL
SQCLEELQGVRSLMS--GR-DSVLVQTLAEMTPGMVLDLVVQEVSEDGCVVFCGGPVPDL
-VLRASRYHRAGQEVESGQKKKAVILNVDMLGLEVHVSLRKELVNRK-AQKLKKGSTHQA
TVQHLEPCFAVASLME--TGHLVAFSLASHLNDTFRFDSEKLQVGQGVCLVLKTTEPGVT
GLLLAVEGPAARRVLRQPRKSSETADEDE-----------EGDPALAVGPRKKHAL
PF00575 // ENSGT00390000012228_0_Domain_5 (1077, 1141)
AIGD
VVTGTVKSVKPTRVVVTLGDGVIGCVHASHILDDVPEGATPTATLRVGKTVTARVIGGRD
VKTFAFLPVSHPRFIRTVPELSVRPSELQ-----KDGYTVLNTHSASPVEKIQQYQTGQT
VTCFLKKYNVVKKWLEVDVTPDIRGRIPLLLTSLSFKVLKHPDK-KFQIGQA-LRATVVG
PD-SSKAFLCLSL-IGPHKLEKGEVAMGRVVKVTPGKGLTVAFPFGRTGTVSIFHVSDSY
SERPLEDFIPQKVVRCYVLSTAGHVLTLS---LRSSRTNPETKSKVEDPEISSMRDVKEG
QLLRGYVRSVE-PSGVLLGLGPSVEGLALFSHVSRCGLPRRDLYSKYLPEGRLLTARVL-
---------------RLNPSENLVELSFLPGDTGQPDVLSVSPELLLQKQKEEVGA-KER
DKMGEKKRS------QKRT-EKNQEGLE--EGELPSK---------EQVGAKRS------
-GKRERPDSGEAQES------VNKRQKKAGPPE-D----DSGVEVYYREGEEE----TEV
------------------------------LLKGTLTKPADAPRLRLSSGFLWDVGLDTL
TP-ALPPRRESSDSEEDE-EPHHATQK-RKSKKERELEKQKAEKELSRIEEDLRDPGRQP
ASADDFDRLVLSSPNSSILWLQYMAFHLQATEIEKARAVAERALKTISFRE-EQEKLNVW
VALLNLENMYGSPESLSKVFERAVQYNEPLKVFLHLADIYAKSEKFQEAGELYNRMLKRF
RQEKA
PF05843 // ENSGT00390000012228_0_Domain_7 (1866, 2006)
VWIKYGAFLLRRGQAGASHRVLQRALECLPAKEHLDTITKFAQLEFRLGDAERAR
AIFENVLSTYPKRTDIWSVYIDMTIKHGSQKEV-RDIFERVIHLSLAPKKMKFFFKRYLD
YEKQHGTEKDVRAVKAKALEYVEAKSSALED--
ENSOPRP00000009706 (view gene)
-MAALEENFPRGGTRKKSDHKSEKSFQQAAEQDNLFDVS---NEEKSSKRK-KSQKEPVI
P----KKFKTEEREKNKSVTEKFEILSVESLCEGMRILGCVKEVNELELVISLPNGLQGY
VQVTEICNAYTEKLTEQMAQEEPLKDLPRLPELFSPGMLVRCVVSSLAVTEKGKKSIKLS
LNPKNVNRVLSAEALKPGMLLTGTVSSLEDHGYLMDIGVSGTRAFLPLQKAQEYIRQKNK
GANLKVGHYLHCIIEEVKGDGGVVSLSVGNTEVSTAIASEEQSWTLNNLLPGLVVKAQVQ
KVTRFGLMLNFLTFFTGTVDFMHLDPKKVGTYFSNQAVRACILWVHPQSRGVRLSLRPXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXL------NHLSDSK
KVFRPEVFKPGNTHKCRI-DYSP---DLILSLRTSVIEAQYLRYH
PF00575 // ENSGT00390000012228_0_Domain_1 (466, 539)
DIKPGAVIKGTVLTI
KPYGILLKVGEQIRGLVPANHLADVFMKNPEKKYHVGEELKCRVLLCDPEAKKLIMTLKK
TLVESKLPAITCYDDAKPGLQTHGVITRVKDYGCLVKFYNDVQGLVPKHELSA-EYIPDP
ENIFYSGQVVKVVVLNCEPSKERMLLSFKLLSN-----------------------TLVD
VKVLEKTKDGLEVAVLPH--NIPAFLPTAHLSDHVANGPLLHHWLQAGDILHGVL---CL
SQSEKHILLCRKPALVSTVEGGQSPKNFS
PF00575 // ENSGT00390000012228_0_Domain_4 (750, 823)
EIHPGMLLIGFVKSIKDYGVFVQFPSGLSGL
APKAIMSDKFVTTPSDHFVEGQTVVAKVTNVDEEKQRMLLSL
ENSGT00390000012228_0_Linker_4_5 (823, 1075)
RLSDCMLGNVASTSLLLL
SQCLEELQGVRSLMS--NQ-DSVLIQTLAKMTPGMILDLAVQEVLEDGSVLFSEGPVPGL
-VLRASKYHRAGQKVKSGQKKKVVVLNVDMLKLEVHVSLFQNLVERK-AKKLKRGSEHQA
IVEHLEESFAIASLVG--TGHLAAFSLTSHLNDTFRFDSEKLQVGQGVSLTLKTTEPGVT
GFLLAVEGPAAKRTMRQSRKDSETVDEDE-----------EMDPALTVGSLKKH
PF00575 // ENSGT00390000012228_0_Domain_5 (1075, 1150)
TLSIGD
KVTGTVKAVKATHVVVTLEDGIIGCIHASHILDDVPVGTSPTSTLKVGKTVTARVIGGRD
VKTFKFLPISHPRFIRTIPELSVRPSELA-----KDGHTALNTYSDSPVEKIKQYQAGQT
VTCFLKKYNMVKKWLEVEIAPDIRGRIPLLLTSLSFKVLKRPDK-KFQVGQA-LKATVVG
PD-SSKAFLCLSL-IGPHKLEEGAVAMGRVVKVTPNKGLIVSFPFGRKGRVSMFHVSDSY
SETPLQDFTPRKVVRCYILSAEKPVLALS---LRLSRTNPETKSKVEDPEIDSIRDVREG
QLLRGYVRSVQ-PSGVFLGLGPSVMGFADYPHVSQYEPSEKDLYDKYLPEGKLLTAKVLR
----------------LNYQQDLVELSFLPGDTGKPDIFPASLELPLLKQGKRRKAEE-K
CQKREGKEQKNN-------EKKDLQGQ-Q-EAQLPSK---------EPGELPRPPGK--G
QGKRERRESG------NEQERGNKKPKKAGPSEES----DSGVEVYYREGEEE-LEAADV
------------------------------LPK-KPTRPAEAPRLQLSSGFAWNVGLDSL
TP-ALPPQGDSSDSEEDE-KPRPTT---KKSKKERELEKQKAEKELSRIEEALMDPGRQP
ESADEFDRLVLSSPNSSILWLQYMAFHLQATEIEKARAVAERALKTISFRE-EQEKLNVW
VALLNLENMYGSRESLDKVFERALQYNEPLKVFLHLADIYTKSEKFQEATELYNRMLKRF
RQEKAIWIKYGAFLLRRSQAGASHRALQRALECLPSKDHVDVIVKFAQLEFQLGDAERAK
AMFENTLSTYPKRTDVWSVYIDMTIKHSSQKEV-RDIFERVIHLSLAPKRMKFFFKRYLD
YEKQHGTEKDVQAVKAKALEYVEARSSVMED--
ENSACAP00000004780 (view gene)
-MSSLEENFPRGGTQKKRQEG-NTPRSQTIDQDNLFQAQ---NEEVTRKRK-KKHQDQAE
P----KKLKSDERAALKINAKDFELLTAESLTDGMLLLGCVKEAHQLELVISLPNGLTGF
VQVTQICDAYNKILNTQVATDEHLEDLSSLSDLFFPGMVVRCAVVNLEKTKAGRRSIQLS
VNPKDVNKALNSSTLRPGMLLSGCIASVEDHGYLIDIGVPAAKAFLPRQKAQGYLQSNNK
GAELKIGQYLNCLIEDVKNNGRIIRISISQAEIAAAIATEEQNWSLSNLLPGLVVKAQVR
EVTPSGMSLGFLSSFTGIVDFMHKNHLKGRTYSPGEMVKACILSNNPTTKAIRLSLRPAF
LQPGTQLSQLCSDRIGMIVENSKVKTFLSKTGAIFVLDDGSLGFAHQ------KHLSDSR
LSFKPEKFKPGNEHKCRIIEYSLMDDMALLSLKQNIMDAPFLKYQDI
PF00575 // ENSGT00390000012228_0_Domain_1 (468, 539)
HPGQVLEGTILTL
KPFGMHVKLTEYIKGLVPCLHLADVPLKQPEKKYSEGASVKCRVLVSIPEARKIVLTLKK
TLVNSKLPILASYEDAKPGLITHGFVVCAREFGCIVKFYNDIKGLVPKNELGL-PPLTPP
QEVFYEGQVVKVMVLKCEPEQGKVLLSFNLTDNPLDKTGRGE-KTSKKQEKIYENAQVAD
VKILKKKDDGLDITILPN--NISAYLPMMHLSDYVSHSKLWSHWLKEDDLLHSVV---CL
HSKGRHLTLSRKPTLVLAAQEEHAVKNFSDL
PF00575 // ENSGT00390000012228_0_Domain_4 (752, 823)
EPGLLLTGFVKNIMPYGVFVEFPYGLTGM
APKSAMSDKFVTDTKDHFVIGQTVIAKVTNIDEEKQRILLSL
ENSGT00390000012228_0_Linker_4_5 (823, 1078)
KLSDCSSEDSVSQSFSLL
LQYFKELQEIKSIMK--KRDDSSVAQRLCEIKPAQKLELVVHKVETDGSAVFRGTCADGL
-TVVAAHSHLGGKNVAVGEKAEAVVLYIDYLKAKIYVSLREELLSSK-PKKLTLDSQYEA
IVQHVATEYSVASLIG--TGQLIAIPVTSHFNDTFRFDSEKLKMGQSVMVVLKMVERGDY
GLLLAVQAPGKRMTAIRSRRDSEAL--------------------EETLPTVKHSLC
PF00575 // ENSGT00390000012228_0_Domain_5 (1078, 1141)
VGD
VVKGTVKSVKPTHVLVAIDDHLMGSIHASQIVDDVFEGTFPTSLLKVGQKVTARVIGGRE
IRTHRYLPITHPHFTQTWPELSVRPSELK-----GENKTVLGPEDDKSEETLKLFKPGQT
VTCFVKKYNTEKKWLEVEVTPDIRGRIHELLLSLKPKILKKPGN-FFKTGQA-LIATVTG
CDTTGT-KVYLSL-SGVYSLEKGTITLGCIKSVIPHVGLQVTLPFGRTGKVSLFHLSDSY
TEQPLEDFSVGKIVRCYVLSDEDKTIKLS---LRQSRVSPKSHNKIEDPEIASLDNIKKD
QLIRGYVKSIT-ATGILFRLSDSVVGCIPLQRITPVCVPDHSLCAKYIHPGQLLTAKVFS
----------------INKAENLVELSLLPEDTGNPSIIPELCSSETN--------TNLM
KTR---------------------------------------------------------
--KRKRRNSENE----Q---QQVKPKKRVHCTEDD----DSGVEIYCREEEEEEK-Y---
--------------------------------GRKSKQRKEISRLKISTSFTWEEGLNVL
NTAMLKPKEQSSDSEEEDD-TETTTK--KQTKKQRELEKQKAEKELSKLEAALMDPNRKP
QTADDFDRLVLSNPDSSILWLQYMAFHLQATEIEKARAVAERALKTISFRE-EQEKLNVW
VALLNLENMYGTEEALMKVFERAIQYNEPLKVFQQLADIYTGSEKYKEADDLYNTMLKRF
RQEKSVWVKYSTFLLKRGLLEAAHRLLPRALKCLPEKEHVDVIS
PF05843 // ENSGT00390000012228_0_Domain_7 (1905, 2004)
KLAQLEFQFGDSEHGK
AIFENTLSTYPKRTDIWSVYIDMIIKHGSQKEV-RDIFERVIHLSLAAKKMKFFFKRYLE
YEKKYGTAETVQVVKAAALEYVESKGGLAEH--
ENSPSIP00000005483 (view gene)
-MESMEENFPRGGTQKKSVQ--GKAPRQPIEQDNLFDTC---HEEGSQKRK-RIHDDQGK
Q----KKLKAEKKEAIKTNAKDFELLTVEALSEGMLLGGCVKESNDFELVVSLPNGLVGF
VQVTHVCDAYSKMLNEQVVREELLEDLNSLSDLYPPGMLVRCHVSSVEKTTEGRQSVKLS
INPKDVNKALNPTALR
PF00575 // ENSGT00390000012228_0_Domain_0 (197, 268)
SGMLLSGLVSSVEDHGYLVDIGVSGAKAFLPRQKSQSYLKSANK
GAELKIGQYLNCLIEEVKNNGRIVRLS
ENSGT00390000012228_0_Linker_0_1 (268, 470)
VHQSEVAAAIATEEQNWTFSNLLPGLVVKAQVQ
KVTPYGLTLGFLSSFTGIVDFMHLDPKKGRNYTESQMVKACVLSVHPTSKVVRLTLRQSF
LQPGGVLSQLSSGRIGTVVEEAVVKSFHPKAGAVFELDDGTLAFARL------KHLSDTK
KSFRPGAFRMGSKHRCRIIDYSLMDELALLSLKRRIIAAPFLRYQDICP
PF00575 // ENSGT00390000012228_0_Domain_1 (470, 539)
GHVVEGKVLAL
KPFGMQVKVTDHIRGLVPHLHLADVLLKHPEKKYSVGDEVKCRVLISQPEEKKLLLTLKK
TLVTSKLPVLASYEAAKPGLMAHGFVVCAREFGCIVKFYNDVKGLVPKNELSS-EPVPSP
EKAFYAGQVVKVIVLKCEPEQERLLLSFKLTSRAASGDGGEH-VPKKNRDVTYQTGQMVD
VKVLKKKDNGLEVSILSD--NVSAHLPTMHLSDHVVSCKLLYRWLQEGDILHKVM---CL
SDKGGHVTLCRKPAVISAVQEEQVVRSFSEI
PF00575 // ENSGT00390000012228_0_Domain_4 (752, 823)
QPGMQLIGYVRNIMSYGVFVEFPFGLAGL
APKSAMSDKFVTDPKDHFEVGQTVVAKVTSMDEEKQRILLCL
ENSGT00390000012228_0_Linker_4_5 (823, 1076)
KLSEVGLEDPVTGSFSLL
SRCLEEMKEIRGVMS--KRNHSKVAQNLCGLIPGKKLHLVVQEVKADGSAFFNGT-----
----ATRYHVGDKSLVAGQKARVLVLHVDALQCVVHVSLREELLNPK-AQRLKENSQHTA
VVQHVAEEFAVASLVE--AGQLTAIPVASHFNDTFRFDSEKLKVGQTVSVTLKTVQTGDW
GVLLAVQGPAKKRAFVRSRKESETVEE------------------ALL--AMKHS
PF00575 // ENSGT00390000012228_0_Domain_5 (1076, 1138)
LRVGD
MVTGTVKSVRPTAVTVAIDDKITGSIHVSRVLDEVPVGTFPTSRLKAGQQVTARVIGGKD
VKTHRYLPITHPHFTQSVPELSIRPSDLK-----GDGSPAPRPSGDSPSERLGPYKAGQT
VTCFVKKYNTIKTWLEVEVAPEVRGRVPQLLLSLNPKVLKHPEK-SFKNGQA-LSATVTG
TDASKT-NLFLSL-IGAHSLVEGTITLGTIMKVTPHVGLTIALPFGKTGKAGIFHLSDSY
SEQPVENFSVGKHVRCCVLCNKDNKIEVS---LRQSRTNPKSKNKVEDPEITSVEDVREG
QLVRGYVRSVK-QSGVFFGLSSSVVGRVQFHNVVPFFVPKQSLYEQYLPEGKLLTAKVLS
----------------VNNKESHVELSLLPADTGKPGVLPEQLGLPLCDTDKEKAAE---
----F-----KKLKAKR--KRGDSEGEQVGVCRRLVSLLGVGCWADRESRNAFPLLLSCF
TSKR---GMVGD----QKPATFNRHRRDICAAQRK----ELCLPQS------GVNE--IA
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
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---------------------------------
MGP_SPRETEiJ_P0051076 (view gene)
-MANLEESFPRGGTRK--LHKSEKSSRQVVEQDNLFDVS---TEEGPIKRK-KGQKGPAK
T----KKLKIEKRKSIKSIKEKFEILSLESLCEGMRILGCVKEVSELELVVSLPNGLQGF
VQVTEVCDAYTQKLNEQVAQEEPLEDLLRLPELFSPGMLVRCVVSSLDVTESGKKSVKLS
VNPKRVNKVLSAEALR
PF00575 // ENSGT00390000012228_0_Domain_0 (197, 268)
PGMLLTGTVSSLEDHGYLVDIGVGGTRAFLSLKKAQEYIRQKNK
GAKFKVGQYLTCVVEEVKSNGGVVSLSVEHSEVSSAFATEEQSWNLNNLLPGLLVKAQVQ
KVTQFGLQLNFLTFFKGLVDFMHLEPKKMGSYSSNQTVKACILCVHPRTRVVRLSLRPIF
LHPGRPLTRISYQQLGAVLDDVPVQGFFKNAGAIFRLKDGVLAYARV------SHLSDSK
KAFNAEAFKPGSTHKCRIIDYSQMDELALLSLRKSIIAAPFLRYHDIKIGTVVKGTVLAI
KPFGILVKVGEQIKGLVPSMHLTDIMMKNPEKKYSPGDEVKCRVLLCDPEAKKLIMTLKK
TLVTSKLPLITCYEGAKPGLQT
PF00575 // ENSGT00390000012228_0_Domain_3 (563, 628)
HGVIIRVKDYGCVVKFYNHVQGLVPKHELST-QHIPDP
EAVFYTGQVVKVAVLSCEPSKERMLLS
ENSGT00390000012228_0_Linker_3_4 (628, 754)
FRLLSDSGPKDP--SVENSQKKTGAVNIGQLVD
VKVLEKTKTGLEVAILPH--NTPAFLPTPHLSDHAANGPLLHHWLQTGDTLHRVL---CL
SQSERHILLCRKPALVSTVEGGQDPKSLSEIQP
PF00575 // ENSGT00390000012228_0_Domain_4 (754, 823)
GMLLIGFVKCIKEYGVFVQFPSGLSGL
SPKTIMSDKFVTTPSEHFVEGQTVVAKVTNVDESKQRMLLSLRLSDCSLGDSASTSFLLL
CQCLEELQGIRSLMS--NQ-DSVLIQTLADMTPGMVLDAVVHEVLEDGSVVFSSDPVPDL
-VLRASKYHRAGQEVEPGQKKKVVVLHVDMLKLEVHVSLHQDLVNRK-PRKLRKSSRHQG
IVQHLEESFAVASLVE--TGHLVAFSLISHLNDTFHFDSEKLHVGQGVCLTLKTTEPGVT
GLILAVEGPASKRTRMPVQRDSETVDDKGEEKEEE--EEEKEEENLTVKSKKRHSLAIGD
KVTGTIKAVKATHVVVTLADGFVGCIHASRILDDVPVGTSPTTTLKAGKKVTARVIGGRD
VKTSKFLPISHPRFVLTILELSVRPSELK-----G-SYSALNTHSESPVEKIRQYQAGQT
VTCFFKKYNVMKKWLEVDIGPDIRGRIPLLLTSLSFKVLKHPDK-KFQVGQA-IEATVVD
PD-VPRAFLCLSL-IGPYRLEEGEVAMGRVMKVVPNRGLTVSFPFGKIGKVSMFHLSDSY
SEAPLEDFCPQKIVRCYILSTAHRVLALS---LRSSRTNRETKNRIEDPEINSIEDVKEG
QLLRGYVKCVL-PSSVIIGLGPSVLGLAKYSHVSECVPPEKELYNRCLPEGKLVTAKVLC
----------------VNPMKNLIELSLLPSDTGRPDVFSPAPEP---KQEERRGGAEE-
GQKRK--EKN-------------Q---------KRRE---------EKEEPQKSQRG--G
RGKRERQESE------SEQELVNKRPKKSGAAEED----DSGVEVYYREGEDE-VGEPKL
------------------------------PPRGKQTKPTEVPRLHLSSGFLWDVGLDSL
TP-ALPLREESSDSED--EQPHQAKK--KKGKKERELEKQKAEKELSRIEEALMDPGRQP
ESADDFDRLVLSSPNSSILWLQYMAFHLQATEIEKARAVAERALKTISFRE-EQEKLNVW
VALLNLENMYGSQESLTKVFERAVQYNEPLKVFLHLADIYTKSEKFKEAGELYNRMLKRF
RQEKAVWIKYGAFVLGRSQAGASHRVLQRALECLPAK
PF05843 // ENSGT00390000012228_0_Domain_7 (1898, 2006)
EHVDVIVKFAQLEFQLGDVERAK
AIFENTLSTYPKRTDVWSVYIDMTIKHGSQTAV-RDIFERVIHLSLAPKRMKFFFKRYLD
YEKQHGTEKDVQAVKAKALEYVEAKSSALED--
ENSSTOP00000013072 (view gene)
-MATVEESFPRGGTRK--THKLEKSFQESVEQDNLFDIS---TEEESTKRK-KSQKGPVK
T----KKLKIEKKENSKSIKEKFEILSVESLCEGMRILGCVKEVNELELVISLPNGLQGF
VQVTEISDDYTKMLNEQVAQEDPLKDLLRLPELFSPGMLVRCVVSSLRITERGKKSVKLS
LNPKNVNRVLSAEAL
PF00575 // ENSGT00390000012228_0_Domain_0 (196, 268)
KPGMLLTGTVSSLEDHGYLVDIGVGGTRAFLPLQKAQDYIQQKNK
GAKLKVGQYLNCVIEEVKSNGGVVSLSIGHSEVSTAIATEEQNWTLNNLLPGLVVKAQVQ
KVTQFGLRLNFLTFFTGLVDFMHLEPKKVGTYFSNQAVRACILCVHPRTRVVRLSLRPIF
LQPGRPLTRLSCQHLGAVLDDVPVQGFFNKAGATFRLKDGALAYARL------SHLSDSK
KVFSPEAFKPGNTHKCRIIDYSQMDELALLSLRTSIIEAQYLGYHDIKTGSVVKGKVLTI
KPFGILVKVGEQMRGLVPAMHLADILMKNPEKKYHIGDEVKCRVLLCDPEAKKLVMTLKK
TLVTSKLPAVTCYGDAKPGLQT
PF00575 // ENSGT00390000012228_0_Domain_3 (563, 628)
HGVIIRVKDYGCIVKFYNDVQGLVPKHELSA-QYIPDP
ERVFYIGQVVKVTVLNCEPSKERMLLS
ENSGT00390000012228_0_Linker_3_4 (628, 754)
FKLLSNPEPENEKESVGHGQKTGR-----QVVD
VKVLEKTKDGLQVAVLPH--NIPAFLPTPHLSDHVANGPLLYRWLQAGDTLHRVL---CL
SQSEKHVLLCRKPSLVSSVEGGQDPNSFSEIHT
PF00575 // ENSGT00390000012228_0_Domain_4 (754, 823)
GMLLIGFVKSIKDYGVFVQFPSGLSGL
APKAIMSDKFVTNPSDHFVEGQTVVAKVTNVDEEKQRMLLSL
ENSGT00390000012228_0_Linker_4_5 (823, 1078)
RLSDCTLGEPASTSLLLL
SQCLEELQGVRSLMS--NQ-DSVLIQTLAEMTPGMVLDLVVQEVLEDGSVVFSGGPVPDL
-VLRASKYHRAGQEVESGQKKKVVILNVDMLKLEVHVSLCQELVNRK-SKKLKKGSKHQA
IVQHLEESFAVASLVE--TGHLVAFSLTSHLNDTFRFDSEKLQVGQGVCLTLKTTEPGVT
GLLLAVEGPAAKRTMRETRKDSETVDEDE-----------EGDPSLTGGTKKKHTFV
PF00575 // ENSGT00390000012228_0_Domain_5 (1078, 1140)
IGD
IVTGTVKSVKPTHVVVTLEDGIVGCIHASHILDDVPVGTSPTTKLKVGKTITARVIGGRD
VKTFKFLPISHPRFVRTILELSVRPSELE-----EDGHTALNTYSASLMEKIKQYHAGQI
VTCFLKRYNVVKKWLEVEIAPDIRGRIPLLLTSLSFKVLKHPDK-KFQIGQA-LRATVVG
PD-SSKAFLCLSL-IGPHKLEKGDVAMGRVVKVTPNKGLTVSFPFGRMGRVSIFHVSDSY
SETPLKDFIPQKVVRCYVLSTGDHVLTLS---LRLSRTNPETKSKVEDPEIDSIQDVKEG
QLLRGYVRTCL-SP---SSLGPSVVGLAQYSHVSQCNLPNKDLYHEYLPEGKLLTAKVLS
----------------LNHQKNLVELSFLPRDTGKPDVFSTPLELPLLKQKEGKIETEKQ
DQKGEKKEKNNQK---RK-ETKNQKG----------------------------IQL-GA
GGDTWAFSHL------TSQERANKR-QKTGLAEED----DSGVEVYYREGEEE-IEETK-
---------------------------------GRLTKPADVPRLQLSSGFIWNVGLDSL
TP-ALPPQGESSDSEEDE-KPHQATK--KKSKKERELEKQKAEKELSRIEQALMDPGRQP
ESADDFDRLVLSSPNSSILWLQYMAFHLQATEIEKARAVAERALKTISFRE-EQEKLNVW
VALLNLENMYGSQESLTKVFERAVQYNEPLKVFLHLADIYTKSEKFQEAGELYNRMLKRF
RQEKA
PF05843 // ENSGT00390000012228_0_Domain_7 (1866, 2008)
VWIKYGAFLLRRSQAGASHRVLQRALECLPTKEHVDVIAKFAQLEFQLGDAERAK
AIFENTLSTYPKRTDVWSVYIDMTIKHGSQKEV-RDIFERVIHLSLAPKRMKFFFKRYLD
YEKQHGTEKDVQAVKAKALEYVEAKSSVLDD--
ENSNLEP00000024355 (view gene)
-MANLEESFPRGGTRK--IHKPEKAFQQSVEQDNLFDIS---TEEGSTKRK-KSQKGPAK
T----KKLKIEKRESIKSAREKFEILSVESLCEGMRILGCVKEVNELELVISLPNGLKGF
VQVTEICDAYTKKLNEQVTQEQPLKDLLHLPELFSPGMLVRCVVSSLGITDRGKKSVKLS
LNPKNVNRVLSAEALKPGMLLTGTVSSLEDHGYLVDIGVDGTRAFLPLLKAQEYIRQKNK
GAKLKVGQYLNCIVEKVKGNGGVVSLSTGHSEVSTAIATEEQSWNLNNLLPGLVVKAQVQ
KVTPFGLTLNFLTFFTGVVDFM-----------------ACILCIHPRTRVVRLSLRPIF
LQPGRPLTRLSCQNFGAVLDDVPVQGFFKKAGATFRLKDGVLAYARL------SHLSDSK
NVFNPEAFKPGNTHKCRIIDYSQMDELALLSLRTSIIEAQYLRYHDIQPGAVVKGTVLTI
KSYGMLVKVGEQMRGLVPPMHLADILMKNPEKKYHIGDEVKCRVLLCDPEAKKLMMTLKK
TLIESKLPVITCYADAKPGLQTH
PF00575 // ENSGT00390000012228_0_Domain_3 (564, 628)
GFIIRVKDYGCIVKFYNNVQGLVPKHELST-EYIPDP
ERVFYTGQVVKVAVLNCEPSKERMLLS
ENSGT00390000012228_0_Linker_3_4 (628, 759)
FKLSSDPEPKKE--PAGHSQKKGKAINIGQVRG
LLWT---------------------------------SYFMLQWQRG-------------
VVEDCVMLLCRKPALVSTVEGGQDPKNFSEIHPGMLLI
PF00575 // ENSGT00390000012228_0_Domain_4 (759, 823)
GFVKSIKDYGVFIQFPSGLSGL
APKAIMSDKFVTSTSDHFVEGQTVAAKVTNVDEEKQRMLLSL
ENSGT00390000012228_0_Linker_4_5 (823, 1077)
RLSDCGLGDLATTSLLLL
SQCLEELQGVRSLMS--NR-DSVLIQTLAEMTPGMFLDLVVQEVLEDGSVVFSGGPVPDL
-VLRASRYHRAGQEVESGQKKKVVILNVDLLKLEVHVSLHQDLVNRK-AKKLRKGSEHQA
IVQHLEKSFAIASLVE--TGHLAAFSLSSHLNDTFRFDSEKLQVGQGVSLTLKTTEPGVT
GLLLAVEGPAAKRTMRPTRKDSETVDEDE-----------EVDPSLTVGTIKKHTL
PF00575 // ENSGT00390000012228_0_Domain_5 (1077, 1139)
SIGD
MVTGTVKSIKPTHVVVTLEDGIIGCIHASHILDDVPEGTSPTTKLKVGKTVTARVIGGRD
MKTFKYLPISHPRFVRTIPELSVRPSELE------DGHTALNTHSVSPVEKIKQYQAGQT
VTCFLKKYNVVKKWLEVEIAPDIRGRIPLLLTSLSFKVLKHPDK-KFRVGQA-LRATVVG
PD-SSKAFLCLSL-IGPHKLEEGEVAMGRVVKVTPNEGLTVSFPFGKIGTASIFHMSDSY
SETPLEDFVPQKVVRCYILSTADNVLTLS---LRSSRTNPETKSKVEDPEINSIQDIKEG
QLLRGYVGSIQ-PHGVFFRLGPSVVGLARYSNVSQHSPSKKALYNKHLPEGKLLTARVLR
----------------LNHQKNLVELSFLPGDTGKPDVLSASLEGPLPKQEERKTEAEER
DQKGEKKNQKRN-----E-K-KNQKGQEE--VELPSK---------EKQQPQKPQVQ--K
RGRRERRESG------SEQERVSKKPKKAGLSEED----DSLVDVYYREGKEE-AEETNV
------------------------------LPKEKQTKPAEVPRLQLSSGFAWNARLDSL
TP-ALPPLAESSDSEEDE-KPHQATK--KKSKKERELEKQKAEKELSRIEEALMDPGRQP
ESADDFDRLVLSSPNSSILWLQYMAFHLQATEIEKARAVAERALKTISFRE-EQEKLNVW
VALLNLENMYGSQESLTKVFERAVQYNEPLKVFLHLADIYTKSEKFQEAGELYNRMLKRF
RQEKA
PF05843 // ENSGT00390000012228_0_Domain_7 (1866, 2008)
VWIKYGAFLLRRSQAGASHRVLQRALECLPSKEHVDVIAKFAQLEFQLGDAERAK
AIFENTLSTYPKRTDVWSVYIDMTIKHGSQKDV-RDIFERVIHLSLAPKRMKFFFKRYLD
YEKQHGTEKDVQAVKAKALEYVEAKSSVLED--
ENSAPLP00000010117 (view gene)
-MASIEENFPRGGIQKKPTEKTGKAPKPTTEQDNLFDVR---HEEQSQKRK-RNQEDLGK
R----KKFKADRKAGAKDNTMNIEPLTIEHLCEGMLLLGCIKEVSDFELVISLPNGLTGF
VPVTQISDAYSKMLSKQVAQGEVLEDLHSLLDMYSPGMLVRCIVTSVEKSADGRRSIKLS
INPKNVNRGLNASALTSGMLLSGFVSSAEDHGYLIDIGVNGTHAFLPRQKAQNYIKAVKR
GPDLKIGQNLNCVIEQVKNEGRIVRLSVDRSEVAASLATEQQNWTLSNLLPGLVVKAKVQ
KVDPLGISLTFLSSFTGIVDFMHVDPDKSINYSPNQVVKACILSVHPTSKVVRLTLRQSF
LNPGGSPNQLSNDRIGAVVEESTVKAFYKQFGAIFELDDGTHAFARL------KHLSKNR
KSFKPAAFKAGCKHKCRIIDYSLMDEMCILSLKYQVIGARFLQYQ
PF00575 // ENSGT00390000012228_0_Domain_1 (466, 539)
DIHTGDVVQGRVLAL
KPIGMQVKVTDGIKGLVPSLHLADVILKQPEKKYNVGDEVKCRVLECNPAEKKLFLTLKK
TLIQSKLPILSKYEDAEPGLITHGFVVCAREFGCIVKFYNDVKGLVPKNELSA-EPISCP
DKVFQEGQVVKVMVLKCEPEQERLLLSFKLSSTSAPEGKSEH-TPKKKQEVKYQIGEMVD
VKVLKKKENGLEVSILEDEGNVIASLPTVYLSDFVANCKLLWHCLQEGDVLPRVM---CL
SDKGDRIILCRKSAVISAVQEEQVVRNFS
PF00575 // ENSGT00390000012228_0_Domain_4 (750, 823)
EIQPGMLLTGYVRNVMHFGVFVEFPFGVTGL
APKVSMSDKFVTDTKDHFVVGQTVIAKVMSTDEEKQRVLLNL
ENSGT00390000012228_0_Linker_4_5 (823, 1075)
KVSECSSGNPAAESFSLL
NQYFKEVKEIRNLLK--RR-ESGIARSLCELMPGKELQLVVQDVKEDGSALFSGSCVKGL
-TVTATRYHLGDKSIAPGEKTKGLVLHVDVLTSKVYVSLREELLKQRPKQQLKENSQHSA
IVQHIAEEFAIVSL-E--TGQLAAIPIASHFNDTFRFDSEKLKVGQTIYATLKMVKVNDH
GVVLAVQDPAKKNVFVRVRKESETTLE------------------EMLAAAVTH
PF00575 // ENSGT00390000012228_0_Domain_5 (1075, 1145)
SLSVGD
IVTGTVKSVKPTHVTVAIDDKLTGSIHASRILDEVPIDSFPTHTLKAGQKVTARVIGGRD
VNTH
ENSGT00390000012228_0_Linker_5_6 (1145, 1279)
RYLPITHPHFTRSIPELSIRPSEIE-----GKAETL--KDGT--LKKPELYNVGQT
VTCFVKKYNVLKNWLEVEVSPDIRGRVPHLMLSPSTKVLKHPEK-NFKNGQA-LSATVTG
TGVTET-NLFLSLIAGIP
PF00575 // ENSGT00390000012228_0_Domain_6 (1279, 1354)
SLQQGTITVGVIAKMIPHVGLTITLPGGKTGKVSIFHLSDKY
TENPLSDFKVGKVVRCYILANENGKIQLS---LRQSRLNPRNSSKVEDPEIMSTKDVKKG
QLVRGYVKSVT-PSGVFFGLSASLQGRILFQNVSIYYVQKHSLYEKYLPEGKFLTAKVLG
----------------VNKKENHIELSLLPEDTGMPSVLPESLGLPRYSAHKLKTKRRRK
SSEIE-----QV---QE--KRLNYIGD----QQVQKLILL--AY--VG-KSEFL--LLCP
SYE-----S-IE----AK-----PKKRKVCPTDEN----DSGIEVYYREEEDGDQEEEAA
E-----------------------------NKSKQIRKRGEAPRLQVSTGFTWDEDMKAV
DMAVLNQKEESSESEDEEENPQSKK---KHQKYSSILLKSCSSHLLEKLEAALMDPSRQP
QSADDFDRLVLSSPDSSILWLQYMAFHLQATEIEKARAVAERALKTICFRE-EQEKLNVW
VALLNLENMYGTEETLMKVFERAVQYNEPLKVFQHLCDIYANSEKYKQAEELYHTMLRRF
RQEKSVWLKYASFLLKQGQTEATHRLLERALKALPTKEHVDVISRFAQLEFRFGDTEHAK
ALFDSTLNSYPKRTDIWSIYMDIMIKHGSQKEV-RDIFEKVIHLNLAPKKMKFFFKRYLD
YEKKYGTEETILAVKTAALEYVEAKSSLADA--
ENSCCAP00000003807 (view gene)
-MATLEESFPRGGTRK--IHKPEKAFQQSVDQDNLFDIS---TEEGSTKRK-KSQKLPAK
T----KKLKIEKRESSKSAREKFEILSVESLCEGMRILGCVKEVNELELVISLPNGLQGF
VQVTEICDAYTEKLNEQVTQEQPLKDLLHLPELFSPGMLVRCVVSSLGITERGKKSVKLS
LNPKNVNRVLSAEALKPGMLLTGTVSSLEDHGYLVDIGVDGTRAFLPLLKAQEYIRQKNK
GAKLKVGQYLNCIIEEMKGNGGVVHLSIGHSEVSTALATEEQSWTLNNLLPGLVVKAQVQ
KVTPFGLTLNFLTFFTGVVDFMHLDPKKAGTYFSNQAVKACILCVHPRTRVVRLSLRPIF
LQPGRPLSRLSCQHLGAVLNDVPVQGFFKKAGATFRLKDGVLAYARL------SHLSDSK
NVFNPEAFKPGNTHKCRIIDYSQMDELALLSLRTSIIEAQYLRYHDI
PF00575 // ENSGT00390000012228_0_Domain_1 (468, 538)
KPGAVVKGTVLTI
KPYGMLVKVGEQMRGLVPPMHLADILMKNPEKKYHIGDEVKCRVLLCDPEAKKLMMTLKK
TLVESKLPAITCYADAKPGLQTHGFIIRVKDYGCIVKFYSDVQGLVPKHELST-EYIPDP
ERVFYTGQVVKVAVLNSEPPKERMLLSFKLLRDTEPKKE--PAGHNQKKGKAINVGQLVD
VKVLEKTKDGLEVAVLPH--NTRAFLPTSHLSDHVTNGPLLHHWLQAGDTLHRVL---CL
SQSEGHVLLCRKPALVSAVEGGQDPKNFSEIHPGM
PF00575 // ENSGT00390000012228_0_Domain_4 (756, 823)
LLVGFVKSIKDYGVFIQFPSGLSGL
APKAIMSDKFVTSTSDHFVEGQTVVAKVTNVDEEKQRMLLSL
ENSGT00390000012228_0_Linker_4_5 (823, 1077)
RLSDCGLGDLATTSLLLL
SQCLEELQGVRSLMS--NR-DSVLIQTLAEMTPGMFLDLVVQEVLEDGSVVFSGGPVPDL
-VLRASRYHRGGQEVESGQKKKVVILNVDLLKLEVHVSLHQDLVNRK-AKKLRKGSEHQA
IVQYLEKSFAIASLVK--TGHLVAFSLTSHLNDTFRFDSEKLQVGQGVSLTLKTTEPGVT
GLLLAVEGPAAKRTMRPPRKDSETVDEDE-----------EVDPALTVGTIKKHTL
PF00575 // ENSGT00390000012228_0_Domain_5 (1077, 1139)
SIGD
MVTGTVKSIKPTHVVVTLKDGIIGCIHASHILDDVPEGTSPTTKLKVGKTVTARVIGGRD
MKTFKFLPISHPRFVRTVPELSVRPSELE------DGHTALNTHSVSPMEKIKHYQAGQT
VTCFLKKYNVVKKWLEVEIAPDIRGRIPLLLTSLSFKVLKHPDK-KFRVGQA-LRATIVG
PD-SSKAFLRLSL-IGPHKLEKGEVAIGRVVKVTPNEGLTVSFPFGKIGTVSLFHISDSY
SETPLEDFVPQKVVRCYILSTEDNVLTLS---LRSSRTNPGTKSKVEDPEINSIQDIKEG
QLLRGYVRSIQ-PHGVFFGLGPSVVGLARYPHVSQLSPSKKALYNKHLPEGKLLTARVLR
----------------LNHQKNLVELSFLPRDTGEPDVLSASLEVPLSEQEERKTEAEEK
DQKGEKKNQKRN-----E---KNQKWLEE--VELPSK---------EKQQPQKPQAQ--K
RGRQEHQEPG------SEQERVSKKPKKAGPSEED----DSLLDVYYREGEEE-GEETNM
------------------------------LSKEKQTKPAEAPRLQLSSGFAWNVGLDSL
TP-ALPPLAESSDSEEDE-KPHQATK--KKSKKERELEKQKAEKELSRIEEALMDPGRQP
ESADDFDRLVLSSPNSSILWLQYMAFHLQATEIEKARAVAERALKTISFRE-EQEKLNVW
VALLNLENMYGSQESLTKVFERAVQYNEPLKVFLHLADIYTKSEKFQEASELYNRMLKRF
RQEKAVWIKYGAYLLRRSQAGASHCVLQRALECLPSKEHV
PF05843 // ENSGT00390000012228_0_Domain_7 (1901, 2008)
DVIAKFAQLEFQLGDPERAK
AIFENTLTTYPKRTDVWSVYIDMTIKHGSQKDV-RDIFERVIHLSLAPKKMKFFFKRYLD
YEKQHGTEKDVQAVKAKALEYVEARSSVED---
ENSRNOP00000027512 (view gene)
-MANLEESFPRGGTRK--PHKSEKSSQPVVEQDNLFDIS---TEEGSVKRK-KSQKGPAK
T----KKLKIEKRKSNKSMKEKFEILSLESLCEGMRILGCVKEVNELELVVSLPNGLQGF
VQVTEICDAYTQKLNEQVAQEEPLEDLLRLPELFSPGMLVRCVVSSLDVTESGKKSVKLS
VNPKRVNKVLSAEALRPGMLLTGTVSSLEDHGYLVDIGVDGTRAFLSLQKAQEYIRQKNK
GAKFKVGQYLTCVVEELKSNGGVVSLSVEHSQVSSAFATEEQSWNLNNLLPGLVVRAQVQ
KVTQFGLQLNFLTFFTGLVDFMHLEPKKMGSYSSKQTVKACILCVHPRTRVVRLSLRPIF
LHPGRPLTRISYQQLGTVLDDASVEGFFEKAGAIFRLRDGVLAYARL------SHLSDSK
KAFSAEAFKLGSTHRCRIIDYSQMDELALLSLRKSIIAAPFLRYQDIKTGTIVKGKVLAL
KPFGMLVKVGEQMRGLVPSMHLADIMMKNPEKKFNTGDEVKCRVLLCDPEAKKLIMTLKK
TLVTSKLPAITCYEDAKPGLQT
PF00575 // ENSGT00390000012228_0_Domain_3 (563, 628)
HGVIIRVKDYGCLVKFYNDVQGLVPKHELSA-QHIPDP
ERVFYTGQVVKVAVLNCEPSKERMLLS
ENSGT00390000012228_0_Linker_3_4 (628, 754)
FKLLSGSEPKDE--SVKNSKKKGSTVNTGQLVD
VKVLEKTKNGLEVAILPH--NIPAFLPTPHLSDHVANGPLLHHWLQTGDTLHRVL---CL
SQSEKHILLCRKPALVSTVEGGQDPKSLSEIQP
PF00575 // ENSGT00390000012228_0_Domain_4 (754, 823)
GMLLIGFVKSIKDYGVFVQFPSGLSGL
SPKTIMSDKFVTTPSEHFVEGQTVVAKVTNVDESKQRMLLSL
ENSGT00390000012228_0_Linker_4_5 (823, 1077)
RLSDCSLGDSASTSFLLL
CQCLEELQGIRSLMS--NQ-DSVLIQTLADMTPGMVLDAMVQEVLENGSVVFGGGPVPDL
-ILRASRYHRAGQELEPGQKKKVVVLHVDALKLEVHVSLHQDLVNRK-ARKLRKNSRHQG
IVQHLEESFAVASLVE--TGHLVAFSLISHLNDTFHFDSEKLRVGQGVCLTLKTTEPGVT
GLILAVEGPASKRIRMPAQRDSETVDDKGEEEE------EEEEEDLTVRSKKSHSL
PF00575 // ENSGT00390000012228_0_Domain_5 (1077, 1142)
AIGD
KVTGTIKSVKATHAVVTLDDGFIGCIHVSRILDDVPEGVSPTTTLKAGKKVTARVIGGRD
VKTSKFLPISHPRFVLTILELSVRPSELK-----G-DYRALNTHSVSPMEKIRQYQAGQT
VTCFLKKYNVMKKWLEVDIEPDIRGRIPLLLTSLSFKVLKHPDK-KFQIGQA-IKATVVG
PD-IPRAFLCLSL-IGPYKLEEGDVAMGRVLKVLPNKGLTVSFPFGRIGKVSVFHLSDSY
SEEPLTDFCPQKIVRCYILSTAHRMLALS---LRSSRTNKETKSKIEDPEVNSIEDIQAG
QLLRGYVKSIL-PSSVVIGLGPSVMGLVKHSHVSQCVSREKELYDKCLPEGKLVTARVLC
----------------VNPKKNLIELSLLPSDTGKPDVFSASPEPPLPKQEGREGGTEK-
GLKGE--SKRSQR---R--REKNQKMRE--ESGLYSQ---------EKKEPRKSQRG--G
QSKRERQESE------SEQELVNKRPKKSGAPEDD----DSGVEVYYREGEDE-VEEPKV
------------------------------PPGGKQSKPTEVPRLQLSKGFIWDVGLDSL
TP-ALPLRGESSDSEEDE-QPHQAKK--KKGKKERELEKQKAEKELSRIEEALMDPGRQP
ESADDFDRLVLSSPNSSILWLQYMAFHLQATEIEKARAVAERALKTISFRE-EQEKLNVW
VALLNLENMYGSQESLAKVFERAVQYNEPLKVFLHLADIYTKSEKFKEAGELYNRMLKRF
RQEKAVWIKYGAFVLGRSQAGASHRVLQRALECLPT
PF05843 // ENSGT00390000012228_0_Domain_7 (1897, 2006)
KEHVDVIVKFAQLEFQLGDVERAK
AIFENTLTTYPKRTDVWSVYIDMTIKHGSQKEV-RDIFERVIHLSLAPKRMKFFFKRYLD
YEKQHGTEKDVQAVKAKALEYVEAKSSALEDQ-
ENSMGAP00000010918 (view gene)
-MASMEENFPRGGIQKKPTETTGKKAKPKFEQDNLFDIH---HEEQTQKRK-RSEGDHRK
Q----KKFKADKKAPAKDIA--IEPLTIQEICEGMLLLGCIKEVTFFELVISLPNGLTGF
VPVTQISDAYSELLNEQVTQGELLEDLNSLSDLYSPGMLVRCVVTSVEKSADGRRSIKLS
INPKNVNKGLNASALTSGMLLSGFVRSVEDHGYLIDIGVRGTHAFLPHQKAQNYIKAVKR
GSDLKIGQSLNCLIEEVKNEGRVVRLSADRSEVAASIATEQQNWTLSNLLPGLVVKAQVQ
KVAPLGISLTFLSSFTGIVDFMHVDPEKSTNYSPNQVVKACILSTHPTSKVVHLTLRQAF
LCPGGSPNQLSNDRIGAVVEESTVKAFYKQFGAVFELDDGMLAFARL------KHLSKTR
KSFKPAAFKAGCKHKCRIIDYSLMDEMCIVSLKHQIIEARFLRYQDIHTGDVMQGKVLSL
KPIGMQVKVTDGIKGLVPSMHLADVILKQPEKKYNVGDEVRCRVLECNPEEKKLFLTLKK
TLVQSKLPVLSSYE
PF00575 // ENSGT00390000012228_0_Domain_3 (555, 629)
DAEPGLITHGFVVCAREFGCIVKFYNDVKGLVPKNELSS-EPISCP
DKVFHDGQVVKVMVLKCEPQQERLLLSF
ENSGT00390000012228_0_Linker_3_4 (629, 750)
RLSSKPVPEGRTEC-TPKKKQQVKYQIGEMVD
VKVLKKNENGLEVSILEDGDDVIAWLPTGHLSDFVANSKLLWHCLQEGDVLPRVM---CL
SDKGDRIILCRKSAVISAVQEEQVVRSFS
PF00575 // ENSGT00390000012228_0_Domain_4 (750, 823)
EIQPGVLLTGYVRKVMPFGVFVEFPFGVTGL
APKVSMSDKFVTDTKDHFVVGQTVIAKVMSIDEEKQRVLLNL
ENSGT00390000012228_0_Linker_4_5 (823, 1075)
KVSECSSGDSAAESFSLL
NQYFKEMEEIKNLLR--RR-ESGLAQCLSELVPGKELQLVVQDVMEDGSALFSGSCVRGW
-TVTATHYHLGGKKVVPGEKAKGLVLHVDAITSKVYVSLREELLKKE-PSKLTKNSQHPA
IVQHIAEEFAIVSLLD--SGRLAAVPIASHFNDTFRFDSEKMKVGQRIYATLKTVKANDL
GVVLAVQDPTKKNAFVRDRKESETALE------------------ETLAAAVKH
PF00575 // ENSGT00390000012228_0_Domain_5 (1075, 1145)
SLSLGD
IVTGTVKSVKPTHVTVAIDDKLTGSIHASQILDEVPIYSFPTYTLKAGQKVTARVIGGRD
VNTHRYLPITHPHFTRSVPELSIRPSEIE-----GKVETM--RDDT--CEKLGPYNVGQT
VTCFVRKYNILKNWLEVEVAPDVRGRVPRLLLSLNTKVLKHPEK-NFKNGQA-LSATVTG
TDATET-NLFLSL-TGIQSLEPGTITVGMVAKMIPHIGLTITLPGGKTGKVSIFHLSDKY
TESPLSDFKIGKVVRCYILSNENGKIQLS---LRQSRLNPKNSSKVEDAEITSIKDVKKG
QLLRGYVKSVT-PSGVFFGLSASLLGRILFQNVSPYFVQKHSLYEKYLPEGKLLTAKVLD
----------------VNKNENHVELSLLPEDTEMPSVLPESLGLPRYGAEEEKREEDKE
EKKEK-----VKMKRKQ--RRVNSESEQLEICKDEKQILL--GWSLLN-KQPICLRSPCA
HFP-----LLQE----AK-----PKKRKLSPSDEN----DSGIEVYYREEEDGDQEGEAA
E-----------------------------KKSRQIRKCGEVSRLQVSTGFTWDEDINAV
EVPVLNQKEESSESEEEEENLQSKK---KQTKKEKELEKQKKEKELCKLEAALMDPSRQP
QSADDFDRLVLSSPNSSILWLQYMAFHLQATEIEKARAVAERALKTICFRE-EQEKLNVW
VALLNLENMYGTEETLMKVFERAVQYNEPLKVFQHLCDIYASSEKYKQAEELYHTMLRRF
RQEKSVWLKYASFLLKQGQTEATHRLLERALKALPTKEHVDVISRFAQLEFRFGDPEHAK
ALFESTLNSYPKRTDIWSIYMDIMIKQGSQKEV-RDIFERVIHLNLAPKKMKFFFKRYLD
YEKKYGTTETVMAVKTAALEYVEAKSSLADT--
ENSPPYP00000003050 (view gene)
-MANLEESFPRGGTRK--IHKPEKAFQQSVEQDNLFDIS---TEEGSTKRK-KNQKGPAK
T----KKLKIEKRESSKSAREKFEILSVESLCEGMRILGCVKEVNELELVISLPNGLQGF
VQVTEICDAYTKKLNEQVTQEQPLKDLLHLPELFSPGMLVRCVVSSLGITDRGKKSVKLS
LNPKNVNRVLSAEAL
PF00575 // ENSGT00390000012228_0_Domain_0 (196, 268)
KPGMLLTGTISSLEDHGYLVDIGVDGTRAFLPLLKAQEYIRQKNK
GAKLKVGQYLNCIVEKVKGNGGVVSLSIGHSEVSTAIATEEQSWNLNNLLPGLVVKAQVQ
KVTPFGLTLNFLTFFTGVVDFMHLDPKKAGTYFSNQAVRACILCVHPRTRVVRLSLRPIF
LQPGRPLTRLSCQKLGAVLDDIPVQGFFKKAGATFRLKDGVLAYARL------SHLSDSK
NVFNPEAFKPGNTHKCRII-----------------------------------------
-------------------------------------------VLLCDPEA-KLMMTLKK
TLIESKLPVITCYADAKPGLQ
PF00575 // ENSGT00390000012228_0_Domain_3 (562, 628)
IHGFIIRVKDYGCIVKFYNNVQGLVPKHELST-EYIPDP
ERVFYTGQVVKVVVLNCEPSKERMLLS
ENSGT00390000012228_0_Linker_3_4 (628, 752)
FKLSSDPEPKKE--PAGHSQKKGKAINVGQLVD
VKVLEKTKDGLEVAVLPH--NIRAFLPTSHLSDHVANGPLLHHWLQAGDILHRVL---CL
SQSEGHVLLCRKPALVSTVEGGQDPKNFSEI
PF00575 // ENSGT00390000012228_0_Domain_4 (752, 823)
HPGMLLTGFVKSIKDYGVFIQFPSGLSGL
APKAIMSDKFVTSTSDHFVEGQTVVAKVTNVDEEKQRMLLSL
ENSGT00390000012228_0_Linker_4_5 (823, 1078)
RLSDCGLGDLATTSLLLL
SQCLEELQGVRSLMS--NR-DSVLIQTLAEMTPGMFLDLVVQEVLEDGSVVFSGGPVPDL
-VLRASRYHRAGQEVESGQKKKVVILNVDLLKLEVHVSLHQDLVNRK-AKKLRKGSEHQA
IVQHLEKSFAIASLVE--TGHLAAFSLTSHLNDTFRFDSEKLQVGQGVSLTLKTTEPGVT
GLLLAVEGPAAKRTMRPTRKDSETVDEDE-----------EVDPALTVGTIKKHTLS
PF00575 // ENSGT00390000012228_0_Domain_5 (1078, 1138)
IGD
MVTGTVKSIKPTHVVVTLEDGIIGCIHASHILDDVPEGTSPTTKLKVGKMVTARVIGGRD
MKTFKYLPISHPRFVRTIPELSVRPSELE------DGHTALNTHSVSPVEKIKQYQAGQT
VTCFLKKYNVVKKWLEVEIAPDIRGRIPLLLTSLSFKVLKHPDK-KFRVGQA-LRATVVG
PD-SSKAFLCLSL-IGPHKLEEGEVAMGRVVKVTPNEGLTVSFPFGKIGTVSIFHMSDSY
SEMPLEDFVPQKVVRCYILSTADNVLTLS---LRSSRTNPETKSKVEDPEINSIQDIKEG
QLLRGYIGSIQ-PHGVFFRLGPSVVGLARYSHVSQHSLSKKALYNKHLPEGKLLTARVLR
----------------LNHQKNLVELSFLPGDTGKPDVLSASLEGPLPKQEERKTEAGER
DQKAEKKNQKRN-----E-K-KNQKGQEE--VDLPSK---------EKQQPQKPQAQ--K
RGGRERRESG------SEQERVSKKPKKAGLSEED----DSLVDVYYREGKEE-AEETNV
------------------------------LPKEKQTKPAEAPRLQLSSGFAWNARLDSL
TP-ALPPLAESSDSEEDE-KPHQATK--KKSKKERELEKQKAEKELSRIEEALMDPGRQP
ESADDFDRLVLSSPNSSILWLQYMAFHLQAMEIEKARAVAERALKTISFRE-EQEKLNVW
VALLNLENMYGSQESLTKVFERAVQYNEPLKVFLHLADIYAKSEKFQEAGELYNRMLKRF
RQEKA
PF05843 // ENSGT00390000012228_0_Domain_7 (1866, 2008)
VWIKYGAFLLRRSQAAASHRVLQRALECLPSKEHVDVIAKFAQLEFQLGDAERAK
AIFENTLSTYPKRTDVWSVYIDMTIKHGSQKDV-RDIFERVIHLSLAPKRMKFFFKRYLD
YEKQHGTEKDVQAVKAKALEYVEAKSSVLED--
ENSTSYP00000028931 (view gene)
---------------------------------------------ESSKR-KKSQKGPAK
T----KKLKTRKRESSKSVREKFEILSVESLCEGMRILGCVKEVNELELVVSLPNGLQGF
VQVTEICDAHTERLKEQLAQEEPLKDLLHLPELFSPGMLVRCVVSSLGVTERGRSSVQLS
LNPRSVNRVLSAEVL
PF00575 // ENSGT00390000012228_0_Domain_0 (196, 268)
KPGMLLTGTVSSLEDHGYLVDIGVDGTRAFLPLPKAQESAHPRNK
GAKLKVGQYLHCVIEEVRGGGGVVTLSVRPSELSAAIATEEQSWTLHNLLPGLVVRAQVQ
KVTPFGLTLSFLTFFTGVVDFMHLDPKKAGMYFSQQAVRACLLCVHPRTRAVRLSLRPIF
LQPGRPLPQLSHQHLGAVMDDVPVQGFFNRAGATFQLKDGTLAYARL------SHLSDSK
SVFNPESFRPGNTHKCRVIDYSQMDGLALLSLRTSVIEAQFLRYHDIKPGAVVKGTVLTV
KPFGMLVKVGEHMRGLVPTLHLADVLMKNPEKKYPVGAEVQCRVLLCDPEVKKLMMTLKK
TLVESRLPAVTCYADARPGLQTH
PF00575 // ENSGT00390000012228_0_Domain_3 (564, 628)
GFIAKVADYGCIVKFYSDVRGLVPRQELGA-QCIPHP
ERVFYAGQVVKVAVLSCEPAKERMLLS
ENSGT00390000012228_0_Linker_3_4 (628, 754)
FKLMSPPEAPLE--LAGHSRKKRRAMSVGRLVD
VKVLEKTTEGLEVAILPH--NVPGFLPTPHLSDHVANGPLLHHWLQAGDTLHRVL---CL
GQSEGRALLCRKPALVSAVAGGQDPGAFSEIRP
PF00575 // ENSGT00390000012228_0_Domain_4 (754, 823)
GMLLLGFVRSIRDYGVFVQFPSGLSGL
APKAIVSDKFVTSPSDHFVEGQTVVAKVTSVDAERQRVLLSL
ENSGT00390000012228_0_Linker_4_5 (823, 1078)
RLSDCALGPAAPTSLLLL
SQCLDERQGVRSLMG--AR-DSVLVQTLAQMTPGMVLELVVQEVLEDGSVVFSGGPVPDL
-VLRASRYHRAGRELESGQKRKVVVLNVDMLKLEVHVSLHQDMVKRK-ARKLKKGSEHRA
TVQHLEESFAIASLVE--TGHLVAFSLASHLNDTFRFDSEKLQVGQGVSLSLKTTDPGVT
GLLLAVEGPVAKRTMSQAQKDSETVDEEE-----------DVDPALAVGTTKKHALS
PF00575 // ENSGT00390000012228_0_Domain_5 (1078, 1142)
IGD
VVTGTVKSVKPTHVVVTLAGGAVGCIHASHILDDVPEGATPTATLKVGRTVTACVIGGRD
VKTSKFLPVSHPGFVRTVLELSVRSSELQ------AGCTALDTHCASPVEKAREYQAGQT
VTCFLRKYNVVKKWLEVELGPDVRGRIPLLLTSLSFKVLKHPDK-KFRAGQA-LRATVVS
PD-SGKAFLCLSL-IGPHRLEEGEVAMGRVAKVTPNEGLTVAFPFGRTGRVSVFHVSDSY
SEAPLQGFVPQKVVRCCVLSAADEELILS---LRPSRTNPETKSKVEDPEVNSVEDVRAG
QLLRGYVQSVQ-PHGVLLGLGPAVVGVARFRHVSQRSLSRRALYSKYLPEGKLLSARVLR
W--------------VLDPRKKLVELSFLPSDTGRPDVLPASLGLEDE-----KAEAEER
PQPGEEAQRQHRE---RSG--EDPEGT-------------------------------GE
PRKRAHQEQGG-----VRAAGSGKRLKRAGPWED-----DRGTDVYYREGEDT-GGV--A
------------------------------GPQETPSRPVAVPCLQLSSGFAWDAGLDSL
AP-ALPPGGESSDSEEDTEPP-QATQ--KKSRKERALERQQAEKELSRVEAALMDPARQP
ESADDFDRLVLSSPDSSILWLQYMAFHLQATEIEKARAVAERALKTISFRE-EQEKLNVW
VALLNLENMFGSPGSLARVFERAVQHSQPLKVFLQLAAIYSKSEKFQEAGELYNRMLKRF
RQEKT
PF05843 // ENSGT00390000012228_0_Domain_7 (1866, 2004)
VWIQYGAFLLRRSQADASHRVLQRALACLPSKEHVDVIAKFAQLEFQLGDAERAK
AMFESTLNTYPKRTDVWSVYIDMAIKHGSQKDV-RDLFERVIHLSLAPKRMKFFFKRYLD
YVKQHGTERDVQAVKAKALEYVEARSAMLED--
ENSFALP00000009154 (view gene)
-MASMEENFPRGGIQKKPAE--GKTPKPKLERDNLFDVQ---HEEKSQKRK-RSQKDQGK
QQESKKRFKADKEAAAKDNVMIIGPLTIEALSEEMLLLGCIKEVTDYELAISLPNGLSGF
VPVTQISDAYSKLLTKQVAQGELLEELNSLPDLFSPGTLVRCIVTSIEKSDDGRRSVKLS
IDPKKVNKGLNSTALAAGMLLSGSVMSVEDHGYLIDIGVTGTHAFLPHQKAKTYIKALKK
GPDLKIGQNLNCLIVEVKNEGRVVCLSIDRSEVAASIATERQNWTLSNLLPGLVVKARVQ
KLAPLGMKLTFLSYFTGIVDFMHMDPEKSMSYSADQVVRACVLSVHPTSRAVRLSLLPPF
LHAGGAPRQLPGQRLGAVLEEATVKAFYKQFGAVFELDDGTLAFARL------KHLSKTR
KSFKPGAFKEGCKHKCRIIDYSLMDEMCIVSLKHQIIEARFLQYQDIHVGDVVQGKVVSL
KPIGMQVKVADGIRGLVPSIHLSDVILKQPEKKYNIGDEVKCRVLECNPEGKKLILTLKK
SLVQSKLPVLSNYEDAK
PF00575 // ENSGT00390000012228_0_Domain_3 (558, 628)
PGLITHGFVVCAREFGCIVKFYNDVKGLVPKNELSS-EPISCP
DKVFYEGQVLKVMVLKCEPQQERLLLS
ENSGT00390000012228_0_Linker_3_4 (628, 752)
FKLSSKPGPEDKWKC-TPKEKQEVKYQIGEMVD
VKILKKKDNGLEVSILEDEDNVVAWIPMLHLSDFVATSKLLWHCLQEGDVLPRVM---YL
SDKGEHIILSRKSAVISAVQEQQVVRSFSEI
PF00575 // ENSGT00390000012228_0_Domain_4 (752, 823)
QPGMLLTGYVRNVMPFGVFVEFPFGVTGL
APKVSMSDKFVTDTKDHFVVGQTVIAKVMSIDEEKQRVLLNL
ENSGT00390000012228_0_Linker_4_5 (823, 1078)
KVSECSSGDSAAESFALL
NQYFEELKGIKDLLK--RGE-----PSICELVPGKRVHLVVQGVREDGSALFSGCSATGW
-TVTATHYHLGGKNIAHGEKRKALVLHVDALKSEVYVSLREELLKQRP-RQLRENSQHSA
VVQHITEHFAIVSLGQ--TAQLAAVPIACHFNDTFRFDSEKLSVGRTISVTLKAVKKNHH
GVLLAVQGPAKRNVFVRVRNESETALE------------------EMLP-ALKHSLS
PF00575 // ENSGT00390000012228_0_Domain_5 (1078, 1139)
TGN
LVTGTVKSVKPTHVTVAIDDKLTGSIHASRILDEVPIGSFPTSTLKTGQKVTARVIGGRD
VNTHRCLPITHPHFKQSIPELSIRPSEKE-----GEFTAM--LNLKEETSLKELYSVGQT
VTCFVKKYNMLKNWLEVEVGPDIRGRVPHLLLSLNTKVLKHPEK-TFKNGQA-ISATVTG
TDATGT-NLCLSL-TGIQSLEQGTISVGMVIKVTPHTGLTIALPGGKTGKVSIFHLNDTY
SEDPLVNFKVGKIVRCYILSNENGKIQLS---LRQSRLNPKINSKVEDIEITSIKDVKKG
QLVRGYVKSIT-PSGVFFGLSASLLGRILFQNVSPYFVQKHSLYEKYLPEGKLLTAKVVG
----------------VNRKEKHIELSLLPEDTGMPSVLPESLGLPQYGAEEEKREADIE
EKREE-----PKLKKKR--RGNIE------------------------------------
--------NHQE----AK-----PKKRKICPADEN----DSGIEVYYREEEEDDQEEEAD
K------------------------------KKTKVKKPGEAPRLQVSMGFTWDED-NAM
DIPVLDQKEESSESEEEEEDMQSKLK--KRTKKEKELEKQKEEKELCKVEAALMDPSRQP
QSADDFDRLVLGSPNSSILWLQYMAFHLQATEIEKARAVAERALKTISFRE-EQEKLNVW
VALLNLENMYGTEETLMKVFERAVQYNEPLKVFQHLCDIYASSEKYKQAEELYQTMLKRF
RQEKSVWLKYASFLLKQGQAEATHRLLERALKALPTKEHVDVISR
PF05843 // ENSGT00390000012228_0_Domain_7 (1906, 2009)
FAQLEFHSGDTEHAK
ALFESTLSSYPKRTDVWSIYMDIMIKHGSQKEV-RDIFERVIHLSLAPKKMKFFFKRYLD
YEKKFGTAESVLAVKRAALEYVETKSSLADT--
ENSPTRP00000005127 (view gene)
-MANLEESFPRGGTRK--IHKPEKAFQQSVEQDNLFDIS---TEEGSTKRK-KSQKGPAK
T----KKLKIEKRESSKSAREKFEILSVESLCEGMRILGCVKEVNELELVISLPNGLQGF
VQVTEICDAYTKKLNEQVTQEQPLKDLLHLPELFSPGMLVRCVVSSLGITDRGKKSVKLS
LNPKNVNRVLSAEALKPGMLLTGTVSSLEDHGYLVDIGVDGTRAFLPLLKAQEYIRQKNK
GAKLKVGQYLNCIVEKVKGNGGVVSLSVGHSEVSTAIATEQQSWNLNNLLPGLVVKAQVQ
KVTPFGLTLNFLTFFTGVVDFMHLDPKKAGTYFSNQAVRACILCVHPRTRVVRLSLRPIF
LQPGRPLTRLSCQNLGAVLDDVPVQGFFKKAGATFRLKDGVLAYARL------SHLSDSK
NVFNPEAFKPGNTHKCRIIDYSQMDELALLSLRTSIIEAQYLRYHDI
PF00575 // ENSGT00390000012228_0_Domain_1 (468, 538)
EPGAVVKGTVLTI
KSYGMLVKVGEQMRGLVPPMHLADILMKNPEKKYHIGDEVKCRVLLCDPEAKKLMMTLKK
TLIESKLPVINCYADAKPGLQTHGFIIRVKDYGCIVKFYNNVQGLVPKHELST-EYIPDP
ERVFYTGQVVKVVVLNCEPSKERMLLSFKLSSDPEPKKE--PAGHSQKKGKAINTGQLVD
VKVLEKTKDGLEVAVLPH--NIRAFLPTSHLSDHVANGPLLHHWLQAGDILHRVL---CL
SQSEGRVLLCRKPALVSTVEGGQDPKNFSEIHPGMLLI
PF00575 // ENSGT00390000012228_0_Domain_4 (759, 823)
GFVKSIKDYGVFIQFPSGLSGL
APKAIMSDKFVTSTSDHFVEGQTVAAKVTNVDEEKQRMLLSL
ENSGT00390000012228_0_Linker_4_5 (823, 1077)
RLSDCGLGDLAITSLLLL
NQCLEELQGVRSLMS--NR-DSVLIQTLAEMTPGMFLDLVVREVLEDGSVVFSGGPVPDL
-VLKASRYHRAGQEVESGQKKKVVILNVDLLKLEVHVSLHQDLVNRK-ARKLRKGSEHQA
VVQHLEKSFAIASLVE--TGHLAAFSLTSHLNDTFRFDSEKLQVGQGVSLTLKTTEPGVT
GLLLAVEGPAAKRTMRPTRKDSETVDEDE-----------EVDPALTVGTIKKHTL
PF00575 // ENSGT00390000012228_0_Domain_5 (1077, 1139)
SIGD
MVTGTVKSIKPTHVVVTLEDGIIGCIHASHILDDVPEGTSPTTKLKVGKTVTARVIGGRD
MKTFKYLPISHPRFVRTIPELSVRPSELE------DGHTALNTHSVSPVEKIKQYQAGQT
VTCFLKKYNVVKKWLEVEIAPDIRGRIPLLLTSLSFKVLKHPDK-KFRVGQA-LRATVVG
PD-SSKTFLCLSL-TGPHKLEEGEVAMGRVVKVTPNEGLTVSFPFGKIGTVSIFHMSDSY
SETPLEDFVPQKVVRCYILSTADNVLTLS---LRSSRTNPETKSKVEDPEINSIQDIKEG
QLLRGYVGSIQ-PHGVFFRLGPSVVGLARYSHVSQHSPSKKTLYNKHLPEGKLLTARVLR
----------------LNHQKNLVELSFLPGDTGKPDVLSASLEGQLTKQEERKTEAEKR
DQKGEKKNQKRN-----E-K-KNQKGQEE--VEMPSK---------EEQQPQKPQAQ--K
RGGQECRESG------SEQERVSKKPKKAGLSEED----DSLVDVYYREGKEE-AEETNV
------------------------------LPKEKQTKPAEAPRLQLSSGFAWNVGLDSL
TP-ALPPLAESSDSEEDE-KPHQATI--KKSKKERELEKQKAEKELSRIEEALMDPGWQP
ESADDFDRLVLSSPNSSILWLQYMAFHLQATEIEKARAVAERALKTISFRE-EQEKLNVW
VALLNLENMYGSQESLTKVFERAVQYNEPLKVFLHLADIYAKSEKFQEAGELYNRMLKRF
RQEKA
PF05843 // ENSGT00390000012228_0_Domain_7 (1866, 2008)
VWIKYGAFLLRRSQAAASHRVLQRALECLPSKEHVDVIAKFAQLEFQLGDAERAK
AIFENTLSTYPKRTDVWSVYIDMTIKHGSQKDV-RDIFERVIHLSLAPKRMKFFFKRYLD
YEKQHGTEKDVQAVKAKALEYVEAKSSVLED--
ENSMODP00000013871 (view gene)
-MASQEDSFPRGGSKKKAHPV--KAPQQPIEHDNLFDIP---TEEGSRKRK-RNPEQAAK
N----KRSKTEKKEPSKSEAEQSGILSIEVLSEGMRLLGCVKEVNNLELVISLPNDLWGY
VQATNICDAYTKKLNEQVDREEPLEDLAPLSKLFQPGMLVRCAVSSLKSTSKKNKSIKLS
LNPKDVNGVLSPAAL
PF00575 // ENSGT00390000012228_0_Domain_0 (196, 268)
KPGMLLTGTVDSVEDHGYLVDIGVGGTKAFLPWQKEQEYVKQKNK
GTKLQVGQYLNCLIEEVKGNGGSVRLS
ENSGT00390000012228_0_Linker_0_1 (268, 468)
TIQSEVSAAIATEEQNWTLDNLLPGLVVKAQVQ
KVTPYGLSLSFLSSFTGLVDFMHLDSKKTGHYFQTQMVRACILSVHPRTKSVRLTLHSSF
LQAGRPITRLCHHLIGAVLNDVPVQSFYTKAGATFRLKDGSLAYARI------RHLSQTE
KSFKPEKFKPGNLHRCRVIDFSPMDDLALLSLKTSIIEAPFLRYHDI
PF00575 // ENSGT00390000012228_0_Domain_1 (468, 539)
QPGQIVKGKVFTL
RSYGMIVKVTEQIKGLVPTLHLADVQIRNPQKKYRVQDEVKCRVLMCDPENKKLLMTLKK
TLVESSLPALTNYKEAKPDLQTHGFISSIKDCGCIVKFYNDVRGLVPQRELGA-QPISAP
EEVFYVGQVVKVTVLKSEPEQERMLLSFRLFTRNFIGKGRE--------SWVRVLKGLVD
VKVKKKTEKGLEVSILPD--DISALLPTTHLSDNVTNSQLLCYWLQAGDILHKVL---CL
SHSDGHIVLCRKPALISAVESGQDPKVFSE
PF00575 // ENSGT00390000012228_0_Domain_4 (751, 823)
FQPGMLLTGFVKSIKAYGIFVQFPSGLSGL
APKSALSDKFVTTISDHFVEGQTVVAKVTNVDEEKQRMLLSL
ENSGT00390000012228_0_Linker_4_5 (823, 1077)
RLSDVSQEDTTASSLTLL
SQCLEELQGVRSLMS--SRD-SVLTQTLAEMTPGLLVDLVVQDMSSDGSLVFSNGSVPGL
-VLRASKYHQGGKAVDPGQRTKAVILHVDTQKSEVHVSLRQELVNRK-VKQLKKDTEHRA
VIEHLEKTFAIASLVE--TGQLIAFPVASHLNDTFRFDSEKLQVGQGVSVIIKSTKPCDI
GLFLAVESSVKKRTPALPSVAPESAGQD---------------PGVVSELLEKPTL
PF00575 // ENSGT00390000012228_0_Domain_5 (1077, 1137)
PIGE
MVTGTVKSIKATHVIVTLENGLTGYIHASQILDDVSHGTHPTTTLKVGNPVTARVIGQRT
WLTHKSLPISHPSSTQTVSELSIRP-----SELEKNISSDPSTQSSSPTEKLKQYFPGQT
VVCFMRKFNVIKKWLEVEITSDIRGRIPQLLTSLSFKVYLNFYVPRYRTSSYCLNMTL-F
PSVWNTLLYHLEF-FSS---------LVQIKQSSLGAGIQIVCPIDRP-RVSLSHRK---
-----NGTK----------SSLELSLSLSLPLSLSFRTNPKMKSKIEDPEVTSMKDIKEG
QLLRGYVEAIK-KQGIFFRISPTLVGRVKYQHVTTYLPFDRALYQTYLPEGKLLSAKVLR
----------------VNRKQNLLYLSFLPKDTGKPDVFPESLGLPPRDQEREL----LS
NQPK------KKRKLEQ--EEEDHAKQKQEDQSQPHREPGAKQKQELQTPSVRPGEKAEN
KGKRKVPEVERE----Q--EIVSKKKKQSHPLEED----DSGVEVNYKEEKEKRFKQSKV
R-------------------------------KKKQTKPTEVPRLQLSSGFAWDVSLDTL
AP-AMPPREDSSDSEDEEA-SQATLK---KSKKGKELEKQEAEKELSRIEAALMDPNWKP
ETADDFDRLVLSSPNSSILWLQYMAFHLHATEIEKARAVAERALKSISFRE-EQEKLNVW
VALMNLENMYGSKETLTKVFERAVQYCEPLKVYFQLADIYTKSEKYQAAEELYSRMLKRF
RQEKTVWIRYGAFLLQRGQADANHRLLQRSFNCLPQKEHVDVIS
PF05843 // ENSGT00390000012228_0_Domain_7 (1905, 2004)
KFAQLEFQLGDAERAK
AMFETTLSSYPKRTDVWSVYIDMIIKYGSQKEA-RDIFERVVHLSLAPKRMKFFFKRYLD
YEKQHGTAETVQAVKEKALAYVEATGTLAES--
ENSPCOP00000022464 (view gene)
-MASLEESFPRGGTRK--IHKSEKAFQQSVEQDNLFNIS---TEEESTKRK-KNQKGPAK
T----KKLKIEKRESSKSVREKFEILSVESLCEGMRILGCVKEVNELELVISLPNGLRGF
VQVTEICDAYTKKLNEQVAQEEPLKDLLHLPELFSPGMLVRCVVNSVGITERGKRSVKLS
LNPRNVNRVLSAEAL
PF00575 // ENSGT00390000012228_0_Domain_0 (196, 268)
KPGMLLTGTVSSLEDHGYLVDIGVDGTRAFLPLPKAQEYIRQKNK
GAKLKVGQYLNCVIEEVKGNGGVVSLS
ENSGT00390000012228_0_Linker_0_1 (268, 468)
VGHAEVSTAIATEDQNWTLNNLLPGLVVKAQVQ
KVTPHGLTLNFLTFFTGLVDFMQLDPKKAGTYFSNQAVRACILCVHPRTRVVRLSLRPIF
LQPGRPLTRLSCQHLGAVLDDVPVQGFFNKAGATFRLKDGILAYARL------SHLSDSK
NTFKPESFKPGNAHKCRIIDYSPMDELALLSLRTSIIEAQYLRYHDI
PF00575 // ENSGT00390000012228_0_Domain_1 (468, 538)
KPGAVVKGTVLTI
KPYGMLVKVGQQIRGLVPAMHLADILIKNPEKKYHVGDEVKCRVLLCDPEAKKLMMTLKK
TLVESTLPAITCYADAKPGLQTHGFIIR--------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------LLCRKPALVSTVESGQDPKNFSEIHPGM
PF00575 // ENSGT00390000012228_0_Domain_4 (756, 823)
LLVGFVKSIKDYGVFIQFPSGLSGL
APKAIMSDKFVTSTSDHFVEGQTVVAKVTNVDEEKQRMLLSLRLSDCALGDLAAASLLLL
RQCLEELQGVRSLMR--NR-DSVLIQTLAEMTAGMVLDLVVQEVLEDGSVLFSGGPVPGL
-VLRASKYHRAGQEVESGQKKKVVILNVDMLKLEVHVSLHQDLVNRK-AKKVSLL-----
----------LISISM--DGHFSCFCLLAI------------------------------
------------------------------------------------------------
-------------------------------VNS--------AALNM-----------GV
QISLLFLPISHPRFLRTIPELSVRPSELE------DGHTALNSHSVSPVEKIKQYQAGQT
VTCFLKKYNVVKKWLEVEIAPDIRGRIPLLLTSLSFKVLKHPDK-KFQIGQA-LRATVVG
PD-SSKAFLCLSL-IGPHKLEKGEVAMGRVAKVTPNEGLTVSFPFGKIGRVSIFHVSDSY
SETPLEDFVPQKVVRCYVLSTADEVLTLS---LRSSRTNPETKSKIEDPEINSIQDIKKG
QLLRGYVRSVQ-PHGVLFGLGPSVVGLAQYPHVSQYSPSKKTLYNKYLPEGKLLTAKILS
----------------LNHQKNLVELSFLPSDTGKPDVLSASMELPLSKQEARKIEAEER
DQKGEEKNQKRK-----E-K-KSQKGQAE--ARLSNK---------EKTQGKRL-RT-PA
SE----------------RVSPSG-GLWAGAGDRE------------QAEPRA-FLSASV
------------------------------VLQEKPTKPAEAPRLQLPSGFAWNVGLDSL
TP-ALPPRGESSDSEEDE-KPHQATK--KKSKKERDLEKQKAEKELSRVEEALMDPRRQP
ESADDFDRLVLSSPNSSILWLQYMAFHLQATEIEKARAVAERALKTISFRLEEQEKLNVW
VALLNLENMYGSQESLSKVFERAVQYNEPLKVYLHLADIYTKSEKLQEAGELYNRMLKRF
RQEKA
PF05843 // ENSGT00390000012228_0_Domain_7 (1866, 2008)
VWIKYGAFLLRRSQAGASHRVLQRALECLPSKEHVDVITKFAQLEFQLGDAERAK
AIFENTLSTYPKRTDVWSVYIDMTIKHGSQKEV-RDIFERVIHLSLVPKRMKFFFKRYLD
YEKQHGTEKDVQAVKAKALEYVEAKSSVLEE--
ENSPCAP00000011076 (view gene)
----------------------------------------DSTEEEPTKRK-KSQKGPAK
T----K-LKTEKREN-IKPAEKFEILSVEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXDLVCLRELFSPGMLVRCVVSSLGITEKGRKSVKLS
LNPKNVNGVLSAEALKPGMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------XXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXX
XXXXXXXXVMKVVVLNCEPARERMFLSCKLLSGPDAKRGHER-G-SQKKRRAIDVGQLVD
VKVVEKTKDGLEVAVLPH--NVPAFLPTPHLSDHVPNGPLLYHWLQAGDTLHRVL---CL
QSEGRVXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXKFVTSTSDHFVEEQTVVAKVTNVDEEKQRM-LSLRLSDCTLADVAPASLLLL
SQCLEELQGVRSLMS--NRE-SVLIQTLAEMTPGLILDLEIQEVLEDGSVVFSGGPVPGL
-VLRASKYHRAGQEVEPGQKKKAVILNVDMLKLEVHVSLCPDLVSRK-HKKLKKGGEYQA
TVQHLEESFAVASLLE--TGQLAAFSLTSHLNDTFRFDSEKLQVGQGVSLTLRTTQPGVT
GLLLAVEGPAAKRTMGQTQKDSAMMDADEE-A------DPA----LVVGTVKKH
PF00575 // ENSGT00390000012228_0_Domain_5 (1075, 1150)
TLSPGD
MVTGTVKSVKPTHVVVTLEDGVTGCIHASHILDDVPVGTSPTSKLKVGKTVTARVIGGRD
VKTFKFLPISHPRFIRTIPELSIRPSELE-----NDGHTALNTHSVSPSEKIKQFQVGQT
VTCFLKKYNVVKKWLEVEIAPDVRGRIPLLLTSLSFKVLKHPDK-KFQIGQA-LQATVVG
PDSSKA-FLCLSL-IGPHKLEKGEVAMGRVVKVIPSEGLTVSFPFGKFGRASIFHLSDSY
SETPLEDFVPQQIVXXXXXXXXXXXXXXX---XXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXX-XXXXXXXLGPSVVGLARYSCVSQYSPSKKDLYSRYLPEGKLLTAKILS
----------------LNHKRSLVRLSFLPSDTGKPDVLPASVGLLLQEQEQGEAEADRG
DQKG------KEAKKNQ--KRQEEAR-------QPSK-----------EKSEPQKLQVKK
QGKREHPEFESK----Q--ERVTKKQKKAVLTEED----DSGVEVYYREGEEDIQEMTVV
P-------------------------------KEKPTKPTEAPRLQLSSGFMWDVGLDSL
TP-ALPPRGESSDSEEDEK-PHEATK--KKSRKEKALQKQKAEKELSRIEEALMDPGRQP
ESADDFDRLVLSSPNSSILWLQYMAFHLQATEIEKARAVAERALKTISFRE-EQEKLNVW
VALLNLE-MYGSRESLTKAFERAVQYNE-LKVFLHLADILRKSEKFQEAGELYNRMLKRF
RQEKAVWIKYGSFLLRRGQAGASHRLMQRALECLPQKEHVDVIAKFAQLEFQLGDAERAK
AIFENTLSTYPKRTDVWSVYIDMTIKHGSQKEV-RDIFERVIHLSLAPKRMKFFFKRYLD
YEKQHGSDKDVQAVKAKALEYVEAKSSVLED--
ENSMICP00000011350 (view gene)
-MATLEESFPRGGTRK--IHKSEKAFQQSVEQDNLFDIS---TEEKSTKRK-KSQKGPAK
T----KKLKIEKRESSKSVREKFEILSVESLCEGMRILGCVKEVNELELVISLPNGLRGF
VQATEICDAYTKKLNEQVAQEEPLKDLLQLPELFSPGMLVRCVVSSVGITERGKRSVKLS
LNPKNVNRVLSAEAL
PF00575 // ENSGT00390000012228_0_Domain_0 (196, 268)
KPGMLLTGTVSSLEDHGYLVDIGVEGTRAFLPLPKAQEYIRQKNK
GAKLKVGQYLNCVIEEVKGNGGVVSLSVGHAEVSTAIATEEQNWTLNNLLPGLVVKAQVQ
KVTPHGLRLNFLTFFTGLVDFMHLDPKKAGTYFSNQAVRACILCVHPRTRVVRLSLRPIF
LQPGRPLTRLSCQHLGAVLDDVPVQGFFNKAGAIFRLKDGILAYARL------SHLSDSK
NTFKPESFKPGNTHKCRIIDYSQMDELALLSLRTSIIEAQYLSYHDIKPGAVVKGTVLTI
KPYGMLLKVGQHIRGLVPAMHLADILIKNPEKKYHAGDEVKCRVLLCDSEDKKLMMTLKK
TLVESKLPAITCYADAKPGLQTH
PF00575 // ENSGT00390000012228_0_Domain_3 (564, 628)
GFIIRVKDYGCIVKFYNDVQGLVPKHELSA-EYIPDP
ERVFYTGQVVKVVVLNCEPSKERMLLS
ENSGT00390000012228_0_Linker_3_4 (628, 759)
FKLLSDPELQKE--PAGHSQKKGRVINVGQLVD
VKVLEKTKDGLEVTILPY--NIPAFLPTPHLSDHVANGPLLYHWLQAGDTLHRVL---CL
SRSEGHILLCRKPALVSTVEGGQDPKNFSEIHPGMLLI
PF00575 // ENSGT00390000012228_0_Domain_4 (759, 823)
GFVKSIKDYGVFIQFPSGLSGL
APKAIMSDKFVTSTSDHFVEGQTVVAKVTNVDEEKQRMLLSL
ENSGT00390000012228_0_Linker_4_5 (823, 1077)
RLSDCALGDLAATSLLLL
SQCLEELQGVRSLMR--SR-DSVLIQTLAEMTAGMVLDLVVQEVLEDGSVLFSGGPVPGL
-VLRASKYHRAGQEVESGQKKKAVILNVDMLTLEVHVSLHQDLVNRK-AKKLKKDSEHQA
IVQHLEESFAVASLVE--TGHLAAFSLTSHLNDTFRFDSEKLHIGQGVSLTLKTTEPGVT
GLLLAVEGPAAKRTMRQTRKDSETVDEDE-----------EVDPALAVGTVKKHTL
PF00575 // ENSGT00390000012228_0_Domain_5 (1077, 1141)
SIGD
MVTGTVKSIKPTHVVVTLEDGVIGCIHASHILDDVPEGISPTTKLKVGKTVTARVIGGRD
MKTYKFLPISHPRFLRTIPELSVRPSELE------DGHTALNSHSVSRMEKIKQYQAGQT
VTCFLKKYNVVKKWLEVELAPDIRGRIPLLLMSLSFKVLKHPDK-KFQIGQA-LRATVVG
PD-SSKAFLCLSL-IGPHKLEKGEVAMGRVAKVTPNEGLTVSFPFGKIGRVSIFHVNDSY
SETPLEDFIPQKVVRCYVLSTEDEVLTLS---LRSSRTNPETKSKIEDPEINSIRDIKKG
HLLRGYVRSVQ-PDGVLVGLGPSVVGLAQYPHVSQCSPSKKTLYNKYLPEGKLLTAKILS
----------------VNHQKNLVELSFLPSDTGKPDVLSASMELPLSKQEERKIEAKER
DQKGEEKNQKRK-----E-K-KNQKGQAA-AARLPSK---------EKTQGKRELQT-PV
SE----------------QERVNKKAKKAGPSEED----DSGMEVYYREGEEA-MEEMDM
------------------------------LPKEKPPKPAEAPRLQLPSGFAWNVGLDSL
TP-ALPPRGESSDSEEDE-KPHQATK--KKSKKERDLEKQKAEKELSRVEEALMDPRRQP
ESADDFDRLVLSSPNSSILWLQYMAFHLQATEIEKARAVAERALKTISFRE-EQEKLNVW
VALLNLENMYGSQESLNKVFERAVQYNEPLKVYLHLADIYTKSEKLQEAGELYNRMLKRF
RQEKA
PF05843 // ENSGT00390000012228_0_Domain_7 (1866, 2008)
VWIKYGAFLLRRSQAGASHRVLQRALECLPSKEHVDVITKFAQLEFQLGDAERAK
AIFENTLSTYPKRTDVWSVYIDMTIKHGSQKEV-RDIFERVIHLSLAPKRMKFFFKRYLD
YEKQHGTEKDVQAVKAKALEYVEAKSSVLEE--
ENSCAPP00000002433 (view gene)
------------------------------------------------------------
-----------------------------SLCKGMRILGCVKEVNELELVIGLPNGLQGF
VQVTEICDAYTQKLNEQVAQEEPLKVRKIW------------------------------
-----------------MKPLGGTVSSLEDHGYLVDIGVEGTRAFLPQQKAQEYIRQKNK
GEGQKRGC----------------------------------------------------
---------------------------------LHIWVRACVLCVHPRTRAVRLSLRPIF
LQPGRPLTRLSCQHLGAVLQDVPVQGFFNKAGATFRLKDGALAYARL------SHLSDSK
NGFRPEAFKPGNTHKCRIIDYSQMDELALLSLRTSVIEAQYLKYHDIKTGAVIKVRP---
KPY-----TDSLVLGLVPAMHLADIPMKNPEKKYHVGDEVKCRVSPCSTAGITSS-----
---------RACEATAS----------------------------------------VGG
HAAVVTCQVVKVAVLNCEPSRERMLLSFKLLSDPERKNG--SVERRQKSKKAISVGQLVD
VKILEKTKDGLHVAVLPH--NIPAFLPTPHLSDHVTNGPLLYHWLQAGDTLHRVL---CL
SQSEKQVLLCRKPALVSAVEDGQVPKSFSEIQ
PF00575 // ENSGT00390000012228_0_Domain_4 (753, 822)
PGMLLVGFVKSIKDYGVFVQFPSGLSGL
APKAIMSDKFVTNPSDHFVEGQTVVVKVTKVDEEKQRMLVS
ENSGT00390000012228_0_Linker_4_5 (822, 1078)
LRLSDCRLGSSSSTSLLLL
SQCLEELHGVRSLMG--SQ-DSVLIQTLAKMTPGMVLDLVVQEVLEDGSVVLSGGPVPDL
-VLRASRYHRAGQEVEAGQKRKAVILHVDMLELEVHVSLLKELVNRK-ARKLKKGRKYQA
TVQHLEESFALASLVE--TGHLVAFSLASHLNDTFRFDSEKLQVGQGVCLVLKTTEPGVT
GLLLAVVGPAAQRVLRQTRKDSETVDDDE-----------EGDPALVTGLRRQHTLA
PF00575 // ENSGT00390000012228_0_Domain_5 (1078, 1142)
LGD
TVTGTVKSVKPTHVVVTLEGGLVGCIHASHILDDVVEGSMPTATLKVGQSVTARVIGGRD
VKTSKFLPISHPRFIRTIPELSIRPSELE------QGHTALDTYSASPGEKIEHYQAGQT
VTCFLKKYNVVKKWLEVDVAPDIRGRIPLLLASLSFKVSHHRNF-F-SVLLA-SSRFLV-
-H-SSPQIGFILL-AGPHKLEKGEVAMGRVVKVTPHKGLTVAFPFGRTGTVSVFHMSDSY
SETPLEDFMPQKVV----------------------RTNPETKSKVEDPEINSMQDVKAG
QLLRGYVQSIE-PSGVLLGMLRCTVPLGY------------------IP-----------
RTPSALVPPSLSSCCRLNHNKNLVELSFLPTDTGRPDVLSVSPELPLQKQEEDRKE-E--
--------S------QQRKEKKNPKGQK--EGKLPNK---------EQTEVKRL------
-GKRERQDSEGVRER------VNKRQKKANLLEED----DSGVEVYYREGEEEIEET---
--------------------------------KVLLRVRAKVPRLRLSSGFLWDVGLDSL
TP-ALPPRGESSDSEEDE-KPHQAMHK-KKSKKERELEKQQSEKELSRIEEALMDPRWQP
GSADDFDRLVLSSPNSSILWLQYMAFHLQATEIEKARAVAERALKTISFRE-EQEKLNVW
VALLNLENMYGSPESLSKVFERAVQYNEPLKVFLHLADIYAKSEKFQEAGELYNRMLKRF
RQEKA
PF05843 // ENSGT00390000012228_0_Domain_7 (1866, 2008)
VWVKYGAFLLRRSQAGACRRVLQRALECLPTKEHMDVITKFAQLEFQLGDAERAK
AIFENMLSTYPKRTDVWSVFIDLTIKHSSQKEI-RDLFERVIHLSLAPKKMKFFFKRYLD
YEKQHGTEKDVLAVKAKALEYVEAKSSVLED--
ENSTBEP00000001696 (view gene)
-MATLEESFPRGGTRK--THKPEKAFQQSIEQDNLFDIS---NEEESTKRK-KSQKGPAK
T----KKLKIEKKESSKSLREKFEILSVESLCEGMRILGCVKEVNELELVISLPNGLLGF
VQVTEICDAYTAKLNEQVAQEEPLKDLLSLPELFSPGMLVRCVVSSLGITERGKKSVKLS
LNPKNVNSVLSAE
PF00575 // ENSGT00390000012228_0_Domain_0 (194, 269)
VLKPGMLLTGTVLSLEDHGYLVDIGVSGSRAFLPLQKAQEYIRQKNK
GTNLKMGQYLNCVIEEVKGNGGVVRLSVGHSELSAAIATEEQNWTLNNLLPGLVVKAQVQ
KVTPFGLTLSFLTFFTGLVDFMHLDPKKAGTYFSNQPXXXXXXXXXXXXXXXXXXXXXXF
LQPGRPLTVS-CNG----VLNDPVQGFFSKAGAIFRLKNG-LAYARL------SHLSDSK
NLFNPEAFKPGNTHKCRVIDYSQMDGLPLLSLRTSVIEAQYLRYHDIKPGAVVKGKVLTI
KPYGMLVKVGEQMRGLVPPMHLADILMKNPEKKYRVGDEVKCRVLLCDPEAKRLMMTLKK
TLVESTLPTITCYA
PF00575 // ENSGT00390000012228_0_Domain_3 (555, 629)
DAKPGLQTHGFVFRVKDYGCIVKFYSNVQGLVPRHELST-EYIPDP
ERFFYTGQVVKVVVLNCEP-KERMLLSF
ENSGT00390000012228_0_Linker_3_4 (629, 750)
KLSSGLEA----ERAGHSQKKGRSVNIGELVD
VKVSEKTKDGLQVTVLPY--HLPAFLPTPHLSDHVANGPLLCHWLQAGDTLHRVL---CL
SQSEGRVLLCRKPALVSTVEGGQDPKTFS
PF00575 // ENSGT00390000012228_0_Domain_4 (750, 823)
EIQPGMLLIGFVKSIKDYGVFVQFPSGLSGL
APKAIISDKFVTSTSDHFVEGQTVVAKVTNVDEGKQRMLLSL
ENSGT00390000012228_0_Linker_4_5 (823, 1075)
RLSDCSLGDPATTSLLLL
SQCLEERQGVRSLMG--SR-DSVLIRTLAEMIPGMILDLIVQEVLEDGSVVFSGGPVSDL
-VLRASKYHRAGQEVESGQKKKVVVLNVDMLKLEVHVSLQQDLVNRK-MKKLRKGSEYPA
IVQHLEESFAIASLAE--TGHLAAFSLISHLNDTFRFDSEKLQVGQGVSLTLKTTDPGMT
GLLLAVEGPAAKRTMRQPRKDSETVDEDE-----------EVDPALAVGTVKKH
PF00575 // ENSGT00390000012228_0_Domain_5 (1075, 1150)
TLSIGD
MVTGTVKSIKPTHVVVTLEDGIIGCIHASHILDDVPEGTSPTSKLKVGKTVTARVIGGRD
MKTFRFLPISHPRFIRTIPELSVRPSELE-----EDGHTALNTHSVSPAEKIKQYQAGQT
VTCFLKKYNVVKKWLEVEITPDIRGRIPLLLASLSFKVLKHPDK-KFQIGQA-LKATVVG
PD-SSKAFLCLSL-IGPHKLEKGEVAMGRVVKVTPNEGLTVAFPFGKMGKVSMFHLSDSY
SEEPLQDFVPQQVVXXXXXXXXXXXXXXX---XXXXXTNPETKSKIEDPEINSIKDIKKG
QVLRGYVRSVQ-PEGVLLGLGPSVAGLAQYPHVSHRSPSKKALYDRYLPSGKLLTAKVLS
----------------LNPQKKLVELSFLPADTGKPDVLSASLELPSPKQEERKVKAEER
DQTGEDKEKKKNL---KRKEKPSQKGQV--EVKPPSK---------EKSQPRPPRV---Q
QGKRGRLESG------SEQXXXXXXXXXXXXXXXXX----XXXXXXXXXXXXX-XXXXXX
------------------------------XXXEKPTKPAEAPRLQLTSGFVWDVGLDSL
TP-ALPPRAESSDSEEDE-KPHHTTK--KKSKKERELEQQKAEKELSRVEEALMDPRRQP
ESADDFDRLVLSSPNSSILWLQYMAFHLQATEIEKARAVAERALKTISFRE-EQEKLNVW
VALLNLENMYGSPESLTKAFERAVQYNEPLKVFLHLADIYTKSEKFQEAGDLYNRMLKRF
RQEKAVWIKYGAFLLRQSQAGASHRVLQRALECLPSKEHVDVISKFAQLEFQLGDPERAK
AIFENTLSTYPKRTDVWSVYIDMTIKYGRQKDV-RDIFERVIHLSLAPKRMKFFFKRYLD
YEKQHGTEKDVQAVKAKPLEYVKAKATVLED--
ENSDNOP00000010747 (view gene)
-MATLEESFPRGGTRK--IHKSEKAFQQSVDKDNLFDIS---TEEESTKRK-KSQKRPAK
I----KKLKIENREMSKSVTEKFEILSVESLCEGMRILGCVREVKDLELVISLPSGLQGF
VKVTEICDAYTKKLNEQVAHEEPLKDLVRLQELFSPGMLVRCVVISLDITERGKKSVKLS
LNPKNVNGVLSAEAL
PF00575 // ENSGT00390000012228_0_Domain_0 (196, 268)
KPGMLLTSTVSSLEDHGYLMDIGVSGARAFLPLQKAQEYIRQKNK
GAKLKMGQYLNCVIEEVKGNGGVVSLS
ENSGT00390000012228_0_Linker_0_1 (268, 468)
IGHSEVSAAIATKEQNWTLNNLLPGLVVKAQVQ
KVTPFGLTLNFLSFFTGQVDFMHLDPKKTGTYFPNQPVRACILSIHPRTRVVQLSLRPVF
LQPGRSLARLSCQYLGTVLDDAPVQGYFGKAGATFKLKDGALAYARL------SHLSDAK
NFFNPENFKPGNTHRCRVIDYSQMDQMALLSLRTSVIEAQYLRYHDI
PF00575 // ENSGT00390000012228_0_Domain_1 (468, 539)
KPGEVVKGTVHTI
KPYGMLVKVDEQIRGLVPSMHLADILMKNPEKKYHIGDEVKCRVLLCDPEAKKLMLTLKK
TLVQSKLPAITCYADAKPCLQTHGFIIRVKDCGCIVKFYNDVQGLVPKHELST-EYIPDP
DSVFYPGQVVKVAVLNCEPSKERMLLSFKLSSDSKPNKE--SVRQSQKKGRAINVGQLVD
VKVLDKTKDGLEVAVLPH--NTPAFLPTTHLSDHIANGPLLYHWLQAGDILHRVL---CL
SRFEGRVLLCRKPALVSTVEGGQDPKNFSEIH
PF00575 // ENSGT00390000012228_0_Domain_4 (753, 823)
PGMLLIGFVKSIKDYGVFIQFPSGLSGL
APKAIMSDKFVTSTSDHFVEGQTVVAKVTNVDEEKQRMLLSL
ENSGT00390000012228_0_Linker_4_5 (823, 1078)
RLSDCTLGDLSTTSLLLL
SQCLEELQGVRSLMS--NR-DSVLIQTLAEMNPGMVLDLEVQEVLEDGSVVFSGGPVPDL
-VLRASRYHRAGQEVEPGKKKTAVILSVDTLKLEVHVSLCHDLVNRK-AKKLKRGSEHQA
IVQHLEESFAIASLVE--TGHLAAFSLTSHLNDTFRFDSEKLHVGQGVSLTLKTTEPGMT
GLLLAVEGPAAKRTMGQTRKESETVDEDE-----------EVDPALVVGAIKKHTLS
PF00575 // ENSGT00390000012228_0_Domain_5 (1078, 1138)
IGD
MVTGTVKSIKATHVVVTLEDGVIGCIHASHILDDVPVGTSPTVKLKVGKTVTARVIGGRD
MKTFKFLPISHPKFIRTIPELSVRPSELE-----KDGHTVLNTHSVSPLEKIKQYQAGQT
VICFLKRYNVVKKWLEVEIAPDIRGRIPLLLTSLSFKVLKHPDK-KFQIGQA-LRATVVG
PD-SSKAFLCLSL-IGPHKLEKGEVAMGRVVKVTPNEGLTVSFPFGKVGRVSIFHVSDSY
SEAPLEDFVPQQVVRCCVLSTADDVLTLS---LRSSRTNPLTKSKIEDPEINSIEDLKEG
QLLRGYVKAVQ-LNGVLLGLGPSVVGLAQYPHVSQYSLSKKALYNSYLPRGKLLTAKVLS
----------------LNYKKNLVELSFLSGDTGKLDVFSASLGQPLEKQEEKKTETEKK
DRNRNEEKNNR-K---GK-E-KNQKGQL--ELKLPHK---------EKKDPQKPLVK--K
KGNWECVESE------SEQERVSKKQKKTDLKEVDSAYREGEEAVYYREGEEE-IDEMNV
------------------------------LPKEKQAKPAEVPRLQLSSGFIWDVGLDSL
TP-ALPPGGESSDSEEDE-QPHQATQ--KKRKKERELEKQKAEKELSRLEEALMDPGRQP
ESADDFDRLVLSSPNSSILWLQYMAFHLQATEIEKARAVAERALKTISFRE-EQEKLNVW
VALLNLENMYGSQESLTKVFERAVQYSEPLKVFLHLADIYTKSEKFQEAGELYNRMLKRF
RQEKAVWVKYGAFLLRRGQAGANHRVLQRALECLPNKEH
PF05843 // ENSGT00390000012228_0_Domain_7 (1900, 2008)
VDVIAKFAQLEFQLGDAERAK
AIFENTLSTYPKRTDVWSVYIDMTIKHGSQKEV-RDIFERVIHLSLAPKRMKFFFKRYLD
YEKQHGTEKDVQAVKAKALEYVEAKSSVLED--
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