ENSGT00390000011587_1 : Linker Region Query Results

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---------------------------------------------------MSRRSQRLT
---RYS-QGDDDGS-SSSGGSSVTGSQSALFKDSPLRTLK-RKSS--NMKRLSPAPQLGP
SSDAHTSYYSES--MVRESYVGSPRAAAL------ARSA-LD-D-LHSDPYWS-------
---------------------------------------------------EDLLVRRRR
GT--GGTESSKVNGLA-ES-KVSEDFLGSSSGYSSEDDYLGYS-----------------
---------DTDQQSSGSR---IRSAVSRAG--SFLW-----------------------
------MVVTSPGRLFGLFYWWVGTTWYRLT-TAASLLDVFVLTRR--FS----SLKTF-
LRFLLLLLLLTCLTYGA--WYFYPYGLQTLHPAVVSWWAAKD----SRRQHEGWGSRDS-
PH---LQAEPHILSQL--HSLERRLEALAAEFSSNWQKEALRLER-LELRQGAAGQGG--
------SGGLSHED-----------TLALLEG--L--VSRR------E-AALKEDLRRDT
A---------------------S-----RMQEELAT---LRAEHQQDAEDLFKKIVQASQ
ESEARIHQLKSEW----Q--RMTQESFRESSM--KELGRLEDQLAGLRQELAALALKQST
VADEVGLLPQQIQAVRD-------DVESQFPAWISQFL-LR----G---GGTRTGL-LQR
EEMQA-----QLQELESKIL-AHVAQMQG-----KSAREAAASLGLTLQKEGVIGVTEEQ
-----------------------VH----RIVKQALQ-RYSEDRIGMVDYALE-------
-----------------SG--GASVIS--TRCSETYETKTALLSLFGIPLWYHSQSPRV-
ILQPDVHPGNCWAFQGPQGFAVVRLSARIRPTAVTLEHVPKA-LSPNSTISSAPKDFAIF
G-----------------F-----DEDLQ-QEGTLLGKFTYDQD-GEPIQ--TFHF--QA
PE--MAT------YQVVELR-------ILTNWGHPEYTCIYRF-RVHGEPAH--------
------------------------------------------

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---------------------------------------------------MSRRSQRLT
---RYS-QGDDDGS-SSSGGSSVAGSQSTLFKDSPLRTLK-RKSS--NMKRLSPAPQLGP
SSDAHTSYYSES--LVRESYIGT---GFP------PRSS-LE-E-LHGDANWG-------
---------------------------------------------------EDLRVRRRR
GT--GGSESSRASGLV-GR-KAAEDFLGSSSGYSSEDDYV--------------------
-----GYS-DADQQSSSSR---LRSAVSRAG--SLLW-----------------------
------MVATSPGRLFRLLYWWAGTTWYRLT-TAASLLDVFVLTRR--FS----SLKTF-
LWFLLPLLLLTCLTYGA--WYFYPYGLQTFHPALVSWWAAKD----SRRQDEGWESRDSS
PH---FQAEQRVMSRV--HSLERRLEALAAEFSSNWQKEAMRLER-LELRQGAPGPGG--
------GGGLTHED-----------TLALLEG--L--VSRR------E-AALKEDFRRET
A---------------------A-----RIQEELST---LRAEHQQDSEDLFKKIVQASQ
ESEARIQQLKSEW----Q--SMTQESFPESSV--KELRRLEDQLAGLQQELAALALKQSS
VADEVDLLPQQIQAVRD-------DVESQFPAWISQFL-AR----G---GGGRVGL-LQR
EEMQA-----QLRELESKIL-THVAEMQG-----KSAREAAASLGLTLQKEGVIGVTEEQ
-----------------------VH----HIVKQALQ-RYSEDRIGLADYALE-------
-----------------SG--GASVIS--TRCSETYETKTALLSLFGIPLWYHSQSPRV-
ILQPDVHPGNCWAFQGPQGFAVVRLSARIRPTAVTLEHVPKA-LSPNSTISSAPKDFAIF
G-----------------F-----DEDLQ-QEGTLLGKFTYDQD-GEPIQ--TFHF--QA
PT--MAT------YQVVELR-------ILTNWGHPEYTCIYRF-R------VHGEPAH--
------------------------------------------

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---------------MSAQPTLRRGVGFFQGSPE----EAGCSAS----FRGLLPEP---
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E---------------------N-----PE---APRIPRSWKMT----------LALLF-
--------------------------------------MLSFLLIX------XXXXXXXX
XXXX-XXXXXXXXXXXX-------XXXXXXXXXXARLR-MP----KEHLELLKKESQTLE
SNFREILFLIEQTEALKMLL-RDVQEGAHNL---SWKVTGDTL-----TGDQDA---AE-
--------------------------EMSNLVNYVLK-KLREDQVQMADYALK-------
-----------------SA--GASIIE--SGTSESYKNDKAKLYWHGIGFLNYEMPPDT-
ILQPDVHPGKCWAFPGSQGHTLIRLARRITPSAVTIEHISEK-VSPSGNISSAPKDFSVY
-----------------GI-----LRKCE-GEEMLLGRFTY-NKTDSTVQ--TFAL--QR
QV----------------------------------------------------------
------------------------------------------

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------------------------------------------------------MDVSF-
SLLPDISPGSCWAFQGSQGHVVIRLPEKIQPRAFTIWHISRA-VSPCGEVSSAPEEFAVS
V-----------------S-----LCL-----------LLL-LLEGPRAR--GRAL--PE
MS-----------FWW--------------------------------------------
------------------------------------------

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------------------------------------------------------MDVSF-
SLLPDISPGSCWAFQGSQGHVVIRLPEKIQPRAFTIWHISRA-VSPCGEVSSAPEEFAVS
V-----------------S-----LCL-----------LL--LLEGPRAR--GRAL--PE
MS-----------FWW--------------------------------------------
------------------------------------------

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-----------------------------------------------------LQKYVWL
EETDFPQNSRRLHAVIA-------EYSSRLYNYQXXXX-XX----XXXXXXXXKESQTLE
NNFREILLLIEQIDALKALL-RDMKEGMHNH---SWNAIEDPA-----EEENKE----E-
--------------------------EMSNLVNYVLK-KLREDQVQMADYALK-------
-----------------SAXXXXXXXX--XXXXXXX--XXXXXXXXXXXXXXXXXXXXX-
XXXPDVHPGKCWAFPGSQGHTLIKLARKIIPTAVTMDHISEK-ISPSGNTSSAPKEFSVY
-----------------GI-----SKECE-GEEIFLGQFIY-NKGGTTVQ--TFEL--QH
EV--SEY------LLCVKLK-------ILSNWGHPTYTCLYRF-RVHGNPGNHT------
------------------------------------------

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------------------------------------------MP----------------
------------------------------------------RSR----------NTG--
-----D-LCVQPED-----------TSHCTRP--R----R-S--------MFL-WSVFSA
D-D-ASLLFS---------GINS-PGPSLTQFILGY--MSWLTC----------L-ACFL
RTQAQQV----------LLNTCRCKLLCQKLM--EKIGLLVLCAFG-----------FWM
FSMHLPSKMEVWQDDS---------INSPL----QSLR-MY----QEKVRHHTGEIQDLR
GSMN-------------QLI-AKLQEMEA--------------------------MSDEQ
K-----------------------------MAQKIMK-MIQGDYIEKPDFALK-------
-----------------SI--GASIDF--EHTSATYNHDKARSYWNWIRLWNYAQPPDV-
ILEPNVTPGNCWAFAGDRGQVTIRLAQKVYLSNLTLQHIPKT-ISLSGSLDTAPKDFVIY
-----------------GM---E---S-PPREEVFLGAFQF-QP-ENTIQ--MFPL--QN
QP--PRG------FAAVKVK-------ISSNWGNPRFTCLYRV-RVHGSVTPPRDSHLA-
PLS---------------------------------------

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---------------------------------------------------MSRRSQRLT
---RYS-QGDDDGSSS-SGGSSVMGSQSTLFKDSPLRTLK-KKSS--NMKRLSPAPQLGP
SSDAHTSYYSES--VVRESYIGSPRAAAL------ARSSIFD-DQLHGDSYWS-------
---------------------------------------------------EDLRVRRRR
GT--GGTESSKINGLA-EN-KLSEDFFGSSSGYSSEDDYA--------------------
-----GYS-ETDQRSSGSR---LRSAVSRAG--SFFW-----------------------
------MVVTSPGRLFGLLYWWVGTTWYRLT-TAASLLDVFVLT--RRFS----SLKTF-
LWFLLLLLLLTGLTYGA--WYFYPYWLQTFHPAVVSWWAGKG----NSQQHEVWESRESS
PQ---FQAEQRLLSRV--HSLERRLEALAAEFSSNWQKEAMRLER-LELRQGATGQG---
-----GSGSLSHED-----------TLGLLEG--L--VSRR------E-AALKEDFRRDT
A---------------------A-----RIQEELVT---LRAEHQQDLEDLFKKIVQASQ
ESEAQLQQLKSEW----Q--RMTQESFRENSM--KELGRLEGQLAGLRQELAALTLKQSS
VVDQVDLLPQQIQAVRD-------DVESQFPAWVSQFL-LR----G---GGTRAGL-LQR
EEIQA-----QLQELESKIL-AHMAEMQG-----KSAREAAASLGLTLQKEGVIGVTEEQ
-----------------------VH----RIVKQALK-RYSEDRIGMVDYALE-------
-----------------SG--GASVIS--TRCSETYETKTALLSLFGIPLWYHSQSPRV-
ILQPDVHPGNCWAFQGPQGFAVVRLSARIRPTAVTLEHVPKS-LSPNSTISSAPKDFAIF
G-----------------F-----DEDLQ-QEGTLLGQFTYDQD-GEPIQ--TFYF--QD
PK--MAT------YQVVELR-------ILTNWGHPEYTCIYRF-RVHGEPAH--------
------------------------------------------

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---------------------------------------MRRSPRP--------------
------------GSAA-SHKH---TPNFYSDNSNSSVSTTSGDSS--GH-RSAGPGPGEP
EGR--RAQGSSCGEPALSSGVPGGTARAGSSRQKPALRSHSAP----TAEGAAT-VRG-G
A-SEPAGSPV--VSEE---RFNLLSTLDLRQEMRSP-RVFKSF-----------LNPLF-
----QVLSVFLSLLGEVLVT--VYREVCSIRFLLTAVSLLSLFLTA----------LWWG
LLYLVPPLESEP-E------------MLTIS--------EY----HERVRTQGQQLQQLQ
AELDQ-------------LH-KEVSSVRA--------------------------ANSE-
-----------------------------RVAKLVFQ-RLNEDFVRKPDYALS-------
-----------------SV--GASIDL--EKTSRDYEDANSAYFWNRFSFWNYARPPMV-
ILEPDVFPGNCWAFEGDQGQVVIRLPGRVQLSDITLQHPPPS-VAHTGGANSAPRDFAVY
G-----------------L-----QVDD--ETEVFLGKFTF-DMEKSEIQ--TFHL--QN
DP--PTA------FPKVKIQ-------ILSNWGHPHFTCLYRV-RAHGMRTTEEAGDSAT
G--GPN------------------------------------

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---------LTPVIPGAERGEAGGSPEIGTRSGGACLQEN-------------R-LNP-G
GGA--------------------------HPTLPEP-QAHSHP-----------CLSLP-
----WVLSVLLSLAGDVLVS--MYREVCSIRFLFTAVSLLSLFLAA----------IWLG
LLYLVSPLENPTPR-R---------PPPTSS--------EY----HERVRSQGQQLQQLQ
AELDK-------------LH-KEVSTVRA--------------------------ANSE-
-----------------------------RVAKLVFQ-RLNEDFVRKPDYALS-------
-----------------SV--GASIDL--QKTSHDYADRNTAYFWNRFSFWNYARPPTV-
ILEPHVFPGNCWAFEGDQGQVVIQLPGRVQLSDITLQHPPPS-VEHTGGANSAPRDFAVF
G-----------------L-----QVDD--ETEVFLGKFTF-DVEKSEIQ--TFHL--QN
DP--PAA------FPKVKIQ-------ILSNWGHPRFTCLYRV-RAHGVRTSEGAEDSAT
G--GPH------------------------------------

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--------------------------V--ERTSKSYGGNRWL----SP-FFSSAKPPET-
ILQPDISAGNCWAFQGSRGHVVIRLPEKIWPTAFTIWHISKA-VSPSGEVSTAPREFAVS
G-----------------V-----DED-E-GEA-LLGSFIY-DVDGEIAQ--TFPV--QE
EP--RKA------FRQIKLE-------VRSNWGNKEYTCVYRA-DVHGHPEKK-------
------------------------------------------

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---------------------------------------------------MSRRSQRLT
---RYT-QGDDDGGSSSSGGSSITGSQSTLFKDSPLRTLK-RKSS--SMKRLSPAPQLAP
SSDPHTSYYSES--VIKESFVGSPRAASLARSALLDRCSILD-DQLHSDPYWS-------
---------------------------------------------------EDLRVRRRR
GT--GSTESSRINGLV-ES-KRSEDFLGSSSGYSSEDDYV--------------------
-----GYSAEMDQQNSGSR---LRNAVSRAG--SFLW-----------------------
------MVVSSPGRLFGLLYWWVGTTWYRLT-TAASLLDVFVLTRSRRVS----SLRTF-
LWFLLLLLLLTCLTYGA--WYFYPYGLQTFQPAVVSWWAAKG----HSRQHEVWEPRDSS
SH---FQAEQRILSQV--HSLERRLEALAAEFSSNWQKEALRLER-LELRQGAAGEGGD-
----GGGGGLSHED-----------TLVLLEG--L--VSRR------E-AALKEDFRRDM
A---------------------A-----RIQEELVA---LRAEHQQDSEDLFKKIVQASQ
ESEARLQQLKSEW----Q--RMTQESFQENSL--KELGRLEGQLAGLQQELAALALKQGS
VEDRVDQLPQQIQAVRD-------DVESQFPAWIAQFL-LR----G---GGARAGL-LQQ
EEIEA-----RLQELESRIL-AHMAETQG-----KSVKEAAASLGLMLQKEGMIGVTEEQ
-----------------------VH----HIVSQALK-RYSEDRIGMVDYALE-------
-----------------SG--GASVIS--TRCSETYETKTALLSLFGIPLWYHSQSPRV-
ILQPDVHPGNCWAFQGPQGFAVVRLSARIRPTAVTLEHVPKS-LSPNSTISSAPKDFAIF
G-----------------F-----EEDLQ-QEGRLLGKFTYDQD-GEPIQ--TFYF--QD
PT--MAT------YQVVELR-------ILTNWGHPEYTCIYRF-RVHGDPAH--------
------------------------------------------

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------------------------------------------MP----------------
--------------R---------------------------SSR----------NPV--
-----G-QPGN------------------------------L------------------
--CNG-----------------------THFPPVST--AAWFNC----------L-ACFL
RTQAQQV----------LFNTCRCKLLCQKLM--EKTGVLLLCALG-----------ASP
G------PCPVWDSCF------------HS----FLIR-LY----QEKVRHHSGEIQDLR
GSVN-------------LLI-AKLKEMEA--------------------------MSDEE
K-----------------------------LTQKIMK-MIQGDYIEKPDFALK-------
-----------------SI--GATIDF--EHTSATYNHDKARSYWNWIRLWNYAQPPDV-
ILEPNMTPGNCWAFEGDRGQVTIRLAQKVYLSNITLQHIPKT-ISLSGSLDTAPKDFVVY
-----------------GM---E---S-SPGEEVFLGAFQF-QP-ENIIQ--MFPL--QN
PQ--QRA------FGAVKVK-------ISSNWGNPRFTCLYRV-RVHGSVAPPPRPHAGP
QPCPRD------------------------------------

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---------------------------------------MRRSPRP--------------
------------GSAASQHKH---TPNFYSDNSNSSMSVTSGDSC--GH-RSTGPGPGEP
EGR--RARGSSCGEPALSAGVPGGTTWAGSSRQKQAPRSHNGQ----TACGAAT-VRG-G
A-S---------VSEE---QLDLLPILDLRQEMPSP-QVSKSF-----------LSLLF-
----QVLSVLLSLVGDVLVS--VYREVCSIRFLLTAVSLLSLFLAA----------LWWG
LLYLAPPLEHEPKE------------MLTLS--------EY----HERVRSQGQQLQQLQ
AELVK-------------LH-REMSSVRA--------------------------ANSE-
-----------------------------RVAQLVFQ-RLSEDFVRKPDYALS-------
-----------------SV--GASIDL--EKTSQDYEDANTAYFWNRFSFWNYARPPTV-
ILEPDVFPGNCWAFEGDQGQVVIRLPGRVQLSDITLQHPPPT-VAHTRGANSAPRDFAVY
G-----------------L-----QVDD--ETEVFLGKFTF-NVEKSEIQ--TFHL--QN
DP--PAA------FPKVKIQ-------ILSNWGHPRFTCLYRV-RAHGVRTSEEAGDSAT
G--DAH------------------------------------

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------MVIGELWRFPGNSSVPYIQVEQPSLLWLALQG-S--------------------
-----------------------------------WE--ATLCPVLFLLTSTLLCLSSQA
-----------------------VQ----KIIHQVLE-KLEESPFQMTNYASK-------
-----------------TS--GAAIVR--SKTSPSWIG-SGRVFWQSLPLVAYMRPPEV-
ILEPDNHPGNCWPFPGSQGHVFIKLPVAVFPTAVTINHGVPAAAYHADSISSAPKDFAVY
G-----------------L-----QEEDD-EKGTLLGEFIF-MPGQAPGQ--TFQL--KN
EH--SAF------IKYVRLQ-------VLSNWGHPEYTCVYQF-RLHGDP----------
--APD-----------------GD-ARGKLS---A-------

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-------------GRMSARPKPRRCAWIFRVCSE----EAHGRAT----VPAMLAEQ---
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G---------------------S-----PD---ASWLIRSWKII----------LSTMF-
--------------------------------------ILIFLLVG-------LRNHVWP
NETDFPPNSGQLYAVMA-------EYGSRLYNYQVRLR-MP----KEQLELLKKESQTLE
NNFREILFLVEQIGVLKALL-RDMKDGMDNY---SWNASGEDV-----EEENNKEILEE-
--------------------------EMSNLVNYVLK-KLREDQVQMADYALK-------
-----------------SA--GASIIE--AGTSESYKNVKAKLYWHGIGFLNYEMPPDI-
ILQPDVHPGKCWAFPGPQGHTLIKLARKIIPTAVTMEHISEK-ISPSGNTSSAPKEFSVY
-----------------GI-----LKECE-GEEVFLGQFMY-NKRGTTIQ--TFKL--QH
EV--SEY------LLCVKLK-------ILSNWGHPTYTCLYRF-RVHGNPGNHT------
------------------------------------------

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------------------------------------LTGSWKII----------LSTVF-
--------------------------------------ASTFLLVG-------LLNHQWL
KETEFPQKPRQLYTVIA-------EYGSRLHNYQARLR-MP----KEQQELLKKESQTLE
NNFREILFLIEQIDLLKALL-RDMKDGVHNH---SWPAQREAV-----QDQATAEVLDE-
--------------------------EMSNLVHYVLK-KFRGDQIQLADYALK-------
-----------------SA--GASVIE--AGTSESYKNNKAKLYWHGIGFLNYEMPPDM-
ILQPDVHPGKCWAFPGSQGHILIKLARKIIPTAVTMEHISEK-VSPSGNISSAPKEFSVY
-----------------GV-----TKKCE-GEEMFLGQFIY-KKMEATIQ--TFEL--QN
EA--SES------LLCVKLQ-------ILSNWGHPKYTCLYRF-RVHGIPSDHT------
------------------------------------------

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---------------MSGKAKARRAAMFFRGCSE----DASSSTS----GNTLLSED---
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E---------------------N-----PD---ANGVTRSWKII----------LSTMF-
--------------------------------------TLIFLLVG-------LLSHQWL
KETEVPQKSRQLYAIIA-------EYGSRLYKYQARLR-MP----KE-FSLYRKESQTLE
NNFRKILLLIEQIDVLKALL-RDMKDGTDNNH--SWNTHGDPV-----EDPDHTEVLDG-
--------------------------EMSNLVNYVLK-KLREDQVQMADYALK-------
-----------------SA--GASIIE--AGTSE------TKLYWHGIGFLNHEMPPDI-
ILQPDVYPGQCWAFPGSQGHTLIKLATKIIPTAVTMEHISEK-VSPSGNISSAPREFSVY
-----------------GV-----TKKCE-GEEIFLGQFIY-NKTGTTVQ--TFEL--QH
AV--SEY------LLCVKLN-------IFSNWGHPKYTCLYRF-RVHGTPGKHI------
------------------------------------------

--------------------MPAA---QGAVWVVRIGRQP-VLSCEAIPL---SPL----
--------------------GRGWRAAPRFTPCSAFPPQSLRWKHPRPTPAMSRRSQRLT
---RYS-QGDDDGGSSSSGGSSVMGGQSTLFKDGPLRTVK-RKSG--SMKRLSPAPQLGP
SSDTHTSYYSES--VVRESYIGSPRAAAL------ARSAILE-DQLDGDSYWG-------
---------------------------------------------------EDLRMRRRR
GT--GGSESSKVNGLT-GR-KACEDFLGSSSGYSSEDDYA--------------------
-----GYS-DPEQQSSGSG---LGSAVSRAG--SFLW-----------------------
------MVATSPGRLFGLLYWWVGTTWYRLT-TAASLLDVFVLT--RRFS----SLRTF-
LWFLLLLLVLTCLTYGA--WYFYLHGLQTVYPAVLSWWAAKG----SGRQHEVWEPRDST
PH---SQVEQRLVSRV--HALERRLEALAAEFSSSWQKEALRLER-LELRQGASGQG---
-----GGGGLSHED-----------TLGLLEG--L--VSRR------E-AALKDDLRKDA
A---------------------A-----RLQEELAT---LRAEHQQDLEDLFKKIVQASQ
ESEARLQQLKSEW----Q--RLTQESFRENSM--KELGRLEGQLAGLRQELAALALRQSS
VADQVGLLSPQIQAVRD-------DVESQFPAWISQFL-LQ----G---GATRSGL-LQQ
EEMHA-----QLQELENKIL-AHVKEMQG-----KSAREAAATLGLTLQQEGVIGVSEEQ
-----------------------VH----QIVHQALK-RYSEDRIGMVDYALE-------
-----------------SG--GASVIS--TRCSETYETKTALLSLFGIPLWYHSQSPRV-
ILQPDVHPGNCWAFQGPQGFAVVRLSARIRPTAVTLEHVPRS-LSPNSTISSAPKDFAIF
G-----------------F-----DEDLQ-QEGTLLGKFTYDQD-GEPIQ--TFYF--QD
PT--MAL------YQVVELR-------ILTNWGHPEYTCIYRF-RVHGEPAH--------
------------------------------------------

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---------------------------------------------------MSRRSQRLT
---RYS-QGDDDGS-SSSGGSSVAGSQSTLFKDSPLRTLK-RKSS--NMKRLSPAPQLGP
SSDAHTSYYSES--LVRESW-------FP------PRSS-LE-E-LHGDASWG-------
---------------------------------------------------EDLRVRRRR
GT--GGSESSRASGLV-GR-KATEDFLGSSSGYSSEDDYV--------------------
-----GYS-DVDQQSSGSR---LRSAVSRAG--SLLW-----------------------
------MVATSPGRLFRLLYWWAGTTWYRLT-TAASLLDVFVLTRR--FS----SLKTF-
LWFLLPLLLLTCLTYGA--WYFYPYGLQTFHPALVSWWAAKD----SRRPDEGWEARDSS
PH---FQAEQRVMSRV--HSLERRLEALAAEFSSNWQKEAMRLER-LELRQGAPGQGG--
------GGGLSHED-----------TLALLEG--L--VSRR------E-AALKEDFRRET
A---------------------A-----RIQEELSA---LRAEHQQDSEDLFKKIVRASQ
ESEARIQQLKSEW----Q--SMTQESFQESSV--KELRRLEDQLAGLQQELAALALKQSS
VADEVGLLPQQIQVVRD-------DVESQFPAWISQFL-AR----G---GGGRVGL-LQR
EEMQA-----QLRELESKIL-THVAEMQG-----KSAREAAASLGLTLQKEGVIGVTEEQ
-----------------------VH----HIVKQALQ-RYSEDRIGLADYALE-------
-----------------SG--GASVIS--TRCSETYETKTALLSLFGIPLWYHSQSPRV-
ILQPDVHPGNCWAFQGPQGFAVVRLSARIRPTAVTLEHVPKA-LSPNSTISSAPKDFAIF
G-----------------F-----DEDLQ-QEGTLLGKFTYDQD-GEPIQ--TFHF--QA
PT--MAT------YQVVELR-------ILTNWGHPEYTCIYRF-R------VHGEPAH--
------------------------------------------

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-----------------------------------MCHPFFLGKGSASHLNMSRRSQRLT
---RYS-QGDDDGGSSSSGGSSVAGSQSTLFKDSPLRSLK-RKSS--NMKRMSPAPQLGP
SSDTHTSYYSES--VVRESYIGSPRAASL------ARSALLD-DHLHSEPYWG-------
---------------------------------------------------EDLRVRRRR
GT--GGTESSKANGLA-ES-KATEDFLGSSSGYSSEDDF---------------------
----AGYS-DMDQHSSGSS---LGNVVSRAG--SFVW-----------------------
------TVVTFPGRLFRLLYWWVGTTWYRLT-TAASLLDVFVLTRR--FS----SLRTF-
LWFLLLLLLLTGLTYGA--WYFYPFGLQTLHPAVVSWWAARD----SRRQPAVWDSRETA
PH---FQAEQRILSQV--HSLERRLEALAAEFSSNWQKESIRLER-LELRQGSTGQGG--
------GSGLSHED-----------TLALLEG--L--VSRR------E-AALKEDFRRDT
A---------------------T-----RIQEELAT---VRAEHHHDSEDLFKKIVQASQ
ESEARLQQLKSEW----Q--RMTQEAIWENSV--QELGRLEAQLTSLRQELAALSLKQSA
VEDEVGLLPQKIQAMRE-------DVESQFPAWVSHFL-LH----G---GGTRAGL-LQR
EEVQA-----QLQELESKIL-THVTEMQG-----KSAREAAALLGRTLQKEGVVGVTEEQ
-----------------------VQ----RIVKQALQ-RYSEDRIGMVDYALE-------
-----------------SG--GASVIS--TRCSETYETKTALLSLFGIPLWYHSQSPRV-
ILQPDVHPGNCWAFQGPQGFAVVRLSARIRPTAVTLEHVPKA-LSPNSTISSAPKDFSIF
G-----------------F-----DEDLQ-QEGTLLGTFTYDQD-GEPIQ--TFYF--QT
PK--MAD------YHVVELR-------ILTNWGHPEYTCIYRF-RVHGEPAH--------
------------------------------------------

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---------------MSGKAKARRAAMFFRGCSE----DASGSTS----GSTLLSED---
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E---------------------N-----PD---TNGVTRSWKII----------LSTMF-
--------------------------------------TLTFLLVG-------LLSHQWL
KETEVPQKSRQLYAIIA-------EYGSRLYKYQARLR-MP----KEQLELLKKESQTLE
NNFHKILLLIEQIDVLKALL-RDMKDGTDNNH--SWNTHGDPV-----EDPDHTE-----
--------------------------EMSNLVNYVLK-KLREDQVQMADYALK-------
-----------------SA--GASIIE--AGTSESYKNNKAKLYWHGISFLNHEMPPDI-
ILQPDVYPGNCWAFPGSQGHTLIKLATKIIPTAVTMEHISEK-VSPSGNISSAPKEFSVY
-----------------GI-----TKKCE-GEEIFLGQFIY-NKTGTTVQ--TFEL--QH
AV--SEY------LLCVKLN-------IFSNWGHPKYTCLYRF-RVHGTPGKHI------
------------------------------------------

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---------------------------------------MRRSSRP--------------
------------GSASSPSKH---TPNFFSENSSMSVT--SEDSN--GR-RSAGPGPGEP
EGR--RAQGPSCGEPALSAGVPGGTTWAGSSRQKPAPRSRNGE----TAC-GAA-TVR-G
GASEPTGSPV--VSEE---PLALLPTLDLRQEMPPP-RLSKSF-----------LSLLF-
----QVLRVSLSLAGDALVS--VYREVCSIRFLFTAVSLLSLFLAV----------IWLG
LLYLVSPLENEPK------------EMLTLS--------EY----HERVRSQGQQLQQLQ
AELDK-------------LH-KEVSTVRA--------------------------ANSE-
-----------------------------RVAKLVFQ-RLSEDFVRKPDYALS-------
-----------------SV--GASIDL--EKTSHDYADRNTAYFWNRFSFWNYARPPTV-
ILEPDVFPGNCWAFEGDQGHVVIRLPGQVELSDITLQHPPPS-VAHSGGANSAPRDFAVF
G-----------------L-----QVDD--ETEVFLGKFTF-DVEKSEIQ--TFHL--QN
DP--PAA------FPKVKIQ-------ILSNWGHPHFTCLYRV-RAHGVRTSEGAEGSAT
G--GPH------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------MRRSSRP--------------
------------GSASSSRKH---TPNFFSENSSMSIT--SEDSK--GL-RSAEPGPGEP
EGR--RARGPSCGEPALSAGVPGGTTWAGSSQQKPAPRSHNWQ----TAC-GAA-TVR-G
GASEPTGSPV--VSEE---PLDLLPTLDLRQEMPPP-RVFKSF-----------LSLLF-
----QGLSVLLSLAGDVLVS--MYREVCSIRFLFTAVSLLSLFLTL----------KAWG
PLGGVQGDREPTPR-R---------PPPTSS--------EY----HERVRSQGQQLQQLQ
AELDK-------------LH-KEVSTVRA--------------------------ANSE-
-----------------------------RVAKLVFQ-RLNEDFVRKPDYALS-------
-----------------SV--GASIDL--QKTSHDYADRNTAYFWNRFSFWNYARPPTV-
ILEPHVFPGNCWAFEGDQGQVVIQLPGRVQLSDITLQHPPPS-VEHTGGANSAPRDFAVF
G-----------------L-----QVYD--ETEVSLGKFTF-DVEKSEIQ--TFHL--QN
DP--PAA------FPKVKIQ-------ILSNWGHPRFTCLYRV-RAHGVRTSEGAEGSAQ
G--PH-------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------MSGKIKARMAAIFFRDCSE----EASGSAS----GNALLSEH---
------------------------------------------------------------
E---------------------N-----PD---ANGITRSWKII----------LSTMF-
--------------------------------------TLTFLLVG-------LLSHQWL
KETEDPQKSRQLYAIIA-------EYGSRLYKYQARLR-MS----KEQLELLKKESQTLE
NNFREILFLIEQIDVLKALL-RDMKDGMDTNH--SWSTHGDPA-----EDPDHTE-----
--------------------------EMSNLVNYVLK-KWREDQVPMADYALR-------
-----------------SA--GASIIE--AGTSESYKNNKAKLYWHGIGFLNHEMPPDT-
ILQPDVYPGKCWAFPGSQGHTLIKLARKIIPTAVTMEHISEK-VSPSGNISSAPKEFSVY
-----------------GI-----TKKCD-GEEIFLGQFIY-NKTGTTIQ--TFEL--QH
AV--SEY------LFCVKLN-------IFSNWGHPNYTCLYRF-RVHGTPGTHI------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MP----------------
--------------R---------------------------SSR----------SPG--
-----DPGAP-LED-----------VAHNPRP--R----R-IVQRGRNTSRMVEDTSSNM
N-D-NFLLPV---------RINA-QALGLTQCMLGC--VSWFTC----------F-ACSL
RTQAQQV----------LFNTCRCKLLCQKLM--EKTGILLLCAFG-----------FWM
FSIHLPSKMKVWQDDS---------INGPL----QSL-RLY----QEKVRHHSGEIQDLR
GSMN-------------LLI-AKLQEMEA--------------------------MSDEQ
K-----------------------------VAQKIMK-MIHGDYIEKPDFALK-------
-----------------ST--GASIDF--EHTSATYNHEKAHSYWNWIQLWNYAQPPDV-
ILEPNVTPGNCWAFEGNRGQVTIQLAQKVYLSNLTLQHIPKT-ISPSGSLDTAPKDFVIY
-----------------GM---E---G-SPKEEVFLGAFQF-QP-ESIIQ--MFPL--QN
QP--ARA------FGAVKVK-------ISSNWGNPAFTCLYRV-RVHGSVAPPGEQPHQN
PYPERD------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------MKMIQFSARKDLIL-DAVFHSLE--------------------ENGIDGMKREE
-----------------------IL----QLTREAVE-KVMKHDTWLPSWALK-------
-----------------TM--GATIDV--ERTSKSYGGNRWL----SP-FFSSAKPPET-
ILQPDISAGNCWAFQGSRGHVVIRLPEKIWPTAFTIWHISKA-VSPSGEVSTAPREFVVS
G-----------------V-----DED-E-GEA-LLGSFIY-DVDGEIAQ--TFPV--QE
EP--RKA------FRQIKLE-------VRSNWGNAEYTCVYRA-DVHGSPEKN-------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MP----------------
------------------------------------------RTR----------NIG--
-----A-LCTLPED-----------TTHSGRP--R----R-GVQRSSISRM-AEPAPAN-
--------------------------------------MTWLTY----------L-ACFL
RTQTQQV----------FLNTCRCKLFCQKVM--EKMGLLVLCVFG-----------FWM
FSMHLPSKVEVWQDDS---------INGPL----QSLR-MY----QEKVRHHTGEIQDLR
GSMN-------------QLI-AKLQKMEA--------------------------ISDEQ
K-----------------------------MAQKIMK-MIQGDYIEKPDFALK-------
-----------------SI--GASIDF--EHTSATYNHDKARSYWNWIRLWNYAQPPDV-
ILEPSVTPGNCWAFASDRGQVTIRLAQKVYLSNITLQHIPKT-ISLSGSLDTAPKDFVIY
-----------------GL---E---S-LPREEVFLGAFQF-QP-ENIIQ--TFQL--QN
LP--PRS------FAAVKVK-------ISSNWGNPRFTCMYRV-RVHGSVTPPKDSHLE-
PLS---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------MRRSSRP--------------
------------GSASSSRKH---TPNFFSENSSVSIT--SEDSN--GL-RSAGPGPGDP
EGR--GARGPSCGEPALSAGVPGGTTWAGSSRQKPAPRSHNWQ----TAC-GAA-TVR-G
GASEPTGSPA--VSEE---PLDLLPTLDLRQEMPPS-RVFKSF-----------LSLLF-
----QVLSVLLSLAGDVLVS--MYREVCSIRFLFTAVSLLSLFLAA----------IWLG
LLYLVSPLENPTPR-R---------PPPTSS--------EY----HERVRSQGQQLQQLQ
AELDK-------------LH-KEVSTVRA--------------------------ANSE-
-----------------------------RVAKLVFQ-RLNEDFVRKPDYALS-------
-----------------SV--GASIDL--QKTSHDYADRNTAYFWNRFSFWNYARPPTV-
ILEPHVFPGNCWAFEGDQGQVVIQLPGRVQLSDITLQHPPPS-VEHTGGANSAPRDFAVF
G-----------------L-----QVDD--ETEVFLGKFTF-DVEKSEIQ--TFHL--QN
DP--PAA------FPKVKIQ-------ILSNWGHPRFTCLYRV-RAHGVRTSEGAEGSAT
G--GPH------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------MSGRPKSRKGARVIRVHSE----EASSTSS----SDTVLSEH---
------------------------------------------------------------
G---------------------N-----PD---SNRLTGSWKII----------ISMAF-
--------------------------------------ILTFLLIG-------LRNHMWL
KETEFPQKSRPFYSVIA-------EYGSRLYNYQARRR-MP----KEQVELVKKESRTLE
NNFREILFLIEQIDVLKALL-RDMQNGLHSY---SWNPDGDP---------TEVQNHTE-
--------------------------EISNLVNYVLK-KLREDQVQMADYALK-------
-----------------SA--GASIIE--AGTSESYKNSKAKLYWHGIGFLNYEMPPDI-
ILQPDVHPGKCWAFPGSQGHALIKLAMKIIPTAVTMEHISEK-VSPSGDISSAPKEFSVY
-----------------GM-----SKQCE-GEEIFLGQFVY-NRTGATIQ--TFEL--QH
KV--PES------LLCVKLK-------ILSNWGHLKYTCLYRF-RVHGTPGDDT------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------LVRSWKII----------LTLAF-
--------------------------------------TLTFLLVG-------FRHHEWL
KETEFPQKSKQLYAIIA-------EYSSRLHHYQARFR-MP----KEQLELLKKESQTLE
NNFREILSLIEQIDVLKALL-RDMKDSSQNY---SWASAGDAL-----QEQDSPEVLDE-
--------------------------EMSNLVHYVLK-KLREDQVQMADYALK-------
-----------------SA--GASIIE--EGTSESYKNNKAKLYWHGIGFLNYEMPPDT-
ILQPDVHPGKCWAFAGSKGHILIKLARKIVPTAVTMEHISEK-VSPSGNISSAPKEFSVY
-----------------GI-----TKKCD-GEEIFLGQFAY-NKTENTVQ--TFEL--QQ
EA--PES------LLCVKLK-------ILSNWGHPKYTCLYRF-RVHGLPSEET------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MP----------------
--------------R---------------------------SSR----------NPG--
-----D-SCDQPEN-----------VAHVPRE--ARPR--RIIQRGRNICRMTEAPLSNA
--SDAFLLPV---------RINA---PGLTQCMLEC--ISWITC----------L-ACFL
RTRAHQV----------LFNTCRYKLFIHKLI--EKAGVLILCAFG-----------FWM
FSVHLPSKMDIWQEDS---------IDSPL----QSLR-MY----QEKVRHHTGEIQDLR
GHLN-------------QLI-TKLQEMEA--------------------------MSDEQ
K-----------------------------MTQKIIK-MIQGDYIEKPDFALK-------
-----------------SI--GASIDF--EQTSATYNHDKACSYWNWIRLWNYAQPPDV-
ILEPNVTPGNCWAFSGDRGQVTIRLAQKVYLSNLTLQHIPKT-ISLSGSLDTAPKDFVIY
-----------------GM---E---G-SPKEEVFLGAFQF-QP-ENIIQ--TFQL--QN
QP--PRT------FGAVKVK-------ISSNWGNPRFTCLYRV-RVHGSVTLPREQPNQS
PHPKRD------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------MDASF-
SFQPDISAGNCWAFQGSRGHVVIQLPEKIWPTAFTIWHISKA-VSPSGEVSTAPREFAVS
G-----------------V-----DED-E-GEA-LLGSFIY-DVDGEIAQ-----T--FP
VQ-----------VWQV----------LAAECQGGRPGCLQVL-GRKGLPDHPGLP---L
LCNAADS-------------CGAD-RRGGRPAFGSTFSSW--

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------MDASF-
SFQPDISAGNCWAFQGSRGHVVIRLPEKIWPTAFTLWHISKA-VSPSGEVSTAPREFAVS
G-----------------V-----DED-E-GEA-LLGSFIY-DVDGEIAQ-----T--FP
VQ-----------VWQV----------LAAECQGGRPGCLQVL-GRKGLPDHPGLP---L
LCNAADS-------------CGAD-RRGGCPAFGSTFSSW--

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MP----------------
--------------R---------------------------SSR----------SPG--
-----DPGAL-LED-----------VAHNPRP--R----R-IAQRGRNTSRMAEDTSSNM
N-D-NFLLPV---------RINA-QAPGLTQCMLGC--VSWFTC----------F-ACSL
KTQAQQF----------LFNTCRCKLLCQKLM--EKTGILLLCAFG-----------FWM
VSIHLPSKMKVWQDDS---------INGPL----QSL-RLY----QEKVRHHSGEIQDLR
GSMN-------------LLI-AKLQEMEA--------------------------MSDEQ
K-----------------------------MAQKIMK-MIHGDYIEKPDFALK-------
-----------------ST--GASIDF--EHTSATYNHEKAHSYWNWIQLWNYAQPPDV-
ILEPNVTPGNCWAFEGDRGQVTIQLAQKVYLSNLTLQHIPKT-ISLSGSLDTAPKDLVIY
-----------------GM---E---G-SPKEEVFLGAFQF-QP-ENIIQ--MFPL--QN
QP--ALA------FSAVKVK-------ISSNWGNSAFTCLYRV-RVHGSVAPPREQPHQN
PYPERD------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MP----------------
------------------------------------------RSR----------NTG--
-----D-SCALPED-----------SSHCTRP--R----R-SLQAHVLRSMSL-WSMFSA
D-D-ALLLPF---------RINT-PGLSLTQFILGY--MSWLTC----------L-ACFL
RTQVQQV----------LLNTFRCKLLCQKLM--EKIGLLVLCAFG-----------FWM
FSIHLPSKMEVWQDDS---------INGPL----QSLR-MY----QEKVRHHTGEIQDLR
GSMN-------------QLI-AKLQEMEA--------------------------MSDEQ
K-----------------------------VAQKIMK-MIQGDYIEKPDFALK-------
-----------------SI--GASIDF--EHTSATYNHNKARSYWNWIRLWNYAQPPDV-
ILEPNVTPGNCWAFAGDRGQVTIRLAQKVYLSNLTLQHIPKT-ISLSGSLDTAPKDFVIY
-----------------GM---E---S-PPREEVFLGAFQF-QP-ENTIQ--MFPL--QN
QP--PRA------FAAVKVK-------ISSNWGSPRFTCLYRV-RVHGSITPPRDSHL--
------------------------------------------

------------------------------------------------------------
---------------------------------------------------MSRRSQRLT
---RYSQG-DDD-GSSSSGGSSVMGSQSTAFKDSPLRTLK-RKSS--NMKRLSPAPQLGP
SSDAHTSYYSES--VVRESWPPPSASLKE-----------LH------------------
---------------------------------------------------PDDGLRRRR
GT---DIKSSKINGLQEN--KPFEEFLVSSSGYSSEDDYVEDSDSLHVPGLLRVRQAELV
PSFPAGYS-ETDQRGSGSR---LRNAVSQVA--SFFW-----------------------
------MVVTSPGRLFGLLYWWIG-TWYRLT--TASLLEVFXXXXR--FS----SLKTF-
LWFLLLLLLLTGLTYGA--WHFYPYGLQTFHPALVSWWAAKG----SSEQHEVWGSRDSS
PH---FQAEQRILSRV--HSLERRLEDLAAEFSSSWQKEALRLER-LELRQGAGGQGG--
------SGGLSHED-----------TLALLEG--L--VSRR------E-AALKEDFRRDT
A---------------------A-----RIQXXXXX---XXXXXXXXXXXXXXKIVQASQ
ESEARLQQLKSEWQXX-XXXXXXXXXXXXXXX--XXXXXX---XXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXX-------XXXXXXXXXXXXXX-XX----X----XXXXXX-XXX
XXXXX-----XXXXXXXXXX-XXXXXXXX-----XXXXXXX-XXXXXXXXXXXXXXXXXX
-----------------------XX----XXXXXXXX-XXXXXXXXXXXXXXX-------
-----------------XX--XXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXX-XXXX-
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXX
X-----------------X-----XXXXX-XXXXXXXXXXXXXXXXXXXX--XXXX--XD
PQ--MAT------YQVVELR-------ILTNWGHPEYTCIYRF-RVHGEPAH--------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------MRRSSRP--------------
------------GSASSSRKH---TPNFFSENSSMSIT--SEDSK--GL-RSAGPGPGEP
EGR--RARGPSCGEPALSAGVPGGTTWAGSSQQKPAPRSHNWQ----TAC-GAA-TVR-G
GASEPTGSPV--VSEE---PLDLLPTLDLRQEMPPP-RVFKSF-----------LSLLF-
----QGLSVLLSLAGDVLVS--MYREVCSIRFLFTAVSLLSLFLSA----------FWLG
LLYLVSPLENPTPR-R---------PPPTSS--------EY----HERVRSQGQQLQQLQ
AELDK-------------LH-KEVSTVRA--------------------------ANSE-
-----------------------------RVAKLVFQ-RLNEDFVRKPDYALS-------
-----------------SV--GASIDL--QKTSHDYADRNTAYFWNRFSFWNYARPPTV-
ILEPHVFPGNCWAFEGDQGQVVIQLPGRVQLSDITLQHPPPS-VEHTGGANSSPRDFAVF
G-----------------L-----QVDD--ETEVSLGKFTF-DVEKSEIQ--TFHL--QN
DP--PAA------FPKVKIQ-------ILSNWGHPRFTCLYRV-RAHGVQTSEGAEGSAQ
G--PH-------------------------------------

------------------------------------------------------------
---------------------------------------------------MSRRSQRLT
---RYS-QVDDDGGSSSSGGSSVAGSQSTLFKDSPLRTLK-RKSS--NMKRLSPAPQLGP
SSDAHTSYYSES--MVRESYIGSPQAVSL------ARSALLD-DHLHNEPYWG-------
---------------------------------------------------EDLHVRRRR
GT--GGTDSSKANGLA-ES-KATEDFLGSSSGYSSEDDF---------------------
----AGYA-DMEQQSSGSK---LGSVVSQAG--SFAW-----------------------
------AVVTFPGRLFGLLYWWLGTTWYRLT-TAASLLDVFVLTRR--FS----SLKTF-
LWFLLLLLLLTGLTYGA--WYFYPFGLQTLHPAVVSWWAASV----SRKQPEVWDSRDSA
PH---LQAEQRILSRV--HSLERRLEALAAELSSNWQRESIRLER-LELRQGASGQGG--
------GSGLSHED-----------TLALLEG--L--VSRR------E-AALKEDFRRDT
A---------------------M-----RIQEEVAT---VRAEHHQDSEDLFKKIVQASQ
ESEARIQQLKSEW----Q--RMTQEAIRENSA--QELGRLEAQLAGLRQELAALTLKQSS
LEDEVGLLPQKIKAMRE-------EVESQFPAWVGHFL-LQ----G---GGARAGL-LQR
EEVQA-----QLQELESKIL-AHVTEMQG-----KSAQEAAALLGRTLQKEGVVGVTEEQ
-----------------------VH----RIVKQALQ-RYSEDRIGMVDYALE-------
-----------------SG--GASVIS--TRCSETYETKTALLSLFGIPLWYHSQSPRV-
ILQPDVHPGNCWAFQGPQGFAVVRLSARIRPTAVTLEHVPKA-LSPNSTISSAPKDFSIF
G-----------------F-----DEDLQ-QEGTLLGTFTYDQD-GEPIQ--TFYF--QT
PK--MAA------YQVVELR-------ILTNWGHPEYTCIYRF-RVHGEPSH--------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MP----------------
--------------R---------------------------TSR----------SPR--
-----D-LGDPLDD-----------VAHLCRD--PRPRSPRAVQRGRNPCRMTEESSRNM
--NDPFLFPL---------RLNG-PSPGLIQFVMGC--MSWITC----------L-ACIL
RTQVHQV----------LFNTFRCKLLFQKLM--EKTGVLVLFLFG-----------FWV
FMMHLPSKVEVWQDDS---------INTPL----QTVR-MY----QEKVRHHTGEIQVLR
GTIN-------------QLV-AKLQEMEA--------------------------MSDEQ
K-----------------------------MAQKIMK-MIQGDYIEKPDFALK-------
-----------------SI--GASIDF--EQTSATYNYNKARSYWNWIRLWNYAQPPDV-
ILEPNVTPGNCWAFSGDRGQVTIRLAQKVYLSNLTLQHIPKT-ISLSGSLDTAPKDFVIY
-----------------GM---E---G-SPREEVFLGAFQF-QP-ENIIQ--TFQL--QN
QP--TRT------FGAVKVK-------ISSNWGNPRFTCLYRV-RVHGSVTPPREQPN--
------------------------------------------

------------------------------------------------------------
----------------------------------------------PPAAAMSRRSQRLV
TS-RYYPGDDDAAASSSSSSASLLGGTQLPFKETTGRTI-RRKSS--STK------RLSP
APSTQTSYYSES--MMSESYLGGSRGLAA------LGSSML-DDDLDSGTYWG-------
---------------------------------------------------GELSSRRRR
GT-G-DTESSKINGVLES---KTYDTYTSSSGYSSEDDYAGHC-----------------
---------YSGQSSSGSG---LRTAASRVG--SFLW-----------------------
------QVFTSPVRFLGWLFSGLAGAWRRLT-GTASHLDRVPFSRR--YP----RLKRS-
LLLLLLLLLLAAAAYGA--WYFYPYGLSTLSLPSFPWWGAGKLSSSS----DVPGAGDLT
TLDQG---GHRLQARL--QSLEKRFEALEAELS-----------R-WELRRGAAAVT---
-----AGGEPPPGD-----------ILAQLEG--L--VSRR------D-AGLKEHLRADV
A---------------------N-----HLQGELDA---LRAQVQRDLDGRLGKMAQASR
EMEARLLELNSEW----Q--SSAQESLRGTFR--QELGKLEQEVAVLRRELASLKSDQEV
MGKHVEGILEQLKTVRA-------DVEAQFPLWISRFL-SQ----SQHD-GAAAFI-LQR
EDLQA-----ELQALEHKIL-AKVLEDRR-----LSARDAQAGIGVALRQGGTAGVTEEQ
-----------------------VH----LIVGQALK-RYSEDRVGMVDYALE-------
-----------------S--AGASVIN--TRCSETYETRTALLSLFGIPLWYHSQSPRV-
ILQPDVNPGNCWAFRGSQGFAVIRLSGIIRPMAVTLEHIPKA-LSPQGTIPSAPKDFAVY
G-----------------L-----KEEGE-EEGLLLGQFTYDHN-GDPIQ--TFYL--EG
DS--VGT------YQLVELR-------VLSNWGHPEYTCIYRF-RVHGEPAH--------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------M--ERTSKSYGGNRWL----SP-FFSSAKPPET-
ILQPDISAGNCWAFQGSRGHVVIRLPEKIWPTAFTIWHISKA-VSPSGEVSTAPREFVVS
G-----------------V-----DED-E-GEA-LLGSFIY-DVDGEIAQ--TFQV--QE
EP--RKA------FRQIKLE-------VRSNWGNKEYTCLYRA-DVHGNPEKA-------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MP----------------
--------------R---------------------------SSR----------SPE--
-----D-SCDQPEN-----------VAHVSRE--VRPR--RIIQRGRNICRMTEAPLSNA
--SDAFLLPV---------RINA---PGLTQCMLEC--VSWITC----------L-ACFL
RTRAHRV----------LFNTCRYKLFIHKLI--EKAGVLILCAFG-----------FWM
FSVHLPSKMDIWQEDS---------IDSPL----QSLR-MY----QEKVRHHTGEIQDLR
GHLN-------------QLI-AKLQEMEA--------------------------MSDEQ
K-----------------------------MTQKIIK-MIQGDYIEKPDFALK-------
-----------------SI--GASIDF--EQTSATYNHDKACSYWNWIRLWNYAQPPDV-
ILEPNVTPGNCWAFSGDRGQVTIRLAQKVYLSNLTLQHIPKT-ISLSGSLDTAPKDFVIY
-----------------GV---E---G-SPKEEVFLGAFQF-QP-ENIIQ--TFQL--QN
QP--PRT------FGAVKVK-------ISSNWGNPRFTCLYRV-RVHGSVTLPREQPN--
------------------------------------------

------------------------------------------------------------
---------------------------------------------------MSRRSQRLT
---RYS-QGDDDGGSSSSGGSSVAGSQSTLFKDSPLRTLK-KKSS--NMKRMSPAPQLGP
SSDTHTSYYSES--VIQESYIGSPRASSL------ARSALLD-DHLRSEPYWD-------
---------------------------------------------------EDLRVRRRR
GT--GGTESSKANGLV-ES-KATEDFLGSSSGYSSEDDF---------------------
----AGYS-DMDQHSSGSS---LGSVVSRAG--SFVW-----------------------
------TVITFPGRLFRLLYWWVGTTWYRLT-TAASLLDVFVLTRR--FS----MLRTF-
LWFLLLLLLLTGLTYGA--WYFYPFGLQTSHPAVVSWWAARD----SRRQPEVWDSRDTT
PH---FQGEQHILSRV--HSLERRLEALAAEFSSSWQKQSIRLER-LELWQGSTGHRG--
------GGGLNHED-----------TLALLEG--L--VSRR------E-AALKEDFLRDT
A---------------------T-----RIQEELAT---VRAEHHHDSEDLFKKIVQASQ
ESEARLQQLKMTQ----EN-SVLWENIRKNSV--EELGRMEAQLTGLRQELAALSLKQSE
VEDEVGLLPQKIQAVRE-------DVESQFPAWVGHFL-LH----G---GGTRAGL-LQR
EEVQA-----QLQELESKIL-THVTEMQG-----KSTQEAAALLGQTLQKEGMVGVTEEQ
-----------------------VH----QIVKQALQ-RYSEDRIGMVDYALE-------
-----------------SG--GASVIS--TRCSEPYETKTALLSLFGIPLWYHSQSPRV-
ILQPDVHPGNCWAFQGPQGFAVVRLSARIRPTAVTLEHVPKA-LSPNSTISSAPKDFSIF
G-----------------F-----DEDLQ-QEGTLLGTFTYNQD-GEPIQ--TFHF--QT
PK--MAE------YQVVELR-------ILTNWGHPEYTCIYRF-RVHGEPAH--------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MP----------------
--------------R---------------------------SSR----------SPG--
-----DPGAL-LED-----------VANNRRP--R----R-IAQRGQNTSRMAEDPSSNM
N-D-AFLLPV---------RTNA-QGLGLTQCMPGY--VSWVTC----------L-AFFL
RTRAQRV----------LFDKCRWKLLCQKLL--EKTGMVFLCAFG-----------FWM
FSIHIPSKMTVWQDSS---------ITTTM----QSLR-LY----QEKVRCLSKEIQDLR
GHVN-------------LLV-AKLQEMEA--------------------------MSNEQ
K-----------------------------MAHKIMK-MIQGDYIEKPDFALK-------
-----------------ST--GASVDF--EHTSATYNHNKAHSYWNWIKLWNYAQPPDV-
ILEPNVTPGNCWAFEGDHGHVTIRLAQKIYPSSLTLQHIPKT-ISLSGSLDTALKDFVVY
-----------------GM---E---S-SPREEVFLGAFQF-QP-ENTIQ--MFPL--QN
QP--ARA------FSAVKVK-------ITSNWGNPGFTCLYRV-RVHGSVAPPKEQPHEN
PYPEKD------------------------------------

------------------------------------------------------------
---------------------------------------------------MSRRSQRLT
---RYS-QGDDDGGSSSSGGSSVMGSQSTLFKDSPLRTLK-RKSS--SLKRLSPSP--AP
SSDTHTSYYSES--LIKESRP--------------PRSSILD-DPLHSDPYWS-------
---------------------------------------------------EDLRGRRRR
GT--GGTESSRINGLM-ES-KRSEDFLGSSSGYSSEDDYVEGSHR----GLPKPMAIELA
SSLLAGYTAELDQQSSGSW---LRNAISRTG--SFIW-----------------------
------MVVTSPGRLFELLYWWVGTTWYRLT-TAASLLDVFVLT--RRVS----SLRTF-
LWFLLLLLLLTCLTYGA--WYFYPYGLQTFQPAVASWWAAKD----SSRQHEVWEPRESS
PH---FQAEQRILSRV--HSLERRLEALAAEFSSHWQKEALRLER-LELRQGSASEG---
-----GGGGLSHED-----------TLALLEG--L--VNRR------E-AALKEDFRKDT
A---------------------A-----RIQEELGA---LRAEHQQDAEDLFKKITQVSQ
ESEARLQQLKSEW----Q--RMTQESLQENSV--KELGWLEGQLAGLRQELAALAVKQGS
VEDRMDQLPQQIQTVRA-------DVESQFPAWITEFL-LQ----G---GGSRAGL-LQR
EETDA-----RLQELESRVL-AHVAEAQG-----RSAKEAAASLGLMLQREGVIGVTEEQ
-----------------------VH----RIVNQALK-RYSEDRIGMVDYALE-------
-----------------SG--GASVIS--TRCSETYETKTALLSLFGIPLWYHSQSPRV-
ILQPDVHPGNCWAFQGPQGFAVVRLSARIRPTAVTLEHVPKS-LSPNSTISSAPKDFAIF
G-----------------F-----DEDLQ-QEGTLLGKFTYDQD-GEPIQ--TFYF--QD
PA--LAT------YQVVELR-------VLTNWGHPEYT----------------------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------V--ERTSKSYGGNRWL----SP-FFSSAKPPET-
ILQPDISAGNCWAFQGSRGHVVIRLPEKIWPTAFTIWHISKA-VSPSGEVSTAPREFVVS
G-----------------V-----DED-E-GEA-LLGSFIY-DVDGEIAQ--TFQV--QE
EP--RKA------FRQIKLE-------VRSNWGNKEYTCLYRA-DVHGNPEKA-------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----MTPGNCWAFSGDRGQVVIRLARKIFLTNVTIQHIPKT-ISLSGSLDTAPKDFVVY
VNFLAFD------TDPHGI---N---D-KIKEETFLGAFLF-QP-ENSIQ--MFPL--QN
SL--CKS------FNYIKLK-------ILTNWGNPHFTCLYRV-RAHGTISRPAHDHYPQ
G-----------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------WS-------SVKEMT
KRKSGLYMLLFLIFLSA-LIGAYGGTTLARVLWTEDLL-Q-------------------M
LSLQTAP-------RPMNSG-NSLTEETQ---------------GIENQRNGVSYLAEEH
---------------------GIAMKDAQDLREAACV-MPKEKCFTKCDRALK-------
-----------------SA--GVSIDL--QRSSRSAWH-----CKV-AWFLCTQNVVET-
FEQLDMSPGYCWRLKASQSQVVFNLPTKVQPTAVTVQHSVETN---LWHVSSAPRDFAVF
G-----------------L-----DEEGE--KEALLGKFTY-DVRKEVTQ--TFQL--QT
ET--PRA------FWYIKLV-------VLNNWGNAGHTCIYRV-QVHGKRAGTNDIGQGH
V-----------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------LQNSEKL-----------KRIEF-
--------------------------------------------SSIPR-----------
----------QLYELSA-------YFGSKFYNYQARVR-MT----KSKMELLKKGSQYLE
ENAKEIMSLTKQINLMKVLL-KDIRDQMD-----NYVMNA---------EADVTAELDES
---------------------E-XX---XXXXXXXXX-XXXXXXXXXXXXXXX-------
-----------------XX--XASIVE--AGTSESYRNDKAKLYWHGIGFLSYEMPPDI-
ILQPDVHPGNCWAFPGSEGHTVIKLARKIIPTAVTMEHISER-ISPSGSTASAPRDFSVY
X-----------------X-----XXXXX-XXX-XXXXXXXXXXXXXXXX--XXXX--XN
ED--VGS------LSYVKLK-------ILNNWGHSKYTCLYRF-RVHGKPE---------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MNE----------SPE--
-----D-------------------S--------------YLI------TRTSEQSTSEE
D--SPQIVTA--------------IIPSSCRNLLSS--LIQIIC----------F-ISNL
RNTVHKLHLFPKYIGRTQTGEATLKNLLHKLV--EKLSVVFFCVFA-----------FWC
IIIYLPTKLDTDREES--------GFDSPLSLYIHSSKRLY----QEKVRKHAEEIQALH
NLMK-------------QIS-AKIQEVKV--------------------------MSNED
L-----------------------------VAQNIMK-KIQGDYIEKPDFALK-------
-----------------SI--GGTIDF--EHTSATYSCDKARSYWSWLRLWNYAHPPDV-
ILEPNVTPGNCWAFRGDRGQVVIRLARKIFLTNITIQHIPKT-ISLSGNLDTAPKDFVVY
-----------------GI---S---D-QSREETFLGAFMF-QP-ENAIQ--MFPL--QN
TL--SRP------FNCIKLK-------ILTNWGNPHFTCIYRV-RAHGTVTPSASDY---
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------MRRSHRP--------------
------------GSAASSHNH---APDFYSENSNSSHSVTSGDSN--GR-RSPGPELEQP
EGR--RARGSSCGEPALSPGVPGGDTRAGSSRPKPAPRSHNGQ----TACGAAT-VRG-G
S-SEPCGSS--AVLEE---QLNLIPSLDLRQEMPPV-RVSKSF-----------LNLLF-
----QVLSVLLSVAGDALVS--VYREVCSIRFLLTAVTLLSVFLAA----------LWWG
LLYLVPALENEPKE------------MLTLS--------QY----HQRVYSQGQQLQQLQ
TELNK-------------LH-KEVSSVRA--------------------------AHSE-
-----------------------------RVAKLVFQ-RLNEDFVRKPDYALS-------
-----------------SV--GASIDL--EKTSSDYEDTNTVYFWNRLSFWNYARPPSV-
ILEPDVFPGNCWAFEGDQGQVVIRLPGHVQLSDVTLQHPPPT-VAHTGGASSAPRDFAVF
G-----------------L-----QADD--ETEVFLGKFIF-DVQKSEIQ--TFHL--QN
DP--PSA------FPKVKIQ-------ILSNWGHPRFTCLYRV-RAHGVRISEWAEDNAT
G--VAGG-----------------------PH----------

---------------------------------------LISPP--------PRVTWGQP
----------------------------QASLVFLFSLPKPSGKGSISHLIMSRRSQRLT
---RYS-QGDDDGN-SSSGGSSVTGSHNSLFKDSPLRTLK-RKSS--NMKRLSPAPQLGP
SSDAHTSYYSES--MVQESCIGNPRAALL------ARNALLH-D-LHSDSYWS-------
---------------------------------------------------EDLRVRRRR
GT--GGTESSKVNGLT-EG-KVSEDFLGSSSGYSSEDDFMGYS-----------------
---------DTDQQNPGSR---LRSAVSRLG--SFFW-----------------------
------MVVTFPGRLFGLLYWWIGTTWYRLT-TAASLLDVFVLTRR--FS----SLKTF-
LWFLLLLLFLTCLTYGA--WYFYPYGLQTFHPAVVSWWAAKD----SRTQQEGWDSRDS-
PH---FQAEQRVLSRV--HSLERRLEALAAEFSSNWQKEALRLER-LELRQGAAGQGG--
------GGDLSHED-----------TLALLEG--L--VSRR------E-AALKDDLRRDT
T---------------------A-----RIQEELAA---LRAEHQQDSEDLFKKIVQASQ
ESEARIHQLKSEW----Q--RMTQESFQEHFV--KELGRLEDQLAGLRQELAALTLKQSS
VADEVGLLPQQIQAVRD-------DVESQFPAWINQFL-LR----G---GGTRTGF-LQK
EEMQA-----QLQELENRIL-AHMAEMQG-----KSATEAAASLGLTLQKEGVIGVTEEQ
-----------------------VH----RIVKQALQ-RYSEDRIGMVDYALE-------
-----------------SG--GASVIS--TRCSETYETKTALLSLFGIPLWYHSQSPRV-
ILQPDVHPGNCWAFQGPQGFAVVRLSARIRLTAVTLEHVPKA-LSPNSTISSAPKDFAIF
G-----------------F-----DEDLQ-QEGTLLGKFTYDQD-GEPIQ--TFYF--QP
PK--MAT------YQVVELR-------ILTNWGHPEYTCIYRF-RVHGEPAH--------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MP----------------
--------------R---------------------------SSR----------SPG--
-----DPGCP-PEN-----------VAHGARP--R----R-AAQRGRNACRIIEDSSPNL
N-D-AFLLPV---------RINA-PALGLTQCMLGC--MSWVTF----------V-ACFL
RTQAQQV----------LFNTCRCKLLCQKVM--EKTGVLVLCAFG-----------FWM
FSIHLPSKVEVWQDDS---------INSPL----QSLR-MY----QEKVRHHTGEIQDLR
GSMN-------------LLI-AKLQKMEA--------------------------MSDEQ
K-----------------------------MAQKIMK-MIQGDYIEKPDFALK-------
-----------------SI--GASIDF--EHTSATYNHDKARSYWNWIRLWNYAQPPDV-
ILEPNMTPGNCWAFEGDRGQVTIRLAQKVYLSNLTLQHIPKT-ISLSGSLDTAPKDFVIY
-----------------GM---E---S-SPKEEVFLGAFQF-QP-ENTIQ--MFPL--QN
QP--ARA------FSAVKVK-------VSSNWGNPRFTCLYRV-RVHGSVVPPKEQSD-T
PLPERD------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------MSGRTKARRADRFFRGHSE----EASSSAI----GNVLLSEH---
------------------------------------------------------------
E---------------------N-----PD---ANRGIQSRKIV----------LSIIL-
--------------------------------------SLTFLVVG-------LRSHQWL
KEIEFPQKSRQVYAILA-------EYGSRIYNYQAKLR-MP----KEQLELLKKESQTLE
NNFRDILFLIEQIDVLKALL-RDVKDGAYNQ---SWSTHGDPA-----RHQDST----E-
--------------------------EMTNLVNYVLK-KLREDQVQMADYALK-------
-----------------SA--GASIIE--AGTSESYKNHKAKLYWHGIGFLNYEMPPDI-
ILQPDVYPGKCWAFPGSQGHTLIKLARKIIPTAVTMEHISEK-VSPSGNISSAPKEFSVY
-----------------GI-----MKKCE-GEETFLGQFIY-NKTGTTVQ--TFKL--QH
AV--SES------LLCVKLK-------ILSNWGHPEYTCLYRF-RVHGTPSVHI------
------------------------------------------

MGCGLSALTDRHTYTQSATRAPPGPTRAARAFAGRIVRLPARPPARVVALRVPARPWSGR
RLAQRGAPPAGSPGGKRARPGGGRASDAPGPARSLRGSKVSSGEESTSHRAMSRRSQRLT
---RYS-QGDDDGGSSSSGGSSVAGSQSTLFKDSPLRTLK-RKSS--NMKRPSPEPQLGL
SSDPHTSYYSES--LVRESYIGSPRAAFL------ARSA-LE-E-LHSDPDWG-------
---------------------------------------------------DHLRVRKRR
GT--GGSESSRASGLV-VG-KAAEDFLGSSSGYSSEDDYV--------------------
-----GYS-DADLQSSGSR---LQSVVSRVG--SLLW-----------------------
------MVATSPGRLFRLLYWWAGTTWYRLT-TAASLLDVFVLTRR--FS----SLKTF-
LWFLLLLLLLTCLTYGA--WYFYPYGLQTFHPALVSWWTAKD----SRREHEGWESRDSS
PH---FQAEQHVLSRV--HSLERRLEALAAEFSSNWQKEAMRLER-LELQQGTPAQGG--
------SGGLSHED-----------TLALLEG--L--VSRR------E-AALREDFRRET
A---------------------A-----RIQEELAA---LRAEHQQDSEDLFKKIVRASQ
ESEAHIQQLKSEW----Q--SMTQEAFRESSV--KELRRLEDQLAGLQQELAALVQKQSS
VADEVHLLPQQIQATRD-------DVESQFPAWISEFL-AR----G---GGGRVGL-LQR
EEMQA-----QLRDLENKIL-THIAEMQG-----KSAREAAASLGLTLQKEGVIGVTEEQ
-----------------------VH----RIVKQALQ-RYSEDRIGLADYALE-------
-----------------SG--GASVIS--TRCSETYETKTALLSLFGIPLWYHSQSPRV-
ILQPDVYPGNCWAFQGPQGFAVVRLSARIRPTAVTLEHVPKA-LSPNSTISSAPKDFAIF
G-----------------F-----DEDLQ-QEGTLLGKFTYDQD-GEPIQ--TFHF--QA
PM--MAT------YQVVELR-------ILTNWGHPEYTCIYRF-RVHG------EPTH--
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------MSGRPNSRGSSRLFRAPSE----DASSGSS----GSAVLPQQ---
------------------------------------------------------------
E---------------------N-----PN---ASGLTRSWKAV----------MGMVF-
--------------------------------------ILTLLLLG-------FINHMKL
KEKAFPQKSRQIYAVIA-------EYGSRLYNYQARLR-MP----KEQLELLKKESQTLE
NNFREILFLIEQIDVLKALL-RDMQDGLHNY---SWNADIDPA-----EGWNHTEVIDE-
--------------------------EMSNLVNYIL--KLREDQVQMADYALK-------
-----------------SA--GASVVE--AGTSESYKNNKAKLYWHGIGFLNYEMPPDI-
ILQPDVHPGKCWAFPGSQGHALIKLARKIIPTAVTMEHISEK-VSPSGNISSAPKEFSVY
-----------------GV-----LKQCE-GEEIFLGQFVY-NKTGTTVQ--TFAL--QH
EV--PEF------LLCVKLK-------ILSNWGHPNYTCLYRF-RVHGTPKDDS------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------MRRSSRP--------------
------------GSAASSRKH---TPDFFSENSSMSIT--SEDSK--GL-RSAGPGPGEP
EGR--RARGPSCGEPALSAGVPGGTTWAGSSQQKPAPRSHNWQ----TAC-GAA-TVR-G
GASEPTGSPV--VSEE---PLDLLPTLDMRQEMPPP-RVFKSF-----------LSLLF-
----QGLSVLLSLAGDVLVS--MYREVCSIRFLFTAVSLLSLFLSA----------FWLG
LLYLVSPLENPTPR-R---------PPPTSS--------EY----HQRVRSQGQQLQQLQ
AELDK-------------LH-KEVSTVRA--------------------------ANSE-
-----------------------------RVAKLVFQ-KLNEDFVRKPDYALS-------
-----------------SV--GASIDL--QKTSHDYADRNTAYFWNRFSFWNYARPPTV-
ILEPHVFPGNCWAFEGDQGQVVIQLPGRVQLSDITLQHPPPR-VEHTGGANSAPRDFAVF
G-----------------L-----QVDD--ETEVFLGKFTF-DVEKSEIQ--TFHL--QN
DP--PAA------FPKVKIQ-------ILSNWGHPHFTCLYRV-RAHGVRTSEGAEGSAT
G--GPH------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MP----------------
--------------R---------------------------SSR----------SPG--
-----DSGCP-PED-----------AAHCARS--R----R-AAQRSRNTCRITDDSSPNL
N-D-PFLLPV---------RINT-PALGLTQCMLGC--MSWVTF----------V-ACFL
RTQAQQV----------LFNTCRCKLFCQKVM--EKTGVLVLCAFG-----------FWM
FSIHLPSRVEVWQDDS---------INSPL----QSLR-MY----QEKVRHHTGEIQDLR
GSMN-------------LLI-AKLQEMEA--------------------------MSDEQ
K-----------------------------LAQKIMK-MIQGDYIEKPDFALK-------
-----------------SI--GSSIDF--EHTSATYNHDKARSYWNWIRLWNYAQPPDV-
ILEPNVTPGNCWAFEGDRGQVTIRLAQKVYLSNLTLQHIPKT-ISLSGSLDTAPKDFVIY
-----------------GM---E---S-SPKEEVFLGAFQF-QP-ENIIQ--MFPL--QN
QP--VRA------FNSVKVK-------ISSNWGNPRFTCLYRV-RVHGTVGPPKEQSN-N
PHPERD------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------MRRSPRP--------------
------------GSAASPH-----KPNFYSDNSNSSESVISGDSS--GH-RSAGPGPREP
EGR--RAGGSSCGEPALSPGLPGGPTWAGRSRQKPASRSHKGQ----TACGAAT-VRG-G
A-SEPTESPV--VSEE---PLDLLSTLDLRQEMPPP-RVSKSF-----------LSLLF-
----QVLSVVLSLVGDALLS--VYREVFSIRFLITAVSLLSVFLAA----------LWWG
LLYLVPPLENVSREDR---------FLDGWS--------EY----HERVRSQGQQLQQLQ
AELDK-------------LH-KEVSSVRA--------------------------AHSE-
-----------------------------RVAKLVFQ-RLNEDFVRKPDYALS-------
-----------------SV--GASIDL--EKTSRDYEDTNTAYFWNRFSFWNYARPPSV-
ILEPDVFPGNCWAFEGDQGQVVIRLPGRVELSDITLQHPPPS-VAHTGGANSAPRDFAVF
G-----------------L-----QVDD--ETEVFLGKFTF-DVKKSEIQ--TFHL--QN
DP--PSA------FPKVKIQ-------ILSNWGHPRFTCLYRV-RAHGVRTSEGAGDSAM
G--ATGG-----------------------SH----------

------------------------------------------------------------
---------------------------------------------------MSRRSQRLT
---RYS-QGDDDGGSSSSGGSSVAGSQSTLFKDSPLRTLK-RKSS--NMKRLSPAPQLGP
SSDAHTSYYSES--LVRESYIGT---AFP------PRSA-LE-E-LHGDADWG-------
---------------------------------------------------EDLRVRRRR
GT--GGSESSRASGLV-GR-KATEDFLGSSSGYSSEDDYM--------------------
-----GYS-DADQQSSGSR---LRNAVSRAG--SLLW-----------------------
------MVATSPGRLFRLLYWWAGTTWYRLT-TAASLLDVFVLTRR--FS----SLKTF-
LWFLLPLLLLTCLTYGA--WYFYPYGLQTFHPALVSWWAAKD----SRRQDEGWESRDS-
SH---FQAEQRVMSRV--HSLERRLEALAAEFSSNWQKEAMRLER-LELRQGAPGQGG--
------GGGLSHED-----------TLALLEG--L--VSRR------E-AALKEDFRREA
A---------------------A-----RIQEELSA---LRAEHQQDSEDLFKKIVRASQ
ESEARIQQLKSEW----Q--SMTQEFFRESSV--KELRRLEDQLAGLQQELAALALKQSL
VADEVGLLPQQIQAVRD-------DVESQFPAWISQFL-AR----G---GGGRMGL-LQR
EEMQA-----QLRELESKIL-THVAEMQG-----KSAREAAASLGVTLQKEGVIGVTEEQ
-----------------------VH----RIVKQALQ-RYSEDRIGLADYALE-------
-----------------SG--GASVIS--TRCSETYETKTALLSLFGIPLWYHSQSPRV-
ILQPDVHPGNCWAFQGPQGFAVVRLSARIRPTAVTLEHVPKA-LSPNSTISSAPKDFAIF
G-----------------F-----DEDLQ-QEGTLLGKFTYDQD-GEPIQ--TFHV--QA
PS--MAT------YQVVELR-------ILTNWGHPEYTCIYRF-R------VHGEPAH--
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------MRRSPRP--------------
------------GSAASPHKS---TPNCYSDNSNSSVSVTSGESS--GH-RSAGLGPGEP
EGR--RARGSSCGEPALSAGVPG-TARAGSSRQKPAPRSHTGR----TACGAAN-REG-R
GLGSPLRTPV--LIFEPLAHVGVSSSFP-ELDPTPL-RLSLFL-----------SHLLF-
----QVLSVLLSLVGDMLVS--VYREVCSIRFLLTAVSLLSLFLAA----------LWWG
LLYLIPLAENEPKE------------MLTLS--------EY----HERVRSQGQQLQQLQ
AELDK-------------LY-KEVSSVRA--------------------------ANSE-
-----------------------------RVAKLVFQ-RLNEDFVRKPDYALS-------
-----------------SV--GASIDL--EKTSHDYGDANTAYFWNRFSFWNYARPPTV-
ILEPDVFPGNCWAFEGDQGQVVIRLPSRVQLSDITLQHPPPS-VAHTSGANSAPRDFAVY
G-----------------L-----QVDD--ETEVFLGKFTF-DVEKSEIQ--TFHL--QN
DP--PAA------FPKVKIQ-------ILSNWGHPRFTCLYRV-RAHGMRTSEGAGESAT
G--GPH------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------EY----HERVHSQGLQLQQLQ
AELDK-------------LH-TDVSSIRA--------------------------ANSE-
-----------------------------RVAQLVFQ-RLNEDFVQKPDYALS-------
-----------------SV--GASIDL--DKTSHDYEDRDTAYFWNRFSFWNYAKPPTV-
ILEPDVFPGNCWAFQGAKGQVVIRLPGRVQLSDITLQHPPPS-VAHIGGASSAPKDFAVY
G-----------------L-----QGDD--KTEILLGKFTF-DVEKSEIQ--TFHL--KN
EP--PLA------FPKVKIQ-------ILSNWGHPRFTCLYRV-RAHGLRSHDMQREDSR
TKGEPVTIPH--------------------------------

-------------------------------------------------LASSTSA----
--------------------GRGEEEEPIWA--SG-AFRLSSGGRSPSYLVMSRRSQRLT
---RYS-QGDDDGGSS-SGGSSVMGSQSTLFKDSPLRTLK-RKSS--NMKRLSPAPQLGP
SSDAHTSYYSES--VVRESYFGSPRAASL------ARSSILD-DHLHGDPYWS-------
---------------------------------------------------EDLRVRRRR
GT--GGTESSKLNGLA-ED-KSSEDFLGSSSGYSSEDDFA--------------------
-----GYS-ETDHRSSGSR---LRNAVSWAA--SCFW-----------------------
------MVVTSPGRLFGLLYWWVGTTWYRLT-TAASLLDVFVLT--RRFS----SVKTF-
LWFLLLLLLMTGLTYGA--WYFYPYGLQTFHPALVSWWAAKG----SSRQHDVWESRDA-
SH---FQTEQRILSRI--HSLERRLEALAAEFSSNWQKEAMRLER-LELRQGATGGG---
-----GHVGLSQED-----------TLALLEG--L--VSRR------E-AALKEDFRRDT
A---------------------A-----RIQEELVT---LRAEHQQDLEDLFKKIVQASQ
ESEARLQQLKSEW----Q--RMTQESFRENSM--KELGRLEGQLTGLRQELAALSLKQSS
VADQVGLLPQQLQAVRD-------DVESQFPAWVSQFL-LR----G---GGTRTGL-LQR
EEMQA-----QLQELENKIL-AHVAEMQG-----KSAREAAASLGLTLQKEGVIGVTEEQ
-----------------------VQ----RIVNQALK-RYSEDRIGMVDYALE-------
-----------------SGDLGASVIS--TRCSETYETKTALLSLFGIPLWYHSQSPRV-
ILQPDVHPGNCWAFQGPQGFAVVRLSARIRPTAVTLEHVPKS-LSPNSTISSAPKDFSIF
G-----------------F-----DEDLQ-QEGTLLGQFTYDQD-GEPIQ--TFYF--QD
TK--MAT------YQVVELR-------ILTNWGHPEYTCIYRF-RVHGEPTY--------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MP----------------
--------------R---------------------------SSR----------SPG--
-----DPGAL-LED-----------VAHNPRP--R----R-IAQRGRNTSRMAEDTSPNM
N-D-NILLPV---------RNND-QALGLTQCVLGC--VSWFTC----------F-ACSL
RTQAQQV----------LFNTCRCKLLCQKLM--EKTGILLLCAFG-----------FWM
FSIHLPSKMKVWQDDS---------INGPL----QSL-RLY----QEKVRHHSGEIQDLR
GSMN-------------QLI-AKLQEMEA--------------------------MSDEQ
K-----------------------------MAQKIMK-MIHGDYIEKPDFALK-------
-----------------SI--GASIDF--EHTSATYNHEKAHSYWNWIQLWNYAQPPDV-
ILEPNVTPGNCWAFEGDRGQVTIQLAQKVYLSNVTLQHIPKT-ISLSGSLDTAPKDFVIY
-----------------GM---E---G-SPKEEVFLGAFQF-QP-ENIIQ--MFPL--QN
QQ--ARA------FGAVKVK-------ISSNWGNPGFTCLYRV-RVHGSVAPPREQPHQN
PYPERD------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------MDVSF-
SLLPDISPGSCWAFQGSQGHVVIRLPEKIQPRAFTIWHISRA-VSPCGEVSSAPEEFAVS
V-----------------S-----LCL-----------LL--LLEGPRAR--GRAL--PE
MS-----------FWW--------------------------------------------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------MRRSPRP--------------
------------GSAASPHKH---TPNFYSDNSNSSVSVTSGDSC--GH-RSAGPGPGEP
EGR--RARGSSCGEPALSAGVPGGTTWAGSSRLKPAPRSHNAQ----TACGAAT-VRG-G
A-SEPAGPPI--VSEE---QLDLLSTLDLRQEMPPP-RVSKSF-----------LSLLF-
----QVLSVLLTLVGDVLVS--VYREVCSIRFLLTAVSLLSLFLAG----------LWLG
LLYLAPPLENSQ--------------PLACR--------EY----HAQVHSQGQQLQQLQ
AELVK-------------LH-KEVSNVRA--------------------------ANSE-
-----------------------------RVAKLVFQ-RLNEDFVRKPDYALS-------
-----------------SV--GASIDL--EKTSHDYEDMDTAYFWNRFSFWNYARPPTV-
ILEPDVFPGNCWAFEGDKGQVVIRLPGRVQLSDITLQHPPPS-VAHTRGANSAPRDFAVY
G-----------------L-----QVDD--ETEVFLGKFTF-DVEKSEIQ--TFHL--QN
DP--PAA------FPKVKIQ-------ILSNWGHPRFTCLYRV-RAHGIRTSEGAGDNAR
G--GPY------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MP----------------
--------------R---------------------------SSR----------IPG--
-----D-PFVLPEH-----------MAYNTRP--R-----SPLHSRAA-M----------
------SLHN---------GTH--------CPPVST--AAWFNY----------L-ACFL
RTQAQQV----------LFNTCRCKMICHKFM--EKTGVLVLCALG-----------FWV
FSMHIPSKMEVWQDDS---------INSPL----QSLR-LY----QEKVRHHTGEIQDLR
GSVN-------------QLM-AKLKEMEA--------------------------MSDEQ
K-----------------------------LAQKIMK-MIHGDYIEKPDFALK-------
-----------------SI--GATIDF--EHTSATYHHDKARSYWNWIRLWNYAQPPDV-
ILEPNMTPGNCWAFEGDRGQVSIQLAQKVYLSNLTLQHIPKT-ISLSGSLDTAPKDFVVY
-----------------GM---E---S-SPGEEVFLGAFQF-QP-ENIIQ--MFEL--QN
QQ--LQA------FGAVKVK-------ISSNWGNPRFTCLYRV-RVHGSVSPPPRALP--
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------WS-------SVKEMT
KRKSGLYMLLFLIFLSA-LIGACCGVSLARIQWTKEFL-Q-------------------M
LSLQTAP-------RPMNSG-NLLTEETQ---------------GIENQRNGVSYLAEEH
---------------------GIAMKDAQDLREAACV-MPKEKCFTKCDRALK-------
-----------------SA--GVSIDL--QRSSRSAWH-----CRV-AWLLCTQNVVDT-
FEQLDMSPGYCWRLKESQSQVVFNLPTKVQPTAVTVQHSVETN---LWHVSSAPRDFAVF
G-----------------L-----DEEGE--KEALLGKFTY-DVRKEVTQ--TFQL--QT
ET--PRA------FWHIKLV-------VLNNWGNAGHTCIYRV-QVHGKRAGTNDIGQGH
V-----------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------MLFNTCKVF----------YRCFL-
--------------------------------------ISSLMRVW-------LQNHQWF
KETEFPQKPRQLYTLIA-------EYGSRLYNYQARLR-MP----KEQLELLKKESQTLE
NNFREILILIEQIDILKALL-RDMKDGVHNH---SWPVHREAV-----QDQVTTAALDE-
--------------------------EMSNLVHYVLK-KFRGDQIQMADYALK-------
-----------------SA--GASVIE--AGTSESYKNNKAKLYWHGIGFLNYEMPPDM-
ILQPDIHPGKCWAFPGSQGHILIKLARKIIPTAVTMEHISEK-VSPSGNTSSAPKEFSVY
-----------------GI-----MKKCE-GEEMFLGQFMF-NKTETTIQ--TFEL--QN
EA--SES------LLCVKLQ-------ILSNWGHPKYTCLYRF-RVHGIPSDHT------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------MDTSWIHFHCTT----MGMSTSQ----VLNPLSHN---
------------------------------------------------------------
--------------------------------------GNASSI----------LSVFC-
--------------------------------------FLISSLTG-------FRNHVRL
KEKEFPQKSRQFFAVIA-------EYGSRLYNYQARLR-MP----KEQLELLKKESQILE
NNFREILFLMEQIDVLKALL-RDTQAGLHNY---SWNTDGDPT-----GVQDHPEVIDE-
--------------------------EMSHLVNYILK-KLREDQVQMADYALK-------
-----------------SA--GASVIE--AGTSESYKNNKAKLYWHGIGFLNYEMPPDI-
ILQPDVHPGKCWAFPGSQGHALIKLARTIIPTAVTMEHISEK-VSPQETSPPPCLLLSLQ
-----------------GI-----SKQCE-GEEIFLGQFIY-NKTGTTVQ--TFTL--QH
EV--SEF------LLCVKLK-------ILSNWGHPKYSCLYRF-RVHGTPRDDT------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------HHCFK------------------------------
RGR---VRWLTPVLPALWEAEAGGSLELGSSNHC----TPAWA----M----RK-TLP-W
FPAEPTGSPV--ISEE---PLDLLPTLDLRPEMPPS-RMFKSF-----------LSLLF-
----QVLSV-LSLAGDVLVS--MYREVCSIRFLFTAVSLLSLFLAA----------IWLG
LLYLVSPLE------------------------------NY----HERVRSQGQQLQQLQ
AELDK-------------LH-KEVSTVRT--------------------------ANSE-
-----------------------------RVAKLVFQ-RLNEDFVRKPDYALS-------
-----------------SV--GASIDL--QKTSHDYADRNTAYFWNRFSFWNYARPPTV-
ILEPHVFPGNCWAFEGDQGQVVIQLPGRVQLSDITLQHPPPS-VEHTGGANSAPRDFAVF
G-----------------L-----QVDD--ETEVFLGKFTF-DVEKSEIQ--TFHL--QN
DP--PAA------FPKVKIQ-------ILSNWGHPRFTCLYRV-RAHGVRTSEGAEGSAT
G--GPH------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------MVSLDEELAKVQRQLHVLQWRARDI-T--------------------
------------------------------------E--RALH--EALRRTELPGFTGEA
-----------------------VQ----KIIDQVLE-KLEESPFQMTNYASK-------
-----------------TS--GAAIVR--SKTSPSWIG-SGRVFWQSLPLVAYMRPPEV-
ILEPDNHPGNCWPFPGSQGHVFIKLPVAVFPTAVTINHGVPAAAYHADSISSAPKDFAVY
G-----------------L-----QAEDD-EKGTLLGEFIF-TPGQAPGQ--TFQL--KN
EH--SGF------IKYVRLQ-------VLSNWGHRDYTCVYQF-RLHGDP----------
--AHD-----------------GD-TRGKLS---A-------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------MSGRANLRR-TAFFGGRSE----EASGSAS----VHGLLSEH---
------------------------------------------------------------
E---------------------N-----PD---TQGMIQSRKII----------LSMMV-
--------------------------------------TLTFLIVG-------LLNHQWL
KQTEFPQKSRKLCALIA-------EYGSRFYNYQARLR-MP----KEQLELLKKEHQTLE
NNFREILFLNEQIDVLKALL-SDMKAGVYNY---SWNAHEYPA-----QDQDNT----E-
--------------------------EMSNLVNYVLK-RWREDQVQMADYALK-------
-----------------SA--GASIIE--AETSESYKNTKAKLYWHGIGLLNYEMPPDI-
ILQPDVYPGKCWAFPGSQGHTLIKLAKKIIPTAVTMEHISEK-VSPSGNISSAPREFSVY
-----------------GI-----MKKCE--EEIFLGQFIY-NKTGSTVQ--TFVL--QH
EV--SES------LLYVKLK-------ILSNWGHPEYTCLYRF-RVHGTPGGHT------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------SQT
-----------------------VK----RMLNKVLE-KLDEDQVQMPDYALK-------
-----------------SA--GASIIQ--SRTTRSYRHNGGKFFWLSFPMLVFVKSPEV-
ILQPSNYPGDCWPFSGNQGETLIKLAMEIIPRAVTMEHISKK-ISPTGEISSAPKDFAVY
G-----------------L-----KEEDE-EQGTFLGQFLY-NHEGDLFQ--TFQLLVQN
EL--PEF------MRYVKLK-------VLNNWGHPEYTCIYRF-RVHGDLKNA-------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------MSARLNLRRNARFSGIPSE----EAKSGTS---------------
-----------RA-------------------------------------DQQ------P
E---------------------V-----QN---LNPPRKIWKII----------TTVVL-
--------------------------------------LLILLLSG-------FYNKEWL
KETRISQNTLELYDVLA-------DYGFKLYQNQVRGR-DS----KGHQERLRMGTVDLK
NNLREILALKEQINTLKAEL-NHAMKEINNF---SLHADGDVR-----EGQGRETVSDK-
--------------------------EMSKMVNYVLK-KLREDQVEMADYALK-------
-----------------SA--GASIVE--AGTSENYKNEKAKLYWYGLGFLNYEMPPDV-
ILQPAVHPGNCWAFPGPQGHAIIKLARKVIPKAVTLEHISER-ISPSGNITSAPKDFSIY
-----------------GL-----RDECE-GEGIFLGQFMY-DKTGTAVQ--TFHL--KV
EV--SEF------LSCVKLK-------ILTNWGHPKFTCVYRF-RVHGNPESNM------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------MLTRSWKII----------LSTVF-
--------------------------------------ISTFLLVG-------LLNHQWL
KETEFPQKPRQLYTVIA-------EYGSRLYNYQARLR-MP----KEQQELLKKESQTLE
NNFREILFLIEQIDVLKALL-KDMKDGVHNH---SLPVHRDAV-----QDQATTDVLDE-
--------------------------EMSNLVHYVLK-KFRGDQIQLADYALK-------
-----------------SA--GASVIE--AGTSESYKNNKAKLYWHGIGFLNYEMPPDM-
ILQPDVHPGKCWAFPGSQGHILIKLARKIIPTAVTMEHISEK-VSPSGNISSAPKEFSVY
-----------------GV-----MKKCE-GEEIFLGQFIY-NKMEATIQ--TFEL--QN
EA--SES------LLCVKLQ-------ILSNWGHPKYTCLYRF-RVHGIPSDYT------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------MRRSSRP--------------
------------GSASSSRKH---TPNFFSENSSVSIT--SEDSN--GL-RSAGPGPGDP
EGR--GARGPSCGEPALSAGVPRGTTWAGSSRQKPAPRSHNWQ----TAC-GAA-TVR-G
GASEPTGSPA--VSEE---PLDLLPTLDLRQEMPPS-RVFKSF-----------LSLLF-
----QVLSVLLSLAGDVLVS--MYREVCSIRFLFTAVSLLSLFLAA----------IWLG
LLYLVSPLENEPN------------EMLTLS--------EY----HERVRSQGQQLQQLQ
AELDK-------------LH-KEVSTVRA--------------------------ANSE-
-----------------------------RVAKLVFQ-RLNEDFVRKPDYALS-------
-----------------SV--GASIDL--QKTSHDYADRNTAYFWNRFSFWNYARPPTV-
ILEPHVFPGNCWAFEGDQGQVVIQLPGRVQLSDITLQHPPPS-VEHTGGANSAPRDFAVF
G-----------------L-----QVDD--ETEVFLGKFTF-DVEKSEIQ--TFHL--HN
DP--PAA------FPKVKIQ-------ILSNWGHPRFTCLYRV-RAHGVRTSEGAEGSAT
G--GPH------------------------------------

------------------------------------------------------------
---------------------------------------------------MSRRSQRLT
---RYS-QGDDDGS-SSSGGSSVAGSQSTLFKDSPLRTLK-RKSS--NMKRLSPAPQLGP
SSDAHTSYYSES--LVRESYIGT---AFP------PRSA-LE-E-LHGDADWG-------
---------------------------------------------------EDLRVRRRR
GT--GGSESSRASGLV-GR-KAAEDFLGSSSGYSSEDDYM--------------------
-----GYS-DADQQSSGSR---LWNAVSRAG--SLLW-----------------------
------MVATSPGRLFRLLYWWAGTTWYRLT-TAASLLDVFVLTRR--FS----SLKTF-
LWFLLPLLLLTCLTYGA--WYFYPYGLQTFHPALVSWWAAKD----SRRQDEGWESRDS-
SH---FQAEQRVMSRV--HSLERRLEALAAEFSSNWQKEAMRLER-LELRQGAPGQGG--
------GGGLSHED-----------TLALLEG--L--VSRR------E-AALKEDFRREA
A---------------------A-----RIQEELSA---LRAEHQQDSEDLFKKIVRASQ
ESEARIQQLKSEW----Q--SMTQESFRESSV--KELRRLEDQLAGLQQELAALALKQSL
VADEVGLLPQQIQAVRD-------DVESQFPAWISQFL-AR----G---GGGRVGL-LQR
EEMQA-----QLRELESKIL-THVAEMQG-----KSAREAAASLGMTLQKEGVIGVTEEQ
-----------------------VH----RIVKQALQ-RYSEDRIGLADYALE-------
-----------------SG--GASVIS--TRCSETYETKTALLSLFGIPLWYHSQSPRA-
ILQPDVHPGNCWAFQGPQGFAVVRLSARIRPTAVTLEHVPKA-LSPNSTISSAPKDFAIF
G-----------------F-----DEDLQ-QEGTLLGKFTYDQD-GEPIQ--TFLF--QA
PS--MAT------YQVVELR-------ILTNWGHPEYTCIYRF-R------VHGEPAH--
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------MRRSSRP--------------
------------GSASSSRKH---TPNFFSENSSMSIT--SEDSK--GL-RSAEPGPGEP
EGR--RARGPSCGEPALSAGVPGGTTWAGSSQQKPAPRSHNWQ----TAC-GAA-TVR-G
GASEPTGSPV--VSEE---PLDLLPTLDLRQEMPPP-RVFKSF-----------LSLLF-
----QGLSVLLSLAGDVLVS--MYREVCSIRFLFTAVSLLSLFLSA----------FWLG
LLYLVSPLENPTPR-R---------PPPTSS--------EY----HERVRSQGQQLQQLQ
AELDK-------------LH-KEVSTVRA--------------------------ANSE-
-----------------------------RVAKLVFQ-RLNEDFVRKPDYALS-------
-----------------SV--GASIDL--QKTSHDYADRNTAYFWNRFSFWNYARPPTV-
ILEPHVFPGNCWAFEGDQGQVVIQLPGRVQLSDITLQHPPPS-VEHTGGANSAPRDFAVF
G-----------------L-----QVYD--ETEVSLGKFTF-DVEKSEIQ--TFHL--QN
DP--PAA------FPKVKIQ-------ILSNWGHPRFTCLYRV-RAHGVRTSEGAEGSAQ
G--PH-------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------MKMIQFSARKDLIL-DAVFHSLE--------------------ENGIDGMKREE
-----------------------IL----QLTREAVE-KVMKHYTWLPSWALK-------
-----------------TM--GATIDV--ERTSKSYGGNRWL----SP-FFSSAKPPET-
ILQPDISAGNCWAFQGSRGHVVIRLPEKIWPTAFTLWHISKA-VSPSGEVSTAPREFVVS
G-----------------V-----DED-E-GEA-LLGSFIY-DVDGEIAQ--TFPV--QE
EP--RKA------FRQIKLE-------VRSNWGNAEYTCVYRA-DVHGSPEKN-------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------MRRSPRP--------------
------------GSAATPHKH---NPDFYSDRSNSSVSATSRDSG--SR-SKEGTRIRQG
AGR--DEGSFRDSESIPCAGAAGGHWQAGSCLPIRAPRSRAEP----ASSSKQG-PRRVS
QPPTPHPSPGLAFTP---APQRLLPCLGPSSQMVTPQTMSSPH-----------PAVVL-
----QTLRFFPAVFGEILGAFCRCGEVRSLRFLITASLFFCLFAAA----------IWGA
FLYFTPVWDEETRE------------FLTLS--------EY----HEKVHSQGLQLQQLQ
AELDK-------------LH-TDVSSIRA--------------------------ANSE-
-----------------------------RVAQLVFQ-RLNEDFVQKPDYALS-------
-----------------SV--GASIDL--DKTSHDYEDRDTAYFWNRFSFWNYAKPPTV-
ILEPDVFPGNCWAFKGAKGQVVIRLPGRVQLSDITLQHPPPS-VAHSGGASSAPRDFAVF
G-----------------L-----QGDD--KTEVFLGRFIF-DVEKSEIQ--TFHL--KN
EP--PIA------FPKVKIQ-------ILSNWGHPRFTCLYRV-RAHGLRSHDGHGEDSR
TKGERNGASET-----------------TTPH----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------QLF-
----EVLSVLLSLVGDVLVS--VYREVCTIRFLLTSVSLLSLFLAA----------LWWG
LLYLVPPLENEPKE------------MLTLS--------EY----HESVHSGLQML--LR
AELDK-------------LHXXXXXXXXX--------------------------XXXX-
-----------------------------XXXXXX----XXXXXXXXXXXXXX-------
-----------------XXXXXASIDL--EKTSHDYEDTDTAYFWNRFSFWNYARPPTV-
ILEPDVFPGNCWAFEGDQGQVVIRLPGRVQLSDITLQHPPPS-VAHTGGANSAPRDFAVY
G-----------------L-----QVDD--ETEVFLGKFIF-DVEKSEIQ--TFHL--QN
NP--PAA------FPKVKIK-------ILSNWGHPRFTCLYRV-RAHGVRTSEGAGDSAQ
G--PH-------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MP----------------
--------------R---------------------------SLR----------NPR--
-----D-PCDPPEN-----------A---------RPR--RVAQRGRNTCRMAQDALPNA
--SDAIVLPI---------RINA-PALSLAQCVLAC--ISWITC----------L-ACFL
RTQAHQI----------LFNNCRCRLLFQKLM--EKTGVLVLCAFG-----------FWI
FSMHVPSKMEVWQDDS---------IDSPL----QSLR-MY----QEKVRHHSGEIQDLR
GNMT-------------QLI-AKLQLMEA--------------------------MSDEQ
K-----------------------------MAQKIMK-MIQGDYIEKPDFALK-------
-----------------SI--GASIDF--EQTSATYNYDKARSCWNWIRLWNYAQPPDV-
ILEPNVTPGNCWAFSGDRGQVTIRMAQKVYLSNLTLQHIPKT-ISLSGNLDTAPKDFVIY
-----------------GM---E---G-SPKEEVFLGAFQF-QP-ENIIQ--MFPL--QN
QP--VRA------FGAVKVK-------ISSNWGNPRFTCLYRV-RVHGSVTPPRQL----
------------------------------------------

------------------------------------------------------------
---------------------------------------------------MSRRSQRLT
---RYS-QGDDDGGSSSSGGSSVSGSQSTLFKDSPLRTLK-RKSN--NMKRPSPEPQLGP
SSDPHTSYYSES--LVRESYIGSPRAAFL------ARSA-LE-E-LHSDPDWG-------
---------------------------------------------------DHLRVRKRR
GT--GGSESSRASGLV-VS-KAAEDFLGSSSGYSSEDDYV--------------------
-----GYS-DVDPQSSGSR---LQSVISRVG--SLLW-----------------------
------MVATSPGRLFRLLYWWAGTTWYRLT-TAASLLDVFVLTRR--FS----SLKTF-
LWFLLLLLLLTCLTYGA--WYFYPYGLQTFHPALVSWWTAKD----SRREHEGWESRDSL
PH---FQAEQHVLSRV--HSLERRLEALAAEFSSNWQKEAMRLER-LELRQGTPAQGG--
------SGGLSHED-----------TLALLEG--L--VSRR------E-AALREDFRRET
A---------------------A-----RIQEELAA---LRAEHQQDSEDLFKKIVRASQ
ESEAHIQQLKSEW----Q--SMTQEAFRESSV--KELRRLEDQLAGLQQELAALVQKQSS
VAEEVGLLPQQIQAARD-------DVESKFPAWISEFL-GR----G---GGGGVGL-LQR
EEMQA-----QLRDLESKIL-THITEMQG-----KSAREAAASLGLTLQKEGVIGVTEEQ
-----------------------VH----RIVKQALQ-RYSEDRIGLADYALE-------
-----------------SG--GASVIS--TRCSETYETKTALLSLFGIPLWYHSQSPRV-
ILQPDVYPGNCWAFQGPQGFAVVRLSARIHPTAVTLEHVPKA-LSPNSTISSAPKDFAIF
G-----------------F-----DEDLQ-QEGTLLGKFTYDQD-GEPIQ--TFHF--QA
PM--MAT------YQVVELR-------ILTNWGHPEYTCIYRF-RVHG------EPAH--
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------MLTRSWKII----------LSTVF-
--------------------------------------ISTFLLVG-------LLNHQWL
KETEFPQKPRQLYTVIA-------EYGSRLYNYQARLR-MP----KEQQELLKKESQTLE
NNFREILFLIEQIDVLKALL-KDMKDGVHNH---SLPVHRDAV-----QDQATTDVLDE-
--------------------------EMSNLVHYVLK-KFRGDQIQLADYALK-------
-----------------SA--GASVIE--AGTSESYKNNKAKLYWHGIGFLNYEMPPDM-
ILQPDVHPGKCWAFPGSQGHILIKLARKIIPTAVTMEHISEK-VSPSGNISSAPKEFSVY
-----------------GV-----MKKCE-GEEIFLGQFIY-NKMEATIQ--TFEL--QN
EA--SES------LLCVKLQ-------ILSNWGHPKYTCLYRF-RVHGIPSDYT------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MP----------------
--------------R---------------------------SSR----------NPV--
-----G-PCVLSED-----------MAYNTRP--R-----RLAATLTSPV-------LSA
--DNGILLPA---------HIST-PAVSLTHSMLGY--VSWFNC----------L-ACFL
RTQAQQV----------LFNTCRCKLLCQKLM--EKTGVLLLCALG-----------RFL
L------PSTLFQDDS---------INSPL----QSLR-LY----QEKVRHHSGEIQDLR
GSVN-------------LLI-AKLKEMEA--------------------------MSDEE
K-----------------------------LTQKIMK-MIQGDYIEKPDFALK-------
-----------------SI--GATIDF--EHTSATYNHDKARSYWNWIRLWNYAQPPDV-
ILEPNMTPGNCWAFEGDRGQVTIRLAQKVYLSNITLQHIPKT-ISLSGSLDTAPKDFVVY
-----------------GM---E---S-SPGEEVFLGAFQF-QP-ENIIQ--MFPL--QN
PQ--QRA------FGAVKVK-------ISSNWGNPRFTCLYRV-RVHGSVAPPHRPHASP
QPCPRD------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------M--DGLILFLFCL----------------
---------QVLGPDS------------------TAL-REY----QEMVQLQAREIKDLR
AITD-------------KLL-ATLQEIRA--------------------------MSDEL
TGVCRGMDTINHSFSTAAEAIPLHFSKKKTRVNKILT-MIQGDYIEKPDFALK-------
-----------------SI--GAAIDF--EHTSATYSCSKARSYWNWFRLWDFAHSPEV-
ILEPNVTPGNCWPFLGHHGQVVIRLARKIYLTNVTIQHIPKA-VSLSGNLNAAPKDFAVY
SNGAVARWILPRPRSPRCVLLPSQGVD-DTGEDVFLGAFVF-QA-DSALQ--TFDL--KN
KH--AKP------FGSIKLK-------ITSNWGHPRFTCLYRV-RAHGTMGEPE------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------MRRSSRQ--------------
------------GSASSLSKH---TPNFFSENSSMSVT--SEDSN--RR-RSVGPGPGEL
EGR--RAQGPSCDEPALSAGVPRETTRAESSRQKPAPRSHNRE----TAC-GAA-TVR-G
GASEPTGSTV--VSEE---PLALLPTLDLRQEMPPP-RLSKSF-----------LSLLF-
----QVLRVSLSLVGDALVS--VYREVCTIRFLFTAVSLLSLFLAV----------IWLG
LLYLVSPLENEPK------------EMLTLS--------EY----HERVRSQGQQLQELQ
AELDK-------------LH-KEVSTVRA--------------------------ANSE-
-----------------------------RVAKLVFQ-RLSEDFVRKPDYALS-------
-----------------SV--GASIDL--EKTSHDYADRNTAYFWNRFSFWNYARPPTV-
ILEPDVFPGNCWAFEGDQGHVVIRLPGRVQLSDITLQHPPPS-VAHTGEASSAPRDFAVF
G-----------------L-----QVD---ETEVFLGKFTF-DVEKSEIQ--TFHL--QN
DP--PAA------FPKVKIQ-------ILSNWGHPRFTCLYRV-RAHGMRTSEGAEGSAT
G--GPH------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------MRRSPRP--------------
------------GSAASPHKH---APNFYSDNSNSSMSVTSGDSS--GP-RSARPGPVEP
EGR--RARGSSCGEPALSAGAAGGTSWAGSSRPKPAPRSHNGP----TACGAAT-VRG-G
A-SEPA--PV--LSDE---QLDLLSTLDERQEMPPL-RWSKNF-----------LSVVF-
----QILSVLLYLVGHVLVS--VYREVCSIRFLITVVSLLSFFLTV----------LWWG
FLYLVPPLENEPKE------------MLTLS--------EY----HQRVHSQGEQLQQLQ
AELDK-------------LH-KEVSSVRA--------------------------ANSE-
-----------------------------RVAKLVFQ-RLHEDFVRKPDYALS-------
-----------------SV--GASIDL--EKTSHDYEDTNTAYFWNRFSFWNYARPPTV-
ILEPDVFPGNCWAFEGDQGQVVIRLPGPVQLSDITLQHPPAS-VAHVREANSAPRDFTVY
G-----------------I-----QVDD--ETEVFLGKFTF-DLEKSEIQ--TFPL--QN
DP--PAA------FPKVKIK-------ILSNWGHPRFTCLYRV-RAHGVQMTEGARDSAT
E--GPH------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------MRPPEV-
ILEPDNHPGNCWPFPGSQGHVFIKLPVAVFPTAVTINHGVPAAAYHADSISSAPKDFAVY
IAQQRKFPG------SWGE-----LEEDD-EKGTLLGEFIF-MPGQAPGQ--TFQL--KN
EH--SAF------IKYVRLQ-------VLSNWGHPEYTCVYQF-RLHGDP----------
--APD-----------------GD-ARGKLS---A-------

------------------------------------------------------------
--------------------------------------------------VMSRRSQRLG
AT-RYYQGDDDGSSSG---GSLLLGVQESSFRDSPNRTLR-RKSS--SMKRLSPASHLGP
NPATQTSYYSES--VISESYLGSGRGLAA------GSSAAF-DDPLDSDSYWG-------
---------------------------------------------------GELSTRRRR
GT-G-GTDSSKINGLAES---KTYDTYASSSGYSSEDDYAGRD-----------------
---------CFDTRSMSHE---FRNAVSRAG--SFLW-----------------------
------LVVTSPGRMFGLLYWWIGTAWYRLT-TAASLLDVFVLTRR--YW----ALKKL-
LLCLLLLLLLASIAYGA--WYFYPFGFPMLYPALFS-WGAAKLSPPVAGREEVLGARDSS
AF---FQAEQQMLPRF--QALEKRFQTLEAEAS-----------R-LEKLALQRGAA---
-----AGGGLTHEA-----------TLTLLEG--L--VSRR------E-AALRE----DL
T---------------------L-----HVQSELDT---IQGQLQKDLNRRLEKITQASQ
EVEARMLQLNSEW----Q--SSTQEGLQGSFQ--QEMGRLETQLAGLKKELTLLASDQQA
LVKHIESLPGQIKGVRQ-------DVEAQFPRWISRFL-LQ----PRED-GAGSLV-LPR
EELQD-----KLRELEHRIL-ASVSEGQR-----LSARDAKASIGVALQQEGVTGVTEEQ
-----------------------VH----VIVNRALQ-RYSEDRIGMVDYALE-------
-----------------SGVPGASVIS--TRCSETYETKTALLSLFGIPLWYHSQSPRV-
ILQPDVNPGNCWAFRGSQGFAVIRLSSHIRPTAVTLEHVPKS-LSPVGTIPSAPKDFAVF
G-----------------L-----EEEDQ-QEGILLGQFTYDQD-GDPIQ--TFRL--KG
ED--MGT------FQVVELR-------ILSNWGHPEYTCIYRF-RVHGEQVH--------
------------------------------------------

------------------------------------------------------------
---------------------------------------------------MSRRSQRLT
---RYS-QGDDD-GSSSSGGSSVTGSQSTLFKDSPLRTLK-RKSS--NMKHLSPAPQLDP
SSDSHTSYYSES--VVRESYIGSPRAASL------ARSALLS-DRLQSEPYWS-------
---------------------------------------------------EDLRMRRRR
GT--GGSESSKANGLTTEK-KTSEDFFGSSSGYSSEDDF---------------------
----AGYT-DTNQHSSGSR---LKSAASQAG--SLVW-----------------------
------MLVTFPGRLFSLLYWWVGTTWYRLT-TAASLLDVFVLTRSRRFS----SLKTF-
LWFLLLLLLLTGLTYGA--WYFYPFGLQTFHPAVASWWAAKG-----RRQSEVWESREAS
PH---FQAEQHILSRV--HSLERRLEALAAEFSSNWQKEAIRLER-LELRQGTLGPGGG-
-------GGLSHED-----------TLTLLEG--L--VSRR------E-AALKEDFRRDT
A---------------------A-----RIQEELVT---LRAEHHQDAEDLFKKIVQTSQ
ESEAHVQQLKTEW----Q--RMTQEAFQESSE--KELRRLEAQLAGLRQELAALTLKQNS
VADEIGLLPQKIQAARD-------DVESQFPAWVSQFL-LR----D---GGVRTGL-LQK
EEMRA-----QLQKLESKIL-AHVAEMQG-----KSAKEAAASLGQTLQKEGVVGVTEEQ
-----------------------VH----RIVKQALQ-RYSEDRIGMVDYALE-------
-----------------SG--GASVIS--TRCSETYETKTALLSLFGIPLWYHSQSPRV-
ILQPDVHPGNCWAFQGPQGFAVVRLSARIHPTAVTLEHVPKA-LSPNSTISSAPRDFAIF
G-----------------F-----DEDLQ-QEGTLLGTFTYDQD-GEPIQ--TFYF--QA
LK--MAT------YQVVELR-------ILTNWGHPEYTCIYRF-RVHGEPVH--------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------MLTRSWKII----------LSTIF-
--------------------------------------ASIFFLVG-------LQNYQWF
KETEFRQKPRELYTVIA-------EYGSRLYNYQARLR-MP----KEQLELLKKESQTLE
NNFREILILIEQIDILKALL-RDMKDGVHNH---SWPVHREAV-----QDQVTTAVPDE-
--------------------------EMSNLVHYVLK-KFRGDQIQMADYALK-------
-----------------SA--GASVIE--AGTSESYKNNKAKLYWHGIGFLNYEMPPDM-
ILQPDVHPGKCWAFPGSQGHILIKLARKIIPTAVTMEHISEK-VSPSGNTSSAPKEFSVY
-----------------GI-----KKKCE-GEEMFLGQFIF-NKTETTIQ--TFEL--QN
EA--SES------LLCVKLQ-------IFSNWGHPKYTCLYRF-RVHGIPSDHT------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------MKMIQFSARKDLIL-DAVFHSLE--------------------ENGIDGMKREE
-----------------------IL----QLTREAVE-KVMKHYTWLPSWALK-------
-----------------TM--GATIDV--ERTSKSYGGNRWL----SP-FFSSAKPPET-
ILQPDISAGNCWAFQGSRGHVVIRLPEKIWPTAFTLWHISKA-VSPSGEVSTAPREFVVS
G-----------------V-----DED-E-GEA-LLGSFIY-DVDGEIAQ--TFPV--QE
EP--RKA------FRQIKLE-------VRSNWGNAEYTCVYRA-DVHGSPEKN-------
------------------------------------------

------------------------------------------------------------
---------------------------------------------------MSRRSQRLT
---RYS-QDDNDGGSSSSGASSVAGSQGTVFKDSPLRTLK-RKSS--NMKRLSPAPQLGP
SSDSHTSYYSES--VVRESYIGSPRAVSL------ARSALLD-DHLHSEPYWS-------
---------------------------------------------------GDLRGRRRR
GT--GGSESSKANGLTAES-KASEDFFGSSSGYSSEDDL---------------------
----AGYT-DSDQHSSGSG---LRSAASRAG--SFVW-----------------------
------TLVTFPGRLFGLLYWWIGTTWYRLT-TAASLLDVFVLTRSRHFS---LNLKSF-
LWFLLLLLLLTGLTYGA--WHFYPLGLQTLQPAVVSWWAAKE----SRKQPEVWESRDAS
QH---FQAEQRILSRV--HSLERRLEALAADFSSNWQKEAIRLER-LELRQGAAGHGG--
------GSSLSHED-----------ALSLLEG--L--VSRR------E-ATLKEDLRRDT
V---------------------A-----HIQEELAT---LRAEHHQDSEDLFKKIVQASQ
ESEARVQQLKTEW----Q--SMTQEAFQESSV--KELGRLEAQLASLRQELAALALKQNS
VADEVGLLPQKIQAARA-------DVESQFPDWISQFL-LG----D---RGARSGL-LQR
DELHA-----QLQELENKIL-TKMAEMQG-----KSAREAAASLGQILQKEGIVGVTEEQ
-----------------------VH----RIVKQALQ-RYSEDRIGMVDYALE-------
-----------------SG--GASVIS--TRCSETYETKTALLSLFGIPLWYHSQSPRV-
ILQPDVHPGNCWAFQGPQGFAVVRLSARIRPTAVTLEHVPKA-LSPNSTISSAPKDFAIF
G-----------------F-----DEDLQ-QEGTLLGTFAYDQD-GEPIQ--TFYF--QA
SK--MAT------YQVVELR-------ILTNWGHPEYTCIYRF-RVHGEPAH--------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------MVIGELWRFPGNSSVPYIQVEQPSLLWLALQG-S--------------------
-----------------------------------WE--ATLCPVLFLLTSTLLCLSSQA
-----------------------VQ----KIIHQVLE-KLEESPFQMTNYASK-------
-----------------TS--GAAIVR--SKTSPSWIG-SGRVFWQSLPLVAYMRPPEV-
ILEPDNHPGNCWPFPGSQGHVFIKLPVAVFPTAVTINHGFQQQHTMQTASPVLQRTLLSM
ACRRKMMRK------ERCW-----ES-----SSSCQARLPV-RPSS--------------
------------------------------------------------------------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------MSERPKSRRGAGVYRAHTE----EASGSSS----ITAMLSEP---
------------------------------------------------------------
E---------------------N-----PD---SNWVIWSWKIF----------ISMII-
--------------------------------------VFIFLLVG-------LQNHAWV
KDTDFSQKSRELYAVIA-------EYGSRLSSYQARLC-IP----KEQLELLXXXXXXXX
XXXXXXXXXXXXXXXXXXXX-XXX------X-------------------------XXXX
X-------XXXXXXXXXXXXXXXXXXEMSNLVSYILK-KLREDQVQMADYALK-------
-----------------SA--GASIIE--AGTSESYKNDKAKLFWHGIGFLNYEMPPDV-
ILQPEVHPGKCWAFPGSQGHTLIKLAKKIVPVAVTIEHISEK-ISPSGNILSAPREFSVY
-----------------GI-----SKECK-GEEIFLGQFTY-NKKETTVQ--TFEL--QH
EV--SES------LLCVKLK-------ILSN-EHPTYTCLYRF-RVHGNPGNHTN-----
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MP----------------
--------------R---------------------------PLR----------NPG--
-----DLN---SED-----------VVHGARA--R----RWVTQRGRNTCRT-EDPCPNT
N-D-TLPLPV---------SINA-PALNLIQCMLGC--MSWLTY----------A-ACFL
RTQLQQV----------LSNTCKCKMFCQKLM--EKTGVLVLCAFG-----------FWM
FSIHLPSKMEVWQDDS---------INSPM----QSLR-MY----QEKVRHHAGEIQDLR
GSMN-------------LLI-AKLQEMEA--------------------------MSDEQ
K-----------------------------MAQKIMK-MIQGDYIERPDFALK-------
-----------------SI--GASIDF--EHTSATYNHDKARSYWNWIRLWNYAQPPDV-
ILEPNVTPGNCWAFEGDRGQVTIRLAQKVYLSNLSLQHIPKT-ISLSGSLDTAPKDFVIY
-----------------GM---E---K-SPKEEVFLGAFQF-QP-ENIIQ--TFPL--QN
QP--ARA------FGSVKVK-------VSSNWGNPRFTCLYRV-RVHGSVMPPKEQPN--
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------LTPSWKII----------LCIVI-
--------------------------------------TLAFLLVG-------LQNHQWL
IETEFPQRSRQLYAIIA-------ECGSRLYNYQARLR-MP----KEQLELLKKESQTLE
SNFREILVLIEQIDVLKALL-RDMKDGMHNN---SRPVHRDAT-----QEQHSPDVLDE-
--------------------------EMSNLVHYVLK-KLREDQVQMADYALK-------
-----------------SA--GASIIE--AKTSESYRNNKAKLYWHGIVFLNYEMPPDI-
ILQPDVHPGKCWAFAGAQGHVLIKLARKIQPTAVTMEHISEK-VSPSGNTSSAPKEFSVY
-----------------GV-----LRKCD-GEEVFLGQFTY-NRTETTVQ--TFQL--QH
EV--SES------LLCVKLD-------ILSNWGHPEYTCLYRF-RVHGIPSDHT------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------V--ERTSKSYGGNRWL----SP-FFSSAKPPET-
ILQPDISAGNCWAFQGSRGHVVIRLPEKIWPTAFTIWHISKA-VSPSGEVSTAPREFVVS
G-----------------V-----DED-E-GEA-LLGSFIY-DVDGEIAQ--TFQV--QE
EP--RKA------FRQIKLE-------VRSNWGNKEYTCLYRA-DVHGNPEKA-------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------MRRSPRS--------------
------------GSAASSHNH---TPNFYSENSNSSHSATSGDSN--GR-RSAGPELGEL
EGT--RARGSSCGEPALSPGMPGGDTWAGSSRPTLAPWSHNWQ----TACGAAT-VRG-G
A-SEPSGSS--VVLE----ELNHLPILELREEMPTP-RVSKSF-----------LSLLF-
----QVLSVLLSLAAYGLVC--VCREICSIRFLFTAVSLLSIFLAA----------LWWG
LLYLIPPLENESTE------------MLTVS--------HY----H----SWGQQLQQLQ
AKLNK-------------LH-KEMSSVRV--------------------------AHSE-
-----------------------------RVAKLVFQ-RLNEDFVRKPDYALS-------
-----------------SV--GASIDL--EKTSSDYEDQNTAYFWNRLSFWNYARPPSV-
ILEPYVYPGKCWAFEGDKGQVVIQLPGHVQLSDITLQHPPPT-VAHTRGASSAPRDFAVY
G-----------------L-----QADD--KTEVFLGKFIF-DVQKSEIQ--TFHL--QN
DP--PSA------FPKVKIQ-------ILSNWGHPRFTCLYHV-RAHGVWTSEWADNNAT
G--VTGG-----------------------PH----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------MRRSSRP--------------
------------GSASSSRKH---TPNFFSENSSVSIT--SEDSN--GL-RSAGPGPGDP
EGR--GARGPSCGEPALSAGVPGGTTWAGSSRQKPAPRSHNWQ----TAC-GAA-TVR-G
GASEPTGSPA--VSEE---PLDLLPTLDLRQEMPPS-RVFKSF-----------LSLLF-
----QVLSVLLSLAGDVLVS--MYREVCSIRFLFTAVSLLSLFLAA----------IWLG
LLYLVSPLENPTPR-R---------PPPTSS--------EY----HERVRSQGQQLQQLQ
AELDK-------------LH-KEVSTVRA--------------------------ANSE-
-----------------------------RVAKLVFQ-RLNEDFVRKPDYALS-------
-----------------SV--GASIDL--QKTSHDYADRNTAYFWNRFSFWNYARPPTV-
ILEPHVFPGNCWAFEGDQGQVVIQLPGRVQLSDITLQHPPPS-VEHTGGANSAPRDFAVF
G-----------------L-----QVDD--ETEVFLGKFTF-DVEKSEIQ--TFHL--QN
DP--PAA------FPKVKIQ-------ILSNWGHPRFTCLYRV-RAHGVRTSEGAEGSAT
G--GPH------------------------------------

------------------------------------------------------------
---------------------------------------------------MSRRSQRLT
---RYS-QGDDDGGSSSSGGSSVAGSQSTLFKDSPLRTLK-RKSS--NMKRPSPEPQLGP
SSDPHTSYYSES--LVRESYIGSPRAAFL------ARSA-LE-E-LHSDPDWG-------
---------------------------------------------------DHLRVRKRR
GT--GGSESSRASGLV-GG-KAAEDFLGSSSGYSSEDDYV--------------------
-----GYS-DADPQSSGSR---LQSVVSRVG--SLLW-----------------------
------MVATSPGRLFRLLYWWAGTTWYRLT-TAASLLDVFVLTRR--FS----SLKTF-
FWFLLLLLLLTCLTYGA--WYFYPYGLQTFHPALVSWWAAKD----SRREHEGWESRDSS
PH---FQAEQHVLSRV--HSLERRLEALAAEFSSNWQKEAMRLER-LELRQGTPAQGG--
------SGGLSHED-----------TLALLEG--L--VSRR------E-AALREDFRRET
V---------------------A-----RIQEELAA---LRAEHQQDSEDLFKKIVRASQ
ESEAHIQQLKSEW----Q--SMTQAAFRESSV--KELRRLEDQLAGLQQELAALVQKQSS
VADEVGLLPQQIQAARD-------DVESQFPAWISEFL-AR----G---GGGRMGL-LQR
EEMQA-----QLRDLESKIL-THIAEMQD-----KSAREATASLGLTLQKEGVIGVTEEQ
-----------------------VH----RIVKQALQ-RYSEDRIGLADYALE-------
-----------------SG--GASVIS--TRCSETYETKTALLSLFGIPLWYHSQSPRV-
ILQPDVYPGNCWAFQGPQGFAVVRLSARIRPTAVTLEHVPKA-LSPNSTISSAPKDFAIF
G-----------------F-----DEDLQ-QEGTLLGKFTYDQD-GEPIQ--TFHF--QA
PM--MAT------YQVVELR-------ILTNWGHPEYTCIYRF-RVHG------EPAH--
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MP----------------
--------------R---------------------------SSR----------SPR--
-----D-LCDPPDD-----------VVHVYRN--PRPR--RVIQRGRNICRITEESLSNT
--NDAFLLPI---------RFNT-PVPGLIQCILGC--MSWITC----------L-ACFL
RTQAHQV----------LFNTCRCKLLFQKLM--EKTGVLVLCAFG-----------FWM
FSMHLPSQMQVWQDDS---------INSPL----QSLR-MY----QEKVRHHTGEIQDLR
GNMN-------------QLI-AKLQEMEA--------------------------MSDEQ
K-----------------------------LAQKIMK-MIQGDYIEKPDFALK-------
-----------------SI--GASIDF--EQTSATYNHDKARSYCSWIRLWNYAQPPDV-
ILEPNVTPGNCWAFSGDRGQVTIRLAQKVYLSNLTLQHIPKT-ISLSGSLDTAPKDFVIY
-----------------GM---E---G-SPREEVFLGAFQF-QP-ENIIQ--TFRL--QN
QP--VRN------FGAVKVK-------ISSNWGNPRFTCLYRV-RVHGSVTPPREQPNSP
YLERD-------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------MSGRIKPRRAAQFSQSCSE----EASS-SA---SIHMVLPDQE--
NPDGS-------------------------------------------------------
-----------------------------------GLTQSWKII----------LCTVF-
--------------------------------------TLTFLLIXX-------XXXXXX
XXXXXXXXXXXXXXXX-------XXXXXXXXXXXXXXX-XX----XXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXX--XXXXXX---------------XXXXX
---------------------XXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXX-------
-----------------XX--XASIIE--AGTSESYKNNKAKLYWHGIGFLNYEMPPDI-
ILQPDVHPGKCWAFPGSQGHTLIKLARKIIPTAVTIEHISEK-VSPSGNITSAPKEFSVY
G-----------------I-----TKKCE-GEEIFLGQFIY-NKTGTTVQ--TFGL--Q-
------------------------------------------------------------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------QE
-----------------------IL----QLTQHAME-KIMENGIWRPNWALK-------
-----------------TM--GATVDA--ERTSESYGGKSWKNHCLPP-LLSTAKPPET-
LLQPDISPGNCWAFPRSQGHVVIRLPEEIQLTALTIWHISRA-VSPSGEVSSAPREFAVS
G-----------------V-----DEA-G-GET-LLGLFIY-DVDGEIAQ--TFHL--QE
EP--RKA------FGHVKLE-------VWSNWGNAEHTCVYRV-EIHGNSQKTA------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------MSGKAKARRAAMFFRGCSE----DASGSTS----GSTLLSED---
------------------------------------------------------------
E---------------------N-----PD---TNGVTRSWKII----------LSTMF-
--------------------------------------TLTFLLVG-------LLSHQWL
KETEVPQKSRQLYAIIA-------EYGSRLYKYQARLR-MP----KEQLELLKKESQTLE
NNFHKILLLIEQIDVLKALL-RDMKDGTDNNH--SWNTHGDPV-----EDPDHTEVLDE-
--------------------------EMSNLVNYVLK-KLREDQVQMADYALK-------
-----------------SA--GASIIE--AGTSESYKNNKAKLYWHGISFLNHEMPPDI-
ILQPDVYPGNCWAFPGSQGHTLIKLATKIIPTAVTMEHISEK-VSPSGNISSAPKEFSVY
-----------------GI-----TKKCE-GEEIFLGQFIY-NKTGTTVQ--TFEL--QH
AV--SEY------LLCVKLN-------IFSNWGHPKYTCLYRF-RVHGTPGKHI------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------MEDYS-KYNVYIDFSSCRL----ECNGTIS----AQCNLPLPG--
SSH---------------------------------------------------------
-------------------------------------------------------SPAS-
--------------------------------------ASLLPGIT------GLLSHQWL
KETEDPQKSRRLYAIIA-------EYGSRIYKYQVMFY-IV----RTQMMYFE-------
------------------------------------------------------------
---------------------------LCMLFLY------------FKDY----------
-----------------FIILGASIIE--AGTSESYKNNKAKLYWHGIGFLNHEMPPDT-
ILQPDVYPGKCWAFPGSQGHTLIKLARKIIPTAVTMEHISEK-VSPSGNISSAPKEFSIY
-----------------GI-----TKKCE-GEEIFLGQFIY-NKTGTTIQ--TFEL--QV
MC--ALGNDMSGSITGRDL----------LGLLHAK------------------------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------MSGKAKARRAAMFFRGCSE----DASGSTS----GSTLLSED---
------------------------------------------------------------
E---------------------N-----PD---VNGVTRSWKII----------LSTMF-
--------------------------------------TLTFLLVG-------LLSHQWL
KETEVPQKSRQLYAIIA-------EYGSRLYKYQARLR-MP----KEQLELLKKESQTLE
NNFRKILLLIEQIDVLKALL-RDMKDGTDHNH--SWNTHGDPV-----EDPDHME-----
--------------------------EMSNLVNYVLK-KLREDQVQMADYALK-------
-----------------SA--GASIIE--AGTSESYKNSKAKLYWHGISFLNHEMPPDI-
ILQPDVYPGNCWAFPGSQGHTLIKLATKIIPTAVTMEHISEK-VSPSGNISSAPKEFSVY
-----------------GI-----TKKCE-GEEIFLGQFIY-NKTGTTIQ--TFEL--QH
AV--SEY------LLCVKLN-------IFSNWGHPKYTCLYRF-RVHGTPGKHI------
------------------------------------------

------------------------------------------------------------
---------------------------------------------------MSRRSQRLV
TS-RLYAEDEDG-------SSSLLGGPQLPFKESTARTAARRKSS--GTK------RPSP
GPSTQTSYYSES--LVSESYLGGSRGLAA-----------L-DDALDGGTYWG-------
---------------------------------------------------RELSSRRRR
DT-G-DTESSKVNGLLES---RTYDTYASSSGYSSEDDYAGQL-----------------
---------YSAHSSSGSG---LRTAASRVG--SFLW-----------------------
------QVFTAPARFVGWLLSCIATAWHHVT-GRSPQLQRVPLSRR--YP----RLKKS-
LWWLLLLLLLAAVTYGA--WYLYPYGLSAHSFPVFSWWGVGRLSS-S----DMPGVRDMT
ALDQGLRGEQQLLARF--QALEKRFEALEAAVS-----------R-WELG-----VA---
-----GGEPPPTGD-----------VLGLLDG--L--LGRR------Q-AGMEERLRSDV
T---------------------G-----HLQGELDA---LRTQLQADMDKRLGKMAQASQ
EMEARLQELSREW----Q--RSVQEELQGSWQ--RATGELQQEVSALRRELAGLRSDQEA
MGKHLEAVLEQIKATRA-------DVEAQMPAWISRFL-AQ----PRQDAGTAGLL-LQR
EDLQA-----ELRALELRIL-AQMREERG-----LAARD---SIGVALRQGGAGGVTEEQ
-----------------------VH----LIVDQALK-RYSEDRVGMVDYALE-------
-----------------S--AGASVIN--TRCSETYETKTALLSLFGIPLWYHSQSPRV-
ILQPDVNPGNCWAFRGSQGFAVIRLSSLIRPTAVTLEHVPKA-LSPQGTIPSAPKDFTVY
G-----------------L-----KEERE-EEGLLLGRFTYNQD-GDPIQ--TFYI--KG
DD--VGA------FQLVELR-------VLSNWGHPEYTCIYRF-RVHGEPAL--------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MP----------------
--------------R---------------------------SSR----------SPG--
-----DPGAP-LED-----------VAHNPRP--R----R-IVQRGRNTSRMVEDTSSNM
N-D-NFLLPV---------RINA-QALGLTQCMLGC--VSWFTC----------F-ACSL
RTQAQQV----------LFNTCRCKLLCQKLM--EKTGILLLCAFG-----------FWM
FSIHLPSKMKVWQDDS---------INGPL----QSL-RLY----QEKVRHHSGEIQDLR
GSMN-------------LLI-AKLQEMEA--------------------------MSDEQ
K-----------------------------VAQKIMK-MIHGDYIEKPDFALK-------
-----------------ST--GASIDF--EHTSPTYNHEKAHSYWNWIQLWNYAQPPDV-
ILEPNVTPGNCWAFEGNRGQVTIQLAQKVYLSNLTLQHIPKT-ISPSGSLDTAPKDFVIY
-----------------GM---E---G-SPKEEVFLGAFQF-QP-ESIIQ--MFPL--QN
QP--ARA------FGAVKVK-------ISSNWGNPAFTCLYRV-RVHGSVAPPGEQPHQN
PYPERD------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------MLTRSWKII----------LSTIF-
--------------------------------------ASIFFLVG-------LQNYQWF
KETEFRQKPRELYTVIA-------EYGSRLYNYQARLR-MP----KEQLELLKKESQTLE
NNFREILILIEQIDILKALL-RDMKDGVHNH---SWPVHREAV-----QDQVTTAVPDE-
--------------------------EMSNLVHYVLK-KFRGDQIQMADYALK-------
-----------------SA--GASVIE--AGTSESYKNNKAKLYWHGIGFLNYEMPPDM-
ILQPDVHPGKCWAFPGSQGHILIKLARKIIPTAVTMEHISEK-VSPSGNTSSAPKEFSVY
-----------------GI-----KKKCE-GEEMFLGQFIF-NKTETTIQ--TFEL--QN
EA--SES------LLCVKLQ-------IFSNWGHPKYTCLYRF-RVHGIPSDHT------
------------------------------------------

------------------------------------------------------------
---------------------------------------------------MSRRSQRLT
---RYS-QDDNDGGSSSSGASSVAGSQGTVFKDSPLRTLK-RKSS--NMKHLSPAPQLGP
SSDSHTSYYSES--VVRESYIGSPRAVSL------ARSALLD-DHLHSEPYWS-------
---------------------------------------------------GDLRGRRRR
GT--GGSESSKANGLTAES-KASEDFFGSSSGYSSEDDL---------------------
----AGYT-DSDQHSSGSR---LRSAASRAG--SFVW-----------------------
------TLVTFPGRLFGLLYWWIGTTWYRLT-TAASLLDVFVLTRSRHFS---LNLKSF-
LWFLLLLLLLTGLTYGA--WHFYPLGLQTLQPAVVSWWAAKE----SRKQPEVWESRDAS
QH---FQAEQRVLSRV--HSLERRLEALAADFSSNWQKEAIRLER-LELRQGAAGHGG--
------GSSLSHED-----------ALSLLEG--L--VSRR------E-ATLKEDLRRDT
V---------------------A-----HIQEELAT---LRAEHHQDSEDLFKKIVQASQ
ESEARVQQLKTEW----K--SMTQEAFQESSV--KELGRLEAQLASLRQELAALTLKQNS
VADEVGLLPQKIQAARA-------DVESQFPDWIRQFL-LG----D---RGARSGL-LQR
DEMHA-----QLQELENKIL-TKMAEMQG-----KSAREAAASLGQILQKEGIVGVTEEQ
-----------------------VH----RIVKQALQ-RYSEDRIGMVDYALE-------
-----------------SG--GASVIS--TRCSETYETKTALLSLFGIPLWYHSQSPRV-
ILQPDVHPGNCWAFQGPQGFAVVRLSARIRPTAVTLEHVPKA-LSPNSTISSAPKDFAIF
G-----------------F-----DEDLQ-QEGTLLGTFAYDQD-GEPIQ--TFYF--QA
SK--MAT------YQVVELR-------ILTNWGHPEYTCIYRF-RVHGEPAH--------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------MRRSPRS--------------
------------GSAASPRKH---TPNFYSDNSNSSVSVTSEDSN--GH-RSAGPGPGEP
EGR--RARGSSCGEPALSAGVPGGTTWAGSSRQKPASRSYDGQ----TACGAAT-VRG-G
A-SEPAESPV--VSEE---QLDLLSTLDIRQEMPTP-RVSKSF-----------LSLLL-
----QVLSVLLSLVGDVLVS--VYREVCSIRFLLTAVSLLSLFLAA----------LWLG
LLYLVPPLENEPKE------------MLTLS--------EY----HERVRSQGQQLQQLQ
AELDK-------------LH-KEVSSVRA--------------------------ANSE-
-----------------------------RVAKLVFQ-RLNEDFVRKPDYALS-------
-----------------SV--GASIDL--EKTSHDYEDTSTAYFWNRFSFWNYARPPTV-
ILEPDVFPGNCWAFEGDQGQVVIRLPGRVQLSDITLQHPPPS-VAHTGGANSAPRDFAVF
G-----------------L-----QIDD--ETEVFLGKFTF-DVEKSEIQ--TFHL--QN
DP--PAA------FPKVKIQ-------ILSNWGHPRFTCLYRV-RAHGVRTSEGAGDSAT
G--ATGG-----------------------PH----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------HEH---LPNFYRENSNSSDSVPSGDCS--GH-RSPGPGPGEP
EGR--RARGWSCGEPALRPGLPGGTPWAGSPRQEPAPW----------SHNKGV-WR---
--GEPAASPP--VSEE---QRSLLATLDLRREMPAP-RATKSF-----------LSTLR-
----ASPSSA-----SASLC--SPREVSSVRFLF-AASLLSVFLAA----------SLY-
------------------------------F--------EY----HERVRSHGQQLQQLQ
AELNK-------------LR-KEVARVRA--------------------------AHSE-
-----------------------------RVAKLVFQ-RLNEDFVQKPDYALS-------
-----------------SV--GASIDL--EKTSHDYEDTNMAYFWNRFSFWNYARPPTV-
ILEPDVFPGNCWAFEGDQGQVVIRLAGHVQLSDITLQHPPPS-VAHMGDASSTPRDFAVF
G-----------------L-----WVDN--ETEVFLGKFTF-DVKKSPLQ--TFHL--QN
DP--PSA------FPKVKIQ-------ILSNWGHPRFTCLYRV-RAHGLQISEKGEDS-A
T---VFN-----------------------PH----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MP----------------
--------------R---------------------------PSR----------NPR--
-----D-PCSPSED-----------VAHSSRH--R----R-CNPRGQNTNRAA-------
------------------------------EASSAN--ITWLTC----------L-VCFL
RTQAQEI----------LFNTRRSKLLCQKLM--EKTGVLFLCVFG-----------FWM
LSMHLPSKMEVWQDDS---------INSPL----QSLR-MY----QEMVRHHTGEIQDLR
GSMN-------------QLF-AKLREMEA--------------------------MSDEQ
K-----------------------------MTQKIMK-MIQGDYIEKPDFALK-------
-----------------SL--GASIDF--EHTSATYNHNKARSYWNWIRLWNYAQPPDV-
ILEPNVTPGNCWAFTGDRGQVTIRLAQKVYLSNITLQHIPKT-ISLSGSLDTAPKDFVIY
-----------------GM---E---N-PPREEVFLGAFQF-QP-ENTIQ--MFPL--QN
KP--PRG------FAAVKVK-------ISSNWGNPRFTCLYRV-RVHGSVTLPKESLPE-
SLP---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-LLPDISPGSCWAFQGSQGHVVIRLPEKIQPRAFTIWHISRA-VSPCGEVSSAPEEFAVS
V-----------------S-----LCL-----------LL--LLEGPRAR--GRAL--PE
MS-----------FWW--------------------------------------------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------MSGKAKARRAAMFFRGCSE----DARGSTS----GSTLLSED---
------------------------------------------------------------
E---------------------N-----PD---ANGVTRSWKII----------LSTMF-
--------------------------------------TLTFLLVG------KLLSHQWL
KETEVLRNPEQLYAIIA-------EYGSRLYKYQARLR-MP----KEQLELLKKESQTLE
NNFRKILLLIEQIDVLKALL-RDMKDGTDNNH--SWNTHGDPV-----EDPDHTEVLDE-
--------------------------EMSNLVNYVLK-KLREDQVQMADYALK-------
-----------------SA--GASIIE--AGTSESYKNNKAKLYWHGISFLNHEMPPDI-
ILQPDVYPGNCWAFPGSQGHTLIKLATKIIPTAVTMEHISEK-VSPSGNISSAPKEFSVY
-----------------GI-----TKKCE-GEEIFLGQFIY-NKTGTTVQ--TFEL--QH
AV--SEY------LLCVKLN-------IFSNWGHPKYTCLYRF-RVHGTPGKRI------
------------------------------------------

------------------------------------------------------------
---------------------------------------------------MSRRSQRLV
TT-RYYPGDEDATTS--SSSTSLLGGTQLPFKETTGRTI-RRKSS--STK------RLSP
TPSTQTSYYSES--MMSESYLGGSRGLPA------LGRSLL-DDDLDSSTYWG-------
---------------------------------------------------GELSTRRRR
GT-G-DTESSKINGVLES---KTYDTYTSSSGYSSEDDYAGHY-----------------
---------YSGQSSSGSG---LRTAASRVG--SFLW-----------------------
------QVFTSPVQLLRWLFSGLAGAWRRLT-GTASHLDNVPFSRR--YP----RLKRS-
LLLLLLLLLLAAAAYGA--WYFYPYGLSTLSLPSFPWWGAGKLSSSS----DLPGAGDLT
TLDQG---EHRLLARF--QSLEKRFEALEAELS-----------R-WELRRGAAAVT---
-----AGGEPPPGD-----------ILALLEG--L--VSRR------D-AGLKEHLHTDM
A---------------------N-----HLQGELDV---LRAQVQRDLDGRLGKMAQASQ
EMEARLLELNSEW----Q--SSVQEKLRGTFQ--QEVGKLEQEVAALRRELASLKSDQEV
MGKHVKGILEQLKTVRA-------DVEAQFPAWIGRFL-AQ----SQQD-GAAAFI-LQR
EDLQA-----ELQALERKIL-AKVQEDRR-----LSARDAQAGIGVALRQGGTAGVTEEQ
-----------------------VH----LIVGQALK-RYSEDRVGMVDYALE-------
-----------------S--AGASVIN--TRCSETYETRTALLSLFGIPLWYHSQSPRV-
ILQPDVNPGNCWAFRGSQGFAVIRLSGIIRPTAVTLEHIPKA-LSPQGTIPSAPKDFAVY
G-----------------L-----KEERE-EEGLLLGQFTYNHD-GDPIQ--TFYL--EG
DS--MGT------YQLVELR-------VLSNWGHPEYTCIYRF-RVHGEPAH--------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MP----------------
--------------R---------------------------SSR----------SPG--
-----DPGAL-LED-----------VANNRRP--R----R-IARRGQNTSRMAEDPSPNM
N-D-AFLLPV---------HINA-QAPGLTQCMLGC--VSWVSC----------L-AFFL
RTQAQRV----------LFNTCRCKLLCQKLM--EKTGILLLCAFG-----------FWM
FSIHVPSKMRVGQDDS---------ITTPL----QSLR-LY----QEKVRHHSGEIQDLR
GSIN-------------LLT-AKLQEMEA--------------------------MSNEQ
N-----------------------------MAHKIMK-MIQGDYTEKPDFALK-------
-----------------ST--GASIDF--EHTSATYNHDKAHSYWKWIRLWNYAQPPDV-
ILEPNVTPGNCWAFEGDHGQVTIRLAQKIYLSNLTLQHIPKT-ISLSGNLDTAPKDFVIY
-----------------GM---E---S-SPSEEVFLGAFQF-QP-ENIIQ--MFPL--QN
QP--ARA------FGAVKVK-------ISSNWGNPGFTCLYRV-RVHGSVAPPGAQPHQN
RYPERD------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------MRRSPRP--------------
------------SSAAAPHKH---TPNFYSDNDNNSVSATSGDSS--GH-RSTGPGPGEP
EGR--RARGSSCGEPALSAGVPGGTTWAGSSRQKPAPRSHKGQ----TACGAAT-VPW-A
P-AELAGTSV--VSEE---QLDLLPTLDLRQEMPPP-RVSKSF-----------LNQLF-
----QVLSVLLSLLGDVLVS--ASREVCSIRFLLTAVSLLSLFLAA----------LWWG
LLYLVPPLENEPKE------------MLTMS--------EY----HERVRSQGQQLQQLQ
AELDK-------------LH-KEMSSVRA--------------------------ANSE-
-----------------------------RVAKLVFQ-RLNEDFVRKPDYALS-------
-----------------SV--GASIDL--EKTSRDYEDADTAYFWNRFSFWNYARPPTV-
ILEPDVFPGNCWAFEGDQGQVVIRLPGRVQLSDITLQHPPPS-VAHTRGANSAPRDFAVY
G-----------------L-----QVDD--ETEVFLGKFTF-DVEKSEIQ--TFHL--QN
DP--PAA------FPKVKIQ-------ILSNWGHPRFTCLYRV-RAHGERTSEGAGDSTT
G--VTGG-----------------------LH----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------V--ERTSKSYGGNRWL----SP-FFSSAKPPET-
ILQPDISAGNCWAFQGSRGHVVIRLPEKIWPTAFTIWHISKA-VSPSGEVSTAPREFVVS
G-----------------V-----DED-E-GEA-LLGSFIY-DVDGEIAQ--TFQV--QE
EP--RKA------FRQIKLE-------VRSNWGNKEYTCLYRA-DVHGNPEKA-------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------MRRSPRS--------------
------------GSAASSHNH---TPNFYSENSNSSHSATSGDSN--GR-RSAGPELGEP
EGR--RARGSSCGEPALSPGMPGGDTWAGSSRPKLAPRSHNGQ----TACGAAT-VRG-G
A-SEPSGSS--VVLEE---QLNLLPILDLRQEMPTP-RVSKSF-----------LSLLF-
----QVLSMVLSLAVDGLVC--VCREICSIRFLFTAVSLLSIFLAA----------LWWG
LLYLIPPLENEPTE------------MLTLS--------QY----HHRVHSQGQQLQQLQ
AELNK-------------LH-KEVSSVRA--------------------------AHSE-
-----------------------------RVAKLVFQ-RLNEDFVRKPDYALS-------
-----------------SV--GASIDL--EKTSSDYEDQNTAYFWNRLSFWNYARPPSV-
ILEPDVFPGNCWAFEGDKGQVVIRLPGHVQLSDITLQHPPPT-VAHTGGASSAPRDFAVY
G-----------------L-----QAD-D-ETEVFLGKFIF-DVQKSEIQ--TFHL--QN
DP--PSA------FPKVKIQ-------ILSNWGHPRFTCLYRV-RAHGVRTSEWADDNAT
G--VTGG-----------------------PH----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------MRRSSRP--------------
------------GSASSSRKH---TPNFFSENSSVSIT--SEDSN--GL-RSAGPGPGDP
EGR--GARGPSCGEPALSAGVPGGTTWAGSSRQKPAPRSHNWQ----TAC-GAA-TVR-G
GASEPTGSPL--VSEE---PLDLLPTLDLRPEMPPS-RMFKSF-----------LSLLF-
----QVLSVLLSLAGDVLVS--MYREVCSIRFLFTAVSLLSLFLAA----------IWLG
LLYLVSPLENEPK------------EMLTLS--------EY----HERVRSQGQQLQQLQ
AKLDK-------------LH-KEVSTVRA--------------------------ANSE-
-----------------------------RVAKLVFQ-RLNEDFVRKPDYALS-------
-----------------SV--GASIDL--QKTSHDYADRNTAYFWNRFSFWNYARPPTV-
ILEPHVFPGNCWAFEGDQGQVVIQLPGRVQLSDITLQHPPPS-VEHTGGANSAPRDFAVF
G-----------------L-----QVDD--ETEVFLGKFTF-DVEKSEIQ--TFHL--QN
DP--PAA------FPKVKIQ-------ILSNWGHPRFTCLYRV-RAHGVRTSEGAEGSAT
G--GPH------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MP----------------
--------------R---------------------------SSR----------SPG--
-----DPGVL-PED-----------LAHGARD--A----RP---RS--------------
------------------------YLETITEEPLPN--TTWLTC----------L-ACFL
RTRAQRV----------LFNTCRCKLFFQKLL--EKTGILVLCMFG-----------FWV
CSMHLPSKMEVWQDDN---------PNGPL----QSLR-IY----QEKVRHHTGEIQDLR
GSMN-------------QLI-AKLQEVEA--------------------------MSDEQ
R-----------------------------MAQKIMK-MIQGDYIEKPDFALK-------
-----------------SI--EGGFHFCQSHNNATYNHNKARSYWNWIRLWNYAQPPDV-
ILQPNMTPGNCWAFAGDRGQVTIRLAQKIYLSNLTLQHIPKT-ISLSGSLDTAPKDFVIY
-----------------GM---E---G-TPKEEVFLGAFQF-QP-ENIIQ--MFPL--QN
QP--ARP------FGAVKVK-------ISSNWGNPRFTCLYRV-RIHGSVAPPGD-----
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------MSGKVKSRRRTGLSRSSSE----ETSNSVC----MNVVLP-----
------------------------------------------------------------
-----------------------------------ELTISWKTI----------LSVMF-
--------------------------------------ILIFLLLX-------XXXXXXX
XXXXXXXXXXXXXXXXX-------XXXXXXXXXXVQLR-MP----KEQLELLKKESQILE
NNFHKILVLIEQIDGLKALL-RDMQGRLHNY---SWNTEGDPM-----KVEDHP----E-
--------------------------EMSNLVNYVLK-KLREDQVQMADYALK-------
-----------------SA--GASIIE--AETSETYKNNKAKLYWHGIGFLNYEMPPDI-
ILQPDVHPGKCWAFPGSQGQALIKLARKIIPFAVTMEHISEK-VSPS-NISSAHREFSVY
-----------------GI-----PNQCE-GEDIFLGQFIY-NKTGATVQ--TFEL--QY
EV--SEP------LICVKVK-------ILSNWGHLKYTCLYRF-RVHGTPGNHI------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------MRRSHRP--------------
------------GSAASSHNH---APDFYSENSNSSHSVTSGDSN--GR-RSPGPELEQP
EGR--RARGSSCGEPALSPGVPGGDTRAGS------------------------------
--SRPCGSS--AVLEE---QLNLIPSLDLRQEMPPV-RVSKSF-----------LNLLF-
----QVLSVLLSVAGDALVS--VYREVCSIRFLLTAVTLLSVFLAA----------LWWG
LLYLVPALENEPKE------------MLTLS--------QY----HQRVYSQGQQLQQLQ
TELNK-------------LH-KEVSSVRA--------------------------AHSE-
-----------------------------RVAKLVFQ-RLNEDFVRKPDYALS-------
-----------------SV--GASIDL--EKTSSDYEDTNTVYFWNRLSFWNYARPPSV-
ILEPDVFPGNCWAFEGDQGQVVIRLPGHVQLSDVTLQHPPPT-VAHTGGASSAPRDFAVF
G-----------------L-----QADD--ETEVFLGKFIF-DVQKSEIQ--TFHL--QN
DP--PSA------FPKVKIQ-------ILSNWGHPRFTCLYRV-RAHGVRISEWAEDNAT
G--VAGG-----------------------PH----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------MRRSPRP--------------
------------GSAASPHKR---TPNFYSDNSNSSVSVTSGDSS--GH-RSAGPGPGEP
EGR--RARGSSCGEPVLSAGVPGGTTCAGSPRQKPAPRSHKGP----TACGAAT-VRG-G
A-SEPAGSPV--VSEE---QFDLLPTLDLRQEMPPP-RVSKSF-----------LSLLL-
----RVLSVLLSLVGDVLVI--VYREVCSIRFLLTALSLLSLFLAA----------LWWG
LLYLVPPLENEPKE------------MLTLS--------EY----HERVRSQGQQLQQLQ
AQLDK-------------LH-KEVSSVRA--------------------------ANSE-
-----------------------------RVAKLVFQ-RLNEDFVRKPDYALS-------
-----------------SV--GASIDL--EKTSHDYEDANTAYFWNRFSFWNYARPPTV-
ILEPDVFPGNCWAFEGDQGQVVIRLPGRVQLSDITLQHPPPS-VAHTGGANSAPRDFAVY
G-----------------L-----QVDD--ETEVFLGKFTF-DVEKSEIQ--TFHL--QN
DP--PTA------FPKVKIQ-------ILSNWGHPRFTCLYRV-RAHGMRTSEGAGDSAT
G--EPH------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------V--ERTSKSYGGNRWL----SP-FFSSAKPPET-
ILQPDISAGNCWAFQGSRGHVVIRLPEKIWPTA----------VSPSGEVSTAPREFVVS
G-----------------V-----DED-E-GEA-LLGSFIY-DVDGEIAQ--TFPV--QE
EP--RKA------FRQIKLE-------VRSNWGNKEYTCLYRA-DVHGNPEKA-------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------MP----KEQLELLKKESQNLE
NNFRQILFLIKQIDVLKALL-RDMKDGMDNNH--NWNTHGDPV-----EDLDHTE-----
--------------------------EVSNLVNYVLK-KLREDQVKMADYALK-------
-----------------SA--GASIIE--AGTSESYKNNKAKLYWHGIGFLNHEMPPDI-
ILQPDVYPGKCWAFPGSQGHTLIKLATKIIPTAVTMEHISEK-VSPSGNISSAPKEFSVY
VRSYLNLSF------RLGI-----TKKCE-GEEIFLGQFIY-NKTGTTVQ--TFEL--QH
AV--SEY------LLCVKLN-------IFSNWGHPKYTCLYRF-RVHGTPGKHI------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-LQPSISPGDCWAFRGSQGHVVIRLPVKIWPAAFTIWHISRA-VSPSGEVSSAPKEFAVS
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------ME------R
V---------------------R-----EC---FNQIYWSWKII----------LSMMF-
--------------------------------------LLACLIIG-------FHNSERL
KRTGLSNIPRQLYELST-------DYGSKLYDYQARIR-MP----KVKMELLRVGSHNLE
SNSQEILSLTKQIDILKALL-KDIKNKMDNY---ILNPNTEAF-----GKQDDSDITNE-
--------------------------EMVILVNYVLK-KLREDQVQMADYALK-------
-----------------SA--GASIVE--AGTSESYKNDKAKLYWHGIGFLSYEMPPDV-
ILQPDVHPGKCWAFPGSKGHTIIKLARKITPTAVTMEHISEK-ISPSGNTSSAPKDFSVY
-----------------GL-----KEECK-GEEIFLGQFMY-NKKGTSVQ--TFHL--QN
EV--SEY------LLCVKLK-------ILNNWGHPKYTCLYRF-RVHGKPETDGLGAP--
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------MDASF-
SFQPDISAGNCWAFQGSRGHVVIQLPEKIWPTAFTLWHVSKA-VSPSGEVSTAPREFVVS
G-----------------V-----DED-E-GEA-LLGSFIY-DVDGEIAQ-----T--FP
VQ-----------VWQV----------LAAECQGGRPGCLQVL-GRKGLPDHPGLP---L
LCNAADS-------------CGAD-RRGGRPAFGSTFSSW--

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------MSGKAKARRAAMFFRGCSE----DASGSAS----GSTLLSED---
------------------------------------------------------------
E---------------------N-----PD---ANGVTRSWKII----------LSTMF-
--------------------------------------TLTFLLVG-------LLSHQWL
KETEVPQKSRQLYAIIA-------EYGSRLYKLQARLR-MP----KEQLELLKKESQTLE
NNFRKILLLIEQIDVLKALL-RDTKDGTDNNH--SWNAHGVPV-----EDPDHTE-----
--------------------------EMSNLVNYVLK-KLREDQVQMADYALK-------
-----------------SA--GASIIE--AGTSESYKNNKAKLYWHGIGFLNHEMPPDI-
ILQPDVYPGKCWAFPGSQGHTLIKLATKIIPTAVTMEHISEK-VSPSGNISSAPKEFSVY
-----------------GV-----TKKCE-GEEIFLGQFIY-NKTGTTVQ--TFEL--QH
AV--SEY------LLCVKLN-------IFSNWGHPKYTCLYRF-RVHGTPGKHI------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------MRRSSRP--------------
------------GSASSSRKH---TPNFFSENSSVSIT--SEDSN--GL-RSAGPGPGDP
EGR--GARGPSCGEPALSAGVPGGTTWAGSSRQKPAPRSHNWQ----PAC-GAA-TVR-G
GASGPLPSPP--P---------------------------VPA-----------VGLLF-
----QVLSVLLSLAGDVLVS--MYREVCSIRFLFTAVSLLSLFLAA----------IWLG
LLYLVSPLENEPK------------EMLTLS--------EY----HERVRSQGQQLQQLQ
AELDK-------------LH-KEVSTVRA--------------------------ANSE-
-----------------------------RVAKLVFQ-RLNEDFVRKPDYALS-------
-----------------SV--GASIDL--QKTSHDYADRNTAYFWNRFSFWNYARPPTV-
ILEPHVFPGNCWAFEGDQGQVVIQLPGRVQLSDITLQHPPPS-VEHTGGANSAPRDFAVF
G-----------------L-----QVDD--ETEVFLGKFTF-DVEKSEIQ--TFHL--QN
DP--PAA------FPKVKIQ-------ILSNWGHPRFTCLYRV-RAHGVRTSEGAEGSAT
G--GPH------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------MRRSPRP--------------
------------GSAASQHKH---TPNFYSDNSNSSVSVTSGDSC--GH-RSAGPGPGEP
EGR--RARGSSCGEPALSAGVPGGTTWAGSSRQKPAPRSHNGQ----TACGAAT-VRG-G
A-S---------VSEE---QLDLLPTLDLRQEMPSP-QVSKSF-----------LSLLF-
----QVLSVLLSLVGDVLVS--VYREVCSIRFLLTAVSLLSLFLAA----------LWWG
LLYLAPPLENEPKE------------MLTLS--------EY----HERVRSQGQQLQQLQ
AELVK-------------LH-KEMSSVRA--------------------------ANSE-
-----------------------------RVAQLVFQ-RLSEDFVQKPDYALS-------
-----------------SV--GASIDL--EKTSQDYEDANTAYFWNRFSFWNYARPPTV-
ILEPDVFPGNCWAFEGDQGQVVIRLPGRVQLSDITLQHPPPT-VAHTRGANSAPRDFAVY
G-----------------L-----QVDG--ETEVFLGKFTF-DVEKSEIQ--TFHL--QN
DP--PAA------FPKVKIQ-------ILSNWGHPRFTCLYRV-RAHGIRTSEGAGDSAT
G--GAH------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------MSGKAKARRAAMFFRGCSE----DTSGSTS----GSTLLSED---
------------------------------------------------------------
E---------------------N-----PD---ANGVTRSWKII----------LSTMF-
--------------------------------------TLTFLLVG-------LLSHQWL
KETEVPQKSRQLYAIIA-------EYGSRLYKYQARLR-MP----KEQLELLKKESQTLE
NNFRKILLLIEQIDVLKALL-RDMKDGTDNNH--SWNTHGDPV-----EDPDHTE-----
--------------------------EMSNLVNYVLK-KLREDQVQMADYALK-------
-----------------SA--GASIIE--AGTSESYKNNKAKLYWHGISFLNHEMPPDI-
ILQXXXXXXXXXXXXXXXXXXLIKLATKIIPTAVTMEHISEK-VSPSGNISSAPKEFSVY
-----------------GI-----TKKCE-GEEIFLGQFIY-NKTGTTVQ--TFEL--QH
AV--SEY------LLCVKLN-------IFSNWGHPKYTCLYRF-RVHGTPGKHI------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------MVSLDEELAKVQRQLHVLQWRARDI-T--------------------
------------------------------------E--RALH--EALRRTELPGFTGEA
-----------------------VQ----KIIDQVLE-KLEESPFQMTNYASR-------
-----------------TS--GAAIVR--SKTSPSWIG-SGRVFWQSLPLVAYMRPPEV-
ILEPDNHPGNCWPFPGSQGHVFIKLPVAVFPTAVTINHGVPAAAYHADSISSAPKDFAVY
G-----------------L-----QAEDD-EKGTLLGEFIF-TPGQAPGQ--TFQL--KN
EH--SGF------IKYVRLQ-------VLSNWGHRDYTCVYQF-RLHGDP----------
--AHD-----------------GD-ARGKLS---A-------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------MRRSPRS--------------
------------GSAASSHNH---TPNFYSENSNSSHSATSGDSN--GR-RSAGPELGEP
EGR--RARGSSCGEPALSPGMPGGDTWAGSSRPKLAPRSHNGQ----TACGAAT-VRG-G
A-SEPSGSS--VVLEE---QLNLLPILDLRQEMPTP-RVSKSF-----------LSLLF-
----QVLNMVLSLAVDGLVC--VCREICSIRFLFTAVSLLSIFLAA----------LWWG
LLYLIPPLENEPPE------------MLTLS--------QY----HHRVHSQGQQLQQLQ
AELNK-------------LH-KEVSSVRA--------------------------AHSE-
-----------------------------RVAKLVFQ-RLNEDFVRKPDYALS-------
-----------------SV--GASIDL--EKTSSDYEDQNTAYFWNRLSFWNYARPPSV-
ILEPDVFPGNCWAFEGDKGQVVIRLPGHVQLSDITLQHPPPT-VAHTGGASSAPRDFAVY
G-----------------L-----QAD-D-ETEVFLGKFIF-DVQKSEIQ--TFHL--QN
DP--PSA------FPKVKIQ-------ILSNWGHPRFTCLYRV-RAHGVRTSEWADDNAT
G--VTGG-----------------------PH----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------MSGKTKARRAAMFFRRCSE----DASGSAS----GNALLSED---
------------------------------------------------------------
E---------------------N-----PD---ANGVTRSWKII----------LSTML-
--------------------------------------TLTFLLVG-------LLNHQWL
KETDVPQKSRQLYAIIA-------EYGSRLYKYQARLR-MP----KEQLELLKKESQNLE
NNFRQILFLIEQIDVLKALL-RDMKDGMDNNH--NWNTHGDPV-----EDPDHTE-----
--------------------------EVSNLVNYVLK-KLREDQVEMADYALK-------
-----------------SA--GASIIE--AGTSESYKNNKAKLYWHGIGFLNHEMPPDI-
ILQPDVYPGKCWAFPGSQGHTLIKLATKIIPTAVTMEHISEK-VSPSGNISSAPKEFSVY
-----------------GI-----TKKCE-GEEIFLGQFIY-NKTGTTVQ--TFEL--QH
AV--SEY------LLCVKLN-------IFSNWGHPKYTCLYRF-RVHGTPGKHI------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------VSSV-------PVKETT
VKKSVLCMLLFLIFLSA-LIGAYGGISLARIQWTKDFL-Q-------------------M
LSLQTAP-------RPMNSG-NSLTEETQ---------------GIENQRNGVSYLAEER
---------------------GTVMKVILHFGEEAG--------------MSR-------
-----------------AL--RVSIDL--QRSSRSAWH-----CKV-AWFLCTQNVVET-
FEQLDMSPGYCWPLKASQSQVVFNLPTKVQPTAVTVQHSVETN---LWHVSSAPRDFAVF
G-----------------L-----DEEGE--KEALLGKFTY-DVRKEVTQ--TFQL--QT
ET--PRA------FWHIKLV-------VLNNWGNAGHTCIYRV-QVHGKRAGTNDIGQGH
V-----------------------------------------

------------------------------------------------------------
---------------------------------------------------MSRRSQRLI
---RYSQGDDDGGSSSSSASSSLMIGQHVPFKDSPLRALR-RKSG--SMKRLSPAPHLGS
ASKPHTSYYSES--VVSESYGRGFRAPSV------TKSSILH-EQLDSDSSWS-------
---------------------------------------------------GDLMVGRRR
GI--GGPESSKINMQTED--KISYDTYGSSSGYSSEDDYSETQEG----RPLWGSSFPP-
--CP-TRNLGMDQPSSVSR---LSNAFFQAG--AFLW-----------------------
------MVVTFPGRFFGLFYWWLGTTWYRLT-TAASLLDVFVLTRC--FA----SLKKL-
LLSFLMMMLLASLAFGA--WYFYPYGLKTFHPALFSWWAAKG-----GNKREVWEPVDSN
SY---FKAEQHILSRV--HALERRLETVASEFSALWQKEATRMEH-LELRLQQGAS----
--GNGGVKGLSQED-----------SMIFLEG--L--WSRR------E-AVLKEECRRNA
M---------------------T-----HIQEELTI---LRAEYQQY-LDNQKKIIQAFQ
DLESRFLQLKSDW----QSLSQEEASQRQAA------------VEALQHDVSLCPLVGSG
------ILPRIGHATHA---------PHSKPGNCCRGI-CS----G---IFPSQGQ-EMQ
AMVQA-----QLRDLEHRIL-TQMAEEQG-----KFVRETAARVEQTLDKEGEVGITEEK
-----------------------VH----RIVNQALK-RYSEDRIGLVDYALE-------
-----------------SG--GASVIS--TRCSETYDTKTALLSLFGIPLWYRSQSPRA-
ILQPDVYPGNCWAFQGTQGFAVIRLSALIRPTAVTLEHVPKA-LTPISNIPSAPKDFIIL
G-----------------L-----NEDLQ-QEGAALGYFTYDQN-GEPIQ--TFHL--QS
NN--TAI------YQVVELR-------ILSNWGHPEYTCIYRF-RVHGEPVY--------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------MSPKARS
----GVT-------------------TGSRAGAGPASQLL--------------------
-------------QLLEPA---LSGGVARCHVFQAAWVILMDSPAKNHLGRAPGSTPRSS
PVPGSCCLPSFTV----------CSNTARAGAKNDSPGSPLPLTGRRPQRPGEVRLPPPG
VCPGPGPANPASPPPPPGAWYFYPFGLQSIHPAVVSWWAARD----GRRQQEVWESRDAA
PH---FQAEQRLLSHV--HSLERRLEALAAEFSSTWQKEAVRLER-LELRQGAAGQAG--
-------GGLSQED-----------TLALLDG--L--VSRR------E-AALKEDLRKDA
A---------------------A-----RLQEELAV---LRAEQHRDVEDLFHKIVQAAQ
ESEARVQQLKSEW----QS--SGTRTAQESTL--KELGRLEGQLVSLRHELEALALKQSS
VADEVGLLPQRIQAVRD-------DVESQVPAWITQFL-HR----G---GGARTGL-LQR
EELQA-----QLRELESKIL-AQVAETQG-----TSAREAAAALSLTLQREGVIGVTEEQ
-----------------------VH----RIVKQALQ-RYSEDRIGMVDYALE-------
-----------------SG--EASVIS--TRCSETYETKTALLSLFGIPLWYHSQSPRV-
ILQPDVHPGNCWAFQGPQGFAVVRLSARIRPTAVTLEHVPKA-LSPNSTISSAPRDFAVF
G-----------------F-----DEDLQ-QEGTLLGKFTYDQD-GEPIQ--TFYF--Q-
------------------------------------------------------------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------MRRSSRP--------------
------------GSASSSRKH---TPNFFSENSSVSIT--SEDSN--GL-RSAGPGPGDP
EGR--GARGPSCGEPALSAGVPGGTTWAGSSRQKPAPRSHNWQ----TAR-GAA-TVR-G
GASEPTGSPA--VSEE---PLDLLPTLDLRQEMPPS-RVFKSF-----------LSLLF-
----QVLSVLLSLAGDVLVS--MYREVCSIRFLFTAVSLLSLFLAA----------IWLG
LLYLVSPLENEPK------------EMLTLS--------EY----HERVRSQGQQLQQLQ
AELDK-------------LH-KEVSTVRA--------------------------ANSE-
-----------------------------RVAKLVFQ-RLNEDFVRKPDYALS-------
-----------------SV--GASIDL--QKTSHDYADRNTAYFWNRFSFWNYARPPTV-
ILEPHVFPGNCWAFEGDQGQVVIQLPGRVQLSDITLQHPPPS-VEHTGGANSAPRDFAVF
G-----------------L-----QVDD--ETEVFLGKFTF-DVEKSEIQ--TFHL--QN
DP--PAA------FPKVKIQ-------ILSNWGHPRFTCLYRV-RAHGVRTSEGAEGSAT
G--GPH------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------MVIGELWRFPGNSSVPYIQVEQPSLLWLALQG-S--------------------
-----------------------------------WE--ATLCPVLFLLTSTLLCLSSQA
-----------------------VQ----KIIHQVLE-KLEESPFQMTNYASK-------
-----------------TS--GAAIVR--SKTSPSWIG-SGRVFWQSLPLVAYMRPPEV-
ILEPDNHPGNCWPFPGSQGHVFIKLPVAVFPTAVTINHGVPAAAYHADSISSAPKDFAVY
G-----------------L-----QEEDD-EKGTLLGEFIF-MPGQAPGQ--TFQL--KN
EH--SAF------IKYVRLQ-------VLSNWGHPEYTCVYQF-RLHGDP----------
--APD-----------------GD-ARGKLS---A-------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------MSGRTKTRRAARFFRGCSD----EASSSSS----ANILQSEP---
------------------------------------------------------------
E---------------------N-----PC---TNRLTRPRKII----------LCVIL-
--------------------------------------GLTFLFIG-------LRSLQWL
KEIEFPQKSRQVYSVIG-------EFASRLYNYQARLR-MP----KEQLELLKKESQTLE
NNFREILFLIEQIDVLKALL-RDIKDGVYNQ---SWGAHGDPP-----GSQNTTETLDE-
--------------------------EMSNLVNYVLK-KLREDQVQMADYALK-------
-----------------SA--GASIIE--AGTSESYKNNKAKLYWHGIGFLNYEMPPDI-
ILQPDVYPGKCWAFPGSQGHTLIKLARKIVPTSVTMEHISEK-VSPSGNISSAPKQFSVY
-----------------GI-----LKKCE-GDEIFLGQFIY-NKTGTTVQ--TFKL--QH
AV--SES------VLCVKLK-------ILSNWGHSEYTCLYRF-RVHGTPSVHT------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------MRRSPRP--------------
------------GSAASSHKQ---APDLSSDNSSSSHSVTSGDSN--GP-QS--AELEQP
EGR--RTRGSSCAEPASSPEVSGGAPWAGSSWPKPAPRSHNGQ----TACGSAT-VRG-G
A-SEPAGSPAG--LEE---QLGFLPALDLRQEMPTP-RVSKSF-----------LSFLF-
----QVLSVLLSVTGDVLVS--VYREVCSIRFLFTAASLLSVFLAA----------LWWG
LLYLVPPLENEPKE------------MLTLS--------QY----HQRVHSQGQQLQQLQ
AELNK-------------LH-KEVSSVRA--------------------------AHSE-
-----------------------------RVAKLVFQ-RLNEDFVRKPDYALS-------
-----------------SV--GASIDL--EKTSSDYEDTNTAYFWNRLSFWNYARPPSV-
ILEPDVFPGNCWAFEGDKGQVVIRLPGHVQLSDITLQHPPPT-VAHTGGASSAPRDFAVF
G-----------------L-----QVDD--ETEVLLGKFIF-DVQKSEIQ--TFHL--QN
DP--PSA------FPKVKIQ-------ILSNWGHPRFTCLYRV-RAHGVRISEWAEDNAT
G--VTGG-----------------------PH----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------QARLR-MP----KEQLELLKRESQTLE
NNFREILFLIEQIDVLKALL-REMKDGMYNH---SWNED---P-----VEEQDKGILDE-
--------------------------EMSNLVSYVLK-KLREDQVQMADYALK-------
-----------------SA--GASIIE--AGTSESYKNDKAKLYWHGIGFLNYEMPPDI-
ILQPDVHPGKCWAFAGSQGHTLIKLAKKIVPTAVTMEHISEK-ISPSGNISSAPREFSVY
-----------------GI-----SKECK-GEEIFLGHFMY-NKKETTVQ--TFGL--QH
EV--SEY------LLCVKLK-------ILSNWGHPNYTCLYRF-RVHGNPGNHT------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------MRRSPRT--------------
------------GSAASPRKH---TPNFYSDNSNSSMSVTSEDSN--GH-RSAGPGPGEA
EGR--RARGSSCGEPALSPGVPGGTTWAGSSRQKPAPRSYNGQ----TACGAAT-VRG-G
A-SDPAESPV--VSEE---PLDLLSTLDLRQEMPTP-RVSKSF-----------LSLLF-
----QVLSVLLSLVGDVLVS--VYREVCSIRFLLTAVSLLSLFLAG----------LSSA
PKPCV-----------------------IFP--------EA----HK-IAPRAPSSQGIP
PTVRP-------------VRKSRSSRLRP--------------------------PSFQ-
-----------------------------RVAKLVFQ-RLNEDFVRKPDYALS-------
-----------------SV--GASIDL--EKTSHDYEDTNTAYFWNRFSFWNYARPPTV-
ILEPDVFPGNCWAFEGDQGQVVIRLPGRVQLSDITLQHPPPS-VAHTGGANSAPRDFAVF
G-----------------L-----QVDD--ETEVFLGKFTF-DVEKSEIQ--TFHL--QN
DP--PAA------FPKVKIQ-------ILSNWGHPRFTCLYRV-RAHGVRISEGAGDSAT
G--ATGG-----------------------PH----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MP----------------
------------------------------------------RTR----------NIG--
-----A-LCTLPED-----------TTHSGRP--R----R-GVQRSYISRM-AEPAPAN-
--------------------------------------MTWLTY----------L-ACFL
RTQTQQV----------FLNTCRCKLFCQKVM--EKMGLLVLCVFG-----------FWM
FSMHLPSKVEVWQDDS---------INGPL----QSLR-MY----QEKVRHHTGEIQDLR
GSMN-------------QLI-AKLQKMEA--------------------------ISDEQ
K-----------------------------MAQKIMK-MIQGDYIEKPDFALK-------
-----------------SI--GASIDF--EHTSATYNHDKARSYWNWIRLWNYAQPPDV-
ILEPNVTPGNCWAFASDRGQVTIRLAQKVYLSNITLQHIPKT-ISLSGSLDTAPKDFVIY
-----------------GL---E---S-LPREEVFLGAFQF-QP-ENIIQ--TFQL--QN
LP--PRS------FAAVKVK-------ISSNWGNPRFTCMYRV-RVHGSVTPPKDSHLE-
PLS---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------MRRSPRP--------------
------------GSAASQHKH---TPNFYSDNSNSSVSVTSGDSS--GH-RSARPGPGEP
EGR--RARGSSCGEPALSAGVPGGTTWAGSSRLKPAPRSHNGP----TACGAAT-VRG-G
ASXXXXXXXX--XXXXXX----XXXXXXXXXXXXXX-XXXXXX-----------XXLLF-
----QVLSVLLSLVGDVLVS--VYREVCSIRFLLTAVSLLSLFLAA----------LCWG
LLYLAPPLENEPKE------------MLTLS--------EY----QERVRSQGEQLQQLX
XXXXX-------------XXX---------------------------------------
----------------------------------XXX-XXXXXXXXKPDYALS-------
-----------------SV--GASIDL--EKTSHDYEDANTAYFWNRFSFWNYARPPTV-
ILEPDVFPGNCWAFEGDQGQVVIRLPGRVQLSDITLQHPPPS-VAHTRGANSAPRDFAVY
G-----------------L-----QVDD--ETEVFLGKFTF-DVEKSEIQ--TFHL--QN
EP--PAA------FPKVKIQ-------ILSNWGHPRFTCLYRV-RAHGIRTSERAGDSAT
E--GPH------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MMF-
--------------------------------------TLTFLLVG-------LRNHQWL
KEAEFPQKYRRLHAIVA-------EYGTRVYNYQARLR-MP----REQLELLKRESQALE
NNCREILLLMEQMDMLRALL-RDVKGGTDRDS---GRDPGRVP-----QGQDVTEEPDE-
--------------------------EMFNLVHHILK-KLREDQVQMVDYALK-------
-----------------SA--GASIVE--SETSESYTNNKTKLYWHGIGLLSHEMPPDI-
ILQPDIHPGKCWAFPGSQGHILIRLARKIIPMLVTMEHISEK-VSPSRDTSSAPKEFSVH
-----------------GL-----QKRCG-GEEIFLGQFLY-NNTGSTIQ--TFDL--QH
GI--SES------LLCVRLK-------ILSNWGHPSYTCVYRF-RVHGVPSDLT------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MP----------------
------------------------------------------RTR----------NIG--
-----A-LCTLPED-----------TTHSGRP--R----R-GVQRSYISRT-AEPAPAN-
--------------------------------------MTWLTY----------L-ACFL
RTQTQHV----------FLNTCRCKLFCQKVM--EKMGLLVLCVFG-----------FWV
FSMHLPSKVEVWQDDS---------INGPL----QSLR-MY----QEKVRHHTGEIQDLR
GSMN-------------QLI-AKLQKMEA--------------------------ISDEQ
K-----------------------------MAQKIMK-MIQGDYIEKPDFALK-------
-----------------SI--GASIDF--EHTSATYNHDKARSYWNWIRLWNYAQPPDV-
ILEPNVTPGNCWAFASDRGQVTIRLAQKVYLSNITLQHIPKT-ISLSGSLDTAPKDFVIY
-----------------GL---E---S-LPREEVFLGAFQF-QP-ENIIQ--TFQL--QN
LP--PRS------FAAVKVK-------ISSNWGNPRFTCMYRV-RVHGSVTPPKDSHLE-
PLS---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------NY----QEKVRKHAEEIQALY
SLMK-------------QLS-AKVQEVKV--------------------------MSNEE
L-----------------------------VAQSIMK-KIQGDYIEKPDYALK-------
-----------------ST--GGTIDF--EHTSATYSCDKARSYWSWFRLWNYAHPPDV-
ILEPNMTPGNCWAFSGDRGQVVIRLARKIFLTNITIQHIPKT-ISLSGTVDTAPKDFVVY
-----------------GI---N---D-KSKEEMFLGAFLF-QP-ENFIQ--MFPL--QN
TL--TKP------FNCIKLK-------ILTNWGNPHFTCLYRV-RAHGTVTTVVQPGYLY
SQRN--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MP----------------
--------------R---------------------------SSR----------NPG--
-----D-SCDQPEN-----------VAHVPRE--ARPR--RIIQRGRNICRMTEAPLSNA
--SDAFLLPV---------RINA---PGLTQCMLEC--ISWITC----------L-ACFL
RTRAHQV----------LFNTCRYKLFIHKLI--EKAGVLILCAFG-----------FWM
FSVHLPSKMDIWQEDS---------IDSPL----QSLR-MY----QEKVRHHTGEIQDLR
GHLN-------------QLI-TKLQEMEA--------------------------MSDEQ
K-----------------------------MTQKIIK-MIQGDYIEKPDFALK-------
-----------------SI--GASIDF--EQTSATYNHDKACSYWNWIRLWNYAQPPDV-
ILEPNVTPGNCWAFSGDRGQVTIRLAQKVYLSNLTLQHIPKT-ISLSGSLDTAPKDFVIY
-----------------GM---E---G-SPKEEVFLGAFQF-QP-ENIIQ--TFQL--QN
QP--PRT------FGAVKVK-------ISSNWGDPRFTCLYRV-RVHGSVALPREQPSQS
PHPKRD------------------------------------

------------------------------------------------------------
---------------------------------------------------MSRRSQRLT
---RYSSQGEDDGGSSSSGGSSVMGSQSTLFKDSPLRTLK-KKTN--NSKRLSPAPQLGP
SSDTHT-YYSES--VVRESYIGSPRAASIAA--SLTRHSLLD------DPYWS-------
---------------------------------------------------EDLRVRRRR
GT--GGTDSSKPNGLP-EN-KLSEDFLGSSSGYSSEDDYV--------------------
-----GYS-ETDHQGSGSR---LRNAVSRVG--SLLW-----------------------
------MVVTSPGRLFGLLYWWIGTTWYRLT-TAASLLDVFVLT--RRFS----SLKMF-
LWFLLLLLLLTGLTYGA--WYFYPFGLQTLHPAVVSWWASKG----SIGQREVWESRDSS
PH---FQAEQRILSRV--HSLERRLDALAAEFSSSWQKEAMRLER-LELQQGAGGQG---
----GGGGGLSHED-----------TLALLEG--L--VSRR------E-AALKEDLRRDT
A---------------------A-----RIQEELVT---LRSEHQQDSEDLFKKIVQASQ
ESEARLQQLKSEW----QS-RMTQESFQENAM--KELGRLEGQLAGLRQELAALTLKQSL
VEDQVGLLPQQLQAVRD-------DVESQFPAWVSQFL-LR----G---GGTRTGL-LQQ
EEMEA-----QLRDLESRIL-THVAEMQG-----KSAREAVASLGLTLQREGVIGVTEEQ
-----------------------VH----RIVNQALK-RYSEDRIGMVDYALE-------
-----------------SG--GASVIS--TRCSETYETKTALLSLFGIPLWYHSQSPRV-
ILQPDVHPGNCWAFQGPQGFAVVRLSARIRPTAVTLEHVPKS-LSPNSTISSAPKDFAIF
G-----------------L-----DEDLQ-QEGTPLGQFTYDQD-GEPIQ--TFYF--QD
PK--MAT------YQVVELR-------ILTNWGHPEYTCIYRF-RVHGEPAH--------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------RRRAPAE--------------
------------GSTVPPHKH---TPNFYSDNS--SVSATSADSS--GH-RSAGMGPVEP
EGR--RARGSSCGEPALSAGVSGGTTWAGSSRQKPASRSHKGP----TAGGAAT-VRG-G
A-SEPPGSPV--VSEE---QLDLLSTLDLRQEMPPP-RASKTF-----------LSQLF-
----QVLSVLSSLVGDALVS--AYREVCSIRFLLTAVSLLSLFVAA----------LWWG
LLYLVPPLENEPKE------------MLTLS--------EY----HERVRSQGQQLQQLQ
AELDK-------------LH-KQVASVRA--------------------------TNSE-
-----------------------------RVAKLVFQ-RLNEDFVRKPDYALS-------
-----------------SV--GASIDL--EKTSHDYEDTDTAYFWNRFSFWNYARPPTV-
ILEPDVFPGNCWAFEGDQGQVVIRLPGRVQLSDITLQHPPPS-VAHAGGASSAPRDFAVY
G-----------------L-----QADD--ETEVFLGKFTF-DVEKSEIQ--TFRL--QN
DP--PAA------FPKVKIQ-------ILSNWGHPRFTCLYRI-RAHGVRTSEGAGDSTT
G--ATGG-----------------------PH----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------MSGKIKARMAAIFFRDCSE----EASGSTS----GDALLSEH---
------------------------------------------------------------
E---------------------N-----PD---VNGVTRSRKII----------LSTMF-
--------------------------------------TLTFLLVG-------LLSHQWL
KETEDPQKSRQLYAIIA-------EYGSRLYKYQARLR-MS----KEQLELLKKESQTLE
NNFREILFLIEQIDVLKALL-RGMKDSMDNNH--SWRTHGDPA-----EDPDHTE-----
--------------------------EMSNLVNYVLK-KLREDQVQMADYALK-------
-----------------SA------------DSESYKNDKAKLFWHGNRFPNHEMPPDT-
ILQPDVYPGKCWAFPGSQGHTLIKLARKIIPTAVTMEHISEK-VSPSGNISSAPKEFSVY
-----------------GI-----TKKCD-GEEIFLGQFIY-NNTGTTIQ--TFEL--QH
VA--SEY------LLCVKLN-------IFSNWGHPSYTCLYRF-RVHSTPGTHI------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MP----------------
--------------R---------------------------SSR----------SPG--
-----DPGAL-LED-----------VANNRRP--R----R-IAQRGQNTSRMAEDPSSNM
N-D-AFLLPV---------RINA-QALGLTQCMLGC--MSWVTC----------L-AFFL
RTQAQQV----------LFNTCRCKLLFQKLM--EKTGILLLCAFG-----------FWM
FSVHLPSKMTVWQDDS---------ITSPL----QSLR-LY----QEKVRHHSGEIQDLR
GSMN-------------LLI-AKLQEMEA--------------------------MSDEQ
K-----------------------------MAHKIMK-MIQGDYIEKPDFALK-------
-----------------ST--GASVDF--EHTSATYNHDKAHSYWNWIRLWNYAQPPDV-
ILEPNVTPGNCWAFEGDRGQVTIRLAQKIYLSNLTLQHIPKT-ISLSGSLDTAPKDFVVY
-----------------GM---E---S-SPREEVFLGAFQF-QP-ENIIQ--MFPL--QN
QP--ARA------FGAVKVK-------ISSNWGNPGFTCLYRV-RVHGSVAPPREQPHPN
PYPERD------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MP----------------
------------------------------------------RTR----------NTG--
-----D-LCPISED-----------TTHSGRS--R----R-SAQRSYINRM-AEATPANM
N-D-PLLLPL---------RINP-PGLSLAQFILGY--MSWLTY----------L-ACFL
RTQAQQV----------LLNTCRFKLLFQKLI--EKMGLLVLCVFG-----------FWM
FSMHLPSKMEVWQDDS---------ISGPL----QSLR-MY----QEKVRHHTGEIQDLR
GSMN-------------LLI-AKLQQMEA--------------------------MSDEQ
K-----------------------------MTQKIMK-MIQGDFIEKPDFALK-------
-----------------SI--GASIDF--EHTSPTYNHDKARSYWNWIRLWNYAQPPDV-
ILEPSVTPGNCWAFAGDRGQVTIRLAQKVYLSNVTLQHIPKT-ISLSGCLDTAPKDFVIY
-----------------GM---E---H-PPREEVFLGAFQF-QP-ENIIQ--TFQL--QN
QP--PRG------FAAVKVK-------ISSNWGNPRFTCLYRV-RVHGCATPPKRSYL--
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------WITC----------L-ACFL
RTQIHQA----------LFNNCRLRLFFQKFM--EKTGVLILCVFG-----------FWV
LSMHLPSKLEVWQDDS---------VNSPL----LSLXXXXXXXXXXXXXXXXXXXXXXX
XXXX-------------XXX-XXXXXXXX--------------------------XXXXX
X-----------------------------XXXXXXX-XXXXXXXXXXX-XXX-------
------------------X--XXX-XX-----XXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXPNVTPGNCWAFSGDRGQVTIRLAQKVYLSNLTLQHIPKT-ISLSGSLDTAPKDFVIY
-----------------DM---E---G-PPNEEVFPG-----------------------
------------------------------------------------------------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------MRRSPRP--------------
------------GSAASPHKH---KPNFYSDNSNSSESAISGNSR--GH-RSAGSGPGEL
EGR--RARGSSCGEPALSAGVPGGATWAGSSRPKPAPRSHNGQ----TACGAAT-VRG-G
A-SEPDGAPV--VPEE---QLDL-STLDLRQEMPPR-PVFKSF-----------LSLLF-
----QVLSLLLSLTGDALVS--VYREVCSIRFLLTAVSLLGFFLAV----------LWWG
LLYLVPPLENEPKE------------MLTLS--------EY----HERVRSQGQQLQQLQ
AELDR-------------LH-KEVSSVRS--------------------------ANSE-
-----------------------------RVAKLVFQ-RLNEDFVRKPDYALS-------
-----------------SV--GASIDL--EKTSQDYEDANTAYFWKRFSFWNYARPPTV-
ILEPDVFPGNCWAFEGDQGQVVIRLPGRVQLSDITLQHPPPS-VAHTGGANSAPRDFAVF
G-----------------L-----QVDD--ETEVFLGKFTF-DVKKSEIQ--TFHL--QN
EP--PAA------FPKVKIQ-------ILSNWGHPRFTCLYRV-RAHGVRTSEGAGDSAT
G--VTGG-----------------------PH----------

------------------------------------------------------------
---------------------------PIWA--SG-AFRLSSRGGSPSYVVMSRRSQRLT
---RYS-QGDDDGGSS-SGGSSVMGSQSTLFKDSPLRTLK-RKSS--NMKRLSPAPQLGP
SSDAHTSYYSES--VVRESYFGSPRASSL------ARSSILD-DHLHSDPYWS-------
---------------------------------------------------EDLRGRRRR
GT--GGTESSKLNGLA-EN-KSSEDFLGSSSGYSSEDDFA--------------------
-----GYL-ETDHRSSGSR---LRNAVSWAA--SCFW-----------------------
------TLVTSPGRLFGLLYWWVGTTWYRLT-TAASLLDVFVLT--RRFS----SVKTF-
LWFLLLLLLMTGLTYGA--WYFYPYGLQTLQPAVVSWWAAKS----SSGRQDMWESRDS-
SP---FQAEQHIMSRV--HSLERRLEALAAEFSSNWQKEAVRLER-LELRQGAAGGG---
-----GHVGLSQED-----------TLALLEG--L--VSRR------E-AALKEDFRRDT
A---------------------A-----WIQEELVS---LRAEHQQDSEDLFKKIVQASQ
ESEARIQQLKSEW----Q--RMTQESFRENSM--KELARLEGQLAGLRQELAALSLKQSS
VADQVGLLPQQLQAVRD-------DVESQFPAWVSQFL-LR----G---GGTRTGL-VQR
EELQA-----QLQELESKIL-AHVAEMQG-----RSASEAAASLGLTLQKEGVIGVTEEQ
-----------------------VQ----RIVNQALK-RYSEDRIGMVDYALE-------
-----------------SGVLGASVIS--TRCSETYETKTALLSLFGIPLWYHSQSPRV-
ILQPDVHPGNCWAFQGPQGFAVVRLSARIRPTAVTLEHVPKS-LSPNSTISSAPKDFSIF
G-----------------F-----DEDLQ-QEGTLLGQFTYDQD-GEPIQ--TFYF--QD
TK--MAT------YQVVELR-------ILTNWGHPEYTCIYRF-RVHGEPTH--------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------HEH---LPNFYRENSNSSDSVPSGHCS--GH-RSPGPGPGEP
EGR--RARGSSCGEPALRPGLPGDTPWEPAPRSHNGPT----------VRGAAT-VRG-G
A-SEPAASPP--VSEE---QRSLLATLDLRREMPAP-RATKSF-----------LSTLR-
----ASPSSA-----SASLC--SPREVSSVRFLF-AASLLSVFLAA----------SLY-
------------------------------F--------EY----HERVRSHGQQLQQLQ
AELNK-------------LR-KEVARVRA--------------------------AHSE-
-----------------------------RVAKLVFQ-RLNEDFVQKPDYALS-------
-----------------SV--GASIDL--EKTSHDYEDTNMAYFWNRFSFWNYARPPTV-
ILEPDVFPGNCWAFEGDQGQVVIRLAGHVQLSDITLQHPPPS-VAHMGDASSTPRDFAVF
G-----------------L-----WVDN--ETEVFLGKFTF-DVKKSPLQ--TFHL--QN
DP--PSA------FPKVKIQ-------ILSNWGHPRFTCLYRV-RAHGLQISEKGEDS-A
T---VFN-----------------------PH----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------MVIGELWRFPGNSSVPYVQVEQPSLLWLALQG-S--------------------
-----------------------------------WE--ATLFPVLFLLTSTLLCLSSQA
-----------------------VQ----KIINQVLE-KLEESPFQMTNYASK-------
-----------------TS--GAAIIR--SKTSPSWIG-SGRVFWQSLPLMAYMRPPEV-
ILEPDNHPGNCWPFPGSQGHVFIKLPVAVFPTAVTINHGIPAAAYHADSISSAPKDFAVY
G-----------------L-----QEEDD-EKGTLLGEFIF-TPGQAPGQ--TFQL--KN
EH--SGF------IKYVRLQ-------VLSNWGHPDYTCVYQF-RLHGDP----------
--SHD-----------------GD-ARGKLS---A-------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------MVIGELWRFPGNSSVPYIQVEQPSLLWLALQG-S--------------------
-----------------------------------WE--ATLCPVLFLLTSTLLCLSSQA
-----------------------VQ----KIIHQVLE-KLEESPFQMTNYASK-------
-----------------TS--GAAIVR--SKTSPSWIG-SGRVFWQSLPLVAYMRPPEV-
ILEPDNHPGNCWPFPGSQGHVFIKLPVAVFPTAVTINHGVPAAAYHADSISSAPKDFAVY
G-----------------L-----QEEDD-EKGTLLGEFIF-MPGQAPGQ--TFQL--KN
EH--SAF------IKYVRLQ-------VLSNWGHPEYTCVYQF-RLHGDP----------
--APD-----------------GD-ARGKLS---A-------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MP----------------
--------------R---------------------------SPR----------SPG--
-----DYGA-FTQD-----------QAHGTRD--ARPR--RIAQRNRNTCRLLEEPLPDT
D-PGTFLLPA---------HVIA---PGLTQCMLGF--VXXXXX----------X-XXXX
XXXXXXX----------XXXXXXXXXXXXXXX--XXXXXXXXXXXX-----------XXX
XXXXXXXXXXXXXDPD---------ENNPL----HNLR-FY----QEKVQHHTGEIQDLR
GSMK-------------QLI-ARLQDMEA--------------------------LSDEQ
R-----------------------------KAQKIMK-MIHGDYIEKPDFALK-------
-----------------SI--GATIDF--DHTSATYNHDKARSYWNWIRLWNYAQPPDV-
ILEPNVTPGNCWAFEGDRGQVTIRLPQKIYLSNLTLQHIPKT-ISLSGSLDTAPKDFVVY
-----------------GM---E---G-TPREEVFLGAFQF-QP-ENTIQ--MFSL--QN
QP--ARP------FGAVKVK-------ISSNWGNLRFTCLYRV-RVHGSVAPPGNQPSSP
TRD---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------MDASF-
SFQPDISAGNCWAFQGSRGHVVIRLPEKIWPTAFTIWHISKA-VSPSGEVSTAPREFAVS
G-----------------V-----DED-E-GEA-LLGSFIY-DVDGEIAQ-----T--FP
VQ-----------VWQV----------LAAECQGGRPGCLQVL-GRKGLPDHPGLP---L
LCNAADS-------------CGAD-RRGGRPAFGSTFSSW--

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------MPR---------SRNTGDPGSLCEDPLPW--LTWIAC----------L-AYFL
RTQAQQV----------LFNTCRCRLLFQKLM--EKTGVLVLCVFG-----------FWM
FSMHLPSKMEVWQDDS---------INSPL----QSLR-MY----QEKVRHHTGEIQDLR
GSMN-------------QLI-ARLQEMEA--------------------------MSDEQ
R-----------------------------MTQKIMK-MIQGDYIEKPDFALK-------
-----------------SI--GASIDF--EHTSATYNYEKARSCWNWIRLWNYAQPPDV-
ILEPNMTPGNCWAFSGDRGQVTIRLAQKVYLFNITLQHIPKS-ISLSGSVDTAPKDFVIY
-----------------GM---E---S-SPREEVFLGAFQF-QP-ENTIQ--MFDL--QN
HP--PRA------FGAVKVK-------ISSNWGNPRFTCLYRV-RVHGSVTLPKETPN--
------------------------------------------

------------------------------------------------------------
---------------------------------------------------MSRRSQRLS
---RYS-QGDDDG-SSSSGGSSVTGSQSTLFKDSPLRTLK-RKSS--NMKRPSPAPQLGP
SSDSHTSYYSES--VVRESYIGSPRAASL------ARSALLE-DRLRSEPYWS-------
---------------------------------------------------EDLQVRRRR
GT--GGTESSKTNGLAE----SREDFLGSSSGYSSEDDF---------------------
----AGYP-DVDQPSSGSR---LSSAVSRAG--SFVW-----------------------
------MVLTFPGWLFGLLYWWIGTTWYRLT-TAASLLDVFVLTRSRRFS----SLKPF-
LWFLLLLLLLTGLTYGA--WYVYPHVLQTFHPAVASWWAS-D----SRRHPEAWESRDAS
PP---FQAEQRLLSRV--HALERRLDALAADFSSNWQKEAIRLER-LELRQGSAGHGG--
------GGGLTHED-----------TLALLEG--L--VSRR------E-AALKEDIRKEA
S---------------------A-----RIQEELGT---VRAEHHQDSEDLFKKIVQASQ
ESEARVQQLKSEW----LR--L----TQENSG--KELGRLEAQLANLQQELAALTHKQSS
MAKEVGLLPQKIQAVRD-------DVESQFPTWFGQYL-LR----G---GAAHPSL-LHR
EEVHT-----QLQELERQIL-AHVAEMQG-----KSVSQAAALLGQTLQKEGVVGVTEEQ
-----------------------VH----RIVKQALQ-RYSEDRIGMVDYALE-------
-----------------SG--GASVIS--TRCSETYETKTALLSLFGIPLWYHSQSPRV-
ILQPDVHPGNCWAFQGPQGFAVVRLSARIRPTAVTLEHVPKA-LSPNSTISSAPKDFSIF
G-----------------F-----DEDLQ-QEGTLLGTFTYDQD-GEPIQ--TFYF--QT
PN--MAT------YQVVELR-------ILTNWGHPEYTCIYRF-RVHGEPAH--------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------MSGRPTSRGSTRLFRAPSE----DASSSSS----GSAVLPQQ---
------------------------------------------------------------
E---------------------N-----PD---ASGLTRSWKTV----------MGMVF-
--------------------------------------ILTLLLLG-------FVHHMKR
KEKEFPQKSRQIYALIA-------EYGSRLYNYQARLR-MP----KEQLELLKKESQTLE
NNFREILFLIEQIDVLKALL-RDMRDGLHNY---SWNADIDPT-----EGWNHTEVIDE-
--------------------------EMSTLVNYILK-KLREDQVQMADYALK-------
-----------------SA--GASVVE--AGTSESYKNNKAKLYWHGIGFLNYEMPPDI-
ILQPDVHPGKCWAFPGSQGHALIKLARRIIPTAVTMEHISEK-VSPSGNTSSAPKEFSVY
-----------------GI-----SKQCE-GEEIFLGQFVY-NKTGTTVQ--TFAL--QH
EV--PEF------LLCVKLK-------ILSNWGHPNYTCLYRF-RVHGTPRDDS------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MP----------------
--------------R---------------------------SSR----------SPG--
-----N-SCDPRRN-----------VPKEV-------RSRRVTQRGRNTRRMTEEDLSNT
--SDTFLLPI---------HINA---SGLTQCMLGC--MSWISR------------LCFL
RTQAHQV----------LFNTCRCNLSLCKLM--GKTGVLILCAFG-----------FWM
FSMHLLSKMDVWQDES---------INGPL----QRLR-MY----QEKVQHHAGEIQDLR
GNLN-------------QLI-AKLQKMEA--------------------------MSDEQ
K-----------------------------MAQKIMK-MIQGDYIEKPDFALK-------
-----------------SI--GASIDY--EQTSATYNHDKARSYWNWIRLWNYAQPPDV-
ILEPNMTPGNCWAFSGDRGQVTIQLAQKVYLSNLTLQHIPKT-ISLSGSLDTAPKDFVIY
-----------------GM---E---V-SPKKEVFLGAFQF-QP-ENIIQ--MFQL--QN
HP--PRT------FGAVKMK-------ISSNWGNPRFTCLYRV-RVHGSVTPPREQPNRP
HSERD-------------------------------------

------------------------------------------------------------
---------------------------------------------------MSRRSQRLT
---RYS-QDDND-GSSSSGASSVAGGQSTVFKDSPLRTLK-RKSS--NMKRLSPAPQLPP
PSDSHTSYYSES--VVRESYIGSPRAVSL------ARSALLD-DHLHSEPYWS-------
---------------------------------------------------GDLRGRRRR
GT--GGSESSKANGLTMEN-KASEDFFGSSSGYSSEDDL---------------------
----AGYT-DSDQHSSGSG---LRSAASRAG--SFVW-----------------------
------TLVTLPGRLFGLLYWWVGTTWYRLT-TAASLLDVFVLTRSRHFS---PNLKSF-
LWFLLLLLLLTGLTYGA--WHFYPLGLQTLQPAVASWWAAKE----SRRQPEVWDTRDAS
SH---LQAEQRILSRV--HSLERRLEALAAEFSSNWQKEAIRLER-LELRQGAAGHGG--
------GSSLSHED-----------ALSLLEG--L--VSRR------E-AALKEDLRRDT
V---------------------A-----RIQEELAT---LRAEHHQDSEDLFKKIVQASQ
ESEARVQQLKTEW----R--SMTQEAFQESSV--KELERLEAQLAGLRQELAALTLKQNS
VADEVGLLPQKIQAARA-------DVESQFPDWISQFL-LR----D---RGARSGL-LQR
DEMHA-----QLQELENKIL-ANMAEMQG-----KSAREAAASLGQTLQKEGIVGVTEEQ
-----------------------VH----RIVKQALQ-RYSEDRIGMVDYALE-------
-----------------SG--GASVIS--TRCSETYETKTALLSLFGIPLWYHSQSPRV-
ILQPDVHPGNCWAFQGPQGFAVVRLSARIRPTAVTLEHVPKA-LSPNSTISSAPKDFAIF
G-----------------F-----DEDLQ-QEGTLLGTFAYDQD-GEPIQ--TFYF--QA
SK--MAT------YQVVELR-------ILTNWGHPEYTCIYRF-RVHGEPAH--------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------LS----------------
--------------R---------------------------GSP----------APG--
-----S-P-------------------------------------------------PAP
--GQSVSLRD---------GT--------HGPPVST--AAWFTC----------L-ACFL
RTQAQQV----------LFNTCRFKLLCQKLM--GKAGVLILCAFG-----------FWM
LSMHLPSKMEVWQDGS---------INSPL----KSLR-LY----QEKVRHHTGEIQDLR
GSVN-------------QLI-AKLKEMEA--------------------------MSDEQ
K-----------------------------MVQKIMK-MIQGDYIEKPDFALK-------
-----------------SI--GATIDF--EHTSATYNRDKARSNWNWIRLWNYAQPPDV-
ILEPNMTPGNCWAFEGDHGQVTIRLAQKVYLSNLTVQHIPKT-ISLSGSLDTAPKDFVIY
-----------------GG---PLTWN-SPGEEVFLGAFQF-QP-ENTIQ--MFPL--QN
QQ--LRA------FGAVKVK-------ISSNWGNPHFTCLYRV-RVHGSVALPTQNPAVQ
E-----------------------------------------

------------------------------------------------------------
---------------------------------------------------MSRRSQRLT
---RYS-QGDDDGS-SSSGGSSVAGSQSTLFKDSPLRTLK-RKSS--NMKRLSPAPQLGP
SSDAHTSYYSES--LVRESYIGT---AFP------PRSA-LE-E-LHGDADWG-------
---------------------------------------------------EDLRVRRRR
GT--GGSESSRASGLV-GR-KAAEDFLGSSSGYSSEDDYM--------------------
-----GYS-DADQQSSGSR---LRNAVSRAG--SLLW-----------------------
------MVATSPGRLFRLLYWWAGTTWYRLT-TAASLLDVFVLTRR--FS----SLKTF-
LWFLLPLLLLTCLTYGA--WYFYPYGLQTFHPALVSWWAAKD----SRRQDEGWESRDS-
SH---FQAEQRVMSRV--HSLERRLEALAAEFSSNWQKEAMRLER-LELRQGAPGQGG--
------GGGLSHED-----------TLALLEG--L--VSRR------E-AALKEDFRREA
A---------------------A-----RIQEELSA---LRAEHQQDSEDLFKKIVRASQ
ESEARIQQLKSEW----Q--SMTQESFRESSV--KELRRLEDQLAGLQQELAALALKQSL
VADEVGLLPQQIQAVRD-------DVESQFPAWISQFL-AR----G---GGGRVGL-LQR
EEMQA-----QLRELESKIL-THVAEMQG-----KSAREAAASLGVTLQKEGVIGVTEEQ
-----------------------VH----RIVKQALQ-RYSEDRIGLADYALE-------
-----------------SG--GASVIS--TRCSETYETKTALLSLFGIPLWYHSQSPRV-
ILQPDVHPGNCWAFQGPQGFAVVRLSARIRPTAVTLEHVPKA-LSPNSTISSAPKDFAIF
G-----------------F-----DEDLQ-QEGTLLGKFTYDQD-GEPIQ--TFHF--QA
PS--MAT------YQVVELR-------ILTNWGHPEYTCIYRF-R------VHGEPAH--
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------MRRSTRP--------------
------------GSVTSPDEH---APNFYSENSNSSESIPSGNCS--GR-RSPGPGPGEP
EGR--RARGASCGEPALRSGLPGGTPWAGSSRQESAPRNHNAE----TACGAAT-VRG-G
A-SELAASPA--VSEE---QRSLLATLDPRREMPAL-RVTKSF-----------LSLLF-
----QVLRVLLSQVRDALLG--VCREVCSARFLF-ATSLLSIFLAA----------LSWG
LLHLFPPLENEPKA------------MLTPS--------EY----HDRVRSHGQQLQQLQ
AELNK-------------LR-KEVIRVRE--------------------------AHSE-
-----------------------------RVAKLVFQ-RLNEDFVQKPDYALS-------
-----------------SV--GATIDL--EKTSQDYEDTNTAYFWNRFSFWNYARPPTV-
ILEPDVFPGNCWAFQGDQGQVAIRLAGRVQLSHITLQHPPPS-VAHTGDASSAPRDFAVF
G-----------------L-----QVDD--DTEVFLGRFTF-DVKKSAIQ--TFHL--QN
DP--PSA------FPKVKIQ-------ILSNWGHPRFTCLYRV-RVHGLRISEGEDSA-T
G--ATGG-----------------------PH----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------MRRSPRP--------------
------------GSAKSPHKH---TSNFYSDNSNSSVSVTSRDSS--GQ-RSAGPGPGEP
EGR--RARGSSCGEPALSAGVPGGTTWAGSSRQKPAPRSHNGQ----TACGAAT-VRG-G
A-SEPAGSPV--ASEE---QLDLLSTLDLRQEMPPP-RVSKNF-----------LSLLL-
----QVLSVLLSLVGDALVI--VYREVCSIRFLLTAVSLLSLFLAA----------LWWG
LLYLVPPLENEPKE------------MLTLS--------EY----HERVRSQGQQLQQLQ
AELDK-------------LH-KEVSSVRA--------------------------ANSE-
-----------------------------RVAKIVFQ-RLNEDFVRKPDYALS-------
-----------------SVAPGASIDL--EKTSHDYEDANTAYFWNRFSFWNYARPPTV-
ILEPDVFPGNCWAFEGDQGQVVIRLPGRVQLSDVTLQHPPPS-VAHTGGANSAPRDFAVY
G-----------------L-----QVDD--ETEVFLGKFTF-DVEKSEIQ--TFHL--QN
DP--PAA------FPKVKIQ-------ILSNWGHPRFTCLYRV-RAHGMRTSEGAGDSAT
G--EPH------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MP----------------
--------------R---------------------------PAR----------SPG--
-----DSGAL-PED-----------LVHGARD--TRA--RRITQRSRNPCRVASESSPNM
N-PDTFLFPI--------------NAPGLIHCMLGW--TSWVTN----------M-ACTL
RTWTQHT----------LFNTCRFKLFFQMIM--EKTGILILCGFG-----------FWV
LSIHVPSKVEVWQDDS---------IKNPL----QSLR-MY----QEKVRHHAGEIQDLR
GNMN-------------QLI-AKLQEMEA--------------------------MSDEQ
K-----------------------------MAQKIMK-MIHGDYIEKPDFALK-------
-----------------SI--GATIDF--EHTSPTYNHDKARSYWNWIRLWNYAQPPDV-
ILEPNVTPGNCWAFAGDRGQVTIRLAQKVYLSNLTLQHIPKT-ISLSGSLDTAPKDFVIY
-----------------GM---E---G-YPKEEVFLGAFQF-QP-ENTIQ--MFPL--QN
QP--ARP------FGAVKVK-------ISSNWGHPRFTCLYRV-RIHGSVAPPRGAGSPA
PSGPPRP-----------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------MSGRPTSRGG-SLFRAPSE----DASSSSS----GSAVLPQQ---
------------------------------------------------------------
E---------------------N-----PD---ASGLTRSWKTV----------MGMVF-
--------------------------------------ILTLLLLG-------FVHHMKH
KEKEFPQKSRQIYALIA-------EYGSRLYNYQARLR-MP----KEQLELLKQESQTLE
NNFREILFLIEQIDVLKALL-RDMRDGLHNY---SWNADIDPT-----EGWNHTEVIDE-
--------------------------EMSTLVNYILK-KLREDQVQMADYALK-------
-----------------SA--GASVVE--AGTSESYKNNKAKLYWHGIGFLNYEMPPDI-
ILQPDVHPGKCWAFPGSQGHALIKLARRIIPTAVTMEHISEK-VSPSGNTSSAPKEFSVY
-----------------GI-----SKQCE-GEEVFLGQFVY-NKTGTTVQ--TFAL--QR
EV--PEF------LLCVKLK-------ILSNWGHPNYTCLYRF-RVHGTPRDDS------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------MRRSSRP--------------
------------GSASSPRKH---TPNFFSENSSMSVT--SEDSN--GR-RSAGPEPGEP
EGR--IAQGRSCGEPALSAGVPGGTTWAGSSQQKPAPRSHNAE----TAC-GAA-TVR-G
GASEPTGSPV--VSEE---PLALLPTLDLRQEMPPP-RLSKSF-----------LSLLF-
----QVLRVSLSLAGNALVS--VYREVCSIRFLFTAVSLLSLFLAV----------IWLG
LLYLVSPSENPTPR-R---------PPPTSS--------EY----HERVRSQGQQLQQLQ
AELDK-------------LH-KEVSTVRA--------------------------ANSE-
-----------------------------RVAKLVFQ-RLSEDFVRKPDYALS-------
-----------------SV--GASIDL--EKTSHDYADRNTAYFWNRFSFWNYARPPTV-
ILEPDVSPGNCWAFEGDQGHVVIRLPSRVQLSDITLQHPPPS-VAHTGGADSAPRDFAVF
G-----------------L-----QVDD--ETEVFLGKFTF-NVEKSEIQ--TFHL--QN
DP--PAA------FPKVKIQ-------ILSNWGHPRFTCLYRV-RAHGVRTSEGAEGSAT
G--GPH------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------MDASF-
SFQPDISAGNCWAFQGSRGHVVIRLPEKIWPTAFTIWHISKA-VSPSGEVSTAPREFVVS
G-----------------V-----DED-E-GEA-LLGSFIY-DVDGEIAQ-----T--FQ
VQ-----------VWQV----------LAAECQGGRPGCLQVL-GRKGLPDHPGLP---L
LCNAADS-------------CGAD-RRGGRPTFGSTFSSW--

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------MSGRPKPRRGARTLTGHSE----EAGGSAS----LHIPLAEDG--
SREASRYAAPGRD-------------------------------------GRA------P
R---------------------S-----AA---SQRLTQSWKIV----------ISAVS-
--------------------------------------ILTLLLIG-------LGNHMWL
QETEFPHKSRQFYALIA-------EYGSRLYNYQARLR-MP----KEQLELLKKESQTLE
NNFREILFLIEQIDVLKALL-RDTQDGLHSH---SWNVDGDWD-------QEPPEATDE-
--------------------------EMSNLVNYVLK-KLREDQVQMADYALK-------
-----------------SA--GASVIE--AGTSESYKNNKAKLYWHRIGFLTYEMPPDI-
ILQPDVHPGKCWAFPGSQGHVLIKLAGRIMPTAITMEHISEK-VSPSGNISSAPKEFSVH
-----------------GI-----SKQCD-GEEIFLGQFIY-DKTGSTVQ--TFEL--QR
NV--SES------LLCVKLK-------ILSNWGHPKYTCLYRF-RVHGTPGE--------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------MRRSPRS--------------
------------GSAASSHNP---APDFFSENSNSSHSVTSGDSN--GR-RSAGPELEQP
EGR--RARGSSCGEPAISPGVPGGDTWAGSSLPKPAPRSHNGQ----TACGAAT-VRG-G
A-SGPGGERAGRPLGE---QLNLLPALDLRQEMPPT-RMSKSF-----------LSLLF-
----QVLSVLLSVAGDALVS--VYREVCSIRFLFSSLSLLSIFLAV----------FWWG
LLYLVPTLENEPQE------------MLTLS--------QY----HQRVHSQSQQLQQLQ
KELNN-------------LH-KEVSSVRA--------------------------AHSE-
-----------------------------RVAKLVFQ-RLNEDFVRKPDYALS-------
-----------------SV--GASIDL--EKTSSDYKDTNTAYFWNRLSFWSYARPPSV-
ILEPDVFPGNCWAFEGDQGQVVIRLPGHVQLSDITLQHPPPT-VAHTGGASSAPRDFAVF
G-----------------L-----QADD--ETEVFLGKFTF-DVQKSEIQ--TFHL--QN
DP--PSA------FPKVKIQ-------IRSNWGHPRFTCLYRV-RAHGVRISEWAD-NAT
G--VTGG-----------------------PN----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------MKMIQFSARKDLIL-DAVFHSLE--------------------ENGIDGMKREE
-----------------------IL----QLTREAVE-KVMKHDTWLPSWALK-------
-----------------TM--GATIDV--ERTSKSYGGNRWL----SP-FFSSAKPPET-
ILQPDISAGNCWAFQGSRGHVVIRLPEKIWPTAFTIWHISKA-VSPSGEVSTAPESLLSQ
G-----------------V-----DED-E-GEA-LLGSFIY-DVDGEIAQ--TFPV--QE
EP--RKA------FRQIKLE-------VRSNWGNAEYTCVYRA-DVHGSPEKN-------
------------------------------------------

------------------------------------------------------------
---------------------------------------------------MSRRSQRLT
---RYS-QGDEDGS-SSSGGSSVAGSQSTLFKDSPLRTLK-RKSS--NMKRLSPAPQLGP
SSDAHTSYYSES--LVRESYIGT---AFP------PRSA-LE-E-LHGDADWG-------
---------------------------------------------------EDLRVRRRR
GT--GGSESSRASGLV-GR-KAAEDFLGSSSGYSSEDDYV--------------------
-----GYS-DADQQSSGSR---LRNAVSRAG--SLLW-----------------------
------MVATSPGRLFRLLYWWAGTTWYRLT-TAASLLDVFVLTRR--FS----SLKTF-
LWFLLPLLLLTCLTYGA--WYFYPYGLQTFHPALVSWWAGKD----SRRQDEGWESRDS-
SH---FQAEQRVMSRV--HSLERRLEALAAEFSSNWQKEAMRLER-LELRQGAPGQGG--
------GGGLSHED-----------TLALLEG--L--VSRR------E-AALKEDFRREA
A---------------------A-----RIQEELSA---LRAEHQQDSEDLFKKIVRASQ
ESEARIQQLKSEW----Q--SMTQESFRESSV--KELRRLEDQLAGLQQELAALALKQGL
VADEVGLLPQQIQAVRD-------DVESQFPAWISQFL-AR----G---GGGRVGL-LQR
EEMQA-----QLRELESKIL-THVAEMQG-----KSAREAAASLGVTLQKEGVIGVTEEQ
-----------------------VH----RIVKQALQ-RYSEDRIGLADYALE-------
-----------------SG--GASVIS--TRCSETYETKTALLSLFGIPLWYHSQSPRV-
ILQPDVHPGNCWAFQGPQGFAVVRLSARIRPTAVTLEHVPKA-LSPNSTISSAPKDFAIF
G-----------------F-----DEDLQ-QEGTLLGKFTYDQD-GEPIQ--TFHF--QA
PS--MAT------YQVVELR-------ILTNWGHPEYTCIYRF-R------VHGEPAH--
------------------------------------------

------------------------------------------------------------
---------------------------------------------------MSRRSQRLT
---RYS-QGDDDGS-SSSGGSSVAGSQSTLFKDSPLRTLK-RKSS--NMKRLSPAPQLGP
SSDAHTSYYSES--LVRESYIGT---AFP------PRSA-LE-E-LHGDADWG-------
---------------------------------------------------EDLRVRRRR
GT--GGSESSRASGLV-GR-KAAEDFLGSSSGYSSEDDYM--------------------
-----GYS-DADQQSSGSR---LRNAVSRAG--SLLW-----------------------
------MVATSPGRLFRLLYWWAGTTWYRLT-TAASLLDVFVLTRR--FS----SLKTF-
LWFLLPLLLLTCLTYGA--WYFYPYGLQTFHPALVSWWAAKD----SRRQDEGWESRDS-
SH---FQAEQRVMSRV--HSLERRLEALAAEFSSNWQKEAMRLER-LELRQGAPGQGG--
------GGGLSHED-----------TLALLEG--L--VSRR------E-AALKEDFRREA
A---------------------A-----RIQEELSA---LRAEHQQDSEDLFKKIVQASQ
ESEARIQQLKSEW----Q--SMTQESFQESSV--KELRRLEDQLAGLQQELAALALKQSL
VADEVGLLPQQIQAVRD-------DVESQFPAWISQFL-AR----G---GGGRVGL-LQR
EEMQA-----QLRELESKIL-THVAEMQG-----KSAREAAASLGVTLQKEGVIGVTEEQ
-----------------------VN----RIVKQALQ-RYSEDRIGLADYALE-------
-----------------SG--GASVIS--TRCSETYETKTALLSLFGIPLWYHSQSPRV-
ILQPDVHPGNCWAFQGPQGFAVVRLSARIRPTAVTLEHVPKA-LSPNSTISSAPKDFAIF
G-----------------F-----DEDLQ-QEGTLLGKFTYDQD-GEPIQ--TFHF--QV
RD--SAV------LAKAAQ------------TAHPGSRRSLDT-YPAGHGVQRGKPCPPF
PQLKM-------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MP----------------
------------------------------------------RTR----------NVG--
-----A-LYTLPQD-----------TTHSGRP--R----R-GVQRSCMSRM-AEPAPAN-
--------------------------------------MTWLTY----------L-ACFL
RTQAQQV----------FLNTCRCKFFCQKVM--EKMGLLVLCVFG-----------FWM
FSMHLPSKVEVWQDDS---------ISGPL----QSLR-MY----QEKVRHHTGEIQDLR
GSMN-------------QLI-AKLQEMEA--------------------------ISDEQ
K-----------------------------MAQKIMK-MIQGDYIEKPDFALK-------
-----------------SI--GASIDF--EHTSATYNHDKARSYWNWIRLWNYAQPPDV-
ILEPNVTPGNCWAFAGDRGQVTIRLAQKVYLSNITLQHIPKT-ISLSGSLDTAPKDFVIY
-----------------GL---E---S-LPKEEVFLGAFQF-QP-ENIIQ--MFQL--QN
LP--PRS------FAAVKVK-------ISSNWGNPRFTCMYRV-RVHGSVTPPKDSHIK-
PLS---------------------------------------

------------------------------------------------------------
---------------------------------------------------MSRRSQRLS
---RYS-QGDDDGGSS-SGGSSVMGSQSTLFKDSPLRTLK-RKSS--NMKRLSPAPQLGP
SSDDHTSYYSES--VVRESYFGSPRAASL------ARSSILD-DHLHSEPYWG-------
---------------------------------------------------EDLRVRRRR
G-----TESSKLNGLA-EN-RSSEDFLGSSSGYSSEDDFA--------------------
-----GYS-ETDHHSSGSR---LRNAVSWAA--SCLW-----------------------
------TLVTSPGRLFGLLYWWVGTTWYRLT-TAASLLDVFVLT--RRFS----SVKTF-
LWFLLLLLLTTGLTYGA--WYFYPYGLQTFHPALVSWWASKS----SGRQQDVWEPRDS-
SH---FQAEQRILSRV--HSLERRLEALAAEFSSNWQKEAMRLER-LELRQGAAGGG---
-----GHVGLSQED-----------TLELLEG--L--VSRR------E-AALKEDFRRDT
A---------------------A-----QIQEELVT---LRAEHHRDSEDLLKKIVQASQ
ESEARLQQLKSEW----Q--RMTQEAFRENSA--KELGRLEGQLAALRQELAALSLKQSS
VADQVGLLPQQLQAVRD-------DVESQFPAWVSQYL-LR----G---GGTRAGL-LQR
EEMQA-----QLQELERKIL-AHVAEMQG-----KSAREAAASLGLTLQKEGVIGVTEEQ
-----------------------VQ----RIVNQALK-RYSEDRIGMVDYALE-------
-----------------SG--GASVIS--TRCSETYETKTALLSLFGIPLWYHSQSPRV-
ILQPDVHPGNCWAFQGPQGFAVVRLSARIRPTAVTLEHVPKS-LSPNSTISSAPKDFSIF
G-----------------F-----DEDLQ-HEGTLLGQFTYDQD-GEPIQ--TFYF--QD
PK--MAT------YQVVELR-------ISTNWGHPEYTCIYRF-RVHGEPAH--------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MP----------------
--------------R---------------------------SSR----------SPV--
-----D-LCDLPED-----------VV--------RPR--RVAPRGRNTCRVTEDNLSNL
NQSDAFVLPI---------RLSA-PAPGLTQCLLAC--VSWITC----------L-ACFL
RTQAHQI----------LFNTCRWARAGEKLM--EKTGVLVLCAFG-----------FWM
FSMHLPSKMEVWQDDS---------INSPL----QSLR-MY----QEKVRHHTGEIQDLR
GNMT-------------QLI-AKLQLMEA--------------------------MSDEQ
K-----------------------------IAQKIMK-MIQGDFIEKPDFALK-------
-----------------SI--GASIDF--EQTSTTYNHNKARSYWNWIRLWNYAQPPDV-
ILEPNMTPGNCWAFSGDRGQVTIRLAQKVYLSNLTLQHIPKT-ISLSGSLDTAPKDFVIY
-----------------GM---E---G-SPKEEVFLGAFQF-QP-ENIIQ--MFQL--QN
QP--ARA------FGAVKVK-------ISSNWGNPRFTCLYRV-RVHGSVTPPR------
------------------------------------------

MSSSL------------------------VECTGVCVLLEAVSCLSFPPLPPRPQG----
--------------------EAESSPEPHLA--AFLSPDSLQGKGPPAHLIMSRRSQRLT
---RYSSQGDDDGGSSSSGGSSVMGSQSTLFKDSPLRTLK-KKSN--NSKRLSPAPQLGP
SSDTHTSYYSES--VVRESYIGSPRAASIAA--SLTRNSLLD------DPYWS-------
---------------------------------------------------EDLRVRRRR
GT--GGTDSSKVNGLP-EN-KLSEDFLGSSSGYSSEDDYV--------------------
-----GYS-ETDHQGSGSR---LRNAVSRAG--CLLW-----------------------
------MVVTSPGRLFGLLYWWIGTTWYRLT-TAASLLDVFVLT--RRFS----SLKTF-
LWFLLLLLLLTGLTYGA--WYFYPFGLQTLHPAVVSWWASKG----SIGQREVWESRDSS
PH---FQAEQRILSRV--HSLERRLDALAAEFSSSWQKEAMRLER-LELQQGAGRQG---
----GGGGGLSHED-----------TLALLEG--L--VSRH------E-AALKEDLRRDT
A---------------------A-----RIQEELVT---LRSEHQQDSEDLFKKIVQASQ
ESEARLQQLKSEW----Q--RMTQESFQENAM--KELGRLEGQLAGLRQELAALTLKQSS
VEDQVGLLPQQLQAVRD-------DVESQFPAWVSQFL-LR----G---GGTRTGL-LQR
EEMEA-----QLRDLESKIL-THVAEMQS-----KSAREAVASLGLTLQREGVIGVTEEQ
-----------------------VH----RIVSQALK-RYSEDRIGMVDYALE-------
-----------------SG--GASVIS--TRCSETYETKTALLSLFGIPLWYHSQSPRV-
ILQPDVHPGNCWAFQGPQGFAVVRLSARIRPTAVTLEHVPKS-LSPNSTISSAPKDFAIF
G-----------------F-----DEDLQ-QEGTLLGQFTYDQD-GEPIQ--TFYF--QD
PK--MAT------YQVVELR-------ILTNWGHPEYTCIYRF-RVHGEPAH--------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------MEDYS-KYNVYIDFSSCRL----ECSGMIS----AHCNLH-----
------------------------------------------------------------
---------------------------------LPGSSN----------------SPVS-
--------------------------------------VSRVPGAT------GLLSHQWL
KETEVPQKSRQLYAIIA-------EYGSRLYKYQARLR-MP----KEQLELLKKESQTLE
NNFHKILLLIEQIDVLKALL-RDMKDGTDNNH--SWNTHGDPV-----EDPDHTE-----
--------------------------EMSNLVNYVLK-KLREDQVQMADYALK-------
-----------------SA--GASIIE--AGTSESYKNNKAKLYWHGISFLNHEMPPDI-
ILQPDVYPGNCWAFPGSQGHTLIKLATKIIPTAVTMEHISEK-VSPSGNISSAPKEFSVY
-----------------GI-----TKKCE-GEEIFLGQFIY-NKTGTTVQ--TFEL--QH
AV--SEY------LLCVKLN-------IFSNWGHPKYTCLYRF-RVHGTPGKHI------
------------------------------------------

------------------------------------------------------------
---------------------------------------------------MSRRSQRLK
---RYS-QGDDDGGSSSSGGSSLVGSQHSLFKDSPIRTLK-RKSS--NVKRLSPAPHLGT
SSNTHTTYYSES--MVSESYVGGPRSSPLAR------SSILHDHQQDSDLYWN-------
---------------------------------------------------EDLLVRRRR
DT--GGTESSKINGLTEN--KVTYDTYGSSSGYSSEDDYTGHL-----------------
---------GEDQYSSGSR---LKKAASRAG--SFLW-----------------------
------MVVTSPGQLFGLCYWWIGTTWYRLT-TNASLLDVFVLTRSVRFP----SLKKL-
LLLLLMLLLLASLAYGA--WYFYPYGLQTLYPAVLSWWAGRASVD-SSKRDVMWESGRPT
AR---IQDEQLVLSQV--HGLERRLEALAAEFSSHWQKEALRLER-LELWQ---------
---------VSHEA-----------TLTLLEG--L--VSRR------E-AVLREDFRVGL
A---------------------N-----RIQRGHPQSINLKGERAKSERLDHRRPLGVRA
RGRNRVTVVACGW----ESTSSTQEALRASML--QELGRLEGQLADLRQELATLTLKQAT
VAEQVEGFPQKIQAVQD-------EVESQFPGWISRFL-LR----D---EAVGTKL-LQR
EELHD-----QLQKLEHKIL-AHLAQERG-----KSAQEAAAGLGVVLRKEGVTGVTEEQ
-----------------------VH----HIVSQALK-RYSEDQIGLVDYALE-------
-----------------SG--GASVIN--TRCSETYETKTALLSLFGIPLWYHSQSPRT-
ILHPDVYPGNCWAFRGPQGFAVVRLSARIRPTAVTLEHVSKS-LLPSSTLLSAPKDFVIL
G-----------------L-----DEETQ-QEGTPMGRFTYESARKTPIQ--TFQL--ED
TQ--STT------YQVVELR-------ILSNWGHPEYTCIYRF-RVHGEPQA--------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MP----------------
------------------------------------------RSR----------NTG--
-----A-SCAPPED-----------LSHCARP--R----R-GNQRGH-------------
------------------------PANRTTEAPSAN--MTWLTC----------L-ACFL
RTQAQQV----------LLNTCRCKLLCQKLM--EKMGLLILCAFG-----------FWM
FSMHLPSKMEVWQDDS---------INGPL----QSLR-MY----QEKVRHHTGEIQDLR
GSMN-------------LLI-AKLQEMQA--------------------------MSDKQ
K-----------------------------MAQKIMK-MIHGDYIEKPDFALK-------
-----------------SI--GASIDF--EHTSATYNHDKARSYWNWIRLWNYAQPPDV-
ILEPNVTPGNCWAFAGDRGQVTIRLAQKVYLSNITLQHIPKT-ISLSGSLDTAPKDFVIY
-----------------GM---E---S-PPREEVFLGAFQF-QP-ENTIQ--MFPL--QN
QP--PRG------FAAVKVK-------ISSNWGNPRFTCLYRV-RVHGSVTPPRDSNLE-
S-----------------------------------------

------------------------------------------------------------
---------------------------------------------------MSRRSQRLT
---RYS-QGDDDGS-SSSGGSSVAGSQSTLFKDSPLRTLK-RKSS--NMKRLSPAPQLGP
SSDAHTSYYSES--LVRESYIGT---AFP------PRSA-LE-E-LHGDADWG-------
---------------------------------------------------EDLRVRRRR
GT--GGSESSRASGLV-GR-KAAEDFLGSSSGYSSEDDYM--------------------
-----GYS-DADQQSSGSR---LWNAVSRAG--SLLW-----------------------
------MVATSPGRLFRLLYWWAGTTWYRLT-TAASLLDVFVLTRR--FS----SLKTF-
LWFLLPLLLLTCLTYGA--WYFYPYGLQTFHPALVSWWAAKD----SRRQDEGWESRDS-
SH---FQAEQRVMSRV--HSLERRLEALAAEFSSNWQKEAMRLER-LELRQGAPGQGG--
------GGGLSHED-----------TLALLEG--L--VSRH------E-AALKEDFRREA
A---------------------A-----RIQEELSA---LRAEHQQDSEDLFKKIVRASQ
ESEARIQQLKSEW----Q--SMTQESFRESSV--KELRRLEDQLAGLQQELAALALKQSL
VADEVGLLPQQIQAVRD-------DVESQFPAWISQFL-AR----G---GGGRVGL-LQR
EEMQA-----QLRELESKIL-THVAEMQG-----KSAREAAASLGMTLQKEGVIGVTEEQ
-----------------------VH----RIVKQALQ-RYSEDRIGLADYALE-------
-----------------SG--GASVIS--TRCSETYETKTALLSLFGIPLWYHSQSPRV-
ILQPDVHPGNCWAFQGPQGFAVVRLSARIRPTAVTLEHVPKA-LSPNSTISSAPKDFAIF
G-----------------F-----DEDLQ-QEGTLLGKFTYDQD-GEPIQ--TFHF--QA
PS--MAT------YQVVELR-------ILTNWGHPEYTCIYRF-R------VHGEPAH--
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MP----------------
--------------R---------------------------SSR----------SPG--
-----DPGAP-LED-----------VALNPRP--R----R-IAQRGRNTSRMVEDTSSNM
N-D-NFLLPV---------RINA-QALGLTQCMLGC--VSWFTC----------F-ACSL
RTQAQQV----------LFNTCRCKLLCQKLM--EKTGILLLCAFG-----------FWM
FSIHLPSKMKVWQVSA---------PQLTG----LTLTSQYHLHSSTHSHQISGEIQDLR
GSMN-------------LLI-AKLQEMEA--------------------------MSDEQ
K-----------------------------VAQKIMK-MIHGDYIEKPDFALK-------
-----------------ST--GASIDF--EHTSATYNHEKAHSYWNWIQLWNYAQPPDV-
ILEPNVTPGNCWAFEGNRGQVTIQLAQKVYLSNLTLQHIPKT-ISPSGSLDTAPKDFVIY
-----------------GM---E---G-SPKEEVFLGAFQF-QP-ENIIQ--MFPL--QN
QP--ARA------FGTVKVK-------ISSNWGNPAFTCLYRV-RVHGSVAPPAEQASPE
PLT---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------QGELDA---LRTQLQADVDKRLGKMAQASQ
EMEARLQELNAEWQRW-H--RSVQEELQGHWQ--RATGELQREVSALRRELAGLRSDQEA
VSKHLEAVLEQIKATRA-------DVEAQMPAWISRFL-AQ----PRQDDSTAGLL-LQR
EDLQA-----ELRALELRIL-AQMREERG-----LAARD---SIGVALRQGGAGGVTEEQ
-----------------------VH----LIVDQALK-RYSEDRVGMVDYALE-------
-----------------S--AGASVIN--TRCSETYETKTALLSLFGIPLWYHSQSPRV-
ILQPDVNPGNCWAFRGSQGFAVIRLSSLIRPTAVTLEHVPKA-LSPQGTIPSAPKDFTVY
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MP----------------
--------------R---------------------------SSR----------SPG--
-----DPGAL-LED-----------VAHNPRP--R----R-IAQRGRNTSRMAEDTSPNM
N-D-NILLPV---------RNND-QALGLTQCMLGC--VSWFTC----------F-ACSL
RTQAQQV----------LFNTCRCKLLCQKLM--EKTGILLLCAFG-----------FWM
FSIHLPSKMKVWQDDS---------INGPL----QSL-RLY----QEKVRHHSGEIQDLR
GSMN-------------QLI-AKLQEMEA--------------------------MSDEQ
K-----------------------------MAQKIMK-MIHGDYIEKPDFALK-------
-----------------SI--GASIDF--EHTSVTYNHEKAHSYWNWIQLWNYAQPPDV-
ILEPNVTPGNCWAFEGDRGQVTIQLAQKVYLSNLTLQHIPKT-ISLSGSLDTAPKDFVIY
-----------------GM---E---G-SPKEEVFLGAFQF-QP-ENIIQ--MFPL--QN
QP--ARA------FSAVKVK-------ISSNWGNPGFTCLYRV-RVHGSVAPPREQPHQN
PYPKRD------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MP----------------
--------------R---------------------------SSR----------SPG--
-----DPGAL-LED-----------VAHNPRP--R----R-IAQRGRNTSRMAEDTSPNM
N-D-NILLPV---------RNND-QALGLTQCMLGC--VSWFTC----------F-ACSL
RTQAQQV----------LFNTCRCKLLCQKLM--EKTGILLLCAFG-----------FWM
FSIHLPSKMKVWQVSA---------PRLTG----LTLTSQYHLHSSIHSHQIGGEIQDLR
GSMN-------------QLI-AKLQEMEA--------------------------MSDEQ
K-----------------------------MAQKIMK-MIHGDYIEKPDFALK-------
-----------------SI--GASIDF--EHTSATYNHEKAHSYWNWIQLWNYAQPPDV-
ILEPNMTPGNCWAFEGDRGQVTIQLAQKVYLSNLTLQHIPKT-ISLSGSLDTAPKDFVIY
-----------------GM---E---G-SPKEEVFLGAFQF-QP-ENIIQ--MFPL--QN
QP--ARA------FGAVKVK-------ISSNWGNPGFTCLYRV-RVHGSVAPPREQPHQN
PYPERD------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------MVTLLLIG-------LGNHMWL
KETEFPQKSSHFYALIA-------EYGSRLYNFQARLR-MP----KEHLELLKD------
-----------------------TRDGLHNYSGD-----TDGG-----EDQNPMGAIDE-
--------------------------EMSNLVNSILK-KLREDQVQMADYALK-------
-----------------SA--GASVIE--AGTSESYKNNKAKLYWHGIGFLTYEMPPDV-
ILQPDVHPGKCWAFPGSQGHALIQLARKITPIAVTMEHISQK-VSPSGNISSAPKEFSVY
-----------------GI-----LKHCE-GEEILLGRFVY-NKTGTTIQ--TFKL--QH
EV--SEP------LLCVKLK-------ILSNWGHPKYTCLYRF-RVHGIPESTPRGSQAD
GRDHRSRICDSSYFLRFITSIGIKMGVGGEPQSGSYLPRKCE

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------MRRSTRS--------------
------------GSVASSDEH---MPNFYSENSNSSDSVPSGDCC--GR-RSPGPGPGEP
QGR--RARGASCGEPTLRPGLPGGTPWAGSSPQEPAPRNHNRE----TARGAAT-VRG-G
A-S---------VSEE---QRSLLATLDLRREMPAL-RATKSF-----------LSLLF-
----QVPRVLLSLVRGVLLG--VCREVCCVRFLF-AASLLSIFLAA----------LSWG
LLHLLPPLENDSKA------------MLTPS--------EY----HERVRSHGQQLQQLQ
AELNK-------------LR-TEVARVRA--------------------------AHSE-
-----------------------------RVAKLVFQ-RLNEDFVQKPDYALS-------
-----------------SV--GATIDL--QKTSHDYEDTKTAYFWNRFSFWNYARPPTV-
ILEPDVFPGNCWAFQGDQGQVAIQLAGRVQLSDITLQHPPPS-VAHTGDASSAPRDFAVF
G-----------------L-----QIDN--ETEVFLGRFTF-DVKKSAIQ--TFHL--QN
DP--PSA------FPKVKIQ-------ILSNWGHPRFTCLYRV-RAHGLRISEGEDSA-T
G--ATGG-----------------------PH----------

------------------------------------------------------------
---------------------------------------------------MSRRSQRLT
---RYS-QDDND-GSSSSGASSVAGSQSTLFKDSPLRTLK-RKSS--NMKRLSPAPQLGP
SSDSHTSYYSES--VVRESFIGSPRAASL------ARSALLE-DRLHSEPYWS-------
---------------------------------------------------GELRGRRRR
GT--GGSEGSKANGLAAES-KASEDFFGSSSGYSSEDDF---------------------
----AGYA-DSEEHGSGSG---LRSAASRAG--SFVW-----------------------
------TLVTFPGRLFGLLYWWVGTTWYRLT-TAASLLDVFVLTRSRHFP---LNLKTF-
LWFLLFLLLLTGLTYGA--WYFYPFGLHTLQPTLASWWAAKE----SRRQPEVWESRDAS
PH---FPAEQRILSRV--HSLERRLEALAAEFSSNWQKEAIRLER-LELRQGAAGHGGGG
GGGGGGGSGLSHED-----------TLSLLEG--L--VSRR------E-AALKEDLRRDT
A---------------------A-----RLQEELAA---LRAEHHQDSEDLFKKIVQASQ
ESEARVQQLKTEW----Q--RMTQEAFQESSM--KELGRLEAQLASLRQELAALTLRQNS
VADEVGLLPQKIQAARA-------DVESQFPDWVSQFL-LR----D---KGARSGL-LRR
DEMHA-----QLQELESKIL-ASVAEMQG-----KSVREAAASLGRTLQKEGVVGVTEEQ
-----------------------VH----RIVKQALQ-RYSEDRIGMVDYALE-------
-----------------SG--GASVIS--TRCSETYETKTALLSLFGIPLWYHSQSPRV-
ILQPDVHPGNCWAFQGPQGFAVVRLSARIRPTAVTLEHVPKA-LSPNSTISSAPKDFAIF
G-----------------F-----DEDLQ-QEGTLLGTFAYDQD-GEPIQ--TFYF--QA
SK--MAT------YQVVELR-------ILTNWGHPEYTCIYRF-RVHGEPAH--------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------ITRGRNACRMAQGSSPNT
S-PDNFLFPV---------N-----APSLIHCMLGC--MXXXXX----------X-XXXX
XXXXXXX----------XXXXXXXXXXXXXXX--XXXXXXXXXXXX-----------FWV
FSMYLPSKMEVWQXXX---------XXXXX----XXXX-MY----QEKVRHHTGEIQDLR
GSMN-------------QLI-TKLQEVEA--------------------------MSDEQ
K-----------------------------MAQKIMK-MIQGDYIEKPDFALK-------
-----------------SI--XXXXXXXXXXXXXXXXXXXX---XXXXXXXXXXXXXXXX
XXXPNMTPGNCWAFAGDRGQVTIRLAQKVFLSNLTLQHIPKT-ISLSGSLDTAPKDFVIY
-----------------GM---E-------GYGGVLGAFQ--------------------
------------------------------------------------------------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MP----------------
--------------R---------------------------PR-----------NPC--
-----N----AASN-----------RLQEYQE--ARSR--XXXXXXXXXXXXXXXXXXXX
X---XXXXXX---------XXXX-XXXXXXXXXXXX--XXXXXX----------X-XXXX
XXXXXXX----------XXXXXXXXXXXXXXX--XXXXXXXXXXXX-----------XXX
XXXXXXXXXXXXXXXX---------XXXXX----XXXXXMY----QEKVQRHAGEIQDLR
GNMS-------------LLI-IRLQMMEA--------------------------LSDEH
K-----------------------------MAQRIMK-LIQGDYIEKPDFALK-------
-----------------SI--GASIDF--EQTSSTYNYNKARSCWNWIRLWNYAXXXXX-
XXXPDVTPGNCWAFSGDRGQVTIRLAQKVFLSNVTLQHIPKT-ISLSGSLDTAPKDFVVY
-----------------GL---E---G-SLKEEVFLGAFQF-QP-ENIIQ--TFPL--Q-
------------------------------------------------------------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------RSLR-RKVT-----TLKH--APTP
RQSAHHSHYSETSSYITRDKLGH--------------TSEL-PETDYDASYWG-------
---------------------------------------------------DNLVRSR-V
GL--ERSYQSKNGVSETQ---LSYDKSTSSSGYSSEEDFTGML-----------------
---------GVMADVQQQNHISVSFSCHLSS--AHCL-----------------------
------SLLHGTGRVFGLLYWWFGTTWYRLT-TSASLLDVFILTRH--YS----MLKKPL
-IILLLLLLLALL--GAGLWHFYPYGLGGLTIIPTSLFSVKHTPKGEGI---PLKQEETR
SQAQSLLSEAEFISRM--ESLERKFHSL-E---------KGLTL----LQQQNMAKPK--
ETEVPRDVGVSREE-----------IFQIFSE--L--SSDR------E-AALMDSIQQQE
A---------------------T-----KA---KNNLRNLREEQQGNLQEMVQKMHNMFK
DVEAEIVQLKTDM----K--SSATDDLNKNLV--EVEGRLSGELLGIKEQLKAVRKTQAD
LSQQVETVPKQIQGVRD-------GVELLFPKWLRTQM-ED----GRTGPLAE--LFLRR
DELQK-----HLVELERKIL-AGIATERN-----EWAARAHTSVDRELQAGGLSGITREE
-----------------------VH----EIVNRAIQ-TYSEDRIGMVDYALE-------
-----------------SS--GASVIN--TRCSETFETKTALLSLFGVPLWYQSQSPRV-
ILQPDLNPGNCWAFRGSQGYAVIRLSSPIHPTAVTIDHIPRS-LSPKATISSAPKDFSVY
G-----------------L-----EEESQ-KEGLLLGNFTY-NQYGKPIQ--TFSI--QG
GD--IPT------YQLVELR-------IQSNWGHPEYTCIYRF-RVHGETEV--------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MP----------------
--------------R---------------------------SSR----------SPQ--
-----GDPCSFLDD-----------VAHNARQ--R----R-ITQRVRNICRTAEDSTANP
G-D-ALLFPV---------RLNT-PTIGLTQSVLGC--MSWLTF----------L-ACFL
RTQAQQV----------LFNTCRCRLLFQKLM--EKTGILVLCAFA-----------FWV
FSIHLPSKMEVWQDDS---------INSPL----QSLR-MY----QEKVRHHTGEIQDLR
GSMN-------------QLI-AKLQGMEA--------------------------MSNEQ
K-----------------------------MTQKILK-MIQGDYIEKPDFALK-------
-----------------SI--GASIDF--EQTSATYNHDKARSYWNWIRLWNYAQPPDV-
ILEPNVTPGNCWAFAGDRGQVTIRLAQKVYLSNVTLQHIPKT-ISLSGSLDTAPKDFVIY
-----------------GM---E---S-SPREEVFLGAFQF-QP-ENTIQ--MFPL--QN
QP--PRA------FGAVKVK-------VSSNWGHPRFTCLYRV-RVHGSVMLPEQHST-P
NPR---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------V--ERTSKSYGGNRWL----SP-FFSSAKPPET-
ILQPDISAGNCWAFQGSRGHVVIRLPEKIWPTAFTIWHISKA-VSPSGEVSTAPREFAVS
G-----------------V-----DED-E-GEA-LLGSFIY-DVDGEIAQ--TFPV--QE
EP--RKA------FRQIKLE-------VRSNWGNKEYTCVYRA-DVHGHPEKK-------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------MDVSF-
SLLPDISPGSCWAFQGSQGHVVIRLPEKIQPRAFTIWHISRA-VSPCGEVSSAPEEFAVS
V-----------------S-----LCL-----------LL--LLEGPRAR--GRAL--PE
MS-----------FWW--------------------------------------------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----TSYYSES--MMSESYLGGSRGLAA------LGTSGL-DDPLDRSIYWG-------
---------------------------------------------------GEFSTRRRR
GT--GDTESSKINGLLES---KTYDTYASSSGYSSEDDYTGHF-----------------
---------YSGQSSSGSG---LRSAASRVG--SFLW-----------------------
------QVLTSPVRFVGWLFSCVGAAWHRLT-GRAPQLARVPLSRC--YG----EEALQA
LYPLPRETFHNPT--SPGAWYFYPYGLSTHSFPAFPWWGAGRLSSSSSP---SFGERDVT
ALDQVNHPKEEVVGGNGPKISQRSFPAV-PASSK----GPGRCTG---GLHGTLPSPP--
QGSLPSQIS--PGL-----------LFLLV----L--AGDGGPLAGAE-FGLAEV-MARH
S---------------------A-----GP---KPLLRGSKGG-----------IRTHFA
RASQ---SHFVVW----R--SSVREDLRGGFQ--QALGELEQEVAGLRRELAGLKADQEA
MGKHVEGLLEQLKALRA-------DVEAQMPAWIGRVL-SQ----PR-----RDGVVLQR
EDLQEEL-----QALEHKIL-AKMQEERR-----LSAREASAGIGVALRPGGAGGVTEEQ
-----------------------VH----LIVDQAGC-FVGCRRSAYPCLPLA-------
-----------------LL--GASVIN--TRCSETYETKTALLSLFGIPLWYQSQSPRV-
ILQPDVNPGNCWAFRGSQGFAVIRLSSPIRPTAVTLEHIPRA-LSPQGIIPSAPKDFSVY
G-----------------L-----KEERD-EEGLLLGHFTY-DQDGNPIQ--TFLL--EG
DA--VGT------FQLVELR-------VLSNWGHPEYTCIYRF-RVHGEPAH--------
------------------------------------------

------------------------------------------------------------
---------------------------------------------------MSRRSQRLT
---RYA-QGDDDGGSSSSGGSSVTGSQGPLFKDSPLRTLK-RKSS--TMKRLSPAPQLGP
SSDSHTSYYSES--VVRESYIGSPRAASL------ARSALLE-DRLRSEPYWS-------
---------------------------------------------------EDLRVRRRR
GT--GGSESSKTNGLAAES-KASEEVFGSSSGYSSEDDF---------------------
----AGYS-DLEQHSSGSR---LRSAISRAG--AFVW-----------------------
------MLLTFPGRLFSLLYWWVGTTWYRLT-TAASLLDVFVLTRSRRFS----SLKPF-
LWFLLLLLLLTGLTYGA--WYFFPFGLQTFHPAVVSWWALKE----DRRQPEVWESRDTS
PH---FQAEQRILSRV--HSLERRLEALAAEFSSNWQKEAIRLER-LELRQGAAGQAG--
------GSGLSHED-----------TLALLEG--L--VSRR------E-AALKEDFRRDT
A---------------------A-----RIQEELAT---LRAEHHQDSEDLFRKIVQASQ
ESEARVQQLKSEW----Q--RMTQEAFRESSM--KELGQLEAQLAGLRQELSTLALKQSS
VADEVDLLPQKIQAVRD-------DVESQFPAWVSQFL-LR----G---GGAHTGL-LQR
EEMHA-----QLQELESKIL-AHVAEMQG-----TSAREAAVSLGRALQKEGMVGVTEEQ
-----------------------VH----RIVKQALQ-RYSEDRIGLVDYALE-------
-----------------SG--GASVIS--TRCSETYETKTALLSLFGIPLWYHSQSPRV-
ILQPDVHPGNCWAFQGPQGFAVVRLSARIRPTAVTLEHVPKA-LSPNSTISSAPKDFAIF
G-----------------L-----DEDLQ-QEGTLLGTFTYDQD-GEPIQ--TFYF--QV
TK--MAP------YQVVELR-------ILTNWGHPEYTCIYRF-RVHGEPTH--------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------------MGR-G
AGPDPQRL-------EPDSH--LAESCSRELGLGPR-RGAV-------------------
--------GFIKVRGLSLPP--FFREVCSIRFLLTAVSLLSLFLAA----------LWWG
LLYLIPPLENEPKE------------MLTLS--------EY----HERVRSQGQQLQQLQ
AELDK-------------LH-KEVSSVRA--------------------------ANSE-
-----------------------------RVAKLVFQ-RLNEDFVRKPDYALS-------
-----------------SV--GASIDL--EKTSHDYEDANTAYFWNRFSFWNYARPPTV-
ILEPDVFPGNCWAFEGDQGQVVIRLPGRVQLSDITLQHPPPS-VAHTGGAKSAPRDFAVY
G-----------------L-----QVDD--ETEVFLGKFTF-NVEKSEIQ--TFHL--QV
CV--SGG------EGAKRMGQQRKTGEKGSPWDSRPWHDPFVS-LE--------------
------------------------------------------

------------------------------------------------------------
---------------------------------------------------MSRRSQRLT
---RYS-QGDDDGS-SSSGGSSVAGSQSTLFKDSPLRTLK-RKSS--NMKRLSPAPQLGP
SSDAHTSYYSES--LVRESW-------FP------PRSS-LE-E-LHGDANWG-------
---------------------------------------------------EDLRVRRRR
GT--GGSESSRASGLV-GR-KATEDFLGSSSGYSSEDDYV--------------------
-----GYS-DVDQQSSGSR---LRSAVSRAG--SLLW-----------------------
------MVATSPGRLFRLLYWWAGTTWYRLT-TAASLLDVFVLTRR--FS----SLKTF-
LWFLLPLLLLTCLTYGA--WYFYPYGLQTFHPALVSWWAAKD----SRRPDEGWEARDSS
PH---FQAEQRVMSRV--HSLERRLEALAAEFSSNWQKEAMRLER-LELRQGAPGQGG--
------GGGLSHED-----------TLALLEG--L--VSRR------E-AALKEDFRRET
A---------------------A-----RIQEELSA---LRAEHQQDSEDLFKKIVRASQ
ESEARIQQLKSEW----Q--SMTQESFQESSV--KELRRLEDQLAGLQQELAALALKQSS
VADEVGLLPQQIQVVRD-------DVESQFPAWISQFL-AR----G---GGGRVGL-LQR
EEMQA-----QLRELESKIL-THVAEMQG-----KSAREAAASLGLTLQKEGVIGVTEEQ
-----------------------VH----HIVKQALQ-RYSEDRIGLADYALE-------
-----------------SG--GASVIS--TRCSETYETKTALLSLFGIPLWYHSQSPRV-
ILQPDVHPGNCWAFQGPQGFAVVRLSARIRPTAVTLEHVPKA-LSPNSTISSAPKDFAIF
G-----------------F-----DEDLQ-QEGTLLGKFTYDQD-GEPIQ--TFHF--QA
PT--MAT------YQVVELR-------ILTNWGHPEYTCIYRF-R------VHGEPAH--
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MP----------------
--------------R---------------------------FPR----------NPG--
-----DPSAPP-ED------------AH-------NPRSRRVTQRGRNTSRMAEDSSYSA
--SDAFLLPV---------RIST-PAISLTQWILGC--MSWFTC----------L-ACFL
RTQAQQV----------LFNTCXXXXXXXXXX---XXXXXXXXXXX-----------FWM
FSMHLPSKMEVWQDDS---------INSPL----KSLR-MY----QEKVRHHTGEIQDLR
GSMN-------------QLI-AKLQEMEA--------------------------MSDEQ
K-----------------------------MTQKIMK-MIQGDYIEKPDFALK-------
-----------------SI--XXXXXX--XXXXXXXXXXXXXXYWNWIRLWNYAKPPDV-
ILEPNMTPGDCWAFAGDRGQVTIRLAQKVYLSNLTLQHIPKT-ISLSGSLDTAPKDFVIY
-----------------GM---E---N-PPREEVFLGAFQF-QP-ENTIQ--TFPL--QN
QP--ART------FGAVKVK-------ISSNWGNPRFTCLYRV-RVHGSVTPPKEQPGQN
PSPQRD------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MP----------------
--------------R---------------------------SSR----------NPR--
-----D-PCILSED-----------MAYNTRP--R-----RGNQRSRNPCRVAEESTARR
--NDGFLLPA---------HVDT-PAVSLTHSVLGY--VSWFTC----------L-ACFL
RTQAQQV----------LFNTCRCKLLCQKLV--EKTVILVLCAFG-----------FWL
FSMHIPSKMEIWQDNS---------INSPL----QSLR-LY----QEKVRHHTGEIQDLR
GSVN-------------QLI-AKLKEMEA--------------------------MSDEQ
K-----------------------------MAQKIMK-MIQGDYIEKPDFALK-------
-----------------SI--GATIDF--EHTSATYNHDKARSYWNWIRLWNYAQPPDV-
ILEPNMTPGNCWAFVGDRGQVTIRLAQKVYLSNLTLQHIPKT-ISLSGSLDTAPKDFIIY
-----------------GM---E---S-SPGEEVFLGAFQF-QP-ENTIQ--MFPL--QN
HQ--PRA------FGAVKVK-------ISSNWGNPRFTCLYRV-RVHGSVAPPTQNPALK
E-----------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------MRRSPRP--------------
------------GSVASPQEH---RLSFYSENSDSSDSVPSRDSS--GH-RFPGQGPGEP
EGR--RDRGSSCGEPALRRRLPRGSSWAGSSRQEPSPGNHNLE----TACGAAT-VRG-G
A-SEPAASPA--VSEE---QRSLLAILDLRREMPAL-RATKSF-----------LSLLF-
----QVPRVLLLLVRDALLG--VCREVCSVHFLS-AASLLSVFLAA----------LSWS
LLHLLPPLENEPKA------------MLSPS--------EH----QERLRSHGQQLQQLQ
AELNK-------------LR-KEVARVRK--------------------------AHSE-
-----------------------------RVAKLVFQ-RLNEDFVQKPDYALS-------
-----------------SV--GATIDL--EKTSHDYEDTNMAYFWNRFSFWNYARPPTV-
ILEPDVFPGNCWAFQGHQGQVVIRLAGRVQLSDITLQHPPPS-VAHTEDASSAPRDFAVF
G-----------------L-----QVDD--KTEVFLGRFTF-DVKKFAIQ--TFHL--QN
DS--PSA------FPKVKIQ-------ILSNWGHPRFTCLYRV-RAHGLRISEGEGSA-T
G--ATRG-----------------------PH----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MP----------------
--------------R---------------------------SSR----------SPG--
-----DPGAP-LED-----------VAHNPRP--R----R-IAQRGRNTSRIVEDTSSNM
N-D-NFLLPV---------RINA-QALGLTQCMLGC--VSWFTC----------F-ACSL
RTQAQQV----------LFNMCRCKLLCQKLM--EKTGILLLCAFG-----------FWM
FSIHLPSKMKVWQDDS---------INGPL----QSL-RLY----QEKVRHHSGEIQDLR
GSMN-------------LLI-AKLQEMEA--------------------------MSDEQ
K-----------------------------VAQKIMK-MIHGDYIEKPDFALK-------
-----------------ST--GASIDF--EHTSATYNHEKAHSYWNWIQLWNYAQPPDV-
ILEPNVTPGNCWAFEGNRGQVTIQLAQKVYLSNLTLQHIPKT-ISPSGSLDTAPKDFVIY
-----------------GM---E---G-SPKEEVFLGAFQF-QP-ESIIQ--MFPL--QN
QP--TRA------FGAVKVK-------ISSNWGNPAFTCLYRV-RVHGSVAPPGEQASPE
PLP---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------LTRSWKII----------MSVVF-
--------------------------------------ILTFFLVG-------FRNHVWL
RETGPPQKSRRFYAVIT-------EYGSRLYNYQARLW-MP----KEQLELLKTESQTLE
HNFREILSLVEQIAVLKALL-RDTRHGQHGQHGGSLHAAGEPP-----GA----PGHAE-
--------------------------ETSNLANYVLK-KLREDQVQMADYALK-------
-----------------SA--GASVIE--AGTSESYKNDKAKLSWHGIGFLNYEMPPDA-
ILQPDVHPGKCWAFPGSRGHALVKLAMKIIPTAVTLEHIPEK-VSPSGSVSSAPKEFSVH
-----------------GI-----SKQCE-GEEIFLGQFLY-NNTGATVQ--TFEL--QH
EV--SES------LLCVKLK-------ILSNWGHMKYTCVYRF-RVHGPGGRPG------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------MRRSARP--------------
------------GSAASPPEN---LPNFYSENSNSSDSVSSGDCS--GY-RSPGPGPGEP
EGR--KTRGSSCGEPALRPGLPGGTSWPGSPRQEPAPRSHNRE----TACGAAT-VRG-G
A-SEPAASPA--VSEE---QGSLLSTLDLRQQMPAP-RATESF-----------LSRLF-
----QVLKVLLALVRDVLLG--VCREVCSVRFLF-TASLLSVFLAA----------LSWG
LLHLLPPLENEFKE------------MLTPS--------AY----HERVRFHGQQLQHLQ
DELNK-------------LR-KEVARVRA--------------------------AHSE-
-----------------------------RVAKLVLQ-QLNEDFVQKPDYALS-------
-----------------SV--GASIDL--EKTSRDYEDTNRAYFWNRFSFWNYARPPTV-
ILEPDVFPGNCWAFEGDQGQVVIRLAGHVQLSDITLQHPPPS-VAHTGDASSAPQDFAVF
G-----------------L-----Q-DD--ETEVFLGKFTF-DVKRSALQ--TFHL--QN
DP--PSA------FPKVKIQ-------ILSNWGHPRFTCLYRV-RAHGSQISEKGEDS--
----VFN-----------------------PH----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------MQRGQRP--------------
------------GSPTSSHNH---APHFYSENSNSSHSVTSGDSN--GR-ESPGPELEQA
EGR--RARGSSCGEPDLSPGVHGGHTRAGSSRPKPAPRSHNGQ----TACGAAT-VRG-G
S-SEPCGSS--SVLEE---QLNRIPNLDLRQDMPPA-PVSKSF-----------LSLLF-
----QVLTVLLSVVGDVLVS--VYREVCSIRFLFTAVSLLSVFLAA----------LWWG
LLYLVPPLENEPKE------------MLTLS--------QY----HQRVHSQSQQLQQLQ
TELNK-------------LN-KEVSSVRA--------------------------AHSE-
-----------------------------RVAKLVFQ-RLNEDFVRKPDYALS-------
-----------------SV--GASIDL--EKTSSDYEDTNTAYFWNRLSFWNYARPPSV-
ILEPDVFPGNCWAFEGDQGQVVIRLPGHVQLSDITLQHPPPT-VAHTGGASSAPRDFAVF
G-----------------L-----QVDD--ETEVFLGKFIF-DVQKSEIQ--TFHL--QN
DP--PSA------FPKVKIQ-------VLSNWGHPRFTCLYRV-RAHGVRISEWAEDNAT
G--VAGG-----------------------PY----------

------------------------------------------------------------
---------------------------------------------------MSRRSQRLT
---RYS-QGDDDGGSSSSGGSSVAGSQSTLFKDSPLRTLK-RKSS--NMKRLSPAPQLGP
SSDAHTSYYSES--LVRESYIGT---AFP------PRSA-LE-E-LHGDADWG-------
---------------------------------------------------EDLRVRRRR
GT--GGSESSRASGLV-GR-KATEDFLGSSSGYSSEDDYM--------------------
-----GYS-DADQQSSGSR---LRNAVSRAG--SLLW-----------------------
------MVVTSPGRLFRLLYWWAGTTWYRLT-TAASLLDVFVLTRR--FS----SLKTF-
LWFLLPLLLLTCLTYGA--WYFYPYGLQTFHPALVSWWAAKD----SRRQDEGWESRDS-
SH---FQAEQRVMSRV--HSLERRLEALAAEFSSNWQKEAMRLER-LELRQGAPGQGG--
------GGGLSHED-----------TLALLEG--L--VSRR------E-AALKEDFRREA
A---------------------A-----HIQEELSA---LRAEHQQDSEDLFKKIVRASQ
ESEARIQQLKSEW----Q--SMTQESFRESSV--KELRRLEDQLAGLQQELAALALKQSL
VADEVGLLPQQIQAVRD-------DVESQFPAWISQFL-AR----G---GGGRMGL-LQR
EEMQT-----QLRELESKIL-THVAEMQG-----KSAREAAASLGVTLQKEGVIGVTEEQ
-----------------------VH----RIVKQALQ-RYSEDRIGLADYALE-------
-----------------SG--GASVIS--TRCSETYETKTALLSLFGIPLWYHSQSPRV-
ILQPDVHPGNCWAFQGPQGFAVVRLSARIRPTAVTLEHVPKA-LSPNSTISSAPKDFAIF
G-----------------F-----DEDLQ-QEGTLLGKFTYDQD-GEPIQ--TFHL--QA
PS--MAT------YQVVELR-------ILTNWGHPEYTCIYRF-R------VHGEPAH--
------------------------------------------

------------------------------------------------------------
---------------------------------------------------MSRRSQRLT
---RYS-QGDDDGS-SSSGGSSVAGSQSTLFKDSPLRTLK-RKSS--NMKRLSPAPQLGP
SSDAHTSYYSES--LVRESYIGT---RFP------PRSS-LE-E-LHGDADWG-------
---------------------------------------------------EDLRVRRRR
GT--GGSESSRASGLM-GR-KATEDFLGSSSGYSSEDDYV--------------------
-----GYS-DADQQSSGSR---LRSAVSRAG--SLLW-----------------------
------MVATSPGRLFRLLYWWAGTTWYRLT-TAASLLDVFVLTRR--FS----SLKTF-
LWFLLPLLLLTCLTYGA--WYFYPYGLQTFHPALVSWWAAKD----SRRQDEGWEARDSS
PH---FQAEQRVMSRV--HSLERRLEALAAEFSSNWQKEAMRLER-LELQQGAPGQGG--
------GGGLSHED-----------TLALLEG--L--VSRR------E-AALKEDFRRET
A---------------------A-----HIQEELSA---LRAEHQQDSEDLFKKIVRASQ
ESEARIQQLKSEW----Q--SMTQESFRESSV--KELRRLEDQLAGLQQELAALALKQSS
VADEVGLLPQQFQAVRD-------DVESQFPAWISQFL-AR----G---GGSRVGL-LQR
EEMQA-----QLRELESKIL-THVAEMQG-----KLAREAAASLGLTLQKEGVIGVTEEQ
-----------------------VH----HIVKQALQ-RYSEDRIGLADYALE-------
-----------------SG--GASVIS--TRCSETYETKTALLSLFGIPLWYHSQSPRV-
ILQPDVHPGNCWAFQGPQGFAVVRLSARIRPTAVTLEHVPKA-LSPNSTISSAPKDFAIF
G-----------------F-----DEDLQ-QEGTLLGKFTYDQD-GEPIQ--TFHF--QA
PT--MAT------YQVVELR-------ILTNWGHPEYTCIYRF-R------VHGEPAH--
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MP----------------
--------------R---------------------------SSR----------SPG--
-----DPGAP-LED-----------VAHHPRP--R----R-IAQRGRNPSRMVEDTSSNM
N-D-NFLLPV---------RINA-QALGLTQCMLGC--VSWFTC----------F-ACSL
RTQAQQV----------LFNTCRCKLLCQKLV--EKTGILLLCAFG-----------FWM
FSIHLPSKMKVWQVSA---------PRLTG----LTLTSQYHLHSSTHSHQISGEIQDLR
GSMN-------------LLI-AKLQKMEA--------------------------MSDEQ
K-----------------------------VAQKIMK-MIHGDYIEKPDFALK-------
-----------------ST--GASIDF--EHTSATYNHEKAHSYWNWIQLWNYAQPPDV-
ILEPNVTPGNCWAFEGNRGQVTIQLAQKVYLSNLTLQHIPKT-ISPSGSLDTAPKDFVIY
-----------------GM---E---G-SPKEEVFLGAFQF-QP-ENIIQ--MFPL--QN
QP--ARA------FGTVKVK-------ISSNWGNPAFTCLYRV-RVHGSVAPPGEQASPE
PLPERD------------------------------------

------------------------------------------------------------
-----------------------MITEGLQH--ADTFRILSSGGESPFYLVMSRRSQRLT
---RYS-QGDDDGGSS-SGGSSVMGSQSTLFKDSPLRTLK-RKSG--NTKRLSPAPQLGP
SSDTHTSYYSES--VVRESYFGSPRAASL------ARSSILD-DQLHSDPYWG-------
---------------------------------------------------EDLRVRRRR
GT--GGTESSKLNGLS-EN-KGSEDFLGSSSGYSSEDDYA--------------------
-----GYS-ETDHRGSGSR---LRNAASWAA--SFFW-----------------------
------MVVTSPGRLFGLLYWWVGTTWYRLT-TAASLLDVFVLT--RRFS----SVKTF-
LWFLLLLLLLTGLTYGA--WYFYPYGLQTFHPAMVSWWAAKG----GSRQHDVRESRDF-
-----QLAEQRILSRV--HSLERRLEALAADFSSNWQKEAVRLER-LELRQGAAGGG---
-----GHVGLSHED-----------TLALLEG--L--VSRR------E-AALKEDFRRDT
A---------------------A-----RIQEELVT---LRAEHQQDSEDLFKKIVQASQ
ESEARLQELKSEW----Q--RMTQESFRENSM--KELGRLEGQLAGLRQELAALSLKQSS
VADQVGLLPQQLQAVRD-------DVESRFPAWISQFL-LR----G---GGARNGL-LQQ
EDMQV-----QLRELEGRIL-AHVAEMRG-----ESAREAAASLGLTLQREGVIGVTEEQ
-----------------------VQ----RIVNQALK-RYSEDRIGMVDYALE-------
-----------------SG--GASVIS--TRCSETYETKTALLSLFGIPLWYHSQSPRV-
ILQPDVHPGNCWAFQGPQGFAVVRLSARIRPTAVTLEHVPKS-LSPNSTISSAPKDFAIF
G-----------------F-----DEDAQ-QEGTLLGQFTYDQD-GEPIQ--TFYF--QD
TK--MAT------YQVVELR-------ILTNWGHPEYTCIYRF-RVHGEPTH--------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------MDVSF-
SLLPDISPGSCWAFQGSQGHVVIRLPEKIQPRAFTIWHISRA-VSPCGEVSSAPEEFAVS
V-----------------S-----LCL-----------LL--LLEGPRAR--GRAL--PE
MS-----------FWW--------------------------------------------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MP----------------
--------------R---------------------------SSR----------SPG--
-----DPGAP-LED-----------VAHNPRP--R----R-IAQRGRNTSRMVEDTSSNM
N-D-NFLLPV---------RINA-QALGLTQCMLGC--VSWFTC----------F-ACSL
RTQAQQV----------LFNTCRCKLLCQKLM--EKTGILLLCAFG-----------FWM
FSIHLPSKMKVWQDDS---------INGPL----QSL-RLY----QEKVRHHSGEIQDLR
GSMN-------------LLI-AKLQEMEA--------------------------MSDEQ
K-----------------------------VAQKIMK-MIHGDYIEKPDFALK-------
-----------------ST--GASIDF--EHTSATYNHEKAHSYWNWIQLWNYAQPPDV-
ILEPNVTPGNCWAFEGNRGQVTIQLAQKVYLSNLTLQHIPKT-ISPSGSLDTAPKDFVIY
-----------------GM---E---G-SPKEEVFLGAFQF-QP-ESIIQ--MFPL--QN
QP--ARA------FGAVKVK-------ISSNWGNPAFTCLYRV-RVHGSVS----KPHQN
PYPERD------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
MLR---RSERNRINLKSP-------------SSE----SKERSK------ATMSPKPT--
SGKEK-----------------------------------------------------LE
T---------------------A-----QP---PITLQGTRRI-----------KHS---
-----------------N--PYVTKDIRKGES-------MEIEVASTSR-----------
-NNNFDCLYEFVFLFAV-------FAFVLLLIYIR----SQ----LISCILLEQKMRQQN
TD-MTLKEISRMKDRFQEIL-NDVSEQKR-----T----------------------QMT
---------------------K-MM---VQEIKNELK-KWEEDNVQVKDYALY-------
-----------------SL--GATIIK--DKTSQSLKSDNLHWSFLGILSWPYTSCPEE-
ILKPDVYPGKCWTFPGSQGQVLIKLSAKIIPVAVTLQHISKT-ISPSKNYSSAPRDFSVF
V-----------------S-----KWHLLASVGEMLFFFIYNNWEKSLIKISLPCL--QN
DD--TSR------FQFIQLR-------ILSNWGNEKYTSVYRF-QVHQELPVQLRS----
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------LTWLWKII----------LSVMC-
--------------------------------------VLTFLLVG-------LQNHQWL
QETVIPQKSRQLYDVFA-------EYGTRLCRYQARFR-MP----REQLELLKKESQTLE
NNFREILFLIEQMDMLKALL-RDMKDGMYDDS---GSGPRDVT-----QDQDSIELPDE-
--------------------------EMLRLVHYVLK-KLREDQVQMADYALK-------
-----------------SA--GAFIVE--SETSESYTNNKSKLYWHGIGFLNHAMPPDV-
ILQPDVHPGKCWAFSGSQGQILIRLARKIIPISVTMEHISEK-VSPSGNISSAPQAFSVH
-----------------GL-----KRRCE-GEEIFLGQFIY-NKTEATVQ--TFHL--QH
EI--SEP------LLCVRLK-------ILSNWGHPRYTCLYRF-RVHGIPSDHT------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------MRRSPHP--------------
------------GSAAAPHKH---TSNFYSDH-NSSESAISGDSS--WH-RSIGPGPVEP
EGR--RARGSSGGEPALSTRVPGGTTWAGSSQQKPEPRSHQGQ----TACSAAI-VRG-G
A-SEPAGTPV--VSEE---PLDLLPAVDLRQEVPPP-QVSKRF-----------LXXXX-
----XXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXX----------XXXX
XXXXXXXXXXEPKE------------MLTLS--------EY----HERVRSHGQQLQQLQ
TELDK-------------LH-KEMSSVRA--------------------------ANSE-
-----------------------------RVAKLVFQ-RLNEDFVQKPDYALS-------
-----------------SV--GASIDL--EKTSSDYEDADSAYFWNRFSFWNYARPPTV-
ILEPDVFPGNCWAFEGDQGQVVIRLPGHIQLSDITLQHPPPS-VVHTEGANSAPRDFAVY
G-----------------L-----QVDD--ETEVFLGKFTF-DVEKSEIQ--TFHL--QN
DP--PAA------FPKVKIQ-------ILSNWGHPRFTCLYRV-RAHGQPISEGSEDNTQ
------G-----------------------PH----------

------------------------------------------------------------
---------------------------------------------------MSRRSQRLT
---RYS-QGDDDGS-SSSGGSSVAGSQSTLFKDSPLRTLK-RKSS--NMKRLSPAPQLGP
SSDAHTSYYSES--LVRESW-------FP------PRSS-LE-E-LHGDANWG-------
---------------------------------------------------EDLRVRRRR
GT--GGSESSRASGLV-GR-KATEDFLGSSSGYSSEDDYV--------------------
-----GYS-DVDQQSSGSR---LRSAVSRAG--SLLW-----------------------
------MVATSPGRLFRLLYWWAGTTWYRLT-TAASLLDVFVLTRR--FS----SLKTF-
LWFLLPLLLLTCLTYGA--WYFYPYGLQTFHPALVSWWAAKD----SRRPDEGWEARDSS
PH---FQAEQRVMSRV--HSLERRLEALAAEFSSNWQKEAMRLER-LELRQGAPGQGG--
------GGGLSHED-----------TLALLEG--L--VSRR------E-AALKEDFRRET
A---------------------A-----RIQEELSA---LRAEHQQDSEDLFKKIVRASQ
ESEARIQQLKSEW----Q--SMTQESFRESSV--KELRRLEDQLAGLQQELAALALKQSS
VADEVGLLPQQIQAMRD-------DVESQFPAWISQFL-AR----G---GGGRVGL-LQR
EEMQA-----QLRELESKIL-THVAEMQG-----KSAREAAASLGLTLQKEGVIGVTEEQ
-----------------------VH----HIVKQALQ-RYSEDRIGLADYALE-------
-----------------SG--GASVIS--TRCSETYETKTALLSLFGIPLWYHSQSPRV-
ILQPDVHPGNCWAFQGPQGFAVVRLSARIRPTAVTLEHVPKA-LSPNSTISSAPKDFAIF
G-----------------F-----DEDLQ-QEGTLLGKFTYDQD-GEPIQ--TFHF--QA
PT--MAT------YQVVELR-------ILTNWGHPEYTCIYRF-R------VHGEPAH--
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------LTRSWKTV----------TSVVF-
--------------------------------------ILTFLLLGF-------RNHMRL
KEKEFPQKSRQFYAVI-------AEYGSQLYNYQARLR-MP----KEQLELLKKESQTLE
NNLREILFLIEEIDVLKALL-RDIRDGLH-SY--SWTADG---------------DSAEG
---------------------WDHTEEMSNLVNYVLK-KLRGDQVQMADYALKSAXXXXX
XXXXXXXXXXXXXXXXXXX--XXXXXX--XX--------XX----XXXXX-X--XXXXX-
-X-XXXXXXXX---X----XXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXX
G-----------------V-----SKQCE-GEEIFLGQFIY-NKTGTTVQ--TFAL--QH
EV--PEF------LLCMKLK-------IFSNWGHPKYTCLYRF-RVHGTPRDDT------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------MSGRTKARRAARFFRGGTE----EASSSAT----GNVLPSEH---
------------------------------------------------------------
E---------------------N-----PD---PNRRTRSRKTV----------LSMIL-
--------------------------------------ALTFLVVG-------LRSHQWL
KEIELPQKSRQVYAILA-------EYGSRIYNYQARLR-MP----KEQLELLKKESQTLE
SNFRDILFLIEQIDVLKALL-RDVKDGAYNQ---SWSAHGDPA-----GPQDAT----E-
--------------------------EMTNLVNYVLK-KLREDQVQMADYALK-------
-----------------SA--GASIIE--AGTSESYKNHKAKLYWHGIGFLNYEMPPDI-
ILQPDVYPGKCWAFPGSQGHTLIKLARKIIPTAVTMEHISEK-VSPSGNISSAPKEFSVY
-----------------GI-----MKKCE-GEETFLGQFMY-NKTGTTVQ--TFKL--KV
MT--ALG------NGKI-------------------------------------------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MP----------------
--------------R---------------------------SSR----------GPA--
-----DPGAL-LED-----------VASNRRP--R----R-IVQRGQNASRMAEDPSSNM
N-D-AFLLPV---------RINA-QALGLTQCMLGC--MSWVSC----------L-AFFL
RTQAQHV----------LFGTCRCKLLCQKLM--EKTGILLLCAFG-----------FWM
FSIHLPSKMTVWQDDS---------ITSPL----QSLR-LY----QEKVRHHSGEIQDLR
GSMN-------------LLI-AKLQEMEA--------------------------MSDEQ
K-----------------------------MAHKIMK-MIQGDYIEKPDFALK-------
-----------------ST--GASVDF--EHTSATYNHDKAHSYWNWIRLWNYAQPPDV-
ILEPNVTPGNCWAFEGDRGQVTIRLAQKIYLSNLTLQHIPKT-ISLSGSLDTAPKDFVVY
-----------------GM---E---S-SPREEVFLGAFQF-QP-ENIIQ--MFPL--QN
QP--ARA------FGEVKVK-------ISSNWGNPSFTCLYRV-RVHGSVASPREQPHQN
PYPERD------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------MRRSPRP--------------
------------GSAASSHNH---TPNFYSENSNSSHSATSGDSN--GR-RSAGPELGEP
EGR--RARGSSCGEPALSSGVPGGDTWAGSSRPKLAPRSHNGQ----TACGAAT-VRG-G
A-SEPSGSP--AVLEE---QLNLLPILDLRQEMPPP-PVSKSF-----------LSLFF-
----QVLSVFLSLVADGLVC--VYREICSIRFLFTAVSLLSIFLAA----------LWWG
LLYLIPPLENEPKE------------MLTLS--------QY----HHRVHSQGQQLQQLQ
AELSK-------------LH-KEVTSVRA--------------------------AHSE-
-----------------------------RVAKLVFQ-RLNEDFVRKPDYALS-------
-----------------SV--GASIDL--EKTSSDYEDRNTAYFWNRLSFWNYARPPSV-
ILEPDVFPGNCWAFEGEQGQVVIRLPGHVQLSDITLQHPPPT-VAHTGGASSAPRDFAVF
G-----------------L-----QADDD-ETEVFLGKFIF-EVQKSEIQ--TFHL--QN
DP--PSA------FPKVKIQ-------ILSNWGHPRFTCLYRV-RAHGVRISESAEDNAM
G--VTGG-----------------------PH----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------V--ERTSKSYGGNRWL----SP-FFSSAKPPET-
ILQPDISAGNCWAFQGSRGHVVIRLPEKIWPTAFTIWHISKA-VSPSGEVSTAPREFAVS
G-----------------V-----DED-E-GEA-LLGSFIY-DVDGEIAQ--TFPV--QE
EP--RKA------FRQIKLE-------VRSNWGNKEYTCVYRA-DVHGHPEKK-------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------MSGKAKARRAAMFFRGCSE----DASSSTS----GNTLLSED---
------------------------------------------------------------
E---------------------N-----PD---ANGVTRSWKII----------LRTMF-
--------------------------------------TLTFLLVG-------LLSHQWL
KETEVPQKSRQLYAIIA-------EYGSRLYKYQARLR-MP----KEQLELLKKESQTLE
NNFRKILLLIEQIDVLKALL-RDMKDGMDNNH--SWNTHGDPV-----EDPDHTE-----
--------------------------EMSNLVNYVLK-KLREDQVQMADYALK-------
-----------------SA--GASIIE--AGTSESYKNNKAKLYWHGIGFLNHEMPPDI-
ILQPEVYPGKCWAFPGSQGHTLIRLATKIIPTAVTMEHISEK-VSPSGNISSAPKEFSVY
-----------------GI-----TKKCE-GEEIFLGQFIY-NKTGTTIQ--TFEL--QH
AV--SEY------LLCVKLN-------IFSNWGHPKYTCLYRF-RVHGTPGKHI------
------------------------------------------

------------------------------------------------------------
-----------------------------------------------------RRSQRLS
---RYS-QGDDDGGSSSSGGSSVMGSQSSLFKDSPLRTLKR-KS---NVKRLSPAPQLGP
ASDTHTSYYSES--VVRESGPP-------------PRSALLE---LHSDTCWXXXXXXXX
XXXXXXXXX--------------------------------------------------X
XX---XXXXXXXXXX------XXXX----------------------------XXXXXXX
XXXXXXYSAELDQRASGSN----GRAASRAG--SFVW-----------------------
------TVATSPGRLLGLLYWWVGTTWYRLT-TAASLLDVFVLTXXXXXXX---------
XXXXXXXXXXXXXXXXXXAWYVYPFGLQMVQPAMVSWWAARG----HSKPQEVWESRDSA
LH---LQTEQRILSRV--HSLERRLEAVASEFSSTWQKEALRLER-LELRQGSASQGG--
----SQGGSLSHED-----------TLRLLEG--I--VNRR------E-AALKEDFRRDM
A---------------------T-----HIQEELAA---LRAESQQDVEDLFKKIVQASQ
ESEGRLQQLKSEWQXX-XX---XXXXXXXXXX--XXXXXXX--XXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXX-------XVESQFPAWVTQFL-VR----G---GGARSGL-LQR
EEIDT-----RLQQLEGRIL-AHVAETQG-----KSVKEAAASLGLALQKDGVIGVTEEX
-----------------------XX----XXXXXXXX-XXXXXXXXXXXXXXX-------
-----------------XX--XASVIS--TRCSETYETKTALLSLFGIPLWYHSQSPRV-
ILQPDVHPGNCWAFQGPQGFAVVRLSARIRPTAVTLEHVPKS-LSPNSTISSAPKDFAVF
X-----------------X-----XXXXX-XXXXXXXXXXXXXX-XXXXX--XXXX--XD
PK--MAA------FQVVELR-------ILTNWGHPEYTCIYRF-RVHGEPTH--------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MP----------------
--------------R---------------------------SSR----------NPR--
-----D-PCILSED-----------MAYNTRP--R-----RGNQRSRNPCRVAEESTARR
--NDGFLLPA---------HVDT-PAVSLTHSVLGY--VSWFTC----------L-ACFL
RTQAQQV----------LFNTCRCKLLCQKLV--EKTVILVLCAFG-----------FWL
FSMHIPSKMEIWQDNS---------INSPL----QSLR-LY----QEKVRHHTGEIQDLR
GSVN-------------QLI-AKLKEMEA--------------------------MSDEQ
K-----------------------------MAQKIMK-MIQGDYIEKPDFALK-------
-----------------SI--GATIDF--EHTSATYNHDKARSYWNWIRLWNYAQPPDV-
ILEPNMTPGNCWAFVGDRGQVTIRLAQKVYLSNLTLQHIPKT-ISLSGSLDTAPKDFIIY
-----------------GM---E---S-SPGEEVFLGAFQF-QP-ENTIQ--MFPL--QN
HQ--PRA------FGAVKVK-------ISSNWGNPRFTCLYRV-RVHGSVAPPTQNPALK
E-----------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------MRRSPHP--------------
------------GSATSPHKH---TPNFYSDDSHSSMSATSGESS--GP-RSTGPGPVEP
DGR--KARGSSCGEPALSSGVPGGTTWDGSSPQKLAPQSHSGT-----AGGAAT-VRG-G
A-SEPTGSSI--VSQE---HFDLLSTMPEMQEMTPP-RLSKSL-----------LSSLL-
----QVLSVLF-FLGDMLVS--VYRK-SSFRFLVTVLSLLGVFLAV----------FWCG
LLYLIPPLDNEPKE------------ILTLT--------QY----HERVRSQGQQLEQLQ
AELDK-------------LH-KEVSSVRA--------------------------ANSE-
-----------------------------RVAELVFQ-RLHEDFVRKPDYALS-------
-----------------SV--GASIDL--EKTSQDYVDTDTGYFWNHFNLWNYARPPTV-
ILEPDVFPGNCWAFEGDQGQVVIRLPGRVQLSDITLQHPPHS-VAHTGGADSAPRNFTVY
G-----------------I-----EADD--ETEVFLGNFTF-EVEKSEIQ--TFHL--QN
DP--PAA------FPKVKIQ-------ILSNWGHPRFTCLYRV-RAHGLKTTEETGDSAP
G--ELH------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MP----------------
--------------R---------------------------SSR----------SPG--
-----DPGAP-LED-----------VAHHPRP--R----R-IAQRGRNPSRMVEDTSSNM
N-D-NFLLPV---------RINA-QALGLTQCMLGC--VSWFTC----------F-ACSL
RTQAQQV----------LFNTCRCKLLCQKLV--EKTGILLLCAFG-----------FWM
FSIHLPSKMKVWQDDS---------INGPL----QSL-RLY----QEKVRHHSGEIQDLR
GSMN-------------LLI-AKLQKMEA--------------------------MSDEQ
K-----------------------------VAQKIMK-MIHGDYIEKPDFALK-------
-----------------ST--GASIDF--EHTSATYNHEKAHSYWNWIQLWNYAQPPDV-
ILEPNVTPGNCWAFEGNRGQVTIQLAQKVYLSNLTLQHIPKT-ISPSGSLDTAPKDFVIY
-----------------GM---E---G-SPKEEVFLGAFQF-QP-ENIIQ--MFPL--QN
QP--ARA------FSTVKVK-------ISSNWGNPAFTCLYRV-RVHGSVAPPREQASPE
PLPERD------------------------------------

------------------------------------------------------------
---------------------------------------------------MSRRSQRLT
---RYS-QDDNDGGSSSSGASSVAGSQGTVFKDSPLRTLK-RKSS--NMKHLSPAPQLGP
SSDSHTSYYSES--VVRESYIGSPRAVSL------ARSALLD-DHLHSEPYWS-------
---------------------------------------------------GDLRGRRRR
GT--GGSESSKANGLTAES-KASEDFFGSSSGYSSEDDL---------------------
----AGYT-DSDQHSSGSG---LRSAASRAG--SFVW-----------------------
------TLVTFPGRLFGLLYWWIGTTWYRLT-TAASLLDVFVLTRSRHFS---LNLKSF-
LWFLLLLLLLTGLTYGA--WHFYPLGLQTLQPAVVSWWAAKE----SRKQPEVWESS-AS
QH---FQAEQRILSRV--HSLERRLEALAADFSSNWQKEAIRLER-LELRQGAAGHGG--
------GSSLSHED-----------ALSLLEG--L--VSRR------E-ATLKEDLRRDT
V---------------------A-----HIQEELAT---LRAEHHQDSEDLFKKIVQASQ
ESEARVQQLKTEW----K--SMTQEAFQESSV--KELGRLEAQLASLRQELAALTLKQNS
VADEVGLLPQKIQAARA-------DVESQFPDWIRQFL-LG----D---RGARSGL-LQR
DEMHA-----QLQELENKIL-TKMAEMQG-----KSAREAAASLGQILQKEGIVGVTEEQ
-----------------------VH----RIVKQALQ-RYSEDRIGMVDYALE-------
-----------------SG--GASVIS--TRCSETYETKTALLSLFGIPLWYHSQSPRV-
ILQPDVHPGNCWAFQGPQGFAVVRLSARIRPTAVTLEHVPKA-LSPNSTISSAPKDFAIF
G-----------------F-----DEDLQ-QEGTLLGTFAYDQD-GEPIQ--TFYF--QA
SK--MAT------YQVVELR-------ILTNWGHPEYTCIYRF-RVHGEPAH--------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MP----------------
--------------R---------------------------SSR----------NPG--
-----DPGAL-SND-----------HVHSARD--ARPR--RTTHRGRYTSRMTEEPSPNM
N-PDTFLLPA---------QISA---PGLSQCMLGF--LSWLTC----------L-ACFL
RTRAHLV----------LLNNCXXXXXXXXXX--XXXXXXXXXXXX-----------FWI
CSVHLPAKLKVWQDDK---------INDPL----KNLR-IY----QEKVQHHTGEIQDLR
GSMN-------------QLI-ARQE--MK--------------------------MSDEQ
R-----------------------------MAQKIMK-VIQGDYIEKPDFALK-------
-----------------SI--XXXXXXXXXXXXXXXXXXXX---XXXXXXXXXXXXXXXX
XXXPNMTPGNCWAFAGNRGQVTIRLAQKIYLSNLTLQHIPQT-ISLSSSLDTAPKDFVIY
-----------------GM---E---G-TPKEEVFLGAFQF-QP-ENILQ--MFPL--QN
EP--ARP------FGAVKVK-------ISSNWGNPHFTCLYRV-RVHGSVAPPREDRHSP
YSRH--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------MRQSPRP--------------
------------CSTVSPHKH---TPYFYSDNSNRSVSVTSGDTS--GH-QSAGPGPGEP
EGR--RARGSSCGEPALSAGAPGGATWSGSSRQKPAPRSHNGQ----TACGAAT-VRG-G
A-SEPAESPV--ISEE---QLDLLPSLDLRQEMPPP-RVSKSF-----------LSLLI-
----QVLSVLLSLVGDALVS--VYXXXXXXXXXXXXXXXXXXXXXX----------LWWG
LLYLAPPLENEPKE------------MLTLS--------EY----HERVRSQGQQLQQLQ
AELDK-------------LH-KEVSSVRA--------------------------ANSE-
-----------------------------RVAKLVFQ-RLNEDFVRKPDYALS-------
-----------------SV--GASIDL--EKTSHDYEDTNTAYFWNRFNFWNYARPPTV-
ILEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXX
G-----------------L-----QVDD--ETEVFLGKFTF-DVEKSEIQ--TFHL--QN
DP--PAA------FPKVKIQ-------ILSNWGHPRFTCLYRV-RAHGVRTSEVAEDSAQ
G--SH-------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------MRPPEV-
ILEPDNHPGNCWPFPGSQGHVFIKLPVAVFPTAVTINHGVPAAAYHADSISSAPKDFAVY
G-----------------L-----QEEDD-EKGTLLGEFIF-MPGQAPGQ--TFQL--KN
EH--SAF------IKYVRLQ-------VLSNWGHPEYTCVYQF-RLHGDP----------
--APD-----------------GD-ARGKLS---A-------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MP----------------
--------------Q---------------------------FSR----------STR--
-----NSGTH----------------PEDARP--R----R-ATQRGRNTCRTAGDPFPNM
N-D-TFLLPL---------RINT-QALGLTQCVLGC--LSWLTC----------M-AYFL
RSQTQHI----------LFNNSRCKLLCQKIL--EKMGVLVLCAFG-----------FWM
FCIHAPSKMEVWQDDS---------VNSPL----QSLS-LY-----QKVRHHSGEIQDLR
GSIN-------------LVI-AKLQEMEA--------------------------MSDEQ
K-----------------------------MTQKIMR-MIQGDYIEKPDFALK-------
-----------------SI--GASIDF--AHTSATFNHDKARSYWNWIRLWNYAQPPDV-
ILEPNMTPGSCWAFAGDRGQVTVRLAQKVFLSNITLQHIPRT-ISLSGSLDTAPKDFVVY
-----------------GM---E---N-SPKEEAFLGAFQF-QP-ENTIQ--MFPL--QN
RL--NRA------FGAVKVK-------ISSNWGNPRFTCLYRV-RVHGSVTPPGEQPK--
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------LTRSWKVI----------LSIML-
--------------------------------------TLTFLLVG-------FRNHQWL
KETQFPQKYRQLYAVVA-------EYGTRLYDYQARMR-MP----RGQLELLKKESQALE
NNFREILLLIEQMDLLRALL-RDMKDGADHDS---GSRPGDVT-----QDQNGAEVPEE-
--------------------------EMFTLVNYVLK-KLREDQVQMADYALK-------
-----------------SA--GASIVE--SETSESYTNNNTKLYWHGIGLLNHE------
---PDVHPGKCWAFPGSQGHILIRLARKIIPMSVTMEHISEK-VSPSRNTSSAPKEFSVH
-----------------GL-----MKRCE-GQEIFLGQFVY-NKTETTIQ--TFDL--QH
EI--SES------LLCVRLK-------ILSNWGHPNYTCLYRF-RVHGIPRDHT------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------MRRSSRP--------------
------------GSASSSRKH---TPNFFSENSSVSIT--SEDSN--GL-RSAGPGPGDP
EGR--GARGPSCGEPALSAGVPGGTTWAGSSRQKPAPRSHNWQ----TAC-GAA-TVR-G
GASEPTGSPA--VSEE---PLDLLPTLDLRQEMPPS-RVFKSF-----------LSLLF-
----QVLSVLLSLAGDVLVS--MYREVCSIRFLFTAVSLLSLFLAA----------IWLG
LLYLVSPLENPTPR-R---------PPPTSS--------EY----HERVRSQGQQLQQLQ
AELDK-------------LH-KEVSTVRA--------------------------ANSE-
-----------------------------RVAKLVFQ-RLNEDFVRKPDYALS-------
-----------------SV--GASIDL--QKTSHDYADRNTAYFWNRFSFWNYARPPTV-
ILEPHVFPGNCWAFEGDQGQVVIQLPGRVQLSDITLQHPPPS-VEHTGGANSAPRDFAVF
G-----------------L-----QVDD--ETEVFLGKFTF-DVEKSEIQ--TFHL--QN
DP--PAA------FPKVKIQ-------ILSNWGHPRFTCLYRV-RAHGVRTSEGAEGSAT
G--GPH------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------MRRNPRT--------------
------------GSAASPRKH---TPNFYSDNSNSSVSVTSEDSN--GH-RSAGPGPGEA
EGR--RARGSSCGEPALSVGVPGGTTWAGSSRQKPAPRSYNGQ----TACGAAT-VRG-G
A-SEPAESPV--VSEE---QLDLLSTLDLRQEMPTP-RVSKSF-----------LSLLF-
----QVLSVLLSLVGDVLVS--VYREVCSIRFLLTAVSLLSLFLAA----------LWLG
LLYLVPPLENEPKE------------MLSLS--------EY----HERVRSQGQQLQQLQ
AELDK-------------LY-KEVSSVRA--------------------------ANSE-
-----------------------------RVATLVFQ-RLNEDFVRKPDYALS-------
-----------------SV--GASIDL--EKTSHDYEDTNTAYFWNRFSFWNYARPPTV-
ILEPDVFPGNCWAFEGDQGQVVIRLPGRVQLSDITLQHPPPS-VAHTGGANSAPRDFAVF
G-----------------L-----QVDD--ETEVFLGKFTF-DVEISEIQ--TFHL--QN
DP--PAA------FPKVKIQ-------ILSNWGHPRFTCLYRV-RAHGVRTSEGAGDNAT
G--ATGG-----------------------PH----------

------------------------------------------------------------
---------------------------------------------------MSRRSQRLT
---RYS-QGDDDGS-SSSGGSSVMGSQSTLFKDSPLRTLK-RKSS--NTKRLSPAPQLGP
SSDAHTSYYSES--MVQESYIGSPRAASL------PLI----------LPCTG-------
---------------------------------------------------EDLRVRRRR
GT--GGTESSKANGLT-EG-KVSEDFLGSSSGYSSEDDYVDSI-----------------
-------P-QGSTQSSGSR---LRSAVSRAG--SFLW-----------------------
------LVVTSPGRLFGLLYWWVGTTWYRLT-TAASLLDVFVLTRR--FS----SLKTF-
LWFLLLLLLLTCLTYGA--WYFYPYGLQTFHPAVVSWWAAKD----SRKQHEAWDSRDSP
PH---FKAEQRILSQV--HSLERRLETLAAEFSSNWQKEAMRLER-LELRQGASGQGG--
------GGGLSHED-----------TLALLEG--L--VSRR------E-AALKEDFRRDT
T---------------------A-----RIQEELAA---LRAEHQHDAEDLFKKIVQASQ
ESEARIQQLKSEW----Q--RMTQEAIQESSE--KELRRLEDQLAGLRQELAALALKQSS
VAGEVGLLPQQIQAVRD-------DVESQFPAWISQFL-LR----G---GGTHAGL-LQR
EEVQT-----QLQELESRIF-AHVTEMQG-----RSARETATSLGLTLQKEGMVGVTEEQ
-----------------------VH----RIVKQALQ-RYSEDRIGMVDYALE-------
-----------------SG--GASVIS--TRCSETYETKTALLSLFGIPLWYHSQSPRV-
ILQPDVHPGNCWAFQGPQGFAVVRLSARIRPTAVTLEHVPKA-LSPNSTISSAPKDFAIF
G-----------------F-----DEDLQ-QEGTLLGKFTYDQD-GEPIQ--TFHF--QA
PK--MAT------YQVVELR-------ILTNWGHPEYTCIYRF-RVHGEPTH--------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------MAYMRPPEV-
ILEPDNHPGNCWPFPGSQGHVFIKLPVAVFPTAVTINHGIPAAAYHADSISSAPKDFAVY
G-----------------L-----QEEDD-EKGTLLGEFIF-TPGQAPGQ--TFQL--KN
EH--SGF------IKYVRLQ-------VLSNWGHPDYTCVYQF-RLHGDP----------
--SMM-----------------VM-LGGKLS---A-------

------------------------------------------------------------
---------------------------------------------------MSRRSQRLT
---RYS-QDDND-GSSSSGASSVAGSQSTLFKDSPLRTLK-RKSS--NMKRLSPAPQLGP
SSDSHTSYYSES--VVRESYIGSPRAASL------ARSALLD-DRLHSEPYWS-------
---------------------------------------------------GDLRGRRRR
GT--GGSESSKANGLTTES-KVSEDFFGSSSGYSSEDDF---------------------
----AGYM-ESDQHGSGSG---LRSAASRAG--SFVW-----------------------
------TLVTFPGRLFGLLYWWVGTTWYRLT-TAASLLDVFVLTRSRHFS---LNLKTF-
LWFLLFLLLLTVLTYGA--WYFYPFGLHTLQPTLASWWAAKE----SKRQPEVWESRDAS
PH---FQAEQRILSRV--YSLERRLEALAAEFSSNWQKEAIRLER-LELRQGATGHGG--
------GSGLSHED-----------TLTLLEG--L--VSRR------E-AALKEDLRRDT
M---------------------S-----RIQEELAT---LRAEHHQDSEDLFRKIVQASQ
ESEAHVQQLKTEW----Q--RMTQEAFQESSV--KELGQLEAQLASLRQELAALTLRQNS
VADEVGLLPQKIQAARA-------DVESQFPDWVSRFL-LR----D---KGASSGL-LQR
DELHA-----QLQELESKIL-ASMAEMQG-----KSAREAAASLGQTLQKEGVVGVTEEQ
-----------------------VH----QIVKQALQ-RYSEDRIGMVDYALE-------
-----------------SG--GASVIS--TRCSETYETKTALLSLFGIPLWYHSQSPRV-
ILQPDVHPGNCWAFQGPQGFAVVRLSARIRPTAVTLEHVPKA-LSPNSTISSAPKDFAIF
G-----------------F-----DEDLQ-QEGTLLGTFAYDQD-GEPIQ--TFYF--QT
SK--MAT------YQVVELR-------ILTNWGHPEYTCIYRF-RVHGEPAH--------
------------------------------------------

------------------------------------------------------------
---------------------------------------------------MSRRSQRLT
---RYS-QVDDDGGSSSSGGSSVAGSQSTLFKDSPLRTLK-RKSS--NMKHLSPVPQLGP
SSDPHTSYYSES--MVRESYIGSPQAVSL------ARSALLD-DRLHSEPYWS-------
---------------------------------------------------EDLHVRRRR
GT--GGTESSKANGLA-ES-KATEDFLGSSSGYSSEDDF---------------------
----AGYA-DIEQHSSGSR---LGSVVSRAG--SFVW-----------------------
------TVVTFPGRLFGLLYWWLGTSWYRLT-TAASLLDVFVLTRR--FS----SLKTF-
FWFLLLLLLLTGLTYGA--WYFYPFGLQTLHPAVVSWWAAKD----SRKQPEVWSSGDSA
LH---LQAEQRVLSQV--HILERRLEALATEFSSKWQRESIRLDR-LELQQGTAGQGG--
------GSGLSYED-----------TLALLEG--L--VSRR------E-AALKEDFRRDT
A---------------------A-----RIQEELAT---VRAEHHQDSEDLFKKIVQASQ
ESEAHIQQFKSEW----Q--RTMQEAIRENSA--QELGRLETQLAGLQQDLAALTLKQST
VEDEVGLLPQKIQAVRE-------EVESQFPAWVGHFL-LQ----G---GGTRAGL-LQR
EEVQA-----QLQELESKIL-AHVTKMQG-----RSAQEAAALLGQTLQKEGVVGVTEEQ
-----------------------VH----RIVKQALQ-RYSEDRIGMVDYALE-------
-----------------SG--GASVIS--TRCSETYETKTALLSLFGIPLWYHSQSPRV-
ILQPDVHPGNCWAFQGPQGFAVVRLSARIRPTAVTLEHVPKA-LSPNSTISSAPKDFSIF
G-----------------F-----DEDLQ-QEGSLLGTFTYDQD-GEPIQ--TFYF--QT
PK--MAT------YQVVELR-------ILTNWGHPEYTCIYRF-RVHGEPAPHP------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MP----------------
--------------R---------------------------SAR----------SPH--
-----GDPCALPDD-----------AAHNARQ--R----R-VIQRGRNTCRTAEDSLPNT
S-D-ALLFPV---------RLNT-PTLGLTQSVLGC--VSWFTC----------L-ACFL
RTQAQQV----------LFNTCRCKLIFQRLM--EKTGVLVLCAFG-----------FWM
FSMHLPSKMEVWQDDS---------INSPL----QSLR-MY----QEKVRHHTGEIQDLR
GSMN-------------QLL-ARLQEMEA--------------------------MSDEQ
K-----------------------------MTQKILK-MIQGDYIEKPDFALK-------
-----------------SI--GASIDF--EHTSATYNHDKARSYWNWIRLWNYAQPPDV-
ILEPNVTPGNCWAFVGDRGQVTIRLAQKVYLSNLTLQHIPKT-ISLSGSLDTAPKDFVIY
-----------------GM---E---S-SPREEVFLGAFQF-QP-ENTIQ--MFPL--QN
QP--PRA------FGSVKVK-------ISSNWGNPRFTCLYRV-RVHGSVTPPRTQPS--
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------MSERPRSRRKARYSVGSSE----EASS-SV---SMHGMLPEPR--
NSDSD-------------------------------------------------------
-----------------------------------RLTRSRKII----------ISVMF-
--------------------------------------TLTFLFVGL-------RNHRWP
RETEFLQKSRHICNLF-------AEYGSRLYSYQXXXX-XX----XXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXX--XXXXXX---------------XXXXX
---------------------XXXXXEMSNLVNYVLK-KFREDQVQMADYALK-------
-----------------SA--GASIIE--AETSESYKNDKAKLYWHGIGFLNYEMPPDI-
IPQPDVHPGKCWAFPGSQGHALIRLSRKIIPTAVTMDHISER-VSPSGNTYSAPKEFSIY
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------MRRSPRP--------------
------------GSAASSHNH---TPNFYSENSNSSHSATSGDSN--GR-RSAGPELGEP
EGR--RARGSSCGEPALSSGVPGGDTWAGSSRPKLAPRSHNGQ----TACGAAT-VRG-G
A-SEPSGSP--AVLEE---QLNLLPILDLRQEMPPP-PVSKSF-----------LSLFF-
----QVLSVFLSLVADGLVC--VYREICSIRFLFTAVSLLSIFLAA----------LWWG
LLYLIPPLENEPKE------------MLTLS--------QY----HHRVHSQGQQLQQLQ
AELSK-------------LH-KEVTSVRA--------------------------AHSE-
-----------------------------RVAKLVFQ-RLNEDFVRKPDYALS-------
-----------------SV--GASIDL--EKTSSDYEDRNTAYFWNRLSFWNYARPPSV-
ILEPDVFPGNCWAFEGEQGQVVIRLPGHVQLSDITLQHPPPT-VAHTGGASSAPRDFAVF
G-----------------L-----QADDD-ETEVFLGKFIF-EVQKSEIQ--TFHL--QN
DP--PSA------FPKVKIQ-------ILSNWGHPRFTCLYRV-RAHGVRISESAEDNAM
G--VTGG-----------------------PH----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----PAGSPV--APEE---QLDLLPTLELRQEMPTS-RVSKSI-----------LSHLF-
----QVPSVLLCLLGDVLVS--VYREVCSIRFLLTAVSLLSLFLAV----------LWWG
LLYLVLSLEHEPKE------------MLTMS--------EY----HERVCSQRQQLQQLQ
AELDK-------------LL-KEVASILF--------------------------TNSE-
-----------------------------TVAKIFIQ-RLNEDFVQNPDYPLI-------
-----------------SCXXXX--XX--XXXXXXXXXXXTAYFWNRFSFWNYARPPTV-
ILEPDVFPGNCWAFEGDQGQVVIRLPGRVQLSDITLQHPPPS-VAHTGGADSAPRDFEVY
G-----------------L-----QVDD--ETEVFLGKFTF-DVEKSEIQ--TFHL--QN
DP--PAA------FPKVKIQ-------ILSNWGHPRFTCLYRV-RAHGERTSEGSGENTQ
G--PH-------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------MSGKTKARRAAMFFRRCSE----DASGSAS----GNALLSED---
------------------------------------------------------------
E---------------------N-----PD---ANGVTRSWKII----------LSTML-
--------------------------------------TLTFLLVG-------LLNHQWL
KETDVPQKSRQLYAIVA-------EYGSRLYKYQARLR-MP----KEQLELLKKESQNLE
NNFRQILFLIKQIDVLKALL-RDMKDGMDNNH--NWNTHGDPV-----EDLDHTE-----
--------------------------EVSNLVNYVLK-KLREDQVKMADYALK-------
-----------------SA--GASIIE--AGTSESYKNNKAKLYWHGIGFLNHEMPPDI-
ILQPDVYPGKCWAFPGSQGHTLIKLATKIIPTAVTMEHISEK-VSPSGNISSAPKEFSVY
-----------------GI-----TKKCE-GEEIFLGQFIY-NKTGTTVQ--TFEL--QH
AV--SEY------LLCVKLN-------IFSNWGHPKYTCLYRF-RVHGTPGKHI------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------MQRRPRP--------------
------------GSAAFPHKH---TPNFYSDNSNSSMSITSGESC--GH-RSAGPEPGEP
EGR--RGRGSSCGEPAMSAGVPGRTTKAESSRLKPAPRSHSGP----TASGAAT-VRG-G
A-SEPAGSPG--VPEE---QLDL-STLDPRQEIPPP-RVSKSF-----------LSPLF-
----QVLSVLLSLVGGVLVS--VYREVCSVRFLLTAVSLLSLFLAA----------LWWG
LRYLAPPLENEPKE------------ILTLS--------EY----HERVRSQEQQLQQLR
AELVK-------------LH-KEVSSVRA--------------------------ANSE-
-----------------------------RVAKLVFQ-RLSEDFVRKPDYALS-------
-----------------SV--GASIDL--EKTSPDYEDANTAYFWNRFSFWNYARPPTV-
ILEPDVFPGNCWAFEGDQGQVVIQLPGRVQLSDITLQHPPPS-VAHTRGAKSAPRDFAVY
G-----------------L-----QVDD--ETEVFLGKFTF-DVEKSEIQ--TFHL--EN
DP--PAA------FPKVKIQ-------ILSNWGHPHFTCLYRV-RAHGIQTSEGAGDSAT
G--GAH------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------MLTLSWKII----------LCTVF-
--------------------------------------TSTFLLVG-------LQNHHWF
KETEFPQKPRQLYTVIA-------EYVSRLYNYQARLR-MP----KEQLELLKKESQTLE
NNFREILILIEQIDVLKALL-RDLKDGIHNH---SWSVPREAV-----QDKATTEVLDE-
--------------------------EMSNLVHYVLK-KFRGDQIQMADYALK-------
-----------------SA--GASVIE--AGTSESYKNNKAKLYWHGIGFLNYETPPDM-
ILQPDVHPGKCWAFPGSQGHILIKLARKIIPTAVTMEHISEK-VSPSGNTSSAPKEFSVY
-----------------GV-----LKKCE-GEEMLLGQFTY-NKTETTIQ--TFEL--QN
AA--SES------LLCVRLQ-------ILSNWGHPKYTCLYRF-RVHGIPSDHT------
------------------------------------------

------------------------------------------------------------
---------------------------------------------------MSRRSQRLT
---RYS-QGDDDGS-SSSGGSSVAGSQSTLFKDSPLRTLK-RKSS--NMKRLSPAPQLGP
SSDAHTSYYSES--LVHESW-------FP------PRSS-LE-E-LHGDANWG-------
---------------------------------------------------EDLRVRRRR
GT--GGSESSRASGLV-GR-KATEDFLGSSSGYSSEDDYVEDSEG----RGSKVTETEPV
SSFPAGYS-DVDQQSSSSR---LRSAVSRAG--SLLW-----------------------
------MVATSPGRLFRLLYWWAGTTWYRLT-TAASLLDVFVLTRR--FS----SLKTF-
LWFLLPLLLLTCLTYGA--WYFYPYGLQTFHPALVSWWAAKD----SRRPDEGWEARDSS
PH---FQAEQRVMSRV--HSLERRLEALAAEFSSNWQKEAMRLER-LELRQGAPGQGG--
------GGGLSHED-----------TLALLEG--L--VSRR------E-AALKEDFRRET
A---------------------A-----RIQEELSA---LRAEHQQDSEDLFKKIVRASQ
ESEARIQQLKSEW----Q--SMTQESFQESSV--KELRRLEDQLAGLQQELAALALKQSS
VAEEVGLLPQQIQAVRD-------DVESQFPAWISQFL-AR----G---GGGRVGL-LQR
EEMQA-----QLRELESKIL-THVAEMQG-----KSAREAAASLSLTLQKEGVIGVTEEQ
-----------------------VH----HIVKQALQ-RYSEDRIGLADYALE-------
-----------------SG--GASVIS--TRCSETYETKTALLSLFGIPLWYHSQSPRV-
ILQPDVHPGNCWAFQGPQGFAVVRLSARIRPTAVTLEHVPKA-LSPNSTISSAPKDFAIF
G-----------------F-----DEDLQ-QEGTLLGKFTYDQD-GEPIQ--TFHF--QA
PT--MAT------YQVVELR-------ILTNWGHPEYTCIYRF-R------VHGEPAH--
------------------------------------------

------------------------------------------------------------
---------------------------------------------------MSRRSQRLG
GTVRYYQSEDDG-NSSSSGGSSLLGGQQSLFKDISNSRSLRKKSG--SVKRPSPAPSLGT
SPATHTSFY-ES--VVTESYLNDGRGLSI------RGSTSL-DDPMDNSSYWS-------
---------------------------------------------------EDLSMRRRR
AGAGGIETSKKINGLSER---KIYDTYASSSGYSSEDDYAGYT-----------------
---------YSDQYTSGSG---FKKAVSKVG--AFLW-----------------------
------MVVTSPGRFFGLLYWWIGTTWYRLT-TAASLLDVFVLTRS--YP----ILKKL-
FLLLLLLLLLTAFGYGM--WYFYPFGLQSSV---FS-WGAMKFSSPVTKKEYEAGDSGV-
-I---PAAQQQVLSRL--QALERRFETLEAAAA-----------L-LELQKGK--SA---
-----EGSSLSHED-----------TLALLDG--L--VKRR------E-AAMREDFRTET
H---------------------L-----HLQSKLDA---FRSQMQQDFDHLQKKISQASE
ETEGRMLQMGSQW----Q--SSTQEGLMGSFR--KEMDRLEAQLSNLKKEFGNLASDQKV
LSKHVESLPRQIKEMRE-------DVEVQFPVWLSQFL-SQ----SRKE-GTGSLF-LQQ
DELQE-----HLLALEKKIL-ARISEDQE-----FSVQN----VRVALQREGVIGVTQED
-----------------------VH----RIVNQALN-RYSEDRIGMFDYALE-------
-----------------S--AGASVIS--TRCSETYETKTALLSLFGIPLWYHSQSPRV-
ILQPEVLPGNCWAFQGSQGFAVIRLSSNIYPTAVTLEHISRS-LSPKATIPSAPKDFAVY
G-----------------L-----EEEGL-QEGVLLGQFTYNQE-GDPIQ--TFHL--QD
ENRTSAA------FQLIELR-------VLSNWGHPEYTCIYRF-RVHGEPVS--------
------------------------------------------

------------------------------------------------------------
---------------------------------------------------MSRRSQRLT
---RYS-QGDD-DGSSSSGGSSVMGSQSTLFKDSPLRTLK-RKSS--SVKRLSPAPQLGP
SSDTHTSYYSES--LVRESYFL-------------ARSSILD-DQLHGDPYWS-------
---------------------------------------------------EDLRVRKRR
GT--GGTESSKINGLA-ET-KLSEDFLGSSSGYSSEDDYVEDNRR----GPFGVRQAELV
SSVPAGYS-ETGQWASGSR---LGSAVSQAG--SFFW-----------------------
------TLVTFPARLFGLLYWWVGTTWYRLT-TAASLLDVFVLT--RRFS----SLKAF-
LWFLLLLLLLTSLTYGA--WYFYPYGLQTFYPAVVSWWAAKG----SGRQHEAWESRDSS
PH---FQAEQRILSRV--HSLERRLEALAAEFSSNWQKEAMRLER-LELRQGTAGEG---
-----GGGGLSHED-----------TLALLEG--L--VSRR------E-AALKEDFRRDT
A---------------------T-----QIQEELVT---LRAEHQQDSEDLFKKIVQASQ
ESEAQLQHLKSEW----H--RMTQESFKESFM--KELGRLEGQLAGLRQELAALTLKQSS
VADQVGLLPQQLQAMRD-------DVESQFPAWVSQFL-LQ----G---GGSRTGL-LQR
EEMQA-----QLRELESKVL-AHVAEMQG-----KSAREAAAILGRTLQKEGVIGVTEEE
-----------------------VH----RIVNQALK-RYSEDRIGMVDYALE-------
-----------------SG--GASVIS--TRCSETYETKTALLSLFGIPLWYHSQSPRV-
ILQPDVHPGNCWAFQGPQGFAVVRLSALIRPTAVTLEHVPKS-LSPNSTISSAPKDFAVF
G-----------------L-----DEELQ-QEGMLLGQFTYDQD-GEPIQ--TFHF--QK
PT--VAT------YQVVELR-------ILTNWGHPEYTCVYRF-RVHGEPAH--------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------MSGKTKARRAAMFFRRCSE----DASGRAS----GNALLSED---
------------------------------------------------------------
E---------------------N-----PD---ANGVTRSWKII----------LSTML-
--------------------------------------TLTFLLVG-------LLNHQWL
KETDVPQKSRQLYSIIA-------EYGSRLYKYQARLR-MP----KEQLELLTKESQTLE
NNFRQILFLIEQIDVLKALL-RDMKDGMDNNH--NWNTHGDPV-----KDPDHTE-----
--------------------------EMSNLVNYVLK-KLREDQVQMADYALK-------
-----------------SA--GASIIE--AGTSESYKNNKAKLYWHGIGFLNHEMPPDI-
ILQPDVYPGKCWAFPGSQGHTLIKLATKIIPTAVTMEHISEK-VSPSGNISSAPKEFSVY
-----------------GI-----TKKCE-GEEIFLGQFIY-NKTGTTIQ--TFEL--QH
AV--SEY------LLCVKLN-------IFSNWGHPKYTCLYRF-RVHGTPGKYN------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------XX--XXX--------------
------------XXXXXXXXX---XXXXXXXXXXXXXXXXXXXXX--XX-XXXXXXXXXX
XXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----XXXXXXX-XXX-X
X-XXPAGPSV--VPEE---QQDLLPALDLRQERPPP-RVSKSF-----------LSLLF-
----QALSVLSAPIGDVLLT--VYREVCCIRFLLTAVSLLSLFLAA----------LWLG
ILYLVSPSEDEPTE------------MLTLS--------EY----RERVHAQGQQLQQLQ
AELSQ-------------LR-KEVCGVRT--------------------------ANSE-
-----------------------------RVAKLVFQ-RLNEDFVQKPDYALS-------
-----------------SV--GASIDL--EKTSHDYEDTNIAYFWNRFSFWNYARPPTV-
ILEPDVFPGNCWAFQGNQGQVVIRLPGRVQLSDITLQHPPPS-VAHSGGANSAPRDFSVF
G-----------------L-----QVDD--ETEVFLGRFAF-DLEKPEIQ--TFHL--QN
DP--PAA------FPKVKIK-------ILSNWGHPHFTCLYRV-RAHGVRTSEGAGDRAV
G--AARG-----------------------SH----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MP----------------
--------------R---------------------------SSR----------SPG--
-----DPGAP-LED-----------VAHNPRP--R----R-IAQRGRNTSRMVEDTSSNM
N-D-NFLLPV---------RINA-QALGLTQCMLGC--VSWFTC----------F-ACSL
RTQAQQV----------LFNTCRCKLLCQKLM--EKTGILLLCAFG-----------FWM
FSIHLPSKMKVWQDDS---------INGPL----QSL-RLY----QEKVRHHSGEIQDLR
GSMN-------------LLI-AKLQEMEA--------------------------MSDEQ
K-----------------------------VAQKIMK-MIHGDYIEKPDFALK-------
-----------------ST--GASIDF--EHTSATYNHEKAHSYWNWIQLWNYAQPPDV-
ILEPNVTPGNCWAFEGNRGQVTIQLAQKVYLSNLTLQHIPKT-ISPSGSLDTAPKDFVIY
-----------------GM---E---G-SPKEEVFLGAFQF-QP-ESIIQ--MFPL--QN
QP--ARA------FGAVKVK-------ISSNWGNPAFTCLYRV-RVHGSVAPPGEQPHQN
PYPERD------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------MP----KEQLELLKKESQTLE
NNFREILFLIEQMDMLKALL-RDMKDGTHSDS---GSGPRDVA-----RDQHSPEVPDE-
------------------------------------------------------------
----------------------ASIVE--SETSESYINNKTKLYWHGIGFLNHEMPPDI-
ILQPDVHPGKCWAFPGSQGHILIRLARKIIPMSVTMEHISEK-VSPSGNTSSAPKEFSVH
-----------------GL-----LKRCE-GEEIFLGRFIY-NKTEATVQ--TFDL--QR
EI--SES------LLCVRLK-------ILSNWGHPHYTCLYRF-RVHGIPSDHT------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MV----------LSTLW-
--------------------------------------ILTLLLVG-------LGNHRWL
KEAEFPQKSRHFYALVA-------EYGSRLYNYQARLR-MP----KEQLELLKKESQTLE
NNFREILFLIEQIDVLKALL-RDTQEDLHSY---SWNTDQDED-------QDPMEAT-E-
--------------------------EMSNLVNYVLK-KLREDQVQMADYALK-------
-----------------SA--GASIVE--AGTSESYKNNKAKLYWHGIGFLTYEMPPDI-
ILQPDVHPGKCWAFPGSQGHALIKLARKIVPTAVTMEHISEK-VSPSGNISSAPKEFSVY
-----------------GI-----SKQCE-GEEIFLGQFVY-NKTGSTVQ--TFEL--QH
DV--FES------LLCVKLK-------ILSNWGHPKYTCLYRF-RVHGTPGEY-------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------MRRSSRP--------------
------------GSASSPLKH---TPNFFSENSSMSVT--SEDSN--GR-GSAGPGPGEP
EGR--RAQGPSCGEPALGAGVPGGTTWAGSSREKPAPRSHNRE----TAG-GAA-TVR-G
GASEPTGSPV--VSEE---PLALLPTLDLRQEMPPP-RLSKSF-----------LSLLF-
----QVLRVSLSLAGDALVS--VYREVCSIRFLFTAVSLLSLFLAV----------IWLG
LLYLASPLENEPK------------EMLTLS--------EY----HERVRSQTQQLQQLQ
AELDK-------------LH-KEVSTVRA--------------------------ANSE-
-----------------------------RVAKLVFQ-RLSEDFVRKPDYALS-------
-----------------SV--GASIDL--EKTSHDYEDRNTAYFWNRFSFWNYARPPTV-
ILEPDVFPGNCWAFEGDQGHVVIRLPGRVQLSDITLQHPPPS-VAHTGGANSAPRDFAVF
G-----------------L-----QVDD--ETEVFLGKFIF-DVEKSEIQ--TFHL--QN
DP--PAA------FPKVKIQ-------ILSNWGHPRFTCLYRV-RAHGVRTSEGDEGSAT
G--GPH------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MP----------------
--------------R---------------------------SSR----------SPG--
-----DPGAL-LED-----------VAHNPRP--R----R-IAQRGRNTSRMAEDTSPNM
N-D-NFLLPV---------RINA-QALGLTQCMLGC--VSWFTC----------F-ACSL
RTQAQQV----------LFNTCRCKLLCQKLV--EKTGILLLCAFG-----------FWM
FSIHLPSKMKVWQDDS---------INGPL----QSL-RLY----QEQVRHHSGEIQDLR
GSMN-------------LLI-AKLQEMEA--------------------------MSDEQ
K-----------------------------MAQKIMK-MIHGDYIEKPDFALK-------
-----------------ST--GASIDF--EHTSATYNHEKAHSYWNWIQLWNYAQPPDV-
ILEPNVTPGNCWAFEGDRGQVTIQLAQKVYLSNLTLQHIPKT-ISLSGSLDTAPKDFVIY
-----------------GM---E---G-SPKEEVFLGAFQF-QP-ENVIQ--MFPL--QN
QP--ARA------FSAVKVK-------ISSNWGNPGFTCLYRV-RVHGSVAPPREQPHQN
PYPERD------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------MRRSSRP--------------
------------GSASSSRKH---TPNFFSENSSMSIT--SEDSK--GL-RSAEPGPGEP
EGR--RARGPSCGEPALSAGVPGGTTWAGSSQQKPAPRSHNWQ----TAC-A-A-TVR-G
GASEPTGSPV--VSEE---PLDLLPTLDLRQEMPPP-RVFKSF-----------LSLLF-
----QGLSVLLSLAGDVLVS--MYREVCSIRFLFTAVSLLSLFLSA----------FWLG
LLYLVSPLENEPK------------EMLTLS--------EY----HERVRSQGQQLQQLQ
AELDK-------------LH-KEVSTVRA--------------------------ANSE-
-----------------------------RVAKLVFQ-RLNEDFVRKPDYALS-------
-----------------SV--GASIDL--QKTSHDYADRNTAYFWNRFSFWNYARPPTV-
ILEPHVFPGNCWAFEGDQGQVVIQLPGRVQLSDITLQHPPPS-VEHTGGANSAPRDFAVF
G-----------------L-----QVYD--ETEVSLGKFTF-DVEKSEIQ--TFHL--QN
DP--PAA------FPKVKIQ-------ILSNWGHPRFTCLYRV-RAHGVRTSEGAEGSAQ
G--PH-------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MP----------------
--------------R---------------------------SSR----------SPG--
-----DPGAL-LED-----------VAHNPRP--R----R-IAQRGRNTSRMAEDTSPNM
N-D-NILLPV---------RNND-QALGLTQCVLGC--VSWFTC----------F-ACSL
RTQAQQV----------LFNTCRCKLLCQKLM--EKTGILLLCAFG-----------FWM
FSIHLPSKMKVWQVSA---------PRLTD----LTLTSQYHLHSSIHSHQIGGEIQDLR
GSMN-------------QLI-AKLQEMEA--------------------------MSDEQ
K-----------------------------MAQKIMK-MIHGDYIEKPDFALK-------
-----------------SI--GASIDF--EHTSATYNHEKAHSYWNWIQLWNYAQPPDV-
ILEPNVTPGNCWAFEGDRGQVTIQLAQKVYLSNLTLQHIPKT-ISLSGSLDTAPKDFVIY
-----------------GM---E---G-SPKEEVFLGAFQF-QP-ENIIQ--MFPL--QN
QP--ARA------FGAVKVK-------ISSNWGNPGFTCLYRV-RVHGSVAPPREQPHQN
PYPERD------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------MVIGELWRFPGNSSVPYIQVEQPSLLWLALQG-S--------------------
-----------------------------------WE--ATLCPVLFLLTSTLLCLSSQA
-----------------------VQ----KIIHQVLE-KLEESPFQMTNYASK-------
-----------------TS--GAAIVR--SKTSPSWIG-SGRVFWQSLPLVAYMRPPEV-
ILEPDNHPGNCWPFPGSQGHVFIKLPVAVFPTAVTINHGVPAAAYHADSISSAPKDFAVY
G-----------------L-----QEEDD-EKGTLLGEFIF-MPGQAPGQ--TFQL--KN
EH--SAF------IKYVRLQ-------VLSNWAIRSTPACINSGSTAIQPLMVTRG---E
SYLPR-----------------GM-LAGLLL---NKLL----

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------MLTRSWKII----------LSTVF-
--------------------------------------ISTFLLVG-------LLNHQWL
KETEFSQKPRQLYTVIA-------EYGSRLYNYQARLR-MP----KEQQELLKKESQTLE
NNFREILFLIEQIDVLKALL-KDMKDGVHNH---SFPVHRDAV-----QDQATTDVLDE-
--------------------------EISNLVHYVLK-KFRGDQIQLADYALK-------
-----------------SA--GASVIE--AGTSESYKNNKAKLYWHGIGFLNYEMPPDM-
ILQPDVHPGKCWAFPGSQGHILIKLARKIIPTAVTMEHISEK-VSPSGNISSAPKEFSVY
-----------------GV-----MKKCE-GEEIYLGQFIY-NKMEATIQ--TFEL--QN
EA--SES------LLCVKLQ-------ILSNWGHPKYTCLYRF-RVHGIPSDYT------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------MSGRPKLRRSARFFRGHSE----EASSSAS----LSTLLSEPE--
L-----------------------------------------------------------
G---------------------N-----AD---ANGLTQSWKIV----------ISTAS-
--------------------------------------ILTLLLIG-------LGNHMWL
KETEFPQRSRQFYALIA-------EYGSRLYNYQARLR-MP----KEQLELLKKESQTLE
NNFREILFLIEQIDVLKALL-RDTRDGLH-Y---SWNADGGKD-------PEPLEATEE-
--------------------------EMSNLVNYVLK-KLREDQVQMADYALK-------
-----------------SA--GASVIE--AGTSESYKNNKAKLYWHGIGFLTYEMPPDI-
ILQPDVHPGKCWAFPGSQGHALIKLARKIKPTAITMEHISEK-VSPSGNISSAPKEFSVY
-----------------GI-----SKQCE-GEEIFLGQFVY-NKTGSTVQ--TFKL--QH
DV--SES------LLCVKLK-------ILSNWGHPKYTCLYRF-RVHGTPGENP------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-------------------------------------TLK-KKSG--NMKRLSPAPQLGP
SSDRHTSYYSES--VVRESYFGSP-----------PRNSILD-DQLRGDPFWS-------
---------------------------------------------------EDLRVRR-R
DT--GGTESSKVNGLP-EN-KLSEDFLGSSSGYSSEDDYVEDSGG----GGTRVRTTG-V
SSSSAGYS-ETDQQGSGSR---LRNAVSRAG--SLFW-----------------------
------MVFTSPGRLFGLLYWWIGTTWYRLT-TAASLLDVFVLT--RRFS----SLKTF-
LWFLLLLLLLTGLTYGA--WYCYPFGLQTFHPAVASWWASKG----SSGQRAVWGSRDSS
PH---FQAEQRILSRV--HSLERRLEALAAEFSSSWQKEAMRLER-LELRQGAGGQG---
-----GSGSLSHED-----------TLALLEG--L--VSRR------E-AALKEDFRRDT
A---------------------A-----QIQEELVT---LRAEHQQDSEDLFKKIVQASQ
ESEARLQELKSEW----Q--RMTQESFRESSM--KELGRLGVQLEGLRQELAALTLKQSS
VEDQVGLLPQQLQAVRD-------DVESQFPAWVSQFL-LR----G---GGSRTGL-LQR
EEVQA-----QLQELESKIL-ARVAEMQG-----KSAREAVASLGLTLQKEGVIGVTEEQ
-----------------------VH----RIVNQALK-RYSEDRIGMVDYALE-------
-----------------SG--GASVIS--TRCSETYETKTALLSLFGIPLWYQSQSPRV-
ILQPDVHPGNCWAFQGPQGFAVVRLSARIRPTAVTLEHVPKS-LSPNSTISSAPKDFAVF
G-----------------F-----DEDLQ-QEGMLLGQFTYDQD-GEPIQ--TFYF--QG
PK--MAA------YQVVELR-------ILTNWGHPEYTCIYRF-RVHGEPTH--------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------CTPNPPDT-
ILQPDVSLGNCWAFQGSRGQVVIRLPAKIQATMVTVHHTSDM-DSALGKFSSAPRDFTV-
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----PAGSPV--VSEEQQQQLDLLSALDLRREMPPP-RAPKNF-----------LSLLF-
----QVLSPLMSLVGAVLGS--VYREVCSIRFLFTAVSLLSVFAAA----------LWWG
LLYLAPPLENEPRE------------MLTIS--------EY----HQRVNSQGQQLQQLQ
AELVK-------------LH-KEVSSVRA--------------------------AHSE-
-----------------------------RVAKLVFQ-RLNEDFVRKPDYALS-------
-----------------SV--GASIDL--EKTSLDYEDTNTVYFWNRLSFWNYARPPSV-
ILEPDVFPGNCWAFEGDQGQVVIRLPGRVQLSDITLQHPPPS-VAHTGGASSAPRDFAVF
G-----------------L-----LVDD--ETEVFLGKFTF-DVHKSEIQ--TFQL--QN
DP--PSA------FPKMKIQ-------ILSNWGHPRFTCLYRV-RAHGVRTSEWAGDGAT
G--ATGS-----------------------H-----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------MSGKAKARRAAMFFRGCSE----DASSSTS----GNTLLSED---
------------------------------------------------------------
E---------------------N-----PD---ANGVTRSWKII----------LSTMF-
--------------------------------------TLIFLLVG-------LLSHQWL
KETEVPQKSRQLYAIIA-------EYGSRLYKYQARLR-MP----KEQLEFLKKESQTLE
NNFRKILLLIEQIDVLKALL-RDMKDGTDNNH--SWNTHGDPV-----EDPDHTE-----
--------------------------EMSNLVNYVLK-KLREDQVQMADYALK-------
-----------------SA--GASIIE--AGTSESYKNNKAKLYWHGISFLNHEMPPDI-
ILQPDVYPGKCWAFPGSQGHTLIKLATKIIPTAVTMEHISEK-VSPSGNISSAPREFSVY
-----------------GV-----TKKCE-GEEIFLGQFIY-NKTGTTVQ--TFEL--QH
AV--SEY------LLCVKLN-------IFSNWGHPKYTCLYRF-RVHGTPGKHI------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------MDVSF-
SLLPDISPGSCWAFQGSQGHVVIRLPEKIQPRAFTIWHISRA-VSPCGEVSSAPEEFAVS
V-----------------S-----LCL-----------LL--LLEGPRAR--GRAL--PE
MS-----------FWW--------------------------------------------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------MRRSPRP--------------
------------GSAAPPHKH---NPDFYSDRSNSSVSATSRDSL--RGERKGAPPRGLK
GGGRGGRRAPPCSESIPRAEAAGGPRWAGSCLPSRAIRRRAEP----TVCGWAP-VRR-G
A-----------------------------------------------------------
-----------------------LSEVRSLRFLLAALLFFSVFTA---------------
-------------ETK---------EFLTLS--------EY----HEKVHSQGLELQQLQ
TELTK-------------LH-TDVSGIRA--------------------------ANSE-
-----------------------------XXXXXXXX-XXXXXXXXXXXXXXX-------
-----------------XX--XXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-
XXXPDVFPGNCWAFQGSKGQVVIRLPGQVQLSDITLQHPPRS-VAHTGGANSAPKDFAVF
G-----------------L-----QGDD--KTEILLGKFTF-EVEKSEIQ--TFHL--KN
EP--PMA------FPKVKIQ-------ILSNWGHPRFTCLYRV-RAH-------------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MP----------------
--------------R---------------------------SPR----------SPG--
-----D-SCDPPRD-----------VAHVPRE--IRPR--RIIQRGRNICRMAEEPLSNT
--SDAVLLPI---------RISV-PAPGLTQCMLGC--MSWIAC----------L-VCFL
RTQAHQV----------LFNNCRCRLLFHKLM--EKTGVLVLCAFG-----------FWV
FSMHLPSKLEVWQDDS---------IHSPL----QSLR-MY----QEKVRHHTG-IQDLR
GNIN-------------QLI-AKLQEMEA--------------------------MSDEQ
K-----------------------------MAQKIMK-MIQGDYIEKPDFALK-------
-----------------SI--GATIDF--EQTSATYNHDKARSYWNWIRLWNYAQPPDV-
ILEPNVTPGNCWAFAGDRGQVTIRLAQKVYLSNLTLQHIPKT-ISLSGSLDTAPKDFVIY
-----------------GM---E---G-SPREEVFLGAFQF-QP-ENIIQ--MFQL--QN
QP--PRT------FGAVKVK-------ISSNWGNPRFTCLYRV-RVHGSVTPPREQPHQT
PAHPKRD-----------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MP----------------
--------------R---------------------------SSR----------SPG--
-----DPGAP-LED-----------VAHNPRP--R----R-IAQRGRNTSRMVEDTSSNM
N-D-NFLLPV---------RINA-QALGLTQCMLGC--VSWFTC----------F-ACSL
RTQAQQV----------LFNTCRCKLLCQKLM--EKTGILLLCAFG-----------FWM
FSIHLPSKMKVWQDDS---------INGPL----QSL-RLY----QEKVRHHSGEIQDLR
GSMN-------------LLI-AKLQEMEA--------------------------MSDEQ
K-----------------------------VAQKIMK-MIHGDYIEKPDFALK-------
-----------------ST--GASIDF--EHTSATYNHEKAHSYWNWIQLWNYAQPPDV-
ILEPNVTPGNCWAFEGNRGQVTIQLAQKVYLSNLTLQHIPKT-ISPSGSLDTAPKDFVIY
-----------------GM---E---G-SPKEEVFLGAFQF-QP-ESIIQ--MFPL--QN
QP--ARA------FGAVKVK-------ISSNWGNPAFTCLYRV-RVHGSVAPPGEQPHQN
PYPERD------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------MKSIQKGIP-NSIKQILK--------------------ENDIPGENKDQ
-----------------------VL----EMINQAFR-KTYEDHVQMPDWAQK-------
-----------------TI--GATIDH--SRTSKSYEPENAKSCWYKYFFISTAKPPET-
ILQPDVYPGNCWAFHGSEGQVVIKLPERIFPTAVTVQHIPRA-VSPVKGVTSALKDFSVY
G-----------------I-----DDEIN-EET-LLGTFMY-DIEKETIQ--TFQL--QK
EA--AKQ------FLCMKFK-------VQSNWGNAEFTCIYRV-RVHGNMSGNSVP---S
EKGQK-------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------MLTLSWKII----------LSTMF-
--------------------------------------TSTFLLFG-------LQNHPRF
KEKKVSQKPRQISSIIE-------EYGTRIYNYQARLR-LP----KEQLELLKKESQTLE
NNFREILLLTEQIDVLKALL-RDMKDGIHNH---SWPAHQEAV-----QNQGTTEVLDD-
--------------------------EVSDLVHYVLK-KFRGDQIQMADYALK-------
-----------------SA--GASVIE--SGTSESYKNNKAKLYWHGIGFLNYEMPPDM-
ILQPDVHPGKCWAFPGSQGHILIKLARKIIPTAVTMEHISEK-VSPSGNTSSAPKEFSVY
-----------------GM-----MKRCE-GEEMLLGQFMY-NKAETTVQ--TFEL--QN
KA--PES------LLCVKLQ-------ILSNWGHPKYTCLYRF-RVHGIPSDHT------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------MDVSF-
SLLPDISPGSCWAFQGSQGHVVIRLPEKIQPRAFTIWHISRA-VSPCGEVSSAPEEFAVS
V-----------------S-----LCL-----------LL--LLEGPRAR--GRAL--PE
MS-----------FWW--------------------------------------------
------------------------------------------

MGCGLSALTDRRTHTHSATRAPSGPTRAAQFSAGRIVR----LPARLPPLPAHPGS----
------------------------PRRPPL---PGFRRDSLQGKSPPAHLIMSRRSQRLT
---RYSSQGDDDGGSSSSGGSSVMGSQSTLFKDSPLRTLK-KKSN--NSKRLSPAPQLGP
SSDAHTSYYSES--VVRESYIGSPRAASIAA--SLTRNSLLD------DPYWS-------
---------------------------------------------------EDLRVRRRR
GT--GGTDSSKVNGLP-EN-KLSEDFLGSSSGYSSEDDYV--------------------
-----GYS-ETDHRDSGSR---LRNAVSRAG--CLLW-----------------------
------MVVTSPGRLFGLLYWWIGTTWYRLT-TAASLLDVFVLT--RRFS----SLKTF-
LWFLLLLLLLTGLTYGA--WYFYPFGLQTLHPAVVSWWASKG----SIGQREVWESRDSS
PH---FQAEQRILSRV--HSLERRLDALAAEFSSSWQKEAMRLER-LELQQGAGRQG---
----GGGGGLSHED-----------TLALLEG--L--VSRH------E-AALKEDLRRDT
A---------------------A-----RIQEELVT---LRSEHQQDSEDLFKKIVQASQ
EYEARLQQLKSEW----Q--RMTQESFQENAM--KELGRLEGQLAGLRQELAALTLKQSS
VEDQVGLLPQKLQAVRD-------DVESQFPAWVSQFL-LR----G---GGTRTGL-LQR
EEMEA-----QLRDLESKIL-THVAEMQG-----KSAREAVASLGLTLQREGVIGVTEEQ
-----------------------VH----RIVSQALK-RYSEDRIGMVDYALE-------
-----------------SG--GASVIS--TRCSETYETKTALLSLFGIPLWYHSQSPRV-
ILQPDVHPGNCWAFQGPQGFAVVRLSARIRPTAVTLEHVPKS-LSPNSTISSAPKDFAIF
G-----------------F-----DEDLQ-QEGTLLGQFTYDQD-GEPIQ--TFYF--QD
PK--MAT------YQVVELR-------ILTNWGHPEYTCIYRF-RVHGEPAH--------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------MSGKTKARRAAMFFRRCSE----DASGSAS----GNALLSED---
------------------------------------------------------------
E---------------------N-----PD---ANGVTRSWKII----------LSTML-
--------------------------------------TLTFLLVG-------LLNHQWL
KETDVPQKSRQLYAIVA-------EYGSRLYKYQARLR-MP----KEQLELLKKESQNLE
NNFRQILFLIEQIDVLKALL-RDMKDGMDNNH--NWNTHGDPV-----EDPDHTE-----
--------------------------EVSNLVNYVLK-KLREDQVEMADYALK-------
-----------------SA--GASIIE--AGTSESYKNNKAKLYWHGIGFLNHEMPPDI-
ILQPDVYPGKCWAFPGSQGHTLIKLATKIIPTAVTMEHISEK-VSPSGNISSAPKEFSVY
-----------------GI-----TKKCE-GEEIFLGQFIY-NKTGTTVQ--TFEL--QH
AV--SEY------LLCVKLN-------IFSNWGHPKYTCLYRF-RVHGTPGKHI------
------------------------------------------

------------------------------------------------------------
---------------------------------------------------MSRRSQRLT
---RYS-QVDDDGGSSSSGGSSVAGSQNTLFKDSPLRTLK-RKSS--NMKRMSPAPQLGP
SSDSHTSYYSES--MVRESYIGSPQAVSL------ARSALLD-DHLHSEPYWG-------
---------------------------------------------------EDLRVRRRR
GT--GGTESSKANGLA-ES-KATEDFLGSSSGYSSEDDFT--------------------
----TGYA-DMDQHSSGSK---LGSVVSRAG--SFVW-----------------------
------TVITFPGRLFGLLYWWLGTTWYRLT-TAASLLDVFVLTRR--FS----SLKTF-
LWFLLLLLLLTGLTYGA--WYFYPFGLQTLHPAVVSWWTARD----SRKQPELWDSRDSA
PH---FQAEQRILSKV--NSLERRLEALAAEFSSNWQRESIRLER-LELRQGAPGQGG--
------GSGLSQED-----------TLALLEG--L--VSRR------E-AALKEDFRRDT
A---------------------T-----RIQEELAA---VRAEHHQDSEDLFKKIVQASQ
ESEARIQHLKSEW----Q--SMTQEAIQENSV--QELGRLEAQLAGLRQELAALTLKQSS
VEDEVGLLPQKIQAVRQ-------EVESQFPAWVSHFL-LQ----G---GGARSGL-LQR
EEVQA-----QLQELESKIL-AHVTEMQG-----KSAREAAALLGRTLQNEGVVGVTEEQ
-----------------------VH----QIVKQALQ-RYSEDRIGMVDYALE-------
-----------------SG--GASVIS--TRCSETYETKTALLSLFGIPLWYHSQSPRV-
ILQPDVHPGNCWAFQGPQGFAVVRLSARIRPTAVTLEHVPKA-LSPNSTISSAPKDFAIF
G-----------------L-----DEDLQ-QEGVLLGTFTYDQD-GEPIQ--TFYF--QT
PK--MAA------YQVVELR-------ILTNWGHPEYTCIYRF-RVHGEPTH--------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------MSGKTKARRAAVFFRRCSE----DASGSAS----GNALLSED---
------------------------------------------------------------
E---------------------N-----PD---ANGVTRSWKII----------LSTML-
--------------------------------------TLTFLLVG-------LLNHQWL
KETDVPQKSRQLYAIVA-------EYGSRLYKYQARLR-MP----KEQLELLKKESQTLE
NNFRQILFLIEQIDVLKALL-RDMKDGMDNNH--NWNTHGDPV-----EDPDHTEVLDEQ
S-------DMDHLPPSRPHFILVTVKEMSNLVNYILK-KLREDQVEMADYALK-------
-----------------SA--GASIIE--AGTSESYKNNKAKLYWHGIGFLNHEMPPDI-
ILQPDVYPGKCWAFPGSQGHTLIKLATKIIPTAVTMEHISEK-VSPSGNISSAPKEFSVY
-----------------GI-----TKKCE-GEEIFLGQFIY-NKTGTTVQ--TFEL--QH
TV--SEY------LLCVKLN-------IFSNWGHPKYTCLYRF-RVHGTPGKHI------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------MLIAAFVFG-----CTGSSVGLMTPLLPAL-
CFQLDMSPGYCWRLKASQSQVVFNLPTKVQPTAVTVQHSVETN---LWHVSSAPRDFAVF
G-----------------L-----DEEGE--KEALLGKFTY-DVRKEVTQ--TFQL--QV
QS--LRM------GRR-----------------PFQKHCFGSK-SVAGGVLGSPCQGRGP
ARAQRNT-------LRFRGPRARD-MAG--------------

------------------------------------------------------------
---------------------------------------------------MSRRSQRLT
---RYS-QGDDDGGSSSSGGSSVAGSQSTLFKDSPLRTLK-RKSS--NMKRLSPAPQLGP
SSDAHTSYYSES--LVRESYIGT---AFP------PRSA-LE-E-LHGDADWG-------
---------------------------------------------------EDLRVRRRR
GT--GGSESSRASGLV-GR-KATEDFLGSSSGYSSEDDYM--------------------
-----GYS-DADQQSSGSR---LRNAVSRAG--SLLW-----------------------
------MVVTSPGRLFRLLYWWAGTTWYRLT-TAASLLDVFVLTRR--FS----SLKTF-
LWFLLPLLLLTCLTYGA--WYFYPYGLQTFHPALVSWWAAKD----SRRQDEGWESRDS-
SH---FQAEQRVMSRV--HSLERRLEALAAEFSSNWQKEAMRLER-LELRQGAPGQGG--
------GGGLSHED-----------TLALLEG--L--VSRR------E-AALKEDFRREA
A---------------------A-----HIQEELSA---LRAEHQQDSEDLFKKIVRASQ
ESEARIQQLKSEW----Q--SMTQESFRESSV--KELRRLEDQLAGLQQELAALALKQSL
VADEVGLLPQQIQAVRD-------DVESQFPAWISQFL-AR----G---GGGRMGL-LQR
EEMQA-----QLRELESKIL-THVAEMQG-----KSAREAAASLGVTLQKEGVIGVTEEQ
-----------------------VH----RIVKQALQ-RYSEDRIGLADYALE-------
-----------------SG--GASVIS--TRCSETYETKTALLSLFGIPLWYHSQSPRV-
ILQPDVHPGNCWAFQGPQGFAVVRLSARIRPTAVTLEHVPKA-LSPNSTISSAPKDFAIF
G-----------------F-----DEDLQ-QEGTLLGKFTYDQD-GEPIQ--TFHL--QA
PS--MAT------YQVVELR-------ILTNWGHPEYTCIYRF-R------VHGEPAH--
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------MRRSPRS--------------
------------GSAASSHNH---TPNFYSENSNSSHSATSGDSN--GR-RSAGPELGEP
EGR--RARGSSCGEPALSPGMPGGDTWAGSSRPKLAPRSHNGQ----TACGAAT-VRG-G
A-SEPSGSS--VVLEE---QLNLLPILDLRQEMPTP-RVSKSF-----------LSLLF-
----QVLSMVLSLAVDGLVC--VCREICSIRFLFTAVSLLSIFLAA----------LWWG
LLYLIPPLENEPTE------------MLTLS--------QY----HHRVHSQGQQLQQLQ
AELNK-------------LH-KEVSSVRA--------------------------AHSE-
-----------------------------RVAKLVFQ-RLNEDFVRKPDYALS-------
-----------------SV--GASIDL--EKTSSDYEDQNTAYFWNRLSFWNYARPPSV-
ILEPDVFPGNCWAFEGDKGQVVIRLPGHVQLSDITLQHPPPT-VAHTGGASSAPRDFAVY
G-----------------L-----QAD-D-ETEVFLGKFIF-DVQKSEIQ--TFHL--QN
DP--PSA------FPKVKIQ-------ILSNWGHPRFTCLYRV-RAHGVRTSEWADDNAT
G--VTGG-----------------------PH----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------MEGIL-HSVQEILE--------------------ESDIPGENRDQ
-----------------------VL----EMINVAFK-KVYEDRVQMPDWAQK-------
-----------------SI--GATIDT--DRTSKSYELGKTEGCCFSSWFFSSANPPDI-
ILQPDVHPGNCWAFQGSQGQVVIRLPEKIYPTAVTIQHISKA-ISPSGDVTSAPKDFAVC
G-----------------L-----NEETG-KET-LLGTFIY-DSGKESIQ--TFQL--EG
EL--SKS------FVYIKFN-------VLSNWGNAEYTCVYRV-RVHGKRTNSS------
------------------------------------------

------------------------------------------------------------
---------------------------------------------------MSRRSQRLT
---RYS-QVDDDGGSSSSGGSSVAGSQSTLFKDSPLRTLK-RKSS--NMKRLSPVPQLGP
SSDPHTSYYSES--MA----------VSL------ARSALLD-DP-------G-------
---------------------------------------------------EDLHVRRRR
GT--GGTESSKANGLA-ES-KATEDFLGSSSGYSSEDDF---------------------
----AGYA-DMEQHSSGSR---LGSVVSRAG--SFVW-----------------------
------TVVTFPGRLFGLLYWWLGTSWYRLT-TAASLLDVFVLTRR--FS----SLKTF-
FWFLLLLLLLTGLTYGA--WYFYPFGLQTLHPAVVSWWAAKD----SRKQPEVWSSGDSA
LH---LQAEQRVLSQV--HILERRLEALATEFSSKWQRESIRLDR-LELQQGTAGQGG--
------GSGLSYED-----------TLALLEG--L--VSRR------E-AALKEDFRRDT
A---------------------A-----RIQEELAT---VRAEHHQDSEDLFKKIVQASQ
ESEAHIQQFKSEW----Q--RTMQEAIRENSA--QELGRLETQLAGLQQDLAALTLKQST
VEDEVGLLPQKIQAVRE-------EVESQFPAWVGHFL-LQ----G---GGTRAGL-LQR
EEVQA-----QLQELESKIL-AHVTKMQG-----RSAQEAAALLGQTLQKEGVVGVTEEQ
-----------------------VH----RIVKQALQ-RYSEDRIGMVDYALE-------
-----------------SG--GASVIS--TRCSETYETKTALLSLFGIPLWYHSQSPRV-
ILQPDVHPGNCWAFQGPQGFAVVRLSARIRPTAVTLEHVPKA-LSPNSTISSAPKDFSIF
G-----------------F-----DEDLQ-QEGSLLGTFTYDQD-GEPIQ--TFYF--QT
PK--MAT------YQVVELR-------ILTNWGHPEYTCIYRF-RVHGEPAPHP------
------------------------------------------

MGCGLSALTDRRTHTQSATRAPPGPTRAARASTGRIVRPPAS--YRVAALRVPARPGPGR
RFALRGAPPAGSPRGKGARPGGGRASNAPGRVRSRRGSRFSSGEESTSHLIMSRRSQRLT
---RYS-QGDDDGS-SSSGGSSVAGSQSTLFKDSPLRTLK-RKSS--NMKRLSPAPQLGP
SSDAHTSYYSES--LVRESYIGT---AFP------PRSA-LE-E-LHGDADWG-------
---------------------------------------------------EDLRVRRRR
GT--GGSESSRASGLV-GR-KAAEDFLGSSSGYSSEDDYM--------------------
-----GYS-DADQQSSGLR---LRNAVSRAG--SLLW-----------------------
------MVATSPGRLFRLLYWWAGTTWYRLT-TAASLLDVFVLTRR--FS----SLKTF-
LWFLLPLLLLTCLTYGA--WYFYPYGLQTFHPALVSWWAAKD----SRRQDEGWESRDS-
SH---FQAEQRVMSRV--HSLERRLEALAAEFSSNWQKEAMRLER-LELRQGAPGQGG--
------GGGLSHED-----------TLALLEG--L--VSRR------E-AALKEDFRREA
A---------------------A-----RIQEELSA---LRAEHQQDSEDLFKKIVRASQ
ESEARIQQLKSEW----Q--SMTQESFRESSV--KELRRLEDQLAGLQQELAALALKQSL
VADEVGLLPQQIQAVRD-------DVESQFPAWISQFL-AR----G---GGGRVGL-LQR
EEMQA-----QLRELESKIL-THVAEMQG-----KSAREAAASLGVTLQKEGVIGVTEEQ
-----------------------VH----RIVKQALQ-RYSEDRIGLADYALE-------
-----------------SG--GASVIS--TRCSETYETKTALLSLFGIPLWYHSQSPRV-
ILQPDVHPGNCWAFQGPQGFAVVRLSARIRPTAVTLEHVPKA-LSPNSTISSAPKDFAIF
G-----------------F-----DEDLQ-QEGTLLGKFTYDQD-GEPIQ--TFHF--QA
PS--MAT------YQVVELR-------ILTNWGHPEYTCIYRF-R------VHGEPAH--
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------MMSGRPQLRRGVGLFRGSPE----GACCSAS----FQGLLSEP---
------------------------------------------------------------
E---------------------N-----PE---AHGIPRSWKIT----------LGITF-
--------------------------------------TLIFLLIG-------LRNQQWL
QEAEFSQTSRQLYAAVA-------EFGSRLYNYQARLR-MP----KEHLELLKKESQTLE
NNFREILFLIEQINALKVLL-RELQEGAHNR---SWRAAQ---------DQDGAADPDE-
--------------------------EMSHLVNYVLKKKLREDQVQMADYALK-------
-----------------SAVVGASIIE--SGTSESYKNDKAKLYWHGIGFLNYEMPPDV-
ILQPDVHPGKCWAFPGSQGHALIKLARKIVPSAVTLEHISEK-VSPSGNISSAPKEFSVY
-----------------GV-----MKKCE-GEGIFLGQFIY-NKTETTVQ--TFEL--QH
EV--PES------ISCVKLK-------VLSNWGHPQYTCLYRF-RVHGTPSDHT------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------V--ERTSKSYGGNRWL----SP-FFSSAKPPET-
ILQPDISAGNCWAFQGSRGHVVIRLPEKIWPTAFTIWHISKA-VSPSGEVSTAPREFVVS
G-----------------V-----DED-E-GEA-LLGSFIY-DVDGEIAQ--TFQV--QE
EP--RKA------FRQIKLE-------VRSNWGNKEYTCLYRA-DVHGNPEKA-------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------LTQSLWKIT----------LSIIF-
--------------------------------------LSTFLLIG-------HRNHQWL
KETAMPQKYEQLYAIFA-------EYGTRLYHYQARFR-KP----REQLELLKKESQTLE
NNFREILVLTEQIATLKALL-RDMQDGTPRDS---G--LKDVT-----RDQDNAEVPDE-
--------------------------EMFQLVHYVLK-RLREDQVQMADYALK-------
-----------------SA--GASIVE--SETSESYINNKTKLYWHGIGFLNHEMPPDI-
ILQPDVHPGKCWAFPGSQGHILIRLARKIIPMSVTMEHISEK-VSPSGNISSAPKEFSVH
-----------------GL-----MKRCE-GEEVFLGRFIY-NKTEATVQ--TFDL--QH
EI--SES------LLCVRLK-------ILSNWGHPQYTCLYRF-RVHGIPSDHT------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------LTQSLWKIT----------LSIIF-
--------------------------------------LSTFLLIG-------HRNHQWL
KETAMPQKYEQLYAMFA-------EYGTRLYHYQARFR-KP----REQLELLKKESQTLE
NNFREILVLTEQIATLKALL-RDMQDGTPRDS---G--LRDVT-----RDQDNAEVPDE-
--------------------------EMFQLVHYVLK-RLREDQVQMADYALK-------
-----------------SA--GASIVE--SETSESYINNKTKLYWHGIGFLNHEMPPDI-
ILQPDVHPGKCWAFPGSQGHILIRLARKIIPMSVTMEHISEK-VSPSGNISSAPKEFSVH
-----------------GL-----MKRCE-GEEVFLGRFIY-NKTEATVQ--TFDL--QH
EI--SES------LLCVRLK-------ILSNWGHPQYTCLYRF-RVHGIPSDHT------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------MRRSPRP--------------
------------GSAASQHKH---TPNFYSDNSNSSMSVTSGEGE--GPRVRAGSIPGER
REG--GGVWRGSGIK-LSGHLLGGGAWRGKKRNLQPGPGETVG----LRCTRPQ-WSP-W
APAEPAGSSA--VSEE---QLDLLPILDLRQEMPSP-QVSKSF-----------LSLLF-
----QVLSVLLSLVGDVLVS--VYREVCSIRFLLTAVSLLSLFLAA----------LWWG
LLYLAPPLEHEPK------------EMLTLS--------EY----HERVRSQGQQLQQLQ
AELVK-------------LH-KEMSSVR-----------------------------PE-
-----------------------------RVAQLVFQ-RLSEDFVRKPDYALS-------
-----------------SVALGASIDL--EKTSQDYEDANTAYFWNRFSFWNYARPPTV-
ILEPDVFPGNCWAFEGDQGQVVIRLPGRVQLSDITLQHPPPT-VAHTRGANSAPRDFAVY
G-----------------L-----QVDD--ETEVFLGKFTF-NVEKSEIQ--TFHL--QN
DP--PAA------FPKVKIQ-------ILSNWGHPRFTCLYRV-RAHGVRTSEGAGDSAT
G--DAH------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------MKMIQFSARKDLIL-DAVFHSLE--------------------ENGIDGMKREE
-----------------------IL----QLTREAVE-KVMKHDTWLPSWALK-------
-----------------TM--GATIDV--ERTSKSYGGNRWL----SP-FFSSAKPPET-
ILQPDISAGNCWAFQGSRGHVVIRLPEKIWPTAFTLWHISKA-VSPSGEVSTAPREFVVS
G-----------------V-----DED-E-GEA-LLGSFIY-DVDGEIAQ--TFPV--QE
EP--RKA------FRQIKLE-------VRSNWGNAEYTCVYRA-DVHGSPEKN-------
------------------------------------------

------------------------------------------------------------
---------------------------------------------------MSRRSQRLT
---RYS-QGDDDGGSSSSGGSSVAGSQSTLFKDSPLRTLK-RKSS--NMKRPSPEPQLGP
SSDPHTSYYSES--LVRESYIGSPRAAFL------ARSA-LE-E-LHSDPDWGECSVLSR
GALLPPPPPEILLAVSPAVLAFPPQSTSLPRPHFSEALGGPEEPLVLPCTGDHLRVRKRR
GT--GGSESSRASGLV-GV-KATEDFLGSSSGYSSEDDYV--------------------
-----GYS-DADPQSSGSR---LQSVVSRVG--SLLW-----------------------
------MVATSPGRLFRLLYWWAGTTWYRLT-TAASLLDVFVLTRR--FS----SLKTF-
LWFMLLLLLLTCLTYGA--WYFYPYGLQTFHPALVSWWTAKD----SRREHEGWESRDSS
PH---FQAEQHVLSRV--HSLERRLEALAAEFSSNWQKEAMRLER-LELRQGTPAQGG--
------SGGLSHED-----------TLALLEG--L--VSRR------E-TALREDFRRET
A---------------------A-----RIQEELAA---LRAEHQQDSEDLFKKIVRASQ
ESEAHIQQLKSEW----Q--SMTQDAFRESSV--KELRRLEDQLASLQQELAALVQKQSS
VADEVGLLPQQIQAARD-------DVESQFPAWISEFL-AR----G---GGGRAGL-LQR
EEMQA-----QLRDLESKIL-THIAEMQG-----KSAREAAASLGLTLQKEGVIGVTEEQ
-----------------------VH----RIVKQALQ-RYSEDRIGLADYALE-------
-----------------SG--GASVIS--TRCSETYETKTALLSLFGIPLWYHSQSPRV-
ILQPDVYPGNCWAFQGPQGFAVVRLSARIRPTAVTLEHVPKA-LSPNSTISSAPKDFAVF
G-----------------F-----DEDLQ-QEGTLLGKFTYDQD-GEPIQ--TFHF--QA
PM--MAT------YQVVELR-------ILTNWGHPEYTCIYRF-RVHG------EPAH--
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------MS-------SVKEMT
KKKSELCILLLLIFLSA-LTGAYCGISLARVLWTEDFL-Q-------------------M
LPLQTAP-------RPMNSG-NSLTEETQ---------------GIENQRNGVSYLAEER
---------------------GTVMKDAQDLREAACV-MPKEKCFTKCDRALK-------
-----------------SA--GVSIDL--QRSSRSAWH-----CKV-AWFLCTQNVVET-
FEQLDMSPGYCWPLKASQSQVVFNLPTKVQPTAVTVQHSVETN---LWHVSSAPRDFAVF
G-----------------L-----DEEGE--KEALLGKFTY-DVRKEVTQ--TFQL--QT
ET--PRA------FWYIKLV-------VLNNWGNAGHTCIYRV-QVHGKRAGTNDIGQGH
V-----------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
M---------------------I-----FI---LCRLPRSWKII----------LSIIF-
--------------------------------------TTSFLLVG-------LQNHQWL
KEREFPQTFRELYAIIA-------EYGSRLSNYQARLR-MP----KEQLELLKKESQTLE
NNFREILILIEQIDVLKALL-RDMKDGMYNH---SWPAHRDAE-----QDQNSTGVLDE-
--------------------------EMSNLVHYVLK-KLRGDQVQMADYALK-------
-----------------SA--GASIIE--AGTSESYKNNKAKLHCYGLRFLNYEMPPDI-
ILQPDVHPGKCWAFPGSQGHILIKLARKIIPTAVTMEHISEK-VSPSGNTSSAPKEFSVY
-----------------GI-----MKKCE-GEEIFLGQFTY-NKTETTIQ--TFEL--QK
EV--SDS------LLCVKLK-------ILSNWGHPKYTCLYRF-RVHGTPNDHT------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------MRRSPRQ--------------
------------GSTASPHKH---TPNFYSDNS--SQSVTSRDSS--GH-RSAGLGPGKF
EGR--RTKGSSCGEPALTPGMPAGVPKAGSLRPKPTSRSHNGQ----TPRGAAT-VRG-G
A-SELAEPPV--VSEEQ-QQLDLLSTLDLRQEIPPP-RVSKSF-----------LSLLF-
----QVLSVLLSLVGGALVS--VYREVCSIRFLFTAVSLLGIFLAA----------LWWG
LLYLVPPLENEPKE------------MLTLS--------EY----HERVRSQGQQLQQLQ
AELHK-------------LH-KEMSSVRA--------------------------AHSE-
-----------------------------RVAKLVFQ-RLNEDFVRKPDYALS-------
-----------------SV--GASIDL--EKTSEDYEDTNTAYFWNRFSFWNYARPPSV-
ILEPDVFPGNCWAFEGDQGQVVIRLPGHVQLSDITLQHPPIS-VAHTGGANSAPRDFSVF
G-----------------L-----QVDD--ETEVFLGKFTF-DVQKSEIQ--TFHL--QN
DP--PSA------FPKVKIQ-------ILSNWGHPRFTCLYRV-RAHGVRTSEGMGESVS
G--ATGG-----------------------LH----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------MSGNGKLRQGAGSFLGGSD----DPSSSSSSSTSIPVLLPEH---
------------------------------------------------------------
R---------------------N-----PG---ANGLTRSWKVI----------LSIML-
--------------------------------------TLTFLLVG-------FRNHQWL
KETQFPQKYRQLYAVVA-------EYGTRLYDYQARMR-MP----RGQLELLKKESQALE
NNFREILLLIEQMDLLRALL-RDMKDGADHDS---GSRPGDVT-----QDQNGAEVPEE-
--------------------------EMFTLVNYVLK-KLREDQVQMADYALK-------
-----------------SA--GASIVE--SETSESYTNNNTKLYWHGIGLLNHEMPPDI-
ILQPDVHPGKCWAFPGSQGHILIRLARKIIPMSVTMEHISEK-VSPSRNTSSAPKEFSVH
-----------------GL-----MKRCE-GEEIFLGQFVY-NKTETTIQ--TFDL--QH
EI--SES------LLCVRLK-------ILSNWGHPNYTCLYRF-RVHGIPRDHT------
------------------------------------------

------------------------------------------------------------
---------------------------------------------------MSRRSQRLT
---RYS-QGDDDGS-SSSGGSSVAGSQSTLFKDSPLRTLK-RKSS--NMKRLSPAPQLGP
SSDAHTSYYSES--LVRESYIGT---AFP------PRSA-LE-E-LHGDADWG-------
---------------------------------------------------EDLRVRRRR
GT--GGSESSRASGLV-GR-KAAEDFLGSSSGYSSEDDYMEDSEG----GGLKVTEAEPV
SSFPAGYS-DADQQSSGSR---LWNAVSRAG--SLLW-----------------------
------MVATSPGRLFRLLYWWAGTTWYRLT-TAASLLDVFVLTRR--FS----SLKTF-
LWFLLPLLLLTCLTYGA--WYFYPYGLQTFHPALVSWWAAKD----SRRQDEGWESRDS-
SH---FQAEQRVMSRV--HSLERRLEALAAEFSSNWQKEAMRLER-LELRQGAPGQGG--
------GGGLSHED-----------TLALLEG--L--VSRR------E-AALKEDFRREA
A---------------------A-----RIQEELSA---LRAEHQQDSEDLFKKIVRASQ
ESEARIQQLKSEW----Q--SMTQESFRESSV--KELRRLEDQLAGLQQELAALALKQSL
VADEVGLLPQQIQAVRD-------DVESQFPAWISQFL-AR----G---GGGRVGL-LQR
EEMQA-----QLRELESKIL-THVAEMQG-----KSAREAAASLGMTLQKEGVIGVTEEQ
-----------------------VH----RIVKQALQ-RYSEDRIGLADYALE-------
-----------------SG--GASVIS--TRCSETYETKTALLSLFGIPLWYHSQSPRV-
ILQPDVHPGNCWAFQGPQGFAVVRLSARIRPTAVTLEHVPKA-LSPNSTISSAPKDFAIF
G-----------------F-----DEDLQ-QEGTLLGKFTYDQD-GEPIQ--TFHF--QA
PS--MAT------YQVVELR-------ILTNWGHPEYTCIYRF-R------VHGEPAH--
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------MP----KEQLELLKKESQTLE
NNFREILFLIEQIDVLKALL-RDMKAGTYNY---SWNVQGDTA-----QDQDSSEMLDE-
--------------------------EMSNLVHYVLK-KLRGDMVQMADYALK-------
-----------------SA--GASIIE--AGTSASYKNNKAKLYWHGIGFLNYEMPPDI-
ILQPDVHPGKCWAFPGSQGHILIKLARKITPTAVTMEHISEK-VSPSGNISSAPKEFSVY
-----------------GI-----AKKCE-GEEIFLGQFIY-NKTENTVQ--TFEL--QH
EV--SEP------LLCVNLK-------ILSNWGHPKYTCLYRF-RVHGVPTDHT------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MP----------------
--------------R---------------------------SSR----------SPV--
-----D-LCSITRG-----------CLNKFA----PLK--EVAPRSRNTCRITENTLSNA
--RDAFVLPV---------RIHA-PAPGLTQCLLAC--VSWITC----------L-ACFL
RTQVHQI----------LFNTCRCKLFIQKLM--EKTGVLVLCAFG-----------FWV
FSMHLPSKMEVWQDDS---------INSPL----QSLR-MY----QEKVRHHTGEIQDLR
GNMT-------------QLI-AKLQLMEA--------------------------MSDEQ
K-----------------------------MAQKIMK-MIQGDFIEKPDFALK-------
-----------------SI--GASIDF--EQTSATYNHDKARSYWNWIRLWNYAQPPDV-
ILEPNMTPGNCWAFSGDRGQVTIRLAQKVYLSNLTLQHIPKT-ISLSGSLDTAPKDFVIY
-----------------GM---E---G-SPREEVFLGAFQF-QP-ENIIQ--MFQL--QN
QP--VRA------FGAVKVK-------ISSNWGNPRFTCLYRV-RVHGSVTPPR------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MP----------------
------------------------------------------RSR----------NTG--
-----A-SCAPPED-----------LSHCARP--R----R-GNQRGH-------------
------------------------PANRTTEAPSAN--MTWLTC----------L-ACFL
RTQAQQV----------LLNTCRCKLLCQKLM--EKMGLLILCAFG-----------FWM
FSMHLPSKMEVWQDDS---------INGPL----QSLR-MY----QEKVRHHTGEIQDLR
GSMN-------------LLI-AKLQEMQA--------------------------MSDKQ
K-----------------------------MAQKIMK-MIHGDYIEKPDFALK-------
-----------------SI--GASIDF--EHTSATYNHDKARSYWNWIRLWNYAQPPDV-
ILEPNVTPGNCWAFAGDRGQVTIRLAQKVYLSNITLQHIPKT-ISLSGSLDTAPKDFVIY
-----------------GM---E---S-PPREEVFLGAFQF-QP-ENTIQ--MFPL--QN
QP--PRG------FAAVKVK-------ISSNWGNPRFTCLYRV-RVHGSVTPPRDSNLE-
S-----------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------EH----QERLRSHGQQLQQLQ
AELNK-------------LR-KEVARVRK--------------------------AHSE-
-----------------------------RVAKLVFQ-RLNEDFVQKPDYALS-------
-----------------SV--GATIDL--EKTSHDYEDTNMAYFWNRFSFWNYARPPTV-
ILEPDVFPGNCWAFQGHQGQVVIRLAGRVQLSDITLQHPPPS-VAHTEDASSAPRDFAVF
G-----------------L-----QVDD--KTEVFLGRFTF-DVKKFAIQ--TFHL--QN
DS--PSA------FPKVKIQ-------ILSNWGHPRFTCLYRV-RAHGLRISEGEGSA-T
G--ATGG-----------------------PH----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MSF-
SLLPDISPGSCWAFQGSQGHVVIRLPEKIQPRAFTIWHISRA-VSPCGEVSSAPEEFAVS
V-----------------S-----LCL-----------LL--LLEGPRAR--GRAL--PE
MS-----------FWW--------------------------------------------
------------------------------------------

------------------------------------------------------------
---------------------------------------------------MSRRSQRLT
---RYS-QGDDDGS-SSSGGSSVTGSQSTLFKDSPLRTLR-RKSS--NMKRLSPAPQLGP
SSDAHTSYYSES--MVRESYIGSPRAAA------------LE-D-LHSDPYWS-------
---------------------------------------------------EDLRVRRRR
GT--GGTESSKVNGLA-ES-KVSEDFLGSSSGYSSEDDYVEDS-----------------
---------EGRRDSLH------ITRLERDG--QLSWFPFLFRCR----------LLRHR
PAEEQCFMVTFSGRLFGLLYWWFGTTWYRLT-TAASLLDVFVLTRR--FS----SLKTF-
LRFLLLLLLLTCLTYGA--WYFYPYGLQTLHPAVVSWWAAKD----SRRQHEGWDSRDS-
PH---FQAEQHILSRV--HSLERRLEALAAEFSSNWQKEALRLER-LELWQGAAGHGG--
------SGGLSHED-----------TLALLEG--L--VNRR------E-AALKEDLRRDA
A---------------------S-----RLQEELAT---LRAEHQQDAEDLFKKIVQASQ
ESEARMHQLKSEW----Q--RMTQESFRESSV--KELGRLEDQLAGLRQELAALTLKQSS
VADEVGLLPQQIQAVRD-------DVESQFPAWISQFL-LR----G---GGTRTGL-LQR
EEMQA-----QLQELESKIL-AHVAQMQG-----KSAREAAASLGLTLQKEGVIGVTEEQ
-----------------------VH----RIVKQALQ-RYSEDRIGMVDYALE-------
-----------------SG--GASVIS--TRCSETYETKTALLSLFGIPLWYHSQSPRV-
ILQPDVHPGNCWAFQGPQGFAVVRLSARIRPTAVTLEHVPKA-LSPNSTISSAPKDFAIF
G-----------------F-----DEDLQ-QEGTLLGKFTYDQD-GEPIQ--TFHF--QA
PQ--MAT------YQVVELR-------ILTNWGHPEYTCIYRF-RVHGEPAH--------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------ME------R
V---------------------R-----EW---LNQEYFSWKII----------LSVMV-
--------------------------------------LATFIFIG-------LHDSEKL
RRTGLSHIPRQLYELSA-------DYGSKLYNYQTRIR-LS----KSKMELLKKGSHYLE
NNSQEILSLIKQINILKAIL-KDIKNQLDNY---ILNANTDAF-----GEQDDSYITDE-
--------------------------EMMTLVNYVLK-KLREDQVQMADYALK-------
-----------------SA--GASIVE--AGTSESYKNDKAKLYWHGIGFLSYEMPPDV-
ILQPDVHPGKCWAFPGSKGHTIIKLARKIIPTAVTMEHISEK-ISPSGNTHSAPKNFSVY
-----------------GL-----KDECK-GEEIFLGQFMY-NKKGTTVQ--TFQL--QN
GV--SES------FPYVKLK-------ILKNWGHPKYTCLYRF-RVHGKPGNDTLGVP--
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------MSGKMKARMAAIFFRDCSE----EASGSAS----GDALLSEH---
------------------------------------------------------------
E---------------------N-----PD---ANGVTRSRKII----------LSTMF-
--------------------------------------TLTFLIAG-------FLSHQWL
KETEDPQKSRQLYTIIA-------EYGSRLYKYQARLR-MS----KEQLELLKKESQTLE
NNFREILFLIEQIDVLKALL-RDMKDGMDNNH--SWSTHGDPA-----EDPDHTE-----
--------------------------EMSNLVNYVLK-KLREDKVQMADYALK-------
-----------------SA--GASIIE--AGTSESYKNNKAKLYWHGIGFLNHEMPPDT-
ILQPDVYPGKCWAFPGSQGHTLIKLARKIIPTAVTMEHISEK-VSPSGNISSAPKEFSVY
-----------------GI-----TKKCD-GEEIFLGQFIY-NKTGTTIQ--TFEL--QH
AV--SEY------LLCVKLN-------IFSNWGHPNYTCLYRF-RVHGTPGTHI------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------RFSSLK--TFL------------------------
--------------------WFL------LL--------LLLLTCLTYXXX---------
XXXXXXXX--------------------XXXXXXXXXXXXXX----XXXXXXXXXXXXXX
XX---XXAEQHILSRM--HTLERRLEALAAEFSSNWQKEAMRLER-LELRQGATGQGGG-
---GGGGGSLSHED-----------TLTLLEG--L--VSRC------E-AALKEDFRRDT
A---------------------A-----RIQXXXXX---XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXX-XX---XXXXXXXXXX--XXXXXXX--XXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXX-------XXXXXXXXXXXXXX-XR----G---GGTRAGL-LQR
EEMEA-----QLQELERKIL-AHVAEMQG-----QSAREAAASLGLTLQREGVIGVTEAQ
-----------------------VH----RIVKQALQ-RYSEDRIGMVDYALE-------
-----------------SG--GASVIS--TRCSETYETKTALLSLFGIPLWYHSQSPRV-
ILQPDVHPGNCWAFQGPQGFAVVRLSARIRPTAVTLEHVPKA-LSPNSTISSAPKDFAIF
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------MSGRPKTRRCPRVIRTHFE----ETVGSSN---MNSNMLSQHR--
NPDPN-------------------------------------------------------
-----------------------------------WLIRSRKIS----------ISMIL-
--------------------------------------ILTFILIXX-------XXXXXX
XXXXXXXXXXXXXXXX-------XXXXXXXXXXXXXXX-XX----XXXXXXXXRESQILE
NNFREILILT-EQI-------------------------------------------DSL
---------------------KALLREMKNGV--YNQ-SWNEDPIGKQDKDXXXXXXXXX
XXXXXXXXXXXXXXXXXXX--XXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-
XXXPDVHPGKCWAFPGSRGHTLVKLARRIVPTAVTVEHISLR-VSPSGNISSXXXXXXXX
G-----------------I-----SKECN-GEEIFLGQFIY-NKKETTVQ--TFEL--QH
EA--SES------LLCVKLK-------ILSNWGHPNYTCLYRF-RVHGNPVNQI------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MP----------------
--------------R---------------------------SSR----------SPG--
-----DPGAP-LED-----------VAHNPRP--R----R-IVQRGRNTSRTVEDTSSNM
N-D-NFPLPV---------RINA-QALGLTQCMLRC--VSWFTC----------F-ACSL
RTQAQQV----------LFNTCRCKLLCQKLM--EKTGILLLCAFG-----------FWM
FSIHLPSKMKVWQDDS---------INGPL----QSL-RLY----QEKVRHHSGEIQDLR
GSMN-------------LLI-AKLQEMEA--------------------------MSDEQ
K-----------------------------VAQKIMK-MIHGDYIEKPDFALK-------
-----------------ST--GASIDF--EHTSATYNHEKAHSYWNWIQLWNYAQPPDV-
ILEPNVTPGNCWAFEGNRGQVTIQLAQKVYLSNLTLQHIPKT-ISPSGSLDTAPKDFVIY
-----------------GM---E---G-SPKEEVFLGAFQF-QP-ESIIQ--MFPL--QN
QP--ARA------FGAVKVK-------ISSNWGNPAFTCLYRV-RVHGSVAPPGEQPHQN
PYPERD------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------MRRSSRP--------------
------------GSASSSRKH---TPNFFSENSSMSIT--SEDSK--GL-RSAGTGPGEP
EGR--RARGPSCGEPALSAGVPGGTTWAGSSQQKPAPRSHNWQ----TAC-GAA-TVR-G
GASEPTGSPV--VSEE---PLDLLPTLDLRQEMPPP-RVFKSF-----------LSLLF-
----QGLSVLLSLAGDVLVS--MYREVCSIRFLFTAVSLLSLFLSA----------FWLG
LLYLVSPLENEPK------------EMLTLS--------EY----HERVRSQGQQLQQLQ
AELDK-------------LH-KEVSTVRA--------------------------ANSE-
-----------------------------RVAKLVFQ-RLNEDFVRKPDYALS-------
-----------------SV--GASIDL--RKTSHDYADRNTAYFWNRFSFWNYARPPTV-
ILEPHVFPGNCWAFEGDQGQVVIQLPGRVQLSDITLQHPPPS-VEHTGGANSAPRDFAVF
G-----------------L-----QVDD--ETEVSLGKFTF-DVEKSEIQ--TFHL--QN
DP--PAA------FPKVKIQ-------ILSNWGHPHFTCLYRV-RAHGVRTSEGAEGSAT
G--GPH------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------PAL-
CFQLDISPGYCWPVKTSQSQMVFNLPTEVQPTAVTVQHTVDTT---LWHISSAPRDFAVF
G-----------------L-----DEKGE--NKVLLGKFTY-DIREELSQ--TFEL--QT
ET--PRA------FWHIKLS-------VLNNWGNAGHTCIYRV-QVHGKSAGIK------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MP----------------
------------------------------------------RAR----------NTG--
-----D-SCALPED-----------TSHNARH--R----R-GVQRSHTTSRPTEAPAANM
N-D-ALLLPL---------RINT-PGLSLTQFILGY--MSWLTC----------L-ACFL
RTQAQQV----------LLNTFRCKLLCQKLM--EKMGLLVLCAFG-----------FWI
FSMHLPSKLEVWQVSV-----------SPL----Q-AL-MY----QEKVRHHTGEIQDLR
GSMN-------------QLI-AKLQEMEA--------------------------MSDEQ
K-----------------------------MAQKIMK-MIQGDYIEKPDFALK-------
-----------------SI--GASIDF--EHTSATYNHDKARSYWNWIRLWNYAQPPDV-
ILEPNVTPGNCWAFAGDRGQVTIRLAQKVYLSNITLQHIPKT-ISLSGSLDTAPKDFVIY
-----------------GM---E---S-PPREEVFLGAFQF-QP-ENTIQ--MFPL--QN
QP--PRG------FAAVKVK-------ISSNWGNSRFTCLYRV-RVHGSVTPPRDSHLE-
PLS---------------------------------------

------------------------------------------------------------
------------------------LAQPQASPALLSLPRLSLGEGSPSHLIMSRRSQRLT
---RYS-QGDDDGGS-SSGGSSVAGSQSTLFKDSPFRTVK-RKPS--STKRLSPAPQLGP
SDS--HTYYSES--VVRESYYGSPRAASL------ARSSILD-DQLHSDRYWS-------
---------------------------------------------------EDLPVRRRR
GT--GDTESSKINGLV-GA-KLSEDFPGSSSGYSSEDDYV--------------------
-----GYS-QAAQQGSGSR---LRGAVSRAG--SFFW-----------------------
------TVVTFPGRLFGLLYWWVGTTWYRLT-TAASLLDVFVLT--RRFS----SLKAF-
LWFLLLLLLLTGLTYGQGLENFYPYGLHTVHPTLVSWWAAKG----SSQQREVWEPRDSQ
PR---LQAEQRILSRV--HSLERRLEALAAEFSSAWQKEAMRLER-LELRQGAAGEG---
-----GGRGLSQED-----------TLELLEG--L--VSRR------E-AALKEDFRRDT
A---------------------A-----RIQEELGA---LRAEHQQDAEDLFKKIVRASQ
ESEDRLQQLKSEW----H--RMTQESFRENSM--KELGRLEGQLAGLRQELAALALKQSS
VADQVGLLPQQLQAMRD-------DVESQFPAWVSQFL-LQ----G---GGARSGL-LQR
EEMQA-----RLQELEGKIL-RHVAEMQG-----KSAKEAVASMGLRLQKEGVIGVTEEE
-----------------------VQ----RIVNQALK-RYSEDRIGMVDYALE-------
-----------------SGGSGASVIS--TRCSETYETKTALLSLFGIPLWYHSQSPRV-
ILQPDVHPGNCWAFQGPQGFAVVRLSARIRPTAVTLEHVPKS-LSPNSTISSAPKDFAVF
G-----------------F-----DEDLQ-QEGTPLGQFTYNQD-GEPIQ--TFYF--QD
PK--MAT------YQVVELR-------ILTNWGHPEYTCIYRF-RVHGEPAH--------
------------------------------------------

------------------------------------------------------------
---------------------------------------------------MSRRSQRLT
---RYS-QDDND-GSSSSGASSVAGSQSTLFKDSPLRTLK-RKSS--NMKRLSPAPQLGP
SSDSHTSYYSES--VVRESYIGSPRAASL------ARSALLD-DRLHSEPYWS-------
---------------------------------------------------GDLRGRRRR
GT--GGSESSKANGLTTES-KVSEDFFGSSSGYSSEDDF---------------------
----AGYM-ESDQHGSGSG---LRSAASRAG--SFVW-----------------------
------TLVTFPGRLFGLLYWWVGTTWYRLT-TAASLLDVFVLTRSRHFS---LNLKTF-
LWFLLFLLLLTVLTYGA--WYFYPFGLHTLQPTLASWWAAKE----SKRQPEVWESRDAS
PH---FQAEQRILSRV--YSLERRLEALAAEFSSNWQKEAIRLER-LELRQGATGHGG--
------GSGLSHED-----------TLTLLEG--L--VSRR------E-AALKEDLRRDT
M---------------------S-----RIQEELAT---LRAEHHQDSEDLFRKIVQASQ
ESEAHVQQLKTEW----Q--RMTQEAFQESSV--KELGQLEAQLASLRQELAALTLRQNS
VADEVGLLPQKIQAARA-------DVESQFPDWVSRFL-LR----D---KGASSGL-LQR
DELHA-----QLQELESKIL-ASMAEMQG-----KSAREAAASLGQTLQKEGVVGVTEEQ
-----------------------VH----QIVKQALQ-RYSEDRIGMVDYALE-------
-----------------SG--GASVIS--TRCSETYETKTALLSLFGIPLWYHSQSPRV-
ILQPDVHPGNCWAFQGPQGFAVVRLSARIRPTAVTLEHVPKA-LSPNSTISSAPKDFAIF
G-----------------F-----DEDLQ-QEGTLLGTFAYDQD-GEPIQ--TFYF--QT
SK--MAT------YQVVELR-------ILTNWGHPEYTCIYRF-RVHGEPAH--------
------------------------------------------

------------------------------------------------------------
---------------------------------------------------MSRRSQRLT
---RYS-QDDND-GSSSSGASSVAGSQSSL-------TLK-RKSS--SMKRLSPAPQLGP
SSDSHTSYYSES--VVRESYIGSPRAASL------ARSALLD-DRLHSEPYWS-------
---------------------------------------------------GDLRGRRRR
GT--GGSESSKANGLTTES-KVSEDFFGSSSGYSSEDDF---------------------
----AGYT-DSSQHGSGSG---LRSAASRAG--SFVW-----------------------
------TLVTFPGRLFGLLYWWVGTTWYRLT-TAASLLDVFVLTRSRHFS---LNLKTF-
LWFLLFLLLLTGLTYGA--WYFYPFGLHTLQPTLASWWAAKE----SRRQPEVWESRDAS
LH---SQAEQRILSRV--HSLERRLEALASEFSSNWQKEAMRLER-LELRQGATGHGG--
------SSGLSHED-----------TLSLLEG--L--VNRR------E-AALKEDLRRET
V---------------------A-----RIQEDLAT---LRAEHHQDTEDLFKKIVQASQ
VSGLALPYLPSSG----V--RMTQEAFQESSE--KELGRLEAQLASLRQELAALTLRQNS
VADEVGLLPQKIQAARA-------DVESQFPDWVSQFL-LQ----D---RGARSGL-LQR
DELHA-----QLQELESKIL-VSMAEMQG-----KSAREAAASLGQTLQKEGVVGVTEEQ
-----------------------VH----LIVKQALQ-RYSEDRIGMVDYALE-------
-----------------SG--GASVIS--TRCSETYETKTALLSLFGIPLWYHSQSPRV-
ILQPDVHPGNCWAFQGPQGFAVVRLSARIRPTAVTLEHVPKA-LSPNSTISSAPKDFAIF
G-----------------F-----DEDLQ-QEGTLLGTFAYDQD-GDPIQ--TFYF--QA
SK--MAT------YQVVELR-------ILTNWGHPEYTCIYRF-RVHGEPAH--------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----PTGSPL--VSEE---PLHLLPTLDLRPEMPPS-RMFKSF-----------LSLLF-
----QVLSVLLSLAGDVLVS--MYREVCSIRFLFTAVSLLSLFLAA----------IWLG
LLYLVSPLENEPK------------EMLTLS--------EY----HERVRSQGQQLQQLQ
AKLDK-------------LH-KEVSTVRA--------------------------ANSE-
-----------------------------RVAKLVFQ-RLNEDFVRKPDYALS-------
-----------------SV--GASIDL--QKTSHDYADRNTAYFWNRFSFWNYARPPTV-
ILEPHVFPGNCWAFEGDQGQVVIQLPGRVQLSDITLQHPPPS-VEHTGGANSAPRDFAVF
G-----------------L-----QVDD--ETEVFLGKFTF-DVEKSEIQ--TFHL--QN
DP--PAA------FPKVKIQ-------ILSNWGHPRFTCLYRV-RAHGVRTSEGAEGSAT
G--GPH------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MP----------------
--------------R---------------------------TAR----------NPG--
-----D-QCSIHED-----------VALRDPR--P----K-------------------T
A-S-K-------------------SSQENRMEDATS--HSWFTC----------L-ACFL
RTQAQQV----------LFNTCRCKMLCQKLM--EKTGVLVLCAVG-----------FWM
CSMHLPSRVEVWQDDS---------INSPL----QSLR-LY----QEKVRHHTGEIQDLR
GSMN-------------QLI-AKLREMEA--------------------------MSDEQ
K-----------------------------MAQKIMK-MIQGDYIEKPDFALK-------
-----------------SI--GASIDF--DHTSATYNHEKARSYWNWIRLWNYAQPPDV-
ILEPNVTPGNCWAFAGDRGQVTIRLAQKVYLSNLTLQHIPKT-ISLSGSLDTAPKDFVVY
-----------------GM---E---N-PPSEEVFLGAFQF-QP-ENTIH--IFSL--QN
EP--PRA------FGAVKVK-------ISSNWGNPRFTCLYRV-RVHGSVTPPEEPHP-Q
PLP---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------MRRSSRP--------------
------------GSASSSRKH---TPNFFSENSSMSIT--SEDSK--GL-RSAEPGPGEP
EGR--RARGPSCGEPALSAGVPGGTTWAGSSQQKPAPRSHNWQ----TAC-GAA-TVR-G
GASEPTGSPV--VSEE---PLDLLPTLDLRQEMPPP-RVFKSF-----------LSLLF-
----QGLSVLLSLAGDVLVS--MYREVCSIRFLFTAVSLLSLFLSA----------FWLG
LLYLVSPLENEPK------------EMLTLS--------EY----HERVRSQGQQLQQLQ
AELDK-------------LH-KEVSTVRA--------------------------ANSE-
-----------------------------RVAKLVFQ-RLNEDFVRKPDYALS-------
-----------------SV--GASIDL--QKTSHDYADRNTAYFWNRFSFWNYARPPTV-
ILEPHVFPGNCWAFEGDQGQVVIQLPGRVQLSDITLQHPPPS-VEHTGGANSAPRDFAVF
G-----------------L-----QVYD--ETEVSLGKFTF-DVEKSEIQ--TFHL--QN
DP--PAA------FPKVKIQ-------ILSNWGHPRFTCLYRV-RAHGVRTSEGAEGSAQ
G--PH-------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------MLTQSWKIL----------LSTVC-
--------------------------------------ISTFLLVG-------LLNHQWL
TETEFPEKLRQLYTVIA-------KYGYRLHNYQARLL-MS----KEQQELLKKERQTLE
NYSRQILFLNEQIDVLEALL-KDMKDGAHNH---SLPVHRKAV-----QDQAMDDVLDE-
--------------------------EISNLVHYVLK-KYRGDQIQLADYALK-------
-----------------SA--GASIIE--AGTSESYKNNKAKLYWHGIAIFNYETPPDM-
ILQPDVHPGKCWAFPGSQGHILIKLARKIIPTAVTMEHISEK-VSPSGNISSAPKEFAVY
-----------------GV-----MKKCE-GEEIFLGQFIY-NKMEATIQ--TFEL--QN
EA--SES------LLCVKLQ-------ILSNWGHPKYTCLYRF-RVHGIPSDYT------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------MSGKTKARRAAMLSRRCSE----DASRSAS----GNALLSED---
------------------------------------------------------------
E---------------------N-----PD---ANGVTRSWKII----------LSTML-
--------------------------------------TLTFLLVG-------LLNYQWL
KETDVPQKSRQLYAIIA-------EYGSRLYKYQARLH-MP----KEQLELLKKESQTLE
NNFRQILFLIEQIDVLKALL-RDMKDGTDNNH--NWNTHGDPV-----EDPDHTE-----
--------------------------EMSNLVNYVLK-KLREDQVQMADYALK-------
-----------------SA--GASIIE--AGTSESYKNNKAKLYWHGIGFLNHEMPPDI-
ILQPDVYPGKCWAFPGSQGHTLIKLATKIIPTAVTMEHISEK-VSPSGNIYSAPKEFSVY
-----------------GI-----TKKCE-GEEIFLGQFIY-NKTGTTVQ--TFEL--QH
AV--SEY------LLCVKLN-------IFSNWGHPKYTCLYRF-RVHGTPGKHI------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MP----------------
--------------R---------------------------SSR----------SPV--
-----D-QCDLPED-----------A---------RPR--RVIPRSRNTCRITEDALSNS
--NDAFVLPI---------RIHP-PAPGLTQCILAC--ISWITC----------L-ACFL
RTQAHQV----------LFNTCRCKLLFQKLM--EKTGVLVLCAFG-----------FWV
FSMHLPSKMEVWQDDS---------INSPL----QSLR-MY----QEKVRHHTGEIQDLR
GNMT-------------LLI-AKLQLMEA--------------------------MSDEQ
K-----------------------------MAQKIMK-MIQGDYIEKPDFALK-------
-----------------SI--GASIDF--EQTSATYNHDKARSYWNWIRLWNYAQPPDV-
ILEPNMTPGNCWAFSGDRGQVTIRMAQKVYLSNLTLQHIPKT-ISLSGSLDTAPKDFVVY
-----------------GM---E---G-SPREEVFLGAFQF-QP-ENIIQ--MFQL--QN
QP--ARA------FGAVKVK-------ISSNWGNPRFTCLYRV-RVHGSVTPPRQP----
------------------------------------------

------------------------------------------------------------
---------------------------------------------------MSRRSQRLT
---RYS-QDDNDCGSSSSGASSVAGSQGTVFKDSPLRSLK-RKSS--NMKRLSPAPQLGP
SSDSHTSYYSES--VVRESYIGSPRAVSL------ARSALLD-DHLHSEPYWS-------
---------------------------------------------------GDLRGRRRR
GT--GGSESSKVNGLAAEG-KASEDFFGSSSGYSSEDDL---------------------
----AGYT-DSDQHSSGSG---LRSAASRAG--SFVW-----------------------
------TLVTFPGRLFGLLYWWVGTTWYRLT-TAASLLDVFVLTRSRHFS---LNLKSF-
LWFLLLLLLLTGLTYGA--WHFYPLGLQTLQPAVVSWWAAKE----SRKQPEAWESRDTS
PH---FQAEQRVLSRV--HSLERRLEALAADFSSNWQKEAIRLER-LELRQGAAGHGG--
------GSSLSHED-----------ALSLLEG--L--VSRR------E-AALKEDLRRDT
V---------------------A-----HIQEELAT---LRAEHHQDSEDLFKKIIQASQ
ESEARIQQLKTEW----Q--SMTQEAFQESSV--KELGRLEAQLASLRQELAALTQKQNS
VADEVGLLPQKIQAARA-------DVESQFPDWITQFL-LG----D---RGVRSGL-LQR
DEMHA-----QLQQLEDKIL-AKMAEMQG-----KSAREAAASLGQILQKEGVVGVTEEQ
-----------------------VH----RIVKQALQ-RYSEDRIGMVDYALE-------
-----------------SG--GASVIS--TRCSETYETKTALLSLFGIPLWYHSQSPRV-
ILQPDVHPGNCWAFQGPQGFAVVRLSARIRPTAVTLEHVPKA-LSPNSTISSAPKDFAIF
G-----------------F-----DEDLQ-QEGTLLGTFAYDQD-GEPIQ--TFYF--QA
SK--MAT------YQVVELR-------ILTNWGHPEYTCIYRF-RVHGEPAH--------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------MRRSPRP--------------
------------GSATSPHKH---TPNFYSDNSNSSVSVTSGDSS--GH-RSAG--PGEP
EGR--RARGSSCGEPALSAGVPGGTTWAGSSRQKPAPGSHNGP----IEPGRAE-GGG-G
A-QEPAGSPV--VSEE---QLDLLSTLDLRQEIPPP-RVSKNF-----------LSLLL-
----QVLSVLLSLVGDVLVI--VYREVCSIRFLLTAVSLLSLFLAA----------LWWG
LLYLVPPSENEPKE------------MLTLS--------EY----HERVRSQGQQLQQLQ
AELNK-------------LH-KEVSSVRA--------------------------ANSE-
-----------------------------RVAKIVFQ-RLNEDFVRKPDYALS-------
-----------------SV--GASIDL--EKTSHDYEDANTAYFWNRFSFWNYARPPTV-
ILEPDVFPGNCWAFEGDQGQVVIRLPGRVQLSDITLQHPPPS-VAHSGGANSAPRDFAVY
G-----------------L-----QVDD--ETEVFLGKFTF-DVEKSEIQ--TFHL--QN
DP--PNA------FPKVKIQ-------ILSNWGHPRFTCLYRV-RAHGMRISEGAGDSAT
G--ERH------------------------------------

------------------------------------------------------------
---------------------------------------------------MSRRSQRLT
---RYSQGGDDGDNSSSSGGSSATGSQSTLYKDSPFRSLK-KKSSSSGTKRLSPAPQLGP
ASDTHTSYYSES--VVRESSLAR--------------SSL---TDLRSEPYWS-------
---------------------------------------------------EDLRVRRRR
GT--GGTDSSKVNGLSEGAAAVSEDFLGSSSGYSSEDDFM--------------------
-----GYS-DTDPRSSSSR---LRGAVSGVG--SFLWSVLIFSX----------------
-------------XXXXXXXXXIGTT-YPLT-TA-ASLDVFVLPR--RFS----SLKTF-
LWFLLLLLFLTGLTYGA--WYFYPYGLQTVHPAVVSWWAAKD----SRRQQEVWESRDTA
AH---SQAEQRLLSHV--HSLERRLEALAAEFSSTWQKEAMRLER-LELRQGAASQGSD-
----SGGGGLSQED-----------TLALLDG--L--VSRR------E-ATLKEDLRRDT
T---------------------A-----RMQEELAT---LRAEHHRDVEDLFHKIVKAAQ
ESEDRVQELKVEW----Q--RTAQEVLRESSV--KELGRLEGQLATLQHELAALALKQSS
VEDQVGLLPQKIQAVRD-------EVESQAPAWITEFL-QG----G---GATRSGL-LER
EELQA-----QLRELEGKIL-AHMTETQG-----KSAREAAASLSLTLQKEGVIGVTEEQ
-----------------------VH----RIVKQALQ-RYSEDRIGMVDYALE-------
-----------------SG--GASVIS--TRCSETYETKTALLSLFGIPLWYHSQSPRV-
ILQPDVHPGNCWAFQGPQGFAVVRLSARIRPTAVTLEHVPKA-LSPNSTISSAPKDFAVF
G-----------------F-----DEDLQ-QEGTLLGKFTYDQD-GEPIQ--TFYF--QA
PP--VAS------YQVVELR-------ILTNWGHPEYTCIYRF-RVHGEPAH--------
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MP----------------
--------------R---------------------------HSR----------SPR--
-----D-LGDPPED-----------VAHTCRD--ARPR--RVLQRGRNTCRTPEEPSPNR
--NDSFLLPI---------RINA-TAPGLTQCMLGC--MSWITC----------L-ACFL
RTQAHQV----------LFNTCRCKLLFQKLM--EKTGVLVLCVFG-----------FWV
FSVHLPSQVQVWQDDS---------ISTPL----QSLR-MY----QEKVRHHTGEIQDLR
GSMN-------------QLI-AKLQEMEA--------------------------MSDEQ
K-----------------------------MAQKIMK-MIQGDYIEKPDFALK-------
-----------------SI--GASIDF--EQTSATYNHDKARSYWNWIRLWNYAQPPDGR
FLEPNVTPGNCWAFSGDRGQVTIQLAQKVYLSNLTLQHIPRT-ISLSGSLDTAPKDFVIY
-----------------GM---E---G-SPREEVFLGAFQF-QP-ENIIQ--TFQL--QN
QP--ART------FDAVKVK-------ISSNWGNPRFTCLYRV-RVHGSVTPPREQPS--
------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MP----------------
--------------R---------------------------FSR----------NPG--
-----D-PCVLPED-----------VVYNARP--R-----RGNQRNRNPCRLAEEPTAQR
--NDGALLRA---------RINT-PAVSLTHSVLEC--VSWFNC----------L-ACFL
RTQTQQV----------LFNTCRYKAICQKFM--EKTGILVLCALG-----------FWV
FSVHIPSKMEVWQDDS---------INSPL----QSLR-LY----QEKVRHHTGEIQDLR
GSVN-------------QLI-AKLKEMEA--------------------------MSDEQ
K-----------------------------LAQKIMK-MIQGDYIEKPDFALK-------
-----------------SI--GATIDF--EHTSPTYNHNKARSYWNWIRLWNYAQPPDV-
ILEPNMTPGNCWAFEGDRGQVSIQLAQKVYLSNLTLQHIPKT-ISLSGSLDTAPKDFVVY
-----------------GM---E---S-SPREEVFLGAFQF-QP-ENIIQ--TFAL--QN
QQ--LRA------FNAVKVK-------ISSNWGNPRFTCLYRV-RVHGSVAPPPRNLP--
------------------------------------------

------------------------------------------------------------
---------------------------------------------------MSRRSQRLT
---RYS-QGDDDG-SSSSGGSSVAGSRSALFRDGPLRTVK-RKSS--NMKRLSPAPQLGP
SSDAHTSYYSES--VVRESYIGSPRAASL------ARSALLD-DHLHSEPYWS-------
---------------------------------------------------GDLRVRRRR
GT--GGTESSQVNGLA-ES-KVSEDFLGSSSGYSSEDDF---------------------
----VGYS-DTDQHSSGSR---LRSAISQAG--SFVW-----------------------
------TVVTFPGRIFGLLYWWVGTTWYRLT-TAASLLDVFVLTRR--FS----SLRTF-
LWFLLLLLLLTGLTYGA--WYFYPYGLQTFHPAVVSWWAAKD----SRRQPEVWDSRGSS
PQ---FQAEQRILSQV--HSLERRLEALAAEFSSNWQKEAIRLER-LELRQGTTGQGG--
------SSGLSHED-----------TLALLEG--L--VSRR------E-AALKEDIRRDT
A---------------------T-----LLQEELVT---LRAEHHQDSEDLFKKIVQASQ
ESEAHIQQLRSEW----Q--RMTQEAFQEKAM--KELGRLEAQLASLRQELAAMSLKQSI
VADEVDLLPQKIQAARD-------DVESQFPAWVSQFL-LR----G---GGTRAGL-LQR
EEMQV-----QLQELESKIL-SHMAEMQG-----KSAREAVASLGLTLQKEGMVGVTEEQ
-----------------------VH----RIVKQALQ-RYSEDRIGMVDYALE-------
-----------------SG--GASVIS--TRCSETYETKTALLSLFGIPLWYHSQSPRV-
ILQPDVHPGNCWAFQGPQGFAVVRLSARIRPTAVTLEHVPKA-LSPNSTISSAPKDFAIF
G-----------------F-----DEDLQ-QEGTLLGTFTYDQD-GEPIQ--TFYF--QA
TK--MAT------YQVVELR-------ILTNWGHPEYTCIYRF-RVHGEPAH--------
------------------------------------------

Query Results

"ENSGT00390000011587_1"

ENSGT00390000011587_1