Query Results 

--------------------------------------------------MSVAKSTEGP
QGAVAIKLDLMSPPESAK---KLENKDST-FLDE--S-PSESP-----------------
GSKKTKG

PF01490 // ENSGT00390000011245_0_Domain_1 (128, 564)

ITGFQALVHLVKGNMGTGILGLPLAVKNAGILMGPLSLLVMGFVACHCMHL--
LVKCAQ--RF-------CKR----------------------------------------
-----------------LNKPFMDYG--DTVMHGLEANPSAWLRNH--AHWGRHIVSFFL
IV---------------------------------------------------------T
QLGFCCVYIVFLADNLKQVVEAVNSTTNNCHSNET-V-ILTPTMDSRLYMLSFLPFLVLL
VLIRNLRILTIFSMLANISMLVSLVIITQYISQEI----PDPSRLPLV------------
ASWKTYPLFFGTAIFSFESIGVV------LPLENKMKDARHFPAILSLGLSIIT--ALYI
GIGALGYLRFGDDIKASISLNLPNC-----------------------------------
-------------------------------LLAILIPRLDLVLALVGSVSSSALALIIP
PLLEVTTFYSEGMS-PLTIFKDALISILGFVGFVVGTYQALEELLKSEDSLPFSNST---
TFIQ-----------------------

--------------------------------------------------MPVTKSAGGP
QGAVDLKLDLRYPPKSAK---RLHSKDSS-FWDG--H-PSESP-----------------
GLEKTT

PF01490 // ENSGT00390000011245_0_Domain_1 (127, 452)

GITAFQTLVHLVKGNMGTGILGLPLAVKNAGILMGPLSLLAMGFIACHCMHI--
LVKCAR--RF-------CHR----------------------------------------
-----------------LNKPFMDYG--DTVLHGLEASPSAWLRSH--AHWGRHIVSFFL
IV---------------------------------------------------------T
QLGFCCVYIVFLADNLKQVVEAVNGTTNNCHYNET-V-ILTPTMDSRLYMLAFLPFLVLL
VLIRNLRVLTVFSMLANISMLVSLIIITQYIAQVSAHHTPDPSSGQRLFSRYLPRASPEG
RYVPDSPAYYHCTIFSAKVS---------------------LRSLLLLGISSFILLLQYL
SNSGLRKKLYSV-RKTS-------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------

--------------------------------------------------MPVTKSVESP
PGTGALKLNLMSSPENAK---KLQNKDST-YVEE--H-SSELR-----------------
CSEKTK

PF01490 // ENSGT00390000011245_0_Domain_1 (127, 700)

GITWLQTLIHLVKGNMGTGILGLPLALKNSGLLLGPLSLLAMGIVACHCMHM--
LVKCAR--HF-------CHR----------------------------------------
-----------------FNKPFMDYG--DTVMHALEASPRTWLRSH--AHWGRHIVSFFL
IV---------------------------------------------------------T
QLGFCCVYIVFLADNLKQVVEAVNVTTNNCHHNET-V-LLTPTVDSRLYMLAFLPLLVLL
ALIRNLRVLSIFSMLANISMLVSLVIITQYIAWGI----PHPSRLPLV------------
ASWKTYPLFFGTAVFSFESIGVV-L-----PLENKMKDARRFPTVLSLGMSIIT--SLYI
TVGTLGYLRFGDDIKASITLNLPSCWL--YQSVKLLYLVGILCTYSLQFYVPAEIIIPVI
VSWVSPRWALALDLSIRLTM--VCL----TCILAILIPRLDLVLSLVGSVSSSALALIIP
PLLEITTYYSEGLS-PLTVAKDALISILGFAGFVVGTYQALHELSQPEHSLTFPNST---
IFIQRV---------------------

--------------------------------------------------MSVTKSTEGP
QGAVAIKLDLMSPPESAK---KLENKDST-FLDE--S-PSESP-----------------
GSKKTKG

PF01490 // ENSGT00390000011245_0_Domain_1 (128, 700)

ITGFQALVHLVKGNMGTGILGLPLAVKNAGILMGPLSLLVMGFIACHCMHI--
LVKCAQ--RF-------CKR----------------------------------------
-----------------LNKPFMDYG--DTVMHGLEANPSAWLRNH--AHWGRHIVSFFL
IV---------------------------------------------------------T
QLGFCCVYIVFLADNLKQVVEAVNSTTNNCHSNET-V-ILTPTMDSRLYMLSFLPFLVLL
VLIRNLRILTIFSMLANISMLVSLVIITQYITQEI----PDPSRLPLV------------
ASWKTYPLFFGTAIFSFESIGVV------LPLENKMKDARHFPAILSLGMSIIT--ALYI
GIGALGYLRFGDDIKASITLNLPNCWL--YQSVKLLYVAGILCTYALQFYVPAEIIIPFS
ISRVSTRWALPLDLSIRIAM--VCL----TCLLAILIPRLDLVLALVGSVSSSALALIIP
PLLEVTTFYSEGMS-PLTIFKDALISILGFVGFVVGTYQALDELLKSGDSLPFSNST---
TFIQ-----------------------

------------------------------------------------------------
-----------------MSTRRLCSEDYNDYSSTDVT-PEGSPPAG-I-NGFTRPESYQR
FGES-

PF01490 // ENSGT00390000011245_0_Domain_1 (126, 702)

NGTTWYQTLIHLLKGNIGTGLLGLPLALKNAGILLGPLSLLVMGVVAVHCMSI--
LVKCAH--HF-------CYR----------------------------------------
-----------------FQKQFLDYG--GTVMYGLESTPVACLRTH--AIWGRRVVGLFL
IL---------------------------------------------------------T
QLGFCCVYFVFLADNLRQVVSSANSTTTDCQSNRT-V-TLTPTMDSRLYMLSLLPFVVLL
SFIQNLKILSIFSMLANVAMLISLVVIYQYIVRDI----PDPSTLPLA------------
AAWKTYPLFFGTAIFAFEGIGVV-L-----PLENKMKNPRQFPLILYVGMTIVT--ILYI
SLGVLGYLRFGAAIQASITLNLPNCWL--YQAVKLLFSFGIFFTYAVQFYVPAEIIIPPL
VARVPERWGWLVNLLLRVVL--VGI----TCVLAILIPRLDIVISLVGSVSSSALALIFP
PLLEIATYYTEGMH-PLLIAKDVLISLFGFVGFVVGTYEALVELATP----AA-VINGTS
TSGQ-----------------------

------------------------------------------------------------
-----------------MSTQRLRNEDYHDYSSTDVS-PEESPSEG-L-NNLSSPGSYQR
FGQS-N

PF01490 // ENSGT00390000011245_0_Domain_1 (127, 699)

STTWFQTLIHLLKGNIGTGLLGLPLAVKNAGIVMGPISLLIIGIVAVHCMGI--
LVKCAH--HF-------CRR----------------------------------------
-----------------LNKSFVDYG--DTVMYGLESSPCSWLRNH--AHWGRRVVDFFL
IV---------------------------------------------------------T
QLGFCCVYFVFLADNFKQVIEAANGTTNNCHNNET-V-ILTPTMDSRLYMLSFLPFLVLL
VFIRNLRALSIFSLLANITMLVSLVMIYQFIVQRI----PDPSHLPLV------------
APWKTYPLFFGTAIFSFEGIGMV-L-----PLENKMKDPRKFPLILYLGMVIVT--ILYI
SLGCLGYLQFGANIQGSITLNLPNCWL--YQSVKLLYSIGIFFTYALQFYVPAEIIIPFF
VSRAPEHCELVVDLFVRTVL--VCL----TCILAILIPRLDLVISLVGSVSSSALALIIP
PLLEVTTFYSEGMS-PLTIFKDALISILGFVGFVVGTYEALYELIQPSNAPIFINS--TR
AFI------------------------

--------------------------------------------------MPVTKSAGSP
QVATTVKLDLVSSPESTK---KVQSQDPS-VVNG--N-SSES------------------
-SKTTKG

PF01490 // ENSGT00390000011245_0_Domain_1 (128, 700)

ITGFQTLVHLVKGNMGTGILGLPLAVKNAGILMGPLSLLVMGLIACHCMHI--
LVRCAQ--RF-------CHR----------------------------------------
-----------------LNKPFMDYG--DTVMHGLEASPNVWLQNH--AHWGRYIVSFFL
IV---------------------------------------------------------T
QLGFCCVYIVFLADNLKQVVEAVNGTTFSCHNNET-V-VPMPTMDSRLYMLTFLPVLGLL
VFIRNLRVLTIFSLLANISMLVSLIIIAQYIIQGI----PDPSQLPMV------------
ASWKTYPLFFGTAIFSFESIGVV-L-----PLENKMKDAHRFPTILSLGMSIIT--TLYI
AIGALGYLRFGDDIKASITLNLPNCWL--YQSVKLLYVVGILCTYALQFYVPAEIIIPFA
VSQVSKRWALPLDLSIRIAM--VCL----TCMLAILIPRLDLVLSLVGSVSSSALALIIP
PLLEMTTYYSEGMS-PLTIIKDALISILGFVGFVVGTYQALDELIESGNTLPLSNST---
MFFQ-----------------------

-----------------------------------------------------MS-----
-------LLGRD-----Y-NSELNS-----LDNRSQS-PSESSS-S-ITS-----E-NVH
PA-GEAG

PF01490 // ENSGT00390000011245_0_Domain_1 (128, 700)

LSMMQTLIHLLKCNIGTGLLGLPLAIKNAGLLVGPVSLLAIGVLTVHCMVI--
LLNCAQ--HL-------SQR----------------------------------------
-----------------LQKTFVNYG--EATMYSLETCPNTWLRTH--AVWGRWSSAVSH
-RLECSGKI---------SAHC---NPHLQGS-SDS--PAQAS-VAEIYRYTVSFLLIIT
QLGFCSVYFMFMADNLQQMVEEAHVTSNICQPRE--ILALTPILDIRFYMLTILPFLILL
VFIQNLKVLSIFSTLANITTVGSMALIFEYIMQGI----PYPSNLPLM------------
ANWKTFLLFFGTAIFTFEGVGMV-L-----PLKNQMKHPQQFSFVLYLGMSIVI--ILYI
FLGTLGYMKFGSDTQASITLNLPNCWL--YQSVKLMYSIGIFFTYALQFHVPAEIIIPFA
VSQVSESWALFVDLSVRSGL--VCL----TCVSAILIPRLDLVISLVGSVSSSALALIIP
ALLEIVIFYSEDMS-CVTLAKDIMISILGLLGCIFGTYQALYELTQPINHSM-ANSTGVY
A--------------------------

------------------------------------------------------------
-----------------MSTQRLRNEDYQDYSSTDAS-PEESPSEG-L-GSFS-PGAYQR
FGES-N

PF01490 // ENSGT00390000011245_0_Domain_1 (127, 699)

STTWFQTLIHVLKGNIGTGLLGLPLAVKNAGILLGPLSLLVIGVVAVHCMGI--
LVKCAH--HF-------CRR----------------------------------------
-----------------LNKPFVDYG--DTVMYGLEASPSSWLRNH--AHWGRRTVDFFL
IV---------------------------------------------------------T
QLGFCCVYFVFLADNFKQVIEAANGTTNNCHNNET-V-ILTPTMDSRLYMLAFLPVLVLL
VFIRDLRVLSVFSLLANISMLVSLVMIYQFIVQRI----PDPSRLPLV------------
ASWRTYPLFFGTAIFAFEGIGMV-L-----PLENKMKDPQKFPLILYLGMAIVT--VLYI
SLGSLGYLQFGASIQGSITLNLPNCWL--YQSVKLLYSIGIFFTYGLQFYVPAEIIVPFF
VSRVPEQCRLLVDLSVRTAM--VCL----TCVLAILVPRLDLVISLVGSVSSSALALIIP
PLLEIATYSSEGLR-LVTIAKDALISLLGFVGFVVGTYEALAELIQPSATPVSTNS--TG
AF-------------------------

--------------------------------------------------MSVTKSTEGP
QGAVAIKLDLMSPPESAK---KLENKDST-FLDE--S-PSESA-----------------
GLKKTK

PF01490 // ENSGT00390000011245_0_Domain_1 (127, 700)

GITVFQTLIHLVKGNMGTGILGLPLAVKNAGILMGPLSLLVMGFIACHCMHI--
LVKCAQ--RF-------CKR----------------------------------------
-----------------LNKPFMDYG--DTVMHGLEANPNAWLQNH--AHWGRHIVSFFL
IV---------------------------------------------------------T
QLGFCCVYIVFLADNLKQVVEAVNSTTNNCYPNET-V-ILTPTMDSRLYMLSFLPFLVLL
VLIRNLRILTIFSMLANISMLVSLVIIIQYITQEI----PDPSRLPLV------------
ASWKTYPLFFGTAIFSFESIGVV------LPLENKMKNARHFPAILSLGMSIVT--SLYI
GMAALGYLRFGDDIKASISLNLPNCWL--YQSVKLLYIAGILCTYALQFYVPAEIIIPFA
ISRVSTRWALPLDLSIRLVM--VCL----TCLLAILIPRLDLVISLVGSVSGTALALIIP
PLLEVTTFYSEGMS-PLTIFKDALISILGFVGFVVGTYQALDELLKSEDSHPFSNST---
TFVR-----------------------

------------------------------------------------------------
-----------------MSTQRLRNEDYHDYSSTDVS-PEESPSEG-L-NNLSSPGSYQR
FGQS-N

PF01490 // ENSGT00390000011245_0_Domain_1 (127, 699)

STTWFQTLIHLLKGNIGTGLLGLPLAVKNAGIMMGPISLLVIGIVAVHCMGI--
LVKCAH--HF-------CRR----------------------------------------
-----------------LNKSFVDYG--DTVMYGLESSPCSWLRNH--AHWGRHVVDFFL
IV---------------------------------------------------------T
QLGFCCVYFVFLADNFKQVIEAANGTTNNCHNNET-V-ILNPTMDSRLYMLSFLPFLVLL
VFIRNLRALSIFSLLANITMLVSLIMIYQFIVQRI----PDPSHLPLV------------
APWKTYPLFFGTAIFAFEGIGMV-L-----PLENKMKDPRKFPLILYLGMVIVT--ILYI
SLGCLGYLQFGANIQGSITLNLPNCWL--YQSVKLLYSIGIFFTYALQFYVPAEIIIPFF
VSRAPEHCELVVDLFVRTVL--VCL----TCILAILIPRLDLVISLVGSVSSSALALIIP
PLLEVTTFYSEGMS-PLTIFKDALISVLGFVGFVVGTYEALYELIQPSNAPIFINS--TR
AFI------------------------

--------------------------------------------------MSVTKSTEGP
QGAVAIKLDLMSPPESAK---KLENKDST-FLDE--S-PSESA-----------------
GLKKTK

PF01490 // ENSGT00390000011245_0_Domain_1 (127, 700)

GITVFQALIHLVKGNMGTGILGLPLAVKNAGILMGPLSLLVMGFIACHCMHI--
LVKCAQ--RF-------CKR----------------------------------------
-----------------LNKPFMDYG--DTVMHGLEANPNAWLQNH--AHWGRHIVSFFL
IV---------------------------------------------------------T
QLGFCCVYIVFLADNLKQVVEAVNSTTNNCHSNET-V-ILTPTMDSRLYMLSFLPFLVLL
VLIRNLRILTIFSMLANISMLVSLVIIIQYITQEI----PDPSRLPLV------------
ASWKTYPLFFGTAIFSFESIGVV-RF--CLWYKSKMKNARHFPAILSLGMSIVT--SLYI
GMAALGYLRFGDDIKASISLNLPNCWL--YQSVKLLYIAGILCTYALQFYVPAEIIIPFA
ISRVSTRWALPLDLSIRLIM--VCL----TCLLAILIPRLDLVISLVGSVSGTALALIIP
PLLEVTTFYSEGMS-PLTIFKDALISILGFVGFVVGTYQALDELLKSGDSHPFSNST---
TFVR-----------------------

------------------------------------------------------------
------------------------------------------------------------
---------

PF01490 // ENSGT00390000011245_0_Domain_1 (130, 630)

WFQTLIHLLKGNIGTGLLGLPLAVKNAGILIGPLSLLVMGLVAVHCMGI--
LVKCAH--HF-------CHR----------------------------------------
-----------------LNKPFVDYG--DTVMYGLEASPSSWLRNH--AHWGRHIVDFFL
IV---------------------------------------------------------T
QLGFCCVYFVFLADNFKQXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXX-XXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXEI----PDPTHLPLV------------
ASWKTYPLFFGTAIFAFEGIGMV-L-----PLENKMKDPRKFSLILYVGMAIVM--ALYI
SLGSLGYLQFGANIQGSITLNLPNCWL--YQSVKLLYSIGIFFTYALQFYVPAEIIVPFF
VARVPEHCELLIDLSVRTML--VCL----T------------------------------
------------------------------------------------------------
---------------------------

------------------------------------------------------------
-----------------MSTQRLRNEDYHDYSSTDVS-PEESPSEG-L-NNLSSPGSYQR
FGQS-N

PF01490 // ENSGT00390000011245_0_Domain_1 (127, 699)

STTWFQTLIHLLKGNIGTGLLGLPLAVKNAGIVMGPISLLIIGIVAVHCMGI--
LVKCAH--HF-------CRR----------------------------------------
-----------------LNKSFVDYG--DTVMYGLESSPCSWLRNH--AHWGRRVVDFFL
IV---------------------------------------------------------T
QLGFCCVYFVFLADNFKQVIEAANGTTNNCHNNET-V-ILTPTMDSRLYMLSFLPFLVLL
VFIRNLRALSVFSLLANITMLVSLVMIYQFIVQRI----PDPSHLPLV------------
APWKTYPLFFGTAIFSFEGIGMV-L-----PLENKMKDPRKFPLILYLGMVIVT--ILYI
SLGCLGYLQFGANIQGSITLNLPNCWL--YQSVKLLYSIGIFFTYALQFYVPAEIIIPFF
VSRAPEHCELVVDLFVRTVL--VCL----TCILAILIPRLDLVISLVGSVSSSALALIIP
PLLEVTTFYSEGMS-PLTIFKDALISILGFVGFVVGTYEALYELIQPSNAPIFINS--TR
AFI------------------------

-----------------------------------------------------MS-----
-------LLGRD-----Y-NSELNS-----LDNRSQS-PSESSS-S-ITS-----E-NVH
PA-GEAG

PF01490 // ENSGT00390000011245_0_Domain_1 (128, 700)

LSMMQTLIHLLKCNIGTGLLGLPLAIKNAGLLVGPVSLLAIGVLTVHCMVI--
LLNCAQ--HL-------SQR----------------------------------------
-----------------LQKTFVNYG--EATMYSLETCPNTWLRTH--AVWGKWSSAVSH
-RLECSGKI---------SAHC---NPHLQGS-SDS--PA------QIYRYIVSFLLIIT
QLGFCSVYFMFMADNLQQMVEEAHVTSNICQPRE--ILALTPILDIRFYMLTILPFLILL
VFIQNLKVLSVFSTLANITTVGSMALIFEYIMQGI----PYPSNLPLM------------
ANWKTFLLFFGTAIFTFEGVGMV-L-----PLKNQMKHPQQFSFVLYLGMSIVI--ILYI
FLGTLGYMKFGSDTQASITLNLPNCWL--YQSVKLMYSIGIFFTYALQFHVPAEIIIPFA
VSQVSESWALFVDLSVRSGL--VCL----TCVSAILIPRLDLVISLVGSVSSSALALIIP
ALLEIVIFYSEDMS-CVTLAKDIMISILGLLGCIFGTYQALYELTQPINHSM-ANSTGVY
A--------------------------

------------------------------------------------------------
-----------------MSTQRLRNEDYQDYSSTDAS-PEESPSES-L-GNFS-PGTYQR
FGES-N-TTQA------------------------------

PF01490 // ENSGT00390000011245_0_Domain_1 (162, 699)

LMLLLVIGIVAVHCMGL--
LVKC-AR-HF-------CHR----------------------------------------
-----------------LNKPFVDYG--DTVMYGLESCPSPWLRNH--AHWGRRIVDFFL
IV---------------------------------------------------------T
QLGFCCVYFVFLADNFKQVIEAANGTTNNCHINET-V-ILTPTMDSRLYMVTFLPFLVLL
VFIRNLRVLSIFSLLANLSMLVSLVMIYQFIVQGI----PNPSNLPLV------------
APWKTYPLFFGTAIFAFEGIGVV-L-----PLENKMKDPQKFPLILYLGMAIVT--ALYI
SLGSLGYLQFGASIQGSITLNLPNCWL--YQSVKLLYSIGIFFTYGLQFYVPAEIIVPFF
VSRSPENCRLLVELVVRTLM--VCL----TCILAVLIPRLDLVISLVGSVSSSALALIIP
PILEVTTYASEGLS-PLTLAKDVLISLLGFVGFVVGTYEALSELIQPSAAPVSSNS--TG
A--------------------------

--------------------------------------------------MSVTKSTEGP
QGAIAIKLDLMSPPESAK---KLENKDST-FLDE--S-PSESP-----------------
GSKKTKG

PF01490 // ENSGT00390000011245_0_Domain_1 (128, 700)

ITGFQTLVHLVKGNMGTGILGLPLAVKNAGILMGPLSLLVMGFVACHCMHI--
LVKCAR--RF-------CKR----------------------------------------
-----------------LNKPFMDYG--DTVMHGLEANPSAWLQNH--AHWGRHIVSFFL
IV---------------------------------------------------------T
QLGFCCVYIVFLADNLKQVVEAVNSTTSNCHSNET-V-ILTPTMDSRLYMLSFLPFLVLL
VLIRNLRILTIFSMLANISMLVSLVIITQYIAQEI----PDPSRLPLV------------
ASWKTYPLFFGTAIFSFESIGVV------LPLENKMKDARHFPTMLSLGISIIT--VLYT
SVGTLGYLRFGDDIKASISLNLPNCWL--YQSVKLLYIAGILCTYALQFYVPAEIIIPFA
ISRVSTRWALPLDLSIRIAM--ACL----TCLLAILIPRLDLVLALVGSVSSSALALIIP
PLLEVTTFYSEGMS-PLTIFKDALISILGFVGFVVGTYQALDELLKSGDSLPVSNST---
TFIQ-----------------------

--------------------------------------------------MSMAKSARDP
QEAVDLNLDLRSPPESAK---KLPNTDSS-FLDG--S-PSESP-----------------
SMETTK

PF01490 // ENSGT00390000011245_0_Domain_1 (127, 700)

GITAFQTLVHLVKGNIGTGVLGLPLAMRNAGILMGPLGLLAMGLISCHCMHI--
LIRCAR--RF-------CHR----------------------------------------
-----------------FNKPFMDYG--DTVMHGLEANPSAWLRNH--AHWGRYIVSFFL
IV---------------------------------------------------------T
QMGFCCVYIVFLADNLKQVVEAVNSTTNNCHYE-T-V-ILTPTMDSRLYMLTFLPFLVLI
VLIRNLRVLTVFSLLANITMLISLIIIVQYIVQEI----PDPRRLPLV------------
ANWKTYSLFFGTAIFSFESIGVV-L-----PLENKMKDARRFPVILSLGMSIIT--ALYV
SVGTLGYLRFGDDVKASITLNLPNCWL--YQSVKILYIIGILCTYALQFYVPAEIIVPLA
TSHVSKRWALPLDLFIRLAM--VSL----TCILAILIPRLDLVLSLVGSLSGSALALIIP
PLLEITTYYSEGLS-PVTIVKDTLISILGFVGFVMGTYQALDELIQSGDSLTFSNST---
VFIQ-----------------------

------------------------------------------------------------
-----------------MSTQRLRNEDYRDYSSTDVS-PEESPSEG-L-NSFSSPGSYQR
FGES-

PF01490 // ENSGT00390000011245_0_Domain_1 (126, 702)

NSTTWFQTLIHLLKGNIGTGLLGLPLAVKNAGILMGPLSL-VIGLVAVHCMGI--
LVKCAH--HF-------CRR----------------------------------------
-----------------LNKPFVDYG--DTVMYGLEATPISWLRNN--AHWGRHTVDFFL
IV---------------------------------------------------------T
QLGFCCVYFVFLADNFKQVIEAANGTTTNCHNNET-V-ILTPTMDSRLYMLAFLPFLVLL
VFVRNLRVLSIFSLLANITMVVSLVMIYQFIVQDI----PDPKFLPLV------------
ASWQTYPLFFGTAIFAFEGIGMV-L-----PLENKMKDPRKFSLILYVGMAIIT--VLYI
SLGCLGYLQFGANIQGSITLNLPNCWL--YQSVKLLYSIGIFFTYALQFYVPAEIIIPFF
VARAPEHCELVIDLSVRTML--VCL----TCVLAILVPRLDLVISLVGSVSSSALALIIP
PLLEIATYYSEGMS-PITIVKDALISLLGFVGFVVGTCVTLYELIQPSSAPIFVNS--TS
AFV------------------------

------------------------------------------------------------
------------------------------------------------------------
---------

PF01490 // ENSGT00390000011245_0_Domain_1 (130, 699)

WYQTLIHLLKGNIGTGLLGLPLALKNAGILLGPLSLLVMGIVAVHCMSI--
LVKCAH--HF-------CYR----------------------------------------
-----------------FQKQFVDYG--GAVMYGLESTPSAWLRTH--AVWARRVVGLFL
IL---------------------------------------------------------T
QLGFCCVYFVFLADNLRQVVSAANDTTTDCNSNRT-V-ALTPTMDSRLYMLSLLPFVVLL
SFIQNLKVLSIFSMLANVAMLVSLVVIYQYIVRDI----PDPSNLPLV------------
AAWKTYPLFFGTAIFAFEGIGVV-L-----PLENKMKNPRQFPVILYVGMTIVT--ILYI
SLSVLGYLRFGASIQASITLNLPNCWL--YQAVKLLFSFGIFFTYAVQFYVPAEIIIPPL
VARVSERWGWVVNLLLRVAL--VSV----TCVLAILIPRLDIVISLVGSVSSSALALIFP
PLLEIATYYVEGMH-PLLIAKDVAISLIGFVGFVVGTCRPKCRASRLFVHPPWLVSRTCA
YF-------------------------

------------------------------------------------------------
-----------------MSTQRLRNEDYHDYSSTDVS-PEESPSEG-L-NNLSSPGSYQR
FGQS-N

PF01490 // ENSGT00390000011245_0_Domain_1 (127, 699)

STTWFQTLIHLLKGNIGTGLLGLPLAVKNAGIVMGPISLLVIGIVAVHCMGI--
LVKCAH--HF-------CRR----------------------------------------
-----------------LNKSFVDYG--DTVMYGLESSPCSWLRNH--AHWGRHVVDFFL
IV---------------------------------------------------------T
QLGFCCVYFVFLADNFKQVIEAANGTTNNCHNNET-V-ILTPTMDSRLYMLSFLPFLVLL
VFIRNLRALSVFSLLANITMLVSLIMIYQFIVQRI----PDPSHLPLV------------
APWKTYPLFFGTAIFAFEGIGMV-L-----PLENKMKDPRKFPLILYLGMVIVT--ILYI
SLGCLGYLQFGANIQGSITLNLPNCWL--YQSVKLLYSIGIFFTYALQFYVPAEIIIPFF
VSRAPEHCELVVDLFVRTVL--VCL----TCILAILIPRLDLVISLVGSVSSSALALIIP
PLLEVTTFYSEGMS-PLTIFKDALISVLGFVGFVVGTYEALYELIQPSNAPIFINS--TR
AFI------------------------

-----------------------------------------------------MS-----
-------LLGKD-----Y-NSELNS-----LDNRSQS-PSESSS-S-ITS-----E-NVH
PA-GEAG

PF01490 // ENSGT00390000011245_0_Domain_1 (128, 700)

LSMMQTLIHLLKCNIGTGLLGLPLAIKNAGLLVGPVSLLAIGVLTVHCMVI--
LLNCAQ--HL-------SQR----------------------------------------
-----------------LQKTFVNYG--EATMYSLETCPNTWLRTH--AVWGKWSSAVSH
-RLECSGKI---------SAHC---NPHFQGS-SDS--PAQAS-VAEIYRYTVSFLLIIT
QLGFCSVYFMFMADNLQQMVEEAHVTSNICQPRE--ILALTPILDIRFYMLTILPFLILL
VFIQNLKVLSVFSTLANITTVGSMALIFEYIMQGI----PYPSNLPLM------------
ANWKTFLLFFGTAIFTFEGVGMV-L-----PLKNQMKHPQQFSFVLYLGMSIVI--ILYI
FLGTLGYMKFGSDTQASITLNLPNCWL--YQSVKLMYSIGIFFTYALQFHVPAEIIIPFA
VSQVSESWALFVDLSVRSGL--VCL----TCVSAILIPRLDLVISLVGSVSSSALALIIP
ALLEIVIFYSEDMS-CVTLAKDIMISILGLLGCIFGTYQALYELTQPINHSM-ANSTGVY
A--------------------------

--------------------------------------------------MPTAKSARGP
QGAADLKLDLKPPPRSAN---KQQNKDSD-FLDG--S-PSESP-----------------
GSETTK

PF01490 // ENSGT00390000011245_0_Domain_1 (127, 700)

GITAFQTLVHLVKGNIGTGILGLPLAMKNAGILLGPLSLLAMGFISCHCMHI--
LVRCAQ--RF-------CHR----------------------------------------
-----------------LNKPFLDYG--DTVMHGLEATPSAWLQNH--AHWGRRIVSFFL
IV---------------------------------------------------------T
QMGFCCVYIVFLADNLKQVVEAVNSTTNNCRYNET-V-TLTPTMDSRLYMLTFLPFLALL
VLIRNLRVLTVFSLLANVSMLVSLIIITQYIIQGI----PDPGQLPLA------------
ANWKTYSLFFGTAVFSFESIGVV-L-----PLENKMKDARRFPLILSLGMSIIT--ALYV
SIGTLGYLRFGNDIKASITLNLPNCWL--YQSVKILYVIGILCTYALQFYVPAEIIIPFA
ISQVSKRWALPLDLSIRLAM--VCL----TCVLAILVPRLDLVLSLVGSVSSSALALIIP
PLLEIATYYSEGMS-PLTIIKDALISILGFLGFVMGTYQALDELIQSRDSLTFSNST---
LFIQ-----------------------

--------------------------------------------------MSVTKSARCP
QVATPLNLD---LPESAK---KLQSQDPS-PANG--S-SSES------------------
-TKKTKG

PF01490 // ENSGT00390000011245_0_Domain_1 (128, 700)

ITGFQTLVHLVKGNMGTGILGLPLAVKNAGILMGPLSLLVMGLIACHCMHI--
LVRCAQ--RF-------CHR----------------------------------------
-----------------LNKPFMDYG--DTVMHGLASSPNAWLQNH--AHWGRCVVSFFL
IV---------------------------------------------------------T
QLGFCCVYIVFLADNLKQVVEVVNSTTISCHKNET-V-VLTPTMDSRLYMLSFLPVLGLL
VFVRNLRVLTIFSLLANISMLVSLVIIAQYIIQEI----PDASQLPLV------------
ASWKTYPLFFGTAIFSFESIGVV-L-----PLENKMKDARGFPTILSLGMSIIT--TLYI
AIGALGYLRFGDDIKASITLNLPNCWL--YQSVKLLYVVGILCTYALQFYVPAEIIIPLA
VSQVSKRWALPVDLSIRLAL--VCL----TCMLAILIPRLDLVLSLVGSVSSSALALIIP
PLLEVVTYYGEGIS-PLTVTKDALISILGFMGFVVGTYQALDELIKSGNSPALSNST---
MFIQ-----------------------

------------------------------------------------------------
------------------------------------------------------------
---------P

PF01490 // ENSGT00390000011245_0_Domain_1 (131, 700)

TQALIHLLKCSIGTGLLGLPLAVKNAGLLVGPVSLLAIGILTVHCMVI--
LLNCAH--HL-------TQR----------------------------------------
-----------------LQKTFMNYG--ETTMYSLENCSSSWLRTH--SVWGRY------
---------------------------------------------------TVSSLLIIT
QLGFCSVYFMFMADNLQQIVEEAHIISNTCQPRK--ILVLTPILDIRVYMLTILPFLIML
AFIQNLKVLSIFSTLANITTLGSMALIFEYIVQ-I----PYPINLPLM------------
ANWKTFLLFFGTTIFTFEGVGMV-L-----PLKNQMKNPQKFSFVLYLGMSLVI--FLYI
CLGTLGYMKFGPDTQASITLNLPNCWL--YQSVKVMYSIGIFFTYALQFHVPAEIIIPFA
ISQVSESWALPVDLSVRTAL--VCL----TCVSAILIPRLDLVISLVGSVSSSALALIIP
PLLEIITFYPEDMS-CVTIAKDIMISMLGLLGCILGTYQALYEFTQPVNRSM-ANSTVIY
A--------------------------

-----------------------------------------------------MS-----
-------LLGRD-----Y-NSELNS-----LDNRSQS-PLESSN-S-ITS-----E-NVH
PA-GEAG

PF01490 // ENSGT00390000011245_0_Domain_1 (128, 263)

LSTMQTLIHLLKCSIGTGLLGLPLAMKNAGLLVGPVSLLAIGVLTVHCMVI--
LLNCAQ--HL-------SQR----------------------------------------
-----------------LQKTFVNYE--EATMYSLETCPNTWLRTH--AVWG--------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------GI----PYPSNLPLM------------
ANWKTFLLFFGTAIFTFEGVGMV-L-----PLKNQMKHPQQFSFVLYLGMSIVI--ILYI
FLGTLGYMKFGSDTQASITLNLPNCWL--YQSVKLMYSIGIFFTYALQFHVPAEIIIPFA
ISQVSESWALFVDLSVRSAL--VCL----TCVSAILIPRLDLVISLLGSVSSSALALIIP
ALLEIVIFYSEDMS-CVTLAKDIMISILGLLGCIFGTYQALYELTQPINHSM-ANSTGVY
A--------------------------

---------------------------------------------------MA------P
EG-----LNSAPIPPATMSTQRLRNEDYNDYSSTEVS-PTETPSNG-L-DNFSNSSSYQR
FGEV-NG

PF01490 // ENSGT00390000011245_0_Domain_1 (128, 701)

TTRLQTLIHLLKGNIGTGLLGLPLAVKNAGILLGPLSLIVMGIVATHCMGI--
LVKCAH--HF-------CRR----------------------------------------
-----------------LHKPFLDYG--DTVMYGLEASPSSWLRTH--SLWGRRIVSFFL
VV---------------------------------------------------------T
QLGFCSVYFVFMADNFKQVVEAANGTTNNCHNNET-V-LPIPTMDSRLYMLTFLPFVVLL
VFIRNLKALTLISVLANITMLASLIMIYQHIVQGI----PDPRNLPLA------------
ANWKTYPLFFGTAIFAFEGIGVV-L-----PLENKMKDPRHFPGILYLGMTIIT--LLYI
TLGSLGYLQYGAAIQGSITLNLPNCWL--YQSVKLLYSIGIFFTYSLQFYVPAEIINPFF
VSRVTERWALVVDLSVRIVM--ASL----TCALAILIPRLDLVISLVGSVSSSALALIIP
PLLDITTYYSEGMS-PIIITKDILISLFGFVGFVVGTYQAIYELIQPNVSPTFSNV--TS
AFVQ-----------------------

------------------------------------------------------------
------------------------------------------------------------
----------MQILIHLLKSNIGTGFLGLPLAVKNAGLLGRGTLSSKLGVGG----YL--
YLECAYTLSF-------PPR----------------------------------------
-----------------LQKTFMNYE--EATMYSLGTCPNPWLKSH--SAWGRY------
---------------------------------------------------TMSFL-LIT
LLGFCSTSFMFTVDNSQQIVEP-QSTSNTCQPRK--ALVLTHVLDTLFYMLMILPFLVPL
GN---------------------LHL-------------P--------------------
-------------------FLQV

PF01490 // ENSGT00390000011245_0_Domain_1 (504, 660)

-L-----PLKNQTENPQQFPIILYLGMPFII--FLYI
CLGTLGYIKFGSNTQANITLNLPNCWP--YQSVKLMYSIGIFFTYALQFQVPAEIILPFI
ISHMSEDWTLFADLTTPTSL--VCL----TCVRASILNQD---------TISLALALIIP
PLLEI-TTYSEGMS-CVTIVKDI-ISILGLLGCVLGTYQALYEMTQLAHFSV-ANDIGVY
T--------------------------

------------------------------------------------------------
------------------------------LSSSGSY-PLRSSSS-------IDSE-KVQ
PAAEA

PF01490 // ENSGT00390000011245_0_Domain_1 (126, 702)

AGLSTTQTLIHMLKCNIGTGLLGLPLAIKNAGLLVGPISLLAIGILTVHCMVI--
LLNCAH--HL-------TQK----------------------------------------
-----------------LHKTFVSYS--EAMMYSLETCSNPWLRAH--SMWGXXXXXXXX
XXXXXXXXX---------XXXX-------XXXXXXXXXXXXXXXXXXXXXYMVSFLLIIT
QLGFCSVYFMFMADNFQQIVEEAHITSRTCQPRK--NLVLHSILDIRFYMLIILPFLILL
VLVQNLKVLSIFSTLASI-TLGSMALIFEHILQGI----PFPSDLPLM------------
ANWETFLLFFGTALFTFEGVGMV-L-----PLKNQMKNPQHFSFVLYIGMSLVV--VLYI
LLGTLGYMKFGSDTQASITLNLPNCWL--YQSVKLMYSVGIFFTYALQFHVPAEIIIPFA
ISQVSENWTLCVDLSVRTGL--VCL----TCVPAILIPRLDLVISLVGSVSSSALALIIP
PILEITTFYSEDLS-GATIAKDIMISFLGLLGCIFGTYQALYDLIQPVSF-I-ANSTDVY
A--------------------------

------------------------------------------------------------
-----------------MSTERLRNEDYQDYSSTDAS-PEESPSEG-L-GNFS-PGAYQR
FGES-N

PF01490 // ENSGT00390000011245_0_Domain_1 (127, 699)

NTTWFQTLIHLLKGNIGTGLLGLPLAVKNAGILLGPLSLLVIGVVAVHCMGI--
LVKCAH--HF-------CHR----------------------------------------
-----------------LNKPFVDYG--DTVMYGLEASPSPWLRNH--AHWGRRTVDFFL
IV---------------------------------------------------------T
QLGFCCVYFVFLADNFKQVVEAANRTTNNCHNNET-V-ILTPTMDSRLYMLAFLPFLVLL
VFIRNLRVLSIFSLLANMSMLVSLVMIYQFIVQRI----PNPSHLPLV------------
ASWRTYPLFFGTAIFAFEGIGMV-L-----PLENKMKDPQKFPLILYLGMAIVT--VLYI
SLGSLGYLQFGASIQGSITLNLPNCWL--YQSVKLLYSIGIFFTYGLQFYVPAEIIMPFF
VSRAPEQCRLLVDLSVRTAM--VCL----TCMLAILIPRLDLVISLVGSVSSSALALVIP
PLLEIATYSSEGLR-PLTIAKDALISVLGFAGFMVGTYEALAELAQPSAAPNSTNS--TG
AFAY-----------------------

---------------------------------------MAD-P-REPENGAVE------
LG-----TPNAAAPTGTMSTRRLRSEDYNDYSSTDVT-PEGSPPDG-M-NGFAHPESYQR
FGET-N

PF01490 // ENSGT00390000011245_0_Domain_1 (127, 699)

GTTWYQTLIHLLKGNIGTGLLGLPLAVKNAGILLGPLSLLVMGVVAVHCMGI--
LVKCAH--HF-------CNR----------------------------------------
-----------------FQKQFVDYG--GAVMYGLEATPSACLRTH--AIWGRRVVGLFL
II---------------------------------------------------------T
QLGFCCVYFVFLADNLKQVVSAANGTTNDCSSNRT-V-VMTPTMDSRLYMLSILPFVVLL
TFIQNLKVLSIFSMLANVAMLVSLVVIYQYIVRDI----PDPRNLPLA------------
AAWKTYPLFFGTAIFAFEGIGVV-L-----PLENKMKKPRQFPVILYVGMTIVT--ILYI
SLSVLGYLRFGADIQASITLNLPNCWL--YQAVKLLFSFGIFFTYAVQFYVPAEIIIPPL
VARVSERWGWLVNLLLRMAL--VCV----TCVLAILIPRLDLVISLVGSVSSSALALIFP
PLLEIATYYSEGMH-PLVIAKDIAISLFGFVGFVVGTYEALVELV----APAATVVNATT
VLVQ-----------------------

-----------------------------------------------------TS-----
-------LLGKD-----F-SSGPSS-----LDNRSKS-PSESRGR-------IALE-NIH
PAEEA

PF01490 // ENSGT00390000011245_0_Domain_1 (126, 702)

NGLSIMQTLIHLLKCNIGTGLLGLPLAMKNAGLLVGPISLLAIGILTVHCMVI--
LLNCAH--HL-------SQR----------------------------------------
-----------------LQKTFVSYG--EAMMCSLETCPNAWLRTH--SVWGRLHF--AF
SCILITSVD---------EELCPCCRHHMTMPQ-DTDYQTGE--VMGQFRYTVSFLLITT
QLGFCSVYFMFMADNLQQMVEEAHMTSNNCQPRK--ILLLTPILDIRFYMLTILPFLVLL
VFIQNLRMLSIFSMLANVTTLGSMALIFEYIIQEI----PDPSSLPLM------------
ASWKTFLLFFGTAIFTFEGVGMV-L-----PLKNQMKHPQQFSFVLYLGMSIVI--ILYI
CLGTLGYMKFGSNTQASITLNLPNCWL--YQSVKLMYSIGIFFTYALQFQVPAEIIIPFV
ISQVSESWTLFIDLSVRTAL--VCL----TCVSAILIPRLDLVLSLVGSVSSSALALIIP
PLLELITFYAEDMS-CVTIAKDIMISILGLLGCVFGTYQALYELIQPINHSI-TNS----
---------TGVYA-------------

------------------------------------------------------------
-----------------MSTQRLRNEDYRDYSSTDVS-PEESPSDT-L-NNFSSPGSYQR
FGES-S

PF01490 // ENSGT00390000011245_0_Domain_1 (127, 692)

STTWFQTLIHLLKGNIGTGLLGLPLAIKNAGILMGPLSLLLMGLVAVHCMGL--
LVKCAH--HF-------CHR----------------------------------------
-----------------LNKPFLDYG--DTVMYGLEASPSAWLRNH--AHWGRHIVDFFL
IV---------------------------------------------------------T
QLGFCSVYFVFLADNFKQVIEAANGTTNNCHNNET-V-ILTPTMDSRLYMASFLPFLVLL
VFIRNLRVLSVFSLLANVTMLVSLVMIYQFIVQEI----PDPSHLPLV------------
ASWKTYPLFFGTAIFAFEGIGMV-L-----PLENKMKDPQKFSLILYVGMAIVS--ALYI
SLGTLGYLQFGAAIQGSITLNLPNCWL--YQSVKLLYSIGIFFTYALQFYVPAEIIIPFF
VSRVPEPWRLVIDLSVRTVL--VCL----TCVVAILVPRLDPVLSLVGSVSSSALALIIP
PLLEIATYYSEGLS-PLAIIKDALISMLGFLGFV--------------------------
---------------------------

-----------------------------------------------------MS-----
-------CSSKA-----RGSQALPS-----LGEQ--------TANR-DHGTGGSPS-SAP
GPRGGARAQP

PF01490 // ENSGT00390000011245_0_Domain_1 (131, 701)

AQTLIHLLKCNVGTGLLGLPLAVKNAGLLVGPVSLLAIGILTVHCMVI--
LLNCAQ--HL-------TQR----------------------------------------
-----------------LQKTFVNYG--ETTMYSLECCASPWLRTH--SAWGRY------
---------------------------------------------------AVSFLLIVT
QLGFCSVYFMFMADNLQQIVEEAHVLSNTCQPRR--ALELTPLLGIHSYMLTILPFLIML
VFIRNLKLLSIFSVLANVTTLGSTALIFEYI--GI----PYPSNLPLM------------
ANWKTFLLFFGTTIFTFEGVGMV-L-----PLKNQMKNPQKFSIVLYLGMSLVI--ALYI
CMGTLGYMKFGSDTQASITLNLPNCWL--YLSVKVMYSVGIFFTYALQFHVPAEIIVPLA
VSQVSESWALLVDLAVRTAL--VCL----TCVSAILVPRLDLVISLVGSVSSSALALVIP
PLLEIVTFYPEDMS-YVTVAKDIVISTLGLLGCILGTYQAIYEWAQPISHAV-ANSTGVY
V--------------------------

--------------------------------------------------MSVTKSARSP
QVATPLNLD---LPESAK---KLQSQDPS-PANG--S-SSES------------------
-SKKTKG

PF01490 // ENSGT00390000011245_0_Domain_1 (128, 700)

ITGFQTLVHLVKGNMGTGILGLPLAVKNAGILMGPLSLLVMGLIACHCMHI--
LVRCAQ--RF-------CHR----------------------------------------
-----------------LNKPFMDYG--DTVMHGLAFSPNAWLQNH--AHWGRRVVSFFL
IV---------------------------------------------------------T
QLGFCCVYIVFLADNLKQVVEAVNSTTISCHKNET-V-VLTPTMDSRLYMLSFLPVLGLL
VFVRNLRVLTIFSLLANISMLVSLVIIAQYIIQEI----PDASQLPLV------------
ASWKTYPLFFGTAIFSFESIGVV-L-----PLENKMKDARGFPTILSLGMSIIT--TLYI
AIGALGYLRFGDDIKASITLNLPNCWL--YQSVKLLYVVGILCTYALQFYVPAEIIIPLA
VSQVSKRWALPVDLSIRLAL--VCL----TCMLAILIPRLDLVLSLVGSVSSSALALIIP
PLLEVVTYYGEGIS-PLTVTKDALISILGFMGFVVGTYQALDELIKSGNSPALSNST---
MFIQ-----------------------

------------------------------------------------------------
------------------------------------------------------------
----------M

PF01490 // ENSGT00390000011245_0_Domain_1 (132, 700)

QTLIHLLKCNIGTGLLGLPLAIKNAGLLVGPISLLAIGILTVHCMVI--
LLNCAH--HL-------SQR----------------------------------------
-----------------LQKTFVDYG--EAMMYSLETCPNTWLRTH--SMWGR-------
--------------------------------------------------YTVSFLLIIT
QLGFCSVYFMFMADNLQQMVEEAHVTSNTCQPRK--SLVLIPILDIRFYMLIILPFLVLL
VFIQNLKVLSIFSTLANITTLGSMALIFEYILQGI----PDPSKLPLM------------
ASWKTFLLFFGTAVFTFEGVGMV-L-----SLKNQMKQPQRFSFVLYLGMSLVI--VLYI
CLGTLGYMKFGPNTQASITLNLPNCWL--YQSVKLMYSVGIFFTYTLQFHVPAEIIIPVV
ISQVSENWALSVDLSVRTVL--VCL----TCISAILIPRLDLVISLVGSVSSSALALIIP
PILELITFYPEDMS-CVTIAKDIMISILGLLGCVFGTYQALYELTQPISYFI-ANSTYA-
---------------------------

--------------------------------------------------MPVTKSAEGS
GEATTLTLDLMTSPKSTK---KLQIKASS-FLDG--S-ASDSS-----------------
VLEKTR

PF01490 // ENSGT00390000011245_0_Domain_1 (127, 386)

GITAFQTLVHLVKGNMGTGVLGLPLAVKNAGILVGPLSLLVMGFVACHCMHI--
LVRCAQ--RF-------CHR----------------------------------------
-----------------------------------------------------HVVSVFL
VV---------------------------------------------------------T
QLGFCCVYIVFLADNLKQVAEAVNGTTSSCHEGT--V-APTPAVDSRLYMLA--------
---------------------------------DI----PDPSRLPLA------------
ASWKTYPLFFGTAIFSFESIGVV-L-----PLENRMKDARYFPAILSLGMSIIT--ALYI
AIGALGYLRFGDDVRASITLNLPNCWL--YQSVKLLYVIGILCTYALQFYVPAEIVVPFA
VSRVSERWALPVDLSVRLAM--VCL----TCVLAILVPRLDLVLSLVGSVSSSALALVIP
PLLEIATYSSEGLR-PVTIAKDALISLLGFVGFVTGTYQALSELTESEASLPSTNST---
IFNQE----------------------

-----------------------------------------------------MS-----
-------LLGRN-----Y-NKELNS-----LDHGTQS-PSESSR-S-TTS-----E-NVH
PA-GEAG

PF01490 // ENSGT00390000011245_0_Domain_1 (128, 700)

LSMMQTLIHLLKCNIGTGLLGLPLAIKNAGLLVGPVSLLAIGVLTVHCMVI--
LLNCAH--HL-------SQR----------------------------------------
-----------------LHKTFMNYG--EATMYSLETCPNTWLRTH--AVWGRVSLLLPR
LE-LCSGMI---------SAHC---NPHIQGS-SDS--PAPASRVARIYRYTVSFLLIIT
QLGFCSVYFMFMADNLQQMVEEAHVTSNICQPRE--ILVLTPILDIRVYMLTILPFLILL
VFIQNLKVLSIFSTLANITTLGSMALIFEYIMQGI----PYPSHLPLM------------
ANWKTLLLFFGTAIFTFEGVGMV-L-----PLKNQMKHPQQFSFVLYLGMSIVI--ILYI
CLGTLGYMKFGSDTQASITLNLPNCWL--YQSVKLMYSIGIFFTYALQFHVPAEIIIPFA
ISQVSESWALFVDLSVRSAL--VCL----SCVSAILIPHLDLVVSLVGSVSSSALALIIP
PLLEIIILYSEDMS-YVTIAKDIMISILGLLGCIFGTYQALYELTQPIDHSM-ANSTGVY
A--------------------------

-----------------------------------------------------MS-----
-------LLGRN-----Y-SKELNS-----LDHGSQS-PSESGS-S-TAS-----E-NVH
PA-GEAGLSMMQTLIHLLKCNIGTGLLGLPLAIKNAGLLVGPVSLLAIGILTVHCMVI--
LLNCAH--HL-------SQR----------------------------------------
-----------------LHKTFVNYG--EATMYSLETCPNTWLRTH--AVWGRVSLLLPS
--TMCSGMI---------SAHC---NPHIQGS-SNS--PAQASQVARIYRCPPP-----H
R

PF01490 // ENSGT00390000011245_0_Domain_1 (362, 700)

LGFCSVYFMFMADNLQQMVEEAHVTSNICQPRK--ILVLTPILDIRVYMLTILPFLILL
VFIQNLKVLSIFSTLANITTLGSMALIFEYIMQGI----PYPSDLPLM------------
ANWNTFLLFFGTAIFTFEGVGMV-L-----PLKNQMKHPQQFSFVLYLGMSIVI--ILYI
CLGTLGYMKFGSDTQASITLNLPNCWL--YQSVKLMYSIGIFFTYALQFHVPAEIIIPFA
ISQVSESWALFVDLSVRSAL--VCL----TCVSAILIPRLDLVISLIGSVSSSALALIIP
PLLEIVILYSEDMS-YVTIAKDIMISILGLLGCIFGTYQALYELTQPINHSM-ANSTGVY
A--------------------------

------------------------------------------------------------
-----------------MSTQRLRNEDYHDYSSTDVS-PEESPSEG-L-SRLSSPGSYQR
FGQS-N

PF01490 // ENSGT00390000011245_0_Domain_1 (127, 455)

STTWFQTLIHLLKGNIGTGLLGLPLAVKNAGIVMGPVSLLVIGIIAVHCMGI--
LVKCAH--HF-------CRR----------------------------------------
-----------------LNKSFVDYG--ETVTYGLESSPCSWLQNH--AHWGRHVVDFFL
IV---------------------------------------------------------T
QLGFCCVYFVFLAENFK-------------------------------------------
--------------------------------QRI----PDPSNLPLV------------
APWKTYPLFFGTAIFAFEGIGMV-L-----PLENKMKDPQKFPLILYLGMAIVT--ILYI
SLGCLGYLRFGANIQGSVTLNLPNCWL--YQSVKLLYSIGIFFTYALQFYVPAEIIIPVF
VSRAPEHCELAVDLFVRTVL--VCL----TCILAILIPRLDLVISLVGSVSSSALALIIP
PLLEVTTFYSEGMS-PLTIFKDALISILGFVGFVVGTYEALYELIQPSNAPIFINS--TH
AFI------------------------

--------------------------------------------------MSMAKSARSP
QEAVDLDLDLRSPPESAK---KLPNKDSS-FLDG--S-PSESP-----------------
SLETTK

PF01490 // ENSGT00390000011245_0_Domain_1 (127, 700)

GITAFQTLVHLVKGNMGTGVLGLPLAMKNAGILMGPLSLLAIGFISCHSMHI--
LIRCAR--RF-------CHR----------------------------------------
-----------------FNKPFMDYG--DTVMHGLEANPSAWLRNH--AHWGRRIVSFFL
IV---------------------------------------------------------T
QMGFCCVYIVFLADNLKQVVEAVNSTTNNCYYK-T-E-ILTPTMDSRLYMLTFLPFLVLI
VLIRNLRVLTVFSLLANITMLTSLIIIVQYIVQEI----PDPRQLPLV------------
ANWKTYSLFFGTAIFSFESIGVV-L-----PLENKMKDARRFPVILSLGMSIVT--ALYV
SVGSLGYLRFGDDVKASITLNLPNCWL--YQSVKILYIVGILCTYALQFYVPAEIIIPLA
TSRVSKRWALPLDLFIRLAM--VSL----TCILAILIPRLDLVLSLVGSLSGSALAFIIP
PLLEISTYYSEGLS-PITIVKDTLISILGFVGFVMGTYQALDELIQSGDSPTFSNST---
IFIQ-----------------------

------------------------------------------------------------
-----------------MSTQRLRNEDYHDYSSTDGS-PEESPSDG-L-SNPTSPGSYQR
FGES-N

PF01490 // ENSGT00390000011245_0_Domain_1 (127, 698)

STTWFQTLIHLLKGNIGTGLLGLPLAVKNAGILMGPLSLLVIGIVAVHCMAI--
LVKCAH--HF-------CHR----------------------------------------
-----------------LNKSFVDYG--DTVMYGLESSPCSWLRNH--AHWGRHIVDFFL
IV---------------------------------------------------------T
QLGFCCVYFVFLADNFKQVIEAANGTTNNCHSNET-V-ILTPTMDSRLYMLSFLPFLVLL
VFVRSLRALSIFSLLANVSMLVSLVMLYQFIVQRI----PDPSRLPLV------------
APWKTYPLFFGTAIFAFEGIGMV-L-----PLENKMKEPQKFPLILYVGMAIVT--ILYI
SLGCLGYLQFGANIQGSITLNLPNCWL--YQSVKLLYSIGIFFTYALQFYVPAEIIIPFF
VSRVPQRCGLVVDLFVRTVL--VCL----TCVLAILIPRLDLVISLVGSVSSSALALIIP
PLLEVTTYYSEGIS-PLTITKDALISILGFVGFVVGTYEALNELIQPTNAPILINS--TR
AFI------------------------

------------------------------------------QYLVLIKHAGKCL-----
-------LFQKN-----RISTFLNY-----NVSSGRS-PSRCPS---------------R
CFLSSSLH

PF01490 // ENSGT00390000011245_0_Domain_1 (129, 666)

SPAQTLIHLLKCSIGTRLLGLPLAVKKPGLL--PLSLLAIGIPAVHCTVI--
LLNCATSQPI--------------------------------------------------
----------------------------LFTLFSLLRCPHPLGHRT--VEP---------
------------------------------------------------NRRPISFLLIIT
QLGFC--------NNLQQIVEEAHVISGTCQPRK--ILVLTPILDIRFYMPTVLPFLITL
AFTQNLKLLSIFSTLANIATLGFLQL---YEFLGI----PYPSNLPLM------------
AYWKTFLLFFGTTIFTFEGVGV--------------KNPQQFSLVLYLGLSFVI--SLCI
CLGTLGYMKFGSDTQASITLDLHNCCL--YQSVKVMYSIGIFFTYSLQFHVPADIITLFA
ISPVSESWALLAGLSVRTAM--VCL----SCVSTVLIPHLEPFLSLVGSVSSSALGLVIP
PLLEILCGHL----------KGRRDQHLGLLGCILGTYQTLCEFTQPTGCSV-ANSKVVY
V--------------------------

------------------------------------------------------------
-----------------MSTQRLRNEDYHDYSSTDVS-PEESPSEG-L-NNLSSPGSYQR
FGQS-N

PF01490 // ENSGT00390000011245_0_Domain_1 (127, 699)

STTWFQTLIHLLKGNIGTGLLGLPLAVKNAGIVMGPISLLIIGIVAVHCMGI--
LVKCAH--HF-------CRR----------------------------------------
-----------------LNKSFVDYG--DTVMYGLESSPCSWLRNH--AHWGRRVVDFFL
IV---------------------------------------------------------T
QLGFCCVYFVFLADNFKQVIEAANGTTSNCHNNET-V-ILTPTMDSRLYMLSFLPFLVLL
VFIRNLRALSIFSLLANITMLVSLVMIYQFIVQRI----PDPSHLPLV------------
APWKTYPLFFGTAIFSFEGIGMV-L-----PLENKMKDPRKFPLILYLGMVIVT--ILYI
SLGCLGYLQFGANIQGSITLNLPNCWL--YQSVKLLYSIGIFFTYALQFYVPAEIIIPFF
VSRAPEHCELVVDLFVRTVL--VCL----TCILAILIPRLDLVISLVGSVSSSALALIIP
PLLEVTTFYSEGMS-PLTIFKDALISILGFVGFVVGTYEALYELIQPSNAPIFINS--TR
AFI------------------------

------------------------------------------------------------
-----------------MSTQRLRNEDYHDYSSTDVS-PEESPSEG-L-NNLSSPGSYQR
FGQS-N

PF01490 // ENSGT00390000011245_0_Domain_1 (127, 699)

STTWFQTLIHLLKGNIGTGLLGLPLAVKNAGIVMGPISLLVIGIVAVHCMGI--
LVKCAH--HF-------CRR----------------------------------------
-----------------LNKSFVDYG--DTVMYGLESSPCSWLRNH--AHWGRHVVDFFL
IV---------------------------------------------------------T
QLGFCCVYFVFLADNFKQVIEAANGTTNNCHNNET-V-ILTPTMDSRLYMLSFLPFLVLL
VFIRNLRALSVFSLLANITMLVSLIMIYQFIVQRI----PDPSHLPLV------------
APWKTYPLFFGTAIFAFEGIGMV-L-----PLENKMKDPRKFPLILYLGMVIVT--ILYI
SLGCLGYLQFGANIQGSITLNLPNCWL--YQSVKLLYSIGIFFTYALQFYVPAEIIIPFF
VSRAPEHCELVVDLFVRTVL--VCL----TCILAILIPRLDLVISLVGSVSSSALALIIP
PLLEVTTFYSEGMS-PLTIFKDALISVLGFVGFVVGTYEALYELIQPSNAPIFINS--TR
AFI------------------------

--------------------------------------------------MSMTKSAGGP
QGAVDLKLDLKPSSESAK---KLQNKDSS-FLDG--S-PSESP-----------------
DLETT

PF01490 // ENSGT00390000011245_0_Domain_1 (126, 702)

KGITAFQALVHLVKGNIGTGVLGLPLAMKNAGXXVGPLSLLAMGFISCHCMHI--
LVRCAQ--RF-------CHR----------------------------------------
-----------------LNKPFMDYG--DTVMHGLEASPSTWLRNH--AHWGRRIVSFFL
IV---------------------------------------------------------T
QMGFCCVYIVFLADNLKQVVEAVNSTTNNCHYNRT-V-ILTPTMDSRLYMLAFLPFLVLL
VFVRNLRALSIFSLLANITMLVSLIIITQSIIQGI----PDPSRLPLV------------
ANWKTYSLFFGTAVFSFESIGVV-L-----PLENKMKDARRFPVILSLGMSIVT--ALYI
SIGTLGYLRFGNDIKASITLNLPNCWL--YQSVKILYIIGILCTYALQFYVPAEIIIPFA
TSQVLKRWALPLELFIRLAM--VSL----TCILAILIPRLDLVLSLVGSLSSSALALIIP
PLLEITTYYSEGMS-PITIIKDALISILGFVGFVMGTYQALEELIQSEDPLTFSNST---
IFIQ-----------------------

--------------------------------------------------MSVTK---ST
EGAVAVKLDLMSPPESAK---KLENKDST-FLDE--S-PSESP-----------------
GLKKTK

PF01490 // ENSGT00390000011245_0_Domain_1 (127, 700)

GITVIQALIHLVKGNMGTGILGLSLAVKNAGILMGPLSLLVMGLIACHCMHI--
LVRCAQ--RF-------CKR----------------------------------------
-----------------LNKPFMDYG--DTVMHGLEASPSAWLQNH--AHWGRHIVSFFL
IV---------------------------------------------------------T
QLGFCCVYIVFLADNLKQVVEAVNSTTNNCHSNET-V-ILTPTMDSRLYMLSFLPLLVLL
VFIRNLRILTIFSMLANISMLVSLVIITQYITQEI----PDPSRLPLV------------
ASWKTYPLFFGTAIFSFESIGVV-L-----PLENKMKNARHFPAILSLGMSIVT--SLYI
SIATLGYLRFGDDIKASISLNLPNCWL--YQSVKLLYIAGILCTYALQFYVPAEIIIPFA
ISQVSTRWALPLDLSIRLAM--VCL----TCLLAVLIPRLDLVISLVGSVSSSALALIIP
PLLEVTTFYSEGMS-PLTIFKDALISILGFVGFVVGTYQALDELLKSGDSPPFSNST---
TFLR-----------------------

--------------------------------------------------MPEAS-----
-------LLGKG-----G-NRD-QN-----LHCGSKA-PLESSSSSS-----SSSS-GDP
RDGEAVSL

PF01490 // ENSGT00390000011245_0_Domain_1 (129, 700)

SLMKILVHLLKTNIGTGLLGLPLAVKNAGLLVGPVSLVAIGVLTVHCMDM--
VLNCAH--HL-------AQR----------------------------------------
-----------------LQKTCVNYE--EAAMYSLEACPNSWLRTH--SVWGRY------
---------------------------------------------------TVSALLVTT
QLGFCSAYFMFMAENLQQIVEEASITSNTCQPRK--AVVLTPRLDVRLYMLMILPFLALL
VLVHNPRALAIFSTLASITTLGSLALIFEYLIQ-L----PHTSSLPLA------------
GSWKTFLLFLGTAIFTFEGVGMV-L-----PLKNQTKNPQQFSCVLYGGMSLVI--VLYV
CLGTLGYMKFGSDTQASITLNLPSCWW--HQSVKLLYSIGIFFTYALQFQVPAEIIVPLA
VSHVSESWALLVDLTVRTAL--VCL----TCFSAILIPRLDLVLSLVGSVSSSALALIIP
PLLEVATFSSEDVS-RVTIAKDVMISILGFLGCIFGTYQALYELSQPVNPPM-GNSTGVY
A--------------------------

----------------------------------------------------ISL-----
-------LARDN-----N-SEP-KS-----LDDGAKS-LSESRSS-------ITSE-SVR
PEEEA

PF01490 // ENSGT00390000011245_0_Domain_1 (126, 702)

NGLSIMQTLIHLLKCNIGTGLLGLPLAVKNAGLLVGPFSLLAIGILTVHCMVI--
LLNCAH--CL-------SQR----------------------------------------
-----------------LQKTFVNYG--EAMMYSLETCPSAWLRTH--SVWGR-------
--------------------------------------------------YTVSFLLIIT
QLGFCSVYFMFMADNLQQMVEEAYVTSNTCQPRK--ILVLTPTLDIRFYMLAILPFLILL
VFIQNLRVLSVFSTLASITTLWSMALIFEYIVQEI----PDPRNLPLM------------
ASWKTFLLFFGTAIFTFEGVGMV-L-----SLKNQMKHPQQFSFVLYFGMSLVI--VLYI
CLGTLGYMKFGSNTQASITRNLPNCWL--YQSVKLMYSIGIFFTYALQFHVPTEIIIPVV
ISQASESWVLFADLSVRTAL--VCL----TCVSAILIPRLDLVISLVGSVSSSALALIIP
PLLELITFYPEDMS-CVTIAKDIMISILGLLGCVFGTYQALCELIQPINYSI-ANSTAVY
A--------------------------

------------------------------------------------------------
-----------------MSTQRLRNEDYHDYSSTDVS-PEESPSEG-L-NNLSSPGSYQR
FGQS-N

PF01490 // ENSGT00390000011245_0_Domain_1 (127, 699)

STTWFQTLIHLLKGNIGTGLLGLPLAVKNAGIVMGPISLLVIGIVAVHCMGI--
LVKCAH--HF-------CRR----------------------------------------
-----------------LNKSFVDYG--DTVMYGLESSPCSWLRNH--AHWGRHVVDFFL
IV---------------------------------------------------------T
QLGFCCVYFVFLADNFKQVIEAANGTTNNCHNNET-V-ILTPTMDSRLYMLSFLPFLVLL
VFIRNLRALSVFSLLANITMLVSLIMIYQFIVQRI----PDPSHLPLV------------
APWKTYPLFFGTAIFAFEGIGMV-L-----PLENKMKDPRKFPLILYLGMVIVT--ILYI
SLGCLGYLQFGANIQGSITLNLPNCWL--YQSVKLLYSIGIFFTYALQFYVPAEIIIPFF
VSRAPEHCELVVDLFVRTVL--VCL----TCLLAVLIPRLDLVISLVGSVSSSALALIIP
PLLEVSTFYSEGMS-PLTIFKDALISVLGFVGFVVGTYEALYELIQPSNAPIFINS--TR
AFI------------------------

--------------------------------------------------MPVTKSADSP
QVATTVKLDLVSSPESTK---KVQSQDPS-VVNG--N-SSES------------------
-SKTTKG

PF01490 // ENSGT00390000011245_0_Domain_1 (128, 700)

ITGFQTLVHLVKGNMGTGILGLPLAVKNAGILMGPLSLLVMGLIACHCMHI--
LVRCAQ--RF-------CHR----------------------------------------
-----------------LNKPFMDYG--DTVMHGLEASPNVWLQNH--AHWGRYIVSFFL
IV---------------------------------------------------------T
QLGFCCVYIVFLADNLKQVVEAVNGTTFSCHNNET-V-VPMPTMDSRLYMLTFLPVLGLL
VFIRNLRVLTIFSLLANISMLVSLIIIAQYIIQGI----PDPSQLPMV------------
ASWKTYPLFFGTAIFSFESIGVV-L-----PLENKMKDAHRFPTILSLGMSIIT--TLYI
AIGALGYLRFGDDIKASITLNLPNCWL--YQSVKLLYVVGILCTYALQFYVPAEIIIPFA
VSQVSKRWALPLDLSIRIAM--VCL----TCMLAILIPRLDLVLSLVGSVSSSALALIIP
PLLEMTTYYSEGMS-PLTIIKDALISILGFVGFVVGTYQALDELIESGNTLPLNS-T---
MFFQ-----------------------

------------------------------------------------------------
-----------------MSTQRLRDEDYRDYSSTDAS-PEESPSEG-L-NNFSSSGSYMR
FGES-N

PF01490 // ENSGT00390000011245_0_Domain_1 (127, 698)

STTWFQTLIHLLKSNIGTGLLGLPLAVKNAGILMGPLSLLVIGLVAVHCMSI--
LVKCAH--HF-------CYR----------------------------------------
-----------------LNKPFVDYG--DTVMYGLEASPVSWLRNH--AHWGRHIVDFFL
IV---------------------------------------------------------T
QLGFCCIYFVFLADNFKQVIEMANGTTSNCHNNET-V-ILTPTMDSRLYMLTFLPFMVLL
VFVRNLRALSIFSLLANITMAVSLVMIYQFTVQNI----PDPSHLPLV------------
ASWKTYPLFFGTAIFAFEGIGMV-L-----PLENKMKDPKKFSLILYVGMTIVT--ALYI
SLGILGYLQFGANIQGSITLNLPNCWL--YQSVKLLYSVGIFFTYALQFYVPAEIIIPFF
VARGPEHCELVIDLSVRTVL--VCL----TCILAILIPRLDLVISLVGSVSSSALALIIP
PLLEITTYYSEGMS-PITIVKDALISILGFMGFVVGTCLTLYELVQPTSAPIFINS--TS
AFV------------------------

--------------------------------------------------MLKKS-----
-------LLGKD-----Y-NNELN------LDNGSKS-PSKSSSSS-SNSSSSTPE-NAP
PAEEDNAL

PF01490 // ENSGT00390000011245_0_Domain_1 (129, 701)

SLLQTLVHLLKCNVGTGLLGLPLAIKNAGLLVGPISLLAIGILTVHCMVI--
LLNCAH--HL-------SQR----------------------------------------
-----------------LQTTFVNYG--EATMYSLETCPSPWLRSH--SVWGRY------
---------------------------------------------------TVSFLLIIT
QLGFCSVYFMFMADNLQQIVEEVHVTSNTCQPRK--FLVLTPILDIRIYMLTILPFLIML
VFIRNLKVLSVFSTMANITTLGSMILIFEYIIQ-I----PDPSNLPLM------------
ANWKTFLLFFGTAIFTFEGVGMV-L-----PLKNQMKNPQHFPLVLYVGMSLVI--FLYS
CLGILGYMKFGSDTQASITLNLPNCWL--YQSVKLMYSVGIFFTYALQFHVPAEIIIPFA
VSQVPENWALFVDLSVRTAL--VCL----TCVSAILIPRLDLVISLVGSVCSSALALIIP
PLLEIITFYSEDIS-CATIAKDIMISILGFLGCIFGTYQAFYELTQPINHSM-ANSTGVY
IS-------------------------

------------------------------------------------------------
-----------------MSTRRLRSEDYNDYSSTEAT-PEGSPPEG-A-NGFASPASYQR
FGES-YG

PF01490 // ENSGT00390000011245_0_Domain_1 (128, 699)

TTWFQTLIHLVKGNIGTGLLGLPLAVKNAGIVLGPLSLLVMGIAAVHCMSL--
LVKCAH--HF-------CHK----------------------------------------
-----------------YQRPFVDYG--DAVMYGLEATPSTWLRSH--AIWGRYVVGFFL
IL---------------------------------------------------------T
QLGFCCVYFVFLADNLKQVISAANSTTNDCYSNKT-I-ELAPAMDSRLFILSLLPFLVLL
VYIQNLKFLSIFSMVANLVMLCSLVMINWYIFTGI----PDPSHLPLV------------
AGWKTYPLFFGTAIFAFEGIGVV-L-----PLENKMKNPRQFPTILYVGMALVT--VLYI
SLGVLGYLRFGADIQASITLNLPNCWL--YQSVKLLYSIGIFFTFALQFYVPAEIILPVA
ISQVPERWALWLNLLLRTCL--VCV----TCLLAILIPRLDIVISLVGSVSSSALALIIP
PLLEIATYSSEGIH-PVTVAKDLLISILGFAGFVVGTYESLWALATSPVSNATHASGP--
---------------------------

------------------------------------------------------------
---------SWH-----W--GILQE-----WGRCIHS-FFGACG--------------VS
SLLSVSPPRP

PF01490 // ENSGT00390000011245_0_Domain_1 (131, 700)

TQTLIHLLKCSLGAGLLGLPLAIKNAGLLVGLVSLLAMGILTVHCMVI--
LLNCTQ--RL-------TRR----------------------------------------
-----------------LQKTFVNYG--ETTMYSLESCSSPWLRTH--SEWGRWILR---
----------------------------------------------------FGLLINHY
QLGFCSVYFMFIADSLQQVMEEAHITSNTCQPRE--IPMLTPILDMRFYMLTILPFLIIL
AFIQNLRLLSIFSMLANITTLGSMALIFEYIIQGI----PYPSNLPLM------------
ANWKTLLLFFGTTIFTFESIGMV-L-----PLKNQMKNPQKFSFVLYLGMSLVT--ALYI
CLGTPGYMRFGSDTQASITLNLPNCWL--YQSAKVMYSVGIFFTYALQLHVPAEITIPFA
ISQASESWALLVDLSVRTAL--VCL----TCVFPILVPRLDLVLSLVGSVSSSALALIIP
PLLEIITFYPEDMS-CVTIAKDIVISTLGLLGCFLGVYQALYELTQPTSHST-ANFTGVY
V--------------------------

-----------------------------------------------------MS-----
-------LLGRD-----Y-NSELNS-----LDNGPQS-PSESSS-S-ITS-----E-NVH
PA-GEAG

PF01490 // ENSGT00390000011245_0_Domain_1 (128, 700)

LSMMQTLIHLLKCNIGTGLLGLPLAIKNAGLLVGPVSLLAIGVLTVHCMVI--
LLNCAQ--HL-------SQR----------------------------------------
-----------------LQKTFVNYG--EATMYGLETCPNTWLRAH--AVWGRWNLALSP
-RLECSGKI---------SAHC---NPHLQGS-SNS--PAQASRVAGIYRYTVSFLLVIT
QLGFCSVYFMFMADNLQQMVEKAHVTSNICQPRE--ILTLTPILDIRFYMLIILPFLILL
VFIQNLKVLSVFSTLANITTLGSMALIFEYIMEGI----PYPSNLPLM------------
ANWKTFLLFFGTAIFTFEGVGMV-L-----PLKNQMKHPQQFSFVLYLGMSIVI--ILYI
LLGTLGYMKFGSDTQASITLNLPNCWL--YQSVKLMYSIGIFFTYALQFHVPAEIIIPFA
ISQVSESWALFVDLSVRSAL--VCL----TCVSAILIPRLDLVISLVGSVSSSALALIIP
ALLEIVIFYSEDMS-CVTIAKDIMISIVGLLGCIFGTYQALYELPQPISHSM-ANSTGVH
A--------------------------

------------------------------------------------------------
-----------------MSTQRLRNEDYHDYSSTDVS-PEDSPSEG-L-SNFA-PGSYQR
FGDN-N

PF01490 // ENSGT00390000011245_0_Domain_1 (127, 699)

NTTWFQTLIHLLKGNIGTGLLGLPLAVKNAGLLMGPLSLLVIGIVAVHCMGI--
LVKCAH--HF-------CRR----------------------------------------
-----------------LNKPFVDYG--DTVMHGLESSSSGWLRSH--AHWGRLVVDFFL
IV---------------------------------------------------------T
QLGFCSVYFVFLADNFKQVIEAANGTTNNCHNNET-V-VLMPTMDSRLYMLAFLPFLVLL
VFIRNLRVLSIFSLLANISMLVSLVMIYQLVIQRI----PDPRHLPLV------------
APWKTYPLFFGTAIFAFEGIGMV-L-----PLENRMKNPRQFPVILYVGMAIVT--AVYI
SLGCLGYLQFGASVQGSITLNLPNCWL--YQSVKLLYSIGIFFTYALQFYVPAEIIIPFF
VSRAPEHCELLVDLCVRTAM--VCL----TCVLATLIPRLDLVISLVGSVSSSALALIIP
PLLEIITFYSEGMS-PLTILKDALISILGFMGFVVGTYEALAELIQPRSSHITTHS--PS
AFI------------------------

------------------------------------------------------------
-----------------MSTQRLRNEDYHDYSSTDVS-PEESPSEG-L-GSFS-PGSYQR
LGEN-SS

PF01490 // ENSGT00390000011245_0_Domain_1 (128, 699)

MTWFQTLIHLLKGNIGTGLLGLPLAVKNAGLLLGPLSLLVIGIVAVHCMGI--
LVKCAH--HL-------CRR----------------------------------------
-----------------LNKPFLDYG--DTVMYGLECSPSTWIRNH--SHWGRRIVDFFL
VV---------------------------------------------------------T
QLGFCCVYFVFLADNFKQVIEAANGTTTNCNNNET-V-ILTPTMDSRLYMLTFLPFLVLL
SFIRNLRILSIFSLLANISMFVSLIMIYQFIVQRI----PDPSHLPLV------------
APWKTYPLFFGTAIFAFEGIGVV-L-----PLENKMKDSQKFPLILYLGMAIIT--VLYI
SLGSLGYLQFGADIKGSITLNLPNCWL--YQSVKLLYSIGIFFTYALQFYVAAEIIIPAI
VSRVPERFELVVDLSARTAM--VCV----TCVLAVLIPRLDLVISLVGSVSSSALALIIP
PLLEVTTYYGEGIS-PLTITKDALISILGFVGFVVGTYESLWELIQPSHSDSSTNS--TS
AFI------------------------

----------------------------------------------------KLD-----
-------LMSPP-----E-----NAK---KLQNKDAI-FLD-----------RSPS-DSL
CSEKN

PF01490 // ENSGT00390000011245_0_Domain_1 (126, 702)

ESITWFQALVHLVKGNMGTGILGLPLAMKNAGLLLGPLSLLAMGAIACHCMHI--
LVRCAQ--RF-------CCR----------------------------------------
-----------------LNKPFMDYG--VTVLHGLEASPXXXXXXX--XXXXXXXXXXXX
XXXXXXXXXXXX--------XX-------XX---XX----X---------XXXXXXXXXX
XXXXXXXX---XXXXXXXXXXXXXXXXXXXXXXX--X-XXXXXXXXXXXX-X-------X
XXXXXXX------------XX--XXXXXXXXXXXX----XXXXXXXXX------------
XXXXXXXXXXXXXXXXXXXXXXV-L-----PLENKMKDARRFPAALYLGMSIIT--ALYV
SIGVLGYLQFGDDIKASITLNLPNCXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXX--XXX----XXVLAILIPCLDLVISLVGSVSSGALALIIP
PLLEILTFYPEGLS-PLTIVKDALISILGFVGFVVGTYQALHELMQSRHSLTFPNSTIFV
Q--------------------------

--------------------------------------------------MSVTKSTEGP
QGAVAIKLDLMSPPESAK---KLENKDST-FLEE--S-PSESA-----------------
GLKKTK

PF01490 // ENSGT00390000011245_0_Domain_1 (127, 597)

GITVFQALIHLVKGNMGTGILGLPLAVKNAGILMGPLSLLVMGFIACHCMHI--
LVKCAQ--RF-------CKR----------------------------------------
-----------------LNKPFMDYG--DTVMHGLEANPNAWLQNH--AHWGRHIVSFFL
IV---------------------------------------------------------T
QLGFCCVYIVFLADNLKQVVEAVNSTTNNCYSNET-V-ILTPTMDSRLYMLSFLPFLVLL
VLIRNLRILTIFSMLANISMLVSLVIIIQYITQEI----PDPSRLPLV------------
ASWKTYPLFFGTAIFSFESIGVV------LPLENKMKNARHFPAILSLGMSIVT--SLYI
GMAALGYLRFGDDIKASISLNLPNCWL--YQSVKLLYIAGILCTYALQFYVPAEIIIPFA
ISRVSTRWALPLDLSIRLVM--VCL----T------------------------------
------------------------------------------------------------
---------------------------

--------------------------------------------------MPVTKSTEGP
QGAGTLKLDIVPSSPSAK---QLQDKDSN-FVDG--S-SSESP-----------------
GLEKT

PF01490 // ENSGT00390000011245_0_Domain_1 (126, 702)

KGITGFQTLVHLVKGNMGTGILGLPLAVKNAGILMGPLSLLVMGFIACHCMHI--
LVRCAQ--HF-------CRR----------------------------------------
-----------------LNKPFMDYG--DTVMHGLEASPSAWLRDH--SHWGXXXXXXXX
XX---------------------------------------------------------X
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-X-XXXXXXXXXXXXXXXXXX----
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXEIPDPSRLPLV------------
ASWRTYPLFFGTAIFSFESIGVV-L-----PLENKMKDARHFPAILSLGMCIIT--ALYI
GIAALGYLRFGDDIKASITLNLPNCWL--YQSVKLLYIIGILCTYALQFYVPAEIVIPFA
TSQVPKRWALPLDLSLRLAM--VLL----TGILAILIPRLDLVLSLVGSVSSSALALIIP
PLLEITTYYSEGLS-PLTIAKDAFISFVGFVGFVAGTYQALDELIVSGESVTFSNST---
TVFQ-----------------------

------------------------------------------------------------
-----------------MSTQRLRNEDYHDYSSTDVS-PEESPSEG-L-SNF-SPGSYQR
FGES-NSTTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--
XX

PF01490 // ENSGT00390000011245_0_Domain_1 (183, 702)

XXXX--XX-------XXX----------------------------------------
-----------------LNKPFVDYG--DTVMYGLESSPTSWLRNH--AHWGRHIVDFFL
IV---------------------------------------------------------T
QLGFCCVYFVFLADNFKQVIEAANGTTNNCHNNET-V-ILTPTMDSRLYMLTFLPFLVLL
VFVRNLRALSVFSMLANITMLVSLVMIYQFIVQRI----PNPSHLPLV------------
APWKTYPLFFGTAIFAFEGIGMV-L-----PLENKMKDPRKFPLILYVGMTIIT--ILYI
SLGCLGYLQFGVNIQGSITLNLPNCXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXX--XXX----XXVLAILIPRLDLVISLVGSVSSSALALIIP
PLLEILTFYPEGLS-PLTIVKDALISILGFVGFVVGTYEALCELIQPSRAPVSNNS--TS
AFI------------------------

-----------------------------------------------------MS-----
-------LLGRD-----Y-SSGLNS-----LNDGSKS-LSENSS-S-TTS-----E-NVH
PA-EEAG

PF01490 // ENSGT00390000011245_0_Domain_1 (128, 700)

LSLLQTLIHLLKCNIGTGLLGLPLAIKNAGLLVGPISMLAIGILTVHCMVI--
LLNCAH--HL-------SQR----------------------------------------
-----------------LQKTFVNYG--EATMYSLESCPNTWLRTH--SVWGRY------
---------------------------------------------------TVSFLLIIT
QLGFCSVYFMFMADNLQQMVEEAHVTSNNCQPRK--NLVLTPILDIRFYMLAILPFLVLL
VFIQNLKVLSIFSTLANITTLGSMALIFEYIIQGI----PYPSNLPLM------------
ANWKTFLLFFGTAIFTFEGVGMV-L-----PLKNQMKDPQQFSFVLYLGMSLVI--SLYI
CLGTLGYMKFGSDTQASITLNLPNCWL--YQSAKLMYSVGIFFTYALQFHVPAEIIIPFA
ISQVSENWALFVDLSVRTAL--VCL----TCVSAILIPHLDLVISLVGSVSSSVLALIIP
PLLEIITFYSEDMS-CVTIAKDIMISILGLLGCIFGTYQALYDLTQPINHSV-ANSTGVY
A--------------------------

--------------------------------------------------MSVTKSAGSP
QVATTLNLD---LPESAK---KVQSQDPS-PANG--S-SSES------------------
-SKKTKG

PF01490 // ENSGT00390000011245_0_Domain_1 (128, 700)

ITGFQTLVHLVKGNMGTGILGLPLAVKNAGILMGPLSLLVMGLIACHCMHI--
LVRCAQ--RF-------CHR----------------------------------------
-----------------LNKPFMDYG--DTVMHGLASSPNAWLQNH--AHWGRRVVSFFL
IV---------------------------------------------------------T
QLGFCCVYIVFLADNLKQVVEAVNSTTISCHKNET-V-VLTPTMDSRLYMLSFLPILGLL
VFIRNLRVLTIFSLLANISMLVSLVIIAQYIIQEI----PDASQLPLV------------
ASWKTYPLFFGTAIFSFESIGVV-L-----PLENKMKDARGFPTILSLGMSIIT--TLYI
AIGALGYLRFGDDIKASITLNLPNCWL--YQSVKLLYVVGILCTYALQFYVPAEIIIPLA
VSQVSKRWALPVDLSIRLAL--VCL----TCMLAILIPRLDLVLSLVGSVSSSALALIIP
PLLEVVTYYGEGIS-PLTVTKDALISILGFMGFVVGTYQALDELIKSGNSPALSNST---
MFIQ-----------------------

--------------------------------------------------MGKTP-----
-------LLKEV------GKCDRNM-----FGQSKAS-SKGSSNSSSSSSSSSASP-KKG
PRREADALMF

PF01490 // ENSGT00390000011245_0_Domain_1 (131, 700)

IQIFIHLLKSNIGTGFLGLPLAVKNAGLLVGPVSLLAIGALTVHCMDI--
LLNCAC--HL-------TQR----------------------------------------
-----------------LQRSFVNYE--ETTMYSLETCPSPWLRTH--SVWGRY------
---------------------------------------------------VVSFLLIVT
QLGFCSVYFMFLADNLQQIMEEAHFTSNVCQPRQ--SLVMTSILDTRFYMLTILPFLILL
VLIQNPQVLSIFSTLATITTLSSLALIFEYLIQ-T----PHHSNLPLV------------
ANWKTFLLFFGTAIFTFEGVGMV-L-----PLKSQMKSPQQFPAVLYLGMSFVI--FLYI
CLGTLGYMKFGTDTQASITLNLPICWL--YQSVKLMYSVGIFFTYALQFHVPAEIIVPYV
VSRVSENWALFVDLTVRTAL--VCL----TCFSAVLIPRLDLVISLVGSVSSSALAIIIP
PLLEIATFYSENIS-CATIVKDIMISILGLLGCVLGTYQALYEMTQQTHFYT-ANSTRVH
I--------------------------

--------------------------------------------------MSVTERAGGP
QGTVALKLDSMSSPESAR---KLQNKDSG-FLDG--S-PSESQ-----------------
DLEKTK

PF01490 // ENSGT00390000011245_0_Domain_1 (127, 700)

GITLFQTLIHLLKGNMGTGVLGLPLAVKNAGILVGPLSLLVMGFVACHCMHI--
LVRCAQ--RF-------CQR----------------------------------------
-----------------FNKPFMDYG--DTVMHGLEATPSSWLQNH--AHWGRHIVSFFL
IV---------------------------------------------------------T
QLGFCCVYVVFLADNLKQVVEVINSTTTNCYNNET-V-TPAPTMDSRLYMLSFLPFLVLL
VFIRNLRVMTIFSMLANISMLVSLVIIAQYIAQGI----PDPSRLPLA------------
ASWKTYPLFFGTAIFSFESIGVV-L-----PLENKMEDSRHFPAILSLGMSIIT--ILYT
SIGTLGYLRFEEDIKASITLNLPNCWL--YLSVKLLYIIGILCTYALQFYVPAEIIIPFA
VSQVPKRWALPLDLFIRFAL--VCL----TCILAILIPRLDLVLSLVGSVSSSALALIIP
PLLEITTYYSEGIS-LLTITKDALISILGFVGFVAGTYQALHELLEPGDSLPFSNST---
TFIQ-----------------------

------------------------------------------------------------
-----------------MSTQRLRNEDYHDYSSTDVS-PEESPSEG-L-GNFS-PGSYQR
LGEN-N

PF01490 // ENSGT00390000011245_0_Domain_1 (127, 699)

STTWFQTLIHLLKGNIGTGLLGLPLAVRNAGILLGPLSLLVIGIVAVHCMGI--
LVKCAR--HL-------CLR----------------------------------------
-----------------MNKPFLDYG--DTVMYGLECSPSSWIRSH--SHWGRHIVDFFL
IV---------------------------------------------------------T
QLGFCCVYFVFLADNFKQVIEAANGTTTNCHNNET-V-VLMPTMDSRLYMLAFLPFLVLL
SFIRNLRILSIFSLLANVTMLVSLVTIYQFILQRI----PDPHHLPLV------------
ASWKTYPLFFGTAVFAFEGIGVV-L-----PLENKMKNSQKFPCILYLGMTIVT--VLYI
SLGSLGYLQFGAAIKASITLNLPNCWL--YQTVKLLYSIGIFFTYALQFYVAAEIMVPVI
VSRVPEHCTLLVDLCVRTAM--VCI----TCVLAILIPRLDLVLSLVGSMSSSALALIIP
PLLEVTTFYEEGLS-PLTIAKDVLISIFGFVGFVVGTYESLCELIFPSHSNTSTNS--TS
AFI------------------------

--------------------------------------------------MSVTKSAGSP
QVATTVKLDLVSSPESTK---KVESQDPS-LMNG--N-SSET------------------
-SKKTKG

PF01490 // ENSGT00390000011245_0_Domain_1 (128, 700)

ITGFQTLVHLVKGNMGTGILGLPLAVKNAGILMGPLSLLVMGLIACHCMHI--
LVKCAQ--HF-------CHR----------------------------------------
-----------------LNKPFMDYG--DTVMHGLEAGPNAWLRNH--AHWGRHIVSFFL
IV---------------------------------------------------------T
QLGFCCVYIVFLADNLKQVVEAVNGTTISCHYNET-L-VLTPTMDSRLYMLAFLPVLGLL
VFVRNLRVLTIFSLLANISMLVSLIIIAQYIVQGI----PDPSQLPLV------------
ASWKTYPLFFGTAIFSFESIGVV-L-----PLENKMKDARRFPTILSLGMSIVT--SLYI
AIGALGYLRFGDDIKASITLNLPNCWL--YQSVKLLYVVGILCTYALQFYVPAEIIIPLA
VSQVSKRWALPVDLSIRIAM--VCL----TCTLAILIPRLDLVLSLVGSVSSSTLALIIP
PLLEVTTYYGEGLS-PLTIIKDALISILGFVGFVVGTYQALDELIEPGNSLPVSNAT---
VFIQ-----------------------

------------------------------------------------------------
------------------------------------------------------------
---------

PF01490 // ENSGT00390000011245_0_Domain_1 (130, 702)

WFQTLIHLLKGNIGTGLLGLPLAVKNAGILMGPLSLLVMGIVAVHCMGI--
LVKCAH--HI-------CQR----------------------------------------
-----------------LHKPFVDYG--DTVMYGLEASPSSWLRTH--SLWGXXXXXXXX
XXXXXXXXX---------------------------------------------------
-------XXXXXXXXXXXXVAETISLSNRCQQNET-LKEMLPSLNLHLYMLTFLPFVILL
VFFHNFLMLSIFSTVGNIAILGSVALIFGYILQGI----PDPRNLPLV------------
ANWKTYPLFFGTAIFAFEGIGVV-L-----PLENKMKEPQHFPVILYVGMAIVT--FVYI
SLGCLGYLQFGAAIQASITLNLPNCWL--YQSVKLLYSVGIFFTYALQFYVPAEIIIPFF
VSWVTERWALVVDLSVRIVM--VCL----TCALAILVPRLDLVISLVGSLSSSTLALIIP
PLLEIITYYSEGIS-PLTIIKDLLISVLGFVGFVVGTYQSIYELIQPPVSPTFANL--TS
AFVQ-----------------------

------------------------------------------------------------
-----------------MSTQRLRNEDYHDYSSTDVS-PEESPSEG-L-GNFS-PGSYQR
LGEN-SS

PF01490 // ENSGT00390000011245_0_Domain_1 (128, 699)

MTWFQTLIHLLKGNIGTGLLGLPLAVKNAGLLLGPLSLLVIGIVAVHCMGI--
LVKCAH--HL-------CRR----------------------------------------
-----------------LNKPFLDYG--DTVMYGLECSPSTWVRSH--SHWGRRIVDFFL
IV---------------------------------------------------------T
QLGFCCVYFVFLADNFKQVIEAANGTTTNCNNNVT-V-IPTPTMDSRLYMLSFLPFLVLL
SFIRNLRVLSIFSLLANISMFVSLIMIYQFIVQRI----PDPSHLPLV------------
APWKTYPLFFGTAIFAFEGIGVV-L-----PLENKMKDSQKFPLILYLGMAIIT--VLYI
SLGSLGYLQFGANIKGSITLNLPNCWL--YQSVKLLYSIGIFFTYALQFYVAAEIIIPAI
VSRVPEHFELMVDLCVRTAM--VCV----TCVLAILIPRLDLVISLVGSVSSSALALIIP
PLLEVATYYGEGIS-PLTITKDALISILGFVGFVVGTYESLCELIQPSHSDSSANS--TS
AFI------------------------

------------------------------------------------------------
-----------------MSTQRLRNEDYHDYSSTDVS-PEESPSEG-L-NNLSSPGSYQR
FGQS-N

PF01490 // ENSGT00390000011245_0_Domain_1 (127, 453)

STTWFQTLIHLLKGNIGTGLLGLPLAVKNAGIVMGPISLLIIGIVAVHCMGI--
LVKCAH--HF-------CRR----------------------------------------
-----------------LNKSFVDYG--DTVMYGLESSPCSWLRNH--AHWGRRVVDFFL
IV---------------------------------------------------------T
QLGFCCVYFVFLADNFKQVIEAANGTTNNCHNNET-V-ILTPTMDSRLYMLSFLPFLVLL
VFIRNLRALSVFSLLANITMFVSLVMIYQFIVQIL-------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------

--------------------------------------------------MSVTKSAGAP
QGAVTLKLDSMSTPESAR---KLQNKDSR-FLDG--S-PSESP-----------------
GLEKTK

PF01490 // ENSGT00390000011245_0_Domain_1 (127, 452)

GITLFQTLVHLLKGNMGTGILGLPLAVKNAGILVGPLSLLVMGSVCCHCMLI--
LVKCAR--RL-------CQR----------------------------------------
-----------------LNKPFLDYG--DTVMHGLEASPSTWLQNH--AHWGRSIVSFFL
IV---------------------------------------------------------T
QLGFCCVYIVFLADNLKQVVEAINSTTNNCHSNET-V-IPTPTMDSRLYMLSFLPFLVLL
VFIRSLRVMTIFSMLANISMLVSLVIIAQYIAQ---------------------------
----------------------V-L-----PLENKMEDARHFPVILPLGLSIVI--ALYT
SIGALGYLRFGDDIKASITLNLPNCWL--YQSVNLLYIIGILCTYALQFYVAAEIIVPVA
VSQVPKRWALPLDLSIRLIL--SCL----TCILAILVPRLDLVLSLVGSVSSSALALIIP
PLLEISTYYSEGMS-PLTIIKDALISILGFVGFVAGTYHALHELMESGDSLPFSNST---
TFVQ-----------------------

------------------------------------------------------------
-----------------MSTQRLRNEDYHDYSSTDVS-PEESPSEG-L-NNFSSPGSYQR
FGES-N

PF01490 // ENSGT00390000011245_0_Domain_1 (127, 699)

STTWFQTLIHLLKGNLGTGLLGLPLAVKNAGILMGPLSLLVIGIVAVHCMSI--
LVRCAH--HF-------CRR----------------------------------------
-----------------LNKPFVDYG--DTVMYGLESSPSSWLRNH--AHWGRHIVDFFL
IV---------------------------------------------------------T
QLGFCCVYFVFLADNFKQVIEAANGTTNNCHNNET-V-ILTPTMDSRLYMLSFLPFLVLL
VFVRNLRALSIFSLLANITMLVSLVMLYQFIVQNI----PDPSHLPLV------------
ASWKTYPLFFGTAIFAFEGIGMV-L-----PLENKMKDPQKFPLILYMGMTIIT--ALYI
SLGCLGYLQFGANIQGSITLNLPNCWL--YQSVKLLYSIGIFFTYALQFYVPAEIIIPFF
VSRVPEHWELVVDLFVRTVL--VCL----TCVLAILIPRLDLVISLVGSVSSSALALIIP
PLLEITTYYSEGMS-PLTIAKDALISILGFVGFVVGTYEALYELIQPSNAPIFINS--TS
AFV------------------------

------------------------------------------------------------
-----------------MSTQRLRNEDYHDYSSTDVS-PDESPSEG-L-NNFSSSGSYQR
FGES-N

PF01490 // ENSGT00390000011245_0_Domain_1 (127, 699)

STTWFQTLIHLLKSNIGTGLLGLPLAVKNAGILMGPLSLLVMGIVAVHCMGI--
LVKCAH--HF-------CHR----------------------------------------
-----------------LNKSFVDYG--DTVMYGLESSPSSWLRNH--AHWGRHIVDFFL
IV---------------------------------------------------------T
QLGFCCVYFVFLAENFKQVIEAANATTNDCHSNET-V-ILTPTMDSRLYMLTFLPFLVLL
VFIRNLRVLSVFSLLANVSMLVSLVMIYQFIVQRI----PDPSRLPLV------------
ASWKTYPLFFGTAIFAFEGIGMV-L-----PLENKMKDPRKFPLILYVGMAIIT--ALYI
SLGSLGYLQFGANIQGSITLNLPNCWL--YQSVKLLYSFGIFFTYALQFYVPAEIIVPFF
VSRVPEHCELVVDLFVRTML--VCL----TCILAVLIPRLDLVISLVGSVSSSALALIIP
PLLEITTYYSEGMS-PLTITKDALISILGFVGFVVGTYEALYELMQPSDTPIFINS--TS
AFL------------------------

------------------------------------------------------------
-----------------MSTQRLRDEDYRDYSSTDAS-PEESPSEG-L-NNFSSSGSYMR
FGES-N

PF01490 // ENSGT00390000011245_0_Domain_1 (127, 698)

STTWFQTLIHLLKSNIGTGLLGLPLAVKNAGILMGPLSLLVIGLVAVHCMRI--
LVKCAH--HF-------CYR----------------------------------------
-----------------LNKPFVDYG--DTVMYSLEASPISWLRNH--AHWGRRMVDFFL
IV---------------------------------------------------------T
QLGFCCIYFVFLADNFKQVIEMANGTTNNCHNNET-V-ILTPTMDSRLYMLTFLPFMVLL
VFIRNLRALSIFSLLANITMAVSLVMIYQFTVQNI----PDPSHLPLV------------
ASWKTYPLFFGTAIFAFEGIGMV-L-----PLENKMKDPKKFSLILYVGMAIVT--ALYV
SLGILGYLHFGANIQGSITLNLPNCWL--YQSVKLLYSVGIFFTYALQFYVPAEIIIPFF
VARGPEHCELVIDLSVRTVL--VCL----TCILAILIPRLDLVISLVGSVSSSALALIIP
PLLEITTYYSEGMS-PITIVKDALISILGFVGFVVGTCLTLYELIQPSSAPIFINS--TS
AFV------------------------

------------------------------------------------------------
-----------------MSTQRLRNEDYHDYSSTDVS-PEESPSEG-L-NNLSSPGSYQR
FGQS-N

PF01490 // ENSGT00390000011245_0_Domain_1 (127, 699)

STTWFQTLIHLLKGNIGTGLLGLPLAVKNAGIVMGPISLLIIGIVAVHCMGI--
LVKCAH--HF-------CRR----------------------------------------
-----------------LNKSFVDYG--DTVMYGLESSPCSWLRNH--AHWGRRVVDFFL
IV---------------------------------------------------------T
QLGFCCVYFVFLADNFKQVIEAANGTTNNCHNNET-V-ILTPTMDSRLYMLSFLPFLVLL
VFIRNLRALSIFSLLANITMLVSLVMIYQFIVQRI----PDPSHLPLV------------
APWKTYPLFFGTAIFSFEGIGMV-L-----PLENKMKDPRKFPLILYLGMVIVT--ILYI
SLGCLGYLQFGANIQGSITLNLPNCWL--YQSVKLLYSIGIFFTYALQFYVPAEIIIPFF
VSRAPEHCELVVDLFVRTVL--VCL----TCILAILIPRLDLVISLVGSVSSSALALIIP
PLLEVTTFYSEGMS-PLTIFKDALISILGFVGFVVGTYEALYELIQPSNAPIFINS--TC
AFI------------------------

--------------------------------------------------MSVTKSTEGP
QGAVAIKLDLMSPPESAK---KLENKDST-FLDE--S-PSESA-----------------
GLKKTK

PF01490 // ENSGT00390000011245_0_Domain_1 (127, 700)

GITVFQALIHLVKGNMGTGILGLPLAVKNAGILMGPLSLLVMGFIACHCMHI--
LVKCAQ--RF-------CKR----------------------------------------
-----------------LNKPFMDYG--DTVMHGLEANPNAWLQNH--AHWGRHIVSFFL
II---------------------------------------------------------T
QLGFCCVYIVFLADNLKQVVEAVNSTTNNCYSNET-V-ILTPTMDSRLYMLSFLPFLVLL
VLIRNLRILTIFSMLANISMLVSLVIIIQYITQEI----PDPSRLPLV------------
ASWKTYPLFFGTAIFSFESIGVV------LPLENKMKNARHFPAILSLGMSIVT--SLYI
GMAALGYLRFGDDIKASISLNLPNCWL--YQSVKLLYIAGILCTYALQFYVPAEIIIPFA
ISRVSTRWALPLDLSIRLVM--VCL----TCLLAILIPRLDLVISLVGSVSGTALALIIP
PLLEVTTFYSEGMS-PLTIFKDALISILGFVGFVVGTYQALDELLKSEDSHPFSNST---
TFVR-----------------------

-----------------------------------------------------MS-----
-------LLGRD-----Y-NSELNS-----LDNGSQS-PLESSS-S-ITS-----E-NVH
PA-GEAG

PF01490 // ENSGT00390000011245_0_Domain_1 (128, 700)

LSMMQTLIHLLKCNIGTGLLGLPLAIKNAGLLVGPVSLLAIGVLTVHCMVI--
LLNCAQ--HL-------SQR----------------------------------------
-----------------LQKTFVNYE--EATMYSLETCPNTWLRTH--AVWGRWSSALSP
-RLECSGKI---------SAHC---NPHLQGS-SNS--PAQASRVAGIYRYTVSFLLVIT
QLGFCSVYFMFMADNLQQMMEEAHVTSNICQPRE--TLTLTPILDIRFYMLIILPFLISL
VFIQNLRALSVFSTLANISTLGSMALIFEYIMQGI----PYPSNLPLM------------
ANWKTFLLFFGTAVFTFEGVGMV-L-----PLKNQMKHPQQFSFVLYLGMSIVI--ILYI
LLGTLGYMKFGSDTQASIILNLPNCWL--YQSVKLMYSIGIFFTYALQFHVPAEIIIPFA
ISQVSESWAPFVDLSVRSAL--VCL----TCVSAILIPRLDLVISLVGSVSSSALALIIP
ALLEIVIFYSEDMS-CVTVAKDIMISILGLLGCIFGIYQALYELTQPISHSM-ANSTGVY
A--------------------------

------------------------------------------------------------
-----------------MSTQRLRNEDYHDYSSTDVS-PEESPSEG-L-GSFS-PGSYQR
LGEN-SS

PF01490 // ENSGT00390000011245_0_Domain_1 (128, 699)

MTWFQTLIHLLKGNIGTGLLGLPLAVKNAGLLLGPLSLLVIGIVAVHCMGI--
LVKCAH--HL-------CRR----------------------------------------
-----------------LNKPFLDYG--DTVMYGLECSPSTWVRNH--SHWGRRIVDFFL
IV---------------------------------------------------------T
QLGFCCVYFVFLADNFKQVIEAANGTTTNCNNNVT-V-IPTPTMDSRLYMLSFLPFLVLL
SFIRNLRVLSIFSLLANISMFVSLIMIYQFIVQRI----PDPSHLPLV------------
APWKTYPLFFGTAIFAFEGIGVV-L-----PLENKMKDSQKFPLILYLGMAIIT--VLYI
SLGSLGYLQFGANIKGSITLNLPNCWL--YQSVKLLYSIGIFFTYALQFYVAAEIIIPAI
VSRVPEHFELMVDLCVRTAM--VCV----TCVLAILIPRLDLVISLVGSVSSSALALIIP
PLLEVVTYYGEGIS-PLTVTKDALISILGFVGFVVGTYESLCELIQPSHSDSSTNS--TS
AFI------------------------

------------------------------------------------------------
-----------------MSTQRLRNENYHDYSSTDVS-PEESPSEG-L-SHLSSPGSYQR
FDQS-N

PF01490 // ENSGT00390000011245_0_Domain_1 (127, 700)

STTWFQTLIHLLKGNIGTGLLGLPLAVKNAGIVMGPVSLLVIGIIAVHCMGI--
LVKCAH--HF-------CRR----------------------------------------
-----------------LNKSFVDYG--ETVMYGLESSPCSCLRNH--AHWGRHVVDFFL
IV---------------------------------------------------------T
QLGFCCVYFVFLAENFKQVVEAANGTTNNCHNNET-V-ILTPTMDSRLYMLSFLPFLVLL
VFVRSLRALSVFSLLANITMLVSLIMIYQFIVQRI----PDPSNLPLV------------
APWKTYPLFFGTAIFAFEGIGMV-L-----PLENKMKDPQKFPLILYLGMAIVT--ILYL
SLGCLGYLQFGANIQGSITLNLPNCWL--YQSVKLLYSIGIFFTYALQFYVPAEIIIPFF
VSRAPEHCELVVDLFVRTVL--VCL----TCILAILIPRLDLVISLVGSVSSSALALIIP
PLLEVTTFYSEGMS-PLTIFKDAVISILGFVGFVVGTYVALYELIQPSNAPIFINS--TR
AFI------------------------

--------------------------------------------------MVKSS-----
-------LLRKD------GNRERNL-----FGVSKAP-SKSSSSS--NGSSSNVSP-QKD
PQGEADALLF

PF01490 // ENSGT00390000011245_0_Domain_1 (131, 700)

MQIFIHLLKSNIGTGFLGLPLAVKNAGLLVGPISLLAIGILTVHCMDI--
LLKCAS--HL-------TQR----------------------------------------
-----------------LQRSFVNYE--ETTMYSLETCPNPWLRTH--SVWGRY------
---------------------------------------------------IVSFLLIIT
QLGFCSVYFMFMADNLQQIVEEAHFTSNVCQPRT--SLVMTPVLDARFYMLTILPFLILL
VLVQNSQVLSIFSTLATITTLGSLALIFEYLIQ-I----PRHSSLPLV------------
ASWKTFLLFFGTAIFTFEGVGMV-L-----PLKSQMKSPQQFPAVLYLGMSFVI--FLYI
CLGTLGYMKFGSDTQASITLNLPNCWL--YQSVKVMYSVGIFFTYALQFHVPAEIIIPYV
ISRVSENWALFVDLTVRTAL--VCV----TCFSAVLIPRLDLVISLVGSVSSSALALIIP
PLLEIATFYSENIS-CVTIVKDIMISILGLLGCVFGTYQALYEMTQQARFPM-ANSTSGY
T--------------------------

--------------------------------------------------MSVTK---ST
EGAVAVKLDLMSPPESAK---KLENKDST-FLDE--S-PSESP-----------------
GLKKTK

PF01490 // ENSGT00390000011245_0_Domain_1 (127, 700)

GITVIQALIHLVKGNMGTGILGLSLAVKNAGILMGPLSLLVMGLIACHCMHI--
LVRCAQ--RF-------CKR----------------------------------------
-----------------LNKPFMDYG--DTVMHGLEASPSAWLQNH--AHWGRHIVSFFL
IV---------------------------------------------------------T
QLGFCCVYIVFLADNLKQVVEAVNSTTNNCYSNET-V-ILTPTMDSRLYMLSFLPFLVLL
VLIRNLRILTIFSMLANISMLVSLVIIAQYITQEI----PDPSRLPLV------------
ASWKTYPLFFGTAIFSFESIGVV-L-----PLENKMKNARHFPAILSLGMSIVT--SLYI
SIGTLGYLRFGDDIKASISLNLPNCWL--YQSVKLLYIAGILCTYALQFYVPAEIIIPFA
ISRVSTRWALPLDLSIRLAM--VCL----TCLLAVLIPRLDLVISLVGSVSSSALALIIP
PLLEVSTFYSEGMS-PLIIFKDALISILGFVGFVVGTYQALDELLKSGDSPLFSNST---
TFLR-----------------------

------------------------------------------------------------
-----------------MSTQRLRNEDYHDYSSTDVS-PEESPSEG-L-NNLSSPGSYQR
FGQS-N

PF01490 // ENSGT00390000011245_0_Domain_1 (127, 523)

STTWFQTLIHLLKGNIGTGLLGLPLAVKNAGIVMGPISLLVIGIVAVHCMGI--
LVKCAH--HF-------CRR----------------------------------------
-----------------LNKSFVDYG--DTVMYGLESSPCSWLRNH--AHWGRHVVDFFL
IV---------------------------------------------------------T
QLGFCCVYFVFLADNFKQVIEAANGTTNNCHNNET-V-ILTPTVDSRLYMLSFLPFLVLL
VFIRNLRALSVFSLLANITMLVSLIMIYQFIVQRI----PDPSHLPLV------------
APWKTYPLFFGTAIFAFEGIGMV-RAALFLTPGNKLKDPREFPIIYTWAWSHPV--T-SS
HISVLS---------RLGTSPVSLGRL--YQSVKLLYSIGIFFTYALQFYVPAEIIIPFF
VSRAPEHCELVVDLFVRTVL--VCL----TCILAILIPRLDLVISLVGSVSSSALALIIP
PLLEVTTFYSEGMS-PLTIFKDALISVLGFVGFVVGTYEALYELIQPSNAPIFINS--TR
AFI------------------------

------------------------------------------------------------
-----------------MSTQRLRNEDYQDYSSTDAS-PEESPSES-L-GNFS-PGTYQR
FGES-N

PF01490 // ENSGT00390000011245_0_Domain_1 (127, 699)

-TTWFQTLIHLLKGNIGTGLLGLPLAVKNAGILLGPLSLLVIGIVAVHCMGL--
LVKC-AR-HF-------CHR----------------------------------------
-----------------LNKPFVDYG--DTVMYGLESCPSPWLRNH--AHWGRRIVDFFL
IV---------------------------------------------------------T
QLGFCCVYFVFLADNFKQVIEAANGTTNNCHINET-V-ILTPTMDSRLYMVTFLPFLVLL
VFIRNLRVLSIFSLLANLSMLVSLVMIYQFIVQGI----PNPSNLPLV------------
APWKTYPLFFGTAIFAFEGIGVV-L-----PLENKMKDPQKFPLILYLGMAIVT--ALYI
SLGSLGYLQFGASIQGSITLNLPNCWL--YQSVKLLYSIGIFFTYGLQFYVPAEIIVPFF
VSRSPENCRLLVELVVRTLM--VCL----TCILAVLIPRLDLVISLVGSVSSSALALIIP
PILEVTTYASEGLS-PLTLAKDVLISLLGFVGFVVGTYEALSELIQPSAAPVSSNS--TG
AFASRAGYIL-----------------

MSSGIRKKKKETKQKEKK--------------------QLQEKN-RRSRNMLIK---EEE
KS-----KKIPQFRKLTMSTQRLRDEDYRDYSSTDAS-PEESPSEG-L-NNFSSSGSYMR
FGES-N

PF01490 // ENSGT00390000011245_0_Domain_1 (127, 672)

STTWFQTLIHLLKSNIGTGLLGLPLAVKNAGILMGPLSLLVIGLVAVHCMSI--
LVKCAH--RF-------CYR----------------------------------------
-----------------LNKPFVDYG--DTVMYGLEASPVSWLRNH--AHWGRHIVDFFL
IV---------------------------------------------------------T
QLGFCCIYFVFLADNFKQVIEMANGTTSNCHNNET-V-ILTPTMDSRLYMLTFLPFMVLL
VFVRNLRALSIFSLLANITMAVSLVMIYQFTVQNI----PDPSHLPLV------------
ASWKTYPLFFGTAIFAFEGIGMV-L-----PLENKMKDPKKFSLILYVGMTIVT--ALYI
SLGILGYLQFGANIQGSITLNLPNCWL--YQSVKLLYSVGIFFTYALQFYVPAEIIIPFF
VARGPEHCELVIDLSVRTVL--VCL----TCILAILIPRLDLVISLVGSVSSSALALIIP
PLLEITTYYSEGMS-PITIVKDALISILDSVSRSGTICNLFLPQ----------------
---------------------------

---------------------------M----------ATPN-------KDPICN-----
-------LELKTNPTVTFNSNPVNS-----PDNTWKLQKKECTT-------TAERP-GSV
ALKKV

PF01490 // ENSGT00390000011245_0_Domain_0 (126, 159)

KGITVFQTLIHLLKGNIGTGLLGLPLAVKNAGLLXXXXXXXXXXXXXXXXXXX--
XXX--XXXXX-------XXX----------------------------------------
-----------------VQKPFVDYG--DAVMYGLKTSPSSWLQNH--AVWGXXXXXXXX
XXXXXXXXXXXXXXX------------------------------------XXXXXXXXX
XXXXXX-----XXXXXXXXXXXXXXXXXXXXXXX----XXXX--XX-----X-------X
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDI----PDPRNLPLV------------
ADWNTYPLFFGTTIFAFESIGMXXX-----XXXXXXXXXXXXXXXXXXXXXXXX--X-X-
-XXXXXXXXXXXXXXXXXXXXXXXXXXXIYQFVKMLYSIGIFFTYALQFYVPAEIIIPLV
ISWVPEQWELLVDLSVRAIM--VCM----T------------------------------
------------------------------------------------------------
---------------------------

--------------------------------------------------MPVTKSASGP
QGTVDLKLDLRSPPKSAK---KLQSKDSS-FWDG--R-PSESP-----------------
GLEKT

PF01490 // ENSGT00390000011245_0_Domain_1 (126, 702)

KGITAFQTLVHLVKGNMGTGILGLPLAVKNAGILMGPLSLLAMGFISCHCMHI--
LVRCAQ--RF-------CHR----------------------------------------
-----------------LNKPFMDYG--DTVMYGLEASPSTWLRTH--AHWGRSIVSFFL
IV---------------------------------------------------------T
QLGFCCVYIVFLADNLKQVVEAVNGTTNNCHYNET-V-ILTPTMDSRLYMLSFLPFLVLL
ALIRNLRVLTIFSMLANISMLVSLMIITQYIVQEI----PDPSQLPLI------------
ASWKTYPLFFGTAIFSFESIGVV-L-----PLENKMKDARRFPAILSLGMSITT--ALYI
GIGSLGYLRFGDDIKASITLNLPNCWL--YQSVKLLYVVGILCTYALQFYVPAEIIIPFA
TSQVSKRWALPLDLSIRLAM--VCL----TCALAILIPRLDLVLSLVGSVSSSALALIIP
PLLEITTYYSEGMS-PLTIAKDALISILGFVGFVTGTYQALDELILSGHPLTFSNST---
AFIQ-----------------------

------------------------------------------------------------
-----------------MSTKRLRSEDYNDYSSTEVT-PDSSPPGG-L-SGFSGSSSYQR
FGEA-N

PF01490 // ENSGT00390000011245_0_Domain_1 (127, 630)

GTTWLQTLIHLLKGNIGTGLLGLPLAIRNAGIVMGPISLLVIGIIALHCMDI--
LVKCAH--HF-------CNK----------------------------------------
-----------------HQKPFVDYG--DAVMHGLEEAPSVWLRNH--SIWGRYLVGFFL
IL---------------------------------------------------------T
QLGFCCAYFVFLADNLKQVISAANGTTNNCNANET-A-LLAPTMSSQLYILCLLPFVILL
VFIQNLKILSIFSMLANLLMLSSLIMIFQYIVRDI----PDPTHLPMV------------
AQWKTFPLFFGTAIFAFEGIGVV-L-----PLENKMKNPQQFPIILYVGMGIVT--LLYF
SLGSLGYIRFGANIRASITLNLPNCWL--YQSVKLLYSIGIFFTYALQFYVPAEIIIPPA
LSQVPERWKLWLNLLLRVCL--VCV----T------------------------------
------------------------------------------------------------
---------------------------

------------------------------------------------------------
------------------------------------------------------------
-------------------------------------

PF01490 // ENSGT00390000011245_0_Domain_1 (158, 702)

LQLGPLCLVATGLVATRCMGV--
LVKWAL--HI-------CLR----------------------------------------
-----------------LYKPCKDCE--DTVMHVLEASSSAWLWDHAHSWWSHK------
----------------------------------------------------APMHLINA
CYGFQAFSFVFLLELYSQFLHEFRSLVAGLQPSMALILSLSPASLG--MSCCLRPLWETK
FFPHREKVSGKWSTLWNSSGHLSVGFISGFLCQKT----PDPSSLPLV------------
GNWKTQPLFLRMAFFAFKGVGVEDQ-----PTEAFMLDQAQFPLILYWGLSMIT--ILYI
SCGALGYLKIGATTEAGITLHLSNCWWLHFRAVKLLYLSGICLTYPLQSYMPAEIIVPFA
FPRCRSFCYLIMELYTCEYL--TCK----VCPMAILIPCLDLVLSLEGPVSSSTLALIIL
LFLET-TYYSADMNPISTISKDALSSILGFVGFMVGTYLALVKLNQPGDSVIFPNSTLAQ
---------------------------

--------------------------------------------------MSVTKKARAR
QEAATLTLDLMPSPQSTK---KLQDQESS-VLNR--S-ASERS-----------------
GLEETKG

PF01490 // ENSGT00390000011245_0_Domain_1 (128, 700)

ITGFQTLVHLVKGNMGTGILGLPLAVKNAGILMGPLSLLVMGFVACHCMHI--
LVRCAR--RF-------CCR----------------------------------------
-----------------LNKPFMDYG--ETVMHALEASPSTWLRSH--AAWGRHIVGFFL
IV---------------------------------------------------------T
QLGFCSVYIVFLADNLKQVIEAVNGTSNNCSSNQT-V-TPMPTMDSRLYMLTFLPFLALL
VFIRNLRVLTIFSLLANLSMLVSLVIIAQYIAQGI----PDPSQLPLV------------
ASWKTYPLFFGTAIFSFESIGVV-L-----PLENKMKDARHFPAILSLGMSIVT--TLYI
AIGALGYLRFGDDIKASITLNLPNCWL--YQSVKLLYILGILCTYALQFYVPAEIIIPFA
ISQVSERWALPVDLSTRLPGALVCFLSFPPGVLAVLIPRLDLVLSLVGSMSSSALALIIP
PLLEVTTYSSRGLG-PLTLAKDAIISVLGFVGFVVGTYQALDELIESGVSLPASNST---
LFVQ-----------------------

------------------------------------------------------------
-----------------MSTQRLRNEDYHDYSSTDVS-PEESPSEG-L-SNFS-SGSYQR
FGES-

PF01490 // ENSGT00390000011245_0_Domain_1 (126, 702)

NGTTWFQTLIHLLKGNIGTGLLGLPLAVKNAGILVGPLSLLLIGIVAVHCMGI--
LVKCAH--HF-------CHR----------------------------------------
-----------------LNKPFVDYG--DTVMYGLESSPSSWLRNH--AHWGRHVVDFFL
II---------------------------------------------------------T
QLGFCCVYFVFLADNFKQVIEAANGTTNNCHNNET-A-ILTPTMDSRLYMLSLLPFLVLL
VFIRNLRALSVFSLLANITMLVSLVMIYQFIVQKI----PNPSHLPLV------------
APWNTYPLFFGTAIFAFEGIGMV-L-----PLENKMKDPRKFPLILYGGMSIVT--ALYI
SLGCLGYLQFGAHVQGSITLNLPNCWL--YQSVKLLYSIGIFFTYALQFYVPAEIIIPFF
VSRVPEHCELVVDLFIRTVL--VCL----TCILAILIPRLDLVISLVGSVSSSALALIIP
PLLEITTYYSEGMS-PFTIAKDALISILGFVGFVAGTYQALYELIQPSNAPIIINS--TS
AFV------------------------

---------------------------------------------------MVKS-----
-------LLRKD------GNCERNL-----FGVSKAP-SKSSSSS---SSSSSISP-QKD
PQGEVDALLF

PF01490 // ENSGT00390000011245_0_Domain_1 (131, 700)

MQIFIHLLKSNIGTGFLGLPLAVKNAGLLVGPVSLLAIGVLTVHCMNI--
LLNCAS--HL-------TQR----------------------------------------
-----------------LQRSFVNYE--ETTMYSLETCPNPWLRTH--SAWGRY------
---------------------------------------------------IVSFLLIIT
QLGFCSVYFMFMADNLQQIVEEAHFTSNVCQSRK--SLVMTPVLDARFYMLTILPFLILL
VLVQNPQVLSIFSTLATITTLYSLALIFEYLIQ-T----PRHSNLPLV------------
ASWKTFLLFFGTAIFTFEGVGMV-L-----PLKSQMKSPQQFPAVLYLGMSFVI--FLYV
SLGTLGYMKFGSDTQPSITLNLPNCWL--YQSVKVMYSVGIFFTYALQFHVPAEIIIPYV
VSRVSENWALFVDMTVRTAL--VCL----TCFSAVLIPRLDLVISLVGSVSSSALALIIP
PLLEIATFYSENIS-CVTIVKDIIISILGLLGCVFGTYQALYEMTQQARFSM-ANSTSGY
T--------------------------

-----------------------------------------------------MS-----
-------LLGRD-----S-SSELNS-----LDDKSNS-PSGSNS-------STAPE-NGH
PA-GDVGL

PF01490 // ENSGT00390000011245_0_Domain_1 (129, 700)

SRMQTLIHLMKCNIGTGLLGLPLAIKNAGLLVGPISMLAIGVLTVHCMAI--
LVNCAQ--HI-------SQR----------------------------------------
-----------------MQKAFVNYG--EAAMYSLETCPNPWLRMH--AVWGRQSLTLLP
W-VECRG-V---------TAHS---NLQLLGL-SDSL--ASVSQAHNVPWYTVSFLLIIT
QLGFCCVYFMFMADNLQQMVEEAQVTSNSCEPRK--ILLLTPVLDIRFYMLTILPFLVLL
VFIQNLKVLSFFSTLANITTLGSMALIFEYIMQGI----PYPSNLPLA------------
ANWKTFVLFFGTAIFTFEGVGMV-L-----PLKNQMKNPQQFSFVLYLGMSLVI--SLYI
CLGTLGYMKFGSDTQASITLNLPNCWL--YQSVKLMYSIGIFFTYALQFHVPAEIIIPFA
ISQVSEQWALFVDLSVRTGL--VCL----TCISAILIPRLDLVISLVGSVSSSALALIIP
PILEIITFYSEDMN-CVTIAKDIMISILGLLGCIFGTYQSLHDLARPIHRSV-ANSTRVM
R--------------------------

------------------------------------------------------------
-----------------MSTQRLRNEDYHDYSSTDVS-PEESPSEG-L-NNLSSPGSYQR
FGES-N

PF01490 // ENSGT00390000011245_0_Domain_1 (127, 699)

STTWFQTLIHLLKGNIGTGLLGLPLAVKNAGILMGPLSLLVIGIVAVHCMGI--
LVKCAH--HF-------CRR----------------------------------------
-----------------LNKPFVDYG--DTVMYGLESSPCSWLRNH--AHWGRHVVDFFL
IV---------------------------------------------------------T
QLGFCCVYFVFLADNFKQVIEAANGTTNNCHNNET-V-ILTPTMDSRLYMLAFLPLLVLL
VFVRNLRALSVFSLLANISMLVSLVMIYQFIVQRI----PDPSHLPLV------------
APWKTYPLFFGTAIFAFEGIGMV-L-----PLENKMKDPQKFPLILYGGMIIIT--ALYI
SLGCLGYLQFGANIQGSITLNLPNCWL--YQSVKLLYSIGIFFTYALQFYVPAEIIIPFF
VARAPEHCELVVDLFVRTVL--VCL----TCILAILIPRLDLVISLVGSVSSSALALIIP
PLLEITTYYSEGMS-SLIIAKDALISLLGFVGFVVGTYEALYELIQPSNAPVFINI--TR
AFA------------------------

------------------------------------------------------------
-----------------MSTQRLRNEDYHDYSSTDVS-PEETPSEG-L-SNFS-PGSYQR
FGDS-

PF01490 // ENSGT00390000011245_0_Domain_1 (126, 702)

NGTTWFQTLVHLLKGNIGTGLLGLPLAVKNAGILMGPLSLLLMGIVAVHCMGI--
LVKCAHN-FC--------QX----------------------------------------
-----------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XTGGRHTVDFFL
IV---------------------------------------------------------T
QLGFCCVYFVFPADNFKQVIEAANGTTNNCHNNET-V-ILTPTMDSRLYMITFLPFLVLL
VFIRNLRALSVFSLLANITMLVSLVMIYQFIVQSI----PNPSRLPLV------------
ASWNTYPLFFGTAIFAFEGIGMV-L-----PLENKMKDPRKFPLILYGGMAIIT--ILYI
SLGSLGYLQFGAHIKGSVTLNLPNCWL--YQSVKLLYSVGIFFTYALQFYVPAEILVPFF
VSRAPERCGLLVDLSVRMAM--VCL----TCILAILIPRLDLVISLVGSVSSSALALIIP
PLLEITTYYSEGMS-PLTIAKDALISILGFVGFVVGTYQALYELIQPINGPIVINS--TS
AFV------------------------

--------------------------------------------------MPETKSAEGP
PGAVDLKMDLKSPPQSAE---KLQNKDSG-FLDG--S-PSESP-----------------
GLETT

PF01490 // ENSGT00390000011245_0_Domain_1 (126, 702)

KGITAFQTLVHLVKGNIGTGILGLPLAVKNAGILXXXXXXXXXXXXXXXXXX---
------------------------------------------------------------
-----XXXXXXXXXXXXLNKPFMDYG--DTVMHGLEASPSTWLRNH--AHWGRHIVSFFL
IV---------------------------------------------------------T
QLGFCCVYIVFLADNLKQVVEAVNGTTSNCHDNMT-V-ILMPTMDSRLYMLTFLPFLVLL
ALIRNLRILTIFSLLANISMLVSLIIIIQYITQGI----PDPSQLPLV------------
ANWKTYALFFGTAIFSFESIGVV-L-----PLENKMKDARRFPVILSLGMSIIT--ALYI
SIGTLGYLRFRNDIKASITLNLPNCWL--YQSVKLLYIIGILCTYSLQFYVPAEIIIPFA
ISKVSQRWALPLDLSIRLVM--ACL----TCILAILVPRLDLVLSLVGSVSSSALALIIP
PLLEIVTYYSEGMS-PLTIIKDALISILGFVGFVMGTYQALDELIQSEHLLTFPNST---
TFT------------------------

------------------------------------------------------------
-----------------MSTQRLRNEDYHDYSSTDVS-PEESPSDG-L-SNFS-SGSYQR
FGEG-

PF01490 // ENSGT00390000011245_0_Domain_1 (126, 702)

NSTTWFQTLIHLLKGNIGTGLLGLPLAVRNAGLLMGPLSLLVIGIVAVHCMGI--
LVKCAP--H--------CRR----------------------------------------
-----------------MNKPFVDYG--DTVMYGLESSPSSWLRNH--AHWGRHVVDFFL
IV---------------------------------------------------------T
QLGFCCVYFVFLADNFKQVIEAANGTTNDCHNNET-V-VLTPTMDSRLYMLSFLPFLVLL
VFIRNLRILSIFSLLANLSMLVSLIMIYQFIVQAI----PNPSNLPLV------------
APWKTYPLFFGTAIFAFEGIGMV-L-----PLENKMKDPRKFPVILYTGMAIVT--TLYI
SLGCLGYLQFGAKIQGSITLNLPNCWL--YQSVKLLYSIGIFFTYAIQFYVPAEIVIPFF
VSQVPEHCELVVDLFVRTVM--VCL----TCVLAILIPRLDLVISLVGSVSSSALALIIP
PLLEITTFYSEGLS-PLTIAKDALISILGFMGFVVGTYEALYELIQPSNIPIIVNA--TS
AFA------------------------

------------------------------------------------------------
-----------------MSTQRLRNGDYHDYSSTGAS-PEESPSEG-R-SSFS-PGSYQR
FGES-S

PF01490 // ENSGT00390000011245_0_Domain_1 (127, 699)

STTWFQTLIHLLKGNIGTGLLGLPLAVKNAGILMGPLSLLVIGIVAVHCMGI--
LVKCAH--HL-------CCR----------------------------------------
-----------------LNKPYLDYG--DTVMHGLESSPSAWLRNH--AHWGRRTVDFFL
IV---------------------------------------------------------T
QLGFCCVYFVFLADNFKQVIEAANGTTNNCHNNET-V-ILMPTMDSRLYMLTFLPFLVLL
AFIRNLRILSIFSLLANISMLVSLVMIYQFIVQRI----PDPSHLPLV------------
APWKTYPLFFGTAIFAFEGIGMV-L-----PLENKMKDPRKFPLILYVGMAIVT--ALYI
SLGSLGYLQFGASIQGSITLNLPNCWL--YQSVKLLYSIGIFFTYALQFYVPAEIIVPFF
VSRAPEHCELVVDLFVRTAL--VCV----TCVLAILIPRLDLVISLVGSVSSSALALIIP
PLLEVTTYYTEGMS-PLTIAKDALISVLGFVGFVVGTYEALYELIQPSSGPIATNS--TS
AFM------------------------

--------------------------------------------------MSVTKSAGSP
QVAATVKLDLVSFPESAK---KVQSQDPN-PVNG--S-SSES------------------
-SEKTKG

PF01490 // ENSGT00390000011245_0_Domain_1 (128, 700)

ITGFQTLVHLVKGNMGTGILGLPLAVKNAGILMGPLSLLVMGLIACHCMHI--
LVRCAQ--RF-------CHR----------------------------------------
-----------------LNKPFMDYG--DTVMHGLASSPNTWLQSH--AHWGRHVVSFFL
IV---------------------------------------------------------T
QLGFCCVYIVFLADNLKQVVEAVNSTTISCHKNET-V-VLTPTIDSRLYMLAFLPVLGLL
VFIRNLRVLTIFSLLANVSMLVSLVIIAQYIIQGI----PDPSQLPLV------------
ASWKTYPLFFGTAIFSFESIGVV-L-----PLENKMKDARRFPTILSLGMSIIT--TLYI
AIGALGYLRFGDDIKASITLNLPNCWL--YQSVKLLYVVGILCTYALQFYVPAEIIIPLA
VSQVSKRWALPVDLSIRLAL--VCL----TCMLAILIPRLDLVLSLVGSVSSSALALIIP
PLLEVTTYYGEGMS-PLTITKDALISILGFMGFVVGTYQALDELIRSGNSLPLSNST---
MFIQ-----------------------

--------------------------------------------------MPVTKSAGGP
QGTVDLKLDLRSPPKSAK---KLQSKDSS-FWDG--H-PSESP-----------------
GLKKTK

PF01490 // ENSGT00390000011245_0_Domain_1 (127, 700)

GITAFQTLVHLVKGNMGTGILGLPLAVKNAGILMGPLSLLAMGFTACHCMHI--
LVRCAQ--HF-------CHR----------------------------------------
-----------------LNKPFMDYG--DTVMHGLEASPSAWLRTH--AHWGRNIVSFFL
IV---------------------------------------------------------T
QLGFCCVYIVFLADNLKQIVEAVNGTTNSCHYNET-V-ILTPTMDSRLYMLSFLPFLVLL
VLIRNLRVLTIFSMLANISMLVSLIIITQYIVQEI----PDPSQLPLV------------
ASWKTYPLFFGTAIFSFESIGVV-L-----PLENKMKDARRFPAILSLGMSIVT--SLYI
GIGSLGYLRFGDDIKASVTLNLPNCWL--YQSVKLLYIIGILCTYALQFYVPAEIIIPFA
TSQVAKRWALPLDFSIRVAM--VCL----TGTLAILIPRLDLVLSLVGSVSSSALALIIP
PLLEITTYYSEGMS-PLTIAKDALISILGLMGFVVGTYQALNELILSGQPLPFSNST---
IFIQ-----------------------

--------------------------------------------------MGKTP-----
-------LLRED------GRCQRNT-----FGGSKAS-SKGSSSSS---SNNTVSS-KKK
PRRKADALMF

PF01490 // ENSGT00390000011245_0_Domain_1 (131, 700)

IQIFIHLLKSNIGTGFLGLPLAVKNAGLLVGPVSLLAIGALTVHCMDI--
LLNCAC--HL-------TSR----------------------------------------
-----------------LQRSFVNYE--ETTMYSLETCPSPWLRTH--SVWGRY------
---------------------------------------------------VVSFLLIVT
QLGFCSVYFMFMADNLQQIVEEAHFTSNVCQPRQ--SLVMTSILDTRFYMLTILPFLILL
VLVQNPQVLSIFSTLATITTLSSLALIFEYLIQ-I----PHHSHLPLV------------
ASWKTFLLFFGTAIFTFEGVGMV-L-----PLKSQMKSPQQFPAVLYLGMSFVI--FLYI
CLGTLGYMKFGADTQASITLNLPNCWL--YQSVKLMYSVGIFFTYALQFHVPAEIIVPYV
VSRASENWALFIDLTVRAAL--VCL----TCFSAVLIPRLDLVISLVGSVSSSALALIIP
PLLEIATFYSENIS-CTTIAKDIMISILGLLGCVLGTYQALYEMTQQSRFPM-LNSTNVH
T--------------------------

--------------------------------------------------MPVTKNAEGP
QEAATLKLDLMPSPKSTK---KLQNKDSG-FLDG--S-SSESS-----------------
GLEKTK

PF01490 // ENSGT00390000011245_0_Domain_1 (127, 700)

GITAFQTLVHLVKGNMGTGVLGLPLAVKNAGILVGPLSLLVMGFVACHCMHI--
LVRCAQ--HF-------CRR----------------------------------------
-----------------LNKPFMDYG--ETVMLGLEGSPSGWLRSR--AHWGRHIVSVFL
VV---------------------------------------------------------T
QLGFCCVYIVFLADNLKQVIEAVNGTTHNCHNNKT-M-TLTPTMDSRLYMLAFLPFLSLL
VLIRNLRVLTIFSLLANVSMLVSLVIIAQHITQGI----PDPSRLPLA------------
TSWKTYPLFFGTAIFSFESIGVV-L-----PLENKMKDARHFPAILSLGMSIIT--ALYI
AIGALGYLRFGDNIRASITLNLPNCWL--YQSVKLLYIVGILCTYALQFYVPAEIIVPFT
VSRVSERWALPVDLSVRLAM--VCL----TCMLAILIPRLDLVLSLVGSVSSSALALIIP
PLLEIATYSSEGLC-PLTIAKDALISILGFVGFVTGTYQALDELIESEESLPSSNST---
IFNQ-----------------------

-----------------------------------------------------MS-----
-------LLGRN-----Y-NSELNS-----LDNRSQS-PSESSS-S-ITS-----E-NVH
PA-GEAG

PF01490 // ENSGT00390000011245_0_Domain_1 (128, 700)

LSMMQTLIHLLKCNIGTGLLGLPLAIKNAGLLVGPVSLLAIGVLTVHCMVI--
LLNCAQ--HL-------SQR----------------------------------------
-----------------LQKTFVNYG--EATMYSLETCPNTWLRTH--AVWGRWSSAVSH
-RLECSGKI---------SAHC---NPHLQGS-SDS--PAQAS-VAEIYRYTVSFLLIIT
QLGFCSVYFMFMADNLQQMVEEAHVTSNICQPRE--ILALTPILDIRFYMLTILPFLILL
VFIQNLKVLSVFSTLANITTVGSMALIFEYIMQGI----PYPSNLPLM------------
ANWKTFLLFFGTAIFTFEGVGMV-L-----PLKNQMKHPQQFSFVLYLGMSIVI--ILYI
FLGTLGYMKFGSDTQASITLNLPNCWL--YQSVKLMYSIGIFFTYALQFHVPAEIIIPFA
VSQVSESWALFVDLSVRSGL--VCL----TCVSAILIPRLDLVISLVGSVSSSTLALIIP
ALLEIVIFYSEDMS-CVTLAKDIMISILGLLGCIFGTYQALYELTQPINHSM-ANSTGVY
A--------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------VLPQVVSAANGTTNDCSSNRT

PF01490 // ENSGT00390000011245_0_Domain_1 (396, 503)

-V-VMTPTMDSRLYMLSILPFVVLL
TFIQNLKVLSIFSMLANVAMLVSLVVIYQYIVRDI----PDPRNLPLA------------
AAWKTYPLFFGTAIFAFEGIGVV-------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------

------------------------------------------------------------
-----------------MSTQRLRNEDYHDYSSTDVS-PEESPSEG-L-NNLSSPGSYQR
FGQS-N

PF01490 // ENSGT00390000011245_0_Domain_1 (127, 699)

STTWFQTLIHLLKGNIGTGLLGLPLAVKNAGIVMGPISLLVIGIVAVHCMGI--
LVKCAH--HF-------CRR----------------------------------------
-----------------LNKSFVDYG--DTVMYGLESSPCSWLRNH--AHWGRHVVDFFL
IV---------------------------------------------------------T
QLGFCCVYFVFLADNFKQVIEAANGTTNNCHNNET-V-ILTPTMDSRLYMLSFLPFLVLL
VFIRNLRALSVFSLLANITMLVSLIMIYQFIVQRI----PDPSHLPLV------------
APWKTYPLFFGTAIFAFEGIGMV-L-----PLENKMKDPRKFPLILYLGMVIVT--ILYI
SLGCLGYLQFGANIQGSITLNLPNCWL--YQSVKLLYSIGIFFTYALQFYVPAEIIIPFF
VSRAPEHCELVVDLFVRTVL--VCL----TCILAILIPRLDLVISLVGSVSSSALALIIP
PLLEVTTFYSEGMS-PLTIFKDALISVLGFVGFVVGTYEALYELIQPSNAPIFINS--TR
AFI------------------------

--------------------------------------------------MSVTK---ST
EGAVAVKLDLMSPPESAK---KLENKDST-FLDE--S-PSESP-----------------
GLKKTK

PF01490 // ENSGT00390000011245_0_Domain_1 (127, 700)

GITVIQALIHLVKGNMGTGILGLSLAVKNAGILMGPLSLLVMGLIACHCMHI--
LVRCAQ--RF-------CKR----------------------------------------
-----------------LNKPFMDYG--DTVMHGLEASPSAWLQNH--AHWGV-------
------------------------------------------------------------
-------------------VEAVNSTTNNCHSNET-V-MLTPTMDSRLYMLSFLPFLVLL
VLIRNLRILTIFSMLANISMLVSLVIITQYITQEI----PDPSRLPLV------------
ASWKTYPLFFGTAIFSFESIGVV-L-----PLENKMKNARHFPAILSLGMSIVT--SLYI
SIGTLGYLRFGDDIKASISLNLPNCWL--YQSVKLLYIAGILCTYALQFYVPAEIIIPFA
ISRVSTRWALPLDLSIRLAM--VCL----TCLLAVLIPRLDLVISLVGSVSSSALALIIP
PLLEVSTFYSEGMS-PLTIFKDALISILGFVGFVVGTYQALDELLKSGDSPLFSNST---
TFLQ-----------------------

-----------------------------------------------------ML-----
-------LLGRD-----Y-NSELNS-----LDNGPQS-PSESSS-S-ITS-----E-NVH
PA-GEAG

PF01490 // ENSGT00390000011245_0_Domain_1 (128, 700)

LSMMQTLIHLLKCNIGTGLLGLPLAIKNAGLLVGPVSLLAIGVLTVHCMVI--
LLNCAQ--HL-------SQR----------------------------------------
-----------------LQKTFVNYG--EATMYGLETCPNTWLRAH--AVWGRWNLALSP
-RLECSGNI---------SAHC---NPHLQGS-SNS--PAQASQVAGIYRYTVSFLLVIT
QLGFCNVYFMFMADNLQQMVEEAHVTSNICQPRE--SLTLTPILDIRFYMLIILPFLILL
VFIQNLKVLSIFSTLANITTLGSMALIFEYIMQGI----PYPSNLPLM------------
ANWKTFLLFFGTAIFTFEGVGMV-L-----PLKNQMKHPQQFSFVLYLGMSIVI--ILYI
LLGTLGYMKFGSDTQASITLNLPNCWL--YQSVKLMYSIGIFFTYALQFHVPAEIVIPFA
ISQVSESWALFVDLSVRSAL--VCL----TCVSAILIPRLDLVISLVGSVSSSALALIIP
ALLEIVIFYSEDMS-CVTIAKDIMISIVGLLGCIFGTYQALYELPQPISHSM-ANSTGVH
A--------------------------

--------------------------------------------------MGKMP-----
-------LLREV------GKCQRNM-----FGRSKAS-SKGSSNSRS---SSSTSP-KKG
PRREADALMF

PF01490 // ENSGT00390000011245_0_Domain_1 (131, 700)

IQIFIHLLKSNIGTGFLGLPLAVKNAGLLVGPVSLLAIGALTVHCMDI--
LLNCAC--HL-------TQR----------------------------------------
-----------------LQRSFVNYE--ETTMYSLETCPSPWLRTH--SVWGRY------
---------------------------------------------------VVSFLLIVT
QLGFCSVYFMFLADNLQQIMEEAHFTSNVCQPRQ--SLVMTSILDTRFYMLTILPFLILL
VLIQNPQVLSIFSTLATITTLSSLALIFEYLIQ-T----PHHSNLPLV------------
ANWKTFLLFFGTAIFTFEGVGMV-L-----PLKSQMKSPQQFPAVLYLGMSFVI--FLYI
CLGTLGYMKFGTDTQASITLNLPICWL--YQSVKLMYSVGIFFTYALQFHVPAEIIVPYV
VSRVSENWALFVDLTVRTAL--VCL----TCFSAVLIPRLDLVISLVGSVSSSALAIIIP
PLLEIATFYSENIS-CATIVKDIMISILGLLGCVLGTYQALYEMTQQTHFYM-ANSTRVH
I--------------------------

-----------------------------------------------------MS-----
-------LLGRD-----Y-NSELNS-----LDNRSQS-PSESSS-S-ITS-----E-NVH
PA-GEAG

PF01490 // ENSGT00390000011245_0_Domain_1 (128, 700)

LSMMQTLIHLLKCNIGTGLLGLPLAIKNAGLLVGPVSLLAIGVLTVHCMVI--
LLNCAQ--HL-------SQR----------------------------------------
-----------------LQKTFVNYG--EATMYSLETCPNTWLRTH--AVWGRWSSAVSH
-RLECSGKI---------SAHC---NPHLQGS-SDS--PTQAS-VAEIYRYTVSFLLIIT
QLGFCSVYFMFMADNLQQMVEEAHVTSNICQPRE--ILALTPILDIRFYMLTILPFLILL
VFIQNLKVLSVFSTLANITTVGSMALIFEYIMQGI----PYPSNLPLM------------
ANWKTFLLFFGTAIFTFEGVGMV-L-----PLKNQMKHPQQFSFVLYLGMSIVI--ILYI
FLGTLGYMKFGSDTQASITLNLPNCWL--YQSVKLMYSIGIFFTYALQFHVPAEIIIPFA
VSQVSESWALFVDLSVRSGL--VCL----TCVSAILIPRLDLVISLVGSVSSSALALIIP
ALLEIVIFYSEDMS-CVTLAKDIMISILGLLGCIFGTYQALYELTQPINHSM-ANSTGVY
A--------------------------

----------------------------------------------------MPMTKGGS
QGSATFKLDLVSSPKITK---KRQNKEPS-LLNG--N-SSAS------------------
-SKKTK

PF01490 // ENSGT00390000011245_0_Domain_1 (127, 454)

GITAFQTLIHLVKGNMGTGILGLPLAVKNAGILMGPLSLLMMGLIPCHCMHILI
LVRCAQ--HF-------CRR----------------------------------------
-----------------LNKPFMDYG--DTVMHGLEASPSTWLQSH--AHWGRHIVSFFL
II---------------------------------------------------------T
QLGFCCVYVVFLADNLK-------------------------------------------
--------------------------------QGI----PDPSQLPLV------------
ANWKTYPLFFGTAIFSFESIGVV-L-----PLENKMKDPRHFPAILSLGMFIVT--ALYI
TVGALGYLRFEDGIKASITLNLPNCWL--YQLVKVLYIMGILCTYALQFYVPAEIIIPVA
VSRVSKHWTLSVDLSTRLAM--VCL----TCMLAILIPRLDLVISLVGSVSSSALALIIP
PLLEITTFYSEGMS-PLTILKDALISILGFVGFVAGTYQTLNELIKPGDFLSLSNST---
TFIQ-----------------------

-----------------------------------------------------TS-----
-------LLGRD-----E-NSEPNS-----LDNESKS-LSESSSN-------TTSE-DVP
AAEEA

PF01490 // ENSGT00390000011245_0_Domain_1 (126, 702)

SGLSMMQTLIHLLKCNIGTGLLGLPLAMKNAGLLVGPISLLAIGVLTVHCMVI--
LLNCAH--HL-------SQR----------------------------------------
-----------------LQKTFVNYG--EAMMYGLKTCQNAWLRTH--SVWGRG------
-------------------------------------------------RYIVSFLLIIT
QLGFCSVYFMFIADNLQQMVEEAHMVSNSCHPRK--ILVLTPILDIRFYMLTILPFLILL
VFIQNLKLLSIFSTLANITTLGSMALIFEYIVQGI----PDPSNLPLM------------
ASWETFLLFFGTAIFTFEGVGMV-L-----PLKNQMKHPQQFSFVLYLGMSLII--ILYV
CLGTLGYMKFGSSTQASITLNLPNCWL--YQSVKLMYSIGIFFTYALQFHVPAEIIIPIV
ISQVSESWALFADLSVRTAL--VCL----TCVSAILIPRLDLVISLVGSVSSSALALIIP
PLLELITFYPEDMS-CITIAKDIMISILGLLGCVFGTYQALYELIQPINHSI-ANSTGV-
------------YA-------------

--------------------------------------------------MLKTS-----
-------LLGRD-----F-NSEPSP-----LDNRSKS-LSESRGS-------VASE-NVH
PTEEANR

PF01490 // ENSGT00390000011245_0_Domain_1 (128, 694)

LSIMQTLVHLLKCNIGTGLLGLPLAMKNAGLLVGPISLLAIGILTVHCMVI--
LLNCAH--HL-------SQR----------------------------------------
-----------------LQKTFVNYG--EAMMYSLETCPNAWLRTH--SVWGR-------
--------------------------------------------------YTVSFLLITT
QLGFCSVYFMFMADNLQQMVEEAHVTSNNCQPRK--ILALTPILDIRFYMLTILPFVVLL
VFIQNLRMLSIFSTLANITTLGSMALIFEYIIKEI----PDPSSLPLM------------
ASWKTFLLFFGTAIFTFEGVGMV-L-----PLKNQMKHPQHFSFVLYLGMSLVI--ILYI
CLGTLGYMKFGSSTQASITLNLPNCWL--YQSVKLMYSIGIFFTYALQFHVPAEIIIPFV
ISQVSESWTLLIDLSVRTAL--VCL----TCVSAILIPRLDLVISFVGSVSSSALALIIP
PLLELITFYPEDMS-CVTIAKDIMISILGLLGAAGKMR-SMHRKYSRHASSL-ANHENTR
LRTCHRPEETGVA--------------

--------------------------------------------------MPGTKSASSS
QDAVDLKLDLGSPPESAK---KLQNKDFS-LLNG--S-PSELP-----------------
SLEKT

PF01490 // ENSGT00390000011245_0_Domain_1 (126, 702)

KGITAFQTLVHLVKGNMGTGILGLPLAVKNARILXXXXXXXXXXXXXXXXXX---
------------------------------------------------------------
-----XXXXXXXXXXXXLNRPFMDYA--DTVMHGLEASPSAWLRKH--AHWGRHMVSFFL
IL---------------------------------------------------------T
QLGFCCVYIVFLADNLKQVVEAINGTTNNCHYNET-V-ILTPTLDSRLYMLAFLPVLVLL
ALIRNLRVLSVFSMLANLSMLLSLVIIAQYSVQEI----PDPSRLPLI------------
ASWKTYSLFFGTAIFSFESIGVV-L-----PLENKMKNTRRFPAILSLGMFIIT--ALYI
GIGVLGYMRFENDIKASITLNLPNCWL--YQSVKLLYVAGILCTYTLQFYVPAEIIIPFA
ISQVSKRWALLLDLSIRFTM--VCL----TCILAILIPRLDLVISLVGSVSSSALALIIP
PLLEIATYYSEGMS-PLTIVKDALISILGFMGFVAGTYQALDELIQPGHSVTFSNST---
MLIQ-----------------------

------------------------------------------------------------
-----------------MSTQRLRNEDYPDYSSTDVS-PDESPSEG-L-NNFSSPGSYQR
FGES-

PF01490 // ENSGT00390000011245_0_Domain_1 (126, 702)

SSTTWFQTLIHLLKGNIGTGLLGLPLAVKNAGILMGPLSLLVIGIVAVHCMSI--
LVKCAR--HF-------CQR----------------------------------------
-----------------LNKPFVDYG--ETVMYGLESTSSSWLRNH--AHWGRHIVDFFL
IV---------------------------------------------------------T
QLGFCCVYFVFLADNFKQXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXX-XXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRI----PNPSHLPLV------------
APWKTYPLFFGTAIFAFEGIGMV-L-----PLENKMKDPRKFPLILYVGMAIIT--TLYI
SLGCLGYLQFGADIQGSITLNLPNCWL--YQSVKLLYSIGIFFTYALQFYVPAEIIIPFF
VSRVPEHWELVVDLFVRTLL--VCL----TCILAILIPRLDLVISLVGSVSSSALALIIP
PLLEITTYYSEGMS-PLAITKDALISILGFVGFVVGTYEALYELTQPSNAPIFINS--TS
AFA------------------------

--------------------------------------------------MSVTKSDGSP
QGAVALKLDLVPPPESAK---KPENTDSS-FLDG--S-PSESP-----------------
GLEKTKG

PF01490 // ENSGT00390000011245_0_Domain_1 (128, 700)

ITGFQALVHLVKGNMGTGILGLPLAVKNAGILVGPLSLLAMGVIACHCMHI--
LVRCAQ--RF-------CHR----------------------------------------
-----------------LNKPFMDYG--HTVMHGLEASPSAWLRTH--AHWGRRIVSFFL
IV---------------------------------------------------------T
QLGFCCVYIVFLADNLKQVVEAVNSTTHNCHSNET-V-TLTPTMDSRLYMLAFLPVLVLL
VFIRNLRILTTFSMLANISMLVSLVIITQYIVQGI----PDPSRLPLG------------
ASWKTYPLFFGTAIFSFESIGVV-L-----PLENKMKDARRFPAILYLGMSIVT--SLYI
GIGALGYLRFGDDIKASITLNLPNCWL--YQSVKLLYIVGILCTYALQFYVPAEIIIPLA
ISQVSPRWALLLDLSIRLAM--VCL----TCVLAILIPRLDLVLALVGSVSSSALALIIP
PLLEITTYYSEGMN-PLTIAKDALISLLGFVGFVVGTYQALEELLEPGPSRPFSNST---
ICIQ-----------------------

--------------------------------------------------MPMTKNARDH
QEAATLTLDAMPPPQGTK---KLQNKGSS-FSGG--S-PSEAL-----------------
GLEKTKG

PF01490 // ENSGT00390000011245_0_Domain_1 (128, 700)

ITGFQTLVHLVKGNMGTGILGLPLAVKNAGILMGPLSLLVMGFVAGHCMHV--
LVRCAQ--RF-------CRR----------------------------------------
-----------------LNKPFMDYG--ETVMRALEASPSAWLQTR--ARWGRHLVSFFL
VV---------------------------------------------------------T
QLGFCCVYIVFLADNLKQVVEAANGTTNNCHSNET-A-VLTPTMDSRLYMLAFLPVLVLL
VLVRNLRVLTGFSLLANISMLVSLLITAQHIAQGI----PDPSRLPLV------------
ASWKTYPLFFGTAIFSFESIGVV-L-----PLENKMKDARHFPAILTLGMSIIT--ALYI
GIGALGYLRFGDDVRASITLNLPNCWL--YQAVKLLYIVGILCTYALQFYVPAEIVIPPA
TSRVSERWALPVDLSIRLAM--VCL----TCILAVLIPRLDLVLSLVGSVSSSALALIIP
PLLEVTTYSSEGLS-PLMLTKDVLISILGFVGFVAGTYQALDELMGSGDSLLPSNST---
MVTQ-----------------------

--------------------------------------------------MSVTKSTEGP
QGAVAIKLDLMSPPESAK---KLENKDST-FLDE--S-PSESA-----------------
GLKKTK

PF01490 // ENSGT00390000011245_0_Domain_1 (127, 700)

GITVFQTLIHLVKGNMGTGILGLPLAVKNAGILMGPLSLLVMGFIACHCMHI--
LVKCAQ--RF-------CKR----------------------------------------
-----------------LNKPFMDYG--DTVMHGLEANPNAWLQNH--AHWGRHIVSFFL
IV---------------------------------------------------------T
QLGFCCVYIVFLADNLKQVVEAVNSTTNNCYPNET-V-ILTPTMDSRLYMLSFLPFLVLL
VLIRNLRILTIFSMLANISMLVSLVIIIQYITQEI----PDPSRLPLV------------
ASWKTYPLFFGTAIFSFESIGVV------LPLENKMKNARHFPAILSLGMSIVT--SLYI
GMAALGYLRFGDDIKASISLNLPNCWL--YQSVKLLYIAGILCTYALQFYVPAEIIIPFS
ISRVSTRWALPLDLSIRLVM--VCL----TCLLAILIPRLDLVISLVGSVSGTALALIIP
PLLEVTTFYSEGMS-PLTIFKDALISILGFVGFVVGTYQALDELLKSEDSHPFSNST---
TFVR-----------------------

------------------------------------------------------------
-----------------MSTQRLRNEDYHDYSSTDVS-PEESPSEG-L-SNF-SPGSYQR
FGES-S

PF01490 // ENSGT00390000011245_0_Domain_1 (127, 700)

STTWFQTLIHLLKGNIGTGLLGLPLAVKNAGLLMGPLSLLVIGIVAVHCMGI--
LVKCAH--HF-------CRR----------------------------------------
-----------------LNKPFVDYG--DTVMYGLESSPSSWLRNH--AHWGRHIVDFFL
IV---------------------------------------------------------T
QLGFCCVYFVFLAENFKQVIEAANGTTTNCHDNET-V-ILTPTMDSRLYMLSFLPFLVLL
VFIRNLRVLSIFSLLANISMLVSLIMIYQYIVQKI----PDPRNLPLV------------
ASWKTYPLFFGTAIFAFEGIGMV-L-----PLENKMKDPQKFPLILYLGMGIVT--GLYI
TLGCLGYLQFGADIQGSITLNLPNCWL--YQSVKLLYSIGIFFTYALQFYVPAEIIIPFF
VSRAPEHCELVVDLFVRTVM--VCL----TCILAILVPRLDLVISLVGSVSSSALALIIP
PLLEITTYYSEGMN-PLTIAKDALISILGFVGFVAGTYQALNELIQPSSAPISINS--TS
ASV------------------------

----------------------------------------------HLPTMSKTS-----
-------LLRRD-------DSESNS-----LDDGSKS-VSESSSN-------TSSE-GVH
PAEEA

PF01490 // ENSGT00390000011245_0_Domain_1 (126, 702)

NRLSMMQTLVHLLKCNIGTGLLGLPMAMKNAGILVGPLSLLVIGIITVHCMVI--
LVNCAN--HL-------SHR----------------------------------------
-----------------LQKSFVNYG--EAMMYSLETCPNAWLRTH--SVWGR-------
--------------------------------------------------YTVSFLLIVT
QLGFCSVYFMFMADNLQQIVEEAHVTSNTCQPRK--MLVLTPILDIRFYMLTILPFLVLL
VFIQNLNVLSVFSTLANITTLGSMILIFEYIMQEI----PDPGNLPLM------------
ASWENFLLFFGTAVFTFEGVGMV-L-----PLQNQMKHPQQFSLVLYLGMSLVI--ILFI
CMGSFGYMKFGSKTQATLSNNSGSCRL--YQSVKLMYSIGIFFTYALQFHVPAEIIIPFV
VSQVSESWTLFADLSVRTAL--VCV----TCVSAIIIPRLELIISLMSSVSSSALALIIP
PLLELITFYPEDMS-CVTIAKDIMISIVGLLGCVFGTYQALYELIHPYNHSI-GNSTDVH
A--------------------------

------------------------------------------------------------
-----------------MSTQRLRNEDYHDYSSTDVS-PEDSPSEG-L-NNLSSPGSYQR
FGQS-N

PF01490 // ENSGT00390000011245_0_Domain_1 (127, 699)

STTWFQTLIHLLKGNIGTGLLGLPLAVKNAGIVMGPISLLVIGIVAVHCMGI--
LVKCAH--HF-------CRR----------------------------------------
-----------------LNKSFVDYG--DTVMYGLESSPCSWLRNH--AHWGRRVVDFFL
IV---------------------------------------------------------T
QLGFCCVYFVFLADNFKQVIEAANGTTNNCHNNET-V-ILTPTMDSRLYMLSFLPFLVLL
VFIRNLRALSVFSLLANITMLVSLIMIYQFIVQRI----PDPSHLPLV------------
APWKTYPLFFGTAIFAFEGIGMV-L-----PLENKMKDPRKFPLILYLGMVIVT--IFYI
SLGCLGYLQFGANIQGSITLNLPNCWL--YQSVKLLYSIGIFFTYALQFYVPAEIIIPFF
VSRAPEHCELVVDLFVRTVL--VCL----TCILAILIPRLDLVISLVGSVSSSALALIIP
PLLEVTTFYSEGMS-PLTIFKDALISVLGFVGFVVGTYEALYELIQPSNAPIFINS--TR
AFI------------------------

-----------------------------------------------------MS-----
-------LLGRN-----Y-SKELNS-----LDHGSQP-PSESSS-S-TTS-----E-NVH
PA-GEAG

PF01490 // ENSGT00390000011245_0_Domain_1 (128, 700)

LSMMQTLIHLLKCNIGTGLLGLPLAIKNAGLLVGPVSLLAIGVLTVHCMVI--
LLNCAH--HL-------SQR----------------------------------------
-----------------LHKNFVNYG--EATMYSLETCPNTWLRTH--AVWGRVSLLLPR
LDTMCSGTI---------SAHC---NPHIQGS-SDS--PAQASRVARIYRYTVSFLLIIT
QLGFCSVYFMFMADNLQQMVEEAHVTSNICQPRE--ILVLTPILDIRVYMLTILPCLILL
VFIQNLKVLSIFSTLANITTLGSMALIFEYIMQGI----PYPSDLPLV------------
ANWKTFLLFFGTAIFTFEGVGMV-L-----PLKNQMKHPQQFSFVLYLGMSIVI--VLYI
CLGTLGYMKFGSDTQASITLNLPNCWL--YQSVKLMYSIGIFFTYALQFHVPAEIIIPFA
ISQVSESWALFADLSVRSGL--VCL----TCVSAILIPRLDLVISLIGSVSSSALALIIP
PLLEIVILYSEDMS-YVTFAKDIMISILGLLGCIFGTYQALYELTQPINHSM-ANFTGVY
A--------------------------

------------------------------------------------------------
------------------------------------------------------------
---------

PF01490 // ENSGT00390000011245_0_Domain_1 (130, 686)

WFQTLIHLLKGNIGTGLLGLPLAVKNAGILVGPLSLLLIGIVAVHCMGI--
LVKCAH--HF-------CRR----------------------------------------
-----------------LNKPFVDYG--DTVMYGLESSPSSWLRNH--AHWGRHLVDFFL
IV---------------------------------------------------------T
QLGFCCVYFVFLADNFKQVIEAANGTTNNCHHNET-V-ILTPTMDSRLYMLSFLPFLVLL
VFIRNLRALSIFSLLANISMLVSLVMIYQFIVQXX----XXXXXXXXX------------
XXXXXXXXXX-----XXXXXXXX-XXXXVLPLENKMKDPRKFPLILYGGMAIVT--ALYI
SLGCLGYLQFGAYILS--TLNLPNCWL--YQSVKLLYSGGIFFTYALQFYVPAEIIIPFF
VSRVPEHCELVVDLFIRTLL--VCL----TCILAILIPRLDLVISLVGSVSSSALALIIP
PLLEIATYYSEGMS-PFTIAKDALIS----------------------------------
---------------------------

------------------------------------------------------------
-----------------MSTQRLRNEDYHDYSSTDVS-PEESPSEG-L-NNLSSPGSYQR
FGQS-N

PF01490 // ENSGT00390000011245_0_Domain_1 (127, 699)

STTWFQTLIHLLKGNIGTGLLGLPLAVKNAGIVMGPISLLVIGIVAVHCMGI--
LVKCAH--HF-------CRR----------------------------------------
-----------------LNKSFVDYG--DTVMYGLESSPCSWLRNH--AHWGRHVVDFFL
IV---------------------------------------------------------T
QLGFCCVYFVFLADNFKQVIEAANGTTNNCHNNET-V-ILTPTMDSRLYMLSFLPFLVLL
VFIRNLRALSVFSLLANITMLVSLIMIYQFIVQRI----PDPSHLPLV------------
APWKTYPLFFGTAIFAFEGIGMV-L-----PLENKMKDPRKFPLILYLGMVIVT--ILYI
SLGCLGYLQFGANIQGSITLNLPNCWL--YQSVKLLYSIGIFFTYALQFYVPAEIIIPFF
VSRAPEHCELVVDLFVRTVL--VCL----TCILAILIPRLDLVISLVGSVSSSALALIIP
PLLEVTTFYSEGMS-PLTIFKDALISVLGFVGFVVGTYEALYELIQPSNAPIFINS--TR
AFI------------------------

-----------------------MYRHL----------TFDDRNLFYIHHLYFAV-----
-------LPLSG-----P----------------------------------HHSE-TST
DSPATRS

PF01490 // ENSGT00390000011245_0_Domain_1 (128, 700)

IRMMQTLIHLLKCNIGTGLLGLPLAMKNAGLLVGPFSLLAIGILTVHCMVI--
LLNCAH--HL-------SQR----------------------------------------
-----------------LQKTFVNYG--EAMMYGLETCPNAWLRTH--SVWGR-------
--------------------------------------------------YTVSFLLIIT
QLGFCSVYFMFMADNLQQMVEEAHVTSNTCQPRK--ILVLTPILDIRFYMLIILPFLVLL
VFIQNLRVLSIFSTLANITTLGSMALIFEYIVQGI----PDPRNLPLM------------
ASWKTFLLFFGTAIFTFEGVGIV-L-----SLKNQMKHPQQFSFVLYLGMSLVI--VLYI
CLGTLGYMKFGSNTQASITLNLPNCWL--YQSVKLMYSIGIFFTYALQFHVPAEIIIPIV
ISQVSESWALFADLSVRTAL--VCL----TCVSAILIPRLDLVISLVGSVSSSALALIIP
PLLELITFYPEDMS-CVTIAKDIMISMLGLLGCVFGTYQALYELIQPVSHSI-ANSTGVY
A--------------------------

--------------------------------------------------MVKAS-----
-------LLRKD------GNCEWNF-----FSVAKNS-SQSSSSS--SGSQRTVSP-RKD
PQGEVNGLQ

PF01490 // ENSGT00390000011245_0_Domain_1 (130, 700)

FMQIFIHLLKSNIGTRFLGLPLAVKNAGLLVGPVSLLAIGVLTVHCMDI--
LLKCAS--HL-------TQR----------------------------------------
-----------------LQRSLVNYE--ETMMYSLETCPNPWLRTH--SAWGRY------
---------------------------------------------------IVNFLLIVT
QLGFCSVYFMFMADNLQQIVEEAHFTSNICQPRE--SLVKIPVLDAPFYMLTILPFLILL
VLVQNPQVLSVFFTLATITTLGSLAVIFKYLIQ-I----PWHSSLPLV------------
ASWKTFLLFFGTTIFTFEGVGMV-L-----PLKSQMKSPQQFPAVLYLSMSFVI--FLYI
CLGTLGYMKFGSDTQPSITLNLPNCWL--YQSVKLMYSVGIFFTYALQFHVPAEIIIPYV
ISRVSEKWVLFVNLTVRTAL--VCL----TCFSAVFIPRLDLVISLVVSVSSSTLALIIP
PLLEIATFYSENMS-CVTIAKDVMISILGLLGCVFGTYQALYEMTQQAHLSM-ANSTKGY
T--------------------------

--------------------------------------------------MSVEKSTKDP
QGTVTLQLELKSPPESVK---ELQKKDSN-FLDG--S-PSESP-----------------
GLEKA

PF01490 // ENSGT00390000011245_0_Domain_1 (126, 702)

KGITGFQALIHLVKSNVGTGILGLPLAVRNAGILLGPLSLLVMGIVATHCMHI--
LVQCAQ--RF-------CRR----------------------------------------
-----------------FNKPFMDYG--DTVMHGLEASPSTWLQNH--AHWGRHLVSFFL
IV---------------------------------------------------------T
QLGFCSVYIVFLADNLKQVVEAINATTNKCHYNET-M-ILTPTMDSRLYMLTFLPGLVLL
VFVRSLRILTIFSTLANLSMLVSLVIITQYIAQEI----PDPRQLPLI------------
ASWKTYPLFFGTAIISFESIGMV-L-----PLENKMKNARRFPAILSLGMSIVT--IMYI
GMGALGYLRFGDNIRASITLNLPNCWL--YQSVKILYIVCILCTYPLQFYVPAEIVIPWA
VSRVSKRWELPLDLSIRVAM--VCL----TCVLAILVPRLDLVLALVGSVSSSVLALIIP
PLLEIITFYSEGMN-PLTITKDVLISVLGFVGFVAGTYKALDDLIETEDSHTFSNST---
VFTQ-----------------------

------------------------------------------------------------
-----------------MSRQYLRSEDYQDYSSTDAS-PEESPADR-P-GTFSSSGSYQR
FGES-

PF01490 // ENSGT00390000011245_0_Domain_1 (126, 702)

NSTTWFQTLVHLLKGNIGTGLLGLPLAVKNAGILMGPLSLLVIGIVAVHCMGI--
LVKCAH--HF-------CRR----------------------------------------
-----------------MNKPFVDYG--DTVMYGLESCPSSWLRDH--SHWGRHIVDFFL
IV---------------------------------------------------------T
QLGFCCVYFVFLADNFKQVIEAANVTTNNCHTNET-V-VLTPTMDSRLYMLTFLPFLVLL
VFFRNLRVLSIFSLLANITMLVSLVMIYQFIVQXX----XXXXXXXXX------------
XXXXXXXXXX-----XXXXXXXX-XXXXVLPLENKMKDPQRFPLILYLGMAIIT--VLYI
SLGCLGYLQFGANIQGSITLNLPNCWL--YQSVKLLYSVGIFFTYALQFYVPAEIIVPFF
VSRVAEGYKLAVDLFVRTVL--VCI----TCVLAILIPRLDLVISLVGSVSSSALALIIP
PLLEISTFYSEGLG-PLTITKDALISILGFLGFVVGTYQALEELIQPALTPIHVSA--TS
AFM------------------------

--------------------------------------------------MGNVP-----
-------LLREV------GKCQRNM-----FGRSTAS-SKGSSNSRS---SSSTSP-KKG
PRREADALMF

PF01490 // ENSGT00390000011245_0_Domain_1 (131, 700)

IQIFIHLLKSNIGTGFLGLPLAVKNAGLLVGPVSLLAIGALTVHCMDI--
LLNCAC--HL-------TQR----------------------------------------
-----------------LQRSFVNYE--ETTMYSLETCPSPWLRTH--SVWGRY------
---------------------------------------------------VVSFLLIVT
QLGFCSVYFMFLADNLQQIMEEAHFTSNVCQPRQ--SLVMTSILDTRFYMLTILPFLILL
VLIQNPQVLSIFSTLATITTLSSLALIFEYLIQ-T----PHHSNLPLV------------
ANWKTFLLFFGTAIFTFEGVGMV-L-----PLKSQMKSPQQFPAVLYLGMSFVI--FLYI
CLGTLGYMKFGTDTQASITLNLPICWL--YQSVKLMYSVGIFFTYALQFHVPAEIIVPYV
VSRVSENWALFVDLTVRTAL--VCL----TCFSAVLIPRLDLVISLVGSVSSSALAIIIP
PLLEIATFYSENIS-CATIVKDIMISILGLLGCVLGTYQALYEMTQQTHFYM-ANSTRVH
I--------------------------

--------------------------------------------------MSVTK---ST
EGAVAVKLDLMSPPESAK---KLENKDST-FLDE--S-PSESP-----------------
GLKKTK

PF01490 // ENSGT00390000011245_0_Domain_1 (127, 700)

GITVIQALIHLVKGNMGTGILGLSLAVKNAGILMGPLSLLVMGLIACHCMHI--
LVRCAQ--RF-------CKR----------------------------------------
-----------------LNKPFMDYG--DTVMHGLEASPSAWLQNH--AHWGR-------
------------------------------------------------------------
-------YIVFLADNLKQVVEAVNSTTNNCHSNET-V-ILIPTMDSRLYMLSFLPFLVLL
VLIRNLRILTIFSMLANISMLVSLVIIAQYITQEI----PDPSRLPLV------------
ASWKTYPLFFGTAIFSFESIGVV-L-----PLENKMKNARHFPAILSLGMSIVT--SLYI
SIGTLGYLRFGDDIKASISLNLPNCWL--YQSVKLLYIAGILCTYALQFYVPAEIIIPFA
ISRVSTHWALPLDLSIRLAM--VCL----TCLLAVLIPRLDLVISLVGSVSSSALALIIP
PLLEVSTFYSEGMS-PLTIFKDALISILGFVGFVVGTYQALDELLKSGDSPLFSNST---
TFLR-----------------------

--------------------------------------------------MSETSSAEGP
QEAGVFKLDIISPGNDQK-----LQEDPG-FSDG--S-STEPP-----------------
GQGKP

PF01490 // ENSGT00390000011245_0_Domain_1 (126, 702)

KGITGFQALVHLVKGNVGTGLLGLPLAMKNSGLLMGSLSLLVMGYIALHCMHI--
LVRCAQ--RF-------CKR----------------------------------------
-----------------LNKPFLDYG--ETVMHGMEAGPSAWLKKH--ALWGRHLVVFFL
IV---------------------------------------------------------T
QLGFCCVYIVFLADNLKQIVEAINSTTTNCHVDGP-M-LLTPTMDSRLYMLAFLPFLVLL
VFFRNLRVLTVLSLFANISMLVSLVILTQYIVQDI----PDPSQLPLV------------
SSWKTYPLFFGTAVFSYESIGVV-L-----PLENKMKDTRHFPVILSLGMTIVI--LLYI
LVATLGYLRFGDEIMASITLNLPNCWL--YQSVKILYVLGILCSYTLQFYIPAETIVPWA
VSKVPQRWALLTDLGTRLVM--VCL----TGVLAILIPRLDLVLALVGSVSSSALAFIIP
PLLEITTFYSDGLN-PFIIVKDVLISILGFLGFVVGTYQALDELMRPQHPLTFSNST---
TFLH-----------------------

--------------------------------------------------MSVTK---ST
EGAVAVKLDLMSPPESAK---KLENKDST-FLDE--S-PSESP-----------------
GLKKTK

PF01490 // ENSGT00390000011245_0_Domain_1 (127, 700)

GITVIQALIHLVKGNMGTGILGLSLAVKNAGILMGPLSLLVMGLIACHCMHI--
LVRCAQ--RF-------CKR----------------------------------------
-----------------LNKPFMDYG--DTVMHGLEASPSAWLQNH--AHWGRHIVSFFL
IV---------------------------------------------------------T
QLGFCCVYIVFLADNLKQVVEAVNSTTNNCHSNET-V-ILTPTMDSRLYMLSFLPFLVLL
VLIRNLRILTIFSMLANISMLVSLVIITQYITQEI----PDPSRLPLV------------
ASWKTYPLFFGTAIFSFESIGVV-L-----PLENKMKNARHFPAILSLGMSIVT--SLYI
SIATLGYLRFGDDIKASISLNLPNCWL--YQSVKLLYIAGILCTYALQFYVPAEIIIPFA
ISRVSTRWALPLDLSIRLAM--VCL----TCLLAVLIPRLDLVISLVGSVSSSALALIIP
PLLEVSTFYSEGMS-PLTIFKDALISILGFVGFVVGTYQALDELLKSGDSPLFSNST---
TFLR-----------------------

------------------------------------------------------------
------------------------------------------------------------
---------VKQTLVHFLKCKSGTGLLGLPA-MKNACLXXXXXXXXXXXXXXXXXXXX--
XXXXXXXXXX-------XXX----------------------------------------
-----------------XXXXXXXXX--XXXXXXXXXXXXXXXXXX--XXXXXX------
-----XXXX--------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXYTVSFLLIIT
QLGFCSVYFVFMAENWQQTAEETHVTTSRKV-------PVLNILDICFYTLIFMLFLILW
VFVQNLMVLSVCSTLANITTLESMGLIFKYVVQET----PDASHLLLV------------
TRLKTLL-FFG-STFTFEGIVV------------------HLEFVLHLGMCLFI--GLYF
RLETXXXXXXXXXXXXXXXXXXXXXXX--XXXXX---------------------XXXXX
XXXXXXXXXXXXXXXXXXXX--XXX----XXVS

PF01490 // ENSGT00390000011245_0_Domain_2 (634, 663)

AILIPHLDLIISQVGSMSSSPLTLIIP
PFLKT-LLHPEDMN-CVTISKNALYELTQLINYLMATV--------------------VY
TQ-------------------------

-----------------------------------------------------MS-----
-------LLGRD-----Y-NSELNS-----LDNGPQS-PSESSS-S-ITS-----E-NVH
PA-GEAGLSMMQTLIHLLKCNIGTGLLGLPLAIKNAGLL---------------------
------------------------------------------------------------
-----------------LQKTFVNYG--EATMYGLETCPNTWLRAH--AVWGRWNLALSP
-RLECSGNI---------SAHC---NPHLQGS-SNS--PAQASRVAG

PF01490 // ENSGT00390000011245_0_Domain_1 (348, 700)

IYRYTVSFLLVIT
QLGFCSVYFMFMADNLQQMVEEAHVTSNICQPRE--ILTLTPILDIRFYMLIILPFLILL
VFIQNLKVLSVFSTLANITTLGSMALIFEYIMQGI----PYPSNLPLM------------
ANWKTFLLFFGTAIFTFEGVGMV-L-----PLKNQMKHPQQFSFVLYLGMSIVI--ILYI
LLGTLGYMKFGSDTQASITLNLPNCWL--YQSVKLLYSIGIFFTYALQFHVPAEIVIPFA
ISQVSESWALFVDLSVRSAL--VCL----TCVSAILIPRLDLVISLVGSVSSSALALIIP
ALLEIVIFYSEDMS-CVTIAKDIMISIVGLLGCIFGTYQALYELPQPISHSM-ANSTGVH
A--------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

PF01490 // ENSGT00390000011245_0_Domain_1 (351, 702)

YTVSFLLIIT
QLGFCSVYFMFMADNLQQIVEEAHVTSNTCHPRK--IMVLTPILDIRLYMLTILPFLILL
VFIQNLKVLSVFSTLANITTLGSMILIFEYIVQGI----PDPRNLPLM------------
AGWKTFLLFFGTAIFTFEGVGMV-L-----SLKNQMKHPQQFSFVLYLGMSIVI--ILYV
CLGTLGYMKFGSGTQASVTLNLPNCWL--YQSVKLMYSTGIFFTYALQFHVPAEIIIPFP
ISKVSESWALFADLSGRTAL--VCL----TCVSAIIIPRLDMIISLVGSVSSSALALIIP
PFLEILTFYPEDMS-CITIAKDIMISIMGLLGCIFGTYQAIYELNQPINHSI-ANSTGV-
------------YA-------------

--------------------------------------------------MSVTK---ST
EGAVAVKLDLMSPPESAK---KLENKDST-FSDE--S-PSESP-----------------
GLKKTK

PF01490 // ENSGT00390000011245_0_Domain_1 (127, 597)

GITVIQALIHLVKGNMGTGILGLSLAVKNAGILMGPLSLLVMGLIACHCMHI--
LVRCAQ--RF-------CKR----------------------------------------
-----------------LNKPFMDYG--DTVMHGLEASPSAWLQNH--AHWGV-------
------------------------------------------------------------
-------------------VEAVNSTTNNCHSNET-V-ILIPTMDSRLYMLSFLPFLVLL
VLIRNLRILTIFSMLANISMLVSLVIIAQYITQEI----PDPSRLPLV------------
ASWKTYPLFFGTAIFSFESIGVV-L-----PLENKMKNARHFPAILSLGMSIVT--SLYI
SIGTLGYLRFGDDIKASISLNLPNCWL--YQSVKLLYIAGILCTYALQFYVPAEIIIPFA
ISRVSTRWALPLDLSIRLAM--VCL----TCE----------------------------
------------------------------------------------------------
---------------------------

-MATLNKD------------------------------PIGD-L-ELKN-----------
-K-----ASVAFTVTSPDSTWKLQNKEYHNYGSGDGS----SPESG-N-NGL-DPGS---
YRKG-K

PF01490 // ENSGT00390000011245_0_Domain_1 (127, 701)

GITVFQTLIHLLKGNIGTGLLGLPLAVKNAGLLMGPLSLLVMGIVAVHCMGI--
LVKCAN--HF-------CQR----------------------------------------
-----------------LQKPFLDYG--DAVMYGLKTSPCSWLQKH--ALWGRHIVGFFL
IL---------------------------------------------------------T
QLGFCCVYFVFLADNLKQVIEAANTTTLNCYSNET-V-TLTPTMDSRLYMLSFLPFVVLL
VFVRNLRLLSIFSMLANISMLVSLVVIYQYIVQDI----PDPQNLPLI------------
SSWKTYPLFFGTAIFAFESIGVV-L-----PLENKMKKSEQFPFILYLGMTIIT--LLYI
SLGCLGYLKFGDDIQASITLNLPNCWL--YQSVKLLYSLGIFFTYALQFYVPAEIIIPFA
VSHVPKSWNLAVDLFIRTAL--VSV----TCVLAILVPRLDLVIALVGSMSSSALALIIP
PLLEIITFYSEGMS-PITIIKDILISVLGFIGFVVGTYQSIYELTQPPVSHTFANI--TS
SFVQ-----------------------

------------------------------------------------------------
--------------------RRLRNEDYNDYSSTEIS-PSESPSDG-L-SNFSSPGSYQR
FGEA-D

PF01490 // ENSGT00390000011245_0_Domain_1 (127, 271)

GTTWFQTLIHLLKGNIGTGLLGLPLAVKNAGLLMGPVSLLVMGIVAVHCMGI--
LVKCAH--HF-------CHR----------------------------------------
-----------------LQRPFVDYG--DAVMFGLEA-PNSWLRTH--SMWGRKWNPCLH
PGLACSAEVTDH------------CLPHHNQG-----------DVQFINKINRVTKIYTV
ERTSTVAQIVFLADNIKQVVEAANGTTNNCHNNET-V-VLTPSMDSRLYMLAFLPFLVLL
VFIRNLKVLSIFSMLANVSMLGSLIMIYQYIVQGI----PDPSILPLV------------
ASWKTYPLFFGTAIFAFEGIGVV-L-----PLENKMKNPQRFPVILYVGMCIVT--ILYI
SLGVLGYLRFGAAIQASITLNLPNCWL--YQSVKLLYSVGIFFTYALQFYVPAEIIIPFT
VSRVPERWALATDLAVRTGI--VCV----TCVLAILIPRLDLVIALVGSVSSSALALIIP
PLLEITTYYSEGIS-PATILKDVLISVLGFVGFVVGTYQALYELIQPSAPSTLTNS--TS
AFV------------------------

--------------------------------------------------MGKMS-----
-------LLRKD------DNCERNL-----FSVCKAT-SSSSSSS--SSNNSLVSP-QKD
PPEEADALLF

PF01490 // ENSGT00390000011245_0_Domain_1 (131, 700)

MQIFIHLLKSNIGTGFLGLPLAVKNAGLLVGPISLLAIGVLTVHCMDI--
LLNCAS--HL-------TQR----------------------------------------
-----------------LQKSFVSYE--ETTMYSLETCPNPWLRTH--SVWGRY------
---------------------------------------------------IVSFLLIIT
QLGFCSVYFMFMADNLQQIVEEAHFTSNVCQPRK--SLVLTPVLDARFYMLTILPFLILL
VLVQNPQVLSIFSTLATITTLGSLALIFEYLIQ-T----PRHSSLPLV------------
ASWKTFLLFFGTAIFTFEGVGMV-L-----PLKSQMKSPQQFPAVLYLGMSFVI--FLYI
CLGTLGYMKFGSDTQASITLNLPNCWL--YQSVKLMYSVGIFFTYALQFHVPAEIIIPYV
ISRVSENWALFVDLTVRTAL--VCL----TCFSAVLIPRLDLVISLVGSVSSSALALIIP
PLLEITTFYSEKMS-CVTIAKDIMISILGLLGCVFGTYQALYEMTQQAHFSM-ANWTRVY
T--------------------------

------------------------------------------------------------
-----------------MSTQRLRNEDYHDYSSTDVS-PEESPSEG-L-SNPSSPGSYQR
FGES-NSTTWFQTLIHLLKGNIGTGLLGLPLAVKNAGILMGPLSLLVIGIVAVHCMGI--
LVKCAH--HF-------CHR----------------------------------------
-----------------LNKSFVDYG--DTVMYGLESSPCSCLRNH--AHWGRHIVDFFL
IV---------------------------------------------------------T
QLGFCCVYFVFLADNFKQVIEAANGTTNNCHSNET-V-IANPTMDSRLYMLSFLPFLVLL
VFVRNLRALSIFSLLANISMLVSLVMI

PF01490 // ENSGT00390000011245_0_Domain_1 (448, 700)

FQFIVQ---------------------------
----------------------V-L-----PLENKMKDPQKFPLILYVGMVIVT--ALYI
SLGCLGYLQFGSSIKGSVTLNLPNCWL--YQSVKLLYSIGIFFTYALQFYVPAEIIIPFF
VSRVPEHCELVVDLFVRTVL--VCL----TCILAILVPRLDLVISLVGSVSSSALALIIP
PLLEITTYYSEGMS-PLTIAKDALISILGFVGFVVGTYQALNELIQPSNAPILVNS--TR
AFV------------------------

------------------------------------------------------------
-----------------MSTQRLRNEDYQDYSSTDVS-PEESPSES-L-GNLP-PGAYQR
LGES-N

PF01490 // ENSGT00390000011245_0_Domain_1 (127, 699)

STTWFQTLIHLLKGNIGTGLLGLPLAVKNAGILLGPLSLLVIGIAAVHCMGL--
LVKC-AR-HF-------CCR----------------------------------------
-----------------LNKPFVDYG--DTVMYGLESSPSAWLRNH--AHWGRRVVDFFL
IV---------------------------------------------------------T
QLGFCCVYFVFLADNFKQVIEAANGTTNNCHNNET-A-ILMPTMDSRLYMLAFLPFLVLL
VFIRNLRALSVFSLLANMSMLVSLVLIYQFIVQGI----PNPSRLPLV------------
ASWKTYPLFFGTAIFAFEGIGMV-L-----PLENKMKDPQKFSFILYLGMAIVT--ILYI
SLGSLGYLQFGASIQGSITLNLPNCWL--YQSVKLLYSIGIFFTYGLQFYVPAEIIVPFF
VSRVPEPCKLLVDLAVRTAM--VCL----TCVLAVLIPRLDLVISLVGSVSSSALALIIP
PLLEVTTYSSEGLS-PLTLAKDALISILGFVGFVVGTYEALSELIQPGAAPISTNS--SS
AFAYRAGYIL-----------------

----MGDPGQITPCLGATVLPRKMWLELHNLCLSLISSTLPVEA-EAVRVMPVTKSAEGP
QGADALKLDVIPSPTSAK---HLQNKDSS-CVDG--S-SSESP-----------------
GLEKTKG

PF01490 // ENSGT00390000011245_0_Domain_1 (128, 700)

ITEFQTLIHLLKGNMGTGILGLPLAVKNAGILMGPLSLLVMGFIACHCMHI--
LVRCAQ--HF-------CHR----------------------------------------
-----------------LNKPFMDYG--DTVMHGLEASPSAWLRDH--AQWGRHIVSFFL
IV---------------------------------------------------------T
QLGFCCVYIVFLADNLKQVVEAVNSTTNNCHYNET-V-VLTPTVDSRLYMLAFLPFLVLL
VFIRNLRVLTVFSLLANISMLVSLVILTQFIAQEI----PDPSRLPLV------------
ASWKTYPLFFGTAIFSFESIGVV-L-----PLENKMKDARHFPAMLSLGMSIIT--AMYT
GVGALGYLRFGDDIKASITLNLPNCWL--YQSVKLLYIVGILCTYALQFFVPAEIIIPFA
VSQVSKRWALPLDLSIRLAM--VFL----TGILAILVPRLDLVLSLVGSVSSSALALIIP
PLLEITTYYSEGMS-PLAIIKDALISIMGFVGFVAGTYQALDELLASGESLTFSNST---
FIQ------------------------

------------------------------------------------------------
-----------------MSTQRLRNEDYADYSSTDVS-PDESPSEG-L-NNFSSSGSYQR
FGES-

PF01490 // ENSGT00390000011245_0_Domain_1 (126, 702)

SSTTWFQTLIHLLKGNIGTGLLGLPLAVKNAGILMGPLSLLVIGIVAVHCMGI--
LVKCAH--HF-------CHR----------------------------------------
-----------------LNKPFVDYG--ETVMYGLESSPISWLRNH--AHWGRHTVDFFL
IV---------------------------------------------------------T
QLGFCCVYFVFLADNFKQVIEAANGTTNNCHNNET-V-ILMPTMDSRLYMLTFLPFLVLL
VFVRNLRVLSIFSLLANITMLVSLFMIYQFIVQGI----PDPHRLPLV------------
APWKTYPLFFGTAIFAFEGIGMV-L-----PLENKMKDPRKFPIILYVGMGIVT--TLYI
SLGCLGYLQFGADIQGSITLNLPNCWL--YQSVKLLYSIGIFFTYAIQFFVPAEIIIPFF
VSRVPEHWELAVDLLVRTML--VCL----TCILAILIPRLDLVISLVGSVSSSALALIIP
PLLEITTYYSEGLS-PLTIAKDALISILGFVGFVVGTYEALYELIQPSPAPSFINS--TS
AFA------------------------

-------------------------RH------------------HPPTMLKISL-----
-------LARDN-----T-SKP-KS-----LDDGSKS-LSESSSS-------ITSE-RIH
PAEEANG

PF01490 // ENSGT00390000011245_0_Domain_1 (128, 700)

LSMMQTLIHLLKCNIGTGLLGLPLAMKNAGLLVGPFSLLAIGILTVHCMVI--
LLNCAH--HL-------SQR----------------------------------------
-----------------LQKTFVNYG--EAMMYSLETCPNAWLRTH--SVWGR-------
--------------------------------------------------YTVSFLLITT
QLGFCSVYFMFMADNLQQMVEEVHVTSKTCEPRK--ILVLTPNVDIRFYMLTILPFLILL
VFIQNLRVLSIFSTLANITTLGSMALIFQYIMQEI----PDPRNLPLM------------
ASWKTFLLFFGTAIFTFEGVGMV-L-----PLKNQMKHPQQFSFVLYWGMSLVI--VLYI
CLGTLGYMKFGSNTQASITLNLPNCWL--YQSVKLMYSIGIFFTYALQFHVPAEIIIPVI
ISQVSETWALFADLSVRTAL--VCL----TCVSAILIPRLDLVISLVGSVSSSALALIIP
PFLELITFYPEDMN-CITIVKDIMISILGLLGCVFGTYQALYELTQPINHSV-ANSTGVY
A--------------------------

--------------------------------------------------MAVAKNVRDL
QGTVSLNLDLRSSPQSTK---NLQNKDSG-FLDV--N-SSEST-----------------
DLDKTKG

PF01490 // ENSGT00390000011245_0_Domain_1 (128, 700)

ITGFQTLVHVLKGNMGTGILGLPLAVKNAGILMGPLSLLVMGFIACHCMHI--
LVRCAR--RF-------CHR----------------------------------------
-----------------------------------------------------HIVSFFL
II---------------------------------------------------------T
QLGFCCVYIVFLAENLKQVVEAVNSTTNNCYNNET-V-IPMPTMDSRLYMLSFLPVLVLL
VFIRNLQILTIFSMLANISMLASLIIIAQYIAQGI----PDPSRLPLV------------
ASWKTYPLFFGTAIFSFESIGVV-L-----PLENKMKDASRFPAILSLGLSIVT--ALYT
SIGTLGYLRFGDDIKASITLNLPNCWL--YQSVKLLYIIGILCTYALQFYVPAEIIIPFT
VSRVSKRWSLLVDLSMRFAL--VCL----TCILAVLVPRLDLVLSLVGSVSSSALALIIP
PLLEITTYYSEGMN-PLTIAKDALISILGFVGFVVGTYQALDELIKPEDSLPFSNST---
IFML-----------------------

------------------------------------------------------------
-----------------MSTQRLRNEDYHDYSSTDVS-PEESPSEG-L-GNFS-PGSYQR
LGEN-NSTTWFQTLIHLLKGNIGTGLLGLPLAVRNAGILLGPLSLLVIGIVAVHCMGI--
LVKCAR--HL-------CLR----------------------------------------
-----------------NSKPFLDYG--DTVMYGLECSPSSWIRSH--SHWGRHIVDFFL
IV---------------------------------------------------------T
QLGFCCVYFVFLADNFKQVIEAAXXXXXXXXXXXX-X-XXXXXXX---------------
-------XXXXXXXXXXXXXXXXXXTIYQFILQRI----PDPHHLPLV------------
ASW

PF01490 // ENSGT00390000011245_0_Domain_1 (484, 699)

KTYPLFFGTAVFAFEGIGVV-L-----PLENKMKNSQKFPCILYLGMTIVT--VLYI
SLGSLGYLQFGAAIKASITLNLPNCWL--YQTVKLLYSIGIFFTYALQFYVAAEIMVPVI
VSRVPEHCTLLVDLCVRTAM--VCI----TCVLAILIPRLDLVLSLVGSMSSSALALIIP
PLLEVTTFYEEGLS-PLTIAKDVLISIFGFVGFVVGTYESLCELIFPSHSNTSTNS--TS
AFI------------------------

-----------------------------------------------------MS-----
-------LLGRD-----Y-NSELNS-----LDNGSQS-PSESSS-S-ITS-----E-NVH
PA-GEAG

PF01490 // ENSGT00390000011245_0_Domain_1 (128, 700)

LSMMQTLIHLLKCNIGTGLLGLPLAIKNAGLLVGPVSLLAIGVLTVHCMVI--
LLNCAQ--HL-------SQR----------------------------------------
-----------------LQKTFVNYG--EATMYSLETCPNTWLRTH--AVWGRY------
---------------------------------------------------TVSFLLVIT
QLGFCSVYFMFMADNLQQMVEEAHVTSNICQPRE--ILTLTPILDIRFYMLIILPFLILL
VFIQNLKVLSVFSTLANITTLGSMALIFEYIMQGI----PYPSNLPLM------------
ANWKTFLLFFGTAIFTFEGVGMV-L-----PLKNQMKHPQQFSFVLYLGMSIVI--ILYI
LLGTLGYMKFGSDTQASITLNLPNCWL--YQSVKLMYSIGIFFTYALQFHVPAEIIIPFA
ISQVSESWALFVDLSVRSAL--VCL----TCVSAILIPRLDLVISLVGSVSSSALALIIP
ALLEIIIFYSEDMS-CVTIAKDIMISILGLLGCIFGTYQALYELTQPISHSM-ANSTGVY
A--------------------------

------------------------------------------------------------
-----------------MSTQRLRNEDYHDYSSTDVS-PEESPSEG-L-GNFS-PGSYQR
LGEN-S

PF01490 // ENSGT00390000011245_0_Domain_1 (127, 700)

STTWFQTLVHLLKGNIGTGLLGLPLAVKNAGLLLGPLSLLVIGIVAVHCMSI--
LVKCAH--HL-------CRR----------------------------------------
-----------------LNKPFLDYG--DTVMHGLECSPSAWVRSH--SHWGRHIVDFFL
IV---------------------------------------------------------T
QLGFCCVYFVFLADNFKQVIEAANGTTTNCHNNET-V-VLTPTMDSRLYMLAFLPFLVLL
TFIRNLRVLSIFSLLANISMLVSLVTIYQFTIQRI----PDPSHLPLV------------
APWKTYPLFFGTAIFAFEGIGMV-L-----PLENKMKDSQKFPFILYLGMTIIT--ALYI
SLGTLGYLQFGDSIKGSITLNLPNCWL--YQSVKLLYSIGIFFTYALQFYVAAEIIIPVV
TSRVPEHYQTMVDFSVRTAL--VCI----TCVLAILIPRLDLVISLVGSLSSSALALIIP
PLLEVTTYYGEGLS-PLIIIKDALISILGFVGFVVGTYQSLFELIQPSQVDISTNL--TS
AFI------------------------

------------------------------------------------------------
-----------------MSTQRLRNEDYHDYSSTDVS-PEESPSEG-L-NNLSSPGSYQR
FGQS-N

PF01490 // ENSGT00390000011245_0_Domain_1 (127, 699)

STTWFQTLIHLLKGNIGTGLLGLPLAVKNAGIVMGPISLLIIGIVAVHCMGI--
LVKCAH--HF-------CRR----------------------------------------
-----------------LNKSFVDYG--DTVMYGLESSPCSWLRNH--AHWGRRVVDFFL
IV---------------------------------------------------------T
QLGFCCVYFVFLADNFKQVIEAANGTTNNCHNNET-V-ILTPTMDSRLYMLSFLPFLVLL
VFIRNLRALSIFSLLANITMLVSLVMIYQFIVQRI----PDPSHLPLV------------
APWKTYPLFFGTAIFSFEGIGMV-L-----PLENKMKDPRKFPLILYLGMVIVT--ILYI
SLGCLGYLQFGANIQGSITLNLPNCWL--YQSVKLLYSIGIFFTYALQFYVPAEIIIPFF
VSRAPGHCELVVDLFVRTVL--VCL----TCILAILIPRLDLVISLVGSVSSSALALIIP
PLLEVTTFYSEGMS-PLTIFKDALISILGFVGFVVGTYEALYELIQPSNAPIFINS--TR
AFI------------------------

-----------------------------------------------------MS-----
-------LFGKD-----Y-NNESKS-----LDNGSKS-LLESSSS-------ITSE-SVH
AAEEA

PF01490 // ENSGT00390000011245_0_Domain_1 (126, 702)

SGISIVQTLIHLLRCNIGTRLLGLPLAMKNAGLLVGPS-LLAIGXXXXXXXXX--
XXXXXX--XX-------XXX----------------------------------------
-----------------XXXXXXX-------------------XXX----XX--------
------------------------------XXXXXXXXXXXXXXXXXXXXYTVSFLLIIT
QLGFCSIYFIFMADNLQQMVEEAHLTSNTCQPRK--ILVPTPILDIRFYMLLLLPLLILL
VFIQNLRVLSIFSTLANIATLGSMALIFEYIVQGI----PDPRNLPLM------------
ASWKTFLVFFSTAIFTFEGVGMV-L-----SLKNQMKHPQEFSFVLYLGMSLII--ILYI
CLGTLGYMKFGLNTQASITLNLPNCXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXX--XXX----XXVSAILIPRLDLVISLVGSVSSSALALIIP
PLLELITFYPEDMS-CVTIAKDIMISILGLLGCVFGTYQALYELIQPINHSI-ANSTG--
---------------------------

------------------------------------------------------------
------------------------------------------------------------
---------MMQTLIHLLKCNIGTGLLGLPLAIKNAGLLVGPVSLLAIGVLTVHCMVI--
LLNCAH--HL-------SQR----------------------------------------
-----------------LHKTFVNYG--EATMYSLETCPNTWLRTH--AVWGRVSLLLPR
--LECNGLI---------STHR---NLLLLEI-ILMCVFSFCLPLPFLP

PF01490 // ENSGT00390000011245_0_Domain_1 (350, 700)

RYTVSFLLIIT
QLGFCSVYFMFMAENLQQMVEEAHVTSNICQPRE--ILVLTPILDIRVYMLTILPFLILL
VFIQNLKVLSIFSTLANITTLGSMALIFEYIMQGI----PYPIDLPLM------------
ANWKTFLLFFGTAIFTFEGVGMV-L-----PLKNQMKHPQQFSFVLYLGMSIVI--ILYM
CLGTLGYMKFGSDTQASITLNLPNCWL--YQSVKLMYSIGIFFTYALQFYIPAEIIIPFA
ISQVSESWTLFVDLSVRSAL--VCL----TCVSAILIPRLELVISLVGSVSSSALALIIP
PLLEIVILYSEDMS-YVTIAKDIMISILGLLGCIFGTYQALYELTQPINHSM-ANSTGIH
A--------------------------

------------------------------------------------------------
-----------------------------------------MH--------ISTLT-LLC
FPLSFSLLRGF

PF01490 // ENSGT00390000011245_0_Domain_1 (132, 701)

QALTHLFKANIGTGLLGLPLAMKNAGIIVGPLSLLMLGVMIVHCMGI--
LVKCAH--HF-------CHR----------------------------------------
-----------------LQKPFVDYG--DTVMYGLEASPFLWLRSH--SLWAR-------
--------------------------------------------------HLVRSLLIIT
QLGFCSVYFLFLADNFKQVAETASI-SNRCLQNETTM-GMLPSLNLHLYMLTFLPFVILL
VFFHNLLMLTIFSTVGNIAILGSVALIFSYITQDI----PNPKNLPWS------------
ANWQTYSLFFGTAIFSLEGIGVI-L-----PLENQMKYPGHYTLILYMVMPIII--ILYV
SLGTLGYMKFGENIQASITLNLPNCWL--YQSVKMLYSIGIFFTYALQFYIPAEIIIPHV
ISWVPEQWELLVDLSVRGIM--VCM----TYIFAMMIPQMELIIALLGSASCCVLALIIP
PLLEICTYYMDGLS-SFTVIKDVFISTMGILGCIMGTYQAFYEIIDQTFFSSSQNSTRVF
V--------------------------

------------------------------------------------------------
-----------------MSTQRLRNEDYHDYSSTDVS-PEESPSEG-L-NNLSSPGSYQR
FGQS-N

PF01490 // ENSGT00390000011245_0_Domain_1 (127, 699)

STTWFQTLIHLLKGNIGTGLLGLPLAVKNAGIVMGPISLLVIGIVAVHCMGI--
LVKCAH--HF-------CRR----------------------------------------
-----------------LNKSFVDYG--DTVMYGLESSPCSWLRNH--AHWGRHIVDFFL
IV---------------------------------------------------------T
QLGFCCVYFVFLADNFKQVIEAANGTTNNCHNNET-V-ILTPTMDSRLYMLSFLPFLVLL
VFIRNLRALSVFSLLANITMLVSLIMIYQFIVQRI----PDPSHLPLV------------
APWKTYPLFFGTAIFAFEGIGMV-L-----PLENKMKDPRKFPLILYLGMVIVT--ILYI
SLGCLGYLQFGANIQGSITLNLPNCWL--YQSVKLLYSIGIFFTYALQFYVPAEIIIPFF
VSRAPEHCELVVDLFVRTVL--VCL----TCILAILIPRLDLVISLVGSVSSSALALIIP
PLLEVTTFYSEGMS-PLTIFKDALISVLGFVGFVVGTYEALYELIQPSNAPIFINS--TR
AFI------------------------

--------------------------------------------------MPVTKNAEGP
QEAATLKLDLMPSPKSTK---KLQNKDSG-FLDG--S-SSESS-----------------
GLEKTK

PF01490 // ENSGT00390000011245_0_Domain_1 (127, 700)

GITAFQTLVHLVKGNMGTGVLGLPLAVKNAGILVGPLSLLVMGFVACHCMHI--
LVRCAQ--HF-------CRR----------------------------------------
-----------------LNKPFMDYG--ETVMLGLEASPSVWLRSR--AHWGRHIVSVFL
VV---------------------------------------------------------T
QLGFCCVYIVFLADNLKQVIEAVNGTTHNCHNNKT-M-TLTPTMDSRLYMLAFLPFLSLL
VLIRNLRVLTIFSLLANVSMLVSLVIIAQHITQGI----PDPSRLPLA------------
TSWKTYPLFFGTAIFSFESIGVV-L-----PLENKMKDARHFPAILSLGMSIIT--ALYI
AIGALGYLRFGDNIRASITLNLPNCWL--YQSVKLLYIVGILCTYALQFYVPAEIIVPFT
VSRVSERWALPVDLSVRLAM--VCL----TCMLAILIPRLDLVLSLVGSVSSSALALIIP
PLLEIATYSSEGLC-PLTIAKDALISILGFVGFVTGTYQALDELIESEESLPSSNST---
IFNQ-----------------------

------------------------------------------------------------
------------------------------------------LLP-------T------N
SMSFPPSPRM

PF01490 // ENSGT00390000011245_0_Domain_1 (131, 700)

MRTLTHLLKCNIGTGLLGLPLAMKNAGLLVGPLSLLAIGILTVHCMVI--
LLNCSH--HL-------SQR----------------------------------------
-----------------LQKTFVSYG--EAMMYSLESCPNTWLRTH--SVWG--------
-------------------------------------------------RYTVNFLLIIT
QLGFCCVYFMFMADNLQQVMEEAHMTSNTCHPRT--IPVLTPLLDIRLYMLSILPFLILL
VFIQNLRALSFFSTLANITTLGSMALIFEYIMQGI----PDPRNLPLV------------
AGWKTFLLFFGTAIFTFEGISMV-L-----PLKNQMKHPQQFSFVLYLGMSLVI--ILYI
CLGTLGYMKFGSDTQASITLNLPNCWL--YQSVKLMYSFGIFFTYALQFYVPAEIIIPFA
ISQVSESWALFADLSIRTGL--VCL----TCISAILIPHLDLIISLVGSVSSSALALIIP
PFLEIFTFYPEDMS-CITITKDIMISIMGLLGCIFGTYQALYELNQPINHTI-ANSTGA-
------------YA-------------

--------------------------------------------------MSVTKSAGSP
QVAATVKLDLVSSPESTK---KMQSQDPS-VANE--N-SSES------------------
-SKKTKG

PF01490 // ENSGT00390000011245_0_Domain_1 (128, 700)

ITGFQTLVHLVKGNMGTGILGLPLAVKNAGILMGPLSLLVMGLIACHCMHI--
LVRCAQ--RF-------CHR----------------------------------------
-----------------LNKPFMDYG--DTVMHGLEASPNVWLRNH--AHWGRYIVSFFL
IV---------------------------------------------------------T
QLGFCCVYIVFLADNLKQVVEAVNGTTFSCCNNET-V-ALMPTMDSRLYMLTFLPVLGLL
VFIRNLRVLTIFSLLANISMLVSLIIIAQYIIQGI----PDPSQLPLV------------
ASWKTYPLFFGTAIFSFESIGVV-L-----PLENKMKDARRFPTILSLGMSIIT--TLYI
AIGALGYLRFGDDIKASITLNLPNCWL--YQSVKLLYVVGILCTYALQFYVPAEIIIPLA
VSQVSKRWALPVDLSIRLAM--VCL----TCMLAILIPRLDLVLSLVGSVSSSALALIIP
PLLEVTTYYSEGLS-PLTITKDAFISILGFVGFVVGTYQALDELIESGNSLPLSNST---
MFIQ-----------------------

------------------------------------------------------------
-----------------MSTERLRNEDYQDYSSTDAS-PEESPSEG-L-GNFS-PGAYQR
FGES-N

PF01490 // ENSGT00390000011245_0_Domain_1 (127, 699)

NTTWFQTLIHLLKGNIGTGLLGLPLAVKNAGILLGPLSLLVIGVVAVHCMGI--
LVKCAH--HF-------CHR----------------------------------------
-----------------LNKPFVDYG--DTVMYGLEASPSPWLRNH--AHWGRRTVDFFL
IV---------------------------------------------------------T
QLGFCCVYFVFLADNFKQVVEAANRTTNNCHNNET-V-ILTPTMDSRLYMLAFLPFLVLL
VFIRNLRVLSIFSLLANMSMLVSLVMIYQFIVQRI----PNPSHLPLV------------
ASWRTYPLFFGTAIFAFEGIGMV-L-----PLENKMKDPQKFPLILYLGMAIVT--VLYI
SLGSLGYLQFGASIQGSITLNLPNCWL--YQSVKLLYSIGIFFTYGLQFYVPAEIIIPFF
VSRAPEQCRLLVDLSVRTAM--VCL----TCMLAILIPRLDLVISLVGSVSSSALALVIP
PLLEIATYSSEGLR-PLTIAKDALISVLGFAGFMVGTYEALAELAQPSAAPNSTNS--TG
AFAY-----------------------

------------------------------------------------------------
-----------------MSTQRLRNEDYHDYSSTDVS-PEETPSEG-L-GNFS-PGSYQR
LGES-N

PF01490 // ENSGT00390000011245_0_Domain_1 (127, 699)

STTWFQTLIHLLKGNIGTGLLGLPLAVKNAGLLLGPLSLLVIGIVAVHCMGI--
LVKCAH--HL-------CRR----------------------------------------
-----------------LNKPFLDYG--DTVMYGLECSPSAWVRSH--SHWGRRIVDFFL
IV---------------------------------------------------------T
QLGFCCVYFVFLADNFKQVIEAANGTTTNCHNNET-V-VLVPTMDSRLYMLVFLPFLVLL
TFIRNLRILSIFSLLANVSMLVSLVTIYQFIVQSI----PDPSHLPLV------------
APWKTYPLFFGTAIFAFEGIGVV-L-----PLENKMKDSQKFPFILYFGMAIVT--ALYI
SLGSLGYLQFGASIKGSITLNLPNCWL--YQSVKLLYSIGIFFTYALQFYVAAEIVIPVI
ESRVPERCKMVVDLCVRTAM--VCI----TCVLAILIPRLDLVISLVGSVSSSALALIIP
PLLEVTTYYGEGMS-PLTIIKDALISILGFVGFVVGTYESLCELIQPSHGEISTNS--TS
AFL------------------------

--------------------------------------------------MSVTK---ST
EGAIAVKLDLMSPPESAK---KLENKDST-FLDE--S-PSESP-----------------
GLKKTK

PF01490 // ENSGT00390000011245_0_Domain_1 (127, 700)

GITVIQALIHLVKGNMGTGILGLSLAVKNAGILMGPLSLLVMGLIACHCMHI--
LVRCAQ--RF-------CKR----------------------------------------
-----------------LNKPFMDYG--DTVMHGLEASPSAWLQNH--AHWGRHIVSFFL
IV---------------------------------------------------------T
QLGFCCVYIVFLADNLKQVVEAVNSTTNNCHSNET-V-ILTPTMDSRLYMLSFLPLLVLL
VFIRNLRILTIFSMLANISMLVSLVIITQYITQEI----PDPSRLPLV------------
ASWKTYPLFFGTAIFSFESIGVV-L-----PLENQMKNARHFPAILSLGMSIVT--SLYI
SIATLGYLRFGDDIKASISLNLPNCWL--YQSVKLLYIAGILCTYALQFYVPAEIIIPFA
ISRVSTRWALPLDLSIRLAM--VCL----TCILAVLIPRLDLVISLVGSVSSSALALIIP
PLLEVTTFYSEGMS-PLTIFKDALISILGFVGFVVGTYQALDELLKSGDSPPFSNST---
TFLR-----------------------

--------------------------------------------------MSVTK---ST
EGAVAVKLDLMSPPESAK---KLENKDST-FLDE--S-PSESP-----------------
GLKKTK

PF01490 // ENSGT00390000011245_0_Domain_1 (127, 597)

GITVIQALIHLVKGNMGTGILGLSLAVKNAGILMGPLSLLVMGLIACHCMHI--
LVRCAQ--RF-------CKR----------------------------------------
-----------------LNKPFMDYG--DTVMHGLEASPSAWLQNH--AHWGRHIVSFFL
IV---------------------------------------------------------T
QLGFCCVYIVFLADNLKQVVEAVNSTTNNCHSNET-V-ILTPTMDSRLYMLSFLPLLVLL
VFIRNLRILTIFSMLANISMLVSLVIITQYITQEI----PDPSRLPLV------------
ASWKTYPLFFGTAIFSFESIGVV-L-----PLENKMKNARHFPAILSLGMSIVT--SLYI
SIATLGYLRFGDDIKASISLNLPNCWL--YQSVKLLYIAGILCTYALQFYVPAEIIIPFA
ISQVSTRWALPLDLSIRLAM--VCL----TCE----------------------------
------------------------------------------------------------
---------------------------

-----------------------------------------------------MS-----
-------LLGRD-----Y-NSELNS-----LDNRSQS-PSESSS-S-ITS-----E-NVH
PA-GEAG

PF01490 // ENSGT00390000011245_0_Domain_1 (128, 700)

LSMMQTLIHLLKCNIGTGLLGLPLAIKNAGLLVGPVSLLAIGVLTVHCMVI--
LLNCAQ--HL-------SQR----------------------------------------
-----------------LQKTFVNYG--EATMYSLETCPNTWLRTH--AVWGKWSSAVSH
-RLECSGKI---------SAHC---NPHLQGS-SDS--PAQAS-VAEIYRYTVSFLLIIT
QLGFCSVYFMFMADNLQQMVEEAHVTSNICQPRE--ILALTPILDIRFYMLTILPFLILL
VFIQNLKVLSVFSTLANITTVGSMALIFEYIMQGI----PYPSNLPLM------------
ANWKTFLLFFGTAIFTFEGVGMV-L-----PLKNQMKHPQQFSFVLYLGMSIVI--ILYI
FLGTLGYMKFGSDTQASITLNLPNCWL--YQSVKLMYSIGIFFTYALQFHVPAEIIIPFA
VSQVSESWALFVDLSVRSGL--VCL----TCVSAILIPRLDLVISLVGSVSSSALALIIP
ALLEIVIFYSEDMS-CVTLAKDIMISILGLLGCIFGTYQALYELTQPINHSM-ANSTGVY
A--------------------------

------------------------------------------------------------
-----------------MSTQRLRNEDYHDYSSTDVS-PEESPSEG-L-SHLSSPGSYQR
FGQS-N

PF01490 // ENSGT00390000011245_0_Domain_1 (127, 455)

STTWFQTLIHLLKGNIGTGLLGLPLAVKNAGIVMGPVSLLVIGIIAVHCMGI--
LVKCAH--HF-------CRR----------------------------------------
-----------------LNKSFVDYG--ETVMYGLESSPCSWLRNH--AHWGRHVVDFFL
IV---------------------------------------------------------T
QLGFCCVYFVFLAENFK-------------------------------------------
--------------------------------QRI----PDPSNLPLV------------
APWKTYPLFFGTAIFAFEGIGMV-L-----PLENKMKDPRKFPLILYLGMAIVT--ILYI
SLGCLGYLQFGANIQGSITLNLPNCWL--YQSVKLLYSIGIFFTYALQFYVPAEIIIPFF
VSRAPEHCELAVDLFVRTVL--VCL----TCILAILIPRLDLVISLVGSVSSSALALIIP
PLLEVTTFYSEGMS-PLAIFKDALISILGFVGFVVGTYEALYELIQPSNAPIFINS--TR
AFI------------------------

-----------------------------------------------------ML-----
-------LLGRD-----Y-NSELNS-----LDNGPQS-PSESSS-S-ITS-----E-NVH
PA-GEAG

PF01490 // ENSGT00390000011245_0_Domain_1 (128, 700)

LSMMQTLIHLLKCNIGTGLLGLPLAIKNAGLLVGPVSLLAIGVLTVHCMVI--
LLNCAQ--HL-------SQR----------------------------------------
-----------------LQKTFVNYG--EATMYGLETCPNTWLRAH--AVWGRWNLALSP
-RLECSGNI---------SAHC---NPHLQGS-SNS--PAQASQVAGIYRYTVSFLLVIT
QLGFCNVYFMFMADNLQQMVEEAHVTSNICQPRE--ILTLTPILDIRFYMLIILPFLILL
VFIQNLKVLSIFSTLANITTLGSMALIFEYIMQGI----PYPSNLPLM------------
ANWKTFLLFFGTAIFTFEGVGMV-L-----PLKNQMKHPQQFSFVLYLGMSIVI--ILYI
LLGTLGYMKFGSDTQASITLNLPNCWL--YQSVKLMYSIGIFFTYALQFHVPAEIVIPFA
ISQVSESWALFVDLSVRSAL--VCL----TCVSAILIPRLDLVISLVGSVSSSALALIIP
ALLEIVIFYSEDMS-CVTIAKDIMISIVGLLGCIFGTYQALYELPQPISHSM-ANSTGVH
A--------------------------

------------------------------------------------------------
-----------------MSTRRLRSEDYNDYSSTDVT-PEGSPPDG-M-NGFAHPESYQR
FGET-N

PF01490 // ENSGT00390000011245_0_Domain_1 (127, 700)

GTTWYQTLIHLLKGNIGTGLLGLPLAVKNAGILLGPLSLLVMGVVAVHCMGI--
LVKCAH--HF-------CNR----------------------------------------
-----------------FQKQFLDYG--GAVMYGLEATPSACLRTH--AIWGRRVVGLFL
II---------------------------------------------------------T
QLGFCCVYFVFLADNLKQVVSAANGTTNDCSANRT-V-VMTPTMDSRLYMLSILPFVVLL
TFIQNLKVLSIFSMLANVAMLVSLVVIYQYIVRDI----PDPRNLPLA------------
AAWKTYPLFFGTAIFAFEGIGVV-L-----PLENKMKNPRQFPVILYVGMTIVT--ILYI
SLSVLGYLRFGTDIQASITLNLPNCWL--YQAVKLLFSFGIFFTYAVQFYVPAEIIIPPL
VARVSERWGWLVNLLLRVAL--VCV----TCVLAILIPRLDLVISLVGSISSSALALIFP
PLLEIATYYSEGMH-PLVIAKDITISLFGFVGFVVGTYEALVELV----APAATVVNATT
VLV------------------------

--------------------------------------------------MLETS-----
-------LAGKE-----C-SSEPSS-----SAVGSKS-SSASSHS-------LTPD-KGQ
PAGEAAG

PF01490 // ENSGT00390000011245_0_Domain_1 (128, 700)

LSMVQTLIHLLKCNVGTGLLGLPLAIKNAGLLVGPFSLLAIGVLTVHCMVI--
LLNCAH--HL-------TQR----------------------------------------
-----------------LHKTFVNYG--EAMMYSLETCPNPWLRAH--SAWGR-------
--------------------------------------------------YIVSFLLIIT
QLGFCSVYFMFMADNLQQIAEEAHVTSRTCQPRK--ILVLRPILDIRFYMLIILPFLILL
VFVQNLKVLSIFSTLASVTTLGSMALIFEYIVQGI----PFPSDLPLM------------
ANWETFLLFFGTALFTFEGVGMV-L-----PLKNQMKNPQQFSFVLYMGMSLVI--ILYI
FLGTLGYMKFGADTQASITLNLPNCWL--YQSVKLMYSVGIFFTYALQFHVPAEIIIPFA
ISQVSESWTLCVDLSVRTAL--VCL----TCVSAILIPRLDLVISLVGSVSSSALALIIP
PLLEITTFYSEDLS-CATIAKDIMISILGFLGCIFGTYQALYDLIQPVNHSI-ANSTGVY
A--------------------------

-----------------------------------------------------MS-----
-------LLGRD-----Y-NSELNS-----LDNRSQS-SSESSS-S-ITS-----E-NVH
PA-GEAG

PF01490 // ENSGT00390000011245_0_Domain_1 (128, 700)

LSMMQTLIHLLKCNIGTGLLGLPLAIKNAGLLVGPVSLLAIGVLTVHCMVI--
LLNCAQ--HL-------SQR----------------------------------------
-----------------LQKTFVNYG--EATMYSLETCPDAWLRTH--AVWGRY------
---------------------------------------------------TVSFLLIIT
QLGFCSVYFMFMADNLQQMVEEAHVTSNICQPRE--ILALTPILDIRFYMLTILPFLILL
VFIQNLKVLSVFSTLANITTVGSMALIFEYIMQGI----PYPSNLPLM------------
ANWKTFLLFFGTAIFTFEGVGMV-L-----PLKNQMKHPQQFSFVLYLGMSIVI--ILYI
FLGTLGYMKFGSDTQASITLNLPNCWL--YQSVKLMYSIGIFFTYALQFHVPAEIIIPFA
VSQVSENWALFVDLSVRSGL--VCL----TCVSAILIPRLDLVISLVGSVSSSALALIIP
ALLEIVIFYSEDMS-CVTLAKDIMISILGLLGCIFGIYQALYELTQPINHSM-ANSTGVY
A--------------------------

------------------------------------------------------------
-----------------MSTQRLRNEDYQDYSSTDAS-PEESPSES-L-GTFA-PGAYQR
FGES-N

PF01490 // ENSGT00390000011245_0_Domain_1 (127, 699)

STTWFQTLIHLLKGNIGTGLLGLPLAVKNAGILLGPLSLLVIGVAAVHCMGL--
LVNHCLI-HTLCPCPFPSPR----------------------------------------
-----------------LNKPFVDYG--DTVMYGLESSPSAWLRNH--AHWGRRVVDFFL
IV---------------------------------------------------------T
QLGFCCVYFVFLADNFKQVVEAANSTTTNCHNNET-V-ILTPTMDSRLYMLALLPFLVLL
VFIRNLRVLSIFSLLANISMLVSLILIYQFIVQGL----PNPSHLPLV------------
APWKTYPLFFGTAIFAFEGIGMV-L-----PLENKMKDPQKFPFILYLGMAIVT--IVYI
SLGSLGYLQFGASIQGSITLNLPNCWL--YQSVKLLYSIGIFFTYGLQFYVPAEIIVPFF
VSRAPEPCQLLVDLAVRTAM--VCL----TCILAVLIPRLDLVISLVGSVSSSALALVIP
PLLEVITYSSEGLG-PLTLAKDALISILGFVGFVVGTYESLAELIQPTAAPMSTNS--SR
AFAYGAGLLL-----------------

-----------------------------------------------------MP-----
-------LLGRD-----Y-KSELNS-----LDDGSKS-PSRSGS-------STTPR-NVP
PAAEA

PF01490 // ENSGT00390000011245_0_Domain_1 (126, 705)

SELSTMQTLIHLLKCNIGTGLLGLPLAIKNAGLLVGPVSLLAIGVLTVHCMAI--
LLNCAG--HL-------GQR----------------------------------------
-----------------LQKIFVNYG--DAMMYSLETCPHPWLRTH--SMWGRY------
---------------------------------------------------IVNFLLIIT
QLGFCSVYFMFMADNLQQMVEEAHATSNTCRPRK--TLVLTSILDIRFYMLTILPFLVLL
VFIQNFKLLSFFSTLANITTLGSMALIFEYIIQGI----PYPSNLPLV------------
ANWKTFLLFFGTAIFTFEGVGMV-L-----PLKNQMKHPQEFSFVLYLGMSLVI--IIYI
CLGTLGYLKFGSDTQVSITLNLPNCWL--YQSVKLMYSIGIFFTYALQFHISAEIIIPFA
ISQVAESWALFVDLSVRTAL--VCL----TCISAILIPRLDLVISLVGSVSSSALALIIP
PVLEI-TLYSAGMS-PATIAKDIMSILALGYIC-------TYQPRGVAQHSH-MHSTAVY
A--------------------------

--------------------------------------------------MSVTK---ST
EGAVAVKLDLMSPPESAK---KLENKDST-FLDE--S-PSESP-----------------
GLKKTK

PF01490 // ENSGT00390000011245_0_Domain_1 (127, 700)

GITVIQALIHLVKGNMGTGILGLSLAVKNAGILMGPLSLLVMGLIACHCMHI--
LVRCAQ--RF-------CKR----------------------------------------
-----------------LNKPFMDYG--DTVMHGLEASPSAWLQNH--AHWGRHIVSFFL
IV---------------------------------------------------------T
QLGFCCVYIVFLADNLKQVVEAVNSTTNNCHSNET-V-MLTPTMDSRLYMLSFLPFLVLL
VLIRNLRILTIFSMLANISMLVSLVIITQYITQEI----PDPSRLPLV------------
ASWKTYPLFFGTAIFSFESIGVV-L-----PLENKMKNARHFPAILSLGMSIVT--SLYI
SIGTLGYLRFGDDIKASISLNLPNCWL--YQSVKLLYIAGILCTYALQFYVPAEIIIPFA
ISRVSTRWALPLDLSIRLAM--VCL----TCLLAVLIPRLDLVISLVGSVSSSALALIIP
PLLEVSTFYSEGMS-PLTIFKDALISILGFVGFVVGTYQALDELLKSGDSPLFSNST---
TFLR-----------------------

------------------------------------------------------------
-----------------MSTQRLRNEDYHDYSSTDVS-PEESPSEG-L-NNFSSQGSYQR
FGES-N

PF01490 // ENSGT00390000011245_0_Domain_1 (127, 699)

STTWFQTLIHLLKGNIGTGLLGLPLAVKNAGILMGPLSLLVIGLVAVHCMGI--
LVKCAH--HF-------CRR----------------------------------------
-----------------LNKPFVDYG--DTVMYGLESSPSSWLRNH--AHWGRHIVDFFL
IV---------------------------------------------------------T
QLGFCCVYFVFLADNFKQVIEAANGTTNNCHNNET-V-ILTPTMDSRLYMLTFLPFLVLL
VFVRNLRALSIFSLLANITMLVSLVMLYQFIVQNI----PDPSRLPLV------------
APWKTYPLFFGTAIFAFEGIGMV-L-----PLENKMKDPQKFPLILYVGMAIIT--ALYI
SLGCLGYLQFGANIQGSITLNLPNCWL--YQSVKLLYSVGIFFTYALQFYVPAEIIIPFF
VSRVPEHWELVVDLFVRTVL--VCM----TCILAILIPRLDLVISLVGSVSSSALALIIP
PLLEITTYYSEGMS-PFTIAKDALISILGFVGFVVGTYEALYELIQPSNAPIVINS--TG
AFV------------------------

------------------------------------------------------------
-----------------MSTQRLRNEDYHDYSSTDVS-PEESPSEG-L-SHLSSPGSYQR
FGQS-N

PF01490 // ENSGT00390000011245_0_Domain_1 (127, 699)

STTWFQTLIHLLKGNIGTGLLGLPLAVKNAGIVMGPVSLLVIGIIAVHCMGI--
LVKCAH--HF-------CRR----------------------------------------
-----------------LNKSFVDYG--ETVMYGLESSPCSWLRNH--AHWGRHVVDFFL
IV---------------------------------------------------------T
QLGFCCVYFVFLAENFKQVVEAANGTTNNCHNNET-V-ILTPTMDSRLYMLSFLPFLVLL
VFVRSLRALSVFSLLANITMLVSLIMIYQFIVQRI----PDPSNLPLV------------
APWKTYPLFFGTAIFAFEGIGMV-L-----PLENKMKDPRKFPLILYLGMAIIT--ILYI
SLGCLGYLQFGNNIQGSITLNLPNCWL--YQSVKLLYSIGIFFTYALQFYVPAEIIIPFF
VSRAPEHCELVVDLFVRTVL--VGL----TCILAILIPRLDLVISLVGSVSSSALALIIP
PLLEVTTFYSEGMS-PLTIFKDALISILGFVGFVVGTYEALYELIQPSNAPIFINS--TR
AFI------------------------

------------------------------------------------------------
-----------------MSTQRLRNEDYHDYSSTDVS-PEDSPSEG-L-NNLSSPGSYQR
FGQS-N

PF01490 // ENSGT00390000011245_0_Domain_1 (127, 450)

STTWFQTLIHLLKGNIGTGLLGLPLAVKNAGIVMGPISLLVIGIVAVHCMGI--
LVKCAH--HF-------CRR----------------------------------------
-----------------LNKSFVDYG--DTVMYGLESSPCSWLRNH--AHWGRRVVDFFL
IV---------------------------------------------------------T
QLGFCCVYFVFLADNFKQVIEAANGTTNNCHNNET-V-ILTPTMDSRLYMLSFLPFLVLL
VFIRNLRALSVFSLLANITMLVSLIMIYQFIVQ---------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------

------------------------------------------------------------
-----------------MDTSRLTSDRYNDYSSTEAS-PSEESPPGTISNYVSGPRRYQR
LGEDS

PF01490 // ENSGT00390000011245_0_Domain_1 (126, 638)

SSTTWYQTLIHLLKGNIGTGLLSLPLAVKNAGIVLGPLSLVFMGIIAVHCMDL--
LVKCAH--HL-------CQR----------------------------------------
-----------------NQRPFVDYG--DALMYSMQGSPSQWLQRH--SVWGRRIVGFFL
IL---------------------------------------------------------T
QLGFCCVYFVFLADNIKQVVEAANGTTNDCSSNET-L-VLVESMDSRLYILSFLPFLILL
VFITNLRYLSIFSLLANLSMLGSVIMIYQYIGRDI----PDPTSLSFV------------
SSWRSYALFFGTAIFAFEGIGVV-L-----PLENKMKIPHQFPVVLYVGMGIVT--ILYI
SMGTLGYLRFGSSIQASITLNLPNCWF--YQSVKLLYSFGIFITFALQFYVAAEIIVPAV
TLHVHDRWVRCMDLTVRAAL--VCI----TCKCYILMVTL--------------------
------------------------------------------------------------
---------------------------

------------------------------------------------------------
-----------------MSTQRLRNEDYHDYSSTDVS-PEESPSEG-L-NSFS-SGSYQR
FGEG-N

PF01490 // ENSGT00390000011245_0_Domain_1 (127, 699)

STTWFQTLIHLLKGNIGTGLLGLPLAVKNAGILMGPLSLLVMGIVAVHCMGI--
LVKCAH--HF-------CHR----------------------------------------
-----------------LNKPFVDYG--DTVMYGLESSPSSWLRNH--AHWGRHIVDFFL
IV---------------------------------------------------------T
QLGFCCVYFVFLADNFKQVIEAANGTTSDCHNNET-V-VLTPTVDSRLYMLAFLPFLVLL
VFIRNLRVLSVFSLLANISMLVSLVMIYQFIVQRI----PNPSHLPLV------------
APWKTYPLFFGTAIFAFEGIGMV-L-----PLENKMKDPRKFPIILYTGMTIVT--ALYI
SLGCLGYLQFGANIQGSITLNLPNCWL--YQSVKLLYSVGIFFTYALQFYVPAEIIIPFF
VSRAPEHCELVVDLFVRTVL--VCL----TCVLAVLIPRLDLVISLVGSVSSSALALIIP
PLLEITTYYSEGMS-PLTIAKDALISILGFTGFVVGTYEALYELIQPSNAPIFINS--TS
AYV------------------------

------------------------------------------------------------
------------------------------------------------------------
---------P

PF01490 // ENSGT00390000011245_0_Domain_1 (131, 700)

TQALIHLLKCSIGTGLLGLPLAVKNAGLLVGPVSLLAIGILTVHCMVI--
LLNCAH--HL-------TQR----------------------------------------
-----------------LQKTFMNYG--ETTMYSLENCSSSWLRTH--SVWGRY------
---------------------------------------------------TVSSLLIIT
QLGFCSVYFMFMADNLQQIVEEAHIISNTCQPRK--ILVLTPILDIRVYMLTILPFLIML
AFIQNLKVLSIFSTLANITTLGSMALIFEYIVQ-I----PYPINLPLM------------
ANWKTFLLFFGTTIFTFEGVGMV-L-----PLKNQMKNPQKFSFVLYLGMSLVI--FLYI
CLGTLGYMKFGPDTQASIMLNLPNCWL--YQSVKVMYSIGIFFTYALQFHVPAEIIIPFA
ISQVSESWALPVDLSVRTAL--VCL----TCVSAILIPRLDLVISLVGSVSSSALALIIP
PLLEIITFYPEDMS-CVTIAKDIMISMLGLLGCILGTYQALYEFTQPVNRSM-ANSTVIY
A--------------------------

------------------------------------------------------------
-----------------MSTQRLRNEDYHDYSSTDVS-PEESPSEG-L-GSFS-PGSYQR
LGEN-SS

PF01490 // ENSGT00390000011245_0_Domain_1 (128, 699)

MTWFQTLIHLLKGNIGTGLLGLPLAVKNAGLLLGPLSLLVIGIVAVHCMGI--
LVKCAH--HL-------CRR----------------------------------------
-----------------LNKPFLDYG--DTVMYGLECSPSTWVRSH--SHWGRRIVDFFL
IV---------------------------------------------------------T
QLGFCCVYFVFLADNFKQVIEAANGTTTNCNNNVT-V-IPTPTMDSRLYMLSFLPFLVLL
SFIRNLRILSIFSLLANISMFVSLIMIYQFIVQRI----PDPSHLPLV------------
APWKTYPLFFGTAIFAFEGIGVV-L-----PLENKMKDAQKFPLILYLGMAIVT--VLYI
SLGSLGYLQFGANIKGSITLNLPNCWL--YQSVKLLYSIGIFFTYALQFYVAAEIIIPAI
VSRVPEHFELMVDLCVRTAM--VCV----TCVLAILIPRLDLVISLVGSVSSSALALIIP
PLLEVATYYGEGIS-PLTITKDALISILGIVGFVVGTYESLCELIQPSHSDSSTNS--TS
AFI------------------------

------------------------------------------------------------
--TVTFSSSPVIAPDSNWKNKDNNSKNES-TLEGGSN-GSDPN-----------------
SSQNVK

PF01490 // ENSGT00390000011245_0_Domain_1 (127, 700)

GTTWWQTVIHLVKGNIGTGLLGVPLAAKQGGLLIGCLGLLAMGIVAVHCMGL--
MVKCAQ--HL-------GRR----------------------------------------
-----------------VQKPFLDYS--DAVMYGLKTSPFPWFQKH--AIWGRHVVSFFL
IL---------------------------------------------------------T
QLGFCCVYFVFLADNIKQVIEAANATTSDCFSNTT-V-TLTPSMDSRFYILSLLPFFVLL
VFVRNLRILSIFSMVANICMIASLVVIFHYLLQDI----PDPSSLPMF------------
SELKTYALFFGTAAFAFESIGVV-L-----PLENQMKKREQFPFILYMGMSVVI--IAYV
ILAFLGYLKFGAATQASITLNLPNCWL--FQTVKLLYSLGIFFTYSLQFYVPAGIILPVV
LSRVPKKWNLMAEYSIRVGL--VCI----TCFLGILVPRLDLVIALVGSTSSSALALIFP
PFLEIITFYSEGLN-PIIIIKDILICLLGFCGFLVGTYQALYELTHSPVSPTFANYT---
STFVQ----------------------

------------------------------------------------------------
-----------------MSTQRLRNEDYHDYSSTDVS-PEESPSEG-L-TNFSAPGSYQR
FGES-

PF01490 // ENSGT00390000011245_0_Domain_1 (126, 702)

NSTTWFQTLIHLLKGNIGTGLLGLPLAVKNAGLLMGPLSLLLIGIVAVHCMGI--
LVKCAH--HF-------CRR----------------------------------------
-----------------LNKPFVDYG--DTVMYGLESSPSSWLRNH--AHWGRHIVDFFL
IV---------------------------------------------------------T
QLGFCCVYFVFLADNFKQVIEAANGTTNNCHNNET-V-ILTPTMDSRLYMLTFLPFFVLL
VFIRNLRVLSIFSLLANISMLVSLVMIYQFIVQRI----PNPSRLPLV------------
APWKTYPLFFGTAIFAFEGIGMV-L-----PLENKMKDPRKFPLILYVGMAIIT--ALYI
SLGCLGYLQFGASIQASITLNLPNCWL--YQSVKLLYSIGIFFTYALQFYVPAEIIIPFF
VSRVPEHCELVVDLFVRTML--VCL----TCILAILIPRLDLVISLVGSVSSSALALIIP
PLLEITTYYSEGMS-PLVIAKDAVISIVGFVGFVVGTYEALYELIQPSNAPISINS--TS
AFI------------------------

--------------------------M------------------ESPFHLILSI-----
-------FPPEG-----A-RETERS-----PSAGSR----------------FLPL-TYP
FLVLCSPYR

PF01490 // ENSGT00390000011245_0_Domain_1 (130, 700)

MMQTLIHLLKCNIGTGLLGLPLAMKNAGLLVGPVSLLAIGILTVHCMVI--
LLNCAH--HL-------SQR----------------------------------------
-----------------LQKTFVNYG--EAMMYSLQTCPNAWLRTH--SVWGR-------
--------------------------------------------------YTVSFLLIIT
QLGFCSVYFMFMADSLQQMVEEAHVTSKTCEPRK--ILVLTPNVDIRFYMLTILPFLILL
VFIQNLRVLSIFSTLANITTLGSMALIFQYIMQ-I----PDPRNLPLM------------
ASWKTFLLFFGTAIFTFEGVGMV-L-----PLKNQMKHPQQFSFVLYLGMSLVI--VLYI
CLGTLGYMKFGSNTQASITLNLPNCWL--YQSVKLMYSIGIFFTYALQFHVPAEIIIPII
ISQVSESWALFADLSVRTAL--VCL----TCVSAILIPRLDLVISLVGSVSSSALALIIP
PFLELITFYPEDMN-CITIVKDIMISILGLLGCVFGTYQALYELTQPINHSV-ANSTGVY
A--------------------------

--------------------------------------------------MSETKSTEGP
QGAVAIKLDLMSPPESAK---KLENKDST-FLDE--S-PSESA-----------------
GLRKTK

PF01490 // ENSGT00390000011245_0_Domain_1 (127, 700)

GITVFQTLIHLVKGNMGTGILGLPLAVKNAGILMGPLSLLVMGFIACHCMHI--
LVKCAQ--RF-------CKR----------------------------------------
-----------------LNKPFMDYG--DTVMHGLEANPNVWLQNH--AHWGRHIVSFFL
IV---------------------------------------------------------T
QLGFCCVYIVFLADNLKQVVEAVNSTTNNCYSNET-V-ILTPTMDSRLYMLSFLPFLVLL
VLIRNLRILTIFSMLANISMLVSLVIIIQYITQEI----PDPSRLPLV------------
ASWKTYPLFFGTAIFSFESIGVV------LPLENKMKNARHFPAILSLGMSIVT--SLYI
GMAALGYLRFGDDIKASISLNLPNCWL--YQSVKLLYIAGILCTYALQFYVPAEIVTPFA
ISRVSTRWALPLDLSIRLVM--VCL----TCLLAILIPRLDLVISLVGSVSGSALALIIP
PLLEVTTFYSEGMN-PLTIFKDALISILGFVGFVVGTYQALDELLKSGDSHPFSNST---
TFVR-----------------------

-----------------------------------------------------MS-----
-------LLGRD-----Y-NSELNS-----LDNRSQS-PLESSN-S-ITS-----E-NVH
PA-GEAG

PF01490 // ENSGT00390000011245_0_Domain_1 (128, 700)

LSTMQTLIHLLKCSIGTGLLGLPLAMKNAGLLVGPVSLLAIGVLTVHCMVI--
LLNCAQ--HL-------SQR----------------------------------------
-----------------LQKTFVNYE--EATMYSLETCPNTWLRTH--AVWGRWSLALSP
-RLECSGKI---------SAHC---NLHLQGS-SNS--PAQASRVAEIYRYTVSFLLIIT
QLGFCSVYFMFMADNLQQMVEEAHVTSNICQPRE--TLALTPILDIRVYMLTILPFLILL
VFIQNLKVLSVFSTLASITTVGSMALIFEYIMQGI----PYPSNLPLM------------
ANWKTFLLFFGTAIFTFEGVGMV-L-----PLKNQMKHPQQFSFVLYLGMSIVI--ILYI
FLGTLGYMKFGSDTQASITLNLPNCWL--YQSVKLMYSIGIFFTYALQFHVPAEIIIPFA
ISQVSESWALFVDLSVRSAL--VCL----TCVSAILIPRLDLVISLLGSVSSSALALIIP
ALLEIVIFYSKDMS-CVTLAKDIMISILGLLGCIFGTYQALYELTQPINHSM-ANSTGVY
A--------------------------

------------------------------------------------------------
-----------------MSTQRLRNEDYHDYSSTDVS-PEESPSEG-L-GSFS-PGSYQR
LGEN-SS

PF01490 // ENSGT00390000011245_0_Domain_1 (128, 699)

MTWFQTLIHLLKGNIGTGLLGLPLAVKNAGLLLGPLSLLVIGIVAVHCMGI--
LVKCAH--HL-------CRR----------------------------------------
-----------------LNKPFLDYG--DTVMYGLECSPSTWVRNH--SHWGRRIVDFFL
IV---------------------------------------------------------T
QLGFCCVYFVFLADNFKQVIEAANGTTTNCNNNVT-V-IPTPTMDSRLYMLSFLPFLVLL
SFIRNLRVLSIFSLLANISMFVSLIMIYQFIVQRI----PDPSHLPLV------------
APWKTYPLFFGTAIFAFEGIGVV-L-----PLENKMKDSQKFPLILYLGMAIIT--VLYI
SLGSLGYLQFGANIKGSITLNLPNCWL--YQSVKLLYSIGIFFTYALQFYVAAEIIIPAI
VSRVPEHFELMVDLCVRTAM--VCV----TCVLAILIPRLDLVISLVGSVSSSALALIIP
PLLEVVTYYGEGIS-PLTVTKDALISILGFVGFVVGTYESLCELIQPSHSDSSTNS--TS
AFI------------------------

--------------------------------------------------MPVTKSAQGP
QGAVDLKLDLRGPPENAK---KLQNKDSS-FLNG--N-PSESP-----------------
DSEKTKG

PF01490 // ENSGT00390000011245_0_Domain_1 (128, 700)

ITEFQTLVHLLKSNIGTGILGLPLAVRNAGILMGPLSLLAIGFISTHCMYI--
LVRCAQ--RF-------CHR----------------------------------------
-----------------LNKPFLDYG--DTVMYGLKAGPSAWLQNH--AHWGRRIVSFFL
IV---------------------------------------------------------T
QLGFCCVYIVFLADNLKQVMDAVNSTTNSCHYNET-V-IPTHTMDSRLYMLSFLPFLVLL
AFVRNLRVLTIFSMLANISMLVSLIILTQYIVQGI----PDPRGLPLV------------
ASWNTYPLFFGTAMFSFESIGVV-L-----PLENKMKDARRFPAILYLGMSIVT--AMYI
GIGALGYLRFGNDIKASITLNLPNCWL--YQSVKLLYVFGILCSYSLQFYVPAEIIVPFA
VSRVSKRWALPLDLSIRLAM--VCL----TCILAILIPRLDLVLSLVGSMSSSALALIIP
PLLEITTYYSEGMS-PLTIIKDVLISILGFVGLVVGTYQALDNLIQPTDHLTISNST---
IFTQ-----------------------

-MAGVGEP------------------------------GAAE-P-AVPMEPRVP---TGP
DV-----PADAAPSSGAMSTRRLRSEDYNDYSSTDVT-PEGSPPAG-I-NGFARPESYQR
FGES-N

PF01490 // ENSGT00390000011245_0_Domain_1 (127, 700)

GTTWYQTLIHLLKGNIGTGLLGLPLALKNAGILLGPLSLLVMGVVAVHCMSI--
LVKCAH--HF-------CYR----------------------------------------
-----------------FQKQFLDYG--GAVMYGLESTPISWLRTH--AVWGRRVVGLFL
IL---------------------------------------------------------T
QLGFCCVYFVFLADNLRQVVSSANSTTTDCQSNRT-V-TLMPTMDSRLYMLSLLPFVVLL
SFIQNLKVLSIFSMLANVAMLISLVVIYQYIVRDI----PDPKALPLA------------
AAWKTYPLFFGTAIFAFEGIGVV-L-----PLENKMKNPRQFPLILYVGMTIVT--ILYI
SLGVLGYLRFGAAIQASITLNLPNCWL--YQAVKLLFSFGIFFTYAVQFYVPAEIIIPPL
VARVSERWGWLVNLLLRVVL--VSI----TCALAILIPRLDLVISLVGSVSSSALALIFP
PLLEIATYYTEGMH-PLLIAKDVLISLFGFVGFVVGTYEALVELASP----AA-VINGTS
TSGQ-----------------------

------------------------------------------------------------
-----------------MSTQRLRNENYSGYSSTEVS-PTESPSNG-L-DDFSGSSSYQR
FGET-N

PF01490 // ENSGT00390000011245_0_Domain_1 (127, 701)

GTTWFQTLIHLLKGNIGTGLLGLPLAVKNAGILMGPLSLLLMGIVAVHCMGI--
LVKCAH--HF-------CQR----------------------------------------
-----------------LHKPFVDYG--DTVMYGLEASPSSWLRTH--SLWGRHIVDFFL
IV---------------------------------------------------------T
QLGFCCVYFVFLADNFKQVVEAANMTTNNCNSNET-V-LLTPTMDSRLYMLTFLPFLVLL
VFVRNLRALSIFSMLANISMLVSLVMIYQHIVQGI----PDPRNLPLV------------
ANWKTYPLFFGTAIFAFEGIGVV-L-----PLENKMKDPKHFPVILYVGMTIIT--ILYI
SLGCLGYLQYGPAIHASITLNLPNCWL--YQSVKLLYSIGIFFTYALQFYVPAEIIIPFF
VSRVTERWALMVELSVRIAM--VCL----TCVLAILIPRLDLVISLVGSVSSSALALIIP
PLLEIATYYSEGMS-PITIAKDILISVFGFVGFVVGTYQAIYELIQPSVSPTLANI--AS
AFVQ-----------------------

------------------------------------------------------------
-----------------MSTQRLRNEDYNDYSSTDVS-PEESPSEG-L-NNFSSPGSYQR
FGES-N

PF01490 // ENSGT00390000011245_0_Domain_1 (127, 699)

STTWFQTLVHLLKGNIGTGLLGLPLAVKNAGILMGPLSLLVIGIVAVHCMGI--
LVKCAH--HF-------CRR----------------------------------------
-----------------LNKPFVDYG--DTVMYGLESSPSSWLRNH--AHWGRHLVDFFL
IV---------------------------------------------------------T
QLGFCCVYFVFLADNFKQVIEAANGTTNNCHNNET-V-ILTPTMDSRLYMLTFLPFLVLL
VFVRNLRALSIFSLLANITMLVSLVMLYQFIVQNI----PDPSRLPLV------------
APWKTYPLFFGTAIFAFEGIGMV-L-----PLENKMKDPQKFPVILYVGMAIIT--ALYI
SLGCLGYLQFGANIQGSITLNLPNCWL--YQSVKLLYSIGIFFTYALQFYVPAEIIIPFF
VSRVPEHCELVVDLFVRTVL--VCL----TCVLAILIPRLDLVISLVGSVSSSALALIIP
PLLEITTYYSEGMS-PITIAKDALISILGFVGFVVGTYEALYELIQPSSAPVFINS--TS
AFV------------------------

-----------------------------------------------------MS-----
-------LLGRD-----Y-NSELNS-----LDNRSQS-PSESSS-S-ITS-----E-NVH
PA-GEAG

PF01490 // ENSGT00390000011245_0_Domain_1 (128, 700)

LSTMQTLIHLLKCNIGTGLLGLPLAMKNAGLLVGPVSLLAIGVLTVHCMVI--
LLNCAQ--HL-------SQR----------------------------------------
-----------------LQKTFVNYE--EATMYSLETCPNTWLRTH--AVWGRWSLALSP
-RLECSGKI---------SAHC---NPHLQGS-SDS--PAQASRVAEIYRYTVSFLLIIT
QMGFCSVYFMFMADNLQQMVEEAHVTSNICQPRE--TLALTPILDIRFYMLTILPFLILL
VFIQNLKVLSVFSTLANITTMGSMALIFEYIMQGI----PYPSNLPLM------------
ANWKTFLLFFGTAIFTFEGVGMV-L-----PLKNQMKHPQQFSFVLYLGMSIVI--ILYI
FLGTLGYMKFGSDTQASITLNLPNCWL--YQSVKLMYSIGIFFTYALQFHVPAEIIIPFA
VSQVSESWALFVDLSVRSAL--VCL----TCVSAILIPRLDLVISLLGSVSSSALALIIP
ALLEIVIFYSEDMS-CVTLAKDIMISILGLLGCIFGTYQALYELTQPINHSM-ANSTGVY
A--------------------------

----------------------------------------------------ISL-----
-------LARDN-----T-SKP-KY-----LDDGFKS-LSESSSS-------ITSE-RIH
RAEEASG

PF01490 // ENSGT00390000011245_0_Domain_1 (128, 700)

LSMMQTLIHLLKCSIGTGLLGLPLAMKNAGLLVGPVSLLAIGILTVHCMVI--
LLNCAH--HL-------SQR----------------------------------------
-----------------LQKTFVNYG--EAMMYSLQTCPNAWLRTH--SVWGSANIYFVF
SCILIVSSK---------HLTYPSCNSSLENVRNHSDCQTGE-AWGIFKMYTVSFLLIIT
QLGFCSVYFMFMADSLQQMVEEAHVTSKTCEPRK--ILVLTPNVDIRFYMLTILPFLILL
VFIQNLRVLSIFSTLANITTLGSMALIFQYIMQEI----PDPRNLPLM------------
ASWKTFLLFFGTAIFTFEGVGMV-L-----PLKNQMKHPQQFSFVLYLGMSLVI--VLYI
CLGTLGYMKFGSNTQASITLNLPNCWL--YQSVKLMYSIGIFFTYALQFHVPAEIIIPII
ISQVSESWALFADLSVRTAL--VCL----TCVSAILIPRLDLVISLVGSVSSSALALIIP
PFLELITFYPEDMN-CITIVKDIMISILGLLGCVFGTYQALYELTQPINHSV-ANSTGVY
A--------------------------

------------------------------------------------------------
-----------------MSTQRLRNEDYHDYSSTDVS-PEESPSEG-L-SHFS-SGSYQR
FGER-NS

PF01490 // ENSGT00390000011245_0_Domain_1 (128, 700)

TTSLQTLIHLLKGNIGTGLLGLPLAVKNAGILLGPLSLLVISIVAVHCMSI--
LVKCAH--HF-------CRR----------------------------------------
-----------------LNKPYMDYG--DTVMCGLEANPSAWIRSH--SHWGRHIVDFFL
II---------------------------------------------------------T
QLGFCCVYFVFLADNFKQVLEAANGTTNNCHHNET-V-ILTPTMDSRLYMLSFLPFLVLL
VFIRNLRALTIFSLLANVSMLVSLVMIYQFIVQRI----PDPSHLPLV------------
ASWKTYPLFFGTAIFSFESIGMV-L-----PLENKMKDPQKFPVLLFVGMAIVT--VLYI
SLGSLGYLQFGANIQGSLTLNLPNCWL--YQSVKLLYSFGIFFTYALQFYVPAEIIIPFF
VSRVPDRCHLLVDLFVRTML--VCL----TCVLAVLIPRLDLVISLVGSVSSSALALIIP
PLLEITTFCAEGLS-PLLIAKDVLISSLGFVGFVVGTYQALYELIQPNNAPISLNA--TH
ASV------------------------

--------------------------------------------------MPLTESVRGP
QETVSLKMDFMSSPESAK---KLQNKTSS-SLEG--S-PSESL-----------------
DLHKT

PF01490 // ENSGT00390000011245_0_Domain_1 (126, 630)

KGITGFQTLVHLVKGNMGTGILGLPLAIRNAGILLGPLSVLAMGFLSCHCMHI--
LVKCAR--HF-------CHR----------------------------------------
-----------------LNKPFMDYG--DTVMHGLESSPSSWLQNR--AYWGRNVVILFL
TV---------------------------------------------------------T
QLGICCAYIVFVADNLKQIVEAINSTATNCHHNET-V-MLTPTMDSRLYMLSFLPFLVLL
VLIQNLRVLSIFSLLANISMLVSLVIIIQYIAQGI----PDPGRLPLV------------
ASWKTYPLFFGTAIFSFESIGVI-L-----PLENNMKDARRFSAIVSLGMFIIT--TLYV
IVGALGYLKFGDDIKASITLNLPNCWL--YQSVKLLYIIGILCTYALQFYVPAEIFVPFI
LSRISKRRTWILDFAIRLIV--VCL----T------------------------------
------------------------------------------------------------
---------------------------

----------------------------------------------------MPL-----
-------LKKDD-----C-HKELSS-----LDGTPKS-PSKTSSS-------ATTE-SVR
PAPEA-ELTRMQTLIHLLKCNIGTGLLGLPLAIKNAGLLVGPISLLAIGVLTVHCMVI--
LLNCAE--HL-------SQR----------------------------------------
-----------------LHKTFVTYE--EATMYSLETCPHTWLRTH--AVWGSWGLTLLP
RLEG-SGTI---------MAHY-------SSGNPHASCLFSPCLLFCYP

PF01490 // ENSGT00390000011245_0_Domain_1 (350, 700)

RYTVSFLLIIT
QLGFCSVYFMFMADNLQQMVEEAHVTSNTCQLGK--TLVLTPILDIRFYMLTILPFLVLL
VFIQNLKVLSFFSTLANITTLGSTALIFEYIIQGI----PYPSDLPLM------------
ANWKTFLLFFGTAIFTFEGVGMV-L-----PLKNQMKHPQQFPFVLYLGMSVVI--SLYI
CLGTLGYMKFGPDTQASITLNLPNCWL--YQSVKLLYSIGIFFTYALQFHVPAEIIIPFA
VSQVSESWALSVDLSIRTAL--VCL----TCVSAILIPRLDLVISLVGSVSSSALALIIP
PLLEVTTFYSEDIS-CITIAKDIMISILGLLGCIFGTYQALYESTQPVNHAI-ANSTGVY
A--------------------------

--------------------------------------------------MPGTKSARGP
QGAVDLKLDLRSPLKSA------KNKDSG-FLDG--R-PSELP-----------------
VLEKT

PF01490 // ENSGT00390000011245_0_Domain_1 (126, 702)

NGITAFQALIHMVKCNMGTGILGLPLAVKNAGLLIGPLSLLAMGLITWHCMHI--
LVRCSQ--RF-------CHR----------------------------------------
-----------------LNKPFMDYG--DTVMHGLEASPNTWLRDH--AHWGRHMVSFFL
IF---------------------------------------------------------T
QMGFCCVYIVFLADNLKQVVEAVNSTSSNCHCNET-V-ILTPTIDSRLYMLAFLPILMLL
VLFRNLRVLSIFSMLANISMLVSLIIIAQYIAKDI----PDPSQLPLV------------
TSWKTYSLFFGTAIFSFESIGFV-L-----PLENKMKDSRRFPAILSLGMAIIT--ALYI
GFGVLGYLQFQNNIKASITLNLPNCWL--YQSVKLLYIAGILFSYALQFYVPAEIIIPSA
ISRVSKRWVLLLDLSIRFTM--VCL----TCILAILIPRLDLVLSLVGSVSSSALALIFP
PLLEITTYYSEGLS-PLTIAKDALISILGFVGFVVGTYQALDELIQPGHPVTFSNST---
IFIQ-----------------------

------------------------------------------------------------
-----------------MSTQRLRNEDYHDYSSTDVS-PEESPSEG-L-GNFS-PGSYQR
LGES-G

PF01490 // ENSGT00390000011245_0_Domain_1 (127, 699)

NMTWFQTLIHLLKGNIGTGLLGLPLAVKNAGLLMGSLSLLVIGIVAVHCMGI--
LVKCAR--HL-------CRR----------------------------------------
-----------------MNKPFLDYG--DTVMYGLESSPSAWIRSH--SHWGRHIVGFFL
VV---------------------------------------------------------T
QLGFCCVYFVFLAENFKQVIEAANGTTTNCQNNET-V-VLMPTMDSRLYMLSFLPFLVLL
TFIRSLRILSIFSLLANVSMLVSLITIYQFIVQRI----PDPHSLPLV------------
APWKTYPLFFGTAVFAFEGIGVV-L-----PLENKMKNSKKFPLILYLGMTIVT--VLYI
SLGSLGYLQFGATIKGSITLNLPNCWL--YQSVKLLYSIGIFFTYPLQFYVAAEIIIPII
VSRVPEHYMLMVDLCVRTAM--ACI----TCVLAVLIPRLDLVLSLVGSVSSSALALIIP
PLLEVATFYGEGLS-PLAIIKDALISIIGFLGFVVGTYESLCELIQPKHVDTSTNS--TS
AFI------------------------

--------------------------------------------------MSSTTNARGA
QGNDSLNLDFMSPSESAK---DLQ-KPSG-FLEG--S-PSESP-----------------
GLEKT

PF01490 // ENSGT00390000011245_0_Domain_1 (126, 702)

KGITGFQTLVHLVKGNMGTGVLGLPLAIKNAGILMGPLSVLVIGFVACHCMRL--
LVKCAR--HF-------CHR----------------------------------------
-----------------LNKPFMDYG--DTVLHGLESSPSLWLQKH--AHWGRDTVTLFL
IV---------------------------------------------------------T
QLGFCCVYIVFLADNLKQVVEAVNSTAVNCHSNET-A-TLTPTMDSRLYMLSFLPFLVLL
ALIRNLRVLTIFSMLANISMLISLVIITQYIAQGI----PDLHSLPLV------------
ESWETYPLFFGTAIFSFESIGVV-L-----PLENNMEDSRRFPAILYLGMSIIT--SLYI
IIGVLGYLKFGDDIKASITLNLPNCWL--YQSVKILYIIGILCTYSLQFYVPAGIIIPFV
HSRVSKRWALVTDVFIRFSL--VCL----TCLMAILIPRLDLVLSLVGSVSGSALALIIP
PLLEIITFYSEGMS-PLTITKDALISILGFVGFVAGTYLALNDLIEPKHPHSILNST---
MTTQ-----------------------

--------------------------------------------------MPLTKSVRGP
QGAVSLKMDFMSSPESAK---KLQDKTTS-FLEG--S-SSESL-----------------
RLQKT

PF01490 // ENSGT00390000011245_0_Domain_1 (126, 702)

KGITGFQTLVHLVKGNMGTGILGLPLATKNAGILMGPLSVLAMGFVACHCMHI--
LVRCAR--HF-------CHR----------------------------------------
-----------------LNKPFMDYG--DTVMHGLEASPSSWLQNH--AYWGRCVVIFFL
IV---------------------------------------------------------T
QLGFCCAYIVFVADNLKQIVEAINGTTNTCVHNGT-M-TLTPTMDSRLYMLSFLPFLVLL
ALIRNLRILSIFSLLANISMLVSLVIVVQYIVQGI----PDPSRLPLV------------
ASWNTYPLFFGTAVFAFESIGVV-L-----PLENNMKDTHRFPAIVSLGMFIIT--ALYI
IIGTLGYLQFGDDIKASITLNLPNCWL--YQLVKFLYIIGILCTYPLQFYIPAEIIIPFI
LSRVSKRWAQVLDLSIRLAM--VCL----TCSIAILIPHLDLVLSLVGSVSGSALAFVIP
PLLEITTYYSEGMS-PFTIAKDALISILGFVGFVAGTYQAIHELIQPEHTLTFPNST---
MFIH-----------------------

--------------------------------------------------MSSLK-----
-------LLARR-----TSFDDTDSE---DRLDSKKT-FSSCS--------LRSTD-SFR
WFRESESLTGLQALIHLFKANIGTGLLGLPLAIKNAGIIVGPLSLLVLGIMVIHCMGI--
LVKCAH--HF-------CHR----------------------------------------
-----------------MQRSFVDYG--DSVMYGMEASPFFWLQRH--STWARLHGKIIK
LLLGLMLHNQNRAIDLGYSSKLSSCIVGLAD-NQHGTCERD---VPMSLG

PF01490 // ENSGT00390000011245_0_Domain_1 (351, 701)

HLVRSLLIIT
QLGFCSVYFLFLADHFKQMAETSSI-SHSCKKNETTMMEIPPSLNLHLYMLTFLPFVILL
VFFHNILMLAIFSTVGDIAILAAVTLIFSYIIQDL----PNPKNLPWS------------
ANWQSYTLFFGSAIFSLEGIGVI-L-----PIENQMKFPGHYTVVLYMGMPIII--VLYI
TLGTLGYLKFGENVQANIILNLPNCWL--YQSIKLLYSVGIFFTYALQFYVPTKIIIPIV
ISCVPEQWELLVDLSVRALM--VCI----TYIVAMLIPHMELVIALLGSASCTALALIIP
PLLEICTYYLDGIS-SFTIIKDLLISSVGILGCIMGTYQSFYELIHLSFFSSPEDSTRAF
E--------------------------

------------------------------------------------------------
-----------------MSTQRLRNEDYHDYSSTDVS-PEESPSEG-L-NNFSSQGSYQR
FGES-

PF01490 // ENSGT00390000011245_0_Domain_1 (126, 702)

NSTTWFQTLIHLLKGNIGTGLLGLPLAVKNAGILIGPLSLLVMGIIAVHCMSI--
LVKCAH--HF-------CRR----------------------------------------
-----------------LNKPFVDYG--ETVMYGLESSPSSWLRNH--AHWGRHIVDFFL
IV---------------------------------------------------------T
QLGFCCVYFVFLADNFKQVIEAANGTTNNCHNNET-V-ILTPTMDSRLYMLSFLPFLVLL
VFVRNLRVLSIFSLLANITMLVSLVMLYQFIVQNI----PDPSGLPLV------------
APWKTYPLFFGTAIFAFEGIGMV-L-----PLENKMKDPQKFPLILYVGMAIVT--ALYI
SLGCLGYLQFGANIQGSITLNLPNCWL--YQSVKLLYSVGIFFTYALQFYVPAEIIIPFF
VSRVPEHWELVVDLSVRTML--VCL----TCILAILIPRLDLVISLVGSVSSSALALIIP
PLLEITTYYSEGMS-PLTIAKDALISILGFVGFVVGTYEALYELIQPSSAPIFINS--TG
AFV------------------------

--------------------------------------------------MPVTKSGRGH
QGAVDLKLDLTSSPKSAK---KLQSKDSS-FWDG--H-PSESP-----------------
GLEKTK

PF01490 // ENSGT00390000011245_0_Domain_1 (127, 700)

GITAFQTLVHLVKGNMGTGILGLPLAVKNAGILMGPLSLLAMGFTACHCMHI--
LVRCAQ--HF-------CHR----------------------------------------
-----------------LNKPFMDYG--DTVKHGLEASPSAWLRNH--AHWGRRIVSFFL
IV---------------------------------------------------------T
QLGFCCVYIVFLADNLKQVVEAVNGTTTNCHYNET-V-ILTPTMDSRLYMLSFLPFLVLL
VLIRNLRVLTIFSMLANISMLVSLIIITQYIAQGI----PDPSRLPLV------------
ASWKTYPLFFGTAIFSFESIGVV-L-----PLENKMKDARRFPAILSLGMSIIT--ALYI
GIGSLGYLRFGNDIKASITLNLPNCWL--YQSVKLLYVVGILCTYALQFFVPAEIIIPFA
TSQVSKRWALPLDLSIRLAM--VCL----TCTLAILIPRLDLVLSLVGSVSSSALALIIP
PLLEITTYYSEGMS-PLTIAKDLLISILGFVGFVVGTYQALDELIFSGHPLTSSNST---
IFVQ-----------------------

--------------------------------------------------MSVTKKARAR
QEAATLTLDLMPSPQSTK---KLQDQESS-VLNR--S-ASERS-----------------
GLEETKG

PF01490 // ENSGT00390000011245_0_Domain_1 (128, 700)

ITGFQTLVHLVKGNMGTGILGLPLAVKNAGILMGPLSLLVMGFVACHCMHI--
LVRCAR--RF-------CCR----------------------------------------
-----------------LNKPFMDYG--ETVMHALEASPSTWLRSH--AAWGRHIVGFFL
IV---------------------------------------------------------T
QLGFCSVYIVFLADNLKQVIEAVNGTSNNCSSNQT-V-TPMPTMDSRLYMLTFLPFLALL
VFIRNLRVLTIFSLLANLSMLVSLVIIAQYIAQGI----PDPSQLPLV------------
ASWKTYPLFFGTAIFSFESIGVV-L-----PLENKMKDARHFPAILSLGMSIVT--TLYI
AIGALGYLRFGDDIKASITLNLPNCWL--YQSVKLLYILGILCTYALQFYVPAEIIIPFA
ISQVSERWALPVDLSTRLAM--VCL----TCVLAVLIPRLDLVLSLVGSMSSSALALIIP
PLLEVTTYSSRGLG-PLTLAKDAIISVLGFVGFVVGTYQALDELIESGVSLPASNST---
LFVQ-----------------------

--------------------------------------------------MPGTKNAASH
QEAATFTLDLVPSPQSTK---KLQNKDSS-LLDG--S-SSGSS-----------------
GLEKAKG

PF01490 // ENSGT00390000011245_0_Domain_1 (128, 700)

ITGFQTLVHLVKGNMGTGILGLPLAVKNAGILMGPLSLLAMGFVACHCMHI--
LVRCAQ--RF-------CRR----------------------------------------
-----------------LNKPFMDYG--ETVMHALEASPSTWLQNH--ARWGRHVVSFFL
II---------------------------------------------------------T
QLGFCCVYIVFLADNLKQVIEAVNGTTNNCRSNET-V-TLTPTMDSRLYMLAFLPFLWLL
VLLRNLRVLTIFSLLANISMLVSLVIITQYIAQGI----PDPSRLPLV------------
ASWKTYPLFFGTAIFSFESIGVV-L-----PLENKMKDARRFPAILSLGMSIIT--TLYI
GIGALGYLRFGEDIRASITLNLPNCWL--YQSVKLLYIIGILCTYALQFYVPAEIILPWA
ISRVSERWALPVDLSIRLTM--VCL----TCVLAVLVPRLDLVLSLVGSVSGSALALIIP
PLLEVTTYSSEGLS-PLTLAKDTLISILGFVGFVAGTYQALDELIESGDSLPPSNAT---
LPIQ-----------------------

--------------------------------------------------MPVTQSARGS
QEAATLKLDPISPCNGPK---KPHNKDSR-FLDG--S-SLESP-----------------
GVEKTK

PF01490 // ENSGT00390000011245_0_Domain_1 (127, 700)

GITALQTLVHLLKGNMGTGVLGLPLAVKNAGVLMGPLSLLVMGLVACHCMHI--
LVRCAQ--RF-------CHR----------------------------------------
-----------------LNKPFMDYG--DTVMHALGASPSVWLRNH--AHWGRYTVSFLL
VV---------------------------------------------------------T
QLGFCCVYIVFLADNLKQVVEAVNSTAVSCHGNET-A-LAMATMDSRLYMLAFLPGLALL
VFIRNLRVLTVFSLLANISMLVSLVIITQYISQGI----PDPSQLPLV------------
ASWKTYPLFFGTAIFSFESIGVV-L-----PLENKMKDSRRFPAILSLGMSIIT--ALYI
GIGALGYLRFGDDIKASITLNLPNCWL--YQSVKLLYVVGILCTYALQFYVPAEIMIPFA
VARVSKCWALPVDLSIRLAM--VCL----TCILAILIPRLDLVLSLVGSVSSSALALIIP
PLLEVATYYTEGMS-PLTIAKDALISALGFVGFVVGTYQALGELIGSGDSPPSSNST---
IFLQ-----------------------

--------------------------------------------------MSMAKSARDP
QEAVDLNLDLRSPPESAN---KLPNTDSS-FLDG--S-PSESP-----------------
SLETTK

PF01490 // ENSGT00390000011245_0_Domain_1 (127, 700)

GITAFQTLVHLVKGNIGTGVLGLPLAMRNAGILMGPLGLLAMGLISCHCMHI--
LIRCAR--RF-------CHR----------------------------------------
-----------------FNKPFMDYG--DTVMHGLEANPSAWLRNH--AHWGRYIVSFFL
IV---------------------------------------------------------T
QMGFCCVYIVFLADNLKQVVEAVNSTTNNCHSE-T-V-ILTPTMDSRLYMLTFLPFLVLI
VLIRNLRVLTIFSLLANITMLISLIIIVQYIVQEI----PDPRQLPLV------------
ANWKTYSLFFGTAIFSFESIGVV-L-----PLENKMKDARRFPVILSLGMSIIT--ALYV
SVGTLGYLRFGDDVKASITLNLPNCWL--YQSVKILYIIGILCTYALQFYVPAEIIVPLA
TSHVSKRWALPLDLFIRLAM--VSL----TCILAILIPRLDLVLSLVGSLSGSALALIIP
PLLEITTYYSEGLS-PVTIVKDTLISILGFVGFVMGTYQALDELIQSGDSLTFSNST---
VFIQ-----------------------

--------------------------------------------------MSVTK---ST
EGAVAVKLDLMSPPESAK---KLENKDST-FLDE--S-PSESP-----------------
GLKKTK

PF01490 // ENSGT00390000011245_0_Domain_1 (127, 203)

GITVIQALIHLVKGNMGTGILGLSLAVKNAGILMGPLSLLVMGLIACHCMHI--
LVRCAQ--RF-------CKRRSQSGHCAYLVGSSGNWAQTVQRMVMRSQWDHGYENYHPH
ARCALDSCCVVPASFNRLNKPFMDYG--DTVMHGLEASPSAWLQNH--AHWGRHIVSFFL
IV---------------------------------------------------------T
QLGFCCVYIVFLADNLKQVVEAVNSTTNNCHSNET-V-MLTPTMDSRLYMLSFLPFLVLL
VLIRNLRILTIFSMLANISMLVSLVIITQYITQEI----PDPSRLPLV------------
ASWKTYPLFFGTAIFSFESIGVV-L-----PLENKMKNARHFPAILSLGMSIVT--SLYI
SIGTLGYLRFGDDIKASISLNLPNCWL--YQSVKLLYIAGILCTYALQFYVPAEIIIPFA
ISRVSTRWALPLDLSIRLAM--VCL----TCLLAVLIPRLDLVISLVGSVSSSALALIIP
PLLEVSTFYSEGMS-PLTIFKDALISILGFVGFVVGTYQALDELLKSGDSPLFSNST---
TFLR-----------------------

--------------------------------------------------MVKSS-----
-------LLRKD------GNRERNL-----FGVSKAP-SKSSSSS--NGSSSNVSP-QKD
PQGEADALLF

PF01490 // ENSGT00390000011245_0_Domain_1 (131, 700)

MQIFIHLLKSNIGTGFLGLPLAVKNAGLLVGPISLLAIGILTVHCMDI--
LLKCAS--HL-------TQR----------------------------------------
-----------------LQRSFVNYE--ETTMYSLETCPNPWLRTH--SVWGRY------
---------------------------------------------------IVSFLLIIT
QLGFCSVYFMFMADNLQQIVEEAHFTSNVCQPRT--SLVMTPVLDARFYMLTILPFLILL
VLVQNSQVLSIFSTLATITTLGSLALIFEYLIQ-I----PRHSSLPLV------------
ASWKTFLLFFGTAIFTFEGVGMV-L-----PLKSQMKSPQQFPAVLYLGMSFVI--FLYI
CLGTLGYMKFGSDTQASITLNLPNCWL--YQSVKVMYSVGIFFTYALQFHVPAEIIIPYV
ISRVSENWALFVDLTVRTAL--VCV----TCFSAVLIPRLDLVISLVGSVSSSALALIIP
PLLEIATFYSENIS-CVTIVKDIMISILGLLGCVFGTYQALYEMTQQARFPM-ANSTSGY
T--------------------------

--------------------------------------------------MLKTS-----
-------LLGKD-----F-NSAPSN-----LDDGSKS-LLESRSG-------VASQ-NVY
PAEEANG

PF01490 // ENSGT00390000011245_0_Domain_1 (128, 694)

LSIMQTLIHLLKCNIGTGLLGLPLAMKNAGLLVGPISLLAIGILTVHCMVI--
LLNCAH--HL-------GQR----------------------------------------
-----------------LQKTFVNYG--EAMMYSLETCPNAWLRTH--SVWGR-------
--------------------------------------------------YTVSFLLITT
QLGFCSVYFMFMADNLQQMVEEVHMTSSNCQPRK--TLVPTPILNIRFYMLTILPFLVLL
VFIQNLRLLSIFSMLANITTLGSMALIFEYIIQEI----PDPSSLPLM------------
ASWKTFLLFFGTAIFTFEGVGMV-L-----PLKNQMKHPQQFSFVLYLGMSLII--ILYI
CLGTLGYMKFGSNTQASITLNLPNCWL--YQSVKLMYSIGIFFTYALQFHVPAEIIIPFI
ISQVSESWTLLIDLSVRTAL--VCL----TCVSAILIPRLDLVISFVGSVSSSALALIIP
PLLELITFYAEDMS-CATIAKDVMIGILGLLGAFSC------------------------
---------------------------

----------------------------------------------------MSL-----
-------LRRD----------FHSS-----LDDGSKS-LLERNSN-------VTAE-NVH
PAEEASGL

PF01490 // ENSGT00390000011245_0_Domain_1 (129, 700)

SRMQTLIHLLKCNIGTGLLGLPLAMKNAGLLVGPISLLGIGVLTVHCMVI--
LLNCAH--HL-------SQR----------------------------------------
-----------------WQKTFVNYG--EAMMYSLETCPNAWLRTH--SAWGR-------
--------------------------------------------------YTVSFLLITT
QLGFCSVYFMFMADNLQQMVEEAHMTSNNCQPRK--FLVLAPILDIRFYMLTILPFLMLL
VFIQNLKLLSIFSSLANITTLGSMALIFEYIVQEI----PDPSNLPLM------------
ASWKTFLLFFGTAIFTFEGVGMV-L-----PLKNQMRDPQQFPFVLYLGMSLVI--TLYI
CLGTLGYMKFGSSTQASITLNLPNCWP--YQSVKLLYSIGIFFTYALQFHVPADIILPFA
VSQVSERWTLFVDLSVRIAL--VCL----TCVSAILIPRLDLVISFVGSVSSSALALIIP
PLLELITFYPEDMS-CATIAKDIMISILGLLGCVFGTYQALYELIQPIGHSV-ANATGEM
DLTQVSTHTPQGMPFLVWDCFGGLLYL

--------------------------------------------------MSVTKSAGDP
QVATTIKLDLVSSPESTK---KVQSQDPS-LGNG--S-ASDP------------------
-SKKTKG

PF01490 // ENSGT00390000011245_0_Domain_1 (128, 700)

ITGFQTLVHLVKGNMGTGILGLPLAVKNAGILMGPLSLLVMGLIACHCMHI--
LVRCAQ--RF-------CHR----------------------------------------
-----------------LNKPFMDYG--DTVMHGLEASPNAWLQNH--AHWGRYIVIFFL
IV---------------------------------------------------------T
QLGFCCVYIVFLADNLKQVVEAVNGTTISCHYNET-I-DLTPTMDSRLYMLAFLPILGLL
VFIRNLRILTIFSMLANISMFVSLVIIAQYIIQGI----PDPSQLPLV------------
ASWKTYPLFFGTAIFSFESIGVV-L-----PLENQMKDARRFPTILSLGMSIIT--TLYI
AIGTLGYLRFGDDIKASITLNLPNCWL--YQSVKLLYVVGILCTYALQFYVPAEIIVPLA
VSQVSKRWKLPVDLSIRLAM--VCL----TCMLAILIPRLDLVISLVGSVSSSALALIIP
PLLEIATYYSESIS-PLTITKDALISILGFVGFVVGTYQALDELIGSGNSLPFSNST---
MFIQ-----------------------

------------------------------------------------------------
-----------------MSTQRLRDEDYHDYSSTDVS-PEESPSEG-L-SNFSSPGSYQR
FGES-S

PF01490 // ENSGT00390000011245_0_Domain_1 (127, 700)

GTTWFQTLIHLLKGNIGTGLLGLPLAVKNAGILMGPLSLLVIGIVAVHCMGI--
LVKCAH--HF-------CHR----------------------------------------
-----------------LNKPFVDYG--DTVMYGLESSPSSWLRNH--ARWGRHIVDFFL
IV---------------------------------------------------------T
QLGFCCVYFVFLADNFKQVIEAANGTTNDCHNNET-V-ILTPTMDSRLYMLTFLPFLVLL
VFVRNLRALSIFSLLANVTMLVSLVMIYQFIVQRI----PNPSHLPLV------------
ASWNTYPLFFGTAIFAFEGIGVV-L-----PLENKMKNPQRFPVILYVGMAIIT--ALYI
SLGCLGYLQFGAHIQGSITLNLPNCWL--YQSVKLLYSIGIFFTYALQFYVAAEIIVPFF
VSRAPERCELVVDLFIRTVL--VCL----TCILAILIPRLDLVISLVGSVSSSALALIIP
PLLEITTYYSEGLS-PLTVAKDALISILGFAGFVVGTYQALYELSQPSTAPIFINS--TG
AFV------------------------

--------------------------------------------------MSVTKSTEGP
QGAVAIKLDIMSPPESAK---KLENKDST-FLDE--S-PSESP-----------------
GSKKTKG

PF01490 // ENSGT00390000011245_0_Domain_1 (128, 700)

ITGFQALVHLVKGNMGTGILGLPLAVKNAGILMGPLSLLVMGFVACHCMHI--
LVKCAQ--RF-------CKR----------------------------------------
-----------------LNKPFMDYG--DTVMHGLEANPSTWLQNH--AHWGRHIVSFFL
IV---------------------------------------------------------T
QLGFCCVYIVFLADNLKQVVEAVNSTTNNCNSNET-V-ILTPTMDSRLYMLSFLPFLVLL
VLIRNLRILTIFSMLANISMLVSLVIITQYITQEI----PDPSRLPLV------------
ASWKTYPLFFGTAIFSFESIGVV------LPLENKMKDARHFPAILSLGISIVT--ALYI
GIGTLGYLRFGDDIKASISLNLPNCWL--YQSVKLLYVAGILCTYALQFYVPAEIIIPFA
ISRVSTRWALPLDLSIRIAM--VCL----TCLLAILIPRLDLVLSLVGSVSSSALALIIP
PLLEVTTFYSEGMN-PLTIFKDALISILGFVGFVVGTYQALDELLKSADSLPFSNST---
TFIQ-----------------------

--------------------------------------------------MSVPKSAGAP
QGAVTLKLDSMSTPESAR---KLQNKDSR-FLDG--S-PSESP-----------------
DLEKTK

PF01490 // ENSGT00390000011245_0_Domain_1 (127, 700)

GITLFQTLVHLLKGNMGTGILGLPLAVKNAGILVGPLSLLVMGLVACHCMLI--
LVRCAQ--RF-------CQR----------------------------------------
-----------------LNKPFLDYG--DTVMHGLEASPSTWLQNH--AHWGRRIVSFFL
IV---------------------------------------------------------T
QLGFCCVYIVFLADNLKQVAEAINSTTNNCHNNET-V-IPTPTMDSRLYMLAFLPVLVLL
VFIRNLRVLTIFSMLANISMLVSLVIIAQYIAQDI----PDPSQLPLL------------
ASWTTYPLFFGTAIFSFESIGVV-L-----PLENKMEDARHFPIILSLGMSIIT--ALYT
SIGALGYLRFGDDIKASITLNLPNCWL--YQSVKLLYIIGILCTYALQFYVPAEIIIPFA
LSQVPKRWALPLDLSIRLAL--ACL----TCILAILVPRLDLVLSLVGSVSSSALALIIP
PLLEIATYYSEGMS-PLTIAKDALISILGFVGFVAGTYQALYELIESEESLPFSNST---
TFVQ-----------------------

-----------------------------------------------------MS-----
-------FLGRD-----Y-SSELDA-----LGHGSKS-LSESSSSS-TTS-----E-SDR
PA-EEAGL

PF01490 // ENSGT00390000011245_0_Domain_1 (129, 701)

SLPQTLIHLLKCNIGTGLLGLPLAIKNAGLLVGPISMLAIGVLTVHCMVI--
LLNCSQ--HL-------SQK----------------------------------------
-----------------LQKTFVNYG--EATMYSLEASTNTWLRTH--SVWGRY------
---------------------------------------------------TVSFLLIIT
QLGFCSVYFMFMADNLQQMVEEAHVTTNNCQPRK--SLLLTPILDIRVYMLTILPFLVLL
VFIQNLKVLAFFSTLANITTLGSMALIFEYIIQRI----PYPSDLPLM------------
ANWKTFLLFFGTAIFTFEGVGMV-L-----PLKNQMKDPQQFSFVLYLGMSLVI--SLYI
CLGTLGYMKFGSDTQASITLNLPNCWL--YQSVKLMYSIGIFFTYALQFHVPAEIIIPFA
ISQVSENWALFVDLSVRTGL--VCL----TCVSAILIPRLDLVISLVGSVSSSALALIIP
PLLEIITFYSEDMS-CVTIAKDIMISIMGLLGCIFGTYQAIYDLTQPVNLSM-ANSTGVY
S--------------------------

------------------------------------------------------------
------------------------------------------------------------
---------L

PF01490 // ENSGT00390000011245_0_Domain_1 (131, 700)

MQTLIHLLKSNIGTGLLGLPLAMKNAGLLVGPISLLAIGVLTVHCMVI--
LLNCTH--HV-------TQR----------------------------------------
-----------------LQKTFVNYG--EAMMYSLESCPSPWLRTH--SMWGRY------
---------------------------------------------------TVSFMLIVT
QLGFCSVYFMFMADNLQQIVEEAPTTSNTCQPRQ--ILVLGPILDIRFYMLSILPFLVLM
VLIQNLRVLSIFSTLASVTTLGSMALIFEYIIQ-I----PHPGNLPLV------------
ANWKTFLLFFGAAIFAFEGVGMV-L-----PLKNQMKNPQKFSFVLYLGMSLVI--SLYI
CLGTLGYMKFGSDTRASITLNLPNCWL--YQSVKLMYSVGIFFTYVLQFHVPAEIIIPFA
LSHVSESWALFVDLTVRTAL--VCL----TCVLAVLIPRLDLVISLVGSVSSSALALIIP
PLLEITTFYSEDIS-FVTIAKDVLISILGLLGCIFGTYQALYELTQHNFYSR-VNFTGGI
HV-------------------------

--------------------------------------------------MPVTENARGP
QEAPAFTLDHMSPPQSTK---NLQSKDSK-CLNG--N-SPEPS-----------------
AVENPKG

PF01490 // ENSGT00390000011245_0_Domain_1 (128, 700)

ITGFQTLVHLVKGNMGTGILGLPLAVKNAGILLGPLSLLVMGFVACHCMHI--
LVTCAR--HF-------CHR----------------------------------------
-----------------FNKPFMDYG--DTVMHGLEASPSAWLQSH--AHWGRNLVSFFL
IV---------------------------------------------------------T
QLGFCCVYIVFLADNLKQVVEAMNSTTNDCGYNET-V-ILSPSMDSRLYMLSFLPFLVLL
VFIRNLRALTIFSLLANVSMLVSLVIITQYIAQRI----PDPRPLPLA------------
ASWQTYPLFFGTAIFSFESIGVV-L-----PLENKMADARRFPAILSLGLSIVT--ALYI
GIGALGYLRFGEEIKASITLNLPNCWL--YQWVKLLYNVGILCTYALQFYVPVEIIIPLA
LSRVPERWALPVDLLVRLVL--VCL----TCVLAVLIPRLDLVISLVGSVSSSALALIIP
PLLEITTFCAEGLS-PLLIAKDVLISSLGFVGFVVGTYQALDELIGSRGSLSFPNST---
IVTQ-----------------------

------------------------------------------------------------
-----------------MSTQRLRNEDYHDYSSTDVS-PEESPSEG-L-SNPSSPGSYQR
FGES-N

PF01490 // ENSGT00390000011245_0_Domain_1 (127, 699)

STTWFQTLIHLLKGNIGTGLLGLPLAVKNAGILMGPLSLLVIGIVAVHCMGI--
LVKCAH--HF-------CHR----------------------------------------
-----------------LNKSFVDYG--DTVMYGLESSPCSCLRNH--AHWGRHIVDFFL
IV---------------------------------------------------------T
QLGFCCVYFVFLADNFKQVIEAANGTTNNCHSNET-V-IATPTMDSRLYMLSFLPFLVLL
VFVRNLRALSIFSLLANISMLVSLVMIFQFIVQGI----PDPSHLPLV------------
APWKTYPLFFGTAIFAFEGIGMV-L-----PLENKMKDPQKFPLILYVGMVIVT--ALYI
SLGCLGYLQFGSSIKGSITLNLPNCWL--YQSVKLLYSIGIFFTYALQFYVPAEIIIPFF
VSRVPEHCELVVDLFVRTVL--VCL----TCILAILIPRLDLVISLVGSVSSSALALIIP
PLLEIATYYSEGMS-PLTIAKDALISILGFVGFVVGTYEALSELVQPSNAPILVNS--TR
AFV------------------------

--------------------------------------------------MGKTP-----
-------LLREV------GKCERNI-----FGWSKAS-SKASS----SSNSNSASP-KKD
PRREADALMF

PF01490 // ENSGT00390000011245_0_Domain_1 (131, 700)

IQIFIHLLKSNIGTGFLGLPLAVKNAGLLVGPVSLLAIGVLTVHCMDI--
LLNCAC--HL-------TQR----------------------------------------
-----------------LQRSFVNYE--ETTMYSLETCPSSWLRTH--SVWGRY------
---------------------------------------------------IVSFLLIIT
QLGFCSVYFMFMADNLQQIVEEAHFTSNVCQPRQ--SLVMTSILDTRFYMLTILPFLILL
VLIQNPQVLSIFSTLATITTLSSLALIFEYLIQ-T----PHHSNLPLV------------
ANWKTFLLFFGTAIFTFEGVGMV-L-----PLKSQMKSPKQFPAVLYLGMSFVI--FLYI
FLGTLGYMKFGTDTQASITLNLPICWL--YQSVKLMYSVGIFFTYALQFHVPAEIIVPYV
ISRVSENWALFIDLTVRTAL--VCL----TCFSAVLIPRLDLVISLVGSVSSSALALIIP
PLLEITTFYSENIS-CATIVKDIMISILGLLGCVLGTYQALYEMTQQTHFYM-ANSTRVH
I--------------------------