Query Results 

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MFWK
FDLNTTSHVDKLLDKEHVTLQELMDEDDILQECKAQNQKLL-DFLCRQQCMEE---LVSL
ITQDPPLDMEEKVRFKYPNTACELLTCDVPQISDR-LGGDESLLSLLYDFLDHEPPLNPL
LASF--FSKTI

PF04499 // ENSGT00390000009899_2_Domain_0 (312, 569)

GNLIARKTEQVITFLKKKDKFISLVLKHIGTSALMDLLLRLVSCVEPAG
LRQEVLHVS-----------LGVPPVPEGRGSNASQTLCDIVRLGRDQGSQLQEAL-EPD
PLLT-ALESQDCVEQLLKNMFDGDRTESCLVSGTQVLLTLLETRRVG-------------
------TEGLVDSFSQGLERS-YTVSSSVLHGIEPRLKDFHQLLLNPPKKKAILTTIGVL
EEPLGNARLHGARLMAALLHTNTPSINQ

ENSGT00390000009899_2_Linker_0_6 (569, 569)

PF04499 // ENSGT00390000009899_2_Domain_6 (569, 719)

ELCRLNTMDLLLDLFFKYTWNNFLHFQVELCI
AAILSHAAREDRTEASGSESRA--EPLHENG---NRSLETPQP-PTSLPDNTMVTHLFQK
CCLVQRILEAWEANDHTQAAGGMRRGNMGHLTRIANAVVQNLERGPVQTHISE--VIRG-
--DCRLRLPSARQQVLTALTVRDPV-AVSTHHLHSSSEDEDIEGAFPNELSLQQ-AFSDY
QIQQMAASFVDQFGFNDEEFADQDDNINAPFDRIAEINFNIDADE--DSPSAALFEACCS
DRIQPFDD-----------DEDEDIWEDSDTRCATRVMARARFGAPHASESCSKNGPERG
GQDGKASSEAHGD-----------APGAGAPPAPGKKAAP-PVEGDSE-GAMWTAVFEEP
ANST--PTAPGVCVWVGC--WQEAA----ACERPHVWGPYGQ---------G---GR---
----------ASWPLLPHWTA-QASSFAVSPASPCAWNVCVTRKAPLLASNSSSSVGSDS
EDDYQ-----KAASAVDAVSRGPGREAPPLPTVAR-TEEA----------------VGRA
ECP-DSRLLDPAC--PAPKEVTAAPAV--A-----AVAITTALSKAGPAIPTPAVSSAVA
VAVPLGPIMAVTTAPA--------MVATLGTVTKDRKTDAP-PEGAALNGPV

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MFWK
FDLNTTSHVDKLLDKEDVTLRELMDEDDILQECKAQNRKLL-DFLCRQQCMEE---LVSL
VTRDPPLDMEEKVRFXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---XXXXXXXXX
XXXXXXXXXXXXXXXXXXX

PF04499 // ENSGT00390000009899_2_Domain_4 (320, 872)

XXVIMFLKKKEQFISLVLKHIGTSALMDLLLRLVSCVEPVG
LRQEVLLWLNEEKIIQRLVELIHPSQDEDRQSNASQTLCDIVRLGREQGSQLPEAP-EPD
PLLT-VLESQDCVEQLLKNMFDGDQTESCLVSGTQVLLTLLETRRAGT------------
-------EGLVDSFSQGLERL-CTVSASILHGIEPRLKDFHQLLLNPPKKTAILTTIGVL
EEPLGNARLHGARLMAALLHTNTPSINQELCRLNTMGLLLDLFFKYTWNNFLHFQVELCI
AAILSHAAQEDKAEASAPMSGV--EPQPASGD-----PEAPQP-AATCPKNTMVTHLFQQ
CCLVQRILEAWEANDHTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXX-X-XXXXXXXXXXXXXXXXXXXXXXX-XXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXAPFDRIAEINFNIDAEE--DSPNAALFEACCS
DHIQPFDDE------------EDDIWEDKDT

PF04499 // ENSGT00390000009899_2_Domain_6 (320, 872)

XXVIMFLKKKEQFISLVLKHIGTSALMDLLLRLVSCVEPVGLRQEVLLWLNEEKIIQRLVELIHPSQDEDRQSNASQTLCDIVRLGREQGSQLPEAP-EPDPLLT-VLESQDCVEQLLKNMFDGDQTESCLVSGTQVLLTLLETRRAGT-------------------EGLVDSFSQGLERL-CTVSASILHGIEPRLKDFHQLLLNPPKKTAILTTIGVLEEPLGNARLHGARLMAALLHTNTPSINQELCRLNTMGLLLDLFFKYTWNNFLHFQVELCIAAILSHAAQEDKAEASAPMSGV--EPQPASGD-----PEAPQP-AATCPKNTMVTHLFQQCCLVQRILEAWEANDHTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-X-XXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXAPFDRIAEINFNIDAEE--DSPNAALFEACCSDHIQPFDDE------------EDDIWEDKDTHCTTRLTARARFGAPHASESCLKNGLDRS
CQERKDSAAGGD------------VALAGAPGTPSQES---PAEN-SSEGVTWA-VFDEP
VNSM--APAPSVAMDVGSSVWAASAP-STLAPEEKGWAKFTDFQPFCCSESG---PRCSS
PVDEGY--TQGGPNQGPERPL-PGSCRAVSPASPCAWNVCVSRKAPLEASSSD-------
-EDEQ-----KVAGASEAISMGPSQEGPPLPTAAA-E-----------------------
-CT-TRRPPDPTG--PAPTEAASLLAM--AVSTDATLAATAALSKVSPAPATPTT-----
---FPGPTAAVTTTA-ATASPAISTVATLGTVAKDR----------------

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MFWK
FDLNTTSHVDKLLDKEDVTLRELMDEDDILQECKAQNRKLL-DFICQQHCMEE---LVNL
ITHEPPIDMDEKVRFKYPNTACELLTSDVPQINDR-LGGDETLLNILYDFLDHKPPLNPL
LASF--FSKTI

PF04499 // ENSGT00390000009899_2_Domain_0 (312, 565)

GNLIARKTEQVIGFLRKKDQFISLVLKHIDTSAMMDLLLRLISCVEPAP
LRQEVLNWLNEAKVIQRLVELIHSSQDEDRQSNASQTLCDIIRLSRDQGSQLQEIS-EPD
PLLT-ALESKECVEQLLKNMFDGDQTENCIVNGTQILLTLLETRRSGV------------
-------EGLVDSFSQGFERS-YTVNSSILNGIEPRLKDFHQLLLNPPKKMSILTTIGVL
EEPLGNARLHGARLIAALLHTNTP

ENSGT00390000009899_2_Linker_0_6 (565, 566)

S

PF04499 // ENSGT00390000009899_2_Domain_6 (566, 744)

INYELCRLNTLDLLLDLFFKYTWNNFLHFQVELCI
AAVLSHSVHEGKSVMNDLEN-------KEEVLNGNVTTENL-KTLDQGPENVMVTHLFQK
CCLLQRILDAWEANDKIQAEGGMRRGNMGHLTRIANAVVQNVEKGPMQTQIGE--FIKEL
PEDCRGRWESFVEETLRETNRKNTVDLVSTHHLHSSSEDEDIESSFPNELSLQQ-AFAEY
QIQQMTANFVDQFGFNDEEFADQDDNINAPFDRIAEINFSIDADD--DSSNASLFEACCN
ERIQQFDDK----------EEEEDIWEEKEITYATQVKSRTRFGVSQTSESSSKSDLENG
DHDGSVDSEEEET--DEHT-----TPP-TENTNKNNPSE--QKDSDATEGSGWTAVF-EP
VNSK--PPAPCVAMDVGSSVWDSAAP-ETATPEEKGWAKFTDFQPFCCSESG---PRCSS
PVDTESSDSEGNPKQSQDKTF-------S-AASPCVWNVCVARKAPLVASDSSSSGGSDS
EEE------DKADIVTETISTGSGQETIKLTMDAK-NEKAVFTSDA-DCLVIDKLTITDM
GTAKASKPLNSVS---QHSEE---------------------------------------
----------------RQHTAAG-GAATTESTTKDRKEEVLPCAEATLNGPA

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MFWK
FDLNTTSHVDKLLDKEDVTLHELMDEDDILQECKAQNRKLLKTFLCRPQCMEE---LVSX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---XXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXX

PF04499 // ENSGT00390000009899_2_Domain_0 (320, 745)

XXVLVFLKKKEQFISLVLKHLGTSALMDLLLRLVSCVEPAT
LRQGVLHWLNEERIIQRLVGLIHPSQDEDRQSNASQTLCDIIRLGREQGSQLPEAP-EPD
PLLT-VLESQDCVEQLLKNMFDGERTESCLVSGTQVLLSLLDTRRAGA------------
-------DGLLDCFPQGLERPSGTVSGGVLHGIEPRLKDFHQLLLSPPKKSAILTTIGVL
EEPLGNARLHGARLMAALLHTDTPSIHRELCRLNTMGLLLDLFFKYSWNNFLHFQVELCV
AAILSRTAPDSRVEAAGPNGVAE-------------LPETPQPVASHPEEHTMVTHLFEQ
CCLVQRILEAWEANDHTQAAGGRRCGNMGHLTRIANAVAQSLERGPVQGHVSE--AIRXX
XXXXXXX-XXXXXXXXLTTNRRNAVDV-STPHSHPLSEDEDMEGAFPNELSLQQ-AFSEYQLQQMTATFVDQFGFNDEEFADQDDSVNAPFDRIAEINFHIDADE--

PF04499 // ENSGT00390000009899_2_Domain_4 (320, 745)

XXVLVFLKKKEQFISLVLKHLGTSALMDLLLRLVSCVEPATLRQGVLHWLNEERIIQRLVGLIHPSQDEDRQSNASQTLCDIIRLGREQGSQLPEAP-EPDPLLT-VLESQDCVEQLLKNMFDGERTESCLVSGTQVLLSLLDTRRAGA-------------------DGLLDCFPQGLERPSGTVSGGVLHGIEPRLKDFHQLLLSPPKKSAILTTIGVLEEPLGNARLHGARLMAALLHTDTPSIHRELCRLNTMGLLLDLFFKYSWNNFLHFQVELCVAAILSRTAPDSRVEAAGPNGVAE-------------LPETPQPVASHPEEHTMVTHLFEQCCLVQRILEAWEANDHTQAAGGRRCGNMGHLTRIANAVAQSLERGPVQGHVSE--AIRXXXXXXXXX-XXXXXXXXLTTNRRNAVDV-STPHSHPLSEDEDMEGAFPNELSLQQ-AFSEY
QLQQMTATFVDQFGFNDEEFADQDDSVNAPFDRIAEINFHIDADE--DTPSAALFEACCG
DHIQPFDDD------------EDDIWEDKDAHCTARVTARARFGAPHASESCPRNGPEHG
GRDRKEGADAGTP------------------PPP--AEGS-RT-QNSSEGAIWA-ASEEP
GNAA--APASGVAMDVGSSVWAAGTP-SASAPEEKGWATFTDFQPFCCSEAG---PRCSS
PVGTGSVDVQGGLKQGPESTS---PHLTAGPAAPCAWNACVTMTAPPVAPASD-------
-QSE------QVAGASEAVSVGPSREAPPLPSALP-RTE---------------------
-CA-TSRSPDLTS--AAPEETTSIPVV--AASPETPTAAATAMSKAGLGSTP--------
AAVPPAPVL--------GATPATATGAAQGTVTKDGKLDGTPPAGAALKGPV

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MFWK
FDLNTTSHVDKLLDKEDVTLHELMDEDDILQECKAQNRKLV-DFLCKQQCMEE---LVSL
ITHDPPLDMEEKVRFKYPNTACELLTSDVPQINDK-LGGDESLLNILYDFLDHEPPLNPL
LASF--FSKTIGNLIARKTEQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX

PF04499 // ENSGT00390000009899_2_Domain_0 (358, 745)

XXX
XXXXXXXWLNEENIIERLVELIHSSQDEDXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXX
XXXX-XXX-------XXXXXXXXXX----XXX--------XXXXXXXXXXXXXXXXXXXX
XXXXXXVEGLTDSFSQGLERS-YTVNSSILHGIEPWLKDFHQLLLNPPKKMSILTTIGVL
EEPLGNARLHGARLIAALLHTNTPSINQELCRLNTMDLLLDLFFKFTWNNFLHFQVELCI
AAILSHSAREGGMPAPESECRE--EMHRGNGN-----LEKTES-AEFPSENVMVTHLFQK
CCLVQRILDAWEANDRIXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXL
PEDCRGRWESFVEETLPETNRRNTVDLVSTHHLHSSSEDEDMESAFPNELSLQQ-AFSEYQIQQMTANFVDQFGFNDEEFADQDDNINAPFDRIAEINFNIDADD--DSPNASLFEACCNDRIQPFDDE------------EEDI

PF04499 // ENSGT00390000009899_2_Domain_4 (358, 745)

XXXXXXXXXXWLNEENIIERLVELIHSSQDEDXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXX-XXX-------XXXXXXXXXX----XXX--------XXXXXXXXXXXXXXXXXXXXXXXXXXVEGLTDSFSQGLERS-YTVNSSILHGIEPWLKDFHQLLLNPPKKMSILTTIGVLEEPLGNARLHGARLIAALLHTNTPSINQELCRLNTMDLLLDLFFKFTWNNFLHFQVELCIAAILSHSAREGGMPAPESECRE--EMHRGNGN-----LEKTES-AEFPSENVMVTHLFQKCCLVQRILDAWEANDRIXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXLPEDCRGRWESFVEETLPETNRRNTVDLVSTHHLHSSSEDEDMESAFPNELSLQQ-AFSEY
QIQQMTANFVDQFGFNDEEFADQDDNINAPFDRIAEINFNIDADD--DSPNASLFEACCN
DRIQPFDDE------------EEDIWEDKEINYATQAKSRTRFGASHTSEYSAKSNLENG
ARNGGEDSEEEEXXXXX-XXXXXXXXXX----------XX-----XXX-XXXXX-XXXXX
XXXX-------XXXXXX--XXXXXX-----XX--XXXXXXX-XX-----XXX--------
---XXXXXXXXXXXXXXXXXXXXXSPLAVSQSAPCVWNVCVARKAPLVASDSSSSGGSDS
EEEED---EKKSDIITETVGAGSGQEGLRLAVDTK-KEKAALTAV---------------
----ASAAIPMADIMPMPVSVTMPMPVA----------ATT------------AV-----
---LTAATTTVLTATLSAAASTVATTAALETVMKDRKEEAPPSPEATLNGPA

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MFWK
FDLNTTSHVDKLLDKEHVTLQELMDEDDILQECKAQNQKLL-DFLCRQQCMEE---LVSL
ITQDPPLDMEEKVRFKYPNTACELLTCDVPQISDR-LGGDESLLSLLYDFLDHEPPLNPL
LASF--FSKTI

PF04499 // ENSGT00390000009899_2_Domain_0 (312, 488)

GNLIARKTEQVIIFLKKKDKFISLVLKHIGTSALMDLLLRLVSCVEPAG
LRQEVLHWLNEEKVIQRLVELIHPSQDED-------------------------------
------------------------------------------------------------
------T

ENSGT00390000009899_2_Linker_0_5 (488, 498)

EGLVDSFSQG

PF04499 // ENSGT00390000009899_2_Domain_5 (498, 565)

LERS-YAVSSSVLHGIEPRLKDFHQLLLNPPKKKAILTTIGVL
EEPLGNARLHGARLMAALLHTNTP

ENSGT00390000009899_2_Linker_5_6 (565, 566)

S

PF04499 // ENSGT00390000009899_2_Domain_6 (566, 744)

INQELCRLNTMDLLLDLFFKYTWNNFLHFQVELCI
AAILSHAAREERTEASGSDSRV--EPPHENG---NRSLETPQP-AASLPDNTMVTHLFQK
CCLVQRILEAWEANDHTQAAGGMRRGNMGHLTRIANAVVQNLERGPVQTHISE--VIRGL
PADCRGRWESFVEETLTETNRRNTVDLVSTHHLHSSSEDEDIEGAFPNELSLQQ-AFSDY
QIQQMTANFVDQFGFNDEEFADQDDNINAPFDRIAEINFNIDADE--DSPSAALFEACCS
DRIQPFDD-----------DEDEDIWEDSDTRCAARVTARARFGAPHASESCSKNGPERG
GQDGNGSLEAHRD-----------APGAGAPPAPRKKEAP-TVEGDSE-GAMWTAVFDEP
ANST--PTAPGVVRDVGSSVWAAGT----SAPEEKGWAKFTDFQPFCCSESG---PRCSS
PVDTERSHAEGSRSQGPEKAS-QASCFAVSPASPCAWNVCVTRKAPLLASDSSSSGGSGS
KDGNQ-----RAASAMDAVSRGPGREVPPLPTVAR-TEEA----------------VGRV
GCA-DSRPLSPAC--PTPKEVTAAPAV--AVPPEATVAITTALSKAGPAIPTPAVSSAVA
VAAPLGPIMAVTAAPA--------MVATLGTVTKDGKTDAP-PEGAALNGPV

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MFWK
FDLNTTSHVDKLLDKEHVTLQELMDEDDLLQECKAQNRKLL-DFLCRQQCMEE---LVGL
ITQDPPLDMEEKVRFKNSSTTCPPHSCSATVFSDFPLLSFADFLWLMSDFLPHTLSLTIL
LCHFQIFSCVVREKER

PF04499 // ENSGT00390000009899_2_Domain_0 (317, 565)

DKTRQVIAFLKKKDKFISLVLKHIGTSALMDLLLRLVSCVEPAG
LRQEVLNWLNEEKIIQRLVELIHPSQDEDRQSNASQTLCDIIRLGRDQGSQLQEAT-EPD
PLLT-ALESQDCVEQLLKNMFDGDHTESCLVSGTQVLLTLLETRRAGT------------
-------ECAVDSFSQGLERS-FTVSSSVLHGLEPRLKDFHQLLLRPPKKKAILTTIGVL
EEPLGNARLHGARLMAALLHTNTP

ENSGT00390000009899_2_Linker_0_6 (565, 566)

S

PF04499 // ENSGT00390000009899_2_Domain_6 (566, 744)

INQELCRLNTMDLLLDLFFKYTWNNFLHFQVELCV
AAILSHAAAG----AGGPESKE--EPPRRDG-NAVRDPETPQP-ATSLPENTMVTHLFQK
CCLVQRILEAWEANDHTQAAGGMRRGNMGHLTRIANAVVQNLERGPVQTHISE--VIRGL
PADCRGRWESFVEETLVETNRRNTMDL----------------------------AFSEY
QIQQMTANFVDQFGFNDEEFADQDDNISAPFDRIAEINFSIDAEE--DSPSAALFEACCG
DRIQPFDD-----------DEEEDIWEDQETRGATRVMARARFGAPLAADSCSKKDLEHR
GRERKVDWEADGDAPAA-G--------TASAPAPAQNKGL-PLQGDSEAGTAWMAVFDEP
A-------APGVARDVGSSVWAAGAA----APEEKGWAKFADFQPFCCSESG---PRCSS
PVDTNHSCAEGAKSQGQEQAF--------SPASPCAWNVCIPRKGPLMASDSSSSGSSGE
DKQQ------KAIGVVEAASTGPGWETSLLPRTEA-A------------------AVGRT
QCV-DSRPPDPTC--PAPVEITRAPAVA--A---------------------PTVSSAMA
--------VVVTTAAPA-------VAADLGTVTKDRETDTP-PEGAALNGPV

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MFWK
FDLNTTSHVDKLLDKEHVTLQELMDEDDILQECKAQNQKLL-DFLCRQQCMEE---LVSL
ITQDPPLDMEEKVRFKYPNTACELLTCDVPQISDR-LGGDESLLSLLYDFLDHEPPLNPL
LASF--FSKTI

PF04499 // ENSGT00390000009899_2_Domain_0 (312, 569)

GNLIARKTEQVITFLKKKDKFISLVLKHIGTSALMDLLLRLVSCVEPAG
LRQEVLHWLNEEKVIQRLVELIHPSEDEDRQSNAAQTLCDIVRLGRDQGSQLQEAL-EPD
PLLT-ALESQDCVEQLLKNMFDGDRTESCLVSGTQVLLTLLETRRVG-------------
------TEGLVDSFSQGLERS-YAVSSSVLHGIEPRLKDFHQLLLNPPKKKAILTTIGVL
EEPLGNARLHGARLMAALLHTNTPSINQ

ENSGT00390000009899_2_Linker_0_6 (569, 569)

PF04499 // ENSGT00390000009899_2_Domain_6 (569, 744)

ELCRLNTMDLLLDLFFKYTWNNFLHFQVELCI
AAILSHAAREERTEASGSDSRV--EPPHENE---NRSLETPQL-ATSPPDNTMVTHLFQK
CCLVQRILEAWEANDHTQAAGGMRRGNMGHLTRIANAVVQNLERGPVQTHISE--VIRGL
PADCRGRWESFVEETLTETNRRNTVDL---------------------------------
-IQQMTANFVDQFGFNDEEFADQDDNINAPFDRIAEINFNIDADE--DSPSAALFEACCS
DRIQPFDD-----------DEDEDIWEDSDTRCAARVTARARFGVPHASESCSKNGLECR
SQDRKAS-SVDGD-----------VPGADAPPAPGKNEAP-TVEGDSE-GATWTAVFDEP
ANLT--PMAPGVVRDVGSSVWAAGT----SAPEEKGWAKFTDFQPFCCAESG---PRCSS
PVDTECSHAEGSHSQGPEKA--------SSPASPCAWNVCATRKAPLLASDSSSSGGSDS
GDEDQ-----KAATAVEAVSRGPGWEAPALPAVTR-TEEA----------------VSRA
ECA-DSKLLDPAC--PVPKEVTADPAV--AAHPEATVATTTALSKAGPPIATPAVSSAVA
VAAPLGPIMAVTTAPA--------MVATLGTVTKDRKTDAP-PEGAALNGPM

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MFWK
FDLNTTSHVDKLLDKEDVTLRELMDEDDILQECKAQNRKLL-DFLCRPQCMEE---LVSL
ITQDPPLDMDEKVRFKYPNTACELLTCDVPQINDR-LGGDEALLNLLYDFLDHEPPLNPL
LASF--FSKT

PF04499 // ENSGT00390000009899_2_Domain_0 (311, 745)

IGSLIARKTEQVIVFLKRKDTFISLVLKHIGTSALMDLLLRLVSCVEPAG
LRQEVLRWLNEERIIQRLVELIHPREDEDRQSNASQTLCDIVRLGREQGSQLPEAL-EPD
PLLA-VLESQDCVEQLLRNMFDGDQTESCLVSGTQVLLTLLEARRAGT------------
------EG-LVDAFSQGLERL-CPVSGSVLHGIEPRLKDFHQLLLHPPKKAAILTTIGVL
EEPLGNARLHGARLMAALLHTNTPSINQELCRLNTMGLLLDLFFKYTWNNFLHLQVELCV
AAILSQAPREDRAEASGPESG---------------DSESPRP-AASHPESTMVTHLFQK
CCLVQRILEAWEANDHTQAAGGMRRGNMGHLTRIANAVVRNLERGAMQTPVGE--VIQGL
PADCRGRWESFVEETLTETNRRNAVDLVST-HLHPSSEDEDMEGVFPNELSLQQ-AFSEYQVQQMTATFVDQFGFNDEEFADQDDSVNAPFDRIAEIN

PF04499 // ENSGT00390000009899_2_Domain_4 (311, 745)

IGSLIARKTEQVIVFLKRKDTFISLVLKHIGTSALMDLLLRLVSCVEPAGLRQEVLRWLNEERIIQRLVELIHPREDEDRQSNASQTLCDIVRLGREQGSQLPEAL-EPDPLLA-VLESQDCVEQLLRNMFDGDQTESCLVSGTQVLLTLLEARRAGT------------------EG-LVDAFSQGLERL-CPVSGSVLHGIEPRLKDFHQLLLHPPKKAAILTTIGVLEEPLGNARLHGARLMAALLHTNTPSINQELCRLNTMGLLLDLFFKYTWNNFLHLQVELCVAAILSQAPREDRAEASGPESG---------------DSESPRP-AASHPESTMVTHLFQKCCLVQRILEAWEANDHTQAAGGMRRGNMGHLTRIANAVVRNLERGAMQTPVGE--VIQGLPADCRGRWESFVEETLTETNRRNAVDLVST-HLHPSSEDEDMEGVFPNELSLQQ-AFSEY
QVQQMTATFVDQFGFNDEEFADQDDSVNAPFDRIAEINFHIDADE--DSPSAALFEACCG
DHIQPFDD-----------DEDDDIWEDKEAHCAARGLGRARFGGPPATESCPENGLARG
DRDGEEANGD--------------VAPAGAPQVAAQKGSP-HVEGGSE-GATWT-VFDEP
ASPT--AATPGVAMDVGSSVWAARAP-STTALEEKGWAKFPDFQPFCCSELG---PRCSS
PVDVGPGDAQGGLSQGPERTLSPGPCLAVGSASPCAWNVCVSRDAPLVASGSD-------
-EDE------QVAVTSEAVSMGPGQEAPPLPTPVP-RRGQ---------------AVPRP
SCPVASTLPGPTS---APAEATSTLAG--AVPPEA---ASTALSKASP---APAPAGVLA
VAVPPGPMVAVTTTA--TASPAVSTVAILGTVTKDRKTAAP-PAGAASNGPV

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MFWK
FDLNTTSHIDKLLDKEHVTLQELMDEDDVLQECKAQNRKLL-DFLCRPQCMEE---LVNL
ITQDPPSDMEEKV----------------------------------------QPPLNPL
LASF--FSKTI

PF04499 // ENSGT00390000009899_2_Domain_0 (312, 569)

GNLIARKTEQVIVFLKKKDKFTSLVLKHMGTSALMDLLLRLVSCVEPMG
LRQEVLHLLVAEISV---------SLSLQRQSNASQALCDIVRLSRDQSSQLQETL-KPD
PLLV-ALESQDCVEQLLKNMFDGDQTESCLVSGMQVLLALLEPRRAGT------------
-------EGLVDSFSQGLERS-HAVSISVLNGIEPRLKDFHQLLLNPPKKKAILTTIGVL
EEPLGNARLHGARLMAALLYTNTPSINQ

ENSGT00390000009899_2_Linker_0_6 (569, 569)

PF04499 // ENSGT00390000009899_2_Domain_6 (569, 744)

ELCRLNTMDLLLDLFFKYTWNNFLHFQVELCI
AAILSHAAGEERAEAGGSESKV--EPPQGSGN-GNRSLETPQP-VASLPENTMVTHLFQK
CCLVQRILEAWEANDHTQAAGGMRRGNMGHLTRIANSVVQNLERGPVQTHISE--VIQGL
PADCRGRWESFVEETLTETNRRNTVDL----------------------------AFSEY
QIQQMTAHFVDQFGFND-EFADQDDSVNAPFDRIAEINFNIDADE--DSPSTALFEACCS
DRIQPFDD-----------EEEEDIWEDEETCSTSRVMARARCGAHPLD-----------
------------------------------------------AASPAA-HAAWTAVFDEP
VIPA--APVPGAASDVGSSVWAAGA----LASEEKGWAKFTDFQPFCCFCAECGAVMCSG
PH------RRGFSSQPPYFTV--------GPASPCAWNVCVARKAPLVASDSSSSGGSDS
EDEEK------AAGTAETVSSGPSREAPSPPRKEA--------------------AAGRA
ECVS-CTPPDSAG--PVPSKVTSALAM--AVSLEAT-M------------ATPVVSTAMA
EALPAGPIMEVTTIPA--------PVATLGTVTKDRETDAR-PEGAALNGPV

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MFWK
FDLNTTSHVDKLLDKEHVTLQELMDEDDILQECKAQNQKLL-DFLCRQQCMEE---LVNL
ITQDPPQDMEEKVRFKYPNTACELLTCDVPQISDR-LGEDESLLNLLYDFLDQEPPLNPL
LASF--FSKTI

PF04499 // ENSGT00390000009899_2_Domain_0 (312, 569)

GNLIARKTEQVIMFLKKKEKFISQLLKHIGTSALMDLLLRLVSCVEPVG
LRQEVLHWLNEEKIIQRLVELIHPHQDEDRQSNASQALCDIIRLGRDQGSQLQETV-EPD
PLLI-TLESQDCVEQLLKNMFDGDQTESCLVSGMQVLLALLEPRRVGT------------
------EG-LVDSFSQGLERS-HSVSSSILRGIEPWLKNFHQLLLNPPKKKAILTTIGVL
EEPLGNARLHGARLMAALLHTNTPGINQ

ENSGT00390000009899_2_Linker_0_6 (569, 569)

PF04499 // ENSGT00390000009899_2_Domain_6 (569, 744)

ELCRLNTMDLLLDLFFKYTWNNFLHLQVELCI
AAILSHAAREEQSEASGSDGKV--EPLQGSGD-GNGKLETTPS-ITSPPENTMVTHLFQK
CCLVQRILEAWEANDHTQAAGGMRRGNMGHLTRIANAVVQNLEQGPVQAHISE--VIRGL
PADCRGRWESFVEETLMETNRRNTVDL----------------------------AFSEY
QIQQMTANFVDQFGFNDEEFADQDDNINTPFDRIAEINFNIEADE--DSPSAALFEACCS
DRIQPFDD-----------EEEEDIWEDDETRCAARVMARARFGAPHVSDNYSKNALEHG
GQDRKTGSAVARN-----------VPGLAAPSSPTQKEGP-RSESDSA-GTTWTAVFDEP
VNPL--SATPGAARDVGSSAWAAGP----SVVEEKGWAKFTDFQPFCCSETG---PRCSS
PVDMDHSNAEGGHSPGPEKTF--------GPTSPCAWNVCVTRKAPLVASDSSSSGGSDS
EDDEK------AAGAVEAVCTGHTGKVSPPP---R-TAEA---------------AVGRA
ECP-DSTVLAPAC--PAPSEVTISPAV--ATI---------APSKAGSPTATIVVSSSVA
AAVPPGPIVAVTTAAPA-------IVATLGTMTKDRKADAL-PEGAALNGPV

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MFWK
FDLSTTSHVDKLLDKEDVTLRELMDEDDILQECKAQNRKLL-DFLCRQQSMEE---LVSL
VTQDPALGVEEKVRFKYPNTACELLTCDVPQISDR-LGGDETLLNLLYDFLNREPPLNPL
LASF--FSKT

PF04499 // ENSGT00390000009899_2_Domain_0 (311, 723)

IGSLIARRTAQVIVFLRKKDKFISLLLKHIGTSALMDLLLRLVSCVEPAG
LRQEVLHWLNEEKLIQRLVELIHPSQDEDRQSNASQTLCDIVRLGREQGSPLQEAP-EPD
PLLM-ALESQDCVERLLRNMFDGAQTELCLVSGTQVLLTLLEPRRAGX------------
------XXXXXXXXXXXXXXX-XXX-XXXXXXXXXXXXXXXXXXXXXXXKAAILTTIGVL
EEPLGNARLHGARLVAALLHTNTPSINQELCRLNTMGLLLDLFVKYAWNNFLHFQVELCI
AAILSHSAREDRAVASGPEGAV--EPLPSSGD-----PETPRP-AASRPESTMVTHLFQK
CCLVQRILEAWEANDHTQAAGGMRRGNMGHLTRIANAVVQSLEGGPVQTQVSE--VLRXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSSEDEDMEGVFPNELSLQQ-AFSEYQVQQMTATFVDQFGFSDEEFAEQDDSVNAPFDRIAEINFSVDADE--DSPGAALFEACCS

PF04499 // ENSGT00390000009899_2_Domain_4 (311, 723)

IGSLIARRTAQVIVFLRKKDKFISLLLKHIGTSALMDLLLRLVSCVEPAGLRQEVLHWLNEEKLIQRLVELIHPSQDEDRQSNASQTLCDIVRLGREQGSPLQEAP-EPDPLLM-ALESQDCVERLLRNMFDGAQTELCLVSGTQVLLTLLEPRRAGX------------------XXXXXXXXXXXXXXX-XXX-XXXXXXXXXXXXXXXXXXXXXXXKAAILTTIGVLEEPLGNARLHGARLVAALLHTNTPSINQELCRLNTMGLLLDLFVKYAWNNFLHFQVELCIAAILSHSAREDRAVASGPEGAV--EPLPSSGD-----PETPRP-AASRPESTMVTHLFQKCCLVQRILEAWEANDHTQAAGGMRRGNMGHLTRIANAVVQSLEGGPVQTQVSE--VLRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSSEDEDMEGVFPNELSLQQ-AFSEY
QVQQMTATFVDQFGFSDEEFAEQDDSVNAPFDRIAEINFSVDADE--DSPGAALFEACCS
DHIQPFDE-------------DDDLWEDEETHCVARV-TRARFGGPHASESCRKDGLEHR
GQGGEESSEADG-------------ARAGAPRAAVQEEGP-RVEGGSE-GAPWT-VSDEP
VNSTASGLAPAVAMDVGSSVWAASAP-SASAAEERGWAKFADFQPFCCSESG---PRCSS
PVDRGHGDAQGGLNRGPERTP-PAPCVAAGPATLGAWNACVARKAPLVASSSR-------
-EDKQ-----KVALASEAVRMGPGREAPPPPVLVP-R----------------------S
ECA-ASTPPDLAS--LAPVEVTSAPVG--AVLREAAVAATTVPGNTGPASATPAVSPVLA
VAV-------------TPAAPAVSTAATLGTVTKDRQTDGPPPAGAALNGLV

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MFWK
FDLNTTSHVDKLLDKEHVTLQELMDEDDILQECKAQNQKLL-DFLCRQQCMEE---LVSL
ITQDPPLDMEEKVRFKYPNTACELLTCDVPQISDR-LGGDESLLSLLYDFLDHEPPLNPL
LASF--FSKTI

PF04499 // ENSGT00390000009899_2_Domain_0 (312, 569)

GNLIARKTEQVITFLKKKDKFISLVLKHIGTSALMDLLLRLVSCVEPAG
LRQEVLHWLNEEKVIQRLVELIHPSQDEDRQSNASQTLCDIVRLGRDQGSQLQEAL-EPD
PLLT-ALESQDCVEQLLKNMFDGDRTESCLVSGTQVLLTLLETRRVG-------------
------TEGLVDSFSQGLERS-YTVSSSVLHGIEPRLKDFHQLLLNPPKKKAILTTIGVL
EEPLGNARLHGARLMAALLHTNTPSINQ

ENSGT00390000009899_2_Linker_0_6 (569, 569)

PF04499 // ENSGT00390000009899_2_Domain_6 (569, 744)

ELCRLNTMDLLLDLFFKYTWNNFLHFQVELCI
AAILSHAAREDRTEASGSESRA--EPLHENG---NRSLETPQP-PASLPDNTMVTHLFQK
CCLVQRILEAWEANDHTQAAGGMRRGNMGHLTRIANAVVQNLERGPVQTHISE--VIRGL
PADCRGRWESFVEETLTETNRRNTVDLVSTHHLHSSSEDEDIEGAFPNELSLQQ-AFSDY
QIQQMAASFVDQFGFNDEEFADQDDNINAPFDRIAEINFNIDADE--DSPSAALFEACCS
DRIQPFDD-----------DEDEDIWEDSDTRCATRVMARARFGAPHASDSSSKNGPERG
GQDGKASSEAHGD-----------APGAGAPPAPGKKEAP-TVEGDSE-GAMWTAVFDEP
ANST--PTAPGVVRDVGASVWAAGT----SAPEEKGWAKFTDFQPFCCSESG---PRCSS
PVDTERSRAEGSRSQGPEKA--------FSPASPCAWNVCVTRKAPLLASDSSSSGGSDS
-EDYQ-----KAASAVDAVSRSPGREAPPRPTGAR-TEEA----------------VGRA
VCA-NSRLLDPAC--PAPKEVTAAPAM--APPPEAAVAITTALSKAGPAIPSPAVSSAVA
VAVPLGPIMAVTTAPA--------MVATLGTVTKDGKRDAP-PEGAALNGPV

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MFWK
FDLNTTSHIDKLLDKEHVTLQELMDEDDILQECKAQNQKLL-DFLCRQQCMEE---LVNL
ITQDPPLDMEEKVRFKYPNTACELLTCDVPQISDR-LGEDESLLNLLYDFLDQEPPLNPL
LASF--FSKTI

PF04499 // ENSGT00390000009899_2_Domain_0 (312, 569)

GNLIARKTEQVIMFLKKKEKFISLMLKHVGTSALMDLLLRLVSCVEPVG
LRQEVLHWLNEEKIIQRLVELIHPHQDEDRQSNASQALCDIIRLGRDQGSQLQEAV-DPD
PLLL-TLESQDCVEQLLKNMFDGDQMESCLVSGMQVLLALLEPRRVGT------------
------EG-LVDSFSQGLERS-ESVNSSILHGIEPWLKNFHQLLLHPPKKKAILTTIGVL
EEPLGNARLHGARLMAALLHTNTPSINQ

ENSGT00390000009899_2_Linker_0_6 (569, 569)

PF04499 // ENSGT00390000009899_2_Domain_6 (569, 744)

ELCRLNTMDLLLDLFFKYTWNNFLHFQVELCI
AAILSHAAREEPAEASGSNGKV--EPLQGSGD-GTGKPETPQS-VTSLPENTMVTHLFQK
CCLVQRILEAWEANDHTQAAGGMRRGNMGHLTRIANAVVQNLEQGPVQTHISE--VIRGL
PADCRGRWESFVEETLMETNRRNTVDLVSTHHLHSSSEDEDIEGTFPNELSLQQ-AFSEY
QIQQMTANFVDQFGFNDEEFADQDDNINAPFDRIAEINFNIEADE--DSPTAALFEACCS
DRIQPFDD-----------EEEEDIWEDEETRCTARVMARARFGAPHVSENYSKNSLEHG
GQDRKAGLAAARN-----------VPGLATPSSPTQKEGP-RSDSDLE-GTTWTAVFDEP
VNPM--SAAPGASRDVGSSVWAAGP----SAPEEKGWAKFTDFQPFCCSESG---PRCSS
PVDMDHSHAEGGQSPGPEKAF--------GPTSPCAWNVCVTRKAPLVASDSSSSGGSDS
EEDEK------AAGAVEAVCTGHGGKASPLP---K-TEEA---------------VASRA
ECT-DSTVLAPAC--PSSPEVIISSAV--ATT---------APSKAGPPTATIVVSSSVA
TTVPPGPIMAVTTAAPA-------LVATLG--TKDRKTDAL-PEGAALNGPV

MPRERPWKREKDQKKKKKRKCITAKASLYRKLQKPRNTSAGGERDAAQAPPRAVPAPAPP
RPGPAPALACAPPDEAPPSARPRAPGPRCRHFGATRVLLAARAGPEAPAGRAVSVGAVSV
GASLGRAHVRAARPRPPGLRLRPRPGLHPG--------LRGAAATPGPRGSSAAVTMFWK
FDLNTTSHIDKLLDQEDVTLRELMDEDDILQECKAQNRRLL-DFLCRPQCMEE---LVNL
VTQDPALDVEEKVRFKYPNTACELLTCDVPQINDR-LGGDETLLNLLYDFLDREPPLNPL
LASF--FSKTI

PF04499 // ENSGT00390000009899_2_Domain_0 (312, 569)

GNLIARKTEQVIVFLRKKDKFISLVLKHIGTSALMDLLLRLVSCVEPAG
LRHEVLQWLNEEKVIQRLVELIHPSQDEDSQSNASQTLCDIVRLGREQGGQRQEAP-EPD
PLLT-VLESQDCVEQLLRNMFDGAQTEGCLVSGTQVLLTLLETRRPGT------------
------EG-LVDSCSQGLDRL-CAVSSGVLLGIEPRLKDFHQLLLSPPKKKAILTTIGVL
EEPLGNARLHGARLVAALLHTNTPSINQ

ENSGT00390000009899_2_Linker_0_6 (569, 569)

PF04499 // ENSGT00390000009899_2_Domain_6 (569, 744)

ELCRLNTMGLLLDLFFKYTWNNFLHFQVELCV
AAILSHAAREDRAVASGPEVGA--EPAASSRD-----PETPQP-AASHPEDTMVTHLFHK
CCLVQRILEAWEANDHTQAAGGMRRGNMGHLTRIANAVVQNLEGGPMQTHVSE--VIRGL
PADCRGRWASFVEETLTEANRRNAVDLVSTRLLHPSGEDEDVEAAFPNELSLQQ-AFSEY
QVQQMTATFVDQFGFSDEEFAEQDDSVNAPFDRIAEINFSVDAEE--DSPGAALFEACCS
DHIQPFDE-------------EDDLWQAEATQRAARV-TRARFGGPRAPESQDG------
----AERAEAHG-----------FAARAGALQASTQKEGP-REEGGSQ-GAAWT-VFDEP
GSSLASGPAPGAVVDVGSSVWAASPP-SASAPEEKGWAKFADFQPFCCSESG---PRCSS
PVDTGHGDAQGSGTQGPERSL--------GPATLCARNVCVTRKAPLGVSSSC-------
-EDQQ-----KVAGALEAVSMGPAREAPLTPEPGP-RA----------------------
ECA-TNMPPGLAS--LASAEVTSAPGV--AVLPEAAVAATTVPSSTGPSPATLTISPVPA
-------AVAVTTA--APVSPAISSAAALGLVTKNRKTDVAPPAGAALNGPV

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MFWK
FDLNTTSHIDKLLDKEHVTLQELMDEDDILQECKAQNRKLL-DFLCRPQCMEE---LVNL
ITQDPPLDMEEKVRFKYPNTACELLTCDVPQISDR-LGGDESLLNLLYDFLDREPPLNPL
LASF--FSKTI

PF04499 // ENSGT00390000009899_2_Domain_0 (312, 569)

GNLIARKTEQVIVFLKKKDKFISLVLKHMGTSALMDLLLRLVSCVEPVG
LRQEVLHWLNEEKIIQRLVELIHPHQDEDRQSNASQALCDIVRLSRDQSSQLQETL-EPD
PLLT-ALESQDCVEQLLKNMFDGDQTESCLVSGMQVLLALLEPRRAGT------------
-------EGLVDSFSQGLERS-HAVSSSVLNGIEPRLKDFHQLLLNPPKKKAILTTIGVL
EEPLGNARLHGARLMAALLHTNTPSINQ

ENSGT00390000009899_2_Linker_0_6 (569, 569)

PF04499 // ENSGT00390000009899_2_Domain_6 (569, 744)

ELCRLNTMDLLLDLFFKYTWNNFLHFQVELCI
AAILSHAAREERAEAGGSESRV--EPPQGSGN-GNRSLETPQP-VASLPENTMVTHLFQK
CCLVQRILEAWEANDHTQAAGGMRRGNMGHLTRIANSVVQNLEQGPVQTHISE--VIQGL
PADCRGRWESFVEETLTETNRRNTVDL----------------------------AFSEY
QIQQMTAHFVDQFGFND-EFADQDDSINAPFDRIAEINFNIDADE--DSPSTALFEACCS
DRIQPFDD-----------EEEEDIWEDEETRSTARVMARARFGAPHSSESCSKNGLERE
GQDRKAGSEADRNK-----------PGAATPLALAQNEGF-S-EGNSE-DAAWTAVFDEP
VNPT--APVPGAARDVGSSVWAAGA----SAPEEKGWAKFTDFQPFCCSESG---PRCSS
PVDTDHSHAENGQSPSPEKAF--------GPASPCAWNVCVTRKAPPVASDSSSSGGSDS
EDEEK------AAGIAETVSSGPSLEAPSPPRKED--------------------AAGRA
ECVG-STPPDSAC--PVPSKVTCPAM------------ATPALDKASLPPAHPAVCTAVA
VAVPAGPIVEVTTAPA--------TVATLGTVTKDRETDAP-PGAAALNGPV

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MFWK
FDLNTTSHVDKLLDREDVTLRELMDEDDILQECKAQNQKLL-GFLCRQQCMEE---LVSL
ITQDPPLDMEEKVRFKYPNTACELLTCDVPQINDR-LGGDETLLNLLYDFLDHEPPLNPL
LASF--FSKT

PF04499 // ENSGT00390000009899_2_Domain_0 (311, 745)

IGNLIARKTEQVIQFLKKKDGFLSLVLKHIGTSALMDLLLRLVSCVEPAG
LRQDVLHWLNEEKIIQRLVELIHPSQDEDRQSNASQTLCDIIRLGREQASQLQEAP-EPD
RLLT-VLESQDCVEQLLKNMFDGDQTESCLVSGTQVLLTLLETRRAGT------------
------EG-LVDSFSQGLEGL-CTVSSSVLHGIEPRLKDFHQLLLSPPKKKAILTTIGVL
EEPLGNARLHGARLMAALLHTNTASINQELCRLNTMGLLLDLFFKYTWNNFLHFQVELCI
AAILSHAARGDRAEASGPDSRV--ELLPGNGD-----PETPQP-AASLPENTMVTHLFQK
CCLVQRILEAWEANDHAQAAGGMRRGNMGHLTRIANAVAQNLERGPMQTHICEQCSLAGL
PADCRGRWENFVEETLAETNRRNAVDLVSTHHLHPSSEDEDMEGVFPNELSLQQ-AFSEYQVQQMTATFVDQFGFNDEEFADQDDSVNAPFDRIAEIS

PF04499 // ENSGT00390000009899_2_Domain_4 (311, 745)

IGNLIARKTEQVIQFLKKKDGFLSLVLKHIGTSALMDLLLRLVSCVEPAGLRQDVLHWLNEEKIIQRLVELIHPSQDEDRQSNASQTLCDIIRLGREQASQLQEAP-EPDRLLT-VLESQDCVEQLLKNMFDGDQTESCLVSGTQVLLTLLETRRAGT------------------EG-LVDSFSQGLEGL-CTVSSSVLHGIEPRLKDFHQLLLSPPKKKAILTTIGVLEEPLGNARLHGARLMAALLHTNTASINQELCRLNTMGLLLDLFFKYTWNNFLHFQVELCIAAILSHAARGDRAEASGPDSRV--ELLPGNGD-----PETPQP-AASLPENTMVTHLFQKCCLVQRILEAWEANDHAQAAGGMRRGNMGHLTRIANAVAQNLERGPMQTHICEQCSLAGLPADCRGRWENFVEETLAETNRRNAVDLVSTHHLHPSSEDEDMEGVFPNELSLQQ-AFSEY
QVQQMTATFVDQFGFNDEEFADQDDSVNAPFDRIAEISFSVDADE--DSPSAALFEACCG
DHIQPFDD-----------DEEDDIWEDKEMHCTARVTARARFGGPHTSESCSKNGLERG
SQDRKEVLEADKG-----------AARAGAPLASTQKEGP-RLEGGSGAGTSWT-VFDEP
VNSP--VPAPGVAVDVGSNVWAASTP-SPSALEEKGWAKFTDFQPFCCSESG---PRCSS
PVDMGHGDSQDGPNQGPERAR-QQLRLIVGPASPCAWSTCVTRKAPLV-SDSS-------
-EDEQ-----KMAGALEAVSLGPSQEAPPLPASVP-RSEGSV--------------DRA-
-DCTASTPSDPTS--PAPAEANFAPAV--AVPPEAAVAATPALSKASPAPATVA------
--GPTGPIVAITTAAPA-----VCTAAILGTVTKDRKMDSPPPAA--VNGPV

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MFWK
FDLNTTSHVDKLLDKEHVTLRELMDEDDILQECKAQNQKLL-DFLCRQQSMEE---LVNL
ITQDPPLDVEEKVRFKYPNTACELLTCDVPQISDR-LGGDESLLSLLYDFLDHEPPLNPL
LASF--FSKTI

PF04499 // ENSGT00390000009899_2_Domain_0 (312, 569)

GNLIARKTEQVIVFLKKKDKFISLVLKHIGTSALMDLLLRLVSCVEPAG
LRQEVLHWLNEEKIIQRLVELIHPGQDEDRQSNASQTLCDIVRLGRDQGSQLQEAL-EPD
PLLT-ALESQDCVEQLLKNMFDGDWTESCLVSGTQVLLTLLETRRAGA------------
------EG-LVDSFSQGLERS-HAVSGSILHGITPRLKDFHQLLLSPPKKEAILTTIGVL
EEPLGNARLHGARLMAALLHTNTPSINQ

ENSGT00390000009899_2_Linker_0_6 (569, 569)

PF04499 // ENSGT00390000009899_2_Domain_6 (569, 744)

ELCRLNTMDLLLDLFFKYTWNNFLHFQVELCI
AAILSYAAREEGAEANGAECRM--EPACGNGNSS---WESPQPAAASLPENTMVTHLFQK
CCLVQRILEAWETNDHIQAAGGMRRGNMGHLTRIANAVVQNLERGPMQAHISE--VIRGL
PADCRGRWESFVAETLTETNRRNTVDLVSIHHLHSSSEDEDIEGAFPNELSLQQ-AFSEY
QIQQMTANFVDQFGFNDEEFADQDDNINAPFDRIAEINFSVDADD--DSPSAALFEACCS
DRIQPFDD-----------E-EEDIWEDKETRCATRVMARARFGVPHAPESCSEDGL---
--DGKASPEADRN-----------TPGTDPPPAPGRKEGP-SVEADSE-GTAWTAVFDEP
VNST--PTAPGVARDVGSSVWAAGT----SAPEEKGWAKFTDFQPFCCSESG---PRCSS
PVDTERGRAGGSPSPSLEKAYSSCLAVDPGPPPPCAWNVCVTRKAPLVASDSE-------
-EEEQ-----KAGGATGAGSRGPGQEASPLPEAAR-SEEA---------------GVGGA
ACA-DRTLPDPAC--HAPVDVTPSPAV--AAPLKATVATTTALSRPGPPVYTPAVSSTVA
V---------AVTIAPA-------LVAASGTVAKDGKTDAP-PEGAALNGPV

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MFWK
FDLNTTSHVDKLLDKEHVTLQELMDEDDILQECKAQNQKLL-DFLCRQQCMEE---LVNL
ITQDPPLDMEEK-------------------ISDR-LGEDESLLNLLYDFLDQEPPLNPL
LASF--FSKTI

PF04499 // ENSGT00390000009899_2_Domain_1 (312, 368)

GNLIARKTEQVIMFLKKKDKFINLMLKHIGTSALMDLLLRLVSCVEPVG
LRQEVLHVSARDFV----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MFWK
FDLNTTSHVDKLLDKEHVTLQELMDEDDILQECKAQNQKLL-DFLCRQQCMEE---LVSL
ITQDPPLDMEEKVRFKYPNTACELLTCDVPQITDR-LGGDESLLSLLYDFLDHEPPLNPL
LASF--FSKTI

PF04499 // ENSGT00390000009899_2_Domain_2 (312, 366)

GNLIARKTEQVITFLKKKDKFISLVLRHIGTSALMDLLLRLVSCVEPAG
LRQEV

ENSGT00390000009899_2_Linker_2_0 (366, 390)

LH----------------------

PF04499 // ENSGT00390000009899_2_Domain_0 (390, 569)

RQSNASQTLCDIVRLGRDQGSQLQEAL-EPD
PLLT-ALESQDCVEQLLKNMFDGDRTESCLVSGTQVLLTLLETRRVG-------------
------TEGLVDSFSQGLERS-YTVSSSVLHGIEPRLKDFHQLLLNPPKKKAILTTIGVL
EEPLGNARLHGARLMAALLHTNTPSINQ

ENSGT00390000009899_2_Linker_0_6 (569, 569)

PF04499 // ENSGT00390000009899_2_Domain_6 (569, 744)

ELCRLNTMDLLLDLFFKYTWNNFLHFQVELCI
AAILSHSAREDRTEVSGSESRA--EPLHENG---NRSLETPQP-PASLPDNTMVTHLFQK
CCLVQRILEAWEANDHTQAAGGMRRGNMGHLTRIANAVVQNLERGPVQTHISE--VIRGL
PADCRGRWESFVEETLTETNRRNTVDLVSTHHLHSSSEDEDIEGAFPNELSLQQ-AFSDY
QIQQMAASFVDQFGFNDEEFADQDDNINAPFDRIAEINFNIDADE--DSPSAALFEACCS
DRIQPFDD-----------DEDEDIWEDSDTRCATRVMARARFGAPHASESCSKNGPERG
GQDGKASSEAHGD-----------APGAGAPPAPGKKEAS-AVEGDSE-GAMWTAVFEEP
ANST--PTAPGVVRDVGSSVWAAGT----SAPEEKGWAKFTDFQPFCCSESG---PRCSS
PVDTERSRAEGSRSQGPEKAS-QASSFAVSPASPCAWNVCVTRKAPLLASDSSSSGGSDS
EDNYQ-----KAASAVDAVSRGPGREAPPLPTVAR-TEEA----------------VGRA
ECP-DSRLLDPAC--PTPKEVTAAPAM-------AAVAITTALSKAGPAIPTPAVSSAVA
VAVPLGPIMAVTTAPA--------MVATLGTVTKDRKTDAP-PEGAALNGPV

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------V

PF04499 // ENSGT00390000009899_2_Domain_4 (323, 963)

IVFLKKKDGFINSVLRHLGTSAMMDLLLRLVSCVEPVG
LRHEVLHWLNEEKVIERLVGLIHPGQEEDRQFNASETPCDLLRLARDTMVQLQENGRSPH
PLLX-XXXXQGCVEQLLRNMFDGDQSESCLVHGTQVLLSLLEPRRPGT------------
------EGGLLDPVSRGLEQP-HSVSSSVLRAIELRLPDFHCLLLSPPKKSAILTTVGLL
EEPLGNARLHGARLVAALLHTGAPSVHQELCRLNTMDLLLXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXX--XXXXXXXX----XXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXAPFDRVAEISFSTEADDTSDSPPVALFEACCS
DHIQPFDDD------------EEDIWEDGELSRSARVTAR--------------------
-------------------------------------------------APGWE-TFVEP
EH

PF04499 // ENSGT00390000009899_2_Domain_6 (323, 963)

IVFLKKKDGFINSVLRHLGTSAMMDLLLRLVSCVEPVGLRHEVLHWLNEEKVIERLVGLIHPGQEEDRQFNASETPCDLLRLARDTMVQLQENGRSPHPLLX-XXXXQGCVEQLLRNMFDGDQSESCLVHGTQVLLSLLEPRRPGT------------------EGGLLDPVSRGLEQP-HSVSSSVLRAIELRLPDFHCLLLSPPKKSAILTTVGLLEEPLGNARLHGARLVAALLHTGAPSVHQELCRLNTMDLLLXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXX----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXAPFDRVAEISFSTEADDTSDSPPVALFEACCSDHIQPFDDD------------EEDIWEDGELSRSARVTAR---------------------------------------------------------------------APGWE-TFVEPEHAA--PQAPGAALDAGPIVWAGSSP---AAPATEGWATFTDFQLFCXXXXX---XXXXX
XVDTDGSDIQGGPDQGPEQTL----CIAAGPAPPSAWSTCVPKKVPPAGSSGRSSERA--
--------------VSKTAGLGFSQETPLQAAEASPRGGG------------------RT
AT-----LPE--------------------MTPPTTEPTPTALSKAGHSAPPLVTSTAVA
VVAPPGPIVVAT--------------------IRDRK--TEPPPGATSNGPV

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MFWK
FDLNTTSHIDKLLDKEHVTLQELMDEDDILQECKAQNRKLL-DFLCRPQCMEE---LVNL
ITQDPPWDMEEKVRFKYPNTACELLTCDVPQISDR-LGGDESLLNRLYDFLDREPPLNPL
LASF--FSKTI

PF04499 // ENSGT00390000009899_2_Domain_0 (312, 569)

GNLIARKTEQVIVFLRKKDRFISQVLKHMGTSALMDLLLRLVSCVEPLG
LRQEVLHWLNEEKVIQKLVELIHPRQDEDRQSNASQALCDIVRLSRDQSSQLQENL-EPD
PLLT-ALESQDCVEQLLKNMFDGDQTESCLVSGMQVLLALLEPRRAGT------------
-------EGLVDSFSQGLERS-HTVSSSVLNGIEPRLKDFHQLLLNPPKKKAILTTIGVL
EEPLGNARLHGARLMAALLSTSTPSINQ

ENSGT00390000009899_2_Linker_0_6 (569, 569)

PF04499 // ENSGT00390000009899_2_Domain_6 (569, 744)

ELCRLNTMDLLLDLFFKYTWNNFLHFQVELCI
AAILSHAAREERAEVRGSESRA--ELPQESGN-ENKNLETPQP-VVCLPENTMVTHLFQK
CCLVQRILEAWEANDHTQAAGGMRRGNMGHLTRIANSVVQNLEQGPVQTHISK--VIQGL
PADCRGRWESFVEETLTETNRRNTVDL----------------------------AFSEY
QIQQMTAHFVDQFGFND-EFADQDDSINAPFDRIAEINFNIDTDE--DSPSTALFEACCS
DRIQPFDD-----------EEEEDIWEDEETRSTARVMARARFGAPHNSESCSKNGVEHD
GRDRKAGSEADGNK-----------PGAVIPLALAQNEGF-SSEGNST-NAAWTAVFDEP
VSPT--APAPGAARDVGSSVWAAGA----SAPEEKGWAKFTDFQPFCCSESG---PRCSS
PVDTDRSHAESGPSPSPEKAF--------GPAPPCAWNVCVTRKAPLVASDSSSSGGSDS
EDEEK------LAATAEPVSSGLGREAPSPPRKQD--------------------TVGRA
ECAG-STPPDSAC--PVPSKVPCPGM------------ATPAVDKASPPAATPAVSTAVA
VAVPAGPITKVTKVPA--------TVTTLGTVTKDRETDGP-PGGAALNGPV

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MHWA
MDCFVSVFI-----------------------------TWV-CFLRNRLCKQLPKSWRSL
I-S-P--PVLGLCPFRYPNTACELLTCDVPQISDR-LGGDESLLSLLYDFLDHEPPLNPL
LASF--FSKTI

PF04499 // ENSGT00390000009899_2_Domain_0 (312, 569)

GNLIARKTEQVITFLKKKDKFISLVLKHIGTSALMDLLLRLVSCVEPAG
LRQEVLHWLNEEKVIQRLVELIHPSQDEDRQSNASQTLCDIVRLGRDQGSQLQEAL-EPD
PLLT-ALESQDCVEQLLKNMFDGDRTESCLVSGTQVLLTLLETRRVG-------------
------TEGLVDSFSQGLERS-YTVSSSVLHGIEPRLKDFHQLLLNPPKKKAILTTIGVL
EEPLGNARLHGARLMAALLHTNTPSINQ

ENSGT00390000009899_2_Linker_0_6 (569, 569)

PF04499 // ENSGT00390000009899_2_Domain_6 (569, 744)

ELCRLNTMDLLLDLFFKYTWNNFLHFQVELCI
AAILSHAAREDRTEASGSESRA--EPLHENG---NRSLETPQP-PASLPDNTMVTHLFQK
CCLVQRILEAWEANDHTQAAGGMRRGNMGHLTRIANAVVQNLERGPVQTHISE--VIRGL
PADCRGRWESFVEETLTETNRRNTVDL----------------------------AFSDY
QIQQMAASFVDQFGFNDEEFADQDDNINAPFDRIAEINFNIDADE--DSPSAALFEACCS
DRIQPFDD------------EDEDIWEDSDTRCATRVMARARFGAPHASDSCSKNGPERG
GQDGKASSEAHGD-----------APGAGAPLAPGKKEAP-TVEGDSE-GAMWTAVFDEP
ANST--PTAPGVVKDVGSSVWAAGT----SAPEEKGWAKFTDFQPFCCSESG---PRCSS
PVDTERSRAEGSRSQGPEKA--------FSPASPCAWNVCVTRKAPLLASDSSSSGGSNS
-EDYQ-----KAASAVDAVSRSPGREAPPRPTGAR-TEEA----------------VGRA
ECA-NSRLLDPAC--PAPKEVTAAPAV--APPPEAAVAITTALSKAGPAIPSPAVSSAVA
VAVPLGPIMAVTTAPA--------MVATLGTVTKDGKRDAP-PEGAALNGPV

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MFWK
FDLNTTSHVDKLLDKEHVTLQELMDEDDILQECKAQNQKLL-DFLCRQQCMEE---LVSL
ITQDPPLDMEEKVRFKYPNTACELLTCDVPQISDR-LGGDESLLSLLYDFLDHEPPLNPL
LASF--FSKTI

PF04499 // ENSGT00390000009899_2_Domain_0 (312, 569)

GNLIARKTEQVITFLKKKDKFISLVLKHIGTSALMDLLLRLVSCVEPAG
LRQEVLHWLNEEKVIQRLVELIHPSQDEDRQSNASQTLCDIVRLGRDQGSQLQEAL-EPD
PLLT-ALESQDCVEQLLKNMFDGDRTESCLVSGTQVLLTLLETRRVG-------------
------TEGLVDSFSQGLERS-YAVSSSVLHGIEPRLKDFHQLLLNPPKKKAILTTIGVL
EEPLGNARLHGARLMAALLHTNTPSINQ

ENSGT00390000009899_2_Linker_0_6 (569, 570)

E

PF04499 // ENSGT00390000009899_2_Domain_6 (570, 736)

LCRLNTMDLLLDLFFKYTWNNFLHFQVELCI
AAILSHAAREERTEASGSESRV--EPPHENG---NRSLETPQP-AASLPDNTMVTHLFQK
CCLVQRILEAWEANDHTQAAGGMRRGNMGHLTRIANAVVQNLERGPVQTHISE--VMRG-
--DCRLRLPSASQQVLTALTVRDPV-AVSTHHLHSSSEDEDIEGAFPNELSLQQ-AFSDY
QIQQMTANFVDQFGFNDEEFADQDDNINAPFDRIAEINFNIDADE--DSPSAALFEACCS
DRIQPFDD-----------DEDEDIWEDSDTRCATRVMARARFGAPHASESCSKNGPERG
GQDGKASLEAHRD-----------APGAAAPPAPRKKEAP-PVEGDSE-GTMWTAVFDEP
ANST--PTAPGVVRDVGSSVWAAGT----SAPEEKGWAKFTDFQPFCCSESG---PRCSS
PVDTEGSHAEGSRSQGPEKA--------FSPASPCAWNVCVTRKAPLLATDSSSSGGSDS
EDGDQ-----KAASAMDAVSRGPGREAPPLPTAAR-TEEA----------------VGRV
GCA-DGRLLSPAC--ATPKEVTAAPAV--AVPPEATVAITTALSKAGPAIPTPAVSSAVA
TAVPLGPIMAVTAAPA--------MVATLGTVTKDRKTDAP-PEGAALNGPV

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------YPNTACELLTCDVPQISDR-LGGDESLLSLLYDFLDREPPLNPL
LASF--FSKT

PF04499 // ENSGT00390000009899_2_Domain_0 (311, 745)

IGNLIARKTEQVIMFLKKKDKFISLVLTHIGTSALMDLLLRLVSCVEPAG
LRQEVLHWLNEEKIIQRLVELIHPSQDEDXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXX
XXXX-XXXX------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------X--X-
-XX---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKKAILTTIGVL
EEPLGNARLHGARLMAALLHTNTPSINQELCRLNTMDLLLDLFFKYTWNNFLHFQVELCI
AAILSHAAREERAEAGGPESRV--EPPHGNGN-GN--RSTEAPPAAAPPENIMVTHLFQK
CCLVQRILEAWEANDRTXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXL
PADCRGRWESFVEETLTXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXAFSEYQIQQMTANFVDQFGFNDEEFADQDDNINAPFDRVAEIN

PF04499 // ENSGT00390000009899_2_Domain_4 (311, 745)

IGNLIARKTEQVIMFLKKKDKFISLVLTHIGTSALMDLLLRLVSCVEPAGLRQEVLHWLNEEKIIQRLVELIHPSQDEDXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXX-XXXX------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------X--X--XX---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKKAILTTIGVLEEPLGNARLHGARLMAALLHTNTPSINQELCRLNTMDLLLDLFFKYTWNNFLHFQVELCIAAILSHAAREERAEAGGPESRV--EPPHGNGN-GN--RSTEAPPAAAPPENIMVTHLFQKCCLVQRILEAWEANDRTXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXLPADCRGRWESFVEETLTXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXAFSEY
QIQQMTANFVDQFGFNDEEFADQDDNINAPFDRVAEINFNIDADE--DSPSTALFEACCS
DRIQPFDD-----------EEEDDIWQGKEVHCATRGTARARFGAPHVSESHS-IDLEHR
GRDGKTGSETDRDT-----------SREGTPPAPVKNEVL-PMEESEXXXXXXXXXXXXX
XXXX--X-XXXXXXXXXXXXXXXXXX----XXXXXXXXXXXXXXXXX--XXX---XXXXX
XXXXXXXXXXXXXXXXXXXXXXQASCFAVGPASPCAWNVCVTRKAPLVASDSSSSGGSDS
EEDEQ-----KAASTLEAVSRGPGRETPLLPRTVEA-------------------VVGRA
DHT-DSRQPDPVC--PAPAEVNTALAMA----------TTTTLSKAGSPV---PAASAMA
VEVPPGPIMAVTTAAPA-------IVAALETVTKDSRTDSP-PAGAALNGPV

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MFWK
FDLNTTSHVDKLLDKEHVTLQELMDEDDILQECKAQNQKLL-DFLCRQQCMEE---LVSL
ITQDPPLDMEEKVRFKYPNTACELLTCDVPQISDR-LGGDESLLSLLYDFLDCEPPLNPL
LASF--FSKTI

PF04499 // ENSGT00390000009899_2_Domain_0 (312, 569)

GNLIARKTEQVITFLKKKDKFISLVLKHIGTSALMDLLLRLVSCVEPAG
LRQEVLHWLNEEKVIQRLVELIHPSEDEDRQSNAAQTLCDIVRLGRDQGSQLQEAL-EPD
PLLT-ALESQDCVEQLLKNMFDGDRTESCLVSGTQVLLTLLETRRVG-------------
------TEGLVDSFSQGLERS-YAVSSSVLHGIEPRLKDFHQLLLKPPKKKAILTTIGVL
EEPLGNARLHGARLMAALLHTNTPSINQ

ENSGT00390000009899_2_Linker_0_6 (569, 569)

PF04499 // ENSGT00390000009899_2_Domain_6 (569, 744)

ELCRLNTMDLLLDLFFKYTWNNFLHFQVELCI
AAILSHAAREERTEASGSDSRV--EPPHENE---NRSLETPQL-ATCSPDNTMLTHLFQK
CCLVQRILEAWEANDHTQAAGGMRRGNMGHLTRIANAVVQNLERGPVQTHISE--VIRGL
PADCRGRWESFVEETLTETNRRNTVDLVSTHHLHSSSEDEDIEGAFPNELSLQQ-AFSDY
QIQQMTANFVDQFGFNDEEFADQDDNINAPFDRIAEINFNIDADE--DSPSAALFEACCS
DRIQPFDD-----------DEDEDIWEDSDTRCATRVMARARFGAPHASESCSKNGLECR
SQDRKAS-SVDGD-----------VPGAHGPPAPGKNEAP-TVEGDSE-GATWTAVFDEP
ANLT--PMAPGVVRDVGSSVWAAGT----SAPEEKGWAKFTDFQPFCCSESG---PRCSS
PVDTECSHAEGSRSQGPEKV--------FSPASPCAWNVCATRKAPLLASDSSSSGGSDS
EDDDQ-----KAASAAEAVSRGPGWEAPALPSVTR-TEEA----------------VSRA
ECA-DSKLLDPAC--PVPKEVIAAPAV--AAPPKATVAT-TAVSKAGPTIATPAVSSAVA
VAAPLGPIMAVTTAPA--------MVATLGTVTKDGKTDAP-PEGAALNGPM

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MFWK
FDLNTTSHVDKLLDKEHVTLRELMDEDDILQECKAQNQKLL-DFLCRQQCMEE---LVSL
VTQDPPLDMEEKVRFKYPNTACELLTCDVPQISDR-LGGDGRLLGLLCDFLGREPPLNPL
LASF--FSKTI

PF04499 // ENSGT00390000009899_2_Domain_0 (312, 569)

GNLIARKTEQVITFLKKKDKFISLVLKHIGTSALMDLLLRLVSCVEPAG
LRQEVLQWLDEERIIQRLVELIHPSQDEDKQSNASQTLCDIVRLGRDQGSQLQEAA-EPD
PLLA-TMESQECVEQLLRNMFDEDQTESCLVSGTQVLLTLLETRRAGT------------
-------EGLVDSFSQGLERS-YVVSSSVLQGIEPRLKDFHQLLLNPPKKEAILTTIGVL
EEPLGNARLHGARLMAALLHTNTPNINQ

ENSGT00390000009899_2_Linker_0_6 (569, 569)

PF04499 // ENSGT00390000009899_2_Domain_6 (569, 744)

ELCRLNTMDLLLDLFFKYTWNNFLHFQVELCI
AAILSHAAREERADASGSESKV--EPLPGNL---NGNLETPQP-AAGLPENMMVTHLFQK
CCLVQRILEAWEANDHTQAAGGMRRGNMGHLTRIANAVVQNLERGPVQTHIRE--IIRGL
PADCRGRWESFVEETLTETNRRNTVDLVSTHHLHSSSEDEDIEGAFPNELSLQQ-AFSEY
QIQQMTANFVDQFGFNDEEFADQDDNINAPFDRIAEINFNIDAEE--DSPSAALFEACCS
DRIQPFDDD----------E-EEDIWEDKETRCVTRAMARARFGAPQASESCSKNGLEHK
GRDGKVHLEADRE-----------TPGAGTPTVPVSNEGA-PTEADSEAGTAWTAVFDEP
VNAT--PTAPGVVKDVGSSVWAASA----LAPEERGWAKFTDFQPFCCSESG---PRCSS
PVDTEHSHAEGGRSQDLEK--------AFGPASPCAWNVCVTRKAPLVVSDSSSSGGSDS
EDDEK------AAGTMETMNRGPSQEAPLLPTVAR-TEEAVV---------------SRA
-ESTDSTLPDPAR--PAPEEVTTALAV--AAPPET--TTTTAPSKAGPSVAPTAVSSAVA
VAVPPGPIVAV----------------PLGTVTKDRKTDAL-PGGAALNGPV

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MFWK
FDLNTTSHVDKLLEKEDVTLHELMDEDDILQECKAQNRKLL-DFLCKQQCMEE---LVSL
ITHDPPLDMEEKVRFKYPNTACELLTSDVPQINDK-LGGDETLLNILYDFLDHEPPLNPL
LASF--FSKTI

PF04499 // ENSGT00390000009899_2_Domain_0 (312, 565)

GNLIARKTEQVITFLKKKDQFISLVLKHIDTSAMMDLLLRLISCVEPAA
LRQEVLNWLNEENVIERLVQLIHSSQDEDRQSNASQTLCDIIRLSRDQGSQTQEIS-EPD
PLLT-ALESQECVEQLLKNMFDGDVTENCLVNGTQILLTLLETKEI--------------
-------WGLVDSFSQGFERS-YTVNSSILHGIEPWLKDFHQLLLTPPKKMSILTTIGIL
EEPLGNARLHGARLIAALLHTNTP

ENSGT00390000009899_2_Linker_0_6 (565, 566)

S

PF04499 // ENSGT00390000009899_2_Domain_6 (566, 744)

INQELCRLNTMDLLLDLFFKFTWNNFLHFQVELCV
AAILSHSAREGGMLTKEADSRE--DLPNGNGS-----LEKTEC-AEVTSENVMVTHLFQK
CCLVQRILDAWEANDRIQAEGGMRRGNMGHLTRIANAVVQNMEKGPIQTQISS--FIKEL
PEDCRGRWESFVEETLPETNRRNTVDL----------------------------AFSEY
QIQQMTANFVDQFGFNDEEFADQDDNINAPFDRIAEINFTIDADD--DSPNASLFEACCS
DRIQPFDDN----------EEEEDIWEDKEVNYATQAKSRTRFGASHTSEYSPQSNLENG
DQDGSEDSEEEDG-----GDDGPRLP---ERTSSSNISLQ-GDLDSSE-GSGWTAVFDEP
VNSK--PPPSGVAMDIGSRVWDAAAAADTCTSEEKGWAKFTDFQSFCCSESG---PRCSS
PVDTGSSTSEGKSKQGQDKTF--------SPAAPCVWNVCVARKAPLVASDSSSSGGSDS
EDEEEE-EEKKAGVVTETVGPGPGQEGLKPTTEAK-AEISVI-TSTEESPGTPK--ATVS
ERGVTGAPQQPSLQPLSPATVISAAAATAAVPTAA---TTAVLS--------AA-TTAVL
TAVP---AAATTVAATTVAATTVAATAALETVMRDRKEEAPPSPEATLNGPA

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------

PF04499 // ENSGT00390000009899_2_Domain_0 (322, 569)

VITFLKKKEKFISLMLKHIGTSALMDLLLRLVSCVEPVG
LRQEVLYWLNEEKIIQRLVELIHPHQDEDRQSNASQALCDIIRLGRDQGSQLQEAV-EPD
PLLI-TLESQDCVEQLLKNMFDGDQMESCLVSGMQVLLALLEPRRVGT------------
------EG-LVDSFSQGLERS-YSVNSSILHGIEPRLKNFHQLLLHPPKKKAILTTIGVL
EEPLGNARLHGARLMAALLHTNTPSINQ

ENSGT00390000009899_2_Linker_0_6 (569, 569)

PF04499 // ENSGT00390000009899_2_Domain_6 (569, 744)

ELCRLNTMDLLLDLFFKYTWNNFLHFQVELCI
AAILSHAAREEPAEASGSNGKV--EPLQGSGD-GAGKPETPQS-ITSLPENTMVTHLFQK
CCLVQRILEAWEANDHTQAAGGMRRGNMGHLTRIANAVVQNLEQGPVQTHISE--VIQGL
PADCRGRWESFVEETLMETNRRNTVDL----------------------------AFSEY
QIQQMTANFVDQFGFNDEEFADQDDNINAPFDRIAEINFNIEADE--DSPSAALFEACCS
DRIQPFDD-----------EEEEDIWEDEETRCTARVMARARFGAPHVSENYSKNSLEHG
VQDRKTGLAAARN-----------MPGLTTPSSPTQKEGP-RPESDSE-GTTWTAVFDEP
VNPM--SAAPGAARDVGSSVWAAGP----SAPEEKGWAKFTDFQPFCCSESG---PRCSS
PVD--HSHAEGGQSPGPEKAF--------GPTSPCAWNVCVTRKAPLVASDSSSSGGSDS
EDDEK------AAGAVEAVCTGHGGKASTLP---R-TEEA---------------AASRA
ECT-ESTVLAPVC--PASPEVIISPAV--ATT---------VPSEAGPRPASIVVSSSVA
AAVPPGPVMAVTTAAPA-------TVATLETMTKDRKTDAL-PEGAALNGPV

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MFWK
FDLNTTSHVDKLLDKEHVTLQELMDEDDILQECKAQNRKLL-DFLCRPQCMEE---LVNL
ITQDPPLDMEEKVRFKYPNTACELLTCDVPQISDR-LGGDESLLNLLYDFLDQEPPLNPL
LASF--FSKTI

PF04499 // ENSGT00390000009899_2_Domain_0 (312, 569)

GSLIARKTEQVIMFLKKKDKFISLVLKHMGTSALMDLLLRLVSCVEPMG
LRQEVLHWLNEEKTIQRLVELIHPHQDEDKQSNASQALCDIVRLSRDQGSQLQETL-EPD
PLLT-ELESQDCVEQLLKNMFDGDQTESCLVSGMQVLLALLEPRRAGT------------
-------EGLVDSFSQGLEGS-HTVSSSVLNGIEPRLKDFHQLLLNPPKKKAILTTIGVL
EEPLGNTRLHGARLMAALLYTNTPTINQ

ENSGT00390000009899_2_Linker_0_6 (569, 569)

PF04499 // ENSGT00390000009899_2_Domain_6 (569, 744)

ELCRLNTMDLLLDLFFKYTWNNFLHFQVELCI
AAILSHAAREERAEAAGSKRRV--EPPQGIRN-GNRGLETPQP-VASLPENTMVTHLFQK
CCLVQRILEAWEANDHTQAAGGMRCGNMGHLTRIANAVVQNLEQGPVQTHISE--IIQGL
PADCRGRWESFVEETLTETNRRNTVDLVSTHHLHSSSEDEDIEGAFPNELSLQQ-AFSEY
QIQQMTAHFVDQFGFNDEEFADQDDSINAPFDRIAEINFNIDADP--DSPSAALFEACCS
DRIQPFDD-----------E-EEDIWEDEETRSTARVMARARFGAPHCSESCSKNGLEHR
GQDRKADSEADSNK-----------PGAATPLALLQNEGF-SSEVNSE-GATWTAVFDEP
VNPT--APVPGAARDVGSSVWVAGV----SAPEEKGWAKFTDFQPFCCSESG---PRCSS
PVDTDHSHAESGQTPGPEKAF--------TSASPCAWNACVARKAPLVASDSSSSGGSDS
EDEEK------AAGTVETVSSGPGQEAPPPPRMED--------------------AAGRA
EYVDSSTPPDPAC--PVPSKVTSALAM--AVSPEAT-MATPALDKASPPTATPAVSTAVV
VAIPAGPIMEVTTVPA--------TVAALGTVTKDRETDAP-PEGAALNGPV

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----

PF04499 // ENSGT00390000009899_2_Domain_0 (366, 565)

LQWLNEARIIQRLVELIHSSQDEDRQSNASQTLSALSGLFSNLGSQREEWD-LPF
ALLTPCVPRQECVEQLLRNMFDAEQSETCFVNGTQVLLTLLEW-RSGV------------
-------KGLMDSYTQGFERS-YTVSNSILHGIQPRLKDFHQLLLHPPKKPAILTTLGVL
EEPLGNARLHGSRLIAALLHTNTP

ENSGT00390000009899_2_Linker_0_6 (565, 566)

S

PF04499 // ENSGT00390000009899_2_Domain_6 (566, 744)

INQELCRLGTMDLLLDLFFKYTWNNFLHFQVELSI
AAILSHSVHEGKPSPGEPGSKE--EAPSGNAAPEPAAPTEPSGPPAGATENVMVTHLFQK
CCLVQRILDAWEANDKIQAEGGRRRGNMGHLTRIANAVVHNMEKGPMQAQISD--FIKEL
PEDCRGRWESFVEETLTETNRRNTVDLVSTHH-HSSSEDEDIESAFPNELTLQQGAFSEY
QIQQMTANFVDQFGFNDEEFADQDDNINAPFDRIAEINFNIDADD--DSPNASLFEACCN
ERIQQFDDN----------EEEEDIWEEKDISYATQVKSRTRGSTEDVPGNFRW------
----SPRPEMMVSMAGGCY-IPWNVPGRGCWVLLPLRLG--WNQAVVSLGAGWTAVFEP-
---A--GPTPPVAMDVGSSVWDSAAP-PSSAPEEKGWAKFTDFQPFCCSESS---PRCSS
PVDTESGGTDRTPAQGQDKNS-------SAAASPCVWNACGTRKAPLVALDSSSSGSSES
DDDD--------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MFWK
FDLNTTSHVDKLLDKEDVSLEELMDEDDVLQECKAQNRRLL-DFLCQQQCMEQ---LLAL
ITHEPPLDMDEKVRFKFDDPSICLLTSDVPQINDK-LGGDETLLNILYDFLEHEPPLNPL
LASF--FSKTI

PF04499 // ENSGT00390000009899_2_Domain_0 (312, 565)

GNLIARKTEQVISFLRKKDKFLSLVLKHIDTSAMMDLLLRLISCVEPTA
LRQDVLNWLNEARIIQRLVELIHSSQDEDRQSNASQTLCDIIRLSRDQSTQLQDVP-EPD
PLLT-ALESQECVEQLLRNMFDGEQSETCIVNGTQVLLTLLETRRAGV------------
-------EGLMDSYTQGFERS-YTVSSSILHGIEPRLKDFHHRLAPAPQKAAILTTLGVL
EEPLGNARLHGARLVAALLHTNTP

ENSGT00390000009899_2_Linker_0_6 (565, 566)

G

PF04499 // ENSGT00390000009899_2_Domain_6 (566, 744)

INRELCRLGTMELLLDLFFKYTWNNFLHFQVELSI
AAILSHSAHEGKRSPGEQEQEQ--GQGQEQGRGPPEEQENPGISALGNAESALSLQLFQK
CCLVQRILDAWEANDKIQAEGGRRRGNMGHLTRIANAVVHNMEKGPMQAQISD--FIKEL
PEDCRGRWESFVEETLTETNRRNTVDLVSTHHLHSSSEDEDIESAFPNELTLQQ-AFSEY
QIQQMTANFVDQFGFNDEEFADQDDNINAPFDRIAEINFNIDADD--DSPNASLFEACCN
ERIQQFNDT----------EEEEDIWEEKEISYAAQVKARTRFGASQTSESS-KSDLENG
VSGAAPTHFEANSLSEGHMIEDPGSATALTPQNPALDLQ--CQPGCALPGAGWTAVFEP-
---A--SPTPPVAMDVGSSVWDSAAP-QSSAPEEKGWAKFTDFQPFCCSESG---PRCSS
PVDTEGGTD-RSPAQGQDKNC-------E-------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MFWK
FDLNTTSHVDKLLDKEHVTLQELMDEDDILQECKAQNQKLL-DFLCRQQCMEE---LVSL
ITQDPPLDMEEKVRFKYPNTACELLTCDVPQISDR-LGGDENLLNLLHDFLDREPPLNPL
LASF--FSKTI

PF04499 // ENSGT00390000009899_2_Domain_0 (312, 569)

GNLIARKTEQVIIFLKKKDKFISLVLKHMGTSALMDLLLRLVSCVEPVG
LRQEVLHWLNEEKIIQRLVELIHPHQDEDRQSNASQALCDIIRLGRDQGSQLQEAV-EPD
PLLT-ALESQDCVEQLLKNMFDGDQTESCLVSGMQVLLALLEPRRVGT------------
------EG-LVDSFSQGLERS-YSVSSSILQGIEPWLKNFHRLLLNPPKKKAILTTIGVL
EEPLGNARLQGARLMAALLHTNTPSINQ

ENSGT00390000009899_2_Linker_0_6 (569, 569)

PF04499 // ENSGT00390000009899_2_Domain_6 (569, 744)

ELCRLNTMDLLLDLFFKYTWNNFLHFQVELCI
AAILSHAAREEQAEASGSDGKV--EPLQGSGD-GNGKLETPQP-IASLPENTMVTHLFQK
CCLVQRILEAWEANDHTQAAGGMRRGNMGHLTRIANAVVQNLEHGPVQTHISE--VIRGL
PADCRGRWESFVEETLMETNRRNTVDL----------------------------AFSEY
QIQQMTANFVDQFGFNDEEFADQDDNINAPFDRIAEINFNIEADE--DSPSTALFEACCS
DRIQPFDD-----------E-EEDIWEDEETRCTARVMARARFGAPHVSENYSKNGLEHG
GQDRKAGSVVARN-----------VSGLATRSASAQKEGP-HSENDSE-GAAWTAVFDEP
INQM--SAAPGAARDVGSSVWTTGP----SAPEEKGWAKFTDFQPFCCSESG---PRCSS
PVDMDCSHAEGGQSAGPEKAF--------GPTSPCAWNMCVTRKAPLVASDSSSSGGSDS
EDDEK-------AGTVEAVSTGHGEAS--RL---S-RTEA---------------AVGRV
ECA-DSIVPAPAC--PASSEVTTTPAV--ASP---------APSKAGPPIATTAVSSTVA
IAVPPGPIMTITTAAPA-------IVATLETMTKDRKTDAP-PGGAALNGPV

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MFWK
FDLNTTSHVDKLLDKEHVTLQELMDEDDILQECKAQNQKLL-DFLCRQQCMEQ---LVSL
ITQEPPLDMEEKVRFKYPNTACELLTCDVPQISDR-LGGDESLLSLLYDFLDHEPPLNPL
LASF--FSKTI

PF04499 // ENSGT00390000009899_2_Domain_0 (312, 569)

GNLIARKTEQVITFLKKKDKFISLVLKHIGTSALMDLLLRLVSCVEPAG
LRQEVLHWLNEEKVIQRLVELIHPSEDEDRQSNAAQTLCDIVRLGRDQGSQLQEAL-EPD
PLLT-ALESQDCVEQLLKNMFDGDRTESCLVSGTQVLLTLLETRRIG-------------
------TEGLVDSFSQGLERS-YTVSSSVLHGIEPRLKDFHQLLLNPPKKKAILTTIGVL
EEPLGNARLHGARLMAALLHTNTPSINQ

ENSGT00390000009899_2_Linker_0_6 (569, 569)

PF04499 // ENSGT00390000009899_2_Domain_6 (569, 744)

ELCRLNTMDLLLDLFFKYTWNNFLHFQVELCI
AAILSHAAHEERTEASGSDSGA--EPPRENG---NRSLETPQL-ATSPPDSTMVTHLFQK
CCLVQRILEAWEANDHTQAAGGMRRGNMGHLTRIANAVVQNLERGPVQTHISE--VIRGL
PADCRGRWESFVEETLTETNRRNTVDLVSTHHLHSSSEDEDIEGAFPNELSLQQ-AFSDY
QIQQMTANFVDQFGFNDEEFADQDDNINAPFDRIAEINFNIDADE--DSPSAALFEACCS
DRIQPFDD-----------DEDEDIWEDSDTRCATRVTARARFGAPHASESCSKNSLECR
SQDRKAS-SGDGD-----------VPGTHAPPAPGKNEAP-PVEGDSE-GATWTAVFDEP
ANSM--PMAPGVVRDVGSSVWAAGT----SAPEEKGWAKFTDFQPFCCSESG---PRCSS
PVDTECSHAKGSRIQGPEKAS-QASCFAVSPASPCAWNVCATRKAPLLASDSSSSGGSDS
EDDDQ-----KAASATDAVSRGPGWEAPPLPTVTR-TEEA----------------VGRA
ECA-DSKLLDPAC--PMPKEVTAAPAV--AVPPEATVATTTALSKAGPAIATPAVSSAVA
VAAPLGPIMAVTAAPA--------MVATLGTVTKDGKTDAP-PEGAALNGPV

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MFWK
FDLNTTSHVDKLLDKEHVTLQELMDEDDILQECKAQNQKLL-DFLCRQQCMEE---LVSL
ITQDPPLDMEEKVRFKYPNTACELLTCDVPQISDR-LGGDESLLSLLYDFLDHEPPLNPL
LASF--FSKTI

PF04499 // ENSGT00390000009899_2_Domain_0 (312, 569)

GNLIARKTEQVITFLKKKDKFISLVLKHIGTSALMDLLLRLVSCVEPAG
LRQEVLHWLNEEKVIQRLVELIHPSQDEDRQSNASQTLCDIVRLGRDQGSQLQEAL-EPD
PLLT-ALESQDCVEQLLKNMFDGDRTESCLVSGTQVLLTLLETRRVG-------------
------TEGLVDSFSQGLERS-YTVSSSVLHGIEPRLKDFHQLLLNPPKKKAILTTIGVL
EEPLGNARLHGARLMAALLHTNTPSINQ

ENSGT00390000009899_2_Linker_0_6 (569, 569)

PF04499 // ENSGT00390000009899_2_Domain_6 (569, 744)

ELCRLNTMDLLLDLFFKYTWNNFLHFQVELCI
AAILSHAAREDRTEASGSESRA--EPLHENG---NRSLETPQP-PASLPDNTMVTHLFQK
CCLVQRILEAWEANDHTQAAGGMRRGNMGHLTRIANAVVQNLERGPVQTHISE--VIRGL
PADCRGRWESFVEETLTETNRRNTVDLVSTHHLHSSSEDEDIEGAFPNELSLQQ-AFSDY
QIQQMAASFVDQFGFNDEEFADQDDNINAPFDRIAEINFNIDADE--DSPSAALFEACCS
DRIQPFDD-----------DEDEDIWEDSDTRCATRVMARARFGAPHASDSCSKNGPERG
GQDGKASSEAHGD-----------APGAGAPPAPGKKEAP-TVEGDSE-GAMWTAVFDEP
VNST--PTAPGVVRDVGASVWAAGT----SAPEEKGWAKFTDFQPFCCSESG---PRCSS
PVDTERSRAEGSRSQGPEKA--------FSPASPCAWNVCVTRKAPLLASDSSSSGGSDS
-EDYQ-----KAASAVDAVSRSPGREAPPRPTGAR-TEEA----------------VGRA
VCA-NSRLLDPAC--PAPKEVTAAPAM--APPPEAAVAITTALSKAGPAIPSPAVSSAVA
VAVPLGPIMAVTTAPA--------MVATLGTVTKDGKRDAP-PEGAALNGPV

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MFWK
FDLNTTSHVDKLLEKEDVTLHELMDEDDILQECKAQNRRLL-DFLCRQQCMEE---LVGL
ITRDPPLDMEEKVRFKYPNTACELLTSDVPQINDK-LGGDETLLNILYDFLDHEPPLNPL
LASF--FSKTI

PF04499 // ENSGT00390000009899_2_Domain_0 (312, 563)

GNLIARKTEQVIVFLKKKDKFISLVLKHIDTSAMMDLLLRLISCVEPAS
LRQEVLNWLNEEKVIQRLVELIHSDQDEDRQSNASQTLCDIIRLSRDQSSQLQETS-EPD
PLLA-ALESQGCVEQLLKNMFDGDQTENCIVNGTQILLTLLETRRSGM------------
------EG-LADTFSQGPDRP-CAVSSSVLHGIEPRLKDFHQLLLHPPKRPAILTTIGVL
EEPLGNARLHGARLVAALLHTD

ENSGT00390000009899_2_Linker_0_6 (563, 566)

TPR

PF04499 // ENSGT00390000009899_2_Domain_6 (566, 744)

INQELCRLNTVDLLLDLFFKYTWNNFLHFQVELCI
AAILSHSAREGKATVISESENKE-EMPNGN----------VAPESADSTANVMVTHLFQR
CCLVQRILDAWEANDQAQAEGGMRRGNMGHLTRIANAVVQTVEKGPRQAQISE--FIKEL
PEDCRGRWESFVEETLTETNRRNTVDLVSTHHLHSSSEDEDIESAFPNELSLQQ-AFSEY
QIQQMTANFVDQFGFNDEEFADQDDNINAPFDRIAEINFSVEADD--DSPNASLFEACCN
DQIQPFDDNVEEEEAVAEEEEEEDIWDDKEMSYTAQGKSRTRFGASQGSEGSSKSDLENG
DREGNADSEEERE-----PQRPASVPARKTGGSPGPAAGT-KEADSCG-GSGWTAVFDEP
VNSK--PPPPCVAMDVGSSVWDAAAQ-ESSAPEEKGWAKFTDFQPFCCSESG---PRCSS
PVDTKNSNSEGNLKQNQEACPRALSSPAVGAGSPCAWNVCVARKAPLVASDSSSSGGSDS
EEEEE-----DRAGPASGRDAPQPPWNAAQPTPDA-RGEVDVPSRCEGM------GTGGG
K------GAGPGS-----------------------------------------------
----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MFWK
FDLNTTSHVDKLLDKEDVTLRELMDEDDILQECKAQNRKLL-DFLCRQQCMEE---LVSL
ITQDPPLDMEEKVRFKYPNTACELLTCDVPQINDR-LGEDETLLNLLYDFLDHEPPLNPL
LASF--FSKTI

PF04499 // ENSGT00390000009899_2_Domain_0 (312, 565)

GNLIARKTEQVIVFLKRKDKFISLVLKHIGTSALMDLLLRLISCVEPAG
LRQEVLHWLNEEKIIQRLVELIHPSQDEDRQSNASQTLCDIVRLGREQGNQLQEAP-EPD
PLLT-VLESQDCVEQLLTNMFDGDQTESCLVNGTQVLLTLLETRRAGT------------
------EG-LVDSFSQGLERL-CTVSGSILHGIEPRLKDFHQLLLSPPKKKAILTTIGVL
EEPLGNARLHGARLMAALLHTNTP

ENSGT00390000009899_2_Linker_0_6 (565, 566)

S

PF04499 // ENSGT00390000009899_2_Domain_6 (566, 744)

INQELCRLNTMGLLLDLFFKYTWNNFLHFQVELCI
AAILSHTAQEDRAEASGPQSRV--EPLPGNRD-----SEAPQP-AAGHPENTMVTHLFQK
CCLVQRILEAWEANDHTQAAGGMRRGNMGHLTRIANAVVQNLERGPMQTHISE--VIRGL
PADCRGRWESFVEETLRETNRRNAVDL----------------------------AFSEY
QVQQMTATFVDQFGFNDEEFADQDDSVNAPFDRIAEINFSIDADE--DSPSAALFEACCS
DHIQPFDD-----------DEDDDIWEDKETHCTTRVTARARFGGPHTSESCSKNSLEPG
GQDGKEGSEADGD-----------AARAGTPPATPQKEGP-RMEGDPE-GATWT-MFDEP
VSST--TPAPGVAMDVGSSVWAASTP-SASALEEKGWAKFTDFQPFCCSESG---PRCSS
PVDRGRGDAQGGPNQGRERTV--------GPASPCAWNVCVASKASLVASNSD-------
-KDEQ-----KVVGALEAVSIVPGREASPLPTSAP-SLESVKFTGCASSQRSFPCLPHRA
ECG-ASMLPDLAS--PAPAEVTSAPAM--AGP-------------------TPAVSPVLA
MAIPPGPMVAITTTAPPTASPAVSTVATLGSVTKDRKMDMPPPTGATLNGPV

------------------------------------------------------------
------------------------------------------------------------
-------------------MAWPGGGASPGAQMIGACGQGGLLALQRRKESFVAVTMFWK
FDLNTTSHVDKLLDKEDVTLRELMDEDDVLQECKAQNQKLL-GFLCRQQCMEE---LVSL
ITRDPPLDMEEKVRFKYPNTACELLTCDVPQINDR-LGGDETLLNLLYDFLDHEPPLNPL
LASF--FSKTI

PF04499 // ENSGT00390000009899_2_Domain_0 (312, 565)

GNLIARKTEQVIQFLKKKDGFVGLVLKHLGTSALMDLLLRLVSCVEPAG
LRRDVLHWLNGEKIIQRLVQLIHPSQDEDRQSNASQTLCDIIRLGREQGSQLQEAP-EPD
PLLA-VLESQDCVERLLKNMFDGDRTESCLVSGTQVLLTLLETRRAGT------------
------EG-LVDSFSQGLEGL-CTVSSSVLHGIEPRLKDFHQLLLSPPKKEAILTTIGVL
EEPLGNARLHGARLMAALLHTNTP

ENSGT00390000009899_2_Linker_0_6 (565, 566)

G

PF04499 // ENSGT00390000009899_2_Domain_6 (566, 744)

INRELCRLDTMGLLLDLFFKYTWNNFLHFQVELCI
AAILSHAAREDRAGASGPDSGV--ELLPGNGD-----PETPQP-AASCPENTMVTHLFQK
CCLVQRILEAWEANDHAQAAGGTRRGNMGHLTRIANAVAQNLEKGPVRAHISD--VLRGL
PADCRGRWDNFVEETLAETNRRNAVDLVSTHHLHPSSEDEDMEGVFPNELSLQQ-AFSEY
QVQQMTATFVDQFGFNDEEFADQDDSVNAPFDRIAEINFSIDADE--DSPSTALFEACCG
DRIQPFDD-----------DEEEDIWEDEGTHRAARVTARARFGGPHTSESCSKNGLQRG
GQDRKEGLEADKD-----------AARARASLASTQKEGP-RLEGGSEEGTSWA-VFDEP
VNSP--VPAPGVAVDVGSSVWAASTH-SPSTSEEKGWAKFTDFQPFCCSESG---PRCSS
PVDTGHGDTQEGPNQGPERAR---------PASPCAWSACVTRKAPLVVSDNS-------
-EDQQ-----KTAGALEAISLGPSREAPPPSASVP----------------------RA-
-ECAGSLLSDPTS--PAPAEATFTLAV--AVPAEAAVAATPAPSKAGPTPATMA------
--GPPGPAVAVTTAAPA-----TCTAAMLGTVTKDKQTDSPPPAGAALNGPM

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MFWK
FDLNTTSHVDKLLDKEDVTLHELMDEDDILQECKAQNRKLL-DFLCQQHCMEE---LVNL
ITHEPPVDMDEKVRFKYPNTACELLTSDVPQINDK-LGGDETLLNILYDFLDHEPPLNPL
LASF--FSKT

PF04499 // ENSGT00390000009899_2_Domain_0 (311, 745)

IGNLIARKTEQVIAFLRKKDKFISLVLKHIDTSAMMDLLLRLISCVEPAT
LRQEVLNWLNEAKIIQRLVELIHSSQDEDRQSNASQTLCDIIRLSRDQSNQLQDIP-EPD
PLLT-ALESQECVEQLLKNMFDGEQTENCIVNGTQVLLTLLETRRSGV------------
-------EGLMDSYTQGFERS-YTVNSSILHGIEPRLKDFHQLLLSPPKKTAILTTIGVL
EEPLGNARLHGSRLIAALLHTNTPSINQELCRLSTMNLLLDLFFKYTWNNFLHFQVELSI
AAILSHSVQEGKTTTNDLESK-------EEVLNGNVATENL-EAPENNTENIMVTHLFQK
CCLVQRILDAWEANDKIQAEGGMRRGNMGHLTRIANAVVQNMEKGPMQTQISE--FIKEL
PEDCRGRWESFVEETLMETNRRNTVDLVSTHHLHSSSEDEDIESAFPNELSLQQ-AFSEYQIQQMTANFVDQFGFNDEEFADQDDNINAPFDRIAEIN

PF04499 // ENSGT00390000009899_2_Domain_4 (311, 745)

IGNLIARKTEQVIAFLRKKDKFISLVLKHIDTSAMMDLLLRLISCVEPATLRQEVLNWLNEAKIIQRLVELIHSSQDEDRQSNASQTLCDIIRLSRDQSNQLQDIP-EPDPLLT-ALESQECVEQLLKNMFDGEQTENCIVNGTQVLLTLLETRRSGV-------------------EGLMDSYTQGFERS-YTVNSSILHGIEPRLKDFHQLLLSPPKKTAILTTIGVLEEPLGNARLHGSRLIAALLHTNTPSINQELCRLSTMNLLLDLFFKYTWNNFLHFQVELSIAAILSHSVQEGKTTTNDLESK-------EEVLNGNVATENL-EAPENNTENIMVTHLFQKCCLVQRILDAWEANDKIQAEGGMRRGNMGHLTRIANAVVQNMEKGPMQTQISE--FIKELPEDCRGRWESFVEETLMETNRRNTVDLVSTHHLHSSSEDEDIESAFPNELSLQQ-AFSEY
QIQQMTANFVDQFGFNDEEFADQDDNINAPFDRIAEINFNIDADD--DSPNASLFEACCN
ERIQQFDDN----------EEEEDIWEEKEITYATQVKSRTRFGASQTSESSSKSDLENG
DHDGSVDSEEEEE--TEQQ-----VPPSSANSNKNNVSE--QKDSDSSEGSGWTAVF-EP
VNSK--PPTPCVAMDVGSSVWDSAAP-ENTTPEEKGWAKFTDFQPFCCSESG---PRCSS
PVDTESNDSEGNPKQSQDKNF-------S-AASPCVWNVCVTRKAPLVASDSSSSGGSDS
DEED-----DKADVVTETISTGSGQETIKLTVDAK-NEKAVFT-----------------
------------------------------------------------------------
----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MFWK
FDLNTTSHVDKLLDKEHVTLQELMDEDDILQECKAQNRKLL-DFLCRPQCMEE---LVNL
ITQDPPLDMEEKVRFKYPNTACELLTCDVPQISDR-LGGDESLLNLLYDFLDQEPPLNPL
LASF--FSKTI

PF04499 // ENSGT00390000009899_2_Domain_0 (312, 569)

GSLIARKTEQVIMFLKKKDKFISLVLKHMGTSALMDLLLRLVSCVEPMG
LRQEVLHWLNEEKTIQRLVELIHPHQDEDKQSNASQALCDIVRLSRDQGSQLQETL-EPD
PLLT-ELESQDCVEQLLKNMFDGDQTESCLVSGMQVLLALLEPRRAGT------------
-------EGLVDSFSQGLEGS-HTVSSSVLNGIEPRLKDFHQLLLNPPKKKAILTTIGVL
EEPLGNTRLHGARLMAALLYTNTPTINQ

ENSGT00390000009899_2_Linker_0_6 (569, 569)

PF04499 // ENSGT00390000009899_2_Domain_6 (569, 744)

ELCRLNTMDLLLDLFFKYTWNNFLHFQVELCI
AAILSHAAREERAEAAGSKRRV--EPPQGIRN-GNRGLETPQP-VASLPENTMVTHLFQK
CCLVQRILEAWEANDHTQAAGGMRCGNMGHLTRIANAVVQNLEQGPVQTHISE--IIQGL
PADCRGRWESFVEETLTETNRRNTVDLVSTHHLHSSSEDEDIEGAFPNELSLQQ-AFSEY
QIQQMTAHFVDQFGFNDEEFADQDDSINAPFDRIAEINFNIDADP--DSPSAALFEACCS
DRIQPFDD-----------E-EEDIWEDEETRSTARVMARARFGAPHCSESCSKNGLEHR
GQDRKADSEADSNK-----------PGAATPLALLQNEGF-SSEVNSE-GATWTAVFDEP
VNPT--APVPGAARDVGSSVWVAGV----SAPEEKGWAKFTDFQPFCCSESG---PRCSS
PVDTDHSHAESGQTPGPEKAF--------TSASPCAWNACVARKAPLVASDSSSSGGSDS
EDEEK------AAGTVETVSSGPGQEAPPPPRMED--------------------AAGRA
EYVDSSTPPDPAC--PVPSKVTSALAM--AVSPEAT-MATPARDKASPPTATPAVSTAVV
VAIPAGPIMEVTTVPA--------TVAALGTVTKDRETDAP-PEGAALNGPV

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MFWK
FDLNTTSHVDKLLDKEHVTLQELMDEDDILQECKAQNRKLL-DFLCRPQCMEE---LVNL
VTQEPPLDMEEKVRFKYPNTACELLTCDVPQISDR-LGGDERLLNLLYDFLDREPPLNPL
LASF--FSKTI

PF04499 // ENSGT00390000009899_2_Domain_0 (312, 569)

GNLIARKTEQVIMFLKKKDKFISLVLKHMGTSALMDLLLRLVSCVEPMG
LRQEVLHWLNEEKTIQRLVELIHPHQDEDRQSNASQALCDIVRLSRDQGSQLQETL-EPD
PLLT-ALESQNCVEQLLKNMFDGDHTESCLISGMQVLLALLEPRRAGT------------
-------EGLVDSFSQGLERS-HTVCSSVLNGIEPRLKDFHQLLLNPPKKKAMLTTIGVL
EEPLGNARLHGARLMAALLHTNTPSINQ

ENSGT00390000009899_2_Linker_0_6 (569, 569)

PF04499 // ENSGT00390000009899_2_Domain_6 (569, 744)

ELCRLNTMDLLLDLFFKYTWNNFLHFQVELCI
AAILSHAAREERAEAGGSKSRV--EPPKGSGN-GDRSLETPQP-VVSLPENTMVTHLFQK
CCLVQRILEAWEANDHTQASGGMRRGNMGHLTRIANAVVQNLERGPVQTHISE--VIQGL
PADCRGRWESFVEETLTETNRRNTVDLVSTHHLHSSSEDEDIEGAFPNELSLQQ-AFSEY
QIQQMTAHFMDQFGFNDEEFADQDDSINAPFDRIAEINFNIDADE--DSPSAALFEACCS
DRIQPFDD-----------E-EEDIWEDEETRSTARVTARARFGAPHSSESCTKNGLEHG
GQDRKSGSEADRNK-----------PGAPPPRALGQNEGF-SSEGNSE-GATWTAVFDEP
VNPT--APVPGAARDVGSSMWAAGT----SASEEKGWAKFTDFQPFCCSESG---PRCSS
PVDTDHRQAESGQSPGPEKAF--------SPASPCARNVYVTRKAPLVASDSSSSGGSDS
ADEEK------ATRTVETVSLGPGREEPPPPWMED--------------------DAGRA
ECVDSSTPPDPAC--PVPSKVTSSLAM--AVSPEAT-MTTPALDKASPPTATPSVSTAVF
VAIPAGPIVEVTTVPA--------TVSTLGTVTKVRETDAP-PEGAALNGPV

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MFWK
FDLNTTSHVDKLLDKEHVTLRELMDEDDILQECKAQNQKLL-DFLCRQQCMEE---LVSL
VTQDPPLDMEEKVRFKYPNTACELLTCDVPQISDR-LGGDGRLLGLLCDFLGREPPLNPL
LASF--FSKTI

PF04499 // ENSGT00390000009899_2_Domain_0 (312, 569)

GNLIARKTEQVITFLKKKDKFINLVLKHIGTSALMDLLLRLVSCVEPAG
LRQEVLRWLDEEKIIQSLVELIHPSQDEDKQSNASQTLCDIVRLGRDQGSQLQEAA-EPD
PLLA-TLESQDCVEQLLRNMFDEDQTESCLVSGTQVLLTLLETRRAGT------------
-------EGLVDSFSQGLERS-YVVSSSVLQGIEPRLKDFHQLLLNPPKKEAILTTIGVL
EEPLGNARLHGARLMAALLHTNTPSINQ

ENSGT00390000009899_2_Linker_0_6 (569, 569)

PF04499 // ENSGT00390000009899_2_Domain_6 (569, 744)

ELCRLNTMDLLLDLFFKYTWNNFLHFQVELCI
AAILSHAAREERADASGSESKA--EPLPGNT---NGNLETPQR-AAGFPENMMVTHLFQK
CCLVQRILEAWEANDHTQAAGGMRRGNMGHLTRIANAVVQNLERGPVQTHIRE--VIRGL
PADCRGRWESFVEETLTETNRRNTVDLVSTHHLHSSSEDEDIEGAFPNELSLQQ-AFSEY
QIQQMTANFVDQFGFNDEEFADQDDNINAPFDRIAEINFNIDADE--DSPSTTLFEACCG
DRIQPFDDD----------E-EEDIWEDKETRCVTRAMARARFGAPQPSESCSRNGLEHK
GQDGKVCLEVDRD-----------TSGAGTPTVPVSNEGA-PVEADSEAGTAWTAVFDEP
VNAT--PTAPGVVRDMGSSVWAASA----LAPEERGWAKFTDFQPFCCSESG---PRCSS
PVDTERSHAEGSRGQDLEKSS----CFAVGPASPCAWNVCVTRKAPLVVSDSSSSGGSDS
EDDEK------AAGAMDTMSRGPRDGGL--------------------------------
-----PGALDPAC--PTPEEVTTALAV--AAPLE-----TTAPSKAGPPVTPTAVSSAVA
VAVPPGPVMAA----------------TLGTVTKDRKTDAL-PGGAALNGPV

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MFWK
FDLNTTSHVDKLLDREQVTLQELMDEDDILQECKAQNRKLL-DFLCRPQCMEE---LVSL
ITQDPPLDMEEKVRFKYPNTACELLTCDVPQISDR-LGEDESLLSLLYDFLDQEPPLNPL
LASF--FSKTI

PF04499 // ENSGT00390000009899_2_Domain_0 (312, 569)

GNLIARKTEQVIAFLKKKDKFISLVLKHMGTSALMDLLLRLVSCVEPAG
LRQEVLHWLNEEKIIQRLVELIHPHQDEDRQSNASQALCDIVRLGRDQSSQLPEAL-EPD
PLLT-TLESQDCVEQLLKNMFDGEQTESCLVSGTQVLLALLEPRRAGT------------
------EG-LVDSFSQGLERP-HAVSSSVLHGIEPRLKDFHQLLLHPPKKKAILTTVGVL
EEPLGSARLHGARLVAALLHADTPSIHQ

ENSGT00390000009899_2_Linker_0_6 (569, 569)

PF04499 // ENSGT00390000009899_2_Domain_6 (569, 744)

ELCRLSTMDLLLDLFFKYTWNNFLHFQVELCI
AAILSHAAPEERAEAQGSQSRV--EPPQGSGN-GNRSLETHQP-IAKLPENTMVTHLFQK
CCLVQRILEAWEANDHAQAAGGMRRGNMGHLTRIANAVVQNLERGPVQTHISE--VIRGL
PADCRGRWESFVEETLTETNRRNTVDL----------------------------AFSEY
QIQQMTANFVDQFGFNDEEFADQDDNINAPFDRIAEINFSIDADE--DSPSAALFEACCS
DRIQPFDD-----------DEEEDIWEDEETRCTAQVVSRARFGAPHTSEHCSKNALERG
GQDRKAGSEADRT-----------APRAGILLPPAQNGGP-PSESASE-GAAWTAVFDEP
GNPT--TPAPRAVKDVGSSVWAAST----STPEEKGWAKFTDFQPFCCSESG---PRCSS
PVDVDHSHVEAGQSPDPGTSS--------GPASPCAWNVCVTGKAPLVTSDG--------
-EDEQ-----KVAGTMGTVSTGPGREGFLPP---R-TEAA---------------AVGRA
KCA-DSTPLGPAS--LEPSEATSTPTV--AT---------TVLDKASPPMAAPVVSPAVA
VSVPPGPTMVVPTAAPA-------TVATMATATKDRKTDAP-PEGAALNGPV

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MFWK
FDLNTTSHVDKLLDKEHVTLQELMDEDDILQECKAQNQKLL-DFLCRQQCMEE---LVSL
ITQDPPLDMEEKVRFKYPNTACELLTCDVPQISDR-LGGDESLLSLLYDFLDHEPPLNPL
LASF--FSKTI

PF04499 // ENSGT00390000009899_2_Domain_0 (312, 569)

GNLIARKTEQVITFLKKKDKFISLVLKHIGTSALMDLLLRLVSCVEPAG
LRQEVLHWLNEEKVIQRLVELIHPSQDEDRQSNASQTLCDIVRLGRDQGSQLQEAL-EPD
PLLT-ALESQDCVEQLLKNMFDGDRTESCLVSGTQVLLTLLETRRVG-------------
------TEGLVDSFSQGLERS-YTVSSSVLHGIEPRLKDFHQLLLNPPKKKAILTTIGVL
EEPLGNARLHGARLMAALLHTNTPSINQ

ENSGT00390000009899_2_Linker_0_6 (569, 569)

PF04499 // ENSGT00390000009899_2_Domain_6 (569, 744)

ELCRLNTMDLLLDLFFKYTWNNFLHFQVELCI
AAILSHAAREDRTEASGSESRA--EPLHENG---NRSLETPQP-PASLPDNTMVTHLFQK
CCLVQRILEAWEANDHTQAAGGMRRGNMGHLTRIANAVVQNLERGPVQTHISE--VIRGL
PADCRGRWESFVEETLTETNRRNTVDLVSTHHLHSSSEDEDIEGAFPNELSLQQ-AFSDY
QIQQMAASFVDQFGFNDEEFADQDDNINAPFDRIAEINFNIDADE--DSPSAALFEACCS
DRIQPFDD-----------DEDEDIWEDSDTRCATRVMARARFGAPHASDSCSKNGPERG
GQDGKASSEAHGD-----------APGAGAPLAPGKKEAP-TVEGDSE-GAMWTAVFDEP
VNST--PTAPGVVRDVGASVWAAGT----SAPEEKGWAKFTDFQPFCCSESG---PRCSS
PVDTERSRAEGSRSQGPEKAS-QASSFAVSPASPCAWNVCVTRKAPLLASDSSSSGGSDS
-EDYQ-----KAASAVDAVSRSPGREAPPRPTGAR-TEEA----------------VGRA
VCA-NSRLLDPAC--PAPKEVTAAPAM--APPPEAAVAITTALSKAGPAIPSPAVSSAVA
VAVPLGPIMAVTTAPA--------MVATLGTVTKDGKRDAP-PEGAALNGPV

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MFWK
FDLNATSHVDKLLEKEGVTLHELMDQDDILQECKAQNQKLL-DFLCRQQCMEE---LVHL
ISQDPPLDMEEKVRFKYPNTACELLTSDVPQINDK-LGGDETLLNLLYDFLNHEPPLNPL
LASF--ISKTI

PF04499 // ENSGT00390000009899_2_Domain_0 (312, 565)

GNLIARKTEQVIGFLKKKDQFISLVLRHLSTSATMDLLLRLASCVEPAS
LRQEVLHWLNEEMIIQRLVELVHPGQDEDRQSNASQTLCDIVRLGRDQSGQLQGPS-EPD
PLLA-VLESQGCVEQLLKNMFDGDWTESCLVSGTQVLLTLLETGRAGT------------
------EG-LADAFSQGLERA-HPVNSSVLHGIVPRLKDFHQLLLSPPKKQAILTTIGVL
EEPLGNARLHSARLVAALLHTSTP

ENSGT00390000009899_2_Linker_0_6 (565, 566)

S

PF04499 // ENSGT00390000009899_2_Domain_6 (566, 744)

INQELCRLSTLDLLLDLFFKYAWNNFLHLQVELCI
AAVLSPAAQEERAEAGEAASGG---------------AKTPQP-AAGRPEGTMVTHLFQK
CCLVQRILEAWEANDRTQPWGGLRSCSPGQTPRLWVSAHLKRARGAP---SRRASWLKGL
PEDCRRRWDSFVEDTLPEANRRNAVDLVST-HLHSSSEDEDIDGAFPQELSLQQ-AFSEY
QVQRMTASFVDQFGFNDEEFADQDDSVNMPFDRVAEINFHTDAED--DGPHASLFEACCG
DHIQPFDDP----------EDDDDLWEDRGPDGLARAVARARFGAPQAPKSCSKISPERG
Q-DGTGHAEATRAAPGG-GASPGRECSSPCPPATTQK-----------EGARRTAVLGEL
TSPV--PPAPTAAVDVGSGACPASAP-SASAPEEQGWAVLTDFPPCCCSEAG---PRCSS
PVDTHHVDAEGSGSQCPEAFS---------PAAPCAWSTRVPRKAPLVASDSSSSGGSDS
KDDAQS------ACCAEAVTRRKTAQNGILPAPAP-SAGAESPPTCPR---------GRR
V--------KSARAAPAPAEGTALPAVV--AP----------------------------
------------------------TAAPLGTATPDR------PTGAAVNGSV

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MFWK
FDLNTTSHIDKLLDKEHVTLQELMDEDDVLQECKAQNRKLL-DFLCRPQCMEE---LVNL
ITQDPPSDMEEKVRFKYPNTACELLTCDVPQISDR-LGGDENLLNLLYDFLDQEPPLNPL
LASF--FSKTI

PF04499 // ENSGT00390000009899_2_Domain_0 (312, 569)

GNLIARKTEQVIVFLKKKDKFTSLVLKHMGTSALMDLLLRLVSCVEPMG
LRQEVLHWLNEEKIIQRLVELIHPHQDEDRQSNASQALCDIVRLSRDQSSQLQETL-KPD
PLLV-ALESQDCVEQLLKNMFDGDQTESCLVSGMQVLLALLEPRRAGT------------
-------EGLVDSFSQGLERS-HAVSISVLNGIEPRLKDFHQLLLNPPKKKAILTTIGVL
EEPLGNARLHGARLMAALLYTNTPSINQ

ENSGT00390000009899_2_Linker_0_6 (569, 569)

PF04499 // ENSGT00390000009899_2_Domain_6 (569, 744)

ELCRLNTMDLLLDLFFKYTWNNFLHFQVELCI
AAILSHAAGEERAEAGGSESKV--EPPQGSGN-GNRSLETPQP-VASLPENTMVTHLFQK
CCLVQRILEAWEANDHTQAAGGMRRGNMGHLTRIANSVVQNLERGPVQTHISE--VIQGL
PADCRGRWESFVEETLTETNRRNTVDLVSTHHLHSSSEDEDIEGAFPNELSLQQ-AFSEY
QIQQMTAHFVDQFGFND-EFADQDDSVNAPFDRIAEINFNIDADE--DSPSTALFEACCS
DRIQPFDD-----------EEEEDIWEDEETCSTSRVMARARFGVPHSPESCSKNGVDYG
GQDRKAGSEADRNK-----------PGAATPLALEQNEGF-S-ESNSE-EAAWTAVFDEP
VIPA--APVPGAASDVGSSVWAAGA----LASEEKGWAKFTDFQPFCCSESG---PRCSS
PVDTNPSHAESGQCPSPEKTF--------GPASPCAWNVCVARKAPLVASDSSSSGGSDS
EDEEK------AAGTAETVSSGPSREAPSPPRKEA--------------------AAGRA
ECVS-CTPPDSAG--PVPSKVTSALA------------MAVSL---EATMATPVVSTAMA
EALPAGPIMEVTTIPA--------PVATLGTVTKDRETDAR-PEGAALNGPV

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MFWK
FDLNTTSHVDKLLDREDVTLRELMDEDDILQECKAQNQKLL-GFLCRQQCMEE---LVSL
ITQDPPLDMDEKVRFKYPNTACELLTCDVPQINDR-LGGDETLLNLLYDFLDHEPPLNPL
LASF--FSKTI

PF04499 // ENSGT00390000009899_2_Domain_0 (312, 565)

GNLIARKTEQVILFLKKKDRFLSLVLKHIGTSALMDLLLRLVSCVEPVG
LRQEVLHWLNEEKIIQRLVELIHPSQDEDRQSNASQTLCDIIRLGREQGSQLQEAP-EPD
PLLA-VLESQDCVEQLLKNMFDGDQTEICLVSGTQVLLTLLETRRAGT------------
------EG-LVDSFSQGLEGL-CTVSSSVLHGIEPRLKDFHQLLLSPPKKKAILTTIGVL
EEPLGNARLHGARLMAALLHTNTP

ENSGT00390000009899_2_Linker_0_6 (565, 566)

S

PF04499 // ENSGT00390000009899_2_Domain_6 (566, 744)

INQELCRLNTMGLLLDLFFKYTWNNFLHFQVELCI
AAILSHAAREDRAEASRPESGV--EPLPGSGD-----PETPQP-AASRLENTMVTHLFQK
CCLVQRILEAWEANDHAQAAGGMRRGNMGHLTRIANAVVQNLERGPMQTHISE--VIRGL
PADCRGRWENFVEETLAETNRRNAVDLVSTHHLHPSSEDEDMEGAFPNELSLQQ-AFSEY
QVQQMTATFVDQFGFNDEEFADQDDSVNAPFDRIAEINFSIDADE--DSPSAALFEACCS
DHIQPFDD-----------DEEDDIWEDKEMHCMARVTARARFGGPHTSESCSKNGLERG
GQDRKEGLEADKD-----------AARAGAPLGSTQKE-P-RLEGGS-EGTSWS-VFDEP
GNSP--APAPGVAVDVGSSVWAASTS-SPSALEEKGWAKFTDFQPFCCSESG---PRCSS
PVDTGHGDAPDGPDQGPERAR-AL---ASGPASPCAWSVCVTRKAPLVASDSS-------
-ED-------KTAGALEAVSMGPSREAPPLPTSAP-RCAEWG--------------VRRA
PGAHGRLQFEPAP--PAPAETPHAPAV--AAPPEATPA-------------ALASA---P
GMTAAGPPAAVTTVAPA-----TCTAAVLGTGTKDRKMDSPPPAGAALNGPV

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MFWK
FDLSTTSHIDKLLDKEGVTLRELMDEDDLLQECKAQNRRLL-DFLCQPWCMRE---LVGL
VTRDPPLDMEEKVRFXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---XXXXXXXXX
XXXXXXXXXXXXXXXXXXX

PF04499 // ENSGT00390000009899_2_Domain_0 (320, 745)

XXVIVFLKKKDGFVGLVLRHLGTSAMTDLLLRLVSCVEPAG
LRQEVLRXXXXXXXXXXXXXXXXXXXXXXRQSNASQTLCDIIRLGREQSGQLQEMA-EPD
PLLA-VLESQGCVEQLLRNMFDGDQTESCLVHGMQVLLTLLEARRAGT------------
------EGGSVDSFSQGLERP-HGVSSSVLQGIEPRLRDFHRLLLSPPKKSAILTTIGVL
EEPLGNARLHGARLVAALLRTNTPSVNQELCRLSTMDLLLDLFFKYTWNNFLHFQVELCI
AAILSHAAQEERDEVSESMSRS--EPAPQNGT-----SLDPQP-AAGCPEDTLVMHLFQK
CCLVQRILEAWEANDQTQADGGMRRGNMGHLTRXXXXXXXXXXXXXXXXXXXX--XXXXX
XXXXXXXXXXXXXETLT-EHRRNTVDLVSTHHLHSSSEDEDVDSAFPSGLSLQQ-AFSEYQIQQMTASFVDQFGFNDEEFVDQDDNINAPFDRVAEISFSTDADA--

PF04499 // ENSGT00390000009899_2_Domain_4 (320, 745)

XXVIVFLKKKDGFVGLVLRHLGTSAMTDLLLRLVSCVEPAGLRQEVLRXXXXXXXXXXXXXXXXXXXXXXRQSNASQTLCDIIRLGREQSGQLQEMA-EPDPLLA-VLESQGCVEQLLRNMFDGDQTESCLVHGMQVLLTLLEARRAGT------------------EGGSVDSFSQGLERP-HGVSSSVLQGIEPRLRDFHRLLLSPPKKSAILTTIGVLEEPLGNARLHGARLVAALLRTNTPSVNQELCRLSTMDLLLDLFFKYTWNNFLHFQVELCIAAILSHAAQEERDEVSESMSRS--EPAPQNGT-----SLDPQP-AAGCPEDTLVMHLFQKCCLVQRILEAWEANDQTQADGGMRRGNMGHLTRXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXETLT-EHRRNTVDLVSTHHLHSSSEDEDVDSAFPSGLSLQQ-AFSEY
QIQQMTASFVDQFGFNDEEFVDQDDNINAPFDRVAEISFSTDADA--DSXXXXXXXXXXX
XXXXXXXXXXXXX--------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XX--X
X-XXXXXXXXXX------------XXXXXXXXXXXXXXXXXXXXXXXXXXAGWAAVFDEP
VSAA--LQAPGAAVDVGSSVWAVSTP-GGCSPEEKGWAKFTDFQPFCCSDSG---PRCSS
PADTDGCDVQSGPNQGPEKSXXXXXXXQACPAPLSAWNTCAPRRAPLVAPGSSCPGASDR
EGMEQ-----SVGGALDPAGSAFSQESPLRTTEAVPRREG---------------GVGWT
DHS-PSTPLDPAS--PVTADPATSPAE--TMPSTAAETATVVLSRAGYPAVTLATSTALA
VMAPPGPIMLVTTAAPL--------------ETKDRKTEALPPAGATANGPV

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MFWK
FDLSAMSHVDKLLDKEGVTLRELMDGEDILQECKAQNRKLL-DFLCRRQSMEE---LVGL
VTQDPALDLEERARFKYPNTACELLTCDVPQINDR-LGGDETLLNVLYNFLDREPPLNPL
LASF--FSKTI

PF04499 // ENSGT00390000009899_2_Domain_0 (312, 564)

GNLIARKTEQVIAFLRKKDKFISLVLKHIGTSALMDLLLRLVSCVEPVG
LRQEVLHWLNEEKTIQRLVELIHPSQDEDRQSNASQTLCDIIRLGREQGSQLLEAP-QPD
PLLT-VLESQECVEQLLRNMFDGVQTELCLVSGTQVLLTLLEPRRAGS------------
-------EGLLDSCSQGLDRP-CTVSPGVLRGIEPRLKDFHQLLLSPPKKAAILTTVGVL
EEPLGNARLHSARLVAALLHTGT

ENSGT00390000009899_2_Linker_0_6 (564, 566)

PS

PF04499 // ENSGT00390000009899_2_Domain_6 (566, 744)

INQELCRLDTMGLLLDLFFKYTWNNFLHLQVELCI
AAILSHAAREDRAAASGPEDAL--EPPPSSGD-----PAAPQP-ASSLPEGTMVTHLFQK
CCLVQRILEAWEANDRTQAAGGMRRGNMGHLTRIANAVVQNLEGGPLQSQVSE--VFRGL
PADCRGRWESFVEETLSEANRRNAVDLVSTHHLHPSSEDEDMEGVLPSELSLQQ-AFSEY
QVQQMTATFVDQFGFSDEEFAEQDDSVNAPFDRIAEISFTVDADD--DSPGAALFEACCS
DHIQPFDE-------------DDDLWEAEETHRAARV-TRARFGGPHASERCPKDGPERR
GQGAGEGVGAV-------------------------QAGS-PCEGGSEAGSSWA-VFDGP
VTPMAASPAPAVARDVGSSVWAAGSP-STSAPEEKGWAKFADFQPFCCSESG---PRCSS
PVDTGHGDTQAGLNQGPERAHLEATGLSGGPACVGAWSTCVPRKAPLVAASSR-------
-EDEQ-----KAAAALEAVGVGPSQKASPL------------------------------
------------------------------------------------------------
----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MFWK
FDLSATSHVDKLLDKEGVTLRELMDGEDILQECKAQNRKLL-DFLCRRQSMEE---LVGL
VTQDPALDLEERARFKYPNTACELLTCDVPQINDR-LGGDETLLNVLYNFLDREPPLNPL
LASF--FSKTI

PF04499 // ENSGT00390000009899_2_Domain_0 (312, 566)

GNLIARKTEQVVAFLRKKDKFISLVLKHIGTSALMDLLLRLVSCVEPAG
LRQEVLHWLNEEKTIQRLVELIHPSQDEDRQSNASQTLCDIVRLGREQGSQLLEAP-QPD
PLLM-VLESQECVEQLLRNMFDGVQTELCLVSGTQVLLTLLEPRRAGS------------
-------EGLLDSCSQGLDRS-CTISPGVLHGIEPRLKDFHQLLLSPPKKAAILTSVGVL
EEPLGNARLHSARLVAALLHTGTPSINQERLRLSRVRPWVPVRTG---------GQA---
A--APDQARL-REAAQRHVLPL--GPAPVLAR-----T--------GLP-----------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------MQTSSAAVRMFWK
FDLNTTSHVDKLLDKEHVTLQELMDEDDILQECKAQNQKLL-DFLCRQQCMEE---LVSL
ITQDPPLDMEEKVRFKYPNTACELLTCDVPQISDR-LGGDESLLSLLYDFLDHEPPLNPL
LASF--FSKTI

PF04499 // ENSGT00390000009899_2_Domain_0 (312, 565)

GNLIARKTEQVITFLKKKDKFISLVLKHIGTSALMDLLLRLVSCVEPAG
LRQEVLHWLNEEKVIQRLVELIHPSQDEDRQSNASQTLCDIVRLGRDQGSQLQEAL-EPD
PLLT-ALESQDCVEQLLKNMFDGDRTESCLVSGTQVLLTLLETRRVGLKLLVVASWRCIC
QHVWNRTEGLVDSFSQGLERS-YTVSSSVLHGIEPRLKDFHQLLLNPPKKKAILTTIGVL
EEPLGNARLHGARLMAALLHTNTP

ENSGT00390000009899_2_Linker_0_6 (565, 566)

S

PF04499 // ENSGT00390000009899_2_Domain_6 (566, 744)

INQELCRLNTMDLLLDLFFKYTWNNFLHFQVELCV
AAILSHAAREDRTEASGSESRA--EPLHENG---NRSLETTQP-PASLPDNTMVTHLFQK
CCLVQRILEAWEANDHTQAAGGMRRGNMGHLTRIANAVVQNLERGPVQTHISE--VIRGL
PADCRGRWESFVEETLTETNRRNTVDLVSTHHLHSSSEDEDIEGAFPNELSLQQ-AFSDY
QIQQMAASFVDQFGFNDEEFADQDDNINAPFDRIAEINFNIDADE--DSPSAALFEACCS
DHIQPFDD-----------DEDEDIWEDSDTRCATRVMARARFGAPHASDSCSKNGPDRG
GQDGKASSEAHGD-----------APGAGAPPAPGKKEAP-TVEGDSE-GATWTAVFDEP
ANST--PTAPGVVRDVGSSVWAAGT----SAPEEKGWAKFTDFQPFCCSESG---PRCSS
PVDTERSRAEGSRSQGPEKA--------FSPASPCAWNVCVTRKAPLLASDSSSSGGSDS
-EDYQ-----KAASAVDAVSRSPGREAPPRPTVAR-TEEA----------------VGRA
ECA-DSRLLDPAC--PAPKEVTAAPAV--APPPEAAVAITTALSKAGPAIPTPAVSSAVA
VAVPLGPIMAVTTAPA--------MVATLGTVTKDGKRDAP-PEGAALNGPV

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MFWK
FDLNTTSHVDKLLDKEQVTLRELMDEDDILQECKAQNQKLL-DFLCRPQCMEE---LVGL
VTQDPPLDMDEKVRFKYPNTACELLTCDVPQISDR-LGEDGHLLGLLCSFLGREPPLNPL
LASF--FSKTI

PF04499 // ENSGT00390000009899_2_Domain_0 (312, 564)

GHLIARKTQQVITFLKKKDKFISLVLKHIGTSALMDLLLRLVSCVEPTG
LRQEVLQWLDEEKIIQRLVALIHPSQDEDKQSNASQTLCDIVRLGRDQGSDLPEAS-EPD
PLLT-VLESQNCVEQLLKNMFDGDQTESCLVSGTQVLLTLLETRRAGT------------
-------EGLVDTFSQGLERP-HVVSSSVLQGIEPRLKDFHQLLLNPPKKKAILTTIGVL
EEPLGNARLHGARLMAALLHTNT

ENSGT00390000009899_2_Linker_0_6 (564, 566)

PT

PF04499 // ENSGT00390000009899_2_Domain_6 (566, 744)

INQELCRLNTMDLLLDLFFKYTWNNFLHFQVELCI
AAILSHTSREDE----------------------NRNVETPQP-APGLPENTMVTHLFQK
CCLVQRILEAWEANDHTQAAGGMRRGNMGHLTRIANAVVQNLERGPVQTHIRE--VIRGL
PADCRGRWESFVEETLTETNRRNTVDLVSTHHLHSSSEDEDIEGAFPNELSLQQ-SFSEY
QIQQMTANFVDQFGFNDEEFADQDDNMNAPFDRIAEINFNIDADE--DSPSAALFEACCS
DRIQPFDDD----------EEEEDIWEDKETRCATQAVARARFGAPQASESCTKDGLEHR
GQDRKASSEADRD-----------ALGVGTPTAPVS---------------KWTAVFDES
VNST--PTTPGVVRDRGSSVWAAST----LAPEERGWAKFTDFQPFCCTESG---PRCSS
PVDTGCSHA------------------EVGPASPCAWNVCVTRKAPLVVSDSSSSGGSDS
EDEEK------AAGATESMGRGPGPEAPLLPKVAR-TEAAVI---------------SRS
-EG---------------------------------------------------------
----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MFWK
FDLNTTSHVDKLLDKEHVTLQELMDEDDILQECKAQNQKLL-DFLCRQQCMEE---LVNL
ITQDPPLDMEEK-------------------ISDR-LGEDESLLNLLYDFLDQEPPLNPL
LASF--FSKTI

PF04499 // ENSGT00390000009899_2_Domain_3 (312, 368)

GNLIARKTEQVIMFLKKKEKFISLMLKHIGTSALMDLLLRLVSCVEPVG
LRQEVLHVSTRDCV----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MFWK
FDLNTTSHIDKLLDKEHVTLQELMDEDDILQECKAQNQKLL-DFLCRQQCMEE---LVNL
ITQDPPLDMEEKVRFKYPNTACELLTCDVPQISDR-LGEDESLLNLLYDFLDQEPPLNPL
LASF--FSKTI

PF04499 // ENSGT00390000009899_2_Domain_0 (312, 569)

GNLIARKTEQVIMFLKKKEKFIGLMLKHVGTSALMDLLLRLVSCVEPVG
LRQEVLHWLNEEKIIQRLVELIHPHQDEDRQSNASQALCDIIRLGRDQGSQLQEAV-DPD
PLLL-TLESQDCVEQLLKNMFDGDQMESCLVSGMQVLLALLEPRRVGT------------
------EG-LVDSFSQGLERS-ESVNSSILHGIEPWLKNFHQLLLHPPKKKAILTTIGVL
EEPLGNARLHGARLMAALLHTNTPSINQ

ENSGT00390000009899_2_Linker_0_6 (569, 569)

PF04499 // ENSGT00390000009899_2_Domain_6 (569, 744)

ELCRLNTMDLLLDLFFKYTWNNFLHFQVELCI
AAILSHAAREEPAEASGSNGKV--EPLQGSGD-GTGKPETPQS-VTSLPENTMVTHLFQK
CCLVQRILEAWEANDHTQAAGGMRRGNMGHLTRIANAVVQNLEQGPVQTHISE--VIRGL
PADCRGRWESFVEETLMETNRRNTVDL----------------------------AFSEY
QIQQMTANFVDQFGFNDEEFADQDDNINAPFDRIAEINFNIEADE--DSPTAALFEACCS
DRIQPFDD-----------EEEEDIWEDEETRCTARVMARARFGAPHVSENYSKNSLEHG
GQDRKAGLAAARN-----------VPGLATPSSPTQKEGP-RSDSDLE-GTTWTAVFDEP
VNPM--SAAPGASRDVGSSVWAAGP----SAPEEKGWAKFTDFQPFCCSESG---PRCSS
PVDMDHSHAEGGQSPGPEKAF--------GPTSPCAWNVCVTRKAPLVASDSSSSGGSDS
EEDEK------AAGAVEAVCTGHGGKASPLP---K-TEEA---------------VASRA
ECT-DSTVLAPAC--PSSPEVIISSAV--ATT---------APSKAGPPTATIVVSSSVA
TTVPPGPIMAVTTAAPA-------LVATLG--TKDRKTDAL-PEGAALNGPV

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------YPNTACELLTCDVPQISDR-LGGDESLLSLLYDFLDHEPPLNPL
LASF--FSKTI

PF04499 // ENSGT00390000009899_2_Domain_0 (312, 569)

GNLIARKTEQVITFLKKKDKFISLVLKHIGTSALMDLLLRLVSCVEPAG
LRQEVLHWLKEEKVIQRLVELIHPSQDEDRQSNASQTLCDIVRLGRDQGSQLQEAL-EPD
PLLT-ALESQDCVEQLLKNMFDGDRTESCLVSGTQVLLTLLETRRVG-------------
------TEGLVDSFSQGLERS-YTVSSSVLHGIEPRLKDFHQLLLNPPKKKAILTTIGVL
EEPLGNARLHGARLMAALLHTNTPSINQ

ENSGT00390000009899_2_Linker_0_6 (569, 569)

PF04499 // ENSGT00390000009899_2_Domain_6 (569, 744)

ELCRLNTMDLLLDLFFKYTWNNFLHFQVELCI
AAILSHAAREDRTEASGSESRA--EPLHENG---NRSLETPQP-PTSLPDNTMVTHLFQK
CCLVQRILEAWEANDHTQAAGGMRRGNMGHLTRIANAVVQNLERGPVQTHISE--VIRGL
PADCRGRWESFVEETLTETNRRNAVDLVSTHHLHSSSEDEDIEGAFPNELSLQQ-AFSDY
QIQQMAASFVDQFGFNDEEFADQDDNINAPFDRIAEINFNIDADE--DSPSAALFEACCS
DRIQPFDD-----------DEDEDIWEDSDTRCATRVMARARFGAPHASESCSKNGPERG
GQDGKASSEAHGD-----------APGAGAPPAPGKKAAP-PVEGDSE-GAMWTAVFEEP
ANST--PTAPGVVRDVGSSVWAAGT----SAPEEKGWAKFTDFQPFCCSESG---PRCSS
PVDTERSRAEGSRSQGPEKAS-QASSFAVSPASPCAWNVCVTRKAPLLASDSSSSVGSDS
EDDYQ-----KAASAVDAVSRGPGREAPPLPTVAR-TEEA----------------VGRA
ECP-DSRLLDPAC--PAPKEVTAAPAV-------AAVAITTALSKAGPAIPTPAVSSAVA
VAVPLGPIMAVTTAPA--------MVATLGTVTKDRKTDAP-PEGAALNGPV

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MFWK
FDLNTTSHVDKLLDKEDVTLHELMDEDDILQECKAQNRKLL-DFLCQQHCMEE---LVNL
ITHEPPMDMDEKVRFKYPNTACELLTSDVPQINDK-LGGDETLLNILYDFLDHEPPLNPL
LASF--FSKT

PF04499 // ENSGT00390000009899_2_Domain_0 (311, 745)

IGNLIARKTEQVIAFLRKKDKFISLVLKHIDTSAMMDLLLRLISCVEPAT
LRQEVLNWLNEARIIQRLVELIHSSQDEDRQSNASQTLCDIIRLSRDQSNQLQDIP-EPD
PLLT-ALESQECVEQLLKNMFDGEQTENCIVNGTQVLLTLLETRRSGV------------
-------EGLMDSYTQGFERS-YTVNSSILHGIEPRLKDFHQLLLSPPKKTAILTTIGVL
EEPLGNARLHGSRLIAALLHTNTPSINQELCRLSTMDLLLTYFLNYTWNNFLSFPA----
--ILSHSVQEDIISSVSSGGNC--IYFSECILASNYKI-NT-RSMSYPLHKKQFSQLFQK
CCLVQRILDAWEANDKIQAEGGMRRGNMGHLTRIANAVVQNMEKGPMHTQISE--FIKEL
PEDCRGRWESFVEETLTETNRRNTVDL----------------------------AFSEYQIQQMTANFVDQFGFNDEEFADQDDNINAPFDRIAEIN

PF04499 // ENSGT00390000009899_2_Domain_4 (311, 745)

IGNLIARKTEQVIAFLRKKDKFISLVLKHIDTSAMMDLLLRLISCVEPATLRQEVLNWLNEARIIQRLVELIHSSQDEDRQSNASQTLCDIIRLSRDQSNQLQDIP-EPDPLLT-ALESQECVEQLLKNMFDGEQTENCIVNGTQVLLTLLETRRSGV-------------------EGLMDSYTQGFERS-YTVNSSILHGIEPRLKDFHQLLLSPPKKTAILTTIGVLEEPLGNARLHGSRLIAALLHTNTPSINQELCRLSTMDLLLTYFLNYTWNNFLSFPA------ILSHSVQEDIISSVSSGGNC--IYFSECILASNYKI-NT-RSMSYPLHKKQFSQLFQKCCLVQRILDAWEANDKIQAEGGMRRGNMGHLTRIANAVVQNMEKGPMHTQISE--FIKELPEDCRGRWESFVEETLTETNRRNTVDL----------------------------AFSEY
QIQQMTANFVDQFGFNDEEFADQDDNINAPFDRIAEINFNIDADD--DSPNASLFEACCN
ERIQQFDDN----------EEEEDIWEEKEITYATQVKSRTRFGASQASESSSKSDLENG
DHDGSVDSEEEEE--TEQQ-----VPSSSANSNKSNAAE--QKESDSSEGSGWTAVF-EP
VSSK--PPTPCVAMDVGSSVWDSAAP-ENAAP-EKGWAKFTDFQPFCCSESG---PRCSS
PADTESSDSDG-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MFWK
FDLNTTSHVDKLLDKEHVTLQELMDEDDILQECKAQNQKLL-GFLCRQQCMEE---LVNL
ITQDPPQDMEEKVRFKYPNTACELLTCDVPQISDR-LGEDESLLNLLYDFLDQEPPLNPL
LASF--FSKTI

PF04499 // ENSGT00390000009899_2_Domain_0 (312, 569)

GNLIARKTEQVIVFLKKKDKFISLILKHIGTSALMDLLLRLVSCVEPVG
LRQEVLHWLNEEKIIQRLVELIHPHQDEDRQSNASQALCDIIRLGRDQGSQLQETV-EPD
PLLI-ALESQDCVEQLLKNMFDGDQTESCLVSGMQVLLALLEPRRVGT------------
------EG-LVDSFSQGLERS-HSVSSSILRGIEPWLKNFHQLLLNPPKKKAILTTIGVL
EEPLGNARLHGARLMAALLHTNTPSINQ

ENSGT00390000009899_2_Linker_0_6 (569, 569)

PF04499 // ENSGT00390000009899_2_Domain_6 (569, 744)

ELCRLNTMDLLLDLFFKYTWNNFLHLQVELCI
AAILSHAAPEEQTEASGSDSKA--EPLQGSGD-GNGKLETAPS-ITSPPENTMVTHLFQK
CCLVQRILEAWEANDHTQAAGGMRRGNMGHLTRIANAVVQNLEQGPVQTHISD--IIRGL
PADCRGRWESFVEETLMETNRRNTVDL----------------------------AFSEY
QIQQMTANFVDQFGFNDEEFADQDDNINAPFDRIAEINFNIEADE--DSPSAALFEACCS
DRIQPFDD-----------DEEEDIWEDDETRCTARVMARARFGAPHVSDNYSKNALEHG
GQDRKTGSAVARN-----------VPGLAAPSSPTQKEGP-RSESDSA-GTTWTAVFDEP
VNPL--SATPGAARDVGSSAWAAGP----SVAEEKGWAKFTDFQPFCCSETG---PRCSS
PVDMDHSNAEGGQSPGPEKTF--------GPSSPCAWNVCVTRKAPLVASDSSSSGGSDS
EDDEK-----AAAGAVEAVCTGHTGKASPPL---R-TAEA---------------AVGRA
ECP-DSTVLAPAC--PAPSEVTISPAV--ATI---------APSKAGSPTATIVVSSSVA
AAVPPGPIMAVTTAAPA-------IVATMGTMTKDRKADAL-PEGAALNGPV

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MFWK
FDLNTTSHVDKLLDKEHVTLQELMDEDDILQECKAQNQKLL-DFLCRQQCMEE---LVSL
ITQDPPLDMEEKVRFKYPNTACELLTCDVPQISDR-LGGDESLLSLLYDFLGHEPPLNPL
LASF--FSKTI

PF04499 // ENSGT00390000009899_2_Domain_0 (312, 569)

GNLIARKTEQVITFLKKKDKFISLVLKHIGTSALMDLLLRLVSCVEPAG
LRQEVLHWLNEEKVIQRLVELIHPSEDEDRQSNAAQTLCDIVRLGRDQGSQLQEAL-EPD
PLLT-ALESQDCVEQLLKNMFDGDKTESCLVSGTQVLLTLLETRRVG-------------
------TEGLVDSFSQGLERS-YAVSSSVLHGIEPRLKDFHQLLLNPPKKKAILTTIGVL
EEPLGNARLHGARLMAALLHTNTPSINQ

ENSGT00390000009899_2_Linker_0_6 (569, 569)

PF04499 // ENSGT00390000009899_2_Domain_6 (569, 744)

ELCRLNTMDLLLDLFFKYTWNNFLHFQVELCI
AAILSHAAREERTEARGSDSRV--EPPHENE---NRSLETPRL-ATSPPDNTMVTHLFQK
CCLVQRILEAWEANDHTQAAGGMRRGNMGHLTRIANAVVQNLERGPVQTHISE--VIRGL
PADCRGRWESFVEETLTETNRRNTVDLVSTHHLHSSSEDEDIEGAFPNELSLQQ-AFSDY
QIQQMTANFVDQFGFNDEEFADQDDNINAPFDRIAEINFNIDADE--DSPSAALFEACCS
DRIQPFDD-----------DEDEDIWEDSDTRCATRVTARARFGAPHASESCSKNGLECR
SQDRKAS-SVDGD-----------VPGAHAPSAPGKNEAP-SVEGDSE-GATWTAVFDEP
ANST--PMAPGVVRDVGSSVWAAGT----SAPEEKGWAKFTDFQPFCCSESG---PRCSS
PVDTECSHAEGSRSQGPEKAS-QASCFAVSPASPCAWNVCATRKAPLLASDSSSSGGSDS
EDDDQ-----KAASATDAVSRGPGWEAPPLPTVTR-TEAA----------------VGRA
ECA-DSKLLDPAC--PVPKEVTAAPAV--AAPPEATVATTTALSKAGPAIATPAVSSAVA
VAAPLRPIMAVTTAPA--------MVDTLGTVTKDGKTDAP-PEGAALNGPM

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MFWK
FDLNTTSHVDKLLDKEDVTLRELMDEDDTLQECKAQNRKLL-DFLCRQQCMEE---LVSL
ITQDPPLDMEEKVRFKYPNTACELLTCDVPQINDR-LGGDETLLNLLYDFLDHEPPLNPL
LASF--FSKT

PF04499 // ENSGT00390000009899_2_Domain_0 (311, 745)

IGNLIARKTEQVIVFLKKKDKFVSLVLRHIGTSALMDLLLRLVSCVEPAG
LRQEVLHWLDEEKVIQRLVELIHPSQDEDXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXX
XXXX-XXXXQDCVEQLLRNMFDGDQTESCLVSGTQVLLTLLEGRRAGT------------
------EG-LVDSFSQGLERL-CPVSGSVLHGIEPRLKDFHQLLLSPPKKTAILTTIGVL
EEPLGNARLHGARLMAALLHTNTPSINRELCRLNTMGLLLDLFFKYTWNNFLHFQVELCI
GAILSHASREDGAEAGGPESMA--EPPPGNGH-----PETPQS-AASHPENTMVMHLFQQ
CCLVQRILEAWEANDHTQAAGGMRRGNMGHLTRIANAVVRNLEGGPAQTPVSE--VIRGL
PADCRGRWESFVEETLTETNRRNAVDLVSTHHLHPSSEDEDMEGVFPNELSLQX-XXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXAPFDRIAEIN

PF04499 // ENSGT00390000009899_2_Domain_4 (311, 745)

IGNLIARKTEQVIVFLKKKDKFVSLVLRHIGTSALMDLLLRLVSCVEPAGLRQEVLHWLDEEKVIQRLVELIHPSQDEDXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXX-XXXXQDCVEQLLRNMFDGDQTESCLVSGTQVLLTLLEGRRAGT------------------EG-LVDSFSQGLERL-CPVSGSVLHGIEPRLKDFHQLLLSPPKKTAILTTIGVLEEPLGNARLHGARLMAALLHTNTPSINRELCRLNTMGLLLDLFFKYTWNNFLHFQVELCIGAILSHASREDGAEAGGPESMA--EPPPGNGH-----PETPQS-AASHPENTMVMHLFQQCCLVQRILEAWEANDHTQAAGGMRRGNMGHLTRIANAVVRNLEGGPAQTPVSE--VIRGLPADCRGRWESFVEETLTETNRRNAVDLVSTHHLHPSSEDEDMEGVFPNELSLQX-XXXXX
XXXXXXXXXX-XXXXXXXXXXXXXXXXXAPFDRIAEINFNVDADE--DSPSAALFEACCG
DHIQPFDD-----------EEDDDIWEDKEAHCAARVTARARFGGPQASENGLVPGVRD-
------PGEADTA-----------AARAGTPPATTQKEGP-RMDYGSE-GPTWT-VFDDP
VTPP--APARGVAMDVGSSVWADSTP-STSALEEKGWAKFADFQPFCCSESG---PRCSS
PVDTGLGNTQGGLRQGPERAPLGPSA----VPAPC---ACVCVRPPLCSYEKD-------
----------DKAVTSEAVSTGPGQEVLLLPTSVP-RCTG-------------SLAVGRA
QRA-TSTPPDPAS--PAPAEATFALAV--AVPPEA---ASTALSKASPVPVSPAVSPVLA
VAI---------TLQPVMASPAITTVAILGTVTKDRKVDVPAPAGATSNGPV

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MFWK
FDLNTTSHVDKLLDKEHVTLQELMDEDDILQECKAQNQKLL-DFLCRQQCMEE---LVNL
ITQDPPQDMEEKVRFKYPNTACELLTCDVPQISDR-LGEDESLLNLLYDFLDQEPPLNPL
LASF--FSKTI

PF04499 // ENSGT00390000009899_2_Domain_0 (312, 569)

GNLIARKTEQVMMFLKKKERFITQILKHIGTSALMDLLLRLVSCVEPVG
LRQEVLHWLNEEKIIQRLVELIHPHQDEDRQSNASQALCDIIRLGRDQGSQLQETV-EPD
PLLI-TLESQDCVEQLLKNMFDGDQTESCLVSGMQVLLALLEPRRVGT------------
------EG-LVDSFSQGLERS-HSVSSSILRGIEPWLKNFHQLLLNPPKKKAILTTIGVL
EEPLGNARLHGARLMAALLHTNTPGINQ

ENSGT00390000009899_2_Linker_0_6 (569, 569)

PF04499 // ENSGT00390000009899_2_Domain_6 (569, 744)

ELCRLNTMDLLLDLFFKYTWNNFLHLQVELCI
AAILSHAAREEQAEASGSDGKA--EPLQGSGD-GNGKLETAPP-ITSPPENTMVTHLFQK
CCLVQRILEAWEANDHTQAAGGMRRGNMGHLTRIANAVVQNLEQGPVQTHISE--VIRGL
PADCRGRWESFVEETLMETNRRNTVDL----------------------------AFSEY
QIQQMTANFVDQFGFNDEEFADQDDNINAPFDRIAEINFNIEADE--DSPSAALFEACCS
DRIQPFDD-----------DEEEDIWEDDETRCTARVMARARFGAPHVSDNYSKNALEHG
GQDRKTGSAVARN-----------VPGLAAPSSPTQKEGP-RSESDSA-GTTWTAVFDEP
VNPL--SATPGAARDVGSSAWAAGP----SVAEEKGWAKFTDFQPFCCSETG---PRCSS
PVDMDHSNAEGGQSPGPEKPF--------GPTSPCAWNVCVTRKAPLVASDSSSSGGSDS
EDDEK------AAGTVEAVCTGHTGKVSPPP---R-TAEA---------------AIGRA
ECP-DSTVLAPAR--PAPSEVTISPAV--ATI---------APSKAGSPTATMVASSSVA
AAVPPGPIMAVTTAAPA-------IVATLGTMTKDRKADAL-PEGAALNGPV

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------LTSQELMNEDDICKSAKAQNQKLL-DFLCRQQCMEE---LVNL
ITQDPPQDMEEKVRFKYPNTACELLTCDVPQISDR-LGEDESLLNLLYDFLDQEPPLNPL
LASF--FSKTI

PF04499 // ENSGT00390000009899_2_Domain_0 (312, 569)

GNLIARKTEQVIMFLKKKDKFISLILKHIGTSALMDLLLRLVSCVEPVV
LRQEVLHWLNEEKVIQRLVELIHPHQDEDRQSNASQALCDIIRLGRDQGSQLQETV-EPD
PLLT-ALESQDCVEQLLKNMFDGDRTESCLVSGMQVLLALLEPRRVGT------------
------EG-LVDSFSQGLERS-YSVSSSILHGIEPWLKNFHQLLLNPPKKKAILTTIGVL
EEPLGNARLHGARLMAALLHTNTPSINQ

ENSGT00390000009899_2_Linker_0_6 (569, 569)

PF04499 // ENSGT00390000009899_2_Domain_6 (569, 744)

ELCRLNTMDLLLDLFFKYTWNNFLHLQVELCI
AAILSHAGREEQAEAGRSDGKV--EPVQGSGD-GGGKPETTPS-ITSPPENTMVTHLFQK
CCLVQRILEAWEANDNTQAAGGMRRGNMGHLTRIANAVVQNLEQGPVQTHISE--VIRGL
PAECRGRWESFVEETLMETNRRNTVDL----------------------------AFSEY
QIQQMTANFVDQFGFNDEEFADQDDNINAPFDRIAEINFNIEADE--DSPSAALFEACCS
DRIQPFDD-----------D-EEDIWEDEETRCTARVMARARFGAPHTSENYSKKAVGHG
GQGRKTGSPTARN-----------VPGLATPSSPTQKEGP-RSESDSA-GTTWTAVFDEP
VNPL--SAASGAARDVGSSAWAAGP----SVAEEKGWAKFTDFQPFCCSETG---PRCSS
PVDMDHSNAEGGQSPGPEKAF--------GPTSPCAWNVCVTRKAPLVASDSSSSGGSDS
EDDEK------AAGAVEALCAGHTGKASPPP---R-TAEA---------------AAGRA
ECP-DSTVLAPAC--PAPSEVTISPAV--ATI---------APSKAGSPTATIVVSSSVA
TAVPPGPIMAVTTTAPA-------IVATLGTMTKDRKTDAL-PDGAALNGPV

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MFWK
FDLNTTSHVDKLLDKEDVTLHELMDEDDILQECKAQNRKLL-DFLCQQHCMEE---LVNL
ITHEPPMDMDEKVRFKYPNTACELLTSDVPQINDK-LGGDETLLNILYDFLDHEPPLNPL
LASF--FSKTI

PF04499 // ENSGT00390000009899_2_Domain_0 (312, 569)

GNLIARKTEQVIAFLRKKDKFISLVLKHIDTSAMMDLLLRLISCVEPAT
LRQEVLNWLNEARIIQRLVELIHSSQDEDRQSNASQTLCDIIRLSRDQSNQLQDIP-EPD
PLLT-ALESQECVEQLLKNMFDGEQTENCIVNGTQVLLTLLETRRSGV------------
-------EGLMDSYTQGFERS-YTVNSSILHGIEPRLKDFHQLLLSPPKKTAILTTIGVL
EEPLGNARLHGSRLIAALLHTNTPSINQ

ENSGT00390000009899_2_Linker_0_6 (569, 569)

PF04499 // ENSGT00390000009899_2_Domain_6 (569, 744)

ELCRLSTMDLLLDLFFKYTWNNFLHFQVELSI
AAILSHSVQEGRTTANDSESR-------EEVLNGNVTTENQ-ETPENNTENIMVTHLFQK
CCLVQRILDAWEANDKIQAEGGMRRGNMGHLTRIANAVVQNMEKGPMHTQITE--FIKEL
PEDCRGRWESFVEETLTETNRRNTVDLVSTHHLHSSSEDEDIESAFPNELSLQQ-AFSEY
QIQQMTANFVDQFGFNDEEFADQDDNINAPFDRIAEINFNIDADD--DSPNASLFEACCN
ERIQQFDDN----------EEEEDIWEEKEITYATQVKSRTRFGASQASESSSKSDLENG
DHDGSVDSEEEEE--TEQQ-----VPSSSANSNKSNAAE--QKEPDSSEGSGWTAVF-EP
VSSK--PPTPCVAMDVGSSVWDSAAP-ENAAP-EKGWAKFTDFQPFCCSESG---PRCSS
PADTESSDSDGNPKQSQDKNF-------S-TASPCVWNVCVTRKAPLVASDSSSSGGSDS
EDED-----EKGDVVTETISTGAGQETVKLTMDAK-NEKAVFTSDA-GCMVIDKLTITDM
GTTKASKPLNNAA---QHPEE---------------------------------------
----------------HQNTA-----PVTETATKDRKEEALPCAEATLNGPA

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MFWK
FDLNTTSHVDKLLDKEDVTLHELMDEDDILQECKAQNRKLL-DFLCQQECMEE---LVSL
ITHDPPLDMEEKVRFKYPNTACELLTSDVPQINDK-LGGDETLLNILYDFLDHEPPLNPL
LASF--FSKTI

PF04499 // ENSGT00390000009899_2_Domain_0 (312, 565)

GNLIARKTEQVITFLKKKDQFISLVLKHIDTSAMMDLLLRLISCVEPTT
LRQEVLNWLNEENIIERLVELIHSNQDEDRQSNASQTLCDIIRLSRDQSNQMQELS-EPD
PLLA-ALESQGCVEQLLKNMFDGDLTENCLVNGTQILLTLLETRRSGV------------
-------EGLMDSFSQGLERS-YTVNSSILHGIEPWLKDFHQLLLNPPKKMSILTTIGVL
EEPLGNARLHGARLIAALLHTNTP

ENSGT00390000009899_2_Linker_0_6 (565, 566)

S

PF04499 // ENSGT00390000009899_2_Domain_6 (566, 744)

INRELCRLNTMNLLLDLFFKFTWNNFLHFQVELCI
AAILSHSGREGGSSTSDSDCR-------EDINSGNENLEKT-ESTEIICENVMVTHLFQK
CHLVQRILDAWEANDRIQAEGGMRRGNMGHLTRIANAVVQNMEKGPIRSQICS--FIKEL
PEDCRGRWESFVEETLPETNRKNTVDLVSTHHLHSSSEDEDMESAFPNELSLQQ-AFSEY
QIQQMTANFVDQFGFNDEEFADQDDNINAPFDRIAEINFTIDADD--DSPNASLFEACCN
DRIQPFDDN----------EDEEDIWEDKEINYATQAKSRTRFGASHTSEYSRKSNLENG
DQEGSEDSEEEEG--AGEARHGAGIPLSGSSSTTNLTLQ--AEDLAASEGSGWTAVFDEP
VNSK--PPPSGVAMDIGSRVWDAAAP-DTATSEEKGWAKFTDFQSFCCSESG---PRCSS
PVDTGSSTSEGKPKPSQDKSF-------G-PAAPCVWNVCVARKAPLVASDSSSSGGSDS
EEEDEEEEEKKAGIIIETVGPGSGQEGLKLTMDAK-KEKAVSSSDA-EPLLIHKLPAAEK
GAPSASQPTPEPR---SPAAV---------------------------------------
----------------SPASAASASLPVVATS------VVLT---ATVSAVA

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MFWK
FDLNTTSHVDKLLDKEHVTLQELMDEDDILQECKAQNQKLL-DFLCRQQCMEE---LVSL
ITQDPPLDMEEKVRFKYPNTACELLTCDVPQISDR-LGGDESLMNLLYDFLDQEPPLNPL
LASF--FSKTI

PF04499 // ENSGT00390000009899_2_Domain_0 (312, 569)

GNLIARKTEQVIIFLKKKDKFISLVLKHMGTSALMDLLLRLVSCVEPTG
LRQEVLHWLNEEKIIQRLVELIHPNQDEDRQSNASQALCDIVRLGRDQGSQLQETV-EPD
PLLT-ALESQDCVEQLLKNMFDKDQTESCLVSGTQVLLALLEPRRAGT------------
------EG-LVDSFPQGLERS-YVVSSSVLHGIEPWLKDFHQLLLNPPKKEAILTTIGVL
EEPLGNARLHGARLMAALLHTNTPSINQ

ENSGT00390000009899_2_Linker_0_6 (569, 569)

PF04499 // ENSGT00390000009899_2_Domain_6 (569, 744)

ELCRLNTMDLLLDLFFKYTWNNFLHLQVELCV
AAILSHAAGEEQAEASGAESRV--EPPQGSANNRDGRLETPEP-TASLPENTMVTHLFQK
CCLVQRILEAWEANDHTQAAGGMRRGNMGHLTRIANAVVQNLERGPVQTHIRE--VIRGL
PADCRGRWENFVEETLTETNRRNTVDL----------------------------AFSEY
QIQQMTANFVDQFGFNDEEFADQDDNINAPFDRIAEINFNIDADE--DSPSAALFEACCS
DRIQPFDD-----------EEEEDIWEDEETRCTARGVARARFGGPHAPENDSR-----N
GQDKKASSEAARN-----------APGVGTPLASVQSEGP-VSE---A-GAAWTAVFDEL
ANAT--PTTPAAARDVGSSVWAASP----SAPEEKGWAKFSDFQPFCCSESG---PRCSS
PVDMDSSHTEGSQSAGPGKAF--------GPTSPCAWSVCVTRKAPLVASDSSSSGGSDS
EEDEK------VAGSVDAVNTSHGLEVPKLP---R-KEEA---------------TIGRA
KCA-DSMPPEPAR--PAPAQVTAAPAM--TVP----------------PEGTVAATMLSK
TGPPKAVSSALAATAPA-------GPASVGTVTKDRKTDDP-PEGAALNGPV

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MFWK
FDLNTTSHVDKLLDKEHVTLQELMDEDDILQECKAQNQKLL-DFLCRQQCMEE---LVSL
ITQDPPLDMEEKVRFKYPNTACELLTCDVPQISDR-LGGDESLLSLLYDFLDHEPPLNPL
LASF--FSKTI

PF04499 // ENSGT00390000009899_2_Domain_0 (312, 569)

GSLIARKTEQVITFLKKKDKFISLVLKHIGTSALMDLLLRLVSCVEPAG
LRQEVLHWLNEEKVIQRLVELIHPSQDEDRQSNASQTLCDIVRLGRDQGSQLQEAL-EPD
PLLT-ALESQDCVEQLLKNMFDGDRTESCLVSGTQVLLTLLETRRVG-------------
------TEGLVDSFSQGLERS-YTVSSSVLHGIEPRLKDFHQLLLNPPKKKAILTTIGVL
EEPLGNARLHGARLMAALLHTNTPSINQ

ENSGT00390000009899_2_Linker_0_6 (569, 569)

PF04499 // ENSGT00390000009899_2_Domain_6 (569, 744)

ELCRLNTMDLLLDLFFKYTWNNFLHFQVELCI
AAILSHAAREDRTEASGSESRA--EPLHENG---NRSLETPQP-PASLPDNTMVTHLFQK
CCLVQRILEAWEANDHTQAAGGMRRGNMGHLTRIANAVVQNLERGPVQTHISE--VIRGL
PADCRGRWESFVEETLTETNRRNTVDLVSTHHLHSSSEDEDIEGAFPNELSLQQ-AFSDY
QIQQMAASFVDQFGFNDEEFADQDDNINAPFDRIAEINFNIDADE--DSPSAALFEACCS
DRIQPFDD-----------DEDEDIWEDSDTRCATRVTARARFGAPHASDSCSKNGPERG
GQDGKASSEAHGD-----------APGAGAPLAPGKKEAP-TVEGDSE-GAMWTAVFDEP
ANST--PTAPGVVRDVGSSVWAAGT----SAPEEKGWAKFTDFQPFCCSESG---PRCSS
PVDTERSRAEGSRSQGPEKA--------FSPASPCAWNVCVTRKAPLLASDSSSSGGSDS
-EDYQ-----KAASAVDAVSRSSGREAPPRPTGAR-T-EA----------------VGRA
ECA-NSRLLDPAC--PAPKEVTAAPAV--APPPEAAVAITTALSKAGPAIPSPPVSSAVA
VAVPLGPIMAVTTAPA--------MVATLGTVTKDGKREAP-PEGAALNGPV

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MFWK
FDLNTTSHVDKLLDKEDVTLQELMEEDDLLQECKAQNRRLL-DFICQQQCMEQ---LVEL
ITQKPPDDMEEKVRFKFPNTACELLTCDVPQINDK-LGEDDNLLNILYDFLRQEPPLNPL
LASF--FSKT

PF04499 // ENSGT00390000009899_2_Domain_0 (311, 745)

IGNLIARKTEQVIGFLRKKEKFLALVLEHIGTSAMMDLLLRLISCVEPAP
LRQEVLHWLNEERLIQRLINLIHHSQDEDKQSNASQTLCDLIRLSRDQCNQMQETM-ETD
PLLA-TLESQPCVEQLLKNMFDGEQTESCIVSGTQILLTLLETRRQSV------------
-------DPLLNSLTQGYDRT-PTVSNCILQVIEPRLKDFHDLLQHPPKKESILTTIGVL
EEPLGNARLHTTRLIAALLHTNTPSINQELCRLGTMDLLLDLFFRYTWNNFMHLQVELCI
AAVLSNSRQEGKYLAVSEERQEEEETLNGNAE----NMENCQ-ICSSEHEDLMITHLFQK
CCLVQRILDAWETNDRIQAEGGMRRGNMGHLTRIANTVVQNMEKGPMQAQISD--FITEL
PDDCRGRWESFVEETLTETNRRNTVDLIVCMHLFTEKENVEIFIEMILLIFFTQ-AFSDYQIQQMTANFVDQFGFNDEEFAEQDDHINAPFDRITEIN

PF04499 // ENSGT00390000009899_2_Domain_4 (311, 745)

IGNLIARKTEQVIGFLRKKEKFLALVLEHIGTSAMMDLLLRLISCVEPAPLRQEVLHWLNEERLIQRLINLIHHSQDEDKQSNASQTLCDLIRLSRDQCNQMQETM-ETDPLLA-TLESQPCVEQLLKNMFDGEQTESCIVSGTQILLTLLETRRQSV-------------------DPLLNSLTQGYDRT-PTVSNCILQVIEPRLKDFHDLLQHPPKKESILTTIGVLEEPLGNARLHTTRLIAALLHTNTPSINQELCRLGTMDLLLDLFFRYTWNNFMHLQVELCIAAVLSNSRQEGKYLAVSEERQEEEETLNGNAE----NMENCQ-ICSSEHEDLMITHLFQKCCLVQRILDAWETNDRIQAEGGMRRGNMGHLTRIANTVVQNMEKGPMQAQISD--FITELPDDCRGRWESFVEETLTETNRRNTVDLIVCMHLFTEKENVEIFIEMILLIFFTQ-AFSDY
QIQQMTANFVDQFGFNDEEFAEQDDHINAPFDRITEINFNIEAED--DNPNAALFEACCN
ERIQQFDDE------------EEDIWEEKEIGYGTQVKSRTRFGVSQCSEDSSRSDLENG
EPTGSPVSDEDEDEEGH-SIETPQAANLITCSQSMQRDSVVPEGAVSPYKTGWTAVFDEP
VNSK--PPAPCVALDVGSNVWEAPIT-ETSTSEQKGWAKFPDFQPFCCSESG---PRCSS
PVDTESSSSDGRTKHSQDKLF--------SAASPCVWNVCVARKNPTLGSDSSSSGGSDS
DEEDK------HNIVTETISTGSGHETIRLTMDTK-NEKATFSS-NPDDVTIDQISVTDS
RPK-KASPLSSCT--EDPSQEQSAAAQC----------DTST------------------
----------------------------QS-TCKEKK---------------

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MFWK
FDLNTTSHVDKLLDKEHVTLQELMDEDDILQECKAQNQKLL-DFLCRQQCMEE---LVSL
ITQDPPLDMEEKVRFKYPNTACELLTCDVPQISDR-LGGDESLLSLLYDFLDHEPPLNPL
LASF--FSKTI

PF04499 // ENSGT00390000009899_2_Domain_0 (312, 569)

GNLIARKTEQVITFLKKKDKFISLVLKHIGTSALMDLLLRLVSCVEPAG
LRQDVLHWLNEEKVIQRLVELIHPSQDEDRQSNASQTLCDIVRLGRDQGSQLQEAL-EPD
PLLT-ALESQDCVEQLLKNMFDGDRTESCLVSGTQVLLTLLETRRVG-------------
------TEGLVDSFSQGLERS-YAVSSSVLHGIEPRLKDFHQLLLNPPKKKAILTTIGVL
EEPLGNARLHGARLMAALLHTNTPSINQ

ENSGT00390000009899_2_Linker_0_6 (569, 569)

PF04499 // ENSGT00390000009899_2_Domain_6 (569, 744)

ELCRLNTMDLLLDLFFKYTWNNFLHFQVELCI
AAILSHAAREERTEASGSESRV--EPPHENG---NRSLETPQP-AASLPDNTMVTHLFQK
CCLVQRILEAWEANDHTQAAGGMRRGNMGHLTRIANAVVQNLERGPVQTHISE--VIRGL
PADCRGRWESFVEETLTETNRRNTVDLVSTHHLHSSSEDEDIEGAFPNELSLQQ-AFSDY
QIQQMTANFVDQFGFNDEEFADQDDNINAPFDRIAEINFNIDADE--DSPSAALFEACCS
DRIQPFDD-----------DEDEDIWEDSGTRCAARVTARPRFGAPHASESCSKNGPERG
GQDGKASLEAHRD-----------APGAGAPPAPGKKEAP-PVEGDSE-GAMWTAVFDEP
ANST--PTAPGVVRDVGSSVWAAGT----SAPEEKGWAKFTDFQPFCCSESG---PRCSS
PVDTERSHAEGSRSQGPEKAS-QASYFAVSPASPCAWNVCVTRKAPLLASDSSSSGGSHS
EDGDQ-----KAASAMDAVSRGPGREAPPLPTVAR-TEEA----------------VGRV
GCA-DSRLLSPAC--PAPKEVTAAPAV--AVPPEATVAITTALSKAGPAIPTPAVSSALA
VAVPLGPIMAVTAAPA--------MVATLGTVTKDGKTDAP-PEGAALNGPV

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MFWK
FDLNTTSHVDKLLDKEHVTLQELMDEDDILQECKAQNQKLL-DFLCRQQCMEE---LVSL
ITQDPPLDMEEKVRFKYPNTACELLTCDVPQISDR-LGGDESLLSLLYDFLDHEPPLNPL
LASF--FSKTI

PF04499 // ENSGT00390000009899_2_Domain_0 (312, 569)

GNLIARKTEQVITFLKKKDKFISLVLKHIGTSALMDLLLRLVSCVEPAG
LRQDVLHWLNEEKVIQRLVELIHPSQDEDRQSNASQTLCDIVRLGRDQGSQLQEAL-EPD
PLLT-ALESQDCVEQLLKNMFDGDRTESCLVSGTQVLLTLLETRRVG-------------
------TEGLVDSFSQGLERS-YAVSSSVLHGIEPRLKDFHQLLLNPPKKKAILTTIGVL
EEPLGNARLHGARLMAALLHTNTPSINQ

ENSGT00390000009899_2_Linker_0_6 (569, 569)

PF04499 // ENSGT00390000009899_2_Domain_6 (569, 744)

ELCRLNTMDLLLDLFFKYTWNNFLHFQVELCI
AAILSHAAREERTEASGSESRV--EPPHENG---NRSLETPQP-AASLPDNTMVTHLFQK
CCLVQRILEAWEANDHTQAAGGMRRGNMGHLTRIANAVVQNLERGPVQTHISE--VIRGL
PADCRGRWESFVEETLTETNRRNTVDLVSTHHLHSSSEDEDIEGAFPNELSLQQ-AFSDY
QIQQMTANFVDQFGFNDEEFADQDDNINAPFDRIAEINFNIDADE--DSPSAALFEACCS
DRIQPFDD-----------DEDEDIWEDSGTRCAARVTARPRFGAPHASESCSKNGPERG
GQDGKASLEAHRD-----------APGAGAPPAPGKKEAP-PVEGDSE-GAMWTAVFDEP
ANST--PTAPGVVRDVGSSVWAAGT----SAPEEKGWAKFTDFQPFCCSESG---PRCSS
PVDTERSHAEGSRSQGPEKAS-QASYFAVSPASPCAWNVCVTRKASLLASDSSSSGGSHS
EDGDQ-----KAASAMDAVSRGPGREAPPLPTVAR-TEEA----------------VGRV
GCA-DSRLLSPAC--PAPKEVTAAPAV--AVPPEATVAITTALSKAGPAIPTPAVSSALA
VAVPLGPIMAVTAAPA--------MVATLGTVTKDGKTDAP-PEGAALNGPV

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MFWK
FDLNTTSHVDKLLDKEDVTLQELMDEDDLLQECKAQNRKLL-DFLCRQQCMEE---LVSL
ITQDPPLDMEEKVRFKYPNTACELLTSDVPQINDK-LGGDETLLNLLYDFLDHEPPLNPL
LASF--FSKT

PF04499 // ENSGT00390000009899_2_Domain_0 (311, 745)

IGNLIARKTEQVIVFLKKKDGFIGLVLRHLGTSAMMDLLLRLVSCVEPAG
LRQEVLHWLNEEKIIERLVGLIHPSQEEDRQSNASQTLCDIVRLGRDQGGQLQETA-EPD
PLLA-VLESQGCIEQLLRNMFDGEQTESCLVCGTQVLLTLLETRRAGT------------
------EGGSVDSFSQGLERL-HSVSSSVLQGIEPRLRDFHRLLLSPPKKSAILTTIGVL
EEPLGNARLHGARLVAALLHTNTPSINQELCRLNTMDLLLDLFFKYTWNNFLHFQVELCI
AAILSHATREERAEGGESVSRV--EPAPGNRT-----PKDPQP-AASHPEDTLVTHLFQK
CCLVQRILEAWEAKGHTQAAGGMRRGNMGHLTRIANTVVQNLEQGPMQTHISE--VIRGL
PEDCRGRWESFVEETLTETNRRNTVDL----------------------------AFSEYQIQQMTASFVDQFGFNDEEFADQDDNINAPFDRVAEIS

PF04499 // ENSGT00390000009899_2_Domain_4 (311, 745)

IGNLIARKTEQVIVFLKKKDGFIGLVLRHLGTSAMMDLLLRLVSCVEPAGLRQEVLHWLNEEKIIERLVGLIHPSQEEDRQSNASQTLCDIVRLGRDQGGQLQETA-EPDPLLA-VLESQGCIEQLLRNMFDGEQTESCLVCGTQVLLTLLETRRAGT------------------EGGSVDSFSQGLERL-HSVSSSVLQGIEPRLRDFHRLLLSPPKKSAILTTIGVLEEPLGNARLHGARLVAALLHTNTPSINQELCRLNTMDLLLDLFFKYTWNNFLHFQVELCIAAILSHATREERAEGGESVSRV--EPAPGNRT-----PKDPQP-AASHPEDTLVTHLFQKCCLVQRILEAWEAKGHTQAAGGMRRGNMGHLTRIANTVVQNLEQGPMQTHISE--VIRGLPEDCRGRWESFVEETLTETNRRNTVDL----------------------------AFSEY
QIQQMTASFVDQFGFNDEEFADQDDNINAPFDRVAEISFSTDADD--DSPHAALFEATAS
SPS-TF-D-----------DEEEDVWEDGELSRAARVTARARFGAPLAAESGSKSSLEHG
SRNGSVDTDAPRG-----ATPPAEGSRSPGPPAPVQKEGR-GGEGSAE-GAGWAAVFAEP
VSAA--LQAPGVAVDVGSSVWAVSTP-GAPMPEEKGWAKFTDLQPFCCSDSG---PRCSS
PVDTDSGNIQGGPNQCPEKTS--------CPAPPSAWNTCAPRKAPPVASSSRYTGALDR
EDVEQ-----GAGGIREGVFSQ---ETPP-----R-ATE----------------AIPRS
MPL-DSAPWGPTYNSPATADVATIPAE--ATPPAA------------AEVAALATSTALA
LVAPSGPIVAVTTVAPL--------------ETKNRKTEAPPPAGATANGPV

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MFWK
FDLNTTSHVDKLLDKAHVTLQELMDEDDILQECKAQNQKLL-DFLCRKQCMEE---LVSL
ITQDPPLDMEEKVRFKYPNAACELLTCDVPQISDC-LGGDESLLSLLYDFLGHEPPLNPL
LARP--VFS--------------ARPL

PF04499 // ENSGT00390000009899_2_Domain_0 (328, 569)

KKDKFISLVLKHIGTSALMDLLLHLVCCVEPAG
LQQEVLHWLNEEKVIQRLVELIHPSEDEDRQ------------LGRDQGSQLQEAL-ELD
PLLT-ALESQDCVEQLLKNMFDGDRTESCLVSGTQVLLTLLETRRVGT------------
-------EGLVDSFSQGLERS-YAVSSSVLHGIEPRLKDFHQVLLNLPKKKAILPTIGVL
EEPLRNARLHGPRLMAALLHTNTPSINQ

ENSGT00390000009899_2_Linker_0_6 (569, 569)

PF04499 // ENSGT00390000009899_2_Domain_6 (569, 744)

ELCRLNTMDLLLDLFFKYTWNNVLHFQVELCI
AAILSHAAREERTEARGSDSRV----------------------ESPPPDNMMVTHLFQK
CCLVQRILEAWEANDHAQAAGGMRRGNMGHLTRIANTVVQNLERSPVQTYISE--VIRGL
HADCRGRWESFVEETLMETNRRNTVDLVSTHHLHSSSEDEDIEGAFSNELSLQQ-AFSDY
QIQQMTANFVDQFGFNDEEFADQDDNINAPFDRIAEINFNIDADE--DSPRAALFE----
---------------------DEDIWEDSDTRCATWVTARARFGAPHASESCSKNSLECR
SQDRKASSVDGD------------VPGAHAPSAPGKNEAP-PVEGDSE-GATWTAVFDEP
ANST--P-MGCGFLCVG--SWYL-------SSRGEGWAKFTDFQPFCCSESG---PRCSS
PVDTECSHAEGSRSQGSEKAF--------SPASPCAWNVCATRKAPLS-----SSGGSDS
EDDDQ-----KAASATDAVSRGPSWEAPPLPTVTR-TEAA----------------VSRA
ECA-DSKLLDPAC--PMPKEVTSAPAV--AAPPEATVATTTALSKAGPAIATPAVSSAVA
VAAPLRPIMAVKTAPA--------MVDTLGTVTKDGKTNAS-PEGAALNGPM

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MFWK
FDLNTTSHVDKLLDKEHVTLQELMDEDDILQECKAQNQKLL-DFLCRQQCMEE---LVNL
ITQDPPQDMEEKVRFKYPNTACELLTCDVPQISDR-LGEDESLLNLLYDFLDQEPPLNPL
LASF--FSKTI

PF04499 // ENSGT00390000009899_2_Domain_0 (312, 569)

GNLIARKTEQVIMFLKKKEKFISQLLKHIGTSALMDLLLRLVSCVEPVG
LRQEVLHWLNEEKIIQRIVALIHPHQDEDRQSNASQALCDIIRLGRDQGSQLQETV-EPD
PLLI-TLESQDCVEQLLKNMFDGDQTESCLVSGMQVLLALLEPRRVGT------------
------EG-LVDSFSQGLERS-HSVSSSILRGIEPWLKNFHQLLLNPPKKKAILTTIGVL
EEPLGNARLHGARLMAALLHTNTPGINQ

ENSGT00390000009899_2_Linker_0_6 (569, 569)

PF04499 // ENSGT00390000009899_2_Domain_6 (569, 744)

ELCRLNTMDLLLDLFFKYTWNNFLHLQVELCI
AAILSHAAREEQAEASGSDGKV--EPLQGSGD-GNGKLETTPS-ITSPPENTMVTHLFQK
CCLVQRILEAWEANDHTQAAGGMRRGNMGHLTRIANAVVQNLEQGPVQAHISE--VIRGL
PADCRGRWESFVEETLMETNRRNTVDL----------------------------AFSEY
QIQQMTANFVDQFGFNDEEFADQDDNINAPFDRIAEINFNIEADE--DSPSAALFEACCS
DRIQPFDD-----------DEEEDIWEDDETRCAARVMARARFGAPHVSDNYSKNALEHG
GQDRKTGSAVARN-----------VPGLAAPSSPTQKEGP-RSESDSA-GTTWTAVFDEP
VNPL--SATPGAARDVGSSAWAAGP----SVVEEKGWAKFTDFQPFCCSETG---PRCSS
PVDMDHSNAEGGQSPGPEKTF--------GPTSPCAWNVCVTRKAPLVASDSSSSGGSDS
EDDEK------AAGAVEAVCTGHTGKVSPPP---R-TAEA---------------AVGRA
ECP-DSTVLAPAC--PAPSEVTISPAV--ATI---------APSKAGSPTATIVVSSSVA
AAVPPGPIVAVTTAAPA-------IVATLGTMTKDRKADAL-PEGAALNGPV

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MFWK
FDLNTTSHVDKLLDKEHVTLQELMDEDDILQECKAQNQKLL-DFLCRQQCMEE---LVSL
ITQDPPLDMEEKVRFKYPNTACELLTCDVPQISDR-LGGDESLLSLLYDFLDHEPPLNPL
LASF--FSKTI

PF04499 // ENSGT00390000009899_2_Domain_0 (312, 569)

GNLIARKTEQVITFLKKKDKFISLVLKHIGTSALMDLLLRLVSCVEPAG
LRQDVLHWLNEEKVIQRLVELIHPSQDEDRQSNASQTLCDIVRLGRDQGSQLQEAL-EPD
PLLT-ALESQDCVEQLLKNMFDGDRTESCLVSGTQVLLTLLETRRVG-------------
------TEGLVDSFSQGLERS-YAVSSSVLHGIEPRLKDFHQLLLNPPKKKAILTTIGVL
EEPLGNARLHGARLMAALLHTNTPSINQ

ENSGT00390000009899_2_Linker_0_6 (569, 569)

PF04499 // ENSGT00390000009899_2_Domain_6 (569, 744)

ELCRLNTMDLLLDLFFKYTWNNFLHFQVELCI
AAILSHAAREERTEASGSESRV--EPPHENG---NRSLETPQP-AASLPDNTMVTHLFQK
CCLVQRILEAWEANDHTQAAGGMRRGNMGHLTRIANAVVQNLERGPVQTHISE--VIRGL
PADCRGRWESFVEETLTETNRRNTVDLVSTHHLHSSSEDEDIEGAFPNELSLQQ-AFSDY
QIQQMTANFVDQFGFNDEEFADQDDNINAPFDRIAEINFNIDADE--DSPSAALFEACCS
DRIQPFDD-----------NEDEDIWEDSDTRCAARVTARPRFGAPHASESCSKNGPERG
GQDGKASLEAHRD-----------APGAGAPPAPGKKEAP-AVEGDSE-GAMWTAVFDEP
ANST--PTAPGVVRDVGSSVWAAGT----SAPEEKGWAKFTDFQPFCCSESG---PRCSS
PVDTEHSHAEGSRSQGPEKA--------FSPASPCAWNVCVTRKAPLLASDSSSSGGSHS
EDGDQ-----KAASAMDAVSRGPGREAPRLPTVAR-TEEA----------------VGRV
GCA-DSRLLSPAC--PAPKEVTAAPAV--AVPPEATVAITTALSKAGPAIPTPAVSSALA
VAVPLGPIMAVTAAPA--------MVATLGTVTKDGKTDAP-PEGAALNGPV

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MFWK
FDLNTTSHVDKLLDKEHVTLQELMDEDDILQECKAQNQKLL-DFLCRQQCMEE---LVSL
ITQDPPLDMEEKVRFKYPNTACELLTCDVPQISDR-LGGDESLLSLLYDFLDHEPPLNPL
LASF--FSKTI

PF04499 // ENSGT00390000009899_2_Domain_0 (312, 569)

GNLIARKTEQVITFLKKKDKFISLVLKHIGTSALMDLLLRLVSCVEPAG
LRQDVLHWLNEEKVIQRLVELIHPSQDEDRQSNASQTLCDIVRLGRDQGSQLQEAL-EPD
PLLT-ALESQDCVEQLLKNMFDGDRTESCLVSGTQVLLTLLETRRVG-------------
------TEGLVDSFSQGLERS-YAVSSSVLHGIEPRLKDFHQLLLNPPKKKAILTTIGVL
EEPLGNARLHGARLMAALLHTNTPSINQ

ENSGT00390000009899_2_Linker_0_6 (569, 569)

PF04499 // ENSGT00390000009899_2_Domain_6 (569, 744)

ELCRLNTMDLLLDLFFKYTWNNFLHFQVELCI
AAILSHAAREERTEASGSESRV--EPPHENG---NRSLETPQP-AASLPDNTMVTHLFQK
CCLVQRILEAWEANDHTQAAGGMRRGNMGHLTRIANAVVQNLERGPVQTHISE--VIRGL
PADCRGRWESFVEETLTETNRRNTVDLVSTHHLHSSSEDEDIEGAFPNELSLQQ-AFSDY
QIQQMTANFVDQFGFNDEEFADQDDNINAPFDRIAEINFNIDADE--DSPSAALFEACCS
DRIQPFDD-----------DEDEDIWEDSDTRCAARVMARPRFGAPHASESCSKNGPERG
GQDGKASLEAHRD-----------APGAGAPPAPGKKEAP-PVEGDSE-GAMWTAVFDEP
ANST--PTAPGVVRDVGSSVWAAGT----SAPEEKGWAKFTDFQPFCCSESG---PRCSS
PVDTECSHAEGSRSQGPEKA--------FSPASPCAWNVCVTRKAPLLASDSSSSGGSHS
EDGDQ-----KAASAMDAVSRGPGREAPPLPTVAR-TEEA----------------VGRV
GCA-DSRLLSPAC--PAPKEVTAAPAV--AVPPEATVAITTALSKAGPAIPTPAVSSALA
VAVPLGPIMAVTAAPA--------MVATLGTVTKDGKTDAP-PEGAALNGPV

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MFWK
FDLNTTSHIDKLLDKEHVTLQELMDEDDILQECKAQNQKLL-DFLCRQQCMEE---LVSL
ITKDPPLDMEEKVRFKYPNTACELLTCDVPQISDR-LGGDESLLNLLYDFLNQEPPLNPL
LASF--FSKTI

PF04499 // ENSGT00390000009899_2_Domain_0 (312, 569)

GSLIARKTEQVIMFLKKKDKFISLVLKHMGTSALMDLLLRLVSCVEPVG
LRQEVLHWLNEEKIIQRLVELIHPRQDEDRQSNASQALCDIVRLGRDQGSQLQEPV-ESD
PLLI-ALESQDCVEQLLKNMFDEDQTESCLVNGTQVLLALLEPRRTGT------------
------EG-LMDSFSQGLERS-YSVSSSVLQGIEPWLKNFHQLLLNPPKKKAILTTIGVL
EEPLGNARLHGARLMAALLHSNTPSINQ

ENSGT00390000009899_2_Linker_0_6 (569, 569)

PF04499 // ENSGT00390000009899_2_Domain_6 (569, 744)

ELCRLNTMDLLLDLFFKYTWNNFLHFQVELCI
AAILSHAAREEQTEASGSDGRA--EPLQGSGN-GNGKLETPQP-ITSLSENTMVTHLFQK
CCLVQRILEAWEANDHTQAAGGMRHGNMGHLTRIANAVVQNLERGPMHTHISE--VIQGL
PADCRGRWESFVEETLTETNRRNTVDL----------------------------AFSEY
QIQQMTANFVDQFGFNDEEFADQDDNINAPFDRIAEINFNIEADE--DNPSAALFEACCS
DRIQPFDD-----------EEEEDIWEDEETHCTARVMVRARFGAPHISENYSKNGLEPR
DQDRKADSEAISN-----------MPGAITPPTSLQNEGP-FSG-DSE-DTAWTAVFDEP
VNPT--PVATGTARDVGSSVWAAGP----SAPEEKSWAKFTDFQPFCCSESR---PRCSS
PVDMDCSHTNSSQSTNTEKAF--------GPTSPCSWNVCATRKAPLVASDSSSSGGSDS
EEDEK------ASGAVKAVCIGHSGEISPSP---R-TEEA---------------AITRT
EHA-DSNLLDPVH--LASSEVTVASVV--TVA--------TTQGKADPPINIPAVSSTVT
FAVHPGPIMAVSTVAAT-------TMATQGTVTKNRKTDVL-PEEAALNGPV

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MFWK
FDLNTTSHVDKLLDKEHVTLQELMDEDDILQECKAQNQKLL-DFLCRQQCMEE---LVSL
ITQDPPLDMEEKVRFKYPNTACELLTCDVPQISDR-LGGDESLLSLLYDFLDHEPPLNPL
LASF--FSKTI

PF04499 // ENSGT00390000009899_2_Domain_0 (312, 569)

GNLIARKTEQVITFLKKKDKFISLVLKHIGTSALMDLLLRLVSCVEPAG
LRQEVLHWLNEEKVIQRLVELIHPSQDEDRQSNASQTLCDIVRLGRDQGSQLQEAL-EPD
PLLT-ALESQDCVEQLLKNMFDGDRTESCLVSGTQVLLTLLETRRVG-------------
------TEGLVDSFSQGLERS-YTVSSSVLHGIEPRLKDFHQLLLNPPKKKAILTTIGVL
EEPLGNARLHGARLMAALLHTNTPSINQ

ENSGT00390000009899_2_Linker_0_6 (569, 569)

PF04499 // ENSGT00390000009899_2_Domain_6 (569, 744)

ELCRLNTMDLLLDLFFKYTWNNFLHFQVELCI
AAILSHAAREDRTEASGSESRA--EPLHENG---NRSLETPQP-PASLPDNTMVTHLFQK
CCLVQRILEAWEANDHTQAAGGMRRGNMGHLTRIANAVVQNLERGPVQTHISE--VIRGL
PADCRGRWESFVEETLTETNRRNTVDLVSTHHLHSSSEDEDIEGAFPNELSLQQ-AFSDY
QIQQMAASFVDQFGFNDEEFADQDDNINAPFDRIAEINFNIDADE--DSPSAALFEACCS
DRIQPFDD-----------DEDEDIWEDSDTRCATRAMARARFGAPHASDSCSKNGPEHG
GQDGKASSEAHGD-----------APGAGAPLAPGKKEAP-TVEGDSE-GAMWTAVFDEP
ANST--PTAPGVVRDVGSSVWAAGT----SAPEEKGWAKFTDFQPFCCSESG---PRCSS
PVDTERSRAEGSRSQGPEKA--------FSPASPCAWNVCVTRKAPLLASDSSSSGGSDS
-EDYQ-----KAASAVDAVSRSPGREAPPRPTGAR-TEEA----------------VSRA
ECA-NSRLLDPAC--PAPKEVTAAPAV--APPPEAAVAISTALSKAGPAIPSPAVSSAVA
VAVPLGPIMAVTTAPA--------MVATLGTVTKDRKRDAP-PEGAALNGPV

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MFWK
FDLSATSHVDKLLDKEGVTLRELMDGEDILQECKAQNRKLL-DFLCRRQSMEE---LVGL
VTQDPALDLEERARFKYPNTACELLTCDVPQINDR-LGGDETLLNVLYNFLDREPPLNPL
LASF--FSKTI

PF04499 // ENSGT00390000009899_2_Domain_0 (312, 569)

GNLIARKTEQVIAFLRKKDKFISLVLKHIGTSALMDLLLRLVSCVEPAG
LRQEVLHWLNEEKTIQRLVELIHPSQDEDRQSNASQTLCDIVRLGREQGSQLLEAP-QPD
PLLT-VLESQECVEQLLRNMFDGVQTELCLVSGTQVLLTLLEPRRAGS------------
-------EGLLDSCSQGLDRS-CTISPGVLHGIEPRLKDFHQLLLSPPKKAAILTSVGVL
EEPLGNARLHSARLVAALLHTGTPSINQ

ENSGT00390000009899_2_Linker_0_6 (569, 569)

PF04499 // ENSGT00390000009899_2_Domain_6 (569, 744)

ELCRLDTMGLLLDLFFKYTWNNFLHLQVELCI
AAILSHAAQEDRAAASGPEGVL--EPPPSSGD-----PATPQP-ASSLPESTMVTHLFQK
CCLVQRILEAWEANDHTQAAGGMRRGNMGHLTRIANAVVQSLEGGPLQSQVSE--AFRGL
PADCRGRWESFVEETLSEANRRNAVDLVSTHHLHPSSEDEDMEGVLPSELSLQQ-AFSEY
QVQQMTATFVDQFGFSDEEFAEQDDSVNAPFDRIAEISFSVDADD--DSPGAALFEACCS
DHIQPFDE-------------DDDLWEAEETHRAARV-TRARFGAPHASERCLKESPERR
GQGAGEGVDAA-------------------------QAGS-PCEGGSE-GSPWA-VPDGP
ATPMAASPAPAVALDVGSSVWAAGSP-STSAPEEKGWAKFADFQPFCCSESG---PRCSS
PVDTGHGDAQAGLNQGPERA-------------LGAWSTCVPRKASLVAASSR-------
-EDEQ-----KAAAASEAVGVGPSQKASPLSVLGP-RAD---------------------
-CA-PSSPP--GSVPLDPAEVPTASAE----------A-------TMTGPAPQAVSPVLA
VAVPPGPMVAVTTAAP--ASPAVSMAAALGTVPRDRQAGGPPPSGAALSGPV

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MFWK
FDLNTTSHVDKLLDKEDVTLRELLDEDDVLQECKAQNQKLL-GFLCRQQCMEE---LVSL
ITQDPPLDMEEKVRFKYPNTACELLTCDVPQINDR-LGGDETLLNLLYDFLDHEPPLNPL
LASF--FSKTI

PF04499 // ENSGT00390000009899_2_Domain_0 (312, 569)

GNLIARKTEQVILFLKKKDRFVSLVLQHIGTSALMDLLLRLVSCVEPAG
LRQEVLHWLNEEKIIQRLVELIHPSQDEDRQSNASQTLCDIVRLGREQASQLQEAP-EPD
PLLT-VLESQDCVEQLLKNMFDGDQTESCLVSGTQVLLTLLETRRAGT------------
------EG-LVDSFSQGLEGL-CTVSSSILHGIEPRLKDFHQLLLSPPKKKAILTTIGVL
EEPLGNARLHGARLMAALLHTNTPSINQ

ENSGT00390000009899_2_Linker_0_6 (569, 569)

PF04499 // ENSGT00390000009899_2_Domain_6 (569, 744)

ELCRLNTMGLLLDLFFKYTWNNFLHFQVELCI
AAILSHAAREDRAEASGLEGRV--ELLPGSGD-----PEAPQP-AASRPENTMVTHLFQK
CCLVQRILEAWEANDHAQAAGGMRRGNMGHLTRIANAVVQNLERGPMQTHISE--VIRGL
PADCRGRWENFVEETLAETNRRNAVDLVSTHHLHPSSEDEDMEGVFPNELSLQQ-AFSEY
QVQQMTATFVDQFGFNDEEFADQDDSVNAPFDRIAEINFSIDADE--DSPSAALFEACCS
DHIQPFDD-----------DEEDDIWEDKETHCTARVTARARFGGPHTSESCSKNGLERG
GQDRKEGLEADKD-----------VALAGAPLASAQKEGP-RLEGGSEAGASWA-VFEET
VNSP--VPVPGVAVDVGSGVWASSTP-SPSALEEKGWAKFTDFQPFCCSESG---PRCSS
PVDTGHGGAQDSLTQGPERT--------LGPASPCAWNACVTRKAPPVVSDNT-------
-EDEQ-----KMAGALETVSMGPSRETPLLPASVP----------------------RA-
-ECTASTLSDPTS--PAPAEATFTPAV--AVPPEAAVAATTAPGKASPAPAALPVAPVLS
GVVPTGPVAAVTTAAPS-----TCTAAILGTATKDRKMDAPPPAGATLNGPV