Query Results 

------------------------------------------------------------
----------MRRCGRL--SGPPSL----LLLLLLLSPLLFSGPGAYAARLSVLYSSSDP
LTLLDADSVR--PT

PF00085 // ENSGT00390000008045_0_Domain_0 (135, 222)

VL--GSSSAWAVEFFASWCGHC-------IAFAPT-----WKELAN
DVKDWRPALNLAVLDCAEETNSAVCREFNIAGFPTVRFFQA

ENSGT00390000008045_0_Linker_0_2 (222, 525)

FTKNGS---GATL---PGA
GANVQTLRMRLIDAL---ESHR-DTWPPACP-PLEPAKLNDIDGFFTRNKADYLALVFER
EDSYLGREVTLDLSQYHAVAVRRVLNTESDLVNKFGVTDFPSCYLLLRNGSVSRVP-VLV
ESRSFYTSYLRGLPGLTRDAPPTT-ATPV------TADKIAPTVWKFADRSKIYMADLES
ALHYILRVEVGKF--SVLEGQRLVALK-KFVAVLAKYFPGQPLVQNFLHSINDWLQKQQK
KRIPYSFFKA-ALDSRKE--DAVLTEKVNWVGCQGSEPHFRGFP

PF04777 // ENSGT00390000008045_0_Domain_2 (525, 628)

CSLWVLFHFLTVQANR
YSE-AHPQEPADGQEVLQAMRSYVQFFFGCRDCADHFEQMAAASMHQVRSPSNAILWLWT
SHNRVNARLSG-ALSEDPHFPKVQ--WPPRELCSACHN-ELNGQVPLWDLGATLNFLKAH
FSPANIVIDSSASRHTGR----RG--SPEATPELVMDTLKLES-RNS-VLGHEQAAS-A-
---ESPGATA-LDVPAEKPE--------ASGPQELYTGLRMG--GASPGQGPPERMEDH-
---QR-DMQENAPGQQHLSKRDTEALFLPEV---N-HLQGPLELR-RGGRSPKQLA----
---------------PILEEEP----EALAIQGQGQWLQVLGGGISHLDISLCVGLYSVS
FMGLLAMYTYFRARLRTPKGHASYPTA-

------------------------------------------------------------
----------MGWCGRR--SGP-----PP-PLLPL-PLLLLAAPGAGAAPRSALYSPSD

PF00085 // ENSGT00390000008045_0_Domain_0 (120, 250)

A
LTLLQADTLR--GAVL--DSRSAWAVEFFASWCGHC-------IAFAPT-----WKALAD
DVKDWRPALNLAALDCADETNSAVCRDFNIPGFPTVRFFKAFTKTGS---GTTV---PVA
GADVQTLRE

ENSGT00390000008045_0_Linker_0_2 (250, 527)

RLINAL---ESHS-VTWPPACP-PLEPARLEEIDGFFARNNEEYLALIFEK
EGSYLGREVTLDLSQRRGIAVRRVLNTETDVVSKFGVTNFPSCYLLFRNGSISRVP-VLV
ESRSFYTAYLQRFSENTREAAQTT-VPQT------TANTVAPTVWKVADRSKIYMADLES
ALHYILRVEVGKF--SVLEGQRLVALK-RFMAVLAQYFPGQPSVQNFLHSMNDWLRRQQR
KKIPYGFFQT-ALENRKE--GSVIAKKVNWVGCQGSEPHFRGFPCS

PF04777 // ENSGT00390000008045_0_Domain_2 (527, 627)

LWVLFHFLTVEAAR
KNV-DHSQEKAKAQEVLQAIRGYVRFFFGCQDCAGHFEQMAAASMHRVGSLDGAVLWLWS
SHNKVNARLAG-APSEDPQFPKVQ--WPPRELCSPCHN-ELRG-TPVWDLGNTLKFFKIH
FSQNNVVLDLPLARPGPR----RGAQRMAGSPQ-----MELA--TGNSTVVP-ENAEIVV
GRGSEPPGTFTLDVPVERLG--------AGGPQETQAGLGVT--GAGSDQGPAEHLVEL-
---QR-DQLEQPEGQRPLAKRDTGAILLAEFSAEKDLPGGPSELR-RVGRSSKQLA----
---------------SVPEREP----EAGAMRSRGRWLQVLEGDFSHLDISLCVVLYSLS
FMGLLAVYTCIRARMRTLKGHASHPAA-

------------------------------------------------------------
------------------------------------------------------------
-----------------------------------C-------IAFAPT-----WKALAN
DVKEWRPALNLAALDCADETNSAVCRDFNIPGFPSVRFFKAFSKNGL---GTTL---PVA
GANVQTLRERLIDAL---ESHH-DTWPPACP-PLEPAKLEEIDGFFARNNEEYLALIFEH
EGSYLGREVTLDLSQHRGVAVRRVLNTEDNVVRKFGVTDFPSCYLLFRNGSVSRVP-VLK
ESRSFYTAYLQRLSGITRETTPPT-AVPT------TPDKIAPTVWKFADHSKIYMADLES
ALHYILRVEVGKF--SVLEGQRLVALK-KFVAVLAKYFPGQPFVQNFLYSINDWLKRQQR
KKIPYSFFKT-ALDNRKE--DAVLTKKVNWIGCQGSEPHFRGFP

PF04777 // ENSGT00390000008045_0_Domain_2 (525, 628)

CSLWVLFHFLTVQASQ
QSA---SRELGNGQEVLQAIRSYVRFFFGCRDCANHFEQMASGSMHRVRSPDDAVLWLWT
SHNRVNARLAG-APSEDPQFPKVQ--WPPHELCSACHN-ELSG-EPVWDVGATLRFLKAH
FSPGNIVLHSPPPGPAPR----SSAHSLAAAPNPGVGALGPVT-RNS-TLGPEKADS-T-
---EPPGNTSMPDIPAERPE--------ASGPQLLHTGLQLS--GPVPRQGLPDHITEP-
---QR-AVLVQPQGQRHLSKRDTGAVLLAESWAEENHLHGPSELR-KGIHSSKQLA----
---------------SIPERER----EAQAVRVQGQWLQVLGRDFSHLDISLCVGLYSLS
FMGLLAMYTYFRARMKVLKGHAIHLAA-

------------------------------------------------------------
----------MGRCGR-G-SGPLPSLL----L---LLLLLLAVPGAGAAPRSALYSPSDP
LTLLQADTVR-

PF00085 // ENSGT00390000008045_0_Domain_0 (132, 225)

-GAVL--GSRGAWAVEFFASWCGHC-------IAFAPT-----WKALAE
DVKAWRPALNLAALDCAEETNSAVCRDFNIPGFPTVRFFKAFSK

ENSGT00390000008045_0_Linker_0_2 (225, 525)

NGS---GAVF---PVA
GADVQTLRERLIDAL---ESHH-DMWPPACP-PLEPAKLEEIDGFFARNKEEYLALIFEK
GGSYLGREVALDLSQHKGMAVRRVLNTEADVVRKFGVTDFPSCYLLFRNGSVSRVP-VLM
ESRSFYTAYLQRLSGLTREAAQTT-VAPT------TANKIAPTVWKFADRSKIYMADLES
ALHYILRIEVGRF--PVLEGQRLVALK-KFVAVLAKYFPGQPLVQNFLHSVNEWLKRQKR
NKIPYSFFKT-ALDDRKE--GAVLAKKVNWIGCQGSEPHFRGFP

PF04777 // ENSGT00390000008045_0_Domain_2 (525, 628)

CSLWVLFHFLTVQAAR
QNV-DHSQEAAKAQEVLPAIRGYVHYFFGCRDCAGHFEQMAAASMHRVGSPNAAVLWLWS
SHNRVNARLAG-APSEDPQFPKVQ--WPPRELCSACHN-ERLD-VPVWDVEATLNFLKAH
FSPSNIILDFPAAGSAAR----RDAQNVAAAPELAMGALELEG-RNS-TLDPGKPEM-M-
---K-PPANTTPDVPAERPE--------ASRPPKLRPGLG-----AAPGQEPPEHMAEL-
---QR-NEREQPRGQWHLSKRDTGAALLAESLAEKNRLWGPPEVR-RVGRSSKQLV----
---------------DLPEGQL----EAQAGRGRGQWLQVLGGGFSHLDISLCVGLYSLS
FMGLLAMYTYFRAKIRALKGHAGHPAA-

------------------------------------------------------------
----------MGWCGRG--SGP-----PP-SRLLMLLSLLLAVRGAGAAPRSALYSSSDP
LTLLR

PF00085 // ENSGT00390000008045_0_Domain_0 (126, 225)

ADTVR--STVL--GSSSAWAVEFFASWCGHC-------IAFAPT-----WKALAX
VISDWRPALNLAALDCAEETNSAVCRDFNIPGFPTVRFFKAFSK

ENSGT00390000008045_0_Linker_0_2 (225, 525)

TGS---GTTL---SVA
GADVQTLRERLIDAL---ESHS-DTWPPACP-PLEPARLEEITGFFARNNEEYLALIFEK
EGSYLGREVTLDLSQHQGIAVRRVLNTERDVVNRFGVTNFPSCYLLSRNGSFSRVP-ALT
ESRSFYTTYLRKFSGSTRGAVQTT-AAPA------TTSAVAPTVWKVADRSKIYMADLES
ALHYILRIEVGKF--SVLEGQRLVALK-KFMAVLAKYFRGRPLVQNFLHSMNDWLKKQQR
KKIPYGFFKN-ALDSRKE--GTVIAEKVNWVGCQGSEPHFRGFP

PF04777 // ENSGT00390000008045_0_Domain_2 (525, 628)

CSLWILFHFLTVQAAQ
EGV-DHPQERAKAQEVLQAIRGYVRFFFGCRECAGHFEQMASGSMHRVGSLNSAVLWFWS
SHNKVNARLAG-APSEDPQFPKVQ--WPPRELCSACHN-ELRG-TPVWDLDNILKFLKTH
FSPSNIVLDFPSAGPGPW----RGAERMAVIPKQLI------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------

------------------------------------------------------------
----------MRRCGRH--SGSPSQ-----MLLLLLPPLLLAVPGAGAVQVSVLYSSSDP

PF00085 // ENSGT00390000008045_0_Domain_0 (121, 224)

VTVLNANTVR--STVL--RSNGAWAVEFFASWCGHC-------IAFAPT-----WKELAY
DVREWRPVLNLAVLDCAEETNTAVCRDFNISGFPTVRFFKAFS

ENSGT00390000008045_0_Linker_0_2 (224, 525)

KNGS---GITL---PVA
DASVETLRRKLIDAL---ESHS-DMWSSSRP-KLKPAKLVEINEFFAETNEDYLVLIFED
KDSYVGREVTLDLFQHH-IPVHRVLNTERNAVSKFGVVEFPSCYLLFRNGSFSRVP-VVM
ESRLFYTSYLKGMSGPILVDPPTT-TI--------ITTDVVPTVWKVAN--QIYMADLES
SLHYIFLVEVGKF--SVLEGQRLLALK-KLVAVLAKYFPGRPLAQNFLHSIHDWLQRQQR
KKIPYKFFRA-ALDNRKE--GIVLTEKVNWVGCQGSKPHFRGFP

PF04777 // ENSGT00390000008045_0_Domain_2 (525, 628)

CSLWILFHFLTVQASR
YSE-NHPQEPADGQEVLQAMRSYVQWFFGCRDCAEHFENMAASTMHRVRSPTSAVLWLWT
SHNKVNARLSG-APSEDPYFPKVQ--WPLRELCFDCHN-EINGREPVWDLEATYRFLKAH
FSSENIILDTPVAGLATQ----RNPQILGATPEPVMDALELET-RNS-VLGHERAAS---
---TESPGATALNVPVGKPE--------ASGPQALYT-----------GQGPPEHMEEP-
---QR-VTQGHTQGQQHLSKRDTEVLTLPE----VNHLQGPLELR-RGGRSPKQLV----
---------------NIPEGEP----EAPAIRGQGPWLQVLGRGFSHLDISLCVGLYSVS
FVCLLAMYTYFRARLRTPKGHLVTQ---

------------------------------------------------------------
----------MGRCNR-G-SGPPPSLL-------LLLLWLLAVPGANAAPRSALYSPSDP
LTLLQADTVR--G

PF00085 // ENSGT00390000008045_0_Domain_0 (134, 223)

AVL--GSRSAWAVEFFASWCGHC-------IAFAPT-----WKALAE
DVKAWRPALYLAALDCAEETNSAVCRDFNIPGFPTVRFFKAF

ENSGT00390000008045_0_Linker_0_2 (223, 525)

TKNGS---GAVF---PVA
GADVQTLRERLIDAL---ESHH-DTWPPACP-PLEPAKLEEIDGFFARNNEEYLALIFEK
GGSYLGREVALDLSQHKGVAVRRVLNTEANVVRKFGVTDFPSCYLLFRNGSVSRVP-VLM
ESRSFYTAYLQRLSGLTRDAAQTT-VAPT------TANKIAPTVWKFADRSKIYMADLES
ALHYILRIEVGRF--PVLEGQRLVALK-KFVAVLAKYFPGRPLVQNFLHSVNEWLKRQKR
NKIPYSFFKT-ALDDRKE--GAVLAKKVNWIGCQGSEPHFRGFP

PF04777 // ENSGT00390000008045_0_Domain_2 (525, 628)

CSLWVLFHFLTVQAAR
QNV-DHSQEAAKAKEVLPAIRGYVHYFFGCRDCASHFEQMAAASMHRVGSPNAAVLWLWS
SHNRVNARLAG-APSEDPQFPKVQ--WPPRELCSACHN-ERLD-VPVWDVEATLNFLKAH
FSPSNIILDFPAAGSAAR----RDVQNVAAAPELAMGALELES-RNS-TLDPGKPEM-M-
---K-SPTNTTPDVPAEGPE--------ASRPPKLRPGLG-----AAPGQEPPEHMAEL-
---QR-NEQEQPLGQWHLSKRDTGAALLAESRAEKNRLWGPLEVR-RVGRSSKQLV----
---------------DIPEGQL----EARAGWGRGQWLQVLGGGFSYLDISLCVGLYSLS
FMGLLAMYTYFQAKIRALKGHAGHPAA-

------------------------------------------------------------
--------------------------------------------------IKTCDSGSMP
L--------P--GLVSGGGDTVLWALVRV-ECCTLG-------ISRRRSRSLLLHLISLL
PLADWRPALNLAALDCAEETNSEVCRDFNIPGFPTVRVRDR----------EGR---EVA
GADVETLRKRLIDAL---ESHS-DTWPPACP-PLEPARLEEIDGFFARNDEEYLALIFEK
AGSYLGREVTLDLSQHHGIAVRRVLNTEGDVVSKFGVTDFPSCYLLFRNGSASRVR-VLK
ESRSFYTAYLQKFSRTTREAVPTT-VAPT------TAHTAAPTVWKVADRSKIYMADLES
ALHYILRVEVGKF--SVLEGQRLVALK-KFMAVLAQHFPGQPLVQNFLHSMNDWLKRQQR
KKIPYGFFKA-ALDNRKE--GAVIVKKVNWVGCQGSEPHFRGFP

PF04777 // ENSGT00390000008045_0_Domain_2 (525, 628)

CSLWLLFHFLTVQAAR
HNL-DHSHEAAKAQEVLQAIRGYVRFFFGCRDCASHFEQMAAASMHRVESLNSAVLWLWS
SHNKVNARLAG-APSEDPHFPKVQ--WPPRELCSACHN-ELRG-SPVWDLDNTLRFLKTH
FSPSNVVLDLPSAGPGPR----MVAQRMA---------------ARNFTLGP-EKAGVMV
GPG-----TTVPKVPAETLR--------VSHPRDVLIGLSM---TAEPDQGPPEHIAEL-
---HR-DTLERPKGREHLTKRDTGAVLLAEFLAEKN-PGGPAELG-RVGRSSKQLA----
---------------SISDGEL----EAGPVRGRDQWLQVLGGGFSHLDISLCVGLYSLS
FMGLLAVYTYFRARMRALKGHAGHPTA-

------------------------------------------------------------
----LGSPTDHRKCGR-G-SGPLPSLL----L---LLLLLLAVPGAGAAPRSALYSPSDP
LTLLQADTVR--G

PF00085 // ENSGT00390000008045_0_Domain_0 (134, 223)

AVL--GSRGAWAVEFFASWCGHC-------IAFAPT-----WKALAE
DVKAWRPALNLAALDCAEETNSAVCRDFNIPGFPTVRFFKAF

ENSGT00390000008045_0_Linker_0_2 (223, 525)

SKNGS---GAVF---PVA
GADMQTLRERLIDAL---ESHH-DTWPPACP-PLEPAKLEEIDGFFARNKEEYLALIFEK
GGSYLGREVALDLSQHKGVVVRRVLNTEADVVRKFGVTDFPSCYLLFRNGSVSRVP-VLM
ESRSFYTAYLQRLSGLTREAAQTT-VAPT------TANKIAPTVWKFADRSKIYMADLES
ALHYILRIEVGRF--PVLEGQRLVALK-KFVAVLAKYFPGRPLVQNFLHSVNEWLKRQKR
NKIPYSFFKT-VLDDRKE--GAVLAKKVNWIGCQGSEPHFRGFP

PF04777 // ENSGT00390000008045_0_Domain_2 (525, 628)

CSLWVLFHFLTVQAAR
QNV-DHSQEAAKAQEVLPAIRGYVHYFFGCRDCAGHFEKMAAASMHRVGSPNAAVLWLWS
SHNRVNARLAG-APSEDPQFPKVQ--WPPRELCSACHN-ERLD-VPVWDVEATLNFLKAH
FSPSNIILDFPAAGSAAR----RDAQNVAAAPELAMGALELEG-RNS-TLDPGKPEM-M-
---K-SPANTTPDVPAERPE--------ASRPPKLRPGLG-----AAPGQEPPEHMAEL-
---QR-NEREQPRGQWHLSKRDTGAALLAESRAEKNRLWGPSEVR-RVGRSSKQLV----
---------------DIPEGQL----EARAGRGRGQWLQVLGGGFSHLDISLCVGLYSLS
FMGLLAMYTYFRAKIRALKGHAGHPAA-

------------------------------------------------------------
----------MGSCGRG--SGP-----PL-SL--LLLAVLLAVPGAGAAPRSALYSSSDP
LTLLQADTVR--G

PF00085 // ENSGT00390000008045_0_Domain_0 (134, 221)

AVL--GSRSAWAVEFFASWCGHC-------IAFAPT-----WKALAN
DVKDWRPALNLAALDCAEETNNAVCREFDIPGFPTVRFFK

ENSGT00390000008045_0_Linker_0_2 (221, 525)

AFSRTGS---GATL---PVA
GADVQTLRERLIDAL---ETHS-DTWPPACP-PLEPARLEEITGFFARNSEEYLALIFEK
EGSYLGREVALDLSQRQGIAVRRVLNTERNVVSKFSVTDFPSCYLLFRNGSFSRVP-VLM
ESRSFYTAYLQRLSGVIRKPVPTT-TVPT------TTRTVAPTVWKVADPSKIYMADLES
ALHYILRVEVGKF--SVLEGQRLVALK-KFVAVLAQYFPGQPLVQNFLHSVNDWLKKQPR
KKIPYGFFKT-VLDNRKE--GAVIADKVNWVGCQGSEPHFRGFP

PF04777 // ENSGT00390000008045_0_Domain_2 (525, 628)

CSLWILFHFLTVQASR
QSV-DPSQETAKAQEVLQAIRGYVRFFFGCRDCAAHFEKMASGSMHRVGSPNSAVLWLWS
SHNKVNARLAG-APSEDPQFPKVQ--WPPRELCPACHN-ELRG-APVWDLGNSLNFLKTH
FSPSNIVLDLPSARLGPQ----RGAQRMAVNPEQVE--LELA--AGNFTLGPPEKVEIML
GPGTESPGATIPDVPAE-----------E---------PGAS--HPQERQDPPEYIAEL-
---QR-DELEQPVGQQRLTRRDTGAVLLAEFLAEKTLPRGPSELR-RVGRSSKQLA----
---------------SIPDGEP----KPGAMPGRGQWLQVLEGNFSHLDISLCVGLYSLS
FMGLLAAYTYFRARIRALKGHASHPAA-

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---EWRPA

PF00085 // ENSGT00390000008045_0_Domain_1 (189, 221)

VILAAIDCADEANQQVCASFGITGFPTLKFFR

ENSGT00390000008045_0_Linker_1_2 (221, 527)

AFTKKAED--GIRI---ANP
AATVTELRRAIITNL---EQSL-DAWPPACP-PLEPASAEEVHSFFQRNGEQYLALIFEN
SDSFVGREVILDLLQYENVAVRRVLSSEEELVQKFGVTTFPSGYLLLRNGSFSRLP-VHL
EARSFYTYYLRTLSGVTRGSYRLHDAAPP------GHRAERRRASRCAPSSKVYMADLES
ALHYSLRVEAGRP--ATLSGAQLAAFK-CYVATLAKYFPGRPCVQSYLQTLDGWLKLDGA
RAAPQR---PEGGGEEQASPPAVLPTNVTWVGCRGSEPHFRGYPCG

PF04777 // ENSGT00390000008045_0_Domain_2 (527, 627)

LWTVFHLLTVQAAQ
GGP-----DKELPLEVLGTMRCYVKHFFGCQECAQHFEAMAAKSMDQVKGRDEAVLWLWS
HHNEVNARLAG-GDTEDPQFPKLQ--WPPPDMCPQCHK-EERG-VHAWDELAVLSFLKTF
FSPGNIDLDYAVPALRGGGGTRGSHLRLVSTPHPPL------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------

------------------------------------------------------------
----------MGRCNR-G-SGPPPSLL----LLL---LLLLAVPGASAAPRSALYSPSDP
LTLLQADTVR--G

PF00085 // ENSGT00390000008045_0_Domain_0 (134, 223)

AVL--GSRSAWAVEFFASWCGHC-------IAFAPT-----WKALAE
DVKAWRPALNLAALDCAEETNSAVCRDFNIPGFPTVRFFKAF

ENSGT00390000008045_0_Linker_0_2 (223, 525)

SKNGS---GAVF---PVA
GADVQTLRERLIDAL---ESHH-DTWPPACP-PLEPAKLEEIDGFFARNNEEYLALIFEK
GGSYLGREVALDLSQHKGVAVRRVLNTEADVVRKFGVTDFPSCYLLFRTALSPESPCELM
ESRSFYTAYLQRLSGLTREAAQTT-VAPT------TANKIAPTVWKFADRSKIYMADLES
ALHYILRIEVGRF--PVLEGQRLVALK-KFVAVLAKYFPGRLLVQNFLHSVNEWLK----
-----SFFKT-ALDDRKE--GAVLAKKVNWIGCQGSEPHFRGFP

PF04777 // ENSGT00390000008045_0_Domain_2 (525, 628)

CSLWVLFHFLTVQAAR
QNV-DQSQEAAKAQEVLPAIRGYVHYFFGCRDCAGHFEQMAAASMHRVGSPNAAVLWLWS
SHNRVNARLAG-APSEDPQFPKVQ--WPPRELCSACHN-ERLD-VPVWDVEATLNFLKAH
FSPSNVILDFPAAGSAAR----REAQNVAAAPELAMGALELES-QNS-TLYPGKPEM-M-
---K-SSTNTTPDVPAERPE--------ASRPPKLRPGLG-----AAPGQEPPEHMAEL-
---QR-DEREQPRGQWHLSKRDTGAALLAESRAEKNRLWGPSEVR-RVGRSSKQLV----
---------------DIPEGQL----EARAGRGRGQWLQVLGGGFSYLDISLCMGLYSLS
FMGLLAMYTYFRAKIRALKGHAGHPAA-

------------------------------------------------------------
----------LAAAGRG--SGPPSPLWLP-------LLMLMAVPVAGAARLSALYSPSD

PF00085 // ENSGT00390000008045_0_Domain_0 (120, 254)

P
LTLLQADTVR--GAVL--GSPSAWAVEFFASWCGHC-------IAFAPT-----WRALAN
DIKDWRPALNLAALDCAEETNSAVCRDFNILGFPTVRFFKAFSKSDS---GTPL---SVA
GADVQTLRERLID

ENSGT00390000008045_0_Linker_0_2 (254, 527)

AL---ETHQ-DTWPAACP-PLEPARLEEINGFFARNDEDYLALIFEK
EGSYLGREVTMDLSQRQGLAVRRVLNTEEKVVNKFGVTDFPSCYLLFRNGSVSRVP-VLV
ESRSFYTAYLQRLSGVTREPSQTT-VVPT------TANTIAPTVWKRADHSKIYMADLES
ALHYILRVEVGKF--PVLEGQRLTALK-KFVAVLAKYFPGRPLVQNFLRSTNDWLKRQQR
KKIPYSSFKA-ALDNRKE--GAVIAKKVNWVGCQGSEPHFRGFPCS

PF04777 // ENSGT00390000008045_0_Domain_2 (527, 627)

LWILFHILTVQATR
QNL-YHPQGTAKPQEVLQAIRGYVRNFFGCRVCAGHFEQMAAASMHQVNSLDGAVLWLWA
SHNKVNARLAGKCPSEDPHFPKVQ--WPTRELCSACHN-ELQG-EPEWNLDATLRFLKAH
FSPSNIVLGLPQAGPDLR----RDRERKASALQLVTGALELAT-GNP-TLGPEEAAV-T-
---VGPGTES-PSVPAEKSG--------ASRFQEPSPGLGMT--GAAPDQGPPENVAGH-
---PR-DELEQLQGQRRLSKRDTGAVLLAEFMAEKDHLRGPLELR-RVGRNSKQLA----
---------------SVPEGEP----EAGARQGRGQWLQVLEGGFSHLDISLCVGLYSLS
FMGLLAVYTYFRARMRALKGRASHTAA-

------------------------------------------------------------
--MGRRGRCSAATMGPG--SGS--GALRRPLGLLLL-AALLVPAAGAARLRAMLYSAQDP
LV

PF00085 // ENSGT00390000008045_0_Domain_0 (123, 225)

LLTDSSLK--STVL--GSPSSWVVEFFASWCGHC-------IAFAPK-----WKALAN
EVKDWRPVISVAALDCAEEANSEICRDFGIMAYPTVKYFKAFSD

ENSGT00390000008045_0_Linker_0_2 (225, 525)

SSSL--GTEF---SVS
GKSVEELQASLIDAL---ETHRGGRWPPSCP-PLSPIRLDEINSFFLRNSDDYLAVIFEK
KDSYLGREVELDLSQYHGIKVRRALDVQEDLVKKFAVTNFPSCYLLSGNGSSFKVP-VLM
ESRSLYSTYLQKLPGVGKKSLTPT-VHPN------TSERIAPPVIKPIDRSKIYMLDLES
TLHYILRIEVGKF--KVLEGERLTALK-NFVSVLAKYYPGQPVVRNFLHTIDVWLHWQQR
KSVPYSSLEV-ALNSWKE--GVLLPKKSVWVGCQGSEAHFRGFP

PF04777 // ENSGT00390000008045_0_Domain_2 (525, 628)

CGLWILFHSLTVQAAQ
HNEY-LQQKAEDPQEVLQAIRGYVKFFFGCRECATHFEQMAAASMYRVKSMDDAVLWFWN
RHNRVNARLAG-TASEDPQFPKIQ--WPPRDLCNPCHN-EVQG-DPVWNLGAILKFFKNH
FALRNIVITSRNPSMEAL----PGPGRLPE---------EL----ENFTAPPPVEQP---
HPTESPGEQPVHECRAESLDEEVQPLIQYSRPESLDEEVQPP----IQYGGAESPMLGH-
---GFAELFPKPQIAQKLTKRDTLAQQVEEG-----------------AGKVKQLA----
---------------SFHERKVG-----ARAQLGSQWLWRLRGSFSYLDVGLCIGLYSLS
FLCLMTMCTYFQERMKVRKSRASSSSA-

------------------------------------------------------------
----------MRRCGRC--SAPPPS------LLLLLLPLLLAAPGTGAAPRSALYSPSD

PF00085 // ENSGT00390000008045_0_Domain_0 (120, 237)

P
LTLLQADTVR--RAVL--GSRSAWAVEFFASWCGHC-------IAFAPT-----WKAVAN
DVKDWRPALNLAALDCADESNSAVCRDFNIAGFPTVRFFQAFSKNVP---GTTLPX

ENSGT00390000008045_0_Linker_0_2 (237, 550)

X---
XXXXXXXXXXXXXXL---EFPR-ETCHQSCP-PLELAKLEEIEGFFARNDEEYLALIFEK
EGSYLGREVTLDLSQRHGLAVRRVLNTEGNVVSKFGVTDFPSCYLLFRNGSVSRVP-VLV
ESRSFYTAYLQRLSGLTREAAEAT-AVPT---AA-KTIA--PTAWKLAD--RXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXX-XXXXXXX--XXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXX

PF04777 // ENSGT00390000008045_0_Domain_2 (550, 627)

XXNAQEVLQAIRGYVRYFFGCRDCANHFEQMAAASMNRVASLNDAVLWLWS
GHNKVNARLAG-APSEDPQFPKVQ--WPPRELCSACHN-EVQG-PPVWDVAATLNFLKTH
FSPSNVVMNFPHNRLAPR----HGAQVLADTPGLVMGVLDLAV-GNS-TLRPEGAET---
---AELQGTFVPEVPVWRPK--------ASPPQELHAGRGPE--------GPPELPAVP-
---QE-AELEPLQGLRRLSKRDIGAV-LAEPWAGKNHLGDPAEPR--YLRSSKQLA----
---------------SMPEGKP--------KSPGGPWLQVLGGGFSHLDISLCVGLYSLS
FLGLLADYTSFRARMRALKGHSSHPAA-

------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------------KALAE
DVKAWRPALNLAALDCAEETNSAVCRDFNIPGFPTVRFFKSFSKNSS---GAAF---PVA
GADVRTLRERLIDAL---ESHH-DTWPPACP-PLQPAKLKEIDGFFARNKEEYLALIFEK
GGSYLGREVALDLSQHKGVAVRRVLNTEADVVRKFGVTNFPSCYLLFRNGSVSRVP-VLM
ESRSFYTAYLQRLSGLPREASQTT-VAPT------TVKKIAPTVWKFADRSKIYMADLES
ALHYILRIEVGRF--SVLEGQRLVALK-KFVAVLAKYFRGQPLVQNFLHSVNEWLKRQKR
RKIPYSFFKT-ALDDRKE--GDVLAKKVNWIGCQGSEPHFRGFP

PF04777 // ENSGT00390000008045_0_Domain_2 (525, 628)

CSLWVLFHFLTVQAAR
QPV-DHSQEAATAQEVLQAVRGYVRFFFGCRDCAGHFEQMAAASMDQVGSPDAAVLWLWS
SHNKVNARLAG-APSEDPQFPKVQ--WPPRELCSACHN-ERLD-VPVWDVEATLTFLKAH
FSPSNIVLGFPAAGSAPR----WDAQRMAAAPKLAMEGLELES-RNS-TLDPEKPEI-M-
---I-PPANTTPDVPAERPK--------ASHPPKLRPGLG-----ATPGQGPPEHMAEL-
---QR-NEREQPRGQWHLNKRDTGAALLAESQAEKNRLWGPLEVR-HVGRSSKQLV----
---------------HIPEGQL----EAGARQGRGQWLQVLGGGFSHLDISLCVGLYSLS
FVGLLAMYTYFRAKIRALKGHAGYPVA-

------------------------------------------------------------
----------MRRCGRG--CGPPPSLL--------LLLLLLAVPGAGAAPRSALYSPSDP
LTLLRADSVR-

PF00085 // ENSGT00390000008045_0_Domain_0 (132, 221)

-HAVL--GSRSAWAVEFFASWCGHC-------IAFAPI-----WKALAK
DVKDWRPALNLAALDCADETNIAVCRDFNILGFPTVRFFK

ENSGT00390000008045_0_Linker_0_2 (221, 525)

AFSKDGL---GATL---PVA
GADVQTLRERLIDAL---GSHR-DTWPLACP-PLEPAKLEEIDGFFARNNAEYLALIFEK
EGSYVGREVTLDLSQHHGMVVRRVLNTEDDVVKKFGVTHFPSCYLLFRNGSVSQVP-VLM
ESRSAYTTYLQSLSGPTREAAPTS-VAPT------TAKKIAPTVWKLADHSKVYMADLES
ALHYILRVEVGKF--SVLEGQRLVALK-KFVAVLAQYFPGQPLVQNFLHSVNEWLKKQQR
KKIPYSFFKT-ALDNRKE--GAVLAKKVNWVGCQGSEPHFRGFP

PF04777 // ENSGT00390000008045_0_Domain_2 (525, 628)

CSLWVLFHFLTVQASQ
HSA-GHPQEKAQAQEVLQAIRGYVRFFFGCRDCASHFEQMAAGSMQQVESLDQAVLWFWS
SHNRVNARLAG-APSEDPQFPKVQ--WPPRELCSACHN-ELRG-EPVWDVDATLHFLKAH
FSPSNIVLALPRAGPGAQ----RGMQELAAVPKLVMGALELGT-RNS-SLGPEMDKV-T-
---RSPGNIVMA-VLAERPE--------LTGNPIP-CSLGPQ--SLLLGFGPVL------
----G-HVKPQ------------EGPLNWVSWGGT-PPYT--------------------
------------------------------------------------------------
----------------------------

------------------------------------------------------------
----------MTGCGRR--SGW------LPPLRLLLLPLLLGGPGVGAAQLAALYSASDP
LTLL

PF00085 // ENSGT00390000008045_0_Domain_0 (125, 225)

QADTVR--STVL--NSPSAWAVEFFASWCGHC-------IAFAPT-----WKALAK
DIKDWRPALNLAALNCADETNNAVCRDFNIAGFPSVRFFKAFSK

ENSGT00390000008045_0_Linker_0_2 (225, 525)

NST---GTTL---PVA
GANVQMLRERLIDAL---ESHH-DTWPSACP-PLEPVKPKEIDTFFARNNQEYLVLIFEQ
ENSYLGREVTLDLSQHHDLVVRRVLSTEANVVRKFGVADFPSCYLLFRNGSVSRVP-VLV
ESRRFYTAYLQRLSEVTREGTPTP-AVPT------ISDQIAPTVWKFADRSKIYMADLES
ALHYILRVEVGRF--SVLEGQRLMALK-KFVTVLTKYFPGQPLVRNFLQSTNEWLKRQHK
KKMPYSFFKT-AMDSRNE--EAVITKEVNWVGCQGSESHFRGFP

PF04777 // ENSGT00390000008045_0_Domain_2 (525, 628)

CSLWILFHFLTVQASQ
KNA-ESSQKPANGQEVLQAIRNYVRFFFGCRDCANHFEQMAAGSMHRVKSPNDAVLWLWT
SHNRVNARLAG-APSEDPQFPKVQ--WPPPELCSACHN-ELSG-EPVWDVDATLRFLKTH
FSPSNIVLNFPPAEPASR----SSVHSWGATPHLELDALGLVT-RNS-ALALERAEI-S-
---ESPGSNAMPNIPAERPE--------------LFEALSHS--R---------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------

------------------------------------------------------------
----------MGRCGR-G-SGPLPSLL----L---LLLLLLAVPGAGAAPRSALYSPSDP
LTLLQADTVR--G

PF00085 // ENSGT00390000008045_0_Domain_0 (134, 223)

AVL--GSRGAWAVEFFASWCGHC-------IAFAPT-----WKALAE
DVKAWRPALNLAALDCAEETNSAVCRDFNIPGFPTVRFFKAF

ENSGT00390000008045_0_Linker_0_2 (223, 525)

SKNGS---GAVF---PVA
GADMQTLRERLIDAL---ESHH-DTWPPACP-PLEPAKLEEIDGFFARNKEEYLALIFEK
GGSYLGREVALDLSQHKGVVVRRVLNTEADVVRKFGVTDFPSCYLLFRNGSVSRVP-VLM
ESRSFYTAYLQRLSGLTREAAQTT-VAPT------TANKIAPTVWKFADRSKIYMADLES
ALHYILRIEVGRF--PVLEGQRLVALK-KFVAVLAKYFPGRPLVQNFLHSVNEWLKRQKR
NKIPYSFFKT-VLDDRKE--GAVLAKKVNWIGCQGSEPHFRGFP

PF04777 // ENSGT00390000008045_0_Domain_2 (525, 628)

CSLWVLFHFLTVQAAR
QNV-DHSQEAAKAQEVLPAIRGYVHYFFGCRDCAGHFEKMAAASMHRVGSPNAAVLWLWS
SHNRVNARLAG-APSEDPQFPKVQ--WPPRELCSACHN-ERLD-VPVWDVEATLNFLKAH
FSPSNIILDFPAAGSAAR----RDAQNVAAAPELAMGALELEG-RNS-TLDPGKPEM-M-
---K-SPANTTPDVPAERPE--------ASRPPKLRPGLG-----AAPGQEPPEHMAEL-
---QR-NEREQPRGQWHLSKRDTGAALLAESRAEKNRLWGPSEVR-RVGRSSKQLV----
---------------DIPEGQL----EARAGRGRGQWLQVLGGGFSHLDISLCVGLYSLS
FMGLLAMYTYFRAKIRALKGHAGHPAA-

------------------------------------------------------------
----------MRRCGRS--CGPPPSLL------LLL-LLLLPVPGARAARRSALYSPSDP
LTLLQAD

PF00085 // ENSGT00390000008045_0_Domain_0 (128, 224)

TVR--GAVL--DSRSAWAVEFFASWCGHC-------IAFAPT-----WKALAS
DVKDWRPALNLAALDCADENNSAVCRDFNIPGFPTVRFFKAFS

ENSGT00390000008045_0_Linker_0_2 (224, 525)

KNGS---GATL---PVA
RADVQTLRERLVDAL---ETHR-DMWPPACP-PLEPAKLADIDGFFARNTEDYLALIFEK
EGSYLGREVTLDLSQHRGIAVRRVLNTEDSVVRKFGVTDFPSCYLLFRNGSVSRVS-VMV
ESRSFYTDYLKRLSGLTREAARTA-VTPT------TARTVAPTVWKFADRSKIYMADLES
ALHYILRVEVGKF--SVLEGQRLVNLR-KFVAVLAKHFPGSPLVQNFLYSVNDWLKRQQR
KKIPYGLFKT-ALDNRKE--GAVLAERVNWVGCQGSEPHFRGFP

PF04777 // ENSGT00390000008045_0_Domain_2 (525, 628)

CSLWLLFHVLTVQAAR
HKA-DPPQEAAQAQEVLQAIRGYVRSFFGCRDCADHFEQMAAASMHRVGSLDDAVLWFWS
SHNKANARLAG-APSEDPHFPKVQ--WPPRELCSACHN-ELTG-PPVWDVAATLSFLKAH
FSPSNIVLDAPLAGPAPR----SGTQNLAASPKLAMEALELET-GNS-TLGPDKAEA-A-
---TSPGATVPDVPAAERPE--------ASRTPELHAS--------SEGQRAPESRAEL-
---WRGEEQGQPPELRHLSKRDAGAASLAELGPEKSGPGGPGGPR-RIGRSSKQLA----
---------------DVAAWEL----EARAPQGRGPWLQVLGGGFSHLDVGLCVGLYALS
FVALLGLYTFFRAKMRASKGPAGHPAA-

------------------------------------------------------------
----------SRPCGVM--MITDPETFPL-LSHLLLTHILLRVGI-PRTFLSALYSSSD

PF00085 // ENSGT00390000008045_0_Domain_0 (120, 254)

P
LTLLQADTVR--GAVL--GSSSAWAVEFFASWCGHC-------IAFAPT-----WKALAN
DVKDWRPALNLAALDCADETNSAICRDFNIPGFPTVRFFKAFSKNGS---GATL---PVA
GADVETLRKRLID

ENSGT00390000008045_0_Linker_0_2 (254, 527)

AL---ESHG-DTWPPACP-PLEPARMEEIDGFFARNDEDYLALIFEK
EGSYLGREVTLDLSQHRGIAVRRVLNTEGDVVSKFGVTDFPSCYLLFRNGSASQVH-VLV
ESRSFYTAYLQRFSRAPRESVPTK-VVPT------TAHTVAPTVWKVADRSKIYMADLDS
ALHYVLRVEVGKF--SVLEGQRLVALK-KFMAVLAQHFPGQPLVQNFLHSINDWLKRQQR
KKIPYSFFKA-ALDNRKE--GTVVAKKVNWVGCQGSEPHFRGFPCS

PF04777 // ENSGT00390000008045_0_Domain_2 (527, 627)

LWILFHFLTVQAAR
HNL-DHSQETAKAQEVLQAIRGYVRFFFGCRDCASHFEQMAAASMHRVESLNSAVLWLWS
SHNKVNARLAG-AASEDPHFPKVQ--WPPRELCSPCHD-ELRG-TPVWDLSNTLRFLKTH
FSPSNVVPDMPSARLGPR----MVAQRMA---------------AGNFTLGP-EKEGIMV
GPGTKSPGPTVPDVPAERLR--------ASHPQDMLTGLGTA--PAEPDQGPPEHIAEL-
---QR-DKVEAPKGQQHLTKRDTGAVLLAEFLAEKNLPRGPSELR-RVGRSSKQLA----
---------------SIPEGEP----EAGPVRGQDQWLQVLEGNFSHLDISLCVGLYSLS
FMGLLAVYTYFRARMRALKGHAGHPAA-

------------------------------------------------------------
--MGKRGRCFVVTMGPD--FGS--EALSRRLVLMLL-AALLMARADAARVRSVLYSPSDS
LVLLGQNTLR--P

PF00085 // ENSGT00390000008045_0_Domain_0 (134, 226)

TVL--GSPSSWVVEFFASWCGHC-------IAFAPK-----WKALAN
EVKDWRPVLNVAALDCADEVNSEICRDFGITAYPTVKFFKAFSNN

ENSGT00390000008045_0_Linker_0_2 (226, 525)

SST--GKEM---SVF
GKSVEDLQQMLIDGL---ESHHGGRWPPSCP-PLAPIRLEEINNFFLRNPDDYLALIFEK
KYSYVGREVELDLSQYHGIKVRRVLDVQEEIVKKFDVTTFPSCYLLTRNGSRSRVP-VLI
ESRSLYTTYLQRLPGVAKRTFTPT-VKPT------TGDRGAPPVRTFADRSKIYMSDLES
SLHYILRVEVGKF--KVLEGERLRALK-NFVSVLAKYYPGQPLGRNFLHSMDVWVPWQQR
KSIPYSSLEA-ALNNRRE--GAVLPKKLTWVGCQGSEPHFRGFP

PF04777 // ENSGT00390000008045_0_Domain_2 (525, 628)

CSLWILFHSLTVQAAQ
HNEY-LQQK-GDPQEILQAIRGYVKFFFGCRDCANHFEQMAAASMDQVKSMDEAILWFWN
RHNRVNARLAG-KASEDPRFPKIQ--WPPRDLCNPCHN-EVEG-APVWNLGAILAFLKSH
FSARNMVFNHSLSDKS-----------LQT---------EW----P--------------
---------------------------KYYRSSELNKSL-------DLIAGDMLLTLDD-
---GAMFLDPKPKVSRKLTKRDTLTLELEEG-----------------AE----------
------------------GKKVG-----DRAQPDGQWWWMLGGSFSYLDVSLCIGLYSLS
IMCLVGMCTYFQERMRSRKGRMSHCSA-

------------------------------------------------------------
----------MRMCGRS--CGPPPSLL------LLLLLLLLAVPGAGAAGVSALYSPSDP
LTL

PF00085 // ENSGT00390000008045_0_Domain_0 (124, 220)

LQADTVR--DVVL--DSRSAWAVEFFASWCGHC-------IAFAPT-----WRALAR
DIKDWRPALNLAALDCADENNSAVCRDFNIPGFPTVRFI

ENSGT00390000008045_0_Linker_0_2 (220, 525)

KLFVGEGS---STLFPPEPVS
GADVQMLRERLIDTL---ESHR-DTWPPACP-PLEPVKLAEIDGFFAKNSEEYLALIFEK
EDSYIGREVTLDLSQHQDIAVRRVLPTEDNVLKKFGVTSFPSCYLLFRNGSASRVP-VLM
ESRSFYTTYLQRLSGLTREAPQTT-AAPI------PATSIAPTVWKIADRSKIYMADLES
ALHYILRVEVGKF--SVLEGQRLVALK-NFVAVLAKXFPGQPLAQNFLHSLNEWLQRQQR
KKIPYSFLKT-VLDDRKE--GTVIAKKVNWIGCQGSEPHFRGFP

PF04777 // ENSGT00390000008045_0_Domain_2 (525, 628)

CSLWVLFHLLTVQAAR
QKV-DRPQDMAKAQEVLQAIRGYVRFFFGCRDCAAHFEQMAVDSMDRVGSLNDAVLWFWS
SHNRVNARLAG-APSEDPQFPKVQ--WPPIELCSACHN-ELHG-VPVWDVAATLRFLKAH
FSPSNIVLNAPPARLAPR----SSTQNVTAAPELLMEALKLKS-GNS-PLDPEEAEV-V-
---RFLGVTV-PDVLAEKPE--------ASHSMELHASPKPI--PAEPQRGPPEPVAGP-
---QGGE-VGQQQRLRHLSKRDSGAALLAKPWAEKNHPRGPLGLR-HIGHSSKQLA----
---------------DDPAGEL----EAQARRGRGQWLQVLGGSFSHLDISLLVGLYSLS
FMGLLAVYTYFRAKVRALKAHAGHPAA-

------------------------------------------------------------
--------SGLCICGAT---------------LV---LL-----ATVVPSHAGLYTPDE

PF00085 // ENSGT00390000008045_0_Domain_0 (120, 250)

P
VVHLDRKAHT---YLL--GSRSFWVAEFYASWCGHC-------QRFKPS-----WSGLAE
DIKDWRPVVYLGVIDCAESSNFETCNEFGVEGYPTIKSFKSFTKEVSQ--GVSE----DA
VHSVQALRE

ENSGT00390000008045_0_Linker_0_2 (250, 527)

NIITRL---EEQK-DSRPSSWP-PLEPISTFEVENFFKTKQENYLALIFEE
PSMYIGRETTLDMVQYEGVSVRRVLRDQNDMVNKFWITSYPSLVLLSRNGSNTVVN-LKA
DTRSSYTDFLRSLPGVRKKNLFIIGVANN--------GTTEQDDRRIADSTKLYMADLES
AVHYTLRAEVSRF--SHLEGERLDALI-AYVSVLRKYFPARPYGTTLLKSIHSWLHDRAG
KEVLYKDFEN-VLNNKDEAQNAVLSSSVNYVWCQGSHPNFRGFPCS

PF04777 // ENSGT00390000008045_0_Domain_2 (527, 628)

LWTLFHFLTVQASE
DTA-------APPTEVLLGLRGYVKNFFGCRECAGHFESMAAESMNTVNTLDEAILWLWD
RHNRVNKRLAG-QPSEDPEFPKLP--WPSKTLCPFCQV-EDGGDELAWDIPNVLNFMKTH
YSRQNLANDYLEDEEVLLERQKNGTKKEVTKPNEDISVEETSD-KT--------------
---ESHINLRYPQRNAEDHENKNVPL---------------TTQETNPDKNPTESEVQFA
AHLRVEDEKNTGE----------GNSFLLSLLP-SRSLQGSIELGSDHALQAKIIIDIPE
EEFDHIAVRKRLLRRGIDENFIGVVAEKGTVNVKGRLGKMLEVGFSRLDISLCVLLYFLS
SMCLLCMYLYMSLRTRCLRQRTFYP---

------------------------------------------------------------
--------------------MPRRPALP-----LVLLALLLAG---PRALDAGLYSPLDP
LAV

PF00085 // ENSGT00390000008045_0_Domain_0 (124, 226)

LGADSLE--RRLF--NSSSAWVMEFYASWCGHC-------IRFAPT-----WKQLAR
DIRDWRPAVMLGVLDCAERSNRKICTDFGVTGYPTLKFFKAFSKK

ENSGT00390000008045_0_Linker_0_2 (226, 525)

PED--GLKL---RRQ
GDDIKSLRESIITSL---EKHE-DMWPPSCP-PLEPISAAELHDFFQTNSVTYLALIFED
ENSFLGREVTLDMLQFENIAIRRVLQTNEELVKRFNVTSFPSGFLLVNNGSCSSIP-VNA
DFRPFYRSFLQSLPNVFRGNSFRPTVPPT------VEPKSTIVPWRVADRKKVYMADLES
AILYTLRVEAARF--RHLDKERLSVLK-QYVNLLVKYFPGRPAVMNYLRNLDLWLKPMTN
VSG--NEWEE-ALGNNPELPHARLPENTLWVGCQGSKPEFRGFP

PF04777 // ENSGT00390000008045_0_Domain_2 (525, 628)

CGLWTLFHLLTVQEAL
LSP-----YRSSPPEVLPAMRGYIKYFFGCRECAEHFEGMAAESMSRVKNKDGAILWLWS
RHNRVNYRLQG-APSDDPKFPKIQ--WPPQDLCWSCQI-IVNG-KRMWDERAILRFFKAH
FSRGNIYLDFIKPLIRRGRDVEEKDHNVVGKLEEGKEEENGRQVEEEFEED--KKRTEKP
ESGRVT-------RKLERSG-----LTEPHKPSIIKMS--TKTKELEEDIVDLDSFSELH
YKSKALKMAGQIGSRNRRSKRDVGLVRMENEGQQSFDIDAAWERLRHKSWGGQHLIG---
---------------AMEEEEEELEKENGVVSKRNQWFHILGVGFSQLDISLCIVLYFLS
SMCLLGMYAFFRVHMKYRKGRSGFRVA-

------------------------------------------------------------
----------MRRCNS-G-SGPPPSLL-------LLLLWLLAVPGANAAPRSALYSPSDP
LTLLQADTVR--G

PF00085 // ENSGT00390000008045_0_Domain_0 (134, 223)

AVL--GSRSAWAVEFFASWCGHC-------IAFAPT-----WKALAE
DVKAWRPALYLAALDCAEETNSAVCRDFNIPGFPTVRFFKAF

ENSGT00390000008045_0_Linker_0_2 (223, 525)

TKNGS---GAVF---PVA
GADVQTLRERLIDAL---ESHH-DTWPPACP-PLEPAKLEEIDGFFARNNEEYLALIFEK
GGSYLGREVALDLSQHKGVAVRRVLNTEANVVRKFGVTDFPSCYLLFRNGSVSRVP-VLM
ESRSFYTAYLQRLSGLTREAAQTT-VAPT------TANKIAPTVWKLADRSKIYMADLES
ALHYILRIEVGRF--PVLEGQRLVALK-KFVAVLAKYFPGRPLVQNFLHSVNEWLKRQKR
NKIPYSFFKT-ALDDRKE--GAVLAKKVNWIGCQGSEPHFRGFP

PF04777 // ENSGT00390000008045_0_Domain_2 (525, 628)

CSLWVLFHFLTVQAAR
QNV-DHSQEAAKAKEVLPAIRGYVHYFFGCRDCASHFEQMAAASMHRVGSPNAAVLWLWS
SHNRVNARLAG-APSEDPQFPKVQ--WPPRELCSACHN-ERLD-VPVWDVEATLNFLKAH
FSPSNIILDFPAAGSAAR----RDVQNVAAAPELAMGALELES-RNS-TLDPGKPEM-M-
---K-SPTNTTPHVPAEGPE--------ASRPPKLHPGLR-----AAPGQEPPEHMAEL-
---QR-NEQEQPLGQWHLSKRDTGAALLAESRAEKNRLWGPLEVR-RVGRSSKQLV----
---------------DIPEGQL----EARAGRGRGQWLQVLGGGFSYLDISLCVGLYSLS
FMGLLAMYTYFQAKIRALKGHAGHPAA-

------------------------------------------------------------
----------MGRCGR-G-SEPLPSLL----L---LLLLLLAVPGAGAAPRSALYSPSDP
LTLLQADTVR--G

PF00085 // ENSGT00390000008045_0_Domain_0 (134, 223)

AVL--GSRGAWAVEFFASWCGHC-------IAFAPT-----WKALAE
DVKAWRPALNLAALDCAEETNSAVCRDFNIPGFPTVRFFKAF

ENSGT00390000008045_0_Linker_0_2 (223, 525)

SKNGS---GAVF---PVA
GADVQTLRKRLIDAL---ESHH-DTWPPACP-PLEPAKLEEIDGFFARNKEEYLALIFEK
GGSYLGREVALDLSQHKGVAVRRVLNTEADVVRKFGVTDFPSCYLLFRNGSVSRVP-VLM
ESRSFYTAYLQRLSGLTREAAQTT-VAPT------TANKIAPTVWKFADRSKIYMADLES
ALHYILRIEVGRF--PVLEGQRLVALK-KFVAVLAKYFPGRPLVQNFLHSVNEWLKRQKR
NKIPYSFFKT-ALDDRKE--GAVLAKKVNWIGCQGSEPHFRGFP

PF04777 // ENSGT00390000008045_0_Domain_2 (525, 628)

CSLWVLFHFLTVQAAR
QNV-DHSQEAAKAQEVLPAIRGYVHYFFGCRDCAGHFEQMAAASMHRVGSPNAAVLWLWS
SHNRVNARLAG-APSEDPQFPKVQ--WPPRELCSACHN-ERLD-VPVWDVEATLHFLKAH
FSPSNVILDFPAAGSAAR----REAQSVAAAPEVAMGALELEG-RNS-TLDPGKPEM-M-
---K-SPANTTPDVPAERPE--------ASRPPKLRPGLG-----AAPGQEPPEHMAEL-
---QR-NEREQLRGQWHLSKRDTGAALLAESRAEKNHLWGPSEVR-RVGRSSKQLV----
---------------DIPEGQL----EARAGRGRGQWLQVLGGGFSHLDISLCVGLYSLS
FMGLLAMYTYFRAKIRALKGHAGHPAA-

------------------------------------------------------------
------------------------------------------------AQLSVLYSSSDP
LTLLQA

PF00085 // ENSGT00390000008045_0_Domain_0 (127, 224)

DTVR--AAVF--GSRSAWVVEFFASWCGHC-------IAFAPT-----WKALAN
DVKGWRPALNLAALDCADETNSAVCRDFNIPGFPTVRFFKAFS

ENSGT00390000008045_0_Linker_0_2 (224, 525)

KSGS---GTAL---PVA
GANVQTLRERLIDAL---ESHH-DTWPPACP-PLEPAKLEEIDGFFARNNEEYLALIFEK
EGSYVGREVALDLSQHRDIAVRRVLNTEANVVNKFGVTDFPSCYLLFRNGSVSRVP-VLV
ESRPFYTAYLQRLAGLPREAPATT-ATPA------TTEEIAPTVWKFADRSKIYMADLES
ALHYILRVEVGKF--SVLEGQRLLALK-KFVAVLAKYFPGQPMVQNFLHSISDWLKRQQR
RKIPYSFFKA-ALDNRKE--DSVLAEKVNWIGCQGSAPHFRGFP

PF04777 // ENSGT00390000008045_0_Domain_2 (525, 628)

CSLWVLFHFLTVQASR
YST-DHPQEPASGQEVLQAIRNYVRFFFGCRDCASHFEQMAAASMHRVGSPNDAVLWLWT
SHNKVNARLSG-APSEDPQFPKVQ--WPPRELCSSCHN-ELRG-VPVWDLGAILNFLKIH
FSPRNIVLDSPIAGPAPR----RGSQSLAASPKLLF------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----WRPALNLAALNCADETNNAVCRDFNIAGFPSVR-----------------------
------------------------------------------------------------
--------VTLDLSQHHDLVVRRVLSTEANVVRKFGVADFPSCYLLFRNGSVSRVP-VLV
ESRRFYTAYLQRLSEVTREGTPTP-AVPT------ISDQIAPTVWKFADRSKIYMADLES
ALHYILRVEVGRF--SVLEGQRLMALK-KFVTVLTK------------------------
--------------------EAVITKEVNWVGCQGSESHFRGFP

PF04777 // ENSGT00390000008045_0_Domain_2 (525, 628)

CSLWILFHFLTVQASQ
KNA-ESSQKPANGQEVLQAIRNYVRFFFGCRDCANHFEQMAAGSMHRVKSPNDAVLWLWT
SHNRVNARLAG-APSEDPQFPKVQ--WPPPELCSACHN-ELSG-EPVWDVDATLRFLKTH
FSPSNIVLNFPPAEPASR----SSVHSWGATPHLELDALGLVT-RNS-ALALERAEI-S-
---ESPGSNAMPNIPAERPE--------ASGPHMLHTGLQLS--R-LPGQVLPKHVA---
----------EPRGQQRLTKRDTGAVLLAESWAEQNHLQGLSELR-QGARSSKQLA----
---------------SILEREP----ESHAVWGQGQWLQVLGRDFSHLDISLCVGLYSLS
FMGLLAMCSYFRARMRVLKGHAGHLAA-

------------------------------------------------------------
----------MRRCGRH--SGPPSL----LLLLLLLPPLLLSVPGAYAARLSVLYSSSDP
LTLLDADTVR--P

PF00085 // ENSGT00390000008045_0_Domain_0 (134, 224)

AVL--GSSSAWAVEFFASWCGHC-------IAFAPT-----WKELAN
DVKDWRPALNLAVLDCADETNSAVCREFNIAGFPTVRFFKAFS

ENSGT00390000008045_0_Linker_0_2 (224, 525)

KNGT---GTAL---PAA
GANVQTLRMRLIDAL---ESHR-DTWPPACP-PLEPAKLKDINEFFTRSKAEYLALIFER
EDSYLGREVTLDLSQFHAVAVRRVLNSESDVVSKFAVTDFPSCYLLLRNGSVSRVP-VLV
ESRPFYTSYLRGLPGLTREAPPTT-AAPV------TPDKIAPTVWKFADRSKIYMADLES
ALHYILRVEVGKF--SVLEGQRLVALK-KFVAVLAKYFPGQPLVQNFLHSINDWLQKQQK
KKIPYSYFKA-ALDSRKE--NAVLAEKVNWIGCQGSEPHFRGFP

PF04777 // ENSGT00390000008045_0_Domain_2 (525, 628)

CSLWVLFHFLTVQAHR
YSE-AHPQEPADGQEVLQAMRSYVQSFFGCRDCANHFEQMAAASMHQVKSPSNAVLWLWT
SHNRVNARLSG-ALSEDPQFPKVQ--WPPRELCSACHN-EVNGQVPLWDLGATLNFLKAH
FSPANIVRDPPAPGPASR----RGTQDPEASPNLVMDTLKLET-GNS-VLGHEQAAS-A-
---ASPGATA-LDVPAGKPE--------ASGPQELNAGLSMG--GASPGQGPPEHTEEL-
---LR-DVQENAQGQQHLSKRDTEALLLPEV---N-HLQGPLAPR-RGGHSPKQLA----
---------------SILEGEP----EALAIQGRRQWLQVLGGGVSFLDISLCVGLYSVS
FMGLLAMYTYFRARMRTPKGHVSYPTA-

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---EWRPAVMLAALDCADEANQQVCAEFGITGFPTLKRGRAGGNPSSSFSGSSG---AAA
CRTVGARRLVMMARLSPALHSP-SMTPECCPAPDAPGSAEEVHSFFHRNTEQYLALIFEK
SNSFVGREVALDLLQYENVAVRRVLSSEEELVEKFGVTTFPSAYLLLRNGSFFRLP-VHA
EARSFYTYYLRALSGVTRGSYRLNVTSSA------INE-TRALQPVRADSSKLYVADLES
TVHYTLRVEAGRP--AVLAGAQLAALK-CYVATLAKYFPGRPSVQTFLHSLDSWLRNWTE
PELPRSTLKEAVKNKEDAIPAAVLPTNITWVGCRGSEPHFRGYPCG

PF04777 // ENSGT00390000008045_0_Domain_2 (527, 627)

LWTIFHLLTVQAAQ
GGP-----DQELPLEVLNTMRCYVKHFFGCQECAQHFEAMAAKSMDQVKSRDEAVLWLWS
HHNEVNARLAG-GDTEDPQFPKLQ--WPPPDMCPQCHR-EEQG-VHMWDEAAVLSFLKEH
FSLGNLRLD---------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------

------------------------------------------------------------
----------MKRCGRR--SGP-----PPQLLLLLLPPMLLAVPGAGAARLSALYSSSDP
LTLLQAD

PF00085 // ENSGT00390000008045_0_Domain_0 (128, 223)

TVR--GAVL--NSRSAWVVEFFASWCGHC-------IAFAPT-----WKALAN
DVKDWRPALNLAALDCADESNTAICRDFSISGFPTVRFFKAF

ENSGT00390000008045_0_Linker_0_2 (223, 525)

SKSGV---GTTL---PVA
GADVQTLRERLIDAL---ESHR-DTWPSACP-PLEPARLEEIEGFFARNNEEYLALIFEK
EGSYLGREVTLDLSQHQGMVVRRVLNTEGNVVSKFGVTDFPSCYLVFRNGSVSRVP-VLV
ESRSFYTAYLQRLSGLTRAAPQTT-AVPT------IADKVAPTVWKLADRSKVYMADLES
ALHYILRTEVGKF--SVLEGQRLVALK-KFVAVLAKYFPGQPLVQNFLHSVNDWLKRQQK
KKIPYSFFKA-ALDSRKE--DTVLAKKVNWVGCQGSEPHFRGFP

PF04777 // ENSGT00390000008045_0_Domain_2 (525, 628)

CSLWVLFHFLTVQASQ
QSI-DHSQEPAPGQEVLQAIRNYVRFFFGCRDCADHFEQMAAGSMHRVRSLDEAVLWLWS
GHNRVNARLAG-APSEDPQFPKVQ--WPPPELCSACHN-ELSG-EPVWDLGATLSFLKAH
FSLQNLVLDFPTAGPAPR----RGAQSLAATPKLGMGVLEMVT-RNS-TLGPEQAEP-K-
---ESPGAAV-PDVPAERPE--------ASGTPELP----AG--LA-VSTAAPEHMEEL-
---RG-GVPEQPQEQRHFNKRDTRELLA-GAWAEE-NHRGPAALR-QGGRGFKQLA----
---------------HVPEGEP----KALAVSGHGQWLQVLGGGFSHLDISLCVGLYSLS
FMGLLAVYTYFRARMRALKVHAGYSAA-

------------------------------------------------------------
----------MRRCGRCS-RAQPLSL-------SLLLLLLLWLPGAGAA-RSALYSESD

PF00085 // ENSGT00390000008045_0_Domain_0 (120, 183)

P
LTVLQASSLR--STVL--GSRSAWAVEFFASWCGHC-------IAFAPT-----WKALAN
DIKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---XXXX---XXX
XXXXXXXXXXXXXXX---XXXX-XXXXXXXX-XXXXXXMEEINGFF-RNNEEYLALIFEK
EGSYVGREVTLDLSQHQGIVVRRVLNTEAEAVSKFGVTDFPSCYLLFRNGSASRVP-VLV
ESRLFYTAYLQRFAGAPRETTQTTAVVPT------VPNTVVPTDWKVADRSKIYMADLES
ALHYILRVEVGKF--SILEGQRLVALK-NFMKVLAQYFPGQPLVQNFLHSTYDWLMKQHK
EKIPYELFKT-VLDKRKE------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------

------------------------------------------------------------
----------MWRCGRH--SGPPSL----LL--LLLPPLLLSGPGAYAARLSVLYSSSDP
LTLLDADTVR--P

PF00085 // ENSGT00390000008045_0_Domain_0 (134, 222)

TVL--GSSSAWAVEFFASWCGHC-------IAFAPT-----WKELAN
DVKDWRPALNLAVLDCAEETNSAVCREFDIAGFPTVRFFQA

ENSGT00390000008045_0_Linker_0_2 (222, 525)

FTKNGS---GATL---PGA
GANVQTLRMRLIDAL---ESHR-DTWPPACP-PLEPAKLKDIDEFFTRNKAEYLALVFER
EDSYLGREVTLDLSQYHAVAVRRVLNTESDVVSKFGVTDFPSCYLLLRNGSVSRVP-VLV
ESRSFYTSYLRGLPGLTRDAPPTT-ATPV------TADKIAPTVWKFADRSKIYMADLES
ALHYILRVEVGKF--SVLEGQRLVALK-KFVAVLAKYFPGQPLVQNFLHSINNWLQKQQK
KKIPYSFFKA-ALDSRKE--DAVLTEKVNWVGCQGSEPHFRGFP

PF04777 // ENSGT00390000008045_0_Domain_2 (525, 628)

CSLWVLFHFLTVQANR
YSE-AHPQEPADGQEVLQAMRSYVKFFFGCRDCANHFEQMAAASMHQVRSPSNAVLWLWT
SHNRVNARLSG-ALSEDPHFPKVQ--WPPRELCAACHN-ELNGQVPLWDLGATLNFLKAH
FSPANIVIDSSASRHTAR----RG--SPEAAPELVMDTLKLES-RNS-VLGHEQAAS-A-
---ESPGATA-LDVPAEKPE--------ASGPQELYTGLRMG--GASPGQGPPESVEEH-
---QR-DVQENAQGQQHLSKRDTEALLLPEV---N-HLQGPLELR-RGGRSPKQLA----
---------------PILEGEP----EAPAIQGQGQWLQVLGGGISHLDISLCVGLYSVS
FMGLLAMYTYFRARLRTQKGHASYPTA-

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----WRPALNLAVLDCADEANTAVCRDFDILGFPTVRFFKAFSKSGP---GTAL---PVA
GANVETLRRRLIDAL---ESHN-DTWPSACP-PLKPVKMKEINKFFTRNNTEYLALIFEN
KDSYLGREVALDLSQRR-IPVRRVLNTEKDVVNKFGVTDFPSCYLLFRNGSASRVP-VLM
ESRSFYTSYLRGLSGPTRETPSTT-AAPV------TTENIVPTVWNIVDHSKIYMADLES
SLHYILHVEVGKF--SVLDGHRLAALK-KFMAVLAKYFPGRPSVQNFLYSLNDWLYKQQR
KKMPYSFFRA-AMDDRKK--DSVLDEKVNWVGCQGSEPHFRGFP

PF04777 // ENSGT00390000008045_0_Domain_2 (525, 628)

CSLWVLFHFLTVQASR
YSE-NYPQEPADGQEVLQAMRNYVRFFFGCRDCANHFEQMAAASMHRVTNPRSAVLWLWT
SHNRVNARLSG-APSEDPLFPKVQ--WPPRDLCFACHN-ELSGQQPVWDVDATFNFLKAH
FSPGNIIMESPAAGLTTQ----RGPQKPETTAELVMDALELET-RNS-VLGHEQAAS---
---TKSPGATALDVPAETPE--------ASGPRELYTGLRMS--GAPAGQGPPEHMEEL-
---QR-DTQEHAQGQRHLSKRHTEVLLLPG----VNHLQGPLELR-RGGRSPKQLA----
---------------SMPEGEP----EARAVPGQGLWLQVLGGGFSHLDLSLCVGLYSVS
FMGLLAM--YFRARMRTLKGHASHPVA-

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---EWRPAVILGAIDCADEDNQQVCSDFGITGFPTMKFFRAFSKKPED--GIRI---TNP
SATVEDLRHAIITNL---EQSQ-DAWPPACP-PLEPASAEEVRTFFQRNKDRYLALIFEK
SNSFVGREVALDMLQYENIAVRRVLSSEEELVEKFGVTSFPSGYLLFRNGSFSRLP-VHI
EARSFYTYYLRTLTGITRGSYKLNATASS------ANETDRVPHPLRADRSKLYMADLES
ALHYSLRVEAARA--SSLSGAQLAAFK-CYVATLVKYFPGRPCVQTYLQTLDAWLRNWTE
PELPRTVLKEAMKNNRDASHPSVLPTNVTWVGCQGSERHFRGYP

PF04777 // ENSGT00390000008045_0_Domain_2 (525, 628)

CGLWTIFHLLTVQAAQ
NGP-----DKELPLEVLSTMRCYVRHFFGCQECAEHFEAMAAKSMDRVASREEAVLWLWS
HHNEVNARLAG-GDTEDPKFPKLQ--WPPPDLCPQCHK-EERG-VHAWEEPAVVTFLKAH
FSPANIYMDYAEPDPIPVAREGA-GARLGTEGPREER-GRGEEEEK---ET--EGEA--R
IPGRPG-------GGGGGGG-----SPEPRRPSIVRLN--PKVREGGEDIVDLDSFSEQH
FRSQALRAAA--GRRRRISKRDTVALARG--------DAGGE-RRRGP--------G---
---------------IL----LREEEEGGESLRRSPWLRVLGLGFSRLDISLCVALYFLS
SMCLLGMYTFFRLRTRARKGRPGFPLA-

------------------------------------------------------------
----------MGRCGR-G-SGPLPSLL----L---LLLLLLAVPGAGAAPLSALYSPSDP
LTLLQADTVR--G

PF00085 // ENSGT00390000008045_0_Domain_0 (134, 223)

AVL--GSRGAWAVEFFASWCGHC-------IAFAPT-----WKALAE
DVKAWRPALNLAALDCAEETNSAVCRDFNIPGFPTVRFFKAF

ENSGT00390000008045_0_Linker_0_2 (223, 525)

SKNGS---GAVF---PVA
GADVQTLRERLIDAL---ESHH-DTWPPACP-PLEPAKLEEIDGFFARNKEEYLALIFEK
GGSYLGREVALDLSQHKGVVVRRVLNTEADVVRKFGVTDFPSCYLLFRNGSVSRVP-VLM
ESRSFYTAHLQRLSGLTREAAQTT-VAPT------TANKIAPTVWKIADRSKIYMADLES
ALHYILRIEVGRF--PVLEGQRLVALK-KFVAVLAKYFPGRPLVQNFLHSVNEWLKRQKR
NKIPYSFFKT-ALDDRKE--GAVLAKKVNWIGCQGSEPHFRGFP

PF04777 // ENSGT00390000008045_0_Domain_2 (525, 628)

CSLWVLFHFLTVQAAR
QNV-DHSQEAAKAQEVLPAIRGYVHYFFGCRDCAGHFEQMAAASMHRVGSPNAAVLWLWS
SHNRVNARLAG-APSEDPQFPKVQ--WPPRELCSACHN-ERLD-VPVWDVEATLNFLKAH
FSPSNIILDFPAAGSAAR----RDAQNVAAAPELAVGALELEG-RNS-TLDPGKPEM-M-
---K-SPANTTPDVPAERPE--------ASRPPKLRPGLG-----AAPGQEPPEHMAEL-
---QR-NEQEQPRGQWHLSKRDIGAALLAESRAEKNRLWGPSEVR-RVGRSSKQLV----
---------------DIPEGQL----EARAGRGRGQWLQVLGGGFSHLDISLCVGLYSLS
FMGLLAMYTYFRAKIRALKGHAGHPAA-

MTPDQAPLFSHLIHNVSSLCGSPGTALQQPKSGSSIPTDSSSVGYGGRERPNNLREATPA
ATARRALHSFTGLCNR-G-SGPPPSLL-------LLLLWLLAVPGANAAPRSALYSPSDP
LTLLQADTVR--G

PF00085 // ENSGT00390000008045_0_Domain_0 (134, 223)

AVL--GSRSAWAVEFFASWCGHC-------IAFAPT-----WKALAE
DVKAWRPALYLAALDCAEETNSAVCRDFNIPGFPTVRFFKAF

ENSGT00390000008045_0_Linker_0_2 (223, 525)

TKNGS---GAVF---PVA
GADVQTLRERLIDAL---ESHH-DTWPPACP-PLEPAKLEEIDGFFARNNEEYLALIFEK
GGSYLGREVALDLSQHKGVAVRRVLNTEANVVRKFGVTDFPSCYLLFRNGSVSRVP-VLM
ESRSFYTAYLQRLSGLTREAAQTT-VAPT------TANKIAPTVWKFADRSKIYMADLES
ALHYILRIEVGRF--PVLEGQRLVALK-KFVAVLAKYFPGRPLVQNFLHSVNEWLKRQKR
NKIPYSFFKT-ALDDRKE--GAVLAKKVNWIGCQGSEPHFRGFP

PF04777 // ENSGT00390000008045_0_Domain_2 (525, 628)

CSLWVLFHFLTVQAAR
QNV-DHSQEAAKAKEVLPAIRGYVHYFFGCRDCASHFEQMAAASMHRVGSPNAAVLWLWS
SHNRVNARLAG-APSEDPQFPKVQ--WPPRELCSACHN-ERLD-VPVWDVEATLNFLKAH
FSPSNIILDFPAAGSAAR----RDVQNVAAAPELAMGALELES-RNS-TLDPGKPEM-M-
---K-SPTNTTPDVPAEGPE--------ASRPPKLRPGLG-----AAPGQEPPEHMAEL-
---QR-NEQEQPLGQWHLSKRDTGAALLAESRAEKNRLWGPLEVR-RVGRSSKQLV----
---------------DIPEGQL----EARAGRGRGQWLQVLGGGFSYLDISLCVGLYSLS
FMGLLAMYTYFQAKIRALKGHAGHPAA-

------------------------------------------------------------
----------MRRCGRL--SGPPSL----LLLLLLLSPLLFSGPGAYAARLSVLYSSSDP
LTLLDADSVR--PT

PF00085 // ENSGT00390000008045_0_Domain_0 (135, 222)

VL--GSSSAWAVEFFASWCGHC-------IAFAPT-----WKELAN
DVKDWRPALNLAVLDCAEETNSAVCREFNIAGFPTVRFFQA

ENSGT00390000008045_0_Linker_0_2 (222, 525)

FTKNGS---GATL---PGA
GANVQTLRMRLIDAL---ESHR-DTWPPACP-PLEPAKLNDIDEFFTRNKADYLALVFER
EDSYLGREVTLDLSQYHAVAVRRVLNTESDLVSKFGVTDFPSCYLLLRNGSVSRVP-VLV
ESRSFYTSYLRGLPGLTRDAPPTT-ATPV------TADKIAPTVWKFADRSKIYMADLES
ALHYILRVEVGKF--SVLEGQRLVALK-KFVAVLAKYFPGQPLVQNFLHSINDWLQKQQK
KRIPYSFFKA-ALDSRKE--DAVLTEKVNWVGCQGSEPHFRGFP

PF04777 // ENSGT00390000008045_0_Domain_2 (525, 628)

CSLWVLFHFLTVQANR
YSE-AHPQEPADGQEVLQAMRSYVQFFFGCRDCANHFEQMAAASMHQVRSPSNAILWLWT
SHNRVNARLSG-ALSEDPHFPKVQ--WPPRELCSACHN-ELNGQVPLWDLGATLNFLKAH
FSPANIVIDSSASRHTGW----RG--RPEATPELVMDTLKLES-RNS-VSGHEQAAS-A-
---ESPGATA-LDVPTEKPE--------ASGPQELYTGLRMG--GASPGQGPPEHMEEH-
---QR-DMQENAPGQQHLSKRDTEALLLPEV---N-HLQGPLELR-RGGRSPKQLA----
---------------PILEEEP----EALAIQGQGQWLQVLGGGISHLDISLCVGLYSVS
FMGLLAMYTYFRARLRTPKGHASYPTA-

------------------------------------------------------------
----------MERCGRG--SRPPPTLL----L------LLLAVPGAVAAPRSALYSPSDP
LTLLQADTVR--G

PF00085 // ENSGT00390000008045_0_Domain_0 (134, 221)

AVL--GSRSAWAVEFFASWCGH-----C--IAFAPT-----WKALAE
DVKAWRPALNLAALDCAEETNSAVCRDFNIPGFPTVRFFK

ENSGT00390000008045_0_Linker_0_2 (221, 525)

AFSRNGS---GAVF---PVA
GADVQTLRERLIDAL---ESHH-DTWPPACP-PLQPARLKEIDGFFARNNEEYLALIFEK
GGSYLGREVALDLSQHKGVAVRRVLNTEADVVRKFGVTNFPSCYLLFRNGSVSRVP-VLM
ESRSFYTAYLQRLSGLIREAPQTT-VAPT------TVNKIAPTVWKFADRSKIYMADLES
ALHYILRIEVGRF--SVLEGQRLVALK-KFVAVLAKYFPGQPSVQNFLHSVNEWLKRQKR
RKIPYSFFKT-ALDDRKE--GAVLAKKVNWIGCQGSEPHFRGFP

PF04777 // ENSGT00390000008045_0_Domain_2 (525, 628)

CSLWVLFHFLTVQAAR
QHV-DHPQEAAKAQEVLQAIRGYVRFFFGCRDCAGHFEQMAAASMDQVGSPDAAVLWLWS
SHNKVNARLAG-APSEDPHFPKVQ--WPPRELCSACHN-ERLD-VPVWDVEATLTFLKAH
FSPSNIVLGSPAAGSAPR----WDAQRVAAAPKLAMEGLELES-RNS-TLDPEKPEM-M-
---T-PPANTTPDVPAERPK--------ASHPPKLRPGLG-----AAPGRGPPEHMAEL-
---QR-NEREQPRGQWHLNKRDTGAVLLAESRAEKNRLWGPLEVR-HVGRGSKQLV----
---------------DIPEGQL----EARARQGRGQWLQVLGGGFSHLDISLCVGLYSLS
FMGLLAMYTYFRAKIRALKGHAGHPVA-

------------------------------------------------------------
---------------------------------LLLLLLLLAVARGDAARARRSTRPSKP
LTLLRAD

PF00085 // ENSGT00390000008045_0_Domain_0 (128, 225)

TLR--GAVL--GSRSAWAVEFFASWCEHC-------IAFAPT-----WKALAD
DVKAWRPALNLAALDCADEANTAVCRDFNIPGFPTVRFFKAFSK

ENSGT00390000008045_0_Linker_0_2 (225, 525)

SGS---GATL---SVA
GADVQALRERLIDAL---ESHS-DTWPTACP-PLEPARLKEINGFFARNNEEYLALIFEK
EGSYLGREVTLDLSQHRGITVRRVLNTEGDVVSKFGVTDFPSCYLLFRNGSVSRVP-VLV
ESRSFYTAYLQKFSGATRVAAQTS-VAPT------TAHTIAPTVWKVADRSKIYMADLES
ALHYILRVEVGKF--SMLEGHRLVALR-KFMAVLAQYFPGQPLTQNFLHSMNDWLKRQQK
KKIPYNLFKN-ALDNRKE--GAMIAKKVNWVGCQGSEPHFRGFP

PF04777 // ENSGT00390000008045_0_Domain_2 (525, 615)

CSLWILFHFLTVQAAR
QNV-DRSQETAKAQEVLQAIRSYVRFFFGCRECAGHFERMAAASMNRVKNPNSAVLWFWS
SHNKVNARLAG-KEGPPPRLDASQHTEPFHMLCQPCRCVSCLG-LRLWLGHACLGSLQAG
EGPGNIVLDLPSAVPGPR----RGARRMAATPKPGE--LELA--DRNFTLGP-EKAEIMV
GPGTKSPGTLIPDVPVERLG--------ESRPQEMHTGLGVT--TAGPDQGPPERTAEL-
---QR-DKLKQPKGQQHLTKRDTGAELLAEFLAEKPLPRGPSELR-RVGRSSKQLA----
---------------SVPEGEP----EAGAVRGRGQWLQVLERDFSHLDISLCVVLYSLS
FMGLLAVYTYFRARMRALKGHASHLAA-

------------------------------------------------------------
----------MGRCGR-G-SGPLPSLL----L---LLLLLLAVPGAGAAPRSALYSPSDP
LTLLQADTVR--G

PF00085 // ENSGT00390000008045_0_Domain_0 (134, 223)

AVL--GSRSAWAVEFFASWCGHC-------IAFAPT-----WKALAE
DVKAWRPALNLAALDCAEETNSAVCRDFNIPGFPTVRFFKAF

ENSGT00390000008045_0_Linker_0_2 (223, 525)

SKNGS---GAVF---PVA
GADVQTLRERLIDAL---ESHH-DTWPPACP-PLEPAKLEEIDGFFARNKEEYLALIFEK
GGSYLGREVALDLSQHKGVVVRRVLNTEADVVRKFGVTDFPSCYLLFRNGSVSRVP-VLM
ESRSFYTAYLQRLSGLTREAAQTT-VAPT------TANKIAPTVWKFADRSKIYMADLES
ALHYILRIEVGRF--PVLEGQRLVALK-KFVAVLAKYFPGRPLVQNFLHSVNEWLKRQKR
NKIPYSFFKT-ALDDRKE--GAVLAKKVNWIGCQGSEPHFRGFP

PF04777 // ENSGT00390000008045_0_Domain_2 (525, 628)

CSLWVLFHFLTVQAAR
QNV-DHSQEAAKAQEVLPAIRGYVHYFFGCRDCASHFEQMAAASMHRVRSPNAAVLWLWS
SHNRVNARLAG-APSEDPQFPKVQ--WPPRELCSACHN-ERLD-VPVWDVEATLNFLKAH
FSPSNIILDFPAAGSAAR----RDAQNMAAAPELAMGALELEG-RNS-TLDPGKPEM-M-
---K-SPANTTPDVPAERPE--------ASRPPKLRPGLG-----AAPGQEPPEHMAEL-
---QR-NEREQPRGQWHLRKRDTGAALLAESRAEKNRLWGPSEVR-RVGRSSKQLV----
---------------DIPEGQL----EARAGRGRGQWLQVLGGGFSHLDISLCVGLYSLS
FMGLLAMYTYFRAKIRALKGHAGHPAA-

------------------------------------------------------------
----------MERCGRG--SRPPPTLL----LL---L-LLLAVPGAVAAPRSALYSPSDP
LTLLQADTVR--G

PF00085 // ENSGT00390000008045_0_Domain_0 (134, 223)

AVL--GSRSAWAVEFFASWCGH-----C--IAFAPT-----WKALAE
DVKAWRPALNLAALDCAEETNSAVCRDFNIPGFPTVRFFKAF

ENSGT00390000008045_0_Linker_0_2 (223, 525)

SKNGS---GAVF---PVA
GADVQTLRERLIDAL---ESHH-DTWPPACP-PLQPAKMKEIDGFFARNNEEYLALIFEK
GGSYLGREVALDLSQHKGVAVRRVLNTEADVVRKFGVTNFPSCYLLFRNGSVSRVP-VLM
ESRSFYTAYLQRLSGLTREVPQTT-VAPT------TVNKIAPTVWKFADRSKIYMADLES
ALHYILRIEVGRF--SVLEGQRLVALK-KFVAVLAKYFPGQPLVQNFLHSVNEWLKRQKR
RKIPYSFFKT-ALDDRKE--GAVLAKKVNWIGCQGSEPHFRGFP

PF04777 // ENSGT00390000008045_0_Domain_2 (525, 628)

CSLWVLFHFLTVQAAR
QPV-DHSQEAAKAQEVLQAIRGYVRFFFGCRDCAGHFEQMAAASMDQVGSPDAAALWLWS
SHNKVNARLAG-AASEDPQFPKVQ--WPPRELCSACHN-ERLD-VPVWDVEATLTFLKVH
FSPSNIVLGFPAAGSAPR----WDAWRVAAAPKLAMEGLELES-RNS-TLDPEKPEM-M-
---T-PTANTTPDVPAERPE--------ASHPLKLRPGLG-----AGPGQGPPEHMAEL-
---QR-NEREQPHGQWHLNKRDTGAALLAESWAEKNRLWGPLEVR-HVGRSSKQLV----
---------------DIPEGQL----EARARQGRGQWLQVLGGGFSHLDISLCVGLYSLS
FMGLLAMYTYFRAKIRALKGHAGHPVA-

------------------------------------------------------------
----------MRGCGRR--SGP-----PSWLLLLLLPPLWLTVPGAGAAQLSVLYSSSDP
LTLLEAD

PF00085 // ENSGT00390000008045_0_Domain_0 (128, 223)

TVR--RAVL--GSRSAWAVEFFASWCGHC-------IAFAPT-----WKALAN
DVKEWSPALNLAALDCADETNSAVCRDFNIPGFPTVRFFKAF

ENSGT00390000008045_0_Linker_0_2 (223, 525)

SKNGS---GAVL---PVA
GANVQILRERLIDAL---ESHR-DTWPPACP-PLEPAKMKEIDEFFARNNKEYLALIFEK
EGSYLGREVTLDLSQHQGIVVRRVLNTEDDVVRKFGVTDFPSCYLLFRNGSVSRVP-VLV
ESRPFYTAYLQRLSGLTREAPPTT-AAPA------TADKIAPTVWKFADRSKIYMADLES
ALHYILRVEVGKF--SVLEGQRLVALK-KFVAILAKYFPGQPLVQNFLHSTNDWLKRQQR
RKIPYSFFKA-ALDSRKE--DSVLPERVNWIGCQGSEPHFRGFP

PF04777 // ENSGT00390000008045_0_Domain_2 (525, 628)

CSLWVLFHFLTVQASQ
HSE-NHPQELASGQEVLQAIRNYVRFFFGCRDCAGHFEQMAAASMHRVRSPNDAVLWLWT
SHNRVNARLSG-APSEDPQFPKVQ--WPPRELCSTCHN-ELRG-VPVWDLGAILGFLKGH
FSPTNIILGFPAAGPAPQ----KGTRSLTATSELLM------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------

------------------------------------------------------------
----------MECCGRG--SGP-----QP-SLLLLLLSLLLVVSGAGAAPRSALYSPSD

PF00085 // ENSGT00390000008045_0_Domain_0 (120, 245)

P
LTLLQAGTLR--DAVL--DSQSAWAVEFFASWCGHC-------IAFAPT-----WKALAK
DVKGWRPALNLAALDCAQETNTAVCRDFDIPGFPTVRFFKASSKTGS---GATL---SVA
GADV

ENSGT00390000008045_0_Linker_0_2 (245, 527)

QMLRERLIDAL---ESHN-DTWPSACP-PLEPARLKEITGFFARNDEDYLALIFER
EGSYLGREVTLDLSQRRGVVVRRVLNTQHDVVNEFGVTSFPSCYLLFRNGSSLRIP-VLM
ESRFFYTMYLKRFSRDTSETVPTP-TAPN------TSRPIAPTVWKVADPSKIYMADLES
ALYYILQVEVSKF--SVLEGQRLVALK-KFMAVLAQYFPGQPSVQKFLHSMSDWLKKQQR
KKIPYGFFKT-AXXXXXX--GALTADKVNWVGCQGSQPHFRGFPCS

PF04777 // ENSGT00390000008045_0_Domain_2 (527, 627)

LWVVFHFLTTEAAR
QDV-DHSRETVKAQEILQAIRGYVRFFFGCRACAGHFEQMATESVHQVGNLSSSILWFWS
SHNKVNARLAG-APSEDPEFPKVQ--WPPRELCSACHT-ELQG-APVWDLGNTLKFLKTH
FSPSNIVLDLPSAGLGPR----RGA-RMAVPPRQVE--LELA--IGNFTLGP-EKAEIMA
GPGTMSPGTTIPDVPAEGPG--------ASHPQEMQAGLSMA--RDEPDQEAPEHIAGL-
---QR-DKLEQPKGRQRLSRRDTGAVFLAEFLAGKNFPRGPSELR-RVGRSSKQLA----
---------------SDPDGEP----EAGARQDRSQWLQVLEGNFSHLDISLCVGLSSVS
FMGLLAVYTYFRARMRALKGYASHPAAR

------------------------------------------------------------
----------MRRCGRH--SGSPSQML----LLLLPPLLLLAVPGAGAAQLSVLYSSADP
LTLLDANT

PF00085 // ENSGT00390000008045_0_Domain_0 (129, 225)

VR--SAVL--GSSSAWVVEFFASWCGHC-------IAFAPM-----WKELAN
DVQDWRPAINLAVLDCADEVNTAVCRDFNIDGFPTVRFFKAYSKHSF---GTTL---PVA
GANLQTLRRRLIDAL---ESHN-DTWPSACP-SLKPAKLKEINKFFAKNKAEFLALIFED
KDSYVGREVILDLSQRH-VPVRRVLNTESDVVYKFDVTEFPSCYLLFRNGSISRIP-VLM
ESRPFYTSYLLGLSGPIREDPLST-AVPV------TT-DVVPTVWKTASVSKIYMADLES
SLHYIFRVEVGKF--SVLEGPRLQALK-KFMAILAKYFPGKPLAKNFLHSINDWLHRQPR
KTIPYSFFRA-ALDNRNE--GSILTEKVNWVGCQGSKPQYRGFPCSLWVLFHLLTVQASQ
YSE-DHPQDP--------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------

------------------------------------------------------------
----------MGRRGRS--SGPPLP-------RLLLLLMAAAGAGAGAVRRSVLYSPSD

PF00085 // ENSGT00390000008045_0_Domain_0 (120, 183)

P
LTLLQADTLR--GAVL--GSRSAWAVEFFASWCGHC-------IAFAPT-----WKALAN
DIKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXFFKAFTKNGS---GTHL---PVV
GADVQTLRERLIDAL---ETHR-DTWPPACP-PLEPARLEEINGFFARNNEEYLALIFEK
EGSYLGREVTLDLTQYRGVAVRRVLSTEEDVVSTFGVTDFPSCYLLFRNGSVTRVP-VLM
ESRSFYTAYLQRLSGVTREATQTT-TAPT------TANEIAPTVWKVADHSKIYMADLES
ALHYILRVEVGKF--SVLEGQRLVALK-KFVAVLAKYFPGQPLARNFLRSTSEWLWRQQR
NEIPYSSFKT-ALDNRKE--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXX-XXXXXXXK

PF04777 // ENSGT00390000008045_0_Domain_2 (553, 628)

PQEALQAIRGYVRYFFGCRDCAQHFEKMAAASMHRVDSLDGAVLWLWT
SHNKVNARLAG-APSEDPQFPKVP--WPTRELCTACHN-ELQG-DPVWDLGATLSFLKAH
FSPRNMVLGLPRAEPGLR----AAGARRAGTPELEMG--------NA-TLGPREPGMEA-
---PRLTVLDVPDVPAEQPG--------AGLAHAPGPDLGMI--SAAPDQGPPAPTVEL-
---PG-DEPEELEGQRHLSKRDTRALLLPDLPAELDPPRGPSGLRHHVGRRSKQLA----
---------------SIPDGEP----EPRGGRGRGQWLQVLEGGFSHLDISLCVGLYSLS
FLGLLAVYIYFRARMRALKGRTGHSAA-

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------PIEVVVLEEINSFFTKNRDQFLALIFEK
KGSFVGREVTLDLSQYEGIAVRRVLDTETVVIHKYRVTSFPSCYLLSRNSSISRVP-VLM
ETRSFYTAYLQRLPGVTKGPYRPT-VSPA------SQETTTPIVWRSADSSKVYMADLES
SLHYILRLEVGKY--PVLTGERLEALK-SFVAVLAKYFPGRPLVQNFLQELNKWLKDQRR
QKILYSTFEA-VLTRRKE--GNVLTNKVTWVGCQGSKPQFRGFP

PF04777 // ENSGT00390000008045_0_Domain_2 (525, 628)

CSLWILFHFLTVQAAQ
HTKYSLPNTQADPQEVLSAIRGYVRFFFGCRDCAAHFEEMAAASMDRVKSQDEAILWLWS
RHNQVNSRLAG-APSEDPRFPKIQ--WPPRSLCAPCHN-ELRG-EPVWDLGAILNFFKAH
FSPGNIASDYAQPLPARG----RR--HSVGERERKEMEEDLTT-ATQ-AWSPSHT-----
---EKPEGTF------QTEE--------GREPVMERSVLGTERRGSHQPQRPRIIRMST-
---KAQEEEEQLPQGRRLSKRDTVPLLLLKYAAALKR------LK-QQGQGAKQLA----
---------------SILEGKEGV-----KAPLGGLWLRLLGGDFSLLDISLCIGLYFLS
SMCLLGMYAYFRLRMRVRKGRASYPLS-

------------------------------------------------------------
----------MWRCGRH--SGSPSQ-----LLLLLLPPLLLALSGAGAAQLSVLYSSSDQ
LTLLDAN

PF00085 // ENSGT00390000008045_0_Domain_0 (128, 225)

TVR--QTVL--GSSSAWAVEFFASWCGHC-------IAFAPT-----WRELAN
DVRDWRPALNLAVLDCADETNNDVCRDFNIAGFPTVRFFKAFSK

ENSGT00390000008045_0_Linker_0_2 (225, 552)

NSS---GTTL---PVA
GANVHTLRRRLIDAL---ESHR-DKWPSACP-PLHPAKMKEIKEFFAKNNTEYLALIFED
KNSYVGREVTLDLSQRR-VPVRRVLNTESDVVSKFDVTDFPSCYLLFRNGSISRVP-VLM
ESRPFYTSYLRGLSGPTREAPPTT-AAPV------SAENIAPTVWKLADHSKIYMADLES
SLHYILRVEVGKF--SVLEGHRLMALK-KFVAVLAKYFPGRPLVQNFLHSINDWLHKQPR
KKIPYSFFRT----------DAVLVEKVNWVGCQGSEPHFRGFPCSLWGLCVVS------
------LFPPA

PF04777 // ENSGT00390000008045_0_Domain_2 (552, 628)

DGQEVLQAMRNYVRFFFGCRDCADHFEQMAAASLHRVTSPRNAVLWLWT
SHNRVNARLSG-APSEDPYFPKLQ--WPPRELCLACHN-ELNGQEPVWDLDATFNFLKAH
FSPVNIVMDSPAAGPAAQ----RGPQNHEATPELVMDAVELES-RNS-VLGHERAAS---
---AEPPGATALAVRAEKPE--------ASGPRELYTGLRMS--GAPAGQGPPEHVEEL-
---QR-DTQEHAQGWQHLSKRDTGVLLLPE----VNHL-----LR-RGSRSPKQLA----
---------------SIPEGEP----EARAIQGQGPWLQVLGGGFSHLDISLCVGLYSVS
FMGLLAMYTYFRARMRTLKGHASHHIA-

------------------------------------------------------------
----------MRRCGRL--SGPPSL----LLLLLLLSPLLFSGSGAYAARLSVLYSSSDP
LTLLDADSVR--PT

PF00085 // ENSGT00390000008045_0_Domain_0 (135, 222)

VL--GSSSAWAVEFFASWCGHC-------IAFAPT-----WKELAN
DVKDWRPALNLAVLDCAEESNSAVCREFDIAGFPTVRFFQA

ENSGT00390000008045_0_Linker_0_2 (222, 525)

FTKNGS---GATL---PGA
GANVQTLRMRLIDAL---ESHR-DTWPPACP-PLEPAKLKDIDEFFTRNKADYLALVFER
EDSYLGREVTLDLSQYHAVAVRRVLNTESDLVSKFGVTDFPSCYLLLRNGSVSRVP-VLV
ESRSFYTSYLQGLPGLTRDAPPTT-ATPV------TADKIAPTVWKFVDRSKIYMADLES
ALHYILRVEVGKF--SVLEGQRLVALK-KFVAVLAKYFPGQPLVQNFLHSINDWLQRQPK
KKVPYSFFKA-ALDSRKE--DAVLTEKVNWVGCQGSEPHFRGFP

PF04777 // ENSGT00390000008045_0_Domain_2 (525, 628)

CSLWVLFHFLTVQANR
YSE-AHPQEPADGQEVLQAMRSYVQFFFGCRDCANHFEQMAAASMHQVRSPSNAILWLWT
SHNRVNARLSG-ALSEDPHFPKVQ--WPPRELCSACHN-ELNGQVPLWDLGATLNFLKAH
FSPANIVIDSSASRHAGR----KG--SPEATSELVMDTLKLES-RNS-VSGHEQAAS-A-
---ESPGATA-LDVPAEKPE--------ASGPQELYTGLRMG--GASPGQGPPEHVEEH-
---QR-DMQENAPGQQHLSKRDTEALLLPEV---N-HLQGPLELR-RGGRSPKQLA----
---------------PILEGEP----EALAIQGQDQWLQVLGGGVSHLDISLCVGLYSVS
FMGLLAMYTYFRARLRTPKGHASYPTA-

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------QFFKAFSKNGS---GSAL---PVA
GADVETLRKRLIDAL---ESHS-DTWPPACP-PLEPARLKEIDGFFARNDKDFLALIFEK
EGSYLGREVTLDLSQHQGIAVRRVLNTEGDVVSKFGVTDFPSCYLLFRNGSASRVH-VLA
ESRSFYTTYLKRFSRPPREPVPTK-VVPT------TAHTIAPTVWKVADRSKIYMADLES
ALHYILRVEVGKF--SVLEGQRLVALK-KFVAVLAQHFPGQPLVQNFLHSINDWLKRQQR
KKIPYGFFKA-ALDNRKE--GTVIAEKVNWVGCQGSEPHFRGFP

PF04777 // ENSGT00390000008045_0_Domain_2 (525, 628)

CSLWILFHFLTVQAAR
HNF-DHSQETAKAQEVLQAIRSYVRFFFGCRDCANHFEQMAAASMHRVESLNSAVLWLWS
SHNKVNNRLAG-AASEDPHFPKVQ--WPPRELCAACHN-ELRG-TAVWDLNNTLRFLKTH
FSPSNVVLDTHSSRPGPR----MVAQRMA---------------ARNVTLSP-AKAAMVV
GLGTESPGTAVPDIVVERLG--------ASQPQDVLIGFGAT--TAEPEQGSPEHVAEL-
---QR-DEVEQSEGRQHVSRRDTGATLLEEFLAEKSQPRAPSELR-RVGRSSKQLA----
---------------SIPEGEP----EAGPMRGQGQWLQVLEGNFSHLDISLCVGLYSLS
FMGLLAVYTYFRARMRALKGHVGHPAA-

------------------------------------------------------------
------------MVGAEG-LHPGPGVQ----QA---LTIPAFVQATL-----ECFSGQQP
CDLGPDAGARLICQTL--AS-RLLSPQFLDSRCSHFWLGTQFLIPFTPV-----T--QTL
PTTTWRPALNLAALDCAEETNSAVCRDFNIPGFPTVRFFKAFSKNGS---GAVF---PVA
GADVQTLRERLIDAL---ESHH-DTWPPACP-PLEPAKLEEIDGFFARNKEEYLALIFET
GGSYLGREVALDLSQHKGVVVRRVLNTEADVVRKFGVTDFPSCYLLFRNGSVSRVP-VLM
ESRSFYTAYLQRLSGLTREAAQTT-VAPT------TANKIAPTVWKFADRSKIYMADLES
ALHYILRIEVGRF--PVLEGQRLVALK-KFVAVLAKYFPGRPLVQNFLHSVNEWLKRQKR
NKIPYSFFKT-ALDDRKE--GAVLAKKVNWIGCQGSEPHFRGFP

PF04777 // ENSGT00390000008045_0_Domain_2 (525, 628)

CSLWVLFHFLTVQAAR
QNV-DHSQEAAKAQEVLPAIRGYVHYFFGCRDCAGHFEQMAAASMHRVGSPNAAVLWLWS
SHNRVNARLAG-APSEDPQFPKVQ--WPPRELCSACHN-ERLD-VPVWDVEATLNFLKAH
FSPSNIILDFPAAGSAAR----RDAQNVAAAPELAVGALELEG-RNS-TLDPGKPEM-M-
---K-FPANTTPDVPAERPE--------ASRPPKLRPGLG-----AGPGQEPPEHMAEL-
---QR-NEREQPRGQWHLSKRDTGAALLAESRAEKNRLWGPSEVR-RVGRSSKQLV----
---------------DIPEGQL----EARAGQGRGQWLQVLGGGFSHLDISLCVGLYSLS
FMGLLAMYTYFRAKIRALKGHAGHPAA-

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------VTLDLSQRQGIAVRRVLNTERAVVNKFGVTDFPSCYLLFRNGSYSRIP-VXX
XXXXXXXXXXXXXXXXXXXXXXXX-XXXX---XX-XXXXXXXXXXXXXS--KIYMADLES
ALHYILRVEVGKF--SILEGQRLVALK-KFMAVLAQXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXX-XXXXXXX--XXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXK

PF04777 // ENSGT00390000008045_0_Domain_2 (553, 627)

AQEVLQAIRGYVRFFFGCRDCARHFEQMASASMHLVASPNSAALWFWS
SHNKVNARLAG-APSEDPQFPKVQ--WPPRELCSACHN-ELRG-APVWDLGNTLTFLKTH
FSPSNIVLGLPSAGLSPR----RGAQRMGVPPKQV--ELELAI-GNF-TLGPEKAE----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------

------------------------------------------------------------
----------MTRCVCL--LGP-----PPPPLLLL-LPLLLAVPGAGPARLGALYSSSDP
VTL

PF00085 // ENSGT00390000008045_0_Domain_0 (124, 222)

LQADTVR--GAVL--NSRSAWAVEFFASWCGHC-------IAFAPT-----WKALAN
DVKDWRPALNLAALDCADETNSKVCRDFNIPGFPSVRFFKA

ENSGT00390000008045_0_Linker_0_2 (222, 525)

FSKNGL---GTTL---PVA
GANVQTLRERLIDAL---ESHH-DTWPPACP-PLEPAKLEEIDGVFARNNEEYLALIFEH
EGSYLGREVTLDLSQHQGLAVRRVLNTEGNVVSKFGVTDFPSCYLLFRNGSVSRVP-VLK
ESRSFYTAYLQRLSGLTRESTPTT-AVPT------TPDKIAPTVWKFADHSKIYMADLES
ALHYILRVEVGKF--SVLEGERLVALK-KFVAVLAKYFPGQPFVQNFLHSINDWLKRQQR
KKIPYSFFKS-ALDSRKE--DAVLTKKVNWIGCQGSEPHFRGFP

PF04777 // ENSGT00390000008045_0_Domain_2 (525, 628)

CSLWVLFHFLTVQASQ
QSA-DHSQDPANGQEVLQAIRNYVQFFFGCRDCANHFEQMAAGSMNRVRSPNDAVLWLWT
SHNRVNARLAG-APSEDPQFPKIQ--WPPHELCSACHN-ELSG-EPVWDVGATLRFLKAH
FSPGNIVLHSPSSGPAPR----SSAHSLAAAPNLGVGALGLAI-RNS-ALGPEQADS-T-
---ESPGNTS-QQIPVFQLF--------EA----LP----HS--R---------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------

------------------------------------------------------------
----------MERCGRD--SRPPPTLL----LL---LLLPLAVPGAVAAPRSALYSPSDP
LTLLQADTVR--G

PF00085 // ENSGT00390000008045_0_Domain_0 (134, 224)

AVL--GSRSAWAVEFFASWCGH-----C--IAFAPT-----WKALAE
DVKAWRPALNLAALDCAEETNSAVCRDFNIPGFPTVRFFKAFS

ENSGT00390000008045_0_Linker_0_2 (224, 525)

KNSS---GAVF---PVA
GADVRTLRERLIDAL---ESHH-DTWPPACP-PLQPAKLKEIDGFFARNNEEYLALIFEK
GGSYLGREVALDLSQHKGVAVRRVLNTEAEVVRKFGVTNFPSCYLLFLNGSVSRVP-VLM
ESRSFYTAYLQRLSGLTREAPQTT-VAPT------TVNKIAPTVWKFADRSKIYMADLES
ALHYILRIEVGRF--SVLEGQRLVALK-KFVAVLAKYFPGQPLVQNFLHSVNEWLKRQKR
RKIPYSFFKT-ALDDRKE--GAVLAKKVNWIGCQGSEPHFRGFP

PF04777 // ENSGT00390000008045_0_Domain_2 (525, 628)

CSLWVLFHFLTVQAAR
QPV-DHSQEAAKAQEVLQAIRGYVRFFFGCRDCAGHFEQMAAASMDQVGSPDAAVLWLWS
SHNKVNARLAG-APSEDPQFPKVQ--WPPRELCSACHN-ERLD-VPVWDVEATLTFLKAH
FSPSNIVLGLPAVGSAPR----WDVQRVAAAPKLAMEGLALES-RNS-TLDPEKPEM-M-
---TQPPANTTPDVPAERPE--------ASHPPKLHPGLG-----AAPGQEPPEHMAEL-
---QR-NEWEQPRGQWHLNKRDKGAVLLAESWAEKNRPWGPLEVR-HVGRSSRQLV----
---------------DIPEGQL----EARARQGRGQWLQVLGGGFSHLDFSLCVGLYSLS
FMGLLAMYTYFRAKIRALKGHAGHPVA-

------------------------------------------------------------
----------MGRCNR-G-SGPPPSLL----Q--LLLLWLLAVPGANAAPRSALYSPSDP
LTLLQADTVR--G

PF00085 // ENSGT00390000008045_0_Domain_0 (134, 223)

AVL--GSRSAWAVEFFASWCGHC-------IAFAPT-----WKALAE
DVKAWRPALYLAALDCAEETNSAVCRDFNIPGFPTVRFFKAF

ENSGT00390000008045_0_Linker_0_2 (223, 525)

TKNGS---GAVF---PVA
GADVQTLRERLIDAL---ESHH-DTWPPACP-PLEPAKLEEIDGFFVRNNKEYLALIFEK
GGSYLGREVALDLSQHKGVAVRRVLNTEANVVRKFGVTDFPSCYLLFRNGSVSRVP-VLM
ESRSFYTAYLQRLSGLTREAAQTT-VAPT------TANKIAPTVWKFADRSKIYMADLES
ALHYILRIEVGRF--PVLEGQRLVALK-KFVAVLAKYFPGRPLVQNFLHSVNEWLKRQKR
NKIPYSFFKT-ALDNRKE--GAVLAKKVNWIGCQGSEPHFRGFP

PF04777 // ENSGT00390000008045_0_Domain_2 (525, 628)

CSLWVLFHFLTVQAAR
QNV-DHSQEAAKAKEVLPAIRGYVHYFFGCRDCASHFEQMAAASMHRVGSPNAAVLWLWS
SHNRVNARLAG-APSEDPQFPKVQ--WPPRELCSACHN-ERLD-VPVWDVEATLNFLKAH
FSPSNIILDFPAAGSAAR----RDVQNVAAAPELAMGALELES-RNS-TLDPGKPEM-M-
---K-SPTNTTPDVPAEGPE--------ASRPPKLRPGLG-----AAPGQEPPEHMAEL-
---QR-NEQEQPLGQWHLSKRDTGAALLAESRAEKNRLWGPLEVR-RVGRSSKQLV----
---------------DIPEGQL----EARAGRGRGQWLQVLGGGFSYLDISLCVGLYSLS
FMGLLAMYTYFQAKIRALKGHAGHPAA-

------------------------------------------------------------
------------------------------------------------------------
-----------------------------ASWCGHC-------IAFAPK-----WKALAK
EVKXXXXXXXXXXXXXXXXXXXXXXXXXXX-------------XX-----XXXXXXXXXX
XXXXXXXXXXLIDAL---ETHRGGRWPPSCP-ELAPIRLEEINNFFLRNSDDYLALIFEK
KDSYVGREXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XX
XXXXXXXXXXX---XXXXXXXXXXXXXXX---XXXXXXXXXXXXXXXXXXSKVYMTDLES
ALHYILRVEVGKF--KVLEGERLTALK-KFVSVLAKXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXX-XXXXXXX--DVILPRKSIWVGCQGSEPHFRGFPCS

PF04777 // ENSGT00390000008045_0_Domain_2 (527, 627)

LWILFHSLTVQAAL
RNEYL---SKKAAQEVLQAIRGYVKFFFGCRECAKHFEQMAAASMDQVKSMDDAILWFWN
RHNRVNARLAG-TASEDPHFPKIQ--WPPRELCDLCHN-EIQG-DPVWNLGATLKFFKSH
FALRNIVIDHKWSTEAL-----PGWKVVQG---------------AA--------AT---
--TESPRGAWT------------------NRNSDLASGK---------------------
---------------------------L-HTW----QKKSPTNTR-VQVEGTKQMS----
---------------SFSKRKVG-----ARAQPGGQWLWMLRGSFSYLDAGFCIGLYSLS
FICLIVMCTYFQERMKARKGRSIYFSA-

------------------------------------------------------------
-MWRRRARSGGGGGGGGGGAAPRCRWWP-----AVLALLAAAL---PAARSRSLYSPSDP
LELLGADTAE--RRLL--GS

PF00085 // ENSGT00390000008045_0_Domain_0 (141, 225)

PSAWAVEFFASWCGHC-------IHFAPT-----WRALAE
DVREWRPAVMIAALDCADEANQQVCADFGITGFPTLKFFRAFSK

ENSGT00390000008045_0_Linker_0_2 (225, 525)

KAED--GIRI---AHP
TATVADLRRAIITNL---EQSG-DAWPPACP-PLEPASAEEVRSFFHRNTERYLALIFEQ
SNSFVGREVALDLLQYENVAVRRVLSSEEELVEKFGVTTFPSAYLLLRNGSFSRLP-VHA
EARSFYTYYLQTLSGVTRGSYRLNVTGSA------INE-TRALQPAQADRSKVYVADLES
TVHYTLRVEAGRP--AVLAGAQLAALK-CYVATLAKYFPGRPSVQTFLQSLDSWLRNWTE
PELPRSALKEAVKNKEDASPAAVLPTNVTWVGCRGSEPHFRGYP

PF04777 // ENSGT00390000008045_0_Domain_2 (525, 628)

CGLWTIFHLLTVQAAQ
GGP-----DEELPLEVLNTMRCYVKHFFGCQECAQHFEAMAAKSMDQVKSRREAVLWLWS
HHNEVNARLAG-GDTEDPQFPKLQ--WPPPDMCPQCHR-EERG-VHTWDEAAVLSFLKEH
FSLGNLYLDHAIPIPMAGEEAAASA-RLSTAGLREKEEEERKEEEE---EG--EKET--E
KPHRE--------GETGRPG-----SSELRRPSIVRRN--PRLRALGEDIVDLDSFSEQH
FKSKALRA-A--GRHRRLSKRDTVALHHD--------AG--WERLQVP------------
----------------E----SREEEEEGGVLRRSPWLRVLGLGFSRLDVSLCIALYFLS
SMCLLGMYTFFRLRTRARKGRPGFPVA-

------------------------------------------------------------
----------MGRCNR-G-SGPPSSLL----LLLLLLLWLLAVPGASAAPRSALYSPSDP
LTLLQADT

PF00085 // ENSGT00390000008045_0_Domain_0 (129, 224)

VR--GAVL--GSRSAWAVEFFASWCGHC-------IAFAPT-----WKALAE
DVKAWRPALNLAALDCAEETNSAVCRDFNIPGFPTVRFFKAFT

ENSGT00390000008045_0_Linker_0_2 (224, 525)

KNGS---GAVF---PVA
GADVQTLRERLIDAL---ESHH-DTWPPACP-PLEPARLEEIDGFFARNNEEYLALIFEK
GGSYLGREVALDLSQHKGVAVRRVLNTEANVVRKFGVTDFPSCYLLFRNGSVSRVP-VLM
ESRSFYTAYLQRLSGLTREAAQTT-VAPT------TANKIAPTVWKFADRSKIYMADLES
ALHYILRIEVGRF--PVLEGQCLVALK-KFVAVLAKYFPGRPLVQNFLHSVNEWLKRQKR
NKIPYSFFKT-ALDDRKE--GAVLAKKVNWIGCQGSEPHFRGFP

PF04777 // ENSGT00390000008045_0_Domain_2 (525, 628)

CSLWVLFHFLTVQAAR
QNI-DRSQEAAKAKEVLPAIRGYVHYFFGCRDCASHFEQMAAASMHRVRSPNAAVLWLWS
SHNRVNARLAG-APSEDPQFPKVQ--WPPRELCSACHN-ERLD-VPVWDVEATLNFLKAH
FSPSNIILDFAAAGSAAQ----REAQNVAAAPELAMGALELES-RNS-TVDLGKPEM-M-
---K-SSTNTTPDVPAERPE--------LI------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------

------------------------------------------------------------
----------MGWCGRG--SGP-----PP-SRLLMLLSLLLAVRGAGAAPRSALYSSSDP
LTLL

PF00085 // ENSGT00390000008045_0_Domain_0 (125, 225)

QADTLR--RTVL--GSRSAWAVEFFASWCGHC-------IAFAPT-----WKALAN
DVKDWRPALNLAALDCAEETNSAVCRDFNIPGFPTVRFFKAFSK

ENSGT00390000008045_0_Linker_0_2 (225, 525)

TGS---GTTL---SVA
GADVQTLRERLIDAL---ESHS-DTWPPACP-PLEPARLEEITGFFSRNDEEYLALIFEK
EGSYLGREVTLDLSQHQGIAVRRVLNTERDVVNKFGVTNFPSCYLLSRNGSFSRVP-ALT
ESRSFYTTYLRKFSGTTRGAVQTT-AAPA------TTSAVAPTVWKVADRSKIYTADLES
ALHYILRIEVGKF--SVLEGQRLVALK-KFMAVLAQYFRGRPLVQNFLHSMNDWLKKQQR
KKIPYGFFKN-ALDSRKE--GTVIAEKVNWVGCQGSEPHFRGFP

PF04777 // ENSGT00390000008045_0_Domain_2 (525, 628)

CSLWILFHFLTVQAAQ
EGV-DHSQERAKAQEVLQAIRGYVRFFFGCRECAGHFEQMASRSMHRVGSLNSAVLWFWS
SHNKVNARLAG-APSEDPQFPKVQ--WPPRELCSACHN-ELRG-APVWDLDNILNFLKTH
FSPSNTVLDLPSAGPGPR----RGAERMAVIPKQVE--LELA--AGNVTLAP-EKAEIPV
GSGIKAPGASIPVAGLG-----------AS-HPKMQAGLGAA--TDEPDPGTPEHAVEL-
---QR-DKLEQPEGEQRLSRRDTGAVLLAEFLAGRNLPRGPSELG-RVGRSSQQLA----
---------------GIPDGEP----EAGAGQGQAQWLQMLGGNFSHLDISLCVGLYSLS
FMGLLAVYTYFRARIRALKGYTSLPAA-

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----WRPVLNLAVLDCAEETNTAVCRDFNISGFPTVRFFKAFSKNGS---GITL---PVA
DASVETLRRKLIDAL---ESHS-DMWSSSRP-KLKPAKLVEINEFFAETNEDYLVLIFED
KDSYVGREVTLDLFQHH-IPVHRVLNTERNAVSKFGVVEFPSCYLLFRNGSFSRVP-VVM
ESRLFYTSYLKGMSGPILVDPPTT-TIST---DAPVTTDVVPTVWKVANHARIYMADLES
SLHYIFLVEVGKF--SVLEGQRLLALK-KLVAVLAKYFPGRPLAQNFLHSIHDWLQRQQR
KKIPYKFFRA-ALDNRKE--GIVLTEKVNWVGCQGSKPHFRGFP

PF04777 // ENSGT00390000008045_0_Domain_2 (525, 628)

CSLWILFHFLTVQASR
YSE-NHPQEPADGQEVLQAMRSYVQWFFGCRDCAEHFENMAASTMHRVRSPTSAVLWLWT
SHNKVNARLSG-APSEDPYFPKVQ--WPLRELCFDCHN-EINGREPVWDLEATYRFLKAH
FSSENIILDTPVAGLATQ----RNPQILGATPEPVMDALELET-RNS-VLGHERAAS---
---TESPGATALNVPVGKPE--------ASGPQALYT-----------GQGPPEHMEEP-
---QR-VTQGHTQGQQHLSKRDTEVLTLPE----VNHLQGPLELR-RGGRSPKQLV----
---------------NIPEGEP----EAPAIRGQGPWLQVLGRGFSHLDISLCVGLYSVS
FVCLLAMYTYFRARLRTPKGHSHPIA--

------------------------------------------------------------
----------MRRCGRS--CRPPPSLL------LLLLLLLLAVPGAGAARRSALYSPSDP
LTLLQAD

PF00085 // ENSGT00390000008045_0_Domain_0 (128, 217)

TVR--GAVL--DSRSAWAVEFFASWCGHC-------IAFAPT-----WKALAN
D----------------------------------V

ENSGT00390000008045_0_Linker_0_2 (217, 525)

KFFKAFAKSGS---GATL---PVA
GADVQTLRERLIDAL---ESHR-DTWPPACP-PLEPAKLADIDGFFARNNEDYLALIFEK
EGSYLGREVTLDLSQHQGIVVRRVLNTEDNVVRKFGVTDFPSCYLLFRNGSVSRVS-VVV
ESRAFYTDYLKRLAGLTREAARTT-VAPT------TANSIAPTVWKLADRSKIYMADLES
ALHYILRVEVGKF--SVLEGQRLVALK-KFVAVLAKYFPGSPLVQNFLHSVNEWLKRQQR
KKIPYSLFKT-ALDNRKE--GAVLAEKVNWVGCQGSEPHFRGFP

PF04777 // ENSGT00390000008045_0_Domain_2 (525, 628)

CSLWLLFHLLTAQAAR
HKV-DHPREKAQAQEVLQAIRGYVRAFFGCRDCAGHFEQMAAASMHKVGSLDDAVLWFWS
SHNRVNARLAG-APSEDPQFPKVQ--WPPRELCSACHN-ELAG-VPVWDMGATLSFLKAH
FSPSNIVLDPPPAGPAPR----SGTQNLTATPKLALGSLELET-GNS-TLGPEKAEV-A-
---KSPGTTVPDVPT-ERPE--------ASRTPELHAG--------SD-QGPPEPATEL-
---QGGDKPGQPRVLRHLSKRDSGAALLAEPGAEKNRPGGPVGLR-RIGRSSKQLA----
---------------DVPAWEL----EARAQQGRGRWLQVLGGGFSRLDVSLCVGLYSLS
FMGLLALYTYFRAKMRAPKGPAGHPAA-

------------------------------------------------------------
----------MGRYGRH--SGPRRSLLPPPPLLLLLPSLLLLAPDAGAAQLSVLYSASDP
LTLLQADT

PF00085 // ENSGT00390000008045_0_Domain_0 (129, 223)

VR--GTVL--DSSGAWAVEFFASWCGHC-------IAFAPM-----WKALAE
DVKGWRPVLNLAVLDCAEEVNNAVCRDFNIRGFPTVRFFKAF

ENSGT00390000008045_0_Linker_0_2 (223, 525)

SKSGS---GAVL---PVA
GATVQILRERLIDAL---ESHS-DTWPQDCP-PLEPAKLEEIIGFFPRSNEEYLALIFEK
EGSYLGREVILDLSQYHGLAVRRVLDTEDYVVAKFGVSDFPSCYLMSRNGSVARVP-VLV
ESRSFYTSYLQRLAGITREASPTT-AQPA------VTDNVAPTVWKLADRSKIYMMDLES
ALHYILRVEVGKF--SILEGQRLIALK-NFVAVLAKYFPGQPLVQNFLHSVSDWFMKQQR
RKIPYNFFKI-ALDSRRE--DSVLPEKVHWVGCQGSQPHLRGFP

PF04777 // ENSGT00390000008045_0_Domain_2 (525, 628)

CSLWVLFHTLTVQASQ
QSA-DHSREPANGQEVLQAIRNYVRYFFGCRECAGHFEQMAAASMHKVGSPNDAVLWLWT
SHNKVNARLAG-APSEDPQFPKIQ--WPPRELCSTCHN-ELNG-APVWDVDATLGFLKDH
FSSRNIVLDSPTAGLAHQ----RGVQSFTNTPKLVMGAWKLPT-RIS-ALGLQQAGT-A-
---GSPRPEA-SGPQDLYPS--------------LG----MT--RPVPGQGKAEHVREL-
---QR-DVAEQLQGQRHLSKRDTGALLLAESWAEV-SHLQ---GP-LGGHGSKQLA----
---------------SRPGGEP-------AVRGQGHWLRVLGGGFSHLDVSLCVGLYSLS
FMGLLAVYTYFRARMRALKGHAGHPVA-

-----------------------------------------------------------A
SADSQGGARHLGAKARL--PGP-----PLRNCGARGGATWLLLAGGG----------QAK
VRRGSADTVR--G

PF00085 // ENSGT00390000008045_0_Domain_0 (134, 222)

AVL--NSRSAWAVEFFASWCGHC-------IAFAPT-----WKALAN
DVKDWRPALNLAALDCADETNSKVCRDFNIPGFPSVRFFKA

ENSGT00390000008045_0_Linker_0_2 (222, 525)

FSKNGL---GTTL---PVA
GANVQTLRERLIDAL---ESHH-DTWPPACP-PLEPAKLEEIDGVFARNNEEYLALIFEH
EGSYLGREVTLDLSQHQGLAVRRVLNTEGNVVSKFGVTDFPSCYLLFRNGSVSRVP-VLK
ESRSFYTAYLQRLSGLTRESTPTT-AVPT------TPDKIAPTVWKFADHSKIYMADLES
ALHYILRVEVGKF--SVLEGERLVALK-KFVAVLAKYFPGQPFVQNFLHSINDWLKRQQR
KKIPYSFFKS-ALDSRKE--DAVLTKKVNWIGCQGSEPHFRGFP

PF04777 // ENSGT00390000008045_0_Domain_2 (525, 628)

CSLWVLFHFLTVQASQ
QSA-DHSQDPANGQEGLQAIPNYVQFFFGCRDCANHFEQMAAGSMNRVRSPNDAVLWLWT
SHNRVNARLAG-APSEDPQFPKIQ--WPPHELCSACHN-ELSG-EPVWDVGATLRFLKAH
FSPGNIVLHSPSSGPAPR----SSAHSLAAAPNLGLFEA---------------------
----------------------------------LP----HS--R---------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------

------------------------------------------------------------
-----------------------------------------------AAPRSALY-SSSH
LALLQADTVR--GA

PF00085 // ENSGT00390000008045_0_Domain_0 (135, 225)

LL--GSRSAWAVEFFASWCGHC-------IAFAPT-----WKALAQ
DVKDWRPALNLAALDCADETNNAVCRDFNIPGFPTVRFFKAFSK

ENSGT00390000008045_0_Linker_0_2 (225, 525)

NGS---GTTL---PVA
GADVETLRKRLIDAL---ESHS-DTWPPACP-PLEPARLEEIDGFFARNDDEYLALIFEK
EGSYLGREVALDLSQHQGIAVRRVLNTEGDVVSKFGVTDFPSCYLLFRNGSTSRVH-VLQ
ESRPFYTAYLKKFSKLIREAVPTK-VVPT------TVHTIAPTVWKVVDRSKIYMADLES
ALHYILRVEVGKF--SVLEGQRLVALK-KFMAVLAQHFPGQPLVQNFLHSVNDWLKRQQR
KKIPYSFFKA-ALDNRKE--GTMIAKKVHWVGCQGSEPHFRGFP

PF04777 // ENSGT00390000008045_0_Domain_2 (525, 628)

CSLWILFHFLTVQAAR
HNL-DHSQETAEAQEVLQAIRSYVRFFFGCRDCANHFEQMAAASMNRVDSLNSAVLWLWS
SHNKVNARLAG-AASEDPHFPKVQ--WPPRGLCSACHN-DLRG-SPVWDLDNTLRFLKTH
FSPSNVVLDMPSAVPGPQ----MGALRMA---------------AGNVTLGP-KKAGIAV
GPGTKSPGTTVPEVPTERLS--------ATYPQDMLLGLSVT--PAEPDRGSREHRAEL-
---QM-DKLEQPKGQQHLTKRDTGTVLLAEFLAEKNLPRNPSELR-RVGRSSKQLA----
---------------SIPEGEP----EAGPMGGRDQWLQVLEGNFSHLDISLCVGLYSLS
FMGLLAIYTYFRARMRALKGHPGHPAA-

------------------------------------------------------------
----------MGWCGRG--SGP-----PP-SRLLMLLSLLLAVRGAGAAPRSALYSSSDP
LTLLRAGAVR--R

PF00085 // ENSGT00390000008045_0_Domain_0 (134, 225)

TVL--GSRSAWAVEFFASWCGHC-------IAFAPT-----WKALAN
DVKDWRPALNLAALDCAEETNSAVCRDFNIPGFPTVRFFKAFSK

ENSGT00390000008045_0_Linker_0_2 (225, 525)

TGS---GTTL---SVA
GADVQTLRERLIDAL---ESHS-DTWPPACP-PLEPARLEEITGFFARNDEEYLALIFEK
EGSYLGREVTQDPPQHQGIAVRRVLNTERDVVNKFGVTNFPSCYLLSRNGSFSRVP-ALT
ESRSFYTTYLRKFSGTTRGAVQTT-AAPA------TTSAVAPTVWKVADRSKIYTADLES
ALHYILRIEVGKF--SVLEGQRLVALK-KFMAVLAQYFRGRPLVQNFLQSMNDWLKKQQR
KKIPYGFFKN-ALDSRKE--GTVIAEKVNWVGCQGSEPHFRGFP

PF04777 // ENSGT00390000008045_0_Domain_2 (525, 628)

CSLWILFHFLTVQAAQ
EGV-DHSQERAKAQEVLQAIRGYVRFFFGCRECAGHFEQMASRSMHRVGSLNSAVLWFWS
SHNKVNARLAG-APSEDPQFPKVQ--WPPRELCSACHN-ELRG-APVWDLDNILNFLKTH
FSPSNTVLDLPSAGPGPR----RGAERMAVIPKQVE--LELA--AGNVTLAP-EKAEIPV
GSGIKAPGASIPVAGLG-----------AS-HPKMQAGLGTA--T---DPGAPEHAVEL-
---QR-DKLEQPEGEQRLSRRDTGAVLLAEFLAGRNLPGGPSELG-RVGRSSQQLA----
---------------GIPDGEP----EAGAGQGQAQWLQMLGGNFSHLDISLCVGLYSLS
FMGLLAVYTYFRARIRALKGYTSLPAA-

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---DWRPALNLAALDCADETNSAVCRDFNIAGFPTVRFFKAFSKSGP---GATL---AVA
GADMQTLRERLIDAL---ETHG-ATWPPACP-PLEPTGLEEIDGFFARNDEECLALIFEK
KGSYLGREVILDLSQREGIAVRRVLNTEGDVVSKFGVTDFPSCYLLFRNGSASRVP-VLM
ESRSFYTNYLQRFAGATREAARTT-VPPI------TANTVAPTAWKVADRSKIYMADLES
ALHYILRVEVGKF--SLLEGQRLVALK-KFVAVLAQYFPGQPLVQNFLHSVNDWLQKQQR
KKIPYGFFQT-ALENRKE--GVVIAKKVNWVGCQGSEPHFRGFPCS

PF04777 // ENSGT00390000008045_0_Domain_2 (527, 615)

LWVLFHFLTVQATR
QNV-DRSQETAKAQEVLQAIRGYVRFFFGCRDCAGHFEKMAAASMHRVGSRDSAVLWLWS
SHNKVNARLAG-PALLMPLLLFPCTRAPPSGLVGSLSCLPILL-SGYWPLTQTNRKVRAG
LFKPPLP---PREESNDK----MGWKRK------TR--FFLEI-RTDFTGGP-GLLSSLV
GSASVPWAQESDGSSGREPS--------VGGSLGLSVGREEY--ACLGQTTPPEHIAEL-
---QR-ERWEQPEGQEPLSERDLGAGLLAELPA-EDLPTGPSERR-RVGRSSKQLA----
---------------SVPEGEP----EAGALRGRGQWLQVLEGNFSHLDISLCVVLYSLS
FMGLLAMYTYFRARMRALKGHASHPAA-

------------------------------------------------------------
----------MGRCGR-G-SEPLPSLL----L---LLLLLLAVPGAGAAPRSALYSPSDP
LTLLQADTVR--G

PF00085 // ENSGT00390000008045_0_Domain_0 (134, 223)

AVL--GSRGAWAVEFFASWCGHC-------IAFAPT-----WKALAE
DVKAWRPALNLAALDCAEETNSAVCRDFNIPGFPTVRFFKAF

ENSGT00390000008045_0_Linker_0_2 (223, 525)

SKNGS---GAVF---PVA
GADVQTLRERLIDAL---ESHH-DTWPPACP-PLEPAKLEEIDGFFARNKEEYLALIFEK
GGSYLGREVALDLSQHKGVTVRRVLNTEADVVRKFGVTDFPSCYLLFRNGSVSRVP-VLM
ESRSFYTAYLQRLSGLTREAAQTT-VAPT------TANKIAPTVWKFADRSKIYMADLES
ALHYILRIEVGRF--PVLEGQRLVALK-KFVAVLAKYFPGRPLVQNFLHSVNEWLKRQKR
NKIPYSFFKT-ALDDRKE--GAVLAKKVNWIGCQGSEPHFRGFP

PF04777 // ENSGT00390000008045_0_Domain_2 (525, 628)

CSLWVLFHFLTVQAAR
QNV-DHSQEAAKAQEVLPAIRGYVHYFFGCRDCAGHFEQMAAASMHRVGSPNAAVLWLWS
SHNRVNARLAG-APSEDPQFPKVQ--WPPRELCSACHN-ERLD-VPVWDVEATLRFLKAH
FSPSNIILDFPAAGSAAR----REAQNVAAAPELAMGSLELEG-RNS-TLDPGKPEM-M-
---K-SPANTTPDVPVERPE--------ASRPPKLRPGLG-----AAPGQEPPEHMAEL-
---QR-KEWEQPRGQWHLSKRDTGAALLAESRAEKNHLWGPSEVR-RVGRSSKQLV----
---------------DIPEGQL----EARAGRGRGQWLQVLGGGFSHLDISLCVGLYSLS
FMGLLAMYTYFRAKIRALKGHVGHPAA-

------------------------------------------------------------
--MGRRRHCSAAAVGARG-RPPPPP--------LLLLLLLLAVPGAGAALRSALYAASDP
LTLL

PF00085 // ENSGT00390000008045_0_Domain_0 (125, 221)

QADTVR--DAVL--GSRSAWAVEFFASWCGHC-------IAFAPT-----WKALAN
DVKDWRPALNLAALDCAEETNNAVCRDFDIPGFPTVRFFK

ENSGT00390000008045_0_Linker_0_2 (221, 525)

AFSMNGS---GAAL---SVA
GADVQVLRERLIDAL---ESHQ-DTWPPACP-PLEPARLEEINGFFARNNEDYLAVIFEK
EGSYLGREVILDLSQYHGVTVLRVLNTEDDAVSKFGVTDFPSCYLLFRNGSVSRIP-VLV
ESRSFYTAYLKRLPGLTRDPPQTT-VTPT------TANRIAPTVWKLADHSKIYMADLES
ALHYILRVEVGKF--SVLEGQRLVALK-NFVAVLAKYFPGQPLVQNFLHSTNDWLRRQQR
KKIPYSFFKT-ALDNRNE--GAVIAKKVNWVGCQGSEPHFRGFP

PF04777 // ENSGT00390000008045_0_Domain_2 (525, 628)

CSLWLLFHFLTVQAAR
QNI-IHPQEEGPQSKGLPEARGSRGNWAGCRDCARHFERMAAASMHGVESLDKAVLWLWS
AHNKVNARLAG-APSEDPQFPKVQ--WPPRTLCSACHN-ELQG-DPVWDLDATLRFLKTH
FSLSNMVRHLPGARLPPH----AAAERRAAIPGV----RVLAT-GDP-PLGAEEGAGITV
SPGTGPAETTILGVPAERPG--------ARPPREPGVGLGTA--STEPHQGPPELVAES-
---QR-DELEQPQGQRRLSKRDTGAVLLAEFQADKDLLAGPPRPR-RVGRSSKQLA----
---------------IISEGEP----EARAVRGPGQWLQVLEGGFSHLDVSLCVGLYSLS
FMGLLAMYTYFRARMRALKGRASHPTA-

------------------------------------------------------------
------------------------------------------V---PAARPGRLYSASDP
LELLGPGAE----GLL--LGFHAWAG

PF00085 // ENSGT00390000008045_0_Domain_0 (147, 222)

KFYDSWCGHC-------IHFAHS-----WRDLAH
DIREWRPAVILAAIDCADEDNQQVCSDFGITGFPTMKFFRA

ENSGT00390000008045_0_Linker_0_2 (222, 525)

FSNKPED--GIRI---TNP
SATVEDLRHAIITNL---EQSQ-DAWPPACP-PLEPASAEEVRTFFQRNKDQYLALIFEK
SNSFVGREVALDMLQYENIAVRRVLSSEEELVQKFGVTSFPSGYLLFRNGSFSRLP-VHV
EARSFYTYYLRTLTGIARGSYKLNATASA------LNDTDRVSHPLRADRSKLYMADLES
ALHYSLRVEAARA--SSLSGAQLAAFK-CYVATLVKYFPGRPCVQTYLQTLDAWLKNWTE
PELPRTVLKEAMKNNRDASQPSVLPTNVTWVGCQGSERHFRGYP

PF04777 // ENSGT00390000008045_0_Domain_2 (525, 628)

CGLWTIFHLLTVQAAQ
NGP-----DKELPLEVLSTMRCYVRHFFGCQECAEHFEAMAAKSMDGVASREEAVLWLWS
HHNEVNARLAG-GDTEDPKFPKLQ--WPPPDLCPQCHK-EERG-VHAWEEPAVLMFLKAH
FSPANIYMDYAEPDPIPVAREGT-GARLDTESPREER-GRGEAEER---EP--EGEA--R
--------------------------VEPRRPSIVRLN--PKLREGGEDIVDLDSFSEQH
FKSQALRAAA--GRRRRISKRDTMALPRG--------AAAGRERRHAP--------G---
---------------VL----LRD-QEAAEGLRRSPWLRVLGLGFSRLDISLCVALYFLS
SMCLLAMYTFFRLRTRARKGRPGFPMA-

------------------------------------------------------------
----------MGRCGR-G-SEPLPSLL----L---LLLLLLAVPGAGAAPRSALYSPSDP
LTLLQADTVR--G

PF00085 // ENSGT00390000008045_0_Domain_0 (134, 223)

AVL--GSRGAWAVEFFASWCGHC-------IAFAPT-----WKALAE
DVKAWRPALNLAALDCAEETNSAVCRDFNIPGFPTVRFFKAF

ENSGT00390000008045_0_Linker_0_2 (223, 525)

SKNGS---GAVF---PVA
GADVQTLRERLIDAL---ESHH-DTWPPACP-PLEPAKLEEIDGFFARNKEEYLALIFEK
GGSYLGREVALDLSQHKGVMVRRVLNTEADVVRKFGVTDFPSCYLLFRNGSVSRVP-VLM
ESRSFYTAYLQRLSGLTREAAQTT-VAPT------TANKIAPTVWKFADRSKIYMADLES
ALHYILRIEVGRF--PVLEGQRLVALK-KFVAVLAKYFPGRPLVQNFLHSVNEWLKRQKR
NKIPYSFFKT-ALDDRKE--GAVLAKKVNWIGCQGSEPHFRGFP

PF04777 // ENSGT00390000008045_0_Domain_2 (525, 628)

CSLWVLFHFLTVQAAR
QNV-DHSQEAAKAQEVLPAIRGYVHYFFGCRDCAGHFEQMAAASMHRVGSPNAAVLWLWS
SHNRVNARLAG-APSEDPQFPKVQ--WPPRELCSACHN-ERLD-VPVWDVEATLRFLKAH
FSPSNIILDFPAAGSAAR----REAQNVAAAPELAMGSLELEG-RNS-TLDPGKPEM-M-
---K-SPANTTPDVPVERPE--------ASRPPKLRPGLG-----AAPGQEPPEHMAEL-
---QR-KEREQPRGQWHLSKRDTGAALLAESRAEKNHLWGPSEVR-RVGRSSKQLV----
---------------DIPEGQL----EARAGRGRGQWLQVLGGGFSHLDISLCVGLYSLS
FMGLLAMYTYFRAKIRALKGHVGHPAA-

------------------------------------------------------------
----------MRRCGRR--SGP-----LLPLLLL------LAAPGALAAPRSALYSPSDP
LTLL

PF00085 // ENSGT00390000008045_0_Domain_0 (125, 223)

QADTLR--GAVR--GSRSAWAVEFFASWCGHC-------IAFAPT-----WKALAR
DVKDWRPALNLAALDCADETNSAVCRDFNIPGFPTVRFFKAF

ENSGT00390000008045_0_Linker_0_2 (223, 525)

SKDGS---GTTL---PVA
GADVPTLRERLIDAL---ETHR-DTWPTACP-PLEPARMKEIDGFFARSDKEYLALIFEK
EGSYLGREVTLDLSQHQGMAVRRVLNTESDVVSRFGVTDFPSCYLLSRNGSVSRVP-VLK
ETRAFYTAYLQRLSGLTREASRST-VAPT------TAHRIAPTVWKSADRSKVYMADLES
ALHYILRVEVGRF--SLLEGQRLVALK-KFVAVLAKYFPGRPLVQNFLYSVNDWLKRQQK
KKIPYSFLKT-ALDSRKE--DAVLAKKVNWIGCQGSEPHFRGFP

PF04777 // ENSGT00390000008045_0_Domain_2 (525, 628)

CSLWVLFHFLTVQASR
RSA-NHPQEAVKGQEVLQAIRGYVRFFFGCRECAGHFEQMAAASMHKVGSPNDAVLWLWS
SHNRVNARLAG-APSEDPQFPKVQ--WPPRELCSACHN-ELQG-TPVWDVGATLNFLKGH
FSPGNIALDPPPAGRAPR----RGPQAVAAAPKLVVGALELTT-GNA-TLEAESPRA---
--------TV-PGAAAQGPE---------AGHPE------------------P----EP-
---QG-AV----LGQRRLSRRDTGAVL----LAGN-QPRGPSELR-RVGRGAELLA----
---------------GILEEEP----RAGARRAPGQWLQVLGGGFSHLDASLCVGLYSLS
FMGLLAVYTFFRARIRALKGHAGHSAA-

------------------------------------------------------------
----------MTKSGRQ--SGP-----P-PPLLLPLLPLLLAVPAAGAARLGALYLSSDP
VTL

PF00085 // ENSGT00390000008045_0_Domain_0 (124, 224)

LQADTVR--GAVL--NSRSAWAVEFFASWCGHC-------IAFAPT-----WKALAE
DVKGWSPVLKLAVLDCADETNNAVCRDFNILGFPSVRFFKAFT

ENSGT00390000008045_0_Linker_0_2 (224, 525)

KNGS---GTTL---PVA
GANVQTLREKLIDAL---ESHR-DTWPPACP-PLEPAKLEEIDGFFARNDEEYLALIFEQ
EGSYLGREVALDLSQHQGMAVRRVLNTEGPVVSKFGVTDFPSCYLLFRNGSVSRVP-ALM
ESRSFYTAYLQRLSGLTREATPTT-AVPT------TPDKIAPTVWKFADRSKIYMADLES
ALHYILRVEVGKF--SVLEGQRLAALK-KFVAVLAKYFPGQPLVQNFLHSTNDWLKRQQR
KKIPYSFFKT-ALDSRKE--DAVLTKKVNWVGCQGSEPHFRGFP

PF04777 // ENSGT00390000008045_0_Domain_2 (525, 613)

CSLWLLFHSLTVQASQ
QNA-DGSQEPASGQEVLQAIRNYVRFFFGCRDCADHFEQMAAGSMHRVRSPNDAVLWLWT
SHNRVNARLAG-KEGPPSRL----------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------