Query Results 

MSEVQGTVEFSVELHKFYNVDLFQRGYYQIRVTLKVSSRIPHRLSASIVGQTDSS----S
LRSAYAHENAVHSRVFQILYRNEEVSINDAVLFRAHLLLDGERVEEALSEVDFQ

PF12394 // ENSGT00390000007885_1_Domain_0 (115, 178)

LKVDLH
FTDSEQQ-LRDVAGAPLISSRTLGLHFHAWRGLHHQVPVMFDYFHLSVISVTIHAAL

ENSGT00390000007885_1_Linker_0_1 (178, 323)

VAL
QQPLISFTRPGRGSWLGKGGPDTGPEPSSLSLENLVFGAGYCKPTSS-EGSFYVPSENCM
QHAHRWHRQLCRLLLRAYGGLRAYFLAIMRDIPELPHMEL-ESLAVEETLSQLCSELQML
NNPEKIAE--QISKDLAWLTS-

PF12394 // ENSGT00390000007885_1_Domain_1 (323, 381)

HLMALWTQFLDTVTLHSQVTSYLTQEHHTLRVRRFSEA
F--FYMEHQKLAVLTFQENL

ENSGT00390000007885_1_Linker_1_2 (381, 1464)

IQTHSQLSLDIRNSEYLTTMPPLPAECLDIDGDWNTLPVI
FEDRYVDCPAT-GH--NL-------SIYP--NFDVPT---SPAIMNLNNREE--------
-----------------------NPTVNRKSPF--REDLV-LPTV--KP--PQVD-----
--------------SDR-EVIGCPEPEDKVIT-------PQCTDTC---SE---------
S-QVYLTIGECQNKAG-LP-------EEEC------------------------------
--------------WTGQRSDLGTHSLAD--------EDPPRRS---PGP----------
---------EDGQVPALTYIDVKSSNKRPCSM-----EPTVVISAQQESGHSPDSCESDR
AVPGQEVAG--------VGHQNAILSEKTTPH--ELS---T--LGQVADQEGK-------
----MALLSLKLIP---SEPCDP-LNSTLRDPLDVRASPKDPHSEEQEEVSVISGVIKRS
SSIISDSGIESEPSSVAWSEARSRALELPSDREVLHHLVRRHALHRNSLEGGHTESNTSL
PSGIQASLTSISSLPFEDEERELA-LTKLTKSVSAPQISSPEESAEDTDTMQQGGDLAES
PAIPMES--------V-------DSPASKIPD------------------AGADHSLVQ-
-VVSGA----DGQLVPGYIDIPKGTESQSDPQEPS-----------------CLDGRTEN
L--VGVET----KGLNV-KIPRIIALENPRHGSYP---RVLKETPEGKPEDL--NVENNA
PSNSS--ISDDETIAHH--KV--PE---W-NSRTAADVSD-----LESTDEQN--SSPGI
VDDAAFS-E---------GTQAHLEAGREAG----TVGST------VTPSTHSQVLGNQE
PKTGTSVMASHLGSVETFTLDSLKAVEVVNLSVSCTATCLPFSSVPKETPARAGFSAKQT
PLPITHQPLGSFGVVSTHSSKLEEEVSERMYS----FYQAKEKFKKELKIDGFLYSDLSV
LASDIPYFPPEEEEENLEDGIHL

PF07819 // ENSGT00390000007885_1_Domain_2 (1464, 1586)

VVCVHGLDGNSADLRLVKTFIELGLPGGKLDFLMSEK
NQ-MDTFADFDTMTDRLLDEIIQHIQLYNLS-ISRI--SFIGHSLGNII-IRSVLTRPRF
RYYLNKLHTFLSLSGPHLGTLYNNSTLVSTGLWLMQKLKKSGSLLQLTFRDNADLRKCFL
YQLSQKTGLQYFKNVVLVASPQDRYVPFHSARIEMCKTALKDRHTGPVYAEMIDNLLRPL
VDAKDCTLVRHNVFHALPNTANALIGRAAHIAVLDSELFLEKFF---LVA-GLSYFK---
---------

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-----------------------------MFI----FYQAKEKFKKELKIEGFLYSDLSV
LASDIPYFPPEEEEENLE

PF05057 // ENSGT00390000007885_1_Domain_2 (1459, 1657)

DGIHLVVCVHGLDGNSADLRLVKTFIELGLPGGKLDFLMSEK
NQ-MDTFADFDTMTDRLLDEIIQHIQLYNLS-ISRI--SFIGHSLGNII-IRSVLTRPRF
RYYLNKLHTFLSLSGPHLGTLYNNSTLVSTGLWLMQKLKKSGSLLQLTFRDNADLRKCFL
YQLSQKTGLQYFKNVVLVASPQDRYVPFHSARIEMCKTALKDRHTGPVYAEMINNLLGPL
VEAKDCTLIRHNVFHALPNTANTLIGRAAHIAVLDSELFLEKFF---LVA-GLNYFK---
---------

MSEIQGTVEFSVELHKFYNVDLFQRGYYQIRVTLKVSSRIPHRLSASIAGQTESS----S
LHSACVHDSTVHSRVFQILYRNEEVPINDAVVFRVHLLLGGERMEDALSEVDFQ

PF12394 // ENSGT00390000007885_1_Domain_0 (115, 177)

LKVDLH
FTDSEQQ-LRDVAGAPMVSSRTLGLHFHPRNGLHHQVPVMFDYFHLSVISVTVHAALVAL
QQPLISFTRPGRGSWLGKGGPDTGQEQSIISLENLVFGAGYCKPTSS-EGSFYITSENCM
QHAHKWHRDLCLLLLHAYRGLRLHFLVIMRDIPELPHTEL-EALAVEETLSQLCSELQML
NNPEKIAE--QISKDLAWLTS-HMMALWTQFLDTVTLHSQVTTYLTQEHHTLRVRRFSEA
F--FYMEHQKLAVLTFQENLIQTHSQLSLDIRNSEYLTSMPPLPAECLDIDGDWNTLPVI
FEDRYVDCPAT-GH--NL-------SVYP--NFDVPVT--SPTIMNLK------------
------------E-K----ED--NCMVNGNLSF--REDLV-LST--IKP--SQMD-----
---------------SDEEVIKCPELAENVAT-------QKHMDVCS---E---------
S-QVYITIGEFQNKTG-VP-------EDEC------------------------------
--------------WTGQTSDAGTHPMAD--------VDTSRRS---PGP----------
---------EDGQAPVLTYIDVKSSNKNPSRA-----EPLVAFNAQHENRSSRDKYGLDR
TGPSKVVVG--------GSHQNAISSDKTTLY--ELS---T--LGKGIDQEGK-------
----MVLLSLKLTP---SEPCDT-LNSTVREPLDIRSSLKDSHTEEQEELSVLSGVIKRS
SSIISDSGIESEPSSVAWSEARSRALELPSDREVLHPFVRRHALHRNSLEGGHTESNTSL
PSGIQASLTSISSLPFEEDEREVA-LTKLTKSVSAPHISSPEEAAEDADTKQQGGSFAEP
SDMHSKS------QGSPGPRSQ-LSGDSG-----------------TQDA-GEDHPLVE-
-IVLDAD----NQQGPGYIDIPKGKGKQFDDQGHC-----------------LPDGRTEN
T--PGVET----KGLNL-KIPRVIALENPRTRSLP---RALVETPKGIPKDL--NVGQPA
LSNSG--ISEVEGLSQ--HQV--PE---L-SYTSAA-----DAINMNSTGQQSQSSSPCI
MDDTAFN-R---------GVNAFPEAKHKAG----TVCPT------VTHSIHSQVLKNQE
LKAGTSIMGSHLTSAETFTLDSLKAVEVVNLSVSCTATCLPFSSVPKETPARAGFSSKQT
LFPITHQPLGSFGVVSTHSSTLDEEVSERMFS----FYQAKEKFKKELKIEGFLYSDLTV
LASDIPYFPPEEEEENLE

PF05057 // ENSGT00390000007885_1_Domain_2 (1459, 1657)

DGIHLVVCVHGLDGNSADLRLVKTFIELGLPGGKLDFLMSEK
NQ-MDTFADFDTMTDRLLDEIIQHIQLYNLS-ISRI--SFIGHSLGNII-IRSVLTRPRF
RYYLNKLHTFLSLSGPHLGTLYNNSTLVSTGLWLMQKLKKSGSLLQLTFRDNADLRKCFL
YQLSQKTGLQYFKNVVLVASPQDRYVPFHSARIEMCKTALKDRHTGPVYAEMINNLLGPL
VEAKDCTLIRHNVFHALPNTANTLIGRAAHIAVLDSELFLEKFF---LVA-GLNYFK---
---------

MSEVQGTVEFSVELHKFYNVDLFQRGYYQIRVTLKVSSRIPHRLSASIVGQSESS----S
LHSACVHESAVHSRIFQILYRNEEVPINDAMLFRTHLLLDGERVEDALSEVEFQ

PF12394 // ENSGT00390000007885_1_Domain_0 (115, 177)

LKVDLH
FTDSEQQ-LRDVSGTPMISSRTLGLHFHPQRGLHHQVPVMFDYFHLSVISVTIHAALVAL
QQPLISFTRPGRGSWLGKGGPDTGPEQPIISLENLVFGAGYCKPTSS-EGSFYVPSENCI
QHAHKWHRDLCLLLLHAYRGLRLYFLVIMRDIPELPTMEL-EQHNRARSLNDTVLPLQML
NNPEKIAE--QISKDLAWLAS-HMMALWTQFLETVTLHSEVTTYLTQEHHALRVRRFSEA
F--FYMEHQKLAVLTFQENLIQTHSQLSLDIRNSEYLTSMPPLPAECLDIDGDWNTLPVI
FEDRYVDCPVS-EH--NL-------SVYP--NFDVPLT--SPAIMDLKGK----------
--------------------E--KNIINQKSSL--RKNLP-LST--TKA--PQLG-----
---------------SDEDVIRCPEMEENVST-------RNPVDVCS---E---------
S-QVYLTIGEFQSKAL-KP-------EDAC------------------------------
--------------WTGPRPDAVRD----------SDVDIRRRS---PGP----------
---------EDGKAPALTYIDVKSSNKNHPRA-----EPMQGFNVQHDQGSSQDSYDPVK
TLPSKAVAG--------ISQNNATSLNQKAAI--EFK-----TLERGADQEGK-------
----PMLLSLKLTP---AEPCDP-LNTAPMEPWDTTSSLQE-HSEEQEDLSVLSGIIKRS
ASIISDSGIESEPSSVAWSEARSRALELPSDREVLHQVIRRHAHHRNSLEGGHTESNTSL
PSGIQASLTSISSLPFEDEERELA-LTMLTKSVSAPQISSPEDTTEGADTMKSTGGFSED
LDSSSKD------TSSPGHSSH-SYGGSR-----------------VQDV-RAGHSLAD-
-IALDSE----KAQGPGYIDIPKGKENQSCPQGPC-----------------YMDDMAEN
I--PSVET----KGLNL-KVPCTIVLENSRTRSFH---RAADETTKGRHKGL--SGGKHI
VPNNS--ILDIRAVSH--HRV--PE---I-SSVPAV-----EAVNLNSTGVQNGS--SSV
NDTMTLN-R---------RHTASLEVKHEAG----TVCPT------VTHTIASQVSRNHE
LKTGTSISGSHLNSAEAFTLDSLKAVEVVNLSVSCTATCLPFSSVPKETPARAGHSSKQS
LAPITHQPLGSFGVVSTYSSKLEEEVSERMFS----FYQAKEKFKKELKIEGFLYSDLSV
LASDIPYFPPEEEEENLE

PF05057 // ENSGT00390000007885_1_Domain_2 (1459, 1657)

DGIHLVVCVHGLDGNSADLRLVKTFIELGLPGGKLDFLMSEK
NQ-MDTFADFDTMTDRLLDEIIXXXXXXXXXXXXXXXXXFIGHSLGNII-IRSVLTRPRF
RYYLNKLHTFLSLSGPHLGTLYNNSTLVSTGLWLMQKLKKSGSLLQLTFRDNADLRKCFL
YQLSQKTGLQYFKNVVLVASPQDRYVPFHSARIEMCKTALKDRHTGPVYAEMINNLLGPL
VEAKGCTLIRHNVFHALPNTANTLIGRAAHIAVLDSELFLEKFF---LVA-GLNYFK---
---------

MSEVQGTVEFSVELHKFYNVDLFQRGYYQIRVTLKVSSRIPHRLSASIVGQTESS----S
LHSACVHDSTVHSRVFQILYRNEEVPINDAVVFRAHLLLDGERVEDALSEVDFQ

PF12394 // ENSGT00390000007885_1_Domain_0 (115, 177)

LKVDLH
FTDSEQQ-LRDVAGAAMVSSRTLGLHFHPRNGLHHQVPVMFDYFHLSVISVTVHASLVSL
QQPLISFTRPGRGSWLGKGGPDTGQEQSIISLENLVFGAGYCKPTSS-EGSFYVPSENCM
QHAHKWHRDLCLLLLHAYRGLRLYFLVMMRDIPELPHMEL-EALAVEETLSQLCSELQML
NNPEKIAE--QISKDLAWLTS-HMMALWTQFLDTVTLHSQVTTYLTQEHHTLRVRRFSEA
F--FYMEHQKLAVLTFQENLIQTHSQLSLDIRNSEYLTTMPPLPAECLDIDGDWNTLPVI
FEDRYVDCPAT-GH--NL-------SVYP--NFDVPVT--SPTIMNLK------------
------------E-K----ED--NCMVNGNLSF--REDLG-LST--IKP--SQVD-----
---------------SDEEIIRCPELAENAAT-------QNHTDVCS---D---------
S-QVYMTIGEFQSKAG-VP-------EDEC------------------------------
--------------WTSQTSDAGTYPMAD--------VDTSRRS---PGP----------
---------EDGQAPVLTYIDIKSSNKNPFRA-----EPPVAFSAQHESRSSRDKHGLDR
TGLSKVVAG--------GSHQNAISSDKTTLH--ELS---T--LGKGADQEGK-------
----MVLLGLKLIP---SEPCDP-LSSTLREPLDVRSSLKDSHTEEQEELSVLSGVIKRS
SSIISDSGIESEPSSVAWSEARSRALELPSDREVLHPFVRRHALHRNSLEGGHTESNTSL
PSGIQASLTSISSLPFEEDERELA-LTKLTKSVSAPHISSPEEAAEDIDTKQQDRGFTEP
SDMRSRS------QGSPGPCSQ-LCGDSG-----------------TQDA-GVDHPLVE-
-IVLDAD----NEQSPGYIDIPKGKGKQFDAQGDC-----------------LLDGRTEN
A--PGIET----KGLNL-KIPRVIALETPRTRSLH---RALMETPKGKPKDL--KVGQMA
LSNSG--ISEAEGISQ--HKV--PE---L-SYTSAA-----DAINLNSTGQRSQSGSPCV
MDNTAFD-R---------GVNAFPEVKHKAG----TVCPT------VTHSVHSQDLKNQE
LKAGTSIVGSHLTSAETFTLDSLKAVEVVNLSVSCTATCLPFSSVPKETPARAGFSSKQT
LFPITHQPLGSFGVVSTHSSTLDEEVRERMFS----FYQAKEKFKKELKIEGFLYSDLTV
LASDIPYFPPEEEEENLE

PF05057 // ENSGT00390000007885_1_Domain_2 (1459, 1657)

DGIHLVVCVHGLDGNSADLRLVKTFIELGLPGGKLDFLMSEK
NQ-MDTFADFDTMTDRLLDEIIQHIQLYNLS-ISRI--SFIGHSLGNII-IRSVLTRPRF
RYYLNKLHTFLSLSGPHLGTLYNSSTLVSTGLWLMQKLKKSGSLLQLTFRDNADLRKCFL
YQLSQKTGLQYFKNVVLVASPQDRYVPFHSARIEMCKTALKDRHTGPVYAEMINNLLGPL
VEAKDCTLIRHNVFHALPNTANTLIGRAAHIAVLDSELFLEKFF---LVA-GLNYFK---
---------

MCEVQGTVEFSVELQKFYNVDLFQRGYYQIRVTLKVSSRIPHRVSASIVGQTESS----S
PHSACVHESTVHSRVFQILYRNEEVSINDAVIFRAHLLLDGERVEDALSEVDFQ

PF12394 // ENSGT00390000007885_1_Domain_0 (115, 177)

LKVDLH
FTDSEQQ-LRDVAGAPMISSRTLGLHFHPRRGLHHQVPVMFDYFHLSVISVTIHAALVAL
QQPLISFTRPGRGSWLGKGGPDAGQEQSIISLENLVFGAGYCKPTSS-EGSFYVPSENCM
QRAHKWHRDLCLLLLQAYRGLRLYFLVIMKDIPELPDMDL-EVLAVEETLSQLCSELQML
NNPEKIAE--QISKDLAWLAS-HLMALWTQFLDTVTLHSQVTTYLTQEHHTLRVRRFSEA
F--FYMEHQKLAVLTFQENLMQTHSQLSLDVRNSEYLASMPPLPAECLDIDGDCNTLPVI
FEDRYVDCPVT-GH--SL-------RVYS--NFHVPGT--IPTIMDLKEKEE--------
-----------------------NHIVNRTLSC--KESFV-LSMM--KP--TQMG-----
--------------SDEEEVSRCPEPGENVTT-------QNQVDMC---LE---------
S-EVYLTIGEFQNKAG-VP-------EDEC------------------------------
--------------RTGQGFDAGTYPSAE--------MDMPRRS---LGP----------
---------EDGQTPGLTYIDVKCNNKNPHRA-----EHMELLSVHQERRSCRDKYRFER
IVPSKMAAG--------GNHQDAICPDKTALP--ELH---S--LGKGADQEGK-------
----PGLLSLKLTP---AEPSDT-PSSTLTAPLEIRSSLQDPHTEEQEELSVLSGVIKRS
SSIISDSGIESEPSSVAWSEARSRALELPSDREVLQQLARRYTLHRNSLEGEPTESNTSL
PSGIQASLTSISSLPFEEEERELA-LTKLTKSVSAPQISSPEDTAEGADTMKKERGSAKA
SDIQSKSEVSPEHSSQ-------PCGSSRTED------------------DREGHSLAE-
-EDLGA----EKHQGPGYMDIPKGKETQSDLHGSC-----------------SLDGRTES
T--PGVET----KGHDL-KIPHTIALENAKTRSVH---RGQMETPKGRPKDL--NVGKHT
LSNSS--ISEVGELSHH--KV--PE---F-SCPSAANAIH-----PNSAGQQS--SSPCL
IHDMMLN-R---------TPDSSLEVEHDAG----TVCRT------VTHSIPSHVLRNQE
PKAGTSIMGSHLTPAETFTLDSLKAVEVVNLSLSCTATCLPFSSVPKETPARAGFSSKQT
PVPITHQPLGSFGVVSAHSSKLEDEVSERMFS----FYQAKEKFKKELKIEGFLYSDLSV
LASDTPYFPPEEEEENLE

PF05057 // ENSGT00390000007885_1_Domain_2 (1459, 1657)

DGIHLVVCVHGLDGNSADLRLVKTFIELGLPGGKLDFLMSEK
NQ-MDTFADFDTMTDRLLDEIIQHIQLYNLS-ISRI--SFIGHSLGNII-IRSVLTRPRF
RYYLNKLHTFLSLSGPHLGTLYNNSTLVSTGLWLMQKLKKSGSLLQLTFRDNADLRKCFL
YQLSQKTGLQYFKNVVLVASPQDRYVPFHSARIEMCKTALKDRHAGPVYAEMINNLLGPL
MAAKDCTLIRHNVFHALPNTANTLIGRAAHIAVLDSELFLEKFF---LVA-GLNYFK---
---------

---------------------------------------------------AESS----S
LRSACVHENTVHSRVFQILYRNEEVPINDVVIFRAHLLLDGERVEDALSEVDFQLKVDLH
FTDSEQQ-LREVAGVPVISSRTLGLHFHPRRGLHHQVPVMFDYFHLSVISVTVHAALVAL
QQPLISFTRPGRGSWLGKGGPDAGPEQSSISLENLVFGAGYCKPTSS-EGSFYVPSENCM
QHAHKWHRGLCHLLLHAYHGLRAYFLVIMRDIPELPRTEL-EALAVEETLSQLCSELQML
NNPERIAE--QISKDLAWLVS-HLMALWTQFLDTVTLHSQVTTYLTQEHHTLRVRRFSEA
F--FYMEHQKLAVLTFQENLIQTHSQLSLDVRNSEYLASMPPLPAECPDIDGDWSTLPVI
FEDRYVDCPATVGH--NL-------NIYP--NFDVPVT--SPSRMNLK------------
------------H-R----EE--NHNVNSKSSF--MEDLV-LAS--RKP--PHMD-----
---------------SDEELIRGQGLGENEAT-------PNHAVLCS---E---------
S-QVYLTIGEFQNKAS-LP-------EEEC------------------------------
--------------WTGQRSEVRTHPLAD--------MDMPIKS---LGP----------
---------DDGQVPALTYIDVKSSSKNPCRI-----EPMVVISAQCETGASGDSYELDR
TVLNKMAAG--------GSHQNAICSEKTPLH--ELS---P--LGKRVEQEGK-------
----MVLLSLKPIP---SEPCDP-LSSILRDPLDIRSSLKDPHTEEQEEVLVLSGVIKRS
SSIISDSGIESEPSSVAWSDARSRALDLPSDREVLHQLVRRHALHRNSLEGGHTESNTSL
PSGIQASLTSISSLPFEEEERELA-LTKLTKSVSAPQISSPEESAEDTDTMQQGGGLAEA
LDVHTKS------IDSPGNCSQ-LCGGTR-----------------THDA-EIDHSLVE-
-IVLDAD----DHQDPGYIDIPKGKESQLDPQGHC-----------------SPGGRTDN
P--PDVDT----KGLNL-KIPRIIALEKPRDRSFH---RTVLETPKGMPKDL--SVGERA
LSDST--ISDVEDIVH--HKV--PV---W-SCALAT-----DAIDLDPTGDPS--SLPRI
TDDTAFT-K---------GANASPGTEHKAG----TMCPT------VNHSTHFQESENQE
LKAGTSITVSPLNAPETFPLDSLKAVEVVNLSVSCTATCLPFSSVLKETPARAGFSSKQT
PFPITHQPLGSFGVVSTHASRLEGEVSERMFS----FYQAKEKFKKELKIEGFLYSDLSV
LASDVPYFPPEEEEEN

PF07819 // ENSGT00390000007885_1_Domain_2 (1457, 1700)

LEDGIHLVVCVHGLDGNSADLRLVKTFIELGLPGGKLDFLMSEK
NQ-MDTFADFDTMTDRLLDEIIQHIQLYNLS-ISRI--SFIGHSLGNII-IRSVLTRPRF
RYYLNKLHTFLSLSGPHLGTLYNNSTLVSTGLWLMQKLKKSGSLLQLTFRDHADLRKCFL
YQLSQKTGLQYFKNVVLVASPQDRYVPFHSARIEMCKTALKDRHTGPVYAEMINNLLRPL
VEAKDCTLIRHNVFHALPNTANTLIGRAAHIAVLDSELFLEKFF---LVA-GLNYFK---
---------

MSEVQGTVEFSVELHKFYNVDLFQRGYYQIRVTLKVSSRIPHRLSASIAGQTESS----S
LRSAFVHDSTLHSRVFQILYRNEEVPINDAVIFQAHLLLDGERVEDALSEVDFQ

PF12394 // ENSGT00390000007885_1_Domain_0 (115, 177)

LKVDLH
FTESEQQ-LRDVAGAPVISSRMLGLHFHPRKGLHHQVPVMFDYFHLSVISVTIHAVLVAL
RQPLISFTRPGRGSWLSRGGPDMGQEQSIISLENLVFGAGYCKPTSS-EGSFYVPSENCM
QHAHKWHRDLCLLLLRAYRGLRLYFLVIMRDIPELPHMEL-EALAVEETLSQLCSELQML
NSPEKIAE--QISKDLAWLAA-HLMALWTQFLDTVTLHSHVTTYLTQEHHTLRVRRFSEA
F--FYMEHQKLAVLTFQENLTQSHSQLSLDIRNSEYLTSMPPLPAECLDIDGDWSTLPVI
FEDRYVDCPGT-GH--NL-------SVYP--NFDVSAT--SPTIRNLE------------
------------K-K----EE--NHIVNRKVPF--RDDLV-LST--VKP--AQMD-----
---------------SHEEVIRRPEPDENVTT-------QNHVDVCS---E---------
S-QVYLTIGEFQDKAG-TH-------EVES------------------------------
--------------GTGHRADVGTCPLAD--------TDMSRRS---PGP----------
---------EDGQAPALTYIDVKSSNKNVHRA-----EPMVVVSAQHESRSSRDKCGSDR
TGLSKVVAG--------ENHQNAISSEKTVLR--ELS---S--LGKGAEQETK-------
----MVLLRLKLIA---SEPCGP-LSSTLREPLDSRSSLKDPHTEEQEELSVLSGVIKRS
SSTISDSGIESEPSSVAWSEARSRALELPSDREVLHPFVRRHTLHRNSLEGGHTESNVSL
PSGIQASLTSISSLPFEEEERELA-LTKLTKSVSAPQISSPEEAANDKDTIQQGRGFAEP
SDMDLKS------KDSPGHCSH-LCLGSR-----------------IQDA-RVNHSVVE-
-VDLDAD----NQQGPGYIDIPKGKGSQCDPQGHC-----------------HLDGRTEN
T--TSVET----KGLNL-KTARIIALENTRTRSLH---RALAGAPKGMPTDF--DVDKQV
LSSDG--ISEVEGISH--NKV--PE---L-SCTSAA-----DAIKLSSTGKQSSS--PHI
VNDTAFN-R---------GGTAFSEVEHKTG----TVCPT------VTHSIHPKVLRNQE
PKAGPSIMGSPLTSAETFTLENLKTVEVVNLSVSCTATCLPFSSVPKETPARTGFSSKQT
SFPITHQPVGSFGVVSTHSSKLEEEASERMFS----FYQAKEKFKKELKIEGFLYSDLSV
LASDIPYFPPEEEEENLE

PF05057 // ENSGT00390000007885_1_Domain_2 (1459, 1657)

DGIHLVVCVHGLDGNSADLRLVKTFIELGLPGGKLDFLMSEK
NQ-MDTFADFDTMTDRLLDEIIQHIQLYNLS-ISRI--SFIGHSLGNII-IRSVLTRPRF
RYYLNKLHTFLSLSGPHLGTLYNNSALVSTGLWLMQKLKKSGSLLQLTFRDNADLRKCFL
YQLSQKTGLQYFKNVVLVASPQDRYVPFHSARIEMCKTALKDRHTGPVYAEMINNLLGPL
VEAKDCTLIRHNVFHALPNTANTLIGRAAHIAVLDSELFLEKFF---LVA-GLNYFK---
---------

MSEVQGTVEFSVELHKFYNVDLFQRGYYQIRVTLKVSSRIPHRLSASVVGQSENS----S
LHSACVHESTLHSRVFQILYRNEEVPINDAVIFRAQLLLDGERVEDALSEVEFQ

PF12394 // ENSGT00390000007885_1_Domain_0 (115, 177)

LKVDLH
FTDSEQQ-LRAVTGTPTISSRTLGLHFHPRRGLHHQVPVMFDYFHLSVISMAVHAALVAL
QQPLISFARPGRGSWLGKGGPDTGPEQPLISLENLVFGAGYCKPTSS-EGSFYAPSETCI
QHAHKWHRDLCLLLLHAYRGLRLYFLVVTRDIPELPHVEL-EALAVEETLSQLCSELQVI
T-------------TLAWV-----------------------------------------
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MSEIQGTVEFSVELHKFYNVDLFQRGYYQIRVTLKVSSRIPHRLSASIAGQTESS----S
LNSACVHDSTVHSRVFQILYRNEEVPINDAVVFRVHLLLGCERMEDALSEVDFQ

PF12394 // ENSGT00390000007885_1_Domain_0 (115, 177)

LKVDLH
FTDSEQQ-LRDVAGAPMVSSRTLGLHFHPRNGLHHQVPVMFDYFHLSVISVTVHAALVAL
QQPLISFTRPGRGSWLGKGGPDTGQEQSIISLENLVFGAVYCKPTSS-EGSFYITSENCM
QHAHKWHRDLCLLLLHAYQGLRLHFLVIMRDIPELPHMEL-EALAVEETLSQLCSELQML
NNPEKIAE--QISKDLAWLTS-HMMALWTQFLDTVTLHSQVTTYLTQEHHTLRVRRFSEA
F--FYMEHQKLAVLTFQENLIQTHSQLSLDVRNSEYLTSMPPLPAECLDIDGDWNTLPVI
FEDRYVDCPAT-GH--NL-------SVYP--NFDVPVT--SPTIMNLK------------
------------D-K----ED--NCMVNSNLSF--REDLV-LST--IKP--SQMD-----
---------------SDEEVIRCPEPAENVAT-------QNHMDVCS---E---------
S-QVYISIGEFQNKAV-VP-------EDEC------------------------------
--------------WTGQTSDAGTYPMAD--------VDTSRRS---PGP----------
---------EDGQAPVLTYIDVKSSNKNPSRA-----EPLVAFSAQHESRSSRDKYGSDR
TGLSKVVVG--------GSHQNAISSDKTTLH--ELS---T--LGKGIDQEGK-------
----MVLLSLKFTP---SEPCDP-LSSTLREPLDIRSSLKDSHTEEQEELSVLSGVIKRS
SSIISDSGIESEPSSVAWSEARSRALELPSDREVLHPCVRRHALHRNSLEGGHTESNTSL
PSGIQASLTSISSLPFEEDEREVA-LTKLTKSVSAPHISSPEESAEDADTKQQDGGFAEP
SDMHSKS------QGSPGSCSQ-LCGDSG-----------------TQDA-GADHPLVE-
-IVLDAD----NQQGPGYIDIPKGKGKQSDAQGHC-----------------LPDGRTEN
T--PGVET----KGLNL-KIPHVIAFENPRTRSLH---RALVETPKGMPKDL--NVGQPA
LSNSG--ISEVEGLSQ--HQV--PE---L-SCTSAA-----DAINVNPTGQQSQSGSPCI
MDDTAFN-R---------GMNAFPEAKHKAG----TVCPT------VTHSVHSQVLKNQE
LKAGTSIMGSHLTSAETFSVDSLKAVEVVNLSVSCTATCLPFSSVPKETPARAGFSSKQT
LFPITHQPLGSFGVVSTHSSTLDEEVSERMFS----FYQAKEKFKKELKIEGFLYSDLTV
LASDIPYFPPEEEEENLE

PF05057 // ENSGT00390000007885_1_Domain_2 (1459, 1657)

DGIHLVVCVHGLDGNSADLRLVKTFIELGLPGGKLDFLMSEK
NQ-MDTFADFDTMTDRLLDEIIQHIQLYNLS-ISRI--SFIGHSLGNII-IRSVLTRPRF
RYYLNKLHTFLSLSGPHLGTLYNNSTLVSTGLWLMQKLKKSGSLLQLTFRDNADLRKCFL
YQLSQKTGLQYFKNVVLVASPQDRYVPFHSARIEMCKTALKDRHTGPVYAEMINNLLGPL
VEAKDCTLIRHNVFHALPNTANTLIGRAAHIAVLDSELFLEKFF---LVA-GLNYFK---
---------

MSEVQGTVEFSVELHKFHNVDLFQRGYYQVRVSLKLPARIPHRLVASVGGKTEDS----G
PSSASVHESSVHSRIFQILYRNEEIAVNETMHFRAHLLLDGERVEEALSEVDFQ

PF12394 // ENSGT00390000007885_1_Domain_0 (115, 178)

LKLDLH
FTDSEHQ-LREGVGVPAISSRTLGLHLHPRRGLHHYVPIMFDYFHLSLVSLTVHASL

ENSGT00390000007885_1_Linker_0_1 (178, 326)

VAL
CQPLISSPGPGKGSWLGKGGAEAGPEQSGMSLESLVFGAGYCKPAASENGCQCQNSQLMV
QDHCHFHHALCIRLLGAHKGLQSYFSSIMKAVPALEQSSL-EEIAVEETLSQLCAEIQRV
NDPERLAE--QIGRDLAWLCS-RLL

PF12394 // ENSGT00390000007885_1_Domain_1 (326, 381)

ALWTQLLAAVSLQPAVTAHLTQEHHTLRVRRFSEA
F--FYTEHEKLAALTFQESL

ENSGT00390000007885_1_Linker_1_2 (381, 1464)

IQSQSQVSMDLRSSEYLTSMPPLPVECLDIDGDWNTLPVI
FEDRYVDCPQR-GL--LGWKPEQAARLKACRHLDEEVLLAGSVGPTLG---------ERI
LEPR------ELGFCCSRQGKTEVLWVSLTSSGEGLEEHF-NLT--EQG--IS-------
LERVRVSKS-----YSSHA----------VSL-HRTQPVRIALSMCALRRT---------
S-TYHSFIGTYQTRTPLH--------TANSNQVQSVCTAQIQYASHTVSKHKASMHCIPR
TLSTHCAQSLHTIQSQGPPPQPVLQVVSTHS-------LLFLFP---LGPSLDVL---PR
I--NAPVMKDESQ--------------VTHVASQ---AEELAICTQATGRAG-FR-EEST
TALDQREEG----RT--PADQPRIFQDA-DVQ--EFT------V-RDSDQRTDPQA----
--C-QMISEMQSAG-ESPAGPGPQLADTGRSPEEEPASQGGSWDANREEFSLPSSSIKRS
SSLISDSGIESEPSSAAWSDARSRMLGTPGDREALPQLARRRGAHRNSLEGACTDSNVSL
PSGTQASLTSISSLPFEEEERDVA-VAKLTKSVSAPQISSPEEPAEDPEEIESGGETPGA
AGVWQQGEA--------GRTGF-PCGPARLPA----------------AWAGANFEMADH
QGDVDPD----DPESGGPIDILQVRGLQCPPEGPG--------HSDRIE----------S
AAHRACVVGPGAQGLSL-EALNASSWSGSEAGRLGDHGQDPTEARDIVPAD--WPLGRVD
FPNPG--IADTVDFSH-------------------------------WDGQQS--SENPT
EDTAIGMGE---------GVEALQEIELGESPVANEAIALPDTDSQDQWAVAHPGPDYQD
PKHPSNSNGIHCAPGETLTPGGRRAPEVANLSLSCTATCLPFSSTLTEVPAAAGFVAKQA
PFPITHQPLGSFGAVSCNAGSPAEDINERMCS----FYQAKEKFKTELKIEGSLYSDLSV
LASDIPYFPPEEEEENLEEGIHL

PF07819 // ENSGT00390000007885_1_Domain_2 (1464, 1585)

VVCVHGLDGNSSDLRLVKTFIELGLPGGKLDFLMSER
NQ-TDTFSDFDTMTDRLLDEIIQHIQLYSLS-ISRI--SFIGHSLGNII-VRSVLTRPRF
RCYLSKLHTFLSLSGPHLGTLFNNSTLVSTGLWLMQKLKKSGSLLQLTFRDHTDLRKCFL
YQLSQKTGLQYFKNVVLVASPQDRYVPFHSARIEMCRTALRDRHTGPVYAEMIHNLLQPL
VEAK-CTLVRLTVFHSLPSTA-TLIGRAAHIAVLDSEALPGEVPLDSLVA-GLNYFK---
---------

MSEVQGTVEFSVELHKFYNVDLFQRGYYQIRVTLKVSSRIPHRLSASIVGQTESS----S
LHSACVHDSTVHSRVFQILYRNEEVPINDAVVFRAHLLLDGERVEDALSEVDFQ

PF12394 // ENSGT00390000007885_1_Domain_0 (115, 177)

LKVDLH
FTDSEQQ-LRDVAGAPMVSSRALGLHFHPRNGLHHQVPVMFDYFHLSVISVTIHASLVAL
QQPLISFTRPGRGSWLGKGGPDTGQEQSIISLENLVFGAGYCKPTSS-EGSFYVPSENCM
QHAHKWHRDLCLLLLHAYRGLRLYFLVMMRDIPELPHMDL-EALAVEETLSQLCSELQML
NNPEKIAE--QISKDLAWLTS-HMMALWTQFLDTVTLQSQVTTYLTQEHHTLRVRRFSEA
F--FYMEHQKHAVLTFQENLIQTHSQLSLDIRNSEYLTSMPPLPAECLDIDGDWNTLPVI
FEDRYVDCPAT-GH--NL-------SVYP--NFDVPVT--SPTIMNLK------------
------------E-K----ED--NCMVNSNLSF--REDLG-LSA--IKP--SQVD-----
---------------SDEEVTRCPELAENAAT-------QNHTDMCS---D---------
F-QVYMTIGEFQSKAG-VP-------EDEC------------------------------
--------------WTSQTSDAGTYPMAD--------VDTSRRS---PGP----------
---------EDEQAPVLTYIDIKSSNKNPSRA-----EPPVAFNAQHENRSSRDKHGLDR
TGLSKVVAG--------GSHPNTISSDKTALH--ELS---T--LGKGADQEGK-------
----MVLLGLKLIP---SEPCDP-LSSTLREPLDVRSSLKDSHTEEQEELSVLSGVIKRS
SSIISDSGIESEPSSVAWSEARSRALELPSDREVLHPFVRRHALHRNSLEGGHTESNTSL
PSGIQASLTSISSLPFEEDERELA-LTKLTKSVSAPHISSPEEAAEDIDTKQQDRGFAEP
SDVHSRS------QGSPGPCSQ-LCGDSG-----------------TQDT-GVDHPLVE-
-IVLDAD----NEQSPGDKDSPKGKGKQFEAQGDC-----------------LLDGRTEN
T--PGIET----KGLNL-KIPRVIALETPRTRSLH---RALMETPKGKPKDL--KMGQTA
LSNSG--ISEAEGISQ--HKV--PE---L-SHTSAA-----DATNLNSTGQRSQSGSPCV
MDNTAFD-R---------GVTAFPEVKHKAG----PVCPT------VTHSVHSQVLKNQE
LKAGTSITGSHLTSAETFTLDSLKAVEVVNLSVSCTATCLPFSSVPNETPARAGFSSKQT
LFPITHQPLGSFGVVSTHSSTLDEEVRERMFS----FYQAKEKFKKELKIEGFLYSDLTV
LASDIPYFPPEEEEENLE

PF05057 // ENSGT00390000007885_1_Domain_2 (1459, 1657)

DGIHLVVCVHGLDGNSADLRLVKTFIELGLPGGKLDFLMSEK
NQ-MDTFADFDTMTDRLLDEIIQHIQLYNLS-ISRI--SFIGHSLGNII-IRSVLTRPRF
RYYLNKLHTFLSLSGPHLGTLYNNSTLVSTGLWLMQKLKKSGSLLQLTFRDNADLRKCFL
YQLSQKTGLQYFKNVVLVASPQDRYVPFHSARIEMCKTALKDRHTGPVYAEMINNLLGPL
VEAKDCTLIRHNVFHALPNTANTLIGRAAHIAVLDSELFLEKFF---LVA-GLNYFK---
---------

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-------MLDVESFTY--PRV--PE---V-SCAPAA-----KTIDVDSAGEQSS--SLGI
TEDTAPS-R---------GADTFPEDEREAG----A-GST------VTLSVPSQVTGNQE
PRAGTTILLSHMTSAESSSLDSLKAVEVVNLSVSCAATCLPFSSVPKETPARAGFSSKQT
PFPITHQPLGSFGVIPNHSRKLEEEVSERMFSVFSSFYQAKEKFKKELKIDGFLYSDLSV
LASDIPYFPPEEEEENLE

PF05057 // ENSGT00390000007885_1_Domain_2 (1459, 1657)

DGIHLVVCVHGLDGNSADLRLVKTFIELGLPGGKLDFLMSEK
NQ-MDTFADFDTMTDRLLDEIIQHIQLYNLS-ISRI--SFIGHSLGNII-IRSVLTRPRF
RYYLNKLHTFLSLSGPHLGTLYNNSALVSTGLWLMQKLKKSGSLLQLTFRDNADLRKCFL
YQLSQKTGLQYFKNVVLVASPQDRYVPFHSARIEMCKTALRDRHTGPVYAEMINNLLRPL
VDAKDCTLIRHNVFHALPNTANTLIGRAAHIAVLDSELFLEKFF---LVA-GLNYFK---
---------

MCEVQGTVEFSVELHKFYNVDLFQRGYYQIRVTLKVSSRIPHRLSASIVGQTESS----S
LHSACVHEGTVHSRVFQILYRNEEVPINDAVIFRAHLLLDGERVEDALSEVDFQ

PF12394 // ENSGT00390000007885_1_Domain_0 (115, 177)

LKVDLH
FTDSEQQ-LRDVVGAPMISSRTLGLHFHPRRGLHHQVPVMFDYFHLSVISVTIHAALVAL
QQPLISFTRPGRGSWLGKGGPDTGQEQSIISLENLVFGAGYCKPTSS-EGSFYVPSENCM
QHAHKWHRDLCLLLLQAYQGLRLYFLVIMRDIPELPHMDL-EALAVEETLSQLCSELQML
NNPEKIAE--QISKDLAWLAS-HLTALWTQFLDTVTLHSRVTTYLTQEHHNLRVRRFSEA
F--FYMEHQKLAVLTFQENLMQSHSQLSLDVRNSEYLTSMPPLPAECLDIDGDWNTLPVI
FEDRYVDCPVT-GH--NL-------SVYP--NFDGPAT--IPTIMNLKEKKE--------
-----------------------NRTVNGTSSL--KEGLV-LSTM--KP--AQMD-----
--------------PDEEEVSRCPEPGENVTT-------QNRVDMC---FE---------
S-EVYLTIGEFQNKAG-VA-------EDEC------------------------------
--------------WTGQKSDAGTYPLAE--------VDVPR-S---MGP----------
---------NDAHAPVLTYIDVKSSNKNPHRP-----EPIELLSGHHETRSSRDKCGFER
--PSKMVAG--------GTHQDSISPDKLALT--ELS---T--VGKGTDQEGK-------
----PGLLSLKLTH---AKPCDH-LSYTLRAPLDVKSSLQDSHTEEQEELSVLSGVIKRS
SSIISDSGIESEPSSVAWSEARSRALELPSDREVLYHLAQRYAVHRNSLEGGHTESNTSL
PSGIQASLTSISSLPFEEEERELA-LTKLTKSVSAPQISSPEETAESADLVNKQGGSAEA
SDMHSKSKVSPAHSSQ-------PCDGSRTKD------------------DGEDHSLVE-
-VDLDA----EKRQGPGYMDIPKGKETWLVAQGSC-----------------PLDGRTES
T--TGVET----KGLHL-KIPRTITLENAKTRSFH---GGQMETTKGRLKDL--NVGRLI
LSNSS--ISEDGEMSHH--KV--PE---F-SCPSAANTTQ-----PNSADQQS--SSPCL
IEGTMLN-R---------GPDTSLEVEHEAG----TVCPT------VTHSISSHVLRNQE
PKAGTSIMGSHLNPTETFTLDSLKAVEVVNLSLSCTATCLPFSSVPKETPARAGFSSKQT
PVPITHQPLGSFGVVSTHSSKLEEEVSERMFS----FYQAKEKFKKELKIEGFLYSDLSV
LASDTPYFPPEENEENLE

PF05057 // ENSGT00390000007885_1_Domain_2 (1459, 1657)

DGIHLVVCVHGLDGNSADLRLVKTFIELGLPGGKLDFLMSEK
NQ-MDTFADFDTMTDRLLDEIIQHIQLYNLS-ISRI--SFIGHSLGNII-IRSVLTRPRF
RYYLNKLHTFLSLSGPHLGTLYSNSTLVSTGLWLMQKLKKSGSLLQLTFRDNADLRKCFL
YQLSQKTGLQYFKNVVLVASPQDRYVPFHSARIEMCKTALKDRHTGPVYAEMINNLLGPL
VAAKDCTLIRHNVFHALPNTANTLIGRAAHIAVLDSELFLEKFF---LVA-GLNYFK---
---------

MSEVQGTVEFSVELHKFYNVDLFQRGYYQIRVTLKVSSRIPHRLSASIVGQTDSS----S
LHSACVHESTVHSRIFQILYRNEEVPINDAVIFRAHLLLDGERVEETLSEVDFQ

PF12394 // ENSGT00390000007885_1_Domain_0 (115, 178)

LKVDLH
FTDSEQQ-LRDVAGAPMISSRTLCLHFHPRKGLHHQVPVMFDYFHLSVISVTIHAAL

ENSGT00390000007885_1_Linker_0_1 (178, 323)

VAL
QQPLISFTRPGRGSWLGKAGPDTGPEPSSLSLENLVFGAGYCKPASS-EGSFYVPSENCM
QHAYKWHRELCFLLLHAYRGLHAYFLVIMKDIPELPHMEL-ESLAVEETLSQLCSELQML
NNPEKIAE--QISKDLAWLAS-

PF12394 // ENSGT00390000007885_1_Domain_1 (323, 381)

HLMALWTQFLDTVTLHSQVTTYLTQEHHTLRVRRFSEA
F--FYMEHQKLSVLTFQENL

ENSGT00390000007885_1_Linker_1_2 (381, 1459)

TQTHSQLSLDVRNSEYLTTMPPLPAECLDIDGDWNTLPVI
FEDRYVDCPVT-GH--NL-------SVYP--NFDVPVT--SPAIMNLK------------
------------D-R----EE--NHLVNRKSSF--REDLV-LPT--MKP--HQMD-----
---------------SDEEVIRCPEPDENVTT-------PNHVDVCS---E---------
S-QVYLTIGEFQNKAG-LP-------EDEC------------------------------
--------------WTGQKSDVGMLPLAD--------EDL-PRS---PGP----------
---------EDGQAPALTYIDVKSSNKNPCRA-----EPTVARSAKHESGHSQDNHEIDR
AVLSKGVAG--------GSHQNAISSQKTALH--ELG---T--LGKGTDQESK-------
----MVLLNLKLIP---SEPCDP-LSSTLRDPLDIRASPKDPHTEEQDEVSVLSGVIKRS
SSIISDSGIESEPSSVAWSEVRSRALDLPSDREVLHQLVRRHALHRNSLEGGHTESNTSL
PSGIQASLTSISSLPFEEEERELA-LTKLTKSVSAPQISSPEESAEDIDTMQQDGGLAET
SAVHIKS------IDPPGHGSQ-LSGGSR-----------------IQDT-GVNHSLVE-
-VVSDAN----NPQGPGYIDIPKGKESQLDPQGPC-----------------CRDGRTEN
P--PGVET----TGLNL-KIPRVIAVENPRNRSFS---RPLMETPKGMPKDL--NKGKGA
LSNSN--ISDVESISH--HKV--SE---L-SRTSDA-----EPTSLDSTGEQSSS--PCI
IDDTAFS-R---------RTNSFLEVGHEAG----TVCST------VTHTIPSQVLGNQE
PQAGTSVMASHLTPTETFTLESLKAVEVVNLSVSCTATCLPFSSVPKEPPARAGFSSKQT
PFPITHQPMGSFGVVSTHSSKLEEEISERMFS----FYQAKEKFKKELKIDGFLYSDLSV
LASDIPYFPPEEEEENLE

PF05057 // ENSGT00390000007885_1_Domain_2 (1459, 1657)

DGIHLVVCVHGLDGNSADLRLVKTFIELGLPGGKLDFLMSEK
NQ-MDTFADFDTMTDRLLDEIIQHIQLYNLS-ISRI--SFIGHSLGNII-IRSVLTRPRF
RYYLNKLHTFLSLSGPHLGTLYNNSTLVSTGLWLMQKLKKSGSLLQLTFRDNADLRKCFL
YQLSQKTGLQYFKNVVLVASPQDRYVPFHSARIEMCKTALKDRHTGPVYAEMINNLLRPL
VEAKDCTLIRHNVFHALPNTANTLIGRAAHIAVLDSELFLEKFF---LVA-GLNYFK---
---------

MCEVQGTVEFAVELHKFYNVDLFQRGYYQIRVTLKISSRIPHRVSASIVGQTESS----S
LHSACVHESTVHSRVFQILYRNEEVPINDAVIFRAHLLLDGERVEDALSEVDFQ

PF12394 // ENSGT00390000007885_1_Domain_0 (115, 177)

LKVDLH
FTDSEQQ-LRDVPGAPLISSRTLGLHFHPQRGLHHQVPVMFDYFHLSVISVTIHASLVAL
QQPLISFTRPGRGSWLGKAGPDAGQDQSIISLENLVFGAGYCKPTSS-EGSFYVPSENCM
QHAHKWHRDLCLLLLQAYRGLRLYFLIIMRDVPELPHMDL-EALAVEETLSQLCSELQVS
SPQRSSPR--------RWCGS-L-------------------------------------
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---------

MSEVQGTVEFSVELHKFYNVDLFQRGYYQIRMTLKASSRVPHRLS-SVAGQTDGS----S
LHSACVHESTVHSRIFQILYRNEEVPISDAAIFRAHLLLDGERVEEALSEVGFQLKVDLH
FTDSKQQ-LRDGAGAPMISSRTLGLHFQPRRGLHHHVPVMFDYFHLSVISVTVHAALVAL
QQPLISFTRPGRGSWLGKGGVGAGPEQSSLSLENLVFGAGYCKPTSS-EGSFYASSESCM
QHAYKWHRELCFLLLHAHRGLRAYFLVIMRDVPELPHVEL-ESLAVEETLSQLCSELQXX
XXXXXXXX--XXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVRRFSEA
F--FYMEHQKLAVLTFQEN-------------------------------------LPVI
FESRYVDCPAT-GH--NL-------SVYP--DFDVPAT--SPAKRSLKDR----------
-------------------EE--ECIVNRKSPF--RENLA-LPT--MKA--PQPD-----
---------------SDEVGTRCPKPDEAVTA-------PGHTDTCS---E---------
S-QVCLTVGEFQDKAG-LP-------EDAW------------------------------
--------------QAGPGSDVGMHSLAY--------GDPPGRS---PGP----------
---------EGGQDPAWTDADVRSSGNIPCSA-----DPAMATGAWHESGHFGDTCEPDG
APLREGVAG--------GGQQNAIASEKTAPHESQ-------MLGHGAGREGK-------
----AALLSLKLHP---GEPDEP-PGSALGDSWDVRASPKDPRTEGREELALLSGLIKRS
SSVISDSGIESEPSSVAWSEARSRALELPSDRDAVHQLVRRHALHRASLGGGHTESSTSL
PSGAQASLTSISSLPFEEEGREVE-LTKLTKSVSAPQISSPEESAEDVGAVRPVGGLAEA
AAVHGKG------ADPPGPCLR-LGGGSG-----------------IQDA-GVDCPPPD-
-VVXXXX---XXXXXXXXXXXXXXXXXXXXXXXXX-----------------XXXXXXXX
X---XXXX-----XXXX-XXXXXXXXXXXXXXXXX---XXXXXXXXXXXXXXXXGVGEGA
VSDSS--SSDV-------TSL--AG---P-GCTSAP-----DAIGPDAAGQRSVS-----
-GDR--AFR---------GASPFPEVGHGAG----SVCST------AAHASPSQVSGSQE
PRAGTSVMASQLAPAETCTPDSLRAVAIVNLSVSCTATCLPFSSVPKETPARAGFSSKQT
PFPITHQPLGSFGVVPARPGKAEEDAGGRMFS----FYQAKEKFKKELKIDGFLYSDLSV
LASDIPYFPPEEEEEN

PF05057 // ENSGT00390000007885_1_Domain_2 (1457, 1659)

LEEGIHLVVCVHGLDXXSADLRLVKTFILLGLPGGKLDFLMSEK
NQ-MDTFADFDTMTDRLLDEIIQHIQLYNLS-ISRI--SFIGHSLGNII-IRSVLTRPRF
RYYLSKLHTFLSLSGPHLGTLYNSSALVSTGLWLMQKLKKSGSLLQLAFRDHADLRKCFL
YQLSQKTGLQYFKNVVLVASPQDRYVPFHSARIEMCT-ALRDRHTGPVYAEMIHNLLSPL
VAAKGCTLVRHNVFHALPNTANALIGRAAHIAVLDSEVFLEKFF---LVA-GLNYFK---
---------

MSEIQGTVEFSVELHKFYNVDLFQRGYYQIRVTLKVSSRIPHRLSASIAGQTESS----S
LHSACVHDSTVHSRVFQILYRNEEVPINDAVVFRVHLLLGGERMEDALSEVDFQ

PF12394 // ENSGT00390000007885_1_Domain_0 (115, 177)

LKVDLH
FTDSEQQ-LRDVAGAPMVSSRTLGLHFHPRNGLHHQVPVMFDYFHLSVISVTVHAALVAL
QQPLISFTRPGRGSWLGKGGPDTGQEQSIISLENLVFGAGYCKPTSS-EGSFYITSENCM
QHAHKWHRDLCLLLLHAYRGLRLHFLVIMRDIPELPHTEL-EALAVEETLSQLCSELQML
NNPEKIAE--QISKDLAWLTS-HMMALWTQFLDTVTLHSQVTTYLTQEHHTLRVRRFSEA
F--FYMEHQKLAVLTFQENLIQTHSQLSLDIRNSEYLTSMPPLPAECLDIDGDWNTLPVI
FEDRYVDCPAT-GH--NL-------SVYP--NFDVPVT--SPTIMNLK------------
------------E-K----AD--NCMVNGNLSF--REDLV-LST--IKP--SQMD-----
---------------SDEEVIKCPELAENVAT-------QKHMDVCS---E---------
S-QVYITIGEFQNKTG-VP-------EDEC------------------------------
--------------WTGQTSDAGTHPMAD--------VDTSRRS---PGP----------
---------EDGQAPVLTYIDVKSSNKNPSRA-----EPLVAFNAQHENRSSRDKYGLDG
TGPSKVVVG--------GSHQNAISSDKTTLH--ELS---T--LGKGIDQEGK-------
----MVLLSLKLTP---SEPCDP-LNSTVREPLDIRSSLKDSHTEEQEELSVLSGVIKRS
ASIISDSGIESEPSSVAWSEARSRALELPSDREVLHPFVRRHALHRNSLEGGHTESNTSL
PSGIQASLTSISSLPFEEDEREVA-LTKLTKSVSAPHISSPEEAAEDADTKQQGGSFAEP
SDMHSKS------QGSPGPCSQ-LSGDSG-----------------TQDA-GADHPLVE-
-IVLDAD----NQQGPGYIDIPKGKGKQFDAQGHC-----------------LPDGRTEN
T--PGVET----KGLNL-KIPRVIALENPRTRSLP---RALVETPKGIPKDL--NVGQPA
LSNSG--ISEVEGLSQ--HQV--PE---L-SYTSAA-----DAINMNSTGQQSQSGSPCI
MDDTAFN-R---------GVNAFPEAKHKAG----TVCPT------VTHSVHSQVLKNQE
LKAGTSIMGSHLTSAETFTLDSLKAVEVVNLSVSCTATCLPFSSVPKETPARAGFSSKQT
LFPITHQPLGSFGVVSTHSSTLDEEVSERMFS----FYQAKEKFKKELKIEGFLYSDLTV
LASDIPYFPPEEEEENLE

PF05057 // ENSGT00390000007885_1_Domain_2 (1459, 1657)

DGIHLVVCVHGLDGNSADLRLVKTFIELGLPGGKLDFLMSEK
NQ-MDTFADFDTMTDRLLDEIIQHIQLYNLS-ISRI--SFIGHSLGNII-IRSVLTRPRF
RYYLNKLHTFLSLSGPHLGTLYNNSTLVSTGLWLMQKLKKSGSLLQLTFRDNADLRKCFL
YQLSQKTGLQYFKNVVLVASPQDRYVPFHSARIEMCKTALKDRHTGPVYAEMINNLLGPL
VEAKDCTLIRHNVFHALPNTANTLIGRAAHIAVLDSELFLEKFF---LVA-GLNYFK---
---------

MSEVQGTVEFSVELHKFYNVDLFQRGYYQIRVTLKMSTRIPHRLSASIVGQSESS----N
LHSACVHETAVHSRVFQILYRNEEVPINDAMLFRAHFLLDGERVIHQPSSY--------E
LTHLPFR-LRDVTGT

PF12394 // ENSGT00390000007885_1_Domain_0 (136, 177)

PVTSSRTLGLHFHPRRGLHHQVPVMFDYFHLSVISVTIHAALVAL
QQPLLSFTRPGRGSWLGKGGPDTGPEQPVISLENLVFGAGYCKPTSS-EGSFYVPSENCI
QHAYKWHRDLCLLLLHAYRGLRLYFLVIMRDIPELPTIEL-EALAVEETLSQLCSELQFW
DKLVFHL-----SH------------NFSQ------------------------------
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---------

MSEVQGTVEFSVELHKFYNVDLFQRGYYQIRVTLKVSSRIPHRLSASIVGQTESS----S
LHSACVHDSTVYSRVFQILYRNEEVPINDAVVFRAHLLLDGERVEDALSEVDFQ

PF12394 // ENSGT00390000007885_1_Domain_0 (115, 177)

LKVDLH
FTDSEQQ-LRDVAGAPMVSSRTLGLHFHPRNGLHHQVPVMFDYFHLSVISVTIHASLVAL
QQPLISFTRPGRGSWLGKGGPDTGQEQSIISLENLVFGAGYCKPTSS-EGSFYVPSENCM
QHAHKWHRDLCLLLLHAYRGLRLHFLVIMRDIPELPHMEL-EALAVEETLSQLCSELQML
NNPEKIAE--QISKDLAWLTS-HMMALWTQFLDTVTLHSQVTTYLTQEHHTLRVRRFSEA
F--FYMEHQKLAVLTFQENLIQTHSQLSLDIRNSEYLTSMPPLPAECLDIDGDWNTLPVI
FEDRYVDCPAT-GH--NL-------SVYP--NFDVPVT--SPTIMNLK------------
------------E-K----ED--NCMVNSNLSF--REDLG-LST--IKP--SQVD-----
---------------SDEEVIRCPEPAENTAT-------QNHTDVCS---D---------
S-QVYMTIGEFQSKAG-MP-------EDEC------------------------------
--------------WTSQTSDAGTYPMAD--------VDTSRRS---PGP----------
---------EDGQAPVLTYIDIQSSNKNPSRA-----EPSMAFNAQHESRTSRDKHRLDR
TGLSKVVAG--------GSHQNAISSDKTTLH--ELN---T--LGRGADQEGK-------
----VVLLGLKLIP---SDPCDP-LSSTLREPLDVRSSLKDSHTEEQEELSVLSGVIKRS
SSIISDSGIESEPSSVAWSEARSRALELPSDREVLHPFVRRHALHRNSLEGGHTESNTSL
PSGIQASLTSISSLPFEEDERELA-LTKLTKSVSAPHISSPEEAAEDIVTKQQDRGFAEP
SDMHSGS------HGSPGPCSQ-LCGDSG-----------------TQDA-GVDHPLVE-
-IVLDAD----NEQSPGYIDIPKGKGKQFDAQGDC-----------------LLDGRTEN
T--PGIET----KGLNL-KIPRVIALETPRTRSLH---RTLMETPKGKPKDL--KVGQTA
LSNSG--ISETEGISQ--HKL--PE---L-SYTSVA-----DAINLNSTGQRSQSGSPCV
MDNTAFD-R---------GVNAFPEFEHKAG----TVCPT------VTHSVHSQVLKNQE
LKAGTSIMGSHLTSAETFTLDSLKAVEVVNLSVSCTATCLPFSSVPKETPARAGFSSKQT
LFPITHQPLGSFGVVSTHSSTLDEEVRERMFS----FYQAKEKFKKELKIEGFLYSDLTV
LASDIPYFPPEEEEENLE

PF05057 // ENSGT00390000007885_1_Domain_2 (1459, 1657)

DGIHLVVCVHGLDGNSADLRLVKTFIELGLPGGKLDFLMSEK
NQ-MDTFADFDTMTDRLLDEIIQHIQLYNLS-ISRI--SFIGHSLGNII-IRSVLTRPRF
RYYLNKLHTFLSLSGPHLGTLYNNSTLVSTGLWLMQKLKKSGSLLQLTFRDNADLRKCFL
YQLSQKTGLQYFKNVVLVASPQDRYVPFHSARIEMCKTALKDRHTGPVYAEMINNLLGPL
VEAKDCTLIRHNVFHALPNTANTLIGRAAHIAVLDSELFLEKFF---LVA-GLNYFK---
---------

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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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-----------------------------------SFYQAKEKFKKELKIEGFLYSDLSV
LASDVPYFPPEEEEGDLE

PF05057 // ENSGT00390000007885_1_Domain_2 (1459, 1657)

EGIHLVVCVHGLDGNSADLRLVKTFIELGLPGGKLDFLMSEK
NQ-MDTFADFDTMTDRLLDEIIQHIQLYNLS-ISRI--SFIGHSLGNII-IRSVLTRPRF
RYYLTKLHTFLSLSGPHLGTLYSNSTLVSTGLWLMQKLKKSGSLLQLTFRDNADLRKCFL
YQLSQKTGLQYFKNVVLVASPQDRYVPFHSARIEMCKTALKDRHTGPVYAEMINNLLGPL
AEAKDCTLIRHNVFHALPNTANTLIGRAAHIAVLDSELFLEKFF---LVA-GLNYFK---
---------

MSEVQGTVEFSVELHKFYNVDLFQRGYYQIRVTLKVSSRIPHRLSASIVGQSESS----S
LHSACVHESAVHSRVFQILYRNEEVSINDAMLFRVHLLLDGERVEDALSEVEFQ

PF12394 // ENSGT00390000007885_1_Domain_0 (115, 177)

LKVDLH
FTDSEQQ-LRDVTGTPMISSRTLGLHFHPRRGLHHQVPVMFDYFHLSVISVAIHAALVAL
QQPLISFTRPGRGSWLGKGGPDTGPEQPTISLENLVFGAGYCKPTSS-EGSFYVPSENCI
QHAHKWHRDLCLLLLHAYQGLRLYFLVIMRDIPELPTMEL-EALAVEETLSQLCSELQML
NNPEKIAE--QISKDLAWLAS-HLMALWTQFLDTVTLHSQVTTYLTQEHHTLRVRRFSEA
F--FYMEHQKLAVLTFQENLIQTHSQLSLDIRNSEYLTSMPPLPAECLDIDGDWNTLPVI
FEDRYVDCPVS-GH--NL-------SVYP--NFDVPVT--SPAIMNLK------------
------------G-K----EK--N-LINQNSSS--RKDIP-LST--TEA--PQLG-----
---------------SDEDVTRRPEVQENVST-------WNPIDVCS---E---------
S-QVYLTIGEFQNRAG-IP-------EDEC------------------------------
--------------WTGPRPDAVKDSLTD--------TDICSRS---PGP----------
---------DEGQTPALTYIDVQSSNKYCPRA-----ELVQGINVQHEHRSSRESYGIVK
TVPSKVVAG--------TSQNNSTSLNQTAAL--ELR---T--LGRGVNQDGK-------
----PVLLSLKLTP---AEPCDP-PSTALREALDTKPSQP-DHAEEPEDLSALSGVIKRS
ASIISDSGIESEPSSVAWSEARSRALELPSDRDVLHQVVRRHAHHRNSLEGGHTESNTSL
PSGIQASLSSISSLPFEEEERELA-LNKLTKSVSAPQISSPEESAEGADTIKNTAGFSED
LDPSSKE------NSPPRHTSL-SYGGSR-----------------VQDV-RAGHSLAD-
-IALDSD----RPQGPGYMDIPNDKGNHPELQEPC-----------------CLDGMAET
P--LHVET----KGLNL-KIPCTIVLENSKSRSFH---RAAGETAKGKPEEL--SMSKCV
LSNNS--ISEVRAASH--HRV--PE---I-SCSPAV-----EAVNLNSTGVQNSS--LSV
NDTMTLN-R---------RHNASLEAKHEAG----TVCPT------VTHTIASQVSRNQE
LKTGTSISGSHLNSTEAFTLDSLKAVEVVNLSVSCTATCLPFSSVPKETPARAGLSSKQN
PAPITHQPLGSFGVVSTYSSKLEEEVSERMFS----FYQAKEKFKKELKIEGFLYSDLSV
LASDIPYFPPEEEEENLE

PF05057 // ENSGT00390000007885_1_Domain_2 (1459, 1657)

DGIHLVVCVHGLDGNSADLRLVKTFIELGLPGGKLDFLMSEK
NQ-TDTFADFDTMTDRLLDEIIQHIQLYNLS-ISRI--SFIGHSLGNII-IRSVLTRPRF
RYYLNKLHTFLSLSGPHLGTLYNNSTLVSTGLWLMQKLKKSGSLLQLTFRDNADLRKCFL
YQLSQKTGLQYFKNVVLVASPQDRYVPFHSARIEMCKTALKDRHTGPVYAEMINNLLGPL
VEAKDCTLIRHNVFHALPNTANTLIGRAAHIAVLDSELFLEKFF---LVA-GLNYFK---
---------

MSEIQGTVEFSVELHKFYNVDLFQRGYYQIRVTLKVSSRIPHRLSASIAGQTESS----S
LHSACVHDSTVHSRVFQILYRNEEVPINDAVVFRVHLLLGGERMEDALSEVDFQ

PF12394 // ENSGT00390000007885_1_Domain_0 (115, 177)

LKVDLH
FTDSEQQ-LRDVAGAPMVSSRTLGLHFHPRNGLHHQVPVMFDYFHLSVISVTVHAALVAL
QQPLISFTRPGRGSWLGKGGPDTGQEQSIISLENLVFGAGYCKPTSS-EGSFYITSENCM
QHAHKWHRDLCLLLLHAYRGLRLHFLVIMRDIPELPHTEL-EALAVEETLSQLCSELQML
NNPEKIAE--QISKDLAWLTS-HMMALWTQFLDTVTLHSQVTTYLTQEHHTLRVRRFSEA
F--FYMEHQKLAVLTFQENLIQTHSQLSLDIRNSEYLTSMPPLPAECLDIDGDWNTLPVI
FEDRYVDCPAT-GH--NL-------SVYP--NFDVPVT--SPTIMNLK------------
------------E-K----AD--NCMVNGNLSF--REDLV-LST--IKP--SQMD-----
---------------SDEEVIKCPELAENVAT-------QKHMDVCS---E---------
S-QVYITIGEFQNKTG-VP-------EDEC------------------------------
--------------WTGQTSDAGTHPMAD--------VDTSRRS---PGP----------
---------EDGQAPVLTYIDVKSSNKNPSRA-----EPLVAFNAQHENRSSRDKYGLDG
TGPSKVVVG--------GSHQNAISSDKTTLH--ELS---T--LGKGIDQEGK-------
----MVLLSLKLTP---SEPCDP-LNSTVREPLDIRSSLKDSHTEEQEELSVLSGVIKRS
ASIISDSGIESEPSSVAWSEARSRALELPSDREVLHPFVRRHALHRNSLEGGHTESNTSL
PSGIQASLTSISSLPFEEDEREVA-LTKLTKSVSAPHISSPEEAAEDADTKQQGGSFAEP
SDMHSKS------QGSPGPCSQ-LSGDSG-----------------TQDA-GADHPLVE-
-IVLDAD----NQQGPGYIDIPKGKGKQFDAQGHC-----------------LPDGRTEN
T--PGVET----KGLNL-KIPRVIALENPRTRSLP---RALVETPKGIPKDL--NVGQPA
LSNSG--ISEVEGLSQ--HQV--PE---L-SYTSAA-----DAINMNSTGQQSQSGSPCI
MDDTAFN-R---------GVNAFPEAKHKAG----TVCPT------VTHSVHSQVLKNQE
LKAGTSIMGSHLTSAETFTLDSLKAVEVVNLSVSCTATCLPFSSVPKETPARAGFSSKQT
LFPITHQPLGSFGVVSTHSSTLDEEVSERMFS----FYQAKEKFKKELKIEGFLYSDLTV
LASDIPYFPPEEEEENLE

PF05057 // ENSGT00390000007885_1_Domain_2 (1459, 1657)

DGIHLVVCVHGLDGNSADLRLVKTFIELGLPGGKLDFLMSEK
NQ-MDTFADFDTMTDRLLDEIIQHIQLYNLS-ISRI--SFIGHSLGNII-IRSVLTRPRF
RYYLNKLHTFLSLSGPHLGTLYNNSTLVSTGLWLMQKLKKSGSLLQLTFRDNADLRKCFL
YQLSQKTGLQYFKNVVLVASPQDRYVPFHSARIEMCKTALKDRHTGPVYAEMINNLLGPL
VEAKDCTLIRHNVFHALPNTANTLIGRAAHIAVLDSELFLEKFF---LVA-GLNYFK---
---------

MSEVQGTVEFSVELHKFYNVDLFQRGYYQIRVTLKVSSRIPHRLSASIVGQTDSG----S
LRSACIHESTVHSRVFQILYRNEEVPVNDAVIFRAHLLLDGERVEEALSEVDFQ

PF12394 // ENSGT00390000007885_1_Domain_0 (115, 177)

LKVDLH
FTDSQQQ-LRDVAGVPVISSRVLGLHFHPRRGLHHQVPVMFDYFHLSVISVTIHAALVAL
QQPLISFTRPGRGPWLGKGGPDTGPEQSSLSLENLVFGAGYCKPTSS-EGSFYVPSENCM
QHAYKWHRELCFLLLHAYRGLRAYFLTIMRDVPELPHMEL-ESLAVEETLSQLCSELQML
NNPEKIAE--QISKDLAWLAS-HLMALWTQFLDTVTLHSQVTTYLTQEHHTLRVRRFSEA
F--FYMEHQKLAVLTFQENLIQTHSQLSLDIRNSEYLTTMPPLPAECLDIDGDWSTLPVI
FEDRYVDCPAT-GH--HL-------SVYP--NFDAPAS--SPAITNLK------------
------------D-S----EE--NHIGSRDAAV--REDPV-LPT--RKP--PPKN-----
---------------SDEELVRCPEPEENVPT-------PSHVDMCS---E---------
S-QVYLTIGEFQDKPG-LP-------EAEH------------------------------
--------------WPGQRSDVGRHLLAD--------EDLPRSS---LGP----------
---------EDGQAPALTYIDVQSSSKNTCSA-----EPTVVTGAPHERGCWPSNSELHR
AELSQGGGG--------GSRQNATSSEKTTLR--ELS---P--LGKGADPGSK-------
----MVLLSLRLVP---SEPCDP-LNPSLRDPVGLRASPRDAPAEEQEEGPVLSGAIERS
SSVISDSGIESEPSSVAWSEARSRALELPGDREVLHQLVRRHALHRNSLEGGHTESNTSL
PSGIQASLTSISSLPFEEEERELA-RTKLTKSVSAPQISSPEESAEDADTTQPGGGLAET
PAEDSES------RDPSGPCLP-LSGGSG-----------------SRDA-GVAHLLAE-
-VVSDAS----HQQGPGYIDTPKGKE-KVDPQGPC-----------------CLDGRTDN
P--PGVET----KGLSL-KIPPILALENPKNQPLP---GAPVEAPKGRPEDA--NVGERP
LPNSG--ILDAETFTH--HKV--PE---V-SSTSAA-----NTVDLDSTSERG--SSPCT
AEDTVLR-R---------GARTFPEDGREEG----PACSP------VSRSLHSQSTGNQE
PRAGPSTVMSHLASAETFPLDSLKAVEVVNLSVSCTATCLPFSSVPKETPARAGFSSKQT
AFPITHQPLGSFGVVPTHSGKLEEEVSERMFS----FYQAKENFKKELKIDGFLYSDLSV
LASDIPYFPPEEEEENLE

PF05057 // ENSGT00390000007885_1_Domain_2 (1459, 1657)

DGIHLVVCVHGLDGNSADLRLVKTFIELGLPGGKLDFLMSEK
NQ-TDTFADFDTMTDRLLDEIIQHIQLYNLS-IARI--SFIGHSLGNII-IRSVLTRPRF
RYYLNKLHTFLSLSGPHLGTLYNNSTLVSTGLWLMQKLKKSGSLLQLTFRDNADLRKCFL
YQLSQKTGLQYFKNVVLVASPQDRYVPFHSARIEMCKTALKDRHTGPVYAEMINNLLRPL
VDAKDCTLIRHNVFHALPNTANTLIGRAAHIAVLDSELFLEKFF---LVA-GLNYFK---
---------

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-------------------------------S----FYQAKEKFKKELKIEGFLYSDSSV
LASDIPYFPPEEEEENLE

PF05057 // ENSGT00390000007885_1_Domain_2 (1459, 1657)

DGIHLVVCVHGLDGNSADLRLVKTFIELGLPGGKLDFLMSEK
NQ-MDTFADFDTMTDRLLDEIIQHIQLYNLS-ISRI--SFIGHSLGNII-IRSVLTRPRF
RYYLNKLHTFLSLSGPHLGTLYNNSTLVSTGLWLMQKLKKSGSLLQLTFRDNADLRKCFL
YQLSQKTGLQYFKNVVLVASPQDRYVPFHSARIEMCKTALRDRHTGPVYAEMINNLLGPL
VEAKDCTLIRHNVFHALPNTANTLIGRAAHIAVLDSELFLEKFF---LVA-GLNYFK---
---------

------------------------------------------------------------
-----------------------DIVFSIFFVYYIKVLMCWRKVEDALSEADFQLKLDLH
FTDSEQQ-LRDVPAIPMISSRTLCLHFHPRRGLHHHVPVMFDYFHLSVISVTVHASLVAL
HQPLISFARPGKGSWLGKGNLDAGPDQSSMSLENLVFGAGYCKPTSS-EGSFYVPSENCM
QHAYKWHKDLCLLLLNAQRGLHMYYTLIMKEIPDLPQLKL-EELSTEDTLSQLCTELQLL
SNPEKIAE--QISKDLAWLCS-HLLALWTQFLEVATLHPEVTAYLTQEHHMLRVRRFSEA
F--FYTEHQKLAVLTFQEGLIQSHGQISTEIRNSEYFTSMPPLPAECLDIDGDWNTLPVI
FEDRYMDLPCKVLA--LPWIKAQPTSISC--NFIVFIF--QVRCLVVRTGES-----KTI
FITATNFILRVTSSV----KK--SQNNNKKIKF--VGSLT-KST--QTG--FFIKKKYLV
LQAYKIILN-----IINNNLDVF--PDFEVPE-------HTQMDIID---N---------
----AVTKGDFGKGTL-LI-------HTDRINGNLSCLY-----SGTEGA-----AHAAK
GLNPHSTSQVCTLNKEGQRKPENI-FVSS--------KDTTDSE---PGNTECTSEEFKT
C--KEVLLKDNRLAADVTSGDMKPSNNDTHKSEP---EPVLIVSAQYECEACGTDSLEDR
SEIQKTAES--------GHPENNFTSE--LAL-SELT---S--LEKTADTDNK-------
----TLLPVLKALP---AHS------------LEVKLFTKEQRTEECEEFTLMSGVIKRS
SSIISDSGIESEPSSVAWSDARSRALELPSDREILHHLVRRHAIHRNSLEGGHTESNTSL
PSGIQASLTSISSLPFEEEIS------------------SPEEPVEEVDISKHSEATLGD
SEGYLKSCMETEDEETEDDDRIMDFSGCR-----------------ITTESGQLEPKGH-
-PI--PT----AKHSSGHMELHKEEAEESLSETYC--------SLECAKPPACPKSLRDN
I--SECQPLESNGECSL-KTPRANNYLDKSTEEFD----ACIKDPKDKPKPDSFEIEQGF
YTD--IRVTGEESFSQSINVL--PD-----ACDPVSAASETSTEFVSMQGECSRS----L
ADESQLVYT---------EMQGLQEIELNDSPA--SADPAS----GSYQDEYPQEPDSQD
HKLVANGTGFHSVTTEGVALESRKAVDVVNLSVSCTATCLPFSSVLKETPAMVGFSAKQA
VFPITRQPLGSFGVVSSNSNEVDEEANERMLN----FYQAKEKFKKEMKIEGFLYSDLSV
LASDIPYFPPEEEEEN

PF05057 // ENSGT00390000007885_1_Domain_2 (1457, 1658)

LEDGIHLVVCVHGLDGNSADLRLVKTFIELGLPGGKLDFLMSER
NQ-TDTFADFDTMTDRLLDEIIQHIQLYNLS-ISRI--SFIGHSLGNVI-IRSVLTRPRF
RYYLNKLHTFLSLSGPHLGTLYNNSTLVSTGLWLMQKLKKSGSLLQLTFRDNADLRKCFL
YQLSQKTGLQYFKNVVLVASPQDRYVPFHSARIEMCKNALKDRHTGPVYAEMINNLLQPL
IGAKDCTLIRHNVFHALPNTANTLIGRAAHIAVLDSELFLEKFF---LVA-GLNYFK---
---------

MCEVQGTVEFSVELQKFYNVDLFQRGYYQIRVTLKVSSRIPHRVSASIVGQTESS----S
PHSACVHESTVHSRVFQILYRNEEVSINDAVIFRAHLLLDGERVEDALSEVDFQ

PF12394 // ENSGT00390000007885_1_Domain_0 (115, 177)

LKVDLH
FTDSEQQ-LRDVAGAPMISSRTLGLHFHPRRGLHHQVPVMFDYFHLSVISVTIHAALVAL
QQPLISFTRPGRGSWLGKGGPDAGQEQSIISLENLVFGAGYCKPTSS-EGSFYVPSENCM
QRAHKWHRDLCLLLLQAYRGLRLYFLVIMKDIPELPDMDL-EALAVEETLSQLCSELQML
NNPEKIAE--QISKDLAWLAS-HLMALWTQFLDTVTLHSQVTTYLTQEHHTLRVRRFSEA
F--FYMEHQKLAVLTFQENLMQTHSQLSLDVRNSEYLASMPPLPAECLDIDGDCNTLPVI
FEDRYVDCPVT-GH--SL-------RVYS--NFHVPGT--IPTIMDLKEKEE--------
-----------------------NHIVNRTLSC--KESFV-LSMM--KP--TQMG-----
--------------SDEEEVSRCPEPGENVTT-------QNQVDMC---LE---------
S-EVYLTIGEFQNKAG-VP-------EDEC------------------------------
--------------RTGQGFDAGTYPSAE--------MDMPRRS---LGP----------
---------EDGQTPGLTYIDVKCNNKNPHRA-----EHMELLSVYQERRSCRDKYRFER
IVPSKMAAG--------GNHQDAICPDKTALP--ELH---S--LGKGADQEGK-------
----PGLLSLKLTP---AEPSDT-PSSTLTAPLEIRSSLQDPHTEEQEELSVLSGVIKRS
SSIISDSGIESEPSSVAWSEARSRALELPSDREVLQQLARRYTLHRNSLEGEPTESNTSL
PSGIQASLTSISSLPFEEEERELA-LTKLTKSVSAPQISSPEDTAEGADTTKKERGSAKA
SDIQSKSEVSPEHSSQ-------PCGSSRTED------------------DREGHSLAE-
-EDLGA----EKHQGPGYMDIPKGKETQSDLHGSC-----------------SLDGRTES
T--PGVET----KGHDL-KIPHTIALENAKTRSVH---RGQMETPKGRPKDL--NVGKHT
LSNSS--ISEVGELSHH--KV--PE---F-SCPSAANAIH-----PNSAGQQS--SSPCL
IHDMMLN-R---------TPDSSLEVEHDAG----TVCRT------VTHSIPSHVLRNQE
PKAGTSIMGSHLTPAETFTLDSLKAVEVVNLSLSCTATCLPFSSVPKETPARAGFSSKQT
PVPITHQPLGSFGVVSAHSSKLEDEVSERMFS----FYQAKEKFKKELKIEGFLYSDLSV
LASDTPYFPPEEEEENLE

PF05057 // ENSGT00390000007885_1_Domain_2 (1459, 1657)

DGIHLVVCVHGLDGNSADLRLVKTFIELGLPGGKLDFLMSEK
NQ-MDTFADFDTMTDRLLDEIIQHIQLYNLS-ISRI--SFIGHSLGNII-IRSVLTRPRF
RYYLNKLHTFLSLSGPHLGTLYNNSTLVSTGLWLMQKLKKSGSLLQLTFRDNADLRKCFL
YQLSQKTGLQYFKNVVLVASPQDRYVPFHSARIEMCKTALKDRHAGPVYAEMINNLLGPL
MAAKDCTLIRHNVFHALPNTANTLIGRAAHIAVLDSELFLEKFF---LVA-GLNYFK---
---------

MSEVQGTVEFSVELHKFYNVDLFQRGYYHIQLTLKVSSRIPHRLSASIVGQTESS----S
LHSACIHENTVHSRVFQILYRNEEVPINDAMIFRAHLLLDGERVEDALSEVDFQLKVDLH
FTDSEQQ-LRDVAGAPMISSRTLGLHFHPRRGLHHQVPVMFDYFHLSVISMTVHAALVAL
QQPLIXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXGSFYVPSESCI
QHAHKQHRALCLLLLHAHQGLRLYFLLILRDVPGLPRMEL-EGLAVEETLSQLCSELQML
NSPEKIAE--QISKDLAWLAS-HLMALWTQFLDTVTLQSQVTAHLTQEHHTLRVRRFSEA
F--FYMEHQKLAVLTFQENLIQSHSQLSLDVRHSEYLSSMPPLPAECLDIDGDCNTLPVI
FEDRYVDCPAT-GP--NV-------NVYP--TFDVPRT--NPAITSLKEKEE--------
-----------------------NHIVNRKSAF--REDLV-LAAV--KP--HQKD-----
---------------PARGGLQGPGPGDNTAA-------QHQEDVCS-------------
ESQVYLTIGEFQNKANVSA--------GEV------------------------------
--------------LTDQRSDVDICALAD--------VALPRKS---PGP----------
---------EDGQAPGLTYIDVKSSNKNCHRA-----DPIVVVSAECENQSPREHTGLDT
SVPSKVLAK--------GSRPNAISSDKATLH--DVN-----AYGKGADPEGR-------
----MLLLGLKLIP---SDPWET-SSSALREPLDVRSPPKDPQPEEREALSVLARIVKRS
SSIISDSGIESEPSSVAWSEARSRALELPSDRGVLHQLVRRHALHRNSLEDGPTESNTSL
PSGIQASLTSISSLPFEDEERELA-LTKLTKSVSAPQISSPEETADGTDARQPGASFAEA
LNSPEHGSQTRGSS------GT----G-----------------------SGEGYPLVK-
--VLDAD----SQQVLGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---XXXXXXXX
X--XXXXX-XXXXXXXX-XXXXXXXXXXXXXXXXX---XXXXXXXXXXXXXX--XXXXXX
XXXXX--XXXXXXXXXX-XXX--XX---X-XXXXXX------XXXXXXXXXXXXX--XXX
XXXXXXXXX---------XXXXXXXXXXXXX-X--XXXXX------XXX-----X--XXX
-XXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXX-XXX
XXXXXX--XXXXXXXXXXXX-XXXXXXXXXXX-----X--XXXXXXXXXXXXXXX-XXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX

PF05057 // ENSGT00390000007885_1_Domain_2 (1473, 1658)

XNSAVLLGKTFIELGLPGGKXXXXXXXX
XXXXXXXXXXXXXXX-XXXXX---XXXXXXXXXXXXXXXFIGHSLGNII-IRSVLTRPRF
RYYLNKLHTFLSLSGPHLGTLYNNSALVSTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXLQYFKNVVLVASPQDRYVPFHSARIEMCTTALKDRHTGPVYAEMINNLLGPL
VEAKDCTLIRHNVFHALPNTANTLIGRAAHIAVLDSELFLEKFF---LVA-GLNYFK---
---------

MSEIQGTVEFSVELHKFYNVDLFQRGYYQIRVTLKVSSRIPHRLSASIAGQTESS----S
LHSACVHDSTVHSRIFQILYRNEEVPINDAVVFRVHLLLGGERMEDALSEVDFQ

PF12394 // ENSGT00390000007885_1_Domain_0 (115, 177)

LKVDLH
FTDSEQQ-LRDVAGAPMVSSRTLGLHFHPRNGLHHQVPVMFDYFHLSVISVTVHAALVAL
QQPLISFTRPGRGSWLGKGGPDTGQEQSIISLENLVFGAGYCKPTSS-EGSFYITSENCM
QHAHKWHRDLCLLLLHAYRGLRLHFLVIMRDIPELPHTEL-EALAVEETLSQLCSELQML
NNPEKIAE--QISKDLAWLTS-HMMALWTQFLDTVTLHSQVTTYLTQEHHTLRVRRFSEA
F--FYMEHQKLAVLTFQENLIQTHSQLSLDIRNSEYLTSMPPLPAECLDIDGDWNTLPVI
FEDRYVDCPAT-GH--NL-------SVYP--NFDVPVT--SPTIMNLK------------
------------D-K----ED--NCMVNSNISF--REDLV-LST--IKP--PQMD-----
---------------SDEEVIRCPDPAENVAT-------QNHMDMCS---E---------
S-QVYISIGEFQNKAG-VP-------EDEC------------------------------
--------------WTGQTSDAGTYPVAD--------VDTSRRS---PGP----------
---------EDGQAPVLTYIDVKSSNKNPSRA-----EPLVAFNAQHESRSSRDKYGLDR
TGLSKVVVG--------GSHQNAISSDKTTLH--ELS---T--LGKGIDQEGK-------
----MVLLSLKLTP---SEPCDP-LSSTLREPLDIRSSLKDSHTEEQEELSVLSGVIKRS
SSIISDSGIESEPSSVAWSEARSRALELPSDREVLHPFVRRHALHRNSLEGGHTESNTSL
PSGIQASLTSISSLPFEEDEREVA-LTKLTKSVSAPHISSPEEAAEDADTKQQDGGFAEH
SDMHSKS------QGSPGSCSQ-LCGDSG------------------TDA-GADHPLVE-
-IVLDAD----NQQGPGYIDIPKGKGKQFDAQGHC-----------------LPDGRTEN
T--PGVET----KGLNL-KIPRVIALENPRTRSLH---RALEETPKGMPKDL--NVGQQA
LSNSG--ISEVVGLSQ--HQV--PE---L-SCTSAA-----DAINMNSTGQQSQSGSPCI
TDDTAFN-R---------GVNAFPEAKHKAG----TVCPT------VTHSVHSQVLKNQE
LKAGTSIMGSHLTSAETFTLDSLKAVEVVNLSVSCTATCLPFSSVPKETPARAGFSSKQT
LFPITHQPLGSFGVVSTHSSTLDEEVSERMFS----FYQAKEKFKKELKIEGFLYSDLTV
LASDIPYFPPEEEEENLE

PF05057 // ENSGT00390000007885_1_Domain_2 (1459, 1657)

DGIHLVVCVHGLDGNSADLRLVKTFIELGLPGGKLDFLMSEK
NQ-MDTFADFDTMTDRLLDEIIQHIQLYNLS-ISRI--SFIGHSLGNII-IRSVLTRPRF
RYYLNKLHTFLSLSGPHLGTLYNNSTLVSTGLWLMQKLKKSGSLLQLTFRDNADLRKCFL
YQLSQKTGLQYFKNVVLVASPQDRYVPFHSARIEMCKTALKDRHTGPVYAEMINNLLGPL
VEAKDCTLIRHNVFHALPNTANTLIGRAAHIAVLDSELFLEKFF---LVA-GLNYFK---
---------

MSEVQGTVEFSVELHTFYNVDLFQRGXXXXXXXXXXXXXXXXXXXXXXXXXXXSG----S
LHSACVHESTVHSRVFQILYRNEEVPINDAVIFRAHLLLDGERVEEALSEVDFQLKVDLH
FTDSEQQ-LRDMAGVPVISSRALGLHFHPRRGLHHQVPVMFDYFHLSVISVTIHAALVAL
QQPLISFTRPGRGSWLGKGGPDTGPEQSSLSLENLVFGAGYCKPTSS-EGSFYVPSDNCM
QHAYKWHRDVCFLLLHAYRGLRAYFLTIMRDIPELPRMEL-ESLAVEETLSQLCSELQML
NNPEKIAE--QISKDLAQLAS-HLMALWTQFLDTVTLHSQVTAYLTQEHHTLRVRRFSEA
F--FYMEHQKLAVLTFQENLIQTHSQLSLDVRNSEYLATMPPLPAECLDIDGDWNTLPVI
FEDRYVDCPATXXX----------XXXXP--GFDVAAT--SPAILNLNDR----------
-------------------EE--NHIVNRKSSL--REDLV-LPT--MKP--PQMD-----
---------------SNEEVIRCPGPNENVTT-------PSHMDVCS---E---------
S-QVYLTIGEFQNKPG-LP-------EDER------------------------------
--------------RTGQRSDVGTQPPTD--------EDLPRRS---PGP----------
---------EDDQAPALTYMDVNSSNKNPCRA-----DPIAVTSTQHESGCSRDNYELDR
TELSKGVAG--------GGHHDASSSEKTTLH--ELS---T--LGKGADQGSK-------
-----MVLSLKLIP---SEPCDP-LSSSLRDPLDVKASPEDPHSEEREGVSVLSGVIKRS
SSIISDSGIESEPSSVAWSEARSRAQELPSDRDVLHQLVRRHALHRNSLEGGHTESNTSL
PSGIQASLTSISSLPFEEEERELA-LTKLTKSVSAPQISSPEESAEGGDSLQQGRGLPET
SAVHARS------TDPSGHRLQ-------------------------LSNAGVHHSLVE-
-VVSDAD----GQQGPGYIDIPKGKEDPLDPQGPC-----------------CLDGRTDN
P--PGLET----KGLSL-KIPRIPALETPRYRAFP---RELMETPERMPKDS--NVGKRA
LSNSS--ILDVEHFTR--REV--PE---V-SCTSAA-----EIINLDSAGERS--SSPGV
IDDTALS-R---------GPDTFPEDGREAG----AVCST------GTHSIHSQATGNQE
PRAGPSVMLSHVTSAETFSLDSLKAVEVVNLSMSCTATCLPFSSVPKETPARAGFSSKQT
PFPITHQPLGSFGGVPNHSSKLEEEVSERMFS----FYQAKEKFKKELKIDGFLYSDSSV
LASDIPYFPPEEEEEN

PF05057 // ENSGT00390000007885_1_Domain_2 (1457, 1658)

LEDGIHLVVCVHGLDGNSADLRLVKTFIELGLPAGKLDFLMS-K
NH-MDTFADFDTMTDRLLDEIIQHIQLYNLS-ISRI--SFIGHSLGNII-IRSVLTRPRF
RYYLNKLHTFLSLSGPHLGTLYNNSTLVSTGLWLMQKLKKSGSLLQLTFRDNADLRKCFL
YQLSQKTGLQYFKNVVLVASPQDRYVPFHSARIEMCKTALKDRHTGPVFAEMINNLLRPL
VDAKDCTLIRHNVFHALPSTANTLIGRAAHIAVLDSELFLEKFF---LVA-GLNYFK---
---------

MSEIQGTVEFSVELHKFYNVDLFQRGYYQIRVTLKVSSRIPHRLSASIAGQTESS----S
LHSACVHDSTVHSRIFQILYRNEEVPINDAVVFRVHLLLGGERMEDALSEVDFQ

PF12394 // ENSGT00390000007885_1_Domain_0 (115, 177)

LKVDLH
FTDSEQQ-LRDVAGAPMVSSRTLGLHFHPRNGLHHQVPVMFDYFHLSVISVTVHAALVAL
QQPLISFTRPGRGSWLGKGGPDTGQEQSIISLENLVFGAGYCKPTSS-EGSFYITSENCM
QHAHKWHRDLCLLLLHAYRGLRLHFLVIMRDIPELPHTEL-EALAVEETLSQLCSELQML
NNPEKIAE--QISKDLAWLTS-HMMALWTQFLDTVTLHSQVTTYLTQEHHTLRVRRFSEA
F--FYMEHQKLAVLTFQENLIQTHSQLSLDIRNSEYLTSMPPLPAECLDIDGDWNTLPVI
FEDRYVDCPAT-GH--NL-------SVYP--NFDVPVT--SPTIMNLK------------
------------D-K----ED--NCMVNSNLSF--REDLV-LST--IKP--SQVD-----
---------------SDEEVIRCPEPAENVAT-------QNHMDMCS---E---------
S-QVYISIGEFQNKAG-VP-------EDEC------------------------------
--------------WTGQTSDAGTYPVAD--------VDTSRRS---PGP----------
---------EDGQAPVLTYIDVKSSNKNPSRA-----EPLVAFNAQHESRSSRDKYGLDR
TGLSKVVVG--------GSHQNAISSDKTTLH--ELS---T--LGKGIDQEGK-------
----MVLLSLKLTP---SEPCDP-LSSTLREPLDIRSSLKDSHTEEQEELSVLSGVIKRS
SSVISDSGIESEPSSVAWSEARSRALELPSDREVLHPFVRRHALHRNSLEGGHTESNTSL
PSGIQASLTSISSLPFEEDEREVA-LTKLTKSVSAPHISSPEEAAEDADTKQQDGGFAEP
SDMHSKS------QGSPGSCSQ-LCGDSG-----------------T-DA-GADHPPVE-
-IVLDAD----NQQGPGYIDIPKGKGKQFDAQGHS-----------------LPDGRTEN
T--PGVET----KGLNL-KIPRVVALENPRTRSLH---RALEETPKGMPKDL--NVGQQA
LSNSG--ISEVEGLSQ--HQV--PE---L-SCTSAA-----DAISMNSTGQQSQSGSPCI
TDDTAFN-R---------GVNAFPEAKHKAG----TVCPT------VTHSVHSQVLKNQE
LKAGTSIMGSHLTSAETFTLDSLKAVEVVNLSVSCTATCLPFSSVPKETPARAGFSSKQT
LFPITHQPLGSFGVVSTHSSTLDEEVSERMFS----FYQAKEKFKKELKIEGFLYSDLTV
LASDIPYFPPEEEEENLE

PF05057 // ENSGT00390000007885_1_Domain_2 (1459, 1657)

DGIHLVVCVHGLDGNSADLRLVKTFIELGLPGGKLDFLMSEK
NQ-MDTFADFDTMTDRLLDEIIQHIQLYNLS-ISRI--SFIGHSLGNII-IRSVLTRPRF
RYYLNKLHTFLSLSGPHLGTLYNNSTLVSTGLWLMQKLKKSGSLLQLTFRDNADLRKCFL
YQLSQKTGLQYFKNVVLVASPQDRYVPFHSARIEMCKTALKDRHTGPVYAEMINNLLGPL
VEAKDCTLIRHNVFHALPNTANTLIGRAAHIAVLDSELFLEKFF---LENKGLGKVTALI
KTNRRRGQK

MSEVQGTVEFSVELHKFYNVDLFQRGYYQIRMTLKVSSRIPHRLSASIVGQAESS----T
LHSACVHESTVHSRVFQILYRNEEVPINDAMIFRAHLLLDGERVEDALSGVEFQ

PF12394 // ENSGT00390000007885_1_Domain_0 (115, 177)

LKVDLH
FTDSEEQ-LRDVAGAPMISSRTLGLHFHPRRGLHHQVPVMFDYFHLSVISVTIHAALVAL
QQPLISFARPGRGSWLGKGGPDMGTEQSIISLENLVFGAGYCKPTSS-EGSFYVPSENCM
QHAHKWHRDLCLLLLQAYRGLRLYFLLIMRDIPELPHMEL-EALAVEETLAQLCSELQML
NNPEKIAE--QISKDLAWLAS-HLMALWTQFLDTVTLHSQVTTYLTQEHHSLRVRRFSEA
F--FYMEHQKLAVLTFQENLIQMHSQLSLDIRNSEYLTSMPPLPAECLDIDGDWNTLPVI
FEDRYVDCPAT-GP--DL-------NVYP--NFKVPTV--SPSMMNLK------------
------------E-K----EE--NHVINRKSSF--RGDFV-LST--RIP--PQVD-----
---------------TNEEVTRCPEPDKNETT--------ANVDVCS---E---------
S-QVYLTIGEFQNKAG-VP-------EDEC------------------------------
--------------GSGQMSDVRTHPLAD--------VDSLRRS---PGP----------
---------EEGQSTVLTYIEVKSSNQGLHKA-----EPTELSS---ESRSPRDS---YR
TVSSEVVAG--------GYHQNAISSDKAPIT--ELS---T--SGKGTEPEGQ-------
----PVLLSLRLAP---T---ETPLSATLTEPLDPRSSFQDPPVEEQEELSTMSGAIKRS
SSLISDSGIESEPSSVAWSEARSRAVELASDREVLHQLVRRHALHRNSLEGGHTESNTSL
PSGIQASLTSISSLPFEEEERELA-LTKLTKSASAPQISSPEDATEGAGTMKKRGDFPEA
SEMR-KS------GGSPEHSSQ-PSGRPR-----------------AQDA-RAAQPFGE-
-TVSRAD----KHQDPGYMDIPQGKESQVEPQGHS-----------------RLDGRTEN
T--PESET----KGLNV-KIPRSIALENPRARSLH---RALMETPKGRPKDS--HVGKHI
LSSSS--VSDVGEMSH--HKV--PE---F-SCTSAS-----DATTPNP----EHSGAPGA
VGHVVSP-R---------EPDAFLEDEPEAG----TVCHA------LTPPIPSQILRNQE
LRTGASIMGPPLASAETFSLESLKTVEVVNLSLSCTATCLPFSSVPKETPARAGFSSRQT
PVPITHQPLGSFGVVATHSSKLEEDVGERMFS----FYQAKEKFKKELKIEGFLYSDLSV
LASDIPYFPPEEEEENLE

PF05057 // ENSGT00390000007885_1_Domain_2 (1459, 1657)

DGIHLVVCVHGLDGNSADLRLVKTFIELGLPGGKLDFLMSEK
NQ-TDTFADFDTMTDRLLDEIIQHIQLYNLS-ISRI--SFIGHSLGNII-IRSVLTRPRF
RYYLNKLHTFLSLSGPHLGTLYNNSTLVSTGLWLMQKLKKSGSLLQLTFRDNADLRKCFL
YQLSQKTGLQYFKNVVLVASPQDRYVPFHSARIEMCKTALKDRHTGPVYAEMINNLLGPL
IEAKDCTLIRHNVFHALPNTANTLIGRAAHIAVLDSELFLEKFF---LVA-GLNYFK---
---------

MSEVQGTVEFSVELHKFHNVDLFQRGYYQIRAGLKLPTRIPHRLTATVVEQTGDS----S
LSSACVHENNVLSRIFQILYRNEEIVMNESMSFRVHLLLDGERVEDALSEADFQ

PF12394 // ENSGT00390000007885_1_Domain_0 (115, 178)

LKLDLH
FTDSEQQ-LRDIPAIPVISSRTLGLHFHPRRGLHHHVPVMFDYFHLSVISVTVHASLVAL
HQPLISFARPGKGSWLGKGSLETGPDQTSMSLENLVFGAGYCKPTAS-ERAGCRPREVCR
QH----------------------------------------------------------
------------------------------------------------------------
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---------

---------------------------------------------------AESS----S
LHSACVHENTVHSRVFQILYRNEEVPINDAMIFRAHLLLDGERVVSIKDRVAFHLEKSLR
LSDSSDK

PF12394 // ENSGT00390000007885_1_Domain_0 (128, 178)

-LRDVAGAPMISSRTLGLHFHPRRGLHHQVPVMFDYFHLSVISVTIHAALVAL
QQPLISFTRPGRGSWLGKGGPDTGPEPSIISLENLVFGAGYCKPASS-EGSFYVPSENCM
QHAHKWHRDLCLLLLHAYRGLRLYFLAIMRDIPELPHMEL-EALAVEETLSQLCSELQML
NNPEKIAE--QISKDLAWLAS-HLMALWTQFLDTVTLHSQVTTYLTQEHHTLRILRSKEA
FSGFYLGYAAICYTKLKNGEIQTHSQLSLDVRNSEYLSSMPPLPAECLDIDGDWNTLPVI
FEDRYVDCPAT-GP--NV-------SVYP--NFDVPVT--SPAITSLK------------
------------E-K----EE--SRIVNSNSSF--RDDLV-LAT--MKP--IQMN-----
---------------SNEEGTRCPEPGDSVTT-------QNKMDTCC---E---------
S-QVYLTIGEFQNKSN-VS-------EDEF------------------------------
--------------LTGQRADVCAYALAD--------VDTPRKS---SGP----------
---------EDGQAPALTYIDVKSSNKNPHRA-----EPIVVISAECENQSAGDNIRLDR
AVPSKVVAS--------GSHQNAISSDKVTLH--ET----S--VGKGADQEGR-------
----MVLLGLKLLP---SEPWESLG-SAL-------------REQEQEALSVLSGVIKRS
SSIISDSGIESEPSSVAWSEARSRALESPSDREVLHQLVRRHALHRNSLEGGHTESNTSL
PSGIQASLTSISSLPFEEEERELA-LTKLTKSVSAPQISSPEETAEDGDSKQQGAAFAEA
LAMHSKN------KDSLEHGSQ-PCGGSR-----------------IQGS-GGECSLVE-
-IILDTD----NQQGPGYMDIPKGKGSQFDPQGHC-----------------HLDGRTEN
T--AGIET----KGFTS-KIPRITALENSRTRSFH---KTLMETPKGMPSDL--TVGKGT
LSNSC--ISEAGGISH--PKV--PA---L-SCLSAA-----DAIDLNSAGEC--GSSPCV
VDDKAVK-R---------GATAFLEAEREAG----TVCPT------VTHPVPTQVLRSQE
PKAGSSVA--QLAYAESFTLESLKAVEVVNLSVSCTATCLPFSSVPKETPARVGFSSKQT
PFPITHQPLGSFGVVSTHSSKLEEEVSERMFS----FYQAKEKFKKELKIEEFLYSDLSV
LASDRPYFPPEEEEENLE

PF05057 // ENSGT00390000007885_1_Domain_2 (1459, 1657)

DGIHLVVCVHGLDGNSADLRLVKTFIELGLPGGKLDFLMSEK
NQ-MDTFADFDTMTDRLLDEIIQHIQLYNLS-ISRI--SFIGHSLGNII-IRSVLTRPRF
RYYLNKLHTFLSLSGPHLGTLYNNSALVSTGLWLMQKLKKSGSLLQLTFRDNADLRKCFL
YQLSQKTGLQYFKNVVLVASPQDRYVPFHSARIEMCKTALKDRHTGPVYAEMINNLLGPL
VEAKDCTLIRHNVFHALPNTANTLIGRAAHIAVLDSELFLEKFF---LVA-GLNYFK---
---------

MSEVQGTIEFSVELHKFHNVDLFQRGYYHVRASLKTSARTPHRLVATLVGQTGAKANDPG
PYPPCVYDNVVFSRVFQILYRNEDIEINDVMAFKVHLLLDGERVEDALSEVDFQLKLDLH
FTDSEQLLLRDIPAVALISSRTLGLHFHPTSGLHHHVPVMFDYFHLSVISVTVHGSLVAL
HQPLLSFARPVKGSWLGKSGLEPVTDNSNVSMEDLVFGAAYCKPPSS-EGSCYALSEDCI
QHAYKWHKDLCQLLLTAYNALGSYYANILKEIPDLPHTETAEELSTERTLCQLCNQLQNG
ANMDSLND--FLNLILPLLSL-LLMAFATQFGGFISGFQNIKNQLANPTVMPRVRRFSEA
F--FCTEHEKPAVLTFQENLIQSHSNLSTEIRNSEYLAAMPPLPMECLDIDGDWTSLPII
FEDRYVECPKK-GTIRYQFFYVTKDIKFTTQEGGVAEA--HQSTVGTEAAGEANPIGYTS
FTP------KVITQC----Q------PNNKIGLKSNIKVYQQSTVGTEAAGEANPIGYMS
F--------------TPKVITQCQHYIMDNA-----LLEPTNENVCESNKEFPPENTHIN
SKPHFIQSTTVHDNASFEKLGVCTEAQEDCYTESP-------------------------
-------EQCFDYNQ--EAASVESESLAD-----LNQLYIPPSEISDCGAELSLSTANED
CDQATRCHQEPKKTPGVTYIEVKPQSQDKYKG-----EPVLIVNSQYGNTTSLANDEATQ
SEGHPMTQE---------HTNDTRTYEHIALH--EVR-----------ST--K-------
----NELISISKSQ--KSRQCSHTLL-------------KSSS--TELIRNSTEGGIKRS
SSVISDSGIESEPSSVAWCDLHNRTMDLTSDKDLLLQLSK------QNWEGERTESNTSL
PSGIQASLASINSLPFEEEDREME-LSKLTKSVSAPQISSPEETLNDLILNNKVVGEIIH
---SLTQCSSDDKEEE-RQTAM--------------------------------------
---------------NYYNNITNGIISELVNETCNQLVQPGTKSHESSLANALIQGLI--
---PDSEA----GV--------IDAYIVPKADDFPSVHPKAIMCDLSSPHDQYLMAKATS
YSVSP--LVDANSITHTSFSVIAPANEIFQDCPVLHQT---ELV------EDS----VES
TDQSIDNYY-----------HELYSIEQEVT-NTRTDCAS--------------------
-----ELEESNASMSTVRVLERRNGVELVNLSVSCTATCLPFSSMQKDTPAIPGFSTKQA
LFPITRQPLGSFEVVSSNSN-TDEDSNERMLS----FHQAKHKFRKELKFEGFIYSDQPV
LASDVPYFPAEE--EQ

PF05057 // ENSGT00390000007885_1_Domain_2 (1457, 1658)

TEDGIHLVVCVHGLDGNSADLRLVKTFLELGLPGANLDFLMSEK
NQ-TDTFADFDAMTDRLIDEIVQHIQLYNLS-ISRI--SPKTHSLYKSLSVPLVKCHFKY
KYSLPKLFSYKSRTGRLLSVYKGHSFLSFPGLWLMQKLKKSGSLLQLTFRDNTDLRKCFL
YQLSQKPGLQYFKNVVLVASPQDRYVPFHSARIEMCKNATKDKHTGPVYTEMLNNLLQPV
IDSKDCTLIRHNVFHALPNTANTLIGRAAHIAVLDSELFLEKFF---LVA-GLGYFK---
---------

MSEIQGTVEFSVELHKFYNVDLFQRGYYQIRVTLKVSSRIPHRLSASIAGQTESS----S
LHSACVHDSTVHSRIFQILYRNEEVPINDAVVFRVHLLLGGERMEDALSEVDFQ

PF12394 // ENSGT00390000007885_1_Domain_0 (115, 177)

LKVDLH
FTDSEQQ-LRDVAGAPMVSSRTLGLHFHPRNGLHHQVPVMFDYFHLSVISVTVHAALVAL
QQPLISFTRPGRGSWLGKGGPDTGQEQSIISLENLVFGAGYCKPTSS-EGSFYITSENCM
QHAHKWHRDLCLLLLHAYRGLRLHFLVIMRDIPELPHTEL-EALAVEETLSQLCSELQML
NNPEKIAE--QISKDLAWLTS-HMMALWTQFLDTVTLHSQVTTYLTQEHHTLRVRRFSEA
F--FYMEHQKLAVLTFQENLIQTHSQLSLDIRNSEYLTSMPPLPAECLDIDGDWNTLPVI
FEDRYVDCPAT-GH--NL-------SVYP--NFDVPVT--SPTIMNLK------------
------------D-K----ED--NCMVNSNLSF--REDLV-LST--IKP--SQVD-----
---------------SDEEVIRCPEPAENVAT-------QNHMDMCS---E---------
S-QVYISIGEFQNKAG-VP-------EDEC------------------------------
--------------WTGQTSDAGTYPVAD--------VDTSRRS---PGP----------
---------EDGQAPVLTYIDVKSSNKNPSRA-----EPLVAFNAQHESRSARDKYGLDR
TGLSKVVVG--------GSHQNAISSDKTTLH--ELS---T--LGKGIDQEGK-------
----MVLLSLKLTP---SEPCDP-LSSTLREPLDIRSSLKDSHTEEQEELSVLSGVIKRS
SSVISDSGIESEPSSVAWSEARSRALELPSDREVLHPFVRRHALHRNSLEGGHTESNTSL
PSGIQASLTSISSLPFEEDEREVA-LTKLTKSVSAPHISSPEEAAEDADTKQQDGGFAEP
SDMHSKS------QGSPGSCSQ-LCGDSG-----------------T-DA-GADHPPVE-
-IVLDAD----NQQGPGYIDIPKGKGKQFDAQGHC-----------------LPDGRTEN
T--PGVET----KGLNL-KIPRVIALENPRTRSLH---RALEETPKGMPKDL--NVGQQA
LSNSG--ISEVEGLSQ--HQV--PE---L-SCTSAA-----DAISMNSTGQQSQSGSPCI
TDDTAFN-R---------GVNAFPEAKHKAG----TVCPT------VTHSVHSQVLKNQE
LKAGTSIMGSHLTSAETFTLDSLKAVEVVNLSVSCTATCLPFSSVPKETPARAGFSSKQT
LFPITHQPLGSFGVVSTHSSTLDEEVSERMFS----FYQAKEKFKKELKIEGFLYSDLTV
LASDIPYFPPEEEEENLE

PF05057 // ENSGT00390000007885_1_Domain_2 (1459, 1657)

DGIHLVVCVHGLDGNSADLRLVKTFIELGLPGGKLDFLMSEK
NQ-MDTFADFDTMTDRLLDEIIQHIQLYNLS-ISRI--SFIGHSLGNII-IRSVLTRPRF
RYYLNKLHTFLSLSGPHLGTLYNNSTLVSTGLWLMQKLKKSGSLLQLTFRDNADLRKCFL
YQLSQKTGLQYFKNVVLVASPQDRYVPFHSARIEMCKTALKDRHTGPVYAEMINNLLGPL
VEAKDCTLIRHNVFHALPNTANTLIGRAAHIAVLDSELFLEKFF---LENKGLGKVTALI
KTNRRRGQK

--------------------------YYQIRMTLKVSSRIPHRLSASIVGQTDSS----S
LQSACAHENAVHSRVFQILYRNEEVPINDAVIFRAHLLLDGERVEEALSEVDFQLKVDLH
FTDSEQQ-LRDVAGAPLISSRTLGLHFHPRRGLHHQVPVMFDYFHLSVISVTIHAALVAL
QQPLISFTRPGRGSWLGKGGPDTGPEQSSLSLENLVFGAGYCKPTSS-EGSFYVPSETCM
QHAHRWHRELCFLLLHAYRGLRAYFLGIMTDIPELPHMEL-ESLAVEETLSQLCSELQML
NNPEKIAE--QISKDLAWLTS-HLMALWTQFLDTVTLHSQVTSYLTQEHHTLRVRRFSEA
F--FYMEHQKLAVLTFQENLIQTHSQLSLDIRNSEYLTTMPPLPAECLDIDGDWNTLPVI
FEDRYVDCPAT-GH--NL-------SVYP--NFDVPMT--NPAIMNLKDREE--------
-----------------------NPIVNRKSPF--REDLA-LPTM--KP--PQVD-----
--------------SDE-DVIRCPEPDDNVNT-------PKRADMC---SE---------
S-QVYLTIGESQNKAG-LP-------EEEC------------------------------
--------------WTGQRSDVGTHPSAD--------EDLPRRS---PGP----------
---------EDGQALALTYIDVKSSNKRPCSA-----EPTVVISAQQESEHSPDNYDSDR
AVPGQEVAG--------GGHQNTILSEKTMLH--ELS---T--LGKVADQEGK-------
----VVLLSLKLIP---SEPCDP-LNLTLRDPLDVRASPKDPHTEEQEEVLVLSGVIKRS
SSIISDSGIESEPSSVAWSEARSRALELPSDREVLHHLVRRHALHRNSLEGGHTESNTSL
PSGIQASLTSISSLPFEEEERELA-LTKLTKSVSAPQISSPEESAEDTDTMQQGGDLAES
PAVPVE--------SL-------DSPGSRIQD------------------AGEDHSLTQ-
-VVSGA----DSQQGPGYIDIPKGTESQFDPQGPC-----------------CLDGRTEN
P--LGVET----KGLNL-KIPRIIALENPRHGSCP---RVLMETPEGMPEDL--NVGKDA
LSDSS--ISDDETIAHH--KV--PE---W-SCREAADASK-----LGSVGEQR--SSPCI
IDDATFS-K---------GAHAPLEAGREAG----IVCST------VTHSIHSQVLGNQE
PRTGTSFMASHLSPAENFTLDSLKAVEVVNLSVSCTATCLPFSSVPKETPARAGFSAKQT
PLPITHQPLGSFGVVSTHSSKLEEEVSERMYS----FYQAKEKFKKELKIDGFLYSDLSV
LASDIPYFPPEEEEEN

PF07819 // ENSGT00390000007885_1_Domain_2 (1457, 1700)

LEDGIHLVVCVHGLDGNSADLRLVKTFIELGLPGGKLDFLMSEK
NQ-MDTFADFDTMTDRLLDEIIQHIQLYNLS-ISRI--SFIGHSLGNII-IRSVLTRPRF
RYYLSKLHTFLSLSGPHLGTLYNNSTLVSTGLWLMQKLKKSGSLLQLTFRDNADLRKCFL
YQLSQKTGLQYFKNVVLVASPQDRYVPFHSARIEMCKTALKDRHTGPVYAEMIDNLLRPL
VDAKDCTLIRHNVFHALPNTANALIGRAAHIAVLDSELFLEKFF---LVA-GLSYFK---
---------

MSEVQGTVEFSVELHKFHNVDLFHRGYYQVRVALKVSSRIPHRLSASIVGQTESG----S
LHAACVHESNVHSRVFQILYRNEEVPIGDAAVFRAHLLLDGERVEEALSEVDFELKVDLH
FTDSEQQ-LRDAAGAPVISSRTLGLHFHPRRGLHHQVPVMFDYFHLSVISVTVHAALVAL
QQPLISFTRPGRGSWLGKGSPEAGPEQSSLSLENLVFGAGYCKPTSSEQGSFYVPSENCM
QRAHKWHRGLCLLLLHAYRGLRAYFLLIMRDVPELPHMEL-ESLAVEETLNRLCLELQML
NNPEKIAE--QISKDLAWLAS-HLMALWTQFLDTVTLHAHVTAYLTQEHHTLRVRRFSEA
F--FYMEHHKLAVLTFQENLVQSHSQLSLDLRNSEYLSTMPPLPAECLDIDGDGSTLPVI
FEDRYVDCPAPVGQ--SL-------SVYP--NFTVPAT--SPAQMSLK------------
------------D-R----EE--DPLVNRKPSF--RENLI-LPT--PKP--PQMD-----
---------------CDEEVLLGPASEEEVGT-------PSPADVLS---E---------
S-QVYLTIGESPDTAA-VP-------AGEG------------------------------
--------------RTGQRADVGMDSLAD--------DDPPGGS---PGP----------
---------EDGWGPTLAYLEVKSSNKHPGRA-----EPTVATSDQHGGGHFRENRELDS
TLPSTALAG--------GSRQPAVSWEKTPLL--ESR---A--PGKGADQEAK-------
----TLLLSLKPFP---REPCGP-LSSALRDPPEARAAPRDPPPEEQEEGSVLSGVIKRS
SSLISDSGIESEPSSVAWSEARGRALEVPSDREVSHPLLRRHTPHRNSLEGGHTESSLSL
PSGIQASLTSISSLPFEEEERELALLTKLTKSASAPQISSPEEAAEDAGAVRPGAGPAET
PGQLASS------IEAPGQGRPPSDGGSS-----------------IQDT-GVGPSLVE-
-VAL-DA----DQQGAGYLDIPQDKGAHADPPGPR-----------------RLDGRTEN
P--PGAGT----KGVHL-AIPRGTARASPRDRAFP---GVQTEAPKRMPADA--GVGSSP
GSHGG--RSDMASLPD--HAV--PA---L-SRPPAV-----DAAALGSTGQRR--GSPRI
IEEAAFG-R---------GAHTM-DRGHQAG----AACPA------VTHSIHSQILGPQE
PRAGTSAMGPPLAPAEAFSPDSLKAVEVVNLSVSCTATCLPFSSVPKETPARAGFSSRQT
PLPITHQPLGSFGAVSTHPSALEEGVGERMFS----FYQAKEKFKKELKIDGFLYSDLSV
LASDMPYFPPEEEEEN

PF05057 // ENSGT00390000007885_1_Domain_2 (1457, 1658)

LEDGIHLVVCVHGLDGNSADLRLVKTFIELGLPGGKLDFLMSEK
NQ-MDTFADFDTMTDRLLDEIIQHIQLYSLS-IARI--SFIGHSLGNII-IRSVLTRPRF
RYYLSKLHTFLSLSGPHLGTLYNNSTLVSTGLWLMQKLKKSGSLLQLTFRDNADLRKCFL
YQLSQKTGLQYFKNVVLVASPQDRYVPFHSARIEMCKTALKDRHTGPVYAEMINNLLRPL
VEAKDCTLIRHNVFHALPNTANTLIGRAAHIAVLDSELFLEKFF---LVV-GLNYFK---
---------

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---------------------------IIFSS----FYQAKEKFKKDLKIEGYLYSDLSV
LASDTPYFPPEEEEENLE

PF05057 // ENSGT00390000007885_1_Domain_2 (1459, 1657)

DGIHLVVCVHGLDGNSADLRLVKTFIELGLPGGKLDFLMSEK
NQ-MDTFADFDTMTDRLLDEIIQHIQLYNLS-ISRI--SFIGHSLGNII-IRSVLTRPRF
RYYLNKLHTFLSLSGPHLGTLYNNSTLVSTGLWLMQKLKKSGSLLQLTFRDNADLRKCFL
YQLSQKTGLQYFKNVVLVASPQDRYVPFHSARIEMCKTALKDRHTGPVYAEMINNLLGPL
VAAKDCTLIRHNVFHALPNTANTLIGRAAHIAVLDSELFLEKFF---LVA-GLNYFK---
---------

-----------------------------------------------------VS----N
LGSASVQDNTVNSRIFQILYRNEEIVINELMTFRVHLLLDGER-ENALSEVDFQLKLDLH
FTESEQQ-ARDLAGMPAISSRTLGLHFQPRRGLHHHIPVMFDYFHLSVISVTIHASLVAL
QQPLIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XGSFYTPSENCM
QHAYKWHRDLCHLLLNTYQELYVYFLILMKDIPDFPRMKL-XXXXXXXXXXXXXXXXXXX
XXXXXXXX--XXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVRRFSEA
F--FYVEHQKLSVLTFQESVIQRQSQIALDVRNSEYFTSMPL--PACLDIDGXXXXXXXX
XXXXXXXXXXX-XY--NL-------GISP--NVAAPVK--TTPKVEQKEKEK--------
-----------------------SQQSNTNATS--EKIAFREDVF---------T-----
--------------AQAEVDYLCPGIRGEVST-------ER--YSPP-SST---------
S-QVYLTIGESXXXXX-XXXXXXXXXXXXX------------------------------
--------------XXXXXXXXXXXXXXX--------XXXXX-----XX-----------
----------XXXXXXXXXXXXX---XXXXXX-----XXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXX--------XXXXNVASTDKVVLN--ELN---K------RRQENK-------
----TTLLSLKSSE-----LDDS-SSPTPRDPLDVHSLPRDPKSNEREVLSALSGTIKRS
SSVISDSGIESEPSSVAWSEARSRALELPSDREVLHQLVRRHAIHRNSLEGGHTESNTSL
PSGIQASLTSISSLPFEEEEREVA-LNKLTKSVSAPQISSPEELAEDNDTREYRDL--EL
SEIQGRN--------IDSLGTFGFQNDPPKH------------------DCEVFHSLVE-
-MVFDTD---HPQEDKGYMDLAEVNDNPHFLFGHC-----------------SYVGGAEY
S--SMTKT----KEPTL-DILHVSE-VDTPRMMFN---EGLLENPKAESEVS--KTENDI
FSHIN--ISAIEDFPKSIYQV--PE---F-PCSPSTETAR-----LNSNTEKS--RDSST
GDDAPNQ-ETSHSLQEVDLNE---------V----T-VST------MVHDIDYQALKTLN
-LNPANTNNFHLATTEALALDTRKAVEVVNLSVSCTATCLPFSSMLKEAPAKVGLSSKQN
IFPITHQPVGSFGVVSCDTRNLEEEVNERMYS----FYQAKEKFKKELKNEECLYSDLSV
LASDLPYFPPEEEEEN

PF07819 // ENSGT00390000007885_1_Domain_2 (1457, 1700)

LEDGIHLVICVHGLDGNSADLRLVKTFIELGLPGGKLDFLMSER
NQ-SDTFADFDTMTDRLLDEIIQHIQLYNLS-ISRI--SFIGHSLGNII-IRSVLTRPRF
RYYLNKLHTFLSLSGPHLGTLYNNSTLVSTGLWLMQKLKKSGSLLQLTFRDNTDLRKCFL
YQLSQKTGLQYFKNVVLVASPQDRYVPFHSARIEMCKMALKDRHTGPVYVEMINNLLQPL
IEAKDCTVIRHNVFHALPNTANALIGRAAHIAVLDSELFLEKFF---LVT-GLNYFK---
---------

MSEIQGTVEFSVELHKFYNVDLFQRGYYQIRVTLKVSSRIPHRLSASITGQTESS----S
LHSACVHDSTVHSRVFQILYRNEEVPINDAVVFRVHLLLGGERMEDALSEVDFQ

PF12394 // ENSGT00390000007885_1_Domain_0 (115, 178)

LKVDLH
FTDSEQQ-LRDVAGAPMVSSRTLGLHFHPRNGLHHQVPVMFDYFHLSVISVTVHAAL

ENSGT00390000007885_1_Linker_0_1 (178, 323)

VAL
QQPLISFTRPGRGSWLGKGGPDTGQEQSIISLENLVFGAGYCKPTSS-EGSFYITSENCM
QHAHKWHRDLCLLLLHAYRGLRLHFLVIMRDIPELPHTEL-EALAVEETLSQLCSELQML
NNPEKIAE--QISKDLAWLTS-

PF12394 // ENSGT00390000007885_1_Domain_1 (323, 381)

HMMALWTQFLDTVTLHSQVTTYLTQEHHTLRVRRFSEA
F--FYMEHQKLAVLTFQENL

ENSGT00390000007885_1_Linker_1_2 (381, 1459)

IQTHSQLSLDIRNSEYLTSMPPLPAECLDIDGDWNTLPVI
FEDRYVDCPAT-GH--NL-------SVYP--NFDVPVT--SPTIMNLK------------
------------D-K----EV--NCMVNSNLSF--REDLV-LST--IKP--SQMD-----
---------------SDEEVIRCPETAENVAT-------QNHMNMCS---E---------
S-QVYISIGEFQNKAG-VP-------EDEC------------------------------
--------------WTGQTSDAGTYPMAD--------VDTSRRS---PGP----------
---------EDGQAPVLTYIDVKSSNKNPSRA-----EPLVAFNAQHESRSSRDKYGLDR
TGLSKVVVG--------GSHQNAISSDKTTLR--ELS---T--LGKGIDQEGK-------
----MVLLSLKLTP---SEPCDP-LSSTLREPLDIRSSLKDSHTEEQEELSVLSGVIKRS
SSVISDSGIESEPSSVAWSEARSRALELPSDREVLHPFVRRHALHRNSLEGGHTESNTSL
PSGIQASLTSISSLPFEEDEREVA-LTKLTKSVSAPHISSPEEAAEDAGTKKQDGGFAEP
SDMHSKN------QGSPGSCSQ-LCDDSG-----------------TQDA-GADHPLVE-
-IGLDAD----NQQGPGYIDIPKGKGKQSDAQEHC-----------------LPDSRTEN
T--PGVET----KGLNL-EIPRVIALENPRTRSLH---RALVETPKGMPKDL--NVGQPA
LSNSG--ISEVEGLSQ--HQV--PE---L-SCTSAA-----DAINMNSTGQQSQSDSPCI
MDDTAFN-R---------GVNAFPEAKHKAG----TVCPT------VTHSVHSQVLKNQE
LKAGTSIMGSHLTSAETFTLDSLKAVEVVNLSVSCTATCLPFSSVPKETPARAGFSSKQT
LFPITHQPLGSFGVVSTHSSTLDEEVSERMFS----FYQAKEKFKKELKIEGFLYSDLTV
LASDIPYFPPEEEEENLE

PF05057 // ENSGT00390000007885_1_Domain_2 (1459, 1657)

DGIHLVVCVHGLDGNSADLRLVKTFIELGLPGGKLDFLMSEK
NQ-MDTFADFDTMTDRLLDEIIQHIQLYNLS-ISRI--SFIGHSLGNII-IRSVLTRPRF
RYYLNKLHTFLSLSGPHLGTLYNNSTLVSTGLWLMQKLKKSGSLLQLTFRDNADLRKCFL
YQLSQKTGLQYFKNVVLVASPQDRYVPFHSARIEMCKTALKDRHTGPVYAEMINNLLGPL
VEAKDCTLIRHNVFHALPNTANTLIGRAAHIAVLDSELFLEKFF---LVA-GLNYFK---
---------

MSEVQGTVEFSVELHKFYNVDLFQRGYYQIRVTLKVSSRIPHRLSASIVGQTESS----S
LHSACVHESVVHSRIFQILYRNEEVSINDAMLFRVHLLLDGERVEDALSEVEFQ

PF12394 // ENSGT00390000007885_1_Domain_0 (115, 177)

LKVDLH
YTDSEQQ-LRDVTGTPMISSRTLGLHFHPRRGLHHQVPVMFDYFHLSVISVAIHAALVAL
QQPLISFTRPGRGSWLGKGGPDTGPEQPTISLENLVFGAGYCKPTTS-EGSFYVPSENCI
QHAHKWHRDVCLLLLHAYRGLRLYFLVIMRDIPELPTMEL-EVLAVEETLSQLCSELQML
NNPEKIAE--QISKDLAWLAS-HLMALWTQFLDTVTLHSHVTTYLTQEHHTLRVRRFSEA
F--FYMEHQKLAVLTFQENLIQTHSQLSMDIRNSEYLTSMPPLPAECLDIDGDWNTLPVI
FEDRYVDCPVS-GH--NL-------SVYP--NFEVPVT--SPAIMKLK------------
------------G-K----EK--S-VINQKSSS--RKEAP-LST--TEA--PELG-----
---------------SDEDVIQCPEMEENVST-------QNPMDVCS---E---------
S-QVYLSIGEFQNRAG-IP-------EDEC------------------------------
--------------WTGPRPDAVKDSLTD--------VDICRRS---PGP----------
---------EEGHTPALTYIDVESSNKNYPRA-----EPVLGLNVQHEPRGSRDSYGIVK
TMPSKVLAG--------ISQNNSISVNQTAAL--ELR---T--LGRGVGQEGK-------
----PVLLSLKLTP---AEPCDP-LSTGLREALDTKPSLP-DPGEEPEDLSVLSGVIKRS
ASIISDSGIESEPSSVAWSEARSRALEIPSDRDILHQVVRRHAHHRNSLEGGHTESNTSL
PSAIQASLSSISSLPFEDEERELA-LTKLTKSVSAPQISSPEDTAEDSDTIKNTAGFSED
LDLSSKD------NSSSRYSSP-SYSGSR-----------------VQDV-RAGHSLAD-
-IAVASD----RPQGPGYMDIHKGNENHPDLQGPC-----------------CLDAMAEN
I--PHVET----KGLNL-KIPCTTVLENPKTRSFH---RTAVETAKGKAKEL--SLSKHM
LSNNS--ISEVRAASH--HRV--PE---I-SCAPAV-----GAGHLHSTGVQNGS--LSV
NDTMTLN-R---------RHNASPEAKHEAG----TVCPT------VTHTIASPVSRNQE
LKAGTSISGSHLNSTEAFTLDSLKAVEVVNLSVSCTATCLPFSSVPKETPARAGLSSKQS
PAPITHQPLGSFGVVSTYSSELEEEVSERMFS----FYQAKEKFKKELKIEGFLYSDLSV
LASDIPYFPPEEEEENLE

PF05057 // ENSGT00390000007885_1_Domain_2 (1459, 1657)

DGIHLVVCVHGLDGNSADLRLVKTFIELGLPGGKLDFLMSEK
NQ-MDTFADFDTMTDRLLDEIIQHIQLYNLS-ISRI--SFIGHSLGNII-IRSVLTRPRF
RYYLNKLHTFLSLSGPHLGTLYNNSTLVSTGLWLMQKLKKSGSLLQLTFRDNADLRKCFL
YQLSQKTGLQYFKNVVLVASPQDRYVPFHSARIEMCKTALKDRHTGPVYAEMINNLLGPL
VEAKDCTLIRHNVFHALPNTANTLIGRAAHIAVLDSELFLEKFF---LVA-GLNYFK---
---------

--------------------------YYQIRVTLKVSSRIPHRLSASIVGQTDGG----S
LHSACVHESTVHSRVFQILYRNEEVPVNDAVVFRAHLLLDGERXXXXXXXXXXXXXXXXX
XXXXX-XXLRDVAGVPVISSRALRLHFHPRRGLHHQVPVMFDYFHLSVISVTVHAALVAL
QQPLISFTRPGRGSWLGRGGPDTGPEQSSLSLENLVFGAGYCKPTSSEXXXXXXXXXXXX
XXXXXXXXXXXXX-XX-XXXXXXXXXXXXXXXXXXXXXXXXXSLAVEETLSQLCSELQML
NNPEKIAE--QISKDLAWLAS-HLMALWTQFLDTVTLHSQVTTYLTQEHHTLRXXXXXXX
X--XXXXXXXXXXXXXXXXXIQTHSQMSLDIRNSEYLTTMPPLPAECLDIDGDWNTLPVI
FEDRYVDCPVT-GH--NL-------SVYP--NFDAPAT--SPAIMNVKDREE--------
-----------------------SHVVNRTSPL--TEDLV-LPT--MKP--PQMD-----
---------------SDEEVIRCPEPDENAAT-------PKCLGTRS-------------
ESQVYLTVGEFHSKAD-LP-------EDES------------------------------
--------------WSGRRPDVGARPLAD--------EDLPRRS---PSP----------
---------EDGQAPALTYIDVTSSNKEPRGA-----EPMVVLSAQHESGASLD-FSLGR
TELSKGVAG--------GSPQNAISLEKTTLH--ELS-----ALGKGADQGGG-------
----VALLSLRLTP---SEPCDP-LSASLRDPLDFRASPKDPLTE--EEVSVLLGSFKRS
SSLFSDSGIECEPSSVAWSEAPSLPLELP-DRDVLHQLV-IHALHRNSLEGGPTET-LNL
PSGNPASLXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------XXXXXXXXXXXXXXXX
XXXXXXXXX----XXXXXXXXX-XXXXXX-----------------XXXXXXXXXXXXX-
-XXXXXX----XXXXXXXXXXXXXXXXXXXXXXXX--------XX-XXX---XXXXXXXX
X--XXXXX-XXXXXXXX-XXXXXXXXXXXXXXXXX---XXXXXXXXXXXXXX--XXXXXX
XXXXX--XXXXXXXXX--XXX--XX---X-XXXXXXX-----XXXXXXXXXXX-X--XXX
XXXXXXXXX---------XXXXXXXXXXXXX-X--XXXXX------XX------XXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRAGFSSKQT
LFPITHQPLGSFGVVPTHSGKLEEEVSERMFS----FYQAKEKFKKELKIDGFLYSDLSV
LASDMPYFPPEEEEEN

PF05057 // ENSGT00390000007885_1_Domain_2 (1457, 1658)

LEDGIHLVVCVHGLDXXXXXXXXXXXXXXXXXXXXXXXXXXX-X
XXXTDTFADFDTMTDRLLDEIIQHIQLYNLS-ISRIXXXXXXXXXXXXXXX---XXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLWLMQKFEESGSLLQLTFRDTD--LRCFL
YQLSXXXXLQYFKNVVLVASPQDRYVPFHSARIEMCKTALKDRHTGPVYAEMINNLLRPL
VEAKGCTLVRHNVFHALPNTANTLIGRAAHIAVLDSELFLEKFF---LVA-GLNYFK---
---------

MSEIQGTVEFSVELHKFYNVDLFQRGYYQIRVTLKVSSRIPHRLSASIAGQTESS----S
LHSACVHDSTVHSRVFQILYRNEEVPINDAVVFRVHLLLGGERMEDALSEVDFQ

PF12394 // ENSGT00390000007885_1_Domain_0 (115, 178)

LKVDLH
FTDSEQQ-LRDVAGAPMVSSRTLGLHFHPRNGLHHQVPVMFDYFHLSVISVTVHAAL

ENSGT00390000007885_1_Linker_0_1 (178, 323)

VAL
QQPLISFTRPGRGSWLGKGGPDTGQEQSIISLENLVFGAGYCKPTSS-EGSFYITSENCM
QHAHKWHRDLCLLLLHAYRGLRLHFLVIMRDIPELPHTEL-EALAVEETLSQLCSELQML
NNPEKIAE--QISKDLAWLTS-

PF12394 // ENSGT00390000007885_1_Domain_1 (323, 381)

HMMALWTQFLDTVTLHSQVTTYLTQEHHTLRVRRFSEA
F--FYMEHQKLAVLTFQENL

ENSGT00390000007885_1_Linker_1_2 (381, 1459)

IQTHSQLSLDIRNSEYLTSMPPLPAECLDIDGDWNTLPVI
FEDRYVDCPAT-GH--NL-------SVYP--NFDVPVT--SPTIMNLK------------
------------E-K----ED--NCMVNGNLSF--REDLV-LST--IKP--SQMN-----
---------------SDEEVIRCPELAENVAT-------QNHMDVCS---E---------
S-QVYITIGEFQNKAR-VP-------EDEC------------------------------
--------------WTGQTSDAGTYPMAD--------VDTSRKS---PGS----------
---------EDGQAPVLTYIDVKSSNKNPSRA-----EPLVAFNAQHENRSSRDKCGLDR
TGLSKVVVG--------GSHQNAISSDKTTLH--ELS---T--LGKGIDQEGK-------
----MVLLSLKLTP---SEPCDP-LNSTVREPLDIRSSLKDSHTEEQEELSVLSGVIKRS
SSIISDSGIESEPSSVAWSEARSRALELPSDREVLHPFVRRHALHRNSLEGGHTESNTSL
PSGIQASLTSISSLPFEEDEREVA-LTKLTKSVSAPHISSPEEAAEDADTKQQGGGFAEP
SDMHSKS------QGSPGPCSQ-LSGDSG-----------------TQGA-AADPPLVE-
-IVLDAD----NQQGPGYIDIPKGKGKQFDAQGHC-----------------LPDGRTEN
T--PGVET----KGLNL-RIPRVMALENPRTRSLP---RALVETPKGIPKDL--NVGQPA
LSNSG--ISEVEGLSQ--HQV--PE---L-SYTSAA-----DAINMNSTGQQSQSGSPCI
MDDTAFN-R---------GVNAFPEAKHKAG----TVCPT------VTHSVHSQVLKNQE
LKAGTSIMGSHLTSAETFTLDSLKAVEVVNLSVSCTATCLPFSSVPKETPARAGFSSKQT
LFPITHQPLGSFGVVSTHSSTLDEEVSERMFS----FYQAKEKFKKELKIEGFLYSDLTV
LASDIPYFPPEEEEENLE

PF05057 // ENSGT00390000007885_1_Domain_2 (1459, 1657)

DGIHLVVCVHGLDGNSADLRLVKTFIELGLPGGKLDFLMSEK
NQ-MDTFADFDTMTDRLLDEIIQHIQLYNLS-ISRI--SFIGHSLGNII-IRSVLTRPRF
RYYLNKLHTFLSLSGPHLGTLYNNSTLVSTGLWLMQKLKKSGSLLQLTFRDNADLRKCFL
YQLSQKTGLQYFKNVVLVASPQDRYVPFHSARIEMCKTALKDRHTGPVYAEMINNLLGPL
VEAKDCTLIRHNVFHALPNTANTLIGRAAHIAVLDSELFLEKFF---LVA-GLNYFK---
---------

MSEVQGTVEFSVELHKFYNVDLFQRGYYQIRVTLKVSSRIPHRLSASIVGQTDSS----S
PHSACVHDSTLRSRVFQILYRNEEVPINDAVIFRAHLLLDGERVEEAVSEVDFQ

PF12394 // ENSGT00390000007885_1_Domain_0 (115, 178)

LKVDLH
FTDSEQQ-LRDMAGVPVISSRVLGLHFHPRRGLHHQVPVMFDYFHLSVISVTIHAALVAL
QQPLISFTRPGRGSWLGKGGPDTGPEQSSLSLENLVFGAGYCKPTSS-EGSFYVPSENCM
QHAYKWHRELCFLLLHAYRGLRAYFLTILRDIPELPRMEL-ESLAVEETLSQLCSELQVI
REPTPWF-----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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---------

MSEVQGTVEFSVELHKFYNVDLFQRGXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----X
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXFTRPGRGSWLGKGGPDTGPDQSSISLENLVFGAGYCKPTSS-EGSFYVPSENCM
QHAHKWHRGLCQLLLHAYHGLRAYFLLVMRDVPELPRMEL-EALAVEETLSQLCSELQXX
XXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXX---XXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXIQTHSQLSLDVRNSEYLASMPPLPAECPDIDGDWSTLPVI
FEDRYVDRTAAXXXXXXXXXXXXXXXXXX-----XXXX----XXXXXX-X----------
------------X-X----XX--XXXXXXXXXX---------X-----------------
-------XXXXXXXXXXXXXXXXXDAGENVT--------SNHADLCS---V---------
S-QVYLTIGEFQSKAA-SP-------KEEC------------------------------
--------------RTGQRSEVGTHPLAD--------VDMSTKS---LGP----------
---------ADGQVPGLTYIDVKSSPKDSCRAEPAVVEPTMVLNAQSGTGASGDSYGLDR
TVLSKMAAG--------GRCHSAISSGKITLL--ELN---P--PGK-RVEEGK-------
----VLLLGLKPAP---SEPCDP-LSSALRDPLDVRASLKDPPTEEQEEVLGLSGIIKRS
SSIISDSGIESEPSSVAWSDARSRALDLPSDREVLHHLVRRHALHRNSLEGGHTESNTSL
PSGTQASLTSITSLPFEEEERELA-LTKLTKSVSAPQISSPEESAEDTDTIQQGGGLAEA
LDMHTKS------RDSPENCSQ-LCGDSR-----------------T-RDAEVDHSLVE-
-TALDAD----DAQDPAYIDIPKGKDDQFGPQGHC--------SL---------DSRTGK
S--PGVDT----KGLDI-KIPRIIALEKPRDRSFH---RTLLETSMGLPTDS--NVEERA
QSNTS--ASGVEDLAH--HKV--PV---S-SCASVAS-----SDDLNPTGDPR--GFPCI
TDDTVLT-R---------GDNTSPGTGREAG----TMCPT------VTPFTHALESENQE
LKAGTSSLVSPLNVPETFPLDSLKAVEVVNLSVSCAATCLPFSSVLKETPAGAGFSSKQA
PFPITHQPLGSFGTVSTHASRLEGEVSDRMFS----FYQAKEKFKKELKIEGFLYSDLSV
LASDVPYFPPEEEEEN

PF05057 // ENSGT00390000007885_1_Domain_2 (1457, 1658)

LEEGIHLVVCVHGLDGNSADLRLVKTFIELGLPGGKLDFLMSEK
NQ-MDTFADFDTMTDRLLDEIIQHIQLYNLS-ISRI--SFIGHSLGNII-IRSVLTRPRF
RYYLNKLHTFLSLSGPHLGTLYNSSTLVSTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXLQYFKNVVLVASPQDRYVPFHSARIEMCKTALKDRHTGPVYAEMINNLLRPL
VEAKDCTLIRHNVFHALPNTANTLIGRAAHIAVLDSELFLEKFF---LVA-GLNYFK---
---------

------------------------------------------------------------
---ACVHENNVYSRIFQILYRNEEIILNESMNFRVHLLLDGERVEDALSEADFQLKLDLH
FTDSEQQ-LRDVPAIPMISSRTLCLHFHPQRGLHHHVPVMFDYFHLSVISVTVHASLVAL
HQPLISFARPGKGSWLGKGNLDTGPDQSSMSLENLVFGAGYCKPTSS-EGSFYVPSENCM
QHAYKWHKDLCLLLLNAQRGLHVYYTLIMKEVPDLPQLKL-EELPVEDTLSQFCAELQLL
SNPEKIAE--QISKDLSWLCS-HLLALWTQFLEVATLHPEVTAYLTQEHHMLRVRRFSEA
F--FYTEHNKLAVLTFQEGLIQSHAQISTEIRNSEYFTNMPPLPAECLDIDGDWNTLPVI
FEDRYMDLPCKERK--KNWIFVTLTNRAT--NFIPRVT--SSVKKSQNKKPYSFCEDQHC
PHKAVLLFLKIISPRVPRFII--KKIFSSATRK--YKLLV--------------FASFFF
LSNYLSVLETSSLDNINQNLDS--FPDFEAPANTQIDTIHEKENLAS---N---------
D-DTVEMKGDFGKGTL-LI-------HTDRINGN-PCLY-----SDSKGV-----AFAAK
SLNQHSTSQVCTANKEGQKIPENIYVSSK--------ETTSVSE---LSNTECISEESKT
C--KEVLLRDSRHSVGITSEEKKSSNKGAHKS-----EPVLIVSAQIECGACGTDGLEGR
TEIHKMTES--------GHPENNFSSELALSE---FTR-----LERIPDADS--------
------------------KPLQPVL------------------------KALPSHSLERS
SSIISDSGIESEPSSVAWSDARSRALELPSDREILHHLVRRHAIHRNSLEGGHTESNTSL
PSGIQASLTSISSLPFEEEIEAT----------------------------------SRD
SGGYLKSCRETENGDGQSMIDFSMC---Q-----------------LTTKSGQLEPREP-
-PKP--S----AKNRNDNIE-LQREAKEDFSETYC--------SLECAKPPACNP-LRDN
D--SECQSLESNDGCSL-KTPRANNYLDKSIDEFD----KYITDPKDTSKPDSLKIEQNL
YIN--VRKTGEDSFSQSIKLV--PH---I--CNPVSGPSETSTEFGSMQEECNSF----L
ADESLLVYA---------EMQGLQEIELNDSLA--SADPAA----ESCQDKYPQELDNQG
QKLVANGTGFHSVTMDGVTLESRKAVDVVNLSVSCTATCLPFSSVLKETPAMVGFSAKQA
AFPITRQPLGSFGVVSSHSNEVDEEANERMLN----FYQAKEKFKKEMKIEGFLYSDLSV
LASDIPYFPPEEEEEN

PF05057 // ENSGT00390000007885_1_Domain_2 (1457, 1658)

LEDGIHLVVCVHGLDGNSADLRLVKTFIELGLPSGKLDFLMSER
NQQTDTFADFDTMTDRLLDEIIQHIQLYNLS-ISRI--SFIGHSLGNVI-IRSVLTRPRF
RYYLNKLHTFLSLSGPHLGTLYNNSTLVSTGLWLMQKLKKSGSLLQLTFRDNADLRKCFL
YQLSQKTGLQYFKNVVLVASPQDRYVPFHSARIEMCKNALKDRHTGPVYAEMINNLLQPL
IGAKDCTLIRHNVFHALPNTANTLIGRAAHIAVLDSELFLEKFF---LVA-GLNYFK---
---------

------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------MPPLPAECLDIDGDGNTVPVI
FEDRYVDSPYK-SQ--SL-------DVFP--AFEVPVM--NGAQMDLINSKE--------
-----------------------ALASNEDISL--EKADFRKDTLFIHT--DKIN-----
--------------G----NASCIYSDIATET-------YVAKDLAQ-HST---------
S-QTSPVNKEVQRKTD-VSHENVSISSSEM------------------------------
--------------VSGLDTGLLKHKAGD--------FQMPV-----DIP----------
---------LKDDRLGVECMDVKLSNKDCHKG-----EPILIISALCDSGTRGLL---DT
TELRQAAKT--------DDNEHILTSDELALN--ELN---S--LERPVEQDNK-------
----ALLPALKALP---ISTLDL-LTQTTKDAPEGKSSVKEQRTEECEEFTLSSGVIKRS
SSIISDSGIESEPSSVAWSDVRSRALELPSDREMLQQLVRRHTLHRNSLEGGHTESNTSL
PSGIQASLTSISSLPFEEEEREVE-LTKLTKSVSAPQISSPEEPTDNIAMPQGDKAILEV
AEGPLKSSMGVMCRSTDMPGRFSECENATDSEQTEPDIATGEHPRAAVKQRNSSNELPE-
-EEADKEGFAEGACSSEYAGQPVNVKQHRCDPSEC------------------QAGQRNE
E--CSLET----QNVRPSSDPRDV------HFSAY---SDLKDALNPMPKEL--QIGEDF
YSSVS--ILDIENFSHGVSRV--PD---F-CYTFPASSET--STEFGSTRGEC--GSPFP
NEPMVSC-EEMQGLQEIELDDASALADLGDG----SYCAE------YPQELE-----RVE
GQLMANGTGVQSAATEGLALESRKAVEVVNLSVSCTATCLPFSSVLKETPAVVGFSSKQA
TFPITRQPLGSFSVVACNSDDMDEEANERMLS----FYQAKEKFKKEMKIEGFLYSDLSV
LASDIPYFPPEEEEENLE

PF05057 // ENSGT00390000007885_1_Domain_2 (1459, 1657)

DGIHLVVCVHGLDGNSADLRLVKTFIELGLPGGKLDFLMSER
NQ-SDTFADFDTMTDRLLDEIIQHIQLYNLS-ISRI--SFIGHSLGNVI-IRSVLTRPRF
RYYLNKLHTFLSLSGPHLGTLYNNSTLVSTGLWLMQKLKKSGSLLQLTFRDNADLRKCFL
YQLSQKTGLQYFKNVVLVASPQDRYVPFHSARIEMCKTALKDRHTGPIYAEMINNLLQPL
VGAKDCTLIRHNVFHALPNTANTLIGRAAHIAVLDSELFLEKFF---LVA-GLSYFK---
---------

MSEVQGTVEFSVELHKFYNVDLFQRGYYQIRVTLKVSSRIPHRLSASIAGQTDSS----S
LHSACAHENVVHSRVFQILYRNEEVPINDAVIFRAHLLLDGERVEEALSEVDFQ

PF12394 // ENSGT00390000007885_1_Domain_0 (115, 178)

LKVDLH
FTDSEQQ-LRDVAGAPLISSRTLGLHFHPRRGLHHQVPVMFDYFHLSVISVTIHAAL

ENSGT00390000007885_1_Linker_0_1 (178, 323)

VAL
QQPLISFTRPGRGSWLGKGGPDTGPEQSSLSLENLVFGAGYCKPTSS-EGSFYVPSENCM
QHAHRWHRDLCFLLLHAYRGLRAYFLVIMRDIPELPHMEL-ESLGVEETLSQLCSELQML
NNPEKIAE--QISKDLAWLTS-

PF12394 // ENSGT00390000007885_1_Domain_1 (323, 381)

HLMALWTQFLDTVTLHSQVTTYLTQEHHTLRVRRFSEA
F--FYMEHQKLAVLTFQENL

ENSGT00390000007885_1_Linker_1_2 (381, 1459)

IQTHSQLSLDIRNSEYLTTMPPLPAECLDIDGDWNTLPVI
FEDRYVDCPAT-GC--NL-------SVYP--NFDVPT---SPAIMNLK------------
------------D-T----EE--NAIINRKSPF--REDLV-LPT--MKP--LQMD-----
---------------SDEEVTRCPEPDNSITT-------PKHVDVCS---K---------
S-QVYLTIGEFQNKAD-LP-------EDEC------------------------------
--------------WTGQRSDVGTHPLAD--------EDLPRRS---PGP----------
---------EDGQAPVLTYIDVKSSNKKPCSA-----EPTVVISAQHESGHSQDNYESDR
TVPGKDIAG--------GSRPNAIILEKTTLH--ELS---T--LGKVADQEGK-------
----VVLLSLKLIP---SEPCDP-LNSTLRDPLDVRASPKDPHAEEQEEVSVLSGVIKRS
SSIISDSGIESEPSSVAWSEARSRALELPSDREVLHHLVRRHALHRNSLEGGHTESNTSL
PSGIQASLTSISSLPFEEEERELA-NTKLTKSVSAPQISSPEESSEDTDTMQQRGGLAER
SAIPIKS------IDSPGAGTD-SFP-------------------------------GQ-
-VVSGAD----NQQGPGYIDIPKGKDSQFDPQGPC-----------------CLDGRTEN
P--PDIET----KGLNL-EIPRVIALENPQNGSCP---GVLMETPKGMPEDL--NVEKGA
LSDSS--ISDDETVAH--HKV--PE---W-SCTAAA-----NASDLGSTGEQS--SSPCI
IDDAAFS-K---------GSQAPLEAGHEAG----TVCST------VTHSINSQLLGTQE
PRAVTSVMVSHLTPAETFTLDSLKAVEVVNLSVSCTATCLPFSSVPKETPARAGFASKQT
PLPITHQPLGSFGVVSAHSSKLEEEVSERMYS----FYQAKEKFKKELKIDGFLYSDLSV
LASDIPYFPPEEEEENLE

PF05057 // ENSGT00390000007885_1_Domain_2 (1459, 1657)

DGIHLVVCVHGLDGNSADLRLVKTFIELGLPGGKLDFLMSEK
NQ-MDTFADFDTMTDRLLDEIIQHIQLYNLS-ISRI--SFIGHSLGNII-IRSVLTRPRF
RYYLNKLHTFLSLSGPHLGTLYNNSTLVSTGLWLMQKLKKSGSLLQLTFRDNADLRKCFL
YQLSQKTGLQYFKNVVLVASPQDRYVPFHSARIEMCKTALKDRHTGPVYAEMINNLLRPL
VEAKDCTLIRHNVFHALPNTANALIGRAAHIAVLDSELFLEKFF---LVA-GLNYFK---
---------

---------------------------------------------------------SSS
PHSACVHENTVLGRVFQILYRNEEVPINDAVIFRAHLLLDGERVEDALSEVDFQLKVDLH
FTDSEQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXX
-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGSFYVPSENCM
QHAYKWHRDLCHLLLNAHRGLRAYFLVIMRDIPELPHMEL-EALAVEETLSQLCSELQML
NNPEKIAE--QISKDLAWLAS-HLMALWTQFLDTVTLHSQVTTYLTQEHHTLRVRRFSEA
F--FYMEHQKLAVLTFQENLXXXXXXXX--------------------------------
-------------X----------------------XX---------X------------
-----------------------------------------XXX---XX-----------
--------------------------------------------------X---------
X--------------X-XX--------XXX------------------------------
---------------------------XX--------------X----------------
-----------------------------XXX----------------------------
------XXX--------------------XXX--XXX---------------X-------
------------------------------------------------------------
--------------------------------------------------------XXXX
XXXXXXSLTSISSLPFEEEERELA-LTKLTKSVSAPQISSPEEAAEETDTRQRGGGLE-A
PEMHVQG------TDSPGNCSQ-LCGGSIIQ------------------DAGAAHSLAE-
-IILDAG----DHQGPSYIDIPKGKESQVDPQRPC-----------------SLDGRTED
P--PGVET----KG--LLTIPHLIALETPGNRSFH---RALLETPEGMPKDL--NMGKGA
LSSSS--MSDVEDVSP--HQV--PE---L-SCPPAVEAIE-----LDPQ---QQNDLPCI
TDATVFN-R---------AADAFPELEPKAE----TVCPT------GTHSIYSQVSGNQE
PNSGPSVMAPPL-PPETFPLTSPKAVSVL------VCACLPFSSXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXX----XXXXXXXXXXXXXXXFYQAKEKFKKELKIEGFLYSDLTV
LASDIPYFPPEEEEEN

PF05057 // ENSGT00390000007885_1_Domain_2 (1457, 1658)

LEDGIHLVVCVHGLDGNSADLRLVKTFIELGLPGGKLDFLMSEK
NQ-TDTFADFDTMTDRLLDEIIQHIQLYNLS-ISRIXXXXXXXXXXXXXXX---XXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLWLMQKLKKSGSLLQLTFRDNADLRKCFL
YQLSQKTGLQYFKNVVLVASPQDRYVPFHSARIEMCKTALKDRHT---------------
------------------------------------------------------------
---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------FTRPGRGSWLGKGGPDTGQEQSIISLENLVFGAGYCKPTSS-EGSFYVPSENCM
QHAHKWHRDLCLLLLHAYQGLRLYFLLIMRDIPELPHTEL-EALAVEETLSQLCSELQML
NNPEKIAE--QISKDLAWLAS-HMMALWTQFLDVVTLHSQVTTYLTQEHHSLRVRRFSEA
F--FYMEHQKLAVLTFQENLIQTHSQLSLDIRNSEYLSSMPPLPAECLDIDGDWNTLPVI
FEDRYVDCPAT-GH--NL-------SVYP--DFDVPGT--SPTIMDLK------------
------------D-K----EE--KRILNSNLSF--REDLV-LST--MKS--PQRD-----
---------------SDEEVTRCPEPDEKVTT-------QNHVNMCP---E---------
S-QVYLTIGELQNKTG-IP-------EDEC------------------------------
--------------WTGQRSDVGTYPLAD--------ADI-SRN---PGP----------
---------EDGQAPALTYIDVKSSNKNPYRA-----EPTVVINAQHENKSSRDTHGLDR
TEQSKVVAG--------GTHQNA--SDKTVVH--ELS---T--VGKGRDQESK-------
----MVLLSLKLNP---AEPCDP-LNSTPREPLDIKSSLKDSHTEEQEELSVLSGVIKRS
SSIISDSGIESEPSSVAWSEARSRVLELPSDREVLQPFVRRHALHRNSLEGGHTESNTSL
PSGIQASLTSISSLPFEEDEQELA-LTKLTKSVSAPHISSPEDAAEDTDTMQPGEGFTEP
SDTHSKS------KDSPEHCSQ-LCGGSR-----------------IQDT-VIDHSLVE-
-IILDAD----SQQGPGYIDIPKGKERQSDPQEHC-----------------CLDGRTEN
T--PGVET----KALNL-KIPCIVALENSRTRILH---KALMETPKSMPKDL--NKGQLA
LSNSG--ISEVKGLSH--HQV--PE---L-SCRSST-----DAINMNSTGEQRRSGSPCV
TDDTAFS-R---------EANAFPEVEYKAD----TVCPT------VTHSTHSQVLRNQE
PKADTSVLESQVTSTETFSMDTLKAVEVLNLSVSC--TCLPFSSVPKKTPAMAGFSSKQT
PFPITHQPLGSFGLVSTHSSKLEKEVSERMFG----FFQAKEKFKRELKIEGFLYSDLTV
LASDIPYFPPEEEEENLE

PF05057 // ENSGT00390000007885_1_Domain_2 (1459, 1657)

DGIHLVVCVHGLDGNSADLRLVKTFIELGLPGGKLDFLMSEK
NQ-MDTFADFDTMTDRLLDEIIQHIQLYNLS-ISRI--SFIGHSLGNII-IRSVLTRPRF
RYYLNKLHTFLSLSGPHLGTLYNNSTLVSTGLWLMQKLKKSRSLLQLTFRDNADLRKCFL
YQLSQKTGLQYFKNVVLVASPQDRYVPFHSARIEMCKTALKDRQTGPVYAEMINNLLGPL
VEAKDCTLIRHNVFHALPNTANTLIGRAAHIALLDSELFLEKFF---LVT-GLNYFK---
---------

MSEVQGTVDFSVELHKFHNVDLFQRGYYLVHASLKVPSRIPHRVLATIVEQTGNS----I
LCSACVQDNSVYSRVFQILYRNEEIVINESMNFRVHLLLDGEKVEEALCEADFQ

PF12394 // ENSGT00390000007885_1_Domain_0 (115, 178)

LKLDLQ
FTDSEQQ-LRDVSTIPVISSRTLGLHFHPKQGLHHHVPVMFDYFHLSAISVTLHASL

ENSGT00390000007885_1_Linker_0_1 (178, 325)

VAL
HQPLISFTRPGKGTWLGKGNMEMGPDLTGMSLENLVFGAGYCKPAAS-EGSFYVPSENCM
QHAHKWHRDLCFMLLNAYRGLHVYYAFIKKEIPTLPQLKL-EDLAVEETLSQLSAELQML
NNPEKIAE--QISKDLAWLCS-HL

PF12394 // ENSGT00390000007885_1_Domain_1 (325, 381)

LALWTQFLEIVTLHPDVTTSLVQEHHTLRVRRFSEA
F--FYAEHQKLAALTFQESL

ENSGT00390000007885_1_Linker_1_2 (381, 1464)

IQHHNQVSSEVRNSEYLTSMPPLPAECLDIDGDWSTLPII
FEDRYVEFPYEVQDLDIL----------S--NDVSSAV--GNSQVDLDKNG---------
-----------------------DPSSNTD------------------------------
------------------------------------------------------------
---TALAKRDFRNDVPFII-------HTDRINGKPLYSC----NSNPQGD-----CSIVK
SSKDHSATQVQAMSGSIPAHENQV-KLAS----DGLKLDL----------LKDSSESLNT
P--IEFSEKNNRLKTEVEYLDMHPICNSTHQR-----EPMLVMTSMYDGITYEQLQHIER
TKLRQENNNDYCGST---VISDKFSSEEQNI------------CEKQCDHCDE-------
----SVLPALKGFEA--NEQFG--SLNQIKNVEGVKSFQQEQRVQECEEFSSRSGAIKRS
SSLISDSGIESEPSSVAWSDARSKVLDLPSDREILHQLVRRHAAHRNSLEGRHTESNTSL
PSGIQASLTSISSLPYEEEEGEVE-PNKLTKSISAPQISSPEETVEDMNISKHIQTIADI
AEGPYVE---IGYASMTLMEKNSTCQKAG-------------------EHEGLPLSIAA-
-VKHSQS---SFEQNDDSSQHP--KVFEGVSEVNC--------TLETAGVTVILKQNQDS
GYTPEHQLTNKNREDNL----------GSINDHLD---RSIIHLGE-------YTDNVNM
YKGHSLYSKDVQAFSGCETNV--PD---F-TCTMHVSS----VVASGSSSTKGPYSSPLT
NGKIAACGE---------VIHNLQEIELDNTSESGTSCAE--------------SEKNEL
KRVSSNSSGLHSVVPETLVLESKKAIEGVNLSVSCTATCLPFSSVLKESPPTAGFSSKQV
TSPITHQPVGSFGVISSDSSDVDEETNERMVS----FYQAKEKFKKELKTEGYLYSDLPV
LSSDIPYFPPEEEEEDLEDGIHL

PF07819 // ENSGT00390000007885_1_Domain_2 (1464, 1588)

VVCVHGLDGNSADLRLVKTFIELGLPGGKLDFLMSER
NQ-TDTFADFDTMTDHLLDEIIQHIQLYNLT-ISRI--SFIGHSLGNII-IRSVLTRQRF
RYYLNKLHTFLSLSGPHLGTLYNNSTLVSTGLWLMQKLKKSGSLLQLTFRDNTDLRKCFL
YQLSQKTGLQYFKNVVLVASLQDRYVPFHSARIEMCKPALKDRHTGPVYAEMINNLLQPV
IGAKDCTLIRHDVFHALPNTANTLIGRAAHIAVLDSELFLEKFF---LVA-GLNYFK---
---------

MSEIQGTVEFSVELHKFYNVDLFQRGYYQIRVTLKVSSRIPHRLSASIAGQTESS----S
LHSACVHDSTVHSRVFQILYRNEEVPINDAVVFRVHLLLGGERMEDALSEVDFQ

PF12394 // ENSGT00390000007885_1_Domain_0 (115, 177)

LKVDLH
FTDSEQQ-LRDVAGAPMVSSRTLGLHFHPRNGLHHQVPVMFDYFHLSVISVTVHAALVAL
QQPLISFTRPGRGSWLGKGGPDTGQEQSIISLENLVFGAGYCKPTSS-EGSFYITSENCM
QHAHKWHRDLCLLLLHAYRGLRLHFLVIMRDIPELPHTEL-EALAVEETLSQLCSELQML
NNPEKIAE--QISKDLAWLTS-HMMALWTQFLDTVTLHSQVTTYLTQEHHTLRVRRFSEA
F--FYMEHQKLAVLTFQENLIQTHSQLSLDIRNSEYLTSMPPLPAECLDIDGDWNTLPVI
FEDRYVDCPAT-GH--NL-------SVYP--NFDVPVT--SPTIMNLK------------
------------E-K----AD--NCMVNGNLSF--REDLV-LST--IKP--SQMD-----
---------------SDEEVIKCPELAENVAT-------QKHMDVCS---E---------
S-QVYITIGEFQNKTG-VP-------EDEC------------------------------
--------------WTGQTSDAGTHPMAD--------VDTSRRS---PGP----------
---------EDGQAPVLTYIDVKSSNKNPSRA-----EPLVAFNAQHENRSSRDKYGLDG
TGPSKVVVG--------GSHQNAISSDKTTLH--ELS---T--LGKGIDQEGK-------
----MVLLSLKLTP---SEPCDP-LNSTVREPLDIRSSLKDSHTEEQEELSVLSGVIKRS
ASIISDSGIESEPSSVAWSEARSRALELPSDREVLHPFVRRHALHRNSLEGGHTESNTSL
PSGIQASLTSISSLPFEEDEREVA-LTKLTKSVSAPHISSPEEAAEDADTKQQGGSFAEP
SDMHSKS------QGSPGPCSQ-LSGDSG-----------------TQDA-GADHPLVE-
-IVLDAD----NQQGPGYIDIPKGKGKQFDAQGHC-----------------LPDGRTEN
T--PGVET----KGLNL-KIPRVIALENPRTRSLP---RALVETPKGIPKDL--NVGQPA
LSNSG--ISEVEGLSQ--HQV--PE---L-SYTSAA-----DAINMNSTGQQSQSGSPCI
MDDTAFN-R---------GVNAFPEAKHKAG----TVCPT------VTHSVHSQVLKNQE
LKAGTSIMGSHLTSAETFTLDSLKAVEVVNLSVSCTATCLPFSSVPKETPARAGFSSKQT
LFPITHQPLGSFGVVSTHSSTLDEEVSERMFS----FYQAKEKFKKELKIEGFLYSDLTV
LASDIPYFPPEEEEENLE

PF05057 // ENSGT00390000007885_1_Domain_2 (1459, 1657)

DGIHLVVCVHGLDGNSADLRLVKTFIELGLPGGKLDFLMSEK
NQ-MDTFADFDTMTDRLLDEIIQHIQLYNLS-ISRI--SFIGHSLGNII-IRSVLTRPRF
RYYLNKLHTFLSLSGPHLGTLYNNSTLVSTGLWLMQKLKKSGSLLQLTFRDNADLRKCFL
YQLSQKTGLQYFKNVVLVASPQDRYVPFHSARIEMCKTALKDRHTGPVYAEMINNLLGPL
VEAKDCTLIRHNVFHALPNTANTLIGRAAHIAVLDSELFLEKFF---LVA-GLNYFK---
---------

MSEIQGTVEFSVELHKFYNVDLFQRGYYQIRVTLKVSSRIPHRLSASIAGQTESS----S
LHSACVHDSTVHSRVFQILYRNEEVPINDAVVFRVHLLLGGERMEDALSEVDFQ

PF12394 // ENSGT00390000007885_1_Domain_0 (115, 177)

LKVDLH
FTDSEQQ-LRDVAGAPMVSSRTLGLHFHPRNGLHHQVPVMFDYFHLSVISVTVHAALVAL
QQPLISFTRPGRGSWLGKGGPDTGQEQSIISLENLVFGAGYCKPTSS-EGSFYITSENCM
QHAHKWHRDLCLLLLHAYRGLRLHFLVIMRDIPELPHTEL-EALAVEETLSQLCSELQML
NNPEKIAE--QISKDLAWLTS-HMMALWTQFLDTVTLHSQVTTYLTQEHHTLRVRRFSEA
F--FYMEHQKLAVLTFQENLIQTHSQLSLDIRNSEYLTSMPPLPAECLDIDGDWNTLPVI
FEDRYVDCPAT-GH--NL-------SVYP--NFDVPVT--SPTIMNLK------------
------------E-K----ED--NCMVNGNLSF--REDLV-LST--IKP--SQMD-----
---------------SDEEVIKCPELAENVAT-------QKHMDVCS---E---------
S-QVYITIGEFQNKTG-VP-------EDEC------------------------------
--------------WTGQTSDAGTHPTAD--------VDTSRRS---PGP----------
---------EDGQAPVLTYIDVKSSNKNPSRA-----EPLVAFNAQHENRSSRDKYGLDR
TGPSKVVVG--------GSHQNAISSDKTTLH--ELS---T--LGKGIDQEGK-------
----MVLLSLKLTP---SEPCDT-LNSTVREPLDIRSSLKDSHTEEQEELSVLSGVIKRS
SSIISDSGIESEPSSVAWSEARSRALELPSDREVLHPFVRRHALHRNSLEGGHTESNTSL
PSGIQASLTSISSLPFEEDEREVA-LTKLTKSVSAPHISSPEEAAEDADTKQQGGSFAEP
SDMHSKS------QGSPGPRSQ-LSGDSG-----------------TQDT-GEDHPLVE-
-IVLDAD----NQQGPGYIDIPKGKGKQFDDQGHC-----------------LPDGRTEN
T--PGVETK--TKGLNL-KIPRVIALENPGTRSLP---RALVETPKGIPKDL--NVGQPA
LSNSG--ISEVEGLSQ--HQV--PE---L-SYTSAA-----DAINMNSTGQQSQSGSPCI
MDDTAFN-R---------GVNAFPEAKHKAG----TVCPT------VTHSIHSQVLKNQE
LKAGTSIMGSHLTSAETFTLDSLKAVEVVNLSVSCTATCLPFSSVPKETPARAGFSSKQT
LFPITHQPLGSFGVVSTHSSTLDEEVSERMFS----FYQAKEKFKKELKIEGFLYSDLTV
LASDIPYFPPEEEEENLE

PF05057 // ENSGT00390000007885_1_Domain_2 (1459, 1657)

DGIHLVVCVHGLDGNSADLRLVKTFIELGLPGGKLDFLMSEK
NQ-MDTFADFDTMTDRLLDEIIQHIQLYNLS-ISRI--SFIGHSLGNII-IRSVLTRPRF
RYYLNKLHTFLSLSGPHLGTLYNNSTLVSTGLWLMQKLKKSGSLLQLTFRDNADLRKCFL
YQLSQKTGLQYFKNVVLVASPQDRYVPFHSARIEMCRTALKDRHTGPVYAEMINNLLGPL
VEAKDCTLIRHNVFHALPNTANTLIGRAAHIAVLDSELFLEKFF---LVA-GLNYFK---
---------

MSEIQGTVEFSVELHKFYNVDLFQRGYYQIRVTLKVSSRIPHRLSASIAGQTESS----S
LHSACVHDSTVHSRVFQILYRNEEVPINDAVVFRVHLLLGGERMEDALSEVDFQ

PF12394 // ENSGT00390000007885_1_Domain_0 (115, 177)

LKVDLH
FTDSEQQ-LRDVAGAPMVSSRTLGLHFHPRNGLHHQVPVMFDYFHLSVISVTVHAALVAL
QQPLISFTRPGRGSWLGKGGQDTGQEQSIISLENLVFGAGYCKPTSS-EGSFYITSENCM
QHAHKWHRDLCLLLLHAYRGLRLHFLVIMRDIPELPHTEL-EALAVEETLSQLCSELQML
NNPEKIAE--QISKDLAWLTS-HMMALWTQFLDTVTLHSQVTTYLTQEHHTLRVRRFSEA
F--FYMEHQKLAVLTFQENLIQTHSQLSLDIRNSEYLTSMPPLPAECLDIDGDWNTLPVI
FEDRYVDCPAT-GH--NL-------SVYP--NFDVPVT--SPTIMNLK------------
------------E-K----ED--NCMVNGNLSF--REDLV-LST--LKP--SQMD-----
---------------SDEEVIRCPELAENVAT-------QNHMDVCS---E---------
S-QVYITIGEFQNKAG-VP-------EDEC------------------------------
--------------WTGQTSEAGTHPMAD--------VDTSRRS---PGP----------
---------EDGQAPVLTYIDVKSSNKNPSRA-----EPLVAFNAQHENRSSRDKYGLDR
TGLSKVVVG--------GSHQNAISSDKTTLH--ELS---T--LGKGIDQEGK-------
----MVLLSLKLTP---SEPCDP-LNSTLREPLDIRSSLKDSHTEEQEELSVLSGVIKRS
SSIISDSGIESEPSSVAWSEARSRALELPSDREVLHPFVRRHALHRNSLEGGHTESNTSL
PSGIQASLTSISSLPFEEDEREVA-LTKLTKSVSAPHISSPEEAAEDADTKQQGGGFAEP
SDMYSKS------QGSPGPCSQ-LCGDSG-----------------TQDA-GVDHPLVE-
-IALDAD----NQQGPGYIDIPKGKGKQFDAQGHC-----------------LPDGRTEN
T--PGVET----KGLNL-KIPRVIALENPRTRSLH---RALVETPKGIPKDL--NVGQPA
LSNSG--ISEVEGLSQ--HQV--PE---L-SYTSAA-----DAINMNSTGQQSQSGSPCI
VDDTAFN-R---------GANAFPEAKHKAG----TVCPT------VTHSVHSQVLKNQE
LKAGTSIMGSHLTSAETFTLDSLKAVEVVNLSVSCTATCLPFSSVPKETPARAGFSSKQT
LFPITHQPLGSFGVVSTHSSTLDEEVSERMFS----FYQAKEKFKKELKIEGFLYSDLTV
LASDIPYFPPEEEEENLE

PF05057 // ENSGT00390000007885_1_Domain_2 (1459, 1657)

DGIHLVVCVHGLDGNSADLRLVKTFIELGLPGGKLDFLMSEK
NQ-MDTFADFDTMTDRLLDEIIQHIQLYNLS-ISRI--SFIGHSLGNII-IRSVLTRPRF
RYYLNKLHTFLSLSGPHLGTLYNNSTLVSTGLWLMQKLKKSGSLLQLTFRDNADLRKCFL
YQLSQKTGLQYFKNVVLVASPQDRYVPFHSARIEMCKTALKDRHTGPVYAEMINNLLGPL
VEAKDCTLIRHNVFHALPNTANTLIGRAAHIAVLDSELFLEKFF---LVA-GLNYFK---
---------

MSEIQGTVEFSVELHKFYNVDLFQRGYYQIRVTLKVSSRIPHRLSASIAGQTESS----S
LHSACVHDSTVHSRVFQILYRNEEVPINDAVVFRVHLLLGGERMEDALSEVDFQ

PF12394 // ENSGT00390000007885_1_Domain_0 (115, 177)

LKVDLH
FTDSEQQ-LRDVAGAPMVSSRTLGLHFHPRNGLHHQVPVMFDYFHLSVISVTVHAALVAL
QQPLISFTRPGRGSWLGKGGPDTGQEQSIISLENLVFGAGYCKPTSS-EGSFYITSENCM
QHAHKWHRDLCLLLLHAYRGLRLHFLVIMRDIPELPHTEL-EALAVEETLSQLCSELQML
NNPEKIAE--QISKDLAWLTS-HMMTLWTQFLDTVTLHSQVTTYLTQEHHTLRVRRFSEA
F--FYMEHQKLAVLTFQENLIQTHSQLSLDIRNSEYLTSMPPLPAECLDIDGDWNTLPVI
FEDRYVDCPAT-GH--NL-------SVYP--NFDVPVT--SPTIMNLK------------
------------D-K----ED--NCMVNSNLSF--REDLV-LST--IKP--SQMD-----
---------------SDEEVIRCPEPGENVAT-------QNHMDMCS---E---------
S-QVYISIGEFQNKAG-VP-------EDEC------------------------------
--------------WTGQTSDAGTYPVAD--------VDTSRRS---PGP----------
---------EDGQAPVLTYIDVKSSNKNPSRA-----EPLVAFNAQHESRSSRDKYGLDR
TGLSKVVVG--------GSHQNAISSDKTTLH--ELS---T--LGKGIDQEGK-------
----MVLLSLKLTP---SEPCDP-LSSTLREPLDIRSSLKDSHTEEQEELSVLSGVIKRS
SSIISDSGIESEPSSVAWSEARSRALELPSDREVLHPFVRRHALHRNSLEGGHTESNTSL
PSGIQASLTSISSLPFEEDEREVA-LTKLTKSVSAPHISSPEEAAEDADTKQQDGGFAEP
SDMHSKS------QGSPGSCSQ-LCGDSG------------------TDA-GADHPLVE-
-IVLDAD----NQQGPGYIDIPKGKGKQFDAQGHC-----------------LPDGRTEN
T--PGVET----KGLNL-KIPRVIALENPRTRSLH---RALEETPKGMPKDL--NVGQQA
LSNSG--ISEVEGLSQ--HQV--PE---L-SCTSAA-----DAINRNSTGQQSQSGSPCI
MDDTAFN-R---------GVNAFPEAKHKAG----TVCPT------VTHSVHSQVLKNQE
LKAGTSIMGSHLTSAETFTLDSLKAVEVVNLSVSCTATCLPFSSVPKETPARAGFSSKQT
LFPITHQPLGSFGVVSTHSSTLDEEVSERMFS----FYQAKEKFKKELKIEGFLYSDLTV
LASDIPYFPPEEEEENLE

PF05057 // ENSGT00390000007885_1_Domain_2 (1459, 1657)

DGIHLVVCVHGLDGNSADLRLVKTFIELGLPGGKLDFLMSEK
NQ-MDTFADFDTMTDRLLDEIIQHIQLYNLS-ISRI--SFIGHSLGNII-IRSVLTRPRF
RYYLNKLHTFLSLSGPHLGTLYNNSTLVSTGLWLMQKLKKSGSLLQLTFRDNADLRKCFL
YQLSQKTGLQYFKNVVLVASPQDRYVPFHSARIEMCKTALKDRHTGPVYAEMINNLLGPL
VEAKDCTLIRHNVFHALPNTANTLIGRAAHIAVLDSELFLEKFF---LVA-GLNYFK---
---------

MSEVQGTVEFSVELHKFYNVDLFQRGYYQIRVTLKVSSRIPHRLSASIVGQTDSS----S
PHSACVHDSTMRSRVFQILYRNEEVPINDAVIFRAHLLLDGERVEEAVSEVDFQ

PF12394 // ENSGT00390000007885_1_Domain_0 (115, 178)

LKVDLH
FTDSEQQ-LRDMAGVPVISSRVLGLHFHPRRGLHHQVPVMFDYFHLSVISVTIHAAL

ENSGT00390000007885_1_Linker_0_1 (178, 323)

VAL
QQPLISFTRPGRGSWLGKGGPDTGPEQSSLSLENLVFGAGYCKPTSS-EGSFYVPSENCM
QHAYKWHRELCFLLLHAYRGLRAYFLTILRDIPELPRVEL-ESLAVEETLSQLCSELQML
NNPEKIAE--QISKDLAWLAS-

PF12394 // ENSGT00390000007885_1_Domain_1 (323, 381)

HLMALWTQFLDTVTLHSQVTTYLTQEHHTLRVRRFSEA
F--FYMEHQKLAVLTFQENL

ENSGT00390000007885_1_Linker_1_2 (381, 1464)

IQTHSQLSLDIRNSEYLTTMPPLPAECLDIDGDWNTLPVI
FEDRYVDCPATVGC--NL-------NIYP--NFDVPAT--SPAIINLN------------
------------N-R----EE--NLVVNRKSPL--RENLV-LAS--MKP--PPMD-----
---------------SDEEVLRCPGPSKNGTT-------PSHMDVCS---E---------
S-QVYLTVGEFQSKAG-VP-------EVDH------------------------------
--------------QTGPRSDVGGHPLAD--------EDLPRRS---PGP----------
---------EDGQAPALTYIDVKSSNKNPFRA-----EPTVLTGAQHESGCSRDKHGLGR
TERTKGIAG--------GGHHSAVSSEKTTLH--ELS---S--LGKGVDQGSK-------
----VVLLSLKVTP---SEPCEP-LNSSLRDPLDIKGSPKDPQAEEKEEVCVLSGVIKRS
ASIISDSGIESEPSSVAWSEARSRTLELPSDRDFLHQLVRRHALHRNSLEGGHTESNTSL
PSGIQASLTSISSLPFEEEERELA-LTKLTKSVSAPQISSPEESAEDADSTRHRGGPAET
SAVPTKS------TNPSGHCLR-PSDGPA-----------------IQEA-GVDHALVE-
-EVSAAD----NLQGPGYIDIPKGQEDRFDPQGPC-----------------CLDGRTDN
P--PGVET----KGLGL-KIPRLLGLASPGHRALP---RELVETPKGMPGDS--NAGTGA
PLDSSIGMLDVESFTH--PKV--PE---V-SCAPSI-----D---VDSAGEQS--SSLGV
MEDTAPS-R---------GADTFPEDDREAG----M-GSA------VTQSIPSPVTGNQE
PRPGTSIMLSHVTSAETFSLDSLKAVEVVNLSVSCTATCLPFSSVPKETPARAGFSSKQT
LFPITHQPLGSFGVVPNHSRKLEEEVSERMFS----FYQAKEKFKKELKIDGFLYSDLSV
LASDIPYFPPEEEEENLEDGIHL

PF07819 // ENSGT00390000007885_1_Domain_2 (1464, 1583)

VVCVHGLDGNSADLRLVKTFIELGLPGGKLDFLMSEK
NQ-MDTFADFDTMTDRLLDEIIQHIQLYNLS-ISRI--SFIGHSLGNII-IRSVLTRPRF
RYYLNKLHTFLSLSGPHLGTLYNNSALVSTGLWLMQKLKKSGSLLQLTFRDNADLRKCFL
YQLSQKTGLQYFKNVVLVASPQDRYVPFHSARIEMCKTALRDRHTGPVYAEMINNLLRPL
VDAKDCTLIRHNVFHALPNTANTLIGRAAHIAVLDSELFLEKFF---LVA-GLNYFK---
---------

------------------------------------------------------------
-------------------------------------------VEEALSEIDFQLKVDLH
FTDSEQQ-LRDVAGAPMISSRTLGLHFHPRRGLHHQVPVMFDYFHLSVISVTIHAALVAL
QQPLIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XGSFYVPSENCM
QRAYKWHRELCFLLLHAYRGLRAYFLVIMRDIPELPHTEL-ESLAVEETLAQLCSDLQIL
SNPEKIAE--HISKDLTWLTS-HLMALWTQFLDTVTLHSQVTTYLTQEHHSLRVRRFSEA
F--FYMEHQKLAVLTFQENLIQSHSQLSLDVRNSEYLTTMPPLPAECLEIDGDWNTLPVI
FEDRYVDCPAT-GH--NL-------TFYP--NFAVSEA--GTTITNLK------------
------------V-Q----EE--GHIINKKPSI--REDLV-LSN--IKQ--PQMD-----
---------------SG-EIIRCSEPDETATT-------PNHTGELS---E---------
S-QVYLTIGEFQNKTD-FP-------KDES------------------------------
--------------QSDQRFEVGAHSVAE--------VDWPRRS---PGP----------
---------EDAQASTLTYIDVKPSNKNPCRN-----EPTVVISTQYESGCSAANSDSDG
TVISQEEVG--------RGHQNAISSEKSMPH--ELR---V--TGKGADQEGK-------
----LVLLSLKLMP---SEPCVT-VNSTLRDPLDTRASPKDPHK-EQEDMSLLSGVIKRS
SSLISDSGIESEPSSVAWSEARSRALEPPNDQEVLHQLVRRHALHRNSLEGGHTESNTSL
PSGIQASLTSISSLPFEEEEKELA-LTKLTKSLSAPQISSPEESSEDTEAVLQDEIVTEA
SVEHIKS------KDSPEHCPQ-LCKVSR-----------------IQDN-GAEDSFVE-
-VILDAD----NQQDPGYIDIPQSKESQFDLQASC-----------------CLDDRTEN
S--PGVEA----KGHNF-EIPHNIAIGSPMNRSVT---RELTEIPKDMAKDL--NSGNSS
QSQST--IIGNEATNH--HQV--PE---L-NCMSAA-----ESVVKN--------GSAGT
VDATPLS-R---------RADTFMELGLKAG----TVCPT------VTPSLPSQVLENQE
PRACNSITVPQQNSSETFTLDSLKTVEVINLSVYCTATCLPFSSVPKETPARAGFSSKQT
PFPITHQPLGSFGVVSTHSSSLEEEVSERMFS----FYQAKEKFKKELKIDGFLYSDLSV
LASDVPYFPPEEEEEN

PF07819 // ENSGT00390000007885_1_Domain_2 (1457, 1700)

LEDGIHLVVCVHGLDGNSADLRLVKTFIELGLPGGKLDFLMSEK
NQ-MDTFADFDTMTDRLLDEIIQHIQLYNLS-ISRI--SFIGHSLGNII-IRSVLTRPRF
RYYLNKLHTFLSLSGPHLGTLYNNSTLVSTGLWLMQKLKKSGSLLQLTFRDNADLRKCFL
YQLSQKTGLQYFKNVVLVASPQDRYVPFHSARIEMCKTALKDRHTGPVYAEMIDNLLRPL
VEAKDCTLIRHNVFHALPNTANTLIGRAAHIAVLDSELFLEKFF---LVA-GLNYFK---
---------

MSEVQGTVEFSVELHKFYNVDLFQRGYYQIRVTLKVSSRIPHRLSASIVGQTESS----S
LRAACVHEGIMHSRVFQILYRNEEVLINDAAIFQAHLLLDGERVEDALSEVDFQ

PF12394 // ENSGT00390000007885_1_Domain_0 (115, 178)

LKVDLH
FTDSEQQ-LRDVAGPPMISSRTLGLHFHPRNGLHHQVPVMFDYFHLSVISVTIHAAL

ENSGT00390000007885_1_Linker_0_1 (178, 324)

VSL
RQPLISFTRPGRGSWLGKGGPDMGQEQSIISLENLVFGAGYCKPTSS-EGSFYAPSEHCM
QHAYKWHRDLCLLLLQAYQGLRLYFLLIMRDIPELPHTEL-EALAVEETLSQLCSELQML
NNPEKMAE--QISKDLAWLAG-H

PF12394 // ENSGT00390000007885_1_Domain_1 (324, 381)

LMALWTHFLDTVTLHAHVTTYLTQEHHTLRVRRFSEA
F--FYMEHQKVAVLTFQENL

ENSGT00390000007885_1_Linker_1_2 (381, 1459)

IQSHSQLSLDVRNSEYLASMPPLPAECLDIDGDWSTLPVI
FEDRYVDCPGK-GN--NL-------SLCP--KFDVSVT--SPTVTNLK------------
------------KKK----EE--NHIVNRKLSV--TDELV-SST--VKP--PQVD-----
---------------LDGDVIRGPKPDKNITT-------RNPADVCS---E---------
S-QVYLTVGEFQDKAG-AQ-------KDKS------------------------------
--------------GTGQRSDVGTHLLAK--------ADLSQRS---PDP----------
---------EDGQAPALTYIDVNSSNKTPSKA-----ESTVVVSAQHESRSSRHKCGSDR
NGLSKVVTV--------ESHQNAISLDKIALH-GELS---T--VGKGGEQESK-------
----VLLLRLKIIP---SEPCDPLSSTPKEPLVDARSSLKDPQQEEQEELSVLSGVIKRS
SSIISDSGIESEPSSFAWSEARSRALELPSDREVLQPSARRHGLHRSSLEGGHTESNVSL
PSGIQASLTSISSLPFEEEERELA-LTKLTKSVSAPQISSPEEAANETDPEQQGRDFGET
PDMYLQG------KDSPGHCAH-LCHGSR-----------------VQDA-RTE------
---SDGD----HLHGPGYMDIPKGKASQSDPRGDC-----------------HLESRTEN
T--GSLET----KVLNL-KIPCVIALESPGTRSFQ---RALVETPKGIARDL--DVGKQA
LSSSG--VSEVEGISP--HKV--PE---S-NRTSEA-----DVISQSSPGKKR--SSPRT
TDDRGGD-R---------GVTASSEGRHKAG----TVCPT------VTHSIHSKVSRNQE
PQANTSVGVSPVTSTESFSLEGLKAVEVVNLSVSCTATCLPFSSVTKEPPVRTGFSSKQT
LFPITHQPLGSFGVVSAHPSELEEEVSERMFS----FYQAKEKFKKELKIEGFLYSDVSV
LASDMPYFPPEEEEETLE

PF05057 // ENSGT00390000007885_1_Domain_2 (1459, 1657)

DGIHLVVCVHGLDGNSADLRLVKTFIELGLPGGKLDFLMSEK
NQ-PDTFADFDTMTDRLLDEIIQHIQLYNLS-ISRI--SFIGHSLGNII-IRSVLTRPRF
RYYLNKLHTFLSLSGPHLGTLYSNSALVSTGLWLMQKLKKSGSLLQLTFRDNADLRKCFL
YQLSQKTGLQYFKNVVLVASPQDRYVPFHSARIEMCKTALKDRHTGPVYAEMINNLLGPL
VEAKDCTLVRHNVFHALPNTANTLIGRAAHIAVLDSELFLEKFF---LVA-GLNYFK---
---------

MSEVQGTVEFSVELHKFYNVDLFQRGYYQIRVTLKVSSRIPHRLSASIAGQTESN----S
VNSACVYESTVHSRVFQILYRNEEVPINDAVLFRAHLLLDGERVEDALSEVEFQ

PF12394 // ENSGT00390000007885_1_Domain_0 (115, 177)

LKVDLH
FTDSEQQ-LRDVAGAPMISSRTLGLHFHPRRGLHHQVPVMFDYFHLSVISVTVHAALVAL
QQPLISFTRPGRGSWLGKGGPDAGPEPSVISLENLVFGAGYCKPTSS-EGSFYVPSENCM
QHARKWHRDLCFLLLHAYRGLRLYFHVIMRDVPELPHAEL-KALAVEETLSRLCSELQVI
RALTLGGR--KGSL---QAGS-RLLLVS------TT----------EHLRHQRCRDFSHA
N--HSSRSDDQG------HLV------------------------------------P--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------

MSEVQGTVEFSVELHKFYNVDLFQRGYYQIRVTLKVSSRIPHRLSASIVGQSESS----S
LHSACVHESAVHSRVFQILYRNEEVSINDAMLFRVHLLLDGERVEDALSEVEFQ

PF12394 // ENSGT00390000007885_1_Domain_0 (115, 177)

LKVDLH
FTDSEQQ-LRDVTGTPMISSRTLGLHFHPRRGLHHQVPVMFDYFHLSVISVAIHAALVAL
QQPLISFTRPGRGSWLGKGGPDTGPEQPTISLENLVFGAGYCKPTSS-EGSFYVPSENCI
QHAHKWHRDLCLLLLHAYQGLRLYFLVIMRDIPELPTMEL-EALAVEETLSQLCSELQML
NNPEKIAE--QISKDLAWLAS-HLMALWTQFLDTVTLHSQVTTYLTQEHHTLRVRRFSEA
F--FYMEHQKLAVLTFQENLIQTHSQLSLDIRNSEYLTSMPPLPAECLDIDGDWNTLPVI
FEDRYVDCPVS-GH--NL-------SVYP--NFDVPVT--SPAIMNLK------------
------------G-K----EK--N-LINQNSSS--RKDVP-LST--TEA--PQLG-----
---------------SEEDVTRRPEVQENVSP-------WNPIDVCS---E---------
S-QVYLTIGEFQNRAG-IP-------EDEC------------------------------
--------------WTGPRPDAVKDSLTD--------TDICSRS---PGP----------
---------DEGQTPALTYIDVQSSNKYCPRA-----ELVQGINVQHEHRSSRESYGIVK
TVPSKVVAG--------TSQNNSISLNQTAAL--ELR---T--LGRGVNQDGK-------
----PVLLSLKLTP---AEPCDP-PSTALREALDTKPSQP-DHAEEPEDLSVLSGVIKRS
ASIISDSGIESEPSSVAWSEARSRALELPSDRDVLHQVVRRHAHHRNSLEGGHTESNTSL
PSGIQASLSSISSLPFEEEERELA-LNKLTKSVSAPQISSPEDSAEGADTIKNTAGFSED
LDLSSKE------NSSPRHTSL-LYGGSR-----------------VQDV-RAGHSLVD-
-IALDSD----RPQGPGYMDIPNDKGNHPELQEPC-----------------CLDGMAET
P--LHVET----KGLNL-KIPCTIVLENSKSRSFH---RAAVETAKGKPEEL--SMSKHV
LSNNS--ISEVRAASH--HRV--PE---I-SCSPAV-----EAVNLNSIGVQNSS--LSV
NDTMTLN-R---------RHNASLEAKHEAG----TVCPT------VTHTIASQASRNQE
LKTGTSISGSHLNSTEAFTLDSLKAVEVVNLSVSCTATCLPFSSVPKETPARAGLSSKQN
PAPITHQPLGSFGVVSTYSSKLEEEVSERMFS----FYQAKEKFKKELKIEGFLYSDLSV
LASDIPYFPPEEEEENLE

PF05057 // ENSGT00390000007885_1_Domain_2 (1459, 1657)

DGIHLVVCVHGLDGNSADLRLVKTFIELGLPGGKLDFLMSEK
NQ-TDTFADFDTMTDRLLDEIIQHIQLYNLS-ISRI--SFIGHSLGNII-IRSVLTRPRF
RYYLNKLHTFLSLSGPHLGTLYNNSTLVSTGLWLMQKLKKSGSLLQLTFRDNADLRKCFL
YQLSQKTGLQYFKNVVLVASPQDRYVPFHSARIEMCKTALKDRHTGPVYAEMINNLLGPL
VEAKDCTLIRHNVFHALPNTANTLIGRAAHIAVLDSELFLEKFF---LVA-GLNYFK---
---------

MSEVQGTVEFSVELHKFYNVDLFQRGYYQIRVTLKVSSRIPHRLSASIVGQSESS----S
LHSACVHESAVHSRIFQILYRNEEVPVNDAMLFRAHLLLDGERVEDALSEVEFQ

PF12394 // ENSGT00390000007885_1_Domain_0 (115, 177)

LKVDLH
FTDSEQQ-LRDVTGTPMISSRTLGLHFHPRRGLHHQVPVMFDYFHLSVISVTIHAALVAL
QQPLISFTRPGRGTWLGKGGLDAGPEQPTISLENLVFGAGYCKPTSS-EGSFYVPSENCI
QHAHKRHRDLCLMLLHAYQGLRLYFLVIMRDIPELPTMEL-EALAVEETLSQLCSELQVI
TVLTLC--------PNLWKCL---------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------

MSEVQGTVEFSVELHKFYNVDLFQRGYYQIRVTLKVSSRIPHRLSASIVGQSESS----S
LHSACVHESAVHSRVFQILYRNEEVSINDAMLFRVHLLLDGERVEDALSEVEFQ

PF12394 // ENSGT00390000007885_1_Domain_0 (115, 177)

LKVDLH
FTDSEQQ-LRDVTGTPMISSRTLGLHFHPRRGLHHQVPVMFDYFHLSVISVAIHAALVAL
QQPLISFTRPGRGSWLGKGGPDTGSEQPTISLENLVFGAGYCKPTSS-EGSFYVPSENCI
QHAHKWHQDLCLLLLHAYQGLRLYFLVIMRDIPELPTLEL-EALAVEETLSQLCSELQML
NNPEKIAE--QISKDLAWLAS-HLMALWTQFLDTVTLHSQVTTYLTQEHHTLRVRRFSEA
F--FYMEHQKLAVLTFQENLIQTHSQLSLDIRNSEYLTSMPPLPAECLDIDGDWNTLPVI
FEDRYVDCPVS-GH--NL-------SVYP--NFDAPVT--SPAIMNLK------------
------------G-K----EK--N-LINQKSSS--RKDIP-LST--TEA--PQLG-----
---------------SDEDVIRCPEMQENISP-------RNPMDVCS---E---------
S-QVYLTIGEFQNRAG-IP-------EDEC------------------------------
--------------WTGPRPDAVKDSLTD--------TDICSRS---PGP----------
---------EEGQTPALTYIDVQSSNKYYLRS-----ELVQGINVQHEHRSSRDSYGIVK
TMPSKVVAG--------TSQNNSISLNQTAAL--ELR---T--LGKGVDQEGK-------
----PVLLSLKLTP---AEPGDSPPSTALREALDTKLSLP-DHAEEPEDLSVLSGVIKRS
ASLISDSGIESEPSSVAWSEARSRALELPSDRDVLHQVIRRHAHHRNSLEGGHTESNTSL
PSGIQASLSSISSLPFEDEERELA-LNKLTKSVSAPQISSPEDTAEGTDTIKNTAGFSED
LDLSSKD------NSSPRHTSP-SYGGSK-----------------VQDV-RAGHSLAD-
-IALDSD----RPQSPGYMDIPNGQENHPDLQEPC-----------------CQDGMAET
T--LHAET----KGLNL-KIPCTIVLENSKSRSFH---RAAVETAKGKPEEL--SMSKHM
LSNNS--ISEVRAASH--HRV--PE---I-SCSPAV-----EAVNLNSTGIQKSS--LSV
NDTRTLN-R---------RHNASLEATHEAG----TVCPT------VTHTIASQSSRNQE
LKAGTSIPGSHLNSTEAFTLDNLKAVEVVNLSVSCTATCLPFSSVPKETPARAGLSSKQN
PAPITHQPLGSFGIVPTYSSKLEEDISERMLS----FYQAKEKFKKELKIEGFLYSDLSV
LASDIPYFPPEEEEENLE

PF05057 // ENSGT00390000007885_1_Domain_2 (1459, 1657)

DGIHLVVCVHGLDGNSADLRLVKTFIELGLPGGKLDFLMSEK
NQ-TDTFADFDTMTDRLLDEIIQHIQLYNLS-ISRI--SFIGHSLGNII-IRSVLTRPRF
RYYLNKLHTFLSLSGPHLGTLYNNSTLVSTGLWLMQKLKKSGSLLQLTFRDNADLRKCFL
YQLSQKTGLQYFKNVVLVASPQDRYVPFHSARIEMCKTALKDRHTGPVYAEMINNLLGPL
VEAKDCTLIRHNVFHALPNTANTLIGRAAHIAVLDSELFLEKFF---LVA-GLNYFK---
---------

MSEVQGTVEFSVELHKFYNVDLFQRGYYQIRVTLKVSSRIPHRLSASIVGQSESN----S
VHSACVHENAVHSRVFQILYRNEEAPINDAMVFRAHLLLDGERVEDALSEVEFQ

PF12394 // ENSGT00390000007885_1_Domain_0 (115, 177)

LKVDLH
FTDSEQL-LRDRTGTPMISSRTLGLHFHPRSGLHHQVPVMFHYCHLSVISVTVHAALVAL
QQPLISFTRPGRGSWLGKGGPDMGPEQPLISLENLVFGAGYCKPTSS-EGSFYVPSENCI
QHAHKWHRDVCLLLLQAYRGLRLYFLVIMRDIPELPHMDL-EALAVEETLSQLCSELQVI
TVLTLSLKDGNYSTGLSQFCLPHSMP-----------VTEVTSFPKEKE-----------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------

MSEVQGTVEFSVELHKFYNVDLFQRGYYQIRVTLKVSSRIPHRLSASIVGQSESS----N
LHSACVHESAVHSRVFQILYRNEEVPINDVMLFRAHLLLDGERVEDALSEVEFQ

PF12394 // ENSGT00390000007885_1_Domain_0 (115, 177)

LKVDLH
FTDSEQQ-LRDVTGTPMISSRTLGLHFHPRRGLHHQVPVMFDYFHLSVISVTIHAALVAL
QQPLISFARPGRGSWLGKGGPDTGPEQPIISLENLVFGAGYCKPTSS-EGSFYVPSENCI
QHAHKWHRDLCLMLLHAYQGLRLYFLVIMRDIPELPTMEL-EALDVEETLSQLCSELQML
NNPEKIAE--QISKDLTWLAS-HLMALWTQFLDTVTLHSQVTIYLTQEHHTLRVRRFSEA
F--FYMEHQKLAVLTFQENLIQTHSQLSLDIRNSEYLTSMPPLPAECLDIDGDWNTLPVI
FEDRYVDCPVS-GH--NL-------SVDP--NFDVPVT--STATMNLK------------
------------E-K----EK--N-VINEKSSL--GKDLP-LST--TNT--PQLG-----
---------------SDENVISCSETEENVST-------QNPVDVCS---E---------
S-QVYLTIGEFQNKAV-MP-------KDEC------------------------------
--------------WTGPRPVRDS----D--------VD-MHRS---PCP----------
---------EDGKTPALTYIDVKSSNKNHPRA-----EPIQGLNVHHEHIRSRESYDLVK
TLPNKIVAG--------ISQNNAINLNQTAAL--DFR---T--LGRGADQEGK-------
----PVLLSLKLTP---AEPFDP-LNTALREPLNNMSSLQD-STEEQEDLSVLSGIIKRS
ASIISDSGIDSEPSSVALSEARSRVLDLPSDREVLHKVVQRYAHHRNSLEGGHTESNTSL
PSGIQASLTSISSLPFEDEERELA-LTKLTKSVSAPQISSPEDTTEDADTMKNTGGFSED
--ISSKD------NNSPRHSFH-SYGGSR-----------------VQDV-RAGHSLAD-
-IAIDSD----RPQGPGYIDIPKGKVNQSDLQGPC-----------------SLGGMAEN
P--PSVET----KGLNL-KIPCTIVLENSRTRSVH---RGAVGTTKGKPKES--SGGKHI
LPNNS--ILEARAVSH--HRV--PE---I-SSSSAV-----EAVNLISTGVQN--GSSSV
NDTMTLN-R---------RHNASLEVSQEAG----TVCPS------VTHSIASQMSRNQE
MKTGTSISGSHLNSAEAFTLDSLKAVEVVNLSVSCTATCLPFSSVPKEPPARAGLSSKQS
LSPITHQPLGSFGVVSTHSRKLE-EVSERMLS----FYQAKEKLKKELKIEGFLYSDLSE
LASDIPYFPPEEEEENLE

PF05057 // ENSGT00390000007885_1_Domain_2 (1459, 1657)

DGIHLVVCVHGLDGNSADLRLVKTFIELGLPGGKLDFLMSEK
NQ-MDTFADFDTMTDRLLDEIIQHIQLYNLS-ISRI--SFIGHSLGNII-IRSVLTRPRF
RYYLNKLHTFLSLSGPHLGTLYNNSTLVSTGLWLMQKLKKSGSLLQLTFRDNADLRKCFL
YQLSQKTGLQYFKNVVLVASPQDRYVPFHSARIEMCKTALRDRHTGPVYAEMINNLLGPL
VEAKGCTLIRHNVFHALPNTANTLIGRAAHIAVLDSELFLEKFF---LVA-GLNYFK---
---------

----------------------------------------------------EST----S
LHSACIHESTMHSRVFQILYRNEEVPINDAVIFRAHLLLDGERVEDALNEVDFQ

PF12394 // ENSGT00390000007885_1_Domain_0 (115, 178)

LKVDLH
FTDSEQQ-LRDVAGAPMISSRTLGLHFHPRRGLHHQVPVMFDYFHLSVISVTIHAAL

ENSGT00390000007885_1_Linker_0_1 (178, 323)

VAL
QQPLISFTRPGRGSWLGKAGPDAGPEQPSISLENLVFGAGYCKPTSS-EGSFYVPSENCM
QHAYKWHRDLCHLLLHAFRGLRAYFLSIMRDIPELPHMEL-EALAVEETLSQLCSELQML
NNPEKIAE--QISKDLAWLAS-

PF12394 // ENSGT00390000007885_1_Domain_1 (323, 381)

HLMALWTQFLDTVTLHSQVTTYLTQEHHTLRVRRFSEA
F--FYMEHPKLAVLTFQENL

ENSGT00390000007885_1_Linker_1_2 (381, 1459)

TQTHSQLSLDVRNSEYLTSMPPLPAECLDIDGDWNTLPVI
FEDRYVDCPAM-GH--DL-------SVYP--NFDVPVI--SPTRMTLQD-----------
------------------SEE--NHSGNCKSSF--REDLV-LVS--RKP--LLLD-----
---------------SGEQVMRGPDPGENLMT-------PNHANLCS---A---------
S-QVYLTVGEFQNKAG-LP-------EEEC------------------------------
--------------WSD----GSAHPLAD--------GDMLRRS---LGP----------
---------EDGQGPAVTYIDVESSNKSPHRT-----EPTTGICAQRGSEASGENNGLDQ
TVLSKVAAG--------RRHQSAVSSDKTALHE--SS---T--LGKGADRDGR-------
----TVLLSLKPIP---SEPCDP-LGSTLRDPLDIRSSPKDPCTEEQEEGSVVSRAIKRS
SSIISDSGIESEPSSVAWSEARSRALELPSDREVLHQLVRRHAFHRNSLEGGHTESNTSL
PSGIQASLTSISSLPFEEEERELA-LTKLTKSVSAPQISSPEEAAEGLDTRQQGGGLEAS
DI-H-KS------TDSPGNYSQ-LCGDSI-----------------IQDA-RADHLHAE-
-IILDAG----DHQGPSYIDIPKGNESQFDPQRHC-----------------SLDGRTEN
P--PGVEA----KGLNF-TIPRLIALEPSGNRLVH---RALLETPKGVPKDL--NAGKGA
LSNSS--ISDVEDLSH--HQV--PE---L-HCPPVA-----HAIDLGPTEEQS--KLPCV
TDAAVLN-R---------GADASQELEPRAR----TGCPT------VTHSIHSQVSGNQE
PKTGTSIMVSHLSPPETFALDSRKAVEVVNLSVSCTATCLPFSSVLKETPARAGFSSKQN
PFPITHQPLGSFGVVSTQTSKLEEEVSERMFS----FYQAKEKFKKELKIEGFLYSDSAV
LASDMPYFPPEEEEENLE

PF05057 // ENSGT00390000007885_1_Domain_2 (1459, 1657)

DGIHLVVCVHGLDGNSADLRLVKTFIELGLPGGKLDFLMSEK
NQ-MDTFADFDTMTDRLLDEIIQHIQLYNLS-ISRIRRSFIGHSLGNII-IRSVLTRPRF
RYYLNKLHTFLSLSGPHLGTLYNNSTLVSTGLWLMQKLKKSGSLLQLTFRDNADLRKCFL
YQLSQKTGLQYFKNVVLVASPQDRYVPFHSARIEMCKTALKDRYAGPVYAEMINNLLSPL
AEAKDCTLIRHNVFHALPNTANTLIGRAAHIAVLDSELFLEKFF---LVA-GLNYFK---
---------

MSEVQGTVEFSVELHKFYNVDLFQRGYYQIRVTLKVSSRIPHRLSASIVGQSESS----N
LHSACVHESAVHSRVFQILYRNEEVPINDVMLFRAHLLLDGERVEDALSEVEFQ

PF12394 // ENSGT00390000007885_1_Domain_0 (115, 177)

LKVDLH
FTDSEQQ-LRDVTGTPMISSRTLGLHFHPRRGLHHQVPVMFDYFHLSVISVTIHAALVAL
QQPLISFARPGRGSWLGKGGPDTGPEQPIISLENLVFGAGYCKPTSS-EGSFYVPSENCI
QHAHKWHRDLCLMLLHAYQGLRLYFLVIMRDIPELPTMEL-EALDVEETLSQLCSELQML
NNPEKIAE--QISKDLTWLAS-HLMALWTQFLDTVTLHSQVTIYLTQEHHTLRVRRFSEA
F--FYMEHQKLAVLTFQENLIQTHSQLSLDIRNSEYLTSMPPLPAECLDIDGDWNTLPVI
FEDRYVDCPVS-GH--NL-------SVDP--NFDVPVT--STATMNLK------------
------------E-K----EK--N-VINEKSSL--GKDLP-LST--TNT--PQLG-----
---------------SDENVISCSETEENVST-------QNPVDVCS---E---------
S-QVYLTIGEFQNKAV-MP-------KDEC------------------------------
--------------WTGPRPVRDS----D--------VD-MHRS---PCP----------
---------EDGKTPALTYIDVKSSNKNHPRA-----EPIQGLNVHHEHIRSRESYDLVK
TLPNKIVAG--------ISQNNAINLNQTAAL--DFR---T--LGRGADQEGK-------
----PVLLSLKLTP---AEPFDP-LNTALREPLNNMSSLQD-STEEQEDLSVLSGIIKRS
ASIISDSGIDSEPSSVALSEARSRVLDLPSDREVLHKVVQRYAHHRNSLEGGHTESNTSL
PSGIQASLTSISSLPFEDEERELA-LTKLTKSVSAPQISSPEDTTEDADTMKNTGGFSED
--ISSKD------NNSPRHSFH-SYGGSR-----------------VQDV-RAGHSLAD-
-IAIDSD----RPQGPGYIDIPKGKVNQSDLQGPC-----------------SLGGMAEN
P--PSVET----KGLNL-KIPCTIVLENSRTRSVH---RGAVGTTKGKPKES--SGGKHI
LPNNS--ILEARAVSH--HRV--PE---I-SSSSAV-----EAVNLISTGVQN--GSSSV
NDTMTLN-R---------RHNASLEVSQEAG----TVCPS------VTHSIASQMSRNQE
MKTGTSISGSHLNSAEAFTLDSLKAVEVVNLSVSCTATCLPFSSVPKEPPARAGLSSKQS
LSPITHQPLGSFGVVSTHSRKLE-EVSERMLS----FYQAKEKLKKELKIEGFLYSDLSE
LASDIPYFPPEEEEENLE

PF05057 // ENSGT00390000007885_1_Domain_2 (1459, 1657)

DGIHLVVCVHGLDGNSADLRLVKTFIELGLPGGKLDFLMSEK
NQ-MDTFADFDTMTDRLLDEIIQHIQLYNLS-ISRI--SFIGHSLGNII-IRSVLTRPRF
RYYLNKLHTFLSLSGPHLGTLYNNSTLVSTGLWLMQKLKKSGSLLQLTFRDNADLRKCFL
YQLSQKTGLQYFKNVVLVASPQDRYVPFHSARIEMCKTALRDRHTGPVYAEMINNLLGPL
VEAKGCTLIRHNVFHALPNTANTLIGRAAHIAVLDSELFLEKFF---LVA-GLNYFK---
---------

MSEVQGTVEFSVELHKFHNVDLFQRGHYQVRVTLKVPSRIPHRLSVKIGGQTEVS----N
LGSASVQDNTGNSRIFQILYRNEEIVINELMTFRVHLLLDGERVENALSEVDFQ

PF12394 // ENSGT00390000007885_1_Domain_0 (115, 178)

LKLDLH
FTESEQQ-ARDLAAMPTISSRTLDLHFQPRKGLHHYIPVMFDYFHLSVISMTIHASL

ENSGT00390000007885_1_Linker_0_1 (178, 327)

VAL
QQPLISFTRPGKGSWLGKGSAESGSEQSSMSLESLVFGAGYCKPSFS-EGSFYTPSENCM
QHAYKWHRDLCHLLLNTYQELYVYFLILMKDIPDFPRMKL-DKLAVEETLSLLCSELQMM
NNPEKIAE--QISKDLTWLCS-HLLE

PF12394 // ENSGT00390000007885_1_Domain_1 (327, 380)

LWTQFLEVVSMNPDVTTYLNKEHHALRVRRFSEA
F--FYMEHQKLNVLTFQES

ENSGT00390000007885_1_Linker_1_2 (380, 1464)

VIQRQSQIALDVRNSEYFTSMPPLPAECLDIDGDWNTLPVI
FEDRYVECPRK-GH--YL-------GISP--NVISPVK--TSQKVEQKEKEKSQ------
-------------------QS--NANATSERTF--REDAF-LP-----------------
--------------WNFEVDYLCPVTGGDVPM-------DRYSPPSS---V---------
S-QVYLTIGETQDEMG-LP-------EESPA----PCA----------------------
---------------VDPATDFR------------------------PIVLTHSVPDLSR
S--EQTVAGDSNLASCLTYIEMNPSNKHPDNA-----EPGLVVAPHYETSTPIDNYIRTV
SDEAAAF----------PPPENVVSTDKVVSH--D--------LSKKENQENK-------
----TTLLSLRHHPVNSTDS----FSPMPRDPLDVKSLPRDPKSNEREVLSALSGTIKRS
SSVISDSGIESEPSSVAWSEARSRVLELPSDREVLHQLVRRHAIHRNSLEGGHTESNTSL
PSGIQASLTSISSLPFEEEEREVA-LNKLTKSVSAPQISSPEELAEDNDISKSNQGNLET
LDGHFQKSLEENQHEGRHINSIRNFPGFQNDP--------------PKHDCEVFPSLVE-
-MAYNTD---HPQEDKGYMDLAKVNDNPDFLFGHC--------SFTYSEPVGNEKPFVGG
A---EYSSTAQTKELTL-DTLHVSKVDTIQDDVSN---KDRLENPQTGSEVS--KTKNDI
FSN--ISISVIENFPQSIHQV--SE---F-PCSSSTE-----TIRPDSNKDKRRD--SCT
GDDV-PTQE---------GCHILQEVDLNEV----VMVNHS----PQVHSIDYQCFENFE
SKQVANSNNFHLASTEALTLDTRKTVEVVNLSVSCTATCLPFSSVVKEAPAKAGLSSKQN
AFPITHQPVGSFGVVSCDARALEEEVNERMFS----FYQAKEKFKEELNNEECLYSDLSV
LASDLPYFPPEEEEENLEDGIHL

PF07819 // ENSGT00390000007885_1_Domain_2 (1464, 1583)

VICVHGLDGNSADLRLVKTFIELGLPGGKLDFLMSER
NQ-SDTFADFDTMTDRLLDEIIQHIQLYNLS-ISRI--SFIGHSLGNII-IRSVLTRPRF
RYYLNKLHTFLSLSGPHLGTLYNNSALVSTGLWLMQKLKKSGSLLQLTFRDNTDLRKCFL
YQLSQKTGLQYFKNVVLVASPQDRYVPFHSARIEMCKMALKDRHTGPVYVEMINNLLQPL
IEAKDCTVIRHNVFHSLPNTANALIGRAAHIAVLDSELFLEKFF---LVT-GLNYFK---
---------

MSEIQGTVEFSVELHKFYNVDLFQRGYYQIRVTLKVSSRIPHRLSASIAGQTESS----S
LHSACVHDSTVHSRVFQILYRNEEVPINDAVVFRVHLLLGGERMEDALSEVDFQ

PF12394 // ENSGT00390000007885_1_Domain_0 (115, 177)

LKVDLH
FTDSEQQ-LRDVAGAPMVSSRTLGLHFHPRNGLHHQVPVMFDYFHLSVISVTVHAALVAL
QQPLISFTHPGRGSWLGKGGPDTGQEQSIISLENLVFGAGYCKPTSS-EGSFYITSENCM
QHAHKWHRDLCLLLLHAYRGLRLHFLVIMRDIPELPHTEL-EALAVEETLSQLCSELQML
NNPEKIAE--QISKDLAWLTS-HMMALWTQFLDTVTLHSQVTTYLTQEHHTLRVRRFSEA
F--FYMEHQKLAVLTFQENLIQTHSQLSLDIRNSEYLTSMPPLPAECLDIDGDWNTLPVI
FEDRYVDCPAT-EH--NL-------SVYP--NFDVPVT--SPTIMNLK------------
------------E-K----ED--NCMVNGNLSF--REDLV-LST--LKP--SQMD-----
---------------SDEEVIRCPELAENVAT-------QNHMDVCS---E---------
S-QVYIAIGEFQNKAG-VP-------EDEC------------------------------
--------------WTGQTSDAGTHPVAD--------VDTSRRS---PGP----------
---------EDGQAPVLTYIDIKSSNKNPSRA-----EPLVAFNAQHENRSSRDKYGLDR
TGLSKVVVG--------GSHQNAISSDKTTLH--ELS---T--LGKGIDQEGK-------
----MVLLSLKLTP---SEPCDP-LNSTVREPLDIRSSLKDSHTEDQEELSVLSGVIKRS
SSIISDSGIESEPSSVAWSEARSRALELPSDREVLHPFVRRHALHRNSLEGGHTESNTSL
PSGIQASLTSISSLPFEEDEREVA-LTKLTKSVSAPHISSPEEAAEDADTKQQGGGFAEP
SDMHSKS------QGSPGPCSQ-LSGDSG-----------------TQDA-GADHPLVE-
-IVLDAD----NQQGPGYIDIPKGKGKQFDAQGHC-----------------LPDGRTEN
T--PGVET----KGLNL-KIPRVIALENPRTRSLH---RALVETPKGIPKDL--NVGQPA
LSSSG--ISEVEGLSQ--HQV--PE---L-SCTSAA-----DAINMNSRGQQSQSGSPCI
MDDTAFN-R---------GANAFPEAKHKAG----TVCPT------VTHSVHSQVLKNQE
LKAGTSIMGSHLTSAETFTLDSLKAVEVVNLSVSCTATCLPFSSVPKETPARAGFSSKQT
LFPITHQPLGSFGVVSTHSSTLDEEVSERMFS----FYQAKEKFKKELKIEGFLYSDLTV
LASDIPYFPPEEEEENLE

PF05057 // ENSGT00390000007885_1_Domain_2 (1459, 1657)

DGIHLVVCVHGLDGNSADLRLVKTFIELGLPGGKLDFLMSEK
NQ-MDTFADFDTMTDRLLDEIIQHIQLYNLS-ISRI--SFIGHSLGNII-IRSVLTRPRF
RYYLNKLHTFLSLSGPHLGTLYNNSTLVSTGLWLMQKLKKSGSLLQLTFRDNADLRKCFL
YQLSQKTGLQYFKNVVLVASPQDRYVPFHSARIEMCKTALKDRHTGPVYAEMINNLLGPL
VEAKDCTLIRHNVFHALPNTANTLIGRAAHIAVLDSELFLEKFF---LVA-GLNYFK---
---------

MSEVQGTVEFSVELHKFHNVDLFQRGYYQVRVTLKVPSRIPHRLSAKIGGQKENS----Q
LGSACVQENTVNSRIFQILYRNEEIVINESMTFQVHLLLDGERVEDALSEVEFQ

PF12394 // ENSGT00390000007885_1_Domain_0 (115, 178)

LKLDLH
FTDSEQQ-ARDASGMPTISSRTLGLHFQPRSGLHHHVPVMFDYFHLSVISVTIHASL

ENSGT00390000007885_1_Linker_0_1 (178, 327)

VAL
QQPLISFTRPGKGSWLGKGSPEGSSEPSIMSLESLVFGAGYCKPSFS-EGSFYTPSENCM
QHAYKWHRDLCHLLLNTYKELHIYFLILMKDIPDFPRKKL-EKLAVEETLSLLCSELQLM
NNPEKIAE--QISKDLTWLCS-HLLE

PF12394 // ENSGT00390000007885_1_Domain_1 (327, 380)

LWTQFLEVVSLNPEVTTYLNKEHHALRVRRFSEA
F--FYMEHQKLSVLTFQES

ENSGT00390000007885_1_Linker_1_2 (380, 1464)

VIQKQSQIALEVRNSEYFTSMPPLPAECLDIDGDWNTLPVI
FEDRYVECPGK-GN--NL-------KHFP--NAGAAVK--TTLKAGQKEKEK----D---
-----------------RLSL--ANATSEKTTY--REDAS-LP-----------------
--------------SSSGPEYMCPGTSGEVSV-------DTYLPYSS---E---------
S-QVYLTIGESQDEMG-LL-------EEHPTVS---------------------------
--------------AEDPGTDFKPIVLAHP------------------------AIDMSR
P--EQNVAGDNNLASCLTYIEMNPSNKHPDNG-----EPGLVIATHYETRSPIDNYIRTV
SEEAAAF----------PVPEDVVSTDKVVLN--EVS--------KEENGANK-------
----ATLLSKKHCPVSLID----PLSPTPRDPLDVKSLARDPNSKEREVLSALSGTIKRS
SSVISDSGIESEPSSVAWSEARSRAVELPSDREVLHQLVRRHAVHRNSLEGGHTESNTSL
PSGIQASLTSINSLPFEEEEREVA-LNKLTKSVSAPQINSPEELAEDNGISRSDQCNSET
LDGHFQKYLEDNPDESKSIDSIRDFPGFQSDT--------------PKHDCEVCNSLVE-
-MVFDTD---QPQEDKGYMDLAEANENPHFLFGHC--------SFTYSEPVVDETSFV-G
G--AEYSSMAKTKELNL-DIFHVSKVDAIQDDVSN---TDLLETPETGSEIL--KTDSNM
FS--SINISVIEDSPPSPHQV--PE---F-SCSSSTE-----TVRLDTNTEKSRDSS--T
-GDDASTQE---------GSQILQEVDLDEI----TVVHHS----QEIPDNDYQCLENFD
SKPIANSNNFHFASTEALALDTRKAVEVVNLSVSCTATCLPFSSMLKEAPAKGGLSSKQN
PFPITHQPVGSFGVVSCERRNFEEEINERMFS----FYQAKEKFKKELKNEECLYSDLSV
LASDLPYFPPEEEEENLEDGIHL

PF07819 // ENSGT00390000007885_1_Domain_2 (1464, 1587)

VICVHGLDGNSADLRLVKTFIELGLPGGKLDFLMSER
NQ-SDTFADFDTMTDRLLDEIIQHIQLYNLS-ISRI--SFIGHSLGNII-IRSVLTRPRF
RYYLNKLHTFLSLSGPHLGTLYNNSTLVSTGLWLMQKLKKSGSLLQLTFRDNTDLRKCFL
YQLSQKTGLQYFKNVVLVASPQDRYVPFHSARIEMCKMALKDRHTGPVYVEMINNLLQPL
IEAKDCTVIRHNVFHALPNTANALIGRAAHIAVLDSELFLEKFF---LVA-GLNYFK---
---------

MSEVQGTVEFSVELHKFYNVDLFQRGYYQIRVTLKVSSRIPHRLSASIVGQTDSS----S
PHSACVHDSTMHSRVFQILYRNEEVPINDAVIFRAHLLLDGERVEEAVSEVDFQ

PF12394 // ENSGT00390000007885_1_Domain_0 (115, 177)

LKVDLH
FTDSEQQ-LRDMAGVPVISSRVLGLHFHPRRGLHHQVPVMFDYFHLSVISVTIHAALVAL
QQPLISFTRPGRGSWLGKGGPDTGPEQSSLSLENLVFGAGYCKPTSS-EGSFYVPSENCM
HHAYKWHRELCLLLLHAYRGLRAYFLTILRDIPELPRMEL-ESLAVEETLSQLCSELQML
NNPEKIAE--QISKDLAWLAS-HLMALWTQFLDTVTLHSQVTTYLTQEHHTLRVRRFSEA
F--FYMEHQKLAVLTFQENLIQTHSQLSLDIRNSEYLTTMPPLPAECLDIDGDWNTLPVI
FEDRYVDCPAT-GC--NL-------NIYP--NFDVPAT--SPAIINLN------------
------------N-R----EE--NLVVNRKSPL--RENLV-LAS--MKP--PPTD-----
---------------SDEEVLRCPGPSKNVAT-------PSHMDVCS---E---------
S-QVYLTVGEFQSKAG-VP-------EVGH------------------------------
--------------QTGPRSDVGGHPLAD--------EDLPRRS---PGP----------
---------EDGQAPALTYIDVKSSNKNPFRA-----EPTVLTGAQHESGCSRDKHGLGR
TERTKGVAG--------GGHHSAVSSEKTTLH--ELS---S--LGKGVDQGSK-------
----VVLLSLKVTP---SEPCEP-LNSSLRDPLDIKGSPKDPQAEEKEDVCVLSGVIKRS
ASIISDSGIESEPSSVAWSEARSRTLELPGDRDFLHQLVRRHALHRNSLEGGHTESNTSL
PSGIQASLTSISSLPFEEEERELA-LTKLTKSVSAPQISSPEESAEDADSTRHRGGPSET
SAVPTES------TSPSGRCLR-PSDGPA-----------------IQEA-GVNHALVE-
-EVSDAD----NLQGPGYIDIPKGQEDRFDPQGPC-----------------CLDGRTDN
P--PDVET----KGLGL-KIPRLLGLASPGHRALP---RELVETPKGVPGDP--DAGTRA
PLDSS--MLDVESFTH--PKV--PE---V-SCAPCI-----D---VDSAGEQS--SSLGV
MEDTAPS-R---------GADTFPEDDHEAG----T-GSA------VTQSIPSPVTGNQE
PRPGTSIMLSHVTSAETFSLDSLKAVEVVNLSVSCTATCLPFSSVPKETPARAGFSSKQT
PFPITHQPLGSFGVVPNHSRKLEEEVSERMFS----FYQAKEKFKKELKIDGFLYSDLSV
LASDIPYFPPEEEEENLE

PF05057 // ENSGT00390000007885_1_Domain_2 (1459, 1657)

DGIHLVVCVHGLDGNSADLRLVKTFIELGLPGGKLDFLMSEK
NQ-MDTFADFDTMTDRLLDEIIQHIQLYNLS-ISRI--SFIGHSLGNII-IRSVLTRPRF
RYYLNKLHTFLSLSGPHLGTLYNNSALVSTGLWLMQKLKKSGSLLQLTFRDNADLRKCFL
YQLSQKTGLQYFKNVVLVASPQDRYVPFHSARIEMCKTALRDRHTGPVYAEMINNLLRPL
VDAKDCTLIRHNVFHALPNTANTLIGRAAHIAVLDSELFLEKFF---LVA-GLNYFK---
---------

MSEVQGTVEFSVELHKFYNVDLFQRGYYQIRVTLKVSSRIPHRLSASIAGQTESS----S
LRSACVHDSTLHSRVFQILYRNEEVPINDAVIFQAHLLLDGERVEDALSEVDFQ

PF12394 // ENSGT00390000007885_1_Domain_0 (115, 177)

LKVDLH
FTESEQQ-LRDVAGAPVISSRTLGLHFHPRKGLHHQVPVMFDYFHLSVISVTIHAALVAL
RQPLISFTRPGRGSWLSRGGPDMGQEQSIISLENLVFGAGYCKPTSS-EGSFYVPSENCM
QHAHKWHRDLCLLLLRAYRGLRLYFLLIMRDVPELPHMEL-EALAVEETLSQLCSELQML
NNPEKIAE--QISKDLAWLAA-HLMALWTQFLDTVTLHSHVTTYLTQEHHTLRVRRFSEA
F--FYMEHQKLAVLTFQENLTQSHSQLSLDIRNSEYLTSMPPLPAECLDIDGDWSTLPVI
FEDRYVDCPGT-GH--NL-------SVYP--NFDISAT--SPTIQNLK------------
------------K-K----EE--NHIVNRNVPF--RDNLV-LST--VKP--AQMD-----
---------------SHEEVIRHPEPDENVTT-------QNHVDVRS---E---------
S-QVYLTIGEFQDKAG-TH-------ELES------------------------------
--------------GAGQRADVGTCPLAD--------ANMSRRS---PGP----------
---------EDGQAPALTYIDVKSSNKNPHRA-----EPMVVVSAQHESRSSRDKCGSDR
TGLSKVVAG--------ENHQNAISSEKTVLR--ELS---T--LGKGAEQETK-------
----MVLLRLKPIA---SEPCGP-PNSTLREPLDSRSSLKDPHTEEQEELSVLSGVIKRS
SSTISDSGIESEPSSVAWSEARSRALELPSDREVLHPFVRRHTLHRNSLEGGHTESNVSL
PSGIQASLTSISSLPFEEEERELA-LTKLTKSVSAPQISSPEEAANGKDNIQQGRGFAEP
SDMDLKS------KDSPGHCSH-LCRGSR-----------------IEDA-RVNHSFVE-
-VDLDAD----NQQGPGYIDIPKGKRSQCDPQGHC-----------------HPDGRTEN
A--TSVET----KGLNL-KTSRIIALENTRTRSLH---RALAGAPKGMPTDF--DVGKRA
LSSDG--ISEVEGISH--HKV--PE---M-SCTSAV-----DAMELSSTGKQNSS--PHV
VNDTAFN-R---------AVTAFSEGEHKAG----TVCPT------VTHSIHPKVLRNQE
PKAGPSIMGSPLTSTETFTLENLKAVEVVNLSVSCTATCLPFSSVPKETPARAGFSSKQT
SFPITHQPVGSFGVVSTQSSKLEEEASERMFS----FYQAKEKFKKELKIEGFLYSDLSV
LASDIPYFPPEEEEENLE

PF05057 // ENSGT00390000007885_1_Domain_2 (1459, 1657)

DGIHLVVCVHGLDGNSADLRLVKTFIELGLPGGKLDFLMSEK
NQ-MDTFADFDTMTDRLLDEIIQHIQLYNLS-ISRI--SFIGHSLGNII-IRSVLTRPRF
RYYLNKLHTFLSLSGPHLGTLYNNSALVSTGLWLMQKLKKSGSLLQLTFRDNADLRKCFL
YQLSQKTGLQYFKNVVLVASPQDRYVPFHSARIEMCKTALKDRHTGPVYAEMINNLLGPL
VEAKDCTLIRHNVFHALPNTANTLIGRAAHIAVLDSELFLEKFF---LVA-GLNYFK---
---------

------------------------------------------------------------
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------------------------------------------------------------
-------------------------------S----FYQAKEKFKKELKIEGFLYSDLSV
LASDTPYFPPEEEEENLE

PF05057 // ENSGT00390000007885_1_Domain_2 (1459, 1657)

DGIHLVVCVHGLDGNSADLRLVKTFIELGLPGGKLDFLMSEK
NQ-MDTFADFDTMTDRLLDEIIQHIQLYNLS-ISRI--SFIGHSLGNII-IRSVLTRPRF
RYYLNKLHTFLSLSGPHLGTLYNNSTLVSTGLWLMQKLKKSGSLLQLTFRDNADLRKCFL
YQLSQKTGLQYFKNVVLVASPQDRYVPFHSARIEMCKTALKDRHTGPVYAEMINNLLGPL
VAAKDCTLIRHNVFHALPNTANTLIGRAAHIAVLDSELFLEKFF---LVA-GLNYFK---
---------

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------------------------------------------------------------
-------------------------------S----FYQAKEKFKKELKIEGFLYSDLTV
LASDIPYFPPEEEEENLE

PF05057 // ENSGT00390000007885_1_Domain_2 (1459, 1657)

DGIHLVVCVHGLDGNSADLRLVKTFIELGLPGGKLDFLMSEK
NQ-MDTFADFDTMTDRLLDEIIQHIQLYNLS-ISRI--SFIGHSLGNII-IRSVLTRPRF
RYYLNKLHTFLSLSGPHLGTLYNNSTLVSTGLWLMQKLKKSGSLLQLTFRDHADLRKCFL
YQLSQKTGLQYFKNVVLVASPQDRYVPFHSARIEMCKTALKDRHTGPVYAEMINNLLGPL
VEAKDCSLIRHNVFHALPNTANTLIGRAAHIAVLDSELFLEKFF---LVA-GLNYFK---
---------

MCEVQGTVEFSVELHKFYNVDLFQRGYYQIRVTLKVSSRIPHRLSASIVGQTESS----S
LHSASVHESSLHSRVFQILYRNEEVFINDAVIFRAHLLLDSERVEDALSEVDFQ

PF12394 // ENSGT00390000007885_1_Domain_0 (115, 177)

LKVDLH
FTDSEQQ-LRDVTGAPMISSRTLGLHFHPRRGLHHQVPVMFDYFHLSVISVTIHAALVAL
QQPLISFTRPGRGSWLGKGGPDAGQEQSIISLENLVFGAGYCKPTSS-EGSFYVPSENCV
QQAHKWHRDLCLLLLQAYQGLRLYFLVIMRDIPELPHMDL-EALAVEETLSQLCSELQVS
RE---------------WI-----------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
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---------

MSEVQGTVEFSVELHKFYNVDLFQRGYYQIRVTLKVSSRIPHRLSASIVGQSESS----S
LHSACVHESAVHSRVFQILYRNEEVSINDAMLFRVHLLLDGERVEDALSEVEFQ

PF12394 // ENSGT00390000007885_1_Domain_0 (115, 177)

LKVDLH
FTDSEQQ-LRDVTGTPMISSRTLGLHFHPRRGLHHQVPVMFDYFHLSVISVAIHAALVAL
QQPLISFTRPGRGSWLGKGGPDTGPEQPTISLENLVFGAGYCKPTSS-EGSFYVPSENCI
QHAHKWHRDLCLLLLHAYQGLRLYFLVIMRDIPELPTMEL-EALAVEETLSQLCSELQML
NNPEKIAE--QISKDLAWLAS-HLMALWTQFLDTVTLHSQVTTYLTQEHHTLRVRRFSEA
F--FYMEHQKLAVLTFQENLIQTHSQLSLDIRNSEYLTSMPPLPAECLDIDGDWNTLPVI
FEDRYVDCPVS-GH--NL-------RVYP--NFDVPVT--SPAILNLK------------
------------G-E----EK--N-LINQNSSS--RKDIP-LST--TEA--PQLG-----
---------------SDEDVTRHPEVQENVPP-------WNPIDVCS---E---------
S-QVYLTIGEFQNRAG-IP-------EVEC------------------------------
--------------WTGPRPDAVKDSLTD--------TDMCSRS---PGP----------
---------DEGQTPALTYIDVQSSNKYCPRA-----ELVQGINVQHEHRSSRESYGIVK
TVPSKVVAG--------TSQNNSISLNQTAAL--ELR---S--LGRGVNQDGK-------
----PVLLSLKLTP---AEPCDP-PSTALREALDTKPSQP-DHAEEPEDLSVLSGVIKRS
ASIISDSGIESEPSSVAWSEARSRALELPSDRDVLHQVVRRHAHHRNSLEGGHTESNTSL
PSGIQASLSSISSLPFEEEEREMA-LNKLTKSVSAPQISSPEDSAEGADTIKNTAGFSED
LDLSSKD------NSSPRHTSL-SYGGPG-----------------VQDV-RSGHSLAD-
-IALDSD----RPQGPGYMDIPNGKGNHSDLQEPC-----------------CLDGMAET
P--LHVET----KGLNL-KIPCTIVLENSKSRSFH---RAAVETAKGKPEEL--SMSKHV
LSNNS--ISEVRAASH--HRV--PE---I-SCSPAV-----EAVNLNSTGVQNSS--LSV
NDTMTLN-R---------RHNASLEAKHEAG----TVCPT------VTHTIASQVSRNQE
LKTGTSISGSHLNSTEAFTLDSLKAVEVVNLSVSCTATCLPFSSVPKETPARAGLSSKQN
PAPITHQPLGSFGVVSTYSSKLEEEVSERMFS----FYQAKEKFKKELKIEGFLYSDLSV
LASDIPYFPPEEEEENLE

PF05057 // ENSGT00390000007885_1_Domain_2 (1459, 1657)

DGIHLVVCVHGLDGNSADLRLVKTFIELGLPGGKLDFLMSEK
NQ-TDTFADFDTMTDRLLDEIIQHIQLYNLS-ISRI--SFIGHSLGNII-IRSVLTRPRF
RYYLNKLHTFLSLSGPHLGTLYNNSTLVSTGLWLMQKLKKSGSLLQLTFRDNADLRKCFL
YQLSQKTGLQYFKNVVLVASPQDRYVPFHSARIEMCKTALKDRHTGPVYAEMINNLLGPL
VEAKDCTLIRHNVFHALPNTANTLIGRAAHIAVLDSELFLEKFF---LVA-GLNYFK---
---------

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-------------------------------S----FYQAKEKFKKELKIEGYLYSDLSV
LASDIPYFPPEEEEENLE

PF05057 // ENSGT00390000007885_1_Domain_2 (1459, 1657)

DGIHLVVCVHGLDGNSADLRLVKTFIELGLPGGKLDFLMSEK
NQ-MDTFADFDTMTDRLLDEIIQHIQLYNLS-ISKI--SFIGHSLGNII-IRSVLTRPRF
RYYLNKLHTFLSLSGPHLGTLYNNSTLVSTGLWLMQKLKKSGSLLQLTFRDNADLRKCFL
YQLSQKTGLQYFKNVVLVASPQDRYVPFHSARIEMCKTALRDRHTGPVYAEMINNLLGPL
VEAKDCTLIRHNVFHALPNTANTLIGRAAHIAVLDSELFLEKFF---LVA-GLNYFK---
---------

MSEVQGTVEFSVELHKFYNVDLFQRGYYQIRVTLKVSSRIPHRLSASVVGQTDGN----S
LHSACAHENAVHSRIFQILYRNEEVPINDAVIFRAHLLLDGERVEEALSEVDFQ

PF12394 // ENSGT00390000007885_1_Domain_0 (115, 177)

LKVDLH
FTDSEQQ-LRDVAGAPLISSRTLGLHFHPRRGLHHQVPVMFDYFHLSVISVTIHAALVAL
QQPLISFTRPGRGSWLGKGGPDAGPEQSSLSLENLVFGAGYCKPTSS-EGSFYVPSENCM
QHAHKWHRELCFLLLHAYRGLRAYFLVIMRDVPELPHTEL-ESLAVEETLSQLCSELQVL
NNPEKIAE--QISKDLAWLTS-HLMALWTQFLDTVTLHSQVTTYLTQEHHTLRVRRFSEA
F--FYMEHQKVAVLTFQENLIQTHSQLSLDIRNSEYLTTMPPLPAECLDIDGDWNTLPVI
FEDRYVDCPAT-GH--SL-------SVSP--NFDVQT---SPAIMNLK------------
------------D-R----EE--SPVVNRKSPF--REDLV-SPA--MKP--PQMD-----
---------------SDEEVLRCPEADDSAAT-------PKHADVCS---E---------
S-QVYLTIGEVQNKAG-LP-------EDEC------------------------------
--------------WAGPRADVGTRPLAD--------EDLPRRR---PGP----------
---------EDGQPPVLTYIDVKSSNKDPCGP-----EPTVVVSAQHESGHSRDNYEPAR
TVPGKEVSG--------TSRPHAISSEKTTLR--ELS---P--LGKVADREGK-------
----VVLLSLKLIP---SEPCDP-LNSALRDPLDVRASPKDPPSEEQEEVSVLSGVIKRS
SSVVSDSGIESEPSSVAWSEARSRAPELPSDREALQHLLRRHGLHRNSLEGGHTESNTSL
PSGIQASLTSISSLPFEEEERELA-LTKLTKSVSAPQISSPEESAGDTDTMQQGGPLAES
CTVPVET------IDSPGSRTR-DAG-------------------------------AQ-
-VVSGAD----NQQGPGYIDIPKGKESQSEPQGPC-----------------CLDGRTEN
P--PGVET----KGLHL-KIPRIIALENPGNGSFP---RVLKETPKGMPEDL--KLEKGA
GSHGS--ISDDETVAH--RTV--PA---L-NYTAVA-----DAVDLGSAGKQS--SSPCI
MDDAEFS-K---------GANAVLEAGREAG----TACPT------VTHSVHSQVLGDQE
PRAGTSVMVSHLPPTETFTLDSLKAVEVVNLSVSCTATCLPFSSVPKETPARAGFASKQT
PLPITHQPLGSFGVVSTHSSKLEEEVSERMFS----FYQAKEKFKKELKIAGFLYSDLSV
LASDIPYFPPEEEEENLE

PF05057 // ENSGT00390000007885_1_Domain_2 (1459, 1657)

DGIHLVVCVHGLDGNSADLRLVKTFIELGLPEGKLDFLMSEK
NQ-VDTFADFDTMTDRLLDEIIQHIQLYNLS-ISRI--SFIGHSLGNII-IRSVLTRPRF
RYYLNKLHTFLSLSGPHLGTLYNNSTLVSTGLWLMQKLKKSGSLLQLTFRDNADLRKCFL
YQLSQKTGLQYFKNVVLVASPQDRYVPFHSARIEMCKTALKDRHTGPVYAEMINNLLRPL
VEAKDCTLIRHNVFHALPNTANALIGRAAHIAVLDSELFLEKFF---LVA-GLKYFK---
---------

MSEIQGTVEFSVELHKFYNVDLFQRGYYQIRVTLKVSSRIPHRLSASIAGQTESS----S
LHSACVHDSTVHSRVFQILYRNEEVPINDAVVFRVHLLLGGERMEDALSEVDFQ

PF12394 // ENSGT00390000007885_1_Domain_0 (115, 177)

LKVDLH
FTDSEQQ-LRDVAGAPMVSSRTLGLHFHPRNGLHHQVPVMFDYFHLSVISVTVHAALVAL
QQPLISFTRPGRGSWLGKGGQDTGQEQSIISLENLVFGAGYCKPTSS-EGSFYITSENCM
QHAHKWHRDLCLLLLHAYRGLRLHFLVIMRDIPELPHTEL-EALAVEETLSQLCSELQML
NNPEKIAE--QISKDLAWLTS-HMMALWTQFLDTVTLHSQVTTYLTQEHHTLRVRRFSEA
F--FYMEHQKLAVLTFQENLIQTHSQLSLDIRNSEYLTSMPPLPAECLDIDGDWNTLPVI
FEDRYVDCPAT-GH--NL-------SVYP--NFDVPVT--SPKIMNLK------------
------------E-K----ED--NCMVNGNLSF--REDLV-LST--LKP--SQMD-----
---------------SDEEVIRCPELAENVAT-------QNHMDVCS---E---------
S-QVYITIGEFQNKAG-VP-------EDEC------------------------------
--------------WTGQTSEAGTHPMAD--------VDTSRRS---PGP----------
---------EDGQAPVLTYIDVKSSNKNPSRA-----EPLVAFNAQHENRSSRDKYGLDR
TGLSKVVVG--------GSHQNAISSDKTTLH--ELS---T--LGKGIDQEGK-------
----MVLLSLKLTP---SEPCDP-LNSTLREPLDIRSSLKDSHTEEQEELSVLSGVIKRS
SSIISDSGIESEPSSVAWSEARSRALELPSDREVLHPFVRRHALHRNSLEGGHTESNTSL
PSGIQASLTSISSLPFEEDEREVA-LTKLTKSVSAPHISSPEEAAEDADTKQQGGGFAEP
SDMYSKS------QGSPGPCSQ-LCGDSG-----------------TQDA-GADHPLVE-
-IALDAD----NQQGPGYIDIPKGKGKQFDAQGHC-----------------LPDGRTEN
T--PGVET----KGLNL-KIPRVIALENPRTRSLH---RALVETPKGIPKDL--NVGQPA
LSNSG--ISEVEGLSQ--HQV--PE---L-SYTSAA-----DAINMNSTGQQSQSGSPCI
VDDTAFN-R---------GANAFLEAKHKAG----TVCPT------VTHSVHSQVLKNQE
LKAGTSIMGSHLTSAETFTLDSLKAVEVVNLSVSCTATCLPFSSVPKETPARAGFSSKQT
LFPITHQPLGSFGVVSTHSSTLDEEVSERMFS----FYQAKEKFKKELKIEGFLYSDLTV
LASDIPYFPPEEEEENLE

PF05057 // ENSGT00390000007885_1_Domain_2 (1459, 1657)

DGIHLVVCVHGLDGNSADLRLVKTFIELGLPGGKLDFLMSEK
NQ-MDTFADFDTMTDRLLDEIIQHIQLYNLS-ISRI--SFIGHSLGNII-IRSVLTRPRF
RYYLNKLHTFLSLSGPHLGTLYNNSTLVSTGLWLMQKLKKSGSLLQLTFRDNADLRKCFL
YQLSQKTGLQYFKNVVLVASPQDRYVPFHSARIEMCKTALKDRHTGPVYAEMINNLLGPL
VEAKDCTLIRHNVFHALPNTANTLIGRAAHIAVLDSELFLEKFF---LVA-GLNYFK---
---------

MSEIQGTVEFSVELHKFYNVDLFQRGYYQIRVTLKVSSRIPHRLSASIAGQTESS----S
LHSACVHDSTVHSRVFQILYRNEEVPINDAVVFRVHLLLGGERMEDALSEVDFQ

PF12394 // ENSGT00390000007885_1_Domain_0 (115, 177)

LKVDLH
FTDSEQQ-LRDVAGAPMVSSRTLGLHFHPRNGLHHQVPVMFDYFHLSVISVTVHAALVAL
QQPLISFTRPGRGSWLGKGGPDTGQEQSIISLENLVFGAGYCKPTSS-EGSFYITSENCM
QHAHKWHRDLCLLLLHAYRGLRLHFLVIMRDIPELPHMEL-EALAVEETLSQLCSELQML
NNPEKIAE--QISKDLAWLTS-HMMALWTQFLDTVTLHSQVTTYLTQEHHTLRVRRFSEA
F--FYMEHQKLAVLTFQENLIQTHSQLSLDIRNSEYLTSMPPLPAECLDIDGDWNTLPVI
FEDRYVDCPAT-GH--NL-------SVYP--NFDVPVT--SPTIMNLK------------
------------E-K----ED--NCMVNGNLSF--REDLV-LST--IKP--SQMD-----
---------------SDEEVIKCPELAENVAT-------QKHMDVCS---E---------
S-QVYITIGEFQNKTG-VP-------EDEC------------------------------
--------------WTGQTSDAGTHPMAD--------VDTSRRS---PGP----------
---------EDGQAPVLTYIDVKSSNKNPSRA-----EPLVAFNAQHENRSSRDKYGLDR
TGPSKVVVG--------GSHQNAISSDKTTLY--ELS---T--LGKGIDQEGK-------
----MVLLSLKLTP---SEPCDT-LNSTVREPLDIRSSLKDSHTEEQEELSVLSGVIKRS
SSIISDSGIESEPSSVAWSEARSRALELPSDREVLHPFVRRHALHRNSLEGGHTESNTSL
PSGIQASLTSISSLPFEEDEREVA-LTKLTKSVSAPHISSPEEAAEDADTKQQGGSFAEP
SDMHSKS------QGSPGPRSQ-LSGDSG-----------------TQDA-GEDHPLVE-
-IVLDAD----NQQGPGYIDIPKGKGKQFDDQGHC-----------------LPDGRTEN
T--PGVET----KGLNL-KIPRVIALENPRTRSLP---RALVETPKGIPKDL--NVGQPA
LSNSG--ISEVEGLSQ--HQV--PE---L-SYTSAA-----DAINMNSTGQQSQSGSPCI
MDDTAFN-R---------GVNAFPEAKHKAG----TVCPT------VTHSIHSQVLKNQE
LKAGTSIMGSHLTSAETFTLDSLKAVEVVNLSVSCTATCLPFSSVPKETPARAGFSSKQT
LFPITHQPLGSFGVVSTHSSTLDEEVSERMFS----FYQAKEKFKKELKIEGFLYSDLTV
LASDIPYFPPEEEEENLE

PF05057 // ENSGT00390000007885_1_Domain_2 (1459, 1657)

DGIHLVVCVHGLDGNSADLRLVKTFIELGLPGGKLDFLMSEK
NQ-MDTFADFDTMTDRLLDEIIQHIQLYNLS-ISRI--SFIGHSLGNII-IRSVLTRPRF
RYYLNKLHTFLSLSGPHLGTLYNNSTLVSTGLWLMQKLKKSGSLLQLTFRDNADLRKCFL
YQLSQKTGLQYFKNVVLVASPQDRYVPFHSARIEMCKTALKDRHTGPVYAEMINNLLGPL
VEAKDCTLIRHNVFHALPNTANTLIGRAAHIAVLDSELFLEKFF---LVA-GLNYFK---
---------

MSEVQGTVEFSVELHKFYNVDLFQRGYYQIRVTLKVSSRIPHRLSASIVGQTESS----S
LHSACVHDSTVHSRVFQILYRNEEVPINDAVVFRAHLLLDGERVEDALSEVDFQ

PF12394 // ENSGT00390000007885_1_Domain_0 (115, 177)

LKVDLH
FTDSEQQ-LRDVAGAPMVSSRTLGLHFHPRNGLHHQVPVMFDYFHLSVISVTIHASLVAL
QQPLISFTRPGRGSWLGKGGPDTGQEQSIISLENLVFGAGYCKPTSS-EGSFYIPSENCM
QHAHKWHRDLCLLLLHAYRGLRLYFLMIMRDIPELPHMEL-EALAVEETLSQLCSELQML
NNPEKIAE--QISKDLSWLTS-HMMALWTQFLDTVTLHSQVTTYLTQEHHTLRVRRFSEA
F--FYMEHQKLAVLTFQENLIQTHSQLSLDIRNSEYLTSMPPLPAECLDIDGDWNTLPVI
FEDRYVDCPAT-GH--NL-------SVYP--NFDVPVA--SPTIMNLK------------
------------E-K----ED--NCMANSNLSF--REDLD-LST--IKA--SQVD-----
---------------SDEEVIRCPEPAGNAAT-------QNHTDVCS---D---------
S-QVYMTIGEFQSKAG-AS-------EDGC------------------------------
--------------WTSQTSDAGTYPMAD--------VDTSRRS---PGP----------
---------EDGQAPVLTYIDIKSSNKNPSRA-----EPPVAFNAQHEIRSSRDKHGLDR
TGLNKVVAG--------GSHQNVILSDKTTLH--ELS---T--LGKGADQEGK-------
----MVLLGLKLVP---SDPCDP-LSSTLREPLDVRSSLKDSHTEEQEELSVLSGVIKRS
SSIISDSGIESEPSSVAWSEARSRALELPSDREVLHPFVRRHALHRNSLEGGHTESNTSL
PSGIQASLTSISSLPFEEDERELA-LTKLTKSVSAPHISSPEEAAEDIGTKQQDRGVAGP
SDMHSRS------QRSPGPCSQ-LCGDSG-----------------TQDA-GVDHPLVE-
-IVLDAD----NEQSPGYIDIPKGKGKQSDAQEDC-----------------LLDGRTEN
T--PGIET----KGLNL-KIPRVIALETPRTRSLH---RALMETPKGKPKDL--KVGQTA
LSNSG--ISEAEGISQ--HKV--PE---L-SYTSAT-----DAINLNSTGQRSQSGLPCV
MDNTAFD-R---------GVNAFPEVKHKAG----TVCPT------VTHSVHSQVLKNQE
LKAGTSIVGSHLTSAETFTLDSLKAVEVVNLSVSCTATCLPFSSVPKETPARAGFSSKQT
LFPITHQPLGSFGVVSTHSSTLDEEVRERMFS----FYQAKEKFKKELKIEGFLYSDLTV
LASDIPYFPPEEEEENLE

PF05057 // ENSGT00390000007885_1_Domain_2 (1459, 1657)

DGIHLVVCVHGLDGNSADLRLVKTFIELGLPGGKLDFLMSEK
NQ-MDTFADFDTMTDRLLDEIIQHIQLYNLS-ISRI--SFIGHSLGNII-IRSVLTRPRF
RYYLNKLHTFLSLSGPHLGTLYNNSTLVSTGLWLMQKLKKSGSLLQLTFRDNADLRKCFL
YQLSQKTGLQYFKNVVLVASPQDRYVPFHSARIEMCKTALKDRHTGPVYAEMINNLLGPL
VEAKDCTLIRHNVFHALPNTANTLIGRAAHIAVLDSELFLEKFF---LVA-GLNYFK---
---------

MSEVQGTVEFSVELHKFHNVDLFQRGYYQIRAGLKIPSRIPHRLFATIAGQTGDS----S
LCSACIHENNVYSRIFQILYRNEEIVLNESMNFKVHLLLDGERVEDALNEADFQ

PF12394 // ENSGT00390000007885_1_Domain_0 (115, 178)

LKLDLH
FTDSEQQ-LRDVPAIPLISSRTLCLHFHPRRGLHHHVPVMFDYFHLSVVSVTVHASL

ENSGT00390000007885_1_Linker_0_1 (178, 325)

VAL
HQPLISFARPGKGSWLGKGNPEAGPDQSSMSLENLVFGAGYCKPTSS-EGSFYVPSENCM
QHAYKWHKDLCLLLLNAQRGLHTYYTLIMNEIHDLPQLKL-EELSVEETLSQLCMELQLL
SNPEKIAE--QISKDLAWLCS-HL

PF12394 // ENSGT00390000007885_1_Domain_1 (325, 378)

LALWTQFLEVATLHPEVTAYLTQEHHMLRVRRFSEA
F--FYTEHQKPAVLMFQ

ENSGT00390000007885_1_Linker_1_2 (378, 1459)

EGLIQSHAQISTEIRNSDYFTSMPPLPAECLDIDGDWNTLPVI
FEDRYTDMPCKAKCSHIPWAYE------------LGKV--SPPLSNTGSRAT-----RR-
F-PQ-KSVIRIISPACPRCQQ--SAWTSTGTGTRSLSSLK-TGT--QTC--PAKS-----
--TFKITKL-----V---CALKTSNTDSEVPA-------NTQMDV---------------
---------------K-LE-------NEDCASDDA----------SAVIT-----EAAAK
GSNQHSTSQVCTINKEGQRKPENIFVSREETISDSREETISDSE---PGNTEHMSEDFKT
S--EEVVLKDN------ICGNMEPSNKDSHKI-----EPMLIVSAQYDLGKPEDADTKAH
LPVLKALPLHSCEVRSATKEQRGEESEEFTLMSGAIKRSSSLISDSGIESEPSSVAWSDA
RSRGLELPSEREMLQQLEEDREVELTKLTKSVSAPQISSPEEPTEEHEEFTLMSGAIKRS
SSLISDSGIESEPSSVAWSDARSRGLELPSEREMLQQLVRRHAGHRNSLEGGHTDSNTSL
PSGIQASLTSISSLPFEEEDREVE-LTKLTKSVSAPQISSPEEPTEEVDISKRSEGSSGD
SDQNLRSCMETEGKDGKIIMDF---SEGQ-----------------MPTESGQTEHRRH-
-PK--PL----LKH-SSSNAELQGEEKKGFPETCC--------GLENTRPPICPKQLQDN
V--SECLSLESNGECSL-KTPRACNYLDKNIDKVD----PFIEDPKDKLKPDSLKIQQGS
PK---SRISGEESFSQSIKVV--PD---F--CYPVTAPSDTSTEFGSLQGECGRS----L
TEDSPAVYA---------EMQGLQEIELNDSPA--SADPVP----GPHQAERPQEPS---
-----------------SQLESRKAADVVNLSISCTATCLPFSSVLKETPAMAGSSAKQA
ACPITRQPLGSFGVVCSNSEEMDEETNERMLN----FYQAKEKFKKEMKIEGFLYSDLSV
LASDIPYFPPEEEEENLE

PF05057 // ENSGT00390000007885_1_Domain_2 (1459, 1657)

DGIHLVVCVHGLDGNSADLRLVKTFIELGLPGGKLDFLMSER
NQ-TDTFADFDTMTDRLLDEIIQHIQLYNLS-ISRI--SFIGHSLGNVI-IRSVLTRPRF
RYYLNKLHTFLSLSGPHLGTLYNNSTLVSTGLWLMQKLKKSGSLLQLTFRDNADLRKCFL
YQLSQKTGLQYFKNVVLVASPQDRYVPFHSARIEMCKNALKDRHTGPVYAEMINNLLQPL
IGAKDCTLIRHNVFHALPNTANTLIGRAAHIAVLDSELFLEKFF---LVA-GLNYFK---
---------

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---------------------------IIFSS----FYQAKEKFKKELKIEGFLYSDLSV
LASDTPYFPPEEEEENLE

PF05057 // ENSGT00390000007885_1_Domain_2 (1459, 1657)

DGIHLVVCVHGLDGNSADLRLVKTFIELGLPGGKLDFLMSEK
NQ-MDTFADFDTMTDRLLDEIIQHIQLYNLS-ISRI--SFIGHSLGNII-IRSVLTRPRF
RYYLNKLHTFLSLSGPHLGTLYNNSTLVSTGLWLMQKLKKSGSLLQLTFRDNADLRKCFL
YQLSQKTGLQYFKNVVLVASPQDRYVPFHSARIEMCKTALKDRHTGPVYAEMINNLLGPL
VAAKDCTLIRHNVFHALPNTANTLIGRAAHIAVLDSELFLEKFF---LVA-GLNYFK---
---------

MSEVQGTVEFSVELHKFHNVDLFQRGYYQIRAGLKIPSRIPHRLFATIAGQTGDS----S
LCSACVHENNIYSRIFQILYRNEEIILNESMNFRVHLLLDGERVEDALSEADFQ

PF12394 // ENSGT00390000007885_1_Domain_0 (115, 177)

LKLDLH
FTDSEQQ-LRDVPAIPMISSRTLCLHFHPQRGLHHHVPVMFDYFHLSVISVTVHASLVAL
HQPLISFARPGKGSWLGKGNLDTGPDQSSMSLENLVFGAGYCKPTSS-EGSFYVPSENCM
QHAYKWHKDLCLLLLNAQRGLHVYYSLIMKEVPDLPQMKL-EELPVEDTLSQFCAELQLL
SNPEKIAE--QISKDLAWLCS-HLLALWTQFLEVATLHPEVTAYLTQEHHMLRVRRFSEA
F--FYTEHNKLAVLTFQEGLIQSHAQISTEIRNSEYFTSMPPLPAECLEIDGDWNTLPVI
FEDRYMDLPCKDQ---NL-------DTFP--DFEVPAN--TQIDVIDE------------
------------------------------------------------------------
-----------------------------------------KENLAS---N---------
D-ATVEMKGDFGKGTL-LI-------HTDRINGN-PCLY-----SDTEGA-----ALAAK
GLNQHSNSQVCTVNKEGQRKPENICVSSK--------ETTSVSE---LSNTECVSEESKT
C--KEVLLKDSRHSVGITSEEKKSSNKGPHRS-----EPMLIVSAQLECGACGTDGLESR
TEIHKTSES--------GHLENNFSSEPALSE---FT---R--LERTPEPD---------
-----------------SKPLHPVLKALPSHSLEVKLFAKEQRTEECEEFTLMSGVIKRS
SSIISDSGIESEPSSVAWSDARSRALELPSDREILHHLVRRHAIHRNSLEGGHTESNTSL
PSGIQASLTSISSLPFEEEERVVE-LTKLTKSVSAPQISSPEEPVEEVDISKHTEATSGD
SGGYLKSCRERENGDGQLMTDFSVC---Q-----------------LTTESEQLEPRGP-
-S--KPS----AEDSNGNIELQREEAKEDFSETYC--------SLECTKPSACNP-LRDN
D--SEGQSLESNDGCSL-KTPRANNYLDKSIDEFD----KYITDPKDTSKLDSLKIEQDL
YIS--VRKTGEDSFSQSIKLV--PH---I--CNPVSDPSETSTEFGSVQRECNNF----L
ADDSLLVYT---------EMQGLQEIELNDSPA--PADPAA----ESCQDKYPQELDNQE
QKLVANGTGFHSVTMDGVALESRKAVDVVNLSVSCTATCLPFSSVLKETPAMVGFSAKQA
AFPITRQPLGSFGVVSSHSNDVDEDANERMLN----FYQAKEKFKKEMKIEGFLYSDLSV
LASDIPYFPPEEEEENLE

PF05057 // ENSGT00390000007885_1_Domain_2 (1459, 1657)

DGIHLVVCVHGLDGNSADLRLVKTFIELGLPSGKLDFLMSER
NQ-TDTFADFDTMTDRLLDEIIQHIQLYNLS-ISRI--SFIGHSLGNVI-IRSVLTRPRF
RYYLNKLHTFLSLSGPHLGTLYNNSTLVSTGLWLMQKLKKSGSLLQLTFRDNADLRKCFL
YQLSQKTGLQYFKNVVLVASPQDRYVPFHSARIEMCKNALKDRHTGPVYAEMINNLLQPL
IGAKDCTLIRHNVFHALPNTANTLIGRAAHIAVLDSELFLEKFF---LVA-GLNYFK---
---------

MSEVQGTVEFSVELHKFHNVDLFQRGYYQIRAGLKIPSRIPHRLFATIAGQTGDS----S
LCSTCVHENNVYSRIFQILYRNEEIVLNETMNFRVHLLLDGERVEDALNEADFQ

PF12394 // ENSGT00390000007885_1_Domain_0 (115, 178)

LKLDLH
FTDSDQQ-LRDVPAIPMISSRTLCLHFHPHRGLHHHVPVMFDYFHLSVVSVTVHASL

ENSGT00390000007885_1_Linker_0_1 (178, 325)

VAL
HQPLISFARPGKGSWLGKGNLEAGADQSSMSLENLVFGAGYCKPTSS-EGSFYVPSENCM
QHAYKWHKDLCLLLLNAQRGLHTYYTLIMNEIPDLPQLKL-EELSVEETVSQLCMELQLL
SNPEKIAE--QISKDLAWLCS-HL

PF12394 // ENSGT00390000007885_1_Domain_1 (325, 378)

LALWTQFLEVATLHPEVTAYLTQEHHMLRVRRFSEA
F--FYTEHQKPAVLMFQ

ENSGT00390000007885_1_Linker_1_2 (378, 1464)

EGLIQSHAQISTEIRNSDYFTSMPPLPAECLDIDGDWNTLPVI
FEDRYTDMPCK-DQ--NL-------EVFP--DFESPAN--TQMDVKLE------------
------------------------------------------------------------
-----------------------------------------NEDCAS---D---------
D-ATAVMKGGFEKDTP-LI-------HTDRINRNPSCPH-----SSTEA--------AAK
GLNQHSTSQVCTINKEGQRKPENIFVSRE--------ETISDSE---PGNTEHMSEDFKT
S--EEVLLKDNRLGADVVCGDMEPSNKDSHKR-----EPMLIVSAQHECGACGTDGLEDS
TEIHELDEF--------GHPETNFTSSELALN--ELT---T--LGKPEDVDTK-------
----AHLPVLKALP---SHSCEV------------KSVTKEQRSEESEDFTLMSGVIKRS
SSIISDSGIESEPSSVAWSDARSRALELPSDREILHHLVRRHAIHRNSLEGGHTESNTSL
PSGIQASLTSISSLPFEEEEREVE-LTKLTKSVSAPQISSPEEPPEEVDISKHSEATSGD
SDHNLRSCMETEDKDGKIIMDF---S-------------------------EHPNLLLK-
-------------HSSSNT-ELQGDEEKGFPDTCY--------SLENTRPPICPNQLQVN
V--SECLSLESNGECSL-KTPRACNYLDKNIDKVD----TCIEDPKDKLNPDSLKVQQ--
----GCRISGEESFSQSIKVV--PD---F--CYLVTAPSDTSTEFGSLRGECGSS----L
ADESPAVCA---------ELQGLQEIELNDSSA--SAEPAA----GSHQAEHPQEPNSQE
NKLIVNGTGFPLAATEGVALESRKAADVVNMSISCTATCHSLFFCVQRDPAVAGSSAKQA
AFPITRQPLGSFGVVCPNSDEMDEETNERMLN----FYQAKEKFKKEMKIEGFLYSDLSV
LASDIPYFPPEEEEENLEDGIHL

PF07819 // ENSGT00390000007885_1_Domain_2 (1464, 1587)

VVCVHGLDGNSADLRLVKTFIELGLPGGKLDFLMSER
NQ-TDTFADFDTMTDRLLDEIIQHIQLYNLS-ISRI--SFIGHSLGNVI-IRSVLTRPRF
RYYLNKLHTFLSLSGPHLGTLYNNSTLVSTGLWLMQKLKKSGSLLQLTFRDNADLRKCFL
YQLSQKTGLQYFKNVVLVASPQDRYVPFHSARIEMCKNALKDRHTGPVYAEMINNLLQPL
IGAKDCTLIRHNVFHALPNTANTLIGRAAHIAVLDSELFLEKFF---LVA-GLNYFK---
---------