Query Results 

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----------STEKACSLSNCTVAKRIGKGKDATVIFEHFRKPVDLF---SQENCPCKAL
TSETDSSSLESSSSHRSVQNG-NSCVFDTYSRHTDN-LSEVGDASQVHTHNSALSLMPTA
NTASG-NGDL-FSVTYLRSILSSISAVLPSQSSTGSSTVITSKLIKDPRLMKREQSMRKQ
NNAAGLSDTLPFDKSVGHGNSEIK-LTCMPASLVSSPETTPADHAL-TNCSDISCFKFSS
ERSYCQTHNMGSREYDSTTVSKIAITEQCKEQ---S-GISFPRYLPNAISNVEKQKYNEE
E--EAQKRSNIPVLTEQSNEPQN---------SFRSE--KNTYSKDYQSHISTASWSSDL
NNVYKVGHKMS-AVFPIQNKGN-LDEYMQNTGMMRTF-ISPEDGS--KCV-NQTCWKETV
N-YFTDKTKSSPIDSCITLDQK--HKECGNLNSLTGNGDKIPVTHKL-QMPK-PPISTTE
DKNELDRAVVELECNLT-PDTGYLLQKHPQYSLEHKD-NIDTNFAMAQGLTELKVVQNN-
QNFINM-TDAFQEAKDIPLDREHFIDRVVSSSASDVSLDTSGGNMIGEYMCIQRENKND-
------EKDCKETSHTK---GNVQDHCLSYDAELSSDLN---LKINSQ-EQR---HE---
---NPNE--YKTD----------NINESEKQDFH-------AN-AVEMREIKSNTKVEIL
NSEECS-TFDSICGKK-GRPATSASSES---EDSMDSIKQRHAP-SDGRSVEHLVST--F
PEI---EVSSVCIASNATKQVVNTTILTLN-TNCEDHQKHQLKETCASEISDLGL-VKHG
IFNCEIDPDKDKLQD-FYQLVN-EN---SILQTYELGSEIEVELEDCNDASL--FPQNID
SQGNHLCEEFE-LYESLKSRIDWEGLFGNSNKEMEAISFARR-EGADPH-STDCNCVSFS
SQKDRRELHNPIFLPDLQVTIT-NLISLRISPTDDSLESKGNFYKCVTESTEPEANE---
-----GKPFGFSIYSQH----SGFSCENKCGDS-VQELEYVSKS-GTSHSSNSS-HRTCV
---SHISG-KPNSNSLSTESCNVT-VINEKSKC-PRKSK-HDFNDTRNKKDMESRNGKRN
LHAS-SRSQNISHKDLRQHETHEKRRKPASYDSSERFSSLSQGRIKTFSQSERHIRNVLD
ILNNEASLCKSKHLSRKLDKAVLHLKKAHRRVHTSLQLISKVGKK-RKGPLPKAYSVICN
NF-WESCDLQGDSWMSERR---SRHFLSKRRYDKQGEKR-LRFDVDESLAPVSKHRSYR-
T------NRERISEYLSRGIMSGHVSSSLTT-FHVREFCDG--LHQSQLPLAYTSQTISQ
L-GYTNSIVRN-ASSSELEHFSET-SGHTLY---PGETVTEKEYQTG-------IDSAKL
GNHSTHN-IK---DITKENNSEDETVVCESNSVSLSSMKEN-ISHSQDK--CDLTCKAN-
---TDIVVSVLDLNKKHFLNVGICEQDNLVS-DGTRNGGTILPVEKCTVLREIE--P---
----SIPTGN----------IPPL-SPILLTAGEEESSLG---ENR--------------
------------------------------LHLKENEVNIT-KHSKLDLMS-VNKESKS-
-CNKNI-------K--PSSNGGSLLLKENVKVP--SKTYMAKYIEEEKMKKIEQAV----
-------YQAVV--------TGYKHQNKILK-EGSFHSHKKIIKNDLTDSCLG-IKNSTL
E-TTALKNIPS-QLS

PF15326 // ENSGT00390000006260_0_Domain_1 (2116, 2382)

KRQ-KVGQMKQ-----QS---------------------------
-D--------CPSK---PATAGTNCRPDLHENSEVPAE-----KKPPTHMQGLKEGHRVA
NYTSRVTELSQILQKADTAVSLKVLEEETKVCQNLLPLFVEAFERKQECSLDQILISRKL
MVEQNLWDNCRFKLKPSAVDTWVELQMAMETIQFIENKKRFLEGKVTFRSLLWYDESLYS
ELLSRPRGYQLQSNFYPAFQRRLKYNAFCELQSYYHQLVEI

ENSGT00390000006260_0_Linker_1_2 (2382, 2603)

LAETKKENNSYYAFLKYKR
QIKECEAIKRHYSDCFDFCLSVPFTCGVNFGDSLADLEALRKSVLKLISMHA-GSPKAHC
YPGKEDHLWIILEVVSSKVSFIKSNEEISIKICLYGLEHIYFDAAKSLVWKEKSQSFPKR
HSE--NRE-METINECAFSKWEKIYDVLSKDLDNES-TPSIGLKEDDMIVSRQSA-LV--
---SLPNCKLNK---AWLSYPD

PF15326 // ENSGT00390000006260_0_Domain_2 (2603, 2724)

ICCISEILDQAKSADLETLQDLTLKCTVHLETLKKYFQ
MLQEDNINNIFITEENVLDIL-NHNHGAVILKPEAIEIYIETIMLSETVHFLKNSIAEKL
HNQRFRGMLWFDWSLLPELVGCQKEMASFSV-DDNQTD-CLWKVIETAISHLKKELCILY
DYGE-AVNCSYALRLFSRELKELLGIKRLLKMSKYSVSTYIDLAPHIACVNYGNTVEELD
HNYNQLFTLLKNIMSVPQKDFGKMVHIMKVLKTIKHMKMIRAKGTKLSTHLLFFQMLRNR
RNTLQ-FSKKEKREMPTTEPEENSSQPDISV-QTPLAAGCTIKNIASSSKKRPVTADKCE
V-SQGKENTDAVSNCKRQKVTMKDVR--NRQKTISKNPRTTESHPIDENKIGSNLPDSLK
RDSA-SPEMVKRPSSTPGLLSPSENIEDTCTPKPESKIELTDSSSGVSEYLAEQQESL-N
GIMK--GNVNFNAAQTN--KKDH-PLVSCDQKDIAA-TCSPDNTP-AQKLHGNPVDH-TQ
ICPSNVRPGNDDSLMPRA-SV---PASHSVRAIHSNLEMN-DTDFEHEDNKILDLSVKDC
T---CTSSPEPVCIQDKIPVLQVNKTQPI---------KDAPNPSIS-PFGSYGSLALDV
NQRAQCTVSEQG---GKNPKVVTQKVGTSWNAPPQSTYTTVYNSSEHSFG-GSYPYYAWC
FYQCSS--SSGTAVTRTYQGMTTYET------PPPMMTAVAS-----AVQNTHFNHSYSE
HFSYFARQQQANAFIPGNGYSPSPMPVSYSYQQPVYSQFSSHQLVPQAAYPYPPNPGVLP
QVPWTYAPWQ-QSSFPPRH--

-------------MEMKEISEQKTLWKMSST----RESLPVTGIEVSPLKKFTIPKIRRA
AGKVYLSPCCTNTREYSFIHETLKQYRLDVSCDLQS-SWQFGDTKLVRNQELEKNFTTKR
S

PF12509 // ENSGT00390000006260_0_Domain_0 (122, 279)

EMRESGRHGRELEEHFCFLALPQRDVEEICQNGLSTKA--STLKILGNPLLGIYIFRHV
DVALNYAHSRSITIENIIIFKV-LFGKVK------KIQPSMDVNKVSLDPCPNFDCHMSR
SVPSLKDTVE-LQAYNSVVYFYEYNILSKPVDKPRQCL

ENSGT00390000006260_0_Linker_0_1 (279, 2116)

PYAVVTVKFIGQKIDIGHLTTP
LRLLATGFPKRLERTCSLNNCTVAKRIGKGKDATVIFEHFGKPVDPF---APENCSCSTQ
NSEINSFNADISNSYENVQSG-NTSILETNSGQSENNLAEIRGTSQGQVYDSGPPFMPND
NKESGNSDH--VFLTYLKDILNVMSAPFPPHNNTGSSTVTTSKFIKDPRLMKKEESMGKQ
NHATGLSEILPFEKNLVD-NAEIN-PSYVLTNSSYSSEVIPHDCAAPSNCLDTTSSKFSF
DDSPSQTHNLGPKDYNCIAP----RIRQYKDQ---G-NFSFPVSLLNV-SELENQKHSED
KAQTAQERNGIPLLIKQSSRPHN---------SYESV---NTYTKDSGGHISEELHSSNF
NTVYQTGHQMS-IVFPPQRKGS-IDECIQNTGKMRNF-TDPEDSY--GYDGKRSLQKETD
N-NFTNETKITPISNYISSCQE--YKNDKTFDSLGGNTDEMLITQEL-EMPE-PPNFTTK
-DDEQDHLALELESNLT---LECLSQKHPQHSIDCEV-SMHTSFVSTQKLREMNLEKTN-
QNCVSIRTDAFQEAKDILQTRELLGNSVTKCHGVEIALDNSNCSKTREYVCVQRKNENKS
VSLEDIQRDCTETPYTE---DEGQAHILSGTAQLNDDKF---LSIHFK-GPRDDDKE---
---NKNKAKEAS-RASSPANNIETVCGNQKQEYHTN--NTLTN-TEDRKKNKNDNREDIS
NSEDVSTTFNFIWREK-DRSPETTL-HS---ADTLAAMKQRDVQ-NTGRNVAHLALTP-F
PES---AGSSVAVASDPAIELANTTLPT------EAHPRYQLKETHSSKSPDFGLLVKQS
IADCEIGMDKNKLQDSCHQPVN-EN---SVLQSFDVASETEVELEEYDDAFL--LQQKRH
SHEDILHEE----HEALKSRINWEGLFGSNNGKMDNLGST-TTEDIAEHHSKNTVTFCSS
Y--Q---KLYPVLLPDLQVRIT-NTFRTTFSPPDDTLSVKNNFYRCLTEATKPGRNKEG-
------KAPGFEIYSKSSCGNSGYPCDSQAGNS-MQDSRLVSKS-EISHFSNLN-HNTDK
---NDMSG-KKSNESFSTEPFNVT-TINGDHQCFFTKSK-MDFNDTRNKKDMESRISQRN
I-RTSFKDHNISHKDTRQHEICEKKRRLSSHDSSECFSSLSQGRMKIFSQSERHIKDVLD
ILNSETSLCKSRCLSRKLNRAVLHLKKAHRRVQTSLQLIAKVGEK-RKGPLPKAYEITCN
NF-WESCDLQGCSSVSERRY--SKHFLSKRKYDRLGK-RASG-----S-VGMSKHKSYK-
R------NREKIAVCHSKKSVTSNVSRSHTT-VHVREFCDEHHHPQSQLSLFSVSQSTSE
P-EYGKSSMKD-SRSSECEPFSEN-TKYLLY---SNEKQSEKENQVNTK-LSNISKCEKL
RNQSAHNKYM-----GKKNNSEVNKVISKSSSVSLSKTKENNVSYSTEK-NYDAICLAHT
KVKTDIFISTLGSNVKLFLNVDTYKGDNSIISDCQSNLKENFPIERWIAPTESYKPSIIT
GNVLMGPFNITLTSNKK-YNILQL-SATPVTDSERESLKSCLGKQRVLAIDYPATPT---
---TVSHRQQIHGRK--VLLKTQQSL-SSSSFMEGNKTNVT-EHSELDLTS-VTEEMKS-
-YGENT-------LKKLSFNDNSLHIKDNIKDL-SEIYIEKQDIQNRKIRKNEQAEKA-K
GSL----HKKSMSE-GSVVETEYKNQKNKILKEKSPHLNTKTVKSNLIDSHLS-IKTTPE
A--VSLSNTVSSQLN

PF15326 // ENSGT00390000006260_0_Domain_1 (2116, 2382)

KSK-KEEKTKI-SSDCQS---------------------------
-G--------CISK---PGIVEIDHMPILHAHSETSKITGIQ--RPTSYVNELKEKYCPV
THRALITELSQILQRADEASSLEILKEETKVCQNILPLFVEAFERKQECSLEQILISREL
LVEQNLWNNCKYKLKPCAIETLVELQMVMETIQFIENKKRLLEGEPTFRSLLWYDETLYS
ELLGRPHGYQLQSSFYPAFQGRLKYNAFCELQNYHNQLIEL

ENSGT00390000006260_0_Linker_1_2 (2382, 2555)

FAETKRESNSYYALLKYRR
QINECEAVMKQRSDCFDFSLSVPFTCGVNFGDSLADLEILRKSTLKLISIYG-DSPTVHS
YPGKQDHLWIIIEMISSKVNFIKSNEAVNIKVSLYGLEHICFDAAKNLVWKKKRQSFSKK
YSPK-NQEVIHKMNERALSKLQKIYDSLSEKSNN

PF15326 // ENSGT00390000006260_0_Domain_2 (2555, 2721)

IP-TSNIELKGDTAITSRKSDNLI--
---TIEKS-------TLVSRPGI-SISEILDQVEFADLKKLQDLTLICTDHLEILKKYFQ
MLQENNVDDIFITEENVLDVLKNHKHEAVILKPEATETYIEIAMLSETVHFLKNSMAKKV
DNQRFRGMLWFDLSLLPQLVHCQEKMVCFSFLEDNPRD-CLRKAIETGISECKKDLDIIY
KNKE-AVNCLYALHLFSRELKELSEIKKLLKKSEYPFPTYIDFVPCIISINYGNTVTELD
HNYSQFSTLLKNTVAVPQKDLGKIAHIMKVMKTIEHMKMICAKNAKLTTTFILCQMLHNK
RSNFQ-FKRKEKVNTLSTIPEENT-RPSTSA-KVPSTSVHIIRDISNSSKRRPSALDKYE
D-S----------ICKKRKVDISHTAEINKEKAVFRCLRTTGFHPQGENKIGWRSSDNLK
RNCV-SSERDEMQGSLCDSLSPLKNSQATYTSESESKIDLTNISPDASKHLSEQQENL-N
SIKK--RNANFGAPETKSYKNDYATFATCDQRSING-TLSKDQDTPSQKLLKNLPDPAQK
TFLSNIKPATDDSLVPNL-SVLSEPISHSLRDIHTNLGIN-GIVLDHQDNELLESSINKS
T---CASFPEPIYIQSRIP--------------------DTLSPSPI-PFGASGSLPCDV
NQTAEYSFSEW---DEENPKVLTQKAATYWNELPQSTYTPVYNSSDHSLG---TPYYAWC
IYHYSS--SSGNATAHTYQGITSYEVQS---PPSGILTTLTS-----TVQTTPSNLVYSQ
YFSYFADQPQANTFVPVNGYFQSQMPISY-FQQPIVSQHASHQPLSQAVYHYYPAPAVLP
EASWIYAPWQ-QQPFQPRH--

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-----YFLLIFTERTCSLNNCTVAKRIGKGKDATVIFEHFRKPVDPF---VEENCSCNVL
NSEINPSNSSISNSYGNMQNG-NISILEAYNEKTENNLAEIRDSSQIHEHDSGVS-LPSD
NRESD-NGDFLLNLTYLKNILSGISAAFPPHNNTGSSTVTTSKLIKDPRLMKREESSEKQ
N-ITVLNEILPFKKSVDYDNSEIN-LSSVPADSVSSPEV-TSDHAILTNCLDVSCFKFSF
DDSQPQTQNT--EDHHRTAPNKITMAEQCKDQ---G-DLSFPIYFSNIVSEVENQKHSEE
KAQRAQEKSNISLLIKQSSEPCN---------SYKSV---STCTEEYNSYISQEPQ----
------------------------------------------------------------
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--------------------------------------------SIAQKLMELKLEKTN-
KNCVSIMPDAFQEAKDISQAKELLIDTVITSHAIETSLDNSNCNKTREYICAQRKSESEP
VSLENIQRDCKEMPHIE---DEGEDHILFYNAQLNNDLY---LNTNFK-WQGYNDNE---
---NEAEE------------EDSNVYGGKKQGFLTN--NTMTN-ISERRENKNYNKVEIL
SSKEFSTTFNLVWEDK-DKSTETALLES---EDTIIAIKQRDMQ-STGRNVEHLDSTA-F
VEI---ADSSVGEASNATVEVASTTMPTLS-TNYEAHQRFEFKDTCF-ESPHFGSLVKHG
ISDCEIDMDKNKLKDSLNQSIN-EN---SVLQSSELQNEIEIESEQ----------YDTH
SHGNVLYEEVEASYEALMSRIDWKSLLGSDNGEKEILESTTKKENIDQHCSKKIICFYSS
TQK---EELHPILLPDLQVRIT-NIYKPGFNPNDDSLVIKDNSYKYITKSTNPEINEE--
-----REAPEFKIYSQPPGENSGYPCEDLFGNS-LPDSGITNEN-ELSHSSDLS-HNTQE
---NHKSE-KQSSGSLSTKP-NIT-VINDKCRYFFSKSK-KDFNDTKSKNDTESRISKRK
L-HASFRDENIS------HEICEKKRKLTNQDSFECFSSLSQGRIKIFSQSERHIRSVLD
ILNSEASLCKSKRLSRTLDKAVLHLKKAHRRVHTSLQLIAKVGEK-RKGPLPKAYAIICN
SF-WESCDLQGYSSVSERRYYSTKHFLSKRKYDKQEEKRTLGFDVDKSLAYVSKHKSYK-
T------NGEKIAKCHSKKRVATSVSRSHTT-IHVSEFYDLEQNPESHLPLFSTSQSTSQ
S-EYDNS-LRH-SRSSELQPFSGR-TECLLY---PDEKLTKKENQIDIKVS--NSEYKKL
ENHSAHNNTK---DVIKDNNSDANKVINEINSVSLNCIKENNPSYNTDR-N-EGTCIAHT
KVKTDIS--VSDSNVKHI-----YEQEN-LSSSCKRNLEVNVSIDKYTTPIESCKPNIIA
GNFLMATPM---------------------------------------------------
-----------------ILLNTEPCSSSNCFLTDEDETNGI-GYSELDLTS-VTEESKS-
-CGENI-------MNKLPSNGSSLLLKDNIRCS-SKKCIAKKDIQARKNSPIEQAEK---
DSI----YKRGTTE-G--LTVKYKNQN--SLKEEPSHLNMKKIKSNPVDSNVS-IKNTAP
E-AVSLSNTISGQPNKRQ--EWGIKV-TDDSQS---------------------------
-R--------CISK---LGIQAINCIPFLHV

PF15326 // ENSGT00390000006260_0_Domain_1 (2192, 2379)

QSE--------------------------
--ASFIAELSQILQRADEASSLQILEEEMKICRNILPLFVEAFERKQECSLEQILISREL
LVEQNLWNNCKYKLKPCAVDALVELQMVMETIQFIENKKRLLKGEPTFRSLLWYDETLYS
ELLCRPRGYQLQSNFYPAFQGRLKYNAFCELQNYRNQL

ENSGT00390000006260_0_Linker_1_2 (2379, 2603)

LAK----TKKNNSYYVFLKYKR
QINECEAILKHCSDCFDFSLSIPFTCGVNCGDSLGDLETLRKSTLKLISKYE-DSPKVYT
YPGKEDHLWIIIDLISSKVKFIKSTEAVTIKISLYGLEHIFFDAAKNLVWKERRKYFSKK
YLQK-NEDVLLKMNECAFSKLQEIHEILSKDLNSEL-TSSIGLETDTMITFGKSHDLV--
---SQENCRFNS---TLLSHPG

PF15326 // ENSGT00390000006260_0_Domain_2 (2603, 2721)

ICYIGEILDQAEIADLKKLQELTLRCTDHLEILKKYFQ
MLQEVNIDDIFITEENVLDMLQNYNHGAIILKPEAIETYIEIVMLSETVHFLKNSMAKKL
DNQRFRGMLWFDFSLLPELICCQEKMASFSFLKDNPDE-CLYNVIETAISELKEDLDIIS
KYSE-AVNCSYALHLFSRELEELSEIKKLLKKSEYSLSTYIDFVPYIASINYGNTVTELE
HNYDQFSTLLQNIMSIPQKDLGKMAHIMKVMKTIEHMKIICAKNAKLSTSFLLCQMAHNR
RDAFQ-LKKEEKMNIHAVKPEENTNKSSLSM-KVPLISECIIKNFPNSSKKQPIHTDNCF
Y-LN------------------------------VTLNRTTRSHCKIENEIGSNSSYNLK
RNYV-SPKMVEMQS----SLLPLKTLQNACTSRSESNIDLTNSSSGTSEHITRQHKNL-N
TIKK--RKMSFSVAETKSNENKHASFAPCDQRNIDD-TFGEDHNI---------TDPTQK
SCLSNINPGTDDCLVPNA-TMFSKPVFHFLREIHTNLEMN-DTVLECQDNEMLNSSIKNS
T---CISSPEPTHIQGKISILQENKKHPAKTESEEKYMKNTLKPSMI-PFGQTGILTLDA
NQRAEYSLSEQQ---DENPKVLNKKGATYWNELPQSTCNPIYNSSEHSFGATSYPYYSWC
VYHYSS--SNGNAITHTYQGIESYEVYP---PPSGILTTVAS-----TVQTTHSNILYSQ
YFSCFAEQPQANAFMPADGYFQSQRPISYNFQQPIFSQYASHQPLPQAAYPYPPNSGVLQ
EVPWIYAPWQ-QEQFQPGH--

--------MATNKMEMKETAKQNTLWQMSST----SKPMLNTR-EVNPLKKFTIPKIRRT
AEKVYLSPCYTNSREYSFIYDTLNQCRLDVSCDLQS-LWQFGDTKLVHNEELEKNFTTKR
S

PF12509 // ENSGT00390000006260_0_Domain_0 (122, 279)

EMRESGRHCRELEEHFCFLALPQSDVAQIYQNGISTRA--STLKILGNPLLGIYMFRHV
DIALNYSHSHSIPVENILIFKV-LFGKVK------KIQPSVDKNKVSLDPSPNFDCHMSR
NAPSLKDTIE-LQAYSSAVYFYEYSVLSKPVDKPRQCL

ENSGT00390000006260_0_Linker_0_1 (279, 2115)

PYAVVTVKFIGSKVDNGYLMTS
LRFLSTGFPKRAERTCSLNNCTVAKRIGKGKDATVIFEHFKKPVDPF---VQENCLCNVL
NSEINPSNSHISNSYGNVQNG-NISVPETYNGQTEHNLAEIRDTSQVLAHDSDLSLTPND
AKGSV-NGDLLLNWTSLKNILSSLNAAFPLHNSTGSSTVTTSKFIKDPRLMRREESMGEQ
SNTAGLNEILQFEKSLDNVNSEIK---STPSNSASSSEVVPGDCAVLTNCLDAPCFTTCV
NDSQSWAHNTGSEDYDYVPHNKVTMAGQCKDQ---G-NFSFPISASNVVSEVENQNHSEE
KVQRAQQ---------------------------ESD---NVYKKEYNSHISQESQSSDL
KTIYQTGHQMS-TIFPLKKKVS-IDEYLQNTGKMKNF-TDLKDNS--KHDEKQTSWKEID
N-DFTNETKISPMDNYIVLHQE--YKESESHNSFKKSCDKILITQEL-EIPK-SSTSTIK
DKDELDHLALEWQ--IT-PSLESLSQKHPQHSVEYED-NIHTSLAISQKLMELKLGKIN-
ANCASIITEAFPKPKDIPQAKEILTDTVTSSYNRETAHDNSNCSITREHICVHRKNENEP
VSLENIQRDYKETAYVE---DRGQDHSLFCNSQL-NDIC---LNVNFK-EQRYNYKE---
---SQNEAKE-N-NASSVENNIENIYGDKKQDSHTN--ENFSY-IDEKED-KNYNNIEIL
SSEEFSATFNLICREK-YVSAATALLES--EEDTISAMKQKDTE-NTGRSVEHLASTA-F
PEI---ASSSVCVASNAAVQIASATMPVLS-ISNDEHQIYQSKETCSSESPDFGLLVKHR
VSDCEIDKDKNKSQESFHQSIN-EN---LVLQSIELESEI--EIEDCDDAFI--FQQDTH
SHENMLCEEFVTSYKALESRISWEGILALDNGEMEVLESTAGRENSDQLYSKESNYFYSS
TQNSETELPSPILLPDLQIRIT-NIFRPGFSPTVDSLALKDNFCTHVTEATKPEINKE--
----DGEIVGFDIYSQPSGENSDYPCEDKVDNI-RQESGPMSKS-EISLSFDLS-DNTDV
---NHMSK-NQNSESLFSEPSNVT-TIDNGSRCFFTKSK-TDYNDAKDKKEAESRISKRK
L-HTSSRDQNI-HKDLRQHKSYGRKRRLTSQDSSECFFSLSQGRIKTFSQSEEHIKSVLN
ILSGEASLCKSKCLSKKLDKAVIHLKKAHRKVHTSLQLITKIGEK-RRGPLPKSYAIICN
NF-WESCDLQGYSSVSQRKYYSTKHFLSKRKYDKRRKKRVPKADISKSLTYVSKHKSYK-
T------SGE--KKCLSRKSMASSVSKSHPT-IHVGEFCNQE-HPESQLSVSSTSQSTSQ
S-VYYNSSVSNPSLSEEHQPFSGK-TGCLFSPDHSDEKLIEKENQIDTKFLSSTSKYEKL
EKHSANHNVK---DATKENSCEANQVINESNSISLSCIKE-NINYNTGN-DYDATCIGCT
KVKTDVLISVLDSNVKHFLN-DLYQQENLILSDYKRNLEVKW-----TAPIERSKQSIIT
GNFLMDPLNLTLIASKK-YSIPQL-SASAVTDSEGESSKSYLDKQRILTIDSVAAST---
---TIPCCEQSCRGK--ELLKTEQCSSGNCLHTDGNETNVT-ENYELDVAS-VTEESRS-
-YGENI-------V-KLSSSDSSLLLKDNIKGSSSETCIVKKDTEDRITWKVKQVEKA-K
DSV----YKSSMTE-GSTVNTEYKNQKNQIS-EES-CLNEKIIKTNLIDCHLS-TKNTTT
E-SVSLKNTVSNPL

PF15326 // ENSGT00390000006260_0_Domain_1 (2115, 2382)

NKRE-K-AEIKV-SNDSQS---------------------------
-DLTLYSAIAYISK---PGILGVNHTPILPAHSETCKVTTLL-KKPASYMSELKEKRCPA
NHTALIANLSQILQRADEASSLQILQEETKVCLNILPLFVEAFERKQECSVEQILISREL
LVEQNLWNNCKHTLKPSAVDTLVELQMMMETIQFIENKKRHLEGEPTFRSLLWYDETLYA
ELLGKPHGFQQQSNFYPGFQGRLKYNAFCELQTYHDQLVEL

ENSGT00390000006260_0_Linker_1_2 (2382, 2589)

LEETKREKNSYYAFLKYKR
QVNECEAIMEHCSDCFDFSLSVPFTCGVNFGDSLEDLEILRKSTLKLISACG-DSPKVHS
YPGKQDHLWIIIEMISSKINFIKNNKAVHIKISLYGLEHILFDAAKNLVWKEETQSFSKK
YSQKEDKERLLRVNKCAFSKLQKIYDTLSKDLNSEP-ISLVGLEEDTIIASRKSDHPINK
ATISIENS

PF15326 // ENSGT00390000006260_0_Domain_2 (2589, 2722)

KFSS---SLLAHPGIYCISEILDQAEIADLKKLQDLTLRCTDHLEILKKYFQ
MLQDDNMDNIFITEENVLDMVKNHSHEAILLKPEAIEMYIEIVMVSETIHFLKNSIAKKL
DKQRFRGMLWFDLSLIPELVQCQEKMTSFSFLKDNSTDVCLWKVVETAIFKLKKDLDIIY
KYDE-VVNRSYAIHLLSRELQELSEIKKLLKNSKYFIPTYIDFVPYITSINYGSTLMELE
YNYNQFSTLLKNVMSAPRKDLGKMAHIMKVMKTIEHMKIICAKNAELTISFFLCQMLYNG
RKILQ-LKRKEKMNIHVVKPGENNNKFSISM-MVPPISECINKNISNSSKKRPSTVDTCE
D-SQEQQKNTTISSCKKLKVDMKDVTKINRENATFKHPRTTGSHPQSENKIVSSSSNNLK
RNHL-TSKKVEMQRSLPGSLSPLENPKDTCTSKSESKIDLT-VSSDAPDHFTGQQENL-N
SMRK--GNVNFNAAETKSDEKDCTAFAICDQKSAHG-TFSPDREILLQKFLKNSPDPTQK
SCLSDINPGTDVSLVPDA-SVLSKPIFCFVKDTHTDLEMN-DTVFELQDNDIVNSSIKNS
S---CVTSPEPICIQNKIPTLQINKLQPAETESEDKYMKNTLNPNTVHTFGASGHITLNV
NQGAEYSLSEQQ--NDKNSKLLTQNAATYWSELPQSACTPAYNSSEHLFG-TSCPYSAWC
VYHYSN--GN--GITQTYQGITSYELQS---PPSGLLTTVASGQGAQRAQGAHSNLLYSQ
YFTYFTGEPQANGFVPVNGYFQSQIPA-YNFQQSVFSQYASHQPLPQTTYRYLPNRDVPP
EVPWVYAPWH-QESFHPQH--

--------MATNKMEMKETAKENTLWQMSST----NEPLLNTG-EVNPLKKFTIPKIKRK
AGKVYLSPCCTNSREYSFIHDTLNQHRLDVSCNLQS-LWQFGDTKLIHNEELEKNFTAKR
S

PF12509 // ENSGT00390000006260_0_Domain_0 (122, 279)

EMRESGRHCRELEEHFCFLALPQSDVAEIYQNGISTRA--STLKILGNPLLGIYMFRHV
DIALNYSHSRSITVESILIFKV-LFGKVK------KIQPSVDKNKVSLDPSPNFDCHMSR
NAPSLKDTIE-VQAYGSTVYFYEYSVLSKPVDKPRQCL

ENSGT00390000006260_0_Linker_0_1 (279, 2115)

PYAVVTVKFIGSKADNGHLMTS
LRFLSTGFPKRAERTCSLDNCTVAKRIGKGKDATVIFEHFKKPVDPV---VQENCLYSVP
NSEINHSNSNISNSYGNVQNG-NISIPETYSGQTEHNLAEIRDTSQVLSHDADLSLTPSD
AKASV-NGDFVLNWTSLKNILSGLNATFPLHNNTGSSTVTTSKFLKDPRLMKREESTREQ
SNSAGLNEILQFEKSLDYVNSEIN-LSSTQSNSTSSSEVVPGDRAVFTNYLDAPCFNISV
DDSQSWAHNIDSEDYDCIPPDKVTMAGQCKDQ---G-NFSFPISVSNAVSEVKNQNHSEE
KAQRAQQ---------------------------ESV---NAYTKEYNSHISQELQSSNL
KTTYQTGYQMS-TIFPLQEKVS-IDEYLQNIGKVKNF-TDLEDDS--KHEEKQTSRKKIE
N-DFTNETKMSPIDNYIVLHQE--YKESESHNYFVKSCDKTLITQEL-EIPE-SSTSTIK
DKDELDRPALKWQ--VT-PSLESPSQKYPQHFVENED-NIHTDLAIAQKLMELKLGKIN-
QNCASIITEAFQKPKEVPQAKETLIDTVISSYNIETAHDDSNCNITREHVCIYRKNENEP
VSLENSQRDYKETAYVE---DKGQDHSLFCNSQLNNNIC---LNVNFK-EQRDNYKE---
---NQNEAKE-N-NASSEENNLENIHGDKKRGSHTN--ENFSI-IDEKEE-DKNYNIEIL
SSEEFSTTFNLICREK-YVSAETAFLES--EEDTISAMKQKDTE-NTGRSIEHLASTT-F
PEI---ASSSVCVASNAAVQIASATSPALS-TDNEDDQIYQFKETCSSESPDFGLLVKHR
VSGCEIDMDKNKLQESFHQSIN-EN---LVLQSIELESEIEIELEDCDDAFV--FQLGTH
SHENVLCEEFVTSYKALKSRITWEGLLALDNGEIEVLESTTGRENSDQHYSKASNYFYSS
AQNNETELPSPILLPDLQIRITNNIFRPGFSPTADSLALKDNFCTHIINATKLEINKE--
----DEETLGFGIYSQPSGENTDYPCEDKVGNI-RQESGLVSKA-EIALSFDLS-NNTDV
---NHMSE-NQNSESLFTEPSNVT-AIDDGSRSFSTKSK-TAYNDTKNKKEVESRSNKRK
L-DTSSRDQNISHKDLRRHEICGRKRRRTSQDSSECFSSLSQERIKTFSQSEKHIKSVLD
ILRNEASLCKSKRLSRKLDKAVIHLKKAHRRVHTSLQLMVKVGEK-GRGPLPKSYAIICN
NF-WESCDLQGCSSVSQRRYYSTKHFLSKRKYDKQRKKRALKADTSKSLTHVSKYKSYK-
T------SRG--KKCLSRKSMASSVSKSHPI-IHMGEFSNQE-HPESQLPVSSTSQITSQ
S-VYYNSSVSNPSLSEERQLFSGK-TRCLFSPNHSDEKLIEKENQIDTEFLSSIGKYEKL
ENHSANH--K---DATKENSCEINEVINESNSISSSCIKENNIDYSTGN-NYDATCMDHT
KVKTDVLISVLDSNMEHFLNVDLYQQNNLILSDCKRNLEVNFPIEKCTVPIERSKQNIIT
GNFLMDPLNRTLIASKK-YSVPQLLSAAAVTDSEGESSKSYLDKQRILTIDSFAAST---
---TVSNCEQSCRGK--ELLKTEQCSSGNCLHTNGSETNVT-ENYELDVTS-VTEESKS-
-YGENV-------V-KLSSSDSSLLLKDNVKGSSSETCIVKKDTEDRIMQKVKQAEKA-K
GSV----YK-SMTE-GSTVKTEYKNQKNQIS-EE--SLNEKMIKTNLIDSHLS-SESTTT
E-SISLKNTVSNPL

PF15326 // ENSGT00390000006260_0_Domain_1 (2115, 2382)

NKRE-KKGEIKV-SNISQS---------------------------
-DLTLHSEIACISK---PEILGVNHMPVLPAHSETCKVTTFL-KKPTSYVSEFKDKHSSA
NHTALIAQLSQILQRADEASSLQILQEETKVCLNILPLFVEAFERKQECSVEQILISREL
LVDQNLWNNWKHTLKPCAVDTLVELQMMMETIQFIENKKRRLEGKPTFRSLLWYDETLYA
ELLGKPRGFQQQSNFYPGFQGRLKYDAFCELQTYHDQLVEL

ENSGT00390000006260_0_Linker_1_2 (2382, 2577)

LEETKREKNSYYAFLKYKR
QVNECEAIMKHCSDCFDFSLSVPFTCGVNFGDSLEDLEILRRSTLKLISVHG-DSPKVHS
YPGKQDHLWIIIEIISSKVNFIKNNEVVCIKISLYGLEHIFFDAAKNLVWKERGQSFSKN
-SQKKDEERLLTVNKYAFSKLQKIYDTLSKDLNNEQ-ISSIGLEDTI-IAS--RNH

PF15326 // ENSGT00390000006260_0_Domain_2 (2577, 2722)

PINK
ATISTENCKFNS---TLLAHPDICCISEILDQAEFADLKKLQDLTLSCTDHLEILKKYFQ
MLQDDNIDNIFITEENVLDTVKNHSHAAVILKPEAIEMYIEIVMVSETIHFLKNSIAKKL
EKQRFRGMLWFDLSLLPELVQCQEKMASFSFLKEYSTDVCLWKVIETAISELKKDLDIIY
KCNE-AVNCSYALHLLSRELQELSEIKKLLRKSEYPTSTYIEFVPYIASINYGSTITELE
YNYNQFSTLLKNIMSAPRRDLGKMAHIMKVLKTIEHMKIICAKNAELTISFILYQMLWNR
RKILQ-LKRKENLNIHVVKPEENINKSSISM-MIPPISECLIKNISKSSKKPPSSADKCE
D-SQEQQKN-TVSCCKKLKVDMKDVTKISREKATFKHPRTTGSQPESEKKIVSSSSNNLK
RNHL-TPKKVEMQRSLPGSL--LENPKDTCTSKSEIKIDLT-VS----EHFTGQQENL-T
NIKK--TNVNFSAAETKSDNKDCAAFAICDQKSVHG-TFSPDHETVMKKFLKNSPDPTQK
SCLSDMNPGTDVSLVPDT-SVLSKSIICFEKDGHIDLEMN-DTVFKLQDNDIVNSSIKNS
T---CMTSPEPIFIQNKIPTLQINKLQPAETESEDKYMKDTLNPNIVHTFGASGPITLNV
NQTAEYSFSEQQ--NDENSKVLPQNAATYWNELPQSACTPVYNSSENLFG-TSYPYYSWY
VYHYSS--SNGNAITQTYQEITSYEVQP---PSSGLLTTVAS-----TTQSTHSNLLSSQ
YFTYFAREPQANNFVPVNGYCQSQIPAADNFQQPIFSQYASHQPLPQATYPYLPNLDVPP
EVPWTYAPWH-QQSFHPGH--

-------------MEMKDIAKHKTLWKMNST----SEPLLLAGVEVNPLKKFTIPKIRRA
AGKAYLSPCCTNTREYSFIHDTLNQCRLDVGCDLQS-SWQFGDTKLVHNEDLEKKFTSKR
S

PF12509 // ENSGT00390000006260_0_Domain_0 (122, 279)

EMRESGRHGRELEEHFCFLALTQNDVAEIYQNGISTRA--STFKILGNPLLGIYVFRHV
DIALNYAHSKSITVESIIIFKV-LFGKVK------KIRPSLDKNKVSLDPSPNFDCHMSR
SIPSLKDAIE-LQAYNSAVYFYEYNVLSKPVDKPRHCL

ENSGT00390000006260_0_Linker_0_1 (279, 2114)

PYATVTVKFIGQKVDSGHLITS
LRFLSTGFPKRAERTCSLNNCTVAKRIGKGKDATVIFEHFRKPVDPF---VQENCSCGAL
NSEINPSNTNISNSYGNVKNG-NISIYETYGGQMEHNLAECGDTS--CIYDSGLSFIPSD
TRESV-NGDPMLNLAHLKNTLSGLSAAFPLHNNTGSSTVITSKLIKDPRLMRREESIGKH
NNITDLNEILPLEKSLDFVNSEIN-LSSMPNNSASSSEVVPGDDSVLTNCLDAPSFKISF
DGSQSQAHNLDVNNYDYTIPSKITPAGQCKGQ---D-NFSFPMCLPNVVSEVENQKHNEE
EAQRSELRSNIPLLIEENSEAHN---------SYESV---NICTKGHSNHISLESWSSNL
ETVSQTGQQMS-TAFPLQRKES-IHEYTQNIGEMRDF-TGPEDNS--KHGEKQVLWKEID
---FTKEAKVSPVDNYISLYQE--YKEDESLDSYGKNCDQILIAQEL-EIQK-SSTSTTK
DEYELDHLNLELQ------RVESLSQKHPQLSLDYED-NIHTSFAISQKLMELKLGKPN-
QNCVSIVTDAFQEAKDIPQVKELPIDAIISSHDIKPTHDNSDYKITGE-VCVHGRKENDP
VSLENIQRDCGETFQID------EGHTLFCNAELHSDTH---LNIDFR-EQGDNDKE---
---NENEAKEED-IALSTE-SRENIYGEEKQGFHTN--QSYTN-IDERRENKNYNNVEIL
SSEECC-TFNLSSGER-HVSTEATLLEN---EDTMTATQQKDAP-NTGRTVEHLAYTA-F
PKV---EGSSEHEASSTAVQTAGATVPTLG-TNREDHQRYQIKETCSSESLDFGLLVKHR
VSDCEMDMDNNKLHDSFHQSVS-DT---SVLQSFKLENKIEVGLEQCDDAFL--IQQH--
SHRNDPCEEFRAIYETLKSRIDWEGLFGSNNGEREVSKSSRRNENSDQHYPKKSICFYPS
TEKN--KELNPILLPDLQIRIT-NTFMPGFNPTFESLALKDNFCKYITKTTGPEINE---
----EGKVSGFEMYSHCSGENSGYPCEDEFGNR-RQESGLVNKS-EIALSLDVS-NNTQV
---NHVSE-KQNSGPLPTEPSNVT-ALNNESRCSLTGSK-TDCNDITSKKDTQSRISKRK
R-RMPFRDQNTPHKDLRRREIYGKKRRLTSLDSSEHFSSLSQGRIKTFSKSEKHIRSVLD
ILNSEASLCKSKRLSRRLDRAVLHLKKAHRRVHTSLQLIAKVGEK-RKGPLPKSYAIICN
NF-WESCDLQGYSSVSERRYYSTKHFLSKRKYGKPGEKRALGFEVDKSLTHVSKPKSYK-
A------SRARIAECISKRNMASSVSRSHTT-IHVREFCDLE-YPESQLALCSTSQSASH
S-AYNKSRVRN-RTSSELQLFSGK-TGCLFSPACPDAKITEKENQVGIKFLSNINKYENP
ENHSAHNNIK---DA--ENNSETNKVINKSNSVSLSCIKEDKVSFSTDT-SYNATCITHT
KVKTDIVISVLESDIKHLLNVDVCTPDNLILSDCKGNLEVNLPVEERTAANQSSKPGTVP
ENFIKDPLNLTLITHKNSDSIPQLLSTTAVTDSEGESSESYLDKQRVFAVDSFTTST---
---SVPHCQPGCGGK--ELLKTEQCSSSNRFHIDGNESHVL-EDSELGLRL-VTEESKS-
-CRKNT-------MKELFSNDSYLLLKDNMKGS-SKKCMANKDIWDRKMWKVKQAEKA-R
DSL----HKKSMTE-GCTVKTQFKNQKNKIL-EESSYLSKKTIKNNLIDSHLN-VENITE
A--VALNNPVSNH

PF15326 // ENSGT00390000006260_0_Domain_1 (2114, 2382)

LNKRE-KEGGVKV-SNDPQS---------------------------
-DSALHSEIACNSK---PGIIGMNHIPVLHTNSQTSEVSTPE-KKPASYMSGLKEKHCSA
NHSALTARLAQILRRADETSSLQILLEETKACQSILPLFVEAFERNQECSLEQILISREL
LVEQNLWNNCRHKLKPCAVDSLVELQMMMETMQFIENKKRLLGGEPTYRSLLWYDETLYS
ELLGRPRGFQQQSSFYPAFQGRLKYNAFCELQNYHDQLIEL

ENSGT00390000006260_0_Linker_1_2 (2382, 2602)

FEETKRENNSYYAFLKYKR
QINECEAVMKRCSDCFDFSLSVPFTCGVNFGDSLGDLETLRKSTLKLIGMYG-DSPKVDS
YPGKQDHLWIIIEMITSKVNFIKSSEAISIKISLYGLEHIFFDAAKSLIWKEKRESFRKI
YSGEKNREMLLKMNQCAFSKLKKIYDTLSKDLSSEQ-ISNTALEN-MEIASRKSDDLINK
APVTLENCGFNS---TLLSHP

PF15326 // ENSGT00390000006260_0_Domain_2 (2602, 2722)

DICCISEILDQAEFADSKKLQDLTLRCTEHLEILKKYFQ
MLQEENIDNIFITEENVLDMVKNHNHGAIILKPAAIETYIEIVMLSETIHFLKNSMAKKL
DKQRFRGMLWFDLSLLPELVHCQEKMASFSFLKDNSTD-CLWKVIETAISELKKDLDIIY
KYSE-AVNCSYALHLLSRELQELTEIQKLLKKSQYSVSTYIDFVPCIASINYGSTMTELE
YSHNQFSALLKNIMAAPRKDFGKMAHIMKVMKTIEHMKIICTKNAELTISFILCQMLHNR
KKTSQ-LQGKEKTNVHV-KPRKDSNKSSIYM-KVPSISECIMKTVSNSSEKRSITVDKCG
D-PQKRQKNTTVSSCKKQKVDIKDVTKINREKATFKDSRTTRSHLESESEIGPSSSDNLK
RNHV-SPKKAEMERSLLGSLLPLKNLKDTCISKSEGKIDLTNISSHTSEDFTGQQGNL-S
SMKK--RDVNFSVAETKSDKKDCC-FVSCEQKSVDGI-----------------------
-----------------------------FRDFPANLETS-NTVFELQDHEILNSSIKNS
A---CTNPSESKFIQDKFPVLQVNKTQPAKTELKGKCMKDTFSPNTI-PVGASGNITLSV
NQTTEHSFSEQQ--NNENSKALTQNAAACWNELPQSACTPIYNSSQHPFG-TSYPYYAWC
VYHYSN--SSGSSITQTYHGITSYEVQP---PPSAMLTAIAS-----TVQNAHSNLLYSQ
YSGYFSGEPQANDLVPVNGHFQSQMPVSYHFQQPIFSQYAPHQAFPQAAYPYPPDSGVLP
QVPWTYVPWQ-QEPFQPGQ--

--------MATNKMEMKEIAKHKTLWKMNST----GEPLLVTGVEVNPLKKFTIPKIRRT
AGKVYLSSCCTNTREYSFIHDTLTQCQLDLGCDLQS-SWRFGDTKL

PF12509 // ENSGT00390000006260_0_Domain_0 (107, 279)

VHNEELEKNFTSKR
SEMRESGRHGRELEEHFCFLALPQNDVAEIYQNGISTRT--STLKILGNPLLGIYVFRHV
DVALNYARSRSITVESIIIFKV-LFGKVK------KIQPSVDKNKVSLDPSPNFDCHMSR
SIPSLKDTIE-LQAYNSAVYFYEYNVLSKPVDKPRQCLPYAILTVKFIGQKVDNGHLMTS
LRFLSTGFPKRAERTCSLNNCTVAKRIGKGKDATVIFEHFRKPVDPF---VQENCSCSAV
NSEINPSNENISNSYGNVQNG-NISIHETYSGQMEHNLAECRDTSQVHIYDSGLSFFPSD
TRESV-NGDFMLNLTQLKNVLSGLSAAFPLHNNIGSSTVITSKLIKDPRLMKREESIGKH
NNITGLNKILPLEKSLDF-NSEEH-LSSTQNNSAFSSEVVPGDRSILTNCLDAPCFKVSF
DDSQSQAQNWGSKNYDYTTPGKITMARQCKGQ---D-NFSFPMCLPNAVSEVENQKHNEE
KVQRSQQRGNISLLIEEEGEPRN---------SHESV---NTCTEGYSSHISQKSWSSNL
ETVYQTGQQMS-TVFPLQKKES-IRGYLQNIGKMRDF-TSPEDNS--EHGEKQILWKEND
---FTNEAKIRPVDNYISLHQE--YKENESLCSFRKNCDQIPITQEL-EIPK-SSAFTTK
DKYDLDHLALELESNLT-PRVESLSQKHSQPSLEYED-NIHTSFAISQKLMELKLEKPN-
QNSVNIMTNALQEAKDIPQDKELPNDRITSSHDIKTTHDNSDCSIAGEHTCV---HENDP
VSLENMQKDCRETFQNA---NKGQGHTLCCNAELYSDIH---LNTDFK-EQGDNDKE---
---NENEAKEED-TALSTENNRLDIYEDEKQGFRTD--KNYAI-IDERRENENYNNVEIL
SSEEFC-TFNLTWGKR-HVSTETTFLES---EDTITAIKQKDSQ-NTSRSVEHLASTT-L
PKI---AASSVHVASNAAVQITGDMVPTLG-TNHEDHQRYQIKETCSSESLDVGLLVKHK
VSDCEMDVDNNKFHDSFFQSVS-DS---RILQSCELENKIELGSELCDDVFL--IQQNTP
SHRNALYEEFGASYEALKSRIDWEGLLESNNGEREVLKSSRGRENNDQHYSEESNSSYSS
TQKD-KELFNPILLPDLQVKIT-NVFMPGFTPTFESPALEDNFCKNITKTKEPEMDE---
----EEKLPGFEIYSQCSGEYSHHPCENESGNT-SQESGLVSKS-EISLSLDAN-HNTQG
---NHASE-KQNSGPLLTEPSNVT-ALSNERSCSLTNSK-TDCNDTRSKKDTGSRISKRK
P-NTPFRNENTAHKDLKHHEIYGKKRKLTDQDSSECFSSLSQGRIKTFSKSEKHIRSVLD
ILNSEASLCKSKRLSRKLDRAVLHLKKAHRRVHTSLQLIAKVGEK-RKGPLPKSYAIICN
NF-WESCDLQGYSSVSERRYYSTKHFLSKRKYDRPGEKRALGFEVGKSLTHVSKHKSFK-
T------SRERITECVSKKNVASSVSRSHTT-IHVREFCEKE-YPESQLALCSTPQSTSY
S-AYNKSSMKS-LRSSELQPFSGK-PGFLFSPSCPDKL--TKKNKIDTTFLSNISKYEKP
EYHSANNKIK---DLMKESNSETNKSINKSNSVSLNCIKENNVSFSRDK-NYDATCITHT
KVKTDIVISVLESNVKHFLNVDIYKPDNLILSGYKRNLEVTFPIEEWTAPTQSSKPGIIA
GDMLMDPLNPTLVTHKKYNSVPQLLTTTPVTASEGESSESYLDRQRTFSVDSFATST---
---NVPHCQPRCGGK--ECLKTEQWSSSNCFHIDENDSGVL-ENSELGLKL-VTEESKS-
-CRKKT-------MKKLFSNDSSLLLKGNMKCSSSKKCMAKTDIQDRKMWKVKHAEKA-K
DSL----HIKTMTE-GFTA-TKYKNQKNKIL-EDSSYLCEKRIKNNVIDSHQI-FEDITE
V--VSLNNTVSNHLSKRE-KEGEVKV-SNNSQS---------------------------
-DSALHSEIACNSK---PHITGMNHRPVLHMHSQTSESS-TE-KKPASNVNGLKEKYCSA
DHSSLIPRLAQILRRADETSSFQILQEETKACQSILPLFVEAFERKQECSHEQILISREL
LVEQNLWNNCKHKLKPCAIDSLVELQMMLETIQFIENKKRLLGGEPTFRSLLWYDETLYG
ELLGRPRGFQQQSNFYPAFQGRLKYNAFCELQNYHDQLIELFEETKRENNSYYAFLKYKR
QINECEAIMKHCSDCFDFSLSVPFTCGVNFGDSLGDLETLRKSTLKLIGMYG-DSPKVDS
YPGKQDHLWIIIEMISSKVNFIKNNEAVSIKISLYGLEHIFFDAAKSLVWKERRQSFSKK
YSGKKDKEMLLKMNQYAFSKLKNIYDTLSKDLSSEQ-ISNIGLEN-TEIASRKSDDLINK
ATVNMEDCRFNS---TLLSHPDICCVSEILDQAGFADSEKLEELTLRCIGHLEILKKYFQ
MLQEENIDHIFITEENVLDMVKNHNHGAIILKPAAIETYIEIVMLSETVHFLKNTMAKKL
DKQRFRGMLWFDLSLLPELVCCQEKMAPFSFLKDNSTD-CLWNVIETAISELKKDLDIIY
KYSE-GINCSYALHLLSRELAELSEIKKLLEMSKYSVSTYIDFVPYIASINYGSTMTELE
YNYNQFSTLLKNIMAAPQKDLGKMAHIMKVMKTIEHMKIICAKNAELTISFILCQMLHNR
KKTLQ-LKRKEKMNMHV-KPRKSISKSSTFM-KVPSISECIMKNVSNSSKKRSITVDKCE
D-SQEQEKNSTVSSCKKQKVDMKDVTEINREEATFKHPRTMRSHPESPREIGATSSDNLK
RNHV-SQKKIEVERSLPDSLLPSKNLKDTCTSKPEDRIDLTNISSNTSKDLTGQQGNL-S
SMKK--SNANFSAPETKTDKKACSSFTICEQRSVDG-VFPKDCKMPSQRFL----NPAEK
FCPSNIKPGTE----PDG-SVLSKPVFRFVRDIPANIETN-DTVFELQDYEILNSSIKNS
A---CTNSSESRFNQDKSPILQVNKTQPEKTELKEKYM-DTLSPSSI-PLGASEDITLNV
NQTAEYSFSEQQ--NNENPKVLTQNAAAYWNELPQSACAPICSSSAYAFG-TSYPYYAWC
VYHYSS--SGSSSLTQTYRGIT-YEVQP---PPPGMLTAIAS-----TVQSSHSNLLYSQ
YFGYFAGERQASDFLPVNGYFQSQMPVPYNFQQPVFSQYAPHQSFPQPVYPYPPDSGVLP
EVPWTYVPWQ-QEPFQPGH--

--------MATNKMEMKETAKQNTLWQMSST----SEPMLNTR-EVNPLKKFTIPKIRRT
AEKVYLSPCYTNSREYSFIHDTLNQCRLDVSCDLQS-LWQFGDTKLVHNEELEKNFTTKR
S

PF12509 // ENSGT00390000006260_0_Domain_0 (122, 279)

EMRESGRHCRELEEHFCFLALPQSDVAQIYQNGISTRA--STLKILGNPLLGIYMFRHV
DIALNYSHSRSITVESILIFKV-LFGKVK------KIQPSVDKNKVSLDPSPNFDCHMSR
NAPSLKDTIE-LQAYSSAVYFYEYSVLSKPVDKPRQCL

ENSGT00390000006260_0_Linker_0_1 (279, 2115)

PYAVVTVKFLGSKVDNGYLMTS
LRFLSTGFPKRAERTCSLNNCTVAKRIGKGKDATVIFEHFKKPVDPF---IQENCLCNVL
NSEINPSNSHISNSYGNVQNG-NISIPETYNGQAEHNLAEIRDTSQVLAHDSDLPLMPSD
AKESV-NGDLLLNWTSLKNILSSLNAAFPLPNNTGSSTVTTSKFIKDPRLMRREESMGEK
SNTAGLNEILQFEKSLDNVNSEIK---STPSNSASSSEVVPGDCAVLTNCLDAPCFKTCV
NDSQSWAHNTGSEDYDCVPPNKVTMAGQCKDQ---G-NFSFPISVSNVVSEVENQNHSEE
KVQRAQQ---------------------------ELG---NAYKKEYNSRISQESQSSDL
KTIYQTGHQMS-TIFPLKKKVS-IDEYLQNTGKMKNF-TDLKDNS--KHEEKQTSWKEID
N-DFTNETKISPMDNYIVLHQE--YKESESHNSFEKSCGKILITQEL-EIPK-SSTSTIK
DKDELDHLALEWQ--IT-PSLESLSQKHPQHSVEYED-NIHTSLAISQKLMELKLGKIN-
ANCASIITEAFPKPKDIPKAKEMLIDTVISSYNIETAHDNSNCSITRKHICVHRKNENEP
VSLEDIQRDYKESAYVE---DRGQDHSLFCNSQL-NDIC---LNVNFK-EQRDNYKE---
---SQNEAKE-N-NASSVENNIENIYGDKKQDSHTN--ENFSY-IDEKEE-KNYNNIEIL
SSEEFSATFNLICREK-YVSAATALLES--EEDTISAMKQKDTE-NTGRSVEHLASTA-F
PEI---ASSSVCVASNAAVQIASATMPVLS-ISNDEHQIYQFKETCSSESPDFGLLVKHR
VSDCEIDKDKNKSQESFHQSIN-EN---LVLQSIELESEIEIELEDCDDAFI--FQQDTH
SHENMLCEEFVTSYKALKSRISWEGILALDNGEMEVLESTAGRENSDQHYSKESNYFYSS
TQSSETELPSPILLPDLQIRIT-NIFRPGFSPTVDSLALKDNFCTHVTEATKPEINKE--
----DGEILGFDIYSQPSGENSDYPCEDKVDNI-RQESGPMTKS-EISLSFDLS-HNTDV
---NHRSK-NQNSESLSSEPSNVT-TVDNGSTCFFTKSK-TDYNDTKNKKEVESRISKRK
L-HTSSRDQNI-HKDLRQHKIYGRKRRLTSQDSSECFSSLSQGRIKTFSQSEKHIKSVLN
ILSGEASLCKSKCLSKKLDKAVTHLKKAHRRVHTSLQLITKVGEK-RKGPLPKSYAIICN
NF-WESCDLQDYSSVSRRKYYSTKHFLSKRKYDKRRKKRAPKADISKSLTYVSKHKSYN-
T------SGE--KQCLSRKSMASGVSKSHPT-IHVGEFHNQE-HPESQLPISSTSQSTSQ
S-VYYNSSVSNPSLSEEHQPFSGK-TGCLFSPDHSDEKLIEKENQIDTKFLSSTSKYEKL
EKHSANHNVK---DTTKENSCEANQVINESNSISLSCIKE-NINYSTGN-DYDATCIGCT
KVKTDVLISVLDSNVKHFLN-DLYQQENLTLSDYKRNLEVKW-----TAPIERCKQSIIT
GNFLMDPLNLTLIASKK-YSIPQL-SASAVTDSEGESSKSYLDKQRILTIDSFAAST---
---TIPCREQSCRGK--ELLKTEQCSSGNCLHTDGNETNVT-ENYELDIAS-VTEESRS-
-YGENI-------V-KLSSSDSSLLLKDNVKGSSSETCIAKKDTEDRIMWKVKQVEKA-K
DSV----YKSSMTE-GSAVNTEYKNQNNQIS-EES-CLNEKIIKTNLIDSHLS-TKNNTT
E-SVSLKNTVSNPL

PF15326 // ENSGT00390000006260_0_Domain_1 (2115, 2382)

NKRE-K-AEIKV-TNDSQS---------------------------
-DLTLHSEIAYISK---PGILGVNHTPILPAHSETCKVTTLL-KKPASYMSELKEKHCSA
NHTAFIANLSQILQRADEASSLQILQEETKVCLNILPLFVEAFERKQECSVEQILISREL
LVDQNLWNNCKHTLKPSAVDTLVELQMMMETIQFIENKKRRLEGEPTFRSLLWYDETLYA
ELLGKPRGFQQQSNFYPGFQGRLKYNAFCELQTYHDQLVEL

ENSGT00390000006260_0_Linker_1_2 (2382, 2600)

LEETKREKNSYYVFLKYKR
QVNECEAIMEHCSDCFDFSLSVPFTCGVNFGDNLEDLEILRKSTLKLISACE-DSPKVHS
YPGKQDHLWIIIEMISSKVNFIKNNEAVCIKISLYGLEHIFFDAAKNLVWKEKTQSFSKK
YSQKEDKERLLRVNKCAFSKLQKIYDTLSKDLNNEP-ISPVGLEEDTIIASRKSDHPINK
ATIGIENSKFSS---SLLT

PF15326 // ENSGT00390000006260_0_Domain_2 (2600, 2722)

HPDIYCISEILDQAEFADLKKLQDLTLRCTDHLEILKKYFQ
MLQDDNMDNIFITEENVLDVVKNHSHEAILLKPEAIEMYIEIVMVSETIHFLKNSIAKKL
DKQRFRGMLWFDLSLLPELVQCQEKMTSFSFLKDNSTDVCLWKVIESAISELKKDLDIIY
KYDE-AVNRSYAIHLLSRELQELSEIKKLLKNSKYFISTYIDFVPYITSINYGSTMMELE
YNYNQFSTLLKNVMSAPRKDLGKMAHIMKVMKTIEHMKIICAKNAELTISFFLCQMLYNG
RKILQ-LKRKEKMNIHVVKPGGNNNKFGISM-MVPPISECINKNISNSSKKRPSTVDKCE
D-SQEQQKNTTISSCKKLKVDMKGVTKINRENATFKHPRTTGSHPQSENKIVSSSSNNLK
RNHL-TSKKVEMQRSLPGSLLPLENPKDTCTSKSESKIDLT-VSSDAPDHFTGKQENL-N
SMRK--RNVNFSAVETKSDEKDCAAFAICDQKSTHG-TFSPGHEILLQKCLKNSPDPSQN
SCLSDINPETDVSLVPDA-SVLSKPIFCLVKDIHTDLEMN-DTVFELQDDDTVNSSIKNS
S---CMTSPEPICIQNKIPALQINKLEPAETESEDKYMKNTLNPNTVHTFGASGHITLNV
NQGAEYSLSEQQ--NDKTSKVLMQNAATYWNELPQSACTPTYNSSEHLFG-TSYPYSAWC
VYHYSS--SNGNGITQTYQGITSYELQS---PSSGLLTTVASGQGAQCAQGAHSNLLYSQ
YFTYFAGEPQANGFVPVNGYFQSHIPA-YNFQQPVFSQYASHQPLPQTTYPYLPNRDVPP
EVPWVYAPWH-QESFHPQH--

-------------MEMKETAKQNTLWQMSST----SEPMLNTR-EVNPLKKFTIPKIRRT
AEKVYLSPCYTNSREYSFIHDTLNQCRLDVSCDLQS-LWQFGDTKLVHNEELEKNFTTKR
S

PF12509 // ENSGT00390000006260_0_Domain_0 (122, 279)

EMRESGRHCRELEEHFCFLALPQSDVAQIYQNGISTRA--STLKILGNPLLGIYMFRHV
DIALNYSHSRSITVESILIFKV-LFGKVK------KIQPSVDKNKVSLDPSPNFDCHMSR
NAPSLKDTIE-LQAYSSAVYFYEYSVLSKPVDKPRQCL

ENSGT00390000006260_0_Linker_0_1 (279, 2116)

PYAVVTVKFLGSKVDNGYLMTS
LRFLSTGFPKRAERTCSLNNCTVAKRIGKGKDATVIFEHFKKPVDPF---IQENCLCNIL
NSEINPSNSHISDSYGNVQNG-NISIPETYNGQAEHNLAEIRDTSQVLAHDSDLPLMPSD
AKESV-NGDLLLNWTSLKNILSSLNAAFPLPNNTGSSTVTTSKFIKDPRLMRREESMGEQ
SNTAGLNEILQFEKSLDNVNSEIK---STPSNSASSSEVVPGDCAVLTNCLDAPCFKTCV
NDSQSWAHNTGSEDYDCVPPNKVTMAGQCKDQ---G-NFSFPISVSNVVSEVENQNHSEE
KVQRAQQ---------------------------ELG---NAYKKEYNSRISQESQSSDL
KTIYQTGHQMS-TIFPLKKKVS-IDEYLQNTGKMKNF-TDLKDNS--KHEEKQTSWKEID
N-DFTNETKISPMDNYIVLHQE--YKESESHNSFEKSCGKILITQEL-EIPK-SSTSTIK
DKDELDHLALEWQ--IT-PSLESLSQKHPQHSVEYED-NIHTSLAISQKLMELKLGKIN-
ANCASIITKAFPKPKDIPEAKEMLIDTVISSYNIETAHDNSNCSITRKHICVHRKNENEP
VSLEDIQRDYKETAYVE---DRGQDHSLFCNSQL-NDIC---LNVNFK-EQRDNYKE---
---SQNEAKE-N-NASSVENNIENIYGDKKQDSHTN--ENFSY-IDEKEE-KNYNNIEIL
SSEEFSATFNLICREK-YVSAATALLES--EEDTISAMKQKDTE-NTGRSVEHLASTA-F
PEI---ASSSVCVASNAAVQIASATMPVLS-IRDDEHQIYQFKETCSSESPDFGLLVKHR
VSDCEIDKDKNKSQESFHQSIN-EN---LVLQSIELESEIEIELEDCDDAFI--FQQDTH
SHENMLCEEFVTSYKALKSRISWEGILALDNGEMEVLESTAGRENSDQHYSKESNYFYSS
TQSSETELPSPILLPDLQIRIT-NIFRPGFSPTVDSLALKDNFYTHVTEDTKPEINKE--
----DGEILGFDIYSQPSGENSDYPCEDKVDNI-RQESGPMSKS-EISLSFDLS-HNTDV
---NHRSK-NQNSESLSSEPSNVT-TVDNGSTCFFTKSK-TDYNDTKNKKEVESRISKRK
L-HTSSRDQNI-HKDLRQHKIYGRKRRLTSQDSSECFSSLSQGRIKTFSQSEKHIKSVLN
ILSGEASLCKSKCLSKKLDKAVTHLKKAHRRVHTSLQLITKVGEK-RKGPLPKSYAIICN
NF-WESCDLQDYSSVSRRKYYSTKHFLSKRKYDKRRKKRAPKADISKSLTYVSKHKSYN-
T------SGE--KQCLSRKSMASGVSKSHPT-IHVGEFHNQE-HPESQLPISSTSQSTSQ
S-VYYNSSVSNPSLSEEHQPFSGK-TGCLFSPDHSDEKLIEKENQIDTKFLSSTSKHEKL
EKHSANHNVK---DTTKENSCEANQVINESNSISLSCIKE-NINYSTGN-DYDATCIGCT
KVKTDVLISVLDSNVKHFLN-DLYQQENLTLSDYKRNLEVKW-----TAPIERCKQSIIT
GNFLMDPLNLTLIASKK-YSIPQL-SASAVTDSEGESSKSYLDKQRILTVDSFAAST---
---TIPCREQSCRGK--ELLKMEQCSSGNCLHTDGNETNVT-ENYELDIAS-VTEESRS-
-YGENI-------V-KLSSSDSSLLLKDNVKGSSSETCIAKKDTEDRIMWKVKQVEKA-K
DSV----YKSSMTE-GSAVNTEYKNQNNQIS-EEC-CLNEKIIKTNLIDSHLS-TKNNTT
E-SVSLKNTVSNPLN

PF15326 // ENSGT00390000006260_0_Domain_1 (2116, 2382)

KRE-K-AEIKV-TNDSQS---------------------------
-DLTLHSEIAYISK---PGILGVNHTPILPAHSETCKVTTLL-KKPASYMSELKEKHCSA
NHTAFIANLSQILQRADEASSLQILQEETKVCLNILPLFVEAFERKQECSVEQILISREL
LVDQNLWNNCKHTLKPSAVDTLVELQMMMETIQFIENKKRRLEGEPTFRSLLWYDETLYA
ELLGKPRGFQQQSNFYPGFQGRLKYNAFCELQTYHDQLVEL

ENSGT00390000006260_0_Linker_1_2 (2382, 2599)

LEETKREKNSYYVFLKYKR
QVNECEAIMEHCSDCFDFSLSVPFTCGVNFGDNLEDLEILRKSTLKLISACE-DSPKVHS
YPGKQDHLWIIIEMISSKVNFIKNNEAVCIKISLYGLEHIFFDAAKNLVWKEKTQSFSKK
YSQKEDKERLLRVNRCAFSKLQKIYDTLSKDLNNEP-ISPVGLEEDTIIASRKSDHPINK
PTIGIENSKFSS---SLL

PF15326 // ENSGT00390000006260_0_Domain_2 (2599, 2722)

THPDIYCISEILDQAEFADLKKLQDLTLRCTDHLEILKKYFQ
MLQDDNMDNIFITEENVLDVVKNHSHEAILLKPEAIEMYIEIVMVSETIHFLKNSIAKKL
DKQRFRGMLWFDLSLLPELVQCQEKMTSFSFLKDNSTDVCLWKVIESAISELKKDLDIIY
KYDE-AVNRSYAIHLLSRELQELSEIKKLLKNSKYFISTYIDFVPYITSINYGSTMMELE
YNYNQFSTLLKNVMSAPRKDLGKMAHIMKVMKTIEHMKIICAKNAELTISFFLCQMLYNG
RKILQ-LKTKEKMNIHVVKPGGNNNKFGISM-MVPPISECINKNISNSSKKRPSTVDKCE
D-SQEQQKNTTISSCKKLKVDMKGVTKINRENATFKHPRTTGSHPQSENKIVSSSSNNLK
RNHL-TSKKVEMQRSLPGSLLPLENPKDTCTSKLESKIDLT-VSSDAPDHFTGKQENL-N
SMRK--RNMNFSAVETKSDEKDCAAFAICDQKSTHG-TFSPGHEILLQKCLKNSPDPSQN
SCLSDINPETDVSLVPDA-SVLSKPIFCLVKDIHTDLEMN-DTVFELQDNDTVNSSIKNS
S---CVTSPEPICIQNKIPALQINKLQPAETESEDKYMKNTLNPNTVHTFGASGHITLNV
NQGAEYSLSEQQ--NDKTSKVLMQNAATYWNELPQSACTPTYNSSEHLFG-TSYPYSAWC
VYHYSS--SNGNGITQTYQGITSYELQS---PPSGLLTTVASGQGAQCAQGAHSNLLYSQ
YFTYFAGEPQANGFVPVNGYFQSQIPA-YNFQQPVFSQYASHQPLPQTTYPYLPNRDVPP
EVPWVYAPWH-QESFHPQH--

---------------------------MNST----NEPLLVTGVDISPLKNFTIPKIRRT
AGKVYLSPCCTNTREYSFIHDTLNQCRLDVSCDLQS-SWQFGDTKL

PF12509 // ENSGT00390000006260_0_Domain_0 (107, 279)

VHNEDLEKNFTSKR
SEMRESGRHGRELEEHFCFLALPQSDVAEIHQNGISTRA--STLKILGNPLLGIYMFRHV
DVALNYAHSRSITVESIIIFKV-LFGKVK------KIQPSVDKNKVSLDPSPNFDCHMSR
NIPSLKDTIE-LQAYSSAVYFYEYNVLSKPVDKPRQCLPYAIVTVKFIGQKVDNGHFMTS
LRFLSTGISKKAERTCSLNNCTVAKRIGKGKDATVIFEHFRKPVDPF---VRENCSCNAL
NSEINPPNSTISNSYGNVQSG-NISVLEAHNGQMEHSLAECRDTSQVHAQDSGLSFIPTD
SRESV-NGDLLLNLTHLKNILSNLSAAFPLHNNIDSSTVITSKLIKDPRLMRREGGMGKH
SNITGLNEILPFEKSLDVVNSGVN-LSSMPTNSASSSEVMPGDHALLTNCLDAPGFKISF
DDSQSQIHTMDFNSCNYTSSNIITMAGQREGQ---D-NFSFPVCLSSVISEVENYNHSEE
IAQRSQQRSNIPLLIEQNSEPHN---------SYEAV---NTSTEGYNGHISQESQSSNL
ETNYQTGHQMA-TVFQLQRKES-IHDYIQNIGKVRHF-TGPEDNL--KPGEKQNLWKEID
N-NFANETKISPVDSYISFHQE--CKKVESLDSSGKNSDQILITQEL-EIPK-FSTSTTK
DKYELDHLALELQNSLT-PKVEGISQKHRQHSLEYED-NIHTSFAISQKLMELKLEKPN-
QNCVSIMTDAFQEAKDNPQAKVLPNDTVVSS------QDNSNCNIYREHIRVNGRNQNDL
LSLENFQRDCEETPQID---DNSQDYTQFSNAQLNNDIH---LNIDFK-EQRDNDKE---
---NQNEAKEED-IASSTEDSIEKIYGGEKQSFHTN--ENFTD-IAERRENKNYNSVEIV
DSEGFSTTLNLTWGKK-YVSTETTLLER---EDTISAIKPKDTE-NTGRGVEHSASTT-F
PEI---SDSSVHVASNAAVQIASTVVPALG-TNHEYHQGYQFKETCSSVSTDFGLFIKHA
VSDCEMDVDKNKSHDPFHQSIS-DN---PILQSFELENEIEVGSEQCDDAFL--FQQDTP
SHGSVLCEEFRVSFEALKSRIDWEGLSRGSNGETEVLKSTTSRENSDQHYSEESNCFYST
TQKTKTGLFNPVLLPDLQVRIT-NMFMPGDSPTVESFALKDNFCKYITEATKPEINEE--
----EAKVPRFEICSQCSGENLDYPCEDECGNL-RHESGPVNKS-EISLSFDLS-HNTHA
---NHMSE-EQSSGPLLTEPANVT-TVNE-------------------------------
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--------LASNKMEMKETAKQNTLWQMNST----NEPLLNTG-EVNPLKKFTIPKIRRT
AGKVYLSPCCTNSREYSFIHDTLNQCRLDVSCDLQS-LWQFGDTKLIHNEELEKNFTAKR
S

PF12509 // ENSGT00390000006260_0_Domain_0 (122, 279)

EMRESGRHCRELEEHFCFLALRQSDVAEIYQNGISTRA--STLKILGNPLLGIYMFRHV
DIALNYSHSRSITVESILIFKV-LFGKVK------KIQPSMDKNKVSLDPSPNFDCHMSR
NAPSLKDTIQ-VQAYNSAVYFYEYSVLSKPVDKPRQCL

ENSGT00390000006260_0_Linker_0_1 (279, 2115)

PYAVVTVKFVGSKVDNGHLMTS
LRFLSTGFPKRAERTCSLNNCTVAKRIGKGKDATVIFEHFKKPVDPF---VQENCLYSAP
NSEINHSNSNISNSYGNVQNG-NISITETYSGQAEHNLAEIRDTSQVLAHDSDLSLIPSD
AKASG-NGDFVLNWTSLKNILSGLNAAFPLHNNTGSSTVTTSKFIKDPRLMRREERMGEQ
SNSAGSNEILQFEKSLDYVNSEIN-LSSTQSNSASSSEVVPGDRAVFTNCLDAPCFNISV
DDSQSWAHNIGSEDYDCRPPDKVTTAGQCKDQ---G-NFSFPISMSNVVSEVKNQNHSEE
KAQRAQQ---------------------------ESA---NAYTKEDNSHISQESQSSNL
KTIHQTGYQMS-TIFPLQKKVI-IDEYLQNTGKMKNF-TDLEDNS--KHEEKQTSRKKIE
N-DVTNETKISPIDNYIVLHQE--YKDSESHNYFGKSCDKILITQEL-EIPK-SSTSTIK
DKDELDHPALKWQ--VT-PSLESLSQKYPQHFVENEN-NIHTNLAIAQKLMELKLGKIN-
QNCASIITEAFQKPKEVPQAKETLIDTVISSFNIETAHDDSNCNITREHVCIYRKNENEP
GSLQNSQRDYRETAYIE---DKGQDHSLFCNSQLNNNIC---LNINFK-EQRDNYKE---
---NQNEAKE-N-NASSEENNLENIYGDEKQGSHTN--ENFSI-IDEKEE-DKNYNIEIL
SSEEFSTTFNLICREK-YASAETAFLES--EEDTISAMKQKDTE-NTGRSIEHLASTT-F
PEV---ASSSVCVASNAAVQIASATIPALS-TNNEDDQ---VKETCSSESPDFGLLVKHR
VSGCEIDMDKNKLQESFHQSIN-EN---LVLQSIELEREIEIELEDCDDAFV--FQLDTH
SHENVLCEEFVTSYKALKSRITWEGLLALDNGEIEVLESTTGRENSDQHYSKESNYFYSS
AQNNETELPSPILLPDLQIRIT-NIFRPGFSPTADSLALKDNFCTHIIDATKLEINKE--
----DEETLGFSIYSQPSGENTDYPCEDKVGNI-RQESGLVSKA-ETSLSFDLS-NNTDV
---NHISE-NQNSESLFTEPSNVT-AIDDGSGSFTTKSI-TVYNDTKNKKEVESRSNKRK
L-YTSSRDQDISYKDLRHHEICGRKRRRTSQDSSECFSSLSQGRIKTFSQSEKHIKSVLD
ILRGEASLCKSKRLSRKLNKAVIHLKKAHRRVHTSLQLIAKVGEK-GRGPLPKSYAIICN
NF-WESCDLQGYSSVSQRRYYSTKHFLSKRKYDKQRKKRALKAGISKSLTCVSKYKSYK-
R------SRG--KNCLSRKGMASSVSKSHPI-IHMGEFSNQE-HPESQFPVSSTSQITNQ
S-VYYNSSVSNPSLSEERQLFSGK-TRSLFSPNHSDEKLIEKENQVDTEFLSSISKYEKL
ENHSANH--K---DATKEKSCEINEVINESNSLSSSCIKENNIDYSTGN-DYDATCIDHT
KVKTDVLISVLDSNMEHFLNVDLYQQNNLLLSDGKRNLEVNFPIEKCTVPIERSKQNITT
RNFLMDPLNLTLIASKK-YSIPQLLSAAAVTDSEGESSKSYLDKQRILTIDSFAAST---
---TVSNCEQSCRGK--ELLKTEQCSSDNCLHTNGNETNVS-ENYELDVTS-VTEESKS-
-YGENV-------V-KLSSSDSSVLLKDNVKGSSSETCTVKKDTEDRIMQKVKQAEKA-K
DSV----YK-SMTE-GSTVKTEYKNQKNQIS-EES-CLNEKMIKTNLIDSHLS-TENTST
V-SVSLKSTVSNPL

PF15326 // ENSGT00390000006260_0_Domain_1 (2115, 2382)

NKRE-KKGEIKV-SNVSQS---------------------------
-DLTLHSETACISK---PEILGVNHMPVLPAHSETCKVTTFL-KKPASYVSEFKNKHSSA
NHATLIAQLSQILQRADEASSLQILQEETKVCLNILPLFVEAFEKKQECSVEQILISREL
LVDQNLWNNWKHTLKPCAVDTLVELQMMMETIQFIENKKRRLEDKPTFRSLLWYDETLYA
ELLGKPRGFQQQSNFYPGFQGRLKYDAFCELQTYHDQLVEL

ENSGT00390000006260_0_Linker_1_2 (2382, 2544)

LEETKREKNSYYAFLKYKR
QVNECEAIMKHCFDCFDFSLSVPFTCGVNFGDSLEDLEILRKSTLKLISVHG-DSPKVHS
YPGKQDHLWIIIEIISSKVNFIKNNEVVCIKISLYGLEHIFFDAAKNLVWKERGQSFSKN
-SQKKDEERLLTVNKYASSKLQE

PF15326 // ENSGT00390000006260_0_Domain_2 (2544, 2722)

IYDTLSKDLNNEP-ISSIGLEDTV-IAS--RNNPINK
ATISIENCKLNS---TLLAHPDICCISEILDQAEFADLKKLQDLTLRCTDHLEILKKYFQ
MLQDDNIDNIFITEENVLDTMKNHSHAAIILKPEAIEMYIEIVMVSETIHFLKNSIAKKL
DKQRFRGMLWFDLSLLPELVQYQEKMASFSFLKENSTDVCLWKVIETAISELKKDLDIIY
KYNE-AVNCSYALHLISRELQELSEIKKLLKKSEYPSSTYIEFVPYIASINYGSTITELE
YNYNQFSALLKTIMSAPRKDLGKMAHIMKVMKTIEYMKIICAKNAELTISFILCQMLCNR
RKILQ-LKRKEELNIHVVKPEENINKSSISM-MIPPISECLIKNISKSPKKQPSSADKCE
D-SQEQQKN-TVSSRKKLKVDMKDVTKISREKATFKHPRTTGSHPQSVKKIISSSSNNLK
RNHL-TPKKVEMQRSLPGSL--LENPKDTCTSKSESKIDLT-VS----EHFTGQQKNL-T
SMKK--TNVNFSAAKTKSDSKDCAAFAICDQKSVHG-TFSPDHETVMQKFLKNSSDPTQK
SCLSDINPGTDVSLVPDT-SVLSKPIICFEKDSHIDLEMN-DTVFKLQDNDIVNSSIKNS
T---CMTSPEPICIQNKIPTLQINKLQPAETESEDKYMMDTLNPNVVHTLGASGHISLNV
NQTAEYSFSEQQ--NDENSKVLTQNAATYWNELPQSACTPVYNSSENLFG-TSSPYYSGY
VYHYSS--SNGNAITQTFQGITSYEVQP---PSSGLLTTVAS-----TTRSTHSNLLYSQ
YFTYFAGEPQANNFVPVNGYCQSQIPAAYNFQQPIFSQYASHQPLPQATYPYLPNVVVPP
EVPWTYAPWH-QQSFHPGH--

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--

PF12509 // ENSGT00390000006260_0_Domain_0 (123, 279)

MRESGRHCRELEEHFCFLALPQSDVAQIYQNGISTRA--STLKILGNPLLGIYMFRHV
DIALNYSHSRSITVESILIFKV-LFGKVK------KIQPSVDKNKVSLDPSPNFDCHMSR
NGPSLKDTIE-LQAYSSAVYFYEYSVLSKPVDKPRQCLPYAVVTVKFLGSKVDNGYLMTS
LRFLSTGFPKRTERTCSLNNCTVAKRIGKGKDATVIFEHFKKPVDPF---VQENCLCNVL
NSEINPSNSHISNSYGNVQNG-NISIPEAYNGQTEHNLAEIRDTSQVLAHDSDLSLMPSD
AKESV-NGDLLLNWTSLKNILSSLNAAYPLHNNTGSSTVTTSKFIKDPRLMRREESMGER
SNTAGLNEILQFEKSLDNVNSEIK---STPSNSASSSEVVPGDCAVLTNCLDAPCFKTCV
NDSQSWAHNTGSEDYDCIPPNKVTMAGQCKDQ---G-NFSFPISVSNVVSEVENQNHSEE
KVQRAQQ---------------------------ESG---NAYKKEYNSRISQESQSSDL
KTIYQTGHQMS-TIFPLKKKVS-IDEYLQNTGKMKNF-TDLKDNS--KHEEKQTSWKEID
N-DFTNETKISPMDNYIVLHQE--YKESESHNSFEKSCDKILITQEL-EIPK-SSTSTIK
DKDELDHLTLEWQ--IT-PSLESLSQKHPQHSVEYED-NIHTSLAVSQKLMELKLGKIN-
ANCASIITEAFPKPKDIPEAKEMLIDTVISSYNIETAHGNSNCSITREHICVHRKNENEP
VSLENIQRDYKETAYVE---DRGQDHSLFCNSQL-NDIC---LNVNFR-EQRDNYKE---
---SQNEAKE-S-NAS---------SGDRKQDSHTS--ENFSY-IDEKED-KNYNNIEIL
SSEEFSATFNLICREK-YVSAATALLES--EEDTISAMKQKDTE-NTGRSVEHLASTA-F
PEI---ASSSVCVASNAAVQIASATMPVLS-ISNDEHQIYQFKETCSSESPDFGLLVKHR
VSDCEIDKDKNKSQESFHQSIN-EN---LVLQSIELESEIEIELEDCDDAFL--FQQDTH
SHENMLCEEFVTSYKALKSRISWEGILALDNGEMEVLESTAGRENSDQHYSEESNYFYSS
TQSSETELPSPILLPDLQIRIT-NIFRPGFSPTVDSLALKDNFCTHVTEATKPEINKE--
----DGEILGFDIYSQPSGENSDYPCEDKVDNI-RQESGPMSKS-EISLSFDLS-HNTDV
---NHRSK-NQNSESLSSEPSNVT-TIDNGSRCFFTKSK-TDYNDTKNKKEVESSISKRK
L-HTSSRDQNI-HKDLRQHKIYGRKRRLTSQDSSECFSSLSQGRIKTFSQSEKHIKSVLN
ILSGEASLCKSKCLSKKLDKAVTHLKKAHRRVHTSLQLITKVGEK-RKGPLPKSYAIICN
NF-WESCDLQGYSSVSQRKYYSTKHFLSKRKYDKRRKKRAPKADISKSLTYVSKHKSCK-
T------SGE--EKCLSRKSMASSVSKSHPT-IHVGEFCNQE-HPESQLPVSSTSQSTSQ
S-VYYNSSVSNPSLSEEHQPFSGK-TGCLFSPDHSDEKLIEKENQIDTKFLSSTSKYEKL
EKHSANHNVK---DTTKENSCEANQVINESNSISLSCIKE-NINYNTGN-DYDATCIGCT
KVKTDVLISVLDSNVKHFLN-DLYQ-ENLILSDYKRNLEVKW-----TAPIERSKQSIIT
GNFLMDPLNLTLIASKK-YSIPQL-SASAVTDSEGESSKSYLDNQRILTIDSFAAST---
---TIPCCEQSCRGK--ELLKTEQCSSGNCLHTDGNETNVT-ENYELDIAS-VTEESRS-
-YGENI-------V-KLSSSDSSLLLKDNVKGSSSETCIVKKDTEDRIMWKVKQMEKA-K
DSV----YKSSMTE-GSTVNTEYKNQKNQIS-EES-CLNEKIIKTNLIDSHLS-TKNTTT
E-SVSLKNTVSNPLNKRE-K-VEIKV-SNDSQS---------------------------
-DLTLHSEIAYISK---PGILGVNHTPVLPAHSETCKVTTLL-KKPASYMSELKEKHCSA
NHTALIANLSEILQRADEASSLQILQEETKICLNILPLFVEAFERKQECSVEQILISRER
LVDQNLWNNCKHTLKPSALDTLVELQMMMETIQFIENKKRRLEGEPTFRSLLWYDETLYA
ELLGKPRGFQQQSNFYPGFQGRLKYNAFCELQTYHDQLVELLEETKRENNSYYVFLKYKR
QVNECEAIMEHCSDCFDFSLSVPFTCGVNFGDSLEDLEILRKSTLKLISACG-DSPKVHS
YPGKQDHLWIIIEMISSKVDFIKNNEAVRIKISLYGLEHIFFDAAKSLVWKEKTQSFSKK
YSQKEDKERLLRVNKCAFSKLQKIYDTLSKDLNNEP-ISPVGLEEDTIIASRKSDHPINK
VTISIENSKFSS---SLLAHPDIYCISEILDQAEFADLKKLQDLTLRCTDHLEILKKYFQ
MLQDDNMDNIFITEENVLDVVKNHSHEAILLKPEAIEMYIEIVMVSETIHFLKNSIAKKL
GKQRFRGMLWFDLSLLPELVQCQEKMTSFSFLKDNSTDVCLWKVIESAISKLKKDLDIIY
KYDE-AVNRSYAIHLLSRELQELSEIKKLLKNSKYFISTYIDFVPYITSINYGSTMMELE
YNYSQFSTLLKNIMSAPRKDLGKMAHIMKVMKTIEHMKIICAKNAELTISFFLCQMLYNG
RKILQ-LKRKEKMNIHVVKPGENNNKFSISM-MVPPISECINKNISKSSKKRPSTVDKCE
D-SQEQQKNTTISSCKKLKVDMKDVTKINRENATFKHPRTTGSHPQSENKIVSSSSNNLK
RNHL-TSKKVEMQRSLPGSLLPLENPKDTCTSKSESKIDLT-VSSDAPDHFTGQQENL-N
SMRK--RNVNFSAVETKSNEKDCAAFAICDQKSAHG-TFSPDREILLQKFLKNSPDPSQK
SCLSDINPGTDVSLVPDA-SVLSKPIFCFVKDIHTDLEMN-DTVFELQDNDTVNSSIKNS
S---CMTSPEPICIQNKIPTLQINKLQPAETESEDKYMKNTLNPNTVHTFGASGHITLNV
NQGAEYSLSEQQ--NDKNSKVLTQNTATYWNELPQSACTPTYNSSEHLFG-TSYPYSAWC
VYHYSS--SNGNGITQTYQGITSYELQS---PPSGLLTTVASGQGAQCAQGAHSNLLYSQ
YFTYFAGEPQANGFVPVNGYFQSQIPA-YNFQQPVFSQYASHQPLPQTTYPYLPNQDVPP
EVPWVYAPWH-QESFHPQH--

-------------MEMKEIAKRKTLWKMSST----SEPLLITGVEVNPLKKFTIPKIRRT
AGKVYLSPCCTNTREYSFIHDTLNQCRLDVSCDLQS-SWQFGDTKLVHNEELEKKFSAKR
S

PF12509 // ENSGT00390000006260_0_Domain_0 (122, 279)

EMRESGRHGRELEEHFCFLALPQSDVTEICQNGISTKA--STLKILGNPLLGIYVFRHV
DVALNYAYSQSIAVESIIIFKV-LFGKVK------KIQPSVDKNKVSLDPSPKFDCHMSR
SIPSLKDAVE-LQAYSSAVYVYEYNVLSKPVDKPRQCL

ENSGT00390000006260_0_Linker_0_1 (279, 2114)

PYAVLTVKFIGQKVDNGHLVTS
LR-LSTGFPKRTERACSLNNCTVAKRIGKGKDATVIFEHFRKPVDPF---VQENCSCNTL
NSEINSSSSNISNSCGNVQNG-NISILETYHGQTEHNLAEIRDTSQVHAHDSGLSVISSD
TKENV-NGDHLLNLTYLKNVLSGLSAAFPLQNNIGSSTVITSKLIKDPRLLRREESMGKQ
NDTAGVNEILPFEKSLGYVNSEIN-LSSTPTSSAS-SEVITGDCSLLTNCLDAPAFKISF
DDSQSQAPNMGSKDYDFTTLDKTTMTGQCKNQ---E-NFSFPVSFSNVISEVENQKHNGK
EAQRAQQESNIPLSIKQHSEPHN---------SYESM---NTCTKECSSHISQESQSSDL
KTIYHTDHQLS-TIFPFQKKES-INEYIQNIGKMRNF-TDLEDSF--KHGEKQTLWKEID
--YFTDETKIHPVDNYVSLCQE--YKDSESVDSLGENCDKILITKEL-EIKK-SSTPATK
DKDKLQHLALELQS-IT-PGVESLSQKHPQYSLEYED-NIYTNFAIAQKLMELKLEKTT-
QNYVSIMTDVFQEAKDIPQAKEMLIDTVISSHDIETAPENSNCNITREHVCVHRKSENEP
LSLGNIQRDCKGPHH-----TEGQDYTVFFNAQLNNDLC---LKVNFR-EQGDNDKE---
---NQNEAKET-------ENNMESIHGDEKQSFHTN--KNVTN-IDERKENKNYNNVEIL
SSEEFSTTVNLIWGGK-YVSTETALLES---KDTINVAQQKDTQ-NTGRSVEHLAATK-F
PEI---SSSSVCVSSNASVPIASTTVPTLS-TDHEDPHRYQFKETCSSESPDFGLLVKRR
VSDCEIDTDKNKLQDSFHQSKS-ED---SVLQNFELENEIEVGSEQCDDACL--FQQDAH
SHENVLYEEFEALYEALKSRIDWEGLLGSNNGETEILKSTTRRENNDQHYSKESNCFYSS
TEKNKTEFLSPILLPDLQIRIT-NIFRPEFSPTADPLVLKDNFQKCITEMTNPEINKE--
----GGEALGFEICSQPSGKNSGYPGEDKLANM-LQASRLVSKS-EISLSFDLS-QNTHV
---NHMSE-RQNSESLFTEPS-TA-TINDGSRCSFTKSK-TDRNDTRSKKEVEIRTSKRK
L-RTSSRDQSISPKDLRPHEICGKKRRLTSSDPSECFSSLSQGRIKTFSRSEKHIRSVLD
ILNSEASLCKSKRLSRKLDRAVVHLKKAHRRVHTSLQIIAKVGEK-RKGPLPKSYAIICN
NF-WESCDLQGYSSVSERRYYSTKHFLSKRKYDKQGERRVLGFDVDKSLTHGSKHKSYK-
L------SGEKITKCLSKKSVASSVSRSHTT-IHVREFCDQEQHLESQLSLSSISQSTHQ
P-VYSNNSMRN-PELSELQPFSRK-TGHLSSSDHSDEKVTEKENQIEAKFLSNISKYEKL
ESHSARDNTK---DAAEEHKCEASEVINESNSVSLNCIKENNISYSTDK-NYDATCIAHT
KVETDILISVLESNVEHFLNVDMCKQDNLILSGCKRNLKVSFPIEKWTAPIKSCKRSIIT
GNFLMDPLNLNMIASKK-YSIPQLFSTTSVTDSEEESLKSYLGKQKIFAIDS---C----
---ATSHYQQIGSGK--EILKTEQCSSSNCFHIDGNETIVT-EKSELDLTS-ATEESKG-
YYGKNK-------MK-LSSNDSSLLLKDNIKGSS-SKYTVKKDIH-RKMCKVKQAEKA-K
DSV----YKRNMTE-GSTVKTEYKNQKNEILKEDSSHLNEETIKNNLIDSHLS-TKNTTK
A--VSLNYLVFNQ

PF15326 // ENSGT00390000006260_0_Domain_1 (2114, 2382)

LNKRE-KKGEIKI-INDSQS---------------------------
-DLMLHAETAYVSK---PDILGVNHMPILHAHSETSKVTTHQ-KKPTSYVNELNEKHCSA
NHTALITKLSQILQRADEASSLQVLQEETKVCQNILPLFVEAFERKQECSFEQIVISREL
LVEHNLWSNCKCKLKPCAVDTLVELQMMMETIQFIENKKRLLGGEPTFRSLLWYDETLYG
ELLGRPRGYQQQSNFYPAFQGRLKYNAFYELQTYHGQLIEL

ENSGT00390000006260_0_Linker_1_2 (2382, 2534)

FEETKRGDNSYYAFLKYKR
QINECEAIMKHCSDCFDFSLSVPFTCGVNLGDSLEDLETLRKSTLKLISIYG-DSPKVHS
YPGKQDHLWIIIEMISSKVNFIKNNEALSIKISLYGLEHIFFDAAKSLVWKEKRQSFSKK
YSRKNNKEMLLKM

PF15326 // ENSGT00390000006260_0_Domain_2 (2534, 2722)

NQCAFSKLQKIYDTLSKDLNNEP-ISNTRLEKNTVIASRKSDDL-NK
ATISIENYRFNG---TLLSHPDICGISEILDQAEFADLKKLQELTLRCTDHLEILKKHFQ
MLQEDNIDNIFITEENVLDMMKNHNRGAVILKPEAIETYVEIVMVSETVYFLKNSMAKKL
DKQRFRGMLWFDLSLLPELVHCQEKMASFSFLKDNSTDVCLSKVIETAISELQKDVDIIY
KYSE-AVNCSYALRLLSRELEELSEIKKLLKKSKYSVSTYIDFVPYVASINYGSTVTELE
YNYSQFSTLLKNTMSAPQKDLGKVAHIMKVMKTIEHMKIICAKNPKLAISFILCQMLCNR
RKTFQ-PKRKEKMNVHVTKPGENINKSSMSM-KVPLIPERIIKNVSNSSKKRRIAVDKCE
D-SEEQEKSTNISSCKKRKVNMKEIPKI-REKTTFKRQRSTESHPKSEKKMESTSSGNLK
RNHVLSPEKIEMQRLLPGSLSPLKNLKDSCSLKAESKIDL-NISSDTSQHFTGQQGNL-N
SMKK--KNKNFCAAETNSDKKDCAAFVICDQKSTDG-TFSKDHETFSQKFLKNSSDSTQQ
SCLLDIKPGADASLEPNT-SVLSKPVFHFVKDIHTNLEMN-DTVLELQDNEVLNSSIKNS
T---CMTSPEPIFIQKRIPVLEISKTQSAKSEAEEKYMKDTLNPSTI-SFEASGHITLNV
NQTAEYSFSEQQ--NDENSKVLTQNAATCRDELPQSACTPVYNSSENSFG-TSYPYYAWC
VYHYSS--SNGNTITQTYQEITSYEVQP---PSSGMLTAVAS-----TVQSTHSNLLYSQ
CFSYFAGEPQAHGFVPANGYFQSQMPISYSFQQPIFSQYASHQPL-QAAYPYLPNPAVLP
EFSWIYTPWQ-QEPFQPGR--

---------MANKMEMKETAKQDTLWQMSST----SKPVLNTR-EVNPLKKFTIPKIRRT
AEKVYLSPCYTNSREYSFIHDTLNQCRLDVNCDLQS-LWQFGDTKLVHNEELEKNFTAKR
S

PF12509 // ENSGT00390000006260_0_Domain_0 (122, 279)

EMRESGRHCRELEEQFCFLALPQSDVAQIYQNGISTRA--STLKILGNPLLGIYMFRHV
DIALNYSHSQSITVESILIFKV-LFGKVK------KIQPSVDKNKVSLDPSPNFDCHMSR
NAPSLKDTIE-LQAYSSAVYFYEYSVLSKPVDKPRQCL

ENSGT00390000006260_0_Linker_0_1 (279, 2115)

PYAVVTVKFLGSKVDNGRLMTS
LRFLSTGFPKRAERTCSLNNCTVAKRFGKGKDATVTFVHFKKPVDPF---VQENCLCNAL
NSEINPFISNISNSYGNVQNG-NISIPETYSGQTEHSLAEIRDTSQVLAHDSDISLMPSD
AKDSV-NGDLLLNWTSLKNILSGLNASFPLHNNTGSSTVTTSKSIKDPRLMRREESMGEQ
SSTAGLNEVLQFEKSSDNVNSEIK---STPSNSASSSEVVPGDCAVLTNGLDTPCFKTSV
NDSQSWAHNMGSEDYDCIPPNKVTMAGQCKDQ---G-NFSFPISVSNVVSEVENQNHSEE
KAQRAQQ---------------------------ESG---NAYTKEYSSHIFQDSQSSDL
KTIYQTGCQTS-TVFPLKKKVS-IDEYLQNTGKMKNF-ADLEDSS--KHEEKQTSWKEID
N-DFTNETKISPIDNYIVLHQE--YKESESHNSFGKSCDKILITQEL-EITK-SSTSTIK
DKDELDHLALEWQ--IT-PSFESLSQKHPQHSVEYEG-NIHTSLAIAQKLMELKLGKIN-
QNYASIITEAFPKPKDIPQAKEMFIDTVISSYNIETAHDSSNCSITREHICVHRKNENEP
VSLENIQRDYKETAYVE---DRGQDHNLFCNSQLSNDIW---LNVNFK-KQTD--RE---
---NQNEAKE-N-SASCVENNIENIYGDKKQDSHTN--ENFSN-IDEKED-KNYHNIEIL
SSEEFSTKFNLICREDNAVSAATALLES--EEDTISAVKQKDTE-NTGRSVEHLASTT-F
PKT---ASSSVCVASNAAIQIASATMPALS-LNNDDHQIYQFKETCSSESPDFGLLVKHR
VSDCEIDTDKNKSQESFHQSIN-EN---LVLQSIELESEIEIELEDCDDAFI--FQQDTH
SHENMLCEEFVTSYKALKSRISWEGLLALDNGEMEVLESTTGRENSDQHYSKESNYFYSS
TQNNETELTSPILLPDLQIKIT-NIFRPGFSPTADSLALKDSFCTHVTEATKPEINKE--
----DGEILGFDIYSQPFGENADYPCEDKVDNI-RQESGPVSNS-EISLSFDLS-RNTDV
---NHTSE-NQNSESLFTEPSNVT-TIDDGSRCFFTKSK-TDYNDTKNKKEVESRISKRK
L-HISSRDQNIPHKDLRRHKIYGRKRRLTSQDSSECFSSLSQGRIKTFSQSEKHIKSVLN
ILSDEASLCKSKCLSRKLDKAVVHLKKAHRRVHTSLQLITKVGEE-RKGPLPKSYAIICN
NF-WESCDLQGYSSVSQRKYYSTKHFSSKRKYDKRRKKRAPKADISKSLTHVSKHKSYK-
T------SGE--KKCLSRKSMASSVSKSHPTTSHMGEFCNQE-HPESQLPVSSTSQSTSQ
S-VYYNSSVSNPSLSEEHQPFSGK-TAYLFSPDHSDEKLIEKENQIDTAFLSSTSKYEKL
EKHSANHNVK---DATKENSCDANEVINESNSVSLSCIKE-NINSSTGN-DCDATCIGHT
KAKTDVLISVLDSNVKHFLN-DLYQQGNLILSDCKRNLEVKW-----TDPIERPKQNIIT
GNFLMGPLNLTLIASKK-YSIPQL-SAAAVTDSEGESSKSYLDKQRILTVDSFAASS---
---TVPHCEQSCREK--ELLKTEQCSSGNCLHTDGNETNVT-ENYELDVAS-GTEEDKS-
-YGENI-------V-ELSSSDSSLLLKDNVKGSSSETCIVKKDTEDRITWKVKQAEKA-K
DSV----YKRSMTE-GSTVNTEYKNQKNQIS-EES-CLNEKIITTNLIDSHLS-TKNTTT
E-SVPLKNTVSNPL

PF15326 // ENSGT00390000006260_0_Domain_1 (2115, 2382)

NKRE-KKGEIKV-SKDSQS---------------------------
-DLTLHSEIAYISK---PGILGVNHTPILPAHSETCKVPTLL-KKPASYVSDFKEKHCSA
NHTALIANLSQILQRADEASSLQILQEETKVCLNILPLFVEAFERKQECSVEQILISREL
LVDQNLWNNCKHTLKPCAVDTLVELQMMMETIQFIENKKRHLEGEPTLRSLLWYDETLYA
ELLGKPRGFQQQSNFYPGFQGRLKYNAFCELQTYHDQLVEL

ENSGT00390000006260_0_Linker_1_2 (2382, 2585)

LEETKREKNSYYVFLKYKR
QVNECEAIMEHCSDCFDFSLSVPFTCGVNFGDSLEDLEILRKSTLKLINVCG-DSPKVHS
YPGKQDHLWIIIEMISSKVNFIKNNEAVRVKISLYGLEHIFFDAAKNLVWKERTQSFSKK
YSQKKDEERLLRVNKCAFSKLQKIYDTLSKDLNNEP-ISPIGLEEDTIIASRKSDHPINE
ATIS

PF15326 // ENSGT00390000006260_0_Domain_2 (2585, 2722)

IENSKFNS---NLLAHPDICCISEILDQAEFADLKKLQDLTLRCTDHLEILKKYFQ
MLQDNNMDNIFITEENVLDVVINHSHEAIILKPEAIEMYIEIVMVSETIHFLKNSIAKKL
DKQRFRGMLWFDLSLLPELVQCQEKMASFSFLKDNSTDVCLWKVIETAVSELKKDLDIIC
KYNE-AVNCSYAIHLLSRELQELSEIKKLLKKSKYFISTYIDFVPYIASINYGSTVTELE
YNYNQFSTLLKNVMSAPRKDLGKMAHIRKVMKTIEHMKMICTKNAELTISFFLCQMLYNR
RKILQ-LKRKEKMNIHIVKPGENNNKFSIST-MLPPVSECINKNISNSSKKRPSTVDKCE
D-SQEQQQDTTVSSCKKLKVDMKDVTKINREKATFKHPRTTGSHPKSENKIVPSSCDSLK
RNHL-TPKKVEMQRSLPGSLLPLENPKDTCASKSESKIDLT-VSS---DHFSGQQENL-N
SMKK--RNVNFSAAETKSDKKDCAAFAICDQKSVHG-TFSPDHGTLLQKFLKNSPDPTQK
SCLSDINPETDVSLVPDA-SVLSKPIFCFVKDVHPDLEMN-DTVFELQDNDIVNSSIKNS
S---CMTSPEPICIQNKIPTLQINKLQPTETESEDKYMKDTLNPNTVHTFGASGHITLNV
NQGAEYSLSEQQ--NDKNSKVLMQNAATYWNELPQSACNPTYNSSEHLFG-TSYPYSAWC
VYQYSN--SNGNAITQTYQGITSYEVQP---SPSGLLTTVAS-----TAQGTHSNLLYSQ
YFTYFAGEPQANGFVPVNGYFQSQIPA-SNFRQPIFSQYASHQPLPQATYPYLPNRFVPP
EVPWVYAPWH-QESFHPGH--

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------SIEKTCSLNNCTVAKRIGKGKDATVIFEHFRKPVDSF---SQENCPCKAL
TSEIGSSSLDSSSSYGSVQNG-NNSVCEVYSRQTDN-SSEVRDATEVHTHNSGLYFMPTA
NTASG-NGDL-FSVTYLRSILSSISAALPSQSSTGSSTVITSKLIKDPRLLKREQSMRKQ
NNA----DVLPFDKSAGHGNSEIK-LTCMPASSVSSPETTPTGHAL-TNCSDVSCFKFSS
ERSHCETHNMGSRDYDCTASSKIAITEQFKEQ---S-WFSFPCYLPNAFSNVGKQKYNEE
---EAQKSSNIPLLPEQSNEPQN---------SFESE--KNTCSKDYQSHISTASWSSDL
NTAYKVDHKMS-AVSPIQKKGN-LDEYVKNTAMMRTF-ISPEDSS--EHV-NQTWYKETV
H-YCTDETICSPIDNCITLHQE--HKECGNLNSLKGNCEKTPVTHKL-QMPK-PSISTTE
DKSELDRAAVELVCSLT-PHIGCLVQKHPQYPLEHND-NIQTNFVMTQGLTELKAVQNN-
QRFINV-TDAFQEAKDVPQAREQLIGRVISSSATDVSLDSSGCDMIGEYMCIQSENKNET
VSMYNLQKDCKETSHIK---DDVHDHCLSYVN----------LKINLQ-EERD--NE---
---NPNEAKEKDN----------NTNESEKQDFH-------AN-TVEMREIKSNTKVQIL
NSEECS-TFDSIWGKK-GRPAKSTSSES---EGSMASLKQSHTP-NDGRSVEPFVST--F
PET---ECSSVCVASSATKQVVNTTLLTLN-TNFEDHEKYQLKETCDSEISDLCL-VKHG
VSDCEIDTDKDRLQN-FYQLVN-EN---SVLQTFGLGSEIEVELEDYNDTSL--FPQNID
SQGHVFCEEFE-LYESLKSRIAWEGLFGNSNEEMQTSNFAQR-ESTDPH-STECNCVSFL
SQKDKRELHNPMFLPDLQVTIT-NLISLRIGPTNDSLESKDNFYKRVTESTEPEANEE--
-----EKAFGFSIYSQPSEENSGFSCENKHN-S-VQESGHVSKS-GISHSS-----NMCV
---NHIPG-KSNNNSLSTEPSKVT-VINEKSNC-PTKSK-FDLNDTENKKDMESRSSKRS
PHVS-SRRQNISHKDIRQHETHEKRRKPTSHDSSEHFSSLSQGRIKTFSQSERHIRSVLN
ILNNEASLCKSKHLSRKLDKAVLHLKKAHRRVHTSLQLISKVGKK-RKGPLPRAYSVVCN
NF-WESCDLQGDSWMSERRS--SRHFSSKRRYEKQGEKR-LRFDIDESLAPVSKHRSYR-
T------NRERLPECLSSRIMSGHVSSSLTT-FHVRKFCDE-QLHKSQLPLACTSQCISQ
L-ECTNCIVRN-ASSSELEHFSET-RGPTLY---PDETLTEKECQTDTQIS--NSESTKL
GNHSAHN-IK---DIIKENNSEDKTVVCESNSVSLSSMKEN-ISHSQDK-SYGLTCKAN-
---NDILNSVLDSNKKQFLNVGICEQDNLVS-DGVRNGDTILSVEKCTVLREIT--P---
----SIPTGN----------IPPL-SPILVTAGEE---------NG--------------
------------------------------LHVKENEVNIT-KHSKLYLMS-VTEESKS-
-CKKSI-------K--LSSNDTFLLLKENVKGP--SKTYMEEYIEEENMRKIEQTV----
-------YQKVVTE-GSAAVTRYKCQNKTLK-EESFHSHKKIIKN-VTDSCLG-IKNSTL
E-TIALENIPS-QLSKRQ-KVGQMKQ-----PP---------------------------
-A--------CPSK---PAAAGTNHRPILH

PF15326 // ENSGT00390000006260_0_Domain_1 (2191, 2381)

DNTEGLNE-----ER---------------
VAKSRVTELSQILQKADKAVSLQVLEEEAKVCQNLLPLFVKAFERKQECSLDQILISRKL
MVEQDLWDNCRLKLKPSAVDTWVELQMAMETIQFIENKKRSLEGEATFRSLLWYDESLYS
ELLSRPRGYQLQSNFYPAFQRRLKYNAFCELQSYYHQLVE

ENSGT00390000006260_0_Linker_1_2 (2381, 2603)

FLTKTKKENNSYYTFLKYKR
QIKECEAIMRHYSDCFDFCLSVPFTCGVNFGDTLADLEALRKSVLKLINMHA-GSPKVHS
YPGKEDHFWIILEVVSSKVSFVKNNEEVSIKICLYGLEHIYFDAAKSLVQKEKSHSFPKR
HSEK-NRE-MEAVNECAISKWEKIYDVLSKDLNDES-TPTIGLEED-RIMSRQSA-LV--
---SLPNCTLNK---AWLSYPD

PF15326 // ENSGT00390000006260_0_Domain_2 (2603, 2723)

ICCISEILDQAKSADLKTLQDLTLRCTVHLKILKKYFQ
MLQEDNVDNIFVTEENVLDIL-SHKCGAVILKPEAIEIYIETVMLSETIHFLKNSIAKKL
HNQRFRGMLWFDWSLLPELVNCQKEMVSFSV-DDNQTD-CLWKVIESAISHLKKELCVLY
DYSE-AVNCSYALRLFSRELKELLGIKRLLNTSKYSVSTYIDLAPHIACVNYGNTVEELE
YNYNQLFKLLKNIMSVPQKDFGKMVHIIKVLKTIEHMKMIRAKGTKLSTDLLFFQMLRNR
RNTLQ-LSRKEKMDTATTEPEDNSSQPDISV-QTPSAAGCTIS----SSKKRPVTADKCE
V-S------DAVSNCKKQKVTMKDVR--NRQKTMSKNPRTTKSHPKDENRIGSNSSDNLT
RDSA-SPEMVKGQNSTPGSLSPSENIEGTFTPNSESKIELTDSSSDASEYLPEQQESL-N
GIMK--GNVNLNAAQSD--KKEH-PLVPCNQKDIAA-TCSPDNSP-LQKLHETPADH-TQ
ICPSNMKPRNDDPLVPNA-SV---PASCSVRAIHSNLETN-DTDFEHEDNEILDLSIKDC
T---CTSSPEPVCIQDKIPVVQVNKIQPI---------KDALNPSTS-PFGSYGSSALEV
NQRAQHTVSKQN---GKNPNVLTQKVDTSWNAPPQSTYTAVYNSSEHSFG-TSYPYYAWC
FYQYSS--S-STAVAHTYQGMTTYET------PPPMMTAVAS-----AVQNTHFNHSYSE
QFSYFARQPQANAFIPGNGFSPSPLPVSYSYQQPAYSQFAPHQLVPQAAYPYPPNPGVLP
QAPWTYGELK-SSVFGSFLL-

---------MANKMEMKETAKQNTLWQMSST----SKPVLNTR-EVNPLKKFTIPKIRKT
AEKVYLSPCYTNSREYSFIHDTLNQCRLDVSRDLQS-FWQFGDTKLVHNEELEKNFTAKR
S

PF12509 // ENSGT00390000006260_0_Domain_0 (122, 279)

EMRESGRHCRELEEHFCFLALPQSDVAQICQNGISTRA--STLKILGNPLFGIYMFRHV
DIALNYSHSRSITVESILIFKV-LFGKVK------KIQPSVDKNKVSLDPSPNFDCHMSR
NAPSLKDTIE-LQAYSSAVYFYEYSVLSKPVDKPRQCL

ENSGT00390000006260_0_Linker_0_1 (279, 2115)

PYAVVTVKFLGSKVDNGRLMTS
LRFLSTEFPKRAERTCSLNNCTVAKRIGKGKDATVIFVHFKKPVDPF---VQENCLCNAL
NSEINPSISNISNSYGNVQNG-NISIPETYSGQTEHNLAEIRDTSQV--HDSDISLMPSD
AKESV-NGDLLLNWTSLKNILSGLNASFPLHNNTGSSTVTTSKFIKDPRLTR-EESTGEQ
SNTAGLNESLQFEKSLDNVNSEIK---STPSNSAFSSEVVPGDRAVLTNGLGTPCFKT--
--SQSWAHNMGSEDYDCIPPNKVTMAGQCKDQ---G-NLSFPISVSNVVSEVENQNHSE-
KSQRAQQ---------------------------ESG---NAYTKEYSSHIFQESQSSDL
KTIYQTGCQTS-MIFPLKKKVS-IDEYLQNTGKMKNF-TDLEDNS--KHEEKQTSWKEID
N-DFTNETKISPIDNYIVLQQE--YKESESHNSFGKSCDKILITQEL-EITK-SSTSTIK
DKDELDHLALEWQ--IT-PSLESLSQKHPQHSVEYED-NIHTSLAIAQKLMELKLGNIN-
QNYASIISEAFPKPKDIPQAKEMFIDKVISSYNIETAHDSSNCSITREYMSVHRKNENEP
VSLENIQRDYKETTYVE---DRGQDHNLFCNSQLNNDIC---LNVNFK-EKRD--KE---
---NQNEAKE-N-SASSVENNIENIYGDKKQDSPTS--ENFTD-IDEK-D-KNYNNIEIL
SSKEFSTAFNLICREK-YLSTATALLEN--EEDTISAVKQNDTE-NTGRSVEDLASTT-F
PKT---ASSSVCVASNAAIQIASATMPALS-LNNDDHQIYQFKETCSSESPDCGLLVKHR
VSDCEIDMDKNKSQESFHQSIN-EN---LVLQSIELESEIEIELEDCDDAFI--FQQDAH
SHENVLCEEFVTSYKALKSRISWEGLLALDNEEMEVLESTTGRENSDQHYSKESNYFYSS
TQNNETELTSPILLPDLQIRIT-NIFRPGFSPTADSLALKDNFCTHVTEATKLEINKE--
----DGEILGFDIYSQPFGENADYLCEDKVDNI-RQESGPVSNS-EISLSFDLS-HNTDV
---NHTSD-NQNSESLFTEPSNVT-TIDDGSRCFFTKSK-TDYNDTKNKKEVESRISKRK
L-HTSSRDQNISHKDLRRHKIYGRKRRLASQDSSECFSSLSQGRIKTFSQSEKHIKSVLN
ILSDEASLCKSKCLSRKLDKAVVHLKKAHRRIYTSLQLITKVGEK-GKGPLPKSYAIICN
NF-WESCDLQGYSSVSQRKYYSTKHFLSKRKYDKWRKKRAPKADISKSLTHVSKHKSYK-
T------SEE--KKCLSRKSMASSVSKSHPT-SHVGEFRNQE-HPESQLPVSSTSQSTSQ
S-VYYNSSVSNPSLSEEHQPFSGK-TGCLFSPDHSDEKLIEKENQVDTKFLSSTSKYEKL
EKHSANHNVK---DATKENSCEANEVINESHSVSLSCIKE-NINYNTGN-DYDATCIGHT
KAKTDVLISVLDSNVKHFLN-DLYQQGNLILSDCKRNLEVKW-----TDPIERSKQSIIT
GNFLMDPLNLTLIASKK-YSIPQL-SAAVVTDSEGESSKSYLDKQRILTVDSFAAST---
---IVPHCEQSCRGK--ELLKTEQCSSDNCLHTDGNETNVT-ENYELDVAS-VTEENKS-
-YRENI-------V-ELSSSDSSLLLKDNIKGSSSETCIVKKDTEGRIMWKVKQAEKA-K
DSV----YKRSMTE-GSTVNTEYKNKKNQIS-EES-CLNEKIIKTNLIDSHLS-TKNTTT
E-SVPLKNTVSNPL

PF15326 // ENSGT00390000006260_0_Domain_1 (2115, 2382)

NKRE-KKGEIKA-SNDSQS---------------------------
-DLTLHSEIAYISK---PGILGVNHMPILPAHSETCKVTTLL-KKPASYMSEFKEKHCSA
NHTALIANLSQILQRADEASSLQILQEETKVCLNILPLFVEAFERKQECSVEQILISREL
LVDQNLWNNCKHTLKPCAVDTLVELQMMMETIQFIENKKRHLEGEPTFRSLLWYDETLYA
ELLGKPRGFQQQSNFYPGFQGRLKYNAFCELQTYHDQLVEL

ENSGT00390000006260_0_Linker_1_2 (2382, 2586)

LEETKREKNSYYVFLKYKR
QVNECEAIMEHCSDCFDFSLSVPFTCGVNFGDSLEDLEILRKSALKLISVCG-DSPKVHS
YPGKQDHLWIIIEMISSKVNFIKNNEAVCVKISLYGLEHIFFDAAKNLVWKERTQSFS-K
YSQKKDEERLLRVNKCAFSKLQKIYDTLSKDLNNEP-ISPIGLEEDTIIASRKSDHPINK
ATISI

PF15326 // ENSGT00390000006260_0_Domain_2 (2586, 2722)

ENSKFNS---NLLAHPDICCISEILDQAEFADLKKLQDLTLRCTDHLEILKKYFQ
MLQDNNMDNIFVTEENVLDMVINHSHETIILKPEAIEMYIEIVMVSETIHFLKNSIAKKL
DKQRFRGMLWFDLSLLPELVQCQEKMASFSFLKDNSTDVCLWKVIETAISELKKDLDIIC
KYNE-AVNCSYAIHLLSRELQELSEIKKLLKKSKYFISTYIDFVPYIASINYGSTVTELE
YNYNQFSTLLKNVMSAPRKDLGKMAHIRKVMKTIEHMKIICAKNAELTISFFLCQMLYNG
RKIIQ-LKRKEEMNIDVVKPGENNNKFSISM-MVPPISECINKNISNSSKKRLSTVDKCE
D-SQEQQKNTTISSCKKLKVDMKDVTKINREKATFKHPRTTGSHPQSENKTVPSSSDNLK
RNHL-TPKKVEMQRLLPGSLLPLENPKDTCASKSESKIDLT-VSSDAPDHFTGQQENL-N
SMKK--RNVNFSAAETKRDKKNCAAFAICDQKSVHG-TFSPDHETLLQKFLKNSPDPTQK
SCLSDINPETDVSLVPDA-SVLSKPIFCFVKDVHTDLEMN-DTVFELQDNDIVNSSIKNS
S---CMTSPEPICIQNKIPTLQINKLQPAETESEDKYMKDTLNPNTVHTFGASGHITLNV
NQGAEYALSEQQ--NDENSKVLTQNAATYWNELPQSACTPTYNSSEHLFG-TSYPYSAWC
VYHYSS--SNGNAITQTYQGITSYEVQP---SPSGLLTTVAS-----TAQGTHSNLLYSQ
YFTYFAGEPQANGFVPVNGYFQSQIPA-SNFQQQIFSQYASHQPLPQATYPYLPNRDVPP
EVPWVYAPWH-QESFHPGH--

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--MTYFCIYVSTERACSLSNCTIAKRIGKGKDATVIFEHFRKPVDPF---VQENCPCKAL
NSEMGPSNSDASSSYGNVQNG-NSSLFEAYSGQIDN-SSEVRDASQVHTHNSDLSFMPTA
NAASG-NGDL-FSVTYLRSILSSISAVLPSQSSTGSSTVITSKLIKDPRLMKREQSMRKQ
NNSAGLSDVLPFDQSVGHGNSEIK-LTCMQASSISSPETARADNAV-TNYSDATCFRFSS
ESSHYQTPDMGSKDYDCTASSKIAITEQRKEQ---N-SFSFPHYLPNAFSDVGKQKYNEE
KAQRAQKESNIQVLTEQSNEPQK---------SYESG--KNTYSKDSPSHMSKALWSSDL
NDIYKVGHQMS-SLFPVQKTGN-LNEYMQNTRMMKTF-ISPEDSS--KHVVKQTWWKETV
D-YLTNETKSSPIDNCITLHQE--HKEDENLNPLRGNCEKRPVTHKL-QMPT-SPISTTK
DKNELDDAALELEYNLT-RNKWCLSQTHPHYSLEHKD-NIHTNFAMAQGLIELKAVQND-
QNFINIMTDAFQEAKDVPLAREQLIDRVISSSAIDVSLDSSGCNIVGEYMYIQRENENEA
VSLYNLQKDCRGSSHIK---NDVQDHSLSSDTELSSDLN---LKINLQ-EQKD--GG---
---NPNETKEKDS----------YNTDN--INEN-------EN-IVEMKETTSNTKGEVL
NSEECS-TLNAESAS---------------------SGSEDNAP-NDGRSVEHLVST--F
PEM---EGSSVCVASNATKQAVGTTVLTLS-TDCGDHQKHQLNKTCSSEISDLHL-VKHG
ISDGEIDIDKDKLQD-LDQLIN-EN---SVLQTFELGSEIEVELEECNEASV--LQENIH
SHGNVLCEEFE-LYETLKSRIDWEGIFGHSYEEMETSSFARK-EGTDPHHSTDCNCVSFS
SQKDKRELHNPVFLPDLQVTIT-NLISLRIRPTDDSSELKDNFYKHVTEPTESEA-DK--
-----EKAFGFGIYSQPSEENSGCSCENKFGNS-VQESGHVGQS-GISHSSDSS-HNTHV
---SHISG-KPDSDSLSTLPSNVT-VINDTNKC-PTKSK-PDFSDARNKKDIEPRSSKRS
LHAS-SRGQNISRKDLRQHETHEKRRKPTSHDSFERFSSLSQGRIKTFSQSERHIRNVLN
ILNNEASLCKSKHLSRKLDKAVLHLKKAHRRVHTSLQLISKVGKK-GKGPLPKAYAIICN
NF-WESCDLQGDSWMSERRY-STRHFLSKRRYDRQEEKRLLRFDFDESLAPVSKHRSYR-
S------DRERIAECLSSEIMSGHVSGSLTT-FHVREFCDEEQLHESQLPLAYTSQSINQ
L-EHTNSIGRN-ASSSELEHFSET-NGYMLY---PDETLTEKEYQTDTRLS--NSDSAKL
ENHSTHN-IK---DITRENNSEDKTVVCESNSVSLSFIKEN-VSHSRDK-SYDVTFKAN-
---TDILVSVLDSNKKCFLNDVICEPDNLVC-DDIRNGETIFPVGKCTVLTEIT--P---
----HIPTGN--TANRR-DTIPPL-SPSLVTAGEEESSMG---GNEL-------------
------------------------------FHIKENEVDIA-NQSKLDLTP-VTEE--I-
-CKKNK-------K-KLSSNDSSLLLKENVKGP--SKTYVAKYIEEEKMRKIEQAV----
-------YEKMITE-GSTVIVGYKHQNKIIK-EESYYLPKKINKNNLTGSRLG-IKNSTL
E-TITLKNILS-QLSKRQ-KAEQIKQL

PF15326 // ENSGT00390000006260_0_Domain_1 (2128, 2380)

SNYSPA---------------------------
-D--------CPSK---PTTAGTNHRPVVLENSEVTEL-----QEH-----------HLA
NYTSRMTELSQILQRADKAASLQILEEETKVCHNILPLFVEAFERKQECSLDQILISRKL
LVEQNLWNNCRLKLKPCAVDTWVELQMAMETIQFIENKRRFLEGEPTFRSLLWYDESLYS
ELLPRPRGYQLQSSFYPAFQGRLKYNAFCELQSYHHQLV

ENSGT00390000006260_0_Linker_1_2 (2380, 2603)

ESLTKTKQEKNSYYAFLKYKR
QINECEAIMNHYSDCFDFCLSVPFASGVNFGDSLGDLEALRKSVLKLISMHG-GSPKVHS
YPGKEDHLWIILEVVSSKVSFIKSSEEITIKICLYGLEHIYFDAAKSLVWKEKSHSFPKK
YSKR-NIE-MEEMNECAFSKWKKIYDVLSKDLNNEL-TPSIGLEDDDMIASRQSA-IV--
---SMPDCKLNK---AWLSYPD

PF15326 // ENSGT00390000006260_0_Domain_2 (2603, 2724)

ICCISEILDQAKSADLEKLQDLTLRCTVHLEILKKHFQ
MLQKDHIDNIFITEENVLDIL-NHNLGAVILKPEAIEIYIEAAMLSETIHFLKNSMAKKL
HNQRFRGLLWFDWSLLPELVGCQKEMASFSV-DDNQTD-CLWKVIETAISHLKKELGVIC
DYSE-AVNCSYALRLFSRELKELLGIKRLLNASKYSIPTYIDLAPHIASINYGNTVAELE
HNYSQLFALLKNIMSVPQKDFGKMVHIIKVLKTIEHMKMINAKGTKLSAHLLFFQMLRNR
RNTSQ-LNRKEKMDTPITEPEETGK--------TPSAAEGTVKSFSSSSKKRPVTVDKCE
V-SEGKGYTDAVSICKKQKVTMKDER--NGQKTVSKSPRTTASHPKDENKTGTNSFDSLK
RDSA-SQEMVQRQSSIPGSLSPSENIQDTCTPKSESKIEPTFSSCDVSEYLTEQQENL-N
IIKK--RNGIFSAAETN-DKEDC-PLVTCDEKDIDA-TCSPDNTP-AQKLHESPTDH-TQ
ICPSNIRAGNDDPLVPNS-SA---PISHSVRANHSNLEMN-DTGFKHEDNEVLNLSIKDC
I---YTSSPEPVCIQEKIPVLQVHKTQLVKTESPEMCVKDAPNPSTT-PFGSYGNSALDV
NQTAQHTLSEQD---GENPKVLTQKVGTSWNAPPQPTRTAVYNSSEHSFG-TSYPYYAWC
FYQYSS--SSGTAVTHTYQGMTTYETP----LPPPMMNAVAS-----SVQNTHFNHSYSE
HFSYFARQPQANAFVPGNGYSPFPMPVSYNYQQPVYSQFASHQLVPQAAYPYPPNPGVLP
QVPWTYAPWQ-QNPFPPRH--

-------------MEVKETKRGKSLSQRSASCRDHVAPGSSTSLEAHSLKNFTIPKIHRA
AEKVYLSSCHTNRREYSSISHTLSQCRLDLSCELQS-SWQFGETKL

PF12509 // ENSGT00390000006260_0_Domain_0 (107, 279)

VHNEYLEKKFSAKR
SEMREHGRRGRELEEHYCFLALSHSAVSRMYQSGLCTRE--STLKALGNPLLGVYLFRHA
DVALSYARSRKHHVDNLMIFKVVLYGKVK------KIQPVMDKSKACLDPSPNFDCHMSR
LIPTAKDIIE-QQAVGSAVYLYEYNTLSKPVDKPRQCLPYATITVKFLGQKAESGPTITS
LRFLSAGFPKWSEKRGSLNNCTIAKRIGKGKDATVIYEHFPKPTDSS---AQDSCSCNAE
------MNPDISSPCGSVQNN-SFFAVDTPDSQNDYNLTENHNLSQVQTIEANPPLLASV
GATQNVNGDLLINLNYLEKFFNTLSAAVTFPNSVGTSTVTTSKLIKDPRLLRRGVPHDQA
NPESGSQETLPLESREEYPDSQMNSLPSLPMAAALPPGAIPGEPMALNLGSPHPE-GLSH
D---AALKGVLSQNCDCRAIHEVVMDDPKEDQHHTDLQVPLPYASKEVIPEHDNREYIDK
EMDSSSEMNKILLPVKKQARGKCISEMNHFPRKGMPM---DTNSESLSNLVSQESQPDDL
KIVHEILQPSSPGLLQVQK-ET-RNKYNQGTQNVKSLNTDTENHS--QQGKNKYCKKKEN
Y-DSTHGEKSSSRECCVSYEKH---KVLILSHQDSNDCKKPRNQGTV-TIPM-RPS--TS
REQERKHIPWKSENSYPVLSTQKSSKNCLEEWLKCERMYIDKYFSKPPKVTELKMESLH-
LTPISMKANVSQEMDIIVQTKEKPNDLINLALDTEVSHSKVIRDGSEKYLGVSEGNENGL
LSPEDPHKDGKMDVCLA---EEADQ-SQVCPMN-----------EE---HNGS-------
----HPKEEGRE-SLSTEKNKMENIYVNEKQIVYMEE-NCTTM-VNNERDIKNLGRSEVI
HSEKFSSVFNFTWKKS-YMPLETALVEN---ESRVIPGSQRGILFSHKRKLMPLTSTTTL
SESTSSSAACVCKNSGANMPIPAALTPEFR-HEFEDNQRNFQGIAQAIQSPSFGACGRNI
FGEHQNDANYGRASEAHTQPTISEDQGVLPPQDLDFNNEIEVEFEQCEGSFL--QLQGTA
IHGNLPTDEMSSVYQLLESRIDWENLLGSQKP-SEISKSTWPQEDGSQCFLKECSCIYSW
TQKNHRDLLSPVVVPDLQVEIT-NIIQTRFTLSQEPLAMQGEVLVCPTPDTE--------
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--------MATNKMEMKETAKQNTLWQMSST----SEPMLNTR-EVNPLKKFTIPKIRRT
AEKVYLSPCYTNSREYSFIHDTLNQCRLDVSCDLQS-LWQFGDTKLVHNEELEKNFTTKR
S

PF12509 // ENSGT00390000006260_0_Domain_0 (122, 279)

EMRESGRHCRELEEHFCFLALPQSDVAQIYQNGISTRA--STLKILGNPLLGIYMFRHV
DIALNYSHSRSITVESILIFKV-LFGKVK------KIQPSVDKNKVSLDPSPNFDCHMSR
NAPSLKDTIE-LQAYSSAVYFYEYSVLSKPVDKPRQCL

ENSGT00390000006260_0_Linker_0_1 (279, 2115)

PYAVVTVKFLGSKVDNGYLMTS
LRFLSTGFPKRAERTCSLNNCTVAKRIGKGKDATVIFEHFKKPVDPF---VQENCLCSVL
NSEINPSNSHISNSYGNVQNG-NISIPETYNGQAEHNLAEIRDTSQVLAHDSDLSLMPSD
AKESV-NGDLLLNWTSLKNILSSLNAAFPLPNNTGSSTVTTSKFIKDPRLMRREESMGEQ
SNTAGLNEILQFEKSLDNVNSEIK---STPSNSASSSEVVPGDCAVLTNCLDAPCFKTCV
NDSQSWAHNTGSEDYDCVPPNKVTMARQCKDQ---G-NFSFPISVSNVVSEVENQNHSEE
KVQRAQQ---------------------------ESG---NAYKKEYNSRISQESQSSDL
KTIYQTGHQMS-AIFPLKKKVS-IDEYLQNTGKMKNF-TDLKDNS--KHEEKQTSWKEID
N-DFTNETKISPMDNYIVLHQE--YKESESHNSFEKSCDKILITQEL-EIPK-SSTSTIK
DKDELDHLALEWQ--IT-SSLESLSQKHPQHSVEYED-NIHTSLAISQKLMELKLGKIN-
ANCASIITEAFPKPKDIPEAKEMLIDTVISSYNIETAHDNSNCSVTRKHVCVHRKNENEP
VSLEDIQRDYKETAYVE---DRGQDHSLFCNSQL-NDIC---LNVNFK-EQRDNYKE---
---SQNEAKE-N-NASSVENNIENIYGDKKQDSHTN--ENFSY-IDEKED-KNYNNIEIL
SSEEFSATFNLICREK-YESAATALLES--EEDTISAMKQKDTE-NTGRSVEHLASTA-F
PEI---ASSSVCVASNAAVQIASATMPVLS-ISNDEHQINQFKETCSSEIPDFGLLVKHR
VSDCEIDKDENKSQESFHQSIN-EN---LVLQSIELESEIEIELEDCDDAFI--FQQDTH
SHENMLCEEFVTSYKALKSRISWEGILALDNGEMEVLESTAGRENSDQHYSKESNYFYSS
TQSSETELPSPILLPDLQIRIT-NIFRPGFSPTVDSLALKDNFCTHVTEATKPEINKE--
----DGEILGFDIYSQPSGENSDYPCEDKVDNI-RQESGPMSKS-EISLSFDLS-HNTDV
---NHRSK-NQNSESLSSEPSNVT-TVDNGSRCFFTKSK-TDYNDTKNKKEVESRISKRK
L-HTPSRDQNI-HEDLRQHKIYGRKRRQTSQDSSECFSSLSQGRIKTFSQSEKHIKSVLN
ILSGEASLCKSKCLSKKLDKAVTHLKKAHRRVHTSLQLITKVGEK-RKGPLPKSYAIICN
NF-WESCDLQDYSSVSQRKY-STKHFLSKRKYDKRRKKRAPKAGISKSLTYVSKHKSYN-
T------SGE--KQCLSRKSMASGVSKSHPT-IHVGEFHNQE-HPESQLPISSTSQSTSQ
S-VYYNSSVSNPSLSEEHQPFSGK-TGCRFSPDHSDEKLFEKENQIDTKFLSSTSKYEKL
EKHSANHNVK---DTTTENSCEANQVINESNSISLSCIKE-NINYGTGN-DYDATCIGCT
KVKTDVLISVLDSNVKHFLN-DLYQQENLTLSDYKRNLEVKW-----TAPIERCEQSIIT
GNFLMDPLNLTLIASKK-YSIPQL-SASAVTDSEGESSKSYLDKQRILTIDSFAAST---
---TIPCCEQSCRGK--ELLKTEQCSSGNCLHTDGNETNVT-ENYELDIAS-VTEESRS-
-YGENI-------V-KLSSSDSSLLLKDNVKGSSSETCIVKKDTEDRIMWKVKQVEKA-K
DSV----YKSSMTE-GSAVNTEYKNQNNQIS-EES-CLNEKIIKTNLIDSHLS-TKNNTT
E-SVSLKNTVSNPL

PF15326 // ENSGT00390000006260_0_Domain_1 (2115, 2382)

NKRE-K-AEIKV-TNDSQS---------------------------
-DLTLHSEIACISK---PGILGVNQTPILPAHSETCKVTTLL-KKPASYMSELKEEHCSA
NHMAFIANLSQILQRADEASSLQILQEETKVCLNILPLFVEAFERKQECSVEQILISREL
LVDQNLWNNCKHTLKPSAVDTLVELQMMMETIQFIENKKRRLEGEPTFRSLLWYDETLYA
ELLGKPRGFQQQSNFYPGFQGRLKYNAFCELQTYHDQLVEL

ENSGT00390000006260_0_Linker_1_2 (2382, 2601)

LEETKREKNSYYVFLKYKR
QVNECEAIMEHCSDCFDFSLSVPFTCGVNFGDSLEDLEILRKSTLKLISACE-DSPKVHS
YPGKQDHLWIIIEMISSKVNFIKNSEAVRIKISLYGLEHIFFDAAKNLVWKEKTQSFSKK
YSQKEDKERLLRVNKCAFSKLQKIYDTLSKDLNNEP-ISPVGLEEDTIIASRKSDHPINK
ATIGIENSKFSS---SLLTY

PF15326 // ENSGT00390000006260_0_Domain_2 (2601, 2722)

PDIYCISEILDQAEFADLKKLQDLILRCTDHLEILKKYFQ
MLQDDNMDNIFITEENVLDVVKNHSHEAILLKPEAIEMYIEIVMVSETIHFLKNSIAKKL
DKQRFRSMLWFDLSLLPELVQCQEKMTSFSFLKDNSTDVCLWKVIESAISELKKDLDIIY
KYDE-AVNRSYAIHLLSRELQELSEIKKLLKNSKYFISTYIDFVPYITSINYGSTMMELE
YNYNQFSTLLKNVMSAPRKDLGKMAHIMKVIKTIEHMKIICAKNAELTISFFLCQMLYNG
RKILQ-LKRKEKMNIHVVKPGENNNKFSISM-MVPPISECINKNISNSSKKRPSTVDKCE
D-SQEQQKNTTISSCKKLKVDMKGVTKINRENATFKHPRTTGSHPQSENKIVSSSSNNLK
RNHL-TSKKVEMQRSLPGSLLPLENPKDTCTSKSESKIDLT-VSSDAPDDFTGQQENL-N
SMRK--RNVNFSAVETKSDEKDCAAFAICDQKSAHG-TFSPDREILLQKFLKNSPDPSQN
SCLSDINPETDVSLVPDA-SVLSKPIFCLVKDIHTDLEMN-DTVFELQDNDIVNSSIKNS
S---CVTSPEPICIQNKIPALQINKLQPAETESEDKYMKNTSNPNTVHTFEASGHITLNV
NQGAEYSLSEQQ--NDKTSKVLTQNAATYWNELPQSACTPTYNSSEHLFG-TSYPYSAWC
VYHYSS--SNGNGITQAYQGITSYELQS---PPSGLLTTVASGQGAQCAQGAHSNLLYSQ
YFTYFAGEPQANGFVPVNGYFQSQIPT-YNFQQPVFSQYASHQPLPQTTYPYLPNRDVPP
EVPWVYAPWH-QESFHPQH--

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--MTYFFIYVSTERACSLNNCTIAKRIGKGKDATVIFEHFRKPVDPF---VQENCPCKAL
NSEMGPFSSDTSSSYGNVQNG-NNSVLEAYNRQTEN-SSNLRDASQVYTHNSGFSFIPTD
NTASG-NGDL-FSVTYLRSILSSISAAFPSHNNTGSSTVITSKLIKDPRLMKREQSMRNK
SSTAGLSDVLPFDKNLSCGDSQIK-LTCMPTSSISSSE-VPADHTI-TSCLNASCFKFSS
ESSHYQAHNSSSKGHDCIASSSIAVTEQFKEQ---H-SSSFPSSLSNALSDVRKQKLSEE
QVQRAQMRSNGPVLTALSSEPRN---------SNE---SENTCSNDSQGHFSQESPSSDI
NSIYKVGHQMS-TIFPAQKKGN-LCEYIQDTGMMRTS-ISTEDST--KDGVNHTWCKETV
---LTNETVKSPIDNSNTLYQE--HKEGGNLNSLSGNCEKIGVTHKL-QMPK-FPISSTG
DKNELYHAALELECSLT-PTIECLSQKYPQHSLEHED-N--TNFAMTQGLIELKTVQNN-
QNFGNILSDAFQEAKDVPLASEKLTDRVISSAAIDISLDSSVCNIIGEYTCVQRENENGE
VSPYNCHKV--EAAHVK---DGVQNHSLSYDAELSCDLN---LKINLQ-EQRD--DE---
---NPNEAKE---------HNTDNINGSEKQDCLAN--DHFTN-IVEMREIKSNTEVEIL
NSEECF-TFNSFRGKN-GKPAETASSET---E----AVEQRHAP-NDQRGLEHLVST--F
PEI---EGSSVCVASNATKQIVGTTVLTVS-TSLGDHQKDELKEICSSESSDLGL-IKHS
ISECEIDTDKDKLQD-FHQLVN-EN---SALK-TGLGSEIEVDLEE-HNASE--FQQNMH
SQGNDLCEEFE-LYESLKSRIDWEGLFGSSYEEIETSSFARR-EGTDQHSSTECNCVSFC
SQ-DKREFYNPIFLPDLQVTIT-NLLSLRISPTDESLELKDNFYKQVTESTEPETNKE--
-----GNASGFGMCSQPSGENSSFSCANKFGNS-VQESGDVSKS-ESSHSSNSS-HNTHV
---DQGSG-KPNNDSLSTEPSNVT-VMNDKSKC-PTKSK-PVFNDTRNKKDMQSRSSKRT
LHASSSRGQNIADKDLREHETHEKKRRPTSHGSSDRFSSLSQGRIKTFSQSEKHIRNVLN
ILNNEASLCKSKHLSRKLNKAVLHLKKAHRRVHTSLQLISKVGQK-RKGPLPKAYAVIHN
NF-WESCDHQGDSLMSERRY--SKHFLSKRKYDRQGDKRFLRFDIEESLTPVSKHRLYR-
T------NRERIAECLSSEVMSGHVSSSLTT-FHVREFCDE-QFPEPQLPLAYTSQSISQ
L-EYTNSIVGN-ESSSELEHFSET-SGNMLD---PKETLTEKEYQTHTQLC--NSDSAKL
KNHTTHS-IR---DIAKEYNSEDKTVLCESNPVYLSFIKEN-TSHNPDK-SYDSTCKAN-
---TDIHVSVLGSKNKPILSVDIYEEDNCVS-DGVKNGEAIFPIEKCTVPMETT--S---
----SIPTED--IASKS-YTIPPV-SSILVTAGEEESSVG---ENGL-------------
------------------------------FDVNENEMNIT-MHSKLDLTS-VTEESKI-
-CKKNM-------K-NLSCNDSSMLLKENVTGP--SKRYMAKYIEEEKIRKIEQAV----
-------YKKIITE-GSPISFKYKSQNKILK-EESFHVNKKIITNNLTDSHLS-TKNSTV
D-TIALKDIPN-QL

PF15326 // ENSGT00390000006260_0_Domain_1 (2115, 2381)

KEKK-EAGQIKV-NNNSHS---------------------------
-D--------CLSR---PAIVETNHRPVLHGNPKVATL-----QKE-------LKEHHSP
NYTSHVTELSQILQRADEAASLQILEEETKLCQNILPLFVQAFERQQECSIDQILISRKL
LVEQNLWNNCRLKLKPCAVDTWVELQMAMETIQFIENKKRFLEGKPTFRSLLWYDESLYS
ELLRRPRGYQLQSNFYPGFQGRLKYNAFCELQNYHNQLVE

ENSGT00390000006260_0_Linker_1_2 (2381, 2604)

FLTETKKEKNSYYALLKYKR
QINECEAIMKHYSDCFDFCLSVPFACGVNFGDSLGDLEALRKSTLKLISVPG-GSPKVHS
YPGKKDHLWIIIEIVSSKVSFIKSNEEISIKVCLYGLEHIYFDAAKSLVWKEKSCSLPKK
HSGK-NRE-MEEINESAFSKLKKIYDVLSKGLNNEP--TSIGLQEDAIIASKQST-LG--
---SILNCRLNK---AWLSYPDI

PF15326 // ENSGT00390000006260_0_Domain_2 (2604, 2722)

SCVGEILDQAKSADLEELQGLTLRCTDHLEILKKYFQ
MLQEDNIDNIFIMEENVLDMLSNHNLGAVILKPEAIEIYIEIVMISETIHYLKNLIAKKL
HNQRFRGMLWFDWSLLPELIGCQEEVVSLSV-GDTQTH-CLWKLVETAISVLKKELAVIY
EYGE-ASNCSYALHLFYRELKELTGVKRLLNNSKYSVSTYIDLVPHTASVNFGNTVAELE
HNYKQFFLLLKNVMSVPQKDFGKMVHIIKVMKTIEHMKVLSAKDTKLSTNLLFLQMLRNK
RNALQ-QNRQEKMETPVTEPGEDSSQPGVSE-QTPPGAECTVKNISDSSKKRPVTADTCE
V-SQGKGNTDTVPSSKKQKVTMKDVG--NRQ-TVSKHPSTTGSPPNDENKIGSNSSDSLK
SIST-SPEVVKRQSSILGSVSPAESVQDTCTPKSESKVEPTDSSPDALASLTEQQENS-N
VIEK--RNGNSSAAETN-DKKDC-PLVTCDQKDIDA-SYSPDHTP-AQESHKTPVDH-TQ
MSPSNLTAGNYDPLVPDT-SLLSVSASQSEKDIY----LS-GTDFHHENNKILNLSTEDY
T---GTSSPEPVCIQDKISVLQVDKTQPIKSESPKNCMTDAPNPNTA-PFGSYGNSALNM
NGTVQHTHSEQ------NSKVLTQKVGTSRNIPPQSACSPVYNSSERSFG-TSYPYYSWC
FYQYSS--SNGTAVTHTYQGMTAYEIQQP--PPPPMLTTVAS-----TVQSTHFNRSYSE
HFSYFAGQPQANSFNPGNGYFPSRTPVSYNYQQPVYSQFASHQPVPQATYPYPPNPGVPP
QVPWTYAPWQ-QNPFLRRP--

--------MTSIKMEMNENDKYRSP---------DGESLWTTDTDASSGKKFTIPKIRRT
TEKVYLSSCYTNTREYGVIHGTLRQCRLDVSCDPQL-TCQFGDTRLVRNEYLEKQFAAKR
S

PF12509 // ENSGT00390000006260_0_Domain_0 (122, 279)

EMRESGRNSRELEEHFCFLALPQSSVVDIYQNALSVGT--SALRVLGNPLLGVYLFRHV
DVALRYTLSRSSTVESIMVFKV-LFGRVK------KIQPSVDKNKVSLDPSPNFDCHMSR
NMPSLKDSIE-LQAYNSMVYFYEYDLFSRPVDKPRQCL

ENSGT00390000006260_0_Linker_0_1 (279, 2115)

PYAIVTVKCVGQKAGNGQLMTS
LRFPSTGFPKRLERACSLNNCTIAKRIGKGKDATVIFEHFRKPVDPF---AQENCPCKAL
NSEMGPPSSDTPNSYGNAQNG-NSFWLEPYNREREN-SSQLRDGSQVYTHNSGFSFIPTD
NTASG-NDDL-FSVTYLRSILSSISATFPSHNNTVSSTVITSKLIKDPRLMKREQSMKNQ
NNTTGLSDVLPFDKSLGPGDSQM--LTCVPASSVSSCE-VQADHTI-TNCLDASCFKFSS
ERSHCQTHSIGSQAYDCIASKRTAITEQFKEQ---H-SSSFPGSLSNALSDVGKQEHSEE
QAQRTQMRSNIPVLTALSNEPQN---------SYESEKSELTCSKDSRGHFSQESS--NT
DTIYKVDHQMS-TVFPVQKEGN-LCEYVQERRVMRTF-ISPEDGS--KDGVEQTWSKETV
---FTNEAISGTIDNSKTLYQE--HKEGGNLNSLSGNCEKIAVTYKL-QMPK-LPMSSTG
DNSELDRAASELEHSLI-PNVECPSQKCAQHSLEHED-N--TKFAMAQGLIELKT-----
QNFGNILSDEFQEAKAVPLAREKLMDRGSPSSAIDISLDSSVRNMLGEYRCIQRGNENVT
VSPFNCHKA--AAPHVN---DNVQDHSLSYDAELSCDLN---LKINLQ-EQRD--DE---
---NPREAKEKEDAALSPEHSTDSMNGSEKPDFHAN--GLFTS-IVEMRGIRSNTKIEIV
NSEDCF-TLHSFWGKK-GKAAETASSGS---E----GVGKRHAP-GDERHREHLVSA--L
PST---GGSSVCVASNATKQVVGTTVLTVS-TNHGHHQKDQLKDTCSSETSDLGL-VKHS
ISECEIDADKDKLQD-FDQLMN-EN---SALKDYGLGSEIEIDLEEHDNASL--FQQNMH
SHENDLCEECD-FYESLKSRIDWQGLFGKSYEEMETSSSARREEGAGQLCSTECNYVSFY
SQKDKKGLHNPIFLPNLQVTIT-NLRSLRISPTDESLEPKDNFYRHITESTEPETNKE--
-----GNASGFSICSQPSGENSSFSCENKFSNS-VQESGNTSKS-GITHSSNSS-HNTPV
---DQGSG-KPNSDSLSIDPSNIT-VMNDKSKY-PTKSK-PDFSDARNKKDMKSRSSRRN
MHAS-SRGQNIAHKDLRDRETHERRRKPTSHDSSDRFSSLSQGRIKTFSQSERHIRNVLN
ILNSEASLCKSKHLSRKLNKAVLHLKKAHRRVHTSLQLISKVGQK-RKGPLPKAYAIIRN
NF-WESCDLQGDSLMSERRY--SKHVLSKRKYDKQGEKKFLRFDIEESLTPVSKHRSYR-
T------SRERVAECLSSEIMSGHASSSLTA-FHVREFCDEEQLPESQLPLAYTSQSISQ
S-EHTNSILGN-AGSSELEHFSKT-SGNILD---PEETLTEKDYQTDTQLC--NSDSAKL
ENHSTHS-IR---NIAKEYNSEGKTGVCESNSVSLSFIKEK-TSHSPDN-SRGATCKAN-
---SDTHLSVLDANKNHILSVDIYEQDNRVY-DGAKNGEAIFPTEKCSVPMETT--S---
----SIPTES--LASRS-YAVPPV-PSVLTTAGEEESSVG---ENEL-------------
------------------------------FDIDKSEIIIT-KRSKLDLTS-VTEGSDN-
-YKKNM-------N-ALSSSDNVVLLKQNVIGP--SKGYMAKYIEEEKIRKIEQAV----
-------YKKIITE-GSAISFKYKSQNKLLK-EESFPVNKKMMTNNLTDSHLS-TKNPTV
G-TVASQTIPN-QR

PF15326 // ENSGT00390000006260_0_Domain_1 (2115, 2381)

KERM-EAGQIKV-SDSSRS---------------------------
-D--------CLSQ---PAMGESSHRPALCENSKAAAL-----KKE-------L-EHRSA
NYTSHVTELPQILQRADEAASLQILEEETKLCQNILPLFVKAFERQQECSVDQILISRKL
LVEQNLWNNCRLKLKPCAVDAWVELQMAMETIQFIENKKRFLEGKPTFRSLLWYDESLYS
ELLHRPRGYQLQSNFYPGFQGRLKYNAFCELQNYHNQLVE

ENSGT00390000006260_0_Linker_1_2 (2381, 2605)

FLTETKKENNSYYAFLKYKR
QINECEAIMKHYSDCFDFCLSVPFACGVNFGDSLGDLETLRKSTLKLISVHG-GSPKVHS
YPGKNDHLWIIIEIVSSKVSFIKSNEEINIKICLYGLEHIYFDAAKSLVWKEKSCSLLKA
HSEK-TRE-AEEINECAFSKLKKIYGVLSKGLNSEP--TGIGLEEDAMIASTQSA-LG--
---SIPNCRLNK---AWLSYPDIS

PF15326 // ENSGT00390000006260_0_Domain_2 (2605, 2724)

CVGDILDQAKSADLEKLQDLTLRCSDHLEILKKYFQ
MLQEDNIDNIFIMEENVSDMLNNHSPEAVILKPEAIEIYIEIVMVSETIHYLKNSIAKKL
HNQRFRGMLWFDWSLLPELIGGQKEVASFSV-GDNQTH-GLWKLIETAISVLKKELAIIY
EYGE-ASNCSYALHLFYRELKELTGVKRLLSNAKYSVSTYIDLVPHTASVNFGNTAAELE
QNYKQFFLLLKNVMSVPQKDFGKMVHIMKVMKTIEHMKVLNAKDTKLSTRLLFLQMLRNR
RNALQ-QNGKGRKETSVTEPEEDSSQPAASE-QTAPAAERTMKSISASSKKRPVTSDTCE
V-SQEEGDTDAVSSWKKQKVTVKDDG--NSQ-TISKHPSTAGAPPDNEDRTGSDSSDTLT
GFSA-SPEVVKRRN----SVSPAESVQDTCTPKSASDVEPTDSSPDASASLTAQQEDS-D
GIKE--GNVGFSAAETN-NKEDC-PLVTCDQKDIHS-SSSPDHTP-AQKSHNTAVDH-TQ
IAPSNLTAGNDDPLVPDA-SLLSVSAPQAVKDIHSSPEMS-DTDSQRENSEIVDLSTEDR
T---CTSSPELVCIQDKTPDLQVDKTQPIKSESPEKCAMDAPNPSAA-PFGSYGSSAINV
NGTVQHTHSEW------NPKVLTQKFGTSRNRPPQPASPTVYNSSEHSFG-ASYPSYSWC
FYQYSS--SNGTAVTHTYQGVTAYEMQ----PPPPMLTPGAS-----TVQGTHVNHSYSE
HFSYASGQPQANSFIPGNGYYPSQAPVSYNYQQPVYSQFASHQPVPQAAYPYPPNPGAPP
--PWTYAPWQ-QDPFPRRH--

-------------MEMKEISKHKALWKMSST----KEPLPITGIEASPLKKFTIPKIRRT
AGKVYLSPCCTNTREYSFIHETLNQCRLDVSCDLQS-SWQFGDTKLVHNEELEKNFTTKR
S

PF12509 // ENSGT00390000006260_0_Domain_0 (122, 279)

EMRESGRHGRELEEHFCILALPHKDGIEIYQNGLSTKT--STLKILGNPLLGIYIFRHV
DIALNYAHSRSITVESIIIFKV-LFGKVK------KIQPSMDINKVCLDPSPNFDCHMSR
NVPSLKDTIE-LQAYNSVVYFYEYSVFSTPVDKPRQCL

ENSGT00390000006260_0_Linker_0_1 (279, 2114)

PYAIVTVKFIGQKVDNGHLTTS
SRLLTTGFSKRPERTCSLNNCTVAKRIGKGKDATVIFEHFRKPVDPF---APENCSCNTQ
NSEINSCNANISNSYENVQNG-NISILETFSGKTENSSAETRGISQEHVHDPG-PLMPSD
NKESGNNGC--LFSTYLKDILNLMSASFPPHNNTDSSTVITSKFIKDPRLMKREESMEKQ
NNTVGFSEILPSEKNLDD-NSC------VPTNSASSSEVVPHDCAALSDCLDTPCSRFSF
DDSSSQTHNMDPKDYHCIPPNQITRVRQSKDQ---G-HFSFPVSLLNV-SELENQKHTEE
KAQTAQERSDIPLLIKQNNKAQS---------TYESV---NTYTKDSDSHISKELHSSNF
KTIYQIGHQMS-TVFPLQRKET-IDECIQNIGKIRNF-TDPEDSY--QYEEKQTLQKETD
D-NFTDETKIIPINNYTS-CQE--YKDDETLDSLGENSDEVLITKEL-EMPE-SLASTKE
DKSEQDHLALKLESNLT-LNIECLSQKH-QHSMDYED-STHTSFVFTQKLREMNLEKA--
NKCISIITDPFQEAKDIPQTRE------TSFHGIEIALDNSNCSITREYVCVQRKNENEP
V-SDDIQRNHKETPYIE---DKDQTHILSSNTQLNDDKY---LNTHFK-GQGDNDKE---
---NKNK--END-RTSFPENKIEKIYGRKKQEYHTN--NTFSN-IVDGRKNKNDNKVEIL
ISEDIATTFNLIWGEK-GMSPETSLLED---KDILAAKKQRDVP-NIGRSVEHLALTT-F
PEI---ADSSVGVVSNPMIELANTTLPALS-ANREAHQRYQFKETCSSESPDFELLVKHK
TADCEIDLDKNKLQDSFHQPMN-EN---S-LQNFELGTEIEVELEEYDDAFL--FQQNRH
SHGNVLDEEFEASYEALKSRIDWEGLFGSNNGKMDNLGST-TRENIDHQRSKNTICFCPS
TYKK---EVYPILFPDLQVRIT-NTFTPTFSPPDDTLSVKDNFYKCLTEASTPGINEG--
------EAPGFKIYSKSFCENSGYPCANQFDNS-MQDSGLLSKS-DISHSSDLS-HSTDV
---NDMSG-KK-NDTFSVEPSNIT-TINGDHRCFFTKSK-TDFNDTRNKKKMESRISKKY
I-RASFREQNISHKDLRQREMCEEE-RLTSHDSSECFSSLSQGRMKTFSQSERHIRDVLD
ILNSEASLCKSKRLSRKLNRAVLHLKKAHRRVHTSLQLIAKVGEK-RKGPLPKAYEITCN
NF-WESCDLQGYSSVSERKY--SKHLLSKRKYDKRGE-KVFGFDVNQS-ACVSKHKSYK-
T------NGERIAMCHSKRSVTSSDSKSHST-VCIREFCNQH--SESQLSLFSISQSTSQ
P-EYNN-SIHD-SRSSKLKPFSGK-TEYLLY---SDEKQSEKENQIDMK-LSNISKCEKL
ADHAAHNKDV------AKKNSKVNKIKSKSRSICLSGTKENNVSYSTDK-N-DATYIPHT
QVKTDIFISILDSNMKSFLNVDTYKRDNCIISGCQSNLKVNFPIERWTPSTESYKASIIT
GKFLMGPFSLTLISSKK-YNILQL-STTPVTDSERESSKSCLNKQRILAVDSSATPT---
---TMSHCQQIHGGK--KLLKTQ-SS--SSLHIEGNETSVT-EHSELDLTS-LTRENKS-
-YGENI-------MKR-SFKDSSLLLKDNIKDL-SKKNDAKKDTWNRKIRKNEQAEKA-E
DSL----YQKSMTE-GSIVKIEYKNQKNKTLKEKSPHLNMKTVQSDLIDSHLS-IKTTPE
A--VSLNNTVSSQ

PF15326 // ENSGT00390000006260_0_Domain_1 (2114, 2382)

LNKRK-RKGKRKV-SNDCQS---------------------------
-G--------YISK---PGILEIDHRPILHAHSETSEV-TIQ--KPTSYENELKENHCSV
TQTALVTELSQILQRADEASSLEILEKETKTCQNILPLFVEAFERKQECSLEQILISREL
LVEQNLWKNCKYKLKPCAIDTLVELQMVMETIQFIENKKRLLEGEPTFRSLLWYDETLYS
ELLGRPHGYQLQSSFYPAFQGRLKYNAFCELQNYHNQLIEL

ENSGT00390000006260_0_Linker_1_2 (2382, 2542)

FTETKRENNSYYAFLKYRR
QINECEAIMKHCSDCFDFSLSVPFTCGVNFGDSLGDLEVLRKSTLKLISIYG-DTPTVHS
YPGKQDHLWIIIEVISSKVNFIKNNEAVGIKVSLYGLEHICFDAAKNLVWKEKRQSICKK
YSQK-NKEVIHKMNKCALSKL

PF15326 // ENSGT00390000006260_0_Domain_2 (2542, 2721)

QKIYDTLSENLNKEP-ASNIELKEDTVITSRKSDNLT--
---TVENFRL-S---TLFLQPDICCIGEILDQAEFADLKKLQDLTLVCTDHLETLKKYFQ
MLQEDNIDDIFITEENVLDMLKNHNHGAVILKPEATETYIEISMLSETVHFLKNSMAKKL
DNQRFRGMLWFDLSLLPELVHCQEKMVCFSFLEDNPRD-CLWKAVETGISDCKKDLDVIY
KYSE-AVNCSYALHLFSRELKELSEIKKLLKKSEYPISTYIDFVPYVISINYGNTVTELE
QNYSRFSTLLKNIMSVPQKDLGKIAHIMKVMKTIEHMKIICAKNAKLTTSFILCQILHNK
RNNFQ-LKRKEKMNIHFTIPEENI-RPNTSA-KVPSTSVNLIKNISHSSKRRPNAVDTGE
D-SQEKEKN-TISSCKKRKLNMNYISKINREKAVFRCLRTTGFHPKGENKIGSSSSDNLK
RNYV-SPKRDEMQRSLSASLSPLKNLQGTCTSESESKIDLTNSSSNTSEHHIGQQENL-N
NIKK--RNVNFGAPETKSYKKDCASFATCDLKSING-TLSKDQEIPSQKLLKNLPDPAQK
THLSNLKPATNDSLVPNSSSLFSEPISLSVRDIHTNLEIN-GIVLEHQDNELLDSSINKS
T---GASFPEPIHTHSRYP--------------------DTLSPSPI-PFGASGNLTPDV
NQTAEYSFSQQQ--DEENSKVLTQKAATYWNELPQSACTPVYNSSDHSLQ---TPYYSWC
IYHYSS--SNGNATTHTYQRITSYEGQS---PPSGILTTLTS-----TVQNTHSNLLYSG
YLSYFADQPQANAFVPVNGYFQSQMPISYHFQQPIVSQYASHQPLPQAVYPYPPAPGVLP
EAPWIYAPWQ-QEPFQPRH--

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----YFSYISTERTCALSNCTVAKRIGKGKDATVIFEHFRKPLNPY---VQENCSCSTP
DSERDSYNSYMSNTNGNMQNG-NFPVLETHSGWRDNCSAEIRDPSQVPENNSDHSFMPHD
NRE----IDVLFNLPYLKSILSNISAAYSSHNNTCSSTVITSKLIKDPRLIRREQNMGKK
NNSTVLSDISPPDNHVDHVNSGIN-LSSLPTNSRTSSAVVPGDHAVLTNHFDASCFQVAF
EDTQFQTHNMGSKDYDCIASNEITTTGQCKEQ---C-NFALPISLSNVVSEVENQKHSEG
KAQSFQKRNNFPFLTKQSREPPN---------SKESV---DTCRKDSKSHISRKSQCSNL
KPVNKVGHQVS-IMSPLQKKGN-IDEYIENTGMLRTP-IGTEDNS--KCGANQNWWKESN
T-YLNIETKIVPVNNCNILHQE--YKEGRNLNSVGGNCDKRRMSEEL-QVAK-SNIPAAK
DKDERDHIAVASGCNLT-SNVECFSQKDPQCSLEYED-TIHTSFATSQKLMELKN-----
QNCVNIVYDASQEAEGIPQAKEVLIDKSLSEGEGTPSLDNSNCNISREYMCVKRKNKNEP
LSLESIQKDYKETLHPG---DEDSDPSLFYSSKLNINNT------NFKGQKED--KE---
---NPNEAKEED-------------NRHEKHDFHMD--NMVTN-IVETGESRNYNTVEIL
SSEGSS-KFNLFGEEK-DIPTDS-----------VTAIKQRSAQ--NGGSVQHLAST--V
PEF---AGVSVEGASNSTDKVSSTTKPTLS-TDHETDQRCFLKDTCPSGNSHFSL-IKHR
VSDYEINMDKNKFQYSFYPSVN-EN---SSLENVELANEAEIQ---CDDALL--WPRDTC
SHENVLDEEFE-LYEVLKSRIDWEGLFGGSNEEREPLGSSPKGQNNEQHSTAEANCVYSF
AQKNKRELLNSILLPDLQVTVI-DGPGSGFSLNDESFALT-DFYKSITESSKPEIN-E--
-----GKASGLGFFSQPSGENSGFSCEDKLDNS-VQEPGLVSKS-EIFHSSDFS-HNIHE
---NNTSE-KLSCESLTANLSAAT-V-TNESKCSSTKPK-TDFSDARNEKDKR------R
LLI-CPKDQTMSHKDIKEYENSERRRKVTSRDSCEWFSSLSQGRMKTFSQSERHIRSVLN
ILNSEASLCKSKRLSKKLDRAVLHLKKAHRRVNTSLQIISNVGKK-RKSPLPKAYAITCN
NF-WESCDLQGS--VSERRY--SRHALSKTKYGEQGEKRLLRFDIDERLGQVSKHKSYR-
T------NPERIAECLPSEIVSGSVSQSLTT-THVKH-CD-EQHPESQLPLTYICQKRRQ
S-EENNSTVRN-ANSLAPEHSSEA-RECMLY---PDETLTEKEYHTDSELV--NSANVKL
ENHSTYN-SK---DVAKENNSEPNAVIHESNLASLSCIKDNRSP--NTD-NCDASGKAD-
---SDMLVSKVDFSAKHFLNANVYKQDNLRPPGCKRNQVITFPIEECTIAISTL--SIPK
GNILTDPLSL--TASKI-YSIPPL-SSTLLSGDEEESSESSV--GHT-------------
------------------------------FHVNGNEIRPR-KHSKLDLTS-VTEESKS-
-CKKNI-------TEKLFSNGCSLLFKDNLKYS--SKRLTTKDIHKRKIKKTEQAV----
-------YPKSTSA-GAIVNIKYKSQEEEIL-KEFFHLTKKTNENNVIDTYLS-TKNATL
E-TITLKNMLFSHLS

PF15326 // ENSGT00390000006260_0_Domain_1 (2116, 2381)

KRK-KMEK-KV-SSNSLC---------------------------
-D--------SISK---TA----------------------------IIRTGPAKKHCLA
NCVSPIAELSQILQRADESSSLQILGEETKICQNILPLFVEAFERKQECSLEQILISREL
LVEQNLWNNCNRKLKPCAIDTLVELQIVMETIQFIENKKRYLKGEPTFRSLLWYDETLYD
ELLGRPRGYQMQPNFYPAFQGRLKYNALCELQNYHSQLVK

ENSGT00390000006260_0_Linker_1_2 (2381, 2603)

CFAETKKE-NSYYALLKYKR
QINECKAIMKHSSDCFDFCLSVPFTCGVNFGDTLEDLETIRKSILKLITAYE-DSLKIQS
LPGKKDHLWIIIELISSKVNFIKTNEEISIKISLYGLEHICFDAAKHLVWKEKSYSFLKN
SQKK-NQEMLVTVNKCAFSRLQKIYDTLIRDLNNVT-TSNIELEEDTLIASRQSDDPV--
---SIENYGFPS---TLLSQPD

PF15326 // ENSGT00390000006260_0_Domain_2 (2603, 2721)

ICCVSEILDQAEFADVQKLQELTLRCTEHLEVLKKCFQ
KLQDDDIDDIFVTEENVLDVLSNQQHGAVILKPAAVETYIDVVMLSETVHFLKNSMAKKL
NTQTFRGLLWFDLSLLPELTHCQEQMASFSL-NDNP-A-CLWKVIESTVSELKKELDAIY
GCNE-AVNCSYALHLFSRELEELSEIKNLVKNSECSISTYIDFVPYIASINYGNTVAELE
HNYNQFAMLLKTMLSFPQKDLGKMAHVMKVMKTIKHMKIINAKSANLSTYFILYQMLHNK
-NTSQ-LEKKEKMNIHVTKPEENSSKPSTST-QVSSISECISKTTSDSSKKRPIAADEGE
EDSWENENTTT-------------------------------------ISIASSSSDDLE
RNCL-SPKMAERRSSFPGLPLSFKNLQDACTSKSDSKMDLGNSSPDIIGSCTQQQENL-N
SIKK--TKVSFSAAEIN-ENKDC-PETYH-LKCGDG-TFLEDYKTPSQKLRESPPGYTQK
TCLSNTKTRIDQCLEPDA-AGFSVPTFHSAGAIRPNLEMS-STDFEHQDNEIIDLSVKAD
T---GTNCPEPLCVQDKILVLQANKTPFIKTEAQGKYEEESLNPSMA-PCSSSESSTL--
---------VKG---EENPKVLPHRPDTCWREPPQPAYVPVSH-SEQQFG-ASYPSSAWC
VYHYNS--SSGSTVTHTYQGTTSHERQ----SPPGTVTAVAS-----TVQSTHSHLLYSE
YFRYCPAQPQVNAFIPGNSYFPSQMPIPYNFQQPIFSQFAFHQPLPQAAYPYPPNPGVFP
EVPWIYGEL------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------IPSD
TRESV-NNGDLLNLTQLKDILSGLAAAFPVHNNIGSSTVVTSKLIKDPRLMKREESMGKH
NTVTGLNEILPLEKSLDFDNSEIN-LSSLPANSASSSEVMPGDDTVLTNYLDVPCCSSSF
DDSQTQGLNLSSKTYDYTASNKITMTEQYKSQ---D-NFSFTKCVPNVVSEVEIQKHGKE
KPQG-SR---------------------------KRI---NTCTKGYSH-ISPESQSSNF
NTMYQTAHQMS-TVFPLQSKES-VREYIQNSGNMRNF-TGPESDT--KHEEKQNFWKESD
N-SFTNKTRVSQVDNYISLHQD--YKKDKSLHYLGGNCDQTLITQEL-EKPK-SSASNLE
NKYELDHLALEVEDNHA-SGVESLPQKRPRHSYVYED-NIHTGFSISQKLTELTLEKPD-
QNCVSIMTDAFQEAKDIPQARQLPAD--TSSHDIKIAHDNANCSIPKEHIYVPKRNENYP
VSLENIQTDCKETPQIN---SKYQVHTQFCNTHMNNDVQ---ME----------------
-----------G-VASSTENNIENIYGDEKKTFHTN--KNFTN-TEERRENKNYSSMEIL
SSKEFSATFNLTWGTK-YVSTESALLEN---EDTVSAVGEKDLH-NPGRTIEHLVSTT-F
PKS---SVSSVHVSPHTALQVAGTTVPALG-TNCDIHHRYQCKETCSSQSPDFDLLLKHK
VSDHEMDMDKNQLHNSFHQSVS-DT---SIPQSFKVDNEIEIESEQNDDAFL--FQQDTH
NHGNVLYEELGASYEALKSRIDWEGLLGSKNGEVEVVEN--VRENIDQHCSEESNCFYSS
TQKNEAELFNSILLPDLQIKIA-NVFMQGFSPTVESLALKDNFCKCINEATKSETNKE--
----EGEALGFKIHSQCSGENSDHPSEGEFGNV-REESGLVSKS-EISLSFDLS-HNTHM
---NHMSEEKKNSGPLLTEPSNVT-TVNNESRYSLTKSK-ADCNDTRNKNNTESRISKRK
P-YTPFRDQNMPHKDLRHHEICGKK-RLTRQDSSECFSSLSQGRIKTFSQSEKHIRSVLE
ILNSEASLCKSRRLSRKLDRAVLHLKKAHRRVHTSLQLIAKVGEK-RKGPLPKAYAIICN
NF-WESCDLHGYSSVSERRYYSTKHFCQKENM-----IKVLRFEVNESLTHISKHKSYK-
T------SGEKIAKCLSKKNVSS-VSRSHTT-ILMREFCDQA-YPESQLALCSPSQSTSQ
L-ADSESTVRN-PRSSELQPFSGK-TECLFSSDCPDEKLTEKENQSD-TKLSNMGKYENL
ENHSACSNIK---DTTKENISEANEVINKRNSLSLNCIKENNVSFSMNK-NYDATCIGHT
KTKTHIVISVLESSVKRFFNLDIYKPDNLILCD-KRNLEVNFPMESWTAPNERSKSGITT
GNFLMDPLNLTLITSRKCNSIPQLLSTTLVTDSEKESSKSYLDKQSTFAVDSSAAST---
---TAPHCQQRCGGK--ELLNTEQCSSNNCSHIDENETNVI-DSSKLDFTP-VSEESKS-
-YGENM-------MKKLSSSDSSLLLKYNMKGSSSKKCIAKKDIEDRKIGEDKQAEKT-E
YSV----H-KNMTE-GSAVKIEYKNQKNKVL-EDSSYLIAKTIKNNLTDSHLS-IKNATE
A--VSMNNMVSNQ

PF15326 // ENSGT00390000006260_0_Domain_1 (2114, 2382)

LKKRE-KEEGIKV-SHDSQS---------------------------
-DSTLHPEIACHSK---PDVIGMNHMPLSHAYSETFKASTPQ-RKPTSYMNELKEKHCSA
NRSALIARLAQILRRADEASSLQILQEETKVCQTILPLFVKAFERKQECSFEQILISRDL
LVEQNLWNNCRHKLKPCAIDSLVELQMMMETIQFIENKKRLLGGEPTFRSLLWYDETLYS
ELLGRPRGFQQQSNFYPAFQGRLKYNAFCELQDYHDQLIEL

ENSGT00390000006260_0_Linker_1_2 (2382, 2600)

FEKTKRENNLYYAFLKYKR
QINECEAIMKHCSDCFDFSLSVPFACGVNFGDSLGDLEAIRKTTLKLISMYG-DSPLINS
YPGKQDHLWIIIEMISSKVNFIKSSEAVSIKISLYGLEHIFFDAAKSLIWKEKRQSFCKK
YSGKKNKEILLKMNQHAFSKLQKIYDTLSKDLSSEQ-ISSIGLEKNTMIASRKSNALVNK
TTVS---SRFNS---TLLS

PF15326 // ENSGT00390000006260_0_Domain_2 (2600, 2722)

HPDICCISEILDQAEFADLKKLQELTLRCTSHLDILKKYFQ
LLQEDNVDNIFITEDNVLDMVKNHSHEAVILKPAAIEIYIEIVMLSETVHFLKNSMAKKL
DKQRFRGMLWFDLSLLPELVQCQEKMSSFSFLKSNSTD-CLWKVIETAISELNKDLDIIY
KYNE-AVNCSYALHLLSRELEELSEIKKLLKKSKYSISTYVDFVPCIASINYGSTVTDLE
HNYNQFSTLLKNIMAAPRKDLGKMAHIMKVMKTIEHMKMICVKNTKLTISFILCQMLHNR
KKTIE-PKRGEKMNAHV-EPRKSI-KSSTCV-KVSSISECIMDNTSNSSKKRPITLEKYE
D-SQEQEKNTTVSSCKKQKVNMKDVTKINRGKATFKHPRTTRSHPKSENEIGPGSSDSL-
RNHV-SPKKVEIQRSLPGSLLPLKNLKDTCTLKSEGKTGLT---------------NL-N
SMKK--RNVNVSAAETKSDKKDCSPLAISDQKSVDG-TFSKDSETPSQKF-KNSPDPAEK
SCSSDLKPGADATLLPDGPSVLAKPIFHFVKDIHANLEIN-VTDFELQDNEMLNSTIKNS
T---CASSPEPTLTQNKIPVPQVNKTQLAKTESKEKYMKDTWNPNTL-AVETFENMTLNV
DQTVDYSFSEPQIQKSENSNVLTQNASTYWNEHPQSACTPVYHSSEHSFG-TSYPYYAWY
VYHYSSS-SNGSSITQTYQGITSYGAQP---PPPGMLTAIAS-----TVENTYSNILYSQ
YFSYCAGEPQANDFVPVNGYFHSQMPV-YSCQQPVFSQYVSHQPVPQTAYPYSPDSGVLP
EVPWAYVPWQ-QEPFQRGH--

---------MANKMEMKETAKQDTLWQMSST----SKPVLNTR-EVNPLKKFTIPKIRRT
AEKVYLSPCYTNSREYSFIHDTLNQCRLDVSCDLQS-LWQFGDTKLVHNEELEKNFTAKR
S

PF12509 // ENSGT00390000006260_0_Domain_0 (122, 279)

EMRESGRHCRELEEQFCFLALPQSDVAQIYQNGISTRA--STLKILGNPLLGIYMFRHV
DIALNYSHSQSITVESILIFKV-LFGKVK------KIQPSVDKNKVSLDPSPNFDCHMSR
NAPSLKDTIE-LQAYSSAVYFYEYSVLSKPVDKPRQCL

ENSGT00390000006260_0_Linker_0_1 (279, 2115)

PYAVVTVKFLGSKVDNGRLMTS
LRFLSTGFPKRAERTCSLNNCTVAKRIGKGKDATVTFVRFKKPVDPF---VQENCLCNAL
NSEINPFISNISNAYGNVQNG-NISIPETYSGQTEHNLAEIRDTSQVLAHDSDISLMPSD
AKDSV-NGDLLLNWTSLKNILSGLNASFPLHNNTGSSTVTTSKSIKDPRLMRREESMGEQ
SSTAGLNEILQFEKSSDNVNSEIK---STPSNSASSSEVVPGDRAVLTNGLDTPCFKNSV
NDSQSWAHNMGSEDYDCIPPNKVTMAGQCKDQ---G-NFSFPISVSNVVSEVENQNHSEE
KAQRAQQ---------------------------ESG---NAYTKEYSSHIFQDSQSSDL
KTIYQTGCQTS-TVFPLKKKVS-IDEYLQNTGKMKNF-ADLEDSS--KHEEKQTSWKEID
N-DFTNETKISPID--IVLHQE--YKERESHNSFGKSCDKILITQEL-EITK-SSTSTIK
DKDELDHLALEWQ--IT-PSFESLSQKHPQHSVEYEG-NIHTSLAIAQKLMELKLGKIN-
QNYASIITEAFPKPKDIPQAKEMFIDTVISSYNIETAHDSSNCSITREHICVHRKNENEP
VSLENIQRDYKETAYVE---DRGQDHNLFCNSQLSNDIC---LNVNFK-KQTD--KE---
---NQNEAKE-N-SASCVENNTENIYGDKKQDSHTN--ENFSN-IDEKED-KSYHNIEIL
SSEEFSTTFNLICRENNAVSAATALLES--EEDTISAVKQKDTE-NTGRSVEHLASTT-F
PKT---ASSSVCVASNAAIQIASATLPALS-LNNDDHQIYQFKETCSSESPDFGLLVKHR
VSDCEIDTDKNKSQESFHQSIN-EN---LVLQSIELESEIEIELEDCDDAFI--FQQDTH
SHENMLCEEFVTSYKALKSRISWEGLLALDNGEMEVLESTTGRENSDQHYSKESNYFYSS
TQNNETELTSPILLPDLQIKIT-NIFRPGFSPTADSLALKDSFCTHVTEATKPEINKE--
----DGEILGFDIYSQPFGENAEYPCEDKVDNI-RQESGPVSNS-EISLSFDLS-RNTDV
---NHTSE-NQNSESLFTEPSNVT-TIDDGSRCFFTKSK-PDYNDTKNKKEVESRISKRK
L-HTSSRDQNIPHKDLRRHKIYGRKRRLTSQDSSECFSSLSQGRIKTFSQSEKHIKSVLN
ILSDEASLCKSKCLSRKLDKAVVHLKKAHRRVHTSLQLITKVGEE-RKGPLPKSYAIICN
NF-WESCDLQGYSSVSQRKYYSTKHFLSKRKYDKRRKNRAPKADISKSLTHVSKHKSYK-
T------SGE--KKCLSRKSMASSVSKSHPT-SHMGEFCNQE-HPESQLPVSSTSQSTSQ
S-VYYNSSVSNPSLSEEHQPFSGK-TGYLFSPDHSDEKLIEKENQIDTEFLSSTSKYEKL
EKHSANHNVK---DATKENSCEANEVINESNSVSLSCIKE-NINSSTGN-DCDATCIGHT
KAKTDVLISVLDSNVKHFLN-DLYQQGNLILSDCKRNLEVKW-----TDPIERPKQSIIT
GNFLMGPLNLTLIASKK-YSIPQL-SAAAVTDSEGESSKSYLDKQRILTVDSFAASS---
---TVPHCEQSCREK--ELLKTEQCSSGNCLHTDGNETNVT-ENYELDVAS-GTEENKS-
-YGENI-------V-ELSSSDSSLLLKDNVKGSSSETCIVKKDTEDRITWKVKQVEKA-K
DSV----YKRSMTE-GSTVNTEYKNQKNQIS-EES-CLNEKIITTNLIDSHLS-AKNTTT
E-SVPLKNTVSNPL

PF15326 // ENSGT00390000006260_0_Domain_1 (2115, 2382)

NKRE-KKGEIKV-SKDSQS---------------------------
-DLTLHSEIAYISK---PGILGVNHTPILPAHSETCKVPTVL-KKPASYVSEFKEKHCSA
NHTALIANLSQILQRADEASSLQILQEETKVCLNILPLFVEAFERKQECSVEQILISREL
LVDQNLWNNCKHTLKPCAVDTLVELQMMMETIQFIENKKRHLEGEPTFRSLLWYDETLYA
ELLGKPRGFQQQSNFYPGFQGRLKYNAFCELQTYHDQLVEL

ENSGT00390000006260_0_Linker_1_2 (2382, 2544)

LEETKREKNSYYVFLKYKR
QVNECEAIMEHCSDCFDFSLSVPFTCGVNFGDSLEDLEILRKSTLKLISVCG-DSPKVHS
YPGKQDHLWIIIEMISSKVNFIKNNEAVRVKISLYGLEHIFFDAAKNLVWKERTQSFNKK
YSQKKDEERLLRVNKCAFSKLQK

PF15326 // ENSGT00390000006260_0_Domain_2 (2544, 2722)

IYDTLSKDLNNEP-ISPIALEEDTIIASRKSDHPINE
ATISIENSKFNS---NLLAHPDICCISEILDQAEFADLKKLQDLTLRCTDHLEILKKYFQ
MLQDNNMDNIFITEENVLDMVINHSHEAIILKPEAIEMYIEIVMVSETIHFLKNSIAKKL
DKQRFRGMLWFDLSLLPELVQCQEKMASFSFLKDNSTDVCLWKVIETAISELKKDLDIIC
KYNE-AVNCSYAIHLLSRELQELSEIKKLLKKSKYFISTYIDFVPYIASINYGSTVTELE
YNYNQFSTLLKNVMSAPRKDLGKMAHIRKVMKTIEHMKIICTKNAELTISFFLCQMLYNR
RKILQ-LKRKEKMNIHIVKPGENNNKFSIST-MLPPVSECINKNISNSSKKRPSTVDKCE
D-SQEQQQDTTISSCKKLKVDMKDVTKINREKATFKHPRTTGSHPKSENKIVPSSCDSLK
RNHL-TPKKVEMQRSLPGSLLPLENPKDTCASKSESKIDLT-VSSDAPDHFSGQQENL-N
SMKK--RNVNFSAAETKSDKKDCAAFAICDQKSVHG-TFSPDHETLLQKFLKNSPDPTQK
SCLSDINPETDVSLVPDA-SVLSKPIFCFVKDVHPDLEMN-DTVFELQDNDIVNSSIKNS
S---CMTSPEPICIQNKIPTLQINKLQPAETESEDKYMKDTLNPNTVHTFGASGHITLNV
NQGAEYSLSEQQ--NDENSKVLTQNAATYWNELPQSACNPTYNSSEHLFG-TSYPYSAWC
VYHYSS--SNGNAITQTYQGITSYEVQP---SPSGLLTTVAS-----TAQGTHSNLLYSQ
YFTYFAGEPQANGFVPVNGYFQSQIPA-SNFRQPIFSQYASHQPLPQATYPYLPNRFVPP
EVPWVYAPWH-QESFHPGH--

--------MATNKMEMKETAKQNTLWQMSST----NEPLLNTG-EVNPLKKFTIPKIRRT
AGKVYLSPCCTNSREYSFIHDTLNQRRLDVSCDLQS-LWQFGDTKLIHNEELEKNFTAKR
S

PF12509 // ENSGT00390000006260_0_Domain_0 (122, 279)

EMRESGRHCRELEEHFCFLALPQSDVAEIYQNGISTRA--STLKILGNPLLGIYMFRHV
DIALNYSHSRSITVESILIFKV-LFGKVK------KIQPSMDKNKVSLDPSPNFDCHMSR
NAPSLKDTIE-LQAYSSAVYFYEYSVLSKPVDKPRQCL

ENSGT00390000006260_0_Linker_0_1 (279, 2115)

PYAVVTVKFIGSKVDNGHLTTS
LRFLSTGFPKRAERTCSLNNCTVAKRIGKGKDATVIFEHFKKPVDPF---VQENCLYSAP
NSEINHSNSNISNSCGNVQNG-NISIPETYSGQTEHNLVEIRDTSQVPAHDSDISLTPSD
ANASV-NGDFVLNWTSLKNILSGLNAAFPLHNNTGSSTVTTSKFIKDPRLMRREESTGGQ
SNSAGLNEILQFEKSLDYVNSEIN-LSSTRSNSASSSEVVLGDHAVFTNCLDAPCFNISV
DDSQSWAHNIGSEDYDCIPPDKVTMAGQCKDQ---G-NFSFPISVSNVVSEVKNQNHSEE
KAQRAQQ---------------------------ESV---NAYTKEYNSHISQKLQSSNL
KTIYQTGYQMS-TIFPLQKKVS-IDEYLQNTRKMKNF-TDMEDNS--KHEEKQTSRKKIE
N-DFSNETKISPIDNYIVLHQE--YKESECHNYFGENCDKTLITQEL-EIPK-SSTSTIK
DKDELDHPALKWQ--VT-PSLESLSQKYPQHFVENED-NIHTNLAVAQKLMELKLGKIN-
QNCASIVTEAFQKPKDVPQAKEPLIDRVISSYNIETAHDDSNCNITREHVCIYRK--NEP
VSLENSQRDYKETAYVE---DKGQDHSLFCNSRLNNNIG---LNVNFK-EQRDNYKE---
---NEKEAKE-N-NPSSEENNLENIYGDEKPGSHTN--ENFGI-IDEKEE-NKNYNIEIL
SSEEFSTTFNLICREK-YVSPKTAFLES--EEDTISAMTQKDTE-NTGRSIEHLASTT-F
PEI---ASSSVCVASNAAVQIASATIPALI-TNNEDDQIYQFKETCSSESPDFGLLVKHR
VSGCEIDMDKNKLQESFHQSIN-EN---LVLQSIELESEIEIELEDCDDAFV--FQLDTH
SHENMLCEEFVTSYKALKSRITWEGLLALDNGEIEVLEGTTGRENSDQQYSKESNYFYSS
AQNNETELPSPILLPDLQIRIT-NIFRPGFSPTADCLALKDNFCTHIIDATKLEINKE--
----DEETLGFGIYSQPSGENTDYPCEDKVGNI-RQESGLVSKA-EISLSFDFS-NNTDV
---NHMSE-NQNSESLFTEPSNVT-AIDDGSGSFSTKSK-TVYNDTKNNKEVESRSNKRK
L-YTSSRDQNISHKDLRWHEICGRKRRRTSQDSSECFSSLSQGRIKTFSQSEKHIKSVLD
ILRGEASLCKSKRLSRKLDKAVIHLKKAHRRVHTSLQLIAKVGEK-GRGPLPKSYAIICN
DF-WESCDLQGYSSLSQRRYYSTKYFLSKRKYDKQKKKRALKADISKSLTHVSKYKSYK-
T------SRG--KKCLSRKRMASSVSNSHPI-IHMGEFSNQE-HPESQLPVSSTSQITSQ
S-VYYNSSVSNPSLSEEHQLFSGK-TRSLFSPNHSDEKLIEKENQIDTEFLSSISNYEKL
ENHSANH--K---DATKENCCKINEVINESNSISSSCIKENNIDYSTGN-DYDAICIDHT
KVKTDVLISVLDSNMEHFLNADLYQQNNLILSDCKRNLEVNFPIEKCTVPIERSKQNIIT
GNFLMDPLNLTLIASKK-YSIPQLLSAAAVTDSEGESSKSYLDKQRILTIDSFAAST---
---TVSNCEQSCRGK--ELLKTEQCSSGNCLHTNGNETNVT-ENYELDVTS-VTEESKS-
-YGENV-------V-KLSSSDSSLLLKDNVKGPSSETCTVKKDTEDRIMQKVKQAEKA-K
DSV----YK-SMTE-GSTVKTEYKNQKNQIS-EES-CLSEKMIKTNLIDSHLS-TENTTT
E-SVSLKNAVSNPL

PF15326 // ENSGT00390000006260_0_Domain_1 (2115, 2382)

NKRE-KKGEIKV-SNVSQS---------------------------
-DLTLHSELVCISK---PEILGVNHMPVLPAHSETCEVTTFL-KKPTSYVSEFKDKHSSA
NHMDIIAQMSQILQRADEAASLQILQEETKVCLNILPLFVEAFERKQECSVEQILISREL
LVDQNLWNNWKHTLKPCAVDTLVELQMMMETIQFIENKKRRLEGKPTFRSLLWYDETLYA
ELLGKPRGFQQQSNFYPGFQGRLKYDAFCELQTYHDQLVEL

ENSGT00390000006260_0_Linker_1_2 (2382, 2578)

LEETEREKNSYYAFLKYKR
QVNECEAIMKHCSDCFDFSLSVPFTCGVNFGDSLEDLEILRKSTLKLISVHG-DSPKVHS
YPGKQDHLWIIIEIISSKINFIKNNEVVCIKISLYGLEHIFFDAAKNLVWKERGQPFSKN
-SPKKDEEGLLTVNKYAFSKLQKIYDNLSKDLNSEP-ISSIGLEDTI-IAS--RNHP

PF15326 // ENSGT00390000006260_0_Domain_2 (2578, 2722)

INK
ATISIENCKFNS---TLLSHPDICCISEILDQAEFADLKKLQDLTLRCTDHLEILKKYFQ
ILQDDNIDNIFITEENVLDMVKNHSHAAIILKPESIEMYIEIVMVSETIHFLKNSIAKKL
DKQRFRGMLWFDLSLLPELVQCQEKMASFSFLKENSTDVCLWKVIETAISELKKDLDIIY
KYNE-AVNCSYALHLISRELQELSEIKKLLKKSEYPTSTYVEFVPCIASINYGSTITELE
YNYNQFSTLLKNIMSAPRKDLGKMAHIMKVMKTIEHMKIICAKNAELTISFILCQMLCNR
RKILQ-LKRREKLIVHVVKPEENINKSSISI-MIPPISECLIKNISKSSKQRPSSADKCE
D-SQEQQKN-TVSSCKKLKVDMKDVTKISREKATFKHPRTTGSHPQSKKKIVSSSSNNLK
KNHL-TPKMVEMQRSLPGSL--LENPKDTCTSKSESKIDLT-VS----EHFTGQQENL-T
SMKK--TSVNFSAAETKSGNKDCAAFAICDQKSVHD-TFSPDHERVMQKFLKNSPDPTQK
SHLSAINPGTDVSLVPDI-SVLSKPIICVEKNSRIDLEMN-DTVFKLQDNDIVNSSIKNS
T---CVTSPEPIFIQNKIPTLQINELQPAETESEDKYMKDTLNPNTVHTFGGPGHITLNV
NQTAEYSFSEQQ--NDENSKVLTQNAATYWNELPQSACTPVCNSSENLFG-TSYPYYSWY
VYHYSS--SNGNAITQTYQGITSYEVQP---PSSGLLTTVAN-----TTQSTHSNLLYSQ
YFTYFAMEPQANNFVPVNGYCQSQIPAAYNFQQPIFSQYASHQPLPQAAYPYLPNLDVPP
EVPWTYAPWH-QQSFHPGH--

--------MATNKMEMKETAKQNTLWQMSST----SEPMLNTR-EVNPLKKFTIPKIRRT
AEKVYLSPCYTNSREYSFIHDTLNQCRLDVSCDLQS-LWQFGDTKLVHNEELEKNFTTKR
S

PF12509 // ENSGT00390000006260_0_Domain_0 (122, 279)

EMRESGRHCRELEEHFCFLALPQSDVAQIYQNGISTRA--STLKILGNPLLGIYMFRHV
DIALNYSHSRSITVESILIFKV-LFGKVK------KIQPSVDKNKVSLDPSPNFDCHMSR
NAPSLKDTIE-LQAYSSAVYFYEYSVLSKPVDKPRQCL

ENSGT00390000006260_0_Linker_0_1 (279, 2115)

PYAVVTVKFLGSKVDNGYLMTS
LRFLSTGFPKRAERTCSLNNCTVAKRIGKGKDATVIFEHFKKPVDPF---IQENCLCNIL
NSEINPSNSHISDSYGNVQNG-NISIPETYNGQAEHNLAEIRDTSQVLAHDSDLPLMPSD
AKESV-NGDLLLNWTSLKNILSSLNAAFPLPNNTGSSTVTTSKFIKDPRLMRREESIGEQ
SNTAGLNEILQFEKSLDNVNSEIK---STPSNSASSSEVVPGDCAVLTNCLDAPCFKTCV
NDSQSWAHNTGSEDYDCVPPNKVTMAGQCKDQ---G-NFSFPISVSNVVSEVENQNHSEE
KVQRAQQ---------------------------ELG---NAYKKEYNSRISQESQSSDL
KTIYQTGHQMS-TIFPLKKKVS-IDEYLQNTGKMKNF-TDLKDNS--KHEEKQTSWKEID
N-DFTNETKISPMDNYIVLHQE--YKESESHNSFEKSCGKILITQEL-EIPK-SSTSAIK
DKDELDHLALEWQ--IT-PSLESLSQKHPQHSVEYED-NIHTSLAISQKLMELKLGKIN-
ANCASIITKAFPKPKDIPEAKEMLIDTVISSYNIETAHDNSNCSITRKHICVHRKNENEP
VSLEDIQRDYKETAYVE---DRGQDHSLFCNSQL-NDIC---LNVNFK-EQRDNYKE---
---SQNEAKE-N-NASSVENNIENIYGDKKQDSHTN--ENFSY-IDEKEE-KNYNNIEIL
SSEEFSATFNLICREK-YVSAATALLES--EEDTISAMKQKDTE-NTGRSVEHLASTA-F
PEI---ASSSVCVASNAAVQIASATMPVLS-ISNDEHQIYQFKETCSSESPDFGLLVKHR
VSDCEIDKDKNKSQESFHQSIN-EN---LVLQSIELESEIEIELEDCDDAFI--FQQDTH
SHENMLCEEFVTSYKALKSRISWEGILALDNGEMEVLESTAGRENSDQHYSKESNYFYSS
TQSSETELPSPILLPDLQIRIT-NIFRPGFSPTVDSLALKDNFCTHVTEATKPEINKE--
----DGEILGFDIYSQPSGENSDYPCEDKVDNI-RQESGPMSKS-EISLSFDLS-HNTDV
---NHRSK-NQNSESLSSEPSNVT-TVDNGSTCFFTKSK-TDYNDTKNKKEVESRISERK
L-HTSSRDQNI-HKDLRQHKIYGRKRRLTSQDSSECFSSLSQGRIKTFSQSEKHIKSVLN
ILSGEASLCKSKCLSKKLDKAVTHLKKAHRRVHTSLQLITKVGEK-RKGPLPKSYAIICN
NF-WESCDLQDYSSVSRRKYYSTKHFLSKRKYDKRRKKRAPKADISKSLTYVSKHKSYN-
T------SGE--KQCLSRKSMASGVSKSHPT-IHVGEFHNQE-HPESQLPISSTSQSTSQ
S-VYYNSSVSNPSLSEEHQPFSGK-TGCLFSPDHSDEKLIEKENQIDTKFLSSTSKHEKL
EKHSANHNVK---DTTKENSCEANQVINESNSISLSCIKE-NINYSTGN-DYDATCIGCT
KVKTDVLISVLDSNVKHFLN-DLYQQENLTLSDYKRNLEVKW-----TAPIERCKQSIIT
GNFLMDPLNLTLIASKK-YSIPQL-SASAVTDSEGESSKSYLDKQRILTIDSFAAST---
---TIPCREQSCRGK--ELLKTEQCSSGNCLHTDGNETNVT-ENYELDIAS-VTEESRS-
-YGENI-------V-KLSSSDSSLLLKDNVKGSSSETCIAKKDTEDRIMWKVKQVEKA-K
DSV----YKSSMTE-GSAVNTEYKNQNNQIS-EEC-CLNEKIIKTNLIDSHLS-TKNNTT
E-SVSLKNTVSNPL

PF15326 // ENSGT00390000006260_0_Domain_1 (2115, 2382)

NKRE-K-AEIKV-TNDSQS---------------------------
-DLTLHSEIAYISK---PGILGVNHTPILPAHSETCKVTTLL-KKPASYMSELKEKHCSA
NHTAFIANLSQILQRADEASSLQILQEETKICLNILPLFVEAFERKQECSVEQILISREL
LVDQNLWNNCKHTLKPSAVDTLVELQMMMETIQFIENKKRRLEGEPTFRSLLWYDETLYA
ELLGKPRGFQQQSNFYPGFQGRLKYNAFCELQTYHDQLVEL

ENSGT00390000006260_0_Linker_1_2 (2382, 2600)

LEETKREKNSYYVFLKYKR
QVNECEAIMEHCSDCFDFSLSVPFTCGVNFGDNLEDLEILRKSTLKLISACE-DSPKVHS
YPGKQDHLWIIIEMISSKVNFIKNNEAVCIKISLYGLEHIFFDAAKNLVWKEKTQSFSKK
YSQKEDKERLLRVNKCAFSKLQKIYDTLSKDLNNEP-ISPVGLEEDTIIASRKSDHPINK
ATIGIENSKFSS---SLLT

PF15326 // ENSGT00390000006260_0_Domain_2 (2600, 2722)

HPDIYCISEILDQAEFADLKKLQDLTLRCTDHLEILKKYFQ
MLQDDNMDNIFITEENVLDVVKNHSHEAILLKPEAIEMYIEIVMVSETIHFLKNSIAKKL
DKQRFRGMLWFDLSLLPELVQCQEKMTSFSFLKDNSTDVCLWKVIESAISELKKDLDIIY
KYDE-AVNRSYAIHLLSRELQELSEIKKLLKNSKYFISTYIDFVPYITSINYGSTMMELE
YNYNQFSTLLKNVMSAPRKDLGKMAHIMKVMKTIEHMKIICAKNAELTISFFLCQMLYNG
RKILQ-LKTKEKMNIHVVKPGGNNNKFGISM-MVPPISECINKNISNSSKKRPSTVDKCE
D-SQEQQKNTTISSCKKLKVDMKGVTKINRENATFKHPRTTGSHPQSENKIVSSSSNNLK
RNHL-TSKKVEMQRSLPGSLLPLENPKDTCTSKLESKIDLT-VSSDAPDHFTGKQENL-N
SMRK--RNMNFSAVETKSDEKDCAAFAICDQKSTHG-TFSPGHEILLQKCLKNSPDPSQN
SCLSDINPETDVSLVPDA-SVLSKPIFCLVKDIHTDLEMN-DTVFELQDNDTVNSSIKNS
S---CVTSPEPICIQNKIPALQINKLQPAETESEDKYMKNTLNPNTVHTFGASGHITLNV
NQGAEYSLSEQQ--NDKTSKVLMQNAATYWNELPQSACTPTYNSSEHLFG-TSYPYSAWC
VYHYSS--SNGNGITQTYQGITSYELQS---PPSGLLTTVASGQGAQCAQGAHSNLLYSQ
YFTYFAGEPQANGFVPVNGYFQSQIPA-YNFQQPVFSQYASHQPLPQTTYPYLPNRDVPP
EVPWVYAPWH-QESFHPQH--

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----FFIYVSTEKACSLSNCTVAKRIGKGKDATVIFEHFRKPVDLF---SQENCPCKAL
TSETDSSSLESSSSHRSVQNG-NSCVFDTYSRHTDN-LSEVGDASQVHTHNSALSLMPTA
NTASG-NGDL-FSVTYLRSILSSISAVLPSQSSTGSSTVITSKLIKDPRLMKREQSMRKQ
NNAAGLSDTLPFDKSVGHGNSEIK-LTCMPASLVSSPETTPADHAL-TNCSDISCFKFSS
ERSYCQTHNMGSREYDSTTVSKIAITEQCKEQ---S-GISFPRYLPNAISNVEKQKYNEE
E--EAQKRSNIPVLTEQSNEPQN---------SFRSE--KNTYSKDYQSHISTASWSSDL
NNVYKVGHKMS-AVFPIQNKGN-LDEYMQNTGMMRTF-ISPEDGS--KCV-NQTCWKETV
N-YFTDKTKSSPIDSCITLDQK--HKECGNLNSLTGNGDKIPVTHKL-QMPK-PPISTTE
DKNELDRAVVELECNLT-PDTGYLLQKHPQYSLEHKD-NIDTNFAMAQGLTELKVVQNN-
QNFINM-TDAFQEAKDIPLDREHFIDRVVSSSASDVSLDTSGGNMIGEYMCIQRENKND-
------EKDCKETSHTK---GNVQDHCLSYDAELSSDLN---LKINSQ-EQR---HE---
---NPNE--YKTD----------NINESEKQDFH-------AN-AVEMREIKSNTKVEIL
NSEECS-TFDSICGKK-GRPATSASSES---EDSMDSIKQRHAP-SDGRSVEHLVST--F
PEI---EVSSVCIASNATKQVVNTTILTLN-TNCEDHQKHQLKETCASEISDLGL-VKHG
IFNCEIDPDKDKLQD-FYQLVN-EN---SILQTYELGSEIEVELEDCNDASL--FPQNID
SQGNHLCEEFE-LYESLKSRIDWEGLFGNSNKEMEAISFARR-EGADPH-STDCNCVSFS
SQKDRRELHNPIFLPDLQVTIT-NLISLRISPTDDSLESKGNFYKCVTESTEPEANE---
-----GKPFGFSIYSQH----SGFSCENKCGDS-VQELEYVSKS-GTSHSSNSS-HRTCV
---SHISG-KPNSNSLSTESCNVT-VINEKSKC-PRKSK-HDFNDTRNKKDMESRNGKRN
LHAS-SRSQNISHKDLRQHETHEKRRKPASYDSSERFSSLSQGRIKTFSQSERHIRNVLD
ILNNEASLCKSKHLSRKLDKAVLHLKKAHRRVHTSLQLISKVGKK-RKGPLPKAYSVICN
NF-WESCDLQGDSWMSERR---SRHFLSKRRYDKQGEKR-LRFDVDESLAPVSKHRSYR-
T------NRERISEYLSRGIMSGHVSSSLTT-FHVREFCDG--LHQSQLPLAYTSQTISQ
L-GYTNSIVRN-ASSSELEHFSET-SGHTLY---PGETVTEKEYQTG-------IDSAKL
GNHSTHN-IK---DITKENNSEDETVVCESNSVSLSSMKEN-ISHSQDK--CDLTCKAN-
---TDIVVSVLDLNKKHFLNVGICEQDNLVS-DGTRNGGTILPVEKCTVLREIE--P---
----SIPTGN----------IPPL-SPILLTAGEEESSLG---ENR--------------
------------------------------LHLKENEVNIT-KHSKLDLMS-VNKESKS-
-CNKNI-------K--PSSNGGSLLLKENVKVP--SKTYMAKYIEEEKMKKIEQAV----
-------YQAVV--------TGYKHQNKILK-EGSFHSHKKIIKNDLTDSCLG-IKNSTL
E-TTALKNIPS-QLS

PF15326 // ENSGT00390000006260_0_Domain_1 (2116, 2382)

KRQ-KVGQMKQ-----QS---------------------------
-D--------CPSK---PATAGTNCRPDLHENSEVPAE-----KKPPTHMQGLKEGHRVA
NYTSRVTELSQILQKADTAVSLKVLEEETKVCQNLLPLFVEAFERKQECSLDQILISRKL
MVEQNLWDNCRFKLKPSAVDTWVELQMAMETIQFIENKKRFLEGKVTFRSLLWYDESLYS
ELLSRPRGYQLQSNFYPAFQRRLKYNAFCELQSYYHQLVEI

ENSGT00390000006260_0_Linker_1_2 (2382, 2603)

LAETKKENNSYYAFLKYKR
QIKECEAIKRHYSDCFDFCLSVPFTCGVNFGDSLADLEALRKSVLKLISMHA-GSPKAHC
YPGKEDHLWIILEVVSSKVSFIKSNEEISIKICLYGLEHIYFDAAKSLVWKEKSQSFPKR
HSE--NRE-METINECAFSKWEKIYDVLSKDLDNES-TPSIGLKEDDMIVSRQSA-LV--
---SLPNCKLNK---AWLSYPD

PF15326 // ENSGT00390000006260_0_Domain_2 (2603, 2724)

ICCISEILDQAKSADLETLQDLTLKCTVHLETLKKYFQ
MLQEDNINNIFITEENVLDIL-NHNHGAVILKPEAIEIYIETIMLSETVHFLKNSIAEKL
HNQRFRGMLWFDWSLLPELVGCQKEMASFSV-DDNQTD-CLWKVIETAISHLKKELCILY
DYGE-AVNCSYALRLFSRELKELLGIKRLLKMSKYSVSTYIDLAPHIACVNYGNTVEELD
HNYNQLFTLLKNIMSVPQKDFGKMVHIMKVLKTIKHMKMIRAKGTKLSTHLLFFQMLRNR
RNTLQ-FSKKEKREMPTTEPEENSSQPDISV-QTPLAAGCTIKNIASSSKKRPVTADKCE
V-SQGKENTDAVSNCKRQKVTMKDVR--NRQKTISKNPRTTESHPIDENKIGSNLPDSLK
RDSA-SPEMVKRPSSTPGLLSPSENIEDTCTPKPESKIELTDSSSGVSEYLAEQQESL-N
GIMK--GNVNFNAAQTN--KKDH-PLVSCDQKDIAA-TCSPDNTP-AQKLHGNPVDH-TQ
ICPSNVRPGNDDSLMPRA-SV---PASHSVRAIHSNLEMN-DTDFEHEDNKILDLSVKDC
T---CTSSPEPVCIQDKIPVLQVNKTQPI---------KDAPNPSIS-PFGSYGSLALDV
NQRAQCTVSEQG---GKNPKVVTQKVGTSWNAPPQSTYTTVYNSSEHSFG-GSYPYYAWC
FYQCSS--SSGTAVTRTYQGMTTYET------PPPMMTAVAS-----AVQNTHFNHSYSE
HFSYFARQQQANAFIPGNGYSPSPMPVSYSYQQPVYSQFSSHQLVPQAAYPYPPNPGVLP
QVPWTYAPWQ-QSSFPPRH--

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--MTYFFIYVSTERACSLNNCTIAKRIGKGKDATVIFEHFRKPVDPF---VQENCPCKAL
NSEMGPFSSDTSSSYGNVQNG-NNSVLEAYNRQTEN-SSNLRDASQVYTHNSGFSFIPTG
NTASG-NGDL-FSVTYLRSILSSISAAFPSHNNTGSSTVITSKLIKDPRLMKREQSMRNK
SDTAGLSDVLPLDKSLGCGDSQIK-LTCMPTSSISSSE-VPADNTI-TSCLNASCFKFSS
ESSHYQAHNSSSKGHDCIASSSIAVTEQFKEQ---H-SSSFPSSLSNAFSDVRKQKHSEE
QVQRAQMRSNVPVLTALSSESRN---------SDE---SENTCSNDSQGHFSQESPSSDI
NSIYKVGHQMS-TVFPAQKKGN-LCEYIQDTGMMRAS-ISTEDST--KDGVNHTWCKETV
---LSNETVSSPIDNSNTLYQE--HKEGGNLNSLSGNCEKIGVTHKL-QVPK-FPISSTG
DKNELYRAALELECSLT-PTIECLSQKYPQHSLEHED-N--TNFAMTQGLIELKTVQNN-
QNFGNILSDAFQEAKDVPLASEKLIDRVISSAAIDISLDSSVCNIIGEYTCVRRENENGE
ASPYNCHKE--EASRVK---DGVQDHSLSYDAELSCDLN---LKINLQ-EQRD--DK---
---NPNEAKE---------HNTDNINGSEKQDCLAN--DHFTN-IVEMREIKSNTEVEIL
NSEECF-TFNSFRGKN-GKPAETASSES---E----AVEQRHAP-NDQRGLEHLVSS--F
PEI---EGSSVCVASNATKQIVGTTVLTVS-TSLGDHQKDELKEICSSESSDLGL-VKHS
ISECEIDTDKDKLQD-FHQLVN-EN---SALK-TGLGSEIEVDLEH-DNASV--FQQNMH
SQGNDLCEEFE-LYESLKSRIDWEGLFGSSYEEIESSSFARR-EGTDQHSSTECNCVSFC
SQ-DKRELHNPIFLPDLQVTIT-NLLSLRISPTDESLELKDNFYKQVTESTEPETNKE--
-----GNASGFGMCSQPSGENSSFSCANKFGNS-VQESGDVSKS-ESSHSSNSS-HNTHV
---DQGSG-KPNNDSLSTEPSNVT-VMNDKSKC-PTKSK-PVFNDTRNKKDMQSRSSKRT
LHASSSRGQNIANKDLREHETHEKKRRPTSHGSSDRFSSLSQGRIKTFSQSEKHIRNVLN
ILNNEASLCKSKHLSRKLNKAVLHLKKAHRRVHTSLQLISKVGQK-RKGPLPKAYAVIHN
NF-WESCDHQGDSLMSERRY--SKHFLSKRKYDKQGDKRFLRFDIEESLTPVSKHRLYR-
T------NRERIAECLSNEVMSGHVSSSLTT-FHVREFCDEEQFPEPQLPLAYTSQSISQ
L-EYTNSIVGN-ESSSELEHFSET-SGNMLD---PKETLTEKEYQTHTQLC--NSDSAKL
KNHTTHS-IR---DIAKECNSEDKTVLCESNPVYLSFIKEN-TSHSPDK-SYDSNCKAN-
---TDIHISVLGSKKKHILSVDIYEQDNCVS-DGVKSGEAIFPIEKCTVPMETT--S---
----SIPTEN--IASKS-YTIPPV-SSILVTAGEEESSVG---ENGL-------------
------------------------------FDVNENEMNIT-MHSKLDLTS-VTEESKI-
-CKKNM-------K-NLSCNDSSMLLKENITGP--SKRYMAKYIEEEKIRKIEQAV----
-------YKKIITE-GSPISFKYKSQNKILK-EKSFHVNKKIITNNLTDSHLS-IKNSTV
D-TIALKDIPN-Q

PF15326 // ENSGT00390000006260_0_Domain_1 (2114, 2381)

LKERK-EAGQIKV-NNNSHS---------------------------
-D--------CLSK---PAIVETNHRPVLHGNPKVATL-----QKE-------LKEHRSP
NYTSHVTELSQILQRADEAASLQILEEETKLCQNILPLFVQAFERQQECSIDQILISRKL
LVEQNLWNNCRLKLKPCAVDTWVELQMAMETIQFIENKKRFLEGKPTFRSLLWYDESLYS
ELLRRPRGYQLQSNFYPGFQGRLKYNAFCELQNYHNQLVE

ENSGT00390000006260_0_Linker_1_2 (2381, 2603)

FLTETKKENNSYYALLKYKR
QINECEAIMKHYSDCFDFCLSVPFACGVNFGDSLGDLETLRKSTLKLISVPG-GSPKVHS
YPGKKDHLWIIIEIVSSKVSFIKSNEEISIKICLYGLEHIYFDAAKSLVWKEKSCSLPKK
HSEK-NRE-MEEINERAFSKLKKIYDVLSKGLNNEP--TSIGLQEDAIIASKQST-LG--
---SISNCRLNK---AWLSYPD

PF15326 // ENSGT00390000006260_0_Domain_2 (2603, 2722)

ISCVGEILDQAKSADLEELQGLTLRCTDHLEILKKYFQ
MLQEDNIDNIFIMEENVLDMLSNHNLGAVILKPEAIEIYIEIVMISETIHYLKNLIAKKL
HNQRFRGMLWFDWSLLPELIGCQEEVVSLSV-GDTQTH-CLWKLVETAISVLKKELAVIY
EYGE-ASNCSYALHLFYRELKELTGVKRLLNNSKYSVSTYIDLVPHTASVNFGNTVAELE
HNYKQFFLLLKNVMSVPQKDFGKMVHIIKVMKTIEHMKLLSAKDTKLSTHLLFLQMLRNK
RNALQ-QNRQEKMETPVTEPGEDSSQPGVSE-QTPPGTECTVKNISDSSKKRPVTADTCE
V-SQGKGNTDTVPSWKKQKVTMKDVG--NIQ-TVSKHPSTTGSPPNDENKIGSNSSDSLK
SISA-SPEVVKRQSSVLGSVSPAESVQDTCTPKSESKVEPTDSLPDSLASLTEQQENS-N
VIEK--RNGNSSVAETN-DKKDC-PLVTCDQKDIDA-SYSPDHTP-AQESHKTPVDH-TQ
ISPSNLTAGNDDPLVPDA-SLLSVSASQSEKDVY----LS-GTDFHHENNKILNLSTEDC
T---GTSSPEPVCIKDKISVLQVDKTQPIKSESPKKSMTDAPNPNTA-PFGSYGNSALNV
NGTVQHTHSEQ------NSKVLTQKVGTSRNIPPQSACSPVHNSSAHSFG-TSYPYYSWC
FYQYSS--SNGTAVTHTYQGMTAYEIQQP--P-PPVLTTVAS-----TVQSTHFNRSYSE
HFSYFPGQPQANSFNPGNGYFPSHTPVSYNYQQPVYSQFASHQPVPQATYPYPPNPGAPP
QVPWTYAPWQ-QNPFLRRP--

--------MATNKMEMKETAKQNTLWQMSST----SEPMLNTR-EVNPLKKFTIPKIRRT
AEKVYLSPCYTNSREYSFIHDTLNQCRLDVSCDLQS-LWQFGDTKLVHNEELEKNFTTKR
S

PF12509 // ENSGT00390000006260_0_Domain_0 (122, 279)

EMRESGRHCRELEEHFCFLALPQSDVAQIYQNGISTRA--STLKILGNPLLGIYMFRHV
DIALNYSHSRSITVESILIFKV-LFGKVK------KIQPSVDKNKVSLDPSPNFDCHMSR
NAPSLKDTIE-LQAYSSAVYFYEYSVLSKPVDKPRQCL

ENSGT00390000006260_0_Linker_0_1 (279, 2115)

PYAVVTVKFLGSKVDNGYLMTS
LRFLSTGFPKRAERTCSLNNCTVAKRIGKGKDATVIFEHFKKPVDPF---VQENCLCNVL
NSEINPSNSHISNSYGNVQNG-NISIPETYNGQAEHNLAEIRDTSQVLAHDSDLSLMPSD
AKESV-NGDLLLNWTSLKNILSSLNAAFPLPNNTGSSTVTTSKFIKDPRLMRREESMGEQ
SNTAGLNEILQFEKSLDNVNSEIK---STPSNSASSSEVVPGDCAVLTNCLDAPCFKTCV
NDSQSWAHNTGSEDYDCVPPNKVTMARQCKDQ---G-NFSFPISVSNVVSEVENQNHSEE
RVQRAQQ---------------------------ESG---NAYKKEYNSRISQESQSSDL
KTIYQTGHQMS-TIFPLKKKVS-IDEYLQNTGKMKNF-TDLKDNS--KHEEKQTSWKEID
N-DFTNETKISPMDNYIVLHQE--YKESESHNSFEKSCDKILITQEL-EIPK-SSTSTIK
DKDELDHLALEWQ--IT-PSLESLSQKHPQHSVEYED-NIHTSLAISQKLMELKLGKIN-
ANCASIITEAFPKPKDIPEAKEMLIDTVISSYNIETAHDNSNCSITRKHVCVHRKNENEP
VSLEDIQRDYKETAYVE---DRGQDHSLFCNSQL-NDIC---LNVNFK-EQRDNYKE---
---SQNEAKE-N-NASSVENNIENIYGDKKQDSHTN--ENFSY-IDEKED-KNYNNIEIL
SSEEFSATFNLICREK-YESAATALLES--EEDTISAMKQKDTE-NTGRSVEHLASTA-F
PEI---ASSSVCVASNAAVQIASATMPVLS-ISNDEHQINQFKETCSSEIPDFGLLVKHR
VSDCEIDKDENKSQESFHQSIN-EN---LVLQSIELESEIEIELEDCDDAFI--FQQDTH
SHENMLCEEFVTSYKALKSRISWEGILALDNGEMEVLESTAGRENSDQHYSKESNYFYSS
TQSSETELPSPILLPDLQIRIT-NIFRPGFSPIVDSLALKDNFCTHVTEATKPEINKE--
----DGEILGFDIYSQPSGENSDYPCEDKVDNI-RQESGPMSKS-EISLSFDLS-HNTDV
---NHRSK-NQNSESLSSEPSNVT-TVDNGSRCFFTKSK-TDYNDTKNKKEVESKISKRK
L-HTSSRDQNI-HEDLRQHKIYGRKRRQTSQDSSECFSSLSQGRIKTFSQSEKHIKSVLN
ILSGEASLCKSKCLSKKLDKAVTHLKKAHRRVHTSLQLITKVGEK-RKGPLPKSYAIICN
NF-WESCDLQDYSSVSQRKYYSTKHFLSKRKYDKRRKKRAPKAGISKSLTYVSKHKSYN-
T------SGE--KQCLSRKSMASGVSKSHPT-IHVGEFHNQE-HPESQLPISSTSQSTSQ
S-VYYNSSLSNPSLSEEHQPFSGK-TGCRFSPDHSDEKLIEKENQIDTKFLSSTSKYEKL
EKHSANHNVK---DTTTENSCEANQVINESNSISLSCIKE-NINYSTGN-DYDATCIGCT
KVKTDVLISVLDSNVKHFLN-DLYQQENLTLSDYKRNLEVKW-----TAPIERCEQSIIT
GNFLMDPLNLTLIASKK-YSIPQL-SASAVTDSEGESSKSYLDKQRILTIDSFAAST---
---TIPCCEQSCRGK--ELLKTEQCSSGNCLHTDGNETNVT-ENYELDIAS-VTEESRS-
-YGENI-------V-KLSSSDSSLLLKDNVKGSSSETCIVKKDTEDTIMWKVKQVEKA-K
DSV----YKSSMTE-GSAVNTEYKNQNNQIS-EES-CLNEKIIKTNLIDSHLS-TKNNTT
E-SVSLKNTVSNPL

PF15326 // ENSGT00390000006260_0_Domain_1 (2115, 2382)

NKRE-K-AEIKV-TNDLQS---------------------------
-DLTLHSEIACISK---PGILGVNHTPILPAHSETCKVTTLL-KKPASYMSELKEKHCSA
NHTAFIANLSQILQRADEASSLQILQEETKVCLNILPLFVEAFERKQECSVEQILISREL
LVDQNLWNNCKHTLKPSAVDTLVELQMMMETIQFIENKKKRLEGEPTFRSLLWYDETLYA
ELLGKPRGFQQQSNFYPGFQGRLKYNAFCELQTYHDQLVEL

ENSGT00390000006260_0_Linker_1_2 (2382, 2601)

LEETKREKNSYYVFLKYKR
QVNECEAIMEHCSDCFDFSLSVPFTCGVNFGDSLEDLEILRKSTLKLISACE-DSPKVHS
YPGKQDHLWIIIEMISSKVNFIKNSEAVRIKISLYGLEHIFFDAAKNLVWKEKTQSFSKK
YSQKEDKERLLRVNKCAFSKLQKIYDTLSKDLNNEP-ISPVGLEEDTIIASRKSDHPINK
ATIGIENSKFSS---SLLTY

PF15326 // ENSGT00390000006260_0_Domain_2 (2601, 2722)

PDIYCISEILDQAEFADLKKLQDLTLRCTDHLEILKKYFQ
MLQDDNMDNIFITEENVLDVVKNHSHEAILLKPEAIEMYIEIIMVSETIHFLKNSIAKKL
DKQRFRSMLWFDLSLLPELVQCQEKMTSFSFLKDNSTDVCLWKVIESAISELKKDLDIIY
KYDE-AVNRSYAIHLLSRELQELSEIKKLLKNSKYFISTYIDFVPYITSINYGSTMMELE
YNYNQFSTLLKNVMSAPRKDLGKMAHIMKVIKTIEHMKIICAKNAELTISFFLCQMLYNG
RKILQ-LKRKEKMNIHIVKPGENNNKFSISM-MVPPISECINKNISNSSKKRPSTVDKCE
D-SQEQQKNTTISSCKKLKVDMKGVTKINRENATFKHPRTTGSHPQSENKIVSSSSNNLK
RNHL-TSKKVEMQRSLPGSLLPLENPKDTCTSKSESKIDLT-VSSDAPDHFTGQQENL-N
SMRK--RNVNFSAVETKSDEKDCAAFAICDQKSAHG-TFSPDREILLQKFLKNSPDPSQN
SCLSDINPETDVSLVPDA-SVLSKPIFCLVKDIHTDLEMN-DTVFELQDNDIVNSSIKNS
S---CVTSPEPICIQNKIPALQINKLQPAETESEDKYMKNTSNPNTVHTFGASGHITLNV
NQGAEYSLSEQQ--NDKTSKVLTQNAATYWNELPQSACTPTYNSSEHLFG-TSYPYSAWC
VYHYSS--SNGNGITQAYQGITSYELQS---PPSGLLTTVASGQGAQCAQGAHSNLLYSQ
YFTYFAGEPQANGFVPVNGYFQSQIPT-YNFQQPVFSQYASHQPLPQTTYPYLPNRDVPP
EVPWVYAPWH-QESFHPQH--

------------------------------------------ERERELGENFNIPKIT--
LDKVILTECFANKREYDEVKQCLIQGCLAKDNNF--ERWPIEKIEML

PF12509 // ENSGT00390000006260_0_Domain_0 (108, 279)

QNKHLEEEFVMKR
SRLRQERKPDKEL---PCFLVVAKDDVSKICQSGLHIGQNLKIMDELGNRHLGVYLFRHV
DIALKYAAIHSSHIENVIIFRVS-ESKIPMGLKRAVMKPL--LKKPSLDPTHLHNFWRVS
NLPFLDKVLERLEILNAKVYVYEYNELAKPVDRPRQCLPYAVVKIKCVNLKMHAGFTLTP
SKSRPKGLPKRVERDLPLENCTRVTRIGKN---QLIYEHFRKPYTED----LENCSPAE-
----------SCPFSGRIQNW-NGSSSETQHRKAKHNFSTRWDIAVNEL-----T----I
QKTSGMDACIDIRSDHIEN-EKSLEMPIRVPPESGFSIVTTSKSIKDPRLVKRQQN----
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----------SIERACSLNNCTIAKRIGKGKDATVIFEHFRKPVDPF---NQENCPCKVP
NSERSPSNMDTSCSYGN------NFVLREYSRQTDN-SSEVRDASQVHTYNSGLSFMSTA
NTASG-DGDL-FSVTYLRSILNSISAALPCQSSTSSSTVITSKLIKDPRLMKREQSMRKQ
SNSADLSDGLPLDKSVGHGNSEVK-LTCMPTSSISSPESIPADDAV-ANCSDASCFRISS
ESSHCQTHTMGSKDSDCTASSKVAITEQCKEQ---S-TFSFPRYLPNAFSDVGKQSYNEE
EAQRAQKRSSFQVLTEQSNGTQN---------FFESE--KNTCCKDSQSHISKASWPSDL
SVVFKFGHQMS-TVFPIQEKGN-IDEYVQNTGMMRTF-ISPEDSS--RHVISQTWLKETV
N-SFTNETKSIPIANCIALHQE--YKEGENINSLTENCEKIADTPKL-QMPK-SPISTTK
DKNEVDHAALELEYNLT-PNTGCLSQKHPQYSLEPKD-NIHTNFAIAQGLIELKAIQNN-
QNLINIKTDAFQEANDVSLAREQLVDKVISSDAIDISLDSSGCNLIGEYMSIQRENENET
VSLYNIQKDCKESSHIK---DNVQDHTLPYDAELSSDLN---LKIILQ-EQRN--DE---
---NPNEAKEKDD----------CYAN-----------------IVE----MSNTKVEIL
NSEECT-TFNSIWGKK-DRPAKAASSES---EDSMTAINQKYIP-NDGRSVER-LST--F
PET---KESSVCVASDATKKVVSTTVLTES-TNHGDHQKHHLKE---PEISGLGF-VKQG
ISDCEI--DTDKLQD-LCHLVN-EN---SVHQTFALGSEIEVELEEHNDAPL--FQQNIG
NNGNDLCEEFE----TLKSRIDWEGLFGKSYEEMEASSFTRR-EN-----TAECNCVSFS
SQKDKREHQNSVFLPDLQVTIT-NLISLKISPTDDSLESKDNFYKPVTKSTEPEANEK--
-----RKAFGFGIYSQPFEENLGFSCENKLGNS-VQESGHVSKS-GISHSSSSSLNNTHV
---NHTPG-KPTSDSLSTEPSNVT-VISDKSKC-STKSK-PDFNDTRNKKDMESRSSKRN
QHAT-SRGQNISHKDLREHETHEKRRKSTNHYSSERFSSLSQGRIKTFSQSERRIRNVLN
ILNNEASLCKSKHLSRKLNKAVLHLKKAHRRVHTSLQLISKVGKK-RKGPLPKAYAIICN
NF-WESCDLQGDSLMSERRN-SDRHFLSKRRYDKQGEKR-LRFDIDESLASVSKHRTHR-
T------NRERIAECLSSETMSGHVSSSLTT-FHVREFCEEEQLHESQSPIPYTSQSISQ
L-EYTNSIVRT-TSSSESENFSET-SEYTLY---PDETLTEKEYQTGTQLS--KN-----
ESHTTCN-TK---NITKENNSEDKTVVCESNSVSLSFLKDN-ISHSQDK-SYDTTFKAN-
---TNKLVSVLDSNKP-FLNVDICE---QVS-DGTRNGETIFPVEKCTVLMEIT--P---
----NIPTGK--TANRR-NTIPPL-SPIIVTADEEESSVG---GNGL-------------
------------------------------FHVKENEVNIT-KHSKLDVTS-VTEENQS-
-CKKNV-------K-KLSFNDSSLLLKENVKGP--SKAYMAKYNEEEKMRKIEQAV----
-------YPKMVTE-GSA-VTGYKHENKILK-EDSFHLHKKIIKNNLTDSRVG-VKNSTL
E-TTDLKNIFS-QLSKRQ-KAGQIKQLSNGSHS---------------------------
-N--------CPKS--

PF15326 // ENSGT00390000006260_0_Domain_1 (2177, 2380)

-A-TAGTSDRLVVHENSEVTVS-----QMKP-----LSHMEELQ
ESTSHITELSQILQRADEAVSLQVLEEETKVCQNILPLFVEAFERKQECSLEQILISRKL
LVEQNLWSNCKLQLKLCAIDTWVELQMAMETIQFIENKKRFLEGEPTFRSLLWYDESLYS
ELLLRPRGYQLQSNFYPAFQRRLKYNAFCELQRYYYQLI

ENSGT00390000006260_0_Linker_1_2 (2380, 2603)

E----TKKEKTSYYTFLKYKR
QMKECEAIMKHHSDCSEFCLSVPFSCGVNFGESLGDLEALRKSVLKLISTLR-GSPKVNS
YPGKEDHLWIILEMVSSKISFIKSNEEISIKICLYGLEHIYFDAAKSLVWKEKSHSFPRR
HSEV-NRE-LEEINECAFSEWKKIYDDLSNDLNNES-AQTIGLEESDMIASRQSA-LV--
---SVPNCKLNT---TWLSYPD

PF15326 // ENSGT00390000006260_0_Domain_2 (2603, 2721)

ICCISEILDQAKSADLEKLQDLTLRCTVHLEILKKYFQ
MLQEDNIDNIFITEENVLDML-NHNHGAVILKPEAIEIYIETVMLSETIHFLKNSIAKKL
HNQRFRGMLWFDWSLLPELVDCQEEMASFSL-DNNQPD-CLWKVIENAISHLKEELGVVC
DYSE-AVNCSYALCLFSRELKELSGIKRLLNTSEYSVSTYIDVVPHTASVNYGNTVIELE
HNYNQLFILLKNIMSVPQKDFGKMVHIIKVLKTIEHMKMINAKDTKLSTRLLFFQMLRNR
RNTLQ-LNKKERVATPIREPEENSSEPGVSV-QTPAAAEYTVRNISSSSKKRPVTADRHE
I-SQGKGNTGAVSNHKKQKVTMKDIS---RPKTVSENPRTTESHPND---------DSLK
RDSA-SPETVKRQSSTPGLLSPSENVQDSCTPKSESKVELTDSSSDVSEYLTEQHENL-N
GITK--RNVNFSAAETN-DKEDR-LLVTCDQNDIDA-TFSPDSTP-AQKLHENPTDH-TQ
ICPSDIGAGNDSPLVPNE-SL---PTSHPMRAIHSHLEMS-DTVFEHEDSEILDLSIKDC
T---CTSSPEPVCIQEKIPVLQVYETQPIKTESPEKCIKDAPNPRTT-PFGSYENSAIGV
SQTAQHT--EKD---GKSPEVLTQKVGTSWSAPPQSTCTAVYNSPEYAFG-TSYPYYAWR
FYQYSS--SNGTAVTHTYQEMTTYETA-----PPSMMTAVAS-----AVQNTHLNHSYSE
HFGYFAMQPQANACVPGNGYSPSPMPVSYNYQQPVYSQFTSHQLVPQAAHPYPPNPGVLP
QVPWTYAPWQ-QDPFPPRH--

---------MANKMEMEETAKQDTLWQMSST----SKPLLNTH-EVNPLKKFTIPKIRRT
AEKVYLSPCYTNSREYSFIHDTLNQCRLDVSCDLQS-LWQFGDTKLVHNEELEKNFTAKR
S

PF12509 // ENSGT00390000006260_0_Domain_0 (122, 279)

EMRESGRHCRELEEQFCFLALPQSDVAQIYQNGISTRA--STLKILGNPLLGIYMFRHV
DIALNYSHSQSITVESILIFKV-LFGKVK------KIQPSVDKNKVSLDPSPNFDCHMSR
NAPSLKDTIE-LQAYSSAVYFYEYSVLSKPVDKPRQCL

ENSGT00390000006260_0_Linker_0_1 (279, 2116)

PYAIVTVKFLGSKVDNGRLMTS
LRFLSTGFPKGAERTCSLNNCTVAKRIGKGKDATVTFVRFKKPVDPF---VQENCLCNAL
NSEINPFISNISNSYGNVQNG-NISIPETYSGQTEHNLAEIRDTSQVLAHDSDISLMPTD
AKESV-NGDLLLNWTSLKNILSGLNAAFPLHNKTGSSRVTTSKSIKDPRLMRREESMGEQ
SSTAGLNEILQFEKSSDNVNSEIK---STPSNSASSSEVVPGDHAVLTNGLDTPCFKTSV
NDSQSGAHNMGSEGYDCIPPNKVTMAGQCKDQ---G-NFSFPISVSNVVSEVENQNHSEE
KAQRAQQ---------------------------ESS---NAYTKEYSSHIFQDSQSSDL
KTIYQTGCQTS-TVFPLKKKVS-IDEYLQNTGKMKNF-ADLEDSS--KHEEKQTSWKEID
N-DFTNETKISPIDNYIVLHQE--YKESESHNSFGKSCDKILITQEL-EITK-SSTSTIK
DKDELDHLALEWQ--IT-PSFESLSQKHPQHSVEYEG-NIHTSLAIAQKLMELKLGKIN-
QNYASIITEAFPKPKDIPQAKEMFTDTVISSYNIETAHDSSNCSITREHICVHRKNENEP
VTLENIQRDYKETAYVE---NRGQDHNLFCNSQLSNDIC---LNVNFK-KQTD--KE---
---NQNEAKE-N-SASCVENNIENIYGDKKQDSHTN--ENFSN-IDEKED-KNYHNIEIL
SSEEFSTTFNLICREK-YVSAATALLES--EEDTISAVKQKDTE-NTGRSVEHLASTT-F
PKT---ASSSVCVASNAAIQIASAAMPALS-LNNDDHQIYQFKETCSSESPDFGLLVKHR
VSDCEIDTDKNKSQESFHQSIN-EN---LVLQSIELESEIEIELEDCDDAFI--FQQDTH
SHENMLCEEFVTSYKALKSRISWEGLLALDNREMEVLESTTGRENSDQHYSKESNYFYSS
TQNNETELTSPILLPDLQIKIT-NIFRPGFSPTADSLALKDNFCTHVTEATKPEINKE--
----DGEILGFDIYSQPFGENADYPCEDKVDNI-RQQSGPVSNS-EISLSFDLS-RNTDV
---NHTSE-NQNSESLFTETSNVT-TIDDGSRCFFTKSK-TDYNDTKNKKEVESRISKRK
L-HTSSRDQNIPHKDLRRHKIYGRKRRLTSQDSSECFSSLSQGRIKTFSQSEKHIKSVLN
ILSDEASLCKSKCLSRKLDKAVVHLKKAHRRVHTSLQLITKVGEE-RKGPLPKSYAIICN
NF-WESCDLQGYSSVSQRKYYSTKHFLSKRKYDKRRKKRAPKADISKSLTHVSKHKSYK-
T------SGE--KKCLSRKSMASSVSKSHPT-SHMGEFCNQE-HPESQLPVSSTSQSTSQ
S-VYYNSSVSNPSLSEEHQPFSGK-TGCLFSPDHSDEKLIEKENQIDTEFLSSTSKYEKL
EKHSANHNVK---DATKENSCEANEVINESNSVSLSCIKE-NINYSTGN-DYHATCVGHT
KAKTDVLISVLDSNVKHFLN-DLYQQGNLILSDCKRNLEVKW-----TDPIERPKQSIIT
GNFLMGPLNLTLIASEK-YSIPQL-SAAAVTDSEGESSKSYLDKQRILTVDSFAESS---
---AVPHCEQSCREK--ELLKTEQCSSGNCLHTDGNETNVT-ENYELDVAS-GTEENKS-
-YGENI-------V-ELSSSDSSLLLKDNVKGSSSETCIVRKDTEDRITWKVKQAEKA-K
DSV----YKRSMTE-GSTVNTEYKNQKNQIS-EES-CLNEKIITANLIDSHLS-TKNTTT
E-SVPLKNTVSNPLD

PF15326 // ENSGT00390000006260_0_Domain_1 (2116, 2382)

KRE-KKGEIKV-SNDSQS---------------------------
-DLTLRSEIAYISK---PGILGVSHTPILPAHSETCKVPTLL-KKPASYMSEFKEKHCSA
NHTALIANLSQILQRADEASSLQILQEETKVCLNILPLFVEAFERKQECSVEQILISREL
LVDQNLWNNCKHTLKPCAVDTLVELQMMMETIQFIENKKRRLEGEPTFRSLLWYDETLYA
ELLGKPRGFQQQSNFYPGFQGRLKYNAFCELQTYHDQLVEL

ENSGT00390000006260_0_Linker_1_2 (2382, 2585)

LEETKREKNSYYVFLKYKR
QVNECEAIMEHCSDCFDFSLSVPFTCGVNFGDSLEDLEILRKSTLKLINVCG-DSPKVHS
YPGKQDHLWIIIEMISSKVNFIKNNEAVRVKISLYGLEHIFFDAAKNLVWKERTQSFSKK
YSQKKDEERLLRVNKCAFSKLQKIYDTLSKDLNNEP-ISPIGLEEDTIIASRKSDNPINE
ATIS

PF15326 // ENSGT00390000006260_0_Domain_2 (2585, 2722)

IENSKFNS---NLLAHPDICCISEILDQAEFADLKKLQDLTLRCTDHLEILKKYFQ
MLQDNNMDNIFITEENVLDMVINHSHEAIILKPEAIEMYIEIVMVSETIHFLKNSIAKKL
DKQRFRGMLWFDLSLLPELVQCQEKMASFSFLKDNSTDVCLWKAIETAISELKKDLDIIC
KYNE-AVNCSYAIHLLSRELQELSEIKKLLKKSKYFISTYIDFVPYIASINYGSTLTELE
YNYNQFSTLLKNVMSAPRKDLGKMAHIRKVMKTIEHMKIICTKNAELTISFFLCQMLYNR
RKILQ-LKRKEKMNIHTVKPGENNNKFSIST-MLPAVSECINKNISNSSKKRPSTVDKCE
D-SQEQQQDDTISSCKKLKVDMKDVTKINREKATFKHPRTTGSHPQSENKIVPSSCDSLK
RNHL-TPKKVEMQRSLPGSLLPLENPKDTCASKSESKIDLT-VSSDAPDHFSGQQENL-N
SMKK--RNVNFSAAETKSDKKDCAAFAICDQKSVHG-TFSPDHETLLQKFLKNSPDPTQK
SCLSDINPETDVSLVPDA-SVLSKPIFCFVKDVHPDLEMN-DTVFELQDNDIVNSSIKNS
L---CMTSPEPICIQNKIPTLQINKLQPAETESEDKYMKDTLNPNTVHTFGASGHITLNV
NQGAEYSLSEQQ--NDENSKVLTQNAATYWNELPQSACNPTYNSSEHLFG-TSYPYSAWC
VYHYSS--SNGNAITQTYQGITSYEVQP---SPSGLLTTVAS-----TAQGTHSNLLYSQ
YFTYFAGEPQANGFVPVNGYFQSQIPA-SNFQQPIFSQYASHQPLPQATYPYLPNRFVPP
EVPWVYAPWH-QESFHPGHRK

--------MATNKMEMKETAKQNTLWQMIST----SEPLLNTG-EVNPLKKFTIPKIRRT
AGKVYLSACCTNSREYSFIHDTLNQGRLDVSCDLQS-LWQFGDTKLIHNEELEKNFTAKR
S

PF12509 // ENSGT00390000006260_0_Domain_0 (122, 279)

EMRESGRHCRELEEHFCFLALPQSDVAEIYQNGISTRA--STLKILGSPLLGIYMFRHV
DIALNYSHSRNITVESILIFKV-LFGKVK------KIQPSMDKNKVSLDPSPNFDCHMSR
NAPSLKDTIE-VQAYSSAVYFYEYSFLSKPVDKPRQCL

ENSGT00390000006260_0_Linker_0_1 (279, 2115)

PYAVVTVKFIGSKVDNGYLTTS
SRFLSTGFPKRAERTCSLNNCTVAKRIGKGKDATVIFEHFKKPVDPF---VQENCLYSAP
NSEINHSNSSISNSCGNVQNG-NISISETYSGQTEQNLVEIRDTSQVLAHDSDISVTPSD
ANASV-NGDFVLNWTSLKNILSSLNAAFPLHNNTGSSTVTTSKFIKDPRLMRREESTGGQ
SNSAGLNEILQFEKSLDYVNSEIN-LSSTQSNSASSSEVVTGDRAVFTNCLDAPCFNISV
DDSQSWARNIGSEDYDCIPPDKVTMAGQCKDR---G-NFSFPISVSNVVSEVKNQNYSEE
KVQSAQQ---------------------------ESV---NAYTKEYNSHISQESQSSNL
KTIYQTGYQMP-TILPLQKKVS-IDEYLQNTGKMKNF-TDLEDNS--KHEEKQTSRKKIE
N-DFTNETKINPIDNYIVLHQE--YKESESHNYFGKSCDKTLITQEL-EIPK-SSTSTIK
DKDELYHPALKWQ--VT-PSLESLSQKYPQHFVENEN-NIDTNLAIAQKLMELKLGKIN-
QNCASIITEDFQKPKDVPQAKETLIDKVISSYNIETAHDDSNCNITREHVCICRKNENEP
VSLENSQRDYKETAYVE---DTGQDHSLFCNSQLNNNIC---LNVNFK-EQRDNYKE---
---NQNEAKE-N-NALSEENNLENIYGDEKPGSHTN--ENFSI-VDEKEE-KKNYNIEIL
SSEEFSTTFNLICREK-YVSPETAFLES--EEDTISAMKQKDTE-NTGRRIEHLASTT-F
PEI---ASSSVCVASNAAVQIASATIPALS-TNNEDDQIYQFKETYS-ESSDFGLLVKHR
VSGGEIDMDKNKLQESFHRSIN-EN---LVLQSIELESEIEIGLEDCDDAFV--FQLDTH
SHENMPCEEFVTSYKALKSRITWEGLLALDNGEIEVLECTTGRENSDQHYSKESNHFYSS
AQNNETDLPSPILLPDLQIRIT-NIFRPGFSPTADSLALKDNFCTHTVAATKLEINKE--
----DEETLGFGIYSKPSGENTDYPCEDKVGNI-RQESALVSKA-EISLSFDWS-NNTDV
---NHTSE-NQNSESLFTEPSNVT-AIDDGSGSFSTKSK-TVYNDTKNKKEVESRSNKRK
L-YTSSEDQNIAHKDLRWHEICGKKRRQTSQDSSECFSSLSQGRIKTFSQLEKHIKSVLD
ILRGEASLCKSKRLSRKLDKAVIHLKKAHRRVHTSLQLIAKVGEK-GRGPLPRSYAIICN
NF-WESCDLQGYSSVSQRRYYSTKHFLSKRKYDKQRKKRALKTDISKSLTHVSKYKSYK-
T------SRV--KKCLSRKSMASSVSKTHPI-IHMGEFSNQE-HPELQLPVSSTSQITSQ
S-VYYNSSVSNPSLSEEHQLSSGK-TRSLFSPHHSDEKLIEKENQIDTEFLSSISKYEKL
ENHSANH--K---DATKENSCQINEVINESNSVSSSCIRENNIDYSTGN-DYDATCIDHT
KVKTDVLISVLDSNMEHFLNADLYQQNNLTLSDCKRNLEVNFPVEKCTVPIERSKQNIIT
GNFLMDPLNLTLIASKK-YIIPQLLSAAAVTDSEGESSVSYLDKQRILTIDSFAAST---
---TISNCEQSCRGK--VLLKTEQCSSGNCLHTNGNETNVT-ENYELDVTS-VTEESKS-
-YGENV-------V-KLSSSDSSLLLKDNVKGSSSETCTVKKDTENRIMQKVKQVEKA-K
DSV----YK-SMTE-GSTVKTEYKNRKNQMS-EES-CLNEKMIKTNLIDSHLS-TENTTT
E-SFSLKNTVSNPR

PF15326 // ENSGT00390000006260_0_Domain_1 (2115, 2382)

NKRE-KKGEIKV-SNVSQS---------------------------
-DLTLHSEIACISK---PEILGVNHMPVLPAHSKTCKVTTFL-KKPTSYVSGFKDKHSSA
NHTALIPQLSQILQRADEASSLQILQEETKVCLNILPLFVEAFERKQECSVEQILISREL
LVGQNLWNNWKHILKPCAIDTLVELQMMMETIQFIENKKRRLEGKPTFRSLLWYDETLYA
ELLGKPRGFQQQSNFYPGFQGRLKYDAFCELQTYHDQLVEL

ENSGT00390000006260_0_Linker_1_2 (2382, 2547)

LEETKRENNSYYAFLKYKR
QVNECEAIMKHCSDCFDFSLSVPFACGVNFGDSLEDLEILRKSTLKLISVHG-DSPKVHS
YPGKQDHLWIIIEIISSKINFIKNNEVVGIKISLYGLEHIFFDAAKNLVWKERGQSFSKN
-PPKKDEEGLLTVNKHAFSKLQKIYD

PF15326 // ENSGT00390000006260_0_Domain_2 (2547, 2722)

TLSKDLNNEP-ISSMGLEDTV-IAS--RNHPINK
ATSTIEDCKFNS---TLLAHPDICCISEILDQAEFADLKKLQDLTLRCTDHLEILKKYFQ
MLQDDNIDNIFITEENVLGTVKNHSHAAIILKPEAIEMYIEIVMVSETIHFLKNSIAKKL
DKQRFRGMLWFDLSLLPELVQCQEKMASFSFLKENSTDVCLWKVIETAISELKKDLDIIY
KYNE-AVNCSYALHLISRELQELSEIKKLLKKSEYPTSTYIEFVPYIASINYGSTITELE
YNYNQFSTLLKNIMSAPRKDLGKMAHIMKVMKTIEHMKIICAKNAELTISFILCQMLYNR
RKILQ-LKRKEKLVIHVVKPEENISKSSISV-MIPPVSECLIKNISKSSKQRPGSADKCE
D-SQEQQEN-TVSSCKKLKLDMKDVTKISREKATFKHPRTTGSHPQSEKKIVSSSSNNLK
RNHL-TPKKVEMQRSLPGSL--LENPKDTCTSKSESKIDLT-VS----ERFTGQQENL-T
SMKK--TNVNFSAAETKSDNKDCAAFVICDQKSVYG-TFSPDHETVMQKFLKNSPDPTQK
SCLSDINPGTDVSLVPDT-SVLSKPITCFEKDSHIDSEMN-DRVFKLQDNDIVNSSIKNS
T---CMTSPEPIFIQNKIPTLQINELQPAETESEDKYMKDTLNPNTVHTFGGSGHITVNV
NQTAEYSFSEQQ--NGENSKVLTQNATTYWNELPQSACTPVYNSSENLFG-TSYPYYSWY
VYHYSS--SNGNAITQTYQGITSYEVQP---SSSGLLTTVAN-----TTQSTHSNLLYSQ
YFTYFAREPQANNFVPVNGYCQSQIPAAYNFQQPIFPQY-SHQPLPQATYPYLPNLDVPP
EDPWTYTPWH-QQSFHPGH--

--------MATNKMEMKEIAKNKTLWKMNSV----SEPLLVTGVEVNPLKKFTIPKIRRT
AEKVYLSPCCTNTREYSFIHDTLNQCQLDVDCDLQS-SWQFGDTKL

PF12509 // ENSGT00390000006260_0_Domain_0 (107, 279)

VHNEDLEKNFTSKR
SEMRESGRHGRELEEHFCFLALSQNDVAEIYQNGISTRT--STLKILGNPLLGTYMFRHV
DVALNYAHSRSITVESIIIFKV-LFGKVK------KIQPSVCKNKVSLDPSPNFDCHMSR
SVPSLKDTIE-LQAYNSAVYFYEYNVLSKPVDKPRQCL

ENSGT00390000006260_0_Linker_0_1 (279, 2112)

PYAIVTVKFIGQKIDNGHLMTS
LRFLSSGFPKRAERTCSLNNCTVAKRIGKGKDATVIFEHFRKPVDPF---VPENCSCSVL
NAEINPSNANISNTYGNVQNG-NISIHETYNGQKEHNLAECRDMSQVHICDSSLSFIPSG
TRESV-NGDLMLNLTHFTNVLSGLSAAFPLRNNTGSSTVITSKLIKDPRLMRREESIEKH
NNIAGLNEILPLEKSLDFVNSGIN-LSSMPSNSASSSEIVAGDHSVLTSCLDTPCFKISL
DNSQSQAHNLDFQSYNYTTPNK--MAGQCKGQ---D-NFSSPMCLPNIVSEVENQKHSEG
EVQRSQQRSNIPLLIEEKDEPHN---------SYESV---NTCIRGYSTHISQKSWSSNS
ETVCQTGQQMS-TVFPLQRKEN-IDGYIQNIEKMRDF-TDPEDNS--RHGEKQILWKET-
------EAKISPIDNYISLYQE--CKGDESHDSFGKNSDQILITQEL-EIPK-SSTSATK
DKYKLDHLALELQSNLT-PRTETLSQKHPQPSLEYED-NIHTSFAVSQKLMELKLEKPN-
ENCVNIMTNAFQEAKDIPQAKELPIDGVISSHDVKTTHDNSNCSVSREHIYVHRKNENDR
MSLENMQRDCKVTFQIA---DKGQSHTLSCNAELHNDIH---LNIDFK-EQGDHDKE---
---NENETKEEN-TALSTENNRVDICGHEKQGSHTN--KNYAN-IDER-KNKNYNNVEIL
SSEEFC-TFNLTGGEK-CISTEATFLDS---ENTVTAIKQKDTQ-NTGRSVEHLTSIT-F
PQI---AESSVHVASNAAVQIAGSMVPTLG-TNHEDHQRYQIKEACSSESLDFGLLVKHK
VYDCEMDIDDNKLHESFHQSIS-DS---SVLQSFEVENKIEVGSEQCNDAFL--IQQDPP
SHGNVLYEEFRASFEALKSRIDWEGLLGSNNGEREVLKSSKRRENNDQRYSEKSNCLYSS
IQKNKAELCHPILLPDLQVRIT-NIFLPGFSPTSESLALKDKFCKNITKTTEPEINK---
----EGKVPGFEMYSQCSGENSGYSLEDEFGNT-RQESGLVSKS-EISHSLDVN-HNTQG
---NHASE-KQNSGPLLSEPSNVT-TLNNESRYSLTKSK-TNCNDTRSKKDTESKISKRK
P-RVPFKDENMAHKDLRNHEIYGKRRRLTSQDSFECFSSLSQGRIKTFSKSEKHIKSVLD
ILNTEASLCKSKRLSRKLDRAVLHLKKAHRRVHTSLQLIAKVGEK-RKGPLPKSYAIICN
NF-WESCDLQGYSSVSERRYYSTKHFLSKRKYDKPREKRALGFEMDKSLTPVSKHKSYQ-
A------SRERITECLSNTNVASSVS-SHTT-VHVREFCDQE-YPESQLTLCSTPQSTSW
S-TYNKSSMRS-LRSSELQTFSGK-TGCLFSPPCPDEKLTKKENQIGIKFLSNISKYEKP
GSHSANHKIK---DTMKESHSETNKVINKSNSVSLSNIKENNVSFSRDK-NYDATCITHT
KVKTDIVISVLESNVKHFLNVDIYKPDNLILSGYKGNLEVNFPMEEWTAPNQSSKPGIIT
EDFLMDPLNLTLISHKKYNSVPQLLPTTPVTDNEVESSESYLDKQRIFAKDSFATST---
---NVPNCQPECGGK--EFLKAEQCSSSHCFHIDGNESNVL-ENPKLGLKS-VTEEGKS-
-YRKNT-------MKRLFFNDSSLPLKDNVKDSSSKKCMAKTDIQARTMWKTKQAEKA-K
DSL----HRKSLTE-GSIAKTEYKNQKNKTL-EESSYLGEKRIRNNVIDSHLS-IEDITE
A-VVSLNNPIS

PF15326 // ENSGT00390000006260_0_Domain_1 (2112, 2382)

NHLSKRE-KEGGVKV-GNDSHS---------------------------
-DSALHSEIACNSK---PGIIRMNHGPALHRHSQTSQPSTPQ-KMTTSNMNGLKEKHCSA
NHSALIARLIQILRRADETSSLQILQEETKACQNILPLFVEAFERKQECSLEQILISREL
LVEQNLWKNCKHKLKPCAIDSLVELQMMMETIQFIENKKRVLGGEPTFRSLLWYDETLYG
ELLGRPRGFQQQSNFYPAFQGRLKYNAFCELQNYHDQLIEL

ENSGT00390000006260_0_Linker_1_2 (2382, 2550)

FEESKRENNSYYAFLKYKR
QINECEAIMKHCSDCFDFSLSVPFTCGVNFGDSLGDLEILRKSTLNLIGMYG-DSPKVDS
CPGKQDHLWIIIEMISSKVNFIKNNEAVNIKISLYGLEHIFFDAAKSLVWKERRQSFCKN
YSGNKNKEMLLKMNQYAFSKLKNIYDMLS

PF15326 // ENSGT00390000006260_0_Domain_2 (2550, 2721)

KDLSSEQ-ISSIELEN-TEITSRASDDLINK
ATVNIENCRFNS---TLPSHPDFCCISEILDQAEFADSKKLQELTLRCTEHLEILKKYFQ
MVQEENIDNIFITEENVLDMVKNHNHGAIILKPAAIETYIEIVMLSETVHFLKNTMAKNL
DKQRFRGMLWFDLSLLPELICCQEKMTCFSFLKDNSTD-CLWKVIETAISELKKDLDIIY
KYDE-AVNCSYALHLLSRELEELSEIKKLLKKSEYSVSTYIDFVPYIASINYGSTMTELE
YNYNQFSTLLKNLMAAPQKDLGKMAHIMKVMKTIEHMKIICAKNAELTISFILCQMLHNR
KKTFP-LKRKEKINTHV-KPRKSTNKSSTFM-KVPSISECIMKNVSNSSRKRSTTVDQCE
D-SQEQEKNTTVFNCKKQKIDMKDVTKVDKEKTTFKHPRTTRSHPESESEIGPSSSDNLK
RHHV-SPKKVEVERSLPGSVLPLKNLKDICTSKSEGKIYVTNTSPDTSEDFTGQQGNL-N
SMKK--SNVNFSATET-SDKKDCSSFAICEQRSVDGRIFPKDCRMPSQRFL----TPAEK
SCPSDIKPGTDASPLPDA-SVLSNPIFHFIGDIPANLGMNDDTVFELQDNEILNSSIKNS
A---CTNATEPKLTQNKSPILHVNKTQPAKTELKEKYMKDTLSPSII-PVEASENLTLNV
NQTAEYSFSEQQ--NNENSKVLTQNAAAYWNELPRSACTPIYNSSEHSFG-TSYPYHAWC
VYHYSS--SGSSSLTQTYRGITSYEVQA---PPSGMLTAIAS-----TVQNTHPNLLYSQ
YFGYFAGEPQANNFVPVDGYFQSQVPVSYNFQQPIFSQYAPHQPFQQAVYPYPPNSGVLP
EAPWTYVPCQ-QEPFQPGH--

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------TVCSLNNCTVAKRIGKGKDATVIFEHFRKPLDPF---VQENCSCKAP
NSEINPSNSDTSNSYRNVKNG-NNSVLEVYRRQTDN-SLEIRDTSQVHVPDSSLSFMSGD
NRESG-TGDLLFNVAYLKSILSSISAAFPSQKNTGSSTVITSKLIKDPRLMKREQSIGRQ
NNSTDLSDMLPFDKSLHHGNSEIS-LSCVSTSSVFSPEVVPGNHAA-STCLGTPSFKFSF
ESSQFQTHNMCSKGYDCIAASKTPMTEQCKEQ---L-NFSFPISLSNAVPEVENQKYIEE
KSLSIQNRSNIPVLANESSDPQN---------SYESA---KACRKESESHISQES-----
--------QSS-TVFPLQQKGN-IDEYIQSIGKMRTF-SAPEDSS--KHGESQNWQKETN
N--FTNQTKIIPTDNCITLYQE--YKEGGNLNSLGGNCEKILKTQGL-KISQ-SPESTTK
NKDELDHVILDLECNLT-PEIECLSQKHHQCSLGYED-SICTNFAVAQN-PELKLVQKT-
QNFVNM-TGNFQETKDTLPAKEQLTDSVISSSAVDIPLDSSNCSITGEYICVQRKNENDP
VSSENIQKDCNETPQIK----DVRDHSLLYNAELNCDLH---FSK-FK-GQGD--KE---
---NPYEAKDKYK----------SLNGSERQDFHAN--L-FTN-VV-EREIKNYNKVEID
NSEDIS-TFNSILEKK-SIPAETALPES---EHSVTAI-KRHAQ-NDVRSVEHLASI--I
PEI---TGSSVFVAENTTKQAASTTVLTPS-TN---HEKYQFKETCSSEISDWGL-IEHN
VSDCEHSMDKNKLEESLDPSVN-EN---SVLQTFELGTEIEIESEECNN-SL--FQQDTH
THGNAVHEELE-LYEDLKSRIDWKGLFLNINEEMETLGSFARREKSDQHHATESNCVSLS
-QKNESELHNPILLPDVQITIT-NVLKLGFSPTGDSLELKDNFYEHFTKSAELEGRKE--
-----GKSPGFCIYSQPSGEKSVFPCENKFGNS-IQELGLGRISSSISHSSNLD-HNTCV
---NHTYE-KSVNQTFSTKPSDVT-ILNGESKLSSTKSK-PRFNDTGN-KNMESRSSKRK
LYT--PGGQNRPQRDLRQHETYEKRRKLTSHDSSEHFSSLSQGRLKTFSQSERHIKSVLD
ILSSEASLCKSKRLSRKLDKAVLHLKKAHRKVHTSLKLISKVGKK-RKGPLPKAYAVICN
NF-WESCDLQGDSFMSERRY--SKHFLYKRKYEKQGEQRFFGFDIDESVVQVSKRKPSR-
T------DRASVAECLSSEILSRSVSSSLAT-FHVREFCDEEQHPES---LAYPSQSTNQ
S-EYSNGIMKN-ARSSKLEHFVET-NECMLY---PDEALAEKEHQTDTKLP--NSDFSKL
ENSSAHD-IK---DRTKENNSQPNVMVYKSNSASLNYIKENNIGYSPDK-NDDASYKAD-
---TDILASVLDSNMNHFLNVDIYQQDNLPVSICKRKLESIFPVGKYTVPIEIV--T---
----PNPLNL--IASKR-YNIPQL-SSVLVTAGEEESSKFYLRRQGI-------------
------------------------------FAIDSFASYPT-T---SYYSQ-MCGG-KD-
-LLKT--------K-QYFSSNCFLIDENEVNVT--ERSILALTSVTEEMRKTEQAV----
-------YKSI-NE-GSTVDNEYQSQKNKIP-KDC--LMKKIVKSNLLR-----------
---------------------------SNDS

PF15326 // ENSGT00390000006260_0_Domain_1 (2132, 2381)

YS---------------------------
-D--------YIYT---PAIVGIKHKPILYAYPDTSK---------------EIEEHCLP
NCTSHIAELSRILQRADEAASLRILEEETKICQHILPLFVKAFERKQECSLEQILISREL
LVDQNLWNNYRLKLKPCAVDTLVELQMIMETIQFIENKKRLLEGEPTFRSLLWYDETLYS
ELLCRPRGFQLQSNFYPAFQGRLKYNALCELKNYHNQLVK

ENSGT00390000006260_0_Linker_1_2 (2381, 2536)

YFAKIKKE-NSYYAFLKYKR
QINECEAVMKNYSDCFDFCLSVPFTCGVNFGDSLGDLETLRKTTLKLISIYG-NSPKVLS
YPGKNDHLWIIIEMISSKVNFIKSNEEVNIKISLYGLEHICFDAAKNLVWKEKSHSFPKK
QSQK-NKTLLLKFNK

PF15326 // ENSGT00390000006260_0_Domain_2 (2536, 2721)

CAFSKLQKIYDTLSKNLNNEP-VSNIGLEENALIASRKSA-LA--
---IIENFKFNK---TLLSYPDICCVSEILDQAKSADLKKLHNLTLRCTDHLEILKKYFQ
LLQEDNIDNIFVTEENVLDML-NSNHGAVVLKPEAIEIYIEIVMLSETIHFLKNLIAKKL
DNQRFRGMLWFDLSLLPELVHCQEEMSFFLF-NDNPAD-GLWKVIETTISELTKELNVIC
EYDE-AVNCSYALHLFSRELKELTEIKKLLKESKYSVSTYIDFVPHIATINYGNTVTQLE
HNYNQFSILLKNIMSVPQKDLGKMSHIVKVMRTIEQMKIISAKDAKSSTRFILFQMLRNR
WNTFQ-LDRKEKMNTRVTKPEENSSQPGISVVQAPSISECIIKNISKSSKKRPITVDKCE
D-SWEKENIAAVSSCKKQKVTMKAVTETDRQKTTFKHPRTTGSHPKDENKIRSSSSDILK
RNSV-SLEMVKKQNSIPGSLLPLKNLQDICTSKSESKIDLASSLSDTLGYLAGQQENL-N
SIKK--RNVNFSIAETT--DKDC-PFVPCNQKNIDG-IYSEDHSTLSQKRHKNPMEQTRE
ICSPNIKAGIDDFLAPNA-SMFSVPSS--------RLEVT-NTDFEHENSEVLDLSIKDY
T---HTNSPEPVIIQDKIPARQVDTTQAVKPELLGKYVKNTSNPSSA-PFGSSGSSTPNT
AQTMQYSLSEQD---KENSKALTQKADTYWNELPQSACTPVYNSSEHSFG-TSYPHHAWY
VHHYNS--NNGNTMTHTYQRMTMYEVQ-P--PPPGMLTSVAR-----SVQNTHSTVLYSE
YFSYFAEQPEANVFIPGNGYIPSHVPNSYNYQQPIFSPFVPCQPSPQTAYPYPPNPNWLP
EVPWTYAPWQ-QEPFPPRH--

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--MTYFFIYVSTERACSLNNCTIAKRIGKGKDATVIFEHFRKPVDPF---VQENCPCKAL
NSEMGPFSSDTSSSYGNVQNG-NNSVIEAYNRQTEN-SSNLRDASQVYTHNSGFSFIPTG
NTASG-NGDL-FSVTYLRSILSSISAAFPSHNNTGSSTVITSKLIKDPRLMKREQSMRNK
SDTAGLSDVLPLDKSLGCGDSQIK-LTCMPTSSISSSE-VPADHTI-TSCLNASCFKFSS
ESSHYQAHNSSSKGHDCIASSSIAVTEQFKEQ---H-SSSFPSSLSNAFSDVRKQ-HSEE
QVQRAQMRCNVPVLTALSSELWN---------SNE---SENTCSNDSQGHFSQESPSSDI
NSIYKVGHQMS-TVFPAQKKGN-LCEYIQDTGMMRAS-ISTEDST--KDGVNHTWCKETV
---LTNETVSSPIDNSNTLYQE--HKEGGNLNSLSGNCEKIGVTHKL-QVPK-FPISSTG
DKDELYRAALELECSLT-PTLECLSQKYPQHSLEHED-N--TNFAMTQGLIELKTVQNN-
QNFGNILSDAFQEAKDVPLASEKLIDRVISSAAIDISLDSSVCNIVGEYTCVQRENENGE
ASPYNCHKE--EAAHVK---DGVQDHSLSYDAELSCDLN---LKINLQ-EQRD--DK---
---NPNEAKE---------HNTDNINGSEKQDCLAN--DHFTN-IVEMREIKSNTKVEIL
NSEECF-TFNSFQGKN-GKPAETASSES---E----AVEQRHAP-NDQRGLEHLVST--F
PEI---EGSSVCVASNATKQTVGTTVLTVS-TSLGDHQKDELKEICSSESSDLGL-VKHS
ISECEIDTDKDKLQD-FHQLVN-EN---SALK-TGLGSEIEVDLEH-DNASV--FQQNMH
SQGNDLCEEFE-LYESLKSRIDWEGLFGSSYEEIESSSFARR-EGTDQHSSTDCNCVSFC
SQ-DKRELHNPIFLPDLQVTIT-NLLSLRISPTDESLELKDNFYKQVTESTEPETNKE--
-----GNASGFGMCSQPSGENSSFSCANKFGNS-VQESGDVSKS-ESSHSSNSS-HNTHV
---DQGSG-KPNNDSLSTEPSNVT-VTNDKSKC-PTKSK-PVFNDTRNKKDMQSRSSKRT
LHASSSRGQNIANKDLREHETHEKKRRPTSHGSSDRFSSLSQGRIKTFSQSEKHIRNVLN
ILNNEASLCKSKHLSRKLNKAVLHLKKAHRRVHTSLQLISKVGQK-RKGPLPKAYAVIHN
NF-WESCDHQGDSLMSERRY--SKHFLSKRKYDRQGDKRFLRFDIEESLTPVSKHRLYR-
T------NRERIAECLSNEVMSGHVSSSLTT-FHVREFCDEEQFPEPQLPLAYTSQSISQ
L-EYTNSIVGN-ESSSELEHFSET-SGNMLD---PKETLTEKEYQTHTQLC--NSDSAKL
KNHTTHS-IR---DIAKECNSEDKTVLCESNPVYLSFIKEN-TSHSPDK-SYDSNCKAN-
---TDIHISVLGSKKKHILSVDIYEQDNCVS-DGVKSGEAIFPIEKCTFPMETT--S---
----SIPTEN--IASKS-YTIPPV-SSILVTAGEEESSVG---ENGL-------------
------------------------------FDVNENEMNIT-VHSKLDLTS-VTEESKI-
-CKKNM-------K-NLSCNDSSILLKENITGP--SKRYMAKYIEEEKIRKIEQAV----
-------YKKIITE-GSPISFKYKSQNKILK-EESFHVNKKIITNNLTDSHLS-IKNSTV
D-TIALKDIPN-Q

PF15326 // ENSGT00390000006260_0_Domain_1 (2114, 2381)

LKERK-EAGQIKV-NNNSHS---------------------------
-D--------CLSK---PAIVETNHRPVLHGNPKVATL-----QKE-------LKEHRSP
NYTSHVTELSQILQRADEAASLQILEEETKLCQNILPLFVQAFERQQECSIDQILISRKL
LVEQNLWNNCRLKLKPCAVDTWVELQMAMETIQFIENKKRFLEGKPTFRSLLWYDESLYS
ELLRRPRGYQLQSNFYPGFQGRLKYNAFCELQNYHNQLVE

ENSGT00390000006260_0_Linker_1_2 (2381, 2587)

FLTETKKENNSYYALLKYKR
QINECEAIMKHYSDCFDFCLSVPFACGVNFGDSLGDLETLRKSTLKLISVPG-GSPKVHS
YPGKKDHLWIIIEIVSSKVSFIKSNEEISIKICLYGLEHIYFDAAKSLVWKEKSCSLPKK
HSEK-NRE-MEEINESAFSKLKKIYDVLSKGLNNEP--TSIGLQEDAIIASKQST-VG--
---SIS

PF15326 // ENSGT00390000006260_0_Domain_2 (2587, 2721)

NCRLNK---AWLSYPDISCVGEILDQAKSADLEELQGLTLRCTDHLEILKKYFQ
MLQEDNINNIFIMEENVLDMLSNHNLGAVILKPEAIEIYIEIVMISETIHYLKNLIAKKL
HNQRFRGMLWFDWSLLPELIGCQEEVVSLSV-GDTQTH-CLWKLVETAISVLKKELAVIY
EYGE-ASNCSYALHLFYRELKELTGVKRLLNNSKYSVSTYIDLVPHTASVNFGNTVAELE
HNYKQFFLLLKNVMSVPQKDFGKMVHIIKVMKTIEHMKLLSAKDSKLSTHLLFLQMLRNK
RNALQ-QNRQEKMETPVTEPGEDSSQPGVSE-QTPPGAECTVKNISDSSKKRPVTADTCE
V-SQGKGNTDTVPSWKKQKVTMKDVG--NIQ-TVSKHPSTTGSPPNDENKIGSNSSDSLK
SISA-SPEVVKRQSSVLGSVSPAESVQDTCTPKSESKVEPTDSSPDSLASLTEQQENS-N
VIEK--RNGNSSVAETN-DKKDC-PLVTCDQKDIDA-SYSPDHTP-AQKSHKTPVDH-TQ
ISPSNLIAGNDDPLVPDA-SLLSVSASQSEKDVY----LS-GTDFHHENNKILNLSTEDC
T---GTSSPEPVCIKDKISVLQVDKTQPIKSESPKKSMTDAPNPNTA-PFGSYGNSALNV
NGTVQHTHSEQ------NSKVLTQKVGTSRNIPPQSACSPVHNSSAHSFG-TSHPYYSWC
FYQYSS--SNGTAVTHTYQGMTAYEIQQP--P-PPVLTTVAS-----TVQSTHFNRSYSE
HFSYFPGQPQANSFNPGNGYFPSRTPVSYNYQQPVYSQFASHQPVPQATYPYPPNPGAPP
QVPWTYAPWQ-QNPFLRRP--

--------LATKKMEMKEIVNHKTLWKMSST----SESSLITGMEVNPLKKFTIPKIRRA
AEKVYLSSCCTDTREYGFIHDTLNQCRLNVSCDLQL-SWQFGDTKLVHNEELEKNFTTKR
S

PF12509 // ENSGT00390000006260_0_Domain_0 (122, 279)

EMRESGRHSREFEEHFCFLALSQRDAAEIYQNGISTGA--STLKILGNPLLGTYIFRHV
DVALNYAHSQSITVESIMLFKV-LFGRVK------KVQPSVDKNKVSLDPSPNFDCHMSR
SIPSLKDTIE-LQAYSSAVYFYEYDDLSKPVEKPRQCL

ENSGT00390000006260_0_Linker_0_1 (279, 2115)

PYAVVTVRFIGLKVDNGQLMTS
LRFLSTGFPKRAERTCSLSNCTVAKRIGKGKDATVIFEHFRKPVDPF---VQENCSCDEL
NSEINPSNSDVSNSYRNVQNG-NISILETYSGQTEHNLAEITDTSQVYAHDSGLSFMASD
TKESV-NDDLLINLTYLKNVLSSVSDALPLH-NIGSTTVITSKIIKDPRLMRREESMGKQ
NNSPGLNEILPFEKSLDYVNSEIN-LPPVPTNSPS-SGVIPDDHTVLTNCSDAPCFKISF
DDSLSQ--SMGSKDYVCTVPNNITMEGQCKDQ---D-NFSFPISLSNVVSEVENEKHSEK
KAS-------------------------------KRM---NAYTNEYNDHISQESQFSNS
ETVYQTDNQIS-IPFPLQNKAS-IDEYIQNIGKMSNC-TDPEDNS--KHGEKQTLWKEID
N-EFTNETKISPIDNCISSHQK--NKEGDSLDYLRKNCDKVLITEEL-EIPK-SSTSATK
DKDELDHLTLELQ--IT-PGVESLLQKHPQYSTEYEN-NIHTSFAIAQKLMEPKLKKIN-
QNCVSIMNNAFQEAKDTPRTKEMIIDTVISSHDIETARDNSNCHITREHMCIHRKNENKP
VSLENIQRDCKESLYIG---NEDEDHTLFCNAQLNNDTC---LSVNFK-EQRGNEKE---
---SQNEAKEED-RALSPENNIENIYEDKKH-------NNFTN-KDERRENRNYNNVDLL
SIEEFS-TFNLIWGEK-CISTETALLEN---ENTISAIKQKDTE-NTGRSVEQLASIT-F
PKI---ASSSVSTVSNAAVQTA-STMPTLI-INHEDHQRNHFKVTCSSECRDFGLLVKHR
TSDCEIDMNKSNLQESFHQSI--NN---SVPQNFELGSEIEVETEECDDAFL--FQQDAY
SHGSVLYEEIEALYEALKSRINWKDLSGSNNGDMGVLESTTRRENN-QHDSEEGNYVNSS
TQRNETELLNSALLPDLQIQIT-SIFRPEFSPTADSPAFKDN-YTCVTEATKPETNKE--
----GE-ALGFEI-SQPFGENSNDPCEDKIGNI-RQGSELVSKN-EISLSFDLS-HNAHV
---TQMSE-NQNSESLCTEPPYVT-PINDRSRCSFTKSK-SDCDDTKSKKEKESRISKRK
L-HTSSRAENISLKDLKQYKIYGKKRRLASQNSSECFSSLSQGRIKTFSQSEKHIRSVLD
ILNSEASLCKSKCLSRKLDKAVIHLKKAHRRVHTSLQLITKVGEK-RKGPLPKSYAIICN
NF-WESCDLQGYSSVSQRK-HPTEHFLSKRNHDKQGEKRTLSFVGAKSSTHVSKHKSYK-
T------NEEKITNCLSKKSMASSVSKSHST-IQEREFCDQKQHPESQLPLSSTSQSTSL
S-AY-NNSMRN-PQSSELLPFSRK-TGFLLSPNCLDEKLIEKENQINIKFSSNINKCEKL
ENHSAHNNIK---DAAKENSYETDEVINESNSGSLSCIKEN-TSYNSDK-SYDATCIPCT
EVKTDLLISVLESNVEHLLNVDIYQQDNLILSGCERNPNWTAPTE-------SSKRSAIT
GKLFMNPLTLTLLAGKK-YSIPPLLSVTEVTDTEDKSSKSYLDKQRMFTVDSVEAS----
---TVSHYQQRCGGK--ELLRTEQCSSINCFHTGGNEANTT-ENSELNLAS-ITEKSKS-
-YGENI-------M-KLASDGSSLLLKDHIKGSASKKHIVKKDIQDRKMWKIKQAEKA-K
DFI----YKRSMTE-S-TVETEYKNQENKIL-EKSFHLNEKTIKNNLIDSHVS-IKNTTK
A--VSLNNTVSNQL

PF15326 // ENSGT00390000006260_0_Domain_1 (2115, 2382)

NKYE-KKEKIKV-SNDPKS---------------------------
-DSTLHSEIACISK---PDLLRVNHMPVLHAHSKTSKVSALP-KKLTSYISESKEKHCSD
NQTALIAKLSQILRRADEASSLPILQEETKVCQNLLPLFVEAFERKQESSVEQILVSREL
LVDQNLWNNYKHKLKPSAVDTLVELQMMMETIQFIENKKRLLEGEPTFRSLLWYDETLYA
ELLGRPRGFQQQSNFYPAFQGRLKYNAFCELQIYHDQLIEL

ENSGT00390000006260_0_Linker_1_2 (2382, 2539)

FEETERENNSYYAFLKYKR
QINECEAIMKRCCDCFDFSLSVPFTCGVNFGDSLGDLETLRKSTLQLISIHA-DAPKVHS
DPGKQDHLWIIIEMISSKVNFIKSNEAVSIKISLYGLEHIFFDAAKNLVWKERRQSFNKK
HSQK-NKEMLLKINQCAF

PF15326 // ENSGT00390000006260_0_Domain_2 (2539, 2722)

SKLQTIYDTLSKDLNSEP-VSNIELEEDTMIASGKVDHLTNK
ATSGIENCRFNS---TLFSHPDICCISEILDQAEFADLNRLQDLTLRCTDHLEMLKKYFQ
MLQEDNIDNIFITEENVLDMMKNHNHGSVILKPEAIEIYIEVVMVSETVHFLKNLIAKKL
DKQRLRGMLWFDLSLLPELVHCQEKMTSFSFLKGNTTNVCLWKMIESAISELNKDLDIIY
KYDE-AVNSSYALHLLSRELEELTEIKKLLKKSKYSISTYIDFVPCIASINYGSTVTELE
YNYNQFSTLLKNIMSAPQKDLGKMAHIMKVMKTIEHMKIICAKNAKLTISFILCQMLCNR
RKAAQ-LNRKEKMDFHVIKPGENISKSSMSM-KVPSTSESIIKNVSDSSKKRHITLDKCE
D-SQEQEKNTTISSSKKPKMNVENATKINREKTAFEHPRNTVSYPRSENKIASSLSDDLK
RNYV-SPKAIEMQ-----RSLPLKNLKDTCTSKSESKTGLTYISSDTSEHFTGQLGNL-N
NMKE--KNVNWSAAETKSGNKDCAAFVICDQKSVDG-TFSTNPETPSQNFIKKSLHPIQK
SCLSGTEPGMNTSLVPHV-SLPSKSVFHFVRDRHTSLEMN-DTVFELQDSEIVNSSIKKP
T---CMTSPKPIFVQNEIPVLQINKTQPAKMESEGKYVTDTLNPNII-PCGGSGHITLNV
NQTAEYSLSEQE--DDENSKVPTQNAATYWNELPQSACTSVYNSSEHSFG-ASYPYYAWC
VYHYSS--SNGRALTQTYQGITSYDVQP---PPSGMLTTVSS-----TVQSTHSNLLYSQ
YFSYFAGESQANGFVPMNRYFPSQMPVSYNFQQPIFSQYAFQQPFPQAAYPYPPNSGVLP
EVPWIYAPWQ-QESFQPRH--

--------MATSKRKMKKISK-HMTWKMSSN----KEPLPTTGEEVSRLKKFTIPKIRRT
AGKVYSSPCGTNTREYSFIHETLNQCRLDVSCDLQSSSWQFGDTKLVHNEELEKNFTAKR
S

PF12509 // ENSGT00390000006260_0_Domain_0 (122, 279)

EMRELGRHGRELEEHFCFLALPYRNVVEIYQNGLSTKA--STLKILGNPHLGIYTFRHV
DIALNYACNQSITVESIIIFKV-LFGKVK------KIQPSMDINKVSLDPSPNFDCHMSR
SVPSLKDSIE-LQAYNSVVYFYEYSAFSKPVDKPRQCL

ENSGT00390000006260_0_Linker_0_1 (279, 2114)

PYAIITVKFIGQKMDNGHLKTT
LRFLTTGFPKKPERTCSLNNCTVAKRIGKGKHATVIFEHFGKPVDPF---APENCSCNTQ
NSEINSFNANVSDSSENVQNG-NVSILETVSGQTENSSAESTNISQGHVHDSG-PFMSSD
NKENGNNGY--LFSTYLKNILSVISSYFPLYKNIDSSTVTTSKFIKDPRLMKREESMGKQ
NNTTGFSEVLPVENNLNS-NSEIN-LSGVSTNFVSSSEVVPSDSATLSDCLDTPCSRFSF
DDSPSPTHNMDPKDYHSVASNKITRVRQSKDQ---G-HFSSPLSLLNV-SELENQKHTEE
KAKTAQERSNIPQ----SSKAHS---------SYESV---NTYTKDSDSQISKELHSSNF
ASTYQIGHHMS-AVFPLQMEES-VDECIQNIGKIRNF-TDPEDSY--RYEEKPILENE-T
D-NFTDATKITPINNYISSHQE--YKDDETLDSLGGNSDEILITQEL-EMPK-SLTSTME
DKNEQGHLALDLESNLT-LNIECLSQEHPQHSMDCED-SIHTSFVFTQKLREINLEKRN-
ENCISIITDPFQEAKDISQTGELFADSISPFHGIEITFDN-----SREYVCVQRKNENES
L-LEDIQRNCKEIPYVE---DEGEAHFLSRNAQLNDSRY---LTLHFK-GQGDNDKE---
---NKNK--EDD-RTSFPKDNMEKIYECKKQEYPTK--NTFTN-IG-WKKNKNDNKVEII
SSKDIPTTFNFIWGKK-DMSPETALLED---KDILAAKKQRDVQ-NPGRSVDYLTFTS-F
PKM---ADYSVGVTSSSAVELAATTLPALS-ANHEAQQRYQFKETCSSESPDFESLVKHK
IADCEIDADKNKLQDSFHQPIN-EN---SLLQNFGLGSEIEVELEECDDAFL--FQQNRH
SHENVLDEECEASYEALKSHIDWEGLFGSSNGKVDNLGST-VRQNIDQQHSKNTICFCS-
TYKK---EVYPILFPDLHVRIT-NTFTSTFSPADDTLSVKDNFYKCLTEAPKPGINGG--
------EAPGFDIYSKS-CENSSYPCTDQFGNS-MQDSGLLSKS-EIFHSSDIS-NNTAV
---NHKSG-KKNNDSLSIEPSNVT-TINGDQKCFFTESK-TDFNDTRNKKDMESRISKKY
I-RTSFRDQNISHKDLRQREICEKEKGLTSHDSSECFSSLSQGRLKIFSQSERHIRGVLN
ILNSEASLCKSKRLSRKLNRAVLHLKKAHRRVHTSLQLIAKVGEK-RKGPLPKAYEITCN
NF-WESCDLQGYSSVSERKY--SKRFLSKRKYDKIG--KVFGFDVNQS-TCISKYKSYK-
T------NGERIAVCHSKKNVTSSGSRSHTT-V-HREFCNQH--S-SQLSLFSTSQGTSQ
P-DFDS-SMKD-SRTSELKHFSGK-SEYLLY---SEEKQSEKENQIDTK-LSD-SKCGKL
RDHSHNKDVT------KKNNSEVNKIVSKSSSISLSGTKDNSVSYSTDK-N-DATYIPHT
EVKTDIFVSTLDSNMKSFLNVDTYKGNDCIISGFQSNLKVNFPIEKWITPTESYKASIIT
GKFLVGPLNLTLISSKK-YNILQL-LTSPVTDSERESSKSCLSKRRILAIDYSATPT---
---TMSHCQQIYNGK--DLLKTQQSS--SSLCVEGNETHVT-EHSELDLTS-VTRESKR-
-YGKNI-------MKKLSFKDSSLLLKDNIKDL-TKKNIAKKDTRNRKTRKIEQTEKA-K
DSF----YQ-NMTE-GSIFKIEHKNQKI---------LKEKSVKSDLMDSHLS-IKTTPE
A--VSLNNTVSSQ

PF15326 // ENSGT00390000006260_0_Domain_1 (2114, 2382)

HKKRK-RKGKRKV-SNDCQS---------------------------
-G--------CISK---PGILEIDHMPILHAHAETSKV-TIQ--KPTSYENEFKENLCSV
THTALITELSQILQRADEASSLEILEKETKACQNILPLFVEAFERKQECSLEQILISREL
LVEQNLWNNCKYKLKPCAIDTLVELQMVMEAIQFIENKKRLLEGEPTFRSLLWYDETLYS
ELLGRPRGYQLQSSFYPAFQGRLKYNAFCELQNYHNQLIEL

ENSGT00390000006260_0_Linker_1_2 (2382, 2599)

FTETKRENNSYYAVLKYRR
QINECEAIMKHCSDCFDFSLSVPFTCGVNFGDSLGDLEILRKSTLKLISIYG-DSPTVHS
YPGKQDHLWIIIEMISSKVNFIKSNEAISIKVSLYGLEHICFDAAKNLVWKEKRQSFCEK
YSKK-NKEVIHKVNKCALSKLQKIYDNLSENLNKET-ASSIELKENTVITSRKSDNLI--
---TIENFRL-S---TLF

PF15326 // ENSGT00390000006260_0_Domain_2 (2599, 2720)

SQPDICCIGEILDQAEFADLKKLQDLTLVCTDHLETLKKCFQ
MLQEDNIDDIFITEGNVLYMLKNHNHGAVILKPEATETYIEIAMLSETVHYLKNSMAKKL
DNQRFRGMLWFDLSLLPDLVCCQEKMVSFSFLEDNPGD-CLWKAVESGISECKKDIDIIY
KYNE-AVNCSYALHLFSRELKELSEIKKLLKKSEYPISTYIDFVPYIMSINYGNTVTELE
QNYSRFSTLLKNIMSVPQKDLGKMAHIMKVMKTIEHMKIICAKNAKLTTSFILCQILHNK
RNNFQ-LKKKEKTNIHFAIPEENT-RPSTSP-KVPSTSVYLIKNISHSSKRRPSALDKCE
D-SQEKGKN-TISSCKKRKVNMDNISKINEEKAVFRCLRTTGFHPKSENKIGSSSSDNLK
RNYV-SPKWDEVQRSLSDSLSPLKNVQDTCTSESQSKIDLTNSPSDTSKHLIEQQENL-N
SIKK--RNVNFGAPETKSYKKDCASFANCDPKSING-ILSKDQEIPSRKLLKNLPDPAQK
TCLSNIKPAADDSLVTNT-SVSSEPISHSVRDVHTNLEIN-GIVLEHRDNELLDSSINNS
T---CASFPESVHIHSRIP--------------------DTLSPSPI-PFGASGSLTPDT
NQTAEYSFSQQQ--DEDNPKVLTQKAATSWSELPQSAYTPVYNSSSHSLE---TPYYAWC
IYHYSS--SNGNAVTHTYQGITSYQAQS---PPSEILTTLTS-----TVQNTPSNLLYSQ
YFSYFADQPQANAFVPVNGYFQSQMPPTYHLQQPVVSQYSSYQPLPQAVYPYPPASGVLP
ESPWIYAPRQ-QESFQPRH--

--------MATNKMEMKETAKQNTLWQMSST----SEPMLNTR-EVNPLKKFTIPKIRRT
AEKVYLSPCYTNSREYSFIHDTLNQCRLDVSCDLQS-LWQFGDTKLVHNEELEKNFTTKR
S

PF12509 // ENSGT00390000006260_0_Domain_0 (122, 279)

EMRESGRHCRELEEHFCFLALPQSDVAQIYQNGISTRA--STLKILGNPLLGIYMFRHV
DIALNYSHSRSIPVESILIFKV-LFGKVK------KIQPSVDKNKVSLDPSPNFDCHMSR
NAPSLKDTIE-LQAYSSAVYFYEYSVLSKPVDKPRQCL

ENSGT00390000006260_0_Linker_0_1 (279, 2115)

PYAVVTVKFLGSKVDNGYLMTS
LRFLATGFPKRAERTCSLNNCTVAKRIGKGKDATVIFEHFKKPVDPF---VQENCLCNVL
NSEINPSNSHISNSYGNVQNG-NISVPETYNGQTEHNLAEIRDTSQVLAHDSDLSLMPSD
AKGSV-NGDLLLNWTSLKNILSSLNAAFPLHNSTGSSTVTTSKFIKDPRLMRREESMGEQ
SNTAGLNEILQFEKSLDNVNSEIK---STPSNSASSSEVVPGDCAVLTNCLDAPCFKTCV
NDSQSWAHNTGSEDYNSVPHNKVTMAGQCKDQ---G-NFSFPISVSNVVSEVENQNHSEE
KVQRAQQ---------------------------ESD---NVYKKEYNSRISQELQSSDL
KTIYQTGHQMS-TIFPLKKKVS-IDEYLQNTGKMKNF-TDLKDNS--KHEEKQTSWKEID
N-DFTNETKISPMDNYIVLHQE--YKESESHNSFEKSCDKILITQEL-EIPK-SSTSTVK
DKDELDHLALEWQ--IT-PSLESLSQKHPQHSVEYED-NIHTSLAISQKLMELKLGKIN-
ANCASIITEAFPKPKDIPQAEEILTDTVISSYNIETAHDNSNCSITREHICVHRKNENEP
VSSENIQRDYKETAYVE---DKGQDHSLFCNSQL-NNIC---LNVNFK-EQRGNYKE---
---NQNEAKE-N-NASSVENNIENIYGDKKQDSHTN--KNFSY-IDEKED-KNYNNIEIL
SSEEFSATFNLICREK-YVSAATALLES--EEDTISAMKQKDTE-NTGRSVEHLASTA-F
PEI---ASSSVCVASNAAVQIASATMPVLS-ISNDEHQIYQSKETCSSESPDFGLLVKHR
VSDCEIDKDKNKSQESFHQSIN-EN---LVLQSIELESEI--EIEDCDDAFI--FQQDTH
SHENMLCEEFVTSYKALKSRISWEGILALDNGQMEVLESTAGRENSDQHYSKESSYFYSS
TQNGETELPSPILLPDLQIRIT-NIFRPGFSPTVDSFALKDNFCTHVTEATKPEINKE--
----DGEIVGFDIYSQPSGENSDYPCEDKVDNI-RQESGPMSKS-EISLSFDLS-DNTDV
---NHMSK-NQNSESLFSEPSNVT-IIDNGSRCFFTNSK-TDYNDTKEKKEAESRISKRK
L-HTSSRDQNI-HKDLRQHKIYGRKRRLTSQDSSECFFSLSQGRIKTFSQSEEHIKSVLN
ILSGEASLCKSKCLSKKLDKAVIHLKKAHRRVHTSLQLITKVGEK-RKGPLPKSYAIICN
NF-WESCDLQGYSSVSQRKYCSTKHFWSKRRYDKRRKKRVPKADISKSLTYVSKHKSYK-
T------SGE--KKCLSRKSMASSVSKSHPT-IHVGEFCNQE-HPGSQLSVSSTSQSTSQ
S-VYYNSSVSNPSLSEEHQPFSGK-TGCLFSPDHSDEKLIEKENQIDTKFLSSTSKYEKL
EKHSANHNVK---DATKENSCEANQVINESNSISLSCIKE-NINYNTGN-DYDATCIGCT
KVKTDVLISVLDSNVKHFLN-DLYQQENLILSDYKRNLEVKW-----TAPIERSKQSIIT
GNFLMDPLNLTLIASKK-YSIPQL-SASAVTDSEGESSKSYLDKQRILTIDSFAAST---
---TIPCCEQSCRGK--ELLKTEQCSSGNCLHTDGNETNVT-ENYELDVAS-VTEESRS-
-YGENI-------M-KLSSSDSSLLLKDNIKGSSSETCIVKKDTEDRITWKVKQVEKA-K
DSV----YKSSMTE-GSTVNTEYKNQKNQIS-EES-CLNEKIIKTNLIDSHLS-TKNTTT
E-SVSLKNTVSNPL

PF15326 // ENSGT00390000006260_0_Domain_1 (2115, 2382)

NKRE-K-AEIKV-SNDSQS---------------------------
-DLTLYSEIAYISK---PGILGVNHTPILPAHSETCKVTTLL-KKPASYMSEFKEKHCSA
NHTALIANLSQILQRADEASSLQILQEETKVCLNILPLFVEAFERKQECSVEQILISREL
LVDQNVWNNCKHTLKPSAVDTLVELQMMMETIQFIENKKRRLEGEPTFRSLLWYDETLYA
ELLGKPRGFQQQSNFYPGFQGRLKYNAFCELQTYRDQLVEL

ENSGT00390000006260_0_Linker_1_2 (2382, 2603)

LEETKREKNSYYAFLKYKR
QVNECEAIMEHCSDCFDFSLSVPFTCGVNFGDSLEDLEILRKSTLKLISACG-DSPKVHS
YPGKQDHLWIIIEMISSKINFIKNNKAVHIKISLYGLEHIFFDAAKNLVWKEETQSFSKK
YSQKEDKERLLRVNTCAFSKLQKIYDTLSKDLNNEP-ISPVGLEEDTIIASRKSDHPINK
ATISIENSKFGS---SLLAHPD

PF15326 // ENSGT00390000006260_0_Domain_2 (2603, 2722)

IYCIGEILDQAEVADLKKLQDLTLRCTDHLEILKKYFQ
MLQDDNMDNIFITEENVLDMVKNHSYEARLLKPEAIEMYIEIVMVSETIHFLKNSIAKKL
DKQRFRGMLWFDLSLIPELVQCQEKMTSFSFLKDNSTDVCLWKVIETAIFELKKDLDVIY
KYDE-AVNRSYAIHLLSRELQELSEIKKLLKNSKYFISTYIDFVPYITSINYGSTLMELE
YNYNQFSTLLKNVMSAPRKDLGKMAHIMKVMKTIEHMKIICAKNAELTISFFLCQMLYNG
RKILQ-LKRKEKMNIHVVKPGENNNKFSISM-MVPPISECINKNISNSSKKRPSTVDTCE
D-SQEQQKNTTVSSCKKLKVDMKDVTKISRENATFKHPRTTGSHPQSENKIVSSSSNNLK
RNHL-TSKKVEMQRSLPGSLSPLENPKDTCTSKSERKIDLT-VSSDAPDHFTGQQENL-N
SMRK--RNVNFSAAETKSDEKDCAAFAICDQKSAHG-TFLPDREILLQKFLKNSPDPTQK
SCLSDINPGTDVSLVPDA-SVLSKPIFCFVKDTHTDLEMN-DTVFKLQDNDIVNSSIKNS
S---CVTSPEPICIQNKIPTLQINELQPAETESEDKYMKNTLNPNTVHTFGASGHITLNV
NQGAEYSLSEQQ--NDKNSKLLTQNAATYWNELPQSACTPTYNSSEHLFG-TSYPYSAWC
VYHYSS--S-----TQTYQGITSYELQS---PPSGLLTTVASGQGAQRAQGAHSNLLYSQ
YFTYFAGEPQANGFVPVNGYFQSQIPA-YNFQQPVFSQYASHQPLPQTTYPYLPNRDVPP
EVPWVYAPWH-QESFHPQH--

--------LATNKMEMKKVAKHKTLWKMSST----SEPLLITGVEVNPLKKFTIPKIRRT
AGKVYLSPCSTNTREYGFIHDTLNQCRLDVSCDLQS-SWQFGDTKLVHNEELEKNFSAKR
S

PF12509 // ENSGT00390000006260_0_Domain_0 (122, 279)

EMRESGRHGRELEEHFCFLALPRRDVTEICQNGISTKA--STLKILGNPLLGIYIFRHV
DVALNYAHSQSITVESIIIFKV-LFGKVK------KIQPSVDKKKVSLDPSPKFDCHMSR
SIPSLKDAIE-LQAYSSAVYFYEYNVLSKPVDKPRQCL

ENSGT00390000006260_0_Linker_0_1 (279, 2114)

PYAILTVKFIGQKVDNGQLVTS
LKFLSTGLPKRTERACSLNNCTVAKRIGKGKDATVIFEHFRKPVDPF---VQENCSCSAL
NSEINSSNSNISNSCGNVQNG-TISILETYHGQTEHNLAEIRDTSQVHAHDSGPSFISSD
TKENV-NGDHLSNLTYLKNILSGLSAAFPLQNNIGSSTVITSKLIKDPRLMRREESMGKQ
NDTASLNEILPFEKSLGYVNSEIN-LSSMPVSSAS-SEVITRDCSLLTNCSNAPAFKISF
DDSQSQAPTLGSKDCDFTTPNNITMTGQCKNQ---E-NFSFPVSLSNVISEVENQKHNGK
EAQR-------------------------------SM---NTCTKEYSSHISQESQSSDL
KTIYHTDHQMS-TVFPFQKKES-INEYIQNIGKMRNF-TDPQDNF--KHGEKQTLWKEID
--YFTDETKIHPIDNYVSLCQE--YKDSESLDSLGKNCDKILITQEL-EIQK-SSTPATK
DKDKLQHLALELQS-IT-PGVESLSQKHLQYSLEYED-NTHTNFAIAQKLMELKLEKTT-
QNCASIVTDAFQEVKDIPQAKEMLIDTVTSSHDIETAHENSNCNITREHVCVHRKNENEP
LSLENIQRDCKETHH-----TEGQDHTVFFNAQLNNDTC---PNVNFR-EQGDNDKD---
---NQNEAKETD-SASSPENNIESIHGDEKQSFHTN--KNFIN-INERRENKNYNNVEIL
SSEEFSATVNLIWGGR-YVPTETALLES---EDTINAAKQNDTQ-NTGRSVEHLAATT-I
PEI---SSSSECVSSNASVQIASTAMPTLS-TDHEDPHRYQFKETCSSESTGFGLLVKHR
VSDCEIDTDKNKLQDSFHRSKS-EN---SVLQNFKLENEIEVGSEQCDDACL--FQQDAH
SHENVLYEDSEALYEDLRSRIDWEGLLGSNNGETEILKSSTRRENNDQHYSKESNCFHSS
TQKNKTELLNPILLPDLQIRIT-NIFRPGFSPTADSLVLKDNFWTCITEATKPETNKE--
----GEEALGFEIYSQPSGKNSDYPGEDKVGNI-LQASGLVSKS-EISVSFDLS-ENTHV
---NHMSE-RQNSESLFTEPS-TA-TINDGSRCSFTKSK-LDCNDTRSKKEVELRTSKRK
L-HTSSRDQSISPKDLRPHEICEKKRRLTSSDPSECFSSLSQGRIKTFSQSEKHIRSVLD
ILNSEASLCKSKRLSRKLDRAVVHLKKAHRRVHTSLQIIAKVGEK-SKGPLPKSYAIICN
NF-WESCDLQGYSSVSERRYYSTKHFLSKRKYDKQGEKRVLGFDVDKSLTHGSKHKSYK-
L------SGEKITNCLSKKSVASSVSRSHTT-IDVREFCDKEQHPESQLSLSSISQSTNQ
P-VYSNNSMRD-PGLSELQPFSAK-TGHLSPSDHSDEKLTEKDNQSDAKSLSNISKYEKL
ESRSAHDNTK---DATKEHNCETSEVMNESNSVSLSCIKENNVSYSTDK-NYDATCIAHT
KVKTDILISVLESNVEHFLNVDMCKEDSLILSGCKRNLKVNFPS---------FERSIIT
GSFLMDPLNLNLIASKK-YSIPQLFSTTSVTDSEGESLKSYLGKQRIFAIDS---S----
---SASHYQQICSRK--EILKTEQCSSSNCFHIDGNETVVT-EKSELDLTS-ATEENKG-
YYGKNT-------MKKLSSNDSSLLLNGNIKGSS-SKCIVKKDIQDRKMCKVKQAEKA-K
DSV----YKRSMTE-GSTVKAEYKSQKNEILKEDSSHLNEETIKNNLIDSHVS-TKNTTK
A--VSLNNIVFNQ

PF15326 // ENSGT00390000006260_0_Domain_1 (2114, 2382)

LNKRE-KKGEIKI-SNDSQS---------------------------
-DAMLHAETAYISK---PDILGVNYMPILHAHSETSKVTAHQ-KKATSCLNELNEKHCST
NHTALITKLSQILQRADEASSLQVLQEETKVCQNILPLFVKAFERKQECSFEQIVISREL
LVEQNLWSNCKCKLKPCAVDTLVELQMMMETIQFIENKKRLLGGEPTFRSLLWYDETLYG
ELLGRPRGYQQQSNFYPAFQGRLKYNAFCELQTYHGQLIEL

ENSGT00390000006260_0_Linker_1_2 (2382, 2576)

FEETKRGDNSYYAFLKYKR
QINECEAIMKHCSDCFDFSLSVPFTCGVNLGDSLGDLETLRKSTLKLISIYG-DSPKVHS
YPGKQDHLWVIIEMISSKVNFIKNNEALSIKISLYGLEHIFFDAAKSLVWKEKRRSFSKK
YSRKN-KDMLLKMNQCAFSKLKKIYDTLSKDLNNEP-ISNNGLEKNATVASRKSD

PF15326 // ENSGT00390000006260_0_Domain_2 (2576, 2724)

DL-NK
ATISIENYRFNG---TLLSHPDICGISEILDQAEFADLKKLQELTLRCTDHLEILKKHFQ
MLQEDNIDNIFITEENVLDMMKTHNHGAVILKPEAIETYVEIVMVSETVHFLKNSMAKKL
DKQRFRGMLWFDLSLLPELVHGQEKMASFSFLKDNSTDVCLWKVIETAISELQKDVDIIY
KYSE-AVNCSYALRLFSRELEELSEIKKLLKKSKYSISTYIDFVPYIASINYGSTVTELE
YNYSQFSTLLKNTMSAPRKDLGKVAHIMKVMKTIEHMKIICAKNPKLAISFILCQMLCNR
RKTFQ-PKRKEKMNVHVIKPGGNISKSSMSM-KMPLIPEHIIKNVSNSSEKRPIAIDKCE
D-SEEQEKSTDISSCKKQKVNMKEVTKI-REKTTCKHPRTTESPPKSENKIESSSSDNLK
RNR-ISPEKTEKQRLLPGSLLPLKDLKGTCSLKAESRIDLSNIASDASQHFTGQQGNL-N
SLKK--KNKNFCAAETKNDTKDCVAFALCDQKSIDG-TFSKDRETFPQKFLESSPDSTQQ
TCLLDIKPGADASLVPNA-SVLSKPVFHFVKDVHTNLEMN-DTVLELQDNEVLNSSIKNS
T---CMNSPVPIFIQKKIPVLEISKTQSAKSESEEKYTKDTLNPSTV-SFEASGHITLNV
NQTAEYSFSEQQ--NDENSKVLTQNGATCWDELPQSVCTPIYNSSEHSFG-TSYPSYAWC
VYHYSSS-SSGNAITQTYQGITSYEVQA---PPSGILTAVAS-----TVQSTHSNLLYSQ
CFSYFAGEPQAHGFVPVSGYFQSQMPISYSFQQPIFSQYASHQPL-QAPYPSLPNPAVLP
EVYWNSTPWQ-QEPFQPGR--

-----MTTSATNKMEMKEISKQKTLRKMSST----REPFPNTGIEVSSLKKFTIPKIRKT
SGKVYLSPCCTNTREYNFICETLNQCRLDVSCDLQS-SWQFGDTKLVHNEELEKNFTTKR
S

PF12509 // ENSGT00390000006260_0_Domain_0 (122, 279)

EMRESGRHGRELEEHFCFLALPQRDVVEIYQKGLSTKA--STLKILGNPLLGIYIFRHV
DVALNYAHSRSITVDSIIIFKV-LFGKVK------KIHPSVDINKVSLDPAPNFDCHMSR
SIPSLKDTIE-LQAYNSLVYFYEYSALSKPVDKPRQCLPYAIITVKFIGHEMDNGYRKTS
VRLLTTGFPKRSERNCCLNNCTVAKRIGKGKDATVIFEHFGKPVDPF---ALENCSCSTQ
NSAINSFNANISDSYENVQNG-NMSILETYGGQSENSLAEIRGTSQGLACDSNRSFMPSD
NKGSGNSDD--MFSTYLKDILNVMSPTFPSHNNIGSSTLITSKFIKDPRLMKKGESLGKQ
NNIIGFSEILPFEKNLDH-NSDIN-LSCVATNSTSSSEVVPSDCAILSDCLDT--NKFSF
DDSPSQTQNMDPVDY-CVAP----WVRQYKDQ---G-NFPFPISLLNV-SELENQKHSKA
TAQRAQEKNNIPLLMKHSSRPHS---------SYESV---NTDRKDSSSRNSKELHSSNF
STLYHTGHQIS-TVFSAQREGN-MHECIQNTSKIRNF-TDPEDSY--RYEEKQTLQKETD
N-YFTNETKITPISNYISSCQE--YKDDETLDPLGGNMDEIAVTQEL-EMPE-SPIFTTK
-DNEQDQLALDLESNLT---LESISQKHPQHSTDYGG-SMPMSFGFTQKLREMNLEKTN-
KNYVSIITDTFQEAEEVLQTRELLANSM--FHGIEIALNNSKCSKTTEYLYVQKKNENEP
VLLENIQRDCKENPYFE---DEYQPHMLSGTAQLNYDKF---LNTHFK-GPRDNDKE---
---NKTEAEED----------DRTICGNEKEECHTN--NTLTS-IEDRKKNKNDNKFEIL
SSEDISTAFNFIWKEK-DKSPKTTL-DN---EDTFAAMKQRDVQ-NTRRNVEHLALTP-F
PEV---EGLSVGIASNPTIELANTALPTSS-TNHEAHQRYQFKETHSSKSPDFGLLVKHK
IADCGIDVDKNKLQDSLHQPVN-EN---SVLQNFDVESEIEVELEEYDDDFL--LQQNRH
SHEDTLDEE----YEALKSRIDWEGLFGSSNGKMNDLGST-IRENIDQHHSKNTITFCSS
Y--K---KLYPILLPDLQVRIT-NTIRQTFIPPEDTLLTKENFSECLTEASKPERNEEE-
---KAMKAPGFEVDSKSVCENLGCPCEDQFDNS-MQDSGLVSKS-EISHSFNLS-HNTD-
---NHMSE-KKNSESFCSEPSNVT-TINNEHKCFFKKSK-TNFNT---------------
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---------MANKMEMKETAKQDTLWQMSST----SKPVLNTC-EVNPLKKFTIPKIRRT
AEKVYLSPCYTNSREYSFIHDTLNQCRLDVSCDLQS-LWQFGDTKLVHNEELEKNFTAKR
S

PF12509 // ENSGT00390000006260_0_Domain_0 (122, 279)

EMRESGRHCRELEEQFCFLALPQSDVAQIYQNGISTRA--STLKILGNPLLGIYMFRHV
DIALNYSHSQSITVESILIFKV-LFGKVK------KIQPSVDKNKVSLDPSPNFDCHMSR
NAPSLKDTIE-LQAYSSAVYFYEYSVLSKPVDKPRQCL

ENSGT00390000006260_0_Linker_0_1 (279, 2115)

PYAVVTVKFLGSKVDNGRLMTS
LRFLSTGFPKRAERTCSLNNCTVAKRIGKGKDATVTFVRFKKPVDPF---VQENCLCNAL
NSEINPFISNISNSYGNVQNG-NISIPETYSGQTEHNLAEIRDTSQVLAHDSDISLMPSD
AKDSV-NGDLLLNWTSLKNILSGLNASFPLHNNTGSSTVTTSKSIKDPRLMRREESMGEQ
SSTAGLNEILQFEKSSDNVNSEIK---STPSNSASSSEVVPGDRAVLTNGLDTPCFKNSV
NDSQSWAHNMGSEDYDCIPPNKVTMAGQCKDQ---G-NFSFPISVSNVVSEVENQNHSEE
KAQRAQQ---------------------------ESG---NAYTKEYSSHIFQDSQSSDL
KTIYQTGCQTS-TVFPLKKKVS-IDEYLQNTGKMKNF-ADLEDSS--KHEEKQTSWKEID
N-DFTNETKISPID--IVLHQE--YKERESHNSFGKSCDKILITQEL-EITK-SSTSTIK
DKDELDHLALEWQ--IT-PSFESLSQKHPQHSVEYEG-NIHTSLAIAQKLMELKLGKIN-
QNYASIITEAFPKPKDIPQAKEMFIDTVISSYNIETAHDSSNCSITREHICVHRKNENEP
VSLENIQRDYKETAYVE---DRGQDHNLFCNSQLSNDIC---LNVNFK-KQTD--KE---
---NQNEAKE-N-SASCVENNTENIYGDKKQDSHTN--ENFSN-IDEKED-KNYHNIEIL
SSEEVSTTFNLICRENNAVSAATALLES--EEDTISAVKQKDTE-NTGRSVEHLASTT-F
PKT---ASSSVCVASNAAIQIASATLPALS-LNNDDHQIYQFKETCSSESPDFGLLVKHR
VSDCEIDTDKNKSQESFHQSIN-EN---LVLQSIELESEIEIELEDCDDAFI--FQQDTH
SHENMLCEEFVTSYKALKSRISWEGLLALDNGEMEVLESTTGRENSDQHYSKESNYLYSS
TQNNETELTSPILLPDLQIKIT-NIFRPGFSPTADSLALKDSFCTHVTEATKPEINKE--
----DGEILGFDIYSQPFGENAEYPCEDKVDNI-RQESGPVSNS-EICLSFDLS-RNTDV
---NHTSE-NQNSESLFTEPSNVT-TIDDGSRCFFTKSK-PDYNDTKNKKEVESRISKRK
L-HTSSRDQNIPHKDLRRHKIYGRKRRLTSQDSSECFSSLSQGRIKTFSQSEKQIKSVLN
ILSDEASLCKSKCLSRKLDKAVVHLKKAHRRVHTSLQLITKVGEE-RKGPLPKSYAIICN
NF-WESCDLQGYSSVSQRKYYSTKHFLSKRKYDKRRKNRAPKADISKSLTHVSKHKSYK-
T------SGE--KKCLSRKSIASSVSKSHPT-SHMGEFCNQE-HPESQLPVSSTSQSTSQ
S-VYYNSSVSNPSLSEEHQPFSGK-TGYLFSPDHSDEKLIEKENQIDTEFLSSTSKYEKL
EKHSANHNVK---DATKENSCEANEVINESNSVSLSCIKE-NINSSTGN-DCDATCIGHT
KAKTDVLISVLDSNVKHFLN-DLYQQGNLILSDCKRNLEVKW-----TDPIERPKQSIIT
GNFLMGPLNLTLIASKK-YSIPQL-SAAAVTDSEGESSKSYLDKQRILTVDSFAASS---
---TVPHCEQSCREK--ELLKTEQCSSGNCLHTDGNETNVT-ENYELDVAS-GTEENKS-
-YGENI-------V-ELSSSDSSLLLKDNVKGSSSETCIVKKDTEDRITWKVKQVEKA-K
DSV----YKRSKTE-GSTVNTEYKNQKNQIS-EES-CLNEKIITTNLIDSHLS-AKNTTT
E-SVPLKNTVSNPL

PF15326 // ENSGT00390000006260_0_Domain_1 (2115, 2382)

NKRE-KKGEIKV-SKDSQS---------------------------
-DLTLHSEIAYISK---PGILGVNHTPILPAHSETCKVPTVL-KKPASYVSEFKEKHCSA
NHTALIANLSQILQRADEASSLQILQEETKVCLNILPLFVEAFERKQECSVEQILISREL
LVDQNLWNNCKHTLKPCAVDTLVELQMMMETIQFIENKKRHLEGEPTFRSLLWYDETLYA
ELLGKPRGFQQQSNFYPGFQGRLKYNAFCELQTYHDQLVEL

ENSGT00390000006260_0_Linker_1_2 (2382, 2544)

LEETKREKNSYYVFLKYKR
QVNECEAIMEHCSDCFDFSLSVPFTCGVNFGDSLEDLEILRKSTLKLISVCG-DSPKVHS
YPGKQDHLWIIIEMISSKVNFIKNNEAVRVKISLYGLEHIFFDAAKNLVWKERTQSFNKK
YSQKKDEERLLRVNKCAFSKLQK

PF15326 // ENSGT00390000006260_0_Domain_2 (2544, 2722)

IYDTLSKDLNNEP-ISPIALEEDTIIASRKSDHPINE
ATISIENSKFNS---NLLAHPDICCISEILDQAEFADLKKLQDLTLRCTDHLEILKKYFQ
MLQDNNMDNIFITEENVLDMVINHSHEAIILKPEAIEMYIEIVMVSETIHFLKNSIAKKL
DKQRFRSMLWFDLSLLPELVQCQEKMASFSFLKDNSTDVCLWKVIETAISELKKDLDIIC
KYNE-AVNCSYAIHLLSRELQEFSEIKKLLKKSKYFISTYIDFVPYIASINYGSTVTELE
YNYNQFSTLLKNVMSAPRKDLGKMAHIRKVMKTIEHMKIICTKNAELTISFFLCQMLYNR
RKILQ-LKRKEKMNIHIVKPGENNNKFSIST-MLPPVSECINKNISNSSKKRPSTVDKCE
D-SQEQQQDTTISSCKKLKVDMKDVTKINREKATFKHPRTTGSHPKSENKIVPSSCDSLK
RNHL-TPKKVEMQRSLPGSLLSLENPKDTCASKSESKIDLT-VSSDAPDHFSGQQENL-N
SMKK--RNVNFSAAETKSDKKDCAAFAICDQKSVHG-TFSPDHETLLQKFLKNSPDPTQK
SCLSDINPETDVSLVPDA-SVLSKPIFCFVKDVHPDLEMN-DTVFELQDNDIVNSSIKNS
S---CMTSPEPICIQNKIPTLQINKLQPAETESEDKYMKDTLNPNTVHTFGASGHITLNV
NQGAEYSLSEQQ--NDENSKVLTQNAATYWNELPQSACNPTYNSSEHLFG-TSYPYSAWC
VYHYSS--SNGNAITQTYQGITSYEVQP---SPSGLLTTVAS-----TAQGTHSNLLYSQ
YFTYFAGEPQANGFVPVNGYFQSQIPA-SNFRQPIFSQYASHQPLPQATYPYLPNRFVPP
EVPWVYAPWH-QESFHPGH--

MRDWCSPSTASNKMEMKEITKPKALWKMSSP----SEPSLFTGVEVSALKKFTIPKIRKT
AEKVYLSPCCTNTREYSFIHDTLNQCRLDVSCDLQL-SWQFGDTKL

PF12509 // ENSGT00390000006260_0_Domain_0 (107, 279)

VHNEDLEKKFTAKR
SEMRENGRHGRELEEHFCFLALPQSDVAEIYQKGISTKS--STLKILGNPLLGIYIFRHV
DIALNYAHSHSITVENIIIFKV-LFGKVK------KIQPSVDKNKVALDPSPNFDCHMSR
SVPSLKDTIE-LQAYSSMVYFYEYSILSKPVDRPRQCLPYAIVTVKFIGQRVDNGHLMTS
LRFLSTGLPKRAERPCSLNNCTVAKRIGKGKDATVIFEHFRKPTDPF---VQENCSCNSL
NSEKNLSNSDISNSYGNIQNG-NISTLETYSGQADHDLTEIRGTAQANGHDSNLSCMPND
NRESV-DGDLLLNLTYLKSILSSLSTAFPLHNNPESSTVITSKLIKDPRLTKREESLGKQ
KNTASFNEIVPFEKSLDCINSEIN-LSSVPTNSTISSEVVPGDPAVLANCVDAPCFRFSV
DETQSQVHHMDYRDNHCITPSKVTMTEQWKDQ---G-NVSFPISLSNVVSDNETQKHSEE
KSQRAQQRSSSPFLIKHRSEPYD---------SYKSA---NTYTEENSSQVPQELQSSNL
KTVDHIGHQIS-TVFPLHKKES-IDEYIQSLGKMRNF-TEPEENS--RHGENHTFWKEI-
N-YFTNETKVSPVDNCISLNQE--YEENDILDSFQKNYDKILISQEL-EIPK-SFTSTTK
DPSELDHPTMELQNNLT-PSIESLSQN--QHSLEYDD-SIHTNFPIAQKLMELNLEKAD-
QNCVNILTDGLQEAENIPQDKEVLVGKVISSCAIETAYDNSNCSVSGEYTCVHENNENEP
MSLENIQRDNKQTLNVE---DECQYHTVFCNAQLNNETY---LSINYR-EQRDSDKE---
---NKNEDKKEY-SASSSENSIENICVDK-KDFHTN--INLTS-IDEERNNKNYNKVETP
CSEGFSSTVNLIWGAK-YESTEAALLES-----KDTDIKQKDTL-NTGRSVEHLDAIT-L
SEI---PGSSVCVTSNTTGQVADATLPVLN--TSHDHQIYQPKKSYSSENPDFG------
VSDSEIDIDKNKLQDSFHHAKN-EN---LVLQSVELENEIELGSEQDDDAFL--FQQDTH
SHESVLDEEFEASYEALKCRIDWEGLLGSSNGETGAMESTARREDSDQHCCKESNSICFP
SQKNTTEMLNPILLPDLQVTVT-NIFRLEFSPTFDYVRLKDNFYKSTTDSTKQEINKK--
-----GETPGFEIFSQLSGENSAFPCEDKSGNI-RQESGPGSKS-EVSLCSDLS-QNPQV
---NLTSE-RQNRDSSFTKPSDVT-IVNDESS--FKKSK-TDHNET-NKKDMESRTSKRK
L-RTSFRSQNIPHNDFRQHEICRKKRRLSNQDSSECFSSLSQGRIKTFSLTEKHIRNVLD
ILNNEASLCKSKRLSRKLDRAVLHLKKAHRRVHTSLQLIAKVGEK-RKGPLPKAYAIICN
SF-WESCDLQGYSPVSERRYYSTKHFLPKRKYDKQGEKKASEFDVAKSLTSVSKHNSYK-
T------NGERIKKCLSKKSMISNISRSQAT-VHVTEFCHQE-HRKSQVSVSSASRSTSQ
S-IYINSCMSN-PLSSELQPFSGK-TEYLFPPDHPVEELTEKENHSDRKLLSNISKYENL
ENCSPPNND------ATKETSEASKEINDYNSISSSCMKENNINYSIDK-N-DEACLAHK
KVKTDILISVLESNVMNFLN-YIHKRGKLILSGCKMNLEVNFPIKQCPAPFESSRANNIT
GNFHMDPLKLTLIANKK-HSIPQLLSATPVMENEEEYSKSNLDEQGIFAVDSCVTSM---
---TASNCQQICDGK--ELLKTKQCSLSNCFPIDGNETNVT-ENSELDLTS-ATEESKN-
-YRKNI-------MKKPSSNADLLILKDNREGS-SRKCIAKRRIKDRKKCEAEQTEKA-K
NSR----YKKRRTE-TTAIRTAYKNPRNNIL-E-DSRLNDKITENNLIDSHVS-IKNTVE
T--VCLNSTVSNQLKKRKEKEGEIRS-SNHPQS---------------------------
-D--------YISQ---PSILEINHMPVSLAHSETSEVITLP-TKPTLYTSDLIENHYSV
GHMALLVELSQILQRADEATSLQLLQEESMVCQNMLPLFVQAFEKKQECSLEQILITREV
LVEQNLWDNCKHKLKPCAVDTLVELQMIMETIQFIENKRRLLEGEVTFRSLLWYDDTLYG
ELLGRPRGYQQQSSFYPGFQGRLKYNAFCEMQNYHNQLIELCDDMKRKNNSYYAFLKYKR
QISECKAVLKNCSDCFDFSLSVPFTCGVNFGDTLGDLENVRKSTLKLISLCE-NSTKTHL
CPGKQDHLWIIIEMISSKVNFIKSNEAVSIKIALFGLEHIFFDAAKNLVWKEKRQSFSKE
YSQK-NKEMLLKMNQCAFSKFQEICDTLSEDLNSEQ-ISSMQLEEATVMASRKSEEPINK
AIISIENCRFNN---TSLSHLNISCVGEILDQAEFADFEKLQDITMRCTEHLETLKKYFQ
VIQE-NMDNIFITEENVLDVLKNHKQRAVILKPAAIETYIEILMLSETVHFLKNSIAKKL
DKQRFRGMLWFDLSLLPELVHCQENMASFSFLKDNSAD-CLWKVIETAISEVKKDLDIIC
KYSA-AVNCSYAFHLFSREFKELTEIKNLVEKSEYSISTYIDFVPYIASINYGNTVTELE
QNYSQFSALLKNVMAAPQKDLGKMAHIMKVMKTIEHLKIICVKNAKLAISFILCQVLSNR
RSTSK-LNIKGNIDTQVRKPRKNNSMSSISM-K-RSVSEYITKSVSNTSKKQPVTADNCE
D-SQEKEKNTTVSSCKKQKVNMKDETKINRKKIAVKHPRIAGYHPQNENQVRLHLSDNRR
RKPV-SPEKVEMQRSPLGSVSPLKNLKESCTTKAESKVDSINISLDTSEHLSGQQGSL-N
RIKK--RHVNFTATETKSDMKDCAAFVICEQKSADG-TFLKDLETPPQIFLKDSPDLTQK
SSLSNIKPGNNDSLGHHA-SVLSKTVLHF--DIHSNLEVN-DTIVEFQDNEILNSSIKNS
T---CTSSPEPVCIQDKIPVLEINKIEPGKPELEGKCLKDTLNPSSV-PFGESGDIKLNV
NQRAECSFFDPQ--TDENSKVLAQNAASDWNGLPQLPYTPLGNSSEHSFG-TSYPYYAWC
VYHYSS--SSGNAITQTYQGITSYQVQP----PPGMITAVAS-----TVQNTNSNHLYSQ
SFSYFSGERQANGWVPVNGYFQSPMPVSYNFQQPTFSQYASHQPLPQTTYPYPPNTGVLP
EVPWVFAPWQ-QEPFHPGC--

-------------MEMKETAKQNTLWQMSST----SEPMLNTR-EVNPLKKFTIPKIRRT
AEKVYLSPCYTNSREYSFIHDTLNQCRLDVSCDLQS-LWQFGDTKLVHNEELEKNFTTKR
S

PF12509 // ENSGT00390000006260_0_Domain_0 (122, 279)

EMRESGRHCRELEEHFCFLALPQSDVAQIYQNGISTRA--STLKILGNPLLGIYMFRHV
DIALNYSHSRSIPVESILIFKV-LFGKVK------KIQPSVDKNKVSLDPSPNFDCHMSR
NAPSLKDTIE-LQAYSSAVYFYEYSVLSKPVDKPRQCL

ENSGT00390000006260_0_Linker_0_1 (279, 2115)

PYAVVTVKFLGSKVDNGYLMTS
LRFLSTGFPKRAERTCSLNNCTVAKRIGKGKDATVIFEHFKKPVDPF---VQENCLCNVL
NSEINPSNSHISNSYGNVQNG-NISVPETYNGQTEHNLAEIRDTSQVLAHDSDLSLMPSD
AKGSV-NGDLLLNWTSLKNILSSLNAAFPLHNSTGSSTVTTSKFIKDPRLMRREESMGEQ
SNTAGLNEILQFEKSLDNVNSEIK---STPSNSASSSEVVPGDCAVLTNCLDAPCFKTCV
NDSQSWAHNTGSEDYNSVPHNKVTMAGQCKDQ---G-NFSFPISVSNVVSEVENQNHSEE
KVQRAQQ---------------------------ESD---NVYKKEYNSRISQELQSSDL
KTIYQTGHQI-------------IDEYLQNTGKMKNF-TDLKDNS--KHEEKQTSWKEID
N-DFTNETKISPMDNYIVLHQE--YKESESHNSFEKSCDKILITQEL-EIPK-SSTSTVK
DKDELDHLALEWQ--IT-PSLESLSQKHPQHSVEYED-NIHTSLAISQKLMELKLGKIN-
ANCASIITEAFPKPKDIPQAEEILTDTVISSYNIETAHDNSNCSITREHICVHRKNENEP
VSSENIQRDYKETAYVE---DKGQDHSLFCNSQL-NNIC---LNVNFK-EQRGNYKE---
---SQNEAKE-N-NASSVENNIENIYGDK------------NY-IDEKED-KNYNNIEIL
SSEEFSATFNLICREK-YVSAATALLES--EEDTISAMKQKDTE-NTGRSVEHLASTA-F
PEI---ASSSVCVASNAAVQIASATMPVLS-ISNDEHQIYQSKETCSSESPDFGLLVKHR
VSDCEIDKDKNKSQESFHQSIN-EN---LVLQSIELESEI--EIEDCDDAFI--FQQDTR
SHENMLCEEFVTSYKALKSRISWEGILALDNGEMEVLESTAGRENSDQHYSKESSYFYSS
TQNGETELPSPILLPDLQIRIT-NIFRPGFSPTVDSFALKDNFCTHVTEATKPEINKE--
----DGEIVGFDIYSQPSGENSDYPCEDKVDNI-RQESGPMSKS-EISLSFDLS-DNTDV
---NHMSK-NPNSESLFSEPSNVT-IIDNGSRCFFTNSK-TDYNDTKEKKEAESRISKRK
L-HTSSRDQNI-HKDLRQHKIYGRKRRLTSQDSSECFFSLSQGRIKTFSQSEEHIKSVLN
ILSGEASLCKSKCLSKKLDKAVIHLKKAHRRVHTSLQLITKVGEK-RKGPLPKSYAIICN
NF-WESCDLQGYSSVSQRKYCSTKHFWSKRKYDKRRKKRVPKADISKSLTYVSKHKSYK-
T------SGE--KKCLSRKSMASSVSKSHPT-IHVGEFCNQE-HPGSQLSVSSTSQSTSQ
S-VYYNSSVSNPSLSEEHQPFSGK-TGCLT------------------------SKYEKL
EKHSANHNVK---DATKENSCEANQVINESNSISLSCIKE-NINYNTGN-DYDATCIGCT
KVKTDVLISVLDSNVKHFLN-DLYQQENLILSDYKRNLEVKW-----TAPTERSKQSIIT
GNFLMDPLNLTLIASKK-YSIPQL-SASAVTDSEGESSKSYLDKQRILTIDSFAAST---
---TIPCCEQSCRGK--ELLKTEQCSSGNCLHTDGNETNVT-ENYELDVAS-VTEESRS-
-YGENI-------M-KLSSSDSSLLLKDNIKGSSSETCIVKKDTEDRITWKVKQVEKA-K
DSV----YKSSMTE-GSTVNTEYKNQKNQIS-EES-CLNEKIIKTNLIDSHLS-TKNTTT
E-SVSLKNTVSNPL

PF15326 // ENSGT00390000006260_0_Domain_1 (2115, 2382)

NKRE-K-AEIKV-SNDSQS---------------------------
-DLTLYSEIAYISK---PGILGVNHTPILPAHSETCKVTTLL-KKPASYMSEFKEKHCSA
NHTALIANLSQILQRADEASSLQILQEETKVCLNILPLFVEAFERKQECSVEQILISREL
LVDQNVWNNCKHTLKPSAVDTLVELQMMMETIQFIENKKRRLEGEPTFRSLLWYDETLYA
ELLGKPRGFQQQSNFYPGFQGRLKYNAFCELQTYRDQLVEL

ENSGT00390000006260_0_Linker_1_2 (2382, 2603)

LEETKREKNSYYAFLKYKR
QVNECEAIMEHCSDCFDFSLSVPFTCGVNFGDSLEDLEILRKSTLKLISACG-DSPKVHS
YPGKQDHLWIIIEMISSKINFIKNNKAVHIKISLYGLEHIFFDAAKNLVWKEETQSFSKK
YSQKEDKERLLRVNTCAFSKLQKIYDTLSKDLNNEP-ISPVGLEEDTIIASRKSDHPINK
ATISIENSKFGS---SLLAHPD

PF15326 // ENSGT00390000006260_0_Domain_2 (2603, 2722)

IYCIGEILDQAEVADLKKLQDLTLRCTDHLEILKKYFQ
MLQDDNMDNIFITEENVLDMVKNHSYEARLLKPEAIEMYIEIVMVSETIHFLKNSIAKKL
DKQRFRGMLWFDLSLIPELVQCQEKMTSFSFLKDNSTDVCLWKVIETAIFELKKDLDVIY
KYDE-AVNRSYAIHLLSRELQELSEIKKLLKNSKYFISTYIDFVPYITSINYGSTLMELE
YNYNQFSTLLKNVMSAPRKDLGKMAHIMKVMKTIEHMKIICAKNAELTISFFLCQMLYNG
RKILQ-LKRKEKMNIHVVKPGENNNKFSISM-MVPPISECINKNISNSSKKRPSTVDTCE
D-SQEQQKNTTVSSCKKLKVDMKDVTKISRENATFKHPRTTGSHPQSENKIVSSSSNNLK
RNHL-TSKKVEMQRSLPGSLSPLENPKDTCTSKSERKIDLT-VSSDAPDHFTGQQENL-N
SMRK--RNVNFSAAETKSDEKDCAAFAICDQKSAHG-TFLPDREILLQKFLKNSPDPTQK
SCLSDINPGTDVSLVPDA-SVLSKPIFCFVKDTHTDLEMN-DTVFKLQDNDIVNSSIKNS
S---CVTSPEPICIQNKIPTLQINELQPAETESEDKYMKNTLNPNTVHTFGASGHITLNV
NQGAEYSLSEQQ--NDKNSKLLTQNAATYWNELPQSACTPTYNSSEHLFG-TSYPYSAWC
VYHYSS--SNGNGITQTYQGITSYELQS---PPSGLLTTV----GAQRAQGAHSNLLYSQ
YFTYFAGEPQANGFVPVNGYFQSQIPA-YNFQQPVFSQYASHQPLPQTTYPYLPNRDVPP
EVPWVYAPWH-QESFHPQH--

-------------MEMKEISKHKALWKMSST----KEPLPITGIEASPLKKFTIPKIRRT
AGKVYLSPCCTNTREYSFIHETLNQCRLDVSCDLQS-SWQFGDTKLVHNEELEKNFTTKR
S

PF12509 // ENSGT00390000006260_0_Domain_0 (122, 279)

EMRESGRHGRELEEHFCILALPHKDGIEIYQNGLSTKT--STLKILGNPLLGIYIFRHV
DIALNYAHSRSITVESIIIFKV-LFGKVK------KIQPSMDINKVCLDPSPNFDCHMSR
NVPSLKDTIE-LQAYNSVVYFYEYSVFSTPVDKPRQCL

ENSGT00390000006260_0_Linker_0_1 (279, 2114)

PYAIVTVKFIGQKVDNGHLTTS
SRLLTTGFSKRPERTCSLNNCTVAKRIGKGKDATVIFEHFRKPVDPF---APENCSCNTQ
NSEINSCNANISNSYENVQNG-NISILETFSGKTENSSAETRGISQEHVHDPG-PLMPSD
NKESGNNGC--LFSTYLKDILNLMSASFPPHNNTDSSTVITSKFIKDPRLMKREESMEKQ
NNTVGFSEILPSEKNLDD-NSC------VPTNSASSSEVVPHDCAALSDCLDTPCSRFSF
DDSSSQTHNMDPKDYHCIPPNQITRVRQSKDQ---G-HFSFPVSLLNV-SELENQKHTEE
KAQTAQERSDIPLLIKQNNKAQS---------TYESV---NTYTKDSDSHISKELHSSNF
KTIYQIGHQMS-TVFPLQRKET-IDECIQNIGKIRNF-TDPEDSY--QYEEKQTLQKETD
D-NFTDETKIIPINNYTS-CQE--YKDDETLDSLGENSDEVLITKEL-EMPE-SLASTKE
DKSEQDHLALKLESNLT-LNIECLSQKH-QHSMDYED-STHTSFVFTQKLREMNLEKA--
NKCISIITDPFQEAKDIPQTRE------TSFHGIEIALDNSNCSITREYVCVQRKNENEP
V-SDDIQRNHKETPYIE---DKDQTHILSSNTQLNDDKY---LNTHFK-GQGDNDKE---
---NKNK--END-RTSFPENKIEKIYGRKKQEYHTN--NTFSN-IVDGRKNKNDNKVEIL
ISEDIATTFNLIWGEK-GMSPETSLLED---KDILAAKKQRDVP-NIGRSVEHLALTT-F
PEI---ADSSVGVVSNPMIELANTTLPALS-ANREAHQRYQFKETCSSESPDFELLVKHK
TADCEIDLDKNKLQDSFHQPMN-EN---S-LQNFELGTEIEVELEEYDDAFL--FQQNRH
SHGNVLDEEFEASYEALKSRIDWEGLFGSNNGKMDNLGST-TRENIDHQRSKNTICFCPS
TYKK---EVYPILFPDLQVRIT-NTFTPTFSPPDDTLSVKDNFYKCLTEASTPGINEG--
------EAPGFKIYSKSFCENSGYPCANQFDNS-MQDSGLLSKS-DISHSSDLS-HSTDV
---NDMSG-KK-NDTFSVEPSNIT-TINGDHRCFFTKSK-TDFNDTRNKKKMESRISKKY
I-RASFREQNISHKDLRQREMCEEE-RLTSHDSSECFSSLSQGRMKTFSQSERHIRDVLD
ILNSEASLCKSKRLSRKLNRAVLHLKKAHRRVHTSLQLIAKVGEK-RKGPLPKAYEITCN
NF-WESCDLQGYSSVSERKY--SKHLLSKRKYDKRGE-KVFGFDVNQS-ACVSKHKSYK-
T------NGERIAMCHSKRSVTSSDSKSHST-VCIREFCNQH--SESQLSLFSISQSTSQ
P-EYNN-SIHD-SRSSKLKPFSGK-TEYLLY---SDEKQSEKENQIDMK-LSNISKCEKL
ADHAAHNKDV------AKKNSKVNKIKSKSRSICLSGTKENNVSYSTDK-N-DATYIPHT
QVKTDIFISILDSNMKSFLNVDTYKRDNCIISGCQSNLKVNFPIERWTPSTESYKASIIT
GKFLMGPFSLTLISSKK-YNILQL-STTPVTDSERESSKSCLNKQRILAVDSSATPT---
---TMSHCQQIHGGK--KLLKTQ-SS--SSLHIEGNETSVT-EHSELDLTS-LTRENKS-
-YGENI-------MKR-SFKDSSLLLKDNIKDL-SKKNDAKKDTWNRKIRKNEQAEKA-E
DSL----YQKSMTE-GSIVKIEYKNQKNKTLKEKSPHLNMKTVQSDLIDSHLS-IKTTPE
A--VSLNNTVSSQ

PF15326 // ENSGT00390000006260_0_Domain_1 (2114, 2382)

LNKRK-RKGKRKV-SNDCQS---------------------------
-G--------YISK---PGILEIDHRPILHAHSETSEV-TIQ--KPTSYENELKENHCSV
TQTALVTELSQILQRADEASSLEILEKETKTCQNILPLFVEAFERKQECSLEQILISREL
LVEQNLWKNCKYKLKPCAIDTLVELQMVMETIQFIENKKRLLEGEPTFRSLLWYDETLYS
ELLGRPHGYQLQSSFYPAFQGRLKYNAFCELQNYHNQLIEL

ENSGT00390000006260_0_Linker_1_2 (2382, 2542)

FTETKRENNSYYAFLKYRR
QINECEAIMKHCSDCFDFSLSVPFTCGVNFGDSLGDLEVLRKSTLKLISIYG-DTPTVHS
YPGKQDHLWIIIEVISSKVNFIKNNEAVGIKVSLYGLEHICFDAAKNLVWKEKRQSICKK
YSQK-NKEVIHKMNKCALSKL

PF15326 // ENSGT00390000006260_0_Domain_2 (2542, 2721)

QKIYDTLSENLNKEP-ASNIELKEDTVITSRKSDNLT--
---TVENFRL-S---TLFLQPDICCIGEILDQAEFADLKKLQDLTLVCTDHLETLKKYFQ
MLQEDNIDDIFITEENVLDMLKNHNHGAVILKPEATETYIEISMLSETVHFLKNSMAKKL
DNQRFRGMLWFDLSLLPELVHCQEKMVCFSFLEDNPRD-CLWKAVETGISDCKKDLDVIY
KYSE-AVNCSYALHLFSRELKELSEIKKLLKKSEYPISTYIDFVPYVISINYGNTVTELE
QNYSRFSTLLKNIMSVPQKDLGKIAHIMKVMKTIEHMKIICAKNAKLTTSFILCQILHNK
RNNFQ-LKRKEKMNIHFTIPEENI-RPNTSA-KVPSTSVNLIKNISHSSKRRPNAVDTGE
D-SQEKEKN-TISSCKKRKLNMNYISKINREKAVFRCLRTTGFHPKGENKIGSSSSDNLK
RNYV-SPKRDEMQRSLSASLSPLKNLQGTCTSESESEIDLTNSSSNTSEHHIGQQENL-N
NIKK--RNVNFGAPETKSYKKDCASFATCDLKSING-TLSKDQEIPSQKLLKNLPDPAQK
THLSNLKPATNDSLVPNSSSLFSEPISLSVRDIHTNLEIN-GIVLEHQDNELLDSSINKS
T---GASFPEPIHTHSRYP--------------------DTLSPSPI-PFGASGNLTPDV
NQTAEYSFSQQQ--DEENSKVLTQKAATYWNELPQSACTPVYNSSDHSLQ---TPYYSWC
IYHYSS--SNGNATTHTYQRITSYEGQS---PPSGILTTLTS-----TVQNTHSNLLYSG
YLSYFADQPQANAFVPVNGYFQSQMPISYHFQQPIVSQYASHQPLPQAVYPYPPAPGVLP
EAPWIYAPWQ-QEPFQPRH--

---------ATNKMEMKEIAKYKSLWKMNST----NQPLFVT----NPLKKFTIPKIRRT
AGKVYLSPCYTNTREYSFIHDTLNECRLDVSTDLQS-SWQFGDTKL

PF12509 // ENSGT00390000006260_0_Domain_0 (107, 279)

IHNEGLEKNFTSKR
SEMRETGRHGRELEEHFCFLALRQKDVAEIYHNGISTKA--SSLRILGNPLLGIYIFRHI
DVALNYAHSRSITVESIIMFKV-LFGKVK------KIQPSLDKSKVSLDPSPNFDCHMSR
NTPSLKDTIE-LQAYSSAVYLYEYNILSKPVDKPRQCLPYAIVTVKFIGQKVDNGHFMTS
LRSLSTGFPKRTERTCSLNNCTVAKRIGKGKDATVIFEHFRKPIDPF---VQENCSCTAS
NSEINPSNSDISNCYGNIQNG-NTSVLETYSGHTEYNSAECRDTPQLLACDSGYSFIPSN
TTESV-NNSDLLNLTYLKAILSSLAAAFPLHNNTDSSTVITSKLIKDPRLMKREESMGKD
NTVTGLSEILPFEKSLDFVNSEIN-LSSMPANPASTSEGMPGDQT-ITNGLDASCFRISL
DDSQTQAHNLGSKTYDCTALSKITMTGQCENQ---D-DFSFPMFLSNVVSEAEIQKHKEG
KAQRSQQRDTIPFLTDESSESHD---------SCESV---DICTDKYSGPISPESQFSNF
KTVYETGHQMS-ALFPLQSEGS-IHEYIQNTGKMRSF-TEPEDSA--KHEEKQSLWKGSD
H-SFTNKRKVGPIDNYISLNQD--NKENESLDYLQENCDQILITQGL-EKTK-SLPFTTE
EKCELGHLALEIQNNLT-PRVEKLPQKPPKNSSECKD-NIHTNFAISQKLMELKLEKPD-
QNCVSIMADAFQDAEDIPQTTQLPA--VTSCRDIKTAHD-ANCSIASERLCVQRTNEYDP
VSLGNIQRDCKETPLIN---NKGQHHTQFCITQLNNDVH---LNTDFR-EQRDNDKE---
---SQNEAEMEN-IASSIENNIGNIYGDEKQSFQTHETKFFTN-IGERRVNKDDDSIEIL
SSEEFSTAFNLTSGKK-HVCTESTSLEN---EDPITAIKEKDIQ-NTERTGEHLSSTA-F
LQS---ASSSVHVASHAAAEIADAAMPVVS-TNPEDHQRAQFNETCS-ESTDFGLLSKLK
VSASEINTDENRFHNSFYQTVS-DN---SVLQSFRLDNETEVGSEESDDAFPVSIPQDTH
SHGNVLYEEFEDSYEALKSRIDWEGLLGSSNGEMEVLKSTTRGENWDQHCSEEQSCDFSS
TQDDEAELIEPILLPDLQVTIT-NTFVKGFSPTVESLASKDDFCKYETEAAKSEINEEEE
EEEEEEEVLEFEIHSQCSAENSDHPSENEFGNT-RQESGLASKS-ETSLSFDLS-HNMHE
---NHMSE--KQNRPLLTEPSDGT-TVNKENRCSLTKSK-TSSTDTRSEKETGSRISKRK
P-HTPFRDQKIPDKNLRHHEICEKRRKLTSQDSLECFFLLSQERIKTFSQSEKHIGSVLD
ILNREASLCKSKCLSRKLDRAILHLKEAHRRVHTSLQLITKVGEK-RGGPLPRAYAVICN
SF-WESCDLQGYSSVSERRYHSTKHFLSKRKYNIPGENRTLGFEAD---THVSKHKFYR-
T------NRERLTECLSENV--SGVSSSHTT-IHMREYCDQV-CPESQLALCSVSQSTSQ
S-AYTNSSVRN-SKSSKLQPFSRK-TGCLFSPDCPNETPTKKENRTDTEFSSNISKCEKL
ENHSALDNSK---YTTKVNNSEAKEI-SERNLMSLSCIKENNISFSVDQ-NNDATCTAHT
KVETDTVISVLESKVKRFFDIDIYKPNNLILSGYKGNLEVNFPIEKWATPKESSKPGIIT
GNFLMDPLSQTLITSKKSNSIPQSLSPAPATDSEGESSKSSMATQSITAVDFPAVST---
---IAPHCLQGCGGN--KLQKTEYCSSSKCVHIDGNETDA--ENSEVTVAS-ETEESKD-
----SA-------VKKVFPDDSFLLIKDNIKGSSSKEGIGEKDIQDRKMWKDKQAEKG-K
DSV----HM-NVTE-GSSVKTEYKDQKNNMS-EGCSCLSEKTMQNNLIDSHVQ-IKKATE
A--VSLRNIASNQLNKRK-EE-EGRV-SQDSQY---------------------------
-DSSLHSEVACDSK---PGITGRNHMPHLRGQSEPPKVSPPPPKKSTSYMNEFKEKHCSS
NNLAPTVKLTQILRRADETSSVQILQEESEVCQNILPLFVEAFERKQKCSFKQILISRDL
LVEENLWSNCRHRLKPCAVDSLVELQMMMETIQFIENKKRLLGGEPTFRSLLWYDETLYS
ELLGRPRGFQQQSNFYPAFQGRLKYDAFSELQSYHGQLIELFEETKRGNNSYYAYLKYKR
QIDECEAVMKRCSDCFDFSLSVPFTCGVNFGDSLGDLETLRKSTLSLISMYG-DCPQIDS
CPGKQDHLWIIIEMISSKVNFIKSNEAVNIKIALYGLEHIFFDASKSLVWEEKKQSFCKN
YSER-NKEILLRMNQCAVSKLQKIYDTLSKDLSIEQ-ISTIGLE-NSVIASIKSNAVVNE
ATISIENSRLNG---TLLSHPDICCVSEILDQAEFADVKKLQELTLRCTDDLEIFKKCFQ
LLQEDNIDDLFITEENSLYMMKNYSHKAVILKPAAIETYIEIVMLSETIHFLKNSVAKKL
DKQRFRSMLWFDMSLLPELVHCQEKMTSFSFLKGNPTD-CLWKAIETSISELKKDLDIIY
KCNE-AVNSSYAVRLLSRELEELSEIKNLVKKSEYSISTYINFVPCIASVNYGTTVTELE
YNYRQFSTLLGSITATPRKDVGKMVHTMKVMKTIEHMKIICVKNAQLTISFILCQMLHNR
KTFQP--KRKKNASSHI-NHRKSIRKSSTCG-KVSLVSEYIIKNFSNSSKKRPLTVDKCG
D-SQEQEKDTAVPSCKKQKVGMKHVTEIKREKSPFEHARTMRSHSESENEIGPDSSDSVE
RSHV-SPKQVETQRSVP-----LMNLKD-----SEGEIDLTNISFATSEDFTG-QGKL-S
STKK--RNRNFSAAQAKSEKKTCSPLAIFDQKSIDD-TFSKDQEMPPQKFLKNPPDTAEK
SCPSDIKPGTDASLLLNA----SEPSFCFVSDSHATLEMT---DFEPQDNKILNSSINY-
---TCTSSPEPMHIQNRIPVVQINKARPAKTESKEKYMKDTLNFSTI-PVEASENITLNV
NQTVEYSLSEQQ-----NLQVLAQNAATYLSEIPQSACTPEYDSLSGYSL-ETSYPCSWC
VYRYSS--SSDSSITQTYQGAAFCEEQPPQQPPPGMLTAVTS-----NIQNTPSHLLSSQ
YFEYFAGEPQANDLVPVSDYFPPQTPV-YNFQQPVFSEYTPHQPS--TPYPSSPDLDALL
EVPWTYDPCH-EEPFEPGQ--

--------MATNKMEMKETAKQNTLWQMSST----SEPMLNTR-EVNPLKKFTIPKIRRT
TEKVYLSPCYTNSREYSFIHDTLNQCRLDVSCDLQS-LWQFGDTKLVHNEELEKNFTTKR
S

PF12509 // ENSGT00390000006260_0_Domain_0 (122, 279)

EMRESGRHCRELEEHFCFLALPQSDVAQIYQNGISTRT--STLKILGNPLLGIYMFRHV
DIALNYSHSRSMTVESILIFKV-LFGKVK------KIQPSVDKNKVSLDPSPNFDCHMSR
NAPSLKDTIE-LQAYSSAVYFYEYSVLSKPVDKPRQCL

ENSGT00390000006260_0_Linker_0_1 (279, 2116)

PYAVVTVKFLGSKVDNGYLMTS
LRFLSSGFPKRAERTCSLNNCTVAKR-GKGKDATVIFEHFKKPVDPF---VQENCLCNVL
NSEINPFNSHISNSYGNVQNG-NVSIPETYNGQAEHNLAEIRDTSQVLAHDSDLSLMPSD
AKESV-NGDLLLNWTSLKNILSSLNAAFPLPNNTGSSTVTTSKFIKDPRLMRREESMGEQ
SNTAGLNEILQFEKSLDNVNSEIK---STPSNSASSSEVVPGDCAVLTNCLDAPCFKTCV
NDSQSWAHNTGSEDYDCVPPNKVTMARQCKDQ---G-NFSFPISVSNVVSEVENQNHSEE
KVQRAQQ---------------------------ESG---NAYKKEYNSRISQESQSSDL
KTIYQTGHQMS-TIFPLKKKVS-IDEYLQNTGKMKNS-TDLKDNS--KHEEKQTSWKEID
N-DFTNETKISPMDNYIVLHQE--YKESESHNSFEKSCDKILITQEL-EIPK-SSTSTIK
DKDELDHLALEWQ--IT-PSLESLSQKHPQHSVEYKD-NIHTSLAISQKLMELKLGKIN-
ANCASIITEAFPKPKDIPEAKEMLIDTVISSYNIETAHDNSNCSITRKHVCVHGKNENEP
VSLEDIQRDYKETAYVE---DRGQDHSLFCNSQL-NDIC---LNVNFK-EQRDNYKE---
---SQNEAKE-N-NASSVENNRENIYGDKKQDSHTN--ENFSY-IDEKED-KNYNNIEIL
SSEEFSATFNLICREK-YVSAATALLES--EEDTISAMKQKDTE-NTGRSVEHLASTA-F
PKI---ASSSVCVASNAAVQIASATMPVLS-ISNDEHQINQFKETCSSESPDFGLLVKHR
VSDCEIDKDKNKSQESFHQSIN-EN---LVLQSIELESEIEIELEDCDDAFI--FQQDTH
SHENMLCEEFVTSYKALKSRISWEGILALDNGEMEVLESTAGRENSDQHYSKESNYFYSS
TQSSETELPSPILLPDLQIRIT-NIFRPGFSPTVESLALKDNFCTHVTEATKPEINKE--
----DGEILGFDIYSQPSGENSDYPCEDKVDNI-RQESGPMSKS-EISLSFDLS-HNTDV
---NHRSK-NQNSESLSSEPSNVT-TVDNGSRCFFTKSK-TDYNDTKNKKEVESRISKRK
L-HTSSRDQNI-HEDLRQHKIYGRKRSLTSQDSSECFSSLSQGRIKTFSQSEKHIKSVLN
ILSGEASLCKSKCLSKKLDKAVTHLKKAHRRVHTSLQLITKVGEK-RKGPLPKSYAIICN
NF-WESCDLQDYSSVSQRKYYSTKHFLSKRKYDKRRKKRAPKADISKSLTYVSKHKSYN-
T------SGE--KQCLSRKSMASGVSKSHPT-IHVEEFHNQE-HPESQLPISSTSQSTSQ
S-VYYNSSVSNPSLSEEHQPFSGK-TGCRFSLDHSDEKLIEKENQIDTKFLSSISKYEKL
EKHSANNNVK---DTTKENSCEANQVINESNSVSLSCIKE-NIHYSTGN-DYDATCIGCT
KVKTDVLISVLDSNVKHFLN-DLYQQENLTLSNYKRNLEVKW-----TAPIERCEQSIIT
GNFLMDPLNLTLIASKK-YSIPQL-SASAVTDSEGESSKSYLDKQRILTIDSFAAST---
---TIPCCEQSCRGK--ELLKTEQCSSGNCLHTDGNETNVT-ENYELDIAS-VTEESRS-
-YGENI-------V-KLSSSDSSLLLKDNVKGPSSETCIVKKDTEDRIMWKVKQVEKA-K
DSV----YKSSMTE-GSAVNTEYKNQNNQIS-EES-CLNEKIIKTNLIDSHLS-TKNNTT
E-SVSLKNTVSNPLN

PF15326 // ENSGT00390000006260_0_Domain_1 (2116, 2382)

KTE-K-AEIKV-TNDSQS---------------------------
-DLTLHSEIAYISK---PGILGVNHTPILPAHSETCKVTTLL-KKPASYMSELKEKHCSA
NHTAFIANLSQILQRADEASSLQILQEETKVCLNILPLFVEAFERKQECSVEQILISREL
LVDQNLWNNCKHTLKPSAVDTLVELQMMMETIQFIENKKRRLEGEPTFRSLLWYDETLYA
ELLGKPRGFQQQSNFYPGFQGRLKYNAFCELQTYHDQLVEL

ENSGT00390000006260_0_Linker_1_2 (2382, 2600)

LEETKREKNSYYVFLKYKR
QVNECEAIMEHCSDCFDFSLSVPFTCGVNFGDSLEDLEILRKSTLKLISACE-DSPKVHS
YPGKQDHLWIIIEMISSKVNFIKNSEAVRIKISLYGLEHIFFDAAKNLVWKEKTQSFSKK
YSQKEDKERLLRVNKCAFSKLQKIYDTLSKDLNNEP-ISPVGLEEDTIIASRKSDHPINK
ATIGIENSKFSS---SLLT

PF15326 // ENSGT00390000006260_0_Domain_2 (2600, 2722)

HPDIYCISEILDQAEFADLKKLQDLTLRCTDHLEILKKYFQ
MLQDDNMDNIFITEENVLDVVKNHSHEAILLKPEAIEMYIEIVMVSETIHFLKNSIAKKL
DKQRFRGMLWFDLSLLPELVQCQEKMTSFSFLKDNSTDVCLWKVIESAISELKKDLDIIY
KYDE-AVNRSYAIHLLSRELQELSEIKKLLKNSKYFISTYIDFVPYITSINYGSTMMELE
YNYNQFSTLLKNVMSAPRKDVGKMAHIMKVMKTIEHMKIICAKNAELTISFFLCQMLYNG
RKILQ-LKRKDKMNIHVVKPGENNNKFSISM-MVPPISECINKNISNSSKKRPSTVDKCE
D-SQEQQKNTTVSSCKKLKVDMKGVTKINRENATFKHPRTTGSHPQSENKIVSSSSNNLK
RNHL-TSKKVEMQRSLPGSLLPLENPKDTCTSKSESKIDLT-VSSDAPDHFTGQQENL-N
SMRK--RNVNFSAVETKSDEKDCAAFAICDQKSAHG-TFSPDREILLQKFLKNSPDPSQN
SCLSDINPETDVSLVPDA-SVLSKPIFCLVKDIHTDLEMN-DTVFELQDNDIVNSSIKNS
S---CVTSPEPICIQNKIPALQINKLQPAETESEDKYMKNTSNPNTVHTFGASGHITLNV
NQGAEYSLSEQQ--NDKTSKVLTQNAATYWNELPQSACTPTYNSSEHLFG-TSYPYSAWC
VYHYSS--SNGNGITQTYQGITSYELQS---PPSGLLTTIASGQGAQCAQGAHSNLLYSQ
YFTYFAGEPQANGFVPVNGYFQSQIPA-YNFQQPVFSQYASHQPLPQTTYPYLPNRDVPP
EVPWVYAPWH-QESFHPQH--

--------MTSNNMEINENDKYKSP---------DSESLWTMDAEASAGKKFTIPKIRRT
TEKVYLSSCYTNTREYGFIHGILKQCRLDLSCDLQF-TWQFGETKLVRNEYLEKQFAAKR
S

PF12509 // ENSGT00390000006260_0_Domain_0 (122, 279)

EMREGGRHSRELEEHFCFLALPQSDVVDIYQSGLSVGT--SPLRILGNPLLGVYLFRHV
DIALRHAYSRSIAVESIMIFKV-FFGRIK------KIQPSMDKNKVSLDPSPNFDCHMSR
NMPSLKDTIE-LQAYNSMVYFYEYDFFSRPVDKPRQCLPYAIVTVKCIGQKAGNGQLITS
LRFPSTGFPKRLERACSLNNCTIAKRIGKGKDATVIFEHFRKPVDPF---VQENCPCKAL
NSEMSPSSSDTSNSYGNVQNG-NNSMLEAYNRQTEN-SSNLRDASQVYTHNSGFSFIPTD
NTASG-NGDL-FSVTYLRSILSSISAAFPSHNNTGSSTVITSKLIKDPRLMKREQSVRNK
NNTAGLSDVLPFDKSLGRVDSQIK-LACMPISSISSSE-VPADHTI-TSCLNASCFKFSS
ESSHYQAHNSSSNGHDCIASSSIAVTEQFKEQ---H-SSSFPSSLSNAYSDVRKQKHSEE
HVQRAQMRSNVPVLTAPSSGPQN---------SDE---SENTCSNNSQGHFSQESPSSDI
NSIYEVGHQMS-TVFSAQEKGN-LCEYIQDTGMMRTS-INPEDST--KDGVNHTWCKETV
---LTNETVSSAIDNSNTLYQE--HKEGGNLNALSSNCEKIGVTHKL-QMPK-FPISSTR
DKNELDCAALELECSLI-PTVECLSQKYPQHSLEHED-NTNTNFAMTQGLIELKTVQNN-
QNFDNILSDAFQEAKDVPLASEKLIDRVISSAAIDISLDSSVCNIIGDYTCVQRENENGA
VSPYNCHKE--EAANVK---DGVQDHSLSYDAELSCGLN---SKINLQ-EQRT--DS---
---NPNEAKE---------HNTDNINGNEKQDCHAN--EHFTN-IVEMREIKCNTKVEIL
NSEECF-TFNSFWGKN-SKPAETASSES---E----AVEQRHAP-NDQRGLEHLVST--F
PEI---EGSSMCIASNATKQVVGTTVLTVS-TSLGNHQEDELKEICSSESSDLGL-VKHS
ISECEIDTDKDKLQD-FHQLVN-EN---SALK-TVLGSEIEVDLEEHANASV--FQ-NMH
SQENDLCEEFD-VYESLKSRIDWEGLFGSSYEEMETSSFARR-EGTDQHSSPEWNCVSFC
SQ-DKRELHNPIFLPDLQVTIT-NLLRLRISPTDESLELKDNFYKPVTESTEPETNKE--
-----GNASGFGMCSQPPGENSSFSCANKFGNS-VQESRDVSKS-GNSYSSNSS-HSTHV
---DQGSG-KPNNDSLSTEPSNVT-VMNDKSKC-PTKSK-PVFNDT--------------
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-TF--LFCIISTERTCSLNNCTVAKRIGKGKDATVIFEHFGKPVDPF---VDESCLYSTL
NSDINLPNSDPSNSYGNVQNG-NISNFDTYSGQSEN-SSEIRDTSQV--PDSSLSFMPRE
S---G-NEDLLLNLTYLKSILSSISTPVLPQNNTASSTVITSKLIKDPRLMKREESMGKQ
SNITGLSDGVPIDRNLDHVSSEIN-LSSIPTVSAS-SEVVPSGDTILANCLDTSCFTCSF
EGSQSQARSMMSENYDCIPSNKNVIVEQYSDQ---G-KIYFPISLSNVVSEVENQNHSEE
KAQRTKERS------TQNNESYN---------YYKSV---NTCTRESKDHISQESQAYNF
ITMHQIGHQIS-TVAPLQKKGS-IDEYIENTGKIRTF-IDSEDSS--KHEGRQTWWNETN
N-YLTNETKISPIDNCLSLPQE--YKEDERLDSLVDNHENTLITEEV-ELSK-SPISTKK
DKDKVDDLALQLESNST-PSIECHSPKHLQHFLEYDS-GIHQSFTIAQKLIELKLEERD-
QNCFNIITDAIQEAKDIPQMKELLVDTVISS-AVETALDSSERSTTEECMSVQKKTENET
VSLENIQKDCNETLNIE---NEYQDHILFCNANLNDDIY---LNIKFI-EQGDNDKE---
---NQNEAREEY---------------SEKQGFHTH--NFFTN-ISKKVENKNYQ-VEMS
SPKEFS-AFNLIWRKR-GISAETGLLKN-----KDDVIKQKDTQ-NIGKNVENLAFTT-V
SEN---STASLD-VSNAAVQVTSTTISTLS-TNHEDHQKFLLNETCISKSPDFGLFVTHK
ASDCEIYMDKGNSQDSFYPAVD-EN---LFLQNFELESEIEIETEEYDDAFL--FQQGIH
SHGNVLYDEIEDAYEILKSRIDWEGLFGSSFEE---LEASFTRENSEQPYLKKNGCVYSS
TPKATRELLNP-VLPDLQIRITNNLFRPGFNHTDDSLTINDNFYKCINEVTKPEIYEE--
------RTPGFEMYSQSLDENSSYSCENKLDDL-MQDSRLASKF-QISYSSNLS-HSIHV
---NHATE-KPNSEFLSTEHSNII-PVIEN-KCSSTNSKNYDFTDTR-NKGMESRISKRK
L----------ANKDLRHHEICGKKKRQTSQDSSEHFSLLSQGRIKTFSRSERNIRNVLD
ILNSEASLCKSKRLSRKLDKAVLHLKKAHRRVHTSLQLISKVGEI-KKGPLPKAYAIICN
NF-WESCDLEGYSS--ERRLY-SKHFFSKRKCDKQGEKRAIGFDTDKSLVRMSKHRSNK-
T------NGDRILECFSKKRVASSVSKSHTS--VHRELCDQEQHPESQLLLSSTSQSTSQ
S-ECDDS--RN-PASSDLHPFSEK-TEYLLY---PDEKITEKEHVD-KK-L-SNNKYESL
ENHSIHGNMN----DATENNSETNAEINESYSVSLSCIKEKNGSCGTDK-NCDTTCIVKA
DIKV---TSLLKSEMKHVFNADVYKQDDLTLSGCKRN-EVIFPVVEWAAPNESSTSR---
---IMDPLNLSLTK----------------------------------------------
------------------------EFSSNCFHIDMNETNVPPEHPELDLMP-VIEENKY-
---EKN-------MKKLSSKD-DLPLKCNVKES-SKTCVAQNDIQDTKFRKEQ-TEKV-I
-SV----YKSNMYE-GSPVRIENQNQKTKPS-----HLSLKTSKST--DSHPLLMNKIPQ
A--ISLNNKDSHQ

PF15326 // ENSGT00390000006260_0_Domain_1 (2114, 2382)

PKGN--KEGKTKA-SNDFQS---------------------------
-D--------CISK---PSILRTNHMPIPHTHSETSKVAILQ-KTPISYMKKH-----SD
NHTSFIAELSQILQRADEASSLEMLEKETKVCQDILPLFVEAFERKQACALEQILISREL
LVGQNLWNNCRHKLKPCAVDTLVELQMVMETIQFIKNKKRLLEGEPTFRSLLWYDETLYS
ELLSRPRGYQLQSNFYPAFQGRLKYNAFYELQSYHNQLIEL

ENSGT00390000006260_0_Linker_1_2 (2382, 2602)

LAETKRENSSYYAFLKYKR
QINECEAIMKHRSDCFDFTLSIPFTCGVNLGDSLGDLEILKKSTLKLIDIHG-DSPKVHS
YTGKQDHFWIIIEMIASKVNFIKNNEEASIKTSLYGLEHICFDAAKNLVWKAKRYSFSKN
--SQKNKEVILEMNECAFSKLQSIYDTLSNGLNNEP-TSSIGLDEDTVIFSRKSDDVI--
---MTENSSLNS---TLFSRP

PF15326 // ENSGT00390000006260_0_Domain_2 (2602, 2721)

DICCISEILDQAEFADVKKLQELTLRCTDHLEILKKYFQ
ILQEDNIDNIFITEENILDVLRNDNKGAIILKPAAIETYIEIVMLSETVHFLKNSMAKKL
NNQRFRGMLWFDLSLLPQLIHCQEKMASFSFLNEGATG-CLWKVIETAISGVMEDLDIIY
KYNG-AVNCSYALHLFSRELNELSEIKKLVVTSKYSISTYIDFVPCIASINYGNTVTELE
HNYSQFSMLLKSTMSVPQKDLGKVAHITKVMKTIEYMKIICAKDAKLTTSFILHQILHNR
KDTSQ-LKRKEKINVDITKREENI-KPSTSL-KTPSISECLMKTMSHPTKKRPIAIDKCE
D-SQENETTTKVSSCKKQKSKS-------------------------ENEP----GSSLK
RNYV-SSKKDELKKSVSGSLLPLKNLQESGTSKSESKIDLTDSSSDVSEYLAGQQENL-N
S-----------------------------------------------------------
-------------------TVVSEASLHSARDIYTNLDLN-DTIFEHQDNKIINLSIKDC
T---STTSPEPIYIQNKIPVLQVKKTQPVTTES--QHMKDRLNPSTV-PFGAPRSSI-DV
--------------NEEHPKTLDQTADTSWNEHAQSECTSIYNSSEYSFG-TSYPYYACY
VYQYSS--SNGSAITHTYQGVTSYEVQP---PPPGIFTTITN-----TVQNTHSSLQYSQ
YFSYFAEQPQANAFVLENGYFRPQMPISYNFQQPAFSQYASYQPLPQAVYRYPPNAGALP
QVPWTY---------------