Query Results 

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MSSNDSSLMAGIIYYSQEKYFHHVQQTAAVGLEKFSNDPVLKFFKAYGVLKEEHIQDAIS
DLESIR-HHPDVSLCSTMALIYAHKRCE--IIDREAIQELEYSLKEIRKTVSGTALYYAG
VFLWLIGHHDKAKEYIDRMLKISRGFR----EAYVLRGWVDLTSDKPHTAKKAIEYLEQG
IQDTKDVLGLMGKAMYFMMQQNYSEALEVVNQITVTSGSFLPALVLKMQLFLARQDWEQT
VEMGHRILEKDESNIDACQILAVHELAREGNMTTVSSLKTQK----ATNHVRNLIKALET
REPENPSLHLKKILVV-SRLCGSHQVILGLVCSFIERTFMA-TPSYIHVATELGYFFILK
NQVKEALLWYTEAMKLDKDGMAGLTGIILCHILEGHLEEAEHQLEF-----LKEVQKSL-
---GKSEVLIFLQALLTSKKHKGEQETTALLKEAVELHFSSMQGLPLGSEYFEKLDPYFL
VCIAKEYLLFCPKQPRLPGQIVSPLLKQVAVILNPVVKAAPALIDPLYLMAQVRY

PF14559 // ENSGT00390000005979_1_Domain_2 (596, 634)

YSGEL
ENAQSILQRCLELDPASVDAHLLMCQIYLAQGNFGMCFHCLELGVSHNFQVR--------
-------DHPLYHLIKARALNKAGDYPEAIKTLKMVIKLPALKKEEGRKF-LGPCLQTSQ
RASILLELVEALRLNGELHEATKVMQDTINEFGGTPEENRITIANVDLVLSKGNVDVALN
MLRNISPKQSCYMEAREKMANVYLQTLRDRRLYIRCY------RELCEH----LPGPHTS
L

PF13432 // ENSGT00390000005979_1_Domain_5 (842, 900)

LLGDALMSILEPEKALEVYDEAYRQNPHDASLASRIGQAYVKAHQYTEAIEYYEAAQK

ENSGT00390000005979_1_Linker_5_6 (900, 907)

I
NGQDFL

PF13181 // ENSGT00390000005979_1_Domain_6 (907, 933)

CCDLAELLLKLKKINKAEKVLKQ-AL

ENSGT00390000005979_1_Linker_6_7 (933, 1022)

EHD--I-VQDIPSMMNDVKCLLLLA---
KVYESHKK---EAVIETLNKALDLQSRILKRVPLEQPEMIPSQKQLAASICIQF---AEH
Y

PF14559 // ENSGT00390000005979_1_Domain_7 (1022, 1089)

LAEKEYDKAVRSYKDVFSYLPT-DNKVMLELAQLYLLQGHLDLCEQHCAILLQTEQNHE
TASVLMADLMFRKQKHEAAINLYHQVLEKVPDNFLVLNKLIDLLRRSGKLE-DIPAFFEL
AKKVSSRVPLEPGFNYCRGIYCWHIGQPNEALKFLNKARKDSTWGQSAIYHMVQICLNPD
NEVVGGEAFENQGAES-NY-TEKKELEQQGVSTAEKLLREFYPNS-ASSQTQLRLLQGLC
RLATKEKANMEAALSSFIQIAQAEKDSVPALLALAQAYVFLKQIPKARMQLKRLAKAPWV
LSEAEDLEKSWLLLADIYCQGSKFDLALELLRRCVQYNKSCYKAYEYMGFIMEKEQSYKD
AVTNYKLAWKYSHHA----NPAIGFRLAFNYL----KDKKFVEAIEICHDV---------
-----------------------LREHPNYPKIREEILEKARRSLRP

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MSSDDSSLMASIIYYCQEKYFHHVLQAANVGLERYSCDPVLQFFRAYGVLGEDRIHDAIS
ELESLQ-SHPDTSLCAVIALLYAHKCCD--TIDAEAIQELDSSLKEIRRTASGMALYYAS
LFLWFMGHHDKAREYVDHMLKVSSGSK----EGYVLKGWVDLTSNKPHVVKKSIKYLEQG
TQDTKDVLGLMGKAKYFMTQQNFSGALEVVNQVTLAYSNFLPALVLKMKLFLARQDWEQT
IETGQRILEKDENNIDAWQILAVHELVKEGNTDRA------------ADRVRNLIKALET
GEPQNPNLHLKKILAV-SRLCGRHQVVHRLVSGFLERTFMA-TPSCALVATELGYLFILQ
QQVKEASLWYKEAMKLEENRLAALAGSIWCQILQGQLEEAAHQLEFLKEVQ---------
LSLGKSEVLVFLQALVAAKKQKLEQEATALLKEAVELHFSNMQGLALSPEYFEKLDPLFL
VCIAKEYLHFCPKQPRSPGQLVSPLLKQVAMILSPVVKVAPAMMEPLFVTAQVKFLSGEL
ENAQSTLQRCLELDPTFVDAHLLMSQIYLAQGNFAMCSHCLELGVSHNFQVR--------
-------DHPLYHFIKARALNKTGDYAEAIKTLKMIIKVPTSKAEEGRKS-RGPSVRPSE
RASILLELVEALRLNGELHEATKIMQDAINEFSGTPEEMRITVANVDLALSKGNADLALN
MLRGITPKQPCYTEAKEKMASIYLHTRKDVRLYIGCY------MELCEH----LPGPHSS

PF13432 // ENSGT00390000005979_1_Domain_5 (841, 902)

LLLGDAFMNIQEPEKALEVYDEAYRKNPHDASLVSRIGQAYVKTHQYAKAINYYEAAQKI
S

ENSGT00390000005979_1_Linker_5_6 (902, 907)

GQDFL

PF13181 // ENSGT00390000005979_1_Domain_6 (907, 935)

CCELAELLLKLKKYHKAEKVLKQ-ALER

ENSGT00390000005979_1_Linker_6_7 (935, 1022)

D--SGVKDIPSLMDEVKCLLLLA---
KVYKSHKK---EDVMETLNQALDLQSRILKRVPLEQPEMIPSQNQVAASICVQI---GEH
H

PF14559 // ENSGT00390000005979_1_Domain_7 (1022, 1088)

LADKDYDSAMKSYKDALAYSPT-DSKVVLELAQLYLLQGQLDLCEQHCAPLLEMEQTHE
RAAVVLADLMFRKQNYETAINLYRQVLEKAPDNFLVLNKLIDLLRRSGKLE-EAPAFFEL
AKKVSSRVPLEPGFNYCQGIYCWHIGQPNEALRFLNKARKDSTWGQLATCYMVQICLNPD
NEIVGGEAFESLVGDS-NS-ASRKESQQHGVRTAEKLLREFYPHS-ESGQTQLRLLQSLC
LLATREKANIEVALGAFIEMAQAEKDNIPALLAMAQAYVLLKQVPKARTQLKRLAKVPWM
LDEAEDLE

PF13181 // ENSGT00390000005979_1_Domain_9 (1329, 1360)

KSWLLLADIYCQGGKFDLALELLRRCLQYNKSCCRAYEYMGFIMEKEQSYKD
AATNYELAWKYSHQA----NPAIGFKLAFNYL----KDKKFVDAIEVCHS----------
----------------------VLTEYPNYPKIREEILEKAQGSLRP

------------------------------------------------------------
-ATVSSSTQAGIIYYSHEKYFRHVQHAAAMGLEKFSNDPVLQFFKAYGVLREERIQEAIS
DLENIR-NHPDVSLCAIMALIYAHKRCE--AIDREALQELENSLKEVRKTAG

PF00515 // ENSGT00390000005979_1_Domain_0 (173, 206)

GAALYYAG
LFLWLMGRHDKAKEYIDRMLKVSSGSR----EGYVLRGWMDLTSDKPHTVKKSIKYLEQG
IQDTKDVLGMMGKATYLMMQQNYSGALEVVNQMAVASAGFLPALVLKMQLFLARQDWEQT
VETGQRILEKDESNIDACQILAVHELAREGNVTKA------------AERVRNLIKALEM
REPQNPSLHLKKILVI-SRLCGRHQPILRLVCGFIERTFLA-TPSYAHVATELGYLLILR
DQVKEASLWYCEAMKLDENSIAALTGIIWCQILEGHLEEAEHQLEFLKAVQ---------
QSLGKSKVVVFLQALLASKKHEVEQEATTLLKEAAELHFSNMQGLPLGPEYFERLDPPFL
VCIAKEYLSFCPKQPRSPGQIVSPLLKQAAVILNPVVKAAPAL

PF00515 // ENSGT00390000005979_1_Domain_2 (584, 617)

MEPLYLSAQVKYLSGEL
ENAQSTLQRCLELDPTSADAHLLMAQIHLAQGNFAMCSHCLELGVSHNFQVR--------
-------DHPLY------------------------------------------------
------------------------------------------------------------
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--LNWEGCEAGIIYYSQEKYFHHVQQAAATGLEKFSNDPVLQFFKAYGAFREEHIQDAIS
SLESLR-NHPDVSLCSIMALIYAHRCCK--TIDQEAIQELESSLKEIRKTAS

PF00515 // ENSGT00390000005979_1_Domain_0 (173, 206)

WIALYYAG
LFLWLMGRHDKAKEYVDRMLQLSNGAR----EGYVLKGLVDLTSDKPHTAKKAIKYLEQG
VQDNKDVLGLLGKAMYHMTQQNYSGALEVVNQITVVSESFLPAWILKMKLFLARQDWEQT
VETGHRILEKDKRNIDAYQILAVHELAREGNMTTA------------ADHIRNLIKALET
REPQNPSLHLKKIIVV-SRLCGRHQMILQLVCSFIERTFLA-APTYTHLAIELGYLFILQ
DQVKEASVWYSEAMKVDENSVAALTGIIWGQILEGHLEEAEHQLEFLKEVQ---------
QSLGKSEVLVFLQALLASKRHKGEQEVTALLQEAAELHFSYMQGLPLGPEYFEKLDPLFL
VCIVREYLFFCPKQPRSPGQIVSPLLKQVAMILTPVVKAAPALIGPLYVMAQVKYLSGEL
ENAQSTVQRCLELDPASVHAHLLKAQIYLAQGNFAMCSHCLELGVSHNFQVR--------
-------DH

PF00515 // ENSGT00390000005979_1_Domain_3 (670, 699)

PLYHFIKARALNKSGDYPEAIKTLKMIIKLPTLKAEEGKKV-RGPSVGPSE
RASILLELADALRMNGELHEATKVMQDAIDEFSGTPEETRITIANVDLALSKGNVDMALS
MLRNITPKQPYYTEAKEKMASIYLHTRKDVRLYIGCY------RELCEH----LPGPDTS
LLLGDAFMNILEPEKALEAYDEAYRKNPHD

PF00515 // ENSGT00390000005979_1_Domain_5 (871, 904)

ASLVSRIGRAYVKAHEYTKAINFYEAAQKI
SGQDFLCCDLAELLLKLKKFNKAEKVLK--ALEHD--V-ATDIPSMMNDVKCLLLLA---
KVYKSHKK---EDVLETLNKALDLQSRILKRVPLEQPEMIPSQKELA

PF00515 // ENSGT00390000005979_1_Domain_7 (1008, 1045)

ASICFHF---GEH
YVAEKEYAKAVRSYKDALSYSPT-DNKVGSSKPD------PTPSLRARCPAELPAGHSRA
QAVAMTADLMFRKQEYEAAINLYHQVLEKAPAAVTATLRIIILRSQLSALETLKRLFFEL
PKSMSSRVLLEPGFNYCTGIYHWHIGQPTEALKFLNKARKDSTWGQSATCYMVQICLNPD
NEIVGGEAFYNFVPES-IS-SSRKESEQLGVRTAEKLLREFHPHT-AWGQTQLQLLQGLC
LLATKEKANMEAALGTFIQMAQAERDSVPALLAMAQAYMLLKQVPKARTQLKRLAKAPWA
LAEAEDLRE-LAPAADIYCQ----------------------------------------
------------------------------------------------------------
-----------------------------------------------

------------------------------------------------------------
MNSNDSSLMAGIIYYSQEKYFHHVQQTAAVGLEKFSNDPVLKFFKAYGVLKEEHIQDAIS
DLESIR-HHPDVSLCSTMALIYAHKRCE--IIDREAIQELEYSLKEIRKTVSGTALYYAG
VFLWLIGHHDKAKEYIDRMLKISRGFR----EAYVLRGWVDLTSDKPHTAKKAIEYLEQG
IQDTKDVLGLMGKAMYFMMQQNYSEALEVVNQITVTSGSFLPALVLKMQLFLARQDWEQT
VEMGHRILEKDESNIDACQILAMHELAREGNMTTVSSLKTQK----ATNHVRNLIKALET
REPENPSLHLKKILVV-SRLCGSHQVILGLVCSFIERTFMA-TPSYIHVATELGYFFILK
NQVKEALLWYTEAMKLDKDGMAGLTGIILCHILEGHLEEAEHQLEF-----LKEVQKSL-
---GKSEVLIFLQALLTSKKHKGEQETTALLKEAVELHFSGMQGLPLGSEYFEKLDPYFL
VCIAKEYLLFCPKQPRLPGQIVSPLLKQVAVILNPVVKAAPALIDPLYLMAQVRYYS-EL
ENAQSILQRCLELDPTSVDAHLLMCQTYLAQGNFGMCFHCLELGVSHNFQVR--------
-------DHPLYHLIKARALNKAGDYPEAIKTLKMVIKLPALKKEEGRKF-LGPSLQTSQ
RASILLELVEALRLNGELHEATKVMQDTINEFGGTPEENRITIANVDLVLSKGNVDVALN
MLRNISPKQSCYMEAREKMANVYLQTLRDRHLYIRCY------RELCEH----LPGPHTS
L

PF13432 // ENSGT00390000005979_1_Domain_5 (842, 900)

LLGDALMSILEPEKALEVYDEAYRQNPHDASLASRIGQAYVKANQYTEAVEYYEAAQK

ENSGT00390000005979_1_Linker_5_6 (900, 907)

I
NGQDFL

PF13181 // ENSGT00390000005979_1_Domain_6 (907, 933)

CCDLAELLLKLKKINKAEKVLKQ-AL

ENSGT00390000005979_1_Linker_6_7 (933, 1022)

EHD--I-VQDIPSMMNDVKCLLLLA---
KVYESHKK---EAVIETLNKALDLQSRILKRVPLEQPEMIPSQKQLAASICIQF---AEH
Y

PF14559 // ENSGT00390000005979_1_Domain_7 (1022, 1089)

LAEKEYDKAVRSYKDVFSYLPT-DNKVMLELAQLYLLQGHLDLCEQHCAILLQTEQNHE
TASVLMADLMFRKQKHEAAINLYHQVLEKVPDNFLVLNKLIDLLRRSGKLE-DIPAFFEL
AKKVSSRVPLEPGFNYCRGIYCWHIGQPSEALKFLNKARKDSTWGQSAIYHMVQICLNPD
NEVVGGEAFENQGAES-NY-TEKKEVEQQGVSTAEKLLREFYPNS-ASSQTQLRLLQGLC
RLATKEKANMEAALGSFIQIAQAEKDSVPALLALAQAYVFLKQIPKARMQLKRLAKAPWV
LSEAEDLEKSWLLLADIYCQGSKFDLALELLRRCVQYNKSCYKAYEYMGFIMEKEQSYKD
AVTNYKLAWKYSHHA----NPAIGFRLAFNYL----KDKKFVEAIEICHDV---------
-----------------------LREHPNYPKIREEILEKARRSLRP

MEGPARPSASSTLQAGATPPCTPATGFTYRIPLCSPKPSSSSSILHCASQTGSRVLGALS
FLNHVFLTQALIIYYSQEKCFRHVQQAASMGLERYSNDPVLQFFKAYGVLGEDHIHDAIS
ELESLQ-SHPHMSLCSVMALLYAHKCCD--TIDAEAVQELESSLKEIRKTASDTALYYAS
LFLWLTGHHDKAREYVDHMLKVCNGSK----EGYVLKGWVDLTSSKPHVVKKSIKYLEQG
TQDTKDTLGLMGKATYFMTQQNFSGALEVVNQVTVASGNFLPALVLKMRLFLARQDWDQT
IETAHRILEKDESNIDAWQTLTVHELVREGNTATA------------TDHVRSLIKALET
GEPQNPSLHLKKIVVV-SRLCGRHQAVQRLVSGFLERIFMA-TPSCAAVATELGYLFILQ
QQVKEASLWYKEAMKLEENRLSALAGSIWCQILQGQLDEAAHQLEFLREVQ---------
QSLGKSEVLVFLQALVASKKQKLEQEATALLKESVELHFSNMQGLALGPEYFEKLDPLFL
VCIAKEYLHFCPKQPRSPGQLLSPLLKQVSMILSPVVKVAPGMLDPLFVTAQVKFLSGEL
ENAQSTLQRCLELDPNFVDAHLLMSQIYLAQGNFAMCSHCLELGVSHNFQVR--------
-------DHPLYHFIKAKALNKTGEYAEAIKTLKMIIKLPTIKAEDSRKP-RGPSVQPSE
RASILLELVEALRLNGELHEATKVMQDAINEFSGTPEEVRITIANVDLALSKGNVDLALS
MLRGITPKQPCYTEAKEKTASIYLNIRKDVRLYIGCY------MELCEH----LPGPHSS

PF13432 // ENSGT00390000005979_1_Domain_5 (841, 902)

LLLGDAFMSIQEPEKALEVYDEAYRKNPHDAILVSRIGQAYMKTHQYSKAINYYEAAQKI
S

ENSGT00390000005979_1_Linker_5_6 (902, 907)

GQDFL

PF13181 // ENSGT00390000005979_1_Domain_6 (907, 937)

CCELAELLLKLKKYHKAEKVLKQ-ALERD-

ENSGT00390000005979_1_Linker_6_7 (937, 1023)

SSGVKDIPSMMNEVKCLVLLA---
KVYKNHKK---EDVVETLNQALDLQSRILKRVPLEQPEMIPFQKQLAASICIQM---GEH
RL

PF14559 // ENSGT00390000005979_1_Domain_7 (1023, 1088)

TEKDYESALKSYKEALSYAPT-DNKVALELAQLHLLLGQLDLCEQCCSPLMMMEQTHE
RAAVMLADLMFRKQNYETAINLYRQVLEKAPDNFLVLNKLIDLLRRSGKLE-EAPAFFEL
AKKVSSRVPLEPGFNYCQGIYCWHIGQPNEALRFLNKARKDSTWGQIATCHMVQICLNPD
DEIVGGEVFESLVTDS-NS-ASRKESQQHGVRTAEKLLREFYPHS-DSGQTQLRLLQSLC
LLATREKANVETALGAFIEMAQTEKDSIPALLAMAQAYMLLKQVPKARTQLKRLAKIPWT
LNEAEDLEK

PF01535 // ENSGT00390000005979_1_Domain_9 (1330, 1354)

SWLLLADIYCQGGKFDLALDLLRRCLQYNKSCCKAYEYMGFIMEKEQSYKD
AATNYELAWKYSHQA----SPAIGFKLAFNYL----KDKKFVDAIEVCHS----------
----------------------VLMEHPNYPKIREEILEKAQGSLRP

------------------------------------------------------------
MSNNDSSLMAGIIYYSQEKYFRHVQQAAAAGLEKFSNDPVLQFFKAYGVLREERIQDAIS
ELESIR-NHSDVSLCSIMALIYAHKCCE--TIDREAIQELEGSLKEIRKTAG

PF00515 // ENSGT00390000005979_1_Domain_0 (173, 206)

GTALYYAG
LFLWLMGRYDKAKEYIDRTLKVSSSSK----EGYVLRGWMDLTSDKPHSVKKSIKYLEQG
IQDTKDVLGLMGKATYFMMQQNYSGALEVVSQITMASGSFLPAYVLKMRLFLARQNWEQT
VETGQRILEKDESNIDACQILAVHELAKEGNMTTVSSFKTQK----AVDHVKNLIKALEI
REPQNPSLHLRKILVI-GRLCGRHQVILRLVCSFIERTFMA-TPSYAHVATELGYLFILR
DQVKEASLWYSEAMKLEESSVAALTGIIWCQILEGHLEEAEHQLEFLKEVQ---------
QSLGKSEVLVFLQALLASKKHKGEQEATELLKEAAELHFSNMQGLPLGSEYFERLDPLFL
VCIAKEYLLFCPKQPRLPGQIISPLLKQISVILNPVVKVAPALIDPLYLMAQVKYLSXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXX----------------XXXXXXXXXXXXXXX
XXXXXXVDHPFYL--ISRTLNKSGDYPEAIK-LKMIVRLPTLKNEEGKKF-RGLSLRPSE
RVSILLELADALRLNGELHEATKVMQDAINEFSGTPEEIRITIANVDLALSKGNVDMALS
MLRNITPRQPCYTEAKEKMASIYLQTRKDVRLYIGCYRXXXXXXXXXXXXXXXXXXXXXX
XXXXX------XXXXXXXXXXXXXXXXXXX-----XXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXX----XXXXXXXXXXX-XXXXX----XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXALDLQSRILKRVPLEQPEMIPSQKQLA

PF00515 // ENSGT00390000005979_1_Domain_7 (1008, 1044)

ASICIQF---GEH
YLAEKEYTKAVRSYKDALSYSPIN-NKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXX
XXXXXXXXXXXXXXXX-XXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSCCKAYEYMGYIMEKEQSYKE
TTL---ELWKYSHHA----NPAIGFKLAFNYL----KDKRFVEAIEVCHS----------
----------------------ILREHPNYPKIREEILEKAQGSLRP

------------------------------------------------------------
MSSNDSSLMAGIIYYSQEKYFHHVQQAAAVGLEKFSNDPVLKFFKAYGVLKEEHIQDAIS
DLESIR-HHPDVSLCSTMALIYAHKRCE--IIDREAIQELEYSLKEIRKTVSGTALYYAG
LFLWLIGRHDKAKEYIDRMLKISRGFR----EAYVLRGWVDLTSDKPHTAKKAIEYLEQG
IQDTKDVLGLMGKAMYFMMQQNYSEALEVVNQITVTSGSFLPALVLKMQLFLARQDWEQT
VEMGHRILEKDESNIDACQILTVHELAREGNMTTVSSLKTQK----ATNHVRNLIKALET
REPENPSLHLKKIIVV-SRLCGSHQVILGLVCSFIERTFMA-TPSYVHVATELGYLFILK
NQVKEALRWYSEAMKLDKDGMAGLTGIILCHILEGHLEEAEYRLEF-----LKEADIGTE
TRSSLPQVLIFLQALLMSRKHKGEEETTALLKEAVELHFSSMQGIPLGSEYFEKLDPYFL
VCIAKEYLLFCPKQPRLPGQIVSPLLKQVAVILNPVVKAAPALIDPLYLMAQVRY

PF14559 // ENSGT00390000005979_1_Domain_2 (596, 634)

YSGEL
ENAQSILQRCLELDPASVDAHLLMCQIYLAQGNFGMCFHCLELGVSHNFQVR--------
-------DHPLYHLIKARALNKAGDYPEAIKTLKMVIKLPALKKEEGRKF-LRPSVQPSQ
RASILLELVEALRLNGELHEATKVMQDTINEFGGTPEENRITIANVDLVLSKGNVDVALN
MLRNILPKQSCYMEAREKMANIYLQTLRDRRLYIRCY------RELCEH----LPGPHTS
L

PF13432 // ENSGT00390000005979_1_Domain_5 (842, 900)

LLGDALMSILEPEKALEVYDEAYRRNPHDASLASRIGQAYVKAHQYTEAIEYYEAAQK

ENSGT00390000005979_1_Linker_5_6 (900, 907)

I
NGQDFL

PF13181 // ENSGT00390000005979_1_Domain_6 (907, 933)

CCDLGKLLLKLKKVNKAEKVLKQ-AL

ENSGT00390000005979_1_Linker_6_7 (933, 1022)

EHD--I-VQDIPSMMNDVKCLLLLA---
KVYKSHKK---EAVIETLNKALDLQSRILKRVPLEQPEMIPSQKQLAASICIQF---AEH
Y

PF14559 // ENSGT00390000005979_1_Domain_7 (1022, 1089)

LAEKEYDKAVRSYKDVFSYLPT-DNKVMLELAQLYLLQGHLDLCEQHCAILLQTEQNHE
TASVLMADLMFRKQKHEAAINLYHQVLEKAPDNFLVLNKLIDLLRRSGKLE-DIPAFFEL
AKKVSSRVPLEPGFNYCRGIYCWHIGQPNEALKFLNKARKDSTWGQSAIYHMVQICLNPD
NEVVGGEAFENQGAES-NY-MEKKELEQQGVSTAEKLLREFYPHS-DSSQTQLRLLQGLC
RLATREKANMEAALGSFIQIAQVEKDSVPALLALAQAYVFLKQIPKARMQLKRLAKTPWV
LSEAEDLEKSWLLLADIYCQGSKFDLALELLRRCVQYNKSCYKAYEYMGFIMEKEQSYKD
AVTNYKLAWKYSHHGPHHDPRTQGFKLAFNYL----KDKKFVEAIEICNDV---------
-----------------------LREHPDYPKIREEILEKARRSLRP

------------------------------------------------------------
------------ASVSSAQAWKQGALDLREGRE----------RNLVHALSTDHIHDAIS
ELESIQ-SHPDMSLCSIIALLYAHKCCD--TIDREAVQELESSLKEIRKTASDTALYYAS
LFLWLIGHHDKAREYVDHMLKVCSGSK----EGYVLRGWMDLTSSKPHVVKKSIKYLEQG
AQDTKDMLALMGKATYFMTQQNFSRALEVVSQITVASGNFLPALVLKMRLFLARQDWEQT
IETAHRILEKDENNIDAWQILTVHELVREGNTATA------------TDHVRSLIKALET
CEPQNPSLHLKKMVVV-SRLCGRHQVVQRLVSGFLERIFMS-TPSCAPVATELGYLFILQ
QQVKEACLWYKEALRLEENGLAALAGSIWCQILQGQLEEAAHQLEFLREVQ---------
LSLGKSEVLVFLQALVASKKPTLEQEATVLLKEAVELHFSSMQGLALSPEYFEKLDPLFL
VCIAKEYLQFCPKQVRGRPTVMAGATQKTE---------------TRALPAFGCVFLGEL
ENAQSTLQRCLELDTTFVDAHLLMSQIYLTQGNLAMCSHCLELGVSHNFQVR--------
-------DHPLYHFIKARALNKAGDYNEAIKTLKMIVKLPTTKAEEGRKP-RGPSVRPSE
RASILLELVEALRLNGELHEATKIMQDAINEFSGTPEEMRITVANVDLALSKGNVDLALS
MLRGITPKQPCYTEAKEKMASIYLNNRKDARLYIGCY------MELCEH----LPGPHSS

PF13432 // ENSGT00390000005979_1_Domain_5 (841, 902)

LLLGDAFMSIQEPEKALEVYDEAYRKNPHDASLVSRIGQAYMKTHQYAKAINYYEAAQKI
S

ENSGT00390000005979_1_Linker_5_6 (902, 907)

GQDFL

PF13181 // ENSGT00390000005979_1_Domain_6 (907, 935)

CFDLAELLLKLKKYHKAEKVLKQ-ALER

ENSGT00390000005979_1_Linker_6_7 (935, 1022)

D--SGVKEIPSMMNEVKCLLLLA---
KVYRNHKK---EDVVETLNQALDLQSRILKRVPLEQPETIPFQKQLAASICIQM---GEH
Y

PF14559 // ENSGT00390000005979_1_Domain_7 (1022, 1088)

LTEKDYESAVKSYKDALSYSPT-DNTVALELAQLHLLLGQLDLCEQCCGPLLQTEQTHE
RAAVMLADLMFRKQNYETAINLYRQVLEKAPDNFLVLNKLIDLLRRSGKLE-EAPAFLEL
AKKVSSRVPLEPGFNFCQGIYFWHIGQPNEALRFLNKARKDSTWGQIATCYMVQICLNPD
DEIVGGEAFESLVTDS-SS-ASRRESQQHGVRTAEKLLREFYPHS-DSGQTQMRLLQSLC
LLATREKTNVEAALGAFIEMAQTERDSIPALLAMAQAYMLLKQVPKARTQLKRLAKVPWT
LSEAEDLE

PF13181 // ENSGT00390000005979_1_Domain_9 (1329, 1360)

KSWLLLADIYCQGGKFDLASELLRRCLQYNKSCCKAYEYMGFIMEKEQSYKD
AATNYELAWKYSYQA----SPAIGFKLAFNYL----KDKKFVDAIEVCHS----------
----------------------VLTEYPNYPKIREEILEKAQGSLRP

------------------------------------------------------------
MSSNDSCLMAGIIYYSQEKYFHHVQQTAAVGLEKFSNDPVLKFFKAYGVLKEEHIQDAIS
DLESIR-HYPDVSLCSTMALIYAHKRCE--IIDREAIQELEYSLKEIRKTVSGTALYYAG
VFLWLIGHHDKAKEYIDRMLKISRGFR----EAYVLRGWVDLTSDKPHTVKKAIEYLEQG
IQDTKDVLGLMGKAMYFMMQQNYSEALEVVNQITVTSGSFLPALVLKMQLFLARQDWEQT
VEMGHRILEKDESNIDACQILAVHELAREGNMTTVSSLKTQK----ATNHVRNLIKALET
REPENPSLHLKKILVV-SRLCGSHQVILGLVCSFIERSFIA-TPSYIHVATELGYFFILK
NQVKEALLWYTEAMKLDKDGMAGLTGIILCHILEGHLEEAEHQLEF-----LKEVQKSL-
---GKSEVLIFLQALLTSKKHKGEQETTALLKEAVELHFSSMQGLPLGSEYFEKLDPYFL
VCIAKEYLLFCPKQPRLPGQIVSPLLKQVAVILNPVVKAAPALIDPLYLMAQVRYYS-EL
ENAQSILQRCLELDPASVDAHLLMCQIYLAQGNFGMCFHCLELGVSHNFQVR--------
-------DHPLYHLIKARALNKAGDYPEAIKTLKMVIKLPALKKEEGRKF-LEPCLQTSQ
RASILLELVEALRLNGELHEATKVMQDTINEFGGTPEENRITIANVDLVLSKGNVDVALN
MLRNISPKQSCYMEAREKMANVYLQTLRDRRLYIRCY------RELCEH----LPGPHTS
L

PF13432 // ENSGT00390000005979_1_Domain_5 (842, 900)

LLGDALMSILEPEKALEVYDEAYRQNPHDASLASRIGQAYVKAHQYTEAIEYYEAAQKI
NGQDFLCCDLAELLLKLKKINKAGKVLKQ-ALEHD--I-VQDIPSMMNDVKCLLLLA---
KVYESHKK---EAVIETLNKALDLQSRILKRVPLEQPEMIPSQKQLAASICIQF---AEH
Y

PF14559 // ENSGT00390000005979_1_Domain_7 (1022, 1089)

LAEKEYDKAVRSYKDVFSYLPT-DNKVMLELAQLYLLQGHLDLCEQHCAILLQTEQNHE
TASVLMADLMFRKQKHEAAINLYHQVLEKVPDNFLVLNKLIDLLRRSGKLE-DIPAFFEL
AKKVSSRVPLEPGFNYCRGIYCWHIGQPNEALKFLNKARKDSTWGRSAIYHMVQICLNPD
NEVVGGEAFENQGAES-NY-TEKKELEQQGLSTAEKLLCEFYPNS-ASSQTQLRLLQGLC
RLATKEKANMEAALSSFIQIAQAEKDSVPALLALAQAYVFLKQIPKARMQLKRLAKAPWV
LSEAEDLEKSWLLLADIYCQGSKFDLALELLRRCVQYNKSCYKAYEYMGFIMEKEQSYKD
AVTNYKLAWKYSHHA----NPAIGFRLAFNYL----KDKKFVEAIEICHDV---------
-----------------------LREHPNYPKIREEILEKARRSLRP

------------------------------------------------------------
MSSNDSSLMAGIIYYSQEKYFHHVQQAAVAGLEKFSNDPVLHFFKAYGVLREERIQDAIS
DLESIR-NHPDTSLCSIMALLYAHKSCE--TIDREAIQELESSLKEIRRTAPETALYYAS
LFLWLMGYHDKAKEYIDHFLKVSHSSR----EGYVLKGWVELTSDKPHIVKKSIKYLEQG
IRDTKDVLGLMGKATYLMMQQNYSGALEVVNQITLASGNFLPALILKMRLFLARQDWEQA
IETGHRILEKDESNIDACQLLAVHELAREGNMTIA------------ADHVRNLIKVLEM
REPQNPSLHLKKIIVI-NRLCGNHRVILQLVSSFIERIFLA-SPSCAPVATELGYLFILQ
NQVKEAFLWYSEAMKLDENSMAALTGIIWCQILKGHLEEAEHQLEFLKEVQ---------
QSLGKSELLVFLQALLASKKHKGEQEATALLKEAVELHFSSMQGLPLGPEYLEQLDPLFL
VCIAKEYLHFCPKQPRAPGQILSPLLKQVTVILSPVVKAVPAMMEPLFVMAQVKYLSGEL
ENAQSVLQRCLELDPTSADTHLLMSQIHLAQGNFAMCSHSLELGVSHNFQVR--------
-------DHPLYHFIKARALNKSGDHPEAIKTLKMIMKLPTVKVEEGKKF-RGSPLPPRE
RVSILLELADALRLNGELHEATKVMQDAINEFSGTPEEIRITIANVDLALSKGNVDMALS
MLRNVTPKQPCYMEAKEKMASIYLHTRKDIRLYIGCY------RELCEH----LPGPHTS

PF13432 // ENSGT00390000005979_1_Domain_5 (841, 902)

LLLGDAFMNIQEPEKALEVYDEAYRKNPHDASLVSRIGQAYVKTHQYAKAINYYEAAQKI
S

ENSGT00390000005979_1_Linker_5_6 (902, 907)

GQDFL

PF13181 // ENSGT00390000005979_1_Domain_6 (907, 935)

CCDLAELLMKLKKFNKAEKVLKQ-ALGR

ENSGT00390000005979_1_Linker_6_7 (935, 1022)

D--F-AKDFPSMMNDVKCLLLLA---
KVYKNYKK---EDVVDTLNKALDLQSRILKRIPLEQPEMIPSQKQMAAFICIQF---GEH
Y

PF14559 // ENSGT00390000005979_1_Domain_7 (1022, 1082)

LAEKEYAKAVRSYKDALSYSPI-DNKVLLELAHLYLLQGHLDLCEQQCTTLLQTEKTQE
S

ENSGT00390000005979_1_Linker_7_8 (1082, 1085)

ASV

PF13432 // ENSGT00390000005979_1_Domain_8 (1085, 1143)

MMADLMFRKQKYEEAINLYQQVLEKAPDNFSVLNKLIDLLRRSGKLE-EAPAFFES
SK

ENSGT00390000005979_1_Linker_8_9 (1143, 1329)

RISSRVPLEPGFNYCKGIYSWHVGQPNEALKFLNKARKDSTWGPYATYYMVQICLNPD
NELVGGEAFENPMTES-NS-TNRKELEQHGVRTAEKLLREFYPHS-AFDQTQLRLLQSLC
LMATREKANVEVALGAFIEMAQAEKDNTPALLAMSQAYMLLKQIPKARTQLKRLAKVAWS
LAEAEDLE

PF13181 // ENSGT00390000005979_1_Domain_9 (1329, 1360)

KSWLLLADIYCQGGKYDLASELLRRCIQYNKSCCKAYEYMGFIMEKEQSYKD
AATNYELAWKYSHHA----NPTIGFKLAFNYL----KDKKFVEAIEVCHSVSHRRWQGGV
GSSQDPCLMLNT----YSLLVQVLMEHPNYPKIREEILGKAQGSLRI

------------------------------------------------------------
MSSNDSSLMAGIIYYSQEKYFHHVQQTAAVGLEKFSNDPVLKFFKAYGVLKEEHIQDAIS
DLESIR-HHPDVSLCSTMALIYAHKRCE--IIDREAIQELEYSLKEIRKTVSGTALYYAG
VFLWLIGHHDKAKEYIDRMLKISRGFR----EAYVLRGWVDLTSDKPHTAKKAIEYLEQG
IQDTKDVLGLMGKAMYFMMQQNYSEALEVVNQITVTSGSFLPALVLKMQLFLARQDWEQT
VEMAHRILEKDESNIDACQILAVHELAREGNMTTVSSLKTQK----ATNHVRNLIKALET
REPENPSLHLKKILVV-SRLCGSHQVILGLVCSFIERTFMA-TPSYIHVATELGYFFILK
NQVKEALLWYTEAMKLDKDGMAGLTGIILCHILEGHLEEAEHQLEF-----LKEVQKSL-
---GKSEVLIFLQALLTSKKHKGEQETTALLKEAVELHFSSMQGLPLGSEYFEKLDPYFL
VCIAKEYLLFCPKQPRLPGQIVSPLLKQVAVILNPVVKAAPALIDPLYLMAQVRY

PF14559 // ENSGT00390000005979_1_Domain_2 (596, 634)

YSGEL
ENAQSILQRCLELDPASVDAHLLMCQIYLAQGNFGMCFHCLELGVSHNFQVR--------
-------DHPLYHLIKARALNKAGDYPEAIKTLKMVIKLPALKKEEGRKF-LGPSLQTSQ
RASILLELVEALRLNGELHEATKVMQDTINEFGGTPEENRITIANVDLVLSKGNVDVALN
MLRNISPKQSCYMEAREKMANVYLQTLRDRRLYIRCY------RELCEH----LPGPHTS
L

PF13432 // ENSGT00390000005979_1_Domain_5 (842, 900)

LLGDALMSILEPEKALEVYDEAYRQNPHDASLASRIGQAYVKAHQYTEAIEYYEAAQK

ENSGT00390000005979_1_Linker_5_6 (900, 907)

I
NGQDFL

PF13181 // ENSGT00390000005979_1_Domain_6 (907, 933)

CCDLAELLLKLKKINKAEKVLKQ-AL

ENSGT00390000005979_1_Linker_6_7 (933, 1022)

EHD--I-VQDIPSMMNDVKCLLLLA---
KVYESHKK---EAVIETLNKALDLQSRILKRVPLEQPEMIPSQKQLAASICIQF---AEH
Y

PF14559 // ENSGT00390000005979_1_Domain_7 (1022, 1089)

LAEKEYDKAVRSYKDVFSYLPT-DNKVMLELAQLYLLQGHLDLCEQHCAILLQTEQNHE
TASVLMADLMFRKQKHEAAINLYHQVLEKVPDNFLVLNKLIDLLRRSGKLE-DIPAFFEL
AKKVSSRVPLEPGFNYCRGIYCWHIGQPNEALKFLNKARKDSTWGQSAIYHMVQICLNPD
NEVVGGEAFENQGAES-NY-TEKKELEQQGVSTAEKLLREFYPNS-ASSQTQLRLLQGLC
RLATKEKANMEAALGSFIQIAQAEKDSVPALLALAQAYVFLKQIPKARMQLKRLAKAPWV
LSEAEDLEKSWLLLADIYCQGSKFDLALELLRRCVQYNKSCYKAYEYMGFIMEKEQSYKD
AVTNYKLAWKYSHHDPHHDPRTQGFRLAFNYL----KDKKFVEAIEICHDV---------
-----------------------LREHPNYPKIREEILEKARRSLRP

------------------------------------------------------------
MNSNDSSLMAGIIYYSQEKYFHHVQQTAAVGLEKFSNDPVLKFFKAYGVLKEEHIQDAIS
DLESIR-HHPDVSLCSTMALIYAHKRCE--IIDREAIQELEYSLKEIRKTVSGTALYYAG
VFLWLIGHHDKAKEYIDRMLKISRGFR----EAYVLRGWVDLTSDKPHTAKKAIEYLEQG
IQDTKDVLGLMGKAMYFMMQQNYSEALEVVNQITVTSGSFLPALVLKMQLFLARQDWEQT
VEMGHRILEKDESNIDACQILAVHELAREGNMTTVSSLKTQK----ATNHVRNLIKALET
REPENPSLHLKKILVV-SRLCGSHQVILGLVCSFIERTFMA-TPSYIHVATELGYFFILK
NQVKEALLWYTEAMKLDKDGMAGLTGIILCHILEGHLEEAEHQLEF-----LKEVQKSL-
---GKSEVLIFLQALLTSKKHKGEQETTALLKEAVELHFSGMQGLPLGSEYFEKLDPYFL
VCIAKEYLLFCPKQPRLPGQIVSPLLKQVAVILNPVVKAAPALIDP

PF13181 // ENSGT00390000005979_1_Domain_2 (587, 616)

LYLMAQVRYYSGEL
ENAQSILQRCLELDPTSVDAHLLMCQTYLAQGNFGMCFHCLELGVSHNFQVR--------
-------DHPLYHLIKARALNKAGDYPEAIKTLKMVIKLPALKKEEGRKF-LGPSLQTSQ
RASILLELVEALRLNGELHEATKVMQDTINEFGGTPEENRITIANVDLVLSKGNVDVALN
MLRNISPKQSCYMEAREKMANVYLQTLRDRRLYIRCY------RELCEH----LPGPHTS
L

PF13432 // ENSGT00390000005979_1_Domain_5 (842, 900)

LLGDALMSILEPEKALEVYDEAYRQNPHDASLASRIGQAYVKANQYTEAVEYYEAAQK

ENSGT00390000005979_1_Linker_5_6 (900, 907)

I
NGQDFL

PF13181 // ENSGT00390000005979_1_Domain_6 (907, 933)

CCDLAELLLKLKKINKAEKVLKQ-AL

ENSGT00390000005979_1_Linker_6_7 (933, 1022)

EHD--I-VQDIPSMMNDVKCLLLLA---
KVYESHKK---EAVIETLNKALDLQSRILKRVPLEQPEMIPSQKQLAASICIQF---AEH
Y

PF14559 // ENSGT00390000005979_1_Domain_7 (1022, 1089)

LAEKEYDKAVRSYKDVFSYLPT-DNKVMLELAQLYLLQGHLDLCEQHCAILLQTEQNHE
TASVLMADLMFRKQKHEAAINLYHQVLEKVPDNFLVLNKLIDLLRRSGKLE-DIPAFFEL
AKKVSSRVPLEPGFNYCRGIYCWHIGQPSEALKFLNKARKDSTWGQSAIYHMVQICLNPD
NEVVGGEAFENQGAES-NY-TEKKEVEQQGVSTAEKLLREFYPNS-ASSQTQLRLLQGLC
RLATKEKANMEAALGSFIQIAQAEKDSVPALLALAQAYVFLKQIPKARMQLKRLAKAPWV
LSEAEDLEKSWLLLADIYCQGSKFDLALELLRRCVQYNKSCYKAYEYMGFIMEKEQSYKD
AVTNYKLAWKYSHHA----NPAIGFRLAFNYL----KDKKFVEAIEICHDV---------
-----------------------LREHPNYPKIREEILEKARRSLRP

------------------------------------------------------------
MSSDDSSLMASIIYYSQEKYFHHVLQAANVGLERYSSDPALQFFRAYGILGEDHIHDAIS
ELEGIQ-SHPDTSLCAVIALLSAHKSCD--TIDIEAVQELESSLKEIRRSASSTALYYAS
LFLWFMGHHDKAREYVDHMLKVSSGSK----EGYVLKGWVDLTSSKPHVVKKSIKYLEQG
TQDTKDVLGLMGKATYFMTQQNFSGALEVANQVTLACSNFLPALVLKMKLFLARQDWDQT
IETGQRILEKDENNIDAWQILAVHELVKEGNTDRA------------ADRVRNLIKALET
GEPHNPNLHLKKILVI-SRLCGRHQVVHRLVSGFLERIFMA-TPSCALVATELGYLFILH
QQVKEACLWYKEAMKLEENRLAALAGSIWCQILQGQLEEAAHQLEFLKEVQ---------
QSLGKSELLVFLQALVAAKKQRLEQEATALLKEAVEVHFSSMQGLALSPEYFEKLDPLFL
VCIAKEYLHFCPKQPRSPGQLVSPLLKQVAMILSPVVKVAPAMMEPLYVTAQVKFLSGEL
ENAQSTLQRCLELDPTFVDAHLLMSQIYLAQGNFAMCSHCLELGVSHNFQVR--------
-------DHPLYHFIKARALNKTGDYAEAIKTLKMIIKVPTSKAEEGRKS-QSPSVRPSE
RASILLELVEALRLNGELHEATKIMQDAINEFSGTPEEMRITVANVDLALSKGNVDLALN
MLRGITPKQPCYTEAKEKMASIYLHTRKDVRLYIGCY------VELCEH----LPGPHSS

PF13432 // ENSGT00390000005979_1_Domain_5 (841, 902)

LLLGDAFMNIQEPEKALEVYDEAYRKNPHDASLVSRIGQAYVKTHQYAKAINYYEAAQKI
S

ENSGT00390000005979_1_Linker_5_6 (902, 907)

GQDFL

PF13181 // ENSGT00390000005979_1_Domain_6 (907, 935)

CCELAELLLKLKKYHKAEKVLKQ-ALER

ENSGT00390000005979_1_Linker_6_7 (935, 1022)

D--SGVKDIPSMINEVKCLLLLA---
KVYKSHKK---EEVMETLNLALDLQSRILKRVPLEQSEMIPFQNQLAASICIQI---GEH
H

PF14559 // ENSGT00390000005979_1_Domain_7 (1022, 1088)

LAEKDYDSALKSYKDALAYSPT-DSKVVLELAHLYLLLGQLDLCEQRCAPLLEMEQTHE
RAAVMLADLMFRRQNYETAINLYHQVLEKAPDNFLVLNKLVDLLRRSGKLE-EAPAFFEL
AKKVSSRVPLEPGFNYCQGIYFWHIGQPNEALRFLNKARKDSTWGQLATCYMVQICLNPD
NEIVGGEAFESLVGDS-NS-ASRKESQQHGVRTAEKLLREFYPHS-ESGQTQLRLLQNLC
LLATREKANVEVALGAFIEMAQAEKDSIPALLAMAQAYILLKQVPKARTQLKRLAKVPWT
VDEAEDLEK

PF13176 // ENSGT00390000005979_1_Domain_9 (1330, 1355)

SWLLLADIYCQGGKFDLALELLRRCLQYNKSCCRAYEYMGFIMEKEQSYKD
AATNYELAWKYSHQA----NPAIGFKLAFNYL----KDKKFVDAIEVCHS----------
----------------------VLTEHPKYPKIREEILEKAQGSLRP

------------------------------------------------------------
MSSNDSSLMAGIIYYSQEKYFHHVQQTAAVGLEKFSNDPVLKFFKAYGVLKEEHIQDAIS
DLESIR-HHPDVSLCSTMALIYAHKRCE--IIDREAIQELEYSLKEIRKTVSGTALYYAG
VFLWLIGHHDKAKEYIDRMLKISRGFR----EAYVLRGWVDLTSDKPHTAKKAIEYLEQG
IQDTKDVLGLMGKAMYFMMQQNYSEALEVVNQITVTSGSFLPALVLKMQLFLARQDWEQT
VEMGHRILEKDESNIDACQILAVHELAREGNMTTVSSLKTQK----ATNHVRNLIKALET
REPENPSLHLKKILVV-SRLCGSHQVILGLVCSFIERTFMA-TPSYIHVATELGYFFILK
NQVKEALLWYTEAMKLDKDGMAGLTGIILCHILEGHLEEAEHQLEF-----LKEVQKSL-
---GKSEVLIFLQALLTSKKHKGEQETTALLKEAVELHFSSMQGLPLGSEYFEKLDPYFL
VCIAKEYLLFCPKQPRLPGQIVSPLLKQVAVILNPVVKAAPALIDPLYLMAQVRY

PF14559 // ENSGT00390000005979_1_Domain_2 (596, 634)

YSGEL
ENAQSILQRCLELDPASVDAHLLMCQIYLAQGNFGMCFHCLELGVSHNFQVR--------
-------DHPLYHLIKARALNKAGDYPEAIKTLKMVIKLPALKKEEGRKF-LGPSLQTSQ
RASILLELVEALRLNGELHEATKVMQDTINEFGGTPEENRITIANVDLVLSKGNVDVALN
MLRNISPKQSCYMEAREKMANVYLQTLRDRRLYIRCY------RELCEH----LPGPHTS
L

PF13432 // ENSGT00390000005979_1_Domain_5 (842, 900)

LLGDALMSILEPEKALEVYDEAYRQNPHDASLASRIGQAYVKAHQYTEAIEYYEAAQK

ENSGT00390000005979_1_Linker_5_6 (900, 907)

I
NGQDFL

PF13181 // ENSGT00390000005979_1_Domain_6 (907, 933)

CCDLAELLLKLKKINKAEKVLKQ-AL

ENSGT00390000005979_1_Linker_6_7 (933, 1022)

EHD--I-VQDIPSMMNDVKCLLLLA---
KVYESHKK---EAVIETLNKALDLQSRILKRVPLEQPEMIPSQKQLAASICIQF---AEH
Y

PF14559 // ENSGT00390000005979_1_Domain_7 (1022, 1089)

LAEKEYDKAVRSYKDVFSYLPT-DNKVMLELAQLYLLQGHLDLCEQHCAILLQTEQNHE
TASVLMADLMFRKQKHEAAINLYHQVLEKVPDNFLVLNKLIDLLRRSGKLE-DIPAFFEL
AKKVSSRVPLEPGFNYCRGIYCWHIGQPNEALKFLNKARKDSTWGQSAIYHMVQICLNPD
NEVVGGEAFENQGAES-NY-TEKKELEQQGVSTAEKLLREFYPNS-ASSQTQLRLLQGLC
RLATKEKANMEAALGSFIQIAQAEKDSVPALLALAQAYVFLKQIPKARMQLKRLAKAPWV
LSEAEDLEKSWLLLADIYCQGSKFDLALELLRRCVQYNKSCYKAYEYMGFIMEKEQSYKD
AVTNYKLAWKYSHHDPHHDPRTQGFRLAFNYL----KDKKFVEAIEICHDV---------
-----------------------LREHPNYPKIREEILEKARRSLRP

------------------------------------------------------------
MSSNDSALMAEIIYYSQEKYFRHVQQVASLGLEKFSNDPVLLFFRAYGILREERIQDAIS
ELESIQ-RHPDVSLCAIMALIYAHKCCE--TVDREAVLELESSLKGIRKKASNTALYYAS
LFLWLVGRPDKAREYVDHMLKTCGSSR----EGCVLKGWVDLTSNKAHVVKKSIKYLEQG
TQDPKDMLGLMGKATYFLMQQNFSMALEVVSQVTAACGHFLPAFVLKMRLFLAQQDWEQT
LETGHRILELDEGNIDAWQVLAVHELVREGSMAAA------------ADHVRNLIKALET
REPHNADLHFRRILVV-GRLCGRHHAVMRLVSTFMERIFMA-MPSCSLVATELGYHFMLQ
HQVKEASLWYSKAMKLEDNKMAALAGSIWCQILQGQLDEASHQLEFLKEVQ---------
QSLGKFEVLVFLQALVASRRHRGELEVTALLKEAVELHFSGMQGLPLSPEYFEKLDPLFV
VCLAKEYLHFCPKQPRSPGQLVSPLLKQVAMILSPVVKAAPAMMDP

PF13181 // ENSGT00390000005979_1_Domain_2 (587, 616)

LYVMAQVKYLSGEL
ENAQSALQRCLELDPTFVDAHLLMSQIYLAQGNFAMCSHCLELGVSHNFQVR--------
-------DHPLYHFIKARALNKTGDYPEAIKTLKMIIKLPTVKVEEGRKL-RGPYVKPSE
RASILLELVEALRLNGELHEATKIMQDAINEFSGTPEEMRVTIANVDLALSKGNVDLALS
TLRGISPKQACYTEAKEKMASIYLHSRKDAHLYIGCY------LELCEH----VPGPHSS

PF13432 // ENSGT00390000005979_1_Domain_5 (841, 902)

LLLGDAFMNIQEPEKALEVYDEAYRKNPHDATLVSRIGQAYVKTHQYTKAINYYEAAQKI
S

ENSGT00390000005979_1_Linker_5_6 (902, 907)

GQDFL

PF13181 // ENSGT00390000005979_1_Domain_6 (907, 938)

CCDLAELLLKLKKFHKAEKVLKQ-ALERD--SATKDILSMMNEVKCLLLLA---
KVYKSHKR---EDVMETLNKALDLQSRILKRVPLEQPETIPFQKQLAASICIQF---GEH
FQAEKDYGKAAQYYKDALSYSPT-DNKVVLELARLSLLQGHLDLCEQHCGTLLQMEETHE
SAIV

PF13432 // ENSGT00390000005979_1_Domain_8 (1085, 1143)

MMADLMFRKQDYEAAISYYRHVLEKAPDNFSVLNKLIDLLRRVGEID-EAPAFFEL
AK

ENSGT00390000005979_1_Linker_8_9 (1143, 1329)

KVSSRVPLEPGFNYCRGIYCWHIGQPSEALKFLNKARKDSTWGQSATSYMVQICLNPD
NEVVGGEAFESLSADS-HP-TSRKESQQRGVHTAEELLQESYLRSTSSDQRQLQMLQSLC
LLATREKANMEMALGTFIEMAQAEKDNVPAILAMAQAYMLLKQTPKARTQLKRLAKAPWT
LAEAEDLE

PF13181 // ENSGT00390000005979_1_Domain_9 (1329, 1360)

KSWLLLADIYCQSGKFDLACELLRRCLQYNKSCCKAYEYMGFIMEKEQSYKD
AATNYELAWKYSHQA----NPAIGFKLAFNYL----KDKKFVDAIEVCHN----------
----------------------VLTEHPNYPKIREEILEKAQGSLRP

------------------------------------------------------------
MCSSDSSLLAGIIYYSQEKYFRHVQQAAAVGLQKFSNDPVLQFFKSYGVLREERVQDAIS
ELENIR-GHPDLSLCSVMALLYAHKCCE--IVDREAIQELETSLKEVREQASETALYYAG
LFLWLIGRHDKAREYVDHMLNASSSFR----EGYVLKGWVDLTSEKPHIVKKSIKYLEQG
MQSNKDVLGLMGKATYLMIQQNYSGALDVVNQISTASGSFLPALVLKMRLFLAQQDWEQT
METTHRILEKDESNIDACQILTVHELVREGNMTTA------------TDNVRNLIKALEM
REPQNPSLQLKKILVI-SRLCGRHRAILRLVSSFMERIFLA-MPSCAQVATELGYLFILQ
NQEKEAALWYSEAMKLGENSVAALTGTIWCHILKDELEEAEHQLEFLKEVQ---------
QSLGRSEVLVFLQALLASKKHKGEQEVTALLQEVVELHFSHLQGLPLSPEYLEKLDPPFL
VCIAKEYLQFCPKQPRAPGQLVSPLLKQAAVILSPVVRAAPALPDPLYVMGQVKYLSGEL
ENAQST

PF13431 // ENSGT00390000005979_1_Domain_2 (607, 637)

IQRCLELDPTSADAHLLLAQIYLAQGNFAMCSHCLELGVSHNFQVR--------
-------DHPLYHFIKARALSKSGDYQEAIKTLKMIMKLPTLKTEESRKI-RGPSVQPSE
RVSILLELVDALRLNGELHEATKVMQDTINEFSGTAEEIRITIANVDLALSKGNMDLALS
MLRNITPKQPCYTEAKEKMASIYLHSRKDTCLYIGCY------RELCEH----LPGPHTS

PF13432 // ENSGT00390000005979_1_Domain_5 (841, 900)

LLLGDAFMNIQEPEKALEVYNEAYKKNPHDASLVSRIGQAYVKTHQYSKAINYYEAAQK

ENSGT00390000005979_1_Linker_5_6 (900, 907)

I
SGLDFL

PF13181 // ENSGT00390000005979_1_Domain_6 (907, 932)

CCDLAELLLKLKKFNKAEKVLKQ-A

ENSGT00390000005979_1_Linker_6_7 (932, 1008)

LGHD--VAVKDIPSMMNDVKCLLLLA---
KVYKSYKK---EEVLETLNKALNLQSRILKRVPLEQPEMLPSQKQLA

PF13181 // ENSGT00390000005979_1_Domain_7 (1008, 1043)

ASICMLF---GEF
YSAEKDYAKAVQSYRDALSYSP

ENSGT00390000005979_1_Linker_7_8 (1043, 1084)

T-DNKVVLELAHLSLLQGYLDLSEQHCVILLQTDQAHE
TAS

PF13432 // ENSGT00390000005979_1_Domain_8 (1084, 1141)

LMMADLMFRKQNYEAAINLYHQVLEKAPDNFSVLDKLIDLLRRSGKLD-EAPAFFQL

ENSGT00390000005979_1_Linker_8_9 (1141, 1329)

VKKMSSRVSMEPGFNYCRGIYCWHIGQPNQALKFLNKARKDITWGQRANYYMVHICLNPD
NEIMGGEAFENQLTNT-NS-TARKESEQQGVRTAEKLLRDFYPLS-VIGQTQQRLLQSLC
LLATREKANMEAALGAFLEIAQAEKDSIPALLGVSQACMLLKQVPKARTQLKRLAKVPWT
LVEAEDLE

PF13181 // ENSGT00390000005979_1_Domain_9 (1329, 1360)

RSWLLLADIYSSGGKFDLASELLRRCIQYNKSCYKAYEYMGFIMEKEQSYKD
AATNYELAWKYSHQA----NPAIGFRLAFNYL----KDKKFVQAIEVCHN----------
----------------------VLREHPSYPKIREEILEKARRSLKP

------------------------------------------------------------
--------------YSQEKYFRHVQRAAAVGLEKFSNDPVLQFFKAYGVLREERIQDAIN
ELENVR-GHPDLSLCSIIALLYAHRRCE--TLDREAIQELESELKEVHRLASETALYYAG
LFLWLIGRHDKAKEYVDHMLKVSSSSR----EGCVLKGWVDLTSEKPHLVKKSIKYLEQG
IQINKDVLGLMGKATYLMMQQNYSGALDTVNQISLASGSFLPALILKMQLFLAQQDWEQM
IETVHRILEKDDSNIDACQILAVHQLMREGNCPFS------------DVALL--------
-SPAGLTFPIPSLPHACSLQCGRHRAILQLVSNFMERIFLA-VPSCAQVATELGYLFILQ
NQEKEAALWYSKAMKLGENSMAALAGTIWCHILKDELEEAEHQLEFLKEVQ---------
QSLGRSEVLVFLQALLASKKHKGEQEVTALLQEAAELHFSNVQGLPLSPQYLEKLDPPFL
VCIAKEYLQFCPKQPRAPGQLVSPLLKQAALILSPVVKAAPALIDPLYVMGQVQYLSGEL
ENAQSTVQRCLELDPTSTDAHLLMAQIYLVQGNFAMCSHCLELGVSHNFQVR--------
-------DHPLYHLIKARALNKSGDYQEAIKTLKMIMKLPTLKAEEGRKT-RRPFVQPSE
RVSILLELVSALRLNGELHEATKVMQDAIIEFSGTTEEISITIANVDLALSKGNVDLALS
MLKDITSKQPCYMEAKEKMASIYLQNRKDTYLYIGCY------RELCEH----LPGPHTS

PF13432 // ENSGT00390000005979_1_Domain_5 (841, 904)

LLLGDAFMRIQEPEKALEVYNEAYKKNPHDASLVSRIGQAYVRTHQYSKAINYYEAAQKI
SGQ

ENSGT00390000005979_1_Linker_5_6 (904, 906)

DS

PF13181 // ENSGT00390000005979_1_Domain_6 (906, 933)

LCCDLAELLLKLKKFNKAEKVLKQ-ALEHD--F-VKDIPSMMNDVKCLLLLA---
KVYKSYKR---EEVSETLNKALNLQSRILKRVPLEQPEMLPSQKQLAASICMLF---GEF
YWAEKDYARSLATV--------S-SLQVVLELARLSLLQGYLDSCEQHCTVLLQTDQTHE
SASV-M

PF13432 // ENSGT00390000005979_1_Domain_8 (1087, 1145)

ADLMFRKQNYDAAFNLYHQVLEKAPDNFLVLDKLIDLLRRSGTLE-EAPAFFQS
AQKMSSRVPMEPGFNYCRGIYCWHIGQPNQALKFLNKARKDITWGQKANYYMVHICLNPD
NELVGGEAQG--------S-ATRKESEQQGIRTAEKLLRDFYPLS-ASGQTQLRLLQSLC
LLTTREKANVEAALGAFLEIAQAEKDSVPALLGMAQACVLLKQIPKARTQLKRLAKAPWT
LAEAEDLEKSWLLLADIYCSGGKFDLATELLRHCIQYNKSCYKAYEYMGFIMEKEQSYKD
AATSYELAWKYSHQA----NPAIGFRLAFNYL----KAKKFVEAIEVCHN----------
----------------------VLREHPSYPKIREEILEKAQKSLRP

------------------------------------------------------------
MSSSDSSLLAGIIYYSQEKYFRHVQQAAAVGLEKFSNDPVLQFFKAYGLLREERVQDAIS
ELENIR-GHPDLSLCSIMALLYAHRHCE--TIDREAIQELESSLKEVRKLASETALYYAS
LFLWLIGRYDKAKEYVDHMLKVSSSSR----EGYVLKGWVDLTSEKPHLVKKSIKYLEQG
IQSNKDALGLMGKATYLMMQQNYSGALDAVNQISTASGSFLPALVLKMRLFLAQQDWEQM
IETAYRILEKDDSNIDACQMLVVHELVREGNMTTA------------TDHVRNLIKALEM
REPQNPNLQLKKVLVV-SRLCGRHRAILRLVSSFVERIFLA-MPSCAQVATELGYLYILQ
NQEKEAALWYLEATKLGENSMAALTGTIWCHILRDELEEAEHQLEFLKEVQ---------
QSLGRSEVLVFLQALLASKKHKGEQEVTALLREAAELHFSSIQGLPLGPEYLEKLDPPFL
VCIAKEYLQFCPKQPRAPGQLVSPLLKQAAVILSPVVKAAPALMEPLYVMGQVKYLSGEL
ENAQSTVQRCLELDPTSTDAHLLMAQIYLAQGNFAMCSHCLELGVSHNFQVR--------
-------DHPLYHLIKARALNKSGDYQEAIKTLKMIMKLPTLKAEESRKT-RSPSMQPSE
RVSILLELVDALRLNGELHEATKVMQDAINEFSGTAEEICITIANVDLALSKGNVDLALS
MLRDITPKQPCYTEAKEKMASIYLQSRKDTYLYIGCY------RELCEH----LPGPHTS

PF13432 // ENSGT00390000005979_1_Domain_5 (841, 901)

LLLGDAFMNIQEPEKALEVYDEAYKKNPHDASLVSRIGQAYVKTHQYSKAINYYEAAQKI

ENSGT00390000005979_1_Linker_5_6 (901, 907)

SGQDFL

PF13181 // ENSGT00390000005979_1_Domain_6 (907, 935)

CCDLAELLLKLKKFNKAEKVLKQ-ALER

ENSGT00390000005979_1_Linker_6_7 (935, 1022)

D--F-VKDIPSMMNDVKCLLLLA---
KVYKSYKK---EEVLETLNKALNLQSRILKRVPLEQPEMLPSQKQLAASICMLF---GEF
Y

PF14559 // ENSGT00390000005979_1_Domain_7 (1022, 1087)

LAEKNYARAVQSYKDALSYSPT-DNKVVLELAHLSLLQGHLDLCEQHLAVLLQTDQTHE
TASVMMADLMFRKQNYESAINLYHQVLEKAPDNFLVLDKLIDLLRRSGKLD-EAPTFFQL
AKKMSSRVPMEPGFNYCRGIYCWHVGQPNQALKFLNKARKDITWGQKANYYMVHICLNPD
NEIMGGEAFENQLTKS------KKESEQQGIRTAEKLLRDFYPLS-AFGQTQLRLLQSLC
LLATREKANVEAALGAFLEIAQAEKDSVPALLGMAQACVLLKQIPKARTQLKRLAKAPWT
LAEAEDLE

PF13181 // ENSGT00390000005979_1_Domain_9 (1329, 1360)

KSWLLLADIYSSGGKFDLASELLRRCIQYNKSCYKAYEYMGFIMEKEQSYKD
AATNYELAWKYSHQA----NPAIGFKLAFNYL----KDKKFVEAIEVCHK----------
----------------------VLREHPSYPKIREEILEKARRSLRP

-----------------------------------------------------------M
NSSDSSSLLARIIYYSQEKYFRHVQQAATMGLEKFSNDPVLQFFKTYGILREERVQDAIS
ELENIR-GHPDLSLCSIMALLYAHKHCE--TIDREAIQELESSLKETRKLASETALYYAG
LFLWLVGRHDKAKEYVDHMLKISSSSR----EGYVLKGWVDLTSEKPHLVKKSIKYLEQG
IQSNKDALGLMGKATYLMMQQNYTGALDVVNQISTASGSFLPALILKMRLFLAQQDWEQM
TETACRILEKDDSNIDACQTLAIHELVREGNMTTA------------TEHVSNLIKALEM
REPQNPSLQLKKVLVV-SRLCGRHRAILRLVSSFMERIFLA-MPSCAKVATELGYLFVLQ
NQEKEAALWYSEATKLGENSMAALTGTIWCHILKDELEEAEHQLEFLKEVQ---------
QSLGKSEVLVFLQALLASKKHKGEQEVTALLREAVELHFSSVQGLPLGPEYLEKLDPPFL
VCIAKEYLHFCPKQPRAPGQLVSPLLKQVSVILSPVVKAAPALMDP

PF13181 // ENSGT00390000005979_1_Domain_2 (587, 616)

LYMMGQVKYLSGEL
ENAQSIVQRCLELDPTSTDAHLLMAQIYLAQGNFAMCSHCLELGVSHNFQVR--------
-------DHPLYHLIKARALNKSGDYKEAIKTLKMIVKLPTLKAEESRKT-RSPSVQPSE
RVSILLELVDALRLNGELHEATKVMQDAINEFSGTAEEICITIANVDLALSKGNVDLALS
MLRDITPKQPCYMEAKEKMASIYLQIRKDTYLYIGCY------RELCEH----LPGPHTS

PF13432 // ENSGT00390000005979_1_Domain_5 (841, 902)

LLLGDAFMNIQEPEKALEVYDKAYKKNPHDASLVSRIGQAYVKTHQYSKAINYYEAAQKI
S

ENSGT00390000005979_1_Linker_5_6 (902, 907)

GQDFL

PF13181 // ENSGT00390000005979_1_Domain_6 (907, 933)

CCDLAELLLKLKKFNKAEKVLKQ-AL

ENSGT00390000005979_1_Linker_6_7 (933, 1022)

EHD--F-VKDIPSMINDVKCLLLLA---
KVYKSYKK---EEVVETLNKALNLQSRILKRIPLEQPEMLPSQKQLAASICMLF---GGF
Y

PF14559 // ENSGT00390000005979_1_Domain_7 (1022, 1089)

LAEKDYAKAAQSYKDALSYSPT-DNKVLLELAHLSLLQGYLDLCEQHCAVVLQTDQTHE
TASMMMADLMFRKQNYEAAINLYRQILEKAPDNFLVLDKLIDLLRRSGKLD-EAPAFIQT
SAKMSSRVSMEPGFNYCSGIYCWHVGQPNQALQFLNKARKDITWGQKANYCMVHICLNPD
NEVVGGEAFENHPGFA------TRKESEQGIRTAEKLLRDFYPLS-AFGQTQLRLLQSLC
LLATREKANVEAALGTFFEIAQAEKDSIPALLGIAQACMLLKQIPKARTQLKRLAKAPWT
LAEAEDLE

PF13181 // ENSGT00390000005979_1_Domain_9 (1329, 1360)

KSWLLLADIYSSGGKFDLASELLRRCIQYNKSCYKAYEYMGFIMEKEQSYKD
AATNYELAWKYSSRA----NPAIGFKLAFNYL----KDKKFVEAIEVCHK----------
----------------------VLREQPSYPKIREEILEKAQRSLRP

------------------------------------------------------------
MSGNDSSLMAGIIYYSQEQYFRHVQQAAALGLEKFSNDPVLQFFKTYGILREEHIQDAIS
NLESIR-NHPDVSLCSIMALIYAHKCCE--TIDQEAIQELESSLKEVRKIAS

PF07719 // ENSGT00390000005979_1_Domain_0 (173, 206)

ATALYYAG
LFLWLMGRHNKAREYIDRTLKISSS

ENSGT00390000005979_1_Linker_0_1 (206, 407)

SR----EGYVLRGWVDLTSDKPHTVKKSIKYLEQG
VQDSKDVLGLMGKATYFMLQQNYSGALEVVNQITVASGNFLPALVLKMRLFLARQDWEQT
VETGHRILEKDDCNIDAYQILAVHELAREGNMTTVSSFKMQE----AASHVRNLIKALET
REPQNPSLHLKKILVV-SRLCGKHQVILRLVCGFIERTFMA-TPSY

PF00515 // ENSGT00390000005979_1_Domain_1 (407, 440)

AHVATQLGYLFILQ
DQVREASLWYSEAMKLDES

ENSGT00390000005979_1_Linker_1_2 (440, 584)

SVAALTGVIWCQILDGHLEEAEHQLEFLKEVQ---------
QSLGKSQVLVFLQALLASRKHKGEQEATALLKEATELHFSSMQGLPLGSEYFEKLDPLFL
VCLAKEYLFFCPKQPRSPGQIVSPLLKQVAVILNPVVKAAPAL

PF00515 // ENSGT00390000005979_1_Domain_2 (584, 617)

IDPLYVMAQVKYLSGEL
ENAQSTLQRCLELDPT

ENSGT00390000005979_1_Linker_2_3 (617, 670)

SVDAHLLMSHIYLAQGNFAMCSHCLELGVSHNFQVR--------
-------DH

PF00515 // ENSGT00390000005979_1_Domain_3 (670, 699)

PLYHYIKARALNKSGDYPEAIKTLKMIVK

ENSGT00390000005979_1_Linker_3_4 (699, 837)

LPTRKVEEGKKF-RGPSVQPSE
RVSILLELADALRMNGELHEATKVMQDAINEFSGTPEEIRITIANVDLALSKGNVDMALS
MLRNITPKQPCYTEAKEKMANIYLQTRKDTRLYIGCY------RELCEH----LPG

PF00515 // ENSGT00390000005979_1_Domain_4 (837, 870)

PHTS
LLLGDAFMNIQEPEKALEVYDEAYRKNPHDASLVSRIGQAYVKTHQYTKAINYYEAAQKI
SGQDFL

PF00515 // ENSGT00390000005979_1_Domain_6 (907, 935)

CCDLAELLLKLKKFNKAEKVLKQ-ALEHD--S-VRDVPSMMNDVKCLLLLA---
KVYKSHKK---EDVMGTLDKAMDLQSRILKRIPLEQPEIIPSQKQLAASICVQF---GEH
YLAEKEFAKAVRSYKDALFYLPV-DNKVVLELARLYLLQGQLDLCEQHCASLLQSEQNH

PF00515 // ENSGT00390000005979_1_Domain_8 (1080, 1113)

E
TASVMMADLMFRKQKYEAAVNLYHQVLEKAPDNFLVLNKLIDLLRRSGRLE-DAPAFFEL
TKRMSSRVPLEPGFNYCRGIYCWHIGQPNEALKFLNKARKDSTWGQSATYYMVQICLNPD
NEIVGGQVFENLVADS-NC-THRKDSEQHGVRTAEKLLREFYPPS-AWGQTQLRLLQSLC
LLATREKANVEAALGTFIEMAQAEKDSVPALLAMAQAYALLKQVPKARTQLKRLAKAPWA
LGEAEDL

PF00515 // ENSGT00390000005979_1_Domain_9 (1328, 1361)

EKSWLLLADLYCQGGKFDLAWELLRRCIQYNQS

ENSGT00390000005979_1_Linker_9_10 (1361, 1401)

CCKAYEYMGFIMEKEQSYKD
AATNYELAWKYSHRA----N

PF00515 // ENSGT00390000005979_1_Domain_10 (1401, 1470)

PAIGFKLAFNYL----KDKRFVEAIEVCHN----------
----------------------VLREHPNYPQIREEILEKAQGSLRP

------------------------------------------------------------
---MSSSPQAEIIYYSQEQYFRHVQRAAALGLEKFSNDPVLQFFKTYGILREEHIQDAIS
NLESIR-NHPDVSLCSIMALIYAHKRCE--TIDQEAIQELESSLKEIRKTASTTALYYAG
LFLWLIGHYDKAREYIDCNLKLSNNSR----EGLVLRGWVDLTSDKSHIMKKSTKFLEQG
IQDAKDVLGLMGKATYLMMQQNYSGALEVVNQITVTSGSFLPALILKMQLFLARQDWEQT
VEMGHRILEKDDGNIDACQILAMHELAREGNMTTA------------ANHVRNLIKALET
REPRNPSLHLKKILVV-SRLCGRNQAVLQLVCSFIERIFMA-TSSYAHVATELGYLFILQ
DQVKEASLWYSEAMKLDANSVAALTGVTWCQILEGHLEEAQQQLEFLKEVQ---------
QSLGKSEVLVFLQALLASRKHKEGQKATALLKEAAELHFSSMQGLPLGCEYFEKLDPLFL
VCIAKEYLFFCPKQPRSPGQIVSQLLKQVTVILNPVVKAAPALIDPLYVMAQVKYLSGEL
ENAQSTLQRCLELDPTYVDAHLLMSHIYLAQGNFAMCSHCLELGVSHNFQVR--------
-------DHPMYHFIKAKALNKSGDHPEAIKTLKMIIKLPTRKMEEGKKF-RGPSVRPSE
RVSILLELVDALRMNGELHEATKVMQDAINEFSGTPEEIRITIANVDLALSKGNVDMALS
MLRNITPKQPWYTEAKEKMANIYLQTRKDTRLYISCY------RELCEH----LPGPHTS
L

PF13414 // ENSGT00390000005979_1_Domain_5 (842, 901)

LLGDAFMNIQEPEKALEVYDEAYRKNPHDASLVSRIGQAYVKTHQYAKAINYYEAAQKI

ENSGT00390000005979_1_Linker_5_6 (901, 907)

SGQDFL

PF00515 // ENSGT00390000005979_1_Domain_6 (907, 935)

CCSLAELLLKLKKFNKAEKVLKQ-ALEH

ENSGT00390000005979_1_Linker_6_7 (935, 1021)

D--S-VKDIPSMMNDVKYLLLLA---
KVYKSHKK---EDVMETLNKAMDLQSRILKRVPLEQPEMIPSQKQLAASICVQF---GEH

PF14559 // ENSGT00390000005979_1_Domain_7 (1021, 1087)

YLAEKQFAKAARSYKDALVYSPI-DNKVVLELAKLYMLQGHLDLCEQHCAVILQTEKNHE
SASVMM

ENSGT00390000005979_1_Linker_7_8 (1087, 1091)

AELM

PF00515 // ENSGT00390000005979_1_Domain_8 (1091, 1113)

FRKQKYEDAINLYQQVLEKAPDNFLVLNKLIDLLWRSGRLE-DAPAFFEL
AKRVSSRVPLEPGFNYCRGIYCWHIGQPNDALKFLNKARKDSTWGQSATYYMVQICLNPD
NEVVGGEVFENLVAES-NGSTDRRDAEQQGVRTAEKLLRESYPHS-AAGQTQLRLKESLC
LLATRTGLCPAMGFSPV-------------------------------------------
------------------CGTGP------------------AAFFMTHGRGVEKEQSYKD
AATNYELAWKYSHHA----NPAIGFKLAFNYL----KDKRFVDAIEVCHN----------
----------------------VLREHPNYPKIREEILEKARGSLRP

------------------------------------------------------------
---------ALIIYYSQEKCFRHVQQAASMGLERYSNDPVLQFFKAYGVLGEDHIHDAIS
ELESLQ-SHPHMSLCSVMALLYAHKCCD--TIDAEAVQELESSLKEIRKTASDTALYYAS
LFLWLTGHHDKAREYVDHMLKVCNGSK----EGYVLKGWVDLTSSKPHVVKKSIKYLEQG
TQDTKDTLGLMGKATYFMTQQNFSGALEVVNQVTVASGNFLPALVLKMRLFLARQDWDQT
IETAHRILEKDESNIDAWQTLTVHELVREGNTATA------------TDHVRSLIKALET
GEPQNPSLHLKKIVVV-SRLCGRHQAVQRLVSGFLERIFMA-TPSCAAVATELGYLFILQ
QQVKEASLWYKEAMKLEENRLSALAGSIWCQILQGQLDEAAHQLEFLREVQ---------
QSLGKSEVLVFLQALVASKKQKLEQEATALLKESVELHFSNMQGLALGPEYFEKLDPLFL
VCIAKEYLHFCPKQPRSPGQLLSPLLKQVSMILSPVVKVAPGMLDPLFVTAQVKFLSGEL
ENAQSTLQRCLELDPNFVDAHLLMSQIYLAQGNFAMCSHCLELGVSHNFQVR--------
-------DHPLYHFIKAKALNKTGEYAEAIKTLKMIIKLPTIKAEDSRKP-RGPSVQPSE
RASILLELVEALRLNGELHEATKVMQDAINEFSGTPEEVRITIANVDLALSKGNVDLALS
MLRGITPKQPCYTEAKEKTASIYLNIRKDVRLYIGCY------MELCEH----LPGPHSS

PF13432 // ENSGT00390000005979_1_Domain_5 (841, 902)

LLLGDAFMSIQEPEKALEVYDEAYRKNPHDAILVSRIGQAYMKTHQYSKAINYYEAAQKI
S

ENSGT00390000005979_1_Linker_5_6 (902, 907)

GQDFL

PF13181 // ENSGT00390000005979_1_Domain_6 (907, 937)

CCELAELLLKLKKYHKAEKVLKQ-ALERD-

ENSGT00390000005979_1_Linker_6_7 (937, 1023)

SSGVKDIPSMMNEVKCLVLLA---
KVYKNHKK---EDVVETLNQALDLQSRILKRVPLEQPEMIPFQKQLAASICIQM---GEH
RL

PF14559 // ENSGT00390000005979_1_Domain_7 (1023, 1088)

TEKDYESALKSYKEALSYAPT-DNKVALELAQLHLLLGQLDLCEQCCSPLMMMEQTHE
RAAVMLADLMFRKQNYETAINLYRQVLEKAPDNFLVLNKLIDLLRRSGKLE-EAPAFFEL
AKKVSSRVPLEPGFNYCQGIYCWHIGQPNEALRFLNKARKDSTWGQIATCHMVQICLNPD
DEIVGGEVFESLVTDS-NS-ASRKESQQHGVRTAEKLLREFYPHS-DSGQTQLRLLQSLC
LLATREKANVETALGAFIEMAQTEKDSIPALLAMAQAYMLLKQVPKARTQLKRLAKIPWT
LNEAEDLEK

PF01535 // ENSGT00390000005979_1_Domain_9 (1330, 1354)

SWLLLADIYCQGGKFDLALDLLRRCLQYNKSCCKAYEYMGFIMEKEQSYKD
AATNYELAWKYSHQA----SPAIGFKLAFNYL----KDKKFVDAIEVCHS----------
----------------------VLMEHPNYPKIREEILEKAQGSLRP

------------------------------------------------------------
MNRSDSSLLATIVYYSQEKYFHHVQQAAAAGLERFNNDPVLHFFKAYGLLGEERIQEAIG
ELQSMR-SYPDVALCSIMALLYAHKCCE--TIDREAIEELEHSLKETRTSASASARYYAS
LFLWLAGHPDKAREYLDHSLKASNGSG----EGSVLRGWVDLSSDNPQVVKKSIKYLEQG
LQDSKDALGLMGKARYLMTQYNYSGALEVVNQLAVASANFLPALVLKMQLFLAQQNWEQV
VETAYRILERDQNNIDAYQTLAVYELAREGNMTTVSSLKTQK----AVEHVSNLIMALEM
REPQNPSLHLKKILVV-SRLCGRHQAVLHQVGSFLERIFLA-KPSY

PF00515 // ENSGT00390000005979_1_Domain_1 (407, 440)

AQVATELGYLLILR
NQVKEAFLWYSEAMNLDGN

ENSGT00390000005979_1_Linker_1_2 (440, 584)

SKAALTGIIWCQILEGHLEEAEHQLEFLKEVQ---------
QSLRKSEVLVFLQALLASKKNKGDLEVTALLQEAVELHFSSIQGLPMSCEYFEKLDPLFL
VCVAKEYLLFCSKQPRAPGQMVSPLLKQVTLILTPVVKAAPAL

PF00515 // ENSGT00390000005979_1_Domain_2 (584, 617)

MESMYVMAQVKYLSGEL
EKAQSTLKCCLELDPTFVDSHLLMAQICLAQGNLSMCSHCLEVGVSHNFQVR--------
-------DHPLYHFIKARALNKSGDHAEAIKTLKMIVRLPSMKVEEGKKC-RGPSLQPSE
RVSILLELADALRLNGELHEATKVIQDAINEFSGTPEEMRITIANADLSLSKGHVDTALS
MLRNITPKQPCYLEAKEKMADIYLHTHKDASLYVGCY------RELCEY----LPGPHSR
LLLGDAYMSIQQPEKALEVYEEACRKNPQD

PF00515 // ENSGT00390000005979_1_Domain_5 (871, 904)

ASLISRTGQAYVKTHQYTRAINYYEAAQKM
SGQDSVCCDLK--LLELKKFSRAERVLKQ-ALACX---XXKDIPSMIKDVEYLLLLA---
KVYKSHRR---EDVLETLNKALDVQARILKRVPLEQPEMLPSQKQLA

PF00515 // ENSGT00390000005979_1_Domain_7 (1008, 1045)

TSICIQF---GEH
YLAEKEYVKAVRSYKEALSFSPM-

ENSGT00390000005979_1_Linker_7_8 (1045, 1080)

DNQVMLELARIHLLQGHLDLCEQQCAALLHTEQTH

PF00515 // ENSGT00390000005979_1_Domain_8 (1080, 1113)

E
AAAAMMADLMFRKQKYEAAIHLYRQILEKVPDNFSVLDKLIDLLQRSGQLE-DAPAFFEL
ALRVSSRIPLEPGFNYCRGIYCWHIGQPNEALKFLNKARKDSTWGQRATYYMVQICLNPD
KEIMGGEAFENLSESN-S--ALRKELEQQGLRTAVKLLLEFGPHT-ATAHTQLRLLQNLC
LLATREKANMETALSTFIEMAQAERDSVPALLAMAQAYMLLKQIPKARTQLKRLAKAPWA
LPEAEDL

PF00515 // ENSGT00390000005979_1_Domain_9 (1328, 1361)

EKSWLLLADIYCQGGKFDLASELLRRCLQYNKSCCKAYEYMGFIMEKEQSYMD
AATNYELAWKYSHHA----SPAVGFKLAFNYL----KGKRFVEAIEVCHS----------
----------------------VLAEYPNYPKIREEILAKAQGSLKP

------------------------------------------------------------
MSTSDSSLMAGIIYYSQEQYFHHVQQAAALGLDKFSNDPVLQFFKTYGILREERIQDAIS
NLESIR-NHPDVSLCSIMALIYAHKCCA--AVDREAVQELENSLKEIRKTAGGTALYYAG
LFLWLVGHRDKAKEYIDRMLKVSSSPR----EGYVLRGWVDLTSDKPHLVKKSIKYLEQG
MQDSKDVLGLMGKATYFMLQQNYSEALEVVNQITGTSGSFLPALVLKMRLFLARQDWEQA
VETGHRILEKDESNIDACQILAVHELAREGNITIVSSFKTQE----------NLIKALET
REPQNPNLHLKKILVV-SRLCGRHQAILQLVCGFIERTFVA-TAAYAHVATELGYLFILQ
DQVKEASLWYSEAMKLDESSVAALTGIIWCQVLDGHLEEAEQQLEFMKEVQ---------
QCLGKSEVLVFLQALLASRKHKGEQEATRLLKEAAGLHFAGMQGLPLGSEYFEKLDPLFL
VCIAREYLFFCPKQPRSPGQIVSPLLKQVAVILNPVVKAAPALIDP

PF13181 // ENSGT00390000005979_1_Domain_2 (587, 616)

LYVMAQVKYLSGEL
ENAQSTLQRCLELDPTSVDPHLLMSHVYLAQGNFAMCSHCLELGVSHNFQVR--------
-------DHPLYHLVKARALNKCGDYPEAIRTLKMIIKLPTRKTEEGKKL-RGPTMQPSE
RASLLLELADALRLNGELHEATKVMQDAINEFSGTPEEIRITIANVDLALSSGNVDVALS
MLRNVTPKQPFYVEAKEKMANIYLQTRKDICLYIGCY------RELCEQ----LPGPHTS

PF13432 // ENSGT00390000005979_1_Domain_5 (841, 900)

LLLGDAFMNIQEPEKALEAYDEAYRKNPHDASLVSRIGQAYVKTHQYTKAINYYEAAQK

ENSGT00390000005979_1_Linker_5_6 (900, 907)

I
NGQDFL

PF13181 // ENSGT00390000005979_1_Domain_6 (907, 935)

CCDLAELLLKLKKFNKAEKVLKQ-ALERD--F-AKDLPSMMNNVKCLLLLA---
KVYKSHKK---EDVMGTLNKALDLQSQILKRVALEQPETIPSQKQLAASICVQF---GEH
HLAEKEFAKAVRSYKDALFYSPD-DNKVLLELARLYLLQGHLDLCEQHCADLLQTEKSHE
MASV

PF13432 // ENSGT00390000005979_1_Domain_8 (1085, 1142)

MMADLMFRKQKYEAAVNLYHQVLEKAPDNFLAWNKLIDLLWRSGRLE-DAPVFFEL
VKRMSSRVPLEPGFNYCRGIYCWRIGQPNKALKFLNKARKDSTWGQSATYYMVQICLNPD
NEVVGGEVFKNLVAES-NS-TDRKALEQHAVRTAEKLLRDFYPRS-DWGQTQL-------
---------------------------VPALLATAQAHALLKQVPKARTQLKRLAKAPWT
PDEAEDLEKSWLLLADVYCQGGKFDLASELLRRCVQYNKSCFRAYEYMGFIMEKEQAYKD
AAANYELAWKYSHHA----SPAVGFKLAFNYL----KDKRFVEAIEVCHT----------
----------------------VLGEHPNYPQIREEILEKAQGSLRP

------------------------------------------------------------
MSINDSSLMAGIIYYSQEKYFRHVQQAAAVGLEKFSNDPVLQFFKAYGVLREERIQDAIS
SLESIQ-NHPDVSLCSVMALIYAHKCCE--TIDREAIQELESSLKEIRKTAS

PF00515 // ENSGT00390000005979_1_Domain_0 (173, 206)

GTALYYAG
LFLWLMGRHDKAKEYIDRTLKVSSS

ENSGT00390000005979_1_Linker_0_1 (206, 407)

SR----EGYVLRGWVDLSSDKPHTVKKSIKYLEYG
IQDTKDVLGLMGKATYFMMLQNYSGALEVVNQITVAWGSFLPALVLKMRLFLARQDWEQT
VETGHRILEKDESNVDACQILAVHELAREGNITTVSSFKTQKA----AERVRNLIKALET
REPQNPSLHLKKILVV-GRLSGRHQAILQLVCSFLERTFMA-TSSY

PF00515 // ENSGT00390000005979_1_Domain_1 (407, 440)

AHVATELGYLFILQ
DQVKEASLWYSEAMKLDES

ENSGT00390000005979_1_Linker_1_2 (440, 584)

SMAALTGVIWCQILDGHLEEAEHQLEFLKEVQ---------
QSFGKSEVLVFLQALLASKKHKGEQEAAALLKEAAELHFSSTQALPLSTEYFERLDPLFL
VCIAKEYLVFCPKQPRSPGQIMSPLLKQVSVILHPVVKAAPAL

PF00515 // ENSGT00390000005979_1_Domain_2 (584, 617)

IDPLYLMAQVKYLSGEL
EYAQSTLQRCLELDPT

ENSGT00390000005979_1_Linker_2_3 (617, 670)

SVDAYLLMSQIYLAQGNFAMCSHCLELGVSYNFQVR--------
-------DH

PF00515 // ENSGT00390000005979_1_Domain_3 (670, 702)

PLYHFIKARALNKSGDYPEAIKALKMIIKLPN

ENSGT00390000005979_1_Linker_3_4 (702, 837)

LKMEESKKF-HGPSVRPSE
RVSILLELADALRMNGELHEATKVMQDTINEFSGTPEEIRITIANVDLALSKGNVDLALS
ILRNITPKQPCYMEAKEKMASIYLQTCKDVRLYIGCY------RELCEH----LPG

PF00515 // ENSGT00390000005979_1_Domain_4 (837, 870)

PHTS
LLLGDAFMNIQEPEKALEVYDEAYRKNPHDASLISRIGQAYVKTHQYTKAINYYEAAQKI
SGQDFLCHD

PF00515 // ENSGT00390000005979_1_Domain_6 (910, 935)

LAELLLKLKKFNKAEKVLKQ-ALDH

ENSGT00390000005979_1_Linker_6_7 (935, 1008)

D--F-VKDIPSLMNDVKCLLLLA---
KVYKSHKK---EDVMDTLNKAMDLQSRILKRVPLEQPEMIPSQKQLA

PF00515 // ENSGT00390000005979_1_Domain_7 (1008, 1045)

ASICIHF---GEY
YLAEKEYAKAVQSYKDALSYSPI-

ENSGT00390000005979_1_Linker_7_8 (1045, 1080)

DDKVVPELARLYLLQGHLDLCEQHCAILLQTEKNH

PF00515 // ENSGT00390000005979_1_Domain_8 (1080, 1113)

E
TASVMMADLMFRKQKYEAAINLYHQVLEKAPDNFPVLNKLIDLLRRSGKLE-DAPAFFEL
AKKVSSRVPLEPGFNYCRGIYCWHIGQPNEALKFLNKARKDSTWGQSAIYYMVQICLNPD
NEIVGGEAFENLVTES-NS-TDRKELEQHGVRTAEKLLREFYPHS-AWGQTQLRLLQSLC
LLATREKANVEAALGTFTEMAQAEKDSIPALLAMAQAYSLLKQVPKARTQLKRLAKAPWT
LAEAEDL

PF00515 // ENSGT00390000005979_1_Domain_9 (1328, 1361)

EKSWLLLADIYCQGGKFDLASELLRRCMQYNKS

ENSGT00390000005979_1_Linker_9_10 (1361, 1401)

CCKAYEYMGFIMEREQSYKD
AATNYELAWKYSHHA----N

PF00515 // ENSGT00390000005979_1_Domain_10 (1401, 1470)

PASGFKLAFNYL----KDKRFVEAIEVCHD----------
----------------------VLKEHPNYPRIREEILQKAQGSLRP

------------------------------------------------------------
MSSNDSSLMAGIIYYSQEKYFHHVQQAAAVGLEKFSNDPVLKFFKAYGVLKEEHIQDAIS
DLESIR-HHPDVSLCSTMALIYAHKRCE--IIDREAIQELEYSLKEIRKTVSGTALYYAG
LFLWLIGRHDKAKEYIDRMLKISRGFR----EAYVLRGWVDLTSDKPHTAKKAIEYLEQG
IQDTKDVLGLMGKAMYFMMQQNYSEALEVVNQITVTSGSFLPALVLKMQLFLARQDWEQT
VEMGHRILEKDESNIDACQILTVHELAREGNMTTVSSLKTQK----ATNHVRNLIKALET
REPENPSLHLKKIIVV-SRLCGSHQVILGLVCSFIERTFMA-TPSYVHVATELGYLFILK
NQVKEALLWYSEAMKLDKDGMAGLTGIILCHILEGHLEEAEYRLEF-----LKEADIGTE
TRSSLPQVLIFLQALLMSRKHKGEEETTALLKEAVELHFSSMQGIPLGSEYFEKLDPYFL
VCIAKEYLLFCPKQPRLPGQIVSPLLKQVAVILNPVVKAAPALIDPLYLMAQVRY

PF14559 // ENSGT00390000005979_1_Domain_2 (596, 634)

YSGEL
ENAQSILQRCLELDPASVDAHLLMCQIYLAQGNFGMCFHCLELGVSHNFQVR--------
-------DHPLYHLIKARALNKAGDYPEAIKTLKMVIKLPALKKEEGRKF-LRPSVQPSQ
RASILLELVEALRLNGELHEATKVMQDTINEFGGTPEENRITIANVDLVLSKGNVDVALN
MLRNILPKQSCYMEAREKMANIYLQTLRDRRLYIRCY------RELCEH----LPGPHTS
L

PF13432 // ENSGT00390000005979_1_Domain_5 (842, 900)

LLGDALMSILEPEKALEVYDEAYRRNPHDASLASRIGQAYVKAHQYTEAIEYYEAAQK

ENSGT00390000005979_1_Linker_5_6 (900, 907)

I
NGQDFL

PF13181 // ENSGT00390000005979_1_Domain_6 (907, 933)

CCDLGKLLLKLKKVNKAEKVLKQ-AL

ENSGT00390000005979_1_Linker_6_7 (933, 1022)

EHD--I-VQDIPSMMNDVKCLLLLA---
KVYKSHKK---EAVIETLNKALDLQSRILKRVPLEQPEMIPSQKQLAASICIQF---AEH
Y

PF14559 // ENSGT00390000005979_1_Domain_7 (1022, 1089)

LAEKEYDKAVRSYKDVFSYLPT-DNKVMLELAQLYLLQGHLDLCEQHCAILLQTEQNHE
TASVLMADLMFRKQKHEASINLYHQVLEKAPDNFLVLNKLIDLLRRSGKLE-DIPAFFEL
AKKVSSRVPLEPGFNYCRGIYCWHIGQPNEALKFLNKARKDSTWGQSAIYHMVQICLNPD
NEVVGGEAFENQGAES-NY-MEKKELEQQGVSTAEKLLREFYPHS-DSSQTQLRLLQGLC
RLATREKANMEAALGSFIQIAQVEKDSVPALLALAQAYVFLKQIPKARMQLKRLAKTPWV
LSEAEDLEKSWLLLADIYCQGSKFDLALELLRRCVQYNKSCYKAYEYMGFIMEKEQSYKD
AVTNYKLAWKYSHHGPHHDPRTQGFKLAFNYL----KDKKFVEAIEICNDV---------
-----------------------LREHPDYPKIREEILEKARRSLRP

------------------------------------------------------------
MSDDDAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRMQDAIN
DLESIR-KHPDTALCATLALIYAHKNCE--IVDGEALQELERSLKEVRKAPGEMALYYAG
LFLWLVGRHDKAKECVDRMLKVSVGSR----EGYVLRGWIDLTSDNPNTVKKSIRYLEQG
IQDTRDVLGVMGKATYLLLQQNYSGALEVVSQLTVASPGFLPALVLKMRLFLAKQDWEQT
IETAQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-----XXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXCGRQQPILRLVCSFIERTFVA-TPSH

PF00515 // ENSGT00390000005979_1_Domain_1 (407, 440)

GHVATELGYLFILQ
DQLKEAELWYSEAVKLDANNIAALKGIIWCLLLEGHLEEAEQQLEFLKEVQ---------
QSLGRSEVLAFLQALLVSRKHKAEQEATALLKEAAELHFSSMQGLPLSPEYFEQLNPFFL
VFIVREHLLFCPKQPRSPGQIVSPLLKQAAMILSPVIKAAPGLTEPLYLSAQVKYLSXXX
XXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXV---------
------RDH

PF00515 // ENSGT00390000005979_1_Domain_3 (670, 699)

PLYHFIKARALNKSGDYPEAIKALKMIVK

ENSGT00390000005979_1_Linker_3_4 (699, 837)

LPIQRVEEVRKS-RGPSVGPSE
RVAILLELADALRLNGELHEATKVIQDAINEFSGTQEEIRITLANVDLALSKGNVDAALS
MLRNVTPRQPCYTEAKEKMASIYLQTRKDVRLYIGCY------RELCEN----LPG

PF07719 // ENSGT00390000005979_1_Domain_4 (837, 870)

PHTS
LLLGDAFMHIQEPEKALEVYDEAYRKNPHDASLVSRIGQAYMKTHQYGKAVNYYEAAQKI
GAQDFL

PF00515 // ENSGT00390000005979_1_Domain_6 (907, 941)

CCDLAELFLKLKKFAKAERVLKQ-ALEHD---FA

ENSGT00390000005979_1_Linker_6_7 (941, 1008)

NDLPSMMTVVKCLLLLA---
KVYKHNKR---EEVMETLNK-LDLQSRILKR-ALEQPEMIPLHKQLA

PF00515 // ENSGT00390000005979_1_Domain_7 (1008, 1045)

ASICVQF---GEF
HFTEQEYSQAVRAYQDALSYSPT-

ENSGT00390000005979_1_Linker_7_8 (1045, 1080)

DNKVVLELARLCLLQGQLDLCEQHCAILLQTEKDD

PF07719 // ENSGT00390000005979_1_Domain_8 (1080, 1113)

E
AALVMMADLMFRKQNYDGAKGLYQQVLEKTPDNFLVLNKIIDLLRRSGKLE-DALSLFER
AQKESSRMPLEPGFHYCKGIS-LHLGKPNEALKFLNKARKDSTWGQSAIHHMVQICLNPD
KEIVGGEALENLMAEN-TTSEKKDPEQHGGVRTAEKLLRECYPHS-AMGQAQQRLLQGLC
LMATRERGNVEEALNTFIHMAQAEKNNAAALLAMAQAYSLLKQVLKARTQLIRQAKALWT
LGEAEDLEKSWLLLADIYCQGGKFDLVSELLRC-V-HARSCCKAYEYMGFIMEKEQSYKD
AAANYELAWKHSHHT----N

PF00515 // ENSGT00390000005979_1_Domain_10 (1401, 1470)

PSVGFKLAFNYL----KDKRFVEAIDVCHR----------
----------------------VLREYPNYPKIREEILEKAQGSLRP

------------------------------------------------------------
MSSNDSSLMAGIIYYSQEKYFHHVQQTAAVGLEKFSNDPVLKFFKAYGVLKEEHIQDAIS
DLESIR-HHPDVSLCSTMALIYAHKRCE--IIDREAIQELEYSLKEIRKTVSGTALYYAG
VFLWLIGHHDKAKEYIDRMLKISRGFR----EAYVLRGWVDLTSDKPHTAKKAIEYLEQG
IQDTKDVLGLMGKAIYFMMQQNYSEALEVVNQITVTSGSFLPALVLKMQLFLARQDWEQT
VEMGHRILEKDESNIDACQILAVHELAREGNMITVSSLKTQK----ATNHVRNLIKALET
REPENPSLHLKKLLVV-SRLCGSHQVILGLVCSFIERTFMA-TPSYIHVATELGYFFILK
NQVKEALLWYTEAMKLDKDGMAGLTGIILCHILEGHLEEAEHQLEF-----LKEVQKSL-
---GKSEVLIFLQALLTSKKHKGEQETTALLKEAVELHFSSMQGLPLGSEYFEKLDPYFL
VCIAKEYLLFCPKQPRLPGQIVSPLLKQVAVILNPVVKAAPALIDPLYLMAQVRYYSGEL
ENAQSILQRCLELDPASVDAHLLMCQIYLAQGNVGMCFHCLELGVSHNFQVR--------
-------DHPLYHLIKARALNKAGDYPEAIKTLKMVIKLPALKKEEGRKF-LGPSLQTSQ
RASILLELVEALRLNGELHEATKVMQDTINEFGGTPEENRITIANVDLVLSKGNVDVALN
MLRNISPKQSCYMEAREKMASVYLQTLRDRRLYIRCY------RELCEH----LPGPHTS
LLLGDALMSILEPEKALEVYDEAYRQNPHDASLAS

PF00515 // ENSGT00390000005979_1_Domain_5 (876, 902)

RIGQAYVKAHQYTEAIEYYEAAQKI
NGQDFLCCDLAELLLKLKKINKAEKVLKQ-ALEHD--I-VQDIPSMMNDVKCLLLLA---
KVYESHKK---EAVIETLNKALDLQSRILKRVPLEQPEMIPSQKQLAASICIQF---AEH
YLAEKEYDKAVRSYKDVFSYLPT-DNKAMLELAQLYLLQGHLDLCEQHCAILLQTEQNHE
TASVLMADLMFRKQKHEAAINLYHQVLEKVPDNFLVLNKLIDLLRRSGKLE-DIPAFFEL
AKKVSSRVPLEPGFNYCRGIYCWHIGQPNEALKFLNKARKDSTWGQSAIYHMVQICLNPD
NEVVGGEAFENQGAES-NY-TEKKELEQQGVSTAEKLLHEFYPNS-ASSQTQLRLLQGLC
RLATKEKANMEAALGSFIQIAQAEKDSVPALLALAQAYVFLKQIPKARMQLKRLAKAPWV
LSEAEDLEKSWLLLADIYCQGSKFDLALELLRRCVRYNKSCYKAYEYMGFIMEKEQSYKD
AVTNYKLAWKYSHHA----NPAIGFRLAFNCL----KDKKFVEAIEICHDV---------
-----------------------LREHPNYPKIREEILEKARRSLRP

------------------------------------------------------------
---------ARIIYYSQEKYFRHVQQAAAMGLEKFSNDPVLQFFKAYGVFREERIQDAIN
NL-SIR-NHSDVSLCSIMVLIYAHKCCE--TIDQEAIQELESSLKEVRKVAS

PF00515 // ENSGT00390000005979_1_Domain_0 (173, 206)

GTALYYAG
LFLWLLGRHDKAKEYIDRMLKVSSS

ENSGT00390000005979_1_Linker_0_1 (206, 407)

SR----EDY-LRGWVDLTSDKPHTVKKSIKYVEQG
IQDTKDVLGLMGKATYYMTQQNYSGALEVVNQITVASGSFLPALVLKMKLFLARQDWEQT
VETGHRILEKDESNIDACQILAVHELAREGNVTTVSSFETKA-----AEHVRNLIKALET
REPQNPSLHLNKILVV-SRLCGKHQVILRLVCSFIERTFIA-TPFY

PF00515 // ENSGT00390000005979_1_Domain_1 (407, 440)

AHMATELGHLFILQ
DQVKEASLWYSEAMKLDES

ENSGT00390000005979_1_Linker_1_2 (440, 584)

NVAALTGIIWCQILEGRLEEAEHQLEFLKEVQ---------
QSLGKSEVLIFLQALLASRKHKGEQEATALLKEAVELHFSGMQGLPLGSEYFEKLDPLFL
VCIAREYLFFCPRQPRLPGQIVSPLLKQVAVILNPVVKAAPAL

PF00515 // ENSGT00390000005979_1_Domain_2 (584, 617)

IDPLYVMAQVKYLSGEL
ENAQSTLQRCLELDPTSVDAHLLMSQIYLAQGNFSMCSHCLELGVSHNFQVR--------
-------DHPLYHFIKARALNKSGDYPEAIKTLKMITKLPAVKMEEGKKT-RGPSVRPSE
RVSILLELVDALRMNGELHEATKVMQDAINEFSGTPEEIRITIANVDLALSKGNVDMALN
MLRNITPKQPCYIEAKEKMASIYLHTHKDIRLYVGCY------RELCEH----LPGPQTS
LLLGDAFMNIQEPEKALEVYDEAYRKNPHD

PF07719 // ENSGT00390000005979_1_Domain_5 (871, 904)

ASLVSRIGQAYVKTHQYAKAINYYEAAQKI
SGQ

ENSGT00390000005979_1_Linker_5_6 (904, 908)

DFLR

PF00515 // ENSGT00390000005979_1_Domain_6 (908, 935)

CDLAELLLKLKKFSKAEKVLKQ-ALEH

ENSGT00390000005979_1_Linker_6_7 (935, 1008)

D--F-VKEIPSMMNDVKCLLLLA---
KVYRSHKK---EDVLETLNKAMDLQSRILKRVPLEQPEMIPSQKEMA

PF00515 // ENSGT00390000005979_1_Domain_7 (1008, 1045)

ASICVQF---GEH
YLAEKDYAKAVQSYKDALSYSPT-

ENSGT00390000005979_1_Linker_7_8 (1045, 1080)

DNKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX

PF00515 // ENSGT00390000005979_1_Domain_8 (1080, 1113)

X
XXXXMMADLMFRKQDYEAAINLYHQVLEKVPDNFSVLNKLIDLLRRSGKLE-DAPAFFEL
AKKLSSRVPLEPGFNYCTGIYCWHIGQPNEALKFLNKARKDSTWGQSATYYMVQICLNPD
NEIVGGEALENLVAES-NS-PGIMESEQHGVRTAEKLLREFYPHT-AWGQTQLLLLQGLC
LLATSEKANVEAALGTFIEMAQAEKDSVPALLAVAQAYMLLKQVPKARTQLKRLAKAPWA
MAEAEDL

PF00515 // ENSGT00390000005979_1_Domain_9 (1328, 1361)

EKSWLLLADIYCQGGKFDLASELLRRCVQYNKSCCKAYEYMGFIMEKEQSYKD
AATNY-------------------------------------------------------
-----------------------------------------------

------------------------------------------------------------
MSSDDSSLMASIIYYSQEKYFHHVLQAANVDLERYSNDPVLQFFRAYGALGEDHIHDAIS
ELESIQ-SHPDTSLCAVIALISAHKCCD--TIDVEAIQELESSLKEIRRTASSTALYYAS
LFLWFMGHHDKAREYVDHMLKVSSGSK----EGYVLRGWVDLTSSKPHIVKKSIKYLEQG
TQDTKDVLGLMGKAMYFMTQQNFSRALEVVNQVTLACSNFLPALVLKMKLFLARQDWDQT
IETGQRILEKDENNIDAWQILAVHELVKEGNTDRA------------ADRVRNLIKALET
GEPHNPNLHLKKILAV-SRLCGRHQVVHRLVSGFLERIFMA-TPSCALVATELGYLFILQ
QQVKEACLWYKEAMKLEENRLAALAGSIWCQILQGQLEEAAHQLEFLKEVQ---------
QSLGKSELLVFLQALVVAKKEKLEQEATALLKEAVELHFSNMQGLALSPEYFEKLDPLFL
VCIAKEYLHFCPKQPRAPGQLVSPLLKQVTMILSPVVKVAPAMMEPLYVMAQVKFLSGEL
ENVQSTLQRCLELDPTFVDAHLLMSQIHLAQGNFAMCSHCLELGVSHNFQVR--------
-------DHPLYHFIKARALNKTGNYTEAIKTLKMIIKVPTSKAEEGRKS-RSPSVRPSE
RASILLELVEALRLNGELHEATKIMQDAINEFSGTPEEMRITVANVDLALSKGNVDLALN
MLRGITPKQPCYTEAKEKMASIYLHTRKDMRLYIGCY------AELCEH----LPGPHSS

PF13432 // ENSGT00390000005979_1_Domain_5 (841, 901)

LLLGDAFMNIQEPEKALEVYDEAYRKNPHDASLVSRIGQAYVKTHQYVKAINYYEAAQKI

ENSGT00390000005979_1_Linker_5_6 (901, 907)

SGQDFL

PF13181 // ENSGT00390000005979_1_Domain_6 (907, 935)

CCELAELLLKLKKYHKAEKVLKQ-ALER

ENSGT00390000005979_1_Linker_6_7 (935, 1022)

D--SGVKDIPSMINEVKCLLLLA---
KVYKSHKK---EEVMETLNLALDLQSRILKRVPLEQPEMIPFQNQLAASICIQT---GEH
H

PF14559 // ENSGT00390000005979_1_Domain_7 (1022, 1088)

LEEKDYDSAMKSYKDALAYSPT-DSKVVLELAQLYLLQGQLDLCEQRCAPLLEMEQTHE
RAAVMLADLMFRRQDYETAISLYRQVLEKAPDNFLVLNKLVDLLRRSGKLE-EAPAFFEL
AKKVSSRVPLEPGFNYCQGIYCWHIGQPNEALRFLNKARKDSTWGQLATCYMVQICLNPD
NEIVGGEAFESLVGDS-NS-ASRRESHQHGVRTAEKLLREFYPHS-ESGQTQLRLLQNLC
LLATREKANVEVALGAFIEMAQAEKDSIPALLAMAQAYILLKQVPKARTQLKRLAKVPWM
VDEAEDLE

PF13181 // ENSGT00390000005979_1_Domain_9 (1329, 1360)

KSWLLLADIYCQGGKFDLALELLRRCLQYNKSCCRAYEYMGFIMEKEQSYKD
AATNYELAWKYSHQA----NPAIGFKLAFNYL----KDKKFVDAIEVCHS----------
----------------------VLTEHPNYPKIREEILEKAQGSLRP

------------------------------------------------------------
-----MQEDAGIIYYSQEKYFHHVQQAASTGLERFSNDPVLQFFKAFGILGEERIHDAIS
ELESIK-SYPDMCLCSVIALLYAHKRCD--TIDGEAVQELESSLKEIRKTASDTALYYAS
LFFWLIGHHDKAREYVDHMLKVCSGSR----EGYILKGWVDLTCNKPHIVKKSIKYLEQG
TQDTKDVLGLMGKATYFMMQQNFSGALEVVNQVTAASGNFLPGLVLKMQLFLARQDWEQT
VETGHRILEKDENNIDAWQILAVHELVREGNMTTA------------ADHVRNLIKALEA
REPQNPSLHLKKILVV-SRLCGRHQAVQRLVSSFMERIFMS-TPSCALVATELGYLFILQ
HQVKEACQWYKEAMKLE-NRLATLAGNIWCLILQGQLEEAAYQLEFLKAVQ---------
QSLGKSEVLFFLQALVASKKQNGEQEATELLKEAVELHFSSMQGLPLGPEYFEKLDPLFL
VCIAKEYLHFCPKQPRSPGQLVSPLLKQVTMILSPVVKAAPAMMDPLYVTAQVKFLSGEL
ENAQSTLQHCLELDPTFVDAHLLMSQIYLAQDNFAMCFHCLELGVSHNFQVR--------
-------DHPLYHFIKARALNKTGDYAEAIKTLKMIMKLPTMKLEEGKKF-PGPSVQPSE
RASILLELVEALRLNGELHEATKIMQDAINEFSGTPEEMRITVANVDLALSKGHVDMALN
MLRGITPKQPYYTEAREKMASIYLHTRKDIRLYIGFPLGQTVPFPLCQH----LPGPHSS

PF13432 // ENSGT00390000005979_1_Domain_5 (841, 901)

LLLGDAFMSIQEPEKALEVYDEAYRKNPRDASLVSRIGQAYVKTHQYSKAINYYEAAQKI

ENSGT00390000005979_1_Linker_5_6 (901, 906)

SGQDF

PF13181 // ENSGT00390000005979_1_Domain_6 (906, 938)

MCCDLAELLLKLKKFHKAEKILKQ-ALDRD--

ENSGT00390000005979_1_Linker_6_7 (938, 1022)

SAVKDIPSMMHEVKCLLLLA---
KVYKSHKK---EEVVQTLNQALDLQSRILKRVPLEQPEMIPFQKKQAASICIQF---GEH
Y

PF14559 // ENSGT00390000005979_1_Domain_7 (1022, 1087)

LAEKDYPSAVRSYKDALSYSPT-DNKVVLELARLYLLQGHLDLCEQHCGALLRMEQTQE
TAQVMLADLMFRKQNYEAAISHYRQVLEKAPDNFSVLNKLMDLLRRGGKLE-EAPAFFDL
ARKVSSRVPLEPGFSYCQGIYCWHIGQPNEALKFLNKARKDSTWGHNATYYMVQICLNPD
NEIIGGEAFESLLADG-NS-ASRKECQQQGVRTAEKLLREFYPHS-DSGHTQLRLLQSLC
LLATREKANVEVALGTFIEMAQAEKDSIPSLLAMAQAYMLLKQIPKARTQLKRLAKAPWT
LEEAEDLE

PF13181 // ENSGT00390000005979_1_Domain_9 (1329, 1360)

KSWLLLADIYCQSGKFDLATELLRRCLQYNKSCCKAYEYMGFIMEKEQSYKD
AATNYELAWKYSHQA----NPSIGFKLAFNYL----KDKKFVDAIEVCHS----------
----------------------VLTEHPNYPKIREEILEKAQGSLRP

------------------------------------------------------------
MSGSDSSLLAGIVYYSREKYFHHVQQVVAVGLEKFSNDPVLQFFKAYGVLREKRVQDAIS
ELENIR-SHPDLSLCSAMALLYAHRCCE--TIDREAIQELESSLKEVRRLASEAALYYAG
LFLWLMDYHDKAREYVDHMLKVSSGFR----EGYVLKGWVDLTSEKPHVVKKSIKYLEQG
IQSNKDMLGLMGKATYLMMQHNYSGALDVVNQISATSGSFLPALVLKMQLFLAQQDWEQT
METAHRILEKDESNIDACQILTVHELAREGNITTA------------TDHVRNLIKALEM
REPQNPSLQLKKILVV-SRLCGRHPAILRLLSSFMERIFLA-MPSCAQVATELGYLFILQ
NQEKDAALWYSEATKLGENSMAALTGTIWCHILKDELEEAEHQLEFLKEVQ---------
QSLGRSEVLVFLEALLASKKHKGEQEVTALLREAAELHFSHTQGLPLGPEYLEKLDPPFL
VCIAKEYLQFCPKQPRAPGQLMSPLLKQAAVILSPVVRTAPALVDPLYVMGQVKYLSGEL
ENAQSTV

PF13431 // ENSGT00390000005979_1_Domain_2 (608, 637)

QRCLELDPTSADAHLLLAQIYLAQGNFAMCSHCLELGVSHNFQVR--------
-------DHPLYHFIKARALNKSGDYQEAIKTLKMIMKLPTLKTEESRKT-RGPSMQPSE
RASILLELVDALQLNGELHEATKVMQDAINEFSGTAEEIRITIANVDLALSKGNVDLALS
MLKDITPKQPCYTEAKEKMASIYLQTRKDTCLYIACY------RELCEH----LPGPHTS

PF13432 // ENSGT00390000005979_1_Domain_5 (841, 902)

LLLGDAFMNIQEPEKALEVYDEACRKNPHDASLVSRIGQAYVKTHQYSKAINYYEAAQKI
S

ENSGT00390000005979_1_Linker_5_6 (902, 907)

GQDFL

PF13181 // ENSGT00390000005979_1_Domain_6 (907, 932)

CCDLAELLLKLKKFNKAEKVLKQ-A

ENSGT00390000005979_1_Linker_6_7 (932, 1010)

LGHD--F-VKDIPSMMNDVKCLLLLA---
KVYKSYKK---EEVLETLNKALNLQTRILKRVPLEQPEMLPSQKQLATS

PF13181 // ENSGT00390000005979_1_Domain_7 (1010, 1043)

ICMLF---GEF
YSAEKDYAKGVQSYRDALSYSP

ENSGT00390000005979_1_Linker_7_8 (1043, 1091)

T-DNKVVLELARLSLLQGYLDLCEQHCAVLLQTDQTHE
TASLMMADFM

PF13432 // ENSGT00390000005979_1_Domain_8 (1091, 1145)

FRKQNYEAAINLYHQVLEKAPDNFSVLDKLIDLLRRSGKLD-EAPAFFQL
AKKR

ENSGT00390000005979_1_Linker_8_9 (1145, 1329)

SSRVPMEPGFNYCRGIYCWHTGQPNQALKFLNKARKDTTWGQRANYYMVHICLNPD
NEIVGGEAFENQLTKS------KKESEQQGVRTAEKLLRDFYPLS-AFGQTQQRLLQSLC
LLATREKTNVEAALETFLEIAQSEKDSVPALLGMAQACMLLKQVPKARTQLKRLAKAPWT
LAEAEDLE

PF13181 // ENSGT00390000005979_1_Domain_9 (1329, 1360)

RSWLLLADIYSSGGKFDLASELLRRCIQYNKSCYKAYEYMGFIMEKEQSYKD
AATNYELAWKYSHQA----SPAIGFKLAFNYL----KDKKFVEAIEVCHN----------
----------------------VLREHPSYPKIREEILEKARRSLRP

------------------------------------------------------------
MSSDDSSLMASIIYYSQEKYFHHVQQAASVGLERYSNDPVLQFFKAYGALGEDHIHDAIS
ELEGIQ-SHPDMALCSVIALLYAHKCCD--IIDGEAVQELECSLKEIRKTASDTALYYAG
LFLWLVDRHDKAREYVDHMLKVCSGSK----EGYVLRGWVDLTSNKPHVVKKSIKYLEQG
TQDTKDVLGLMGKATYFMTQQNFSRALEVVNQVTTASGNFLPALVLKMRLFLARQDWDQT
IETALRILEKDESNIDAWQILTVHELVREGSTATA------------TDRVRSLIKALET
REPQNPSLHLKKILVV-SRLCGKHQEVQRLVSGFLERIFMA-TPSCALVATELGYLFILQ
QQVKEACLWYKEAMKLEENRLDALAGSIWCQILQGQLEEAANQLEFLKEVQ---------
QSLGKSEVLVFLQALVASKKQKQAQEATALLKEAVELHFSSMQGLALSPEYFEKLDPLFL
VCIAKEYLHFCPKQPRSPGQLVSPLLKQVAMILSPVVKVAPAMMEP

PF13181 // ENSGT00390000005979_1_Domain_2 (587, 616)

LYVMAQVKFLSGEL
ENAQSTLQRCLELDPTLVDAHLLMSQIYLAQGNFAMCSHCLELGVSHNFQVR--------
-------DHPLYHFIKARALNKTGDYAEAIKTLKMIIKLPTTKAEENKKL-RGPSIQPSE
RASILLELVEALRLNGELHEATKIMQDAINEFSGTPEEMRITIANVDLALSKGNVDLALS
MLRGITPKQPCYTEAKEKMASIYLNTRKDVRLYIGCY------MELCEH----LPGPHSS

PF13432 // ENSGT00390000005979_1_Domain_5 (841, 902)

LLLGDAFMNIQEPEKALEVYDEAYRKNPHDASLVSRIGQAYMKTHQYTKAINYYEAAQKI
S

ENSGT00390000005979_1_Linker_5_6 (902, 907)

GQDFL

PF13181 // ENSGT00390000005979_1_Domain_6 (907, 935)

CCELAELLLKLKKYHKAEKVLKQ-ALEQ

ENSGT00390000005979_1_Linker_6_7 (935, 1022)

D--SGVKDIPSMMNEVKCLLLLA---
KVYKSHKK---EDVVETLNQALDVQSRILKRAPLEQPELIPFQKQLAASICIQI---GEH
Y

PF14559 // ENSGT00390000005979_1_Domain_7 (1022, 1088)

LAEKDFDSAVKSYKDALSYSPT-DNKVALELAQLHLLQGQLDLCEQRCGPLLQIEQTHE
RAAVMLADLMFRKQNYETAINLYRQVLEKAPDNFLVLNKLIDLLRRSGKLE-EAPAFLEL
AKKVSSRVPLEPGFNYCQGIYYWHIGQPNEALRFLNKARKDSTWGQIATCYMVQICLNPD
NEVVGGEVFESLVADS-NS-AGRKESQQHGVRTAEKLLREFYPHS-DSGQSQLRLLQSLC
LLATREKANVEVALGAFIEMAQAEKDSIPALLAMAQAYMLLKQVPKARTQLKRLAKVPWT
LDEAEDLE

PF13181 // ENSGT00390000005979_1_Domain_9 (1329, 1360)

KSWLLLADIYCQGGKFDLALELLRRCLQYNKSCCKAYEYMGFIMEKEQSYKD
AATNYELAWKYSHQA----SPAIGFKLAFNYL----KDKKFVDAIEVCHS----------
----------------------VLTEHPNYPKIREEILEKAQGSLRL

------------------------------------------------------------
MSSSDSSLMAGIIYYSQEKYFRHVQQAAAVGLEKFSHDPVLQFFKAYGVLKEEHIQDAIS
DLESIR-HHPDVSLCSTMALIYAHKRCE--TIDREAIQELECSLKDIRKTASGTALYYAG
LFLWLMGRRDKAKEYINHMLKVSRGFR----EGYVLRGWVDLTSDKPHTAKKAIEYLEQG
IQDTKDVLGLMGKARYLMMQQKYSEALEVVNQITVTSGSFLPALILKMQLFLARQDWEQT
VEMGHRILEKDESNIDACQILAVHELAREGNMTTVSYLKIQK----ATNHVRNLIKALET
REPQNPSLHLKKILVV-SRLCGSHQVILGLVCSFIERTFMA-TPSYAHVATELGYLFILK
NQVKEALLWYSEAMKLDKDSMAALTGIIWCHILEGHLEEAEHQLEFLKEVQ---------
QSLGKSKVLVFLQALLTSKKHKGEQEATALLEEAVELHFSGMRGLPLGSGYLEKLDPHFL
VCIAKEYLLFCPKQPRFPGQILSPLLQQVAVILNPVVKAAPALIDPLYLMAQVRYYS-EL
ENAQSTLQRCLELDPTSVDAHLLMCQIYLAQGNFGMCFHCLELGVSHNFQVR--------
-------DHPLYHLIKARALNKAGDYPEAVKTLKMVIKLPALKKEESRKL-LRSSVQPSQ
RASILLELVEALRLNGELHEATKVMQDTINEFSGTPEENRITIANVDLVLSKGNVDVALN
MLRNITSKQSCYMEAREKMASIYLQTLRDRHLYIGCY------RELCEH----LPGPHTS
L

PF13432 // ENSGT00390000005979_1_Domain_5 (842, 900)

LLGDAFMSILEPEKALEVYDEAYRQNPQDASLASRIGQAYVKAHQYTEATEYYEAAQK

ENSGT00390000005979_1_Linker_5_6 (900, 907)

I
NGQDFL

PF13181 // ENSGT00390000005979_1_Domain_6 (907, 933)

CCDLAELLLKLKKINKAEEVLKQ-ALEHD--I-VQDIPSMMNDVKCLLLLA---
KVYKSHKK---EAVTETLKKALDLQSRILKRVPLEQPEMIPSQKQLAASICIQF---AEH
YLAEKEYEKAVRSYKDALSYLPT-DNKVMLELAQLHLLQGHLDLCEQHCAILMQTDQHHE
TA

PF13174 // ENSGT00390000005979_1_Domain_8 (1083, 1113)

SVLMADLMFRKQEHDAAVNLYHQVLEKAPDNFLVLNKLIDLLRRSGKLE-DIPAFFEL
AKKVSSRVPLEPGFNYCSGIYCWYTGQPNEALKFLNKARKDRTWSQSAIYHMVQICLNPD
NEVVGGEAFENQEAEI-NY-TEKKELEQQGVSTAEKLLCEFHPHS-ASSQTQLQLLQGLC
QLATREKANMEAALGKFLQIAQAEKESIPALLALAQAYVFLKQIPKARMQLKRLAKAPWM
LSEADDLE

PF13181 // ENSGT00390000005979_1_Domain_9 (1329, 1360)

KSWLLLADIYCQGGKFDLASELLQRCVRYNKSCYKAYEYMGFIMEKEQSYKD
AVTNYKLAWKYSHHA----SPAVGFRLAFNYL----KDKKFVEAIEICHDV---------
-----------------------LREHPNYPKIREEILEKARRSLRP

------------------------------------------------------------
MSSNDSSLMAEIIYYSQEKYFHHVQQAAAVGLEKFSNDPVLKFFKAYGVLKEEHIQDAIS
DLESIR-HHPDVSLCSTMALIYAHKRCE--IIDREAIQELEYSLKEIRKTVSGTALYYAG
LFLWLIGRHDKAKEYIDRMLKISRGFR----EAYVLRGWVDLTSDKPHTAKKAIEYLEQG
IQDTKDVLGMMGKAMYFMMQQNYSEALEVVNQITVTSGSFLPALVLKMRLFLARQDWEQT
VEMGHRILEKDESNIDACQILTVHELAREGNMTTVSSLKTQK----AANHVRNLIKALET
REPENPSLHLKKILVV-SRLCGSHQVILGLVCSFIERTFVA-TPSYVHVATELGYLFILK
NQVKEALLWYSEAMKLDKDGMAGLTGIILCHILEGHLEEAEYRLEF-----LKEVQKSF-
---GKSEVLIFLQALLMSKKHKGEQETTALLKEAVELHFSSMQGIPLGSEYFEKLDPYFL
VCIAKEYLLFCPKQPRLPGQIVSPLLKQVAVILNPVVKAAPALIDPLYLMAQVRYYSGEL
ENAQSILQRCLELDPASVDAHLLMCQIYLAQGNFGMCFHCLELGVSHNFQVR--------
-------DHPLYHLIKARALNKAGDYPEAIKTLKMVIKLPALKKEEGRKF-LRPSVQPSQ
RASILLELVEALRLNGELHEATKVMQDTINEFGGTPEENRITIANVDLVLSKGNVDVALN
MLRNISPKQSCYMEAREKMANIYLQTLRDRRLYIRCY------RELCEH----LCGPHTS
LLLGDALMSILEPEKALEVYDEAYRQNPHDASLAS

PF00515 // ENSGT00390000005979_1_Domain_5 (876, 902)

RIGQAYVKAHQYTEAIEYYEAAQKI
NGQDFLCCDLGELLLKLKKVNKAEKVLK--ALEHD--I-VQDIPSMMNDVKCLLLLA---
KVYKSHKK---EAVIETLNKALDLQSRILKRVPLEQPEMIPSQKQLAASICIQF---AEH
YLAEKEYDKAVRSYKDVFSYLPT-DNKVMLELAELYLLQGHLDLCEQHCAILLQTEQNHE
TASVLMADLMFRKQKHEAAINLYHQVLEKAPDNFLVLNKLIDLLRRSGKLE-DIPAFFEL
AK-VSSRVPWEPGFSYCRGIY--HIGQPNEALKFLNKARKDSTWGQSAIYHMVQICLNPD
NEVVGGEAFENQGAES-NY-MEKKEVEQQGVSTAEKLLHEFHPHS-DSSQTQLRLLQGLC
RLATREKANMEAALGSFIQIAQAEKDSVPALLALAQAYVFLKQIPKARMQLKRLAKTPWV
LSEAEDLEKSWLLLADIYCQGSKFDLALELLQRCVRYNKSCYKAYEYMGFIMEKEQSYKD
AVTNYKLAWKYSHHT----NPAIGFKLAFNYL----KDKKFVEAIEICNDV---------
-----------------------LREHPNYPKIREEILEKARRSLRP

------------------MDCN-----CNRPPRRSAHDPTAGIPLHTAPQTRTRSRERPE
MSSNDSSLMAGIIYYSQEKYFRHVQQAAAVGLEKFSNDPVLQFFKAYGVLKEEHIQDAIS
DLESIR-PHPDMSLCSTMALIYAHERCE--TIDREAIQELECSLKEMSKTASGTALYYAG
LFLWLMGRHDKAKEYINHMLKVSRGFR----EGYVLRGWVDLTSGKPHTAKKAIEYLEQG
IQDTKDVLGLMGKASYFMMQQNYSEALEVVNQIIVTSGSFLPALILKMQLFLARQDWERT
VEMGHRILEKDESNIDACQILAVHELAREGNMTT------------ATNHVRNLIKALET
REPQNPSLHLKKILVV-SRLCGSHQVILGLVCSFIERTFMA-TPSHAHVATELGYLFILK
NQVKEALLWYSEAMKLDSDGMTALTGIIWCHILEGHLEEAEHQLEFLKEVQ---------
QSLGKSKVLVFLQALLTSKKHSGEQEAAALLKKAVELHFSGMQGLPLGSEYLEKLDPHFL
VCIAKEYLLFCPKQPRFPGQIVSPLLQQVAVILNPVVKAAPALIDP

PF13181 // ENSGT00390000005979_1_Domain_2 (587, 616)

LYLMAQVRYYSGEL
ENAQSTLQRCLELDPTSVDAHLLMCQIYLTQDNFGMCFHCLELGVSHNFQVR--------
-------DHPLYHLMKARALSKAGDYPEAIKTLKMVIKLPALKKEEGRKL-LGPSVQPSQ
RASILLELVEALRLNGELHEATKVMQDTINEFSGTPEENRITIANVDLVLSKGNVDVALN
MLRHITSKQSCYMEAREKMANIYLQTLRDRHLYIGCY------RELCER----LPGPHTS
LLLGDAFMSILEPEKALEVYHEAYRQRPQDTSLAS

PF13181 // ENSGT00390000005979_1_Domain_5 (876, 903)

RIGQAYVKAHQYTEATEYYEAAQKI
NGQDFLCCDLAELLLKLKEANKAEKVLKQ-ALEHD--V-VQDTPSMMNDVKCLLLLA---
KVYKSHKK---EAVIETLKKALDLQSRILKRLPLEQPEIIPSQKPLAASICIQF--

PF13432 // ENSGT00390000005979_1_Domain_7 (1017, 1063)

-AEH
YLAEKEYDKAERAYEDALSYLPT-DNKVMLELAQLHLLQGHL

ENSGT00390000005979_1_Linker_7_8 (1063, 1083)

DLCEQHCAILMQTDQSHE
TA

PF13174 // ENSGT00390000005979_1_Domain_8 (1083, 1113)

SVLMADLMFRKQEHDAAINLYHQVLEKAPDNFLVLNKLIDLLRRSGKLE-DIPAFFEL
AKKVSSRVPLEPGFNYCRGIYCWHTGQPNEALKFLNKARKDSTWGQSAIYHMVQICLNPD
NEVVGGEAFENQEAEV-NY-TEKKELEQLGVSTAEKLLCEFHPHS-ASSQTQLRLLQGLC
RLATREKANIEAALGSFLQIAQAEKESIPALLALAQAYVFLKQIPKARMQLKRLAKTPWM
LSEADDLEKSWLLLADIYCQGGKFDLATVLLRRCVQYNKSCYKAYEYLGFIMEKEQSYQD
AVTNYKLAWKYSHHT----SPAVGFRLAFNYV----KDKKFVEAIEICHDVSRQPWQGGL
ASGGEPCLILHTLL----SLFQVLREHPNYPKIREEILEKARRSLRP

------------------------------------------------------------
MSSNDSSLMAGIIYYSQEKYFHHVQQTAAVGLEKFSNDPVLKFFKAYGVLKEEHIQDAIS
DLESIR-HHPDVSLCSTMALIYAHKRCE--IIDREAIQELEYSLKEIRKTVSGTALYYAG
VFLWLIGHHDKAKEYIDRMLKISRGFR----EAYVLRGWVDLTSDKPHTAKKAIEYLEQG
IQDTKDVLGLMGKAMYFMMQQNYSEALEVVNQITVTSGSFLPALVLKMQLFLARQDWEQT
VEMGHRILEKDESNIDACQILAVHELAREGNMTTVSSLKTQK----ATNHVRNLIKALET
REPENPSLHLKKILVV-SRLCGSHQVILGLVCSFIERTFMA-TPSYIHVATELGYFFILK
NQVKEALLWYTEAMKLDKDGMAGLTGIILCHILEGHLEEAEHQLEF-----LKEVQKSL-
---GKSEVLIFLQALLTSKKHKGEQETTALLKEAVELHFSSMQGLPLGSEYFEKLDPYFL
VCIAKEYLLFCPKQPRLPGQIVSPLLKQVAVILNPVVKAAPALIDPLYLMAQVRYYS-EL
ENAQSILQRCLELDPASVDAHLLMCQIYLAQGNFGMCFHCLELGVSHNFQVR--------
-------DHPLYHLIKARALNKAGDYPEAIKTLKMVIKLPALKKEEGRKF-LGPSLQTSQ
RASILLELVEALRLNGELHEATKVMQDTINEFGGTPEENRITIANVDLVLSKGNVDVALN
MLRNISPKQSCYMEAREKMANVYLQTLRDRRLYIRCY------RELCEH----LPGPHTS
L

PF13432 // ENSGT00390000005979_1_Domain_5 (842, 900)

LLGDALMSILEPEKALEVYDEAYRQNPHDASLASRIGQAYVKAHQYTEAIEYYEAAQK

ENSGT00390000005979_1_Linker_5_6 (900, 907)

I
NGQDFL

PF13181 // ENSGT00390000005979_1_Domain_6 (907, 933)

CCDLAELLLKLKKINKAEKVLKQ-AL

ENSGT00390000005979_1_Linker_6_7 (933, 1022)

EHD--I-VQDIPSMMNDVKCLLLLA---
KVYESHKK---EAVIETLNKALDLQSRILKRVPLEQPEMIPSQKQLAASICIQF---AEH
Y

PF14559 // ENSGT00390000005979_1_Domain_7 (1022, 1089)

LAEKEYDKAVRSYKDVFSYLPT-DNKVMLELAQLYLLQGHLDLCEQHCAILLQTEQNHE
TASVLMADLMFRKQKHEAAINLYHQVLEKVPDNFLVLNKLIDLLRRSGKLE-DIPAFFEL
AKKVSSRVPLEPGFNYCRGIYCWHIGQPNEALKFLNKARKDSTWGQSAIYHMVQICLNPD
NEVVGGEAFENQGAES-NY-TEKKELEQQGVSTAEKLLREFYPNS-ASSQTQLRLLQGLC
RLATKEKANMEAALGSFIQIAQAEKDSVPALLALAQAYVFLKQIPKARMQLKRLAKAPWV
LSEAEDLEKSWLLLADIYCQGSKFDLALELLRRCVQYNKSCYKAYEYMGFIMEKEQSYKD
AVTNYKLAWKYSHHA----NPAIGFRLAFNYL----KDKKFVEAIEICHDV---------
-----------------------LREHPNYPKIREEILEKARRSLRP

------------------------------------------------------------
VAAVSSFIQAGIIYYSQEKYFHHVQQAAAVGLEKFSNDPVLKFFKAYGVLKEEHIQDAIS
DLESIR-HHPDVSLCSTMALIYAHKRCE--VVDREAIQELEYSLKEIRKTVSGTALYYAG
LFLWLIGRHDKAKEYIDRMLKISRGFR----EAYVLRGWVDLTSDKPHTAKKAIEYLEQG
IQDTKDVLGLMGKAMYFMMQQNYSEALEVVNQITVTSGSFLPALVLKMQLFLARQDWEQT
VEMGHRILEKDESNIDACQILTVHELAREGNMTTVSSLKTQK----ATNHVRNLIKALET
REPENPSLHLKKIIVV-SRLCGSHQVILGLVCSFIERTFVA-TSSYVHVATELGYLFILK
NQVKEALLWYSEAMKLDKDGMAGFTGIILCHILEGHLEEAEYQAPWGHWLLQDDADIGTE
TRSSLPQVLLFLQALLMSKKHKGEQETTALLKEAAELHFSSMQGIPLGSEYFEKLDPYFL
VCIAKEYLLFCPKQPRLPGQIVSPLLKQVAVILNPVVKAAPALIDPLYLMAQVRY

PF14559 // ENSGT00390000005979_1_Domain_2 (596, 634)

YSGEL
ENAQSILQRCLELDPASVDAHLLMCQIYLAQGNFGMCFHCLELGVSHNFQVR--------
-------DHPLYHLIKARALNKAGDYPEAIKTLKMVIKLPALKKKEGRKF-LGPSVQPSQ
RASILLELVEALRLNGELHEATKVMQDTIYEFGGTPEENRITIANVDLVLSKGNVDVALK
MLRNISPKQSCYMEAREKMANIYLQTLRDRCLYIRCY------RELCEH----LPGPHTN
L

PF13432 // ENSGT00390000005979_1_Domain_5 (842, 900)

LLGDALMSILEPEKALEVYDEAYRQNPHDASLASRIGQAYVKAHQYTEAIEYYEAAQK

ENSGT00390000005979_1_Linker_5_6 (900, 907)

I
NGQDFL

PF13181 // ENSGT00390000005979_1_Domain_6 (907, 933)

CYDLGELLLKLKKVNKAEKVLKQ-ALEHD--I-VQDIPSMMNDVKCLLLLA---
KVYKSRKK---EAVIETLNKALDLQSRILKRVPLEQPEMIPSQKQLAASICIQF---AEH
YLAEKEYDKAVQSYKDVFSYLPT-DNKVMLELAQLYLLQGHLDLCEQHCAIL-QTEQNHE
TTSVLMADLMFRKQKHEAAINLYHQVLEKAPDNFLVLNKLIDLLRRSGKLE-DIPAFFEL
ANKVSSRVPLEPGFKYCRGIYCWHIGQPNEALKFLNKARKDSTWGQSAIYHMVQICLNPD
NEVVGGEAFENQGAES-NY-MEKKELEQQGVSTAEKLLREFYPHS-DSSQTQLRLLQGLC
RLATREKANMEAALGSFIQIAQAEKDSVPALLALAQAYVFLKQIPKARMQLKRLAKTPWV
LSEAEDLEKSWLLLADIYCQGSKFDLALELLRRCVQYNKSCYKAYEYMGFIMEKEQSYKD
AVTNYKLAWKTQ-------GLYSGFKLAFNYL----KDKKFVEAIEICHDV---------
-----------------------LREHPNYPKIREEILEKARRSLRP

------------------------------------------------------------
MSSNDSSLMAEIIYYSKEKYFRHVQQAAAVGLEKFNNDPVLQFFKAYGALREEHIQDAIG
SLESIR-NHPDVSLCSIMALIYAHKCCE--TIDREAIQELESSLKEVRKTASGTALYYAG
LFLWLMGRHDKAKEYIDRTLKVSSSSR----EGHVLRGWVDLSSDKPHTVKKAIRYLEHG
IRDTRDVLGLMGKVMYFTMLQNYSGALEVVNQITVTCGSFPPALVLKMQLFLARQDWEQT
VEMGHRILEKDQSNIDACQILAVHELAREGNMTMVSSFKTQKLNLETNPHVRNLIKALET
REPQNPSLHLKKILVV-SRLCGRHQGILQLVCSFIERTFMA-TSSDAHMATELGYLFILQ
DQVKEASLWYSKAMKLDESSVAALTGMIWCQILDGHLEEAEHQLEFLKEVQ---------
QSLGKSKVLVFLQALLASKKHRGEQEATTLLKEAAELHFSGMQALPMSSEYLERLDPTFL
VCIAKEYLVFCPKQPRSPGQIVSPLLKQVAAILNPVVKVAPALTEPLYVMAQVKYLSGEL
EHAQST

PF13431 // ENSGT00390000005979_1_Domain_2 (607, 637)

LQRCLELDPTSVDAYLLMAQIYLAQGNFAMCSHSLELGVSHNFQVGLQPLLALG
DPFCWPKDHPLYHFIKAKALNK---------------------TEENKKF-RGPCVRPSE
RVSILLELADALRMNGELHEATKVMQDAINEFSGTPEEMRITIANVDLALSKGNVDLALS
VLQSITPKQPCYMDAKEKMASIYLQTHKDARLYIGCY------RELCEH----LPGPHTS

PF13432 // ENSGT00390000005979_1_Domain_5 (841, 902)

LLLGNAFMNIQEPEKALEVYDEAYRKNPHDASLISRIGQAYVKTHQYTKAINYYEAAQKI
S

ENSGT00390000005979_1_Linker_5_6 (902, 906)

GQDF

PF13181 // ENSGT00390000005979_1_Domain_6 (906, 933)

VCCDLAELLLKLKKFNKAEKVLKQ-AL

ENSGT00390000005979_1_Linker_6_7 (933, 1022)

DHD--F-VKDIPSMMNDVKCLLLLA---
KVYKSHKK---EDVMETLNKAMDLQSRILKRVPLEQPEMIPSQKQLAASICIQF---GEY
Y

PF14559 // ENSGT00390000005979_1_Domain_7 (1022, 1088)

LAEKEYAKAVQSYKDALSYTPI-DNKVALELARLYLLQGQLDLCEQHCAGLLQTEKDHE
TAAVVMADLMFRRQKYEAAIDLYHQVLEKAPDNFPVLNKLIDLLRRSGKLE-DAPAFFEL
AKKMSSRVPLEPGFNYCRGIYCWHIGQPNEALKFLNKARKDRAWGQSATYHMVQICLNPD
NEIVGGEAFQNLVTES-NF-TSRKELEQHGVRTAEKLLREFYPHS-AGGHTQLRLLQSLC
LLATREKANVEVALSTFVEMAQAEKDSVPALLAMAQACSLLKQIPKARTQLKRLAKAPWA
LAEADDLE

PF13181 // ENSGT00390000005979_1_Domain_9 (1329, 1360)

RSWLLLADIYCQGGKFDLASELLQRCVKYNKSCCKAYEYMGFIMEREQSYKD
AATNYELAWKYSHYT----SPAIGFRLAFNYL----KDKRFVEAIEVCRD----------
----------------------VLREHPNYPKIREEILEKAQVSLRP

------------------------------------------------------------
MCSSDSSLLAGIIYYSQEKYFRHVQQAAAVGLQKFSNDPVLQFFKSYGVLREERVQDAIS
ELENIR-GHPDLSLCSVMALLYAHKCCE--IVDREAIQELETSLKEVREQANETALYYAG
LFLWLIGRHDKAREYVDHMLNASSSFRELHPQGYVLKGWVDLTSEKPHIVKKSIKYLEQG
MQSNKDVLGLMGKATYLMIQQNYSGALDMVNQISTASGSFLPALVLKMRLFLAQQDWEQT
METTHRILEKDESNIDACQILTVHELVREGNMTTA------------TDNVRNLIKALEM
REPQNPSLQLKKILVI-SRLCGRHRAILRLVSSFMERIFLA-MPSCAQVATELGYLFILQ
NQEKEAALWYSEAMKLGENSVAALTGTIWCHILKDELEEAEHQLEFLKEVQ---------
QSLGRSEVLVFLQALLASKKHKGEQEVTALLQEVVELHFSHLQGLPLSPEYLEKLDPPFL
VCIAKEYLQFCPKQPRAPGQLVSPLLKQAAVILSPVVRAAPALPDPLYVMGQVKYLSGEL
ENAQST

PF13431 // ENSGT00390000005979_1_Domain_2 (607, 637)

IQRCLELDPTSADAHLLLAQIYLAQGNFAMCSHCLELGVSHNFQVR--------
-------DHPLYHFIKARALSKSGDYQEAIKTLKMIMKLPTLKTEESRKI-RGPSVQPSE
RVSILLELVDALRLNGELHEATKVMQDTINEFSGTAEEIRITIANVDLALSKGNMDLALS
MLRNITPKQPCYTEAKEKMASIYLHSRKDTCLYIGCY------RDLCEH----LPGPHTS

PF13432 // ENSGT00390000005979_1_Domain_5 (841, 900)

LLLGDAFMNIQEPEKALEVYNEAYKKNPHDASLVSRIGQAYVKTHQYSKAINYYEAAQK

ENSGT00390000005979_1_Linker_5_6 (900, 907)

I
SGLDFL

PF13181 // ENSGT00390000005979_1_Domain_6 (907, 932)

CCDLAELLLKLKKFNKAEKVLKQ-A

ENSGT00390000005979_1_Linker_6_7 (932, 1008)

LGHD--V-VKDIPSMMNDVKCLLLLA---
KVYKSYKK---EEVLETLNKALNLQSRILKRVPLEQPEMLPSQKQLA

PF13181 // ENSGT00390000005979_1_Domain_7 (1008, 1043)

ASICMLF---GEF
YSAEKDYAKAVQSYRDALSYSP

ENSGT00390000005979_1_Linker_7_8 (1043, 1084)

T-DNKVVLELAHLSLLQGYLDLSEQHCVILLQTDQAHE
TAS

PF13432 // ENSGT00390000005979_1_Domain_8 (1084, 1141)

LMMADLMFRKQNYEAAINLYHQVLEKAPDNFSVLDKLIDLLRRSGKLD-EAPAFFQL
VKKMSSRVSMEPGFNYCRGIYCWHIGQPNQALKFLNKARKDITWGQRANYYMVHICLNPD
NEIMGGEAFENQLTNT------KKESEQQGVRTAEKLLRDFYPLS-VIGQTQQRLLQSLC
LLATREKANMEAALGAFLEIAQAEVRWVGL----GD-----------------LWAKQWM
TAASTQ------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------

------------------------------------------------------------
MSSSDSSLLAGIIYYSQEKYFRHVQRAAAVGLEKFSNDPVLQFFKAYGVLREERIQDAIN
ELENVR-GHPDLSLCSIIALLYAHRRCE--TLDREAIQELESELKEVHRLASETALYYAG
LFLWLIGRHDKAKEYVDHMLKVSSSSR----EGCVLKGWVDLTSEKPHLVKKSIKYLEQG
IQSNKDVLGLMGKATYLMMQQNYSGALDTVNQISLASGSFLPALILKMQLFLAQQDWEQM
IETVHRILEKDDSNIDACQILAVHQLMREGNVTTA------------TDHVRNLIKALER
REPQNPSLHLKKVLVI-CRLCGRHRAILQLVSNFMERIFLA-VPSCAQVATELGYLFILQ
NQEKEAALWYSKAMKLGENSMAALAGTIWCHILKDELEEAEHQLEFLKEVQ---------
QSLGRSEVLVFLQALLASKKHKGEQEVTALLQEAAELHFSNVQGLPLSPQYLEKLDPPFL
VCIAKEYLQFCPKQPRAPGQLVSPLLKQAALILNPVVKAAPALIDPLYVMGQVQYLSGEL
ENAQSTVQRCLELDPTSTDAHLLMAQIYLVQGNFAMCSHCLELGVSHNFQVR--------
-------DHPLYHLIKARALNKSGDYQEAIKTLKMIMKLPTLKAEEGRKT-RRPFVQPSE
RVSILLELVSALRLNGELHEATKVMQDAIIEFSGTTEEISITIANVDLALSKGNVDLALS
MLKDITSKQPCYMEAKEKMASIYLQNRKDTYLYIGCY------RELCEH----LPGPHTS

PF13432 // ENSGT00390000005979_1_Domain_5 (841, 904)

LLLGDAFMKIQEPEKALEVYNEAYKKNPHDASLVSRIGQAYVKTHQYSKAINYYEAAQKI
SGQ

ENSGT00390000005979_1_Linker_5_6 (904, 906)

DS

PF13181 // ENSGT00390000005979_1_Domain_6 (906, 933)

LCCDLAELLLKLKKFNKAEKVLKQ-AL

ENSGT00390000005979_1_Linker_6_7 (933, 1022)

EHD--F-VKDIPSMMNDVKCLLLLA---
KVYKSYKR---EEVSETLNKALNLQSRILKRVPLEQPEMLPSQKQLAASICMLF---GEF
Y

PF14559 // ENSGT00390000005979_1_Domain_7 (1022, 1089)

WAEKDYARAEQSYKEALSYSPI-DNKVVLELARLSLLQGYLDSCEQHCTVLLQTDQTHE
SASV-MADLMFRKQNYDAAFNLYHQVLEKAPDNFLVLDKLIDLLRRSGTLE-EAPAFFQS
AQKMSSRVPMEPGFNYCRGIYCWHIGQPNQALKFLNKARKDITWGQKANYYMVHICLNPD
NELVGGEAQG--------S-ATRKESEQQGIRTAEKLLRDFYPLS-ASGQTQLRLLQSLC
LLTTREKANVEAALGAFLEIAQAEKDSVPALLGMAQACVLLKQIPKARTQLKRLAKAPWT
LAEAEDLEKSWLLLADIYCSGGKFDLATELLRHCIQYNKSCYKAYEYMGFIMEKEQSYKD
AATSYELAWKYSHQA----NPAIGFRLAFNYL----KAKKFVEAIEVCHN----------
----------------------VLREHPSYPKIREEILEKAQKSLRP

------------------------------------------------------------
-----LASDAEIIYYSQEQYFNQVQQTAARGLEKFSGDPGLLFFKAYGLLREGCVADAIS
ELENMQ-NHPHLTLCSVMALLYAYRIHHAHATILPAIQDLESSLKELRRHANHAAFYYAG
IFLWLVGRHEKAREYIDHMLKASSNAREVPAT-------TRTSHGNPHGTQKGVP-----
---ILDLLGGRGEATYLMMHQNFSGALEATNQMAVASGGFLPALVLKMQLFLACHDWEQT
VEIGHRILEKDENNIDACQILAVHELAREGNAILA------------ANCVGNLIKALET
KEPRNWNLHLKKILPV-SRLCGRQQEVVHLVSSFLERVFTA-APTCGLAAT

PF13181 // ENSGT00390000005979_1_Domain_1 (412, 439)

ELGYLYLLQ
NQPKEARTWYDEATKLQE

ENSGT00390000005979_1_Linker_1_2 (439, 597)

DRMAVLTGNIWCHILQGQLEEAAQQLEFLKEVQ---------
QSLGKSEVLVFLQALLASKKPPGEQAAPALLREVVELHFSAMHTLPLSPEYFEKLDPLFL
VGVARELLRFCPKQPRPPGQVVSPLLTQVAMILSPVLKAAPAMMDALLVMAEVNFL

PF13432 // ENSGT00390000005979_1_Domain_2 (597, 635)

SGDL
ETAQSSLQRCLELDPAWVDAHLLLAQVHLAQGNFAMCAHCLELGVSHNFQVR--------
-------DYPLYHFIKARALNKSGEHAEAVKTLKMIAALPGAKGEEGPRSRRAPPLHPGE
RASVLLELVDALRLNGELHEATKVMQDAVHQFRGTPEESRVTLANVDLALSKGAVDAALT
MLRGVGPAQPGYADARQKMADIYLHTRRDPRLYINCY------RELCEH----LPGPHTS

PF13432 // ENSGT00390000005979_1_Domain_5 (841, 902)

LLLGDAYMNIQEPEKALEVYEEAYKKNPHDAGLVSRIGQAYVKTHQYSKAINYYEAAQKM
S

ENSGT00390000005979_1_Linker_5_6 (902, 907)

GQDFL

PF13181 // ENSGT00390000005979_1_Domain_6 (907, 934)

CCDLAELLLRLKKFSKAEKVLKQ-ALE

ENSGT00390000005979_1_Linker_6_7 (934, 1023)

RE-----SGLAPMMDQVKCWLMLA---
KVYKSHKK---EEVAETLGKALDVQTKVLKRAPMEQPEIITTQKQLASSICIQC---GEH
YA

PF14559 // ENSGT00390000005979_1_Domain_7 (1023, 1080)

AEEDYAKAVRAYKDALCYSPT-DNKVVLELARLHLLQGNLDLCEDQCSMLLQTSQDDA
STSVMLADLMFRKQNYEAAIGHYRQVLEKCPDDF

PF01535 // ENSGT00390000005979_1_Domain_8 (1115, 1140)

VVFNKLIDLLRRSGRLE-EAPTFFE

ENSGT00390000005979_1_Linker_8_9 (1140, 1329)

L
AKKGSSRVVLEPGFNYCKGIYYWHVGRPNEALKFLNKARKDTTWGQEATDYMVRICLNPD
DEILGGEVFENTGAES-K-----AGSRPQGLRTAERLLQEFPPPS-DPGPARLRLLRGLC
LLHSGARAQVEAALVAFVELAQAEKENAAALLALAQAYTLLQQIPKARTQLKRLARAVWT
PGEADALE

PF13181 // ENSGT00390000005979_1_Domain_9 (1329, 1360)

RAWLLLAHLHCTAGKFDLAVELLRRCVRYNKSCAKAYEYMGFIMEKEQSYKD
AATNYELAWKYSHHS----NPAIGFKLAFNYL----KDKKFVEAIEICHH----------
----------------------VLLQYPNYPKIREEILEKAQGSLRP

------------------------------------------------------------
MSSDDSSLMASIIYYSQEKYFHHVLQAANVGLERYSSDPVLQFFRAYGILGEDHIHDAIS
ELEGIQ-SHPDTSLCAVIALLSAHKCCD--TIDIEAVQELESSLKEIRRSASSTALYYAS
LFLWFMGHHDKAREYVDHMLKVSNGSK----EGYVLKGWVDLTSSKPHVVKKSIKYLEQG
TQDTKDVLGLMGKATYFMTQQNFSGALEVANQVTLACSNFLPALVLKMKLFLARQDWDQT
IETGQRILEKDENNIDAWQILAVHELVKEGNTDRA------------ADRVRNLIKALET
GEPHNPNLHLKKILVI-SRLSGRHQVVHRLVSGFLERVFMA-TPSCALVATELGYLFILH
QQVKEACLWYKEAMKLEENRLAALAGSIWCQILQGQLEEAAHQLEFLKEVQ---------
QSLGKSELLVFLQALVAAKKQRLEQEATALLKEAVELHFSSMQGLALSPEYFEKLDPLFL
VCIAKEYLHFCPKQPRSPGQLVSPLLKQVAMILSPVVKVAPAMMEPLYVTAQVKFLSGEL
ENAQSTLQRCLELDPTFVDAHLLMSQIYLAQGNFAMCSHCLELGVSHNFQVR--------
-------DHPLYHFIKARALNKTGDYAEAIKTLKMIIKVPTSKAEEGRKS-RSPSVRPSE
RASILLELVEALRLNGELHEATKIMQDAINEFSGTPEEMRITVANVDLALSKGNVDLALN
MLRGITPKQPCYTEAKEKMASIYLHTRKDVRLYIGCY------VELCEH----LPGPHSS

PF13432 // ENSGT00390000005979_1_Domain_5 (841, 902)

LLLGDAFMNIQEPEKALEVYDEAYRKNPHDASLVSRIGQAYVKTHQYAKAINYYEAAQKI
S

ENSGT00390000005979_1_Linker_5_6 (902, 907)

GQDFL

PF13181 // ENSGT00390000005979_1_Domain_6 (907, 935)

CCELAELLLKLKKYHKAEKVLKQ-ALER

ENSGT00390000005979_1_Linker_6_7 (935, 1022)

D--SGVKDIPSMINEVKCLLLLA---
KVYKSHKK---EEVMETLNLALDLQSRILKRVPLEQSEMIPFQNQLAASICIQI---GEH
H

PF14559 // ENSGT00390000005979_1_Domain_7 (1022, 1088)

LAEKDYNSAVKSYKDALAYSPT-DSKVVLELAHLYLLLGQLDLCEQRCAPLLEMEQTHE
RAAVMLADLMFRRQNYETAINLYHQVLEKAPDNFLVLNKLVDLLRRSGKLE-EAPAFFEL
AKKVSSRVPLEPGFNYCQGIYFWHIGQPNEALRFLNKARKDSTWGQLATCYMVQICLNPD
NEIVGGEAFESLVGDS-NS-ASRKESQQHGVRTAEKLLREFYPHS-ESGQTQLRLLQNLC
LLATREKANVEAALGAFIEMAQAEKDSIPALLAMAQAYILLKQVPKARTQLKRLAKVPWM
VDEAEDLE

PF13181 // ENSGT00390000005979_1_Domain_9 (1329, 1360)

KSWLLLADIYCQGGKFDLALELLRRCLQYNKSCCRAYEYMGFIMEKEQSYKD
AATNYELAWKYSHQA----NPAIGFKLAFNYL----KDKKFVDAIEVCHS----------
----------------------VLTEHPKYPKIREEILEKAQGSLRP

------------------------------------------------------------
MSSDDSSLMASIIYYSQEKYFHHVLQAANVGLERYSSDPVLQFFRAYGVLGEDHIHDAIS
ELEGIQ-SHPDTSLCAVIALLSAHKCCD--TIDIEAVQELESSLKEIRRSASSTALYYAS
LFLWFMGHHDKAREYVDHMLKVSSGSK----EGYVLKGWVDLTSSKPHVVKKSIKYLEQG
TQDTKDVLGLMGKATYFMTQQNFSGALEVVNQVTLACSNFLPALVLKMKLFLARQDWDQT
IETGQRILEKDENNIDAWQILAVHELVKEGNTDRA------------ADRVRNLIKALET
GEPHNPNLHLKKILVI-SRLGEKVPASPMQNH---TSCDLP-PPGSNLTDSPPGPLTSKV
Q-TDQVAME-----FVFCKAFTPKQGSIWCQILQGQLEEAAHQLEFLKEVQ---------
QSLGKSELLVFLQALVAAKKQRLEQEATELLKEAVELHFSSMQGLALSPEYFEKLDPLFL
VCIAKEYLHFCPKQPRSPGQLVSPLLKQVTMILSPVVKVAPAMMEPLYVTAQVKFLSGEL
ENAQSTLQRCLELDPTFVDAHLLMSQIHLAQGNFAMCSHCLELGVSHNFQVR--------
-------DHPLYHFIKARALNKTGDYAEAIKTLKMIIKVPTSKAEEGRKS-RSPSVRPSE
RASILLELVEALRLNGELHEATKIMQDAINEFSGTPEEMRITVANVDLALSKGNVDLALN
MLRGITPKQPCYTEAKEKMASIYLHTRKDVRLYIGCY------MELCEH----LPGPHSS

PF13432 // ENSGT00390000005979_1_Domain_5 (841, 902)

LLLGDAFMNIQEPEKALEVYDEAYRKNPHDASLVSRIGQAYVKTHQYAKAINYYEAAQKI
S

ENSGT00390000005979_1_Linker_5_6 (902, 907)

GQDFL

PF13181 // ENSGT00390000005979_1_Domain_6 (907, 935)

CCELAELLLKLKKYHKAEKVLKQ-ALER

ENSGT00390000005979_1_Linker_6_7 (935, 1022)

D--SGVKDIPSMINEVKCLLLLA---
KVYKSHKK---EEVMETLNLALDLQSRILKRVPLEQSEMIPFQNQLAASICIQI---GEH
H

PF14559 // ENSGT00390000005979_1_Domain_7 (1022, 1088)

LAEKDYDSAVKSYKDALAYSPT-DSKVVLELAQLYLLQGQLDLCEQRCAPLLEMEQTHE
RAAVMLADLMFRRQNYETAINLYHQVLEKAPDNFLVLNKLVDLLRRSGKLE-EAPAFFEL
AKKVSSRVPLEPGFNYCQGIYFWHIGQPNEALRFLNKARKDSIWGQRATCYMVQICLNPD
NEIVGGEAFESLVGDS-NS-ASRKESQQHGVRTAEKLLREFYPHS-ESGQTQLRLLQNLC
LLATREKANVEVALGAFIEMAQAEKDSIPALLAMAQAYILLKQVPKARTQLKRLAKVPWM
VDEAEDLE

PF13181 // ENSGT00390000005979_1_Domain_9 (1329, 1360)

KSWLLLADIYCQGGKFDLALELLRRCLQYNKSCCRAYEYMGFIMEKEQSYKD
AATNYELAWKYSHRA----NPAIGFKLAFNYL----KDKKFVDAIEVCHS----------
----------------------VLTEHPKYPKIREEILEKAQGSLRP

------------------------------------------------------------
MNSNDSSLMAGIIYYSQEKYFHHVQQTAAVGLEKFSNDPVLKFFKAYGVLKEEHIQDAIS
DLESIR-HHPDVSLCSTMALIYAHKRCE--IIDREAIQELEYSLKEIRKTVSGTALYYAG
VFLWLIGHHDKAKEYIDRMLKISRGFR----EAYVLRGWVDLTSDKPHSAKKAIEYLEQG
IQDTKDVLGLMGKAMYFMMQQNYSEALEVVNQITVTSGSFLPALVLKMQLFLARQDWEQT
VEMGHRILEKDESNIDACQILAVHELAREGNMTTVSSLKTQK----ATNHVRNLIKALET
REPENPNLHLKKILVV-SRLCGSHQVILGLVCSFIERTFMA-TPSYIHVATELGYFFILK
NQVKEALLWYTEAMKLDKDGMAGLTGIILCHILEGHLEEAEHQLEF-----LKEVQKSL-
---GKSEVLIFLQALLTSRKHKGEQETTALLKKAVELHFSSMQGLPLGSEYFEKLDPYFL
VCIAKEYLLFCPKQPRLPGQIVSPLLKQVAVILNPVVKAAPALIDPLYLMAQVRY

PF14559 // ENSGT00390000005979_1_Domain_2 (596, 634)

YSGEL
ENAQSILQRCLELDPASVDAHLLMCQIYLAQGNFGMCFHCLELGVSHNFQVR--------
-------DHPLYHLIKARALNKAGDYPEAIKTLKMVIKSPALKKEEGRKF-LGPSLQTSQ
RASILLELVEALRLNGELHEATKVMQDTINEFGGTPEENRITIANVDLVLSKGNVDVALN
MLRNISPKQSCYMEAREKMASVYLQTLRDRRLYIRCY------RELCEH----LPGPHTS
L

PF13432 // ENSGT00390000005979_1_Domain_5 (842, 900)

LLGDALMSILEPEKALEVYDEAYRQNPHDASLASRIGQAYVKANQYTEAIEYYEAAQK

ENSGT00390000005979_1_Linker_5_6 (900, 907)

I
NGQDFL

PF13181 // ENSGT00390000005979_1_Domain_6 (907, 933)

CCDLAELLLKLKKINKAEKVLKQ-AL

ENSGT00390000005979_1_Linker_6_7 (933, 1022)

EHD--I-VQDIPSMMNDVKCLLLLA---
KVYESHKK---EAVIETLNKALDLQSRILKRVPLEQPEMIPSQKQLAASICIQF---AEH
Y

PF14559 // ENSGT00390000005979_1_Domain_7 (1022, 1089)

LAEKEYDKAVRSYKDVFSYLPT-DNKVMLELAQLYLLQGHLDLCEQHCAILLQTEQNHE
TASVLMADLMFRKQKHEAAINLYHQVLEKVPDNFLVLNKLIDLLRRSGKLE-DIPAFFEL
AKKVSSRVPLEPGFNYCRGIYCWLIGQPNEALKFLNKARKDSTWGQSAIYHMVQICLNPD
NEVVGGEAFENQGAES-NY-TEKKELEQQGVSTAEKLLREFYPNS-ASSQTQLRLLQGLC
RLATKEKANMEAALGSLIQIAQAEKDSVPALLALAQAYVFLKQIPKARMQLKRLAKAPWV
LSEAEDLEKSWLLLADIYCQGSKFDLALELLRRCVQYNKSCYKAYEYMGFIMEKEQSYKD
AATNYKLAWKYSHHDPHHDPRTQGFRLAFNYL----KDKKSVEAIEICHDV---------
-----------------------LREHPNYPKIREEILEKARRSLRP

------------------------------------------------------------
MSSNDSFLMAEIIYYSQEKYFRHLRQAAATGLEHFSGDPVLQFFKAYGELREERIQEAIS
DLESIR-SHPDVSLCSVMALLYAHKRCE--TVDREAVQELESSLKEVRRTAG

PF00515 // ENSGT00390000005979_1_Domain_0 (173, 206)

GTALYHAG
LFLWLLGRHDKAKDYVDHALRVSSGSR----EGYVLKGWLDLTADKPHAVKRSIKYLEQG
IQDTRDTLGMMGKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXILERDEGNIDAHQLLAVHELAREGDGTKVSSVKA------AAEHVRNLIKALET
REPQNPSLHLKKILVV-SKLCGRHHAVQQLVSGFMERTFLT-TPSYSQVAVELGRLCILQ
DEVKEASGWYSEAMKLDGTSIAALTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----
XXXXXXXXXXXXXX-XXXXXXXXXXXXXXX-X-XXXXXXXXXXXXXXXXXXXX-XXXXXX
XXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----XXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--------
-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRAEEGRKL-RGPSVRPSE
RVSILLELADALRLNGELHEATKVMQDTINEFSGTPEEVRITIANVDLALSKGDVDMALG
MLRRVTPTQPCYTEAKEKMASIYLQTRRDTRLYIGCY------RELCEN----LPG

PF00515 // ENSGT00390000005979_1_Domain_4 (837, 870)

PHTS
LLLGDAFMHIQEPEKALEVYDEAYRKNPHDASLVSRIGQAYVKTHQYSKAINYYEAAQKM
SGQD

PF00515 // ENSGT00390000005979_1_Domain_6 (905, 941)

ALCCDLAELLLKLNKVAKAEKVLKQ-ALEHD---PV

ENSGT00390000005979_1_Linker_6_7 (941, 1008)

KDIPSMMKDVRCLLLLA---
KVYGSHRR---EDVPETLHKALDLQSRILKRVSLEQPEMVPSQKQLA

PF00515 // ENSGT00390000005979_1_Domain_7 (1008, 1044)

ASICVQF---GEH
YLAEKEYPKAVRAYKDAQSYSPT

ENSGT00390000005979_1_Linker_7_8 (1044, 1080)

DDK--VVELAHLY-LQGHLDLCEQHCATLLQTEQNL

PF00515 // ENSGT00390000005979_1_Domain_8 (1080, 1113)

E
TASVLMADLMFRKQNYEAAVNLYLQVLEKAPGNFLVLNKLIDLLRRSGRLE-EAPAAFEQ
AQKASCRVLMEPGFNYCRGVYCWHLGQPNEALRSLNRARRDSTWGQMATCFMVQICLNPD
NEVVGGEALHSVVAES-SS-PDKSDLGQHGVRTAEKLLRELYPTS-ASGQAQLRLLQGHC
LMATRE-ANVEAALGIFIEMARAERDSVSALLAMAQAYALLKQVPKARTQLKRQAKAPWT
LDQAEDLEKSWLLLADIYCQGGKFDLASELLGRCVQYNK---------------------
------------------------------------------------------------
-----------------------------------------------

------------------------------------------------------------
MSSDDSSLMASIIYYSQEKYFHHVQQAASVGLERYSNDPVLQFFKAYGVLGEDHIHDAIS
ELESIQ-SHPDMSLCSVIALLYAHKCCD--TIDGEAVQELESSLKEIRKTASGTALYYAS
LFLWLIGHHDKAREYVDHMLKVCHGSK----EGYVLKGWVDLTSNKPHVVKKSIKYLEQG
TQDTKDVLGLMGKATYYLIQQNFSGALEVVNQVTMASGNFLPALVLKMRLFLARQDWDQT
VETGHRILEKDESSIDAWQILTVHELAREGNTATA------------TNHVKNLIKALET
GEPQNPSLHLKKILVV-SRLCGRHQAVQRLVSGFLERIFMS-TPTCALVATELGYLFILQ
QQVKEACLWYKEAMKLEENRLAALAGSIWCQILQGQLEEAAHQLEFLKEVQ---------
QSLGKSEVLVFLQALVASKKQKPEQEATALLKEAVELHFSSMQGLALSPEYFEKLDPLFL
VCIAKEYLHFCPKQPRSPGQLVSPLLKQVAMILSPVVKVAPAMMDPLFVTAQVKFLSGEL
ENSQSTLQRCLELDPTFVDAHLLMSQIYLAQGNFAMCSHCLELGVSHNFQVR--------
-------DYPLYHFIKARALNKTGDYAEAIKTLKMIVKLPTTKAEESRKS-RGPSVRPSE
RASILLELVEALRLNGELHEATKIMQDAINEFSGTPEEMRITVANVDLALSKGNVDLALS
MLRGITPKQPCYTEAKEKMASIYLHTRKDMRLYIGCY------MELCEH----LPGPHSS

PF13432 // ENSGT00390000005979_1_Domain_5 (841, 902)

LLLGDAFMNIQEPEKALEVYDEAYRKNPHDASLVSRIGQAYMKTHQYAKAINYYEAAQKI
S

ENSGT00390000005979_1_Linker_5_6 (902, 907)

GQDFL

PF13181 // ENSGT00390000005979_1_Domain_6 (907, 935)

CCELAELLLKLKKYHKAEKVLKQ-ALER

ENSGT00390000005979_1_Linker_6_7 (935, 1024)

D--SGVKDIPSLMNEVKCLLLLA---
KVYKNHKK---EDVVGTLNQALDLQSRILKRVPLEQPEMLPFQKQLAASICIQT---GEH
YVT

PF14559 // ENSGT00390000005979_1_Domain_7 (1024, 1088)

EKDYDNAVKSYKDALSYSPT-DNKVALELAQLYLLQGQLDLCEQRCGPLLQMEQTQE
RAAVMLADLMFRKQNYEEAISLYRQVLEKAPDNFLVLNKLIDLLRRSGKLE-EAPAFFEL
AKKVSSRVPLEPGFNYCQGLYCWHIGQPNEALKFLNKARKDSTWGQIATCYMVQICLNPD
NEIVGGETFESLMADS-NS-TSRKESQQHGVRTAEKLLREFYPHS-DSRQTQLRLLQSLC
LLATREKANVEAALGSFIEMAQAEKDSIPVLLAMAQAYMLLKQVPKARTQLKRLAKVPWT
LDEAEDLE

PF13181 // ENSGT00390000005979_1_Domain_9 (1329, 1360)

KSWLLLADIYCQGGKFDLASELLRRCLQYNKSCCKAYEYMGFIMEKEQSYKD
AATNYELAWKYSHQA----SPAIGFKLAFNYL----KDKKFVDAIEVCHS----------
----------------------VLTEYPNYPKIREEILEKAQGSLRP

------------------------------------------------------------
---------AGIIFYSQERYFRHVQQAAAMGLEKFSNDPVLQFFKAYGVLREERIQDAIS
DLEGIS-HHPHVSLCSTMALIYAHKSCE--TIDQEALQELESSLKDLRKTASETALYYGG
LFLWLMDRHDKAREYADRMLKLANSSR----EGYVLKGWVDLTSDKPHHVKKSIKYLELG
LQDNRDALGLLGKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXILEKDENCIDARQILAVYELAREGNMSTVSSSRTQK----AADHVRNLIKALEM
TEPLNPGLHLKKILVV-SRLCGQHQAVLQLVCSFMERTFMA-TPSS

PF00515 // ENSGT00390000005979_1_Domain_1 (407, 440)

ARVATELGYLFILH
SQVKEASSWYMKAMKLDENSVAALTGVIWCQILQGHLEEAANQLEFLREVQ---------
QSLGKSKVLVFLQALLASKKHKGEQEATALLTEAVELHFSHMQGLDLGCEYFEKLDPLFL
ILIAKKYLFFCPKQPRLPGQVVSPLLKQVAVILNPVVKALPALISPLYVMAQVKYLSXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXX--------
-------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTEEGRKS-RRHSFQPSE
RGSILLALDGASGLRGELHEATKVVQDAINEFGGTPEETRLTLANADLALSKGNADLALS
VLRGISPKQPCYTEAKEKMASIYLQTRKDTRLYIGCY------RELCEH----LPG

PF07719 // ENSGT00390000005979_1_Domain_4 (837, 870)

PHTS
LLLGDALMNIQEPEKALEVYDEAYRKNPHDASLVSRIGQAYVKTHQYAKAINYYEAAQKI
SGQDF

PF00515 // ENSGT00390000005979_1_Domain_6 (906, 941)

LCCHLAELLLKLKKFSKAEKVLKQ-ALDHD---VADDIPSMTNDVKCLLLLA---
KVYKSHKK---EDVIETLNKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----XX
XXXXXXXXXXXXXXXXXXXXXXXXXXXVVLALARLDLLLGHLDLCEQHCAILLQTEQNHE
TASMXXXXXXXXXXXXXAAVSLYHRILEKAPDNFAVLDKLIDLLRRSGRLE-DAPAFFEL
AKKTSSRVPLEPGFNYCRGLYCWHTGQPNEALTFLNKARKDSTWGQSATSHMVQICLNPD
NEVLGGGAFESLVAEG-NS---QQRVEQHGVRTEK--LLDFYPHSXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---XXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTGASCCKAYEYMGLIMEKEQSYKD
AASNYELAWKHSHHA----S

PF00515 // ENSGT00390000005979_1_Domain_10 (1401, 1470)

PSIGFKLAFNYL----KDKKFVEAIEVCHN----------
----------------------VLREHPNYPKIREEILEKAQGSLRP

------------------------------------------------------------
MSNNDSSLMAGIIYYCQERYFRHMQQAAAVGLEKFNNDPVLQFFKAYGVLMEERIQDAIS
SLESIR-NHPDVSLCSTMALIYAHKCCE--TIDREAIQELESSLKEIRKTASGTALYHAG
LFLWLIGCHDKAKEYTDRLLKVSSSSR----EGCMLRGWVDLSSDKPHTVKKSIKYLEQG
MQDTKDVLGLMGKAKYFMMLQNYSGALEVVNQITVTSGSFLPALVLKMQLFLARQDWEQT
VETGHRILEKDESNIDACQILAVHELAREGNITTA------------AEHVRNLINALET
REPQNPSLHLKKILVV-SRLCGRHQVILRLVCSFIERTFRA-TSSYAHVATELGYLFILR
DQVKEASLWYSEAMKLSKSGM-AMTGITWCQILEGHLEEAEHQLEFLKEVQ---------
QSLGKSEVLVFLQALLASRKHKGEQEVTALLKEAAELHFSSMRALPLGSEYLERLDPLFL
VCIAKEYLLFCPKQPRSPGQIVSPLLKQVTAILNPVVKVAPALIDP

PF13181 // ENSGT00390000005979_1_Domain_2 (587, 616)

LYVMAQVKYLSGEL
ENAQSTLQRCLELDPTSVDAHLLVSQIYLAQGNFAMCSHCLELGISHNFQVR--------
-------DHPLYHFIKARALNKSGDYPEAIKALKMIINVPTLKMEENKKF-RGPSVQPSE
RVSILLELVDALRMNGELHEATKIMQDAINEFSGTPEEIRITIANVDLVLSKGNVDLALS
MLRNITPKQPYYMEAKEKMASIYLQTHKDMRLYIGCY------RELCEH----LPGPHTS

PF13432 // ENSGT00390000005979_1_Domain_5 (841, 902)

LLLGDAFMNIQEPEKALEVYDEAYRKNPHDASLVSRIGQAYVKTHQYTKAINYYEAAQKI
SGQDFLCCDLAELFLKLKKFSKAEKVLKQ-ALDHD--F-VKDIPSMMNDVKCLLLLA---
KVYKSHKK---EDVMETLNKAMDLQSRILKRVPLEQPEMIPSQKQLAASICIHF---GEY
Y

PF14559 // ENSGT00390000005979_1_Domain_7 (1022, 1085)

LAEKEYAKAVRSYKDALSYSPT-DNKVVLELAHLYLLQGHLDLCEQHCDILLQTEKNHE
MASVMMADLMFRKQKYEAAINLYHQVLEKAPDNFPVLNKLIDLLRRSGKLE-DAPAFFEL
AKKMSSRVPLEPGFNYCRGIYCWHIGQPNEALKFLNKARKDNTWGQSATYCMVQICLNPD
NEIVGGEAFESLVPES-NS-LERKESERHGVRTAEKLLREFYPQS-ASGQTQLRLLQSLC
LLATREKANVEAALGTFIDMAQAEKDSVPALLAMAQAYSLLKQVPKARTQLKRLAKAPWA
LAEADDLE

PF13181 // ENSGT00390000005979_1_Domain_9 (1329, 1360)

KSWLLLADIYCQGGKFDLASELLRRCVQYNKSCCKAYEYMGFIMEREQSYKD
AATNYELAWKYSHHA----NPAIGFKLAFNYL----KDKRFVEAIEVCHSVSPRQQQGVL
GAVAGSPAVCSTPFLLSVPLSQVLREHPNYPKIREEILKKAQGSLRP

------------------------------------------------------------
MSSNDSSLMAGIIYYSQEKYFHHVQQAAAVGLEKFSNDPVLKFFKAYGVLKEEHIQDAIS
DLESIR-HHPDVSLCSTMALIYAHKRCE--IIDREAIQELEYSLKEIRKTVSGTALYYAG
LFLWLIGRHDKAKEYIDRMLKISRGFR----EAYVLRGWVDLTSDKPHTAKKAIEYLEQG
IQDTKDVLGLMGKAMYFMMQQNYSEALEVVNQITVTSGSFLPALVLKMQLFLARQDWEQT
VEMGHRILEKDESNIDACQILTVHELAREGNMTTVSSLKTQK----ATNHVRNLIKALET
REPENPSLHLKKIIVV-SRLCGSHQVILGLVCSFIERTFMA-TPSYVHVATELGYLFILK
NQVKEALLWYSEAMKLDKDGMAGLTGIILCHILEGHLEEAEYRLEF-----LKEVQKSL-
---GKSEVLIFLQALLMSRKHKGEEETTALLKEAVELHFSSMQGIPLGSEYFEKLDPYFL
VCIAKEYLLFCPKQPRLPGQIVSPLLKQVAVILNPVVKAAPALIDPLYLMAQVRYYS-EL
ENAQSILQRCLELDPASVDAHLLMCQIYLAQGNFGMCFHCLELGVSHNFQVR--------
-------DHPLYHLIKARALNKAGDYPEAIKTLKMVIKLPALKKEEGRKF-LRPSVQPSQ
RASILLELVEALRLNGELHEATKVMQDTINEFGGTPEENRITIANVDLVLSKGNVDVALN
MLRNILPKQSCYMEAREKMANIYLQTLRDRRLYIRCY------RELCEH----LPGPHTS
L

PF13432 // ENSGT00390000005979_1_Domain_5 (842, 900)

LLGDALMSILEPEKALEVYDEAYRQNPHDASLASRIGHAYVKAHQYTEAIEYYEAAQK

ENSGT00390000005979_1_Linker_5_6 (900, 907)

I
NGQDFL

PF13181 // ENSGT00390000005979_1_Domain_6 (907, 933)

CCDLGKLLLKLKKVNKAEKVLKQ-AL

ENSGT00390000005979_1_Linker_6_7 (933, 1022)

EHD--I-VQDIPSMMNDVKCLLLLA---
KVYKSHKK---EAVIETLNKALDLQSRILKRVPLEQPEMIPSQKQLAASICIQF---AEH
Y

PF14559 // ENSGT00390000005979_1_Domain_7 (1022, 1089)

LAEKEYDKAVQSYKDVFSYLPT-DNKVMLELAQLYLLQGHLDLCEQHCAILLQTEQNHE
TASVLMADLMFRKQKHEAAINLYHQVLEKAPDNFLVLHKLIDLLRRSGKLE-DIPAFFEL
AKKVSSRVPLEPGFNYCRGIYCWHIGQPNEALKFLNKARKDSTWGQSAIYHMVQICLNPD
NEVVGGEAFENQGAES-NY-MEKKELEQQGVSTAEKLLREFYPHS-DSSQTQLRLLQGLC
RLATREKANMEAALGSFIQIAQAEKDSVPALLALAQAYVFLKQIPKARMQLKRLAKTPWV
LSEAEDLEKSWLLLADIYCQGSKFDLALELLRRCVQYNKSCYKAYEYMGFIMEKEQSYKD
AVTNYKLAWKYSHHA----NPAIGFKLAFNYL----KDKKFVEAIEICNDV---------
-----------------------LREHPDYPKIREEILEKARRSLRP

------------------------------------------------------------
MSSNDSSLMAGIIYYSQEKYFHHVQQAAAVGLEKFSNDPVLKFFKAYGVLKEEHIQDAIS
DLESIR-HHPDVSLCSTMALIYAHKRCE--IIDREAIQELEYSLKEIGKTVSGTALYYAG
LFVWLIGCHDKAKEYIDRMLKISRGFR----EAYVLRGWVDLTSDKPHTAKKAIEYLEQG
IQDTKDVLGLMGKAMYFMMQQNYSEALEVVNQITVTSGSFLPALVLKMQLFLARQDWEQT
VEMGHRILEKDESNIDACQILTVHELAREGNMTTVSSLKTQK----ATNHVRNLIKALET
REPENPSLHLKKIIVV-SRLCGSHQVILGLVCSFIERTFMA-TPSYVHVATELGYLFILK
NQVKEALLWYSEAMKLDKDGMAGLTGIILCHILEGHLEEAEYRLEF-----LKEADIGTE
TRSSLPQVLIFLQALLMSKKHKGEEETTALLKEAVELHFSSMQGIPLGSEYFEKLDPYFL
VCIAKEYLLFCPKQPRLPGQIVSPLLKQVAVILNPVVKAAPALIDPLYLMAQVRY

PF14559 // ENSGT00390000005979_1_Domain_2 (596, 634)

YSGEL
ENAQSILQRCLELDPASVDAHLLMCQIYLAQGNFGMCFHCLELGVSHNFQVR--------
-------DHPLYHLIKARALNKAGDYPEAIKTLKMVIKLPALKKEEGRKF-LRPSVQPSQ
RASILLELVEALRLNGELHEATKVMQDTINEFGGTREENRITIANVDLVLSKGNVDVALN
MLRNILPKQSCYMEAREKMANIYLQTLRDRRLYIRCY------RELCEH----LPGPHTS
L

PF13432 // ENSGT00390000005979_1_Domain_5 (842, 900)

LLGDALMSILEPEKALEVYDEAYRQNPHDASLASRIGQAYVKAHQYTEAIEYYEAAQK

ENSGT00390000005979_1_Linker_5_6 (900, 907)

I
NGQDFL

PF13181 // ENSGT00390000005979_1_Domain_6 (907, 933)

CCDLGKLLLKLKKVNKAEKVLKQ-AL

ENSGT00390000005979_1_Linker_6_7 (933, 1022)

EHD--I-VQDIPSMMNDVKCLLLLA---
KVYKSHKK---EAVIETLNKALDLQSRILKRVPLEQPEMIPSQKQLAASICIQF---AEH
Y

PF14559 // ENSGT00390000005979_1_Domain_7 (1022, 1089)

LAAKEYDKAVQSYKDVFSYLPT-DNKVMLELAQLYLLQGHLDLCEQHCAILLQTEQNHE
TASVLMADLMFRKQKHEAAINLYHQVLEKAPDNFLLLNKLIDLLRRSGKLK-DIPAFFEL
AKKVSSRVPLEPGFNYCRGIYCWHIGQPNEALKFLNKARKDGTWGQSAIYHMVQICLNPD
NEVVGGEAFENQGAES-NY-MEKKELEQQGVSTAEKLLREFYPHS-DSSQTQLRLLQGLC
RLATREKANMEAALGSFIQIAQAEKDSIPALLALAQAYVFLKQIPKARMQLKRLAKTPWV
LSEAEDLEKSWLLLADIYCQGSKFDLALELLRRCVQYNKSCYKAYEYMGFIMEKEQSYKD
AVTNYKLAWKYSHHGPHHDPRTQGFKLAFNYL----KDKKFVEAIEICNDV---------
-----------------------LREHPDYPKIREEILEKARRSLRP

------------------------------------------------------------
MSSNDSCLMAGIIYYSQEKYFHHVQQTAAVGLEKFSNDPVLKFFKAYGVLKEEHIQDAIS
DLESIR-HHPDVSLCSTMALIYAHKRCE--IIDREAIQELEYSLKEIRKTVSGTALYYAG
VFLWLIGHHDKAKEYIDRMLKISRGFR----EAYVLRGWVDLTSDKPHTAKKAIEYLEQG
IQDTKDVLGLMGKAMYFMMQQNYSEALEVVNQITVTSGSFLPALVLKMQLFLARQDWEQT
VEMGHRILEKDESNIDACQILAVHELAREGNMTTVSSLKTQK----ATNHVRNLIKALET
REPENPSLHLKKILVV-SRLCGSHQVILGLVCSFIERTFMA-TPSYIHVATELGYFFILK
NQVKEALLWYTEAMKLDKDGMAGLTGIILCHILEGHLEEAEHQLEF-----LKEVQKSL-
---GKSEVLIFLQALLTSKKHKGEQETTALLKEAVELHFSSMQGLPLGSEYFEKLDPYFL
VCIAKEYLLFCPKQPRLPGQIVSPLLKQVAVILNPVVKAAPALIDPLYLMAQVRY

PF14559 // ENSGT00390000005979_1_Domain_2 (596, 634)

YSGEL
ENAQSILQRCLELDPASVDAHLLMCQIYLAQGNFGMCFHCLELGVSHNFQVR--------
-------DHPLYHLIKARALNKAGDYPEAIKTLKMVIKLPALKKEEGRKF-LGPCLQTSQ
RASILLELVEALRLNGELHEATKVMQDTINEFGGTPEENRITIANVDLVLSKGNVDVALN
MLRNISPKQSCYMEAREKMANVYLQTLRDRRLYIRCY------RELCEH----LPGPHTS
L

PF13432 // ENSGT00390000005979_1_Domain_5 (842, 900)

LLGDALMSILEPEKALEVYDEAYRQNPHDASLASRIGQAYVKAHQYTEAIEYYEAAQK

ENSGT00390000005979_1_Linker_5_6 (900, 907)

I
NGQDFL

PF13181 // ENSGT00390000005979_1_Domain_6 (907, 933)

CCDLAELLLKLKKINKAEKVLKQ-AL

ENSGT00390000005979_1_Linker_6_7 (933, 1022)

EHD--I-VQDIPSMMNDVKCLLLLA---
KVYESHKK---EAVIETLNKALDLQSRILKRVPLEQPEMIPSQKQLAASICIQF---AEH
Y

PF14559 // ENSGT00390000005979_1_Domain_7 (1022, 1089)

LAEKEYDKAVRSYKDVFSYLPT-DNKVMLELAQLYLLQGHLDLCEQHCAILLQTEQNHE
TASVLMADLMFRKQKHEAAINLYHQVLEKVPDNFLVLNKLIDLLRRSGKLE-DIPAFFEL
AKKVSSRVPLEPGFNYCRGIYCWHIGQPNEALKFLNKARKDSTWGQSAIYHMVQICLNPD
NEVVGGEAFENQGAES-NY-TEKKELEQQGVSTAEKLLREFYPNS-ASSQTQLRLLQGLC
RLATKEKANMEAALGSFIQIAQAEKDSVPALLALAQAYVFLKQIPKARMQLKRLAKAPWV
LSEAEDLEKSWLLLADIYCQGSKFDLALELLRRCVQYNKSCYKAYEYMGFIMEKEQSYKD
AVTNYKLAWKYSHHA----NPAIGFRLAFNYL----KDKKFVEAIEICHDV---------
-----------------------LREHPNYPKIKEEILEKARRSLRP

------------------------------------------------------------
MGSNDACLMARIIYYSQEKYFHHVQQAVAVGLEKFSNDPVLQFFKAYGVLREERIQDAIS
DLESIQ-NHQDVSLCSTIALIYAHKCCE--TIDREAIQELECSLKESRKTASDTALYYAS
LCLWLVGRHDKAREYVDRILKVSCGSR----EALVLRGWIDLTSDKPHIVKKAIKYLEQG
IQDTKDVLGLMGKATYFMMQQNYSEALEVVNQVTVASGSFLPALVLKMRLFLALQDWEQT
VETGHRILEKDESNIDAYQILAVHELTREGNMATVSFFKT-------QNHVRNLIKALET
REPQNPSLHLKKILVI-SRLCGRHQAILQQVCNFIEHIFVA-TPSYACAATELGYLHILQ
NQVKEASLWYSEGMKLNQNRMATMTGMIWCQILEGQLEEAENQLEFLKEVQ---------
QSLGKSEVLIFLQALLASKKHKGEQATTALLKETVELHFSSMQGLPLGSEYFEKLDPHFL
VYIAKEYLLFCPKQPRSPGQIVSPLLKQVMVILNPVVKAAPALVDPLYVMAQVKYLSE-P
ENAQSTLQRCLELDPTSADAHLLMAQIYLAQDNFSMCSHSLELGVSHNFQVR--------
-------DQPLYHFIKARALNKAGDYPEAIKTLKMIMKLPTLKMEEGKKF-HRPSVQPSE
RVSILLELVDALRLNGELHEATKVMQDAINEFSGTPEEVRITIANVDLALSKGNVDMALS
VLRNITPKQPCYVEAKEKMASIYLQTHKDICLYIGCY------RELCEH----LPGPHTS
LLLGDAFMNIQEPEKALEVYDEAYRKNPHDAFLVS

PF13181 // ENSGT00390000005979_1_Domain_5 (876, 903)

RIGQAYVKTHQYSKAINYYEAAQKI
SG

ENSGT00390000005979_1_Linker_5_6 (903, 907)

QDFL

PF13181 // ENSGT00390000005979_1_Domain_6 (907, 933)

CCNLAELLLKLKKFNKAERVLKQ-AL

ENSGT00390000005979_1_Linker_6_7 (933, 1022)

ECE--F-AKDIPSMMNDVKCLLLLA---
KVYESQKK---EDVIETLNKALDLQSRILKRVPLEQPEMIPSQKQLAACICTRF---GEH
Y

PF14559 // ENSGT00390000005979_1_Domain_7 (1022, 1087)

LAEKEYAKAVKAYKDALSYSPI-DNKVVLELAQLYLLQGHLDLCEQHCAILLQTEKNHE
TASVMMADLLFRKQNYEAAINLYRQVLEKAPDNFLVLRKLIDLLRRSGKLE-DTPAFFEL
AKKVSSRVPLEPGFNYCRGIYCWHIGQPNEALKFLNKARKDSTWGQSTTYYMVQICLNPD
NEIVGGEVFETLVAES------KKETEQHGVRTAEKLLREFYPHS-AFGQTQLRLLQGLC
LLATRENANVEAALGNFIEMAQAEKDSVPALLALAQAYMLLKQIPKARTQLKRLAKAPWV
LAEAEDLEKGWLLLADIYCQGGKFDLASELLRRCVQYNKSCYKAYEYMGFIMEKEQSYKD
AATNYELAWKYSHQA----NPAIGFKLAFNYL----KDKKFVEAIEVCHS----------
----------------------VLSEHPNYPKIREEILEKAQGSLRP

------------------------------------------------------------
MSSNDSALMAGIIYYCQEKYFRHVQNAATEGLEKFSNDSVLQFFKAYGLLREEHIQDAIG
ELETLK-SHPDVSLCSMMALIYAHKRCE--TIDREAISELENCLKETRKSAG

PF00515 // ENSGT00390000005979_1_Domain_0 (173, 206)

VNALYYAG
MFLWLMGSHEKAKEYVDRMLKVSSG

ENSGT00390000005979_1_Linker_0_1 (206, 407)

SR----EGYVLRGWVDFTSDKQHTVKKSIKYFDQG
IRDTKDVLGLMGKANYFMMQQNYSGALEVVNQITVTFFNFIPAFILKMRLFLAQQDWEQT
VETGHRILEKDENNIDARQVLAVHEFAREGDTDEVXXXXX----XXAINHVRNLIKALET
KEPQNPSLHLKKVIVI-SRLCGKHQMILQQIYSFIERTFMA-APSD

PF00515 // ENSGT00390000005979_1_Domain_1 (407, 440)

AQFANELGYQLILQ
DKVKEASLWYTEAMKLDESSIAALTGIIWCQILEGNLEEAEQQLEFLKEVQ---------
LSLGKSEVLTFLQALLASKKHKSEQGATALLKEAAELHFSNMQGLPLSVEYFEKLNPIFL
VNIVKEYLFFCPKQPRSPGQIISPLLKQAAVILNPVVKVAPALIDPLYLMAQVKYLSXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--------
-------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXX
XXXXXXXXXXXXXXXXXXHEATKIMQDAINEFSGTPEEIRITIANVDLALSKGNVEMALG
MLRNITPKQPYYTEA-EKMAHIYLHTRKDIRLYISCY------RELCEH----LPGPHTS
LLLGDAFMNIQEPEKALEVYDEAYRKNPHD

PF07719 // ENSGT00390000005979_1_Domain_5 (871, 904)

ASLVSRIGQAYVKTHQYNKAINYYEAAQKI
SGQ

ENSGT00390000005979_1_Linker_5_6 (904, 907)

DFL

PF00515 // ENSGT00390000005979_1_Domain_6 (907, 935)

CCDLAELLLKLKKFNKAEKVLKQ-ALDHD--F-VNDIPSMMNDVKCLLLLA---
KVYKSHKK---EEVMQTLNKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----XX
XXXXXXXXXXXXXXXXXXXXXXXXXXXVMLELAQLYLIQGDLDACEHHCTILLQSDQSH

PF07719 // ENSGT00390000005979_1_Domain_8 (1080, 1113)

E
TACVMMADLMFRKQKYETAINLYHQVLEKAPDNFSVLNKLIDLLRRSGKLE-DAPAFFEM
SKKVSSRIPLEPGFNYCKGIYCWHVGQPNEALKYLNKARKDSDWGQRATYNMVQICLNPD
NEIMGGEALETLTMEN-SS-TEKKESEQHGVRTAEKLLREFYPHN-KEGQDQLKMLQSYC
LLATKEKANVETALGAFIEIAQMEKESVPALLAMAQAYMILKQIPKARTHLKRLAKAPWA
LAEAEDL

PF07719 // ENSGT00390000005979_1_Domain_9 (1328, 1361)

EKSWILLADIYCQSGKFDMASELLRRCVQYNKS

ENSGT00390000005979_1_Linker_9_10 (1361, 1401)

CCKAYEYMGLIMEKEQSYKD
AASNYELAWKYSNRA----N

PF00515 // ENSGT00390000005979_1_Domain_10 (1401, 1470)

PSIGFKLAFNYL----KDKRFVEAIEVCHS----------
----------------------VLKEHPNYPKIREDILEKAQGSLRP

------------------------------------------------------------
MSSSDSSLMAGIIYYSQEKYFRHVQQAAAVGLEKFSNDPVLQFFKAYGVLKEEHIQDAIS
DLESIR-HHPDVSLCSTMALMYAHKRCE--TIDREAIQELECSLKDIRKAASGTALYYAG
LFLWLMGRHDKAKEYINHMLKVSRGFR----EGYVLRGWVDLTSDKPHTAKKAIEYLEQG
IQDTKDVLGLMGKARYFMMQQNYSEALEVVNQITVTSGSFLPALILKMQLFLARQDWEQT
VEMGHRILEKDESNIDACQILAVHELAREGNMTTVSYLKTQK----ATNHVQNLIKALET
REPQNPSLHLKKILVV-SRLCGSHQVILGLVCSFIERTFTV-APSYAHVATELGYLFILK
NQVKEALLWYSEAMKLDKDSMAALTGIIWCHILEGHLEEAEHQLEFLKEVQ---------
QSLGKSKVLVFLQALLTSKKHKGEQEATALLEEAVELHFSGMRGLPLGSEYLEKLDPHFL
VCIAKEYLLFCPKQPRFPGQIVSPLLQQVAVILNPVVKAAPALIDPLYLMAQVRYYS-EL
ENAQSTLQRCLELDPASVDAHLLMCQIYLAQGNFGMCFHCLELGVSHNFQVR--------
-------DHPLYHLIKARALNKAGDYPEAVKTLKMVIKLPALKKEESRKL-LRPSVQPSQ
RASILLELVEALRLNGELHEATKVMQDTINEFSGTPEENRITIANVDLVLSKGNVDVALN
MLRNITSKQSCYMEAREKMASIYLQTLRDRHLYIGCY------RELCEH----LPGPHTS
L

PF13432 // ENSGT00390000005979_1_Domain_5 (842, 900)

LLGDAFMSILEPEKALEVYDEAYRQNPQDASLASRIGQAYVKAHQYTEATEYYEAAQK

ENSGT00390000005979_1_Linker_5_6 (900, 907)

I
NGQDFL

PF13181 // ENSGT00390000005979_1_Domain_6 (907, 933)

CCDLAELLLKLKKINKAEEVLKQ-ALEHD--V-VQDIPSMMNDVKCLLLLA---
KVYKSHKK---EAVTEALKKALDLQSRILKRVPLEQPEMIPSQKQLAASICIQF---AEH
YLAEKEYEKAERSYKDALSYLPT-DNKVMLELAQLHLLQGHLDLCEQHCAILMQTDQNHE
TA

PF13174 // ENSGT00390000005979_1_Domain_8 (1083, 1113)

SVLMADLMFRKQEHDAAINLYHQVLEKAPDNFLVLNKLIDLLRRSGKLE-DIPAFFEL
AKKVSSRLPLEPGFNYCRGIYCWHTGQPNEALKFLNKARKDSTWSQSAIYHMVQICLNPD
NEVVGGEAFENQEAEI-NY-TEKKELEQQGVSTAEKLLCEFHPHS-ASSQTQLQLLQGLC
QLATREKANIEAALGRFLQIAQAEKESIPALLALAQAYVFLKQIPKARMQLKRLAKAPWM
LSEADDLE

PF13181 // ENSGT00390000005979_1_Domain_9 (1329, 1360)

KSWLLLADIYCQGGKFDLASELLRRCVQYNKSCYKAYEYMGFIMEKEQSYKD
AVTNYKLAWKYSHHA----SPAVGFRLAFNYL----KDKKFVEAIEICHEV---------
-----------------------LREHPNYPKIREEILEKARRSLRP

------------------------------------------------------------
--SSDCALTAGIIYYSQEKYFRHVQQAAAQGLEKFSNDPVLQFFKAYGVLREEHIQDAII
TLESIR-NHPDVALCSTMALIYAHKHCE--VVDREAVQELESRLKEIRKKASGTALYYVS
LFLWLMGCHDKAKEYIDRMLKVSNNSR----EGYVLRGWVDLTSGEPHAVKKSIKYLDQG
IQDSKDVLGLMGKATYFLVHQNYTGGLELVNQVTVVSGSFLPALVLKMRLFLAQQDWEQA
VETAHRILEKDENNIDARQILALHVLAREGNMTTVSSLAPKA-----ADRVRSLIKALET
REPQNPSLHLKKSLAV-SRLCGRQQVILQQMCSFLERTFMA-APCYTHVATELGYLFILQ
Q-MKEASLXXXXXXXXXXXXXXXXXXIIWCQILEGQLEEAEHQLEFLKEVQ---------
QSLGKSKVLLFLQALLTSRKYKGDQEVTSLLKEVAELHFSSMQGLPLGAEYFEKLDPLFL
ICIAKEYLHFCPKQPRSPGQIVSPFLKQVTMILSPVLKAAPALMEPLYVMAQVKYLS-EL
ENAQNTLQRCLELDPTSADAHLLMAQVYLAQGNFAM-THCLELGVSHNXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--X--X---X---XXXXXXX-XXXXXXXXX
XXXXX---XXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXX--XXXXXXXX---
-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXELCEH----LPG

PF00515 // ENSGT00390000005979_1_Domain_4 (837, 870)

PHTS
LLLGDAFMNILEPEKALEVYDAAYRKNPHDAFLVSRIGRACVKAHEYTKAINYYEAAQKM
SGLDFLCCDLAELLLRLKKFNKAERILEQ-ALEHD---SVNDIPSMMTDIKCLLLLA---
KVYNSQKK---EDVIKTLNKAMELQTRILKRVPLEQPEMMPSQKQLA

PF00515 // ENSGT00390000005979_1_Domain_7 (1008, 1045)

ASICTQV---GQH
YMAEKEYAKAERSFKDALTYCPT-DNKVELELAQLFLLQGHLDLCEQHCAILLQTQKSHE
AATAMMADLLFRKQKQEAAVTLYHQVLQEVPXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXX
XXXXXXXXXXXXXXXX-XX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXTTREKANMEMALNSFIEMAQAERDSVSVLLAMAQAYMLLKQVPKARTQLKRLAKAQWT
LAEADDLEKSWLLLADIYCQGGKFDLSTELLRRCXXXXXXXXXXXXXXXXXXXXXXXXXX
----XXXXXXXXXXXXXXXXXXXXFKLAFNYL----KDKRFMEAIEVCHY----------
----------------------VLREHPNYPKIREEILQKAQGSLRP