Query Results 

------------------------------------------------------------
-----MEALAQRALISYYCQEGYFR-HLQLAANEGLKKF-GNDPVFLFYRAYGMMLEGHV
QEAIRELDSIKNKQEVSLCTMMALIYAHKKSSNP---DRDAILELDTKMKEHRKTAGQQA
LYYAGLFLWHLGRQDKAREYVDRMIKVSN-SNKEGLILKAWLDLTCGKEAYIKKAVKYFD
EGMQGGNDPFALLGKAQYFEMRQNYSGALETVNHIIANFPDFLPAFIKKMKLHLALQDWE
QAVETAQRLLKKDTLNLEAIRMEALNFLCREGNIPEA--------AAKLGDLINALEKLE
PHNPQLFCKMALAFSRTCGRNQLILQQTQILVERAFDLASHDSEIATELGYQMILQERVK
DALKWYKTAMVLDETSVSALTGIIRCQITEGQLEDADQQLEFLNEIQQSIGKSGELSFLR
ALLAMKKHQKQEEVIHLLNDVLETHFSSLHGLPLGVQYFEKLNPDFLLEIVREYLNFCPT
QPANSGQPPSPLLKHCASVLETVVKTVPGLQHAVFLIGKVKYLS---GDI-EASRSILQH
CLDQNPSYPDAHLLMAQVHLSQNNFKLCSQSLELCLSYNFEVREHPLYHLIKAQTQKKMG
EISEAIKTLQMAMSLPGMRRSGAFSKAKAKRNEIDASIRVSV-FLELVDAHHLNGEQHEA
AKVLQDAINEFAGTPEELR

PF07721 // ENSGT00390000005979_0_Domain_8 (740, 762)

VVIANADLALAQGDIEQALTML

ENSGT00390000005979_0_Linker_8_9 (762, 814)

RNITSEQPYFVQAKIKMAD
IYLQYRKEKKLYATCYRDL---VDKLPSCHTFL

PF07719 // ENSGT00390000005979_0_Domain_9 (814, 842)

LLGDAYMNIQEPEEAIEIYEQALKKNP
RDITLASKIGKALIKTHNYSKAINYYEAALKNGQQNILCYDLAELLLKLRQYEKAEKVLQ
QALDHEP----------------ENELSSLMEDGRYQVLLAKIYSKMEKTDEAIVSLQQA
RELQARILKRVQIEQLDAVPAQKQLVAEICAEIAKHCTAQRNYEKAIKFYKEALVHCETD
NKVMLELARLYLAQDDTDACQHQCALLLKNDQDNEAATMMMADLMFKKQDYEQAVFHFQQ
LLERKPDNYASLSRLIDLL-RRAGKLEEVPRFLVMAETHSSRAKLEPSFHYCKGLYLWYT
GEPNDALRHFNRARKDSDWGQNAVYNMIEICLNPDNETVGGEVFENLDGDTGNSTEKQES
VQLAVRTAEKLLKELKPQTIQGHIQLRIMENHCLMATKQKSNVEQALNTFTEVVVAEKDH
IPALLGMATAYMILKQTPRARNQLKRISKMNWNPIDAEDFEKSWLLLADIYIQSAKYDMA
GELLKQCLRRNRSCCKAYEYMGYIMEKEQAYKDAAVNYEMAWKYGNQTNPTIGYKLAFN-
-YLKAKRY---------VEAIDICHK-VLKAHPNYPKIRKEILDKARASLRT

------------------------------------------------------------
-----MDSQGLKTLINYYCQERYYH-HVLLVASEGMKKY-SSDPVFRFYHAYGTLMEGKA
QEALREFEAIKNKQDVSLCSLMALMYVHKMSPNP---DREAILELDTKMKEQRKEAGRKA
LYHAGLFLWHIGRHDKAREYIDRMSKMPH-DSNEGPILKAWLDITRGKEPYAKKALRYFE
EGLQDGNDIFALLGKVLCLEIRQNYSGALETVSQIIVNFPSFLPAFEKKMKLQLALQDWD
QTVETAQRLLLQDNHNVEALRMLALYYLCREGDVEKA--------ATKLENLGNALDVME
PQNAQLFYKITLAFSRTCGRNQLILQRVQSFLEKAFSLTPQQAEIATELGYQMILQGKVK
EAWKWYRTAMTLNESNISAVTGLIRCQLIEGQLQDADQQLEFFSEFQQSMGKSAELMYLH
AVLATKKNNRQDEVINLLNDVVNTHFSHLEDLPLGIQYFEKLNPDFLLEVVTEYLNLCPI
QPAGPGQPLSPVLRRCSSVLETIIRSVPGLPQAVFLMAKVKYLS---GDT-EAAYNNLQH
CLEHSPSYAEAHLLMAQVYLSQDKVKLCSQSLELCLSYNFNVREYPLYHLIKAQSQKKMG
EVAEAIKTLHMAMNLPGMRRSRASSKSK-HRTEVDASHRLSI-FLELVEVHRLNGEQHEA
AKVLQDAIHEFSGTCEELRVTIANADLALAQGDTDRALSMLRNVTTEQPYFIEAKEKMAD
IYLKHRKEKMLYITCYREI---AERMPSP

PF13181 // ENSGT00390000005979_0_Domain_9 (810, 842)

RSFLLLGDAYMNIQEPEEAIVAYEQALNQNP
KDGTLARKIGKALVKTHNYSKAITYYEAALKSGQQNCLCYDLAELLLRLKLYEKAEKVLQ
HSLAHEP----------------VSELSALMVDGRSQVLLAKVYSKMERPSDAIAALQQA
RELQARILKRVQMEQPDAVPSQKHFAAEICAEIAKHSAAQRDYEKAITFYREALVHCETD
SKIMLELAQLYLAQEDLDASLRHCALLLQRDQDNEPATMLMADLMFRKQDYEQAVYHLQQ
LLDRKPDNFMTLSRLIDLL-RRCGKLEDVPRFFLMAEKHNSRTKLEPGFQYCKGLHFWYT
GEPNDALRHFNKARKDSDWGQNALYNMIEICLNPDNETIGGEVFENLNGDLGTSPEKQES
VQLAVRTAEKLLKELKPQTVQGRLQLRIMENCCLMATKQKSSVEQALNTFTEIAASEKDH
IPALLGMATAYMILKQTPKARNQLKRIAKMPWNPIEAEDLE

PF13181 // ENSGT00390000005979_0_Domain_15 (1302, 1328)

KSWLLLADIYIQSAKYDMA
EELLKRCLCHNRSCCKAYEYMGYIMEKEQAYTDAAFNYEMAWKHSNQTNPAVGYKLAFN-
-YLKAKRY---------VDAIDVCHQ-VLEAHPTYPKIRKDILDKARASLRP

------------------------------------------------------------
-----MDSQGLKTLINYYCQERYYH-HVLLVASEGMKKY-SSDPVFRFYHAYGTLMEGKA
QEALREFEAIKNKQDVSLCSLMALMYVHKMSPNP---DREAILELDTKMKEQRKEAGRKA
LYHAGLFLWHIGRHDKAREYIERMSKMPH-DSNEGPILKAWLDITRGKEPYAKKALRYFE
EGLQDGNDIFALLGKVLCLEIRQNYSGALEIVSQIIVNFPSFLPAFEKKMKLQLALQDWD
QMVETAQRLLLQDNHNVEALRMLALYYLCREGDIEKA--------ATKLENLGNALDVME
PQNAQLFYKITLAFSRTCGRNQLILQKVQSFLEKAFSLTPQQAEIATELGYQMILQGKVK
EAWKWYRTAMTLNESNISAVTGLIRCQLIEGQLQDADQQLEFFSEFQQSMGKSAELMYLH
AVLATKKNNCQDEVINLLNDVVNTHFSHLDDLPLGVQYFEKLNPDFLLEVVTEYLNLCPI
QPAGPGQPLSPVLRRCSSVLETIIRSVPGLPQAVFLMAKVKYLS---GDT-EAAYNNLQH
CLEHSPSYAEAHLLMAQVYLSQDKVKLCSQSLELCLSYNFNVRDYPLYHLIKAQSQKKMG
EVAEAIKTLHMAMNLPGMRRSRASSKSK-HRTEVDASHRLSI-FLELVEVHRLNGEQHEA
AKVLQDAIHEFSGTCEELRVTIANADLALAQGDTDRALSMLRNVTTEQPYFIEAKEKMAD
IYLKHRKEKMLYITCYREI---AERMPSPRSFLLLGDAYMNIQEPEEAIVAYEQALNQNP
KDGTLARKIGKALVKT

PF14559 // ENSGT00390000005979_0_Domain_9 (857, 931)

HNYSKAITYYEAALKSGQQNCLCYDLAELLLRLKLYEKAEKVLQ
HSLAHDP----------------VSELSALMVDGRSQVLLAKVYSKMERPSDAIAALQQA
RELQARILKRVQMEQPDAVSSQKHFAAEICAEIAKHSAAQRDYEKAITFYREALVHCEAD
SKIMLELAQLYLAQEDLDSSLRHCALLLQRDQDNEPATM

PF13174 // ENSGT00390000005979_0_Domain_13 (1060, 1087)

LMADLMFRKQDYEQAVYHLQQ
LLERKPDNFMTLSRLIDLL-RRCGKLEDVPRFFLMAEKHNTRTKLEPGFQYCKGLHFWYT
GEPNDALRHFNKARKDSDWGQNALYNMIEICLNPDNETIGGEVFENLNGDLGSSPEKQES
VQLAVRTAEKLLKELKPQTVQGRLQLRIMENCCLMATKQKSSVEQALNTFTEIAASEKDH
IPALLGMATAYMILKQTPKARNQLKRIAKMPWNPIEAEDLE

PF13181 // ENSGT00390000005979_0_Domain_15 (1302, 1328)

KSWLLLADIYIQSAKYDMA
EELLKRCLCHNRSCCKAYEYMGYIMEKEQAYTDAAFNYEMAWKHSNQTNPAVGYKLAFN-
-YLKAKRY---------VDAIDVCHQ-VLEAHPTYPKIRKDILDKARASLRP

------------------------------------------------------------
-----MDSQGLKTLIHYYCQERYFH-HVLLIASEGVKRY-ANDPVFRFYHAYGTLMEGKT
QDALREFEAIKNKQDVSLCSLIALIYAHKMSPNP---DREAILESDARMKEQRKGAGPKA
LYHAGLFLWHIGRLDKAREYIDRMIKMSN-GSKEGQILKAWLDLTKGKEPYTKKALKCFE
EELQDGNDIF

PF13174 // ENSGT00390000005979_0_Domain_1 (251, 280)

ALLGKAQCLEMHQNYSGALEAVNQIIVNFPSFLPAFIKKMKLQLALQDWD
QTVETAQRLMLQDNQNVEALRILALYYLCREGDIEKA--------ATKLENLESALDAME
PQNGQLFYKITLAFSRTCGRSQLILQKIQTLLERAFSLTPQQSEFAT

PF07719 // ENSGT00390000005979_0_Domain_3 (408, 436)

ELGYQMILQGKVK
EALKWYKTALTLDETNIPALAGFIRCQLIEGQLQDADQQLEFLSEIQQSIGKSPELTYLR
AILAMKKNKPREEVINLLNDVLDTHFSQLEDLPLGIQYFESLNPDFLLEIITEYLNFCPM
QPASPGQPLSPLLQRCTSVLETIVRTVPGLQQAVFLIAKAKYLS---GDI-EAAYNNLQH
CLEHSPSYADAHLLIAQVYLSQEKFKLCSQSLELCLSYNFKVREYPLYHLIKAQSQKKMG
EIAEAIKTLHMAMSLPGMRRIGSSSKSKYRKTEVDANHRLSI-FLELVEVHRLNGEQHEA
AKVLQDAIHEFSGTSEELRVTIANADLALTQGDVERALSMLRNVTAEQPYFIEAKEKMAD
IYLKHRKEKMLYISCYREI---AERMPSPRS

PF13414 // ENSGT00390000005979_0_Domain_9 (812, 871)

FLLLGDAYMNIQEPEEAIVAYEQALNQNP
KDGTLASKIGKALVKTHNYAKAITYYEAALKSGQQNYLCCDLAELLLKLKWYDKAEKVLQ
HALAREP----------------VNELSALMEDGRS

PF00515 // ENSGT00390000005979_0_Domain_10 (937, 963)

HVLLAKVYSKMERPDDAITSLQRA
RE

ENSGT00390000005979_0_Linker_10_12 (963, 998)

LQTRVLKRVQMEQPDAAPAQKQLAAEICAGIAKHS

PF14559 // ENSGT00390000005979_0_Domain_12 (998, 1063)

VAQRDYEKAIKFYREALVHCDTD
NKIMLELARLYLAQEDPDACLRQCALLLQSDQDNEAATMMMADLMFRKQDYEQAVFHLQQ
LLERKPDNYMTLSRLIDFL-RRCGKLEDVPRFFSMAEKRNSRAKLEPGFQYCKGLYLWYT
GEPNDALRHFNKARKDSDWGQNALYNMIEICLNPDNETVGGEVFENLDGDLGNSTEKQES
VQLAVRTAEKLLKELKPQTIQGHVQLRIMENYCLVATKQKSNVEQALNTFTEIASSEKDH
VPAILGIATAYVILKQTPRARNQLKRIAKMNWNPIDAEDFEK

PF13181 // ENSGT00390000005979_0_Domain_15 (1303, 1330)

GWLLLADIYIQSAKYDMA
EELLKRCLRHNKSCCKAYEYMGYIMEKEQAYTDAALNYEMAWKHSNQTNPAVGYKLAFN-
-YLKAKRY---------VDAIDICHQ-VLEAHPTYPKIRKDILDKARTSLRP

------------------------------------------------------------
-----MDSQELKTLINYYCQERYFH-HVLLVASEGIKRY-GSDPVFRFYHAYGALMEGKT
QEALREFEAIKNKQDVSLCSLLALIYAHKMSPNP---DREAILESDARVKEQRKGAGEKA
LYHAGLFLWHIGRHDKAREYIDRMIKISD-GSKQGHVLKAWLDITRGKEPYTKKALKYFE
EGLQDGNDTFALLGKAQCLEMRQNYSGALETVNQIIVNFPSFLPAFLKKMKLQLALQDWD
QTVETAQRLLLQDSQNVEALRMQALYYVCREGDIEKA--------STKLENLGNALDAME
PQNAQLFYNITLAFSRTCGRSQLILQKIQTLLERAFSLNPQQSEFATELGYQMILQGRVK
EALKWYKTAMTLDETSVSALVGFIQCQLIEGQLQDADQQLEFLNEIQQSIGKSAELIYLH
AVLAMKKNKRQEEVINLLNDVLDTHFSQLEGLPLGIQYFEKLNPDFLLEIVMEYLSFCPM
QPASPGQPLCPLLRRCISVLETVVRTVPGLLQTVFLIAKVKYLS---GDI-EAAFNNLQH
CLEHNPSYADAHLLLAQVYLSQEKVKLCSQSLELCLSYDFKVRDYPLYHLIKAQSQKKMG
EIADAIKTLHMAMSLPGMKRIGASTKSKDRKTEVDTSHRLSI-FLELIDVHRLNGEQHEA
TKVLQDAIHEFSGTSEEVRVTIANADLALAQGDIERALSILQNVTAEQPYFIEAREKMAD
IYLKHRKDKMLYITCFREI---AERMANP

PF13181 // ENSGT00390000005979_0_Domain_9 (810, 842)

RSFLLLGDAYMNILEPEEAIVAYEQALNQNP
KDGTLASKMGKALIKTHNYSMAITYYEAALKTGQKNYLCYDLAELLLKLKWYDKAEKVLQ
HALAHEP----------------VNELSALMEDGRCQVLLAKVYSKMERLGDAITALQQA
RELQARVLKRVQMEQPDAVPAQKHLAAEICAEIAKHS

PF14559 // ENSGT00390000005979_0_Domain_12 (998, 1064)

VAQRDYEKAIKFYREALVHCETD
NKIMLELARLYLAQDDPDSCLRQCALLLQSDQDNEAATMMMADLMFRKQDYEQAVFHLQQ
LLERKPDNYMTLSRLIDLL-RRCGKLEDVPRFFSMAEKCNSRAKLEPGFQYCKGLYLWYT
GEPNDALRHFNKARKDRDWGQNALYNMIEICLNPDNETVGGEVFENLDGDLGNSTEKQES
VQLAVRTAEKLLKELKPQTVQGHVQLRIMENYCLMATKQKSNVEQALNTFTEIAASEKEH
IPALLGMATAYMILKQTPRARNQLKRIAKMNWNAIDAEEFE

PF13181 // ENSGT00390000005979_0_Domain_15 (1302, 1329)

KSWLLLADIYIQSAKYDMA
EELLKRCLRHNRSCCKAYEYMGYIMEKEQAYTDAALNYEMAWKYSNRTNPAVGYKLAFN-
-YLKAKRY---------VDSIDICHQ-VLEAHPTYPKIRKDILDKARASLRP

------------------------------------------------------------
-----MDSQELKTLINYYCQERYFH-HVLLVASEGIKRY-GSDPVFRFYHAYGTLMEGKT
QEALREFEAIKNKQDVSLCSLLALIYAHKMSPNP---DREAILESDARVKEQRKGAGEKA
LYHAGLFLWHIGRHDKAREYIDRMIKISD-GSKQGHVLKAWLDITRGKEPYTKKALKYFE
EGVQDGNDTFALLGKAQCLEMRQNYSGALETVNQIIVNFPSFLPAFVKKMKLQLALQDWD
QTVETAQRLLLQDSQNVEALRMQALYYVCREGDIEKA--------STKMENLGNALDAME
PQNAQLFYNITLAFSRTCGRSQLILQKIQTLLERAFSLNPQQSEFATELGYQMILQGRVK
EALKWYKTAMTLDETSVSALVGFIQCQLIEGQLQDADQQLEFLNEIQQSIGKSAELIYLH
AVLAMKKNKRQEEVINLLNDVLDTHFSQLEGLPLGIQYFEKLNPDFLLEIVMEYLSFCPM
QPASPGQPLCPLLRRCISVLETVVRTVPGLLQTVFLIAKVKYLS---GDI-EAAFNNLQH
CLEHNPSYADAHLLLAQVYLSQEKVKLCSQSLELCLSYDFKVRDYPLYHLIKAQSQKKMG
EIADAIKTLHMAMSLPGMKRIGASTKSKDRKTEVDRSHRLSI-FLELIDVHRLNGEQHEA
TKVLQDAIHEFSGTSEEVRVTIANADLALAQGDTERALSILQNVTAEQPYFIEAREKMAD
IYLKHRKDKMLYITCFREI---AERMANPRSFLLLGDAYMNILEPEEAIVAYEQALNQNP
KDGTLASKMGKALIKTHNYSMAITYYEAALKTGQKNY

PF13181 // ENSGT00390000005979_0_Domain_9 (878, 903)

LCYDLAELLLKLKWYDKAEKVLQ
HALAHEP----------------VNELSALMEDGRCQVLLAKVYSKMERLGDAITALQQA
RELQARVLKRVQMEQPDAVPAQKHLAAEICAEIAKHS

PF14559 // ENSGT00390000005979_0_Domain_12 (998, 1064)

VAQRDYEKAIKFYREALVHCETD
NKIMLELARLYLAQDDPDSCLRQCALLLQSDQDNEAATMMMADLMFRKQDYEQAVFHLQQ
LLERKPDNYMTLSRLIDLL-RRCGKLEDVPRFFSMAEKRNSRAKLEPGFQYCKGLYLWYT
GEPNDALRHFNKARKDRDWGQNALYNMIEICLNPDNETVGGEVFENLDGDLGNSTEKQES
VQLAVRTAEKLLKELKPQTVQGHVQLRIMENYCLMATKQKSNVELALNTFTEIAASEKEH
IPALLGMATAYMILKQTPRARNQLKRIAKMNWNAIDAEEFE

PF13181 // ENSGT00390000005979_0_Domain_15 (1302, 1329)

KSWLLLADIYIQSAKYDMA
EELLKRCLRHNRSCCKAYEYMGYIMEKEQAYTDAALNYEMAWKYSNRTNPAVGYKLAFN-
-YLKAKRY---------VDSIDICHQ-VLEAHPTYPKIRKDILDKARASLRP

------------------------------------------------------------
------------TLVNYYCQKKYFH-HASFVAREGMKKY-ANDPFFRFYHAYCILMEGKA
QEALREFEAIKNKQDVSLCSLIALMYVHKLSPNP---DREAIMELDTKMKEQRKDAGPKT
LYHAGLFLWHIGRLEKAREYIDRMLKVAN-DSNEGQILKAWLDIARGKEPYTKKALRCFE
EGLQDGNDIFALLGKVQCLEKRQDYSGALETVNHIIVNFPGFLPAFEKKM

PF13432 // ENSGT00390000005979_0_Domain_2 (291, 337)

KLHLALKDWD
QAVETAQRLLLQDNENVEALRMLALYYLCREGDIEKA--------TVTLEKLGNALDVTE
PQNAQLFHRITVAFSRTCGRSQVILQKIQTFLEKAFSLSPQLPEIATELGYQMIFQGKAK
EAWNWYKTAMALNETNISAVIGLIRCQLMEGQLQDADQQLEFFSEFQQSMGRSAELMYLQ
AVLAMKKNRQQEEIINLLNDIVDTHFSHLEDLPLGIEYFEKLNPDFLLEVITEYLNICPI
QPTDPGQPLSPVLKCCTSVLETIIRTVPGLQKAVFLMAKVKYLS---GDI-DAAHSTLQR
CLERSPSCADAHLLMAQVYLFQEKVKLCSQSLELCLSYNFNVREYPLYHLIKAQSQKKMG
EIAEAIKTLHMAMNLPGMRRIQASSKSKLTKTEVDTSHRLSI-FLELVEVHCLNGEQHEA
AKVLQDAIHEFSGTCEELRVTIANADLALAQGDTERALSVLRNVTTAQPYFIEAKEKMAD
IYLKHRKEKMLYITLVAYMTYLLPKMPSQISFSFLFT----CFLPEEAIVAYEQALNQNP
KDGTLANKMGRALVKTH

PF14559 // ENSGT00390000005979_0_Domain_9 (858, 924)

NYSKAITYYEAALKNKQHSYLYFDLAELLLKLKQYDKAEKVLQ
HALAHEP----------------VNELSVLMEDARSQVLLAKVYSKMQRPNDAITSLQQA
RELQARVLKRVEMEQPDAVPAQKHLAAKICAEMAKHAVVQQDYERAIRFYKEALIHCETD
SKIMLELAQLYLAQDDLDASLRHCVLLLQSDQDNELATMMMADLMFRKQDYEQAVFHLQQ
LLERKPDNYMTLSRLIDLL-RRSGKLDDVPRFFSMAEKYNSRIKLEPGFQYCKGLHLWYT
GEPNDALRHFNKARKDSDWGQNALYNMIEICLNPDNETIGGEVFENLNGDLGNSTEKQES
VQLAVRTAEKLLKELKPQTTQGHVQLRILENYCLMATKQKSNVEQALSAFTEIAASEKDH
IPALLGMATAYMILKQTPRARNQLKRIAKMTWNPVDAEEFE

PF13181 // ENSGT00390000005979_0_Domain_15 (1302, 1329)

KSWLLLADVYIQLAKYDMA
EELLKRCLRHNRSCCKAYEYMGYMMEKEQAYADAALNYEMAWKHGNQSNPAMGYKLAFN-
-YLKAKRY---------VDAIGICHQ-VLKTHPTYPKIKKDILDKARTCLRP

------------------------------------------------------------
------------TLINYYCQEQYFH-HVLLVASEGMKRY-GSDPVFRFYHAYGTLMEGKI
QEALREFEAIKHKQDVSLCSLIAVIYAHKISPNP---DREAILESDARVKEQRKGADQ

PF13181 // ENSGT00390000005979_0_Domain_0 (179, 207)

KA
LYHAGLFLWHLGRHDKAREYIERMIKMPN-NSNEGQILKAWLDITRGKESYAKKALRCFE
EGLQDGKDIFALLGKAQCLEMRQNYSGALETVNQIIVNFPSFFPAFIKKMKLQLALQDWD
QMVETAQRLLLQDAQNVEALRMLALYYLCREGDIEKA--------TTELENLRNALDVME
PQNAQLFYKITIAFSRTCGRNQLILQRIQKLLEKAFSLTPQQSEFAAEIGYQMILQGKVK
EALSWYQTAMTLDNTSISALVGFIRCQLMDGQLQEADQQLEFLSEVQQSVEKSAELIYLH
AFLAMKKNKRQEEVIQLLNDVLDTHFLHLEDLPLGIQYFETLNPDFLLEIITEYLNFCPM
PPASPGQPLTPFLRRCTSVLETIVRTVPGLLQAVFLIAKVKYLS---GNT-EAAYRNLQH
CLDHSPSYADAHLLMAQVYLSQEKFKLCSQSLELCLSYNFNVREYPLYHLIKAQSQKKMG
EITEAIKTLHMAMSLPGMRRTGASSKSKYRKAEVDMGHRLSV-FLELVEVHRLNGEQHEA
AKVLQDAIHEFAGTSEEL

PF07721 // ENSGT00390000005979_0_Domain_8 (739, 762)

RVTIANADLALAQGDVEQALSILRNVTTEQPYFIEAKLKMAD
IYLKHRKEKILFITCYREI---AERMPSPRSFLLLGDAYMNIQEPEEAIVAYKQALNQNP
KDGMLASK

PF13432 // ENSGT00390000005979_0_Domain_9 (849, 903)

IGKALVKTHNYSKAITYYEAALKSGQQNYLCYDLAELLLKLKLYEKAEKVLQ
HALSHEQ----------------VNELSDLIEDGRSQVLLAKVYSKIGRPGGAVTSLQQA
RELQARVLKRVQMEQPDAVPAQKHLAAEICAEIAKHSVAQQDYEKAIMFYREALVHCETD
NKIM

PF07721 // ENSGT00390000005979_0_Domain_12 (1025, 1043)

LELARLHLAQGDPDACLRHCVMLLQRDQDNEAATTMMADIMFRKQDYEQAVFHLQQ
LLERKPDNYMTLSRLIDLL-RRCGKFDDIPRFFVMAEKCNSRAKLEPGFHYCKGLYLWYT
GEPNDALRHFNKARKDSEWGQNALYNMIEICLNPDNETVGGEVFENLDGDLGNSTEKQES
VQLAVRTAEKLLKELKPQTVQGHVQLRIMENYCLMATKQKPNVEQALNTFTEVAKSENDH
IPALLGMATAYMILKQTPKARNQLKRIAKMNWNAIDAEEFE

PF13181 // ENSGT00390000005979_0_Domain_15 (1302, 1329)

KSWLLLADIYIQSAKYDMA
EDLLRQCLRHNRSCCKAYEYMGYIMEKEQAYSDAASNYEMAWKYGNQTNPAVGYRLAFN-
-YLKAKRY---------VDAIDVCHQ-VLEIHPTYPKIRKDILDKARASLRP

------------------------------------------------MDSQ-------G
LKMSQPKSHTRQALINYYCQEGYFH-HVLLVASEGMKSY-GSDPVFRFYHAYATLMEGKI
QEALREFEAIKNKQDVSLCSLIALIYAHKMSPNP---DREAILESDARVKEQRKGAGPKV
LYHAGLFLWHIGRHDKAREYIDRMIKISN-GSKEGQVLRAWLDITRRKEPYTKKALRYFE
EGLQDGNDIFALLGKAQCLEMRQNYSGALETVNQIIMNFPGFLPAFVKKMKLQLALQDWD
QTVETAQRLMLQDNQNLEALRMLALYYLCREGDIEKA--------ATQLENLGNALDAVE
PQNAQLFYTITIAFSRICGRSQLILQKTQTLLERAFSLNPQQSEFATELGYQMILHGKVK
EALKWYKTAMTLDETSVSALIGFIQCQLIEGQLQDADQHLEFLREVQQSIGKSAELTYLH
AVLAMRKNKRQEEVINLLNDVLDTHFSQLEDLPLGIQYFEKLNPDFLIEIITEYLNFCPM
QPASPGQPLSPLLRRCTSILETIVRTVPGLLQAVFLIAKVKYLS---GDI-EAAYNNLQH
CLEHSPSYADAHLLMAQVYLSQEKFKLCSQSLELCLSYNFKVREYPLYHLIKAQSQKKMG
EIAEAIKTLHMAMSLPGMRRIGSSSKTKYRKTEVDASHRLSV-FLELAEVHRLNGEQHEA
AKVLQDAIHEFSGTSEELRVTIANADLALAQGDVERALSMLQNVTAEQPYFIEAKEKMAD
IYLKHRKEKMLYITCYREM---AERMPSP

PF13181 // ENSGT00390000005979_0_Domain_9 (810, 841)

RSFLLLGDAYMNIQEPEEAIVAYEQALNHNP
KDGTLASKIGKALVKTHNYSKAITYYEAALKSGQQNYLCYDLAELLLKLKWYDKAEKVLQ
HALAHEP----------------VNELSALMEDGRFQVLLAKVYSKVDRPDDAVTSLQQA
RELQARVLKRVQMEQPDAVPAQKHLAAEICAEIAKHSVAQRNYEKAIKFYREALVHCETD
NKIMLELARLYLLQDDPDACLRHCALLLQNDQDNEAATMMMADLMFRKQDYEQAVFHLQQ
LLERKPDNYMTLSRLIDFL-RRCGKLEDVPRFFLMAEKRNSRAKLEPGFQYCKGLYLWYT
GEPNDALRHFNKARKDSDWGQNALYNMIEICLNPDNETVGGEVFENLDADPGNSTEKQES
VQLAVRTAEKLLKELKPQTVQGQVQLRIMENYCLMATKQKSNVEQALNTFTEIAASEKDH
VPALLGMATAHMILKQTPRARNQLKRIAKMNWNPIDAEDFE

PF13181 // ENSGT00390000005979_0_Domain_15 (1302, 1329)

RSWLLLADIYIQSAKYDMA
EELIKRCLRHNRSCCKAYEYMGYIMEKEQAYMDAALNYEMAWKHGNQTNPAVGYKLAFN-
-YLKAKRY---------VDAIDVCHQ-VLEAHPTYPKIRKDILDKARTSLRP

------------------------------------------------------------
-----MDSQGLKTLINYYCQERYFH-HVLLVASEGMKKY-GSDPVFRFYHAYGTLMEGNT
QEALREFEAIKSKQDVSLCSLIALIYAHKMSPNP---DREAILESDARMKEQRKGAGQ

PF13181 // ENSGT00390000005979_0_Domain_0 (179, 208)

KA
LYHAGLFLWHLGRHDKAREYIDRMIKISD-GSSEGHVLKAWLDITRGKEPYAKKALRYFE
EGLQDGNDIFALLGKAQCLEMRQNYSGALETVNQIIVNFPSFIPAFVKKMKLQLALQDWD
QTVETAQRLLLQDNQNVEALRMLALYHLCREGDIEKA--------STKLENLGKALDAME
PQNAQLFYKMTIAFSRTCGRSQLILQKIQTLLEKSFSLSPQQSEFATELGYQMILQGKIK
EALKWYKTAMTLNETSVSALVGFIRCQLIEGQLQDADQQLEFFSEIQQSIGKSAELTYLH
AILAMKKNKRQEEVINLLNEVLDIHFSNLEDLPLGIQYFEKLNPDFLLEIITDYLNFCPM
QPASPGQPLSPLLRRCTSVLEIIVRTIPGLLQAVFLVAKVKYLS---GDF-EAAYNNLQH
CLDHSPSYADAHLLMAQVYLSQEKFKLCSQSLELCLSYNFNVRDYPLYHLIKAQSQKKMG
EIAEAIKTLHMAMSLPGMKRTGASSKPKCKNTEVDTSHRLSI-FLELVEVHHLNGEHHEA
AKVLQDAIHEFSGTSEELRVTIANADLALTQGDVERALNMLRNVTAEQPYFIEAKEKMAD
IYLKHRKEKMLYITCYREI---AERIPSPRSFLLLGDAYMNIQEPEEAIVAYEQALNQNP
KDGTLASKIGKAL

PF14559 // ENSGT00390000005979_0_Domain_9 (854, 931)

IKTHNYSKAITYYEAALKSGQQNYLCYDLAELLLKLKWYDKAEKVLQ
HALAHEP----------------VNELSALMEDGRCQVLLAKIYSQMERPDDAITALQQA
RELQARVLKRVQMEQPDAVPAQKHLAAEICAEIAKHS

PF14559 // ENSGT00390000005979_0_Domain_12 (998, 1064)

VAQRDPEKAIKFYREALVHCETD
SKIMLELARLYLAQGDPDACMRQCALLLQNDQDNEAATTMMADLMFRKQDYEQAVFHLQQ
LLERKPDNYMTFSRLIDLL-RRCGKLEDVPRFFVMAEKRNSRAKLEPGFQYCKGLYLWFT
GEPNDALRHFNKARKDSEWGQNALYNMIEICLNPDNETVGGEVFENLDGDLGNSTEKQES
VQLAVRTAEKLLKELKPHTVHGHIQLRIMENYCLLATKQKSNVEQALNTFTKIAASEKDN
LPALLGMATAHMILKQIPKARNQLKRIAKMTWNPIDADDFE

PF13181 // ENSGT00390000005979_0_Domain_15 (1302, 1328)

KSWLLLADIYIQSAKYDMA
EELLKRCLHHNKSCCKAYEYMGYIMEKEQGYTDAALNYEIAWKRGNQTNPAVGYKLAFN-
-YLKAKRY---------VDAIDICHQ-VLEAYPSYPKIRKDILDKARSSLRP

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------REAVLESDARLKEQRKGAGQKA
FYYAGLFLWHVGRHDKAREYIDRMVKMSD-GSKEGQVLKAWLDITRGKEPYTKKALRYFE
EALQDGNDIFALLGKAQCLEIRQNYSGALETVNQITVKFPSFLPAFVKKMKLQLALQDWD
QTVETAERLMLQDNKNVEALRMLALYYLCRKGDIEKA--------TSKLENLGNALEATE
PQNAQLLCKMTKAFSRTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXELTYLH
AVLAMKKNKQQEEVISLLNDALDTHFSHLEDLPLGIQYFEKLNPDFLLEIITEYLNFCPM
QPASPGQPLSPFIRRCISILETIVRTVPGLLQAVFLIAKVKYLSXXXXXXXXXXXXXXXX
XXXXXXXX----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXVREYPLYHLVKAQSQKKMG
EIAEAIKTLHMAMSLPGMRKIGASSKAKYRKTEVDASHRLSI-FLELVEVHCLNGEQXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---XXXXXXXX
XXXXXXXXXXXXXXXXXXXXEIAERMPCPRSFLLLGDAYMNIQEXXXXXXXXXXXXXXXX
XXXXXXXXXXKAFVKTHN-SKAITYYEAALKSGQQ

PF00515 // ENSGT00390000005979_0_Domain_9 (876, 925)

NYLYYDLAELLLKLKWYDKAEKVLQ
HALAHEP----------------V

ENSGT00390000005979_0_Linker_9_10 (925, 934)

YTLSALMED

PF00515 // ENSGT00390000005979_0_Domain_10 (934, 959)

GRWQVLLAKVYSKMGRPDDAIASLQQX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXELARLYLAQNDPDACLRHCALLIQSDQDNEAATMMMADLMFRKHDYEQAVFHLQQ
FLERKPDNYMTLSRLIDLL-RRCGKLEDVPRFFLMAEKRSPRAKFE

PF00515 // ENSGT00390000005979_0_Domain_14 (1127, 1153)

PGFHYCKGLYLWYT
GEPNDALRHFNK

ENSGT00390000005979_0_Linker_14_15 (1153, 1301)

ARKDSDWGQNALYNMIEICLNPDNETIGGEVFENLDGDLGSSTEKQES
VQLAVRTAEKLLKELKPQTAEGHVQLRILENYCLVATKQKSNVEQALNTFNEIAASEKDH
IPALLGMATAYMILKQTPRARNHLKRIAKMNWNPIDAEEF

PF00515 // ENSGT00390000005979_0_Domain_15 (1301, 1334)

EKSWLLLADIYIQSAKYDMA
EELLKRCLRHNRX

ENSGT00390000005979_0_Linker_15_16 (1334, 1370)

XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX

PF00515 // ENSGT00390000005979_0_Domain_16 (1370, 1415)

XXXXYKLAFN-
-YLKGKKY---------VDAIDVCHQ-VLEAHPTYPKIRKDILDKARASLRP

------------------------------------------------------------
------------TLINYYCQERFFH-HVVIVASEGLKRY-VGDPVFRFYHAYGSLMEGRN
QDAVRELEAXXNKQDVSLCSLIALIYAHKMSSNP---DREAILELDAKMKEHRKTAGPKT
LYYAGLFLWHIGRNDKAREYIDRMIRISN-GSKEGLVLRAWLDVTSGKEAYAKKALRYFD
EGIQEGNDIFALLGKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXX--------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXATNKLGDLISTLDAVE
PQNAQLFYTMAL-FSRTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXIIRCQLIEGHLQDADHQLEFLNEIQQSIGKSAXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLPLGVQYFEKLNPDFLLEIITEYLNFCPA
QPASPGQPPSPLLRQCVSVLETIVRTVPGL

PF00515 // ENSGT00390000005979_0_Domain_4 (571, 608)

LQAFFLIAKVKYLS---GNI-EASQSNLKH
CLKHNPSYADAHLLMAQVYLSQDNFKMCSQSLELCLSYSFEVREYPLYHLIKAQLQKKMG
QIAEAVKTLHMAMSLPGMRRIGASKSKSHQKSEVDASHRLSI-FLELVDAHRLNGEQHEA
AKVLQDAINEFSGTPEELRVTIANADLVLAQGEVERALSMLRNVTPEQPYFVETKEKMAD
IYLKHRKEKKLYVSCYRDL---VEKLPNPHTFLLLGDAYMNIQEPEEAIEAYEQALKQNP
KDGTLASKIGKALVKTHNYSKAITYYEAALKSGQQNF

PF00515 // ENSGT00390000005979_0_Domain_9 (878, 925)

LCYDLAELLLKLKRYEKAEKVLQ
HALAHEP----------------V

ENSGT00390000005979_0_Linker_9_10 (925, 934)

NELSALVED

PF00515 // ENSGT00390000005979_0_Domain_10 (934, 967)

GRYQVLLAKIYSKMEKPAEAIAALQQA
RELQAR

ENSGT00390000005979_0_Linker_10_11 (967, 987)

VLKRVQMEQPDAVPTQKQLA

PF00515 // ENSGT00390000005979_0_Domain_11 (987, 1020)

AEICAEIAKHSAAQRDYEKSIKFYKEALVYCETD
NKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX

PF07719 // ENSGT00390000005979_0_Domain_13 (1055, 1088)

XXXXXMMADLMFRKQEYEQAVFHFQQ
LLERKPDNYTTLSRLIDLL-RRAGKLEDVPRFLLMAEKHNARAKFEPGFNYCRGLYLWYT
GEPNDALRHFNKARKDSDWGQNAIYNMIEICLNPDNETVGGEVFENLDGDLGNSTEKQES
VQLAVRTAEKLLKELKPQTVQGHIQLRIMENYCLMATKQKANVERALNTFTEIATSE---
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------

------------------------------------------------------------
--------QYLKTLINYYCKEKYFH-HMLLVANEGIRRY-ASDLVFRFYHAYGTLMEGKI
QEALREFEALKNKQDVCLCSLLALVYAHKMSPNP---DREAILESDARLKDQRKGAGQKA
LYYAGLFLWHTGRLDKAREYIDRMIKITD-GSKEGQVLKAWLDVTRGKEPYTKKALRCFE
EVLEDGNDLFALLGKAECLELRQNYSGALDTVNQIIVNFPSFLPAFIKKMKLQLALQDWD
QTVETAQRLLLQDNQNVEALRMLALYYLCREGDIEKA--------SAKLENLENALDAME
PHNDQLFYSITLAFSRTCGRNQLILQKIQTFLERAFNLDSQQSEFATELGYQMILQGKVK
EASQWYKIAMTLNESSISSLFGFIQCQLIEGQIEEADQQLEFFTEVQQSIGKSAELTYLH
AILAMKKNKRQEVVISLLNDVLDIHFSHLEDLPLGIQYFEMLNPDFLLEIVKEYLNFCPM
QPTSPGQPVTPLLRRCTSALEIIVRTVPGLLQAVFLIAKVKYLS---GDI-EAAYNNLQH
CLERNPSYADAHLLMAQVYLSQEKFKLCSQSLELCLSYNFKVREYPLYHLIKAQSQKKMG
EITEAIKTLHMAMNLPGMRRIGASSKAKYKKNEVDTSHRLSI-FLELVDVHRLNGEQHEA
AKVLQDAIHEFSGTSEELRVTIANADLALAQGDTERALSMLRNVTTEQPYFVEAKEKMAD
IYLKHRKEKMLYITCYREI---AERMPNPR

PF00515 // ENSGT00390000005979_0_Domain_9 (811, 842)

SFLLLGDAYMNIQEPEEAIVAYEQALNQNP
KDGTLASKIGKALVKTHNYSKAITYYEAALKSGQQNYLCYDLAELLLKLKWYDKAEKVLQ
HALAHES----------------VNELSALMEDGRSQVLLAKVYSKMERPGDAITSLQQA
RELQARVLKRVQMEQPDAVPAQKHLAAEICAEIAKHSVAQRDSETAIKFYREALVHCETD
NKIMLELARLYLAQDDLDACQRHCELLLQSDQDNEPATMMMADIMFRKQDYEQAVYHLQQ
LLERKPDNYMTLSRLIDLL-RRCGKLEDVPRFFLMAEKHNPRSKLEPGFQYCKGLYLWYT
GEPNDALRHFNKARKDSDWGQNALYNMIEICLNPDNETIGGEVFENLDGDLGNSSEKQES
VQLAVRTAEKLLKELKPQTAQGHVQLRIMENCCLMATKQKSNVEQALNTFTEIATSEKDH
IPALLGMATAYMILKQTPRARNQLKRIAKMNWNPIDAEEFEKSWLLLADIYIQSAKYDMA
EELLKRCLRHNRSCCKAYEYMGYIMEKEQAYADAALNYEMAWRHGNQMNPAIGYKLAFN-
-YLKAKKY---------VDAIDVCHQ-VLEAHPSYPKIRKDILDKARTSLRP

------------------------------------------------------------
-----PNDQFSQALINYYCQEKYFH-HVQMCANEGLKDY-GNDPVFLFFRAFGMLMEDEI
QESIRELEAIKDKTDVSLCSLMALIYAHKKSSHP---DREAIQELDSKMKELRKTAGHRG
LYFAGLFLWHVGRHDKAREYIDRMIKISN-GSKEGLVLKAWLDLTCGREAYAKKALKYLE
EGLADGTD

PF00515 // ENSGT00390000005979_0_Domain_1 (249, 282)

VFAMLGKAHYLEMRQNYSEALEVINRILVHCPGFIPALIKKMKLQLALQDWE
QTVETALRLLQKDSHNLEALRMLALHYLCREGNVHEA--------STKLGDLIRALDQFE
PQNAHLYYNMSLAFSRMCERNPLILQQTQTLVERAVNMAAND

PF07719 // ENSGT00390000005979_0_Domain_3 (403, 436)

AEIATELGYQFILQGKVR
EALKWYKTAMSLDETSVSALTGIIRCQLIEGQLQDADQQLEFLMEIQQSIGKSGELSYLR
AVLAMKKQKKQEEVIHLLNDVLDTHFSSLHGLPLGIQYFEKLNPDFLLEIVREYLSFCPT
QPSTPGQPVSPLLRHCASVLEAIMKTAPGLQQAAFLIAKVKYLSV-LGDI-DAAQNSLQH
CLDQNPSYADAHLLMSQIYLFQDNLKLCSQSLELCLSYSFEIRDYPLYNLIKAQTQKRMG
EVQEAIKTLQIAMSLPGMRRAGTSVKSKGKKPEVSPSDRVSI-FLELVDAHRLNGEQHEA
TKVLQDAIIEFSGTPEELRLMIANAELALVHGDVEEALSMLRNVSPEQPYFVQAKEKMAE
IYLKHRKDKKLYVSCYRDL---VDKLPSSHTYLLLGDAYMNIQEPEKAIEIYEQALKKNP
KD

PF00515 // ENSGT00390000005979_0_Domain_9 (843, 876)

GTLASKIGKALIKTHNYSKAISYYEAALKSGQQSFLRYDLAELLLRLKQYDKAEKVLQ
QALDHEA----------------VNELSSLMDD

PF00515 // ENSGT00390000005979_0_Domain_10 (934, 967)

SRYHVLLAKIYSKMEKIDDSIVSLQRA
RELQAR

ENSGT00390000005979_0_Linker_10_11 (967, 987)

VLKRTQMEQPDAVPAQKALA

PF07719 // ENSGT00390000005979_0_Domain_11 (987, 1020)

AEICAEIAKHSTVQRDYEKAIKFYKEALVYCETD
NKVMLELAHLYLAQDDTESCQQQCALLLKIDQDN

PF00515 // ENSGT00390000005979_0_Domain_13 (1055, 1088)

EAATMMMADLMFRKQDYEQAVFHFQQ
LLERKPDNYATLSRLIDLL-RRAGKLEEIPKFLELAEKNSPRAKLEPGFHYCNGLYLWYT
GDPNDALRHFNKARKDSDWGQNAIYNMIEICLNPDNETVGGEVFDNLDGDVGNSTEKQES
VQLAVRTAEKLLKELKPQTLQGHIQLRIMENYCLMATKQKANVERALNTFTEVATAEKDH
IPALLGMATAYMILKQTPKARNQLKRISKMNWNPIDAEEF

PF00515 // ENSGT00390000005979_0_Domain_15 (1301, 1334)

EKGWLLLADIYIQSGKYDMA
GELLKRCLRHNRS

ENSGT00390000005979_0_Linker_15_16 (1334, 1370)

CCKAYEYTGYIMEKEQAYKDAASNYEMAWKYGNQTS

PF00515 // ENSGT00390000005979_0_Domain_16 (1370, 1415)

PTVGYKLAFN-
-YLKAKRY---------VDAIDVCHK-VLELHPNYPKIRKDILDKSRAALRA

------------------------------------------------------------
-----MDSQGLKTLINYYCQERYYH-HVLLVASEGMKKY-SNDPVFRFYHAYGTLMEGKA
QEALREFEAIKNKQDVSLCSLMALMYVHKMSPNP---DREAILELDTKMKEQRKEAGRKA
LYHAGLFLWHIGRHDKAREYIDRMSKMPH-DSNEGPILKAWLDITRGKEPYAKKALRYFE
EGLQDGNDIFALLGKVLCLEIRQNYSGALETVSQIIVNFPSFLPAFEKKMKLQLALQDWD
QTVETAQRLLLQDNHNVEALRMLALYYLCREGDIEKA--------ATKLENLGNALDVME
PQNAELFYKITLAFSRTCGRNQLILQKVQSFLEKAFSLTPQQAEIATELGYQMILQGKVK
EAWKWYRTAMTLNESNISAVTGLIRCQLIEGQLQDADQQLEFFSEFQQSMGKSAELMYLH
AVLATKKNNRQDEVINLLNDVVNTHFSHLEDLPLGIQYFEKLNPDFLLEVVTEYLNLCPI
QPAGPGQPLSPVLRRCSSVLETIIRSVPGLPQAVFLMAKVKYLS---GDT-EAAYNNLQH
CLEHSPSYAEAHLLMAQVYLSQDKVKLCSQSLELCLSYNFNVREYPLYHLIKAQSQKKMG
EVAEAIKTLHMAMNLPGMRRSRASSKSK-HRTEVDASHRLSI-FLELVEVHRLNGEQHEA
AKVLQDAIHEFSGTCEELRVTIANADLALAQGDTDRALSMLRNVTTEQPYFIEAKEKMAD
IYLKHRKEKMLYITCYREI---AERMPSPRSFLLLGDAYMNIQEPEEAIVAYEQALNQNP
KDGTLARKIGKALVKT

PF14559 // ENSGT00390000005979_0_Domain_9 (857, 931)

HNYSKAITYYEAALKSGQQNCLCYDLAELLLRLKLYEKAEKVLQ
HSLAHDP----------------VSELSALMVDGRSQVLLAKVYSKMERPNDAIAALQQA
RELQARILKRVQMEQPDAVPSQKHFAAEICAEIAKHAAAQRDYEKAITFYREALVHCETD
SKIMLELAQLYLAQEDLDASLRHCALLLQRDQDNEPATM

PF13174 // ENSGT00390000005979_0_Domain_13 (1060, 1087)

LMADLMFRKQDYEQAVYHLQQ
LLDRKPDNFMTLSRLIDLL-RRCGKLEDVPRFFLMAEKHNSRTKLEPGFQYCKGLHFWYT
GEPNDALRHFNKARKDSDWGQNALYNMIEICLNPDNETIGGEVFENLNGDLGTSPEKQES
VQLAVRTAEKLLKELKPQTVQGRLQLRIMENCCLMATKQKSSVEQALNTFTEIAASEKDH
IPALLGMATAYMILKQTPKARNQLKRIAKMPWNPIEAEDLE

PF13181 // ENSGT00390000005979_0_Domain_15 (1302, 1328)

KSWLLLADIYIQSAKYDMA
EELLKRCLCHNRSCCKAYEYMGYIMEKEQAYTDAAFNYEMAWKHSNQTNPAVGYKLAFN-
-YLKAKRY---------VDAIDVCHQ-VLEAHPTYPKIRKDILDKARASLRP

------------------------------------------------------------
-----MDSQELKTLINYYCQERYFH-HVLLVASEGIKRY-GSDPVFRFYHAYGTLMEGKT
QEALREFEAIKNKQDVSLCSLLALIYAHKMSPNP---DREAILESDARVKEQRKGAGEKA
LYHAGLFLWHIGRHDKAREYIDRMIKISD-GSKQGHVLKAWLDITRGKEPYTKKALKYFE
EGLQDGNDTFALLGKAQCLEMRQNYSGALETVNQIIVNFPSFLPAFVKKMKLQLALQDWD
QTVETAQRLLLQDSQNVEALRMQALYYVCREGDIEKA--------STKLENLGNTLDAME
PQNAQLFYNITLAFSRTCGRSQLILQKIQTLLERAFSLNPQQSEFATELGYQMILQGRVK
EALKWYKTAMTLDETSVSALVGFIQCQLIEGQLQDADQQLEFLNEIQQSIGKSAELIYLH
AVLAMKKNKRQEEVINLLNDVLDTHFSQLEGLPLGIQYFEKLNPDFLLEIVMEYLSFCPM
QPASPGQPLCPLLRRCISVLETVVRTVPGLLQTVFLIAKVKYLS---GDI-EAAFNNLQH
CLEHNPSYADAHLLLAQVYLSQEKVKLCSQSLELCLSYDFKVRDYPLYHLIKAQSQKKMG
EIADAIKTLHMAMSLPGMKRIGASTKSKDRKTEVDTSHRLSI-FLELIDVHRLNGEQHEA
TKVLQDAIHEFSGTSEEVRVTIANADLALAQGDIERALSILQNVTAEQPYFIEAREKMAD
IYLKHRKDKMLYITCFREI---AERMANP

PF13181 // ENSGT00390000005979_0_Domain_9 (810, 842)

RSFLLLGDAYMNILEPEEAIVAYEQALNQNP
KDGTLASKMGKALIKTHNYSMAITYYEAALKTGQKNYLCYDLAELLLKLKWYDKAEKVLQ
HALAHEP----------------VNELSALMEDGRCQVLLAKVYSKMEKLGDAITALQQA
RELQARVLKRVQMEQPDAVPAQKHLAAEICAEIAKHS

PF14559 // ENSGT00390000005979_0_Domain_12 (998, 1064)

VAQRDYEKAIKFYREALVHCETD
NKIMLELARLYLAQDDPDSCLRQCALLLQSDQDNEAATMMMADLMFRKQDYEQAVFHLQQ
LLERKPDNYMTLSRLIDLL-RRCGKLEDVPRFFSMAEKRNSRAKLEPGFQYCKGLYLWYT
GEPNDALRHFNKARKDRDWGQNALYNMIEICLNPDNETVGGEVFENLDGDLGNSTEKQES
VQLAVRTAEKLLKELKPQTVQGHVQLRIMENYCLMATKQKSNVEQALNTFTEIAASEKEH
IPALLGMATAYMILKQTPRARNQLKRIAKMNWNAIDAEEFE

PF13181 // ENSGT00390000005979_0_Domain_15 (1302, 1329)

KSWLLLADIYIQSAKYDMA
EDLLKRCLRHNRSCCKAYEYMGYIMEKEQAYTDAALNYEMAWKYSNRTNPAVGYKLAFN-
-YLKAKRY---------VDSIDICHQ-VLEAHPTYPKIRKDILDKARASLRP

------------------------------------------------------------
-----MDSKGLKTLINYYCQERYFH-HVVLVASEGMKRY-GSDPVFRFYHAYGTLMEGKI
QEALREFEAIKNKQDVSLCSLIALIYAHKMSPNP---DREAILESDARVKEQRKGADQKA
LYYAGLFLWHIGRHDKAREYIERMIKMPN-SSNEGQILKAWLDIARGNEPYAKKALKYFK
EILQDEKDIFALLGKARCLEMLQNYSGALETVNQIIVNFPSFLPAFIKKMKLQLALQDWD
QMVETAQRLLLQDNQNVEALRMLALYYLCREGNVEKA--------ATTLEHLGNALDVME
PQNAELFYKVTKAFSRTCGRNQLILQKVQTLLEKAFTLSPQQSEFAAEIGYQMILQGKVK
EALTWYQTAMTLDNTSISALTGFIRSQLMDGQLQEADQQLEFLSEVQQSIEKSTELIYLH
VILAMKKNKQQEEVIHLLNDVLDTHFLQLEDVPLSIQYFETLNPDFLLEIITEYLNFCPM
LPASPGQALAPFFRRCTLVLETIVRTVPGLLQAVFLIAKVKYLS---GNI-EAAFNNLQY
CLDHNPSYADAHLLMAQVYLSQEKFKQCSQSLELCLSYNFDVREYPLYHLIKAQSQKKMG
EITEAVKTLHMAMNLPGMRRTGASSKSQGRKTEVDAAHRLSI-FLELVEVHRLNGEQHEA
AKVLQDAIHEFSGTSEELRVTIANADLALAQGDAEQALRILRNVTAEQPYFIEAKEKMAD
IYLKHRKEKMLYITCYREI---AERMPSP

PF13181 // ENSGT00390000005979_0_Domain_9 (810, 842)

RSFLLLGDAYMNIQEPEEAIVAYEQALSQNP
KDGTLASKIGKALVKTHNYSKAITYYEAALKSGQQNYLCYDLAELLLKLKLYEKAEKVLQ
HALAHEP----------------VNELSALMEDGRSQVLLAKVYNKMERPGDAVTALQQA
RELQARILKRVQMEQPDAVPAQKHLAAEICAEIAKHS

PF14559 // ENSGT00390000005979_0_Domain_12 (998, 1063)

VAQQDYEKAIMFYREALVHCETD
NKIMLELARLYLAQGDPDACLRHCMMLLQSDQDNEAATMMMADIMFRKQDYEQAVFHLQQ
LLERKPDNYMTLSRLIDLL-RRCGKFDDIPRFFVMAEKRNPRAKLEPGFQYCKGLYLWYT
GEPNDALRHFNKARKDSEWGQNALYNMIEICLNPDNETIGGEVFENLDGDLGNSTEKQES
VQLAVRTAEKLLKELKPQTIQGHVQLRIMENYCLMATKQKSNVEQALNTFTEIAKSENDH
IPALLGMATAYMILKQTPKARNQLKRIAKMNWNAIDAEEFE

PF13181 // ENSGT00390000005979_0_Domain_15 (1302, 1329)

KSWLLLADIYIQSAKYDMA
EDLLRQCLRHNRSCCKAYEYMGYIMEKEQAYSDAASNYEMAWKYGNQTNPAVGYRLAFN-
-YLKAKRYV---------DAIDICHQ-VLEAHPTYPKIRKDILDKARASLRP

------------------------------------------------------------
-----MDSKGLQTLINYYCQERYFH-HVSLVASEGMKRY-GSEPVFRFYHAYGTLMEGKI
QEALREFEAIKNKQDVSLCSLIALIYAHKMSPSP---DREAILESDARVKEQRKGADQ

PF13181 // ENSGT00390000005979_0_Domain_0 (179, 207)

KA
LYHAGLFLWHIGRHDKAREYIERMIKMPN-SSNEGQILKAWLDITRGKEPYAKKALKCFE
EGLQDGKDIFALLGKVQCLEMRQNYSGALETVNQIIVSFPSFLPAFIKRMKLQLALQDWD
QMVETAQRLLLQDNQNVEALRMLAVYYLCREGNIEKA--------TTKLENLGNALDVME
PQNAQLFYKITKVFSRTCGRNELILQKVQTLLEKAFSLNPQSSEFAAEIGYQMILQGKIK
EALTWYQTAMTLDNTSISALTGFIRCQLMDGQLQEADQQLEFLSEVQQSMEKSAELIYLN
AVLAVKKNKRSEEVIHLLNDVLDTHFLHLEDLPLGIQYFEALNPDFLLEIVAEYLNFCPM
MPASPGQPLAPFLVRCTWVLETVVRTVPGLLQAVFLIAKAKYLS---GNI-EAAFNNLQH
CLDHNPSYADAHLLMAQVYLSQEKFKLCSQSLELCLSYNFNVREYPLYHLIKAQAQKKMG
EVTEAIKTLHMAMNLPGMRRTGASSKSKYRKSEVDASHRLSV-FLELVEVHRLNGEQHEA
AKVLQDAIHEFSGTSEELRVTIANADLALAQGDVERALSILRNVTAEQPYFIEAKEKMAD
IYLKHRKEKMLYITCYREI---AERMPSPRSF

PF07719 // ENSGT00390000005979_0_Domain_9 (813, 842)

LLLGDAYMNIQEPEEAIIAYERALNLNP
KDGTLASKIGKALVKTHNYSKAITYYEAALKNGQQNYLCYDLAELLLKLKLYEKAEKVLQ
HALAHEP----------------VNEPSALMEDGHSQVLLAKVYSKMERPGNAVTSLQQA
RELQARVLKRVQMEQPDAVPAQKHLAAEICAEIAKHS

PF14559 // ENSGT00390000005979_0_Domain_12 (998, 1063)

VAQQDYEKAIMFYREALVHCETD
NKIMLELARLYLAQGDPDACLRHCMMLLQSDQDNEAATMMMADIMFRKQDYEQAVFHLQQ
LLERKPDNYMTLSRLIDLL-RRCGKFDDVPRFFVMAEKHNSRAKLEPGFQYCKGLYLWYT
GEPNDALRHFNKARKDSEWGQNALYNMIEICLNPDNETVGGEVFENLDGDLGNSTEKQES
VQLAVRTAEKLLKELKPQTVQGHVQLRIMENYCLMATKQKPNVEQALSTFTEVAKSENDH
IPALLGMATAYMILKQTPKARNQLKRIAKMNWNAIDAEEFE

PF13181 // ENSGT00390000005979_0_Domain_15 (1302, 1329)

KSWLLLADIYIQSAKYDMA
EDLLRQCLRHNRSCCKAYEYMGYIMEKEQAYSDAASNYEMAWKYGNQANPAVGYRLAFN-
-YLKAKRY---------VDAIDICHQ-VLETHPTYPKIRKDILDKARASLKP

MVTASREGVPAPSPMNIRPVPTLTVFLPVSLPPPFSGSQWQRAAGLFPSPSGGLRWWRWL
ATAEAMDAAVQQALLNYYCQECYFH-HVRAAAEEALGRL-GSDPVFQFYRAYGALRTGDV
QESIRQLESIKNKQEVSLCAMMALIYAHKKSPNP---DRDAILELDTKLKEQRKTAGQQA
LYFAGLFLWHLGREDKAREYVDRVIKVSN-GDKEGLILKAWLDLTCGKETHIKKALKYFD
EALQEGNDVFALLGKAQYFEIRQNYSGALEMVNQIIANFPNFIPAFIKKMKLQLALQDWE
QAVETAHRLLQKDALNLEATRMEALHFLCREGKMREA--------SARLSDLIKALDRLE
PRNSQLFYKMALAFSRTCGRNQLILQHTQTLVERAFNLDSDNAEFATELGYQMILQGKVK
EALKWYQTAMTLDETSVSALTGIIRCQLIQGQLEDAEQQLEFLNEIQQSIGKSGELSFLR
AVLAMKKHKRQEEVIALLNDVLDTHFSALHGFPLGVEYFEKLNPDFLLEIIREYLNFCPA
EPASPGQSPSPLLKHCASVLETVVKTVPGLQQAVFLIAKVKYLS--

PF14559 // ENSGT00390000005979_0_Domain_5 (587, 630)

-GDI-EAAHTNLRY
CLERDPSYADAHLLMAQVYLAQNNPKLCSQSLELCLSYNFEVREHPVYHLIKAQTQKKMG
ELSEAIKTLQMARNLPGMRKHTASSKMKGKRIEIDASDRVAV-FLELVEAHCLNGEPHEA
AVVLQDAIDEFSGTPEEL

PF07721 // ENSGT00390000005979_0_Domain_8 (739, 762)

RVMIANADLEIAQGDIEQALAML

ENSGT00390000005979_0_Linker_8_9 (762, 813)

RSITPEQPYFVQAKLKMAD
IYLQCRRDKKSYAACYRDL---VEKLPSAHTF

PF13432 // ENSGT00390000005979_0_Domain_9 (813, 875)

LLLGDAYMNIQEPDEAIEVYEQALKKNP
KDPALASKIGKALIKTHNYSKAISYYEAALKSGQQNFLYYDLAELLMKLKQYEKAEVVLQ
QALDHEYVYNCAQDITFTNRRTYINELSSLMEDGR

PF13181 // ENSGT00390000005979_0_Domain_10 (936, 963)

YQVLLAKIYSKMEKIDEAITSLQQA
RELQARVLKRAQTEQPDAVPAQKQLAAEICAEIAKHCTVQRNYEKAIKFYKEALVHCETD
KKAMLELARLYLAQDDSDACQHQCSLLLRSEQDNEAAT

PF13174 // ENSGT00390000005979_0_Domain_13 (1059, 1087)

MMMADLMFRKQDYEQAVFHFQQ
LLERKPDNYATLSRLIDLL-RRAGKLEEVPRFLLMAEKHSSRAKLEPGFHYCKGLYLWYT
GEPNDALRHFNKARKDNDWGQNAVYNMIEICLNPDNETIGGEVFENLDADIGNSTEKQES
VQLAVRTAENLLKELKPQTIQGHIQLRIMENYCLMATKQKSNVERALNTFTEIVVAEKDH
IPALLGMATAYMILKQTPRARNQLKRISKMNWNPIDAEEFE

PF13181 // ENSGT00390000005979_0_Domain_15 (1302, 1329)

KSWLLLADIYIQSSKYDTA
GELLKQCLRHNKSCCKAYEYMGYIMEKEQAYKDAAINYEMAWRYGNQSNPTIGYKLAFN-
-YLKGKRY---------VDAIAICHK-VLEAHPNYPKIRKEILDKARASLRA

------------------------------------------------------------
-----MDSQELKTLINYYCQERYFH-HVSLVASEGIKRY-GSDPVFRFYHAYGTLMEGKT
QEALREFEAIKNKQDVSLCSLIALIYAHKMSPNP---DREAILESDARVKEQRKGAGEKA
LYHAGLFLWHVGRHDKAREYIDRMIKMSD-GSKQGHILKAWLDITRGKDAYTKKALKYFE
EGLQDGNDTFALLGKAQCLEMRQNYSGALETVNQIIVNFPSFLPAFIKKMKLQLALQDWD
QTVETAQRLLLQDSQNVEALRMQALYYVCREGDIEKA--------STKLENLGNALDAME
PQNAQLFYNTTLAFSRTCGRSQLILQKIQMLLERAFSLNPQQSEFATELGYQMILQGRVK
EALKWYKTAMTLDETSVPALVGLIQCQLIEGQLQDADQQLEFLNEIQQSIGKSAELIYLH
AVLAMKKNKQQEDVINILNDVLDTHFSQLEGLPLGIQYFEKLNPDFLLEIVTEYLSFCPM
QPASPGQPLCPLLRRCVSVLETVVRTVPGLLQTVFLIAKVKYLS---GDI-EAAFNNLQH
CLEHNPSYADAHLLLAQVYLSQEKIKLCSQSLELCLSYDFKVREYPLYHLIKAQSQKKMG
EIADAIKTLHMAMSLPGMKRIGASTKSKDRKTQVDTSHRLSI-FLELIEVHRLNGEQHEA
AKVLQDAIHEFSGTSEEVRVTIANADLALAQGDTERALSILRNVTSEQPYFIEAREKMAD
IYLKQRKDKMLYITCYREI---AERMPNP

PF13181 // ENSGT00390000005979_0_Domain_9 (810, 842)

RSFLLLGDAYMNILEPEEAIVAYEQALNQNP
KDGTLASKMGKALIKTHNYSMAISYYEAALKSGQKNYLCYDLAELLLKLKWYDKAEKVLQ
QALAHEL----------------VNELSALMEDGRCQVLLAKVYSKMERPSDAITALQQA
RELQARVLKRVQMEQPDAVPAQKRLAAEICAEIAKHS

PF14559 // ENSGT00390000005979_0_Domain_12 (998, 1064)

VAQRDYEKAIKFYREALVHCETD
NKIMLELARLYLAQDDPDACLRQCAVLLQSDQDNEAATTMMADLMFRKQDYEQAVFHLQQ
LLERKPDNYMTLSRLIDLL-RRCGKLEDVPRFFSMAEKCNSRVKLEPGFQYCKGLYLWYT
GEPNDALRHFNKARKDSDWGQNALYNMIEICLNPDNETIGGEVFENLDGDLGNSTERQES
VQLAVRTAEKLLKELKPQTVQGQVQLRVMENYCLMATKQKSNVEQALNTFTEIAASEKDH
IPALLGMATAYMILKQTPRARNQLKRIAKMNWNAIDAEEFE

PF13181 // ENSGT00390000005979_0_Domain_15 (1302, 1329)

KSWLLLADIYIQSAKYDMA
EELLKRCLRHNRSCCKAYEYMGYIMEKEQAYTDAALNYEMAWKYSNQTNPAVGYKLAFN-
-YLKAKRY---------VDSIDICHQ-VLEAHPTYPKIRKDILDKARASLRP

------------------------------------------------------------
-----MDSQGLKTLINYYCQEKYFH-HVLMIASEGMKRY-GTDPVFKFYHAYATLMEGKT
QEALREFESIKNKQDVSLCSLLALMFTHKLSSNP---DREAILELDGRVKEQRKEAGQKT
LYHAGLFLWHIGRHDKAREYIDRMLKLPN-DNNEGQVLKAWLDITKGKEPYTKKALRSFE
EGLQDGNDIFALLGKVQCLEVRQNYSGALETVNQIIVNFPTFLPAFEKKMKLQLALQDWD
QTVETAQRLLLQDSQNVEALRMLALYYLCREGDMEKA--------STKLEHLGNALNTME
PQNAQLFYKITLAFSRTCGRNPLILQKIQTFLDRAFNLAPHQPEIATELGYQMIFQGKVK
EAWRWYKTAMTLNETSISAVTGLIRCQLIEGQLEDADQQLEFFSEFQQSMGKCAELIYLH
AVLAMQKNKRQEEVINLLDDVLDTHFSNLEELPLGVQYFEKLNPDFLLEVIIEYLNFCPM
QPSSPGQPLSPLLRRCTSVLETIVRTVPGLLQAVFLIAKVKYLS---GDI-EAAYNNLQH
CLEHNPSYAEAHLLMAQVYLSQEKFKLCSQSLELCLSYNFDVREYPLYHLIKAQSQKKMG
EISEAITTLHMAMNLPGMRRTGTSSK--SRKTDVDRSNRLSI-FLELVEVHRLNGEQHEA
AKVLQDAIHEFSGTSEELRVTIANADLALAQGDTEQALNMLRNVTAEQPYFIETKEKMAD
IYLKYRKEKMLYITCYREI---AERMPSP

PF13181 // ENSGT00390000005979_0_Domain_9 (810, 842)

RSFLLLGDAYMNIQEPEEAIVAYEQALNQNP
KDGTLASKIGKALVKTHNYFKAITYYEAALKSGQQNYLCYDLAELLLKLKWYEKAEKVLQ
HALSHEP----------------VNELSTLMEDGRSQVLLAKVYSKMERPGEAVISLQQA
RELQTRILKRVQMEQPDAVPAQKHLAAEICAEIAKHS

PF14559 // ENSGT00390000005979_0_Domain_12 (998, 1063)

VAQRDYENAIKFYKEALIHCETD
NKIMLELARLYLAQDDPEASMRHCSQLLQNDQDNEPATMMMADLMFRKQDYEQAVFHLQQ
LLERKPDNYMTLSRLIDLL-RRCGKLHDVPRFFSMAEKFNSRAKLEPGFQYCNGLHLWYT
GEPNDALRHFNKARKDSDWGQNAIYNMIEICLNPDNETIGGEVFENLDGDLGNSTEKQES
VQLAVRTAEKLLKELKPHTAQGHVQLRIMENYCLMATKQKANVEQALNAFTEIATVEKDH
IPALLGMATAYMILKQTPRARNQLKRISKMIWNPIDAEEFE

PF13181 // ENSGT00390000005979_0_Domain_15 (1302, 1329)

KSWLLLADIYIQSAKYDMA
EELLKRCLRHNRSCCKAYEYMGYIMEKEQAYSDAAFNYEMAWKHSNQTNPSVGYKLAFN-
-YLKAKRY---------VDSIDICHQ-VLKAHPAYPKIRKEILDKARSSLRP

------------------------------------------------------------
-----MDAQRLKALINYYCQERYYH-HVLLVASEGMKKY-GSDPVFRFYHAYGTLMEGKT
QEALREFEAIKNKQDVSLCSLIALMYVHKMSPNP---DREAILELDTKMKEQRKEAGRKA
LYHAGLFLWHIGRHDKAREYIDRMSKMPH-DGNEGPILKAWLDITRRKEPYAKKALRYFE
EGLQDGNDIFALLGKVLCLEMRQNYSGALETVSQIIVNFPNFLPAFEKKMKLQLALQDWD
QTVETAQRLLLQDSNNVEALRMLALYYLCREGDIEKA--------ASKLENLASALDVVE
PQNAQLFYKITIAFSRTCGRNQLILQKVQGFLEKAFSLTPQQAEIATELGYQMILQDKVK
EAWKWYRIAMTLNESNISAVTGLIRCQLMEGQLQDAAQQLEFFSEFQQSMGKSAELMYLH
AVLATKKNNRQEEVINLLDDVVNTHLSHLEDLPLGIQYFEKLNPDFLLEVVTEYLNFCPI
QPAGPGQPVSPVLRHCSSVLETIIRSVPGLPQAVFLMAKVKYLS---GDT-EAAYNNLQH
CLERSPSHAEAHLLMAQVYLSQEKVKLCSQALELCLSYNFNVRDYPLYHLIKAQSQKKMG
EVAEAIKTLHMAMNLPGMRKSRASSKSK-HRTEVDASHRLSI-FLELVEVHRLNGEQHEA
AKVLQDAIHEFSGTCEELRVTIANADLALAQGDTERALNMLRNVTTDQPYFTEAKEKMAD
IYLKHRKEKMLYITCYREI---AERIPSPRSFLLLGDAYMNIQEPEEAIVAYEQALNQNP
KDGTLARK

PF13432 // ENSGT00390000005979_0_Domain_9 (849, 905)

IGKALVKTHNYSKAITYYEAALKSGQQNCLCYDLAELLLRLKLYEKAEKVLQ
HSLAHEP----------------VNELSALMEDGRSQVLLAKVYSKMERPSDAIAALQQA
RELQTRILKRVQMEQPDAVPSQKHFAAEICAEIAKHSAAQRDYEKAITSYKEALVHCETD
SKIMLELAQLYLAQEDLDASLRHCALLLQRDQDSEPATMLMADLMFRKQDYEQAVFHLQQ
LLERKPDNFMTLSRLIDLL-RRCGKLEDVPRFFSMAEKYNSRTKLEPGFQYCKGLHFWYT
GEPNDALRHFNKARKDSDWGQNALYNMIEICLNPDNETIGGEVFENLDGDLGSSTEKQES
VQLAVRTAEKLLKELKPQTVQGRLQLRVMENCCLMATKQKSSVEQALNTFTEIAAAEKDH
IPALLGMATAYMILKQTPKARNQLKRIAKMTWNPIEAEDLE

PF13181 // ENSGT00390000005979_0_Domain_15 (1302, 1328)

KSWLLLADIYIQSAKYDMA
EELLKRCLCHNRSCCKAYEYMGYIMEKEQAYTDAAFNYEMAWKHTNQTNPAVGYKLAFN-
-YLKAKRY---------VDAIDICHQ-VLEAHPAYPKIRKDILDKARASLRP

------------------------------------------------------------
-----MDSKGLKTLINYYCQERYFH-HVLLVASEGMKRY-GNDPVFRFYHAYGTLMEGKI
QEALREFEAIKNKQDISLCSLIAVIYAHKMSPNP---DREAILESDARVKEQRKGADQ

PF13181 // ENSGT00390000005979_0_Domain_0 (179, 208)

KA
LYHAGLFLWHLGRHDKAREYIERVIKMPN-NSNEGQILKAWLDITRGKEPYAKKALRCFE
EGLQDGKDIFALLGKAQCLEMRQNYSGALEAVNQIIVNFPSFLPAFIKKMKLQLALQDWD
QMVETAQRLLFQDNQNVEALRMLALYCLCREGNVEKA--------TTKLENLGNALDVME
PQNAQLFYKITIAFSRTCGRNQLILQKLQTLLEKAFRLTPQQSEFAAEIGYQMILQGKVK
EALTWYQTAMTLDNTSISALVGFIRCQLMDGQLQEADQQLEFLSEVQQSMEKSTELIYLH
ATLAMKKNKQEEEVIHLLNDVLDTHFSHLEDLPLGIQYFETLNPDFLLEIITEYLNFCPM
LPASPGQPLTPFLRRCMLVLETIVRTVPGLLQAVFLIAKVKYLS---GNI-EAAYSNLQH
CLDHDPSYADAHLLMAQVYLSQEKFKLCSQSLEFCLSYNFNVREYPLYHLIKAQSQKKLG
EITEAIKTLHMAMNLPGVRRTGASSKSKYRKTEVDTSHRLSI-FLELVEVHRLNGEQHEA
AKVLQDAIHEFAGTSEEL

PF07721 // ENSGT00390000005979_0_Domain_8 (739, 762)

RVTIANANLALAQGDVERALSILRNVTAEQAYFIEAKEKMAD
IYLKHRKEKMLYIT----------------------------------------------
---------------------------SALKSGQQNYLCYDLAELLLKLKLDEKAEKVLQ
HALAHEP----------------VNELSALMEDGRSQVLLAKVYSKIGRPGEAVTSLQQA
RELQARVLKRVQMEQPDAVPAQKHLAAEICAEIAKHSVAQQDYEKAIMFYREALVHCETD
NKIM

PF07721 // ENSGT00390000005979_0_Domain_12 (1025, 1043)

LELARLYLAQGDPDACLRHCVMLLQNDQDNESATMMMADIMFRKQDYEQAVFHLQQ
LLERKPDNYMTLSRLIDLL-RRCGKFDDIPRFFVMAEKHNSRAKLEPGFQYCKGLYLWYT
GEPNDALRHFNKARKDSEWGQNALYNMIEICLNPDNETIGGEVFENLDGDLGNSTEKQES
VQLAVRTAEKLLKELKPQTLQGHVQVRIMENYCLMATKQKPNVEQALNTFTEVAKSENDH
IPALLGMATAYMILKQIPKARNQLKRITKMNWNAIDAEDFE

PF13181 // ENSGT00390000005979_0_Domain_15 (1302, 1329)

KSWLLLADIYIQSAKYDMA
EDLLRQCL

ENSGT00390000005979_0_Linker_15_16 (1329, 1348)

RHNRSCCKAYEYMGYIMEK

PF14559 // ENSGT00390000005979_0_Domain_16 (1348, 1416)

EQAYSDAASNYERAWKYGNQTNPAVGYRLAFN-
-YLKAKRY---------VDAIDICHQ-VLETHPTYPKIRKDILDKARASLRP

------------------------------------------------------------
-----MDSQELKTLINYYCQERYFH-HVLLVASEGIKRY-GSDPVFRFYHAYGTLMEGKT
QEALREFEAIKNKQDVSLCSLIALIYAHKMSPNP---DREAILESDARVKEQRKGAGEKA
LYYAGLFLWHIGRHDKAREYIDRMIKMSD-GSKQGHVLKAWLDITRGKDPYTKKALKYFE
EGLQDGNDTFALLGKAQCLEMRQNYSGALETVNQIIVNFPSFLPAFVKKMKLQLALQDWD
QTVETAQRLLLQDSQNVEALRMQALYYVCREGDIEKA--------STKLENLGNALDAME
PQNAQLFYNITLAFSRTCGRSQLILQKIQTLLERAFSLNPQQSEFATELGYQMILQGRVK
EALKWYKTAMTLDETSVSALVGFIQCQLIEGQLQDADQQLEFLNEIQQSIGKSAELIYLH
AVLAMKKNKRQEEVINLLNDVLDTHFSQIEGLPLGIQYFEKLNPDFLLEIVTEYLSFCPM
QPASPGQPLCPLLRRCVSVLETVVRTVPGLLQTVFLIAKVKYLS---GDI-EAAFNNLQH
CLEHNPSYADAHLLLAQVYLSQEKVKLCSQSLELCLSYDFKVREYPLYHLIKAQSQNKMG
EIADAIKTLHMAMSLPGMKRIGASTKSKDRKTEVDTSHRLSI-FLELIELHRLNGEQHEA
AKVLQDAIHEFSGTSEEVRVTIANADLALAQGDIERALSILQNVTAEQPYFIEAREKMAD
IYLKHRKDKMLYITCFREI---AERMANPRSFLLLGDAYMNILEPEEAIVAYEQALNQNP
KDGTLASKMGKALIKTHNYSMAITYYETALKSGQKNY

PF13181 // ENSGT00390000005979_0_Domain_9 (878, 903)

LCYDLAELLLKLKWYDKAEKVLQ
HALAHEP----------------VNELSALMEDGRCQVLLAKVYSKMERPGDAITALQQA
RELQARVLKRVQMEQPDAVPAQKHLAAEICAEIAKHS

PF14559 // ENSGT00390000005979_0_Domain_12 (998, 1064)

VAQRDYEKAIKFYREALVHCETD
NKIMLELARLYLAQDDPDSCLRQCALLLQSDQDNEAATMMMADLMFRKQDYEQAVFHLQQ
LLERKPDNYMTLSRLIDLL-RRCGKLEDVPRFFSMAEKRNSRAKLEPGFQYCKGLYLWYT
GEPNDALRHFNKARKDRDWGQNALYNMIEICLNPDNETIGGEVFENLDGDLGNSTEKQES
VQLAVRTAEKLLKELKPQTVQGHVQLRIMENYCLMATKQKSNVEQALNTFTEIAASEKDH
IPALLGMATAYMILKQTPRARNQLKRIAKMNWNAIDAEEFE

PF13181 // ENSGT00390000005979_0_Domain_15 (1302, 1329)

KSWLLLADIYIQSAKYDMA
EELLKRCLRHNRSCCKAYEYMGYIMEKEQAYTDAALNYEMAWKYSNRTNPAVGYKLAFN-
-YLKAKRY---------VDSIDICHQ-VLEAHPTYPKIRKDILDKARASLRP

------------------------------------------------------------
------------ALINYYCQERYFH-HVLLAASEGTKRY-GSDPIFRFYYAYGTLMEGKT
QEALREFEAIKNKQDVSLCSLIALIYTHKMSPNP---DREAIQESDARVKEQRKGAG

PF00515 // ENSGT00390000005979_0_Domain_0 (178, 212)

PKA
LYHAGLFLWHIGRHDKAREYVDRMIKMSN-G

ENSGT00390000005979_0_Linker_0_1 (212, 249)

SKEGQVLRAWLDITRGKEPYTKKALRYFE
EGLQDGND

PF00515 // ENSGT00390000005979_0_Domain_1 (249, 282)

IFALLGKAQCLEMRQNYSGALETVNQIIMNFPSFLPAFVKKMKLQLALQDWD
QTVETAQRLMLQDNQNVEALRMMALYYLCREGDIEKA--------ATKLENLGNAVDAME
PQNAQLFYNITIAFSRTCGRSQLILQKTQTLLERAFSLTPQQ

PF00515 // ENSGT00390000005979_0_Domain_3 (403, 436)

SEFATELGYQMILQGKVK
EALKWYKTAMTLDETSVSALIGFIQCQLIEGQLQEADQQLEFLSEIQQSIGKSAELTYLH
AVLAMKKNKRQEEVINLLNDVLDTHFSHLEDLPLGIQYFEKLNPDFLLEIITEYLNFCPL
QXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXX---XXDIEAAYNNLQH
CLEHSPSY

PF00515 // ENSGT00390000005979_0_Domain_6 (609, 642)

ADAHLLMAQVYLSQEKFKLCSQSLELCLSYNFKVREYPLYHLIKAQSQKK-G
EIAEAI-TLHIAMSLPGMRRTGTSSKSKYIKTEVDASHRLSV-FLELVEVHRLNGEQHEA
AKVLQDAIHEFSGTSEE

PF07721 // ENSGT00390000005979_0_Domain_8 (738, 763)

LRVTIANADLALAQGDVERALSMLQNVTSEQPYFIETKEKMAD
IYLKHRKEKMLYITCYREI---AERMPSPRSFILLGDAYMNIQEXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXAITYYEAALKNGQQ

PF00515 // ENSGT00390000005979_0_Domain_9 (876, 925)

NYLFYDLAELLLKLKWYDKAEKVLQ
HALAHEP----------------VNELSALTEDGRSQVLLAKVYSKVDRPGDAVASLQQA
RELQARVLKRVQMEQPDAVPAQKHLA

PF00515 // ENSGT00390000005979_0_Domain_11 (987, 1020)

AEICAEIAKHSVAQRDYEKAIKFYREALVHCETD
N-IMLELARLYLAQDDPDACLRHCALLLQSDQDN

PF00515 // ENSGT00390000005979_0_Domain_13 (1055, 1088)

EAATMMMADLMFRRQDYEQAVFHLQQ
LLERKPDNYMTLSRLIDLL-RRCGKLEDVPRFFLMAEKRNSRAKLEPGFQYCKGLYLWYT
GEPNDALRHFNKARKDSDWGQNALYNMIEICLNPDNETIGGEVFENLDGDLGNSTEKQES
VQLAVRTAEKLLKELKPQTVQGHVQLRIMENCCLMATKQKSNVEQALNTFTEIATSEKDH
IPALLGMATAYMILKQTPRARNQLKRIAKMNWNPIDAEDF

PF00515 // ENSGT00390000005979_0_Domain_15 (1301, 1334)

ERSWLLLADIYIQSAKYDMA
EELLKRCLRHNRSCCKAYEYMGYIMEKEQAYTDAALNYEMAWKHGNQTNPAVGYKLAFN-
-YLKAKKF---------VDAIDVCHQ--------------------------

------------------------------------------------------------
-----MDSQELKTLINYYCQERYFH-HVLLVASEGIKRY-GSDPVFRFYHAYGTLMEGKT
QEALREFEAIKNKQDVSLCSLIALIYAHKMSPNP---DREAILESDARVKEQRKGAGEKA
LYHAGLFLWHIGRHDKAREYIDRMIKTSD-GRKQGHVLKAWLDITRGKDPYTKKALKYFE
EGLQDGNDTFALLGKAQCLEMRQNYSGALETVNQIIVNFPSFLPAFVKKMKLQLALQDWD
QTVETAQRLLLQDSQNVEALRMQALYYVCREGDIEKA--------STKLENLGNALDAME
PQNAQLFYNITLAFSRTCGRSQLILQKIQMLLERAFSLNPQQSEFAAELGYQMILQGRIK
EALKWYKTAMTLDETSVSALVGFIQCQLIEGQLQDADQQLEFLNEIQQSIGKSAELIYLH
AVLAMKKNKRQEEVINLLNDVLDTHFSQIEGLPLGIQYFEKLNPDFLLEIVMEYLSFCPM
QPASPGQPLCPLLRRCVSVLETVVRTVPGLLQTVFLIAKVKYLS---GDI-EAAFNNLQH
CLEHNPSYADAHLLLAQVYLSQEKVKLCSQSLELCLSYDFKVREYPLYHLIKAQSQKQMG
EIADAIKTLHMATSLPGMKRIGASTKSKDRKTEVDTSHRLSI-FLELIELHRLNGEQHEA
AKVLQDAIHEFSGTSEEVRVTIANADLALAQGDIERALSILQNVTAEQPYFIEAREKMAD
IYLKHRKDKMLYITCFREI---AERMANPRSFLLLGDAYMNILEPEEAIVAYEQALNQNP
KDGTLASKMGKALIKTHNYSMAITYYETALKSGQKNY

PF13181 // ENSGT00390000005979_0_Domain_9 (878, 903)

LCYDLAELLLKLKWYDKAEKVLQ
HALAHEP----------------VNELSALMEDGRCQVLLAKVYSKMERPGDAITALQQA
RELQARVLKRVQMEQPDAVPAQKHLAAEICAKIAKHS

PF14559 // ENSGT00390000005979_0_Domain_12 (998, 1064)

VAQRDYEKAIKFYREALVHCETD
NKIMLELARLYLAQDDPDSCLRQCALLLQSDQDNEAATMMMADLMFRKQDYEQAVFHLQQ
LLERKPDNYMTLSRLIDLL-RRCGKLEDVPRFFSMAEKRNSRAKLEPGFQYCKGLYLWYT
GEPNDALRHFNKARKDRDWGQNALYNMIEICLNPDNETIGGEVFENLDGDLGNSTEKQES
VQLAVRTAEKLLKELKPQTVQGHVQLRIMENYCLMATKQKSNVEQALNTFTEIAASEKDH
IPALLGMATAYMILKQTPRARNQLKRIAKMNWNAIDAEEFE

PF13181 // ENSGT00390000005979_0_Domain_15 (1302, 1329)

KSWLLLADIYIQSAKYDMA
EELLKRCLRHNRSCCKAYEYMGYIMEKEQAYTDAALNYEMAWKYSNRTNPAVGYKLAFN-
-YLKAKRY---------VDSIDICHQ-VLEAHPTYPKIRKDILDKAHASLRP

------------------------------------------------------------
-----MDSQGLKTLINYYCQERYYH-HVLLVASEGMKKY-SSDPVFRFYHAYGTLMEGKA
QEALREFEAIKNKQDVSLCSLMALMYVHKMSPNP---DREAILELDTKMKEQRKEAGRKA
LYHAGLFLWHIGRHDKAREYIDRMSKMPH-DSNEGPILKAWLDITRGKEPYAKKALRYFE
EGLQDGNDIFALLGKVLCLEMRQNYSGALETVSQIIVNFPSFLPAFEKKMKLQLALQDWD
QTVETAQRLLLQDGHNVEALRMLALYYLCREGDIEKA--------AAKLENLGNALDVME
PQNAQLFYKITIAFSRTGGRKKLILQKVQSFLEKEFSLTPQTETLLVLAGGGALLKGTIE
GMWGLYRTLSTERCTQVSLITAWVQSTRSLGDLGGAGQQADLESAMFQRLLRFTVCFHLI
AYLARKKNSISEWVLSLINFELVTTFNELRSSLISGQVYSKKNTRFFSHISHTKISVCLV
RPAGPGQPLSPVLRRCSSVLETIIRSVPGLPQAVFLMAKVKYLS---GDT-EAAYNNLQH
CLEHSPSYAEAHLLMAQVYLSQDKVQLCSQSLELCLSYNFNVRDYPLYHLIKAQSQKKMG
EVAEAIKTLHMAMNLPGMRRSRASSKSK-HRSEVDGSHRLSI-FLELVEVHRLNGEQHEA
AKVLQDAIHEFSGTCEELRVTIANAERALAQGDTERALRMLRNVTTEQPYFIEAKEKMAD
IYLKHRKEKMLYITCYREI---AERMPSP

PF13181 // ENSGT00390000005979_0_Domain_9 (810, 842)

RSFLLLGDAYMNIQEPEEAIVAYEQALNQNP
KDGTLARKIGKALVKTHNYSKAITYYEAALKSGQQNCLCYDLAELLLRLKLYEKAEKVLQ
HSLAHDP----------------VNELSALMVDGRSQVLLAKVYSKMERPGDAIAALQQA
RELQARILKRVQMEQPDAVPSQRHFAAEICAEIAKHSAAQRDYEKAITFYREALVHCETD
SKIMLELAQLYLAQEDLDASLRHCALLLQRDQDNEPATMLMADLMFRKQDYEQAVFHLQQ
LLERKPDNFMTLSRLIDLL-RRCGKLEEVPRFFLMAEKHNSRTKLEPGFQYCKGLHFWYT
GEPNDALRHFNKARKDSDWGQNALYNMIEICLNPDNETIGGEVFENLNGDLGTSPEKQES
VQLAVRTAEKLLKELKPQTVQGRLQLRIMENCCLMATKQKSSVEQALNTFTEIAASEKDH
IPALLGMATAYMILKQTPKARNQLKRIAKMTWNPIEAEELE

PF13181 // ENSGT00390000005979_0_Domain_15 (1302, 1328)

KSWLLLADIYIQSAKYDMA
EELLKRCLCHNRSCCKAYEYMGYIMEKEQAYTDAAFNYEMAWKHSNQTNPAVGYKLAFN-
-YLKAKRY---------VDAIDVCHQ-VLEAHPTYPKIRKDILDKARASLRP

------------------------------------------------------------
-----MDALGLKTLINYYCQENLFH-HVLIVASDGMKRY-ASDPVFRFYHAYGTLMEGKI
QEALREFEAIKNKQDVSLCSLIALVYAHKMSPNP---DREAILEAEARMKEQRRVAGQDA
LYHAGLFLWHIGRHEKAREYIDRMIKTSSCRTTEGQVLRAWLEITRGKDPNIKKALKYFE
EALQEENDIFALLGKAQCLEMRQNFVGALETLNQITLNFPSFLPALVKKMKLQLTLQEWD
QTVETAQXXXXXXXXXXXXXXXXXXXXX--------XXXXXXXXATSKLESLANTLEAME
PQNAQLFYKITLAFSRTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XPASPGQPLSSFLRRCTSVLEIVVRTVPGLLQAIFLIAKVKYLS---GDM-EAAFNNLQH
CLEQNSSYADAHLLMARVYLSQEKFQLCCQSLELCLSYNFKVREDPLYHLVKAQAQKKMG
EIAEAMKTLHMAMNLPGMRRFGASSTSKGQXXXXXXXXXXXXXXXXXXXXXXXXXXXHEA
AKVLQDAIHEFSGTSEE

PF07721 // ENSGT00390000005979_0_Domain_8 (738, 763)

LRVTMANADLALAQGDIERALSMLRNVTTQQPYFIEAKEKMAD
IYLKYRKEKMLYITCYREM---AERLPCPRSFLLLGDAYMNIQEPEEAIVAYEQALNQNP
KD

PF00515 // ENSGT00390000005979_0_Domain_9 (843, 876)

GTVARKIGKALVKTHNYSKAITYYETALKNGQHNYLACDMAELLLKLKMCERAENVLQ
HALPHEP----------------VNELSALIEDGRTQVLLAKIFSELERRGXXXXXXXXA
LELQARILKRVQMEKPDAVPAQKQFA

PF07719 // ENSGT00390000005979_0_Domain_11 (987, 1020)

ADICSEIAAHLVAQRDYEKAIKFYREALVYCETD
NKIILELARLYLTQNDLEACLRQCTLLLQSDQEN

PF07719 // ENSGT00390000005979_0_Domain_13 (1055, 1088)

EAAVMMMAELMFRKQDYEQAVFHLQQ
LLEHSPDNYVSLSRLIDLL-RRCGKLEEVPRLFXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSSTEKQES
VQLAVRTAEKQKE--ESQTAQGHTQLRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKDN
IPALLGMATAYMILKQTPRARNQLKRIAKMNWNPIDAEDF

PF00515 // ENSGT00390000005979_0_Domain_15 (1301, 1334)

EKSWLLLADIYIQSAKYDMA
EELLKRCLRHNRSCCKAYEYMGYIMEKEQAYSDAALNYEMAWKFGNQTNPAV--------
----------------------------------------------------

------------------------------------------------------------
-RRSRDLKPGLFTLINYYCQERYFH-HVLLVASEGIKRY-GSDPVFRFYHAYGTLMEGKT
QEALREFEAIKNKQDVSLCSLIALIYAHKMSPNP---DREAILESDARVKEQRKGAGEKA
LYHAGLFLWHVGRHDKAREYIDRMIKMSD-GSKQGHILKAWLDITRGKDAYTKKALKYFE
EGLQDGNDTFALLGKAQCLEMRQNYSGALETVNQIIVNFPSFLPAFVKKMKLQLALQDWD
QTVETAQRLLLQDSQNVEALRMQALYYVCREGDIEKA--------STKLENLGNALDAVE
PQNAQLFYNITLAFSRTCGRSQLILQKIQTLLERAFSLNPQQSQVATELGYQMILQGRVK
EALKWYKTAMTLDETSVPALVGLIQCQLIEGQLQDADQQLEFLNEIQQSIGKSAELIYLH
AVLAMKKNKRPEEVINILNDVLDTHFSQLEGLPLGIQYFEKLNPDFLLEIVTEYLSFCPM
QPASPGQPLCPLLRRCVSVLETVVRTVPGLLQTVFLIAKVKYLS---GDI-EAAFNNLQH
CLEHNPSYADAHLLLAQVYLSQEKIKLCSQSLELCLSYDFKVREYPLYHLIKAQSQKKMG
EIADAIKTLHMAMSLPGMKRIGASTKSKDRKTQVDTSHRLSI-FLELIEVHRLNGEQHEA
AKVLQDAIHEFSGTSEEVRVTIANADLALAQGDTERALSILRNVTAEQPYFIEAREKMAD
IYLKHRKDKMLYITCYREI---AERMPNP

PF13181 // ENSGT00390000005979_0_Domain_9 (810, 842)

RSFLLLGDAYMNILEPEEAIVAYEQALNQNP
KDGTLASKMGKALIKTHNYSMAISYYEAALKSGQKNYLCYDLAELLLKLKWYDKAEKVLQ
QALAHEP----------------VNELSALMEDGRCQVLLAKVYSKMERPGDAITALQQA
RELQARVLKRVQMEQPDAVPAQKRLAAEICAEIAKHSVV

PF14559 // ENSGT00390000005979_0_Domain_12 (1000, 1064)

QRDYEKAIKFYREALVHCETD
NKIMLELARLYLAQDDPDACLRQCAVLLQSDQDNEAATTMMADLMFRKQDYEQAVFHLQQ
LLERKPDNYMTLSRLIDLL-RRCGKLEDVPRFFSMAEKCNSRVKLEPGFQYCKGLYLWYT
GEPNDALRHFNKARKDSDWGQNALYNMIEICLNPDNETIGGEVFENLDGDLGNSTERQES
VQLAVRTAEKLLKELKPQTVQGQVQLRVMENYCLMATKQKSNVEQALNTFTEIAASEKDH
IPALLGMATAYMILKQTPRARNQLKRIAKMNWNAIDAEEFE

PF13181 // ENSGT00390000005979_0_Domain_15 (1302, 1329)

KSWLLLADIYIQSAKYDMA
EELLKRCLRHNRSCCKAYEYMGYIMEKEQAYTDAALNYEMAWKYSNQTNPAVGYKLAFN-
-YLKAKRY---------VDSIDVCHQ-VLEAHPTYPKIRKDILDKARASLRP

------------------------------------------------------------
-----MDSQELKTLINYYCQEKYFH-HVLLVASEGIKRY-GSDPVFRFYHAYGTLMEGKT
QEALREFETIKNKQDVSLCSLIALIYAHKMSPNP---DREAILESDARVKEQRKGAGEKA
LYHAGLFLWHIGRHDKAREYIDRMIKMSD-GSKQGHILKAWLDITRGKDPYTKKALKYFE
EGLQGGNDTFALLGKAQCLEMRQNYSGALETVNQIIVNFPSFLPAFVKKMKLQLALQDWD
QTVETAQRLLLQDSQNVEALRMQALYYVCREGDIEKA--------STKLENLANALNAME
PQNAQLFYNITLAFSRTCGRSQLILPKIQTLLERAFSLNPQQSEFATELGYQMILQGRVK
EALKWYKTAMTLDETSVPALVGFIQCQLIEGQLQDADQQLEFLNEIQQSIGKSAELIYLH
AILAMKKNKRQEEVINILNDVLDTHFSQLEDSPLGIQYFEKLNPDFLLEIVTEYLSICPM
QPASPGQPLCPLLRRCVSVLETVVRTVPGLLQTVFLIAKVKYLS---GDI-EAAFNNLQH
CLEHNPSYADAHLLLAQVYLSQEKIKLCSQSLELCLSYDFKVREYPLYHLIKAQSQKKMG
EIADAIKTLHMAMSLPGMKRTGASTKSKDRKTQVDTSHRLSI-FLELIEVHRLNGEQHEA
AKVLQDAIHEFSGTSEEVRVTIANADLVLAQGDTERALSILRNVTAEQPYFIEAREKMAD
IYLKHRKDKMLYITCYREI---AERMPNP

PF13181 // ENSGT00390000005979_0_Domain_9 (810, 842)

RSFLLLGDAYMNILEPEEAIVAYEQALNQNP
KDGTLASKMGKALIKTHNYSMAISYYEAALKSGQ-NYLYYDLAELLLKLKWYDKAEKVLQ
QALAHEP----------------VSELSALMEDGRCQVLLAKVYSKMERPGDAITALQQA
RELQARVLKRVQMEQPDAVPAQKHLAAEICAEIAKHS

PF14559 // ENSGT00390000005979_0_Domain_12 (998, 1064)

VAQRDYEKAIKFYREALVHCETD
NKIMLELARLYLAQDDPDACLRQCAVLLQSDQDNEAATTMMADLMFRKQDYEQAVFHLQQ
ILERKPDNYMTLSRLIDLL-RRCGKLEDVPRFFSMAEKCNSRVKLEPGFQYCKGLYLWYT
GEPNDALRHFNKARKDSDWGQNALYNMIEICLNPDNETIGGEVFENLNGDLGNSTERQES
VQLAVRTAEKLLKELKPQTIQGQVQLRVMENYCLMATKQKSNIEQALNTFTEIAASEKDH
IPALLGMATAYMILKQTPRARNQLKRVAKMNWNAIDAEEFE

PF13181 // ENSGT00390000005979_0_Domain_15 (1302, 1329)

KSWLLLADIYIQSAKYDMA
EELLKRCLRHNRSCCKAYEYMGYIMEKEQAYTDAALNYEMAWKYSNQTNPAVGYKLAFN-
-YLKAKRY---------MDSIDICHQ-VLEAHPTYPKIRKDILDKARASLRP

------------------------------------------------------------
-----MDSQELKTLINYYCQERYFH-HVLLVASEGMKRY-GSDPVFRFYHAYGTLMEGRT
QEALREFEAIKNKQDVSLCSLLALIYAHKMSPNP---DREAILESDARVKEQRKGAGEKA
LYHAGLFLWHIGRHDKAREYIDRMIKMSD-GSKQGHVLKAWLDITRGKEPYIKKALKYFE
EGLQDGNDTFALLGKAQCLEMRQNYSGALETVNQIIVNLPSFLPAFVKKMKLQLALQDWD
QTVETAQRLLLQDSQNVEALRMQALYYVCREGDIEKA--------STKLENLGNALDAME
PQNAQLFYDITLAFSRTCGRSQLILQKIQTLLERAFSLNPQQSEFATELGYQMILQGRVK
EALKWYKTAMTIDETSVSALVGFIQCQLMEGQLQDADQQLEFLNEIQLSIGKSAELIYLH
AVLAMKKNKRQEEVINLLNDVLDTHFSQLEGLPLGIQYFEKLNPDFLLEIVMEYLSFCPM
QPASPGQPLCPLLRRCVSVLETVVRTVPGLLQTVFLIAKVKYLS---GDI-EAAFNNLQH
CLEHNPSYADAHLLLAQVYLSQEKVKLCSQSLELCLSYDFKVRDYPLYHLIKAQSQKKMG
EIADAIKTLHMAMSLPGMKRIGASTKSKDRKTEVDTSHRLSI-FLELIDVHRLNGEQHEA
AKVLQDAIHEFSGTSEEVRVTIANADLALAQGDVERALSILQNVTAEQPYFIEAREKMAD
IYLKHRKDKMLYITCFREI---AERMAN

PF00515 // ENSGT00390000005979_0_Domain_9 (809, 842)

ARSFLLLGDAYMNILEPEEAIVAYEQALNQNP
KDGTLASKMGKALIKTHNYSMAITYYEAALKTGQKNYLCYDLAELLLKLKWYDKAEKVLQ
HALAHEP----------------VNELSALLEDGRCQVLLAKVYSKMERPGDAITALQQA
RELQARVLKRVQMEQPDAVPAQKHLAAEICAEIAKHSVAQRDYEKAIKFYREALVHCETD
NKIMLELARLYLAQDDPDSCLRQCALLLQSDQDNEAATMMMADLMFRKQDYEQAVFHLQQ
LLERKPN-----------------------------------------------------
-----------------------------------------------------STEKQES
VQLAVRTAEKLLKELKPQTVQGHVQLRIMENYCLMATKQKSDVEQALNTFTEIAASEKEH
IPALLGMATAYMILKQTPRARNQLKRIAKMNWNAIDAEEFEKSWLLLADIYIQSAKYDMA
EELLKRCLRHNRSCCKAYEYMGYIMEKEQAYTDAALNYEMAWKYSNRTNPAVGYKLAFN-
-YLKAKRY---------VDSIDICHQ-VLEAHPTYPKIRKDILDKARASLRP

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------AQCLEMRQDYSAAMYTVYRIIVSYASFLPALLKKVNLQLA-----
--------LLLQDHQNVEALRMLALYYLCREGDIEKX--------XXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXCGRSQLILQKVQTLLERAFSLAPQQSEFAAELGYQMILQGKVK
EAMKWYKIAMTLDETSVSALIGFIRCQLIEEQLQDVDHQLEFLSEIQQSIGKSAELIYLH
AVFAMKKNKPEDEVLHLLNDVLDTHFSHLADLPFGIQY--DLNPDFLE--ITEYL--FCM
QPASPGQPLSSLLRRCTSTLETIVRTVPGL

PF00515 // ENSGT00390000005979_0_Domain_4 (571, 608)

SQAIFLIAKVKYLS---GDI-EAAYNNLQH
CLEHNPSYADANLLMAQVYLSQGKFKLCSQSLELCLSYNFKVRESPLYHLIKAQSQKKMG
EIAEAIKTLHMAMSLPGMKRIGTSSKSKYRKTEVDTNHRLSI-FLELVEVHRLNGEQHEA
AKVLQDAIHEFSGTSEE

PF07721 // ENSGT00390000005979_0_Domain_8 (738, 763)

LRVTIANADLALAQGDTERALNMLRNVTVEQPYYIEAKEKMAD
IYLKHRKEKMLYITCYXXX---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXAINYYEAALKGGQQ

PF00515 // ENSGT00390000005979_0_Domain_9 (876, 925)

NYLCYDLAELLIKLKWYDKAEKVLQ
HALAHEP----------------V

ENSGT00390000005979_0_Linker_9_10 (925, 934)

NELSALMED

PF00515 // ENSGT00390000005979_0_Domain_10 (934, 967)

GRSQVLLAKVYSKMDRPGDAVTSLQQA
RELQSR

ENSGT00390000005979_0_Linker_10_11 (967, 987)

VLKRVQMEQPDAVPAQKHLA

PF00515 // ENSGT00390000005979_0_Domain_11 (987, 1020)

AEICAEIAKHSVAQRDYEKAIKFYREALVHCETD
NKTMLELARLYLAQDDPDACLRHCALLLQSDQDN

PF00515 // ENSGT00390000005979_0_Domain_13 (1055, 1088)

EPATMMMADLMFRKQDYEQAVFHLQQ
LLERKPDNYMTLSRLIDLL-RRCGKLEDVPRFFLMAEKRNSRAKFEPGFQYCKGLYLWYT
GEPNDALRNFNKARKDSDWGQNALYNMIEICLNPDNETIGGEVFENLDGDLGNSNEKQES
LQLAVRTAEKLLKELKPQTVQGHVQLRIMENYCLMATKQKSNVEQALNTFTEIATSEKDH
IPALLGMATAYMILKQTPRARNQLKRIAKMNWNPIDAEEFEKSWLLLADIYIQSAKYDMG
EXXXXXXXXXXXSCCKAYEYTGYIMEKEQSYTDAAVNYEMAWKHGSQTNPAVGCKLAFN-
-YLKAKRY---------VXXXXXXXX-VLETHPTYPKIRKDILDKARTSLRP

------------------------------------------------------------
--------------------MRSVHSKCLLCA----------KNNFPPYNLDNLDFSGKI
QEALREFEAIKNKQDISLCSLIAVIYAHKMSPNP---DREAILESDARVKEQRKGADQ

PF13181 // ENSGT00390000005979_0_Domain_0 (179, 208)

KA
LYHAGLFLWHLGRHDKAREYIERVIKMPN-NSNEGQILKAWLDITRGKEPYAKKALRCFE
EGLQDGKDIFALLGKAQCLEMRQNYSGALEAVNQIIVNFPSFLPAFIKKMKLQLALQDWD
QMVETAQRLLFQDNQNVEALRMLALYCLCREGNVEKA--------TTKLENLGNALDVME
PQNAQLFYKITIAFSRTCGRNQLILQKLQTLLEKAFRLTPQQSEFAAEIGYQMILQGKVK
EALTWYQTAMTLDNTSISALVGFIRCQLMDGQLQEADQQLEFLSEVQQSMEKSTELIYLH
ATLAMKKNKQEEEVIHLLNDVLDTHFSHLEDLPLGIQYFETLNPDFLLEIITEYLNFCPM
LPASPGQPLTPFLRRCMLVLETIVRTVPGLLQAVFLIAKVKYLS---GNI-EAAYSNLQH
CLDHDPSYADAHLLMAQVYLSQEKFKLCSQSLELCLSYNFNVREYPLYHLIKAQSQKKLG
EITEAIKTLHMAMNLPGVRRTGASSKSKYRKTEVDTSHRLSI-FLELVEVHRLNGEQHEA
AKVLQDAIHEFAGTSEEL

PF07721 // ENSGT00390000005979_0_Domain_8 (739, 762)

RVTIANANLALAQGDVERALSIL

ENSGT00390000005979_0_Linker_8_9 (762, 810)

RNVTAEQAYFIEAKEKMAD
IYLKHRKEKMLYITCYREI---AERIPSP

PF13181 // ENSGT00390000005979_0_Domain_9 (810, 842)

RSFLLLGDAYMNIQEPEEAIVAYEQALNQNP
KDGMLASKIGKALVKTHNYSKAITYYEAALKSGQQNYLCYDLAELLLKLKLDEKAEKVLQ
HALAHEP----------------VNELSALMEDGRSQVLLAKVYSKIGRPGEAVTSLQQA
RELQARVLKRVQMEQPDAVPAQKHLAAEICAEIAKHSVAQQDYEKAIMFYREALVHCETD
NKIM

PF07721 // ENSGT00390000005979_0_Domain_12 (1025, 1043)

LELARLYLAQGDPDACLRHCVMLLQNDQDNESATMMMADIMFRKQDYEQAVFHLQQ
LLERKPDNYMTLSRLIDLL-RRCGKFDDIPRFFVMAEKHNSRAKLEPGFQYCKGLYLWYT
GEPNDALRHFNKARKDSEWGQNALYNMIEICLNPDNETIGGEVFENLDGDLGNSTEKQES
VQLAVRTAEKLLKELKPQTLQGHVQVRIMENYCLMATKQKPNVEQALNTFTEVAKSENDH
IPALLGMATAYMILKQIPKARNQLKRITKMNWNAIDAEDFE

PF13181 // ENSGT00390000005979_0_Domain_15 (1302, 1329)

KSWLLLADIYIQSAKYDMA
EDLLRQCLRHNRSCCKAYEYMGYIMEKEQAYSDAASNYERAWKYGNQTNPAVGYRLAFN-
-YLKAKRY---------VDAIDICHQ-VLETHPAYPKIRKDILDKARASLRP

------------------------------------------------------------
-----MDSQGLKILINYYCQERYFH-HVIIVASEGIKRY-GSDPIFRFYYAYGTLME---
-------------------------------------DREAILESDARVKEQRKVAGQKA
LYHAGLFLWHIGRHDKAREYIDRMIKMSN-GSKEGQILRAWLDITRGKEPYTKKALRYFE
EGLQDGNDIFALLGKAHCLEIRQNYSGALETVNQIIVNFPSFLPAFVKKMKLQLALQDWD
QTVETAQRLMLQDNQNVEALRILALYYLCREGNIEKA--------STKLENLGNTLDAME
PQNAQLFYKITVAFSRTCGRNQVILQKIQMLLERAYSLTPHHSEFATELGYQMILQGKVK
EALKWYKTAMTLDETSVSALIGFIRCQLIEGQLQDADQQLEFLSEIQQSIGKSAELIYLH
AVLAMKKNKRKEEVIHLLNDVLDTHFSQLEDLPLGIEYFEKLNPDFLLEIITEYLNFCPM
QPSSLGQPLSPLLRRCTSVLETIVRTVPGLLQAVFLIAKVKYLS---GDI-EAAYNNLQH
CLEHNPSYADAHLLMAQVYLSQEKFKLCSQSLELCLSYNFKVREYPLYHLIKAQSQKKMG
EIAEAIKTLHMAMSLPGMRRSGATSKSKYRKAEVDASHRLSI-FLELVEVHCLNGEQHEA
AKVLQDAIHEFSGTSEELRVTIANADLALAQGDVERALNMLRNVTTEQPYFIEAKEKMAD
IYLKYRKEKMLYITCYREI---AERMPNPR

PF00515 // ENSGT00390000005979_0_Domain_9 (811, 842)

SFLLLGDAYMNIQEPEEAIVAYEQALNQNP
KDGTLASKIGKALVKTHNYSKAITYYEAALKSGQQNCLCYDLAELLLKLKWYDKAEKVLQ
HALAHEP----------------VNELSALMEDGRSQVLLAKVYSKMERPGDAVTSLQKA
RELQARVLKRVQMEQPDAVPAQKHLAAEICAEIAKHSVTQRDYEKAIMFYKEALVHCETD
NKVSTFIKF---------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------

------------------------------------------------------------
-----MDSQELKTLINYYCQERYFH-HVLLVASEGIKRY-GSDPVFRFYHAYGTLMEGKT
QEALREFEAIKNKQDVSLCSLLALIYAHKMSPNP---DREAILESDARVKEQRKGAGEKA
LYHAGLFLWHIGRHDKAREYIDRMIKMSD-GSKQGHVLKAWLDITRGKEPYTKKALKYFE
EGLQDGNDTFALLGKAQCLEMRQNYSGALETVNQIIVKFPSFLPAFVKKMKLQLALQDWD
QTVETAQRLLLQDSQNVEALRMQALYYVCREGDIEKA--------STKLENLGNALDAME
PQNAQLFYNITLAFSRTCGRSQLLLQKIQMLLERAFSLNPQQSEFATELGYQMILQGRVK
EALKWYKTAMTLDETSVSALVGFIQCQLIEGQLQDADQQLEFLNEIQQSIGKSAELIYLH
AVLAMKKNKRQEEVINLLNDVLDTHFSQLEGLPLGIQYFEKLNPDFLLEIVMEYLSFCPM
QPASPGQPLCPLLRRCVSVLEAVVRTVPGLLQTIFLIAKVKYLS---GDI-EAAFNNLQH
CLEHNPSYADAHLLLAQVYLSQEKVKLCSQSLELCLSYDFKVRDYPLYHLIKAQSQKKMG
EIADAIKTLHMAMSLPGMKRIGASTKSKDRKTEVDTSHRLSI-FLELIDLHRLNGEQHEA
AKVLQDAIHEFSGTSEEVRVTIANADLALAQGDIERALSILQNVTAEQPYFIEAREKMAD
IYLKHRKDKMLYITCFREI---AERMANP

PF13181 // ENSGT00390000005979_0_Domain_9 (810, 842)

RSFLLLGDAYMNILEPEEAIVAYEQALNQNP
KDGTLASKMGKALIKTHNYSMAITYYEAALKTGQKNYLYYDLAELLLKLKWYDKAEKVLQ
HALAHEP----------------VNELSALMEDGRCQVLLAKVYSKMERPGDAITALQQA
RELQARVLKRVQMEQPDAVPAQKHLAAEICAEIAKHS

PF14559 // ENSGT00390000005979_0_Domain_12 (998, 1064)

VAQRDYEKAIKFYREALVHCETD
NKIMLELARLYLAQDDPDSCLRQCALLLQSDQDNEAATMMMADLMFRKQDYEQAVFHLQQ
LLERKPDNYMTLSRLIDLL-RRCGKLEDVPRFFSMAEKRNSRAKLEPGFQYCKGLYLCLR
PEK---------------------------------TTSGFNRSNLFFIIYSNSTEKQES
VQLAVRTAEKLLKELKPQTVQGHVQLRIMENYCLMATKQKSNIEQALNTFTEIAASEKEH
IPALLGMATAYMILKQTPRARNQLKRIAKMNWNAIDAEEFE

PF13181 // ENSGT00390000005979_0_Domain_15 (1302, 1329)

KSWLLLADIYIQSAKYDMA
EELLKRCLRHNRSCCKAYEYMGYIMEKEQAYTDAALNYEMAWKYSNRTNPAVGYKLAFN-
-YLKAKRY---------VDSIDICHQ-VLEAHPTYPKIRKDILDKARASLRP

------------------------------------------------------------
-----MDSQGLKTLINYYCQEKYFH-HVLLIASEGVKRY-GNDPVFRFYHAYGTLMEGKT
QEALREFEAIKNKQDVSLCSLIALIYAHKMSPNP---DREAILESDARVKEQRKGAGPKA
LYHAGLFLWHIGRHDKAREYIDRMIKMSN-GSKEGQVLKAWLDITRGKEPYTKKALRYFE
EGLQDGNDIFALLGKAQCLEMRQNYSGALDTVNQIIVNFPSFLPAFVKKMKLQLALQDWD
QTVETAQRLMLQDSQNVEALRILALYYLCREGDIEKA--------ATKLENLENALDAME
PQNAQLFYKITVAFSRTCGRSQLILQRIQTLLEKAFSLTPQQSEFATELGYQMILQGNVK
EALKWYKTAMTLDETSVPALIGFIRCQLIEGQLQDADQQLEFLREIQQSIGKSAELIYLH
AILAMKKNKRQEEVINLLNDVLDTHFSQLEDLPLGIKYFENLNPDFLLEIITDYLNFCPM
QPASPGQPLSPLLRRCTSILETIVRTVPGLLQAVFLIAKVKYLS---GDI-EAAYNNLQH
CLEHSPSYADAHLLMAQVYLSQEKFKLCSQSLELCLSYNFKVREYPLYHLIKAQSQKKMG
EIAEAIKTLHMAMSLPGMRRIGASSKSKYKKTEVDANHRLSI-FLELVEVHRLNGEQHEA
AKVLQDAIHEFSGTSEELRVTIANADLALAQGDVERALSMLRNVTAEQPYFIEVKEKMAD
IYLKHRKEKMLYITCYREI---AERMPSPR

PF00515 // ENSGT00390000005979_0_Domain_9 (811, 842)

SFLLLGDAYMNIQEPEEAIVAYEQALNQNP
KDGTLASKIGKALVKTHNYSKAITYYEAALKSGQQNYLCYDLAELLLKLKWYDKAEKVLQ
HALAHEP----------------VNELSALMEDGRSHVLLAKVYSKMERPGDAITSLQQA
RELQARVLKRVQMEQPDAAPAQKHLAAEICAGIAKHSVAQRDYEKAIKFYREALVHCETD
NKIMLELARLYLIQDDPEACLRHCALLLQSDQDNEAATMMMADLMFRKQDYEQAVFHLQQ
LLERKPDNYMTLSRLIDFL-RRCGKLEDVPRFFLMAEKRNSRAKLEPGFQYCKGLYLWYT
GEPNDALRHFNKARKDSDWGQNALYNMIEICLNPDNETVGGEVFENLDADLGNSTEKQES
VQLAVRTAEKLLKELKPQTIQGHVQLRIMENYCLVATKQKSNVEQALNTFTEIATSEKDH
IPALLGMATAYMILKQTPRARNQLKRIAKMNWNPIDAEDFEKSWLLLADIYIQSAKYDMA
EELLKQCLRHNRSCCKAYEYMGYIMEKEQAYTDAALNYEMAWKHGNQTNPAVGYKLAFN-
-YLKAKRY---------VDAIDVCHQ-VLEAHPTYPKIRKDILDKARTSLRP

------------------------------------------------------------
-----MDSQGLKTLINYYCQERYYH-HVLLVASEGMKKY-SSDPVFRFYHAYGTLMEGKA
QEALREFEAIKNKQDVSLCSLMALMYVHKMSPNP---DREAILELDTKMKEQRKEAGRKA
LYHAGLFLWHIGRHDKAREYIDRMSKMPH-DSNEGPILKAWLDITRGKEPYAKKALRYFE
EGLQDGNDIFALLGKVLCLEIRQNYSGALETVSQIIVNFPSFLPAFEKKMKLQLALQDWD
QTVETAQRLLLQDNHNVEALRMLALYYLCREGDVEKA--------ATKLENLGNALDVME
PQNAQLFYKITLAFSRTCGRNQLILQKVQSFLEKAFSLTPQQAEIATELGYQMILQGKVK
EAWKWYRTAMTLNESNISAVTGLIRCQLIEGQLQDADQQLEFFSEFQQSMGKSAELMYLH
AVLATKKNNRQDEVINLLNDVVNTHFSHLEDLPLGIQYFEKLNPDFLLEVVTEYLNLCPI
QPAGPGQPLSPVLRRCSSVLETIIRSVPGLPQAVFLMAKVKYLS---GDT-EAAYNNLQH
CLEHSPSYAEAHLLMAQVYLSQDKVKLCSQSLELCLSYNFNVREYPLYHLIKAQSQKKMG
EVAEAIKTLHMAMNLPGMRRSRASSKSK-HRTEVDASHRLSI-FLELVEVHRLNGEQHEA
AKVLQDAIHEFSGTCEELRVTIANADLALAQGDTDRALSMLRNVTTEQPYFIEAKEKMAD
IYLKHRKEKMLYITCYREI---AERMPSP

PF13181 // ENSGT00390000005979_0_Domain_9 (810, 842)

RSFLLLGDAYMNIQEPEEAIVAYEQALNQNP
KDGTLARKIGKALVKTHNYSKAITYYEAALKSGQQNCLCYDLAELLLRLKLYEKAEKVLQ
HSLAHEP----------------VSELSALMVDGRSQVLLAKVYSKMERPSDAIAALQQA
RELQARILKRVQMEQPDAVPSQKHFAAEICAEIAKHSAAQRDYEKAITFYREALVHCETD
SKIMLELAQLYLAQEDLDASLRHCALLLQRDQDNEPAT

PF13174 // ENSGT00390000005979_0_Domain_13 (1059, 1087)

MLMADLMFRKQDYEQAVYHLQQ
LLDRKPDNFMTLSRLIDLL-RRCGKLEDVPRFFLMAEKHNSRTKLEPGFQYCKGLHFWYT
GEPNDALRHFNKARKDSDWGQNALYNMIEICLNPDNETIGGEVFENLNGDLGTSPEKQES
VQLAVRTAEKLLKELKPQTVQGRLQLRIMENCCLMATKQKSSVEQALNTFTEIAASEKDH
IPALLGMATAYMILKQTPKARNQLKRIAKMPWNPIEAEDLE

PF13181 // ENSGT00390000005979_0_Domain_15 (1302, 1328)

KSWLLLADIYIQSAKYDMA
EELLKRCLCHNRSCCKAYEYMGYIMEKEQAYTDAAFNYEMAWKHSNQTNPAVGYKLAFN-
-YLKAKRY---------VDAIDVCHQ-VLEAHPTYPKIRKDILDKARASLRP

------------------------------------------------------------
------------TLINYYCQERYFH-HVITVASEGIKRY-GSDPVFRFYHAYGTLMEGKI
QEALREFEAIKNKQDVSLCSLIALIYAHKMSPNP---DREAILESDARMKEQRKGAGQQA
LYHAGLFLWHIGRNDKAREYIDRMIKMSN-GSKEGQILRAWLDITRGKEPYTKKALRYFE
EGLQDGNDIFALMGKAQCLEIRQNYSGALETMNQIIVNFPSFLPAFVKKMKLQLALQDWD
QTVETAQRLMLQDNQNVEALRMLALYYLCREGEIEKA--------STKLEDLGNTLDAME
PQNAQLFYKVTIAFSRTCGRNQLILQKIQMLLERAFSLTPHHSEFASELGYQMILQGKVK
E-LKWYNTAMTLDETSVSALIGFIRCQLIEGQLQDADQQLEFLSEIQQSIGKSAELIYLH
AVLAMKKNKRQEEVVHLLNDVLDTHISQLEDLPLGIEYFEKLNPDFLLEIITEYLNFCPM
QPASLGQPLSPLLRRCTSILETIVRTVPGLLQAVFLIAKVKYLS---GDI-EAAYNNLQH
CLEHSPSY

PF00515 // ENSGT00390000005979_0_Domain_6 (609, 642)

ADAHLLMAQVYLSQEKFKLCSQSLELCLSYNFKVRDYPLYHLIKAQSQKKMG
EIAEAIKTLHMAMSLPGMRRTGSSSKSKYRKPEVDAGHRLSI-FLELVEVHCLNGEQHEA
AKVLQDAIHEFAGTSEE

PF07721 // ENSGT00390000005979_0_Domain_8 (738, 763)

LRVTIANADLALAQGDVERALSMLRNVTA-QPYFIEAKEKMAD
IYLKYRKEKMYNY-CXXXX---XXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXAITYYEAALKSGQQ

PF07719 // ENSGT00390000005979_0_Domain_9 (876, 909)

NYLCYDLAELLLKLKWYDKAEKVLQ
HALAHEPXX--------------XXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXA
RELQARVLKRVQIEQPDAVPAQKHLA

PF00515 // ENSGT00390000005979_0_Domain_11 (987, 1020)

AEICAEIAKHSVAQRDYEKAIKFYKEALVHCETD
NKIMLELARLYLAQGDPDACLQHCALLLQTDQDN

PF00515 // ENSGT00390000005979_0_Domain_13 (1055, 1088)

EAAAMMMADLMFRKQDYEQAVFHLQQ
LLERKPD

ENSGT00390000005979_0_Linker_13_14 (1088, 1127)

NYMTLSRLIDLL-RRCGKLEDVPRFFLMAEKRNSRAKFE

PF00515 // ENSGT00390000005979_0_Domain_14 (1127, 1153)

PGFLYCRGLYLWYT
GDPNDALRHFNK

ENSGT00390000005979_0_Linker_14_15 (1153, 1301)

ARKDSDWGQNALYNMIEILT----------------------------
-----------------------PNLRIMENYCLMATKQKSSVEQALNTFTEVATSEKDH
IPALLGMATAYMILKQTPRARNQLKRIAKMNWNPIDAEEF

PF00515 // ENSGT00390000005979_0_Domain_15 (1301, 1334)

EKSWLLLADIYIQSAKYDMA
EELLKRCLRHNRSCCKAYEYMGYIMEKEQAYTDAALNYEMAWKYSNQTNPAVGYKLXXXX
XXXXXX-----------XXXXXXXXX-VLEVHPTYPKIRKDILDKARTSLRP

------------------------------------------------------------
-----MDSQGLKTLINYYCQERYYH-HVLLVASEGMKKY-SSDPVFRFYHAYGTLMEGKS
QEALREFEAIKNKQDVSLCSLIALMYVHKMSPNP---DREAILELDTKMKEQRKEAGRKA
LYHAGLFLWHIGRHDKAREYIDRMSKMPH-DSNEGPILKAWLDITRGKEPYAKKALRYFE
EGLQDGNDIFALLGKVLCLEMRQNYSGALETVSQIIVNFPSFLPAFEKKMKLQLALQDWD
QTVETAQRLLLQDTHNVEALRMLALYYLCREGDVEKA--------AAKLENLGNALDVME
PQNAQLFYKITIAFSRTCGRNQLILQKVQGFLEKAFSLTPQQAEIATELGYQMILQGKVK
EAWKWYRTAMTLNESNISAVTGLIRCQLIEGQLQDADQQLEFFSEFQQSMGKSAELMYLH
AVLATKKNNGQEEVVNLLNDVVNTHFSHLEDLPLGIQYFEKLNPDFLLEVVTEYLNFCPI
QPAGPGQPLSPVLRHCSSVLETIIRSVPGLPQAVFLMAKVKYLS---GDI-EAAFNNLQH
CLEHSPSYAEAHLLMAQVYLSQEKVKLCSQSLELCLSYNFNVRDYPLYHLIKAQSQKKMG
EIAEAIKTLHMAMNLPGMKRSRASSKSK-HRTEVDASHRLSI-FLELVEVHRLNGEQHEA
AKVLQDAIHEFSGTCEELRVTIANADLALAQGDTERALSMLRNVTTEQPYFIEAKEKMAD
IYLKHRKEKMLYITCYREI---AERMPSP

PF07719 // ENSGT00390000005979_0_Domain_9 (810, 842)

RAFLLLGDAYMNIQEPEEAIVAYEQALNQNP
KDGTLARKIGKALIKTHNYTKAITYYEAALKSGQQNCLCYDLAELLLRLKLYEKAEKILQ
HSLAHEP----------------VNELSALMEDGRSQVLLAKVYSKMERPSDAIASLQQA
RELQARILKRVQMEQPDAVPSQKHFAAEICAEIAKHSAAQRDYEKAITFYREALVHCETD
SKIMLELAQLYLAQEDLDASLRHCALLLQRDQDNEPATMLMADLMFRKQDYEQAVFHLQQ
LLERKPDNFMTLSRLIDLL-RRCGKLEDVPRFFSMAEKHNSRTKLEPGYQYCKGLHFWYT
GEPNDALRHFNKARKDSDWGQNALYNMIEICLNPDNETIGGEVFENLDGDLGSSTEKQES
VQLAVRTAEKLLKELKPQTVQGRLQLRVMENCCLMATKQKSSVEQALSTFTEIAASEKDH
IPALLGMATAYMILKQTPKARNQLKRIAKMSWNPIEAEDLE

PF13181 // ENSGT00390000005979_0_Domain_15 (1302, 1328)

KSWLLLADIYIQSAKYDMA
EELLKRCLCHNRSCCKAYEYMGYIMEKEQAYTDAAFNYEMAWKHSNQTNPAVGYKLAFN-
-YLKAKRY---------VDAIDICHQ-VLEAHPAYPKIRKDILDKARASLRP

------------------------------------------------------------
---VHCVLHSLLTLINYYCQEKYFH-HVLLTASEGVKRY-GNDPVFRFYHAYGTLMEGKT
QEALREFEAIKNKQDVSLCSLIALIYAHKMSPNPALLDREAILESDARVKEQRKGAG

PF00515 // ENSGT00390000005979_0_Domain_0 (178, 212)

PKA
LYHAGLFLWHVGRHDKAREYIDRMIKVSN-G

ENSGT00390000005979_0_Linker_0_1 (212, 249)

SKEGQVLKAWLDITRGKESYTKKALRYFE
EGLQDGND

PF00515 // ENSGT00390000005979_0_Domain_1 (249, 282)

IFALLGKAQCLEMRQNYSGALETVNQIIVNFPSFLPAFVKKMKLQLALQDWD
QTVETAQRLILQDNQNVEALRILALYYLCREGDIEKA--------ATKLESLENALDAME
PQNAQLFYKITVAFSRTCGRSQLILQKIQTLLERAFSLTPQQ

PF00515 // ENSGT00390000005979_0_Domain_3 (403, 436)

SEIATELGYQMILQGKVK
EALKWYKTAMTLDETSVPALIGFIRCQLIEGQLQDAEQQLEFLREIQQSIGKSAELTYLH
AILAMKKNK-QEEVINLLNDVLDTHLSQLEDLPLGIQYFENLNPDFLLEIITEYLNFCPM
QPASLGQPLSPLLRRCTSILETIVRTVPGLLQAVFLIAKVKYLS---GDI-EATYNNLQH
CLEHNPSY

PF00515 // ENSGT00390000005979_0_Domain_6 (609, 642)

ADAHLLIAQVYLSQEKFKLCSQSLELCLSYNFKVREYPLYHLIKAQSQKKMG
EIAEAIKTLHMAMSLPGMRRIGASAKSKYRKTEVDANHRLSI-FLELVEVHRLNGEQHEA
AKVLQDAIHEFSGTSEE

PF07721 // ENSGT00390000005979_0_Domain_8 (738, 763)

LRVTIANADLALAQGDVERALSMLR

ENSGT00390000005979_0_Linker_8_9 (763, 809)

NVTAEQPYFIEAKEKMAD
IYLKCRKEKMLYITCYREI---AERMPS

PF00515 // ENSGT00390000005979_0_Domain_9 (809, 842)

PRSFLLLGDAYMNIQEPEEAIVAYEQALNQNP
KDGTLACKIGKALVKTHNYLKAITYYEAALKSGQQNYLCYDLAELLLKLKWYDKAEKVLQ
HALAHEPGI--------------VNELSALMED

PF00515 // ENSGT00390000005979_0_Domain_10 (934, 967)

GRSHVLLAKVYSKMERPGDAITSLQQA
RELQAR

ENSGT00390000005979_0_Linker_10_11 (967, 987)

VLKRVQMEQPDAAPAQKHLA

PF07719 // ENSGT00390000005979_0_Domain_11 (987, 1020)

AEICAGIAKHSVAQRDYEKAIKFYREALVHCETD
NKIMLELARLYLAQDEPDACLRHCAMLLQSDQDN

PF07719 // ENSGT00390000005979_0_Domain_13 (1055, 1088)

EAATMMMADLMFRKQDYEQAVFHLQQ
LLERKPDNYMTLSRLIDFL-RRCGKLEDVPRFFLMAEKRNSRAKLEPGFQYCKGLYLWYT
GEPNDALRHFNKARKDSDWGQNALYNMIEICLNPDNETVGGEVFENLDGDLGNSSEKQES
VQLAVRTAEKLLKELKPQTIQGHVQLRIMENYCLVATKQKSNVEQALNTFTEIATSEKDH
IPALLGMATAYMILKQTPRARNQLKRIAKMNWNPIDAEDF

PF00515 // ENSGT00390000005979_0_Domain_15 (1301, 1334)

EKSWLLLADIYIQSAKYDMA
EELLKRCLRHNRS

ENSGT00390000005979_0_Linker_15_16 (1334, 1370)

CCKAYEYMGYIMEKEQAYTDAALNYEMAWKHGSQTN

PF00515 // ENSGT00390000005979_0_Domain_16 (1370, 1415)

PAVGYKLAFN-
-YLKAKRY---------VDAIDVCHQ-VLEAHPAYPKIRKDILDKARTSLRP

------------------------------------------------------------
-----LETLSLKTLMHYYCQERYYH-HVQTVANEGLKRH-GSDPIFMFYHAFGVLMEGRI
QEAIRELEDIKNKQDISLCSLIALLYAHKRSADP---DRDAILDLDIKMKEIRKTAGQK

PF07721 // ENSGT00390000005979_0_Domain_0 (180, 199)

A
LYYAGLLLWHLGRHDKAREYVDRMIKISN-GCREGLVLRAWLDLTCGKEAYAKKSLKYFE
EGMQDLSDIFAQLGKAQYFEMRQNYSGALETVNQIIVNFPNFLPAFEKKMKLQLALQDWE
QTIETAHRIIQKNNQNVEALRMLALHHLCREGNIQEA--------TGKLGDLLGALNAVE
PRNAQLYYKIAVAFSRTCGRNQVILQQTQTLIERAFDLAPQNSEIATELGYQMILQGKVK
EALKWYETAMTLDETSVSALIGIIRCQLLEGQLQDADQQLEFLNEIQPSIGKCEVLSYLH
AVLAMKKHKRQEEVISLLNDVLDTHFSNLQGVPLSVQYFEKLNPDFLLEIIREYLHFCPT
QPASAGQPPSPLLSHCASVLEAVVKMVPGLLQAVFLMAKVKYFS---GDA-AAASSNLKH
CLEHNPSYAEAHLLMAQVYLSENNFKLCSQSLELCLSYNFEIREHPLYHLIKAQSQKKMG
EISEAIKTLHIAMSLPGMRRIAMSSKSKYRSPEIDANSRLSI-FLELVDVHRLNGEQHEA
AKVLQDAINEFSGTPEEL

PF07721 // ENSGT00390000005979_0_Domain_8 (739, 762)

RVTIANADLALAQGDIEQALTML

ENSGT00390000005979_0_Linker_8_9 (762, 814)

RNVSPDQPYFVEAKEKMAH
IYLQHRKEKKLYASCYRDL---VDKLPNSHTFL

PF00515 // ENSGT00390000005979_0_Domain_9 (814, 842)

LLGDAYMNIQEPEEAIEVYEQALKRNP
KDGTLASKIGKALVKTHNYSKAICYYEAALKNGKQSVLCHDLAELLLKLRQYEKAEKVLQ
HALDHEP----------------VNDLSALMEDGRYQVLLAKIYSRMEKPDEAISSLQQA
RDLQARILKRVQMEQPDAVPTQKQLASEICAELAKHSAAQRDFEKAIKFYKEALVYWDTD
NKVMLELARLYLAQDDPDGCQRQCALLLKNDRDNEAATMMMADLMFRKQDYEQAVFHFQQ
LLERQPDNYTILSRLIDLL-RRAGKLEEVPRFLVMAEKHSSRAKLEPGFHYCKGLYLWYT
GEPNDALRHFNKARKDSDWGQNAIYNMIEICLNPDNETIGGEVFENLDGDLGNSSEKQES
VQLAVRTAEKLLKELKPQTIQGHVQLRIMENYCLMATKQKSNVERALNTFTEIATSEKDH
VPALLGMATAFMILKQTPRARNQLKRISKMNWNPIDAEEFEKSWLLLADIYIQSAKYDMA
GELLKRCLRHNRVSDNFSVYSRSILSVEVLLVASALMYFIGWIFQNST------------
----------------------------------------------------

------------------------------------------------------------
-----MDSQGLKTLINYYCQERYYH-HVLLVASEGMKKY-SSDPVFRFYHAYGTLMEGKS
QEALREFEAIKNKQDVSLCSLIALMYVHKMSPNP---DREAILELDTKMKEQRKEAGRKA
LYHAGLFLWHIGRHDKAREYIDRMSKMPH-DSNEGPILKAWLDITRGKEPYAKKALRYFE
EGLQDGNDIFALLGKVLCLEMRQNYSGALETVSQIIVNFPSFLPAFEKKMKLQLALQDWD
QTVETAQRLLLQDTHNVEALRMLALYYLCREGDVEKA--------AAKLENLGNALDVME
PQNAQLFYKITIAFSRTCGRNQLILQKVQGFLEKAFSLTPQQAEIATELGYQMILQGKVK
EAWKWYRTAMTLNESNISAVTGLIRCQLIEGQLQDADQQLEFFSEFQQSMGKSAELMYLH
AVLATKKNNGQEEVVNLLNDVVNTHFSHLEDLPLGIQYFEKLNPDFLLEVVTEYLNFCPI
QPAGPGQPLSPVLRHCSSVLETIIRSVPGLPQAVFLMAKVKYLS---GDI-EAAFNNLQH
CLEHSPSYAEAHLLMAQVYLSQEKVKLCSQSLELCLSYNFNVRDYPLYHLIKAQSQKKMG
EIAEAIKTLHMAMNLPGMKRSRASSKSK-HRTEVDASHRLSI-FLELVEVHRLNGEQHEA
AKVLQDAIHEFSGTCEELRVTIANADLALAQGDTERALSMLRNVTTEQPYFIEAKEKMAD
IYLKHRKEKMLYITCYREI---AERMPSP

PF07719 // ENSGT00390000005979_0_Domain_9 (810, 842)

RAFLLLGDAYMNIQEPEEAIVAYEQALNQNP
KDGTLARKIGKALIKTHNYTKAITYYEAALKSGQQNCLCYDLAELLLRLKLYEKAEKILQ
HSLAHEP----------------VNELSALMEDGRSQVLLAKVYSKMERPSDAIASLQQA
RELQARILKRVQMEQPDAVPSQKHFAAEICAEIAKHSAAQRDYEKAITFYREALVHCETD
SKIMLELAQLYLAQEDLDASLRHCALLLQRDQDNEPATMLMADLMFRKQDYEQAVFHLQQ
LLERKPDNFMTLSRLIDLL-RRCGKLEDVPRFFSMAEKHNSRTKLEPGYQYCKGLHFWYT
GEPNDALRHFNKARKDSDWGQNALYNMIEICLNPDNETIGGEVFENLDGDLGSSTEKQES
VQLAVRTAEKLLKELKPQTVQGRLQLRVMENCCLMATKQKSSVEQALSTFTEIAASEKDH
IPALLGMATAYMILKQTPKARNQLKRIAKMSWNPIEAEDLE

PF13181 // ENSGT00390000005979_0_Domain_15 (1302, 1328)

KSWLLLADIYIQSAKYDMA
EELLKRCLCHNRSCCKAYEYMGYIMEKEQAYTDAAFNYEMAWKHSNQTNPAVGYKLAFN-
-YLKAKRY---------VDAIDICHQ-VLEAHPAYPKIRKDILDKARASLRP

------------------------------------------------------------
-----MDSQELKTLINYYCQERYFH-HVLLVASEGMKKY-GSDPVFRFYYAYGTLMEGKA
QEALREFEAIKNKQDVSLCSLIALMYIHKMSPDP---DREAILELDTKMKEQRKEAGWKA
LYHAGLFLWHIGRHDKAREYIDRMSKMPH-DSNEGPILKAWLDITRGKEPYAKKALRCFE
EGLQDGNDIFALLGKVLCLEMRQNFSGALETVSQIIVNFPSFLPAFEKKMNLQLALQDWD
QTVETAQRLLVQDSNNVEALRMLALYYLCREGDIEQA--------AANLENLGNALDVME
PQNAQLFYKITMAFSRTCGRNQLILEKVQNFLEKAFSLTPQQPEIATELGYQMIFQGKVK
EAWKWYKTAMTLNETSISAVTGLIRCQLIEGQLQDADQHLEFFSEFQQSMGKSAELMYLR
AVLAAKKNNRQEEIINLLNDVVETHFSHLEDLPLGVQYFEKLNPDFLLEVITEYLNFCPV
QPASPGQPLSVVLRHCTSILETIIRTVPGLLQAVFLMAKIKYLS---GDN-EAAYSNLQH
CLEHSPSYSDAHLLMAQVYLSQEKVKLCSQSLELCLSYNFNVRQYPLYHLIKAQSQKKMG
ERAEAIKTLHMAMNLPGMRRIKAPSKSK-HRTEVDISHRLSV-FLELVEVHRLNGEQHEA
AKVLQDAIHEFSGTCEELRVTIANADLALAQGDTECALSMLRNVTPEQAYFTEAKEKMAD
IYLKHRKEKMLYITCYREI---SERMPSP

PF13181 // ENSGT00390000005979_0_Domain_9 (810, 842)

RSFLLLGDAYMNIQEPEEAIVAYEQALNQNP
KDGTLASKIGKALVKTHNYSKAITYYEAAMKSRQQNCLCYDLAELLLKLKLYEKAEKVLQ
HSLAHEP----------------VNELSALMEDGRSQVLLAKVYSKMERPGDAITALQQA
RELQARVLKRVQMEQPDAVPSQKHLAAEICAEIAKHSVAQRDYEKAIKFYREALVHCEKD
NKIMLELAQLYLAQDDIEASLQHCALLLQNDQDNEPAT

PF13174 // ENSGT00390000005979_0_Domain_13 (1059, 1087)

LMMADLMFRKQDYEQAVFHLQQ
LLERKPDNFVTLSRLIDLL-RRCGKLEEVPRFFSMAEKYSSRTKLDPGFQYCKGLHFWYT
GEPNDALRHFNKARKDSDWGQNALYNMIEICLNPDNETIGGEVFENLDGDLGSSSEKQES
VQLAVRTAEKLLKELKPQTIQGHVQLRIMENCCLMATKQKSSVEQALSTFTEIAASEKDH
IPALLGMATAYMILRQTPKARNQLKRIAKMTWNPVDAEDLE

PF13181 // ENSGT00390000005979_0_Domain_15 (1302, 1328)

KSWLLLADIYIQSAKYDVA
EELLKRCLCHNKSCCKAYEYMGYIMEKEQAYTDAAFNYEMAWKHGNQANPAVGYKLAFN-
-YLKAKRY---------VDAIDICHQ-VLKAHPTYPKIRKDILDKARSSLRP

------------------------------------------------------------
-----MDSQGLKTLINYYCQERYYH-HVLLVASEGMKKY-GSDPVFRFYHAYGTLMEGKA
QEALREFEAIKNKQDVSLCSLIALMYVHKMSPNP---DREAILELDTKMKEQRKEAGRKA
LYHAGLFLWHIGRHDKAREYIDRMSKMPH-DSNEGPILKAWLDITRGKEPYAKKALRYFE
EGLQDGNDIFALLGKVLCLEMRQNYSGALETVSQIIVNFPSFLPAFEKKMKLQLALQDWD
QTVETAQRLLLQDSHNVEALRMLALYYLCREGDTEKA--------AAKLENLGNALDIVE
PQNAQLFYKITMAFSRTCGRNQLILQKVQNFLEKAFSLTPQQAEIATELGYQMILQGKVK
EAWKWYRTAMTLNESNISAVTGLIRCQLIEGQLQDADQQLEFFSEFQQSMGKSAELMYLH
AVLATKKNSRQEEVINLLNDAVNTHFSHLEDLPLGIQYFEKLNPDFLLEVVTEYLNFCPI
QPAGPGQPLSPVLRRCSSVLETIIRSVPGLPQAVFLMAKVKYLS---GDI-EAAYNNLQH
CLEHSPSYAEAHLLMAQVYLSQEKVKLCSQSLELCLSYNFNVRDYPLYHLIKAQSQKKMG
EVAEAIKTLHMAMNLPGMRRSRASSKSK-HRTEVDASHRLSI-FLELVEVHRLNGEQHEA
AKVLQDAIHEFSGTCEELRVTIANADLALAQGDTERALSMLRNVTTEQPYFIEAKEKMAD
IYLKHRKEKMLYITCYREI---AERMPSP

PF13181 // ENSGT00390000005979_0_Domain_9 (810, 842)

RSFLLLGDAYMNIQEPEEAIVAYEQALNQNP
KDGTLARKIGKALVKTHNYSKAITYYEAALKSGQQNCLCYDLAELLLRLKLYEKAEKVLQ
HSLAHEP----------------VTELSALMEDGRSQVLLAKVYSKMERPSDAIAALQQA
RELQARILKRVQMEQPDAVPSQKHFAAEICAEIAKHSAAQRDYEKAITFYREALVHCETD
SKIMLELAQLYLAQEDLDASLRHCALLLQRDQDNEPATMLMADLMFRKQDYEQAVFHLQQ
LLERKPDNFMTLSRLIDLL-RRCGKLEDVPRFFSMAEKHNSRTKLEPGFQYCKGLHFWYT
GEPNDALRHFNKARKDSDWGQNALYNMIEICLNPDNETIGGEVFENLDGDLGSSTEKQES
VQLAVRTAEKLLKELKPQTTQGRLQLRILENCCLMATKQKSSVEQALNTFTEIAASEKDH
IPALLGMATAYMILKQTPKARNQLKRIAKMTWNPIEAEDLE

PF13181 // ENSGT00390000005979_0_Domain_15 (1302, 1328)

KSWLLLADIYIQSAKYDMA
EELLKRCLCHNRSCCKAYEYMGYIMEKEQAYTDAAFNYEMAWKHSNQTNPAVGYKLAFN-
-YLKAKRY---------VDAIDICHQ-VLEAHPAYPKIRKDILDKARASLRP

------------------------------------------------------------
-----------------YCQERYFH-HVVLVASEGMKRY-GSDPVFRFYHAYGTLMEGKI
QEALREFEAIKNKQDVSLCSLIALIYAHKMSPNP---DREAILESDARVKEQRKGADQKA
LYYAGLFLWHIGRHDKAREYIERMIKMPN-SSNEGQILKAWLDIARGNEPYAKK------
---------------ARCLEMLQNYSGALETVNQIIVNFPSFLPAFIKKMKLQLALQDWD
QMVETAQRLLLQDNQNVEALRMLALYYLCREGNVEKA--------ATTLEHLGNALDVME
PQNAELFYKVTKAFSRTCGRNQLILQKVQTLLEKAFTLSPQQSEFAAEIGYQMILQGKVK
EALTWYQTAMTLDNTSISALTGFIRSQLMDGQLQEADQQLEFLSEVQQSIEKSTELIYLH
VILAMKKNKQQEEVIHLLNDVLDTHFLQLEDVPLSIQYFETLNPDFLLEIITEYLNFCPM
LPASSGQALAPFFRRCTLVLETIVRTVPGLLQAVFLIAKVKYLS---GNI-EAAFNNLQY
CLDHNPSYADAHLLMAQVYLSQEKFKQCSQSLELCLSYNFDVREYPLYHLIKAQSQKKMG
EITEAVKTLHMAMNLPGMRRTGASSKSQGRKTEVDAAHRLSI-FLELVEVHRLNGEQHEA
AKVLQDAIHEFSGTSEELRVTIANADLALAQGDAEQALRILRNVTAEQPYFIEAKEKMAD
IYLKHRKEKMLYIT---------------------------------SIVAYEQALSQNP
KDGTLASKIGKALVKTH

PF14559 // ENSGT00390000005979_0_Domain_9 (858, 931)

NYSKAITYYEAALKSGQQNYLCYDLAELLLKLKLYEKAEKVLQ
HALAHEP----------------VNELSALMEDGRSQVLLAKVYNKMERPGDAVTALQQA
RELQARVLKRVQMEQPDAVPAQKHLAAEICAEIAKHSVAQQDYEKAIMFYREALVHCETD
NKIMLELARLYLAQGDPDACLRHCMMLLQSDQDNEAATMEICLYL---------------
MYYLFLDNYMTLSRLIDLL-RRCGKFDDIPRFFVMAEKRNPRAKLEPGFQYCKGLYLWYT
GEPNDALRHFNKARKDSEWGQNALYNMIEICLNPDNETIGGEVFENLDGDLGNSTEKQES
VQLAVRTAEKLLKELKPQTIQGHVQLRIMENYCLMATKQKSNVEQALNTFTEIAKSENDH
IPALLGMATAYMILKQTPXXXNQLKRIAKMNWNAIDAEEFE

PF13181 // ENSGT00390000005979_0_Domain_15 (1302, 1329)

KSWLLLADIYIQSAKYDMA
EDLLRQCLRHNRSCCKAYEYMGYIMEKEQAYSDAASNYEMAWKYGNQTNPAVGEFRELGT
GFLQESLFKCGFFFFRIKHTKSQCSL-SF-----------------------

------------------------------------------------------------
-----MDSQGLKTLINYYCQERYFH-HVLLVASEGMKRY-GNDPVFRFYHAYGTLMEGKT
QDALREFEAIKNKQDVSLCSLIALIYAHKMSPNP---DREAILESDAKVKEQRKGAGPKA
LYHAGLFLWHVGHHDKAREYIDRMIKMSN-GSKEGQVLRAWLDITRGKEPYTKKALRYFE
EGLQDGNDIFALLGKAQCLEMRQNYSGALETVNQIIMSFPSFLPAFVKKMKLQLALQDWD
QTVETAQRLMLQDNQNVEGLRMLALYYLCREGDIDKA--------ATKLESLGSALEAME
PQNAQLFYKITIAFSRTCGRSQLILQKLHTFLERAFSLTPQESEFATELGYQLILQGKVQ
EALKWYETAMTLNETSVPALIGFIRCQLIEGQLQDADQQLEFLSEIQQSIGKSAELTYLH
AILAMKKNKRQEEVINLLNDVLDTHFSHLEDSPLGIQYFEKLNPDFLLEIITEYLNFCPM
QPASPGQPLSPLLRRCTSILETIVRTVPGLLQAVFLIAKVKYLS---GDT-EAAYNNLQH
CLEHSPSYADAHLLMAQVYLSQEKFKLCSQSLELCLSYNFKVREYPLYHLIKAQSQKKMG
EIAEAIKTLHMAMSLPGMRRIGASSKSKYRKTEADAGHRLSI-FLELVEVHRLNGEQHEA
AKVLQDAIHEFSGTSEEL

PF07721 // ENSGT00390000005979_0_Domain_8 (739, 762)

RVTIANADLALAQGDVERALSML

ENSGT00390000005979_0_Linker_8_9 (762, 811)

RNVTAEQPYFIEAKEKMAD
IYLKHRKEKMLYITCYREI---AERMPSPR

PF00515 // ENSGT00390000005979_0_Domain_9 (811, 842)

SFLLLGDAYMNIQEPEEAIVAYEQALNQNP
KDGTLASKIGKALVKTHNYSKAITYYEAALKSGQQNYLCYDLAELLLKLKWYDKAEKVLQ
HALAHEP----------------VNELSALMEDGRSQVLLAKVYSKVDRTSDAVTSLQQA
RELQARVLKRVQMEQPDAVPAQKHLAAEICAEIAKHSVAQRDYEKAIKFYREALVHSETD
NKIM

PF07721 // ENSGT00390000005979_0_Domain_12 (1025, 1043)

LELARLYLAQDDPDACLRHCALLLQSDQDNEAATMYLAELMLHKYWMERRVFLSKL
LELSPNYNYMTLSRLIDLL-RRCGKLEDVPRFFLMAEKRNSRAKLEPGFQYCKGLYLWYT
GEPNDALRHFNKARKDSDWGQNALYNMIEICLNPDNETIGGEVFENLDGDLGNSTEKQES
VQLAVRTAEKLLKELKPQTVEGHVQLRIMENYCLMATKQKSNVEQALNTFTEVATSEKDH
IPALLGMATAYMILKQTPRARNQLKRIAKMNWNAVDAEDFEKSWLLLADIYIQSAKYDMA
EELLKRCLRHNRSCCKAYEYMGYIMEKEQAYTDAAFNYEMAWKHGNQTNPAVGYKLAFN-
-YLKAKRY---------VDAIDVCHQ-VLEAHPTYPKIRKDILDKARTSLRP

------------------------------------------------------------
------------------------------------------------------------
--------------------MMALIYAHKKSPNP---DREAILELDARLKEQRKTAGQQA
LYYAGLFLWHLGREDKAREYVDRMIKVSG-GGKEGLILKAWLDLTCGKETHIKKALKYFD
EALQEGNDVFALLGKAQYFEVRQNYSGALEIVNQIIAIFPNFIPAFIKKMKLQLALQDWE
QTIETAHRLLQKDPLNLEAMRMEALHHLCREGNISEA--------SARLGVLIKALDRLE
PRNSELFCKMALAFSRTCGRSQFILQHTQTLVQRAFDLASDNAEFATELGYQMILQGKVK
EALKWYKTAMTLDETSVSALTGIIRCQLIQGQLEDAEQQLEFLNEIQQSIGKSGELSFLR
AVLAMKKHKREEEVFALLNDVLDTHFSSLHGFPLGVEYFEKLNPDFLLEIIREYLNFCPA
QPASPGQSPSPLLKHCASVLETVVKTVPGLQQAVFLIAKVKYLS---GDI-EAAHSNLHY
CLERNPSYADAHLLMAQVYLAQNNTKLCSQSLETCLSYNFEVREHPVYHLIKAQAQKKLG
EIPEAIKTLQMARNLPGMRKPVSSSKTKGKSIEIDTSDRVSV-FLELVEAHRLNGELHEA
AVVIQDAINEFSGTPEELRVVIANADLAIAQGDVKHALTMLRNITPEQPYFVQAKVKMAD
IYLQYKKDKKLYAACYSDL---AEKLPSAHT

PF07719 // ENSGT00390000005979_0_Domain_9 (812, 842)

FLLLGDAYMNIQEPDEAIEVYEQALKKNP
KDPSLASKIGKALIKTHNYSKAINYYEAAVRNGQQNFLCYDLAELLMKLKQYEQAEKVLQ
QALDHEP----------------VNELSSLMEDVRYQVLLAKIYSKMEKIDRAIVSLQQA
RELQGRVLKRAQVEQLDAVPAQKQLAAEICAEIAKHSTAQRNYEKAIKFYKEALVHCESN
NKAMLELARLYLAQDDTDACQHQCSLLLKNDQDNEAATMMMADLMFRKQDYEQAVFHFQQ
LLERKPDNYATLSRLIDLL-RRAGKLEEVPRFLSMAEKHSSRTKLEPGFHYCKGLYLWYT
GEPNDALRHFNKARKDSDWGQNAVYNMIEICLNPDNETVGGEVFENLDADIGNSTEKQES
VQLAVRTAGNLLKELKPQTIQGHIQLRIMENYCLMATKQKSNVEQALNTFTEIVVAEKDH
IPALLGMATAYMILKQTPRARNQLKRISKMSWNPIDAEEFEKSWLLLADIYIQSAKYDMA
GELLKRCLRHNRSCCKAYEYMGYIMEKEQAYKDAAINYEMAWKYGNQTNPTVGYKLAFN-
-YLKGKRY---------VDAIDVCHK-VLKAHPNYPKIRKEILDKARASLRN

------------------------------------------------------------
-----MDSQGLKALINYYCQERYFH-HVLLVASEGMKSY-GSDPVFRFYHAYATLMEGKI
QEALREFEAIKNKQDVSLCSLIALIYAHKMSPNP---DREAILESDARVKEQRKGAGPKV
LYQAGLFLWHVGRHDKAREYIDRMIKISN-GSKEGQVLRAWLDITRRKEPYTKKALRYFE
EGLQDGNDIFALLGKAQCLEMRQNYSGALETVNEIIMNFPSFLPAFVKKMKLQLALQDWD
QTVETAQRLMLQDNQNLEALRMLALYYLCREGDIEKA--------ATQLENLGNALDAVE
PQNAQLFYTITIAFSRTCGRSQLILQKTQTLLERAFNLNPQLSEFATELGYQMILHGKVK
EALKWYKTAMTLDETSVPALVGFIQCQLIEGQLQDADQHLEFLSEVQQSFGKSAELTYLH
AVLAMRKNKRQEEVINLLNDVLDTHFSQLEDLPLGIQYFEKLNPDFLLEIITEYLNFCPM
QPASPGQPLSPLLRRCTSILETIVRTVPGLLQAVFLIAKVKYLS---GDM-EAAYNNLQH
CLEHSPSYADAHLLMAQVYLSQEKFKLCSQSLELCLSYDFKVREYPLYHLIKAQSQKKMG
EIAEAIKTLHMAMNLPGMRRIGSSSKSKYRKTEVDASHRLSV-FLELVEVHRLNGEQHEA
AKVLQDAIHEFSGTSEEL

PF07721 // ENSGT00390000005979_0_Domain_8 (739, 762)

RVTIANADLALAQGDVERALSML

ENSGT00390000005979_0_Linker_8_9 (762, 811)

RNVTAEQPYFIEAKEKMAD
IYLKHRKEKMLYITCYREM---AERMPSPR

PF00515 // ENSGT00390000005979_0_Domain_9 (811, 842)

SFLLLGDAYMNIQEPEEAIVAYEQALNHNP
KDGTLASKIGKALVKTHNYSKAITYYEAALKSGQQNYLCYDLAELLLKLKWYDKAEKVLQ
HALAHEP----------------VNELSALMEDGRFQVLLAKVYSKVDRPDDAVTSLQQA
RELQARVLKRVQIEQPDAVPAQKHLAAEICAEIAKHSVAQRNYEKAIKFYREALVHCETD
NKIM

PF07721 // ENSGT00390000005979_0_Domain_12 (1025, 1043)

LELARLYLLQDDPDACLRHCALLLQSDQDNEAATMMMADLMFRKQDYEQAVFHLQQ
LLERKPDNYMTLSRLIDFL-RRCGKLEDVPRFFLMAEKRNSRAKLEPGFQYCKGLYLWYT
GEPNDALRHFNKARKDSDWGQNALYNMIEICLNPDNETVGGEVFENLDADLGNSTEKQES
VQLAVRTAEKLLKELKPQTVQGQVQLRIMENYCLMATKQKSNVEQALNTFTEIAASEKDH
VPALLGMATAHMILKQTPRARNQLKRIAKMNWNPIDAEDFERSWLLLADIYIQSAKYDMA
EELIKRCLRHNRSCCKAYEYMGYIMEKEQAYMDAALNYEIAWKHGNQTNPAVGYKLAFN-
-YLKAKRY---------VDAIDICHQ-VLEAHPTYPKIRKDILDKARTSLRP

------------------------------------------------------------
-----RDPKRLKALINYYCQEGYFH-HVQTIASEGVKKF-GNDPIFIFYRIYGTLMEGHV
QEALLDLESIKNKPEVSLCTLMALIYAHKKSPNP---DQEVISELDAKLKEQRKTAGQEA
LYFAGLFLWHIGRHEKAREYIDRMIKISN-GSKEGLILRGWIDVTSGKEASIKKAAKYFD
EGLQNGNDVFGLMGKAQYFEVRQNYSGALENVNQIIANFPHFLPAFMKKMKLQLALQDWE
QATETAHRLLQKDALNLEAIKMEAIHHLCREGNIREA--------SSKLSDVISALDKLE
PRNPQLFCKTALVFSRTCGRNPLILQQTQTLVERAFSLASHSADIATELGYQMILQGKVK
EASKWYGTAMALDETSVPALTGIIRSQLMEGKLDDVEQQLEFLNEIQQSIGKSAELSYLR
AVLALKRHKRQEEVITLLNDVLDIHFSCLRGLPLGVEYFEKLNPDFLIEIIKEYLNFCPA
QPAGPGQPPSPLLKPCASVLETLVKTVPGLQQAAYFTAKVKYLA---GNS-EASQSILQH
CIEQDPSYADAHLLMAQVHLSQNNFKLCSQSLELCLSYNFEVREHPVYHLIKAQAQIKMG
EITEAIKTLQMAMNLPGMRNTASSSKSKSKKIEIDGSDRVSI-YLELVEAHRLNGEQHEA
IKVLQDAINEFSGTPEELRVVIANADLALAQEDVEGALTMLRNITPEQTYYVQAKEKMAQ
VYLEYRKDKKLYASCYRDL---VEKMPSSHTFL

PF07719 // ENSGT00390000005979_0_Domain_9 (814, 842)

LLGDAYMNIQEPEEALEVYEQALKKNP
RDGALAHKIGNALIKTHNYAKAISYYEAALKTGQHNFLSYDLAELLLKLNQYDKAENVLQ
QVLDHESGL--------------PQRLRGLLETTQEGVICPRFTQRWE--KELLSFFHQA
RDLQAKVLKRIQIEQLDAVPMQKQLAAEICSEIAKHSATQRNYEKAIKFYKEALVYCETD
NKVMLELARLYLAYDDVDSCQRQCALLLKNDPDNAAAAMWILTVNFNTVIFNSVLMFAYV
YI----LNYVVILLIVSRFKSPSGE---IKQGINKHNKINNNAEIQAAGKDSSPPAVKYT
GEPNDALRHFNKARKDNDWGQNAVYNMIEICLNPDNETMGGEVFEHLDTDTDTSSEKQES
VQLAVRTAEKLLKELKPQTVQGHVQLRIMENYCLVATKQKSNVERALNAFTEVVVNEKDH
VPALLGMAIAYMILKQTPRARNQLKRISKMNWNPIDAEEFEKSWLLLADIYIQSSKYDMA
GELLKRCLRNNRSCCKAYEYMGYIMEKEQAYKDAAANYEMAWKYGNQTNPTIGFKLAFN-
-YLKAKRY---------IDAINVCHKQVLEAHPNYPKIRKEILDKARASLRT

------------------------------------------------------------
-----MDSQELKTLINYYCQERYFH-HVLLVASEGIKRY-GSDPVFRFYHAYGTLMEGKT
QEALREFEAIKNKEDVSLCSLIALVYAHKMSPNP---DREAILESDARVKEQRKGAGEKA
LYHAGLFLWHVGRHDKAREYIDRMIKMSD-GSKQGHILKAWLDITRGKDAYTKKALKYFE
EGLQDGNDTFALLGKAQCLEMRQNYLGALETVNQIIVNFPSFLPAFVKKMKLQLALQDWD
QTVETAQRLLLQDSQNVEALRMQALYYVCREGDIEKA--------STKLENLGNALDAME
PQNAQLFYNITLAFSRTCGRSQLILQKIQTLLERAFSLNPQRSEFATELGYQMILQGTVK
EALKWYKTAMTLDETSVPALVGFIQCQLIEGQLQDADQQLEFLNEIQQSIGKSAELIYLR
AVLAMKKNKRQEEVINILNDVLDTHFSQLEGLPLGIQYFEKLNPDFLLEIVTEYLSFCPM
QPASPGQPLCPLLRRCVSVLEIVVRTVPGLLQTVFLIAKVKYLS---GDI-EAAFNNLQH
CLEHNPSYADAHLLLAQVYLSQEKIKLCSQSLELCLSYDFKVREYPLYHLIKAQSQKKMG
EIADAIKTLHMAMSLPGVKRIGASAKSKDRKTQVDTSHCLSI-FLELIEVHRLNGEQHEA
AKVLQDAIHEFSGTSEEVRVTIANADLALAQEDTERALSILRNVTAEQPYFIEAREKMAD
IYLKHRKDKMLYITCYREI---AERMPNPQSFLLLGDAYLNILEPEEALVAYEQALNQNP
KDGTLASKMGKAFIKT

PF14559 // ENSGT00390000005979_0_Domain_9 (857, 931)

HNYSKAISYYEAALKSGQ-NYLCYDLAELLLKLKWYDKAEKVLQ
QALAHEP----------------VNELSALMEDGRCQVLLAKVYSKMERPGDAITALQQA
QELQARVLKRVRMEQPDAVPAQKHLAAEICAEIAKYS

PF14559 // ENSGT00390000005979_0_Domain_12 (998, 1064)

VAQRDYEKAIKFYREALVHCETD
NKIMLELAQLYLAQDDPDSCLRQCAMLLQSDQDNEAATAMMADLMFRKQDYEQAVFRLQQ
LLERKPDKYMTLSRLIDLL-RRCGKLEDVPRFFSMAEKCNSRMKLEPGFQYCKGQYLWYT
GEPNDALRHFNKARKDSDWGQNALYNMIEICLNPDNETIGGEVFENLDGDLGNSTERQES
VQLAVRTAEKLLKELKPQTIQGQVQLRVLENYCLMATKQKSNVEQALNTFTEIAASEKDH
IPALLGMATAYMILKQTPRARNQLKRIAKMNWNAIDAEEFE

PF13181 // ENSGT00390000005979_0_Domain_15 (1302, 1333)

KSWLLLADIYIQSAKYDMA
EELLKRCLRYNRSCCKAYEYMGYIMEKEQAYTDAALNYEMAWKYSHQTNLAIGYKLAFN-
-YLKAKRY---------VDSIDVCHQ-ILKAHPTYPRIRKDILDKARASLRP

------------------------------------------------------------
------------TLINYYCQERYFH-HVLLVASEGIKRY-GSDPVFRFYHAYGTLMEGKT
QEALREFEAIKNKQDVSLCSLIALIHAHKMSPNP---DREAILESDAIMKEQRKGAG

PF00515 // ENSGT00390000005979_0_Domain_0 (178, 212)

PKA
LYHAGLFLWHIGRHDKAREYVDRMIKMSN-GSKEGQVLRAWLDITRGKEPYTKKALR-FE
EGLQDGNDIFALLGKARCLEMRQNYSGALETVNQIIMNFPSFLPAFVEKMKLQLALQDWD
QTVETAQRLIFQDNQNVEGLRMLALYYLCREGDLEKA--------ATKLGNLENALDVME
PQNAQLFYRITIAFSRMCGRSELILQKTQTLLEKAFSLT-QQ

PF00515 // ENSGT00390000005979_0_Domain_3 (403, 436)

SEFAAELGYQKILQGNVK
EASKWYKTAMTLDET

ENSGT00390000005979_0_Linker_3_4 (436, 571)

SVSALIGLIQCQLIEGQLQEADQQLEFLSEIQQSIGKSAELTYLH
AVLAMKKNKRQEEVINLLNDVLDTHFSHLEDLPLGIQYFEKLNPDFLLEIVTEYMNFCPM
QPASPGQPLSPLLRRCTSILETIVRTVPGL

PF00515 // ENSGT00390000005979_0_Domain_4 (571, 608)

LQAVFLIAKVKYLS---GDI-EAAYNNLQH
CLEHSPSYADAHLLMAQVYLSQEKFRLCSQSLELCLSFNFKVREYPLYHLIKAQSQKKMG
EIAEAIKTLHMAMSLPGMR-IGASTKSKYRNTEVDASHRLSI-FLELVEVHCLNGEQHEA
AKVLQDAIHEFSGTSEE

PF07721 // ENSGT00390000005979_0_Domain_8 (738, 763)

LRVTIANVDLALAQGDVERALSMLRNVTAEQPYFVEAKEKMAA
IYLKHRKEKMLYITCYREI---AERMPSPRSFLLLGDAYMNIQEPEEAIVAYEQALNQSP
KD

PF00515 // ENSGT00390000005979_0_Domain_9 (843, 876)

GTLASKIGKALVKTHNYSKAITYYEAALKSGQQNYLCYDLAELLLKLKWYDKAEKVLQ
NALAHEP----------------VNELSALMED

PF00515 // ENSGT00390000005979_0_Domain_10 (934, 967)

GRSHILLAKVYSKVDRPDDAVASLQQA
RELQAR

ENSGT00390000005979_0_Linker_10_11 (967, 987)

VLKRVQMEQPDAVPAQKHLA

PF07719 // ENSGT00390000005979_0_Domain_11 (987, 1020)

AEICAEIAKHSVAQRDYEKAIKFYREALVHCETD
NKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXNYMTLSRLIDFL-RRCGKLEDVPRFFLMAEKRNSRAKLEPGFQYCKGLYLWYT
GEPNDALRHFNKARKDSDWGQNALYNMIEICLNPDNETIGGEVFENLDGDLGNSTEKQES
VQLAVRTAEKLLKELKPQTIQGHVQLRIMENYCLMATKQKSNVEQALNTFTEIATSEKDH
IPALLGMATAYMILKQTPRARNQLKRIAKMNWNPIDAEDF

PF00515 // ENSGT00390000005979_0_Domain_15 (1301, 1334)

ERSWLLLADIYIQSAKYDMA
EELLKRCLRHNRS

ENSGT00390000005979_0_Linker_15_16 (1334, 1370)

CCKAYEYMGYIMEKEQAYTDAALNYEMAWKQGNQTN

PF00515 // ENSGT00390000005979_0_Domain_16 (1370, 1415)

PAVGYKLAFN-
-YLKAKRF---------VDAIDVCHQ-VLEAHPSYPKIRKDILDKARTSLRP

------------------------------------------------------------
-----MDSQELKTLINYYCQERYFH-HVLLVASEGIKRY-GSDPVFRFYHAYGTLMEGKT
QEALREFEAIKNKQDVSLCSLIALIYAHKMSPNP---DREAILESDARVKEQRKGAGEKA
LYHAGLFLWHIGRHDKAREYIDRMIKMSD-GSKQGHVLKAWLDITRGKDPYTKKALKYFE
EGLQDGNDTFALLGKAQCLEMRQNYSGALETVNQIIVNFPSFLPSFVKKMKLQLALQDWD
QTVETAQWLLLQDSQNVEALRMQALYYVCREGDIEKA--------STKLENLGNALDAME
PQNAQLFYNITLAFSRTCGRSQLILQKIQTLLEKAFSLNPQQSEFATELGYQMILQGRVK
EALKWYKTAMTLDETSVSALVGFIQCQLIEGQLQDADQQLEFLNEIQQSIGKSAELIYLH
AVLAMKKNKRQEEVINLLNDVLDTHFSQIEGLPLGIQYFEKLNPDFLLEIVTEYLSFCPM
QPASPGQPLCPLLRRCVSVLETVVRTVPGLLQTVFLIAKVKYLS---GDI-EAAFNNLQH
CLEHNPSYADAHLLLAQVYLSQEKVKLCSQSLELCLSYDFKVREYPLYHLIKAQSQKKMG
EIADAIKTLHMAMSLPGMKRIGASTKSKDRKTEVDTSHRLSI-FLELIELHRLNGEQHEA
AKVLQDAIHEFSGTSEEVRVAIANADLALAQGDIERALSILQNVTAEQPYFIEAREKMAD
IYLKHRKDKMLYITCFREI---AERMANP

PF13181 // ENSGT00390000005979_0_Domain_9 (810, 842)

RSFLLLGDAYMNILEPEEAIVAYEQALNQNP
KDGTLASKMGKALIKTHNYSMAITYYETALKSGQKNYLCYDLAELLLKLKWYDKAEKVLQ
HALAHEP----------------VNELSALMEDGRCQVLLAKVYSKMERPGDAITALQQA
RELQARVLKRVLMEQPDAVPAQKHLAAEICAEIAKHS

PF14559 // ENSGT00390000005979_0_Domain_12 (998, 1064)

VAQRDYEKAIKFYREALVHYETD
NKIMLELARLYLAQDDPDSCLRQCALLLQSDQDNEAATMMMADLMFRKQDYEQAVFHLQQ
LLERKPDNYMTLSRLIDLL-RRCGKLEDVPRFFSMAEKRNSRAKLEPGFQYCKGLYLWYT
GEPNDALRHFNKARKDRDWGQNALYNMIEICLNPDNETIGGEVFENLDGDLGNSTEKQES
VQLAVRTAEKLLKELKPQTVQGHVQLRIMENYCLMATKQKSNVEQALNTFTEIAASEKDH
IPALLGMATAYMILKQTPRARNQLKRIAKMNWNAIDAEEFE

PF13181 // ENSGT00390000005979_0_Domain_15 (1302, 1329)

KSWLLLADIYIQSAKYDMA
EELLKRCLRHNRSCCKAYEYMGYIMEKEQAYTDAALNYEMAWKYSNRTNPAVGYKLAFN-
-YLKAKRY---------VDSIDICHQ-VLEAHPTYPKIRKDILDKARASLRP

------------------------------------------------------------
-----REQEGGKTLINYYCQERYFH-HVLLVASEGIKKY-GNDPVFRFYHAYGTLMEGKT
QEALREFETLKNKPDVSLCSLLALIYAHKMSPNP---DREAILESDAKVKELRKGAE

PF00515 // ENSGT00390000005979_0_Domain_0 (178, 212)

PRA
LYHAGLFLWHLGRHEKAREYIDRMIKMSD-GSKEGQILRAWLDITRGKEPYTKRALRSFE
EGLQNGNDIFALLGKVQCLEMRQNYLGALETVNQIIVNFPSFLPALVQKMKLQLALQDWD
QAIEIVQRLMLQDKQNVEALRMLALYYLCREGDIEKA--------ATTLENLENALDAME
PQNAQLFYKITIAFSRTCGRNQLILEKVQTLLERAFSLTPQQSEYATELGYLMLLQEKVK
EAWKWYQIAINLEETSITAVIGCIRCQLIEGQLQEADQQLEFLSEIQQSFGKYAELTYLQ
AILAIKKNKRQEEVINLLNDALDTHFSQLQDLPFGIQYFEKLNSDFLLEIITEYLNYCPL
QPASPGQPLSPLLKRCTSVLEAIVRTVPGLLQAVFLIAKVKYLS---GKDTNISYNYIDL
FFPHSPSKAECLLLMTKVYLSQDKFKLCSQSLELCLSYNFKVREYPLYHLIKAQSQKKMG
EIGEAIKTLHMAMSLPGVRTIEASSKSKYKNTEVDASHRLSI-FLELVEVYCLNGEQHEA
AKVLQDAIHEFSGTYEE

PF07721 // ENSGT00390000005979_0_Domain_8 (738, 763)

LRVTIANADLALAQGDVERALSMLQNVTSEQPYFIEVKEKMAD
IYLKHRKEKMLYITCYREI---AEIMPSPHSFLLLGDAYMNIQEPEEAIVAYEQALNQNP
KD

PF00515 // ENSGT00390000005979_0_Domain_9 (843, 877)

GTLASKVGKALVKTHNYSKAITYYEAALKNGQ-NYLCYDLAELLLKLKWYDKAEKVLQ
HALAHEL----------------VNELSAVMED

PF00515 // ENSGT00390000005979_0_Domain_10 (934, 967)

GRLQVLLAKVYSKMERPGDAITSLQQA
RELQAR

ENSGT00390000005979_0_Linker_10_11 (967, 987)

VLKRVQMEQPDAVPAQKHLA

PF00515 // ENSGT00390000005979_0_Domain_11 (987, 1020)

AEICAEIAKHSVAQRDYEKAIKFYREALVHCETD
NKIMLELARLYLAHDDPEACLRHCALLLQSDQDN

PF07719 // ENSGT00390000005979_0_Domain_13 (1055, 1088)

EAATMMMADLMFRKQDYEQAVFHLQQ
LLERKPDNYMTLSRLIDFL-RRCGKLEDVPRFFLMAEKRNSRAKLEPGYQYCKGLYLWYT
GEPNDALRHFNKARKDSEWGQNALYNMIEICLNPDNETVGGEVFENLDRDLGNSTEKQES
MQLAVRTAEKLLKELKPQTAEGHVQLRVLENYCLMATKQKSNVEQALNTFTEIATSEKDH
IPALLGMATAYMILKQTPRARNQLKRIAKMNWNPVDAEDF

PF00515 // ENSGT00390000005979_0_Domain_15 (1301, 1334)

ERSWLLLADIYIQSAKYDMA
EELLKRCLHHNKS

ENSGT00390000005979_0_Linker_15_16 (1334, 1370)

CCKAYEYMGYIMEKEQTYTDAALNYEMAWKHGNQTN

PF00515 // ENSGT00390000005979_0_Domain_16 (1370, 1415)

PAIGYKLAFN-
-YLKAKRY---------VDAIDICHQ-VLEAHPTYPKIRKDILDKARTSLRP

------------------------------------------------------------
--MVVSVLVPTQTLINYYCKERYFR-HILLAASEGIKRY-GSDPVFRFFHAYGILMEGKV
QEALREFEALKNKQDVSLCSLLALIYAHKMSPNP---DREAILEADARLKDQRKGAGQRA
LYHAGLFLWHIGRHEKAREYIDRMIKMSD-GSKEGVILKAWLDVTRGKEPYTKKALRCFE
EILEDGNDIFALLGKAQCLEMRQNYSGALDTVNQIIVNFPSFLPAFVKKMKLQLALQDWD
QTVETAQRLLLQDSQNVEALRMLALYYLCREGDIEKA--------STKLEKLENALDAME
PQNDQLFYKITLAFSRTCGRSQPILQKLQTLLERAFSLNSQQPEYAIELGYQMILQGKIK
EAVKWYKNAMILDESNISSLFGIIQCQLIEGQIEEADQQLEFFSAVQQSLGKSAELTYLH
AILAMKKNKRQEEVINLLNDVLDIHFSHLEDLPLGIQYFEMLNPDFLLEIVKEYLNFCPM
QPASPGQPVTPLLRRCTSALEVIVRTVPGLLQAVFLIAKVKYLS---GDN-EAAYNNLQH
CLERNPSYADAHLLMAQVYLSQEKFKLCSQSLELSLSYNFKVREYPLYHLIKAQSQKKMG
EITEAIKTLHMAMNLPGMRRIGALSKSKYRKNEVDTSHRLSI-FLELVEVHRLNGEQHEA
AKVLQDAIHEFSGTSEELRVTIANADLALAQGDTERALSMLRNVTTEQPYFIEAKEKMAD
IYLKHRKEKMLYITCYREI---AERMPNPRSFLLLGDAYMNIQEPEEAIVAYEQALNQNP
KDGTLASKIGKALVKT

PF14559 // ENSGT00390000005979_0_Domain_9 (857, 931)

HNYSKAITYYEAALKSGQQNYLCYDLAELLLKLKWYDKAEKVLQ
HALAHEP----------------VNELSALMEDGRSQVLLAKVYSKMEKPGDAVTSLQQA
RELQARVLKRVQMEQPDAVPAQKHLAAEICAEIAKHS

PF14559 // ENSGT00390000005979_0_Domain_12 (998, 1064)

VAQRDYETAIKFYREALVHCETD
NKIMLELARLYLAQDDLNACQRHCELLLQSDQDNEAATMMMADLMSRKQDYEQAVFHLQQ
LLERKPDNYMTLSRLIDLL-RRCGKLEDVPRFFLMAEKCNPRAKLEPGFQYCKGLYLWYT
GEPNDALRHFNKARKDSDWGQNALYNMIEICLNPDNETIGGEVFENLDGDLGNSSEKQES
VQLAVRTAEKLLKELKPQTTQGHTQLRIMENCCLMATKQKSNVEQALNTFTEIATSEKDH
IPALLGMATAYMILKQTPRARNQLKRIAKMNWNPIDAEEFE

PF13181 // ENSGT00390000005979_0_Domain_15 (1302, 1329)

KSWLLLADIYIQSAKYDMA
EELLKRCLRHNRSCCKAYEYMGYIMEKEQAYTDAALNYEMAWKHGNQTNPAVGYKLAFN-
-YLKAKKY---------VDAIDVCHQ-VLEAHPSYPKIRKDILDKARTSLRP

------------------------------------------------------------
-----MDVQALKTLIDYYCQERFFH-HVVIAASEGIKKY-AGDPIFRFYHAYGSLMEGKN
QDAVRELEAIKNKQDVSLCSLIALIYAHKKSSNP---DQEAILELDANMKEHRKTAGSKA
LYYAGLFLWHIGRHDKAREYIDRMIKISN-GSKEGLVLRAWLDITNGKEAYAKKALRNFE
EGIQDGNDIFAMLGKAHYLEIRQNYSGALETINQITLNLPSFLPAFVKKMKLQLALQDWD
QTVETAQRIIQQDNQNVESLRMLALYHLCREGNIQEA--------ANKLGDLIRALDIME
PHNAQLFYNMALTFCRTCGRNQFILQKTQVLVERAFGLTPHDAEFATELGYQMILQGKVK
EALKWYKTAMTLDETSVSALIGIIRCQLIEGQIQDAGHQLEFLNEIQQSIGKTAELTFLH
AVLAMKEHKPQEEVINLLNDVLDTHFSNLQALPFGIQYFEKLNPDFLLEIVTEYLNFCPT
QPASPGQPPSLLLRHCTSVLETIVRTVPGLLQAVFLIAKVKYLS---GDI-EASYSNLQH
CLEHNPSYADAHLLMAQVYLSQDNFKLCSQSLELCLSYNFEIREYPLYHLIKAQTQKKMG
QIAEAVKTLHMAMSLPGMRRIGASK-FKSQKYEVDASHRLSV-FLELVDAHRLNGEQHEA
AKILQDAINEFSGTPEEL

PF07721 // ENSGT00390000005979_0_Domain_8 (739, 762)

RVTIANADLALAQGEVERALSML

ENSGT00390000005979_0_Linker_8_9 (762, 813)

RNVTPEQPYFIQTKEKMAD
IYLKHRKEKKLYASCYRDL---VEKLPSPHTF

PF07719 // ENSGT00390000005979_0_Domain_9 (813, 842)

LLLGDAYMNIQEPEEAIEAYEQALKQNP
KDGILASKIGKALVKTHNYSKAITYYEAALKSGQQNFLCCDLAELLLKLKHYEKAEKVLQ
HALAHEP----------------VNELSTLIEDGRYQVLLAKVYSKMEKPAEAIIALQQA
RELQARVLKRVQMEQPDAVLTQKQFAAEICTEIAKHSAIQRDYEKSIKFYKEALVHCETD
SKAMLELARLYLALDDPVACQRHCALLLKNDQDNEAATMMMADLMFRKQDYEQAVFHFQQ
LLERKPDNYTTLSRLIDLL-RRAGKFEDVPRFLLMAEKYSARAKMEPGFQYCRGLYLWYT
GEPNEALRHFNKARKDSDWGQNAVYNMIEICLNPDNETVGGEVFENLDGDLGNSTAKQES
VRLAVQTAEKLLKELKPQTVQGQTQLRIMENYCLMATKQKANVERALNTFTDIATSEKDH
IPALLGMATAYMILKQIPRARNQLKRISKMNWNPIDAEEFEKSWLLLADIYIQSAKYDMA
GELLRRCLRHNRSCCKAYEYMGYIMEKEQAYKDASVNYEMAWKYGNQISPAVGYKLAFN-
-YLKGKRY---------VDAIDICHK-VLKTHPTYPKIRKDILDKARAALRT

------------------------------------------------------------
-----MDSQGLQTLINYYCQERYFH-QVLLVASEGIKRY-GNDPVFRFYHAYGTLMEGKT
QEALREFEAIKNKQDVSLCSLIALINAHKRSPNP---DREAILESDARLKEQRKGAGLKA
LYHAGLFLWHIGHHDKAREYIDRMIKMSN-GSKEGQILRGWLDITRGKDSYTKKALRYFE
EGLQDGNNIFALLGKAQCLEMRQNYSGALETVNQIIMNFPSFLPAFIKKMKLQLALKDWD
QVVETAQRILLQDNQNVEALRMLALYHLCRDGDIEKA--------ATKLENLGNALDAME
PQNAQLFYKITVAFSRTCGRSQLILQKTQTLVERAFNLTPQESEFATELGYHLVLQGKVK
EALKWYNASLTLGENNVSALIGCIQCQLIEGQLQEAEHQLEFLREIQQSIGKPAELTYLH
AILAMKKNKRQEEVINLLNDALDTHFSHLEDLPLGIQYFEKLNPDFLLEIITDYLNFCPM
QPASPGKPLSPFLRRCTSVLETIVRTVPGLLQAVFLIAKVKYLS---GDI-EAAYNNLQH
CLERSPSYADAHLLMAQVYLSQEKFKLCSQALELCLSYDFKVREYPLYHLIKAQSQKKMG
EITEAIKTLRMAMNLPGMR-TGASSKSKCTKTEVDASHRLSI-FLELVEVHRLNGEQHEA
AKVLQDAIHEFSGTSEELRVTIANADLALAQGDVERALSMLRNVTVEQPYFIEAKEKMAD
IYLKHRKEKMLYITCYREI---AERMPSPRSFLLLGDAYMNIQEPEEAIVAYEQALNQNP
KDGTLASKIGKALVKT

PF14559 // ENSGT00390000005979_0_Domain_9 (857, 931)

HNYSKAITYYEAALKSGQQNYLCYDLAELLLKLKLYDKAEKVLQ
HALAHEP----------------VNELSALMEDGRSQVLLAKVYSKVNRPGDAVTSLQQA
RELQARVLKRVQMEQPDAVPAQKHLAAEICAEIAKHSVAQRDYEKAIKFYREALVHCETD
NKIMLELARLYLAQDDPEACLRHCALLLQSDRDNEAATMMVADIMFRKQDYEQAVFHLQQ
LLERKPDNYKTLSRLIDLL-RRCGKLEDVPRFFSMAEKRNSRAKLEPGYQYCKGLYLWYT
GEPNDALRHFNKARKDCDWGQNALYNMIEICLNPDNETVGGEVFENLDRDLGNSSEKQES
VQLAVRTAEKLLKELKPQTVDGHVQLRIMENYCLMATKQKSNVEQALNTFTEIATSEKDH
IPALLGMATAYMILKQTPRARNQLKRIAKMNWNPIDAEDFE

PF13181 // ENSGT00390000005979_0_Domain_15 (1302, 1329)

RSWLLLADIYIQSAKYDMA
EELLKRCLRHNRSCCKAYEYMGYIMEKEQAYADAALNYEMAWKHGNQANPAVGYKLAFN-
-YLKAKRY---------VDAIDVCHQ-VLKAHPAYPKIRKDILDKARACLRP

------------------------------------------------------------
-----MDSQELKTLINYYCQERYFH-HVLLVASEGIKRY-GSDPVFRFYHAYGTLMEGKT
QEALREFEAIKNKQDVSLCSLLALIYAHKMSPNP---DREAILESDARVKEQRKGAGEKA
LYHAGLFLWHIGRHDKAREYIDRMIKISD-GSKQGHVLKAWLDITRGKEPYTKKALKYFE
EGLQDGNDTFALLGKAQCLEMRQNYSGALETVNQIIVNFPSFLPAFLKKMKLQLALQDWD
QTVETAQRLLLQDSQNVEALRMQALYYVCREGDIEKA--------STKLENLGNALDAME
PQNAQLFYNITLAFSRTCGRSQLILQKIQTLLERAFSLNPQQSEFATELGYQMILQGRVK
EALKWYKTAMTLDETSVSALVGFIQCQLIEGQLQDADQQLEFLNEIQQSIGKSAELIYLH
AVLAMKKNKRQEEVINLLNDVLDTHFSQLEGLPLGIQYFEKLNPDFLLEIVMEYLSFCPM
QPASPGQPLCPLLRRCISVLETVVRTVPGLLQTVFLIAKVKYLS---GDI-EAAFNNLQH
CLEHNPSYADAHLLLAQVYLSQEKVKLCSQSLELCLSYDFKVRDYPLYHLIKAQSQKKMG
EIADAIKTLHMAMSLPGMKRIGASTKSKDRKTEVDTSHRLSI-FLELIDVHRLNGEQHEA
TKVLQDAIHEFSGTSEEVRVTIANADLALAQGDIERALSILQNVTAEQPYFIEAREKMAD
IYLKHRKDKMLYITCFREI---AERMANPRSFLLLGDAYMNILEPEEAIVAYEQALNQNP
KDGTLASKMGKALIKTHNYSMAITYYEAALKTGQKNY

PF13181 // ENSGT00390000005979_0_Domain_9 (878, 903)

LCYDLAELLLKLKWYDKAEKVLQ
HALAHEP----------------VNELSALMEDGRCQVLLAKVYSKMERLGDAITALQQA
RELQARVLKRVQMEQPDAVPAQKHLAAEICAEIAKHS

PF14559 // ENSGT00390000005979_0_Domain_12 (998, 1064)

VAQRDYEKAIKFYREALVHCKTD
NKIMLELARLYLAQDDPDSCLRQCALLLQSDQDNEAATMMMADLMFRKQDYEQAVFHLQQ
LLERKPDNYMTLSRLIDLL-RRCGKLEDVPRFFSMAEKCNSRAKLEPGFQYCKGLYLWYT
GEPNDALRHFNKARKDRDWGQNALYNMIEICLNPDNETVGGEVFENLDGDLGNSTEKQES
VQLAVRTAEKLLKELKPQTVQGHVQLRIMENYCLMATKQKSNVEQALNTFTEIAASEKEH
IPALLGMATAYMILKQTPRARNQLKRIAKMNWNAIDAEEFE

PF13181 // ENSGT00390000005979_0_Domain_15 (1302, 1329)

KSWLLLADIYIQSAKYDMA
EELLKRCLRHNRSCCKAYEYMGYIMEKEQAYTDAALNYEMAWKYSNRTNPAVGYKLAFN-
-YLKAKRY---------VDSIDICHQ-VLEAHPTYPKIRKDILDKARASLRP

------------------------------------------------MDS---------
--------QGLKALINYYCQERYFH-HVLLVASEGMKSY-GSDPVFRFYHAYATLMEGKI
QEALREFEAIKNKQDVSLCSLIALIYAHKMSPNP---DREAILESDARVKEQRKGAGPKV
LYHAGLFLWHIGRHDKAREYIDRMIKISN-GSKEGQVLRAWLDITRRKEPYTKKALRYFE
EGLQDGNDIFALLGKAQCLEMRQNYSGALETVNQIIMNFPGFLPAFVKKMKLQLALQDWD
QTVETAQRLMLQDNQNLEALRMLALYYLCREGDIEKA--------ATQLENLGNALDAVE
PQNAQLFYTITIAFSRICGRSQLILQKTQTLLERAFSLNPQQSEFATELGYQMILHGKVK
EALKWYKTAMTLDETSVSALIGFIQCQLIEGQLQDADQHLEFLREVQQSIGKSAELTYLH
AVLAMRKNKRQEEVINLLNDVLDTHFSQLEDLPLGIQYFEKLNPDFLIEIITEYLNFCPM
QPASPGQPLSPLLRRCTSILETIVRTVPGLLQAVFLIAKVKYLS---GDI-EAAYNNLQH
CLEHSPSYADAHLLMAQVYLSQEKFKLCSQSLELCLSYNFKVREYPLYHLIKAQSQKKMG
EIAEAIKTLHMAMSLPGMRRIGSSSKTKYRKTEVDASHRLSV-FLELAEVHRLNGEQHEA
AKVLQDAIHEFSGTSEEL

PF07721 // ENSGT00390000005979_0_Domain_8 (739, 762)

RVTIANADLALAQGDVERALSML

ENSGT00390000005979_0_Linker_8_9 (762, 811)

QNVTAEQPYFIEAKEKMAD
IYLKHRKEKMLYITCYREM---AERMPSPR

PF00515 // ENSGT00390000005979_0_Domain_9 (811, 842)

SFLLLGDAYMNIQEPEEAIVAYEQALNHNP
KDGTLASKIGKALVKTHNYSKAITYYEAALKSGQQNYLCYDLAELLLKLKWYDKAEKVLQ
HALAHEP----------------VNELSALMEDGRFQVLLAKVYSKVDRPDDAVTSLQQA
RELQARVLKRVQMEQPDAVPAQKHLAAEICAEIAKHSVAQRNYEKAIKFYREALVHCETD
NKIM

PF07721 // ENSGT00390000005979_0_Domain_12 (1025, 1043)

LELARLYLLQDDPDACLRHCALLLQNDQDNEAATMMMADLMFRKQDYEQAVFHLQQ
LLERKPDNYMTLSRLIDFL-RRCGKLEDVPRFFLMAEKRNSRAKLEPGFQYCKGLYLWYT
GEPNDALRHFNKARKDSDWGQNALYNMIEICLNPDNETVGGEVFENLDADPGNSTEKQES
VQLAVRTAEKLLKELKPQTVQGQVQLRIMENYCLMATKQKSNVEQALNTFTEIAASEKDH
VPALLGMATAHMILKQTPRARNQLKRIAKMNWNPIDAEDFERSWLLLADIYIQSAKYDMA
EELIKRCLRHNRSCCKAYEYMGYIMEKEQAYMDAALNYEMAWKHGNQTNPAVGYKLAFN-
-YLKAKRY---------VDAIDVCHQ-VLEAHPTYPKIRKDILDKARTSLRP

------------------------------------------------------------
-----MDSQELKTLINYYCQERYFH-HVLLVASEGMKRY-GSDPVFRFYYAYGTLMEGKA
QEALREFEAIKNKQEVSLCSLIALIFAHKMSPDP---DREAILESDARVKELRKGAGE

PF13181 // ENSGT00390000005979_0_Domain_0 (179, 208)

KA
LYHAGLFLWHLGRHDKAKEYIDRMIKM

ENSGT00390000005979_0_Linker_0_1 (208, 251)

SD-GSKEGQVLKAWLDITRGKDSSTKKALRYFE
EGLQDRNDTF

PF13174 // ENSGT00390000005979_0_Domain_1 (251, 281)

ALLGKAQCLEMRQNYSGALETLNQIIVNFPNFFPAFIKKMKLQLTLQDWD
QTVETSQRLLLQDNQNVEALRMLALYYLCREGDIEKA--------STKLDNLGNALDAME
PQNAQLFYNITLAFSRTCGRSHVILQKIQTLLEKAFNLNSQKSEFATELGYQMILQGKVK
EALKWYKIAMTIDETSISALIGFIRCQLIEGQLQDADQQLEFLSEIQQSIEKSAELTYLH
AVLAIKKNKRQEEVINLLNNVLDTHFSHVEDLPLGIQYFEKLNPDFLLEIITEYLNFCPA
QPASPGQPLSPVLRRCTSVLETVVRIVPGLLRAVFLLAKVKYLS---GNN-EAALNKLKH
CLEHNPSYAEAHLLMAQVYLSQEKFKLCSQSLELCLSYDFKVREYPLYHLIKAQSQKKMG
EIAEAIKTLHMAMSIPGMKKIGTSSKSKSGKTEIDTGHRLSL-FLELVEVHRLNGEQHEA
AKVLQDAIHEFSGTSEELRVTIANAELALAQGDTERALSMLQNVTAEQPYFIEAKEKMAD
IYLKHRKDKMLYITCYREI---AERKPDPS

PF13181 // ENSGT00390000005979_0_Domain_9 (811, 842)

SFLLLGDAYMNIQEPEEAIIAYQQALNQNP
KDGTLASKIGKALVKTHNYSKAITYYEAALKNGQQNYLCYDLAELLLKLKWYDKAEKVLQ
HAVAHEP----------------VNELSALMEDARSQVLLAKVYSKMGGLGDALTSLHEA
RELQARVLKRVQMEQPDAVSTQKHLAAEICAEIAKHS

PF14559 // ENSGT00390000005979_0_Domain_12 (998, 1062)

VAQRDYEKAIKFYREALAHCVTD
NKILLELARLYLAQDEPDACLRHCALLLQTDQDNEAATTMMADVMFRKQDYEQAVFHLQQ
LLERKPDNYMTLSRLIDLL-RRCGKLEDVPRFFLMAEKRNSRAKLEPGFLYCKGLYLWYT
GEPNDALRHFNKARKDSDWGQNALYNMIEICLNPDNETIGGEVFENLDGDLGNSSEKQES
VQLAVRTAEKLLKELKPQTVQGHLQLRIMENYCLMATKQKSNVEQALNTFTAIASSEKDH
IPALLGMATAYMILKQTPKARNQLKRISKMNWNAIDAEEFE

PF13181 // ENSGT00390000005979_0_Domain_15 (1302, 1329)

KSWLLLADIYIQSAKYDMA
EELLKQCLRHNRSCCKAYEYMGYIMEKEQAYTDAAFNYEMAWKHSNQTNPVVGYKLAFN-
-YLKAKRY---------VDSVDICHQ-VLEAHPNYPKIRKEILDKARTCLRP

------------------------------------------------------------
-----FRLPMLKKLKHYSVQAKYFL-KVYAAAEEALGRL-GGHPVFHFYRAYGDLRTGDI
QEGIRQLETIKNKQEVSLCVLMALIYAHKMSPNP---DRDAILELDTKMKEQRKTAGQQA
LYFAGLFLWHLGREDKAREYVDRMIKVSN-GDKEGLILKAWLDLTCGKETHIKKAVKYFD
EALQEGNDVFALLGKAQYFEVRQNYSGALEIVNQIIASFPNFIPAFIKKMKLQLALQDWE
QTVETAHRLLQKDALNLEAIRMEALHFLCREGNIPQA--------SARLGDLVKALDKLE
PRNSQLFCKMALAFSRTCGRNQLILQHTQTLVERAFDLTSDN

PF00515 // ENSGT00390000005979_0_Domain_3 (403, 436)

AEFATELGYQMILQGKVK
EALKWYKTAMTLDETSVSALTGIIRCQLIQGQLEDAEQQLEFLNEIQQSIGKSGELSFLR
AVLAMKKHKRQEEVIALLNDVLDTHFSSLRGFPLGVEYFEKLNPDFLLEIIREYLNFCPA
QPACHGQSPSSLLKHCASVLETVVKTVPGLQQAIFLIAKVKYLTDFLGDI-EAAYNNLHY
CLERNPSYADAHLLMAQVYLAQNNTKLCSQSLELCLSYNFEVREH

PF00515 // ENSGT00390000005979_0_Domain_7 (646, 672)

PVYYLIKAQTQKKMG
EISEAIKTLQM

ENSGT00390000005979_0_Linker_7_8 (672, 738)

ARNLPGMRKHTASSKTKAKRIEIDANDRVSV-FLELVEAHCLNGELHEA
AIVLQDAINEFSGTPEE

PF07721 // ENSGT00390000005979_0_Domain_8 (738, 763)

VRVLISNADLAVAQGDVEQALTVLRNITPEQPYFVQAKIKMAD
TYLQYRRDKKLYAGCYRDL---VEKLPSAHTLLLLGDAYMNIQEPDEAIEVYEQALKKST
KD

PF00515 // ENSGT00390000005979_0_Domain_9 (843, 876)

PASASKIGNALPKTHNYSKAISYYEAALRNGQQNFLCYDLAELLMKLKQYEKAEMVLQ
QALDHEP----------------VNELSSMMED

PF00515 // ENSGT00390000005979_0_Domain_10 (934, 967)

GRYQLLLAKIYSKMEKTDETIASLQQA
RELQAR

ENSGT00390000005979_0_Linker_10_11 (967, 987)

ILKRSQIEQPDVVPAQKQLA

PF00515 // ENSGT00390000005979_0_Domain_11 (987, 1020)

AEICTEIAKHCTAQRNYEKAIKFYKEALVHCETD
KKAMLELARLYLAQDDADACQHQCSLLLKNDQDN

PF07719 // ENSGT00390000005979_0_Domain_13 (1055, 1088)

EAATMMMADLMFRKQDYEQAVFHFQQ
LLERKPD

ENSGT00390000005979_0_Linker_13_14 (1088, 1127)

NYATLSRLIDLL-RRAGKLEEVPRFLLMAEKHSSRTKLE

PF00515 // ENSGT00390000005979_0_Domain_14 (1127, 1153)

PGFHYCKGLYLWYT
GEPNDALRHFNK

ENSGT00390000005979_0_Linker_14_15 (1153, 1301)

ARKDNDWGQNAVYNMIEICLNPDNETVGGEVFENLDGDISNSTEKQES
VQLAVRTAENLLKELKPQTSQGHIQLRIMENYCLMATKQKSNVERARNTFTEIVVAEKDH
IPALLGMATAYMILKQTPRARNQLKRIAKMNWNPIDAEEF

PF00515 // ENSGT00390000005979_0_Domain_15 (1301, 1334)

EKSWLLLADIYIQSSKYDMA
GELLKRCLRHNRS

ENSGT00390000005979_0_Linker_15_16 (1334, 1370)

CCKAYEYMGYIMEKEQAYKDAAMNYEMAWRYGNQTN

PF00515 // ENSGT00390000005979_0_Domain_16 (1370, 1415)

PTIGYKLAFN-
-YLKGKRY---------VDAITICHK-VLEAHPNYPKIRKEILDKARALLRT

------------------------------------------------------------
-----MDSEVLKTLINYYCKERYFH-HMLLVASEGIKRY-GSDPVFRFFHAYGILMEGKV
QEALREFEALKNKQDVSLCSLLALIYAHKMSPNP---DREAILEADARLKDQRKGAGQKA
LYHAGLFLWHVGRPEKAREYIDRMIKMSD-GSKEGHILKAWLDITRGKEPYTKKALRCFE
EILEDGNDIFALLGKAQCLEMRQNYSGALDTVNQMIVNFPSFLPAFVKKMKLQLALQDWD
QTVETAQSYLALWYDNLISHLSREICSLFIGNDIW-R--------PQFGQKLENALDAME
PQNDQLFYKITLAFSRTCGRSQPILQKLQTLLERAFSLNSQRPEFAIELGYQMILQGKIK
EAVKWYKSAMALDESSISSLFGFIQCQLIEGQIEEADQQLEFFSAVQQSMGKSAELTYLH
AILAMKKNKRQEEVINLLNDVLDIHFSHLEDLPLGLQYFEKLNPDFLLEITFNT---VYL
SPASPGQPVTPLLRRCTSALEVIVRTVPGLLQAVFLIAKVKYLS---ENHIKCTFY----
--------------------------IC-------MDNE------------------LLG
K---------------------------Y---------NNNI-F--------ISFLQHEA
AKVLQDAIHEFSGTSEELRVTIANADLALAQGDTERALSMLRNVTAEQPYFIEAKEKMAD
IYLKHRKEKMLYITCYREI---AERMPNP

PF13181 // ENSGT00390000005979_0_Domain_9 (810, 842)

RSFLLLGDAYMNIQEPEEAIVAYEQALNQNP
KDGTLASKIGKALVKTHNYSKAITYYEAALKSGQQNYLCYDLAELLLKLKWYDKAEKVLQ
HALAHEP----------------VNELSALMEDGRSQVLLAKVYSKMERPGDAITSLQQA
RELQARVLKRVQMEQPDAVPAQKHLAAEICAEIAKHSVAQRDYETAIKFYREALVHCETD
NKVTKDIKC--------------CQYL---------------------------------
KYYLFLDNYMTLSRLIDLL-RRCGKLEDVPRFFLMAEKCNPRAKLEPGFQYCKGLYLWYT
GEPNDALRHFNKARKDSDWGQNALYNMIEICLNPDNETIGVPF-DTL---SLFKKILQES
VQLAVRTAEKLLKELKPQTIQGHIQLRIMENCCLMATKQKSNVEQALNTFTEIATSEKDH
IPALLGMATAYMILKQTPRARNQLKRIAKMNWNPIDAEEFE

PF13181 // ENSGT00390000005979_0_Domain_15 (1302, 1329)

KSWLLLADIYIQSAKYDMA
EELLKRCLRHNRSCCKAYEYMGYIMEKEQAYTDAALNYEMAWKHGNQMNPAVGYKLAFN-
-YLKAKKY---------VDAIDVCHQ-VLEAHPSYPKIRKDILDKARTSLRP

------------------------------------------------------------
------------TLINYYCQERYFH-HVLLVASEGIKRY-SNDPVFRFYHAYGTLMEGKI
QEALREFEAIKNKQDISLCSLIALIYAHKMSPNP---DREAILESDAKVKEQRKGAG

PF00515 // ENSGT00390000005979_0_Domain_0 (178, 212)

PKA
LYHAGLFLWHVGRHDKAREYIDRMIKMSN-G

ENSGT00390000005979_0_Linker_0_1 (212, 249)

SKEGQVLRAWLDITRGKEPYTKKALRYFE
EGLQNGND

PF00515 // ENSGT00390000005979_0_Domain_1 (249, 282)

IFALLGKAQCLEMRQNYSGALETVNQIIVNFPSFLPAFVQKMKLQLALQDWD
QTIEIAQRLMLQDKQNVEALRMLALYYLCREGDIEKA--------ATTLENLGDALDAME
PQNAPLFYKITIAFSRTCGRNQLILQKIQTFLERAFSLNPQQSEYAAEFGYQMILQGKVK
EASKWYKTAMALDETSVSALIGFIRCQLIEGQLQDADQQLEFLSEIQQSIGKSAELTFLH
ALLAMKKNKRQEEVINLLNDVLDTHFSHLEDLPLGIQYFEKLNPDFLLEIITEYLNFCPM
QPASPGQPLSPLLRRCTSILETIVRTVPGL

PF00515 // ENSGT00390000005979_0_Domain_4 (571, 608)

LQAVFLIAKVKYLS---GDI-EAAYNNLQH
CLEHSPSYADAHLLMAQVYLSQENFKLCSQSLELCLSYNFKVREYPLYHLIKAQSQKKMG
EIAEAIKTLHMAMSLPGMRNIGASSKSKYKKTEVDASHRLSI-FLELVEVHRLNGEQHEA
AKVLQDAIHEFSGTSEE

PF07721 // ENSGT00390000005979_0_Domain_8 (738, 763)

LRVTIANADLALAQGDVERALSMLR

ENSGT00390000005979_0_Linker_8_9 (763, 825)

NVTSEQPYFIEAKEKMAD
IYLKHRKEKMLYITCYXXX---XXXXXXXXXXXXXXXXXXXXXX

PF00515 // ENSGT00390000005979_0_Domain_9 (825, 842)

PEEAIVAYEQALNQNP
KDGTLASKIGKALVKTHNYSKAITYYEAAMKSGQQNYLCYDLAELLLKLKWYDKAEKVLQ
HALAHEP----------------VNELSALXXXXXXXXXXXXXXXXXXXXXXXXXXXXXA
RELQARVLKRVQIEQPDAVPAQKHLA

PF00515 // ENSGT00390000005979_0_Domain_11 (987, 1020)

AEICAEIAKHSVAQRDYEKAIKFYREALVHCETD
NKIMLELARLYLAQDDPDACLRHCALLLQSDQDN

PF00515 // ENSGT00390000005979_0_Domain_13 (1055, 1088)

EAATMMMADLMFRKQDYEQAVFHLQQ
LLERKPDNYMTLSRLIDFL-RRCGKLEDVPRFFLMAEKCNSRAKLEPGYQYCKGLYLWYT
GEPNDALRHFNKARKDSDWGQNSLYNMIEICLNPDNETVGGEVFENLDGDLGNSTEKQES
VQLAVRTAEKLLXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKDH
IPALLGMATAYMILKQTPRARNQLKRIAKMNWNPIDAEDF

PF00515 // ENSGT00390000005979_0_Domain_15 (1301, 1334)

ERSWLLLADIYIQSAKYDMA
EELLKRCLRHNRS

ENSGT00390000005979_0_Linker_15_16 (1334, 1370)

CCKAYEYMGYIMEKEQAYTDAALNYEMAWKHGNQTN

PF00515 // ENSGT00390000005979_0_Domain_16 (1370, 1415)

PSVGYKLAFN-
-YLKAKRY---------VDAIDVCHQ-VLEAHPTYPKIRKDILDKARTSLRP

------------------------------------------------------------
--VSESSSSLSQALLNYYCQECYFH-HVRAAAEEALGRL-GSDPVFHFYRAYGALRTGDI
QEGIRQLESIKNRQEVSLCAMMALIYAHKKSPNP---DRDAILELDTKLKEQRKTAGQQA
LYFAGLFLWHLGREDKAREYVDRVIKVSS-GDKEGLILKAWLDLTCGKETHIKKAVKYFD
EALQEGNDVFALLGKTQYFEIRQNYSGALETVNQIIANFPNFLPAFIKKMKLQLALQDWE
QAIETAHRLLQKDALNLEATRMEALHFLCREGNIREVSLVGCGQASTRLSDLLKALDRLE
PSNSQLLYKMALAFSRTCGRNQLILQHTQTLVERAFNLDSDN

PF07719 // ENSGT00390000005979_0_Domain_3 (403, 436)

AEFATELGYQMILQGKVK
EALKWYKTAMKLDETSVSALTGIIRCQLIQGQLEDAEQQLEFLNEIQQSIGKSGELSFLR
VVLAMKKQKRQEEVIALLNDVLDTHFSSLHGFPLGVEYFEKLNPDFLLEIIREYLSFCPA
QPASPGQSPSPLLKHCASVLETVVKTVPGLQQAVFLIAKVKYLS---GDI-EAAHTNLHY
CLERDPSYADAHLLMAQVYLAQNNTKLCSQSLELCLSYNFEVREH

PF00515 // ENSGT00390000005979_0_Domain_7 (646, 672)

PVYHLIKAQTLKKMG
ELSEAIKTLQM

ENSGT00390000005979_0_Linker_7_8 (672, 738)

ARNLPGMRKHTASSKAKGKRIEVDTSDRVAV-FLELVEAHCLNGEPHEA
AVVLQDAIDEFSGTPEE

PF07721 // ENSGT00390000005979_0_Domain_8 (738, 763)

LRVMIANADLAIAQGDVEQALTVLR

ENSGT00390000005979_0_Linker_8_9 (763, 809)

NITPEQPYFVQAKLKMAD
IYLQCRRDKKLYAACYRDL---VEKLPS

PF07719 // ENSGT00390000005979_0_Domain_9 (809, 842)

AHTFLLLGDAYMNIQEPDEAVEVYEQALKKNP
KDPALASKIGKALIKTHNYSKAISYYEAALKSGQQSFLCYDLAELLMKLKQYEKAEVALQ
QALDHEY----------------VNELSSLMED

PF00515 // ENSGT00390000005979_0_Domain_10 (934, 967)

GRYQVLLAKIYSKMEKIDEAIASLQQA
RELQAR

ENSGT00390000005979_0_Linker_10_11 (967, 987)

VLKRAQTEQPDAVPAQKQLA

PF07719 // ENSGT00390000005979_0_Domain_11 (987, 1020)

AEICAEIAKHCTVQRNYEKAIKFYKEALVHCETD
KKAMLELARLYLAQDDNDACQHQCSLLLRNEQDN

PF07719 // ENSGT00390000005979_0_Domain_13 (1055, 1088)

EAATMMMADLMFRKQDYEQAVFHFQQ
LLERKPD

ENSGT00390000005979_0_Linker_13_14 (1088, 1127)

NYATLSRLIDLL-RRAGKLEEVPRFLLMAEKYSSRAKLE

PF00515 // ENSGT00390000005979_0_Domain_14 (1127, 1153)

PGFHYCKGLYLWYT
GEPNDALRHFNK

ENSGT00390000005979_0_Linker_14_15 (1153, 1301)

ARKDNDWGQNAVYNMIEICLNPDNETIGGEVFENLDADIGNSTEKQES
VQLAVRTAENLLKELKPQTIQGHIQLRIMENYCLMATKQKSNVERALNTFTEIVVAEKDH
IPALLGMATAYMILKQTPRARNHLKRISKMNWNPIDAEEF

PF00515 // ENSGT00390000005979_0_Domain_15 (1301, 1334)

EKSWLLLADIYIQSSKYDTA
GELLKRCLRHNKS

ENSGT00390000005979_0_Linker_15_16 (1334, 1370)

CCKAYEYMGYIMEKEQAYKDAAINYEMAWRYGNQSN

PF00515 // ENSGT00390000005979_0_Domain_16 (1370, 1415)

PTIGYKLAFN-
-YLKGKRY---------VDAITICHK-VLEAHPNYPKIRKEILDKARASLRT

------------------------------------------------------------
-----MEAHVLKTLINYYCQERYFH-HVVTVASEGLKRY-VSDPVFRFYHAYGLLMEGRN
QEAFRELEAIKNKQDVSLCSLIALIYGHKLSSNP---DRETILELDAKMKEHRKTAGPKA
LYYAGLFLWHVGRHDKAREYVDRMIKISN-GSKEGLILRAWLDVTSGKEAYSKKAARYFD
ENIQDGNDIFAMLGKAQYLELRQNYSGALETVNQITINFPSFLPALVKKMKLQLALQDWD
QTVETAQRIIQQDSQNVESLRMLALYHLCREGNIQEA--------TSKLGDLITTLDAME
PQNAQLFYKMALAFSRTCGRNQLILQKTQMLVERAFGLTPQDAEFATELGYQMILKGKVK
EALKWYKTAMTLDETSVPALIGIIRCQLIEGQLQDADHQLEFLNEIQQTIGKSAELTYLY
AVLAMKKHKGQEEVINLLNDVLDIHFSNLQALPLGVQYFERLNPDFLLEIITEYLNFCPT
QPASPGQPPSPLLRHCASVLETIVRTVPGLLQAVFLIAKVKYLS---GDI-EASYSNLQH
CLEHDPSYADAHLLMAQVYLSQDNFKLCSQSLELCLSYSFEVREYPLYHLIKAQSQKKMG
QIAEAVKTLHMAMSLPGMRRIGASK-SKSQTSEIDASHRLSI-FLELVDAHRLNGEQHEA
AKVLQDAINEFSGTPEEL

PF07721 // ENSGT00390000005979_0_Domain_8 (739, 762)

RVTIANADLALAQGEVERALSML

ENSGT00390000005979_0_Linker_8_9 (762, 814)

RNVTPEQPYFVETKEKMAD
IYLKHRKEKKLYASCYRDL---VEKLPNPHTFL

PF00515 // ENSGT00390000005979_0_Domain_9 (814, 842)

LLGDAYMNIQEPEEAIEAYEQALKQNP
KDGTLASKIGKALVKTHNYSKAITYYEAALKSGQQNFLCYDLAELLLKLKRYEKAEKVLQ
HALAHEP----------------VNELSALIEDGRYQVLLAKIYSKMEKPGEAVIALQQA
RELQARVLKRVQMEQPDAVPTQKQLAAEICAEIAKHSAAQRDYEKSIKFYKEALVYCETD
NK

PF07721 // ENSGT00390000005979_0_Domain_12 (1023, 1043)

AMLELARLYLAQDDPDACQRHCALLLKNDQDNEAATMMMADLMFRKQDYEQAVFHFQQ
LLERKPDNYTTLSRLIDLL-RRAGKLEDVPRFLLMAEKHNARAKFEPGFQYCRGLYLWYT
GEPNDALRHFNKARKDSDWGQNAIYNMIEICLNPDNETVGGEVFENLDGDLGNSTEKQES
VQLAVRTAEKLLKELKPQTVQGHIQLRIMENYCLMATKQKANVERALNTFTEIATSEKDH
IPALLGMATAFMILKQTPRARNQLKRISKMNWNPIDAEEFEKSWLLLADIYIQSAKYDMA
GDLLRRCLRHNRSCCKAYEYMGYIMEKEQAYKDASVNYEMAWKYGNQTNPTVGYKLAFN-
-YLKGKRY---------VDAIDICHK-VLEAHPTYPKIRKDILDKARSSLRA

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------LILQDNQNVDALRILVLYYLCREGDIEKA--------ATKLENLVNALDNME
PQNAQLFYTITLAFSRTCGRSQVILQKIQSLLERAFGLNPEQPEFAIELGYQMILQGNIK
ESMKWYKIAIALDETSIPAITGYIHCQLLEGQLQEAAQQLEFLSEVQQSLGKSVELIFLD
VILAIKNNKGQEEVTNLFSDTLDTHFSHLEDVPLGVEYFEKLNPDFLLEIITEYLNFCPK
QPASPGQPLSPFLRRCTSVLETIVRTAPGL

PF00515 // ENSGT00390000005979_0_Domain_4 (571, 608)

LQAVFLLAKVKYLS---GDT-EAAYNNLQH
CLEHNSTYADAHLLMAQVFLSQEKFKLCSQSLELCLSYNFKVRECPLYHLIKAQSQKKVG
EVTEAIKTLHMAMSLPEMRRTGVPSKSKCRKTETDISHRLSV-FLELAELHHLNGEQHEA
AKVLQDAIHEFSGTSEELRVTIANADLTLAQGDVERALNMLRNVNAQQPYFTEAKEKMAD
IYLKHRKEKMLYITCYREI---AEKIPG

PF07719 // ENSGT00390000005979_0_Domain_9 (809, 842)

PRSLLLLGDAYMNIQEPEEAIVAYEQALSQNP
KDEILAIKIGKAFVKTHNYAKAITYYEAALKSGQQNYLCYDLAELLLKLKYFDKAEQVLQ
HILSHEP----------------VNELSALIED

PF00515 // ENSGT00390000005979_0_Domain_10 (934, 967)

GRSQVLLAKVYSKMERPGDAITSLQQA
REIQAR

ENSGT00390000005979_0_Linker_10_11 (967, 987)

VLKRVQMEQPDAVPAQKHLA

PF07719 // ENSGT00390000005979_0_Domain_11 (987, 1020)

AEICAEIAKHSVAQRDYEKAIKFYREALVHCETD
NKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX

PF07719 // ENSGT00390000005979_0_Domain_13 (1055, 1088)

XXXXXMMADIMFRKQDYEQAVFHLQQ
LLERKPDNYMTLSRLIDFL-RRCGKLEDVPRFFLMAEKHNSRAKLEPGFQYCKGLYLWYT
GEPNDALRHFNKARKDSDWGQNALYNMIEICLNPDNEPIGGEVFENLDGDLGNSTEKQES
VQLAVRTAEKLLKELKPQTVEGHVQLRIMENXXXXXXXXXXXXXXXXXXXXXXXXXXKDH
IPALLGMATAYMLLKQNPRARNQLKRIAKMNWNPIDAEDF

PF07719 // ENSGT00390000005979_0_Domain_15 (1301, 1334)

EKSWLLLADIYIQSGKYDMA
EELLKRCLRHNRS

ENSGT00390000005979_0_Linker_15_16 (1334, 1370)

CCKAYEYMGYIMEKEQAYTDAALNYEMAWKHGNQTN

PF00515 // ENSGT00390000005979_0_Domain_16 (1370, 1415)

PAVGYKLAFN-
-YLKAKRF---------VDAIDICHQ-VLEAHPTYPKIRKDILDKARTSLRS

------------------------------------------------------------
-----MDSQELKTLINYYCQERYFH-HVLLVASEGIKRY-GSDPVFRFYHAYGTLMEGKT
QEALREFEAIKNKQDVSLCSLIALIYAHKMSPNP---DREAILESDARVKEQRKGAGEKA
LYHAGLFLWHIGRHDKAREYIDRMIKMSD-GSKQGHVLKAWLDITRGKDPYTKKALKYFE
EGLQDGNDTFALLGKAQCLEMRQNYSGALETVNQIIVNFPSFLPSFVKKMKLQLALQDWD
QTVETAQWLLLQDSQNVEALRMQALYYVCREGDIEKA--------STKLENLGNALDDME
PQNAQLFYNITLAFSRTCGRSQLILQKIQTLLEKAFSLSPQQSEFATELGYQMILQGRVK
EALKWYKTAMTLDETSVSALVGFIQCQLIEGQLQDADQQLEFLNEIQQSIGKSAELIYLH
AVLAMKKNKQQEEVINLLNDVLDTHFSQIEGLPLGIQYFEKLNPDFLLEIVTEYLSFCPM
QPASPGQPLCPLLRRCVSVLETVVRTVPGLLQTVFLIAKVKYLS---GDI-EAAFNNLQH
CLEHNPSYADAHLLLAQVYLSQEKVKLCSQSLELCLSYDFKVREYPLYHLIKAQSQKKMG
EIADAIKTLHMAMSLPGMKRIGASIKSKDRKTEVDTSHRLSI-FLELIELHRLNGEQHEA
AKVLQDAIHEFSGTSEEVRVAIANADLALAQGDIERALSILQNVTAEQPYFIEAREKMAN
IYLKHRKDKMLYITCFREI---AERMANPRSFLLLGDAYMNILEPEEAIVAYEQALNQNP
KDGTLASKMGKALIKTHNYSMAITYYETALKSGQKNY

PF13181 // ENSGT00390000005979_0_Domain_9 (878, 903)

LCYDLAELLLKLKWYDKAEKVLQ
HALAHEP----------------VNELSALMEDGRCQVLLAKVYSKMERPGDAITALQQA
RELQARVLKRVQMEQPDAVPAQKHLAAEICAEIAKHS

PF14559 // ENSGT00390000005979_0_Domain_12 (998, 1064)

VAQRDYEKAIKFYREALVHYETD
NKIMLELARLYLAQDDPDSCLRQCALLLQSDQDNEAATMMMADLMFRKQDYEQAVFHLQQ
LLERKPDNYMTLSRLIDLL-RRCGKLEDVPRFFSMAEKRNSRAKLEPGFQYCKGLYLWYT
GEPNDALRHFNKARKDRDWGQNALYNMIEICLNPDNETIGGEVFENLDGDLGNSTEKQES
VQLAVRTAEKLLKELKPQTVQGHVQLRIMENYCLMATKQKSNVEQALNTFTEIAASEKDH
IPALLGMATAYMILKQTPRARNQLKRIAKMNWNAIDAEEFE

PF13181 // ENSGT00390000005979_0_Domain_15 (1302, 1329)

KSWLLLADIYIQSAKYDMA
EELLKRCLRHNRSCCKAYEYMGYIMEKEQAYTDAALNYEMAWKYSNRTNPAVGYKLAFN-
-YLKAKRY---------VDSIDICHQ-VLEAHPTYPKIRKDILDKARASLRP

------------------------------------------------------------
-----MDSQGLKTLINYYCQERYYH-HVLLVASEGMKKY-GSDPVFRFYHAYGTLMEGKS
QEALREFEAIKNKQDVSLCSLIALMYVHKMSPNP---DREAILELDTKMKEQRKEAGRKA
LYHAGLFLWHIGRHDKAREYIDRMSKMPH-DSNEGPILKAWLDITRGKEPYAKKALRYFE
EGLQDGNDIFALLGKVLCLEMRQNYSGALETVSQIIVNFPSFLPAFEKKMKLQLALQDWD
QTVETAQRLLLQDTHNVEALRMLALYYLCREGDIEKA--------AAKLDNLGNALDVME
PQNAQLFYKITIAFSRTCGRNQLILQKVQGFLEKAFSLTPQQAEIATELGYQMILQGKVK
EAWKWYRTAMTLNESNISAVTGLIRCQLIEGQLQDADQQLEFFSEFQQSMGKSAELMYLH
AVLATKKNTGQEEVVNLLNDVVNTHFSHLEDLPLGIQYFEKLNPDFLLEVVTEYLNFCPI
QPAGPGQPLSPVLRHCSSVLETIIRSVPGLPQAVFLMAKVKYLS---GDT-EAAYNNLQH
CLEHSPSYAEAHLLMAQVYLSQEKVKLCSQSLELCLSYNFNVRDYPLYHLIKAQSQKKMG
EIAEAIKTLHMAMNLPGMRRSRASSKSK-HRTEVDASHRLSI-FLELVEVHRLNGEQHEA
AKVLQDAIHEFSGTCEELRVTIANADLALAQGDTERALGMLRNVTTEQPYFIEAKEKMAD
IYLKHRKEKMLYITCYREI---AERMPSP

PF07719 // ENSGT00390000005979_0_Domain_9 (810, 842)

RAFLLLGDAYMNIQEPEEAIVAYEQALNQNP
KDGTLARKIGKALIKTHNYSKAITYYEAALKSGQQNCLCYDLAELLLRLKLYEKAEKVLQ
HSLSHEP----------------VNELSALMEDGRSQVLLAKVYSKMERPSDAIAALQQA
RELQARILKRVQMEQPDAVPSQKHFAAEICAEIAKHSAAQRDYEKAITFYKEALVHCETD
SKIMLELAQLYLAQEDLDASLRHCALLLQKDRDNEPATMLMADLMFRKQDYEQAVFHLQQ
LLERKPDNFMTLSRLIDLL-RRCGKLEDVPRFFSMAEKHNSRTKLEPGYQYCKGLHFWYT
GEPNDALRHFNKARKDSDWGQNALYNMIEICLNPDNETIGGEVFENLDGDLGSSTEKQES
VQLAVRTAEKLLKELKPQTVQGRLQLRVMENCCLMATKQKSSVEQALSTFTEIAASEKDH
IPALLGMATAYMILKQTPKARNQLKRIAKMSWNPIEAEDLE

PF13181 // ENSGT00390000005979_0_Domain_15 (1302, 1328)

KSWLLLADIYIQSAKYDMA
EELLKRCLCHNRSCCKAYEYMGYIMEKEQAYTDAAFNYEMAWKHSNQTNPSVGYKLAFN-
-YLKAKRY---------VDAIDICHQ-VLEAHPAYPKIRKDILDKARASLRP

------------------------------------------------------------
----------------------------------------------------------KT
QEALREFEAIKNKEDVSLCSQIALIYAHKMSPNPXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXX---XXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXAQCLEMSQIYSGALETVNKIIMNFPSFLPAYVKKMKLQLALQDWD
QTVETAQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----XXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXX-XXXXX-XXXXXXXXX-XXXXXXXXXX-XXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXELIYLY
AVLAMKKKKRQEEVINLLNDVLDTHFSHLADLPLGIQYFEKLNPDFLLEIVTEYLNFCPM
QPASPGQPLSPLLRRCISILETVVRTVPGL

PF00515 // ENSGT00390000005979_0_Domain_4 (571, 608)

LQAVFLIAKVKYLS---GDT-EAAYNNLQH
CLEHNPSYADAHLLMAQVFLCQEKFKLCSQSLELSLSYNFKXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXHEA
AKVLQDAIHEFSGTSEELRVTVANADLALSHGDVERALSMLQSVTAEQPYFTEAKEKMAD
IYLKYRKEKMLYIACYREV---AERLPSPRSFLLLGDAYMNIQEPEEAIVAYEQALNQNP
KD

PF00515 // ENSGT00390000005979_0_Domain_9 (843, 876)

ETLASKIGKALVKTHNYSKAITYYEAALKSGQQNYLSYDLAELLLKLKWYDKAEKVLQ
HSLAHDP----------------VNVLSSLVAD

PF00515 // ENSGT00390000005979_0_Domain_10 (934, 967)

ARSQVLLAKIYSKMERPSDAISSLQQA
RELQAR

ENSGT00390000005979_0_Linker_10_11 (967, 987)

VLKRVQMEQPDAVPTQKRLA

PF07719 // ENSGT00390000005979_0_Domain_11 (987, 1020)

AEICAEIAKHSVAQRDYEKAIKFYREALVYCERD
NKIMLELARLYLAQDDPDSRLRHCALLLQSDQDN

PF00515 // ENSGT00390000005979_0_Domain_13 (1055, 1088)

EAATMMMADLMFRKQDYEQAVFHLQQ
LLERKPDNYMTLSRLIDFL-RRCGKLDDVPRYFLMAEKCNSRAKLEAGFQYCKGLYLWYI
GEPNDALRHFNKARKDSEWGQNALYNMIEICLNPDNETIGGEVFENLDGDLGNTSEKQES
VQLAVRTADKLFK-LKPQTLQGHVQHRIMGNYCLMATKQKSNVEHALNTFTEIATLEKDH
IPALLGMATAYMILKQTPRARNQLKRIAKMNWNPVDAEDF

PF00515 // ENSGT00390000005979_0_Domain_15 (1301, 1334)

EKSWLLLADIYIQSAKYDMA
EELLKRCLRHNKS

ENSGT00390000005979_0_Linker_15_16 (1334, 1370)

CCKAYEYMGYIMEKEQAYTDAALNYELAWKHGNQTS

PF00515 // ENSGT00390000005979_0_Domain_16 (1370, 1415)

PAVGYKLAFN-
-YLKAKRY---------VEAIDICHQ-VLEAHPTYPKIRKDILDKARTSLRP

------------------------------------------------------------
-----MDSQELKTLINYYCQERYFH-HVLLVASEGIKRY-GSDPVFRFYHAYGTLMEGKT
QEALREFEAIKNKQDVSLCSLIALIYAHKMSPNP---DREAILESDARVKEQRKGAGEKA
LYHAGLFLWHIGRHDKAREYIDRMIKMSD-GSKQGHVLKAWLDITRGKDPYTKKALKYFE
EGLQDGNDTFALLGKAQCLEMRQNYSGALETVNQIIVNFPSFLPAFVKKMKLQLALQDWD
QTVETAQRLLLQDSQNVEALRMQALYYVCREGDIEKA--------STKLENLGNALDAME
PQNAQLFYNITLAFSRTCGRSQLILQKIQMLLERAFSLNPQQSEFAAELGYQMILQGRIK
EALKWYKTAMTLDETSVSALVGFIQCQLIEGQLQDADQQLEFLNEIQQSIGKSAELIYLH
AVLAMKKNKRQEEVINLLNDVLDTHFSQIEGLPLGIQYFEKLNPDFLLEIVMEYLSFCPM
QPASPGQPLCPLLRRCVSVLETVVRTVPGLLQTVFLIAKVKYLS---GDI-EAAFNNLQH
CLEHNPSYADAHLLLAQVYLSQEKVKLCSQSLELCLSYDFKVREYPLYHLIKAQSQKQMG
EIADAIKTLHMATSLPGMKRIGASTKSKDRKTEVDTSHRLSI-FLELIELHRLNGEQHEA
AKVLQDAIHEFSGTSEEVRVTIANADLALAQGDIERALSILQNVTAEQPYFIEAREKMAD
IYLKHRKDKMLYITCFREI---AERMANP

PF13181 // ENSGT00390000005979_0_Domain_9 (810, 842)

RSFLLLGDAYMNILEPEEAIVAYEQALNQNP
KDGTLASKMGKALIKTHNYSMAITYYETALKSGQKNYLCYDLAELLLKLKWYDKAEKVLQ
HALAHEP----------------VNELSALMEDGRCQVLLAKVYSKMERPGDAITALQQA
RELQARVLKRVQMEQPDAVPAQKHLAAEICAKIAKHS

PF14559 // ENSGT00390000005979_0_Domain_12 (998, 1064)

VAQRDYEKAIKFYREALVHCETD
NKIMLELARLYLAQDDPDSCLRQCALLLQSDQDNEAATMMMADLMFRKQDYEQAVFHLQQ
LLERKPDNYMTLSRLIDLL-RRCGKLEDVPRFFSMAEKRNSRAKLEPGFQYCKGLYLWYT
GEPNDALRHFNKARKDRDWGQNALYNMIEICLNPDNETIGGEVFENLDGDLGNSTEKQES
VQLAVRTAEKLLKELKPQTVQGHVQLRIMENYCLMATKQKSNVEQALNTFTEIAASEKDH
IPALLGMATAYMILKQTPRARNQLKRIAKMNWNAIDAEEFE

PF13181 // ENSGT00390000005979_0_Domain_15 (1302, 1329)

KSWLLLADIYIQSAKYDMA
EELLKRCLRHNRSCCKAYEYMGYIMEKEQAYTDAALNYEMAWKYSNRTNPAVGYKLAFN-
-YLKAKRY---------VDSIDICHQ-VLEAHPTYPKIRKDILDKAHASLRP

------------------------------------------------------------
-----MDSQELKTLINYYCQERYFH-HVLLVASEGIKRY-GSDPVFRFYHAYGTLMEGKT
QEALREFEAIKNKQDVSLCSLIALIYAHKMSPNP---DREAILESDARVKEQRKGAGEKA
LYHAGLFLWHIGRHDKAREYIDRMIKMSD-GSKQGHVLKAWLDITRGKDPYTKKALKYFE
EGLQDGNDTFALLGKAQCLEMRQNYSGALETVNQIIVNFPSFLPSFVKKMKLQLALQDWD
QTVETAQWLLLQDSQNVEALRMQALYYVCREGDIEKA--------STKLENLGNALDAME
PQNAQLFYNITLAFSRTCGRSQLILQKIQTLLEKAFSLNPQQSEFATELGYQMILQGRVK
EALKWYKTAMTLDETSVSALVGFIQCQLIEGQLQDADQQLEFLNEIQQSIGKSAELIYLH
AVLAMKKNKRQEEVINLLNDVLDTHFSQIEGLPLGIQYFEKLNPDFLLEIVTEYLSFCPM
QPASPGQPLCPLLRRCVSVLETVVRTVPGLLQTVFLIAKVKYLS---GDI-EAAFNNLQH
CLEHNPSYADAHLLLAQVYLSQEKVKLCSQSLELCLSYDFKVREYPLYHLIKAQSQKKMG
EIADAIKTLHMAMSLPGMKRIGASTKSKDRKTEVDTSHRLSI-FLELIELHRLNGEQHEA
AKVLQDAIHEFSGTSEEVRVAIANADLALAQGDIERALSILQNVTAEQPYFIEAREKMAN
IYLKHRKDKMLYITCFREI---AERMANP

PF13181 // ENSGT00390000005979_0_Domain_9 (810, 842)

RSFLLLGDAYMNILEPEEAIVAYEQALNQNP
KDGTLASKMGKALIKTHNYSMAITYYETALKSGQKNYLCYDLAELLLKLKWYDKAEKVLQ
HALAHEP----------------VNELSALMEDGRCQVLLAKVYSKMERPGDAITALQQA
RELQARVLKRVQMEQPDAVPAQKHLAAEICAEIAKHS

PF14559 // ENSGT00390000005979_0_Domain_12 (998, 1064)

VAQRDYEKAIKFYREALVHYETD
NKIMLELARLYLAQDDPDSCLRQCALLLQSDQDNEAATMMMADLMFRKQDYEQAVFHLQQ
LLERKPDNYMTLSRLIDLL-RRCGKLEDVPRFFSMAEKRNSRAKLEPGFQYCKGLYLWYT
GEPNDALRHFNKARKDRDWGQNALYNMIEICLNPDNETIGGEVFENLDGDLGNSTEKQES
VQLAVRTAEKLLKELKPQTVQGHVQLRIMENYCLMATKQKSNVEQALNTFTEIAASEKDH
IPALLGMATAYMILKQTPRARNQLKRIAKMNWNAIDAEEFE

PF13181 // ENSGT00390000005979_0_Domain_15 (1302, 1329)

KSWLLLADIYIQSAKYDMA
EELLKRCLRHNRSCCKAYEYMGYIMEKEQAYTDAALNYEMAWKYSNRTNPAVGYKLAFN-
-YLKAKRY---------VDSIDICHQ-VLEAHPTYPKIRKDILDKARASLRP

------------------------------------------------------------
-----MDSQGLKTLIDYYCQERYFH-HVVLFASEGIKMY-GNDPVFRLYHAYGTLMEGKT
QEALREFETTKNKQDVSLCSHIALIHTHKMSLHP---DKEAILELDSRMKELRKGAGQKA
LYYAGLFLWHIGRHDKARDYIDRMIKMSN-NSKEGLVLRGWLDITRGKEPYTKKALRYFE
EGLQDGNDIFALLGKAQCLEMRQKYSSALETVNQIIVNFPSFLPAFIKKMKLQLALQDWD
LTVETAQRLLIQDSQNVDALRMLALYYLCREGDIEKA--------TSKLENLGNALDTME
PLNAHLFYKITIAFSRTCGRSQPILQKTQTLLERAFRLNPQQSKFAAELGYQMILQGKVK
EASKWYKTAITLDETSVPALTGCIRCQLIEGELEDADQQLEFLSEIQQSIEKSAELTYLH
AVLAMKKNKRQEEVIDLLNDVLDTHLSHLEDLPLGIQYFEKLNPDFLLEIITEYLNFCPM
QPASPGQPLSPLLRRFTSVLETIVRTVPGLLQAVFLIAKVKYLS---GDI-EAAYNNLQR
CLEHSPSYADAHLLMAQVYLSQEKYKLCSQSLELCLSYDFKVREYPLYHLIKAQSQKKMG
EIAEAIKTLHMAMSLPGMRRTGASSESKYRKTEVETSHRLSV-FLELVDVHRLNGEQHEA
AKVLQDAIHEFSGTSEELRVTIANADLALVQGDVERALSMLRNVTVEQPYFIEVKEKMAD
IYLKHRKEKMLYITCYREI---AERMPNPRSF

PF07719 // ENSGT00390000005979_0_Domain_9 (813, 842)

LLLGDAYMNIQEPEEAIIAYEQALNQNP
KDGTLASKIGKALVKTHNYSKAITYYEAALKSGQQNYLCYDLAELLLKLKWYDKAEKVLR
HSLTHEP----------------VNELSALMEDGRSQVLLAKVYSKMNRPADAIASLQQA
RELQARVLKRVQMEQPDAVPAQKQLAAEICAEIAKHSVVQQDYEKAIKFYREALVHCETD
NKIMLELARLYLLQDDPDACLRHCALLLQSDQDNEAATMMMADLMFRKQDYEQAAFHLQQ
LLERKPDNYMTLFRLIDIL-RRCGKLEDVPRFFLMAEKHNSRAKLEPGYQYCKGLYLWYT
GEPNDALRNFNKARKDSDWGQNALYNMIEICLNPDNETIGGEVFENLDEDLGNSTEKQEC
MQLAVRTAEKLLKELKPQTAQGQVQLHIMENYCLMATKQKSNVEQALNVFTEIATSEKDH
IPALLGMATAFMILKQTPKARNQLKRIAKMNWNPIDAEEFEKSWLLLADIYIQSAKYDMA
EELLKRCLRHNKSCCKAYEYMGYIMEKEQAYTDAAFNYEMAWKHGSQTNPSVGYKLAFN-
-YLKAKRY---------VDAIDICHQ-ISS----------------------

------------------------------------------------------------
-----MDSQELKTLINYYCQERYFH-HVLLVASEGIKRY-GSDPVFRFYHAYGTLMEGKT
QEALREFEAIKNKQDVSLCSLIALIYAHKMSPNP---DREAILESDARVKEQRKGAGEKA
LYHAGLFLWHIGRHDKAREYIDRMIKMSD-GSKQGHVLKAWLDITRGKDPYTKKALKYFE
EGLQDGNDTFALLGKAQCLEMRQNYSGALETVNQIIVNFPSFLPAFVKKMKLQLALQDWD
QTVETAQRLLLQDSQNVEALRMQALYYVCREGDIEKA--------STKLENLGNALDAME
PQNAQLFYNITLAFSRTCGRSQLILQKIQTLLERAFSLNPQQSEFATELGYQMILQGRVK
EALKWYKTAMTLDETSVSALVGFIQCQLIEGQLQDADQQLEFLNEIQQSIGKSAELIYLH
AVLAMKKNKRQEEVINLLNDVLDTHFSQIEGLPLGIQYFEKLNPDFLLEIVTEYLSFCPM
QPASPGQPLCPLLRRCVSVLETVVRTVPGLLQTVFLIAKVKYLS---GDI-EAAFNNLQH
CLEHNPSYADAHLLLAQVYLSQEKVKLCSQSLELCLSYDFKVREYPLYHLIKAQSQKKMG
EIADAIKTLHMAMSLPGMKRIGASTKSKDRKTEVDTSHRLSI-FLELIELHRLNGEQHEA
AKVLQDAIHEFSGTSEEVRVTIANADLALAQGDIERALSILQNVTAEQPYFIEAREKMAD
IYLKHRKDKMLYITCFREI---AERMANP

PF13181 // ENSGT00390000005979_0_Domain_9 (810, 842)

RSFLLLGDAYMNILEPEEAIVAYEQALNQNP
KDGTLASKMGKALIKTHNYSMAITYYETALKSGQKNYLCYDLAELLLKLKWYDKAEKVLQ
HALAHEP----------------VNELSALMEDGRCQVLLAKVYSKMERPGDAITALQQA
RELQARVLKRVQMEQPDAVPAQKHLAAEICAEIAKHS

PF14559 // ENSGT00390000005979_0_Domain_12 (998, 1064)

VAQRDYEKAIKFYREALVHCETD
NKIMLELARLYLAQDDPDSCLRQCALLLQSDQDNEAATMMMADLMFRKQDYEQAVFHLQQ
LLERKPDNYMTLSRLIDLL-RRCGKLEDVPRFFSMAEKRNSRAKLEPGFQYCKGLYLWYT
GEPNDALRHFNKARKDRDWGQNALYNMIEICLNPDNETIGGEVFENLDGDLGNSTEKQES
VQLAVRTAEKLLKELKPQTVQGHVQLRIMENYCLMATKQKSNVEQALNTFTEIAASEKDH
IPALLGMATAYMILKQTPRARNQLKRIAKMNWNAIDAEEFE

PF13181 // ENSGT00390000005979_0_Domain_15 (1302, 1329)

KSWLLLADIYIQSAKYDMA
EELLKRCLRHNRSCCKAYEYMGYIMEKEQAYTDAALNYEMAWKYSNRTNPAVGYKLAFN-
-YLKAKRY---------VDSIDICHQ-VLEAHPTYPKIRKDILDKARASLRP

------------------------------------------------------------
-----MDSQELKTLINYYCQERYFH-HVLLVASEGIKRY-GSDPVFRFYHAYGTLMEGKT
QEALREFEAIKNKQDVSLCSLIALIYAHKMSPNP---DREAILESDARVKEQRKGAGEKA
LYHAGLFLWHIGRHDKAREYIDRMIKMSD-GSKQGHILKAWLDITRGKDPYTKKALKYFE
EGLQDGNDTFALLGKAQCLEMRQNYSGALETVNQIIVNFPSFLPAFVKKMKLQLALQDWD
QMVETAQRLLLQDSQNVEALRMQALYYVCREGDIEKA--------STKLQNLGNALDAME
PQNAQLFYNITLAFSRTCGRSQLILQKIQTLLERAFSLNPQQSEFATELGYQMILQGRIK
EALKWYKTAMTLDETSVSALVGFIQCQLIEGQLQDADQQLEFLNEIQQSIGKSAELIYLH
AVLAMKKNKRQEEVINLLNDVLDTHFSQIEGLPLGIQYFEKLNPDFLLEIVMEYLSFCPM
QPASPGQPLCPLLRRCVSVLETVVRTVPGLLQTVFLIAKVKYLS---GDI-EAAFNNLQH
CLEHNPSYADAHLLLAQVYLSQEKVKLCSQSLELCLSYDFKVREYPLYHLIKAQSQKKMG
EIADAIKTLHMAMSLPGMKRIGASTKSKDRKTEVDTSHRLSI-FLELIELHRLNGEQHEA
AKVLQDAIHEFSGTSEEVRVTIANADLALAQGDIERALSILQNVTAEQPYFIEAREKMAD
IYLKHRKDKMLYITCFREM---AERMANPRSFLLLGDAYMNILEPEEAIVAYEQALNQNP
KDGTLASKMGKALI

PF14559 // ENSGT00390000005979_0_Domain_9 (855, 931)

KTHNYSMAITYYETALKSGQKNYLCYDLAELLLKLKWYDKAEKVLQ
RALAHEP----------------VNELSALMEDGHCQVLLAKVYSKMERPGDAITALQQA
RELQARVLKRVQMEQPDAVPAQKHLAAEICAKIAKHS

PF14559 // ENSGT00390000005979_0_Domain_12 (998, 1064)

VAQRDYEKAIKFYREALVHCETD
NKIMLELARLYLAQDDPDSCLRQCALLLQSDQDNEAATMMMADLMFRKQDYEQAVFHLQQ
LLERKPDNYMTLSRLIDLL-RRCGKLEDVPRFFSMAEKRNSRAKLEPGFQYCKGLYLWYT
GEPNDALRHFNKARKDRDWGQNALYNMIEICLNPDNETIGGEVFENLDGDLGNSTEKQES
VQLAVRTAEKLLKELKPQTVQGHVQLRIMENYCLMATKQKSNVEQALNTFTEIAASEKDH
IPALLGMATAYMILKQTPRARNQLKRIAKMNWNAIDAEEFE

PF13181 // ENSGT00390000005979_0_Domain_15 (1302, 1329)

KSWLLLADIYIQSAKYDMA
EELLKRCLRHNRSCCKAYEYMGYIMEKEQAYTDAALNYEMAWKYSNRTNPAVGYKLAFN-
-YLKAKRY---------VDSIDICHQ-VLEAHPTYPKIRKDILDKARASLRP

------------------------------------------------------------
------------ALINYYCQERYFH-HVLMVASEGIKRY-GSDPVFRFYHAYGTLMEGKI
QEALREFEAIKNKQDVSLCSLIALIYAHKMSPNP---DREAILESDARVKEQRKGAGQKA
LYHAGLFLWHIGRHDKAREYIDRMIKMSN-GSKEGQVLRAWLDITRGKEPYTKKALRYFE
EGLQDGID

PF00515 // ENSGT00390000005979_0_Domain_1 (249, 282)

IFALLGKAQCLHMRQNYSGALEAVNQIIVSFPSFLPAFVKKMKLQLALQDWD
QTVETAQRLMLQDNKNVEALRMLALYYLCREGDIEKA--------TAKLENLGNALEAVE
PQNAHLFYKITIAFSRTCGRNQLILQKIQTLLEKAFSLSPHLSEFATELGYQMILQGKVK
EALTWYKTAMTLDETSVSALIGFIRCQLMEGQLQEADQQLEFLSEIQQSIGKSAELTYLH
AVLAMKKNKRQEEVIGLLNDALDTHFSHLEDLPLGIQYFETLNPDFLLEIITKYLNFCPV
QPLSPGQPLSPFLRRCASVLETIVRSVPGLLQAVFLIAKVKYLS---GDI-EAAYNNLQH
CLEHNSSY

PF00515 // ENSGT00390000005979_0_Domain_6 (609, 642)

ADAHLLMAQVYLSQEKFRLCSQSLELCLSHNFKVREYPLYHLVKAQSQKKMG
EIAEAVKTLHMAMSLPGMRRIGASSKSKSRKTEIDASHRLSI-FLELVEVHRLNGEQHEA
AKVLQDAIHEFSGTSEE

PF07721 // ENSGT00390000005979_0_Domain_8 (738, 763)

LRVTIANADLALAQGDVERALSMLRNVTSEQPYFIEAKEKMAD
IYLKYRKEKMLYITCYREV---AERMPCPRSFLLLGDAYMNIQEPEEAIVAYEQALNQNP
KD

PF00515 // ENSGT00390000005979_0_Domain_9 (843, 876)

GTLASKIGKALVKTHNYSKAITYYEAALKSGQQNYLCYDLAELLLKLKWYDKAEKVLQ
HALAHEP----------------VSELSALMED

PF00515 // ENSGT00390000005979_0_Domain_10 (934, 967)

GRSQVLLAKVYSKMERPGDAVASLQQA
RELQAR

ENSGT00390000005979_0_Linker_10_11 (967, 987)

VLKRVQMEQPDAVPAQKHLA

PF07719 // ENSGT00390000005979_0_Domain_11 (987, 1020)

AEICAEIAKHSVAQRDYEKAIKFYKEALVHCETD
NKIMLELARLYLAQDDPDACLRHCALLIQSDQDN

PF00515 // ENSGT00390000005979_0_Domain_13 (1055, 1088)

EAATMMMADLMFRKQDYEQAVFHLQQ
LLERKPD

ENSGT00390000005979_0_Linker_13_14 (1088, 1127)

NYMTLSRLIDLL-RRCGKLEDVPRFFLMAEKRNSRAKFE

PF00515 // ENSGT00390000005979_0_Domain_14 (1127, 1153)

PGFHYCKGLYLWYT
GEPNDALRHFNK

ENSGT00390000005979_0_Linker_14_15 (1153, 1301)

ARKDSDWGQNALYNMIEICLNPDNETVGGEVFENLDGDLGSSTEKQES
VQLAVRTAEKLLKELKPQTVQGHVQFRILENYCLVATKQKSNVEQALNTFTEIATSEKDH
IPALLGMATAYMILKQTPRARNQLKRIAKMSWNPIDAEEF

PF00515 // ENSGT00390000005979_0_Domain_15 (1301, 1334)

EKSWLLLADIYIQSAKYDMA
EELLKRCLRHNRS

ENSGT00390000005979_0_Linker_15_16 (1334, 1370)

CCKAYEYMGYIMEKEQAYSDAALNYEMAWKHGNQTN

PF00515 // ENSGT00390000005979_0_Domain_16 (1370, 1415)

PAVGYKLAFN-
-YLKGKKY---------VDAIDVCHQ-VLEAHPTYPKIRKDILDKARASLRP

------------------------------------------------------------
-----MDSQELKTLINYYCQERYFH-HVLLVASEGIKRY-GSDPVFRFYHAYGTLMEGKT
QEALREFEAIKNKQDVSLCSLIALIYAHKMSPNP---DREAILESDARVKEQRKGAGEKA
LYHAGLFLWHIGRHDKAREYIDRMIKMSD-GSKQGHVLKAWLDITRGKDPYTKKALKYFE
EGLQDGNDTFALLGKAQCLEMRQNYSGALETVNQIIVNFPSFLPAFVKKMKLQLALQDWD
QTVETAQRLLLQDSQNVEALRMQALYYVCREGDIEKA--------STKLENLGNALDAME
PQNAQLFYNITLAFSRTCGRSQLILQKIQTLLERAFSLNPQQSEFATELGYQMILQGRVK
EALKWYKTAMTLDETSVSALVGFIQCQLIEGQLQDADQQLEFLNEIQQSIGKSAELIYLH
AVLAMKKNKRQEEVINLLNDVLDTHFSQIEGLPLGIQYFEKLNPDFLLEIVTEYLSFCPI
QPASPGQPLCPLLRRCVSVLETVVRTVPGLLQTVFLIAKVKYLS---GDI-EAAFNNLQH
CLEHNPSYADAHLLLAQVYLSQEKVKLCSQSLELCLSYDFKVREYPLYHLIKAQSQKKMG
EIADAIKTLHMAMSLPGMKRIGASTKSKDRNTEVDTSHRLSI-FLELIELHRLNGEQHEA
AKVLQDAIHEFSGTSEEVRVTIANADLALAQGDIERALSILQNVTAEQPYFIEAREKMAD
IYLKHRKDKMLYITCFREI---AERMANPRSFLLLGDAYMNILEPEEAIVAYEQALNQNP
KDGTLASKMGKALIKTHNYSMAITYYETALKSGQKNY

PF13181 // ENSGT00390000005979_0_Domain_9 (878, 903)

LCYDLAELLLKLKWYDKAEKVLQ
HALAHEP----------------VNELSALMEDGRCQVLLAKVYSKMERPGDAITALQQA
RELQARVLKRVQMEQPDAVPAQKHLAAEICAEIAKHS

PF14559 // ENSGT00390000005979_0_Domain_12 (998, 1064)

VAQRDYEKAIKFYREALVHCETD
IKIMLELARLYLAQDDPDSCLRQCALLLQSDQDNEAATMMMADLMFRKQDYEQAVFHLQQ
LLERKPDNYMTLSRLIDLL-RRCGKLEDVPRFFSMAEKRNSRAKLEPGFQYCKGLYLWYT
GEPNDALRHFNKARKDRDWGQNALYNMIEICLNPDNETIGGEVFENLDGDLGNSTEKQES
VQLAVRTAEKLLKELKPQTVEGHVQLRIMENYCLMATKQKSNVEQALNTFTEIAAS-EDH
IPALLGMATAYMILKQTPRARNQLKRIAKMNWNAIDAEEFEKSWLLLADIYIQSAKYDMA
EEQLKRWLRHNRSCCKAYEYMGYIMEKEQAYTDAALNYEMAWKYSNRTNPAVGYKLAFN-
-YLKAKRY---------VDSIDICHQ-VLEAHPTYPKIRKDILDKARASLRP

------------------------------------------------MAAR-------P
-RPAPPLPPLPEALVGFGPGLRDSE-PLAPPLGRGGRKFRRLAPPPGESHGF-AGAEGRT
QEALREFEAIKNKQDVSLCSLIALIYAHKMSPNP---DKEAILESDARVKEQRKGAGPKA
LYHAGLFLWHIGRHDKAREYIDRMIKMSN-GSKEGQVLRAWLDITRGKEPYTKKALRYFE
EGLQDGNDIFALLGKAQCLEMRQNYSGALDTVNQIIVNFPSFLPAFVKKMKLQLALQDWD
QTVETAQRLMLQDNQNVEALRILALYYLCREGDIEKA--------ATKLENLENALDATE
PQNAQLFYKITVAFSRTCGRSQLILRKIQTLLQRALALNPEQSEFATELGYQMILQGDMK
EALKWYNTAMKLDETSVPALIGVIRCQLIEGQLQDADQQLEFLSEIQQSIGKSAELIYLH
AILAMKKNKRQEEVINMLNDVLDTHFSHLEDLPLGIQYFENLNPDFLLEIITEYLNFCPM
QPASLGQPLSPLLRRCTSILETIVRTVPGLLQAVFLIAKVKYLS---GDI-EAAYNYLQH
CLEHNPSYADAHLLIAQVYLSQEKFKLCSQSLELCLSYNFKVRECPLYHLIKAQSQKKMG
EIAEAIKTLHMAMSLPGMRRIGASSKSKHRKTEVDANHRLSI-FLELVEAHRLNGEQHEA
AKVIQDAIHEFSGTSEELRVTIANADLALAQGDVERALSMLRNVTAEQPYFIEAKEKMAD
IYLKHRKEKMLYITCYREI---AERMPSPRSFLLLGDAYMNIQEPEEAIIAYEQALNQNP
KDGTLASKIGKALVKT

PF14559 // ENSGT00390000005979_0_Domain_9 (857, 931)

HNYSKAITYYEAALKSGQQNYLCYDLAELLLKLKWYDKAEKVLQ
HALAHEP----------------VNELSALMEDGRSHVLLAKVYSEVERPGDAIASLQQA
RELQSRILKRVQMEQPDAASAQKHLAAEICAGIAKHS

PF14559 // ENSGT00390000005979_0_Domain_12 (998, 1064)

VAQRDYEKAIKFYREALVHCETD
NKILLELARLYLAQDDPDACLRHCALLLQSDQDNEAATMMMADLMFRKQDYEQAVFHLQQ
LLERKPDNYMTLSRLIDFL-RRCGKLEDVPRFFLMAEKRNSRAKLEPGFQYCKGLYLWYT
GEPNDALRHFNKARKDSDWGQNALYNMIEICLNPDNETVGGEVFENLDGDLGNSTEKQES
VQLAVRTAEKLLKELKPQTIQGHVQLRIMENYCLVATKQKSNVEQALNTFTEIATSERDH
IPALLGMATAYMILKQTPRARNQLKRIAKMNWNPIDAEDFE

PF13181 // ENSGT00390000005979_0_Domain_15 (1302, 1329)

KSWLLLADIYIQSAKYDMA
EELLKRCLRHNRSCCKAYEYMGYIMEKEQAYTDAALNYEMAWKHGNQTNPTVGYKLAFN-
-YLKAKRY---------VDAIDVCHQ-VLEGHPTYPKIRKDILDKARMSLRP

------------------------------------------------------------
-----PVAACSQALLNYYCQERLFQ-HVRAAADEALARL-GVDPVLLFYRAYGALRAGDV
QESIRQLESIKNKPEVSLCTMMALIYAHKKSPNP---DRDAILELDARLKEQRKTAGQQA
LYYAGLFLWHLGREDKAREYADRMIKVSG-GSKEGLILKAWLDLTCGKETHIKKALKYFD
EALQEGNDVFALLGKAQYFEVRQKYSGALEIVNQIIANFPNFIPAFIKKMKLQLALQDWE
QTIETAHRLLQKDPLNLEAIRMEALHHLCRGGNTSEA--------SARLGDLIKALDRLE
PRNSDLFCKMALAFSRTCGRNQLILQHTQTLVQRAFDLASDNAEFATELGYQMILQGKVN
EAQKWYKTAMTLDETSVSALTGIIHCQLIQGQLEDAEHQLEFLNEIQQSIGKSGELSFLH
AVLAMKKHKRQEDVFALLNDVLDTHFSSLHGFPLGVEYFEKLNPDFLLEIIREYLNFCPS
QPASPGQSPSPLLKHCASVLETVVKTVPGLQQAVFLIAKVKYLS---GDI-EAAHRNLHY
CLERNPSYADAHLLMAQVYLAQNNIKLCSQSLELCLSHNFEVREHPVYHLIKAQTQKKVG
EIAEAIKTLQMARNLPGMRKPTASSKTKGKSIEIDASDRVSV-FLELVEAHRLNGEPHEA
AIVIQDAMNEFSGTPEEIRVVIANADLAIAQGDVKHALTMLRNITLEQPYFVQAKEKMAD
IYLQYRKDKKLYVACYSDL---VEKLPSAHT

PF00515 // ENSGT00390000005979_0_Domain_9 (812, 842)

LLLLGDAYMNIQEPDEAIEVYEQALKKNP
KDPSLASKIGKALIKTHNYSKAISYYEAAVRSGQQNFLCYDLAELLMKLKQYEQAEKVLQ
QALDHEP----------------VNELSSLMEDVRYQVLLAKIYSKMETIDRAIVSLQQA
RELQGRVLKRAQVEQLDAVPAQKQLAAEICAEIAKHSTAQRNYEKAIKFYKEALVHCETN
NKAMLELARLYLAQDDTDAGQHQCSLLLKNDQDNEAATMMMADLMFRKQDYEQAIFYFQQ
LLERKPDNYATLSRLIDLL-RRAGKLEEVPRFLSMAEKHSSRTKLEPGFHYCKGLYLWYT
GEPNDALRHFNKARKDSDWGQNAVYNMIEICLNPDNETVGGEVFENLDADIGNSTEKQES
VQLAVRTAGNLLKELKPQTIQGHIQLRIMENYCLMATKQKSSVEQALNTFTEIVVSEKDH
IPALLGMATAYMILKQTPRARNQLKRISKMSWNPIDAEDFEKSWLLLADIYIQSAKYDMA
GELLKRCLRYNRSCCKAYEYMGYIMEKEQAYKDAAMNYEMAWKYGNQTNPTVGYRLAFN-
-YLKGKRY---------VDAIDVCHK-VLKVHPNYPKIRKEILDKAHACLR-

------------------------------------------------------------
------------ALINYYCQERYFH-HVVLFASEGIMRY-SNDPVFRY-HAYXXXXXXXX
XXXXXXXXXXXXXXX---XXXXXXXXXXXXXXXXXXXXKEAILELDSKMKELRKGAGQKA
LYYAGLFLWHIGRHDKARDYIDRMIKMSN-SSKEGLILRGWLDITRGKEPYTKKALRYFE
EGLQDGYD

PF00515 // ENSGT00390000005979_0_Domain_1 (249, 282)

IFALLGKAQCLEMRQNYSGALETVNQIIVNSPSFLPAFIKKMKLQLALQDWD
LTVETAQRLLVQDNQNVDALRMLALYYLCREGDIEKA--------ASKLESLGNALESME
PQNAQLFYRITIAFSRTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXCIRCQLIEGELEDADQQLEFLNEIQQSIEKSAELTYLH
AVLAMKKNKQEEEVMNLLNDVLDTHLSHLEDLPLGIQYFEKLNPDFLLEIITEYLSFCPM
QPASPGQPVSPLLRRCTSILETIVRTVPGLLQAVFLIAKVKYFS---GDI-EAAHSNLQH
CLEHSPSYADAHLLMAQVYLSQEKFKLCSQSLELCLSYDFK-------------------
----------------GRRRTSASSESKYRKTEVDTSHRLSV-FLELVEVHRLNGEQXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXX----XXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXX--------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXIMLELARLYLLQDDPEACLRHCALLLQSDQDN

PF07719 // ENSGT00390000005979_0_Domain_13 (1055, 1088)

EAATMMMADLMFRKQDYEQAAFHLQQ
LLERKPDNYMTLSRLIYIL-RRCGKLEDVPRFFLMAEKHNSRAKLEPGYQYCKGLYLWYT
GEPNDALRNFNKARKDSDWGQNALYNMVEICLNPDNETIGGEVFENLDENLGNSTEKQEC
MQLAVRTAEKLLKELKPQTIQGHVQLHIMENYCLMATKQKANVEQALNAFTEIATSEXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXSCCKAYEYMGYIMEKEQAYTDAAFNYEMAWKHSSQTN

PF00515 // ENSGT00390000005979_0_Domain_16 (1370, 1415)

PAVGYKLAFN-
-YLKAKRY---------VDAIDICHQ-VLEAHPTYPKIRKDILDKARMSLRP

------------------------------------------------------------
--QIIQGFKLISTLINYYCQERYFH-HVLLVASEGMKRY-GSDPVFRFYHAYGTLMEGKI
QEALREFEAITNKQDVSLCSLIALIYAHKMSPNP---DREAILESDARVKEQRKGADQKA
LYHAGLFLWHVGRHDKAREYIERMIKMPN-SSNEGQILKAWLDITRGKEPYAKKALRCFE
EGLQDGKDIFALLGKAQCLEMRQNYSSALETVNQIIVNFPSFLPAFIKKMKLQLALQDWD
QMVETAQRLLLQDNQNVEALRMLALYSLCREGNIDKA--------ANKLENLENALDIVE
PQNPELFYKIT-----KCGRSQLILQKVQALLEKAFSLTPQSSEFAAEIGYQMILQGKVK
EALTWYQTAMTLDNTSISALIGFIRCQLMDGQFQEADQQLEFLSEVQQSMEKSADLIYLH
AVLAMKKNKQEEEVVCLLNDVLDTHFSHLEELPLGIQYFETLNPDFLLEVITEYLNFRPI
----PGQPLAPFLRRCMWVLEIIVRTVPGLLQAFFLLAKVKYLS---GNT-EAAFSNLQH
CLDHSPAYADAHLLMAQVYLSQEKFKLCSQSLELCLSYNFNVREYPLYHLIKAQSQKKMG
EITEAIKTLHMAMNLPGMRRTGVSSKSKYRKTEVDMGHRSSI-FLELVDVHRLNGEQHEA
AKVLQDAICEFSGTSEELRVTIANADLALAQGDVERALSVLRNVTAEQPYFIEAKEKIAD
IYLKHRKEKILYITCYREI---AERMPSPRSFLLLGDAYMNIQEPEEAIEAYEQALNLNP
KDGTLASKIGKALVKT

PF14559 // ENSGT00390000005979_0_Domain_9 (857, 931)

HNYSKAITYYEAALKSGQQNYLCYDLAELLLKLKLYEKAEKVLQ
HALAHEP----------------VNELSALMEDTRSQVLLAKVYSEMVRAGDAVTSLQQA
RELQARVLKRVQMEQPDAVPAQKHLAAEICAEIAKHS

PF14559 // ENSGT00390000005979_0_Domain_12 (998, 1063)

VAQQDYEKAIMFYREALVHCETD
NKIMLELARLYLAQGDTDACLRHCMMLLQSDQDNEAATMMMADIMFRKQDYEQAVFHLQQ
LLERKPDNYMTLSRLIDLL-RRCGKFDDVPRLFVMAEKRNSRAKVEPGFQYCKGLYLWYT
GEPNEALRHFNKARKDSEWGQNALYNMIEICLNPDNETIGGEVFENLEGDLGNSTEKQES
VQLAVRTAEKLLKELKPQTIQGHVQLRIMENYCLMATKQKPNVEQALNTFTEVAKSENDH
IPALLGMATAYMILKQTPKARNQLKRIAKMNWNPIDAEEFE

PF13181 // ENSGT00390000005979_0_Domain_15 (1302, 1329)

KSWLLLADIYIQSAKYDMA
EDLLRQCLRHNRSCCKAYEYMGYIMEKEQAYSDAASNYEMAWKYGNQTNPAVGYRLAFN-
-YLKAKRY---------VDAIDICHQ-VLEAHPTYPKIRKDILDKARASLRP