Query Results 

------------------------------------------------------------
MPEPRGSSPLRVNKAFAARYGRYREREELQRLKDRYGDPDS--GGDSSSESDSSDERVEF
DPQQERDF--YRTLSLLKKKDPRIYQKDATFYQRTESSS----SSESEQEAAAS----GK
QKKVLPMYLKDYERKVILEKGGKYVDEENSEGESSDGRRQ-----QTWSQTYVE------
--EQKQLQ---ESFRPFMED-SEDEDSAGEGGSGLLQKRR-KTREEKAQEDAEYVEWLKG
QKEIENPESLKEL------------MHLKEYWDNPELDAGEQFLRDYILNKRYKEVEG--
---------DEEEEEEEGVLGPPVQLAVDDSSDEGELFLKKQEAFEHKYNFRFEEPDSAS
VKTYPRSIASSVRRKDERRKEKREETR

PF05178 // ENSGT00390000005605_0_Domain_0 (448, 544)

ERKKREKA---RKREDLKQLKNLKRKEILAKLE
QLRQVTGNST--LGLEEQDLEGDFDPAQHEQLMQKCLGDDFYGAVEEEKPQFEEEDG---
-LE

ENSGT00390000005605_0_Linker_0_2 (544, 672)

EDWNWDTWAGPERD-GV------WS--QQEPHCEDPDFNMDADYDPSQPQ-------
---------KKQ---------------CEAPATGRKKRR--------SPFAAAVGQE---
--KPVFNPG-D

PF12936 // ENSGT00390000005605_0_Domain_2 (672, 763)

KTFEEYLDEYYRLDYEDIIDDLPCRFKYRRVVPCDFGLSTEEILAADDK
ELNRWCSLKKTC----MYRSEQEELQDQRAYSQKARNSRKKQQIFRSLGPEEMG---TAT
DAT--GEPQRHAAGPR-----------------------------E--------------
-QPQPEH--PL----------------AQE---EEAPVVPCKTP-VPSKRRR-GKKARLL
GPTVTLGGREFSRQRLQAFGLNPKRLHFRQLDRQRRKQQGPKSRP-------------

-------------------------------------------------------GHRAA
MPEPRGSSQLRVNAAFAARYNRYREREELQRLKDRYGDRDS--GGDSSSESDSSDERVEF
DPHQERDF--YRTLSLLKKKDPRIYQKDATFYQRTA------SSSDSEEEPAAS----EK
QKKVRPMYLKDYERKVILEKEGKYVDEENSDGETSNHRLQ-----RTSSQSYVE------
--EQKQLK---ESFRAFVED-SEDEDSAGEGGSGLLQKRA-KTRQEKAQEEADYIEWLKG
QKEIRNPESLKEL------------NHLKEYWNDPELDEGEQFLRDYILNKRYEEEED--
-------------EEEEGVPGPPVQLAVDDSSDEGELFLKKQEDFEHKYNFRFEEPDSAS
VKTYPRSIASSVRRKDERRKEKREETR

PF05178 // ENSGT00390000005605_0_Domain_0 (448, 548)

ERKKREKA---KKQEELKQLKNLKRKEILAKLE
KLRKVTGNET--LGLEERDLEDDFDPAQHDQLMEKCFGDEYYGAVEEEKPQFEEEE----
GLEDDWN

ENSGT00390000005605_0_Linker_0_2 (548, 672)

WDTWDGPEQD-GD------WS--QWELHCEDPDFNMDADYDPSQPR-------
---------KKK---------------HKAPLTGKKQRK--------SPFAAAVGQE---
--KPVFEPG-D

PF12936 // ENSGT00390000005605_0_Domain_2 (672, 763)

KTFEEYLDEYYRLDYEDIIDDLPCRFKYRTVVPCDFGLSTEEVG---PR
ELNRWLSLKKTACPLSACRSEQEELREQAAYSQKAQNSRKKQQIFKSLCREVSSAE-TPA
EAT--RKPQRDEAGPQ-----------------------------KQLPALDGAGG----
KRPWPEC--LP----------------AQE---EEAPMLPPEKL-ALQRRRR-AKKARLL
GPTVTLGGHEFSRQRLQAFGLNPKRLHFRQLGRQRRKQQGPKSSS-------------

--------------------------------MRAGPRAAPPRPGR--PQCACAMGHRAA
MPEPRGSSQLRVNTAFAARYNRYREREELQRLKDRYGDRDS--GSDSSSESDSSDERVEF
DPQQERDF--YKTLSLLKKKDPRIYQKDATFYNRTA------SSSDSEEEPAAS----EK
QKKVRPMYLKDYERKVILEKAGKYVDEENSDGETSNHRLQ-----ETSSQSYVE------
--EQKQLK---ESFRAFVED-SEDEDSAGEGGSSLLQKRA-KTRQEKAQEEADYIEWLKG
QKEIGNPESLKEL------------THLKEYWNDPELDEGERFLRDYILNKRYEEEEDEE
ED-E----E-EKEEEEEGVPGPPVQLAVDDSSDEGELFLKKQEDFEQKYNFRFEEPDSTS
VKTYPRSIASSVRRKDERRKEKREETR

PF05178 // ENSGT00390000005605_0_Domain_0 (448, 548)

ERKKREKA---KKQEELKQLKNLKRKEILAKLE
KLRKVTGNDT--LGLEEGDLEDDFDPAQHDQLMQKCFGDEYYGAVEEEKPQFEEEE----
GLEDDWN

ENSGT00390000005605_0_Linker_0_2 (548, 672)

WDTWDGPEQE-GD------WS--QQELHCEDPNFNMDADYDPSQPR-------
---------K-K---------------REAPSTGKKKRK--------SPFAAAVGQE---
--KPVFEPG-D

PF12936 // ENSGT00390000005605_0_Domain_2 (672, 763)

KTFEEYLDEYYRLDYEDIIDDLPCRFKYRTVVPCDFGLSTEEILAADDK
ELNRWCSLKKTC----MYRSEQEELRDKRAYSQKAQNSRKKRQVFKSLCREE--AE-MPA
EAT--GKPQRDGAGPQ-----------------------------RQLPGLDGAGG----
KRPRPES--PP----------------AQE---EEAPVSPHKKP-APQRRRR-AKKARLL
GPTVMLGGREFSRQRLQAFGLNPKRLYFRQLGRQRRKQQGPKNSS-------------

------------------------------------------------------VDRRAA
MPEPRGSSPLRVNAAFAARYGRYREREELQRLKDRYGDRDS--CGDSSSESDSGDERVEF
DTQQERDF--YRTLSLLKKKDPRIYQKDATFYQRTASS-----SDS-KEEPAAE----DK
QKKVQPMYLKDYERKVILEKGGKYIDEENSDGEASNQRLQ-----QTSLKSYVE------
--EQKQLK---ESFRAFVED-SEDEDSAGEGSSGLLQKRA-KSREEKAQEDADYIEWLKG
QKEIQNPDTLKEL------------THLKEYWNNPELDEGERFLRDYILNKRYEEEGDEE
EE-E-----E--EKKGEEVPGPPVQLAVDDSSDEGELFLKKQEDFEHKYNFRFEEPDSAS
VKTYPRNITSSVRQKDERRKERREETRERKRREKA---RKQEELKQLKNLKRKEILAKLE
RLRQVTGNET--LG

PF05178 // ENSGT00390000005605_0_Domain_1 (495, 767)

FEEQDLEDDFDPAQHDQLMQKCFGDKYYGTMEEEKPQFEEEEGL--
E--DDWNWDMWAGPEQS-GA------WS--QQEPHCEDPDFNMDADYDPSQPQ-------
---------KQQ---------------RKSPSLGKKKRK--------SPFAAAVEQE---
--KPVFDPG-DKTFEEYLDEYYQLDYEDIIDDLPCRFKYRTVVPCDFGLSTEEILTADDK
ELNRWCSLKKTC----MYRSEQEELQDRRAYSQKAQNVWKKRQIFKSLCPEETE--M-PT
EAT--GKPQRDKAGPQ-----------------------------GQLLAPDGLW-----
---EPES--PP----------------VQE---EAAPATTAEKP-APQRQKR-GKKARLL
GPTVTLGGCEFSRQRLQAFGLNPKRLHFRQLGRQRRKRQGPKSHP-------------

------------------------------------------------------MGHRAA
MPEPRGSSQLRVNAAFAARYNRYREREELQRLKDRYGDRDS--SSDSSSESDSSDERVEF
DPQQERDF--YKTLSLLKKKDPRIYQKDATFYNRTA------SSSDSEEDPEAL----EK
QKKVRPMYLKDYERKVILEKAGKYVDEENSDGETSNHRLQ-----ETSSQSYVE------
--EQKQLK---ESFRAFVED-SEDEDGAGEGGSSLLQKRA-KTRQEKAQEEADYIEWLKG
QKEIRNPDSLKEL------------THLKEYWNDPELDEGERFLRDYILNKRYEEEEE--
---E----E-E-MEEEEGVHGPPVQLAVDDSSDEGELFLKKQEDFEQKYNFRFEEPDSAS
VKTYPRSIASSVRRKDERRKEKREETR

PF05178 // ENSGT00390000005605_0_Domain_0 (448, 548)

ERKKREKA---KKQEELKQLKNLKRKEILAKLE
KLRKVTGNET--LGLEEGDLEDDFDPAQHDQLMQKCFGDEYYGAVEEEKPQFEEEE----
GLEDDWN

ENSGT00390000005605_0_Linker_0_2 (548, 672)

WDTWDGPEQE-GD------WS--QQELHCEDPNFNMDADYDPSQPR-------
---------KKK---------------REAPLTGKKKRK--------SPFAAAVGQE---
--KPVFEPG-D

PF12936 // ENSGT00390000005605_0_Domain_2 (672, 762)

KTFEEYLDEYYRLDYEDIIDDLPCRFKYRTVVPCDFGLSTEEIFAADDK
ELNRWCSLKKTC----MYRSEQEELRDKRAYSQKAQNSWKKQQVFKSLCREE--AE-TPA
EAT--GKPQTDEAGPQ-----------------------------RQLPALDGSLM----
G---LES--PP----------------AQE---EEAPVSPHKKP-APQKRRR-TKKARLL
GPTVMLGGCEFSRQRLQAFGLNPKRLHFRQLGRQRRKQQGPKNSS-------------

------------------------------------------------------------
MPEPRASGSLKVNAAFAARYSRYREREELQRLKDRYGDPDDG--GDSSSESDSSDEHVEF
DPQQERDF--YRTLSLLKKKDPRIYQKDATFYQRTAEAS----SSEGEEEPA-ALGKQ--
-EKLQPMYLKDYERKVILEKEGKYVDEDNSDGETVDHRLQ-----ETSTKSYVE------
--EQRQLK---ESFRAFVED-SSDEDSAGEGGSGLLQKHT-KSGEEKAQEEVDYLEWLKG
QKEVDSSESLKEL------------THLKEYWNNPELDEGEQFLRDYILNKRYEEEEEEE
-----------EEEEEEGAPGPPVQLTVDDSSDEGELFLKKQEDFEHKYNFRFEEPDSAS
VKTYPRSIASSVRRKDERRKEKREETR

PF05178 // ENSGT00390000005605_0_Domain_0 (448, 547)

ERKKREKA---RKQEELKQLKNLKRKEILAKLE
KLRQVTGNET--LGLEEQDLEDDFDPAQHDQLMQKCFGDAFYGTAEEEKPQFEEEDG---
-LEDDW

ENSGT00390000005605_0_Linker_0_2 (547, 672)

NWDMWSGPEQD-GA------WS--QRELHCEDPDFNMDADYDPSQPR-------
---------KKL---------------REAPTSGKRKRK--------SPFAAAVGQE---
--KPMFDPGD-

PF12936 // ENSGT00390000005605_0_Domain_2 (672, 762)

KTFEEYLDEYYRLDYEDIIDDLPCRFKYRTVVPCDFGLSTEEILSADDK
ELNRWCSLKKTC----MYRSEQEEMQEQRVYSQKARNTWKKRQIFKSLCQEEME---MPT
EAT--GKSQ-SKASPQ-----------------------------VQVPTPNGADQ----
KTPEAET--SV----------------SEE---EGLAHTSCSEKPASQ-KQK-SKKARLL
GPTVTLGGHKFSRQRLQAFGLNPKKLHFRQFGRQRKKQQSHS----------------

------------------------------------------------------------
----------------------------------------------------------EF
DPQQERDF--YTTLSLLKKKDPRIYQKDATFYQRTAESS---SSES-EEEPAAE----QK
QKKTRPMYLKDYERKVILEKEGKYVDEENSDGEPSHQRPQ------VTSKSYVD------
--EQKQLK---ESFRAFVED-SEDEDSAGEGGSGLLQKRA-KTREEKAQEDADYVEWLKG
QKEIPNPDALKEL------------THLKEYWNNPELDEGEQFLRDYILNKRYEEEEDEE
EV-E------EDEEEEEGIPGPPVQLAVDDSSDEGELFLKKQEDFEHKYNFRFEEPDSAL
VKTYPRSIASSVRRKDQRRKERREETRERKKKEKA---KKQEEIKQLKNLKRKEILAKLE
RLRQVTGNET--LG

PF05178 // ENSGT00390000005605_0_Domain_1 (495, 767)

FEEQDLEEDFDPARHDQLMQKCFGDEYYGAMEEEKPQFEEEEGL--
E--DDWNWDTWAGPEQG-TA------WS--QEELHCEDPDFNMDADYDPSQPR-------
---------RKQ---------------REAPSMGKKKRK--------SPFAAAVGQE---
--KPVFEPG-DKTFEEYLDEYYRLDYEDIIDDLPCRFKYRAVVPCDFGLSTEEILAADDK
ELNRWCSLKKTC----MYRSEQEELQDKRAYSQKAQNAWKKRQIFKSLCPEETE--M-PT
EAT--GKPPRDKAGPQ-----------------------------GQLPAPDGACG----
KQPRPGS--PP----------------AQE---EAAPGSSPEKP-APPRRKR-GKKARLL
GPTVTLGGHEFSRQRLQAFGLNPKRLHFRQLGRQRRKQKGPKSGP-------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------MYLKDYERKVILEKAGKYVDEENSDGETSNHRLQ-----ETSSQSYVE------
--EQKQLK---ESFRAFVED-SEDEDGAGEGGSSLLQKRA-KTRQEKAQEEADYIEWLKG
QKEIRNPDSLKEL------------THLKEYWNDPELDEGERFLRDYILNKRYEEEEEEE
ED-E----E-E-MEEEEGVHGPPVQLAVDDSSDEGELFLKKQEDFEQKYNFRFEEPDSAS
VKTYPRSITSSVRRKDERRKEKREETR

PF05178 // ENSGT00390000005605_0_Domain_0 (448, 548)

ERKKREKA---KKQEELKQLKNLKRKEILAKLE
KLRKVTGNET--LGLEEEDLEDDFDPAQHDRLMQKCFGDEYYGAVEEEKPQFEEEE----
GLEDDWN

ENSGT00390000005605_0_Linker_0_2 (548, 672)

WDTWDGPEQE-GD------WS--QQELHCEDPNFNMDADYDPSQPR-------
---------KKK---------------REAPLTGKKKRK--------SPFAAAVGQE---
--KPVFEPG-D

PF12936 // ENSGT00390000005605_0_Domain_2 (672, 762)

KTFEEYLDEYYRLDYEDIIDDLPCRFKYRTVVPCDFGLSTEEILAADDK
ELNRWCSLKKTC----MYRSEQEELRDKRAYSQKAQNSWKKRQVFKSLCREE--AE-TPA
EAT--GKPQRDEAGPQ-----------------------------RQLPALDGSLM----
G---PES--PP----------------AQE---EKAPVSPHKKP-APQKRRR-AKKARLL
GPTVMLGGCEFSRQRLQAFGLNPKRLHFRQLGRQRRKQQGPKNSS-------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
MSRC------APSVSPAPPRRAPPALSVADSSDEGELFLARQEDFERSYNFRFQEPGARQ
VQTYPRSIPTSVRRRDERRKEKRERVQ

PF05178 // ENSGT00390000005605_0_Domain_0 (448, 543)

ERKRKEKE---RKREELKQLKKLKREEISARLQ
RLRGVSGGGT--VGFSRSQLDGDFDPAQHDRMMAEVFGDEYYGCVEEEKPHFEEEEEEEE
GQ

ENSGT00390000005605_0_Linker_0_2 (543, 673)

EDNWNWDTWS--------------GR---AEPHCEDPDFVVRPVVPPPPSTHLGGTTA
P-PPPEPTPHRWT--------PTTTPPPPRPPPGAPTHRRWARSGAARASERRWSAT---
--NPHSTPA-AG

PF12936 // ENSGT00390000005605_0_Domain_2 (673, 761)

SFEQYLDEYYGLDYEDLVGDLPCRFKYRSVVPCDFGLTTDEILAADDK
ELNRWCSLRKTC----MYRSEREERQDQANYSRRAQNLWKKHQILKSLAVQAEEET----
--PPAPKSSKSKMGKK-------------------------------QR--DKQRHKVGS
PPPSP----MVV---------------AEDVTPTPTPPK-TPKMGSPKHKDQ-M--RHKE
------GSPPLPQPC---------K---------------------------------

------------------------------------------------------------
----------------------------------------------------------EF
DPQQERDF--YRTLSLLKKKDPRIYQEDATFYQRTATSS---ES---EEEL-AA----EK
QKKMRPMYLKDYERKVILEKEGKYVDEENSDGETSNQRLQ-----QVSSKSYVE------
--EQEQLK---ESFRAFVED-SEDEDSAGEGGSGLLQKRA-KTKEEKAQEDADYIEWLKG
QREIENPEALREL------------THLKEYWNNPELDEGEQFLRDYILNKRYEEEGDEE
EE-E------EEEEEEGRVPGPPVQLSIDDSSDEGELFLKKQEDFEHKYNFRFEEPDSAV
VKTYPRSIASSVRRKDERRKEKREEIRERKRREKA---KKQEELKQLKNLKRKEILAKLE
KLRQVTGNET--VG

PF05178 // ENSGT00390000005605_0_Domain_1 (495, 767)

FEEQDLEDDFDPTRHDQLMQKCFGDEYYGTMEEEKPQFEEEEGF--
E--DHWNWDTWTGLEQG-GD------WS--QQELHCEDPDFNMDADYDPSQPQ-------
---------KKQ---------------REAPLTGKKKRK--------SPFAAAVGQE---
--KPVFNPR-DKTFEEYLDEYYRLDYEDIIDDLPCRFKYRTVVPCDFGLSTEEILAADDK
ELNRWCSLKKTC----MYRSEQEELQDKKAYSQKAQNSWKKRQIFKSLCSEEKE--T-PT
EAT--GKPQRDKAGPQ-----------------------------GQLLASDGACR----
KQPQPES--PL----------------AQK---EAAPVSPTEKP-ALQRRRR-GKKARLL
GPTVTLGGQEFSRQRLQAFGLNPKRLHFRLLARKRRKQQGLKS---------------

------------------------------------------------------VGHRAA
MPEPHGSSQLRVNAAFAARYNRYREREELQRLKDRYGDRDS--GGDSSSESDSSDERVDF
DPQQERDF--YRTLSLLKKKDPRIYQKDATFYQRTA------SSSDSEEEPAAS----EK
QRKVRPMYLKDYERKVILEKEGKYVDEENSDGETSNHRLQ-----RTLSQSYVE------
--EQKQLK---ESFRAFVED-SEDEDSAGEGGSGLLQKRA-KTRQEKAQEEADYIEWLKG
QKEIRNPESLKEL------------THLKEYWNDPELDEGEQFLRDYILNKCYEEEEDE-
-------------EEEEGVPGPPVQLAVDDSSDEGELFLKKQEDFEHKYNFRFEEPDSAS
VKTYPRSIASSVRRKDERRKEKREETR

PF05178 // ENSGT00390000005605_0_Domain_0 (448, 536)

ERKKREKA---KKQEELRQLKNLKRKEILAKLE
KLRKVTGNET--LGLEERDLEDDFDPAQHDQLMEKCFGDEYYGAVEEEKPQFEEE

ENSGT00390000005605_0_Linker_0_2 (536, 673)

EGTRL
GLVDDWNWDTWDGSEQD-GD------WS--QRELHCEDPDFNVGLAGSDL-SE-------
---------DEK---------------ARGPLDGQEEAQ--------VTLRCSSGAGEAR
AVGGEGAPQ-DL

PF12936 // ENSGT00390000005605_0_Domain_2 (673, 762)

TFEEYLDEYYRLDYEDIIDDLPCRFKYRAVVPCDFGLSTEEILAADDK
ELNRWCSLKKTC----MYRSEQEELRDKRAYSQKAQNSWKKQQIFKSLCREE--TE-TPA
EAT--GKPQRDDAGPQ-----------------------------KQLPALDGAGG----
KRPQPES--LP----------------AQE---EEAPVLPPEKL-ALQRRRR-AKKARLL
GPTVTLGGCEFSRQRLQAFGLNPKRLHFRQLGRQQRKQQGPKSSS-------------

------------------------------------------------------MGRRAA
MPEPRGSSPLRVNAAFAARYSRYREREELQRLKDRYRDRGS--GDDSSSESDSSDERVEF
DPHQERDF--YRTLSLLKKKDPRIYQKDATFYQRTATSS---ESEG-E---LAA----EK
QKKARPMYLKDYERKVILEKEGKYVDEENSDGETSNQKLQ-----QVSSKSYVE------
--EQQQLK---ESFRAFVED-SEGEDSAGEGGSGLLQKRA-KTKEEKAQEDADYVEWLKG
QKEMQNVETLREL------------THLREYWNNPELDEGEQFLRDYILNKRYEEEEEE-
----------EEEEEEEGVAGLPVQVAVDDSSDEGELFLKKQEDFEHKYNFRFEEPDSAL
VKTYPRSIMSSVRRKDERRKERREETRERKRREKA---KKQEELKQLKNLKRKEILAKLE
KLRQVTGNKT--LG

PF05178 // ENSGT00390000005605_0_Domain_1 (495, 767)

FEERDLEDDFDPTRHDQLMQKCFGDEYYGTMEEEKPQFEEEEGL--
E--DDWNWDTWAGLQQG-GD------WS--QQELHCEDPDFNMDADYDPSQPR-------
---------KKQ---------------REPPSAGK-KRK--------SPFAAAVGQE---
--KPVFNPG-DKTFEEYLDEYYRLDYEDIIDDLPCRFKYRAVVPCDFGLSTEEILAADDK
ELNRWCSLKKTC----MYRSEQEELQDKRAYSRKAQNSWKKRQIFKSLCPEETD--T-PT
EAT--GKPQRDKAGPQ-----------------------------GQLLAPDGLW-----
---EPES--PP----------------AQE---EAAPVSSTEKPPVPQRRKR-GKKARLL
GPTVTLGGHEFSRQRLQAFGFNPKRLYFRLLGQQRRKQQGLKSGP-------------

------------------------------------------------------VDQRAA
MPEPRGSSPLRVNAAFAARYSRYREREELQRLKDRYGDRDS--GGDSSSESDSSDERVEF
DPQQERDF--YRTLSLLKKKDPRIYQENATFYQRTGIFGWPAAASSESEESAAV----EK
QKKVRPMYLKDYERKVILEKEGKYVDEENSDGEAFDQRHQ-----QTLSQSYVE------
--EQKQLK---ESFRMFVED-SEDEDSAGDGGSGLLQKRA-KTREEKAQEEADYVEWLKG
QKEVENPETLKEL------------THLKDYWNNPELDEGERFLRDYILNKRYKCKPEEQ
E-----------QREMQEPPGPVVQLAVDDSSDEGELFLKKQEDFEHKYNFRFEEPDSAV
VKTYPRSIVSSVRRKDERRKEKREETRERKRREKA---KKQEELKQLKNLKRKEIMAKLE
KLRQVTGNET--LG

PF05178 // ENSGT00390000005605_0_Domain_1 (495, 767)

LEEQDLEDDFDPARHDQLMQKCFGDEYYGTMEKEKPQFEEEEGL--
EGPDDWNWDTWNGPEQD-GA------WG--QQELHCEDPDFNMDADYDPSQPR-------
---------K-K---------------REAPSTGKKKRK--------SPFATAVGQE---
--KPVFDPG-DRTFEEYLDEYYRLDYEDIIDDLPCRFKYRTVVPCDFGLSTEEILAADDK
ELNRWCSLKKTC----MYRSEQEELQDQRAYSQKAQSSRKKGQIFKSLCSE---ME-IPT
EAT--GKPQRGKAGPQ-----------------------------QQLPAPDGAHG----
KRPQPES--PP----------------AQE---KVASMSAPEKP-APQKRRQ-GKKARLL
GPTVTLGGREFSRQRLQAFGLNPKRLHFRQLGRQQRKQREPK----------------

------------------------------------------------------MGHRTA
MPEPRGSSQLRVNTAFAARYNRYREREELQRR-----------------------ESGEF
DPQQERDF--YKTLSLLKKKDPRIYQKDATFYNRTA------SSSDSEEEPAAL----EK
QKKVRPMYLKDYERKVILEKAGKYVDEENSDGETSNHRLQ-----ETSSQSYVE------
--EQKQLK---ESFRAFVED-SEDEDSAGEGGSSLLQKRA-KTRQEKAQEEADYIEWLKG
QKEIRNPESLKEL------------THLKEYWNNPELDEGERFLRDYILNKGYEEEEDEE
----------EKEEEEEGVPGPPVQLAVDDSSDEGELFLKKQEDFEQKYNFRFEEPDSAS
VKTYPRSIASSVRRKDERRKEKREETR

PF05178 // ENSGT00390000005605_0_Domain_0 (448, 548)

ERKKREKA---KKQEELKQLKNLKRKEILAKLE
KLRKVTGNET--LGLEEGDLEDDFDPAQHDQLMQKCFGDEYYGAVEEEKPQFEEDE----
GLEDDWN

ENSGT00390000005605_0_Linker_0_2 (548, 672)

WDTWDGPEQE-GD------WS--QQELHCEDPNFNMDADYDPSQPR-------
---------K-K---------------REAPSTGKKKRK--------SPFAAAVGGS---
--LTLSRAG-D

PF12936 // ENSGT00390000005605_0_Domain_2 (672, 762)

KTFEEYLDEYYRLDYEDIIDDLPCRFKYRTVVPCDFGLSTEEILAADDK
ELNRWCSLKKTC----MYRSEQEELRDKRAYSQKAQNSWKKRQVFKSLCREE--AE-TPT
EAT--GRPQRDEAGPQ-----------------------------RQLPVLDGAGG----
KRPRPES--PP----------------AQE---EEAPVSLHKKP-APQRQRR-AKKARLL
GPTVMLGGREFSRQRLQAFGLNPKRLYFRQLGRQRRK-QGPKNSS-------------

------------------------------------------------------------
MPEPRGSSPLRVNAAFAARYGRYREREELQRLKDRYGDRDS--GDDSSSESDSSEERVEF
DPQQERDF--YRTLSLLKKKDPRIYQKDVTFYQRTASSS---SSES-EEEPAAS----EK
QKKVQPMYLKDYERKVILEKEGKYVDEENSDGETCNQ----------TAKSYVE------
--EQKQLK---ESFRVFMED-SEDEDSAGEGGSGLLQKHA-KTREEKAQEEADYVEWLKG
QKEIPNPESLKEL------------THLKEYWNDPELDEGEQFLRDYILNKRYEEEEEEE
E-----------EEEEEEGEGPRVQLAVEDSSDEGELFLKKQEDFEHKYNFRFEEPDSAS
VKTYPRTIASSVRRKDERRKEKREETR

PF05178 // ENSGT00390000005605_0_Domain_0 (448, 572)

ERKRREKA---RKQEELKQLKNLKRKEILAKLE
KLRQVTGNKT--LGLEEQDLEDDFDPTRHDQLMQKCFGDDFYGTAEEEKPQFEEEEGQ--
-------------------------------

ENSGT00390000005605_0_Linker_0_2 (572, 672)

QEPHCEDPDFNMDADYDPSQHR-------
---------KKQ---------------REIPSTGKKKRK--------SPFATAVGQE---
--KPVFNPGED

PF12936 // ENSGT00390000005605_0_Domain_2 (672, 762)

KTFEEYLDEYYRLDYEDIIDDLPCRFKYRTVVPCDFGLSTEEILAADDK
ELNRWCSLKKTC----MYRSEQEELQDKRAYSQKAQNSWKKRQIFKSLCPEETQTQM-ST
EST--RKPERDKASPQ-----------------------------GQLPVPDGACR----
NQPQAES--PP----------------AQE---EEVSVSPTEKP-APQRRKR-NKKARLL
GPTVTLGGHEFSRQRLQAFGLNPKRLHFRQLSKQLRKQRGPKSCP-------------

------------------------------------------------------SGLRAA
MPEPRGQCELRVNEAFAARYGRYRQREELQKLKDRYGDRGSGAESSSDSDSDSSDERVXX
XXXXXXXX--XXXXXXXXXXXXXX-XXXXXXXXXXXXXX-----XXXXXXXXXX----KK
KKKEKPMYLKDYERKVILEKEGXXXXXXXXXXXXXXXXXX-----X-XXXXXXXXX----
--XXXXXXXX----XXXXXX-XXXEESAGEGGSGLLRKR-TKTKAEKAQEEADYVDWLKG
QKDTKDKDDLKEL------------THLKEYWNNPQLDDGEKFLRDYILNRGYEEEEEEE
EGEE-----------ERGLPSAERQLKVEDSSDEGELFLRKQEDFERKYNFRFEEPDSSV
XXXXXXXIASSVRRKDERRKEKREATRERKKKEKL---KKQEELKQLKNLKRREILNKLE
KLREITGNKD--AG

PF05178 // ENSGT00390000005605_0_Domain_1 (495, 767)

FEEADLEGDFDPAMHDQLMQKCFGDEYYGIGEEEKPQFEEEEG---
-FDDEWNWDTWTGAEEN-GT------WR---QEPHCEDPDFNMDADYDPSQP--------
-------KKKKWD--------M--------PLPGKKRRK--------SHFAEVVSQE---
--RPVFDPE-DKTFEEYLDEYYRLDYEDIIDDLPCRFKYRSVVPCDFGLTTEEILASDDK
ELNRWCSLKKTC----MYRSEQEEMREQKQYSLKAKNVRKKQQILQSLGRK---------
------------------------------------------------------------
--------------------------------------------------------GRLL
GPRVKLGGFEFSHQRLQAYGLNAKRLHYRQLGRERRKQPGPRP---------------

------------------------------------------------------------
MPEPRGSSPLRVNAAFAARYGRYREREELQRLKDRYGDRHS--GSDSSSESDSSDEHVEF
DPQQERDF--YRTLSLLKKKDPRIYQKDATFYQRTVSS-----SDS-EEELAAE-----K
RKKVQPMYLKDYERKVILEKGGKYVDEENSDGETSDQRFQ-----QTSSKSYVE------
--EQKQLK---ESFRAFVED-SEDEDSAEEGGSGLLQKRA-KSREEKAQEDADYIEWLKG
Q-EIQNPDTLKEL------------THLREFWNNPELDEGERFLRDYILNKRYEEEGEEE
DE-E------EEDEEEERVPGPPVQLAVDDSSDEGELFLKKQEDFELKYNFRFEEPDSAS
VKTYPRSIASSVRRKDERRKEKREETR

PF05178 // ENSGT00390000005605_0_Domain_0 (448, 547)

ERKKREKA---RKQEELKQLKNLKRKEILAKLE
RLRQVTGNET--LGFEEQDLEDDFDPARHDQLMQKCFGDEYYGAMEEEKPQFEEEEGL--
E--DDW

ENSGT00390000005605_0_Linker_0_2 (547, 672)

NWDMWAGPEQG-GA------WS--QQEPHCEDPDFNMDADYDPSQPR-------
---------KKQ---------------REAPSLGKKKRK--------SPFAAAVGQE---
--KPVFDPG-D

PF12936 // ENSGT00390000005605_0_Domain_2 (672, 762)

KTFEEYLDEYYRLDYEDIIDDLPCRFKYRTVVPCDFGLSTEEILAADDK
ELNRWCSLKKTC----MYRSEQEELQDKRAYSQKARNVWKKRQIFKSLCPEEAE--M-PT
EAT--GKPQRDRAGSS-----------------------------GQLVALDGACG----
KRSRPES--TP----------------AEE---EADPVTPTEKL-GPQRRKR-GKKARLL
GPTVTLGGREFSRQRLQAFGLNPKRLHFRQLGRQRRKQQGPKASH-------------

------------------------------------------------------------
------MAELKINRKFAERYDRYREKEELQRLKDRYGDLPEEEEGTSS--SESEDEEMVI
DPKLDKEF--YRTLSLLKRKDPRIYQEDVTFYSNEESAS-----------------GQSK
AAKEKPMYLKDYERQVILEKEGKYEDEEDSEEDDDLQDQQ-----RARSPTYLE------
--EQKQIR---ESFRTFVED-SDNEDGEGTAG-NLLTRRI-KTKKEQEEEEEEYIAWLKG
QKEIHDKGEVKEM------------GFLKEYWSDPALDEGEKFLRDYILNKEYLEEKEDS
EE------------DEECPPALEEAPHVSDSEDEGELFLKKQEDFERKYNFRFEEPDSDL
VKTFPRTIAQSVRRKDDRRKTKREETKERKMKVGG---RKGRQ--RYRVQGEQEELGRLQ
KLRELAGEKS--LD

PF05178 // ENSGT00390000005605_0_Domain_1 (495, 767)

VTEDDLLEDFDPEKHDLIMQKCFGDDYYGVEEDQKPQYF-------
-PPDEWNWDSWTGEEAS-GW------GQ--EGETHCDDPEFVMDADYDPEAAPGPSRRER
K--------RLR---------------LEAQQSGKKRKK--------SKFAEVVSKE---
--KPVFDPG-DKTFQQYLDEYYQLDYEDIIDDLPCRFKYRQVVPCNFGLSTEEILAAEDK
ELNRWCSLRKTC----MYRSEKEEYQDQKAYGQKAQNQWKKLQVLKSLTQSDDAQETTPP
SKTKVGKKRRDRLKQREGAEQPREETAEATDMHCESDLPASSKDTADILAPSKAAAA---
RQQGPEVSLGPSKPDVAVSNVEQETLESQSAEGNHGHTEEKAGPPKSKRRKFGKKGGRLL
STKVRLGGREFSGQRLRAFGLNPKRLRYRQLGRERRKKVSRGQRKENSGRK-------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------MYLKDYERKVILEKEGKYVDEENSDGETSNHRLQ-----RTLSQSYVE------
--EQKQLK---ESFRAFVED-SEDDDSAGEGGSGLLQKRA-KTRQETAQEEADYIEWLKG
QKEIRNPESLKEL------------THLKEYWNDPELDEGEQFLRDYILNKRYEEEED--
-------------EEEEGVSGSPVQLVVDDSSDEGELFLKKQEDFEHKYNFRFEEPDSAS
VKTYPRSIASSVRRKDERRKEKREETR

PF05178 // ENSGT00390000005605_0_Domain_0 (448, 548)

ERKKREKA---KKREELKQLKNLKRKEILAKLE
KLRKVTGNET--LGLEERDLEDDFDPAQHDQLMEKCFGDEYYKAMEEEKPQFEEEE----
GLEDDWN

ENSGT00390000005605_0_Linker_0_2 (548, 673)

WDTWHGPEQD-GD------WS--QRELHCEDPDFNMDADYDPSQLR-------
---------KEK---------------HKAPLTGKKKRK--------SPFAAAVGQE---
--KPVFEPG-DR

PF12936 // ENSGT00390000005605_0_Domain_2 (673, 762)

TFEEYLDEYYRLDYEDIIDDLPCRFKYRTVVPCDFGLSTEEILAADDK
ELNRWCSLKKTC----MYRSEQEELRDKRAYSQKAQNSWKKQQIFKSLCQEE--TE-TPT
EAT--GKPQRDEAGPQ-----------------------------KQLAALDGAAR----
KWSWPES--LP----------------AQE---EEAPVLPPEKL-ALQRRRR-AKKARLL
GPTVTLGGREFSRQRLQAFGLNPKRLHFRQLGRQRRKQQGPKSSS-------------

-------------------------------------------------------VSRGA
MPEPRAPSPLRVNKAFAARYSRYREREELQRLKDRYGDPDS----DSSSESDSSDERVEF
DPQQERDF--YRTLSLLKKKDPRIYQQDVTFYQKTVSTS----ESEEEEKPATV----QS
RKKVRPMFLKDYERKVILEKEGKYVDEENSDGELQ----------QFSSQSYVE------
--EQKQLK---DSFRPFVED-SDEEDSAGEGGSSLLQKRA-KTREEKAHEDADYLNWLKG
QKETDGSG---------FLRPWKNFTHLREYWNNPELDEGERFLRDYILNKGYEEEEEEE
EE-E-------EEEEEEGVPGPPVQLAVQDSSDEGELFLRKQEDFEHKYNFRFEEPDSTS
VKTYPRSIASSVRRKDERRKERREETRERKKREKA---KKREELKQLKNLKRKEITAKLE
RLRQVTGNAS--LG

PF05178 // ENSGT00390000005605_0_Domain_1 (495, 767)

LDARDLEADFDPASHDQLMQKCFGDEYYGAAEEEKPQFEEEEG---
-LEDDWNWDAWAGPGE--------------QQEPHCEDPDFNMDADYDPSQPR-------
---------RKQ---------------RTAPETGKKKRK--------SPFAAAVEQD---
--KPLFQPG-DRSFEQYLDEYYRLDYEDIIDDLPCRFKYRTVVPCDFGLSTEEILAADDK
ELNRWCSLKKTC----MYRSEQEELKDKRAYMQKAQNSRKKQQIFKSLCREXXXXXXX--
-XX--XXXXXXXXXXX-----------------------------XQQPAPDGAGR----
KRPPPET--PP----------------VRE---D----------PTPQRRRK-AKKARLL
GPTVTLGGHEFSRQRLQAFGLNPKRLHFRQLGRRRKKQQQPANGP-------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
QKKARPMYLKDYERKVILEKEGKYVDEEHSDGESSNQRQQ-----QTWSRSYVE------
--EQEALK---ESFRTFVED-SEEEE-EEDGNSGLLQKRA-KTREEKAQEEADYVEWLKG
QKEIGNPETLHEL------------SHLKDYWNNPQLDEGERFLRDYILNKRYEEEGEED
QE-------DSEEEEEEGPPHPLGQLAVDDSSDEGELFLKKQEDFEHKYNFRFEEPDSAT
VRTYPRSISSSVRRKDERRKEKREETRERKRREKA---KKQQELKQLKNLKRKEILXXXX
XXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXX

PF05178 // ENSGT00390000005605_0_Domain_1 (514, 713)

XKYFGAEYYGAIEDEKPQFEEEEG---
-LEDDWNWDTWEGPGQD-DA------WA--QQELHCEDPDFNMDADYDPSQPR-------
---------KKK---------------RQAPSMGQKKRK--------TPFATAVGQE---
--KPVFEPG-DRTFGEYLDEYYRLDYEDIIDDVPCRFKYRAVVPCDFGLSTEE-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------

-------------------------------------------------------VGSAA
MPEPRGSSPLRVNAAFAARYSRYREREELQRLKDRYGDRER--GGDSSSESDSSEERVEF
DPQQDRDF--YRTLSLLKKKDPRIYQKDATFYQRTA------SSSDSEE-SAAT----EK
QKKVPPMYLKDYERKVILEKEGKYVDEENSDGEASHPRRQ-----QTLSQSYVE------
--EQKQL----TSFRTFVEN-SEDEDSAEENGAGLLQKCA-KTREEKAQEEADYVEWLKG
QKEVENPETLKEL------------THLRDYWNNPELDEGERFLRDYILNKRYEEEEEEE
ED-K----DEEEQEEGRGTPGPLARLAVDDSSDEGELFLKKQEDFEHKYNFRFEEPDSTV
VKTYPRSITSSVRRKDERRKEKREETRERKRREKA---KKQEELKQLKNLKRKEILAKLE
KLRQVTGNET--LG

PF05178 // ENSGT00390000005605_0_Domain_1 (495, 767)

LEEQDLEDDFDPARHDQLMQKCFGDEYYGTTEEEKPQFEEEE----
GLEDDWNWDRWDGPEQD-GA------WG--QQELHCEDPDFNMDADYDPSQPR-------
---------K-K---------------HEAPSMSKKKRK--------SPFATAVGQE---
--KPVFDPG-DRTFGDYLDEYYRLDYEDIIDDLPCRFKYRTVVPCDFGLSTEEILAADDK
ELNRWCSLKKTC----MYRSEQEELHDKRAYSQKAQNSWKKSQIFKSLCSEE--MD-MPT
EAT--GKPQSDKAGPR-----------------------------EQLPVPDGSPH----
-----ES--PL----------------AQE---EVAPESAPKKP-ATQKRRR-GKKARLL
GPTVTLGGRQS--HRLQAFGL--IRLHFRQLGQQQQRKPR------------------

MSAGCREPRGWGSGMGGGCSLPRRGVARGRGLRAPGPGCVAPPPGRRCFPDACAVGRRAA
MPEPRGSSPLRVNAAFAARYGRYREREELQRLKDRYGDRRS--GSDSSSESDSSDEHVEF
DPQQERDF--YRTLSLLKKKDPRIYQKDATFYQQTVSS-----SDS-EEELAAE-----K
RKKVQPMYLKDYERKVILEKGGKYVDEENSDGETSDQRFQ-----QTSSKSYVE------
--EQKQLK---ESFRAFVED-SEDEDSAEEGGSGLLQKRA-KSKEEKAQEDADYIEWLKG
Q-EIQNPDTLKEL------------THLREFWNNPELDEGERFLRDYILNKRYEEEGEEE
DE-E------EEDEEEERVPGPPVQLAVDDSSDEGELFLKKQEDFELKYNFRFEEPDSAS
VKTYPRSIASSVRRKDERRKEKREETRERKKREKA---RKQEELKQLKNLKRKEILAKLE
RLRQVTGNET--LG

PF05178 // ENSGT00390000005605_0_Domain_1 (495, 767)

FEEQDLEDDFDPARHDQLMQKCFGDEYYGTMEEEKPQFEEEEGL--
E--DDWNWDMWAGPEQG-GA------WS--QQEPHCEDPDFNMDADYDPSQPR-------
---------KKQ---------------REAPSLGKKKRK--------SPFAAAVGQE---
--KPVFDPG-DKTFEEYLDEYYRLDYEDIIDDLPCRFKYRTVVPCDFGLSTEEILAADDK
ELNRWCSLKKTC----MYRSEQEELQDKRAYSQKARNVWKKRQIFKSLCPEEAE--M-PT
EAT--GKPQRDRAGSS-----------------------------GQLVALDGACG----
KRSRPES--TP----------------AEE---EADPVTPTEKL-GPQRRKR-GKKARLL
GPTVTLGGREFSHQRLQAFGLNPKRLHFRQLGRQRRKQQGPKASH-------------

------------------------------------------------------------
MPEPRGSSPLRVNKAFAARYGRYREREELQRLKDRYGDPHG--GSDSSSESDSSDERVEF
DPQQERDF--YRTLSLLKKKDPRIYQKDATFYQRTGSPS----SSENEEESAAP----QK
RKKVQPMYLKDYERKVILEKGGKYVDEENSDGETSDQRVQ-----QTSSQSYVE------
--EQKQLR---DSFRPFVED-SEDEDSAGEGGSGLLQKRR-KTREEKDQEDADYVEWLKG
QKEIQNRKSLKEL------------MHLKEYWDNPELDEGEQFLRDYILNKRYEEEGSEE
EGDE----EEEEEEEEEGVPGPPVQVAVDDSSDEGELFLKKQEDFEHKYNFRFEEPDAAL
VKTYPRSIASSMRRRDERRKEKREETR

PF05178 // ENSGT00390000005605_0_Domain_0 (448, 544)

ERKKREKA---RKQEELKQLKNLKRKEILAKLE
KLRQVTGNET--LGLEEQDLEGDFDPIQHEQLMQKCLGHDFYSAEEEEKPQFEEEDG---
-LE

ENSGT00390000005605_0_Linker_0_2 (544, 672)

EDWNWDTWGGPEQD-GA------WN--QQEPHCEDPNFNMDADYDPSQPQ-------
---------KKW---------------LEAPSTGRKKRK--------SLFASAVGQQ---
--KPVFDPG-D

PF12936 // ENSGT00390000005605_0_Domain_2 (672, 763)

KTFEEYLDEYYRLDYEDIIDDLPCRFKYRSVVPCDFGLSTEEILGADDK
ELNRWCSLKKTC----MYRSEQEELQDKRSYSQKAQNSRKKRQIFKSLCPEETE---TAT
EDT--GELQRHPAGPQ-----------------------------EQLVVPDGGRG----
KQSQPES--PL----------------AQE---DEAPMSPHKTP-APQKRRR-GKKAHLL
GPTVTLGGREFSRQRLQAFGLNPKRLHFRQLGRQRRKQPGPKSRP-------------

------------------------------------------------------------
MPEPRGQSPLRVNKAFAARYGRYREREELQRLKDRYGDRDG--GGDSSSESDSSEECVEF
DPQQERDF--YRTLSLLKKKDPRIYQKDATFYQRTVSSS----SSESEQGPAAS----GK
QKKVWPMYLKDYERKVILEKGGKYVDEENSDGESADQRLQ-----QTSSQSYVE------
--EQKQLR---ESFRPFMED-SESEDSAGEGGSGLLQKHR-KTQEEQAQEDTDYVEWLKG
QKEIQNPESLKEL------------MHLKEYWDNPDLDEGEQFLRDYILNKRYEEEGD--
---E----EEEEEEEEEGVPGPPVQLAVDDSSDEGELFLKKQEDFEHKYNFRFEEPDAAS
VKTYPRSIASSVRRRDERRKEKREETR

PF05178 // ENSGT00390000005605_0_Domain_0 (448, 544)

ERKKREKA---KKREELKQLKNLKRKEILAKLE
RLRQVTGNET--LGLEEQDLEGDFDPAQHEQLMQKCLGDDFYGAAEEEKPQFEEEDG---
-LE

ENSGT00390000005605_0_Linker_0_2 (544, 672)

EDWNWDMWGGPKQD-SV------WS--QQEPHCEDPDFNMDADYDPSQPR-------
---------KKR---------------REAPSTGKKKRK--------SPFAEAVGQE---
--KPVFSPG-D

PF12936 // ENSGT00390000005605_0_Domain_2 (672, 763)

KTFEEYLDEYYRLDYEDIIDDLPCRFKYRRVLPCDFGLSTEEILAADDK
ELNRWCSLKKTC----MYRSEQEELQDKRAYSQKARNFQKKRQIFQSLCPEEME---TAT
EAT--GELQGDRAGPR-----------------------------EQLLAPDRGHG----
ERPQPEK--PP----------------AQE---DEAPALPSKTP-VPHKRRR-GKKARLL
GPTVTLGGHEFSRQRLQAFGLNPKRLHFRQLGRQRRKQQRPKSCPGGQDGKARGSPGS

------------------------------------------------------VALRAA
MPEPRGSSPLRVNAAFAARYGRYREREELQRLKDRYGDRDS--GGDSSSESDSSDDRVXX
XXXXXXXXXXXXXXXXXXX--------XXXXXXXXXXXXXXXSSSESEEETAAS----EE
KKKERPMYLKDYERKVILEKEGKYVDEEDSDGETSHGRLQ-----PLSSQSYVE------
--EQNQLK---ESFRAFVED-SEDEDSAGEGGSGLLQKRA-KTRDEKAQEEADYVEWLKG
QKEIQNPESLKEL------------THLKEYWNNPELDEGERFLRDYILNKRYEEEADED
EE-------EEEEEEEEGVPGPPVQLVVDDSSDEGELFLKKQEDFEHKYNFRFEEPDSAS
VKTYPRSIASSVRRKDERRKEKREETRERKRRXXX---XXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXX

PF05178 // ENSGT00390000005605_0_Domain_1 (514, 767)

XKCFGAEYYGTAEEEKPQFEEEEG---
-LEDDWNWDTWDGSGQD-GA------WS--QQEPHCEDPDFNMDADYDPSQQR-------
---------RKK---------------REAPLTGKKKRK--------SPFAEAVGQE---
--KPVFDPE-DKTFEEYLDEYYRLDYEDIIDDLPCRFKYRTVMPCDFGLSTEEI-AADDK
ELNRWCSLKKTC----MYRSEQEELQDKRAYTQKAQNSWKKRQIFKSLCPEETE---TAT
EAT--GKPQREKVGSQ-----------------------------GQLPAPDGGWK----
---GPES--PP----------------AQE---AAS-LSPESAP---Q------------
----------------------------------------------------------

------------------------------------------------------MGHRAA
MPEPRGSSQLRVNTAFAARYNRYREREELQRLKDRYGDRDS--GSDSSSESDSSDERVEF
DPQQERDF--YKTLSLLKKKDPRIYQKDATFYNRTA------SSSDSEEEPAAS----EK
QKKVRPMYLKDYERKVILEKAGKYVDEENSDGETSNHRLQ-----ETSSQSYVE------
--EQKQLK---ESFRAFVED-SEDEDSAGEGGSSLLQKRA-KTRQEKAQEEADYIEWLKG
QKEIRNPESLKEL------------THLKEYWNDPELDEGERFLRDYILNKRYEEEEDEE
ED-E------EKEEEEEGVPGPPVQLAVDDSSDEGELFLKKQEDFEQKYNFRFEEPDSTS
VKTYPRSIASSVRRKDERRKEKREETR

PF05178 // ENSGT00390000005605_0_Domain_0 (448, 548)

ERKKREKA---KKQEELKQLKNLKRKEILAKLE
KLRKVTGNDT--LGLEEGDLEDDFDPAQHDQLMQKCFGDEYYGAVEEEKPQFEEEE----
GLEDDWN

ENSGT00390000005605_0_Linker_0_2 (548, 672)

WDTWDGPEQE-GD------WS--QQELHCEDPNFNVG-----SPRG-------
---------PD-----------------GGPLDG---------------------QEE-P
GSLALSRAG-D

PF12936 // ENSGT00390000005605_0_Domain_2 (672, 762)

KTFEEYLDEYYRLDYEDIIDDLPCRFKYRTVVPCDFGLSTEEILAADDK
ELNRWCSLKKTC----MYRSEQEELRDKRAYSQKAQNSWKKRQVFKSLCREE--AE-MPA
EAT--GKPQRDGAGPQ-----------------------------RQLPGLDGAGG----
KRPRPES--PP----------------AQE---EEAPVSPHKKP-APQRRRR-AKKARLL
GPTVMLGGREFSRQRLQAFGLNPKRLYFRQLGRQRRK-QGPKNSS-------------

------------------------------------------------------VVRRAA
MPEPRGASPLRVN-AFAARYSRYREREELQRRCARHARPAPE--SHRPQGNPLSPPHGEF
DPQQDRDF--YRTLSLLKQKDPRIYQKDATFYQRAAS-------SSEEEEPAAP----EE
QKRPQPMYLKDYERAVILEKGGKYVDSHMREGRCSLQRLQ-----QTSSKSYVD------
--EQKQLK---ESFRAFVED-SEDEDSAGEGGSGLLQKRA-KSREEKAQEEADWFPK--S
ARSGPRPPSLPIL------------THLKEYWNNPELDEGERFLRDYILNKRCYVTEGEH
P----------PRPPVPRVPGPRVQLAVDDSSDEGELFLKKQADFEHKYNFRFEEPDSAS
VKTYPRTIASSVRRKDERRKEKREETRERKKREKA---KKQEELKQLKNLKRKEILAKLE
KLRQVTGNQT--LG

PF05178 // ENSGT00390000005605_0_Domain_1 (495, 767)

LEEQDLEGDFDPARHDQLMQKCFGDEYYGAAEEEKPQFEDEEG---
-LEDDWNWDRWDGQEQD-GA------WS--QQEPHCEDPDFNMDADYDPSQQR-------
---------KQR---------------HKPPVTGKKKRK--------SPFAAAVGQE---
--KPAFEPG-DQTFEEYLDEYYRLDYEDIIDDLPCRFKYRSVVPCDFGLSTEEILAADDK
ELNRWCSLKKTC----MYRSEQEELQDKRAYSQKAQNTWKKRQIFKSLCSEETE---VPT
EAV--RKPQGDKAGSR-----------------------------GQLPAPDGAQG----
KRPRPES--PP----------------TQE---GEAPVAPTKKP-AAQRRRR-GKTARLL
GPTVTLGGREFSRQRLQAFGLNPKRLHFRQLGRQRKKQRAAEGLP-------------

------------------------------------------------------------
MPEPRGSSPLRVNAAFAARYGRYREREELQRLKDRYGDRDS--GGDSSSESDSGDERVEF
DPQQERDF--YRTLSLLKKKDPRIYQKDATFYQRTVSSS---ESEE---APAAK----EK
QKKMRPMYLKDYERKVILEKEGKYIDEENSDEETSNQRFQ-----QISSKSYVE------
--EQKQLK---ESFRAFVED-SESEDSAGEGGSGLLQKRA-KTREEKAQEDADYVEWLKG
QKEIHNTDTLQEL------------THLKEYWNDPELDEGERFLRDYILNKHYEEEEEGE
E---------EEEEEEEAGPSLPVQLAVDDSSDEGELFLKKQEDFEHKYNFRFEEPDSAW
VKTYPRSVASSVRRKDERRKERREETR

PF05178 // ENSGT00390000005605_0_Domain_0 (448, 548)

ERKRREKA---KKQEELKQLKNLKRKEILAKLE
RLRQVTGNET--LGFEEKDLEDDFDPAQHDQLMQRCFGDEYYGTTEEEKPQFEEEEGL--
E--DDWN

ENSGT00390000005605_0_Linker_0_2 (548, 672)

WDTWAGPEQG-GA------WS--QQEPHCEDPDFNMDADYDPSQPR-------
---------KKR---------------REAPLTGKKKRK--------SPFASAVGQE---
--KPVFNPG-D

PF12936 // ENSGT00390000005605_0_Domain_2 (672, 762)

KTFEEYLDEYYRLDYEDIIDDLPCRFKYRTVVPCDFGLSTEEILAADDK
ELNRWCSLKKTC----MYRSEQEELQDKRAYSQKAQNSWKKRQIFKSLCP---EGTETLT
EAT--GKPQRDKADPP-----------------------------GQLLAPDGACG----
QRPQPGS--PP----------------AQE---EAGPVSPTQKP-VPHRRRR-GKKARLL
GPTVTLGGREFSRQRLQAFGLNPKRLHFRQLGRQRRKQQGPKSSP-------------

------------------------------------------------------MGHRAA
MPEPRGSSQLRVNTAFAARYNRYREREELQRLKDRYGDRDS--GSDSSSESDSSDERVEF
DPQQERDF--YKTLSLLKKKDPRIYQKDATFYNRTA------SSSDSEEEPAAS----EK
QKKVRPMYLKDYERKVILEKAGKYVDEENSDGETSNHRLQ-----ETSSQSYVE------
--EQKQLK---ESFRAFVED-SEDEDSAGEGGSSLLQKRA-KTRQEKAQEEADYIEWLKG
QKEIQNPESLKEL------------THLKEYWNDPELDEGERFLRDYILNKRYEEEEDEE
----------EKEEEEEGVPGPPVQLAVDDSSDEGELFLKKQEDFEQKYNFRFEEPDSTS
VKTYPRSIASSVRRKDERRKEKREETR

PF05178 // ENSGT00390000005605_0_Domain_0 (448, 541)

ERKKREKA---KKQEELKQLKNLKRKEILTKLE
KLRKVTGNDT--LGLEEGDLEDDFDPAQHDQLMQKCFGDEYYGAVEEEKPQFEEEE----

ENSGT00390000005605_0_Linker_0_2 (541, 672)

GLEGTG---LGTGDWQE-GD------WS--QQELHCEDPNFNVGVTGWGSPRG-------
---------PD-----------------GGPLDG---------------------QEE-P
GSLALSRAG-D

PF12936 // ENSGT00390000005605_0_Domain_2 (672, 762)

KTFEEYLDEYYRLDYEDIIDDLPCRFKYRTVVPCDFGLSTEEILAADDK
ELNRWCSLKKTC----MYRSEQEELRDKRAYSQKAQNSWKKRQVFKSLCREE--AE-MPA
EAT--GKPQRDGAGPQ-----------------------------RQLPGLDGAGG----
KQPRPES--PP----------------AQE---EEAPVSPHKKP-APQRRRR-AKKARLL
GPTVMLGGREFSRQRLQAFGLNPKRLYFRQLGRQRRKQQGPKNSS-------------

------------------------------------------------------VGRAAA
MPEPRGSSPLRVNAAFAARYGRYREREELQRLKDRYGDRDR--GGDSSSESDSSDERVEF
DPQQERDF--YRTLSLLKKKDPRIYQKDATFYQKTVSSS---ESEEAEEVPTAK----EK
QKKMRPMYLKDYERKVILEKEGKYVDEENSDAETSNQRFQ-----QISSKTYVE------
--EQKQLK---ESFRAFVED-SE-DDSAGEGGSGLLQKRA-KTKEEKAQEEADYVEWLKG
QKEICNPDALKEL------------THLKEYWNNPELDEGERFLRDYILNKRYEEEEEEG
EE-E----EEEEEGEEEGGPGLPVQLTVDDSSDEGELFLKKQEDFEHKYNFRFEEPDSAL
VKTYPRSIASSVRRKDERRKEKREET

PF05178 // ENSGT00390000005605_0_Domain_0 (447, 545)

RERKRREKA---KKQEELKQLKNLKRKEILAKLE
RLRQVTGNET--LGFEERDLEDDFDPAQHDQLMQRCFGDEYYGTTEEEKPQFEEEAGL--
EESD

ENSGT00390000005605_0_Linker_0_2 (545, 672)

DWNWDTWAGPEQG-GA------WN--EQELHCEDPDFNMDADYDPSQPQ-------
---------KRQ---------------REAPLTGKKKRK--------SPFAAAVGQE---
--KPVFDPG-D

PF12936 // ENSGT00390000005605_0_Domain_2 (672, 765)

KTFEEYLDEYYRLDYEDIIDDLPCRFKYRTVVPCDFGLSTEEILAADDK
ELNRWCSLKKTC----MYRSEQEELQDKRAYSQKAQNSWKKRQIFKSLCCVLRNRTETLT
EAT--GKPQKDKAGPQ-----------------------------GQLLALDGACG----
QQPQPGS--PP----------------VQE---EASPVPHTQKP---QGRRR-GKKARLL
GPTVTLGGHEFSRQRLQAFGLNPKRLHFRQLARQRRKHRGPKSRP-------------

------------------------------------------------------VGRRAA
MPEPRAASPLRVNSAFAARYGRYREREELQRR----------------------------
-----EYF--YRTLSLLKKKDPRIYQKDATFYQRTAS------SSESEEEPAAS----EK
QKKARPMYLKDYERKVILEKEGKYVDEENSDVETSNQRLQ-----RTSSQSYVE------
--EQKQLK---EGFRAFVED-SEDEDSAGEGGSGLLQKRA-KTREEKAQEEADYMEWLKG
HKELQSPESLEEL------------THLKEYWNDPELEEGERFLRDYILNKRYEEEGDED
EE-E----E-EEEEEE--KGVTPVQLAVEDSSDEGELFLKKQEDFEHKYNFRFEEPDSAS
VKTYPRSIASSVRRKDERRKEKREETR

PF05178 // ENSGT00390000005605_0_Domain_0 (448, 548)

ERKKREKA---KKREELKQLKNLKGREILAKLE
KLRKVTGNDT--LGFEEGDLEDDFDPARHDQLMQKCFGDEYYGTAEEEKPRFEEEEG---
-LEDDWN

ENSGT00390000005605_0_Linker_0_2 (548, 673)

WDSWDGTDQD-GA------WS--QQEPHCEDPDFNMDADYDPSQQR-------
---------KKK---------------REAPSTGKKKRK--------SPFAAAVGQE---
--KPVFDPG-DK

PF12936 // ENSGT00390000005605_0_Domain_2 (673, 762)

TFQEYLDEYYRLDYEDIIDDLPCRFKYRTVVPCDFGLSTEEILAADDK
ELNRWCSLKKTC----MYRSEQEELQDKRAYSQKAQNSWKKRQIFKSLCPET----ETPT
EAT--GKPQRDKGVPQ-----------------------------EQLAVPDAACR----
KRPRPES--PP----------------AQE---EEAPVSPTQKP-APQRRKR-GKKARLL
GPTVTLSGREFSRQRLQAFGLNPRRLHFRQLGRQQRKQQRPKGGS-------------

------------------------------------------------------------
MPEPRASASLRVNAAFAARYSRYREREELQRLKDRYGDPDGG-D--SSSESDSSDEHVVS
FHKQASRLSLTGTLGLLGR--------PCQ----FTETS----SSDSEEEPAAS----GK
QKKIQPMYLKDYERKVILEKEGKYVDEDNSDGETFDHRLK-----ETAVKSYVE------
--EQKQLK---ESFRAFVED-SSDEDSAAEGGSGLLRKHV-KTGEEKAQEEVDYLEWLKG
QKEIDSSESLKEL------------THLKEYWNSPELDEGEQFLRDYILNKRYEEEEEEE
-----------EEIEEEGAPGPTGQLAVDDSSDEGELFLRKQEDFEHKYNFRFEEPDSAS
VKTYPRSIASSVRRKDERRKEKREETR

PF05178 // ENSGT00390000005605_0_Domain_0 (448, 548)

ERKKREKA---RKREELKQLKNLKRKEILAKLE
KLRQVTGNET--LGLEEQDLEGDFDPAQHDQLMQKCLGDGFYGTTEEEKPHFEEDEG---
-LEDDWN

ENSGT00390000005605_0_Linker_0_2 (548, 673)

WDTWSGPEQD-GA------WN--QQELHCEDPDFNMDADYDPSQPR-------
---------KKL---------------REAPSSGKKKRK--------SPFAAAVGQQ---
--KPTFDPGEDK

PF12936 // ENSGT00390000005605_0_Domain_2 (673, 762)

TFDEYLDEYYRLDYEDIIDDLPCRFKYRSVVPCDFGLSTEEILAADDK
ELNRWCSLKKTC----MYRSEQEEMQEKRVYSQKAQNVWKKRQIFKSLCQEEME---MPT
EAP--GKSQ-GSASPQ-----------------------------AQLP--EGACG----
KRPQSGT--LV----------------AKE---EELAHTPCPEKPASQ-RQQ-SKKARLL
GPTVTLGGHKFSRQRLQAFGLNPKRMHFRQLGRQRRKQQSHP----------------

--------------------------------MRAGPRAAPPRPGR--PQCACAMGHRAA
MPEPRGSSQLRVNTAFAARYNRYREREELQRLKDRYGDRDS--GSDSSSESDSSDERVEF
DPQQERDF--YKTLSLLKKKDPRIYQKDATFYNRTA------SSSDSEEEPAAP----EK
QKKVRPMYLKDYERKVILEKAGKYVDEENSDGETSNHRLQ-----ETSSQSYVE------
--EQKQLK---ESFRAFVED-SEDEDSAGEGGSSLLQKRA-KTRQEKAQEEADYIEWLKG
QKEIGNPESLKEL------------THLKEYWNDPELDEGERFLRDYILNKRYEEEEDEE
ED-E----E-EKEEEEEGVPGPPVQLAVDDSSDEGELFLKKQEDFEQKYNFRFEEPDSTS
VKTYPRSITSSVRRKDERRKEKREETR

PF05178 // ENSGT00390000005605_0_Domain_0 (448, 548)

ERKKREKA---KKQEELKQLKNLKRKEILAKLE
KLRKVTGNDT--LGLEEGDLEDDFDPAQHDQLMQKCFGDEYYGAVEEEKPQFEEEE----
GLEDDWN

ENSGT00390000005605_0_Linker_0_2 (548, 672)

WDTWDGPEQE-GD------WS--QQELHCEDPNFNMDADYDPSQPR-------
---------K-K---------------REAPSTGKKKRK--------SPFAAAVGQE---
--KPVFEPG-D

PF12936 // ENSGT00390000005605_0_Domain_2 (672, 763)

KTFEEYLDEYYRLDYEDIIDDLPCRFKYRTVVPCDFGLSTEEILAADDK
ELNRWCSLKKTC----MYRSEQEELRDKRAYSQKAQNSRKKRQVFKSLCREE--AE-MPA
EAT--GKPQRDGAGPQ-----------------------------RQLPGLDGAGG----
KRPRPES--PP----------------AQE---EEAPVSPHKKP-APQRRRR-AKKARLL
GPTVMLGGREFSRQRLQAFGLNPKRLYFRQLGRQRRKQQGPKNSS-------------

------------------------------------------------------------
MPEPHGSASLRVNAAFAARYSRYREREELQRLKDRYGDPD-G-S-DSSSESDSSDEHVEF
DPQQERDF--YRTLSLLKKKDPRIYQKDATFYQRTAETS----SSESEEEPAAS----EK
QKKMQPMYLKDYERKVILEKEGKYVDEDNSDGETFDHRLK-----ETSMKSYVE------
--EQRQLK---ESFRAFVED-SSDEDSAAEGGSGLLRKHT-KSGEEKAQEEVDYLEWLKG
QKEIHSSESLKEL------------THLKEYWNSPELDEGEQFLRDYILNKRYEEEEEEE
------------DMEEEGVPGPTVQLAVDDSSDEGELFLRKQEDFEHKYNFRFEEPDSAS
VKTYPRSIASSVRRKDERRKEKREETR

PF05178 // ENSGT00390000005605_0_Domain_0 (448, 548)

ERKKREKA---KKQEELKQLKNLKRKEILAKLE
KLRQVTGNET--LGLEEQDLEGDFDPAQHDQLMQKCLGDGFYGTAEEEKPHFEEEEG---
-LEDDWN

ENSGT00390000005605_0_Linker_0_2 (548, 672)

WDTWSGPKQD-GA------WS--QQEPHCEDPDFNMDADYDPSQPQ-------
---------KKL---------------REAPSSGKKKRK--------SPFAAAVGQQ---
--KPMFDPED-

PF12936 // ENSGT00390000005605_0_Domain_2 (672, 762)

KTFEEYLDEYYRLDYEDIIDDLPCRFKYRTVVPCDFGLSTEEILAADDK
ELNRWCSLKKTC----MYRSEQEEMQEKRAYSQKAQNLWKKRQIFKSLCGEEME---MPT
EAT--GKSQ-GKASPQ-----------------------------AQLPVPNGACG----
KRPQSET--HV----------------AKE---EELAHTSYPEKPTSQ-RQK-SKKARLL
GPTVTLGGHKFSRQRLQAFGLNPKRLHFRQLGRQRRKQQSNP----------------

------------------------------------------------------------
MPEPRGSSPLRVNAAFAARYGRYREREELQRLKDRYGDQDG--SGDSSSESDSSDERVEF
DPQQERDF--YRTLSLLKKKDPRIYKKDATFYQRTASS-----SES-EEEPAAE----EK
QKKVCPMYLKDYERKVILEKGGKYVDEENSDGETSDQRLQ-----QTSAKSYVE------
--EQKQLK---ESFRAFVED-SEDEDSAGEGGSRLLQKRA-KSREEKAQEDADYIEWLKG
QKEIQNSDTLKEL------------THLREYWNNPELDEGERFLRDYILNKRYEEEGDEE
EE-E-----EEEEEEEDRVPGPPVQLAVDDSSDEGELFLKKQEDFEHKYNFRFEEPDSAL
VKTYPRNIASSVRRKDERRKERREETR

PF05178 // ENSGT00390000005605_0_Domain_0 (448, 548)

ERKKREKA---RKQEELKQLKNLKRKEILAKLE
RLRQVTGNET--LGFEEQDLEDDFDPARHDQLMQKCFGDEYYGTAEEEKPQFEEEEGL--
E--DDWN

ENSGT00390000005605_0_Linker_0_2 (548, 672)

WDTWAGPEQG-GA------WS--QPELHCEDPDFNMDADYDPSQPR-------
---------KKH---------------REAPSLGKKKRK--------SPFATAVGQE---
--KPVFDPG-D

PF12936 // ENSGT00390000005605_0_Domain_2 (672, 762)

KTFEEYLDEYYRLDYEDIIDDLPCRFKYRTVVPCDFGLSTEEILAADDK
ELNRWCSLKKTC----MYRSEQEELQDKRSYSQKAQNTWKKRQIFKSLCSEETE--TATT
EAT--RKPQRDKAGLQ-----------------------------GQLLPPDGACG----
KQPRPES--PP----------------AQE---EEASVPPAKKP-APQRRRR-GKKARLL
GPTVTLGGREFSRQRLQAFGLNPKRLHFRQLGRQQRKQQGPKSSP-------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------THLKEYWSNPKLDEGEKFLRDYILNKGYEEEEEEE
EEDE------EEEEEEDRFAGAGGQLVLQDSSDEGELFLKKQEDFERKYNFRFEEPGSEA
VMTYPRTISTSVRRKDERRKEKREEMRERKKKEKA---KKQEELKQLKNLKRREILAKLE
KLREITGNET--VGF

PF05178 // ENSGT00390000005605_0_Domain_1 (496, 767)

NEDDLEEDFDPAQHDQLMQKCFGDEFYGVGEEEKPQFEEEEG---
LDDEEWNWDTWTDTG-----------GG---NELHCEDPDFNVGPSAVPRYP---GGKRR
D-AL---------------------------QLGKNKRK--------SYFSQAMTRE---
--KPSFDPE-ARTFEQYLDEFYQLDYEDIIDDLPCRFKYRSVLPCDFGLSTEEILAADDK
ELNRWCSLKKTC----MYRSEQEELRDKKAFSLKGQNTWKKQQILKSLTTESKDPK---E
EESPAEEEEDDEAGVR-------------------------------SEEPVEKRSRVGT
SSA--------A---------------EPSTLPTPAPPA-GSGESQRSRKKR-LWLKAKL
GERVKLGGREFSRGRLQAYGLNPRRLHYRQLLREKRKRQPRA----------------

------------------------------------------------------------
MPEPHGSASLRVNAAFAARYSRYREREELQRLKDRYGDPD-G-GGDSSSESDSSDEHVEF
DPQQERDF--YRTLSLLKKKDPRIYQKDATFYQRTAETS----SSESEEEPAAS----GK
QKKVEPMYLKDYERKVILEKEGKYVDEDNSDGETFDQRLK-----ETSSKSYVE------
--EQKQLK---ESFRAFVED-SSDEDSAGEGGSGLLRKHT-KSREEKAQEEVDYVEWLKG
QKEIHSSETLKEL------------THLKEYWNSPGLDEGEQFLRDYILNKRYEEEEEEE
----------EEEEMEDGVPGPPVQLAVDDSSDEGELFLKKQEDFEHKYNFRFEEPDSAS
VKTYPRSIASSVRRKDERRKEKREETR

PF05178 // ENSGT00390000005605_0_Domain_0 (448, 548)

ERKKREKA---RKQEELKQLKNLKRKEILAKLE
KLRQVTGNET--LGLEEQDLEDDFDPAQHDQLMQKCFGDAFYGTAEEEKPQFEEEEG---
-LEDDWN

ENSGT00390000005605_0_Linker_0_2 (548, 672)

WDTWGGPEQD-GG------WS--QQGLHCEDPDFNMDADYDPRQPR-------
---------KKL---------------REAPSTGKKKRK--------SPFAAAVGQQ---
--KPMFDPGD-

PF12936 // ENSGT00390000005605_0_Domain_2 (672, 762)

KTFEEYLDEYYRLDYEDIIDDMPCRFKYRTVVPCDFGLSTEEILAADDK
ELNRWCSLKKTC----MYRSEQEEMQEKRAYSQKAQNLWKKRQIFKSLCQEETD---MPT
EAT--GKSR-GKANSQ-----------------------------EQLPMPDGTCG----
KRLQSES--QV----------------AK-----ELAHTASPEKPASQ-RQK-NKKARLL
GPTVTLGGHKFSRQRLQAFGLNPKRLHFRQLGRQRRKQQSHP----------------

------------------------------------------------------------
MPEPHGSASLRVNAAFAARYSRYREREELQRLKDRYGDPD-G-S-DSSSESDSSDEHVEF
DPQQERDF--YRTLSLLKKKDPRIYQKDATFYQRTAETS----SSESEEEPAAS----EK
QKKMQPMYLKDYERKVILEKEGKYVDEDNSDGETFDHRLK-----ETSMKSYVE------
--EQRQLK---ESFRAFVED-SSDEDSAAEGGSGLLRKHT-KSGEEKAQEEVDYLEWLKG
QKEIHSSESLKEL------------THLKEYWNSPELDEGEQFLRDYILNKRYEEEEEEE
------------DMEEEGVPGPTVQLAVDDSSDEGELFLRKQEDFEHKYNFRFEEPDSAS
VKTYPRSIASSVRRKDERRKEKREETR

PF05178 // ENSGT00390000005605_0_Domain_0 (448, 548)

ERKKREKA---KKQEELKQLKNLKRKEILAKLE
KLRQVTGNET--LGLEEQDLEGDFDPAQHDQLMQKCLGDGFYGTAEEEKPHFEEEEG---
-LEDDWN

ENSGT00390000005605_0_Linker_0_2 (548, 672)

WDTWSGPKQD-GA------WS--QQEPHCEDPDFNMDADYDPSQPQ-------
---------KKL---------------REAPSSGKKKRK--------SPFAAAVGQQ---
--KPMFDPED-

PF12936 // ENSGT00390000005605_0_Domain_2 (672, 762)

KTFEEYLDEYYRLDYEDIIDDLLCRFKYRTVVPCDFGLSTEEILAADDK
ELNRWCSLKKTC----MYRSEQEEMQEKRAYSQKAQNLWKKRQIFKSLCGEEME---MPT
EAT--GKSQ-GKASPQ-----------------------------AQLPVPNGACG----
KRPQSET--HV----------------AKE---EELAHTSYPEKPTSQ-RQK-SKKARLL
GPTVTLGGHKFSRQRLQAFGLNPKRLHFRQLGRQRRKQQSNP----------------

----------------------------------------------------------AA
MPEPRGKCQLRVNEAFAARYGRYRQREELQKLKDRYGDRPESSG-DSDSDSDSSEERVEF
DPELDKGF--YRTLSLLKKKDPRIYQEGATFYNEAVIEH-----SSSEEDEKPS----EK
KKKEKPMYLKDYERKVILEKEGKYVDEEDSDQEAKRQKHQ-----I-SDLTQTNQISKLP
WKNPTHITER----VAMLTH-IQRHSIEGRYRSDTYNKRMKERKQNATQXEADYVDWLKG
QTDTDDQEGLREL------------THLREYWSNPKLDDGEKFLRDYILNRGYEEEVVEE
EEDNAEDEDDSEEEDNKRFPSAGGQLRVDDSSDEGELFLRKQEDFERKYNFRFEEPDSEQ
VKTYPRTIASSVRRKDERRKEKREATRERKKKEKL---KKQEELKQLKNLKRQEILDKLE
KLREITGNEDGGFGF

PF05178 // ENSGT00390000005605_0_Domain_1 (496, 766)

EEADLEGDFDPAMHDQLMQKCFGDEYYGVGEEEKPQFEEEEGFD-
VKPDVWNWDTWTGAEGN-GA------WREEAAEPHCEDPDFNMDADYDPSQPTIRSGKK-
--------KKKWD--------G--------PMTGKKRRK--------SHFAEVVSQE---
--RPVFDPE-DKTFEEYLDEYYRLDYEDIIDDLPCRFKYRSVVPCDFGLTTEEILASDDK
ELNRWCSLKKTC----MYRSEQEELREQKQYSLKAKNTRKKHQILQSLAQQTEETP---G
PV---PTPRKRDQGP----------------------------------EPLEVPKAQGP
ATPAT----MAT---------------QKQD---GAEPQ-VASSSRPKKSLR-GKKGRLL
GPRVKLGGFEFSHQRLQAYGLNAKRLHYRQLGRERKKRARAQAQA-------------

------------------------------------------------------------
----------XVNAAFAARYSRYREREELQRLKDRYGDRDDG--SDSSSESDSSDEHVEF
DPQQERDF--YRTLSLLKKKDPRIYQKDATFYQRTAEAS----SSESEEESAAL----GK
QKKVQPMYLKDYERKVILEKEGASVDGSHVEGRWTKGRRK-----YCEIKIHLK------
--LQIRLQ---ASGEAWLAATVTNERRAGHGGTVINQRNS-LPDTHGLLRDRDLAQWQSP
C-LGSSSEGHKEV------------THLKEYWNNPELDEGEQFLRDYILNKRYEEDEEEE
T---------EEERVELGVLGPPVQLAVDDSSDEGELFLKKQEDFEHKYNFRFEEPDSAS
VKTYPRSIASSVRRKDDRRKEKREETR

PF05178 // ENSGT00390000005605_0_Domain_0 (448, 548)

ERKKREKA---KKQEELKQLKNLKRKEILAKLE
KLRQVTGNET--LGLEEQDLEDDFDPAQHDQLMQKCFGDAFYGTVEEEKPQFEEEEG---
-LEDDWN

ENSGT00390000005605_0_Linker_0_2 (548, 672)

WDTWGGPEQN-GA------WS--QQELHCEDPDFNMDADYDPSQPR-------
---------KKL---------------REAPTSGKRKRK--------SPFAAAVGQE---
--KPMFDPGD-

PF12936 // ENSGT00390000005605_0_Domain_2 (672, 762)

KTFEEYLDEYYRLDYEDIIDDLPCRFKYRTVVPCDFGLSTEEILSADDK
ELNRWCSLKKTC----MYRSEQEEMQEQRAYSQKAQSVWKKRQIFKSLCQEEVE---MPT
EAT--GKSP-SKASSQ-----------------------------VQLPMPSAAGG----
KKPQAEL--SG----------------AKE---EELAHTPCPEKPASQ-KQK-SKKARLL
GPTVTLGGHKFSRQRLQAFGLNPKRLHFRQLGRQRKKQQSHA----------------

--------------------------------MWAGPRAAPPRPGR--PQCACAMGHRAA
MPEPRGSSQLRVNTAFAARYNRYREREELQRLKDRYGDRDS--GSDSSSESDSSDERVEF
DPQQERDF--YKTLSLLKKKDPRIYQKDATFYNRTA------SSSDSEEEPAAL----EK
QKKVRPMYLKDYERKVVLEKAGKYVDEDNSDRETSNHRLQ-----ETSSQSYVE------
--EQKQLK---ESFRAFVED-SEDEDSAGEGGSSLLQKRA-KTRQEKAQEEADYIEWLKG
QKEIRNPESLKEL------------THLKEYWNDPELDEGERFLRDYILNKRYEEEEDEE
E-----------EEEEEGVPGPPVQLAVDDSSDEGELFLKKQEDFEQKYNFHFEEPDSAS
VKTYPRSIASSVRRKDERRKEKREETR

PF05178 // ENSGT00390000005605_0_Domain_0 (448, 548)

ERKKREKA---KKQEELKQLKNLKRKEILAKLE
KLRKVTGNET--LGLEEGDLEDDFDPAQHDQLMQKCFGDEYYGAVEEEKPQFEEEE----
GLEDDWN

ENSGT00390000005605_0_Linker_0_2 (548, 672)

WDTWDGPEQE-GD------WS--QQELHCEDPNFNMDADYDPSQLR-------
---------K-K---------------REAPSTGKKKRK--------SPFATAVGQE---
--KPVFEPG-D

PF12936 // ENSGT00390000005605_0_Domain_2 (672, 762)

KTFEEYLDEYYRLDYEDIIDDLPCRFKYRTVVPCDFGLSTEEILAADDK
ELNRWCSLKKTC----MYRSEQEELQDKRAYSQKAQNSWKKRQVFKSLCREE--AE-TPA
EAT--GKPQRDEAGPQ-----------------------------RQLPVLDGAGG----
KRPRPES--PP----------------AQE---EEAPVSLHKKP-APQRQRR-AKKARLL
GPTVMLGGREFSRQRLQAFGLNPKRLYFRQLGRQRRK-QGPKNSS-------------

------------------------------------------------------LAPVAA
MPEPRGASPLRVNAAFAARYSRYREREELQRLKDRYGDRDG---DDSSSESDSSDERVEF
DPQQERDF--YRTLSLLKKKDPRIYQKDATFYQSPXXXXXXXXXXXXXXXXXXX----XX
XXXX----X-------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXPASFKSYVE------
--EQQQLK---ESFRAFVEG-SEDEDSAGEGGSGLLQKRA-KSQEEKAQEEADYVEWLKG
RKEARDPESLKEL------------TYLREYWNNPELEEGEQFLRDYILNKRYEEEEEEE
E-----------EEEEECIPGPPVQLAVDDSSDEGELFLKKQEDFEHKYNFRFEEPDSAS
VKTYPRSIASSVRRKDERRKEKREETRERKRREKA---KKQEELKQLKNLKRKEILAKLE
KLRQVTGNET--LG

PF05178 // ENSGT00390000005605_0_Domain_1 (495, 767)

LEEQDLEEDFDPARHDQLMQKCFGDEYYGATEEEKPQFEEEEG---
-LEDDWNWDRWDGPEQD-GA------WS--QHEPHCEDADFNMDADYDPSQPR-------
---------KKQ---------------LRPPTSGKKKRR--------SPFAAAVGQE---
--KPVFDPG-DKTFEEYLDEYYRLDYEDIIDDLPCRFKYRSVVPCDFGLSTEEILAADDK
ELNRWCSLKKTC----MYRSEQEELQDKRAYSQKARNTWKKRQIFKSLCAEGTE---VPT
EAT--RKPQGDEASAL-----------------------------GPLSAPDGSQG----
KRPRPES--PP----------------AQE---DGAPESAPKKP-VPQKRRK-SKKAQLL
GPTVTLGGHEFSRQRLQAFGLNPKRLHFRQLSRQQRRKQGSKGLH-------------

------------------------------------------------------------
MPEPRASGCLKVNAAFAARYSRYREREELQRLKDRYGDPDVG--GDSSSESDSSDEHVEF
DPQQERDF--YRTLSLLKKKDPRIYQKDATFYQRTAEAS----SSESEEEPPAALGKQEK
QQKQQPMYLKDYERKVILEKGGKYVDEDNSDGETVDHRLQ-----ETSTKSYVE------
--EQKQLK---ESFRAFVED-SSDEDSAGEGGSGLLQKHT-KSREEKAQEEVDYLEWLKG
QKDMDSSESLKEL------------THLKEYWNNPGLDKGEQFLRDYILNKRYEEEEEEE
----------EEEEEEEGAPGPPVQLAVDDSSDEGELFLKKQEDFEHKYNFRFEEPDSAS
VKTYPRSIASSVRRKDERRKEKREETR

PF05178 // ENSGT00390000005605_0_Domain_0 (448, 547)

ERKKREKA---RKQEELKQLKNLKRKEILAKLE
KLRQATGNET--LGLEEQDLEADFDPAQHDQLMQKCFGDAFYGTAEEEKPQFEEEDG---
-LEDDW

ENSGT00390000005605_0_Linker_0_2 (547, 672)

NWDMWGGPEQD-GA------WS--QQELHCEDPDFNMDADYDPSQPR-------
---------KKL---------------REAPTSGKRKRK--------SPFAAAVGQE---
--KPMFDPGD-

PF12936 // ENSGT00390000005605_0_Domain_2 (672, 762)

KTFEEYLDEYYRLDYEDIIDDLPCRFKYRTVVPCDFGLSTEEILSADDK
ELNRWCSLKKTC----MYRSEQEEMQEQRVYSQKAQNMWKKRQIFKSLCQEEME---MST
EAT--GKSQ-SKASPQ-----------------------------VQLFTPNGADQ----
KTPQAET--LV----------------SKE---EGLAHTSCPEKPASQ-KQK-SKKARLL
GPTVTLGGHKFSRQRLQAFGLNPKRLHFRQLGRQRKKQQSHS----------------

------------------------------------------------------------
MPEPRGSSPLRVNKAFAARYGRYREREELQRLKDRYGDRDS--GGDSSSESDSSDERVEF
DPQQERDF--YRTLSLLKKKDPRIYQKDATFYQRPE----------SEQERAAS----GR
QKKVRPMYLKDYERTVIVEKGGKYVDEENSDGESSDWRLQ-----QTTSQSYVE------
--EQKQLR---ESFRPFVED-SEDEDSAGEGGSSLLQKRR-KTREEKAQEDADYVEWLKG
QKEVQNPESLKEL------------MHLKQFWDNPELDEGEQFLRDYILNKRYEEEGD--
---E----DEEEEEEEEGAPGPPAQLAVDDSSDEGELFLKKQEDFEHKYNFRFEEPDAAS
VKTYPRSITSSVRRRDERRKEKREETR

PF05178 // ENSGT00390000005605_0_Domain_0 (448, 544)

ERKKKEKA---RKREELKQLKNLKRKEILAKLE
KLRQVTGNRT--LGLEEQDLEGDFDPAQHEQLMQKCLGDDFYGAEEEEKPQFEEEDG---
-LE

ENSGT00390000005605_0_Linker_0_2 (544, 672)

EDWNWDTWGGPQQNSGA------WS--QQELHCEDPDFNMDADYDPSQSR-------
---------KRQ---------------REAPSTGKKKRK--------SPFAEAVGQE---
--KPVFNPG-D

PF12936 // ENSGT00390000005605_0_Domain_2 (672, 763)

KTFEEYLDEYYRLDYEDIIDDLPCRFKYRRVVPCDFGLSTEEILAAEDR
ELNRWCSLKKTC----MYRSEQEELQDQRAYSQKARNSQKKRQIFRSLCPEGME---TAR
EAT--GQQQGHTAGPR-----------------------------EQLPAPDRGHG----
QRPRPES--AP----------------AQD---KEAPALPRKTP-APQKRRS-GRKARLL
GPTVTLGGREFSRQRLQAFGLNPKRLHFRQLRRLRGKR--------------------

------------------------------------------------------------
------------------------------------------------------------
------------XXXXXXXXXXXXXXXXXTFYQRTESSS----SSESEQEAAAS----GK
QKKVLPMYLKDYERKVILEKGGKYVDEENSEGESSDGRRQ-----QTWSQTYVE------
--EQKQLQ---ESFRPFMED-SEDEDSAGEGGSGLLQKRR-KTREEKAQEDADYVEWLKG
QKEIENPESLKEL------------MHLKEYWDNPELDAGEQFLRDYILNKRYKEEEG--
---------DEEEEEEEGVLGPPVQLAVDDSSDEGELFLKKQEAFEHKYNFRFEEPDSAS
VKTYPRSIASSVRRKDERRKEKREETR

PF05178 // ENSGT00390000005605_0_Domain_0 (448, 544)

ERKKREKA---RKREDLKQLKNLKRKEILAKLE
QLRQVTGNAT--LGLEEQDLEGDFDPAQHEQLMQKCLGDDFYGAVEEEKPQFEEEDG---
-LE

ENSGT00390000005605_0_Linker_0_2 (544, 672)

EDWNWDTWAGPERD-GV------WS--QQEPHCEDPDFNMDADYDPSQPQ-------
---------KKQ---------------REAPATGRKKRR--------SPFAAAVGQE---
--KPVFNPG-D

PF12936 // ENSGT00390000005605_0_Domain_2 (672, 763)

KTFEEYLDEYYRLDYEDIIDDLPCRFKYRRVVPCDFGLSTEEILAADDK
ELNRWCSLKKTC----MYRSEQEELQDQRAYSQKARNSRKKQQIFRSLGPEEMG---TAT
DAT--GEPQRHAAGPR-----------------------------E--------------
-QPQPEH--PL----------------AQE---EEAPVVPCKTP-VPSKRRR-GKKARLL
GPTVTLGGREFSRQRLQAFGLNPKRLHFRQLDRQRRKRQGPKSRP-------------

------------------------------------------------------------
--------------------------RLCSAVRDRYGDRDS--GGDSSSESDYSDERVDF
DPQQDRDF--YRTLSLLKKKDPCIYQKDATFYQGTA------SSSDSEEEPAVP----EK
QKKVQPMYLKDYERKVILEKEGKYVDEENSDGEASSQRLQ-----QTSSQSYVD------
--EQKQLK---ESFRAFVED-SEDEDSSGEGGSGLLQKRT-KTREEKAQEEADYIEWLKG
QKEVQNLESLKELSVTQVLSPLHPQAHLKEYWNNPELDEGERFLRDYILNKRYEEEGDEE
EE-E-------EEEEEEGIPGPPVQLAVDDSSDEGELFLKKQEDFEHKYNFRFEEPDSAS
VKTYPRSIASSVRRKDERRKEKREETR

PF05178 // ENSGT00390000005605_0_Domain_0 (448, 546)

ARKKREKA---KKQEELKQLKNLKRKEILAKLE
KLRKVTGNET--LGFEEGDLEDDFDPARHDQLMQKCFGDEYYGTTEEEKPQFEEEE----
GLEED

ENSGT00390000005605_0_Linker_0_2 (546, 672)

WNWDTWDGPEQD-GA------WS--QQELHCEDPDFNMDADYNPSQPR-------
---------RKR---------------REAPSTGKKKRK--------SPFAAAVGQE---
--KPVFDPG-D

PF12936 // ENSGT00390000005605_0_Domain_2 (672, 762)

KTFEEYLDEYYRLDYEDIVDDLPCRFKYRTVVPCDFGLSTEEILAADDK
ELNRWCSLKKTC----MYRSEQEELQDKRAYGQKAQNAWKKQQIFKSLCQEE--TE-MPT
EAT--GKPHRDQAQPQ-----------------------------GQLLASDGASG----
QQPWPES--RP----------------AQE---EEAPT----------QKRR-RKKARLL
GHTVTLGGREFSHQRLQAFGLNPKRLHFRHLGRQQRKQRASKSSS-------------

------------------------------------------------------------
MPEPRASSPLRVNAAFAARYNRYREREELQRLKDRYGDRDGDDDGDSSSESGSSDERVEF
DPQQERDF--YRTLSLLKKKDPRIYQKDATFYHRKA------SSSSENEEPSAF----EK
PKKVRPMYLKDYERKVILEKEGKYIDEENSDGETFDQRLK-----HTSSQSYVE------
--EQKQLK---ESFRAFVED-SSGEDSAEEGGSGLLQKHV-KTREEKVQEEADYVEWLKG
QKDIQNPESLREL------------VHLKEYWSNPELDEGEQFLRDYILNKRYEEES---
-------------EEEEGVPCPPVQLAVDDSSDEGELFLKKQEDFEHKYNFRFEEPDSAL
VKTFPRSIASSVRRKDERRKEKREETR

PF05178 // ENSGT00390000005605_0_Domain_0 (448, 548)

ERKKKEKA---KKQEELKQLKNLKRKEILAKLE
KLRQVTGNET--LGLAEQDLEGDFDPAQHDQLMQKCFGDAFYGTAEEEKPQFEEEE----
GLEDDWN

ENSGT00390000005605_0_Linker_0_2 (548, 672)

WDTWGGPEQN-GA------WS--QQEPHCEDPDFNMDADYDPSQRQ-------
---------KKK---------------REAPSSGKKKRK--------SPFAAAVGQE---
--KPVFDPG-D

PF12936 // ENSGT00390000005605_0_Domain_2 (672, 762)

KTFEEYLDEYYRLDYEDIIDDLPCRFKYRTVVPCDFGLSTEEILAADDK
ELNRWCSLKKTC----MYRSEQEELQEKRAYTQKAQNAWKKRQIFKSLCQEE--ME-TPK
EAT--GNPQEGNASPQ-----------------------------AQLPGPDEARG----
KQPRPES--PP----------------AQE---EEAP---TEKP-APQRRKR-GKKARLL
GPTVTLGGHEFSRQRLQAFGLNPKRLHFRQLRWRQRKQQGRKSCP-------------

------------------------------------------------------VVRRAA
MPEPRGSSPLRVNAAFAARYGRYREREELQRLKDRYGDRDS--GGDSSTESDSSGELVEF
DPQQERDF--YRTLSLLKKKDPRIYEKDATFYQKTVSSS---ESEEAEAVPVAK----EK
PKKMRPMYLKDYERKVILEKEGKYVDEENSDAETPDQRFQ-----QISSQSYVE------
--EQKRLK-ERDSFRAFVED-SDDEDSAGEGGSGLLQKRA-KTREEKAQEDADYVEWLKG
QKEIRNPDTLREL------------THLKEYWNDPELDEGERFLRDYILNKRYEEEEGEE
E--------EGEEEEEEGGPSLPVQLAVDDSSDEGELFLKKQEDFEHKYNFRFEEPDSAL
VKTYPRSIVSSVRRKDERRKERRDETRERKKREKA---KKREELKQLKNLKRKEILAKLE
RLRQVTGNET--LG

PF05178 // ENSGT00390000005605_0_Domain_1 (495, 767)

FEERDLEDDFDPSRHDQLMQRCFGDEYYGTTEEEKPQFEEEEGL--
EETDDWNWDTWAGPEQE-GA------WN--PQELHCEDPDFNMDADYDPSQPR-------
---------KKP---------------REAPLTGKKKRK--------SPFAAAVGQE---
--KPVFDPG-DKTFEEYLDEYYRLDYEDIIDDLPCRFKYRTVVPCDFGLSTEEILAADDK
ELNRWCSLKKTC----MYRSEQEELQDKRAYSQKAQNSWKKRQIFKSLCP---DETETLK
EAT--GKPQRDKDGPQ-----------------------------GQLLVPDGAGG----
KQPQPGS--PP----------------AQE---EAGPMSHTQKP-VPQRQRR-GKKARLL
GPTVTLGGHEFSRQRLQAFGLNPKRLHFRQLGRQRRKPQGPKSGP-------------

------------------------------------------------------------
MPEPRAS---AVNAAFAARYGRYREREELQRLKDRYGDPDSG-G--SGSDSDSSDELVAF
DPQQERDF--YRTLSLLKKKDPRIYQKDVTFYQRTASSS----SSESEEDPGAS----EK
QKKAKPMYLKDYERKVILEKEGKYVDEENSDGEPSDQRLK-----QNLSETYVE------
--EQKQLK---ESFRAFIED-SEDEDGTGDSGSGLLKKHT-KTKEEKAQEEADYVEWLKG
QKEIQNPESTKEL------------EHLKEYWNNPELDEGEQFLRDYILNKRYEEEGEED
E---------EEEEEEEEAPGPPVQLAVDDSSDEGELFLKKQEDFEHKYNFRFEEPDSAS
VKTFPRNIASSVRRKDERRKEKREETR

PF05178 // ENSGT00390000005605_0_Domain_0 (448, 548)

ERKKREKA---RKQEELKQLKNLKRKEILAKLE
KLRQVTGNDR--LGLEEQDLEDDFDPGRHEQLMQKCFGDEFYGAAEEEKPQFEEEEG---
-FEDDWN

ENSGT00390000005605_0_Linker_0_3 (548, 673)

WDTWAGAG------------S--KEEPHCEDADFNMDADYDPHQPR-------
---------KKK---------------REAPATGKKKRK--------TPFAAAVGQE---
--KPVFDPGH-S

PF12936 // ENSGT00390000005605_0_Domain_3 (673, 713)

TFEQYLDEYYRLDYEDIIDDLPCRFKYRSVIPCDFGLSTEE-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------

------------------------------------------------------------
MPEPRASGCLKVNAAFAARYSRYREREELQRLKDRYGDPDVG--GDSSSESDSSDEHVEF
DPQQERDF--YRTLSLLKKKDPRIYQKDATFYQRTAEAS----SSESEEEPSAALGKQE-
--NLQPMYLKDYERKVILEKGGKYVDEDNSDGETVDHRLQ-----ETSTKSYVE------
--EQKQLK---ESFRAFVED-SSDEDSAGEGGSVLLQKHT-KSREEKAQEEVDYLEWLKG
QKEMDSSESLKEL------------THLKEYWNNPGLDEGEQFLRDYILNKRYEEEEEE-
------------EEEEEGAPGPPVQLAVDDSSDEGELFLKKQEDFEHKYNFRFEEPDSAS
VKTYPRSIASSVRRKDERRKEKREETR

PF05178 // ENSGT00390000005605_0_Domain_0 (448, 547)

ERKKREKA---RKQEELKQLKNLKRKEILAKLE
KLRQVTGNET--LGLEEQDLEADFDPAQHDQLMQKCFGDAYYDTAEEEKPQFEEEDG---
-LEDDW

ENSGT00390000005605_0_Linker_0_2 (547, 672)

NWDMWGGHEQD-GA------WS--QQELHCEDPDFNMDADYDPSQPR-------
---------KKL---------------REAPTSGKRKRK--------SPFAAAVGQE---
--KPMFDPGD-

PF12936 // ENSGT00390000005605_0_Domain_2 (672, 762)

KTFEEYLDEYYRLDYEDIIDDLPCRFKYRAVVPCDFGLSTEEILSADDK
ELNRWCSLKKTC----MYRSEQEEMQEQRVYSQKAQNMWKKRQIFKSLCQEEME---TST
EAT--GKSQ-SKASPQ-----------------------------VQLPTPNGADR----
KVPQAET--LV----------------SKE---EGLAHTSCPEKPASQ-KQK-SKKARLL
GPTVTLGGHKFSRQRLQAFGLNPKKLHFRQLGRQRKKQQSHS----------------

------------------------------------------------------VGHRAA
MPEPHGSSLLRVNAAFAARYNRYREREELQRLKDRYGDRDS--GGDSSSESDSSDERVVF
DPQQERDF--YRTLSLLKKKDPRIYQKDATFYQRTA------SSSDSEEEPAAS----EK
QKKVQPMYLKDYERKVILEKEGKYVDEENSDGETSNHRLQ-----RTSSQSYVE------
--EQKQLK---ESFRAFVED-SEDEDSAGEGGSSLLQKRA-KTRQEKAQEEADYIEWLKG
QKEIRNPESLKEL------------THLKEYWNNPELDEGEQFLRDYILNKRYEEEEDEE
ED----------EEEDEGVPGPPVQLAVDDSSDDGELFLKKQEDFEHKYNFRFEEPDSAS
VKTYPRSIASSVRRKDERRKEKREETR

PF05178 // ENSGT00390000005605_0_Domain_0 (448, 548)

ERKKREKA---KKQEELKQLKNLKRKEILAKLE
KLRKVTGNET--LGLEERDLEDDFDPAQHDQLMEKCFGDEYYGAVEEEKPQFEEEE----
GLEDDWN

ENSGT00390000005605_0_Linker_0_2 (548, 672)

WDTWDGSEQD-GD------WS--Q---HCEDPDFNMDADYDPSQPR-------
---------KKK---------------HEAPLTSKKKRK--------SPFAAAVGQV---
--KPVFEPG-D

PF12936 // ENSGT00390000005605_0_Domain_2 (672, 762)

KTFEEYLDEYYRLDYEDIIDDLPCRFKYRTVVPCDFGLSTEEILAADDK
ELNRWCSLKKTC----MYRSEQEELRDKRAYSQKAQNSWKKQQIFKSLCREE--------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------

------------------------------------------------------------
MPEPRGSSPLRVNKAFAARYGRYREREELQRLKDRYGDPHG--GSDSSSESDSSDERVEF
DPQQERDF--YRTLSLLKKKDPRIYQKDATFYQRTESPS----SSENEEESAAP----QK
RKKVQPMYLKDYERKVILEKGGKYVDEENSDGETSDQRVQ-----QTSSQSYVE------
--EQKQLR---DSFRPFVED-SEDEDSAGEGGSGLLQKRR-KTREEKDQEDADYVEWLKG
QKEIQNRKSLKEL------------MHLKEYWDNPELDEGEQFLRDYILNKRYEEEDE--
--------EEEEEEEEEGVPGPPVQVAVDDSSDEGELFLKKQEDFEHKYNFRFEEPDAAL
VKTYPRSIASSMRRRDERRKEKREETR

PF05178 // ENSGT00390000005605_0_Domain_0 (448, 544)

ERKKREKA---RKQEELKQLKNLKRKEILAKLE
KLRQVTGNET--LGLEEQDLEGDFDPIQHEQLMQKCLGHDFYSAEEEEKPQFEEEDG---
-LE

ENSGT00390000005605_0_Linker_0_2 (544, 672)

EDWNWDTWGGPEQD-GA------WN--QQEPHCEDPNFNMDADYDPSQPR-------
---------KKW---------------LEAPSTGRKKRK--------SLFASAVGQQ---
--KPVFDPG-D

PF12936 // ENSGT00390000005605_0_Domain_2 (672, 763)

KTFEEYLDEYYRLDYEDIIDDLPCRFKYRSVVPCDFGLSTEEILGADDK
ELNRWCSLKKTC----MYRSEQEELQDKRSYSQKAQNSRKKRQIFKSLCPEETE---TAT
EDT--GELQRHPAGPQ-----------------------------EQLVVPDGGRG----
KQSQPES--PL----------------AQE---DEAPMSPHKTP-APQKRRR-GKKAHLL
GPTVTLGGREFSRQRLQAFGLNPKRLHFRQLGRQRRKQPGPKSRP-------------

------------------------------------------------------------
MPEPRGSGSLRVNAAFAARYSRYREREELQRLKDRYGDPGDG-DGDSSSESDSSDEHVEF
DPQQERDF--YRTLSLLKKKDPRIYQKDATFYQRTAETS----SSESEEEPAAS----GK
QKKVQPMYLKDYERKVILEKEGKYVDEDDSDEETFDPRRK-----ETATRTYVE------
--EQKQLK---ESFRAFVED-SGDEDSAGEGASGLLQRHT-ESGEEKAREEVDYLEWLKG
QKEIDGSESLKEL------------THLKEYWNSPGLDEGEQFLRDYILNKRYEEEEEE-
------------EEEEEGVPGPPVQLAVDDSSDEGELFLRKQEDFEHKYNFRFEEPDSAS
VKTYPRSIASSVRRKDERRKEKREETR

PF05178 // ENSGT00390000005605_0_Domain_0 (448, 548)

ERKKREKA---RKREELKQLKNLKRKEILAKLE
KLRQVTGNET--LGLEEQDLEDDFDPAQHDQLMQKCFGDAFYGTAEEEKPQFEEEEG---
-LEDDWN

ENSGT00390000005605_0_Linker_0_2 (548, 672)

WDTWGGPEQD-GA------WS--QQELHCEDPDFNMDADYDPSQPR-------
---------KKL---------------REAPSSGKKKRK--------SPFAAAVGQQ---
--KPTFDPGD-

PF12936 // ENSGT00390000005605_0_Domain_2 (672, 762)

KTFEEYLDEYYRLDYEDIIDDLPCRFKYRTVVPCDFGLSTEEILAADDK
ELNRWCSLKKTC----MYRSEQEEMQERRVYSQKAQNLWKKRQIFKSLCQEEME---MPT
EAT--GKSQ-GKAGPQ-----------------------------ARLSVADGSQS----
LASSHKL--QV----------------AKE---EEFTHTPCPEKPASQ-RQK-NKKARLL
GPTVTLGGHKFSRQRLQAFGLNPKRLHFRQLGRQRRKQQSHP----------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------MHLKDYERKVILEKAGKYVDEENSDGETSNHRLQ-----ETSSQSYVE------
--EQKQLK---ESFRAFVED-SEDEDSAGEGGSSLLQKRA-KTRQEKAQEEADYIEWLKG
QKEIGNPESLKEL------------THLKEYWNNPELDEGERFLRDYILNKRYEEEEDEE
ED-E----E-EKEEEEEGVPGPPVQLAVDDSSDEGELFLKKQEDFEQKYNFRFEEPDSTS
VKTYPRSIASSVRRKDERRKEKREETR

PF05178 // ENSGT00390000005605_0_Domain_0 (448, 548)

ERKKREKA---KKQEELKQLKNLKRKEILAKLE
KLRKVTGNDT--LGLEEGDLEDDFDPAQHDQLMQKCFGDEYYGAVEEEKPQFEEEE----
GLEDDWN

ENSGT00390000005605_0_Linker_0_2 (548, 672)

WDTWDGPEQE-GD------WS--QQELHCEDPNFNMDADYDPSQPR-------
---------K-K---------------REAPSTGKKKRK--------SPFAAAVGQE---
--KPVFEPG-D

PF12936 // ENSGT00390000005605_0_Domain_2 (672, 763)

KTFEEYLDEYYRLDYEDIIDDLPCRFKYRTVVPCDFGLSTEEILAADDK
ELNRWCSLKKTC----MYRSEQEELRDKRAYSQKAQNSRKKRQVFKSLCREE--AE-MPA
EAT--GKPQRDGAGPQ-----------------------------RQLPGLDGAGG----
KRPRPES--PP----------------AQE---EEAPVSPHKKP-APQRRRR-AKKARLL
GPTVMLGGREFSRQRLQAFGLNPKRLYFRQLGRQRRKQQGPKNSS-------------

------------------------------------------------------MGHRAA
MPEPARVVQLRVNAAFAARYNRYREREELQRLKDRYGDRES--GSDSSSESDSSDERVEF
DPQQEQDF--YKTLSLLKKKDPRIYQKDATFYNRTA------SSSESEEEPAAL----EK
QKKVRPMYLKDYERKVILEKAGKYVDEENSDGETSNHRLQ-----ETSSQSYVE------
--EQKQLK---ESFRAFVED-SEDEDSAGEGGSSLLQKRA-KTRQEKAQEEADYIEWLKG
QKEIRNPESLKEL------------THLKEYWNDPELDEGERFLRDYILNKRYEEEEEE-
--------E-EKEEEEEGVPGPPVQLTVDDSSDEGELFLKKQEDFEQKYNFRFEEPDSAS
VKTYPRSIASSVRRKDERRKEKREETR

PF05178 // ENSGT00390000005605_0_Domain_0 (448, 541)

ERKKREKA---KKQEELKQLKNLKRKEILAKLE
KLRKVTGNET--LGLEEGDLEDDFDPAQHDQLMQKCFGDEYYGAVEEEKPQFEEEE----
GLEGEISWGTG-------------------------------LGIGDWGLDPG-------
---------LN-----------------PRQA---------------------------L
G----------------------------------RFTMP--------------------
------------------------------------------LLSPPVKLGM--AE-TPA
EAT--GKPQRDEAGPQ-----------------------------RQLPALDGAGG----
KRPRPES--PP----------------AQE---EEAPVSPHKKP-APQRRRR-AKKARLL
GPTVMLGGREFSRQRLQAFGLNPKRLHFRQLGRQLRKQQGPKNSS-------------

------------------------------------------------------MGHRTA
MPEPRGSSQLRVNAAFAARYNRYREREELQRLKDRYGDRDS--SSDSSSESDSSDERVEF
DPQQERDF--YKTLSLLKKKDPRIYQKDATFYNRTA------SSSDSEEDPEAL----EK
QKKVRPMYLKDYERKVILEKAGKYVDEENSDGETSNHRLQ-----ETSSQSYVE------
--EQKQLK---ESFRAFVED-SEDEDGAGEGGSSLLQKRA-KTRQEKAQEEADYIEWLKG
QKEIRNPDSLKEL------------THLKEYWNDPELDEGERFLRDYILNKRYEEEEEEE
ED-E----E-E-MEEEEGVHGPPVQLAVDDSSDEGELFLKKQEDFEQKYNFRFEEPDSAS
VKTYPRSIASSVRRKDERRKEKREETR

PF05178 // ENSGT00390000005605_0_Domain_0 (448, 548)

ERKKREKA---KKQEELKQLKNLKRKEILAKLE
KLRKVTGNEM--LGLEEGDLEDDFDPAQHDQLMQKCFGDEYYGAVEEEKPQFEEEE----
GLEDDWN

ENSGT00390000005605_0_Linker_0_2 (548, 672)

WDTWDGPEQE-GD------WS--QQELHCEDPNFNMDADYDPSQPR-------
---------KKK---------------REAPLTGKKKRK--------SPFAAAVGQE---
--KPVFEPG-D

PF12936 // ENSGT00390000005605_0_Domain_2 (672, 762)

KTFEEYLDEYYRLDYEDIIDDLPCRFKYRTVVPCDFGLSTEEILAADDK
ELNRWCSLKKTC----MYRSEQEELRDKRAYSQKAQNSWKKRQVFKSLCREE--AE-TPA
EAT--GKPQRDEAGPQ-----------------------------RQLPALDGSLM----
G---PES--PP----------------AQE---EEAPVSPHKKP-APQKRRR-AKKARLL
GPTVMLGGCEFSRQRLQAFGLNPKRLHFRQLGRQRRKQQGPKNSS-------------

------------------------------------------------------VGCRVA
MPEPRAASPLRVNSAFAARYSRYREREELQRLKDRYGDRDS--GGDSTSESDSSDDRVEF
DPQEEHDF--YRTLSLLKKKDPYIYQKDATFYQRPAS------STESQEEPGAS----EK
QKKVQPMYLKDYKRKVILEKEGKYIDEDNSDGETSDQRLQ-----KTSSQSYVE------
--EQKQLK---ESFRVFVED-SEDEDSAGEGTSVLLQKRA-KTSEEKAQEEADYVKWLKG
QKGIQNPESLKEL------------THLKEYWDDPELEEGEQFLRDYILNKRYEEEGDEN
EE-E----K-EEEEEEKGVTGPPVQLSVDDSSDEGELFLKKQEDFEHKYNFRFQEPDSAS
VKTYPRSITSSVRRKDERRKEKREETRERKKRVSV---RWPAGSGSP---------ACCE
SPHSWLGTKK--KGGES----SASQVLSPAVT

PF05178 // ENSGT00390000005605_0_Domain_1 (513, 767)

LQKCFGDEYYRTAEEEKPQFEEEEGI--
EEPDDWNWDTWDGPEQD-GT------WS--QQEPHCEDPNFNMDADYDLSQQK-------
----------KK---------------REAPLMGKKKRK--------SHFAAAVGQE---
--KPVFDPG-DKTFEEYLNDYYRLDYEDIIDDLPCRFKYRNVVPCDFGLSTEEILAADDK
ELNRWCSLKKTC----MYRSEQEELQDKRAYSQKAQNSWKKRQIFKSLCSEKTE---IPT
EAT--GKPQRDKAVPQ-----------------------------EQLPVPDVSWG----
KQPQPKS--LP----------------AQE---EEAPVSRTQQP-APKKQKR-GKKARLL
GCTVTLGGREFSCQRLQAFGLNPKRLHFRQLGRQRKKQ--------------------

------------------------------------------------------------
MSDPRGFPALRVNAAFAARYRRYREREELQRLRDRYGDPDS--GGDSSSESDSSDERVEF
DPKQERDF--YRTLSLLKKKDPRIYQKDVTFYQRTVSSS----SSESEEEPPAS----GK
QKKVRPMYLKDYERKVILEKEGKYIDEDNSDGDTISDRLK-----ETSSKSYVE------
--EQKHLK---ESFRAFMED-SSDEDGVGEGGSGLLQKHT-KSQEEKAQEDTDYLEWLKG
QKEIQDPESLKEL------------AHLKEYWNNPELDEGEQFLRDYILNKGYEEEEE--
------------EEKEEGVPGPPVQLAVDDSSDEGELFLKKQEDFEHKYNFRFEEPDSAS
VKTYPRSIASSVRRKDERRKEKREETR

PF05178 // ENSGT00390000005605_0_Domain_0 (448, 548)

ERKRREKA---RKREELKQLKNLKRKEILAKLE
KLRQVTGNET--LGLEEQDLEEDFDPAKHDQLMQKCFGDAFYSTAEGEKPQFEEEEG---
-LEDDWN

ENSGT00390000005605_0_Linker_0_2 (548, 673)

WDTWDGTVQD-GA------WS--QQEPHCEDPDFNMDADYDPREPR-------
---------KKR---------------LEATSSGKKKRK--------SPFAAAVGQE---
--KPMFDPG-NK

PF12936 // ENSGT00390000005605_0_Domain_2 (673, 762)

TFQEYVDEYYQLDYEDIIDDLPCRFKYRSVVPCDFGLTTEEILAADDK
ELNRWCSLKKTC----MYRSEQEELQERWAYSQKAQNTWKKRQVFKSLCQEM----EIPS
EAA--GRP--------------------------------------QLPLPERAFG----
KQAWSET--PP----------------AQE---EGKSRVSPPEKPVHQRRKK-GKKSRLL
GPTVTLGGHEFSRQRLQAFGLNPRRLHFRQMGRQKRKQLGSKSCP-------------

------------------------------------------------------MGHRAA
MPEPRGSSQLRVNAAFAARYNRYREREELQRLKDRYGDRDS--SSDSSSESDSSDERVEF
DPQQERDF--YKTLSLLKKKDPRIYQKDATFYNRTA------SSSDSEEDPEAL----EK
QKKVRPMYLKDYERKVILEKAGKYVDEENSDGETSNHRLQ-----ETSSQSYVE------
--EQKQLK---ESFRAFVED-SEDEDGAGEGGSSLLQKRA-KTRQEKAQEEADYIEWLKG
QKEIRNPDSLKEL------------THLKEYWNDPELDEGERFLRDYILNKRYEEEEE--
---E----E-E-MEEEEGVHGPPVQLAVDDSSDEGELFLKNQEDFEQKYNFRFEEPDSAS
VKTYPRSIASSVRRKDERRKEKREETR

PF05178 // ENSGT00390000005605_0_Domain_0 (448, 548)

ERKKREKA---KKQEELKQLKNLKRKEILAKLE
KLRKVTGNET--LGLEEGDLEDDFDPAQHDQLMQKCFGDEYYGAVEEEKPQFEEEE----
GLEDDWN

ENSGT00390000005605_0_Linker_0_2 (548, 672)

WDTWDGPEQE-GD------WS--QQELHCEDPNFNMDADYDPSQPR-------
---------KKK---------------REAPLTGKKKRK--------SPFAAAVGQE---
--KPVFEPG-D

PF12936 // ENSGT00390000005605_0_Domain_2 (672, 762)

KTFEEYLDEYYRLDYEDIIDDLPCRFKYRTVVPCDFGLSTEEIFAADDK
ELNRWCSLKKTC----MYRSEQEELRDKRAYSQKAQNSWKKRQVFKSLCREE--AE-TPA
EAT--GKPHRDEAGPQ-----------------------------RQLPALDGSLM----
G---LES--PP----------------AQE---EEAPVSPHKKP-APQKRRR-AKKARLL
GPTVMLGGCEFSRQRLQAFGLNPKRLHFRQLGWQRRKQQGPKNSS-------------

------------------------------------------------------------
MPEPRASGCLKVNAAFAARYSRYREREELQRLKDRYGDPDVG--GDSSSESDSSDEHVEF
DPQQERDF--YRTLSLLKKKDPRIYQKDATFYQRTAEAS----SSESEEEPPAALGKQE-
--KQQPMYLKDYERKVILEKGGKYVDEDNSDGETVDHRLQ-----ETSTKSYVE------
--EQKQLK---ESFRAFVED-SSDEDSAGEGGSGLLQKHT-KSREEKAQEEVDYLEWLKG
QKDMDGSESLKEL------------THLKEYWNNPGLDKGEQFLRDYILNKRYEEEEEE-
------------EEEEEGAPGPPVQLAVDDSSDEGELFLKKQEDFEHKYNFRFEEPDSAS
VKTYPRSIASSVRRKDERRKEKREETR

PF05178 // ENSGT00390000005605_0_Domain_0 (448, 547)

ERKKREKA---RKQEELKQLKNLKRKEILAKLE
KLRQVTGNET--LGLEEQDLEADFDPAQHDQLMQKCFGDAFYGTAEEEKPQFEEEDG---
-LEDDW

ENSGT00390000005605_0_Linker_0_2 (547, 672)

NWDMWGGPEQD-GA------WS--QQELHCEDPDFNMDADYDPSQPR-------
---------KKL---------------REAPTSGKRKRK--------SPFAAAVGQE---
--KPMFDPGD-

PF12936 // ENSGT00390000005605_0_Domain_2 (672, 762)

KTFEEYLDEYYRLDYEDIIDDLPCRFKYRTVVPCDFGLSTEEILSADDK
ELNRWCSLKKTC----MYRSEQEEMQEQRVYSQKAQNMWKKRQIFKSLCQEEME---MST
EAT--GKSQ-SKVSPQ-----------------------------VQLPTPNGADQ----
KTPQAET--LV----------------SKE---EGLAHTSCPEKPASQ-KQK-SKKARLL
GPTVTLGGHKFSRQRLQAFGLNPKRLHFRQLGRQRKKQQSHS----------------

------------------------------------------------------------
MPEPRGSSQLRVNTAFAARYNRYREREELQRLKDRYGDRDS--GSDSSSESDSSDERVEF
DPQQERDF--YKTLSLLKKKDPRIYQKDATFYNRTA------SSSDSEEEPAAL----EK
QKKVRPMYLKDYERKVVLEKAGKYVDEDNSDRETSNHRLQ-----ETSSQSYVE------
--EQKQLK---ESFRAFVED-SEDEDSAGEGGSSLLQKRA-KTRQEKAQEEADYIEWLKG
QKEIRNPESLKEL------------THLKEYWNDPELDEGERFLRDYILNKRYEEEEDEE
-------------EEEEEVPGPPVQLAVDDSSDEGELFLKKQEDFEQKYNFRFEEPDSAS
VKTYPRSIASSVRRKDERRKEKREETR

PF05178 // ENSGT00390000005605_0_Domain_0 (448, 548)

ERKKREKA---KKQEELKQLKNLKRKEILAKLE
KLRKVTGNET--LGLEEGDLEDDFDPAQHDQLMQKCFGDEYYGAVEEEKPQFEEEE----
GLEDDWN

ENSGT00390000005605_0_Linker_0_2 (548, 672)

WDTWDGPEQE-GD------WS--QQELHCEDPNFNMDADYDPSQLR-------
---------K-K---------------REAPSTGKKKRK--------SPFATAVGQE---
--KPVFEPG-D

PF12936 // ENSGT00390000005605_0_Domain_2 (672, 762)

KTFEEYLDEYYRLDYEDIIDDLPCRFKYRTVVPCDFGLSTEEILAADDK
ELNRWCSLKKTC----MYRSEQEELQDKRAYSQKAQNSWKKRQVFKSLCREE--AE-TPA
EAT--GKPQRDEAGPQ-----------------------------RQLPVLDGAGG----
KRPRPES--PP----------------AQE---EEAPVSLHKKP-APQRQRR-AKKARLL
GPTVMLGGREFSRQRLQAFGLNPKRLYFRQLGRQRRK-QGPKNSS-------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-MHP-FSPTNFPQ------------APLKEYWNDPKLDEGERFLRDYILNKRYKEAGDGE
EEEEE------EEDGIKEIGLPEKQLAVSDSSDEGELFLKKQEDFERKYNFRFEEPEAQV
VQTYPRIIATSVRRKDERRKEKRQEIRERKKKKER--EQKQEELKQLKNLKRREIVERLE
KLQEITGSEA--GTF

PF05178 // ENSGT00390000005605_0_Domain_1 (496, 767)

QEGDLDGDFDPAQHDWLMEKFFGDEYYGVGEEEKPQFEAEEG---
-IDDEWNWDKWTGEDGA-EAEADMCFQGEDENEPHCEDPDFIMDADYDPSQQPGPSKRK-
---------RKL----------------DIPLLGKKKRK--------SHFAQAIGQK---
--KEPFDPE-TKTFEQYLDEFYGLDYEDLIGDLPCRFKYRTVVPCSYGLTTEEILAADDK
ELNRWCSLRKTC----MFRSENEELRDKTIYEKKGQDAWKKKQILKSLQAEPEEAE---D
VKKTQSKKG-----KK-------------------------------SREKAKH-----C
ELPAQKM--QLG---------------SPGCEEEGSPCF-AHPSVQRPKKKR-GRKGLVL
GTKVRVGGAEFSRQRLQAYGLNPKRLHYRQLLREKRRKKPLGGP--------------

------------------------------------------------------------
------------------------------------------------------------
-------------------------------------SS-----EEDGRPPEKE----KK
KKREKPMYLKDYERKVILEKEGKYVDEEDSDQEAERQKHR-----QTTSRSYIE------
--EQKR---LKESFRQFVAD-SDEEESAGEGGSSLLKKRT-KTKEEKAREEADYVDWLKG
QKDAEDKEDLKEL------------THLREYWSNPQLDDGEKFLRDYILNKGYQEEEEEE
EEEE---------EEDEGFPGAGGQLVVFTLVTNGEALLLGHLHRALTYLFLSYKAWAGE
VKTYPRTITSSVRRKDERRKEKREATRERKKKQSFFKCGSRSQLKQLKNLKRREILDKLE
KLREITGNQA--GAF

PF05178 // ENSGT00390000005605_0_Domain_1 (496, 766)

EEADLEGDFDPSTHDQLMQKCFGEEYYGIGEEEKPQFEEEEGFD-
VKPDEWNWDTWTGAE-------------EEAAEPHCEDPDFIMDADYDPSQPSVRSGKKK
--------KKKWD----------------VPLAGKKRRK--------SHFAEVVSQD---
--RPVFDPE-NKTFEEYLDEYYRLDYEDIIDDLPCRFKYRSVVPCDFGLTTEEILASDDK
ELNRWCSLKKTC----MYRSEQEELREQKQYNLKAKNIRKKQQILQSLAQLTEETS---D
PAHPLRKRQGPEALN----------------------------------ESRKKPKLEGT
SEEEEEE--DFL---------------VPKDKSMAPLAA-AETQEKPKKSLR-SKKGRLL
GPRVKLGGFEFSHQRLQAYGLNAKRLHYRQLGRERKKRARAQPQA-------------

------------------------------------------------------------
MPEPRGSSPLRVNAAFAARYGRYREREELQRLKDRYGDRDS--GGDSSSESDSSDERVEF
DPQQERDF--YTTLSLLKKKDPRIYQKDATFYQKTVSSS---ESEEAEE---AE----KK
QKKMRPMYLKDYERKVILEKEGKYVDEENSDAESSDRRFP-----QLTSQSYVE------
--EQKQLK---ESFRAFVED-SDDEDSAGEGGSGLLQKRA-QTKEEKAQEDADYVEWLKG
QKEIDNPDTLKEL------------THLKEYWSNPELDEGERFLRDYILNKRYEEEEDEE
E--------EEEAEEEEGGPGLPVQLAVDDSSDEGELFLKKQEDFEHKYNFRFEEPDSAL
VKTYPRSIASSVRRKDERRKEKREETRERKRREKA---KKQEELKQLKNLKRKEILAKLE
RLRQVTGNET--LGF

PF05178 // ENSGT00390000005605_0_Domain_1 (496, 767)

EERDLEDDFDPARHDQLMQRCFGDEYYGTVEQEKPQFEEEEGL--
E--DDWNWDTWAGTEQA-GA------WD---QELHCEDPDFNMDADYDPSQPR-------
---------KKP---------------REAPQTGKKKRK--------SPFAAAVGQE---
--KPVFEPG-DKTFEEYLDEYYRLDYEDIIDDLPCRFKYRTVVPCDFGLSTEEILAADDK
ELNRWCSLKKTC----MYRSEQEELQDKRAYIQKAQNLWKKRQIFKSLCP---EEMETLS
EAT--GKPQRDKDGPQ-----------------------------GQLLAPDGASG----
KQAQPGS--PP----------------APE---EAGPMSHTQKP-VPQRRRR-SKKARLL
GPTVTLGGREFSRQRLQAFGLNPKRLHFRQLGRQRRKPQGPKSGP-------------

------------------------------------------------------------
----------------------------------------------------------EF
DPQQECDF--YRTLSLLKKKDPRIYQKDATFYQAAASSS-----E-SEGEPAAA----EK
PNKVQPMYLKDYERKVVLEKEGKYVDEDSDGDVAHQRRQQ-----T-MSQSYVE------
--EQKQLKERGGSFRAFVED-SGDEASAGEGGSGLLRRRA-QTTEEKAREEASYVEWLKG
QEEVENPEALKEL------------AHLREYWNNPELDEGERFLRDYILNKRYEEEGEEE
EEE----------EDEEGAPGPPAQLAVDDSSDEGELFLKKQEDFEHKYNFRFEEPGAAV
VKTYPRTIASSVRRKDERRKEKREETRERKRREKA---KKQEELKQLKNLKRREILAKLE
KLRQVTGNET--LGLEEQDLEDDFDPDQHDQLMQGCVRVELHGARENAGRCFPGLGI---
----QYVLNKQQ--------------GR--QRLPFARPPPHAVGPSLSSFGAY-QAGRPP
DACVDEPLGRGYPRDRPAGAGSGSLEPNGEPHGGGERRG---------GLDARVL-----
-----------ADQKHFGDEYYGSTEQEK-----PQFAEEE----GLEGGVGEPRG

PF05178 // ENSGT00390000005605_0_Domain_2 (717, 766)

ADDK
ELNRWCSLKKTC----MYRSEQEELRDQRAYSQKAQDARRKRQVFRSLCPERTEAP---A
EAARKPQGGRASPQRQ-------------------------------LPRPDGARGKQ--
----P----RPE---------------RPPAQEEGAPAS-PTGEPAPPGRRR-ARKARVL
GPTVTLGGREFSRQRLRAFGLNPRRLHFRQRARRRAKLRGPKGGP-------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------MYLKDYERKVILEKAGKYVDEENSDGETSNHRLQ-----ETSSQSYVE------
--EQKQLK---ESFRAFVED-SEDEDSAGEGGSSLLQKRA-KTRQEKAQEEADYIEWLKG
QKEIRNPESLKEL------------THLKEYWNDPELDEGERFLRDYILNKRYEEEEDE-
--------E-EKEEEEEGVPGPPVQLAVDDSSDDGELFLKKQEDFEQKYNFRFEEPDSTS
VKTYPRSIASSVRRKDERRKEKREETRERKKREKA---KKQEELKQLKNLKRKEILAKLE
KLRKVTGNET--LG

PF05178 // ENSGT00390000005605_0_Domain_1 (495, 767)

LEEGDLEDDFDPAQHDQLMQKCFGDEYYGAVEEEKPQFEEEE----
GLEDDWNWDTWDGPEQE-GD------WS--QQELHCEDPNFNMDADYDPSQAR-------
---------K-K---------------REAPSTGKKKRK--------SPFAAAVGQD---
--KPVFEPG-DKTFEEYLDEYYRLDYEDIIDDLPCRFKYRTVVPCDFGLSTEEILAADDK
ELNRWCSLKKTC----MYRSEQEELRDKRAYSQKAQNSWKKRQVFKSLCREE--AE-MPA
EAT--GKPQRDGAGPQ-----------------------------KQLPALDGAGG----
KRPRPES--PP----------------AQE---EEAPVSPHKKP-APQRRRR-AKKARLL
GPTVMLGGREFSRQRLQAFGLNPKRLYFRQLGQQRRKQQGPKNSS-------------

------------------------------------------------------MGHRAA
MPEPRGSSQLRVNTAFAARYNRYREREELQRLKDRYGDRDS--GSDSSSESDSSDERVEF
DPQQERDF--YKTLSLLKKKDPRIYQKDATFYNRTA------SSSDSEEEPAAS----EK
QKKVRPMYLKDYERKVILEKAGKYVDEENSDGETSNHRLQ-----ETSSQSYVE------
--EQKQLK---ESFRAFVED-SEDEDSAGEGGSSLLQKRA-KTRQEKAQEEADYIEWLKG
QKEIRNPESLKEL------------THLKEYWNDPELDEGERFLRDYILNKRYEEEEDEE
ED-E----E-EKEEEEEGVPGPPVQLAVDDSSDEGELFLKKQEDFKQKYNFRFEEPDSTS
VSRPTHAASR------------PPAGRRRGTRLGT--

PF05178 // ENSGT00390000005605_0_Domain_0 (458, 541)

-KKQEELKQLKNLKRKEILAKLE
KLRKVTGNDT--LGLEEGDLEDDFDPAQHDQLMQKCFGDEYYGAVEEEKPQFEEEE----

ENSGT00390000005605_0_Linker_0_2 (541, 672)

GLEGTG---LGTGDWQE-GD------WS--QQELHCEDPNFNVGVTGWGSPRG-------
---------PD-----------------GGPLDG---------------------QEE-P
GSLALSRAG-D

PF12936 // ENSGT00390000005605_0_Domain_2 (672, 762)

KTFEEYLEEYYRLDYEDIIDDLPCRFKYRTVVPCDFGLSTEEILAADDK
ELNRWCSLKKTC----MYRSEQEELRDKRAYSQKAQNSWKKRQVFKSLCREE--AE-MPA
EAT--GKPQRDGAGPQ-----------------------------RQLPGLDGAGG----
KRPRPES--PP----------------AQE---EEAPVSPHKKP-APQRRRR-AKKARLL
GPTVMLGGREFSRQRLQAFGLNPKRLYFRQLGRQRRKQQGPKNSS-------------

------------------------------------------------------------
---------------FAARYGRYREREELQRLKDRYGDRDG--GAGSSSESDSSDDRVEF
DPQQDRDF--YRTLSLLKKKDPRIYQKDATFYQRTGSPL----SSESEEKPAAS-----E
KKQVRPMYLKDYERKVILEKGGKYVDEENSDGENSDQRLQ-----QISSQSYME------
--EQKQLR---ESFRPFVED-SEDEDSAGEGGSGLLQKRR-KTREEKAQEDADYVEWLKG
QKETQNPEALKEL------------RPLKEYWDNPGLDEGEQFLRDYILNKRYEEEED--
-----------DDEEEEGIPGSPVQLAVDDSSDEGELFLKKQEDFEHKYNFRFEEPDAAS
VRTYPRSIASSVRRRDERRKEKRGETR

PF05178 // ENSGT00390000005605_0_Domain_0 (448, 514)

ERKKREKA---RKQEELKQLKNLKRKEILAKLE
KLRRVTGNET--LGLGEQDLEGDFDPTQHEQLM

ENSGT00390000005605_0_Linker_0_2 (514, 673)

QVRPPGDTRSSGAL--VTLAVLPE---
-ETEDWNWDTWGGPEQD-GL------WS--QQEPHCEDPDFNMDADYDPSRPQ-------
---------KKR---------------LEAPSTGRKKHK--------SPFAAAVGQR---
--KPVFDPA-DK

PF12936 // ENSGT00390000005605_0_Domain_2 (673, 763)

TFGEYLDEYYGLDYEDIIDDLPCRFKYRRVVPCDFGLSTEEILLADDK
ELNRWCSLKKTC----MYRSEQEELQDKRAYTQKAQNSQKKQQIFKSLCPEDME---TGT
GAP--GKAQRRTTGPQ-----------------------------EQLLAPEGGNW----
KRPQPES--PP----------------AQE---EEAPVSPHKTP-APQKRWR-STKARLL
GPTVTLSGHEFSRQRLQAFGLNPKRLHFRQLGRQRRRHQGRKGCP-------------

------------------------------------------------------VGWRAA
MPEPRGSSPLRVNAAFAARYGRYREREELQRLKDRYGDRHS--SSDSSSESDSSDEHVEF
DPQQERDF--YRTLSLLKKKDPRIYQKDATFYQRTASS-----SDS-EEEPAAE-----K
RKKVQPMYLKDYERKVILEKGGKYVDEENSDGETSNQRLQ-----QSSSKSYVE------
--EQKQLK---ESFRAFVED-SEDEDSAEEGGSGLLQKRA-KSKEEKAQEDADYIEWLKG
QKEIQNPDTLKEL------------THLREFWNNPELDEGERFLRDYILNKRYEEEGEEE
DE-E------EEDEEEERVPGPPVQLAVDDSSDEGELFLKKQEDFELKYNFRFEEPDSAS
VKTYPRSIASSVRRKDERRKEKREETRERKKREKA---RKQEELKQLKNLKRKEILAKLE
RLRQVTGNET--LG

PF05178 // ENSGT00390000005605_0_Domain_1 (495, 767)

FEEQDLEGDFDPARHDQLMQKCFGDEYYGAMEEEKPQFEEEEGL--
E--DDWNWDTWAGPEQG-GA------WS--QQEPHCEDPDFNMDADYDPSQPR-------
---------KKQ---------------REAPSLGKKKRK--------SPFATAVGQE---
--KPVFDPG-DKTFEEYLDEYYRLDYEDIIDDLPCRFKYRTVVPCDFGLSTEEILAADDK
ELNRWCSLKKTC----MYRSEQEELQDKRVYSQKARNVWKKQQIFKSLCPEEAE--M-PT
EAT--GKPQRDRAGSS-----------------------------GQLVAPDGACG----
KRSQPES--TP----------------AEE---EADPVTPTEKL-APQRRKR-GKKARLL
GPTVTLGGREFSRQRLQAFGLNPKRLHFRQLGRQRRKQQGPKSSH-------------

------------------------------------------------------VGRRAA
MPEPRAASPLRVNSAFAARYGRYREREELQRLKDRYGDRDS--GDDSSSESDSSDERVEF
DPQQERDF--YRTLSLLKKKDPRIYQKDATFYQRTAS------SSESEEEPAAS----ET
RKRARPMYLKDYERKVILEKEGKYVDEENSDSETSDQRFQVGGVEQTSSQSYVE------
--EQKQLK---DGFRAFVED-SEDEDSAGEGGSGLLQKRA-KTREEKAQEEADYMEWLKG
HKELQNPESLEEL------------THLKEYWNDPELEEGERFLRDYILNKRYEEEGDDE
EE-E----EDEEEEEE--KGDARVQLAVDDSSDEGELFLKKQEDFEHKYNFRFEEPDSAS
VKTYPRSIASSVRRKDERRKEKRELTR

PF05178 // ENSGT00390000005605_0_Domain_0 (448, 586)

ERKKREKA---KKREELKQLKNLKGKEILAKLE
KLRKVTGNDT--LGFEEGDLEDDFDPARHDQLMQKCFGDEYYGAPGQAPG----CRW---
-GLDDWNWDTWDGPDQD-GA------WS--RQEPHCEDPDFNMDA

ENSGT00390000005605_0_Linker_0_2 (586, 672)

DYDPSQQR-------
---------KKK---------------REAPSLGKKKRK--------SPFATAVGQE---
--KPVFDPG-D

PF12936 // ENSGT00390000005605_0_Domain_2 (672, 762)

KTFEEYLDEYYRLDYEDIIDDLPCRFKYRTVVPCDFGLSTEEILAADDK
ELNRWCSLKKTC----MYRSEQEELQDKRAYSQKAQNSWKKQQIFKSLCPET----ETPT
EAT--GKPQRDKAVPR-----------------------------EQLPVSDGACG----
KRPRPES--PP----------------AQE---EEAPVSPTQKP-APQRRKR-GKKARLL
GPTVTLSGREFSRQRLQAFGLNPRRLHFRQLGRQQRKQQRPKGGS-------------

------------------------------------------------------------
------------------------------------------------------------
--------------------------MAVSFGGLTA------SSSDSQEEPAAL----EK
QKKVRPMYLKDYERKVMLEKAGKYVDEENSDGETSNHRLQ-----ETSSQSYVE------
--EQKQLK---ESFRAFVED-SEDEDSAGEGGSSLLQKRA-KTRQEKAQEEADYIEWLKG
QKEIRNPDSLKEL------------THLKEYWNDPELDEGERFLRDYILNKRYEEEEEEE
ED-E----E-E-KEEEEGVPGPPVQLAVDDSSDEGELFLKKQEDFEQKYNFRFEEPDSAS
VKTYPRSIASSVRRKDERRKEKREETRERKKREKA---KKQEELKQLKNLKRKEILAKLE
KLRKVTGNET--LG

PF05178 // ENSGT00390000005605_0_Domain_1 (495, 767)

LEEGDLEDDFDPAQHDQLMQKCFGDEYYGAVEEDKPQFEEEE----
GLEDDWNWDTWDGPEQE-GD------WS--QQELHCEDPNFNMDADYDPSQPR-------
---------KKK---------------REAPSMGKKKRK--------SPFAAAVGQE---
--KPVFEPG-DKTFEEYLDEYYRLDYEDIIDDLPCRFKYRTVVPCDFGLSTEEILAADDK
ELNRWCSLKKTC----MYRSEQEELRDKRAYSQKAQNSWKKRQVFKSLCREE--AE-TPA
EAT--GKPQRDEAGPQ-----------------------------RQLPALDGAGR----
KRPRPES--PP-----------------AQ---EEAPVSPHKKP-APQRRRR-AKKARLL
GPTVMLGGREFSRQRLQAFGLNPKRLHFRQLGRQRRKQQGPKNSS-------------