Query Results 

-----------MGRKWTYCVVY----TIIQIQFFRGVWEELFNVGD-DVYALPGSDINLT
CQT-KEK-NFLVQMQWSKVTDK-NDMIALYHPQYGLYCGQ--EH----------ACESQV
A-----A--TETEKGVTNWTLYLRNISSALGGKYECIFTLYPEGIKTTVYNLIVEP-Y--
--TQDEHNYTIEIET

PF00047 // ENSGT00390000003446_Domain_1 (196, 301)

NRTLEIPCFQNTSSEIPPRFTFSWLV-------------------
--EKDGVEEVLFT------HHHHVNNSTSFKGRIRLGGDYRLHLSPVQIQDDGRTFSCHL
TVNPLKAWKMSTTVKVFAKPEILMTVENSTMDVLG-ERVFTCLLKNVFPKANITWFIDGR
FLQGNEE-----------------------------------------------------
---GIYITNEEKNCSSGFWELKSVLTRMHS-GPSQSNNMTAWCMALSPG--PRNKMWNTS
SQPITVSFDSVIAPTKHLP-TVTG--STLGTQPFSDAGVSPT--GYLATPSV-TIV----
---DENGLTPDATPQTSNSS-------MTTKDGNYLEAS-SGTDAKNSSR-AAA-SSKSG
SWPFPFTSPP---EW------HSLPGTSTGPQEP-DSPVSWIPSEVHTS-APLDASLAP-
HDTIIST---TTEFPNVLTTANGT-------------T---KIDHGP------ITSII--
---VNQPSDGMSWPVLVAALLFFCTLLFGLGVRKWYRYQNEIMER----PPPFKPPPPPI
KYTYIQEPIGCDLCCHEMEVL-------

-----------MGRKWTYCAVY----SIIQIQFFRGVWEETFNAEE-A

PF07686 // ENSGT00390000003446_Domain_0 (49, 172)

IYAPPGSDVNLT
CQI-KET-DFLVQMQWSKVTDK-TDVIVVYHPQYGFHCVP--GH----------TCESQV
A-----S--LETRENVIKWTLHLRNVSTTFSGKYECSFTVYPDGIQTTVHS

ENSGT00390000003446_Linker_0_1 (172, 189)

LLVAP-V--
--IQDEHN

PF00047 // ENSGT00390000003446_Domain_1 (189, 303)

HTIDTETNQTLEIPCFQNTSSEISPGFTFEWLV-------------------
--KKDGVQEVLFT------HNDHINYSASFKGRVKLGADSGLHLSPVQIQDDGKTFTCRL
TV

ENSGT00390000003446_Linker_1_2 (303, 336)

NPLEVWKTSTIVKVFAKPEILLIVENSTVDVLR

PF08205 // ENSGT00390000003446_Domain_2 (336, 474)

-ERAFTCLLKNVFPRANITWLIDGK
FLQGDEQ-----------------------------------------------------
---GIHITNDEKNDRSGFRELKSVLTWTHSKRPAQSNSMTIQCKALSPG--PRNKMWSTS
SQAIMLPSDLVTATKEYLA-RMTG--STLGTKPFPDDNVSPT--RSPAMSSM-TIV----
---DGDVATPDATSQGSNSS-------MTTKGFNYSQTS-IGTDANASRA--A--SSDRG
SWPTPSISPA---EW------LSLPGTSPGPQEP-DAPVSWIPSERHTS-TPSEASLAP-
QDVITST---TNKLPDVPITAKGT-------------T---ENEYSH------ITNIT--
---ISKPRDGMSWPVVVAALLSFCTILFGLAVRKWCQYQKEIMER----PPPFKPPPPPI
KYTCIQEPPGHDLPCREMEAL-------

-----------MGRKWTYCAVY----SIIQIQFFRGIWEERVNAGE-TIYF

PF07686 // ENSGT00390000003446_Domain_0 (52, 174)

APGSDVNLT
CQTTKEK-EFLIQAQWSKVTDK-NDPIVVYHPQYGFHYAQ--GH----------AHGAQV
A-----F--IKIQRNVTEWTLSLKNISTTFSGQYECSFTVYPEGIQTTVYNLIVAP-L--
--TQEEHNYTIETETNWTLEIPCFQNTSSEISPGFTFSWLV-------------------
--EKDGVQEVLLT------HDDHICNSTSFKGRVKLGADFGLHLSPVQIQDDGLTFSCQL
RVTPLEVWKTSTTVKVFAKPEILMMMENGTMDVLG-ERVFTCLLKKVFPRANITWLIDGR
FLQRNEE-----------------------------------------------------
---GIYITNDKKTDRSGFWEVKSVLTRMHGNRPAQSNNVTVQCMALSSG--PRNKMWNIS
SQVIMLPSDLVNVPTEHLT-SVTG--STLGTQPFPNDNVSPT--RYPGMSSM-AIV----
---GGDVSTPDATPQASNSS-------MTTKGFNYVQTS-SGTDSKNSSR-AA--SSSSA
SWPSPSVSPP---EW------LSSPGTSTKPLQP-DAPDSLVPSEIHTS-VPSEASLAP-
HDVISST---TRRFPDVATTARGM-------------T---KNDHNY------ITSIT--
---VNKPRDGMSWPVVVAALLLFCAILFMLGVRKWCQYQKEIMER----PPPFKPPPPPI
KYTCIQETTGHDLPCHEMETL-------

-----------MEKKWKYCAVY----YIIQIHFVKGVWEQTFNTGE-NI

PF07686 // ENSGT00390000003446_Domain_0 (50, 169)

YAPLGSDVNLT
CQTQKT--GILVQIQWSKVTDK-ADLIALYHPQYGFHCAH--GT----------PCESLV
T-----F--TETPKNVSKCTLHLRNVSSSVSGKYECMITVYPQGIQTTIYNLLIQTRVTP
--GEWKINHTIEIEINRTLEIPCFQNSSSEISSEFTYAWLV-------------------
--EYNRTQETLIT------QDHLISNSTLFKDRVKLGTDYRLHLSPVQIFDDGRKFSCHI
RVSPDKILRSSTTVKVFAKPEIPVIVENNSTDVLV-ERTFTCSLNNVFPKANITWFIDGS
FLHNEKE-----------------------------------------------------
---GIYITNEERKGRDGFLELKSVLTRVHSNQPAQSDNLTIWCMALFPV--PGNKVWNIS
SEKITFSLGSENSPTDPPL-SVTE--STLDTLPSPASSVSPT--RYPATSSV-TLG----
---DVSASKPNSTPQSSNSS-------VTTRGFGYPQTS-SGTEAKKS------------
--------------------------------------VSRIPHETHSS-SPSGAGSTLH
DNVFTST---ARAFSEVPTTANGS-------------M---KTNHIH------ITGIV--
---ANKPKDGMSWPVITAALLFCCVVLFGLGVRKWCQYQKEIMER----PPPFKPPPPPI
KYTCIQEPNESDLPCHEMETL-------

-----------MEKTWKYCAVY----YIIQIHFVKGVWGKPFNTEE-NIYATLGSDVNLT
CQTQAI--GFLVQMQWSKVTDK-ADLIALYHPQYGFHCAY--GS----------PCESLV
T-----F--TETPENGSKWTLHLRNMSSSVSGRYECMLTLYPEGMQTKIYNLLIQTH---
--DHWRGRHHVYTFCGWK------------ISSLLIVTLLLSSESDENSTDSWVLLSKGK
RYEDNGTQQTLIS------QDHLISSSTLLKDRVKVGTDYRLHLSPVQIFDDGRKFSCHI
RVGRDKILRSSTTVKVFAKPEIPMIVENNSTDVLV-

PF08205 // ENSGT00390000003446_Domain_2 (337, 449)

ERTFTCLLKNAFPKANIIWFIDGS
LLHDEKE-----------------------------------------------------
---GIYITNEERKGKDGFLELKSVLTRVHSNKPAQSDNLTIWCMALSPV--PGNKVWNTS
SEKITFLLGSEMSTTDPPP-TVTE--STLDTQPSPASSVSPT--RYPAMSSV-TLV----
---DVSALRPNTTSQSSSSS-------VTTRDFNYPWTS-SGTDAKKS------------
--------------------------------------FSRIPSETYSS-STSGAGSTFH
DNVFTRT---TRAFSEVPTTANGS-------------T---KTNHVH------ITGIV--
---VSKPKDGMSWPVIVAALLFCCIILFGLGVRKWCQYQKEIMER----PPPFKPPPPPI
KYTCIQEPNESDLPYHEMETL-------

-----------MEKKWTFCAVY----SIIQIHFVRGVWEEIVNTRE-DVYALPGSDVELT
CHIQKK--DFLVQMQWSKVTDK-VDMIAIYHPQHGFYCAH--GI----------PCESLV
A-----F--TEAPGKVTNWTLFLRNVSSSVGGNYECSFTMFPEGIQTKTYNLLVQRHVTQ
--DKWRSNHTIETEMNQTLKIPCFQNSSAEISSEFTVAWLV-------------------
--EVNGTQETLAS------QKH-INKSVIFKDRVKIDSHHGLHLSPVQIQDDGLKFSCCV
KGRYGEILRSSTTVKVFAKPETPMIMENNSMGFLG

PF08205 // ENSGT00390000003446_Domain_2 (336, 463)

-ERTFTCSLKNVFPKAKLTWFIDER
SLQDGNE-----------------------------------------------------
---VLYITNQQHMHKETQKSHLSTLQIVHGNQLAQSNNLTIVCGSVSG---PENKVWTIS
EKITIFLGDSVAPSVDATF-SVTE--STNSISPTRSSSLIPL--CYPATSSM-TPM----
---DMPSST---TSQT---SNSH----VATQDISYSRTS-SGIEAGKS------------
--------------------------------------ISWTSSETYSS-SSSNTGSTLH
GDVFTST---SRTFSEVPTTARGS-------------T---KNNRIY------ITGIE--
---LGRPEDGISWPVIVAFLLFFCVILFGLGIRKWCQYQKEIMER----PPPFKPPPPPI
KYTCIQEPIGSDLPYQEMETL-------

-----------MGRKWTYCAVY----SIIQIQFFRGVWEETFNAEE-AIYAPPGSDVNLT
CQI-KET-DFLVQMQWSKVTDK-TDVIVVYHPQYGFHCVP--GH----------TCESQV
A-----S--LETRENVIKWTLHLRNVSTTFSGKYECSFTVYPDGIQTTVHSLLVAP-V--
--IQDEHN

PF00047 // ENSGT00390000003446_Domain_1 (189, 303)

HTIDTETNQTLEIPCFQNTSSEISPGFTFEWLV-------------------
--KKDGVQEVLFT------HNDHINYSASFKGRVKLGADSGLHLSPVQIQDDGKTFTCRL
TV

ENSGT00390000003446_Linker_1_2 (303, 336)

NPLEVWKTSTIVKVFAKPEILLIVENSTVDVLR

PF08205 // ENSGT00390000003446_Domain_2 (336, 474)

-ERAFTCLLKNVFPRANITWLIDGK
FLQGDEQ-----------------------------------------------------
---GIHITNDEKNDRSGFRELKSVLTWTHSKRPAQSNSMTIQCKALSPG--PRNKMWSTS
SQAIMLPSDLVTATKEYLA-RMTG--STLGTKPFPDDNVSPT--RSPAMSSM-TIV----
---DGDVATPDATSQGSNSS-------MTTKGFNYSQTS-IGTDAKMVEA--A--SSDRG
SWPTPSISPA---EW------LSLPGTSPGPQEP-DAPVSWIPSERHTS-TPSEASLAP-
QDVITST---TNKLPDVPITAKGT-------------T---ENEYSH------ITNIT--
---ISKPRDGMSWPVVVAALLSFCTILFGLAVRKWCQYQKEIMER----PPPFKPPPPPI
KYTCIQEPPGHDLPCREMEAL-------

-----------MEKKWTYCAVY----SIIQIHFIRGIWGKTVNT-E-DIYARPGSDVNLT
CQTRKI--SFLVQMQWSKVTDK-ADLIALYHPQHGFYCAH--GS----------PCESLV
A-----F--TETSRNVSKWTLHLRNISSSVSGKYECIFTLYPEGIQTKIYNLHVQTHDTQ
--NKWGPNHTIEIEVNQTLEIPCFQNISLEIASEFTFAWLV-------------------
---DNGTQETLFT------QDHLVSNSTLFKDRVKLGTDYRLHLSPVQIPDDGLKFSCEI
VVRPDKTLRSITKVKVFAKPEISMIVEKNFTD

PF08205 // ENSGT00390000003446_Domain_2 (333, 472)

ALK-ERTFTCSLKNVFPEANLTWFIDGR
FLQDEEE-----------------------------------------------------
---GISIVNKESKGKRGFLELESVLTRVL-NKPAQSNNLTIWCMALSPA--PGNKVWNIS
SEKITLSLGSANPPTGSPS-SDTE--STLVTQPSPASSVSPT--RYPITSSM-ALI----
---DASTSKPNATPQSSISS-------VTTQGFNVSWTS-SGTDGKKL------------
--------------------------------------ISWIPNETFSS-SSSSTSSTLH
DDVFTST---TRVFSEVPTTVNRS-------------T---KNNHVH------ITGIV--
---VNKHKDGTSWPVIVAALLFFCVVLFSLGVRKWCQYQKEIMER----PPPFKPPPPPI
KYTCIQESSGSDLPCHEMETL-------

-----------MEKTWTYCAVY----SIIQIHFIRGVWEETFNAGE-DVYALPGSDVNLT
CQTQNT--GYLVQTQWSRVTSK-VDLIALYHPQYGFYCAH--GR----------PCESQV
A-----F--RETPEKVLQWTLHLRNMSSSLSGKYECSFTLYPRGIQNKIYNLLLQTHGIQ
--EEWGGNHTIEIEINQTLEMPCFQNISSEISSEFTFAWLV-------------------
--ENNATLETLFS------QDHLISNSTLFKDRVKLSADYRLHLSPVRIFDDGRKFFCYI
RVRPGKILKSSTRVKVFAKPEIPMIMENN

PF08205 // ENSGT00390000003446_Domain_2 (330, 450)

SVDVSR-ERTFTCSLKNVFPKANLTWFMDGR
FLQDENE-----------------------------------------------------
---GIYVTNEERKGEGGLLEVTSVLTRVHENNPAQSDNLTIWCMAMSPG--PGNKVWNIS
SEKITFSLGSVNPPTDSPQ-SITE--SILGTQPSPANSVSPT--KHPTASSL-ALE----
---DKSTTRPNTMTQTSNSS-------VTTEAFNYTRTS-NGTDAKKWKS-SQT-LDNNG
---LWCHK-H---PFNSHHVGYSLVCTAEFFNDL-TLTASWIPTVAYSA-SPSGTGSTLY
DDVFTST---RAAFSEVLTTTNGS-------------T---KKIHIY------VTVWV--
---VKKPKDGMSWPVIVAALLFPCMVLFGLGVRKWCQYQKEIMER----PPPFKPPPPPI
KYTCIQEPMGSDLPCHEMETL-------

-----------MEKKWKYCAVY----YIIQIHFVKGVWGKPLNT

PF07686 // ENSGT00390000003446_Domain_0 (45, 172)

EE-NIYATLGSDVNLT
CQTQAK--GFLVQMQWSKVTDK-ADLIALYHPQYGFHCAY--GS----------PCESLV
T-----F--TQTPENGSKWTLHLRNMSSSVSGRYECMLTLYPEGMQTKIYNLLIQTHVTP
--DEWKSNHTIEIEINQTLEIPCFQNSSSEISSEFTYAW---LVVKNSSTDSWVLLSKGK
RYEDNGTQQTLIS------QDHLISSSTLLKDRVKVGTDYRLHLSPVQIFDDGRKFSCHI
RVGPDKILRSSTTIKVFAKPEIPMIVENNSTDVLV-ERIFTCLLTNVFPKANIIWFIDGS
FLHDEKE-----------------------------------------------------
---GIYITNEERKGKDGFLELKSVLTRVHSDKPAQSDNLTIWCMALSPV--PGNKVWNIS
SEKITFLLGSEMSTTDPPP-SVTE--STLDTQPSPASSVSPT--RYPATSSV-TLA----
---DVSALRPNTTPQSSSSS-------VTTQDFNYPWTS-SGTDAKKS------------
--------------------------------------FSQIPSETYSL-SPSGAGSTLH
DNVFTST---TRALSEVPTTANGS-------------T---KTNHVH------ITGIV--
---VSKPKDGMSWPVIVAALLFCCMILFGLGVRKWCQYQKEIMER----PPPFKPPPPPI
KYTCIQEPNESDPPYHEMETL-------

-----------MEKRWPSCVF----CLFILTHHVDGQLEGTIIKTE-AVHALPGSDVTLM
CSILNGNSISVTQTQWSKVDDTPPSRIAVSHPVYGITKTHH--------------CWADF
NQTSISHDARANPVECYQWILHLSNVSLSLTGRYECSFATYPYGTQVAEINLIINSHIVS
FSEDEKHYVVA

PF07686 // ENSGT00390000003446_Domain_1 (192, 316)

EVLLNQTLEIPCFENITSVNWSKYPLKWLI-------------------
--AENGHEETTLTIKEFYHQDVSKTINLLYKERIQLGANNELKISPVKINDDNKVFSCYV
KYHPERILASTTKVK

ENSGT00390000003446_Linker_1_2 (316, 336)

VFAKPEISIALQNRSNGTVG

PF07654 // ENSGT00390000003446_Domain_2 (336, 467)

-EASLTCIVRKAFPKPNLTWYADGE
ILNDQLE-----------------------------------------------------
---ETSVEAENLKDGEGLYELRSILKIQSTNQ--SSTNQTFWCMCSFPF--LGNKTWNIS
SEEIIVSSGKLSSLSPSLVFTRIIQNLQSSKL--PSVSSTSL--TF--------------
--TSPVTSKPVSTAQSKYYSGSFLCL---------------------------------R
-YFLYCCTDL------R------KMGMKKSVQQTTLITFS--SSEPHHGH---GVER---
NGQFDST----TDIVRYTNATASSE---------------SETSQPH-----INGSTK--
---VKPENVHFSWPAVVAILLLLCSFLILLGIRKWCLYQKEIMNR----PPSFKPPPPPI
KYASMIESDGTTQSCHELETL-------

-----------MEKKWTYYAVC----SIIQIQFVRGIWEDISDESE-NIYALPGSDVDLT
CQLQKK--SQLVQTQWSKVTDK-MDLIAIYHDQHGFYCAN--MS----------PCESLV
T-----F--LQTPWNVTKWILHLRNISSSLTGKYKCSFTLFPDGIRTRTYNV-IQVPVIQ
--DEWRNNYTIEIEINQTLEIPCFQNISSEILSALTFTWLV-------------------
--EDNGTQETIIS------QNHHISNATSFADRVTLDTSYRLHLFPVQIQDDGRKFSCHV
GVKSGKIFKSSTTVKVFAKPEIPKIMENKTTDVLG-

PF08205 // ENSGT00390000003446_Domain_2 (337, 463)

KSIFTCSLKNVFPKANLTWFIDGR
ILQSDKE-----------------------------------------------------
---ELYITTEERKDKSGFLELKSVLTKMHHTTPVQSNNLTIWCTALFRV--PGNKVRNTA
SEKITFSLGSVNFPTEAAF-SVTA--STLGTQPSPTNSESLT--RYPATSSV-VLI----
---DVTTSKPHILPQTSSAS-------MTKQDVSESWTS-SDTDTKKS------------
--------------------------------------VSWIPSETYSL-STLGAGSTLH
DDVFTST---IGDISEILTTANRL-------------T---KNNTIH------ITVTK--
---SKKSKDGMSWPVIVAALLSFCVVLLGFGVRKWCQYQREIMER----PPPFKPPPPPI
KYTYIQEPMGSDLPCHEMETL-------

-----------MEKKWTYCAVY----SIIQIHFARXXXXXXXXXXX-XXXXXXXXXXXXX
XXXXXXX-XXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXX--XX----------XXX-XX
X-----X--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMR
--DEWGSDHTIEIEMNQTL-IPCFQNISSEISTEFTFAWLVEDSN----IDC-VHLYESI
KXXXXXXXXXXXX------XXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXKPEISMIVENSSMDVLG-

PF08205 // ENSGT00390000003446_Domain_2 (337, 431)

EKTFTCSLRNVFPKANLTWYIDGM
VFQGEEE-----------------------------------------------------
---GTNITNEERKGKGKFLELKSVLTRVHGNKPTKS-NLTIWCMALSPA--PGNKVWNVS
SEKITFSFGSVNLPTDPPL-SVSE--STFSTHPSSANSETPT--RYPVTTSM-ALV----
---DVSTSRPDDASPTSNFN-------VTTQGFSSSWTS-SGTDPQKS------------
--------------------------------------VSEIPSKTYSS-SPSRASSTLD
DEVFTST---TRALSEVLTTANGS-------------T---KRNRIV------ITGTV--
---INKPKDGMSWPVIVAALLFFCMVSFGIGVRKWCQYQKEIMER----PPPFKPPPPPI
KYTCIQEPIGSDLPCHEMETL-------

-----------MEKKWTLCAVY-----IIQIQLVRGIQEDISSGRE-NMYALPGSDINLT
CQLQKR--SYLVQAQWSKVTHK-LDPIAIYHPQHGFHCTN--AS----------SCESLV
T-----F--LQTPRGVTKWTLHLRNISSSLSGKYKCSFTLYPDGIRTRTYNLLIPAPVTQ
--NEWRNNHTIEIQINQTLEIPCFQNISSEILSEFTFAWLV-------------------
--GDNGTQETIIT------QGQHISNATSFTDRVTLGADYRLKLFPVQTHDDGRKFSCHV
GVKPGKILKSSTVVKVFAKPETPMITENKTTDVLG-

PF08205 // ENSGT00390000003446_Domain_2 (337, 463)

KSIFTCSLKKVFPKANISWFIDGQ
FLQGDKE-----------------------------------------------------
---ELQITNEEKKNKSGFLELKSILTKMHSNKPAQSNNLTVWCMASFPV--PGNKAWNTS
SEKITVSLGSVNLPTGSPL-SVTE--STLGTQPSPANSASPT-SKNIFTCF--FLH----
---KLLILSPNR-------R-------LK-----------------KK------------
--------------------------------------KK---------------LQPAH
YEILDKL---ITY-LNVQPLSHAL-----------------NPREII------CSSFP--
---DAKTKDGMSWPVMVAALLAFCVVLFGLGLRKWCQYLREIMER----PPPFKPPPPPI
EYTCIHEPMGSDLPCHEMETL-------

-----------MEKKWTYCAVC----SIIQIHFVKGVWGKAPNA

PF13895 // ENSGT00390000003446_Domain_0 (45, 173)

-E-DTYAFPGSDVNLT
CQTEKK--GFLVQMQWSKVTDK-LDLIALYHPKYGLHCAN--GG----------PCESLV
T-----Y--VETPRNVSIWTLHLRNMSSSLTGKYECTFTLYPEGARTKIYNLLIQTNVTQ
--DEWRSSHIMEVWINQTLEIPCFQNISSEILSESTFAWLVQ------------------
--EGNGIQEIRIT------QGHAISNSTLFKDRVKLGVDYTLCLSPVQIHDDDRKFSCHI
MVRPGKILRNSITVKVFAKPEISMIVENNSTDVLG-ERTFTCSLRNVFPTANLTWFTKGG
FPRGEKK-------GPKWSGLRKTR-------SKHKRPDFMTRNSTKRLKNSWSGNIHTE
TSSEIYIINEKRKDKSGFLELKSVLTRVFGNKPAQSQNLTIWCTALSPA--PGNKVWNIS
SEKITFSLGSVKPSADPPL-EGVT--STLGTQPSPVNSVSPT--RYPAVTST-ALE----
---DVGASTPNTTPQTSNSS-------VTTQGFNYSWTS-NGKDTT--------------
------------------------------------NSASWMPNETYSS-SSSGASSTIH
GDVFTST---ARTFSEVPTTANGS-------------T---KNIHIH------ITGIS--
---VNKPKDGMSWPVIVAALLSFCVALFGLGVRKWCQYQKEIMER----PPPFKPPPPPV
KYTCIQESIGSDLPCHELETL-------

-----------MERKWTYCAVY----SIIQIHFVRGILEETLNAEE-DIYALPGSDVSLT
CQTRKK--GFLVQMQWSKVTDK-VDLIALYHPEHGFYCGS--RS----------RCESLV
A-----F--RVTPGSVSQWTLHLRNMSSSLTGKYECSFTLYPEGIQTKIYNLFIQTNVTQ
--DEWRSNHTVEIEI

PF00047 // ENSGT00390000003446_Domain_1 (196, 300)

NQTLEIPCFQNISLEISSKLTFAWLV----EDSITD--SILYVGI
K-EDSGTQETLIT------RDHPISNSTLFKDRVKLGTDYALYLSPVQIHDDDRKFSCHV
EVRPGRILRSFTTVKVFAKPETPMIGENNSMDVFG-ERTFTCSLRNVFPTANLTWFIERS
LPQGERE-----------------------------------------------------
---EMHITNEERKDRGGFLELKSVLTYVYDSKPAQLNNLTIWCMALSPV--PGNKVWNNS
SEKITFSLGPENPPTEPLL-SVVE--STVGTQPSLANSISPT--XXXXXXXX-XXX----
---XXXXXXXXXXXXXSNSN-------VTTRGFSYSETS-SGKDVKYL------------
--------------------------------------ASWMPSETYSS-SASSAGSTLH
GDVFSST---TRAFSEVPTTANGS-------------T---KNNDIH------ITGIM--
---VNKPKDGMSWPVIVAALLFSCLVLFGLGVRKWCQYQKEIMER----PPPFKPPPPPI
KYTCIQESIGSDLPCHEMETL-------

-----------MGRKWTYCVVY----AIIQIQFFRGAWEELFNAGDNNVY

PF07686 // ENSGT00390000003446_Domain_0 (51, 170)

ALPGSDVNLT
CQT-MEK-DLMVQMQWSKVTDE-IDMIVVYHPQYGFHYMQ--GV----------ACESRV
A-----A--VETLKDATKWTLNLRNISSSLSGKYECSFTMYPTGTKTIVYNLIVEP-Y--
--TQDEHNRTIEIETNRTLEIPCFQNTSSEISPRFTFSWLV-------------------
--EKDGVEDVLFT------YDYHVSNSTAFKGRVGLGADYGLRLSPVQIQDDGRTFSCFL
RISPLKVWKTSTTVKVFAKPEILMTVENTTMDVLG

PF08205 // ENSGT00390000003446_Domain_2 (336, 472)

-ERVFTCLLKNVFPKASITWLIDGR
LFQGNEE-----------------------------------------------------
---GIYITNEEKNSSSGFWELKSVLTRMHN-RTSQSNNMTVWCMALSPG--PGNKMWNTS
SQPITFSLDSGTAPTKRLP-NVTG--STLGAQTFPDAEVSPT--RYLATSSM-TIV----
---DENVLTPDPTPQTSNSS-------MTTKDVNYSQPS-SGTDAKNSSR-AAS-SSDGG
SRPFPSTSPP---KW------LSLPHTSTGPQEP-DSAVSWIPTDAYTS-GSSDASLTS-
HDVIIRT---TKEFPDVLTTANGT-------------T---KIKHGH------VTGIT--
---VNKPRDGMSWPVAVATLLFFCILLFGLGVRKWCQYQKEIMER----PPPFKPPPPPI
KYMCIQEPTGRGMPCHEMEVL-------

-----------MGRKWTYCAVY----SIIQIQFFRGVWEEIFKAGE-AIYAPPGSDVNLT
CRT-KEK-DFLVQMQWSKVTDT-IDLIVVYHPQYGFHCAP--RH----------TCESQV
A-----S--IETGKNVTKWTLHLRNVSTTFSGKYECSFTVYPGGIQTTVHSLIVAP-V--
--IQEER

PF07686 // ENSGT00390000003446_Domain_1 (188, 316)

NHTIETETNQTLEIPCFQNTSSEISPGFTFEWLV-------------------
--KKDGVQEVLFP------HNDHISNSTSFKGRVKLGADSGLHLSPVQIQDDGKTFSCRL
TVNPLKIWKTSTTVKVFAKPEILLIVENSTMDGLG-QRAFTCLLKNVFPRANITWLIDGK
FLQGDEE-----------------------------------------------------
---GIFITNDEENDRNGFQELKSVLTRTHGNRPAHSNNVTIQCKALSPG--PRNKMWSTS
SQAITLSLDSVTVPMEYLS-SVTG--STLGTQTFPDGSVSPT--RFPVMSSM-AIV----
---DGDVTTPDATPQGSNSS-------TTTQGFNYSQIS-SETDAKNASR-AA--SLGGR
SLPSPSISPE---EW------LLLPGTSP------NAPISLIPSERHTL-APSEASLAP-
HDVITST---TKEFPDVPTTARGT-------------I---ENEHSH------ITNIT--
---ISKPRDGMSWPVVVAALLSFCTILFGLGVRKWCQYQKEIMER----PPPFKPPPPPI
KYTCIQEPPGCDLPCREMEAL-------

----------------------------MAHVFFSGVWGKGLNAGE-DVYAVPGSDVNMT
CQIQLK--GLLVQMQWSKITDK-INLIALRHSQYGVHWAH--GH----------SCKSAV
D-----F--RQIPENITIWTLLLRNVSSSLSGKYECSFTLFPEGIWTKTYNLLIQTPVTQ
--DEWSSNHTIEIEINQTLEIPCFQNNSSEISPEFTFTWLV-------------------
--EDNGAQETLIQ-------DHHNSSSTFFKDRVKLCADHRLCLSPVQIHDEGRKFSCQV
RLRPGKILRSSTTVKVFAKPEIPMIVENSTMNVLG-

PF08205 // ENSGT00390000003446_Domain_2 (337, 446)

ERTFTCSLKNVFPKASLTWFIDGR
FLQGEEK-----------------------------------------------------
---GINITNEERKGKNGFLELKSTLTRMHGSEPTQSNNLTIWCMALSPV--PGNKMWNTS
SEKITFSLGSVNAPTTEPLPSVTD--SPLSTPPSPANSVSPT--SYPATFSV-ILV----
---DGSTLTSRATPQTRNSS-------VTTQGFNSSSTS-SGIDTEKS------------
--------------------------------------VSWIPSETYSS-SPSGAGSTLH
DDVFTST-STTGEFSEAPTSANGS-------------T---NNSHIH------ITSIV--
---VTKPTGGMSWPVIIAALLFFCMALFGLGVRKWCQYQKEIMER----PPPFKPPPPPI
KYTCIQEPIGNDLPCHEMETL-------

-----------MEKKWMYGVIY----SFMQIHLIWGLLKGRFDERN-VIYATPGTDVNLT
CQLEKR--SLLVQTQWSKITNN-TEIIGLYHPLYGYNCGV--RT----------SCESLV
S-----F--TVLSPNVSEWTLYLRNVSAALSGKYECSFTLFPEGTLTKIQNLLVQNEVAQ
--DEKGGNYTVEALFNHILEIPCFQNISSVISSGITVAWMMEK-----------------
----NGK-Q-----------ETLIQNSTFLKNRSILLKDHELYLPSVETFDDDRKFSCHI
IMQSGKILKNVTRIKVFAK

PF08205 // ENSGT00390000003446_Domain_2 (320, 447)

PEISMNMQNSSTDTLEEQKKFSCLVKNIFPTANLSWYIDGE
LLQNEKE-----------------------------------------------------
---GIHITIEKRKSDEGFYELTSKLRVLKPNQPILPNNLTVWCMTLFPV--PGNEVWNIS
SRKIVFSFSEL-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------

MLILLINLHLKMEMRWLVWAYYFILNHFILMHLISGQSEIIIKKEE-

PF07686 // ENSGT00390000003446_Domain_0 (48, 174)

YVYALPGDDVTLT
CSILKGKGVHVTQTQWSKVDAASQRNIGVYNPRYGTVYTDRGYNYSINFRKSFQYCQTDF
SH-SL---SSTNHMECDQWILQMRNVSLEQSGLYECSFATYPAGTTSSEINLV

ENSGT00390000003446_Linker_0_1 (174, 193)

VMKS---
---DDK-NFVVE

PF07686 // ENSGT00390000003446_Domain_1 (193, 306)

TLLNQTLEIPCLKDMPSENLTNASLNWFL-------------------
--KENKNEELLIS-KQSYYGHEYITRPTSFKERIKMNQENTLIISPVSVFDDGTKFICSV
VYQPG

ENSGT00390000003446_Linker_1_2 (306, 319)

RMIRSTTVMKVFV

PF08205 // ENSGT00390000003446_Domain_2 (319, 467)

KPEISITLNENFR---G-KANFTCMVRKAFPKPKLLWYIGGE
ILKDKSE-----------------------------------------------------
---GIFMENEEPKVAGGFFEMRSLLTIWSTTQ--LPINQSFKCISVYRF--PGNQTQNVS
SEEVLSYGLQKTV--KSIKPSRQV---------TPVLESSTI--RT--LSTGRVAE----
--KST-------------------------------------------------------
--LTIPDHSFTAKNWLN------STGNLSTERV---------------------------
--------------VEQ-------------------TTVSSSDNSPTLKGRFNTNGTT--
---TSPKHTNFSWPAVVAALLSFCTFFIILGIRKWCQYQKEIMNR----PPSFKPPPPPI
KYTSMPIARVP-----------------

------------------------------------------------VHALPGTDVTLL
CTFPKPQSTYIVQAQWSKTDANHLSRIAVHHPILGTHYFEF--------------LEACS
NF-SVSF---SMRKCCNWWALHLRNVTISLSGQYECSFATYPYGTKAAKIQLIIKA

PF07686 // ENSGT00390000003446_Domain_1 (177, 317)

EGKL
-DNHS---LVNEAQLSQTLEIPCLENATSANLSNYPLKWVV-------------------
--EENGKKEELIT-KEPSHPEVYGYGSMLYKWRVHLGLNNALKIFPTKITDDGKVFSCHV
VYHPERIRKSSTTVRV

ENSGT00390000003446_Linker_1_2 (317, 320)

FAY

PF08205 // ENSGT00390000003446_Domain_2 (320, 476)

PEISASLQEGPAGTSQ-KPNVSCIVRKAFPKPSIVWYVDQA
RLTEQSE-----------------------------------------------------
---EMSVEQEDSQDSDGFYQLRSMLMLQETHQ--A--HTTFSCVCLFPF--LRNETRNIS
SEEIFLSFAKTTSKPKGLQPLKC---LMEGAMQVPPADHAP---ARPRITTGMCIIRPMA
IKTSPDFTTRASLAHASTTQGEYLHMKPGAKGRNRDCSS-SEIK--------------SG
-LFL-GCTPH---PLKQ------RPGWQQGTKTLTAS-----KEDSRELI---SATE---
TKSYTSI----TAFTENVTTAYLNDSTTESPKNLKNVTLSSEDTTPV-------HSNV--
---KNIVASRFPWPTVVAVMLLFCSFLIVLGIRKWCQYQKEIMNR----PPSFKPPPPPI
KYTSMVESDGTPPSYHELENL-------

-----------MEKKWTYCAVY----SIIQIHFIRGLWEETFSAGE-DIYALPGSDVNLT
CQTQKK--GFLVQMQWSKISDT-TDLIALYHPQYGFYCAN--GN----------PCESLV
A-----F--AEAPGNVSKWTLHLRNMSSSLSGKYKCSFTLYPEGIWTKIYNLLIQPNVIQ
--DEWRTNQTIEVEINRTLEIPCFQNISLEISSEFTFAWLVXXXXXXXX-----XXXXXX
XXEDNGTQKTLIA------QDQSIRNSTWFKDRVMLGTNYGLYLSPIQIHDDDRKFSCHA
VFRPGKIWTSSTTVKVFAKPEIP

PF08205 // ENSGT00390000003446_Domain_2 (324, 434)

MTVENNSMDVLG-ERTFTCSLRNVFPTANLTWFIDGG
SLQGEKK-----------------------------------------------------
---EIYIVNEERKDKGGFLELKSVLTKIHISEPAQSTNLTIWCMALSPG--PGNKVWKIS
SEKISISLGSVTPPSHPSP-NRTD--STHSTQSSPADGISPT--XXXASSSV-GVE----
-----VSASTPNAPQTNNSI-------VTTHSFNYPWTS-SEKDVKQS------------
--------------------------------------VSWMPSETHSS-SPSGDITRI-
----------SRAFSEISTTANES-------------T---KNSDFH------ITSTV--
---ANMPKDGVSWPVIVAALLFLCLVIFGLGVRKWCEYQKEIMER----PPPFKPPPPPI
KYTCIQEPIGSDLPCHEMETL-------

-----------MEKKWTFCAVY----SIIQIHFVSGIWEEKYNED--VVYALAGSD-NLT
CQIPKT--DHLVXXXXXXXXXX-XXXXXXXXXXXXXXXXX--XX----------XXXXXX
X-----X--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXAQ
--EEWRSSHTIEINLNQTLKIPCFQNISAET-SELAVAWSVTDNSTG----S----YLPF
FGEVNGTQETLIS------QERPNSTSALFKDRVKLHADHGLYLSPVQIQDDDRKFSCQV
RLSSGKMATSSTTVKVFAKPEK

PF08205 // ENSGT00390000003446_Domain_2 (323, 428)

PVIMENNSLSFWG-ERTFTCLLKNVFPKANLTWFIDGR
SLEAEKE-----------------------------------------------------
---GIYITKWRAN-------VKDKLFKLHGNQSAQANNLTIWCEALSSA--PDNNVYNLS
SEKITFSWDSTTSPADTTF-SVTE--ST--------NSIAPT--GYPATSSK-TPL----
---DMSASTI------SHTSNSH----VTTQDISYSWTS-SGTDAKKXXX-XXX-XXX--
-----------------------------------------------XXXXXXXXXXXXX
XGIFTST---TRPFTEVPTTASGS-------------T---KNNHTH------ITGVV--
---IDRPKHGMSWPAIVAVLLFFCISLFGLGIRKWCQYQKEIIER----PPPFKPPPPPV
KYTCIQESIGYGLPCHEMEPLW------

-----------MERKWKYCAVY----YIIQIHFVKGVWGKPFNTEE-N

PF07686 // ENSGT00390000003446_Domain_0 (49, 161)

IYATVGSNVNLT
CQTQAK--GFLVQMQWSKVTDK-ADLIALYHPQYGFHCAY--GS----------PCESLV
T-----F--TQTPENGSKWTLHLRNMSSSVSGKYECMLTLYPEGMQTKIYNLLIQTHVTP
--DEWKSNHTIEIEINQTLEIPCFQNSSSEISSEFTYAW---LV-ENSSTDSWVLLSKGK
RYEDNGTQQTLIS------QDHLISSSTLLKDRVKVGTDYRLHLSPVQIFDDGRKFSCHI
RVGPDKILRSSTTIKVFAKPEIPMIVENNSTDVLV-ERTFTCLLKNVFPKANIIWFIDGS
FLHDEKE-----------------------------------------------------
---GIYITNEERKGKDGFLQLKSVLTRVHSNKPAQSDNLTIWCMALSPV--PGNKVWNIS
SEKITFLLGSEMSTTDPPL-SVTE--STLDTQPSPASSVSPTKIRYPATSSV-TLV----
---DVSALRPNTTPQSSSSS-------VTTRDFNYPWTS-SGTDAKKT------------
--------------------------------------FSQIPSETYSS-SPSGAGSTLH
DNVFTST---TRAFSEVPTTANGS-------------T---KTNHVH------ITGIV--
---VSKPKDGMSWPVIVAALLFCCMILFGLGVRKWCQYQKEIMER----PPPFKPPPPPI
KYTCIQEPNESDLPYHEMETL-------

------------------------------------------------VHALPGTDVTLV
CMFPKLHSTHIIQTQWSKTNGSSSAKIAVHHPTYGTHYFHF--------------SEAPY
NI-SVSF---SRRSAIEWWALHLENVTVSLSGQYECTFATYPYGTKAAKIQLTVKAEVKE
----ERH-YLKKVWLKQTLEIPCLEDVTSENLSTYPLKWLV-------------------
--GENGRKEELVT-KEPSCPAVYRNSSLLHGQRLLLGLNNTLKVFPTKITDDGRVFSCHV
LQHPERVQKSSTTVRVFALPEI

PF08205 // ENSGT00390000003446_Domain_2 (323, 469)

SISLQEGSASTLQ-KPSVSCVVRKAFPKPRLLWYMDRA
ILTEQPA-----------------------------------------------------
---EISVVQEDLQDSEGFYELRSTLMLQGTHE--T--HKAFSCVCLFPS--PGNETRNIS
SEEIFVSFVSVGSLLDHCPNVMH---TESEVLPFPSSKTETL--AWLTAEQQSCLSKGT-
--ESPSISTEK----------------FTTKAINIQCEE-RGFSSLNYTFSLAEQVAWEA
-IFLLTSGPNVCQSWHD------NPGQKTGKKERGDSEYTSEPAEAHRHI---PVAS---
QGHWAAK----TVIS----TIIL-------VLGCSNTSHYVNKIKPL-------TSDR--
---RNTKASRFPWPTVVAVLLLSCSFLVALGIRKWCQYQKEIMSR----PPSFKPPPPPI
KYTSMVEPDGTPPSCHELENL-------

-----------MEKGWTYGMIY----SVIQIHLVWGLVKATSDGKN-VIYASPGTDVKLM
CEVQKT--SSLVQTQWSKLTNS-TEMIALYHPQHGYHCNA--RT----------ACTSLV
T-----F--TKISPNVSEWILHLRNVSAAANGKYECSFTLFPDGIWTKVLNLLIQTEVAQ
--EERGGNYTAEVLFNHTLEIPCFRNISSVASSGITFAWLMVSIILFSG----KILY--S
QQEENGMQE-----------TRIIQNNTFPDNRIILRKDHALYLSPIEILDNNRKFSCHV
TIHSGKILKNVTRITVFAKPEISMDMQNSST

PF08205 // ENSGT00390000003446_Domain_2 (332, 447)

DILE-EKNFSCLVRNVFPTANLSWYIDGE
LLQDQKE-----------------------------------------------------
---GIDMTTEKRNRDEGFYELTSMLRVLKPNQSIVPNNLTVWCMTLFPV--PGNEVWNIS
SRKITFSFGYVNTPTDSSN--FTE--STFSAFTSSLSSTGTA-AGKKTSTSI-FSK----
---NTSIVEPEFEPRSSNSSANI----FPTS-SNFALSS---------------------
------------------------------------NSVFHLPSETGKK-TATIPGMCSH
LGIRVSPLRTSSELPAGTTTANLF-------------T---ENDYSH------VTSTL--
---PNKSEGGMSWPVIVASLLFICFFLFGLGVRKWCQYLKEIMER----PPPFKPPPPPI
KYTCIGEAVGDDLPCHEMETL-------

-----------MGRKWTYCAVY----SIIQIQLFRGVWEEILNARK-SVYAPPGSDVNLT
CQT--QK-GFLVQMQWSKVTDK-VELIAIYHPQHGFHCPH--GH----------PCESHV
A-----S--IETPGNATKWTLHLRNVSSTLSGKYECSFTLYPEGIQNTVYNLLVQAPAPQ
--DEWGRNYTIEIE

PF07686 // ENSGT00390000003446_Domain_1 (195, 316)

INQTLEIPCFQNTSSETSCGFTFEWLV-------------------
--DSNGTQEALIT------HNHQVSNSTLFKDRVKLGADCGLHLYPVQIHDDGRIFSCHL
GVSSLKVWKTSTTVKVFAKPEGPMIVENTTMDVLG-ERRFTCLVRNVFPKANIKWLVGGR
FLQGDEE-----------------------------------------------------
---GIQITNEKKKDRSGFWELKSILTKMYGNRLAPS-NVTVLCMALSSG--PGNKTWKTS
SEIITLSLDSENSSTEQPP-VVTE--STPSTQLFPDNSSSPR--RNPIMSST-TFI----
---NVNSSTPHATPQTSRPN-------MSTESFNHFRTF-NGTDAKN-------------
--------------------------------------FSWTLSETYTS-APSDTSFTF-
YDVITST---IRESPKVSTVASEA-------------TK--NNSHIY------ITSIV--
---VNKPRDGMSWPVVIAILLCFCIILFGLGVRKWCQYQKEIMER----PPPFKPPPPPI
KYTCMQEPIGSDLPCHEMEAL-------

-----------MGRKWTHCVVY----AIIQIQFFRGVWEELFNVGD-DVYALPGSDINLT
CQA-KEK-NFLVQMQWSKVTDK-NDMIALYHPQYGLYCGQ--EH----------ACESQV
A-----A--TKTPKGVTNWTLYLRNISSALSGKYECVFTLYPEGIKTTVYNLIVEP-Y--
--TQDEHNH

PF00047 // ENSGT00390000003446_Domain_1 (190, 301)

TIEIETNRTLEIPCFQNTSSEIPPRFTFSWLV-------------------
--EKDGVEEVLFT------HGHHINNSTSFKGRIRLGEDYGLHLSPVQIQDDGRTFSCHL
TVSPLKAWKMSTTVKVFAKPEILLTVENSTMDVLG-EIGFTCLLKNVFPKADITWFIDGR
FLQGNEE-----------------------------------------------------
---GIYITNEEKHCSSGFRELKSVLTRMHS-GPSQSNNMTAWCMALSPG--PRNKMWNTS
SQPITVSFDSVTAPTKHLP-NVTG--STLGTQPFSDAGVSPT--GYLATSSV-TIV----
---DGNVLTKDATPQTSNSS-------MTTKDGNYSEAS-RGTDAKNSSR-AAS-SSKSG
SWPFPSTSPP---EW------HSLPGTSTEPQEP-DSPVSWIPSEVHTS-APLDSSLAP-
HDTIISS---TTEFPDVLTTANGT-------------T---KIDHGP------ITSII--
---VNQPSDGMSWPVLVTALLFFCTLLFGLGVRKWYRYQNEIMER----PPPFKPPPPPI
KYTYIQEPIGCDLCCHEMEVL-------

-----------MEKKWTFCAVC----SIIQIQFVRGIWEDITSERE-NIY

PF07686 // ENSGT00390000003446_Domain_0 (51, 174)

ALPGSDVNLT
CQLEEK--SFLVQMQWSKVTNK-TNLIAVYHPQHGFHCAS--GS----------PCESLV
T-----F--LQTPRNVTKWTLHLRNISSSLSGKYKCSFTLYPDGIRTRTYNLLVQAPVPQ
--DEWRKNRTIEIEINQTLEIPCFQNISSEILSESTFAWLV-------------------
--EDNDTLATVIT------RDHHISNSTSFTDRVKLGADYRLHLSLVQIHDDDRKFSCHV
GVKPGTILKSSTTVKVFAKPEIPMVMENKTVDVLG-

PF08205 // ENSGT00390000003446_Domain_2 (337, 451)

KSIFTCSLNKVFPKANISWIIDGQ
FLQGDKE-----------------------------------------------------
---ELHITNEERKDKNGFLELKSVLKKSHSNKPAQSNNLTIWCIALFPV--PGNKVWNTS
SEKITFSLGSVNIPTDSPF-SVTE--STLGTQPSPTNSAPLT-IGYPAMSSM-VLI----
---DVNTSKPHSVPQTSSSG-------VTHQVSSDSWTS-RDSWTSTG------------
-------------------------------------------------------TDAKK
YDAFTGT---MGGFSKILTTANRL-------------T---ANQTLH------ATDIV--
---VNKPEDGMSWPVIVAALLSSCVLLFGLGLRKWCQYQREIMER----PPPFKPPPPPI
MYTCIQEPLGSDLPCHEMETL-------