Query Results 

MEAPEYLDLD---EIDFSDDISD-QREQGNRIQRRGLGARDREDTLGFGSDRAKMTVVVA
QGAGHCPADEYSVTSLKTIPELC-------------------------------------
----------RRCDSQSEDRS-VSSSSWNCSVSALITNTQKPTGIADVYGKFRPVKRVSP
LKHQPETLENNESDDQKNQK-VEYQKGSDSDPGPQPEELSPGDGDGGP-QSKSTEP-STL
LGELEHYDLDMDEILDVPYIKSSQQLASFTKVTPEKRILGLCTTINGLS-GKACSPGSAE
NSPAAMTPFCVLSPVKSPHLRKAS-SVVREQQKLSAEESESSPPLVKCGS-AYEPENQTK
DFLNKTFNEPPGRKREKAM-PDCQLRAFHPQSSATDPKLEE--QVGGVTWTS-PQGPEER
SEYLKKVKSILNIVKEGQISLLPHLAADNLDKIHDE

PF00023 // ENSGT00390000001485_0_Domain_0 (457, 490)

NGNNLLHVAASQGHAECLQHLTSL
MGEDCLSERNAEKLTPAGLAIKNGQL--ECVRWMVS-ETEAIAELSCSK

PF00023 // ENSGT00390000001485_0_Domain_3 (530, 569)

DFPSLIHYAGC
FGQEK---ILLWLLQFMQEQGISLDEVD

ENSGT00390000001485_0_Linker_3_4 (569, 570)

Q

PF00023 // ENSGT00390000001485_0_Domain_4 (570, 603)

DGNSAVHVA-SQHGYLGCIQTLVEYGANVTM
QNHAGEKPSQSAERHGHTLCSRYLVVVETCMSLASQVVKLTKQLKEQTMERVTLQNQLQQ
LLEAQKSE--SLVSSPSSPSSPASRRSQWKSPDADDESVAKSKPGVQEGIQVLGSLSA--
SGRARAKAKD-EDSDKILR----QL------LGKDISESVC----------TQE--KLSL
EFQDAQA-SSRNGKKIPAEKRELKLARLRQLMQRSLSESDTDSNTSEDPKSTPVRKPDRP
RPQPIVGSVESVDSAESLHLMIKKHT-LASGRRFP-FGIKASKS-LDGHSPSP-TSESSE
PDLESQCPSSGTTPPSQPSGDPIQPSPDSTTAQKVAMSPKSALKSPSSKRRTSQNLKLRV
TFEEPVVQMEQTN-LEVNG--EKDRDKGRTLQKASAN--SESGDQLKRPFGTFRSIMETL
SGNQNNNNNSQAANQLKM-STLPLASLGRKT-TDAKGNPVSSASKGKNKAEM-YGSCVTL
SSNTLTGEPLRNHAWHNDINRKMKKSYSIKHNAEPESKELFL

MEAPEYLDLD---EIDFSDDISD-NRNQGNRISKLGLGARDREDTLGFDSDRTKMTIVDF
--LRHCLENEYSVTSLKTIPELC-------------------------------------
----------RRCDSQNEDRS-VSSSSWNCSVSTLITNVQKPTGIADVYSKFRPVKRVSP
LKHQPETLDNNESDDQKNQK-VEYQKGGDSDPGPQPEELGPGGRESGP-QSRTAGS-NAL
LGELEHYDLDMDEILDVPYIKSSQQLATFTKVTSEKRILGLCTTINGLS-GKACPTGSAE
NSLANMTPFCVLSPVKSPHLRKAS-SVLHDQQKSSPEDCESSPPLVKCGS-AYEPENQSK
DFLNNTFSDPHGRKVEKPV-PDCQLRAFHLQSSAPEPKLEE--QIGGMNWAS-SQGPEER
SEYLKKMKSILNIVKEGQISLLPHLAADNLDKIHDE

PF00023 // ENSGT00390000001485_0_Domain_0 (457, 491)

SGNNLLHIAASQGHAECLQHLTSL
MGEDCLNERNAEKLTPAGLAIKNGQL--ECVRWMVS-ETEAIAELSCSK

PF00023 // ENSGT00390000001485_0_Domain_3 (530, 569)

DFPSLIHYAGC
FGQEK---ILLWLLQFMQEQGISLDEVD

ENSGT00390000001485_0_Linker_3_4 (569, 570)

Q

PF00023 // ENSGT00390000001485_0_Domain_4 (570, 603)

DGNSAVHVA-SQHGYLGCIQTLVEYGANVTM
QNHAGDKPSQSAERHGHTLCSRYLVVVETCMSLASQVVKLTKQLKEQTMEHVTLQSQLQQ
LLEAQKSEGKSLFSSPSSPSSPASRKSQWKSPDTDDESVAKSKPGIQEGMQVLGSLSA--
SSRARAKAKD-EDSDKILR----QL------LGKDISENVC----------TQE--KLSL
EFQDTHA-PNRNSKKIPLEKRELKLARLRQLMQRSLSESDTDSNNSEDPKSTPVRKADRP
RPQPIVESVEGMDSAESLHLMIKKHT-LVSGRRFP-FSIKASKS-LDGHSPSP-TSESSE
PDLESQCPGSGTAPPNQPSGDPTQPSPDSTAAQKVATSPKSALKSPSSKRRTSQNLKLRV
TFEEPVVQMEQTS-PELNG--EKDREKGRTLQRTSTS--SESGDPLKRPFGTFRSIMETL
SGNQNNNNNYQSVNQLKT-STLPLTSLGRKM-TDAKGNPMSSASKGKNKAGM-SSSCINL
SSKVLIEEHLHNYARHNDINREMKKSYSTKHTAEPETKELFL

MEAPEYLDLD---EIDFSDDISG-NRNEGDRLQKLGLRGK----------GQGRLTVVTA
LGAGRCPENEYSVTSLKTIPELC-------------------------------------
----------RRCDSQTDDRS-VSSSSWNCGVSTLITNTQKPTGIADVYSKFRPVKRVSP
LKHQPETLENNENDDQKNQK-VEYQKGDESGPGPQPEEPGPGEGVGGP-PGKSSEP-STS
LGELEHYDLDMDEILDVPYIKSSQQLPSFTKVTSEKRILGLCTTINGLS-GKACSTGSAE
NSPSSMAPFCVLSPVKSPHLRKVS-TVIRDPHKLSTEEPQSSPPLVKCGS-AYEPEN---
----QTFSDPHGRKVEKTM-PDCQLRAFHLQSAPAEPTPEE--QVSGLAWTS-SQVPEER
SEYVKKVKSILNIVKEGQI

PF12796 // ENSGT00390000001485_0_Domain_0 (440, 516)

SLLPHLAADNLDKIHDENGNNLLHIAASQGHAECLQHLTSL
MGEDCLNERNAEKLTPAGLAIKNGQL--ECVRWLV

ENSGT00390000001485_0_Linker_0_3 (516, 533)

S-ETEAIAELSCSKDFP

PF12796 // ENSGT00390000001485_0_Domain_3 (533, 602)

SLIHYAGC
YGQEK---ILLWLLQFMQEQGISLDEVDQDGNSAVHVA-SQHGYLGCIQTLVEYGANVTM
Q

ENSGT00390000001485_0_Linker_3_5 (602, 627)

NHAGEKPSQSAERQGHTLCSRYLVV

PF16700 // ENSGT00390000001485_0_Domain_5 (627, 671)

VETCMSLASQVVKLTKQLKEQTVERVTLQNQLQQ
LLEAQKSEGKSLPSSPSSPSSPASRKSQWKSPDAEDESTAKHKPGVQEGIQVLGSLSA--
SSRARAKTKD-EDSDKILR----QL------LGKEISENVC----------TQE--KLSL
EFQDVQA-SSRNSKKIPLEKRELKLARLRQLMQRSLSESDTDSNNSEDPKNTPVRKADRP
RPQPIVESVESMDSAESLHLMIKKHT-LTSGRRFP-FSIKASKS-LDSHSPSP-TLESSE
PDLESQCAGSGSTPPNQPSGDPTQTSPDSAAAQKVATSPKSALKSPSSKRRTSQNLKLRV
TFEEPVVQMEQPG-PELSG--EKDKERGRIPHRAPVS--SESGDQLKRPFGTFRSIMETL
SGNQNNNNNYQAASQLRT-STLPLTSLGRKT-TDAKGNPASSASKGKNKAEM-YSSCTSL
SSNTLTEERLHNSARHNDINRKMKKSYSIKHVAEPESKELFL

MEAPEYLDLD---EIDFSDDIS--------------------------------------
----------YSITSLKTIPELC-------------------------------------
----------RRCDSQNEDRS-VSSSSWNCGVSTLIGNAQKPTGIADVCNKFRPVKRVSP
LKHQPESSENNESDDQKNQK-GEYQKGSESQPAPPNDDQSPGEGENL--KSKNIEP-TVL
LGELEHYDLDMDEILDVPYIKSSQQLVPFSKVAPEKKILGVCSTVNGVS-GKTCPTGSTE
NSPSGVTQFCVLSPVKGSQLRKTQ-PIVLDQHKHITEELELSQPLVKCSS-VHESEAQGK
GFLCRTFVDPQAHKTEKTM-PNCHLRTFHLQTAVAENKQLEE---LNMNWSS-AGGPEER
NEEVKKFKSILNIVKEGQISLLPHLAADNLDKIHDE

PF00023 // ENSGT00390000001485_0_Domain_0 (457, 490)

CDNNLLHVAASKGHAECLQHLTSL
MGEDCLNER

ENSGT00390000001485_0_Linker_0_1 (490, 492)

NI

PF00023 // ENSGT00390000001485_0_Domain_1 (492, 516)

EQLTPAGLAIKNG--QLECVRWMV

ENSGT00390000001485_0_Linker_1_3 (516, 530)

S-ETEAIAELSCSK

PF00023 // ENSGT00390000001485_0_Domain_3 (530, 569)

DHPSLIHYAGC
YGQEK---ILLWLLQFMQEQGISLDEVD

ENSGT00390000001485_0_Linker_3_4 (569, 570)

Q

PF00023 // ENSGT00390000001485_0_Domain_4 (570, 603)

DGNTAVHIA-AQHGYLGCIQTLVEYGANVTM
QNHVGEKPSQSAERHGHTMCSRYLVVVETCMSLASQVVKLTKQLKEQTVERVTLQNQLQQ
LLEAQRSEGKSLPMSSSSPSSPASGKPQWKPSEADELSPPKSKLNTQDGIQILGSLGTS-
-SRTRAKIKD-EDSDKILR----QL------LGKEISENVC----------TQE--KLTL
EFQDAHA-SSKNVKKILPEKRELKLARLRQLMQRSLSESDTDSANSEDHKNTPVKRTDKP
RPQPIVESVE---STESLHLMIKKHT-SAAGRRFP-FGTRASKS-VDGHSPSP-TSESSD
PDNEAQYQ-SGTVPQSQFCGDSSPSSTDSATAQKVATSPKSALKSPSSKRRTSQNLKLRV
TFEEPVVQVELAE-SELNE--EKDKDRGKALLRAPPSTGEPAGDQLKRPFGTFRSIMETL
SGNQNNNNNCQTANLIKTSSTLPFTSLGRKT-ADSKGNPAA-FTKGRSKPGP-YCSHTSF
SSSTLNEEHLCNYAWHDDIGKKSQKSYSQKSSEEPELQEFFL

MEAPEYLDLD---EIDFSDDIS--------------------------------------
----------YSVTSLKTIPELC-------------------------------------
----------RRCDSQNEDRP-VSSSGWSCGVSTLITNTQKPTGIADIYSKFRPVKRVSP
LKHQPETLENTENDDQKNHK-VEHQKGGGPDP---PEQLRPDDGGRGLPPGKGADP-ASA
PDELEHYDLDMDEILDVPYIKSTQQLASFTKATSEKRILGLCTTINGLP-GKACSTGSNE
NSPPSAAPLCVLSPVKSPHLRKAS-AVLLEKHKPSVEESSSSPPLPPCGS-ACEPESQSK
DFLNKSFSDPPGRKMEKTM-TDCQLRSFHLPSSTTEPRLEE--QVNGLAWPS-SQGSEEK
TEHLKKVKSILNIVKEGQISLLPHLAADNLDKIHDDSGNNLLHIAASQGHAECLQHLTSL
MGEDCLSERNADALTPAGL

PF12796 // ENSGT00390000001485_0_Domain_3 (500, 602)

AIKNGQL--ECVRWMVS-ETEAIAELSCSKDFPSLIHYAGC
YGQEK---ILLWLLQFMQEQGISLDEVDQDGNSAVHVA-SQHGYLGCIQTLVEYGANVTM
Q

ENSGT00390000001485_0_Linker_3_5 (602, 627)

NHAGEKPSQSAERHGHTLCSRYLVV

PF16700 // ENSGT00390000001485_0_Domain_5 (627, 671)

VETCMSLASQVVKLTKQLKEQTVERVTLQKQLQQ
LLEAQKSESKSLPSTPSSPPSPASRTAQWKAADADEESPARSKPAVQEGIQVLGGLSS--
ASRPRPKAKD-EDSDKILR----QL------LGKEISENVC----------TQE--KLSL
EFQDAQA-ASKNSKKIPVEKRELKLARLRQLMQRSLSESDTDSNHSEDPKNTPVRKGDRP
RPQPIVESVESVDSSESLHLMIKKHS-VASGRRFH-FSTKASKS-LDGHSPSP-TSESSE
PDVESQCPAAGRTPPSQPSGEHPQPSPDSTAAQKVATSPKSALKSPSSKRRTSQNSKLRV
TFEEPLVQMEQTS-PELNG--EKEKESGRTLQRSSAA--GEPGEPLKRPFGTFRSIMETL
SGNQNNNNNYQAAHQLKT-STLPLPSLGRKA-PDAKGDPASNASKAKNKAVS-SI-----
------------------------------------------

MEAPEYLDLD---EIDFSDDISY-SVTSLKT-IP--------------------------
---ELC------------------------------------------------------
----------RRCDSQNEDRS-VSSSGWNCGVSTLITNTQKPTGIADVYSKFRPVKRVSP
LKHQPETLENNESDDQ---K-AEYQKGGDPDPGPQPEELGPRAVEGSP-QRKSAEP-STL
LGELEHYDLDMDEILDVPYIKSSQQLASFTKATSEKRILGLCTSINGLS-GKACPTGSAE
SSPSNMTPFCVLSPVKSPHLRKAS-S-VQDQQKLSPEESESSPPPVKCGS-AYEPESQGK
DVLHKTFSDPHSRKVDKAMAPDCQLRAFHLQSSATDPKLEE--QIGGMNWTS-SQGPEER
SEHLKKVKSVLNIVREGQISLLPHLAADNLDKIHDESGNNLLHIAASQGHAECLQHLTSL
MGEDCLNERNVEKLTPAGL

PF12796 // ENSGT00390000001485_0_Domain_3 (500, 602)

AIKNGQL--ECVRWMVS-ETEAIAELSCSKDFPSLIHYAGC
FGQEK---ILLWLLQFMQEQGISLDEVDQDGNSAVHVA-SQHGYLGCIQTLVEYGANVTM
Q

ENSGT00390000001485_0_Linker_3_5 (602, 627)

NHAGEKPSQSAERHGHSLCSRYLVV

PF16700 // ENSGT00390000001485_0_Domain_5 (627, 671)

VETCMSLASQVVKLTKQLKEQTMQRVTLQNQLQQ
LLEAQKSEGKSLLSSPSSPSSPACRKSQWKSPDAEDESVAKSKPGVQEGIQVLGSLSA--
SSRARAKVKD-EDSDKILR----QL------LGKDISENVC----------TQE--KLSL
EFQDAQT-SSRHSKKIPLEKRELKLARLKQLMQRPLSEADTDSNNSEDPKGTPVRKVDRP
RPQPIVESVEGVDSAESLHLMIKKHT-LASGRRFP-FSIKASKS-LEGHSPSP-TSESSE
PDLESQCPGSGNTPSSQPSGEAPQPSPDSAAAQKVATSPKSALKSPSSKRRTSQNSKLRV
TFEEPVVQMEQTS-LELNG--EKEREKGRTLQRTSAG--SESGDQLKRPFGTFRSIMETL
SGNQNNNNNYQASSQLKT-STLPLTSLGRKV-TDGKGNTGSSASKGKNKAEM-YGSCINL
SSNTLIEEHLRNYARHDDISRKMKKSYSIKHVAEPESKELFL

MEAPEYLDLD---EIDFSDDIS--------------------------------------
----------YSVTSLKTIPELC-------------------------------------
----------RRCDSQNEDRS-VSSSSWNCGISTLITNTQKPTGIADVYSKFRPVKRVSP
LKHQPETLENNESDDQKNHK-VEYQKEGDPDQGPQTEELGPEDGVGGL-PGKSSEP-SSA
LGELEHYDLDMDEILDVPYIKSSQQLASFSKVTSEKRILGLCTTINGLS-GKACSTGSTE
NSSSNMTPFCVLSPVKSPHLRKAS-AVLRDPHKLSTGESESSPPPIKCGS-AYEPESQNK
DFLNKAFNDPRNRKIEKTM-PDCQLRAFHVQSSATEPKLDE--QVNGMNWTS-SQGLEER
NEYLKKVKSILNIVKEGQISLLPHLAADNLDKIHDENGNNLLHITASRGHVECLQHLTSL
MGEDCLNERNAEKLTPAGLAIKNGQL--ECVRWMVS-ETEAIAELSCS

PF12796 // ENSGT00390000001485_0_Domain_3 (529, 602)

KDFPSLIHYAGC
YGQEK---ILLWLLQFMQEQGISLDEVDQDGNSAVHVA-SQHGYLGCIQTLVEYGANVTM
Q

ENSGT00390000001485_0_Linker_3_5 (602, 627)

NHVGDKPSQSAERHGHTLCSRYLVV

PF16700 // ENSGT00390000001485_0_Domain_5 (627, 671)

VETCMSLASQVVKLTKQLKEQTVERVTLQNQLQQ
LLEAQKSEGKSLPSSPSSPSSPASRKSQWRVPDIGDESTAKSKLGIQEGIQVLGSLSA--
SSGVRAKTKE-EDSDKILR----QL------LGKEISENVC----------TQE--KLTL
EFQDAQA-CSRHSKKIPLEKRELKLARLRQLMQRSLSESDTDSNNSEDPKNTPVRRADRP
RPQPIVESVESMDSTESLHLMIKKHS-LASGRRFP-FSTKASKS-LDGHSPSP-TSESSE
PDLESQYPGSGNIPPSQPSGDPTQSSPDSTAAQKVATSPKSALKSPSSKRRTSQNSKLRV
TFEEPVVQMEQTG-LELNG--EKDKDKGRTLPRNSTS--SESGEQLKRPFGTFRSIMETL
SGNQNNNNNYQTAIQLKT-STLPLTSLGRKM-TDAKGNPVNSAGKGKTKAEM-YSSCINL
SSNMLIEEHLHNCARHNDINRKMK-KYSIRHIAEPESKELFL

MEAPEYLDLD---EIDFSDDISD-NRNQGYRISLGFLGSRDREDILGFGSVRAKVTVVAT
LGT-------YSVTSLKTIPELC-------------------------------------
----------RRCDSQNEDRS-VSGSSWNCSVSTLITNTQKPTGIADVYSKFRPVKRVSP
LKHQPETLENNESDDQKNQK-AEYQKGGDSDPDPQPEELSPVHGEGGP-QSKSTEP-SAL
LGELEHYDLDMDEILDVPYIKSSQQLASFTKVTSEKRILGLCTTINGLS-GKACSPGSAE
NSPSNMTPFCVLSPVKSPHLRKAS-SVVRDQQKVPTEESESSPSLVKSGS-AYEPENQSK
DFLNKTFSDPHSRKVDKAM-PDCQLRAFHLQSSAAEPKLDE--QIGGMNWTS-SQGPEER
SEYLKKVKSILNIVKEGQISLLPHLAADNLDKIHDE

PF00023 // ENSGT00390000001485_0_Domain_0 (457, 490)

SGNNLLHVAASQGHAECLQHLTSL
MGEDCLSERNFEKLTPAGLAIKNGQL--ECVRWMVS-ETEAIAELSCSK

PF00023 // ENSGT00390000001485_0_Domain_3 (530, 569)

DFPSLIHYAGC
FGQEK---ILLWLLQFMQEQGISLDEVD

ENSGT00390000001485_0_Linker_3_4 (569, 570)

Q

PF00023 // ENSGT00390000001485_0_Domain_4 (570, 603)

AGNSAVHVA-SQHGYLGCIQTLVEYGANVTM
QNHAGEKPSQSAERLGHTLCSRYLVVVETCMSLASQVVKLTKQLKEQTVERVTLQNQLQQ
LLEAQKSEGKSLLSSPSSPSSPASRKSQWKSPDADDESVAKSKPGVQEGIQVLGSLSA--
SSRARAKAKD-EDSDKILR----QL------LGKDISENVC----------TQE--KLSL
EFQDAQA-ASRNSKKIPLEKRELKLARLRQLMQRSLSESDTDSNHSEEPKSTPVRKADRP
RPQPIVESVESIDSAESLHLMIKKHTSVASGRRFP-FSIKANKS-LDGHSPSP-TSESSE
PDLESQCPALGTTPQNQPSGEPTQPSPDSTAAQKVATSPKSALKSPSSKRRTSQNSKLRV
TFEEPVVQMEQTS-LELNG--EKDRDKGRTLQRTSTS--SDSGDQLKRPFGTFRSIMETL
SGNQNNNNNYQAASQLKT-STLPLTSLGRKT-TDSKGHPGSSASKGKNKAEI-YGSCITL
SSNTLIEEHLHNYARHNDINRKMKKSYSIKHIAEPESEELFL

MEAPEYLDLD---EIDFSDDISD-NRSQGNRLQKLGLEDTGREDALG-GSHRAKLTVVAA
LGACHCPENEYSVTSLKTIPELC-------------------------------------
----------RRCDTQNEDRS-VSSSSWNCGISTLITNTQKPTGIADVYSKFRPVKRVSP
LKHQPETLENNESDDQKNQEAVEYQKGGESDPGPQPEDLSPGDGVGGP-PGKSSEP-STS
LGELEHYDLDMDEILDVPYIKSSQQLVSFTKVTSEKRILGLCTTINGLS-GKVCSTGSSE
NSPSNMAPFCVLSPMKSPHLRKAS-AVIRDQHKLSTEEPEISPPLVKCGS-AYEPENQSK
DFLNKTFSDSHGRKVEKTT-PDCQLRAFHLQSSAAESKQEE--QVSSLNWTS-SQSPEER
SEYLKKVKSILNIVKEGQI

PF12796 // ENSGT00390000001485_0_Domain_0 (440, 516)

SLLPHLAADNLDKIHDENGNNLLHIAASQGHAECLQHLTSL
MGEDCLNERNTEKLTPAGLAIKNGQL--ECVRWMV

ENSGT00390000001485_0_Linker_0_3 (516, 532)

S-ETEAIAELSCSKDF

PF12796 // ENSGT00390000001485_0_Domain_3 (532, 602)

PSLIHYAGC
YGQEK---ILLWLLQFMQEQGISLDEVDQDGNSAVHVA-SQHGYLGCIQTLVEYGANVTM
Q

ENSGT00390000001485_0_Linker_3_5 (602, 627)

NHAGEKPSQSAERQGHTLCSRYLVV

PF16700 // ENSGT00390000001485_0_Domain_5 (627, 671)

VETCMSLASQVVKLTKQLKEQTVERVTLQNQLQQ
FLEAQKSEGKSLPSSPSSPSSPASRKSQRKSPDADDDSIPKSKPGVQEGIQVLGSLSA--
SSRARPKAKD-EDSDKILR----QL------LGKEISENVC----------TQE--KLSL
EFQDAQA-SSRNSKKIPLEKRELKLARLRQLMQRSLSESDTDSNNSEDPKNTPVRKADRP
RPQPIVESVESMDSTESLHLMIKKHTLASGGRRFP-FGIKASKS-LDGHSPSP-TSESSE
PDLESQYPGSGSTPPNQPSGDPPQPSPDSTAAQKVATSPKSALKSPSSKRRTSQNLKLRV
TFEEPVVQMEQPS-LELNG--EKDKDKGRTLQRTSTS--NESGDQLKRPFGAFRSIMETL
SGNQNNNNNYQAANQLKT-STLPLTSLGRKT-ADAKGNPASSASKGKNKAEM-YSSCINL
SSNTLIEEHLRNYARHNDINRKMKKSYSIKHIAEPESKELFL

MEAPEYLDLD---EIDFSDDIS--------------------------------------
----------YSVTSLKTIPELC-------------------------------------
----------RRCDSQSEDRP-VSSSSWNCGVSTLITNAQKPTGIADVYSKFRPVKRVSP
LKHQPETLENNESDDQKNQK-AEYQKGGDSDPAPQPEELSPRDGEGSP-QSKSTEP-STL
LGELEHYDLDMDEILDVPYIKSSQQLASFTKVTSEKRILGLCTTINGLS-GKACSAGSAE
NSPSNVTPFCVLSPVKSPYLRKAP-SVVRDQQKLSTEESETSPPLVKCSS-AYESENQSK
DFLNKTFSDPQGHKVDKAT-PDCQLRAFHLQSSAAEPKLDE--QVSGVNWTG-SQGPEER
SEYLKKVKSILNIVKEGQ

PF12796 // ENSGT00390000001485_0_Domain_0 (439, 516)

ISLLPHLAADNLDKIHDENGNNLLHVAASQGHAECLQHLTSL
MGEDCLNERNADKLTPAGLAIKNGQL--ECVRWMV

ENSGT00390000001485_0_Linker_0_3 (516, 529)

S-ETEAIAELSCS

PF12796 // ENSGT00390000001485_0_Domain_3 (529, 602)

KDFPSLIHYAGC
FGQEK---ILLWLLQFMQEQGISLDEVDQDGNSAVHVA-SQHGYLGCIQTLVEYGANVTM
Q

ENSGT00390000001485_0_Linker_3_5 (602, 627)

NHAGEKPSQSAERHGHTLCSRYLVV

PF16700 // ENSGT00390000001485_0_Domain_5 (627, 671)

VETCMSLASQVVKLTKQLKEQTMQRVTLQNQLQH
LLEAQKSEARSLLSSPSSPSSPASRKSQWKSPDTDDESLAKSKPGVQEG-QVLGSLSV--
SSRARAKAKD-EDSDKILR----QL------LGKDISENVC----------TQE--KLSL
EFQDAQA-SSRNSKKIPLEKRELKLARLKQLMQRSMSESDTDSNNSEDPKGTPVRKADRP
RPQPIVESVESVDSAESLHLMIKKHT-LASGRRFP-FGIKASKS-LDGHSPSP-TSESSE
PDLESQCPGSGTTPPNQPPAEPPQPSPDSTAAQKVATSPKSALKSPSSKRRTSQNLKLRV
TFEEPVVQMEQSG-LEQNG--EKDRDKGRPP-RTSAG--NESGDQLKRPFGTFRSIMETL
SGNQNNNNNYQASNQLKT-STLPLT-LGRKT-TDSKGNPGSSAGKGKNKA----------
------------------------------------------

MEAPEYLDLD---EIDFSDDISD-NRSQGNRLQKLGLEDTDREDALGFGSHRAKLTVVAA
LGACHCPENEYSVTSLKTIPELC-------------------------------------
----------RRCDTQNEDRS-VSSSSWNCGISTLITNTQKPTGIADVYSKFRPVKRVSP
LKHQPETLENNESDDQKNQKVVEYQKGGESDLGPQPEELSPGDGVGGP-PGKSSEP-STS
LGELEHYDLDMDEILDVPYIKSSQQLASFTKVTSEKRILGLCTTINGLS-GKACSTGSSE
SSSSNMAPFCVLSPVKSPHLRKAS-AVIRDQHKLATEETEISPPLVKCGS-AYEPENQSK
DFLNKTFSDPHGRKVEKTT-PDCQLRAFHLQSSAAESKPEE--QVSGLNWTS-SQGPEER
SEYLKKVKSILNIVKEGQI

PF12796 // ENSGT00390000001485_0_Domain_0 (440, 516)

SLLPHLAADNLDKIHDENGNNLLHIAASQGHAECLQHLTSL
MGEDCLNERNTEKLTPAGLAIKNGQL--ECVRWMV

ENSGT00390000001485_0_Linker_0_3 (516, 532)

S-ETEAIAELSCSKDF

PF12796 // ENSGT00390000001485_0_Domain_3 (532, 602)

PSLIHYAGC
YGQEK---ILLWLLQFMQEQGISLDEVDQDGNSAVHVA-SQHGYLGCIQTLVEYGANVTM
Q

ENSGT00390000001485_0_Linker_3_5 (602, 627)

NHAGEKPSQSAERQGHTLCSRYLVV

PF16700 // ENSGT00390000001485_0_Domain_5 (627, 671)

VETCMSLASQVVKLTKQLKEQTVERVTLQNQLQQ
FLEAQKSEGKSLPSSPSSPSSPACRKSQWKSPDADDDSVAKSKPGVQEGIQVLGSLSA--
SSRARPKAKD-EDSDKILR----QL------LGKEISENVC----------TQE--KLSL
EFQDAQA-SSRNSKKIPLEKRELKLARLRQLMQRSLSESDTDSNNSEDPKNTPVRKADRP
RPQPIVESVESMDSAESLHLMIKKHTLASGGRRFP-FSIKTSKS-LDGHSPSP-TSESSE
PDLESQYPGSGSTPPNQPSGDPPQPNPDSTAAQKVATSPKSALKSPSSKRRTSQNLKLRV
TFEEPVVQMEQPS-LELNG--EKDKDKGRTLQRTSTS--NESGDQLKRPFGAFRSIMETL
SGNQNNNNNYQAANQLKT-STLPLTSLGRKT-TDAKGNPASSTNKGKNKAEM-YSSCINL
SSNTLIEEHLHNYARHNDINRKMKKSYSIKHIAEPESKELFL

MEAPEYLDLD---EIDFSDDISN-R-FRGNRFRLGTRGREDVL-DFGSDKAKM--TIVTT
LGAGHCPENEYSVTSLKTIPELC-------------------------------------
----------RRCDSQNEDRS-VSSSSWTCGVSTLIT---KPTGIADVYSKFRPVKRVSP
LKHQPETLESNESDDQKNQK-AEYQKGGGSEPAPQPEELSPGDREVGL-PSKSTEP-STL
LGELEHYDLDMDEILDVPYIKSSQQLASLPKGTSEKRILGLCSTINGLA-SKACTQGSTE
SSPSSLAPFCILSPVASPHLRKAS-SLGRDQQKLPDGEPEGSPSAGKCGS-TQEPENQSR
DFLNKTFNDPQSRKGEKAM-PDCQLRSFLVPCSSVDPKTEE--QVGGVKWAS-SQGPEER
SECLKKAKSILNIVKEGQISLLXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXX
XXXEK---ILLWLLQFMQEQGISLDEVDQ

PF00023 // ENSGT00390000001485_0_Domain_4 (570, 603)

DGNSAVHVA-SQHGYLGCIQTLVEYGANVTM
QNQAGEKPSQSAERHGHTLCSRYLVVVETCMSLASQVVKLTKQLKEQTVERVTLQNQLQQ
LLEAQKSEGKSVLSSPSSPSSPVSRKSQWKSPDAEDESIAKSKPGIQEGIQMLGSLAV--
SSRMRIKVKD-EDSDKILR----QL------LGKDISETVC----------TQE--KLSL
EFQDSQA-SSRNAKRIPPEKRELKLARLRQLMQRSLSESDTDSNHSEEPKGTPVRRADRP
RPQPIVEGGESAENTESLHLMIKKHT-LASTRRFP-FGMKASKS-LDGHSPSP-TSESSE
PDSEFQCPGLGNPPPSLSPGEPSQPSPDSSAAQKVATSPKSALKSPSSKRRTSQNLKLRV
TFEEPVVQMEQSN-LELSG--EKEREKSRAPPRASAG--SEAGDQLKRPFGTFRSIMETL
SGNQNNNNNYQAASQLKT-CTLPLTSLGRKAATDAKGQPVSLAGKGKSKAAM-YSSCLNL
PSNPLTEEHLRNYARHNDINRKMKKSYSIKHIAEPESKELFL

MEAPEYLDLD---EIDFSDDISD-NRSQGNRLQKLGLEDTDREDALGFGSHRAKLTVVAA
LGACHCPENEYSVTSLKTIPELC-------------------------------------
----------RRCDTQNEDRS-VSSSSWNCGISTLITNTQKPTGIADVYSKFRPVKRVSP
LKHQPETLENNESDDQKNQKVVEYQKGGESDLGLQPEELSPGDGVGGP-PGKSSEP-STS
LGELEHYDLDMDEILDVPYIKSSQQLASFTKVTSEKRILGLCTTINGLS-GKACSTGSSE
SSSSNMAPFCVLSPVKSPHLRKAS-AVIRDQHKLATEETEISPPLVKCGS-AYEPENQSK
DFLNKTFSDPHGRKVEKTT-PDCQLRAFHLQSSAAESKPEE--QVSGLNWTS-SQGPEER
SEYLKKVKSILNIVKEGQ

PF12796 // ENSGT00390000001485_0_Domain_0 (439, 516)

ISLLPHLAADNLDKIHDENGNNLLHIAASQGHAECLQHLTSL
MGEDCLNERNTEKLTPAGLAIKNGQL--ECVRWMV

ENSGT00390000001485_0_Linker_0_3 (516, 529)

S-ETEAIAELSCS

PF12796 // ENSGT00390000001485_0_Domain_3 (529, 602)

KDFPSLIHYAGC
YGQEK---ILLWLLQFMQEQGISLDEVDQDGNSAVHVA-SQHGYLGCIQTLVEYGANVTM
Q

ENSGT00390000001485_0_Linker_3_5 (602, 627)

NHAGEKPSQSAERQGHTLCSRYLVV

PF16700 // ENSGT00390000001485_0_Domain_5 (627, 672)

VETCMSLASQVVKLTKQLKEQTVERVTLQNQLQQ
FLEAQKSEGKSLPSSPSSPSSPACRKSQWKSPDADDDSVAKSKPGVQEGIQVLGSLSA--
SSRARPKAKD-EDSDKILR----QL------LGKEISENVC----------TQE--KLSL
EFQDAQA-SSRNSKKIPLEKRELKLARLRQLMQRSLSESDTDSNNSEDPKNTPVRKADRP
RPQPIVESVESMDSAESLHLMIKKHTLASGGRRFP-FSIKTSKS-LDGHSPSP-TSESSE
PDLESQYPGSGSTPPNQPSGDPPQPNPDSTAAQKVATSPKSALKSPSSKRRTSQNLKLRV
TFEEPVVQMEQPS-LELNG--EKDKDKGRTLQRTSTS--NESGDQLKRPFGAFRSIMETL
SGNQNNNNNYQAANQLKT-STLPLTSLGRKT-TDAKGNPASSTNKGKNKAEM-YSSCINL
SSNTLIEEHLHNYA----------------------------

MEAPEYLDLD---EIDFSDDIS--------------------------------------
----------YSVTSLKTIPELC-------------------------------------
----------RRCDSQSEDRS-VSSSSWNCNVSALITNTQKPTGIADVYSKFRPVKRVSP
LKHQPETLENNESDDQKNQK-VEYQKGGDPDPGPQPEELSPGDGENGP-QNKSSEP-STL
LGELEHYDLDMDEILDVPYIKSSQQLASFTKVTSDKRILGLCTTINGLS-GKACSPGSAE
SSPSNMTPFCVLSPVKSPHLRKAS-SVIRDQPKLSTEESESSPPLVKCGS-AYEPENQSK
DFLNKTFSDPHGRKREKAT-PDCQLRAFHLQSSATEPKLEE--QIGGGNWTS-SQGPEER
SEYLKKVKSILNI

PF12796 // ENSGT00390000001485_0_Domain_0 (434, 518)

VKEGQISLLPHLAADNLDKIHDESGNNLLHVAASQGHAECLQHLTSL
MGEDCLSERNAEKLTPAGLAIKNGQL--ECVRWMVS-

ENSGT00390000001485_0_Linker_0_3 (518, 536)

ETEAIAELSCSKDFPSLI

PF12796 // ENSGT00390000001485_0_Domain_3 (536, 625)

HYAGC
FGQEK---ILLWLLQFMQEQGISLDEVDQDGNSAVHVA-SQHGYLGCIQTLVEYGANVTM
QNHAGEKPSQSAERHGHTLCSRYLVVVETCMSLASQVVKLTKQLKEQTVERVTLQNQLQQLLEAQKSE--SLLSSPSSPSSPASRRSQWKPPDVDDESVAKGKPGVQEGIQVLGSLSA--SSRARAKVKD-EDSDKILR----QL------LGKDISESVC----------TQE--KLSLEFQDAQA-SSRNSKKIPAEKRELKLARLRQLMQRSLSESDTDSNTSEDPKSTPVRKADRPRPQPIVGSVESVDSAESLHLMIKKHT-SASGRRFP-FGIKASKS-LDGHSPSP-TSESSEPDVEAQCPGSGTTPPSQSPGDPTQPSPDSTAAQKVATSPKSALKSPSSKRRTSQNLKLRVTFEEPVVQMGQPS-LELNG--EKDKDKGRTLQRTSTS--SESGDQLKRPFGTFRSIMETLSGNQNNNNNYQAA

PF12796 // ENSGT00390000001485_0_Domain_4 (536, 625)

HYAGCFGQEK---ILLWLLQFMQEQGISLDEVDQDGNSAVHVA-SQHGYLGCIQTLVEYGANVTMQNHAGEKPSQSAERHGHTLCSRYLVVVETCMSLASQVVKLTKQLKEQTVERVTLQNQLQQ
LLEAQKSE--SLLSSPSSPSSPASRRSQWKPPDVDDESVAKGKPGVQEGIQVLGSLSA--
SSRARAKVKD-EDSDKILR----QL------LGKDISESVC----------TQE--KLSL
EFQDAQA-SSRNSKKIPAEKRELKLARLRQLMQRSLSESDTDSNTSEDPKSTPVRKADRP
RPQPIVGSVESVDSAESLHLMIKKHT-SASGRRFP-FGIKASKS-LDGHSPSP-TSESSE
PDVEAQCPGSGTTPPSQSPGDPTQPSPDSTAAQKVATSPKSALKSPSSKRRTSQNLKLRV
TFEEPVVQMGQPS-LELNG--EKDKDKGRTLQRTSTS--SESGDQLKRPFGTFRSIMETL
SGNQNNNNNYQAANQLKT-STLPLTSLGRKT-TDAKGNPVSSASKGKNKAA---------
------------------------------------------

MEAPEYLDLD---EIDFSDDIS--------------------------------------
----------YSVTSLKTIPALC-------------------------------------
----------RRCDSQNEDRS-VSSSGWNCGVSTLITNPQKPTGIADVYSKFRPVKRVSP
LKHQPETLENNENEDQKNNT-VEYQKGGETDQGPQPEELSPEDGVGGL-PGKGSEP-SQA
LGELEHYDLDMDEILDVPYIKSSQQLAPLTKVTSEKRILGLCTTINGLS-AKTCPIASTE
NSTPNMTPFCVLSPVKSPHLRKAP-TALRDQHKLSTEDSESSPALGKCGP-AYESENHSK
DFLNKVFSDPHSRKIEKSG-PDCKLRSFHLQSSAAGAKTEE--PINGMNWTN-TQGTEER
TEYLKKVRSILNIVNEGQI

PF12796 // ENSGT00390000001485_0_Domain_0 (440, 516)

SLLPHLAADNLDKIHDENGNNLLHIAASKGHAECLQHLTSL
MGEDCLNERNTEQLTPAGLAIKNGQL--ECVRWMV

ENSGT00390000001485_0_Linker_0_3 (516, 529)

S-ETEAIAELSCS

PF12796 // ENSGT00390000001485_0_Domain_3 (529, 602)

KDFPSLIHYAGC
YGQEK---ILLWLLQFMQEQGISLDEVDREGNSAVHVA-SQHGYLGCIQTLVEYGANVTM
Q

ENSGT00390000001485_0_Linker_3_5 (602, 627)

NHAGEKPSQSAERHGHTLCSRYLVV

PF16700 // ENSGT00390000001485_0_Domain_5 (627, 672)

VETCMSLASQVVKLTKQLKEQTVERVTLQSQLQQ
LLEAQKSEGKSLPSSPSSPSSPASTKSQWKALDTDEESTGKSKVGAQEGIQVLGSLSV--
SSRARTKGKD-EDSDKILR----QL------LGKEISENVC----------TQE--KLSL
EFQDAQA-SSRNSKKIPLEKRELKLARLRQLMQRSLSESDTDSNNSEDPKNTPVKRADRP
RPQPIVESVENVDSAESLHLMIKKHS-LASGRRFP-FGMKASKS-LDGHSPSP-TSESSE
PDLDSHGPGLGMTPPTQPSTEATQSISDSTTAQKVATSPKSALKSPSSKRRTSQNSKLRV
TFEEPVVQMEQTG-LELNG--EKDKDKGRAPQRT-----SESGEQMKRPFGTFRSIMESL
SGNQNNNNNYQPASQLKT-CTLPLTSLGRKT-ADAKGNPVNPASKGKNKAAM-YSSCIHL
PSNALVEEHLRDYARHNDIKRNATKTYHMKHTAEPEPRELFL

------------------------------------------------------------
----------YSVTSLKTIPELC-------------------------------------
----------RRCDSQNEDRS-VSSSNWNCGVSTLIANAQKPTGIADVYSKFRPVKRVSP
LKHHPETLENNESDNQKNEK-VEYQKGGAFDNHLP-EELCPGDGE-TL-KSKNLEP-SVL
LGELEHYDLDMDEILDVPYIKSSQQLASFTKAATEKRILGICSTANGLS-VKNSSTGNAE
SLTTGMTPFCVLSPVKSSHLKKGQ-SHVLDQHKHSTEESQLSPPLVTCSS-VHESEIQSK
VFLNKAFADPSMLKVENIMPSSSQLRTLHLQSSATEPKVDE--QNSHGNWN--SGNPEER
SEDMKKIKSILNIVKEGQISLLPHLAADNLDKIHDE

PF00023 // ENSGT00390000001485_0_Domain_0 (457, 491)

SGNNLLHVAASQGHAECLQHLTSL
MGEDCLNERNNDKLTPAGLAIKXXXX--XXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXX
XXXEK---ILLWLLQFMQEQGISLDEVDQ

PF00023 // ENSGT00390000001485_0_Domain_4 (570, 603)

DGNSAVHVT-SQHGYLGCIQTLVEYGANVTM
QNHAGEKPSQSAERHGHTMCSRYLVVVETCMSLASQVVKLTKQLKEQTMERVTLQNQLQQ
LLEAQRSEGKSLLSSPSSPSSPASGKSQWKSTDPDELCITKNKSNTQDGIQVLGSISA--
SNRTKFRAKD-EDSDKILR----QL------LGKEISENVC----------TQE--KLSL
EFQDAQA-SSRNMKKIPPEKRELKLARLRQLMQRSLSESDTDSNNSEDLKNAPVRRTDKP
RPQPIVESVE---SAESLHLMIKKHT-LATGRRFP-FSIRASKS-GDGHSPSP-TSESSD
LDLETQYTTSGSTPQSQSPGDIPQSTPDCTTAQKVATSPKSALKSPSSKRRTSQNLKLRV
TFEEPVVQVEQTD-LEPIG--EKDKDRGKVLPRLPPN--NETSDQLKRPFGTFRSIMETL
SGNQNNNNNYQTVNQSKTSSTLPFTSLGRKT-ADAKGNSVSCVSKGKNKAESHSSSCTNL
SSNLPLEEHLRNYA----------------------------

MEAPEYLDLD---EIDFSDDISD-NRSQGNRLQKLGLEDTDREDAMGFGSHRAKLTVVAA
LGACHCPENEYSVTSLKTIPELC-------------------------------------
----------RRCDTQNEDRS-VSSSSWNCGISTLITNTQKPTGIADVYSKFRPVKRVSP
LKHQPETLENNESDDQKNQKVVEYQKGGESDLGPQPQELGPGDGVGGP-PGKSSEP-STS
LGELEHYDLDMDEILDVPYIKSSQQLASFTKVTSEKRILGLCTTINGLS-GKACSTGSSE
SSSSNMAPFCVLSPVKSPHLRKAS-AVIHDQHKLSTEETEISPPLVKCGS-AYEPENQSK
DFLNKTFSDPHGQKVEKTT-PDCQLRAFHLQSSAAESKPEE--QVSGLNRTS-SQGSEER
SEYLKKVKSILNIVKEGQI

PF12796 // ENSGT00390000001485_0_Domain_0 (440, 516)

SLLPHLAADNLDKIHDENGNNLLHIAASQGHAECLQHLTSL
MGEDCLNERNTEKLTPAGLAIKNGQL--ECVRWMV

ENSGT00390000001485_0_Linker_0_3 (516, 533)

S-ETEAIAELSCSKDFP

PF12796 // ENSGT00390000001485_0_Domain_3 (533, 602)

SLIHYAGC
YGQEK---ILLWLLQFMQEQGISLDEVDQDGNSAVHVA-SQHGYLGCIQTLVEYGANVTM
Q

ENSGT00390000001485_0_Linker_3_5 (602, 627)

NHAGEKPSQSAERQGHTLCSRYLVV

PF16700 // ENSGT00390000001485_0_Domain_5 (627, 671)

VETCMSLASQVVKLTKQLKEQTVERVTLQNQLQQ
FLEAQKSEGKSLPSSPSSPSSPASRKSQWKSPDAEDDSVAKSKPGVQEGIQVLGSLSA--
SSRARPKAKD-EDSDKILR----QL------LGKEISENVC----------TQE--KLSL
EFQDAQA-SSRNSKKIPLEKRELKLARLRQLMQRSLSESDTDSNNSEDPKTTPVRKADRP
RPQPIVESVESMDSAESLHLMIKKHTLASGGRRFP-FSIKASKS-LDGHSPSP-TSESSE
PDLESQYPGSGSIPPNQPSGDPQQPSPDSTAAQKVATSPKSALKSPSSKRRTSQNLKLRV
TFEEPVVQMEQPS-LELNG--EKDKDKGRTLQRTSTS--NESGDQLKRPFGAFRSIMETL
SGNQNNNNNYQAANQLKT-STLPLTSLGRK--TDAKGNPASSASKGKNKAEM-YSSCINL
SSNMLIEEHLRNDTRHNDINRKMKKSYSIKHIAEPESKELFL

MEAPEYLDLD---EIDFSDDIS--------------------------------------
----------YSVTSLKTIPELC-------------------------------------
----------RRCDSQNEDRS-VSSTSWNCGVSTLITNPQKPTGIADVYSKFRPVKRVSP
LKHQPETLENNENDDQKNNT-VEYQKGGETDQSPQPEELSTDDGVRGL-PGKGSQP-SQA
LGELEHYDLDMDEILDVPYIKSSQQLAPFTKVSSEKRILGLCTTINGLS-GKACPIGSSE
NSTPNMTPFCVLSPVKSPHLRKAS-TVLQDQHKLCTENSESLPALGKCAP-AYESENHSK
DFLNKAFSDAHSRKIEKAG-PDCKLRAFHLQSAATGAKPEE--QVNGMNWTN-AQGAEEK
SENLKKVRSILNIVKEGQ

PF12796 // ENSGT00390000001485_0_Domain_0 (439, 516)

ISLLPHLAADNLDKIHDENGNNLLHVAASKGHAECLQHLTSL
MGEDCLNERNAEQLTPAGLAIKNGQL--ECVRWMV

ENSGT00390000001485_0_Linker_0_3 (516, 529)

S-ETEAIAELSCS

PF12796 // ENSGT00390000001485_0_Domain_3 (529, 602)

KDFPSLIHYAGC
YGQEK---ILLWLLQFMQEQGISLDEVDQEGNSAVHVA-SQHGYLGCIQTLVEYGANVTM
Q

ENSGT00390000001485_0_Linker_3_5 (602, 627)

NHAGEKPSQSAERHGHTLCSRYLVV

PF16700 // ENSGT00390000001485_0_Domain_5 (627, 672)

VETCMSLASQVVKLTKQLKEQTVERVTLQSQLQQ
LLEAQKSEGKSLPSSPSSPSSPASRKSQWRILDADDEASGKSKTGAQEGIQVLGSLSA--
SSRARTKGKD-EDSDKILR----QL------LGKEISENVC----------TQE--KLSL
EFQDAQA-SSRNLKKIPLEKRELKLARLRQLMQRSLSESDTDSNNSEDPKNTPVRKADRP
RPQPIVESVETMDSAESLHLMIKKHS-LPSGRRFP-FSTKASKS-LDGHSPSP-TSESSE
PDLDSHCPGSGLTPPTQPSADLTQSSPDSSTAQKVATSPKSALKSPSSKRRTSQNSKLRV
TFEEPVVQMEQTS-LELNG--EKDRDRGRAPQRT-----SESGEQMKRPFGTFRSIMETL
SGNQNNNNNYQPASQLKT-CTLPLTSLGRKT-ADAKGNPVSPASKGRNKPEV-YSSCIHL
PSNMLVEEHLRGYARHNDIKRNTKKTYSRKHDAESESKELFL

MEAPEYLDLD---EIDFSDDISR-NRNEGNRLQKLGLRDK----------GQGRCSVVTA
SGAGRGPENEYSVTSLKTIPELC-------------------------------------
----------RRCDSQTEDRP-VSSSSWNCGVSTLIANTQKPTGIADVYSKFRPVKRVSP
LKHQPETLENNENDDQKNQK-VEYQKGDESGPGPQPQEPGPGDGGGGP-PGKSAEP-STS
LGELEHYDLDMDEILDVPYIKSSQQLPSFAKVTSEKRILGLCTTINGLS-GKACSPGSTE
NSPSSMAPFCVLSPVKSPHLRKVP-TVIRDPHKLSTEEPQSSPPLVKCGS-AYEPEN---
----QTFSDPHGRKVEKTM-PDCQLRAFHLQSAAAEPTAEE--QLSGLAWTS-SQVPEER
SEYVKKVKSILNIVKEGQ

PF12796 // ENSGT00390000001485_0_Domain_0 (439, 516)

ISLLPHLAADNLDKIHDENGNNLLHIAASQGHAECLQHLTSL
MGEDCLNERNAGKLTPAGLAIKNGQL--ECVRWLV

ENSGT00390000001485_0_Linker_0_3 (516, 533)

S-ETEAIAELSCSKDFP

PF12796 // ENSGT00390000001485_0_Domain_3 (533, 602)

SLIHYAGC
YGQEK---ILLWLLQFMQEQGISLDEVDQDGNSAVHVA-SQHGYLGCIQTLVEYGANVTV
Q

ENSGT00390000001485_0_Linker_3_5 (602, 627)

NHAGEKPSQSAERQGHTLCSRYLVV

PF16700 // ENSGT00390000001485_0_Domain_5 (627, 671)

VETCMSLASQVVKLTKQLKEQTVERVTLQNQLQQ
LLEAQKSEGKSLPSSPSSPSSPASRKSQWKSPDADDESVAKHKPGVQEGIQVLGSLSA--
PSRARARAKD-EDSDKILR----QL------LGKEISENVC----------TQE--KLSL
EFQDVQA-SSRNSKKLPLEKRELKLARLRQLMQRSLSESDTDSNNSEDPKNTPVRKADRP
RPQPIVESVESMDSAESLHLMIKKHT-LTSGRRFP-FSIKASKS-LDGHSPSP-TSESSE
PDLESQYAGSGSTPASQASGDPSQTSPDGAAAQKVATSPKSALKSPSSKRRTSQNLKLRV
TFEEPVVQMEQPG-LELSG--EKDKDRGRIPHRASAG--SESGDQLKRPFGTFRSIMETL
SGNQNNNNNYQAASQLKT-STLPLTSLGRKT-TDAKGNPASSASKGKNKAEM-YSSCINL
SSNTLTGERLHNSARHNDINRKMKKSCSIKHIAEPESKELFL

MEAPEYLDLD---EIDFSDDISD-NRSQGNRLQKLGLEDTDREDALGFGSHRAKLTVVAA
LGACHCPENEYSVTSLKTIPELC-------------------------------------
----------RRCDTQNEDRS-VSSSSWNCGISTLITNTQKPTGIADVYSKFRPVKRVSP
LKHQPETLENNESDDQKNQKVVEYQKGGESDLGPQPEELSPGDGVGGP-PGKSSEP-STS
LGELEHYDLDMDEILDVPYIKSSQQLASFTKVTSEKRILGLCTTINGLS-GKACSTGSSE
SSSSNMAPFCVLSPVKSPHLRKAS-AVIRDQHKLATEETEISPPLVKCGS-AYEPENQSK
DFLNKTFSDPHGRKVEKTT-PDCQLRAFHLQSSAAESKPEE--QVSGLNWTS-SQGPEER
SEYLKKVKSILNIVKEGQI

PF12796 // ENSGT00390000001485_0_Domain_0 (440, 516)

SLLPHLAADNLDKIHDENGNNLLHIAASQGHAECLQHLTSL
MGEDCLNERNTEKLTPAGLAIKNGQL--ECVRWMV

ENSGT00390000001485_0_Linker_0_3 (516, 532)

S-ETEAIAELSCSKDF

PF12796 // ENSGT00390000001485_0_Domain_3 (532, 602)

PSLIHYAGC
YGQEK---ILLWLLQFMQEQGISLDEVDQDGNSAVHVA-SQHGYLGCIQTLVEYGANVTM
Q

ENSGT00390000001485_0_Linker_3_5 (602, 627)

NHAGEKPSQSAERQGHTLCSRYLVV

PF16700 // ENSGT00390000001485_0_Domain_5 (627, 671)

VETCMSLASQVVKLTKQLKEQTVERVTLQNQLQQ
FLEAQKSEGKSLPSSPSSPSSPACRKSQWKSPDADDDSVAKSKPGVQEGIQVLGSLSA--
SSRARPKAKD-EDSDKILR----QL------LGKEISENVC----------TQE--KLSL
EFQDAQA-SSRNSKKIPLEKRELKLARLRQLMQRSLSESDTDSNNSEDPKNTPVRKADRP
RPQPIVESVESMDSAESLHLMIKKHTLASGGRRFP-FSIKTSKS-LDGHSPSP-TSESSE
PDLESQYPGSGSTPPNQPSGDPPQPNPDSTAAQKVATSPKSALKSPSSKRRTSQNLKLRV
TFEEPVVQMEQPS-LELNG--EKDKDKGRTLQRTSTS--NESGDQLKRPFGAFRSIMETL
SGNQNNNNNYQAANQLKT-STLPLTSLGRKT-TDAKGNPASSTNKGKNKAEM-YSSCINL
SSNTLIEEHLHNYARHNDINRKMKKSYSIKHIAEPESKELFL

MEAPEYLDLD---EIDFSDDIS--------------------------------------
----------YSVTSLKTIPALC-------------------------------------
----------RRCDSQNEDRS-VSSSGWNCGVSTLITNPQKPTGIADVYSKFRPVKRVSP
LKHQPETLENNENEDQKNNT-VEYQKGGETDQGPQPEELSPEDGVGGL-PGKGSEP-SQA
LGELEHYDLDMDEILDVPYIKSSQQLAPLTKVTSEKRILGLCTTINGLS-AKTCPIASTE
NSTPNMTPFCVLSPVKSPHLRKAP-TALRDQHKLSTEDSESSPALGKCGP-AYESENHSK
DFLNKVFSDPHSRKIEKSG-PDCKLRSFHLQSSAAGAKTEE--PINGMNWTN-TQGTEER
TEYLKKVRSILNIVNEGQI

PF12796 // ENSGT00390000001485_0_Domain_0 (440, 516)

SLLPHLAADNLDKIHDENGNNLLHIAASKGHAECLQHLTSL
MGEDCLNERNTEQLTPAGLAIKNGQL--ECVRWMV

ENSGT00390000001485_0_Linker_0_3 (516, 533)

S-ETEAIAELSCSKDFP

PF12796 // ENSGT00390000001485_0_Domain_3 (533, 602)

SLIHYAGC
YGQEK---ILLWLLQFMQEQGISLDEVDREGNSAVHVA-SQHGYLGCIQTLVEYGANVTM
Q

ENSGT00390000001485_0_Linker_3_5 (602, 627)

NHAGEKPSQSAERHGHTLCSRYLVV

PF16700 // ENSGT00390000001485_0_Domain_5 (627, 671)

VETCMSLASQVVKLTKQLKEQTVERVTLQSQLQQ
LLEAQKSEGKSLPSSPSSPSSPASTKSQWKALDTDEESTGKSKVGAQEGIQVLGSLSV--
SSRARTKGKD-EDSDKILR----QL------LGKEISENVC----------TQE--KLSL
EFQDAQA-SSRNSKKIPLEKRELKLARLRQLMQRSLSESDTDSNNSEDPKNTPVKRADRP
RPQPIVESVENVDSAESLHLMIKKHS-LASGRRFP-FGMKASKS-LDGHSPSP-TSESSE
PDLDSHGPGLGMTPPTQPSTEATQSSPDSTAAQKVATSPKSALKSPSSKRRTSQNSKLRV
TFEEPVVQMEQTG-LELNG--EKDKDKGRAPQRT-----SESGEQMKRPFGTFRSIMESL
SGNQNNNNNYQPASQLKT-CTLPLTSLGRKT-ADAKGNPVSPASKGKNKAAM-YSSCIHL
PSNALVEEHLRDYARHNDIKRNATKTYHMKHTAEPEPRELFL

MEAPEYLDLD---EIDFSDDIS--------------------------------------
----------YSVTSLKTIPELC-------------------------------------
----------RRCDSQNEDRS-VSGSSWNCGVSTLITNPQKPTGIADVYSKFRPVKRVSP
LKHQPETLENNENDDQKNNT-VEYQKAGETDQGPPPEELSPEDGVRGL-PGKGSEP-SQA
LGELEHYDLDMDEILDVPYIKSSQQLAPFTKVTSEKRILGLCTTINGLS-GKGCPIGSTE
NATSTMTPFCVLSPVKSPHLRKAK-TVLRDQHKLSTEESENSPALGKCVP-AYESESSSQ
DFLNKAFSDPHGRKTEKTG-PDCKLRAFHLQASAAGPKPEE--QVNGMTWTN-GQGSEER
SEHLKKVRSILNIVKEGQ

PF12796 // ENSGT00390000001485_0_Domain_0 (439, 516)

ISLLPHLAADNLDKIHDENGNNLLHVAASKGHAECLQHLTSL
MGEDCLSERNTEQLTPAGLAIKNGQL--ECVRWMV

ENSGT00390000001485_0_Linker_0_3 (516, 529)

S-ETEAIAELSCS

PF12796 // ENSGT00390000001485_0_Domain_3 (529, 602)

KDFPSLIHYAGC
YGQEK---ILLWLLQFMQEQGISLDEVDQEGNSAVHVA-SQHGYLGCIQTLVEYGANVTM
Q

ENSGT00390000001485_0_Linker_3_5 (602, 627)

NHAGEKPSQSAERHGHTLCSRYLVV

PF16700 // ENSGT00390000001485_0_Domain_5 (627, 671)

VETCMSLASQVVKLTKQLKEQTVERVTLQSQLQQ
LLEAQKSEGKSLPSSPSSPSSPASRKSQWKILDADDEATGKSKTGAQEGIQVLGSLSA--
SSRARTKGKD-EDSDKILR----QL------LGKEISENVC----------TQE--KLSL
EFQDAQV-SSRNSKKIPLEKRELKLARLRQLMQRSLSESDTDSNNSEDPKNTPVRKSDRP
RPQPIVESVENMDSAESLHLMIKKHS-LASGRRFP-FSTKASKY-LDGHSPSP-TSESSE
PDLDSHCPGLGMTPPTQPSADPTQSSPDSSTAQKVATSPKSALKSPSSKRRTSQNSKLRV
TFEEPVVQMEQTS-LELNG--EKDKDRGRAPQRT-----SESGEQMKRPFGTFRSIMETL
SGNQNNNNNYQPANQLKT-CTLPLTSLGRKT-ADTKGNPVSPASKGKNKAEM-YSSCLHL
PSNVRVEEHLRDYARHNDINRNMKKTYNKKHIAEPESKELFL

MEAPEYLDLD---EIDFSDDISD-NRSQGNRLQKLGLEDTDREDALGFGFHRAKLTVVAA
LGACHCPENEYSVTSLKTIPELC-------------------------------------
----------RRCDTQNEDRS-VSSSSWNCGISTLITNTQKPTGIADVYSKFRPVKRVSP
LKHQPETLENNESDDQKNQKVVEYQKGGESDLGPQPEELSPGDGVGGP-PGKSSEP-STS
LGELEHYDLDMDEILDVPYIKSSQQLASFTKVTSEKRILGLCTTINGLS-GKACSTGSSE
SSSSNMAPFCVLSPVKSPHLRKAS-AVIRDQHKLATEETEISPPLVKCGS-AYEPENQSK
DFLNKTFSDPHGRKVEKTT-PDCQLRAFHLQSSAAESKPEE--QVSGLNWTS-TQGPEER
SEYLKKVKSILNIVKEGQI

PF12796 // ENSGT00390000001485_0_Domain_0 (440, 516)

SLLPHLAADNLDKVHDENGNNLLHIAASQGHAECLQHLTSL
MGEDCLNERNTEKLTPAGLAIKNGQL--ECVRWMV

ENSGT00390000001485_0_Linker_0_3 (516, 533)

S-ETEAIAELSCSKDFP

PF12796 // ENSGT00390000001485_0_Domain_3 (533, 602)

SLIHYAGC
YGQEK---ILLWLLQFMQEQGISLDEVDQDGNSAVHVA-SQHGYLGCIQTLVEYGANVTM
Q

ENSGT00390000001485_0_Linker_3_5 (602, 627)

NHAGEKPSQSAERQGHTLCSRYLVV

PF16700 // ENSGT00390000001485_0_Domain_5 (627, 671)

VETCMSLASQVVKLTKQLKEQTVERVTLQNQLQQ
FLEAQKSEGKSLPSSPSSPSSPACRKSQWKSPDADDDSVAKSKPGVQEGIQVLGSLSA--
SSRARPKAKD-EDSDKILR----QL------LGKEISENVC----------TQE--KLSL
EFQDAQA-SSRNSKKIPLEKRELKLARLRQLMQRSLSESDTDSNNSEDPKNTPVRKADRP
RPQPIVESVESMDSAESLHLMIKKHTLASGGRRFP-FSIKTSKS-LDGHSPSP-TSESSE
PDLESQYPGSGSTPPNQPSGDPPQPNPDSTAAQKVATSPKSALKSPSSKRRTSQNLKLRV
TFEEPVVQMEQPS-LELNG--EKDKDKGRTLQRTSTS--NESGDQLKRPFGAFRSIMETL
SGNQNNNNNYQAANQLKT-STLPLTSLGRKT-TDAKGNPASSTNKGKNKAEM-YSSCINL
SSNTLIEEHLRNYARHNDINRKMKKSYSIKHIAEPESKELFL

MEAPEYLDLD---EIDFSDDISD-NGTRGNTLPELGFGVRREEGGLGAESDLV-EVKAST
AGTGRCP-EEYSVTSLKTIPELC-------------------------------------
----------RRCDSQNEDRS-XXXXXXXXXXXXXXXXXXXXTGIADVYSKFRPVKRVSQ
LKQQPETLESNDNDDQKSQK-LEFQKGGEPAPGPPPEELGPGDGGGG--PGKGSEP-GPA
LGELEHYDLDMDEILDVPYIKASPQLAPFSKATSEKRILGLCTTVNGLS-GKACSTGSAE
LAPPSATPFCVLSPMKSPHLRKAP-SGARELHKPPAEGPDSSQPPLPCGS-AYEPENPSK
DFLSKTFGDPRARKAE-QG-PDCQLRAFHLQPAAE-PRPEQPVPVGGPGR-ASSQSPEDR
SEHLKKVRSVLNIVKEGQISLLPRLGADNLDKIHDE

PF00023 // ENSGT00390000001485_0_Domain_0 (457, 490)

NGNNLLHIAASQGHAECLQHLTSL
MGEDCLNERNTEKLTPAGLAIKNGRL--ECVRWMVS-ETEAIAELSCSK

PF00023 // ENSGT00390000001485_0_Domain_3 (530, 569)

DFPSLIHYAGC
YGQEK---ILLWLLQFMQEQGISLDEVD

ENSGT00390000001485_0_Linker_3_4 (569, 570)

Q

PF00023 // ENSGT00390000001485_0_Domain_4 (570, 603)

DGNSAVHVA-SQHGFLGCIQTLVEYGANVTM
QNQAGEKPSQSAERHGHTLCSRYLVVVETCMSLASQVVKLTKQLKXXXXXXXXXXXXLEH
FLEALKSEGKSLPSSPSSPSSPASRKSQWKSPDADDESGAKSKPGVQEGIQVLGSLSA--
PSRARAKTKD-EDSDKILR----QL------LGKEISENVC----------TQE--KLSL
EFQDAQA-SSRNSKKSPLERRELKLARLRQLMQRSLSESDTDSNNSEDPKNTPVRKAERP
RPQPIVESVEGMDSAESLHLMIKKHT-LASGRRFP-FSIKASKS-L-GHSPSP-TSESSE
PDLESQYSGLGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKRRTSQNSKLRF
TFE-PVVHVEQSS-LELSG--EKDKDRGRAPQRRSTS--SESGDQLKRPFGPFRSIMETL
SGNQNNNNNAQA-SPLRT-STLPLPSLGRKT-ADAKGNPVSSASKGKSKAVT-FGSCINL
SSNSLTEEHLRSSARHNDINKKMKKSYSVKHMAEPESKELFL

MEAPEYLDLD---EIDFSDDIS--------------------------------------
----------YSVTSLKTIPALC-------------------------------------
----------RRCDSQNEDRP-VSSSSWNCGVSTLITNPQKPTGIADVYSKFRPVKRVSP
LKHQPETLESNESDDQKNNT-VEYQKGGETDQGPQPEELSPEDGVGGL-PGKGSEP-SQA
LGELEHYDLDMDEILDVPYIKSSQQLAPLTKVTSEKRILGLCTTVNGLS-AKTCPIVSAE
TSTPNMAPLCVLSPVKSPHLRKVP-SVLRDQHKLPAEESENSPAPGKCGP-AFESENHSK
DFLNKVFSDPHSRKAEKSG-PDCKLRPFRLQTSAAGAKPEE--QVNGVSWAS-AQGAEER
TEYLQKVRSILNIVNEGQI

PF12796 // ENSGT00390000001485_0_Domain_0 (440, 516)

SLLPHLAADNLDKIHDENGNNLLHVAASKGHAECLQHLTSL
MGEDCLNERNAEQLTPAGLAIKNGQL--ECVRWMV

ENSGT00390000001485_0_Linker_0_3 (516, 529)

S-ETEAIAELSCS

PF12796 // ENSGT00390000001485_0_Domain_3 (529, 602)

KDFPSLIHYAGC
YGQEK---ILLWLLQFMQEQGISLDEVDQEGNSAVHVA-SQHGYLGCIQTLVEYGANVTM
Q

ENSGT00390000001485_0_Linker_3_5 (602, 627)

NHAGEKPSQSAERHGHTLCSRYLVV

PF16700 // ENSGT00390000001485_0_Domain_5 (627, 672)

VETCMSLASQVVKLTKQLKEQTVERVTLQSQLQQ
LLEAQKSEGKSLPSSPSSPSSPASRKSQWKILDADDESTGKSKLGTQEGIQVLGNL----
SSRARTKGKD-EDSDKILR----QL------LGKEISENVC----------TQE--KLSL
EFQDAQV-SSRNSKKIPLEKRELKLARLRQLMQRSLSESDTDSNNSEDPKNTPVKRVDRP
RPQPIVESVENMDSAESLHLMIKKHS-VASGRRFP-FGMKASKS-LDGHSPSP-TSESSE
PDLDSHCPSLGMTPPTQPSTEATQCSPDSATAQKVATSPKSALKSPSSKRRTSQNSKLRV
TFEEPVVQMEQTS-LELNG--EKDKERGRAPQRT-----SESGEQMKRPFGTFRSIMESL
SGNQNNNNNYQPASQLKT-CTLPLTSLGRKT-ADAKGNPVSPASKGKNKAAM-YSSCIHL
PSNALVEEHLRDYARLNDIKRNTKKTYNVKHIAEPEPKELFL

MEAPEYLDLD---EIDFSDDISD-NRSQGNRLQKLGLEDTDREDAMGFGSHRAKLTVVAA
LGACHCPENEYSVTSLKTIPELC-------------------------------------
----------RRCDTQNEDRS-VSSSSWNCGISTLITNTQKPTGIADVYSKFRPVKRVSP
LKHQPETLENNESDDQKNQKVVEYQKGGESDLGPQPQELGPGDGVGGP-PGKSSEP-STS
LGELEHYDLDMDEILDVPYIKSSQQLASFTKVTSEKRILGLCTTINGLS-GKACSTGSSE
SSSSNMAPFCVLSPVKSPHLRKAS-AVIHDQHKLSTEETEISPPLVKCGS-AYEPENQSK
DFLNKTFSDPHGRKVEKTT-PDCQLRAFHLQSSAAESKPEE--QVSGLNRTS-SQGPEER
SEYLKKVKSILNIVKEGQI

PF12796 // ENSGT00390000001485_0_Domain_0 (440, 516)

SLLPHLAADNLDKIHDENGNNLLHIAASQGHAECLQHLTSL
MGEDCLNERNTEKLTPAGLAIKNGQL--ECVRWMV

ENSGT00390000001485_0_Linker_0_3 (516, 532)

S-ETEAIAELSCSKDF

PF12796 // ENSGT00390000001485_0_Domain_3 (532, 602)

PSLIHYAGC
YGQEK---ILLWLLQFMQEQGISLDEVDQDGNSAVHVA-SQHGYLGCIQTLVEYGANVTM
Q

ENSGT00390000001485_0_Linker_3_5 (602, 627)

NHAGEKPSQSAERQGHTLCSRYLVV

PF16700 // ENSGT00390000001485_0_Domain_5 (627, 671)

VETCMSLASQVVKLTKQLKEQTVERVTLQNQLQQ
FLEAQKSEGKSLPSSPSSPSSPASRKSQWKSPDADDDSVAKSKPGVQEGIQVLGSLSA--
SSRARPKAKD-EDSDKILR----QL------LGKEISENVC----------TQE--KLSL
EFQDAQA-SSRNSKKIPLEKRELKLARLRQLMQRSLSESDTDSNNSEDPKTTPVRKADRP
RPQPIVESVESMDSAESLHLMIKKHTLASGGRRFP-FSIKASKS-LDGHSPSP-TSESSE
PDLESQYPGSGSIPPNQPSGDPQQPSPDSTAAQKVATSPKSALKSPSSKRRTSQNLKLRV
TFEEPVVQMEQPS-LELNG--EKDKDKGRTLQRTSTS--NESGDQLKRPFGAFRSIMETL
SGNQNNNNNYQAANQLKT-STLPLTSLGRK--TDAKGNPASSASKGKNKAEM-YSSCINL
SSNMLIEEHLCNDTRHNDINRKMKKSYSIKHIAEPESKELFL

MEAPEYLDLD---EIDFSDDIS--------------------------------------
----------YSVTSLKTIPELC-------------------------------------
----------RRCDTQNEDRS-VSSSSWNCGISTLITNTQKPTGIADVYSKFRPVKRVSP
LKHQPETLENNESDDQKNQKVVEYQKGGESDLGPQTEELSPGDGVGGP-PGKSSEP-STL
LGELEHYDLDMDEILDVPYIKSSQQLASFTKVTSEKRILGLCTTINGLS-GKACSTGSSE
SSSSNMAPFCVLSPVKSPHLRKAS-AVIRDQHKLATEETEISPPLVKCGS-AYEPENQSK
DFLNKTFSDPHGRKVEKTT-PDCQLRAFHLQSSAAESKPEE--QVSGLNWTS-SQGPEER
SEYLKKVKSILNIVKEGQISLLPHLAADNLDKIHDENGNNLLHIAASQGHAECLQHLTSL
MGEDCLNERNTEKLTPAGLAIKNGQL--ECVRWMVS-ETEAIAELSCSKDFPSLIHYAGC
YGQEK---ILLWLLQFMQEQGISLDEVDQ

PF00023 // ENSGT00390000001485_0_Domain_4 (570, 602)

DGNSAVHVA-SQHGYLGCIQTLVEYGANVTM
QNHAGEKPSQSAERQGHTLCSRYLVVVETCMSLASQVVKLTKQLKEQTVERVTLQNQLQQ
FLEAQKSEGKSLPSSPSSPSSPACRKSQWKSPDADDDSVAKSKPGVQEGIQVLGSLSA--
SSRARPKAKD-EDSDKILR----QL------LGKEISENVC----------TQE--KLSL
EFQDAQS-SSRNSKKIPLEKRELKLARLRQLMQRSLSESDTDSNNSEDPKNTPVRKADRP
RPQPIVESVESMDSTESLHLMIKKHTLASGGRRFP-FSIKTSKS-LDGHSPSP-TSESSE
PDLESQYPGSGSTPPNQPSGDPPQPNPDSTAAQKVATSPKSALKSPSSKRRTSQNLKLRV
TFEEPVVQMEQPS-LELNG--EKDKDKGRTLQRTSTS--NESGDQLKRPFGAFRSIMETL
SGNQNNNNNYQAANQLKT-STLPLTSLGRKT-TDTKGNPASSTNKGKNKAEM-YSSCISL
SSNTLIEEHLHNYARHNDINRKMKKSYSIKHIAEPESKELFL

MEAPEYLDLD---EIDFSDDISD-DRSPGNRLQKLGLEDTDREDALGFVSHRAKLTVVAA
LGACHCPENEYSVTSLKTIPELC-------------------------------------
----------RRCDTQNEDRS-VSSSSWNCGISTLITNTQKPTGIADVYSKFRPVKRVSP
LKHQPETLENNESDDQKNQKVVEYQKGGESDLGPQPQELGPGNGVGGP-PGKSSEP-STS
LGELEHYDLDMDEILDVPYIKSSQQLASFTKVTSEKRILGLCTTINGLS-GKACSTGSSE
SSSSNMAPFCILSPVKSPHLRKAS-AVIHDQHKLSTEETEISPPLVKCGS-AYEPENQSK
DFLNKTFSDPHGRKVEKTI-PDCQLRAFHLQSSAAESKPEE--QVSGLNWTS-SQGPEER
SEYLKKVKSILNIVKEGQI

PF12796 // ENSGT00390000001485_0_Domain_0 (440, 516)

SLLPHLAADNLDKIHDENGNNLLHIAASQGHAECLQHLTSL
MGEDCLNERNTEKLTPAGLAIKNGQL--ECVRWMV

ENSGT00390000001485_0_Linker_0_3 (516, 532)

S-ETEAIAELSCSKDF

PF12796 // ENSGT00390000001485_0_Domain_3 (532, 602)

PSLIHYAGC
YGQEK---ILLWLLQFMQEQGISLDEVDQDGNSAVHIA-SQHGYLGCIQTLVEYGANVTM
Q

ENSGT00390000001485_0_Linker_3_5 (602, 627)

NHAGEKPSQSAERQGHTLCSRYLVV

PF16700 // ENSGT00390000001485_0_Domain_5 (627, 671)

VETCMSLASQVVKLTKKLKEQTVERVTLQNQLQQ
FLEAQKSEGKSLPSSPSSPSSPASRKPQWKSPDADDDSVAKSKPGVQEGIQVLGSLSA--
SSRARPKAKD-EDSDKILR----QL------LGKEISENVC----------TQE--KLSL
E-QDAQA-SSRNSKKIPLEKRELKLARLRQLMQRSLSESDTDSNNSEDPKNTPVRKADRP
RPQPIVESVESMDSAESLHLMIKKHTLASGGRRFP-FSIKASKS-LDGHSPSP-TSESSE
PDLESQYPGSGSIPPNQPSGDPPQPSPDSTAAQKVATSPKSALKSPSSKRRTSQNLKLRV
TFEEPVVQMEQPS-LELNG--EKDKDKGRTLQRTSTS--NESGDQLKRPFGAFRSIMETL
SGNQNNNNNYQAANQLKT-STLPLTSLGRKT-TDAKGNPASSASKGKNKAEM-YSSCINL
SSNMLIEEHLRNDARHNDINRKMKKSYSIKHIAEPESKELFL

MEAPEYLDLD---EIDFSDDISD-NRSQGNKLQKLGLEDTDREDALGFGSHRAKLTVVAA
LGACHCPENEYSVTSLKTIPELC-------------------------------------
----------RRCDTQNEDRS-VSSSSWNCGISTLITNTQKPTGIADVYSKFRPVKRVSP
LKHQPETLENNESDDQKNQKVVEYQKGGESDLGPQPEELSPGDGVGGP-PGKSSEP-STS
LGELEHYDLDMDEILDVPYIKSSQQLASFTKVTSEKRILGLCTTINGLS-GKACSTGSSE
SSSSNMAPFCVLSPVKSPRLRKAS-AVIRDQHKLATEETEISPPLVKCGS-AYEPENQSK
DFLNKTFSDPYGRKVEKTT-PDCQLRAFHLQSSAAESKPEE--QVSGLNWTS-SQGPEER
SEYLKKVKSILNIVKEGQI

PF12796 // ENSGT00390000001485_0_Domain_0 (440, 516)

SLLPHLAADNLDKIHDENGNNLLHIAASQGHAECLQHLTSL
MGEDCLNERNTEKLTPAGLAIKNGQL--ECVRWMV

ENSGT00390000001485_0_Linker_0_3 (516, 532)

S-ETEAIAELSCSKDF

PF12796 // ENSGT00390000001485_0_Domain_3 (532, 602)

PSLIHYAGC
YGQEK---ILLWLLQFMQEQGISLDEVDQDGNSAVHVA-SQHGYLGCIQTLVEYGANVTM
Q

ENSGT00390000001485_0_Linker_3_5 (602, 627)

NHAGEKPSQSAERQGHTLCSRYLVV

PF16700 // ENSGT00390000001485_0_Domain_5 (627, 671)

VETCMSLASQVVKLTKQLKEQTVERVTLQNQLQQ
FLEAQKSEGKSLPSLPSSPSSPASRKSHWKSPDADDDSVAKSKPGVQEGIQVLGSLSA--
SSRARPKAKD-EDSDKILR----QL------LGKEISENVC----------TQE--KLSL
EFQDAQA-SSRNSKKIPLEKRELKLARLRQLMQRSLSESDTESNNSEDPKNTPVRKADRP
RPQPIVESVESMDSAESLQLMIKKHTLASGGRRFP-FSIKTSKS-LDGHSPSP-TSESSE
PDLESQYPGSGSSPPNQPSGDPPQPNPDSTAAQKVATSPKSALKSPSSKRRTSQNLKLRV
TFEEPVVQMEQPS-LELNG--EKDKDKGRTLQRTSTS--NESGDQLKRPFGAFRSIMETL
SGNQNNNNNYQAANQLKT-STLPLTSLGRKT-PDAKGNPASSTNKGKNKAEM-YSSCINL
SSNTLIEEHLRNYARHNDINRKMKKSYSIKHIAEPESKELFL

MEAPEYLDLD---EIDFSDEIS--------------------------------------
----------YSVTSLKTIPELC-------------------------------------
----------RRCDSQNEDRS-VSSTNWSCGVSTLIGNAQKPTGIADVYSKFRPVKRVSP
LKHQPESSENNESDDQKNQK-VEYQKGNDSHSASQNDDQCPGNGDGL--KSKSIES-GVL
LGELEHYDLDMDEILDVPYIKSSQQLAAFTKVTPEKRILGVYSTVNGLS-GKTCSVGNSE
NLPASTTQFCVLSPVNSSQMRNAQ-SIVLNQNKHLAEELELSQPLVKCSS-VQETEAQNK
GFLNRTFTNPQAHKTEKTM-PNCHLRTFHLQTTAATENKLEE-QNSNMNWSS-SGAPEEK
GEDMKKNKSILNIVKEGQISLLPHLAADNLDKIHDESENNLLHIAASQGHAECLQHLTSL
MGEDCLNERNNEQLTPAGLAIKNG--QLECVRWMVS-ETEAIAELSCSKDHPSLIHYAGC
YGQEK---ILLWLLQFMQEQGISLDEVDQ

PF00023 // ENSGT00390000001485_0_Domain_4 (570, 602)

DGNSAVHVA-AQHGYLGCIQTLVEYGANVTM
QNRAGEKPSQTAERHGHTMCSRYLVVVETCMSLASQVVKLTKQLKEQTVERVTLQNQLQQ
LLEAQRSEGKSLPTSPSSPLSPASGKSQWKPSGADDLSLPKRKLNTQDGIQILGGMGTSS
--CTQSKTKD-EDSDKILR----QL------LGKELSENVC----------MQE--KLTL
EFHD----SSKNVKKILPEKRELKLARLRHLMQRSLSESDTDSNNSEDLKNTPVKRTDKP
RPQPIVEGVE---NTENLHLMIKKHT-SAAGRRFP-FGIRASKS-LDGHSASP-SSESSD
PDNESQYQ-SGIASQSQVSADTSQSSTDSVAVQKVATSPKSALKSPSSKRRTSQNLKLRV
TFEEPIVQMEQTE-TELNE--EKDKDRGKGPPRAPAN--AEPGDQLKRPFGTLRSIMETL
SGNQNNNNNCQTANLIKTSSTLPFTSLGRKA-ADSKGNPVA-PTKGKHKTGP-YSSYTNL
SSSMLIEEHLYNYAWHNDINRKSLKSYSQKNIEEPELQEFFL

MEAPEYLDLD---EIDFSDDVSH-STQDRRQ-----------------------KTKLWV
------YRDNYSVTSLKTIPELC-------------------------------------
----------RRCDSQNEDRS-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXX-XXXXXXXXXXXXX-XXXXXXX-XXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXX-XXXXXXXXXX-XXXXXXXXX
XXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXPHLAADNLDKIHDE

PF00023 // ENSGT00390000001485_0_Domain_0 (457, 477)

SGNNLLHIAASQGHAECLQHLTSL
MGEDCLSERNAEKLTPAGLAIKNGQL--ECVRWMVS-ETEAIAELSCSKDFPSLI

PF00023 // ENSGT00390000001485_0_Domain_3 (536, 569)

HYAGC
YGQEK---ILLWLLQFMQEQGISLDEVD

ENSGT00390000001485_0_Linker_3_4 (569, 570)

Q

PF00023 // ENSGT00390000001485_0_Domain_4 (570, 589)

DGNSAVHIA-SQRGYLGCIQXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTKQLKXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXSPSSPTSRNSQWRPPEADDESRARNKPGVQEGIRVLGSLSA--
SSRARTKAKD-EDSDKILR----QL------LGKEISENVC----------TRE--KLSL
EFQDAQA-SSRNSKKIPPEKRELKLVRLRQLMQRSLSESDTDSNHSEDPKTTPVKKADRP
RPQPIVENVESMDSAESLHLMIKKHT-LASGRRFP-FSIKASKS-LDGHSPSP-TSESSE
PDLESQYPGSSNTPPNQPAGDSTQPSPESAAAQKVATSPKSALKSPSSKRRTSQNLKLRV
TFEEPVVQMEQTS-LELNG--EKDRDRGRTPQRTSSS--SESGDQLKRPFGTFRSIMETL
SGNQNNNNNYQAANQLKI-STPPLTSLGKKT-TDTKGNPVSLASKGKNKTXX-XXXXXXX
XXXXXXXXXXXXXXXHSDINREMKKSHNVKHIAEPESKELFL

---------M---KLTLVMTYLD-NRSQGNRLQKLGLEDTDREDAMGFSSHRAKLTVVAA
LGACHCPENEYSVTSLKTIPELC-------------------------------------
----------RRCDTQNEDRS-VSSSSWNCGISTLITNTQKPTGIADVYSKFRPVKRVSP
LKHQPETLENNESDDQKNQKVVEYQKGGESDLGPQPQELGPGDGVGGP-PGKSSEP-STS
LGELEHYDLDMDEILDVPYIKSSQQLASFTKVTSEKRILGLCTTINGLS-GKACSTGSSE
SSSSNMAPFCVLSPVKSPHLRKAS-AVIHDQHKLSTEETEISPPLVKCGS-AYEPENQSK
DFLNKTFSDPHGRKVEKTT-PDCQLRAFHLQSSAAESKPEE--QVSGLNRTS-SQGPEER
SEYLKKVKSILNIVKEGQI

PF12796 // ENSGT00390000001485_0_Domain_0 (440, 516)

SLLPHLAADNLDKIHDENGNNLLHIAASQGHAECLQHLTSL
MGEDCLNERNTEKLTPAGLAIKNGQL--ECVRWMV

ENSGT00390000001485_0_Linker_0_3 (516, 532)

S-ETEAIAELSCSKDF

PF12796 // ENSGT00390000001485_0_Domain_3 (532, 602)

PSLIHYAGC
YGQEK---ILLWLLQFMQEQGISLDEVDQDGNSAVHVA-SQHGYLGCIQTLVEYGANVTM
Q

ENSGT00390000001485_0_Linker_3_5 (602, 627)

NHAGEKPSQSAERQGHTLCSRYLVV

PF16700 // ENSGT00390000001485_0_Domain_5 (627, 671)

VETCMSLASQVVKLTKQLKEQTVERVTLQNQLQQ
FLEAQKSEGKSLPSSPSSPSSPASRKSQWKSPDAEDDSVAKSKPGVQEGIQVLGSLSA--
SSRARPKAKD-EDSDKILR----QL------LGKEISENVC----------TQE--KLSL
EFQDAQA-SSRNSKKIPLEKRELKLARLRQLMQRSLSESDTDSNNSEDPKTTPVRKADRP
RPQPIVESVESMDSAESLHLMIKKHTLASGGRRFP-FSIKASKS-LDGHSPSP-TSESSE
PDLESQYPGSGSIPLNQPSGDPQQPSPDSTAAQKVATSPKSALKSPSSKRRTSQNLKLRV
TFEEPVVQMEQPS-LELNG--EKDKDKGRTLQRTSTS--NESGDQLKRPFGAFRSIMETL
SGNQNNNNNYQAANQLKT-STLPLTSLGRK--TDAKGNPASSASKGKNKAEM-YSSCINL
SSNMLIEEHLRNDTRHNDINRKMKKSYSIKHIAEPESKELFL

MEAPEYLDLD---EIDFSDDIS--------------------------------------
----------YSVTSLKTIPELC-------------------------------------
----------RRCDSQNEDRS-VSSSSWNCGVSTLITNPQKPTGIADVYSKFRPVKRVSP
LKHQPETLENNENDDQKNHT-VEYEKVGETDPSPQPEELSPEDGVEGL-PGKGSEP-SPA
LGELEHYDLDMDEILDVPYIKSSQQLASFTKVTSEKRIVGLCTTINGLS-GKACPTGSTE
NSTSNMTPFCVLSPVKSPHLRKAS-ALLRDQHKLSTEPSESSPPLSKCGS-AYEPENQSK
DFLNKAFSDPHSRKTEKTV-TDCQLRAFHLQSSATDPKLDE--QVSGMNWISSGQGPEGR
SEDVKKVRSILNIIKEGQIS

PF12796 // ENSGT00390000001485_0_Domain_0 (441, 516)

LLPHLAADNLDKIHDENGNNLLHIAASQGHTECLQHLTSL
MGEDCLSERNTEKLTPAGLAIKNGQL--ECVRWMV

ENSGT00390000001485_0_Linker_0_3 (516, 532)

S-ETEAIAELSCSKDF

PF12796 // ENSGT00390000001485_0_Domain_3 (532, 602)

PSLIHYAGC
YGQEK---ILLWLLQFMQEQGISLDEVDQDGNSAVHVA-SQHGYLGCIQTLVEYGANVTM
Q

ENSGT00390000001485_0_Linker_3_5 (602, 627)

NHAGEKPSQSAEWHGHTLCSRYLVV

PF16700 // ENSGT00390000001485_0_Domain_5 (627, 671)

VETCMSLASQVVKLTKQLKEQTVERVTLQNQLQQ
LLEAQKSEGKSLPSSPSSPSSPASRKSQWKVPDADDEATAKNKPGVHEGIQVLGSLSA--
SSRARTKGKD-EDSDKILR----QL------LGKEISENVC----------TQE--KLSL
EFQDAQA-SSRSSKKIPLEKRELKLARLRQLMQRSLSESDTDSNNSEDPKNTPVKKADRP
RPQPIVETVENMDSAESLHLMIKKHS-LASGRRFP-FGTKASKS-LDGHSPSP-TSESSE
PDLDPQGPGSGITPPNQSSADPTQSSPDSTAAQKVATSPKSALKSPSSKRRTSQNSKLRV
TFEEPVVQMEQTS-LELNG--DKDKDRGRTLQRTPAG--SETGEQMKRPFGTFRSIMETL
SGNQNNNNNYQPTNQLKT-STLPLTSLGRKT-TDAKGNPVSSASKGKNKAEM-YSSCINL
SSNLLTEEHLRNYIRYNDINRKM-KSYSTKHIAEPESKELFL

MEAPEYLDLD---EIDFSDDISGHRN-----MPKPGLEGRRQGEALGL--VLLLTTLMTA
LGAGHCPEHEYSVTSLKTIPELC-------------------------------------
----------RRCDSQNEDRS-VSSSGWNCGISALITNTQKPTGIADVYSKFRPVKRVSP
LKHQPETLESTESDDQKNQK-VDFQKGGDADPGPQPEELGPEEGVGGP-PRKGSEP-PTS
LGELEHYDLDMDEILDVPYIKSSQQLASFTKATSEKRILGLCTTINGLAASKACSAGGAE
NPPSTMTPFCVLSPVKSPHLRKAP-PTVHDQHKLAPEESESVPALVQCGS-TYEPENQSG
DLVNKAFSELPSGRVEKAL-SDCQLRGFRLPCSAAETKLEE--PVNGVSWTS-CQGPEER
TEYQNKARSILNIVREGQISLLPHLAADNLDKIHDE

PF00023 // ENSGT00390000001485_0_Domain_0 (457, 490)

NGNNLLHIAASQGHAECLQHLTSL
MGEDGLNERNAGKLTPAGLAIKNGQL--ECVRWMVS-ETEAIAELSCSK

PF00023 // ENSGT00390000001485_0_Domain_3 (530, 569)

DFPSLIHYAGC
YGQEK---ILLWLLQFMQEQGISLDEVD

ENSGT00390000001485_0_Linker_3_4 (569, 570)

Q

PF00023 // ENSGT00390000001485_0_Domain_4 (570, 603)

DGNSAVHVA-SQHGFLGCIQTLVEYGANVTM
QNHAGEKPSQSAERHGHTLCSRYLVVVETCMSLASQVVKLTKQLKEQTVERVTLQTQLQQ
LLEAQKSEGKSLPSSPSSPSSPASRNAQWKSPDAEEESAAKSKPGLQEGIPALSSLST--
CSRARARAKD-EDPDKILR----QL------LGKEISENVC----------TQE--KLSL
EFQDAQA-SSRNPKKIPVEKRELKLARLRQLMQRSLSESDTDATNAEDPKATPLRKPERP
RPQPVVESVEGVDSTESLHLMIKKHS-VASTRRFP-FGIKASKP-LDGHSPSP-TSEGSE
ADMESQYVSPGSTAPGQGPGDSAQPSPDSLAAQKVATSPKSALKSPSSKRRTSQNLKLRV
TFEEPVVQMEQTS-IDPNG--ERDKDRGRTAPRASPG--GESGDQLKRPFGTFRSIMETL
SGNQNNNNNSQTASQLKT-STLPLTSLGRKT-TDAKGSLVSSAGKGKSKAGM-FGSCASL
SSSMLTEEPLRGCARHNDINRKMKKSYSIKHIAEPESKELFL

MEAPEYLDLD---EIDFSDDISY-SVTSLKT-IP--------------------------
---ELC------------------------------------------------------
----------RRCDSQNEDRS-VSSSGWNCGVSTLITNTQKPTGIADVYSKFRPVKRVSP
LKHQPETLENNESDDQ---K-AEYQKGGDPDPGPQPEELGPRAVEGSP-QRKSAEP-STL
LGELEHYDLDMDEILDVPYIKSSQQLASFTKATSEKRILGLCTSINGLS-GKACPTGNAE
SSPSNMTPFCVLSPVKSPHLRKAS-S-VQDQQKLSPEESESSPPPVKCGS-AYEPENQGK
DVLHKTFSDPHSRKVDKAMAPDCQLRAFHLQSSATDPKLEE--QIGGMNWTS-SQGPEER
SEHLKKVKSVLNIVREGQISLLPHLAADNLDKIHDESGNNLLHVAASQGHAECLQHLTSL
MGEDCLNERNVEKLTPAGLAIKNGQL--ECVRWMVS-ETEAIAELSCSKDFPSLIHYAGC
FGQEK---ILLWLLQFMQEQGISLDEVDQ

PF00023 // ENSGT00390000001485_0_Domain_4 (570, 602)

DGNSAVHVA-SQHGYLGCIQTLVEYGANVTM
QNHAGEKPSQSAERHGHSLCSRYLVVVETCMSLASQVVKLTKQLKEQTMQRVTLQNQLQQ
LLEAQKSEGKSLLSSPSSPSSPACRKSQWKSPDAEDESVAKSKPGVQEGIQVLGSLSA--
SSRARAKVKD-EDSDKILR----QL------LGKDISENVC----------TQE--KLSL
EFQDAQT-SSRHSKKIPLEKRELKLARLKQLMQRPLSEADTDSNNSEDPKGTPVRKVDRP
RPQPIVESVEGMDSAESLHLMIKKHT-LASGRRFP-FSIKASKS-LEGHSPSP-TSESSE
PDLESQCPGSGNTPSSQPSGEAPQPSPDSAAAQKVATSPKSALKSPSSKRRTSQNSKLRV
TFEEPVVQMEQTS-LELNG--EKEREKGRTLQRTSAG--SESGDQLKRPFGTFRSIMETL
SGNQNNNNNYQASSQLKT-STLPLTSLGRKV-TDGKGNTGSSASKGKNKAEM-YGSCINL
SSNTLIEEHLHNYARHDDISRKMKKSYSIKHVAEPESKELFL

MEAPEYLDLD---EIDFSDDIS--------------------------------------
----------YSVTSLKTIPELC-------------------------------------
----------RRCDSQNEDRA-VSNSSWNCGVSTLIANTQKPTGIADVYSKFRPVKRVSP
LKHQPETLENNESDDQKNQK-VEHEKGSDSDSGPPPEELSQGDGEGGL-QGRLTEP-SAL
LGELEHYDLDMDEILDVPYIKSSQQFASFTKVTSEKRILGLCSTINGLS-GKACSTGSAE
NSPSNTTPFCVLSPVKSPHLRKTS-SVVSDQHKLSTEEPESSSPLGKCGS-TYEPENQSK
DFLNKTFSDPPSRKVEKAV-PDCQLRAFHLPPSATEPKLEE--QISGMIWTS-SQGPEEK
SEYLKKAKSILNIVKEGQISLLPHLAADNLDKIHDESGNNLLHIAASQGHAECLQHLTSL
MGEDCLSERNAGKLTPAGLAIKNGQL--ECVRWMVS-ETEAIAELSCSKDFPSLIHYSGC
YGQEK---ILLWLLQFMQEQGISLDEVDQ

PF00023 // ENSGT00390000001485_0_Domain_4 (570, 602)

DGNSAVHVA-SQHGYLGCIQTLVEYGANVTI
QNHAGEKPSQSAERHGHTLCSRYLVVVETCMSLASQVVKLTKQLKEQTVERVTLQNQLQQ
LLEAQRSEGKSLPSSPSSPSSPTSRKSQWKSPDADDESTAKSKPGIQEGMQVLGNLSA--
SSRAKAKAKD-EDSDKILR----QL------LGKEISENVC----------TQE--KLSL
EFQDAQA-SSRNLKKIPPEKRELKLARLRQLMQRSLSESDTDSNNSEDPKNTPVRKADRP
RPQPIVESVESMDSAESLHLMIKKHT-LSSGRRFP-FIIKASKS-LDGHSPSP-TSESSE
PDLESQYPGSGNTPPNQPSGDPTQPSPDSAGAQKVATSPKSALKSPSSKRRTSQNLKLRV
TFEEPVVQMEQTS-LELNG--EKDRDKGRSLQRSSTS--NESGDQLKRPFGTFRSIMETL
SGNQNNNNNYQSTSQLKT-STLPLTSLGRKT-TDAKGNPVSSASKGKNKAGT-FGSCSHL
SSNMLIEEHLRNYARHNDINRKMKKSYSIKHIAEPESKELFL

MEAPEYLDLD---EIDFSDDIS--------------------------------------
----------YSVTSLKTIPELC-------------------------------------
----------RRCDSQNEDRA-VSSSGWNCGISTLLTNTQKPTGIADVYSKFRPVKRVSP
LKHQPETLENNESDDQKNHK-GEYQKGGESDQGPQAEELSPEDGGGSV-PGKSSEP-SSA
LGELEHYDLDMDEILDVPYIKSSQQLASFTKAPSEKRILGLCTTLNGLP-GKACSPGSSE
NSPSTMTPFCILSPVKSPPSRKAP-AVFRDPHKLLTEAAENSPPSGKCVP-AYAPENQNK
GFLNKAFSDPHDRKMEKTA-PDCHLRAFHSQSSASEPNLEE--QVSGTAWTS-SQGPEER
NEHLKKVKSILNIVKEGQISLLPHLAADNLDKIHDDSGNNLLHVAASQGHAECLQHLTSL
MGEDCLNERNVEKLTPAG

PF12796 // ENSGT00390000001485_0_Domain_3 (499, 602)

LAIKNGQL--ECVRWMVS-ETEAIAELSCSKDFPSLIHYAGC
YGQEK---ILLWLLQFMQEQGISLDEVDYEGNSAVHVA-SQHGYLGCIQTLVEYGANVTM
Q

ENSGT00390000001485_0_Linker_3_5 (602, 627)

NHAGEKPSQSAERHGHTLCSRYLVV

PF16700 // ENSGT00390000001485_0_Domain_5 (627, 671)

VETCMSLASQVVKLTKQLKEQTMERVTLQNQLQQ
LLEAQKSEDKSLPSL---PSSPASRKSHWKVPDASDESVAKSKPGVQEGIQVLGSLSA--
SSRVRAKAKD-EDSDKILR----QL------LGKEISENVC----------TQE--KLTL
EFQDAQA-CSRNPKKIPLEKRELKLARLRQLMQRSLSESDTDSNNSEDPKNTPVRKADRP
RPQPIVESVENMDSTESLHLMIKKHS-LASGRRFP-FSTKASKS-LDGHSPSP-TSENSE
PDLESQCLGLGSIPPSQPSGDPTQSNPDSAAAQKVATSPKSALKSPSSKRRTSQNLKLRV
TFEEPVVQMEPSSVLELDGDKDKDRDKGRTLPRNSTS--SESGEQLKRPFGTFRSIMESL
SGNQNNNNNCPAASQLKT-STLPLTSLGRKT-ADNKGNPVSSASKGKSKAEM-YSSCLSL
ASNTLIEEHLHNCARHNDINRKMKKS-NIKHIAEPESKELFL

------------------------------------------------------------
------------------------------------------------------------
-------------------KT-VSSSGWNCGVSTLITNTQKPTGIADVYSKFRPVKRVSP
LKHQPETLENNESDDQKNQK-AEYQKGNDPDPGPQPEELGPRAVEGSP-QRKSTEP-STL
LGELEHYDLDMDEILDVPYIKSSQQLASFTKATSEKRILGLCTSINGLS-GKACPTGSAE
SSPSNMTPFCVLSPVKSPHLRKAS-SVVQDQQKLSPEESESSPPLVKSGS-AYEPENQGK
DFLHKTFSDPHSRKVDKAMAPDCQLRAFHLQSSATDPKLEE--QIGGMNWTS-SQGPEER
NEYLKKVKSILNIVKEGQISLLPHLAADNLDKIHDESGNNLLHVAASQGHAECLQHLTSL
MGEDCLNERNVEKLTPAGLAIKNGQL--ECVRWMVS-ETEAIAELSCSKDFPSLIHYAGC
FGQEK---ILLWLLQFMQEQGISLDEVDQ

PF00023 // ENSGT00390000001485_0_Domain_4 (570, 602)

DGNSAVHVA-SQHGYLGCIQTLVEYGANVTM
QNHAGEKPSQSAERHGHSLCSRYLVVVETCMSLASQVVKLTKQLKEQTTQRVTLQNQLQQ
LLEAQKSEGKSLLSSPSSPSSPACRKSQWKSPDAEDESVAKSKSGVQEGIQVLGSLSA--
SSRARAKVKD-EDSDKILR----QL------LGKDISENVC----------TQE--KLSL
EFQDAQT-SSRHSKKIPLEKRELKLARLKQLMQRPLSEADTDSNNSEDPKGTPVRKVDRP
RPQPIVESVEGVDSAESLHLMIKKHT-LASGRRFP-FSIKASKS-LEGHSPSP-TSESSE
PDLESQCPGSGNTPSSQPSGEAPQPSPDSTAAQKVATSPKSALKSPSSKRRTSQNSKLRV
TFEEPVVQMEQTS-LELNG--EKEREKGRTLQRTSAA--SESGDQLKRPFGTFRSIMETL
SGNQNNNNNYQASNQLKT-STLPLTSLGRKV-TDGKGNTGSSASKGKNKAEM-YGSCINL
SSNTLIEEHLHNYARHDDISRKMKKSYSIKHVAEPESKELFL

MEAPEYLDLD---EIDFSDDIS--------------------------------------
----------YSVTSLKTIPELC-------------------------------------
----------RRCDSQNEDRS-VSSSSWNCGVSTLITNPQKPTGIADVYSKFRPVKRVSP
LKHQPETLENNENDDQKNST-VEYQKGGETDQGSQPEELNPEDGVRGL-PGKGSEP-SQA
LGELEHYDLDMDEILDVPYIKSSQQLAPLTKVTSEKRILGLCTTINGLS-GKACPIGSTE
NSTVNMTPFCVLSPVKSPHLRKAS-TTLRDQNKLSTEDSENSPVLGKCVP-AYESENHSK
DFLNKAFSDPHSRKIEKTG-PDCKLRAFHLPSSAAGAKAEE--QVNGMNWTN-AQGTEER
NEYLKKVRSIVNIVKEGQISLL--------------------------------------
------------------------------------------------------------
---EK---ILLWLLQFMQEQGISLDEVDQEGNSAVHVA-SQHGYLGCIQTLVEYGANVTM
QNHAGEKPSQSAERHGHTLCSRYLVV

PF16700 // ENSGT00390000001485_0_Domain_5 (627, 671)

VETCMSLASQVVKLTKQLKEQTVEHVTLQNQLQQ
LLEAQKSEGKSLPSSPSSPSSPASRKSQWKILDADDEATGKSKPGAQEGIQVLGSLSA--
SSRARTKGKD-EDSDKILR----QL------LGKEISENVC----------NQE--KLSL
EFQDAQA-SSRNSKKIPLEKRELKLARLRQLMQRSLSESDTDSNNSEDPKNTPVRRADRP
RPQPIVESVENMDSTESLHLMIKKHS-LASGRRFP-FSTKASKS-LDGHSPSP-TSESSE
PDLDSHCPGLGMTSPTQPSADPSQSSPDSSTAQKVATSPKSALKSPSSKRRTSQNSKLRV
TFEEPVVQVEQTS-LELNG--EKDKDRVRAPQRT-----SESGEQMKRPFGTFRSIMETL
SGNQNNNNNYQPANQLKT-CTLPLTSLGRKT-ADTKGNPVSPGSKGKNKAEM-YSSCIYL
PSNVLVEEHLRDYARRNDINRNTKKTYSRKHIAEPESKELFL

MEAPEYLDLD---EIDFSDDIS--------------------------------------
----------YSITSLKTIPELC-------------------------------------
----------RRCDSQNEDRS-VSSSSWNCGGSALIGNAQKPTGIADACNKFRPVKRVSP
LKHQPESCENNESDDQKNQK-GEYQKGSESQPAPPNDDQSPGEGENL--KSKNIEP-TVL
LGELEHYDLDMDEILDVPYIKSNQQLVPFTKVAPEKKTFGVSSTVNGVS-GKTCSTEST-
-EPAGVTQFCVLSPVKGSQLRKTQ-PIVLDQHKHLTEELELSQPLAKCSS-VHETEAQGK
GFLCRTFVGPQAHKTEKTM-PNCHLRTFHLQTTVAESKQLEE---LNMSWSS-AGGPEER
SEEVKKFKSILNIVKEGQISLLPHLAADNLDKIHDECDNNLLHVAASKGHAECLQHLTSL
MGEDCLNERNMEQLTPAGLAIKNG--QLECVRWMVS-ETEAIAELSCSK

PF12796 // ENSGT00390000001485_0_Domain_3 (530, 602)

DHPSLIHYAGC
YGQEK---ILLWLLQFMQEQGISLDEVDQDGNTAVHIA-AQHGYLGCIQTLVEYGANVTM
Q

ENSGT00390000001485_0_Linker_3_5 (602, 627)

NHVGEKPSQSAERHGHTMCSRYLVV

PF16700 // ENSGT00390000001485_0_Domain_5 (627, 671)

VETCMSLASQVVKLTKQLKEQTVERVTLQNQLQQ
LLEAQRPEGKSLPTSTSSPSSPASGKPQWKPTEADELSPPKSKLNAQDGIQILGSLGTS-
-SRTRAKIKD-EDSDKILR----QL------LGKEISENVC----------MQE--KLTL
EFQDAHA-SSKNVKKILPEKRELKLARLRQLMQRSLSESDTDSANSEDHKNTPVKRTDKL
RPQPIVESVE---SAESLHLMIKKHA-SAAGRRFP-FGTRASKS-VDGHSPSP-TSESSD
PDNEAQYQ-SGTVPQSQFCGDSSPSSTDGAAAQKVATSPKSALKSPSSKRRTSQNLKLRV
TFEEPVVQVELAE-AELNE--EK--DKGKALPRAPASTGEPSGDQLKRPFGTFRSIMETL
SGNQNNNNNCQTANLIKTSSTLPFSSLGRKA-GDSKGNPAA-LTKGRNKPGP-CFSYTNL
SSSTLNEEHLCNYAWHDNISRKSQKSYSQKSSEETELQEFFL

MEAPEYLDLD---EIDFSDDIS--------------------------------------
----------YSVTSLKTIPALC-------------------------------------
----------RRCDSQNEDRS-VSSSGWNCGVSTLITNPQKPTGIADVYSKFRPVKRVSP
LKHQPETLENNENEDQKNNT-VEYQKGGETDQGPQPEELSPEDGVGGL-PGKGSEP-SQA
LGELEHYDLDMDEILDVPYIKSSQQLAPLTKVTSEKRILGLCTVINGLS-AKTCPITSTE
NSTPNMTPFCVLSPVKSPHLRKAP-TALRDQHKLSTEDCESSPALGKCGP-ANESENHSK
DFLNKVFSDPHSRKIEKSG-PDCKLRSFHLQSSAAGAKTEE--PINGMNWTN-TQGTEER
TEYLKKVRSILNIVNEGQI

PF12796 // ENSGT00390000001485_0_Domain_0 (440, 516)

SLLPHLAADNLDKIHDENGSNLLHIAASKGHAECLQHLTSL
MGEDCLNERNTEQLTPAGLAIKNGQL--ECVRWMV

ENSGT00390000001485_0_Linker_0_3 (516, 529)

S-ETEAIAELSCS

PF12796 // ENSGT00390000001485_0_Domain_3 (529, 602)

KDFPSLIHYAGC
YGQEK---ILLWLLQFMQEQGISLDEVDREGNSAVHVA-SQHGYLGCIQTLVEYGANVTM
Q

ENSGT00390000001485_0_Linker_3_5 (602, 627)

NHAGEKPSQSAERHGHTLCSRYLVV

PF16700 // ENSGT00390000001485_0_Domain_5 (627, 671)

VETCMSLASQVVKLTKQLKEQTVERVTLQSQLQQ
LLEAQKSEGKSLPSSPSSPSSPASTKSQWKALDTDEESTGKSKVGAQEGIQVLGSLSV--
SSRARTKGKD-EDSDKILR----QL------LGKEISENVC----------TQE--KLSL
EFQDAQA-SSRNSKKIPLEKRELKLARLRQLMQRSLSESDTDSNNSEDPKNTPVKRADRP
RPQPIVESVENADSAESLHLMIKKHS-LASGRRFP-FGMKASKS-LDGHSPSP-TSENSE
PDLDSHGPGLGMTPPTQPSAEATQSSPDSTTAQKVATSPKSALKSPSSKRRTSQNSKLRV
TFEEPVVQMEQTG-LELNG--EKDKDRGRAPQRT-----SESGEQMKRPFGTFRSIMESL
SGNQNNNNNYQPASQLKT-CTLPLTSLGRKT-ADAKGNPVSPASKGKNKAAM-YSSCIHL
PSNALVEEHLRDYARHNDIKRNATKTYHMKHTAEPEPRELFL

------------------------------------------------------------
---------QYSVTSLKTIPELC-------------------------------------
----------RRCDSQNEDRS-VSSSSWNCGVSTLITNTQKPTGIADVYSKFRPVKRVSP
LKHQPETLENNENDDQKSQK-VEYQKGDEPEPGPQPEEHSAGDGEGSL-PGKGTEP-GAL
LGELEHYDLDMDEILDVPYIKSSQQLASFTKVTSEKRILGLCTTINGLS-GKACSTGSAE
NSPCNLTPFCVLSPVKSPHLRKAS-SVVRDKHKLSTEELESSPPLVKCGS-TYEPENQSK
DFLHKTFSDPHSRKVEKAM-PDCQHRAFHLQASAAEPKPEE--QISGLNWTC-SQGPEER
SEYLKKVKSILNIVKEGQISLLPHLAADNLDKIHDE

PF00023 // ENSGT00390000001485_0_Domain_0 (457, 490)

SGNNLLHIAASQGHAECLQHLTSL
MGEDCLNERNTEKLTPAGLAIKNGQL--ECVRWMVS-ETEAIAELSCSK

PF00023 // ENSGT00390000001485_0_Domain_3 (530, 569)

DFPSLIHYAGC
YGQEK---ILLWLLQFMQEQGISLDEVD

ENSGT00390000001485_0_Linker_3_4 (569, 570)

Q

PF00023 // ENSGT00390000001485_0_Domain_4 (570, 603)

DGNSAVHIA-SQHGYLGCIQTLVEYGANVTM
QNHAGEKPSQSAERHGHTLCSRYLVVVETCMSLASQVVKLTKQLKEQTVERVTLQNQLQQ
LLEAQRSEGKSLPSSPSSPSSPTSRKSQWKPPDAEDESIAKSKPGVQEGIRVLGSLSA--
SSRARAKAKD-EDSDKILR----QL------LGKEISENVC----------TQE--KLSL
EFQDAQA-SSRNSKKIPPEKRELKLARLRQLMQRSLSESDTDSNHSEEPKTTPVKKAERP
RPQPIVESVESMDSAESLHLMIKKHT-LASGRRFP-FSIKASKS-LDGHSPSP-TSESSE
PDLESQYPGSGNTPPNQPPGDSTQPSPDSTAAQKVATSPKSALKSPSSKRRTSQNLKLRV
TFEEPVVQMEQTN-LELNG--EKDRDRGRTPQRTSTS--SESGDQLKRPFGTFRSIMETL
SGNQNNNNNYQAANQLKI-STPPLTSLGKKT-TDTKGNPMSLASKGKNKTET-YGSCISL
SSNMLIEEHLLNYARHNDINRKTKKSYSIKHIAKPEAEELFL

MEAPEYLDLD---EIDFSDDTS--------------------------------------
----------YSVTSLKTIPELC-------------------------------------
----------RRCDSQSEDRS-VSSSSWNCGVSTLITNTQKPTGIADVYSKFRPVKRVSP
LKHQPETLENNESDDQKNQK-TEYQKGSESDPGPQPEELSPGDREGIP-QSKSTEP-STL
LGELEHYDLDMDEILDVPYIKSNQQLASFTKVTSEKRILGLCTTINGLS-SKACSTGTPE
NSPSNMTPFCVLSPVKSPHLRKAS-SVVRDQQKLSTEEAESSPPLVKCGS-AYEPENQSK
DFLNKTFSDPHSRKVEKAM-PDCQLRAFHLQSSATETKLEE--QIGGMNWTS-SQGPEER
SEYLKKVKSILNIVKEGQISLLPHLAADNLDKIHDENGNNLLHIAASQGHAECLQHLTSL
MGEDCLSERNAEKLTPAGLAIKNGQL--ECVRWMVS-ETEAIAELSCSKDFPSLIHYAGC
FGQEK---ILLWLLQFMQEQGISLDEVDQ

PF00023 // ENSGT00390000001485_0_Domain_4 (570, 602)

DGNSAVHVA-SQHGYLGCIQTLVEYGANVTM
QNHVGEKPSQSAERHGHTLCSRYLVVVETCMSLASQVVKLTKQLKEQTMERVTLQNQLQQ
LLEAQKSEGKSLLSSPSSPSSPASRKSQWKSPDADDESLAKSKPGVQEGIQVLGSVSA--
SSRARAKAKD-EDSDKILR----QL------LGKDISENVC----------AQE--KLSL
EFQDAQA-SSRNSKKIPLEKRELKLARLRQLMQRSLSESDTDSNNSEDPKSTPVRKAERP
RPQPIVESVESMDSAESLHLMIKKHT-LASGRRFP-FGIKASKS-LDGHSPSP-TSESSE
PDLESHCPGSGTTPPNQPSGDSTQPSPDSTAAQKVATSPKSALKSPSSKRRTSQNLKLRV
TFEEPVVQMEQTS-LELNG--EKDRDKGRTFQRTSTS--SESGDQLKRPFGTFRSIMETL
SGNQNNNNNYQAANQLKT-STLPLTSLGRKT-ADAKGNPTSSASKGKNKAEM-YSSCINL
SSNPLIEEHLRNSARHNAINRKVKKSYSIKHIAEPEPKELFL

MEAPEYLDLD---EIDFSDDVSI-NRNQGNRIPRFGRGSL-WF-DLVMEDGGL--GYDWV
LGT-GC-PEEYSITSLKTIPELC-------------------------------------
----------RRCDPQSEDRP-VSSSSWNCXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLCTTLNGLS-GKAYPSGNAE
NPLCNQTPFCVLSPVKSPHLRKAS-SLLPDKHRLSTEELQSSPPLVQGSS-TYEPESQSK
DFLHSPFSEPHNRNVEKAK-PDCQHRAFHLQALAAESKPEE--QIGGLSWTC-PQGPEER
SEYAKKAKSILNIVKEGQISLLXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXX
XXXEK---ILLWLLQFMQEQGISLDEVDQ

PF00023 // ENSGT00390000001485_0_Domain_4 (570, 603)

DGNSAVHIA-SQHGYLGCIQTLVEYGANVTM
QNHAGEKPSQSAERHGHTLCSRYLVVVETCMSLASQXXXXXXXXXXQTVERVTLHNQLQQ
LLEAQRSEGKSLPSSPSSPSSPASRTSQWKPPDADDETIARSLPGVQEGIQILGSLSA--
SSRARTKAKD-EDSDKILR----QL------LGKEISENVC----------TQE--KLSL
KFQDAQA-CSRNAKKTPPEKRELKLARLRQLMQRSLSESDTDSNHSEDPKTTPVRKVDRP
RPQPLVESV---DGAESLHLMIKKHT-LASGRRFL-FSIKTSKS-LDGHSPSP-TSESSE
PDLETQYPGSGNTDPNQSLGDPTQPSSDSTAAQKAAPSPKSALKSPSSKRRTSQNLKLRV
TFEEPVVQMEQPN-LELHG--EKDKDRGRTPQRTSTN--SESGDRLKRPFGTFRSIMETL
SGNQNNNNNYQALSQLKL-STPPLTSLGKKT-ADAKGGSLSLSSKGKNKAGT-DSSGISL
SSSTLIGEQLRNSAGHNDINRKAKKSCSAKPIAEPEAEGFL-

MEAPEYLDLD---EIDFSDDIS--------------------------------------
----------YSVTSLKTIPELC-------------------------------------
----------RRCDSQSEDRS-VSSSGWNCSVSALITNTQKPTGIADVYSKFRPVKRVSP
LKHQPETLENNESDDQKNQK-VEYQKGGDSDPGPQPEELSPGDGDSGP-QSKSTEP-STL
LGELEHYDLDMDEILDVPYIKSSQQLASYTKVTPEKRILGLCTTINGLS-GKACSPGSAE
SSPANTTPFCVLSPVKSPQLRKTS-SVARDQQKLSAEESENSTALVKCGS-AYEPENQNK
DFLNKTFNDAPGRKREKAV-PDCQLRAFHLQSAATEPKLEE--PIGSGNWTS-SQGPEER
SEHLKKAKSILNIVKEGQISLLPHLAADNLDKIHDENGNNLLHVAASQGHAECLQHLTSL
MGEDCLSERNAEKLTPAGLAIKNGQL--ECVRWMVS-ETEAIAELSCSKDFPSLIHYAGC
FGQEK---ILLWLLQFMQEQGISLDEVDQ

PF00023 // ENSGT00390000001485_0_Domain_4 (570, 602)

DGNSAVHVA-SQHGFLGCIQTLVEYGANVTM
QNHAGEKPSQSAERHGHTLCSRYLVVVETCMSLASQVVKLTKQLKEQTMERVTLQNQLQQ
LLEAQKSE--SLLSSPSSPSSPASRRSQWKSPDADDESVAKSKPGVQEGIQVLGSLSA--
SSRARVKAKD-EDSDKILR----QL------LGKDISESVC----------TQE--KLSL
EFQDSQA-SSRNSKKIPLEKRELKLARLRQLMQRSLSESDTDSNTSEDPKSTPVRKADRP
RPQPIVGGMESVDSAESLHLMIKKHT-LTSGRRFP-FGIKASKS-LDGHSPSP-TSESSE
PDLESQCPGSGTTPPSQPSGDPTQPSPDSTVAQKMAMSPKSALKSPSSKRRTSQNLKLRV
TFEEPVVQMEQSS-LELNG--EKERDKGRTLQRASMS--SESGDQLKRPFGTFRSIMETL
SGNQNNNNNYQAANQLKT-STLPLTSLGRKT-TDAKGNPVNSASKGKNKAEM-YGSCITL
SSNTLTEEPQHNRARHNDINRKMKKSYSIKHNAEPESKELFL

MEAPEYLDLD---EIDFSDDIS--------------------------------------
----------YSVTSLKTIPELC-------------------------------------
----------RRCDSQNEDRS-VSSSSWNCGISTLITNTQKPTGIADVYSKFRPVKRVSP
LKHQPETLENNESDEQKDRK-VEDQKGDDSDQGSQTEELGPEDGGGLS-PGKGSEP-SCT
LGELEHYDLDMDEILDVPYIKSSQQLASFSRVTSEKRILGLCTTINGLS-GKACSTGSTE
NSPSNLTPFCVLPPVKSPHLRKAS-AVLRDPHKLPAEEPESSPPPVKCGS-AYEPESQNR
DFLNRAFSDPHNRKIEKTV-PDCQLRAVHVHSSAPEPNLEE--QVNGTNWTS-SQGPEER
SEYLKRAKSILNIVKEGQ

PF12796 // ENSGT00390000001485_0_Domain_0 (439, 516)

ISLLPHLAADNLDKIHDENGNNLLHIAAARGHAECLQHLTSL
MGEDCLSERNTEKLTPAGLAIKNGQL--ECVRWMV

ENSGT00390000001485_0_Linker_0_3 (516, 529)

S-ETEAIAELSCS

PF12796 // ENSGT00390000001485_0_Domain_3 (529, 602)

KDFPSLIHYAGC
YGQEK---ILLWLLQFMQEQGISLDEVDQDGNSAVHVA-SQHGYLGCIQTLVEYGANVTM
Q

ENSGT00390000001485_0_Linker_3_5 (602, 627)

NHVGDKPSQSAERHGHTLCSRYLVV

PF16700 // ENSGT00390000001485_0_Domain_5 (627, 671)

VETCMSLASQVVKLTKQLKEQTLERVTLQNQLQQ
LLEAQKSEGQSLPSSPSSPSSPASRKSQWRVPDVGDESTAKGKPGTQEGIQVLGSLSV--
SNRVRAKAKD-EDSDKILR----QL------LGKEISENVC----------TQE--KLTL
EFQDAHT-CSGNARKIPLEKRELKLARLRQLMQRPLSESDTDSNNSEDPKSTPVRRADRP
RPQPIVERVESVDSTESLHLIIKKHS-LASGRRFP-FSTKASKS-LDGHSPSP-TSESSE
PDLESQYPGSGTVPPSQPSGDPAQCSPDSTATPKVATSPKSALKSPSSKRRTSQNSKLRV
TFEEPVVQMEQTG-LELNG--EKDKDKGRTLPRNSAS--SEPGEQMKRPFGTFRSIMETL
SGNQNSNNNYQAAGQLKT-STLPLTSLGRKT-TDTKGNPSGSAGKGKNKAEM-YSSCTSL
SSNTLVEEHLHSHARHNDINRKMKKSYSTKHIAEPESKELFL

MEAPEYLDLD---EIDFSDDISVKHRNQGNRFQKLGLEGMR----------QGRLTVVAT
LGAGHCPENEYSVTSLKTIPELC-------------------------------------
----------RRCDSQNEDRP-VSNSSWNCGVSTLITNTQKPTGIADVYSKFRPVKRVSP
LKHQPEALENNESDDQKNQK-VEYQKGGESDPSPQPEELSPGDGAGGP-PGKSSEP-STS
LGELEHYDLDMDEILDVPYIKSSQQLASFTKVTSEKRILGLCTTINGLS-GKACSTGSAE
NLPSNMAPFCVLSPVKSPHLKKAS-TVIRDQHKLSTEEPESSPPLAKCSS-AYEPENQSK
DFLNKTFSDPHGRKVEKTM-PDCQLRAFNLQSSAAETKPEE--QVSGLNWTS-SQGPEER
SEYLKKVKSILNIVKEGQI

PF12796 // ENSGT00390000001485_0_Domain_0 (440, 516)

SLLPHLAADNLDKIHDENGNNLLHIAASQGHAECLQHLTSL
MGEDCLNERNTEKLTPAGLAIKNGQL--ECVRWMV

ENSGT00390000001485_0_Linker_0_3 (516, 532)

S-ETEAIAELSCSKDF

PF12796 // ENSGT00390000001485_0_Domain_3 (532, 602)

PSLIHYAGC
YGQEK---ILLWLLQFMQEQGISLDEVDQDGNSAVHVA-SQHGFLGCIQTLVEYGANVTM
Q

ENSGT00390000001485_0_Linker_3_5 (602, 627)

NHAGEKPSQSAERQGHTLCSRYLVV

PF16700 // ENSGT00390000001485_0_Domain_5 (627, 671)

VETCMSLASQVVKLTKQLKEQTVERVTLQNQLQQ
LLEAQKSEGKSLPSSPSSPSSPASRKSQWKSPEADDESVAKSKSGVQEGIQVLGSLSA--
TSRARTKAKD-EDSDKILR----QL------LGKEISENVC----------TQE--KLSL
EFQDAQS-SSRNSKKIPLEKRELKLARLRQLMQRSLSESDTDSNNSEDPKNTPVRKVDRP
RPQPIVESVESMDSAESLHLMIKKHTLASGGRRFP-FSIKASKP-LDGHSPSP-TSESSE
PDLESQYPGPGNSPPSQPSGDTTQPSPDSTAAQKVATSPKSALKSPSSKRRTSQNSKLRV
TFEEPVVQMEQPS-PELNG--EKDKDKGRTLQRTSTS--SESGDQLKRPFGTFRSIMETL
SGNQNNNNNYQGANQLKT-STLPLTSLGRKT-TDAKGNPASSTSKGKNKAGM-YSSCINL
SSNTLAEEHLRNYARHDDINRKMKKSYSIKHIAEPESKELFL

MEAPEYLDLD---EIDFSDDIS--------------------------------------
----------YSVTSLKTIPELC-------------------------------------
----------RRCDSQNEDRS-VSSSSWNCGISTLITNTQKPTGIADVYSKFRPVKRVSP
LKHQPETLENNESDDQKNHK-VEYQKEGDPDQGPQTEELGPEDGVGGL-PGKSSEP-SSA
LGELEHYDLDMDEILDVPYIKSSQQLASFSKVTSEKRILGLCTTINGLS-GKACSTGSTE
NSSSNMTPFCVLSPVKSPHLRKAS-AVLRDPHKLSTGESESSPPPIKCGS-AYEPESQNK
DFLNKAFNDPRNRKIEKTM-PDCQLRAFHVQSSATEPKLDE--QVNGMNWTS-SQGLEER
NEYLKKVKSILNIVKEGQISLLPHLAADNLDKIHDENGNNLLHITASRGHVECLQHLTSL
MGEDCLNERNAEKLTPAGLAIKNGQL--ECVRWMVS-ETEAIAELSCS

PF12796 // ENSGT00390000001485_0_Domain_3 (529, 602)

KDFPSLIHYAGC
YGQEK---ILLWLLQFMQEQGISLDEVDQDGNSAVHVA-SQHGYLGCIQTLVEYGANVTM
Q

ENSGT00390000001485_0_Linker_3_5 (602, 627)

NHVGDKPSQSAERHGHTLCSRYLVV

PF16700 // ENSGT00390000001485_0_Domain_5 (627, 671)

VETCMSLASQVVKLTKQLKEQTVERVTLQNQLQQ
LLEAQKSEGKSLPSSPSSPSSPASRKSQWRVPDIGDESTAKSKLGIQEGIQVLGSLSA--
SSGVRAKTKE-EDSDKILR----QL------LGKEISENVC----------TQE--KLTL
EFQDAQA-CSRHSKKIPLEKRELKLARLRQLMQRSLSESDTDSNNSEDPKNTPVRRADRP
RPQPIVESVESMDSTESLHLMIKKHS-LASGRRFP-FSTKASKS-LDGHSPSP-TSESSE
PDLESQYPGSGNIPPSQPSGDPTQSSPDSTAAQKVATSPKSALKSPSSKRRTSQNSKLRV
TFEEPVVQMEQTG-LELNG--EKDKDKGRTLPRNSTS--SESGEQLKRPFGTFRSIMETL
SGNQNNNNNYQTAIQLKT-STLPLTSLGRKM-TDAKGNPVNSAGKGKTKAEM-YSSCINL
SSNMLIEEHLHNCARHNDINRKMK-KYSIRHIAEPESKELFL

MEAPEYLDLD---EIDFSDDIS--------------------------------------
----------YSVTSLKTIPELC-------------------------------------
----------RRCDSQNEDRS-VSSSSWNCGVSTLITNAQKPTGIAEVYSKFRPVKRVSP
LKHQPETLENNESDDQKNHK-VEYPKVGESDQGPQPEELGPEDGVGGL-PSKSSES-STA
LGELEHYDLDMDEILDVPYIKSSQQLASFTKVTSEKRILGLCTTINGLS-GKASSTGSTE
NSPSSMTPFCVLSPVKSPHLRKAS-TVLRDQHKLSTEESESSPPLVTCGS-AYEPESQNK
DFLNKAFSDLHSRKIEKTM-PDCQLRGFHLQSAATESKLEE--PVKVMSWTS-SQGPEER
NEYLKKVKSILNIVKEGQISLLPHLAADNLDKIHDENGNNLLHIAASQGHAECLQHLTSL
MGEDCLNERNTEKLTPAGLAIK--------------------------------------
-------------------------------------------------TLVEYGANVTM
QNHAGEKPSQSAERQGHTLCSRYLVV

PF16700 // ENSGT00390000001485_0_Domain_5 (627, 671)

VETCMSLASQVVKLTKQLKEQTMERVTLQNQLQQ
LLEAQKSEGKSLPSSPSSPSSPASRKSQWKSSDAEDESTAKSKPGVQEGIQVLGNLSA--
SSRARAKAKD-EDSDKILR----QL------LGKEISENVC----------TQE--KLSL
EFQDAQT-TSRNLKKIPLEKRELKLARLRQLMQRSLSESDTDSNNSEDPKNTPVRKADRP
RPQPIVESVESIDSTESLHLMIKKHS-LASGRRFP-FSTKASKS-LEGHSPSP-TSESSE
PDLEPQCPVSGNTPPSQPSGEPTQCSPDSTAAQKVAMSPKSALKSPSSKRRTSQNLKLRV
TFEEPVVQMEQTN-LELNG--EKDKDKGRTLQRTPTS--SESGEQLKRPFGTFRSIMETL
SGNQNNNNNYQAATQLKT-STLPLTSLGRKM-TDAKGNPASSASKGKNKAEM-YSSCIHL
SSNRLIEEHLRNYARHNDINRTMKKSYSIKHIDEPESKELFL

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------TLVEYGANVTM
QNHAGEKPSQSAERHGHTLCSRYLVV

PF16700 // ENSGT00390000001485_0_Domain_5 (627, 671)

VETCMSLASQVVKLTKQLKEQTVEHVTLQNQLQQ
LLEAQKSEGKSLPSSPSSPSSPASRKSQWKILDADDEATGKSKPGAQEGIQVLGSLSA--
SSRARTKGKD-EDSDKILR----QL------LGKEISENVC----------NQE--KLSL
EFQDAQA-SSRNSKKIPLEKRELKLARLRQLMQRSLSESDTDSNNSEDPKNTPVRRADRP
RPQPIVESVENMDSTESLHLMIKKHS-LASGRRFP-FSTKASKS-LDGHSPSP-TSESSE
PDLDSHCPGLGMTSPTQPSADPSQSSPDSSTAQKVATSPKSALKSPSSKRRTSQNSKLRV
TFEEPVVQVEQTS-LELNG--EKDKDRVRAPQRT-----SESGEQMKRPFGTFRSIMETL
SGNQNNNNNYQPANQLKT-CTLPLTSLGRKT-ADTKGNPVSPGSKGKNKAA---------
------------------------------------------

MEAPEYLDLD---EIDFSDEIS--------------------------------------
----------YSVTSLKTIPELC-------------------------------------
----------RRCDSQNEDRS-VSSSTWNCGVSTLITNAQKPTGIADVYSKFRPVKRVSP
LKHHPETLENNESDDQKNEK-VEYQKGGAFDQPPPTEQLCPGDGE-AL-KSKSIEP-SVL
LGELEHYDLDMDEILDVPYIKSSQQLASFTKAATEKRIVGICSTVNGLS-GKSNSTGNAE
NLTTSMTPFCVLSPVKSSHLRKAP-SLVLDQHKHSSEDPELSPALLPCNS-VHEPEPPSK
GFLNKAFADPNMLKVENILPNSGQLRTLHLQSSATEPKLDE--QKSHVSWN--PGVPEER
SEDVKKIKSILNIVKEGQISLLPHLAADNLDQIHDERGNNLLHVAASQGHAECLQHLTSL
MGEDCLNERNEDKLTPAGLAIKNGQL--ECVRWMVS-ETEAIAELSCSKDFPSLIHYAGC
YGQEK---ILLWLLQFMQEQGISLDEVDQ

PF00023 // ENSGT00390000001485_0_Domain_4 (570, 602)

DGNSAVHVT-SQHGYLGCIQTLVEYGANVTM
QNHAGEKPSQSAERHGHTMCSRYLVVVETCMSLASQVVKLTKQLKEQTMERVTLQNQLQQ
LLEAQRSEGKALLSSPSSPSSPASGKSLWNSADADELCPAKSKPSAQDGIQVLGSLAA--
SSRTKFKAKD-DDSDKILR----QL------LGKEISENVC----------TQE--KLSL
EFQDAQA-SSRSVKKMPPEKRELKLARLRQLMQRSLSESDTDSNNSEDLKNTPVRRTDKP
RPQPIVESVE---SAESLHLMIKKHT-LAAGRRFP-FSIRASKS-ADGHSPSP-TSESSD
LDLESQCPAPGSTPQGQPPGDLPPAAPDGAAATKAATSPKSALKSPSSKRRTAPNLKLRV
TFEEPVVQVEQTE-LELGA--EKDKERVRAPPRLPPS--SEPSDQLKRPFGTFRSIMETL
SGNQNNNNNCQAAQQPRTSSTLPFTSLGRRA-ADAKGSTVGSASKGKSKAA---------
------------------------------------------

MEAPEYLDLD---EIDFSDDI---------------------------------------
---------SYSVTSLKTIPELC-------------------------------------
----------RRCDSQNEDRS-VSGSGWNCGVSTLITNTQKPTGIADVYSKFRPVKRVSP
LKHQPETLDSNESDDQKNQK-GDLQKGGDSDAGPQPEELGPEEGVGGL-PGKGSEP-SPA
LGELEHYDLDMDEILDVPYIKSNQQLASFSKVASDKRILGLCTTINGLATGKACCAGGAE
NPPPTTTPFCVLSPVKSPHLRKAS-TAIRDQHKLGPEESESAPALVSCVS-AYEPETQSR
DFPNKAFAEPHGGKAEKAL-PDCQLRAFRLPCSAAEATLEE--QVNGVSWPT-CQGPEEK
TEHQKKVKSILNIVREGQISLLPHLAADNLDKIHDENGNNLLHIAASQGHAECLQHLTSL
MGEDGLNERNAGKLTPAGLAIKNGQL--ECVRWMVS-ETEAIAELSCSRDFPSLIHYAGC
YGQEK---ILLWLLQFMQEQGISLDEVDQ

PF00023 // ENSGT00390000001485_0_Domain_4 (570, 602)

DGNSAVHVA-SQHGFLGCIQTLVEYGANVTM
QNHAGEKPSQSAERHGHTLCSRYLVVVETCMSLASQVVKLTKQLKEQTVERVTLQTQLQQ
LLEAQKTEGKSLPSSPSSPSSPASKTAQWKAPDTDEESAARTKPGIQEGIQVLGSLSA--
ASRARAKAKD-EDSDKILR----QL------LGKEISENVC----------TQE--KLSL
EFQDAQT--SRNPKKIPAEKRELKLARLRQLMQRSLSESDTDPTNPEDPKSTPVRKSDRP
RPQPIVESVEGAEGTESLHLMIKKHS-LASGRRFP-FGIKASRS-LDGHSPSP-TSESCE
ADLESQYPGPGSAPPSQAPGDPTQPSPDSPAAQKVATSPKSALKSPSSKRRTSQNLKLRV
TFEEPVVQMEQTS-PDPSG--ERDKDRGRTLPRTSPG--SESGDQLKRPFGTFRSIMETL
SGNQNNSNNYQVASQLKT-STLPLTSLGRKT-TDAKGSPVSSAGKGKNKAGL-FGSCVSL
SSNTLTEEHLPGCARPNDISRKMKKSYSIKHIAEPEPEELFL

MEAPEYLDLD---EIDFSDDIS--------------------------------------
----------YSVTSLKTIPELC-------------------------------------
----------RRCDSQNEDRA-VSSSSWNCGISTLITNTQKPTGIADVYSKFRPVKRVSP
LKHQPETLENNESDDQKNHK-VEYQKGGESDQGPQTEELSPEDGGGSL-PGKGTEP-NAE
LGELEHYDLDMDEILDVPYIKSSQQLASFTKVTSEKRILGLCATLNGLS-VKACSPGSTE
NCPSSTTPFCVLSPVKSPHLRKAS-AVLREPHKLSTEESESSPSPVKIGS-AYEPENQNK
DFLNKAFGDSHNRKIEKTA-PNCHLRAFHSQSSATEPPMEE--QVSGTVWIS-SQGPEER
NEYLKKVKSILNIVKEGQISLLPHLAADNLDKIHDENGNNLLHIAASQGHAECLQHLTSL
MGEDCLSERNTEKLTPAGL

PF12796 // ENSGT00390000001485_0_Domain_3 (500, 602)

AIKNGQL--ECVRWMVS-ETEAIAELSCSKDFPSLIHYAGC
YGQEK---ILLWLLQFMQEQGISLDEVDQDGNSAVHVA-SQQGYLGCIQTLVEYGANVTM
Q

ENSGT00390000001485_0_Linker_3_5 (602, 627)

NNVGEKPSQSAERHGHSLCSRYLVV

PF16700 // ENSGT00390000001485_0_Domain_5 (627, 671)

VETCMSLASQVVKLTKQLKEQTMERVMLQSQLQQ
LLEAQKSEGMSLPSSPSSPSSPASRKSQWRITDAGDESVAKSKPGAQEGIQVLGSFAA--
TSRVRAKAKD-EDSDKILR----QL------LGKEISENVC----------TQE--KLTL
EFQDAQA-CSRNSRKIPLEKRELKLARLRQLMQRSLSESDTDSNNSEDPKHTPVRKADKP
RPQPIVESVESMDSTESLHLMIKKHS-LASGRRFP-FSTKASKS-LDGHSPSP-TSEGSE
PDVESQYSGLGNMALSQPSGDPTQSNPDSTTTQKVATSPKSALKSPSSKRRTSQNLKLRV
TFEEPVVQMEQSG-LELSG--DK--DKGRTLPRSSAS--SESGEQLKRPFGTFRSIMETL
SGNQNNNNNYGAASQPKT-STLPLTSLGRKT-AEAKGNPTSSASKGKNKAEM-YSSCSSL
SSNPLPEEHLHNYARPNDTDRKMKKSYSIKHIAEPQSKELFL

MEAPEYLDLD---EIDFSDDIS--------------------------------------
----------YSVTSLKTIPELC-------------------------------------
----------RRCDSQNEDKS-VSSSSWNCGVSTLLGNAQKPTGIADVCNKFRPVKRVSP
LKHHPESSENNESDDQKNQK-GEYQKGSDSQCAPPNDDQSPGEGESL--KSKSTEP-AVL
LGELEHYDLDMDEILDVPYIKSSQQPVPFTKVAPEKKLLSVCSTVNGPS-VKTCPAGSTE
SLPAGSMQFCVLSPVKGTQLRKTQ-PIVLDQHKHSTEELELSQPLVKCSS-AHESEARGK
GFFSKTLADPLAHKAEKIM-PNCHQRTFHLQTALAESKQLEE---LSMNWSS-AGGPEER
SEEVKKIKSILNIVKEGQISLLPHLAADNLDKIHDECDNNLLHVAASKGHAECLQHLTSL
MGEDCLNERNILQLTPAGLAIKNG--QLECVRWMVS-ETEAIAELSCSKDHPSLIHYAGC
YGQEK---ILLWLLQFMQEQGISLDEVDQ

PF00023 // ENSGT00390000001485_0_Domain_4 (570, 602)

DGNTAVHIA-AQHGYLGCIQTLVEYGANVTM
QNHVGEKPSQSAERHGHTLCSRYLVVVETCMSLASQVVKLTKQLKEQTVERVTLQNQLQQ
LLEAQRSEGKSLPTSPSLSSSPTSGKSQWKLSEADELSPPKSKLNTQDGIQILGSLGMST
STHARAKIKD-EDSDKILR----QL------LGKEISENVC----------MQE--KLTL
EFQDAHA-SSKNVKKILPEKRELKLARLRQLMQRSLSESDTDSANSEDHKNTPVKRTDKP
RPQPIVESVE---STESLNMMLKKHT-SIAGWRFP-FGIRVSKS-VDGYSPSP-TSESSD
VDNESPYQ-SGTVPQNQFCGDNSPSSTDSATAQKVATSPKSALKSPSSKRRTSQNLKLRV
TFEEPVVQVELTE-SELNE--EKDKDRSKGLVQAPASSADHAGDQLKRPFGAFRSIMETL
SGNQNNNNNCPTANLIKTSSTLPFTSLGRKT-TESKGNPAV-VSKGRNKPV---------
------------------------------------------

MEAPEYLDLD---EIDFSDDIS--------------------------------------
----------YSVTSLKTIPELC-------------------------------------
----------RRCDAQSEDRS-VSSSSWNCSVSALITNTQKPTGIADVYSKFRPVKRVSP
LKHQPETLDNNESDDQKNQK-VECQKGSDSEPGPPPEELSPGDGDSGP-QSKSTEP-STL
LGELEHYDLDMDEILDVPYIKSSQQLAPFTKVTSDKRILGLCTTINGLS-GKACSPGSAE
SSPSTLTPFCVLSPVKSPHLRKAS-SIIRDQQKLSAEESESSPPLVKCGS-AYEPENQSK
DFLNKTFSDPHSRKREKAM-PDCQLRDFHPQSSATEPKVEE--QIGGVSWTS-SQGPEER
SEYLKKGKSILNIVKEGQISLLPHLAADNLDKIHDETGNNLLHVAASQGHAECLQHLTSL
MGEDCLSERNAERLTPAGL

PF12796 // ENSGT00390000001485_0_Domain_3 (500, 600)

AIKNGQL--ECVRWMVS-ETEAIAELSCSKDFPSLIHYAGC
FGQEK---ILLWLLQFMQEQGISLDEVDQDGNSAVHVA-SQHGYLGCIQTLVEYGANVT

ENSGT00390000001485_0_Linker_3_5 (600, 627)

M
HNHAGEKPSQSAERHGHTLCSRYLVV

PF16700 // ENSGT00390000001485_0_Domain_5 (627, 671)

VETCMSLASQVVKLTKQLKEQTMERVTLQNQLQQ
LLEAQKSEDKSLLSSPSSPSSPASRRSQWKSPDADDESVAKSKPGVQEGIQVLGSLSA--
SSRARAKAKD-EDSDKILR----QL------LGKDISESVC----------TQE--KLSL
EFQDAQA-SSRNSKKIPADKRELKLARLRQLMQRSLSESDTDSNTSEDPKSTPVRKADRP
RPQPIVGSVESVDSAESLHLMIKKHT-LASGRRFP-FGIKASKS-LDGHSPSP-TSESSE
PDLESQCPASGTTPPSQPSGDPTQPSPDSTATQKVAMSPKSALKSPSSKRRTSQNLKLRV
TFEEPVVQMEQAS-LEPTG--EKDRDKGRTPQRTSTG--SESGDQLKRPFGTFRSIMETL
SGNQNNNNNYQAANQLKT-STLPLTSLGRKT-TDAKRSPVSSASKGKNKAEM-YGSCVTL
SSNTLTEEPLRNRARHNDINRKMKKSYSIKHIAEPESNELFL

MEAPEYLDLD---EIDFSDDISD-NRSQGNRLQKLGLEDTDREDALGFGSHRAKLTVVAA
LGACHCPENEYSVTSLKTIPELC-------------------------------------
----------RRCDTQNEDRS-VSSSSWNCGISTLITNTQKPTGIADVYSKFRPVKRVSP
LKHQPETLENNESDDQKNQKVVEYQKGGESDLGPQPEELSPGDGVGGP-PGKSSEP-STS
LGELEHYDLDMDEILDVPYIKSSQQLASFTKVTSEKRILGLCTTINGLS-GKACSTGSSE
SSSSNMAPFCVLSPVKSPRLRKAS-SVIRDQHKLATEETEISPPLVKCGS-AYEPENQSK
DFLNKTFSDPHGRKVEKTT-PDCQLRAFHLQSSAAESKSEE--QVSGLNWTS-SQGPEER
SEYLKKVKSILNIVKEGQI

PF12796 // ENSGT00390000001485_0_Domain_0 (440, 516)

SLLPHLAADNLDKIHDENGNNLLHIAASQGHAECLQHLTSL
MGEDCLNERNTEKLTPAGLAIKNGQL--ECVRWMV

ENSGT00390000001485_0_Linker_0_3 (516, 532)

S-ETEAIAELSCSKDF

PF12796 // ENSGT00390000001485_0_Domain_3 (532, 602)

PSLIHYAGC
YGQEK---ILLWLLQFMQEQGISLDEVDQDGNSAVHVA-SQHGYLGCIQTLVEYGANVTM
Q

ENSGT00390000001485_0_Linker_3_5 (602, 627)

NHAGEKPSQSAERQGHTLCSRYLVV

PF16700 // ENSGT00390000001485_0_Domain_5 (627, 671)

VETCMSLASQVVKLTKQLKEQTVERVTLQNQLQQ
FLEAQKSEGKSLPSSPSSPSSPACRKSQWKSPDADDDSVAKSKPGVQEGIQVLGSLSA--
SSRARPKAKD-EDSDKILR----QL------LGKEISENVC----------TQE--KLSL
EFQDAQA-SSRNSKKIPLEKRELKLARLRQLMQRSLSESDTDSNNSEDPKNTPVRKADRP
RPQPIVESVESMDSAESLHLMIKKHTLASGGRRFP-FSIKTSKS-LDGHSPSP-TSESSE
PDLESQYPGSGSTPPNQPSGDPPQPNPDSTAAQKVATSPKSALKSPSSKRRTSQNLKLRV
TFEEPVVQMEQPS-LELNG--EKDKDKGRTLQRTSTS--NESGDQLKRPFGAFRSIMETL
SGNQNNNNNYQAANQLKT-STLPLTSLGRKT-TDAKGNPASSTNKGKNKAEM-YSSCINL
SSNTLIEEHLRNYARHNDINRKMKKSYSIKHIAEPESKELFL

MEAPEYLDLD---EIDFSDDISD-NRNQGNR-IRLGLGSRDREGTWVFGSVKGKITVVAT
LGAGHCPENAXXXXXXXXXXXXX-------------------------------------
----------XXXXXXXXXXX-XSSSSWNCSVSTLITNTQKPTGIADVYSKFRPVKRVSP
LKHQPETLENNESDDQKNQK-AEYQKGGDSDPGPQPEELSPRDGESSP-PSKSTEP-SPL
LGELEHYDLDMDEILDVPYIKSSQQLASFAKVTSEKRILGLCTSISGLS-SKACSTGNAE
NSLSNMTPFCVLSPVKSPHLRKTS-SVVRDQQKLSTEESESSPPLVKCGS-AYEPENQSK
DFPNKIFSEPHGRKVDKAM-PDCQLRAFHLQSSAPDPKLEE--QVSGVNWTS-SQGPEER
SEYLKKVKSILNIVKEGQISLLPHLAADNLDKIHDE

PF00023 // ENSGT00390000001485_0_Domain_0 (457, 490)

SGNNLLHVAAAQGHAECLQHLTSL
MGEDCLNERNVEKLTPAGLAIKNGQL--ECVRWMVS-ETEAIAELSCSK

PF00023 // ENSGT00390000001485_0_Domain_3 (530, 569)

DFPSLIHYAGC
FGQEK---ILLWLLQFMQEQGISLDEVD

ENSGT00390000001485_0_Linker_3_4 (569, 570)

Q

PF00023 // ENSGT00390000001485_0_Domain_4 (570, 603)

EGNSAVHVA-SQHGYLGCIQTLVEYGANVTM
QNHAGEKPSQSAERHGHTLCSRYLMVVETCMSLASQVVKLTKQ-EEQTMQRVTLQNQLQQ
LLEAQKSEGKSLLSSPSSPSSPASRKSQWKSPDADDEPIGKSKPGIQEGIQVLGSLSV--
SSRARAKAKD-EDSDKILR----QL------LGKDISENVC----------TQE--KLSL
EFQDAQA-SSRNSKKTPLEKRELKLARLKQLMQRPLSESDTDSNNSEDPKGTPVRKVDRP
RPQPVVESMESMDSAESLHLMIKKHS-LASGRRFP-FSIKASKS-LEGHSPSP-TSESSE
PDLESQSPGSGTVPPNQPSGELPQPSPDSTAAQKVATSPKSALKSPSSKRRTSQNLKLRV
TFEEPVVQMEQTS-LELNG--EKDRDKGRALQRTSAS--SEPGDQLKRPFGTFRSIMETL
SGNQNNNNNYQASNQLKT-STLPLTSLGRKT-ADGKGNPGSSASKGKNKAEM-YDSCINL
SSNTLIEEHLCDYARHNDINRKMKKSYSIKHVAELESKEFFL

MEAPEYLDLD---EIDFSDDIS--------------------------------------
----------YSVTSLKTIPELC-------------------------------------
----------RRCDSQNEDRS-VSNSSWNCGVSTLITNPQKPTGIADVYSKFRPVKRVSP
LKHQPETLENNENDDQKSHA-VEYQKGIESDQGPQHEELGPADGVGGL-PGKGSEP-SPE
LGELEHYDLDMDEILDVPYIKSSQQLASLSKVTTEKRILGLCTTINGLS-GKVCSPGSTE
NAPSNMTPFCVLSPVKSPHVRRAA-AALREQHKLAPDDSESFSPLLQCGS-AYEPESPGK
DFLKKAFSEPHSPKLEKTL-SGCQLRAFHLQPPATEPRPEE--QVKGLAWTT-SHGPEER
SEYLKKARSMLNIVKEGQISLLPHLAADNLDKIHDENGNNLLHVAASQGHAACLQHLTSL
MGEDCLSERNAEKLTPAGLAIKNGQL--ECVRWMVS-ETEAIAELSCS

PF12796 // ENSGT00390000001485_0_Domain_3 (529, 602)

KDFPSLIHYAGC
YGQEK---ILLWLLQFMQEQGISLDEVDQDGNSAVHVA-SQHGYLGCIQTLVEYGANVTT
Q

ENSGT00390000001485_0_Linker_3_5 (602, 627)

NHAGEKPSQSAERRGHTLCSRYLVV

PF16700 // ENSGT00390000001485_0_Domain_5 (627, 671)

VETCMSLASQVVKLTRQLKEQTVERVTLQNQLQQ
LLEAQKSEGKSLPSSPSSPSSPASRKSQWKIPDADDETTAKSKPVVQEGIQILRSLSA--
PGRARAKAKD-EDSDKILR----QL------LGKEISENVC----------TQE--KLSL
EFQDAQA-CSRNLKKVPLEKRELKLARLRQLMQRSLSESDTDSTTSEDSKNTPVRRADRP
RPQPIVESAESGDGAESLHLMIKKHS-LASGRRFPPFSAKASKS-LGEHSPSP-TSESSE
PDLDAQGPGSGGTPPSQPAADP---NPDGTAAQKVATSPKSALKSPSSKRRTSQNSKLRV
TFEEPVVQMEQTS-LELGG--DKDKDRNKSLPRSSAA--SEPVEPLKKPFGTFRSIMETL
SGNQNNSNNCQAAHQLKT-STLPLTSLGRKM-PDAKGNPMSSASKGKNKADT-YSSCTSL
SSNPLVEELLRNPARHNDISRRTKKSDSTKHVAEPESKELFL

MEAPEYLDLD---EIDFSDDISD-NRSQGNRP-QLGLEDTDREDALGFGSHRAKLTVVAA
LGACHCPENEYSVTSLKTIPELC-------------------------------------
----------RRCDTQNEDRS-VSSSSWNCGISTLITNTQKPTGIADVYSKFRPVKRVSP
LKHQPETLENNESDDQKNQKVVEYQKGGECDLGPQPEELSPGEGVGGP-PGKSSEP-STS
LGELEHYDLDMDEILDVPYIKSSQQLASFTKVTSEKRILGLCTTINGLS-GKACSTGSSE
SSSSNMAPFCVLSPVKSPHLRKAS-AVIRDQHKLATEETEISPPLVKCGS-AYEPENQSK
DFLNKTFSDPHGRKVEKTT-PDCQLRAFHLQSSAAESKPEE--QVSGLNWTS-SQGPEER
SEYLKKVKSILNIVKEGQI

PF12796 // ENSGT00390000001485_0_Domain_0 (440, 516)

SLLPHLAADNLDKIHDENGNNLLHIAASQGHAECLQHLTSL
MGEDCLNERNTEKLTPAGLAIKNGQL--ECVRWMV

ENSGT00390000001485_0_Linker_0_3 (516, 532)

S-ETEAIAELSCSKDF

PF12796 // ENSGT00390000001485_0_Domain_3 (532, 602)

PSLIHYAGC
YGQEK---ILLWLLQFMQEQGISLDEVDQDGNSAVHVA-SQHGYLGCIQTLVEYGANVTM
Q

ENSGT00390000001485_0_Linker_3_5 (602, 627)

NHAGEKPSQSAERQGHTLCSRYLVV

PF16700 // ENSGT00390000001485_0_Domain_5 (627, 671)

VETCMSLASQVVKLTKQLKEQTVERVTLQNQLQQ
FLEAQKSEGKSLPSSPSSPSSPASRKSHWKSPDADDDSVAKSKPGVQEGIQVLGSLSA--
SSRARPKAKD-EDSDKILR----QL------LGKEISENVC----------TQE--KLSL
EFQDAQA-SSRNSKKIPLEKRELKLARLRQLMQRSLSESDTDSNNSEDPKNTPVRKADRP
RPQPIVESVESMDSAESLHLMIKKHTLASGGRRFP-FSIKTSKS-LDGHSPSP-TSESSE
PDLESQCPGSGSTPPNQPSGDPPQPNPDSTAAQKVATSPKSALKSPSSKRRTSQNLKLRV
TFEEPVVQMEQPS-LELNG--EKDKDKGGTLQRTSTS--NESGDQLKRPFGAFRSIMETL
SGNQNNNNNYQAANQLKT-STSPLTSLGRKT-TDAKGNPASSTNKGKNKAEM-YSSCVNL
SSNTLIEEHLRNYARHNDINRKMKKSYSIKHIAEPESKELFL

MEAPEYLDLD---EIDFSDDIS--------------------------------------
----------YSVTSLKTIPELC-------------------------------------
----------RRCDSQNEDRS-VSSSGWNCSVTTLITNAQKPTGIADVYSKFRPVKRVSP
LKHQPETLDNNESDDQKNQK-AEYQKGGDTDADPQPEELSPGGDREGG-PQTKTAE-TAL
LGELEHYDLDMDEILDVPYIKSSQQLAPFPKMAPEKRVLGLCTTINGLS-GKVCATGNAE
NSPSTTTPFCVLSPVKSPHPRKAS-SVLRDQPKLSPEDTESSPPLAKCGSAAYEPESQSK
DFLSKAFSDAHGRNVEKPL-PDCQLRAFHLQTSAAEPKLEE--QVGGLSWTS-SQGPEER
SEYLQKVKSILNIVKEGQISLLPHLAADNLDKIHDE

PF00023 // ENSGT00390000001485_0_Domain_0 (457, 491)

SGNNLLHIAASQGHAECLQHLTSL
MGEDCLNERN

ENSGT00390000001485_0_Linker_0_2 (491, 492)

A

PF00023 // ENSGT00390000001485_0_Domain_2 (492, 530)

EKLTPAGLAIKNGQL--ECVRWMVS-ETEAIAELSCSKDFPSLIHYAGG
FGQEK---ILLWLLQFMQEQGISLDEVDQ

PF00023 // ENSGT00390000001485_0_Domain_4 (570, 603)

DGNSAVHVA-SQHGYLGCIQTLVEYGANVTM
QNHTGDKPSQSAERHGHTLCSRYLVVVETCMSLASQVVKLTKQLKEQTVERVTLQHQLQQ
LLEAQRSEGKSLLSSPSLPCSPASRKSQWKSPDTDDESVAKSKPGVQEGMPVLASLSA--
SSRARAKAKD-EDSDRILR----QL------LGKDISENVC----------TQE--KLSL
EFQDTQA-SSRNSKKIPPEKRELKLARLRQLMQRSLSESDTDSNTSEDPKSTPVRKAERP
RPQPIVESAEAIDSAESLHLMIKKHT-LASGRRFP-FGIKASKS-LDGHSPSP-TSESSE
PDLESHGPGSGTTPPNQPSGDPTLPSPDSTAAQKVATSPKSALKSPSSKRRTSQNLKLRV
TFEEPVVQMEQTG-LELNG--EKDRDKGRTLQRTSTS--SESGDQLKRPFGTFRSIMETL
SGNQNNNNNYQAVNQLKT-CTLPLTSLGRKT-TDTKGNPVSSASKGKNKAV---------
------------------------------------------

MEAPEYLDLD---EIDFSDEI---------------------------------------
---------SYSVTSLKTIPELC-------------------------------------
----------RRCDSQNEDRSAVSSSSWNCGVSTLITNTQKPTGIADVYSKFRPVKRVSP
LKHQPETLENNESDDQKNQK-AEYQKGEESDPGPPPEELGPRDGAGGP-PGKSSEP-STS
LGELEHYDLDMDEILDVPYIKSSQQLPSFTKVASEKRILGLCTTINGLS-GKACSLGSSE
NSPSTMAPFCVLSPVKSPHLRKPL-TVIRDPHKFSAEEPQSSPPLAKCGS-AYEPET---
----LPFSDSHSHKVEKAV-PDCQLRAFHLQSAPAEPKPEE--QVNGLTWTS-SQGLEER
SEYVKKVKSILNIVKEGQISLLPHLAADNLDKIHDENGNNLLHIAASQGHAECLQHLTSL
MGEDCLNERNSEKLTPAGLAIKNGQL--ECVRWLVS-ETEAIAELSCSKDFPSLIHYAGC
YGQEK---ILLWLLQFMQEQGISLDEVDQ

PF00023 // ENSGT00390000001485_0_Domain_4 (570, 602)

DGNSAVHVA-SQHGYLGCIQTLVEYGANVTM
QNHAGEKPSQSAERQGHTLCSRYLVVVETCMSLASQVVKLTKQLKEQTVERVTLQNQLQQ
LLEAQKSEGKSLPSSPSSPSSPASRKSQWKSPDTEDESIAKNKPGVQEGIQVLGSLAA--
ASRARAKVKD-EDSDKILR----QL------LGKEISENVC----------TQE--KLSL
EFQDVQA-SSRNLKKIPLEKRELKLARLRQLMQRSLSESDTDSNNSEDPRNTPVRKADRP
RPQPIVESVESMDNAESLHLMIKKHT-LTTGRRFP-FGIKASKS-LDGHSPSP-TSESSE
PDLEPQYGGTGSAPPNQASGDPTQTNPDSTTAQKIATSPKSALKSPSSKRRTSQNLKLRV
TFEEPVVQMEQTS-LELSG--EKDKERGRTLHRASAS--GEAGDQLKRPFGTFRSIMETL
SGNQNNNNNYQAASQLKT-TTLPLTSLGRKT-ADVKGNPASSANKGKNKAEI-HSSCINL
SSNLLAEERLHNSLRHNDINRKMKKSYSMKHIAEPESKELFL

MEAPEYLDLD---EIDFSDDIS--------------------------------------
----------YSVTSLKTIPELC-------------------------------------
----------RRCDSQNEDRS-VSSSSWNCGVSTLLGNAQKPTGIADVCNKFRPVKRVSP
LKHQPESSENNESDDQKNQK-GEYQKGNDSQSAPPNDDQSPGEGESL--KSKCTEP-AVL
LGELEHYDLDMDEILDVPYIKSSQQPVPFTKVAAEKKLLSVCSTMNGLS-VKSCPAGSTE
SSPTGGTQFCVLSPVKGAQLRKTQ-PIVLDQHKHSAEELELSQPSVKCSS-AHDSEAQGK
GFLSRTVADPHAHKAEKTM-PNCHRRTFHLQTAVAESKQLEE---LGMSWSS-TGGPEDR
NEEVKKIKSILNIVKEGQISLLPHLAADNLDKIHDECDNNLLHVAASKGHAECLQHLTSL
MGEDCLNERNIEQLTPAGLAIKNG--QLECVRWMVS-ETEAIAELSCSKDHPSLIHYAGC
YGQEK---ILLWLLQFMQEQGISLDEVDQ

PF00023 // ENSGT00390000001485_0_Domain_4 (570, 602)

DGNTAVHIA-AQHGYLGCIQTLVEYGANVTM
QNHVGEKPSQSAERHGHTMCSRYLVVVETCMSLASQVVKLTKQLKEQTVERVTLQNQLQQ
LLEAQRSEGKSLPTSPSLPSSPTSGKPQWKPSEADELSPPKSKLNTQDGIQILGSLGTST
SSRARSKIKD-EDSDKILR----QL------LGKEISENVC----------MQE--KLTL
EFQDAHA-SSKNVKKILPEKRELKLARLRQLMQRSLSESDTDSANSEDHKNTPVKRTDKP
RPQPIVESVE---STESLNMMLKKHT-STAGRRFP-FGIRVSKS-VDGHSPSP-TSESSD
PDNEAPYQ-SGTVPQSQFCGDNSPSSTDSATAQKVATSPKSALKSPSSKRRTSQNLKLRV
TFEEPVVQVELAE-SELNE--EKDKERSKGLVRAPASSGEHAGDQLKRPFGAFRSIMETL
SGNQNNNNNCQTANLIKASSTLPFTSLGRKT-TESKGNPAV-VSKGRNKPDP-YFSYTSL
SSSTLNE-ELCNCAWHDDISWKIQKSDSQKSTEEPELQEFFL

MEAPEYLDLD---EIDFSDDISD-NRSQGNRLQKLGLEDTGREDALGFGSHRAKLTVVAA
LGACHCPENEYSVTSLKTIPELC-------------------------------------
----------RRCDTQNDDRS-VSSSSWNCGISTLITNTQKPTGIADVYSKFRPVKRVSP
LKHQPETLENNESDDQKNQKVAEYQKGGESDPGPQPEDLGPGDGVGGP-PGKSSEP-STS
LGELEHYDLDMDEILDVPYIKSSQQLASFTKVTSEKKILGLCTTINGLS-GKVCSTGSSE
NSPSNMAPFCVLSPMKSPHLRKAS-AVIRDQHKLSTEEPEISPPLVKCGS-AYEPENQSK
DFLNKTFSDSHGRKVEKTT-PDCQLRAFHLQSSAAESKQEE--QVSSLNWTS-SQSPEER
SEYLKKVKSILNIVKEGQI

PF12796 // ENSGT00390000001485_0_Domain_0 (440, 516)

SLLPHLAADNLDKIHDENGNNLLHIAASQGHAECLQHLTSL
MGEDCLNERNTEKLTPAGLAIKNGQL--ECVRWMV

ENSGT00390000001485_0_Linker_0_3 (516, 532)

S-ETEAIAELSCSKDF

PF12796 // ENSGT00390000001485_0_Domain_3 (532, 602)

PSLIHYAGC
YGQEK---ILLWLLQFMQEQGISLDEVDQDGNSAVHVA-SQHGYLGCIQTLVEYGANVTM
Q

ENSGT00390000001485_0_Linker_3_5 (602, 627)

NHAGEKPSQSAERQGHTLCSRYLVV

PF16700 // ENSGT00390000001485_0_Domain_5 (627, 671)

VETCMSLASQVVKLTKQLKEQTVERVTLQNQLQQ
FLEAQKSEGKSLPSSPSSPSSPASRKSQWKSPDADDDSVAKSKPGVQEGIQVLGSLSA--
SSRARPKAKD-EDSDKILR----QL------LGKEISENVC----------TQE--KLSL
EFQDAQA-SSRNSKKIPLEKRELKLARLRQLMQRSLSESDTDSNNSEDPKNTPVRKADRP
RPQPIVESVESMDSTESLHLMIKKHTLSSGGRRFP-FGIKASKS-LDGHSPSP-TSESSE
PDLESQYPGSGSTPPNQPSGDPPQHSPDSTAAQKVATSPKSALKSPSSKRRTSQNLKLRV
TFEEPVVQMEQPS-LELNG--EKDKDKGRTLQRTSTS--NESGDQLKRPFGAFRSIMETL
SGNQNNNNNYQAANQLKT-STLPLTSLGRKT-TDAKGNPASSASKGKNKAEM-YSSCINL
SSNTLIEEHLRNYTRHNDINRKMKKSYSIKHIAEPESKELFL

MEAPEYLDLD---EIDFSDDISD-NRSQGNRLQKLGLEDTGREDALGFGSHRAKLTVVAA
LGACY-PENEYSVTSLKTIPELC-------------------------------------
----------RRCDTQNEDRS-VSSSSWNCGISTLITNTQKPTGIADVYSKFRPVKRVSP
LKHQPETLENNESDDQKNQKVVEYQKGGESDPGTQPEDLTPGDGVGGP-PGKSSEP-STS
LGELEHYDLDMDEILDVPYIKSSQQLASFTKVTSEKRILGLCTTINGLS-GKVCSTGSSE
NSPSNMAPFCVLSPMKSPHLRKAS-AVIHDQHKLSTEEPEISPPLVKCGS-AYEPENQSK
DFLNKTFSDSHGRKVEKTT-PDCQLRAFHLQSSTAESKQEE--QVSSLNWTS-SQSPEER
SEYLKKVKSILNIVKEGQI

PF12796 // ENSGT00390000001485_0_Domain_0 (440, 516)

SLLPHLAADNLDKIHDENGNNLLHIAASQGHAECLQHLTSL
MGEDCLNERNTEKLTPAGLAIKNGQL--ECVRWMV

ENSGT00390000001485_0_Linker_0_3 (516, 532)

S-ETEAIAELSCSKDF

PF12796 // ENSGT00390000001485_0_Domain_3 (532, 602)

PSLIHYAGC
YGQEK---ILLWLLQFMQEQGISLDEVDQDGNSAVHVA-SQHGYLGCIQTLVEYGANVTM
Q

ENSGT00390000001485_0_Linker_3_5 (602, 627)

NHAGEKPSQSAERQGHTLCSRYLVV

PF16700 // ENSGT00390000001485_0_Domain_5 (627, 671)

VETCMSLASQVVKLTKQLKEQTVERVTLQNQLQQ
FLEAQKSEGKSLPSSPSSPSSPASRKSQWKSPDADDDSVAKSKPGVQEGIQVLGSLSA--
SSRARPKAKD-EDSDKILR----QL------LGKEISENVC----------TQE--KLSL
EFQDAQA-SSRNSKKIPLEKRELKLARLRQLMQRSLSESDTDSNNSEDPKNTPVRKADRP
RPQPIVESVESMDSTESLHLMIKKHTLASGGRRFP-FSIKASKS-LDGHSPSP-TSESSE
PDLESQYPGSGSTPPNQPSGDPPQPSPDSTAAQKVATSPKSALKSPSSKRRTSQNLKLRV
TFEEPVVQMEQPS-LELNG--EKDKDKGRTLQRTSTS--NESGDQLKRPFGAFRSIMETL
SGNQNNNNNYQAANQLKT-STLPLTSLGRKT-TDAKGNPASSANKGKNKAEM-YSSCINL
SSNTLIEEHLRNYARHNDINRKMKKSYSIRHIAEPESKELFL

MHKPGNADNSSPILIACISLSP--------------------------------------
----------YSVTSLKTIPELC-------------------------------------
----------RRCDSQNEDRAAVSSSGWNCGISALITNTQKPTGIADVYSKFRPVKRVSP
LKHQPETLENNESDEQKNRK-VEHQKGGESDQGPQAEEFGPEHGGGSV-PGKSSEP-LAA
LGELEHYDLDMDEILDVPYIKSSQQLASFTKVTSEKRILGLCTTLNGLS-VKACSPGSTE
NPPSSLTPFCVLSPVKSPHLRKAS-AVLRDSHKLSTEESESSPPPVKCGS-AYEPENHNK
DFLSKAFGDPHNRKVEKTA-PDCHLKTFHTQSSTTESTLGE--QVNGMVWTS-SQGPEEK
NEYLKKVKSILNIVKEGQ

PF12796 // ENSGT00390000001485_0_Domain_0 (439, 516)

ISLLPHLAADNLDKIHDENGNNLLHIAASQGHAECLQHLTSL
MGEDCLNERNAEKLTPAGLAIKNGQL--ECVRWMV

ENSGT00390000001485_0_Linker_0_3 (516, 529)

S-ETEAIAELSCS

PF12796 // ENSGT00390000001485_0_Domain_3 (529, 602)

KDFPSLIHYAGC
YGQEK---ILLWLLQFMQEQGISLDEVDQDGNSAVHVA-SQQGYLGCIQTLVEYGANVTM
Q

ENSGT00390000001485_0_Linker_3_5 (602, 627)

NHVGEKPSQSAERHGHTLCSRYLVV

PF16700 // ENSGT00390000001485_0_Domain_5 (627, 671)

VETCMSLASQVVKLTKQLKEQTMERVMLQNQLQQ
LLEAQKSEGKSLPSSPSSPSSPASRKSHWRVPDASDESVAKSKPGVQEGIQVLGSLSA--
SSRVRAKAKD-EDSDKILR----QL------LGKEISENVC----------TQE--KLTL
EFQDAQA-CSRNSKKIPLEKRELKLARLRQLMQRSLSESDTDSNNSEDPKHTPVRKADRP
RPQPIVESLENMDNTESLHLMIKKHS-LASGRRFP-FSTKASKS-LDGHSPSP-TSESSE
PDLESQCPGSGNTPPSQPSGDPMQFSPDSTAAQKVATSPKSALKSPSSKRRTSQNLKLRV
TFEEPVVQMEQSS-PELNG--DK--DKGRTLPRSSTS--SEPGEPLKRPFGTFRSIMETL
SGNQNNNNNYPAASQPKT-STLPLTALGKKL-VDTKGNPTSSASKGKNKAEM-YSSCISL
TSNTLVEEHLHNYARHNDINRKMKKPYSIKHIAEPQSKELFL

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---EK---ILLWLLQFMQEQGISLDEVDQEGNSAVHVA-SQHGYLGCIQTLVEYGANVTM
QNHAGEKPSQSAERHGHTLCSRYLVV

PF16700 // ENSGT00390000001485_0_Domain_5 (627, 671)

VETCMSLASQVVKLTKQLKEQTVERVTLQSQLQQ
LLEAQKSEGKSLPSSPSSPSSPASRKSQWKILDADDEATGKSKPGVQEGIQVLGSLSA--
SSRARTKGKD-EDSDKILR----QL------LGKEISENVC----------TQE--KLSL
EFQDAQA-SSRNSKKIPLEKRELKLARLRQLMQRSLSESDTDSNNSEDPKNTPVRKADRP
RPQPIVESVENMDSAESLHLMIKKHS-LATGRRFP-FSTKASKS-LDGHSPSP-TSESSE
PDLDSHCPSLGKTSPTQPPADPSQSSPDSSTAQKVATSPKSALKSPSSKRRTSQNSKLRV
TFEEPVVQVEQTS-LELNG--EKDKDRGRAPQRT-----SEPGEQMKRPFGTFRSIMETL
SGNQNNNNNYQPANQLKT-CTLPLTSLGRKT-PDTKGTPAGSASKGKNKAA---------
------------------------------------------

MEAPEYLDLD---EIDFTDDIS--------------------------------------
----------YSVTSLKTIPALC-------------------------------------
----------RRCDSQNEDRS-VSSSGWNCGVSTLITNPQKPTGIADVYSKFRPVKRVSP
LKHQPETLENNENEDQKNNT-VEYQKRGEPDQGPQSEALNPEDGVGGL-PGKGSEP-SQA
LGELEHYDLDMDEILDVPYIKSSQQLAPLTKVTSEKRILGLCTTINGLS-AKTCPIASTE
NSTPNMTPFCVLSPVKSPHLRKAP-TALQSQHMFSTEESESSPPLGKCGP-AYESENHSK
DFLNKVFSDPHSRKVEKSG-PDCKLRSFHLQSSAAGAKTEE--PINGMNWTN-AQGTEER
TEYLKKVRSILNIVNEGQI

PF12796 // ENSGT00390000001485_0_Domain_0 (440, 516)

SLLPHLAADNLDKIHDENGNNLLHVAASKGHAECLQHLTSL
MGEDCLNERNTEQLTPAGLAIKNGQL--ECVRWMV

ENSGT00390000001485_0_Linker_0_3 (516, 529)

S-ETEAIAELSCS

PF12796 // ENSGT00390000001485_0_Domain_3 (529, 602)

KDFPSLIHYAGC
YGQEK---ILLWLLQFMQEQGISLDEVDREGNSAVHVA-SQHGYLGCIQTLVEYGANVTM
Q

ENSGT00390000001485_0_Linker_3_5 (602, 627)

NHAGEKPSQSAERHGHTLCSRYLVV

PF16700 // ENSGT00390000001485_0_Domain_5 (627, 671)

VETCMSLASQVVKLTKQLKEQTVERVTLQSQLQQ
LLEAQKSEGKSLPSSPSSPSSPASRKSQWKILDTDEESTGKSKVGAQEGIQVLGSLPV--
SSRARTKGKD-EDSDKILR----QL------LGKEISENVC----------TQE--KLSL
EFQDAQV-SSRNSKKIPLEKRELKLARLRQLMQRSLSESDTDSNNSEDPKNTPVKRADRP
RPQPIVESVENVDSAESLHLMIKKHS-LASGRRFP-FGMKASKS-LDGHSPSP-TSESSE
PDLDSHGPGLGMTPPTQPSTEATQSSPDSTTAQKVATSPKSALKSPSSKRRTSQNSKLRV
TFEEPVVQMEQTG-LEING--EKDKDRGRAPQRT-----SESGEQMKRPFGTFRSIMESL
SGNQNNNNNYQPASQLKT-CTLPLTSLGRKT-ADAKGNPVSPASKGKNKAAM-YGSCIHL
PSNALVEEHLRDYARHNDIKRNATKTYHVKHTAEPEPKELFL

MEAPEYLDLD---EIDFSDDIS--------------------------------------
----------YSVTSLKTIPELC-------------------------------------
----------RRCDTQNEDRS-VSSSSWNCGISTLITNTQKPTGIADVYSKFRPVKRVSP
LKHQPETLENNESDDQKNQKVVEYQKGGESDLGPQPQELSPGDGVGGP-PGKSSEP-STS
LGELEHYDLDMDEILDVPYIKSSQQLASFTKVTSEKRILGLCTTINGLS-GKACSTGSSE
SSSSNMAPFCVLSPVKSPHLRKAS-AVIHDQHKLSTEETEISPPLVKCGS-AYEPENQSK
DFLNKTFSDPHGRKVEKTT-PDCQLRAFHLQSSAAESKAEE--QVSGLNWTS-SQGPEER
SEYLKKVKSILNIVKEGQISLL--------------------------------------
----------------------NGQL--ECVRWMVRCETKAIAELSCSKDFPSLIHYAGC
YGQEK---ILLWLLQFMQEQGISLDEVDQ

PF00023 // ENSGT00390000001485_0_Domain_4 (570, 602)

DGNSAVHVA-SQHGYLGCIQTLVEYGANVTM
QNHAGEKPSQSAERQGHTLCSRYLVVVETCMSLASQVVKLTKQLKEQTVERVTLQNQLQQ
FLEAQKSEGKSLPSSPSSPSSPASRKSQWKSPDADDDSVAKSKPGVQEGIQVLGSLSA--
SSRARPKAKD-EDSDKILR----QL------LGKEISENVC----------TQE--KLSL
EFQDAQA-SSRNSKKIPLEKRELKLARLRQLMQRSLSESDTDSNNSEDPKNTPVRKADRP
RPQPIVESVESMDSAESLHLMIKKHTLASGGRRFP-FSIKASKS-LDGHSPSP-TSESSE
PDLESQYPGSGSIPPNQPSGDPPQPSPDSTTAQKVATSPKSALKSPSSKRRTSQNLKLRV
TFEEPVVQMEQPS-LELNG--EKDKDKGRTLQRTSTS--NESGDQLKRPFGAFRSIMETL
SGNQNNNNNYQAANQLKT-STLPLTSLGRKT-TDAKGNPASSASKGKNKAA---------
------------------------------------------

MEAPEYLDLD---EIDFSDDISD-NRSQGNKLQKLGLEDTDREDALGFGSHRAKLTVVAA
LGACHCPENEYSVTSLKTIPELC-------------------------------------
----------RRCDTQNEDRS-VSSSSWNCGISTLITNTQKPTGIADVYSKFRPVKRVSP
LKHQPETLENNESDDQKNQKVVEYQKGGESDLGPQPEELSPGDGVGGP-PGKSSEP-STS
LGELEHYDLDMDEILDVPYIKSSQQLASFTKVTSEKRILGLCTTINGLS-GKACSTGSSE
SSSSNMAPFCVLSPVKSPRLRKAS-AVIRDQHKLATEETEISPPLVKCGS-AYEPENQSK
DFLNKTFSDPYGRKVEKTT-PDCQLRAFHLQSSAAESKPEE--QVSGLNWTS-SQGPEER
SEYLKKVKSILNIVKEGQI

PF12796 // ENSGT00390000001485_0_Domain_0 (440, 516)

SLLPHLAADNLDKIHDENGNNLLHIAASQGHAECLQHLTSL
MGEDCLNERNTEKLTPAGLAIKNGQL--ECVRWMV

ENSGT00390000001485_0_Linker_0_3 (516, 532)

S-ETEAIAELSCSKDF

PF12796 // ENSGT00390000001485_0_Domain_3 (532, 602)

PSLIHYAGC
YGQEK---ILLWLLQFMQEQGISLDEVDQDGNSAVHVA-SQHGYLGCIQTLVEYGANVTM
Q

ENSGT00390000001485_0_Linker_3_5 (602, 627)

NHAGEKPSQSAERQGHTLCSRYLVV

PF16700 // ENSGT00390000001485_0_Domain_5 (627, 671)

VETCMSLASQVVKLTKQLKEQTVERVTLQNQLQQ
FLEAQKSEGKSLPSLPSSPSSPASRKSHWKSPDADDDSVAKSKPGVQEGIQVLGSLSA--
SSRARPKAKD-EDSDKILR----QL------LGKEISENVC----------TQE--KLSL
EFQDAQA-SSRNSKKIPLEKRELKLARLRQLMQRSLSESDTESNNSEDSKNTPVRKADRP
RPQPIVESVESMDSAESLQLMIKKHTLASGGRRFP-FSIKTSKS-LDGHSPSP-TSESSE
PDLESQYPGSGSSPPNQPSGDPPQPNPDSTAAQKVATSPKSALKSPSSKRRTSQNLKLRV
TFEEPVVQVEQPS-LELNG--EKDKDKGRTLQRTSTS--NESGDQLKRPFGAFRSIMETL
SGNQNNNNNYQAANQLKT-STLPLTSLGRKT-PDAKGNPASSTNKGKNKAEM-YSSCINL
SSNTLIEEHLRNYARHNDINRKMKKSYSIKHIAEPESKELFL

------------------------------------------------------------
------------------------------------------------------------
----------------------VSSSSWNCGGSTLIGNAQKPTGIADACNKFRPVKRVSP
LKHQPESSENNESDDQKNQK-GEYQKGSDAQPAPPNDDQNPGEGENL--KSKNIEP-TVL
LGELEHYDLDMDEILDVPYIKSNQQLVPT-------------------------------
-EPAGVTQFCVLSPVKGSQLRKTQ-PIVVDQHKHLTEELELSQPLAKCSS-VHESEAQGK
GFLCRTFVGPQAHKTEKTM-PNCHLRTFHLQTAVAESKQLEE---LNMSWSR-AGGPEER
NEEVKKSKSILNIVKEGQISLLPHLAADNLDKIHDE

PF00023 // ENSGT00390000001485_0_Domain_0 (457, 490)

CDNNLLHVAASKGHAECLQHLTSL
MGEDCLNERNMEQLTPAGLAIKRSM-ELNGVSWLKS-IFKGICDLNCFSSFTVLVHF--C
YSLEK---ILLWLLQFMQEQGISLDEVDQ

PF00023 // ENSGT00390000001485_0_Domain_4 (570, 603)

DGNTAVHIA-AQHGYLGCIQTLVEYGANVTM
QNHMGEKPSQSAERHGHTMCSRYLVVVETCMSLASQVVKLTKQLKEQTVERVTLQNQLQQ
LLEAQRSEGKSLPTSTSFSPE-LKSDLQWIALTKDQNSRNF-------TYYLFS-VH--A
SPRSRHNLKE-EERDSSSR----HIEISSVVHGNQVSTQLLSQDDTERNKVIQVQIGLSL
SLSSNSVSSTEGTHSVFPCFTELRRSSILQNLMH--------------------------
----CFEQVH---HDSEVHLSVFQTS-ASSYKVCP-FSHKDNSKWAEGEHHSNEFHVSSE
KGDNSPSS-PASGKPQWKPSEAAPSSTDSASAQKVATSPKSALKSPSSKRRTSQNLKLRV
TFEEPVVQVELAE-AELNE--EKDKERGKALSRAPPSTGEPLGDQLKRPFGTFRSIMETL
SGNQNNNNNCQMANLIKTSSTLPFSSLGRKT-ADSKGNPAA-LTKGRNKPGP-CFSHTSL
SSSTLNEEHLCNYA----------------------------

MEAPEYLDLD---EIDFSDDISD-NRSQGNRLQKLGLEDTDREDAMGFGSHRAKLTVVAA
LGACHCPENEYSVTSLKTIPELC-------------------------------------
----------RRCDTQNEDRS-VSSSSWNCGISTLITNTQKPTGIADVYSKFRPVKRVSP
LKHQPETLENNESDDQKNQKVVEYQKGGESDLGPQPQELGPGDGVGGP-AGKSSEP-STS
LGELEHYDLDMDEILDVPYIKSSQQLASFTKVTSEKRILGLCTTINGLS-GKACSTGSSE
SSSSNMAPFCVLSPVKSPHLRKAS-AVIHDQHKLSTEETEISPPLVKCGS-AYEPENQSK
DFLNKTFSDPHGQKVEKTT-PDCQLRAFHLQSSAAESKPEE--QVSGLNRT--SQGPEER
SEYLKKVKSILNIVKEGQI

PF12796 // ENSGT00390000001485_0_Domain_0 (440, 516)

SLLPHLAADNLDKIHDENGNNLLHIAASQGHAECLQHLTSL
MGEDCLNERNTEKLTPAGLAIKNGQL--ECVRWMV

ENSGT00390000001485_0_Linker_0_3 (516, 532)

S-ETEAIAELSCSKDF

PF12796 // ENSGT00390000001485_0_Domain_3 (532, 602)

PSLIHYAGC
YGQEK---ILLWLLQFMQEQGISLDEVDQDGNSAVHVA-SQHGYLGCIQTLVEYGANVTM
Q

ENSGT00390000001485_0_Linker_3_5 (602, 627)

NHAGEKPSQSAERQGHTLCSRYLVV

PF16700 // ENSGT00390000001485_0_Domain_5 (627, 671)

VETCMSLASQVVKLTKQLKEQTVERVTLQNQLQQ
FLEAQKSEGKSLPSSPSSPSSPASRKSQWKSPDADDDSVAKSKPGVQEGIQVLGSLSA--
SSRARPKAKD-EDSDKILR----QL------LGKEISENVC----------TQE--KLSL
EFQDAQA-SSRNYKKIPLEKRELKLARLRQLMQRSLSESDTDSNNSEDPKTTPVRKADRP
RPQPIVESVESMDSAESLHLMIKKHTLASGGRRFP-FSIKASKS-LDGHSPSP-TSESSE
PDLESQYPGSGSIPPNQPSGDPQQPSPDSTAAQKVATSPKSALKSPSSKRRTSQNLKLRV
TFEEPVVQMEQPS-LELNG--EKDKDKGRTLQRTSTS--NESGDQLKRPFGAFRSIMETL
SGNQNNNNNYQAANQLKT-STLPLTSLGRK--TDAKGNPASSASKGKNKAEM-YSSCINL
SSNMLIEEHLRNDTRHNDINRKMKKSYSIKHIAEPESKELFL

MEAPEYLDLD---EIDFSDDISD-NRSQGNRLQKLGLEDTDREDALGFGSHRAKLTVVAA
LGACHCPENEYSVTSLKTIPELC-------------------------------------
----------RRCDTQNEDRS-VSSSSWNCGISTLITNTQKPTGIADVYSKFRPVKRVSP
LKHQPETLENNESDDQKNQKVVEYQKGGESDLGPQPEELSPGDGVGGP-PGKSSEP-STS
LGELEHYDLDMDEILDVPYIKSSQQLASFTKVTSEKRILGLCTTINGLS-GKACSTGSSE
SSSSNMAPFCVLSPVKSPHLRKAS-AVIRDQHKLATEETEISPPLVKCGS-AYEPENQSK
DFLNKTFSDPHGRKVEKTT-PDCQLRAFHLQSSAAESKPEE--QVSGLNWTS-SQGPEER
SEYLKKVKSILNIVKEGQI

PF12796 // ENSGT00390000001485_0_Domain_0 (440, 516)

SLLPHLAADNLDKIHDENGNNLLHIAASQGHAECLQHLTSL
MGEDCLNERNTEKLTPAGLAIKNGQL--ECVRWMV

ENSGT00390000001485_0_Linker_0_3 (516, 532)

S-ETEAIAELSCSKDF

PF12796 // ENSGT00390000001485_0_Domain_3 (532, 602)

PSLIHYAGC
YGQEK---ILLWLLQFMQEQGISLDEVDQDGNSAVHVA-SQHGYLGCIQTLVEYGANVTM
Q

ENSGT00390000001485_0_Linker_3_5 (602, 627)

NHAGEKPSQSAERQGHTMCSRYLVV

PF16700 // ENSGT00390000001485_0_Domain_5 (627, 671)

VETCMSLASQVVKLTKQLKEQTVERVTLQNQLQQ
FLEAQKSEGKSLPSSPSSPSSPACRKSQWKSPDADDDSVAKSKPGVQEGIQVLGSLSA--
SSRARPKAKD-EDSDKILR----QL------LGKEISENVC----------TQE--KLSL
EFQDAQA-SSRNSKKIPLEKRELKLARLRQLMQRSLSESDTDSNNSEDPKNTPVRKADRP
RPQPIVESVQSMDSAESLHLMIKKHTLASGGRRFP-FSIKTSKS-LDGHSPSP-TSESSE
PDLESQYPGSGSTPPNQPSGDPPQPSPDSTAAQKVATSPKSALKSPSSKRRTSQNLKLRV
TFEEPVVQMEQPS-LELNG--EKDKDKGRTLQRTSTS--NESGDQLKRPFGAFRSIMETL
SGNQNNNNNYQAANQLKT-STLPLTSLGRKT-TDTKGNPASSTNKGKNKAEM-YSSCINL
SSNTLIEEHLHNYARHNDINRKMKKSYSIKHIAEPESKELFL

MEAPEYLDLD---EIDFSDDIS--------------------------------------
----------YSVTSLKTIPELC-------------------------------------
----------RRCDSQNEDRA-VSSSSWNCGISTLLTNTQKPTGIADVYSKFRPVKRVSP
LKHQPETLENNESDDQKNHK-GEYQKGGESDQGPQAEELSPEDGGGSV-PGKSSEP-SSA
LGELEHYDLDMDEILDVPYIKSSQQLASFTKAPSEKRILGLCTTLNGLS-GKACSPGSSE
NSPSTMTPFCVLSPVKSPPSRKAP-AVFRDPHKLPTEAAENSPPPGKCVL-AYAPENQNK
GFLNKAFSDPHDRKMEKTA-PDCHLRAFHSQSSASEPNLEE--QVSGTAWTS-SQGPEER
NEHLKKVKSILNIVKEGQISLLPHLAADNLDKIHDDSGNNLLHVAASQGHAECLQHLTSL
MGEDCLNERNVEKLTPAGL

PF12796 // ENSGT00390000001485_0_Domain_3 (500, 602)

AIKNGQL--ECVRWMVS-ETEAIAELSCSKDFPSLIHYAGC
YGQEK---ILLWLLQFMQEQGISLDEVDYEGNSAVHVA-SQHGYLGCIQTLVEYGANVTM
QNHAGEKPSQSAERHGHTLCSRYLVVVETCMSLASQVWVVLLITYN----------LWTI
FFTCKKYSAQHLPGK---HEVPSSISNSKKQKEYS-----K-------------------
---THALMSR-GNGEVVLLHIIFPW------YMKTLSYI-----------------IATQ
TGNNAQA-CSRNPKKIPLEKRELKLARLRQLMQRSLSESDTDSNNSEDPKNTPVRKADRP
RPQPIVESVENMDSTESLHLMIKKHS-LASGRRFP-FSTKASKS-LDGHSPSP-TSENSE
PDLESQCLGLGSIPQSQPSGDPTQSNPDSAAAQKVATSPKSALKSPSSKRRTSQNLKLRV
TFEEPVVQMEPSSVLELDGDKDKDRDKGRTLPRNSTS--SESGEQLKRPFGTFRSIMESL
SGNQNNNNNCPAASQLKT-STLPLTSLGRKT-ADNKGNPVSSASKGKSKAVS-ALWRISF
F---LLG-----------------------------------

MEAPEYLDLD---EIDFSDDISD-NRSQGNRLQKLGLEDTGRGDALGFGSCRAKLTVVAA
LGDCHCPENEYSVTSLKTIPELC-------------------------------------
----------RRCDTQNEDKS-VSSSSWNCGISTLITNTQKPTGIADVYSKFRPVKRVSP
LKHQPETLENNESDDQKNQKVVEYQKGGESDLGHQPEDLSPGDGLGGP-PGKNSEP-STP
LGELEHYDLDMDEILDVPYIKSSQQLASFTKVTSEKRILGLCTSINGLS-GKVCSTGSSE
NSPSNMAPFCVLSPLKSPHLRKAS-AVIRDQHKLSTEEPEISPPLVKCGS-AYE--NQSK
DFLNKTFSDSHGRKVEKTT-PDCQLRAFHLQSSAAESKQEE--QVSSMNWPS-SQSPEER
SEYLKKVKSILSIVKEGQI

PF12796 // ENSGT00390000001485_0_Domain_0 (440, 516)

SLLPHLAADNLDKIHDENGNNLLHIAASQGHAECLQHLTSL
MGEDCLNERNTEKLTPAGLAIKNGQL--ECVRWMV

ENSGT00390000001485_0_Linker_0_3 (516, 533)

S-ETEAIAELSCSKDFP

PF12796 // ENSGT00390000001485_0_Domain_3 (533, 602)

SLIHYAGC
YGQEK---ILLWLLQFMQEQGISLDEVDQDGNSAVHVA-SQHGYLGCIQTLVEYGANVTM
Q

ENSGT00390000001485_0_Linker_3_5 (602, 627)

NHAGEKPSQSAERQGHTLCSRYLVV

PF16700 // ENSGT00390000001485_0_Domain_5 (627, 671)

VETCMSLASQVVKLTKQLKEQTVERVTLQNQLQQ
FLEAQKSEGKSLPSSPSSPSSPASRKSQWKSPDADDDSVAKSKPGVQEGIQVLGSLSA--
SSRARPKAKD-EDSDKILR----QL------LGKEISENVC----------TQE--KLSL
EFQDAQA-SSRNSKKIPLEKRELKLARLRQLMQRSLSESDTDSNNSEDPKNTPVRKADRP
RPQPIVESVESMDSTESLHLMIKKHTLASGGRRFP-FGIKASKS-LDGHSPSP-TSESSE
PDLESQYPGSGSTPPNQPSGDPPQPSPDSTAAQKVATSPKSALKSPSSKRRTSQNLKLRV
TFEEPVVQMEQPS-LELNG--EKDKDKGRTLQRTSTS--NESGDQLKRPFGAFRSIMETL
SGNQNNNNNYQAANQLKT-STLPLTSLGRKT-ADAKGNPASSASKGKNKAEM-YSSCINL
SSNTLIEEHWRNYARHNDINRKMKKSCSIKHIAEPESKELFL